CL1_2028 6ee9b65ba7ebd28be1308e88f995b905 331 Gene3D G3DSA:3.30.70.2580 1 57 4.7E-5 T 30-10-2018 CL1_2028 6ee9b65ba7ebd28be1308e88f995b905 331 SUPERFAMILY SSF53335 72 329 2.09E-72 T 30-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CL1_2028 6ee9b65ba7ebd28be1308e88f995b905 331 Pfam PF02475 Met-10+ like-protein 82 277 7.4E-73 T 30-10-2018 IPR030382 SAM-dependent methyltransferase TRM5/TYW2-type Reactome: R-HSA-6782861 CL1_2028 6ee9b65ba7ebd28be1308e88f995b905 331 Gene3D G3DSA:3.40.50.150 143 331 6.4E-57 T 30-10-2018 CL1_2028 6ee9b65ba7ebd28be1308e88f995b905 331 Gene3D G3DSA:3.30.300.110 58 142 2.1E-29 T 30-10-2018 CL1_0794 76de3301482e795264dfd4deea7bc405 670 SMART SM00926 1 49 3.5E-9 T 30-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CL1_0794 76de3301482e795264dfd4deea7bc405 670 Pfam PF00384 Molybdopterin oxidoreductase 52 472 9.4E-91 T 30-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CL1_0794 76de3301482e795264dfd4deea7bc405 670 SUPERFAMILY SSF50692 524 658 2.68E-36 T 30-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily CL1_0794 76de3301482e795264dfd4deea7bc405 670 Gene3D G3DSA:3.40.228.10 129 326 2.5E-172 T 30-10-2018 CL1_0794 76de3301482e795264dfd4deea7bc405 670 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 5 47 7.3E-8 T 30-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CL1_0794 76de3301482e795264dfd4deea7bc405 670 Gene3D G3DSA:2.20.25.90 1 51 7.3E-9 T 30-10-2018 CL1_0794 76de3301482e795264dfd4deea7bc405 670 Gene3D G3DSA:3.40.50.740 58 516 2.5E-172 T 30-10-2018 CL1_0794 76de3301482e795264dfd4deea7bc405 670 Pfam PF01568 Molydopterin dinucleotide binding domain 552 650 9.8E-23 T 30-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 CL1_0794 76de3301482e795264dfd4deea7bc405 670 TIGRFAM TIGR01591 Fdh-alpha: formate dehydrogenase, alpha subunit 4 655 1.4E-266 T 30-10-2018 IPR006478 Formate dehydrogenase, alpha subunit GO:0008863|GO:0015942|GO:0055114 KEGG: 00630+1.17.1.9|KEGG: 00680+1.17.1.9|MetaCyc: PWY-1881|MetaCyc: PWY-5497|MetaCyc: PWY-6696|MetaCyc: PWY-7985 CL1_0794 76de3301482e795264dfd4deea7bc405 670 SUPERFAMILY SSF53706 2 554 3.66E-199 T 30-10-2018 CL1_0794 76de3301482e795264dfd4deea7bc405 670 Gene3D G3DSA:2.40.40.20 540 663 2.8E-34 T 30-10-2018 CL1_0208 ea10888452f62fa8dce9ac35d9cb0ebd 446 SUPERFAMILY SSF55785 324 422 3.14E-8 T 30-10-2018 IPR035965 PAS domain superfamily CL1_0208 ea10888452f62fa8dce9ac35d9cb0ebd 446 Pfam PF01814 Hemerythrin HHE cation binding domain 99 233 1.6E-16 T 30-10-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 CL1_0208 ea10888452f62fa8dce9ac35d9cb0ebd 446 Gene3D G3DSA:3.30.450.20 307 442 4.1E-46 T 30-10-2018 CL1_0208 ea10888452f62fa8dce9ac35d9cb0ebd 446 Pfam PF13596 PAS domain 326 429 2.0E-23 T 30-10-2018 CL1_0208 ea10888452f62fa8dce9ac35d9cb0ebd 446 Gene3D G3DSA:1.20.120.520 87 306 1.4E-53 T 30-10-2018 CL1_0208 ea10888452f62fa8dce9ac35d9cb0ebd 446 Pfam PF04282 Family of unknown function (DUF438) 15 79 3.1E-23 T 30-10-2018 IPR007380 Domain of unknown function DUF438 CL1_1965 d5c18d576c112e42d0867d8c220796d4 209 TIGRFAM TIGR00257 IMPACT_YIGZ: uncharacterized protein, YigZ family 4 198 5.6E-53 T 30-10-2018 IPR015796 Impact family, bacterial/archaeal CL1_1965 d5c18d576c112e42d0867d8c220796d4 209 Pfam PF01205 Uncharacterized protein family UPF0029 17 123 2.9E-32 T 30-10-2018 IPR001498 Impact, N-terminal CL1_1965 d5c18d576c112e42d0867d8c220796d4 209 Gene3D G3DSA:3.30.230.30 2 130 4.2E-47 T 30-10-2018 IPR036956 Impact, N-terminal domain superfamily CL1_1965 d5c18d576c112e42d0867d8c220796d4 209 SUPERFAMILY SSF54980 136 198 6.91E-10 T 30-10-2018 IPR035647 EF-G domain III/V-like CL1_1965 d5c18d576c112e42d0867d8c220796d4 209 Pfam PF09186 Domain of unknown function (DUF1949) 139 194 4.6E-12 T 30-10-2018 IPR015269 Uncharacterised domain UPF0029, Impact, C-terminal CL1_1965 d5c18d576c112e42d0867d8c220796d4 209 ProSitePatterns PS00910 Uncharacterized protein family UPF0029 signature. 78 107 - T 30-10-2018 IPR020569 Uncharacterised protein family UPF0029, Impact, conserved site CL1_1965 d5c18d576c112e42d0867d8c220796d4 209 SUPERFAMILY SSF54211 3 130 9.86E-42 T 30-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CL1_1589 8a8a720443bee95f13d2c065f932d9d5 98 SUPERFAMILY SSF50346 4 79 1.12E-12 T 30-10-2018 IPR011033 PRC-barrel-like superfamily CL1_1589 8a8a720443bee95f13d2c065f932d9d5 98 Gene3D G3DSA:2.30.30.240 4 81 7.0E-6 T 30-10-2018 CL1_1589 8a8a720443bee95f13d2c065f932d9d5 98 Pfam PF05239 PRC-barrel domain 3 82 3.8E-14 T 30-10-2018 IPR027275 PRC-barrel domain CL1_0572 20af63f94ea0eed030e1a83adc1ccf1c 445 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 327 424 6.2E-17 T 30-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CL1_0572 20af63f94ea0eed030e1a83adc1ccf1c 445 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 296 9.0E-57 T 30-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CL1_0572 20af63f94ea0eed030e1a83adc1ccf1c 445 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 2.1E-27 T 30-10-2018 CL1_0572 20af63f94ea0eed030e1a83adc1ccf1c 445 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 98 116 2.1E-27 T 30-10-2018 CL1_0572 20af63f94ea0eed030e1a83adc1ccf1c 445 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 144 162 2.1E-27 T 30-10-2018 CL1_0572 20af63f94ea0eed030e1a83adc1ccf1c 445 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 227 243 2.1E-27 T 30-10-2018 CL1_0572 20af63f94ea0eed030e1a83adc1ccf1c 445 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 253 275 2.1E-27 T 30-10-2018 CL1_0572 20af63f94ea0eed030e1a83adc1ccf1c 445 Gene3D G3DSA:3.50.50.60 107 423 5.7E-119 T 30-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily CL1_0572 20af63f94ea0eed030e1a83adc1ccf1c 445 SUPERFAMILY SSF55424 318 441 3.09E-26 T 30-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 CL1_0572 20af63f94ea0eed030e1a83adc1ccf1c 445 SUPERFAMILY SSF51905 1 306 3.78E-51 T 30-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily CL1_0572 20af63f94ea0eed030e1a83adc1ccf1c 445 Gene3D G3DSA:3.50.50.60 5 333 5.7E-119 T 30-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily CL1_0572 20af63f94ea0eed030e1a83adc1ccf1c 445 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 268 275 3.8E-21 T 30-10-2018 CL1_0572 20af63f94ea0eed030e1a83adc1ccf1c 445 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 228 242 3.8E-21 T 30-10-2018 CL1_0572 20af63f94ea0eed030e1a83adc1ccf1c 445 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 144 169 3.8E-21 T 30-10-2018 CL1_0572 20af63f94ea0eed030e1a83adc1ccf1c 445 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 3.8E-21 T 30-10-2018 CL1_0448 e428fbff72337461d70be1f227c78636 416 Pfam PF04894 Archaeal Nre, N-terminal 19 284 1.9E-102 T 30-10-2018 IPR006978 Archaeal Nre, N-terminal CL1_0448 e428fbff72337461d70be1f227c78636 416 Hamap MF_02096 DNA repair protein. 1 406 40.157 T 30-10-2018 IPR033167 Archaeal Nre GO:0006281 CL1_0448 e428fbff72337461d70be1f227c78636 416 Pfam PF04895 Archaeal Nre, C-terminal 296 406 3.9E-38 T 30-10-2018 IPR006979 Archaeal Nre, C-terminal CL1_1898 7fa2e4cefabfde69f20c0f46498cd7ad 743 Gene3D G3DSA:3.40.50.12370 475 726 3.9E-37 T 30-10-2018 CL1_1898 7fa2e4cefabfde69f20c0f46498cd7ad 743 SUPERFAMILY SSF52402 616 726 5.02E-16 T 30-10-2018 CL1_1898 7fa2e4cefabfde69f20c0f46498cd7ad 743 SUPERFAMILY SSF52402 476 608 5.19E-22 T 30-10-2018 CL1_1898 7fa2e4cefabfde69f20c0f46498cd7ad 743 Gene3D G3DSA:1.20.1740.10 8 473 1.8E-105 T 30-10-2018 CL1_1898 7fa2e4cefabfde69f20c0f46498cd7ad 743 Pfam PF13520 Amino acid permease 13 442 1.4E-50 T 30-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 CL1_1898 7fa2e4cefabfde69f20c0f46498cd7ad 743 PRINTS PR01438 Universal stress protein signature 566 578 3.1E-6 T 30-10-2018 IPR006015 Universal stress protein A CL1_1898 7fa2e4cefabfde69f20c0f46498cd7ad 743 PRINTS PR01438 Universal stress protein signature 584 606 3.1E-6 T 30-10-2018 IPR006015 Universal stress protein A CL1_1898 7fa2e4cefabfde69f20c0f46498cd7ad 743 Pfam PF00582 Universal stress protein family 663 726 5.9E-8 T 30-10-2018 IPR006016 UspA CL1_1898 7fa2e4cefabfde69f20c0f46498cd7ad 743 Pfam PF00582 Universal stress protein family 476 606 9.0E-19 T 30-10-2018 IPR006016 UspA CL1_0898 661dc741be0158c76969d1be6142841c 396 SMART SM00359 2 87 1.8E-23 T 30-10-2018 IPR002478 PUA domain GO:0003723 CL1_0898 661dc741be0158c76969d1be6142841c 396 Gene3D G3DSA:3.40.50.150 179 396 3.6E-71 T 30-10-2018 CL1_0898 661dc741be0158c76969d1be6142841c 396 Gene3D G3DSA:3.30.750.80 72 178 3.1E-37 T 30-10-2018 CL1_0898 661dc741be0158c76969d1be6142841c 396 SUPERFAMILY SSF88697 1 69 1.19E-17 T 30-10-2018 IPR015947 PUA-like superfamily CL1_0898 661dc741be0158c76969d1be6142841c 396 SUPERFAMILY SSF53335 78 389 4.33E-68 T 30-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CL1_0898 661dc741be0158c76969d1be6142841c 396 Gene3D G3DSA:2.30.130.10 1 69 1.8E-21 T 30-10-2018 IPR036974 PUA domain superfamily GO:0003723 CL1_0898 661dc741be0158c76969d1be6142841c 396 Pfam PF10672 S-adenosylmethionine-dependent methyltransferase 169 333 2.2E-20 T 30-10-2018 IPR019614 S-adenosylmethionine-dependent methyltransferase GO:0008168 CL1_0898 661dc741be0158c76969d1be6142841c 396 Pfam PF01472 PUA domain 3 75 3.6E-15 T 30-10-2018 IPR002478 PUA domain GO:0003723 CL1_1052 636f11275bd181690fb61f95fb4ea7fb 354 Gene3D G3DSA:1.10.150.20 40 103 2.2E-25 T 30-10-2018 CL1_1052 636f11275bd181690fb61f95fb4ea7fb 354 Gene3D G3DSA:3.40.50.300 104 354 1.9E-86 T 30-10-2018 CL1_1052 636f11275bd181690fb61f95fb4ea7fb 354 SUPERFAMILY SSF47794 38 98 1.88E-13 T 30-10-2018 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 CL1_1052 636f11275bd181690fb61f95fb4ea7fb 354 Pfam PF08423 Rad51 102 354 5.0E-94 T 30-10-2018 IPR013632 DNA recombination and repair protein Rad51-like, C-terminal Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579 CL1_1052 636f11275bd181690fb61f95fb4ea7fb 354 Pfam PF14520 Helix-hairpin-helix domain 40 95 3.3E-12 T 30-10-2018 CL1_1052 636f11275bd181690fb61f95fb4ea7fb 354 TIGRFAM TIGR02236 recomb_radA: DNA repair and recombination protein RadA 42 354 5.1E-165 T 30-10-2018 IPR011938 DNA recombination/repair protein RadA GO:0003684|GO:0005524|GO:0006281|GO:0006310|GO:0008094 CL1_1052 636f11275bd181690fb61f95fb4ea7fb 354 SMART SM00382 135 324 4.9E-10 T 30-10-2018 IPR003593 AAA+ ATPase domain CL1_1052 636f11275bd181690fb61f95fb4ea7fb 354 Hamap MF_00348 DNA repair and recombination protein RadA [radA]. 39 354 82.132 T 30-10-2018 IPR011938 DNA recombination/repair protein RadA GO:0003684|GO:0005524|GO:0006281|GO:0006310|GO:0008094 CL1_1052 636f11275bd181690fb61f95fb4ea7fb 354 SUPERFAMILY SSF52540 116 353 8.47E-61 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_1052 636f11275bd181690fb61f95fb4ea7fb 354 PIRSF PIRSF005856 29 354 1.7E-137 T 30-10-2018 IPR016467 DNA recombination and repair protein, RecA-like Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579 CL1_1052 636f11275bd181690fb61f95fb4ea7fb 354 SMART SM00278 73 92 360.0 T 30-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CL1_1052 636f11275bd181690fb61f95fb4ea7fb 354 SMART SM00278 40 59 0.011 T 30-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CL1_1087 778a6e635ddaf73f0444c6efd929d54f 325 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 93 112 4.7E-41 T 30-10-2018 IPR017861 Kae1/TsaD family CL1_1087 778a6e635ddaf73f0444c6efd929d54f 325 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 124 136 4.7E-41 T 30-10-2018 IPR017861 Kae1/TsaD family CL1_1087 778a6e635ddaf73f0444c6efd929d54f 325 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 146 167 4.7E-41 T 30-10-2018 IPR017861 Kae1/TsaD family CL1_1087 778a6e635ddaf73f0444c6efd929d54f 325 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 4 17 4.7E-41 T 30-10-2018 IPR017861 Kae1/TsaD family CL1_1087 778a6e635ddaf73f0444c6efd929d54f 325 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 72 92 4.7E-41 T 30-10-2018 IPR017861 Kae1/TsaD family CL1_1087 778a6e635ddaf73f0444c6efd929d54f 325 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 248 257 4.7E-41 T 30-10-2018 IPR017861 Kae1/TsaD family CL1_1087 778a6e635ddaf73f0444c6efd929d54f 325 SUPERFAMILY SSF53067 1 293 2.59E-37 T 30-10-2018 CL1_1087 778a6e635ddaf73f0444c6efd929d54f 325 TIGRFAM TIGR03722 arch_KAE1: universal archaeal protein Kae1 4 324 1.1E-152 T 30-10-2018 IPR022449 tRNA N6-adenosine threonylcarbamoyltransferase Kae1, archaea GO:0000408|GO:0002949 CL1_1087 778a6e635ddaf73f0444c6efd929d54f 325 ProSitePatterns PS01016 Glycoprotease family signature. 92 112 - T 30-10-2018 IPR017860 Peptidase M22, conserved site Reactome: R-HSA-6782315 CL1_1087 778a6e635ddaf73f0444c6efd929d54f 325 Gene3D G3DSA:3.30.420.40 122 278 8.2E-115 T 30-10-2018 CL1_1087 778a6e635ddaf73f0444c6efd929d54f 325 Hamap MF_01446 tRNA N6-adenosine threonylcarbamoyltransferase [kae1]. 1 325 38.076 T 30-10-2018 IPR034680 tRNA N6-adenosine threonylcarbamoyltransferase Kae1/OSGEP GO:0000408|GO:0002949 Reactome: R-HSA-6782315 CL1_1087 778a6e635ddaf73f0444c6efd929d54f 325 Pfam PF00814 Glycoprotease family 22 292 1.5E-96 T 30-10-2018 IPR000905 Gcp-like domain CL1_1087 778a6e635ddaf73f0444c6efd929d54f 325 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 4 291 3.6E-101 T 30-10-2018 IPR017861 Kae1/TsaD family CL1_1087 778a6e635ddaf73f0444c6efd929d54f 325 Gene3D G3DSA:3.30.420.40 4 298 8.2E-115 T 30-10-2018 CL1_1457 516e63069acc9a5d1626b7a2d1d02e48 252 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 30-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CL1_1457 516e63069acc9a5d1626b7a2d1d02e48 252 Pfam PF00005 ABC transporter 19 162 4.9E-30 T 30-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CL1_1457 516e63069acc9a5d1626b7a2d1d02e48 252 SMART SM00382 28 211 2.6E-9 T 30-10-2018 IPR003593 AAA+ ATPase domain CL1_1457 516e63069acc9a5d1626b7a2d1d02e48 252 SUPERFAMILY SSF52540 3 226 4.42E-61 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_1457 516e63069acc9a5d1626b7a2d1d02e48 252 Gene3D G3DSA:3.40.50.300 1 244 2.8E-67 T 30-10-2018 CL1_0896 a4aac396680d62ac26925123cb0cd3a1 404 Pfam PF01546 Peptidase family M20/M25/M40 79 402 1.0E-37 T 30-10-2018 IPR002933 Peptidase M20 GO:0016787 CL1_0896 a4aac396680d62ac26925123cb0cd3a1 404 Pfam PF07687 Peptidase dimerisation domain 189 300 2.3E-20 T 30-10-2018 IPR011650 Peptidase M20, dimerisation domain CL1_0896 a4aac396680d62ac26925123cb0cd3a1 404 Gene3D G3DSA:3.40.630.10 7 392 8.6E-80 T 30-10-2018 CL1_0896 a4aac396680d62ac26925123cb0cd3a1 404 SUPERFAMILY SSF53187 1 402 1.11E-59 T 30-10-2018 CL1_0896 a4aac396680d62ac26925123cb0cd3a1 404 TIGRFAM TIGR01910 DapE-ArgE: peptidase, ArgE/DapE family 2 397 3.2E-79 T 30-10-2018 IPR010182 N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine deformylase/Succinyl-diaminopimelate desuccinylase CL1_0896 a4aac396680d62ac26925123cb0cd3a1 404 Gene3D G3DSA:3.30.70.360 192 324 8.6E-80 T 30-10-2018 CL1_0896 a4aac396680d62ac26925123cb0cd3a1 404 SUPERFAMILY SSF55031 194 304 5.08E-19 T 30-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain CL1_1271 d57571bea80e5ddf94df38c670920a65 169 SUPERFAMILY SSF46785 64 163 5.46E-22 T 30-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CL1_1271 d57571bea80e5ddf94df38c670920a65 169 Pfam PF01022 Bacterial regulatory protein, arsR family 76 120 3.0E-11 T 30-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CL1_1271 d57571bea80e5ddf94df38c670920a65 169 SMART SM00418 68 148 1.4E-19 T 30-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CL1_1271 d57571bea80e5ddf94df38c670920a65 169 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 70 85 1.2E-10 T 30-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CL1_1271 d57571bea80e5ddf94df38c670920a65 169 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 117 132 1.2E-10 T 30-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CL1_1271 d57571bea80e5ddf94df38c670920a65 169 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 102 117 1.2E-10 T 30-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CL1_1271 d57571bea80e5ddf94df38c670920a65 169 Gene3D G3DSA:1.10.10.10 63 148 1.9E-21 T 30-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CL1_1271 d57571bea80e5ddf94df38c670920a65 169 Pfam PF13412 Winged helix-turn-helix DNA-binding 6 46 6.7E-11 T 30-10-2018 CL1_1271 d57571bea80e5ddf94df38c670920a65 169 Gene3D G3DSA:1.10.10.10 1 62 1.3E-15 T 30-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CL1_1271 d57571bea80e5ddf94df38c670920a65 169 SUPERFAMILY SSF46785 3 58 8.67E-11 T 30-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CL1_0345 72360a95bb95c5262425dc26d05c6eca 406 ProSitePatterns PS00318 Hydroxymethylglutaryl-coenzyme A reductases signature 2. 338 345 - T 30-10-2018 IPR023076 Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CL1_0345 72360a95bb95c5262425dc26d05c6eca 406 Gene3D G3DSA:1.10.3270.10 1 72 5.1E-7 T 30-10-2018 IPR023282 Hydroxymethylglutaryl-CoA reductase, N-terminal GO:0004420 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CL1_0345 72360a95bb95c5262425dc26d05c6eca 406 ProSitePatterns PS00066 Hydroxymethylglutaryl-coenzyme A reductases signature 1. 185 199 - T 30-10-2018 IPR023076 Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CL1_0345 72360a95bb95c5262425dc26d05c6eca 406 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 93 113 2.6E-59 T 30-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CL1_0345 72360a95bb95c5262425dc26d05c6eca 406 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 183 201 2.6E-59 T 30-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CL1_0345 72360a95bb95c5262425dc26d05c6eca 406 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 326 347 2.6E-59 T 30-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CL1_0345 72360a95bb95c5262425dc26d05c6eca 406 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 223 248 2.6E-59 T 30-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CL1_0345 72360a95bb95c5262425dc26d05c6eca 406 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 62 83 2.6E-59 T 30-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CL1_0345 72360a95bb95c5262425dc26d05c6eca 406 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 274 300 2.6E-59 T 30-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CL1_0345 72360a95bb95c5262425dc26d05c6eca 406 SUPERFAMILY SSF55035 127 242 4.45E-40 T 30-10-2018 IPR009023 Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain superfamily GO:0050662 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CL1_0345 72360a95bb95c5262425dc26d05c6eca 406 Pfam PF00368 Hydroxymethylglutaryl-coenzyme A reductase 30 406 3.8E-142 T 30-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CL1_0345 72360a95bb95c5262425dc26d05c6eca 406 TIGRFAM TIGR00533 HMG_CoA_R_NADP: hydroxymethylglutaryl-CoA reductase (NADPH) 1 406 1.5E-169 T 30-10-2018 IPR004554 Hydroxymethylglutaryl-CoA reductase, eukaryotic/archaeal type GO:0004420|GO:0008299|GO:0016021|GO:0050661|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CL1_0345 72360a95bb95c5262425dc26d05c6eca 406 Gene3D G3DSA:3.30.70.420 127 242 1.5E-133 T 30-10-2018 IPR009023 Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain superfamily GO:0050662 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CL1_0345 72360a95bb95c5262425dc26d05c6eca 406 Gene3D G3DSA:3.90.770.10 73 393 1.5E-133 T 30-10-2018 IPR023074 Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic domain superfamily GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CL1_0345 72360a95bb95c5262425dc26d05c6eca 406 SUPERFAMILY SSF56542 3 396 1.44E-92 T 30-10-2018 IPR009029 Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding domain superfamily GO:0015936|GO:0016616|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CL1_0103 35f8a55800ce4323fbd772023c898c0d 330 Gene3D G3DSA:3.30.1330.10 4 146 2.0E-23 T 30-10-2018 IPR036921 PurM-like, N-terminal domain superfamily CL1_0103 35f8a55800ce4323fbd772023c898c0d 330 SUPERFAMILY SSF56042 152 314 2.54E-28 T 30-10-2018 IPR036676 PurM-like, C-terminal domain superfamily CL1_0103 35f8a55800ce4323fbd772023c898c0d 330 SUPERFAMILY SSF55326 6 147 6.45E-22 T 30-10-2018 IPR036921 PurM-like, N-terminal domain superfamily CL1_0103 35f8a55800ce4323fbd772023c898c0d 330 Gene3D G3DSA:3.90.650.10 152 321 1.5E-31 T 30-10-2018 IPR036676 PurM-like, C-terminal domain superfamily CL1_0103 35f8a55800ce4323fbd772023c898c0d 330 Pfam PF00586 AIR synthase related protein, N-terminal domain 49 143 3.0E-14 T 30-10-2018 IPR016188 PurM-like, N-terminal domain CL1_0103 35f8a55800ce4323fbd772023c898c0d 330 PIRSF PIRSF005644 1 329 2.8E-61 T 30-10-2018 IPR011854 Carbamoyl dehydratase HypE CL1_0103 35f8a55800ce4323fbd772023c898c0d 330 Pfam PF02769 AIR synthase related protein, C-terminal domain 154 305 5.9E-16 T 30-10-2018 IPR010918 PurM-like, C-terminal domain CL1_1623 711870d9ef1ad3d0374abb83d2d75627 64 Gene3D G3DSA:4.10.1150.10 1 64 1.2E-9 T 30-10-2018 IPR024069 AF2212-like domain superfamily CL1_1623 711870d9ef1ad3d0374abb83d2d75627 64 Pfam PF01954 Protein of unknown function DUF104 1 57 1.7E-15 T 30-10-2018 IPR008203 Uncharacterised protein family UPF0165 CL1_1623 711870d9ef1ad3d0374abb83d2d75627 64 SUPERFAMILY SSF141694 1 40 2.62E-11 T 30-10-2018 CL1_1746 f2d3fa1d53eff1d4f0a27e497e08874d 597 Gene3D G3DSA:2.40.30.10 228 338 5.8E-41 T 30-10-2018 CL1_1746 f2d3fa1d53eff1d4f0a27e497e08874d 597 SUPERFAMILY SSF52540 5 288 6.5E-55 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_1746 f2d3fa1d53eff1d4f0a27e497e08874d 597 SUPERFAMILY SSF50447 465 589 1.96E-24 T 30-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily CL1_1746 f2d3fa1d53eff1d4f0a27e497e08874d 597 Pfam PF14578 Elongation factor Tu domain 4 467 553 2.6E-29 T 30-10-2018 IPR029459 Elongation factor Tu-type domain CL1_1746 f2d3fa1d53eff1d4f0a27e497e08874d 597 Pfam PF03144 Elongation factor Tu domain 2 247 325 7.5E-13 T 30-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CL1_1746 f2d3fa1d53eff1d4f0a27e497e08874d 597 Hamap MF_00100_A Translation initiation factor IF-2 [infB]. 2 596 43.562 T 30-10-2018 IPR004544 Translation initiation factor aIF-2, archaea GO:0003743|GO:0005525|GO:0005622|GO:0006413 CL1_1746 f2d3fa1d53eff1d4f0a27e497e08874d 597 SUPERFAMILY SSF52156 334 460 1.29E-34 T 30-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily CL1_1746 f2d3fa1d53eff1d4f0a27e497e08874d 597 Gene3D G3DSA:3.40.50.300 1 227 1.5E-65 T 30-10-2018 CL1_1746 f2d3fa1d53eff1d4f0a27e497e08874d 597 TIGRFAM TIGR00491 aIF-2: translation initiation factor aIF-2 3 594 2.6E-241 T 30-10-2018 IPR004544 Translation initiation factor aIF-2, archaea GO:0003743|GO:0005525|GO:0005622|GO:0006413 CL1_1746 f2d3fa1d53eff1d4f0a27e497e08874d 597 Gene3D G3DSA:2.40.30.10 466 556 2.6E-30 T 30-10-2018 CL1_1746 f2d3fa1d53eff1d4f0a27e497e08874d 597 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 8 156 6.0E-20 T 30-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CL1_1746 f2d3fa1d53eff1d4f0a27e497e08874d 597 Gene3D G3DSA:3.40.50.10050 349 457 2.3E-36 T 30-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily CL1_1746 f2d3fa1d53eff1d4f0a27e497e08874d 597 Pfam PF00009 Elongation factor Tu GTP binding domain 8 214 2.2E-32 T 30-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CL1_1746 f2d3fa1d53eff1d4f0a27e497e08874d 597 PRINTS PR00315 GTP-binding elongation factor signature 8 21 1.8E-10 T 30-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CL1_1746 f2d3fa1d53eff1d4f0a27e497e08874d 597 PRINTS PR00315 GTP-binding elongation factor signature 90 101 1.8E-10 T 30-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CL1_1746 f2d3fa1d53eff1d4f0a27e497e08874d 597 PRINTS PR00315 GTP-binding elongation factor signature 126 135 1.8E-10 T 30-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CL1_1746 f2d3fa1d53eff1d4f0a27e497e08874d 597 PRINTS PR00315 GTP-binding elongation factor signature 74 84 1.8E-10 T 30-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CL1_1746 f2d3fa1d53eff1d4f0a27e497e08874d 597 Pfam PF11987 Translation-initiation factor 2 351 446 7.7E-24 T 30-10-2018 IPR023115 Translation initiation factor IF- 2, domain 3 CL1_0307 0b8af3d5c3a6e98d0302b86ae26df3bc 626 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 35 602 29.138 T 30-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CL1_0307 0b8af3d5c3a6e98d0302b86ae26df3bc 626 SUPERFAMILY SSF52954 504 606 2.72E-32 T 30-10-2018 CL1_0307 0b8af3d5c3a6e98d0302b86ae26df3bc 626 Pfam PF08915 Archaea-specific editing domain of threonyl-tRNA synthetase 1 139 9.0E-56 T 30-10-2018 IPR015011 Threonyl-tRNA synthetase, editing domain, archaea GO:0004829|GO:0005524|GO:0005737|GO:0008270 KEGG: 00970+6.1.1.3 CL1_0307 0b8af3d5c3a6e98d0302b86ae26df3bc 626 Gene3D G3DSA:3.30.930.10 203 494 6.4E-62 T 30-10-2018 CL1_0307 0b8af3d5c3a6e98d0302b86ae26df3bc 626 SUPERFAMILY SSF55681 207 489 2.11E-57 T 30-10-2018 CL1_0307 0b8af3d5c3a6e98d0302b86ae26df3bc 626 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 288 492 2.0E-19 T 30-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CL1_0307 0b8af3d5c3a6e98d0302b86ae26df3bc 626 Gene3D G3DSA:3.50.80.10 1 139 9.6E-58 T 30-10-2018 IPR023509 D-aminoacyl-tRNA deacylase-like superfamily CL1_0307 0b8af3d5c3a6e98d0302b86ae26df3bc 626 PRINTS PR01047 Threonyl-tRNA synthetase signature 428 456 1.6E-32 T 30-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CL1_0307 0b8af3d5c3a6e98d0302b86ae26df3bc 626 PRINTS PR01047 Threonyl-tRNA synthetase signature 506 518 1.6E-32 T 30-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CL1_0307 0b8af3d5c3a6e98d0302b86ae26df3bc 626 PRINTS PR01047 Threonyl-tRNA synthetase signature 471 484 1.6E-32 T 30-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CL1_0307 0b8af3d5c3a6e98d0302b86ae26df3bc 626 PRINTS PR01047 Threonyl-tRNA synthetase signature 294 322 1.6E-32 T 30-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CL1_0307 0b8af3d5c3a6e98d0302b86ae26df3bc 626 PRINTS PR01047 Threonyl-tRNA synthetase signature 328 351 1.6E-32 T 30-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CL1_0307 0b8af3d5c3a6e98d0302b86ae26df3bc 626 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 26 603 7.7E-175 T 30-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CL1_0307 0b8af3d5c3a6e98d0302b86ae26df3bc 626 Pfam PF03129 Anticodon binding domain 513 602 9.4E-26 T 30-10-2018 IPR004154 Anticodon-binding CL1_0307 0b8af3d5c3a6e98d0302b86ae26df3bc 626 ProDom PD016189 SYNTHETASE LIGASE THREONYL-TRNA AMINOACYL-TRNA NUCLEOTIDE-BINDING BIOSYNTHESIS ATP-BINDING ZINC METAL-BINDING THRRS 1 139 1.0E-66 T 30-10-2018 IPR015011 Threonyl-tRNA synthetase, editing domain, archaea GO:0004829|GO:0005524|GO:0005737|GO:0008270 KEGG: 00970+6.1.1.3 CL1_0307 0b8af3d5c3a6e98d0302b86ae26df3bc 626 Gene3D G3DSA:3.40.50.800 504 607 1.6E-34 T 30-10-2018 IPR036621 Anticodon-binding domain superfamily CL1_0963 cbe52ef0a197eec0d0e3783015601e2c 437 Pfam PF03129 Anticodon binding domain 342 431 3.0E-19 T 30-10-2018 IPR004154 Anticodon-binding CL1_0963 cbe52ef0a197eec0d0e3783015601e2c 437 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 7 422 2.3E-126 T 30-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 CL1_0963 cbe52ef0a197eec0d0e3783015601e2c 437 SUPERFAMILY SSF52954 332 435 1.31E-22 T 30-10-2018 CL1_0963 cbe52ef0a197eec0d0e3783015601e2c 437 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 3 433 31.127 T 30-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 CL1_0963 cbe52ef0a197eec0d0e3783015601e2c 437 SUPERFAMILY SSF55681 7 332 2.19E-87 T 30-10-2018 CL1_0963 cbe52ef0a197eec0d0e3783015601e2c 437 PIRSF PIRSF001549 1 434 4.5E-140 T 30-10-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 CL1_0963 cbe52ef0a197eec0d0e3783015601e2c 437 Pfam PF13393 Histidyl-tRNA synthetase 10 324 4.7E-66 T 30-10-2018 CL1_0963 cbe52ef0a197eec0d0e3783015601e2c 437 Gene3D G3DSA:3.30.930.10 1 329 4.7E-110 T 30-10-2018 CL1_0963 cbe52ef0a197eec0d0e3783015601e2c 437 TIGRFAM TIGR00443 hisZ_biosyn_reg: ATP phosphoribosyltransferase, regulatory subunit 12 327 8.8E-85 T 30-10-2018 IPR004517 ATP phosphoribosyltransferase regulatory subunit GO:0000105|GO:0005737 CL1_0963 cbe52ef0a197eec0d0e3783015601e2c 437 Hamap MF_00125 ATP phosphoribosyltransferase regulatory subunit [hisZ]. 17 384 26.279 T 30-10-2018 IPR004517 ATP phosphoribosyltransferase regulatory subunit GO:0000105|GO:0005737 CL1_0963 cbe52ef0a197eec0d0e3783015601e2c 437 Gene3D G3DSA:3.40.50.800 339 433 4.7E-24 T 30-10-2018 IPR036621 Anticodon-binding domain superfamily CL1_0295 3eaa9da0764d38e860a261a27f6494e6 493 Pfam PF02386 Cation transport protein 65 480 1.6E-68 T 30-10-2018 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 CL1_0295 3eaa9da0764d38e860a261a27f6494e6 493 TIGRFAM TIGR00933 2a38: potassium uptake protein, TrkH family 95 469 8.6E-111 T 30-10-2018 IPR004772 TrkH potassium transport family GO:0015379|GO:0016021|GO:0071805 CL1_0587 58feb0d458399f58eb6148d8b56ab673 341 PRINTS PR00148 Enolase signature 92 108 1.7E-5 T 30-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CL1_0587 58feb0d458399f58eb6148d8b56ab673 341 PRINTS PR00148 Enolase signature 316 330 1.7E-5 T 30-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CL1_0587 58feb0d458399f58eb6148d8b56ab673 341 Pfam PF03952 Enolase, N-terminal domain 38 119 3.4E-23 T 30-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CL1_0587 58feb0d458399f58eb6148d8b56ab673 341 SMART SM01192 124 340 8.2E-13 T 30-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CL1_0587 58feb0d458399f58eb6148d8b56ab673 341 SMART SM01193 4 119 2.0E-35 T 30-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CL1_0587 58feb0d458399f58eb6148d8b56ab673 341 Gene3D G3DSA:3.20.20.120 223 339 5.0E-13 T 30-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily CL1_0587 58feb0d458399f58eb6148d8b56ab673 341 Gene3D G3DSA:3.30.390.10 1 111 1.6E-21 T 30-10-2018 IPR029017 Enolase-like, N-terminal CL1_0587 58feb0d458399f58eb6148d8b56ab673 341 SUPERFAMILY SSF54826 1 123 1.68E-30 T 30-10-2018 CL1_0587 58feb0d458399f58eb6148d8b56ab673 341 SUPERFAMILY SSF51604 126 337 1.79E-28 T 30-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily CL1_0587 58feb0d458399f58eb6148d8b56ab673 341 Pfam PF00113 Enolase, C-terminal TIM barrel domain 247 334 8.6E-8 T 30-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CL1_0248 b765e808f43b49ca5bc58e9740e940e1 411 Pfam PF10143 2,3-bisphosphoglycerate-independent phosphoglycerate mutase 40 208 5.2E-54 T 30-10-2018 IPR004456 2,3-bisphosphoglycerate-independent phosphoglycerate mutase GO:0003824|GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CL1_0248 b765e808f43b49ca5bc58e9740e940e1 411 Gene3D G3DSA:3.40.720.10 7 397 2.9E-141 T 30-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 CL1_0248 b765e808f43b49ca5bc58e9740e940e1 411 TIGRFAM TIGR00306 apgM: phosphoglycerate mutase (2,3-diphosphoglycerate-independent), archaeal form 7 401 1.5E-136 T 30-10-2018 IPR004456 2,3-bisphosphoglycerate-independent phosphoglycerate mutase GO:0003824|GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CL1_0248 b765e808f43b49ca5bc58e9740e940e1 411 Hamap MF_01402_A 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [apgM]. 4 402 45.532 T 30-10-2018 IPR023665 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, prokaryotes GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CL1_0248 b765e808f43b49ca5bc58e9740e940e1 411 Pfam PF01676 Metalloenzyme superfamily 5 400 1.4E-55 T 30-10-2018 IPR006124 Metalloenzyme GO:0003824|GO:0046872 CL1_0248 b765e808f43b49ca5bc58e9740e940e1 411 Gene3D G3DSA:3.30.70.2130 81 230 2.9E-141 T 30-10-2018 CL1_0248 b765e808f43b49ca5bc58e9740e940e1 411 PIRSF PIRSF006392 1 407 1.2E-154 T 30-10-2018 IPR004456 2,3-bisphosphoglycerate-independent phosphoglycerate mutase GO:0003824|GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CL1_0248 b765e808f43b49ca5bc58e9740e940e1 411 SUPERFAMILY SSF53649 4 404 8.21E-44 T 30-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 CL1_0144 78cb1889e5c0681ad22e8c7aafe7234a 428 Gene3D G3DSA:1.10.645.10 6 424 1.9E-105 T 30-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CL1_0144 78cb1889e5c0681ad22e8c7aafe7234a 428 Pfam PF00374 Nickel-dependent hydrogenase 252 424 3.8E-10 T 30-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 CL1_0144 78cb1889e5c0681ad22e8c7aafe7234a 428 Pfam PF00374 Nickel-dependent hydrogenase 43 128 5.3E-12 T 30-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 CL1_0144 78cb1889e5c0681ad22e8c7aafe7234a 428 SUPERFAMILY SSF56762 8 424 3.27E-95 T 30-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CL1_0144 78cb1889e5c0681ad22e8c7aafe7234a 428 ProSitePatterns PS00508 Nickel-dependent hydrogenases large subunit signature 2. 415 424 - T 30-10-2018 IPR018194 Nickel-dependent hydrogenase, large subunit, nickel binding site GO:0008901|GO:0016151|GO:0055114 CL1_0486 46aeeebbcb5e62c845dbdcd4269c69ab 370 Gene3D G3DSA:3.40.50.11750 18 263 6.0E-110 T 30-10-2018 CL1_0486 46aeeebbcb5e62c845dbdcd4269c69ab 370 Pfam PF01924 Hydrogenase formation hypA family 13 367 5.1E-134 T 30-10-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 CL1_0486 46aeeebbcb5e62c845dbdcd4269c69ab 370 Gene3D G3DSA:3.40.50.11740 62 303 6.0E-110 T 30-10-2018 CL1_0486 46aeeebbcb5e62c845dbdcd4269c69ab 370 TIGRFAM TIGR00075 hypD: hydrogenase expression/formation protein HypD 6 367 7.4E-130 T 30-10-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 CL1_0486 46aeeebbcb5e62c845dbdcd4269c69ab 370 PIRSF PIRSF005622 2 370 2.6E-142 T 30-10-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 CL1_0486 46aeeebbcb5e62c845dbdcd4269c69ab 370 Gene3D G3DSA:1.10.10.2140 318 370 6.1E-25 T 30-10-2018 CL1_1942 7900514fe3e79d3f73c6eb5eea6a1b38 508 SUPERFAMILY SSF56300 2 234 8.02E-50 T 30-10-2018 CL1_1942 7900514fe3e79d3f73c6eb5eea6a1b38 508 Gene3D G3DSA:3.60.21.10 1 247 1.2E-39 T 30-10-2018 IPR029052 Metallo-dependent phosphatase-like CL1_1942 7900514fe3e79d3f73c6eb5eea6a1b38 508 Gene3D G3DSA:3.60.21.10 257 493 8.8E-22 T 30-10-2018 IPR029052 Metallo-dependent phosphatase-like CL1_1942 7900514fe3e79d3f73c6eb5eea6a1b38 508 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 282 472 9.0E-8 T 30-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 CL1_1942 7900514fe3e79d3f73c6eb5eea6a1b38 508 Pfam PF00149 Calcineurin-like phosphoesterase 2 185 2.2E-20 T 30-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CL1_1942 7900514fe3e79d3f73c6eb5eea6a1b38 508 SUPERFAMILY SSF56300 272 484 2.28E-30 T 30-10-2018 CL1_1386 4ced5f4c1667f729c2ccc920440494b4 150 Pfam PF01037 Lrp/AsnC ligand binding domain 71 140 1.8E-17 T 30-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CL1_1386 4ced5f4c1667f729c2ccc920440494b4 150 SUPERFAMILY SSF46785 5 65 6.75E-18 T 30-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CL1_1386 4ced5f4c1667f729c2ccc920440494b4 150 Gene3D G3DSA:3.30.70.920 57 150 3.3E-26 T 30-10-2018 CL1_1386 4ced5f4c1667f729c2ccc920440494b4 150 SUPERFAMILY SSF54909 65 150 4.16E-21 T 30-10-2018 IPR011008 Dimeric alpha-beta barrel CL1_1386 4ced5f4c1667f729c2ccc920440494b4 150 Pfam PF13404 AsnC-type helix-turn-helix domain 5 46 1.0E-17 T 30-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 CL1_1386 4ced5f4c1667f729c2ccc920440494b4 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 32 51 7.1E-17 T 30-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 CL1_1386 4ced5f4c1667f729c2ccc920440494b4 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 5 21 7.1E-17 T 30-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 CL1_1386 4ced5f4c1667f729c2ccc920440494b4 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 21 32 7.1E-17 T 30-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 CL1_1386 4ced5f4c1667f729c2ccc920440494b4 150 Gene3D G3DSA:1.10.10.10 2 55 3.6E-23 T 30-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CL1_1386 4ced5f4c1667f729c2ccc920440494b4 150 SMART SM00344 5 111 2.3E-48 T 30-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CL1_0565 ff75d7d24a52676e3dc90e68ba8c027c 444 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 375 425 1.4E-13 T 30-10-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain CL1_0565 ff75d7d24a52676e3dc90e68ba8c027c 444 Gene3D G3DSA:3.60.15.10 3 443 6.3E-134 T 30-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like CL1_0565 ff75d7d24a52676e3dc90e68ba8c027c 444 ProSitePatterns PS01292 Uncharacterized protein family UPF0036 signature. 382 410 - T 30-10-2018 IPR001587 Ribonuclease J, conserved site CL1_0565 ff75d7d24a52676e3dc90e68ba8c027c 444 SUPERFAMILY SSF56281 2 443 4.06E-63 T 30-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like CL1_0565 ff75d7d24a52676e3dc90e68ba8c027c 444 SMART SM00849 14 225 2.4E-20 T 30-10-2018 IPR001279 Metallo-beta-lactamase CL1_0565 ff75d7d24a52676e3dc90e68ba8c027c 444 Gene3D G3DSA:3.40.50.10710 219 378 6.3E-134 T 30-10-2018 CL1_0565 ff75d7d24a52676e3dc90e68ba8c027c 444 Pfam PF00753 Metallo-beta-lactamase superfamily 16 187 6.4E-13 T 30-10-2018 IPR001279 Metallo-beta-lactamase CL1_0565 ff75d7d24a52676e3dc90e68ba8c027c 444 TIGRFAM TIGR00649 MG423: beta-CASP ribonuclease, RNase J family 2 443 1.9E-156 T 30-10-2018 IPR004613 Ribonuclease J GO:0003723|GO:0046872 CL1_0565 ff75d7d24a52676e3dc90e68ba8c027c 444 Hamap MF_01492 Ribonuclease J [rnj]. 1 444 49.034 T 30-10-2018 IPR030879 Ribonuclease J, archaea GO:0003723|GO:0004534|GO:0090503 CL1_1040 a09e417d172ba00558916f1ce6412191 457 SUPERFAMILY SSF51011 384 457 1.73E-38 T 30-10-2018 CL1_1040 a09e417d172ba00558916f1ce6412191 457 Pfam PF00128 Alpha amylase, catalytic domain 52 201 1.6E-10 T 30-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CL1_1040 a09e417d172ba00558916f1ce6412191 457 SMART SM00642 32 377 6.0E-26 T 30-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CL1_1040 a09e417d172ba00558916f1ce6412191 457 Pfam PF09154 Domain of unknown function (DUF1939) 386 452 1.1E-21 T 30-10-2018 IPR015237 Alpha-amylase C-terminal, prokaryotic GO:0004553 CL1_1040 a09e417d172ba00558916f1ce6412191 457 Gene3D G3DSA:2.60.40.1180 360 457 4.9E-52 T 30-10-2018 IPR013780 Glycosyl hydrolase, all-beta CL1_1040 a09e417d172ba00558916f1ce6412191 457 Gene3D G3DSA:3.20.20.80 24 359 2.6E-108 T 30-10-2018 CL1_1040 a09e417d172ba00558916f1ce6412191 457 PIRSF PIRSF001021 5 457 3.3E-117 T 30-10-2018 IPR013776 Alpha-amylase, thermostable GO:0004553|GO:0005509|GO:0005975 KEGG: 00500+3.2.1.1 CL1_1040 a09e417d172ba00558916f1ce6412191 457 SUPERFAMILY SSF51445 29 381 3.39E-73 T 30-10-2018 IPR017853 Glycoside hydrolase superfamily CL1_1718 2efb77a8241a4ddeb3779debcbfbdb60 615 Pfam PF08308 PEGA domain 265 332 1.4E-16 T 30-10-2018 IPR013229 PEGA CL1_1718 2efb77a8241a4ddeb3779debcbfbdb60 615 Pfam PF08308 PEGA domain 196 263 2.1E-19 T 30-10-2018 IPR013229 PEGA CL1_1718 2efb77a8241a4ddeb3779debcbfbdb60 615 Pfam PF08308 PEGA domain 334 401 2.7E-23 T 30-10-2018 IPR013229 PEGA CL1_1718 2efb77a8241a4ddeb3779debcbfbdb60 615 Pfam PF08308 PEGA domain 404 471 5.2E-16 T 30-10-2018 IPR013229 PEGA CL1_1718 2efb77a8241a4ddeb3779debcbfbdb60 615 Pfam PF08308 PEGA domain 127 192 4.4E-19 T 30-10-2018 IPR013229 PEGA CL1_1718 2efb77a8241a4ddeb3779debcbfbdb60 615 Gene3D G3DSA:2.60.40.1120 337 402 2.9E-5 T 30-10-2018 CL1_0766 117cc333b6fe737c21f145307562e8fd 741 Gene3D G3DSA:1.50.10.20 385 529 1.0E-12 T 30-10-2018 CL1_0766 117cc333b6fe737c21f145307562e8fd 741 Gene3D G3DSA:1.50.10.20 40 105 1.1E-7 T 30-10-2018 CL1_0766 117cc333b6fe737c21f145307562e8fd 741 SUPERFAMILY SSF48239 25 291 7.07E-24 T 30-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid CL1_0766 117cc333b6fe737c21f145307562e8fd 741 SUPERFAMILY SSF48239 309 513 3.37E-20 T 30-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid CL1_0766 117cc333b6fe737c21f145307562e8fd 741 Gene3D G3DSA:1.50.10.20 106 184 1.8E-7 T 30-10-2018 CL1_0766 117cc333b6fe737c21f145307562e8fd 741 Gene3D G3DSA:1.50.10.20 198 384 1.3E-11 T 30-10-2018 CL1_0766 117cc333b6fe737c21f145307562e8fd 741 Pfam PF00432 Prenyltransferase and squalene oxidase repeat 72 102 0.033 T 30-10-2018 IPR001330 PFTB repeat GO:0003824 CL1_0766 117cc333b6fe737c21f145307562e8fd 741 Pfam PF00432 Prenyltransferase and squalene oxidase repeat 311 341 6.7E-4 T 30-10-2018 IPR001330 PFTB repeat GO:0003824 CL1_0617 d5207fd210ef559a8e056eddb21d7c50 141 SMART SM01374 20 141 2.4E-56 T 30-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CL1_0617 d5207fd210ef559a8e056eddb21d7c50 141 TIGRFAM TIGR03673 uL14_arch: 50S ribosomal protein uL14 15 140 2.3E-60 T 30-10-2018 IPR019971 Ribosomal protein L14P, archaeal CL1_0617 d5207fd210ef559a8e056eddb21d7c50 141 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 20 141 19.619 T 30-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CL1_0617 d5207fd210ef559a8e056eddb21d7c50 141 Gene3D G3DSA:2.40.150.20 1 140 5.8E-49 T 30-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 CL1_0617 d5207fd210ef559a8e056eddb21d7c50 141 SUPERFAMILY SSF50193 16 141 4.45E-44 T 30-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 CL1_0617 d5207fd210ef559a8e056eddb21d7c50 141 Pfam PF00238 Ribosomal protein L14p/L23e 24 140 1.5E-34 T 30-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CL1_1324 1d1754afa6f5904d5a7bc0ac7d0888e5 279 Gene3D G3DSA:3.40.50.2020 17 138 9.3E-83 T 30-10-2018 CL1_1324 1d1754afa6f5904d5a7bc0ac7d0888e5 279 Gene3D G3DSA:3.40.50.2020 139 263 9.3E-83 T 30-10-2018 CL1_1324 1d1754afa6f5904d5a7bc0ac7d0888e5 279 SMART SM01400 1 110 5.0E-37 T 30-10-2018 CL1_1324 1d1754afa6f5904d5a7bc0ac7d0888e5 279 Hamap MF_00583_A Putative ribose-phosphate pyrophosphokinase [prs]. 1 278 36.83 T 30-10-2018 IPR037514 Ribose-phosphate pyrophosphokinase, archaea GO:0004749 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CL1_1324 1d1754afa6f5904d5a7bc0ac7d0888e5 279 SUPERFAMILY SSF53271 62 271 1.01E-39 T 30-10-2018 IPR029057 Phosphoribosyltransferase-like CL1_1324 1d1754afa6f5904d5a7bc0ac7d0888e5 279 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 2 109 4.6E-22 T 30-10-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CL1_1324 1d1754afa6f5904d5a7bc0ac7d0888e5 279 Pfam PF00156 Phosphoribosyl transferase domain 141 239 4.9E-19 T 30-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CL1_1324 1d1754afa6f5904d5a7bc0ac7d0888e5 279 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 1 274 7.9E-92 T 30-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CL1_0381 fa386611b829b30b0e578d8b0c35d45a 326 Hamap MF_01470 CRISPR-associated endonuclease Cas1 [cas1]. 3 311 25.217 T 30-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 CL1_0381 fa386611b829b30b0e578d8b0c35d45a 326 TIGRFAM TIGR00287 cas1: CRISPR-associated endonuclease Cas1 6 320 7.2E-95 T 30-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 CL1_0381 fa386611b829b30b0e578d8b0c35d45a 326 Gene3D G3DSA:1.20.120.920 83 326 1.2E-64 T 30-10-2018 CL1_0381 fa386611b829b30b0e578d8b0c35d45a 326 Pfam PF01867 CRISPR associated protein Cas1 8 281 1.3E-83 T 30-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 CL1_0381 fa386611b829b30b0e578d8b0c35d45a 326 Gene3D G3DSA:3.100.10.20 1 82 3.4E-30 T 30-10-2018 CL1_0381 fa386611b829b30b0e578d8b0c35d45a 326 TIGRFAM TIGR03641 cas1_HMARI: CRISPR-associated endonuclease Cas1, subtype I-B/HMARI/TNEAP 5 325 2.5E-130 T 30-10-2018 IPR019858 CRISPR-associated protein Cas1, HMARI/TNEAP subtype GO:0004520|GO:0043571|GO:0046872 CL1_1313 29a6d86887325698b8408f3f73f57ef9 1473 Pfam PF08542 Replication factor C C-terminal domain 1382 1467 1.8E-21 T 30-10-2018 IPR013748 Replication factor C, C-terminal Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-176187|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804756|Reactome: R-HSA-69091|Reactome: R-HSA-69473 CL1_1313 29a6d86887325698b8408f3f73f57ef9 1473 Gene3D G3DSA:3.10.28.10 977 1148 1.9E-19 T 30-10-2018 IPR027434 Homing endonuclease CL1_1313 29a6d86887325698b8408f3f73f57ef9 1473 Gene3D G3DSA:3.10.28.10 180 343 4.0E-26 T 30-10-2018 IPR027434 Homing endonuclease CL1_1313 29a6d86887325698b8408f3f73f57ef9 1473 Gene3D G3DSA:2.170.16.10 691 826 6.0E-16 T 30-10-2018 CL1_1313 29a6d86887325698b8408f3f73f57ef9 1473 SUPERFAMILY SSF55608 272 360 3.57E-15 T 30-10-2018 IPR027434 Homing endonuclease CL1_1313 29a6d86887325698b8408f3f73f57ef9 1473 Gene3D G3DSA:1.10.10.10 827 976 6.4E-8 T 30-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CL1_1313 29a6d86887325698b8408f3f73f57ef9 1473 Pfam PF01381 Helix-turn-helix 440 482 1.7E-7 T 30-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CL1_1313 29a6d86887325698b8408f3f73f57ef9 1473 Gene3D G3DSA:1.20.272.10 1381 1473 1.2E-36 T 30-10-2018 CL1_1313 29a6d86887325698b8408f3f73f57ef9 1473 SUPERFAMILY SSF47413 440 483 7.82E-7 T 30-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 CL1_1313 29a6d86887325698b8408f3f73f57ef9 1473 SUPERFAMILY SSF52540 1294 1364 1.33E-13 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_1313 29a6d86887325698b8408f3f73f57ef9 1473 SUPERFAMILY SSF51294 687 1293 2.35E-28 T 30-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CL1_1313 29a6d86887325698b8408f3f73f57ef9 1473 PRINTS PR00379 Intein signature 1083 1095 1.2E-14 T 30-10-2018 IPR006142 Intein GO:0016539 CL1_1313 29a6d86887325698b8408f3f73f57ef9 1473 PRINTS PR00379 Intein signature 975 987 1.2E-14 T 30-10-2018 IPR006142 Intein GO:0016539 CL1_1313 29a6d86887325698b8408f3f73f57ef9 1473 PRINTS PR00379 Intein signature 751 764 1.2E-14 T 30-10-2018 IPR006142 Intein GO:0016539 CL1_1313 29a6d86887325698b8408f3f73f57ef9 1473 PRINTS PR00379 Intein signature 1270 1287 1.2E-14 T 30-10-2018 IPR006142 Intein GO:0016539 CL1_1313 29a6d86887325698b8408f3f73f57ef9 1473 PRINTS PR00379 Intein signature 1288 1297 1.2E-14 T 30-10-2018 IPR006142 Intein GO:0016539 CL1_1313 29a6d86887325698b8408f3f73f57ef9 1473 Pfam PF14890 Intein splicing domain 67 599 1.2E-26 T 30-10-2018 CL1_1313 29a6d86887325698b8408f3f73f57ef9 1473 Gene3D G3DSA:1.10.260.40 439 489 1.9E-6 T 30-10-2018 CL1_1313 29a6d86887325698b8408f3f73f57ef9 1473 Gene3D G3DSA:1.10.8.60 1317 1380 7.3E-27 T 30-10-2018 CL1_1313 29a6d86887325698b8408f3f73f57ef9 1473 SMART SM00530 435 483 6.2E-7 T 30-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CL1_1313 29a6d86887325698b8408f3f73f57ef9 1473 Pfam PF14890 Intein splicing domain 698 1293 7.1E-16 T 30-10-2018 CL1_1313 29a6d86887325698b8408f3f73f57ef9 1473 SMART SM00305 1254 1299 6.5E-8 T 30-10-2018 IPR003586 Hint domain C-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CL1_1313 29a6d86887325698b8408f3f73f57ef9 1473 SMART SM00305 557 605 6.6E-11 T 30-10-2018 IPR003586 Hint domain C-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CL1_1313 29a6d86887325698b8408f3f73f57ef9 1473 Gene3D G3DSA:3.40.50.300 13 67 1.7E-15 T 30-10-2018 CL1_1313 29a6d86887325698b8408f3f73f57ef9 1473 SUPERFAMILY SSF52540 12 60 3.29E-12 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_1313 29a6d86887325698b8408f3f73f57ef9 1473 SUPERFAMILY SSF48019 1382 1471 2.14E-23 T 30-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 CL1_1313 29a6d86887325698b8408f3f73f57ef9 1473 Gene3D G3DSA:2.170.16.10 68 179 9.2E-20 T 30-10-2018 CL1_1313 29a6d86887325698b8408f3f73f57ef9 1473 Gene3D G3DSA:2.170.16.10 541 597 2.9E-13 T 30-10-2018 CL1_1313 29a6d86887325698b8408f3f73f57ef9 1473 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 600 689 1.3E-5 T 30-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CL1_1313 29a6d86887325698b8408f3f73f57ef9 1473 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 15 129 1.1E-6 T 30-10-2018 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 CL1_1313 29a6d86887325698b8408f3f73f57ef9 1473 Gene3D G3DSA:3.40.50.300 598 690 9.6E-24 T 30-10-2018 CL1_1313 29a6d86887325698b8408f3f73f57ef9 1473 SUPERFAMILY SSF55608 1067 1174 1.25E-10 T 30-10-2018 IPR027434 Homing endonuclease CL1_1313 29a6d86887325698b8408f3f73f57ef9 1473 SMART SM00306 685 784 1.0E-14 T 30-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CL1_1313 29a6d86887325698b8408f3f73f57ef9 1473 SMART SM00306 58 169 5.4E-26 T 30-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CL1_1313 29a6d86887325698b8408f3f73f57ef9 1473 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 577 600 6.1E-6 T 30-10-2018 IPR030934 Intein C-terminal splicing region CL1_1313 29a6d86887325698b8408f3f73f57ef9 1473 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 1272 1294 6.6E-7 T 30-10-2018 IPR030934 Intein C-terminal splicing region CL1_1313 29a6d86887325698b8408f3f73f57ef9 1473 Gene3D G3DSA:2.170.16.10 1213 1300 1.6E-7 T 30-10-2018 CL1_1313 29a6d86887325698b8408f3f73f57ef9 1473 SUPERFAMILY SSF52540 600 687 5.86E-19 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_1313 29a6d86887325698b8408f3f73f57ef9 1473 TIGRFAM TIGR01445 intein_Nterm: intein N-terminal splicing region 687 764 7.6E-11 T 30-10-2018 IPR006141 Intein N-terminal splicing region GO:0016539 Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CL1_1313 29a6d86887325698b8408f3f73f57ef9 1473 TIGRFAM TIGR01445 intein_Nterm: intein N-terminal splicing region 60 144 2.4E-16 T 30-10-2018 IPR006141 Intein N-terminal splicing region GO:0016539 Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CL1_1313 29a6d86887325698b8408f3f73f57ef9 1473 SUPERFAMILY SSF51294 59 599 8.37E-43 T 30-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CL1_1313 29a6d86887325698b8408f3f73f57ef9 1473 SUPERFAMILY SSF46785 849 928 3.21E-8 T 30-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CL1_1313 29a6d86887325698b8408f3f73f57ef9 1473 Pfam PF14528 LAGLIDADG-like domain 273 346 4.5E-14 T 30-10-2018 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 CL1_1313 29a6d86887325698b8408f3f73f57ef9 1473 Pfam PF14528 LAGLIDADG-like domain 1082 1170 6.1E-7 T 30-10-2018 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 CL1_1313 29a6d86887325698b8408f3f73f57ef9 1473 Pfam PF14528 LAGLIDADG-like domain 185 247 4.3E-5 T 30-10-2018 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 CL1_1899 b01cf083528e369ed71b1caba6c97d30 223 Gene3D G3DSA:3.40.50.300 1 218 8.1E-73 T 30-10-2018 CL1_1899 b01cf083528e369ed71b1caba6c97d30 223 SUPERFAMILY SSF52540 1 212 5.77E-38 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_1899 b01cf083528e369ed71b1caba6c97d30 223 PRINTS PR00094 Adenylate kinase signature 79 95 2.3E-28 T 30-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CL1_1899 b01cf083528e369ed71b1caba6c97d30 223 PRINTS PR00094 Adenylate kinase signature 32 46 2.3E-28 T 30-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CL1_1899 b01cf083528e369ed71b1caba6c97d30 223 PRINTS PR00094 Adenylate kinase signature 4 17 2.3E-28 T 30-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CL1_1899 b01cf083528e369ed71b1caba6c97d30 223 PRINTS PR00094 Adenylate kinase signature 158 173 2.3E-28 T 30-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CL1_1899 b01cf083528e369ed71b1caba6c97d30 223 PRINTS PR00094 Adenylate kinase signature 175 189 2.3E-28 T 30-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CL1_1899 b01cf083528e369ed71b1caba6c97d30 223 TIGRFAM TIGR01351 adk: adenylate kinase 2 209 6.6E-70 T 30-10-2018 IPR006259 Adenylate kinase subfamily GO:0004017|GO:0005524|GO:0016776 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 CL1_1899 b01cf083528e369ed71b1caba6c97d30 223 Hamap MF_00235 Adenylate kinase [adk]. 1 211 44.346 T 30-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CL1_1899 b01cf083528e369ed71b1caba6c97d30 223 Pfam PF05191 Adenylate kinase, active site lid 125 160 5.3E-17 T 30-10-2018 IPR007862 Adenylate kinase, active site lid domain GO:0004017 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 CL1_1899 b01cf083528e369ed71b1caba6c97d30 223 ProSitePatterns PS00113 Adenylate kinase signature. 79 90 - T 30-10-2018 IPR033690 Adenylate kinase, conserved site KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CL1_1899 b01cf083528e369ed71b1caba6c97d30 223 Pfam PF00406 Adenylate kinase 5 188 1.7E-39 T 30-10-2018 CL1_1944 e234a47fc06f1053cceb4595b80d3d31 269 Gene3D G3DSA:3.60.20.10 7 252 6.9E-14 T 30-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CL1_1944 e234a47fc06f1053cceb4595b80d3d31 269 Pfam PF13522 Glutamine amidotransferase domain 79 169 9.3E-7 T 30-10-2018 CL1_1944 e234a47fc06f1053cceb4595b80d3d31 269 SUPERFAMILY SSF56235 8 260 2.98E-18 T 30-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CL1_0612 69ead528f7d72ab1d8d1d9c1f43ece3a 130 Gene3D G3DSA:3.30.1490.10 70 128 1.5E-27 T 30-10-2018 CL1_0612 69ead528f7d72ab1d8d1d9c1f43ece3a 130 Gene3D G3DSA:3.30.1370.30 1 69 7.0E-32 T 30-10-2018 CL1_0612 69ead528f7d72ab1d8d1d9c1f43ece3a 130 ProSitePatterns PS00053 Ribosomal protein S8 signature. 100 117 - T 30-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0612 69ead528f7d72ab1d8d1d9c1f43ece3a 130 Pfam PF00410 Ribosomal protein S8 5 130 1.3E-27 T 30-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0612 69ead528f7d72ab1d8d1d9c1f43ece3a 130 Hamap MF_01302_A 30S ribosomal protein S8 [rpsH]. 2 130 38.288 T 30-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0612 69ead528f7d72ab1d8d1d9c1f43ece3a 130 SUPERFAMILY SSF56047 3 130 1.22E-39 T 30-10-2018 IPR035987 Ribosomal protein S8 superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_1643 e97c4d12941f7c19d3919907e830c9d7 334 SMART SM00797 23 300 6.4E-133 T 30-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B CL1_1643 e97c4d12941f7c19d3919907e830c9d7 334 SUPERFAMILY SSF50891 174 288 1.25E-11 T 30-10-2018 IPR029000 Cyclophilin-like domain superfamily CL1_1643 e97c4d12941f7c19d3919907e830c9d7 334 TIGRFAM TIGR00724 urea_amlyse_rel: biotin-dependent carboxylase uncharacterized domain 1 309 4.3E-102 T 30-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B CL1_1643 e97c4d12941f7c19d3919907e830c9d7 334 Pfam PF02626 Carboxyltransferase domain, subdomain A and B 24 283 1.5E-82 T 30-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B CL1_1643 e97c4d12941f7c19d3919907e830c9d7 334 Gene3D G3DSA:2.40.100.10 172 311 4.1E-46 T 30-10-2018 IPR029000 Cyclophilin-like domain superfamily CL1_1051 19835f4ef3e7b11a3e399e821cb822da 223 Hamap MF_00722 Endonuclease NucS [nucS]. 1 214 38.813 T 30-10-2018 IPR002793 Endonuclease NucS GO:0004519 CL1_1051 19835f4ef3e7b11a3e399e821cb822da 223 Gene3D G3DSA:3.40.1350.10 98 209 1.3E-42 T 30-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 CL1_1051 19835f4ef3e7b11a3e399e821cb822da 223 Gene3D G3DSA:2.70.180.20 1 97 7.2E-36 T 30-10-2018 CL1_1051 19835f4ef3e7b11a3e399e821cb822da 223 Pfam PF01939 Endonuclease NucS 1 220 2.9E-91 T 30-10-2018 IPR002793 Endonuclease NucS GO:0004519 CL1_0183 04c6e6a3a86b6c7f7e4c3c8dfe1844d1 428 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 209 295 1.8E-24 T 30-10-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CL1_0183 04c6e6a3a86b6c7f7e4c3c8dfe1844d1 428 SUPERFAMILY SSF48179 209 299 4.59E-27 T 30-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 CL1_0183 04c6e6a3a86b6c7f7e4c3c8dfe1844d1 428 Gene3D G3DSA:3.40.50.720 11 206 2.3E-71 T 30-10-2018 CL1_0183 04c6e6a3a86b6c7f7e4c3c8dfe1844d1 428 PIRSF PIRSF000124 10 416 4.4E-81 T 30-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 CL1_0183 04c6e6a3a86b6c7f7e4c3c8dfe1844d1 428 SUPERFAMILY SSF51735 12 200 1.43E-49 T 30-10-2018 IPR036291 NAD(P)-binding domain superfamily CL1_0183 04c6e6a3a86b6c7f7e4c3c8dfe1844d1 428 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 11 191 1.3E-50 T 30-10-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CL1_0183 04c6e6a3a86b6c7f7e4c3c8dfe1844d1 428 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 11 408 2.4E-124 T 30-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 CL1_0183 04c6e6a3a86b6c7f7e4c3c8dfe1844d1 428 SMART SM00984 322 413 1.7E-34 T 30-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CL1_0183 04c6e6a3a86b6c7f7e4c3c8dfe1844d1 428 SUPERFAMILY SSF52413 311 412 1.14E-24 T 30-10-2018 IPR036220 UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily Reactome: R-HSA-173599 CL1_0183 04c6e6a3a86b6c7f7e4c3c8dfe1844d1 428 PIRSF PIRSF500136 1 425 2.1E-143 T 30-10-2018 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 CL1_0183 04c6e6a3a86b6c7f7e4c3c8dfe1844d1 428 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 322 412 8.0E-24 T 30-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CL1_0183 04c6e6a3a86b6c7f7e4c3c8dfe1844d1 428 Gene3D G3DSA:3.40.50.720 240 428 4.3E-67 T 30-10-2018 CL1_0270 776d41b49a9d34b9b0f18b8df7661f05 322 Pfam PF00586 AIR synthase related protein, N-terminal domain 24 133 7.3E-18 T 30-10-2018 IPR016188 PurM-like, N-terminal domain CL1_0270 776d41b49a9d34b9b0f18b8df7661f05 322 Gene3D G3DSA:3.30.1330.10 1 138 6.6E-35 T 30-10-2018 IPR036921 PurM-like, N-terminal domain superfamily CL1_0270 776d41b49a9d34b9b0f18b8df7661f05 322 Hamap MF_02128 Thiamine-monophosphate kinase [thiL]. 1 309 29.045 T 30-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 CL1_0270 776d41b49a9d34b9b0f18b8df7661f05 322 TIGRFAM TIGR01379 thiL: thiamine-phosphate kinase 3 309 6.7E-86 T 30-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 CL1_0270 776d41b49a9d34b9b0f18b8df7661f05 322 SUPERFAMILY SSF56042 137 296 1.35E-39 T 30-10-2018 IPR036676 PurM-like, C-terminal domain superfamily CL1_0270 776d41b49a9d34b9b0f18b8df7661f05 322 Gene3D G3DSA:3.90.650.10 139 309 4.4E-47 T 30-10-2018 IPR036676 PurM-like, C-terminal domain superfamily CL1_0270 776d41b49a9d34b9b0f18b8df7661f05 322 SUPERFAMILY SSF55326 9 133 1.64E-31 T 30-10-2018 IPR036921 PurM-like, N-terminal domain superfamily CL1_0270 776d41b49a9d34b9b0f18b8df7661f05 322 Pfam PF02769 AIR synthase related protein, C-terminal domain 144 292 2.6E-9 T 30-10-2018 IPR010918 PurM-like, C-terminal domain CL1_0270 776d41b49a9d34b9b0f18b8df7661f05 322 PIRSF PIRSF005303 1 309 1.5E-90 T 30-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 CL1_1001 b03b197034e50146975ede5fd892188d 65 TIGRFAM TIGR04140 chp_AF_0576: TIGR04140 family protein 2 65 2.8E-23 T 30-10-2018 IPR026486 Uncharacterised protein AF_0576 CL1_0434 f346e60037e68ccb75120f0490577eeb 223 SUPERFAMILY SSF56784 1 185 1.15E-18 T 30-10-2018 IPR036412 HAD-like superfamily CL1_0434 f346e60037e68ccb75120f0490577eeb 223 Gene3D G3DSA:3.40.50.1000 5 163 2.0E-11 T 30-10-2018 IPR023214 HAD superfamily CL1_0434 f346e60037e68ccb75120f0490577eeb 223 Gene3D G3DSA:1.10.150.240 13 85 2.0E-11 T 30-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 CL1_0434 f346e60037e68ccb75120f0490577eeb 223 Pfam PF13419 Haloacid dehalogenase-like hydrolase 3 135 1.8E-11 T 30-10-2018 CL1_0336 54c1a541f815a6b403c2514db6309c18 421 Gene3D G3DSA:3.40.1670.10 296 408 1.1E-37 T 30-10-2018 CL1_0336 54c1a541f815a6b403c2514db6309c18 421 SUPERFAMILY SSF143968 282 419 1.83E-41 T 30-10-2018 CL1_0336 54c1a541f815a6b403c2514db6309c18 421 Pfam PF01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 10 385 3.8E-102 T 30-10-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 CL1_0336 54c1a541f815a6b403c2514db6309c18 421 SUPERFAMILY SSF50475 7 279 4.71E-66 T 30-10-2018 CL1_0336 54c1a541f815a6b403c2514db6309c18 421 TIGRFAM TIGR00148 TIGR00148: decarboxylase, UbiD family 6 409 2.6E-114 T 30-10-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 CL1_0313 1c65e96d2b8aca6a15cdf7b34914dd3d 128 Gene3D G3DSA:1.10.1520.20 2 127 1.4E-46 T 30-10-2018 IPR038133 Ribonuclease III superfamily, archaeal CL1_0313 1c65e96d2b8aca6a15cdf7b34914dd3d 128 SUPERFAMILY SSF69065 7 127 1.24E-51 T 30-10-2018 IPR036389 Ribonuclease III, endonuclease domain superfamily GO:0004525|GO:0006396 CL1_0313 1c65e96d2b8aca6a15cdf7b34914dd3d 128 Pfam PF11469 Ribonuclease III 11 127 5.2E-59 T 30-10-2018 IPR021568 Ribonuclease III, archaeal CL1_0508 23a0e279e9b2de300ae0a3a6107d2599 784 TIGRFAM TIGR01418 PEP_synth: phosphoenolpyruvate synthase 7 771 1.4E-290 T 30-10-2018 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484|MetaCyc: PWY-6142 CL1_0508 23a0e279e9b2de300ae0a3a6107d2599 784 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 473 770 6.3E-97 T 30-10-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 CL1_0508 23a0e279e9b2de300ae0a3a6107d2599 784 SUPERFAMILY SSF51621 485 778 1.49E-94 T 30-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 CL1_0508 23a0e279e9b2de300ae0a3a6107d2599 784 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 729 741 6.5E-14 T 30-10-2018 CL1_0508 23a0e279e9b2de300ae0a3a6107d2599 784 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 512 531 6.5E-14 T 30-10-2018 CL1_0508 23a0e279e9b2de300ae0a3a6107d2599 784 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 676 691 6.5E-14 T 30-10-2018 CL1_0508 23a0e279e9b2de300ae0a3a6107d2599 784 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 693 708 6.5E-14 T 30-10-2018 CL1_0508 23a0e279e9b2de300ae0a3a6107d2599 784 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 676 694 - T 30-10-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 CL1_0508 23a0e279e9b2de300ae0a3a6107d2599 784 Pfam PF00391 PEP-utilising enzyme, mobile domain 382 454 8.0E-29 T 30-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CL1_0508 23a0e279e9b2de300ae0a3a6107d2599 784 SUPERFAMILY SSF52009 354 462 5.62E-37 T 30-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 CL1_0508 23a0e279e9b2de300ae0a3a6107d2599 784 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 413 424 - T 30-10-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 CL1_0508 23a0e279e9b2de300ae0a3a6107d2599 784 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 19 348 2.5E-119 T 30-10-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 CL1_0508 23a0e279e9b2de300ae0a3a6107d2599 784 Gene3D G3DSA:3.30.470.20 198 354 8.1E-54 T 30-10-2018 CL1_0508 23a0e279e9b2de300ae0a3a6107d2599 784 Gene3D G3DSA:3.50.30.10 355 462 3.7E-43 T 30-10-2018 CL1_0508 23a0e279e9b2de300ae0a3a6107d2599 784 Gene3D G3DSA:3.20.20.60 463 783 2.0E-103 T 30-10-2018 CL1_0508 23a0e279e9b2de300ae0a3a6107d2599 784 Gene3D G3DSA:3.30.1490.20 3 197 1.3E-72 T 30-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 CL1_0508 23a0e279e9b2de300ae0a3a6107d2599 784 SUPERFAMILY SSF56059 4 382 1.29E-107 T 30-10-2018 CL1_0508 23a0e279e9b2de300ae0a3a6107d2599 784 PIRSF PIRSF000854 1 775 1.0E-207 T 30-10-2018 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484|MetaCyc: PWY-6142 CL1_0178 7066d3dc926dbadb72ecfc4d5daf32cf 417 Gene3D G3DSA:3.30.960.10 2 137 1.7E-54 T 30-10-2018 IPR024049 Peptide Chain Release Factor eRF1/aRF1, N-terminal Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0178 7066d3dc926dbadb72ecfc4d5daf32cf 417 Pfam PF03464 eRF1 domain 2 142 274 2.0E-49 T 30-10-2018 IPR005141 eRF1 domain 2 CL1_0178 7066d3dc926dbadb72ecfc4d5daf32cf 417 SUPERFAMILY SSF55315 274 416 5.77E-39 T 30-10-2018 IPR029064 50S ribosomal protein L30e-like CL1_0178 7066d3dc926dbadb72ecfc4d5daf32cf 417 SUPERFAMILY SSF55481 3 137 6.02E-49 T 30-10-2018 IPR024049 Peptide Chain Release Factor eRF1/aRF1, N-terminal Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0178 7066d3dc926dbadb72ecfc4d5daf32cf 417 SUPERFAMILY SSF53137 140 273 1.66E-43 T 30-10-2018 CL1_0178 7066d3dc926dbadb72ecfc4d5daf32cf 417 SMART SM01194 3 137 1.1E-34 T 30-10-2018 IPR005140 eRF1 domain 1/Pelota-like CL1_0178 7066d3dc926dbadb72ecfc4d5daf32cf 417 Pfam PF03465 eRF1 domain 3 278 416 1.1E-33 T 30-10-2018 IPR005142 eRF1 domain 3 CL1_0178 7066d3dc926dbadb72ecfc4d5daf32cf 417 Gene3D G3DSA:3.30.420.60 139 273 1.2E-53 T 30-10-2018 CL1_0178 7066d3dc926dbadb72ecfc4d5daf32cf 417 TIGRFAM TIGR03676 aRF1/eRF1: peptide chain release factor 1, archaeal and eukaryotic forms 9 416 1.2E-181 T 30-10-2018 IPR004403 Peptide chain release factor eRF1/aRF1 GO:0003747|GO:0005737|GO:0006415 Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0178 7066d3dc926dbadb72ecfc4d5daf32cf 417 Hamap MF_00424 Peptide chain release factor subunit 1 [prf1]. 20 417 45.317 T 30-10-2018 IPR020918 Peptide chain release factor aRF1 GO:0003747|GO:0005737|GO:0006415 CL1_0178 7066d3dc926dbadb72ecfc4d5daf32cf 417 Gene3D G3DSA:3.30.1330.30 276 417 3.0E-42 T 30-10-2018 IPR029064 50S ribosomal protein L30e-like CL1_0178 7066d3dc926dbadb72ecfc4d5daf32cf 417 Pfam PF03463 eRF1 domain 1 22 135 6.3E-9 T 30-10-2018 IPR005140 eRF1 domain 1/Pelota-like CL1_0698 d84c6f25d4cc4982ac5a7fdaa7a4d9c1 1471 SUPERFAMILY SSF51294 1078 1236 1.57E-29 T 30-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CL1_0698 d84c6f25d4cc4982ac5a7fdaa7a4d9c1 1471 Gene3D G3DSA:3.30.420.10 131 347 5.9E-171 T 30-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 CL1_0698 d84c6f25d4cc4982ac5a7fdaa7a4d9c1 1471 Gene3D G3DSA:3.30.342.10 3 366 5.9E-171 T 30-10-2018 CL1_0698 d84c6f25d4cc4982ac5a7fdaa7a4d9c1 1471 Gene3D G3DSA:3.90.1600.20 378 444 3.5E-13 T 30-10-2018 CL1_0698 d84c6f25d4cc4982ac5a7fdaa7a4d9c1 1471 Gene3D G3DSA:3.90.1600.10 1231 1301 8.0E-16 T 30-10-2018 IPR023211 DNA polymerase, palm domain superfamily KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CL1_0698 d84c6f25d4cc4982ac5a7fdaa7a4d9c1 1471 Gene3D G3DSA:3.90.1600.10 1027 1081 3.7E-13 T 30-10-2018 IPR023211 DNA polymerase, palm domain superfamily KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CL1_0698 d84c6f25d4cc4982ac5a7fdaa7a4d9c1 1471 Gene3D G3DSA:1.10.287.690 447 493 1.1E-17 T 30-10-2018 CL1_0698 d84c6f25d4cc4982ac5a7fdaa7a4d9c1 1471 Gene3D G3DSA:1.10.132.60 1302 1468 3.1E-62 T 30-10-2018 CL1_0698 d84c6f25d4cc4982ac5a7fdaa7a4d9c1 1471 SUPERFAMILY SSF56672 349 493 1.89E-43 T 30-10-2018 CL1_0698 d84c6f25d4cc4982ac5a7fdaa7a4d9c1 1471 Pfam PF03104 DNA polymerase family B, exonuclease domain 130 278 2.9E-34 T 30-10-2018 IPR006133 DNA-directed DNA polymerase, family B, exonuclease domain KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CL1_0698 d84c6f25d4cc4982ac5a7fdaa7a4d9c1 1471 Pfam PF03104 DNA polymerase family B, exonuclease domain 21 129 1.4E-14 T 30-10-2018 IPR006133 DNA-directed DNA polymerase, family B, exonuclease domain KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CL1_0698 d84c6f25d4cc4982ac5a7fdaa7a4d9c1 1471 TIGRFAM TIGR01445 intein_Nterm: intein N-terminal splicing region 505 590 4.3E-9 T 30-10-2018 IPR006141 Intein N-terminal splicing region GO:0016539 Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CL1_0698 d84c6f25d4cc4982ac5a7fdaa7a4d9c1 1471 TIGRFAM TIGR01445 intein_Nterm: intein N-terminal splicing region 1079 1169 2.7E-12 T 30-10-2018 IPR006141 Intein N-terminal splicing region GO:0016539 Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CL1_0698 d84c6f25d4cc4982ac5a7fdaa7a4d9c1 1471 Pfam PF14890 Intein splicing domain 510 1028 3.8E-50 T 30-10-2018 CL1_0698 d84c6f25d4cc4982ac5a7fdaa7a4d9c1 1471 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 1214 1236 6.2E-9 T 30-10-2018 IPR030934 Intein C-terminal splicing region CL1_0698 d84c6f25d4cc4982ac5a7fdaa7a4d9c1 1471 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 1005 1029 1.1E-6 T 30-10-2018 IPR030934 Intein C-terminal splicing region CL1_0698 d84c6f25d4cc4982ac5a7fdaa7a4d9c1 1471 SMART SM00486 133 540 2.7E-104 T 30-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CL1_0698 d84c6f25d4cc4982ac5a7fdaa7a4d9c1 1471 SMART SM00305 986 1034 1.4E-12 T 30-10-2018 IPR003586 Hint domain C-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CL1_0698 d84c6f25d4cc4982ac5a7fdaa7a4d9c1 1471 SMART SM00305 1195 1241 3.0E-11 T 30-10-2018 IPR003586 Hint domain C-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CL1_0698 d84c6f25d4cc4982ac5a7fdaa7a4d9c1 1471 Pfam PF14528 LAGLIDADG-like domain 865 923 4.4E-6 T 30-10-2018 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 CL1_0698 d84c6f25d4cc4982ac5a7fdaa7a4d9c1 1471 TIGRFAM TIGR00592 pol2: DNA polymerase (pol2) 3 492 1.3E-101 T 30-10-2018 CL1_0698 d84c6f25d4cc4982ac5a7fdaa7a4d9c1 1471 Gene3D G3DSA:2.170.16.10 1082 1230 3.8E-31 T 30-10-2018 CL1_0698 d84c6f25d4cc4982ac5a7fdaa7a4d9c1 1471 SUPERFAMILY SSF55608 848 941 2.72E-18 T 30-10-2018 IPR027434 Homing endonuclease CL1_0698 d84c6f25d4cc4982ac5a7fdaa7a4d9c1 1471 SUPERFAMILY SSF56672 1027 1454 1.65E-76 T 30-10-2018 CL1_0698 d84c6f25d4cc4982ac5a7fdaa7a4d9c1 1471 SUPERFAMILY SSF51294 492 1029 3.14E-39 T 30-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CL1_0698 d84c6f25d4cc4982ac5a7fdaa7a4d9c1 1471 Gene3D G3DSA:3.30.1490.210 934 986 1.9E-219 T 30-10-2018 CL1_0698 d84c6f25d4cc4982ac5a7fdaa7a4d9c1 1471 SMART SM00306 1076 1193 4.9E-19 T 30-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CL1_0698 d84c6f25d4cc4982ac5a7fdaa7a4d9c1 1471 SMART SM00306 490 615 6.4E-28 T 30-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CL1_0698 d84c6f25d4cc4982ac5a7fdaa7a4d9c1 1471 SUPERFAMILY SSF53098 1 347 7.59E-89 T 30-10-2018 IPR012337 Ribonuclease H-like superfamily CL1_0698 d84c6f25d4cc4982ac5a7fdaa7a4d9c1 1471 Pfam PF00136 DNA polymerase family B 1028 1069 1.1E-6 T 30-10-2018 IPR006134 DNA-directed DNA polymerase, family B, multifunctional domain GO:0000166|GO:0003677 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CL1_0698 d84c6f25d4cc4982ac5a7fdaa7a4d9c1 1471 Pfam PF00136 DNA polymerase family B 1236 1441 1.3E-29 T 30-10-2018 IPR006134 DNA-directed DNA polymerase, family B, multifunctional domain GO:0000166|GO:0003677 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CL1_0698 d84c6f25d4cc4982ac5a7fdaa7a4d9c1 1471 Pfam PF00136 DNA polymerase family B 352 493 3.0E-29 T 30-10-2018 IPR006134 DNA-directed DNA polymerase, family B, multifunctional domain GO:0000166|GO:0003677 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CL1_0698 d84c6f25d4cc4982ac5a7fdaa7a4d9c1 1471 Gene3D G3DSA:1.10.10.1010 619 764 1.9E-219 T 30-10-2018 CL1_0698 d84c6f25d4cc4982ac5a7fdaa7a4d9c1 1471 PRINTS PR00379 Intein signature 865 877 1.1E-25 T 30-10-2018 IPR006142 Intein GO:0016539 CL1_0698 d84c6f25d4cc4982ac5a7fdaa7a4d9c1 1471 PRINTS PR00379 Intein signature 1003 1020 1.1E-25 T 30-10-2018 IPR006142 Intein GO:0016539 CL1_0698 d84c6f25d4cc4982ac5a7fdaa7a4d9c1 1471 PRINTS PR00379 Intein signature 892 907 1.1E-25 T 30-10-2018 IPR006142 Intein GO:0016539 CL1_0698 d84c6f25d4cc4982ac5a7fdaa7a4d9c1 1471 PRINTS PR00379 Intein signature 1230 1239 1.1E-25 T 30-10-2018 IPR006142 Intein GO:0016539 CL1_0698 d84c6f25d4cc4982ac5a7fdaa7a4d9c1 1471 PRINTS PR00379 Intein signature 578 591 1.1E-25 T 30-10-2018 IPR006142 Intein GO:0016539 CL1_0698 d84c6f25d4cc4982ac5a7fdaa7a4d9c1 1471 PRINTS PR00379 Intein signature 769 781 1.1E-25 T 30-10-2018 IPR006142 Intein GO:0016539 CL1_0698 d84c6f25d4cc4982ac5a7fdaa7a4d9c1 1471 Gene3D G3DSA:2.170.16.10 505 1026 1.9E-219 T 30-10-2018 CL1_0698 d84c6f25d4cc4982ac5a7fdaa7a4d9c1 1471 Gene3D G3DSA:3.10.28.10 765 933 1.9E-219 T 30-10-2018 IPR027434 Homing endonuclease CL1_0286 f9a592e5f6c29bc8594d7c7f5f9885b9 439 Pfam PF00710 Asparaginase, N-terminal 94 287 6.1E-63 T 30-10-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 CL1_0286 f9a592e5f6c29bc8594d7c7f5f9885b9 439 ProSitePatterns PS00144 Asparaginase / glutaminase active site signature 1. 97 105 - T 30-10-2018 IPR020827 Asparaginase/glutaminase, active site 1 GO:0006520 CL1_0286 f9a592e5f6c29bc8594d7c7f5f9885b9 439 SMART SM00870 94 417 3.4E-156 T 30-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CL1_0286 f9a592e5f6c29bc8594d7c7f5f9885b9 439 TIGRFAM TIGR02153 gatD_arch: glutamyl-tRNA(Gln) amidotransferase, subunit D 31 433 3.9E-199 T 30-10-2018 IPR011878 Glutamyl-tRNA(Gln) amidotransferase subunit D GO:0006450 CL1_0286 f9a592e5f6c29bc8594d7c7f5f9885b9 439 PIRSF PIRSF001220 90 428 3.9E-112 T 30-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CL1_0286 f9a592e5f6c29bc8594d7c7f5f9885b9 439 Gene3D G3DSA:3.40.50.40 302 439 1.2E-57 T 30-10-2018 IPR027473 L-asparaginase, C-terminal Reactome: R-HSA-70614 CL1_0286 f9a592e5f6c29bc8594d7c7f5f9885b9 439 SUPERFAMILY SSF141300 4 76 1.96E-19 T 30-10-2018 IPR037222 GatD, N-terminal CL1_0286 f9a592e5f6c29bc8594d7c7f5f9885b9 439 Gene3D G3DSA:2.30.30.520 2 77 8.7E-22 T 30-10-2018 IPR037222 GatD, N-terminal CL1_0286 f9a592e5f6c29bc8594d7c7f5f9885b9 439 PRINTS PR00139 Asparaginase/glutaminase family signature 354 372 1.9E-19 T 30-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CL1_0286 f9a592e5f6c29bc8594d7c7f5f9885b9 439 PRINTS PR00139 Asparaginase/glutaminase family signature 95 106 1.9E-19 T 30-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CL1_0286 f9a592e5f6c29bc8594d7c7f5f9885b9 439 PRINTS PR00139 Asparaginase/glutaminase family signature 171 189 1.9E-19 T 30-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 CL1_0286 f9a592e5f6c29bc8594d7c7f5f9885b9 439 SUPERFAMILY SSF53774 87 436 8.11E-122 T 30-10-2018 IPR036152 Asparaginase/glutaminase-like superfamily Reactome: R-HSA-70614 CL1_0286 f9a592e5f6c29bc8594d7c7f5f9885b9 439 Hamap MF_00586 Glutamyl-tRNA(Gln) amidotransferase subunit D [gatD]. 19 433 49.316 T 30-10-2018 IPR011878 Glutamyl-tRNA(Gln) amidotransferase subunit D GO:0006450 CL1_0286 f9a592e5f6c29bc8594d7c7f5f9885b9 439 Gene3D G3DSA:3.40.50.1170 80 301 1.0E-87 T 30-10-2018 IPR037152 L-asparaginase, N-terminal domain superfamily Reactome: R-HSA-70614 CL1_0286 f9a592e5f6c29bc8594d7c7f5f9885b9 439 PIRSF PIRSF500175 13 437 2.4E-192 T 30-10-2018 IPR011878 Glutamyl-tRNA(Gln) amidotransferase subunit D GO:0006450 CL1_0286 f9a592e5f6c29bc8594d7c7f5f9885b9 439 TIGRFAM TIGR00519 asnASE_I: L-asparaginase, type I 92 429 2.4E-151 T 30-10-2018 IPR006033 L-asparaginase, type I GO:0004067|GO:0006520 Reactome: R-HSA-70614 CL1_0286 f9a592e5f6c29bc8594d7c7f5f9885b9 439 ProSitePatterns PS00917 Asparaginase / glutaminase active site signature 2. 172 182 - T 30-10-2018 IPR027475 Asparaginase/glutaminase, active site 2 Reactome: R-HSA-70614 CL1_1597 535f225144df47bf6bd013b6364bdd99 387 Gene3D G3DSA:1.25.40.10 167 384 2.8E-9 T 30-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 CL1_1597 535f225144df47bf6bd013b6364bdd99 387 SUPERFAMILY SSF48452 118 258 1.09E-7 T 30-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 CL1_0891 297d7f376f864f4dd20ecbe9d22ad7f1 454 Gene3D G3DSA:3.40.120.10 246 349 1.2E-47 T 30-10-2018 CL1_0891 297d7f376f864f4dd20ecbe9d22ad7f1 454 Gene3D G3DSA:3.40.120.10 163 344 1.2E-47 T 30-10-2018 CL1_0891 297d7f376f864f4dd20ecbe9d22ad7f1 454 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 149 245 1.7E-25 T 30-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CL1_0891 297d7f376f864f4dd20ecbe9d22ad7f1 454 SUPERFAMILY SSF55957 355 448 1.83E-20 T 30-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CL1_0891 297d7f376f864f4dd20ecbe9d22ad7f1 454 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 88 97 - T 30-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CL1_0891 297d7f376f864f4dd20ecbe9d22ad7f1 454 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 250 356 1.5E-7 T 30-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CL1_0891 297d7f376f864f4dd20ecbe9d22ad7f1 454 SUPERFAMILY SSF53738 147 247 2.55E-27 T 30-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CL1_0891 297d7f376f864f4dd20ecbe9d22ad7f1 454 TIGRFAM TIGR03990 Arch_GlmM: phosphoglucosamine mutase 1 439 3.8E-147 T 30-10-2018 IPR024086 Phosphoglucosamine mutase, archaeal type GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CL1_0891 297d7f376f864f4dd20ecbe9d22ad7f1 454 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 2 129 1.4E-39 T 30-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CL1_0891 297d7f376f864f4dd20ecbe9d22ad7f1 454 Gene3D G3DSA:3.40.120.10 1 145 2.1E-46 T 30-10-2018 CL1_0891 297d7f376f864f4dd20ecbe9d22ad7f1 454 SUPERFAMILY SSF53738 2 169 3.02E-41 T 30-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CL1_0891 297d7f376f864f4dd20ecbe9d22ad7f1 454 SUPERFAMILY SSF53738 250 351 1.57E-12 T 30-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CL1_0891 297d7f376f864f4dd20ecbe9d22ad7f1 454 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 380 435 1.9E-11 T 30-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CL1_0891 297d7f376f864f4dd20ecbe9d22ad7f1 454 Gene3D G3DSA:3.30.310.50 360 451 4.5E-17 T 30-10-2018 CL1_0891 297d7f376f864f4dd20ecbe9d22ad7f1 454 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 87 101 1.6E-16 T 30-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CL1_0891 297d7f376f864f4dd20ecbe9d22ad7f1 454 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 163 182 1.6E-16 T 30-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CL1_0891 297d7f376f864f4dd20ecbe9d22ad7f1 454 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 197 210 1.6E-16 T 30-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CL1_0891 297d7f376f864f4dd20ecbe9d22ad7f1 454 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 225 240 1.6E-16 T 30-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CL1_1264 fee1b53ab015a068e52fb59b340155ad 428 SUPERFAMILY SSF51735 158 415 2.71E-64 T 30-10-2018 IPR036291 NAD(P)-binding domain superfamily CL1_1264 fee1b53ab015a068e52fb59b340155ad 428 SMART SM00919 158 388 6.2E-101 T 30-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 CL1_1264 fee1b53ab015a068e52fb59b340155ad 428 Gene3D G3DSA:3.40.50.720 156 428 5.8E-96 T 30-10-2018 CL1_1264 fee1b53ab015a068e52fb59b340155ad 428 Pfam PF03949 Malic enzyme, NAD binding domain 159 203 1.1E-7 T 30-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 CL1_1264 fee1b53ab015a068e52fb59b340155ad 428 Pfam PF03949 Malic enzyme, NAD binding domain 286 387 1.4E-8 T 30-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 CL1_1264 fee1b53ab015a068e52fb59b340155ad 428 SUPERFAMILY SSF53223 11 156 1.87E-51 T 30-10-2018 CL1_1264 fee1b53ab015a068e52fb59b340155ad 428 SMART SM01274 14 146 2.7E-77 T 30-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CL1_1264 fee1b53ab015a068e52fb59b340155ad 428 Pfam PF00390 Malic enzyme, N-terminal domain 16 146 1.6E-26 T 30-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CL1_1264 fee1b53ab015a068e52fb59b340155ad 428 ProSitePatterns PS00331 Malic enzymes signature. 154 170 - T 30-10-2018 IPR015884 Malic enzyme, conserved site GO:0004471|GO:0055114 CL1_1264 fee1b53ab015a068e52fb59b340155ad 428 PIRSF PIRSF000106 22 418 9.5E-78 T 30-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 CL1_1264 fee1b53ab015a068e52fb59b340155ad 428 Gene3D G3DSA:3.40.50.10380 1 155 1.1E-66 T 30-10-2018 IPR037062 Malic enzyme, N-terminal domain superfamily GO:0004471|GO:0055114 CL1_1294 100e9b94b7bbbe2b3628638b337e3076 311 SUPERFAMILY SSF53671 2 306 2.75E-103 T 30-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 CL1_1294 100e9b94b7bbbe2b3628638b337e3076 311 PRINTS PR00101 Aspartate carbamoyltransferase signature 286 300 1.8E-38 T 30-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CL1_1294 100e9b94b7bbbe2b3628638b337e3076 311 PRINTS PR00101 Aspartate carbamoyltransferase signature 264 269 1.8E-38 T 30-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CL1_1294 100e9b94b7bbbe2b3628638b337e3076 311 PRINTS PR00101 Aspartate carbamoyltransferase signature 41 63 1.8E-38 T 30-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CL1_1294 100e9b94b7bbbe2b3628638b337e3076 311 PRINTS PR00101 Aspartate carbamoyltransferase signature 80 89 1.8E-38 T 30-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CL1_1294 100e9b94b7bbbe2b3628638b337e3076 311 PRINTS PR00101 Aspartate carbamoyltransferase signature 134 151 1.8E-38 T 30-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CL1_1294 100e9b94b7bbbe2b3628638b337e3076 311 PRINTS PR00101 Aspartate carbamoyltransferase signature 225 234 1.8E-38 T 30-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CL1_1294 100e9b94b7bbbe2b3628638b337e3076 311 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 6 147 5.7E-50 T 30-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 CL1_1294 100e9b94b7bbbe2b3628638b337e3076 311 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 154 302 1.5E-31 T 30-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 CL1_1294 100e9b94b7bbbe2b3628638b337e3076 311 Gene3D G3DSA:3.40.50.1370 135 292 4.9E-126 T 30-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 CL1_1294 100e9b94b7bbbe2b3628638b337e3076 311 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 135 146 3.7E-24 T 30-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CL1_1294 100e9b94b7bbbe2b3628638b337e3076 311 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 51 70 3.7E-24 T 30-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CL1_1294 100e9b94b7bbbe2b3628638b337e3076 311 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 260 269 3.7E-24 T 30-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CL1_1294 100e9b94b7bbbe2b3628638b337e3076 311 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 270 293 3.7E-24 T 30-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CL1_1294 100e9b94b7bbbe2b3628638b337e3076 311 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 6 304 1.1E-132 T 30-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CL1_1294 100e9b94b7bbbe2b3628638b337e3076 311 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 5 307 39.756 T 30-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CL1_1294 100e9b94b7bbbe2b3628638b337e3076 311 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 51 58 - T 30-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CL1_1294 100e9b94b7bbbe2b3628638b337e3076 311 Gene3D G3DSA:3.40.50.1370 7 301 4.9E-126 T 30-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 CL1_1098 f57fffb60da6ceabb05fd61cd5979885 171 Pfam PF01864 CDP-archaeol synthase 7 171 8.0E-59 T 30-10-2018 IPR032690 CDP-archaeol synthase KEGG: 00564+2.7.7.67|MetaCyc: PWY-6349 CL1_1098 f57fffb60da6ceabb05fd61cd5979885 171 Hamap MF_01117 CDP-archaeol synthase [carS]. 14 171 28.231 T 30-10-2018 IPR002726 CDP-archaeol synthase, archaea KEGG: 00564+2.7.7.67|MetaCyc: PWY-6349 CL1_1439 8786150d7f5c8744b0c57b83ac806f39 480 SUPERFAMILY SSF51971 157 408 7.65E-70 T 30-10-2018 CL1_1439 8786150d7f5c8744b0c57b83ac806f39 480 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 159 457 8.6E-39 T 30-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CL1_1439 8786150d7f5c8744b0c57b83ac806f39 480 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 401 415 1.8E-16 T 30-10-2018 CL1_1439 8786150d7f5c8744b0c57b83ac806f39 480 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 441 448 1.8E-16 T 30-10-2018 CL1_1439 8786150d7f5c8744b0c57b83ac806f39 480 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 159 181 1.8E-16 T 30-10-2018 CL1_1439 8786150d7f5c8744b0c57b83ac806f39 480 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 298 323 1.8E-16 T 30-10-2018 CL1_1439 8786150d7f5c8744b0c57b83ac806f39 480 Gene3D G3DSA:3.50.50.60 294 480 6.9E-29 T 30-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily CL1_1439 8786150d7f5c8744b0c57b83ac806f39 480 Gene3D G3DSA:3.50.50.60 154 286 5.5E-37 T 30-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily CL1_1439 8786150d7f5c8744b0c57b83ac806f39 480 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 23 140 2.5E-38 T 30-10-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 CL1_1439 8786150d7f5c8744b0c57b83ac806f39 480 SUPERFAMILY SSF46548 8 168 1.57E-31 T 30-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 CL1_1439 8786150d7f5c8744b0c57b83ac806f39 480 Gene3D G3DSA:1.10.1060.10 3 151 2.6E-39 T 30-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 CL1_1439 8786150d7f5c8744b0c57b83ac806f39 480 TIGRFAM TIGR01316 gltA: glutamate synthase (NADPH), homotetrameric 18 472 2.8E-206 T 30-10-2018 IPR006004 Glutamate synthase (NADPH), homotetrameric KEGG: 00195+1.18.1.2|MetaCyc: PWY-101 CL1_1439 8786150d7f5c8744b0c57b83ac806f39 480 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 400 416 1.8E-23 T 30-10-2018 CL1_1439 8786150d7f5c8744b0c57b83ac806f39 480 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 298 316 1.8E-23 T 30-10-2018 CL1_1439 8786150d7f5c8744b0c57b83ac806f39 480 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 426 448 1.8E-23 T 30-10-2018 CL1_1439 8786150d7f5c8744b0c57b83ac806f39 480 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 160 179 1.8E-23 T 30-10-2018 CL1_0413 72011ea63710a8686d02fd9a0c178cd1 625 Pfam PF00821 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain 244 606 8.1E-107 T 30-10-2018 IPR035077 Phosphoenolpyruvate carboxykinase, GTP-utilising, C-terminal GO:0004611|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 CL1_0413 72011ea63710a8686d02fd9a0c178cd1 625 ProSitePatterns PS00505 Phosphoenolpyruvate carboxykinase (GTP) signature. 268 276 - T 30-10-2018 IPR018091 Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site GO:0004613 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 CL1_0413 72011ea63710a8686d02fd9a0c178cd1 625 Gene3D G3DSA:3.90.228.20 247 605 2.8E-147 T 30-10-2018 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 CL1_0413 72011ea63710a8686d02fd9a0c178cd1 625 Hamap MF_00452 Phosphoenolpyruvate carboxykinase [GTP] [pckG]. 18 607 36.617 T 30-10-2018 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 CL1_0413 72011ea63710a8686d02fd9a0c178cd1 625 PIRSF PIRSF001348 5 610 1.2E-209 T 30-10-2018 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 CL1_0413 72011ea63710a8686d02fd9a0c178cd1 625 Gene3D G3DSA:2.170.8.10 65 398 2.8E-147 T 30-10-2018 CL1_0413 72011ea63710a8686d02fd9a0c178cd1 625 SUPERFAMILY SSF68923 12 243 2.72E-61 T 30-10-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 CL1_0413 72011ea63710a8686d02fd9a0c178cd1 625 Pfam PF17297 Phosphoenolpyruvate carboxykinase N-terminal domain 30 239 8.1E-57 T 30-10-2018 IPR035078 Phosphoenolpyruvate carboxykinase, GTP-utilising, N-terminal GO:0004611|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 CL1_0413 72011ea63710a8686d02fd9a0c178cd1 625 Gene3D G3DSA:3.40.449.10 27 246 2.8E-147 T 30-10-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 CL1_0413 72011ea63710a8686d02fd9a0c178cd1 625 SUPERFAMILY SSF53795 244 606 2.2E-108 T 30-10-2018 CL1_0055 f2712f0cafbe5582fa9917f81e8016be 242 SUPERFAMILY SSF110849 14 241 3.53E-61 T 30-10-2018 IPR036086 ParB/Sulfiredoxin superfamily CL1_0055 f2712f0cafbe5582fa9917f81e8016be 242 Gene3D G3DSA:3.90.1530.10 17 238 2.1E-82 T 30-10-2018 CL1_0055 f2712f0cafbe5582fa9917f81e8016be 242 Pfam PF02195 ParB-like nuclease domain 22 92 1.1E-8 T 30-10-2018 IPR003115 ParB/Sulfiredoxin CL1_0055 f2712f0cafbe5582fa9917f81e8016be 242 Gene3D G3DSA:3.30.1760.10 98 227 2.1E-82 T 30-10-2018 IPR023098 ParB-like nuclease, C-terminal CL1_0055 f2712f0cafbe5582fa9917f81e8016be 242 SMART SM00470 19 114 1.0E-13 T 30-10-2018 IPR003115 ParB/Sulfiredoxin CL1_0700 415192dc0745c72ed35e46c6ef116463 451 SUPERFAMILY SSF48013 9 163 3.27E-24 T 30-10-2018 IPR035926 NusB-like superfamily CL1_0700 415192dc0745c72ed35e46c6ef116463 451 Gene3D G3DSA:1.10.940.10 6 150 6.1E-15 T 30-10-2018 IPR035926 NusB-like superfamily CL1_0700 415192dc0745c72ed35e46c6ef116463 451 Pfam PF01029 NusB family 10 133 3.1E-19 T 30-10-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CL1_0700 415192dc0745c72ed35e46c6ef116463 451 Gene3D G3DSA:3.40.50.150 154 450 7.6E-80 T 30-10-2018 CL1_0700 415192dc0745c72ed35e46c6ef116463 451 Pfam PF01189 16S rRNA methyltransferase RsmB/F 255 449 1.3E-49 T 30-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 CL1_0700 415192dc0745c72ed35e46c6ef116463 451 SUPERFAMILY SSF53335 148 450 1.42E-71 T 30-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CL1_0700 415192dc0745c72ed35e46c6ef116463 451 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 331 343 4.3E-21 T 30-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase CL1_0700 415192dc0745c72ed35e46c6ef116463 451 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 237 251 4.3E-21 T 30-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase CL1_0700 415192dc0745c72ed35e46c6ef116463 451 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 381 397 4.3E-21 T 30-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase CL1_0700 415192dc0745c72ed35e46c6ef116463 451 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 266 276 4.3E-21 T 30-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase CL1_0700 415192dc0745c72ed35e46c6ef116463 451 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 433 450 4.3E-21 T 30-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase CL1_1247 a058b24fcbc100f48fdc6edaf7000e57 395 SUPERFAMILY SSF52922 256 377 3.93E-35 T 30-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 CL1_1247 a058b24fcbc100f48fdc6edaf7000e57 395 SUPERFAMILY SSF52518 7 253 2.09E-70 T 30-10-2018 IPR029061 Thiamin diphosphate-binding fold CL1_1247 a058b24fcbc100f48fdc6edaf7000e57 395 Gene3D G3DSA:3.40.50.970 6 254 3.5E-99 T 30-10-2018 CL1_1247 a058b24fcbc100f48fdc6edaf7000e57 395 Gene3D G3DSA:3.40.50.920 255 395 3.8E-44 T 30-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 CL1_1247 a058b24fcbc100f48fdc6edaf7000e57 395 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 265 368 1.9E-33 T 30-10-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II CL1_1247 a058b24fcbc100f48fdc6edaf7000e57 395 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 19 241 5.3E-79 T 30-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 CL1_0862 77965fd0fe9e7b5459da5beba972f7fd 906 Pfam PF03477 ATP cone domain 5 93 2.6E-21 T 30-10-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 CL1_0862 77965fd0fe9e7b5459da5beba972f7fd 906 Pfam PF02867 Ribonucleotide reductase, barrel domain 271 771 2.6E-236 T 30-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CL1_0862 77965fd0fe9e7b5459da5beba972f7fd 906 Gene3D G3DSA:3.20.70.20 209 786 1.1E-203 T 30-10-2018 CL1_0862 77965fd0fe9e7b5459da5beba972f7fd 906 SUPERFAMILY SSF51998 270 782 2.87E-154 T 30-10-2018 CL1_0862 77965fd0fe9e7b5459da5beba972f7fd 906 Gene3D G3DSA:3.20.70.20 62 175 3.1E-6 T 30-10-2018 CL1_0862 77965fd0fe9e7b5459da5beba972f7fd 906 TIGRFAM TIGR02506 NrdE_NrdA: ribonucleoside-diphosphate reductase, alpha subunit 225 767 1.9E-111 T 30-10-2018 IPR013346 Ribonucleotide reductase, class I , alpha subunit GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CL1_0862 77965fd0fe9e7b5459da5beba972f7fd 906 PRINTS PR01183 Ribonucleotide reductase large chain signature 559 582 1.3E-30 T 30-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CL1_0862 77965fd0fe9e7b5459da5beba972f7fd 906 PRINTS PR01183 Ribonucleotide reductase large chain signature 346 365 1.3E-30 T 30-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CL1_0862 77965fd0fe9e7b5459da5beba972f7fd 906 PRINTS PR01183 Ribonucleotide reductase large chain signature 531 553 1.3E-30 T 30-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CL1_0862 77965fd0fe9e7b5459da5beba972f7fd 906 PRINTS PR01183 Ribonucleotide reductase large chain signature 493 516 1.3E-30 T 30-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CL1_0862 77965fd0fe9e7b5459da5beba972f7fd 906 PRINTS PR01183 Ribonucleotide reductase large chain signature 624 651 1.3E-30 T 30-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CL1_0862 77965fd0fe9e7b5459da5beba972f7fd 906 TIGRFAM TIGR02504 NrdJ_Z: ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent 120 780 1.3E-231 T 30-10-2018 IPR013344 Ribonucleotide reductase, adenosylcobalamin-dependent GO:0000166|GO:0004748|GO:0031419|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CL1_0862 77965fd0fe9e7b5459da5beba972f7fd 906 SUPERFAMILY SSF48168 9 150 3.66E-12 T 30-10-2018 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CL1_0862 77965fd0fe9e7b5459da5beba972f7fd 906 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 113 268 1.9E-28 T 30-10-2018 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CL1_1207 21a2ae6ce1600fdb847a7cfb1e506f44 420 PRINTS PR00419 Adrenodoxin reductase family signature 2 24 2.0E-5 T 30-10-2018 CL1_1207 21a2ae6ce1600fdb847a7cfb1e506f44 420 PRINTS PR00419 Adrenodoxin reductase family signature 25 38 2.0E-5 T 30-10-2018 CL1_1207 21a2ae6ce1600fdb847a7cfb1e506f44 420 Gene3D G3DSA:3.90.660.50 83 359 2.7E-140 T 30-10-2018 CL1_1207 21a2ae6ce1600fdb847a7cfb1e506f44 420 Gene3D G3DSA:3.50.50.60 4 403 2.7E-140 T 30-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily CL1_1207 21a2ae6ce1600fdb847a7cfb1e506f44 420 SUPERFAMILY SSF51905 1 281 9.99E-37 T 30-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily CL1_1207 21a2ae6ce1600fdb847a7cfb1e506f44 420 Pfam PF13450 NAD(P)-binding Rossmann-like domain 5 69 3.9E-13 T 30-10-2018 CL1_0856 94163e45a79cedb8012b35a493287619 352 Pfam PF00534 Glycosyl transferases group 1 188 346 1.0E-35 T 30-10-2018 IPR001296 Glycosyl transferase, family 1 CL1_0856 94163e45a79cedb8012b35a493287619 352 Pfam PF13439 Glycosyltransferase Family 4 17 167 2.6E-14 T 30-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 CL1_0856 94163e45a79cedb8012b35a493287619 352 Gene3D G3DSA:3.40.50.2000 1 186 2.2E-22 T 30-10-2018 CL1_0856 94163e45a79cedb8012b35a493287619 352 Gene3D G3DSA:3.40.50.2000 187 349 4.2E-41 T 30-10-2018 CL1_0856 94163e45a79cedb8012b35a493287619 352 SUPERFAMILY SSF53756 4 346 7.49E-68 T 30-10-2018 CL1_0352 fc9bb72db540927852334a0f76b1ebda 381 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 14 368 6.9E-122 T 30-10-2018 IPR017439 Amidohydrolase GO:0016787 CL1_0352 fc9bb72db540927852334a0f76b1ebda 381 Gene3D G3DSA:3.40.630.10 14 365 7.6E-147 T 30-10-2018 CL1_0352 fc9bb72db540927852334a0f76b1ebda 381 SUPERFAMILY SSF55031 177 285 1.01E-31 T 30-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain CL1_0352 fc9bb72db540927852334a0f76b1ebda 381 Gene3D G3DSA:3.30.70.360 176 290 7.6E-147 T 30-10-2018 CL1_0352 fc9bb72db540927852334a0f76b1ebda 381 SUPERFAMILY SSF53187 6 380 2.37E-88 T 30-10-2018 CL1_0352 fc9bb72db540927852334a0f76b1ebda 381 Pfam PF07687 Peptidase dimerisation domain 183 274 2.1E-9 T 30-10-2018 IPR011650 Peptidase M20, dimerisation domain CL1_0352 fc9bb72db540927852334a0f76b1ebda 381 Pfam PF01546 Peptidase family M20/M25/M40 68 375 1.1E-38 T 30-10-2018 IPR002933 Peptidase M20 GO:0016787 CL1_0352 fc9bb72db540927852334a0f76b1ebda 381 PIRSF PIRSF005962 1 381 2.4E-133 T 30-10-2018 IPR017439 Amidohydrolase GO:0016787 CL1_0953 ec4127e10a4535628382417fca5b0f0d 590 SMART SM00729 78 373 6.0E-50 T 30-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 CL1_0953 ec4127e10a4535628382417fca5b0f0d 590 SUPERFAMILY SSF55729 453 567 4.75E-10 T 30-10-2018 IPR016181 Acyl-CoA N-acyltransferase CL1_0953 ec4127e10a4535628382417fca5b0f0d 590 Pfam PF00583 Acetyltransferase (GNAT) family 465 560 8.9E-8 T 30-10-2018 IPR000182 GNAT domain CL1_0953 ec4127e10a4535628382417fca5b0f0d 590 TIGRFAM TIGR01211 ELP3: radical SAM enzyme/protein acetyltransferase, ELP3 family 15 571 1.6E-264 T 30-10-2018 IPR034687 Elongator complex protein 3-like Reactome: R-HSA-3214847 CL1_0953 ec4127e10a4535628382417fca5b0f0d 590 Pfam PF16199 Radical_SAM C-terminal domain 334 413 7.2E-27 T 30-10-2018 IPR032432 Radical SAM, C-terminal extension Reactome: R-HSA-3214847 CL1_0953 ec4127e10a4535628382417fca5b0f0d 590 Pfam PF04055 Radical SAM superfamily 85 318 9.8E-32 T 30-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CL1_0953 ec4127e10a4535628382417fca5b0f0d 590 Gene3D G3DSA:3.40.630.30 424 571 4.8E-8 T 30-10-2018 CL1_0953 ec4127e10a4535628382417fca5b0f0d 590 PIRSF PIRSF005669 1 572 1.1E-249 T 30-10-2018 IPR034687 Elongator complex protein 3-like Reactome: R-HSA-3214847 CL1_0953 ec4127e10a4535628382417fca5b0f0d 590 SUPERFAMILY SSF102114 83 380 4.05E-36 T 30-10-2018 CL1_0953 ec4127e10a4535628382417fca5b0f0d 590 Gene3D G3DSA:3.80.30.20 232 381 2.6E-13 T 30-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe CL1_1059 c018f2370b74decbf981054498c534d8 718 Pfam PF04042 DNA polymerase alpha/epsilon subunit B 452 655 2.3E-17 T 30-10-2018 IPR007185 DNA polymerase alpha/epsilon, subunit B GO:0003677|GO:0003887|GO:0006260 CL1_1059 c018f2370b74decbf981054498c534d8 718 Gene3D G3DSA:2.40.50.140 359 425 4.8E-5 T 30-10-2018 CL1_1059 c018f2370b74decbf981054498c534d8 718 Gene3D G3DSA:1.10.8.800 2 71 9.4E-23 T 30-10-2018 CL1_1059 c018f2370b74decbf981054498c534d8 718 SUPERFAMILY SSF56300 452 679 1.46E-18 T 30-10-2018 CL1_1059 c018f2370b74decbf981054498c534d8 718 Hamap MF_00325 DNA polymerase II small subunit [polB]. 2 708 32.411 T 30-10-2018 IPR011149 DNA polymerase II small subunit, archaeal GO:0003676|GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CL1_1059 c018f2370b74decbf981054498c534d8 718 Gene3D G3DSA:3.60.21.50 435 691 3.0E-25 T 30-10-2018 CL1_1059 c018f2370b74decbf981054498c534d8 718 PIRSF PIRSF000803 94 715 9.8E-176 T 30-10-2018 IPR011149 DNA polymerase II small subunit, archaeal GO:0003676|GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CL1_1921 86e28be0320c85de4f2e01fa8ec5ed3b 463 Pfam PF10117 McrBC 5-methylcytosine restriction system component 60 392 3.1E-42 T 30-10-2018 IPR019292 5-methylcytosine restriction system component CL1_1335 3c2ed348a76d2eb1b4b5fddff80649a2 322 SUPERFAMILY SSF102114 15 240 2.09E-36 T 30-10-2018 CL1_1335 3c2ed348a76d2eb1b4b5fddff80649a2 322 Pfam PF04055 Radical SAM superfamily 36 194 9.7E-11 T 30-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CL1_1335 3c2ed348a76d2eb1b4b5fddff80649a2 322 Gene3D G3DSA:3.20.20.70 13 242 8.9E-24 T 30-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CL1_1335 3c2ed348a76d2eb1b4b5fddff80649a2 322 SMART SM00729 27 235 5.1E-17 T 30-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 CL1_0349 d19803c687a6d73315e1edec36054c24 533 Pfam PF06418 CTP synthase N-terminus 3 265 3.1E-127 T 30-10-2018 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 CL1_0349 d19803c687a6d73315e1edec36054c24 533 SUPERFAMILY SSF52317 288 529 3.48E-80 T 30-10-2018 IPR029062 Class I glutamine amidotransferase-like CL1_0349 d19803c687a6d73315e1edec36054c24 533 Gene3D G3DSA:3.40.50.880 284 532 2.9E-108 T 30-10-2018 IPR029062 Class I glutamine amidotransferase-like CL1_0349 d19803c687a6d73315e1edec36054c24 533 TIGRFAM TIGR00337 PyrG: CTP synthase 2 525 1.2E-254 T 30-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 CL1_0349 d19803c687a6d73315e1edec36054c24 533 SUPERFAMILY SSF52540 3 265 6.84E-121 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_0349 d19803c687a6d73315e1edec36054c24 533 Gene3D G3DSA:3.40.50.300 1 283 1.8E-138 T 30-10-2018 CL1_0349 d19803c687a6d73315e1edec36054c24 533 Pfam PF00117 Glutamine amidotransferase class-I 300 524 1.2E-58 T 30-10-2018 IPR017926 Glutamine amidotransferase CL1_0349 d19803c687a6d73315e1edec36054c24 533 Hamap MF_01227 CTP synthase [pyrG]. 2 530 53.095 T 30-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 CL1_1473 efa5aabe9bf3cb9ef2367902f110900f 200 SUPERFAMILY SSF46785 18 76 1.16E-9 T 30-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CL1_1473 efa5aabe9bf3cb9ef2367902f110900f 200 Gene3D G3DSA:1.10.10.10 1 82 2.2E-22 T 30-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CL1_1473 efa5aabe9bf3cb9ef2367902f110900f 200 Pfam PF14544 Domain of unknown function (DUF4443) 80 191 1.3E-55 T 30-10-2018 IPR029349 Domain of unknown function DUF4443 CL1_1473 efa5aabe9bf3cb9ef2367902f110900f 200 Gene3D G3DSA:3.30.1360.30 83 191 1.1E-41 T 30-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 CL1_1473 efa5aabe9bf3cb9ef2367902f110900f 200 SUPERFAMILY SSF55261 88 198 1.14E-35 T 30-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 CL1_1841 968d2fc1ae949fd6ff378ab5b80033b7 53 Pfam PF00301 Rubredoxin 3 49 1.1E-25 T 30-10-2018 IPR024935 Rubredoxin domain GO:0005506 CL1_1841 968d2fc1ae949fd6ff378ab5b80033b7 53 ProSitePatterns PS00202 Rubredoxin signature. 33 43 - T 30-10-2018 IPR018527 Rubredoxin, iron-binding site GO:0046872 CL1_1841 968d2fc1ae949fd6ff378ab5b80033b7 53 PIRSF PIRSF000071 1 53 1.8E-28 T 30-10-2018 IPR024922 Rubredoxin GO:0005506|GO:0009055 CL1_1841 968d2fc1ae949fd6ff378ab5b80033b7 53 Gene3D G3DSA:2.20.28.10 2 53 1.3E-28 T 30-10-2018 CL1_1841 968d2fc1ae949fd6ff378ab5b80033b7 53 PRINTS PR00163 Rubredoxin signature 3 19 5.3E-12 T 30-10-2018 IPR024935 Rubredoxin domain GO:0005506 CL1_1841 968d2fc1ae949fd6ff378ab5b80033b7 53 PRINTS PR00163 Rubredoxin signature 33 49 5.3E-12 T 30-10-2018 IPR024935 Rubredoxin domain GO:0005506 CL1_1841 968d2fc1ae949fd6ff378ab5b80033b7 53 SUPERFAMILY SSF57802 1 53 6.73E-25 T 30-10-2018 CL1_2003 15d27fa3068fcefc1698a37ab4775928 176 SUPERFAMILY SSF55729 2 173 4.69E-44 T 30-10-2018 IPR016181 Acyl-CoA N-acyltransferase CL1_2003 15d27fa3068fcefc1698a37ab4775928 176 Pfam PF13302 Acetyltransferase (GNAT) domain 17 149 1.1E-28 T 30-10-2018 IPR000182 GNAT domain CL1_2003 15d27fa3068fcefc1698a37ab4775928 176 Gene3D G3DSA:3.40.630.30 4 173 4.1E-46 T 30-10-2018 CL1_0625 b375b4c3cad27e53c4ec31021a32dda1 239 Gene3D G3DSA:2.30.30.30 85 162 1.3E-29 T 30-10-2018 IPR014722 Ribosomal protein L2, domain 2 CL1_0625 b375b4c3cad27e53c4ec31021a32dda1 239 Gene3D G3DSA:4.10.950.10 163 239 3.4E-34 T 30-10-2018 IPR014726 Ribosomal protein L2, domain 3 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0625 b375b4c3cad27e53c4ec31021a32dda1 239 Hamap MF_01320_A 50S ribosomal protein L2 [rplB]. 1 238 42.235 T 30-10-2018 IPR023672 Ribosomal protein L2, archaeal-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0625 b375b4c3cad27e53c4ec31021a32dda1 239 PIRSF PIRSF002158 1 239 3.7E-73 T 30-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CL1_0625 b375b4c3cad27e53c4ec31021a32dda1 239 SMART SM01382 91 223 3.1E-61 T 30-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 CL1_0625 b375b4c3cad27e53c4ec31021a32dda1 239 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 92 222 4.4E-42 T 30-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 CL1_0625 b375b4c3cad27e53c4ec31021a32dda1 239 SUPERFAMILY SSF50104 94 237 1.87E-47 T 30-10-2018 IPR008991 Translation protein SH3-like domain superfamily CL1_0625 b375b4c3cad27e53c4ec31021a32dda1 239 SUPERFAMILY SSF50249 2 93 8.91E-24 T 30-10-2018 IPR012340 Nucleic acid-binding, OB-fold CL1_0625 b375b4c3cad27e53c4ec31021a32dda1 239 SMART SM01383 11 85 2.4E-25 T 30-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CL1_0625 b375b4c3cad27e53c4ec31021a32dda1 239 Gene3D G3DSA:2.40.50.140 1 81 5.0E-31 T 30-10-2018 CL1_0625 b375b4c3cad27e53c4ec31021a32dda1 239 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 11 84 7.3E-21 T 30-10-2018 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 CL1_1727 710eba8ae65d96f9af5905fcb27a79f5 530 SMART SM00220 191 436 1.9E-53 T 30-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CL1_1727 710eba8ae65d96f9af5905fcb27a79f5 530 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 197 219 - T 30-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 CL1_1727 710eba8ae65d96f9af5905fcb27a79f5 530 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 301 313 - T 30-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 CL1_1727 710eba8ae65d96f9af5905fcb27a79f5 530 Gene3D G3DSA:1.10.510.10 185 452 7.3E-65 T 30-10-2018 CL1_1727 710eba8ae65d96f9af5905fcb27a79f5 530 Pfam PF00069 Protein kinase domain 191 426 1.1E-45 T 30-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CL1_1727 710eba8ae65d96f9af5905fcb27a79f5 530 SUPERFAMILY SSF56112 185 433 1.91E-68 T 30-10-2018 IPR011009 Protein kinase-like domain superfamily CL1_0119 1756995bd5c645f2134cf2bf76d696f2 483 PRINTS PR01046 Prolyl-tRNA synthetase signature 65 83 2.1E-12 T 30-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 CL1_0119 1756995bd5c645f2134cf2bf76d696f2 483 PRINTS PR01046 Prolyl-tRNA synthetase signature 106 117 2.1E-12 T 30-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 CL1_0119 1756995bd5c645f2134cf2bf76d696f2 483 PRINTS PR01046 Prolyl-tRNA synthetase signature 146 157 2.1E-12 T 30-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 CL1_0119 1756995bd5c645f2134cf2bf76d696f2 483 PRINTS PR01046 Prolyl-tRNA synthetase signature 136 144 2.1E-12 T 30-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 CL1_0119 1756995bd5c645f2134cf2bf76d696f2 483 Pfam PF03129 Anticodon binding domain 290 384 3.6E-23 T 30-10-2018 IPR004154 Anticodon-binding CL1_0119 1756995bd5c645f2134cf2bf76d696f2 483 SMART SM00946 411 483 6.8E-26 T 30-10-2018 IPR016061 Proline-tRNA ligase, class II, C-terminal GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 CL1_0119 1756995bd5c645f2134cf2bf76d696f2 483 Gene3D G3DSA:3.30.930.10 12 283 7.2E-87 T 30-10-2018 CL1_0119 1756995bd5c645f2134cf2bf76d696f2 483 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 100 273 2.3E-24 T 30-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CL1_0119 1756995bd5c645f2134cf2bf76d696f2 483 Gene3D G3DSA:3.30.110.30 405 482 2.9E-19 T 30-10-2018 IPR017449 Prolyl-tRNA synthetase, class II GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 CL1_0119 1756995bd5c645f2134cf2bf76d696f2 483 TIGRFAM TIGR00408 proS_fam_I: proline--tRNA ligase 10 483 2.8E-181 T 30-10-2018 IPR004499 Proline-tRNA ligase, class IIa, archaeal-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 CL1_0119 1756995bd5c645f2134cf2bf76d696f2 483 SUPERFAMILY SSF64586 406 483 1.63E-21 T 30-10-2018 IPR017449 Prolyl-tRNA synthetase, class II GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 CL1_0119 1756995bd5c645f2134cf2bf76d696f2 483 Hamap MF_01571 Proline--tRNA ligase [proS]. 6 483 41.627 T 30-10-2018 IPR004499 Proline-tRNA ligase, class IIa, archaeal-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 CL1_0119 1756995bd5c645f2134cf2bf76d696f2 483 Pfam PF09180 Prolyl-tRNA synthetase, C-terminal 412 483 6.8E-16 T 30-10-2018 IPR016061 Proline-tRNA ligase, class II, C-terminal GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 CL1_0119 1756995bd5c645f2134cf2bf76d696f2 483 SUPERFAMILY SSF52954 278 403 3.78E-38 T 30-10-2018 CL1_0119 1756995bd5c645f2134cf2bf76d696f2 483 SUPERFAMILY SSF55681 11 277 2.49E-76 T 30-10-2018 CL1_0119 1756995bd5c645f2134cf2bf76d696f2 483 Gene3D G3DSA:3.40.50.800 284 402 4.0E-37 T 30-10-2018 IPR036621 Anticodon-binding domain superfamily CL1_0586 abfec86f158e455af806ecd83efd84f7 201 Pfam PF00318 Ribosomal protein S2 12 103 1.4E-10 T 30-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CL1_0586 abfec86f158e455af806ecd83efd84f7 201 Pfam PF00318 Ribosomal protein S2 110 174 8.1E-14 T 30-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CL1_0586 abfec86f158e455af806ecd83efd84f7 201 SUPERFAMILY SSF52313 3 192 1.03E-61 T 30-10-2018 IPR023591 Ribosomal protein S2, flavodoxin-like domain superfamily CL1_0586 abfec86f158e455af806ecd83efd84f7 201 TIGRFAM TIGR01012 uS2_euk_arch: ribosomal protein uS2 3 197 5.5E-99 T 30-10-2018 IPR005707 Ribosomal protein S2, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0586 abfec86f158e455af806ecd83efd84f7 201 Hamap MF_00291_A 30S ribosomal protein S2 [rpsB]. 1 198 48.322 T 30-10-2018 IPR023454 Ribosomal protein S2, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 CL1_0586 abfec86f158e455af806ecd83efd84f7 201 ProSitePatterns PS00963 Ribosomal protein S2 signature 2. 111 135 - T 30-10-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 CL1_0586 abfec86f158e455af806ecd83efd84f7 201 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 8 19 - T 30-10-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 CL1_0586 abfec86f158e455af806ecd83efd84f7 201 Gene3D G3DSA:3.40.50.10490 7 201 3.2E-71 T 30-10-2018 CL1_0586 abfec86f158e455af806ecd83efd84f7 201 PRINTS PR00395 Ribosomal protein S2 signature 128 139 5.1E-31 T 30-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CL1_0586 abfec86f158e455af806ecd83efd84f7 201 PRINTS PR00395 Ribosomal protein S2 signature 111 128 5.1E-31 T 30-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CL1_0586 abfec86f158e455af806ecd83efd84f7 201 PRINTS PR00395 Ribosomal protein S2 signature 8 26 5.1E-31 T 30-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CL1_0586 abfec86f158e455af806ecd83efd84f7 201 PRINTS PR00395 Ribosomal protein S2 signature 149 163 5.1E-31 T 30-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CL1_0586 abfec86f158e455af806ecd83efd84f7 201 PRINTS PR00395 Ribosomal protein S2 signature 86 103 5.1E-31 T 30-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CL1_0586 abfec86f158e455af806ecd83efd84f7 201 PRINTS PR00395 Ribosomal protein S2 signature 38 47 5.1E-31 T 30-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CL1_1145 5605919c6813acf50776db723a54bb8f 329 Pfam PF01226 Formate/nitrite transporter 11 257 1.8E-74 T 30-10-2018 IPR000292 Formate/nitrite transporter GO:0016020|GO:0022857|GO:0055085 CL1_1145 5605919c6813acf50776db723a54bb8f 329 Gene3D G3DSA:1.20.1080.10 8 270 1.6E-79 T 30-10-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 CL1_0791 4164b3f4a738acf51c906b0f2d3adb78 867 Pfam PF00271 Helicase conserved C-terminal domain 272 379 4.1E-16 T 30-10-2018 IPR001650 Helicase, C-terminal CL1_0791 4164b3f4a738acf51c906b0f2d3adb78 867 Pfam PF00270 DEAD/DEAH box helicase 34 218 1.4E-26 T 30-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CL1_0791 4164b3f4a738acf51c906b0f2d3adb78 867 PIRSF PIRSF037307 3 860 2.9E-286 T 30-10-2018 IPR017170 Lhr-like ATP-dependent RNA helicase, predicted GO:0005524|GO:0016818 CL1_0791 4164b3f4a738acf51c906b0f2d3adb78 867 SMART SM00490 297 383 1.6E-17 T 30-10-2018 IPR001650 Helicase, C-terminal CL1_0791 4164b3f4a738acf51c906b0f2d3adb78 867 Gene3D G3DSA:3.40.50.300 255 415 2.1E-25 T 30-10-2018 CL1_0791 4164b3f4a738acf51c906b0f2d3adb78 867 Gene3D G3DSA:3.40.50.300 12 233 1.2E-52 T 30-10-2018 CL1_0791 4164b3f4a738acf51c906b0f2d3adb78 867 SMART SM00487 29 254 1.5E-31 T 30-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CL1_0791 4164b3f4a738acf51c906b0f2d3adb78 867 SUPERFAMILY SSF52540 45 384 7.1E-46 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_0791 4164b3f4a738acf51c906b0f2d3adb78 867 Pfam PF08494 DEAD/H associated 637 824 9.5E-55 T 30-10-2018 IPR013701 DEAD/H associated GO:0005524|GO:0016818 CL1_0791 4164b3f4a738acf51c906b0f2d3adb78 867 SMART SM00382 46 423 0.0051 T 30-10-2018 IPR003593 AAA+ ATPase domain CL1_0154 5dfefbfaa8106a3a9d24d7d9f293504d 123 SUPERFAMILY SSF102712 3 121 3.66E-29 T 30-10-2018 CL1_0154 5dfefbfaa8106a3a9d24d7d9f293504d 123 Gene3D G3DSA:3.40.140.10 2 123 9.5E-28 T 30-10-2018 CL1_0154 5dfefbfaa8106a3a9d24d7d9f293504d 123 Pfam PF14464 Prokaryotic homologs of the JAB domain 10 103 1.0E-11 T 30-10-2018 IPR028090 JAB domain, prokaryotic CL1_0623 02fada1caa164d7e90eb1fbf0c33c48b 156 ProSitePatterns PS00464 Ribosomal protein L22 signature. 127 151 - T 30-10-2018 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0623 02fada1caa164d7e90eb1fbf0c33c48b 156 Pfam PF00237 Ribosomal protein L22p/L17e 21 151 5.2E-35 T 30-10-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 CL1_0623 02fada1caa164d7e90eb1fbf0c33c48b 156 TIGRFAM TIGR01038 uL22_arch_euk: ribosomal protein uL22 8 153 1.1E-66 T 30-10-2018 IPR005721 Ribosomal protein L22/L17, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0623 02fada1caa164d7e90eb1fbf0c33c48b 156 SUPERFAMILY SSF54843 8 153 8.76E-47 T 30-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 CL1_0623 02fada1caa164d7e90eb1fbf0c33c48b 156 Hamap MF_01331_A 50S ribosomal protein L22 [rplV]. 4 154 33.904 T 30-10-2018 IPR005721 Ribosomal protein L22/L17, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0623 02fada1caa164d7e90eb1fbf0c33c48b 156 Gene3D G3DSA:3.90.470.10 6 156 5.8E-53 T 30-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 CL1_0943 1c4dd379d0687402dd7d380177d7dbc5 248 PRINTS PR01874 DNA repair protein radA signature 14 42 9.8E-9 T 30-10-2018 CL1_0943 1c4dd379d0687402dd7d380177d7dbc5 248 PRINTS PR01874 DNA repair protein radA signature 56 73 9.8E-9 T 30-10-2018 CL1_0943 1c4dd379d0687402dd7d380177d7dbc5 248 PRINTS PR01874 DNA repair protein radA signature 167 195 9.8E-9 T 30-10-2018 CL1_0943 1c4dd379d0687402dd7d380177d7dbc5 248 Hamap MF_01076 UPF0273 protein . 2 245 63.154 T 30-10-2018 IPR022475 Uncharacterised protein family UPF0273, KaiC-like CL1_0943 1c4dd379d0687402dd7d380177d7dbc5 248 SUPERFAMILY SSF52540 3 236 7.27E-49 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_0943 1c4dd379d0687402dd7d380177d7dbc5 248 TIGRFAM TIGR03877 thermo_KaiC_1: KaiC domain protein, Ph0284 family 2 239 1.9E-141 T 30-10-2018 IPR022475 Uncharacterised protein family UPF0273, KaiC-like CL1_0943 1c4dd379d0687402dd7d380177d7dbc5 248 Gene3D G3DSA:3.40.50.300 1 247 1.1E-81 T 30-10-2018 CL1_0943 1c4dd379d0687402dd7d380177d7dbc5 248 Pfam PF06745 KaiC 5 237 2.4E-92 T 30-10-2018 IPR014774 KaiC-like domain CL1_0986 69555dddd108cbb040cbf54e4f1d15e2 83 Pfam PF14076 Domain of unknown function (DUF4258) 10 72 2.3E-16 T 30-10-2018 IPR025354 Protein of unknown function DUF4258 CL1_1119 98b8bfb063028f21b6624c46bebc16cb 225 PIRSF PIRSF001357 2 225 9.2E-92 T 30-10-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 CL1_1119 98b8bfb063028f21b6624c46bebc16cb 225 Gene3D G3DSA:3.20.20.70 2 224 1.5E-106 T 30-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CL1_1119 98b8bfb063028f21b6624c46bebc16cb 225 TIGRFAM TIGR00126 deoC: deoxyribose-phosphate aldolase 7 219 3.6E-91 T 30-10-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 CL1_1119 98b8bfb063028f21b6624c46bebc16cb 225 SMART SM01133 6 221 1.4E-116 T 30-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 CL1_1119 98b8bfb063028f21b6624c46bebc16cb 225 SUPERFAMILY SSF51569 4 221 2.93E-93 T 30-10-2018 CL1_1119 98b8bfb063028f21b6624c46bebc16cb 225 Pfam PF01791 DeoC/LacD family aldolase 10 218 2.4E-23 T 30-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 CL1_1119 98b8bfb063028f21b6624c46bebc16cb 225 Hamap MF_00114 Deoxyribose-phosphate aldolase [deoC]. 5 223 39.603 T 30-10-2018 IPR028581 Deoxyribose-phosphate aldolase type I GO:0004139 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180 CL1_1124 2f9bb6493cabf15455c16949565a3559 176 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 6 170 5.6E-14 T 30-10-2018 IPR007404 LexA-binding, inner membrane-associated putative hydrolase CL1_0086 6e5ed9f9b83abbbb81188e8ea275c617 334 PIRSF PIRSF000149 1 318 1.8E-87 T 30-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CL1_0086 6e5ed9f9b83abbbb81188e8ea275c617 334 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 146 296 3.4E-30 T 30-10-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CL1_0086 6e5ed9f9b83abbbb81188e8ea275c617 334 Hamap MF_00559 Glyceraldehyde-3-phosphate dehydrogenase [gap]. 1 334 190.693 T 30-10-2018 IPR006436 Glyceraldehyde-3-phosphate dehydrogenase, type II GO:0005737|GO:0006096|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.59|KEGG: 00710+1.2.1.59 CL1_0086 6e5ed9f9b83abbbb81188e8ea275c617 334 TIGRFAM TIGR01546 GAPDH-II_archae: glyceraldehyde-3-phosphate dehydrogenase, type II 5 333 4.9E-181 T 30-10-2018 IPR006436 Glyceraldehyde-3-phosphate dehydrogenase, type II GO:0005737|GO:0006096|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.59|KEGG: 00710+1.2.1.59 CL1_0086 6e5ed9f9b83abbbb81188e8ea275c617 334 SMART SM00846 3 141 1.4E-19 T 30-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CL1_0086 6e5ed9f9b83abbbb81188e8ea275c617 334 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 139 146 - T 30-10-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CL1_0086 6e5ed9f9b83abbbb81188e8ea275c617 334 Gene3D G3DSA:3.40.50.720 3 331 4.6E-148 T 30-10-2018 CL1_0086 6e5ed9f9b83abbbb81188e8ea275c617 334 SUPERFAMILY SSF51735 3 158 4.55E-48 T 30-10-2018 IPR036291 NAD(P)-binding domain superfamily CL1_0086 6e5ed9f9b83abbbb81188e8ea275c617 334 Gene3D G3DSA:3.30.360.10 140 301 4.6E-148 T 30-10-2018 CL1_0086 6e5ed9f9b83abbbb81188e8ea275c617 334 SUPERFAMILY SSF55347 140 301 1.5E-51 T 30-10-2018 CL1_0086 6e5ed9f9b83abbbb81188e8ea275c617 334 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 3 119 5.9E-13 T 30-10-2018 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CL1_1320 2b196d0a03f2b19a097a309c98d471e3 221 Gene3D G3DSA:3.40.50.300 7 220 4.7E-60 T 30-10-2018 CL1_1320 2b196d0a03f2b19a097a309c98d471e3 221 SMART SM00382 19 178 4.9E-5 T 30-10-2018 IPR003593 AAA+ ATPase domain CL1_1320 2b196d0a03f2b19a097a309c98d471e3 221 PIRSF PIRSF003336 1 220 4.4E-99 T 30-10-2018 IPR011939 DNA repair and recombination protein RadB GO:0003684|GO:0005524|GO:0006281|GO:0006310 CL1_1320 2b196d0a03f2b19a097a309c98d471e3 221 Hamap MF_00350 DNA repair and recombination protein RadB [radB]. 8 217 37.677 T 30-10-2018 IPR011939 DNA repair and recombination protein RadB GO:0003684|GO:0005524|GO:0006281|GO:0006310 CL1_1320 2b196d0a03f2b19a097a309c98d471e3 221 Pfam PF08423 Rad51 2 178 8.2E-30 T 30-10-2018 IPR013632 DNA recombination and repair protein Rad51-like, C-terminal Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579 CL1_1320 2b196d0a03f2b19a097a309c98d471e3 221 SUPERFAMILY SSF52540 2 220 9.87E-41 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_1320 2b196d0a03f2b19a097a309c98d471e3 221 TIGRFAM TIGR02237 recomb_radB: DNA repair and recombination protein RadB 9 217 1.2E-72 T 30-10-2018 IPR011939 DNA repair and recombination protein RadB GO:0003684|GO:0005524|GO:0006281|GO:0006310 CL1_1320 2b196d0a03f2b19a097a309c98d471e3 221 PRINTS PR01874 DNA repair protein radA signature 190 216 2.8E-8 T 30-10-2018 CL1_1320 2b196d0a03f2b19a097a309c98d471e3 221 PRINTS PR01874 DNA repair protein radA signature 11 39 2.8E-8 T 30-10-2018 CL1_0492 edad4bfca09ea560fe09292b241a430c 399 PIRSF PIRSF005572 15 399 2.0E-51 T 30-10-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 CL1_0492 edad4bfca09ea560fe09292b241a430c 399 Gene3D G3DSA:3.40.640.10 36 292 8.6E-145 T 30-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 CL1_0492 edad4bfca09ea560fe09292b241a430c 399 Pfam PF00266 Aminotransferase class-V 18 386 6.4E-138 T 30-10-2018 IPR000192 Aminotransferase class V domain CL1_0492 edad4bfca09ea560fe09292b241a430c 399 SUPERFAMILY SSF53383 5 397 7.56E-118 T 30-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase CL1_0492 edad4bfca09ea560fe09292b241a430c 399 Gene3D G3DSA:3.90.1150.10 16 387 8.6E-145 T 30-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 CL1_1453 cedd94d3d37cc4197a0ec4375b59e335 185 Hamap MF_01111 UPF0200 protein . 2 182 32.11 T 30-10-2018 IPR022970 Nucleoside triphosphate hydrolase-related CL1_1453 cedd94d3d37cc4197a0ec4375b59e335 185 SUPERFAMILY SSF52540 1 182 4.84E-19 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_1453 cedd94d3d37cc4197a0ec4375b59e335 185 Pfam PF13207 AAA domain 6 137 1.8E-18 T 30-10-2018 CL1_1453 cedd94d3d37cc4197a0ec4375b59e335 185 Gene3D G3DSA:3.40.50.300 1 183 6.8E-43 T 30-10-2018 CL1_0435 92b4e433b7095ba6a741a7ac000df3c4 431 SMART SM00770 1 256 7.9E-63 T 30-10-2018 IPR001531 Zinc-dependent phospholipase C GO:0004629|GO:0008270 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 CL1_0435 92b4e433b7095ba6a741a7ac000df3c4 431 SUPERFAMILY SSF48537 31 265 9.48E-38 T 30-10-2018 IPR008947 Phospholipase C/P1 nuclease domain superfamily GO:0016788 CL1_0435 92b4e433b7095ba6a741a7ac000df3c4 431 Gene3D G3DSA:1.10.575.10 23 170 1.2E-13 T 30-10-2018 IPR008947 Phospholipase C/P1 nuclease domain superfamily GO:0016788 CL1_0276 b2e7ba7e6327b2d568c51b35601a2883 593 TIGRFAM TIGR01564 S_layer_MJ: S-layer protein 276 590 4.7E-33 T 30-10-2018 IPR006454 S-layer protein GO:0005618 CL1_0276 b2e7ba7e6327b2d568c51b35601a2883 593 TIGRFAM TIGR01564 S_layer_MJ: S-layer protein 4 133 1.4E-32 T 30-10-2018 IPR006454 S-layer protein GO:0005618 CL1_0276 b2e7ba7e6327b2d568c51b35601a2883 593 Pfam PF05123 S-layer like family, N-terminal region 4 297 2.9E-46 T 30-10-2018 IPR022650 S-layer protein, N-terminal CL1_0276 b2e7ba7e6327b2d568c51b35601a2883 593 Pfam PF05124 S-layer like family, C-terminal region 361 590 4.4E-32 T 30-10-2018 IPR022651 S-layer protein, C-terminal CL1_0957 a3f51e157984fc538224c0867cce7cfa 913 SUPERFAMILY SSF55681 57 264 7.08E-58 T 30-10-2018 CL1_0957 a3f51e157984fc538224c0867cce7cfa 913 SMART SM00863 702 745 2.3E-17 T 30-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 CL1_0957 a3f51e157984fc538224c0867cce7cfa 913 SUPERFAMILY SSF55186 603 752 6.02E-48 T 30-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 CL1_0957 a3f51e157984fc538224c0867cce7cfa 913 Gene3D G3DSA:3.10.310.40 813 913 1.2E-20 T 30-10-2018 CL1_0957 a3f51e157984fc538224c0867cce7cfa 913 Gene3D G3DSA:2.40.30.130 502 599 3.8E-37 T 30-10-2018 CL1_0957 a3f51e157984fc538224c0867cce7cfa 913 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 61 893 2.0E-235 T 30-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CL1_0957 a3f51e157984fc538224c0867cce7cfa 913 Pfam PF02272 DHHA1 domain 782 910 4.6E-19 T 30-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 CL1_0957 a3f51e157984fc538224c0867cce7cfa 913 Hamap MF_00036_A Alanine--tRNA ligase [alaS]. 4 910 24.16 T 30-10-2018 IPR022429 Alanine-tRNA ligase, archaea GO:0000166|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 CL1_0957 a3f51e157984fc538224c0867cce7cfa 913 Gene3D G3DSA:3.30.980.10 605 674 1.0E-21 T 30-10-2018 CL1_0957 a3f51e157984fc538224c0867cce7cfa 913 PRINTS PR00980 Alanyl-tRNA synthetase signature 336 352 4.6E-22 T 30-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CL1_0957 a3f51e157984fc538224c0867cce7cfa 913 PRINTS PR00980 Alanyl-tRNA synthetase signature 127 138 4.6E-22 T 30-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CL1_0957 a3f51e157984fc538224c0867cce7cfa 913 PRINTS PR00980 Alanyl-tRNA synthetase signature 360 373 4.6E-22 T 30-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CL1_0957 a3f51e157984fc538224c0867cce7cfa 913 PRINTS PR00980 Alanyl-tRNA synthetase signature 245 258 4.6E-22 T 30-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CL1_0957 a3f51e157984fc538224c0867cce7cfa 913 PRINTS PR00980 Alanyl-tRNA synthetase signature 206 217 4.6E-22 T 30-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CL1_0957 a3f51e157984fc538224c0867cce7cfa 913 SUPERFAMILY SSF101353 305 501 5.36E-50 T 30-10-2018 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain superfamily GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 CL1_0957 a3f51e157984fc538224c0867cce7cfa 913 Gene3D G3DSA:3.30.930.10 1 260 5.8E-114 T 30-10-2018 CL1_0957 a3f51e157984fc538224c0867cce7cfa 913 SUPERFAMILY SSF50447 512 597 5.65E-19 T 30-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily CL1_0957 a3f51e157984fc538224c0867cce7cfa 913 Gene3D G3DSA:3.30.54.20 675 726 1.1E-28 T 30-10-2018 CL1_0957 a3f51e157984fc538224c0867cce7cfa 913 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 702 744 9.1E-15 T 30-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 CL1_0957 a3f51e157984fc538224c0867cce7cfa 913 TIGRFAM TIGR03683 A-tRNA_syn_arch: alanine--tRNA ligase 4 911 0.0 T 30-10-2018 IPR022429 Alanine-tRNA ligase, archaea GO:0000166|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 CL1_0957 a3f51e157984fc538224c0867cce7cfa 913 Pfam PF01411 tRNA synthetases class II (A) 61 603 6.0E-162 T 30-10-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 CL1_0818 08103263252c0782b44a6d1cabcd7c0d 614 Pfam PF13597 Anaerobic ribonucleoside-triphosphate reductase 22 612 1.4E-152 T 30-10-2018 IPR012833 Ribonucleoside-triphosphate reductase, anaerobic GO:0006260|GO:0008998|GO:0016491|GO:0055114 KEGG: 00230+1.1.98.6|KEGG: 00240+1.1.98.6|MetaCyc: PWY-7187|MetaCyc: PWY-7220|MetaCyc: PWY-7222 CL1_0818 08103263252c0782b44a6d1cabcd7c0d 614 SUPERFAMILY SSF51998 23 596 2.29E-128 T 30-10-2018 CL1_0818 08103263252c0782b44a6d1cabcd7c0d 614 TIGRFAM TIGR02487 NrdD: anaerobic ribonucleoside-triphosphate reductase 22 611 6.1E-161 T 30-10-2018 IPR012833 Ribonucleoside-triphosphate reductase, anaerobic GO:0006260|GO:0008998|GO:0016491|GO:0055114 KEGG: 00230+1.1.98.6|KEGG: 00240+1.1.98.6|MetaCyc: PWY-7187|MetaCyc: PWY-7220|MetaCyc: PWY-7222 CL1_0818 08103263252c0782b44a6d1cabcd7c0d 614 Gene3D G3DSA:3.20.70.20 33 594 1.1E-70 T 30-10-2018 CL1_1275 01990f6505acdc71ff1b3763f68a020e 705 SUPERFAMILY SSF51445 24 420 2.25E-83 T 30-10-2018 IPR017853 Glycoside hydrolase superfamily CL1_1275 01990f6505acdc71ff1b3763f68a020e 705 SUPERFAMILY SSF81296 505 577 2.49E-13 T 30-10-2018 IPR014756 Immunoglobulin E-set CL1_1275 01990f6505acdc71ff1b3763f68a020e 705 Pfam PF16657 Maltogenic Amylase, C-terminal domain 423 496 4.6E-9 T 30-10-2018 IPR032091 Maltogenic Amylase, C-terminal CL1_1275 01990f6505acdc71ff1b3763f68a020e 705 PRINTS PR00110 Alpha-amylase signature 329 341 2.5E-5 T 30-10-2018 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 CL1_1275 01990f6505acdc71ff1b3763f68a020e 705 PRINTS PR00110 Alpha-amylase signature 234 245 2.5E-5 T 30-10-2018 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 CL1_1275 01990f6505acdc71ff1b3763f68a020e 705 PRINTS PR00110 Alpha-amylase signature 133 144 2.5E-5 T 30-10-2018 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 CL1_1275 01990f6505acdc71ff1b3763f68a020e 705 SUPERFAMILY SSF51011 423 502 4.32E-16 T 30-10-2018 CL1_1275 01990f6505acdc71ff1b3763f68a020e 705 SMART SM00642 31 414 2.4E-82 T 30-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CL1_1275 01990f6505acdc71ff1b3763f68a020e 705 SMART SM00632 426 502 0.0032 T 30-10-2018 IPR031319 Alpha-amylase, C-terminal domain Reactome: R-HSA-189085 CL1_1275 01990f6505acdc71ff1b3763f68a020e 705 Gene3D G3DSA:2.60.40.10 504 581 5.6E-15 T 30-10-2018 IPR013783 Immunoglobulin-like fold CL1_1275 01990f6505acdc71ff1b3763f68a020e 705 Pfam PF01833 IPT/TIG domain 506 584 8.8E-10 T 30-10-2018 IPR002909 IPT domain CL1_1275 01990f6505acdc71ff1b3763f68a020e 705 Pfam PF00128 Alpha amylase, catalytic domain 62 382 4.2E-55 T 30-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CL1_1275 01990f6505acdc71ff1b3763f68a020e 705 Gene3D G3DSA:3.20.20.80 23 416 5.7E-108 T 30-10-2018 CL1_1275 01990f6505acdc71ff1b3763f68a020e 705 Gene3D G3DSA:2.60.40.1180 417 500 2.2E-12 T 30-10-2018 IPR013780 Glycosyl hydrolase, all-beta CL1_1275 01990f6505acdc71ff1b3763f68a020e 705 TIGRFAM TIGR04288 CGP_CTERM: CGP-CTERM domain 685 704 6.9E-5 T 30-10-2018 IPR027552 CGP-CTERM domain CL1_0076 763337d07b2909dbc74e7c2234cc1cca 137 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 58 73 3.7E-7 T 30-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CL1_0076 763337d07b2909dbc74e7c2234cc1cca 137 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 90 105 3.7E-7 T 30-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CL1_0076 763337d07b2909dbc74e7c2234cc1cca 137 SMART SM00418 56 134 1.5E-11 T 30-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CL1_0076 763337d07b2909dbc74e7c2234cc1cca 137 Gene3D G3DSA:1.10.10.10 38 136 6.3E-19 T 30-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CL1_0076 763337d07b2909dbc74e7c2234cc1cca 137 SUPERFAMILY SSF46785 48 123 3.87E-18 T 30-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CL1_0076 763337d07b2909dbc74e7c2234cc1cca 137 Pfam PF01022 Bacterial regulatory protein, arsR family 63 109 4.1E-13 T 30-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CL1_1387 a0cd96382876451d4178e647a0766ee2 166 SUPERFAMILY SSF52317 1 165 4.59E-52 T 30-10-2018 IPR029062 Class I glutamine amidotransferase-like CL1_1387 a0cd96382876451d4178e647a0766ee2 166 Gene3D G3DSA:3.40.50.880 1 166 6.5E-53 T 30-10-2018 IPR029062 Class I glutamine amidotransferase-like CL1_1387 a0cd96382876451d4178e647a0766ee2 166 Pfam PF01965 DJ-1/PfpI family 1 163 7.1E-58 T 30-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 CL1_1387 a0cd96382876451d4178e647a0766ee2 166 TIGRFAM TIGR01382 PfpI: intracellular protease, PfpI family 2 165 2.4E-67 T 30-10-2018 IPR006286 Deglycase PfpI CL1_0407 bcf0ca5f2b000f4720132d5bf9820af1 424 SUPERFAMILY SSF102114 154 375 7.19E-39 T 30-10-2018 CL1_0407 bcf0ca5f2b000f4720132d5bf9820af1 424 Gene3D G3DSA:3.80.30.20 163 391 5.0E-37 T 30-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe CL1_0407 bcf0ca5f2b000f4720132d5bf9820af1 424 Gene3D G3DSA:3.40.50.280 3 125 1.5E-25 T 30-10-2018 CL1_0407 bcf0ca5f2b000f4720132d5bf9820af1 424 SMART SM00729 164 382 1.5E-47 T 30-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 CL1_0407 bcf0ca5f2b000f4720132d5bf9820af1 424 TIGRFAM TIGR04013 B12_SAM_MJ_1487: B12-binding domain/radical SAM domain protein, MJ_1487 family 4 392 6.4E-142 T 30-10-2018 IPR023980 Conserved hypothetical protein CHP04013, B12-binding/radical SAM-type CL1_0407 bcf0ca5f2b000f4720132d5bf9820af1 424 Pfam PF04055 Radical SAM superfamily 168 337 4.1E-24 T 30-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CL1_0407 bcf0ca5f2b000f4720132d5bf9820af1 424 Pfam PF02310 B12 binding domain 17 111 6.9E-8 T 30-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CL1_0019 f9a515d1fb4b59573411bf95eb4ea931 301 SMART SM00962 104 299 1.9E-114 T 30-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CL1_0019 f9a515d1fb4b59573411bf95eb4ea931 301 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 25 298 1.6E-109 T 30-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 CL1_0019 f9a515d1fb4b59573411bf95eb4ea931 301 SUPERFAMILY SSF52540 101 301 1.56E-56 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_0019 f9a515d1fb4b59573411bf95eb4ea931 301 Gene3D G3DSA:3.40.50.300 90 298 1.5E-86 T 30-10-2018 CL1_0019 f9a515d1fb4b59573411bf95eb4ea931 301 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 24 299 59.141 T 30-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 CL1_0019 f9a515d1fb4b59573411bf95eb4ea931 301 Pfam PF00448 SRP54-type protein, GTPase domain 104 298 2.6E-80 T 30-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CL1_0019 f9a515d1fb4b59573411bf95eb4ea931 301 Pfam PF02881 SRP54-type protein, helical bundle domain 5 79 5.7E-14 T 30-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CL1_0019 f9a515d1fb4b59573411bf95eb4ea931 301 SMART SM00963 1 85 4.8E-17 T 30-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CL1_0019 f9a515d1fb4b59573411bf95eb4ea931 301 Gene3D G3DSA:1.20.120.140 2 87 1.5E-22 T 30-10-2018 CL1_0019 f9a515d1fb4b59573411bf95eb4ea931 301 SUPERFAMILY SSF47364 1 89 1.01E-17 T 30-10-2018 IPR036225 SRP/SRP receptor, N-terminal Reactome: R-HSA-1799339 CL1_0019 f9a515d1fb4b59573411bf95eb4ea931 301 SMART SM00382 103 298 1.3E-8 T 30-10-2018 IPR003593 AAA+ ATPase domain CL1_0019 f9a515d1fb4b59573411bf95eb4ea931 301 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 272 285 - T 30-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CL1_0877 a761cd50bb60a5401dd6d4b4bd6e1fed 125 Pfam PF01850 PIN domain 4 114 8.9E-13 T 30-10-2018 IPR002716 PIN domain CL1_0877 a761cd50bb60a5401dd6d4b4bd6e1fed 125 SUPERFAMILY SSF88723 3 121 1.51E-27 T 30-10-2018 IPR029060 PIN-like domain superfamily CL1_0877 a761cd50bb60a5401dd6d4b4bd6e1fed 125 SMART SM00670 1 112 8.3E-9 T 30-10-2018 IPR002716 PIN domain CL1_0877 a761cd50bb60a5401dd6d4b4bd6e1fed 125 Gene3D G3DSA:3.40.50.1010 2 125 2.1E-26 T 30-10-2018 CL1_0654 0c616309385a0727e09810f36bf04b61 522 Pfam PF01039 Carboxyl transferase domain 28 520 2.5E-202 T 30-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 CL1_0654 0c616309385a0727e09810f36bf04b61 522 SUPERFAMILY SSF52096 244 522 1.06E-92 T 30-10-2018 IPR029045 ClpP/crotonase-like domain superfamily CL1_0654 0c616309385a0727e09810f36bf04b61 522 SUPERFAMILY SSF52096 2 251 7.85E-79 T 30-10-2018 IPR029045 ClpP/crotonase-like domain superfamily CL1_0654 0c616309385a0727e09810f36bf04b61 522 Gene3D G3DSA:3.90.226.10 262 522 5.8E-96 T 30-10-2018 CL1_0654 0c616309385a0727e09810f36bf04b61 522 Gene3D G3DSA:3.90.226.10 1 260 5.9E-98 T 30-10-2018 CL1_0796 d48b90f8951996397e76f6f213fa8e98 335 Hamap MF_01824 Pyridoxal 5'-phosphate synthase subunit PdxS [pdxS]. 10 335 53.537 T 30-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CL1_0796 d48b90f8951996397e76f6f213fa8e98 335 Pfam PF05690 Thiazole biosynthesis protein ThiG 247 299 2.7E-8 T 30-10-2018 IPR033983 Thiazole synthase ThiG KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 CL1_0796 d48b90f8951996397e76f6f213fa8e98 335 ProSitePatterns PS01235 PdxS/SNZ family signature. 248 266 - T 30-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CL1_0796 d48b90f8951996397e76f6f213fa8e98 335 Pfam PF01680 SOR/SNZ family 13 214 1.7E-95 T 30-10-2018 IPR033755 PdxS/SNZ N-terminal domain KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CL1_0796 d48b90f8951996397e76f6f213fa8e98 335 PIRSF PIRSF029271 4 335 8.7E-148 T 30-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CL1_0796 d48b90f8951996397e76f6f213fa8e98 335 SUPERFAMILY SSF51366 24 310 1.93E-61 T 30-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 CL1_0796 d48b90f8951996397e76f6f213fa8e98 335 TIGRFAM TIGR00343 TIGR00343: pyridoxal 5'-phosphate synthase, synthase subunit Pdx1 15 334 6.6E-146 T 30-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CL1_0796 d48b90f8951996397e76f6f213fa8e98 335 Gene3D G3DSA:3.20.20.70 1 316 9.9E-153 T 30-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CL1_0638 b7086896fbc6f21abbbf28ae12122050 952 Gene3D G3DSA:3.30.70.20 613 694 1.8E-13 T 30-10-2018 CL1_0638 b7086896fbc6f21abbbf28ae12122050 952 SUPERFAMILY SSF54862 580 694 2.3E-19 T 30-10-2018 CL1_0638 b7086896fbc6f21abbbf28ae12122050 952 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 98 176 1.4E-18 T 30-10-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 CL1_0638 b7086896fbc6f21abbbf28ae12122050 952 PRINTS PR00419 Adrenodoxin reductase family signature 354 367 5.0E-22 T 30-10-2018 CL1_0638 b7086896fbc6f21abbbf28ae12122050 952 PRINTS PR00419 Adrenodoxin reductase family signature 213 226 5.0E-22 T 30-10-2018 CL1_0638 b7086896fbc6f21abbbf28ae12122050 952 PRINTS PR00419 Adrenodoxin reductase family signature 255 265 5.0E-22 T 30-10-2018 CL1_0638 b7086896fbc6f21abbbf28ae12122050 952 PRINTS PR00419 Adrenodoxin reductase family signature 190 212 5.0E-22 T 30-10-2018 CL1_0638 b7086896fbc6f21abbbf28ae12122050 952 PRINTS PR00419 Adrenodoxin reductase family signature 321 335 5.0E-22 T 30-10-2018 CL1_0638 b7086896fbc6f21abbbf28ae12122050 952 SUPERFAMILY SSF51971 187 429 3.0E-75 T 30-10-2018 CL1_0638 b7086896fbc6f21abbbf28ae12122050 952 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 1 73 6.7E-11 T 30-10-2018 CL1_0638 b7086896fbc6f21abbbf28ae12122050 952 ProSitePatterns PS00641 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. 31 48 - T 30-10-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CL1_0638 b7086896fbc6f21abbbf28ae12122050 952 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 189 482 2.7E-42 T 30-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CL1_0638 b7086896fbc6f21abbbf28ae12122050 952 SUPERFAMILY SSF53706 703 939 1.08E-17 T 30-10-2018 CL1_0638 b7086896fbc6f21abbbf28ae12122050 952 Gene3D G3DSA:3.50.50.60 316 515 1.9E-31 T 30-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily CL1_0638 b7086896fbc6f21abbbf28ae12122050 952 Gene3D G3DSA:3.50.50.60 186 313 8.8E-38 T 30-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily CL1_0638 b7086896fbc6f21abbbf28ae12122050 952 SUPERFAMILY SSF46548 96 199 1.62E-21 T 30-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 CL1_0638 b7086896fbc6f21abbbf28ae12122050 952 Gene3D G3DSA:3.10.20.740 1 115 8.7E-26 T 30-10-2018 CL1_0638 b7086896fbc6f21abbbf28ae12122050 952 SUPERFAMILY SSF54292 1 97 1.8E-25 T 30-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 CL1_1228 c296f7cd48fde0972ec9e7582cd41a81 278 SUPERFAMILY SSF52402 152 276 1.17E-21 T 30-10-2018 CL1_1228 c296f7cd48fde0972ec9e7582cd41a81 278 Gene3D G3DSA:3.40.50.620 1 145 2.9E-29 T 30-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CL1_1228 c296f7cd48fde0972ec9e7582cd41a81 278 SUPERFAMILY SSF52402 1 133 2.68E-25 T 30-10-2018 CL1_1228 c296f7cd48fde0972ec9e7582cd41a81 278 PRINTS PR01438 Universal stress protein signature 236 248 1.1E-16 T 30-10-2018 IPR006015 Universal stress protein A CL1_1228 c296f7cd48fde0972ec9e7582cd41a81 278 PRINTS PR01438 Universal stress protein signature 2 20 1.1E-16 T 30-10-2018 IPR006015 Universal stress protein A CL1_1228 c296f7cd48fde0972ec9e7582cd41a81 278 PRINTS PR01438 Universal stress protein signature 254 276 1.1E-16 T 30-10-2018 IPR006015 Universal stress protein A CL1_1228 c296f7cd48fde0972ec9e7582cd41a81 278 Gene3D G3DSA:3.40.50.620 148 278 1.3E-23 T 30-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CL1_1228 c296f7cd48fde0972ec9e7582cd41a81 278 Pfam PF00582 Universal stress protein family 191 276 1.3E-14 T 30-10-2018 IPR006016 UspA CL1_1228 c296f7cd48fde0972ec9e7582cd41a81 278 Pfam PF00582 Universal stress protein family 1 133 2.6E-18 T 30-10-2018 IPR006016 UspA CL1_0482 1ca5f7e6297f83fe1011e2e82be3168e 243 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 17 231 1.7E-53 T 30-10-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 CL1_0482 1ca5f7e6297f83fe1011e2e82be3168e 243 Gene3D G3DSA:3.40.50.300 1 224 6.0E-64 T 30-10-2018 CL1_0482 1ca5f7e6297f83fe1011e2e82be3168e 243 Hamap MF_02040 Iron-sulfur cluster carrier protein. 9 237 27.406 T 30-10-2018 IPR019591 Mrp/NBP35 ATP-binding protein CL1_0482 1ca5f7e6297f83fe1011e2e82be3168e 243 SUPERFAMILY SSF52540 16 219 5.4E-40 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_0595 42fdca809dda118adc41723a4d792849 180 Hamap MF_01306_A 30S ribosomal protein S4 [rpsD]. 1 156 34.373 T 30-10-2018 IPR022802 Ribosomal protein S4, archaeal GO:0006412|GO:0019843 CL1_0595 42fdca809dda118adc41723a4d792849 180 SMART SM01390 5 102 5.8E-7 T 30-10-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 CL1_0595 42fdca809dda118adc41723a4d792849 180 SUPERFAMILY SSF55174 9 160 1.39E-33 T 30-10-2018 CL1_0595 42fdca809dda118adc41723a4d792849 180 Gene3D G3DSA:3.10.290.10 104 176 4.2E-17 T 30-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 CL1_0595 42fdca809dda118adc41723a4d792849 180 SMART SM00363 103 165 2.1E-15 T 30-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0595 42fdca809dda118adc41723a4d792849 180 ProSitePatterns PS00632 Ribosomal protein S4 signature. 101 125 - T 30-10-2018 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0595 42fdca809dda118adc41723a4d792849 180 TIGRFAM TIGR01018 uS4_arch: ribosomal protein uS4 1 161 2.5E-76 T 30-10-2018 IPR005710 Ribosomal protein S4/S9, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0595 42fdca809dda118adc41723a4d792849 180 Pfam PF01479 S4 domain 103 148 1.9E-17 T 30-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_2035 a4b030d066cc12c4f86d5aff9cd571fa 235 SUPERFAMILY SSF53681 4 117 1.08E-36 T 30-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CL1_2035 a4b030d066cc12c4f86d5aff9cd571fa 235 Gene3D G3DSA:3.40.50.1860 6 220 2.4E-89 T 30-10-2018 CL1_2035 a4b030d066cc12c4f86d5aff9cd571fa 235 Gene3D G3DSA:3.40.50.1860 107 214 2.4E-89 T 30-10-2018 CL1_2035 a4b030d066cc12c4f86d5aff9cd571fa 235 Pfam PF01177 Asp/Glu/Hydantoin racemase 9 222 2.2E-64 T 30-10-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CL1_2035 a4b030d066cc12c4f86d5aff9cd571fa 235 TIGRFAM TIGR00035 asp_race: aspartate racemase 3 234 2.9E-107 T 30-10-2018 IPR004380 Aspartate racemase GO:0006520|GO:0016855 CL1_2035 a4b030d066cc12c4f86d5aff9cd571fa 235 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 81 89 - T 30-10-2018 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CL1_2035 a4b030d066cc12c4f86d5aff9cd571fa 235 SUPERFAMILY SSF53681 119 227 6.54E-27 T 30-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CL1_0788 0ed925faaf66ac9d778bdaab72a631d6 334 SUPERFAMILY SSF56042 166 326 2.09E-43 T 30-10-2018 IPR036676 PurM-like, C-terminal domain superfamily CL1_0788 0ed925faaf66ac9d778bdaab72a631d6 334 Pfam PF00586 AIR synthase related protein, N-terminal domain 57 159 2.8E-18 T 30-10-2018 IPR016188 PurM-like, N-terminal domain CL1_0788 0ed925faaf66ac9d778bdaab72a631d6 334 Gene3D G3DSA:3.30.1330.10 2 165 3.4E-52 T 30-10-2018 IPR036921 PurM-like, N-terminal domain superfamily CL1_0788 0ed925faaf66ac9d778bdaab72a631d6 334 Gene3D G3DSA:3.90.650.10 166 332 5.3E-50 T 30-10-2018 IPR036676 PurM-like, C-terminal domain superfamily CL1_0788 0ed925faaf66ac9d778bdaab72a631d6 334 SUPERFAMILY SSF55326 2 165 1.5E-39 T 30-10-2018 IPR036921 PurM-like, N-terminal domain superfamily CL1_0788 0ed925faaf66ac9d778bdaab72a631d6 334 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 2 321 3.7E-123 T 30-10-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CL1_0788 0ed925faaf66ac9d778bdaab72a631d6 334 Pfam PF02769 AIR synthase related protein, C-terminal domain 171 326 1.6E-25 T 30-10-2018 IPR010918 PurM-like, C-terminal domain CL1_0788 0ed925faaf66ac9d778bdaab72a631d6 334 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 2 330 37.714 T 30-10-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CL1_1489 a417c1bc9d24d6f05c3d761977b7fa34 198 Gene3D G3DSA:1.10.10.10 4 105 8.7E-28 T 30-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CL1_1489 a417c1bc9d24d6f05c3d761977b7fa34 198 SMART SM00418 9 89 1.5E-17 T 30-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CL1_1489 a417c1bc9d24d6f05c3d761977b7fa34 198 Pfam PF01022 Bacterial regulatory protein, arsR family 16 61 4.0E-13 T 30-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CL1_1489 a417c1bc9d24d6f05c3d761977b7fa34 198 SUPERFAMILY SSF46785 6 173 2.68E-28 T 30-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CL1_1763 d5a91742a03ff31b885944decfb1d487 354 Gene3D G3DSA:1.10.10.10 283 354 2.6E-18 T 30-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CL1_1763 d5a91742a03ff31b885944decfb1d487 354 Gene3D G3DSA:3.40.50.300 1 205 1.6E-37 T 30-10-2018 CL1_1763 d5a91742a03ff31b885944decfb1d487 354 SUPERFAMILY SSF52540 1 280 6.66E-40 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_1763 d5a91742a03ff31b885944decfb1d487 354 Gene3D G3DSA:1.10.8.60 207 282 1.5E-25 T 30-10-2018 CL1_1763 d5a91742a03ff31b885944decfb1d487 354 SUPERFAMILY SSF46785 284 354 1.16E-17 T 30-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CL1_1763 d5a91742a03ff31b885944decfb1d487 354 Pfam PF01637 ATPase domain predominantly from Archaea 15 245 1.2E-13 T 30-10-2018 IPR011579 ATPase domain GO:0005524 CL1_0918 0267233da41d4065d4b4640c2466b0f4 410 Gene3D G3DSA:3.20.20.140 44 407 5.3E-107 T 30-10-2018 CL1_0918 0267233da41d4065d4b4640c2466b0f4 410 SUPERFAMILY SSF51338 3 398 2.88E-23 T 30-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 CL1_0918 0267233da41d4065d4b4640c2466b0f4 410 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 14 391 4.7E-120 T 30-10-2018 CL1_0918 0267233da41d4065d4b4640c2466b0f4 410 Hamap MF_00220_A Dihydroorotase [pyrC]. 4 396 64.412 T 30-10-2018 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CL1_0918 0267233da41d4065d4b4640c2466b0f4 410 Pfam PF01979 Amidohydrolase family 274 388 1.0E-8 T 30-10-2018 IPR006680 Amidohydrolase-related GO:0016787 CL1_0918 0267233da41d4065d4b4640c2466b0f4 410 Pfam PF01979 Amidohydrolase family 49 207 2.8E-11 T 30-10-2018 IPR006680 Amidohydrolase-related GO:0016787 CL1_0918 0267233da41d4065d4b4640c2466b0f4 410 ProSitePatterns PS00482 Dihydroorotase signature 1. 56 64 - T 30-10-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CL1_0918 0267233da41d4065d4b4640c2466b0f4 410 ProSitePatterns PS00483 Dihydroorotase signature 2. 275 286 - T 30-10-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CL1_0918 0267233da41d4065d4b4640c2466b0f4 410 SUPERFAMILY SSF51556 53 335 7.21E-74 T 30-10-2018 IPR032466 Metal-dependent hydrolase CL1_0631 97c97296cb57060edaa603fbb3f8027c 182 Gene3D G3DSA:3.90.1170.10 1 181 9.2E-65 T 30-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 CL1_0631 97c97296cb57060edaa603fbb3f8027c 182 ProSitePatterns PS01257 Ribosomal protein L10e signature. 105 126 - T 30-10-2018 IPR018255 Ribosomal protein L10e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0631 97c97296cb57060edaa603fbb3f8027c 182 Hamap MF_00448 50S ribosomal protein L10e [rpl10e]. 1 174 36.881 T 30-10-2018 IPR022981 Ribosomal protein L10e, archaea CL1_0631 97c97296cb57060edaa603fbb3f8027c 182 PIRSF PIRSF005590 1 180 9.7E-70 T 30-10-2018 IPR001197 Ribosomal protein L10e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0631 97c97296cb57060edaa603fbb3f8027c 182 Pfam PF00252 Ribosomal protein L16p/L10e 14 160 7.0E-33 T 30-10-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 CL1_0631 97c97296cb57060edaa603fbb3f8027c 182 SUPERFAMILY SSF54686 4 168 4.06E-56 T 30-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 CL1_1359 4181e4d6e9f72377daf137fbf3806914 477 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 21 139 8.8E-39 T 30-10-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 CL1_1359 4181e4d6e9f72377daf137fbf3806914 477 SUPERFAMILY SSF51971 157 405 4.65E-72 T 30-10-2018 CL1_1359 4181e4d6e9f72377daf137fbf3806914 477 TIGRFAM TIGR01316 gltA: glutamate synthase (NADPH), homotetrameric 17 470 8.0E-215 T 30-10-2018 IPR006004 Glutamate synthase (NADPH), homotetrameric KEGG: 00195+1.18.1.2|MetaCyc: PWY-101 CL1_1359 4181e4d6e9f72377daf137fbf3806914 477 SUPERFAMILY SSF46548 8 166 2.46E-31 T 30-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 CL1_1359 4181e4d6e9f72377daf137fbf3806914 477 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 158 177 5.6E-25 T 30-10-2018 CL1_1359 4181e4d6e9f72377daf137fbf3806914 477 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 241 259 5.6E-25 T 30-10-2018 CL1_1359 4181e4d6e9f72377daf137fbf3806914 477 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 424 446 5.6E-25 T 30-10-2018 CL1_1359 4181e4d6e9f72377daf137fbf3806914 477 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 296 314 5.6E-25 T 30-10-2018 CL1_1359 4181e4d6e9f72377daf137fbf3806914 477 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 397 413 5.6E-25 T 30-10-2018 CL1_1359 4181e4d6e9f72377daf137fbf3806914 477 Gene3D G3DSA:1.10.1060.10 6 148 1.8E-38 T 30-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 CL1_1359 4181e4d6e9f72377daf137fbf3806914 477 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 296 321 1.7E-17 T 30-10-2018 CL1_1359 4181e4d6e9f72377daf137fbf3806914 477 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 439 446 1.7E-17 T 30-10-2018 CL1_1359 4181e4d6e9f72377daf137fbf3806914 477 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 398 412 1.7E-17 T 30-10-2018 CL1_1359 4181e4d6e9f72377daf137fbf3806914 477 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 157 179 1.7E-17 T 30-10-2018 CL1_1359 4181e4d6e9f72377daf137fbf3806914 477 Gene3D G3DSA:3.40.50.720 152 265 3.8E-26 T 30-10-2018 CL1_1359 4181e4d6e9f72377daf137fbf3806914 477 Gene3D G3DSA:3.50.50.60 266 405 1.4E-47 T 30-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily CL1_1359 4181e4d6e9f72377daf137fbf3806914 477 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 157 455 2.1E-42 T 30-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CL1_0793 f38227a3263b8c636392d39dce4718b8 444 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 4 437 44.638 T 30-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 CL1_0793 f38227a3263b8c636392d39dce4718b8 444 SUPERFAMILY SSF56235 5 240 1.63E-54 T 30-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CL1_0793 f38227a3263b8c636392d39dce4718b8 444 Gene3D G3DSA:3.40.50.2020 258 422 3.3E-146 T 30-10-2018 CL1_0793 f38227a3263b8c636392d39dce4718b8 444 Pfam PF00156 Phosphoribosyl transferase domain 272 369 2.2E-7 T 30-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CL1_0793 f38227a3263b8c636392d39dce4718b8 444 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 5 438 3.4E-161 T 30-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 CL1_0793 f38227a3263b8c636392d39dce4718b8 444 Pfam PF13537 Glutamine amidotransferase domain 72 199 3.2E-18 T 30-10-2018 IPR017932 Glutamine amidotransferase type 2 domain CL1_0793 f38227a3263b8c636392d39dce4718b8 444 PIRSF PIRSF000485 1 441 1.5E-159 T 30-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 CL1_0793 f38227a3263b8c636392d39dce4718b8 444 Gene3D G3DSA:3.60.20.10 5 438 3.3E-146 T 30-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CL1_0793 f38227a3263b8c636392d39dce4718b8 444 SUPERFAMILY SSF53271 233 439 1.84E-67 T 30-10-2018 IPR029057 Phosphoribosyltransferase-like CL1_1896 2cffef8c4557704c5cb9f9992b6415ba 478 Gene3D G3DSA:3.40.1380.20 337 474 6.3E-168 T 30-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CL1_1896 2cffef8c4557704c5cb9f9992b6415ba 478 Gene3D G3DSA:3.20.20.60 7 336 6.3E-168 T 30-10-2018 CL1_1896 2cffef8c4557704c5cb9f9992b6415ba 478 Pfam PF02887 Pyruvate kinase, alpha/beta domain 368 475 1.6E-24 T 30-10-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CL1_1896 2cffef8c4557704c5cb9f9992b6415ba 478 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 6 478 5.7E-171 T 30-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CL1_1896 2cffef8c4557704c5cb9f9992b6415ba 478 Gene3D G3DSA:2.40.33.10 74 170 6.3E-168 T 30-10-2018 IPR015806 Pyruvate kinase, insert domain superfamily GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CL1_1896 2cffef8c4557704c5cb9f9992b6415ba 478 SUPERFAMILY SSF52935 324 478 1.44E-32 T 30-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CL1_1896 2cffef8c4557704c5cb9f9992b6415ba 478 SUPERFAMILY SSF51621 4 340 1.05E-95 T 30-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 CL1_1896 2cffef8c4557704c5cb9f9992b6415ba 478 ProSitePatterns PS00110 Pyruvate kinase active site signature. 216 228 - T 30-10-2018 IPR018209 Pyruvate kinase, active site GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CL1_1896 2cffef8c4557704c5cb9f9992b6415ba 478 PRINTS PR01050 Pyruvate kinase family signature 188 202 1.1E-64 T 30-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CL1_1896 2cffef8c4557704c5cb9f9992b6415ba 478 PRINTS PR01050 Pyruvate kinase family signature 63 79 1.1E-64 T 30-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CL1_1896 2cffef8c4557704c5cb9f9992b6415ba 478 PRINTS PR01050 Pyruvate kinase family signature 295 313 1.1E-64 T 30-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CL1_1896 2cffef8c4557704c5cb9f9992b6415ba 478 PRINTS PR01050 Pyruvate kinase family signature 218 244 1.1E-64 T 30-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CL1_1896 2cffef8c4557704c5cb9f9992b6415ba 478 PRINTS PR01050 Pyruvate kinase family signature 245 269 1.1E-64 T 30-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CL1_1896 2cffef8c4557704c5cb9f9992b6415ba 478 PRINTS PR01050 Pyruvate kinase family signature 270 294 1.1E-64 T 30-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CL1_1896 2cffef8c4557704c5cb9f9992b6415ba 478 PRINTS PR01050 Pyruvate kinase family signature 314 330 1.1E-64 T 30-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CL1_1896 2cffef8c4557704c5cb9f9992b6415ba 478 Pfam PF00224 Pyruvate kinase, barrel domain 6 338 7.5E-120 T 30-10-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CL1_1896 2cffef8c4557704c5cb9f9992b6415ba 478 SUPERFAMILY SSF50800 75 166 2.09E-24 T 30-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily CL1_0546 1316254e2d0dbb35e8518c06a5a80545 663 SUPERFAMILY SSF88688 416 531 1.11E-30 T 30-10-2018 IPR028995 Glycoside hydrolase families 57/38, central domain superfamily CL1_0546 1316254e2d0dbb35e8518c06a5a80545 663 Pfam PF03065 Glycosyl hydrolase family 57 6 387 1.6E-70 T 30-10-2018 IPR004300 Glycoside hydrolase family 57, N-terminal domain GO:0003824|GO:0005975 CL1_0546 1316254e2d0dbb35e8518c06a5a80545 663 Gene3D G3DSA:3.20.110.10 1 416 6.5E-180 T 30-10-2018 IPR027291 Glycoside hydrolase 38, N-terminal domain superfamily CL1_0546 1316254e2d0dbb35e8518c06a5a80545 663 Gene3D G3DSA:1.10.150.20 609 663 9.8E-14 T 30-10-2018 CL1_0546 1316254e2d0dbb35e8518c06a5a80545 663 Gene3D G3DSA:1.20.1430.10 417 563 1.5E-57 T 30-10-2018 IPR037090 Glycoside hydrolase families 57, central domain KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900 CL1_0546 1316254e2d0dbb35e8518c06a5a80545 663 Pfam PF09210 Domain of unknown function (DUF1957) 427 526 3.8E-27 T 30-10-2018 IPR015293 Domain of unknown function DUF1957 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900 CL1_0546 1316254e2d0dbb35e8518c06a5a80545 663 SUPERFAMILY SSF88713 3 416 3.52E-118 T 30-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CL1_0546 1316254e2d0dbb35e8518c06a5a80545 663 SUPERFAMILY SSF47794 610 661 5.65E-8 T 30-10-2018 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 CL1_0546 1316254e2d0dbb35e8518c06a5a80545 663 Pfam PF14520 Helix-hairpin-helix domain 610 656 7.0E-10 T 30-10-2018 CL1_1819 ffd8bc689231c00cbbd2fa7ce4aa0b2a 331 SUPERFAMILY SSF143437 35 132 1.74E-8 T 30-10-2018 CL1_1819 ffd8bc689231c00cbbd2fa7ce4aa0b2a 331 SMART SM00981 56 141 2.2E-6 T 30-10-2018 IPR004114 THUMP domain GO:0003723 CL1_1819 ffd8bc689231c00cbbd2fa7ce4aa0b2a 331 TIGRFAM TIGR01177 TIGR01177: putative methyltransferase, TIGR01177 family 3 327 6.1E-101 T 30-10-2018 IPR005885 tRNA guanine(10)-N2-dimethyltransferase GO:0004809|GO:0030488 CL1_1819 ffd8bc689231c00cbbd2fa7ce4aa0b2a 331 Pfam PF02926 THUMP domain 48 133 1.4E-10 T 30-10-2018 IPR004114 THUMP domain GO:0003723 CL1_1819 ffd8bc689231c00cbbd2fa7ce4aa0b2a 331 Gene3D G3DSA:3.30.2130.30 10 142 3.4E-5 T 30-10-2018 CL1_1819 ffd8bc689231c00cbbd2fa7ce4aa0b2a 331 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 250 256 - T 30-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CL1_1819 ffd8bc689231c00cbbd2fa7ce4aa0b2a 331 SUPERFAMILY SSF53335 157 298 9.81E-27 T 30-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CL1_1819 ffd8bc689231c00cbbd2fa7ce4aa0b2a 331 Pfam PF01170 Putative RNA methylase family UPF0020 156 297 8.6E-26 T 30-10-2018 IPR000241 Putative RNA methylase domain CL1_1819 ffd8bc689231c00cbbd2fa7ce4aa0b2a 331 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 269 293 6.9E-8 T 30-10-2018 CL1_1819 ffd8bc689231c00cbbd2fa7ce4aa0b2a 331 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 183 197 6.9E-8 T 30-10-2018 CL1_1819 ffd8bc689231c00cbbd2fa7ce4aa0b2a 331 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 247 259 6.9E-8 T 30-10-2018 CL1_1819 ffd8bc689231c00cbbd2fa7ce4aa0b2a 331 Gene3D G3DSA:3.40.50.150 153 331 1.8E-31 T 30-10-2018 CL1_1948 a45ae2915320442d6a0ea5c31ec37912 591 Pfam PF00005 ABC transporter 361 482 2.1E-20 T 30-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CL1_1948 a45ae2915320442d6a0ea5c31ec37912 591 Pfam PF04068 Possible Fer4-like domain in RNase L inhibitor, RLI 1 32 1.2E-11 T 30-10-2018 IPR007209 RNase L inhibitor RLI, possible metal-binding domain CL1_1948 a45ae2915320442d6a0ea5c31ec37912 591 SMART SM00382 98 286 3.6E-10 T 30-10-2018 IPR003593 AAA+ ATPase domain CL1_1948 a45ae2915320442d6a0ea5c31ec37912 591 SMART SM00382 363 531 1.8E-10 T 30-10-2018 IPR003593 AAA+ ATPase domain CL1_1948 a45ae2915320442d6a0ea5c31ec37912 591 SUPERFAMILY SSF52540 96 285 4.28E-34 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_1948 a45ae2915320442d6a0ea5c31ec37912 591 ProSitePatterns PS00211 ABC transporters family signature. 211 225 - T 30-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CL1_1948 a45ae2915320442d6a0ea5c31ec37912 591 SUPERFAMILY SSF54862 4 124 1.95E-24 T 30-10-2018 CL1_1948 a45ae2915320442d6a0ea5c31ec37912 591 Pfam PF00037 4Fe-4S binding domain 44 67 4.3E-7 T 30-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CL1_1948 a45ae2915320442d6a0ea5c31ec37912 591 PRINTS PR01868 ABC transporter family E signature 103 128 1.1E-62 T 30-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 CL1_1948 a45ae2915320442d6a0ea5c31ec37912 591 PRINTS PR01868 ABC transporter family E signature 134 150 1.1E-62 T 30-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 CL1_1948 a45ae2915320442d6a0ea5c31ec37912 591 PRINTS PR01868 ABC transporter family E signature 48 72 1.1E-62 T 30-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 CL1_1948 a45ae2915320442d6a0ea5c31ec37912 591 PRINTS PR01868 ABC transporter family E signature 150 176 1.1E-62 T 30-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 CL1_1948 a45ae2915320442d6a0ea5c31ec37912 591 PRINTS PR01868 ABC transporter family E signature 20 35 1.1E-62 T 30-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 CL1_1948 a45ae2915320442d6a0ea5c31ec37912 591 PRINTS PR01868 ABC transporter family E signature 75 95 1.1E-62 T 30-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 CL1_1948 a45ae2915320442d6a0ea5c31ec37912 591 Pfam PF00005 ABC transporter 96 238 4.9E-17 T 30-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CL1_1948 a45ae2915320442d6a0ea5c31ec37912 591 Gene3D G3DSA:3.40.50.300 327 589 5.3E-66 T 30-10-2018 CL1_1948 a45ae2915320442d6a0ea5c31ec37912 591 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 51 62 - T 30-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CL1_1948 a45ae2915320442d6a0ea5c31ec37912 591 SUPERFAMILY SSF52540 360 529 7.19E-40 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_1948 a45ae2915320442d6a0ea5c31ec37912 591 Gene3D G3DSA:3.40.50.300 1 326 2.2E-102 T 30-10-2018 CL1_0479 072be1c532a10131089538c5d9418d76 206 Pfam PF01925 Sulfite exporter TauE/SafE 2 198 8.5E-37 T 30-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 CL1_0479 072be1c532a10131089538c5d9418d76 206 SUPERFAMILY SSF103473 33 178 2.35E-5 T 30-10-2018 IPR036259 MFS transporter superfamily CL1_1777 48c50ceab2bf4eba742eec85cec6fa20 451 PRINTS PR00145 Argininosuccinate lyase family signature 272 288 2.6E-11 T 30-10-2018 CL1_1777 48c50ceab2bf4eba742eec85cec6fa20 451 PRINTS PR00145 Argininosuccinate lyase family signature 227 251 2.6E-11 T 30-10-2018 CL1_1777 48c50ceab2bf4eba742eec85cec6fa20 451 PRINTS PR00145 Argininosuccinate lyase family signature 136 156 2.6E-11 T 30-10-2018 CL1_1777 48c50ceab2bf4eba742eec85cec6fa20 451 PRINTS PR00145 Argininosuccinate lyase family signature 95 117 2.6E-11 T 30-10-2018 CL1_1777 48c50ceab2bf4eba742eec85cec6fa20 451 Gene3D G3DSA:1.10.275.10 1 100 1.0E-36 T 30-10-2018 IPR024083 Fumarase/histidase, N-terminal CL1_1777 48c50ceab2bf4eba742eec85cec6fa20 451 Gene3D G3DSA:1.10.40.30 360 449 3.0E-22 T 30-10-2018 CL1_1777 48c50ceab2bf4eba742eec85cec6fa20 451 ProSitePatterns PS00163 Fumarate lyases signature. 272 281 - T 30-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 CL1_1777 48c50ceab2bf4eba742eec85cec6fa20 451 Pfam PF10397 Adenylosuccinate lyase C-terminus 362 438 3.4E-19 T 30-10-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CL1_1777 48c50ceab2bf4eba742eec85cec6fa20 451 SUPERFAMILY SSF48557 4 443 5.03E-135 T 30-10-2018 IPR008948 L-Aspartase-like GO:0003824 CL1_1777 48c50ceab2bf4eba742eec85cec6fa20 451 Gene3D G3DSA:1.20.200.10 101 359 2.1E-96 T 30-10-2018 CL1_1777 48c50ceab2bf4eba742eec85cec6fa20 451 Pfam PF00206 Lyase 13 293 8.0E-58 T 30-10-2018 IPR022761 Fumarate lyase, N-terminal CL1_1777 48c50ceab2bf4eba742eec85cec6fa20 451 PRINTS PR00149 Fumarate lyase superfamily signature 227 254 5.9E-27 T 30-10-2018 IPR000362 Fumarate lyase family CL1_1777 48c50ceab2bf4eba742eec85cec6fa20 451 PRINTS PR00149 Fumarate lyase superfamily signature 96 114 5.9E-27 T 30-10-2018 IPR000362 Fumarate lyase family CL1_1777 48c50ceab2bf4eba742eec85cec6fa20 451 PRINTS PR00149 Fumarate lyase superfamily signature 141 159 5.9E-27 T 30-10-2018 IPR000362 Fumarate lyase family CL1_1777 48c50ceab2bf4eba742eec85cec6fa20 451 PRINTS PR00149 Fumarate lyase superfamily signature 272 288 5.9E-27 T 30-10-2018 IPR000362 Fumarate lyase family CL1_1777 48c50ceab2bf4eba742eec85cec6fa20 451 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 6 438 8.9E-186 T 30-10-2018 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CL1_1777 48c50ceab2bf4eba742eec85cec6fa20 451 SMART SM00998 360 439 7.1E-30 T 30-10-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CL1_1517 1aa3939856be2032f2384a4248e5676e 323 PIRSF PIRSF002849 2 320 2.8E-127 T 30-10-2018 CL1_1517 1aa3939856be2032f2384a4248e5676e 323 Gene3D G3DSA:3.40.50.300 22 188 6.1E-46 T 30-10-2018 CL1_1517 1aa3939856be2032f2384a4248e5676e 323 Gene3D G3DSA:1.10.8.300 206 315 1.4E-31 T 30-10-2018 CL1_1517 1aa3939856be2032f2384a4248e5676e 323 SUPERFAMILY SSF52540 8 290 1.38E-46 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_1517 1aa3939856be2032f2384a4248e5676e 323 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 42 171 8.1E-65 T 30-10-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 CL1_0444 61b12e5e9c0dca07b30a924ffed8a683 145 SUPERFAMILY SSF54814 76 141 2.29E-7 T 30-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 CL1_0444 61b12e5e9c0dca07b30a924ffed8a683 145 Gene3D G3DSA:3.30.300.20 2 73 1.7E-26 T 30-10-2018 IPR015946 K homology domain-like, alpha/beta CL1_0444 61b12e5e9c0dca07b30a924ffed8a683 145 Hamap MF_00945_A Transcription termination/antitermination protein NusA [nusA]. 1 145 30.026 T 30-10-2018 IPR010212 Probable transcription termination protein NusA, archaeal CL1_0444 61b12e5e9c0dca07b30a924ffed8a683 145 SUPERFAMILY SSF54814 13 74 1.83E-11 T 30-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 CL1_0444 61b12e5e9c0dca07b30a924ffed8a683 145 TIGRFAM TIGR01952 nusA_arch: NusA family KH domain protein, archaeal 1 145 8.9E-60 T 30-10-2018 IPR010212 Probable transcription termination protein NusA, archaeal CL1_0444 61b12e5e9c0dca07b30a924ffed8a683 145 Gene3D G3DSA:3.30.300.20 74 144 1.2E-22 T 30-10-2018 IPR015946 K homology domain-like, alpha/beta CL1_0444 61b12e5e9c0dca07b30a924ffed8a683 145 Pfam PF07650 KH domain 14 94 5.6E-17 T 30-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_1263 42dd1c6406fce9e2e6f426b1de1c615e 169 Gene3D G3DSA:3.20.130.10 1 169 5.5E-66 T 30-10-2018 IPR036660 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain superfamily GO:0016836 CL1_1263 42dd1c6406fce9e2e6f426b1de1c615e 169 TIGRFAM TIGR00723 ttdB_fumA_fumB: hydrolyase, tartrate beta subunit/fumarate domain protein, Fe-S type 10 169 7.2E-58 T 30-10-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 CL1_1263 42dd1c6406fce9e2e6f426b1de1c615e 169 Pfam PF05683 Fumarase C-terminus 2 168 3.7E-39 T 30-10-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 CL1_1263 42dd1c6406fce9e2e6f426b1de1c615e 169 SUPERFAMILY SSF117457 3 168 2.75E-53 T 30-10-2018 IPR036660 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain superfamily GO:0016836 CL1_0652 57750cfb47851d1c13e26d48b4f8a974 2019 SUPERFAMILY SSF51294 330 803 3.43E-43 T 30-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CL1_0652 57750cfb47851d1c13e26d48b4f8a974 2019 SMART SM00530 700 751 5.7E-4 T 30-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CL1_0652 57750cfb47851d1c13e26d48b4f8a974 2019 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 1370 1392 2.2E-8 T 30-10-2018 IPR030934 Intein C-terminal splicing region CL1_0652 57750cfb47851d1c13e26d48b4f8a974 2019 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 782 804 1.2E-8 T 30-10-2018 IPR030934 Intein C-terminal splicing region CL1_0652 57750cfb47851d1c13e26d48b4f8a974 2019 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 1728 1750 5.8E-5 T 30-10-2018 IPR030934 Intein C-terminal splicing region CL1_0652 57750cfb47851d1c13e26d48b4f8a974 2019 Pfam PF00493 MCM2/3/5 family 1392 1415 6.9E-7 T 30-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 CL1_0652 57750cfb47851d1c13e26d48b4f8a974 2019 Pfam PF00493 MCM2/3/5 family 261 331 4.1E-22 T 30-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 CL1_0652 57750cfb47851d1c13e26d48b4f8a974 2019 Pfam PF00493 MCM2/3/5 family 797 860 5.1E-19 T 30-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 CL1_0652 57750cfb47851d1c13e26d48b4f8a974 2019 Pfam PF00493 MCM2/3/5 family 1748 1929 3.6E-64 T 30-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 CL1_0652 57750cfb47851d1c13e26d48b4f8a974 2019 SMART SM00350 96 1930 1.9E-21 T 30-10-2018 IPR031327 Mini-chromosome maintenance protein CL1_0652 57750cfb47851d1c13e26d48b4f8a974 2019 Gene3D G3DSA:3.30.1640.10 1 95 3.9E-34 T 30-10-2018 CL1_0652 57750cfb47851d1c13e26d48b4f8a974 2019 Pfam PF14528 LAGLIDADG-like domain 587 668 7.0E-21 T 30-10-2018 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 CL1_0652 57750cfb47851d1c13e26d48b4f8a974 2019 Pfam PF14528 LAGLIDADG-like domain 491 560 3.4E-5 T 30-10-2018 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 CL1_0652 57750cfb47851d1c13e26d48b4f8a974 2019 Gene3D G3DSA:2.170.16.10 1688 1746 9.1E-9 T 30-10-2018 CL1_0652 57750cfb47851d1c13e26d48b4f8a974 2019 Gene3D G3DSA:3.10.28.10 1074 1256 5.9E-17 T 30-10-2018 IPR027434 Homing endonuclease CL1_0652 57750cfb47851d1c13e26d48b4f8a974 2019 Gene3D G3DSA:3.10.28.10 484 664 1.8E-32 T 30-10-2018 IPR027434 Homing endonuclease CL1_0652 57750cfb47851d1c13e26d48b4f8a974 2019 Pfam PF17207 MCM OB domain 100 225 1.1E-35 T 30-10-2018 IPR033762 MCM OB domain Reactome: R-HSA-176187|Reactome: R-HSA-176974|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962 CL1_0652 57750cfb47851d1c13e26d48b4f8a974 2019 Pfam PF01381 Helix-turn-helix 704 749 5.1E-5 T 30-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CL1_0652 57750cfb47851d1c13e26d48b4f8a974 2019 Gene3D G3DSA:2.20.28.10 127 171 2.7E-29 T 30-10-2018 CL1_0652 57750cfb47851d1c13e26d48b4f8a974 2019 Pfam PF14890 Intein splicing domain 373 803 4.6E-38 T 30-10-2018 CL1_0652 57750cfb47851d1c13e26d48b4f8a974 2019 SMART SM00305 1351 1397 2.5E-13 T 30-10-2018 IPR003586 Hint domain C-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CL1_0652 57750cfb47851d1c13e26d48b4f8a974 2019 SMART SM00305 1707 1755 1.8E-5 T 30-10-2018 IPR003586 Hint domain C-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CL1_0652 57750cfb47851d1c13e26d48b4f8a974 2019 SMART SM00305 762 809 2.7E-16 T 30-10-2018 IPR003586 Hint domain C-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CL1_0652 57750cfb47851d1c13e26d48b4f8a974 2019 Gene3D G3DSA:2.170.16.10 332 475 1.8E-36 T 30-10-2018 CL1_0652 57750cfb47851d1c13e26d48b4f8a974 2019 Gene3D G3DSA:2.170.16.10 1421 1566 8.9E-36 T 30-10-2018 CL1_0652 57750cfb47851d1c13e26d48b4f8a974 2019 Gene3D G3DSA:2.40.50.140 172 252 1.3E-26 T 30-10-2018 CL1_0652 57750cfb47851d1c13e26d48b4f8a974 2019 SUPERFAMILY SSF55608 573 679 1.26E-17 T 30-10-2018 IPR027434 Homing endonuclease CL1_0652 57750cfb47851d1c13e26d48b4f8a974 2019 Gene3D G3DSA:1.10.10.10 1934 2019 3.2E-14 T 30-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CL1_0652 57750cfb47851d1c13e26d48b4f8a974 2019 PRINTS PR00379 Intein signature 415 428 9.6E-19 T 30-10-2018 IPR006142 Intein GO:0016539 CL1_0652 57750cfb47851d1c13e26d48b4f8a974 2019 PRINTS PR00379 Intein signature 780 797 9.6E-19 T 30-10-2018 IPR006142 Intein GO:0016539 CL1_0652 57750cfb47851d1c13e26d48b4f8a974 2019 PRINTS PR00379 Intein signature 488 500 9.6E-19 T 30-10-2018 IPR006142 Intein GO:0016539 CL1_0652 57750cfb47851d1c13e26d48b4f8a974 2019 PRINTS PR00379 Intein signature 587 599 9.6E-19 T 30-10-2018 IPR006142 Intein GO:0016539 CL1_0652 57750cfb47851d1c13e26d48b4f8a974 2019 PRINTS PR00379 Intein signature 615 630 9.6E-19 T 30-10-2018 IPR006142 Intein GO:0016539 CL1_0652 57750cfb47851d1c13e26d48b4f8a974 2019 SUPERFAMILY SSF52540 1748 1926 8.59E-22 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_0652 57750cfb47851d1c13e26d48b4f8a974 2019 SMART SM00306 857 973 1.8E-15 T 30-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CL1_0652 57750cfb47851d1c13e26d48b4f8a974 2019 SMART SM00306 1413 1535 7.7E-22 T 30-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CL1_0652 57750cfb47851d1c13e26d48b4f8a974 2019 SMART SM00306 329 452 1.3E-30 T 30-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CL1_0652 57750cfb47851d1c13e26d48b4f8a974 2019 Gene3D G3DSA:2.170.16.10 1264 1386 5.1E-11 T 30-10-2018 CL1_0652 57750cfb47851d1c13e26d48b4f8a974 2019 SUPERFAMILY SSF55608 1173 1266 6.43E-10 T 30-10-2018 IPR027434 Homing endonuclease CL1_0652 57750cfb47851d1c13e26d48b4f8a974 2019 Pfam PF14551 MCM N-terminal domain 3 76 1.3E-10 T 30-10-2018 IPR027925 MCM N-terminal domain Reactome: R-HSA-176187|Reactome: R-HSA-176974|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962|Reactome: R-HSA-69052 CL1_0652 57750cfb47851d1c13e26d48b4f8a974 2019 SUPERFAMILY SSF50249 5 243 3.94E-62 T 30-10-2018 IPR012340 Nucleic acid-binding, OB-fold CL1_0652 57750cfb47851d1c13e26d48b4f8a974 2019 Pfam PF14890 Intein splicing domain 1423 1749 5.6E-22 T 30-10-2018 CL1_0652 57750cfb47851d1c13e26d48b4f8a974 2019 SUPERFAMILY SSF47413 693 749 7.04E-8 T 30-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 CL1_0652 57750cfb47851d1c13e26d48b4f8a974 2019 Gene3D G3DSA:1.10.260.40 691 757 3.6E-6 T 30-10-2018 CL1_0652 57750cfb47851d1c13e26d48b4f8a974 2019 SUPERFAMILY SSF51294 859 1391 1.65E-33 T 30-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CL1_0652 57750cfb47851d1c13e26d48b4f8a974 2019 Pfam PF14527 WhiA LAGLIDADG-like domain 1181 1262 0.014 T 30-10-2018 IPR039518 WhiA, LAGLIDADG-like domain CL1_0652 57750cfb47851d1c13e26d48b4f8a974 2019 SUPERFAMILY SSF51294 1417 1750 9.42E-32 T 30-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CL1_0652 57750cfb47851d1c13e26d48b4f8a974 2019 Gene3D G3DSA:2.170.16.10 860 991 7.8E-20 T 30-10-2018 CL1_0652 57750cfb47851d1c13e26d48b4f8a974 2019 Pfam PF14890 Intein splicing domain 866 1391 6.7E-30 T 30-10-2018 CL1_0652 57750cfb47851d1c13e26d48b4f8a974 2019 TIGRFAM TIGR01445 intein_Nterm: intein N-terminal splicing region 331 428 1.6E-20 T 30-10-2018 IPR006141 Intein N-terminal splicing region GO:0016539 Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CL1_0652 57750cfb47851d1c13e26d48b4f8a974 2019 TIGRFAM TIGR01445 intein_Nterm: intein N-terminal splicing region 1421 1511 8.5E-15 T 30-10-2018 IPR006141 Intein N-terminal splicing region GO:0016539 Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CL1_0652 57750cfb47851d1c13e26d48b4f8a974 2019 TIGRFAM TIGR01445 intein_Nterm: intein N-terminal splicing region 859 949 6.5E-10 T 30-10-2018 IPR006141 Intein N-terminal splicing region GO:0016539 Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CL1_0652 57750cfb47851d1c13e26d48b4f8a974 2019 SUPERFAMILY SSF55608 487 560 6.8E-6 T 30-10-2018 IPR027434 Homing endonuclease CL1_0652 57750cfb47851d1c13e26d48b4f8a974 2019 Gene3D G3DSA:3.40.50.300 1747 1933 5.6E-69 T 30-10-2018 CL1_0652 57750cfb47851d1c13e26d48b4f8a974 2019 Gene3D G3DSA:3.40.50.300 258 331 4.2E-23 T 30-10-2018 CL1_0652 57750cfb47851d1c13e26d48b4f8a974 2019 Gene3D G3DSA:3.40.50.300 782 859 7.9E-20 T 30-10-2018 CL1_0652 57750cfb47851d1c13e26d48b4f8a974 2019 Gene3D G3DSA:3.40.50.300 1387 1420 3.2E-8 T 30-10-2018 CL1_0825 861917ce6fd504bdfef60e087d0746da 367 PIRSF PIRSF000390 1 367 1.5E-127 T 30-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase CL1_0825 861917ce6fd504bdfef60e087d0746da 367 Gene3D G3DSA:3.40.640.10 1 240 1.0E-105 T 30-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 CL1_0825 861917ce6fd504bdfef60e087d0746da 367 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 11 362 3.9E-136 T 30-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase CL1_0825 861917ce6fd504bdfef60e087d0746da 367 Gene3D G3DSA:3.90.1150.10 241 367 2.4E-40 T 30-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 CL1_0825 861917ce6fd504bdfef60e087d0746da 367 SUPERFAMILY SSF53383 3 365 9.55E-130 T 30-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase CL1_0959 d57f0efdc5544b2ab65860426d838d61 247 SUPERFAMILY SSF56024 97 241 4.04E-32 T 30-10-2018 CL1_0959 d57f0efdc5544b2ab65860426d838d61 247 Pfam PF13091 PLD-like domain 114 242 3.1E-24 T 30-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 CL1_0959 d57f0efdc5544b2ab65860426d838d61 247 SMART SM00155 189 216 1.2E-5 T 30-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 CL1_0959 d57f0efdc5544b2ab65860426d838d61 247 Gene3D G3DSA:3.30.870.10 78 245 4.5E-38 T 30-10-2018 CL1_0533 7ba63e7ff41fe5086ed4a2faa8d038a7 163 Pfam PF13470 PIN domain 5 124 1.8E-11 T 30-10-2018 IPR002716 PIN domain CL1_0533 7ba63e7ff41fe5086ed4a2faa8d038a7 163 TIGRFAM TIGR00305 TIGR00305: putative toxin-antitoxin system toxin component, PIN family 5 124 4.2E-9 T 30-10-2018 IPR002850 PIN family, putative toxin-antitoxin system toxin component CL1_0533 7ba63e7ff41fe5086ed4a2faa8d038a7 163 SUPERFAMILY SSF88723 1 130 1.28E-5 T 30-10-2018 IPR029060 PIN-like domain superfamily CL1_1775 627ace330859fa578b0ae78258c2d053 212 SUPERFAMILY SSF46785 7 95 1.01E-15 T 30-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CL1_1775 627ace330859fa578b0ae78258c2d053 212 Gene3D G3DSA:1.10.10.10 9 92 5.0E-15 T 30-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CL1_1775 627ace330859fa578b0ae78258c2d053 212 Pfam PF12840 Helix-turn-helix domain 16 70 1.3E-10 T 30-10-2018 CL1_1991 8f30bc0a2c51aa071b95288cfb1cfd40 299 Gene3D G3DSA:3.30.2010.10 58 150 3.3E-32 T 30-10-2018 CL1_1991 8f30bc0a2c51aa071b95288cfb1cfd40 299 Pfam PF01435 Peptidase family M48 68 289 2.0E-38 T 30-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 CL1_1991 8f30bc0a2c51aa071b95288cfb1cfd40 299 Hamap MF_00188 Protease HtpX [htpX]. 6 289 27.863 T 30-10-2018 IPR022919 Peptidase M48, protease HtpX, putative GO:0004222 CL1_1503 4db3787e4bbe8ef752a8bede333fae7b 427 Gene3D G3DSA:1.25.40.10 228 410 9.8E-7 T 30-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 CL1_1293 31ccc8b0c6fc21dce813b62289b1ad38 151 TIGRFAM TIGR00240 ATCase_reg: aspartate carbamoyltransferase, regulatory subunit 2 148 1.9E-62 T 30-10-2018 IPR002801 Aspartate transcarbamylase regulatory subunit GO:0006207|GO:0009347 CL1_1293 31ccc8b0c6fc21dce813b62289b1ad38 151 Gene3D G3DSA:3.30.70.140 1 97 1.7E-36 T 30-10-2018 IPR036793 Aspartate carbamoyltransferase regulatory subunit, N-terminal domain superfamily CL1_1293 31ccc8b0c6fc21dce813b62289b1ad38 151 SUPERFAMILY SSF54893 3 98 3.14E-33 T 30-10-2018 IPR036793 Aspartate carbamoyltransferase regulatory subunit, N-terminal domain superfamily CL1_1293 31ccc8b0c6fc21dce813b62289b1ad38 151 ProDom PD006194 REGULATORY ASPARTATE CARBAMOYLTRANSFERASE CHAIN METAL-BINDING ZINC PYRIMIDINE BIOSYNTHESIS SUBUNIT TRANSFERASE 6 97 9.0E-42 T 30-10-2018 IPR020545 Aspartate carbamoyltransferase regulatory subunit, N-terminal CL1_1293 31ccc8b0c6fc21dce813b62289b1ad38 151 Hamap MF_00002 Aspartate carbamoyltransferase regulatory chain [pyrI]. 1 149 34.387 T 30-10-2018 IPR002801 Aspartate transcarbamylase regulatory subunit GO:0006207|GO:0009347 CL1_1293 31ccc8b0c6fc21dce813b62289b1ad38 151 Gene3D G3DSA:2.30.30.20 98 151 9.5E-24 T 30-10-2018 CL1_1293 31ccc8b0c6fc21dce813b62289b1ad38 151 SUPERFAMILY SSF57825 100 148 1.7E-17 T 30-10-2018 IPR036792 Aspartate carbamoyltransferase regulatory subunit, C-terminal domain superfamily CL1_1293 31ccc8b0c6fc21dce813b62289b1ad38 151 Pfam PF01948 Aspartate carbamoyltransferase regulatory chain, allosteric domain 4 95 3.4E-33 T 30-10-2018 IPR020545 Aspartate carbamoyltransferase regulatory subunit, N-terminal CL1_1293 31ccc8b0c6fc21dce813b62289b1ad38 151 Pfam PF02748 Aspartate carbamoyltransferase regulatory chain, metal binding domain 100 147 7.0E-22 T 30-10-2018 IPR020542 Aspartate carbamoyltransferase regulatory subunit, C-terminal CL1_0503 256a24cc46540f216e0ffb7b903c338a 1422 Pfam PF00082 Subtilase family 180 624 1.2E-57 T 30-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CL1_0503 256a24cc46540f216e0ffb7b903c338a 1422 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 377 387 - T 30-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site CL1_0503 256a24cc46540f216e0ffb7b903c338a 1422 PRINTS PR00723 Subtilisin serine protease family (S8) signature 180 199 2.7E-19 T 30-10-2018 IPR015500 Peptidase S8, subtilisin-related CL1_0503 256a24cc46540f216e0ffb7b903c338a 1422 PRINTS PR00723 Subtilisin serine protease family (S8) signature 373 386 2.7E-19 T 30-10-2018 IPR015500 Peptidase S8, subtilisin-related CL1_0503 256a24cc46540f216e0ffb7b903c338a 1422 PRINTS PR00723 Subtilisin serine protease family (S8) signature 571 587 2.7E-19 T 30-10-2018 IPR015500 Peptidase S8, subtilisin-related CL1_0503 256a24cc46540f216e0ffb7b903c338a 1422 SUPERFAMILY SSF52743 90 738 2.67E-63 T 30-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 CL1_0503 256a24cc46540f216e0ffb7b903c338a 1422 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 185 196 - T 30-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site CL1_0503 256a24cc46540f216e0ffb7b903c338a 1422 Gene3D G3DSA:3.40.50.200 172 278 1.1E-6 T 30-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 CL1_0503 256a24cc46540f216e0ffb7b903c338a 1422 Gene3D G3DSA:3.40.50.200 315 641 2.3E-68 T 30-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 CL1_0503 256a24cc46540f216e0ffb7b903c338a 1422 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 572 582 - T 30-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site CL1_0731 e97be207e35ae4c29b0cf06390cc80b2 365 SUPERFAMILY SSF50182 181 245 2.65E-17 T 30-10-2018 IPR010920 LSM domain superfamily CL1_0731 e97be207e35ae4c29b0cf06390cc80b2 365 SUPERFAMILY SSF82861 99 179 1.31E-6 T 30-10-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 CL1_0731 e97be207e35ae4c29b0cf06390cc80b2 365 Gene3D G3DSA:2.30.30.60 196 245 9.0E-14 T 30-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily CL1_0731 e97be207e35ae4c29b0cf06390cc80b2 365 Gene3D G3DSA:3.30.70.100 247 339 2.5E-25 T 30-10-2018 CL1_0731 e97be207e35ae4c29b0cf06390cc80b2 365 Pfam PF00924 Mechanosensitive ion channel 136 335 1.6E-58 T 30-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 CL1_0731 e97be207e35ae4c29b0cf06390cc80b2 365 SUPERFAMILY SSF82689 248 346 4.32E-30 T 30-10-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 CL1_1876 28cb426b59ab323481a76cac604bfe2d 153 Pfam PF06695 Putative small multi-drug export protein 17 143 2.6E-31 T 30-10-2018 IPR009577 Putative small multi-drug export CL1_0554 7f4e994542a3a54020eb3d8f95f53128 76 Gene3D G3DSA:2.40.330.20 1 74 4.6E-5 T 30-10-2018 IPR038619 MraZ superfamily CL1_0554 7f4e994542a3a54020eb3d8f95f53128 76 SUPERFAMILY SSF89447 2 56 3.14E-8 T 30-10-2018 IPR037914 SpoVT-AbrB domain superfamily CL1_0554 7f4e994542a3a54020eb3d8f95f53128 76 SMART SM00966 3 44 2.3E-4 T 30-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 CL1_1086 528e5b7e45327a124282cf8e74a3dea7 438 SUPERFAMILY SSF52210 128 283 3.4E-44 T 30-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CL1_1086 528e5b7e45327a124282cf8e74a3dea7 438 Pfam PF13380 CoA binding domain 9 129 9.4E-17 T 30-10-2018 IPR003781 CoA-binding GO:0048037 CL1_1086 528e5b7e45327a124282cf8e74a3dea7 438 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 146 283 2.2E-57 T 30-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain CL1_1086 528e5b7e45327a124282cf8e74a3dea7 438 Gene3D G3DSA:3.40.50.261 287 437 2.3E-53 T 30-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CL1_1086 528e5b7e45327a124282cf8e74a3dea7 438 Gene3D G3DSA:3.40.50.720 1 125 5.8E-30 T 30-10-2018 CL1_1086 528e5b7e45327a124282cf8e74a3dea7 438 SUPERFAMILY SSF51735 2 126 8.93E-22 T 30-10-2018 IPR036291 NAD(P)-binding domain superfamily CL1_1086 528e5b7e45327a124282cf8e74a3dea7 438 Gene3D G3DSA:3.40.50.261 135 286 5.0E-60 T 30-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CL1_1086 528e5b7e45327a124282cf8e74a3dea7 438 SMART SM00881 4 98 6.1E-19 T 30-10-2018 IPR003781 CoA-binding GO:0048037 CL1_1086 528e5b7e45327a124282cf8e74a3dea7 438 SUPERFAMILY SSF52210 290 436 1.03E-39 T 30-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CL1_1753 e83b00c96ad041a398258e96afc46cf9 886 Gene3D G3DSA:3.40.50.300 2 239 1.4E-34 T 30-10-2018 CL1_1753 e83b00c96ad041a398258e96afc46cf9 886 Gene3D G3DSA:3.40.50.300 672 882 7.0E-37 T 30-10-2018 CL1_1753 e83b00c96ad041a398258e96afc46cf9 886 SUPERFAMILY SSF52540 3 243 2.17E-19 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_1753 e83b00c96ad041a398258e96afc46cf9 886 Gene3D G3DSA:1.10.287.510 386 502 5.7E-12 T 30-10-2018 CL1_1753 e83b00c96ad041a398258e96afc46cf9 886 Pfam PF04423 Rad50 zinc hook motif 417 466 2.2E-7 T 30-10-2018 IPR013134 RAD50, zinc hook Reactome: R-HSA-2559586|Reactome: R-HSA-5685938|Reactome: R-HSA-5685939|Reactome: R-HSA-5685942|Reactome: R-HSA-5693548|Reactome: R-HSA-5693554|Reactome: R-HSA-5693565|Reactome: R-HSA-5693568|Reactome: R-HSA-5693571|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 CL1_1753 e83b00c96ad041a398258e96afc46cf9 886 SUPERFAMILY SSF52540 5 871 8.08E-29 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_1753 e83b00c96ad041a398258e96afc46cf9 886 SUPERFAMILY SSF75712 394 487 9.15E-13 T 30-10-2018 CL1_1753 e83b00c96ad041a398258e96afc46cf9 886 Hamap MF_00449 DNA double-strand break repair Rad50 ATPase [rad50]. 1 880 12.19 T 30-10-2018 IPR022982 DNA double-strand break repair Rad50 ATPase, archaeal type CL1_0017 ce78e522068e8123df07430b9e3bd4be 257 Pfam PF01975 Survival protein SurE 3 193 4.9E-55 T 30-10-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 CL1_0017 ce78e522068e8123df07430b9e3bd4be 257 TIGRFAM TIGR00087 surE: 5'/3'-nucleotidase SurE 1 243 1.7E-71 T 30-10-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 CL1_0017 ce78e522068e8123df07430b9e3bd4be 257 Hamap MF_00060 5'/3'-nucleotidase SurE [surE]. 1 257 33.604 T 30-10-2018 IPR030048 Survival protein SurE GO:0008252 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 CL1_0017 ce78e522068e8123df07430b9e3bd4be 257 Gene3D G3DSA:3.40.1210.10 1 256 1.5E-85 T 30-10-2018 IPR036523 SurE-like phosphatase/nucleotidase superfamily GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 CL1_0017 ce78e522068e8123df07430b9e3bd4be 257 SUPERFAMILY SSF64167 1 254 1.44E-72 T 30-10-2018 CL1_1105 ccadf2206354bbb0de83ebbf2dd5bcb4 162 Pfam PF04008 Adenosine specific kinase 7 160 1.1E-62 T 30-10-2018 IPR007153 Adenosine specific kinase CL1_1105 ccadf2206354bbb0de83ebbf2dd5bcb4 162 SUPERFAMILY SSF103165 2 160 9.42E-61 T 30-10-2018 IPR036902 Ta1353-like superfamily CL1_1105 ccadf2206354bbb0de83ebbf2dd5bcb4 162 Gene3D G3DSA:3.40.1520.10 1 162 4.2E-72 T 30-10-2018 IPR036902 Ta1353-like superfamily CL1_1305 d71df6e0bc5ea299dc22245410eb08c4 239 SUPERFAMILY SSF52540 6 210 3.59E-54 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_1305 d71df6e0bc5ea299dc22245410eb08c4 239 SMART SM00382 26 200 1.5E-13 T 30-10-2018 IPR003593 AAA+ ATPase domain CL1_1305 d71df6e0bc5ea299dc22245410eb08c4 239 Gene3D G3DSA:3.40.50.300 5 236 1.0E-57 T 30-10-2018 CL1_1305 d71df6e0bc5ea299dc22245410eb08c4 239 Pfam PF00005 ABC transporter 18 154 9.0E-24 T 30-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CL1_1276 41e83cc5968f550b4457301335819388 423 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 236 402 1.5E-32 T 30-10-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824 Reactome: R-HSA-196843 CL1_1276 41e83cc5968f550b4457301335819388 423 SUPERFAMILY SSF52402 225 391 3.03E-32 T 30-10-2018 CL1_1276 41e83cc5968f550b4457301335819388 423 Gene3D G3DSA:3.40.50.620 217 407 4.3E-34 T 30-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CL1_0887 bdf3a629034ac0b739e426e95e7f18f4 416 SUPERFAMILY SSF161098 184 415 3.14E-52 T 30-10-2018 IPR035906 MetI-like superfamily CL1_0887 bdf3a629034ac0b739e426e95e7f18f4 416 SUPERFAMILY SSF161098 9 68 9.16E-6 T 30-10-2018 IPR035906 MetI-like superfamily CL1_0887 bdf3a629034ac0b739e426e95e7f18f4 416 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 243 407 3.9E-15 T 30-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 CL1_0887 bdf3a629034ac0b739e426e95e7f18f4 416 Gene3D G3DSA:1.10.3720.10 2 81 2.6E-7 T 30-10-2018 IPR035906 MetI-like superfamily CL1_0887 bdf3a629034ac0b739e426e95e7f18f4 416 Gene3D G3DSA:1.10.3720.10 173 403 1.3E-46 T 30-10-2018 IPR035906 MetI-like superfamily CL1_0653 4e9adb033a019566ba48e68d08624f75 143 SMART SM00653 30 137 1.5E-59 T 30-10-2018 IPR002735 Translation initiation factor IF2/IF5 GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 CL1_0653 4e9adb033a019566ba48e68d08624f75 143 Hamap MF_00232 Translation initiation factor 2 subunit beta [eif2b]. 9 143 33.337 T 30-10-2018 IPR004458 Translation initiation factor 2, beta subunit GO:0003743|GO:0006413 CL1_0653 4e9adb033a019566ba48e68d08624f75 143 Pfam PF01873 Domain found in IF2B/IF5 24 136 1.7E-36 T 30-10-2018 IPR002735 Translation initiation factor IF2/IF5 GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 CL1_0653 4e9adb033a019566ba48e68d08624f75 143 TIGRFAM TIGR00311 aIF-2beta: putative translation initiation factor aIF-2, beta subunit 10 142 2.2E-51 T 30-10-2018 IPR004458 Translation initiation factor 2, beta subunit GO:0003743|GO:0006413 CL1_0653 4e9adb033a019566ba48e68d08624f75 143 SUPERFAMILY SSF100966 9 110 6.15E-28 T 30-10-2018 IPR016189 Translation initiation factor IF2/IF5, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 CL1_0653 4e9adb033a019566ba48e68d08624f75 143 Gene3D G3DSA:3.30.70.3150 41 131 2.9E-31 T 30-10-2018 CL1_0653 4e9adb033a019566ba48e68d08624f75 143 SUPERFAMILY SSF75689 107 142 6.02E-12 T 30-10-2018 IPR016190 Translation initiation factor IF2/IF5, zinc-binding GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 CL1_1696 1674563bbccc343caac034e069171b3c 263 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 30-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CL1_1696 1674563bbccc343caac034e069171b3c 263 Gene3D G3DSA:3.40.50.300 1 245 6.3E-72 T 30-10-2018 CL1_1696 1674563bbccc343caac034e069171b3c 263 Pfam PF00005 ABC transporter 21 162 3.8E-32 T 30-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CL1_1696 1674563bbccc343caac034e069171b3c 263 SUPERFAMILY SSF52540 3 220 1.78E-65 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_1696 1674563bbccc343caac034e069171b3c 263 SMART SM00382 26 210 2.3E-17 T 30-10-2018 IPR003593 AAA+ ATPase domain CL1_1780 ec2c56039ef49dc80c3d4cafa2ffaa85 152 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 10 149 3.0E-27 T 30-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 CL1_1780 ec2c56039ef49dc80c3d4cafa2ffaa85 152 Gene3D G3DSA:3.30.479.10 12 150 1.4E-32 T 30-10-2018 IPR038418 6-pyruvoyl tetrahydropterin synthase/QueD superfamily Reactome: R-HSA-1474151 CL1_1780 ec2c56039ef49dc80c3d4cafa2ffaa85 152 SUPERFAMILY SSF55620 9 150 1.83E-35 T 30-10-2018 CL1_1626 e67c589c0433dfc2350ab1df9f66bf18 503 Pfam PF07831 Pyrimidine nucleoside phosphorylase C-terminal domain 424 486 1.5E-15 T 30-10-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CL1_1626 e67c589c0433dfc2350ab1df9f66bf18 503 Gene3D G3DSA:1.20.970.10 84 151 1.2E-23 T 30-10-2018 CL1_1626 e67c589c0433dfc2350ab1df9f66bf18 503 Pfam PF02885 Glycosyl transferase family, helical bundle domain 89 150 8.0E-15 T 30-10-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 CL1_1626 e67c589c0433dfc2350ab1df9f66bf18 503 PIRSF PIRSF000478 84 502 5.8E-124 T 30-10-2018 IPR000053 Thymidine/pyrimidine-nucleoside phosphorylase GO:0004645|GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CL1_1626 e67c589c0433dfc2350ab1df9f66bf18 503 TIGRFAM TIGR03327 AMP_phos: AMP phosphorylase 3 500 4.6E-245 T 30-10-2018 IPR017713 AMP phosphorylase GO:0009032|GO:0046125 MetaCyc: PWY-5532 CL1_1626 e67c589c0433dfc2350ab1df9f66bf18 503 TIGRFAM TIGR02645 ARCH_P_rylase: putative thymidine phosphorylase 4 494 5.0E-228 T 30-10-2018 IPR013466 Thymidine phosphorylase/AMP phosphorylase GO:0016763 CL1_1626 e67c589c0433dfc2350ab1df9f66bf18 503 ProSitePatterns PS00647 Thymidine and pyrimidine-nucleoside phosphorylases signature. 193 208 - T 30-10-2018 IPR017872 Pyrimidine-nucleoside phosphorylase, conserved site GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CL1_1626 e67c589c0433dfc2350ab1df9f66bf18 503 Hamap MF_02132 AMP phosphorylase. 1 503 46.935 T 30-10-2018 IPR017713 AMP phosphorylase GO:0009032|GO:0046125 MetaCyc: PWY-5532 CL1_1626 e67c589c0433dfc2350ab1df9f66bf18 503 SMART SM00941 424 491 4.3E-26 T 30-10-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CL1_1626 e67c589c0433dfc2350ab1df9f66bf18 503 Gene3D G3DSA:2.40.40.20 1 83 8.7E-38 T 30-10-2018 CL1_1626 e67c589c0433dfc2350ab1df9f66bf18 503 SUPERFAMILY SSF54680 412 495 5.49E-20 T 30-10-2018 IPR036566 Pyrimidine nucleoside phosphorylase-like, C-terminal domain superfamily GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CL1_1626 e67c589c0433dfc2350ab1df9f66bf18 503 Gene3D G3DSA:3.40.1030.10 152 412 3.3E-102 T 30-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 CL1_1626 e67c589c0433dfc2350ab1df9f66bf18 503 SUPERFAMILY SSF47648 86 153 5.63E-16 T 30-10-2018 IPR036320 Glycosyl transferase family 3, N-terminal domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 CL1_1626 e67c589c0433dfc2350ab1df9f66bf18 503 Gene3D G3DSA:3.90.1170.30 413 493 6.2E-30 T 30-10-2018 IPR036566 Pyrimidine nucleoside phosphorylase-like, C-terminal domain superfamily GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CL1_1626 e67c589c0433dfc2350ab1df9f66bf18 503 SUPERFAMILY SSF52418 155 404 7.33E-69 T 30-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 CL1_1626 e67c589c0433dfc2350ab1df9f66bf18 503 Pfam PF00591 Glycosyl transferase family, a/b domain 158 386 3.4E-14 T 30-10-2018 IPR000312 Glycosyl transferase, family 3 GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CL1_0998 6839555eb7b46fa01f73358c697777c7 377 SUPERFAMILY SSF50156 204 293 1.18E-22 T 30-10-2018 IPR036034 PDZ superfamily GO:0005515 CL1_0998 6839555eb7b46fa01f73358c697777c7 377 SMART SM00228 190 263 8.4E-9 T 30-10-2018 IPR001478 PDZ domain GO:0005515 CL1_0998 6839555eb7b46fa01f73358c697777c7 377 Pfam PF02163 Peptidase family M50 115 365 1.4E-21 T 30-10-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 CL1_0998 6839555eb7b46fa01f73358c697777c7 377 Pfam PF13180 PDZ domain 205 272 6.0E-13 T 30-10-2018 IPR001478 PDZ domain GO:0005515 CL1_0998 6839555eb7b46fa01f73358c697777c7 377 PRINTS PR01000 Sterol regulatory element binding protein site 2 protease (M50) signature 123 137 9.7E-24 T 30-10-2018 IPR001193 Membrane-bound transcription factor site-2 protease GO:0004222|GO:0006508|GO:0016020 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 CL1_0998 6839555eb7b46fa01f73358c697777c7 377 PRINTS PR01000 Sterol regulatory element binding protein site 2 protease (M50) signature 155 167 9.7E-24 T 30-10-2018 IPR001193 Membrane-bound transcription factor site-2 protease GO:0004222|GO:0006508|GO:0016020 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 CL1_0998 6839555eb7b46fa01f73358c697777c7 377 PRINTS PR01000 Sterol regulatory element binding protein site 2 protease (M50) signature 139 154 9.7E-24 T 30-10-2018 IPR001193 Membrane-bound transcription factor site-2 protease GO:0004222|GO:0006508|GO:0016020 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 CL1_0998 6839555eb7b46fa01f73358c697777c7 377 PRINTS PR01000 Sterol regulatory element binding protein site 2 protease (M50) signature 103 122 9.7E-24 T 30-10-2018 IPR001193 Membrane-bound transcription factor site-2 protease GO:0004222|GO:0006508|GO:0016020 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 CL1_0998 6839555eb7b46fa01f73358c697777c7 377 Gene3D G3DSA:2.30.42.10 205 282 2.5E-23 T 30-10-2018 CL1_0929 ebe3115dd13aa91f14bd46dd6136714e 460 Gene3D G3DSA:3.40.50.12240 1 456 2.1E-195 T 30-10-2018 CL1_0929 ebe3115dd13aa91f14bd46dd6136714e 460 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 6 72 2.8E-13 T 30-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 CL1_0929 ebe3115dd13aa91f14bd46dd6136714e 460 Hamap MF_00310 V-type ATP synthase beta chain [atpB]. 1 456 61.799 T 30-10-2018 IPR022879 V-type ATP synthase regulatory subunit B/beta Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 CL1_0929 ebe3115dd13aa91f14bd46dd6136714e 460 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 129 347 5.1E-69 T 30-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 CL1_0929 ebe3115dd13aa91f14bd46dd6136714e 460 SUPERFAMILY SSF47917 359 417 1.99E-9 T 30-10-2018 CL1_0929 ebe3115dd13aa91f14bd46dd6136714e 460 TIGRFAM TIGR01041 ATP_syn_B_arch: ATP synthase archaeal, B subunit 2 458 6.4E-267 T 30-10-2018 IPR005724 ATPase, A1 complex, beta subunit GO:0015986|GO:0033178|GO:0046933 CL1_0929 ebe3115dd13aa91f14bd46dd6136714e 460 PIRSF PIRSF039114 1 460 9.4E-256 T 30-10-2018 IPR022879 V-type ATP synthase regulatory subunit B/beta Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 CL1_0929 ebe3115dd13aa91f14bd46dd6136714e 460 SUPERFAMILY SSF52540 76 352 4.43E-89 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_0929 ebe3115dd13aa91f14bd46dd6136714e 460 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 338 347 - T 30-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 CL1_0616 728a1f9efb5ce5d13870f06270b6ba94 121 TIGRFAM TIGR01080 rplX_A_E: ribosomal protein uL24 6 120 4.3E-58 T 30-10-2018 IPR005756 Ribosomal protein L26/L24, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0616 728a1f9efb5ce5d13870f06270b6ba94 121 Hamap MF_01326_A 50S ribosomal protein L24 [rplX]. 5 118 32.127 T 30-10-2018 IPR005756 Ribosomal protein L26/L24, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0616 728a1f9efb5ce5d13870f06270b6ba94 121 Gene3D G3DSA:2.30.30.30 2 121 9.4E-53 T 30-10-2018 IPR014722 Ribosomal protein L2, domain 2 CL1_0616 728a1f9efb5ce5d13870f06270b6ba94 121 Pfam PF16906 Ribosomal proteins L26 eukaryotic, L24P archaeal 5 119 2.6E-35 T 30-10-2018 IPR005756 Ribosomal protein L26/L24, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0616 728a1f9efb5ce5d13870f06270b6ba94 121 SUPERFAMILY SSF50104 6 117 3.83E-39 T 30-10-2018 IPR008991 Translation protein SH3-like domain superfamily CL1_0616 728a1f9efb5ce5d13870f06270b6ba94 121 SMART SM00739 45 72 1.7E-7 T 30-10-2018 IPR005824 KOW CL1_0616 728a1f9efb5ce5d13870f06270b6ba94 121 ProSitePatterns PS01108 Ribosomal protein L24 signature. 49 66 - T 30-10-2018 IPR005825 Ribosomal protein L24/L26, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CL1_0616 728a1f9efb5ce5d13870f06270b6ba94 121 Pfam PF00467 KOW motif 48 79 1.4E-10 T 30-10-2018 IPR005824 KOW CL1_0718 f599cac656ba0550cccdfa6fafd2a672 276 Gene3D G3DSA:1.10.357.140 9 155 1.2E-14 T 30-10-2018 CL1_0718 f599cac656ba0550cccdfa6fafd2a672 276 Hamap MF_01286 Digeranylgeranylglyceryl phosphate synthase. 3 275 22.85 T 30-10-2018 IPR023547 Digeranylgeranylglyceryl phosphate synthase GO:0000287|GO:0005886|GO:0008654|GO:0047295 KEGG: 00564+2.5.1.42|MetaCyc: PWY-6349 CL1_0718 f599cac656ba0550cccdfa6fafd2a672 276 Gene3D G3DSA:1.20.120.1780 156 276 1.3E-5 T 30-10-2018 CL1_0718 f599cac656ba0550cccdfa6fafd2a672 276 Pfam PF01040 UbiA prenyltransferase family 22 256 9.3E-45 T 30-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 CL1_0014 0bfc7243c55db69ae82bfe685dc43aa7 324 PIRSF PIRSF004954 1 319 5.0E-100 T 30-10-2018 IPR005909 Conserved hypothetical protein CHP01210 CL1_0014 0bfc7243c55db69ae82bfe685dc43aa7 324 SUPERFAMILY SSF102114 17 255 1.29E-16 T 30-10-2018 CL1_0014 0bfc7243c55db69ae82bfe685dc43aa7 324 SMART SM00729 17 247 5.4E-26 T 30-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 CL1_0014 0bfc7243c55db69ae82bfe685dc43aa7 324 Pfam PF04055 Radical SAM superfamily 33 179 1.9E-8 T 30-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CL1_0014 0bfc7243c55db69ae82bfe685dc43aa7 324 TIGRFAM TIGR01210 TIGR01210: radical SAM enzyme, TIGR01210 family 3 321 1.1E-122 T 30-10-2018 IPR005909 Conserved hypothetical protein CHP01210 CL1_0179 8634b50daefac8514c2cc4f7ab12fc95 642 PRINTS PR01038 Arginyl-tRNA synthetase signature 330 351 1.8E-23 T 30-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CL1_0179 8634b50daefac8514c2cc4f7ab12fc95 642 PRINTS PR01038 Arginyl-tRNA synthetase signature 125 140 1.8E-23 T 30-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CL1_0179 8634b50daefac8514c2cc4f7ab12fc95 642 PRINTS PR01038 Arginyl-tRNA synthetase signature 164 177 1.8E-23 T 30-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CL1_0179 8634b50daefac8514c2cc4f7ab12fc95 642 PRINTS PR01038 Arginyl-tRNA synthetase signature 140 156 1.8E-23 T 30-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CL1_0179 8634b50daefac8514c2cc4f7ab12fc95 642 SMART SM01016 8 95 4.7E-20 T 30-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CL1_0179 8634b50daefac8514c2cc4f7ab12fc95 642 SUPERFAMILY SSF47323 516 642 2.42E-35 T 30-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CL1_0179 8634b50daefac8514c2cc4f7ab12fc95 642 SMART SM00836 520 642 6.7E-53 T 30-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 CL1_0179 8634b50daefac8514c2cc4f7ab12fc95 642 SUPERFAMILY SSF52374 120 513 1.16E-75 T 30-10-2018 CL1_0179 8634b50daefac8514c2cc4f7ab12fc95 642 Gene3D G3DSA:1.10.730.10 524 642 5.2E-42 T 30-10-2018 CL1_0179 8634b50daefac8514c2cc4f7ab12fc95 642 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 135 144 - T 30-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CL1_0179 8634b50daefac8514c2cc4f7ab12fc95 642 SUPERFAMILY SSF55190 9 116 2.22E-17 T 30-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 CL1_0179 8634b50daefac8514c2cc4f7ab12fc95 642 Gene3D G3DSA:3.30.1360.70 6 121 4.9E-31 T 30-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 CL1_0179 8634b50daefac8514c2cc4f7ab12fc95 642 Gene3D G3DSA:3.40.50.620 122 523 4.6E-156 T 30-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CL1_0179 8634b50daefac8514c2cc4f7ab12fc95 642 Hamap MF_00123 Arginine--tRNA ligase [argS]. 12 642 27.858 T 30-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CL1_0179 8634b50daefac8514c2cc4f7ab12fc95 642 Pfam PF05746 DALR anticodon binding domain 520 642 2.9E-37 T 30-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 CL1_0179 8634b50daefac8514c2cc4f7ab12fc95 642 Pfam PF00750 tRNA synthetases class I (R) 105 360 8.1E-25 T 30-10-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 CL1_0179 8634b50daefac8514c2cc4f7ab12fc95 642 Pfam PF00750 tRNA synthetases class I (R) 390 492 2.1E-10 T 30-10-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 CL1_0179 8634b50daefac8514c2cc4f7ab12fc95 642 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 14 95 8.7E-14 T 30-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CL1_1783 1bb5059f92db0a3069e392d63351e004 155 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 13 106 1.5E-22 T 30-10-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis CL1_1783 1bb5059f92db0a3069e392d63351e004 155 SUPERFAMILY SSF53146 1 112 9.03E-31 T 30-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily CL1_1783 1bb5059f92db0a3069e392d63351e004 155 Gene3D G3DSA:3.30.420.130 1 116 3.6E-31 T 30-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily CL1_0441 a7f823f79fde07d888892d6336199e6c 905 Pfam PF04998 RNA polymerase Rpb1, domain 5 811 876 3.3E-29 T 30-10-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CL1_0441 a7f823f79fde07d888892d6336199e6c 905 Pfam PF04983 RNA polymerase Rpb1, domain 3 490 672 6.9E-38 T 30-10-2018 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CL1_0441 a7f823f79fde07d888892d6336199e6c 905 Pfam PF04997 RNA polymerase Rpb1, domain 1 6 319 8.5E-107 T 30-10-2018 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CL1_0441 a7f823f79fde07d888892d6336199e6c 905 Gene3D G3DSA:2.20.25.410 850 900 5.7E-22 T 30-10-2018 CL1_0441 a7f823f79fde07d888892d6336199e6c 905 SUPERFAMILY SSF64484 4 887 0.0 T 30-10-2018 CL1_0441 a7f823f79fde07d888892d6336199e6c 905 Gene3D G3DSA:1.10.132.30 672 813 2.6E-44 T 30-10-2018 IPR038120 RNA polymerase Rpb1, funnel domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CL1_0441 a7f823f79fde07d888892d6336199e6c 905 Gene3D G3DSA:1.10.274.100 491 671 5.2E-65 T 30-10-2018 CL1_0441 a7f823f79fde07d888892d6336199e6c 905 Gene3D G3DSA:1.20.120.1280 1 122 1.8E-30 T 30-10-2018 CL1_0441 a7f823f79fde07d888892d6336199e6c 905 Gene3D G3DSA:1.20.120.1280 235 284 2.2E-11 T 30-10-2018 CL1_0441 a7f823f79fde07d888892d6336199e6c 905 Gene3D G3DSA:2.40.40.20 311 482 3.0E-80 T 30-10-2018 CL1_0441 a7f823f79fde07d888892d6336199e6c 905 Gene3D G3DSA:3.30.1490.180 354 418 3.0E-80 T 30-10-2018 CL1_0441 a7f823f79fde07d888892d6336199e6c 905 Pfam PF00623 RNA polymerase Rpb1, domain 2 321 487 6.9E-74 T 30-10-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CL1_0441 a7f823f79fde07d888892d6336199e6c 905 SMART SM00663 211 515 5.0E-206 T 30-10-2018 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CL1_0441 a7f823f79fde07d888892d6336199e6c 905 Pfam PF05000 RNA polymerase Rpb1, domain 4 699 804 8.1E-31 T 30-10-2018 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CL1_0441 a7f823f79fde07d888892d6336199e6c 905 TIGRFAM TIGR02390 RNA_pol_rpoA1: DNA-directed RNA polymerase subunit A' 5 894 0.0 T 30-10-2018 IPR012758 DNA-directed RNA polymerase subunit A' (Rpo1N) GO:0003677|GO:0003899|GO:0006351|GO:0008270 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CL1_0122 bf2e1253da5d400eed51d78acb81afc8 459 SUPERFAMILY SSF52540 5 244 5.33E-33 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_0122 bf2e1253da5d400eed51d78acb81afc8 459 Gene3D G3DSA:3.40.50.300 3 170 9.0E-32 T 30-10-2018 CL1_0122 bf2e1253da5d400eed51d78acb81afc8 459 Pfam PF03008 Archaea bacterial proteins of unknown function 309 406 1.9E-30 T 30-10-2018 IPR004256 Domain of unknown function DUF234, DEXX-box ATPase C-terminal CL1_0122 bf2e1253da5d400eed51d78acb81afc8 459 Gene3D G3DSA:1.10.10.10 241 311 1.1E-7 T 30-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CL1_0122 bf2e1253da5d400eed51d78acb81afc8 459 SUPERFAMILY SSF46785 245 318 5.35E-8 T 30-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CL1_0122 bf2e1253da5d400eed51d78acb81afc8 459 Pfam PF01637 ATPase domain predominantly from Archaea 7 201 6.0E-22 T 30-10-2018 IPR011579 ATPase domain GO:0005524 CL1_1385 2bec5aa71858644939ace25ad8f84097 388 SUPERFAMILY SSF81271 309 386 9.94E-19 T 30-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 CL1_1385 2bec5aa71858644939ace25ad8f84097 388 Pfam PF16897 C-terminal region of MMR_HSR1 domain 206 310 5.8E-19 T 30-10-2018 IPR031662 GTP binding protein, second domain CL1_1385 2bec5aa71858644939ace25ad8f84097 388 Gene3D G3DSA:3.10.20.30 312 388 8.2E-29 T 30-10-2018 IPR012675 Beta-grasp domain superfamily CL1_1385 2bec5aa71858644939ace25ad8f84097 388 Gene3D G3DSA:3.40.50.300 72 204 1.2E-33 T 30-10-2018 CL1_1385 2bec5aa71858644939ace25ad8f84097 388 Gene3D G3DSA:3.40.50.300 208 311 3.3E-9 T 30-10-2018 CL1_1385 2bec5aa71858644939ace25ad8f84097 388 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 83 190 2.1E-13 T 30-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CL1_1385 2bec5aa71858644939ace25ad8f84097 388 Pfam PF01926 50S ribosome-binding GTPase 84 184 1.3E-21 T 30-10-2018 IPR006073 GTP binding domain GO:0005525 CL1_1385 2bec5aa71858644939ace25ad8f84097 388 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 85 105 3.4E-28 T 30-10-2018 IPR006073 GTP binding domain GO:0005525 CL1_1385 2bec5aa71858644939ace25ad8f84097 388 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 106 124 3.4E-28 T 30-10-2018 IPR006073 GTP binding domain GO:0005525 CL1_1385 2bec5aa71858644939ace25ad8f84097 388 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 150 168 3.4E-28 T 30-10-2018 IPR006073 GTP binding domain GO:0005525 CL1_1385 2bec5aa71858644939ace25ad8f84097 388 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 133 148 3.4E-28 T 30-10-2018 IPR006073 GTP binding domain GO:0005525 CL1_1385 2bec5aa71858644939ace25ad8f84097 388 SUPERFAMILY SSF52540 84 323 1.07E-51 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_1385 2bec5aa71858644939ace25ad8f84097 388 Pfam PF02824 TGS domain 315 386 4.5E-24 T 30-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 CL1_1337 2e90b9e5961483736a8d9e769336f95b 310 SMART SM00090 68 298 3.0E-84 T 30-10-2018 IPR000687 RIO kinase GO:0004674|GO:0005524 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6791226 CL1_1337 2e90b9e5961483736a8d9e769336f95b 310 Gene3D G3DSA:1.10.10.10 5 94 1.1E-15 T 30-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CL1_1337 2e90b9e5961483736a8d9e769336f95b 310 Gene3D G3DSA:1.10.510.10 203 296 1.6E-18 T 30-10-2018 CL1_1337 2e90b9e5961483736a8d9e769336f95b 310 Pfam PF09202 Rio2, N-terminal 13 92 3.6E-22 T 30-10-2018 IPR015285 RIO2 kinase winged helix domain, N-terminal GO:0004674|GO:0005524|GO:0006468 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6791226 CL1_1337 2e90b9e5961483736a8d9e769336f95b 310 Gene3D G3DSA:3.30.200.20 98 196 8.1E-25 T 30-10-2018 CL1_1337 2e90b9e5961483736a8d9e769336f95b 310 Pfam PF01163 RIO1 family 111 290 2.8E-50 T 30-10-2018 CL1_1337 2e90b9e5961483736a8d9e769336f95b 310 SUPERFAMILY SSF56112 103 273 2.77E-25 T 30-10-2018 IPR011009 Protein kinase-like domain superfamily CL1_1337 2e90b9e5961483736a8d9e769336f95b 310 SUPERFAMILY SSF46785 8 94 1.84E-23 T 30-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CL1_0993 f6bcc6447215db0577c6557ec6838a63 369 Gene3D G3DSA:3.90.550.10 2 242 8.6E-34 T 30-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases CL1_0993 f6bcc6447215db0577c6557ec6838a63 369 SUPERFAMILY SSF53448 4 290 1.53E-38 T 30-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases CL1_0993 f6bcc6447215db0577c6557ec6838a63 369 Pfam PF00535 Glycosyl transferase family 2 6 192 2.0E-19 T 30-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CL1_0342 9fb086e00627be3c0a5ff4db4400f637 500 SUPERFAMILY SSF46785 2 68 8.06E-5 T 30-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CL1_0342 9fb086e00627be3c0a5ff4db4400f637 500 Gene3D G3DSA:1.10.10.2320 61 173 1.5E-13 T 30-10-2018 CL1_0342 9fb086e00627be3c0a5ff4db4400f637 500 Hamap MF_00282 Phenylalanine--tRNA ligase alpha subunit [pheS]. 2 497 37.409 T 30-10-2018 IPR022917 Phenylalanine-tRNA ligase alpha subunit, bacterial/archaeal GO:0004826 KEGG: 00970+6.1.1.20 CL1_0342 9fb086e00627be3c0a5ff4db4400f637 500 Pfam PF01409 tRNA synthetases class II core domain (F) 224 495 2.3E-82 T 30-10-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 CL1_0342 9fb086e00627be3c0a5ff4db4400f637 500 Gene3D G3DSA:1.10.10.2310 23 221 1.5E-13 T 30-10-2018 CL1_0342 9fb086e00627be3c0a5ff4db4400f637 500 Gene3D G3DSA:1.10.10.2330 74 135 1.5E-13 T 30-10-2018 CL1_0342 9fb086e00627be3c0a5ff4db4400f637 500 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 187 497 4.7E-93 T 30-10-2018 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 CL1_0342 9fb086e00627be3c0a5ff4db4400f637 500 Gene3D G3DSA:3.30.930.10 239 500 1.4E-76 T 30-10-2018 CL1_0342 9fb086e00627be3c0a5ff4db4400f637 500 SUPERFAMILY SSF55681 224 497 1.78E-59 T 30-10-2018 CL1_1964 93835a79e99201e752105aad2a3f5ae9 376 Gene3D G3DSA:1.10.8.60 210 291 3.0E-11 T 30-10-2018 CL1_1964 93835a79e99201e752105aad2a3f5ae9 376 SUPERFAMILY SSF52540 22 259 9.26E-29 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_1964 93835a79e99201e752105aad2a3f5ae9 376 Pfam PF13173 AAA domain 38 187 2.0E-8 T 30-10-2018 CL1_1964 93835a79e99201e752105aad2a3f5ae9 376 Gene3D G3DSA:3.40.50.300 5 208 2.2E-27 T 30-10-2018 CL1_1964 93835a79e99201e752105aad2a3f5ae9 376 SUPERFAMILY SSF46785 296 370 3.4E-6 T 30-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CL1_1977 28690ef22afdb9ac203c50259a0fd25b 148 Gene3D G3DSA:2.30.130.90 53 146 7.1E-10 T 30-10-2018 CL1_1977 28690ef22afdb9ac203c50259a0fd25b 148 Pfam PF13636 RNA-binding PUA-like domain of methyltransferase RsmF 96 144 1.9E-13 T 30-10-2018 IPR027391 rRNA small subunit methyltransferase F, RNA-binding PUA-like domain CL1_1811 0e68c38a96cb5d010c8fa2017cd9641c 705 SUPERFAMILY SSF52540 231 536 1.64E-28 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_1811 0e68c38a96cb5d010c8fa2017cd9641c 705 Gene3D G3DSA:3.40.50.300 398 575 1.4E-17 T 30-10-2018 CL1_1811 0e68c38a96cb5d010c8fa2017cd9641c 705 SMART SM00490 446 524 6.0E-9 T 30-10-2018 IPR001650 Helicase, C-terminal CL1_1811 0e68c38a96cb5d010c8fa2017cd9641c 705 Pfam PF00271 Helicase conserved C-terminal domain 428 524 4.7E-6 T 30-10-2018 IPR001650 Helicase, C-terminal CL1_1811 0e68c38a96cb5d010c8fa2017cd9641c 705 SMART SM00487 214 413 1.3E-5 T 30-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CL1_1811 0e68c38a96cb5d010c8fa2017cd9641c 705 SUPERFAMILY SSF109604 4 111 1.44E-8 T 30-10-2018 CL1_1811 0e68c38a96cb5d010c8fa2017cd9641c 705 Gene3D G3DSA:3.40.50.300 209 397 2.3E-10 T 30-10-2018 CL1_1811 0e68c38a96cb5d010c8fa2017cd9641c 705 Pfam PF01966 HD domain 22 115 3.5E-7 T 30-10-2018 IPR006674 HD domain CL1_1811 0e68c38a96cb5d010c8fa2017cd9641c 705 TIGRFAM TIGR01596 cas3_HD: CRISPR-associated endonuclease Cas3-HD 21 188 3.8E-17 T 30-10-2018 IPR006483 CRISPR-associated Cas3-type HD domain CL1_1811 0e68c38a96cb5d010c8fa2017cd9641c 705 Gene3D G3DSA:1.10.3210.30 10 208 1.2E-10 T 30-10-2018 IPR038257 CRISPR-associated Cas3-type HD domain superfamily CL1_1811 0e68c38a96cb5d010c8fa2017cd9641c 705 TIGRFAM TIGR01587 cas3_core: CRISPR-associated helicase Cas3 236 555 7.0E-68 T 30-10-2018 IPR006474 Helicase Cas3, CRISPR-associated, core CL1_2002 feaa6f3ea8b5d1dc9659e9d0f74e0bf0 440 Hamap MF_01892 tRNA(Ile2) 2-agmatinylcytidine synthetase TiaS [tiaS]. 19 438 36.634 T 30-10-2018 IPR024913 tRNA(Ile2) 2-agmatinylcytidine synthetase TiaS GO:0002101|GO:0016879 CL1_2002 feaa6f3ea8b5d1dc9659e9d0f74e0bf0 440 Gene3D G3DSA:3.90.600.20 172 267 3.7E-34 T 30-10-2018 CL1_2002 feaa6f3ea8b5d1dc9659e9d0f74e0bf0 440 Pfam PF01336 OB-fold nucleic acid binding domain 286 357 1.2E-8 T 30-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 CL1_2002 feaa6f3ea8b5d1dc9659e9d0f74e0bf0 440 Gene3D G3DSA:3.30.70.2200 17 171 4.7E-61 T 30-10-2018 CL1_2002 feaa6f3ea8b5d1dc9659e9d0f74e0bf0 440 Pfam PF08489 Domain of unknown function (DUF1743) 156 269 7.7E-38 T 30-10-2018 IPR013696 Domain of unknown function DUF1743 CL1_2002 feaa6f3ea8b5d1dc9659e9d0f74e0bf0 440 Gene3D G3DSA:2.40.50.1010 268 417 8.6E-43 T 30-10-2018 CL1_1368 5ee35f3bc436543881465ed0efe91753 90 Pfam PF04324 BFD-like [2Fe-2S] binding domain 6 58 2.7E-13 T 30-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain CL1_1368 5ee35f3bc436543881465ed0efe91753 90 Gene3D G3DSA:1.10.10.1100 1 67 2.5E-21 T 30-10-2018 CL1_0615 ebcb47b17ecdf28d3da644ceba80f7e5 243 Gene3D G3DSA:2.30.30.30 179 243 5.4E-18 T 30-10-2018 IPR014722 Ribosomal protein L2, domain 2 CL1_0615 ebcb47b17ecdf28d3da644ceba80f7e5 243 Hamap MF_00485 30S ribosomal protein S4e [rps4e]. 8 242 42.773 T 30-10-2018 IPR000876 Ribosomal protein S4e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0615 ebcb47b17ecdf28d3da644ceba80f7e5 243 Gene3D G3DSA:3.10.290.40 1 118 1.4E-49 T 30-10-2018 CL1_0615 ebcb47b17ecdf28d3da644ceba80f7e5 243 Pfam PF08071 RS4NT (NUC023) domain 4 39 7.3E-16 T 30-10-2018 IPR013843 Ribosomal protein S4e, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0615 ebcb47b17ecdf28d3da644ceba80f7e5 243 ProDom PD002667 RIBOSOMAL RIBONUCLEOPROTEIN RNA-BINDING 40S S4 S4 S4E 30S ISOFORM X 88 182 1.0E-41 T 30-10-2018 IPR013845 Ribosomal protein S4e, central region Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0615 ebcb47b17ecdf28d3da644ceba80f7e5 243 ProSitePatterns PS00528 Ribosomal protein S4e signature. 9 23 - T 30-10-2018 IPR018199 Ribosomal protein S4e, N-terminal, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0615 ebcb47b17ecdf28d3da644ceba80f7e5 243 Gene3D G3DSA:2.40.50.740 123 177 6.9E-16 T 30-10-2018 IPR038237 Ribosomal protein S4e, central domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0615 ebcb47b17ecdf28d3da644ceba80f7e5 243 SMART SM00363 44 107 2.8E-9 T 30-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0615 ebcb47b17ecdf28d3da644ceba80f7e5 243 Pfam PF01479 S4 domain 45 91 8.4E-13 T 30-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0615 ebcb47b17ecdf28d3da644ceba80f7e5 243 SUPERFAMILY SSF55174 53 104 1.01E-7 T 30-10-2018 CL1_0615 ebcb47b17ecdf28d3da644ceba80f7e5 243 PIRSF PIRSF002116 2 243 6.4E-100 T 30-10-2018 IPR000876 Ribosomal protein S4e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0615 ebcb47b17ecdf28d3da644ceba80f7e5 243 Pfam PF00900 Ribosomal family S4e 96 173 7.6E-22 T 30-10-2018 IPR013845 Ribosomal protein S4e, central region Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_1911 9878ea5f7329d112f18623cb64f54f7f 273 Pfam PF00950 ABC 3 transport family 4 266 2.8E-27 T 30-10-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 CL1_1911 9878ea5f7329d112f18623cb64f54f7f 273 SUPERFAMILY SSF81345 4 272 3.53E-18 T 30-10-2018 IPR037294 ABC transporter, BtuC-like CL1_0584 2c505c05d65e2d96db44dcd15e154a36 110 Gene3D G3DSA:1.10.10.10 2 108 1.4E-25 T 30-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CL1_0584 2c505c05d65e2d96db44dcd15e154a36 110 SUPERFAMILY SSF46785 3 106 3.96E-23 T 30-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CL1_0584 2c505c05d65e2d96db44dcd15e154a36 110 Pfam PF03551 Transcriptional regulator PadR-like family 21 93 2.9E-18 T 30-10-2018 IPR005149 Transcription regulator PadR, N-terminal CL1_0044 c47f8367683feb4a03b4a791dba550fa 145 SUPERFAMILY SSF63380 1 81 1.45E-17 T 30-10-2018 IPR017938 Riboflavin synthase-like beta-barrel CL1_0044 c47f8367683feb4a03b4a791dba550fa 145 Gene3D G3DSA:2.40.30.20 1 77 1.4E-18 T 30-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 CL1_0044 c47f8367683feb4a03b4a791dba550fa 145 Pfam PF00677 Lumazine binding domain 88 143 1.3E-9 T 30-10-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CL1_0044 c47f8367683feb4a03b4a791dba550fa 145 Pfam PF00677 Lumazine binding domain 3 75 5.8E-14 T 30-10-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CL1_0044 c47f8367683feb4a03b4a791dba550fa 145 SUPERFAMILY SSF63380 81 145 1.53E-14 T 30-10-2018 IPR017938 Riboflavin synthase-like beta-barrel CL1_0044 c47f8367683feb4a03b4a791dba550fa 145 Gene3D G3DSA:2.40.30.20 82 145 1.5E-12 T 30-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 CL1_0703 93cf16735c89d4b953b96d53fdcccb2d 100 SUPERFAMILY SSF89957 2 96 1.7E-30 T 30-10-2018 IPR029756 MTH1187/YkoF-like CL1_0703 93cf16735c89d4b953b96d53fdcccb2d 100 Pfam PF01910 Thiamine-binding protein 4 93 4.8E-32 T 30-10-2018 IPR002767 Thiamine-binding protein CL1_0703 93cf16735c89d4b953b96d53fdcccb2d 100 TIGRFAM TIGR00106 TIGR00106: uncharacterized protein, MTH1187 family 2 97 1.2E-28 T 30-10-2018 IPR002767 Thiamine-binding protein CL1_0703 93cf16735c89d4b953b96d53fdcccb2d 100 Gene3D G3DSA:3.30.70.930 1 97 1.9E-34 T 30-10-2018 IPR029756 MTH1187/YkoF-like CL1_0913 292471295ba4b51e9b1a77a594a2ca3c 335 ProSitePatterns PS00211 ABC transporters family signature. 164 178 - T 30-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CL1_0913 292471295ba4b51e9b1a77a594a2ca3c 335 SMART SM00382 45 249 3.8E-11 T 30-10-2018 IPR003593 AAA+ ATPase domain CL1_0913 292471295ba4b51e9b1a77a594a2ca3c 335 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 243 311 3.0E-20 T 30-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CL1_0913 292471295ba4b51e9b1a77a594a2ca3c 335 Pfam PF00005 ABC transporter 37 191 1.8E-31 T 30-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CL1_0913 292471295ba4b51e9b1a77a594a2ca3c 335 SUPERFAMILY SSF52540 5 263 4.73E-71 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_0913 292471295ba4b51e9b1a77a594a2ca3c 335 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 241 331 1.2E-28 T 30-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CL1_0913 292471295ba4b51e9b1a77a594a2ca3c 335 Gene3D G3DSA:3.40.50.300 3 335 5.8E-97 T 30-10-2018 CL1_0415 b3fe153db92a5328849aeac317b3fe24 237 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 11 76 4.2E-5 T 30-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CL1_0415 b3fe153db92a5328849aeac317b3fe24 237 Gene3D G3DSA:3.40.120.10 3 120 1.1E-5 T 30-10-2018 CL1_0415 b3fe153db92a5328849aeac317b3fe24 237 SUPERFAMILY SSF53738 130 209 1.41E-5 T 30-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CL1_0415 b3fe153db92a5328849aeac317b3fe24 237 SUPERFAMILY SSF53738 10 77 1.1E-6 T 30-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CL1_0797 cb34fa81483e199a8b02345ac8c89985 277 PIRSF PIRSF006250 3 276 1.4E-91 T 30-10-2018 IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD Reactome: R-HSA-196807 CL1_0797 cb34fa81483e199a8b02345ac8c89985 277 Gene3D G3DSA:3.20.20.70 120 263 2.3E-89 T 30-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CL1_0797 cb34fa81483e199a8b02345ac8c89985 277 TIGRFAM TIGR00078 nadC: nicotinate-nucleotide diphosphorylase (carboxylating) 7 273 4.8E-97 T 30-10-2018 IPR004393 Nicotinate-nucleotide pyrophosphorylase GO:0004514|GO:0019363 KEGG: 00760+2.4.2.19|MetaCyc: PWY-5316|MetaCyc: PWY-5653|MetaCyc: PWY-7342|Reactome: R-HSA-196807 CL1_0797 cb34fa81483e199a8b02345ac8c89985 277 SUPERFAMILY SSF51690 104 273 7.06E-49 T 30-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 CL1_0797 cb34fa81483e199a8b02345ac8c89985 277 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 16 102 7.3E-30 T 30-10-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 CL1_0797 cb34fa81483e199a8b02345ac8c89985 277 SUPERFAMILY SSF54675 5 103 1.74E-29 T 30-10-2018 CL1_0797 cb34fa81483e199a8b02345ac8c89985 277 Gene3D G3DSA:3.90.1170.20 9 271 2.3E-89 T 30-10-2018 IPR037128 Quinolinate phosphoribosyl transferase, N-terminal domain superfamily GO:0016763 Reactome: R-HSA-196807 CL1_0797 cb34fa81483e199a8b02345ac8c89985 277 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 104 272 8.6E-50 T 30-10-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 Reactome: R-HSA-196807 CL1_1512 7c260a15ac0d362c5e049b5064aff5f9 345 Gene3D G3DSA:3.40.190.10 121 289 1.0E-126 T 30-10-2018 CL1_1512 7c260a15ac0d362c5e049b5064aff5f9 345 Gene3D G3DSA:3.40.190.10 35 338 1.0E-126 T 30-10-2018 CL1_1512 7c260a15ac0d362c5e049b5064aff5f9 345 TIGRFAM TIGR03730 tungstate_WtpA: tungstate ABC transporter binding protein WtpA 34 307 7.9E-119 T 30-10-2018 IPR022498 Tungstate ABC transporter, substrate-binding protein WtpA GO:1901359 CL1_1512 7c260a15ac0d362c5e049b5064aff5f9 345 SUPERFAMILY SSF53850 32 337 1.34E-49 T 30-10-2018 CL1_1512 7c260a15ac0d362c5e049b5064aff5f9 345 Pfam PF13531 Bacterial extracellular solute-binding protein 35 319 3.7E-35 T 30-10-2018 CL1_2010 c2715c6ac512ba15adb7a97ebd8899fd 396 SUPERFAMILY SSF63882 7 182 3.53E-58 T 30-10-2018 IPR036135 MoeA, N-terminal and linker domain superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CL1_2010 c2715c6ac512ba15adb7a97ebd8899fd 396 Pfam PF03453 MoeA N-terminal region (domain I and II) 9 173 4.7E-47 T 30-10-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CL1_2010 c2715c6ac512ba15adb7a97ebd8899fd 396 Gene3D G3DSA:2.170.190.11 50 148 1.6E-109 T 30-10-2018 CL1_2010 c2715c6ac512ba15adb7a97ebd8899fd 396 Gene3D G3DSA:2.40.340.10 320 396 1.3E-26 T 30-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CL1_2010 c2715c6ac512ba15adb7a97ebd8899fd 396 SUPERFAMILY SSF63867 327 396 4.06E-19 T 30-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CL1_2010 c2715c6ac512ba15adb7a97ebd8899fd 396 SUPERFAMILY SSF53218 181 321 7.07E-35 T 30-10-2018 IPR036425 MoaB/Mog-like domain superfamily CL1_2010 c2715c6ac512ba15adb7a97ebd8899fd 396 Gene3D G3DSA:3.40.980.10 20 314 1.6E-109 T 30-10-2018 IPR036425 MoaB/Mog-like domain superfamily CL1_2010 c2715c6ac512ba15adb7a97ebd8899fd 396 Gene3D G3DSA:3.90.105.10 27 181 1.6E-109 T 30-10-2018 CL1_2010 c2715c6ac512ba15adb7a97ebd8899fd 396 Pfam PF00994 Probable molybdopterin binding domain 186 315 3.4E-18 T 30-10-2018 IPR001453 MoaB/Mog domain CL1_2010 c2715c6ac512ba15adb7a97ebd8899fd 396 Pfam PF03454 MoeA C-terminal region (domain IV) 329 395 1.6E-16 T 30-10-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CL1_2010 c2715c6ac512ba15adb7a97ebd8899fd 396 SMART SM00852 186 317 4.1E-30 T 30-10-2018 IPR001453 MoaB/Mog domain CL1_1822 9d8d0998ac4871a6b065c976c87f5755 207 TIGRFAM TIGR03188 histidine_hisI: phosphoribosyl-ATP diphosphatase 122 202 9.4E-28 T 30-10-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 CL1_1822 9d8d0998ac4871a6b065c976c87f5755 207 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 53 106 2.0E-21 T 30-10-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 CL1_1822 9d8d0998ac4871a6b065c976c87f5755 207 Gene3D G3DSA:1.10.287.1080 118 207 3.2E-26 T 30-10-2018 CL1_1822 9d8d0998ac4871a6b065c976c87f5755 207 SUPERFAMILY SSF141734 2 112 1.7E-43 T 30-10-2018 IPR038019 Phosphoribosyl-AMP cyclohydrolase domain superfamily KEGG: 00340+3.5.4.19 CL1_1822 9d8d0998ac4871a6b065c976c87f5755 207 Hamap MF_01019 Histidine biosynthesis bifunctional protein HisIE [hisI]. 6 207 36.344 T 30-10-2018 IPR023019 Histidine biosynthesis bifunctional protein HisIE GO:0000105|GO:0004635|GO:0004636 KEGG: 00340+3.6.1.31+3.5.4.19 CL1_1822 9d8d0998ac4871a6b065c976c87f5755 207 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 31 103 1.0E-31 T 30-10-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 CL1_1822 9d8d0998ac4871a6b065c976c87f5755 207 Gene3D G3DSA:3.10.20.400 2 94 3.3E-35 T 30-10-2018 IPR038019 Phosphoribosyl-AMP cyclohydrolase domain superfamily KEGG: 00340+3.5.4.19 CL1_1822 9d8d0998ac4871a6b065c976c87f5755 207 Hamap MF_01020 Phosphoribosyl-ATP pyrophosphatase [hisE]. 119 202 18.942 T 30-10-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 CL1_1822 9d8d0998ac4871a6b065c976c87f5755 207 SUPERFAMILY SSF101386 121 206 1.02E-21 T 30-10-2018 CL1_1822 9d8d0998ac4871a6b065c976c87f5755 207 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 122 205 1.2E-13 T 30-10-2018 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 CL1_1822 9d8d0998ac4871a6b065c976c87f5755 207 Hamap MF_01021 Phosphoribosyl-AMP cyclohydrolase [hisI]. 5 107 29.624 T 30-10-2018 IPR026660 Phosphoribosyl-AMP cyclohydrolase GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 CL1_1946 b2d6f84795aa6976ad713965573751bf 330 PIRSF PIRSF005644 2 330 4.0E-91 T 30-10-2018 IPR011854 Carbamoyl dehydratase HypE CL1_1946 b2d6f84795aa6976ad713965573751bf 330 Pfam PF00586 AIR synthase related protein, N-terminal domain 36 140 2.9E-17 T 30-10-2018 IPR016188 PurM-like, N-terminal domain CL1_1946 b2d6f84795aa6976ad713965573751bf 330 Gene3D G3DSA:3.90.650.10 146 330 3.3E-51 T 30-10-2018 IPR036676 PurM-like, C-terminal domain superfamily CL1_1946 b2d6f84795aa6976ad713965573751bf 330 SUPERFAMILY SSF56042 146 322 1.47E-37 T 30-10-2018 IPR036676 PurM-like, C-terminal domain superfamily CL1_1946 b2d6f84795aa6976ad713965573751bf 330 Gene3D G3DSA:3.30.1330.10 3 143 5.2E-29 T 30-10-2018 IPR036921 PurM-like, N-terminal domain superfamily CL1_1946 b2d6f84795aa6976ad713965573751bf 330 SUPERFAMILY SSF55326 5 144 3.29E-27 T 30-10-2018 IPR036921 PurM-like, N-terminal domain superfamily CL1_1946 b2d6f84795aa6976ad713965573751bf 330 Pfam PF02769 AIR synthase related protein, C-terminal domain 152 310 3.1E-27 T 30-10-2018 IPR010918 PurM-like, C-terminal domain CL1_0954 1f29483abe087c84844283c206232946 250 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 6 237 3.7E-58 T 30-10-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 CL1_0954 1f29483abe087c84844283c206232946 250 TIGRFAM TIGR00486 YbgI_SA1388: dinuclear metal center protein, YbgI/SA1388 family 1 248 1.1E-58 T 30-10-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 CL1_0954 1f29483abe087c84844283c206232946 250 Gene3D G3DSA:3.40.1390.30 6 238 2.5E-76 T 30-10-2018 CL1_0954 1f29483abe087c84844283c206232946 250 Gene3D G3DSA:3.40.1390.30 96 221 2.5E-76 T 30-10-2018 CL1_0954 1f29483abe087c84844283c206232946 250 SUPERFAMILY SSF102705 1 245 2.35E-69 T 30-10-2018 IPR036069 GTP cyclohydrolase 1 type 2/Nif3 superfamily CL1_0673 d37626078049ce52e4248cd919306734 152 ProSitePatterns PS00892 HIT domain signature. 81 99 - T 30-10-2018 IPR019808 Histidine triad, conserved site CL1_0673 d37626078049ce52e4248cd919306734 152 Gene3D G3DSA:3.30.428.10 1 139 1.6E-40 T 30-10-2018 IPR036265 HIT-like superfamily CL1_0673 d37626078049ce52e4248cd919306734 152 SUPERFAMILY SSF54197 2 146 3.4E-40 T 30-10-2018 IPR036265 HIT-like superfamily CL1_0673 d37626078049ce52e4248cd919306734 152 Pfam PF01230 HIT domain 10 102 6.0E-25 T 30-10-2018 IPR001310 Histidine triad (HIT) protein CL1_1613 dd533904371a73d88331adaac6f6c901 1188 TIGRFAM TIGR02169 SMC_prok_A: chromosome segregation protein SMC 3 1161 0.0 T 30-10-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 CL1_1613 dd533904371a73d88331adaac6f6c901 1188 Gene3D G3DSA:3.30.70.1620 581 658 5.0E-44 T 30-10-2018 CL1_1613 dd533904371a73d88331adaac6f6c901 1188 ProDom PD936484 POLYPROTEIN GLYCOPROTEIN M G2 TRANSMEMBRANE NONSTRUCTURAL MEMBRANE CONTAINS: PRECURSOR SIGNAL 783 1023 1.0E-4 T 30-10-2018 CL1_1613 dd533904371a73d88331adaac6f6c901 1188 Gene3D G3DSA:1.20.5.340 774 876 1.0E-8 T 30-10-2018 CL1_1613 dd533904371a73d88331adaac6f6c901 1188 PIRSF PIRSF005719 1 1168 4.4E-279 T 30-10-2018 IPR024704 Structural maintenance of chromosomes protein CL1_1613 dd533904371a73d88331adaac6f6c901 1188 Pfam PF02463 RecF/RecN/SMC N terminal domain 3 1154 1.7E-81 T 30-10-2018 IPR003395 RecF/RecN/SMC, N-terminal CL1_1613 dd533904371a73d88331adaac6f6c901 1188 Gene3D G3DSA:3.40.50.300 1010 1181 2.8E-59 T 30-10-2018 CL1_1613 dd533904371a73d88331adaac6f6c901 1188 Pfam PF06470 SMC proteins Flexible Hinge Domain 520 630 5.0E-32 T 30-10-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 CL1_1613 dd533904371a73d88331adaac6f6c901 1188 Hamap MF_01894 Chromosome partition protein Smc [smc]. 2 1163 21.378 T 30-10-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 CL1_1613 dd533904371a73d88331adaac6f6c901 1188 SUPERFAMILY SSF57997 171 349 5.89E-5 T 30-10-2018 CL1_1613 dd533904371a73d88331adaac6f6c901 1188 TIGRFAM TIGR02168 SMC_prok_B: chromosome segregation protein SMC 3 1161 7.4E-235 T 30-10-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 CL1_1613 dd533904371a73d88331adaac6f6c901 1188 SUPERFAMILY SSF57997 379 512 7.85E-7 T 30-10-2018 CL1_1613 dd533904371a73d88331adaac6f6c901 1188 SUPERFAMILY SSF75553 485 677 8.63E-50 T 30-10-2018 IPR036277 SMCs flexible hinge superfamily GO:0005515|GO:0005524|GO:0005694|GO:0051276 CL1_1613 dd533904371a73d88331adaac6f6c901 1188 Gene3D G3DSA:3.40.50.300 2 233 1.2E-60 T 30-10-2018 CL1_1613 dd533904371a73d88331adaac6f6c901 1188 SMART SM00968 520 632 9.3E-43 T 30-10-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 CL1_1613 dd533904371a73d88331adaac6f6c901 1188 SUPERFAMILY SSF52540 1 1168 2.3E-56 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_1613 dd533904371a73d88331adaac6f6c901 1188 Gene3D G3DSA:1.20.1060.20 507 661 5.0E-44 T 30-10-2018 CL1_0725 ae64f0c1924e70eaada44c4b1730e9c8 410 Gene3D G3DSA:2.40.30.10 204 318 1.4E-46 T 30-10-2018 CL1_0725 ae64f0c1924e70eaada44c4b1730e9c8 410 Gene3D G3DSA:2.40.30.10 319 410 8.1E-34 T 30-10-2018 CL1_0725 ae64f0c1924e70eaada44c4b1730e9c8 410 Pfam PF09173 Initiation factor eIF2 gamma, C terminal 324 408 1.9E-30 T 30-10-2018 IPR015256 Translation initiation factor 2, gamma subunit, C-terminal CL1_0725 ae64f0c1924e70eaada44c4b1730e9c8 410 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 10 193 4.1E-17 T 30-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CL1_0725 ae64f0c1924e70eaada44c4b1730e9c8 410 PRINTS PR00315 GTP-binding elongation factor signature 13 26 4.1E-14 T 30-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CL1_0725 ae64f0c1924e70eaada44c4b1730e9c8 410 PRINTS PR00315 GTP-binding elongation factor signature 140 149 4.1E-14 T 30-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CL1_0725 ae64f0c1924e70eaada44c4b1730e9c8 410 PRINTS PR00315 GTP-binding elongation factor signature 103 114 4.1E-14 T 30-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CL1_0725 ae64f0c1924e70eaada44c4b1730e9c8 410 PRINTS PR00315 GTP-binding elongation factor signature 87 97 4.1E-14 T 30-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CL1_0725 ae64f0c1924e70eaada44c4b1730e9c8 410 SUPERFAMILY SSF50465 317 409 3.27E-32 T 30-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal CL1_0725 ae64f0c1924e70eaada44c4b1730e9c8 410 Hamap MF_00119 Translation initiation factor 2 subunit gamma [eif2g]. 4 409 61.137 T 30-10-2018 IPR022424 Translation initiation factor 2, gamma subunit CL1_0725 ae64f0c1924e70eaada44c4b1730e9c8 410 Gene3D G3DSA:3.40.50.300 3 203 5.8E-68 T 30-10-2018 CL1_0725 ae64f0c1924e70eaada44c4b1730e9c8 410 Pfam PF03144 Elongation factor Tu domain 2 231 311 7.1E-11 T 30-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CL1_0725 ae64f0c1924e70eaada44c4b1730e9c8 410 SUPERFAMILY SSF52540 4 209 1.37E-53 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_0725 ae64f0c1924e70eaada44c4b1730e9c8 410 TIGRFAM TIGR03680 eif2g_arch: translation initiation factor 2, gamma subunit 8 409 6.4E-206 T 30-10-2018 IPR022424 Translation initiation factor 2, gamma subunit CL1_0725 ae64f0c1924e70eaada44c4b1730e9c8 410 SUPERFAMILY SSF50447 203 316 1.14E-38 T 30-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily CL1_0725 ae64f0c1924e70eaada44c4b1730e9c8 410 Pfam PF00009 Elongation factor Tu GTP binding domain 12 199 1.1E-35 T 30-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CL1_0597 51ae02447f181577a52e27cbb46bbd3a 334 Gene3D G3DSA:2.30.130.70 23 332 8.3E-148 T 30-10-2018 CL1_0597 51ae02447f181577a52e27cbb46bbd3a 334 Pfam PF01472 PUA domain 251 323 1.1E-20 T 30-10-2018 IPR002478 PUA domain GO:0003723 CL1_0597 51ae02447f181577a52e27cbb46bbd3a 334 TIGRFAM TIGR00425 CBF5: putative rRNA pseudouridine synthase 18 334 1.0E-136 T 30-10-2018 IPR004802 tRNA pseudouridine synthase B family GO:0006396 Reactome: R-HSA-171319|Reactome: R-HSA-6790901 CL1_0597 51ae02447f181577a52e27cbb46bbd3a 334 SUPERFAMILY SSF88697 249 332 2.87E-23 T 30-10-2018 IPR015947 PUA-like superfamily CL1_0597 51ae02447f181577a52e27cbb46bbd3a 334 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 67 119 7.7E-16 T 30-10-2018 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 CL1_0597 51ae02447f181577a52e27cbb46bbd3a 334 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 120 180 1.3E-6 T 30-10-2018 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 CL1_0597 51ae02447f181577a52e27cbb46bbd3a 334 SUPERFAMILY SSF55120 22 247 2.64E-77 T 30-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 CL1_0597 51ae02447f181577a52e27cbb46bbd3a 334 Pfam PF08068 DKCLD (NUC011) domain 15 63 1.5E-18 T 30-10-2018 IPR012960 Dyskerin-like Reactome: R-HSA-171319|Reactome: R-HSA-6790901 CL1_0597 51ae02447f181577a52e27cbb46bbd3a 334 TIGRFAM TIGR00451 unchar_dom_2: uncharacterized domain 2 240 320 1.9E-10 T 30-10-2018 IPR004521 Uncharacterised domain CHP00451 GO:0003723 CL1_0597 51ae02447f181577a52e27cbb46bbd3a 334 SMART SM00359 251 325 5.7E-22 T 30-10-2018 IPR002478 PUA domain GO:0003723 CL1_0597 51ae02447f181577a52e27cbb46bbd3a 334 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 181 247 1.0E-23 T 30-10-2018 IPR032819 tRNA pseudouridylate synthase B, C-terminal Reactome: R-HSA-171319|Reactome: R-HSA-6790901 CL1_0597 51ae02447f181577a52e27cbb46bbd3a 334 SMART SM01136 4 63 1.7E-25 T 30-10-2018 IPR012960 Dyskerin-like Reactome: R-HSA-171319|Reactome: R-HSA-6790901 CL1_0597 51ae02447f181577a52e27cbb46bbd3a 334 Gene3D G3DSA:3.30.2350.10 40 243 8.3E-148 T 30-10-2018 CL1_0597 51ae02447f181577a52e27cbb46bbd3a 334 Hamap MF_01081 Probable tRNA pseudouridine synthase B [truB]. 40 325 51.455 T 30-10-2018 IPR026326 Probable tRNA pseudouridine synthase B, archaeal GO:0006396 CL1_1676 7fff3ac2e54ba808cccb9ea0eb82f478 325 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 11 302 6.6E-121 T 30-10-2018 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 CL1_1676 7fff3ac2e54ba808cccb9ea0eb82f478 325 Pfam PF00005 ABC transporter 20 160 5.4E-34 T 30-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CL1_1676 7fff3ac2e54ba808cccb9ea0eb82f478 325 Gene3D G3DSA:3.40.50.300 1 238 1.4E-73 T 30-10-2018 CL1_1676 7fff3ac2e54ba808cccb9ea0eb82f478 325 SUPERFAMILY SSF52540 3 222 2.19E-69 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_1676 7fff3ac2e54ba808cccb9ea0eb82f478 325 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 30-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CL1_1676 7fff3ac2e54ba808cccb9ea0eb82f478 325 SMART SM00382 28 210 3.5E-9 T 30-10-2018 IPR003593 AAA+ ATPase domain CL1_1676 7fff3ac2e54ba808cccb9ea0eb82f478 325 Pfam PF13732 Domain of unknown function (DUF4162) 215 300 3.4E-9 T 30-10-2018 IPR025302 Domain of unknown function DUF4162 CL1_1434 fd570309dbd65fbc1a8f0bb3caf9182c 82 Pfam PF04066 Multiple resistance and pH regulation protein F (MrpF / PhaF) 25 77 1.8E-15 T 30-10-2018 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 CL1_1360 3664e01ec50c22b2fe3104a09c466606 280 PIRSF PIRSF006816 1 257 5.5E-46 T 30-10-2018 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 CL1_1360 3664e01ec50c22b2fe3104a09c466606 280 SUPERFAMILY SSF63380 1 92 1.15E-15 T 30-10-2018 IPR017938 Riboflavin synthase-like beta-barrel CL1_1360 3664e01ec50c22b2fe3104a09c466606 280 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 215 251 2.4E-12 T 30-10-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain CL1_1360 3664e01ec50c22b2fe3104a09c466606 280 SUPERFAMILY SSF52343 89 250 2.01E-12 T 30-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain CL1_1360 3664e01ec50c22b2fe3104a09c466606 280 Gene3D G3DSA:3.40.50.80 100 205 6.0E-13 T 30-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain CL1_1360 3664e01ec50c22b2fe3104a09c466606 280 Gene3D G3DSA:2.40.30.10 1 92 1.7E-14 T 30-10-2018 CL1_0932 763eff9e1b58334fed03a293f9b3c664 366 SUPERFAMILY SSF103486 35 361 1.57E-77 T 30-10-2018 IPR036079 V-type ATP synthase subunit C-like Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 CL1_0932 763eff9e1b58334fed03a293f9b3c664 366 Gene3D G3DSA:1.10.132.50 35 355 8.2E-61 T 30-10-2018 CL1_0932 763eff9e1b58334fed03a293f9b3c664 366 TIGRFAM TIGR02923 AhaC: ATP synthase A1, C subunit 32 361 5.7E-108 T 30-10-2018 IPR014272 ATPase, V0 complex, c subunit GO:0033179|GO:0046961 CL1_0932 763eff9e1b58334fed03a293f9b3c664 366 Gene3D G3DSA:1.20.1690.10 112 209 8.2E-61 T 30-10-2018 IPR035067 V-type ATPase subunit c Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 CL1_0932 763eff9e1b58334fed03a293f9b3c664 366 Hamap MF_00314 V-type ATP synthase subunit C [atpC]. 31 364 25.069 T 30-10-2018 IPR014272 ATPase, V0 complex, c subunit GO:0033179|GO:0046961 CL1_0932 763eff9e1b58334fed03a293f9b3c664 366 Gene3D G3DSA:1.20.1690.10 220 323 8.2E-61 T 30-10-2018 IPR035067 V-type ATPase subunit c Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 CL1_0932 763eff9e1b58334fed03a293f9b3c664 366 Pfam PF01992 ATP synthase (C/AC39) subunit 39 360 1.4E-66 T 30-10-2018 IPR002843 ATPase, V0 complex, c/d subunit Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 CL1_0045 0bb69ca3e1f9f464fc5a2a22729277d1 360 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 52 93 - T 30-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 CL1_0045 0bb69ca3e1f9f464fc5a2a22729277d1 360 Gene3D G3DSA:3.40.140.10 1 145 3.4E-52 T 30-10-2018 CL1_0045 0bb69ca3e1f9f464fc5a2a22729277d1 360 Pfam PF01872 RibD C-terminal domain 152 344 6.8E-31 T 30-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 CL1_0045 0bb69ca3e1f9f464fc5a2a22729277d1 360 SUPERFAMILY SSF53927 5 149 4.85E-50 T 30-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 CL1_0045 0bb69ca3e1f9f464fc5a2a22729277d1 360 TIGRFAM TIGR00326 eubact_ribD: riboflavin biosynthesis protein RibD 9 346 3.9E-101 T 30-10-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-7991 CL1_0045 0bb69ca3e1f9f464fc5a2a22729277d1 360 SUPERFAMILY SSF53597 152 350 1.57E-43 T 30-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 CL1_0045 0bb69ca3e1f9f464fc5a2a22729277d1 360 Gene3D G3DSA:3.40.430.10 146 353 9.0E-50 T 30-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 CL1_0045 0bb69ca3e1f9f464fc5a2a22729277d1 360 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 4 105 2.6E-25 T 30-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain CL1_0045 0bb69ca3e1f9f464fc5a2a22729277d1 360 PIRSF PIRSF006769 1 353 1.4E-112 T 30-10-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-7991 CL1_1236 ed76b4db489ffa637f1ed486a67b1837 244 PIRSF PIRSF019322 2 244 8.6E-87 T 30-10-2018 IPR016757 Uncharacterised conserved protein UCP019322 CL1_1236 ed76b4db489ffa637f1ed486a67b1837 244 Pfam PF09883 Uncharacterized protein conserved in archaea (DUF2110) 6 235 9.1E-71 T 30-10-2018 IPR016757 Uncharacterised conserved protein UCP019322 CL1_1933 7ab68000aa6c42c86709001700a79379 633 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 9 206 3.2E-70 T 30-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 CL1_1933 7ab68000aa6c42c86709001700a79379 633 Gene3D G3DSA:1.10.599.10 239 622 2.6E-130 T 30-10-2018 IPR013985 Aldehyde ferredoxin oxidoreductase, domain 3 GO:0016625|GO:0051536|GO:0055114 KEGG: 00030+1.2.7.5 CL1_1933 7ab68000aa6c42c86709001700a79379 633 Gene3D G3DSA:1.10.569.10 241 444 2.6E-130 T 30-10-2018 IPR013984 Aldehyde ferredoxin oxidoreductase, domain 2 CL1_1933 7ab68000aa6c42c86709001700a79379 633 SUPERFAMILY SSF48310 214 629 2.49E-117 T 30-10-2018 IPR036021 Aldehyde ferredoxin oxidoreductase-like, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 CL1_1933 7ab68000aa6c42c86709001700a79379 633 Gene3D G3DSA:3.60.9.10 5 211 5.2E-75 T 30-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily CL1_1933 7ab68000aa6c42c86709001700a79379 633 SMART SM00790 7 207 2.8E-109 T 30-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 CL1_1933 7ab68000aa6c42c86709001700a79379 633 SUPERFAMILY SSF56228 6 209 1.57E-65 T 30-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily CL1_1933 7ab68000aa6c42c86709001700a79379 633 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 220 622 4.4E-125 T 30-10-2018 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 CL1_1450 6a1ea747419a4ffdd307cc6255425d60 326 Pfam PF00005 ABC transporter 31 181 6.9E-33 T 30-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CL1_1450 6a1ea747419a4ffdd307cc6255425d60 326 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 232 300 2.9E-19 T 30-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CL1_1450 6a1ea747419a4ffdd307cc6255425d60 326 SMART SM00382 39 238 3.0E-14 T 30-10-2018 IPR003593 AAA+ ATPase domain CL1_1450 6a1ea747419a4ffdd307cc6255425d60 326 ProSitePatterns PS00211 ABC transporters family signature. 153 167 - T 30-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CL1_1450 6a1ea747419a4ffdd307cc6255425d60 326 Gene3D G3DSA:3.40.50.300 3 326 1.1E-100 T 30-10-2018 CL1_1450 6a1ea747419a4ffdd307cc6255425d60 326 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 230 322 2.1E-27 T 30-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CL1_1450 6a1ea747419a4ffdd307cc6255425d60 326 SUPERFAMILY SSF52540 5 251 9.32E-76 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_1362 ef2b37653a154f4ba3050b6d11ecdaa6 243 SMART SM00530 26 81 2.1E-12 T 30-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CL1_1362 ef2b37653a154f4ba3050b6d11ecdaa6 243 PIRSF PIRSF037724 1 237 5.0E-105 T 30-10-2018 IPR017271 Transcription regulator HTH, MJ1545, predicted CL1_1362 ef2b37653a154f4ba3050b6d11ecdaa6 243 SUPERFAMILY SSF47413 22 75 4.1E-12 T 30-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 CL1_1362 ef2b37653a154f4ba3050b6d11ecdaa6 243 Pfam PF01381 Helix-turn-helix 28 75 4.1E-9 T 30-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CL1_1362 ef2b37653a154f4ba3050b6d11ecdaa6 243 Gene3D G3DSA:1.10.260.40 22 89 6.1E-11 T 30-10-2018 CL1_0487 7f54f739e0a4af5a01089847f8a639d0 772 Gene3D G3DSA:3.30.110.120 252 371 2.2E-144 T 30-10-2018 CL1_0487 7f54f739e0a4af5a01089847f8a639d0 772 Pfam PF07503 HypF finger 158 191 4.2E-15 T 30-10-2018 IPR011125 Zinc finger, HypF-type GO:0008270 CL1_0487 7f54f739e0a4af5a01089847f8a639d0 772 Pfam PF07503 HypF finger 108 141 1.5E-16 T 30-10-2018 IPR011125 Zinc finger, HypF-type GO:0008270 CL1_0487 7f54f739e0a4af5a01089847f8a639d0 772 SUPERFAMILY SSF55821 175 390 3.36E-44 T 30-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily CL1_0487 7f54f739e0a4af5a01089847f8a639d0 772 Pfam PF00708 Acylphosphatase 4 87 3.0E-24 T 30-10-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 CL1_0487 7f54f739e0a4af5a01089847f8a639d0 772 Gene3D G3DSA:3.90.870.50 6 362 2.2E-144 T 30-10-2018 CL1_0487 7f54f739e0a4af5a01089847f8a639d0 772 Pfam PF01300 Telomere recombination 208 383 5.5E-46 T 30-10-2018 IPR006070 YrdC-like domain GO:0003725 CL1_0487 7f54f739e0a4af5a01089847f8a639d0 772 Pfam PF00814 Glycoprotease family 610 741 1.3E-8 T 30-10-2018 IPR000905 Gcp-like domain CL1_0487 7f54f739e0a4af5a01089847f8a639d0 772 Gene3D G3DSA:3.30.420.360 383 755 4.2E-103 T 30-10-2018 CL1_0487 7f54f739e0a4af5a01089847f8a639d0 772 PIRSF PIRSF006256 1 764 3.3E-283 T 30-10-2018 IPR004421 Carbamoyltransferase, HypF-type GO:0016743|GO:0046872|GO:0046944 CL1_0487 7f54f739e0a4af5a01089847f8a639d0 772 TIGRFAM TIGR00143 hypF: carbamoyltransferase HypF 7 755 4.7E-262 T 30-10-2018 IPR004421 Carbamoyltransferase, HypF-type GO:0016743|GO:0046872|GO:0046944 CL1_0487 7f54f739e0a4af5a01089847f8a639d0 772 Gene3D G3DSA:3.30.420.350 486 743 4.2E-103 T 30-10-2018 CL1_0487 7f54f739e0a4af5a01089847f8a639d0 772 SUPERFAMILY SSF53067 400 738 3.88E-7 T 30-10-2018 CL1_0487 7f54f739e0a4af5a01089847f8a639d0 772 SUPERFAMILY SSF54975 1 88 4.58E-26 T 30-10-2018 IPR036046 Acylphosphatase-like domain superfamily KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 CL1_0593 e3f034578565d6a3faaebf4f7b7ecb24 260 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 46 148 2.3E-27 T 30-10-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CL1_0593 e3f034578565d6a3faaebf4f7b7ecb24 260 Gene3D G3DSA:2.170.120.12 40 147 1.8E-95 T 30-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CL1_0593 e3f034578565d6a3faaebf4f7b7ecb24 260 Gene3D G3DSA:3.30.1360.10 7 251 1.8E-95 T 30-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CL1_0593 e3f034578565d6a3faaebf4f7b7ecb24 260 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 16 247 1.4E-18 T 30-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CL1_0593 e3f034578565d6a3faaebf4f7b7ecb24 260 SUPERFAMILY SSF56553 39 149 1.96E-28 T 30-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CL1_0593 e3f034578565d6a3faaebf4f7b7ecb24 260 Gene3D G3DSA:3.30.70.3110 157 218 1.8E-95 T 30-10-2018 CL1_0593 e3f034578565d6a3faaebf4f7b7ecb24 260 SMART SM00662 14 254 1.6E-84 T 30-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CL1_0593 e3f034578565d6a3faaebf4f7b7ecb24 260 ProSitePatterns PS00446 RNA polymerases D / 30 to 40 Kd subunits signature. 28 68 - T 30-10-2018 IPR001514 DNA-directed RNA polymerase, 30-40kDa subunit, conserved site GO:0003677|GO:0003899|GO:0006351 CL1_0593 e3f034578565d6a3faaebf4f7b7ecb24 260 Hamap MF_00320 DNA-directed RNA polymerase subunit D [rpoD]. 3 257 32.666 T 30-10-2018 IPR022842 DNA-directed RNA polymerase subunit D (Rpo3) GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CL1_0593 e3f034578565d6a3faaebf4f7b7ecb24 260 SUPERFAMILY SSF55257 3 257 2.94E-29 T 30-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CL1_0003 633c1fc4bc43729202260f08e9973725 158 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 2 150 9.629 T 30-10-2018 IPR022907 VapC family GO:0004540 CL1_0003 633c1fc4bc43729202260f08e9973725 158 Pfam PF01850 PIN domain 2 144 3.7E-17 T 30-10-2018 IPR002716 PIN domain CL1_0003 633c1fc4bc43729202260f08e9973725 158 SUPERFAMILY SSF88723 2 144 1.37E-15 T 30-10-2018 IPR029060 PIN-like domain superfamily CL1_0003 633c1fc4bc43729202260f08e9973725 158 Gene3D G3DSA:3.40.50.1010 1 149 9.3E-12 T 30-10-2018 CL1_1472 16932624b2d612692abcc0f6a7c22462 210 SMART SM00934 3 203 2.1E-60 T 30-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CL1_1472 16932624b2d612692abcc0f6a7c22462 210 Hamap MF_01200_A Orotidine 5'-phosphate decarboxylase [pyrF]. 4 209 37.715 T 30-10-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CL1_1472 16932624b2d612692abcc0f6a7c22462 210 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 3 202 4.9E-37 T 30-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CL1_1472 16932624b2d612692abcc0f6a7c22462 210 SUPERFAMILY SSF51366 2 208 4.42E-59 T 30-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 CL1_1472 16932624b2d612692abcc0f6a7c22462 210 Gene3D G3DSA:3.20.20.70 1 209 7.0E-65 T 30-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CL1_1472 16932624b2d612692abcc0f6a7c22462 210 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 56 69 - T 30-10-2018 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CL1_1472 16932624b2d612692abcc0f6a7c22462 210 TIGRFAM TIGR01740 pyrF: orotidine 5'-phosphate decarboxylase 4 202 6.1E-49 T 30-10-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CL1_1619 103f1317bf61a9d7861a88391fe94436 388 Pfam PF04473 Transglutaminase-like domain 103 249 1.1E-38 T 30-10-2018 IPR007562 Transglutaminase-like domain CL1_0579 799ef7c1c22a86d597a8753a4c72e88c 238 SUPERFAMILY SSF47413 15 62 7.95E-5 T 30-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 CL1_0579 799ef7c1c22a86d597a8753a4c72e88c 238 Pfam PF00156 Phosphoribosyl transferase domain 96 222 8.3E-13 T 30-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CL1_0579 799ef7c1c22a86d597a8753a4c72e88c 238 Pfam PF01381 Helix-turn-helix 17 62 1.3E-5 T 30-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CL1_0579 799ef7c1c22a86d597a8753a4c72e88c 238 SUPERFAMILY SSF53271 75 237 6.56E-36 T 30-10-2018 IPR029057 Phosphoribosyltransferase-like CL1_0579 799ef7c1c22a86d597a8753a4c72e88c 238 Gene3D G3DSA:3.40.50.2020 64 238 3.3E-41 T 30-10-2018 CL1_1132 9869881a1928b769328983a609a01022 182 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 43 159 5.0E-20 T 30-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CL1_1132 9869881a1928b769328983a609a01022 182 Gene3D G3DSA:3.30.460.80 15 141 7.0E-16 T 30-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CL1_1132 9869881a1928b769328983a609a01022 182 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 97 158 8.0E-26 T 30-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CL1_1132 9869881a1928b769328983a609a01022 182 SUPERFAMILY SSF143243 15 168 3.66E-28 T 30-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CL1_1259 43033a1507e5c302395904de60792f8f 302 Pfam PF02558 Ketopantoate reductase PanE/ApbA 3 146 2.4E-36 T 30-10-2018 IPR013332 Ketopantoate reductase, N-terminal domain CL1_1259 43033a1507e5c302395904de60792f8f 302 SUPERFAMILY SSF48179 172 295 6.46E-29 T 30-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 CL1_1259 43033a1507e5c302395904de60792f8f 302 Gene3D G3DSA:1.10.1040.10 172 296 1.2E-42 T 30-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CL1_1259 43033a1507e5c302395904de60792f8f 302 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 2 296 1.5E-80 T 30-10-2018 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0008677|GO:0015940 KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 CL1_1259 43033a1507e5c302395904de60792f8f 302 SUPERFAMILY SSF51735 1 148 9.85E-21 T 30-10-2018 IPR036291 NAD(P)-binding domain superfamily CL1_1259 43033a1507e5c302395904de60792f8f 302 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 172 295 4.6E-33 T 30-10-2018 IPR013752 Ketopantoate reductase, C-terminal domain CL1_1259 43033a1507e5c302395904de60792f8f 302 Gene3D G3DSA:3.40.50.720 1 171 6.4E-62 T 30-10-2018 CL1_0787 cf881e34633718b582ab851e22e705a0 429 Gene3D G3DSA:3.30.1490.20 129 200 2.7E-32 T 30-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 CL1_0787 cf881e34633718b582ab851e22e705a0 429 Gene3D G3DSA:3.30.470.20 201 429 8.9E-80 T 30-10-2018 CL1_0787 cf881e34633718b582ab851e22e705a0 429 SUPERFAMILY SSF51246 339 410 3.61E-18 T 30-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 CL1_0787 cf881e34633718b582ab851e22e705a0 429 Pfam PF02222 ATP-grasp domain 127 303 2.6E-55 T 30-10-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type CL1_0787 cf881e34633718b582ab851e22e705a0 429 SUPERFAMILY SSF52440 8 115 6.62E-34 T 30-10-2018 IPR016185 Pre-ATP-grasp domain superfamily CL1_0787 cf881e34633718b582ab851e22e705a0 429 Hamap MF_01643 Formate-dependent phosphoribosylglycinamide formyltransferase [purT]. 12 411 48.909 T 30-10-2018 IPR005862 Formate-dependent phosphoribosylglycinamide formyltransferase GO:0000287|GO:0004644|GO:0005524|GO:0009152|GO:0016742 CL1_0787 cf881e34633718b582ab851e22e705a0 429 Gene3D G3DSA:3.40.50.20 1 128 1.5E-56 T 30-10-2018 CL1_0787 cf881e34633718b582ab851e22e705a0 429 TIGRFAM TIGR01142 purT: phosphoribosylglycinamide formyltransferase 2 18 410 1.8E-187 T 30-10-2018 IPR005862 Formate-dependent phosphoribosylglycinamide formyltransferase GO:0000287|GO:0004644|GO:0005524|GO:0009152|GO:0016742 CL1_0787 cf881e34633718b582ab851e22e705a0 429 SUPERFAMILY SSF56059 118 324 1.18E-51 T 30-10-2018 CL1_0921 59393694117c44ea40fb730c622bdd82 348 SUPERFAMILY SSF161098 107 329 5.67E-7 T 30-10-2018 IPR035906 MetI-like superfamily CL1_0921 59393694117c44ea40fb730c622bdd82 348 Gene3D G3DSA:1.10.3720.10 102 347 1.5E-9 T 30-10-2018 IPR035906 MetI-like superfamily CL1_0921 59393694117c44ea40fb730c622bdd82 348 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 126 346 1.0E-15 T 30-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 CL1_1584 a067eb4c07ec5bce56271119232ad4f3 299 SUPERFAMILY SSF47954 113 200 4.25E-27 T 30-10-2018 IPR036915 Cyclin-like superfamily CL1_1584 a067eb4c07ec5bce56271119232ad4f3 299 SUPERFAMILY SSF57783 3 50 3.74E-17 T 30-10-2018 CL1_1584 a067eb4c07ec5bce56271119232ad4f3 299 SUPERFAMILY SSF47954 206 298 2.04E-29 T 30-10-2018 IPR036915 Cyclin-like superfamily CL1_1584 a067eb4c07ec5bce56271119232ad4f3 299 SMART SM00385 114 195 1.3E-11 T 30-10-2018 IPR013763 Cyclin-like CL1_1584 a067eb4c07ec5bce56271119232ad4f3 299 SMART SM00385 210 291 9.5E-13 T 30-10-2018 IPR013763 Cyclin-like CL1_1584 a067eb4c07ec5bce56271119232ad4f3 299 Pfam PF00382 Transcription factor TFIIB repeat 117 186 1.6E-19 T 30-10-2018 IPR013150 Transcription factor TFIIB, cyclin-like domain GO:0017025 CL1_1584 a067eb4c07ec5bce56271119232ad4f3 299 Pfam PF00382 Transcription factor TFIIB repeat 212 282 3.2E-22 T 30-10-2018 IPR013150 Transcription factor TFIIB, cyclin-like domain GO:0017025 CL1_1584 a067eb4c07ec5bce56271119232ad4f3 299 PRINTS PR00685 Transcription initiation factor IIB signature 156 175 1.3E-61 T 30-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 CL1_1584 a067eb4c07ec5bce56271119232ad4f3 299 PRINTS PR00685 Transcription initiation factor IIB signature 182 197 1.3E-61 T 30-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 CL1_1584 a067eb4c07ec5bce56271119232ad4f3 299 PRINTS PR00685 Transcription initiation factor IIB signature 54 75 1.3E-61 T 30-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 CL1_1584 a067eb4c07ec5bce56271119232ad4f3 299 PRINTS PR00685 Transcription initiation factor IIB signature 277 291 1.3E-61 T 30-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 CL1_1584 a067eb4c07ec5bce56271119232ad4f3 299 PRINTS PR00685 Transcription initiation factor IIB signature 19 39 1.3E-61 T 30-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 CL1_1584 a067eb4c07ec5bce56271119232ad4f3 299 PRINTS PR00685 Transcription initiation factor IIB signature 41 54 1.3E-61 T 30-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 CL1_1584 a067eb4c07ec5bce56271119232ad4f3 299 PRINTS PR00685 Transcription initiation factor IIB signature 245 261 1.3E-61 T 30-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 CL1_1584 a067eb4c07ec5bce56271119232ad4f3 299 PRINTS PR00685 Transcription initiation factor IIB signature 211 229 1.3E-61 T 30-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 CL1_1584 a067eb4c07ec5bce56271119232ad4f3 299 Pfam PF08271 TFIIB zinc-binding 6 47 1.4E-18 T 30-10-2018 IPR013137 Zinc finger, TFIIB-type CL1_1584 a067eb4c07ec5bce56271119232ad4f3 299 Gene3D G3DSA:1.10.472.170 6 197 3.4E-67 T 30-10-2018 CL1_1584 a067eb4c07ec5bce56271119232ad4f3 299 Gene3D G3DSA:1.10.472.10 207 299 2.9E-28 T 30-10-2018 CL1_1584 a067eb4c07ec5bce56271119232ad4f3 299 ProSitePatterns PS00782 Transcription factor TFIIB repeat signature. 148 163 - T 30-10-2018 IPR023486 Transcription factor TFIIB, conserved site Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-674695|Reactome: R-HSA-6807505|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-76042 CL1_1584 a067eb4c07ec5bce56271119232ad4f3 299 Hamap MF_00383 Transcription initiation factor IIB [tfb]. 1 297 44.565 T 30-10-2018 IPR023484 Transcription initiation factor TFIIB, archaea CL1_1920 933cc3b2e5b778fd47df975c45f5c1f9 703 Pfam PF07728 AAA domain (dynein-related subfamily) 400 584 6.1E-15 T 30-10-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 CL1_1920 933cc3b2e5b778fd47df975c45f5c1f9 703 SUPERFAMILY SSF52540 385 595 1.71E-15 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_1920 933cc3b2e5b778fd47df975c45f5c1f9 703 SMART SM00382 396 594 1.7E-6 T 30-10-2018 IPR003593 AAA+ ATPase domain CL1_1920 933cc3b2e5b778fd47df975c45f5c1f9 703 SUPERFAMILY SSF82171 27 284 1.06E-7 T 30-10-2018 CL1_0459 813ff5eeb8a055d2546208c4a45624c4 275 SMART SM00316 10 83 2.3E-24 T 30-10-2018 IPR022967 RNA-binding domain, S1 CL1_0459 813ff5eeb8a055d2546208c4a45624c4 275 SUPERFAMILY SSF116742 85 174 7.98E-24 T 30-10-2018 IPR024054 Translation initiation factor 2, alpha subunit, middle domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-381042|Reactome: R-HSA-382556|Reactome: R-HSA-72649|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72731 CL1_0459 813ff5eeb8a055d2546208c4a45624c4 275 Gene3D G3DSA:2.40.50.140 3 85 1.3E-31 T 30-10-2018 CL1_0459 813ff5eeb8a055d2546208c4a45624c4 275 Pfam PF00575 S1 RNA binding domain 9 83 4.1E-14 T 30-10-2018 IPR003029 S1 domain GO:0003676 CL1_0459 813ff5eeb8a055d2546208c4a45624c4 275 Gene3D G3DSA:1.10.150.190 86 171 2.0E-32 T 30-10-2018 IPR024054 Translation initiation factor 2, alpha subunit, middle domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-381042|Reactome: R-HSA-382556|Reactome: R-HSA-72649|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72731 CL1_0459 813ff5eeb8a055d2546208c4a45624c4 275 Pfam PF07541 Eukaryotic translation initiation factor 2 alpha subunit 122 233 4.1E-23 T 30-10-2018 IPR011488 Translation initiation factor 2, alpha subunit GO:0003723|GO:0003743 Reactome: R-HSA-156827|Reactome: R-HSA-381042|Reactome: R-HSA-382556|Reactome: R-HSA-72649|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72731 CL1_0459 813ff5eeb8a055d2546208c4a45624c4 275 Gene3D G3DSA:3.30.70.1130 173 262 1.4E-31 T 30-10-2018 IPR024055 Translation initiation factor 2, alpha subunit, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-381042|Reactome: R-HSA-382556|Reactome: R-HSA-72649|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72731 CL1_0459 813ff5eeb8a055d2546208c4a45624c4 275 SUPERFAMILY SSF110993 176 260 5.23E-21 T 30-10-2018 IPR024055 Translation initiation factor 2, alpha subunit, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-381042|Reactome: R-HSA-382556|Reactome: R-HSA-72649|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72731 CL1_0459 813ff5eeb8a055d2546208c4a45624c4 275 SUPERFAMILY SSF50249 7 87 1.36E-20 T 30-10-2018 IPR012340 Nucleic acid-binding, OB-fold CL1_0459 813ff5eeb8a055d2546208c4a45624c4 275 Hamap MF_00231 Translation initiation factor 2 subunit alpha [eif2a]. 3 263 33.64 T 30-10-2018 IPR022964 Translation initiation factor 2, alpha subunit, archaeal CL1_1697 18f5e58f6a1df246e743fc4d5fdc57b9 172 Pfam PF02632 BioY family 26 167 4.3E-41 T 30-10-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 CL1_1697 18f5e58f6a1df246e743fc4d5fdc57b9 172 PIRSF PIRSF016661 1 171 2.7E-49 T 30-10-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 CL1_1697 18f5e58f6a1df246e743fc4d5fdc57b9 172 Gene3D G3DSA:1.10.1760.20 1 171 3.0E-57 T 30-10-2018 CL1_0302 273d14c0f1032e6837b808b15b3b6e94 133 SUPERFAMILY SSF52980 3 107 2.79E-29 T 30-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CL1_0302 273d14c0f1032e6837b808b15b3b6e94 133 PIRSF PIRSF004985 1 126 8.9E-40 T 30-10-2018 IPR014428 Holliday junction resolvase Hjc, archaeal CL1_0302 273d14c0f1032e6837b808b15b3b6e94 133 Gene3D G3DSA:3.40.1350.10 2 129 1.1E-38 T 30-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 CL1_0302 273d14c0f1032e6837b808b15b3b6e94 133 Pfam PF01870 Archaeal holliday junction resolvase (hjc) 9 94 1.7E-30 T 30-10-2018 IPR002732 Holliday junction resolvase Hjc CL1_0302 273d14c0f1032e6837b808b15b3b6e94 133 Hamap MF_01490 Holliday junction resolvase Hjc [hjc]. 2 125 36.749 T 30-10-2018 IPR014428 Holliday junction resolvase Hjc, archaeal CL1_0302 273d14c0f1032e6837b808b15b3b6e94 133 ProDom PD015874 RESOLVASE HOLLIDAY JUNCTION ARCHAEAL HOLLIDAY-JUNCTION TYPE MJ0497 ORF-C21_024 PF1503 NEQ424 10 126 8.0E-29 T 30-10-2018 IPR014428 Holliday junction resolvase Hjc, archaeal CL1_0239 948f3de0fdf2e3c344ff35b96dc65322 618 Gene3D G3DSA:1.10.599.10 235 597 4.4E-89 T 30-10-2018 IPR013985 Aldehyde ferredoxin oxidoreductase, domain 3 GO:0016625|GO:0051536|GO:0055114 KEGG: 00030+1.2.7.5 CL1_0239 948f3de0fdf2e3c344ff35b96dc65322 618 SUPERFAMILY SSF56228 1 203 2.35E-66 T 30-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily CL1_0239 948f3de0fdf2e3c344ff35b96dc65322 618 SMART SM00790 4 204 3.4E-115 T 30-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 CL1_0239 948f3de0fdf2e3c344ff35b96dc65322 618 Gene3D G3DSA:1.10.569.10 237 428 4.4E-89 T 30-10-2018 IPR013984 Aldehyde ferredoxin oxidoreductase, domain 2 CL1_0239 948f3de0fdf2e3c344ff35b96dc65322 618 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 220 597 2.1E-95 T 30-10-2018 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 CL1_0239 948f3de0fdf2e3c344ff35b96dc65322 618 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 7 200 3.3E-69 T 30-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 CL1_0239 948f3de0fdf2e3c344ff35b96dc65322 618 Gene3D G3DSA:3.60.9.10 1 205 8.8E-73 T 30-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily CL1_0239 948f3de0fdf2e3c344ff35b96dc65322 618 SUPERFAMILY SSF48310 207 601 1.44E-100 T 30-10-2018 IPR036021 Aldehyde ferredoxin oxidoreductase-like, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 CL1_1415 9f781645a0b62c1e73e11a5f9c7e1ab0 648 PIRSF PIRSF006439 5 647 1.3E-261 T 30-10-2018 IPR017721 Indolepyruvate ferredoxin oxidoreductase, alpha subunit GO:0043805|GO:0055114 CL1_1415 9f781645a0b62c1e73e11a5f9c7e1ab0 648 SUPERFAMILY SSF52518 14 243 1.73E-55 T 30-10-2018 IPR029061 Thiamin diphosphate-binding fold CL1_1415 9f781645a0b62c1e73e11a5f9c7e1ab0 648 TIGRFAM TIGR03336 IOR_alpha: indolepyruvate ferredoxin oxidoreductase, alpha subunit 16 640 3.6E-271 T 30-10-2018 IPR017721 Indolepyruvate ferredoxin oxidoreductase, alpha subunit GO:0043805|GO:0055114 CL1_1415 9f781645a0b62c1e73e11a5f9c7e1ab0 648 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 28 207 9.9E-15 T 30-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 CL1_1415 9f781645a0b62c1e73e11a5f9c7e1ab0 648 SUPERFAMILY SSF52922 249 354 1.36E-7 T 30-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 CL1_1415 9f781645a0b62c1e73e11a5f9c7e1ab0 648 Gene3D G3DSA:3.30.70.20 578 642 5.5E-10 T 30-10-2018 CL1_1415 9f781645a0b62c1e73e11a5f9c7e1ab0 648 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 410 564 4.0E-29 T 30-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CL1_1415 9f781645a0b62c1e73e11a5f9c7e1ab0 648 Pfam PF00037 4Fe-4S binding domain 619 640 9.5E-7 T 30-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CL1_1415 9f781645a0b62c1e73e11a5f9c7e1ab0 648 SUPERFAMILY SSF54862 584 640 1.81E-13 T 30-10-2018 CL1_1415 9f781645a0b62c1e73e11a5f9c7e1ab0 648 Gene3D G3DSA:3.40.50.970 7 195 6.1E-53 T 30-10-2018 CL1_1415 9f781645a0b62c1e73e11a5f9c7e1ab0 648 SUPERFAMILY SSF52518 380 602 5.77E-30 T 30-10-2018 IPR029061 Thiamin diphosphate-binding fold CL1_1415 9f781645a0b62c1e73e11a5f9c7e1ab0 648 Gene3D G3DSA:3.40.50.970 389 573 7.5E-23 T 30-10-2018 CL1_1415 9f781645a0b62c1e73e11a5f9c7e1ab0 648 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 625 636 - T 30-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CL1_1618 57db05c3eed6575c6b15bcfd6e428fde 405 Pfam PF00270 DEAD/DEAH box helicase 25 191 3.6E-48 T 30-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CL1_1618 57db05c3eed6575c6b15bcfd6e428fde 405 SMART SM00487 20 223 8.4E-64 T 30-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CL1_1618 57db05c3eed6575c6b15bcfd6e428fde 405 SUPERFAMILY SSF52540 71 354 1.63E-74 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_1618 57db05c3eed6575c6b15bcfd6e428fde 405 Gene3D G3DSA:3.40.50.300 1 207 9.5E-77 T 30-10-2018 CL1_1618 57db05c3eed6575c6b15bcfd6e428fde 405 Pfam PF00271 Helicase conserved C-terminal domain 242 333 3.6E-26 T 30-10-2018 IPR001650 Helicase, C-terminal CL1_1618 57db05c3eed6575c6b15bcfd6e428fde 405 SMART SM00490 252 333 1.3E-32 T 30-10-2018 IPR001650 Helicase, C-terminal CL1_1618 57db05c3eed6575c6b15bcfd6e428fde 405 Gene3D G3DSA:3.40.50.300 212 401 5.0E-52 T 30-10-2018 CL1_1618 57db05c3eed6575c6b15bcfd6e428fde 405 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 149 157 - T 30-10-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site CL1_0410 32690d2277e8040afb72288b080e823b 573 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 99 403 9.6E-85 T 30-10-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0004812|GO:0005524|GO:0043039 CL1_0410 32690d2277e8040afb72288b080e823b 573 Hamap MF_02076 Glutamate--tRNA ligase [gltX]. 7 571 39.763 T 30-10-2018 IPR004526 Glutamyl-tRNA synthetase, archaeal/eukaryotic cytosolic GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 CL1_0410 32690d2277e8040afb72288b080e823b 573 Gene3D G3DSA:2.40.240.10 418 517 4.1E-43 T 30-10-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, N-terminal Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CL1_0410 32690d2277e8040afb72288b080e823b 573 Gene3D G3DSA:3.40.50.620 68 410 1.9E-119 T 30-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CL1_0410 32690d2277e8040afb72288b080e823b 573 Gene3D G3DSA:2.40.240.100 411 572 4.1E-43 T 30-10-2018 CL1_0410 32690d2277e8040afb72288b080e823b 573 PRINTS PR00987 Glutamyl-tRNA synthetase signature 103 115 3.7E-21 T 30-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 CL1_0410 32690d2277e8040afb72288b080e823b 573 PRINTS PR00987 Glutamyl-tRNA synthetase signature 280 290 3.7E-21 T 30-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 CL1_0410 32690d2277e8040afb72288b080e823b 573 PRINTS PR00987 Glutamyl-tRNA synthetase signature 132 145 3.7E-21 T 30-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 CL1_0410 32690d2277e8040afb72288b080e823b 573 PRINTS PR00987 Glutamyl-tRNA synthetase signature 296 304 3.7E-21 T 30-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 CL1_0410 32690d2277e8040afb72288b080e823b 573 PRINTS PR00987 Glutamyl-tRNA synthetase signature 117 128 3.7E-21 T 30-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 CL1_0410 32690d2277e8040afb72288b080e823b 573 TIGRFAM TIGR00463 gltX_arch: glutamate--tRNA ligase 3 573 7.5E-212 T 30-10-2018 IPR004526 Glutamyl-tRNA synthetase, archaeal/eukaryotic cytosolic GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 CL1_0410 32690d2277e8040afb72288b080e823b 573 SUPERFAMILY SSF50715 409 570 6.8E-31 T 30-10-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CL1_0410 32690d2277e8040afb72288b080e823b 573 Pfam PF03950 tRNA synthetases class I (E and Q), anti-codon binding domain 409 559 5.7E-30 T 30-10-2018 IPR020059 Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CL1_0410 32690d2277e8040afb72288b080e823b 573 SUPERFAMILY SSF52374 99 415 1.07E-90 T 30-10-2018 CL1_0807 cb67bd16f74f572494c5aef4957096e2 660 Pfam PF13086 AAA domain 174 424 1.2E-55 T 30-10-2018 CL1_0807 cb67bd16f74f572494c5aef4957096e2 660 SUPERFAMILY SSF52540 170 640 6.82E-65 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_0807 cb67bd16f74f572494c5aef4957096e2 660 TIGRFAM TIGR00376 TIGR00376: putative DNA helicase 19 655 1.1E-250 T 30-10-2018 IPR004483 Helicase SMUBP-2/Hcs1-like GO:0003677|GO:0005524 CL1_0807 cb67bd16f74f572494c5aef4957096e2 660 Gene3D G3DSA:3.40.50.300 452 659 9.8E-60 T 30-10-2018 CL1_0807 cb67bd16f74f572494c5aef4957096e2 660 Pfam PF13087 AAA domain 430 630 5.7E-56 T 30-10-2018 CL1_2025 f5d36420c1b26abfc6b36fa0973d4090 248 SUPERFAMILY SSF53335 1 245 1.94E-48 T 30-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CL1_2025 f5d36420c1b26abfc6b36fa0973d4090 248 Gene3D G3DSA:2.20.25.110 150 209 7.4E-37 T 30-10-2018 CL1_2025 f5d36420c1b26abfc6b36fa0973d4090 248 Gene3D G3DSA:3.40.50.150 1 149 1.6E-49 T 30-10-2018 CL1_2025 f5d36420c1b26abfc6b36fa0973d4090 248 Pfam PF13649 Methyltransferase domain 45 139 3.5E-26 T 30-10-2018 CL1_1706 0fd7097e92efc7940a00c8f834c467c1 810 SUPERFAMILY SSF52540 259 397 1.04E-6 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_1706 0fd7097e92efc7940a00c8f834c467c1 810 Pfam PF08351 Domain of unknown function (DUF1726) 129 221 1.1E-32 T 30-10-2018 IPR013562 tRNA(Met) cytidine acetyltransferase TmcA, N-terminal Reactome: R-HSA-6790901 CL1_1706 0fd7097e92efc7940a00c8f834c467c1 810 Pfam PF05127 Helicase 285 458 2.0E-54 T 30-10-2018 IPR007807 Helicase domain Reactome: R-HSA-6790901 CL1_1706 0fd7097e92efc7940a00c8f834c467c1 810 Gene3D G3DSA:3.40.50.12320 281 448 4.1E-34 T 30-10-2018 CL1_1706 0fd7097e92efc7940a00c8f834c467c1 810 SUPERFAMILY SSF55729 489 644 5.89E-10 T 30-10-2018 IPR016181 Acyl-CoA N-acyltransferase CL1_1706 0fd7097e92efc7940a00c8f834c467c1 810 Gene3D G3DSA:3.40.630.30 457 662 6.2E-54 T 30-10-2018 CL1_1706 0fd7097e92efc7940a00c8f834c467c1 810 Pfam PF13718 GNAT acetyltransferase 2 499 615 4.4E-33 T 30-10-2018 IPR000182 GNAT domain CL1_1706 0fd7097e92efc7940a00c8f834c467c1 810 Gene3D G3DSA:3.40.50.11040 24 253 2.1E-12 T 30-10-2018 CL1_1706 0fd7097e92efc7940a00c8f834c467c1 810 Hamap MF_01886 tRNA(Met) cytidine acetyltransferase TmcA [tmcA]. 39 807 47.639 T 30-10-2018 IPR024914 tRNA(Met) cytidine acetyltransferase TmcA GO:0000049|GO:0002101|GO:0051391|GO:0051392 CL1_0509 2742419b07e8256f4818e8c906ae8707 456 Pfam PF01554 MatE 20 179 2.8E-34 T 30-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CL1_0509 2742419b07e8256f4818e8c906ae8707 456 Pfam PF01554 MatE 257 411 2.0E-24 T 30-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CL1_0509 2742419b07e8256f4818e8c906ae8707 456 TIGRFAM TIGR00797 matE: MATE efflux family protein 20 424 2.5E-73 T 30-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CL1_0509 2742419b07e8256f4818e8c906ae8707 456 PIRSF PIRSF006603 1 456 3.8E-144 T 30-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CL1_1757 536ce36a8d27a0a9d36fbef8d6df4de3 96 Gene3D G3DSA:1.20.120.460 2 96 9.6E-35 T 30-10-2018 IPR038317 Pf1176-like superfamily CL1_1757 536ce36a8d27a0a9d36fbef8d6df4de3 96 Pfam PF11505 Protein of unknown function (DUF3216) 6 93 1.3E-31 T 30-10-2018 IPR023108 Domain of unknown function, DUF3216 CL1_0383 7a4bd1dda3c1b57c02899a1ca1c4058b 85 Hamap MF_01471 CRISPR-associated endoribonuclease Cas2 [cas2]. 1 85 15.3 T 30-10-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 CL1_0383 7a4bd1dda3c1b57c02899a1ca1c4058b 85 Pfam PF09827 CRISPR associated protein Cas2 1 68 1.8E-22 T 30-10-2018 IPR019199 Virulence-associated protein D / CRISPR associated protein Cas2 CL1_0383 7a4bd1dda3c1b57c02899a1ca1c4058b 85 Gene3D G3DSA:3.30.70.240 1 66 2.6E-30 T 30-10-2018 CL1_0383 7a4bd1dda3c1b57c02899a1ca1c4058b 85 TIGRFAM TIGR01573 cas2: CRISPR-associated endonuclease Cas2 1 71 1.3E-12 T 30-10-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 CL1_0383 7a4bd1dda3c1b57c02899a1ca1c4058b 85 SUPERFAMILY SSF143430 1 81 1.83E-25 T 30-10-2018 CL1_1196 cde042b019ad45e6a1e1c4c6324dcb28 300 SUPERFAMILY SSF54211 1 156 6.53E-14 T 30-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CL1_1196 cde042b019ad45e6a1e1c4c6324dcb28 300 Pfam PF00288 GHMP kinases N terminal domain 93 151 4.0E-7 T 30-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 CL1_1196 cde042b019ad45e6a1e1c4c6324dcb28 300 PIRSF PIRSF016896 1 296 3.3E-90 T 30-10-2018 IPR012043 Pantoate kinase KEGG: 00770+2.7.1.169|MetaCyc: PWY-6654 CL1_1196 cde042b019ad45e6a1e1c4c6324dcb28 300 Gene3D G3DSA:3.30.230.10 28 158 4.0E-5 T 30-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CL1_1993 ff742f162a7784dfed35866e2ae5d132 132 Gene3D G3DSA:1.20.120.580 1 132 3.1E-10 T 30-10-2018 IPR037038 Bsu32300-like superfamily CL1_1993 ff742f162a7784dfed35866e2ae5d132 132 SUPERFAMILY SSF81593 6 126 1.53E-5 T 30-10-2018 CL1_1993 ff742f162a7784dfed35866e2ae5d132 132 Pfam PF01934 Protein of unknown function DUF86 4 120 1.8E-22 T 30-10-2018 IPR008201 Protein of unknown function DUF86 CL1_1523 b15a7dff4f0b1ea3da2e8eedf64a25f4 191 Gene3D G3DSA:3.50.30.50 1 189 1.5E-57 T 30-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 CL1_1523 b15a7dff4f0b1ea3da2e8eedf64a25f4 191 SUPERFAMILY SSF102198 2 188 1.7E-55 T 30-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 CL1_1523 b15a7dff4f0b1ea3da2e8eedf64a25f4 191 Pfam PF04199 Putative cyclase 3 134 3.3E-25 T 30-10-2018 IPR007325 Kynurenine formamidase/cyclase-like GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 CL1_0291 8f6e5e4756a76c7ae76d12707654c6fd 419 Gene3D G3DSA:2.160.10.10 225 410 1.5E-58 T 30-10-2018 CL1_0291 8f6e5e4756a76c7ae76d12707654c6fd 419 Pfam PF00483 Nucleotidyl transferase 2 232 4.3E-38 T 30-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 CL1_0291 8f6e5e4756a76c7ae76d12707654c6fd 419 SUPERFAMILY SSF51161 243 409 7.73E-38 T 30-10-2018 IPR011004 Trimeric LpxA-like superfamily CL1_0291 8f6e5e4756a76c7ae76d12707654c6fd 419 TIGRFAM TIGR03992 Arch_glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 2 398 8.5E-153 T 30-10-2018 IPR023915 UDP-GlcNAc diphosphorylase/GlcNAc-1-P N-acetyltransferase, GlmU, archaeal-type GO:0003977|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|MetaCyc: PWY-5514 CL1_0291 8f6e5e4756a76c7ae76d12707654c6fd 419 SUPERFAMILY SSF53448 2 312 5.63E-72 T 30-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases CL1_0291 8f6e5e4756a76c7ae76d12707654c6fd 419 Gene3D G3DSA:3.90.550.10 1 224 2.7E-53 T 30-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases CL1_0291 8f6e5e4756a76c7ae76d12707654c6fd 419 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 365 398 1.7E-6 T 30-10-2018 IPR001451 Hexapeptide repeat CL1_0291 8f6e5e4756a76c7ae76d12707654c6fd 419 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 254 287 6.4E-9 T 30-10-2018 IPR001451 Hexapeptide repeat CL1_1123 b71f7873637fdb135284dec5a8c49e43 330 Gene3D G3DSA:3.50.50.60 136 257 5.4E-115 T 30-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily CL1_1123 b71f7873637fdb135284dec5a8c49e43 330 SUPERFAMILY SSF51905 15 320 8.19E-61 T 30-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily CL1_1123 b71f7873637fdb135284dec5a8c49e43 330 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 18 321 1.9E-123 T 30-10-2018 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00450+1.8.1.9 CL1_1123 b71f7873637fdb135284dec5a8c49e43 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 19 41 4.0E-66 T 30-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CL1_1123 b71f7873637fdb135284dec5a8c49e43 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 285 303 4.0E-66 T 30-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CL1_1123 b71f7873637fdb135284dec5a8c49e43 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 72 82 4.0E-66 T 30-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CL1_1123 b71f7873637fdb135284dec5a8c49e43 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 125 133 4.0E-66 T 30-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CL1_1123 b71f7873637fdb135284dec5a8c49e43 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 213 229 4.0E-66 T 30-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CL1_1123 b71f7873637fdb135284dec5a8c49e43 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 51 66 4.0E-66 T 30-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CL1_1123 b71f7873637fdb135284dec5a8c49e43 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 147 159 4.0E-66 T 30-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CL1_1123 b71f7873637fdb135284dec5a8c49e43 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 162 186 4.0E-66 T 30-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CL1_1123 b71f7873637fdb135284dec5a8c49e43 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 251 272 4.0E-66 T 30-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CL1_1123 b71f7873637fdb135284dec5a8c49e43 330 Gene3D G3DSA:3.50.50.60 18 315 5.4E-115 T 30-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily CL1_1123 b71f7873637fdb135284dec5a8c49e43 330 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 249 265 3.7E-40 T 30-10-2018 CL1_1123 b71f7873637fdb135284dec5a8c49e43 330 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 124 142 3.7E-40 T 30-10-2018 CL1_1123 b71f7873637fdb135284dec5a8c49e43 330 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 20 39 3.7E-40 T 30-10-2018 CL1_1123 b71f7873637fdb135284dec5a8c49e43 330 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 166 184 3.7E-40 T 30-10-2018 CL1_1123 b71f7873637fdb135284dec5a8c49e43 330 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 275 297 3.7E-40 T 30-10-2018 CL1_1123 b71f7873637fdb135284dec5a8c49e43 330 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 154 174 - T 30-10-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 CL1_1123 b71f7873637fdb135284dec5a8c49e43 330 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 19 310 3.4E-60 T 30-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CL1_0304 a6606a1df43714cd81510567c90c629b 264 Pfam PF01255 Putative undecaprenyl diphosphate synthase 41 263 8.4E-84 T 30-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CL1_0304 a6606a1df43714cd81510567c90c629b 264 Gene3D G3DSA:3.40.1180.10 18 264 6.7E-103 T 30-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 CL1_0304 a6606a1df43714cd81510567c90c629b 264 SUPERFAMILY SSF64005 32 259 3.4E-88 T 30-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 CL1_0304 a6606a1df43714cd81510567c90c629b 264 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 34 263 6.0E-87 T 30-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CL1_0304 a6606a1df43714cd81510567c90c629b 264 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 34 264 40.367 T 30-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CL1_0304 a6606a1df43714cd81510567c90c629b 264 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 209 226 - T 30-10-2018 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199|Reactome: R-HSA-4755609 CL1_0084 125a4fd95c17d93e3a18608dbee78384 277 Pfam PF01008 Initiation factor 2 subunit family 68 273 6.2E-48 T 30-10-2018 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 CL1_0084 125a4fd95c17d93e3a18608dbee78384 277 SUPERFAMILY SSF100950 6 274 1.57E-66 T 30-10-2018 IPR037171 NagB/RpiA transferase-like CL1_0084 125a4fd95c17d93e3a18608dbee78384 277 Gene3D G3DSA:3.40.50.10470 98 277 4.9E-62 T 30-10-2018 CL1_0084 125a4fd95c17d93e3a18608dbee78384 277 Gene3D G3DSA:1.20.120.420 3 97 3.4E-32 T 30-10-2018 IPR027363 Methylthioribose-1-phosphate isomerase, N-terminal KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 CL1_1570 90951bdf7753ddb9d08714d94c151392 285 Gene3D G3DSA:3.60.15.10 50 127 4.1E-23 T 30-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like CL1_1570 90951bdf7753ddb9d08714d94c151392 285 SUPERFAMILY SSF56281 14 280 8.94E-42 T 30-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like CL1_1570 90951bdf7753ddb9d08714d94c151392 285 Gene3D G3DSA:3.40.50.10890 128 171 4.1E-23 T 30-10-2018 CL1_1999 d6c49626ac1141957b4c08cac7a56ada 335 Pfam PF01916 Deoxyhypusine synthase 34 331 5.8E-113 T 30-10-2018 IPR002773 Deoxyhypusine synthase GO:0008612 Reactome: R-HSA-204626 CL1_1999 d6c49626ac1141957b4c08cac7a56ada 335 TIGRFAM TIGR00321 dhys: deoxyhypusine synthase 20 334 3.5E-121 T 30-10-2018 IPR002773 Deoxyhypusine synthase GO:0008612 Reactome: R-HSA-204626 CL1_1999 d6c49626ac1141957b4c08cac7a56ada 335 Hamap MF_00153 Probable deoxyhypusine synthase [dys]. 31 334 42.261 T 30-10-2018 IPR022899 Deoxyhypusine synthase, putative, archaeal GO:0034038 CL1_1999 d6c49626ac1141957b4c08cac7a56ada 335 SUPERFAMILY SSF52467 5 334 1.73E-115 T 30-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily CL1_1999 d6c49626ac1141957b4c08cac7a56ada 335 Gene3D G3DSA:3.40.910.10 2 335 1.8E-145 T 30-10-2018 IPR036982 Deoxyhypusine synthase superfamily GO:0008612 Reactome: R-HSA-204626 CL1_0467 5bf2f196a7c795de229d64b8e534be6d 456 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 261 370 9.3E-27 T 30-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CL1_0467 5bf2f196a7c795de229d64b8e534be6d 456 Gene3D G3DSA:3.30.310.50 371 455 1.5E-31 T 30-10-2018 CL1_0467 5bf2f196a7c795de229d64b8e534be6d 456 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 236 251 1.5E-17 T 30-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CL1_0467 5bf2f196a7c795de229d64b8e534be6d 456 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 208 221 1.5E-17 T 30-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CL1_0467 5bf2f196a7c795de229d64b8e534be6d 456 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 174 193 1.5E-17 T 30-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CL1_0467 5bf2f196a7c795de229d64b8e534be6d 456 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 94 108 1.5E-17 T 30-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CL1_0467 5bf2f196a7c795de229d64b8e534be6d 456 TIGRFAM TIGR03990 Arch_GlmM: phosphoglucosamine mutase 3 444 2.4E-179 T 30-10-2018 IPR024086 Phosphoglucosamine mutase, archaeal type GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CL1_0467 5bf2f196a7c795de229d64b8e534be6d 456 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 379 442 3.8E-14 T 30-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CL1_0467 5bf2f196a7c795de229d64b8e534be6d 456 Gene3D G3DSA:3.40.120.10 1 152 4.1E-63 T 30-10-2018 CL1_0467 5bf2f196a7c795de229d64b8e534be6d 456 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 3 137 3.5E-47 T 30-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CL1_0467 5bf2f196a7c795de229d64b8e534be6d 456 SUPERFAMILY SSF53738 155 259 3.37E-30 T 30-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CL1_0467 5bf2f196a7c795de229d64b8e534be6d 456 SUPERFAMILY SSF55957 358 454 1.03E-23 T 30-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CL1_0467 5bf2f196a7c795de229d64b8e534be6d 456 Gene3D G3DSA:3.40.120.10 257 365 5.0E-76 T 30-10-2018 CL1_0467 5bf2f196a7c795de229d64b8e534be6d 456 SUPERFAMILY SSF53738 3 180 1.61E-47 T 30-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CL1_0467 5bf2f196a7c795de229d64b8e534be6d 456 Gene3D G3DSA:3.40.120.10 169 358 5.0E-76 T 30-10-2018 CL1_0467 5bf2f196a7c795de229d64b8e534be6d 456 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 156 256 1.9E-29 T 30-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CL1_0467 5bf2f196a7c795de229d64b8e534be6d 456 SUPERFAMILY SSF53738 261 367 5.1E-26 T 30-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CL1_1663 0b1e867e058f3cb7086487ca12292d3f 177 Pfam PF02568 Thiamine biosynthesis protein (ThiI) 1 170 8.1E-47 T 30-10-2018 IPR020536 Thil, AANH domain GO:0004810 KEGG: 00730+2.8.1.4 CL1_1663 0b1e867e058f3cb7086487ca12292d3f 177 SUPERFAMILY SSF52402 1 137 3.4E-28 T 30-10-2018 CL1_1663 0b1e867e058f3cb7086487ca12292d3f 177 Gene3D G3DSA:3.40.50.620 1 176 4.9E-45 T 30-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CL1_1703 6361c71ff94c54a7c69df882db840e69 632 Pfam PF00326 Prolyl oligopeptidase family 421 631 1.9E-58 T 30-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 CL1_1703 6361c71ff94c54a7c69df882db840e69 632 SUPERFAMILY SSF53474 374 631 1.29E-70 T 30-10-2018 IPR029058 Alpha/Beta hydrolase fold CL1_1703 6361c71ff94c54a7c69df882db840e69 632 Pfam PF07676 WD40-like Beta Propeller Repeat 54 89 1.5E-7 T 30-10-2018 IPR011659 WD40-like Beta Propeller CL1_1703 6361c71ff94c54a7c69df882db840e69 632 Gene3D G3DSA:3.40.50.1820 377 632 4.2E-73 T 30-10-2018 IPR029058 Alpha/Beta hydrolase fold CL1_1703 6361c71ff94c54a7c69df882db840e69 632 Gene3D G3DSA:2.120.10.30 23 143 1.7E-15 T 30-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like CL1_1703 6361c71ff94c54a7c69df882db840e69 632 SUPERFAMILY SSF82171 25 369 2.75E-31 T 30-10-2018 CL1_1703 6361c71ff94c54a7c69df882db840e69 632 Gene3D G3DSA:2.120.10.30 149 332 5.0E-9 T 30-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like CL1_0537 da6276447d6d1b21872c7b122c81ac9d 443 SUPERFAMILY SSF46785 373 440 1.34E-15 T 30-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CL1_0537 da6276447d6d1b21872c7b122c81ac9d 443 SMART SM00418 366 443 3.4E-10 T 30-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CL1_0537 da6276447d6d1b21872c7b122c81ac9d 443 SUPERFAMILY SSF53686 5 358 1.31E-74 T 30-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme CL1_0537 da6276447d6d1b21872c7b122c81ac9d 443 Gene3D G3DSA:1.10.10.10 371 441 1.2E-14 T 30-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CL1_0537 da6276447d6d1b21872c7b122c81ac9d 443 Gene3D G3DSA:3.40.50.1100 96 192 2.1E-98 T 30-10-2018 CL1_0537 da6276447d6d1b21872c7b122c81ac9d 443 Gene3D G3DSA:3.40.50.1100 49 358 2.1E-98 T 30-10-2018 CL1_0537 da6276447d6d1b21872c7b122c81ac9d 443 Pfam PF03551 Transcriptional regulator PadR-like family 377 440 4.7E-10 T 30-10-2018 IPR005149 Transcription regulator PadR, N-terminal CL1_0537 da6276447d6d1b21872c7b122c81ac9d 443 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 62 353 7.7E-62 T 30-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme CL1_1369 abc9a6ce5af54dd13588017f8c71d9a6 388 SUPERFAMILY SSF54373 225 318 6.15E-8 T 30-10-2018 CL1_1369 abc9a6ce5af54dd13588017f8c71d9a6 388 SUPERFAMILY SSF51905 2 380 2.46E-58 T 30-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily CL1_1369 abc9a6ce5af54dd13588017f8c71d9a6 388 Gene3D G3DSA:3.30.9.10 82 317 3.0E-116 T 30-10-2018 CL1_1369 abc9a6ce5af54dd13588017f8c71d9a6 388 Gene3D G3DSA:3.50.50.60 4 359 3.0E-116 T 30-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily CL1_1369 abc9a6ce5af54dd13588017f8c71d9a6 388 Pfam PF01266 FAD dependent oxidoreductase 3 355 2.3E-73 T 30-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CL1_1509 2542dd3315c18faa7a21872d61847d1b 462 Pfam PF01637 ATPase domain predominantly from Archaea 2 203 2.6E-29 T 30-10-2018 IPR011579 ATPase domain GO:0005524 CL1_1509 2542dd3315c18faa7a21872d61847d1b 462 SUPERFAMILY SSF52540 1 242 2.66E-35 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_1509 2542dd3315c18faa7a21872d61847d1b 462 Pfam PF09339 IclR helix-turn-helix domain 243 286 2.2E-5 T 30-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CL1_1509 2542dd3315c18faa7a21872d61847d1b 462 SUPERFAMILY SSF46785 241 319 5.97E-10 T 30-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CL1_1509 2542dd3315c18faa7a21872d61847d1b 462 Pfam PF03008 Archaea bacterial proteins of unknown function 310 409 4.9E-33 T 30-10-2018 IPR004256 Domain of unknown function DUF234, DEXX-box ATPase C-terminal CL1_1509 2542dd3315c18faa7a21872d61847d1b 462 Gene3D G3DSA:3.40.50.300 1 169 1.5E-29 T 30-10-2018 CL1_1985 f0708bf0a5039e22e7aea6832afddfc0 576 Hamap MF_00971 DNA-binding protein MutS2 [mutS2]. 3 573 25.241 T 30-10-2018 IPR012401 DNA-binding protein MutS2, archaea CL1_1985 f0708bf0a5039e22e7aea6832afddfc0 576 PIRSF PIRSF029254 1 575 5.0E-194 T 30-10-2018 IPR012401 DNA-binding protein MutS2, archaea CL1_1985 f0708bf0a5039e22e7aea6832afddfc0 576 Gene3D G3DSA:3.40.50.300 342 523 7.5E-19 T 30-10-2018 CL1_1985 f0708bf0a5039e22e7aea6832afddfc0 576 SUPERFAMILY SSF52540 381 547 8.65E-17 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_1985 f0708bf0a5039e22e7aea6832afddfc0 576 SMART SM00534 386 574 1.2E-20 T 30-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 CL1_1807 dd716dc14f79302a21b497467ce2a935 237 SUPERFAMILY SSF55681 4 181 3.79E-50 T 30-10-2018 CL1_1807 dd716dc14f79302a21b497467ce2a935 237 Gene3D G3DSA:2.30.30.100 190 237 2.5E-13 T 30-10-2018 CL1_1807 dd716dc14f79302a21b497467ce2a935 237 Pfam PF02237 Biotin protein ligase C terminal domain 190 235 9.5E-10 T 30-10-2018 IPR003142 Biotin protein ligase, C-terminal GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CL1_1807 dd716dc14f79302a21b497467ce2a935 237 Pfam PF03099 Biotin/lipoate A/B protein ligase family 17 126 6.7E-19 T 30-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 CL1_1807 dd716dc14f79302a21b497467ce2a935 237 Gene3D G3DSA:3.30.930.10 1 187 3.0E-56 T 30-10-2018 CL1_1807 dd716dc14f79302a21b497467ce2a935 237 SUPERFAMILY SSF50037 190 235 5.04E-8 T 30-10-2018 IPR008988 Transcriptional repressor, C-terminal CL1_1807 dd716dc14f79302a21b497467ce2a935 237 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 9 235 7.3E-58 T 30-10-2018 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CL1_1888 4dd62b245714ae4b3c6763eaf7075279 426 Gene3D G3DSA:1.20.1530.20 12 423 9.4E-17 T 30-10-2018 IPR038770 Sodium/solute symporter superfamily CL1_1888 4dd62b245714ae4b3c6763eaf7075279 426 Pfam PF00999 Sodium/hydrogen exchanger family 20 420 1.8E-44 T 30-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 CL1_1939 9a6e13a2ef6fa37803c773bad4e79f3b 59 SUPERFAMILY SSF47113 6 59 1.5E-6 T 30-10-2018 IPR009072 Histone-fold GO:0046982 CL1_0025 cab83e45b78da8ab77afa294fddf394f 331 Pfam PF01297 Zinc-uptake complex component A periplasmic 33 263 1.3E-29 T 30-10-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 CL1_0025 cab83e45b78da8ab77afa294fddf394f 331 SUPERFAMILY SSF53807 30 293 1.03E-38 T 30-10-2018 CL1_0025 cab83e45b78da8ab77afa294fddf394f 331 Gene3D G3DSA:3.40.50.1980 31 191 2.3E-28 T 30-10-2018 CL1_1348 6cfe9874fb7abcdff373a3480890e019 605 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 220 602 1.5E-142 T 30-10-2018 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 CL1_1348 6cfe9874fb7abcdff373a3480890e019 605 Gene3D G3DSA:1.10.569.10 242 428 6.5E-153 T 30-10-2018 IPR013984 Aldehyde ferredoxin oxidoreductase, domain 2 CL1_1348 6cfe9874fb7abcdff373a3480890e019 605 SUPERFAMILY SSF48310 211 605 9.29E-142 T 30-10-2018 IPR036021 Aldehyde ferredoxin oxidoreductase-like, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 CL1_1348 6cfe9874fb7abcdff373a3480890e019 605 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 6 205 1.6E-85 T 30-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 CL1_1348 6cfe9874fb7abcdff373a3480890e019 605 SMART SM00790 4 207 4.8E-135 T 30-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 CL1_1348 6cfe9874fb7abcdff373a3480890e019 605 SUPERFAMILY SSF56228 1 209 4.45E-82 T 30-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily CL1_1348 6cfe9874fb7abcdff373a3480890e019 605 Gene3D G3DSA:3.60.9.10 1 211 2.1E-97 T 30-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily CL1_1348 6cfe9874fb7abcdff373a3480890e019 605 Gene3D G3DSA:1.10.599.10 240 602 6.5E-153 T 30-10-2018 IPR013985 Aldehyde ferredoxin oxidoreductase, domain 3 GO:0016625|GO:0051536|GO:0055114 KEGG: 00030+1.2.7.5 CL1_0904 fdc0205785e2c4741cba102121dfdf6f 343 TIGRFAM TIGR00335 primase_sml: putative DNA primase, eukaryotic-type, small subunit 12 324 1.1E-58 T 30-10-2018 IPR014052 DNA primase, small subunit, eukaryotic/archaeal GO:0003896|GO:0006269 Reactome: R-HSA-113501|Reactome: R-HSA-174411|Reactome: R-HSA-174430|Reactome: R-HSA-68952|Reactome: R-HSA-68962|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183 CL1_0904 fdc0205785e2c4741cba102121dfdf6f 343 SUPERFAMILY SSF56747 6 338 2.4E-95 T 30-10-2018 CL1_0904 fdc0205785e2c4741cba102121dfdf6f 343 Pfam PF01896 DNA primase small subunit 96 304 1.8E-14 T 30-10-2018 IPR002755 DNA primase, small subunit GO:0003896|GO:0006269 Reactome: R-HSA-113501|Reactome: R-HSA-174411|Reactome: R-HSA-174430|Reactome: R-HSA-68952|Reactome: R-HSA-68962|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183 CL1_0904 fdc0205785e2c4741cba102121dfdf6f 343 Gene3D G3DSA:3.90.920.10 9 324 5.3E-122 T 30-10-2018 CL1_0904 fdc0205785e2c4741cba102121dfdf6f 343 Gene3D G3DSA:1.10.8.160 174 275 5.3E-122 T 30-10-2018 CL1_0904 fdc0205785e2c4741cba102121dfdf6f 343 Hamap MF_00700 DNA primase small subunit PriS [priS]. 11 341 23.383 T 30-10-2018 IPR023639 DNA primase small subunit PriS GO:0003896 CL1_0606 4cf166af3122c7cdb450b3334ea0b559 155 TIGRFAM TIGR01309 uL30_arch: ribosomal protein uL30 4 155 2.4E-63 T 30-10-2018 IPR005997 Ribosomal protein L30, archaeal GO:0003735|GO:0006412|GO:0015934 CL1_0606 4cf166af3122c7cdb450b3334ea0b559 155 Pfam PF00327 Ribosomal protein L30p/L7e 6 54 1.2E-15 T 30-10-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain CL1_0606 4cf166af3122c7cdb450b3334ea0b559 155 Gene3D G3DSA:3.30.1390.20 5 143 2.3E-55 T 30-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily CL1_0606 4cf166af3122c7cdb450b3334ea0b559 155 ProSitePatterns PS00634 Ribosomal protein L30 signature. 22 54 - T 30-10-2018 IPR018038 Ribosomal protein L30, conserved site CL1_0606 4cf166af3122c7cdb450b3334ea0b559 155 SUPERFAMILY SSF55129 5 155 1.44E-49 T 30-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily CL1_0606 4cf166af3122c7cdb450b3334ea0b559 155 Gene3D G3DSA:1.10.15.30 60 114 2.3E-55 T 30-10-2018 IPR023106 Ribosomal protein L30, central domain, archaeal type CL1_0606 4cf166af3122c7cdb450b3334ea0b559 155 Hamap MF_01371_A 50S ribosomal protein L30 [rpmD]. 1 155 82.222 T 30-10-2018 IPR005997 Ribosomal protein L30, archaeal GO:0003735|GO:0006412|GO:0015934 CL1_2019 fe002a349e580666e93e6372618c6551 233 Pfam PF02654 Cobalamin-5-phosphate synthase 5 222 2.4E-39 T 30-10-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 CL1_2019 fe002a349e580666e93e6372618c6551 233 TIGRFAM TIGR00317 cobS: cobalamin 5'-phosphate synthase 2 223 4.8E-47 T 30-10-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 CL1_2019 fe002a349e580666e93e6372618c6551 233 Hamap MF_00719 Adenosylcobinamide-GDP ribazoletransferase [cobS]. 1 233 30.315 T 30-10-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 CL1_1351 383d78459f6fe1bdf4b0f9cd0a1a58d6 351 Pfam PF01861 Protein of unknown function DUF43 106 350 1.4E-121 T 30-10-2018 IPR002723 N(4)-bis(aminopropyl)spermidine synthase, C-terminal CL1_1351 383d78459f6fe1bdf4b0f9cd0a1a58d6 351 Gene3D G3DSA:1.10.10.10 1 83 1.1E-30 T 30-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CL1_1351 383d78459f6fe1bdf4b0f9cd0a1a58d6 351 PIRSF PIRSF005895 1 351 5.4E-159 T 30-10-2018 IPR014435 N(4)-bis(aminopropyl)spermidine synthase GO:0006596|GO:0016765 CL1_1351 383d78459f6fe1bdf4b0f9cd0a1a58d6 351 Gene3D G3DSA:3.40.50.150 101 326 3.3E-87 T 30-10-2018 CL1_1351 383d78459f6fe1bdf4b0f9cd0a1a58d6 351 Hamap MF_01947 N(4)-bis(aminopropyl)spermidine synthase [bpsA]. 15 351 50.823 T 30-10-2018 IPR014435 N(4)-bis(aminopropyl)spermidine synthase GO:0006596|GO:0016765 CL1_1351 383d78459f6fe1bdf4b0f9cd0a1a58d6 351 SUPERFAMILY SSF53335 165 285 1.17E-9 T 30-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CL1_1607 e63d14ea742975a1626cc44e4332b524 186 Pfam PF02545 Maf-like protein 2 174 2.3E-56 T 30-10-2018 IPR003697 Maf-like protein GO:0047429 CL1_1607 e63d14ea742975a1626cc44e4332b524 186 Gene3D G3DSA:3.90.950.10 1 180 8.4E-65 T 30-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like CL1_1607 e63d14ea742975a1626cc44e4332b524 186 TIGRFAM TIGR00172 maf: septum formation protein Maf 2 175 2.8E-48 T 30-10-2018 IPR003697 Maf-like protein GO:0047429 CL1_1607 e63d14ea742975a1626cc44e4332b524 186 Hamap MF_00528 Septum formation protein Maf [maf]. 1 183 31.313 T 30-10-2018 IPR003697 Maf-like protein GO:0047429 CL1_1607 e63d14ea742975a1626cc44e4332b524 186 PIRSF PIRSF006305 1 184 6.6E-57 T 30-10-2018 IPR003697 Maf-like protein GO:0047429 CL1_1607 e63d14ea742975a1626cc44e4332b524 186 SUPERFAMILY SSF52972 1 175 9.16E-57 T 30-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like CL1_0607 ba42f31e95e7eb416a74af86afe2152f 235 Gene3D G3DSA:3.30.230.10 123 214 1.7E-29 T 30-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CL1_0607 ba42f31e95e7eb416a74af86afe2152f 235 TIGRFAM TIGR01020 uS5_euk_arch: ribosomal protein uS5 10 221 6.9E-106 T 30-10-2018 IPR005711 Ribosomal protein S5, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-3214858|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8876725|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0607 ba42f31e95e7eb416a74af86afe2152f 235 Pfam PF03719 Ribosomal protein S5, C-terminal domain 145 210 6.0E-21 T 30-10-2018 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 CL1_0607 ba42f31e95e7eb416a74af86afe2152f 235 Gene3D G3DSA:3.30.160.770 14 122 6.4E-37 T 30-10-2018 CL1_0607 ba42f31e95e7eb416a74af86afe2152f 235 SUPERFAMILY SSF54768 62 125 1.88E-18 T 30-10-2018 CL1_0607 ba42f31e95e7eb416a74af86afe2152f 235 Pfam PF00333 Ribosomal protein S5, N-terminal domain 62 123 2.3E-21 T 30-10-2018 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 CL1_0607 ba42f31e95e7eb416a74af86afe2152f 235 Hamap MF_01307_A 30S ribosomal protein S5 [rpsE]. 8 212 47.749 T 30-10-2018 IPR005711 Ribosomal protein S5, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-3214858|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8876725|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0607 ba42f31e95e7eb416a74af86afe2152f 235 SUPERFAMILY SSF54211 138 210 5.06E-19 T 30-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CL1_0607 ba42f31e95e7eb416a74af86afe2152f 235 ProSitePatterns PS00585 Ribosomal protein S5 signature. 77 109 - T 30-10-2018 IPR018192 Ribosomal protein S5, N-terminal, conserved site CL1_0721 2f4365209f667767379ef591b55a7100 207 Gene3D G3DSA:3.40.50.300 1 186 1.2E-50 T 30-10-2018 CL1_0721 2f4365209f667767379ef591b55a7100 207 SUPERFAMILY SSF52540 2 181 2.17E-30 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_0721 2f4365209f667767379ef591b55a7100 207 Hamap MF_00321 Probable GTP-binding protein EngB [engB]. 1 180 21.097 T 30-10-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 CL1_0721 2f4365209f667767379ef591b55a7100 207 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 2 177 9.2E-12 T 30-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CL1_0721 2f4365209f667767379ef591b55a7100 207 Pfam PF01926 50S ribosome-binding GTPase 2 129 1.5E-17 T 30-10-2018 IPR006073 GTP binding domain GO:0005525 CL1_0099 ab056c77a763ddccd8fac899ed98b0ab 88 Gene3D G3DSA:2.40.10.190 3 88 4.3E-23 T 30-10-2018 IPR038661 Ribosomal protein L35A superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0099 ab056c77a763ddccd8fac899ed98b0ab 88 Hamap MF_00573 50S ribosomal protein L35Ae [rpl35ae]. 4 88 23.488 T 30-10-2018 IPR001780 Ribosomal protein L35A GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0099 ab056c77a763ddccd8fac899ed98b0ab 88 ProDom PD012670 RIBOSOMAL L35A 60S RIBONUCLEOPROTEIN L35A L35AE 50S RNA-BINDING TRNA-BINDING SEQUENCE 5 87 2.0E-30 T 30-10-2018 IPR001780 Ribosomal protein L35A GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0099 ab056c77a763ddccd8fac899ed98b0ab 88 Pfam PF01247 Ribosomal protein L35Ae 5 87 7.0E-14 T 30-10-2018 IPR001780 Ribosomal protein L35A GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0099 ab056c77a763ddccd8fac899ed98b0ab 88 SUPERFAMILY SSF50447 5 87 2.47E-22 T 30-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily CL1_1248 f7a1f96b8b24fd3ef4156ab0e417d1d8 108 Gene3D G3DSA:3.30.70.20 71 108 1.3E-9 T 30-10-2018 CL1_1248 f7a1f96b8b24fd3ef4156ab0e417d1d8 108 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 86 97 - T 30-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CL1_1248 f7a1f96b8b24fd3ef4156ab0e417d1d8 108 Gene3D G3DSA:3.30.70.20 35 70 9.6E-6 T 30-10-2018 CL1_1248 f7a1f96b8b24fd3ef4156ab0e417d1d8 108 Pfam PF14697 4Fe-4S dicluster domain 50 103 2.7E-10 T 30-10-2018 CL1_1248 f7a1f96b8b24fd3ef4156ab0e417d1d8 108 SUPERFAMILY SSF54862 38 107 3.93E-25 T 30-10-2018 CL1_1248 f7a1f96b8b24fd3ef4156ab0e417d1d8 108 TIGRFAM TIGR02179 PorD_KorD: 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate family 35 107 1.9E-34 T 30-10-2018 IPR011898 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate GO:0016625|GO:0051539 CL1_1726 4ab0bcd8bcf746556e6782530c4c46cb 640 Gene3D G3DSA:1.10.510.10 266 592 2.2E-58 T 30-10-2018 CL1_1726 4ab0bcd8bcf746556e6782530c4c46cb 640 SUPERFAMILY SSF56112 267 526 9.28E-62 T 30-10-2018 IPR011009 Protein kinase-like domain superfamily CL1_1726 4ab0bcd8bcf746556e6782530c4c46cb 640 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 391 403 - T 30-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 CL1_1726 4ab0bcd8bcf746556e6782530c4c46cb 640 SMART SM00220 272 528 9.3E-44 T 30-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CL1_1726 4ab0bcd8bcf746556e6782530c4c46cb 640 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 278 301 - T 30-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 CL1_1726 4ab0bcd8bcf746556e6782530c4c46cb 640 Pfam PF00069 Protein kinase domain 272 524 1.8E-42 T 30-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CL1_0397 7b4cc819f988e2e2721c909773cb3b93 372 Pfam PF12327 FtsZ family, C-terminal domain 250 342 6.7E-32 T 30-10-2018 IPR024757 Cell division protein FtsZ, C-terminal CL1_0397 7b4cc819f988e2e2721c909773cb3b93 372 ProSitePatterns PS01134 FtsZ protein signature 1. 73 107 - T 30-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 CL1_0397 7b4cc819f988e2e2721c909773cb3b93 372 Gene3D G3DSA:3.30.1330.20 253 363 3.5E-35 T 30-10-2018 IPR037103 Tubulin/FtsZ, C-terminal domain superfamily Reactome: R-HSA-380320 CL1_0397 7b4cc819f988e2e2721c909773cb3b93 372 SMART SM00864 42 233 9.3E-109 T 30-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CL1_0397 7b4cc819f988e2e2721c909773cb3b93 372 SUPERFAMILY SSF52490 36 234 1.02E-70 T 30-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 CL1_0397 7b4cc819f988e2e2721c909773cb3b93 372 Gene3D G3DSA:3.40.50.1440 34 248 1.4E-83 T 30-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 CL1_0397 7b4cc819f988e2e2721c909773cb3b93 372 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 30 354 2.3E-136 T 30-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 CL1_0397 7b4cc819f988e2e2721c909773cb3b93 372 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 38 370 38.408 T 30-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 CL1_0397 7b4cc819f988e2e2721c909773cb3b93 372 SUPERFAMILY SSF55307 235 347 2.52E-38 T 30-10-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 CL1_0397 7b4cc819f988e2e2721c909773cb3b93 372 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 42 202 2.5E-47 T 30-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CL1_0397 7b4cc819f988e2e2721c909773cb3b93 372 SMART SM00865 235 351 1.2E-49 T 30-10-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-380320 CL1_0397 7b4cc819f988e2e2721c909773cb3b93 372 ProSitePatterns PS01135 FtsZ protein signature 2. 126 147 - T 30-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 CL1_0397 7b4cc819f988e2e2721c909773cb3b93 372 PRINTS PR00423 Cell division protein FtsZ signature 217 239 7.7E-44 T 30-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CL1_0397 7b4cc819f988e2e2721c909773cb3b93 372 PRINTS PR00423 Cell division protein FtsZ signature 240 261 7.7E-44 T 30-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CL1_0397 7b4cc819f988e2e2721c909773cb3b93 372 PRINTS PR00423 Cell division protein FtsZ signature 127 147 7.7E-44 T 30-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CL1_0397 7b4cc819f988e2e2721c909773cb3b93 372 PRINTS PR00423 Cell division protein FtsZ signature 155 176 7.7E-44 T 30-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CL1_0669 1cf2f4fcb9ed83188f54346d641c3729 256 Gene3D G3DSA:3.30.1370.10 149 234 5.8E-34 T 30-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 CL1_0669 1cf2f4fcb9ed83188f54346d641c3729 256 Gene3D G3DSA:2.40.50.100 1 57 1.1E-21 T 30-10-2018 CL1_0669 1cf2f4fcb9ed83188f54346d641c3729 256 Pfam PF14382 Exosome complex exonuclease RRP4 N-terminal region 11 46 2.1E-7 T 30-10-2018 IPR025721 Exosome complex component, N-terminal domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CL1_0669 1cf2f4fcb9ed83188f54346d641c3729 256 Pfam PF15985 KH domain 149 195 8.0E-9 T 30-10-2018 IPR004088 K Homology domain, type 1 GO:0003723 CL1_0669 1cf2f4fcb9ed83188f54346d641c3729 256 Gene3D G3DSA:2.40.50.140 58 142 5.1E-22 T 30-10-2018 CL1_0669 1cf2f4fcb9ed83188f54346d641c3729 256 SMART SM00316 63 137 2.3E-8 T 30-10-2018 IPR022967 RNA-binding domain, S1 CL1_0669 1cf2f4fcb9ed83188f54346d641c3729 256 SUPERFAMILY SSF50249 59 152 2.29E-18 T 30-10-2018 IPR012340 Nucleic acid-binding, OB-fold CL1_0669 1cf2f4fcb9ed83188f54346d641c3729 256 SUPERFAMILY SSF54791 148 227 2.85E-18 T 30-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 CL1_0669 1cf2f4fcb9ed83188f54346d641c3729 256 SUPERFAMILY SSF110324 3 58 8.11E-14 T 30-10-2018 CL1_0669 1cf2f4fcb9ed83188f54346d641c3729 256 Hamap MF_00623 Exosome complex component Rrp4 [rrp4]. 7 235 40.257 T 30-10-2018 IPR023474 Exosome complex component Rrp4 GO:0000178|GO:0008143 CL1_0669 1cf2f4fcb9ed83188f54346d641c3729 256 SMART SM00322 146 211 6.2E-9 T 30-10-2018 IPR004087 K Homology domain GO:0003676 CL1_1070 e5c5f06e18c39e7d9a16732f9803b56c 338 Gene3D G3DSA:3.10.450.620 32 133 3.6E-7 T 30-10-2018 CL1_1070 e5c5f06e18c39e7d9a16732f9803b56c 338 Pfam PF08843 Nucleotidyl transferase AbiEii toxin, Type IV TA system 44 270 5.0E-23 T 30-10-2018 IPR014942 Nucleotidyl transferase AbiEii toxin, Type IV TA system CL1_0633 dd336bcb5f96e5f83f13fc4b8f249f0c 384 Gene3D G3DSA:3.90.1150.10 25 379 8.5E-137 T 30-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 CL1_0633 dd336bcb5f96e5f83f13fc4b8f249f0c 384 Gene3D G3DSA:3.40.640.10 35 280 8.5E-137 T 30-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 CL1_0633 dd336bcb5f96e5f83f13fc4b8f249f0c 384 SUPERFAMILY SSF53383 11 383 2.96E-97 T 30-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase CL1_0633 dd336bcb5f96e5f83f13fc4b8f249f0c 384 Pfam PF00266 Aminotransferase class-V 45 370 5.8E-42 T 30-10-2018 IPR000192 Aminotransferase class V domain CL1_0633 dd336bcb5f96e5f83f13fc4b8f249f0c 384 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 202 222 - T 30-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site CL1_0633 dd336bcb5f96e5f83f13fc4b8f249f0c 384 PIRSF PIRSF000524 17 384 3.7E-101 T 30-10-2018 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832|Reactome: R-HSA-389661|Reactome: R-HSA-9033241 CL1_1129 8290fe880efc0f7db6ea2aac9dd8873b 142 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 46 57 - T 30-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CL1_1129 8290fe880efc0f7db6ea2aac9dd8873b 142 Pfam PF13187 4Fe-4S dicluster domain 45 91 1.1E-10 T 30-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CL1_1129 8290fe880efc0f7db6ea2aac9dd8873b 142 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 77 88 - T 30-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CL1_1129 8290fe880efc0f7db6ea2aac9dd8873b 142 Gene3D G3DSA:3.30.70.3270 23 142 8.2E-21 T 30-10-2018 CL1_1129 8290fe880efc0f7db6ea2aac9dd8873b 142 SUPERFAMILY SSF54862 27 113 1.14E-21 T 30-10-2018 CL1_0866 d2cf074936e7e34b32a208304e8a515d 439 SUPERFAMILY SSF52540 13 227 5.1E-15 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_0866 d2cf074936e7e34b32a208304e8a515d 439 Pfam PF13173 AAA domain 43 165 9.4E-21 T 30-10-2018 CL1_1661 2f9f8f9557af56f5be3a6fa1f7688863 380 Gene3D G3DSA:3.30.70.1510 1 83 3.4E-33 T 30-10-2018 CL1_1661 2f9f8f9557af56f5be3a6fa1f7688863 380 Pfam PF02568 Thiamine biosynthesis protein (ThiI) 177 368 1.8E-64 T 30-10-2018 IPR020536 Thil, AANH domain GO:0004810 KEGG: 00730+2.8.1.4 CL1_1661 2f9f8f9557af56f5be3a6fa1f7688863 380 Pfam PF02926 THUMP domain 28 167 2.4E-26 T 30-10-2018 IPR004114 THUMP domain GO:0003723 CL1_1661 2f9f8f9557af56f5be3a6fa1f7688863 380 SMART SM00981 73 167 1.4E-20 T 30-10-2018 IPR004114 THUMP domain GO:0003723 CL1_1661 2f9f8f9557af56f5be3a6fa1f7688863 380 Hamap MF_00021 tRNA sulfurtransferase [thiI]. 1 380 123.842 T 30-10-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 KEGG: 00730+2.8.1.4 CL1_1661 2f9f8f9557af56f5be3a6fa1f7688863 380 SUPERFAMILY SSF52402 177 336 2.43E-49 T 30-10-2018 CL1_1661 2f9f8f9557af56f5be3a6fa1f7688863 380 TIGRFAM TIGR00342 TIGR00342: tRNA sulfurtransferase ThiI 4 365 3.1E-104 T 30-10-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 KEGG: 00730+2.8.1.4 CL1_1661 2f9f8f9557af56f5be3a6fa1f7688863 380 Gene3D G3DSA:3.30.2300.10 84 165 5.9E-29 T 30-10-2018 CL1_1661 2f9f8f9557af56f5be3a6fa1f7688863 380 Gene3D G3DSA:3.40.50.620 177 374 2.3E-63 T 30-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CL1_1661 2f9f8f9557af56f5be3a6fa1f7688863 380 SUPERFAMILY SSF143437 1 175 5.06E-48 T 30-10-2018 CL1_0206 451684544da5982d2f8d311cf9b86938 153 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 23 34 1.1E-13 T 30-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 CL1_0206 451684544da5982d2f8d311cf9b86938 153 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 7 23 1.1E-13 T 30-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 CL1_0206 451684544da5982d2f8d311cf9b86938 153 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 34 53 1.1E-13 T 30-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 CL1_0206 451684544da5982d2f8d311cf9b86938 153 Pfam PF13404 AsnC-type helix-turn-helix domain 7 47 6.2E-17 T 30-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 CL1_0206 451684544da5982d2f8d311cf9b86938 153 Pfam PF01037 Lrp/AsnC ligand binding domain 73 142 8.9E-16 T 30-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CL1_0206 451684544da5982d2f8d311cf9b86938 153 Gene3D G3DSA:3.30.70.920 59 148 5.5E-22 T 30-10-2018 CL1_0206 451684544da5982d2f8d311cf9b86938 153 SUPERFAMILY SSF54909 67 144 1.36E-17 T 30-10-2018 IPR011008 Dimeric alpha-beta barrel CL1_0206 451684544da5982d2f8d311cf9b86938 153 SMART SM00344 7 113 1.6E-43 T 30-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CL1_0206 451684544da5982d2f8d311cf9b86938 153 Gene3D G3DSA:1.10.10.10 4 58 5.9E-22 T 30-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CL1_0206 451684544da5982d2f8d311cf9b86938 153 SUPERFAMILY SSF46785 7 76 1.07E-16 T 30-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CL1_1669 5bc8d3c7f2226a7ad123d6cda6f3d4e8 397 SUPERFAMILY SSF161093 224 395 1.31E-25 T 30-10-2018 IPR036739 SLC41 divalent cation transporters, integral membrane domain superfamily GO:0006812|GO:0008324 CL1_1669 5bc8d3c7f2226a7ad123d6cda6f3d4e8 397 Gene3D G3DSA:1.10.357.20 217 395 6.0E-12 T 30-10-2018 IPR038048 Magnesium transporter MgtE, transmembrane domain CL1_1669 5bc8d3c7f2226a7ad123d6cda6f3d4e8 397 Gene3D G3DSA:1.10.357.20 12 189 3.3E-10 T 30-10-2018 IPR038048 Magnesium transporter MgtE, transmembrane domain CL1_1669 5bc8d3c7f2226a7ad123d6cda6f3d4e8 397 SUPERFAMILY SSF161093 15 189 7.72E-32 T 30-10-2018 IPR036739 SLC41 divalent cation transporters, integral membrane domain superfamily GO:0006812|GO:0008324 CL1_1669 5bc8d3c7f2226a7ad123d6cda6f3d4e8 397 Pfam PF01769 Divalent cation transporter 263 388 6.8E-15 T 30-10-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 CL1_1669 5bc8d3c7f2226a7ad123d6cda6f3d4e8 397 Pfam PF01769 Divalent cation transporter 60 183 1.4E-21 T 30-10-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 CL1_1080 0d10b1629beb58f926d1f513f8a8eafd 445 Pfam PF00145 C-5 cytosine-specific DNA methylase 7 424 4.8E-67 T 30-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 CL1_1080 0d10b1629beb58f926d1f513f8a8eafd 445 SUPERFAMILY SSF53335 7 424 1.92E-92 T 30-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CL1_1080 0d10b1629beb58f926d1f513f8a8eafd 445 Gene3D G3DSA:3.90.120.10 240 412 4.1E-33 T 30-10-2018 CL1_1080 0d10b1629beb58f926d1f513f8a8eafd 445 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 141 155 5.9E-14 T 30-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 CL1_1080 0d10b1629beb58f926d1f513f8a8eafd 445 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 194 207 5.9E-14 T 30-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 CL1_1080 0d10b1629beb58f926d1f513f8a8eafd 445 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 8 24 5.9E-14 T 30-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 CL1_1080 0d10b1629beb58f926d1f513f8a8eafd 445 ProSitePatterns PS00095 C-5 cytosine-specific DNA methylases C-terminal signature. 406 424 - T 30-10-2018 IPR031303 DNA methylase, C-5 cytosine-specific, conserved site KEGG: 00270+2.1.1.37 CL1_1080 0d10b1629beb58f926d1f513f8a8eafd 445 ProSitePatterns PS00094 C-5 cytosine-specific DNA methylases active site. 83 95 - T 30-10-2018 IPR018117 DNA methylase, C-5 cytosine-specific, active site KEGG: 00270+2.1.1.37|Reactome: R-HSA-212300|Reactome: R-HSA-4655427|Reactome: R-HSA-5334118 CL1_1080 0d10b1629beb58f926d1f513f8a8eafd 445 TIGRFAM TIGR00675 dcm: DNA (cytosine-5-)-methyltransferase 9 421 8.3E-54 T 30-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 CL1_1080 0d10b1629beb58f926d1f513f8a8eafd 445 Gene3D G3DSA:3.40.50.150 6 234 1.9E-59 T 30-10-2018 CL1_1334 c680472a6389ede1a59902e9a7b77f64 394 PRINTS PR01035 Tetracycline resistance protein signature 298 318 2.6E-7 T 30-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CL1_1334 c680472a6389ede1a59902e9a7b77f64 394 PRINTS PR01035 Tetracycline resistance protein signature 134 156 2.6E-7 T 30-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CL1_1334 c680472a6389ede1a59902e9a7b77f64 394 PRINTS PR01035 Tetracycline resistance protein signature 333 356 2.6E-7 T 30-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CL1_1334 c680472a6389ede1a59902e9a7b77f64 394 PRINTS PR01035 Tetracycline resistance protein signature 16 32 2.6E-7 T 30-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CL1_1334 c680472a6389ede1a59902e9a7b77f64 394 Pfam PF07690 Major Facilitator Superfamily 12 327 8.6E-39 T 30-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CL1_1334 c680472a6389ede1a59902e9a7b77f64 394 Gene3D G3DSA:1.20.1250.20 2 380 4.4E-52 T 30-10-2018 CL1_1334 c680472a6389ede1a59902e9a7b77f64 394 SUPERFAMILY SSF103473 5 381 1.27E-57 T 30-10-2018 IPR036259 MFS transporter superfamily CL1_1534 90067be8f8473304bdbc73a667732c2a 233 Gene3D G3DSA:1.10.150.240 15 100 8.7E-62 T 30-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 CL1_1534 90067be8f8473304bdbc73a667732c2a 233 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 145 161 3.2E-12 T 30-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 CL1_1534 90067be8f8473304bdbc73a667732c2a 233 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 163 183 3.2E-12 T 30-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 CL1_1534 90067be8f8473304bdbc73a667732c2a 233 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 114 127 3.2E-12 T 30-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 CL1_1534 90067be8f8473304bdbc73a667732c2a 233 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 1 12 3.2E-12 T 30-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 CL1_1534 90067be8f8473304bdbc73a667732c2a 233 SUPERFAMILY SSF56784 1 230 6.4E-51 T 30-10-2018 IPR036412 HAD-like superfamily CL1_1534 90067be8f8473304bdbc73a667732c2a 233 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 104 196 5.8E-13 T 30-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 CL1_1534 90067be8f8473304bdbc73a667732c2a 233 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 96 201 3.4E-9 T 30-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 CL1_1534 90067be8f8473304bdbc73a667732c2a 233 Gene3D G3DSA:3.40.50.1000 3 222 8.7E-62 T 30-10-2018 IPR023214 HAD superfamily CL1_1534 90067be8f8473304bdbc73a667732c2a 233 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 200 2.9E-28 T 30-10-2018 CL1_1534 90067be8f8473304bdbc73a667732c2a 233 TIGRFAM TIGR02253 CTE7: HAD hydrolase, TIGR02253 family 2 226 4.2E-56 T 30-10-2018 IPR011950 HAD-superfamily hydrolase, subfamily IA, CTE7 GO:0016787 Reactome: R-HSA-4085001 CL1_0117 ec7382b8429c503d7035b62afff7479a 331 Pfam PF05343 M42 glutamyl aminopeptidase 42 323 2.2E-83 T 30-10-2018 IPR008007 Peptidase M42 CL1_0117 ec7382b8429c503d7035b62afff7479a 331 PIRSF PIRSF001123 1 331 1.4E-84 T 30-10-2018 IPR008007 Peptidase M42 CL1_0117 ec7382b8429c503d7035b62afff7479a 331 SUPERFAMILY SSF53187 2 330 1.46E-53 T 30-10-2018 CL1_0117 ec7382b8429c503d7035b62afff7479a 331 Gene3D G3DSA:2.40.30.40 64 155 1.7E-112 T 30-10-2018 IPR023367 Peptidase M42, domain 2 CL1_0117 ec7382b8429c503d7035b62afff7479a 331 Gene3D G3DSA:3.40.630.10 8 324 1.7E-112 T 30-10-2018 CL1_0117 ec7382b8429c503d7035b62afff7479a 331 SUPERFAMILY SSF101821 65 172 2.9E-21 T 30-10-2018 CL1_0511 ba6e9873f9bbc6d94b49ea344a1aa365 222 Hamap MF_01218_A Uracil phosphoribosyltransferase [upp]. 9 217 40.111 T 30-10-2018 IPR034331 Uracil phosphoribosyltransferase, archaea GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 CL1_0511 ba6e9873f9bbc6d94b49ea344a1aa365 222 Pfam PF14681 Uracil phosphoribosyltransferase 15 218 8.8E-50 T 30-10-2018 CL1_0511 ba6e9873f9bbc6d94b49ea344a1aa365 222 TIGRFAM TIGR01091 upp: uracil phosphoribosyltransferase 15 218 4.3E-76 T 30-10-2018 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 CL1_0511 ba6e9873f9bbc6d94b49ea344a1aa365 222 SUPERFAMILY SSF53271 13 217 1.09E-56 T 30-10-2018 IPR029057 Phosphoribosyltransferase-like CL1_0511 ba6e9873f9bbc6d94b49ea344a1aa365 222 Gene3D G3DSA:3.40.50.2020 13 217 3.1E-58 T 30-10-2018 CL1_0624 4fb2fc58f07d146fb1408739a808201f 135 Pfam PF00203 Ribosomal protein S19 37 118 3.2E-36 T 30-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0624 4fb2fc58f07d146fb1408739a808201f 135 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 35 124 25.833 T 30-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0624 4fb2fc58f07d146fb1408739a808201f 135 TIGRFAM TIGR01025 uS19_arch: ribosomal protein uS19 6 135 1.0E-65 T 30-10-2018 IPR005713 Ribosomal protein S19A/S15e GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0624 4fb2fc58f07d146fb1408739a808201f 135 PRINTS PR00975 Ribosomal protein S19 family signature 68 87 4.1E-19 T 30-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0624 4fb2fc58f07d146fb1408739a808201f 135 PRINTS PR00975 Ribosomal protein S19 family signature 88 100 4.1E-19 T 30-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0624 4fb2fc58f07d146fb1408739a808201f 135 PRINTS PR00975 Ribosomal protein S19 family signature 100 115 4.1E-19 T 30-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0624 4fb2fc58f07d146fb1408739a808201f 135 SUPERFAMILY SSF54570 36 119 1.96E-31 T 30-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0624 4fb2fc58f07d146fb1408739a808201f 135 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 37 119 5.9E-27 T 30-10-2018 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 CL1_0624 4fb2fc58f07d146fb1408739a808201f 135 Gene3D G3DSA:3.30.860.20 1 135 5.3E-54 T 30-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0624 4fb2fc58f07d146fb1408739a808201f 135 ProSitePatterns PS00323 Ribosomal protein S19 signature. 88 112 - T 30-10-2018 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0624 4fb2fc58f07d146fb1408739a808201f 135 PIRSF PIRSF002144 1 135 3.1E-41 T 30-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0282 c1b0de1ef0c2ab68bbc692107d32a1bc 122 SUPERFAMILY SSF47819 1 120 1.74E-23 T 30-10-2018 IPR010997 HRDC-like superfamily GO:0000166|GO:0003824|GO:0044237 CL1_0282 c1b0de1ef0c2ab68bbc692107d32a1bc 122 Gene3D G3DSA:1.10.287.420 1 54 2.4E-35 T 30-10-2018 CL1_0282 c1b0de1ef0c2ab68bbc692107d32a1bc 122 Pfam PF03874 RNA polymerase Rpb4 11 119 4.1E-6 T 30-10-2018 IPR005574 RNA polymerase subunit RPB4/RPC9 GO:0006352|GO:0030880 CL1_0282 c1b0de1ef0c2ab68bbc692107d32a1bc 122 PIRSF PIRSF005053 1 120 8.4E-30 T 30-10-2018 IPR010924 DNA-directed RNA polymerase subunit F (Rpo4) CL1_0282 c1b0de1ef0c2ab68bbc692107d32a1bc 122 Gene3D G3DSA:1.10.150.80 55 122 2.4E-28 T 30-10-2018 CL1_0594 2331a3f3cd7162386a58aeb053c6bcba 138 SUPERFAMILY SSF53137 10 136 6.54E-39 T 30-10-2018 CL1_0594 2331a3f3cd7162386a58aeb053c6bcba 138 PIRSF PIRSF002131 1 137 1.5E-35 T 30-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 CL1_0594 2331a3f3cd7162386a58aeb053c6bcba 138 TIGRFAM TIGR03628 arch_S11P: ribosomal protein uS11 14 130 1.2E-66 T 30-10-2018 IPR019961 Ribosomal protein S11, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 CL1_0594 2331a3f3cd7162386a58aeb053c6bcba 138 ProSitePatterns PS00054 Ribosomal protein S11 signature. 103 125 - T 30-10-2018 IPR018102 Ribosomal S11, conserved site CL1_0594 2331a3f3cd7162386a58aeb053c6bcba 138 Gene3D G3DSA:3.30.420.80 2 138 5.7E-65 T 30-10-2018 IPR036967 Ribosomal protein S11 superfamily GO:0003735|GO:0005840|GO:0006412 CL1_0594 2331a3f3cd7162386a58aeb053c6bcba 138 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 10 135 23.642 T 30-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 CL1_0594 2331a3f3cd7162386a58aeb053c6bcba 138 Pfam PF00411 Ribosomal protein S11 16 134 3.7E-47 T 30-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 CL1_0150 e02c4b96badf372224928351d9e3293a 246 Gene3D G3DSA:3.40.50.300 1 239 8.8E-58 T 30-10-2018 CL1_0150 e02c4b96badf372224928351d9e3293a 246 TIGRFAM TIGR01978 sufC: FeS assembly ATPase SufC 2 238 2.4E-82 T 30-10-2018 IPR010230 FeS cluster assembly SUF system, ATPase SufC GO:0005524 CL1_0150 e02c4b96badf372224928351d9e3293a 246 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 30-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CL1_0150 e02c4b96badf372224928351d9e3293a 246 Pfam PF00005 ABC transporter 17 167 2.0E-22 T 30-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CL1_0150 e02c4b96badf372224928351d9e3293a 246 SUPERFAMILY SSF52540 2 226 2.55E-48 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_0150 e02c4b96badf372224928351d9e3293a 246 SMART SM00382 26 219 3.9E-8 T 30-10-2018 IPR003593 AAA+ ATPase domain CL1_1155 4e372414571a66595375f616553450d7 188 TIGRFAM TIGR02228 sigpep_I_arch: signal peptidase I 7 152 4.3E-26 T 30-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 CL1_1155 4e372414571a66595375f616553450d7 188 Pfam PF00717 Peptidase S24-like 37 107 1.1E-5 T 30-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CL1_1155 4e372414571a66595375f616553450d7 188 SUPERFAMILY SSF51306 29 126 4.19E-10 T 30-10-2018 IPR036286 LexA/Signal peptidase-like superfamily CL1_2037 d78a7177be82a93adfe5c08491c773b2 171 Pfam PF01928 CYTH domain 2 160 1.5E-25 T 30-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 CL1_2037 d78a7177be82a93adfe5c08491c773b2 171 Gene3D G3DSA:2.40.320.10 1 170 4.4E-49 T 30-10-2018 CL1_2037 d78a7177be82a93adfe5c08491c773b2 171 SUPERFAMILY SSF55154 1 164 7.68E-39 T 30-10-2018 IPR033469 CYTH-like domain superfamily Reactome: R-HSA-196819 CL1_2037 d78a7177be82a93adfe5c08491c773b2 171 SMART SM01118 1 166 9.0E-12 T 30-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 CL1_2037 d78a7177be82a93adfe5c08491c773b2 171 ProDom PD009560 CYCLASE ADENYLATE CYCLASE ADENYLYL CYAB LYASE CLASS CYAB-TYPE THERMOPHILIC MJ0240 2 141 8.0E-48 T 30-10-2018 CL1_2037 d78a7177be82a93adfe5c08491c773b2 171 TIGRFAM TIGR00318 cyaB: putative adenylyl cyclase CyaB 1 164 8.6E-31 T 30-10-2018 IPR008173 Adenylyl cyclase CyaB KEGG: 00230+4.6.1.1 CL1_0096 732c6deeb5f1c4004080004f2a0116e7 103 Pfam PF01850 PIN domain 48 90 2.6E-5 T 30-10-2018 IPR002716 PIN domain CL1_0096 732c6deeb5f1c4004080004f2a0116e7 103 Gene3D G3DSA:3.40.50.1010 1 93 3.6E-12 T 30-10-2018 CL1_0096 732c6deeb5f1c4004080004f2a0116e7 103 SUPERFAMILY SSF88723 3 96 2.61E-9 T 30-10-2018 IPR029060 PIN-like domain superfamily CL1_1592 69c9d016678de0afca02f9ba54844522 400 SUPERFAMILY SSF63867 331 399 5.76E-19 T 30-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CL1_1592 69c9d016678de0afca02f9ba54844522 400 SUPERFAMILY SSF63882 7 180 3.79E-55 T 30-10-2018 IPR036135 MoeA, N-terminal and linker domain superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CL1_1592 69c9d016678de0afca02f9ba54844522 400 Gene3D G3DSA:2.170.190.11 49 145 8.4E-114 T 30-10-2018 CL1_1592 69c9d016678de0afca02f9ba54844522 400 Gene3D G3DSA:3.40.980.10 179 320 8.4E-114 T 30-10-2018 IPR036425 MoaB/Mog-like domain superfamily CL1_1592 69c9d016678de0afca02f9ba54844522 400 Pfam PF03453 MoeA N-terminal region (domain I and II) 8 171 4.2E-41 T 30-10-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CL1_1592 69c9d016678de0afca02f9ba54844522 400 Gene3D G3DSA:3.90.105.10 26 178 8.4E-114 T 30-10-2018 CL1_1592 69c9d016678de0afca02f9ba54844522 400 Gene3D G3DSA:2.40.340.10 329 400 3.2E-25 T 30-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CL1_1592 69c9d016678de0afca02f9ba54844522 400 SMART SM00852 184 321 3.0E-41 T 30-10-2018 IPR001453 MoaB/Mog domain CL1_1592 69c9d016678de0afca02f9ba54844522 400 Pfam PF03454 MoeA C-terminal region (domain IV) 335 399 1.9E-18 T 30-10-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CL1_1592 69c9d016678de0afca02f9ba54844522 400 Pfam PF00994 Probable molybdopterin binding domain 184 320 7.7E-25 T 30-10-2018 IPR001453 MoaB/Mog domain CL1_1592 69c9d016678de0afca02f9ba54844522 400 SUPERFAMILY SSF53218 181 325 1.3E-43 T 30-10-2018 IPR036425 MoaB/Mog-like domain superfamily CL1_1592 69c9d016678de0afca02f9ba54844522 400 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 180 317 1.3E-33 T 30-10-2018 IPR001453 MoaB/Mog domain CL1_1557 fc8e894256e55ecdb857e1060e231e99 462 Pfam PF03008 Archaea bacterial proteins of unknown function 306 403 4.5E-29 T 30-10-2018 IPR004256 Domain of unknown function DUF234, DEXX-box ATPase C-terminal CL1_1557 fc8e894256e55ecdb857e1060e231e99 462 Pfam PF09339 IclR helix-turn-helix domain 241 282 1.0E-6 T 30-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CL1_1557 fc8e894256e55ecdb857e1060e231e99 462 Pfam PF01637 ATPase domain predominantly from Archaea 5 201 4.0E-26 T 30-10-2018 IPR011579 ATPase domain GO:0005524 CL1_1557 fc8e894256e55ecdb857e1060e231e99 462 SUPERFAMILY SSF52980 337 395 4.83E-5 T 30-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CL1_1557 fc8e894256e55ecdb857e1060e231e99 462 SUPERFAMILY SSF46785 234 348 3.34E-12 T 30-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CL1_1557 fc8e894256e55ecdb857e1060e231e99 462 SUPERFAMILY SSF52540 3 238 4.77E-36 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_1557 fc8e894256e55ecdb857e1060e231e99 462 Gene3D G3DSA:1.10.10.10 235 316 4.6E-7 T 30-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CL1_1557 fc8e894256e55ecdb857e1060e231e99 462 Gene3D G3DSA:3.40.50.300 2 169 5.8E-29 T 30-10-2018 CL1_2026 66737d99a4afd097dee4a13fd0825a68 888 Hamap MF_02005 Valine--tRNA ligase [valS]. 2 793 28.876 T 30-10-2018 IPR022874 Valine-tRNA ligase, type 2 GO:0004832 KEGG: 00970+6.1.1.9 CL1_2026 66737d99a4afd097dee4a13fd0825a68 888 Gene3D G3DSA:1.10.730.10 2 750 5.5E-241 T 30-10-2018 CL1_2026 66737d99a4afd097dee4a13fd0825a68 888 SUPERFAMILY SSF50677 187 335 5.62E-51 T 30-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 CL1_2026 66737d99a4afd097dee4a13fd0825a68 888 PRINTS PR00986 Valyl-tRNA synthetase signature 36 47 2.5E-18 T 30-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CL1_2026 66737d99a4afd097dee4a13fd0825a68 888 PRINTS PR00986 Valyl-tRNA synthetase signature 225 242 2.5E-18 T 30-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CL1_2026 66737d99a4afd097dee4a13fd0825a68 888 PRINTS PR00986 Valyl-tRNA synthetase signature 486 504 2.5E-18 T 30-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CL1_2026 66737d99a4afd097dee4a13fd0825a68 888 PRINTS PR00986 Valyl-tRNA synthetase signature 343 356 2.5E-18 T 30-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CL1_2026 66737d99a4afd097dee4a13fd0825a68 888 PRINTS PR00986 Valyl-tRNA synthetase signature 448 469 2.5E-18 T 30-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CL1_2026 66737d99a4afd097dee4a13fd0825a68 888 SUPERFAMILY SSF52374 3 579 5.84E-126 T 30-10-2018 CL1_2026 66737d99a4afd097dee4a13fd0825a68 888 Gene3D G3DSA:3.90.740.10 170 337 5.5E-241 T 30-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 CL1_2026 66737d99a4afd097dee4a13fd0825a68 888 Gene3D G3DSA:3.40.50.620 22 535 5.5E-241 T 30-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CL1_2026 66737d99a4afd097dee4a13fd0825a68 888 SUPERFAMILY SSF47323 586 825 1.33E-61 T 30-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CL1_2026 66737d99a4afd097dee4a13fd0825a68 888 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 43 54 - T 30-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CL1_2026 66737d99a4afd097dee4a13fd0825a68 888 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 14 570 3.0E-139 T 30-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 CL1_2026 66737d99a4afd097dee4a13fd0825a68 888 Pfam PF08264 Anticodon-binding domain of tRNA 614 762 4.5E-39 T 30-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 CL1_2026 66737d99a4afd097dee4a13fd0825a68 888 TIGRFAM TIGR00422 valS: valine--tRNA ligase 3 864 7.3E-271 T 30-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CL1_0643 72e754fd53898bac04db6955ae8180ba 245 Gene3D G3DSA:3.40.50.700 2 165 4.3E-36 T 30-10-2018 IPR037024 [NiFe]-hydrogenase, small subunit, N-terminal domain superfamily CL1_0643 72e754fd53898bac04db6955ae8180ba 245 SUPERFAMILY SSF56770 2 211 2.09E-43 T 30-10-2018 CL1_0643 72e754fd53898bac04db6955ae8180ba 245 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 14 149 2.3E-24 T 30-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CL1_0819 a76c0abdc134f8ca715ae6caf636eefd 341 Gene3D G3DSA:1.25.40.10 48 243 1.9E-32 T 30-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 CL1_0819 a76c0abdc134f8ca715ae6caf636eefd 341 Pfam PF13424 Tetratricopeptide repeat 133 203 1.4E-10 T 30-10-2018 CL1_0819 a76c0abdc134f8ca715ae6caf636eefd 341 Pfam PF13424 Tetratricopeptide repeat 57 121 4.1E-9 T 30-10-2018 CL1_0819 a76c0abdc134f8ca715ae6caf636eefd 341 SMART SM00028 93 126 9.3E-4 T 30-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CL1_0819 a76c0abdc134f8ca715ae6caf636eefd 341 SMART SM00028 134 167 17.0 T 30-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CL1_0819 a76c0abdc134f8ca715ae6caf636eefd 341 SMART SM00028 174 207 13.0 T 30-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CL1_0819 a76c0abdc134f8ca715ae6caf636eefd 341 SMART SM00028 211 244 310.0 T 30-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CL1_0819 a76c0abdc134f8ca715ae6caf636eefd 341 SMART SM00028 55 88 0.07 T 30-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CL1_0819 a76c0abdc134f8ca715ae6caf636eefd 341 SUPERFAMILY SSF48452 51 239 5.69E-26 T 30-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 CL1_0785 1edf9f66ea1682f1367b1f951097f2ff 438 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 1 418 35.917 T 30-10-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CL1_0785 1edf9f66ea1682f1367b1f951097f2ff 438 Gene3D G3DSA:3.90.600.10 329 415 6.9E-8 T 30-10-2018 IPR037123 Phosphoribosylglycinamide synthetase, C-domain superfamily GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CL1_0785 1edf9f66ea1682f1367b1f951097f2ff 438 SUPERFAMILY SSF51246 326 415 3.77E-15 T 30-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 CL1_0785 1edf9f66ea1682f1367b1f951097f2ff 438 Gene3D G3DSA:3.40.50.20 2 94 3.7E-20 T 30-10-2018 CL1_0785 1edf9f66ea1682f1367b1f951097f2ff 438 ProSitePatterns PS00184 Phosphoribosylglycinamide synthetase signature. 290 297 - T 30-10-2018 IPR020559 Phosphoribosylglycinamide synthetase, conserved site GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CL1_0785 1edf9f66ea1682f1367b1f951097f2ff 438 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 102 296 2.1E-59 T 30-10-2018 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CL1_0785 1edf9f66ea1682f1367b1f951097f2ff 438 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 1 415 3.5E-146 T 30-10-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CL1_0785 1edf9f66ea1682f1367b1f951097f2ff 438 Gene3D G3DSA:3.30.470.20 189 328 1.4E-47 T 30-10-2018 CL1_0785 1edf9f66ea1682f1367b1f951097f2ff 438 SUPERFAMILY SSF52440 1 102 4.6E-24 T 30-10-2018 IPR016185 Pre-ATP-grasp domain superfamily CL1_0785 1edf9f66ea1682f1367b1f951097f2ff 438 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 1 101 1.2E-21 T 30-10-2018 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CL1_0785 1edf9f66ea1682f1367b1f951097f2ff 438 SUPERFAMILY SSF56059 103 320 2.3E-47 T 30-10-2018 CL1_0785 1edf9f66ea1682f1367b1f951097f2ff 438 SMART SM01210 328 419 7.8E-17 T 30-10-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CL1_0785 1edf9f66ea1682f1367b1f951097f2ff 438 SMART SM01209 102 296 4.1E-93 T 30-10-2018 CL1_0785 1edf9f66ea1682f1367b1f951097f2ff 438 Gene3D G3DSA:3.30.1490.20 121 187 3.1E-14 T 30-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 CL1_0785 1edf9f66ea1682f1367b1f951097f2ff 438 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 330 415 2.1E-12 T 30-10-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CL1_1588 e04ecb759e8e472dfa207f47b8d0ae32 235 SUPERFAMILY SSF56300 1 235 8.2E-64 T 30-10-2018 CL1_1588 e04ecb759e8e472dfa207f47b8d0ae32 235 Gene3D G3DSA:3.60.21.10 2 235 2.0E-69 T 30-10-2018 IPR029052 Metallo-dependent phosphatase-like CL1_1588 e04ecb759e8e472dfa207f47b8d0ae32 235 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 1 196 8.7E-30 T 30-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 CL1_1588 e04ecb759e8e472dfa207f47b8d0ae32 235 PIRSF PIRSF000883 1 235 7.3E-71 T 30-10-2018 IPR011152 Phosphoesterase MJ0912 CL1_1843 5dc4d5f785ff31d6bf6340d55861da92 408 PIRSF PIRSF005243 4 407 3.0E-107 T 30-10-2018 IPR016440 Rubredoxin-oxygen oxidoreductase GO:0009055|GO:0010181|GO:0016491|GO:0046872 CL1_1843 5dc4d5f785ff31d6bf6340d55861da92 408 SUPERFAMILY SSF56281 8 255 7.21E-44 T 30-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like CL1_1843 5dc4d5f785ff31d6bf6340d55861da92 408 SMART SM00849 39 209 1.0E-25 T 30-10-2018 IPR001279 Metallo-beta-lactamase CL1_1843 5dc4d5f785ff31d6bf6340d55861da92 408 Gene3D G3DSA:3.60.15.10 1 258 6.2E-88 T 30-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like CL1_1843 5dc4d5f785ff31d6bf6340d55861da92 408 SUPERFAMILY SSF52218 262 407 1.22E-26 T 30-10-2018 IPR029039 Flavoprotein-like superfamily CL1_1843 5dc4d5f785ff31d6bf6340d55861da92 408 Pfam PF00753 Metallo-beta-lactamase superfamily 41 185 1.5E-5 T 30-10-2018 IPR001279 Metallo-beta-lactamase CL1_1843 5dc4d5f785ff31d6bf6340d55861da92 408 Gene3D G3DSA:3.40.50.360 259 404 5.2E-27 T 30-10-2018 IPR029039 Flavoprotein-like superfamily CL1_0786 490a1b9c92c1594dfbb1ec76da72bb84 143 PIRSF PIRSF001338 1 143 4.7E-57 T 30-10-2018 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 CL1_0786 490a1b9c92c1594dfbb1ec76da72bb84 143 SUPERFAMILY SSF52255 1 141 4.58E-51 T 30-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 CL1_0786 490a1b9c92c1594dfbb1ec76da72bb84 143 Pfam PF00731 AIR carboxylase 2 142 1.9E-54 T 30-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CL1_0786 490a1b9c92c1594dfbb1ec76da72bb84 143 SMART SM01001 1 143 1.6E-68 T 30-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CL1_0786 490a1b9c92c1594dfbb1ec76da72bb84 143 Gene3D G3DSA:3.40.50.7700 2 143 4.7E-59 T 30-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 CL1_0786 490a1b9c92c1594dfbb1ec76da72bb84 143 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 3 142 7.1E-53 T 30-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CL1_0786 490a1b9c92c1594dfbb1ec76da72bb84 143 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 3 143 24.972 T 30-10-2018 IPR033747 Class I PurE CL1_1452 033994a8f9c4006d203d32479767ea3a 726 SUPERFAMILY SSF52540 36 387 7.72E-48 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_1452 033994a8f9c4006d203d32479767ea3a 726 SUPERFAMILY SSF46785 405 492 2.09E-15 T 30-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CL1_1452 033994a8f9c4006d203d32479767ea3a 726 Gene3D G3DSA:1.10.150.20 643 699 4.8E-22 T 30-10-2018 CL1_1452 033994a8f9c4006d203d32479767ea3a 726 Gene3D G3DSA:1.10.3380.30 411 641 1.3E-72 T 30-10-2018 CL1_1452 033994a8f9c4006d203d32479767ea3a 726 SMART SM00487 20 210 4.4E-31 T 30-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CL1_1452 033994a8f9c4006d203d32479767ea3a 726 Pfam PF14520 Helix-hairpin-helix domain 646 692 1.9E-10 T 30-10-2018 CL1_1452 033994a8f9c4006d203d32479767ea3a 726 Hamap MF_00442 ATP-dependent DNA helicase Hel308 [hel308]. 9 700 30.523 T 30-10-2018 IPR022965 ATP-dependent DNA helicase Hel308 GO:0004386 CL1_1452 033994a8f9c4006d203d32479767ea3a 726 Gene3D G3DSA:3.40.50.300 8 200 1.6E-73 T 30-10-2018 CL1_1452 033994a8f9c4006d203d32479767ea3a 726 SUPERFAMILY SSF158702 493 701 3.66E-58 T 30-10-2018 CL1_1452 033994a8f9c4006d203d32479767ea3a 726 Pfam PF00271 Helicase conserved C-terminal domain 230 372 6.1E-10 T 30-10-2018 IPR001650 Helicase, C-terminal CL1_1452 033994a8f9c4006d203d32479767ea3a 726 Gene3D G3DSA:3.40.50.300 201 399 1.1E-60 T 30-10-2018 CL1_1452 033994a8f9c4006d203d32479767ea3a 726 SMART SM00490 288 374 1.3E-14 T 30-10-2018 IPR001650 Helicase, C-terminal CL1_1452 033994a8f9c4006d203d32479767ea3a 726 SMART SM00278 645 664 0.43 T 30-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CL1_1452 033994a8f9c4006d203d32479767ea3a 726 SMART SM00278 678 697 0.97 T 30-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CL1_1452 033994a8f9c4006d203d32479767ea3a 726 Pfam PF00270 DEAD/DEAH box helicase 26 180 7.8E-26 T 30-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CL1_1545 8168a157566c426dcdfca452574d846c 123 SUPERFAMILY SSF53335 1 108 1.8E-26 T 30-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CL1_1545 8168a157566c426dcdfca452574d846c 123 Gene3D G3DSA:3.40.50.150 1 123 7.5E-29 T 30-10-2018 CL1_1545 8168a157566c426dcdfca452574d846c 123 Pfam PF08241 Methyltransferase domain 1 91 1.1E-18 T 30-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 CL1_1716 98cf63572478b2ab70938484f3b06719 380 Gene3D G3DSA:3.40.50.300 99 375 1.0E-79 T 30-10-2018 CL1_1716 98cf63572478b2ab70938484f3b06719 380 Gene3D G3DSA:1.10.8.60 267 359 1.0E-79 T 30-10-2018 CL1_1716 98cf63572478b2ab70938484f3b06719 380 SMART SM00382 133 268 4.5E-15 T 30-10-2018 IPR003593 AAA+ ATPase domain CL1_1716 98cf63572478b2ab70938484f3b06719 380 Pfam PF09336 Vps4 C terminal oligomerisation domain 342 379 9.7E-6 T 30-10-2018 IPR015415 Vps4 oligomerisation, C-terminal CL1_1716 98cf63572478b2ab70938484f3b06719 380 SUPERFAMILY SSF52540 101 378 1.09E-53 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_1716 98cf63572478b2ab70938484f3b06719 380 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 137 266 3.7E-37 T 30-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CL1_1314 cfd1bfb23183211b06045932ac3c0d4e 498 Hamap MF_01508 Replication factor C large subunit [rfcL]. 4 427 35.004 T 30-10-2018 IPR023935 Replication factor C, large subunit CL1_1314 cfd1bfb23183211b06045932ac3c0d4e 498 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 46 155 5.8E-15 T 30-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CL1_1314 cfd1bfb23183211b06045932ac3c0d4e 498 SUPERFAMILY SSF52540 4 221 1.24E-45 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_1314 cfd1bfb23183211b06045932ac3c0d4e 498 SMART SM00382 42 159 7.5E-12 T 30-10-2018 IPR003593 AAA+ ATPase domain CL1_1314 cfd1bfb23183211b06045932ac3c0d4e 498 Gene3D G3DSA:1.10.8.60 160 225 4.7E-10 T 30-10-2018 CL1_1314 cfd1bfb23183211b06045932ac3c0d4e 498 Gene3D G3DSA:3.40.50.300 4 157 3.1E-37 T 30-10-2018 CL1_0051 59aad9f8a9a03ad8947514921a583d0f 579 Pfam PF01702 Queuine tRNA-ribosyltransferase 109 330 7.5E-42 T 30-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CL1_0051 59aad9f8a9a03ad8947514921a583d0f 579 TIGRFAM TIGR00451 unchar_dom_2: uncharacterized domain 2 485 575 2.6E-10 T 30-10-2018 IPR004521 Uncharacterised domain CHP00451 GO:0003723 CL1_0051 59aad9f8a9a03ad8947514921a583d0f 579 Pfam PF14809 C1 domain of tRNA-guanine transglycosylase dimerisation 357 426 1.0E-41 T 30-10-2018 IPR032729 tRNA-guanine(15) transglycosylase, C1 domain MetaCyc: PWY-6711|MetaCyc: PWY-7923 CL1_0051 59aad9f8a9a03ad8947514921a583d0f 579 Gene3D G3DSA:3.20.20.105 1 356 1.4E-125 T 30-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CL1_0051 59aad9f8a9a03ad8947514921a583d0f 579 SUPERFAMILY SSF51713 4 355 3.66E-118 T 30-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CL1_0051 59aad9f8a9a03ad8947514921a583d0f 579 Gene3D G3DSA:3.10.450.90 427 501 1.7E-28 T 30-10-2018 IPR038250 TGT, patch-forming C2 domain superfamily MetaCyc: PWY-6711|MetaCyc: PWY-7923 CL1_0051 59aad9f8a9a03ad8947514921a583d0f 579 TIGRFAM TIGR00432 arcsn_tRNA_tgt: tRNA-guanine(15) transglycosylase 6 387 6.4E-173 T 30-10-2018 IPR004804 tRNA-guanine(15) transglycosylase GO:0006400|GO:0016763 MetaCyc: PWY-6711|MetaCyc: PWY-7923 CL1_0051 59aad9f8a9a03ad8947514921a583d0f 579 Hamap MF_01634 tRNA-guanine(15) transglycosylase [tgtA]. 6 531 48.72 T 30-10-2018 IPR004804 tRNA-guanine(15) transglycosylase GO:0006400|GO:0016763 MetaCyc: PWY-6711|MetaCyc: PWY-7923 CL1_0051 59aad9f8a9a03ad8947514921a583d0f 579 Gene3D G3DSA:3.90.1020.10 357 426 5.8E-28 T 30-10-2018 IPR038370 TGT, C1 domain superfamily MetaCyc: PWY-6711|MetaCyc: PWY-7923 CL1_0051 59aad9f8a9a03ad8947514921a583d0f 579 Pfam PF01472 PUA domain 506 577 7.4E-15 T 30-10-2018 IPR002478 PUA domain GO:0003723 CL1_0051 59aad9f8a9a03ad8947514921a583d0f 579 Pfam PF14810 Patch-forming domain C2 of tRNA-guanine transglycosylase 436 503 1.3E-23 T 30-10-2018 IPR029402 tRNA-guanine transglycosylase, patch-forming domain C2 MetaCyc: PWY-6711|MetaCyc: PWY-7923 CL1_0051 59aad9f8a9a03ad8947514921a583d0f 579 SUPERFAMILY SSF88802 357 502 1.63E-42 T 30-10-2018 CL1_0051 59aad9f8a9a03ad8947514921a583d0f 579 SMART SM00359 505 579 6.1E-20 T 30-10-2018 IPR002478 PUA domain GO:0003723 CL1_0051 59aad9f8a9a03ad8947514921a583d0f 579 Gene3D G3DSA:2.30.130.10 502 579 5.2E-32 T 30-10-2018 IPR036974 PUA domain superfamily GO:0003723 CL1_0051 59aad9f8a9a03ad8947514921a583d0f 579 TIGRFAM TIGR00449 tgt_general: tRNA-guanine family transglycosylase 6 338 2.7E-90 T 30-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CL1_0051 59aad9f8a9a03ad8947514921a583d0f 579 SUPERFAMILY SSF88697 504 578 7.73E-21 T 30-10-2018 IPR015947 PUA-like superfamily CL1_1788 64c813c8e74874cc03ba4de98eba8791 143 ProDom PD049902 METHYLTRANSFERASE TRANSFERASE PRECURSOR ISOPRENYLCYSTEINE SIGNAL CARBOXYL TRANSMEMBRANE MEMBRANE FAMILY XCC3183 99 140 0.005 T 30-10-2018 CL1_1788 64c813c8e74874cc03ba4de98eba8791 143 Gene3D G3DSA:1.20.120.1630 4 143 3.0E-25 T 30-10-2018 CL1_1788 64c813c8e74874cc03ba4de98eba8791 143 Pfam PF04191 Phospholipid methyltransferase 49 127 1.7E-4 T 30-10-2018 IPR007318 Phospholipid methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825|Reactome: R-HSA-1483191 CL1_1187 1161be0296fc20ff89a3d19576a9c72c 153 Pfam PF04545 Sigma-70, region 4 7 49 7.1E-7 T 30-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 CL1_1187 1161be0296fc20ff89a3d19576a9c72c 153 TIGRFAM TIGR00721 tfx: DNA-binding protein, Tfx family 1 137 1.6E-58 T 30-10-2018 IPR004645 DNA-binding protein Tfx, archaea GO:0003677 CL1_1187 1161be0296fc20ff89a3d19576a9c72c 153 Pfam PF14601 DNA_binding protein, TFX, C-term 52 132 6.8E-24 T 30-10-2018 IPR029291 DNA binding protein Tfx, C-terminal CL1_1187 1161be0296fc20ff89a3d19576a9c72c 153 Gene3D G3DSA:3.30.1190.10 17 135 3.5E-36 T 30-10-2018 IPR036657 DNA-binding protein Tfx superfamily, archaea GO:0003677 CL1_1187 1161be0296fc20ff89a3d19576a9c72c 153 SUPERFAMILY SSF89915 17 120 2.35E-24 T 30-10-2018 IPR036657 DNA-binding protein Tfx superfamily, archaea GO:0003677 CL1_1187 1161be0296fc20ff89a3d19576a9c72c 153 PIRSF PIRSF004932 3 150 1.3E-65 T 30-10-2018 IPR018384 DNA-binding protein Tfx, euryarchaeota GO:0003677 CL1_0630 9c8e0ad78c71b1c7d07be6993ea0be3f 380 Pfam PF09414 RNA ligase 86 240 2.4E-18 T 30-10-2018 IPR021122 RNA ligase domain, REL/Rln2 CL1_0630 9c8e0ad78c71b1c7d07be6993ea0be3f 380 Gene3D G3DSA:3.30.1490.70 70 241 1.5E-69 T 30-10-2018 CL1_0630 9c8e0ad78c71b1c7d07be6993ea0be3f 380 Gene3D G3DSA:3.30.70.3350 244 374 7.9E-37 T 30-10-2018 CL1_0630 9c8e0ad78c71b1c7d07be6993ea0be3f 380 TIGRFAM TIGR01209 TIGR01209: RNA ligase, Pab1020 family 11 380 3.4E-148 T 30-10-2018 IPR001072 RNA ligase, Pab1020 family CL1_0630 9c8e0ad78c71b1c7d07be6993ea0be3f 380 PRINTS PR01048 Hypothetical protein Y414 family signature 355 375 1.9E-54 T 30-10-2018 IPR001072 RNA ligase, Pab1020 family CL1_0630 9c8e0ad78c71b1c7d07be6993ea0be3f 380 PRINTS PR01048 Hypothetical protein Y414 family signature 260 278 1.9E-54 T 30-10-2018 IPR001072 RNA ligase, Pab1020 family CL1_0630 9c8e0ad78c71b1c7d07be6993ea0be3f 380 PRINTS PR01048 Hypothetical protein Y414 family signature 87 100 1.9E-54 T 30-10-2018 IPR001072 RNA ligase, Pab1020 family CL1_0630 9c8e0ad78c71b1c7d07be6993ea0be3f 380 PRINTS PR01048 Hypothetical protein Y414 family signature 164 185 1.9E-54 T 30-10-2018 IPR001072 RNA ligase, Pab1020 family CL1_0630 9c8e0ad78c71b1c7d07be6993ea0be3f 380 PRINTS PR01048 Hypothetical protein Y414 family signature 219 232 1.9E-54 T 30-10-2018 IPR001072 RNA ligase, Pab1020 family CL1_0630 9c8e0ad78c71b1c7d07be6993ea0be3f 380 PRINTS PR01048 Hypothetical protein Y414 family signature 42 56 1.9E-54 T 30-10-2018 IPR001072 RNA ligase, Pab1020 family CL1_0630 9c8e0ad78c71b1c7d07be6993ea0be3f 380 PRINTS PR01048 Hypothetical protein Y414 family signature 108 123 1.9E-54 T 30-10-2018 IPR001072 RNA ligase, Pab1020 family CL1_0630 9c8e0ad78c71b1c7d07be6993ea0be3f 380 PRINTS PR01048 Hypothetical protein Y414 family signature 138 153 1.9E-54 T 30-10-2018 IPR001072 RNA ligase, Pab1020 family CL1_0630 9c8e0ad78c71b1c7d07be6993ea0be3f 380 PRINTS PR01048 Hypothetical protein Y414 family signature 64 82 1.9E-54 T 30-10-2018 IPR001072 RNA ligase, Pab1020 family CL1_0630 9c8e0ad78c71b1c7d07be6993ea0be3f 380 PRINTS PR01048 Hypothetical protein Y414 family signature 291 305 1.9E-54 T 30-10-2018 IPR001072 RNA ligase, Pab1020 family CL1_0630 9c8e0ad78c71b1c7d07be6993ea0be3f 380 Gene3D G3DSA:2.20.25.320 7 67 2.0E-22 T 30-10-2018 CL1_0630 9c8e0ad78c71b1c7d07be6993ea0be3f 380 Gene3D G3DSA:3.30.70.3360 314 362 7.9E-37 T 30-10-2018 CL1_0630 9c8e0ad78c71b1c7d07be6993ea0be3f 380 SUPERFAMILY SSF56091 63 259 3.5E-39 T 30-10-2018 CL1_0630 9c8e0ad78c71b1c7d07be6993ea0be3f 380 Gene3D G3DSA:3.30.470.30 96 197 1.5E-69 T 30-10-2018 CL1_1670 8761d243f0c6c8f39a9e2853131ae271 202 SUPERFAMILY SSF109755 12 127 3.01E-15 T 30-10-2018 CL1_1670 8761d243f0c6c8f39a9e2853131ae271 202 Gene3D G3DSA:1.20.58.220 8 116 2.4E-22 T 30-10-2018 IPR038078 PhoU-like domain superfamily CL1_1670 8761d243f0c6c8f39a9e2853131ae271 202 SUPERFAMILY SSF116726 108 191 1.7E-20 T 30-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 CL1_1670 8761d243f0c6c8f39a9e2853131ae271 202 Pfam PF02080 TrkA-C domain 125 191 3.5E-13 T 30-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CL1_1670 8761d243f0c6c8f39a9e2853131ae271 202 Gene3D G3DSA:3.30.70.1450 117 202 1.1E-23 T 30-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 CL1_1670 8761d243f0c6c8f39a9e2853131ae271 202 Pfam PF01895 PhoU domain 18 100 6.8E-9 T 30-10-2018 IPR026022 PhoU domain CL1_0162 7f58771d1e26b318db4f6e6d934e98bb 476 SUPERFAMILY SSF64182 8 470 2.83E-64 T 30-10-2018 IPR038763 DHH phosphoesterase superfamily CL1_0162 7f58771d1e26b318db4f6e6d934e98bb 476 Gene3D G3DSA:3.90.1640.30 6 236 2.6E-19 T 30-10-2018 CL1_0162 7f58771d1e26b318db4f6e6d934e98bb 476 Pfam PF02272 DHHA1 domain 331 464 8.8E-21 T 30-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 CL1_0162 7f58771d1e26b318db4f6e6d934e98bb 476 Gene3D G3DSA:3.10.310.30 336 468 4.8E-9 T 30-10-2018 CL1_1491 af27b520e554b1c7363eb4d8330df1cc 400 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 20 36 1.3E-13 T 30-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 CL1_1491 af27b520e554b1c7363eb4d8330df1cc 400 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 129 143 1.3E-13 T 30-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 CL1_1491 af27b520e554b1c7363eb4d8330df1cc 400 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 178 191 1.3E-13 T 30-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 CL1_1491 af27b520e554b1c7363eb4d8330df1cc 400 Gene3D G3DSA:3.90.120.10 174 341 1.6E-91 T 30-10-2018 CL1_1491 af27b520e554b1c7363eb4d8330df1cc 400 Pfam PF00145 C-5 cytosine-specific DNA methylase 21 352 6.6E-61 T 30-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 CL1_1491 af27b520e554b1c7363eb4d8330df1cc 400 TIGRFAM TIGR00675 dcm: DNA (cytosine-5-)-methyltransferase 22 350 2.0E-53 T 30-10-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 CL1_1491 af27b520e554b1c7363eb4d8330df1cc 400 Gene3D G3DSA:3.40.50.150 22 345 1.6E-91 T 30-10-2018 CL1_1491 af27b520e554b1c7363eb4d8330df1cc 400 SUPERFAMILY SSF53335 22 354 3.59E-83 T 30-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CL1_1491 af27b520e554b1c7363eb4d8330df1cc 400 ProSitePatterns PS00095 C-5 cytosine-specific DNA methylases C-terminal signature. 334 352 - T 30-10-2018 IPR031303 DNA methylase, C-5 cytosine-specific, conserved site KEGG: 00270+2.1.1.37 CL1_1569 f6c4652b5e2a7be7ec63101e8ec58fb9 161 Gene3D G3DSA:2.60.40.790 2 160 5.6E-32 T 30-10-2018 IPR008978 HSP20-like chaperone CL1_1569 f6c4652b5e2a7be7ec63101e8ec58fb9 161 SUPERFAMILY SSF49764 44 152 7.85E-32 T 30-10-2018 IPR008978 HSP20-like chaperone CL1_1569 f6c4652b5e2a7be7ec63101e8ec58fb9 161 Pfam PF00011 Hsp20/alpha crystallin family 57 152 1.5E-18 T 30-10-2018 IPR002068 Alpha crystallin/Hsp20 domain CL1_0800 0c0a599d739803e71906c09bac613662 465 SUPERFAMILY SSF46977 385 452 4.32E-19 T 30-10-2018 IPR037099 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CL1_0800 0c0a599d739803e71906c09bac613662 465 TIGRFAM TIGR00551 nadB: L-aspartate oxidase 1 447 4.2E-154 T 30-10-2018 IPR005288 L-aspartate oxidase GO:0005737|GO:0008734|GO:0009435|GO:0055114 KEGG: 00250+1.4.3.16|KEGG: 00760+1.4.3.16|MetaCyc: PWY-5316|MetaCyc: PWY-7342 CL1_0800 0c0a599d739803e71906c09bac613662 465 Pfam PF00890 FAD binding domain 5 347 5.3E-69 T 30-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CL1_0800 0c0a599d739803e71906c09bac613662 465 Pfam PF02910 Fumarate reductase flavoprotein C-term 423 448 7.7E-6 T 30-10-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CL1_0800 0c0a599d739803e71906c09bac613662 465 Gene3D G3DSA:1.20.58.100 371 460 3.5E-17 T 30-10-2018 CL1_0800 0c0a599d739803e71906c09bac613662 465 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 3 22 4.4E-11 T 30-10-2018 CL1_0800 0c0a599d739803e71906c09bac613662 465 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 163 181 4.4E-11 T 30-10-2018 CL1_0800 0c0a599d739803e71906c09bac613662 465 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 310 332 4.4E-11 T 30-10-2018 CL1_0800 0c0a599d739803e71906c09bac613662 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 325 332 1.0E-6 T 30-10-2018 CL1_0800 0c0a599d739803e71906c09bac613662 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 166 175 1.0E-6 T 30-10-2018 CL1_0800 0c0a599d739803e71906c09bac613662 465 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 2 24 1.0E-6 T 30-10-2018 CL1_0800 0c0a599d739803e71906c09bac613662 465 Gene3D G3DSA:3.50.50.60 5 354 4.8E-113 T 30-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily CL1_0800 0c0a599d739803e71906c09bac613662 465 SUPERFAMILY SSF51905 5 380 6.85E-47 T 30-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily CL1_0800 0c0a599d739803e71906c09bac613662 465 SUPERFAMILY SSF56425 204 308 7.48E-33 T 30-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 CL1_0800 0c0a599d739803e71906c09bac613662 465 Gene3D G3DSA:3.90.700.10 212 302 4.8E-113 T 30-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 CL1_0097 762503c575b230ced65e891c9a646200 364 SUPERFAMILY SSF47240 5 141 5.68E-15 T 30-10-2018 IPR009078 Ferritin-like superfamily CL1_0097 762503c575b230ced65e891c9a646200 364 Gene3D G3DSA:1.20.1260.10 12 144 3.1E-7 T 30-10-2018 IPR012347 Ferritin-like CL1_0097 762503c575b230ced65e891c9a646200 364 Pfam PF02915 Rubrerythrin 13 137 4.1E-6 T 30-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 CL1_0097 762503c575b230ced65e891c9a646200 364 Pfam PF01988 VIT family 149 353 1.2E-45 T 30-10-2018 IPR008217 Ccc1 family CL1_0545 c2595a7b720725a09fc01c4a2e2a3ad2 105 Gene3D G3DSA:3.30.70.120 1 105 7.9E-38 T 30-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal CL1_0545 c2595a7b720725a09fc01c4a2e2a3ad2 105 SUPERFAMILY SSF54913 1 104 2.03E-34 T 30-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta CL1_0545 c2595a7b720725a09fc01c4a2e2a3ad2 105 PRINTS PR00340 P-II protein signature 75 95 5.1E-24 T 30-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CL1_0545 c2595a7b720725a09fc01c4a2e2a3ad2 105 PRINTS PR00340 P-II protein signature 44 67 5.1E-24 T 30-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CL1_0545 c2595a7b720725a09fc01c4a2e2a3ad2 105 PRINTS PR00340 P-II protein signature 2 17 5.1E-24 T 30-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CL1_0545 c2595a7b720725a09fc01c4a2e2a3ad2 105 Pfam PF00543 Nitrogen regulatory protein P-II 4 97 1.2E-28 T 30-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CL1_0545 c2595a7b720725a09fc01c4a2e2a3ad2 105 SMART SM00938 4 97 3.5E-40 T 30-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CL1_0545 c2595a7b720725a09fc01c4a2e2a3ad2 105 ProSitePatterns PS00638 P-II protein C-terminal region signature. 75 88 - T 30-10-2018 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 CL1_1527 7d5bee741ca112d01ed0d9307e63e25d 211 TIGRFAM TIGR00080 pimt: protein-L-isoaspartate O-methyltransferase 6 206 1.7E-61 T 30-10-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 CL1_1527 7d5bee741ca112d01ed0d9307e63e25d 211 Gene3D G3DSA:3.40.50.150 1 211 1.5E-94 T 30-10-2018 CL1_1527 7d5bee741ca112d01ed0d9307e63e25d 211 ProSitePatterns PS01279 Protein-L-isoaspartate(D-aspartate) O-methyltransferase signature. 128 143 - T 30-10-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 CL1_1527 7d5bee741ca112d01ed0d9307e63e25d 211 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 5 205 5.5E-68 T 30-10-2018 CL1_1527 7d5bee741ca112d01ed0d9307e63e25d 211 SUPERFAMILY SSF53335 2 205 2.41E-53 T 30-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CL1_1527 7d5bee741ca112d01ed0d9307e63e25d 211 Hamap MF_00090 Protein-L-isoaspartate O-methyltransferase [pcm]. 1 209 41.333 T 30-10-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 CL1_1664 77df06e2d96b0e878f5588f05c6356f6 272 SUPERFAMILY SSF53686 3 269 7.86E-63 T 30-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme CL1_1664 77df06e2d96b0e878f5588f05c6356f6 272 Gene3D G3DSA:3.40.50.1100 3 262 6.4E-70 T 30-10-2018 CL1_1664 77df06e2d96b0e878f5588f05c6356f6 272 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 3 256 4.2E-44 T 30-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme CL1_1664 77df06e2d96b0e878f5588f05c6356f6 272 Gene3D G3DSA:3.40.50.1100 19 119 6.4E-70 T 30-10-2018 CL1_1622 6472b4d46ee4770fae4c15b4914b73ce 254 TIGRFAM TIGR01769 GGGP: phosphoglycerol geranylgeranyltransferase 21 227 1.1E-84 T 30-10-2018 IPR010946 Geranylgeranylglyceryl phosphate synthase GO:0000287|GO:0005737|GO:0006650|GO:0047294 KEGG: 00564+2.5.1.41|MetaCyc: PWY-6349 CL1_1622 6472b4d46ee4770fae4c15b4914b73ce 254 Hamap MF_00112 Geranylgeranylglyceryl phosphate synthase [pcrB]. 14 246 35.639 T 30-10-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 CL1_1622 6472b4d46ee4770fae4c15b4914b73ce 254 Gene3D G3DSA:3.20.20.390 3 251 2.1E-100 T 30-10-2018 IPR038597 GGGP/HepGP synthase superfamily CL1_1622 6472b4d46ee4770fae4c15b4914b73ce 254 Pfam PF01884 PcrB family 16 237 1.1E-69 T 30-10-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 CL1_1622 6472b4d46ee4770fae4c15b4914b73ce 254 SUPERFAMILY SSF51395 18 239 2.64E-48 T 30-10-2018 CL1_1622 6472b4d46ee4770fae4c15b4914b73ce 254 TIGRFAM TIGR01768 GGGP-family: geranylgeranylglyceryl phosphate synthase family protein 20 234 5.1E-79 T 30-10-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 CL1_1741 bb860654864dbe6f66de7d9c42ad5388 123 TIGRFAM TIGR03677 eL8_ribo: ribosomal protein eL8 6 121 5.5E-58 T 30-10-2018 IPR022481 Ribosomal protein L7Ae, archaea GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CL1_1741 bb860654864dbe6f66de7d9c42ad5388 123 Gene3D G3DSA:3.30.1330.30 1 123 1.5E-43 T 30-10-2018 IPR029064 50S ribosomal protein L30e-like CL1_1741 bb860654864dbe6f66de7d9c42ad5388 123 PRINTS PR00881 Ribosomal protein L7A/RS6 family signature 32 46 1.6E-22 T 30-10-2018 IPR018492 Ribosomal protein L7Ae/L8/Nhp2 family CL1_1741 bb860654864dbe6f66de7d9c42ad5388 123 PRINTS PR00881 Ribosomal protein L7A/RS6 family signature 67 77 1.6E-22 T 30-10-2018 IPR018492 Ribosomal protein L7Ae/L8/Nhp2 family CL1_1741 bb860654864dbe6f66de7d9c42ad5388 123 PRINTS PR00881 Ribosomal protein L7A/RS6 family signature 77 91 1.6E-22 T 30-10-2018 IPR018492 Ribosomal protein L7Ae/L8/Nhp2 family CL1_1741 bb860654864dbe6f66de7d9c42ad5388 123 PRINTS PR00881 Ribosomal protein L7A/RS6 family signature 51 64 1.6E-22 T 30-10-2018 IPR018492 Ribosomal protein L7Ae/L8/Nhp2 family CL1_1741 bb860654864dbe6f66de7d9c42ad5388 123 Pfam PF01248 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family 18 110 1.0E-32 T 30-10-2018 IPR004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45 CL1_1741 bb860654864dbe6f66de7d9c42ad5388 123 ProSitePatterns PS01082 Ribosomal protein L7Ae signature. 70 87 - T 30-10-2018 IPR004037 Ribosomal protein L7Ae conserved site GO:0042254|GO:1990904 Reactome: R-HSA-6791226 CL1_1741 bb860654864dbe6f66de7d9c42ad5388 123 SUPERFAMILY SSF55315 4 120 1.91E-40 T 30-10-2018 IPR029064 50S ribosomal protein L30e-like CL1_1741 bb860654864dbe6f66de7d9c42ad5388 123 Hamap MF_00326 50S ribosomal protein L7Ae [rpl7ae]. 3 122 35.59 T 30-10-2018 IPR022481 Ribosomal protein L7Ae, archaea GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CL1_1741 bb860654864dbe6f66de7d9c42ad5388 123 PRINTS PR00884 Ribosomal protein HS6 signature 50 61 1.9E-31 T 30-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 CL1_1741 bb860654864dbe6f66de7d9c42ad5388 123 PRINTS PR00884 Ribosomal protein HS6 signature 91 107 1.9E-31 T 30-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 CL1_1741 bb860654864dbe6f66de7d9c42ad5388 123 PRINTS PR00884 Ribosomal protein HS6 signature 77 87 1.9E-31 T 30-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 CL1_1741 bb860654864dbe6f66de7d9c42ad5388 123 PRINTS PR00884 Ribosomal protein HS6 signature 6 17 1.9E-31 T 30-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 CL1_1741 bb860654864dbe6f66de7d9c42ad5388 123 PRINTS PR00884 Ribosomal protein HS6 signature 40 50 1.9E-31 T 30-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 CL1_0659 1fe439a71c6dfd514067964fd0736df7 334 Gene3D G3DSA:3.30.360.10 167 308 1.9E-87 T 30-10-2018 CL1_0659 1fe439a71c6dfd514067964fd0736df7 334 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 201 223 - T 30-10-2018 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 CL1_0659 1fe439a71c6dfd514067964fd0736df7 334 PIRSF PIRSF036497 1 333 7.7E-81 T 30-10-2018 IPR022697 Homoserine dehydrogenase lacking ACT domain GO:0004412 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 CL1_0659 1fe439a71c6dfd514067964fd0736df7 334 Gene3D G3DSA:3.40.50.720 7 325 1.9E-87 T 30-10-2018 CL1_0659 1fe439a71c6dfd514067964fd0736df7 334 SUPERFAMILY SSF51735 3 177 1.39E-28 T 30-10-2018 IPR036291 NAD(P)-binding domain superfamily CL1_0659 1fe439a71c6dfd514067964fd0736df7 334 Pfam PF00742 Homoserine dehydrogenase 156 325 6.5E-47 T 30-10-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 CL1_0659 1fe439a71c6dfd514067964fd0736df7 334 SUPERFAMILY SSF55347 156 312 1.31E-35 T 30-10-2018 CL1_0659 1fe439a71c6dfd514067964fd0736df7 334 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 5 97 1.5E-5 T 30-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CL1_0042 cbcd939bbac5b4f161c43dd882723828 153 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 15 147 2.5E-48 T 30-10-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CL1_0042 cbcd939bbac5b4f161c43dd882723828 153 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 14 148 3.7E-54 T 30-10-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CL1_0042 cbcd939bbac5b4f161c43dd882723828 153 SUPERFAMILY SSF52121 5 152 5.49E-56 T 30-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CL1_0042 cbcd939bbac5b4f161c43dd882723828 153 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 10 151 29.897 T 30-10-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CL1_0042 cbcd939bbac5b4f161c43dd882723828 153 Gene3D G3DSA:3.40.50.960 5 153 8.3E-57 T 30-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CL1_1435 52ba7a6941a20fa85d849133b2a92c8e 201 Pfam PF01899 Na+/H+ ion antiporter subunit 41 199 3.8E-41 T 30-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 CL1_1435 52ba7a6941a20fa85d849133b2a92c8e 201 PIRSF PIRSF019239 29 201 2.4E-50 T 30-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 CL1_1935 79a4131ad549454c825750b44479a9c7 279 Gene3D G3DSA:3.30.300.110 20 87 3.1E-28 T 30-10-2018 CL1_1935 79a4131ad549454c825750b44479a9c7 279 Gene3D G3DSA:3.40.50.150 88 279 3.8E-57 T 30-10-2018 CL1_1935 79a4131ad549454c825750b44479a9c7 279 Pfam PF02475 Met-10+ like-protein 30 224 4.3E-67 T 30-10-2018 IPR030382 SAM-dependent methyltransferase TRM5/TYW2-type Reactome: R-HSA-6782861 CL1_1935 79a4131ad549454c825750b44479a9c7 279 SUPERFAMILY SSF53335 20 277 3.89E-69 T 30-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CL1_1935 79a4131ad549454c825750b44479a9c7 279 Hamap MF_01922 tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase [taw2]. 27 277 40.766 T 30-10-2018 IPR030867 tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase GO:0006400|GO:0016765 MetaCyc: PWY-7286 CL1_0056 1b4c8bdc5a688547a42dfe014f8ebe09 219 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 84 188 6.6E-9 T 30-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 CL1_0056 1b4c8bdc5a688547a42dfe014f8ebe09 219 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 103 184 2.5E-8 T 30-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 CL1_0056 1b4c8bdc5a688547a42dfe014f8ebe09 219 Gene3D G3DSA:1.10.150.240 17 86 1.3E-33 T 30-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 CL1_0056 1b4c8bdc5a688547a42dfe014f8ebe09 219 Gene3D G3DSA:3.40.50.1000 6 192 1.3E-33 T 30-10-2018 IPR023214 HAD superfamily CL1_0056 1b4c8bdc5a688547a42dfe014f8ebe09 219 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 152 172 2.1E-8 T 30-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 CL1_0056 1b4c8bdc5a688547a42dfe014f8ebe09 219 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 2 13 2.1E-8 T 30-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 CL1_0056 1b4c8bdc5a688547a42dfe014f8ebe09 219 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 179 192 2.1E-8 T 30-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 CL1_0056 1b4c8bdc5a688547a42dfe014f8ebe09 219 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 101 114 2.1E-8 T 30-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 CL1_0056 1b4c8bdc5a688547a42dfe014f8ebe09 219 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 190 1.1E-26 T 30-10-2018 CL1_0056 1b4c8bdc5a688547a42dfe014f8ebe09 219 SUPERFAMILY SSF56784 1 217 7.15E-44 T 30-10-2018 IPR036412 HAD-like superfamily CL1_1821 621009861b04b49cc5730960be115ed8 339 Pfam PF00155 Aminotransferase class I and II 23 329 7.1E-48 T 30-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CL1_1821 621009861b04b49cc5730960be115ed8 339 Gene3D G3DSA:3.40.640.10 44 252 3.2E-98 T 30-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 CL1_1821 621009861b04b49cc5730960be115ed8 339 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 2 333 53.175 T 30-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 CL1_1821 621009861b04b49cc5730960be115ed8 339 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 4 331 5.7E-93 T 30-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 CL1_1821 621009861b04b49cc5730960be115ed8 339 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 202 211 - T 30-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 CL1_1821 621009861b04b49cc5730960be115ed8 339 Gene3D G3DSA:3.90.1150.10 11 328 3.2E-98 T 30-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 CL1_1821 621009861b04b49cc5730960be115ed8 339 SUPERFAMILY SSF53383 14 330 4.92E-78 T 30-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase CL1_1629 06e72e9d9811285e543008332aa4d4e0 259 Gene3D G3DSA:3.40.50.300 4 233 9.9E-67 T 30-10-2018 CL1_1629 06e72e9d9811285e543008332aa4d4e0 259 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 6 212 3.5E-24 T 30-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain CL1_1629 06e72e9d9811285e543008332aa4d4e0 259 PIRSF PIRSF003092 1 259 2.1E-65 T 30-10-2018 IPR025501 ATP binding protein MinD CL1_1629 06e72e9d9811285e543008332aa4d4e0 259 SUPERFAMILY SSF52540 3 236 3.36E-58 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_1629 06e72e9d9811285e543008332aa4d4e0 259 SMART SM00382 3 163 0.0061 T 30-10-2018 IPR003593 AAA+ ATPase domain CL1_1629 06e72e9d9811285e543008332aa4d4e0 259 TIGRFAM TIGR01969 minD_arch: cell division ATPase MinD 4 251 3.1E-117 T 30-10-2018 IPR010224 ATP binding protein MinD, archaea CL1_0622 bb5ff80fa1fcb074a51d2bb5e8d47483 210 SMART SM00322 38 104 9.6E-8 T 30-10-2018 IPR004087 K Homology domain GO:0003676 CL1_0622 bb5ff80fa1fcb074a51d2bb5e8d47483 210 SUPERFAMILY SSF54821 86 186 3.4E-26 T 30-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0622 bb5ff80fa1fcb074a51d2bb5e8d47483 210 Gene3D G3DSA:3.30.1140.32 87 210 3.0E-42 T 30-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0622 bb5ff80fa1fcb074a51d2bb5e8d47483 210 SUPERFAMILY SSF54814 7 93 6.28E-26 T 30-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 CL1_0622 bb5ff80fa1fcb074a51d2bb5e8d47483 210 TIGRFAM TIGR01008 uS3_euk_arch: ribosomal protein uS3 3 196 3.6E-94 T 30-10-2018 IPR005703 Ribosomal protein S3, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0622 bb5ff80fa1fcb074a51d2bb5e8d47483 210 Pfam PF00189 Ribosomal protein S3, C-terminal domain 99 182 2.4E-24 T 30-10-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0622 bb5ff80fa1fcb074a51d2bb5e8d47483 210 Pfam PF07650 KH domain 17 88 3.1E-15 T 30-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0622 bb5ff80fa1fcb074a51d2bb5e8d47483 210 Hamap MF_01309_A 30S ribosomal protein S3 [rpsC]. 2 197 42.521 T 30-10-2018 IPR027488 Ribosomal protein S3, archaeal GO:0003735|GO:0006412|GO:0015935 CL1_0622 bb5ff80fa1fcb074a51d2bb5e8d47483 210 Gene3D G3DSA:3.30.300.20 1 86 6.6E-30 T 30-10-2018 IPR015946 K homology domain-like, alpha/beta CL1_0242 56a27f585fe4e8ad7fb52be4e636032b 98 SMART SM00418 10 92 1.4E-15 T 30-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CL1_0242 56a27f585fe4e8ad7fb52be4e636032b 98 Gene3D G3DSA:1.10.10.10 5 97 1.9E-22 T 30-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CL1_0242 56a27f585fe4e8ad7fb52be4e636032b 98 Pfam PF12840 Helix-turn-helix domain 11 64 1.1E-14 T 30-10-2018 CL1_0242 56a27f585fe4e8ad7fb52be4e636032b 98 SUPERFAMILY SSF46785 4 94 8.53E-24 T 30-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CL1_0558 729455130f950cd618e82706196510c5 966 Gene3D G3DSA:1.10.10.720 865 916 2.8E-47 T 30-10-2018 CL1_0558 729455130f950cd618e82706196510c5 966 SUPERFAMILY SSF50677 210 443 4.01E-33 T 30-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 CL1_0558 729455130f950cd618e82706196510c5 966 Gene3D G3DSA:3.30.2320.20 834 966 2.8E-47 T 30-10-2018 CL1_0558 729455130f950cd618e82706196510c5 966 SUPERFAMILY SSF47323 712 904 1.05E-39 T 30-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CL1_0558 729455130f950cd618e82706196510c5 966 SUPERFAMILY SSF52374 5 694 2.69E-100 T 30-10-2018 CL1_0558 729455130f950cd618e82706196510c5 966 Gene3D G3DSA:1.10.730.10 690 809 8.3E-34 T 30-10-2018 CL1_0558 729455130f950cd618e82706196510c5 966 Hamap MF_00049_A Leucine--tRNA ligase [leuS]. 6 966 18.388 T 30-10-2018 IPR020791 Leucine-tRNA ligase, archaeal GO:0000166|GO:0004823|GO:0005524|GO:0005737|GO:0006429 KEGG: 00970+6.1.1.4 CL1_0558 729455130f950cd618e82706196510c5 966 Pfam PF08264 Anticodon-binding domain of tRNA 725 860 2.0E-31 T 30-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 CL1_0558 729455130f950cd618e82706196510c5 966 TIGRFAM TIGR00395 leuS_arch: leucine--tRNA ligase 8 966 0.0 T 30-10-2018 IPR004493 Leucyl-tRNA synthetase, class Ia, archaeal/eukaryotic cytosolic GO:0000166|GO:0004823|GO:0005524|GO:0005737|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CL1_0558 729455130f950cd618e82706196510c5 966 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 12 689 9.2E-67 T 30-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 CL1_0558 729455130f950cd618e82706196510c5 966 Gene3D G3DSA:3.40.50.620 9 688 2.9E-301 T 30-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CL1_0558 729455130f950cd618e82706196510c5 966 Gene3D G3DSA:3.90.740.10 205 451 2.9E-301 T 30-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 CL1_0558 729455130f950cd618e82706196510c5 966 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 43 54 - T 30-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CL1_1046 130d7390aecec22ee665bf3acdaefb3d 152 ProSitePatterns PS01284 Thermonuclease family signature 2. 100 110 - T 30-10-2018 IPR002071 Thermonuclease active site GO:0003676|GO:0004518 Reactome: R-HSA-6802952 CL1_1046 130d7390aecec22ee665bf3acdaefb3d 152 SMART SM00318 25 151 1.1E-8 T 30-10-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold Reactome: R-HSA-6802952 CL1_1046 130d7390aecec22ee665bf3acdaefb3d 152 Gene3D G3DSA:2.40.50.90 23 148 1.6E-20 T 30-10-2018 IPR035437 SNase-like, OB-fold superfamily CL1_1046 130d7390aecec22ee665bf3acdaefb3d 152 Pfam PF00565 Staphylococcal nuclease homologue 55 141 3.6E-10 T 30-10-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold Reactome: R-HSA-6802952 CL1_1046 130d7390aecec22ee665bf3acdaefb3d 152 SUPERFAMILY SSF50199 27 144 4.18E-22 T 30-10-2018 CL1_1390 4ea6a368f7229517c9a9e44e290c5157 308 Gene3D G3DSA:1.10.4200.10 25 293 4.4E-59 T 30-10-2018 CL1_1390 4ea6a368f7229517c9a9e44e290c5157 308 Pfam PF01874 ATP:dephospho-CoA triphosphoribosyl transferase 9 286 4.3E-49 T 30-10-2018 IPR002736 Triphosphoribosyl-dephospho-CoA protein GO:0005524|GO:0016310|GO:0046917 MetaCyc: PWY-5796 CL1_0190 8bb72c535d69e5642334ccd8e8c3fec2 176 PIRSF PIRSF019239 4 176 9.5E-55 T 30-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 CL1_0190 8bb72c535d69e5642334ccd8e8c3fec2 176 Pfam PF01899 Na+/H+ ion antiporter subunit 15 153 1.0E-45 T 30-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 CL1_0303 09728e47c094c8aa0b4ed55239bdfba4 176 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 91 123 5.8E-8 T 30-10-2018 IPR001451 Hexapeptide repeat CL1_0303 09728e47c094c8aa0b4ed55239bdfba4 176 Gene3D G3DSA:2.160.10.10 3 175 3.4E-64 T 30-10-2018 CL1_0303 09728e47c094c8aa0b4ed55239bdfba4 176 SUPERFAMILY SSF51161 7 171 2.08E-51 T 30-10-2018 IPR011004 Trimeric LpxA-like superfamily CL1_0370 dfbb3af98a00dcbd89abca5a0de58184 1228 SUPERFAMILY SSF52540 326 625 5.04E-38 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_0370 dfbb3af98a00dcbd89abca5a0de58184 1228 SUPERFAMILY SSF56712 637 1219 6.54E-144 T 30-10-2018 IPR023405 DNA topoisomerase, type IA, core domain CL1_0370 dfbb3af98a00dcbd89abca5a0de58184 1228 Pfam PF01131 DNA topoisomerase 820 1209 2.4E-81 T 30-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CL1_0370 dfbb3af98a00dcbd89abca5a0de58184 1228 Gene3D G3DSA:2.60.510.20 877 1117 1.6E-142 T 30-10-2018 CL1_0370 dfbb3af98a00dcbd89abca5a0de58184 1228 SUPERFAMILY SSF52540 41 243 2.39E-34 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_0370 dfbb3af98a00dcbd89abca5a0de58184 1228 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 855 873 2.3E-26 T 30-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CL1_0370 dfbb3af98a00dcbd89abca5a0de58184 1228 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 1133 1147 2.3E-26 T 30-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CL1_0370 dfbb3af98a00dcbd89abca5a0de58184 1228 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 769 782 2.3E-26 T 30-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CL1_0370 dfbb3af98a00dcbd89abca5a0de58184 1228 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 958 967 2.3E-26 T 30-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CL1_0370 dfbb3af98a00dcbd89abca5a0de58184 1228 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 1039 1055 2.3E-26 T 30-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CL1_0370 dfbb3af98a00dcbd89abca5a0de58184 1228 Gene3D G3DSA:1.10.290.10 926 1050 1.6E-142 T 30-10-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 CL1_0370 dfbb3af98a00dcbd89abca5a0de58184 1228 Gene3D G3DSA:3.40.50.300 545 629 6.5E-14 T 30-10-2018 CL1_0370 dfbb3af98a00dcbd89abca5a0de58184 1228 Gene3D G3DSA:3.40.50.300 320 501 1.0E-32 T 30-10-2018 CL1_0370 dfbb3af98a00dcbd89abca5a0de58184 1228 SMART SM00487 81 331 3.6E-22 T 30-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CL1_0370 dfbb3af98a00dcbd89abca5a0de58184 1228 Gene3D G3DSA:3.40.50.300 65 319 4.5E-82 T 30-10-2018 CL1_0370 dfbb3af98a00dcbd89abca5a0de58184 1228 Gene3D G3DSA:1.10.460.10 825 1213 1.6E-142 T 30-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 CL1_0370 dfbb3af98a00dcbd89abca5a0de58184 1228 Pfam PF00270 DEAD/DEAH box helicase 88 222 1.6E-10 T 30-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CL1_0370 dfbb3af98a00dcbd89abca5a0de58184 1228 Hamap MF_01125 Reverse gyrase [rgy]. 1 1220 64.929 T 30-10-2018 IPR005736 Reverse gyrase GO:0003677|GO:0003916|GO:0006265 CL1_0370 dfbb3af98a00dcbd89abca5a0de58184 1228 SMART SM00437 916 1172 6.0E-103 T 30-10-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 CL1_0370 dfbb3af98a00dcbd89abca5a0de58184 1228 SMART SM00436 796 883 4.5E-42 T 30-10-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 CL1_0370 dfbb3af98a00dcbd89abca5a0de58184 1228 SMART SM00493 642 795 7.3E-45 T 30-10-2018 IPR006171 TOPRIM domain CL1_0370 dfbb3af98a00dcbd89abca5a0de58184 1228 Pfam PF01751 Toprim domain 644 805 9.0E-29 T 30-10-2018 IPR006171 TOPRIM domain CL1_0370 dfbb3af98a00dcbd89abca5a0de58184 1228 Gene3D G3DSA:3.40.50.140 631 819 1.1E-30 T 30-10-2018 CL1_0370 dfbb3af98a00dcbd89abca5a0de58184 1228 TIGRFAM TIGR01054 rgy: reverse gyrase 2 1218 0.0 T 30-10-2018 IPR005736 Reverse gyrase GO:0003677|GO:0003916|GO:0006265 CL1_0535 9bccc0bca2c7dcaac3356f0e2502d0a3 227 Gene3D G3DSA:3.30.70.260 127 205 2.7E-90 T 30-10-2018 CL1_0535 9bccc0bca2c7dcaac3356f0e2502d0a3 227 SUPERFAMILY SSF75445 131 207 3.79E-25 T 30-10-2018 CL1_0535 9bccc0bca2c7dcaac3356f0e2502d0a3 227 TIGRFAM TIGR00021 rpiA: ribose 5-phosphate isomerase A 4 223 2.5E-82 T 30-10-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 CL1_0535 9bccc0bca2c7dcaac3356f0e2502d0a3 227 SUPERFAMILY SSF100950 2 149 4.05E-46 T 30-10-2018 IPR037171 NagB/RpiA transferase-like CL1_0535 9bccc0bca2c7dcaac3356f0e2502d0a3 227 Gene3D G3DSA:3.40.50.1360 5 221 2.7E-90 T 30-10-2018 CL1_0535 9bccc0bca2c7dcaac3356f0e2502d0a3 227 Pfam PF06026 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) 51 221 3.6E-66 T 30-10-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 CL1_0535 9bccc0bca2c7dcaac3356f0e2502d0a3 227 Hamap MF_00170 Ribose-5-phosphate isomerase A [rpiA]. 1 225 36.49 T 30-10-2018 IPR020672 Ribose-5-phosphate isomerase, type A, subgroup GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 CL1_0758 e79bf805254534e45b3b236178c51052 185 SUPERFAMILY SSF88798 1 78 2.22E-21 T 30-10-2018 IPR036898 RNA polymerase Rpb7-like, N-terminal domain superfamily GO:0003899|GO:0006351 CL1_0758 e79bf805254534e45b3b236178c51052 185 Pfam PF03876 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 8 77 2.2E-19 T 30-10-2018 IPR005576 RNA polymerase Rpb7, N-terminal GO:0003899|GO:0006351 CL1_0758 e79bf805254534e45b3b236178c51052 185 Gene3D G3DSA:2.40.50.140 82 185 1.9E-32 T 30-10-2018 CL1_0758 e79bf805254534e45b3b236178c51052 185 Gene3D G3DSA:3.30.1490.120 1 81 4.7E-32 T 30-10-2018 IPR036898 RNA polymerase Rpb7-like, N-terminal domain superfamily GO:0003899|GO:0006351 CL1_0758 e79bf805254534e45b3b236178c51052 185 SMART SM00316 80 166 4.3E-16 T 30-10-2018 IPR022967 RNA-binding domain, S1 CL1_0758 e79bf805254534e45b3b236178c51052 185 TIGRFAM TIGR00448 rpoE: DNA-directed RNA polymerase 1 179 5.5E-68 T 30-10-2018 IPR004519 DNA-directed RNA polymerase, subunit E/RPC8 GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-1834949|Reactome: R-HSA-73780|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071 CL1_0758 e79bf805254534e45b3b236178c51052 185 Pfam PF00575 S1 RNA binding domain 78 147 3.8E-14 T 30-10-2018 IPR003029 S1 domain GO:0003676 CL1_0758 e79bf805254534e45b3b236178c51052 185 SUPERFAMILY SSF50249 80 179 2.76E-24 T 30-10-2018 IPR012340 Nucleic acid-binding, OB-fold CL1_0151 8807ef07b4bb5fbc86fef58d1d9deb16 634 SUPERFAMILY SSF52540 35 413 4.03E-37 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_0151 8807ef07b4bb5fbc86fef58d1d9deb16 634 Gene3D G3DSA:3.30.230.10 431 634 1.5E-77 T 30-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CL1_0151 8807ef07b4bb5fbc86fef58d1d9deb16 634 SMART SM00382 58 317 2.3E-5 T 30-10-2018 IPR003593 AAA+ ATPase domain CL1_0151 8807ef07b4bb5fbc86fef58d1d9deb16 634 TIGRFAM TIGR00764 lon_rel: putative ATP-dependent protease 23 628 0.0 T 30-10-2018 IPR004663 Lon protease, archaeal GO:0004176|GO:0005524|GO:0030163 CL1_0151 8807ef07b4bb5fbc86fef58d1d9deb16 634 SUPERFAMILY SSF54211 439 612 5.31E-43 T 30-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CL1_0151 8807ef07b4bb5fbc86fef58d1d9deb16 634 Pfam PF01078 Magnesium chelatase, subunit ChlI 40 92 1.5E-9 T 30-10-2018 IPR000523 Magnesium chelatase ChlI domain CL1_0151 8807ef07b4bb5fbc86fef58d1d9deb16 634 Pfam PF13654 AAA domain 182 410 1.4E-23 T 30-10-2018 CL1_0151 8807ef07b4bb5fbc86fef58d1d9deb16 634 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 435 614 2.4E-35 T 30-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 CL1_0151 8807ef07b4bb5fbc86fef58d1d9deb16 634 Gene3D G3DSA:1.10.8.60 320 412 2.8E-44 T 30-10-2018 CL1_0151 8807ef07b4bb5fbc86fef58d1d9deb16 634 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 569 587 1.1E-28 T 30-10-2018 CL1_0151 8807ef07b4bb5fbc86fef58d1d9deb16 634 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 516 535 1.1E-28 T 30-10-2018 CL1_0151 8807ef07b4bb5fbc86fef58d1d9deb16 634 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 546 565 1.1E-28 T 30-10-2018 CL1_0151 8807ef07b4bb5fbc86fef58d1d9deb16 634 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 66 85 1.1E-28 T 30-10-2018 CL1_0151 8807ef07b4bb5fbc86fef58d1d9deb16 634 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 439 455 1.1E-28 T 30-10-2018 CL1_0151 8807ef07b4bb5fbc86fef58d1d9deb16 634 Gene3D G3DSA:3.40.50.300 19 132 6.6E-32 T 30-10-2018 CL1_0151 8807ef07b4bb5fbc86fef58d1d9deb16 634 Gene3D G3DSA:3.40.50.300 161 319 1.5E-43 T 30-10-2018 CL1_1315 bab1468b092b5c217602192b51164c77 338 Gene3D G3DSA:3.40.50.150 150 337 2.8E-33 T 30-10-2018 CL1_1315 bab1468b092b5c217602192b51164c77 338 Gene3D G3DSA:3.30.300.110 64 146 3.3E-12 T 30-10-2018 CL1_1315 bab1468b092b5c217602192b51164c77 338 SUPERFAMILY SSF53335 88 336 9.21E-46 T 30-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CL1_1315 bab1468b092b5c217602192b51164c77 338 Pfam PF02475 Met-10+ like-protein 89 266 5.1E-36 T 30-10-2018 IPR030382 SAM-dependent methyltransferase TRM5/TYW2-type Reactome: R-HSA-6782861 CL1_1739 2633f195087b27495414573343f49c87 605 Gene3D G3DSA:1.50.10.20 31 209 5.8E-7 T 30-10-2018 CL1_1739 2633f195087b27495414573343f49c87 605 SUPERFAMILY SSF48239 268 515 5.65E-14 T 30-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid CL1_1739 2633f195087b27495414573343f49c87 605 SUPERFAMILY SSF48239 462 603 1.55E-15 T 30-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid CL1_1739 2633f195087b27495414573343f49c87 605 Pfam PF00432 Prenyltransferase and squalene oxidase repeat 532 553 4.0 T 30-10-2018 IPR001330 PFTB repeat GO:0003824 CL1_1739 2633f195087b27495414573343f49c87 605 Gene3D G3DSA:1.50.10.20 270 437 2.4E-5 T 30-10-2018 CL1_1739 2633f195087b27495414573343f49c87 605 Gene3D G3DSA:1.50.10.20 453 605 2.1E-11 T 30-10-2018 CL1_1932 4864fb8cf36af2a068e2959122c83e0b 102 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 1 100 24.652 T 30-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_1932 4864fb8cf36af2a068e2959122c83e0b 102 TIGRFAM TIGR01046 uS10_euk_arch: ribosomal protein uS10 2 100 2.6E-50 T 30-10-2018 IPR005729 Ribosomal protein S10, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_1932 4864fb8cf36af2a068e2959122c83e0b 102 SMART SM01403 5 99 7.5E-41 T 30-10-2018 IPR027486 Ribosomal protein S10 domain CL1_1932 4864fb8cf36af2a068e2959122c83e0b 102 Pfam PF00338 Ribosomal protein S10p/S20e 5 98 1.2E-27 T 30-10-2018 IPR027486 Ribosomal protein S10 domain CL1_1932 4864fb8cf36af2a068e2959122c83e0b 102 PRINTS PR00971 Ribosomal protein S10 family signature 3 16 1.6E-16 T 30-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_1932 4864fb8cf36af2a068e2959122c83e0b 102 PRINTS PR00971 Ribosomal protein S10 family signature 60 74 1.6E-16 T 30-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_1932 4864fb8cf36af2a068e2959122c83e0b 102 PRINTS PR00971 Ribosomal protein S10 family signature 38 53 1.6E-16 T 30-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_1932 4864fb8cf36af2a068e2959122c83e0b 102 SUPERFAMILY SSF54999 3 100 4.05E-29 T 30-10-2018 IPR036838 Ribosomal protein S10 domain superfamily CL1_1932 4864fb8cf36af2a068e2959122c83e0b 102 Gene3D G3DSA:3.30.70.600 1 101 5.7E-35 T 30-10-2018 IPR036838 Ribosomal protein S10 domain superfamily CL1_1932 4864fb8cf36af2a068e2959122c83e0b 102 ProSitePatterns PS00361 Ribosomal protein S10 signature. 27 42 - T 30-10-2018 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_1590 3b14bd1bdea963a01bad77cc958d8d6a 836 ProSitePatterns PS00674 AAA-protein family signature. 683 701 - T 30-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 CL1_1590 3b14bd1bdea963a01bad77cc958d8d6a 836 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 583 712 6.5E-48 T 30-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CL1_1590 3b14bd1bdea963a01bad77cc958d8d6a 836 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 248 377 7.6E-51 T 30-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CL1_1590 3b14bd1bdea963a01bad77cc958d8d6a 836 SMART SM00382 579 715 6.1E-24 T 30-10-2018 IPR003593 AAA+ ATPase domain CL1_1590 3b14bd1bdea963a01bad77cc958d8d6a 836 SMART SM00382 244 380 8.2E-26 T 30-10-2018 IPR003593 AAA+ ATPase domain CL1_1590 3b14bd1bdea963a01bad77cc958d8d6a 836 Gene3D G3DSA:3.40.50.300 206 378 9.0E-83 T 30-10-2018 CL1_1590 3b14bd1bdea963a01bad77cc958d8d6a 836 SMART SM01072 116 200 2.3E-17 T 30-10-2018 IPR004201 CDC48, domain 2 CL1_1590 3b14bd1bdea963a01bad77cc958d8d6a 836 Gene3D G3DSA:1.10.8.60 379 399 9.0E-83 T 30-10-2018 CL1_1590 3b14bd1bdea963a01bad77cc958d8d6a 836 TIGRFAM TIGR01243 CDC48: AAA family ATPase, CDC48 subfamily 13 824 0.0 T 30-10-2018 IPR005938 AAA ATPase, CDC48 family GO:0016787 Reactome: R-HSA-110320|Reactome: R-HSA-3371511|Reactome: R-HSA-382556|Reactome: R-HSA-532668|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5678895|Reactome: R-HSA-5689877|Reactome: R-HSA-5689896|Reactome: R-HSA-6798695|Reactome: R-HSA-8866654|Reactome: R-HSA-8876725 CL1_1590 3b14bd1bdea963a01bad77cc958d8d6a 836 Gene3D G3DSA:1.10.8.60 435 534 2.3E-16 T 30-10-2018 CL1_1590 3b14bd1bdea963a01bad77cc958d8d6a 836 SUPERFAMILY SSF50692 11 96 2.15E-27 T 30-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily CL1_1590 3b14bd1bdea963a01bad77cc958d8d6a 836 Pfam PF02359 Cell division protein 48 (CDC48), N-terminal domain 14 98 2.9E-30 T 30-10-2018 IPR003338 CDC48, N-terminal subdomain CL1_1590 3b14bd1bdea963a01bad77cc958d8d6a 836 SUPERFAMILY SSF54585 98 213 5.89E-18 T 30-10-2018 IPR029067 CDC48 domain 2-like superfamily CL1_1590 3b14bd1bdea963a01bad77cc958d8d6a 836 Gene3D G3DSA:3.40.50.300 535 713 8.1E-75 T 30-10-2018 CL1_1590 3b14bd1bdea963a01bad77cc958d8d6a 836 ProSitePatterns PS00674 AAA-protein family signature. 348 366 - T 30-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 CL1_1590 3b14bd1bdea963a01bad77cc958d8d6a 836 SUPERFAMILY SSF52540 540 817 3.53E-79 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_1590 3b14bd1bdea963a01bad77cc958d8d6a 836 SMART SM01073 14 98 9.0E-38 T 30-10-2018 IPR003338 CDC48, N-terminal subdomain CL1_1590 3b14bd1bdea963a01bad77cc958d8d6a 836 SUPERFAMILY SSF52540 206 526 3.28E-68 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_1590 3b14bd1bdea963a01bad77cc958d8d6a 836 Gene3D G3DSA:2.40.40.20 8 98 3.7E-33 T 30-10-2018 CL1_1590 3b14bd1bdea963a01bad77cc958d8d6a 836 Pfam PF02933 Cell division protein 48 (CDC48), domain 2 117 200 4.8E-14 T 30-10-2018 IPR004201 CDC48, domain 2 CL1_1590 3b14bd1bdea963a01bad77cc958d8d6a 836 Gene3D G3DSA:1.10.8.60 714 822 5.3E-31 T 30-10-2018 CL1_0578 919436ce38504ebd7554ac3ec173a078 166 Pfam PF03692 Putative zinc- or iron-chelating domain 25 131 1.3E-19 T 30-10-2018 IPR005358 Putative zinc- or iron-chelating domain containing protein CL1_0263 51ab19de9da2d94c0b36cc91a22af353 285 SUPERFAMILY SSF52768 17 283 1.08E-70 T 30-10-2018 IPR023696 Ureohydrolase domain superfamily CL1_0263 51ab19de9da2d94c0b36cc91a22af353 285 PIRSF PIRSF036979 4 285 1.3E-80 T 30-10-2018 IPR006035 Ureohydrolase GO:0046872 CL1_0263 51ab19de9da2d94c0b36cc91a22af353 285 Pfam PF00491 Arginase family 23 279 1.8E-60 T 30-10-2018 IPR006035 Ureohydrolase GO:0046872 CL1_0263 51ab19de9da2d94c0b36cc91a22af353 285 Gene3D G3DSA:3.40.800.10 5 284 9.3E-74 T 30-10-2018 CL1_0263 51ab19de9da2d94c0b36cc91a22af353 285 TIGRFAM TIGR01230 agmatinase: agmatinase 20 279 2.8E-67 T 30-10-2018 IPR005925 Agmatinase-related KEGG: 00330+3.5.3.11|MetaCyc: PWY-40|MetaCyc: PWY-6305|Reactome: R-HSA-351143 CL1_1631 8fa5cf3e955b8f5eaacfbd4ecc5b877c 449 Pfam PF00574 Clp protease 55 190 5.6E-9 T 30-10-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA CL1_1631 8fa5cf3e955b8f5eaacfbd4ecc5b877c 449 SUPERFAMILY SSF141322 374 443 1.83E-16 T 30-10-2018 CL1_1631 8fa5cf3e955b8f5eaacfbd4ecc5b877c 449 Pfam PF01957 NfeD-like C-terminal, partner-binding 294 442 1.4E-34 T 30-10-2018 IPR002810 NfeD-like, C-terminal domain CL1_1631 8fa5cf3e955b8f5eaacfbd4ecc5b877c 449 Gene3D G3DSA:2.40.50.140 378 449 5.4E-22 T 30-10-2018 CL1_1631 8fa5cf3e955b8f5eaacfbd4ecc5b877c 449 SUPERFAMILY SSF52096 11 190 3.49E-30 T 30-10-2018 IPR029045 ClpP/crotonase-like domain superfamily CL1_1631 8fa5cf3e955b8f5eaacfbd4ecc5b877c 449 Gene3D G3DSA:3.90.226.10 22 244 3.3E-67 T 30-10-2018 CL1_1754 bc2fc4eda6047c87bf6d58f43a749a52 465 Gene3D G3DSA:3.60.21.10 1 280 7.6E-94 T 30-10-2018 IPR029052 Metallo-dependent phosphatase-like CL1_1754 bc2fc4eda6047c87bf6d58f43a749a52 465 SUPERFAMILY SSF56300 1 318 6.84E-51 T 30-10-2018 CL1_1754 bc2fc4eda6047c87bf6d58f43a749a52 465 Gene3D G3DSA:3.30.110.80 234 334 7.6E-94 T 30-10-2018 CL1_1754 bc2fc4eda6047c87bf6d58f43a749a52 465 Pfam PF00149 Calcineurin-like phosphoesterase 1 209 1.7E-14 T 30-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CL1_1754 bc2fc4eda6047c87bf6d58f43a749a52 465 Hamap MF_02044 DNA double-strand break repair protein Mre11 [mre11]. 1 428 22.741 T 30-10-2018 IPR032885 DNA double-strand break repair protein Mre11, archaea-type GO:0006302 CL1_0665 85226bd5a936d49dd7524e41710f6c76 134 Pfam PF04472 Cell division protein SepF 60 132 1.4E-14 T 30-10-2018 IPR007561 Cell division protein SepF/SepF-related GO:0090529 CL1_0665 85226bd5a936d49dd7524e41710f6c76 134 PIRSF PIRSF019313 1 134 4.2E-31 T 30-10-2018 IPR012426 Uncharacterised protein family SepF-related, archaea CL1_0665 85226bd5a936d49dd7524e41710f6c76 134 Gene3D G3DSA:3.30.110.150 50 134 1.8E-25 T 30-10-2018 IPR038594 SepF-like superfamily CL1_1782 84a5a600d8eb8397033bcf0f0517140e 140 Gene3D G3DSA:3.30.1330.80 1 140 1.1E-47 T 30-10-2018 CL1_1782 84a5a600d8eb8397033bcf0f0517140e 140 PIRSF PIRSF016702 1 139 2.8E-43 T 30-10-2018 IPR025707 Predicted DNA-binding protein with PD1-like DNA-binding motif CL1_1782 84a5a600d8eb8397033bcf0f0517140e 140 Pfam PF03479 Domain of unknown function (DUF296) 8 117 7.2E-19 T 30-10-2018 IPR005175 PPC domain CL1_1782 84a5a600d8eb8397033bcf0f0517140e 140 SUPERFAMILY SSF117856 4 129 7.85E-36 T 30-10-2018 CL1_2006 5c76d64a4fd7c4bc64301d4014de7278 427 ProSitePatterns PS00455 Putative AMP-binding domain signature. 81 92 - T 30-10-2018 IPR020845 AMP-binding, conserved site CL1_2006 5c76d64a4fd7c4bc64301d4014de7278 427 Gene3D G3DSA:3.40.50.12780 9 315 1.5E-27 T 30-10-2018 CL1_2006 5c76d64a4fd7c4bc64301d4014de7278 427 SUPERFAMILY SSF56801 65 375 1.7E-25 T 30-10-2018 CL1_2006 5c76d64a4fd7c4bc64301d4014de7278 427 Pfam PF00501 AMP-binding enzyme 74 238 3.4E-12 T 30-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 CL1_1020 ac5c0f00176876ac9358440cd99de72c 163 Gene3D G3DSA:3.10.50.80 2 151 1.2E-55 T 30-10-2018 CL1_1020 ac5c0f00176876ac9358440cd99de72c 163 SUPERFAMILY SSF54534 2 150 4.91E-49 T 30-10-2018 CL1_1020 ac5c0f00176876ac9358440cd99de72c 163 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 3 147 1.1E-22 T 30-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain CL1_1199 92270f12c1ef1660d3f07892f847ff2b 186 TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase 13 174 3.8E-52 T 30-10-2018 IPR004467 Orotate phosphoribosyl transferase domain GO:0004588 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CL1_1199 92270f12c1ef1660d3f07892f847ff2b 186 Pfam PF00156 Phosphoribosyl transferase domain 38 163 1.7E-22 T 30-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CL1_1199 92270f12c1ef1660d3f07892f847ff2b 186 Gene3D G3DSA:3.40.50.2020 1 179 8.5E-61 T 30-10-2018 CL1_1199 92270f12c1ef1660d3f07892f847ff2b 186 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 186 28.626 T 30-10-2018 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CL1_1199 92270f12c1ef1660d3f07892f847ff2b 186 SUPERFAMILY SSF53271 6 163 3.15E-47 T 30-10-2018 IPR029057 Phosphoribosyltransferase-like CL1_0213 ed48a5a42fd0694e1aeff282d66a8bb4 208 Pfam PF00462 Glutaredoxin 81 138 1.4E-6 T 30-10-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 CL1_0213 ed48a5a42fd0694e1aeff282d66a8bb4 208 SUPERFAMILY SSF52833 75 153 2.68E-12 T 30-10-2018 IPR036249 Thioredoxin-like superfamily CL1_0213 ed48a5a42fd0694e1aeff282d66a8bb4 208 Gene3D G3DSA:3.40.30.10 54 164 1.1E-8 T 30-10-2018 CL1_0712 aadd0a8588ca9057def8200d28ceb046 145 SUPERFAMILY SSF46785 4 63 1.89E-15 T 30-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CL1_0712 aadd0a8588ca9057def8200d28ceb046 145 Gene3D G3DSA:1.10.60.10 69 123 6.9E-20 T 30-10-2018 IPR036421 Iron dependent repressor, metal binding and dimerisation domain superfamily GO:0046914|GO:0046983 CL1_0712 aadd0a8588ca9057def8200d28ceb046 145 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 64 129 3.6E-20 T 30-10-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 CL1_0712 aadd0a8588ca9057def8200d28ceb046 145 SMART SM00529 25 124 1.2E-41 T 30-10-2018 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 CL1_0712 aadd0a8588ca9057def8200d28ceb046 145 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 4 58 6.1E-17 T 30-10-2018 IPR022687 DTXR-type HTH domain GO:0003677 CL1_0712 aadd0a8588ca9057def8200d28ceb046 145 Gene3D G3DSA:1.10.10.10 3 68 8.9E-24 T 30-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CL1_0712 aadd0a8588ca9057def8200d28ceb046 145 SUPERFAMILY SSF47979 64 136 2.09E-17 T 30-10-2018 IPR036421 Iron dependent repressor, metal binding and dimerisation domain superfamily GO:0046914|GO:0046983 CL1_0465 4503fd4ef95051aad246d47580daff68 263 SMART SM00382 26 217 4.1E-12 T 30-10-2018 IPR003593 AAA+ ATPase domain CL1_0465 4503fd4ef95051aad246d47580daff68 263 TIGRFAM TIGR01166 cbiO: cobalt ABC transporter, ATP-binding protein 13 194 1.8E-68 T 30-10-2018 IPR005876 Cobalt transport protein ATP-binding subunit GO:0006824 CL1_0465 4503fd4ef95051aad246d47580daff68 263 Gene3D G3DSA:3.40.50.300 1 240 1.3E-70 T 30-10-2018 CL1_0465 4503fd4ef95051aad246d47580daff68 263 SUPERFAMILY SSF52540 1 225 2.47E-63 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_0465 4503fd4ef95051aad246d47580daff68 263 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 30-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CL1_0465 4503fd4ef95051aad246d47580daff68 263 Pfam PF00005 ABC transporter 17 162 1.2E-29 T 30-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CL1_1957 c8fd52eb72f325ce1f5e9d485dd12797 372 TIGRFAM TIGR01899 cas_TM1807_csm5: CRISPR type III-A/MTUBE-associated RAMP protein Csm5 2 368 1.6E-61 T 30-10-2018 IPR010173 CRISPR-associated protein, TM1807 CL1_1957 c8fd52eb72f325ce1f5e9d485dd12797 372 Pfam PF03787 RAMP superfamily 2 317 5.1E-19 T 30-10-2018 IPR005537 CRISPR type III-associated RAMP protein CL1_1225 59d4e9f246eff26abdaa35c4f1945c35 276 SUPERFAMILY SSF103481 179 272 1.57E-6 T 30-10-2018 CL1_1225 59d4e9f246eff26abdaa35c4f1945c35 276 Pfam PF00892 EamA-like transporter family 144 272 6.8E-14 T 30-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CL1_1225 59d4e9f246eff26abdaa35c4f1945c35 276 Pfam PF00892 EamA-like transporter family 6 130 1.1E-18 T 30-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CL1_1225 59d4e9f246eff26abdaa35c4f1945c35 276 SUPERFAMILY SSF103481 38 133 1.01E-14 T 30-10-2018 CL1_0734 b01576360bdcca6ae76441e255babc91 196 SUPERFAMILY SSF53335 4 194 1.8E-34 T 30-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CL1_0734 b01576360bdcca6ae76441e255babc91 196 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 109 115 - T 30-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CL1_0734 b01576360bdcca6ae76441e255babc91 196 Pfam PF05175 Methyltransferase small domain 42 122 7.0E-14 T 30-10-2018 IPR007848 Methyltransferase small domain GO:0008168 CL1_0734 b01576360bdcca6ae76441e255babc91 196 Gene3D G3DSA:3.40.50.150 1 196 7.9E-62 T 30-10-2018 CL1_1620 3eb81ae5555375cae8a4e641415ade5e 280 Gene3D G3DSA:3.40.50.10780 1 217 2.7E-76 T 30-10-2018 IPR027476 D-aminopeptidase, N-terminal CL1_1620 3eb81ae5555375cae8a4e641415ade5e 280 SUPERFAMILY SSF63992 1 275 2.09E-82 T 30-10-2018 IPR036177 Peptidase M55, D-aminopeptidase superfamily CL1_1620 3eb81ae5555375cae8a4e641415ade5e 280 Gene3D G3DSA:3.30.1360.130 118 264 2.7E-76 T 30-10-2018 CL1_1620 3eb81ae5555375cae8a4e641415ade5e 280 Pfam PF04951 D-aminopeptidase 1 265 6.4E-82 T 30-10-2018 IPR007035 Peptidase M55, D-aminopeptidase CL1_1620 3eb81ae5555375cae8a4e641415ade5e 280 PIRSF PIRSF015853 1 277 7.1E-96 T 30-10-2018 IPR007035 Peptidase M55, D-aminopeptidase CL1_1540 582bc51a74f8044e34ca444af2b8544f 250 SUPERFAMILY SSF81301 12 108 8.72E-8 T 30-10-2018 CL1_1540 582bc51a74f8044e34ca444af2b8544f 250 Pfam PF01909 Nucleotidyltransferase domain 10 54 2.6E-6 T 30-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 CL1_1540 582bc51a74f8044e34ca444af2b8544f 250 Gene3D G3DSA:3.30.460.10 6 117 2.6E-10 T 30-10-2018 CL1_0388 a87fed8cfbd82dc3425d4284e02cfef4 396 SUPERFAMILY SSF51905 2 341 3.79E-40 T 30-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily CL1_0388 a87fed8cfbd82dc3425d4284e02cfef4 396 Hamap MF_01287 Digeranylgeranylglycerophospholipid reductase. 4 396 39.538 T 30-10-2018 IPR023590 Digeranylgeranylglycerophospholipid reductase GO:0016628|GO:0045550|GO:0046467|GO:0055114 KEGG: 00564+1.3.7.11|MetaCyc: PWY-6349 CL1_0388 a87fed8cfbd82dc3425d4284e02cfef4 396 Gene3D G3DSA:3.50.50.60 6 341 2.5E-108 T 30-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily CL1_0388 a87fed8cfbd82dc3425d4284e02cfef4 396 Gene3D G3DSA:3.30.9.10 72 359 2.5E-108 T 30-10-2018 CL1_0388 a87fed8cfbd82dc3425d4284e02cfef4 396 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 269 284 4.3E-10 T 30-10-2018 CL1_0388 a87fed8cfbd82dc3425d4284e02cfef4 396 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 7 29 4.3E-10 T 30-10-2018 CL1_0388 a87fed8cfbd82dc3425d4284e02cfef4 396 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 147 162 4.3E-10 T 30-10-2018 CL1_0388 a87fed8cfbd82dc3425d4284e02cfef4 396 TIGRFAM TIGR02032 GG-red-SF: geranylgeranyl reductase family 6 304 1.5E-75 T 30-10-2018 IPR011777 Geranylgeranyl reductase family GO:0016628|GO:0055114 CL1_0388 a87fed8cfbd82dc3425d4284e02cfef4 396 Pfam PF01494 FAD binding domain 6 322 7.8E-14 T 30-10-2018 IPR002938 FAD-binding domain GO:0071949 CL1_1572 a2e8a273ab862ab115fd55a65761048b 51 Hamap MF_00629 50S ribosomal protein L39e [rpl39e]. 1 51 19.1 T 30-10-2018 IPR000077 Ribosomal protein L39e GO:0003735|GO:0005622|GO:0005840|GO:0006412 CL1_1572 a2e8a273ab862ab115fd55a65761048b 51 Pfam PF00832 Ribosomal L39 protein 9 50 3.1E-21 T 30-10-2018 IPR000077 Ribosomal protein L39e GO:0003735|GO:0005622|GO:0005840|GO:0006412 CL1_1572 a2e8a273ab862ab115fd55a65761048b 51 Gene3D G3DSA:1.10.1620.10 2 51 9.7E-19 T 30-10-2018 IPR023626 Ribosomal protein L39e domain superfamily CL1_1572 a2e8a273ab862ab115fd55a65761048b 51 SUPERFAMILY SSF48662 4 50 1.83E-18 T 30-10-2018 IPR023626 Ribosomal protein L39e domain superfamily CL1_0236 14c985123e6d5eef5dd26dd1f1e62f1a 410 Gene3D G3DSA:1.25.40.10 1 346 1.4E-55 T 30-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 CL1_0236 14c985123e6d5eef5dd26dd1f1e62f1a 410 SUPERFAMILY SSF48452 46 132 5.93E-8 T 30-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 CL1_0782 dd26c600c41318d625eff92f252857b3 223 PIRSF PIRSF001586 1 223 2.0E-83 T 30-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CL1_0782 dd26c600c41318d625eff92f252857b3 223 Gene3D G3DSA:3.40.50.880 1 223 4.0E-79 T 30-10-2018 IPR029062 Class I glutamine amidotransferase-like CL1_0782 dd26c600c41318d625eff92f252857b3 223 Hamap MF_00421 Phosphoribosylformylglycinamidine synthase subunit PurQ [purQ]. 2 219 45.058 T 30-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CL1_0782 dd26c600c41318d625eff92f252857b3 223 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 2 220 6.0E-51 T 30-10-2018 CL1_0782 dd26c600c41318d625eff92f252857b3 223 TIGRFAM TIGR01737 FGAM_synth_I: phosphoribosylformylglycinamidine synthase I 2 220 2.6E-96 T 30-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CL1_0782 dd26c600c41318d625eff92f252857b3 223 SMART SM01211 1 221 3.0E-132 T 30-10-2018 CL1_0782 dd26c600c41318d625eff92f252857b3 223 SUPERFAMILY SSF52317 2 221 7.23E-78 T 30-10-2018 IPR029062 Class I glutamine amidotransferase-like CL1_2027 2ee98a84a9b11e66cf8ede42e821d096 372 Gene3D G3DSA:3.40.1280.30 92 234 1.0E-7 T 30-10-2018 IPR038459 tRNA methyltransferase TRM10-type domain superfamily CL1_2027 2ee98a84a9b11e66cf8ede42e821d096 372 PIRSF PIRSF018978 3 372 5.8E-186 T 30-10-2018 IPR016742 tRNA methyltransferase, archaea GO:0008175|GO:0030488 CL1_2027 2ee98a84a9b11e66cf8ede42e821d096 372 Pfam PF04252 Predicted SAM-dependent RNA methyltransferase 177 217 1.1E-4 T 30-10-2018 IPR007364 RNA methyltransferase TK0422/Sfm1 GO:0008168 CL1_0696 dacfbc58da3ec446a6c1bfa40c4becd1 231 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 1 12 3.2E-6 T 30-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 CL1_0696 dacfbc58da3ec446a6c1bfa40c4becd1 231 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 142 158 3.2E-6 T 30-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 CL1_0696 dacfbc58da3ec446a6c1bfa40c4becd1 231 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 160 180 3.2E-6 T 30-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 CL1_0696 dacfbc58da3ec446a6c1bfa40c4becd1 231 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 108 121 3.2E-6 T 30-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 CL1_0696 dacfbc58da3ec446a6c1bfa40c4becd1 231 Gene3D G3DSA:3.40.50.1000 2 215 5.3E-65 T 30-10-2018 IPR023214 HAD superfamily CL1_0696 dacfbc58da3ec446a6c1bfa40c4becd1 231 SUPERFAMILY SSF56784 1 228 8.42E-35 T 30-10-2018 IPR036412 HAD-like superfamily CL1_0696 dacfbc58da3ec446a6c1bfa40c4becd1 231 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 134 199 1.6E-7 T 30-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 CL1_0696 dacfbc58da3ec446a6c1bfa40c4becd1 231 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 135 193 1.8E-6 T 30-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 CL1_0696 dacfbc58da3ec446a6c1bfa40c4becd1 231 Pfam PF13419 Haloacid dehalogenase-like hydrolase 89 199 1.6E-14 T 30-10-2018 CL1_0696 dacfbc58da3ec446a6c1bfa40c4becd1 231 Gene3D G3DSA:1.10.150.400 14 92 5.3E-65 T 30-10-2018 CL1_0713 4bc7876538771d31c5d0c9f760c1f55c 201 Pfam PF04079 Segregation and condensation complex subunit ScpB 9 153 7.2E-36 T 30-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 CL1_0713 4bc7876538771d31c5d0c9f760c1f55c 201 Gene3D G3DSA:1.10.10.10 83 163 1.9E-12 T 30-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CL1_0713 4bc7876538771d31c5d0c9f760c1f55c 201 Gene3D G3DSA:1.10.10.10 2 82 1.9E-11 T 30-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CL1_0713 4bc7876538771d31c5d0c9f760c1f55c 201 TIGRFAM TIGR00281 TIGR00281: segregation and condensation protein B 7 175 1.3E-31 T 30-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 CL1_0713 4bc7876538771d31c5d0c9f760c1f55c 201 SUPERFAMILY SSF46785 85 152 3.39E-15 T 30-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CL1_0713 4bc7876538771d31c5d0c9f760c1f55c 201 PIRSF PIRSF019345 2 198 3.6E-46 T 30-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 CL1_0713 4bc7876538771d31c5d0c9f760c1f55c 201 SUPERFAMILY SSF46785 3 81 1.72E-13 T 30-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CL1_0287 bef61c495167db2b48068c2eb09aabd0 630 SUPERFAMILY SSF55261 278 404 1.55E-45 T 30-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 CL1_0287 bef61c495167db2b48068c2eb09aabd0 630 SMART SM00845 484 624 4.8E-37 T 30-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 CL1_0287 bef61c495167db2b48068c2eb09aabd0 630 TIGRFAM TIGR00134 gatE_arch: glutamyl-tRNA(Gln) amidotransferase, subunit E 5 626 4.2E-240 T 30-10-2018 IPR004414 Glutamyl-tRNA(Gln) amidotransferase subunit E GO:0016884 CL1_0287 bef61c495167db2b48068c2eb09aabd0 630 Gene3D G3DSA:1.10.150.380 453 546 7.6E-25 T 30-10-2018 CL1_0287 bef61c495167db2b48068c2eb09aabd0 630 Pfam PF02934 GatB/GatE catalytic domain 13 444 7.3E-66 T 30-10-2018 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 CL1_0287 bef61c495167db2b48068c2eb09aabd0 630 SUPERFAMILY SSF55931 4 453 1.05E-100 T 30-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 CL1_0287 bef61c495167db2b48068c2eb09aabd0 630 ProDom PD609240 SUBUNIT E AMIDOTRANSFERASE 6.3.5.- LIGASE GLUTAMYL-TRNAGLN GLU-ADT BIOSYNTHESIS TRANSFERASE B 282 406 1.0E-59 T 30-10-2018 CL1_0287 bef61c495167db2b48068c2eb09aabd0 630 Gene3D G3DSA:3.30.1360.30 274 404 3.5E-52 T 30-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 CL1_0287 bef61c495167db2b48068c2eb09aabd0 630 SUPERFAMILY SSF89095 482 624 1.57E-28 T 30-10-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-like GO:0016884 CL1_0287 bef61c495167db2b48068c2eb09aabd0 630 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 177 191 - T 30-10-2018 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 CL1_0287 bef61c495167db2b48068c2eb09aabd0 630 Gene3D G3DSA:1.10.10.410 566 624 2.5E-13 T 30-10-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal CL1_0287 bef61c495167db2b48068c2eb09aabd0 630 Hamap MF_00588 Glutamyl-tRNA(Gln) amidotransferase subunit E [gatE]. 1 630 338.047 T 30-10-2018 IPR004414 Glutamyl-tRNA(Gln) amidotransferase subunit E GO:0016884 CL1_0287 bef61c495167db2b48068c2eb09aabd0 630 Pfam PF02637 GatB domain 485 624 1.5E-28 T 30-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 CL1_0287 bef61c495167db2b48068c2eb09aabd0 630 Pfam PF02938 GAD domain 299 390 6.3E-17 T 30-10-2018 IPR029351 GAD domain Reactome: R-HSA-379726 CL1_0604 68d09cf54d14e1f6df0d214a4d741101 481 Pfam PF00344 SecY translocase 72 460 3.5E-70 T 30-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CL1_0604 68d09cf54d14e1f6df0d214a4d741101 481 Gene3D G3DSA:1.10.3370.10 26 481 1.9E-177 T 30-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CL1_0604 68d09cf54d14e1f6df0d214a4d741101 481 SUPERFAMILY SSF103491 9 467 1.44E-109 T 30-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CL1_0604 68d09cf54d14e1f6df0d214a4d741101 481 Pfam PF10559 Plug domain of Sec61p 38 71 2.8E-11 T 30-10-2018 IPR019561 Translocon Sec61/SecY, plug domain Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CL1_0604 68d09cf54d14e1f6df0d214a4d741101 481 PRINTS PR00303 Preprotein translocase SecY subunit signature 159 184 7.1E-8 T 30-10-2018 CL1_0604 68d09cf54d14e1f6df0d214a4d741101 481 PRINTS PR00303 Preprotein translocase SecY subunit signature 30 48 7.1E-8 T 30-10-2018 CL1_0604 68d09cf54d14e1f6df0d214a4d741101 481 PRINTS PR00303 Preprotein translocase SecY subunit signature 445 463 7.1E-8 T 30-10-2018 CL1_0604 68d09cf54d14e1f6df0d214a4d741101 481 PRINTS PR00303 Preprotein translocase SecY subunit signature 185 208 7.1E-8 T 30-10-2018 CL1_0604 68d09cf54d14e1f6df0d214a4d741101 481 Hamap MF_01465 Protein translocase subunit SecY [secY]. 17 476 20.558 T 30-10-2018 IPR026593 Protein translocase subunit SecY CL1_0604 68d09cf54d14e1f6df0d214a4d741101 481 ProSitePatterns PS00756 Protein secY signature 2. 178 195 - T 30-10-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CL1_0604 68d09cf54d14e1f6df0d214a4d741101 481 PIRSF PIRSF004557 5 481 1.1E-102 T 30-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CL1_0604 68d09cf54d14e1f6df0d214a4d741101 481 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 27 469 1.1E-91 T 30-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CL1_0604 68d09cf54d14e1f6df0d214a4d741101 481 ProSitePatterns PS00755 Protein secY signature 1. 72 91 - T 30-10-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CL1_1072 31688398e690a8073eedecd881690887 148 ProDom PD020174 PH0907 MJECS03 PLASMID PF0569 AF2351 40 145 1.0E-35 T 30-10-2018 IPR007176 Protein of unknown function DUF365 CL1_1072 31688398e690a8073eedecd881690887 148 PIRSF PIRSF006031 3 146 7.3E-65 T 30-10-2018 IPR007176 Protein of unknown function DUF365 CL1_1072 31688398e690a8073eedecd881690887 148 Pfam PF04033 Domain of unknown function (DUF365) 40 135 5.3E-36 T 30-10-2018 IPR007176 Protein of unknown function DUF365 CL1_1072 31688398e690a8073eedecd881690887 148 Gene3D G3DSA:2.30.130.30 1 136 9.7E-53 T 30-10-2018 CL1_1215 eb0adac1ea6af58fb4cabf1422e2770b 220 Gene3D G3DSA:3.40.50.300 1 219 5.0E-53 T 30-10-2018 CL1_1215 eb0adac1ea6af58fb4cabf1422e2770b 220 Pfam PF00005 ABC transporter 18 155 4.4E-22 T 30-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CL1_1215 eb0adac1ea6af58fb4cabf1422e2770b 220 SMART SM00382 25 211 1.9E-7 T 30-10-2018 IPR003593 AAA+ ATPase domain CL1_1215 eb0adac1ea6af58fb4cabf1422e2770b 220 ProSitePatterns PS00211 ABC transporters family signature. 127 141 - T 30-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CL1_1215 eb0adac1ea6af58fb4cabf1422e2770b 220 SUPERFAMILY SSF52540 2 215 1.1E-50 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_1252 262eb39283588aa790adba485ca34b08 119 Pfam PF02627 Carboxymuconolactone decarboxylase family 30 106 7.6E-19 T 30-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CL1_1252 262eb39283588aa790adba485ca34b08 119 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 43 87 2.4E-13 T 30-10-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CL1_1252 262eb39283588aa790adba485ca34b08 119 SUPERFAMILY SSF69118 9 109 3.53E-27 T 30-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CL1_1252 262eb39283588aa790adba485ca34b08 119 Gene3D G3DSA:1.20.1290.10 3 119 8.1E-30 T 30-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CL1_1366 4ea4a07b12b236db9023534c790072f2 481 Gene3D G3DSA:3.10.20.440 5 100 5.5E-34 T 30-10-2018 CL1_1366 4ea4a07b12b236db9023534c790072f2 481 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 15 95 1.3E-28 T 30-10-2018 CL1_1366 4ea4a07b12b236db9023534c790072f2 481 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 225 243 1.1E-25 T 30-10-2018 CL1_1366 4ea4a07b12b236db9023534c790072f2 481 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 269 287 1.1E-25 T 30-10-2018 CL1_1366 4ea4a07b12b236db9023534c790072f2 481 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 359 375 1.1E-25 T 30-10-2018 CL1_1366 4ea4a07b12b236db9023534c790072f2 481 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 391 413 1.1E-25 T 30-10-2018 CL1_1366 4ea4a07b12b236db9023534c790072f2 481 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 119 138 1.1E-25 T 30-10-2018 CL1_1366 4ea4a07b12b236db9023534c790072f2 481 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 60 68 - T 30-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CL1_1366 4ea4a07b12b236db9023534c790072f2 481 SUPERFAMILY SSF54292 17 102 1.05E-21 T 30-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 CL1_1366 4ea4a07b12b236db9023534c790072f2 481 SUPERFAMILY SSF51905 107 432 4.49E-41 T 30-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily CL1_1366 4ea4a07b12b236db9023534c790072f2 481 Gene3D G3DSA:3.50.50.60 118 442 1.2E-58 T 30-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily CL1_1366 4ea4a07b12b236db9023534c790072f2 481 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 228 237 1.3E-21 T 30-10-2018 CL1_1366 4ea4a07b12b236db9023534c790072f2 481 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 406 413 1.3E-21 T 30-10-2018 CL1_1366 4ea4a07b12b236db9023534c790072f2 481 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 269 294 1.3E-21 T 30-10-2018 CL1_1366 4ea4a07b12b236db9023534c790072f2 481 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 360 374 1.3E-21 T 30-10-2018 CL1_1366 4ea4a07b12b236db9023534c790072f2 481 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 118 140 1.3E-21 T 30-10-2018 CL1_1366 4ea4a07b12b236db9023534c790072f2 481 Gene3D G3DSA:3.50.50.60 237 367 1.2E-58 T 30-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily CL1_1366 4ea4a07b12b236db9023534c790072f2 481 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 118 425 5.7E-38 T 30-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CL1_0495 682c317559ed37abb03e69c2b341f8b0 316 SMART SM00729 15 227 0.0015 T 30-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 CL1_0495 682c317559ed37abb03e69c2b341f8b0 316 Pfam PF04055 Radical SAM superfamily 25 191 6.5E-14 T 30-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CL1_0495 682c317559ed37abb03e69c2b341f8b0 316 SUPERFAMILY SSF102114 25 227 2.75E-20 T 30-10-2018 CL1_0495 682c317559ed37abb03e69c2b341f8b0 316 Gene3D G3DSA:3.20.20.70 20 263 8.7E-17 T 30-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CL1_0355 83698ef213e15764daab1cc52630b9c9 415 Gene3D G3DSA:3.30.70.3160 44 125 1.0E-115 T 30-10-2018 CL1_0355 83698ef213e15764daab1cc52630b9c9 415 Pfam PF01142 tRNA pseudouridine synthase D (TruD) 13 411 3.4E-131 T 30-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 CL1_0355 83698ef213e15764daab1cc52630b9c9 415 TIGRFAM TIGR00094 tRNA_TruD_broad: tRNA pseudouridine synthase, TruD family 10 414 1.2E-83 T 30-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 CL1_0355 83698ef213e15764daab1cc52630b9c9 415 SUPERFAMILY SSF55120 7 413 2.73E-93 T 30-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 CL1_0355 83698ef213e15764daab1cc52630b9c9 415 PIRSF PIRSF037016 38 390 1.4E-63 T 30-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 CL1_0355 83698ef213e15764daab1cc52630b9c9 415 PIRSF PIRSF037016 388 415 0.016 T 30-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 CL1_0355 83698ef213e15764daab1cc52630b9c9 415 ProSitePatterns PS01268 Uncharacterized protein family UPF0024 signature. 80 93 - T 30-10-2018 IPR020119 Pseudouridine synthase TruD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 Reactome: R-HSA-6782315 CL1_0355 83698ef213e15764daab1cc52630b9c9 415 Gene3D G3DSA:3.30.2350.20 126 410 1.0E-115 T 30-10-2018 CL1_0355 83698ef213e15764daab1cc52630b9c9 415 Hamap MF_01082 tRNA pseudouridine synthase D [truD]. 8 415 29.63 T 30-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 CL1_0355 83698ef213e15764daab1cc52630b9c9 415 Gene3D G3DSA:1.10.1510.30 171 256 1.0E-115 T 30-10-2018 CL1_0379 b418c5a31e87d09b264dba863a9a15d6 725 Gene3D G3DSA:1.10.3210.30 5 143 4.6E-16 T 30-10-2018 IPR038257 CRISPR-associated Cas3-type HD domain superfamily CL1_0379 b418c5a31e87d09b264dba863a9a15d6 725 TIGRFAM TIGR01587 cas3_core: CRISPR-associated helicase Cas3 245 585 2.8E-102 T 30-10-2018 IPR006474 Helicase Cas3, CRISPR-associated, core CL1_0379 b418c5a31e87d09b264dba863a9a15d6 725 SUPERFAMILY SSF109604 48 174 1.47E-6 T 30-10-2018 CL1_0379 b418c5a31e87d09b264dba863a9a15d6 725 SMART SM00490 471 550 2.0E-9 T 30-10-2018 IPR001650 Helicase, C-terminal CL1_0379 b418c5a31e87d09b264dba863a9a15d6 725 Gene3D G3DSA:3.40.50.300 415 587 9.9E-18 T 30-10-2018 CL1_0379 b418c5a31e87d09b264dba863a9a15d6 725 Gene3D G3DSA:3.40.50.300 219 414 1.6E-15 T 30-10-2018 CL1_0379 b418c5a31e87d09b264dba863a9a15d6 725 Pfam PF00271 Helicase conserved C-terminal domain 446 550 4.4E-9 T 30-10-2018 IPR001650 Helicase, C-terminal CL1_0379 b418c5a31e87d09b264dba863a9a15d6 725 TIGRFAM TIGR01596 cas3_HD: CRISPR-associated endonuclease Cas3-HD 14 207 8.9E-29 T 30-10-2018 IPR006483 CRISPR-associated Cas3-type HD domain CL1_0379 b418c5a31e87d09b264dba863a9a15d6 725 SMART SM00487 227 439 1.6E-11 T 30-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CL1_0379 b418c5a31e87d09b264dba863a9a15d6 725 Pfam PF00270 DEAD/DEAH box helicase 241 409 9.8E-11 T 30-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CL1_0379 b418c5a31e87d09b264dba863a9a15d6 725 SUPERFAMILY SSF52540 238 560 3.66E-36 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_0284 ae467d028309107c242a23ddf2a7f63d 386 Gene3D G3DSA:3.30.70.3190 276 384 2.6E-29 T 30-10-2018 CL1_0284 ae467d028309107c242a23ddf2a7f63d 386 SUPERFAMILY SSF55120 271 383 5.04E-13 T 30-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 CL1_0284 ae467d028309107c242a23ddf2a7f63d 386 Hamap MF_01893 tRNA pseudouridine synthase Pus10 [pus10]. 7 385 51.453 T 30-10-2018 IPR005912 tRNA pseudouridine synthase, Pus10 GO:0000049|GO:0001522|GO:0006400|GO:0009982 CL1_0284 ae467d028309107c242a23ddf2a7f63d 386 Pfam PF02926 THUMP domain 55 162 6.3E-9 T 30-10-2018 IPR004114 THUMP domain GO:0003723 CL1_0284 ae467d028309107c242a23ddf2a7f63d 386 Gene3D G3DSA:3.30.70.2510 162 275 4.1E-27 T 30-10-2018 CL1_0284 ae467d028309107c242a23ddf2a7f63d 386 TIGRFAM TIGR01213 pseudo_Pus10arc: tRNA pseudouridine(54/55) synthase 8 385 1.1E-142 T 30-10-2018 IPR005912 tRNA pseudouridine synthase, Pus10 GO:0000049|GO:0001522|GO:0006400|GO:0009982 CL1_0235 b2887bdfa3fa52fa192abb53a32cb900 108 Gene3D G3DSA:1.10.10.1220 1 88 8.2E-46 T 30-10-2018 CL1_0765 613fb2fba04ef35de1ed6ced014d9343 333 Hamap MF_01921 S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase [taw1]. 15 316 49.35 T 30-10-2018 IPR023993 S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase, archaea GO:0008033|GO:0016829|GO:0051539 MetaCyc: PWY-7285|MetaCyc: PWY-7286 CL1_0765 613fb2fba04ef35de1ed6ced014d9343 333 Pfam PF04055 Radical SAM superfamily 67 252 1.5E-24 T 30-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CL1_0765 613fb2fba04ef35de1ed6ced014d9343 333 Gene3D G3DSA:3.20.20.70 2 333 2.4E-132 T 30-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CL1_0765 613fb2fba04ef35de1ed6ced014d9343 333 SUPERFAMILY SSF102114 67 273 6.47E-18 T 30-10-2018 CL1_0765 613fb2fba04ef35de1ed6ced014d9343 333 Pfam PF08608 Wyosine base formation 255 315 4.3E-21 T 30-10-2018 IPR013917 tRNA wybutosine-synthesis MetaCyc: PWY-7285|MetaCyc: PWY-7286 CL1_0765 613fb2fba04ef35de1ed6ced014d9343 333 TIGRFAM TIGR03972 rSAM_TYW1: wyosine biosynthesis protein TYW1 17 314 9.5E-129 T 30-10-2018 IPR023993 S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase, archaea GO:0008033|GO:0016829|GO:0051539 MetaCyc: PWY-7285|MetaCyc: PWY-7286 CL1_1864 368f57fe641bb9773e40bdd10caf474a 189 Gene3D G3DSA:3.40.5.50 134 188 2.4E-25 T 30-10-2018 CL1_1864 368f57fe641bb9773e40bdd10caf474a 189 Gene3D G3DSA:1.20.58.1030 1 113 2.4E-46 T 30-10-2018 CL1_0449 b26e6fe90e0ff69fa74a356e5caaafc8 67 SUPERFAMILY SSF54285 3 67 1.89E-11 T 30-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp CL1_0449 b26e6fe90e0ff69fa74a356e5caaafc8 67 Gene3D G3DSA:3.10.20.30 1 67 1.4E-23 T 30-10-2018 IPR012675 Beta-grasp domain superfamily CL1_0449 b26e6fe90e0ff69fa74a356e5caaafc8 67 Pfam PF02597 ThiS family 10 67 7.8E-10 T 30-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 CL1_0588 7e97a8876c40b3d956bcb51bdb5ccb0a 57 SUPERFAMILY SSF63562 3 55 1.44E-20 T 30-10-2018 IPR036161 RPB6/omega subunit-like superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 CL1_0588 7e97a8876c40b3d956bcb51bdb5ccb0a 57 ProSitePatterns PS01111 RNA polymerases K / 14 to 18 Kd subunits signature. 5 19 - T 30-10-2018 IPR020708 DNA-directed RNA polymerase, 14-18kDa subunit, conserved site GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 CL1_0588 7e97a8876c40b3d956bcb51bdb5ccb0a 57 Gene3D G3DSA:3.90.940.50 1 57 2.9E-28 T 30-10-2018 CL1_0588 7e97a8876c40b3d956bcb51bdb5ccb0a 57 PIRSF PIRSF000778 1 57 3.0E-23 T 30-10-2018 IPR006111 Archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 CL1_0588 7e97a8876c40b3d956bcb51bdb5ccb0a 57 Pfam PF01192 RNA polymerase Rpb6 5 51 1.1E-11 T 30-10-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 CL1_0588 7e97a8876c40b3d956bcb51bdb5ccb0a 57 Hamap MF_00192 DNA-directed RNA polymerase subunit K [rpoK]. 2 57 22.095 T 30-10-2018 IPR006111 Archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 CL1_1742 c60d27a90c025e1c63cb9fce06848ca4 70 Hamap MF_00292 30S ribosomal protein S28e [rps28e]. 1 67 24.283 T 30-10-2018 IPR000289 Ribosomal protein S28e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_1742 c60d27a90c025e1c63cb9fce06848ca4 70 Pfam PF01200 Ribosomal protein S28e 4 66 9.1E-28 T 30-10-2018 IPR000289 Ribosomal protein S28e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_1742 c60d27a90c025e1c63cb9fce06848ca4 70 ProSitePatterns PS00961 Ribosomal protein S28e signature. 58 66 - T 30-10-2018 IPR028626 Ribosomal protein S28e conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_1742 c60d27a90c025e1c63cb9fce06848ca4 70 SUPERFAMILY SSF50249 3 69 2.57E-23 T 30-10-2018 IPR012340 Nucleic acid-binding, OB-fold CL1_1742 c60d27a90c025e1c63cb9fce06848ca4 70 Gene3D G3DSA:2.40.50.140 1 70 3.8E-31 T 30-10-2018 CL1_1742 c60d27a90c025e1c63cb9fce06848ca4 70 ProDom PD005541 RIBOSOMAL RIBONUCLEOPROTEIN 40S S28 S28E 30S ACETYLATION S33 S33 CG15527 1 48 4.0E-18 T 30-10-2018 IPR000289 Ribosomal protein S28e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0784 c44a06f857660ee83d7f08cef9902dc9 380 SUPERFAMILY SSF52440 1 133 2.01E-40 T 30-10-2018 IPR016185 Pre-ATP-grasp domain superfamily CL1_0784 c44a06f857660ee83d7f08cef9902dc9 380 Pfam PF06849 Protein of unknown function (DUF1246) 21 153 7.4E-42 T 30-10-2018 IPR010672 IMP biosynthesis enzyme PurP, N-terminal GO:0000287|GO:0005524|GO:0006188|GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 CL1_0784 c44a06f857660ee83d7f08cef9902dc9 380 SUPERFAMILY SSF56059 139 380 7.36E-76 T 30-10-2018 CL1_0784 c44a06f857660ee83d7f08cef9902dc9 380 Gene3D G3DSA:3.40.50.20 1 121 3.4E-42 T 30-10-2018 CL1_0784 c44a06f857660ee83d7f08cef9902dc9 380 Gene3D G3DSA:3.30.1490.20 152 218 1.8E-91 T 30-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 CL1_0784 c44a06f857660ee83d7f08cef9902dc9 380 PIRSF PIRSF004602 1 380 3.7E-140 T 30-10-2018 IPR023656 IMP biosynthesis enzyme PurP GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 CL1_0784 c44a06f857660ee83d7f08cef9902dc9 380 Pfam PF06973 Domain of unknown function (DUF1297) 189 380 6.8E-80 T 30-10-2018 IPR009720 IMP biosynthesis enzyme PurP, C-terminal GO:0000287|GO:0005524|GO:0006188|GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 CL1_0784 c44a06f857660ee83d7f08cef9902dc9 380 Gene3D G3DSA:3.30.470.20 122 379 1.8E-91 T 30-10-2018 CL1_1971 8edfe0004cc32f7875e163df906272a4 222 Pfam PF00535 Glycosyl transferase family 2 8 167 1.7E-39 T 30-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CL1_1971 8edfe0004cc32f7875e163df906272a4 222 SUPERFAMILY SSF53448 5 221 7.04E-54 T 30-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases CL1_1971 8edfe0004cc32f7875e163df906272a4 222 Gene3D G3DSA:3.90.550.10 3 222 5.5E-63 T 30-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases CL1_1244 cdc9c5d28e90e028ea89e559529ce7c3 394 Gene3D G3DSA:3.40.50.970 1 252 2.3E-104 T 30-10-2018 CL1_1244 cdc9c5d28e90e028ea89e559529ce7c3 394 SUPERFAMILY SSF52922 254 369 1.86E-31 T 30-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 CL1_1244 cdc9c5d28e90e028ea89e559529ce7c3 394 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 262 365 4.7E-28 T 30-10-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II CL1_1244 cdc9c5d28e90e028ea89e559529ce7c3 394 SUPERFAMILY SSF52518 4 251 1.5E-69 T 30-10-2018 IPR029061 Thiamin diphosphate-binding fold CL1_1244 cdc9c5d28e90e028ea89e559529ce7c3 394 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 16 240 1.6E-80 T 30-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 CL1_1244 cdc9c5d28e90e028ea89e559529ce7c3 394 Gene3D G3DSA:3.40.50.920 253 391 2.7E-39 T 30-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 CL1_0109 a6a20b8253461389c4339969b2b42516 413 Gene3D G3DSA:3.90.550.10 1 238 8.9E-74 T 30-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases CL1_0109 a6a20b8253461389c4339969b2b42516 413 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 313 346 1.3E-4 T 30-10-2018 IPR001451 Hexapeptide repeat CL1_0109 a6a20b8253461389c4339969b2b42516 413 SUPERFAMILY SSF53448 1 299 2.58E-74 T 30-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases CL1_0109 a6a20b8253461389c4339969b2b42516 413 Pfam PF00483 Nucleotidyl transferase 2 230 2.2E-45 T 30-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 CL1_0109 a6a20b8253461389c4339969b2b42516 413 Gene3D G3DSA:2.160.10.10 239 370 2.2E-18 T 30-10-2018 CL1_0684 7eaa506f85884d816d62add73fbd4f73 181 Pfam PF00857 Isochorismatase family 5 179 2.9E-45 T 30-10-2018 IPR000868 Isochorismatase-like GO:0003824 CL1_0684 7eaa506f85884d816d62add73fbd4f73 181 SUPERFAMILY SSF52499 4 179 3.01E-55 T 30-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 CL1_0684 7eaa506f85884d816d62add73fbd4f73 181 Gene3D G3DSA:3.40.50.850 1 179 4.2E-72 T 30-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 CL1_1863 de0191a3c9aaabfb8f21bb2452805968 636 Gene3D G3DSA:3.30.2070.10 407 487 1.4E-123 T 30-10-2018 CL1_1863 de0191a3c9aaabfb8f21bb2452805968 636 Gene3D G3DSA:3.40.228.10 133 505 1.4E-123 T 30-10-2018 CL1_1863 de0191a3c9aaabfb8f21bb2452805968 636 Gene3D G3DSA:2.20.25.90 2 58 1.7E-10 T 30-10-2018 CL1_1863 de0191a3c9aaabfb8f21bb2452805968 636 SMART SM00926 1 53 2.1E-9 T 30-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CL1_1863 de0191a3c9aaabfb8f21bb2452805968 636 SUPERFAMILY SSF53706 4 525 6.15E-140 T 30-10-2018 CL1_1863 de0191a3c9aaabfb8f21bb2452805968 636 Gene3D G3DSA:3.40.50.740 67 450 1.4E-123 T 30-10-2018 CL1_1863 de0191a3c9aaabfb8f21bb2452805968 636 Pfam PF00384 Molybdopterin oxidoreductase 56 428 4.7E-48 T 30-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CL1_1863 de0191a3c9aaabfb8f21bb2452805968 636 Gene3D G3DSA:2.40.40.20 517 636 2.2E-29 T 30-10-2018 CL1_1863 de0191a3c9aaabfb8f21bb2452805968 636 ProSitePatterns PS00932 Prokaryotic molybdopterin oxidoreductases signature 3. 558 585 - T 30-10-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 CL1_1863 de0191a3c9aaabfb8f21bb2452805968 636 Pfam PF01568 Molydopterin dinucleotide binding domain 526 629 3.4E-20 T 30-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 CL1_1863 de0191a3c9aaabfb8f21bb2452805968 636 SUPERFAMILY SSF50692 516 636 1.31E-32 T 30-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily CL1_1863 de0191a3c9aaabfb8f21bb2452805968 636 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 4 47 7.0E-8 T 30-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CL1_0992 55ab930e87fdcbeb48fa20d6b44d4fd4 321 SUPERFAMILY SSF52540 26 295 3.44E-19 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_0992 55ab930e87fdcbeb48fa20d6b44d4fd4 321 Gene3D G3DSA:3.40.50.300 29 106 5.8E-6 T 30-10-2018 CL1_0992 55ab930e87fdcbeb48fa20d6b44d4fd4 321 Gene3D G3DSA:3.40.50.300 124 298 4.0E-6 T 30-10-2018 CL1_1823 30749916cca82bd5818a8c6acd7b4999 252 Hamap MF_01013 Imidazole glycerol phosphate synthase subunit HisF [hisF]. 1 249 47.664 T 30-10-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 CL1_1823 30749916cca82bd5818a8c6acd7b4999 252 Pfam PF00977 Histidine biosynthesis protein 5 233 6.4E-88 T 30-10-2018 IPR006062 Histidine biosynthesis GO:0000105 CL1_1823 30749916cca82bd5818a8c6acd7b4999 252 Gene3D G3DSA:3.20.20.70 1 252 2.4E-106 T 30-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CL1_1823 30749916cca82bd5818a8c6acd7b4999 252 TIGRFAM TIGR00735 hisF: imidazoleglycerol phosphate synthase, cyclase subunit 1 249 4.1E-108 T 30-10-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 CL1_1823 30749916cca82bd5818a8c6acd7b4999 252 SUPERFAMILY SSF51366 1 249 2.43E-83 T 30-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 CL1_1834 c451778d02dd47d45810eb44bf9fbe13 230 Pfam PF00005 ABC transporter 21 158 2.3E-20 T 30-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CL1_1834 c451778d02dd47d45810eb44bf9fbe13 230 ProSitePatterns PS00211 ABC transporters family signature. 130 144 - T 30-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CL1_1834 c451778d02dd47d45810eb44bf9fbe13 230 SMART SM00382 28 214 5.7E-4 T 30-10-2018 IPR003593 AAA+ ATPase domain CL1_1834 c451778d02dd47d45810eb44bf9fbe13 230 SUPERFAMILY SSF52540 4 220 3.66E-47 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_1834 c451778d02dd47d45810eb44bf9fbe13 230 Gene3D G3DSA:3.40.50.300 1 223 1.9E-47 T 30-10-2018 CL1_1161 db609a889e3e771596289769b6ca6458 325 Pfam PF00005 ABC transporter 40 186 6.2E-26 T 30-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CL1_1161 db609a889e3e771596289769b6ca6458 325 SMART SM00382 47 236 7.2E-12 T 30-10-2018 IPR003593 AAA+ ATPase domain CL1_1161 db609a889e3e771596289769b6ca6458 325 Gene3D G3DSA:3.40.50.300 23 259 1.4E-53 T 30-10-2018 CL1_1161 db609a889e3e771596289769b6ca6458 325 SUPERFAMILY SSF52540 30 247 6.68E-52 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_1865 5dcf855c1e74c9b662a44259dc3460b7 249 Pfam PF02747 Proliferating cell nuclear antigen, C-terminal domain 126 245 4.3E-10 T 30-10-2018 IPR022649 Proliferating cell nuclear antigen, PCNA, C-terminal GO:0003677|GO:0006275 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 CL1_1865 5dcf855c1e74c9b662a44259dc3460b7 249 SUPERFAMILY SSF55979 125 247 2.24E-31 T 30-10-2018 CL1_1865 5dcf855c1e74c9b662a44259dc3460b7 249 ProSitePatterns PS01251 Proliferating cell nuclear antigen signature 1. 35 58 - T 30-10-2018 IPR022659 Proliferating cell nuclear antigen, PCNA, conserved site Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 CL1_1865 5dcf855c1e74c9b662a44259dc3460b7 249 SUPERFAMILY SSF55979 3 117 7.4E-34 T 30-10-2018 CL1_1865 5dcf855c1e74c9b662a44259dc3460b7 249 Gene3D G3DSA:3.70.10.10 2 242 1.2E-79 T 30-10-2018 CL1_1865 5dcf855c1e74c9b662a44259dc3460b7 249 Pfam PF00705 Proliferating cell nuclear antigen, N-terminal domain 4 117 2.0E-18 T 30-10-2018 IPR022648 Proliferating cell nuclear antigen, PCNA, N-terminal GO:0003677|GO:0006275 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 CL1_1865 5dcf855c1e74c9b662a44259dc3460b7 249 TIGRFAM TIGR00590 pcna: proliferating cell nuclear antigen (pcna) 3 249 6.2E-40 T 30-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 CL1_1865 5dcf855c1e74c9b662a44259dc3460b7 249 Hamap MF_00317 DNA polymerase sliding clamp [pcn]. 3 247 32.865 T 30-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 CL1_1865 5dcf855c1e74c9b662a44259dc3460b7 249 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 35 53 3.5E-15 T 30-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 CL1_1865 5dcf855c1e74c9b662a44259dc3460b7 249 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 57 81 3.5E-15 T 30-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 CL1_1865 5dcf855c1e74c9b662a44259dc3460b7 249 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 107 129 3.5E-15 T 30-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 CL1_1865 5dcf855c1e74c9b662a44259dc3460b7 249 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 195 209 3.5E-15 T 30-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 CL1_1865 5dcf855c1e74c9b662a44259dc3460b7 249 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 233 249 3.5E-15 T 30-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 CL1_0709 438a02603643d079917290a9ace82ee6 334 Gene3D G3DSA:3.40.50.300 3 236 2.9E-74 T 30-10-2018 CL1_0709 438a02603643d079917290a9ace82ee6 334 Pfam PF00005 ABC transporter 22 160 4.5E-34 T 30-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CL1_0709 438a02603643d079917290a9ace82ee6 334 SUPERFAMILY SSF52540 4 241 1.01E-87 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_0709 438a02603643d079917290a9ace82ee6 334 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 30-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CL1_0709 438a02603643d079917290a9ace82ee6 334 SMART SM00382 27 210 1.0E-17 T 30-10-2018 IPR003593 AAA+ ATPase domain CL1_0709 438a02603643d079917290a9ace82ee6 334 SUPERFAMILY SSF50331 237 315 3.8E-5 T 30-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal CL1_1380 623b8f4ff52b11041cfd6f20216e9734 386 SUPERFAMILY SSF54373 224 316 1.02E-9 T 30-10-2018 CL1_1380 623b8f4ff52b11041cfd6f20216e9734 386 Gene3D G3DSA:3.50.50.60 12 359 1.3E-142 T 30-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily CL1_1380 623b8f4ff52b11041cfd6f20216e9734 386 Pfam PF01266 FAD dependent oxidoreductase 11 355 2.4E-74 T 30-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CL1_1380 623b8f4ff52b11041cfd6f20216e9734 386 Gene3D G3DSA:3.30.9.10 88 315 1.3E-142 T 30-10-2018 CL1_1380 623b8f4ff52b11041cfd6f20216e9734 386 SUPERFAMILY SSF51905 10 377 9.06E-62 T 30-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily CL1_0576 dc39fe66d8bf3202f162c8c6b3073919 448 SUPERFAMILY SSF52540 96 297 2.39E-49 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_0576 dc39fe66d8bf3202f162c8c6b3073919 448 Gene3D G3DSA:1.10.260.30 312 435 1.1E-45 T 30-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 CL1_0576 dc39fe66d8bf3202f162c8c6b3073919 448 Gene3D G3DSA:3.40.50.300 91 284 4.7E-122 T 30-10-2018 CL1_0576 dc39fe66d8bf3202f162c8c6b3073919 448 SUPERFAMILY SSF47364 1 94 2.36E-23 T 30-10-2018 IPR036225 SRP/SRP receptor, N-terminal Reactome: R-HSA-1799339 CL1_0576 dc39fe66d8bf3202f162c8c6b3073919 448 Pfam PF00448 SRP54-type protein, GTPase domain 100 295 3.1E-74 T 30-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CL1_0576 dc39fe66d8bf3202f162c8c6b3073919 448 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 6 438 38.037 T 30-10-2018 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 CL1_0576 dc39fe66d8bf3202f162c8c6b3073919 448 SMART SM00962 100 295 6.9E-96 T 30-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CL1_0576 dc39fe66d8bf3202f162c8c6b3073919 448 SMART SM00963 2 87 2.0E-23 T 30-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CL1_0576 dc39fe66d8bf3202f162c8c6b3073919 448 Pfam PF02881 SRP54-type protein, helical bundle domain 6 83 2.4E-20 T 30-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CL1_0576 dc39fe66d8bf3202f162c8c6b3073919 448 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 268 281 - T 30-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CL1_0576 dc39fe66d8bf3202f162c8c6b3073919 448 Gene3D G3DSA:1.20.120.140 6 305 4.7E-122 T 30-10-2018 CL1_0576 dc39fe66d8bf3202f162c8c6b3073919 448 SMART SM00382 99 300 3.8E-6 T 30-10-2018 IPR003593 AAA+ ATPase domain CL1_0576 dc39fe66d8bf3202f162c8c6b3073919 448 Pfam PF02978 Signal peptide binding domain 327 425 1.8E-34 T 30-10-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 CL1_0576 dc39fe66d8bf3202f162c8c6b3073919 448 SUPERFAMILY SSF47446 297 429 3.79E-44 T 30-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 CL1_1611 d4249ed0c2dad3c7ee2ccd225e1b415f 134 TIGRFAM TIGR03081 metmalonyl_epim: methylmalonyl-CoA epimerase 4 130 4.1E-53 T 30-10-2018 IPR017515 Methylmalonyl-CoA epimerase KEGG: 00280+5.1.99.1|KEGG: 00630+5.1.99.1|KEGG: 00640+5.1.99.1|KEGG: 00720+5.1.99.1|MetaCyc: PWY-5741|MetaCyc: PWY-5743|MetaCyc: PWY-5789|MetaCyc: PWY-6728|MetaCyc: PWY-7384|MetaCyc: PWY-7854|Reactome: R-HSA-71032 CL1_1611 d4249ed0c2dad3c7ee2ccd225e1b415f 134 SUPERFAMILY SSF54593 1 132 4.79E-35 T 30-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CL1_1611 d4249ed0c2dad3c7ee2ccd225e1b415f 134 Gene3D G3DSA:3.10.180.10 1 132 1.7E-43 T 30-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CL1_1611 d4249ed0c2dad3c7ee2ccd225e1b415f 134 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 115 2.1E-25 T 30-10-2018 CL1_0655 f8e2b7847a7de95f8eafd61d356d0724 122 PIRSF PIRSF018867 1 119 4.3E-31 T 30-10-2018 IPR014497 Methylmalonyl-CoA decarboxylase, delta subunit CL1_0655 f8e2b7847a7de95f8eafd61d356d0724 122 TIGRFAM TIGR01195 oadG_fam: sodium pump decarboxylases, gamma subunit 4 81 8.6E-15 T 30-10-2018 IPR005899 Sodium ion-translocating decarboxylase GO:0008948|GO:0015081|GO:0016020|GO:0036376 KEGG: 00620+4.1.1.3 CL1_0655 f8e2b7847a7de95f8eafd61d356d0724 122 Pfam PF04277 Oxaloacetate decarboxylase, gamma chain 6 80 1.8E-15 T 30-10-2018 IPR005899 Sodium ion-translocating decarboxylase GO:0008948|GO:0015081|GO:0016020|GO:0036376 KEGG: 00620+4.1.1.3 CL1_1790 776bf38e142d2ac6ab2666a2e25621c8 289 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 3 263 1.4E-20 T 30-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain CL1_1790 776bf38e142d2ac6ab2666a2e25621c8 289 Pfam PF13187 4Fe-4S dicluster domain 68 114 2.9E-6 T 30-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CL1_1790 776bf38e142d2ac6ab2666a2e25621c8 289 SUPERFAMILY SSF54862 50 123 7.54E-18 T 30-10-2018 CL1_1790 776bf38e142d2ac6ab2666a2e25621c8 289 SUPERFAMILY SSF52540 3 284 9.08E-32 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_1790 776bf38e142d2ac6ab2666a2e25621c8 289 Gene3D G3DSA:3.30.70.20 62 115 1.4E-9 T 30-10-2018 CL1_1790 776bf38e142d2ac6ab2666a2e25621c8 289 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 99 110 - T 30-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CL1_1700 fd0f5b15e08247ee01280447cded99a6 153 Pfam PF09123 Domain of unknown function (DUF1931) 11 150 2.6E-46 T 30-10-2018 IPR015207 Protein of unknown function DUF1931 CL1_1700 fd0f5b15e08247ee01280447cded99a6 153 SUPERFAMILY SSF47113 2 153 4.54E-52 T 30-10-2018 IPR009072 Histone-fold GO:0046982 CL1_1700 fd0f5b15e08247ee01280447cded99a6 153 Gene3D G3DSA:1.10.20.10 5 153 9.0E-37 T 30-10-2018 IPR009072 Histone-fold GO:0046982 CL1_0601 56396c65170374708b82c5f239bf155f 90 Hamap MF_00349 50S ribosomal protein L34e [rpl34e]. 1 86 29.128 T 30-10-2018 IPR008195 Ribosomal protein L34Ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0601 56396c65170374708b82c5f239bf155f 90 ProSitePatterns PS01145 Ribosomal protein L34e signature. 7 20 - T 30-10-2018 IPR018065 Ribosomal protein L34e, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0601 56396c65170374708b82c5f239bf155f 90 Gene3D G3DSA:3.40.1800.40 29 86 2.0E-9 T 30-10-2018 IPR038562 Ribosomal protein L34Ae superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0601 56396c65170374708b82c5f239bf155f 90 PRINTS PR01250 Ribosomal protein L34 signature 18 35 2.6E-16 T 30-10-2018 IPR008195 Ribosomal protein L34Ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0601 56396c65170374708b82c5f239bf155f 90 PRINTS PR01250 Ribosomal protein L34 signature 56 78 2.6E-16 T 30-10-2018 IPR008195 Ribosomal protein L34Ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0601 56396c65170374708b82c5f239bf155f 90 PRINTS PR01250 Ribosomal protein L34 signature 36 46 2.6E-16 T 30-10-2018 IPR008195 Ribosomal protein L34Ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0601 56396c65170374708b82c5f239bf155f 90 PRINTS PR01250 Ribosomal protein L34 signature 5 18 2.6E-16 T 30-10-2018 IPR008195 Ribosomal protein L34Ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0601 56396c65170374708b82c5f239bf155f 90 Pfam PF01199 Ribosomal protein L34e 3 83 5.7E-24 T 30-10-2018 IPR008195 Ribosomal protein L34Ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_1256 2aa5df30c85c8b8dc1fa7751e37cdb94 343 Gene3D G3DSA:1.25.40.10 216 340 3.5E-10 T 30-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 CL1_1256 2aa5df30c85c8b8dc1fa7751e37cdb94 343 Pfam PF13174 Tetratricopeptide repeat 224 247 0.058 T 30-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CL1_1256 2aa5df30c85c8b8dc1fa7751e37cdb94 343 Pfam PF13174 Tetratricopeptide repeat 159 182 0.025 T 30-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CL1_1256 2aa5df30c85c8b8dc1fa7751e37cdb94 343 Gene3D G3DSA:1.25.40.10 98 200 9.9E-6 T 30-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 CL1_1256 2aa5df30c85c8b8dc1fa7751e37cdb94 343 SUPERFAMILY SSF103473 10 106 2.22E-5 T 30-10-2018 IPR036259 MFS transporter superfamily CL1_1256 2aa5df30c85c8b8dc1fa7751e37cdb94 343 SUPERFAMILY SSF48452 130 323 5.69E-22 T 30-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 CL1_1004 c0b2dcd04e09a4836a2ffc478dd1bad2 102 Pfam PF13601 Winged helix DNA-binding domain 17 94 1.1E-20 T 30-10-2018 IPR027395 Winged helix DNA-binding domain CL1_1004 c0b2dcd04e09a4836a2ffc478dd1bad2 102 SUPERFAMILY SSF46785 9 96 5.68E-20 T 30-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CL1_1004 c0b2dcd04e09a4836a2ffc478dd1bad2 102 SMART SM00418 6 93 0.0024 T 30-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CL1_1004 c0b2dcd04e09a4836a2ffc478dd1bad2 102 Gene3D G3DSA:1.10.10.10 1 99 1.2E-27 T 30-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CL1_0113 d8c1005c0ecd982fac01d258aafbfac7 93 SUPERFAMILY SSF56784 22 57 1.9E-5 T 30-10-2018 IPR036412 HAD-like superfamily CL1_0251 c24a63631a2ad4800a46debd0f799656 250 Hamap MF_01408 Flavin-dependent thymidylate synthase [thyX]. 5 219 30.435 T 30-10-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 CL1_0251 c24a63631a2ad4800a46debd0f799656 250 Gene3D G3DSA:3.30.1360.170 2 202 1.4E-62 T 30-10-2018 CL1_0251 c24a63631a2ad4800a46debd0f799656 250 TIGRFAM TIGR02170 thyX: thymidylate synthase, flavin-dependent 6 198 1.3E-52 T 30-10-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 CL1_0251 c24a63631a2ad4800a46debd0f799656 250 SUPERFAMILY SSF69796 5 198 1.96E-59 T 30-10-2018 IPR036098 Thymidylate synthase ThyX superfamily GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 CL1_0251 c24a63631a2ad4800a46debd0f799656 250 Pfam PF02511 Thymidylate synthase complementing protein 8 198 1.7E-62 T 30-10-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 CL1_0265 f3a9744cdc87aa035e737cba6dda9bf8 164 SMART SM00116 105 152 0.02 T 30-10-2018 IPR000644 CBS domain CL1_0265 f3a9744cdc87aa035e737cba6dda9bf8 164 SMART SM00116 24 72 1.3 T 30-10-2018 IPR000644 CBS domain CL1_0265 f3a9744cdc87aa035e737cba6dda9bf8 164 Gene3D G3DSA:3.10.580.10 80 156 2.6E-9 T 30-10-2018 CL1_0265 f3a9744cdc87aa035e737cba6dda9bf8 164 Gene3D G3DSA:3.10.580.10 1 73 1.0E-5 T 30-10-2018 CL1_0265 f3a9744cdc87aa035e737cba6dda9bf8 164 SUPERFAMILY SSF54631 5 152 6.37E-19 T 30-10-2018 CL1_0265 f3a9744cdc87aa035e737cba6dda9bf8 164 Pfam PF00571 CBS domain 24 72 5.7E-4 T 30-10-2018 IPR000644 CBS domain CL1_0265 f3a9744cdc87aa035e737cba6dda9bf8 164 Pfam PF00571 CBS domain 99 152 4.0E-6 T 30-10-2018 IPR000644 CBS domain CL1_1104 e037a6698d5bcb018ac9699228ef6208 305 SMART SM00344 155 247 0.0053 T 30-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CL1_1104 e037a6698d5bcb018ac9699228ef6208 305 Pfam PF13412 Winged helix-turn-helix DNA-binding 152 195 9.9E-10 T 30-10-2018 CL1_1104 e037a6698d5bcb018ac9699228ef6208 305 SUPERFAMILY SSF46785 155 205 2.16E-7 T 30-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CL1_1104 e037a6698d5bcb018ac9699228ef6208 305 Gene3D G3DSA:1.10.10.10 150 198 2.1E-10 T 30-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CL1_1736 558a7bcb4af1266f42bfa30b437fb129 631 Pfam PF12838 4Fe-4S dicluster domain 576 618 2.6E-9 T 30-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CL1_1736 558a7bcb4af1266f42bfa30b437fb129 631 Gene3D G3DSA:3.40.50.620 214 465 4.1E-47 T 30-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CL1_1736 558a7bcb4af1266f42bfa30b437fb129 631 SMART SM00359 133 207 1.9E-18 T 30-10-2018 IPR002478 PUA domain GO:0003723 CL1_1736 558a7bcb4af1266f42bfa30b437fb129 631 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 576 587 - T 30-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CL1_1736 558a7bcb4af1266f42bfa30b437fb129 631 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 607 618 - T 30-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CL1_1736 558a7bcb4af1266f42bfa30b437fb129 631 SUPERFAMILY SSF54862 568 623 5.71E-15 T 30-10-2018 CL1_1736 558a7bcb4af1266f42bfa30b437fb129 631 TIGRFAM TIGR00451 unchar_dom_2: uncharacterized domain 2 95 203 2.3E-11 T 30-10-2018 IPR004521 Uncharacterised domain CHP00451 GO:0003723 CL1_1736 558a7bcb4af1266f42bfa30b437fb129 631 Gene3D G3DSA:2.30.130.10 130 207 2.7E-15 T 30-10-2018 IPR036974 PUA domain superfamily GO:0003723 CL1_1736 558a7bcb4af1266f42bfa30b437fb129 631 SUPERFAMILY SSF88697 132 204 1.27E-16 T 30-10-2018 IPR015947 PUA-like superfamily CL1_1736 558a7bcb4af1266f42bfa30b437fb129 631 Pfam PF01472 PUA domain 134 204 3.9E-16 T 30-10-2018 IPR002478 PUA domain GO:0003723 CL1_1736 558a7bcb4af1266f42bfa30b437fb129 631 Gene3D G3DSA:3.30.70.20 570 622 1.1E-10 T 30-10-2018 CL1_1736 558a7bcb4af1266f42bfa30b437fb129 631 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 252 430 1.8E-42 T 30-10-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824 Reactome: R-HSA-196843 CL1_1736 558a7bcb4af1266f42bfa30b437fb129 631 SUPERFAMILY SSF52402 223 416 1.83E-43 T 30-10-2018 CL1_0937 01834e492edfb9fc35ab538c4228fd08 230 Gene3D G3DSA:3.30.70.1450 141 223 2.0E-15 T 30-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 CL1_0937 01834e492edfb9fc35ab538c4228fd08 230 SUPERFAMILY SSF51735 1 144 9.09E-37 T 30-10-2018 IPR036291 NAD(P)-binding domain superfamily CL1_0937 01834e492edfb9fc35ab538c4228fd08 230 Pfam PF02080 TrkA-C domain 153 221 1.3E-11 T 30-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CL1_0937 01834e492edfb9fc35ab538c4228fd08 230 Pfam PF02254 TrkA-N domain 3 124 1.9E-28 T 30-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 CL1_0937 01834e492edfb9fc35ab538c4228fd08 230 PRINTS PR00335 TrkA potassium uptake protein signature 2 16 2.8E-13 T 30-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 CL1_0937 01834e492edfb9fc35ab538c4228fd08 230 PRINTS PR00335 TrkA potassium uptake protein signature 49 59 2.8E-13 T 30-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 CL1_0937 01834e492edfb9fc35ab538c4228fd08 230 PRINTS PR00335 TrkA potassium uptake protein signature 60 70 2.8E-13 T 30-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 CL1_0937 01834e492edfb9fc35ab538c4228fd08 230 PRINTS PR00335 TrkA potassium uptake protein signature 73 87 2.8E-13 T 30-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 CL1_0937 01834e492edfb9fc35ab538c4228fd08 230 PRINTS PR00335 TrkA potassium uptake protein signature 19 33 2.8E-13 T 30-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 CL1_0937 01834e492edfb9fc35ab538c4228fd08 230 Gene3D G3DSA:3.40.50.720 1 140 9.7E-41 T 30-10-2018 CL1_0937 01834e492edfb9fc35ab538c4228fd08 230 SUPERFAMILY SSF116726 135 221 1.19E-12 T 30-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 CL1_1022 d752dd0adb53920bbfdd263aec464060 354 Gene3D G3DSA:1.20.81.30 173 286 4.2E-12 T 30-10-2018 CL1_1022 d752dd0adb53920bbfdd263aec464060 354 Pfam PF00482 Type II secretion system (T2SS), protein F 185 310 5.8E-24 T 30-10-2018 IPR018076 Type II secretion system F domain CL1_1107 6f512cf1eba61eb617fc5475c4b01cfc 150 SUPERFAMILY SSF46785 4 91 3.46E-12 T 30-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CL1_1107 6f512cf1eba61eb617fc5475c4b01cfc 150 Pfam PF01037 Lrp/AsnC ligand binding domain 80 142 2.0E-14 T 30-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CL1_1107 6f512cf1eba61eb617fc5475c4b01cfc 150 Pfam PF13412 Winged helix-turn-helix DNA-binding 5 52 5.1E-16 T 30-10-2018 CL1_1107 6f512cf1eba61eb617fc5475c4b01cfc 150 SUPERFAMILY SSF54909 65 147 2.15E-16 T 30-10-2018 IPR011008 Dimeric alpha-beta barrel CL1_1107 6f512cf1eba61eb617fc5475c4b01cfc 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 5 21 1.9E-13 T 30-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 CL1_1107 6f512cf1eba61eb617fc5475c4b01cfc 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 21 32 1.9E-13 T 30-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 CL1_1107 6f512cf1eba61eb617fc5475c4b01cfc 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 32 51 1.9E-13 T 30-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 CL1_1107 6f512cf1eba61eb617fc5475c4b01cfc 150 SMART SM00344 5 114 6.4E-44 T 30-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CL1_1107 6f512cf1eba61eb617fc5475c4b01cfc 150 Gene3D G3DSA:3.30.70.920 59 150 1.0E-22 T 30-10-2018 CL1_1107 6f512cf1eba61eb617fc5475c4b01cfc 150 Gene3D G3DSA:1.10.10.10 2 56 4.4E-20 T 30-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CL1_1029 821dddf836d4323804208a2ea4de6cd0 343 SUPERFAMILY SSF161098 109 303 1.31E-8 T 30-10-2018 IPR035906 MetI-like superfamily CL1_1029 821dddf836d4323804208a2ea4de6cd0 343 Gene3D G3DSA:1.10.3720.10 107 336 2.2E-12 T 30-10-2018 IPR035906 MetI-like superfamily CL1_1029 821dddf836d4323804208a2ea4de6cd0 343 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 128 342 1.9E-19 T 30-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 CL1_1978 61a6edd680c15e570d41a13777095092 960 SUPERFAMILY SSF51294 96 577 2.94E-29 T 30-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CL1_1978 61a6edd680c15e570d41a13777095092 960 Pfam PF01139 tRNA-splicing ligase RtcB 45 960 1.3E-179 T 30-10-2018 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 CL1_1978 61a6edd680c15e570d41a13777095092 960 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 556 578 8.8E-8 T 30-10-2018 IPR030934 Intein C-terminal splicing region CL1_1978 61a6edd680c15e570d41a13777095092 960 Gene3D G3DSA:3.90.1860.10 1 101 3.4E-40 T 30-10-2018 IPR036025 tRNA-splicing ligase RtcB-like superfamily GO:0006396|GO:0008452 Reactome: R-HSA-6784531 CL1_1978 61a6edd680c15e570d41a13777095092 960 Gene3D G3DSA:3.90.1860.10 559 960 3.0E-178 T 30-10-2018 IPR036025 tRNA-splicing ligase RtcB-like superfamily GO:0006396|GO:0008452 Reactome: R-HSA-6784531 CL1_1978 61a6edd680c15e570d41a13777095092 960 TIGRFAM TIGR01445 intein_Nterm: intein N-terminal splicing region 97 176 4.9E-12 T 30-10-2018 IPR006141 Intein N-terminal splicing region GO:0016539 Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CL1_1978 61a6edd680c15e570d41a13777095092 960 SMART SM00306 95 196 1.2E-22 T 30-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CL1_1978 61a6edd680c15e570d41a13777095092 960 SUPERFAMILY SSF103365 2 97 3.4E-30 T 30-10-2018 IPR036025 tRNA-splicing ligase RtcB-like superfamily GO:0006396|GO:0008452 Reactome: R-HSA-6784531 CL1_1978 61a6edd680c15e570d41a13777095092 960 SUPERFAMILY SSF103365 577 960 5.89E-147 T 30-10-2018 IPR036025 tRNA-splicing ligase RtcB-like superfamily GO:0006396|GO:0008452 Reactome: R-HSA-6784531 CL1_1978 61a6edd680c15e570d41a13777095092 960 Gene3D G3DSA:3.10.28.10 242 439 8.1E-21 T 30-10-2018 IPR027434 Homing endonuclease CL1_1978 61a6edd680c15e570d41a13777095092 960 SMART SM00305 535 583 1.6E-11 T 30-10-2018 IPR003586 Hint domain C-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CL1_1978 61a6edd680c15e570d41a13777095092 960 PRINTS PR00379 Intein signature 358 370 5.4E-12 T 30-10-2018 IPR006142 Intein GO:0016539 CL1_1978 61a6edd680c15e570d41a13777095092 960 PRINTS PR00379 Intein signature 244 256 5.4E-12 T 30-10-2018 IPR006142 Intein GO:0016539 CL1_1978 61a6edd680c15e570d41a13777095092 960 PRINTS PR00379 Intein signature 398 413 5.4E-12 T 30-10-2018 IPR006142 Intein GO:0016539 CL1_1978 61a6edd680c15e570d41a13777095092 960 PRINTS PR00379 Intein signature 572 581 5.4E-12 T 30-10-2018 IPR006142 Intein GO:0016539 CL1_1978 61a6edd680c15e570d41a13777095092 960 PRINTS PR00379 Intein signature 163 176 5.4E-12 T 30-10-2018 IPR006142 Intein GO:0016539 CL1_1978 61a6edd680c15e570d41a13777095092 960 SUPERFAMILY SSF55608 344 453 6.23E-16 T 30-10-2018 IPR027434 Homing endonuclease CL1_1978 61a6edd680c15e570d41a13777095092 960 Pfam PF14890 Intein splicing domain 113 577 2.1E-13 T 30-10-2018 CL1_1978 61a6edd680c15e570d41a13777095092 960 Pfam PF14528 LAGLIDADG-like domain 357 443 2.3E-15 T 30-10-2018 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 CL1_1978 61a6edd680c15e570d41a13777095092 960 Gene3D G3DSA:2.170.16.10 102 210 1.7E-9 T 30-10-2018 CL1_1929 3d243f3471eefd0194642daf8ba59a58 732 SMART SM00838 621 708 2.9E-46 T 30-10-2018 IPR000640 Elongation factor EFG, domain V-like CL1_1929 3d243f3471eefd0194642daf8ba59a58 732 SUPERFAMILY SSF52540 10 261 2.57E-69 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_1929 3d243f3471eefd0194642daf8ba59a58 732 Gene3D G3DSA:3.30.230.10 472 720 3.3E-75 T 30-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CL1_1929 3d243f3471eefd0194642daf8ba59a58 732 Pfam PF00679 Elongation factor G C-terminus 621 707 2.1E-24 T 30-10-2018 IPR000640 Elongation factor EFG, domain V-like CL1_1929 3d243f3471eefd0194642daf8ba59a58 732 SUPERFAMILY SSF54211 463 623 4.8E-48 T 30-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CL1_1929 3d243f3471eefd0194642daf8ba59a58 732 Gene3D G3DSA:3.30.70.870 388 465 3.6E-27 T 30-10-2018 CL1_1929 3d243f3471eefd0194642daf8ba59a58 732 Gene3D G3DSA:2.40.30.10 259 386 7.2E-28 T 30-10-2018 CL1_1929 3d243f3471eefd0194642daf8ba59a58 732 Hamap MF_00054_A Elongation factor G [fusA]. 2 725 43.79 T 30-10-2018 IPR004543 Translation elongation factor EFG/EF2, archaeal GO:0003746|GO:0005525|GO:0005737|GO:0006414 CL1_1929 3d243f3471eefd0194642daf8ba59a58 732 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 60 75 - T 30-10-2018 IPR031157 Tr-type G domain, conserved site CL1_1929 3d243f3471eefd0194642daf8ba59a58 732 SUPERFAMILY SSF50447 259 376 2.36E-33 T 30-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily CL1_1929 3d243f3471eefd0194642daf8ba59a58 732 SUPERFAMILY SSF54980 624 718 2.88E-24 T 30-10-2018 IPR035647 EF-G domain III/V-like CL1_1929 3d243f3471eefd0194642daf8ba59a58 732 Gene3D G3DSA:3.40.50.300 7 222 8.8E-74 T 30-10-2018 CL1_1929 3d243f3471eefd0194642daf8ba59a58 732 Pfam PF03764 Elongation factor G, domain IV 513 619 4.7E-27 T 30-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 CL1_1929 3d243f3471eefd0194642daf8ba59a58 732 PRINTS PR00315 GTP-binding elongation factor signature 143 152 6.6E-16 T 30-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CL1_1929 3d243f3471eefd0194642daf8ba59a58 732 PRINTS PR00315 GTP-binding elongation factor signature 67 75 6.6E-16 T 30-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CL1_1929 3d243f3471eefd0194642daf8ba59a58 732 PRINTS PR00315 GTP-binding elongation factor signature 107 118 6.6E-16 T 30-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CL1_1929 3d243f3471eefd0194642daf8ba59a58 732 PRINTS PR00315 GTP-binding elongation factor signature 23 36 6.6E-16 T 30-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CL1_1929 3d243f3471eefd0194642daf8ba59a58 732 PRINTS PR00315 GTP-binding elongation factor signature 91 101 6.6E-16 T 30-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CL1_1929 3d243f3471eefd0194642daf8ba59a58 732 TIGRFAM TIGR00490 aEF-2: translation elongation factor aEF-2 3 720 0.0 T 30-10-2018 IPR004543 Translation elongation factor EFG/EF2, archaeal GO:0003746|GO:0005525|GO:0005737|GO:0006414 CL1_1929 3d243f3471eefd0194642daf8ba59a58 732 Gene3D G3DSA:3.30.70.240 466 718 3.3E-75 T 30-10-2018 CL1_1929 3d243f3471eefd0194642daf8ba59a58 732 SUPERFAMILY SSF54980 388 463 3.2E-22 T 30-10-2018 IPR035647 EF-G domain III/V-like CL1_1929 3d243f3471eefd0194642daf8ba59a58 732 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 21 154 2.6E-20 T 30-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CL1_1929 3d243f3471eefd0194642daf8ba59a58 732 SMART SM00889 505 619 2.8E-20 T 30-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 CL1_1929 3d243f3471eefd0194642daf8ba59a58 732 Pfam PF14492 Elongation Factor G, domain II 387 459 3.8E-26 T 30-10-2018 CL1_1929 3d243f3471eefd0194642daf8ba59a58 732 Pfam PF03144 Elongation factor Tu domain 2 306 372 1.3E-14 T 30-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CL1_1929 3d243f3471eefd0194642daf8ba59a58 732 Pfam PF00009 Elongation factor Tu GTP binding domain 20 257 1.7E-64 T 30-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CL1_0903 ac7bbde571ec6bfe7f8a4b5b20fa125b 405 SUPERFAMILY SSF140914 2 249 6.8E-21 T 30-10-2018 CL1_0903 ac7bbde571ec6bfe7f8a4b5b20fa125b 405 Gene3D G3DSA:1.20.930.50 15 224 1.9E-44 T 30-10-2018 CL1_0903 ac7bbde571ec6bfe7f8a4b5b20fa125b 405 Pfam PF04104 Eukaryotic and archaeal DNA primase, large subunit 143 361 8.4E-29 T 30-10-2018 IPR007238 DNA primase large subunit, eukaryotic/archaeal GO:0003896|GO:0006269 Reactome: R-HSA-113501|Reactome: R-HSA-174411|Reactome: R-HSA-174430|Reactome: R-HSA-68952|Reactome: R-HSA-68962|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183 CL1_0903 ac7bbde571ec6bfe7f8a4b5b20fa125b 405 Gene3D G3DSA:2.20.20.80 109 171 1.9E-44 T 30-10-2018 CL1_0903 ac7bbde571ec6bfe7f8a4b5b20fa125b 405 Hamap MF_00701 DNA primase large subunit PriL [priL]. 1 389 27.365 T 30-10-2018 IPR023642 DNA primase large subunit PriL GO:0003896 CL1_1647 2f69570857333ba2c4c7816b8d121912 256 Gene3D G3DSA:3.40.190.80 144 254 3.4E-26 T 30-10-2018 CL1_1647 2f69570857333ba2c4c7816b8d121912 256 SUPERFAMILY SSF56655 6 248 4.58E-56 T 30-10-2018 CL1_1647 2f69570857333ba2c4c7816b8d121912 256 PRINTS PR00377 Inositol monophosphatase superfamily signature 40 60 5.6E-26 T 30-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CL1_1647 2f69570857333ba2c4c7816b8d121912 256 PRINTS PR00377 Inositol monophosphatase superfamily signature 129 152 5.6E-26 T 30-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CL1_1647 2f69570857333ba2c4c7816b8d121912 256 PRINTS PR00377 Inositol monophosphatase superfamily signature 197 221 5.6E-26 T 30-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CL1_1647 2f69570857333ba2c4c7816b8d121912 256 PRINTS PR00377 Inositol monophosphatase superfamily signature 164 185 5.6E-26 T 30-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CL1_1647 2f69570857333ba2c4c7816b8d121912 256 PRINTS PR00377 Inositol monophosphatase superfamily signature 80 96 5.6E-26 T 30-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CL1_1647 2f69570857333ba2c4c7816b8d121912 256 Gene3D G3DSA:3.30.540.10 3 139 3.4E-37 T 30-10-2018 CL1_1647 2f69570857333ba2c4c7816b8d121912 256 Pfam PF00459 Inositol monophosphatase family 7 253 1.8E-33 T 30-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CL1_0780 c83cba5b82ab8f1a93d60d81764409a8 331 SUPERFAMILY SSF52440 1 97 8.06E-31 T 30-10-2018 IPR016185 Pre-ATP-grasp domain superfamily CL1_0780 c83cba5b82ab8f1a93d60d81764409a8 331 Pfam PF06849 Protein of unknown function (DUF1246) 3 117 1.0E-31 T 30-10-2018 IPR010672 IMP biosynthesis enzyme PurP, N-terminal GO:0000287|GO:0005524|GO:0006188|GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 CL1_0780 c83cba5b82ab8f1a93d60d81764409a8 331 Gene3D G3DSA:3.30.1490.20 114 174 3.8E-96 T 30-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 CL1_0780 c83cba5b82ab8f1a93d60d81764409a8 331 SUPERFAMILY SSF56059 101 331 3.18E-76 T 30-10-2018 CL1_0780 c83cba5b82ab8f1a93d60d81764409a8 331 Hamap MF_01163 5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase [purP]. 1 331 48.553 T 30-10-2018 IPR023656 IMP biosynthesis enzyme PurP GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 CL1_0780 c83cba5b82ab8f1a93d60d81764409a8 331 Pfam PF06973 Domain of unknown function (DUF1297) 149 331 2.1E-71 T 30-10-2018 IPR009720 IMP biosynthesis enzyme PurP, C-terminal GO:0000287|GO:0005524|GO:0006188|GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 CL1_0780 c83cba5b82ab8f1a93d60d81764409a8 331 PIRSF PIRSF004602 1 331 1.2E-128 T 30-10-2018 IPR023656 IMP biosynthesis enzyme PurP GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 CL1_0780 c83cba5b82ab8f1a93d60d81764409a8 331 Gene3D G3DSA:3.30.470.20 87 330 3.8E-96 T 30-10-2018 CL1_0780 c83cba5b82ab8f1a93d60d81764409a8 331 Gene3D G3DSA:3.40.50.20 1 85 3.5E-28 T 30-10-2018 CL1_0155 1fd6a63d136ee6f24e579437124123a7 125 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 78 93 4.3E-16 T 30-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CL1_0155 1fd6a63d136ee6f24e579437124123a7 125 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 46 61 4.3E-16 T 30-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CL1_0155 1fd6a63d136ee6f24e579437124123a7 125 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 93 108 4.3E-16 T 30-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CL1_0155 1fd6a63d136ee6f24e579437124123a7 125 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 65 76 4.3E-16 T 30-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CL1_0155 1fd6a63d136ee6f24e579437124123a7 125 Gene3D G3DSA:1.10.10.10 12 122 1.1E-24 T 30-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CL1_0155 1fd6a63d136ee6f24e579437124123a7 125 SMART SM00418 44 122 5.1E-23 T 30-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CL1_0155 1fd6a63d136ee6f24e579437124123a7 125 SUPERFAMILY SSF46785 39 117 4.15E-21 T 30-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CL1_0155 1fd6a63d136ee6f24e579437124123a7 125 Pfam PF01022 Bacterial regulatory protein, arsR family 51 96 1.6E-12 T 30-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CL1_1100 df90592721cdba84b51fee2d2965ace5 232 Pfam PF00899 ThiF family 10 231 2.1E-56 T 30-10-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CL1_1100 df90592721cdba84b51fee2d2965ace5 232 Gene3D G3DSA:3.40.50.720 2 232 3.7E-72 T 30-10-2018 CL1_1100 df90592721cdba84b51fee2d2965ace5 232 SUPERFAMILY SSF69572 2 230 3.53E-79 T 30-10-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 CL1_0741 43f758e2b0382a85e547632538822d54 262 Pfam PF07853 Protein of unknown function (DUF1648) 134 175 3.1E-13 T 30-10-2018 IPR012867 Domain of unknown function DUF1648 CL1_0741 43f758e2b0382a85e547632538822d54 262 Pfam PF13630 SdpI/YhfL protein family 28 85 1.8E-12 T 30-10-2018 IPR025962 SdpI/YhfL protein family CL1_0808 5b868a2d7acd6dd40eb3e6e11ee2bb36 195 Pfam PF02676 Methyltransferase TYW3 11 192 7.9E-46 T 30-10-2018 IPR003827 tRNA wybutosine-synthesizing protein MetaCyc: PWY-7286|Reactome: R-HSA-6782861 CL1_0808 5b868a2d7acd6dd40eb3e6e11ee2bb36 195 SUPERFAMILY SSF111278 7 192 8.76E-61 T 30-10-2018 IPR036602 tRNA wybutosine-synthesizing-like superfamily MetaCyc: PWY-7286|Reactome: R-HSA-6782861 CL1_0808 5b868a2d7acd6dd40eb3e6e11ee2bb36 195 Hamap MF_00266 tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase [taw3]. 9 195 30.764 T 30-10-2018 IPR022908 tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase GO:0008175|GO:0030488|GO:0031591 MetaCyc: PWY-7286 CL1_0808 5b868a2d7acd6dd40eb3e6e11ee2bb36 195 Gene3D G3DSA:3.30.1960.10 2 195 2.3E-67 T 30-10-2018 IPR036602 tRNA wybutosine-synthesizing-like superfamily MetaCyc: PWY-7286|Reactome: R-HSA-6782861 CL1_0759 bef5f9805a0ad4db23f574195b1dcbb5 62 Pfam PF06093 Spt4/RpoE2 zinc finger 4 62 2.8E-16 T 30-10-2018 IPR022800 Spt4/RpoE2 zinc finger Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-75955 CL1_0759 bef5f9805a0ad4db23f574195b1dcbb5 62 SUPERFAMILY SSF63393 3 62 4.18E-23 T 30-10-2018 IPR029040 RNA polymerase subunit RPABC4/transcription elongation factor Spt4 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-75955 CL1_0759 bef5f9805a0ad4db23f574195b1dcbb5 62 Gene3D G3DSA:2.20.28.90 1 62 6.9E-33 T 30-10-2018 IPR038589 Archaeal transcription elongation factor Spt4 superfamily CL1_0759 bef5f9805a0ad4db23f574195b1dcbb5 62 Hamap MF_00949 Transcription elongation factor Spt4 [spt4]. 6 62 28.826 T 30-10-2018 IPR007178 Archaeal transcription elongation factor Spt4 GO:0006355 CL1_0759 bef5f9805a0ad4db23f574195b1dcbb5 62 ProDom PD019197 RNA DNA-DIRECTED POLYMERASE SUBUNIT E'' POLYMERASE RPOE2 TRANSFERASE NUCLEOTIDYLTRANSFERASE E 19 61 3.0E-15 T 30-10-2018 IPR007178 Archaeal transcription elongation factor Spt4 GO:0006355 CL1_0759 bef5f9805a0ad4db23f574195b1dcbb5 62 SMART SM01389 4 62 2.6E-30 T 30-10-2018 IPR022800 Spt4/RpoE2 zinc finger Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-75955 CL1_0469 f007fd07471fe60d92c4789f5fd312e3 465 SUPERFAMILY SSF53448 1 271 5.01E-67 T 30-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases CL1_0469 f007fd07471fe60d92c4789f5fd312e3 465 Gene3D G3DSA:2.60.120.10 351 451 1.0E-18 T 30-10-2018 IPR014710 RmlC-like jelly roll fold CL1_0469 f007fd07471fe60d92c4789f5fd312e3 465 Pfam PF01050 Mannose-6-phosphate isomerase 310 460 1.0E-66 T 30-10-2018 IPR001538 Mannose-6-phosphate isomerase, type II, C-terminal GO:0005976|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882 CL1_0469 f007fd07471fe60d92c4789f5fd312e3 465 SUPERFAMILY SSF51182 191 464 1.65E-69 T 30-10-2018 IPR011051 RmlC-like cupin domain superfamily CL1_0469 f007fd07471fe60d92c4789f5fd312e3 465 TIGRFAM TIGR01479 GMP_PMI: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase 3 463 2.7E-156 T 30-10-2018 IPR006375 Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase GO:0000271|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882 CL1_0469 f007fd07471fe60d92c4789f5fd312e3 465 Gene3D G3DSA:3.90.550.10 1 345 4.4E-112 T 30-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases CL1_0469 f007fd07471fe60d92c4789f5fd312e3 465 Pfam PF00483 Nucleotidyl transferase 2 277 1.2E-57 T 30-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 CL1_0532 ea517bba0df7934b3d172f30e6eb71a5 202 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 4 50 1.6E-15 T 30-10-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 CL1_0532 ea517bba0df7934b3d172f30e6eb71a5 202 Gene3D G3DSA:3.40.50.1390 53 154 3.3E-28 T 30-10-2018 CL1_0532 ea517bba0df7934b3d172f30e6eb71a5 202 SUPERFAMILY SSF53041 56 188 1.83E-26 T 30-10-2018 IPR036162 Resolvase-like, N-terminal catalytic domain superfamily GO:0000150|GO:0003677|GO:0006310 CL1_0532 ea517bba0df7934b3d172f30e6eb71a5 202 Gene3D G3DSA:1.10.1660.10 2 52 4.3E-7 T 30-10-2018 CL1_0532 ea517bba0df7934b3d172f30e6eb71a5 202 SMART SM00857 57 180 2.5E-27 T 30-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CL1_0532 ea517bba0df7934b3d172f30e6eb71a5 202 Pfam PF12728 Helix-turn-helix domain 3 52 2.5E-13 T 30-10-2018 CL1_0532 ea517bba0df7934b3d172f30e6eb71a5 202 ProSitePatterns PS00397 Site-specific recombinases active site. 60 68 - T 30-10-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 CL1_0532 ea517bba0df7934b3d172f30e6eb71a5 202 SUPERFAMILY SSF46955 2 50 5.31E-6 T 30-10-2018 IPR009061 Putative DNA-binding domain superfamily CL1_0532 ea517bba0df7934b3d172f30e6eb71a5 202 Pfam PF00239 Resolvase, N terminal domain 57 189 1.4E-25 T 30-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CL1_0747 a612be05f74c6412ae6dc018616cd7a1 562 Gene3D G3DSA:3.50.30.30 73 208 7.0E-55 T 30-10-2018 CL1_0747 a612be05f74c6412ae6dc018616cd7a1 562 Gene3D G3DSA:3.40.630.10 28 405 7.0E-55 T 30-10-2018 CL1_0747 a612be05f74c6412ae6dc018616cd7a1 562 SUPERFAMILY SSF53187 10 420 7.54E-32 T 30-10-2018 CL1_0747 a612be05f74c6412ae6dc018616cd7a1 562 Pfam PF04389 Peptidase family M28 228 412 8.7E-19 T 30-10-2018 IPR007484 Peptidase M28 CL1_0046 af2b371921acab13adb523839350663f 616 SUPERFAMILY SSF50993 2 352 2.56E-39 T 30-10-2018 CL1_0046 af2b371921acab13adb523839350663f 616 Pfam PF00326 Prolyl oligopeptidase family 412 614 1.6E-54 T 30-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 CL1_0046 af2b371921acab13adb523839350663f 616 Pfam PF02897 Prolyl oligopeptidase, N-terminal beta-propeller domain 2 352 2.0E-15 T 30-10-2018 IPR023302 Peptidase S9A, N-terminal domain GO:0004252|GO:0070008 CL1_0046 af2b371921acab13adb523839350663f 616 Gene3D G3DSA:3.40.50.1820 2 610 7.0E-133 T 30-10-2018 IPR029058 Alpha/Beta hydrolase fold CL1_0046 af2b371921acab13adb523839350663f 616 Gene3D G3DSA:2.130.10.120 49 362 7.0E-133 T 30-10-2018 CL1_0046 af2b371921acab13adb523839350663f 616 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 475 495 4.3E-53 T 30-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 CL1_0046 af2b371921acab13adb523839350663f 616 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 548 570 4.3E-53 T 30-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 CL1_0046 af2b371921acab13adb523839350663f 616 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 449 468 4.3E-53 T 30-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 CL1_0046 af2b371921acab13adb523839350663f 616 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 421 445 4.3E-53 T 30-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 CL1_0046 af2b371921acab13adb523839350663f 616 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 395 413 4.3E-53 T 30-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 CL1_0046 af2b371921acab13adb523839350663f 616 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 530 545 4.3E-53 T 30-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 CL1_0046 af2b371921acab13adb523839350663f 616 SUPERFAMILY SSF53474 368 614 1.64E-50 T 30-10-2018 IPR029058 Alpha/Beta hydrolase fold CL1_1637 12b1b11f452598e6bf207565a9cef0ba 121 Pfam PF05168 HEPN domain 3 115 1.7E-23 T 30-10-2018 IPR007842 HEPN domain CL1_1637 12b1b11f452598e6bf207565a9cef0ba 121 Gene3D G3DSA:1.20.120.330 1 120 2.5E-30 T 30-10-2018 CL1_1637 12b1b11f452598e6bf207565a9cef0ba 121 SUPERFAMILY SSF81593 4 117 2.94E-8 T 30-10-2018 CL1_1117 e3220a7eaa6c0994654a4e75c1ce084e 430 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 7 426 1.2E-199 T 30-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CL1_1117 e3220a7eaa6c0994654a4e75c1ce084e 430 Pfam PF00113 Enolase, C-terminal TIM barrel domain 141 427 4.8E-131 T 30-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CL1_1117 e3220a7eaa6c0994654a4e75c1ce084e 430 ProSitePatterns PS00164 Enolase signature. 337 350 - T 30-10-2018 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CL1_1117 e3220a7eaa6c0994654a4e75c1ce084e 430 Hamap MF_00318 Enolase [eno]. 5 414 46.141 T 30-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CL1_1117 e3220a7eaa6c0994654a4e75c1ce084e 430 SMART SM01193 7 135 4.6E-96 T 30-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CL1_1117 e3220a7eaa6c0994654a4e75c1ce084e 430 SUPERFAMILY SSF54826 6 140 3.98E-58 T 30-10-2018 CL1_1117 e3220a7eaa6c0994654a4e75c1ce084e 430 SUPERFAMILY SSF51604 139 428 5.11E-126 T 30-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily CL1_1117 e3220a7eaa6c0994654a4e75c1ce084e 430 Pfam PF03952 Enolase, N-terminal domain 7 135 3.8E-60 T 30-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CL1_1117 e3220a7eaa6c0994654a4e75c1ce084e 430 PRINTS PR00148 Enolase signature 108 124 1.0E-50 T 30-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CL1_1117 e3220a7eaa6c0994654a4e75c1ce084e 430 PRINTS PR00148 Enolase signature 162 175 1.0E-50 T 30-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CL1_1117 e3220a7eaa6c0994654a4e75c1ce084e 430 PRINTS PR00148 Enolase signature 337 351 1.0E-50 T 30-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CL1_1117 e3220a7eaa6c0994654a4e75c1ce084e 430 PRINTS PR00148 Enolase signature 39 53 1.0E-50 T 30-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CL1_1117 e3220a7eaa6c0994654a4e75c1ce084e 430 PRINTS PR00148 Enolase signature 314 325 1.0E-50 T 30-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CL1_1117 e3220a7eaa6c0994654a4e75c1ce084e 430 PRINTS PR00148 Enolase signature 366 383 1.0E-50 T 30-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CL1_1117 e3220a7eaa6c0994654a4e75c1ce084e 430 Gene3D G3DSA:3.20.20.120 129 428 7.8E-135 T 30-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily CL1_1117 e3220a7eaa6c0994654a4e75c1ce084e 430 SMART SM01192 140 428 2.1E-209 T 30-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CL1_1117 e3220a7eaa6c0994654a4e75c1ce084e 430 PIRSF PIRSF001400 3 427 7.8E-197 T 30-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CL1_1117 e3220a7eaa6c0994654a4e75c1ce084e 430 Gene3D G3DSA:3.30.390.10 2 128 1.2E-56 T 30-10-2018 IPR029017 Enolase-like, N-terminal CL1_1398 1c15ac9fece625813860f550fca125f4 322 TIGRFAM TIGR00524 eIF-2B_rel: eIF-2B alpha/beta/delta-related uncharacterized proteins 5 299 2.3E-97 T 30-10-2018 IPR011559 Initiation factor 2B alpha/beta/delta GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 CL1_1398 1c15ac9fece625813860f550fca125f4 322 TIGRFAM TIGR00511 ribulose_e2b2: ribose-1,5-bisphosphate isomerase, e2b2 family 6 312 1.5E-147 T 30-10-2018 IPR005250 Ribose-1,5-bisphosphate isomerase, e2b2 family MetaCyc: PWY-5532 CL1_1398 1c15ac9fece625813860f550fca125f4 322 Gene3D G3DSA:3.40.50.10470 115 310 1.4E-84 T 30-10-2018 CL1_1398 1c15ac9fece625813860f550fca125f4 322 Gene3D G3DSA:1.20.120.420 1 114 6.7E-47 T 30-10-2018 IPR027363 Methylthioribose-1-phosphate isomerase, N-terminal KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 CL1_1398 1c15ac9fece625813860f550fca125f4 322 Pfam PF01008 Initiation factor 2 subunit family 19 299 6.2E-93 T 30-10-2018 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 CL1_1398 1c15ac9fece625813860f550fca125f4 322 SUPERFAMILY SSF100950 4 311 1.26E-101 T 30-10-2018 IPR037171 NagB/RpiA transferase-like CL1_0057 c81c4b9af379cf147b1727cc8d41b1cc 257 SUPERFAMILY SSF56281 17 241 1.29E-32 T 30-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like CL1_0057 c81c4b9af379cf147b1727cc8d41b1cc 257 Gene3D G3DSA:3.60.15.10 6 242 3.5E-43 T 30-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like CL1_0057 c81c4b9af379cf147b1727cc8d41b1cc 257 SMART SM00849 33 224 3.8E-18 T 30-10-2018 IPR001279 Metallo-beta-lactamase CL1_0057 c81c4b9af379cf147b1727cc8d41b1cc 257 Pfam PF00753 Metallo-beta-lactamase superfamily 34 224 5.9E-15 T 30-10-2018 IPR001279 Metallo-beta-lactamase CL1_1023 d122fdd8f9e2ee24c2aaa1b270d493a3 622 Pfam PF00437 Type II/IV secretion system protein 228 484 2.7E-64 T 30-10-2018 IPR001482 Type II/IV secretion system protein CL1_1023 d122fdd8f9e2ee24c2aaa1b270d493a3 622 SUPERFAMILY SSF52540 208 589 2.44E-57 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_1023 d122fdd8f9e2ee24c2aaa1b270d493a3 622 Gene3D G3DSA:3.30.450.380 105 322 1.9E-65 T 30-10-2018 CL1_1023 d122fdd8f9e2ee24c2aaa1b270d493a3 622 SMART SM00382 355 520 0.0017 T 30-10-2018 IPR003593 AAA+ ATPase domain CL1_1023 d122fdd8f9e2ee24c2aaa1b270d493a3 622 Gene3D G3DSA:3.40.50.300 323 610 1.2E-101 T 30-10-2018 CL1_0053 181899de952225e11ed936fcf24e50bd 362 Gene3D G3DSA:1.10.8.60 206 283 1.1E-23 T 30-10-2018 CL1_0053 181899de952225e11ed936fcf24e50bd 362 SUPERFAMILY SSF46785 286 360 1.71E-14 T 30-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CL1_0053 181899de952225e11ed936fcf24e50bd 362 Gene3D G3DSA:1.10.10.10 288 362 1.1E-19 T 30-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CL1_0053 181899de952225e11ed936fcf24e50bd 362 SUPERFAMILY SSF52540 2 277 1.09E-43 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_0053 181899de952225e11ed936fcf24e50bd 362 Pfam PF01637 ATPase domain predominantly from Archaea 15 247 4.1E-16 T 30-10-2018 IPR011579 ATPase domain GO:0005524 CL1_0053 181899de952225e11ed936fcf24e50bd 362 Gene3D G3DSA:3.40.50.300 1 204 5.4E-43 T 30-10-2018 CL1_0356 9b4a3b507c54a6d1a50a76bb537e2036 118 TIGRFAM TIGR00283 arch_pth2: peptidyl-tRNA hydrolase 5 117 3.3E-43 T 30-10-2018 IPR002833 Peptidyl-tRNA hydrolase, PTH2 GO:0004045 MetaCyc: PWY-6308 CL1_0356 9b4a3b507c54a6d1a50a76bb537e2036 118 Pfam PF01981 Peptidyl-tRNA hydrolase PTH2 4 117 1.6E-43 T 30-10-2018 IPR002833 Peptidyl-tRNA hydrolase, PTH2 GO:0004045 MetaCyc: PWY-6308 CL1_0356 9b4a3b507c54a6d1a50a76bb537e2036 118 Hamap MF_00628 Peptidyl-tRNA hydrolase [pth]. 4 118 30.093 T 30-10-2018 IPR034759 Peptidyl-tRNA hydrolase, archaea GO:0004045 MetaCyc: PWY-6308 CL1_0356 9b4a3b507c54a6d1a50a76bb537e2036 118 Gene3D G3DSA:3.40.1490.10 1 118 5.5E-48 T 30-10-2018 IPR023476 Peptidyl-tRNA hydrolase II domain superfamily MetaCyc: PWY-6308 CL1_0356 9b4a3b507c54a6d1a50a76bb537e2036 118 SUPERFAMILY SSF102462 3 117 2.62E-42 T 30-10-2018 IPR023476 Peptidyl-tRNA hydrolase II domain superfamily MetaCyc: PWY-6308 CL1_0298 32ef2e2cbf036e6bf9f5db3fab74b2b2 177 Gene3D G3DSA:2.40.320.10 1 177 5.4E-56 T 30-10-2018 CL1_0298 32ef2e2cbf036e6bf9f5db3fab74b2b2 177 TIGRFAM TIGR00318 cyaB: putative adenylyl cyclase CyaB 2 173 1.9E-45 T 30-10-2018 IPR008173 Adenylyl cyclase CyaB KEGG: 00230+4.6.1.1 CL1_0298 32ef2e2cbf036e6bf9f5db3fab74b2b2 177 Pfam PF01928 CYTH domain 2 169 4.5E-33 T 30-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 CL1_0298 32ef2e2cbf036e6bf9f5db3fab74b2b2 177 SMART SM01118 1 175 9.9E-24 T 30-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 CL1_0298 32ef2e2cbf036e6bf9f5db3fab74b2b2 177 SUPERFAMILY SSF55154 2 173 7.36E-37 T 30-10-2018 IPR033469 CYTH-like domain superfamily Reactome: R-HSA-196819 CL1_0298 32ef2e2cbf036e6bf9f5db3fab74b2b2 177 ProDom PD009560 CYCLASE ADENYLATE CYCLASE ADENYLYL CYAB LYASE CLASS CYAB-TYPE THERMOPHILIC MJ0240 1 152 6.0E-66 T 30-10-2018 CL1_1242 2e5cc544bffd0c09d4c22116c24336ff 231 SUPERFAMILY SSF143555 14 180 3.27E-48 T 30-10-2018 CL1_1242 2e5cc544bffd0c09d4c22116c24336ff 231 Gene3D G3DSA:3.30.1330.130 4 173 1.3E-42 T 30-10-2018 CL1_1242 2e5cc544bffd0c09d4c22116c24336ff 231 PIRSF PIRSF006578 4 216 1.4E-49 T 30-10-2018 IPR026328 Formylmethanofuran dehydrogenase, subunit E CL1_1242 2e5cc544bffd0c09d4c22116c24336ff 231 Pfam PF02663 FmdE, Molybdenum formylmethanofuran dehydrogenase operon 23 165 2.4E-37 T 30-10-2018 IPR003814 Formylmethanofuran dehydrogenase, subunit E domain CL1_1242 2e5cc544bffd0c09d4c22116c24336ff 231 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 181 215 1.7E-7 T 30-10-2018 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 CL1_0927 edbd692d30e4fbc4d5b576d9cb9a4ecf 408 Gene3D G3DSA:3.30.980.10 92 247 5.8E-42 T 30-10-2018 CL1_0927 edbd692d30e4fbc4d5b576d9cb9a4ecf 408 Pfam PF01411 tRNA synthetases class II (A) 25 94 5.0E-11 T 30-10-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 CL1_0927 edbd692d30e4fbc4d5b576d9cb9a4ecf 408 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 191 234 1.8E-11 T 30-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 CL1_0927 edbd692d30e4fbc4d5b576d9cb9a4ecf 408 SUPERFAMILY SSF55186 92 238 7.33E-36 T 30-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 CL1_0927 edbd692d30e4fbc4d5b576d9cb9a4ecf 408 Gene3D G3DSA:2.40.30.130 1 90 1.0E-19 T 30-10-2018 CL1_0927 edbd692d30e4fbc4d5b576d9cb9a4ecf 408 SUPERFAMILY SSF50447 1 89 8.12E-15 T 30-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily CL1_0927 edbd692d30e4fbc4d5b576d9cb9a4ecf 408 SMART SM00863 191 234 9.7E-15 T 30-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 CL1_0927 edbd692d30e4fbc4d5b576d9cb9a4ecf 408 Gene3D G3DSA:3.10.310.40 302 403 6.2E-9 T 30-10-2018 CL1_0927 edbd692d30e4fbc4d5b576d9cb9a4ecf 408 Pfam PF02272 DHHA1 domain 270 401 1.7E-12 T 30-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 CL1_0720 1c20c93a04acee498ffad4b46af3ef6c 154 SMART SM00419 21 72 5.1E-10 T 30-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CL1_0720 1c20c93a04acee498ffad4b46af3ef6c 154 Pfam PF12802 MarR family 7 65 4.7E-8 T 30-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CL1_0720 1c20c93a04acee498ffad4b46af3ef6c 154 Pfam PF01037 Lrp/AsnC ligand binding domain 87 152 1.3E-8 T 30-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CL1_0720 1c20c93a04acee498ffad4b46af3ef6c 154 Gene3D G3DSA:1.10.10.10 7 78 1.8E-8 T 30-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CL1_0720 1c20c93a04acee498ffad4b46af3ef6c 154 SUPERFAMILY SSF46785 31 138 1.9E-10 T 30-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CL1_0720 1c20c93a04acee498ffad4b46af3ef6c 154 Gene3D G3DSA:3.30.70.920 79 154 1.7E-10 T 30-10-2018 CL1_0281 c3cda511e1a816d25a0fe93d8249da73 137 SUPERFAMILY SSF160975 2 130 1.28E-68 T 30-10-2018 CL1_0281 c3cda511e1a816d25a0fe93d8249da73 137 Pfam PF04919 Protein of unknown function (DUF655) 3 129 2.6E-54 T 30-10-2018 IPR007003 Protein of unknown function DUF655 CL1_0281 c3cda511e1a816d25a0fe93d8249da73 137 Gene3D G3DSA:1.10.150.280 24 121 3.6E-43 T 30-10-2018 CL1_1749 49463ea4a109c83bb77f144323d763aa 334 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 110 290 1.6E-67 T 30-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CL1_1749 49463ea4a109c83bb77f144323d763aa 334 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 5 322 2.5E-38 T 30-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 CL1_1749 49463ea4a109c83bb77f144323d763aa 334 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 230 246 - T 30-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CL1_1749 49463ea4a109c83bb77f144323d763aa 334 Hamap MF_00776 Glyoxylate reductase [gyaR]. 1 331 59.804 T 30-10-2018 IPR023519 Glyoxylate reductase GyaR GO:0047964|GO:0055114 KEGG: 00630+1.1.1.26|MetaCyc: PWY-7294|MetaCyc: PWY-7295 CL1_1749 49463ea4a109c83bb77f144323d763aa 334 Gene3D G3DSA:3.40.50.720 98 290 2.4E-142 T 30-10-2018 CL1_1749 49463ea4a109c83bb77f144323d763aa 334 SUPERFAMILY SSF51735 103 290 1.32E-65 T 30-10-2018 IPR036291 NAD(P)-binding domain superfamily CL1_1749 49463ea4a109c83bb77f144323d763aa 334 SUPERFAMILY SSF52283 3 133 6.99E-43 T 30-10-2018 CL1_1749 49463ea4a109c83bb77f144323d763aa 334 Gene3D G3DSA:3.40.50.720 4 317 2.4E-142 T 30-10-2018 CL1_0596 81dbed83faab8f08b4462174672e2f43 149 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 8 148 25.32 T 30-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0596 81dbed83faab8f08b4462174672e2f43 149 TIGRFAM TIGR03629 uS13_arch: ribosomal protein uS13 4 148 1.8E-61 T 30-10-2018 IPR019977 Ribosomal protein S13, archaeal GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CL1_0596 81dbed83faab8f08b4462174672e2f43 149 PIRSF PIRSF002134 2 149 2.2E-41 T 30-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0596 81dbed83faab8f08b4462174672e2f43 149 Gene3D G3DSA:4.10.910.10 88 138 4.3E-20 T 30-10-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0596 81dbed83faab8f08b4462174672e2f43 149 ProSitePatterns PS00646 Ribosomal protein S13 signature. 117 130 - T 30-10-2018 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0596 81dbed83faab8f08b4462174672e2f43 149 SUPERFAMILY SSF46946 9 144 2.19E-34 T 30-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 CL1_0596 81dbed83faab8f08b4462174672e2f43 149 Gene3D G3DSA:1.10.8.50 1 76 2.4E-26 T 30-10-2018 CL1_0596 81dbed83faab8f08b4462174672e2f43 149 Pfam PF00416 Ribosomal protein S13/S18 10 137 3.9E-41 T 30-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0339 69f0c007f292bf4297b35b05b5fa96e0 568 SUPERFAMILY SSF56037 142 261 2.22E-6 T 30-10-2018 CL1_0339 69f0c007f292bf4297b35b05b5fa96e0 568 Gene3D G3DSA:3.30.56.10 1 80 9.0E-23 T 30-10-2018 CL1_0339 69f0c007f292bf4297b35b05b5fa96e0 568 Gene3D G3DSA:3.30.56.10 279 348 2.6E-25 T 30-10-2018 CL1_0339 69f0c007f292bf4297b35b05b5fa96e0 568 Gene3D G3DSA:3.50.40.10 81 278 2.5E-74 T 30-10-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 KEGG: 00970+6.1.1.20 CL1_0339 69f0c007f292bf4297b35b05b5fa96e0 568 Hamap MF_00284 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 560 35.842 T 30-10-2018 IPR022918 Phenylalanine-tRNA ligase beta chain 2, bacterial/archaeal GO:0004826 KEGG: 00970+6.1.1.20 CL1_0339 69f0c007f292bf4297b35b05b5fa96e0 568 SMART SM00873 100 259 1.9E-21 T 30-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 CL1_0339 69f0c007f292bf4297b35b05b5fa96e0 568 SUPERFAMILY SSF46955 281 352 7.05E-15 T 30-10-2018 IPR009061 Putative DNA-binding domain superfamily CL1_0339 69f0c007f292bf4297b35b05b5fa96e0 568 Pfam PF03483 B3/4 domain 119 243 1.4E-16 T 30-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 CL1_0339 69f0c007f292bf4297b35b05b5fa96e0 568 Gene3D G3DSA:3.30.930.10 367 562 3.8E-52 T 30-10-2018 CL1_0339 69f0c007f292bf4297b35b05b5fa96e0 568 SUPERFAMILY SSF55681 345 562 3.23E-43 T 30-10-2018 CL1_0339 69f0c007f292bf4297b35b05b5fa96e0 568 Pfam PF03484 tRNA synthetase B5 domain 284 348 2.9E-12 T 30-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 CL1_0339 69f0c007f292bf4297b35b05b5fa96e0 568 TIGRFAM TIGR00471 pheT_arch: phenylalanine--tRNA ligase, beta subunit 1 557 6.6E-175 T 30-10-2018 IPR004531 Phenylalanyl-tRNA synthetase, class IIc, beta subunit, archae/euk cytosolic GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 CL1_0339 69f0c007f292bf4297b35b05b5fa96e0 568 SUPERFAMILY SSF46955 5 81 3.2E-9 T 30-10-2018 IPR009061 Putative DNA-binding domain superfamily CL1_0339 69f0c007f292bf4297b35b05b5fa96e0 568 SMART SM00874 280 348 5.6E-17 T 30-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 CL1_0645 cbf7b4af782187f7a102475c662e36e9 101 SUPERFAMILY SSF50447 20 99 6.83E-9 T 30-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily CL1_0645 cbf7b4af782187f7a102475c662e36e9 101 Gene3D G3DSA:2.40.30.10 13 101 5.8E-16 T 30-10-2018 CL1_1724 70eaefb5a1bbf096b82e42f6370efb6a 444 SMART SM00220 69 331 3.3E-49 T 30-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CL1_1724 70eaefb5a1bbf096b82e42f6370efb6a 444 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 188 200 - T 30-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 CL1_1724 70eaefb5a1bbf096b82e42f6370efb6a 444 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 75 98 - T 30-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 CL1_1724 70eaefb5a1bbf096b82e42f6370efb6a 444 Gene3D G3DSA:1.10.510.10 62 400 6.3E-65 T 30-10-2018 CL1_1724 70eaefb5a1bbf096b82e42f6370efb6a 444 Pfam PF00069 Protein kinase domain 69 319 2.2E-46 T 30-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CL1_1724 70eaefb5a1bbf096b82e42f6370efb6a 444 SUPERFAMILY SSF56112 61 327 1.03E-65 T 30-10-2018 IPR011009 Protein kinase-like domain superfamily CL1_1027 689b8e649183ad718502cad683c0fec4 357 Gene3D G3DSA:1.10.1580.10 169 252 1.8E-13 T 30-10-2018 IPR023179 GTP-binding protein, orthogonal bundle domain superfamily CL1_1027 689b8e649183ad718502cad683c0fec4 357 SUPERFAMILY SSF52540 4 168 1.94E-38 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_1027 689b8e649183ad718502cad683c0fec4 357 Pfam PF01926 50S ribosome-binding GTPase 107 162 7.1E-13 T 30-10-2018 IPR006073 GTP binding domain GO:0005525 CL1_1027 689b8e649183ad718502cad683c0fec4 357 Gene3D G3DSA:3.40.50.300 5 162 5.1E-45 T 30-10-2018 CL1_0440 fda6dc561252b5d74e9862345ad592df 1122 Pfam PF04563 RNA polymerase beta subunit 28 381 9.9E-55 T 30-10-2018 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CL1_0440 fda6dc561252b5d74e9862345ad592df 1122 Gene3D G3DSA:3.90.1100.10 337 511 1.1E-55 T 30-10-2018 CL1_0440 fda6dc561252b5d74e9862345ad592df 1122 Pfam PF04561 RNA polymerase Rpb2, domain 2 175 348 6.5E-41 T 30-10-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CL1_0440 fda6dc561252b5d74e9862345ad592df 1122 Pfam PF04567 RNA polymerase Rpb2, domain 5 605 637 8.1E-9 T 30-10-2018 IPR007647 RNA polymerase Rpb2, domain 5 GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CL1_0440 fda6dc561252b5d74e9862345ad592df 1122 Pfam PF00562 RNA polymerase Rpb2, domain 6 653 1025 4.0E-132 T 30-10-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CL1_0440 fda6dc561252b5d74e9862345ad592df 1122 Pfam PF04566 RNA polymerase Rpb2, domain 4 521 584 4.5E-19 T 30-10-2018 IPR007646 RNA polymerase Rpb2, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CL1_0440 fda6dc561252b5d74e9862345ad592df 1122 ProSitePatterns PS01166 RNA polymerases beta chain signature. 878 890 - T 30-10-2018 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CL1_0440 fda6dc561252b5d74e9862345ad592df 1122 Gene3D G3DSA:2.40.270.10 653 1011 3.7E-147 T 30-10-2018 IPR037033 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CL1_0440 fda6dc561252b5d74e9862345ad592df 1122 Gene3D G3DSA:3.90.1100.10 21 177 2.5E-12 T 30-10-2018 CL1_0440 fda6dc561252b5d74e9862345ad592df 1122 Gene3D G3DSA:3.90.1110.10 178 336 2.3E-59 T 30-10-2018 IPR037034 RNA polymerase Rpb2, domain 2 superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CL1_0440 fda6dc561252b5d74e9862345ad592df 1122 SUPERFAMILY SSF64484 12 1118 0.0 T 30-10-2018 CL1_0440 fda6dc561252b5d74e9862345ad592df 1122 Gene3D G3DSA:2.40.50.150 683 874 3.7E-147 T 30-10-2018 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CL1_0440 fda6dc561252b5d74e9862345ad592df 1122 TIGRFAM TIGR03670 rpoB_arch: DNA-directed RNA polymerase subunit B 521 1121 0.0 T 30-10-2018 IPR019969 DNA-directed RNA polymerase subunit B (Rpo2) GO:0003677|GO:0003899|GO:0006351|GO:0008270 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CL1_0440 fda6dc561252b5d74e9862345ad592df 1122 Pfam PF04565 RNA polymerase Rpb2, domain 3 424 488 1.7E-30 T 30-10-2018 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CL1_0440 fda6dc561252b5d74e9862345ad592df 1122 Gene3D G3DSA:3.90.1800.10 1012 1120 5.8E-41 T 30-10-2018 CL1_0440 fda6dc561252b5d74e9862345ad592df 1122 Pfam PF04560 RNA polymerase Rpb2, domain 7 1027 1116 7.1E-31 T 30-10-2018 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CL1_1253 8c8c6af4be7a071bc5a0238c122bab84 111 TIGRFAM TIGR00264 TIGR00264: alpha-NAC homolog 3 109 4.0E-36 T 30-10-2018 IPR005231 Nascent polypeptide-associated complex (NAC), archaeal GO:0003723 CL1_1253 8c8c6af4be7a071bc5a0238c122bab84 111 SMART SM01407 6 66 2.7E-18 T 30-10-2018 IPR002715 Nascent polypeptide-associated complex NAC domain CL1_1253 8c8c6af4be7a071bc5a0238c122bab84 111 Pfam PF01849 NAC domain 6 64 8.1E-12 T 30-10-2018 IPR002715 Nascent polypeptide-associated complex NAC domain CL1_1253 8c8c6af4be7a071bc5a0238c122bab84 111 SUPERFAMILY SSF46934 70 108 8.68E-8 T 30-10-2018 IPR009060 UBA-like superfamily GO:0005515 CL1_1253 8c8c6af4be7a071bc5a0238c122bab84 111 Gene3D G3DSA:2.20.70.30 10 68 3.7E-23 T 30-10-2018 IPR038187 NAC A/B domain superfamily CL1_1253 8c8c6af4be7a071bc5a0238c122bab84 111 Hamap MF_00814 Nascent polypeptide-associated complex protein [nac]. 7 109 21.263 T 30-10-2018 IPR005231 Nascent polypeptide-associated complex (NAC), archaeal GO:0003723 CL1_1253 8c8c6af4be7a071bc5a0238c122bab84 111 Gene3D G3DSA:1.10.8.10 70 109 1.6E-19 T 30-10-2018 CL1_0240 6c7135e8a1c92698a60102b3ca4d7dde 275 Gene3D G3DSA:3.20.20.100 10 273 3.1E-88 T 30-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily CL1_0240 6c7135e8a1c92698a60102b3ca4d7dde 275 Pfam PF00248 Aldo/keto reductase family 18 270 1.9E-61 T 30-10-2018 IPR023210 NADP-dependent oxidoreductase domain CL1_0240 6c7135e8a1c92698a60102b3ca4d7dde 275 PIRSF PIRSF000097 5 123 4.8E-18 T 30-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CL1_0240 6c7135e8a1c92698a60102b3ca4d7dde 275 PIRSF PIRSF000097 122 273 6.3E-19 T 30-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CL1_0240 6c7135e8a1c92698a60102b3ca4d7dde 275 PRINTS PR00069 Aldo-keto reductase signature 209 233 1.2E-19 T 30-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CL1_0240 6c7135e8a1c92698a60102b3ca4d7dde 275 PRINTS PR00069 Aldo-keto reductase signature 134 151 1.2E-19 T 30-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CL1_0240 6c7135e8a1c92698a60102b3ca4d7dde 275 PRINTS PR00069 Aldo-keto reductase signature 46 70 1.2E-19 T 30-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CL1_0240 6c7135e8a1c92698a60102b3ca4d7dde 275 PRINTS PR00069 Aldo-keto reductase signature 102 120 1.2E-19 T 30-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CL1_0240 6c7135e8a1c92698a60102b3ca4d7dde 275 SUPERFAMILY SSF51430 13 269 3.8E-76 T 30-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily CL1_0240 6c7135e8a1c92698a60102b3ca4d7dde 275 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 134 151 - T 30-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CL1_1049 ddbdab0b8adfc305db559d203730314e 242 Pfam PF09754 PAC2 family 19 222 1.4E-44 T 30-10-2018 IPR019151 Proteasome assembly chaperone 2 CL1_1049 ddbdab0b8adfc305db559d203730314e 242 SUPERFAMILY SSF159659 11 230 1.19E-46 T 30-10-2018 CL1_1049 ddbdab0b8adfc305db559d203730314e 242 TIGRFAM TIGR00161 TIGR00161: TIGR00161 family protein 12 235 1.2E-63 T 30-10-2018 IPR004425 Conserved hypothetical protein CHP00061 CL1_1049 ddbdab0b8adfc305db559d203730314e 242 Gene3D G3DSA:3.40.50.10900 1 242 7.0E-71 T 30-10-2018 IPR038389 Proteasome assembly chaperone 2 superfamily CL1_1010 609deab8a5d8b0c0c9b47cf6261c8269 122 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 3 119 10.076 T 30-10-2018 IPR022907 VapC family GO:0004540 CL1_1010 609deab8a5d8b0c0c9b47cf6261c8269 122 Pfam PF01850 PIN domain 4 113 2.2E-11 T 30-10-2018 IPR002716 PIN domain CL1_1010 609deab8a5d8b0c0c9b47cf6261c8269 122 Gene3D G3DSA:3.40.50.1010 2 122 4.7E-26 T 30-10-2018 CL1_1010 609deab8a5d8b0c0c9b47cf6261c8269 122 SUPERFAMILY SSF88723 2 119 9.25E-28 T 30-10-2018 IPR029060 PIN-like domain superfamily CL1_1585 1c5b75921a53212dc65226b1b336734f 341 SMART SM00484 140 221 4.3E-38 T 30-10-2018 IPR006086 XPG-I domain GO:0004518 CL1_1585 1c5b75921a53212dc65226b1b336734f 341 Pfam PF00752 XPG N-terminal domain 12 100 6.6E-22 T 30-10-2018 IPR006085 XPG N-terminal GO:0004518|GO:0006281 CL1_1585 1c5b75921a53212dc65226b1b336734f 341 SMART SM00485 1 101 3.8E-50 T 30-10-2018 IPR006085 XPG N-terminal GO:0004518|GO:0006281 CL1_1585 1c5b75921a53212dc65226b1b336734f 341 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 139 156 5.9E-33 T 30-10-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 CL1_1585 1c5b75921a53212dc65226b1b336734f 341 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 21 35 5.9E-33 T 30-10-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 CL1_1585 1c5b75921a53212dc65226b1b336734f 341 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 226 241 5.9E-33 T 30-10-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 CL1_1585 1c5b75921a53212dc65226b1b336734f 341 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 75 94 5.9E-33 T 30-10-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 CL1_1585 1c5b75921a53212dc65226b1b336734f 341 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 160 180 5.9E-33 T 30-10-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 CL1_1585 1c5b75921a53212dc65226b1b336734f 341 Gene3D G3DSA:3.40.50.1010 1 220 7.5E-88 T 30-10-2018 CL1_1585 1c5b75921a53212dc65226b1b336734f 341 Gene3D G3DSA:1.10.150.20 221 281 2.2E-20 T 30-10-2018 CL1_1585 1c5b75921a53212dc65226b1b336734f 341 SUPERFAMILY SSF47807 221 339 1.64E-33 T 30-10-2018 IPR036279 5'-3' exonuclease, C-terminal domain superfamily CL1_1585 1c5b75921a53212dc65226b1b336734f 341 TIGRFAM TIGR03674 fen_arch: flap structure-specific endonuclease 1 338 4.9E-156 T 30-10-2018 IPR019973 Flap structure-specific endonuclease, archaea GO:0016788 CL1_1585 1c5b75921a53212dc65226b1b336734f 341 Hamap MF_00614 Flap endonuclease 1 [fen]. 1 340 147.125 T 30-10-2018 IPR023426 Flap endonuclease 1 GO:0016788 Reactome: R-HSA-110362|Reactome: R-HSA-162594|Reactome: R-HSA-174437|Reactome: R-HSA-5651801|Reactome: R-HSA-5685939|Reactome: R-HSA-69166 CL1_1585 1c5b75921a53212dc65226b1b336734f 341 SMART SM00279 223 257 1.0E-11 T 30-10-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 CL1_1585 1c5b75921a53212dc65226b1b336734f 341 Pfam PF00867 XPG I-region 141 236 8.8E-29 T 30-10-2018 IPR006086 XPG-I domain GO:0004518 CL1_1585 1c5b75921a53212dc65226b1b336734f 341 SUPERFAMILY SSF88723 8 236 1.34E-66 T 30-10-2018 IPR029060 PIN-like domain superfamily CL1_1585 1c5b75921a53212dc65226b1b336734f 341 ProSitePatterns PS00841 XPG protein signature 1. 73 87 - T 30-10-2018 IPR019974 XPG conserved site GO:0016788 CL1_1616 2adaffbeaa8d853c8eb9c7cdc7f7a7d5 785 SUPERFAMILY SSF47781 713 782 7.04E-16 T 30-10-2018 IPR010994 RuvA domain 2-like CL1_1616 2adaffbeaa8d853c8eb9c7cdc7f7a7d5 785 Gene3D G3DSA:3.40.50.10130 571 712 2.6E-53 T 30-10-2018 CL1_1616 2adaffbeaa8d853c8eb9c7cdc7f7a7d5 785 SUPERFAMILY SSF52540 52 480 8.91E-59 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_1616 2adaffbeaa8d853c8eb9c7cdc7f7a7d5 785 Pfam PF02732 ERCC4 domain 578 696 7.9E-29 T 30-10-2018 IPR006166 ERCC4 domain GO:0003677|GO:0004518 Reactome: R-HSA-6783310 CL1_1616 2adaffbeaa8d853c8eb9c7cdc7f7a7d5 785 SMART SM00891 575 655 1.9E-31 T 30-10-2018 IPR006166 ERCC4 domain GO:0003677|GO:0004518 Reactome: R-HSA-6783310 CL1_1616 2adaffbeaa8d853c8eb9c7cdc7f7a7d5 785 Gene3D G3DSA:1.10.150.20 713 785 4.2E-23 T 30-10-2018 CL1_1616 2adaffbeaa8d853c8eb9c7cdc7f7a7d5 785 Gene3D G3DSA:1.20.1320.20 212 338 3.7E-99 T 30-10-2018 CL1_1616 2adaffbeaa8d853c8eb9c7cdc7f7a7d5 785 SUPERFAMILY SSF52980 573 701 2.04E-37 T 30-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CL1_1616 2adaffbeaa8d853c8eb9c7cdc7f7a7d5 785 Pfam PF00271 Helicase conserved C-terminal domain 343 460 5.6E-23 T 30-10-2018 IPR001650 Helicase, C-terminal CL1_1616 2adaffbeaa8d853c8eb9c7cdc7f7a7d5 785 Pfam PF00270 DEAD/DEAH box helicase 14 168 2.6E-18 T 30-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CL1_1616 2adaffbeaa8d853c8eb9c7cdc7f7a7d5 785 Pfam PF12826 Helix-hairpin-helix motif 730 781 6.1E-10 T 30-10-2018 CL1_1616 2adaffbeaa8d853c8eb9c7cdc7f7a7d5 785 SMART SM00487 6 201 6.2E-31 T 30-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CL1_1616 2adaffbeaa8d853c8eb9c7cdc7f7a7d5 785 SMART SM00278 758 777 0.038 T 30-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CL1_1616 2adaffbeaa8d853c8eb9c7cdc7f7a7d5 785 SMART SM00278 726 745 1000.0 T 30-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CL1_1616 2adaffbeaa8d853c8eb9c7cdc7f7a7d5 785 SMART SM00490 372 461 1.7E-23 T 30-10-2018 IPR001650 Helicase, C-terminal CL1_1616 2adaffbeaa8d853c8eb9c7cdc7f7a7d5 785 Gene3D G3DSA:3.40.50.300 1 199 3.8E-73 T 30-10-2018 CL1_1616 2adaffbeaa8d853c8eb9c7cdc7f7a7d5 785 Gene3D G3DSA:3.40.50.300 209 478 3.7E-99 T 30-10-2018 CL1_0403 8f36c191a98207f551d6f6663e05e9bf 105 TIGRFAM TIGR03685 ribo_P1_arch: 50S ribosomal protein P1 1 105 3.5E-42 T 30-10-2018 IPR022295 Ribosomal protein L12, archaea GO:0003735|GO:0005840|GO:0006414 CL1_0403 8f36c191a98207f551d6f6663e05e9bf 105 Hamap MF_01478 50S ribosomal protein L12 [rpl12]. 1 102 14.258 T 30-10-2018 IPR027534 Ribosomal protein L12 family GO:0003735|GO:0005622|GO:0005840|GO:0006414 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0403 8f36c191a98207f551d6f6663e05e9bf 105 Pfam PF00428 60s Acidic ribosomal protein 16 104 1.0E-19 T 30-10-2018 CL1_0403 8f36c191a98207f551d6f6663e05e9bf 105 Gene3D G3DSA:1.10.10.1410 1 58 3.3E-31 T 30-10-2018 IPR038716 Ribosomal protein P1/P2, N-terminal domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0038 e5aa5907e88481404ea0c2502eb54c01 426 TIGRFAM TIGR00190 thiC: phosphomethylpyrimidine synthase 1 422 6.8E-185 T 30-10-2018 IPR002817 Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 CL1_0038 e5aa5907e88481404ea0c2502eb54c01 426 Hamap MF_00089 Phosphomethylpyrimidine synthase [thiC]. 1 425 86.403 T 30-10-2018 IPR037509 Phosphomethylpyrimidine synthase GO:0009228|GO:0016830 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 CL1_0038 e5aa5907e88481404ea0c2502eb54c01 426 Pfam PF01964 Radical SAM ThiC family 2 420 1.3E-179 T 30-10-2018 IPR002817 Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 CL1_0038 e5aa5907e88481404ea0c2502eb54c01 426 Gene3D G3DSA:3.20.20.540 44 362 3.4E-136 T 30-10-2018 IPR038521 ThiC/Bza superfamily KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 CL1_0064 b61af08d2330b8095fdcea60b379f319 151 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 4 144 11.182 T 30-10-2018 IPR022907 VapC family GO:0004540 CL1_0064 b61af08d2330b8095fdcea60b379f319 151 SMART SM00670 2 135 1.5E-13 T 30-10-2018 IPR002716 PIN domain CL1_0064 b61af08d2330b8095fdcea60b379f319 151 SUPERFAMILY SSF88723 1 136 1.23E-20 T 30-10-2018 IPR029060 PIN-like domain superfamily CL1_0064 b61af08d2330b8095fdcea60b379f319 151 Pfam PF01850 PIN domain 5 136 5.9E-21 T 30-10-2018 IPR002716 PIN domain CL1_0064 b61af08d2330b8095fdcea60b379f319 151 Gene3D G3DSA:3.40.50.1010 4 145 1.2E-13 T 30-10-2018 CL1_1816 bb3228661ae1768133e78f0fd973eee2 327 TIGRFAM TIGR02585 cas_Cst2_DevR: CRISPR-associated protein Cas7/Cst2/DevR, subtype I-B/TNEAP 9 307 8.7E-88 T 30-10-2018 IPR013414 CRISPR-associated protein Cas7, subtype I-B/Tneap CL1_1816 bb3228661ae1768133e78f0fd973eee2 327 Pfam PF01905 CRISPR-associated negative auto-regulator DevR/Csa2 12 259 5.6E-20 T 30-10-2018 IPR010154 CRISPR-associated protein Cas7/Cst2/DevR CL1_1816 bb3228661ae1768133e78f0fd973eee2 327 TIGRFAM TIGR01875 cas_MJ0381: CRISPR-associated autoregulator DevR family 5 247 7.5E-60 T 30-10-2018 IPR010154 CRISPR-associated protein Cas7/Cst2/DevR CL1_0485 33b403f8947fbb268a51d2b446f22b7c 74 Pfam PF01455 HupF/HypC family 1 65 2.0E-30 T 30-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC CL1_0485 33b403f8947fbb268a51d2b446f22b7c 74 TIGRFAM TIGR00074 hypC_hupF: hydrogenase assembly chaperone HypC/HupF 1 72 3.9E-28 T 30-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC CL1_0485 33b403f8947fbb268a51d2b446f22b7c 74 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 2 9 8.8E-15 T 30-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC CL1_0485 33b403f8947fbb268a51d2b446f22b7c 74 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 56 68 8.8E-15 T 30-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC CL1_0485 33b403f8947fbb268a51d2b446f22b7c 74 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 17 33 8.8E-15 T 30-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC CL1_0485 33b403f8947fbb268a51d2b446f22b7c 74 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 38 54 8.8E-15 T 30-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC CL1_0485 33b403f8947fbb268a51d2b446f22b7c 74 SUPERFAMILY SSF159127 1 73 2.22E-27 T 30-10-2018 IPR037254 HupF/HypC superfamily CL1_0485 33b403f8947fbb268a51d2b446f22b7c 74 Gene3D G3DSA:2.40.50.970 1 74 1.7E-33 T 30-10-2018 IPR037254 HupF/HypC superfamily CL1_0485 33b403f8947fbb268a51d2b446f22b7c 74 ProSitePatterns PS01097 Hydrogenases expression/synthesis hupF/hypC family signature. 1 9 - T 30-10-2018 IPR019812 Hydrogenase assembly chaperone, conserved site CL1_0457 22334dcaa335269a4a30e9edb51c5895 94 ProSitePatterns PS01172 Ribosomal protein L44e signature. 60 71 - T 30-10-2018 IPR000552 Ribosomal protein L44e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0457 22334dcaa335269a4a30e9edb51c5895 94 Pfam PF00935 Ribosomal protein L44 16 92 4.7E-26 T 30-10-2018 IPR000552 Ribosomal protein L44e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0457 22334dcaa335269a4a30e9edb51c5895 94 SUPERFAMILY SSF57829 1 93 2.93E-30 T 30-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 CL1_0457 22334dcaa335269a4a30e9edb51c5895 94 ProDom PD002841 RIBOSOMAL RIBONUCLEOPROTEIN 60S L44 L44E L41 RESISTANCE 50S ANTIBIOTIC CYCLOHEXIMIDE 9 93 4.0E-40 T 30-10-2018 IPR000552 Ribosomal protein L44e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0457 22334dcaa335269a4a30e9edb51c5895 94 Gene3D G3DSA:3.10.450.80 1 93 3.4E-31 T 30-10-2018 CL1_0457 22334dcaa335269a4a30e9edb51c5895 94 Hamap MF_01476 50S ribosomal protein L44e [rpl44e]. 1 92 24.954 T 30-10-2018 IPR000552 Ribosomal protein L44e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_1508 5614c6a07fbb0433cb934e052b9d2cd7 184 Pfam PF13023 HD domain 11 151 1.8E-32 T 30-10-2018 IPR006674 HD domain CL1_1508 5614c6a07fbb0433cb934e052b9d2cd7 184 Gene3D G3DSA:1.10.3210.10 2 182 4.4E-62 T 30-10-2018 CL1_1508 5614c6a07fbb0433cb934e052b9d2cd7 184 SUPERFAMILY SSF109604 3 175 1.22E-43 T 30-10-2018 CL1_1508 5614c6a07fbb0433cb934e052b9d2cd7 184 SMART SM00471 28 146 4.7E-14 T 30-10-2018 IPR003607 HD/PDEase domain CL1_1235 f0628cbc06609b5914b3e9c084f7286b 179 TIGRFAM TIGR00373 TIGR00373: transcription factor E 10 165 1.9E-48 T 30-10-2018 IPR016481 Transcription factor TFE, archaea GO:0006355 CL1_1235 f0628cbc06609b5914b3e9c084f7286b 179 Gene3D G3DSA:1.10.10.10 4 87 2.5E-27 T 30-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CL1_1235 f0628cbc06609b5914b3e9c084f7286b 179 SUPERFAMILY SSF46785 6 87 5.22E-24 T 30-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CL1_1235 f0628cbc06609b5914b3e9c084f7286b 179 PIRSF PIRSF006373 1 177 5.4E-71 T 30-10-2018 IPR016481 Transcription factor TFE, archaea GO:0006355 CL1_1235 f0628cbc06609b5914b3e9c084f7286b 179 Hamap MF_01909 Transcription factor E [tfe]. 3 166 26.673 T 30-10-2018 IPR016481 Transcription factor TFE, archaea GO:0006355 CL1_1235 f0628cbc06609b5914b3e9c084f7286b 179 SMART SM00531 19 158 2.0E-54 T 30-10-2018 IPR002853 Transcription initiation factor IIE subunit alpha, N-terminal GO:0006367 Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-674695|Reactome: R-HSA-6807505|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-76042 CL1_1235 f0628cbc06609b5914b3e9c084f7286b 179 Pfam PF02002 TFIIE alpha subunit 11 110 4.9E-24 T 30-10-2018 IPR024550 TFIIEalpha/SarR/Rpc3 HTH domain Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-674695|Reactome: R-HSA-6807505|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-76042 CL1_0781 4decc4fe8bb194706dbe34adc5eb9e70 713 SUPERFAMILY SSF56042 184 402 4.04E-51 T 30-10-2018 IPR036676 PurM-like, C-terminal domain superfamily CL1_0781 4decc4fe8bb194706dbe34adc5eb9e70 713 SUPERFAMILY SSF55326 376 534 3.4E-48 T 30-10-2018 IPR036921 PurM-like, N-terminal domain superfamily CL1_0781 4decc4fe8bb194706dbe34adc5eb9e70 713 SUPERFAMILY SSF55326 19 178 4.58E-47 T 30-10-2018 IPR036921 PurM-like, N-terminal domain superfamily CL1_0781 4decc4fe8bb194706dbe34adc5eb9e70 713 SUPERFAMILY SSF56042 544 704 6.43E-36 T 30-10-2018 IPR036676 PurM-like, C-terminal domain superfamily CL1_0781 4decc4fe8bb194706dbe34adc5eb9e70 713 Pfam PF00586 AIR synthase related protein, N-terminal domain 59 172 1.3E-24 T 30-10-2018 IPR016188 PurM-like, N-terminal domain CL1_0781 4decc4fe8bb194706dbe34adc5eb9e70 713 Pfam PF00586 AIR synthase related protein, N-terminal domain 417 533 1.3E-18 T 30-10-2018 IPR016188 PurM-like, N-terminal domain CL1_0781 4decc4fe8bb194706dbe34adc5eb9e70 713 Gene3D G3DSA:3.30.1330.10 27 175 1.4E-118 T 30-10-2018 IPR036921 PurM-like, N-terminal domain superfamily CL1_0781 4decc4fe8bb194706dbe34adc5eb9e70 713 Hamap MF_00420 Phosphoribosylformylglycinamidine synthase subunit PurL [purL]. 1 713 251.787 T 30-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CL1_0781 4decc4fe8bb194706dbe34adc5eb9e70 713 Gene3D G3DSA:3.90.650.10 12 340 1.4E-118 T 30-10-2018 IPR036676 PurM-like, C-terminal domain superfamily CL1_0781 4decc4fe8bb194706dbe34adc5eb9e70 713 Pfam PF02769 AIR synthase related protein, C-terminal domain 575 680 2.1E-18 T 30-10-2018 IPR010918 PurM-like, C-terminal domain CL1_0781 4decc4fe8bb194706dbe34adc5eb9e70 713 Pfam PF02769 AIR synthase related protein, C-terminal domain 185 340 1.6E-36 T 30-10-2018 IPR010918 PurM-like, C-terminal domain CL1_0781 4decc4fe8bb194706dbe34adc5eb9e70 713 TIGRFAM TIGR01736 FGAM_synth_II: phosphoribosylformylglycinamidine synthase II 2 703 9.4E-289 T 30-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CL1_0781 4decc4fe8bb194706dbe34adc5eb9e70 713 Gene3D G3DSA:3.90.650.10 543 709 4.3E-36 T 30-10-2018 IPR036676 PurM-like, C-terminal domain superfamily CL1_0781 4decc4fe8bb194706dbe34adc5eb9e70 713 Gene3D G3DSA:3.30.1330.10 365 536 6.3E-54 T 30-10-2018 IPR036921 PurM-like, N-terminal domain superfamily CL1_0781 4decc4fe8bb194706dbe34adc5eb9e70 713 PIRSF PIRSF001587 1 712 1.2E-277 T 30-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CL1_1568 0ce916930717d85df41b415c08914ebf 795 Pfam PF02359 Cell division protein 48 (CDC48), N-terminal domain 8 91 2.7E-35 T 30-10-2018 IPR003338 CDC48, N-terminal subdomain CL1_1568 0ce916930717d85df41b415c08914ebf 795 SUPERFAMILY SSF50692 2 90 1.82E-30 T 30-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily CL1_1568 0ce916930717d85df41b415c08914ebf 795 TIGRFAM TIGR01243 CDC48: AAA family ATPase, CDC48 subfamily 7 793 0.0 T 30-10-2018 IPR005938 AAA ATPase, CDC48 family GO:0016787 Reactome: R-HSA-110320|Reactome: R-HSA-3371511|Reactome: R-HSA-382556|Reactome: R-HSA-532668|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5678895|Reactome: R-HSA-5689877|Reactome: R-HSA-5689896|Reactome: R-HSA-6798695|Reactome: R-HSA-8866654|Reactome: R-HSA-8876725 CL1_1568 0ce916930717d85df41b415c08914ebf 795 Gene3D G3DSA:1.10.8.60 684 792 3.5E-34 T 30-10-2018 CL1_1568 0ce916930717d85df41b415c08914ebf 795 SUPERFAMILY SSF52540 179 502 1.94E-70 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_1568 0ce916930717d85df41b415c08914ebf 795 SUPERFAMILY SSF54585 92 184 2.65E-20 T 30-10-2018 IPR029067 CDC48 domain 2-like superfamily CL1_1568 0ce916930717d85df41b415c08914ebf 795 Pfam PF02933 Cell division protein 48 (CDC48), domain 2 108 169 2.7E-14 T 30-10-2018 IPR004201 CDC48, domain 2 CL1_1568 0ce916930717d85df41b415c08914ebf 795 Gene3D G3DSA:3.40.50.300 508 682 9.9E-75 T 30-10-2018 CL1_1568 0ce916930717d85df41b415c08914ebf 795 SMART SM01072 107 170 8.3E-18 T 30-10-2018 IPR004201 CDC48, domain 2 CL1_1568 0ce916930717d85df41b415c08914ebf 795 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 219 348 1.8E-51 T 30-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CL1_1568 0ce916930717d85df41b415c08914ebf 795 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 553 682 1.8E-49 T 30-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CL1_1568 0ce916930717d85df41b415c08914ebf 795 SMART SM01073 8 92 9.4E-44 T 30-10-2018 IPR003338 CDC48, N-terminal subdomain CL1_1568 0ce916930717d85df41b415c08914ebf 795 ProSitePatterns PS00674 AAA-protein family signature. 319 337 - T 30-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 CL1_1568 0ce916930717d85df41b415c08914ebf 795 Gene3D G3DSA:2.40.40.20 1 91 7.6E-37 T 30-10-2018 CL1_1568 0ce916930717d85df41b415c08914ebf 795 Gene3D G3DSA:3.10.330.10 92 163 1.7E-6 T 30-10-2018 CL1_1568 0ce916930717d85df41b415c08914ebf 795 Gene3D G3DSA:3.40.50.300 164 366 7.2E-81 T 30-10-2018 CL1_1568 0ce916930717d85df41b415c08914ebf 795 SUPERFAMILY SSF52540 511 790 2.59E-80 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_1568 0ce916930717d85df41b415c08914ebf 795 Gene3D G3DSA:1.10.8.60 391 505 1.6E-17 T 30-10-2018 CL1_1568 0ce916930717d85df41b415c08914ebf 795 ProSitePatterns PS00674 AAA-protein family signature. 653 671 - T 30-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 CL1_1568 0ce916930717d85df41b415c08914ebf 795 SMART SM00382 215 351 1.7E-25 T 30-10-2018 IPR003593 AAA+ ATPase domain CL1_1568 0ce916930717d85df41b415c08914ebf 795 SMART SM00382 549 685 8.9E-25 T 30-10-2018 IPR003593 AAA+ ATPase domain CL1_0334 30e1f0041efb7c52d78f974a37520314 305 SUPERFAMILY SSF52540 2 229 9.13E-56 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_0334 30e1f0041efb7c52d78f974a37520314 305 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 30-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CL1_0334 30e1f0041efb7c52d78f974a37520314 305 Gene3D G3DSA:3.40.50.300 1 241 4.8E-59 T 30-10-2018 CL1_0334 30e1f0041efb7c52d78f974a37520314 305 SMART SM00382 26 229 2.0E-10 T 30-10-2018 IPR003593 AAA+ ATPase domain CL1_0334 30e1f0041efb7c52d78f974a37520314 305 Pfam PF00005 ABC transporter 17 167 1.4E-30 T 30-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CL1_0334 30e1f0041efb7c52d78f974a37520314 305 Pfam PF13732 Domain of unknown function (DUF4162) 222 304 1.3E-6 T 30-10-2018 IPR025302 Domain of unknown function DUF4162 CL1_1148 2c04ef964432db33a56e6f32213ab83b 712 Gene3D G3DSA:2.40.40.20 574 693 7.6E-42 T 30-10-2018 CL1_1148 2c04ef964432db33a56e6f32213ab83b 712 SUPERFAMILY SSF50692 545 691 5.88E-48 T 30-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily CL1_1148 2c04ef964432db33a56e6f32213ab83b 712 SMART SM00926 12 68 2.4E-5 T 30-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CL1_1148 2c04ef964432db33a56e6f32213ab83b 712 PIRSF PIRSF000144 547 697 0.071 T 30-10-2018 CL1_1148 2c04ef964432db33a56e6f32213ab83b 712 PIRSF PIRSF000144 60 435 1.8E-64 T 30-10-2018 CL1_1148 2c04ef964432db33a56e6f32213ab83b 712 SUPERFAMILY SSF53706 15 586 5.5E-214 T 30-10-2018 CL1_1148 2c04ef964432db33a56e6f32213ab83b 712 Gene3D G3DSA:3.40.228.10 147 345 3.1E-191 T 30-10-2018 CL1_1148 2c04ef964432db33a56e6f32213ab83b 712 Gene3D G3DSA:2.20.25.90 13 67 6.2E-8 T 30-10-2018 CL1_1148 2c04ef964432db33a56e6f32213ab83b 712 Pfam PF00384 Molybdopterin oxidoreductase 70 491 3.5E-94 T 30-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CL1_1148 2c04ef964432db33a56e6f32213ab83b 712 ProSitePatterns PS00490 Prokaryotic molybdopterin oxidoreductases signature 2. 437 454 - T 30-10-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 CL1_1148 2c04ef964432db33a56e6f32213ab83b 712 Pfam PF01568 Molydopterin dinucleotide binding domain 584 687 1.1E-30 T 30-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 CL1_1148 2c04ef964432db33a56e6f32213ab83b 712 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 16 66 5.7E-7 T 30-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CL1_1148 2c04ef964432db33a56e6f32213ab83b 712 Gene3D G3DSA:3.40.50.740 79 541 3.1E-191 T 30-10-2018 CL1_1148 2c04ef964432db33a56e6f32213ab83b 712 TIGRFAM TIGR01591 Fdh-alpha: formate dehydrogenase, alpha subunit 17 690 5.2E-245 T 30-10-2018 IPR006478 Formate dehydrogenase, alpha subunit GO:0008863|GO:0015942|GO:0055114 KEGG: 00630+1.17.1.9|KEGG: 00680+1.17.1.9|MetaCyc: PWY-1881|MetaCyc: PWY-5497|MetaCyc: PWY-6696|MetaCyc: PWY-7985 CL1_1053 84a1e9194c720404c0676d79b426473e 344 Gene3D G3DSA:1.10.287.70 5 102 1.5E-21 T 30-10-2018 CL1_1053 84a1e9194c720404c0676d79b426473e 344 Pfam PF02254 TrkA-N domain 121 241 7.2E-18 T 30-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 CL1_1053 84a1e9194c720404c0676d79b426473e 344 Pfam PF07885 Ion channel 29 101 3.4E-17 T 30-10-2018 IPR013099 Potassium channel domain CL1_1053 84a1e9194c720404c0676d79b426473e 344 PRINTS PR01333 Two pore domain K+ channel signature 121 130 1.5E-7 T 30-10-2018 IPR003280 Two pore domain potassium channel GO:0005267|GO:0016020|GO:0071805 Reactome: R-HSA-5576886 CL1_1053 84a1e9194c720404c0676d79b426473e 344 PRINTS PR01333 Two pore domain K+ channel signature 57 85 1.5E-7 T 30-10-2018 IPR003280 Two pore domain potassium channel GO:0005267|GO:0016020|GO:0071805 Reactome: R-HSA-5576886 CL1_1053 84a1e9194c720404c0676d79b426473e 344 Gene3D G3DSA:3.40.50.720 116 266 2.6E-27 T 30-10-2018 CL1_1053 84a1e9194c720404c0676d79b426473e 344 SUPERFAMILY SSF51735 116 264 6.89E-22 T 30-10-2018 IPR036291 NAD(P)-binding domain superfamily CL1_1053 84a1e9194c720404c0676d79b426473e 344 SUPERFAMILY SSF81324 19 136 2.75E-28 T 30-10-2018 CL1_0816 442deb9c2f71ce2705e026046349b5ca 545 Pfam PF00118 TCP-1/cpn60 chaperonin family 35 525 1.8E-182 T 30-10-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 CL1_0816 442deb9c2f71ce2705e026046349b5ca 545 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 89 108 1.2E-34 T 30-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 CL1_0816 442deb9c2f71ce2705e026046349b5ca 545 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 37 53 1.2E-34 T 30-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 CL1_0816 442deb9c2f71ce2705e026046349b5ca 545 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 407 419 1.2E-34 T 30-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 CL1_0816 442deb9c2f71ce2705e026046349b5ca 545 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 373 395 1.2E-34 T 30-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 CL1_0816 442deb9c2f71ce2705e026046349b5ca 545 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 59 77 1.2E-34 T 30-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 CL1_0816 442deb9c2f71ce2705e026046349b5ca 545 ProSitePatterns PS00995 Chaperonins TCP-1 signature 3. 89 97 - T 30-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 CL1_0816 442deb9c2f71ce2705e026046349b5ca 545 ProSitePatterns PS00751 Chaperonins TCP-1 signature 2. 61 77 - T 30-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 CL1_0816 442deb9c2f71ce2705e026046349b5ca 545 TIGRFAM TIGR02339 thermosome_arch: thermosome, various subunits, archaeal 8 524 3.5E-243 T 30-10-2018 IPR012714 Thermosome, archaeal GO:0005524|GO:0006457|GO:0051082 CL1_0816 442deb9c2f71ce2705e026046349b5ca 545 Gene3D G3DSA:3.30.260.10 147 405 4.6E-212 T 30-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily CL1_0816 442deb9c2f71ce2705e026046349b5ca 545 Gene3D G3DSA:1.10.560.10 28 522 4.6E-212 T 30-10-2018 IPR027413 GroEL-like equatorial domain superfamily CL1_0816 442deb9c2f71ce2705e026046349b5ca 545 SUPERFAMILY SSF52029 212 378 2.51E-63 T 30-10-2018 IPR027409 GroEL-like apical domain superfamily CL1_0816 442deb9c2f71ce2705e026046349b5ca 545 SUPERFAMILY SSF54849 147 405 8.85E-29 T 30-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily CL1_0816 442deb9c2f71ce2705e026046349b5ca 545 ProSitePatterns PS00750 Chaperonins TCP-1 signature 1. 40 52 - T 30-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 CL1_0816 442deb9c2f71ce2705e026046349b5ca 545 Gene3D G3DSA:3.50.7.10 218 369 4.6E-212 T 30-10-2018 IPR027409 GroEL-like apical domain superfamily CL1_0816 442deb9c2f71ce2705e026046349b5ca 545 SUPERFAMILY SSF48592 17 524 6.28E-92 T 30-10-2018 IPR027413 GroEL-like equatorial domain superfamily CL1_2023 bfbcc020a406e438684e37bb9a428373 294 TIGRFAM TIGR00380 cobD: cobalamin biosynthesis protein CobD 5 283 9.8E-84 T 30-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 CL1_2023 bfbcc020a406e438684e37bb9a428373 294 Hamap MF_00024 Cobalamin biosynthesis protein CbiB [cbiB]. 1 291 80.247 T 30-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 CL1_2023 bfbcc020a406e438684e37bb9a428373 294 Pfam PF03186 CobD/Cbib protein 8 268 7.5E-85 T 30-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 CL1_1832 a2a0829255a580e75051fa36fb591914 247 Pfam PF12730 ABC-2 family transporter protein 55 173 5.0E-7 T 30-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 CL1_1844 d0c96f843db52944e71fafa7d34e418d 117 PIRSF PIRSF021774 1 117 4.2E-23 T 30-10-2018 IPR016796 Uncharacterised conserved protein UCP021774 CL1_1844 d0c96f843db52944e71fafa7d34e418d 117 SUPERFAMILY SSF103247 1 104 9.16E-26 T 30-10-2018 IPR035923 TT1751-like domain superfamily CL1_1844 d0c96f843db52944e71fafa7d34e418d 117 Gene3D G3DSA:3.30.310.70 1 117 5.5E-24 T 30-10-2018 IPR035923 TT1751-like domain superfamily CL1_1844 d0c96f843db52944e71fafa7d34e418d 117 Pfam PF03625 Domain of unknown function DUF302 37 94 4.4E-17 T 30-10-2018 IPR005180 Domain of unknown function DUF302 CL1_0827 12ef09d17fb40ba366d70d9567364c76 449 SUPERFAMILY SSF48179 220 314 1.02E-27 T 30-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 CL1_0827 12ef09d17fb40ba366d70d9567364c76 449 SUPERFAMILY SSF51735 21 213 1.8E-38 T 30-10-2018 IPR036291 NAD(P)-binding domain superfamily CL1_0827 12ef09d17fb40ba366d70d9567364c76 449 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 221 308 1.0E-22 T 30-10-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CL1_0827 12ef09d17fb40ba366d70d9567364c76 449 SMART SM00984 335 431 5.9E-30 T 30-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CL1_0827 12ef09d17fb40ba366d70d9567364c76 449 PIRSF PIRSF000124 20 446 2.8E-75 T 30-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 CL1_0827 12ef09d17fb40ba366d70d9567364c76 449 Gene3D G3DSA:3.40.50.720 5 217 1.1E-58 T 30-10-2018 CL1_0827 12ef09d17fb40ba366d70d9567364c76 449 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 21 427 5.8E-133 T 30-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 CL1_0827 12ef09d17fb40ba366d70d9567364c76 449 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 21 197 6.5E-40 T 30-10-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CL1_0827 12ef09d17fb40ba366d70d9567364c76 449 PIRSF PIRSF500136 10 447 2.4E-146 T 30-10-2018 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 CL1_0827 12ef09d17fb40ba366d70d9567364c76 449 SUPERFAMILY SSF52413 320 442 2.88E-27 T 30-10-2018 IPR036220 UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily Reactome: R-HSA-173599 CL1_0827 12ef09d17fb40ba366d70d9567364c76 449 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 335 431 1.6E-22 T 30-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 CL1_0827 12ef09d17fb40ba366d70d9567364c76 449 Gene3D G3DSA:3.40.50.720 219 448 3.0E-69 T 30-10-2018 CL1_1851 2cc11ddc74156f5a2c7e124adb56f456 695 SUPERFAMILY SSF56784 395 691 8.25E-62 T 30-10-2018 IPR036412 HAD-like superfamily CL1_1851 2cc11ddc74156f5a2c7e124adb56f456 695 PRINTS PR00941 Cadmium-transporting ATPase signature 262 278 1.2E-8 T 30-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CL1_1851 2cc11ddc74156f5a2c7e124adb56f456 695 PRINTS PR00941 Cadmium-transporting ATPase signature 5 14 1.2E-8 T 30-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CL1_1851 2cc11ddc74156f5a2c7e124adb56f456 695 PRINTS PR00941 Cadmium-transporting ATPase signature 109 126 1.2E-8 T 30-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CL1_1851 2cc11ddc74156f5a2c7e124adb56f456 695 PRINTS PR00941 Cadmium-transporting ATPase signature 281 295 1.2E-8 T 30-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CL1_1851 2cc11ddc74156f5a2c7e124adb56f456 695 PRINTS PR00941 Cadmium-transporting ATPase signature 181 201 1.2E-8 T 30-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CL1_1851 2cc11ddc74156f5a2c7e124adb56f456 695 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 147 692 4.5E-180 T 30-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CL1_1851 2cc11ddc74156f5a2c7e124adb56f456 695 SUPERFAMILY SSF81665 147 690 9.15E-14 T 30-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 CL1_1851 2cc11ddc74156f5a2c7e124adb56f456 695 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 169 668 3.7E-82 T 30-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CL1_1851 2cc11ddc74156f5a2c7e124adb56f456 695 SUPERFAMILY SSF55008 3 61 2.62E-9 T 30-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 CL1_1851 2cc11ddc74156f5a2c7e124adb56f456 695 Gene3D G3DSA:2.70.150.20 189 301 3.8E-35 T 30-10-2018 CL1_1851 2cc11ddc74156f5a2c7e124adb56f456 695 Pfam PF00122 E1-E2 ATPase 197 377 4.6E-55 T 30-10-2018 CL1_1851 2cc11ddc74156f5a2c7e124adb56f456 695 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 147 695 1.7E-167 T 30-10-2018 CL1_1851 2cc11ddc74156f5a2c7e124adb56f456 695 Pfam PF00403 Heavy-metal-associated domain 6 57 1.7E-9 T 30-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CL1_1851 2cc11ddc74156f5a2c7e124adb56f456 695 Gene3D G3DSA:3.40.1110.10 408 519 3.3E-84 T 30-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CL1_1851 2cc11ddc74156f5a2c7e124adb56f456 695 Gene3D G3DSA:3.40.50.1000 378 643 3.3E-84 T 30-10-2018 IPR023214 HAD superfamily CL1_1851 2cc11ddc74156f5a2c7e124adb56f456 695 Gene3D G3DSA:3.30.70.100 3 81 9.3E-10 T 30-10-2018 CL1_1851 2cc11ddc74156f5a2c7e124adb56f456 695 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 246 260 2.2E-22 T 30-10-2018 CL1_1851 2cc11ddc74156f5a2c7e124adb56f456 695 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 614 626 2.2E-22 T 30-10-2018 CL1_1851 2cc11ddc74156f5a2c7e124adb56f456 695 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 397 411 2.2E-22 T 30-10-2018 CL1_1851 2cc11ddc74156f5a2c7e124adb56f456 695 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 535 545 2.2E-22 T 30-10-2018 CL1_1851 2cc11ddc74156f5a2c7e124adb56f456 695 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 590 609 2.2E-22 T 30-10-2018 CL1_1851 2cc11ddc74156f5a2c7e124adb56f456 695 Pfam PF00702 haloacid dehalogenase-like hydrolase 395 604 2.9E-40 T 30-10-2018 CL1_1851 2cc11ddc74156f5a2c7e124adb56f456 695 ProSitePatterns PS01047 Heavy-metal-associated domain. 7 35 - T 30-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 CL1_1851 2cc11ddc74156f5a2c7e124adb56f456 695 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 399 405 - T 30-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CL1_1851 2cc11ddc74156f5a2c7e124adb56f456 695 SUPERFAMILY SSF81653 201 296 5.36E-26 T 30-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 CL1_0395 171f2401cb3e654174c1015cac244fe6 345 Gene3D G3DSA:3.40.190.10 136 273 2.9E-103 T 30-10-2018 CL1_0395 171f2401cb3e654174c1015cac244fe6 345 SUPERFAMILY SSF53850 43 336 1.2E-75 T 30-10-2018 CL1_0395 171f2401cb3e654174c1015cac244fe6 345 Gene3D G3DSA:3.40.190.10 45 336 2.9E-103 T 30-10-2018 CL1_0395 171f2401cb3e654174c1015cac244fe6 345 Pfam PF16868 NMT1-like family 45 336 1.1E-86 T 30-10-2018 IPR011852 TRAP transporter solute receptor, TAXI family CL1_0395 171f2401cb3e654174c1015cac244fe6 345 TIGRFAM TIGR02122 TRAP_TAXI: TRAP transporter solute receptor, TAXI family 1 336 2.5E-105 T 30-10-2018 IPR011852 TRAP transporter solute receptor, TAXI family CL1_0043 1605702f0325526d1b786fcdb3174f8f 386 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 6 185 5.2E-44 T 30-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CL1_0043 1605702f0325526d1b786fcdb3174f8f 386 TIGRFAM TIGR00505 ribA: GTP cyclohydrolase II 197 382 8.5E-68 T 30-10-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 CL1_0043 1605702f0325526d1b786fcdb3174f8f 386 Gene3D G3DSA:3.40.50.10990 194 359 3.6E-68 T 30-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 CL1_0043 1605702f0325526d1b786fcdb3174f8f 386 Hamap MF_00179 GTP cyclohydrolase-2 [ribA]. 192 384 37.735 T 30-10-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 CL1_0043 1605702f0325526d1b786fcdb3174f8f 386 SUPERFAMILY SSF142695 193 360 3.92E-58 T 30-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 CL1_0043 1605702f0325526d1b786fcdb3174f8f 386 PIRSF PIRSF001259 1 386 3.4E-127 T 30-10-2018 CL1_0043 1605702f0325526d1b786fcdb3174f8f 386 Gene3D G3DSA:3.90.870.10 3 193 4.4E-45 T 30-10-2018 CL1_0043 1605702f0325526d1b786fcdb3174f8f 386 SUPERFAMILY SSF55821 2 185 2.08E-46 T 30-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily CL1_0043 1605702f0325526d1b786fcdb3174f8f 386 Pfam PF00925 GTP cyclohydrolase II 199 358 8.3E-67 T 30-10-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 CL1_0668 8c811e47e8524034e02a4d6bc423a5c7 249 SUPERFAMILY SSF55666 155 244 3.01E-25 T 30-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CL1_0668 8c811e47e8524034e02a4d6bc423a5c7 249 SUPERFAMILY SSF54211 10 180 3.85E-47 T 30-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CL1_0668 8c811e47e8524034e02a4d6bc423a5c7 249 Hamap MF_00591 Exosome complex component Rrp41 [rrp41]. 6 242 61.23 T 30-10-2018 IPR011807 Exosome complex component Rrp41 GO:0000178|GO:0006401|GO:0016896 CL1_0668 8c811e47e8524034e02a4d6bc423a5c7 249 Pfam PF03725 3' exoribonuclease family, domain 2 157 222 3.4E-16 T 30-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CL1_0668 8c811e47e8524034e02a4d6bc423a5c7 249 TIGRFAM TIGR02065 ECX1: exosome complex exonuclease 1 9 238 1.0E-120 T 30-10-2018 IPR011807 Exosome complex component Rrp41 GO:0000178|GO:0006401|GO:0016896 CL1_0668 8c811e47e8524034e02a4d6bc423a5c7 249 Pfam PF01138 3' exoribonuclease family, domain 1 25 154 2.8E-35 T 30-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CL1_0668 8c811e47e8524034e02a4d6bc423a5c7 249 Gene3D G3DSA:3.30.230.70 24 249 1.0E-77 T 30-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CL1_1640 302de2a0be1ee64c364ec114d20b3b68 165 Gene3D G3DSA:2.20.28.10 119 156 2.9E-19 T 30-10-2018 CL1_1640 302de2a0be1ee64c364ec114d20b3b68 165 Pfam PF17146 PIN domain of ribonuclease 5 87 6.9E-19 T 30-10-2018 IPR033411 Ribonuclease, PIN domain Reactome: R-HSA-6791226 CL1_1640 302de2a0be1ee64c364ec114d20b3b68 165 SUPERFAMILY SSF88723 4 114 9.81E-8 T 30-10-2018 IPR029060 PIN-like domain superfamily CL1_1640 302de2a0be1ee64c364ec114d20b3b68 165 Gene3D G3DSA:3.40.50.1010 1 118 1.2E-40 T 30-10-2018 CL1_0867 ac53523dc2d09a7d52c5492bf27a2fb9 460 Pfam PF01909 Nucleotidyltransferase domain 39 145 3.8E-12 T 30-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 CL1_0867 ac53523dc2d09a7d52c5492bf27a2fb9 460 PIRSF PIRSF005335 6 459 1.9E-152 T 30-10-2018 IPR008229 tRNA nucleotidyltransferase, archaea GO:0001680|GO:0003723|GO:0004810 CL1_0867 ac53523dc2d09a7d52c5492bf27a2fb9 460 Pfam PF09249 tRNA nucleotidyltransferase, second domain 159 282 2.1E-40 T 30-10-2018 IPR015329 tRNA nucleotidyltransferase, substrate binding GO:0004810|GO:0016437 CL1_0867 ac53523dc2d09a7d52c5492bf27a2fb9 460 SUPERFAMILY SSF81301 7 154 2.16E-35 T 30-10-2018 CL1_0867 ac53523dc2d09a7d52c5492bf27a2fb9 460 Gene3D G3DSA:3.30.70.1550 364 403 5.0E-22 T 30-10-2018 CL1_0867 ac53523dc2d09a7d52c5492bf27a2fb9 460 SUPERFAMILY SSF81631 157 283 6.28E-38 T 30-10-2018 CL1_0867 ac53523dc2d09a7d52c5492bf27a2fb9 460 SUPERFAMILY SSF55003 269 453 4.32E-39 T 30-10-2018 IPR011068 Nucleotidyltransferase, class I-like, C-terminal GO:0003723|GO:0016779|GO:0031123 CL1_0867 ac53523dc2d09a7d52c5492bf27a2fb9 460 Hamap MF_01264 CCA-adding enzyme [cca]. 1 460 161.164 T 30-10-2018 IPR008229 tRNA nucleotidyltransferase, archaea GO:0001680|GO:0003723|GO:0004810 CL1_0867 ac53523dc2d09a7d52c5492bf27a2fb9 460 Gene3D G3DSA:3.30.70.590 294 431 5.0E-22 T 30-10-2018 CL1_0867 ac53523dc2d09a7d52c5492bf27a2fb9 460 Gene3D G3DSA:1.10.1410.30 13 282 8.8E-88 T 30-10-2018 CL1_0867 ac53523dc2d09a7d52c5492bf27a2fb9 460 TIGRFAM TIGR03671 cca_archaeal: CCA-adding enzyme 10 422 5.0E-143 T 30-10-2018 IPR008229 tRNA nucleotidyltransferase, archaea GO:0001680|GO:0003723|GO:0004810 CL1_0867 ac53523dc2d09a7d52c5492bf27a2fb9 460 Gene3D G3DSA:3.30.460.10 20 156 8.8E-88 T 30-10-2018 CL1_1464 76566ff7d2da2a479c1868d98963af01 392 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 234 247 - T 30-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 CL1_1464 76566ff7d2da2a479c1868d98963af01 392 Gene3D G3DSA:3.90.1150.10 34 384 7.8E-133 T 30-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 CL1_1464 76566ff7d2da2a479c1868d98963af01 392 SUPERFAMILY SSF53383 10 391 5.65E-121 T 30-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase CL1_1464 76566ff7d2da2a479c1868d98963af01 392 Gene3D G3DSA:3.40.640.10 65 284 7.8E-133 T 30-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 CL1_1464 76566ff7d2da2a479c1868d98963af01 392 Pfam PF00155 Aminotransferase class I and II 34 384 4.6E-77 T 30-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CL1_1349 686015aef589d4cde5e96a824d394ce4 658 Pfam PF04151 Bacterial pre-peptidase C-terminal domain 573 640 7.5E-8 T 30-10-2018 IPR007280 Peptidase, C-terminal, archaeal/bacterial CL1_1349 686015aef589d4cde5e96a824d394ce4 658 SUPERFAMILY SSF52743 150 440 7.33E-90 T 30-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 CL1_1349 686015aef589d4cde5e96a824d394ce4 658 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 165 176 - T 30-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site CL1_1349 686015aef589d4cde5e96a824d394ce4 658 PIRSF PIRSF037907 1 658 0.0 T 30-10-2018 IPR017319 Subtilisin-like serine protease TK1689-type CL1_1349 686015aef589d4cde5e96a824d394ce4 658 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 202 212 - T 30-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site CL1_1349 686015aef589d4cde5e96a824d394ce4 658 PRINTS PR00723 Subtilisin serine protease family (S8) signature 160 179 2.4E-21 T 30-10-2018 IPR015500 Peptidase S8, subtilisin-related CL1_1349 686015aef589d4cde5e96a824d394ce4 658 PRINTS PR00723 Subtilisin serine protease family (S8) signature 379 395 2.4E-21 T 30-10-2018 IPR015500 Peptidase S8, subtilisin-related CL1_1349 686015aef589d4cde5e96a824d394ce4 658 PRINTS PR00723 Subtilisin serine protease family (S8) signature 198 211 2.4E-21 T 30-10-2018 IPR015500 Peptidase S8, subtilisin-related CL1_1349 686015aef589d4cde5e96a824d394ce4 658 SUPERFAMILY SSF49785 452 527 3.4E-5 T 30-10-2018 IPR008979 Galactose-binding-like domain superfamily CL1_1349 686015aef589d4cde5e96a824d394ce4 658 Gene3D G3DSA:3.30.70.80 38 130 6.4E-40 T 30-10-2018 IPR037045 Peptidase S8 propeptide/proteinase inhibitor I9 superfamily Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 CL1_1349 686015aef589d4cde5e96a824d394ce4 658 Pfam PF00082 Subtilase family 160 431 1.2E-65 T 30-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CL1_1349 686015aef589d4cde5e96a824d394ce4 658 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 380 390 - T 30-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site CL1_1349 686015aef589d4cde5e96a824d394ce4 658 Gene3D G3DSA:2.60.120.380 445 544 1.6E-21 T 30-10-2018 CL1_1349 686015aef589d4cde5e96a824d394ce4 658 Gene3D G3DSA:2.60.120.380 558 655 1.4E-14 T 30-10-2018 CL1_1349 686015aef589d4cde5e96a824d394ce4 658 Gene3D G3DSA:3.40.50.200 131 443 8.0E-138 T 30-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 CL1_1058 16cadd35fd750366321db62229f67d93 415 SUPERFAMILY SSF46785 297 403 1.09E-30 T 30-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CL1_1058 16cadd35fd750366321db62229f67d93 415 SMART SM01074 312 393 3.1E-34 T 30-10-2018 IPR015163 Cdc6, C-terminal Reactome: R-HSA-176187|Reactome: R-HSA-539107|Reactome: R-HSA-68689|Reactome: R-HSA-68827|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962 CL1_1058 16cadd35fd750366321db62229f67d93 415 Hamap MF_01407 ORC1-type DNA replication protein. 12 394 34.201 T 30-10-2018 IPR014277 Orc1/Cdc6-type DNA replication protein, archaea CL1_1058 16cadd35fd750366321db62229f67d93 415 SMART SM00382 57 218 6.6E-12 T 30-10-2018 IPR003593 AAA+ ATPase domain CL1_1058 16cadd35fd750366321db62229f67d93 415 Pfam PF13191 AAA ATPase domain 35 175 1.2E-9 T 30-10-2018 CL1_1058 16cadd35fd750366321db62229f67d93 415 TIGRFAM TIGR02928 TIGR02928: orc1/cdc6 family replication initiation protein 19 383 2.4E-149 T 30-10-2018 IPR014277 Orc1/Cdc6-type DNA replication protein, archaea CL1_1058 16cadd35fd750366321db62229f67d93 415 SUPERFAMILY SSF52540 19 291 2.18E-55 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_1058 16cadd35fd750366321db62229f67d93 415 Gene3D G3DSA:1.10.8.60 19 295 4.0E-109 T 30-10-2018 CL1_1058 16cadd35fd750366321db62229f67d93 415 Pfam PF09079 CDC6, C terminal winged helix domain 312 391 1.7E-25 T 30-10-2018 IPR015163 Cdc6, C-terminal Reactome: R-HSA-176187|Reactome: R-HSA-539107|Reactome: R-HSA-68689|Reactome: R-HSA-68827|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962 CL1_1058 16cadd35fd750366321db62229f67d93 415 Gene3D G3DSA:3.40.50.300 35 216 4.0E-109 T 30-10-2018 CL1_1058 16cadd35fd750366321db62229f67d93 415 Gene3D G3DSA:1.10.10.10 304 405 1.2E-32 T 30-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CL1_1367 da0b93138c7b9945bc03d3143c80435f 168 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 74 85 - T 30-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CL1_1367 da0b93138c7b9945bc03d3143c80435f 168 Pfam PF00037 4Fe-4S binding domain 67 88 2.3E-7 T 30-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CL1_1367 da0b93138c7b9945bc03d3143c80435f 168 Gene3D G3DSA:3.30.70.20 36 106 1.2E-12 T 30-10-2018 CL1_1367 da0b93138c7b9945bc03d3143c80435f 168 SUPERFAMILY SSF54862 4 137 1.13E-19 T 30-10-2018 CL1_1306 45f5c6656fc27e7c88e42584c9cb71e3 338 Pfam PF01032 FecCD transport family 13 330 3.1E-83 T 30-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 CL1_1306 45f5c6656fc27e7c88e42584c9cb71e3 338 SUPERFAMILY SSF81345 3 330 1.96E-75 T 30-10-2018 IPR037294 ABC transporter, BtuC-like CL1_1306 45f5c6656fc27e7c88e42584c9cb71e3 338 Gene3D G3DSA:1.10.3470.10 2 335 6.7E-92 T 30-10-2018 IPR037294 ABC transporter, BtuC-like CL1_0966 1f18af6eb24d909f41de2a7f916c0af9 185 SMART SM00116 55 102 7.9E-6 T 30-10-2018 IPR000644 CBS domain CL1_0966 1f18af6eb24d909f41de2a7f916c0af9 185 SMART SM00116 133 181 5.4E-9 T 30-10-2018 IPR000644 CBS domain CL1_0966 1f18af6eb24d909f41de2a7f916c0af9 185 SUPERFAMILY SSF54631 36 180 9.21E-30 T 30-10-2018 CL1_0966 1f18af6eb24d909f41de2a7f916c0af9 185 Pfam PF00571 CBS domain 126 180 3.7E-14 T 30-10-2018 IPR000644 CBS domain CL1_0966 1f18af6eb24d909f41de2a7f916c0af9 185 Pfam PF00571 CBS domain 51 100 3.0E-11 T 30-10-2018 IPR000644 CBS domain CL1_0966 1f18af6eb24d909f41de2a7f916c0af9 185 Gene3D G3DSA:3.10.580.10 103 182 4.8E-16 T 30-10-2018 CL1_0966 1f18af6eb24d909f41de2a7f916c0af9 185 Gene3D G3DSA:3.10.580.10 4 102 9.1E-14 T 30-10-2018 CL1_1211 910b911603537b7b78b3a3b007359891 568 SUPERFAMILY SSF52141 265 421 1.57E-40 T 30-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CL1_1211 910b911603537b7b78b3a3b007359891 568 TIGRFAM TIGR00451 unchar_dom_2: uncharacterized domain 2 511 565 2.0E-8 T 30-10-2018 IPR004521 Uncharacterised domain CHP00451 GO:0003723 CL1_1211 910b911603537b7b78b3a3b007359891 568 Gene3D G3DSA:2.30.130.10 502 568 1.0E-23 T 30-10-2018 IPR036974 PUA domain superfamily GO:0003723 CL1_1211 910b911603537b7b78b3a3b007359891 568 Gene3D G3DSA:3.40.50.10630 252 423 5.5E-47 T 30-10-2018 CL1_1211 910b911603537b7b78b3a3b007359891 568 SUPERFAMILY SSF51713 1 243 2.46E-20 T 30-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CL1_1211 910b911603537b7b78b3a3b007359891 568 SUPERFAMILY SSF88697 511 566 3.59E-13 T 30-10-2018 IPR015947 PUA-like superfamily CL1_1211 910b911603537b7b78b3a3b007359891 568 SUPERFAMILY SSF88802 248 500 1.24E-16 T 30-10-2018 CL1_1211 910b911603537b7b78b3a3b007359891 568 Pfam PF14810 Patch-forming domain C2 of tRNA-guanine transglycosylase 438 500 2.2E-6 T 30-10-2018 IPR029402 tRNA-guanine transglycosylase, patch-forming domain C2 MetaCyc: PWY-6711|MetaCyc: PWY-7923 CL1_1211 910b911603537b7b78b3a3b007359891 568 SMART SM00359 502 568 1.1E-7 T 30-10-2018 IPR002478 PUA domain GO:0003723 CL1_1211 910b911603537b7b78b3a3b007359891 568 Pfam PF01472 PUA domain 511 566 3.5E-11 T 30-10-2018 IPR002478 PUA domain GO:0003723 CL1_1487 241e052b98ee01caed18bc06225f4078 444 SUPERFAMILY SSF54966 3 137 1.07E-38 T 30-10-2018 IPR036422 RuBisCO large subunit, N-terminal domain superfamily GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 CL1_1487 241e052b98ee01caed18bc06225f4078 444 TIGRFAM TIGR03326 rubisco_III: ribulose bisphosphate carboxylase, type III 11 438 1.4E-221 T 30-10-2018 IPR017712 Ribulose bisphosphate carboxylase, type III GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 CL1_1487 241e052b98ee01caed18bc06225f4078 444 SUPERFAMILY SSF51649 136 441 3.53E-107 T 30-10-2018 IPR036376 Ribulose bisphosphate carboxylase, large subunit, C-terminal domain superfamily GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 CL1_1487 241e052b98ee01caed18bc06225f4078 444 Gene3D G3DSA:3.20.20.110 137 438 2.1E-126 T 30-10-2018 IPR036376 Ribulose bisphosphate carboxylase, large subunit, C-terminal domain superfamily GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 CL1_1487 241e052b98ee01caed18bc06225f4078 444 Pfam PF02788 Ribulose bisphosphate carboxylase large chain, N-terminal domain 12 131 1.2E-45 T 30-10-2018 IPR017443 Ribulose bisphosphate carboxylase, large subunit, ferrodoxin-like N-terminal GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 CL1_1487 241e052b98ee01caed18bc06225f4078 444 Hamap MF_01133 Ribulose bisphosphate carboxylase [rbcL]. 10 439 52.89 T 30-10-2018 IPR017712 Ribulose bisphosphate carboxylase, type III GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 CL1_1487 241e052b98ee01caed18bc06225f4078 444 Pfam PF00016 Ribulose bisphosphate carboxylase large chain, catalytic domain 142 438 1.3E-95 T 30-10-2018 IPR000685 Ribulose bisphosphate carboxylase, large subunit, C-terminal GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 CL1_1487 241e052b98ee01caed18bc06225f4078 444 Gene3D G3DSA:3.30.70.150 1 136 4.5E-46 T 30-10-2018 IPR036422 RuBisCO large subunit, N-terminal domain superfamily GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 CL1_1646 79883ea06478a54339ab5fb6cd47598b 269 Pfam PF01889 Membrane protein of unknown function DUF63 4 268 6.7E-85 T 30-10-2018 IPR002749 Protein of unknown function DUF63 CL1_0930 34cbdd63ecf3495547c025940cec282e 585 SUPERFAMILY SSF47917 447 551 1.07E-26 T 30-10-2018 CL1_0930 34cbdd63ecf3495547c025940cec282e 585 Hamap MF_00309 V-type ATP synthase alpha chain [atpA]. 1 583 54.974 T 30-10-2018 IPR022878 V-type ATP synthase catalytic alpha chain GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 CL1_0930 34cbdd63ecf3495547c025940cec282e 585 SUPERFAMILY SSF50615 1 68 1.57E-13 T 30-10-2018 IPR036121 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 CL1_0930 34cbdd63ecf3495547c025940cec282e 585 SUPERFAMILY SSF52540 163 439 2.94E-85 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_0930 34cbdd63ecf3495547c025940cec282e 585 Gene3D G3DSA:3.40.50.300 70 434 4.8E-186 T 30-10-2018 CL1_0930 34cbdd63ecf3495547c025940cec282e 585 TIGRFAM TIGR01043 ATP_syn_A_arch: ATP synthase archaeal, A subunit 1 580 0.0 T 30-10-2018 IPR005726 ATP synthase alpha chain, archaea GO:0015986|GO:0033178|GO:0046961 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 CL1_0930 34cbdd63ecf3495547c025940cec282e 585 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 211 434 8.4E-93 T 30-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 CL1_0930 34cbdd63ecf3495547c025940cec282e 585 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 425 434 - T 30-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 CL1_0930 34cbdd63ecf3495547c025940cec282e 585 Gene3D G3DSA:1.10.1140.10 435 585 1.0E-60 T 30-10-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 CL1_0930 34cbdd63ecf3495547c025940cec282e 585 Gene3D G3DSA:2.40.30.20 1 69 8.7E-30 T 30-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 CL1_0930 34cbdd63ecf3495547c025940cec282e 585 SMART SM00382 223 411 0.0016 T 30-10-2018 IPR003593 AAA+ ATPase domain CL1_0930 34cbdd63ecf3495547c025940cec282e 585 Pfam PF16886 ATPsynthase alpha/beta subunit N-term extension 82 202 1.2E-48 T 30-10-2018 IPR031686 ATPsynthase alpha/beta subunit, N-terminal extension KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 CL1_0930 34cbdd63ecf3495547c025940cec282e 585 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 4 66 9.0E-15 T 30-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 CL1_0930 34cbdd63ecf3495547c025940cec282e 585 Gene3D G3DSA:2.40.50.100 113 184 4.8E-186 T 30-10-2018 CL1_1106 c451c5e9696459604ae30116cd21eeea 184 Gene3D G3DSA:3.90.950.10 1 184 3.1E-74 T 30-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like CL1_1106 c451c5e9696459604ae30116cd21eeea 184 Pfam PF01725 Ham1 family 3 178 2.1E-52 T 30-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 CL1_1106 c451c5e9696459604ae30116cd21eeea 184 SUPERFAMILY SSF52972 1 182 6.54E-64 T 30-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like CL1_1106 c451c5e9696459604ae30116cd21eeea 184 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 3 179 1.4E-64 T 30-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 CL1_1106 c451c5e9696459604ae30116cd21eeea 184 Hamap MF_01405 dITP/XTP pyrophosphatase. 1 181 42.854 T 30-10-2018 IPR020922 dITP/XTP pyrophosphatase GO:0009143|GO:0017111 KEGG: 00230+3.6.1.66 CL1_0840 05075fe1e2a2491b4a27f086f7b5e6b0 331 SUPERFAMILY SSF53448 1 286 2.23E-55 T 30-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases CL1_0840 05075fe1e2a2491b4a27f086f7b5e6b0 331 Gene3D G3DSA:2.160.10.10 239 329 2.0E-8 T 30-10-2018 CL1_0840 05075fe1e2a2491b4a27f086f7b5e6b0 331 Gene3D G3DSA:3.90.550.10 1 238 8.0E-55 T 30-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases CL1_0840 05075fe1e2a2491b4a27f086f7b5e6b0 331 Pfam PF00483 Nucleotidyl transferase 4 233 4.9E-38 T 30-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 CL1_0792 ac6e4a8afc7e11226900d076f74b9d15 231 Gene3D G3DSA:3.30.200.20 17 227 8.7E-96 T 30-10-2018 CL1_0792 ac6e4a8afc7e11226900d076f74b9d15 231 SUPERFAMILY SSF56104 3 230 7.52E-82 T 30-10-2018 CL1_0792 ac6e4a8afc7e11226900d076f74b9d15 231 ProSitePatterns PS01057 SAICAR synthetase signature 1. 81 95 - T 30-10-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CL1_0792 ac6e4a8afc7e11226900d076f74b9d15 231 Gene3D G3DSA:3.30.470.20 80 215 8.7E-96 T 30-10-2018 CL1_0792 ac6e4a8afc7e11226900d076f74b9d15 231 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 2 226 1.5E-76 T 30-10-2018 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 CL1_0792 ac6e4a8afc7e11226900d076f74b9d15 231 Pfam PF01259 SAICAR synthetase 3 223 2.5E-68 T 30-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CL1_0792 ac6e4a8afc7e11226900d076f74b9d15 231 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 1 229 32.084 T 30-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CL1_0792 ac6e4a8afc7e11226900d076f74b9d15 231 ProSitePatterns PS01058 SAICAR synthetase signature 2. 167 175 - T 30-10-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CL1_1407 d9ba3fc2c1e768f6a1b32133316bafc6 171 Gene3D G3DSA:3.40.630.30 1 128 2.2E-44 T 30-10-2018 CL1_1407 d9ba3fc2c1e768f6a1b32133316bafc6 171 SUPERFAMILY SSF55729 7 124 4.99E-29 T 30-10-2018 IPR016181 Acyl-CoA N-acyltransferase CL1_1407 d9ba3fc2c1e768f6a1b32133316bafc6 171 Pfam PF00583 Acetyltransferase (GNAT) family 13 111 6.5E-21 T 30-10-2018 IPR000182 GNAT domain CL1_0445 76caf095d0eb8849ecc7d31dfb1d2a61 147 SUPERFAMILY SSF50249 23 147 4.88E-37 T 30-10-2018 IPR012340 Nucleic acid-binding, OB-fold CL1_0445 76caf095d0eb8849ecc7d31dfb1d2a61 147 Hamap MF_00403_A 30S ribosomal protein S12 [rpsL]. 1 147 44.994 T 30-10-2018 IPR022863 Ribosomal protein S12, archaea CL1_0445 76caf095d0eb8849ecc7d31dfb1d2a61 147 PRINTS PR01034 Ribosomal protein S12 signature 47 62 9.7E-5 T 30-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CL1_0445 76caf095d0eb8849ecc7d31dfb1d2a61 147 PRINTS PR01034 Ribosomal protein S12 signature 79 98 9.7E-5 T 30-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CL1_0445 76caf095d0eb8849ecc7d31dfb1d2a61 147 PRINTS PR01034 Ribosomal protein S12 signature 62 77 9.7E-5 T 30-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CL1_0445 76caf095d0eb8849ecc7d31dfb1d2a61 147 ProSitePatterns PS00055 Ribosomal protein S12 signature. 63 70 - T 30-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CL1_0445 76caf095d0eb8849ecc7d31dfb1d2a61 147 TIGRFAM TIGR00982 uS12_E_A: ribosomal protein uS12 9 147 1.1E-81 T 30-10-2018 IPR005680 Ribosomal protein S23, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0445 76caf095d0eb8849ecc7d31dfb1d2a61 147 Pfam PF00164 Ribosomal protein S12/S23 32 146 7.5E-51 T 30-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CL1_0445 76caf095d0eb8849ecc7d31dfb1d2a61 147 Gene3D G3DSA:2.40.50.140 28 147 1.1E-51 T 30-10-2018 CL1_0445 76caf095d0eb8849ecc7d31dfb1d2a61 147 PIRSF PIRSF002133 19 147 2.2E-37 T 30-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CL1_1686 6aa3b6160ff03e5520ac4e85fbf3d6e0 612 Gene3D G3DSA:1.10.3720.10 330 599 6.6E-36 T 30-10-2018 IPR035906 MetI-like superfamily CL1_1686 6aa3b6160ff03e5520ac4e85fbf3d6e0 612 SUPERFAMILY SSF161098 333 605 9.35E-41 T 30-10-2018 IPR035906 MetI-like superfamily CL1_1686 6aa3b6160ff03e5520ac4e85fbf3d6e0 612 SUPERFAMILY SSF161098 24 312 5.79E-43 T 30-10-2018 IPR035906 MetI-like superfamily CL1_1686 6aa3b6160ff03e5520ac4e85fbf3d6e0 612 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 116 305 2.1E-12 T 30-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 CL1_1686 6aa3b6160ff03e5520ac4e85fbf3d6e0 612 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 417 601 1.3E-16 T 30-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 CL1_1686 6aa3b6160ff03e5520ac4e85fbf3d6e0 612 Gene3D G3DSA:1.10.3720.10 19 319 1.5E-49 T 30-10-2018 IPR035906 MetI-like superfamily CL1_0036 98b11489db26ff6fed513fca89868369 250 TIGRFAM TIGR00292 TIGR00292: thiazole biosynthesis enzyme 4 249 1.1E-90 T 30-10-2018 IPR002922 Thiazole biosynthetic enzyme Thi4 family CL1_0036 98b11489db26ff6fed513fca89868369 250 PRINTS PR00419 Adrenodoxin reductase family signature 49 62 8.2E-7 T 30-10-2018 CL1_0036 98b11489db26ff6fed513fca89868369 250 PRINTS PR00419 Adrenodoxin reductase family signature 26 48 8.2E-7 T 30-10-2018 CL1_0036 98b11489db26ff6fed513fca89868369 250 Pfam PF01946 Thi4 family 8 231 9.2E-77 T 30-10-2018 CL1_0036 98b11489db26ff6fed513fca89868369 250 SUPERFAMILY SSF51905 3 242 5.18E-45 T 30-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily CL1_0036 98b11489db26ff6fed513fca89868369 250 Hamap MF_00304 Thiamine thiazole synthase [thi4]. 2 250 43.975 T 30-10-2018 IPR022828 Thiazole biosynthetic enzyme, prokaryotic CL1_0036 98b11489db26ff6fed513fca89868369 250 Gene3D G3DSA:3.50.50.60 1 250 1.7E-98 T 30-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily CL1_0557 1d11c590ac5b7f179c8def7e28a20fa7 356 SUPERFAMILY SSF53092 2 129 1.74E-17 T 30-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal CL1_0557 1d11c590ac5b7f179c8def7e28a20fa7 356 SUPERFAMILY SSF55920 132 356 1.7E-76 T 30-10-2018 IPR036005 Creatinase/aminopeptidase-like CL1_0557 1d11c590ac5b7f179c8def7e28a20fa7 356 Gene3D G3DSA:3.90.230.10 132 355 2.1E-83 T 30-10-2018 CL1_0557 1d11c590ac5b7f179c8def7e28a20fa7 356 Gene3D G3DSA:3.40.350.10 1 129 9.1E-34 T 30-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal CL1_0557 1d11c590ac5b7f179c8def7e28a20fa7 356 Pfam PF00557 Metallopeptidase family M24 138 338 8.6E-69 T 30-10-2018 IPR000994 Peptidase M24 CL1_0557 1d11c590ac5b7f179c8def7e28a20fa7 356 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 286 298 - T 30-10-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site CL1_0557 1d11c590ac5b7f179c8def7e28a20fa7 356 Pfam PF01321 Creatinase/Prolidase N-terminal domain 2 130 1.5E-19 T 30-10-2018 IPR000587 Creatinase, N-terminal GO:0016787 CL1_1506 dc33f9b63aff4c7fd9987efe3d001b9d 185 Pfam PF01926 50S ribosome-binding GTPase 3 136 4.3E-23 T 30-10-2018 IPR006073 GTP binding domain GO:0005525 CL1_1506 dc33f9b63aff4c7fd9987efe3d001b9d 185 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 2 175 1.0E-20 T 30-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CL1_1506 dc33f9b63aff4c7fd9987efe3d001b9d 185 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 88 106 5.9E-8 T 30-10-2018 IPR006073 GTP binding domain GO:0005525 CL1_1506 dc33f9b63aff4c7fd9987efe3d001b9d 185 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 4 24 5.9E-8 T 30-10-2018 IPR006073 GTP binding domain GO:0005525 CL1_1506 dc33f9b63aff4c7fd9987efe3d001b9d 185 SUPERFAMILY SSF52540 2 182 2.11E-37 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_1506 dc33f9b63aff4c7fd9987efe3d001b9d 185 Gene3D G3DSA:3.40.50.300 1 181 4.0E-38 T 30-10-2018 CL1_0917 baa53421189fc4f32c6a2bcadb2b63fb 805 Gene3D G3DSA:3.40.190.10 57 154 2.3E-18 T 30-10-2018 CL1_0917 baa53421189fc4f32c6a2bcadb2b63fb 805 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 776 805 4.9E-4 T 30-10-2018 CL1_0917 baa53421189fc4f32c6a2bcadb2b63fb 805 Gene3D G3DSA:3.10.105.10 155 364 2.3E-18 T 30-10-2018 CL1_0917 baa53421189fc4f32c6a2bcadb2b63fb 805 SUPERFAMILY SSF53850 45 376 5.07E-22 T 30-10-2018 CL1_0917 baa53421189fc4f32c6a2bcadb2b63fb 805 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 55 365 3.7E-18 T 30-10-2018 IPR000914 Solute-binding protein family 5 domain CL1_0074 34b590d757bf54e29d97a0fc1dcaba5b 1350 SUPERFAMILY SSF82866 1111 1343 9.94E-20 T 30-10-2018 CL1_0074 34b590d757bf54e29d97a0fc1dcaba5b 1350 SUPERFAMILY SSF82866 762 963 2.22E-24 T 30-10-2018 CL1_0074 34b590d757bf54e29d97a0fc1dcaba5b 1350 Pfam PF03176 MMPL family 750 974 5.5E-35 T 30-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 CL1_0074 34b590d757bf54e29d97a0fc1dcaba5b 1350 Pfam PF03176 MMPL family 1050 1343 5.6E-31 T 30-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 CL1_0412 6d5a2b278ce96c88a35d2389152e3d9c 830 Gene3D G3DSA:3.40.50.2000 269 405 1.8E-8 T 30-10-2018 CL1_0412 6d5a2b278ce96c88a35d2389152e3d9c 830 Pfam PF11897 Protein of unknown function (DUF3417) 15 122 7.0E-32 T 30-10-2018 IPR024517 Glycogen phosphorylase, domain of unknown function DUF3417 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238 CL1_0412 6d5a2b278ce96c88a35d2389152e3d9c 830 TIGRFAM TIGR02094 more_P_ylases: alpha-glucan phosphorylases 109 691 2.5E-254 T 30-10-2018 IPR011834 Alpha-glucan phosphorylase GO:0004645|GO:0005975|GO:0030170 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238 CL1_0412 6d5a2b278ce96c88a35d2389152e3d9c 830 ProSitePatterns PS00102 Phosphorylase pyridoxal-phosphate attachment site. 585 597 - T 30-10-2018 IPR035090 Phosphorylase pyridoxal-phosphate attachment site KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 CL1_0412 6d5a2b278ce96c88a35d2389152e3d9c 830 Gene3D G3DSA:3.40.50.2000 406 706 1.5E-42 T 30-10-2018 CL1_0412 6d5a2b278ce96c88a35d2389152e3d9c 830 Pfam PF00343 Carbohydrate phosphorylase 126 175 7.3E-5 T 30-10-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 CL1_0412 6d5a2b278ce96c88a35d2389152e3d9c 830 Pfam PF00343 Carbohydrate phosphorylase 272 338 4.4E-5 T 30-10-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 CL1_0412 6d5a2b278ce96c88a35d2389152e3d9c 830 Pfam PF00343 Carbohydrate phosphorylase 349 611 2.1E-20 T 30-10-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 CL1_0412 6d5a2b278ce96c88a35d2389152e3d9c 830 PIRSF PIRSF000460 2 766 8.5E-277 T 30-10-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 CL1_0412 6d5a2b278ce96c88a35d2389152e3d9c 830 SUPERFAMILY SSF53756 16 724 6.28E-206 T 30-10-2018 CL1_0412 6d5a2b278ce96c88a35d2389152e3d9c 830 Gene3D G3DSA:3.40.50.2000 116 185 4.0E-11 T 30-10-2018 CL1_0072 f0c9a862b4f13e278ca612729f7c3c32 339 SUPERFAMILY SSF53187 2 335 3.41E-48 T 30-10-2018 CL1_0072 f0c9a862b4f13e278ca612729f7c3c32 339 SUPERFAMILY SSF101821 67 178 1.4E-25 T 30-10-2018 CL1_0072 f0c9a862b4f13e278ca612729f7c3c32 339 PIRSF PIRSF001123 1 339 4.5E-35 T 30-10-2018 IPR008007 Peptidase M42 CL1_0072 f0c9a862b4f13e278ca612729f7c3c32 339 Gene3D G3DSA:3.40.630.10 11 333 1.5E-109 T 30-10-2018 CL1_0072 f0c9a862b4f13e278ca612729f7c3c32 339 Pfam PF05343 M42 glutamyl aminopeptidase 49 328 4.1E-68 T 30-10-2018 IPR008007 Peptidase M42 CL1_0072 f0c9a862b4f13e278ca612729f7c3c32 339 Gene3D G3DSA:2.40.30.40 70 164 1.5E-109 T 30-10-2018 IPR023367 Peptidase M42, domain 2 CL1_0255 0e1ebe8c5ef47b1a6716d3c432b68486 464 Pfam PF03008 Archaea bacterial proteins of unknown function 318 416 1.3E-29 T 30-10-2018 IPR004256 Domain of unknown function DUF234, DEXX-box ATPase C-terminal CL1_0255 0e1ebe8c5ef47b1a6716d3c432b68486 464 Gene3D G3DSA:3.40.50.300 16 180 1.2E-28 T 30-10-2018 CL1_0255 0e1ebe8c5ef47b1a6716d3c432b68486 464 SUPERFAMILY SSF52540 13 251 4.75E-34 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_0255 0e1ebe8c5ef47b1a6716d3c432b68486 464 Pfam PF01637 ATPase domain predominantly from Archaea 20 211 2.9E-20 T 30-10-2018 IPR011579 ATPase domain GO:0005524 CL1_1710 9da8dc2eeb0749b00563a5792ab93dc7 310 Gene3D G3DSA:1.20.1420.30 35 296 1.4E-80 T 30-10-2018 CL1_1710 9da8dc2eeb0749b00563a5792ab93dc7 310 Pfam PF01699 Sodium/calcium exchanger protein 165 303 4.9E-25 T 30-10-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 CL1_1710 9da8dc2eeb0749b00563a5792ab93dc7 310 Pfam PF01699 Sodium/calcium exchanger protein 5 143 4.2E-25 T 30-10-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 CL1_1710 9da8dc2eeb0749b00563a5792ab93dc7 310 Gene3D G3DSA:1.20.58.1130 8 195 1.4E-80 T 30-10-2018 CL1_1710 9da8dc2eeb0749b00563a5792ab93dc7 310 TIGRFAM TIGR00367 TIGR00367: K+-dependent Na+/Ca+ exchanger homolog 3 298 5.0E-61 T 30-10-2018 IPR004481 Sodium/potassium/calcium exchanger Reactome: R-HSA-425561 CL1_1179 4ccbaa421b1012d549a9f48f66120a02 188 Pfam PF04407 Protein of unknown function (DUF531) 3 171 8.1E-77 T 30-10-2018 IPR007501 Protein of unknown function DUF531 CL1_1179 4ccbaa421b1012d549a9f48f66120a02 188 PIRSF PIRSF006006 1 180 1.3E-84 T 30-10-2018 IPR007501 Protein of unknown function DUF531 CL1_0547 c552854a2ca2ac1165955c4e91a78ea7 649 Gene3D G3DSA:2.30.310.10 5 150 4.4E-32 T 30-10-2018 CL1_0547 c552854a2ca2ac1165955c4e91a78ea7 649 Pfam PF05670 Domain of unknown function (DUF814) 454 552 1.1E-25 T 30-10-2018 IPR008532 Domain of unknown function DUF814 CL1_0547 c552854a2ca2ac1165955c4e91a78ea7 649 Pfam PF05833 Fibronectin-binding protein A N-terminus (FbpA) 7 434 9.4E-82 T 30-10-2018 CL1_0547 c552854a2ca2ac1165955c4e91a78ea7 649 SUPERFAMILY SSF46946 172 221 8.95E-5 T 30-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 CL1_0039 d8bc12dd6a306184e41c7a5c7e9c1c01 219 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 1 219 19.361 T 30-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CL1_0039 d8bc12dd6a306184e41c7a5c7e9c1c01 219 ProSitePatterns PS01058 SAICAR synthetase signature 2. 175 183 - T 30-10-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CL1_0039 d8bc12dd6a306184e41c7a5c7e9c1c01 219 SUPERFAMILY SSF56104 2 206 2.84E-49 T 30-10-2018 CL1_0039 d8bc12dd6a306184e41c7a5c7e9c1c01 219 Gene3D G3DSA:3.30.470.20 87 205 4.2E-58 T 30-10-2018 CL1_0039 d8bc12dd6a306184e41c7a5c7e9c1c01 219 Pfam PF01259 SAICAR synthetase 4 203 4.6E-32 T 30-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CL1_0039 d8bc12dd6a306184e41c7a5c7e9c1c01 219 Gene3D G3DSA:3.30.200.20 4 86 4.2E-58 T 30-10-2018 CL1_1587 5717e62eb92f75302b4e4cde87119c08 464 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 158 295 3.2E-56 T 30-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain CL1_1587 5717e62eb92f75302b4e4cde87119c08 464 TIGRFAM TIGR02717 AcCoA-syn-alpha: acetyl coenzyme A synthetase (ADP forming), alpha domain 5 454 4.1E-186 T 30-10-2018 IPR014089 Acetate-CoA ligase [ADP-forming], alpha domain KEGG: 00010+6.2.1.13|KEGG: 00620+6.2.1.13|KEGG: 00640+6.2.1.13|MetaCyc: PWY-5483|MetaCyc: PWY-5535 CL1_1587 5717e62eb92f75302b4e4cde87119c08 464 SUPERFAMILY SSF52210 138 297 6.15E-45 T 30-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CL1_1587 5717e62eb92f75302b4e4cde87119c08 464 Gene3D G3DSA:3.40.50.720 2 136 1.6E-45 T 30-10-2018 CL1_1587 5717e62eb92f75302b4e4cde87119c08 464 Gene3D G3DSA:3.40.50.261 299 463 6.4E-50 T 30-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CL1_1587 5717e62eb92f75302b4e4cde87119c08 464 SUPERFAMILY SSF52210 301 458 1.44E-32 T 30-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CL1_1587 5717e62eb92f75302b4e4cde87119c08 464 Gene3D G3DSA:3.40.50.261 137 298 1.2E-64 T 30-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CL1_1587 5717e62eb92f75302b4e4cde87119c08 464 SUPERFAMILY SSF51735 5 136 5.9E-37 T 30-10-2018 IPR036291 NAD(P)-binding domain superfamily CL1_1587 5717e62eb92f75302b4e4cde87119c08 464 Pfam PF13380 CoA binding domain 12 141 6.0E-22 T 30-10-2018 IPR003781 CoA-binding GO:0048037 CL1_1587 5717e62eb92f75302b4e4cde87119c08 464 SMART SM00881 8 107 1.0E-37 T 30-10-2018 IPR003781 CoA-binding GO:0048037 CL1_0462 c6d7c6b64c30511ae7775e88904112d5 191 Gene3D G3DSA:1.10.1760.20 1 184 7.2E-57 T 30-10-2018 CL1_0462 c6d7c6b64c30511ae7775e88904112d5 191 Pfam PF01891 Cobalt uptake substrate-specific transmembrane region 1 182 1.1E-54 T 30-10-2018 IPR002751 Metal transport protein CbiM/NikMN GO:0000041|GO:0016021 CL1_0329 eb0bf893f5c149d095e61d5a37f49282 272 SUPERFAMILY SSF51717 6 269 2.49E-80 T 30-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CL1_0329 eb0bf893f5c149d095e61d5a37f49282 272 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 13 266 1.3E-69 T 30-10-2018 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 CL1_0329 eb0bf893f5c149d095e61d5a37f49282 272 Pfam PF00809 Pterin binding enzyme 14 252 1.1E-60 T 30-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CL1_0329 eb0bf893f5c149d095e61d5a37f49282 272 Gene3D G3DSA:3.20.20.20 1 271 1.7E-88 T 30-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CL1_0614 9131bf7918852c6d794f5ca8aab72c32 183 PIRSF PIRSF002161 2 180 2.2E-55 T 30-10-2018 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0614 9131bf7918852c6d794f5ca8aab72c32 183 Gene3D G3DSA:3.30.1440.10 10 182 2.0E-71 T 30-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0614 9131bf7918852c6d794f5ca8aab72c32 183 Hamap MF_01333_A 50S ribosomal protein L5 [rplE]. 14 181 42.338 T 30-10-2018 IPR022804 Ribosomal protein L5, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 CL1_0614 9131bf7918852c6d794f5ca8aab72c32 183 Pfam PF00673 ribosomal L5P family C-terminus 72 171 9.0E-27 T 30-10-2018 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0614 9131bf7918852c6d794f5ca8aab72c32 183 Pfam PF00281 Ribosomal protein L5 16 68 1.0E-18 T 30-10-2018 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0614 9131bf7918852c6d794f5ca8aab72c32 183 SUPERFAMILY SSF55282 15 180 4.0E-56 T 30-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0156 a70dbc43784aea598a6cb9c1d78d0783 104 PIRSF PIRSF029904 1 102 4.9E-33 T 30-10-2018 IPR012359 NTP pyrophosphohydrolase MazG-related, YpjD CL1_0156 a70dbc43784aea598a6cb9c1d78d0783 104 Gene3D G3DSA:1.10.287.1080 1 103 2.4E-26 T 30-10-2018 CL1_0156 a70dbc43784aea598a6cb9c1d78d0783 104 SUPERFAMILY SSF101386 1 95 6.87E-23 T 30-10-2018 CL1_0156 a70dbc43784aea598a6cb9c1d78d0783 104 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 23 95 1.5E-14 T 30-10-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core CL1_0967 112b9e9d7dce7fb8b1ac6212efb40fde 487 Gene3D G3DSA:3.50.50.60 1 96 1.1E-19 T 30-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily CL1_0967 112b9e9d7dce7fb8b1ac6212efb40fde 487 Gene3D G3DSA:3.50.50.60 127 236 2.3E-5 T 30-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily CL1_0967 112b9e9d7dce7fb8b1ac6212efb40fde 487 Pfam PF01946 Thi4 family 11 41 1.7E-7 T 30-10-2018 CL1_0967 112b9e9d7dce7fb8b1ac6212efb40fde 487 SUPERFAMILY SSF51905 11 463 5.2E-32 T 30-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily CL1_0967 112b9e9d7dce7fb8b1ac6212efb40fde 487 PIRSF PIRSF038984 1 90 5.2E-10 T 30-10-2018 IPR028348 FAD dependent protein CL1_0967 112b9e9d7dce7fb8b1ac6212efb40fde 487 PIRSF PIRSF038984 134 467 3.5E-26 T 30-10-2018 IPR028348 FAD dependent protein CL1_0967 112b9e9d7dce7fb8b1ac6212efb40fde 487 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 13 32 1.6E-11 T 30-10-2018 CL1_0967 112b9e9d7dce7fb8b1ac6212efb40fde 487 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 419 441 1.6E-11 T 30-10-2018 CL1_0967 112b9e9d7dce7fb8b1ac6212efb40fde 487 Gene3D G3DSA:3.50.50.60 420 460 3.1E-7 T 30-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily CL1_0967 112b9e9d7dce7fb8b1ac6212efb40fde 487 Pfam PF01134 Glucose inhibited division protein A 385 461 5.0E-4 T 30-10-2018 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 CL1_0399 a459019c428b15f4190dc49a0ec38add 152 SUPERFAMILY SSF50104 55 147 1.81E-17 T 30-10-2018 IPR008991 Translation protein SH3-like domain superfamily CL1_0399 a459019c428b15f4190dc49a0ec38add 152 Gene3D G3DSA:3.30.70.940 2 87 1.1E-33 T 30-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 CL1_0399 a459019c428b15f4190dc49a0ec38add 152 Pfam PF00467 KOW motif 95 126 4.6E-9 T 30-10-2018 IPR005824 KOW CL1_0399 a459019c428b15f4190dc49a0ec38add 152 Gene3D G3DSA:2.30.30.30 88 152 2.1E-28 T 30-10-2018 IPR014722 Ribosomal protein L2, domain 2 CL1_0399 a459019c428b15f4190dc49a0ec38add 152 Hamap MF_00950 Transcription elongation factor Spt5 [spt5]. 5 148 38.055 T 30-10-2018 IPR011590 Transcription elongation factor Spt5, archaeal GO:0003746 CL1_0399 a459019c428b15f4190dc49a0ec38add 152 SMART SM00739 92 119 3.5E-7 T 30-10-2018 IPR005824 KOW CL1_0399 a459019c428b15f4190dc49a0ec38add 152 TIGRFAM TIGR00405 KOW_elon_Spt5: transcription elongation factor Spt5 7 150 3.8E-52 T 30-10-2018 IPR011590 Transcription elongation factor Spt5, archaeal GO:0003746 CL1_0399 a459019c428b15f4190dc49a0ec38add 152 Pfam PF03439 Early transcription elongation factor of RNA pol II, NGN section 5 84 5.7E-23 T 30-10-2018 IPR005100 NGN domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 CL1_0399 a459019c428b15f4190dc49a0ec38add 152 SMART SM00738 3 87 1.0E-19 T 30-10-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 CL1_0608 ccc1611c0b95b5c30d16fdfdb1875424 201 Hamap MF_01337_A 50S ribosomal protein L18 [rplR]. 5 192 44.845 T 30-10-2018 IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0008097 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0608 ccc1611c0b95b5c30d16fdfdb1875424 201 Pfam PF17144 Ribosomal large subunit proteins 60S L5, and 50S L18 6 94 1.1E-14 T 30-10-2018 IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0008097 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0608 ccc1611c0b95b5c30d16fdfdb1875424 201 Pfam PF17144 Ribosomal large subunit proteins 60S L5, and 50S L18 98 134 8.2E-9 T 30-10-2018 IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0008097 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0608 ccc1611c0b95b5c30d16fdfdb1875424 201 SUPERFAMILY SSF53137 2 195 1.05E-62 T 30-10-2018 CL1_0608 ccc1611c0b95b5c30d16fdfdb1875424 201 PRINTS PR00058 Ribosomal protein L5 signature 123 142 6.7E-10 T 30-10-2018 IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0008097 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0608 ccc1611c0b95b5c30d16fdfdb1875424 201 PRINTS PR00058 Ribosomal protein L5 signature 1 12 6.7E-10 T 30-10-2018 IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0008097 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0608 ccc1611c0b95b5c30d16fdfdb1875424 201 PRINTS PR00058 Ribosomal protein L5 signature 103 122 6.7E-10 T 30-10-2018 IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0008097 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0608 ccc1611c0b95b5c30d16fdfdb1875424 201 Pfam PF14204 Ribosomal L18 C-terminal region 143 194 4.0E-12 T 30-10-2018 IPR025607 Ribosomal protein L5 eukaryotic/L18 archaeal, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0608 ccc1611c0b95b5c30d16fdfdb1875424 201 Gene3D G3DSA:3.30.420.100 1 197 4.8E-72 T 30-10-2018 CL1_1624 9e4d8c8833ea257c95b9019747b57c38 145 SMART SM00465 18 113 1.6E-7 T 30-10-2018 IPR000305 GIY-YIG endonuclease CL1_1624 9e4d8c8833ea257c95b9019747b57c38 145 Pfam PF01986 Domain of unknown function DUF123 25 110 1.1E-20 T 30-10-2018 IPR002837 Protein of unknown function DUF123 CL1_1446 8b601e3a59a8c78cc363aad31938a2b0 648 SUPERFAMILY SSF53850 155 636 1.15E-84 T 30-10-2018 CL1_1446 8b601e3a59a8c78cc363aad31938a2b0 648 Gene3D G3DSA:3.90.76.10 166 357 5.1E-23 T 30-10-2018 CL1_1446 8b601e3a59a8c78cc363aad31938a2b0 648 PIRSF PIRSF002741 32 142 3.5E-5 T 30-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CL1_1446 8b601e3a59a8c78cc363aad31938a2b0 648 PIRSF PIRSF002741 149 355 7.9E-9 T 30-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CL1_1446 8b601e3a59a8c78cc363aad31938a2b0 648 PIRSF PIRSF002741 371 644 1.4E-53 T 30-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CL1_1446 8b601e3a59a8c78cc363aad31938a2b0 648 SUPERFAMILY SSF53850 59 137 3.44E-7 T 30-10-2018 CL1_1446 8b601e3a59a8c78cc363aad31938a2b0 648 ProSitePatterns PS00018 EF-hand calcium-binding domain. 268 280 - T 30-10-2018 IPR018247 EF-Hand 1, calcium-binding site CL1_1446 8b601e3a59a8c78cc363aad31938a2b0 648 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 202 637 2.9E-66 T 30-10-2018 IPR000914 Solute-binding protein family 5 domain CL1_1446 8b601e3a59a8c78cc363aad31938a2b0 648 Gene3D G3DSA:3.40.190.10 375 481 1.8E-19 T 30-10-2018 CL1_1446 8b601e3a59a8c78cc363aad31938a2b0 648 Gene3D G3DSA:3.10.105.10 482 643 6.4E-43 T 30-10-2018 CL1_0865 0a47eb32da962e8638544149b3b5896c 184 Gene3D G3DSA:3.90.1140.10 1 184 2.6E-67 T 30-10-2018 CL1_0865 0a47eb32da962e8638544149b3b5896c 184 TIGRFAM TIGR02258 2_5_ligase: 2'-5' RNA ligase 1 182 1.8E-54 T 30-10-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 CL1_0865 0a47eb32da962e8638544149b3b5896c 184 SUPERFAMILY SSF55144 1 182 1.74E-45 T 30-10-2018 IPR009097 Cyclic phosphodiesterase CL1_0865 0a47eb32da962e8638544149b3b5896c 184 Hamap MF_01940 RNA 2',3'-cyclic phosphodiesterase [thpR]. 1 182 27.185 T 30-10-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 CL1_0865 0a47eb32da962e8638544149b3b5896c 184 Pfam PF02834 LigT like Phosphoesterase 98 174 4.1E-13 T 30-10-2018 IPR014051 Phosphoesterase, HXTX CL1_0865 0a47eb32da962e8638544149b3b5896c 184 Pfam PF02834 LigT like Phosphoesterase 7 91 5.1E-20 T 30-10-2018 IPR014051 Phosphoesterase, HXTX CL1_0952 722dfa687f0460c511d01b43e5be5521 258 Gene3D G3DSA:3.30.70.1450 136 233 1.6E-14 T 30-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 CL1_0952 722dfa687f0460c511d01b43e5be5521 258 Pfam PF02080 TrkA-C domain 159 227 2.5E-11 T 30-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CL1_0952 722dfa687f0460c511d01b43e5be5521 258 SUPERFAMILY SSF116726 147 229 3.4E-13 T 30-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 CL1_1538 c03d89528420b57a2f897f9fcdff386e 259 SUPERFAMILY SSF101852 163 254 2.48E-24 T 30-10-2018 IPR023227 S-adenosyl-l-methionine hydroxide adenosyltransferase, C-terminal CL1_1538 c03d89528420b57a2f897f9fcdff386e 259 Gene3D G3DSA:3.40.50.10790 1 160 8.9E-60 T 30-10-2018 IPR023228 S-adenosyl-l-methionine hydroxide adenosyltransferase, N-terminal CL1_1538 c03d89528420b57a2f897f9fcdff386e 259 Gene3D G3DSA:2.40.30.90 161 256 2.3E-34 T 30-10-2018 IPR023227 S-adenosyl-l-methionine hydroxide adenosyltransferase, C-terminal CL1_1538 c03d89528420b57a2f897f9fcdff386e 259 SUPERFAMILY SSF102522 1 161 1.03E-54 T 30-10-2018 IPR023228 S-adenosyl-l-methionine hydroxide adenosyltransferase, N-terminal CL1_1538 c03d89528420b57a2f897f9fcdff386e 259 PIRSF PIRSF006779 1 256 1.0E-74 T 30-10-2018 IPR002747 SAM-dependent chlorinase/fluorinase CL1_1538 c03d89528420b57a2f897f9fcdff386e 259 Pfam PF01887 S-adenosyl-l-methionine hydroxide adenosyltransferase 2 252 1.5E-75 T 30-10-2018 IPR002747 SAM-dependent chlorinase/fluorinase CL1_0502 665ea094607ec3e1828713d15353f72a 99 Pfam PF04242 Protein of unknown function (DUF424) 7 97 2.1E-32 T 30-10-2018 IPR007355 Protein of unknown function DUF424 CL1_0502 665ea094607ec3e1828713d15353f72a 99 Gene3D G3DSA:3.30.1860.10 1 97 7.4E-34 T 30-10-2018 CL1_0884 268c1ac997e97dfd05d12ba3969eb13b 644 SUPERFAMILY SSF81296 24 84 5.32E-11 T 30-10-2018 IPR014756 Immunoglobulin E-set CL1_0884 268c1ac997e97dfd05d12ba3969eb13b 644 Gene3D G3DSA:2.60.40.10 1 103 7.4E-20 T 30-10-2018 IPR013783 Immunoglobulin-like fold CL1_0884 268c1ac997e97dfd05d12ba3969eb13b 644 Pfam PF16561 Glycogen recognition site of AMP-activated protein kinase 20 83 1.3E-7 T 30-10-2018 IPR032640 AMP-activated protein kinase, glycogen-binding domain Reactome: R-HSA-1445148|Reactome: R-HSA-1632852|Reactome: R-HSA-2151209|Reactome: R-HSA-380972|Reactome: R-HSA-5628897|Reactome: R-HSA-6804756 CL1_0884 268c1ac997e97dfd05d12ba3969eb13b 644 SUPERFAMILY SSF51445 194 585 2.19E-94 T 30-10-2018 IPR017853 Glycoside hydrolase superfamily CL1_0884 268c1ac997e97dfd05d12ba3969eb13b 644 Pfam PF02903 Alpha amylase, N-terminal ig-like domain 109 190 3.7E-7 T 30-10-2018 IPR004185 Glycoside hydrolase, family 13, N-terminal Ig-like domain GO:0004553|GO:0005975 CL1_0884 268c1ac997e97dfd05d12ba3969eb13b 644 SMART SM00642 209 577 1.2E-92 T 30-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CL1_0884 268c1ac997e97dfd05d12ba3969eb13b 644 Pfam PF00128 Alpha amylase, catalytic domain 236 543 4.8E-59 T 30-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CL1_0884 268c1ac997e97dfd05d12ba3969eb13b 644 Gene3D G3DSA:2.60.40.10 104 196 1.6E-21 T 30-10-2018 IPR013783 Immunoglobulin-like fold CL1_0884 268c1ac997e97dfd05d12ba3969eb13b 644 Gene3D G3DSA:3.20.20.80 197 583 1.1E-142 T 30-10-2018 CL1_0884 268c1ac997e97dfd05d12ba3969eb13b 644 SUPERFAMILY SSF81296 108 202 3.64E-10 T 30-10-2018 IPR014756 Immunoglobulin E-set CL1_0857 60aa50711aa0c72e1f0989f545450753 372 Gene3D G3DSA:3.90.550.10 1 225 3.2E-57 T 30-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases CL1_0857 60aa50711aa0c72e1f0989f545450753 372 Pfam PF00535 Glycosyl transferase family 2 6 167 1.7E-27 T 30-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CL1_0857 60aa50711aa0c72e1f0989f545450753 372 SUPERFAMILY SSF53448 2 252 8.68E-45 T 30-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases CL1_0481 afe6d8a0dff34318a5b63bd20d3ddaa8 139 Gene3D G3DSA:3.30.2320.50 2 130 1.4E-27 T 30-10-2018 CL1_0481 afe6d8a0dff34318a5b63bd20d3ddaa8 139 Pfam PF01155 Hydrogenase/urease nickel incorporation, metallochaperone, hypA 1 132 7.4E-28 T 30-10-2018 IPR000688 Hydrogenase maturation factor HypA/HybF GO:0016151|GO:0051604 CL1_0481 afe6d8a0dff34318a5b63bd20d3ddaa8 139 Gene3D G3DSA:2.20.28.10 69 123 1.4E-27 T 30-10-2018 CL1_0481 afe6d8a0dff34318a5b63bd20d3ddaa8 139 PIRSF PIRSF004761 1 137 5.3E-35 T 30-10-2018 IPR000688 Hydrogenase maturation factor HypA/HybF GO:0016151|GO:0051604 CL1_0481 afe6d8a0dff34318a5b63bd20d3ddaa8 139 ProSitePatterns PS01249 Hydrogenases expression/synthesis hypA family signature. 34 76 - T 30-10-2018 IPR020538 Hydrogenase nickel incorporation protein HypA/HybF, conserved site CL1_0481 afe6d8a0dff34318a5b63bd20d3ddaa8 139 Hamap MF_00213 Hydrogenase maturation factor HypA [hypA]. 1 134 21.685 T 30-10-2018 IPR000688 Hydrogenase maturation factor HypA/HybF GO:0016151|GO:0051604 CL1_0311 0ea0d82c64c3c637868b8d02ba7144b1 95 Pfam PF13656 RNA polymerase Rpb3/Rpb11 dimerisation domain 13 83 3.4E-20 T 30-10-2018 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 CL1_0311 0ea0d82c64c3c637868b8d02ba7144b1 95 ProSitePatterns PS01154 RNA polymerases L / 13 to 16 Kd subunits signature. 17 48 - T 30-10-2018 IPR008193 DNA-directed RNA polymerase Rpb11, 13-16kDa subunit, conserved site GO:0003677|GO:0003899|GO:0006351 CL1_0311 0ea0d82c64c3c637868b8d02ba7144b1 95 Hamap MF_00261 DNA-directed RNA polymerase subunit L [rpoL]. 1 89 20.13 T 30-10-2018 IPR022905 DNA-directed RNA polymerase subunit L (Rpo11) GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CL1_0311 0ea0d82c64c3c637868b8d02ba7144b1 95 Gene3D G3DSA:3.30.1360.10 1 94 6.4E-34 T 30-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CL1_0311 0ea0d82c64c3c637868b8d02ba7144b1 95 SUPERFAMILY SSF55257 1 93 5.23E-25 T 30-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CL1_0493 305d5a279b23da8ab54d96668b95c020 377 PIRSF PIRSF016907 1 377 6.2E-148 T 30-10-2018 IPR011386 Putative ATP-NAD kinase CL1_0493 305d5a279b23da8ab54d96668b95c020 377 Pfam PF01513 ATP-NAD kinase 2 375 1.4E-46 T 30-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 CL1_0493 305d5a279b23da8ab54d96668b95c020 377 Gene3D G3DSA:3.40.50.10330 90 202 7.4E-7 T 30-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 CL1_0493 305d5a279b23da8ab54d96668b95c020 377 SUPERFAMILY SSF111331 92 174 2.13E-8 T 30-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily CL1_0745 ace1ccd723df09293d53c7e20cd71f13 216 Gene3D G3DSA:3.60.21.10 11 123 1.1E-10 T 30-10-2018 IPR029052 Metallo-dependent phosphatase-like CL1_0745 ace1ccd723df09293d53c7e20cd71f13 216 SUPERFAMILY SSF56300 20 156 1.16E-14 T 30-10-2018 CL1_0745 ace1ccd723df09293d53c7e20cd71f13 216 PIRSF PIRSF000887 7 214 1.3E-37 T 30-10-2018 IPR024173 Phosphoesterase, MJ0037 CL1_0745 ace1ccd723df09293d53c7e20cd71f13 216 Pfam PF00149 Calcineurin-like phosphoesterase 20 116 9.0E-10 T 30-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CL1_1577 63dbae68be2ab1f0f825e4553c071523 138 Pfam PF01985 CRS1 / YhbY (CRM) domain 5 92 2.3E-12 T 30-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 CL1_1577 63dbae68be2ab1f0f825e4553c071523 138 SUPERFAMILY SSF75471 5 101 5.49E-18 T 30-10-2018 IPR035920 YhbY-like superfamily CL1_1577 63dbae68be2ab1f0f825e4553c071523 138 ProDom PD010559 RNA-BINDING YHBY UPF0044 PREDICTED RNA RIBOSOMAL CONTAINING KH BINDING DOMAIN 11 95 3.0E-36 T 30-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 CL1_1577 63dbae68be2ab1f0f825e4553c071523 138 SMART SM01103 5 92 1.6E-26 T 30-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 CL1_1577 63dbae68be2ab1f0f825e4553c071523 138 Gene3D G3DSA:3.30.110.60 5 116 1.3E-19 T 30-10-2018 IPR035920 YhbY-like superfamily CL1_0104 a25238605b25b85f3b0420a6382e7576 273 Pfam PF06508 Queuosine biosynthesis protein QueC 23 82 2.3E-7 T 30-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 CL1_0104 a25238605b25b85f3b0420a6382e7576 273 Gene3D G3DSA:3.40.50.620 1 259 1.9E-29 T 30-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CL1_0104 a25238605b25b85f3b0420a6382e7576 273 SUPERFAMILY SSF52402 3 183 1.21E-32 T 30-10-2018 CL1_0104 a25238605b25b85f3b0420a6382e7576 273 PIRSF PIRSF036670 1 261 3.5E-127 T 30-10-2018 IPR012122 ATPase, PP-loop, MJ1016-related CL1_0803 6d0a9843f7baca1198b18fbcdc821043 485 SUPERFAMILY SSF54631 94 204 1.77E-33 T 30-10-2018 CL1_0803 6d0a9843f7baca1198b18fbcdc821043 485 Gene3D G3DSA:3.20.20.70 4 484 4.4E-198 T 30-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CL1_0803 6d0a9843f7baca1198b18fbcdc821043 485 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 14 453 6.7E-188 T 30-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 CL1_0803 6d0a9843f7baca1198b18fbcdc821043 485 Pfam PF00571 CBS domain 100 146 1.1E-13 T 30-10-2018 IPR000644 CBS domain CL1_0803 6d0a9843f7baca1198b18fbcdc821043 485 Pfam PF00571 CBS domain 153 205 6.2E-15 T 30-10-2018 IPR000644 CBS domain CL1_0803 6d0a9843f7baca1198b18fbcdc821043 485 SUPERFAMILY SSF51412 10 475 1.83E-111 T 30-10-2018 CL1_0803 6d0a9843f7baca1198b18fbcdc821043 485 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 292 304 - T 30-10-2018 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 CL1_0803 6d0a9843f7baca1198b18fbcdc821043 485 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 14 471 7.4E-148 T 30-10-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 CL1_0803 6d0a9843f7baca1198b18fbcdc821043 485 SMART SM01240 13 471 5.2E-261 T 30-10-2018 CL1_0803 6d0a9843f7baca1198b18fbcdc821043 485 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 14 484 79.908 T 30-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 CL1_0803 6d0a9843f7baca1198b18fbcdc821043 485 SMART SM00116 102 150 2.0E-13 T 30-10-2018 IPR000644 CBS domain CL1_0803 6d0a9843f7baca1198b18fbcdc821043 485 SMART SM00116 160 208 2.4E-11 T 30-10-2018 IPR000644 CBS domain CL1_0803 6d0a9843f7baca1198b18fbcdc821043 485 PIRSF PIRSF000130 3 485 6.7E-194 T 30-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 CL1_0940 8d3cc0876b585a734b4c2383d6f5ff00 142 Gene3D G3DSA:3.30.160.750 66 129 4.4E-25 T 30-10-2018 CL1_0940 8d3cc0876b585a734b4c2383d6f5ff00 142 TIGRFAM TIGR03330 SAM_DCase_Bsu: S-adenosylmethionine decarboxylase proenzyme 6 116 8.2E-46 T 30-10-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 CL1_0940 8d3cc0876b585a734b4c2383d6f5ff00 142 SUPERFAMILY SSF56276 6 120 3.34E-43 T 30-10-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 CL1_0940 8d3cc0876b585a734b4c2383d6f5ff00 142 Hamap MF_00464 S-adenosylmethionine decarboxylase proenzyme [speH]. 4 120 31.789 T 30-10-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 CL1_0940 8d3cc0876b585a734b4c2383d6f5ff00 142 Gene3D G3DSA:3.30.360.110 4 65 2.4E-20 T 30-10-2018 CL1_0940 8d3cc0876b585a734b4c2383d6f5ff00 142 Pfam PF02675 S-adenosylmethionine decarboxylase 10 116 1.3E-39 T 30-10-2018 IPR003826 S-adenosylmethionine decarboxylase family, prokaryotic GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 CL1_1475 792b18f4d943228ddb42062537790cdc 432 Pfam PF12804 MobA-like NTP transferase domain 6 114 2.4E-15 T 30-10-2018 IPR025877 MobA-like NTP transferase CL1_1475 792b18f4d943228ddb42062537790cdc 432 SUPERFAMILY SSF53448 5 221 6.05E-33 T 30-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases CL1_1475 792b18f4d943228ddb42062537790cdc 432 Gene3D G3DSA:1.20.120.1760 230 424 5.1E-56 T 30-10-2018 CL1_1475 792b18f4d943228ddb42062537790cdc 432 Gene3D G3DSA:3.90.550.10 3 220 2.5E-54 T 30-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases CL1_1475 792b18f4d943228ddb42062537790cdc 432 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 295 317 - T 30-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CL1_1475 792b18f4d943228ddb42062537790cdc 432 Pfam PF01066 CDP-alcohol phosphatidyltransferase 255 317 3.7E-9 T 30-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CL1_1047 dee2bb4c8e419562b8d55ed86e90738b 257 TIGRFAM TIGR01694 MTAP: methylthioadenosine phosphorylase 4 238 8.6E-101 T 30-10-2018 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112|Reactome: R-HSA-8950505 CL1_1047 dee2bb4c8e419562b8d55ed86e90738b 257 Pfam PF01048 Phosphorylase superfamily 3 237 2.0E-49 T 30-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CL1_1047 dee2bb4c8e419562b8d55ed86e90738b 257 Hamap MF_01963 S-methyl-5'-thioadenosine phosphorylase [mtnP]. 2 257 45.194 T 30-10-2018 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112|Reactome: R-HSA-8950505 CL1_1047 dee2bb4c8e419562b8d55ed86e90738b 257 SUPERFAMILY SSF53167 1 255 3.4E-92 T 30-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 CL1_1047 dee2bb4c8e419562b8d55ed86e90738b 257 ProSitePatterns PS01240 Purine and other phosphorylases family 2 signature. 48 88 - T 30-10-2018 IPR018099 Purine phosphorylase, family 2, conserved site GO:0016763 CL1_1047 dee2bb4c8e419562b8d55ed86e90738b 257 Gene3D G3DSA:3.40.50.1580 1 257 1.5E-102 T 30-10-2018 CL1_1992 8bd119188711ece38614fa3c68eaa113 380 SUPERFAMILY SSF51556 49 342 4.45E-28 T 30-10-2018 IPR032466 Metal-dependent hydrolase CL1_1992 8bd119188711ece38614fa3c68eaa113 380 Pfam PF01979 Amidohydrolase family 244 369 1.7E-10 T 30-10-2018 IPR006680 Amidohydrolase-related GO:0016787 CL1_1992 8bd119188711ece38614fa3c68eaa113 380 Gene3D G3DSA:3.20.20.140 50 338 4.9E-72 T 30-10-2018 CL1_1992 8bd119188711ece38614fa3c68eaa113 380 Gene3D G3DSA:2.30.40.10 44 372 4.9E-72 T 30-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 CL1_1825 44774e606d08d83554c072b50e5dcbbe 195 PIRSF PIRSF000495 1 195 2.4E-56 T 30-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 CL1_1825 44774e606d08d83554c072b50e5dcbbe 195 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 2 193 4.4E-60 T 30-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 CL1_1825 44774e606d08d83554c072b50e5dcbbe 195 Gene3D G3DSA:3.40.50.880 1 194 1.6E-61 T 30-10-2018 IPR029062 Class I glutamine amidotransferase-like CL1_1825 44774e606d08d83554c072b50e5dcbbe 195 Hamap MF_00278 Imidazole glycerol phosphate synthase subunit HisH [hisH]. 1 195 33.658 T 30-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 CL1_1825 44774e606d08d83554c072b50e5dcbbe 195 SUPERFAMILY SSF52317 1 193 8.6E-47 T 30-10-2018 IPR029062 Class I glutamine amidotransferase-like CL1_1825 44774e606d08d83554c072b50e5dcbbe 195 Pfam PF00117 Glutamine amidotransferase class-I 36 187 1.8E-19 T 30-10-2018 IPR017926 Glutamine amidotransferase CL1_1998 4053c6247150dbd6ef8051bb5df7f097 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 169 1.7E-11 T 30-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CL1_1998 4053c6247150dbd6ef8051bb5df7f097 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 105 121 1.7E-11 T 30-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CL1_1998 4053c6247150dbd6ef8051bb5df7f097 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 150 1.7E-11 T 30-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CL1_1998 4053c6247150dbd6ef8051bb5df7f097 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 197 217 1.7E-11 T 30-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CL1_1998 4053c6247150dbd6ef8051bb5df7f097 239 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 55 66 1.7E-11 T 30-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CL1_1998 4053c6247150dbd6ef8051bb5df7f097 239 SUPERFAMILY SSF51735 2 234 1.57E-40 T 30-10-2018 IPR036291 NAD(P)-binding domain superfamily CL1_1998 4053c6247150dbd6ef8051bb5df7f097 239 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 3 233 7.6E-26 T 30-10-2018 CL1_1998 4053c6247150dbd6ef8051bb5df7f097 239 Gene3D G3DSA:3.40.50.720 1 236 3.3E-37 T 30-10-2018 CL1_2024 3f9488c132cd7248006ac5c8dfa140e5 322 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 188 197 - T 30-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 CL1_2024 3f9488c132cd7248006ac5c8dfa140e5 322 SUPERFAMILY SSF53383 15 317 1.81E-54 T 30-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase CL1_2024 3f9488c132cd7248006ac5c8dfa140e5 322 Gene3D G3DSA:3.90.1150.10 20 315 7.6E-68 T 30-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 CL1_2024 3f9488c132cd7248006ac5c8dfa140e5 322 Gene3D G3DSA:3.40.640.10 30 233 7.6E-68 T 30-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 CL1_2024 3f9488c132cd7248006ac5c8dfa140e5 322 Pfam PF00155 Aminotransferase class I and II 28 315 1.1E-33 T 30-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CL1_0079 d114d0c9153755715acfce71cf0ec4cc 416 SUPERFAMILY SSF103473 9 408 5.23E-43 T 30-10-2018 IPR036259 MFS transporter superfamily CL1_0079 d114d0c9153755715acfce71cf0ec4cc 416 PRINTS PR01988 Putative bacilysin exporter bacE signature 166 183 4.1E-6 T 30-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CL1_0079 d114d0c9153755715acfce71cf0ec4cc 416 PRINTS PR01988 Putative bacilysin exporter bacE signature 50 68 4.1E-6 T 30-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CL1_0079 d114d0c9153755715acfce71cf0ec4cc 416 PRINTS PR01988 Putative bacilysin exporter bacE signature 76 94 4.1E-6 T 30-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CL1_0079 d114d0c9153755715acfce71cf0ec4cc 416 PRINTS PR01988 Putative bacilysin exporter bacE signature 139 160 4.1E-6 T 30-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CL1_0079 d114d0c9153755715acfce71cf0ec4cc 416 TIGRFAM TIGR00900 2A0121: H+ Antiporter protein 11 376 2.9E-103 T 30-10-2018 IPR004751 Drug antiporter protein GO:0015307|GO:0015893 CL1_0079 d114d0c9153755715acfce71cf0ec4cc 416 Pfam PF07690 Major Facilitator Superfamily 15 366 4.0E-29 T 30-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CL1_0079 d114d0c9153755715acfce71cf0ec4cc 416 Gene3D G3DSA:1.20.1250.20 6 398 2.3E-36 T 30-10-2018 CL1_0834 8a67061c12cc5219d8ac2850d88242c4 366 Gene3D G3DSA:3.40.50.2000 165 344 2.0E-70 T 30-10-2018 CL1_0834 8a67061c12cc5219d8ac2850d88242c4 366 Pfam PF00534 Glycosyl transferases group 1 179 343 1.2E-36 T 30-10-2018 IPR001296 Glycosyl transferase, family 1 CL1_0834 8a67061c12cc5219d8ac2850d88242c4 366 SUPERFAMILY SSF53756 12 360 5.14E-79 T 30-10-2018 CL1_0834 8a67061c12cc5219d8ac2850d88242c4 366 Pfam PF13439 Glycosyltransferase Family 4 14 167 5.1E-12 T 30-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 CL1_0834 8a67061c12cc5219d8ac2850d88242c4 366 Gene3D G3DSA:3.40.50.2000 24 357 2.0E-70 T 30-10-2018 CL1_1657 e4cfb6a5f5f1812c13bb44276e4d96ce 459 SUPERFAMILY SSF53613 10 455 2.54E-156 T 30-10-2018 IPR029056 Ribokinase-like CL1_1657 e4cfb6a5f5f1812c13bb44276e4d96ce 459 Gene3D G3DSA:3.40.1190.20 12 446 8.4E-161 T 30-10-2018 IPR029056 Ribokinase-like CL1_1657 e4cfb6a5f5f1812c13bb44276e4d96ce 459 Gene3D G3DSA:3.30.1110.20 18 198 8.4E-161 T 30-10-2018 CL1_1657 e4cfb6a5f5f1812c13bb44276e4d96ce 459 Pfam PF04587 ADP-specific Phosphofructokinase/Glucokinase conserved region 11 447 1.0E-109 T 30-10-2018 IPR007666 ADP-specific phosphofructokinase/glucokinase GO:0005975|GO:0016773 Reactome: R-HSA-70171 CL1_1657 e4cfb6a5f5f1812c13bb44276e4d96ce 459 Hamap MF_00561 ADP-specific phosphofructokinase [pfkC]. 4 456 44.526 T 30-10-2018 IPR011790 ADP-specific phosphofructokinase, archaeal GO:0005737|GO:0006000|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.146|KEGG: 00030+2.7.1.146|KEGG: 00680+2.7.1.146|MetaCyc: PWY-6142 CL1_1657 e4cfb6a5f5f1812c13bb44276e4d96ce 459 TIGRFAM TIGR02045 P_fruct_ADP: ADP-specific phosphofructokinase 11 456 5.7E-233 T 30-10-2018 IPR011790 ADP-specific phosphofructokinase, archaeal GO:0005737|GO:0006000|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.146|KEGG: 00030+2.7.1.146|KEGG: 00680+2.7.1.146|MetaCyc: PWY-6142 CL1_1657 e4cfb6a5f5f1812c13bb44276e4d96ce 459 PIRSF PIRSF015883 1 456 5.3E-201 T 30-10-2018 IPR015990 ADP-specific phosphofructokinase/glucokinase, archaeal GO:0000287|GO:0006096|GO:0016773 CL1_1928 cc01f5ccdbfab45ce38d07703436e753 358 Gene3D G3DSA:1.10.3210.10 1 256 4.8E-74 T 30-10-2018 CL1_1928 cc01f5ccdbfab45ce38d07703436e753 358 SMART SM00471 46 156 2.4E-15 T 30-10-2018 IPR003607 HD/PDEase domain CL1_1928 cc01f5ccdbfab45ce38d07703436e753 358 SUPERFAMILY SSF109604 1 352 7.33E-86 T 30-10-2018 CL1_1928 cc01f5ccdbfab45ce38d07703436e753 358 Pfam PF01966 HD domain 50 134 2.5E-11 T 30-10-2018 IPR006674 HD domain CL1_1743 b74d4b7f44cfbac233283038b9b1c339 67 SUPERFAMILY SSF57716 6 56 5.84E-21 T 30-10-2018 CL1_1743 b74d4b7f44cfbac233283038b9b1c339 67 ProSitePatterns PS01073 Ribosomal protein L24e signature. 9 26 - T 30-10-2018 IPR023442 Ribosomal protein L24e, conserved site CL1_1743 b74d4b7f44cfbac233283038b9b1c339 67 Hamap MF_00773 50S ribosomal protein L24e [rpl24e]. 2 55 27.527 T 30-10-2018 IPR023438 Ribosomal protein L24e GO:0003735|GO:0005622|GO:0005840|GO:0006412 CL1_1743 b74d4b7f44cfbac233283038b9b1c339 67 SMART SM00746 7 45 3.4E-12 T 30-10-2018 IPR011017 TRASH domain CL1_1743 b74d4b7f44cfbac233283038b9b1c339 67 Gene3D G3DSA:2.30.170.20 2 66 2.1E-27 T 30-10-2018 IPR038630 Ribosomal protein L24e/L24 superfamily CL1_1743 b74d4b7f44cfbac233283038b9b1c339 67 Pfam PF01246 Ribosomal protein L24e 3 60 3.0E-25 T 30-10-2018 IPR000988 Ribosomal protein L24e-related CL1_1397 a1b88b438708adfb0cf6ba210bc99f7e 418 Pfam PF00155 Aminotransferase class I and II 45 405 2.1E-40 T 30-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CL1_1397 a1b88b438708adfb0cf6ba210bc99f7e 418 Gene3D G3DSA:3.90.1150.10 34 409 8.8E-163 T 30-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 CL1_1397 a1b88b438708adfb0cf6ba210bc99f7e 418 Gene3D G3DSA:3.40.640.10 79 304 8.8E-163 T 30-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 CL1_1397 a1b88b438708adfb0cf6ba210bc99f7e 418 SUPERFAMILY SSF53383 15 411 8.43E-121 T 30-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase CL1_1690 26826679975f4316c3cad28e61cf1101 157 Gene3D G3DSA:3.30.70.920 56 148 2.2E-12 T 30-10-2018 CL1_1690 26826679975f4316c3cad28e61cf1101 157 SUPERFAMILY SSF54909 66 148 4.83E-7 T 30-10-2018 IPR011008 Dimeric alpha-beta barrel CL1_1690 26826679975f4316c3cad28e61cf1101 157 SUPERFAMILY SSF46785 4 62 9.22E-16 T 30-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CL1_1690 26826679975f4316c3cad28e61cf1101 157 Pfam PF13412 Winged helix-turn-helix DNA-binding 5 51 4.3E-15 T 30-10-2018 CL1_1690 26826679975f4316c3cad28e61cf1101 157 Gene3D G3DSA:1.10.10.10 2 55 1.2E-19 T 30-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CL1_1690 26826679975f4316c3cad28e61cf1101 157 SMART SM00344 4 112 5.7E-35 T 30-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CL1_1690 26826679975f4316c3cad28e61cf1101 157 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 31 50 1.4E-16 T 30-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 CL1_1690 26826679975f4316c3cad28e61cf1101 157 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 4 20 1.4E-16 T 30-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 CL1_1690 26826679975f4316c3cad28e61cf1101 157 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 20 31 1.4E-16 T 30-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 CL1_1690 26826679975f4316c3cad28e61cf1101 157 Pfam PF01037 Lrp/AsnC ligand binding domain 79 125 4.7E-7 T 30-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CL1_1690 26826679975f4316c3cad28e61cf1101 157 ProSitePatterns PS00519 AsnC-type HTH domain signature. 22 48 - T 30-10-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site CL1_1510 dc91f0fd93f3073ea646baa91548bf3d 466 Pfam PF03008 Archaea bacterial proteins of unknown function 308 406 2.0E-32 T 30-10-2018 IPR004256 Domain of unknown function DUF234, DEXX-box ATPase C-terminal CL1_1510 dc91f0fd93f3073ea646baa91548bf3d 466 Gene3D G3DSA:3.40.50.300 1 169 1.1E-24 T 30-10-2018 CL1_1510 dc91f0fd93f3073ea646baa91548bf3d 466 SUPERFAMILY SSF46785 240 318 2.27E-6 T 30-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CL1_1510 dc91f0fd93f3073ea646baa91548bf3d 466 Pfam PF01637 ATPase domain predominantly from Archaea 6 203 5.9E-18 T 30-10-2018 IPR011579 ATPase domain GO:0005524 CL1_1510 dc91f0fd93f3073ea646baa91548bf3d 466 SUPERFAMILY SSF52540 4 242 3.55E-34 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_1522 c8b53077a9b08a6b9f14a57dce02b24e 421 ProSitePatterns PS00738 S-adenosyl-L-homocysteine hydrolase signature 1. 78 92 - T 30-10-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CL1_1522 c8b53077a9b08a6b9f14a57dce02b24e 421 PIRSF PIRSF001109 1 421 4.9E-199 T 30-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CL1_1522 c8b53077a9b08a6b9f14a57dce02b24e 421 SMART SM00996 6 420 8.0E-143 T 30-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CL1_1522 c8b53077a9b08a6b9f14a57dce02b24e 421 TIGRFAM TIGR00936 ahcY: adenosylhomocysteinase 7 421 2.3E-212 T 30-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CL1_1522 c8b53077a9b08a6b9f14a57dce02b24e 421 Hamap MF_00563 Adenosylhomocysteinase [ahcY]. 2 421 51.07 T 30-10-2018 IPR034373 Adenosylhomocysteinase GO:0004013|GO:0019510|GO:0051287 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-2408508|Reactome: R-HSA-5578997 CL1_1522 c8b53077a9b08a6b9f14a57dce02b24e 421 ProSitePatterns PS00739 S-adenosyl-L-homocysteine hydrolase signature 2. 210 226 - T 30-10-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CL1_1522 c8b53077a9b08a6b9f14a57dce02b24e 421 Pfam PF00670 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 188 348 1.3E-50 T 30-10-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CL1_1522 c8b53077a9b08a6b9f14a57dce02b24e 421 SUPERFAMILY SSF52283 5 421 5.1E-103 T 30-10-2018 CL1_1522 c8b53077a9b08a6b9f14a57dce02b24e 421 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 6 138 2.6E-35 T 30-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CL1_1522 c8b53077a9b08a6b9f14a57dce02b24e 421 Gene3D G3DSA:3.40.50.1480 9 410 3.1E-177 T 30-10-2018 CL1_1522 c8b53077a9b08a6b9f14a57dce02b24e 421 SMART SM00997 188 349 5.4E-111 T 30-10-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CL1_1522 c8b53077a9b08a6b9f14a57dce02b24e 421 Gene3D G3DSA:3.40.50.720 190 349 3.1E-177 T 30-10-2018 CL1_1522 c8b53077a9b08a6b9f14a57dce02b24e 421 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 143 416 2.7E-28 T 30-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CL1_1522 c8b53077a9b08a6b9f14a57dce02b24e 421 SUPERFAMILY SSF51735 188 350 1.6E-68 T 30-10-2018 IPR036291 NAD(P)-binding domain superfamily CL1_0714 6d5e3dc6737032322073fe48c3f700e7 357 Gene3D G3DSA:2.40.50.140 170 318 1.5E-10 T 30-10-2018 CL1_0714 6d5e3dc6737032322073fe48c3f700e7 357 Pfam PF01336 OB-fold nucleic acid binding domain 73 151 5.4E-12 T 30-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 CL1_0714 6d5e3dc6737032322073fe48c3f700e7 357 SUPERFAMILY SSF50249 181 347 1.67E-15 T 30-10-2018 IPR012340 Nucleic acid-binding, OB-fold CL1_0714 6d5e3dc6737032322073fe48c3f700e7 357 Gene3D G3DSA:2.40.50.140 58 159 3.8E-21 T 30-10-2018 CL1_0714 6d5e3dc6737032322073fe48c3f700e7 357 SUPERFAMILY SSF50249 56 176 2.09E-25 T 30-10-2018 IPR012340 Nucleic acid-binding, OB-fold CL1_0714 6d5e3dc6737032322073fe48c3f700e7 357 Pfam PF08646 Replication factor-A C terminal domain 193 278 5.7E-9 T 30-10-2018 IPR013955 Replication factor A, C-terminal CL1_0726 03de2b070ba7ef0211e1f9a2c78081b2 138 Pfam PF04900 Fcf1 33 130 8.9E-8 T 30-10-2018 IPR006984 rRNA-processing protein Fcf1/Utp23 GO:0032040 CL1_0726 03de2b070ba7ef0211e1f9a2c78081b2 138 SMART SM00670 7 113 7.7E-10 T 30-10-2018 IPR002716 PIN domain CL1_0726 03de2b070ba7ef0211e1f9a2c78081b2 138 SUPERFAMILY SSF88723 7 130 7.46E-25 T 30-10-2018 IPR029060 PIN-like domain superfamily CL1_0726 03de2b070ba7ef0211e1f9a2c78081b2 138 Gene3D G3DSA:3.40.50.1010 7 136 3.6E-29 T 30-10-2018 CL1_0783 878a495a3eeaab1ae31904f27106a528 80 TIGRFAM TIGR00302 TIGR00302: phosphoribosylformylglycinamidine synthase, purS protein 4 77 5.8E-26 T 30-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CL1_0783 878a495a3eeaab1ae31904f27106a528 80 Pfam PF02700 Phosphoribosylformylglycinamidine (FGAM) synthase 4 76 4.9E-26 T 30-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CL1_0783 878a495a3eeaab1ae31904f27106a528 80 Hamap MF_01926 Phosphoribosylformylglycinamidine synthase subunit PurS [purS]. 3 76 20.201 T 30-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CL1_0783 878a495a3eeaab1ae31904f27106a528 80 SUPERFAMILY SSF82697 3 78 1.74E-24 T 30-10-2018 IPR036604 Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CL1_0783 878a495a3eeaab1ae31904f27106a528 80 ProDom PD010362 PHOSPHORIBOSYLFORMYLGLYCINAMIDINE PURS SYNTHETASE SYNTHASE COMPONENT SYNTHASE LIGASE FGAM UPF0062 I 10 77 3.0E-26 T 30-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CL1_0783 878a495a3eeaab1ae31904f27106a528 80 Gene3D G3DSA:3.30.1280.10 1 80 9.1E-29 T 30-10-2018 IPR036604 Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CL1_0541 828f4dd7698329622b6b9af5ef8c0257 112 Gene3D G3DSA:1.10.287.70 8 111 1.4E-14 T 30-10-2018 CL1_0541 828f4dd7698329622b6b9af5ef8c0257 112 Pfam PF07885 Ion channel 32 101 2.7E-11 T 30-10-2018 IPR013099 Potassium channel domain CL1_0541 828f4dd7698329622b6b9af5ef8c0257 112 SUPERFAMILY SSF81324 10 108 4.45E-17 T 30-10-2018 CL1_0446 a1663139bb3ef64f6ef9b2b6b05e4165 215 PIRSF PIRSF002122 1 215 7.2E-48 T 30-10-2018 IPR000235 Ribosomal protein S5/S7 GO:0006412 CL1_0446 a1663139bb3ef64f6ef9b2b6b05e4165 215 Pfam PF00177 Ribosomal protein S7p/S5e 58 215 5.1E-38 T 30-10-2018 IPR023798 Ribosomal protein S7 domain CL1_0446 a1663139bb3ef64f6ef9b2b6b05e4165 215 SUPERFAMILY SSF47973 16 215 4.97E-62 T 30-10-2018 IPR036823 Ribosomal protein S7 domain superfamily CL1_0446 a1663139bb3ef64f6ef9b2b6b05e4165 215 TIGRFAM TIGR01028 uS7_euk_arch: ribosomal protein uS7 14 215 1.3E-89 T 30-10-2018 IPR005716 Ribosomal protein S5/S7, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0446 a1663139bb3ef64f6ef9b2b6b05e4165 215 Hamap MF_00480_A 30S ribosomal protein S7 [rpsG]. 15 215 38.226 T 30-10-2018 IPR026018 Ribosomal protein S7, archaeal CL1_0446 a1663139bb3ef64f6ef9b2b6b05e4165 215 Gene3D G3DSA:1.10.455.10 15 215 1.3E-79 T 30-10-2018 IPR036823 Ribosomal protein S7 domain superfamily CL1_0885 4c28844fb0d6fac4b719434e31ca905b 440 Gene3D G3DSA:3.40.190.10 69 395 9.0E-139 T 30-10-2018 CL1_0885 4c28844fb0d6fac4b719434e31ca905b 440 PRINTS PR00181 Maltose binding protein signature 189 208 4.8E-14 T 30-10-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0008643|GO:0015144 CL1_0885 4c28844fb0d6fac4b719434e31ca905b 440 PRINTS PR00181 Maltose binding protein signature 168 187 4.8E-14 T 30-10-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0008643|GO:0015144 CL1_0885 4c28844fb0d6fac4b719434e31ca905b 440 PRINTS PR00181 Maltose binding protein signature 266 285 4.8E-14 T 30-10-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0008643|GO:0015144 CL1_0885 4c28844fb0d6fac4b719434e31ca905b 440 PRINTS PR00181 Maltose binding protein signature 395 414 4.8E-14 T 30-10-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0008643|GO:0015144 CL1_0885 4c28844fb0d6fac4b719434e31ca905b 440 PRINTS PR00181 Maltose binding protein signature 106 124 4.8E-14 T 30-10-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0008643|GO:0015144 CL1_0885 4c28844fb0d6fac4b719434e31ca905b 440 SUPERFAMILY SSF53850 63 434 8.51E-93 T 30-10-2018 CL1_0885 4c28844fb0d6fac4b719434e31ca905b 440 Pfam PF13416 Bacterial extracellular solute-binding protein 84 379 3.4E-54 T 30-10-2018 IPR006059 Bacterial extracellular solute-binding protein CL1_0885 4c28844fb0d6fac4b719434e31ca905b 440 Gene3D G3DSA:3.40.190.10 176 410 9.0E-139 T 30-10-2018 CL1_0885 4c28844fb0d6fac4b719434e31ca905b 440 ProSitePatterns PS01037 Bacterial extracellular solute-binding proteins, family 1 signature. 171 188 - T 30-10-2018 IPR006061 Solute-binding family 1, conserved site GO:0055085 CL1_0137 619c638ce91f7b954d38021b63fc8a77 625 SUPERFAMILY SSF53807 69 334 1.22E-70 T 30-10-2018 CL1_0137 619c638ce91f7b954d38021b63fc8a77 625 SUPERFAMILY SSF53807 345 609 6.67E-70 T 30-10-2018 CL1_0137 619c638ce91f7b954d38021b63fc8a77 625 Gene3D G3DSA:3.40.50.1980 479 605 2.5E-34 T 30-10-2018 CL1_0137 619c638ce91f7b954d38021b63fc8a77 625 Gene3D G3DSA:3.40.50.1980 207 333 1.1E-35 T 30-10-2018 CL1_0137 619c638ce91f7b954d38021b63fc8a77 625 Pfam PF01497 Periplasmic binding protein 90 308 8.0E-35 T 30-10-2018 IPR002491 ABC transporter periplasmic binding domain CL1_0137 619c638ce91f7b954d38021b63fc8a77 625 Pfam PF01497 Periplasmic binding protein 361 580 3.5E-32 T 30-10-2018 IPR002491 ABC transporter periplasmic binding domain CL1_0137 619c638ce91f7b954d38021b63fc8a77 625 Gene3D G3DSA:3.40.50.1980 343 473 9.4E-35 T 30-10-2018 CL1_0137 619c638ce91f7b954d38021b63fc8a77 625 Gene3D G3DSA:3.40.50.1980 72 201 2.5E-34 T 30-10-2018 CL1_0272 1ca6d072953187c4485894fae9ab148f 407 Pfam PF00534 Glycosyl transferases group 1 195 365 2.6E-24 T 30-10-2018 IPR001296 Glycosyl transferase, family 1 CL1_0272 1ca6d072953187c4485894fae9ab148f 407 Gene3D G3DSA:3.40.50.2000 183 372 4.3E-75 T 30-10-2018 CL1_0272 1ca6d072953187c4485894fae9ab148f 407 Pfam PF13439 Glycosyltransferase Family 4 17 185 3.4E-29 T 30-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 CL1_0272 1ca6d072953187c4485894fae9ab148f 407 Gene3D G3DSA:3.40.50.2000 8 373 4.3E-75 T 30-10-2018 CL1_0272 1ca6d072953187c4485894fae9ab148f 407 SUPERFAMILY SSF53756 5 384 4.22E-78 T 30-10-2018 CL1_1698 a563134498982e84cd9fc8aa15899851 343 SUPERFAMILY SSF52317 37 230 3.89E-10 T 30-10-2018 IPR029062 Class I glutamine amidotransferase-like CL1_0047 d002bfd1b1ae3f154cf618aad3e30626 234 Gene3D G3DSA:3.40.50.300 1 230 5.8E-58 T 30-10-2018 CL1_0047 d002bfd1b1ae3f154cf618aad3e30626 234 PRINTS PR01874 DNA repair protein radA signature 15 43 9.4E-9 T 30-10-2018 CL1_0047 d002bfd1b1ae3f154cf618aad3e30626 234 PRINTS PR01874 DNA repair protein radA signature 57 74 9.4E-9 T 30-10-2018 CL1_0047 d002bfd1b1ae3f154cf618aad3e30626 234 Pfam PF06745 KaiC 6 228 4.4E-53 T 30-10-2018 IPR014774 KaiC-like domain CL1_0047 d002bfd1b1ae3f154cf618aad3e30626 234 SUPERFAMILY SSF52540 3 227 5.27E-41 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_0542 8cea07b123c2a55675aa2b7824d4c43f 419 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 173 195 7.1E-30 T 30-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CL1_0542 8cea07b123c2a55675aa2b7824d4c43f 419 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 343 354 7.1E-30 T 30-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CL1_0542 8cea07b123c2a55675aa2b7824d4c43f 419 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 91 105 7.1E-30 T 30-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CL1_0542 8cea07b123c2a55675aa2b7824d4c43f 419 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 215 235 7.1E-30 T 30-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CL1_0542 8cea07b123c2a55675aa2b7824d4c43f 419 Gene3D G3DSA:3.40.50.720 182 418 8.5E-96 T 30-10-2018 CL1_0542 8cea07b123c2a55675aa2b7824d4c43f 419 SUPERFAMILY SSF53223 4 184 7.36E-66 T 30-10-2018 CL1_0542 8cea07b123c2a55675aa2b7824d4c43f 419 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 99 112 - T 30-10-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CL1_0542 8cea07b123c2a55675aa2b7824d4c43f 419 Gene3D G3DSA:3.40.50.10860 36 180 1.2E-65 T 30-10-2018 CL1_0542 8cea07b123c2a55675aa2b7824d4c43f 419 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 34 161 5.4E-53 T 30-10-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CL1_0542 8cea07b123c2a55675aa2b7824d4c43f 419 SMART SM00839 184 415 5.5E-98 T 30-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CL1_0542 8cea07b123c2a55675aa2b7824d4c43f 419 SUPERFAMILY SSF51735 182 417 4.79E-82 T 30-10-2018 IPR036291 NAD(P)-binding domain superfamily CL1_0542 8cea07b123c2a55675aa2b7824d4c43f 419 PIRSF PIRSF000185 1 418 4.0E-172 T 30-10-2018 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 CL1_0542 8cea07b123c2a55675aa2b7824d4c43f 419 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 182 415 1.6E-75 T 30-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CL1_1379 f90fcaabf544e0c5b7730006ce5cb954 353 SUPERFAMILY SSF55060 180 348 9.71E-43 T 30-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily CL1_1379 f90fcaabf544e0c5b7730006ce5cb954 353 PRINTS PR00959 Mevalonate kinase family signature 6 30 3.4E-39 T 30-10-2018 CL1_1379 f90fcaabf544e0c5b7730006ce5cb954 353 PRINTS PR00959 Mevalonate kinase family signature 94 116 3.4E-39 T 30-10-2018 CL1_1379 f90fcaabf544e0c5b7730006ce5cb954 353 PRINTS PR00959 Mevalonate kinase family signature 137 156 3.4E-39 T 30-10-2018 CL1_1379 f90fcaabf544e0c5b7730006ce5cb954 353 PRINTS PR00959 Mevalonate kinase family signature 297 314 3.4E-39 T 30-10-2018 CL1_1379 f90fcaabf544e0c5b7730006ce5cb954 353 Pfam PF00288 GHMP kinases N terminal domain 94 156 8.0E-15 T 30-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 CL1_1379 f90fcaabf544e0c5b7730006ce5cb954 353 SUPERFAMILY SSF54211 2 177 4.17E-48 T 30-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CL1_1379 f90fcaabf544e0c5b7730006ce5cb954 353 Pfam PF08544 GHMP kinases C terminal 249 317 5.8E-13 T 30-10-2018 IPR013750 GHMP kinase, C-terminal domain CL1_1379 f90fcaabf544e0c5b7730006ce5cb954 353 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 96 107 - T 30-10-2018 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 CL1_1379 f90fcaabf544e0c5b7730006ce5cb954 353 Pfam PF10509 Galactokinase galactose-binding signature 4 38 9.0E-14 T 30-10-2018 IPR019539 Galactokinase galactose-binding domain GO:0005534 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CL1_1379 f90fcaabf544e0c5b7730006ce5cb954 353 TIGRFAM TIGR00131 gal_kin: galactokinase 3 349 1.4E-76 T 30-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CL1_1379 f90fcaabf544e0c5b7730006ce5cb954 353 PRINTS PR00473 Galactokinase signature 87 105 9.4E-19 T 30-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CL1_1379 f90fcaabf544e0c5b7730006ce5cb954 353 PRINTS PR00473 Galactokinase signature 234 248 9.4E-19 T 30-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CL1_1379 f90fcaabf544e0c5b7730006ce5cb954 353 PRINTS PR00473 Galactokinase signature 8 26 9.4E-19 T 30-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CL1_1379 f90fcaabf544e0c5b7730006ce5cb954 353 PRINTS PR00473 Galactokinase signature 67 78 9.4E-19 T 30-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CL1_1379 f90fcaabf544e0c5b7730006ce5cb954 353 PIRSF PIRSF000530 1 353 1.0E-98 T 30-10-2018 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CL1_1379 f90fcaabf544e0c5b7730006ce5cb954 353 Gene3D G3DSA:3.30.70.890 180 350 5.1E-58 T 30-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily CL1_1379 f90fcaabf544e0c5b7730006ce5cb954 353 Gene3D G3DSA:3.30.230.10 2 179 7.0E-55 T 30-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CL1_1379 f90fcaabf544e0c5b7730006ce5cb954 353 ProSitePatterns PS00106 Galactokinase signature. 8 19 - T 30-10-2018 IPR019741 Galactokinase, conserved site KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CL1_1091 6d3a9def269b5769b15d70948a14a50a 341 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 11 321 1.5E-58 T 30-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD CL1_1091 6d3a9def269b5769b15d70948a14a50a 341 TIGRFAM TIGR00374 TIGR00374: TIGR00374 family protein 11 336 3.2E-60 T 30-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD CL1_0496 4084887c2ea57c2acb77c44044f48862 544 Gene3D G3DSA:3.40.640.10 176 396 9.2E-203 T 30-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 CL1_0496 4084887c2ea57c2acb77c44044f48862 544 Gene3D G3DSA:3.90.1150.10 41 538 9.2E-203 T 30-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 CL1_0496 4084887c2ea57c2acb77c44044f48862 544 TIGRFAM TIGR03801 asp_4_decarbox: aspartate 4-decarboxylase 22 540 6.2E-219 T 30-10-2018 IPR022518 Aspartate 4-decarboxylase KEGG: 00220+2.6.1.1|KEGG: 00250+4.1.1.12+2.6.1.1|KEGG: 00270+4.1.1.12+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 CL1_0496 4084887c2ea57c2acb77c44044f48862 544 SUPERFAMILY SSF53383 130 536 1.28E-51 T 30-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase CL1_0496 4084887c2ea57c2acb77c44044f48862 544 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 326 339 - T 30-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 CL1_0496 4084887c2ea57c2acb77c44044f48862 544 Pfam PF00155 Aminotransferase class I and II 179 518 1.1E-26 T 30-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CL1_0496 4084887c2ea57c2acb77c44044f48862 544 Gene3D G3DSA:1.10.20.110 48 418 9.2E-203 T 30-10-2018 CL1_1205 cd597ff2f4aeba5031c19d5ff5bc7aac 375 Pfam PF01950 Fructose-1,6-bisphosphatase 6 372 2.4E-187 T 30-10-2018 IPR002803 Fructose-1,6-bisphosphatase, class V KEGG: 00010+4.1.2.13+3.1.3.11|KEGG: 00030+4.1.2.13+3.1.3.11|KEGG: 00051+4.1.2.13+3.1.3.11|KEGG: 00680+4.1.2.13+3.1.3.11|KEGG: 00710+4.1.2.13+3.1.3.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 CL1_1205 cd597ff2f4aeba5031c19d5ff5bc7aac 375 PIRSF PIRSF015647 5 375 2.4E-192 T 30-10-2018 IPR002803 Fructose-1,6-bisphosphatase, class V KEGG: 00010+4.1.2.13+3.1.3.11|KEGG: 00030+4.1.2.13+3.1.3.11|KEGG: 00051+4.1.2.13+3.1.3.11|KEGG: 00680+4.1.2.13+3.1.3.11|KEGG: 00710+4.1.2.13+3.1.3.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 CL1_1205 cd597ff2f4aeba5031c19d5ff5bc7aac 375 ProDom PD014260 DIHYDROOROTATE DEHYDROGENASE THERMOPHILE-SPECIFIC TA1428 ST0318 BLL2851 16-BISPHOSPHATASE APE1109 PF0613 MJ0299 6 371 0.0 T 30-10-2018 IPR002803 Fructose-1,6-bisphosphatase, class V KEGG: 00010+4.1.2.13+3.1.3.11|KEGG: 00030+4.1.2.13+3.1.3.11|KEGG: 00051+4.1.2.13+3.1.3.11|KEGG: 00680+4.1.2.13+3.1.3.11|KEGG: 00710+4.1.2.13+3.1.3.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 CL1_1205 cd597ff2f4aeba5031c19d5ff5bc7aac 375 Hamap MF_02067 Fructose-1,6-bisphosphate aldolase/phosphatase [fbp]. 5 372 62.129 T 30-10-2018 IPR002803 Fructose-1,6-bisphosphatase, class V KEGG: 00010+4.1.2.13+3.1.3.11|KEGG: 00030+4.1.2.13+3.1.3.11|KEGG: 00051+4.1.2.13+3.1.3.11|KEGG: 00680+4.1.2.13+3.1.3.11|KEGG: 00710+4.1.2.13+3.1.3.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 CL1_1205 cd597ff2f4aeba5031c19d5ff5bc7aac 375 SUPERFAMILY SSF111249 6 372 2.09E-178 T 30-10-2018 IPR036076 Fructose-1,6-bisphosphatase, class V superfamily KEGG: 00010+3.1.3.11+4.1.2.13|KEGG: 00030+3.1.3.11+4.1.2.13|KEGG: 00051+3.1.3.11+4.1.2.13|KEGG: 00680+3.1.3.11+4.1.2.13|KEGG: 00710+3.1.3.11+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 CL1_1449 f207bc11302e0e447889a67b3cc9f536 326 Pfam PF00005 ABC transporter 26 189 6.1E-25 T 30-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CL1_1449 f207bc11302e0e447889a67b3cc9f536 326 SMART SM00382 34 247 7.1E-12 T 30-10-2018 IPR003593 AAA+ ATPase domain CL1_1449 f207bc11302e0e447889a67b3cc9f536 326 Gene3D G3DSA:3.40.50.300 3 326 4.6E-98 T 30-10-2018 CL1_1449 f207bc11302e0e447889a67b3cc9f536 326 ProSitePatterns PS00211 ABC transporters family signature. 162 176 - T 30-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CL1_1449 f207bc11302e0e447889a67b3cc9f536 326 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 241 305 9.4E-21 T 30-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CL1_1449 f207bc11302e0e447889a67b3cc9f536 326 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 239 325 2.5E-31 T 30-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CL1_1449 f207bc11302e0e447889a67b3cc9f536 326 SUPERFAMILY SSF52540 34 323 5.98E-67 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_1257 f972322ca9ce7aacbaf1ce66891af466 178 ProDom PD068053 METHYLTRANSFERASE DNA METHYLATED-DNA--PROTEIN-CYSTEINE 6-O- O-6-METHYLGUANINE-DNA- REPAIR MGMT DAMAGE ALKYLTRANSFERASE METHYLGUANINE-DNA 1 96 6.0E-18 T 30-10-2018 IPR015236 Domain of unknown function DUF1938 GO:0005737 CL1_1257 f972322ca9ce7aacbaf1ce66891af466 178 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 139 145 - T 30-10-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 CL1_1257 f972322ca9ce7aacbaf1ce66891af466 178 Pfam PF09153 Domain of unknown function (DUF1938) 1 85 5.8E-23 T 30-10-2018 IPR015236 Domain of unknown function DUF1938 GO:0005737 CL1_1257 f972322ca9ce7aacbaf1ce66891af466 178 Gene3D G3DSA:1.10.10.10 89 174 2.9E-31 T 30-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CL1_1257 f972322ca9ce7aacbaf1ce66891af466 178 Gene3D G3DSA:3.30.160.70 1 88 7.8E-19 T 30-10-2018 CL1_1257 f972322ca9ce7aacbaf1ce66891af466 178 SUPERFAMILY SSF46767 90 169 1.19E-21 T 30-10-2018 IPR036217 Methylated DNA-protein cysteine methyltransferase, DNA binding domain Reactome: R-HSA-5657655 CL1_1257 f972322ca9ce7aacbaf1ce66891af466 178 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 91 169 1.0E-22 T 30-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CL1_1257 f972322ca9ce7aacbaf1ce66891af466 178 SUPERFAMILY SSF53155 1 88 9.02E-23 T 30-10-2018 IPR036631 Methylated DNA-protein cysteine methyltransferase domain superfamily GO:0003908|GO:0006281 Reactome: R-HSA-5657655 CL1_1257 f972322ca9ce7aacbaf1ce66891af466 178 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 90 167 7.7E-25 T 30-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CL1_1096 7e2ff8ef69d85720179c315f7ee2490b 755 SUPERFAMILY SSF82866 556 749 2.49E-36 T 30-10-2018 CL1_1096 7e2ff8ef69d85720179c315f7ee2490b 755 SUPERFAMILY SSF82866 143 363 4.58E-44 T 30-10-2018 CL1_1096 7e2ff8ef69d85720179c315f7ee2490b 755 TIGRFAM TIGR00921 2A067: efflux transporter, putative, hydrophobe/amphiphile efflux-3 (HAE3) family 12 744 9.7E-228 T 30-10-2018 IPR004767 Hydrophobe/amphiphile efflux-3 HAE3 CL1_1096 7e2ff8ef69d85720179c315f7ee2490b 755 Gene3D G3DSA:1.20.1640.10 583 753 1.2E-13 T 30-10-2018 CL1_1096 7e2ff8ef69d85720179c315f7ee2490b 755 Gene3D G3DSA:1.20.1640.10 192 372 2.2E-25 T 30-10-2018 CL1_1096 7e2ff8ef69d85720179c315f7ee2490b 755 Pfam PF03176 MMPL family 534 744 2.6E-21 T 30-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 CL1_1096 7e2ff8ef69d85720179c315f7ee2490b 755 Pfam PF03176 MMPL family 45 403 2.9E-37 T 30-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 CL1_0890 0fc41fe49538a69694dda02095a02a31 136 Gene3D G3DSA:3.40.50.150 1 136 2.8E-23 T 30-10-2018 CL1_0890 0fc41fe49538a69694dda02095a02a31 136 Pfam PF03686 Uncharacterised protein family (UPF0146) 4 131 7.6E-28 T 30-10-2018 IPR005353 Uncharacterised protein family UPF0146 CL1_0890 0fc41fe49538a69694dda02095a02a31 136 Hamap MF_00341 UPF0146 protein . 3 132 25.356 T 30-10-2018 IPR005353 Uncharacterised protein family UPF0146 CL1_0890 0fc41fe49538a69694dda02095a02a31 136 SUPERFAMILY SSF51735 14 97 2.24E-5 T 30-10-2018 IPR036291 NAD(P)-binding domain superfamily CL1_0890 0fc41fe49538a69694dda02095a02a31 136 ProDom PD021130 UPF0146 MJ0688 SIMILAR ARCHAEA UNCHARACTERIZED AF0739.1 MTH1000 PYRAB01940 PH0209 VNG2609C 19 112 4.0E-37 T 30-10-2018 IPR005353 Uncharacterised protein family UPF0146 CL1_1448 a0c94dfbb6da55522870a331d96a6ac3 391 SUPERFAMILY SSF161098 137 357 1.1E-30 T 30-10-2018 IPR035906 MetI-like superfamily CL1_1448 a0c94dfbb6da55522870a331d96a6ac3 391 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 44 98 1.7E-5 T 30-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain CL1_1448 a0c94dfbb6da55522870a331d96a6ac3 391 Gene3D G3DSA:1.10.3720.10 131 370 9.0E-29 T 30-10-2018 IPR035906 MetI-like superfamily CL1_1448 a0c94dfbb6da55522870a331d96a6ac3 391 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 160 375 5.8E-33 T 30-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 CL1_1364 d3ea29558748297613124645215a7604 290 Pfam PF06508 Queuosine biosynthesis protein QueC 54 275 2.4E-62 T 30-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 CL1_1364 d3ea29558748297613124645215a7604 290 TIGRFAM TIGR00364 TIGR00364: queuosine biosynthesis protein QueC 55 269 1.8E-47 T 30-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 CL1_1364 d3ea29558748297613124645215a7604 290 Gene3D G3DSA:3.40.50.620 51 286 9.9E-60 T 30-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CL1_1364 d3ea29558748297613124645215a7604 290 Hamap MF_01633 7-cyano-7-deazaguanine synthase [queC]. 53 282 45.626 T 30-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 CL1_1364 d3ea29558748297613124645215a7604 290 SUPERFAMILY SSF52402 52 287 2.21E-50 T 30-10-2018 CL1_0189 d0f661af980b3d46ec0fe2ffd75afdcc 166 PIRSF PIRSF004897 1 166 1.7E-68 T 30-10-2018 IPR014424 Uncharacterised conserved protein UCP004897, ACT- type CL1_0189 d0f661af980b3d46ec0fe2ffd75afdcc 166 SUPERFAMILY SSF55021 106 164 3.62E-7 T 30-10-2018 CL1_1722 b80b05ac724709e2ed9e3e8b7023b86c 678 Gene3D G3DSA:2.130.10.10 11 336 1.0E-19 T 30-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 CL1_1722 b80b05ac724709e2ed9e3e8b7023b86c 678 SMART SM00320 28 66 0.84 T 30-10-2018 IPR001680 WD40 repeat GO:0005515 CL1_1722 b80b05ac724709e2ed9e3e8b7023b86c 678 SMART SM00320 295 333 0.074 T 30-10-2018 IPR001680 WD40 repeat GO:0005515 CL1_1722 b80b05ac724709e2ed9e3e8b7023b86c 678 SMART SM00320 255 293 0.93 T 30-10-2018 IPR001680 WD40 repeat GO:0005515 CL1_1722 b80b05ac724709e2ed9e3e8b7023b86c 678 Pfam PF08308 PEGA domain 409 477 9.7E-13 T 30-10-2018 IPR013229 PEGA CL1_1722 b80b05ac724709e2ed9e3e8b7023b86c 678 Pfam PF08308 PEGA domain 337 404 3.8E-9 T 30-10-2018 IPR013229 PEGA CL1_1722 b80b05ac724709e2ed9e3e8b7023b86c 678 Pfam PF08308 PEGA domain 486 539 1.6E-14 T 30-10-2018 IPR013229 PEGA CL1_1722 b80b05ac724709e2ed9e3e8b7023b86c 678 SUPERFAMILY SSF50998 31 335 5.49E-27 T 30-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily CL1_1722 b80b05ac724709e2ed9e3e8b7023b86c 678 Pfam PF12894 Anaphase-promoting complex subunit 4 WD40 domain 275 334 1.4E-5 T 30-10-2018 IPR024977 Anaphase-promoting complex subunit 4, WD40 domain CL1_1644 86b3ec705a1061b5c87191bbc1805757 144 Hamap MF_00498 UPF0179 protein . 2 141 23.857 T 30-10-2018 IPR005369 Uncharacterised protein family UPF0179 CL1_1644 86b3ec705a1061b5c87191bbc1805757 144 ProDom PD016182 UPF0179 TK0790 TV1250 PAE0681 PF1381 AF2154 MA3685 VNG1401C MJ1627 PH1477 3 143 1.0E-65 T 30-10-2018 IPR005369 Uncharacterised protein family UPF0179 CL1_1644 86b3ec705a1061b5c87191bbc1805757 144 Pfam PF03684 Uncharacterised protein family (UPF0179) 4 139 1.2E-42 T 30-10-2018 IPR005369 Uncharacterised protein family UPF0179 CL1_1644 86b3ec705a1061b5c87191bbc1805757 144 PIRSF PIRSF006595 1 144 1.0E-50 T 30-10-2018 IPR005369 Uncharacterised protein family UPF0179 CL1_0647 2f407ab8922d2a3478d8bec13f856294 344 TIGRFAM TIGR03399 RNA_3prim_cycl: RNA 3'-phosphate cyclase 4 324 4.8E-129 T 30-10-2018 IPR017770 RNA 3'-terminal phosphate cyclase type 1 GO:0003963|GO:0006396 CL1_0647 2f407ab8922d2a3478d8bec13f856294 344 Gene3D G3DSA:3.65.10.20 5 321 1.2E-127 T 30-10-2018 IPR037136 RNA 3'-terminal phosphate cyclase domain superfamily CL1_0647 2f407ab8922d2a3478d8bec13f856294 344 Gene3D G3DSA:3.30.360.20 182 276 1.2E-127 T 30-10-2018 IPR036553 RNA 3'-terminal phosphate cyclase, insert domain superfamily CL1_0647 2f407ab8922d2a3478d8bec13f856294 344 Pfam PF05189 RNA 3'-terminal phosphate cyclase (RTC), insert domain 184 275 7.8E-23 T 30-10-2018 IPR013791 RNA 3'-terminal phosphate cyclase, insert domain CL1_0647 2f407ab8922d2a3478d8bec13f856294 344 SUPERFAMILY SSF52913 183 276 2.48E-24 T 30-10-2018 IPR036553 RNA 3'-terminal phosphate cyclase, insert domain superfamily CL1_0647 2f407ab8922d2a3478d8bec13f856294 344 PIRSF PIRSF005378 1 343 8.1E-112 T 30-10-2018 IPR000228 RNA 3'-terminal phosphate cyclase GO:0006396 CL1_0647 2f407ab8922d2a3478d8bec13f856294 344 SUPERFAMILY SSF55205 4 216 7.85E-68 T 30-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 CL1_0647 2f407ab8922d2a3478d8bec13f856294 344 ProSitePatterns PS01287 RNA 3'-terminal phosphate cyclase signature. 154 164 - T 30-10-2018 IPR020719 RNA 3'-terminal phosphate cyclase-like, conserved site CL1_0647 2f407ab8922d2a3478d8bec13f856294 344 Pfam PF01137 RNA 3'-terminal phosphate cyclase 10 326 1.0E-77 T 30-10-2018 IPR023797 RNA 3'-terminal phosphate cyclase domain CL1_0647 2f407ab8922d2a3478d8bec13f856294 344 Hamap MF_00200 RNA 3'-terminal phosphate cyclase [rtcA]. 3 338 40.193 T 30-10-2018 IPR017770 RNA 3'-terminal phosphate cyclase type 1 GO:0003963|GO:0006396 CL1_1989 333e20b621545c84c83466db98ed9c5c 553 Gene3D G3DSA:3.30.260.10 147 405 4.9E-218 T 30-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily CL1_1989 333e20b621545c84c83466db98ed9c5c 553 ProSitePatterns PS00995 Chaperonins TCP-1 signature 3. 89 97 - T 30-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 CL1_1989 333e20b621545c84c83466db98ed9c5c 553 ProSitePatterns PS00751 Chaperonins TCP-1 signature 2. 61 77 - T 30-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 CL1_1989 333e20b621545c84c83466db98ed9c5c 553 Gene3D G3DSA:1.10.560.10 28 522 4.9E-218 T 30-10-2018 IPR027413 GroEL-like equatorial domain superfamily CL1_1989 333e20b621545c84c83466db98ed9c5c 553 TIGRFAM TIGR02339 thermosome_arch: thermosome, various subunits, archaeal 8 525 1.7E-237 T 30-10-2018 IPR012714 Thermosome, archaeal GO:0005524|GO:0006457|GO:0051082 CL1_1989 333e20b621545c84c83466db98ed9c5c 553 SUPERFAMILY SSF48592 17 523 3.01E-91 T 30-10-2018 IPR027413 GroEL-like equatorial domain superfamily CL1_1989 333e20b621545c84c83466db98ed9c5c 553 Pfam PF00118 TCP-1/cpn60 chaperonin family 35 525 1.8E-183 T 30-10-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 CL1_1989 333e20b621545c84c83466db98ed9c5c 553 SUPERFAMILY SSF54849 149 405 1.1E-30 T 30-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily CL1_1989 333e20b621545c84c83466db98ed9c5c 553 ProSitePatterns PS00750 Chaperonins TCP-1 signature 1. 40 52 - T 30-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 CL1_1989 333e20b621545c84c83466db98ed9c5c 553 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 407 419 2.0E-34 T 30-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 CL1_1989 333e20b621545c84c83466db98ed9c5c 553 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 59 77 2.0E-34 T 30-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 CL1_1989 333e20b621545c84c83466db98ed9c5c 553 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 373 395 2.0E-34 T 30-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 CL1_1989 333e20b621545c84c83466db98ed9c5c 553 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 89 108 2.0E-34 T 30-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 CL1_1989 333e20b621545c84c83466db98ed9c5c 553 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 37 53 2.0E-34 T 30-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 CL1_1989 333e20b621545c84c83466db98ed9c5c 553 SUPERFAMILY SSF52029 212 378 1.11E-63 T 30-10-2018 IPR027409 GroEL-like apical domain superfamily CL1_1989 333e20b621545c84c83466db98ed9c5c 553 Gene3D G3DSA:3.50.7.10 218 369 4.9E-218 T 30-10-2018 IPR027409 GroEL-like apical domain superfamily CL1_0568 52b27f6ca033f3452df55d786ee3500e 263 Pfam PF00696 Amino acid kinase family 1 236 1.8E-41 T 30-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 CL1_0568 52b27f6ca033f3452df55d786ee3500e 263 Gene3D G3DSA:3.40.1160.10 1 262 9.6E-60 T 30-10-2018 IPR036393 Acetylglutamate kinase-like superfamily CL1_0568 52b27f6ca033f3452df55d786ee3500e 263 PIRSF PIRSF016496 1 263 4.9E-82 T 30-10-2018 IPR024192 Fosfomycin resistance kinase, FomA-type GO:0016301 KEGG: 00900+2.7.4.26|MetaCyc: PWY-6174|MetaCyc: PWY-7524 CL1_0568 52b27f6ca033f3452df55d786ee3500e 263 SUPERFAMILY SSF53633 1 261 2.09E-32 T 30-10-2018 IPR036393 Acetylglutamate kinase-like superfamily CL1_0246 54df041aec0f0d66b619bc37814ab829 267 SUPERFAMILY SSF47240 61 200 2.67E-15 T 30-10-2018 IPR009078 Ferritin-like superfamily CL1_0246 54df041aec0f0d66b619bc37814ab829 267 Pfam PF09968 Uncharacterized protein domain (DUF2202) 61 220 9.0E-68 T 30-10-2018 IPR019243 Domain of unknown function DUF2202 CL1_0246 54df041aec0f0d66b619bc37814ab829 267 Gene3D G3DSA:1.20.1260.10 56 227 2.5E-71 T 30-10-2018 IPR012347 Ferritin-like CL1_0353 51eac9628ff6d58511a3c8643dac513a 277 SUPERFAMILY SSF55729 1 144 8.67E-28 T 30-10-2018 IPR016181 Acyl-CoA N-acyltransferase CL1_0353 51eac9628ff6d58511a3c8643dac513a 277 Pfam PF00583 Acetyltransferase (GNAT) family 48 141 4.7E-16 T 30-10-2018 IPR000182 GNAT domain CL1_0353 51eac9628ff6d58511a3c8643dac513a 277 Gene3D G3DSA:3.40.630.30 1 158 1.4E-26 T 30-10-2018 CL1_0628 20539d20efc4475c8e2a12743910e9a2 347 Gene3D G3DSA:3.30.1430.10 77 188 2.8E-122 T 30-10-2018 CL1_0628 20539d20efc4475c8e2a12743910e9a2 347 SUPERFAMILY SSF50447 3 347 8.3E-96 T 30-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily CL1_0628 20539d20efc4475c8e2a12743910e9a2 347 Gene3D G3DSA:2.40.30.10 39 327 2.8E-122 T 30-10-2018 CL1_0628 20539d20efc4475c8e2a12743910e9a2 347 Pfam PF00297 Ribosomal protein L3 3 347 1.1E-89 T 30-10-2018 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CL1_0628 20539d20efc4475c8e2a12743910e9a2 347 Hamap MF_01325_A 50S ribosomal protein L3 [rplC]. 1 347 49.796 T 30-10-2018 IPR019928 Ribosomal protein L3, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 CL1_0628 20539d20efc4475c8e2a12743910e9a2 347 ProSitePatterns PS00474 Ribosomal protein L3 signature. 193 216 - T 30-10-2018 IPR019926 Ribosomal protein L3, conserved site CL1_0628 20539d20efc4475c8e2a12743910e9a2 347 Gene3D G3DSA:4.10.960.10 6 257 2.8E-122 T 30-10-2018 CL1_0628 20539d20efc4475c8e2a12743910e9a2 347 TIGRFAM TIGR03626 L3_arch: ribosomal protein uL3 5 346 1.2E-136 T 30-10-2018 IPR019928 Ribosomal protein L3, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 CL1_0016 328976f9e0672a7a4cc750cca86fcd75 153 Pfam PF01850 PIN domain 5 138 1.8E-16 T 30-10-2018 IPR002716 PIN domain CL1_0016 328976f9e0672a7a4cc750cca86fcd75 153 SUPERFAMILY SSF88723 2 137 1.54E-18 T 30-10-2018 IPR029060 PIN-like domain superfamily CL1_0016 328976f9e0672a7a4cc750cca86fcd75 153 Gene3D G3DSA:3.40.50.1010 3 152 3.5E-14 T 30-10-2018 CL1_0016 328976f9e0672a7a4cc750cca86fcd75 153 SMART SM00670 2 136 2.4E-7 T 30-10-2018 IPR002716 PIN domain CL1_1578 5f877851a31016c1941a701d20826243 150 Gene3D G3DSA:1.10.10.2700 1 150 2.5E-66 T 30-10-2018 IPR038111 Ribosomal protein S19e domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_1578 5f877851a31016c1941a701d20826243 150 Pfam PF01090 Ribosomal protein S19e 3 138 4.7E-59 T 30-10-2018 IPR001266 Ribosomal protein S19e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_1578 5f877851a31016c1941a701d20826243 150 Hamap MF_01474 30S ribosomal protein S19e [rps19e]. 1 148 38.058 T 30-10-2018 IPR027548 Ribosomal protein S19e, archaeal GO:0003735|GO:0005840|GO:0006412 CL1_1578 5f877851a31016c1941a701d20826243 150 ProSitePatterns PS00628 Ribosomal protein S19e signature. 87 106 - T 30-10-2018 IPR018277 Ribosomal protein S19e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_1578 5f877851a31016c1941a701d20826243 150 ProDom PD003854 RIBOSOMAL 40S RIBONUCLEOPROTEIN S19 S19E 30S MULTIGENE FAMILY S19 SSU 3 115 1.0E-57 T 30-10-2018 IPR001266 Ribosomal protein S19e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_1578 5f877851a31016c1941a701d20826243 150 SUPERFAMILY SSF46785 3 150 1.57E-61 T 30-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CL1_1578 5f877851a31016c1941a701d20826243 150 SMART SM01413 3 139 2.0E-92 T 30-10-2018 IPR001266 Ribosomal protein S19e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_1553 2e95615616f3dc58cf81147bdb0b9ac4 220 Gene3D G3DSA:3.60.110.10 1 219 1.6E-32 T 30-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily CL1_1553 2e95615616f3dc58cf81147bdb0b9ac4 220 Pfam PF00795 Carbon-nitrogen hydrolase 14 177 4.2E-17 T 30-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 CL1_1553 2e95615616f3dc58cf81147bdb0b9ac4 220 SUPERFAMILY SSF56317 1 214 4.19E-37 T 30-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily CL1_1485 3daaad0b2c29d17cf7132ac7f35cb951 164 Gene3D G3DSA:3.60.21.10 1 164 1.9E-40 T 30-10-2018 IPR029052 Metallo-dependent phosphatase-like CL1_1485 3daaad0b2c29d17cf7132ac7f35cb951 164 SUPERFAMILY SSF56300 2 162 1.31E-37 T 30-10-2018 CL1_1485 3daaad0b2c29d17cf7132ac7f35cb951 164 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 2 152 1.0E-25 T 30-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 CL1_1485 3daaad0b2c29d17cf7132ac7f35cb951 164 TIGRFAM TIGR00040 yfcE: phosphodiesterase, MJ0936 family 2 158 1.0E-33 T 30-10-2018 IPR000979 Phosphodiesterase MJ0936/Vps29 Reactome: R-HSA-3238698 CL1_1667 ac6277e618afe04d18f22e0f3a568502 472 SUPERFAMILY SSF51735 10 141 1.58E-38 T 30-10-2018 IPR036291 NAD(P)-binding domain superfamily CL1_1667 ac6277e618afe04d18f22e0f3a568502 472 Gene3D G3DSA:3.40.50.261 142 306 5.9E-60 T 30-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CL1_1667 ac6277e618afe04d18f22e0f3a568502 472 Gene3D G3DSA:3.40.50.261 308 470 3.8E-51 T 30-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CL1_1667 ac6277e618afe04d18f22e0f3a568502 472 SUPERFAMILY SSF52210 311 468 4.58E-40 T 30-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CL1_1667 ac6277e618afe04d18f22e0f3a568502 472 Pfam PF13380 CoA binding domain 16 145 5.8E-25 T 30-10-2018 IPR003781 CoA-binding GO:0048037 CL1_1667 ac6277e618afe04d18f22e0f3a568502 472 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 167 303 5.0E-56 T 30-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain CL1_1667 ac6277e618afe04d18f22e0f3a568502 472 SMART SM00881 12 111 4.5E-36 T 30-10-2018 IPR003781 CoA-binding GO:0048037 CL1_1667 ac6277e618afe04d18f22e0f3a568502 472 SUPERFAMILY SSF52210 143 304 2.62E-44 T 30-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CL1_1667 ac6277e618afe04d18f22e0f3a568502 472 Gene3D G3DSA:3.40.50.720 9 140 8.2E-43 T 30-10-2018 CL1_0135 8ab6cb8db0e12f041f6e37dc31c42cbb 190 SMART SM00116 141 187 1.5 T 30-10-2018 IPR000644 CBS domain CL1_0135 8ab6cb8db0e12f041f6e37dc31c42cbb 190 SMART SM00116 77 124 8.8E-7 T 30-10-2018 IPR000644 CBS domain CL1_0135 8ab6cb8db0e12f041f6e37dc31c42cbb 190 Pfam PF01381 Helix-turn-helix 13 60 1.4E-14 T 30-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CL1_0135 8ab6cb8db0e12f041f6e37dc31c42cbb 190 PIRSF PIRSF037253 2 190 5.3E-82 T 30-10-2018 IPR017158 Transcription regulator, CBS domain-containing, predicted CL1_0135 8ab6cb8db0e12f041f6e37dc31c42cbb 190 Gene3D G3DSA:1.10.260.40 10 63 6.9E-17 T 30-10-2018 CL1_0135 8ab6cb8db0e12f041f6e37dc31c42cbb 190 Gene3D G3DSA:3.10.580.10 64 186 5.5E-27 T 30-10-2018 CL1_0135 8ab6cb8db0e12f041f6e37dc31c42cbb 190 SMART SM00530 12 68 1.8E-14 T 30-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CL1_0135 8ab6cb8db0e12f041f6e37dc31c42cbb 190 Pfam PF00571 CBS domain 134 184 1.3E-6 T 30-10-2018 IPR000644 CBS domain CL1_0135 8ab6cb8db0e12f041f6e37dc31c42cbb 190 Pfam PF00571 CBS domain 70 121 6.5E-12 T 30-10-2018 IPR000644 CBS domain CL1_0135 8ab6cb8db0e12f041f6e37dc31c42cbb 190 SUPERFAMILY SSF54631 67 184 9.85E-27 T 30-10-2018 CL1_0135 8ab6cb8db0e12f041f6e37dc31c42cbb 190 SUPERFAMILY SSF47413 10 60 9.92E-15 T 30-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 CL1_0010 32c0aa0b0f1cca824bc840352c3ec6d1 170 SUPERFAMILY SSF53323 2 167 4.18E-42 T 30-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 CL1_0010 32c0aa0b0f1cca824bc840352c3ec6d1 170 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 9 166 2.2E-36 T 30-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 CL1_0010 32c0aa0b0f1cca824bc840352c3ec6d1 170 Gene3D G3DSA:3.40.920.10 1 170 2.2E-53 T 30-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 CL1_1230 edfc48169d6d4bae2f7302a50fe4038c 103 SUPERFAMILY SSF54913 2 101 1.71E-33 T 30-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta CL1_1230 edfc48169d6d4bae2f7302a50fe4038c 103 Pfam PF03091 CutA1 divalent ion tolerance protein 4 100 1.5E-31 T 30-10-2018 IPR004323 Divalent ion tolerance protein, CutA GO:0010038 CL1_1230 edfc48169d6d4bae2f7302a50fe4038c 103 Gene3D G3DSA:3.30.70.120 1 102 1.3E-36 T 30-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal CL1_1689 1b8b46277d1f7c333b30d5d7a31941d9 375 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 2 360 1.4E-33 T 30-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CL1_1689 1b8b46277d1f7c333b30d5d7a31941d9 375 Gene3D G3DSA:3.40.50.620 1 226 7.7E-60 T 30-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CL1_1689 1b8b46277d1f7c333b30d5d7a31941d9 375 PIRSF PIRSF006588 1 375 4.2E-131 T 30-10-2018 IPR023617 Tyrosine-tRNA ligase, archaeal/eukaryotic-type GO:0004831 KEGG: 00970+6.1.1.1 CL1_1689 1b8b46277d1f7c333b30d5d7a31941d9 375 Hamap MF_02009 Tyrosine--tRNA ligase [tyrS]. 5 359 47.938 T 30-10-2018 IPR023678 Tyrosine-tRNA ligase, type 4 GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CL1_1689 1b8b46277d1f7c333b30d5d7a31941d9 375 Gene3D G3DSA:1.10.240.10 227 375 7.8E-56 T 30-10-2018 CL1_1689 1b8b46277d1f7c333b30d5d7a31941d9 375 Pfam PF00579 tRNA synthetases class I (W and Y) 33 351 4.2E-44 T 30-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 CL1_1689 1b8b46277d1f7c333b30d5d7a31941d9 375 SUPERFAMILY SSF52374 1 363 1.02E-66 T 30-10-2018 CL1_0494 675cf3bd79bab0c0039a019c8c66d354 481 Gene3D G3DSA:1.10.287.70 395 481 2.7E-14 T 30-10-2018 CL1_0494 675cf3bd79bab0c0039a019c8c66d354 481 SUPERFAMILY SSF81324 394 480 1.02E-16 T 30-10-2018 CL1_0494 675cf3bd79bab0c0039a019c8c66d354 481 Pfam PF07885 Ion channel 402 480 1.9E-14 T 30-10-2018 IPR013099 Potassium channel domain CL1_1131 171566c8dd77a544528b5db2475730d8 425 Pfam PF00374 Nickel-dependent hydrogenase 46 114 7.2E-14 T 30-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 CL1_1131 171566c8dd77a544528b5db2475730d8 425 Gene3D G3DSA:1.10.645.20 8 380 2.3E-121 T 30-10-2018 IPR038290 NADH-quinone oxidoreductase, subunit D superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CL1_1131 171566c8dd77a544528b5db2475730d8 425 SUPERFAMILY SSF56762 17 380 8.37E-105 T 30-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CL1_1131 171566c8dd77a544528b5db2475730d8 425 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 121 380 4.8E-57 T 30-10-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CL1_1156 ae5b786b4bfa458ecc8fc1b497cda731 118 Pfam PF07883 Cupin domain 39 104 2.8E-13 T 30-10-2018 IPR013096 Cupin 2, conserved barrel CL1_1156 ae5b786b4bfa458ecc8fc1b497cda731 118 Gene3D G3DSA:2.60.120.10 4 117 1.6E-31 T 30-10-2018 IPR014710 RmlC-like jelly roll fold CL1_1156 ae5b786b4bfa458ecc8fc1b497cda731 118 SUPERFAMILY SSF51182 7 106 4.89E-26 T 30-10-2018 IPR011051 RmlC-like cupin domain superfamily CL1_0085 e6677a6a950bcda435affd39946c43e7 252 SUPERFAMILY SSF53218 1 202 1.14E-40 T 30-10-2018 IPR036425 MoaB/Mog-like domain superfamily CL1_0085 e6677a6a950bcda435affd39946c43e7 252 Pfam PF00994 Probable molybdopterin binding domain 4 176 1.5E-35 T 30-10-2018 IPR001453 MoaB/Mog domain CL1_0085 e6677a6a950bcda435affd39946c43e7 252 SMART SM00852 4 179 7.2E-44 T 30-10-2018 IPR001453 MoaB/Mog domain CL1_0085 e6677a6a950bcda435affd39946c43e7 252 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 3 174 1.9E-25 T 30-10-2018 IPR001453 MoaB/Mog domain CL1_0085 e6677a6a950bcda435affd39946c43e7 252 Gene3D G3DSA:3.40.980.10 2 179 9.8E-55 T 30-10-2018 IPR036425 MoaB/Mog-like domain superfamily CL1_0085 e6677a6a950bcda435affd39946c43e7 252 Hamap MF_00226_A Putative competence-damage inducible protein [cinA]. 1 249 39.247 T 30-10-2018 IPR023055 Putative competence-damage inducible protein, Archaea CL1_1171 2a85df30587a6186104abcc896b87d02 621 Gene3D G3DSA:2.120.10.30 19 138 2.0E-12 T 30-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like CL1_1171 2a85df30587a6186104abcc896b87d02 621 Gene3D G3DSA:3.40.50.1820 353 621 4.3E-83 T 30-10-2018 IPR029058 Alpha/Beta hydrolase fold CL1_1171 2a85df30587a6186104abcc896b87d02 621 SUPERFAMILY SSF82171 23 337 4.9E-22 T 30-10-2018 CL1_1171 2a85df30587a6186104abcc896b87d02 621 SUPERFAMILY SSF53474 352 605 3.63E-58 T 30-10-2018 IPR029058 Alpha/Beta hydrolase fold CL1_1171 2a85df30587a6186104abcc896b87d02 621 Pfam PF00326 Prolyl oligopeptidase family 397 605 2.5E-53 T 30-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 CL1_0163 ab2a7da1f4b1120111a46b665bca3ca1 151 ProSitePatterns PS00362 Ribosomal protein S15 signature. 98 128 - T 30-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CL1_0163 ab2a7da1f4b1120111a46b665bca3ca1 151 Hamap MF_01343_A 30S ribosomal protein S15 [rpsO]. 3 149 37.718 T 30-10-2018 IPR023029 Ribosomal protein S15P Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0163 ab2a7da1f4b1120111a46b665bca3ca1 151 Gene3D G3DSA:1.10.287.10 83 151 2.7E-32 T 30-10-2018 CL1_0163 ab2a7da1f4b1120111a46b665bca3ca1 151 SMART SM01387 70 149 9.7E-27 T 30-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CL1_0163 ab2a7da1f4b1120111a46b665bca3ca1 151 Pfam PF00312 Ribosomal protein S15 73 148 3.4E-20 T 30-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CL1_0163 ab2a7da1f4b1120111a46b665bca3ca1 151 SUPERFAMILY SSF47060 66 142 1.0E-24 T 30-10-2018 IPR009068 S15/NS1, RNA-binding CL1_0163 ab2a7da1f4b1120111a46b665bca3ca1 151 SMART SM01386 1 60 1.7E-34 T 30-10-2018 IPR012606 Ribosomal protein S13/S15, N-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0163 ab2a7da1f4b1120111a46b665bca3ca1 151 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 91 132 5.0E-4 T 30-10-2018 CL1_0163 ab2a7da1f4b1120111a46b665bca3ca1 151 Gene3D G3DSA:1.10.8.1030 36 82 2.9E-21 T 30-10-2018 CL1_0163 ab2a7da1f4b1120111a46b665bca3ca1 151 Pfam PF08069 Ribosomal S13/S15 N-terminal domain 1 60 4.2E-27 T 30-10-2018 IPR012606 Ribosomal protein S13/S15, N-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_1574 e8c2a61afe4a777b47dc1bc9b8889757 228 SMART SM00654 4 206 2.6E-103 T 30-10-2018 IPR002769 Translation initiation factor IF6 GO:0042256|GO:0043022 CL1_1574 e8c2a61afe4a777b47dc1bc9b8889757 228 Gene3D G3DSA:3.75.10.10 1 227 3.6E-78 T 30-10-2018 CL1_1574 e8c2a61afe4a777b47dc1bc9b8889757 228 PIRSF PIRSF006413 2 228 1.2E-77 T 30-10-2018 IPR002769 Translation initiation factor IF6 GO:0042256|GO:0043022 CL1_1574 e8c2a61afe4a777b47dc1bc9b8889757 228 Pfam PF01912 eIF-6 family 5 206 2.0E-68 T 30-10-2018 IPR002769 Translation initiation factor IF6 GO:0042256|GO:0043022 CL1_1574 e8c2a61afe4a777b47dc1bc9b8889757 228 TIGRFAM TIGR00323 eIF-6: putative translation initiation factor eIF-6 5 226 2.3E-64 T 30-10-2018 IPR002769 Translation initiation factor IF6 GO:0042256|GO:0043022 CL1_1574 e8c2a61afe4a777b47dc1bc9b8889757 228 SUPERFAMILY SSF55909 3 226 9.81E-74 T 30-10-2018 CL1_1574 e8c2a61afe4a777b47dc1bc9b8889757 228 Hamap MF_00032 Translation initiation factor 6 [eif6]. 1 228 95.956 T 30-10-2018 IPR002769 Translation initiation factor IF6 GO:0042256|GO:0043022 CL1_0581 02eac917998039424c773e409d587aa9 149 Pfam PF13412 Winged helix-turn-helix DNA-binding 1 48 6.7E-19 T 30-10-2018 CL1_0581 02eac917998039424c773e409d587aa9 149 Gene3D G3DSA:1.10.10.10 1 51 4.2E-22 T 30-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CL1_0581 02eac917998039424c773e409d587aa9 149 Pfam PF01037 Lrp/AsnC ligand binding domain 67 136 8.4E-15 T 30-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CL1_0581 02eac917998039424c773e409d587aa9 149 SUPERFAMILY SSF54909 61 145 1.29E-17 T 30-10-2018 IPR011008 Dimeric alpha-beta barrel CL1_0581 02eac917998039424c773e409d587aa9 149 Gene3D G3DSA:3.30.70.920 53 146 4.1E-22 T 30-10-2018 CL1_0581 02eac917998039424c773e409d587aa9 149 SUPERFAMILY SSF46785 1 61 1.56E-17 T 30-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CL1_0581 02eac917998039424c773e409d587aa9 149 SMART SM00344 1 107 3.0E-44 T 30-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CL1_0581 02eac917998039424c773e409d587aa9 149 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 1.1E-13 T 30-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 CL1_0581 02eac917998039424c773e409d587aa9 149 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 1.1E-13 T 30-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 CL1_0581 02eac917998039424c773e409d587aa9 149 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 1.1E-13 T 30-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 CL1_2016 51bfc6e9e74a217fa5a469c17a5a3aad 179 Pfam PF12804 MobA-like NTP transferase domain 1 121 1.4E-10 T 30-10-2018 IPR025877 MobA-like NTP transferase CL1_2016 51bfc6e9e74a217fa5a469c17a5a3aad 179 SUPERFAMILY SSF53448 3 159 1.74E-12 T 30-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases CL1_2016 51bfc6e9e74a217fa5a469c17a5a3aad 179 Gene3D G3DSA:3.90.550.10 1 163 8.6E-21 T 30-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases CL1_1468 de3de9eace9c19bb2b65c157278882a6 256 Gene3D G3DSA:3.40.50.300 1 255 3.0E-73 T 30-10-2018 CL1_1468 de3de9eace9c19bb2b65c157278882a6 256 Pfam PF13614 AAA domain 4 178 8.0E-54 T 30-10-2018 IPR025669 AAA domain CL1_1468 de3de9eace9c19bb2b65c157278882a6 256 PIRSF PIRSF009320 2 47 1.2E-14 T 30-10-2018 CL1_1468 de3de9eace9c19bb2b65c157278882a6 256 PIRSF PIRSF009320 91 256 1.8E-6 T 30-10-2018 CL1_1468 de3de9eace9c19bb2b65c157278882a6 256 SUPERFAMILY SSF52540 1 254 4.89E-60 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_1758 bf800c7864b9276d3283d6a8b8f7c3a8 254 Pfam PF01026 TatD related DNase 2 248 2.2E-57 T 30-10-2018 IPR001130 TatD family GO:0016788 CL1_1758 bf800c7864b9276d3283d6a8b8f7c3a8 254 TIGRFAM TIGR00010 TIGR00010: hydrolase, TatD family 1 249 2.9E-68 T 30-10-2018 IPR015991 Uncharacterised hydrolase TatD-type GO:0004536 CL1_1758 bf800c7864b9276d3283d6a8b8f7c3a8 254 Gene3D G3DSA:3.20.20.140 1 251 4.8E-64 T 30-10-2018 CL1_1758 bf800c7864b9276d3283d6a8b8f7c3a8 254 SUPERFAMILY SSF51556 1 250 6.82E-57 T 30-10-2018 IPR032466 Metal-dependent hydrolase CL1_1758 bf800c7864b9276d3283d6a8b8f7c3a8 254 PIRSF PIRSF005902 1 253 7.1E-60 T 30-10-2018 IPR001130 TatD family GO:0016788 CL1_0123 14c5adef4dfeca693b2a9b5b262d6111 389 Gene3D G3DSA:3.90.1150.10 29 378 1.5E-153 T 30-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 CL1_0123 14c5adef4dfeca693b2a9b5b262d6111 389 Pfam PF00155 Aminotransferase class I and II 28 378 6.7E-80 T 30-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CL1_0123 14c5adef4dfeca693b2a9b5b262d6111 389 Gene3D G3DSA:3.40.640.10 58 280 1.5E-153 T 30-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 CL1_0123 14c5adef4dfeca693b2a9b5b262d6111 389 SUPERFAMILY SSF53383 2 385 4.71E-125 T 30-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase CL1_0123 14c5adef4dfeca693b2a9b5b262d6111 389 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 230 243 - T 30-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 CL1_0970 bd400087977b4acc8e3bb4ede6347e9b 307 Gene3D G3DSA:3.40.50.620 3 306 3.7E-92 T 30-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CL1_0970 bd400087977b4acc8e3bb4ede6347e9b 307 PIRSF PIRSF004976 1 302 1.4E-96 T 30-10-2018 IPR035107 tRNA thiolation protein, TtcA/Ctu1 type GO:0008033 Reactome: R-HSA-6782315 CL1_0970 bd400087977b4acc8e3bb4ede6347e9b 307 TIGRFAM TIGR00269 TIGR00269: TIGR00269 family protein 194 293 2.3E-25 T 30-10-2018 IPR000541 Cytoplasmic tRNA 2-thiolation protein 1 GO:0000049|GO:0002098|GO:0034227 Reactome: R-HSA-6782315 CL1_0970 bd400087977b4acc8e3bb4ede6347e9b 307 Pfam PF01171 PP-loop family 52 221 1.1E-12 T 30-10-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 CL1_0970 bd400087977b4acc8e3bb4ede6347e9b 307 SUPERFAMILY SSF52402 26 247 2.43E-52 T 30-10-2018 CL1_0805 29c8c684f5adef3aae7c134acd70d072 151 SUPERFAMILY SSF50118 7 121 1.53E-16 T 30-10-2018 CL1_0805 29c8c684f5adef3aae7c134acd70d072 151 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 9 120 8.9E-15 T 30-10-2018 IPR003477 mRNA interferase PemK-like GO:0003677 CL1_0805 29c8c684f5adef3aae7c134acd70d072 151 Gene3D G3DSA:2.30.30.110 20 123 3.3E-18 T 30-10-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor CL1_1128 ac835988056df2329b3f0ec24a8a2298 170 Pfam PF02915 Rubrerythrin 104 161 7.4E-5 T 30-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 CL1_1128 ac835988056df2329b3f0ec24a8a2298 170 SUPERFAMILY SSF47240 15 157 1.19E-19 T 30-10-2018 IPR009078 Ferritin-like superfamily CL1_1128 ac835988056df2329b3f0ec24a8a2298 170 Gene3D G3DSA:1.20.1260.10 8 154 5.4E-20 T 30-10-2018 IPR012347 Ferritin-like CL1_1747 ac7204bf32b6fd06db3000d0197ae748 464 Pfam PF09339 IclR helix-turn-helix domain 249 292 2.2E-7 T 30-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CL1_1747 ac7204bf32b6fd06db3000d0197ae748 464 Gene3D G3DSA:3.40.50.300 1 173 1.2E-32 T 30-10-2018 CL1_1747 ac7204bf32b6fd06db3000d0197ae748 464 Pfam PF01637 ATPase domain predominantly from Archaea 6 208 1.6E-26 T 30-10-2018 IPR011579 ATPase domain GO:0005524 CL1_1747 ac7204bf32b6fd06db3000d0197ae748 464 Gene3D G3DSA:1.10.10.10 246 322 6.6E-6 T 30-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CL1_1747 ac7204bf32b6fd06db3000d0197ae748 464 SUPERFAMILY SSF52540 4 248 1.13E-38 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_1747 ac7204bf32b6fd06db3000d0197ae748 464 SUPERFAMILY SSF46785 247 325 6.5E-10 T 30-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CL1_1747 ac7204bf32b6fd06db3000d0197ae748 464 Pfam PF03008 Archaea bacterial proteins of unknown function 318 414 1.7E-24 T 30-10-2018 IPR004256 Domain of unknown function DUF234, DEXX-box ATPase C-terminal CL1_1725 34d17435748839480d0af3aa9f69d7ba 398 SUPERFAMILY SSF52540 116 396 2.91E-55 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_1725 34d17435748839480d0af3aa9f69d7ba 398 Gene3D G3DSA:3.40.50.300 114 393 2.6E-87 T 30-10-2018 CL1_1725 34d17435748839480d0af3aa9f69d7ba 398 ProSitePatterns PS00674 AAA-protein family signature. 256 275 - T 30-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 CL1_1725 34d17435748839480d0af3aa9f69d7ba 398 SMART SM00382 149 286 1.2E-16 T 30-10-2018 IPR003593 AAA+ ATPase domain CL1_1725 34d17435748839480d0af3aa9f69d7ba 398 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 153 284 2.3E-39 T 30-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CL1_1725 34d17435748839480d0af3aa9f69d7ba 398 Pfam PF09336 Vps4 C terminal oligomerisation domain 354 397 1.4E-7 T 30-10-2018 IPR015415 Vps4 oligomerisation, C-terminal CL1_1725 34d17435748839480d0af3aa9f69d7ba 398 Gene3D G3DSA:1.10.8.60 285 377 2.6E-87 T 30-10-2018 CL1_0305 3ce308aff177e64cb145dfc239e44791 225 Gene3D G3DSA:3.90.79.30 100 219 4.9E-63 T 30-10-2018 CL1_0305 3ce308aff177e64cb145dfc239e44791 225 Pfam PF15517 TBP-interacting protein N-terminus 3 101 7.4E-45 T 30-10-2018 IPR029125 TBP-interacting protein, N-terminal CL1_0305 3ce308aff177e64cb145dfc239e44791 225 SUPERFAMILY SSF159612 2 218 1.06E-112 T 30-10-2018 CL1_0305 3ce308aff177e64cb145dfc239e44791 225 Gene3D G3DSA:3.40.1350.70 1 99 3.5E-49 T 30-10-2018 IPR038230 TBP-interacting protein, N-terminal superfamily CL1_0030 7e1140a246e04eff281dcae7774fc630 350 Gene3D G3DSA:3.10.50.80 3 166 3.0E-50 T 30-10-2018 CL1_0030 7e1140a246e04eff281dcae7774fc630 350 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 4 154 1.8E-16 T 30-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain CL1_0030 7e1140a246e04eff281dcae7774fc630 350 SUPERFAMILY SSF54534 3 156 4.32E-40 T 30-10-2018 CL1_1905 c9b8c96f6c288cceab21d8f37822d8d9 602 Pfam PF01380 SIS domain 284 412 4.8E-33 T 30-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CL1_1905 c9b8c96f6c288cceab21d8f37822d8d9 602 Pfam PF01380 SIS domain 458 584 2.9E-22 T 30-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CL1_1905 c9b8c96f6c288cceab21d8f37822d8d9 602 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 602 7.8E-246 T 30-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 CL1_1905 c9b8c96f6c288cceab21d8f37822d8d9 602 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 602 40.884 T 30-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 CL1_1905 c9b8c96f6c288cceab21d8f37822d8d9 602 Gene3D G3DSA:3.60.20.10 2 242 1.4E-76 T 30-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CL1_1905 c9b8c96f6c288cceab21d8f37822d8d9 602 Gene3D G3DSA:3.40.50.10490 442 587 1.1E-137 T 30-10-2018 CL1_1905 c9b8c96f6c288cceab21d8f37822d8d9 602 SUPERFAMILY SSF53697 247 602 1.76E-111 T 30-10-2018 CL1_1905 c9b8c96f6c288cceab21d8f37822d8d9 602 Gene3D G3DSA:3.40.50.10490 251 601 1.1E-137 T 30-10-2018 CL1_1905 c9b8c96f6c288cceab21d8f37822d8d9 602 Pfam PF13522 Glutamine amidotransferase domain 66 193 1.6E-20 T 30-10-2018 CL1_1905 c9b8c96f6c288cceab21d8f37822d8d9 602 SUPERFAMILY SSF56235 2 226 1.12E-72 T 30-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CL1_0332 59c010ac246a6208e9c7613484dfc2cc 263 Gene3D G3DSA:1.10.1670.10 21 251 1.1E-80 T 30-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 CL1_0332 59c010ac246a6208e9c7613484dfc2cc 263 SUPERFAMILY SSF48150 16 253 9.42E-80 T 30-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CL1_0332 59c010ac246a6208e9c7613484dfc2cc 263 Hamap MF_01168 N-glycosylase/DNA lyase. 20 257 38.953 T 30-10-2018 IPR016544 N-glycosylase/DNA lyase GO:0000702|GO:0003906|GO:0006284 CL1_0332 59c010ac246a6208e9c7613484dfc2cc 263 Pfam PF09171 N-glycosylase/DNA lyase 23 243 2.2E-83 T 30-10-2018 IPR015254 N-glycosylase/DNA lyase-like GO:0003906|GO:0016799 CL1_0332 59c010ac246a6208e9c7613484dfc2cc 263 Gene3D G3DSA:1.10.340.30 41 188 1.1E-80 T 30-10-2018 CL1_0332 59c010ac246a6208e9c7613484dfc2cc 263 PIRSF PIRSF008955 12 263 2.3E-100 T 30-10-2018 IPR016544 N-glycosylase/DNA lyase GO:0000702|GO:0003906|GO:0006284 CL1_1231 ff19d4ab3c3f259c7460eda4c77a78f2 91 ProSitePatterns PS00151 Acylphosphatase signature 2. 34 50 - T 30-10-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 CL1_1231 ff19d4ab3c3f259c7460eda4c77a78f2 91 Gene3D G3DSA:3.30.70.100 1 91 8.2E-38 T 30-10-2018 CL1_1231 ff19d4ab3c3f259c7460eda4c77a78f2 91 ProSitePatterns PS00150 Acylphosphatase signature 1. 10 20 - T 30-10-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 CL1_1231 ff19d4ab3c3f259c7460eda4c77a78f2 91 Pfam PF00708 Acylphosphatase 7 88 5.2E-28 T 30-10-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 CL1_1231 ff19d4ab3c3f259c7460eda4c77a78f2 91 SUPERFAMILY SSF54975 2 89 2.62E-31 T 30-10-2018 IPR036046 Acylphosphatase-like domain superfamily KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 CL1_1231 ff19d4ab3c3f259c7460eda4c77a78f2 91 PRINTS PR00112 Acylphosphatase signature 5 20 1.9E-9 T 30-10-2018 IPR020456 Acylphosphatase GO:0003998 KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 CL1_1231 ff19d4ab3c3f259c7460eda4c77a78f2 91 PRINTS PR00112 Acylphosphatase signature 26 51 1.9E-9 T 30-10-2018 IPR020456 Acylphosphatase GO:0003998 KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 CL1_1531 250c0a670a003ed3e5bd31e9f477b41e 112 PIRSF PIRSF016134 2 111 8.1E-45 T 30-10-2018 IPR016645 Uncharacterised conserved protein UCP016134 CL1_1531 250c0a670a003ed3e5bd31e9f477b41e 112 SUPERFAMILY SSF88697 1 108 3.36E-31 T 30-10-2018 IPR015947 PUA-like superfamily CL1_1531 250c0a670a003ed3e5bd31e9f477b41e 112 SMART SM01022 6 109 2.9E-13 T 30-10-2018 IPR007374 ASCH domain CL1_1531 250c0a670a003ed3e5bd31e9f477b41e 112 Pfam PF04266 ASCH domain 6 107 6.7E-14 T 30-10-2018 IPR007374 ASCH domain CL1_1531 250c0a670a003ed3e5bd31e9f477b41e 112 Gene3D G3DSA:2.30.130.30 1 112 1.1E-39 T 30-10-2018 CL1_0382 bf3af16cdc337fc96b7c35b5ce77a9b3 235 Gene3D G3DSA:3.90.320.10 6 235 2.4E-17 T 30-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal CL1_2020 b94572f8e5c465832a855ef5e905b690 138 SUPERFAMILY SSF101307 6 135 1.2E-35 T 30-10-2018 IPR036681 PgpA-like superfamily GO:0006629|GO:0008962 CL1_2020 b94572f8e5c465832a855ef5e905b690 138 Pfam PF04608 Phosphatidylglycerophosphatase A 15 133 3.9E-10 T 30-10-2018 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 CL1_2020 b94572f8e5c465832a855ef5e905b690 138 TIGRFAM TIGR03161 ribazole_CobZ: alpha-ribazole phosphatase CobZ 10 134 4.2E-53 T 30-10-2018 IPR017577 Alpha-ribazole phosphatase, CobZ CL1_2020 b94572f8e5c465832a855ef5e905b690 138 Gene3D G3DSA:1.10.3760.10 3 138 2.9E-13 T 30-10-2018 CL1_0640 e24600506ed2e38d4939f1153ae701da 154 ProSitePatterns PS01099 Respiratory-chain NADH dehydrogenase 24 Kd subunit signature. 105 123 - T 30-10-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CL1_0640 e24600506ed2e38d4939f1153ae701da 154 Gene3D G3DSA:3.40.30.10 66 153 2.7E-31 T 30-10-2018 CL1_0640 e24600506ed2e38d4939f1153ae701da 154 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 8 147 4.1E-53 T 30-10-2018 CL1_0640 e24600506ed2e38d4939f1153ae701da 154 TIGRFAM TIGR01958 nuoE_fam: NADH-quinone oxidoreductase, E subunit 9 147 8.2E-43 T 30-10-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CL1_0640 e24600506ed2e38d4939f1153ae701da 154 SUPERFAMILY SSF52833 7 151 1.27E-52 T 30-10-2018 IPR036249 Thioredoxin-like superfamily CL1_0640 e24600506ed2e38d4939f1153ae701da 154 Gene3D G3DSA:1.10.10.1590 2 65 1.7E-20 T 30-10-2018 CL1_0640 e24600506ed2e38d4939f1153ae701da 154 PIRSF PIRSF000216 3 154 3.8E-59 T 30-10-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CL1_0009 796f0cc018ee1567688daa58a9576430 382 SUPERFAMILY SSF52518 12 265 4.37E-71 T 30-10-2018 IPR029061 Thiamin diphosphate-binding fold CL1_0009 796f0cc018ee1567688daa58a9576430 382 Gene3D G3DSA:3.40.50.970 1 199 2.0E-84 T 30-10-2018 CL1_0009 796f0cc018ee1567688daa58a9576430 382 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 282 376 5.0E-19 T 30-10-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II CL1_0009 796f0cc018ee1567688daa58a9576430 382 SUPERFAMILY SSF52922 274 378 4.58E-25 T 30-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 CL1_0009 796f0cc018ee1567688daa58a9576430 382 Gene3D G3DSA:3.40.50.920 272 381 2.8E-23 T 30-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 CL1_0009 796f0cc018ee1567688daa58a9576430 382 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 22 258 3.5E-81 T 30-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 CL1_0080 a5262d4386edda63ef6975c89321efc0 122 Gene3D G3DSA:3.30.450.30 6 122 8.6E-24 T 30-10-2018 CL1_0080 a5262d4386edda63ef6975c89321efc0 122 SMART SM00960 8 97 3.1E-16 T 30-10-2018 IPR004942 Roadblock/LAMTOR2 domain CL1_0080 a5262d4386edda63ef6975c89321efc0 122 SUPERFAMILY SSF103196 8 118 1.44E-20 T 30-10-2018 CL1_0080 a5262d4386edda63ef6975c89321efc0 122 Pfam PF03259 Roadblock/LC7 domain 11 96 4.6E-13 T 30-10-2018 IPR004942 Roadblock/LAMTOR2 domain CL1_0600 ca949c810d9b9778fafbfc5de15c2691 197 Hamap MF_00239 Cytidylate kinase [cmk]. 6 178 47.915 T 30-10-2018 IPR011892 Cytidylate kinase, putative GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 CL1_0600 ca949c810d9b9778fafbfc5de15c2691 197 SUPERFAMILY SSF52540 3 176 5.74E-22 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_0600 ca949c810d9b9778fafbfc5de15c2691 197 TIGRFAM TIGR02173 cyt_kin_arch: putative cytidylate kinase 6 175 1.3E-62 T 30-10-2018 IPR011892 Cytidylate kinase, putative GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 CL1_0600 ca949c810d9b9778fafbfc5de15c2691 197 Pfam PF13189 Cytidylate kinase-like family 7 160 2.7E-24 T 30-10-2018 CL1_0600 ca949c810d9b9778fafbfc5de15c2691 197 Gene3D G3DSA:3.40.50.300 2 177 3.5E-44 T 30-10-2018 CL1_2039 39905c54497d145dd5fdef03bb2d6d9d 177 Pfam PF02441 Flavoprotein 1 156 6.6E-29 T 30-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CL1_2039 39905c54497d145dd5fdef03bb2d6d9d 177 SUPERFAMILY SSF52507 1 176 1.96E-59 T 30-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 CL1_2039 39905c54497d145dd5fdef03bb2d6d9d 177 Hamap MF_01984 Flavin prenyltransferase UbiX [ubiX]. 1 177 37.899 T 30-10-2018 IPR004507 Flavin prenyltransferase UbiX-like CL1_2039 39905c54497d145dd5fdef03bb2d6d9d 177 TIGRFAM TIGR00421 ubiX_pad: polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylases 2 175 2.5E-73 T 30-10-2018 IPR004507 Flavin prenyltransferase UbiX-like CL1_2039 39905c54497d145dd5fdef03bb2d6d9d 177 Gene3D G3DSA:3.40.50.1950 1 177 1.3E-74 T 30-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 CL1_1181 20877940032bdb217de8c4e63a0b2bad 249 SUPERFAMILY SSF55681 1 246 3.98E-69 T 30-10-2018 CL1_1181 20877940032bdb217de8c4e63a0b2bad 249 Gene3D G3DSA:3.30.930.10 8 249 8.1E-63 T 30-10-2018 CL1_1181 20877940032bdb217de8c4e63a0b2bad 249 Pfam PF03099 Biotin/lipoate A/B protein ligase family 54 157 6.8E-14 T 30-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 CL1_1598 5fef1f3c65a7db05b1618b247bfd7eb8 339 Pfam PF01300 Telomere recombination 22 196 2.0E-60 T 30-10-2018 IPR006070 YrdC-like domain GO:0003725 CL1_1598 5fef1f3c65a7db05b1618b247bfd7eb8 339 Gene3D G3DSA:3.90.870.10 3 211 1.6E-84 T 30-10-2018 CL1_1598 5fef1f3c65a7db05b1618b247bfd7eb8 339 PIRSF PIRSF004930 1 338 2.6E-131 T 30-10-2018 IPR010923 tRNA threonylcarbamoyladenosine biosynthesis protein SUA5 CL1_1598 5fef1f3c65a7db05b1618b247bfd7eb8 339 Gene3D G3DSA:3.40.50.11030 216 339 2.2E-39 T 30-10-2018 IPR038385 Threonylcarbamoyl-AMP synthase, C-terminal domain superfamily CL1_1598 5fef1f3c65a7db05b1618b247bfd7eb8 339 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 11 207 1.3E-66 T 30-10-2018 IPR006070 YrdC-like domain GO:0003725 CL1_1598 5fef1f3c65a7db05b1618b247bfd7eb8 339 SUPERFAMILY SSF55821 8 209 4.88E-68 T 30-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily CL1_1598 5fef1f3c65a7db05b1618b247bfd7eb8 339 Pfam PF03481 Putative GTP-binding controlling metal-binding 200 333 5.9E-28 T 30-10-2018 IPR005145 Putative GTP-binding controlling metal-binding domain CL1_1673 fb367557a16c7dc1013973696f2db161 238 Gene3D G3DSA:1.10.340.30 40 153 3.6E-63 T 30-10-2018 CL1_1673 fb367557a16c7dc1013973696f2db161 238 SUPERFAMILY SSF48150 21 229 3.61E-62 T 30-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CL1_1673 fb367557a16c7dc1013973696f2db161 238 Pfam PF00633 Helix-hairpin-helix motif 120 149 1.6E-6 T 30-10-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 CL1_1673 fb367557a16c7dc1013973696f2db161 238 Hamap MF_00942 Endonuclease III [nth]. 21 231 33.311 T 30-10-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 CL1_1673 fb367557a16c7dc1013973696f2db161 238 SMART SM00478 57 207 1.1E-57 T 30-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CL1_1673 fb367557a16c7dc1013973696f2db161 238 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 53 190 2.0E-17 T 30-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CL1_1673 fb367557a16c7dc1013973696f2db161 238 SMART SM00525 208 228 3.8E-6 T 30-10-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 CL1_1673 fb367557a16c7dc1013973696f2db161 238 Gene3D G3DSA:1.10.1670.10 37 225 3.6E-63 T 30-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 CL1_1673 fb367557a16c7dc1013973696f2db161 238 PIRSF PIRSF001435 19 231 5.7E-40 T 30-10-2018 CL1_1673 fb367557a16c7dc1013973696f2db161 238 ProSitePatterns PS01155 Endonuclease III family signature. 123 152 - T 30-10-2018 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 CL1_1673 fb367557a16c7dc1013973696f2db161 238 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 209 225 - T 30-10-2018 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 CL1_0826 668c23d3fc5eb441f80ae24dd3dfd331 315 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 134 220 2.7E-9 T 30-10-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 CL1_0826 668c23d3fc5eb441f80ae24dd3dfd331 315 SUPERFAMILY SSF51735 2 150 8.79E-47 T 30-10-2018 IPR036291 NAD(P)-binding domain superfamily CL1_0826 668c23d3fc5eb441f80ae24dd3dfd331 315 Gene3D G3DSA:3.30.360.10 124 315 7.3E-48 T 30-10-2018 CL1_0826 668c23d3fc5eb441f80ae24dd3dfd331 315 SUPERFAMILY SSF55347 127 290 4.58E-31 T 30-10-2018 CL1_0826 668c23d3fc5eb441f80ae24dd3dfd331 315 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 2 122 8.5E-30 T 30-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 CL1_0826 668c23d3fc5eb441f80ae24dd3dfd331 315 Gene3D G3DSA:3.40.50.720 1 123 6.8E-33 T 30-10-2018 CL1_0762 f410e3de34f2470d87a821aaf25386ff 55 SMART SM01402 8 50 2.2E-23 T 30-10-2018 IPR002906 Ribosomal protein S27a GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 CL1_0762 f410e3de34f2470d87a821aaf25386ff 55 Hamap MF_00777 30S ribosomal protein S27ae [rps27ae]. 8 53 19.427 T 30-10-2018 IPR022845 Ribosomal protein S27ae CL1_0762 f410e3de34f2470d87a821aaf25386ff 55 Pfam PF01599 Ribosomal protein S27a 9 50 3.1E-21 T 30-10-2018 IPR002906 Ribosomal protein S27a GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 CL1_0762 f410e3de34f2470d87a821aaf25386ff 55 SUPERFAMILY SSF57829 8 54 7.51E-21 T 30-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 CL1_0762 f410e3de34f2470d87a821aaf25386ff 55 Gene3D G3DSA:2.20.25.660 1 53 1.0E-19 T 30-10-2018 IPR038582 S27a-like superfamily Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 CL1_2038 775b02f30b5f664dbaf8f3ab7252c035 160 SUPERFAMILY SSF46785 3 58 3.4E-14 T 30-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CL1_2038 775b02f30b5f664dbaf8f3ab7252c035 160 Pfam PF13412 Winged helix-turn-helix DNA-binding 4 50 4.4E-16 T 30-10-2018 CL1_2038 775b02f30b5f664dbaf8f3ab7252c035 160 SMART SM00344 4 105 4.0E-9 T 30-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CL1_2038 775b02f30b5f664dbaf8f3ab7252c035 160 Gene3D G3DSA:3.30.70.920 57 160 4.0E-32 T 30-10-2018 CL1_2038 775b02f30b5f664dbaf8f3ab7252c035 160 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 4 20 1.3E-13 T 30-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 CL1_2038 775b02f30b5f664dbaf8f3ab7252c035 160 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 31 50 1.3E-13 T 30-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 CL1_2038 775b02f30b5f664dbaf8f3ab7252c035 160 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 20 31 1.3E-13 T 30-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 CL1_2038 775b02f30b5f664dbaf8f3ab7252c035 160 Gene3D G3DSA:1.10.10.10 1 56 1.1E-24 T 30-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CL1_0663 aa9e72c4ed80fae2d93722b565fc4a7a 174 Pfam PF04266 ASCH domain 6 81 1.8E-6 T 30-10-2018 IPR007374 ASCH domain CL1_0663 aa9e72c4ed80fae2d93722b565fc4a7a 174 SMART SM01022 5 105 4.7E-7 T 30-10-2018 IPR007374 ASCH domain CL1_0663 aa9e72c4ed80fae2d93722b565fc4a7a 174 SUPERFAMILY SSF88697 3 145 1.66E-16 T 30-10-2018 IPR015947 PUA-like superfamily CL1_1714 eb7dfef83aa23786af4636bcb247ff2a 139 Pfam PF01957 NfeD-like C-terminal, partner-binding 8 138 7.1E-15 T 30-10-2018 IPR002810 NfeD-like, C-terminal domain CL1_1714 eb7dfef83aa23786af4636bcb247ff2a 139 SUPERFAMILY SSF141322 72 139 2.88E-16 T 30-10-2018 CL1_1714 eb7dfef83aa23786af4636bcb247ff2a 139 Gene3D G3DSA:2.40.50.140 69 139 2.4E-18 T 30-10-2018 CL1_1482 b8711b0a813044b4765909f44b68e1ee 293 Gene3D G3DSA:3.40.1190.20 13 287 2.2E-86 T 30-10-2018 IPR029056 Ribokinase-like CL1_1482 b8711b0a813044b4765909f44b68e1ee 293 Pfam PF00294 pfkB family carbohydrate kinase 193 267 5.4E-5 T 30-10-2018 IPR011611 Carbohydrate kinase PfkB CL1_1482 b8711b0a813044b4765909f44b68e1ee 293 SUPERFAMILY SSF53613 11 274 1.42E-35 T 30-10-2018 IPR029056 Ribokinase-like CL1_1801 0ea93452762e397a42b893b8d5d67b0b 95 SUPERFAMILY SSF117916 4 78 1.73E-7 T 30-10-2018 IPR034904 Fe-S cluster assembly domain superfamily CL1_1801 0ea93452762e397a42b893b8d5d67b0b 95 Gene3D G3DSA:3.30.300.130 2 85 4.4E-6 T 30-10-2018 IPR034904 Fe-S cluster assembly domain superfamily CL1_1012 eaa929405a3402aa4858b8b418e9381d 497 PIRSF PIRSF006615 5 497 6.0E-197 T 30-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 CL1_1012 eaa929405a3402aa4858b8b418e9381d 497 Pfam PF02074 Carboxypeptidase Taq (M32) metallopeptidase 11 496 8.9E-102 T 30-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 CL1_1012 eaa929405a3402aa4858b8b418e9381d 497 Gene3D G3DSA:1.10.1370.30 1 497 1.7E-194 T 30-10-2018 CL1_1012 eaa929405a3402aa4858b8b418e9381d 497 SUPERFAMILY SSF55486 7 497 2.56E-110 T 30-10-2018 CL1_1012 eaa929405a3402aa4858b8b418e9381d 497 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 231 247 2.2E-86 T 30-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 CL1_1012 eaa929405a3402aa4858b8b418e9381d 497 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 295 311 2.2E-86 T 30-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 CL1_1012 eaa929405a3402aa4858b8b418e9381d 497 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 404 425 2.2E-86 T 30-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 CL1_1012 eaa929405a3402aa4858b8b418e9381d 497 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 268 287 2.2E-86 T 30-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 CL1_1012 eaa929405a3402aa4858b8b418e9381d 497 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 448 466 2.2E-86 T 30-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 CL1_1012 eaa929405a3402aa4858b8b418e9381d 497 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 248 267 2.2E-86 T 30-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 CL1_1012 eaa929405a3402aa4858b8b418e9381d 497 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 335 354 2.2E-86 T 30-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 CL1_1012 eaa929405a3402aa4858b8b418e9381d 497 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 149 169 2.2E-86 T 30-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 CL1_1012 eaa929405a3402aa4858b8b418e9381d 497 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 381 398 2.2E-86 T 30-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 CL1_0724 d60bc186ccc23555a3ce00a923b063fc 125 Pfam PF01092 Ribosomal protein S6e 4 124 1.5E-37 T 30-10-2018 IPR001377 Ribosomal protein S6e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-166208|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0724 d60bc186ccc23555a3ce00a923b063fc 125 ProSitePatterns PS00578 Ribosomal protein S6e signature. 63 74 - T 30-10-2018 IPR018282 Ribosomal protein S6e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-166208|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0724 d60bc186ccc23555a3ce00a923b063fc 125 SMART SM01405 4 124 3.0E-52 T 30-10-2018 IPR001377 Ribosomal protein S6e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-166208|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0724 d60bc186ccc23555a3ce00a923b063fc 125 Hamap MF_00512 30S ribosomal protein S6e [rps6e]. 2 125 18.904 T 30-10-2018 IPR020924 Ribosomal protein S6e, archaeal GO:0003735|GO:0005840|GO:0006412 CL1_1789 025dae705395ddb9a0095b349cc6f379 136 Gene3D G3DSA:3.30.420.130 2 127 5.9E-15 T 30-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily CL1_1789 025dae705395ddb9a0095b349cc6f379 136 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 13 114 8.1E-16 T 30-10-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis CL1_1789 025dae705395ddb9a0095b349cc6f379 136 SUPERFAMILY SSF53146 3 117 1.15E-14 T 30-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily CL1_2029 23e26e7702938910bc4e8822e20251da 421 Pfam PF13635 Domain of unknown function (DUF4143) 249 358 5.9E-11 T 30-10-2018 IPR025420 Domain of unknown function DUF4143 CL1_2029 23e26e7702938910bc4e8822e20251da 421 SUPERFAMILY SSF52540 26 166 1.81E-19 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_2029 23e26e7702938910bc4e8822e20251da 421 Pfam PF13173 AAA domain 34 163 1.1E-33 T 30-10-2018 CL1_1261 e6590d819ea1cfec51d0b385acd9fde8 307 Gene3D G3DSA:3.40.50.720 10 301 3.8E-136 T 30-10-2018 CL1_1261 e6590d819ea1cfec51d0b385acd9fde8 307 SUPERFAMILY SSF51735 100 284 2.26E-67 T 30-10-2018 IPR036291 NAD(P)-binding domain superfamily CL1_1261 e6590d819ea1cfec51d0b385acd9fde8 307 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 193 215 - T 30-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CL1_1261 e6590d819ea1cfec51d0b385acd9fde8 307 Gene3D G3DSA:3.40.50.720 95 285 3.8E-136 T 30-10-2018 CL1_1261 e6590d819ea1cfec51d0b385acd9fde8 307 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 6 307 3.8E-41 T 30-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 CL1_1261 e6590d819ea1cfec51d0b385acd9fde8 307 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 222 238 - T 30-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CL1_1261 e6590d819ea1cfec51d0b385acd9fde8 307 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 108 283 1.2E-72 T 30-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CL1_1261 e6590d819ea1cfec51d0b385acd9fde8 307 SUPERFAMILY SSF52283 3 136 5.29E-40 T 30-10-2018 CL1_1261 e6590d819ea1cfec51d0b385acd9fde8 307 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 145 172 - T 30-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 CL1_0129 2d38bb6086e7906feff216fbc6f2ea91 212 Pfam PF01982 Domain of unknown function DUF120 92 209 7.7E-37 T 30-10-2018 IPR023602 Riboflavin kinase domain, CTP-dependent GO:0016773 KEGG: 00740+2.7.1.161|MetaCyc: PWY-6167 CL1_0129 2d38bb6086e7906feff216fbc6f2ea91 212 Hamap MF_01285 Riboflavin kinase [ribK]. 86 209 25.263 T 30-10-2018 IPR023470 Riboflavin kinase, archaeal GO:0008531|GO:0009231 KEGG: 00740+2.7.1.161|MetaCyc: PWY-6167 CL1_0129 2d38bb6086e7906feff216fbc6f2ea91 212 Gene3D G3DSA:1.10.10.10 1 83 9.2E-18 T 30-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CL1_0129 2d38bb6086e7906feff216fbc6f2ea91 212 Pfam PF13545 Crp-like helix-turn-helix domain 5 57 4.8E-9 T 30-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CL1_0129 2d38bb6086e7906feff216fbc6f2ea91 212 SUPERFAMILY SSF46785 4 79 3.54E-14 T 30-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CL1_0129 2d38bb6086e7906feff216fbc6f2ea91 212 Gene3D G3DSA:2.40.30.30 85 211 1.5E-39 T 30-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 CL1_0129 2d38bb6086e7906feff216fbc6f2ea91 212 SUPERFAMILY SSF82114 87 209 3.92E-39 T 30-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 CL1_0129 2d38bb6086e7906feff216fbc6f2ea91 212 SMART SM00347 1 101 0.0092 T 30-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CL1_1981 cd4dcc0310577de302e57e13156072d2 309 SMART SM00382 30 213 1.7E-10 T 30-10-2018 IPR003593 AAA+ ATPase domain CL1_1981 cd4dcc0310577de302e57e13156072d2 309 SUPERFAMILY SSF52540 6 227 4.78E-62 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_1981 cd4dcc0310577de302e57e13156072d2 309 Gene3D G3DSA:3.40.50.300 2 240 9.2E-68 T 30-10-2018 CL1_1981 cd4dcc0310577de302e57e13156072d2 309 Pfam PF00005 ABC transporter 22 165 2.9E-30 T 30-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CL1_1981 cd4dcc0310577de302e57e13156072d2 309 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 30-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CL1_1981 cd4dcc0310577de302e57e13156072d2 309 Pfam PF13732 Domain of unknown function (DUF4162) 218 302 4.2E-8 T 30-10-2018 IPR025302 Domain of unknown function DUF4162 CL1_0278 0de21a332f1954bb68af77b5282134f4 581 Gene3D G3DSA:1.10.150.320 519 579 2.9E-7 T 30-10-2018 CL1_0278 0de21a332f1954bb68af77b5282134f4 581 SMART SM00729 200 447 2.3E-31 T 30-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 CL1_0278 0de21a332f1954bb68af77b5282134f4 581 SUPERFAMILY SSF102114 197 438 3.79E-26 T 30-10-2018 CL1_0278 0de21a332f1954bb68af77b5282134f4 581 Pfam PF04055 Radical SAM superfamily 204 403 5.5E-24 T 30-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CL1_0278 0de21a332f1954bb68af77b5282134f4 581 SUPERFAMILY SSF81585 511 573 1.77E-9 T 30-10-2018 CL1_0278 0de21a332f1954bb68af77b5282134f4 581 Gene3D G3DSA:3.80.30.20 200 456 1.3E-24 T 30-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe CL1_0278 0de21a332f1954bb68af77b5282134f4 581 Pfam PF12836 Helix-hairpin-helix motif 526 566 4.1E-7 T 30-10-2018 CL1_0742 c178199a5bfc2075e955dd9cb43057f9 264 Pfam PF13649 Methyltransferase domain 43 142 6.7E-8 T 30-10-2018 CL1_0742 c178199a5bfc2075e955dd9cb43057f9 264 Gene3D G3DSA:3.40.50.150 7 173 6.8E-14 T 30-10-2018 CL1_0742 c178199a5bfc2075e955dd9cb43057f9 264 SUPERFAMILY SSF53335 32 173 2.05E-16 T 30-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CL1_1903 151d8dd7c27f539cca5158c545c95aac 230 SUPERFAMILY SSF53335 2 194 1.67E-51 T 30-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CL1_1903 151d8dd7c27f539cca5158c545c95aac 230 Pfam PF08241 Methyltransferase domain 43 132 6.4E-28 T 30-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 CL1_1903 151d8dd7c27f539cca5158c545c95aac 230 Gene3D G3DSA:3.40.50.150 1 189 5.0E-54 T 30-10-2018 CL1_1416 eace636e7bd0ef0067e1b27bd3e296d0 459 Gene3D G3DSA:3.40.50.261 130 289 1.7E-61 T 30-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CL1_1416 eace636e7bd0ef0067e1b27bd3e296d0 459 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 150 287 5.3E-56 T 30-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain CL1_1416 eace636e7bd0ef0067e1b27bd3e296d0 459 SUPERFAMILY SSF52210 292 451 4.84E-41 T 30-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CL1_1416 eace636e7bd0ef0067e1b27bd3e296d0 459 SUPERFAMILY SSF52210 132 288 2.62E-45 T 30-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CL1_1416 eace636e7bd0ef0067e1b27bd3e296d0 459 SUPERFAMILY SSF51735 3 138 1.85E-38 T 30-10-2018 IPR036291 NAD(P)-binding domain superfamily CL1_1416 eace636e7bd0ef0067e1b27bd3e296d0 459 Pfam PF13380 CoA binding domain 10 135 3.6E-26 T 30-10-2018 IPR003781 CoA-binding GO:0048037 CL1_1416 eace636e7bd0ef0067e1b27bd3e296d0 459 Gene3D G3DSA:3.40.50.720 3 129 4.1E-46 T 30-10-2018 CL1_1416 eace636e7bd0ef0067e1b27bd3e296d0 459 Gene3D G3DSA:3.40.50.261 290 458 1.4E-65 T 30-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CL1_1416 eace636e7bd0ef0067e1b27bd3e296d0 459 SMART SM00881 6 100 1.5E-34 T 30-10-2018 IPR003781 CoA-binding GO:0048037 CL1_0414 612a06584e8d1412534d842db24e2149 361 Pfam PF00483 Nucleotidyl transferase 2 231 8.6E-52 T 30-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 CL1_0414 612a06584e8d1412534d842db24e2149 361 Gene3D G3DSA:3.90.550.10 1 242 6.7E-77 T 30-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases CL1_0414 612a06584e8d1412534d842db24e2149 361 SUPERFAMILY SSF53448 1 314 7.15E-80 T 30-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases CL1_0414 612a06584e8d1412534d842db24e2149 361 SUPERFAMILY SSF51161 200 355 1.39E-25 T 30-10-2018 IPR011004 Trimeric LpxA-like superfamily CL1_0414 612a06584e8d1412534d842db24e2149 361 Gene3D G3DSA:2.160.10.10 267 361 8.6E-19 T 30-10-2018 CL1_0414 612a06584e8d1412534d842db24e2149 361 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 258 293 9.4E-7 T 30-10-2018 IPR001451 Hexapeptide repeat CL1_0414 612a06584e8d1412534d842db24e2149 361 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 296 329 1.9E-6 T 30-10-2018 IPR001451 Hexapeptide repeat CL1_1197 803ee0896abadcd19854a017ca2955c0 559 SUPERFAMILY SSF117018 2 242 4.84E-71 T 30-10-2018 IPR036599 DNA ligase, ATP-dependent, N-terminal domain superfamily GO:0003677|GO:0003910|GO:0006281|GO:0006310 CL1_1197 803ee0896abadcd19854a017ca2955c0 559 Pfam PF04679 ATP dependent DNA ligase C terminal region 443 534 2.1E-20 T 30-10-2018 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 CL1_1197 803ee0896abadcd19854a017ca2955c0 559 TIGRFAM TIGR00574 dnl1: DNA ligase I, ATP-dependent (dnl1) 57 550 2.8E-165 T 30-10-2018 IPR000977 DNA ligase, ATP-dependent GO:0003910|GO:0005524|GO:0006281|GO:0006310|GO:0071897 CL1_1197 803ee0896abadcd19854a017ca2955c0 559 SUPERFAMILY SSF50249 425 552 3.37E-40 T 30-10-2018 IPR012340 Nucleic acid-binding, OB-fold CL1_1197 803ee0896abadcd19854a017ca2955c0 559 Pfam PF01068 ATP dependent DNA ligase domain 224 422 8.5E-66 T 30-10-2018 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 CL1_1197 803ee0896abadcd19854a017ca2955c0 559 Hamap MF_00407 DNA ligase [lig]. 1 550 34.828 T 30-10-2018 IPR022865 DNA ligase, ATP-dependent, bacterial/archaeal GO:0003910 CL1_1197 803ee0896abadcd19854a017ca2955c0 559 ProSitePatterns PS00697 ATP-dependent DNA ligase AMP-binding site. 247 255 - T 30-10-2018 IPR016059 DNA ligase, ATP-dependent, conserved site GO:0003909|GO:0051103 CL1_1197 803ee0896abadcd19854a017ca2955c0 559 Pfam PF04675 DNA ligase N terminus 3 176 1.6E-38 T 30-10-2018 IPR012308 DNA ligase, ATP-dependent, N-terminal GO:0003677|GO:0003910|GO:0006281|GO:0006310 CL1_1197 803ee0896abadcd19854a017ca2955c0 559 Gene3D G3DSA:2.40.50.140 423 559 4.7E-52 T 30-10-2018 CL1_1197 803ee0896abadcd19854a017ca2955c0 559 SUPERFAMILY SSF56091 219 422 1.87E-56 T 30-10-2018 CL1_1197 803ee0896abadcd19854a017ca2955c0 559 Gene3D G3DSA:3.30.470.30 221 422 7.7E-75 T 30-10-2018 CL1_1197 803ee0896abadcd19854a017ca2955c0 559 Gene3D G3DSA:1.10.3260.10 1 220 6.6E-85 T 30-10-2018 IPR036599 DNA ligase, ATP-dependent, N-terminal domain superfamily GO:0003677|GO:0003910|GO:0006281|GO:0006310 CL1_1197 803ee0896abadcd19854a017ca2955c0 559 ProSitePatterns PS00333 ATP-dependent DNA ligase signature 2. 398 422 - T 30-10-2018 IPR016059 DNA ligase, ATP-dependent, conserved site GO:0003909|GO:0051103 CL1_1975 3457e0eba215c4e14284ecb2f63c6bc8 142 Hamap MF_01222 Protein archease. 2 142 40.756 T 30-10-2018 IPR022952 Archease, archaea CL1_1975 3457e0eba215c4e14284ecb2f63c6bc8 142 ProDom PD012969 UPF0211 RIKEN CDNA ENRICHED MALE FULL-LENGTH LIBRARY ZBTB8OS ADULT C43H8.1 8 142 9.0E-44 T 30-10-2018 IPR023572 Archease domain Reactome: R-HSA-6784531 CL1_1975 3457e0eba215c4e14284ecb2f63c6bc8 142 Gene3D G3DSA:3.55.10.10 1 142 5.4E-51 T 30-10-2018 IPR036820 Archease domain superfamily Reactome: R-HSA-6784531 CL1_1975 3457e0eba215c4e14284ecb2f63c6bc8 142 Pfam PF01951 Archease protein family (MTH1598/TM1083) 4 141 1.6E-44 T 30-10-2018 IPR023572 Archease domain Reactome: R-HSA-6784531 CL1_1975 3457e0eba215c4e14284ecb2f63c6bc8 142 SUPERFAMILY SSF69819 2 142 3.01E-47 T 30-10-2018 IPR036820 Archease domain superfamily Reactome: R-HSA-6784531 CL1_0326 0506bc30efaa74e52af37c9a9b519c40 333 Gene3D G3DSA:3.40.1750.20 187 253 3.6E-53 T 30-10-2018 CL1_0326 0506bc30efaa74e52af37c9a9b519c40 333 Pfam PF01343 Peptidase family S49 149 296 6.8E-39 T 30-10-2018 IPR002142 Peptidase S49 GO:0006508|GO:0008233 CL1_0326 0506bc30efaa74e52af37c9a9b519c40 333 TIGRFAM TIGR00706 SppA_dom: signal peptide peptidase SppA, 36K type 89 292 2.1E-66 T 30-10-2018 IPR004635 Peptidase S49, SppA GO:0006508|GO:0008233 CL1_0326 0506bc30efaa74e52af37c9a9b519c40 333 Gene3D G3DSA:3.90.226.10 91 288 3.6E-53 T 30-10-2018 CL1_0326 0506bc30efaa74e52af37c9a9b519c40 333 SUPERFAMILY SSF52096 80 281 1.24E-37 T 30-10-2018 IPR029045 ClpP/crotonase-like domain superfamily CL1_1827 9b7eae13813d7bb3cf069458b737c210 377 Gene3D G3DSA:3.40.50.1980 2 213 2.7E-68 T 30-10-2018 CL1_1827 9b7eae13813d7bb3cf069458b737c210 377 SUPERFAMILY SSF53720 8 376 3.14E-54 T 30-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 CL1_1827 9b7eae13813d7bb3cf069458b737c210 377 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 9 250 7.6E-91 T 30-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CL1_1827 9b7eae13813d7bb3cf069458b737c210 377 ProSitePatterns PS00611 Histidinol dehydrogenase signature. 199 231 - T 30-10-2018 IPR001692 Histidinol dehydrogenase, conserved site GO:0000105|GO:0004399|GO:0055114 KEGG: 00340+1.1.1.23 CL1_1827 9b7eae13813d7bb3cf069458b737c210 377 Gene3D G3DSA:3.40.50.1980 249 321 2.7E-20 T 30-10-2018 CL1_1827 9b7eae13813d7bb3cf069458b737c210 377 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 1 377 36.156 T 30-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CL1_1827 9b7eae13813d7bb3cf069458b737c210 377 PRINTS PR00083 Histidinol dehydrogenase signature 311 329 1.1E-94 T 30-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CL1_1827 9b7eae13813d7bb3cf069458b737c210 377 PRINTS PR00083 Histidinol dehydrogenase signature 80 107 1.1E-94 T 30-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CL1_1827 9b7eae13813d7bb3cf069458b737c210 377 PRINTS PR00083 Histidinol dehydrogenase signature 199 220 1.1E-94 T 30-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CL1_1827 9b7eae13813d7bb3cf069458b737c210 377 PRINTS PR00083 Histidinol dehydrogenase signature 270 295 1.1E-94 T 30-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CL1_1827 9b7eae13813d7bb3cf069458b737c210 377 PRINTS PR00083 Histidinol dehydrogenase signature 170 195 1.1E-94 T 30-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CL1_1827 9b7eae13813d7bb3cf069458b737c210 377 PRINTS PR00083 Histidinol dehydrogenase signature 107 133 1.1E-94 T 30-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CL1_1827 9b7eae13813d7bb3cf069458b737c210 377 PRINTS PR00083 Histidinol dehydrogenase signature 9 33 1.1E-94 T 30-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CL1_1827 9b7eae13813d7bb3cf069458b737c210 377 PRINTS PR00083 Histidinol dehydrogenase signature 141 167 1.1E-94 T 30-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CL1_1827 9b7eae13813d7bb3cf069458b737c210 377 PRINTS PR00083 Histidinol dehydrogenase signature 221 240 1.1E-94 T 30-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CL1_1827 9b7eae13813d7bb3cf069458b737c210 377 Pfam PF00815 Histidinol dehydrogenase 5 250 8.1E-90 T 30-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CL1_1827 9b7eae13813d7bb3cf069458b737c210 377 Pfam PF00815 Histidinol dehydrogenase 255 376 3.9E-38 T 30-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CL1_1594 f90306dd766ba83add566722ea1d0a76 418 Gene3D G3DSA:3.40.50.300 20 81 3.3E-6 T 30-10-2018 CL1_1594 f90306dd766ba83add566722ea1d0a76 418 SMART SM00382 33 158 0.0026 T 30-10-2018 IPR003593 AAA+ ATPase domain CL1_1594 f90306dd766ba83add566722ea1d0a76 418 Pfam PF13635 Domain of unknown function (DUF4143) 220 355 2.0E-7 T 30-10-2018 IPR025420 Domain of unknown function DUF4143 CL1_1594 f90306dd766ba83add566722ea1d0a76 418 SUPERFAMILY SSF52540 28 224 1.0E-24 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_1594 f90306dd766ba83add566722ea1d0a76 418 Pfam PF13173 AAA domain 35 164 3.2E-36 T 30-10-2018 CL1_0933 c50347f0fc9e0358e7c8981e52a3e7ff 203 SUPERFAMILY SSF81573 23 82 6.34E-6 T 30-10-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain superfamily CL1_0933 c50347f0fc9e0358e7c8981e52a3e7ff 203 SUPERFAMILY SSF160527 81 203 4.45E-26 T 30-10-2018 CL1_0933 c50347f0fc9e0358e7c8981e52a3e7ff 203 Gene3D G3DSA:3.30.2320.30 100 203 5.2E-19 T 30-10-2018 IPR038495 V-type ATPase subunit E, C-terminal domain superfamily Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 CL1_0933 c50347f0fc9e0358e7c8981e52a3e7ff 203 Pfam PF01991 ATP synthase (E/31 kDa) subunit 10 202 6.5E-39 T 30-10-2018 IPR002842 V-type ATPase subunit E GO:0015991|GO:0033178|GO:0046961 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 CL1_0933 c50347f0fc9e0358e7c8981e52a3e7ff 203 Hamap MF_00311 V-type proton ATPase subunit E [atpE]. 2 203 15.371 T 30-10-2018 IPR002842 V-type ATPase subunit E GO:0015991|GO:0033178|GO:0046961 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 CL1_0933 c50347f0fc9e0358e7c8981e52a3e7ff 203 Gene3D G3DSA:1.20.5.620 18 98 4.0E-25 T 30-10-2018 CL1_1440 9438d2cba11672156cc2436b06ab7674 288 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 222 257 6.8E-12 T 30-10-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain CL1_1440 9438d2cba11672156cc2436b06ab7674 288 Gene3D G3DSA:3.40.50.80 101 212 4.5E-26 T 30-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain CL1_1440 9438d2cba11672156cc2436b06ab7674 288 SUPERFAMILY SSF63380 2 94 3.14E-15 T 30-10-2018 IPR017938 Riboflavin synthase-like beta-barrel CL1_1440 9438d2cba11672156cc2436b06ab7674 288 PIRSF PIRSF006816 1 264 3.3E-66 T 30-10-2018 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 CL1_1440 9438d2cba11672156cc2436b06ab7674 288 Gene3D G3DSA:2.40.30.10 2 93 4.3E-16 T 30-10-2018 CL1_1440 9438d2cba11672156cc2436b06ab7674 288 SUPERFAMILY SSF52343 90 257 2.4E-16 T 30-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain CL1_1381 1be3b58501313770f6d0333507d09ba4 501 Gene3D G3DSA:3.50.50.60 222 312 6.6E-145 T 30-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily CL1_1381 1be3b58501313770f6d0333507d09ba4 501 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 268 355 8.9E-8 T 30-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CL1_1381 1be3b58501313770f6d0333507d09ba4 501 Gene3D G3DSA:1.10.10.1100 401 477 6.6E-145 T 30-10-2018 CL1_1381 1be3b58501313770f6d0333507d09ba4 501 Gene3D G3DSA:3.10.20.440 1 95 4.7E-40 T 30-10-2018 CL1_1381 1be3b58501313770f6d0333507d09ba4 501 SUPERFAMILY SSF51905 110 372 9.39E-21 T 30-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily CL1_1381 1be3b58501313770f6d0333507d09ba4 501 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 13 87 3.7E-15 T 30-10-2018 CL1_1381 1be3b58501313770f6d0333507d09ba4 501 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 110 260 6.7E-11 T 30-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CL1_1381 1be3b58501313770f6d0333507d09ba4 501 Gene3D G3DSA:3.50.50.60 110 483 6.6E-145 T 30-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily CL1_1381 1be3b58501313770f6d0333507d09ba4 501 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 304 320 3.8E-7 T 30-10-2018 CL1_1381 1be3b58501313770f6d0333507d09ba4 501 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 210 228 3.8E-7 T 30-10-2018 CL1_1381 1be3b58501313770f6d0333507d09ba4 501 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 111 130 3.8E-7 T 30-10-2018 CL1_0611 6e31f0d4b7a2646f7b3920a8b89d8b35 184 Pfam PF00347 Ribosomal protein L6 13 85 1.1E-17 T 30-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0611 6e31f0d4b7a2646f7b3920a8b89d8b35 184 Pfam PF00347 Ribosomal protein L6 97 171 3.8E-16 T 30-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0611 6e31f0d4b7a2646f7b3920a8b89d8b35 184 PIRSF PIRSF002162 5 182 2.8E-40 T 30-10-2018 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0611 6e31f0d4b7a2646f7b3920a8b89d8b35 184 SUPERFAMILY SSF56053 86 177 2.09E-31 T 30-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0611 6e31f0d4b7a2646f7b3920a8b89d8b35 184 Gene3D G3DSA:3.90.930.12 6 85 2.0E-30 T 30-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0611 6e31f0d4b7a2646f7b3920a8b89d8b35 184 Hamap MF_01365_A 50S ribosomal protein L6 [rplF]. 2 178 39.61 T 30-10-2018 IPR019907 Ribosomal protein L6P, archaea GO:0003735|GO:0005840|GO:0006412|GO:0019843 CL1_0611 6e31f0d4b7a2646f7b3920a8b89d8b35 184 TIGRFAM TIGR03653 uL6_arch: ribosomal protein uL6 8 177 1.0E-79 T 30-10-2018 IPR019907 Ribosomal protein L6P, archaea GO:0003735|GO:0005840|GO:0006412|GO:0019843 CL1_0611 6e31f0d4b7a2646f7b3920a8b89d8b35 184 Gene3D G3DSA:3.90.930.12 86 182 9.6E-39 T 30-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0611 6e31f0d4b7a2646f7b3920a8b89d8b35 184 ProSitePatterns PS00700 Ribosomal protein L6 signature 2. 156 177 - T 30-10-2018 IPR002359 Ribosomal protein L6, conserved site-2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0611 6e31f0d4b7a2646f7b3920a8b89d8b35 184 SUPERFAMILY SSF56053 8 85 5.55E-22 T 30-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0795 d89fcffaa9501f7af06025f9e9451db8 197 PIRSF PIRSF005639 1 197 6.1E-68 T 30-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CL1_0795 d89fcffaa9501f7af06025f9e9451db8 197 TIGRFAM TIGR03800 PLP_synth_Pdx2: pyridoxal 5'-phosphate synthase, glutaminase subunit Pdx2 3 193 1.6E-74 T 30-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CL1_0795 d89fcffaa9501f7af06025f9e9451db8 197 ProSitePatterns PS01236 PdxT/SNO family family signature. 47 57 - T 30-10-2018 IPR021196 PdxT/SNO family, conserved site KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CL1_0795 d89fcffaa9501f7af06025f9e9451db8 197 Gene3D G3DSA:3.40.50.880 1 197 1.9E-67 T 30-10-2018 IPR029062 Class I glutamine amidotransferase-like CL1_0795 d89fcffaa9501f7af06025f9e9451db8 197 Hamap MF_01615 Pyridoxal 5'-phosphate synthase subunit PdxT [pdxT]. 4 195 35.345 T 30-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CL1_0795 d89fcffaa9501f7af06025f9e9451db8 197 Pfam PF01174 SNO glutamine amidotransferase family 6 194 1.9E-54 T 30-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CL1_0795 d89fcffaa9501f7af06025f9e9451db8 197 SUPERFAMILY SSF52317 2 194 1.63E-47 T 30-10-2018 IPR029062 Class I glutamine amidotransferase-like CL1_0748 fea55a2954a48026557485f823619613 352 Gene3D G3DSA:3.90.550.10 1 240 1.1E-53 T 30-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases CL1_0748 fea55a2954a48026557485f823619613 352 Pfam PF00535 Glycosyl transferase family 2 4 168 9.2E-39 T 30-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CL1_0748 fea55a2954a48026557485f823619613 352 SUPERFAMILY SSF53448 2 226 1.24E-45 T 30-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases CL1_0748 fea55a2954a48026557485f823619613 352 Pfam PF04138 GtrA-like protein 236 351 1.2E-27 T 30-10-2018 IPR007267 GtrA-like protein GO:0000271|GO:0016021 CL1_1564 2f21373fdc5b6eaf27970d8a69bec152 129 Pfam PF14464 Prokaryotic homologs of the JAB domain 15 107 1.1E-15 T 30-10-2018 IPR028090 JAB domain, prokaryotic CL1_1564 2f21373fdc5b6eaf27970d8a69bec152 129 SMART SM00232 2 126 1.7E-5 T 30-10-2018 IPR000555 JAB1/MPN/MOV34 metalloenzyme domain GO:0005515 CL1_1564 2f21373fdc5b6eaf27970d8a69bec152 129 Gene3D G3DSA:3.40.140.10 3 129 7.8E-27 T 30-10-2018 CL1_1564 2f21373fdc5b6eaf27970d8a69bec152 129 SUPERFAMILY SSF102712 3 124 2.09E-20 T 30-10-2018 CL1_0110 d5be28906b7d2f28e06ef92a9e2619e7 735 Gene3D G3DSA:2.170.220.10 98 251 6.5E-144 T 30-10-2018 CL1_0110 d5be28906b7d2f28e06ef92a9e2619e7 735 Gene3D G3DSA:1.10.730.10 397 547 2.3E-105 T 30-10-2018 CL1_0110 d5be28906b7d2f28e06ef92a9e2619e7 735 TIGRFAM TIGR00399 metG_C_term: methionine--tRNA ligase, beta subunit 610 735 2.4E-38 T 30-10-2018 IPR004495 Methionyl-tRNA synthetase, beta subunit, C-terminal GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CL1_0110 d5be28906b7d2f28e06ef92a9e2619e7 735 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 5 548 4.9E-177 T 30-10-2018 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CL1_0110 d5be28906b7d2f28e06ef92a9e2619e7 735 SUPERFAMILY SSF52374 3 394 9.19E-107 T 30-10-2018 CL1_0110 d5be28906b7d2f28e06ef92a9e2619e7 735 Pfam PF08264 Anticodon-binding domain of tRNA 429 522 1.4E-12 T 30-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 CL1_0110 d5be28906b7d2f28e06ef92a9e2619e7 735 Gene3D G3DSA:2.40.50.140 629 735 8.5E-44 T 30-10-2018 CL1_0110 d5be28906b7d2f28e06ef92a9e2619e7 735 Hamap MF_00098 Methionine--tRNA ligase [metG]. 2 559 42.959 T 30-10-2018 IPR023458 Methionine-tRNA ligase, type 1 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CL1_0110 d5be28906b7d2f28e06ef92a9e2619e7 735 Pfam PF01588 Putative tRNA binding domain 641 732 6.2E-32 T 30-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 CL1_0110 d5be28906b7d2f28e06ef92a9e2619e7 735 Pfam PF09334 tRNA synthetases class I (M) 4 407 1.7E-159 T 30-10-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 CL1_0110 d5be28906b7d2f28e06ef92a9e2619e7 735 SUPERFAMILY SSF57770 139 173 1.03E-10 T 30-10-2018 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CL1_0110 d5be28906b7d2f28e06ef92a9e2619e7 735 Gene3D G3DSA:3.40.50.620 5 315 6.5E-144 T 30-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CL1_0110 d5be28906b7d2f28e06ef92a9e2619e7 735 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 11 22 - T 30-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CL1_0110 d5be28906b7d2f28e06ef92a9e2619e7 735 SUPERFAMILY SSF50249 634 734 1.08E-36 T 30-10-2018 IPR012340 Nucleic acid-binding, OB-fold CL1_0110 d5be28906b7d2f28e06ef92a9e2619e7 735 PRINTS PR01041 Methionyl-tRNA synthetase signature 6 19 5.2E-33 T 30-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CL1_0110 d5be28906b7d2f28e06ef92a9e2619e7 735 PRINTS PR01041 Methionyl-tRNA synthetase signature 251 262 5.2E-33 T 30-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CL1_0110 d5be28906b7d2f28e06ef92a9e2619e7 735 PRINTS PR01041 Methionyl-tRNA synthetase signature 293 308 5.2E-33 T 30-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CL1_0110 d5be28906b7d2f28e06ef92a9e2619e7 735 PRINTS PR01041 Methionyl-tRNA synthetase signature 87 98 5.2E-33 T 30-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CL1_0110 d5be28906b7d2f28e06ef92a9e2619e7 735 PRINTS PR01041 Methionyl-tRNA synthetase signature 395 406 5.2E-33 T 30-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CL1_0110 d5be28906b7d2f28e06ef92a9e2619e7 735 PRINTS PR01041 Methionyl-tRNA synthetase signature 39 53 5.2E-33 T 30-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CL1_0110 d5be28906b7d2f28e06ef92a9e2619e7 735 Gene3D G3DSA:1.10.730.10 340 580 2.3E-105 T 30-10-2018 CL1_0110 d5be28906b7d2f28e06ef92a9e2619e7 735 SUPERFAMILY SSF47323 397 584 2.43E-45 T 30-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CL1_1146 3b79779d5d571b8a4ea62d76238bb171 123 Pfam PF12838 4Fe-4S dicluster domain 9 57 6.4E-10 T 30-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CL1_1146 3b79779d5d571b8a4ea62d76238bb171 123 SUPERFAMILY SSF54862 2 62 2.85E-17 T 30-10-2018 CL1_1146 3b79779d5d571b8a4ea62d76238bb171 123 Gene3D G3DSA:3.30.70.20 1 61 9.4E-13 T 30-10-2018 CL1_0296 bcfb6105faeaae358f006aecbe4556be 286 SMART SM00382 30 227 3.8E-15 T 30-10-2018 IPR003593 AAA+ ATPase domain CL1_0296 bcfb6105faeaae358f006aecbe4556be 286 Gene3D G3DSA:3.40.50.300 2 272 3.8E-71 T 30-10-2018 CL1_0296 bcfb6105faeaae358f006aecbe4556be 286 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 30-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CL1_0296 bcfb6105faeaae358f006aecbe4556be 286 Pfam PF00005 ABC transporter 21 178 6.2E-26 T 30-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CL1_0296 bcfb6105faeaae358f006aecbe4556be 286 SUPERFAMILY SSF52540 3 240 3.48E-59 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_1671 6bba30e99f9ebb46ce81456fd340c196 192 Pfam PF01895 PhoU domain 11 94 2.4E-8 T 30-10-2018 IPR026022 PhoU domain CL1_1671 6bba30e99f9ebb46ce81456fd340c196 192 Gene3D G3DSA:1.20.58.220 1 110 3.9E-19 T 30-10-2018 IPR038078 PhoU-like domain superfamily CL1_1671 6bba30e99f9ebb46ce81456fd340c196 192 SUPERFAMILY SSF116726 103 183 4.45E-18 T 30-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 CL1_1671 6bba30e99f9ebb46ce81456fd340c196 192 Pfam PF02080 TrkA-C domain 118 176 2.6E-14 T 30-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CL1_1671 6bba30e99f9ebb46ce81456fd340c196 192 SUPERFAMILY SSF109755 3 109 4.58E-15 T 30-10-2018 CL1_1671 6bba30e99f9ebb46ce81456fd340c196 192 Gene3D G3DSA:3.30.70.1450 111 190 1.5E-19 T 30-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 CL1_1586 315bcd985f9534b5f5411796be07d31a 149 Pfam PF06146 Phosphate-starvation-inducible E 58 123 1.5E-13 T 30-10-2018 IPR020948 Phosphate-starvation-induced PsiE-like CL1_0609 34457615d940c4eb9c40189b810fed46 148 Hamap MF_01475 50S ribosomal protein L19e [rpl19e]. 1 147 26.198 T 30-10-2018 IPR000196 Ribosomal protein L19/L19e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0609 34457615d940c4eb9c40189b810fed46 148 Gene3D G3DSA:1.10.1200.240 56 147 2.3E-30 T 30-10-2018 CL1_0609 34457615d940c4eb9c40189b810fed46 148 Gene3D G3DSA:1.10.1650.10 1 54 2.0E-25 T 30-10-2018 IPR015972 Ribosomal protein L19/L19e, domain 1 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0609 34457615d940c4eb9c40189b810fed46 148 SUPERFAMILY SSF48140 1 141 2.35E-57 T 30-10-2018 IPR035970 Ribosomal protein L19/L19e superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0609 34457615d940c4eb9c40189b810fed46 148 SMART SM01416 1 144 9.5E-89 T 30-10-2018 IPR000196 Ribosomal protein L19/L19e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0609 34457615d940c4eb9c40189b810fed46 148 ProSitePatterns PS00526 Ribosomal protein L19e signature. 5 24 - T 30-10-2018 IPR023638 Ribosomal protein L19/L19e conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0609 34457615d940c4eb9c40189b810fed46 148 Pfam PF01280 Ribosomal protein L19e 2 143 5.9E-59 T 30-10-2018 IPR000196 Ribosomal protein L19/L19e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0574 be651c5fcdfdb426d9e766db5a7b036f 433 Gene3D G3DSA:1.25.40.10 216 406 3.9E-11 T 30-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 CL1_0574 be651c5fcdfdb426d9e766db5a7b036f 433 Gene3D G3DSA:1.25.40.10 1 175 7.5E-14 T 30-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 CL1_1227 27cd58bf1bfe7460561c06d5548c81f2 398 PIRSF PIRSF006487 1 398 5.3E-105 T 30-10-2018 IPR028896 Aminomethyltransferase-like KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 CL1_1227 27cd58bf1bfe7460561c06d5548c81f2 398 SUPERFAMILY SSF103025 2 307 1.88E-94 T 30-10-2018 CL1_1227 27cd58bf1bfe7460561c06d5548c81f2 398 Gene3D G3DSA:2.40.30.110 309 383 1.0E-30 T 30-10-2018 CL1_1227 27cd58bf1bfe7460561c06d5548c81f2 398 Pfam PF01571 Aminomethyltransferase folate-binding domain 7 287 4.6E-97 T 30-10-2018 IPR006222 Aminomethyltransferase, folate-binding domain CL1_1227 27cd58bf1bfe7460561c06d5548c81f2 398 Hamap MF_00259 Aminomethyltransferase [gcvT]. 1 389 43.657 T 30-10-2018 IPR022903 Glycine cleavage system T protein, bacteria GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 CL1_1227 27cd58bf1bfe7460561c06d5548c81f2 398 Gene3D G3DSA:4.10.1250.10 268 305 1.7E-9 T 30-10-2018 CL1_1227 27cd58bf1bfe7460561c06d5548c81f2 398 SUPERFAMILY SSF101790 300 392 3.6E-25 T 30-10-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal CL1_1227 27cd58bf1bfe7460561c06d5548c81f2 398 Gene3D G3DSA:3.30.70.1400 52 143 7.7E-91 T 30-10-2018 CL1_1227 27cd58bf1bfe7460561c06d5548c81f2 398 TIGRFAM TIGR00528 gcvT: glycine cleavage system T protein 3 387 1.2E-97 T 30-10-2018 IPR006223 Glycine cleavage system T protein GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 CL1_1227 27cd58bf1bfe7460561c06d5548c81f2 398 Gene3D G3DSA:3.30.1360.120 8 255 7.7E-91 T 30-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 CL1_1227 27cd58bf1bfe7460561c06d5548c81f2 398 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 293 382 9.1E-26 T 30-10-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 CL1_1150 0ed983caa733aa7e7c8850d2463b50d2 226 Gene3D G3DSA:3.40.50.700 2 156 1.1E-39 T 30-10-2018 IPR037024 [NiFe]-hydrogenase, small subunit, N-terminal domain superfamily CL1_1150 0ed983caa733aa7e7c8850d2463b50d2 226 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 14 134 1.8E-23 T 30-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CL1_1150 0ed983caa733aa7e7c8850d2463b50d2 226 Gene3D G3DSA:3.30.70.20 158 220 1.5E-17 T 30-10-2018 CL1_1150 0ed983caa733aa7e7c8850d2463b50d2 226 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 202 213 - T 30-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CL1_1150 0ed983caa733aa7e7c8850d2463b50d2 226 SUPERFAMILY SSF56770 3 214 3.4E-36 T 30-10-2018 CL1_1150 0ed983caa733aa7e7c8850d2463b50d2 226 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 173 184 - T 30-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CL1_1150 0ed983caa733aa7e7c8850d2463b50d2 226 Pfam PF13187 4Fe-4S dicluster domain 173 215 1.1E-8 T 30-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CL1_1150 0ed983caa733aa7e7c8850d2463b50d2 226 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 118 141 3.4E-5 T 30-10-2018 CL1_1150 0ed983caa733aa7e7c8850d2463b50d2 226 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 69 83 3.4E-5 T 30-10-2018 CL1_1528 5651e3ca3f29b33a74608852e4340e70 209 TIGRFAM TIGR01491 HAD-SF-IB-PSPlk: phosphoserine phosphatase-like hydrolase, archaeal 2 183 2.6E-56 T 30-10-2018 IPR006386 HAD-superfamily hydrolase, subfamily IB, PSPase-like, archaeal CL1_1528 5651e3ca3f29b33a74608852e4340e70 209 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 4 173 5.1E-32 T 30-10-2018 CL1_1528 5651e3ca3f29b33a74608852e4340e70 209 Pfam PF12710 haloacid dehalogenase-like hydrolase 5 172 8.4E-21 T 30-10-2018 CL1_1528 5651e3ca3f29b33a74608852e4340e70 209 Gene3D G3DSA:1.10.150.210 14 75 6.4E-51 T 30-10-2018 IPR023190 Phosphoserine phosphatase, domain 2 GO:0004647|GO:0006564 KEGG: 00260+3.1.3.3|KEGG: 00680+3.1.3.3|Reactome: R-HSA-977347 CL1_1528 5651e3ca3f29b33a74608852e4340e70 209 SUPERFAMILY SSF56784 3 205 6.94E-42 T 30-10-2018 IPR036412 HAD-like superfamily CL1_1528 5651e3ca3f29b33a74608852e4340e70 209 Gene3D G3DSA:3.40.50.1000 3 187 6.4E-51 T 30-10-2018 IPR023214 HAD superfamily CL1_1772 e4ad1a246bf75ad74d2033c3c0e62eaf 356 Pfam PF01008 Initiation factor 2 subunit family 55 343 1.7E-82 T 30-10-2018 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 CL1_1772 e4ad1a246bf75ad74d2033c3c0e62eaf 356 Hamap MF_01678 Putative methylthioribose-1-phosphate isomerase [mtnA]. 13 353 40.04 T 30-10-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 CL1_1772 e4ad1a246bf75ad74d2033c3c0e62eaf 356 TIGRFAM TIGR00512 salvage_mtnA: S-methyl-5-thioribose-1-phosphate isomerase 15 342 1.6E-128 T 30-10-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 CL1_1772 e4ad1a246bf75ad74d2033c3c0e62eaf 356 TIGRFAM TIGR00524 eIF-2B_rel: eIF-2B alpha/beta/delta-related uncharacterized proteins 42 343 6.5E-114 T 30-10-2018 IPR011559 Initiation factor 2B alpha/beta/delta GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 CL1_1772 e4ad1a246bf75ad74d2033c3c0e62eaf 356 SUPERFAMILY SSF100950 12 351 2.23E-115 T 30-10-2018 IPR037171 NagB/RpiA transferase-like CL1_1772 e4ad1a246bf75ad74d2033c3c0e62eaf 356 Gene3D G3DSA:3.40.50.10470 159 356 2.5E-60 T 30-10-2018 CL1_1772 e4ad1a246bf75ad74d2033c3c0e62eaf 356 Gene3D G3DSA:1.20.120.420 11 156 7.4E-46 T 30-10-2018 IPR027363 Methylthioribose-1-phosphate isomerase, N-terminal KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 CL1_0374 2671a8873f92b76f46059e81979a52e0 232 Pfam PF13549 ATP-grasp domain 16 231 1.3E-83 T 30-10-2018 CL1_0374 2671a8873f92b76f46059e81979a52e0 232 Gene3D G3DSA:3.30.470.20 21 230 9.8E-91 T 30-10-2018 CL1_0374 2671a8873f92b76f46059e81979a52e0 232 SUPERFAMILY SSF56059 23 232 2.65E-51 T 30-10-2018 CL1_0374 2671a8873f92b76f46059e81979a52e0 232 Gene3D G3DSA:3.30.1490.20 39 116 9.8E-91 T 30-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 CL1_0922 a007774bafcf7ad6c8b4a80df94e8dd6 425 SUPERFAMILY SSF161098 211 407 8.11E-14 T 30-10-2018 IPR035906 MetI-like superfamily CL1_0922 a007774bafcf7ad6c8b4a80df94e8dd6 425 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 235 415 6.1E-13 T 30-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 CL1_0922 a007774bafcf7ad6c8b4a80df94e8dd6 425 Gene3D G3DSA:1.10.3720.10 210 421 2.0E-14 T 30-10-2018 IPR035906 MetI-like superfamily CL1_0821 e0e85c13e084f324b0c281c650b7ae34 91 Hamap MF_00043 Elongation factor 1-beta [ef1b]. 1 91 39.298 T 30-10-2018 IPR004542 Translation elongation factor EF1B, beta chain, archaeal GO:0003746|GO:0006414 CL1_0821 e0e85c13e084f324b0c281c650b7ae34 91 SUPERFAMILY SSF54984 9 91 1.12E-20 T 30-10-2018 IPR036219 Translation elongation factor eEF-1beta-like superfamily Reactome: R-HSA-156842 CL1_0821 e0e85c13e084f324b0c281c650b7ae34 91 Gene3D G3DSA:3.30.70.60 1 91 9.3E-35 T 30-10-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 CL1_0821 e0e85c13e084f324b0c281c650b7ae34 91 TIGRFAM TIGR00489 aEF-1_beta: translation elongation factor aEF-1 beta 7 90 3.1E-21 T 30-10-2018 IPR004542 Translation elongation factor EF1B, beta chain, archaeal GO:0003746|GO:0006414 CL1_0821 e0e85c13e084f324b0c281c650b7ae34 91 PIRSF PIRSF006521 3 91 2.5E-31 T 30-10-2018 IPR004542 Translation elongation factor EF1B, beta chain, archaeal GO:0003746|GO:0006414 CL1_0821 e0e85c13e084f324b0c281c650b7ae34 91 SMART SM00888 5 91 1.8E-30 T 30-10-2018 IPR014038 Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain GO:0003746|GO:0006414 Reactome: R-HSA-156842 CL1_0821 e0e85c13e084f324b0c281c650b7ae34 91 Pfam PF00736 EF-1 guanine nucleotide exchange domain 9 91 1.6E-20 T 30-10-2018 IPR014038 Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain GO:0003746|GO:0006414 Reactome: R-HSA-156842 CL1_1892 b8d8c4fbcee993a554e5d477793a1bf5 288 SUPERFAMILY SSF48239 16 285 5.86E-16 T 30-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid CL1_1892 b8d8c4fbcee993a554e5d477793a1bf5 288 PIRSF PIRSF016175 7 287 5.1E-128 T 30-10-2018 IPR016648 Uncharacterised conserved protein UCP016175, prenyltransferase beta-subunit-related CL1_1284 e18448d74345da570dab1458b1a5d562 449 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 366 442 7.1E-8 T 30-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CL1_1284 e18448d74345da570dab1458b1a5d562 449 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 3 132 7.2E-45 T 30-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CL1_1284 e18448d74345da570dab1458b1a5d562 449 TIGRFAM TIGR03990 Arch_GlmM: phosphoglucosamine mutase 3 442 1.1E-163 T 30-10-2018 IPR024086 Phosphoglucosamine mutase, archaeal type GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CL1_1284 e18448d74345da570dab1458b1a5d562 449 SUPERFAMILY SSF53738 150 249 1.88E-23 T 30-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CL1_1284 e18448d74345da570dab1458b1a5d562 449 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 90 99 - T 30-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CL1_1284 e18448d74345da570dab1458b1a5d562 449 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 254 357 8.4E-20 T 30-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CL1_1284 e18448d74345da570dab1458b1a5d562 449 SUPERFAMILY SSF53738 3 171 2.43E-46 T 30-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CL1_1284 e18448d74345da570dab1458b1a5d562 449 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 152 246 7.3E-20 T 30-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CL1_1284 e18448d74345da570dab1458b1a5d562 449 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 89 103 1.3E-14 T 30-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CL1_1284 e18448d74345da570dab1458b1a5d562 449 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 226 241 1.3E-14 T 30-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CL1_1284 e18448d74345da570dab1458b1a5d562 449 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 165 184 1.3E-14 T 30-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CL1_1284 e18448d74345da570dab1458b1a5d562 449 Gene3D G3DSA:3.40.120.10 247 330 1.9E-53 T 30-10-2018 CL1_1284 e18448d74345da570dab1458b1a5d562 449 Gene3D G3DSA:3.30.310.50 360 448 2.3E-21 T 30-10-2018 CL1_1284 e18448d74345da570dab1458b1a5d562 449 SUPERFAMILY SSF55957 348 446 1.44E-23 T 30-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CL1_1284 e18448d74345da570dab1458b1a5d562 449 SUPERFAMILY SSF53738 252 355 9.42E-24 T 30-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CL1_1284 e18448d74345da570dab1458b1a5d562 449 Gene3D G3DSA:3.40.120.10 165 345 1.9E-53 T 30-10-2018 CL1_1284 e18448d74345da570dab1458b1a5d562 449 Gene3D G3DSA:3.40.120.10 1 147 9.4E-51 T 30-10-2018 CL1_1284 e18448d74345da570dab1458b1a5d562 449 Hamap MF_01554_A Phosphoglucosamine mutase [glmM]. 2 446 51.742 T 30-10-2018 IPR023666 Phosphoglucosamine mutase, archaeal GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CL1_0723 6c1ceda7da468f36b63fb5d128824667 56 Pfam PF03911 Sec61beta family 11 51 1.6E-15 T 30-10-2018 IPR016482 Protein transport protein SecG/Sec61-beta/Sbh Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CL1_0723 6c1ceda7da468f36b63fb5d128824667 56 Hamap MF_00751 Preprotein translocase subunit SecG [secG]. 1 51 15.326 T 30-10-2018 IPR023531 Preprotein translocase subunit SecG CL1_1483 4916d26070ff76cd235d11729b21c2bc 105 SUPERFAMILY SSF50447 1 72 3.11E-17 T 30-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily CL1_1483 4916d26070ff76cd235d11729b21c2bc 105 Pfam PF04410 Gar1/Naf1 RNA binding region 2 58 3.3E-9 T 30-10-2018 IPR007504 H/ACA ribonucleoprotein complex, subunit Gar1/Naf1 GO:0001522|GO:0042254 CL1_1483 4916d26070ff76cd235d11729b21c2bc 105 ProDom PD064583 RNA-BINDING GAR1 COMPONENT RNP SNORNP HOMOLOG NUCLEOLAR PROCESSING RRNA VNG1366H 1 71 1.0E-16 T 30-10-2018 IPR020321 H/ACA ribonucleoprotein complex, subunit Gar1, archaea GO:0001522|GO:0042254 CL1_1483 4916d26070ff76cd235d11729b21c2bc 105 Gene3D G3DSA:2.40.10.230 1 75 5.0E-25 T 30-10-2018 IPR038664 H/ACA RNP complex subunit Gar1/Naf1, Cbf5-binding domain CL1_1895 375d20b4c71436a2b00c0a75cad4b4ac 153 SUPERFAMILY SSF52833 8 149 7.49E-45 T 30-10-2018 IPR036249 Thioredoxin-like superfamily CL1_1895 375d20b4c71436a2b00c0a75cad4b4ac 153 PIRSF PIRSF000239 4 145 5.3E-24 T 30-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CL1_1895 375d20b4c71436a2b00c0a75cad4b4ac 153 Gene3D G3DSA:3.40.30.10 2 149 1.9E-45 T 30-10-2018 CL1_1895 375d20b4c71436a2b00c0a75cad4b4ac 153 Pfam PF00578 AhpC/TSA family 8 128 7.3E-34 T 30-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CL1_0461 6181de151ab9bb29bd755cf85a9d9bf3 266 Pfam PF09754 PAC2 family 19 242 4.6E-47 T 30-10-2018 IPR019151 Proteasome assembly chaperone 2 CL1_0461 6181de151ab9bb29bd755cf85a9d9bf3 266 TIGRFAM TIGR00162 TIGR00162: TIGR00162 family protein 9 265 6.4E-75 T 30-10-2018 IPR004426 Conserved hypothetical protein CHP00062 CL1_0461 6181de151ab9bb29bd755cf85a9d9bf3 266 Gene3D G3DSA:3.40.50.10900 1 244 1.2E-74 T 30-10-2018 IPR038389 Proteasome assembly chaperone 2 superfamily CL1_0461 6181de151ab9bb29bd755cf85a9d9bf3 266 SUPERFAMILY SSF159659 2 257 1.7E-43 T 30-10-2018 CL1_1288 ace0484f9ad0dcc8c6a695710b9c5e63 146 Gene3D G3DSA:3.40.50.1010 1 127 1.4E-7 T 30-10-2018 CL1_1288 ace0484f9ad0dcc8c6a695710b9c5e63 146 SUPERFAMILY SSF88723 3 131 1.18E-14 T 30-10-2018 IPR029060 PIN-like domain superfamily CL1_1288 ace0484f9ad0dcc8c6a695710b9c5e63 146 Pfam PF10130 PIN domain 4 122 1.3E-15 T 30-10-2018 IPR002716 PIN domain CL1_1405 111db7a412d4bb81c4cf3dd4ce17b0f5 134 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 17 47 2.8E-11 T 30-10-2018 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal CL1_1405 111db7a412d4bb81c4cf3dd4ce17b0f5 134 SUPERFAMILY SSF50249 7 116 5.31E-34 T 30-10-2018 IPR012340 Nucleic acid-binding, OB-fold CL1_1405 111db7a412d4bb81c4cf3dd4ce17b0f5 134 Gene3D G3DSA:1.10.12.20 3 51 2.7E-6 T 30-10-2018 CL1_1405 111db7a412d4bb81c4cf3dd4ce17b0f5 134 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 48 111 4.3E-22 T 30-10-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal CL1_1916 42b2cac36fac525bc9e13c383f2c7906 562 Gene3D G3DSA:3.30.565.10 1 232 5.6E-68 T 30-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily CL1_1916 42b2cac36fac525bc9e13c383f2c7906 562 PIRSF PIRSF006553 1 562 5.9E-215 T 30-10-2018 IPR005734 DNA topoisomerase VI, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CL1_1916 42b2cac36fac525bc9e13c383f2c7906 562 SUPERFAMILY SSF54211 353 514 1.9E-61 T 30-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CL1_1916 42b2cac36fac525bc9e13c383f2c7906 562 SMART SM00387 31 182 2.5E-8 T 30-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase CL1_1916 42b2cac36fac525bc9e13c383f2c7906 562 Gene3D G3DSA:3.30.230.10 353 562 2.4E-72 T 30-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CL1_1916 42b2cac36fac525bc9e13c383f2c7906 562 Gene3D G3DSA:1.10.8.50 233 310 4.7E-9 T 30-10-2018 CL1_1916 42b2cac36fac525bc9e13c383f2c7906 562 TIGRFAM TIGR01052 top6b: DNA topoisomerase VI, B subunit 10 533 2.2E-232 T 30-10-2018 IPR005734 DNA topoisomerase VI, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CL1_1916 42b2cac36fac525bc9e13c383f2c7906 562 Pfam PF09239 Topoisomerase VI B subunit, transducer 354 507 5.0E-57 T 30-10-2018 IPR015320 DNA topoisomerase VI, subunit B, transducer GO:0003677|GO:0003918|GO:0006265 CL1_1916 42b2cac36fac525bc9e13c383f2c7906 562 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 32 131 6.3E-11 T 30-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase CL1_1916 42b2cac36fac525bc9e13c383f2c7906 562 Hamap MF_00322 Type 2 DNA topoisomerase 6 subunit B [top6B]. 8 550 31.827 T 30-10-2018 IPR005734 DNA topoisomerase VI, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CL1_1916 42b2cac36fac525bc9e13c383f2c7906 562 ProDom PD013790 TOPOISOMERASE ISOMERASE SUBUNIT DNA B VI TYPE II NUCLEOTIDE-BINDING ATP-BINDING 353 550 2.0E-104 T 30-10-2018 IPR015320 DNA topoisomerase VI, subunit B, transducer GO:0003677|GO:0003918|GO:0006265 CL1_1916 42b2cac36fac525bc9e13c383f2c7906 562 SUPERFAMILY SSF55874 18 230 3.01E-26 T 30-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily CL1_0641 4855ae77ce2ff7a36bad3d654d05fdd6 336 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 231 242 - T 30-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CL1_0641 4855ae77ce2ff7a36bad3d654d05fdd6 336 Pfam PF17179 4Fe-4S dicluster domain 231 322 2.9E-24 T 30-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CL1_0641 4855ae77ce2ff7a36bad3d654d05fdd6 336 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 308 319 - T 30-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CL1_0641 4855ae77ce2ff7a36bad3d654d05fdd6 336 Gene3D G3DSA:1.10.1060.10 286 334 3.4E-5 T 30-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 CL1_0641 4855ae77ce2ff7a36bad3d654d05fdd6 336 SUPERFAMILY SSF46548 226 333 4.53E-12 T 30-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 CL1_1209 0e320422e4bbec96a1a137c82cd74d58 281 Pfam PF01972 Serine dehydrogenase proteinase 9 276 1.2E-149 T 30-10-2018 IPR002825 Peptidase S49, serine-peptidase prokaryotes GO:0016021 CL1_1209 0e320422e4bbec96a1a137c82cd74d58 281 Gene3D G3DSA:3.90.226.10 62 270 3.5E-24 T 30-10-2018 CL1_1209 0e320422e4bbec96a1a137c82cd74d58 281 SUPERFAMILY SSF52096 14 241 3.32E-29 T 30-10-2018 IPR029045 ClpP/crotonase-like domain superfamily CL1_0363 2b65267aa732cd2a973048054704f668 214 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 1 12 6.9E-16 T 30-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 CL1_0363 2b65267aa732cd2a973048054704f668 214 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 98 111 6.9E-16 T 30-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 CL1_0363 2b65267aa732cd2a973048054704f668 214 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 128 144 6.9E-16 T 30-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 CL1_0363 2b65267aa732cd2a973048054704f668 214 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 174 187 6.9E-16 T 30-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 CL1_0363 2b65267aa732cd2a973048054704f668 214 Gene3D G3DSA:1.10.150.520 15 86 1.7E-48 T 30-10-2018 CL1_0363 2b65267aa732cd2a973048054704f668 214 SUPERFAMILY SSF56784 1 211 1.87E-48 T 30-10-2018 IPR036412 HAD-like superfamily CL1_0363 2b65267aa732cd2a973048054704f668 214 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 80 185 3.8E-13 T 30-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 CL1_0363 2b65267aa732cd2a973048054704f668 214 ProSitePatterns PS01228 Hypothetical cof family signature 1. 3 14 - T 30-10-2018 CL1_0363 2b65267aa732cd2a973048054704f668 214 Gene3D G3DSA:3.40.50.1000 2 206 1.7E-48 T 30-10-2018 IPR023214 HAD superfamily CL1_0363 2b65267aa732cd2a973048054704f668 214 TIGRFAM TIGR02253 CTE7: HAD hydrolase, TIGR02253 family 2 206 6.1E-53 T 30-10-2018 IPR011950 HAD-superfamily hydrolase, subfamily IA, CTE7 GO:0016787 Reactome: R-HSA-4085001 CL1_0363 2b65267aa732cd2a973048054704f668 214 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 88 179 2.5E-11 T 30-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 CL1_0363 2b65267aa732cd2a973048054704f668 214 Pfam PF13419 Haloacid dehalogenase-like hydrolase 4 185 1.6E-29 T 30-10-2018 CL1_0400 1735e154bc5b3ccc56e318ee8904fc6b 163 Gene3D G3DSA:2.10.260.30 1 69 7.0E-28 T 30-10-2018 CL1_0400 1735e154bc5b3ccc56e318ee8904fc6b 163 SUPERFAMILY SSF46906 66 138 6.67E-23 T 30-10-2018 IPR036769 Ribosomal protein L11, C-terminal domain superfamily CL1_0400 1735e154bc5b3ccc56e318ee8904fc6b 163 SUPERFAMILY SSF54747 3 82 3.92E-26 T 30-10-2018 IPR036796 Ribosomal protein L11/L12, N-terminal domain superfamily CL1_0400 1735e154bc5b3ccc56e318ee8904fc6b 163 ProSitePatterns PS00359 Ribosomal protein L11 signature. 124 139 - T 30-10-2018 IPR020785 Ribosomal protein L11, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0400 1735e154bc5b3ccc56e318ee8904fc6b 163 Pfam PF00298 Ribosomal protein L11, RNA binding domain 70 137 8.9E-23 T 30-10-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 CL1_0400 1735e154bc5b3ccc56e318ee8904fc6b 163 Gene3D G3DSA:1.10.10.250 73 163 1.2E-35 T 30-10-2018 IPR036769 Ribosomal protein L11, C-terminal domain superfamily CL1_0400 1735e154bc5b3ccc56e318ee8904fc6b 163 SMART SM00649 5 138 4.9E-65 T 30-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 CL1_0400 1735e154bc5b3ccc56e318ee8904fc6b 163 Pfam PF03946 Ribosomal protein L11, N-terminal domain 5 58 6.0E-23 T 30-10-2018 IPR020784 Ribosomal protein L11, N-terminal CL1_0400 1735e154bc5b3ccc56e318ee8904fc6b 163 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 1 139 28.506 T 30-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 CL1_1008 8cb51831e91e4a58c837f1a8fe829a31 370 SUPERFAMILY SSF51905 1 284 2.66E-34 T 30-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily CL1_1008 8cb51831e91e4a58c837f1a8fe829a31 370 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 1.0E-12 T 30-10-2018 CL1_1008 8cb51831e91e4a58c837f1a8fe829a31 370 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 134 149 1.0E-12 T 30-10-2018 CL1_1008 8cb51831e91e4a58c837f1a8fe829a31 370 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 244 259 1.0E-12 T 30-10-2018 CL1_1008 8cb51831e91e4a58c837f1a8fe829a31 370 TIGRFAM TIGR02032 GG-red-SF: geranylgeranyl reductase family 3 273 1.1E-52 T 30-10-2018 IPR011777 Geranylgeranyl reductase family GO:0016628|GO:0055114 CL1_1008 8cb51831e91e4a58c837f1a8fe829a31 370 Gene3D G3DSA:3.50.50.60 1 367 8.1E-56 T 30-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily CL1_1008 8cb51831e91e4a58c837f1a8fe829a31 370 Pfam PF01494 FAD binding domain 3 270 2.7E-16 T 30-10-2018 IPR002938 FAD-binding domain GO:0071949 CL1_1031 5d8f53608fb056feab206d757c2d4c2d 365 SMART SM00981 86 182 6.5E-15 T 30-10-2018 IPR004114 THUMP domain GO:0003723 CL1_1031 5d8f53608fb056feab206d757c2d4c2d 365 SUPERFAMILY SSF143437 93 182 1.92E-10 T 30-10-2018 CL1_1031 5d8f53608fb056feab206d757c2d4c2d 365 ProSitePatterns PS01261 Uncharacterized protein family UPF0020 signature. 223 234 - T 30-10-2018 IPR000241 Putative RNA methylase domain CL1_1031 5d8f53608fb056feab206d757c2d4c2d 365 Gene3D G3DSA:3.40.50.150 190 365 1.4E-51 T 30-10-2018 CL1_1031 5d8f53608fb056feab206d757c2d4c2d 365 SUPERFAMILY SSF53335 179 357 5.67E-38 T 30-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CL1_1031 5d8f53608fb056feab206d757c2d4c2d 365 Pfam PF01170 Putative RNA methylase family UPF0020 191 357 8.5E-37 T 30-10-2018 IPR000241 Putative RNA methylase domain CL1_1031 5d8f53608fb056feab206d757c2d4c2d 365 Gene3D G3DSA:3.30.2130.30 1 189 7.0E-83 T 30-10-2018 CL1_1031 5d8f53608fb056feab206d757c2d4c2d 365 Pfam PF02926 THUMP domain 31 182 2.5E-27 T 30-10-2018 IPR004114 THUMP domain GO:0003723 CL1_1879 120f592f0e3237db0207397cb16e2bc0 440 Pfam PF01523 Putative modulator of DNA gyrase 22 303 4.9E-51 T 30-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 CL1_1879 120f592f0e3237db0207397cb16e2bc0 440 SUPERFAMILY SSF111283 2 436 1.7E-95 T 30-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 CL1_1879 120f592f0e3237db0207397cb16e2bc0 440 Gene3D G3DSA:3.30.2290.10 2 209 3.6E-16 T 30-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal CL1_1007 51d6c3270c167d3b9886a7a98f1b445b 200 Pfam PF01470 Pyroglutamyl peptidase 1 199 2.7E-76 T 30-10-2018 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like MetaCyc: PWY-7942 CL1_1007 51d6c3270c167d3b9886a7a98f1b445b 200 PIRSF PIRSF015592 1 200 3.7E-78 T 30-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 CL1_1007 51d6c3270c167d3b9886a7a98f1b445b 200 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 60 72 8.4E-42 T 30-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 CL1_1007 51d6c3270c167d3b9886a7a98f1b445b 200 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 160 172 8.4E-42 T 30-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 CL1_1007 51d6c3270c167d3b9886a7a98f1b445b 200 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 3 26 8.4E-42 T 30-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 CL1_1007 51d6c3270c167d3b9886a7a98f1b445b 200 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 130 146 8.4E-42 T 30-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 CL1_1007 51d6c3270c167d3b9886a7a98f1b445b 200 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 78 98 8.4E-42 T 30-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 CL1_1007 51d6c3270c167d3b9886a7a98f1b445b 200 TIGRFAM TIGR00504 pyro_pdase: pyroglutamyl-peptidase I 2 198 1.5E-76 T 30-10-2018 IPR029762 Pyroglutamyl peptidase I, bacterial-type GO:0005829|GO:0006508|GO:0008234|GO:0016920 MetaCyc: PWY-7942 CL1_1007 51d6c3270c167d3b9886a7a98f1b445b 200 Hamap MF_00417 Pyrrolidone-carboxylate peptidase [pcp]. 1 198 37.782 T 30-10-2018 IPR029762 Pyroglutamyl peptidase I, bacterial-type GO:0005829|GO:0006508|GO:0008234|GO:0016920 MetaCyc: PWY-7942 CL1_1007 51d6c3270c167d3b9886a7a98f1b445b 200 ProSitePatterns PS01333 Pyrrolidone-carboxylate peptidase glutamic acid active site. 67 83 - T 30-10-2018 IPR033693 Pyroglutamyl peptidase I, Glu active site MetaCyc: PWY-7942 CL1_1007 51d6c3270c167d3b9886a7a98f1b445b 200 Gene3D G3DSA:3.40.630.20 1 200 6.2E-77 T 30-10-2018 IPR036440 Peptidase C15, pyroglutamyl peptidase I-like superfamily MetaCyc: PWY-7942 CL1_1007 51d6c3270c167d3b9886a7a98f1b445b 200 SUPERFAMILY SSF53182 1 199 3.79E-70 T 30-10-2018 IPR036440 Peptidase C15, pyroglutamyl peptidase I-like superfamily MetaCyc: PWY-7942 CL1_1007 51d6c3270c167d3b9886a7a98f1b445b 200 ProSitePatterns PS01334 Pyrrolidone-carboxylate peptidase cysteine active site. 128 142 - T 30-10-2018 IPR033694 Pyroglutamyl peptidase I, Cys active site MetaCyc: PWY-7942 CL1_0365 417f8c9026516119628580d357012d0a 406 Pfam PF01380 SIS domain 246 347 2.1E-21 T 30-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CL1_0365 417f8c9026516119628580d357012d0a 406 SUPERFAMILY SSF53697 215 404 6.88E-39 T 30-10-2018 CL1_0365 417f8c9026516119628580d357012d0a 406 Gene3D G3DSA:3.40.50.10490 213 406 3.0E-58 T 30-10-2018 CL1_0365 417f8c9026516119628580d357012d0a 406 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 3 203 1.0E-27 T 30-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CL1_0365 417f8c9026516119628580d357012d0a 406 SUPERFAMILY SSF51366 2 214 1.96E-45 T 30-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 CL1_0365 417f8c9026516119628580d357012d0a 406 TIGRFAM TIGR03127 RuMP_HxlB: 6-phospho 3-hexuloisomerase 219 406 3.3E-74 T 30-10-2018 IPR017552 3-hexulose-6-phosphate isomerase GO:0016853 CL1_0365 417f8c9026516119628580d357012d0a 406 SMART SM00934 2 203 1.5E-45 T 30-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CL1_0365 417f8c9026516119628580d357012d0a 406 TIGRFAM TIGR03128 RuMP_HxlA: 3-hexulose-6-phosphate synthase 3 206 3.8E-83 T 30-10-2018 IPR017553 3-hexulose-6-phosphate synthase GO:0005975|GO:0043801 KEGG: 00030+4.1.2.43|KEGG: 00680+4.1.2.43|MetaCyc: PWY-1861|MetaCyc: PWY-7796 CL1_0365 417f8c9026516119628580d357012d0a 406 Gene3D G3DSA:3.20.20.70 1 208 7.1E-76 T 30-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CL1_1036 d86656a743440d12f0218a1be36db7e5 469 SUPERFAMILY SSF51735 6 135 2.06E-36 T 30-10-2018 IPR036291 NAD(P)-binding domain superfamily CL1_1036 d86656a743440d12f0218a1be36db7e5 469 SMART SM00881 9 107 8.3E-38 T 30-10-2018 IPR003781 CoA-binding GO:0048037 CL1_1036 d86656a743440d12f0218a1be36db7e5 469 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 161 297 1.3E-56 T 30-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain CL1_1036 d86656a743440d12f0218a1be36db7e5 469 Gene3D G3DSA:3.40.50.261 302 466 1.1E-44 T 30-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CL1_1036 d86656a743440d12f0218a1be36db7e5 469 SUPERFAMILY SSF52210 304 463 2.88E-35 T 30-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CL1_1036 d86656a743440d12f0218a1be36db7e5 469 SUPERFAMILY SSF52210 136 298 7.33E-42 T 30-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CL1_1036 d86656a743440d12f0218a1be36db7e5 469 Gene3D G3DSA:3.40.50.261 136 300 2.1E-59 T 30-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CL1_1036 d86656a743440d12f0218a1be36db7e5 469 Gene3D G3DSA:3.40.50.720 4 134 2.0E-43 T 30-10-2018 CL1_1036 d86656a743440d12f0218a1be36db7e5 469 Pfam PF13380 CoA binding domain 13 139 1.1E-22 T 30-10-2018 IPR003781 CoA-binding GO:0048037 CL1_1967 91c4d95ea8c1c4d2352e411a8ecc5c4d 270 SUPERFAMILY SSF48317 59 224 3.27E-10 T 30-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily CL1_1967 91c4d95ea8c1c4d2352e411a8ecc5c4d 270 Pfam PF14378 PAP2 superfamily 63 212 4.3E-9 T 30-10-2018 IPR026841 Inositolphosphotransferase Aur1/Ipt1 CL1_1967 91c4d95ea8c1c4d2352e411a8ecc5c4d 270 Gene3D G3DSA:1.20.144.10 143 237 5.4E-6 T 30-10-2018 CL1_1525 03440fc58852576ac72bb93a5836e92f 120 Hamap MF_00757 Ribonuclease P protein component 4 [rnp4]. 10 109 26.309 T 30-10-2018 IPR016432 Ribonuclease P, protein component 4 GO:0001682|GO:0004526 CL1_1525 03440fc58852576ac72bb93a5836e92f 120 PIRSF PIRSF004878 1 116 2.1E-42 T 30-10-2018 IPR016432 Ribonuclease P, protein component 4 GO:0001682|GO:0004526 CL1_1525 03440fc58852576ac72bb93a5836e92f 120 Pfam PF04032 RNAse P Rpr2/Rpp21/SNM1 subunit domain 21 100 1.5E-16 T 30-10-2018 IPR007175 RNAse P, Rpr2/Rpp21 subunit Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CL1_1525 03440fc58852576ac72bb93a5836e92f 120 Gene3D G3DSA:2.20.25.200 64 118 2.4E-24 T 30-10-2018 CL1_1525 03440fc58852576ac72bb93a5836e92f 120 Gene3D G3DSA:1.20.5.420 5 63 6.2E-22 T 30-10-2018 CL1_0094 9c4318187c623ac7cbef719528f400de 456 PIRSF PIRSF006603 5 456 3.3E-108 T 30-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CL1_0094 9c4318187c623ac7cbef719528f400de 456 TIGRFAM TIGR00797 matE: MATE efflux family protein 17 419 2.9E-125 T 30-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CL1_0094 9c4318187c623ac7cbef719528f400de 456 Pfam PF01554 MatE 17 177 6.7E-38 T 30-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CL1_0094 9c4318187c623ac7cbef719528f400de 456 Pfam PF01554 MatE 241 407 3.3E-37 T 30-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CL1_0387 3bd53425aa727149ecd659434e82f90c 67 SUPERFAMILY SSF54862 3 64 1.81E-17 T 30-10-2018 CL1_0387 3bd53425aa727149ecd659434e82f90c 67 Pfam PF00037 4Fe-4S binding domain 38 58 1.4E-8 T 30-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CL1_0387 3bd53425aa727149ecd659434e82f90c 67 Pfam PF00037 4Fe-4S binding domain 7 30 8.6E-7 T 30-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CL1_0387 3bd53425aa727149ecd659434e82f90c 67 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 14 25 - T 30-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CL1_0387 3bd53425aa727149ecd659434e82f90c 67 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 43 54 - T 30-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CL1_0387 3bd53425aa727149ecd659434e82f90c 67 Gene3D G3DSA:3.30.70.20 3 65 6.2E-16 T 30-10-2018 CL1_0082 0ab11fbaa3b5adc667ba70ea2640171b 171 ProDom PD007457 TRANSFERASE ADENOSYLTRANSFERASE COBALAMIN ATP:COBIALAMIN ADENOSYLTRANSFERASE PDUO TYPE RELATED ACIDURIA YVQK 19 165 2.0E-63 T 30-10-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 CL1_0082 0ab11fbaa3b5adc667ba70ea2640171b 171 TIGRFAM TIGR00636 PduO_Nterm: ATP:cob(I)alamin adenosyltransferase 4 169 1.5E-57 T 30-10-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 CL1_0082 0ab11fbaa3b5adc667ba70ea2640171b 171 Gene3D G3DSA:1.20.1200.10 25 171 2.2E-48 T 30-10-2018 IPR036451 Cobalamin adenosyltransferase-like superfamily KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 CL1_0082 0ab11fbaa3b5adc667ba70ea2640171b 171 Pfam PF01923 Cobalamin adenosyltransferase 3 159 9.7E-48 T 30-10-2018 IPR016030 Cobalamin adenosyltransferase-like KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 CL1_0082 0ab11fbaa3b5adc667ba70ea2640171b 171 SUPERFAMILY SSF89028 1 165 7.26E-50 T 30-10-2018 IPR036451 Cobalamin adenosyltransferase-like superfamily KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 CL1_1144 6df9ca2899f6092c0dcd94f4a20dfa14 351 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 21 40 1.1E-22 T 30-10-2018 CL1_1144 6df9ca2899f6092c0dcd94f4a20dfa14 351 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 300 322 1.1E-22 T 30-10-2018 CL1_1144 6df9ca2899f6092c0dcd94f4a20dfa14 351 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 118 136 1.1E-22 T 30-10-2018 CL1_1144 6df9ca2899f6092c0dcd94f4a20dfa14 351 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 173 191 1.1E-22 T 30-10-2018 CL1_1144 6df9ca2899f6092c0dcd94f4a20dfa14 351 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 275 291 1.1E-22 T 30-10-2018 CL1_1144 6df9ca2899f6092c0dcd94f4a20dfa14 351 SUPERFAMILY SSF51971 17 284 4.59E-58 T 30-10-2018 CL1_1144 6df9ca2899f6092c0dcd94f4a20dfa14 351 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 19 335 5.3E-36 T 30-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CL1_1144 6df9ca2899f6092c0dcd94f4a20dfa14 351 Gene3D G3DSA:3.40.50.720 14 140 1.4E-19 T 30-10-2018 CL1_1144 6df9ca2899f6092c0dcd94f4a20dfa14 351 Gene3D G3DSA:3.50.50.60 141 283 1.2E-38 T 30-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily CL1_1144 6df9ca2899f6092c0dcd94f4a20dfa14 351 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 310 328 6.0E-13 T 30-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CL1_1144 6df9ca2899f6092c0dcd94f4a20dfa14 351 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 169 193 6.0E-13 T 30-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CL1_1144 6df9ca2899f6092c0dcd94f4a20dfa14 351 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 20 42 6.0E-13 T 30-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CL1_1996 c6066dc54d9fe8c53797ff8c8c553f46 274 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 235 1.8E-19 T 30-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CL1_1996 c6066dc54d9fe8c53797ff8c8c553f46 274 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 134 152 1.2E-20 T 30-10-2018 CL1_1996 c6066dc54d9fe8c53797ff8c8c553f46 274 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 1.2E-20 T 30-10-2018 CL1_1996 c6066dc54d9fe8c53797ff8c8c553f46 274 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 101 119 1.2E-20 T 30-10-2018 CL1_1996 c6066dc54d9fe8c53797ff8c8c553f46 274 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 212 228 1.2E-20 T 30-10-2018 CL1_1996 c6066dc54d9fe8c53797ff8c8c553f46 274 Gene3D G3DSA:3.50.50.60 6 263 6.3E-43 T 30-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily CL1_1996 c6066dc54d9fe8c53797ff8c8c553f46 274 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 102 110 3.6E-11 T 30-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CL1_1996 c6066dc54d9fe8c53797ff8c8c553f46 274 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 36 51 3.6E-11 T 30-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CL1_1996 c6066dc54d9fe8c53797ff8c8c553f46 274 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 57 67 3.6E-11 T 30-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CL1_1996 c6066dc54d9fe8c53797ff8c8c553f46 274 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 231 249 3.6E-11 T 30-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CL1_1996 c6066dc54d9fe8c53797ff8c8c553f46 274 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 3 25 3.6E-11 T 30-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CL1_1996 c6066dc54d9fe8c53797ff8c8c553f46 274 Gene3D G3DSA:3.50.50.60 113 220 6.3E-43 T 30-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily CL1_1996 c6066dc54d9fe8c53797ff8c8c553f46 274 SUPERFAMILY SSF51905 4 267 4.53E-33 T 30-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily CL1_0824 2c43017697dedbe48ac1040bfc50e31f 200 SUPERFAMILY SSF51161 3 157 1.07E-45 T 30-10-2018 IPR011004 Trimeric LpxA-like superfamily CL1_0824 2c43017697dedbe48ac1040bfc50e31f 200 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 3 31 3.2E-5 T 30-10-2018 IPR001451 Hexapeptide repeat CL1_0824 2c43017697dedbe48ac1040bfc50e31f 200 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 104 136 2.8E-6 T 30-10-2018 IPR001451 Hexapeptide repeat CL1_0824 2c43017697dedbe48ac1040bfc50e31f 200 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 35 67 2.0E-9 T 30-10-2018 IPR001451 Hexapeptide repeat CL1_0824 2c43017697dedbe48ac1040bfc50e31f 200 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 110 138 - T 30-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 CL1_0824 2c43017697dedbe48ac1040bfc50e31f 200 Gene3D G3DSA:2.160.10.10 1 151 1.5E-46 T 30-10-2018 CL1_1467 536967c7e1bdb048a0ff64e178246773 417 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 30 357 1.8E-112 T 30-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 CL1_1467 536967c7e1bdb048a0ff64e178246773 417 SUPERFAMILY SSF52490 36 239 5.23E-57 T 30-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 CL1_1467 536967c7e1bdb048a0ff64e178246773 417 SUPERFAMILY SSF55307 238 352 6.18E-35 T 30-10-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 CL1_1467 536967c7e1bdb048a0ff64e178246773 417 ProSitePatterns PS01135 FtsZ protein signature 2. 121 142 - T 30-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 CL1_1467 536967c7e1bdb048a0ff64e178246773 417 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 33 393 33.601 T 30-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 CL1_1467 536967c7e1bdb048a0ff64e178246773 417 SMART SM00865 238 355 2.4E-38 T 30-10-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-380320 CL1_1467 536967c7e1bdb048a0ff64e178246773 417 Gene3D G3DSA:3.40.50.1440 34 347 3.0E-99 T 30-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 CL1_1467 536967c7e1bdb048a0ff64e178246773 417 Pfam PF12327 FtsZ family, C-terminal domain 253 347 2.5E-24 T 30-10-2018 IPR024757 Cell division protein FtsZ, C-terminal CL1_1467 536967c7e1bdb048a0ff64e178246773 417 ProSitePatterns PS01134 FtsZ protein signature 1. 68 102 - T 30-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 CL1_1467 536967c7e1bdb048a0ff64e178246773 417 PRINTS PR00423 Cell division protein FtsZ signature 122 142 7.3E-36 T 30-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CL1_1467 536967c7e1bdb048a0ff64e178246773 417 PRINTS PR00423 Cell division protein FtsZ signature 243 264 7.3E-36 T 30-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CL1_1467 536967c7e1bdb048a0ff64e178246773 417 PRINTS PR00423 Cell division protein FtsZ signature 220 242 7.3E-36 T 30-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CL1_1467 536967c7e1bdb048a0ff64e178246773 417 PRINTS PR00423 Cell division protein FtsZ signature 158 179 7.3E-36 T 30-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CL1_1467 536967c7e1bdb048a0ff64e178246773 417 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 37 205 7.3E-44 T 30-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CL1_1467 536967c7e1bdb048a0ff64e178246773 417 SMART SM00864 37 236 1.1E-84 T 30-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CL1_1494 4bb937814b4083705607e39bb8179378 204 Gene3D G3DSA:1.10.1670.10 15 197 5.6E-27 T 30-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 CL1_1494 4bb937814b4083705607e39bb8179378 204 SMART SM00478 41 197 6.2E-21 T 30-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CL1_1494 4bb937814b4083705607e39bb8179378 204 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 45 147 1.8E-6 T 30-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CL1_1494 4bb937814b4083705607e39bb8179378 204 SUPERFAMILY SSF48150 14 148 3.14E-31 T 30-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CL1_1494 4bb937814b4083705607e39bb8179378 204 Gene3D G3DSA:1.10.340.30 22 136 5.6E-27 T 30-10-2018 CL1_1808 711b34b76028e6cdede6cd1697259d87 424 Pfam PF00375 Sodium:dicarboxylate symporter family 16 412 1.2E-124 T 30-10-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CL1_1808 711b34b76028e6cdede6cd1697259d87 424 Gene3D G3DSA:1.10.3860.10 2 424 5.6E-161 T 30-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 CL1_1808 711b34b76028e6cdede6cd1697259d87 424 SUPERFAMILY SSF118215 16 414 5.62E-121 T 30-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 CL1_1808 711b34b76028e6cdede6cd1697259d87 424 PRINTS PR00173 Glutamate-aspartate symporter signature 49 69 6.8E-44 T 30-10-2018 CL1_1808 711b34b76028e6cdede6cd1697259d87 424 PRINTS PR00173 Glutamate-aspartate symporter signature 298 324 6.8E-44 T 30-10-2018 CL1_1808 711b34b76028e6cdede6cd1697259d87 424 PRINTS PR00173 Glutamate-aspartate symporter signature 8 28 6.8E-44 T 30-10-2018 CL1_1808 711b34b76028e6cdede6cd1697259d87 424 PRINTS PR00173 Glutamate-aspartate symporter signature 197 216 6.8E-44 T 30-10-2018 CL1_1808 711b34b76028e6cdede6cd1697259d87 424 PRINTS PR00173 Glutamate-aspartate symporter signature 333 352 6.8E-44 T 30-10-2018 CL1_1808 711b34b76028e6cdede6cd1697259d87 424 PRINTS PR00173 Glutamate-aspartate symporter signature 360 380 6.8E-44 T 30-10-2018 CL1_1808 711b34b76028e6cdede6cd1697259d87 424 PRINTS PR00173 Glutamate-aspartate symporter signature 78 103 6.8E-44 T 30-10-2018 CL1_1808 711b34b76028e6cdede6cd1697259d87 424 ProSitePatterns PS00713 Sodium:dicarboxylate symporter family signature 1. 41 56 - T 30-10-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site CL1_1030 781a4adec3cdb0865dda42bf8f59b227 488 SMART SM00729 97 305 0.0058 T 30-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 CL1_1030 781a4adec3cdb0865dda42bf8f59b227 488 SUPERFAMILY SSF102114 94 406 6.54E-52 T 30-10-2018 CL1_1030 781a4adec3cdb0865dda42bf8f59b227 488 Pfam PF04055 Radical SAM superfamily 103 267 6.1E-16 T 30-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CL1_1030 781a4adec3cdb0865dda42bf8f59b227 488 Gene3D G3DSA:3.20.20.70 95 443 4.8E-77 T 30-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CL1_1030 781a4adec3cdb0865dda42bf8f59b227 488 Pfam PF13353 4Fe-4S single cluster domain 99 217 6.2E-7 T 30-10-2018 CL1_1030 781a4adec3cdb0865dda42bf8f59b227 488 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 338 425 5.6E-18 T 30-10-2018 IPR023885 4Fe4S-binding SPASM domain CL1_0500 45ab275586ee63ed851bb331773de99f 441 TIGRFAM TIGR03385 CoA_CoA_reduc: CoA-disulfide reductase 5 436 1.4E-179 T 30-10-2018 IPR017758 Coenzyme A disulphide reductase GO:0003756|GO:0050451|GO:0050660|GO:0050661|GO:0055114 CL1_0500 45ab275586ee63ed851bb331773de99f 441 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 9.7E-23 T 30-10-2018 CL1_0500 45ab275586ee63ed851bb331773de99f 441 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 149 174 9.7E-23 T 30-10-2018 CL1_0500 45ab275586ee63ed851bb331773de99f 441 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 384 399 9.7E-23 T 30-10-2018 CL1_0500 45ab275586ee63ed851bb331773de99f 441 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 274 281 9.7E-23 T 30-10-2018 CL1_0500 45ab275586ee63ed851bb331773de99f 441 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 233 247 9.7E-23 T 30-10-2018 CL1_0500 45ab275586ee63ed851bb331773de99f 441 SUPERFAMILY SSF55424 320 438 1.32E-29 T 30-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 CL1_0500 45ab275586ee63ed851bb331773de99f 441 Gene3D G3DSA:3.50.50.60 43 241 1.4E-115 T 30-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily CL1_0500 45ab275586ee63ed851bb331773de99f 441 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 326 427 1.7E-18 T 30-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CL1_0500 45ab275586ee63ed851bb331773de99f 441 Gene3D G3DSA:3.50.50.60 320 441 6.4E-44 T 30-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily CL1_0500 45ab275586ee63ed851bb331773de99f 441 SUPERFAMILY SSF51905 3 344 9.5E-49 T 30-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily CL1_0500 45ab275586ee63ed851bb331773de99f 441 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 232 248 1.5E-29 T 30-10-2018 CL1_0500 45ab275586ee63ed851bb331773de99f 441 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 259 281 1.5E-29 T 30-10-2018 CL1_0500 45ab275586ee63ed851bb331773de99f 441 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 1.5E-29 T 30-10-2018 CL1_0500 45ab275586ee63ed851bb331773de99f 441 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 149 167 1.5E-29 T 30-10-2018 CL1_0500 45ab275586ee63ed851bb331773de99f 441 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 102 120 1.5E-29 T 30-10-2018 CL1_0500 45ab275586ee63ed851bb331773de99f 441 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 303 3.0E-61 T 30-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CL1_0500 45ab275586ee63ed851bb331773de99f 441 Gene3D G3DSA:3.50.50.60 5 314 1.4E-115 T 30-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily CL1_0470 6a3c07e6a41202fa5fa3500bdedcff5b 453 SUPERFAMILY SSF53613 2 452 5.38E-150 T 30-10-2018 IPR029056 Ribokinase-like CL1_0470 6a3c07e6a41202fa5fa3500bdedcff5b 453 Gene3D G3DSA:3.30.1110.20 31 203 2.9E-153 T 30-10-2018 CL1_0470 6a3c07e6a41202fa5fa3500bdedcff5b 453 Hamap MF_00809 ADP-dependent glucokinase [glkA]. 1 453 58.744 T 30-10-2018 IPR031299 ADP-dependent glucokinase, archaeal KEGG: 00010+2.7.1.147|MetaCyc: PWY-6855 CL1_0470 6a3c07e6a41202fa5fa3500bdedcff5b 453 PIRSF PIRSF015883 10 453 1.9E-159 T 30-10-2018 IPR015990 ADP-specific phosphofructokinase/glucokinase, archaeal GO:0000287|GO:0006096|GO:0016773 CL1_0470 6a3c07e6a41202fa5fa3500bdedcff5b 453 Pfam PF04587 ADP-specific Phosphofructokinase/Glucokinase conserved region 24 447 3.9E-95 T 30-10-2018 IPR007666 ADP-specific phosphofructokinase/glucokinase GO:0005975|GO:0016773 Reactome: R-HSA-70171 CL1_0470 6a3c07e6a41202fa5fa3500bdedcff5b 453 Gene3D G3DSA:3.40.1190.20 24 447 2.9E-153 T 30-10-2018 IPR029056 Ribokinase-like CL1_1674 43fd62f5656b24d3956e3571e2f0276a 143 Pfam PF02933 Cell division protein 48 (CDC48), domain 2 15 73 1.8E-5 T 30-10-2018 IPR004201 CDC48, domain 2 CL1_1674 43fd62f5656b24d3956e3571e2f0276a 143 Gene3D G3DSA:3.10.330.10 1 77 2.8E-26 T 30-10-2018 CL1_1674 43fd62f5656b24d3956e3571e2f0276a 143 Gene3D G3DSA:2.40.10.360 80 143 2.8E-12 T 30-10-2018 CL1_1674 43fd62f5656b24d3956e3571e2f0276a 143 SUPERFAMILY SSF54585 2 74 1.67E-12 T 30-10-2018 IPR029067 CDC48 domain 2-like superfamily CL1_1674 43fd62f5656b24d3956e3571e2f0276a 143 SMART SM01072 12 74 1.1E-7 T 30-10-2018 IPR004201 CDC48, domain 2 CL1_1133 afe79f4b6a0a028ddea1cd372bee7577 172 SUPERFAMILY SSF56770 32 161 4.58E-53 T 30-10-2018 CL1_1133 afe79f4b6a0a028ddea1cd372bee7577 172 Gene3D G3DSA:3.40.50.12280 14 171 1.4E-51 T 30-10-2018 CL1_1133 afe79f4b6a0a028ddea1cd372bee7577 172 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 44 153 9.0E-28 T 30-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CL1_1712 ff27c979a0c6a4ce6fc49b0cde7b4484 430 SUPERFAMILY SSF55681 110 425 1.49E-88 T 30-10-2018 CL1_1712 ff27c979a0c6a4ce6fc49b0cde7b4484 430 Gene3D G3DSA:3.30.930.10 105 430 1.7E-117 T 30-10-2018 CL1_1712 ff27c979a0c6a4ce6fc49b0cde7b4484 430 SUPERFAMILY SSF50249 4 99 1.68E-26 T 30-10-2018 IPR012340 Nucleic acid-binding, OB-fold CL1_1712 ff27c979a0c6a4ce6fc49b0cde7b4484 430 PRINTS PR01042 Aspartyl-tRNA synthetase signature 345 361 9.7E-15 T 30-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CL1_1712 ff27c979a0c6a4ce6fc49b0cde7b4484 430 PRINTS PR01042 Aspartyl-tRNA synthetase signature 181 193 9.7E-15 T 30-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CL1_1712 ff27c979a0c6a4ce6fc49b0cde7b4484 430 PRINTS PR01042 Aspartyl-tRNA synthetase signature 385 399 9.7E-15 T 30-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CL1_1712 ff27c979a0c6a4ce6fc49b0cde7b4484 430 PRINTS PR01042 Aspartyl-tRNA synthetase signature 197 210 9.7E-15 T 30-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CL1_1712 ff27c979a0c6a4ce6fc49b0cde7b4484 430 Pfam PF01336 OB-fold nucleic acid binding domain 19 97 2.5E-16 T 30-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 CL1_1712 ff27c979a0c6a4ce6fc49b0cde7b4484 430 Gene3D G3DSA:2.40.50.140 1 101 7.2E-30 T 30-10-2018 CL1_1712 ff27c979a0c6a4ce6fc49b0cde7b4484 430 TIGRFAM TIGR00457 asnS: asparagine--tRNA ligase 14 429 1.4E-128 T 30-10-2018 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22 CL1_1712 ff27c979a0c6a4ce6fc49b0cde7b4484 430 Pfam PF00152 tRNA synthetases class II (D, K and N) 110 424 7.8E-87 T 30-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CL1_1436 2afc6f00eb402b7807a855b6eabc44f8 134 Pfam PF01597 Glycine cleavage H-protein 13 132 3.4E-50 T 30-10-2018 IPR033753 Glycine cleavage system H-protein/Simiate CL1_1436 2afc6f00eb402b7807a855b6eabc44f8 134 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 54 83 - T 30-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 CL1_1436 2afc6f00eb402b7807a855b6eabc44f8 134 Gene3D G3DSA:2.40.50.100 2 131 5.4E-52 T 30-10-2018 CL1_1436 2afc6f00eb402b7807a855b6eabc44f8 134 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 11 132 2.9E-47 T 30-10-2018 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 CL1_1436 2afc6f00eb402b7807a855b6eabc44f8 134 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 10 132 41.059 T 30-10-2018 IPR002930 Glycine cleavage system H-protein GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 CL1_1436 2afc6f00eb402b7807a855b6eabc44f8 134 SUPERFAMILY SSF51230 10 133 8.25E-42 T 30-10-2018 IPR011053 Single hybrid motif CL1_1515 a79eee6d11985161775f9d046af4b818 147 ProSitePatterns PS01318 TsaA-like domain signature. 73 84 - T 30-10-2018 IPR023368 Uncharacterised protein family UPF0066, conserved site CL1_1515 a79eee6d11985161775f9d046af4b818 147 TIGRFAM TIGR00104 tRNA_TsaA: tRNA-Thr(GGU) m(6)t(6)A37 methyltransferase TsaA 16 129 2.9E-35 T 30-10-2018 IPR023370 YaeB-like, N-terminal domain CL1_1515 a79eee6d11985161775f9d046af4b818 147 Gene3D G3DSA:2.40.30.70 5 143 1.1E-30 T 30-10-2018 IPR036414 YaeB, N-terminal domain superfamily CL1_1515 a79eee6d11985161775f9d046af4b818 147 SUPERFAMILY SSF118196 5 129 3.66E-38 T 30-10-2018 IPR036413 YaeB-like superfamily CL1_1515 a79eee6d11985161775f9d046af4b818 147 Pfam PF01980 Uncharacterised protein family UPF0066 16 125 5.6E-30 T 30-10-2018 IPR023370 YaeB-like, N-terminal domain CL1_1887 cf719cd97249fe1be0c5dcc9e9baa23c 119 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 4 113 6.6E-25 T 30-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 CL1_1887 cf719cd97249fe1be0c5dcc9e9baa23c 119 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 2 118 19.506 T 30-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 CL1_1887 cf719cd97249fe1be0c5dcc9e9baa23c 119 TIGRFAM TIGR00494 crcB: protein CrcB 4 117 4.1E-28 T 30-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 CL1_0199 dabd301c35c4a4fc22d6308f748014fe 195 SUPERFAMILY SSF56770 18 167 1.18E-52 T 30-10-2018 CL1_0199 dabd301c35c4a4fc22d6308f748014fe 195 TIGRFAM TIGR01957 nuoB_fam: NADH-quinone oxidoreductase, B subunit 20 154 1.5E-44 T 30-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CL1_0199 dabd301c35c4a4fc22d6308f748014fe 195 Gene3D G3DSA:3.40.50.12280 2 175 5.1E-53 T 30-10-2018 CL1_0199 dabd301c35c4a4fc22d6308f748014fe 195 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 37 148 1.9E-19 T 30-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CL1_0232 88670b1263e765ca2f6073856b253418 116 TIGRFAM TIGR02338 gimC_beta: prefoldin, beta subunit 4 112 5.2E-40 T 30-10-2018 IPR012713 Prefoldin subunit beta GO:0006457|GO:0016272|GO:0051082 CL1_0232 88670b1263e765ca2f6073856b253418 116 Hamap MF_00307 Prefoldin subunit beta [pfdB]. 1 116 50.05 T 30-10-2018 IPR012713 Prefoldin subunit beta GO:0006457|GO:0016272|GO:0051082 CL1_0232 88670b1263e765ca2f6073856b253418 116 Pfam PF01920 Prefoldin subunit 9 111 1.6E-23 T 30-10-2018 IPR002777 Prefoldin beta-like GO:0006457|GO:0016272|GO:0051082 Reactome: R-HSA-389957 CL1_0232 88670b1263e765ca2f6073856b253418 116 Gene3D G3DSA:1.10.287.370 1 116 1.8E-39 T 30-10-2018 IPR009053 Prefoldin CL1_0232 88670b1263e765ca2f6073856b253418 116 SUPERFAMILY SSF46579 6 110 1.7E-22 T 30-10-2018 CL1_0613 4520627ba3242f5f7641c61ce56aea22 56 Hamap MF_01364_A 30S ribosomal protein S14 type Z [rpsZ]. 2 56 17.461 T 30-10-2018 IPR023676 Ribosomal protein S14, type Z, archaeal GO:0003723|GO:0003735|GO:0006412|GO:0015935 CL1_0613 4520627ba3242f5f7641c61ce56aea22 56 Gene3D G3DSA:4.10.830.10 1 56 2.2E-20 T 30-10-2018 CL1_0613 4520627ba3242f5f7641c61ce56aea22 56 Pfam PF00253 Ribosomal protein S14p/S29e 8 55 1.9E-9 T 30-10-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CL1_0613 4520627ba3242f5f7641c61ce56aea22 56 ProSitePatterns PS00527 Ribosomal protein S14 signature. 23 44 - T 30-10-2018 IPR018271 Ribosomal protein S14, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0426 ecd6c01fc9275ad19df9834101301378 114 SUPERFAMILY SSF160148 46 113 9.02E-19 T 30-10-2018 IPR036593 CPE0013-like superfamily CL1_0426 ecd6c01fc9275ad19df9834101301378 114 SUPERFAMILY SSF53706 2 51 5.1E-8 T 30-10-2018 CL1_0426 ecd6c01fc9275ad19df9834101301378 114 Gene3D G3DSA:2.20.25.90 2 48 3.4E-5 T 30-10-2018 CL1_0426 ecd6c01fc9275ad19df9834101301378 114 Gene3D G3DSA:3.10.530.10 49 112 1.2E-15 T 30-10-2018 IPR036593 CPE0013-like superfamily CL1_0426 ecd6c01fc9275ad19df9834101301378 114 Pfam PF07892 Protein of unknown function (DUF1667) 34 112 6.3E-27 T 30-10-2018 IPR012460 Protein of unknown function DUF1667 CL1_1470 84f5be7f0a642c45ff92c308bcae2bdc 151 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 11 77 9.7E-22 T 30-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CL1_1470 84f5be7f0a642c45ff92c308bcae2bdc 151 Hamap MF_02115 FAD synthase [ribL]. 10 150 29.846 T 30-10-2018 IPR024902 FAD synthase RibL GO:0003919|GO:0006747|GO:0046444 KEGG: 00740+2.7.7.2|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CL1_1470 84f5be7f0a642c45ff92c308bcae2bdc 151 SUPERFAMILY SSF52374 11 144 2.95E-28 T 30-10-2018 CL1_1470 84f5be7f0a642c45ff92c308bcae2bdc 151 Gene3D G3DSA:3.40.50.620 1 151 1.3E-41 T 30-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CL1_1470 84f5be7f0a642c45ff92c308bcae2bdc 151 Pfam PF01467 Cytidylyltransferase-like 13 144 2.0E-23 T 30-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CL1_0566 4083c9018692abc60e9b5540dae78679 390 TIGRFAM TIGR02151 IPP_isom_2: isopentenyl-diphosphate delta-isomerase, type 2 31 370 3.9E-132 T 30-10-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 CL1_0566 4083c9018692abc60e9b5540dae78679 390 SMART SM01240 48 367 8.7E-4 T 30-10-2018 CL1_0566 4083c9018692abc60e9b5540dae78679 390 Hamap MF_00354 Isopentenyl-diphosphate delta-isomerase [fni]. 28 371 41.218 T 30-10-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 CL1_0566 4083c9018692abc60e9b5540dae78679 390 SUPERFAMILY SSF51395 50 386 1.2E-80 T 30-10-2018 CL1_0566 4083c9018692abc60e9b5540dae78679 390 Gene3D G3DSA:3.20.20.70 28 390 4.8E-129 T 30-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CL1_0566 4083c9018692abc60e9b5540dae78679 390 PIRSF PIRSF003314 25 381 7.5E-134 T 30-10-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 CL1_0566 4083c9018692abc60e9b5540dae78679 390 Pfam PF01070 FMN-dependent dehydrogenase 32 123 1.9E-8 T 30-10-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 Reactome: R-HSA-9033241 CL1_0566 4083c9018692abc60e9b5540dae78679 390 Pfam PF01070 FMN-dependent dehydrogenase 204 364 2.4E-16 T 30-10-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 Reactome: R-HSA-9033241 CL1_0938 354a32d33131d6b65b0f3b83e767b87c 507 Gene3D G3DSA:1.20.1640.10 313 501 3.2E-15 T 30-10-2018 CL1_0938 354a32d33131d6b65b0f3b83e767b87c 507 Pfam PF02355 Protein export membrane protein 330 490 6.0E-18 T 30-10-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial CL1_0938 354a32d33131d6b65b0f3b83e767b87c 507 Pfam PF07549 SecD/SecF GG Motif 28 53 4.1E-4 T 30-10-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site CL1_0938 354a32d33131d6b65b0f3b83e767b87c 507 Hamap MF_01463_A Protein translocase subunit SecD [secD]. 6 506 19.028 T 30-10-2018 IPR024912 Protein translocase subunit SecD, archaeal CL1_0938 354a32d33131d6b65b0f3b83e767b87c 507 Gene3D G3DSA:3.30.70.3400 35 118 9.6E-9 T 30-10-2018 CL1_0938 354a32d33131d6b65b0f3b83e767b87c 507 SUPERFAMILY SSF82866 297 492 9.94E-27 T 30-10-2018 CL1_0093 fae32b1617f6418b2e93aa79d0a52076 62 SUPERFAMILY SSF57829 1 56 6.04E-19 T 30-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 CL1_0093 fae32b1617f6418b2e93aa79d0a52076 62 Pfam PF01907 Ribosomal protein L37e 3 56 2.8E-21 T 30-10-2018 IPR001569 Ribosomal protein L37e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0093 fae32b1617f6418b2e93aa79d0a52076 62 ProDom PD005132 RIBOSOMAL RRNA-BINDING METAL-BINDING RNA-BINDING ZINC RIBONUCLEOPROTEIN ZINC-FINGER L37 60S L37E 9 51 6.0E-16 T 30-10-2018 IPR001569 Ribosomal protein L37e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0093 fae32b1617f6418b2e93aa79d0a52076 62 Hamap MF_00547 50S ribosomal protein L37e [rpl37e]. 2 55 20.469 T 30-10-2018 IPR001569 Ribosomal protein L37e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0093 fae32b1617f6418b2e93aa79d0a52076 62 Gene3D G3DSA:2.20.25.30 1 57 6.9E-20 T 30-10-2018 IPR011331 Ribosomal protein L37ae/L37e GO:0003735|GO:0005622|GO:0005840|GO:0006412 CL1_0093 fae32b1617f6418b2e93aa79d0a52076 62 ProSitePatterns PS01077 Ribosomal protein L37e signature. 4 24 - T 30-10-2018 IPR018267 Ribosomal protein L37e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0591 2dbcde1b62a32d1601a2e7ef68a985f4 142 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 1 132 20.446 T 30-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CL1_0591 2dbcde1b62a32d1601a2e7ef68a985f4 142 Pfam PF00572 Ribosomal protein L13 3 102 4.7E-11 T 30-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CL1_0591 2dbcde1b62a32d1601a2e7ef68a985f4 142 PIRSF PIRSF002181 1 142 5.1E-43 T 30-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CL1_0591 2dbcde1b62a32d1601a2e7ef68a985f4 142 TIGRFAM TIGR01077 L13_A_E: ribosomal protein uL13 3 142 1.1E-64 T 30-10-2018 IPR005755 Ribosomal protein L13, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 CL1_0591 2dbcde1b62a32d1601a2e7ef68a985f4 142 Gene3D G3DSA:3.90.1180.10 1 142 2.5E-57 T 30-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 CL1_0591 2dbcde1b62a32d1601a2e7ef68a985f4 142 ProSitePatterns PS00783 Ribosomal protein L13 signature. 79 102 - T 30-10-2018 IPR023563 Ribosomal protein L13, conserved site GO:0003735|GO:0005840|GO:0006412 CL1_0591 2dbcde1b62a32d1601a2e7ef68a985f4 142 SUPERFAMILY SSF52161 2 142 4.97E-44 T 30-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 CL1_0621 efae76798532328126a9b88eadbeba1b 66 ProSitePatterns PS00579 Ribosomal protein L29 signature. 40 54 - T 30-10-2018 IPR018254 Ribosomal protein L29, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0621 efae76798532328126a9b88eadbeba1b 66 Pfam PF00831 Ribosomal L29 protein 4 61 2.3E-17 T 30-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0621 efae76798532328126a9b88eadbeba1b 66 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 1 61 15.647 T 30-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0621 efae76798532328126a9b88eadbeba1b 66 SUPERFAMILY SSF46561 1 61 4.71E-16 T 30-10-2018 IPR036049 Ribosomal protein L29/L35 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0621 efae76798532328126a9b88eadbeba1b 66 Gene3D G3DSA:1.10.287.310 1 66 7.8E-20 T 30-10-2018 CL1_0621 efae76798532328126a9b88eadbeba1b 66 TIGRFAM TIGR00012 L29: ribosomal protein uL29 5 61 2.9E-20 T 30-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_1850 33e0d8e78c1881cb857c961ad9a271e3 118 SUPERFAMILY SSF46785 22 114 4.63E-29 T 30-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CL1_1850 33e0d8e78c1881cb857c961ad9a271e3 118 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 68 83 8.9E-17 T 30-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CL1_1850 33e0d8e78c1881cb857c961ad9a271e3 118 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 55 66 8.9E-17 T 30-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CL1_1850 33e0d8e78c1881cb857c961ad9a271e3 118 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 83 98 8.9E-17 T 30-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CL1_1850 33e0d8e78c1881cb857c961ad9a271e3 118 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 35 50 8.9E-17 T 30-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CL1_1850 33e0d8e78c1881cb857c961ad9a271e3 118 Pfam PF01022 Bacterial regulatory protein, arsR family 40 85 1.1E-16 T 30-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CL1_1850 33e0d8e78c1881cb857c961ad9a271e3 118 ProSitePatterns PS00846 Bacterial regulatory proteins, arsR family signature. 57 75 - T 30-10-2018 IPR018334 ArsR-type transcription regulator, HTH motif GO:0003700|GO:0005622|GO:0006355 CL1_1850 33e0d8e78c1881cb857c961ad9a271e3 118 SMART SM00418 33 112 3.4E-33 T 30-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CL1_1850 33e0d8e78c1881cb857c961ad9a271e3 118 Gene3D G3DSA:1.10.10.10 1 118 3.8E-36 T 30-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CL1_1153 ff50073ae281df449572781a94c35194 424 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 142 162 - T 30-10-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 CL1_1153 ff50073ae281df449572781a94c35194 424 SUPERFAMILY SSF102114 127 363 1.06E-55 T 30-10-2018 CL1_1153 ff50073ae281df449572781a94c35194 424 Gene3D G3DSA:3.40.50.12160 2 123 7.1E-25 T 30-10-2018 IPR038135 Methylthiotransferase, N-terminal domain superfamily CL1_1153 ff50073ae281df449572781a94c35194 424 Pfam PF00919 Uncharacterized protein family UPF0004 3 83 9.0E-22 T 30-10-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 CL1_1153 ff50073ae281df449572781a94c35194 424 Pfam PF04055 Radical SAM superfamily 142 314 9.0E-26 T 30-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CL1_1153 ff50073ae281df449572781a94c35194 424 SMART SM00729 138 355 1.3E-63 T 30-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 CL1_1153 ff50073ae281df449572781a94c35194 424 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 3 421 1.7E-132 T 30-10-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 CL1_1153 ff50073ae281df449572781a94c35194 424 Pfam PF01938 TRAM domain 366 423 1.0E-10 T 30-10-2018 IPR002792 TRAM domain CL1_1153 ff50073ae281df449572781a94c35194 424 Gene3D G3DSA:3.80.30.20 138 369 2.2E-75 T 30-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe CL1_1153 ff50073ae281df449572781a94c35194 424 TIGRFAM TIGR01578 MiaB-like-B: MiaB-like tRNA modifying enzyme, archaeal-type 3 422 4.6E-142 T 30-10-2018 IPR006466 MiaB-like tRNA modifying enzyme, archaeal-type Reactome: R-HSA-6782315 CL1_0091 d44deba6d7035c2cb0688cf4d87b745d 755 Pfam PF00128 Alpha amylase, catalytic domain 337 642 2.3E-63 T 30-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CL1_0091 d44deba6d7035c2cb0688cf4d87b745d 755 Gene3D G3DSA:3.90.400.10 410 463 2.1E-121 T 30-10-2018 CL1_0091 d44deba6d7035c2cb0688cf4d87b745d 755 Pfam PF11941 Domain of unknown function (DUF3459) 665 748 7.4E-5 T 30-10-2018 IPR022567 Glycosyl hydrolase, C-terminal (DUF3459) CL1_0091 d44deba6d7035c2cb0688cf4d87b745d 755 Gene3D G3DSA:2.60.40.10 68 168 8.2E-18 T 30-10-2018 IPR013783 Immunoglobulin-like fold CL1_0091 d44deba6d7035c2cb0688cf4d87b745d 755 SMART SM00642 283 672 6.5E-109 T 30-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CL1_0091 d44deba6d7035c2cb0688cf4d87b745d 755 SUPERFAMILY SSF51445 230 679 3.9E-106 T 30-10-2018 IPR017853 Glycoside hydrolase superfamily CL1_0091 d44deba6d7035c2cb0688cf4d87b745d 755 SUPERFAMILY SSF81296 75 167 8.75E-16 T 30-10-2018 IPR014756 Immunoglobulin E-set CL1_0091 d44deba6d7035c2cb0688cf4d87b745d 755 Gene3D G3DSA:3.20.20.80 279 673 2.1E-121 T 30-10-2018 CL1_0091 d44deba6d7035c2cb0688cf4d87b745d 755 Pfam PF16561 Glycogen recognition site of AMP-activated protein kinase 73 134 4.0E-10 T 30-10-2018 IPR032640 AMP-activated protein kinase, glycogen-binding domain Reactome: R-HSA-1445148|Reactome: R-HSA-1632852|Reactome: R-HSA-2151209|Reactome: R-HSA-380972|Reactome: R-HSA-5628897|Reactome: R-HSA-6804756 CL1_1317 9f45da0d3934b5252c5937d7ca7edeee 308 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 18 29 - T 30-10-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CL1_1317 9f45da0d3934b5252c5937d7ca7edeee 308 Pfam PF06463 Molybdenum Cofactor Synthesis C 180 307 7.0E-22 T 30-10-2018 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CL1_1317 9f45da0d3934b5252c5937d7ca7edeee 308 Gene3D G3DSA:3.20.20.70 1 307 2.0E-76 T 30-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CL1_1317 9f45da0d3934b5252c5937d7ca7edeee 308 TIGRFAM TIGR02668 moaA_archaeal: probable molybdenum cofactor biosynthesis protein A 3 308 1.9E-125 T 30-10-2018 IPR013485 Molybdenum cofactor biosynthesis protein A, archaea GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823 CL1_1317 9f45da0d3934b5252c5937d7ca7edeee 308 Pfam PF13353 4Fe-4S single cluster domain 18 104 1.3E-9 T 30-10-2018 CL1_1317 9f45da0d3934b5252c5937d7ca7edeee 308 SUPERFAMILY SSF102114 3 273 8.5E-68 T 30-10-2018 CL1_1317 9f45da0d3934b5252c5937d7ca7edeee 308 Hamap MF_01225_A GTP 3',8-cyclase [moaA]. 3 308 43.193 T 30-10-2018 IPR013485 Molybdenum cofactor biosynthesis protein A, archaea GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823 CL1_1317 9f45da0d3934b5252c5937d7ca7edeee 308 Pfam PF04055 Radical SAM superfamily 17 172 4.4E-31 T 30-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CL1_1317 9f45da0d3934b5252c5937d7ca7edeee 308 SMART SM00729 12 214 2.9E-14 T 30-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 CL1_0005 58a77da5cc7aa3d066db3f328a004a4b 141 Pfam PF02996 Prefoldin subunit 20 133 9.6E-21 T 30-10-2018 IPR004127 Prefoldin alpha-like CL1_0005 58a77da5cc7aa3d066db3f328a004a4b 141 Hamap MF_00308 Prefoldin subunit alpha [pfdA]. 3 137 14.017 T 30-10-2018 IPR011599 Prefoldin alpha subunit, archaea-type GO:0006457|GO:0016272|GO:0051082 Reactome: R-HSA-389957 CL1_0005 58a77da5cc7aa3d066db3f328a004a4b 141 Gene3D G3DSA:1.10.287.370 9 138 6.6E-32 T 30-10-2018 IPR009053 Prefoldin CL1_0005 58a77da5cc7aa3d066db3f328a004a4b 141 SUPERFAMILY SSF46579 9 137 4.71E-22 T 30-10-2018 CL1_0005 58a77da5cc7aa3d066db3f328a004a4b 141 TIGRFAM TIGR00293 TIGR00293: prefoldin, alpha subunit 9 134 1.2E-23 T 30-10-2018 IPR011599 Prefoldin alpha subunit, archaea-type GO:0006457|GO:0016272|GO:0051082 Reactome: R-HSA-389957 CL1_0259 47204a4c417c3ac854c9a01b3c977c95 362 Pfam PF03435 Saccharopine dehydrogenase NADP binding domain 3 113 1.2E-18 T 30-10-2018 IPR005097 Saccharopine dehydrogenase, NADP binding domain GO:0016491|GO:0055114 CL1_0259 47204a4c417c3ac854c9a01b3c977c95 362 Gene3D G3DSA:3.40.50.720 2 349 1.8E-129 T 30-10-2018 CL1_0259 47204a4c417c3ac854c9a01b3c977c95 362 Gene3D G3DSA:3.30.360.10 118 299 1.8E-129 T 30-10-2018 CL1_0259 47204a4c417c3ac854c9a01b3c977c95 362 SUPERFAMILY SSF51735 1 168 1.36E-22 T 30-10-2018 IPR036291 NAD(P)-binding domain superfamily CL1_0259 47204a4c417c3ac854c9a01b3c977c95 362 SUPERFAMILY SSF55347 118 255 2.81E-39 T 30-10-2018 CL1_0259 47204a4c417c3ac854c9a01b3c977c95 362 Pfam PF16653 Saccharopine dehydrogenase C-terminal domain 117 349 7.0E-28 T 30-10-2018 IPR032095 Saccharopine dehydrogenase, C-terminal Reactome: R-HSA-71064 CL1_0040 4faf1f53c35d7b568f8c497fd3cb7515 310 Pfam PF06849 Protein of unknown function (DUF1246) 4 114 7.2E-32 T 30-10-2018 IPR010672 IMP biosynthesis enzyme PurP, N-terminal GO:0000287|GO:0005524|GO:0006188|GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 CL1_0040 4faf1f53c35d7b568f8c497fd3cb7515 310 Gene3D G3DSA:3.40.50.20 1 83 8.0E-29 T 30-10-2018 CL1_0040 4faf1f53c35d7b568f8c497fd3cb7515 310 Gene3D G3DSA:3.30.470.20 85 308 2.0E-74 T 30-10-2018 CL1_0040 4faf1f53c35d7b568f8c497fd3cb7515 310 SUPERFAMILY SSF56059 99 310 2.12E-66 T 30-10-2018 CL1_0040 4faf1f53c35d7b568f8c497fd3cb7515 310 SUPERFAMILY SSF52440 3 95 2.4E-30 T 30-10-2018 IPR016185 Pre-ATP-grasp domain superfamily CL1_0040 4faf1f53c35d7b568f8c497fd3cb7515 310 Gene3D G3DSA:3.30.1490.20 112 165 2.0E-74 T 30-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 CL1_0040 4faf1f53c35d7b568f8c497fd3cb7515 310 Pfam PF06973 Domain of unknown function (DUF1297) 156 310 6.5E-42 T 30-10-2018 IPR009720 IMP biosynthesis enzyme PurP, C-terminal GO:0000287|GO:0005524|GO:0006188|GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 CL1_0207 ed508ee2aeb1f93cda47f2ef70e8328d 358 Pfam PF00557 Metallopeptidase family M24 149 350 1.1E-27 T 30-10-2018 IPR000994 Peptidase M24 CL1_0207 ed508ee2aeb1f93cda47f2ef70e8328d 358 Gene3D G3DSA:3.40.350.10 8 142 6.6E-20 T 30-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal CL1_0207 ed508ee2aeb1f93cda47f2ef70e8328d 358 Pfam PF01321 Creatinase/Prolidase N-terminal domain 11 142 1.4E-11 T 30-10-2018 IPR000587 Creatinase, N-terminal GO:0016787 CL1_0207 ed508ee2aeb1f93cda47f2ef70e8328d 358 SUPERFAMILY SSF53092 5 141 8.89E-24 T 30-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal CL1_0207 ed508ee2aeb1f93cda47f2ef70e8328d 358 SUPERFAMILY SSF55920 141 358 2.09E-40 T 30-10-2018 IPR036005 Creatinase/aminopeptidase-like CL1_0207 ed508ee2aeb1f93cda47f2ef70e8328d 358 Gene3D G3DSA:3.90.230.10 143 358 2.5E-39 T 30-10-2018 CL1_0777 5ad117dd8c932af5760643988fab1a1b 148 SUPERFAMILY SSF88723 2 131 4.49E-17 T 30-10-2018 IPR029060 PIN-like domain superfamily CL1_0777 5ad117dd8c932af5760643988fab1a1b 148 Pfam PF01850 PIN domain 3 123 3.6E-10 T 30-10-2018 IPR002716 PIN domain CL1_0777 5ad117dd8c932af5760643988fab1a1b 148 Gene3D G3DSA:3.40.50.1010 1 126 7.3E-12 T 30-10-2018 CL1_0409 a3b958b91153a5f87811b1ea2f1035a7 463 Hamap MF_00007 DNA primase DnaG [dnaG]. 36 462 36.4 T 30-10-2018 IPR020607 DNA primase DnaG, archaea GO:0000178|GO:0003896|GO:0008143 CL1_0409 a3b958b91153a5f87811b1ea2f1035a7 463 Gene3D G3DSA:3.40.1360.10 198 294 1.2E-12 T 30-10-2018 CL1_0409 a3b958b91153a5f87811b1ea2f1035a7 463 SMART SM00493 200 269 2.0E-12 T 30-10-2018 IPR006171 TOPRIM domain CL1_0409 a3b958b91153a5f87811b1ea2f1035a7 463 SUPERFAMILY SSF56731 199 311 7.06E-11 T 30-10-2018 CL1_0409 a3b958b91153a5f87811b1ea2f1035a7 463 Pfam PF13662 Toprim domain 201 284 1.4E-12 T 30-10-2018 IPR006171 TOPRIM domain CL1_1836 77024f56893075501079cc9471bfe2cf 159 Gene3D G3DSA:1.20.1260.10 1 143 4.5E-26 T 30-10-2018 IPR012347 Ferritin-like CL1_1836 77024f56893075501079cc9471bfe2cf 159 SUPERFAMILY SSF47240 2 147 2.52E-28 T 30-10-2018 IPR009078 Ferritin-like superfamily CL1_1836 77024f56893075501079cc9471bfe2cf 159 Pfam PF02915 Rubrerythrin 5 138 6.0E-17 T 30-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 CL1_1901 29e1622d5c792b2b1aec17d6f4e494f4 93 TIGRFAM TIGR01687 moaD_arch: MoaD family protein 2 93 2.9E-21 T 30-10-2018 IPR010038 MoaD, archaeal-type CL1_1901 29e1622d5c792b2b1aec17d6f4e494f4 93 Gene3D G3DSA:3.10.20.30 1 93 3.0E-25 T 30-10-2018 IPR012675 Beta-grasp domain superfamily CL1_1901 29e1622d5c792b2b1aec17d6f4e494f4 93 SUPERFAMILY SSF54285 1 93 1.16E-18 T 30-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp CL1_1901 29e1622d5c792b2b1aec17d6f4e494f4 93 Pfam PF02597 ThiS family 3 93 5.2E-17 T 30-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 CL1_0116 3ed3bef81d0363f79a7fd6e2a537f1c9 254 Pfam PF01925 Sulfite exporter TauE/SafE 8 244 2.2E-58 T 30-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 CL1_0510 f95d007ed8de2883d842513a9eb9a0d3 476 Pfam PF01554 MatE 245 406 1.1E-27 T 30-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CL1_0510 f95d007ed8de2883d842513a9eb9a0d3 476 Pfam PF01554 MatE 20 180 8.6E-31 T 30-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CL1_0510 f95d007ed8de2883d842513a9eb9a0d3 476 TIGRFAM TIGR00797 matE: MATE efflux family protein 20 411 3.0E-73 T 30-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CL1_0510 f95d007ed8de2883d842513a9eb9a0d3 476 PIRSF PIRSF006603 1 470 1.2E-153 T 30-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CL1_1639 fbef7cead14f688b692b873963b3ddab 325 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 34 202 7.6E-56 T 30-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CL1_1639 fbef7cead14f688b692b873963b3ddab 325 Gene3D G3DSA:3.40.630.40 22 207 4.6E-65 T 30-10-2018 CL1_1639 fbef7cead14f688b692b873963b3ddab 325 SMART SM00646 92 202 2.4E-38 T 30-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CL1_1639 fbef7cead14f688b692b873963b3ddab 325 Gene3D G3DSA:2.60.40.3500 208 267 1.5E-5 T 30-10-2018 CL1_1639 fbef7cead14f688b692b873963b3ddab 325 SUPERFAMILY SSF53187 32 207 6.59E-60 T 30-10-2018 CL1_0488 164aa9f16b69d0e1ada9d6b1a1a0a063 108 Gene3D G3DSA:3.30.460.10 3 100 3.8E-16 T 30-10-2018 CL1_0488 164aa9f16b69d0e1ada9d6b1a1a0a063 108 SUPERFAMILY SSF81301 2 108 7.64E-20 T 30-10-2018 CL1_0488 164aa9f16b69d0e1ada9d6b1a1a0a063 108 Pfam PF01909 Nucleotidyltransferase domain 13 73 5.1E-13 T 30-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 CL1_1168 dd30f72b2f1050814f75c744c91768bf 75 Gene3D G3DSA:3.30.70.920 1 74 1.5E-26 T 30-10-2018 CL1_1168 dd30f72b2f1050814f75c744c91768bf 75 SUPERFAMILY SSF54909 1 74 1.15E-17 T 30-10-2018 IPR011008 Dimeric alpha-beta barrel CL1_1168 dd30f72b2f1050814f75c744c91768bf 75 Pfam PF01037 Lrp/AsnC ligand binding domain 9 74 5.5E-18 T 30-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CL1_1582 90bd1b7ac7eae77bcaac54b9e6f11a2f 112 SUPERFAMILY SSF46950 8 111 2.62E-28 T 30-10-2018 IPR036883 PDCD5-like superfamily GO:0003677 CL1_1582 90bd1b7ac7eae77bcaac54b9e6f11a2f 112 Pfam PF01984 Double-stranded DNA-binding domain 8 111 2.2E-27 T 30-10-2018 IPR002836 PDCD5-like GO:0003677 CL1_1582 90bd1b7ac7eae77bcaac54b9e6f11a2f 112 PIRSF PIRSF015730 1 112 2.5E-35 T 30-10-2018 IPR002836 PDCD5-like GO:0003677 CL1_1582 90bd1b7ac7eae77bcaac54b9e6f11a2f 112 Hamap MF_00026 DNA-binding protein . 3 112 16.079 T 30-10-2018 IPR022889 DNA-binding protein, archaeal CL1_1582 90bd1b7ac7eae77bcaac54b9e6f11a2f 112 Gene3D G3DSA:1.10.8.140 31 112 6.4E-27 T 30-10-2018 IPR036883 PDCD5-like superfamily GO:0003677 CL1_0658 1274d545eff94adfe6b9d9c304df6bc6 281 SMART SM00116 10 59 5.0E-5 T 30-10-2018 IPR000644 CBS domain CL1_0658 1274d545eff94adfe6b9d9c304df6bc6 281 SMART SM00116 70 118 3.1E-10 T 30-10-2018 IPR000644 CBS domain CL1_0658 1274d545eff94adfe6b9d9c304df6bc6 281 SMART SM00116 231 279 3.5E-10 T 30-10-2018 IPR000644 CBS domain CL1_0658 1274d545eff94adfe6b9d9c304df6bc6 281 SMART SM00116 136 184 3.5 T 30-10-2018 IPR000644 CBS domain CL1_0658 1274d545eff94adfe6b9d9c304df6bc6 281 SUPERFAMILY SSF54631 124 278 1.32E-31 T 30-10-2018 CL1_0658 1274d545eff94adfe6b9d9c304df6bc6 281 Gene3D G3DSA:3.10.580.10 1 122 1.5E-39 T 30-10-2018 CL1_0658 1274d545eff94adfe6b9d9c304df6bc6 281 Gene3D G3DSA:3.10.580.10 123 281 1.9E-36 T 30-10-2018 CL1_0658 1274d545eff94adfe6b9d9c304df6bc6 281 SUPERFAMILY SSF54631 1 117 4.17E-28 T 30-10-2018 CL1_0658 1274d545eff94adfe6b9d9c304df6bc6 281 Pfam PF00571 CBS domain 3 55 1.1E-8 T 30-10-2018 IPR000644 CBS domain CL1_0658 1274d545eff94adfe6b9d9c304df6bc6 281 Pfam PF00571 CBS domain 136 181 1.1E-4 T 30-10-2018 IPR000644 CBS domain CL1_0658 1274d545eff94adfe6b9d9c304df6bc6 281 Pfam PF00571 CBS domain 224 279 4.8E-13 T 30-10-2018 IPR000644 CBS domain CL1_0658 1274d545eff94adfe6b9d9c304df6bc6 281 Pfam PF00571 CBS domain 68 116 2.1E-12 T 30-10-2018 IPR000644 CBS domain CL1_2013 06cf766e6eebfd7657a40819da33e49a 336 SUPERFAMILY SSF52733 18 327 2.88E-41 T 30-10-2018 IPR036087 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like superfamily GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 CL1_2013 06cf766e6eebfd7657a40819da33e49a 336 Gene3D G3DSA:3.40.50.10210 1 333 3.7E-125 T 30-10-2018 CL1_2013 06cf766e6eebfd7657a40819da33e49a 336 Hamap MF_01086 UPF0284 protein . 1 336 136.276 T 30-10-2018 IPR002805 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, putative CL1_2013 06cf766e6eebfd7657a40819da33e49a 336 TIGRFAM TIGR00303 TIGR00303: TIGR00303 family protein 2 323 7.9E-100 T 30-10-2018 IPR002805 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, putative CL1_1532 d65c0cd0dc23d486a7240f885b08180c 189 SUPERFAMILY SSF88697 2 103 1.19E-22 T 30-10-2018 IPR015947 PUA-like superfamily CL1_1532 d65c0cd0dc23d486a7240f885b08180c 189 SMART SM01022 4 104 5.8E-25 T 30-10-2018 IPR007374 ASCH domain CL1_1532 d65c0cd0dc23d486a7240f885b08180c 189 Pfam PF04266 ASCH domain 4 104 2.8E-18 T 30-10-2018 IPR007374 ASCH domain CL1_0393 91f2addd3ab5862921096ea1e5adb54a 769 TIGRFAM TIGR02123 TRAP_fused: TRAP transporter, 4TM/12TM fusion protein 65 740 2.8E-166 T 30-10-2018 IPR011853 TRAP C4-dicarboxylate transport system permease, fused DctM-DctQ CL1_0393 91f2addd3ab5862921096ea1e5adb54a 769 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 146 450 1.4E-55 T 30-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit CL1_0393 91f2addd3ab5862921096ea1e5adb54a 769 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 463 690 1.7E-25 T 30-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit CL1_0538 a07181dad2a0d24913ec6d440a4ded12 648 Pfam PF10996 Beta-Casp domain 433 556 5.2E-25 T 30-10-2018 IPR022712 Beta-Casp domain CL1_0538 a07181dad2a0d24913ec6d440a4ded12 648 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 576 639 1.4E-18 T 30-10-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain CL1_0538 a07181dad2a0d24913ec6d440a4ded12 648 Pfam PF16661 Metallo-beta-lactamase superfamily domain 204 351 4.9E-9 T 30-10-2018 IPR001279 Metallo-beta-lactamase CL1_0538 a07181dad2a0d24913ec6d440a4ded12 648 Gene3D G3DSA:3.40.50.10890 401 588 1.2E-165 T 30-10-2018 CL1_0538 a07181dad2a0d24913ec6d440a4ded12 648 SMART SM01027 433 557 8.3E-58 T 30-10-2018 IPR022712 Beta-Casp domain CL1_0538 a07181dad2a0d24913ec6d440a4ded12 648 SMART SM00322 102 169 4.9E-5 T 30-10-2018 IPR004087 K Homology domain GO:0003676 CL1_0538 a07181dad2a0d24913ec6d440a4ded12 648 SUPERFAMILY SSF56281 183 647 7.27E-133 T 30-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like CL1_0538 a07181dad2a0d24913ec6d440a4ded12 648 Gene3D G3DSA:3.30.300.20 72 142 1.6E-63 T 30-10-2018 IPR015946 K homology domain-like, alpha/beta CL1_0538 a07181dad2a0d24913ec6d440a4ded12 648 Gene3D G3DSA:3.30.300.230 17 176 1.6E-63 T 30-10-2018 CL1_0538 a07181dad2a0d24913ec6d440a4ded12 648 SUPERFAMILY SSF54814 96 141 2.68E-5 T 30-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 CL1_0538 a07181dad2a0d24913ec6d440a4ded12 648 SMART SM00849 198 428 1.4E-25 T 30-10-2018 IPR001279 Metallo-beta-lactamase CL1_0538 a07181dad2a0d24913ec6d440a4ded12 648 TIGRFAM TIGR03675 arCOG00543: arCOG00543 universal archaeal KH-domain/beta-lactamase-domain protein 13 647 1.2E-299 T 30-10-2018 IPR019975 KH-domain/beta-lactamase-domain protein, archaea CL1_0538 a07181dad2a0d24913ec6d440a4ded12 648 Pfam PF17214 KH domain 9 76 5.8E-27 T 30-10-2018 IPR033769 KH domain, archaeal CL1_0538 a07181dad2a0d24913ec6d440a4ded12 648 Gene3D G3DSA:3.60.15.10 191 627 1.2E-165 T 30-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like CL1_0908 81db54c987d9f32bf3618d1216e84f83 135 Hamap MF_00585 UPF0216 protein . 4 135 26.376 T 30-10-2018 IPR002746 Uncharacterised protein family UPF0216 CL1_0908 81db54c987d9f32bf3618d1216e84f83 135 PIRSF PIRSF005264 1 135 8.7E-43 T 30-10-2018 IPR002746 Uncharacterised protein family UPF0216 CL1_0908 81db54c987d9f32bf3618d1216e84f83 135 ProDom PD016056 UPF0216 PYRAB16100 PH0358 MTH949 MK1676 AF0460 PF0452 MJ1224 8 109 5.0E-29 T 30-10-2018 IPR002746 Uncharacterised protein family UPF0216 CL1_0908 81db54c987d9f32bf3618d1216e84f83 135 Pfam PF01886 Protein of unknown function DUF61 6 132 6.3E-33 T 30-10-2018 IPR002746 Uncharacterised protein family UPF0216 CL1_1728 3527d88cd70f24314514e23649da9699 691 Gene3D G3DSA:2.40.128.630 38 142 1.5E-7 T 30-10-2018 CL1_1728 3527d88cd70f24314514e23649da9699 691 TIGRFAM TIGR04288 CGP_CTERM: CGP-CTERM domain 669 688 6.9E-5 T 30-10-2018 IPR027552 CGP-CTERM domain CL1_1728 3527d88cd70f24314514e23649da9699 691 Pfam PF13360 PQQ-like domain 53 221 2.2E-7 T 30-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat CL1_1728 3527d88cd70f24314514e23649da9699 691 SMART SM00320 16 58 3.8 T 30-10-2018 IPR001680 WD40 repeat GO:0005515 CL1_1728 3527d88cd70f24314514e23649da9699 691 SMART SM00320 231 266 9.3 T 30-10-2018 IPR001680 WD40 repeat GO:0005515 CL1_1728 3527d88cd70f24314514e23649da9699 691 SMART SM00320 190 227 21.0 T 30-10-2018 IPR001680 WD40 repeat GO:0005515 CL1_1728 3527d88cd70f24314514e23649da9699 691 Pfam PF08308 PEGA domain 346 412 1.7E-18 T 30-10-2018 IPR013229 PEGA CL1_1728 3527d88cd70f24314514e23649da9699 691 Gene3D G3DSA:2.60.40.1120 342 412 5.2E-5 T 30-10-2018 CL1_1728 3527d88cd70f24314514e23649da9699 691 SMART SM00564 76 108 9.6 T 30-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat CL1_1728 3527d88cd70f24314514e23649da9699 691 SMART SM00564 254 285 170.0 T 30-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat CL1_1728 3527d88cd70f24314514e23649da9699 691 SMART SM00564 37 68 86.0 T 30-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat CL1_1728 3527d88cd70f24314514e23649da9699 691 Gene3D G3DSA:2.130.10.10 184 336 4.8E-8 T 30-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 CL1_1728 3527d88cd70f24314514e23649da9699 691 SUPERFAMILY SSF50969 31 317 7.3E-26 T 30-10-2018 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like CL1_0028 4e20f76cc47706213678ca7b30b94a8e 215 Pfam PF00156 Phosphoribosyl transferase domain 16 152 5.9E-23 T 30-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CL1_0028 4e20f76cc47706213678ca7b30b94a8e 215 Gene3D G3DSA:3.40.50.2020 6 177 1.2E-43 T 30-10-2018 CL1_0028 4e20f76cc47706213678ca7b30b94a8e 215 SUPERFAMILY SSF53271 7 161 4.33E-39 T 30-10-2018 IPR029057 Phosphoribosyltransferase-like CL1_1543 508195c43509c9d5c78bc73393b20090 270 SUPERFAMILY SSF55729 1 136 1.5E-24 T 30-10-2018 IPR016181 Acyl-CoA N-acyltransferase CL1_1543 508195c43509c9d5c78bc73393b20090 270 Pfam PF00583 Acetyltransferase (GNAT) family 27 126 3.6E-16 T 30-10-2018 IPR000182 GNAT domain CL1_1543 508195c43509c9d5c78bc73393b20090 270 Gene3D G3DSA:3.40.630.30 2 189 1.1E-34 T 30-10-2018 CL1_0280 d43c81c08ccb212dc1cdbbf24bf8a05f 272 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 46 73 - T 30-10-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 CL1_0280 d43c81c08ccb212dc1cdbbf24bf8a05f 272 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 14 267 46.445 T 30-10-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 CL1_0280 d43c81c08ccb212dc1cdbbf24bf8a05f 272 Gene3D G3DSA:3.40.50.150 2 193 1.1E-64 T 30-10-2018 CL1_0280 d43c81c08ccb212dc1cdbbf24bf8a05f 272 SUPERFAMILY SSF53335 12 268 1.01E-62 T 30-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CL1_0280 d43c81c08ccb212dc1cdbbf24bf8a05f 272 Pfam PF00398 Ribosomal RNA adenine dimethylase 14 225 2.3E-52 T 30-10-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm CL1_0280 d43c81c08ccb212dc1cdbbf24bf8a05f 272 Gene3D G3DSA:1.10.8.100 195 271 5.3E-7 T 30-10-2018 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201|Reactome: R-HSA-6793080 CL1_0280 d43c81c08ccb212dc1cdbbf24bf8a05f 272 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 15 266 1.0E-76 T 30-10-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 CL1_0280 d43c81c08ccb212dc1cdbbf24bf8a05f 272 SMART SM00650 30 193 1.9E-79 T 30-10-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 CL1_1147 0ab57fffdd527701ae870af7f7aa44fa 156 Pfam PF13247 4Fe-4S dicluster domain 39 127 6.4E-24 T 30-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CL1_1147 0ab57fffdd527701ae870af7f7aa44fa 156 Pfam PF12800 4Fe-4S binding domain 10 22 0.051 T 30-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CL1_1147 0ab57fffdd527701ae870af7f7aa44fa 156 Gene3D G3DSA:3.30.70.20 35 153 1.6E-33 T 30-10-2018 CL1_1147 0ab57fffdd527701ae870af7f7aa44fa 156 Gene3D G3DSA:3.30.70.20 2 34 2.6E-5 T 30-10-2018 CL1_1147 0ab57fffdd527701ae870af7f7aa44fa 156 SUPERFAMILY SSF54862 3 132 1.15E-48 T 30-10-2018 CL1_1147 0ab57fffdd527701ae870af7f7aa44fa 156 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 76 87 - T 30-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CL1_0686 9d8a8375367eb4a34c3e06dbc92f3e90 127 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 19 111 5.7E-11 T 30-10-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 CL1_0686 9d8a8375367eb4a34c3e06dbc92f3e90 127 SUPERFAMILY SSF54637 13 118 1.19E-27 T 30-10-2018 IPR029069 HotDog domain superfamily CL1_0686 9d8a8375367eb4a34c3e06dbc92f3e90 127 Pfam PF03061 Thioesterase superfamily 40 111 2.1E-9 T 30-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 CL1_0686 9d8a8375367eb4a34c3e06dbc92f3e90 127 Gene3D G3DSA:3.10.129.10 1 127 4.8E-45 T 30-10-2018 CL1_0627 39f1b26ead1e16fee501c7a55f1fa1db 255 TIGRFAM TIGR03672 rpl4p_arch: 50S ribosomal protein uL4 1 252 2.5E-117 T 30-10-2018 IPR019970 Ribosomal protein L4 GO:0003735|GO:0005840|GO:0006412|GO:0019843 CL1_0627 39f1b26ead1e16fee501c7a55f1fa1db 255 Hamap MF_01328_A 50S ribosomal protein L4 [rplD]. 2 253 44.756 T 30-10-2018 IPR019970 Ribosomal protein L4 GO:0003735|GO:0005840|GO:0006412|GO:0019843 CL1_0627 39f1b26ead1e16fee501c7a55f1fa1db 255 Gene3D G3DSA:3.40.1370.10 1 255 2.7E-100 T 30-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 CL1_0627 39f1b26ead1e16fee501c7a55f1fa1db 255 Pfam PF00573 Ribosomal protein L4/L1 family 16 252 7.9E-50 T 30-10-2018 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 CL1_0627 39f1b26ead1e16fee501c7a55f1fa1db 255 SUPERFAMILY SSF52166 1 252 1.96E-73 T 30-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 CL1_0627 39f1b26ead1e16fee501c7a55f1fa1db 255 ProSitePatterns PS00939 Ribosomal protein L1e signature. 106 132 - T 30-10-2018 IPR013000 Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_1433 2018f00c8bc5ccd8cdb1bf7d6080bec1 100 TIGRFAM TIGR01300 CPA3_mnhG_phaG: monovalent cation/proton antiporter, MnhG/PhaG subunit 1 95 1.4E-28 T 30-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 CL1_1433 2018f00c8bc5ccd8cdb1bf7d6080bec1 100 Pfam PF03334 Na+/H+ antiporter subunit 2 82 4.5E-21 T 30-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 CL1_0592 4991b7be35080652696cb101f05ac384 121 ProSitePatterns PS01106 Ribosomal protein L18e signature. 36 53 - T 30-10-2018 IPR021132 Ribosomal protein L18e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0592 4991b7be35080652696cb101f05ac384 121 Hamap MF_00329 50S ribosomal protein L18e [rpl18e]. 5 121 31.047 T 30-10-2018 IPR022947 Ribosomal protein L18e, archaea CL1_0592 4991b7be35080652696cb101f05ac384 121 Gene3D G3DSA:3.100.10.10 6 121 6.7E-42 T 30-10-2018 CL1_0592 4991b7be35080652696cb101f05ac384 121 SUPERFAMILY SSF52080 6 120 4.06E-31 T 30-10-2018 IPR036227 Ribosomal L18e/L15P superfamily CL1_0592 4991b7be35080652696cb101f05ac384 121 Pfam PF17135 Ribosomal protein 60S L18 and 50S L18e 12 120 6.1E-17 T 30-10-2018 IPR021131 Ribosomal protein L18e/L15P CL1_1610 48027d30b78781a6661d3b709fe0ce13 319 Gene3D G3DSA:1.20.5.170 1 42 3.9E-5 T 30-10-2018 CL1_1610 48027d30b78781a6661d3b709fe0ce13 319 TIGRFAM TIGR00750 lao: LAO/AO transport system ATPase 12 312 7.7E-127 T 30-10-2018 IPR005129 SIMIBI class G3E GTPase, ArgK/MeaB GO:0003924|GO:0005525 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CL1_1610 48027d30b78781a6661d3b709fe0ce13 319 Pfam PF03308 ArgK protein 18 280 9.0E-102 T 30-10-2018 CL1_1610 48027d30b78781a6661d3b709fe0ce13 319 SUPERFAMILY SSF52540 2 308 1.26E-80 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_1610 48027d30b78781a6661d3b709fe0ce13 319 Gene3D G3DSA:3.40.50.300 43 251 1.5E-87 T 30-10-2018 CL1_1610 48027d30b78781a6661d3b709fe0ce13 319 SMART SM00382 44 194 1.4E-4 T 30-10-2018 IPR003593 AAA+ ATPase domain CL1_1881 7316fb547200a626726a7c6d2e59e850 88 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 9 87 1.3E-7 T 30-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family CL1_1881 7316fb547200a626726a7c6d2e59e850 88 SUPERFAMILY SSF143011 1 86 3.79E-22 T 30-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily CL1_1881 7316fb547200a626726a7c6d2e59e850 88 Gene3D G3DSA:3.30.2310.20 1 88 5.6E-27 T 30-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily CL1_1539 d6dcee5e0e0a2e859578c64f073d088e 187 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 4 63 1.8E-18 T 30-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CL1_1539 d6dcee5e0e0a2e859578c64f073d088e 187 SUPERFAMILY SSF52374 3 166 8.3E-37 T 30-10-2018 CL1_1539 d6dcee5e0e0a2e859578c64f073d088e 187 Hamap MF_00243 Nicotinamide-nucleotide adenylyltransferase. 1 187 89.973 T 30-10-2018 IPR006418 Nicotinamide-nucleotide adenylyltransferase, archaeal type GO:0000309|GO:0005737|GO:0009435 KEGG: 00760+2.7.7.1 CL1_1539 d6dcee5e0e0a2e859578c64f073d088e 187 Pfam PF01467 Cytidylyltransferase-like 6 136 1.3E-18 T 30-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CL1_1539 d6dcee5e0e0a2e859578c64f073d088e 187 TIGRFAM TIGR01527 arch_NMN_Atrans: nicotinamide-nucleotide adenylyltransferase 4 168 1.8E-68 T 30-10-2018 IPR006418 Nicotinamide-nucleotide adenylyltransferase, archaeal type GO:0000309|GO:0005737|GO:0009435 KEGG: 00760+2.7.7.1 CL1_1539 d6dcee5e0e0a2e859578c64f073d088e 187 Gene3D G3DSA:3.40.50.620 1 178 4.1E-54 T 30-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CL1_1126 488cb3e007ffb89b054fa151b96f9fe9 160 Pfam PF02926 THUMP domain 26 148 1.2E-22 T 30-10-2018 IPR004114 THUMP domain GO:0003723 CL1_1126 488cb3e007ffb89b054fa151b96f9fe9 160 SMART SM00981 62 149 4.4E-13 T 30-10-2018 IPR004114 THUMP domain GO:0003723 CL1_1126 488cb3e007ffb89b054fa151b96f9fe9 160 SUPERFAMILY SSF143437 34 148 4.71E-16 T 30-10-2018 CL1_1126 488cb3e007ffb89b054fa151b96f9fe9 160 Gene3D G3DSA:3.30.2130.30 1 150 5.8E-14 T 30-10-2018 CL1_1502 34a558e99058d7fc397e328c873a0f46 366 Gene3D G3DSA:3.40.50.150 172 352 6.9E-27 T 30-10-2018 CL1_1502 34a558e99058d7fc397e328c873a0f46 366 SUPERFAMILY SSF53335 173 339 2.57E-22 T 30-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CL1_1502 34a558e99058d7fc397e328c873a0f46 366 Pfam PF01170 Putative RNA methylase family UPF0020 175 321 1.3E-12 T 30-10-2018 IPR000241 Putative RNA methylase domain CL1_1880 402040e609d38c3ea4dc6ef83167a940 472 Pfam PF01523 Putative modulator of DNA gyrase 18 324 5.1E-58 T 30-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 CL1_1880 402040e609d38c3ea4dc6ef83167a940 472 Gene3D G3DSA:3.30.2290.10 1 194 1.0E-25 T 30-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal CL1_1880 402040e609d38c3ea4dc6ef83167a940 472 SUPERFAMILY SSF111283 2 467 3.14E-103 T 30-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 CL1_1880 402040e609d38c3ea4dc6ef83167a940 472 PIRSF PIRSF004919 1 471 5.5E-152 T 30-10-2018 IPR025502 TldD CL1_1701 826c9e1e9c58949093fee7b6f9dfcaf0 116 Pfam PF01850 PIN domain 11 95 1.4E-5 T 30-10-2018 IPR002716 PIN domain CL1_1701 826c9e1e9c58949093fee7b6f9dfcaf0 116 SUPERFAMILY SSF88723 5 98 1.18E-14 T 30-10-2018 IPR029060 PIN-like domain superfamily CL1_1701 826c9e1e9c58949093fee7b6f9dfcaf0 116 Gene3D G3DSA:3.40.50.1010 1 111 2.1E-11 T 30-10-2018 CL1_0452 996845125dfe703e412cf16a5c935b52 417 Pfam PF01385 Probable transposase 167 282 5.1E-29 T 30-10-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 CL1_0452 996845125dfe703e412cf16a5c935b52 417 Pfam PF07282 Putative transposase DNA-binding domain 301 375 4.2E-10 T 30-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal CL1_0452 996845125dfe703e412cf16a5c935b52 417 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 248 328 1.1E-24 T 30-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal CL1_0107 f20e27488ba2c00c3cd6ab04dba40363 658 Gene3D G3DSA:3.40.50.300 2 184 3.2E-48 T 30-10-2018 CL1_0107 f20e27488ba2c00c3cd6ab04dba40363 658 SUPERFAMILY SSF52540 5 173 2.22E-43 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_0107 f20e27488ba2c00c3cd6ab04dba40363 658 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 26 44 8.4E-7 T 30-10-2018 IPR006073 GTP binding domain GO:0005525 CL1_0107 f20e27488ba2c00c3cd6ab04dba40363 658 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 8.4E-7 T 30-10-2018 IPR006073 GTP binding domain GO:0005525 CL1_0107 f20e27488ba2c00c3cd6ab04dba40363 658 Pfam PF07664 Ferrous iron transport protein B C terminus 457 509 9.1E-18 T 30-10-2018 IPR011640 Ferrous iron transport protein B, C-terminal GO:0015093|GO:0015684|GO:0016021 CL1_0107 f20e27488ba2c00c3cd6ab04dba40363 658 Pfam PF07670 Nucleoside recognition 514 628 6.2E-28 T 30-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 CL1_0107 f20e27488ba2c00c3cd6ab04dba40363 658 Pfam PF07670 Nucleoside recognition 353 447 9.9E-13 T 30-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 CL1_0107 f20e27488ba2c00c3cd6ab04dba40363 658 TIGRFAM TIGR00437 feoB: ferrous iron transport protein B 9 625 5.4E-192 T 30-10-2018 IPR003373 Ferrous iron transport protein B GO:0005525|GO:0015093|GO:0015684|GO:0016021 CL1_0107 f20e27488ba2c00c3cd6ab04dba40363 658 Pfam PF02421 Ferrous iron transport protein B 4 159 6.7E-65 T 30-10-2018 IPR030389 FeoB-type guanine nucleotide-binding (G) domain GO:0005525 CL1_1265 fe6bd6f1a0c248a0758ed1add767fb4f 368 SUPERFAMILY SSF53187 4 367 3.55E-57 T 30-10-2018 CL1_1265 fe6bd6f1a0c248a0758ed1add767fb4f 368 SUPERFAMILY SSF55031 167 267 2.84E-13 T 30-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain CL1_1265 fe6bd6f1a0c248a0758ed1add767fb4f 368 Pfam PF01546 Peptidase family M20/M25/M40 61 365 1.5E-29 T 30-10-2018 IPR002933 Peptidase M20 GO:0016787 CL1_1265 fe6bd6f1a0c248a0758ed1add767fb4f 368 Gene3D G3DSA:3.40.630.10 5 356 3.7E-76 T 30-10-2018 CL1_1265 fe6bd6f1a0c248a0758ed1add767fb4f 368 Pfam PF07687 Peptidase dimerisation domain 164 267 4.3E-12 T 30-10-2018 IPR011650 Peptidase M20, dimerisation domain CL1_1265 fe6bd6f1a0c248a0758ed1add767fb4f 368 Gene3D G3DSA:3.30.70.360 167 278 3.7E-76 T 30-10-2018 CL1_1265 fe6bd6f1a0c248a0758ed1add767fb4f 368 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 93 131 - T 30-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 CL1_0419 6bd7c7db1312e68f94c114e03991453f 440 Pfam PF13347 MFS/sugar transport protein 44 401 9.6E-13 T 30-10-2018 CL1_0419 6bd7c7db1312e68f94c114e03991453f 440 Gene3D G3DSA:1.20.1250.20 5 224 2.2E-13 T 30-10-2018 CL1_0419 6bd7c7db1312e68f94c114e03991453f 440 SUPERFAMILY SSF103473 9 429 4.19E-40 T 30-10-2018 IPR036259 MFS transporter superfamily CL1_0419 6bd7c7db1312e68f94c114e03991453f 440 Gene3D G3DSA:1.20.1250.20 232 432 5.1E-20 T 30-10-2018 CL1_1063 62bf897fd1a763afaaa682d51d15707f 159 SMART SM00255 4 129 0.0055 T 30-10-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 CL1_1063 62bf897fd1a763afaaa682d51d15707f 159 SUPERFAMILY SSF52200 6 120 1.44E-19 T 30-10-2018 IPR035897 Toll/interleukin-1 receptor homology (TIR) domain superfamily CL1_1063 62bf897fd1a763afaaa682d51d15707f 159 Pfam PF13676 TIR domain 7 108 8.1E-22 T 30-10-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 CL1_1063 62bf897fd1a763afaaa682d51d15707f 159 Gene3D G3DSA:3.40.50.10140 3 137 4.2E-21 T 30-10-2018 IPR035897 Toll/interleukin-1 receptor homology (TIR) domain superfamily CL1_0512 49654a59b922b3c12122d9d31885953e 292 Pfam PF16795 Archaeal phage integrase 86 281 8.6E-13 T 30-10-2018 IPR031857 Integrase SSV1, C-terminal CL1_0512 49654a59b922b3c12122d9d31885953e 292 Gene3D G3DSA:1.10.443.10 82 286 1.4E-31 T 30-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 CL1_1677 0c370127bde79e4bc03a71250243ca1f 254 PRINTS PR00164 ABC-2 type transport system membrane protein signature 175 194 1.2E-16 T 30-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 CL1_1677 0c370127bde79e4bc03a71250243ca1f 254 PRINTS PR00164 ABC-2 type transport system membrane protein signature 195 214 1.2E-16 T 30-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 CL1_1677 0c370127bde79e4bc03a71250243ca1f 254 PRINTS PR00164 ABC-2 type transport system membrane protein signature 138 162 1.2E-16 T 30-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 CL1_1677 0c370127bde79e4bc03a71250243ca1f 254 PRINTS PR00164 ABC-2 type transport system membrane protein signature 101 126 1.2E-16 T 30-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 CL1_1677 0c370127bde79e4bc03a71250243ca1f 254 PRINTS PR00164 ABC-2 type transport system membrane protein signature 22 43 1.2E-16 T 30-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 CL1_1677 0c370127bde79e4bc03a71250243ca1f 254 PIRSF PIRSF006648 1 253 9.0E-71 T 30-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 CL1_1677 0c370127bde79e4bc03a71250243ca1f 254 TIGRFAM TIGR01247 drrB: daunorubicin resistance ABC transporter membrane protein 10 248 4.4E-118 T 30-10-2018 IPR005942 Daunorubicin resistance ABC transporter membrane protein CL1_1677 0c370127bde79e4bc03a71250243ca1f 254 Pfam PF01061 ABC-2 type transporter 3 216 1.7E-44 T 30-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 CL1_0983 a871a53091fc171d2a31592d49ca55d8 64 Pfam PF01954 Protein of unknown function DUF104 1 56 9.5E-15 T 30-10-2018 IPR008203 Uncharacterised protein family UPF0165 CL1_0983 a871a53091fc171d2a31592d49ca55d8 64 Gene3D G3DSA:4.10.1150.10 1 62 1.4E-12 T 30-10-2018 IPR024069 AF2212-like domain superfamily CL1_0983 a871a53091fc171d2a31592d49ca55d8 64 SUPERFAMILY SSF141694 2 57 7.06E-12 T 30-10-2018 CL1_0635 fabdbe0d6e289c5fcd2639124529057f 193 SUPERFAMILY SSF52540 9 128 1.16E-10 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_0635 fabdbe0d6e289c5fcd2639124529057f 193 Pfam PF00437 Type II/IV secretion system protein 7 111 7.5E-7 T 30-10-2018 IPR001482 Type II/IV secretion system protein CL1_0635 fabdbe0d6e289c5fcd2639124529057f 193 Gene3D G3DSA:3.40.50.300 5 190 1.7E-14 T 30-10-2018 CL1_0838 1f95c4cca35bf29a560930474b0ea5eb 509 Pfam PF01943 Polysaccharide biosynthesis protein 12 278 2.2E-30 T 30-10-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 CL1_0838 1f95c4cca35bf29a560930474b0ea5eb 509 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 342 475 1.3E-20 T 30-10-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain CL1_0275 4e445d64ea1ba441d62202edbddb08b7 274 ProDom PD039347 PF1398 MJ0538 PH1392 4 253 4.0E-48 T 30-10-2018 IPR020292 Uncharacterised protein family MJ0538 CL1_1902 7fe1a4e80ad0e7c506d2a99952bd528b 93 TIGRFAM TIGR00106 TIGR00106: uncharacterized protein, MTH1187 family 3 92 4.4E-29 T 30-10-2018 IPR002767 Thiamine-binding protein CL1_1902 7fe1a4e80ad0e7c506d2a99952bd528b 93 Gene3D G3DSA:3.30.70.930 1 93 2.2E-34 T 30-10-2018 IPR029756 MTH1187/YkoF-like CL1_1902 7fe1a4e80ad0e7c506d2a99952bd528b 93 Pfam PF01910 Thiamine-binding protein 4 92 2.0E-31 T 30-10-2018 IPR002767 Thiamine-binding protein CL1_1902 7fe1a4e80ad0e7c506d2a99952bd528b 93 SUPERFAMILY SSF89957 1 92 9.68E-31 T 30-10-2018 IPR029756 MTH1187/YkoF-like CL1_0385 565c42968ae3802f7eb3b441d9430c1c 226 TIGRFAM TIGR02187 GlrX_arch: glutaredoxin-like domain protein 4 223 5.6E-87 T 30-10-2018 IPR011903 Glutaredoxin-like domain CL1_0385 565c42968ae3802f7eb3b441d9430c1c 226 SUPERFAMILY SSF52833 121 221 1.4E-20 T 30-10-2018 IPR036249 Thioredoxin-like superfamily CL1_0385 565c42968ae3802f7eb3b441d9430c1c 226 Pfam PF13192 Thioredoxin domain 137 222 6.3E-15 T 30-10-2018 IPR012336 Thioredoxin-like fold CL1_0385 565c42968ae3802f7eb3b441d9430c1c 226 SUPERFAMILY SSF52833 5 117 3.71E-25 T 30-10-2018 IPR036249 Thioredoxin-like superfamily CL1_0385 565c42968ae3802f7eb3b441d9430c1c 226 Gene3D G3DSA:3.40.30.10 1 117 6.3E-36 T 30-10-2018 CL1_0385 565c42968ae3802f7eb3b441d9430c1c 226 Gene3D G3DSA:3.40.30.10 120 225 1.1E-26 T 30-10-2018 CL1_0125 616b0892e124ae939f83a96fa3a94076 179 Gene3D G3DSA:3.40.50.300 1 179 1.5E-58 T 30-10-2018 CL1_0125 616b0892e124ae939f83a96fa3a94076 179 Pfam PF13238 AAA domain 3 116 1.7E-23 T 30-10-2018 CL1_0125 616b0892e124ae939f83a96fa3a94076 179 SUPERFAMILY SSF52540 1 154 2.96E-25 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_0125 616b0892e124ae939f83a96fa3a94076 179 Hamap MF_00039 Putative adenylate kinase. 1 160 26.007 T 30-10-2018 IPR020618 Adenylate kinase isoenzyme 6 GO:0004017|GO:0005524 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CL1_1344 73fec713e6d641fd4d8612ae876469be 178 PIRSF PIRSF006019 12 169 6.3E-57 T 30-10-2018 IPR016473 Deoxycytidylate deaminase GO:0004132|GO:0006220|GO:0008270 KEGG: 00240+3.5.4.12|MetaCyc: PWY-7210|Reactome: R-HSA-499943 CL1_1344 73fec713e6d641fd4d8612ae876469be 178 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 21 132 2.9E-29 T 30-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain CL1_1344 73fec713e6d641fd4d8612ae876469be 178 Gene3D G3DSA:3.40.140.10 18 166 2.7E-48 T 30-10-2018 CL1_1344 73fec713e6d641fd4d8612ae876469be 178 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 86 121 - T 30-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 CL1_1344 73fec713e6d641fd4d8612ae876469be 178 SUPERFAMILY SSF53927 22 146 4.43E-40 T 30-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 CL1_0767 5e0f1952e9589565b836a56e46a0a6b2 369 ProSitePatterns PS00227 Tubulin subunits alpha, beta, and gamma signature. 101 107 - T 30-10-2018 IPR017975 Tubulin, conserved site GO:0005525|GO:0005874|GO:0007017 Reactome: R-HSA-380320 CL1_0767 5e0f1952e9589565b836a56e46a0a6b2 369 SMART SM00864 2 199 1.6E-32 T 30-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CL1_0767 5e0f1952e9589565b836a56e46a0a6b2 369 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 5 168 7.1E-26 T 30-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CL1_0767 5e0f1952e9589565b836a56e46a0a6b2 369 Gene3D G3DSA:3.40.50.1440 2 364 9.7E-86 T 30-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 CL1_0767 5e0f1952e9589565b836a56e46a0a6b2 369 SUPERFAMILY SSF52490 2 199 6.8E-41 T 30-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 CL1_0767 5e0f1952e9589565b836a56e46a0a6b2 369 PRINTS PR00423 Cell division protein FtsZ signature 93 113 5.6E-10 T 30-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CL1_0767 5e0f1952e9589565b836a56e46a0a6b2 369 PRINTS PR00423 Cell division protein FtsZ signature 123 144 5.6E-10 T 30-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CL1_0767 5e0f1952e9589565b836a56e46a0a6b2 369 PRINTS PR00423 Cell division protein FtsZ signature 183 205 5.6E-10 T 30-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CL1_0767 5e0f1952e9589565b836a56e46a0a6b2 369 Hamap MF_01946 Tubulin-like protein CetZ [cetZ]. 1 354 26.592 T 30-10-2018 IPR032907 Tubulin-like protein CetZ GO:0008360 CL1_0919 d298c01f3ea630c939c340a235cbb4a1 233 Gene3D G3DSA:3.40.50.80 85 196 4.1E-28 T 30-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain CL1_0919 d298c01f3ea630c939c340a235cbb4a1 233 Hamap MF_01211 Dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit [pyrK]. 2 231 33.138 T 30-10-2018 IPR023455 Dihydroorotate dehydrogenase electron transfer subunit CL1_0919 d298c01f3ea630c939c340a235cbb4a1 233 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 197 229 1.7E-10 T 30-10-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain CL1_0919 d298c01f3ea630c939c340a235cbb4a1 233 PIRSF PIRSF006816 1 232 3.6E-74 T 30-10-2018 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 CL1_0919 d298c01f3ea630c939c340a235cbb4a1 233 PRINTS PR00409 Phthalate dioxygenase reductase family signature 118 127 2.0E-5 T 30-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 CL1_0919 d298c01f3ea630c939c340a235cbb4a1 233 PRINTS PR00409 Phthalate dioxygenase reductase family signature 170 178 2.0E-5 T 30-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 CL1_0919 d298c01f3ea630c939c340a235cbb4a1 233 PRINTS PR00409 Phthalate dioxygenase reductase family signature 93 112 2.0E-5 T 30-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 CL1_0919 d298c01f3ea630c939c340a235cbb4a1 233 SUPERFAMILY SSF63380 4 85 1.27E-16 T 30-10-2018 IPR017938 Riboflavin synthase-like beta-barrel CL1_0919 d298c01f3ea630c939c340a235cbb4a1 233 SUPERFAMILY SSF52343 80 228 3.01E-33 T 30-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain CL1_0919 d298c01f3ea630c939c340a235cbb4a1 233 Pfam PF00175 Oxidoreductase NAD-binding domain 94 183 5.3E-8 T 30-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 CL1_0919 d298c01f3ea630c939c340a235cbb4a1 233 Gene3D G3DSA:2.40.30.10 3 83 1.0E-10 T 30-10-2018 CL1_1871 be5d87561a48df57c32233ec556df7ce 251 SUPERFAMILY SSF52467 2 246 5.82E-89 T 30-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily CL1_1871 be5d87561a48df57c32233ec556df7ce 251 Gene3D G3DSA:3.30.1600.10 29 168 4.9E-91 T 30-10-2018 IPR026591 Sirtuin, catalytic core small domain superfamily CL1_1871 be5d87561a48df57c32233ec556df7ce 251 Gene3D G3DSA:3.40.50.1220 12 242 4.9E-91 T 30-10-2018 CL1_1871 be5d87561a48df57c32233ec556df7ce 251 Hamap MF_01121 NAD-dependent protein deacylase [cobB]. 13 248 60.031 T 30-10-2018 IPR027546 Sirtuin, class III GO:0036054|GO:0036055|GO:0070403 Reactome: R-HSA-2151201 CL1_1871 be5d87561a48df57c32233ec556df7ce 251 Pfam PF02146 Sir2 family 20 198 1.4E-56 T 30-10-2018 IPR003000 Sirtuin family GO:0070403 CL1_0090 31cb7e6cba4cc6028f5fa19651da0b18 570 Gene3D G3DSA:3.30.930.10 14 458 1.1E-141 T 30-10-2018 CL1_0090 31cb7e6cba4cc6028f5fa19651da0b18 570 SUPERFAMILY SSF55681 7 478 3.78E-117 T 30-10-2018 CL1_0090 31cb7e6cba4cc6028f5fa19651da0b18 570 SUPERFAMILY SSF52954 462 567 3.62E-32 T 30-10-2018 CL1_0090 31cb7e6cba4cc6028f5fa19651da0b18 570 Pfam PF03129 Anticodon binding domain 475 565 6.9E-23 T 30-10-2018 IPR004154 Anticodon-binding CL1_0090 31cb7e6cba4cc6028f5fa19651da0b18 570 PRINTS PR01043 Glycyl-tRNA synthetase signature 27 41 1.1E-56 T 30-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CL1_0090 31cb7e6cba4cc6028f5fa19651da0b18 570 PRINTS PR01043 Glycyl-tRNA synthetase signature 435 447 1.1E-56 T 30-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CL1_0090 31cb7e6cba4cc6028f5fa19651da0b18 570 PRINTS PR01043 Glycyl-tRNA synthetase signature 193 210 1.1E-56 T 30-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CL1_0090 31cb7e6cba4cc6028f5fa19651da0b18 570 PRINTS PR01043 Glycyl-tRNA synthetase signature 210 220 1.1E-56 T 30-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CL1_0090 31cb7e6cba4cc6028f5fa19651da0b18 570 PRINTS PR01043 Glycyl-tRNA synthetase signature 161 178 1.1E-56 T 30-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CL1_0090 31cb7e6cba4cc6028f5fa19651da0b18 570 PRINTS PR01043 Glycyl-tRNA synthetase signature 142 154 1.1E-56 T 30-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CL1_0090 31cb7e6cba4cc6028f5fa19651da0b18 570 PRINTS PR01043 Glycyl-tRNA synthetase signature 513 532 1.1E-56 T 30-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CL1_0090 31cb7e6cba4cc6028f5fa19651da0b18 570 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 158 342 1.1E-10 T 30-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CL1_0090 31cb7e6cba4cc6028f5fa19651da0b18 570 Gene3D G3DSA:1.10.30.30 363 426 1.1E-141 T 30-10-2018 CL1_0090 31cb7e6cba4cc6028f5fa19651da0b18 570 TIGRFAM TIGR00389 glyS_dimeric: glycine--tRNA ligase 7 565 1.2E-217 T 30-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CL1_0090 31cb7e6cba4cc6028f5fa19651da0b18 570 Hamap MF_00253_A Glycine--tRNA ligase [glyQS]. 6 568 46.811 T 30-10-2018 IPR022960 Glycine-tRNA ligase, archaeal GO:0004820 KEGG: 00970+6.1.1.14 CL1_0090 31cb7e6cba4cc6028f5fa19651da0b18 570 Gene3D G3DSA:3.40.50.800 473 570 7.4E-32 T 30-10-2018 IPR036621 Anticodon-binding domain superfamily CL1_0090 31cb7e6cba4cc6028f5fa19651da0b18 570 Gene3D G3DSA:1.20.1430.20 84 147 1.1E-141 T 30-10-2018 CL1_0477 f18e3e6d1923fceb3a759a568124a596 123 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 14 103 7.0E-21 T 30-10-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis CL1_0477 f18e3e6d1923fceb3a759a568124a596 123 SUPERFAMILY SSF53146 1 108 3.79E-31 T 30-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily CL1_0477 f18e3e6d1923fceb3a759a568124a596 123 Gene3D G3DSA:3.30.420.130 1 104 1.2E-31 T 30-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily CL1_0012 8e435806edc7b4638b478287b6c864af 396 SUPERFAMILY SSF52922 285 393 1.13E-23 T 30-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 CL1_0012 8e435806edc7b4638b478287b6c864af 396 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 34 270 1.2E-75 T 30-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 CL1_0012 8e435806edc7b4638b478287b6c864af 396 SUPERFAMILY SSF52518 23 278 3.44E-67 T 30-10-2018 IPR029061 Thiamin diphosphate-binding fold CL1_0012 8e435806edc7b4638b478287b6c864af 396 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 294 388 1.1E-18 T 30-10-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II CL1_0012 8e435806edc7b4638b478287b6c864af 396 Gene3D G3DSA:3.40.50.920 283 395 9.4E-24 T 30-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 CL1_0012 8e435806edc7b4638b478287b6c864af 396 Gene3D G3DSA:3.40.50.970 10 211 1.0E-76 T 30-10-2018 CL1_0142 5c4ada285c8b868b088e0ed644dd4581 294 Gene3D G3DSA:2.10.240.10 250 287 9.5E-8 T 30-10-2018 IPR037117 Dihydroorotate dehydrogenase, electron transfer subunit, Fe-S binding domain superfamily CL1_0142 5c4ada285c8b868b088e0ed644dd4581 294 SUPERFAMILY SSF63380 15 118 6.99E-24 T 30-10-2018 IPR017938 Riboflavin synthase-like beta-barrel CL1_0142 5c4ada285c8b868b088e0ed644dd4581 294 SUPERFAMILY SSF52343 110 285 1.7E-31 T 30-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain CL1_0142 5c4ada285c8b868b088e0ed644dd4581 294 PRINTS PR00410 Phenol hydroxylase reductase family signature 218 226 1.4E-7 T 30-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CL1_0142 5c4ada285c8b868b088e0ed644dd4581 294 PRINTS PR00410 Phenol hydroxylase reductase family signature 52 64 1.4E-7 T 30-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CL1_0142 5c4ada285c8b868b088e0ed644dd4581 294 PRINTS PR00410 Phenol hydroxylase reductase family signature 126 145 1.4E-7 T 30-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CL1_0142 5c4ada285c8b868b088e0ed644dd4581 294 Gene3D G3DSA:2.40.30.10 16 114 1.3E-19 T 30-10-2018 CL1_0142 5c4ada285c8b868b088e0ed644dd4581 294 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 250 286 9.1E-13 T 30-10-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain CL1_0142 5c4ada285c8b868b088e0ed644dd4581 294 Pfam PF00175 Oxidoreductase NAD-binding domain 127 231 3.7E-13 T 30-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 CL1_0142 5c4ada285c8b868b088e0ed644dd4581 294 PIRSF PIRSF006816 16 293 2.2E-83 T 30-10-2018 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 CL1_0142 5c4ada285c8b868b088e0ed644dd4581 294 Pfam PF00970 Oxidoreductase FAD-binding domain 35 113 7.5E-8 T 30-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 CL1_0142 5c4ada285c8b868b088e0ed644dd4581 294 Gene3D G3DSA:3.40.50.80 117 248 3.3E-22 T 30-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain CL1_0358 8194acdf9319dfe51069b6702657be47 438 TIGRFAM TIGR00458 aspS_nondisc: aspartate--tRNA(Asn) ligase 5 438 3.1E-185 T 30-10-2018 IPR004523 Aspartate-tRNA synthetase, type 2 GO:0000166|GO:0004815|GO:0005524|GO:0005737|GO:0006422 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CL1_0358 8194acdf9319dfe51069b6702657be47 438 Pfam PF01336 OB-fold nucleic acid binding domain 19 98 3.9E-12 T 30-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 CL1_0358 8194acdf9319dfe51069b6702657be47 438 Gene3D G3DSA:3.30.930.10 107 438 1.7E-123 T 30-10-2018 CL1_0358 8194acdf9319dfe51069b6702657be47 438 Pfam PF00152 tRNA synthetases class II (D, K and N) 118 432 1.1E-97 T 30-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CL1_0358 8194acdf9319dfe51069b6702657be47 438 PRINTS PR01042 Aspartyl-tRNA synthetase signature 393 407 2.7E-23 T 30-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CL1_0358 8194acdf9319dfe51069b6702657be47 438 PRINTS PR01042 Aspartyl-tRNA synthetase signature 204 217 2.7E-23 T 30-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CL1_0358 8194acdf9319dfe51069b6702657be47 438 PRINTS PR01042 Aspartyl-tRNA synthetase signature 353 369 2.7E-23 T 30-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CL1_0358 8194acdf9319dfe51069b6702657be47 438 PRINTS PR01042 Aspartyl-tRNA synthetase signature 187 199 2.7E-23 T 30-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CL1_0358 8194acdf9319dfe51069b6702657be47 438 Gene3D G3DSA:2.40.50.140 1 105 4.5E-28 T 30-10-2018 CL1_0358 8194acdf9319dfe51069b6702657be47 438 Hamap MF_02075 Aspartate--tRNA(Asp) ligase [aspS]. 2 438 43.981 T 30-10-2018 IPR004523 Aspartate-tRNA synthetase, type 2 GO:0000166|GO:0004815|GO:0005524|GO:0005737|GO:0006422 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CL1_0358 8194acdf9319dfe51069b6702657be47 438 SUPERFAMILY SSF50249 1 102 3.62E-27 T 30-10-2018 IPR012340 Nucleic acid-binding, OB-fold CL1_0358 8194acdf9319dfe51069b6702657be47 438 SUPERFAMILY SSF55681 96 437 1.14E-100 T 30-10-2018 CL1_0128 a0be40859fb193e43372ec6ae2b485fb 189 Gene3D G3DSA:3.30.2170.10 3 142 5.3E-35 T 30-10-2018 CL1_0128 a0be40859fb193e43372ec6ae2b485fb 189 Gene3D G3DSA:3.30.2170.10 143 189 1.1E-6 T 30-10-2018 CL1_0128 a0be40859fb193e43372ec6ae2b485fb 189 Pfam PF04493 Endonuclease V 16 141 2.5E-31 T 30-10-2018 IPR007581 Endonuclease V GO:0004519|GO:0006281 CL1_0128 a0be40859fb193e43372ec6ae2b485fb 189 Pfam PF04493 Endonuclease V 143 182 4.0E-5 T 30-10-2018 IPR007581 Endonuclease V GO:0004519|GO:0006281 CL1_1917 5db0a2ddaf71cc9f3319bf8698dcdfff 386 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 147 162 1.4E-28 T 30-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 CL1_1917 5db0a2ddaf71cc9f3319bf8698dcdfff 386 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 129 146 1.4E-28 T 30-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 CL1_1917 5db0a2ddaf71cc9f3319bf8698dcdfff 386 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 226 247 1.4E-28 T 30-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 CL1_1917 5db0a2ddaf71cc9f3319bf8698dcdfff 386 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 107 118 1.4E-28 T 30-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 CL1_1917 5db0a2ddaf71cc9f3319bf8698dcdfff 386 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 202 219 1.4E-28 T 30-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 CL1_1917 5db0a2ddaf71cc9f3319bf8698dcdfff 386 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 258 274 1.4E-28 T 30-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 CL1_1917 5db0a2ddaf71cc9f3319bf8698dcdfff 386 SUPERFAMILY SSF56726 81 383 2.09E-78 T 30-10-2018 IPR036078 Spo11/DNA topoisomerase VI subunit A superfamily GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 CL1_1917 5db0a2ddaf71cc9f3319bf8698dcdfff 386 Hamap MF_00132 Type 2 DNA topoisomerase 6 subunit A [top6A]. 17 385 40.349 T 30-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 CL1_1917 5db0a2ddaf71cc9f3319bf8698dcdfff 386 Pfam PF04406 Type IIB DNA topoisomerase 83 151 5.1E-19 T 30-10-2018 IPR013049 Spo11/DNA topoisomerase VI, subunit A, N-terminal GO:0003677|GO:0003824|GO:0005524|GO:0005694|GO:0006259 Reactome: R-HSA-912446 CL1_1917 5db0a2ddaf71cc9f3319bf8698dcdfff 386 Gene3D G3DSA:3.40.1360.10 156 385 5.7E-65 T 30-10-2018 CL1_1917 5db0a2ddaf71cc9f3319bf8698dcdfff 386 Gene3D G3DSA:1.10.10.10 14 155 3.8E-51 T 30-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CL1_1917 5db0a2ddaf71cc9f3319bf8698dcdfff 386 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 49 69 1.4E-47 T 30-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 CL1_1917 5db0a2ddaf71cc9f3319bf8698dcdfff 386 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 232 252 1.4E-47 T 30-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 CL1_1917 5db0a2ddaf71cc9f3319bf8698dcdfff 386 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 123 140 1.4E-47 T 30-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 CL1_1917 5db0a2ddaf71cc9f3319bf8698dcdfff 386 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 356 379 1.4E-47 T 30-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 CL1_1917 5db0a2ddaf71cc9f3319bf8698dcdfff 386 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 176 194 1.4E-47 T 30-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 CL1_1683 3256d19341fac2cdc2fba6ba5d7240cb 669 SUPERFAMILY SSF56300 128 395 2.06E-30 T 30-10-2018 CL1_1683 3256d19341fac2cdc2fba6ba5d7240cb 669 Pfam PF00149 Calcineurin-like phosphoesterase 129 370 3.8E-9 T 30-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CL1_1683 3256d19341fac2cdc2fba6ba5d7240cb 669 TIGRFAM TIGR04288 CGP_CTERM: CGP-CTERM domain 649 668 1.3E-7 T 30-10-2018 IPR027552 CGP-CTERM domain CL1_1683 3256d19341fac2cdc2fba6ba5d7240cb 669 Gene3D G3DSA:3.60.21.10 172 431 3.6E-19 T 30-10-2018 IPR029052 Metallo-dependent phosphatase-like CL1_1556 491b71e5c0ccaaa232128d7b6b4083bf 192 Pfam PF00881 Nitroreductase family 13 170 2.0E-25 T 30-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 CL1_1556 491b71e5c0ccaaa232128d7b6b4083bf 192 SUPERFAMILY SSF55469 6 192 5.23E-45 T 30-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CL1_1556 491b71e5c0ccaaa232128d7b6b4083bf 192 Gene3D G3DSA:3.40.109.10 4 189 2.4E-47 T 30-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CL1_0642 49f29cfe7f1006b26fe4670522c43a1f 288 Gene3D G3DSA:2.10.240.10 246 280 3.7E-8 T 30-10-2018 IPR037117 Dihydroorotate dehydrogenase, electron transfer subunit, Fe-S binding domain superfamily CL1_0642 49f29cfe7f1006b26fe4670522c43a1f 288 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 245 279 4.7E-13 T 30-10-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain CL1_0642 49f29cfe7f1006b26fe4670522c43a1f 288 Pfam PF00970 Oxidoreductase FAD-binding domain 16 99 5.3E-5 T 30-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 CL1_0642 49f29cfe7f1006b26fe4670522c43a1f 288 SUPERFAMILY SSF52343 96 279 2.49E-30 T 30-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain CL1_0642 49f29cfe7f1006b26fe4670522c43a1f 288 SUPERFAMILY SSF63380 2 104 7.53E-22 T 30-10-2018 IPR017938 Riboflavin synthase-like beta-barrel CL1_0642 49f29cfe7f1006b26fe4670522c43a1f 288 Pfam PF00175 Oxidoreductase NAD-binding domain 113 226 3.6E-11 T 30-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 CL1_0642 49f29cfe7f1006b26fe4670522c43a1f 288 PRINTS PR00410 Phenol hydroxylase reductase family signature 213 221 5.5E-12 T 30-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CL1_0642 49f29cfe7f1006b26fe4670522c43a1f 288 PRINTS PR00410 Phenol hydroxylase reductase family signature 39 51 5.5E-12 T 30-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CL1_0642 49f29cfe7f1006b26fe4670522c43a1f 288 PRINTS PR00410 Phenol hydroxylase reductase family signature 137 146 5.5E-12 T 30-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CL1_0642 49f29cfe7f1006b26fe4670522c43a1f 288 PRINTS PR00410 Phenol hydroxylase reductase family signature 112 131 5.5E-12 T 30-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CL1_0642 49f29cfe7f1006b26fe4670522c43a1f 288 Gene3D G3DSA:2.40.30.10 2 100 1.7E-19 T 30-10-2018 CL1_0642 49f29cfe7f1006b26fe4670522c43a1f 288 PIRSF PIRSF006816 3 288 4.2E-81 T 30-10-2018 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 CL1_0642 49f29cfe7f1006b26fe4670522c43a1f 288 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 112 131 1.2E-7 T 30-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CL1_0642 49f29cfe7f1006b26fe4670522c43a1f 288 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 149 160 1.2E-7 T 30-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CL1_0642 49f29cfe7f1006b26fe4670522c43a1f 288 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 137 146 1.2E-7 T 30-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CL1_0642 49f29cfe7f1006b26fe4670522c43a1f 288 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 213 221 1.2E-7 T 30-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CL1_0642 49f29cfe7f1006b26fe4670522c43a1f 288 Gene3D G3DSA:3.40.50.80 102 245 3.9E-22 T 30-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain CL1_1885 463f5fa5054e1527a38804ac74cefa9f 405 Gene3D G3DSA:3.40.50.1950 15 186 2.2E-47 T 30-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 CL1_1885 463f5fa5054e1527a38804ac74cefa9f 405 Gene3D G3DSA:3.40.50.10300 187 405 1.9E-72 T 30-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 CL1_1885 463f5fa5054e1527a38804ac74cefa9f 405 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 18 399 1.3E-129 T 30-10-2018 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5|MetaCyc: PWY-7851 CL1_1885 463f5fa5054e1527a38804ac74cefa9f 405 Pfam PF02441 Flavoprotein 19 188 1.5E-41 T 30-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CL1_1885 463f5fa5054e1527a38804ac74cefa9f 405 SUPERFAMILY SSF102645 180 404 1.23E-67 T 30-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 CL1_1885 463f5fa5054e1527a38804ac74cefa9f 405 SUPERFAMILY SSF52507 18 217 9.03E-48 T 30-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 CL1_1885 463f5fa5054e1527a38804ac74cefa9f 405 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 193 374 3.3E-58 T 30-10-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 CL1_1393 5dafae313574e35b1edef6e231de7138 213 Pfam PF01914 MarC family integral membrane protein 6 211 1.8E-61 T 30-10-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 CL1_1393 5dafae313574e35b1edef6e231de7138 213 TIGRFAM TIGR00427 TIGR00427: membrane protein, MarC family 4 207 4.8E-65 T 30-10-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 CL1_0201 cad7f538ea8fe071693f45a3d59aedc6 394 ProSitePatterns PS00535 Respiratory chain NADH dehydrogenase 49 Kd subunit signature. 64 75 - T 30-10-2018 IPR014029 NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CL1_0201 cad7f538ea8fe071693f45a3d59aedc6 394 SUPERFAMILY SSF56762 41 394 1.44E-93 T 30-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CL1_0201 cad7f538ea8fe071693f45a3d59aedc6 394 Gene3D G3DSA:1.10.645.20 30 394 1.1E-113 T 30-10-2018 IPR038290 NADH-quinone oxidoreductase, subunit D superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CL1_0201 cad7f538ea8fe071693f45a3d59aedc6 394 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 142 394 4.5E-72 T 30-10-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CL1_1766 89e22618705e6f4fcfe0b4883d2e3918 925 Gene3D G3DSA:3.40.50.300 4 202 8.6E-46 T 30-10-2018 CL1_1766 89e22618705e6f4fcfe0b4883d2e3918 925 SMART SM00490 259 341 2.2E-24 T 30-10-2018 IPR001650 Helicase, C-terminal CL1_1766 89e22618705e6f4fcfe0b4883d2e3918 925 SMART SM00487 12 210 2.4E-35 T 30-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CL1_1766 89e22618705e6f4fcfe0b4883d2e3918 925 Pfam PF00271 Helicase conserved C-terminal domain 242 336 9.5E-19 T 30-10-2018 IPR001650 Helicase, C-terminal CL1_1766 89e22618705e6f4fcfe0b4883d2e3918 925 Gene3D G3DSA:3.40.50.300 222 372 9.5E-30 T 30-10-2018 CL1_1766 89e22618705e6f4fcfe0b4883d2e3918 925 SUPERFAMILY SSF52540 27 350 1.11E-51 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_1766 89e22618705e6f4fcfe0b4883d2e3918 925 Pfam PF08494 DEAD/H associated 583 750 1.0E-16 T 30-10-2018 IPR013701 DEAD/H associated GO:0005524|GO:0016818 CL1_1766 89e22618705e6f4fcfe0b4883d2e3918 925 Pfam PF00270 DEAD/DEAH box helicase 18 182 3.3E-26 T 30-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CL1_1766 89e22618705e6f4fcfe0b4883d2e3918 925 PIRSF PIRSF037307 1 912 0.0 T 30-10-2018 IPR017170 Lhr-like ATP-dependent RNA helicase, predicted GO:0005524|GO:0016818 CL1_1011 156010c8c57bcd6cae478f5eec5b0bad 93 ProDom PD188822 UPF0330 AF1997 ST1125.1 AF1689 AF1478 C1_0043 PYRAB04040 PF1222 MM2475 MA1514 17 75 5.0E-21 T 30-10-2018 IPR003847 Putative antitoxin CL1_1011 156010c8c57bcd6cae478f5eec5b0bad 93 Hamap MF_00794 Putative antitoxin . 16 89 17.114 T 30-10-2018 IPR003847 Putative antitoxin CL1_1011 156010c8c57bcd6cae478f5eec5b0bad 93 Pfam PF02697 Putative antitoxin 17 82 5.4E-20 T 30-10-2018 IPR003847 Putative antitoxin CL1_1490 83bd92fb3fa56ebaadaa07641899a64b 67 SUPERFAMILY SSF116820 1 60 1.57E-23 T 30-10-2018 IPR036401 Ribosomal protein S17e-like superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_1490 83bd92fb3fa56ebaadaa07641899a64b 67 Hamap MF_00511 30S ribosomal protein S17e [rps17e]. 1 63 22.141 T 30-10-2018 IPR001210 Ribosomal protein S17e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_1490 83bd92fb3fa56ebaadaa07641899a64b 67 ProSitePatterns PS00712 Ribosomal protein S17e signature. 41 56 - T 30-10-2018 IPR018273 Ribosomal protein S17e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_1490 83bd92fb3fa56ebaadaa07641899a64b 67 Pfam PF00833 Ribosomal S17 1 64 6.8E-15 T 30-10-2018 IPR001210 Ribosomal protein S17e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_1490 83bd92fb3fa56ebaadaa07641899a64b 67 Gene3D G3DSA:1.10.60.20 1 62 3.2E-29 T 30-10-2018 IPR036401 Ribosomal protein S17e-like superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_1721 df221e1fe1981899ced9baf1e7050662 655 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 418 430 - T 30-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 CL1_1721 df221e1fe1981899ced9baf1e7050662 655 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 315 337 - T 30-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 CL1_1721 df221e1fe1981899ced9baf1e7050662 655 Pfam PF00069 Protein kinase domain 309 548 1.3E-43 T 30-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CL1_1721 df221e1fe1981899ced9baf1e7050662 655 SUPERFAMILY SSF56112 297 554 2.05E-60 T 30-10-2018 IPR011009 Protein kinase-like domain superfamily CL1_1721 df221e1fe1981899ced9baf1e7050662 655 Gene3D G3DSA:1.10.510.10 282 573 9.4E-61 T 30-10-2018 CL1_1721 df221e1fe1981899ced9baf1e7050662 655 SMART SM00220 309 560 1.7E-48 T 30-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CL1_1779 0ffca38eac0b99527cfb5227a9c74c43 118 Pfam PF02001 Protein of unknown function DUF134 13 103 1.8E-26 T 30-10-2018 IPR002852 Uncharacterised protein family UPF0251 CL1_1779 0ffca38eac0b99527cfb5227a9c74c43 118 Hamap MF_00674 UPF0251 protein . 14 111 23.724 T 30-10-2018 IPR002852 Uncharacterised protein family UPF0251 CL1_1779 0ffca38eac0b99527cfb5227a9c74c43 118 SUPERFAMILY SSF88659 49 95 6.92E-9 T 30-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like CL1_1779 0ffca38eac0b99527cfb5227a9c74c43 118 Gene3D G3DSA:1.10.10.10 47 96 2.5E-10 T 30-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CL1_1476 5a49af73f12e5535ae6a4cecc82eb170 225 TIGRFAM TIGR00290 MJ0570_dom: MJ0570-related uncharacterized domain 1 220 9.7E-83 T 30-10-2018 IPR002761 Diphthamide synthase domain MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 CL1_1476 5a49af73f12e5535ae6a4cecc82eb170 225 Gene3D G3DSA:3.40.50.620 1 134 1.8E-46 T 30-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CL1_1476 5a49af73f12e5535ae6a4cecc82eb170 225 Gene3D G3DSA:3.90.1490.10 137 225 6.3E-32 T 30-10-2018 CL1_1476 5a49af73f12e5535ae6a4cecc82eb170 225 Pfam PF01902 Diphthamide synthase 1 220 2.1E-85 T 30-10-2018 IPR002761 Diphthamide synthase domain MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 CL1_1476 5a49af73f12e5535ae6a4cecc82eb170 225 SUPERFAMILY SSF52402 1 220 7.22E-74 T 30-10-2018 CL1_1476 5a49af73f12e5535ae6a4cecc82eb170 225 PIRSF PIRSF039123 1 225 4.9E-80 T 30-10-2018 IPR030662 Diphthine--ammonia ligase/Uncharacterised protein MJ0570 MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 CL1_1476 5a49af73f12e5535ae6a4cecc82eb170 225 TIGRFAM TIGR00289 TIGR00289: TIGR00289 family protein 1 221 4.4E-92 T 30-10-2018 IPR005237 Uncharacterised protein MJ0570 CL1_1476 5a49af73f12e5535ae6a4cecc82eb170 225 TIGRFAM TIGR03679 arCOG00187: arCOG00187 universal archaeal metal-binding-domain/4Fe-4S-binding-domain containing ABC transporter, ATP-binding protein 4 217 3.8E-88 T 30-10-2018 IPR022427 Uncharacterised protein MJ0570, ATP-binding CL1_0688 726f23a934a3ef3eeba81f9ef6b7ea01 392 Gene3D G3DSA:1.20.1250.20 12 203 5.2E-26 T 30-10-2018 CL1_0688 726f23a934a3ef3eeba81f9ef6b7ea01 392 SUPERFAMILY SSF103473 12 390 3.27E-59 T 30-10-2018 IPR036259 MFS transporter superfamily CL1_0688 726f23a934a3ef3eeba81f9ef6b7ea01 392 Gene3D G3DSA:1.20.1250.20 209 392 1.1E-20 T 30-10-2018 CL1_0688 726f23a934a3ef3eeba81f9ef6b7ea01 392 Pfam PF07690 Major Facilitator Superfamily 19 257 1.4E-24 T 30-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CL1_1761 88d4ace87d61a365cc743e9d84f018a6 239 SMART SM00849 31 221 1.0E-38 T 30-10-2018 IPR001279 Metallo-beta-lactamase CL1_1761 88d4ace87d61a365cc743e9d84f018a6 239 Pfam PF00753 Metallo-beta-lactamase superfamily 31 221 2.1E-24 T 30-10-2018 IPR001279 Metallo-beta-lactamase CL1_1761 88d4ace87d61a365cc743e9d84f018a6 239 Gene3D G3DSA:3.60.15.10 6 235 1.3E-45 T 30-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like CL1_1761 88d4ace87d61a365cc743e9d84f018a6 239 SUPERFAMILY SSF56281 12 238 1.76E-45 T 30-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like CL1_1955 5bde1b25368571cd3dcc20a6d4ad378f 293 Pfam PF03787 RAMP superfamily 18 242 2.5E-20 T 30-10-2018 IPR005537 CRISPR type III-associated RAMP protein CL1_1955 5bde1b25368571cd3dcc20a6d4ad378f 293 TIGRFAM TIGR02582 cas7_TM1809: CRISPR type III-A/MTUBE-associated RAMP protein Csm3 10 243 1.7E-60 T 30-10-2018 IPR013412 CRISPR-associated RAMP Csm3 CL1_0656 af5dfa0f83ee4832147f20c38d3c6ea3 155 Pfam PF00364 Biotin-requiring enzyme 89 154 8.4E-25 T 30-10-2018 IPR000089 Biotin/lipoyl attachment CL1_0656 af5dfa0f83ee4832147f20c38d3c6ea3 155 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 111 128 - T 30-10-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CL1_0656 af5dfa0f83ee4832147f20c38d3c6ea3 155 Gene3D G3DSA:2.40.50.100 82 155 8.1E-29 T 30-10-2018 CL1_0656 af5dfa0f83ee4832147f20c38d3c6ea3 155 SUPERFAMILY SSF51230 79 154 1.31E-26 T 30-10-2018 IPR011053 Single hybrid motif CL1_1045 21116d72586b29feb72be80c80187685 424 SUPERFAMILY SSF51338 1 423 1.35E-38 T 30-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 CL1_1045 21116d72586b29feb72be80c80187685 424 Gene3D G3DSA:3.20.20.140 55 344 1.1E-159 T 30-10-2018 CL1_1045 21116d72586b29feb72be80c80187685 424 Pfam PF01979 Amidohydrolase family 51 397 1.2E-79 T 30-10-2018 IPR006680 Amidohydrolase-related GO:0016787 CL1_1045 21116d72586b29feb72be80c80187685 424 SUPERFAMILY SSF51556 54 347 4.33E-106 T 30-10-2018 IPR032466 Metal-dependent hydrolase CL1_1045 21116d72586b29feb72be80c80187685 424 Gene3D G3DSA:2.30.40.10 4 416 1.1E-159 T 30-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 CL1_1045 21116d72586b29feb72be80c80187685 424 Hamap MF_01281 5'-deoxyadenosine deaminase [dadD]. 2 424 48.641 T 30-10-2018 IPR023512 Deaminase MtaD/DadD GO:0019239 CL1_1255 2de733c00bb1ab52dcb61cf83d56b72d 124 Pfam PF01850 PIN domain 3 118 6.6E-19 T 30-10-2018 IPR002716 PIN domain CL1_1255 2de733c00bb1ab52dcb61cf83d56b72d 124 Gene3D G3DSA:3.40.50.1010 2 123 1.8E-15 T 30-10-2018 CL1_1255 2de733c00bb1ab52dcb61cf83d56b72d 124 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 3 124 10.328 T 30-10-2018 IPR022907 VapC family GO:0004540 CL1_1255 2de733c00bb1ab52dcb61cf83d56b72d 124 SUPERFAMILY SSF88723 2 122 1.15E-22 T 30-10-2018 IPR029060 PIN-like domain superfamily CL1_1922 0cac1a13ecfc4da66c1f202b4bc768b8 267 Hamap MF_01527_A GTP cyclohydrolase FolE2 [folE2]. 1 267 26.755 T 30-10-2018 IPR022840 GTP cyclohydrolase MptA GO:0003933 KEGG: 00790+3.5.4.39|MetaCyc: PWY-6797|MetaCyc: PWY-7853 CL1_1922 0cac1a13ecfc4da66c1f202b4bc768b8 267 Pfam PF02649 Type I GTP cyclohydrolase folE2 4 263 2.1E-65 T 30-10-2018 IPR003801 GTP cyclohydrolase FolE2/MptA GO:0003933 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852 CL1_1922 0cac1a13ecfc4da66c1f202b4bc768b8 267 Gene3D G3DSA:3.10.270.10 1 266 2.5E-67 T 30-10-2018 CL1_1708 d5e4442707108d248d9d1af54b2b042b 170 TIGRFAM TIGR00288 TIGR00288: TIGR00288 family protein 22 165 3.9E-61 T 30-10-2018 IPR002790 Conserved hypothetical protein CHP00288 CL1_1708 d5e4442707108d248d9d1af54b2b042b 170 ProDom PD010896 FAMILY DUF88 ARCHAEBACTERIAL PROTEIN MJ0482 PH0073 PF2040 VNG1608C MA3857 PF2039 33 105 9.0E-29 T 30-10-2018 CL1_1708 d5e4442707108d248d9d1af54b2b042b 170 Gene3D G3DSA:3.40.50.1010 24 165 2.5E-8 T 30-10-2018 CL1_1708 d5e4442707108d248d9d1af54b2b042b 170 Pfam PF01936 NYN domain 32 162 1.1E-18 T 30-10-2018 IPR021139 NYN domain, limkain-b1-type CL1_1401 d1b90360fee66d36d298a833ed87decd 424 Gene3D G3DSA:3.30.420.220 1 125 2.1E-47 T 30-10-2018 CL1_1401 d1b90360fee66d36d298a833ed87decd 424 Gene3D G3DSA:1.10.287.660 131 243 1.1E-37 T 30-10-2018 IPR029012 Helix hairpin bin domain superfamily CL1_1401 d1b90360fee66d36d298a833ed87decd 424 Gene3D G3DSA:1.10.246.90 244 368 1.9E-51 T 30-10-2018 CL1_1401 d1b90360fee66d36d298a833ed87decd 424 Pfam PF01798 snoRNA binding domain, fibrillarin 138 363 1.2E-70 T 30-10-2018 IPR002687 Nop domain CL1_1401 d1b90360fee66d36d298a833ed87decd 424 Gene3D G3DSA:1.10.150.460 161 212 1.1E-37 T 30-10-2018 CL1_1401 d1b90360fee66d36d298a833ed87decd 424 SMART SM00931 130 182 7.1E-28 T 30-10-2018 IPR012976 NOSIC CL1_1401 d1b90360fee66d36d298a833ed87decd 424 SUPERFAMILY SSF89124 126 365 1.14E-79 T 30-10-2018 IPR036070 Nop domain superfamily CL1_0268 b40d3517d8b5fb5d1c6f45292cbfa7e2 573 Gene3D G3DSA:3.10.580.10 438 565 1.1E-25 T 30-10-2018 CL1_0268 b40d3517d8b5fb5d1c6f45292cbfa7e2 573 SMART SM00116 452 500 1.1E-10 T 30-10-2018 IPR000644 CBS domain CL1_0268 b40d3517d8b5fb5d1c6f45292cbfa7e2 573 SMART SM00116 513 564 0.043 T 30-10-2018 IPR000644 CBS domain CL1_0268 b40d3517d8b5fb5d1c6f45292cbfa7e2 573 PRINTS PR00762 Chloride channel signature 162 181 3.9E-17 T 30-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CL1_0268 b40d3517d8b5fb5d1c6f45292cbfa7e2 573 PRINTS PR00762 Chloride channel signature 362 378 3.9E-17 T 30-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CL1_0268 b40d3517d8b5fb5d1c6f45292cbfa7e2 573 PRINTS PR00762 Chloride channel signature 82 99 3.9E-17 T 30-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CL1_0268 b40d3517d8b5fb5d1c6f45292cbfa7e2 573 PRINTS PR00762 Chloride channel signature 327 347 3.9E-17 T 30-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CL1_0268 b40d3517d8b5fb5d1c6f45292cbfa7e2 573 SUPERFAMILY SSF81340 9 432 1.57E-97 T 30-10-2018 IPR014743 Chloride channel, core Reactome: R-HSA-2672351 CL1_0268 b40d3517d8b5fb5d1c6f45292cbfa7e2 573 Pfam PF00654 Voltage gated chloride channel 70 412 1.9E-83 T 30-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 CL1_0268 b40d3517d8b5fb5d1c6f45292cbfa7e2 573 SUPERFAMILY SSF54631 438 564 5.81E-28 T 30-10-2018 CL1_0268 b40d3517d8b5fb5d1c6f45292cbfa7e2 573 Pfam PF00571 CBS domain 445 498 4.0E-14 T 30-10-2018 IPR000644 CBS domain CL1_0268 b40d3517d8b5fb5d1c6f45292cbfa7e2 573 Pfam PF00571 CBS domain 518 562 1.9E-7 T 30-10-2018 IPR000644 CBS domain CL1_0268 b40d3517d8b5fb5d1c6f45292cbfa7e2 573 Gene3D G3DSA:1.10.3080.10 13 437 2.8E-92 T 30-10-2018 IPR014743 Chloride channel, core Reactome: R-HSA-2672351 CL1_1883 64def64482fd08065fd945a2870bf30f 226 SUPERFAMILY SSF53681 116 224 3.05E-24 T 30-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CL1_1883 64def64482fd08065fd945a2870bf30f 226 Pfam PF01177 Asp/Glu/Hydantoin racemase 7 220 1.8E-51 T 30-10-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CL1_1883 64def64482fd08065fd945a2870bf30f 226 TIGRFAM TIGR00035 asp_race: aspartate racemase 1 224 1.6E-49 T 30-10-2018 IPR004380 Aspartate racemase GO:0006520|GO:0016855 CL1_1883 64def64482fd08065fd945a2870bf30f 226 ProSitePatterns PS00924 Aspartate and glutamate racemases signature 2. 189 199 - T 30-10-2018 IPR033134 Asp/Glu racemase, active site 2 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CL1_1883 64def64482fd08065fd945a2870bf30f 226 Gene3D G3DSA:3.40.50.1860 3 215 1.5E-73 T 30-10-2018 CL1_1883 64def64482fd08065fd945a2870bf30f 226 Gene3D G3DSA:3.40.50.1860 102 211 1.5E-73 T 30-10-2018 CL1_1883 64def64482fd08065fd945a2870bf30f 226 SUPERFAMILY SSF53681 1 114 4.36E-28 T 30-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CL1_1691 2ba6b21074dbeba23d0b8f0644d8532f 866 SUPERFAMILY SSF52540 227 552 2.31E-50 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_1691 2ba6b21074dbeba23d0b8f0644d8532f 866 SMART SM00487 213 410 1.0E-30 T 30-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CL1_1691 2ba6b21074dbeba23d0b8f0644d8532f 866 Gene3D G3DSA:3.40.50.300 200 402 3.8E-51 T 30-10-2018 CL1_1691 2ba6b21074dbeba23d0b8f0644d8532f 866 Pfam PF00270 DEAD/DEAH box helicase 219 382 5.8E-25 T 30-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CL1_1691 2ba6b21074dbeba23d0b8f0644d8532f 866 SMART SM00490 453 538 3.1E-20 T 30-10-2018 IPR001650 Helicase, C-terminal CL1_1691 2ba6b21074dbeba23d0b8f0644d8532f 866 Gene3D G3DSA:3.40.50.300 404 585 3.4E-29 T 30-10-2018 CL1_1691 2ba6b21074dbeba23d0b8f0644d8532f 866 Pfam PF00271 Helicase conserved C-terminal domain 434 536 1.4E-13 T 30-10-2018 IPR001650 Helicase, C-terminal CL1_1497 87e6fc5ffb65df026a3450439bdf72b2 222 Hamap MF_00264 UPF0128 protein . 1 222 129.853 T 30-10-2018 IPR005266 Uncharacterised protein family UPF0128 CL1_1497 87e6fc5ffb65df026a3450439bdf72b2 222 TIGRFAM TIGR00703 TIGR00703: TIGR00703 family protein 1 222 7.4E-95 T 30-10-2018 IPR005266 Uncharacterised protein family UPF0128 CL1_1497 87e6fc5ffb65df026a3450439bdf72b2 222 Pfam PF03673 Uncharacterised protein family (UPF0128) 1 222 1.8E-102 T 30-10-2018 IPR005266 Uncharacterised protein family UPF0128 CL1_1497 87e6fc5ffb65df026a3450439bdf72b2 222 ProDom PD023377 UPF0128 PYRAB08320 PH1314 PF1488 MJ1463 AQ_756 1 222 5.0E-113 T 30-10-2018 IPR005266 Uncharacterised protein family UPF0128 CL1_1711 b73cc41d33c5553a02318e9e2d74bacb 377 TIGRFAM TIGR04288 CGP_CTERM: CGP-CTERM domain 358 377 2.2E-8 T 30-10-2018 IPR027552 CGP-CTERM domain CL1_1711 b73cc41d33c5553a02318e9e2d74bacb 377 SUPERFAMILY SSF53850 24 331 1.97E-79 T 30-10-2018 CL1_1711 b73cc41d33c5553a02318e9e2d74bacb 377 TIGRFAM TIGR01254 sfuA: ABC transporter periplasmic binding protein, thiB subfamily 25 330 1.5E-99 T 30-10-2018 IPR005948 Thiamine/thiamin pyrophosphate-binding periplasmic protein, ABC transporter GO:0015888|GO:0030975 CL1_1711 b73cc41d33c5553a02318e9e2d74bacb 377 Gene3D G3DSA:3.40.190.10 131 331 6.0E-119 T 30-10-2018 CL1_1711 b73cc41d33c5553a02318e9e2d74bacb 377 Pfam PF13343 Bacterial extracellular solute-binding protein 77 300 6.2E-32 T 30-10-2018 CL1_1711 b73cc41d33c5553a02318e9e2d74bacb 377 PIRSF PIRSF002825 1 335 2.4E-51 T 30-10-2018 IPR026045 Ferric binding protein CL1_1711 b73cc41d33c5553a02318e9e2d74bacb 377 Gene3D G3DSA:3.40.190.10 30 306 6.0E-119 T 30-10-2018 CL1_0888 d1059e791441af9c5cf64db19751ac25 1351 SUPERFAMILY SSF88713 32 576 1.61E-64 T 30-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CL1_0888 d1059e791441af9c5cf64db19751ac25 1351 Pfam PF03065 Glycosyl hydrolase family 57 36 537 1.4E-123 T 30-10-2018 IPR004300 Glycoside hydrolase family 57, N-terminal domain GO:0003824|GO:0005975 CL1_0888 d1059e791441af9c5cf64db19751ac25 1351 SUPERFAMILY SSF49344 1035 1268 3.92E-76 T 30-10-2018 CL1_0888 d1059e791441af9c5cf64db19751ac25 1351 TIGRFAM TIGR04288 CGP_CTERM: CGP-CTERM domain 1331 1350 1.8E-5 T 30-10-2018 IPR027552 CGP-CTERM domain CL1_0888 d1059e791441af9c5cf64db19751ac25 1351 Gene3D G3DSA:3.20.110.20 230 502 1.1E-22 T 30-10-2018 CL1_0888 d1059e791441af9c5cf64db19751ac25 1351 SUPERFAMILY SSF49344 791 1025 3.65E-79 T 30-10-2018 CL1_0888 d1059e791441af9c5cf64db19751ac25 1351 Gene3D G3DSA:2.60.40.1190 1034 1269 1.9E-61 T 30-10-2018 CL1_0888 d1059e791441af9c5cf64db19751ac25 1351 Gene3D G3DSA:2.60.40.1190 789 1028 2.9E-65 T 30-10-2018 CL1_0888 d1059e791441af9c5cf64db19751ac25 1351 Pfam PF09985 C-terminal binding-module, SLH-like, of glucodextranase 1036 1265 2.4E-74 T 30-10-2018 IPR019248 Glucodextranase-like, C-terminal CL1_0888 d1059e791441af9c5cf64db19751ac25 1351 Pfam PF09985 C-terminal binding-module, SLH-like, of glucodextranase 792 1024 8.4E-78 T 30-10-2018 IPR019248 Glucodextranase-like, C-terminal CL1_0431 45019de7cfeb75cc304ebf947f99d9b8 235 Pfam PF13367 Protease prsW family 31 203 9.3E-30 T 30-10-2018 IPR026898 Protease PrsW GO:0008233 CL1_0431 45019de7cfeb75cc304ebf947f99d9b8 235 PIRSF PIRSF016933 4 226 1.7E-32 T 30-10-2018 IPR023596 Peptidase PrsW, archaeal/bacterial GO:0008233 CL1_0829 0884922748e3a6768c1cdbf7b20a10d3 366 Pfam PF04007 Protein of unknown function (DUF354) 11 315 1.1E-10 T 30-10-2018 IPR007152 Protein of unknown function DUF354 CL1_0829 0884922748e3a6768c1cdbf7b20a10d3 366 SUPERFAMILY SSF53756 1 326 3.87E-14 T 30-10-2018 CL1_0829 0884922748e3a6768c1cdbf7b20a10d3 366 Gene3D G3DSA:3.40.50.2000 14 101 1.2E-6 T 30-10-2018 CL1_0829 0884922748e3a6768c1cdbf7b20a10d3 366 PIRSF PIRSF005357 1 351 3.9E-68 T 30-10-2018 IPR007152 Protein of unknown function DUF354 CL1_1028 550d8382efa6b5ea02520c76e9e722f3 416 Gene3D G3DSA:1.10.3720.10 203 414 1.1E-11 T 30-10-2018 IPR035906 MetI-like superfamily CL1_1028 550d8382efa6b5ea02520c76e9e722f3 416 SUPERFAMILY SSF161098 209 404 3.66E-14 T 30-10-2018 IPR035906 MetI-like superfamily CL1_1028 550d8382efa6b5ea02520c76e9e722f3 416 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 232 406 4.0E-10 T 30-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 CL1_0256 a6664d81a4a22fe4c52698835b0b1395 309 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 233 249 8.6E-30 T 30-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase CL1_0256 a6664d81a4a22fe4c52698835b0b1395 309 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 117 127 8.6E-30 T 30-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase CL1_0256 a6664d81a4a22fe4c52698835b0b1395 309 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 183 195 8.6E-30 T 30-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase CL1_0256 a6664d81a4a22fe4c52698835b0b1395 309 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 291 308 8.6E-30 T 30-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase CL1_0256 a6664d81a4a22fe4c52698835b0b1395 309 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 88 102 8.6E-30 T 30-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase CL1_0256 a6664d81a4a22fe4c52698835b0b1395 309 ProSitePatterns PS01153 NOL1/NOP2/sun family signature. 182 193 - T 30-10-2018 IPR018314 Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site GO:0003723|GO:0008168 CL1_0256 a6664d81a4a22fe4c52698835b0b1395 309 Pfam PF17125 N-terminal domain of 16S rRNA methyltransferase RsmF 12 102 5.6E-20 T 30-10-2018 IPR031341 Ribosomal RNA small subunit methyltransferase F, N-terminal Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 CL1_0256 a6664d81a4a22fe4c52698835b0b1395 309 Gene3D G3DSA:3.30.70.3130 1 101 2.7E-35 T 30-10-2018 CL1_0256 a6664d81a4a22fe4c52698835b0b1395 309 Gene3D G3DSA:3.40.50.150 103 309 1.3E-69 T 30-10-2018 CL1_0256 a6664d81a4a22fe4c52698835b0b1395 309 SUPERFAMILY SSF53335 7 308 8.05E-77 T 30-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CL1_0256 a6664d81a4a22fe4c52698835b0b1395 309 Pfam PF01189 16S rRNA methyltransferase RsmB/F 106 307 3.3E-58 T 30-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 CL1_0256 a6664d81a4a22fe4c52698835b0b1395 309 TIGRFAM TIGR00446 nop2p: NOL1/NOP2/sun family putative RNA methylase 42 308 1.8E-89 T 30-10-2018 IPR011023 Nop2p GO:0003723|GO:0006364|GO:0008757 Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 CL1_0408 2a918f62e39abb3e30c9598c928c6364 133 SUPERFAMILY SSF110455 19 96 9.81E-7 T 30-10-2018 CL1_0408 2a918f62e39abb3e30c9598c928c6364 133 Pfam PF01751 Toprim domain 51 86 4.4E-6 T 30-10-2018 IPR006171 TOPRIM domain CL1_0408 2a918f62e39abb3e30c9598c928c6364 133 Hamap MF_01095 UPF0292 protein . 3 123 33.651 T 30-10-2018 IPR022972 Uncharacterised protein family UPF0292 CL1_0408 2a918f62e39abb3e30c9598c928c6364 133 Gene3D G3DSA:3.40.1360.10 3 117 3.4E-23 T 30-10-2018 CL1_0408 2a918f62e39abb3e30c9598c928c6364 133 SMART SM00493 20 90 1.4E-6 T 30-10-2018 IPR006171 TOPRIM domain CL1_1776 d1e0549b4f496e88322458f620ad87b8 91 Gene3D G3DSA:3.30.110.20 2 90 2.4E-38 T 30-10-2018 IPR036882 Alba-like domain superfamily GO:0003676 CL1_1776 d1e0549b4f496e88322458f620ad87b8 91 ProDom PD010497 ALBA DNA-BINDING DNA/RNA-BINDING RNA-BINDING ACETYLATION 3D-STRUCTURE DNA CONDENSATION AF1 SSO10B 8 90 8.0E-40 T 30-10-2018 CL1_1776 d1e0549b4f496e88322458f620ad87b8 91 PIRSF PIRSF028732 1 91 4.4E-40 T 30-10-2018 IPR013795 DNA/RNA-binding protein Alba GO:0003677|GO:0003723|GO:0005737 CL1_1776 d1e0549b4f496e88322458f620ad87b8 91 TIGRFAM TIGR00285 TIGR00285: DNA-binding protein Alba 4 90 1.0E-45 T 30-10-2018 IPR013795 DNA/RNA-binding protein Alba GO:0003677|GO:0003723|GO:0005737 CL1_1776 d1e0549b4f496e88322458f620ad87b8 91 Hamap MF_01122 DNA/RNA-binding protein Alba [albA]. 1 90 28.019 T 30-10-2018 IPR013795 DNA/RNA-binding protein Alba GO:0003677|GO:0003723|GO:0005737 CL1_1776 d1e0549b4f496e88322458f620ad87b8 91 SUPERFAMILY SSF82704 5 90 6.93E-27 T 30-10-2018 IPR036882 Alba-like domain superfamily GO:0003676 CL1_1776 d1e0549b4f496e88322458f620ad87b8 91 Pfam PF01918 Alba 6 66 8.3E-22 T 30-10-2018 IPR002775 DNA/RNA-binding protein Alba-like GO:0003676 CL1_0599 324d021ad0ed0fbe8f7b2922027369be 83 SUPERFAMILY SSF50104 2 80 2.41E-20 T 30-10-2018 IPR008991 Translation protein SH3-like domain superfamily CL1_0599 324d021ad0ed0fbe8f7b2922027369be 83 Hamap MF_00721 50S ribosomal protein L14e [rpl14e]. 1 79 26.937 T 30-10-2018 IPR023651 Ribosomal protein L14e GO:0003735|GO:0005840|GO:0006412 CL1_0599 324d021ad0ed0fbe8f7b2922027369be 83 Pfam PF01929 Ribosomal protein L14 44 81 1.9E-4 T 30-10-2018 IPR002784 Ribosomal protein L14e domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0599 324d021ad0ed0fbe8f7b2922027369be 83 Gene3D G3DSA:2.30.30.30 2 83 4.5E-30 T 30-10-2018 IPR014722 Ribosomal protein L2, domain 2 CL1_0889 b332e8ee308e5961128c8d3ccb728595 372 SUPERFAMILY SSF50331 242 370 7.78E-24 T 30-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal CL1_0889 b332e8ee308e5961128c8d3ccb728595 372 Gene3D G3DSA:2.40.50.140 310 354 2.3E-24 T 30-10-2018 CL1_0889 b332e8ee308e5961128c8d3ccb728595 372 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 30-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CL1_0889 b332e8ee308e5961128c8d3ccb728595 372 SMART SM00382 28 217 6.6E-14 T 30-10-2018 IPR003593 AAA+ ATPase domain CL1_0889 b332e8ee308e5961128c8d3ccb728595 372 Pfam PF08402 TOBE domain 288 363 4.5E-5 T 30-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 CL1_0889 b332e8ee308e5961128c8d3ccb728595 372 Pfam PF00005 ABC transporter 20 167 3.6E-31 T 30-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CL1_0889 b332e8ee308e5961128c8d3ccb728595 372 Gene3D G3DSA:3.40.50.300 1 243 2.9E-76 T 30-10-2018 CL1_0889 b332e8ee308e5961128c8d3ccb728595 372 SUPERFAMILY SSF52540 5 249 5.18E-89 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_0889 b332e8ee308e5961128c8d3ccb728595 372 Gene3D G3DSA:2.40.50.100 245 304 4.1E-24 T 30-10-2018 CL1_0293 2912bd90d1de069c80758e56cf0d3b1a 391 SUPERFAMILY SSF54631 4 123 3.28E-17 T 30-10-2018 CL1_0293 2912bd90d1de069c80758e56cf0d3b1a 391 Gene3D G3DSA:3.10.580.10 4 122 1.9E-15 T 30-10-2018 CL1_0293 2912bd90d1de069c80758e56cf0d3b1a 391 PIRSF PIRSF036983 2 390 3.5E-141 T 30-10-2018 IPR014651 Uncharacterised conserved protein, 2xCBS, MJ1404 type CL1_0293 2912bd90d1de069c80758e56cf0d3b1a 391 Pfam PF00571 CBS domain 69 122 4.6E-4 T 30-10-2018 IPR000644 CBS domain CL1_0293 2912bd90d1de069c80758e56cf0d3b1a 391 Pfam PF00571 CBS domain 211 261 6.5E-13 T 30-10-2018 IPR000644 CBS domain CL1_0293 2912bd90d1de069c80758e56cf0d3b1a 391 Pfam PF00571 CBS domain 6 54 0.0069 T 30-10-2018 IPR000644 CBS domain CL1_0293 2912bd90d1de069c80758e56cf0d3b1a 391 Pfam PF00571 CBS domain 132 183 1.4E-16 T 30-10-2018 IPR000644 CBS domain CL1_0293 2912bd90d1de069c80758e56cf0d3b1a 391 SUPERFAMILY SSF54631 127 261 1.94E-35 T 30-10-2018 CL1_0293 2912bd90d1de069c80758e56cf0d3b1a 391 Gene3D G3DSA:3.10.580.10 123 204 9.4E-18 T 30-10-2018 CL1_0293 2912bd90d1de069c80758e56cf0d3b1a 391 Gene3D G3DSA:3.10.580.10 205 299 1.6E-16 T 30-10-2018 CL1_0293 2912bd90d1de069c80758e56cf0d3b1a 391 SMART SM00116 75 123 0.24 T 30-10-2018 IPR000644 CBS domain CL1_0293 2912bd90d1de069c80758e56cf0d3b1a 391 SMART SM00116 217 265 1.7E-9 T 30-10-2018 IPR000644 CBS domain CL1_0293 2912bd90d1de069c80758e56cf0d3b1a 391 SMART SM00116 139 187 6.9E-10 T 30-10-2018 IPR000644 CBS domain CL1_1016 9263c53e5e910ad3094df70f5b27803a 317 PIRSF PIRSF002849 1 316 3.7E-141 T 30-10-2018 CL1_1016 9263c53e5e910ad3094df70f5b27803a 317 Gene3D G3DSA:1.10.8.300 202 311 5.7E-38 T 30-10-2018 CL1_1016 9263c53e5e910ad3094df70f5b27803a 317 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 40 170 2.8E-68 T 30-10-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 CL1_1016 9263c53e5e910ad3094df70f5b27803a 317 Gene3D G3DSA:3.40.50.300 21 187 3.8E-49 T 30-10-2018 CL1_1016 9263c53e5e910ad3094df70f5b27803a 317 SUPERFAMILY SSF52540 15 287 5.2E-49 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_1653 a9ea9bd6fb106eeb2e28eee3befa2bbc 236 Gene3D G3DSA:2.40.50.580 3 80 5.8E-25 T 30-10-2018 CL1_1653 a9ea9bd6fb106eeb2e28eee3befa2bbc 236 TIGRFAM TIGR00230 sfsA: sugar fermentation stimulation protein 9 234 3.5E-53 T 30-10-2018 IPR005224 Sugar fermentation stimulation protein CL1_1653 a9ea9bd6fb106eeb2e28eee3befa2bbc 236 Gene3D G3DSA:3.40.1350.60 81 235 9.0E-42 T 30-10-2018 CL1_1653 a9ea9bd6fb106eeb2e28eee3befa2bbc 236 Hamap MF_00095 Sugar fermentation stimulation protein A [sfsA]. 5 235 38.669 T 30-10-2018 IPR005224 Sugar fermentation stimulation protein CL1_1653 a9ea9bd6fb106eeb2e28eee3befa2bbc 236 Pfam PF03749 Sugar fermentation stimulation protein 16 222 2.9E-49 T 30-10-2018 IPR005224 Sugar fermentation stimulation protein CL1_0870 d28eab9ecf5263c19699575130d2094f 275 SUPERFAMILY SSF103481 39 133 1.09E-11 T 30-10-2018 CL1_0870 d28eab9ecf5263c19699575130d2094f 275 Pfam PF00892 EamA-like transporter family 5 131 1.7E-19 T 30-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CL1_0870 d28eab9ecf5263c19699575130d2094f 275 Pfam PF00892 EamA-like transporter family 139 269 8.2E-18 T 30-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CL1_0870 d28eab9ecf5263c19699575130d2094f 275 SUPERFAMILY SSF103481 176 269 2.35E-14 T 30-10-2018 CL1_1649 5ab7d6aff26913e927ed547f42a982df 652 Pfam PF13307 Helicase C-terminal domain 449 620 6.5E-37 T 30-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 CL1_1649 5ab7d6aff26913e927ed547f42a982df 652 Gene3D G3DSA:3.40.50.300 24 403 2.7E-114 T 30-10-2018 CL1_1649 5ab7d6aff26913e927ed547f42a982df 652 SMART SM00491 466 608 2.7E-45 T 30-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 CL1_1649 5ab7d6aff26913e927ed547f42a982df 652 SMART SM00487 12 270 7.7E-8 T 30-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CL1_1649 5ab7d6aff26913e927ed547f42a982df 652 Gene3D G3DSA:3.40.50.300 418 632 1.6E-41 T 30-10-2018 CL1_1649 5ab7d6aff26913e927ed547f42a982df 652 Gene3D G3DSA:1.10.275.40 234 371 2.7E-114 T 30-10-2018 CL1_1649 5ab7d6aff26913e927ed547f42a982df 652 SUPERFAMILY SSF52540 6 235 1.09E-17 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_1649 5ab7d6aff26913e927ed547f42a982df 652 TIGRFAM TIGR00604 rad3: DNA repair helicase (rad3) 328 632 7.3E-78 T 30-10-2018 IPR013020 ATP-dependent helicase Rad3/Chl1-like GO:0004003 CL1_1649 5ab7d6aff26913e927ed547f42a982df 652 Gene3D G3DSA:1.10.30.20 99 175 2.7E-114 T 30-10-2018 CL1_1649 5ab7d6aff26913e927ed547f42a982df 652 Pfam PF06733 DEAD_2 68 238 9.4E-34 T 30-10-2018 IPR010614 DEAD2 GO:0003677|GO:0004003|GO:0005524 CL1_1649 5ab7d6aff26913e927ed547f42a982df 652 SMART SM00488 7 258 5.9E-76 T 30-10-2018 IPR006554 Helicase-like, DEXD box c2 type GO:0004003|GO:0016818 CL1_1649 5ab7d6aff26913e927ed547f42a982df 652 Pfam PF06777 Helical and beta-bridge domain 244 435 8.6E-65 T 30-10-2018 IPR010643 Helical and beta-bridge domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167246|Reactome: R-HSA-2564830|Reactome: R-HSA-427413|Reactome: R-HSA-5696395|Reactome: R-HSA-5696400|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73863|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-77075 CL1_0184 6588c7d22cef785fde111d83416388f8 377 TIGRFAM TIGR00236 wecB: UDP-N-acetylglucosamine 2-epimerase 5 361 2.4E-129 T 30-10-2018 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 CL1_0184 6588c7d22cef785fde111d83416388f8 377 Gene3D G3DSA:3.40.50.2000 183 347 1.0E-135 T 30-10-2018 CL1_0184 6588c7d22cef785fde111d83416388f8 377 SUPERFAMILY SSF53756 4 365 2.93E-123 T 30-10-2018 CL1_0184 6588c7d22cef785fde111d83416388f8 377 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 26 360 3.4E-118 T 30-10-2018 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 CL1_0184 6588c7d22cef785fde111d83416388f8 377 Gene3D G3DSA:3.40.50.2000 6 357 1.0E-135 T 30-10-2018 CL1_0108 f6e881ed1909cf835e1401ea6183d693 89 SUPERFAMILY SSF46785 4 49 1.14E-5 T 30-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CL1_0108 f6e881ed1909cf835e1401ea6183d693 89 Gene3D G3DSA:1.10.10.10 2 51 2.9E-6 T 30-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CL1_1445 a7c3c458aae29a5c436900add340c09d 81 Gene3D G3DSA:3.30.70.920 2 74 4.3E-21 T 30-10-2018 CL1_1445 a7c3c458aae29a5c436900add340c09d 81 SUPERFAMILY SSF54909 2 76 1.88E-16 T 30-10-2018 IPR011008 Dimeric alpha-beta barrel CL1_1445 a7c3c458aae29a5c436900add340c09d 81 Pfam PF01037 Lrp/AsnC ligand binding domain 6 76 5.8E-16 T 30-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CL1_0421 b13be169ac97c7104c513609abd75dbd 250 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 14 95 1.1E-14 T 30-10-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 CL1_0421 b13be169ac97c7104c513609abd75dbd 250 SUPERFAMILY SSF51695 10 231 7.06E-35 T 30-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 CL1_0421 b13be169ac97c7104c513609abd75dbd 250 Gene3D G3DSA:3.20.20.190 4 239 6.0E-41 T 30-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 CL1_1976 6fa02772f192baeb567e46c4b07def48 311 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 83 97 1.7E-23 T 30-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase CL1_1976 6fa02772f192baeb567e46c4b07def48 311 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 228 244 1.7E-23 T 30-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase CL1_1976 6fa02772f192baeb567e46c4b07def48 311 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 112 122 1.7E-23 T 30-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase CL1_1976 6fa02772f192baeb567e46c4b07def48 311 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 178 190 1.7E-23 T 30-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase CL1_1976 6fa02772f192baeb567e46c4b07def48 311 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 289 306 1.7E-23 T 30-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase CL1_1976 6fa02772f192baeb567e46c4b07def48 311 Pfam PF17125 N-terminal domain of 16S rRNA methyltransferase RsmF 13 97 4.3E-17 T 30-10-2018 IPR031341 Ribosomal RNA small subunit methyltransferase F, N-terminal Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 CL1_1976 6fa02772f192baeb567e46c4b07def48 311 Pfam PF01189 16S rRNA methyltransferase RsmB/F 101 304 1.3E-51 T 30-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 CL1_1976 6fa02772f192baeb567e46c4b07def48 311 SUPERFAMILY SSF53335 21 306 2.43E-61 T 30-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CL1_1976 6fa02772f192baeb567e46c4b07def48 311 Gene3D G3DSA:3.40.50.150 101 311 4.8E-72 T 30-10-2018 CL1_1976 6fa02772f192baeb567e46c4b07def48 311 TIGRFAM TIGR00446 nop2p: NOL1/NOP2/sun family putative RNA methylase 39 306 3.4E-91 T 30-10-2018 IPR011023 Nop2p GO:0003723|GO:0006364|GO:0008757 Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 CL1_1976 6fa02772f192baeb567e46c4b07def48 311 Gene3D G3DSA:3.30.70.3130 4 96 1.6E-17 T 30-10-2018 CL1_0223 a2820ce74e5d012a4f78ef7bf786c778 440 Pfam PF06068 TIP49 C-terminus 14 403 1.3E-160 T 30-10-2018 IPR010339 TIP49, C-terminal GO:0003678|GO:0005524 Reactome: R-HSA-171319|Reactome: R-HSA-3214847 CL1_0223 a2820ce74e5d012a4f78ef7bf786c778 440 SUPERFAMILY SSF50249 126 207 6.34E-20 T 30-10-2018 IPR012340 Nucleic acid-binding, OB-fold CL1_0223 a2820ce74e5d012a4f78ef7bf786c778 440 SUPERFAMILY SSF52540 37 423 1.82E-40 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_0223 a2820ce74e5d012a4f78ef7bf786c778 440 Gene3D G3DSA:1.10.8.60 354 438 1.3E-25 T 30-10-2018 CL1_0223 a2820ce74e5d012a4f78ef7bf786c778 440 Gene3D G3DSA:3.40.50.300 18 349 8.3E-113 T 30-10-2018 CL1_0223 a2820ce74e5d012a4f78ef7bf786c778 440 SMART SM00382 62 353 8.2E-12 T 30-10-2018 IPR003593 AAA+ ATPase domain CL1_0223 a2820ce74e5d012a4f78ef7bf786c778 440 Gene3D G3DSA:2.40.50.360 119 243 8.3E-113 T 30-10-2018 CL1_1140 0b67dc2cca043a5504171d3c0ffbda9d 121 TIGRFAM TIGR01300 CPA3_mnhG_phaG: monovalent cation/proton antiporter, MnhG/PhaG subunit 9 112 1.8E-35 T 30-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 CL1_1140 0b67dc2cca043a5504171d3c0ffbda9d 121 Pfam PF03334 Na+/H+ antiporter subunit 9 98 5.8E-23 T 30-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 CL1_1818 aff6d6420fa7614fa426ad5504d2be8d 237 Pfam PF01881 CRISPR associated protein Cas6 83 233 6.4E-22 T 30-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 CL1_1818 aff6d6420fa7614fa426ad5504d2be8d 237 Gene3D G3DSA:3.30.70.1900 105 235 4.1E-10 T 30-10-2018 CL1_1818 aff6d6420fa7614fa426ad5504d2be8d 237 TIGRFAM TIGR01877 cas_cas6: CRISPR-associated endoribonuclease Cas6 38 233 5.3E-33 T 30-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 CL1_1818 aff6d6420fa7614fa426ad5504d2be8d 237 Gene3D G3DSA:3.30.70.1890 1 104 6.0E-7 T 30-10-2018 CL1_1818 aff6d6420fa7614fa426ad5504d2be8d 237 PIRSF PIRSF005054 1 237 1.0E-37 T 30-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 CL1_1403 6a488278a9dd7260629a9ca1a5a4fa26 350 SUPERFAMILY SSF53901 174 348 4.8E-45 T 30-10-2018 IPR016039 Thiolase-like GO:0003824 CL1_1403 6a488278a9dd7260629a9ca1a5a4fa26 350 SUPERFAMILY SSF53901 11 169 1.48E-32 T 30-10-2018 IPR016039 Thiolase-like GO:0003824 CL1_1403 6a488278a9dd7260629a9ca1a5a4fa26 350 Hamap MF_01409 UPF0219 protein . 10 350 60.757 T 30-10-2018 IPR004656 Putative condensing enzyme FabH-related CL1_1403 6a488278a9dd7260629a9ca1a5a4fa26 350 TIGRFAM TIGR00748 HMG_CoA_syn_Arc: putative hydroxymethylglutaryl-CoA synthase 11 350 3.2E-192 T 30-10-2018 IPR004656 Putative condensing enzyme FabH-related CL1_1403 6a488278a9dd7260629a9ca1a5a4fa26 350 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 223 303 2.5E-9 T 30-10-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CL1_1403 6a488278a9dd7260629a9ca1a5a4fa26 350 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 110 171 2.5E-4 T 30-10-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CL1_1403 6a488278a9dd7260629a9ca1a5a4fa26 350 Gene3D G3DSA:3.40.47.10 9 349 1.2E-70 T 30-10-2018 IPR016039 Thiolase-like GO:0003824 CL1_1648 7bb62d4232b4a9f943b3b59622691682 203 Gene3D G3DSA:1.20.1540.10 4 199 9.6E-37 T 30-10-2018 IPR035952 Rhomboid-like superfamily CL1_1648 7bb62d4232b4a9f943b3b59622691682 203 SUPERFAMILY SSF144091 9 193 6.02E-39 T 30-10-2018 CL1_1648 7bb62d4232b4a9f943b3b59622691682 203 Pfam PF01694 Rhomboid family 56 191 3.7E-30 T 30-10-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 CL1_0977 540dbf3e94e2c0342d5ad9af93472619 391 Pfam PF00999 Sodium/hydrogen exchanger family 9 382 1.9E-58 T 30-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 CL1_0977 540dbf3e94e2c0342d5ad9af93472619 391 Gene3D G3DSA:1.20.1530.20 1 391 2.2E-77 T 30-10-2018 IPR038770 Sodium/solute symporter superfamily CL1_0561 b8e38ad4ff1ff0aef668845d70841248 510 PRINTS PR01036 Tetracycline resistance protein TetB signature 94 114 1.6E-5 T 30-10-2018 CL1_0561 b8e38ad4ff1ff0aef668845d70841248 510 PRINTS PR01036 Tetracycline resistance protein TetB signature 124 148 1.6E-5 T 30-10-2018 CL1_0561 b8e38ad4ff1ff0aef668845d70841248 510 PRINTS PR01036 Tetracycline resistance protein TetB signature 149 173 1.6E-5 T 30-10-2018 CL1_0561 b8e38ad4ff1ff0aef668845d70841248 510 PRINTS PR01036 Tetracycline resistance protein TetB signature 62 84 1.6E-5 T 30-10-2018 CL1_0561 b8e38ad4ff1ff0aef668845d70841248 510 SUPERFAMILY SSF103473 2 492 5.1E-57 T 30-10-2018 IPR036259 MFS transporter superfamily CL1_0561 b8e38ad4ff1ff0aef668845d70841248 510 Gene3D G3DSA:1.20.1720.10 1 207 1.1E-36 T 30-10-2018 CL1_0561 b8e38ad4ff1ff0aef668845d70841248 510 Gene3D G3DSA:1.20.1720.10 212 417 6.6E-13 T 30-10-2018 CL1_0561 b8e38ad4ff1ff0aef668845d70841248 510 Pfam PF07690 Major Facilitator Superfamily 5 397 8.1E-43 T 30-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CL1_1035 799634bc8c5caced7ce0ac801a9587b3 383 SUPERFAMILY SSF52374 4 368 5.63E-91 T 30-10-2018 CL1_1035 799634bc8c5caced7ce0ac801a9587b3 383 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 72 378 1.3E-105 T 30-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CL1_1035 799634bc8c5caced7ce0ac801a9587b3 383 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 85 101 1.5E-20 T 30-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CL1_1035 799634bc8c5caced7ce0ac801a9587b3 383 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 252 262 1.5E-20 T 30-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CL1_1035 799634bc8c5caced7ce0ac801a9587b3 383 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 208 229 1.5E-20 T 30-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CL1_1035 799634bc8c5caced7ce0ac801a9587b3 383 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 138 157 1.5E-20 T 30-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CL1_1035 799634bc8c5caced7ce0ac801a9587b3 383 Pfam PF00579 tRNA synthetases class I (W and Y) 73 347 6.0E-25 T 30-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 CL1_1035 799634bc8c5caced7ce0ac801a9587b3 383 Gene3D G3DSA:1.10.240.10 256 381 2.9E-44 T 30-10-2018 CL1_1035 799634bc8c5caced7ce0ac801a9587b3 383 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 81 90 - T 30-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CL1_1035 799634bc8c5caced7ce0ac801a9587b3 383 Gene3D G3DSA:3.40.50.620 1 255 3.1E-103 T 30-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CL1_1035 799634bc8c5caced7ce0ac801a9587b3 383 Hamap MF_00140_A Tryptophan--tRNA ligase [trpS]. 5 366 46.273 T 30-10-2018 IPR020653 Tryptophan-tRNA ligase, archaea GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CL1_1498 4c0b54c0584f4245d5b4202465ff686e 222 Gene3D G3DSA:3.30.2010.10 109 201 6.1E-19 T 30-10-2018 CL1_1498 4c0b54c0584f4245d5b4202465ff686e 222 Pfam PF01863 Protein of unknown function DUF45 11 197 5.9E-48 T 30-10-2018 IPR002725 Protein of unknown function DUF45 CL1_1408 9d504e46f4374145df5abf37a8b23a6c 177 SMART SM00530 90 145 2.6E-5 T 30-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CL1_1408 9d504e46f4374145df5abf37a8b23a6c 177 TIGRFAM TIGR00270 TIGR00270: TIGR00270 family protein 8 171 5.0E-23 T 30-10-2018 IPR004451 Conserved hypothetical protein CHP00270 CL1_1408 9d504e46f4374145df5abf37a8b23a6c 177 Gene3D G3DSA:1.10.260.40 79 177 1.2E-10 T 30-10-2018 CL1_1408 9d504e46f4374145df5abf37a8b23a6c 177 SUPERFAMILY SSF47413 80 143 6.22E-7 T 30-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 CL1_1408 9d504e46f4374145df5abf37a8b23a6c 177 Pfam PF01381 Helix-turn-helix 93 142 1.3E-5 T 30-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CL1_1505 d9726c126f091842c8f3c1200b5affc2 140 Gene3D G3DSA:2.60.120.460 1 132 4.0E-46 T 30-10-2018 IPR035917 YjbQ-like superfamily CL1_1505 d9726c126f091842c8f3c1200b5affc2 140 SUPERFAMILY SSF111038 3 131 2.75E-38 T 30-10-2018 IPR035917 YjbQ-like superfamily CL1_1505 d9726c126f091842c8f3c1200b5affc2 140 TIGRFAM TIGR00149 TIGR00149_YjbQ: secondary thiamine-phosphate synthase enzyme 4 131 2.2E-38 T 30-10-2018 IPR001602 Uncharacterised protein family UPF0047 CL1_1505 d9726c126f091842c8f3c1200b5affc2 140 Pfam PF01894 Uncharacterised protein family UPF0047 17 130 2.8E-35 T 30-10-2018 IPR001602 Uncharacterised protein family UPF0047 CL1_1505 d9726c126f091842c8f3c1200b5affc2 140 PIRSF PIRSF004681 2 133 9.9E-37 T 30-10-2018 IPR001602 Uncharacterised protein family UPF0047 CL1_0351 ef6da2e17394df958204abe7a036f532 95 SUPERFAMILY SSF158372 5 85 2.88E-26 T 30-10-2018 IPR036809 AF1782-like superfamily CL1_0351 ef6da2e17394df958204abe7a036f532 95 Gene3D G3DSA:1.20.1270.90 5 85 4.7E-25 T 30-10-2018 CL1_0351 ef6da2e17394df958204abe7a036f532 95 Pfam PF04010 Protein of unknown function (DUF357) 12 84 9.4E-30 T 30-10-2018 IPR023140 Domain of unknown function DUF357 CL1_0230 74ac2e62cf80f8d7554977f5f27b2da8 212 SUPERFAMILY SSF52954 1 192 3.01E-34 T 30-10-2018 CL1_0230 74ac2e62cf80f8d7554977f5f27b2da8 212 SMART SM00879 2 189 1.6E-14 T 30-10-2018 IPR007109 Brix domain CL1_0230 74ac2e62cf80f8d7554977f5f27b2da8 212 Gene3D G3DSA:3.40.50.10480 1 185 1.9E-32 T 30-10-2018 CL1_0230 74ac2e62cf80f8d7554977f5f27b2da8 212 Hamap MF_00699 Probable Brix domain-containing ribosomal biogenesis protein. 1 190 29.422 T 30-10-2018 IPR023548 Probable Brix domain-containing ribosomal biogenesis protein CL1_0910 a503277b7f911f46244b8fbe536b5af8 285 SUPERFAMILY SSF103481 180 277 3.4E-18 T 30-10-2018 CL1_0910 a503277b7f911f46244b8fbe536b5af8 285 SUPERFAMILY SSF103481 38 140 4.18E-14 T 30-10-2018 CL1_0910 a503277b7f911f46244b8fbe536b5af8 285 Pfam PF00892 EamA-like transporter family 147 273 4.3E-26 T 30-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CL1_0910 a503277b7f911f46244b8fbe536b5af8 285 Pfam PF00892 EamA-like transporter family 3 137 3.5E-24 T 30-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CL1_1907 d512d7de25fb7a74b009d25e1d5f4354 382 Gene3D G3DSA:3.40.50.150 41 235 1.8E-24 T 30-10-2018 CL1_1907 d512d7de25fb7a74b009d25e1d5f4354 382 SUPERFAMILY SSF53335 58 159 5.08E-18 T 30-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CL1_1907 d512d7de25fb7a74b009d25e1d5f4354 382 Pfam PF13649 Methyltransferase domain 87 150 5.6E-7 T 30-10-2018 CL1_1875 7c075b54d032e6ceba04010916b6634f 191 SUPERFAMILY SSF48317 25 185 4.19E-26 T 30-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily CL1_1875 7c075b54d032e6ceba04010916b6634f 191 SMART SM00014 80 183 0.0046 T 30-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CL1_1875 7c075b54d032e6ceba04010916b6634f 191 Pfam PF01569 PAP2 superfamily 84 177 3.6E-10 T 30-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CL1_1875 7c075b54d032e6ceba04010916b6634f 191 Gene3D G3DSA:1.20.144.10 9 112 7.1E-6 T 30-10-2018 CL1_1875 7c075b54d032e6ceba04010916b6634f 191 Gene3D G3DSA:1.20.144.10 113 189 1.5E-10 T 30-10-2018 CL1_0357 29e2aa5bf0773902890b174cb1ec702a 685 Pfam PF05753 Translocon-associated protein beta (TRAPB) 350 448 7.6E-7 T 30-10-2018 CL1_0972 d2f25abea430f05721e5caf78f6e03ff 652 ProDom PD014405 HYDROLASE METABOLISM CARBOHYDRATE GLYCOSIDASE ALPHA-AMYLASE TRANSFERASE 4-ALPHA-GLUCANOTRANSFERASE GLYCOSYLTRANSFERASE FAMILY DIRECT 317 382 7.0E-31 T 30-10-2018 IPR015178 Alpha-amylase/4-alpha-glucanotransferase, central domain CL1_0972 d2f25abea430f05721e5caf78f6e03ff 652 SUPERFAMILY SSF88713 3 307 5.93E-69 T 30-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CL1_0972 d2f25abea430f05721e5caf78f6e03ff 652 Gene3D G3DSA:3.20.110.20 1 379 3.5E-176 T 30-10-2018 CL1_0972 d2f25abea430f05721e5caf78f6e03ff 652 Pfam PF09095 Domain of unknown function (DUF1926) 390 647 1.1E-76 T 30-10-2018 IPR015179 Alpha-amylase/4-alpha-glucanotransferase, C-terminal GO:0003824|GO:0005975|GO:0030246 CL1_0972 d2f25abea430f05721e5caf78f6e03ff 652 Pfam PF03065 Glycosyl hydrolase family 57 5 288 5.6E-64 T 30-10-2018 IPR004300 Glycoside hydrolase family 57, N-terminal domain GO:0003824|GO:0005975 CL1_0972 d2f25abea430f05721e5caf78f6e03ff 652 Pfam PF09094 Domain of unknown function (DUF1925) 309 381 2.7E-37 T 30-10-2018 IPR015178 Alpha-amylase/4-alpha-glucanotransferase, central domain CL1_0972 d2f25abea430f05721e5caf78f6e03ff 652 SUPERFAMILY SSF74650 387 651 5.65E-98 T 30-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 CL1_0972 d2f25abea430f05721e5caf78f6e03ff 652 Gene3D G3DSA:2.70.98.10 386 652 1.4E-86 T 30-10-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 CL1_0972 d2f25abea430f05721e5caf78f6e03ff 652 SUPERFAMILY SSF88688 309 381 2.42E-37 T 30-10-2018 IPR028995 Glycoside hydrolase families 57/38, central domain superfamily CL1_1282 cadcf666655395177fce182bab9242d3 261 PIRSF PIRSF005956 1 259 4.5E-99 T 30-10-2018 IPR005137 Membrane complex biogenesis protein, BtpA family CL1_1282 cadcf666655395177fce182bab9242d3 261 SUPERFAMILY SSF51366 11 251 1.35E-26 T 30-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 CL1_1282 cadcf666655395177fce182bab9242d3 261 Pfam PF03437 BtpA family 5 254 1.2E-107 T 30-10-2018 IPR005137 Membrane complex biogenesis protein, BtpA family CL1_1282 cadcf666655395177fce182bab9242d3 261 ProDom PD011184 BTPA I PHOTOSYSTEM BIOGENESIS ASSEMBLY SGCQ TRIPHOSPHATASE NUCLEOSIDE PAE3553 ENZYME 28 199 2.0E-72 T 30-10-2018 IPR005137 Membrane complex biogenesis protein, BtpA family CL1_1282 cadcf666655395177fce182bab9242d3 261 TIGRFAM TIGR00259 thylakoid_BtpA: membrane complex biogenesis protein, BtpA family 6 256 3.3E-109 T 30-10-2018 IPR005137 Membrane complex biogenesis protein, BtpA family CL1_0447 52412e521c4fabc66be368e90456e31b 375 Gene3D G3DSA:3.40.720.10 1 373 1.4E-55 T 30-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 CL1_0447 52412e521c4fabc66be368e90456e31b 375 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 6 322 1.4E-47 T 30-10-2018 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 CL1_0447 52412e521c4fabc66be368e90456e31b 375 SUPERFAMILY SSF53649 1 359 1.35E-75 T 30-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 CL1_0092 5dfc5b0d9ab03a3290fcbcb613de7876 76 SUPERFAMILY SSF50182 5 74 7.8E-18 T 30-10-2018 IPR010920 LSM domain superfamily CL1_0092 5dfc5b0d9ab03a3290fcbcb613de7876 76 SMART SM00651 7 72 3.6E-19 T 30-10-2018 IPR001163 LSM domain, eukaryotic/archaea-type CL1_0092 5dfc5b0d9ab03a3290fcbcb613de7876 76 Pfam PF01423 LSM domain 9 72 6.4E-19 T 30-10-2018 IPR001163 LSM domain, eukaryotic/archaea-type CL1_0092 5dfc5b0d9ab03a3290fcbcb613de7876 76 Hamap MF_00257 Putative snRNP Sm-like protein. 1 72 25.149 T 30-10-2018 IPR022901 snRNP Sm-like, putative, archaea CL1_0092 5dfc5b0d9ab03a3290fcbcb613de7876 76 Gene3D G3DSA:2.30.30.100 1 74 1.0E-22 T 30-10-2018 CL1_0088 d2e8f0cca98f95507b2b81cbc5455803 202 Gene3D G3DSA:3.40.1280.10 1 200 7.4E-69 T 30-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CL1_0088 d2e8f0cca98f95507b2b81cbc5455803 202 SUPERFAMILY SSF75217 1 198 3.66E-66 T 30-10-2018 IPR029028 Alpha/beta knot methyltransferases CL1_0088 d2e8f0cca98f95507b2b81cbc5455803 202 Hamap MF_00587 tRNA (pseudouridine(54)-N(1))-methyltransferase [trmY]. 1 199 36.854 T 30-10-2018 IPR007158 tRNA (pseudouridine(54)-N(1))-methyltransferase, TrmY GO:0008175 CL1_0088 d2e8f0cca98f95507b2b81cbc5455803 202 Pfam PF04013 Putative SAM-dependent RNA methyltransferase 1 197 1.4E-50 T 30-10-2018 IPR007158 tRNA (pseudouridine(54)-N(1))-methyltransferase, TrmY GO:0008175 CL1_0706 dd44ef40e0e10a8c7d77567d7b2a6db1 281 Gene3D G3DSA:3.20.20.150 13 281 3.7E-39 T 30-10-2018 CL1_0706 dd44ef40e0e10a8c7d77567d7b2a6db1 281 SMART SM00518 4 276 5.8E-86 T 30-10-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 CL1_0706 dd44ef40e0e10a8c7d77567d7b2a6db1 281 SUPERFAMILY SSF51658 7 278 2.8E-60 T 30-10-2018 IPR036237 Xylose isomerase-like superfamily CL1_0706 dd44ef40e0e10a8c7d77567d7b2a6db1 281 Pfam PF01261 Xylose isomerase-like TIM barrel 30 239 1.2E-19 T 30-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CL1_0590 3f7858aefedea72e594f07b5bd656bd5 135 ProSitePatterns PS00360 Ribosomal protein S9 signature. 68 86 - T 30-10-2018 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 CL1_0590 3f7858aefedea72e594f07b5bd656bd5 135 Gene3D G3DSA:3.30.230.10 1 135 6.8E-51 T 30-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CL1_0590 3f7858aefedea72e594f07b5bd656bd5 135 Pfam PF00380 Ribosomal protein S9/S16 8 135 1.6E-30 T 30-10-2018 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 CL1_0590 3f7858aefedea72e594f07b5bd656bd5 135 SUPERFAMILY SSF54211 3 135 4.55E-34 T 30-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CL1_0590 3f7858aefedea72e594f07b5bd656bd5 135 Hamap MF_00532_A 30S ribosomal protein S9 [rpsI]. 3 135 37.159 T 30-10-2018 IPR019958 Ribosomal protein S9, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 CL1_0590 3f7858aefedea72e594f07b5bd656bd5 135 TIGRFAM TIGR03627 uS9_arch: ribosomal protein uS9 3 135 7.7E-62 T 30-10-2018 IPR019958 Ribosomal protein S9, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 CL1_1224 3e59c3daff3547b00d28152418e26443 199 Pfam PF08241 Methyltransferase domain 41 134 2.5E-25 T 30-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 CL1_1224 3e59c3daff3547b00d28152418e26443 199 SUPERFAMILY SSF53335 10 188 4.37E-38 T 30-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CL1_1224 3e59c3daff3547b00d28152418e26443 199 Gene3D G3DSA:3.40.50.150 6 187 1.0E-36 T 30-10-2018 CL1_1224 3e59c3daff3547b00d28152418e26443 199 ProSitePatterns PS01184 ubiE/COQ5 methyltransferase family signature 2. 125 139 - T 30-10-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 CL1_0029 de68cc8d07a564efdc0e3999905f0c96 451 SUPERFAMILY SSF52374 1 289 2.82E-106 T 30-10-2018 CL1_0029 de68cc8d07a564efdc0e3999905f0c96 451 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 1 289 6.0E-135 T 30-10-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 CL1_0029 de68cc8d07a564efdc0e3999905f0c96 451 Pfam PF09190 DALR domain 331 390 6.5E-17 T 30-10-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 CL1_0029 de68cc8d07a564efdc0e3999905f0c96 451 Gene3D G3DSA:3.40.50.620 1 280 1.2E-140 T 30-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CL1_0029 de68cc8d07a564efdc0e3999905f0c96 451 SUPERFAMILY SSF47323 291 448 1.24E-35 T 30-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CL1_0029 de68cc8d07a564efdc0e3999905f0c96 451 SMART SM00840 331 392 7.1E-16 T 30-10-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 CL1_0029 de68cc8d07a564efdc0e3999905f0c96 451 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 1 448 1.4E-169 T 30-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 CL1_0029 de68cc8d07a564efdc0e3999905f0c96 451 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 1 12 2.6E-30 T 30-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CL1_0029 de68cc8d07a564efdc0e3999905f0c96 451 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 197 218 2.6E-30 T 30-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CL1_0029 de68cc8d07a564efdc0e3999905f0c96 451 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 166 184 2.6E-30 T 30-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CL1_0029 de68cc8d07a564efdc0e3999905f0c96 451 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 37 46 2.6E-30 T 30-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CL1_0029 de68cc8d07a564efdc0e3999905f0c96 451 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 1 449 36.369 T 30-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 CL1_0029 de68cc8d07a564efdc0e3999905f0c96 451 Gene3D G3DSA:1.20.120.640 281 448 6.5E-38 T 30-10-2018 CL1_0695 4281b1b3a00acbdd6844226452ea0021 340 SUPERFAMILY SSF160945 101 336 4.18E-89 T 30-10-2018 CL1_0695 4281b1b3a00acbdd6844226452ea0021 340 Gene3D G3DSA:3.40.50.10620 101 326 2.9E-66 T 30-10-2018 CL1_0695 4281b1b3a00acbdd6844226452ea0021 340 ProDom PD038575 MJECL12 PLASMID PH0156 102 324 4.0E-83 T 30-10-2018 IPR024508 Protein of unknown function DUF3226 CL1_0695 4281b1b3a00acbdd6844226452ea0021 340 Gene3D G3DSA:1.10.3490.10 237 325 2.9E-66 T 30-10-2018 CL1_0695 4281b1b3a00acbdd6844226452ea0021 340 Pfam PF11536 Protein of unknown function (DUF3226) 103 338 3.7E-80 T 30-10-2018 IPR024508 Protein of unknown function DUF3226 CL1_0340 e58d8607865482071eb34d0e63787ac5 130 SUPERFAMILY SSF88723 2 115 3.08E-7 T 30-10-2018 IPR029060 PIN-like domain superfamily CL1_0340 e58d8607865482071eb34d0e63787ac5 130 Pfam PF10130 PIN domain 1 112 1.4E-18 T 30-10-2018 IPR002716 PIN domain CL1_0639 4ee277c38aaaaf812cbb6b0e3b6a705e 600 Gene3D G3DSA:3.40.30.10 5 97 5.3E-21 T 30-10-2018 CL1_0639 4ee277c38aaaaf812cbb6b0e3b6a705e 600 SUPERFAMILY SSF54862 540 597 3.0E-15 T 30-10-2018 CL1_0639 4ee277c38aaaaf812cbb6b0e3b6a705e 600 SMART SM00928 439 484 3.2E-22 T 30-10-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CL1_0639 4ee277c38aaaaf812cbb6b0e3b6a705e 600 Gene3D G3DSA:3.40.50.11540 163 341 2.7E-83 T 30-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CL1_0639 4ee277c38aaaaf812cbb6b0e3b6a705e 600 SUPERFAMILY SSF140490 435 531 3.53E-36 T 30-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CL1_0639 4ee277c38aaaaf812cbb6b0e3b6a705e 600 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 440 524 8.8E-32 T 30-10-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CL1_0639 4ee277c38aaaaf812cbb6b0e3b6a705e 600 Pfam PF10531 SLBB domain 353 401 2.7E-9 T 30-10-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CL1_0639 4ee277c38aaaaf812cbb6b0e3b6a705e 600 Gene3D G3DSA:3.10.20.600 342 436 1.5E-32 T 30-10-2018 CL1_0639 4ee277c38aaaaf812cbb6b0e3b6a705e 600 SUPERFAMILY SSF52833 7 98 8.83E-20 T 30-10-2018 IPR036249 Thioredoxin-like superfamily CL1_0639 4ee277c38aaaaf812cbb6b0e3b6a705e 600 SUPERFAMILY SSF142019 112 350 5.1E-97 T 30-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CL1_0639 4ee277c38aaaaf812cbb6b0e3b6a705e 600 Gene3D G3DSA:3.30.70.20 540 593 2.9E-13 T 30-10-2018 CL1_0639 4ee277c38aaaaf812cbb6b0e3b6a705e 600 Pfam PF00037 4Fe-4S binding domain 540 563 8.6E-6 T 30-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CL1_0639 4ee277c38aaaaf812cbb6b0e3b6a705e 600 Pfam PF00037 4Fe-4S binding domain 571 593 1.3E-7 T 30-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CL1_0639 4ee277c38aaaaf812cbb6b0e3b6a705e 600 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 547 558 - T 30-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CL1_0639 4ee277c38aaaaf812cbb6b0e3b6a705e 600 SUPERFAMILY SSF142984 351 434 3.4E-25 T 30-10-2018 CL1_0639 4ee277c38aaaaf812cbb6b0e3b6a705e 600 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 159 329 1.8E-50 T 30-10-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CL1_0639 4ee277c38aaaaf812cbb6b0e3b6a705e 600 Gene3D G3DSA:1.20.1440.230 437 538 1.7E-33 T 30-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CL1_1173 8c7b995ae16e30e5d033eb0788df3c7d 987 SUPERFAMILY SSF50249 362 436 6.57E-6 T 30-10-2018 IPR012340 Nucleic acid-binding, OB-fold CL1_1173 8c7b995ae16e30e5d033eb0788df3c7d 987 Gene3D G3DSA:2.40.50.140 355 445 4.1E-5 T 30-10-2018 CL1_1173 8c7b995ae16e30e5d033eb0788df3c7d 987 Pfam PF01336 OB-fold nucleic acid binding domain 915 977 9.6E-8 T 30-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 CL1_1173 8c7b995ae16e30e5d033eb0788df3c7d 987 Gene3D G3DSA:2.40.50.140 894 986 7.8E-6 T 30-10-2018 CL1_1173 8c7b995ae16e30e5d033eb0788df3c7d 987 SUPERFAMILY SSF50249 914 984 1.27E-7 T 30-10-2018 IPR012340 Nucleic acid-binding, OB-fold CL1_0159 87243d608cdbf710b6616eba7a18c4bf 343 SMART SM00981 50 139 9.8E-23 T 30-10-2018 IPR004114 THUMP domain GO:0003723 CL1_0159 87243d608cdbf710b6616eba7a18c4bf 343 SUPERFAMILY SSF75217 177 326 3.4E-19 T 30-10-2018 IPR029028 Alpha/beta knot methyltransferases CL1_0159 87243d608cdbf710b6616eba7a18c4bf 343 Pfam PF14419 AF2226-like SPOUT RNA Methylase fused to THUMP 159 332 1.2E-81 T 30-10-2018 IPR025849 AF2226-like SPOUT RNA methylase fused to THUMP CL1_0159 87243d608cdbf710b6616eba7a18c4bf 343 Gene3D G3DSA:3.30.2130.30 1 140 1.3E-20 T 30-10-2018 CL1_0159 87243d608cdbf710b6616eba7a18c4bf 343 SUPERFAMILY SSF143437 1 137 3.14E-24 T 30-10-2018 CL1_0159 87243d608cdbf710b6616eba7a18c4bf 343 Pfam PF02926 THUMP domain 25 138 1.6E-27 T 30-10-2018 IPR004114 THUMP domain GO:0003723 CL1_0949 dc6e3e98db2aa8ea099d407b966efb65 210 Pfam PF03729 Short repeat of unknown function (DUF308) 116 166 0.02 T 30-10-2018 IPR005325 Protein of unknown function DUF308, membrane CL1_0949 dc6e3e98db2aa8ea099d407b966efb65 210 Pfam PF03729 Short repeat of unknown function (DUF308) 42 113 2.8E-9 T 30-10-2018 IPR005325 Protein of unknown function DUF308, membrane CL1_0832 45d39417d4475d265e34b0bb6be27742 317 SUPERFAMILY SSF52540 8 305 4.96E-34 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_0832 45d39417d4475d265e34b0bb6be27742 317 Gene3D G3DSA:3.40.50.300 6 312 2.9E-38 T 30-10-2018 CL1_0832 45d39417d4475d265e34b0bb6be27742 317 Pfam PF13469 Sulfotransferase family 10 250 6.6E-22 T 30-10-2018 CL1_1720 0eb9a3194be28597f92e05b9e502c581 909 SMART SM00331 661 909 1.6E-41 T 30-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CL1_1720 0eb9a3194be28597f92e05b9e502c581 909 Gene3D G3DSA:3.60.40.10 655 909 5.0E-71 T 30-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CL1_1720 0eb9a3194be28597f92e05b9e502c581 909 Pfam PF13672 Protein phosphatase 2C 673 872 1.7E-21 T 30-10-2018 CL1_1720 0eb9a3194be28597f92e05b9e502c581 909 SUPERFAMILY SSF81606 669 906 3.01E-65 T 30-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CL1_1720 0eb9a3194be28597f92e05b9e502c581 909 SMART SM00332 655 907 6.1E-36 T 30-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CL1_1375 c9559a3d38a380062f6eb6d9905e8d4f 581 SUPERFAMILY SSF56219 351 580 1.09E-30 T 30-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily CL1_1375 c9559a3d38a380062f6eb6d9905e8d4f 581 Gene3D G3DSA:3.60.10.10 353 581 5.6E-31 T 30-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily CL1_0273 7e450a33ce1540e3245679c63ec095c8 240 Pfam PF01522 Polysaccharide deacetylase 4 125 1.2E-19 T 30-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 CL1_0273 7e450a33ce1540e3245679c63ec095c8 240 SUPERFAMILY SSF88713 3 231 4.45E-34 T 30-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CL1_0273 7e450a33ce1540e3245679c63ec095c8 240 Gene3D G3DSA:3.20.20.370 1 237 8.4E-38 T 30-10-2018 CL1_0143 70e8c628bfde0b856589614d29ced132 264 Gene3D G3DSA:3.40.50.700 4 164 2.0E-41 T 30-10-2018 IPR037024 [NiFe]-hydrogenase, small subunit, N-terminal domain superfamily CL1_0143 70e8c628bfde0b856589614d29ced132 264 SUPERFAMILY SSF56770 4 211 5.23E-45 T 30-10-2018 CL1_0143 70e8c628bfde0b856589614d29ced132 264 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 16 150 2.0E-25 T 30-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CL1_1756 7b9fcd57fd3dbad696a96ccfe45bfc74 506 TIGRFAM TIGR00284 TIGR00284: dihydropteroate synthase-related protein 1 500 2.1E-93 T 30-10-2018 IPR005236 Dihydropteroate synthase-related protein synthase-related protein CL1_1756 7b9fcd57fd3dbad696a96ccfe45bfc74 506 Pfam PF00809 Pterin binding enzyme 170 236 5.6E-6 T 30-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CL1_1756 7b9fcd57fd3dbad696a96ccfe45bfc74 506 SUPERFAMILY SSF51717 158 382 2.09E-23 T 30-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CL1_1274 2eea0dd9e5bd2cd13f1760ec1e16a311 220 Pfam PF03192 Pyrococcus protein of unknown function, DUF257 10 209 1.7E-61 T 30-10-2018 IPR005489 Protein of unknown function DUF257 CL1_1274 2eea0dd9e5bd2cd13f1760ec1e16a311 220 Gene3D G3DSA:3.40.50.11570 4 215 3.6E-62 T 30-10-2018 CL1_1773 c3bdf08e31ffb07e9f0733dc487a82b4 180 Gene3D G3DSA:3.40.50.300 3 176 1.8E-41 T 30-10-2018 CL1_1773 c3bdf08e31ffb07e9f0733dc487a82b4 180 Pfam PF03266 NTPase 4 168 3.5E-55 T 30-10-2018 IPR004948 Nucleoside-triphosphatase, THEP1 type GO:0098519 KEGG: 00230+3.6.1.15|KEGG: 00730+3.6.1.15|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210 CL1_1773 c3bdf08e31ffb07e9f0733dc487a82b4 180 SUPERFAMILY SSF52540 5 150 4.2E-22 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_1773 c3bdf08e31ffb07e9f0733dc487a82b4 180 SMART SM00382 1 158 2.7E-5 T 30-10-2018 IPR003593 AAA+ ATPase domain CL1_1773 c3bdf08e31ffb07e9f0733dc487a82b4 180 Hamap MF_00796 Nucleoside-triphosphatase . 3 175 30.133 T 30-10-2018 IPR004948 Nucleoside-triphosphatase, THEP1 type GO:0098519 KEGG: 00230+3.6.1.15|KEGG: 00730+3.6.1.15|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210 CL1_1033 cec6c5568c2d8181470ef301f620f18e 225 SUPERFAMILY SSF56529 12 220 9.68E-79 T 30-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 CL1_1033 cec6c5568c2d8181470ef301f620f18e 225 Gene3D G3DSA:3.90.850.10 5 221 3.3E-90 T 30-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 CL1_1033 cec6c5568c2d8181470ef301f620f18e 225 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 17 217 1.7E-69 T 30-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 CL1_0147 997222525e77d5e005a9261303e3bb93 141 TIGRFAM TIGR00072 hydrog_prot: hydrogenase maturation protease 1 133 4.6E-26 T 30-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 CL1_0147 997222525e77d5e005a9261303e3bb93 141 Gene3D G3DSA:3.40.50.1450 1 136 2.1E-29 T 30-10-2018 IPR023430 Peptidase HybD-like domain superfamily CL1_0147 997222525e77d5e005a9261303e3bb93 141 SUPERFAMILY SSF53163 1 136 1.1E-24 T 30-10-2018 IPR023430 Peptidase HybD-like domain superfamily CL1_0147 997222525e77d5e005a9261303e3bb93 141 Pfam PF01750 Hydrogenase maturation protease 16 132 2.5E-20 T 30-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 CL1_0860 da09da3595cc81eaf1a56ce921078ee5 262 Gene3D G3DSA:3.40.50.1000 1 244 5.4E-90 T 30-10-2018 IPR023214 HAD superfamily CL1_0860 da09da3595cc81eaf1a56ce921078ee5 262 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 2 226 6.7E-43 T 30-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA CL1_0860 da09da3595cc81eaf1a56ce921078ee5 262 Pfam PF13344 Haloacid dehalogenase-like hydrolase 1 96 1.1E-24 T 30-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA CL1_0860 da09da3595cc81eaf1a56ce921078ee5 262 PIRSF PIRSF000915 1 256 8.3E-61 T 30-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA CL1_0860 da09da3595cc81eaf1a56ce921078ee5 262 Pfam PF13242 HAD-hyrolase-like 178 250 1.9E-19 T 30-10-2018 CL1_0860 da09da3595cc81eaf1a56ce921078ee5 262 Gene3D G3DSA:3.40.50.1000 62 178 5.4E-90 T 30-10-2018 IPR023214 HAD superfamily CL1_0860 da09da3595cc81eaf1a56ce921078ee5 262 SUPERFAMILY SSF56784 1 250 6.0E-65 T 30-10-2018 IPR036412 HAD-like superfamily CL1_0424 2102933f61faf59e9f5e759341ef7c01 495 Pfam PF01266 FAD dependent oxidoreductase 4 360 7.7E-69 T 30-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CL1_0424 2102933f61faf59e9f5e759341ef7c01 495 Gene3D G3DSA:1.10.10.1100 393 472 5.8E-18 T 30-10-2018 CL1_0424 2102933f61faf59e9f5e759341ef7c01 495 Gene3D G3DSA:3.50.50.60 5 355 1.4E-114 T 30-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily CL1_0424 2102933f61faf59e9f5e759341ef7c01 495 Pfam PF04324 BFD-like [2Fe-2S] binding domain 406 464 5.8E-16 T 30-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain CL1_0424 2102933f61faf59e9f5e759341ef7c01 495 SUPERFAMILY SSF51905 3 410 5.18E-58 T 30-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily CL1_0424 2102933f61faf59e9f5e759341ef7c01 495 SUPERFAMILY SSF54373 223 318 1.31E-7 T 30-10-2018 CL1_0424 2102933f61faf59e9f5e759341ef7c01 495 Gene3D G3DSA:3.30.9.10 90 321 1.4E-114 T 30-10-2018 CL1_0846 345d5f36584b81c642d37a59d40c647b 306 Gene3D G3DSA:3.40.50.300 14 180 2.6E-46 T 30-10-2018 CL1_0846 345d5f36584b81c642d37a59d40c647b 306 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 33 163 1.6E-61 T 30-10-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 CL1_0846 345d5f36584b81c642d37a59d40c647b 306 PIRSF PIRSF002849 1 306 5.3E-125 T 30-10-2018 CL1_0846 345d5f36584b81c642d37a59d40c647b 306 SMART SM00382 30 172 0.0012 T 30-10-2018 IPR003593 AAA+ ATPase domain CL1_0846 345d5f36584b81c642d37a59d40c647b 306 Gene3D G3DSA:1.10.8.300 193 301 4.9E-31 T 30-10-2018 CL1_0846 345d5f36584b81c642d37a59d40c647b 306 SUPERFAMILY SSF52540 3 276 1.67E-44 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_1329 daa2f6fd9cd2a50a78cbb4c918642f4a 526 SUPERFAMILY SSF48163 323 523 1.44E-49 T 30-10-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 CL1_1329 daa2f6fd9cd2a50a78cbb4c918642f4a 526 Gene3D G3DSA:1.10.10.860 271 318 2.3E-23 T 30-10-2018 CL1_1329 daa2f6fd9cd2a50a78cbb4c918642f4a 526 SUPERFAMILY SSF52374 3 319 5.9E-68 T 30-10-2018 CL1_1329 daa2f6fd9cd2a50a78cbb4c918642f4a 526 Hamap MF_00177 Lysine--tRNA ligase [lysS]. 2 526 38.359 T 30-10-2018 IPR002904 Lysine-tRNA ligase GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 CL1_1329 daa2f6fd9cd2a50a78cbb4c918642f4a 526 TIGRFAM TIGR00467 lysS_arch: lysine--tRNA ligase 2 523 1.2E-160 T 30-10-2018 IPR002904 Lysine-tRNA ligase GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 CL1_1329 daa2f6fd9cd2a50a78cbb4c918642f4a 526 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 30 39 - T 30-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CL1_1329 daa2f6fd9cd2a50a78cbb4c918642f4a 526 Gene3D G3DSA:2.30.30.300 170 213 2.2E-111 T 30-10-2018 IPR023386 Lysine-tRNA ligase, insertion domain superfamily GO:0004824 KEGG: 00970+6.1.1.6 CL1_1329 daa2f6fd9cd2a50a78cbb4c918642f4a 526 Gene3D G3DSA:1.10.10.770 319 433 2.6E-37 T 30-10-2018 CL1_1329 daa2f6fd9cd2a50a78cbb4c918642f4a 526 Gene3D G3DSA:3.40.50.620 4 270 2.2E-111 T 30-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CL1_1329 daa2f6fd9cd2a50a78cbb4c918642f4a 526 Gene3D G3DSA:1.10.10.350 434 526 3.5E-25 T 30-10-2018 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 CL1_1329 daa2f6fd9cd2a50a78cbb4c918642f4a 526 Pfam PF01921 tRNA synthetases class I (K) 3 362 3.3E-139 T 30-10-2018 IPR002904 Lysine-tRNA ligase GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 CL1_1081 32641bde98bd5dae5bcaee8520156d00 219 SMART SM00478 46 196 1.3E-30 T 30-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CL1_1081 32641bde98bd5dae5bcaee8520156d00 219 Pfam PF00633 Helix-hairpin-helix motif 106 135 6.2E-6 T 30-10-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 CL1_1081 32641bde98bd5dae5bcaee8520156d00 219 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 42 163 5.6E-10 T 30-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CL1_1081 32641bde98bd5dae5bcaee8520156d00 219 PIRSF PIRSF001435 8 218 1.2E-26 T 30-10-2018 CL1_1081 32641bde98bd5dae5bcaee8520156d00 219 Gene3D G3DSA:1.10.340.30 28 140 5.3E-68 T 30-10-2018 CL1_1081 32641bde98bd5dae5bcaee8520156d00 219 SMART SM00525 197 217 0.0042 T 30-10-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 CL1_1081 32641bde98bd5dae5bcaee8520156d00 219 Gene3D G3DSA:1.10.1670.10 19 214 5.3E-68 T 30-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 CL1_1081 32641bde98bd5dae5bcaee8520156d00 219 SUPERFAMILY SSF48150 12 215 1.22E-60 T 30-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CL1_1081 32641bde98bd5dae5bcaee8520156d00 219 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 198 214 - T 30-10-2018 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 CL1_0968 923cf98f8f779ba6d98178a93f19332b 599 Gene3D G3DSA:4.10.1080.10 68 185 4.3E-10 T 30-10-2018 IPR028974 TSP type-3 repeat GO:0005509 Reactome: R-HSA-186797 CL1_0968 923cf98f8f779ba6d98178a93f19332b 599 Pfam PF04473 Transglutaminase-like domain 278 432 2.1E-41 T 30-10-2018 IPR007562 Transglutaminase-like domain CL1_1513 d832460c116e6b6c849c92cd5bf15b23 248 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 70 242 1.0E-22 T 30-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 CL1_1513 d832460c116e6b6c849c92cd5bf15b23 248 SUPERFAMILY SSF161098 6 241 1.57E-46 T 30-10-2018 IPR035906 MetI-like superfamily CL1_1513 d832460c116e6b6c849c92cd5bf15b23 248 Gene3D G3DSA:1.10.3720.10 5 248 5.6E-64 T 30-10-2018 IPR035906 MetI-like superfamily CL1_0152 716fd4de319a4eec4128264bf5169917 267 Pfam PF10869 Protein of unknown function (DUF2666) 4 104 8.2E-13 T 30-10-2018 IPR022620 Protein of unknown function DUF2666 CL1_0152 716fd4de319a4eec4128264bf5169917 267 Pfam PF10869 Protein of unknown function (DUF2666) 138 266 8.1E-40 T 30-10-2018 IPR022620 Protein of unknown function DUF2666 CL1_0152 716fd4de319a4eec4128264bf5169917 267 ProDom PD033097 PH0063 MJ0596 ARCHAEAL PF2050 4 92 5.0E-24 T 30-10-2018 IPR022620 Protein of unknown function DUF2666 CL1_0152 716fd4de319a4eec4128264bf5169917 267 ProDom PD033097 PH0063 MJ0596 ARCHAEAL PF2050 138 266 4.0E-45 T 30-10-2018 IPR022620 Protein of unknown function DUF2666 CL1_0249 441ad5b613d4ed60dfb6bff094ea512b 169 Pfam PF01230 HIT domain 35 125 1.4E-14 T 30-10-2018 IPR001310 Histidine triad (HIT) protein CL1_0249 441ad5b613d4ed60dfb6bff094ea512b 169 SUPERFAMILY SSF54197 1 155 9.19E-47 T 30-10-2018 IPR036265 HIT-like superfamily CL1_0249 441ad5b613d4ed60dfb6bff094ea512b 169 Gene3D G3DSA:3.30.428.10 1 161 7.9E-59 T 30-10-2018 IPR036265 HIT-like superfamily CL1_0164 024f9b72a1644ee203af35db431584b0 337 SUPERFAMILY SSF55608 153 276 4.48E-12 T 30-10-2018 IPR027434 Homing endonuclease CL1_0164 024f9b72a1644ee203af35db431584b0 337 Pfam PF14528 LAGLIDADG-like domain 165 257 1.1E-11 T 30-10-2018 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 CL1_0164 024f9b72a1644ee203af35db431584b0 337 SUPERFAMILY SSF55608 70 146 6.17E-9 T 30-10-2018 IPR027434 Homing endonuclease CL1_0164 024f9b72a1644ee203af35db431584b0 337 Pfam PF14527 WhiA LAGLIDADG-like domain 75 123 4.7E-4 T 30-10-2018 IPR039518 WhiA, LAGLIDADG-like domain CL1_0164 024f9b72a1644ee203af35db431584b0 337 PRINTS PR00379 Intein signature 74 86 3.9E-6 T 30-10-2018 IPR006142 Intein GO:0016539 CL1_0164 024f9b72a1644ee203af35db431584b0 337 PRINTS PR00379 Intein signature 165 177 3.9E-6 T 30-10-2018 IPR006142 Intein GO:0016539 CL1_0164 024f9b72a1644ee203af35db431584b0 337 PRINTS PR00379 Intein signature 198 213 3.9E-6 T 30-10-2018 IPR006142 Intein GO:0016539 CL1_0164 024f9b72a1644ee203af35db431584b0 337 Gene3D G3DSA:3.10.28.10 71 235 4.0E-14 T 30-10-2018 IPR027434 Homing endonuclease CL1_0569 f6b49351a34dc6680c363ca1c4f6ba97 334 Hamap MF_00217 Mevalonate kinase [mvk]. 3 327 58.652 T 30-10-2018 IPR022937 Mevalonate kinase, archaeal GO:0004496 KEGG: 00900+2.7.1.36|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-922 CL1_0569 f6b49351a34dc6680c363ca1c4f6ba97 334 SUPERFAMILY SSF54211 3 180 2.2E-45 T 30-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CL1_0569 f6b49351a34dc6680c363ca1c4f6ba97 334 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 109 120 - T 30-10-2018 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 CL1_0569 f6b49351a34dc6680c363ca1c4f6ba97 334 TIGRFAM TIGR00549 mevalon_kin: mevalonate kinase 7 298 5.7E-86 T 30-10-2018 IPR006205 Mevalonate kinase GO:0004496|GO:0005524|GO:0005737|GO:0008299 KEGG: 00900+2.7.1.36|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-2426168 CL1_0569 f6b49351a34dc6680c363ca1c4f6ba97 334 Pfam PF00288 GHMP kinases N terminal domain 103 169 5.0E-16 T 30-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 CL1_0569 f6b49351a34dc6680c363ca1c4f6ba97 334 Gene3D G3DSA:3.30.230.10 1 182 9.2E-50 T 30-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CL1_0569 f6b49351a34dc6680c363ca1c4f6ba97 334 SUPERFAMILY SSF55060 183 329 2.88E-37 T 30-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily CL1_0569 f6b49351a34dc6680c363ca1c4f6ba97 334 PRINTS PR00959 Mevalonate kinase family signature 150 169 6.0E-29 T 30-10-2018 CL1_0569 f6b49351a34dc6680c363ca1c4f6ba97 334 PRINTS PR00959 Mevalonate kinase family signature 107 129 6.0E-29 T 30-10-2018 CL1_0569 f6b49351a34dc6680c363ca1c4f6ba97 334 PRINTS PR00959 Mevalonate kinase family signature 7 31 6.0E-29 T 30-10-2018 CL1_0569 f6b49351a34dc6680c363ca1c4f6ba97 334 PRINTS PR00959 Mevalonate kinase family signature 283 300 6.0E-29 T 30-10-2018 CL1_0569 f6b49351a34dc6680c363ca1c4f6ba97 334 Pfam PF08544 GHMP kinases C terminal 245 310 2.6E-13 T 30-10-2018 IPR013750 GHMP kinase, C-terminal domain CL1_0569 f6b49351a34dc6680c363ca1c4f6ba97 334 Gene3D G3DSA:3.30.70.890 187 319 3.7E-41 T 30-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily CL1_1760 f19c8f5e78f3a885610b1d8e6fcd0c79 81 Pfam PF04457 Protein of unknown function (DUF504) 26 77 1.5E-13 T 30-10-2018 IPR007547 Uncharacterised protein family UPF0248 CL1_1760 f19c8f5e78f3a885610b1d8e6fcd0c79 81 Hamap MF_01245 UPF0248 protein . 10 79 18.644 T 30-10-2018 IPR007547 Uncharacterised protein family UPF0248 CL1_0543 79d7b5e5a8adb6c4df469b1b2c45001e 511 SUPERFAMILY SSF161070 1 464 7.72E-103 T 30-10-2018 IPR037272 Sodium:neurotransmitter symporter superfamily GO:0005328 CL1_0543 79d7b5e5a8adb6c4df469b1b2c45001e 511 ProSitePatterns PS00610 Sodium:neurotransmitter symporter family signature 1. 12 26 - T 30-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 CL1_0543 79d7b5e5a8adb6c4df469b1b2c45001e 511 Pfam PF00209 Sodium:neurotransmitter symporter family 2 116 5.7E-19 T 30-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 CL1_0543 79d7b5e5a8adb6c4df469b1b2c45001e 511 Pfam PF00209 Sodium:neurotransmitter symporter family 147 443 3.3E-30 T 30-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 CL1_0543 79d7b5e5a8adb6c4df469b1b2c45001e 511 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 381 401 1.0E-8 T 30-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 CL1_0543 79d7b5e5a8adb6c4df469b1b2c45001e 511 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 25 44 1.0E-8 T 30-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 CL1_0543 79d7b5e5a8adb6c4df469b1b2c45001e 511 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 304 323 1.0E-8 T 30-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 CL1_1873 ea6af46d563f0fb99a9126175f4cfe47 242 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 108 188 2.7E-14 T 30-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 CL1_1873 ea6af46d563f0fb99a9126175f4cfe47 242 TIGRFAM TIGR02253 CTE7: HAD hydrolase, TIGR02253 family 1 220 4.7E-88 T 30-10-2018 IPR011950 HAD-superfamily hydrolase, subfamily IA, CTE7 GO:0016787 Reactome: R-HSA-4085001 CL1_1873 ea6af46d563f0fb99a9126175f4cfe47 242 Gene3D G3DSA:1.10.150.520 16 94 5.7E-87 T 30-10-2018 CL1_1873 ea6af46d563f0fb99a9126175f4cfe47 242 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 97 193 2.0E-11 T 30-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 CL1_1873 ea6af46d563f0fb99a9126175f4cfe47 242 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 137 153 4.7E-11 T 30-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 CL1_1873 ea6af46d563f0fb99a9126175f4cfe47 242 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 155 175 4.7E-11 T 30-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 CL1_1873 ea6af46d563f0fb99a9126175f4cfe47 242 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 2 13 4.7E-11 T 30-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 CL1_1873 ea6af46d563f0fb99a9126175f4cfe47 242 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 106 119 4.7E-11 T 30-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 CL1_1873 ea6af46d563f0fb99a9126175f4cfe47 242 Gene3D G3DSA:3.40.50.1000 4 219 5.7E-87 T 30-10-2018 IPR023214 HAD superfamily CL1_1873 ea6af46d563f0fb99a9126175f4cfe47 242 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 193 1.0E-31 T 30-10-2018 CL1_1873 ea6af46d563f0fb99a9126175f4cfe47 242 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 91 195 1.9E-13 T 30-10-2018 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 CL1_1873 ea6af46d563f0fb99a9126175f4cfe47 242 SUPERFAMILY SSF56784 1 225 2.23E-48 T 30-10-2018 IPR036412 HAD-like superfamily CL1_1373 1da3538f9fdcbe35af559fd48a097f66 439 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 268 275 4.9E-18 T 30-10-2018 CL1_1373 1da3538f9fdcbe35af559fd48a097f66 439 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 2 24 4.9E-18 T 30-10-2018 CL1_1373 1da3538f9fdcbe35af559fd48a097f66 439 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 145 170 4.9E-18 T 30-10-2018 CL1_1373 1da3538f9fdcbe35af559fd48a097f66 439 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 229 243 4.9E-18 T 30-10-2018 CL1_1373 1da3538f9fdcbe35af559fd48a097f66 439 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 324 423 7.2E-17 T 30-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CL1_1373 1da3538f9fdcbe35af559fd48a097f66 439 SUPERFAMILY SSF51905 1 191 7.2E-47 T 30-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily CL1_1373 1da3538f9fdcbe35af559fd48a097f66 439 Gene3D G3DSA:3.50.50.60 107 431 4.8E-147 T 30-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily CL1_1373 1da3538f9fdcbe35af559fd48a097f66 439 Gene3D G3DSA:3.50.50.60 2 331 4.8E-147 T 30-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily CL1_1373 1da3538f9fdcbe35af559fd48a097f66 439 SUPERFAMILY SSF55424 316 436 9.79E-27 T 30-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 CL1_1373 1da3538f9fdcbe35af559fd48a097f66 439 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 284 2.2E-69 T 30-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CL1_1373 1da3538f9fdcbe35af559fd48a097f66 439 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 228 244 2.1E-23 T 30-10-2018 CL1_1373 1da3538f9fdcbe35af559fd48a097f66 439 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 3 22 2.1E-23 T 30-10-2018 CL1_1373 1da3538f9fdcbe35af559fd48a097f66 439 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 98 116 2.1E-23 T 30-10-2018 CL1_1373 1da3538f9fdcbe35af559fd48a097f66 439 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 145 163 2.1E-23 T 30-10-2018 CL1_1373 1da3538f9fdcbe35af559fd48a097f66 439 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 253 275 2.1E-23 T 30-10-2018 CL1_1373 1da3538f9fdcbe35af559fd48a097f66 439 SUPERFAMILY SSF51905 143 307 7.42E-34 T 30-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily CL1_1458 56c8d6cd01433c295ad3e5baaa3d3545 65 Pfam PF01381 Helix-turn-helix 5 59 1.8E-20 T 30-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CL1_1458 56c8d6cd01433c295ad3e5baaa3d3545 65 SMART SM00530 4 59 8.6E-21 T 30-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CL1_1458 56c8d6cd01433c295ad3e5baaa3d3545 65 Gene3D G3DSA:1.10.260.40 1 65 1.5E-31 T 30-10-2018 CL1_1458 56c8d6cd01433c295ad3e5baaa3d3545 65 SUPERFAMILY SSF47413 2 64 5.09E-21 T 30-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 CL1_0667 c75e193cecbf5f4724026f28338a790a 269 Pfam PF03725 3' exoribonuclease family, domain 2 190 253 1.5E-11 T 30-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CL1_0667 c75e193cecbf5f4724026f28338a790a 269 Gene3D G3DSA:3.30.230.70 1 268 7.8E-86 T 30-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CL1_0667 c75e193cecbf5f4724026f28338a790a 269 Pfam PF01138 3' exoribonuclease family, domain 1 30 164 1.2E-28 T 30-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CL1_0667 c75e193cecbf5f4724026f28338a790a 269 SUPERFAMILY SSF55666 184 268 1.24E-22 T 30-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CL1_0667 c75e193cecbf5f4724026f28338a790a 269 Hamap MF_00622 Exosome complex component Rrp42 [rrp42]. 1 265 45.008 T 30-10-2018 IPR020869 Exosome complex component Rrp42, archaea GO:0000178|GO:0006401 CL1_0667 c75e193cecbf5f4724026f28338a790a 269 SUPERFAMILY SSF54211 10 212 2.53E-52 T 30-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CL1_1251 5fc0bf20ae0e04dbc55be5b18ce2315e 435 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 188 325 1.4E-14 T 30-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CL1_1251 5fc0bf20ae0e04dbc55be5b18ce2315e 435 Hamap MF_00900 GTPase HflX [hflX]. 17 390 43.698 T 30-10-2018 IPR016496 GTPase HflX GO:0005525 CL1_1251 5fc0bf20ae0e04dbc55be5b18ce2315e 435 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 209 227 2.5E-7 T 30-10-2018 IPR006073 GTP binding domain GO:0005525 CL1_1251 5fc0bf20ae0e04dbc55be5b18ce2315e 435 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 254 272 2.5E-7 T 30-10-2018 IPR006073 GTP binding domain GO:0005525 CL1_1251 5fc0bf20ae0e04dbc55be5b18ce2315e 435 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 188 208 2.5E-7 T 30-10-2018 IPR006073 GTP binding domain GO:0005525 CL1_1251 5fc0bf20ae0e04dbc55be5b18ce2315e 435 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 14 349 7.5E-95 T 30-10-2018 IPR016496 GTPase HflX GO:0005525 CL1_1251 5fc0bf20ae0e04dbc55be5b18ce2315e 435 PIRSF PIRSF006809 1 420 8.2E-124 T 30-10-2018 IPR016496 GTPase HflX GO:0005525 CL1_1251 5fc0bf20ae0e04dbc55be5b18ce2315e 435 SUPERFAMILY SSF52540 188 399 1.2E-39 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_1251 5fc0bf20ae0e04dbc55be5b18ce2315e 435 Pfam PF16360 GTP-binding GTPase Middle Region 103 180 9.8E-19 T 30-10-2018 IPR032305 GTP-binding protein, middle domain CL1_1251 5fc0bf20ae0e04dbc55be5b18ce2315e 435 Gene3D G3DSA:3.40.50.300 187 362 2.3E-42 T 30-10-2018 CL1_1251 5fc0bf20ae0e04dbc55be5b18ce2315e 435 Gene3D G3DSA:3.40.50.11060 11 129 1.2E-34 T 30-10-2018 CL1_1251 5fc0bf20ae0e04dbc55be5b18ce2315e 435 Pfam PF13167 GTP-binding GTPase N-terminal 17 100 1.8E-24 T 30-10-2018 IPR025121 GTPase HflX, N-terminal CL1_1251 5fc0bf20ae0e04dbc55be5b18ce2315e 435 Pfam PF01926 50S ribosome-binding GTPase 188 307 1.9E-21 T 30-10-2018 IPR006073 GTP binding domain GO:0005525 CL1_0924 f5c4d3e24dd8f9766422f4fb459c128a 276 Gene3D G3DSA:3.40.50.620 2 197 7.6E-28 T 30-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CL1_0924 f5c4d3e24dd8f9766422f4fb459c128a 276 PIRSF PIRSF036668 1 273 2.2E-127 T 30-10-2018 IPR012121 ATPase, PP-loop, MJ1599-related CL1_0924 f5c4d3e24dd8f9766422f4fb459c128a 276 Pfam PF06508 Queuosine biosynthesis protein QueC 54 134 3.7E-7 T 30-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 CL1_0924 f5c4d3e24dd8f9766422f4fb459c128a 276 SUPERFAMILY SSF52402 32 204 3.31E-30 T 30-10-2018 CL1_0727 64316335cd42c88c27992f644280e7f3 256 SMART SM00471 48 181 0.004 T 30-10-2018 IPR003607 HD/PDEase domain CL1_0727 64316335cd42c88c27992f644280e7f3 256 SUPERFAMILY SSF109604 50 170 3.14E-9 T 30-10-2018 CL1_0727 64316335cd42c88c27992f644280e7f3 256 Gene3D G3DSA:1.10.3210.10 22 202 6.7E-8 T 30-10-2018 CL1_0299 d807beceb482a84dc718b2f823041e25 128 Gene3D G3DSA:1.20.120.580 49 128 3.5E-5 T 30-10-2018 IPR037038 Bsu32300-like superfamily CL1_0299 d807beceb482a84dc718b2f823041e25 128 Pfam PF01934 Protein of unknown function DUF86 8 123 2.5E-9 T 30-10-2018 IPR008201 Protein of unknown function DUF86 CL1_0858 d66e6002b21517d41fe8277ccf53e60e 374 Gene3D G3DSA:3.40.50.2000 194 359 1.2E-36 T 30-10-2018 CL1_0858 d66e6002b21517d41fe8277ccf53e60e 374 Pfam PF13579 Glycosyl transferase 4-like domain 16 179 7.9E-9 T 30-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 CL1_0858 d66e6002b21517d41fe8277ccf53e60e 374 SUPERFAMILY SSF53756 2 369 6.8E-65 T 30-10-2018 CL1_0858 d66e6002b21517d41fe8277ccf53e60e 374 Gene3D G3DSA:3.40.50.2000 1 193 1.4E-18 T 30-10-2018 CL1_0858 d66e6002b21517d41fe8277ccf53e60e 374 Pfam PF00534 Glycosyl transferases group 1 182 343 2.4E-32 T 30-10-2018 IPR001296 Glycosyl transferase, family 1 CL1_0893 1db0be839f426b85b7cca174721bac36 271 SUPERFAMILY SSF56281 3 252 3.79E-36 T 30-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like CL1_0893 1db0be839f426b85b7cca174721bac36 271 Gene3D G3DSA:3.60.15.10 1 253 1.2E-28 T 30-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like CL1_0893 1db0be839f426b85b7cca174721bac36 271 Pfam PF12706 Beta-lactamase superfamily domain 32 220 4.9E-26 T 30-10-2018 IPR001279 Metallo-beta-lactamase CL1_1970 822cbb2645e612b1e4d5412c6621b0a4 286 SUPERFAMILY SSF103481 184 274 1.57E-8 T 30-10-2018 CL1_1970 822cbb2645e612b1e4d5412c6621b0a4 286 SUPERFAMILY SSF103481 43 145 5.89E-12 T 30-10-2018 CL1_1970 822cbb2645e612b1e4d5412c6621b0a4 286 Pfam PF00892 EamA-like transporter family 9 142 2.4E-18 T 30-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CL1_1970 822cbb2645e612b1e4d5412c6621b0a4 286 Pfam PF00892 EamA-like transporter family 151 274 1.6E-12 T 30-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CL1_0754 dfeb7226b89268183bf3870a81f2bfca 354 SUPERFAMILY SSF51306 34 102 4.97E-12 T 30-10-2018 IPR036286 LexA/Signal peptidase-like superfamily CL1_0754 dfeb7226b89268183bf3870a81f2bfca 354 PRINTS PR00728 Eukaryotic signal peptidase (S26B) family signature 86 97 1.3E-6 T 30-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 CL1_0754 dfeb7226b89268183bf3870a81f2bfca 354 PRINTS PR00728 Eukaryotic signal peptidase (S26B) family signature 35 50 1.3E-6 T 30-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 CL1_0754 dfeb7226b89268183bf3870a81f2bfca 354 TIGRFAM TIGR02228 sigpep_I_arch: signal peptidase I 7 111 2.8E-16 T 30-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 CL1_0754 dfeb7226b89268183bf3870a81f2bfca 354 Gene3D G3DSA:2.10.109.10 36 132 1.3E-9 T 30-10-2018 CL1_0754 dfeb7226b89268183bf3870a81f2bfca 354 Pfam PF00717 Peptidase S24-like 36 94 7.2E-11 T 30-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CL1_0344 2eddb55c8d6c12e01472cf60a7596483 247 SUPERFAMILY SSF52540 3 244 2.82E-47 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_0344 2eddb55c8d6c12e01472cf60a7596483 247 Gene3D G3DSA:3.40.50.300 2 241 9.3E-48 T 30-10-2018 CL1_0344 2eddb55c8d6c12e01472cf60a7596483 247 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 3 221 1.4E-19 T 30-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain CL1_1516 6e2c3da608edfbb12b944a0d89713a03 312 SUPERFAMILY SSF52129 80 245 4.08E-11 T 30-10-2018 IPR029030 Caspase-like domain superfamily CL1_1516 6e2c3da608edfbb12b944a0d89713a03 312 Pfam PF00656 Caspase domain 83 228 8.4E-22 T 30-10-2018 CL1_1516 6e2c3da608edfbb12b944a0d89713a03 312 Gene3D G3DSA:3.40.50.1460 81 301 2.7E-40 T 30-10-2018 CL1_0054 8e918f04de6ed42d0978cf482260cd5e 381 Pfam PF05559 Protein of unknown function (DUF763) 4 335 4.3E-121 T 30-10-2018 IPR008482 Protein of unknown function DUF763 CL1_1157 d4576807fedb5a792dd65460e4ee3953 535 Gene3D G3DSA:3.60.21.10 309 527 1.7E-15 T 30-10-2018 IPR029052 Metallo-dependent phosphatase-like CL1_1157 d4576807fedb5a792dd65460e4ee3953 535 Pfam PF00149 Calcineurin-like phosphoesterase 307 483 1.3E-8 T 30-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CL1_1157 d4576807fedb5a792dd65460e4ee3953 535 SUPERFAMILY SSF56300 310 515 7.41E-31 T 30-10-2018 CL1_1912 3dbbffbea0ca29c4c656ef87ebfe7337 264 Gene3D G3DSA:3.40.50.300 1 241 4.9E-63 T 30-10-2018 CL1_1912 3dbbffbea0ca29c4c656ef87ebfe7337 264 SUPERFAMILY SSF52540 3 228 9.52E-59 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_1912 3dbbffbea0ca29c4c656ef87ebfe7337 264 Pfam PF00005 ABC transporter 20 165 2.7E-27 T 30-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CL1_1912 3dbbffbea0ca29c4c656ef87ebfe7337 264 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 30-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CL1_1912 3dbbffbea0ca29c4c656ef87ebfe7337 264 SMART SM00382 28 215 2.2E-15 T 30-10-2018 IPR003593 AAA+ ATPase domain CL1_0211 529f16c93ccd51eaf6b6b38dffd7880e 105 Pfam PF13192 Thioredoxin domain 22 96 2.9E-10 T 30-10-2018 IPR012336 Thioredoxin-like fold CL1_0211 529f16c93ccd51eaf6b6b38dffd7880e 105 Gene3D G3DSA:3.40.30.10 11 98 1.7E-15 T 30-10-2018 CL1_0211 529f16c93ccd51eaf6b6b38dffd7880e 105 SUPERFAMILY SSF52833 16 92 2.08E-16 T 30-10-2018 IPR036249 Thioredoxin-like superfamily CL1_1194 d8bcff2c84054e54a19e6b197f7f39e3 189 SUPERFAMILY SSF52141 3 186 5.89E-62 T 30-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CL1_1194 d8bcff2c84054e54a19e6b197f7f39e3 189 SMART SM00987 25 185 1.6E-38 T 30-10-2018 CL1_1194 d8bcff2c84054e54a19e6b197f7f39e3 189 SMART SM00986 25 185 1.6E-38 T 30-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CL1_1194 d8bcff2c84054e54a19e6b197f7f39e3 189 Gene3D G3DSA:3.40.470.10 1 187 5.0E-71 T 30-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CL1_1194 d8bcff2c84054e54a19e6b197f7f39e3 189 TIGRFAM TIGR00758 UDG_fam4: uracil-DNA glycosylase, family 4 11 185 1.9E-76 T 30-10-2018 IPR005273 Uracil-DNA glycosylase family 4 CL1_1194 d8bcff2c84054e54a19e6b197f7f39e3 189 Pfam PF03167 Uracil DNA glycosylase superfamily 25 178 1.7E-47 T 30-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CL1_1995 434e01cf4d24346efe68c93e71834b88 315 PIRSF PIRSF006004 1 306 2.9E-39 T 30-10-2018 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 CL1_1995 434e01cf4d24346efe68c93e71834b88 315 Pfam PF04055 Radical SAM superfamily 46 202 5.7E-9 T 30-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CL1_1995 434e01cf4d24346efe68c93e71834b88 315 Gene3D G3DSA:3.20.20.70 10 274 1.7E-26 T 30-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CL1_1995 434e01cf4d24346efe68c93e71834b88 315 SUPERFAMILY SSF102114 42 210 1.96E-11 T 30-10-2018 CL1_0013 c530038b6d9570b41bf4cc792349529d 90 Gene3D G3DSA:3.30.70.20 1 90 4.6E-17 T 30-10-2018 CL1_0013 c530038b6d9570b41bf4cc792349529d 90 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 34 45 - T 30-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CL1_0013 c530038b6d9570b41bf4cc792349529d 90 Pfam PF12838 4Fe-4S dicluster domain 34 82 3.2E-11 T 30-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CL1_0013 c530038b6d9570b41bf4cc792349529d 90 SUPERFAMILY SSF54862 25 88 3.35E-15 T 30-10-2018 CL1_0013 c530038b6d9570b41bf4cc792349529d 90 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 71 82 - T 30-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CL1_0098 3fde75e86cb442c7931431a351e3e36d 378 TIGRFAM TIGR00308 TRM1: N2,N2-dimethylguanosine tRNA methyltransferase 6 377 4.0E-97 T 30-10-2018 IPR002905 tRNA methyltransferase, Trm1 GO:0003723|GO:0004809|GO:0008033 MetaCyc: PWY-6829 CL1_0098 3fde75e86cb442c7931431a351e3e36d 378 Hamap MF_00290 tRNA (guanine(26)-N(2))-dimethyltransferase [trm1]. 4 376 43.369 T 30-10-2018 IPR022923 tRNA (guanine(26)-N(2))-dimethyltransferase, archaeal and bacterial GO:0004809 MetaCyc: PWY-6829 CL1_0098 3fde75e86cb442c7931431a351e3e36d 378 SUPERFAMILY SSF53335 3 375 3.0E-107 T 30-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CL1_0098 3fde75e86cb442c7931431a351e3e36d 378 Pfam PF02005 N2,N2-dimethylguanosine tRNA methyltransferase 9 374 3.8E-114 T 30-10-2018 IPR002905 tRNA methyltransferase, Trm1 GO:0003723|GO:0004809|GO:0008033 MetaCyc: PWY-6829 CL1_0098 3fde75e86cb442c7931431a351e3e36d 378 Gene3D G3DSA:3.30.56.70 318 377 5.1E-23 T 30-10-2018 CL1_0098 3fde75e86cb442c7931431a351e3e36d 378 Gene3D G3DSA:3.40.50.150 1 317 1.3E-102 T 30-10-2018 CL1_1826 1ae0ec4cbcf4685dd7acc60a52a3a412 178 Gene3D G3DSA:3.30.230.40 76 176 1.1E-32 T 30-10-2018 IPR038494 Imidazole glycerol phosphate dehydratase domain superfamily KEGG: 00340+4.2.1.19 CL1_1826 1ae0ec4cbcf4685dd7acc60a52a3a412 178 SUPERFAMILY SSF54211 2 73 2.78E-15 T 30-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CL1_1826 1ae0ec4cbcf4685dd7acc60a52a3a412 178 SUPERFAMILY SSF54211 75 164 1.14E-24 T 30-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CL1_1826 1ae0ec4cbcf4685dd7acc60a52a3a412 178 Gene3D G3DSA:3.30.230.40 1 75 2.1E-19 T 30-10-2018 IPR038494 Imidazole glycerol phosphate dehydratase domain superfamily KEGG: 00340+4.2.1.19 CL1_1826 1ae0ec4cbcf4685dd7acc60a52a3a412 178 ProSitePatterns PS00955 Imidazoleglycerol-phosphate dehydratase signature 2. 141 153 - T 30-10-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 CL1_1826 1ae0ec4cbcf4685dd7acc60a52a3a412 178 Pfam PF00475 Imidazoleglycerol-phosphate dehydratase 22 159 9.6E-38 T 30-10-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 CL1_0202 4348089b5584d6619d75b6139d3e5f90 228 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 58 69 - T 30-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CL1_0202 4348089b5584d6619d75b6139d3e5f90 228 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 97 108 - T 30-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CL1_0202 4348089b5584d6619d75b6139d3e5f90 228 Pfam PF12838 4Fe-4S dicluster domain 57 111 1.4E-11 T 30-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CL1_0202 4348089b5584d6619d75b6139d3e5f90 228 Gene3D G3DSA:3.30.70.3270 36 167 3.6E-24 T 30-10-2018 CL1_0202 4348089b5584d6619d75b6139d3e5f90 228 SUPERFAMILY SSF54862 20 115 4.81E-22 T 30-10-2018 CL1_1759 38da4a3ebafb607e1d898150bd1dba3e 323 Pfam PF05763 Protein of unknown function (DUF835) 184 319 4.1E-28 T 30-10-2018 IPR008553 Domain of unknown function DUF835 CL1_1759 38da4a3ebafb607e1d898150bd1dba3e 323 Gene3D G3DSA:1.20.1260.10 15 163 2.1E-34 T 30-10-2018 IPR012347 Ferritin-like CL1_1759 38da4a3ebafb607e1d898150bd1dba3e 323 SUPERFAMILY SSF47240 20 164 5.78E-30 T 30-10-2018 IPR009078 Ferritin-like superfamily CL1_1759 38da4a3ebafb607e1d898150bd1dba3e 323 Pfam PF02915 Rubrerythrin 25 159 6.0E-22 T 30-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 CL1_0475 c27200dd08a16d2eec05fc9554c89775 314 SMART SM00849 19 207 1.4E-4 T 30-10-2018 IPR001279 Metallo-beta-lactamase CL1_0475 c27200dd08a16d2eec05fc9554c89775 314 Hamap MF_01818 Ribonuclease BN [rbn]. 2 299 34.153 T 30-10-2018 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 CL1_0475 c27200dd08a16d2eec05fc9554c89775 314 Pfam PF12706 Beta-lactamase superfamily domain 197 263 5.1E-8 T 30-10-2018 IPR001279 Metallo-beta-lactamase CL1_0475 c27200dd08a16d2eec05fc9554c89775 314 Pfam PF12706 Beta-lactamase superfamily domain 32 152 8.6E-11 T 30-10-2018 IPR001279 Metallo-beta-lactamase CL1_0475 c27200dd08a16d2eec05fc9554c89775 314 SUPERFAMILY SSF56281 3 298 9.32E-74 T 30-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like CL1_0475 c27200dd08a16d2eec05fc9554c89775 314 TIGRFAM TIGR02651 RNase_Z: ribonuclease Z 3 293 1.7E-96 T 30-10-2018 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 CL1_0475 c27200dd08a16d2eec05fc9554c89775 314 Gene3D G3DSA:3.60.15.10 1 299 4.5E-82 T 30-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like CL1_0354 0d60194c20dd813a217ff72422b4def2 245 TIGRFAM TIGR01482 SPP-subfamily: sucrose-phosphate phosphatase subfamily 5 232 2.4E-71 T 30-10-2018 CL1_0354 0d60194c20dd813a217ff72422b4def2 245 SUPERFAMILY SSF56784 1 228 3.23E-39 T 30-10-2018 IPR036412 HAD-like superfamily CL1_0354 0d60194c20dd813a217ff72422b4def2 245 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 5 196 2.3E-15 T 30-10-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 CL1_0354 0d60194c20dd813a217ff72422b4def2 245 TIGRFAM TIGR01487 Pglycolate_arch: phosphoglycolate phosphatase, TA0175-type 2 222 5.0E-75 T 30-10-2018 CL1_0354 0d60194c20dd813a217ff72422b4def2 245 Gene3D G3DSA:3.40.50.1000 3 223 4.0E-72 T 30-10-2018 IPR023214 HAD superfamily CL1_0354 0d60194c20dd813a217ff72422b4def2 245 Hamap MF_01419 Phosphoglycolate phosphatase. 2 229 32.476 T 30-10-2018 IPR006382 Phosphoglycolate phosphatase GO:0000287|GO:0008967|GO:0016311 KEGG: 00630+3.1.3.18|MetaCyc: PWY-181 CL1_0354 0d60194c20dd813a217ff72422b4def2 245 Gene3D G3DSA:3.90.1070.10 86 153 4.0E-72 T 30-10-2018 CL1_0354 0d60194c20dd813a217ff72422b4def2 245 Pfam PF08282 haloacid dehalogenase-like hydrolase 139 224 7.5E-18 T 30-10-2018 CL1_0354 0d60194c20dd813a217ff72422b4def2 245 Pfam PF08282 haloacid dehalogenase-like hydrolase 5 79 3.8E-6 T 30-10-2018 CL1_0288 12db2678f3517887d7a575a5a150d865 359 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 191 209 2.3E-13 T 30-10-2018 IPR006073 GTP binding domain GO:0005525 CL1_0288 12db2678f3517887d7a575a5a150d865 359 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 218 233 2.3E-13 T 30-10-2018 IPR006073 GTP binding domain GO:0005525 CL1_0288 12db2678f3517887d7a575a5a150d865 359 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 170 190 2.3E-13 T 30-10-2018 IPR006073 GTP binding domain GO:0005525 CL1_0288 12db2678f3517887d7a575a5a150d865 359 Gene3D G3DSA:1.20.120.1190 1 161 8.5E-57 T 30-10-2018 CL1_0288 12db2678f3517887d7a575a5a150d865 359 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 169 328 7.5E-17 T 30-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CL1_0288 12db2678f3517887d7a575a5a150d865 359 Gene3D G3DSA:3.40.50.300 162 357 3.5E-58 T 30-10-2018 CL1_0288 12db2678f3517887d7a575a5a150d865 359 Pfam PF06858 Nucleolar GTP-binding protein 1 (NOG1) 234 291 3.0E-24 T 30-10-2018 IPR010674 Nucleolar GTP-binding protein 1, Rossman-fold domain GO:0005525 CL1_0288 12db2678f3517887d7a575a5a150d865 359 SUPERFAMILY SSF52540 168 352 3.16E-43 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_1223 02683d568b64c854acdaad333d273105 213 Pfam PF04252 Predicted SAM-dependent RNA methyltransferase 7 190 5.2E-42 T 30-10-2018 IPR007364 RNA methyltransferase TK0422/Sfm1 GO:0008168 CL1_1342 c3c2f1a079cf8179bca59f17fa9b19e8 440 Gene3D G3DSA:3.90.550.10 206 436 9.1E-46 T 30-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases CL1_1342 c3c2f1a079cf8179bca59f17fa9b19e8 440 Pfam PF00535 Glycosyl transferase family 2 221 341 1.5E-22 T 30-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CL1_1342 c3c2f1a079cf8179bca59f17fa9b19e8 440 Gene3D G3DSA:3.40.50.1000 1 192 1.5E-31 T 30-10-2018 IPR023214 HAD superfamily CL1_1342 c3c2f1a079cf8179bca59f17fa9b19e8 440 SUPERFAMILY SSF53448 217 430 5.79E-33 T 30-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases CL1_1342 c3c2f1a079cf8179bca59f17fa9b19e8 440 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 181 1.6E-20 T 30-10-2018 CL1_1342 c3c2f1a079cf8179bca59f17fa9b19e8 440 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 145 165 1.0E-7 T 30-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 CL1_1342 c3c2f1a079cf8179bca59f17fa9b19e8 440 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 94 107 1.0E-7 T 30-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 CL1_1342 c3c2f1a079cf8179bca59f17fa9b19e8 440 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 172 185 1.0E-7 T 30-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 CL1_1342 c3c2f1a079cf8179bca59f17fa9b19e8 440 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 3 14 1.0E-7 T 30-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 CL1_1342 c3c2f1a079cf8179bca59f17fa9b19e8 440 SUPERFAMILY SSF56784 2 212 3.6E-39 T 30-10-2018 IPR036412 HAD-like superfamily CL1_0526 6df64762fc6c334bef14869d0014f080 233 SUPERFAMILY SSF52540 15 191 9.85E-16 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_0526 6df64762fc6c334bef14869d0014f080 233 Gene3D G3DSA:3.40.50.300 11 233 5.2E-32 T 30-10-2018 CL1_1402 d63df808492591c6e7142a0a1599a51b 226 Gene3D G3DSA:3.40.50.150 51 226 2.2E-73 T 30-10-2018 CL1_1402 d63df808492591c6e7142a0a1599a51b 226 Hamap MF_00351 Fibrillarin-like rRNA/tRNA 2'-O-methyltransferase [flpA]. 16 226 44.017 T 30-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 CL1_1402 d63df808492591c6e7142a0a1599a51b 226 SMART SM01206 3 226 1.3E-144 T 30-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 CL1_1402 d63df808492591c6e7142a0a1599a51b 226 ProSitePatterns PS00566 Fibrillarin signature. 98 112 - T 30-10-2018 IPR020813 Fibrillarin, conserved site GO:0003723|GO:0006364|GO:0008168 CL1_1402 d63df808492591c6e7142a0a1599a51b 226 Pfam PF01269 Fibrillarin 4 224 6.3E-100 T 30-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 CL1_1402 d63df808492591c6e7142a0a1599a51b 226 PIRSF PIRSF006540 1 226 6.8E-100 T 30-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 CL1_1402 d63df808492591c6e7142a0a1599a51b 226 Gene3D G3DSA:3.30.200.20 1 50 2.1E-25 T 30-10-2018 CL1_1402 d63df808492591c6e7142a0a1599a51b 226 PRINTS PR00052 Fibrillarin signature 204 225 7.2E-79 T 30-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 CL1_1402 d63df808492591c6e7142a0a1599a51b 226 PRINTS PR00052 Fibrillarin signature 73 94 7.2E-79 T 30-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 CL1_1402 d63df808492591c6e7142a0a1599a51b 226 PRINTS PR00052 Fibrillarin signature 123 152 7.2E-79 T 30-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 CL1_1402 d63df808492591c6e7142a0a1599a51b 226 PRINTS PR00052 Fibrillarin signature 153 182 7.2E-79 T 30-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 CL1_1402 d63df808492591c6e7142a0a1599a51b 226 PRINTS PR00052 Fibrillarin signature 46 65 7.2E-79 T 30-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 CL1_1402 d63df808492591c6e7142a0a1599a51b 226 PRINTS PR00052 Fibrillarin signature 23 42 7.2E-79 T 30-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 CL1_1402 d63df808492591c6e7142a0a1599a51b 226 PRINTS PR00052 Fibrillarin signature 98 115 7.2E-79 T 30-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 CL1_1402 d63df808492591c6e7142a0a1599a51b 226 SUPERFAMILY SSF53335 3 225 5.31E-60 T 30-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CL1_0402 254ef2aba3407b08d0f4e6eb2aefaec4 339 SUPERFAMILY SSF160369 5 141 8.5E-25 T 30-10-2018 CL1_0402 254ef2aba3407b08d0f4e6eb2aefaec4 339 Hamap MF_00280 50S ribosomal protein L10 [rpl10]. 1 283 36.098 T 30-10-2018 IPR022909 50S ribosomal protein L10, archaea CL1_0402 254ef2aba3407b08d0f4e6eb2aefaec4 339 Gene3D G3DSA:3.90.105.20 107 186 6.2E-75 T 30-10-2018 CL1_0402 254ef2aba3407b08d0f4e6eb2aefaec4 339 Pfam PF00466 Ribosomal protein L10 5 105 1.1E-21 T 30-10-2018 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 CL1_0402 254ef2aba3407b08d0f4e6eb2aefaec4 339 Gene3D G3DSA:3.30.70.1730 15 211 6.2E-75 T 30-10-2018 CL1_0237 b562b00357b1af9fbc49a9142acb2038 190 Pfam PF01588 Putative tRNA binding domain 87 173 1.2E-18 T 30-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 CL1_0237 b562b00357b1af9fbc49a9142acb2038 190 Gene3D G3DSA:1.20.1440.150 1 73 8.1E-30 T 30-10-2018 CL1_0237 b562b00357b1af9fbc49a9142acb2038 190 SUPERFAMILY SSF50249 83 173 1.13E-16 T 30-10-2018 IPR012340 Nucleic acid-binding, OB-fold CL1_0237 b562b00357b1af9fbc49a9142acb2038 190 Gene3D G3DSA:2.40.50.140 74 190 2.4E-35 T 30-10-2018 CL1_0997 399599976b635494969227dc2ec7a340 294 Gene3D G3DSA:3.90.550.10 1 237 6.9E-65 T 30-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases CL1_0997 399599976b635494969227dc2ec7a340 294 Pfam PF00535 Glycosyl transferase family 2 6 169 1.5E-28 T 30-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CL1_0997 399599976b635494969227dc2ec7a340 294 SUPERFAMILY SSF53448 3 213 1.31E-59 T 30-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases CL1_0799 071929a17cb46f98716545d9c2072cd4 302 Gene3D G3DSA:3.40.50.10800 8 282 3.9E-123 T 30-10-2018 CL1_0799 071929a17cb46f98716545d9c2072cd4 302 Gene3D G3DSA:3.40.50.10800 173 257 3.9E-123 T 30-10-2018 CL1_0799 071929a17cb46f98716545d9c2072cd4 302 SUPERFAMILY SSF142754 6 301 4.97E-114 T 30-10-2018 IPR036094 Quinolinate synthetase A superfamily GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 CL1_0799 071929a17cb46f98716545d9c2072cd4 302 Pfam PF02445 Quinolinate synthetase A protein 9 300 2.1E-111 T 30-10-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 CL1_0799 071929a17cb46f98716545d9c2072cd4 302 Gene3D G3DSA:3.40.50.10800 88 300 3.9E-123 T 30-10-2018 CL1_0799 071929a17cb46f98716545d9c2072cd4 302 Hamap MF_00568 Quinolinate synthase A [nadA]. 4 301 44.931 T 30-10-2018 IPR023066 Quinolinate synthase A, type 2 GO:0016765 MetaCyc: PWY-5316|MetaCyc: PWY-7342 CL1_0799 071929a17cb46f98716545d9c2072cd4 302 TIGRFAM TIGR00550 nadA: quinolinate synthetase complex, A subunit 3 302 3.8E-114 T 30-10-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 CL1_0644 ed6fbde5eb444fd1699b99b137393896 415 ProSitePatterns PS00508 Nickel-dependent hydrogenases large subunit signature 2. 402 411 - T 30-10-2018 IPR018194 Nickel-dependent hydrogenase, large subunit, nickel binding site GO:0008901|GO:0016151|GO:0055114 CL1_0644 ed6fbde5eb444fd1699b99b137393896 415 SUPERFAMILY SSF56762 4 411 1.44E-92 T 30-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CL1_0644 ed6fbde5eb444fd1699b99b137393896 415 Pfam PF00374 Nickel-dependent hydrogenase 39 124 1.9E-14 T 30-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 CL1_0644 ed6fbde5eb444fd1699b99b137393896 415 Pfam PF00374 Nickel-dependent hydrogenase 224 411 1.1E-15 T 30-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 CL1_0644 ed6fbde5eb444fd1699b99b137393896 415 Gene3D G3DSA:1.10.645.10 1 411 1.0E-97 T 30-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CL1_0389 521140336e33ec36553c88250ed0db5d 716 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 635 672 1.3E-13 T 30-10-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 CL1_0389 521140336e33ec36553c88250ed0db5d 716 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 196 214 3.1E-25 T 30-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CL1_0389 521140336e33ec36553c88250ed0db5d 716 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 313 322 3.1E-25 T 30-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CL1_0389 521140336e33ec36553c88250ed0db5d 716 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 392 408 3.1E-25 T 30-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CL1_0389 521140336e33ec36553c88250ed0db5d 716 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 103 116 3.1E-25 T 30-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CL1_0389 521140336e33ec36553c88250ed0db5d 716 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 491 505 3.1E-25 T 30-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CL1_0389 521140336e33ec36553c88250ed0db5d 716 Pfam PF01131 DNA topoisomerase 156 564 2.5E-134 T 30-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CL1_0389 521140336e33ec36553c88250ed0db5d 716 SUPERFAMILY SSF57783 636 674 2.38E-5 T 30-10-2018 CL1_0389 521140336e33ec36553c88250ed0db5d 716 SMART SM00436 131 226 7.6E-43 T 30-10-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 CL1_0389 521140336e33ec36553c88250ed0db5d 716 SUPERFAMILY SSF56712 2 647 6.93E-163 T 30-10-2018 IPR023405 DNA topoisomerase, type IA, core domain CL1_0389 521140336e33ec36553c88250ed0db5d 716 Gene3D G3DSA:1.10.290.10 279 406 2.5E-124 T 30-10-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 CL1_0389 521140336e33ec36553c88250ed0db5d 716 SMART SM00437 271 527 2.5E-102 T 30-10-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 CL1_0389 521140336e33ec36553c88250ed0db5d 716 TIGRFAM TIGR01057 topA_arch: DNA topoisomerase I 6 665 1.0E-285 T 30-10-2018 IPR005739 DNA topoisomerase I, archeal-type GO:0003677|GO:0003916|GO:0006265 CL1_0389 521140336e33ec36553c88250ed0db5d 716 Gene3D G3DSA:1.10.460.10 163 574 2.5E-124 T 30-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 CL1_0389 521140336e33ec36553c88250ed0db5d 716 SMART SM00493 2 129 6.0E-19 T 30-10-2018 IPR006171 TOPRIM domain CL1_0389 521140336e33ec36553c88250ed0db5d 716 Hamap MF_00952 DNA topoisomerase 1 [topA]. 2 704 50.936 T 30-10-2018 IPR028612 DNA topoisomerase I, type IA GO:0003677|GO:0003916|GO:0006265 CL1_0389 521140336e33ec36553c88250ed0db5d 716 Gene3D G3DSA:2.70.20.10 220 475 2.5E-124 T 30-10-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 CL1_0389 521140336e33ec36553c88250ed0db5d 716 Pfam PF01751 Toprim domain 3 139 7.4E-18 T 30-10-2018 IPR006171 TOPRIM domain CL1_0389 521140336e33ec36553c88250ed0db5d 716 Gene3D G3DSA:3.40.50.140 1 154 6.5E-30 T 30-10-2018 CL1_0573 8dd7680ba5b7327ab7c9550499b97880 267 Gene3D G3DSA:3.40.50.1580 1 266 3.0E-99 T 30-10-2018 CL1_0573 8dd7680ba5b7327ab7c9550499b97880 267 TIGRFAM TIGR01694 MTAP: methylthioadenosine phosphorylase 4 247 4.7E-95 T 30-10-2018 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112|Reactome: R-HSA-8950505 CL1_0573 8dd7680ba5b7327ab7c9550499b97880 267 SUPERFAMILY SSF53167 1 264 9.56E-95 T 30-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 CL1_0573 8dd7680ba5b7327ab7c9550499b97880 267 Pfam PF01048 Phosphorylase superfamily 3 246 1.5E-53 T 30-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CL1_0573 8dd7680ba5b7327ab7c9550499b97880 267 ProSitePatterns PS01240 Purine and other phosphorylases family 2 signature. 48 88 - T 30-10-2018 IPR018099 Purine phosphorylase, family 2, conserved site GO:0016763 CL1_0573 8dd7680ba5b7327ab7c9550499b97880 267 Hamap MF_01963 S-methyl-5'-thioadenosine phosphorylase [mtnP]. 2 266 43.497 T 30-10-2018 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112|Reactome: R-HSA-8950505 CL1_1845 9c075ec8d51945def7b214405251931c 428 Gene3D G3DSA:3.40.30.10 23 172 8.7E-12 T 30-10-2018 CL1_1845 9c075ec8d51945def7b214405251931c 428 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 204 410 1.0E-8 T 30-10-2018 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 CL1_1845 9c075ec8d51945def7b214405251931c 428 SUPERFAMILY SSF52833 29 172 1.7E-11 T 30-10-2018 IPR036249 Thioredoxin-like superfamily CL1_0598 5f2629674da80eb9291fc6e8dc2b1347 235 Gene3D G3DSA:3.40.50.720 1 233 6.0E-53 T 30-10-2018 CL1_0598 5f2629674da80eb9291fc6e8dc2b1347 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 182 5.2E-15 T 30-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CL1_0598 5f2629674da80eb9291fc6e8dc2b1347 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 5.2E-15 T 30-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CL1_0598 5f2629674da80eb9291fc6e8dc2b1347 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 73 84 5.2E-15 T 30-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CL1_0598 5f2629674da80eb9291fc6e8dc2b1347 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 144 163 5.2E-15 T 30-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CL1_0598 5f2629674da80eb9291fc6e8dc2b1347 235 Pfam PF00106 short chain dehydrogenase 2 183 5.9E-38 T 30-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CL1_0598 5f2629674da80eb9291fc6e8dc2b1347 235 SUPERFAMILY SSF51735 1 210 8.33E-51 T 30-10-2018 IPR036291 NAD(P)-binding domain superfamily CL1_1806 8286b731c1aee484008b62176cf26b1d 281 Gene3D G3DSA:3.20.20.70 2 279 3.1E-84 T 30-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CL1_1806 8286b731c1aee484008b62176cf26b1d 281 SMART SM01133 23 251 2.2E-44 T 30-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 CL1_1806 8286b731c1aee484008b62176cf26b1d 281 SUPERFAMILY SSF51569 8 266 2.16E-69 T 30-10-2018 CL1_1806 8286b731c1aee484008b62176cf26b1d 281 PIRSF PIRSF038992 4 280 7.1E-91 T 30-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 CL1_1806 8286b731c1aee484008b62176cf26b1d 281 Pfam PF01791 DeoC/LacD family aldolase 24 251 9.4E-34 T 30-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 CL1_0002 414acbe818da7ffd2fa730d82b508d4f 115 PIRSF PIRSF006113 1 115 1.2E-35 T 30-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 CL1_0002 414acbe818da7ffd2fa730d82b508d4f 115 Gene3D G3DSA:3.30.479.10 1 115 1.2E-39 T 30-10-2018 IPR038418 6-pyruvoyl tetrahydropterin synthase/QueD superfamily Reactome: R-HSA-1474151 CL1_0002 414acbe818da7ffd2fa730d82b508d4f 115 SUPERFAMILY SSF55620 1 114 2.17E-32 T 30-10-2018 CL1_0002 414acbe818da7ffd2fa730d82b508d4f 115 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 5 113 1.9E-28 T 30-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 CL1_1805 7ce8c8b7b58acb13270426e78859c615 593 Pfam PF00364 Biotin-requiring enzyme 527 592 8.9E-24 T 30-10-2018 IPR000089 Biotin/lipoyl attachment CL1_1805 7ce8c8b7b58acb13270426e78859c615 593 SUPERFAMILY SSF51230 518 593 1.07E-25 T 30-10-2018 IPR011053 Single hybrid motif CL1_1805 7ce8c8b7b58acb13270426e78859c615 593 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 549 566 - T 30-10-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CL1_1805 7ce8c8b7b58acb13270426e78859c615 593 Pfam PF02436 Conserved carboxylase domain 292 474 1.9E-55 T 30-10-2018 IPR003379 Carboxylase, conserved domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 CL1_1805 7ce8c8b7b58acb13270426e78859c615 593 SUPERFAMILY SSF89000 297 446 1.06E-52 T 30-10-2018 CL1_1805 7ce8c8b7b58acb13270426e78859c615 593 Gene3D G3DSA:2.40.50.100 520 593 3.9E-28 T 30-10-2018 CL1_1805 7ce8c8b7b58acb13270426e78859c615 593 SUPERFAMILY SSF51569 2 301 4.03E-86 T 30-10-2018 CL1_1805 7ce8c8b7b58acb13270426e78859c615 593 Pfam PF00682 HMGL-like 3 234 4.8E-41 T 30-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 CL1_1805 7ce8c8b7b58acb13270426e78859c615 593 Gene3D G3DSA:3.20.20.70 1 457 2.9E-165 T 30-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CL1_1770 b776b89aca551e9af0f61798130260f8 398 Pfam PF00465 Iron-containing alcohol dehydrogenase 26 387 3.4E-95 T 30-10-2018 IPR001670 Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 CL1_1770 b776b89aca551e9af0f61798130260f8 398 Gene3D G3DSA:1.20.1090.10 205 398 5.8E-52 T 30-10-2018 CL1_1770 b776b89aca551e9af0f61798130260f8 398 Gene3D G3DSA:3.40.50.1970 18 203 7.1E-42 T 30-10-2018 CL1_1770 b776b89aca551e9af0f61798130260f8 398 SUPERFAMILY SSF56796 21 397 9.16E-95 T 30-10-2018 CL1_0987 83d6d69002ea854bf57f74e49120a40b 70 Pfam PF10049 Protein of unknown function (DUF2283) 3 50 1.4E-17 T 30-10-2018 IPR019270 Protein of unknown function DUF2283 CL1_0269 0c2b2200bb539ea1b5c42948884972a9 420 TIGRFAM TIGR00375 TIGR00375: TIGR00375 family protein 5 380 9.5E-127 T 30-10-2018 IPR005287 Conserved hypothetical protein CHP00375 CL1_0269 0c2b2200bb539ea1b5c42948884972a9 420 SUPERFAMILY SSF89550 5 227 1.39E-14 T 30-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CL1_0269 0c2b2200bb539ea1b5c42948884972a9 420 Pfam PF13263 PHP-associated 175 225 9.7E-5 T 30-10-2018 CL1_0269 0c2b2200bb539ea1b5c42948884972a9 420 Gene3D G3DSA:3.20.20.140 3 234 2.0E-16 T 30-10-2018 CL1_0471 a5180b87944f6a51db6dd29f8e06484b 188 SUPERFAMILY SSF51182 19 186 1.78E-42 T 30-10-2018 IPR011051 RmlC-like cupin domain superfamily CL1_0471 a5180b87944f6a51db6dd29f8e06484b 188 Pfam PF06560 Glucose-6-phosphate isomerase (GPI) 24 179 8.3E-41 T 30-10-2018 IPR010551 Glucose-6-phosphate isomerase, prokaryote GO:0004347|GO:0005737|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385 CL1_0471 a5180b87944f6a51db6dd29f8e06484b 188 Gene3D G3DSA:2.60.120.10 1 188 3.4E-72 T 30-10-2018 IPR014710 RmlC-like jelly roll fold CL1_0471 a5180b87944f6a51db6dd29f8e06484b 188 PIRSF PIRSF019325 1 188 9.7E-73 T 30-10-2018 IPR016758 Glucose-6-phosphate isomerase, archaea/bacteria GO:0004347|GO:0005506 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385 CL1_0371 0c353bbc6df78b9c674cc33b43c580b1 176 Pfam PF04434 SWIM zinc finger 45 68 8.9E-7 T 30-10-2018 IPR007527 Zinc finger, SWIM-type GO:0008270 CL1_1340 46a1ed8d1b2696f2e4fe4417a1f6092e 249 Gene3D G3DSA:3.30.70.1890 1 121 4.8E-45 T 30-10-2018 CL1_1340 46a1ed8d1b2696f2e4fe4417a1f6092e 249 Gene3D G3DSA:3.30.70.1900 123 242 6.0E-38 T 30-10-2018 CL1_1340 46a1ed8d1b2696f2e4fe4417a1f6092e 249 Pfam PF01881 CRISPR associated protein Cas6 95 238 1.5E-32 T 30-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 CL1_1340 46a1ed8d1b2696f2e4fe4417a1f6092e 249 PIRSF PIRSF005054 1 242 9.8E-65 T 30-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 CL1_1340 46a1ed8d1b2696f2e4fe4417a1f6092e 249 TIGRFAM TIGR01877 cas_cas6: CRISPR-associated endoribonuclease Cas6 50 237 3.9E-44 T 30-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 CL1_1092 92c072b8d602e830975d760b93648f1a 385 TIGRFAM TIGR00451 unchar_dom_2: uncharacterized domain 2 93 161 4.3E-7 T 30-10-2018 IPR004521 Uncharacterised domain CHP00451 GO:0003723 CL1_1092 92c072b8d602e830975d760b93648f1a 385 SMART SM00359 92 166 2.2E-19 T 30-10-2018 IPR002478 PUA domain GO:0003723 CL1_1092 92c072b8d602e830975d760b93648f1a 385 Gene3D G3DSA:2.30.130.10 89 164 5.5E-15 T 30-10-2018 IPR036974 PUA domain superfamily GO:0003723 CL1_1092 92c072b8d602e830975d760b93648f1a 385 SUPERFAMILY SSF88697 91 162 9.94E-17 T 30-10-2018 IPR015947 PUA-like superfamily CL1_1092 92c072b8d602e830975d760b93648f1a 385 Pfam PF01189 16S rRNA methyltransferase RsmB/F 194 383 2.6E-55 T 30-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 CL1_1092 92c072b8d602e830975d760b93648f1a 385 Gene3D G3DSA:3.30.70.3130 2 88 7.0E-13 T 30-10-2018 CL1_1092 92c072b8d602e830975d760b93648f1a 385 Pfam PF17125 N-terminal domain of 16S rRNA methyltransferase RsmF 10 86 8.0E-8 T 30-10-2018 IPR031341 Ribosomal RNA small subunit methyltransferase F, N-terminal Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 CL1_1092 92c072b8d602e830975d760b93648f1a 385 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 176 190 2.6E-25 T 30-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase CL1_1092 92c072b8d602e830975d760b93648f1a 385 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 318 334 2.6E-25 T 30-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase CL1_1092 92c072b8d602e830975d760b93648f1a 385 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 205 215 2.6E-25 T 30-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase CL1_1092 92c072b8d602e830975d760b93648f1a 385 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 271 283 2.6E-25 T 30-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase CL1_1092 92c072b8d602e830975d760b93648f1a 385 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 367 384 2.6E-25 T 30-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase CL1_1092 92c072b8d602e830975d760b93648f1a 385 Pfam PF01472 PUA domain 94 161 2.3E-16 T 30-10-2018 IPR002478 PUA domain GO:0003723 CL1_1092 92c072b8d602e830975d760b93648f1a 385 Gene3D G3DSA:3.40.50.150 191 385 1.5E-60 T 30-10-2018 CL1_1092 92c072b8d602e830975d760b93648f1a 385 SUPERFAMILY SSF53335 8 385 1.64E-54 T 30-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CL1_1652 975e8a99da233b566d076a0348f216f9 348 SUPERFAMILY SSF53187 4 343 2.82E-71 T 30-10-2018 CL1_1652 975e8a99da233b566d076a0348f216f9 348 Pfam PF05343 M42 glutamyl aminopeptidase 45 335 4.6E-111 T 30-10-2018 IPR008007 Peptidase M42 CL1_1652 975e8a99da233b566d076a0348f216f9 348 SUPERFAMILY SSF101821 68 177 2.44E-29 T 30-10-2018 CL1_1652 975e8a99da233b566d076a0348f216f9 348 Gene3D G3DSA:3.40.630.10 6 336 2.4E-136 T 30-10-2018 CL1_1652 975e8a99da233b566d076a0348f216f9 348 Gene3D G3DSA:2.40.30.40 68 161 2.4E-136 T 30-10-2018 IPR023367 Peptidase M42, domain 2 CL1_1652 975e8a99da233b566d076a0348f216f9 348 PIRSF PIRSF001123 1 347 8.0E-122 T 30-10-2018 IPR008007 Peptidase M42 CL1_1339 eaf9c2687ef82eff89a32ae4021ecfb8 398 Hamap MF_00553 Proteasome-activating nucleotidase [pan]. 2 397 47.747 T 30-10-2018 IPR023501 Proteasome-activating nucleotidase PAN CL1_1339 eaf9c2687ef82eff89a32ae4021ecfb8 398 Gene3D G3DSA:1.10.8.60 310 381 6.7E-31 T 30-10-2018 CL1_1339 eaf9c2687ef82eff89a32ae4021ecfb8 398 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 176 309 4.3E-44 T 30-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CL1_1339 eaf9c2687ef82eff89a32ae4021ecfb8 398 TIGRFAM TIGR01242 26Sp45: 26S proteasome subunit P45 family 19 379 1.8E-200 T 30-10-2018 IPR005937 26S proteasome regulatory subunit P45-like GO:0005737|GO:0016787|GO:0030163 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 CL1_1339 eaf9c2687ef82eff89a32ae4021ecfb8 398 Gene3D G3DSA:2.40.50.140 24 128 2.4E-26 T 30-10-2018 CL1_1339 eaf9c2687ef82eff89a32ae4021ecfb8 398 Gene3D G3DSA:3.40.50.300 129 309 3.6E-72 T 30-10-2018 CL1_1339 eaf9c2687ef82eff89a32ae4021ecfb8 398 SUPERFAMILY SSF52540 134 385 6.18E-74 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_1339 eaf9c2687ef82eff89a32ae4021ecfb8 398 SMART SM00382 172 311 9.7E-25 T 30-10-2018 IPR003593 AAA+ ATPase domain CL1_1339 eaf9c2687ef82eff89a32ae4021ecfb8 398 Pfam PF16450 Proteasomal ATPase OB/ID domain 65 122 7.6E-8 T 30-10-2018 IPR032501 Proteasomal ATPase, OB/ID domain CL1_1339 eaf9c2687ef82eff89a32ae4021ecfb8 398 ProSitePatterns PS00674 AAA-protein family signature. 279 297 - T 30-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 CL1_1094 6da5ccabdc5006015a6ee7866010e4d7 301 Gene3D G3DSA:2.60.40.10 164 295 1.3E-29 T 30-10-2018 IPR013783 Immunoglobulin-like fold CL1_1094 6da5ccabdc5006015a6ee7866010e4d7 301 Gene3D G3DSA:2.60.40.10 30 144 1.4E-10 T 30-10-2018 IPR013783 Immunoglobulin-like fold CL1_1094 6da5ccabdc5006015a6ee7866010e4d7 301 SUPERFAMILY SSF117070 160 265 4.71E-15 T 30-10-2018 CL1_1094 6da5ccabdc5006015a6ee7866010e4d7 301 SMART SM00769 165 282 2.4E-8 T 30-10-2018 IPR013990 Water stress and hypersensitive response domain GO:0009269 CL1_1094 6da5ccabdc5006015a6ee7866010e4d7 301 Pfam PF03168 Late embryogenesis abundant protein 189 264 1.0E-8 T 30-10-2018 IPR004864 Late embryogenesis abundant protein, LEA_2 subgroup CL1_0859 ddffb5e27970ca6e2ed8e6d6c045b404 775 Gene3D G3DSA:3.40.50.12610 475 568 2.9E-8 T 30-10-2018 CL1_0874 e97232a06788d8c8ff0eecc2412355ea 1065 Gene3D G3DSA:3.90.740.10 199 405 3.1E-230 T 30-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 CL1_0874 e97232a06788d8c8ff0eecc2412355ea 1065 SUPERFAMILY SSF50677 203 401 1.26E-55 T 30-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 CL1_0874 e97232a06788d8c8ff0eecc2412355ea 1065 Pfam PF08264 Anticodon-binding domain of tRNA 711 860 2.8E-37 T 30-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 CL1_0874 e97232a06788d8c8ff0eecc2412355ea 1065 Hamap MF_02003 Isoleucine--tRNA ligase [ileS]. 3 1059 13.728 T 30-10-2018 IPR023586 Isoleucine-tRNA ligase, type 2 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CL1_0874 e97232a06788d8c8ff0eecc2412355ea 1065 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 9 875 0.0 T 30-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CL1_0874 e97232a06788d8c8ff0eecc2412355ea 1065 Gene3D G3DSA:1.10.730.10 669 853 2.3E-54 T 30-10-2018 CL1_0874 e97232a06788d8c8ff0eecc2412355ea 1065 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 42 53 5.2E-30 T 30-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CL1_0874 e97232a06788d8c8ff0eecc2412355ea 1065 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 545 558 5.2E-30 T 30-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CL1_0874 e97232a06788d8c8ff0eecc2412355ea 1065 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 223 246 5.2E-30 T 30-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CL1_0874 e97232a06788d8c8ff0eecc2412355ea 1065 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 584 593 5.2E-30 T 30-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CL1_0874 e97232a06788d8c8ff0eecc2412355ea 1065 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 399 414 5.2E-30 T 30-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CL1_0874 e97232a06788d8c8ff0eecc2412355ea 1065 SUPERFAMILY SSF52374 2 674 7.59E-134 T 30-10-2018 CL1_0874 e97232a06788d8c8ff0eecc2412355ea 1065 SUPERFAMILY SSF47323 676 912 3.74E-61 T 30-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CL1_0874 e97232a06788d8c8ff0eecc2412355ea 1065 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 21 663 1.5E-188 T 30-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 CL1_0874 e97232a06788d8c8ff0eecc2412355ea 1065 Gene3D G3DSA:3.40.50.620 16 651 3.1E-230 T 30-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CL1_0874 e97232a06788d8c8ff0eecc2412355ea 1065 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 49 60 - T 30-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CL1_1184 aa3160b3d138d8e7249f26380d00c4f2 83 SUPERFAMILY SSF158436 3 83 5.23E-30 T 30-10-2018 CL1_1184 aa3160b3d138d8e7249f26380d00c4f2 83 ProDom PD029943 UPF0147 ARCHAEAL PF0239 ST0460.1 MM1385 CYTOSOLIC SACI_0891 TV0625 APES069 TA0600 1 83 2.0E-39 T 30-10-2018 IPR005354 Uncharacterised protein family UPF0147 CL1_1184 aa3160b3d138d8e7249f26380d00c4f2 83 Pfam PF03685 Uncharacterised protein family (UPF0147) 2 82 2.4E-33 T 30-10-2018 IPR005354 Uncharacterised protein family UPF0147 CL1_1184 aa3160b3d138d8e7249f26380d00c4f2 83 Hamap MF_00342 UPF0147 protein . 1 83 29.722 T 30-10-2018 IPR005354 Uncharacterised protein family UPF0147 CL1_1184 aa3160b3d138d8e7249f26380d00c4f2 83 Gene3D G3DSA:1.20.1440.50 1 83 3.0E-31 T 30-10-2018 IPR023130 Ta0600-like superfamily CL1_1595 155f3e9b458243e3dfd3de6a25e4e391 234 PIRSF PIRSF005928 10 232 2.8E-102 T 30-10-2018 IPR009185 Predicted nucleotidyltransferase CL1_1595 155f3e9b458243e3dfd3de6a25e4e391 234 Pfam PF01909 Nucleotidyltransferase domain 31 73 2.9E-7 T 30-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 CL1_1595 155f3e9b458243e3dfd3de6a25e4e391 234 SUPERFAMILY SSF81301 20 73 8.0E-9 T 30-10-2018 CL1_1595 155f3e9b458243e3dfd3de6a25e4e391 234 Gene3D G3DSA:3.30.460.10 20 92 1.4E-7 T 30-10-2018 CL1_1391 c5a536405e1785eaf6936aeb913eec90 93 SUPERFAMILY SSF111057 1 92 5.89E-33 T 30-10-2018 IPR036216 Hypothetical protein UCP004604 superfamily CL1_1391 c5a536405e1785eaf6936aeb913eec90 93 PIRSF PIRSF004604 1 93 2.6E-22 T 30-10-2018 IPR014418 Uncharacterised conserved protein UCP004604 CL1_1391 c5a536405e1785eaf6936aeb913eec90 93 ProDom PD029791 ORF 3'REGION GAP PF1875 PF0899 PH1831 B PHS036 2 92 6.0E-28 T 30-10-2018 IPR014418 Uncharacterised conserved protein UCP004604 CL1_1391 c5a536405e1785eaf6936aeb913eec90 93 Gene3D G3DSA:3.30.2320.10 1 93 3.9E-28 T 30-10-2018 CL1_1391 c5a536405e1785eaf6936aeb913eec90 93 Pfam PF08967 Domain of unknown function (DUF1884) 2 92 3.0E-40 T 30-10-2018 IPR014418 Uncharacterised conserved protein UCP004604 CL1_1258 b53f6b2e2e2144f379ccfde8c03163b1 235 Gene3D G3DSA:3.40.1280.10 1 154 1.8E-48 T 30-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CL1_1258 b53f6b2e2e2144f379ccfde8c03163b1 235 PIRSF PIRSF004808 1 232 1.9E-72 T 30-10-2018 IPR004384 RNA methyltransferase TrmJ/LasT GO:0006396|GO:0008173 CL1_1258 b53f6b2e2e2144f379ccfde8c03163b1 235 Pfam PF00588 SpoU rRNA Methylase family 1 147 5.3E-32 T 30-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 CL1_1258 b53f6b2e2e2144f379ccfde8c03163b1 235 TIGRFAM TIGR00050 rRNA_methyl_1: RNA methyltransferase, TrmH family, group 1 1 222 5.1E-60 T 30-10-2018 IPR004384 RNA methyltransferase TrmJ/LasT GO:0006396|GO:0008173 CL1_1258 b53f6b2e2e2144f379ccfde8c03163b1 235 SUPERFAMILY SSF75217 1 171 1.5E-32 T 30-10-2018 IPR029028 Alpha/beta knot methyltransferases CL1_1404 cc6112fea501cf19b2ffed01e3c7c6da 386 PIRSF PIRSF000429 1 383 1.1E-62 T 30-10-2018 IPR002155 Thiolase GO:0016747 CL1_1404 cc6112fea501cf19b2ffed01e3c7c6da 386 Pfam PF00108 Thiolase, N-terminal domain 5 220 2.9E-25 T 30-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 CL1_1404 cc6112fea501cf19b2ffed01e3c7c6da 386 SUPERFAMILY SSF53901 247 373 1.54E-28 T 30-10-2018 IPR016039 Thiolase-like GO:0003824 CL1_1404 cc6112fea501cf19b2ffed01e3c7c6da 386 SUPERFAMILY SSF53901 4 229 4.76E-44 T 30-10-2018 IPR016039 Thiolase-like GO:0003824 CL1_1404 cc6112fea501cf19b2ffed01e3c7c6da 386 Pfam PF02803 Thiolase, C-terminal domain 250 355 2.3E-10 T 30-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 CL1_1404 cc6112fea501cf19b2ffed01e3c7c6da 386 Gene3D G3DSA:3.40.47.10 4 385 4.5E-123 T 30-10-2018 IPR016039 Thiolase-like GO:0003824 CL1_1884 96e007dedf748a8df22d0c05d2864c3c 268 Pfam PF05552 Conserved TM helix 17 48 2.4E-7 T 30-10-2018 IPR008910 Conserved TM helix CL1_1884 96e007dedf748a8df22d0c05d2864c3c 268 SUPERFAMILY SSF82689 168 267 1.7E-34 T 30-10-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 CL1_1884 96e007dedf748a8df22d0c05d2864c3c 268 Pfam PF00924 Mechanosensitive ion channel 59 256 7.7E-52 T 30-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 CL1_1884 96e007dedf748a8df22d0c05d2864c3c 268 SUPERFAMILY SSF82861 16 100 2.35E-12 T 30-10-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 CL1_1884 96e007dedf748a8df22d0c05d2864c3c 268 SUPERFAMILY SSF50182 101 167 4.58E-16 T 30-10-2018 IPR010920 LSM domain superfamily CL1_1884 96e007dedf748a8df22d0c05d2864c3c 268 Gene3D G3DSA:3.30.70.100 167 261 1.0E-30 T 30-10-2018 CL1_1884 96e007dedf748a8df22d0c05d2864c3c 268 Gene3D G3DSA:2.30.30.60 117 166 8.3E-16 T 30-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily CL1_1422 35138ec7072fdde405d3dfca156580b4 261 Pfam PF01040 UbiA prenyltransferase family 22 248 1.3E-33 T 30-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 CL1_1422 35138ec7072fdde405d3dfca156580b4 261 Gene3D G3DSA:1.10.357.140 16 158 3.1E-9 T 30-10-2018 CL1_0761 ef99850110b9efdaf2923d08d386d328 98 Pfam PF01282 Ribosomal protein S24e 21 97 4.1E-27 T 30-10-2018 IPR001976 Ribosomal protein S24e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0761 ef99850110b9efdaf2923d08d386d328 98 SUPERFAMILY SSF54189 1 97 1.44E-32 T 30-10-2018 IPR012678 Ribosomal protein L23/L15e core domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 CL1_0761 ef99850110b9efdaf2923d08d386d328 98 Gene3D G3DSA:3.30.70.330 1 98 6.0E-39 T 30-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily CL1_0761 ef99850110b9efdaf2923d08d386d328 98 Hamap MF_00545 30S ribosomal protein S24e [rps24e]. 1 98 21.429 T 30-10-2018 IPR001976 Ribosomal protein S24e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0761 ef99850110b9efdaf2923d08d386d328 98 ProSitePatterns PS00529 Ribosomal protein S24e signature. 60 82 - T 30-10-2018 IPR018098 Ribosomal S24e conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0761 ef99850110b9efdaf2923d08d386d328 98 ProDom PD006052 RIBOSOMAL S24 40S RIBONUCLEOPROTEIN S24E 30S S24 CDNA RIKEN ACETYLATION 11 76 2.0E-28 T 30-10-2018 IPR001976 Ribosomal protein S24e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_1842 ac84f93c881ff31cb1e98ef9338bb95f 170 Gene3D G3DSA:2.20.28.10 132 170 8.0E-19 T 30-10-2018 CL1_1842 ac84f93c881ff31cb1e98ef9338bb95f 170 SUPERFAMILY SSF57802 136 169 1.99E-10 T 30-10-2018 CL1_1842 ac84f93c881ff31cb1e98ef9338bb95f 170 Pfam PF02915 Rubrerythrin 9 123 3.1E-26 T 30-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 CL1_1842 ac84f93c881ff31cb1e98ef9338bb95f 170 SUPERFAMILY SSF47240 5 131 8.55E-39 T 30-10-2018 IPR009078 Ferritin-like superfamily CL1_1842 ac84f93c881ff31cb1e98ef9338bb95f 170 Gene3D G3DSA:1.20.1260.10 1 131 9.5E-49 T 30-10-2018 IPR012347 Ferritin-like CL1_1675 f0350baa96ffd78e746290308a2bd0a0 145 Pfam PF03551 Transcriptional regulator PadR-like family 5 73 2.5E-16 T 30-10-2018 IPR005149 Transcription regulator PadR, N-terminal CL1_1675 f0350baa96ffd78e746290308a2bd0a0 145 SUPERFAMILY SSF46785 3 126 2.05E-22 T 30-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CL1_1675 f0350baa96ffd78e746290308a2bd0a0 145 Gene3D G3DSA:1.10.10.10 1 93 1.6E-23 T 30-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CL1_0822 5407160600210f1d9b668779894113a9 59 Pfam PF07754 Domain of unknown function (DUF1610) 10 33 2.5E-14 T 30-10-2018 IPR011668 Domain of unknown function DUF1610 CL1_0719 41b2067d04889dbdc1d137c2f914d4e5 355 SUPERFAMILY SSF52540 25 201 8.72E-15 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_0719 41b2067d04889dbdc1d137c2f914d4e5 355 Gene3D G3DSA:3.40.50.300 12 214 4.8E-32 T 30-10-2018 CL1_0719 41b2067d04889dbdc1d137c2f914d4e5 355 Pfam PF16575 mRNA cleavage and polyadenylation factor CLP1 P-loop 34 210 8.9E-44 T 30-10-2018 IPR032319 Polyribonucleotide 5'-hydroxyl-kinase Clp1, P-loop domain CL1_1829 2cafbe03d043e9570451a2060b5b746a 296 Pfam PF13393 Histidyl-tRNA synthetase 4 193 2.2E-17 T 30-10-2018 CL1_1829 2cafbe03d043e9570451a2060b5b746a 296 SUPERFAMILY SSF55681 11 255 1.36E-30 T 30-10-2018 CL1_1829 2cafbe03d043e9570451a2060b5b746a 296 Gene3D G3DSA:3.30.930.10 10 254 2.0E-35 T 30-10-2018 CL1_0007 8379bdc985b0fcf3f93e24da950a0b40 186 Gene3D G3DSA:3.40.920.10 1 185 1.3E-54 T 30-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 CL1_0007 8379bdc985b0fcf3f93e24da950a0b40 186 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 11 176 2.7E-34 T 30-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 CL1_0007 8379bdc985b0fcf3f93e24da950a0b40 186 SUPERFAMILY SSF53323 1 180 5.49E-42 T 30-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 CL1_0007 8379bdc985b0fcf3f93e24da950a0b40 186 TIGRFAM TIGR02175 PorC_KorC: 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate family 4 176 1.7E-23 T 30-10-2018 IPR011894 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate GO:0016625|GO:0055114 CL1_0733 ffe20dc820972eb6c39cbcac43953916 316 SUPERFAMILY SSF48371 22 250 1.98E-18 T 30-10-2018 IPR016024 Armadillo-type fold CL1_0733 ffe20dc820972eb6c39cbcac43953916 316 Gene3D G3DSA:1.25.10.10 1 253 2.9E-64 T 30-10-2018 IPR011989 Armadillo-like helical CL1_1169 6d51ec8a1c71d7e48f9d0f32c15b38f5 215 SUPERFAMILY SSF56112 12 154 2.09E-15 T 30-10-2018 IPR011009 Protein kinase-like domain superfamily CL1_1302 2da835fe9cfec89b51600797492f337b 376 Gene3D G3DSA:3.40.50.1100 43 354 5.2E-102 T 30-10-2018 CL1_1302 2da835fe9cfec89b51600797492f337b 376 SUPERFAMILY SSF53686 3 355 3.67E-85 T 30-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme CL1_1302 2da835fe9cfec89b51600797492f337b 376 TIGRFAM TIGR00260 thrC: threonine synthase 54 351 8.0E-52 T 30-10-2018 IPR004450 Threonine synthase-like CL1_1302 2da835fe9cfec89b51600797492f337b 376 Gene3D G3DSA:3.40.50.1100 91 186 5.2E-102 T 30-10-2018 CL1_1302 2da835fe9cfec89b51600797492f337b 376 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 57 349 3.3E-69 T 30-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme CL1_0931 87b74f435b1590a1d1dba5becf5f611e 102 Hamap MF_00312 V-type ATP synthase subunit F [atpF]. 1 101 19.249 T 30-10-2018 IPR022944 ATPase, V1 complex, subunit F, bacterial/archaeal CL1_0931 87b74f435b1590a1d1dba5becf5f611e 102 Gene3D G3DSA:3.40.50.10580 1 102 4.6E-32 T 30-10-2018 IPR036906 ATPase, V1 complex, subunit F superfamily GO:0034220 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 CL1_0931 87b74f435b1590a1d1dba5becf5f611e 102 SUPERFAMILY SSF159468 3 100 2.88E-19 T 30-10-2018 IPR036906 ATPase, V1 complex, subunit F superfamily GO:0034220 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 CL1_0931 87b74f435b1590a1d1dba5becf5f611e 102 Pfam PF01990 ATP synthase (F/14-kDa) subunit 3 91 4.4E-18 T 30-10-2018 IPR008218 ATPase, V1 complex, subunit F GO:0034220 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 CL1_1713 1c4548235ec381f6485ca69b8756f622 405 SUPERFAMILY SSF51338 12 401 2.62E-22 T 30-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 CL1_1713 1c4548235ec381f6485ca69b8756f622 405 Pfam PF01979 Amidohydrolase family 51 395 5.0E-54 T 30-10-2018 IPR006680 Amidohydrolase-related GO:0016787 CL1_1713 1c4548235ec381f6485ca69b8756f622 405 SUPERFAMILY SSF51556 54 344 3.58E-81 T 30-10-2018 IPR032466 Metal-dependent hydrolase CL1_1713 1c4548235ec381f6485ca69b8756f622 405 Gene3D G3DSA:2.30.40.10 7 400 8.1E-117 T 30-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 CL1_1713 1c4548235ec381f6485ca69b8756f622 405 Gene3D G3DSA:3.20.20.140 55 341 8.1E-117 T 30-10-2018 CL1_0769 e224872dceb431354ef7f8dbd3d6faab 185 Pfam PF04021 Class III signal peptide 5 26 8.7E-6 T 30-10-2018 IPR007166 Class III signal peptide motif CL1_0683 3015c8f39f35a8dc9f9130d0acd7aff1 348 Pfam PF01594 AI-2E family transporter 11 322 3.2E-37 T 30-10-2018 IPR002549 Transmembrane protein TqsA-like CL1_1656 d1c15b9630e0f6d7bb9401ddaa7be326 280 Gene3D G3DSA:1.10.150.130 1 89 3.4E-22 T 30-10-2018 IPR010998 Integrase/recombinase, N-terminal CL1_1656 d1c15b9630e0f6d7bb9401ddaa7be326 280 Hamap MF_02055 Tyrosine recombinase XerA [xerA]. 3 273 43.32 T 30-10-2018 IPR033686 Tyrosine recombinase XerA CL1_1656 d1c15b9630e0f6d7bb9401ddaa7be326 280 Gene3D G3DSA:1.10.443.10 90 279 1.8E-76 T 30-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 CL1_1656 d1c15b9630e0f6d7bb9401ddaa7be326 280 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 7 77 2.3E-9 T 30-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 CL1_1656 d1c15b9630e0f6d7bb9401ddaa7be326 280 SUPERFAMILY SSF56349 5 269 1.56E-60 T 30-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CL1_1656 d1c15b9630e0f6d7bb9401ddaa7be326 280 Pfam PF00589 Phage integrase family 98 261 8.1E-49 T 30-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CL1_1009 58f001d73099b17307cdec1650f0cb11 110 Pfam PF04266 ASCH domain 1 103 2.9E-18 T 30-10-2018 IPR007374 ASCH domain CL1_1009 58f001d73099b17307cdec1650f0cb11 110 PIRSF PIRSF016134 1 106 1.7E-45 T 30-10-2018 IPR016645 Uncharacterised conserved protein UCP016134 CL1_1009 58f001d73099b17307cdec1650f0cb11 110 SMART SM01022 1 104 9.9E-17 T 30-10-2018 IPR007374 ASCH domain CL1_1009 58f001d73099b17307cdec1650f0cb11 110 Gene3D G3DSA:2.30.130.30 1 104 7.8E-41 T 30-10-2018 CL1_1009 58f001d73099b17307cdec1650f0cb11 110 SUPERFAMILY SSF88697 1 104 1.01E-34 T 30-10-2018 IPR015947 PUA-like superfamily CL1_0294 56ea5e8745ae5728be0cf2a2f5e8ee7a 295 Pfam PF00557 Metallopeptidase family M24 7 287 6.9E-44 T 30-10-2018 IPR000994 Peptidase M24 CL1_0294 56ea5e8745ae5728be0cf2a2f5e8ee7a 295 Gene3D G3DSA:3.90.230.10 9 286 9.0E-109 T 30-10-2018 CL1_0294 56ea5e8745ae5728be0cf2a2f5e8ee7a 295 SUPERFAMILY SSF55920 2 295 5.1E-67 T 30-10-2018 IPR036005 Creatinase/aminopeptidase-like CL1_0294 56ea5e8745ae5728be0cf2a2f5e8ee7a 295 ProSitePatterns PS01202 Methionine aminopeptidase subfamily 2 signature. 78 94 - T 30-10-2018 IPR018349 Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site MetaCyc: PWY-7799|MetaCyc: PWY-7800 CL1_0294 56ea5e8745ae5728be0cf2a2f5e8ee7a 295 Hamap MF_01975 Methionine aminopeptidase [map]. 4 295 47.814 T 30-10-2018 IPR028595 Methionine aminopeptidase, archaeal GO:0004177|GO:0006508 MetaCyc: PWY-7799|MetaCyc: PWY-7800 CL1_0294 56ea5e8745ae5728be0cf2a2f5e8ee7a 295 SUPERFAMILY SSF46785 196 271 4.08E-17 T 30-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CL1_0294 56ea5e8745ae5728be0cf2a2f5e8ee7a 295 TIGRFAM TIGR00501 met_pdase_II: methionine aminopeptidase, type II 2 295 2.4E-117 T 30-10-2018 IPR002468 Peptidase M24A, methionine aminopeptidase, subfamily 2 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800|Reactome: R-HSA-2514859 CL1_0294 56ea5e8745ae5728be0cf2a2f5e8ee7a 295 PRINTS PR00599 Methionine aminopeptidase-1 signature 145 157 5.9E-16 T 30-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CL1_0294 56ea5e8745ae5728be0cf2a2f5e8ee7a 295 PRINTS PR00599 Methionine aminopeptidase-1 signature 53 66 5.9E-16 T 30-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CL1_0294 56ea5e8745ae5728be0cf2a2f5e8ee7a 295 PRINTS PR00599 Methionine aminopeptidase-1 signature 78 94 5.9E-16 T 30-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CL1_0294 56ea5e8745ae5728be0cf2a2f5e8ee7a 295 PRINTS PR00599 Methionine aminopeptidase-1 signature 177 189 5.9E-16 T 30-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CL1_0294 56ea5e8745ae5728be0cf2a2f5e8ee7a 295 Gene3D G3DSA:1.10.10.10 196 272 9.0E-109 T 30-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CL1_0309 0aa71675efeeb798774124db2da98262 196 Gene3D G3DSA:2.20.70.10 156 189 1.5E-16 T 30-10-2018 CL1_0309 0aa71675efeeb798774124db2da98262 196 Hamap MF_00975 Exosome complex component Csl4 [csl4]. 12 193 28.547 T 30-10-2018 IPR030850 Exosome complex component Csl4, archaea GO:0000178|GO:0006396 CL1_0309 0aa71675efeeb798774124db2da98262 196 Pfam PF10447 Exosome component EXOSC1/CSL4 66 123 2.5E-4 T 30-10-2018 IPR019495 Exosome complex component CSL4, C-terminal GO:0000178|GO:0003723 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CL1_0309 0aa71675efeeb798774124db2da98262 196 Pfam PF14382 Exosome complex exonuclease RRP4 N-terminal region 12 48 7.0E-7 T 30-10-2018 IPR025721 Exosome complex component, N-terminal domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CL1_0309 0aa71675efeeb798774124db2da98262 196 SUPERFAMILY SSF50249 64 186 3.9E-29 T 30-10-2018 IPR012340 Nucleic acid-binding, OB-fold CL1_0309 0aa71675efeeb798774124db2da98262 196 Gene3D G3DSA:2.40.50.140 65 155 6.8E-24 T 30-10-2018 CL1_0309 0aa71675efeeb798774124db2da98262 196 SUPERFAMILY SSF110324 11 63 2.3E-12 T 30-10-2018 CL1_0309 0aa71675efeeb798774124db2da98262 196 SMART SM00316 68 149 1.1E-9 T 30-10-2018 IPR022967 RNA-binding domain, S1 CL1_0309 0aa71675efeeb798774124db2da98262 196 Gene3D G3DSA:2.40.50.100 11 60 1.2E-16 T 30-10-2018 CL1_1857 aa7531ce4c67d971b1b4a93526ee4bd5 283 Gene3D G3DSA:3.40.50.300 1 231 5.8E-61 T 30-10-2018 CL1_1857 aa7531ce4c67d971b1b4a93526ee4bd5 283 SMART SM00382 28 214 1.6E-11 T 30-10-2018 IPR003593 AAA+ ATPase domain CL1_1857 aa7531ce4c67d971b1b4a93526ee4bd5 283 ProSitePatterns PS00211 ABC transporters family signature. 130 144 - T 30-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CL1_1857 aa7531ce4c67d971b1b4a93526ee4bd5 283 Pfam PF00005 ABC transporter 20 157 2.0E-27 T 30-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CL1_1857 aa7531ce4c67d971b1b4a93526ee4bd5 283 SUPERFAMILY SSF52540 2 220 1.31E-59 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_1423 72ad2b8f267e4f6541da3041475cc4d8 288 Hamap MF_00198 Polyamine aminopropyltransferase [speE]. 8 286 36.237 T 30-10-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 CL1_1423 72ad2b8f267e4f6541da3041475cc4d8 288 SUPERFAMILY SSF53335 9 286 4.57E-74 T 30-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CL1_1423 72ad2b8f267e4f6541da3041475cc4d8 288 TIGRFAM TIGR00417 speE: spermidine synthase 10 280 7.0E-79 T 30-10-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 CL1_1423 72ad2b8f267e4f6541da3041475cc4d8 288 Gene3D G3DSA:2.30.140.10 6 60 5.2E-24 T 30-10-2018 IPR037163 Spermidine synthase, tetramerisation domain superfamily KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 CL1_1423 72ad2b8f267e4f6541da3041475cc4d8 288 Pfam PF17284 Spermidine synthase tetramerisation domain 10 60 2.4E-13 T 30-10-2018 IPR035246 Spermidine synthase, tetramerisation domain KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 CL1_1423 72ad2b8f267e4f6541da3041475cc4d8 288 Pfam PF01564 Spermine/spermidine synthase domain 64 247 1.5E-47 T 30-10-2018 CL1_1423 72ad2b8f267e4f6541da3041475cc4d8 288 ProSitePatterns PS01330 Polyamine biosynthesis (PABS) domain signature. 84 97 - T 30-10-2018 IPR030373 Polyamine biosynthesis domain, conserved site KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 CL1_1423 72ad2b8f267e4f6541da3041475cc4d8 288 Gene3D G3DSA:3.40.50.150 62 288 2.1E-76 T 30-10-2018 CL1_0676 aa1cd9a6b3d080724692bfe4e4cbdd00 106 Pfam PF12643 MazG-like family 30 105 3.9E-22 T 30-10-2018 IPR025984 dCTP pyrophosphatase 1 GO:0009143|GO:0047429 KEGG: 00240+3.6.1.12|Reactome: R-HSA-499943 CL1_0676 aa1cd9a6b3d080724692bfe4e4cbdd00 106 Gene3D G3DSA:1.10.287.1080 1 106 1.5E-33 T 30-10-2018 CL1_0676 aa1cd9a6b3d080724692bfe4e4cbdd00 106 SUPERFAMILY SSF101386 1 105 4.36E-33 T 30-10-2018 CL1_0676 aa1cd9a6b3d080724692bfe4e4cbdd00 106 PIRSF PIRSF029826 1 106 1.2E-40 T 30-10-2018 IPR025984 dCTP pyrophosphatase 1 GO:0009143|GO:0047429 KEGG: 00240+3.6.1.12|Reactome: R-HSA-499943 CL1_0928 0f5d339aad0fb4b4e745e2b3b008d57f 217 Pfam PF01813 ATP synthase subunit D 13 206 9.4E-63 T 30-10-2018 IPR002699 ATPase, V1 complex, subunit D GO:0042626 Reactome: R-HSA-1222556|Reactome: R-HSA-6798695|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 CL1_0928 0f5d339aad0fb4b4e745e2b3b008d57f 217 Hamap MF_00271 V-type ATP synthase subunit D [atpD]. 4 211 25.783 T 30-10-2018 IPR002699 ATPase, V1 complex, subunit D GO:0042626 Reactome: R-HSA-1222556|Reactome: R-HSA-6798695|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 CL1_0928 0f5d339aad0fb4b4e745e2b3b008d57f 217 TIGRFAM TIGR00309 V_ATPase_subD: V-type ATPase, D subunit 6 209 7.4E-73 T 30-10-2018 IPR002699 ATPase, V1 complex, subunit D GO:0042626 Reactome: R-HSA-1222556|Reactome: R-HSA-6798695|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 CL1_0626 2ea276a6bbbe9d21ec24438b18a641ff 86 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 4 82 14.626 T 30-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 CL1_0626 2ea276a6bbbe9d21ec24438b18a641ff 86 ProSitePatterns PS00050 Ribosomal protein L23 signature. 64 79 - T 30-10-2018 IPR001014 Ribosomal protein L23/L25, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0626 2ea276a6bbbe9d21ec24438b18a641ff 86 Gene3D G3DSA:3.30.70.330 1 86 5.1E-37 T 30-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily CL1_0626 2ea276a6bbbe9d21ec24438b18a641ff 86 TIGRFAM TIGR03636 uL23_arch: ribosomal protein uL23 10 86 1.7E-39 T 30-10-2018 IPR019985 Ribosomal protein L23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0626 2ea276a6bbbe9d21ec24438b18a641ff 86 SUPERFAMILY SSF54189 4 78 9.71E-28 T 30-10-2018 IPR012678 Ribosomal protein L23/L15e core domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 CL1_0626 2ea276a6bbbe9d21ec24438b18a641ff 86 Hamap MF_01369_A 50S ribosomal protein L23 [rplW]. 6 86 27.85 T 30-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 CL1_0626 2ea276a6bbbe9d21ec24438b18a641ff 86 Pfam PF00276 Ribosomal protein L23 5 73 3.5E-19 T 30-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 CL1_1042 624af2a0a3a69af87fde68c37bfb00b6 480 Pfam PF01256 Carbohydrate kinase 227 470 2.4E-51 T 30-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 CL1_1042 624af2a0a3a69af87fde68c37bfb00b6 480 Hamap MF_01966 NAD(P)H-hydrate epimerase [nnrE]. 1 198 18.848 T 30-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 CL1_1042 624af2a0a3a69af87fde68c37bfb00b6 480 TIGRFAM TIGR00197 yjeF_nterm: YjeF family N-terminal domain 8 183 7.0E-43 T 30-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 CL1_1042 624af2a0a3a69af87fde68c37bfb00b6 480 Gene3D G3DSA:3.40.1190.20 210 477 2.2E-75 T 30-10-2018 IPR029056 Ribokinase-like CL1_1042 624af2a0a3a69af87fde68c37bfb00b6 480 Gene3D G3DSA:3.40.50.10260 8 205 9.0E-43 T 30-10-2018 IPR036652 YjeF N-terminal domain superfamily MetaCyc: PWY-6938 CL1_1042 624af2a0a3a69af87fde68c37bfb00b6 480 SUPERFAMILY SSF53613 212 473 5.39E-61 T 30-10-2018 IPR029056 Ribokinase-like CL1_1042 624af2a0a3a69af87fde68c37bfb00b6 480 ProSitePatterns PS01050 YjeF C-terminal domain signature 2. 415 425 - T 30-10-2018 IPR017953 Carbohydrate kinase, predicted, conserved site CL1_1042 624af2a0a3a69af87fde68c37bfb00b6 480 Pfam PF03853 YjeF-related protein N-terminus 22 182 6.6E-34 T 30-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 CL1_1042 624af2a0a3a69af87fde68c37bfb00b6 480 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 204 479 21.074 T 30-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 CL1_1042 624af2a0a3a69af87fde68c37bfb00b6 480 SUPERFAMILY SSF64153 4 225 3.79E-49 T 30-10-2018 IPR036652 YjeF N-terminal domain superfamily MetaCyc: PWY-6938 CL1_1042 624af2a0a3a69af87fde68c37bfb00b6 480 PIRSF PIRSF017184 1 479 9.5E-97 T 30-10-2018 IPR030677 Bifunctional NAD(P)H-hydrate repair enzyme Nnr GO:0052855 MetaCyc: PWY-6938 CL1_1042 624af2a0a3a69af87fde68c37bfb00b6 480 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 211 474 1.7E-70 T 30-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 CL1_1943 dc28a4ca08f2c3ffb7299e38beaff5b4 135 SMART SM00116 78 125 6.7E-10 T 30-10-2018 IPR000644 CBS domain CL1_1943 dc28a4ca08f2c3ffb7299e38beaff5b4 135 SMART SM00116 14 61 1.8E-10 T 30-10-2018 IPR000644 CBS domain CL1_1943 dc28a4ca08f2c3ffb7299e38beaff5b4 135 Gene3D G3DSA:3.10.580.10 1 135 2.6E-45 T 30-10-2018 CL1_1943 dc28a4ca08f2c3ffb7299e38beaff5b4 135 SUPERFAMILY SSF54631 4 123 1.1E-31 T 30-10-2018 CL1_1943 dc28a4ca08f2c3ffb7299e38beaff5b4 135 Pfam PF00571 CBS domain 71 123 2.2E-14 T 30-10-2018 IPR000644 CBS domain CL1_1943 dc28a4ca08f2c3ffb7299e38beaff5b4 135 Pfam PF00571 CBS domain 10 60 8.2E-10 T 30-10-2018 IPR000644 CBS domain CL1_0553 8ac14931858e183239d29a2dd9109f0b 151 Gene3D G3DSA:3.30.1440.10 3 149 6.3E-46 T 30-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0553 8ac14931858e183239d29a2dd9109f0b 151 SUPERFAMILY SSF55282 7 149 1.71E-41 T 30-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0553 8ac14931858e183239d29a2dd9109f0b 151 Pfam PF01877 RNA binding 9 131 2.4E-38 T 30-10-2018 IPR002739 Uncharacterised protein family UPF0201 CL1_1560 1cfb2253dcfd4ca80e96462641644428 235 SUPERFAMILY SSF63999 52 111 9.94E-8 T 30-10-2018 IPR036759 Thiamin pyrophosphokinase, catalytic domain superfamily GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 CL1_1560 1cfb2253dcfd4ca80e96462641644428 235 Hamap MF_02131 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase [mptE]. 7 224 36.62 T 30-10-2018 IPR027510 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, MptE GO:0003848|GO:0005524 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 CL1_1560 1cfb2253dcfd4ca80e96462641644428 235 Pfam PF01973 Protein of unknown function DUF115 51 187 8.5E-26 T 30-10-2018 IPR002826 6-hydroxymethylpterin diphosphokinase MptE-like CL1_1442 5560286f1541a0e0c3655d5967880936 253 PIRSF PIRSF017269 1 253 6.2E-81 T 30-10-2018 IPR014816 tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 GO:0016429|GO:0030488|GO:0031515 MetaCyc: PWY-6829 CL1_1442 5560286f1541a0e0c3655d5967880936 253 Pfam PF08704 tRNA methyltransferase complex GCD14 subunit 74 232 3.1E-27 T 30-10-2018 IPR014816 tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 GO:0016429|GO:0030488|GO:0031515 MetaCyc: PWY-6829 CL1_1442 5560286f1541a0e0c3655d5967880936 253 Pfam PF14801 tRNA methyltransferase complex GCD14 subunit N-term 2 46 1.4E-8 T 30-10-2018 CL1_1442 5560286f1541a0e0c3655d5967880936 253 Gene3D G3DSA:3.10.330.20 1 61 2.0E-25 T 30-10-2018 CL1_1442 5560286f1541a0e0c3655d5967880936 253 SUPERFAMILY SSF53335 2 252 2.81E-78 T 30-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CL1_1442 5560286f1541a0e0c3655d5967880936 253 Gene3D G3DSA:3.40.50.150 63 253 1.4E-67 T 30-10-2018 CL1_1039 e9b921ab4661f2c2283418b7bd9e8cba 185 SUPERFAMILY SSF46785 5 131 6.72E-23 T 30-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CL1_1039 e9b921ab4661f2c2283418b7bd9e8cba 185 Gene3D G3DSA:1.10.10.10 1 85 1.0E-21 T 30-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CL1_1039 e9b921ab4661f2c2283418b7bd9e8cba 185 SMART SM00418 11 87 1.1E-11 T 30-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CL1_1039 e9b921ab4661f2c2283418b7bd9e8cba 185 Pfam PF01022 Bacterial regulatory protein, arsR family 19 63 6.6E-13 T 30-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CL1_1310 194f6611e6b5c0e648f16282d62c0f81 171 PIRSF PIRSF005285 8 171 1.2E-63 T 30-10-2018 IPR016442 tRNA-splicing endonuclease, archaeal short subfamily MetaCyc: PWY-6689|MetaCyc: PWY-7803 CL1_1310 194f6611e6b5c0e648f16282d62c0f81 171 Pfam PF02778 tRNA intron endonuclease, N-terminal domain 8 69 2.6E-20 T 30-10-2018 IPR006678 tRNA intron endonuclease, N-terminal GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803|Reactome: R-HSA-6784531 CL1_1310 194f6611e6b5c0e648f16282d62c0f81 171 SUPERFAMILY SSF55267 6 77 3.53E-19 T 30-10-2018 IPR036740 tRNA intron endonuclease, N-terminal domain superfamily GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803 CL1_1310 194f6611e6b5c0e648f16282d62c0f81 171 Gene3D G3DSA:3.40.1350.10 79 171 2.1E-31 T 30-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 CL1_1310 194f6611e6b5c0e648f16282d62c0f81 171 Hamap MF_01833 tRNA-splicing endonuclease [endA]. 5 171 33.046 T 30-10-2018 IPR016442 tRNA-splicing endonuclease, archaeal short subfamily MetaCyc: PWY-6689|MetaCyc: PWY-7803 CL1_1310 194f6611e6b5c0e648f16282d62c0f81 171 Gene3D G3DSA:3.40.1170.20 8 73 1.1E-17 T 30-10-2018 CL1_1310 194f6611e6b5c0e648f16282d62c0f81 171 TIGRFAM TIGR00324 endA: tRNA-intron lyase 8 169 2.3E-37 T 30-10-2018 IPR006676 tRNA-splicing endonuclease GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803|Reactome: R-HSA-6784531 CL1_1310 194f6611e6b5c0e648f16282d62c0f81 171 Pfam PF01974 tRNA intron endonuclease, catalytic C-terminal domain 80 163 2.8E-29 T 30-10-2018 IPR006677 tRNA intron endonuclease, catalytic domain-like GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803|Reactome: R-HSA-6784531 CL1_1310 194f6611e6b5c0e648f16282d62c0f81 171 SUPERFAMILY SSF53032 79 169 1.7E-28 T 30-10-2018 IPR036167 tRNA intron endonuclease, catalytic domain-like superfamily GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803|Reactome: R-HSA-6784531 CL1_0169 799a49d1efc61f0d84a148adf0cfd2a7 143 Gene3D G3DSA:1.10.10.10 79 143 3.0E-6 T 30-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CL1_0478 939b53a890a9a5412e2e06886a12e27e 340 TIGRFAM TIGR00816 tdt: C4-dicarboxylate transporter/malic acid transport protein 6 330 1.6E-85 T 30-10-2018 IPR011552 Tellurite resistance protein TehA/malic acid transport protein GO:0016021 CL1_0478 939b53a890a9a5412e2e06886a12e27e 340 Pfam PF03595 Voltage-dependent anion channel 6 326 7.3E-69 T 30-10-2018 IPR004695 Voltage-dependent anion channel GO:0016021|GO:0055085 CL1_0478 939b53a890a9a5412e2e06886a12e27e 340 Gene3D G3DSA:1.50.10.150 3 332 3.9E-40 T 30-10-2018 IPR038665 Voltage-dependent anion channel superfamily CL1_2005 41daf60dce68857806c25f867e2794e8 416 SUPERFAMILY SSF109604 2 409 9.92E-90 T 30-10-2018 CL1_2005 41daf60dce68857806c25f867e2794e8 416 SMART SM00471 48 188 1.8E-13 T 30-10-2018 IPR003607 HD/PDEase domain CL1_2005 41daf60dce68857806c25f867e2794e8 416 Gene3D G3DSA:1.10.3210.10 3 287 7.4E-85 T 30-10-2018 CL1_2005 41daf60dce68857806c25f867e2794e8 416 Pfam PF01966 HD domain 52 179 4.6E-16 T 30-10-2018 IPR006674 HD domain CL1_1555 ab62d4f0c001ee15f86a3b8a33f17fc4 150 Pfam PF00782 Dual specificity phosphatase, catalytic domain 32 144 8.5E-16 T 30-10-2018 IPR000340 Dual specificity phosphatase, catalytic domain GO:0008138|GO:0016311 CL1_1555 ab62d4f0c001ee15f86a3b8a33f17fc4 150 SMART SM00195 4 146 1.7E-9 T 30-10-2018 IPR020422 Dual specificity protein phosphatase domain GO:0006470|GO:0008138 CL1_1555 ab62d4f0c001ee15f86a3b8a33f17fc4 150 SUPERFAMILY SSF52799 29 148 2.72E-35 T 30-10-2018 IPR029021 Protein-tyrosine phosphatase-like CL1_1555 ab62d4f0c001ee15f86a3b8a33f17fc4 150 SMART SM00404 52 146 8.2E-5 T 30-10-2018 IPR003595 Protein-tyrosine phosphatase, catalytic CL1_1555 ab62d4f0c001ee15f86a3b8a33f17fc4 150 Gene3D G3DSA:3.90.190.10 6 149 2.4E-33 T 30-10-2018 IPR029021 Protein-tyrosine phosphatase-like CL1_1555 ab62d4f0c001ee15f86a3b8a33f17fc4 150 ProSitePatterns PS00383 Tyrosine specific protein phosphatases active site. 91 101 - T 30-10-2018 IPR016130 Protein-tyrosine phosphatase, active site GO:0004725|GO:0016311 CL1_1103 e4ad319302a91f95da727814d79b93be 310 SUPERFAMILY SSF102114 72 286 1.04E-9 T 30-10-2018 CL1_1103 e4ad319302a91f95da727814d79b93be 310 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 222 302 4.9E-8 T 30-10-2018 IPR023885 4Fe4S-binding SPASM domain CL1_1103 e4ad319302a91f95da727814d79b93be 310 Gene3D G3DSA:3.20.20.70 66 309 1.3E-8 T 30-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CL1_1103 e4ad319302a91f95da727814d79b93be 310 Pfam PF13186 Iron-sulfur cluster-binding domain 225 281 1.4E-4 T 30-10-2018 IPR023885 4Fe4S-binding SPASM domain CL1_0670 0b572ac67764c35700d303685bb49a15 236 SUPERFAMILY SSF54980 157 228 2.3E-22 T 30-10-2018 IPR035647 EF-G domain III/V-like CL1_0670 0b572ac67764c35700d303685bb49a15 236 Gene3D G3DSA:3.30.1250.10 8 87 4.2E-31 T 30-10-2018 IPR036786 Ribosome maturation protein SBDS, N-terminal domain superfamily CL1_0670 0b572ac67764c35700d303685bb49a15 236 Pfam PF09377 SBDS protein C-terminal domain 101 210 7.0E-17 T 30-10-2018 IPR018978 Ribosome maturation protein SBDS, C-terminal GO:0042254 CL1_0670 0b572ac67764c35700d303685bb49a15 236 SUPERFAMILY SSF109728 82 155 6.67E-25 T 30-10-2018 IPR037188 Ribosome maturation protein Sdo1/SBDS, central domain superfamily CL1_0670 0b572ac67764c35700d303685bb49a15 236 TIGRFAM TIGR00291 RNA_SBDS: rRNA metabolism protein, SBDS family 3 231 1.8E-91 T 30-10-2018 IPR002140 Ribosome maturation protein Sdo1/SBDS GO:0042256 CL1_0670 0b572ac67764c35700d303685bb49a15 236 Pfam PF01172 Shwachman-Bodian-Diamond syndrome (SBDS) protein 8 94 1.2E-25 T 30-10-2018 IPR019783 Ribosome maturation protein SBDS, N-terminal CL1_0670 0b572ac67764c35700d303685bb49a15 236 SUPERFAMILY SSF89895 4 87 7.72E-26 T 30-10-2018 IPR036786 Ribosome maturation protein SBDS, N-terminal domain superfamily CL1_0670 0b572ac67764c35700d303685bb49a15 236 ProSitePatterns PS01267 Uncharacterized protein family UPF0023 signature. 37 56 - T 30-10-2018 IPR018023 Ribosome maturation protein SBDS, conserved site CL1_0670 0b572ac67764c35700d303685bb49a15 236 Gene3D G3DSA:1.10.10.900 88 162 2.1E-30 T 30-10-2018 IPR037188 Ribosome maturation protein Sdo1/SBDS, central domain superfamily CL1_0670 0b572ac67764c35700d303685bb49a15 236 Gene3D G3DSA:3.30.70.240 163 235 6.8E-29 T 30-10-2018 CL1_0764 4ca94e1a0b476ff0bd8db2f7d783fe70 196 Gene3D G3DSA:3.40.50.150 3 181 8.4E-39 T 30-10-2018 CL1_0764 4ca94e1a0b476ff0bd8db2f7d783fe70 196 Pfam PF05175 Methyltransferase small domain 22 163 1.2E-18 T 30-10-2018 IPR007848 Methyltransferase small domain GO:0008168 CL1_0764 4ca94e1a0b476ff0bd8db2f7d783fe70 196 SUPERFAMILY SSF53335 4 180 6.81E-41 T 30-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CL1_0764 4ca94e1a0b476ff0bd8db2f7d783fe70 196 TIGRFAM TIGR00537 hemK_rel_arch: putative methylase 15 189 1.7E-60 T 30-10-2018 IPR004557 Eukaryotic/archaeal PrmC-related GO:0008276 Reactome: R-HSA-156581|Reactome: R-HSA-72764 CL1_1355 43dcce0c50cab4e2748963d15619e0d4 390 Gene3D G3DSA:3.90.1170.20 1 106 1.1E-44 T 30-10-2018 IPR037128 Quinolinate phosphoribosyl transferase, N-terminal domain superfamily GO:0016763 Reactome: R-HSA-196807 CL1_1355 43dcce0c50cab4e2748963d15619e0d4 390 SUPERFAMILY SSF54675 2 115 1.01E-32 T 30-10-2018 CL1_1355 43dcce0c50cab4e2748963d15619e0d4 390 Gene3D G3DSA:3.20.20.70 107 297 9.1E-64 T 30-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CL1_1355 43dcce0c50cab4e2748963d15619e0d4 390 PIRSF PIRSF000484 8 72 3.7 T 30-10-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 CL1_1355 43dcce0c50cab4e2748963d15619e0d4 390 PIRSF PIRSF000484 59 387 9.4E-50 T 30-10-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 CL1_1355 43dcce0c50cab4e2748963d15619e0d4 390 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 115 303 8.9E-28 T 30-10-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 Reactome: R-HSA-196807 CL1_1355 43dcce0c50cab4e2748963d15619e0d4 390 Gene3D G3DSA:3.20.140.10 299 388 6.6E-6 T 30-10-2018 CL1_1355 43dcce0c50cab4e2748963d15619e0d4 390 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 52 113 2.3E-6 T 30-10-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 CL1_1355 43dcce0c50cab4e2748963d15619e0d4 390 SUPERFAMILY SSF51690 112 386 1.06E-76 T 30-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 CL1_0692 80e5167e8846f0e4cb5fddf3054617be 741 SUPERFAMILY SSF50249 121 198 1.17E-12 T 30-10-2018 IPR012340 Nucleic acid-binding, OB-fold CL1_0692 80e5167e8846f0e4cb5fddf3054617be 741 SUPERFAMILY SSF57938 4 32 3.66E-5 T 30-10-2018 IPR036410 Heat shock protein DnaJ, cysteine-rich domain superfamily CL1_0692 80e5167e8846f0e4cb5fddf3054617be 741 Gene3D G3DSA:2.10.230.20 2 41 1.2E-5 T 30-10-2018 CL1_0692 80e5167e8846f0e4cb5fddf3054617be 741 Gene3D G3DSA:2.40.50.140 128 202 2.1E-14 T 30-10-2018 CL1_0692 80e5167e8846f0e4cb5fddf3054617be 741 SMART SM00316 131 196 2.7E-15 T 30-10-2018 IPR022967 RNA-binding domain, S1 CL1_0692 80e5167e8846f0e4cb5fddf3054617be 741 Pfam PF00575 S1 RNA binding domain 131 193 1.6E-11 T 30-10-2018 IPR003029 S1 domain GO:0003676 CL1_0692 80e5167e8846f0e4cb5fddf3054617be 741 SUPERFAMILY SSF64182 337 734 6.8E-41 T 30-10-2018 IPR038763 DHH phosphoesterase superfamily CL1_0692 80e5167e8846f0e4cb5fddf3054617be 741 Gene3D G3DSA:2.40.50.140 218 304 5.1E-7 T 30-10-2018 CL1_0692 80e5167e8846f0e4cb5fddf3054617be 741 Pfam PF01336 OB-fold nucleic acid binding domain 227 296 3.7E-10 T 30-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 CL1_0692 80e5167e8846f0e4cb5fddf3054617be 741 SUPERFAMILY SSF50249 225 296 2.48E-10 T 30-10-2018 IPR012340 Nucleic acid-binding, OB-fold CL1_0692 80e5167e8846f0e4cb5fddf3054617be 741 Gene3D G3DSA:3.90.1640.30 332 536 1.5E-8 T 30-10-2018 CL1_1787 88f5ae7efc4f3587aca4694ca8f70aa5 158 Pfam PF10007 Uncharacterized protein conserved in archaea (DUF2250) 2 86 1.1E-31 T 30-10-2018 IPR019254 Protein of unknown function DUF2250 CL1_1357 7f4ea5e681dfb5fdca56807bf0763851 300 SUPERFAMILY SSF56281 1 263 7.73E-16 T 30-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like CL1_1357 7f4ea5e681dfb5fdca56807bf0763851 300 Gene3D G3DSA:3.60.15.10 7 273 4.9E-15 T 30-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like CL1_1357 7f4ea5e681dfb5fdca56807bf0763851 300 Hamap MF_01406 UPF0282 protein . 1 286 39.474 T 30-10-2018 IPR014426 Uncharacterised protein family UPF0282, hydrolase, metallo-beta-lactamase CL1_1357 7f4ea5e681dfb5fdca56807bf0763851 300 Pfam PF12706 Beta-lactamase superfamily domain 27 206 2.6E-7 T 30-10-2018 IPR001279 Metallo-beta-lactamase CL1_1357 7f4ea5e681dfb5fdca56807bf0763851 300 PIRSF PIRSF004944 1 299 6.6E-116 T 30-10-2018 IPR014426 Uncharacterised protein family UPF0282, hydrolase, metallo-beta-lactamase CL1_1481 f88524e829026901bd5e77a402ab34c1 169 Pfam PF00293 NUDIX domain 46 163 5.6E-23 T 30-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CL1_1481 f88524e829026901bd5e77a402ab34c1 169 ProSitePatterns PS00893 Nudix box signature. 75 96 - T 30-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CL1_1481 f88524e829026901bd5e77a402ab34c1 169 Gene3D G3DSA:3.90.79.10 40 167 1.1E-41 T 30-10-2018 CL1_1481 f88524e829026901bd5e77a402ab34c1 169 PRINTS PR00502 NUDIX hydrolase family signature 84 99 4.4E-8 T 30-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CL1_1481 f88524e829026901bd5e77a402ab34c1 169 PRINTS PR00502 NUDIX hydrolase family signature 70 84 4.4E-8 T 30-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CL1_1481 f88524e829026901bd5e77a402ab34c1 169 SUPERFAMILY SSF55811 34 166 1.9E-33 T 30-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 CL1_1867 d7e84b2790158572e1851bcc864fa242 110 SUPERFAMILY SSF57783 1 34 9.18E-6 T 30-10-2018 CL1_1867 d7e84b2790158572e1851bcc864fa242 110 Pfam PF02150 RNA polymerases M/15 Kd subunit 1 33 1.6E-14 T 30-10-2018 IPR001529 DNA-directed RNA polymerase, M/15kDa subunit GO:0006351 CL1_1867 d7e84b2790158572e1851bcc864fa242 110 PIRSF PIRSF005586 1 110 3.8E-37 T 30-10-2018 IPR012164 DNA-directed RNA polymerase subunit/transcription factor S GO:0006351 CL1_1867 d7e84b2790158572e1851bcc864fa242 110 SUPERFAMILY SSF57783 47 109 7.65E-24 T 30-10-2018 CL1_1867 d7e84b2790158572e1851bcc864fa242 110 Gene3D G3DSA:2.20.25.10 55 110 1.3E-28 T 30-10-2018 CL1_1867 d7e84b2790158572e1851bcc864fa242 110 ProSitePatterns PS00466 Zinc finger TFIIS-type signature. 71 106 - T 30-10-2018 IPR001222 Zinc finger, TFIIS-type GO:0003676|GO:0006351|GO:0008270 CL1_1867 d7e84b2790158572e1851bcc864fa242 110 TIGRFAM TIGR01384 TFS_arch: transcription factor S 2 110 6.5E-38 T 30-10-2018 IPR006288 Transcription factor S GO:0006355 CL1_1867 d7e84b2790158572e1851bcc864fa242 110 Pfam PF01096 Transcription factor S-II (TFIIS) 70 107 1.3E-21 T 30-10-2018 IPR001222 Zinc finger, TFIIS-type GO:0003676|GO:0006351|GO:0008270 CL1_1867 d7e84b2790158572e1851bcc864fa242 110 SMART SM00440 69 108 6.1E-24 T 30-10-2018 IPR001222 Zinc finger, TFIIS-type GO:0003676|GO:0006351|GO:0008270 CL1_1867 d7e84b2790158572e1851bcc864fa242 110 SMART SM00661 2 56 7.9E-14 T 30-10-2018 IPR001529 DNA-directed RNA polymerase, M/15kDa subunit GO:0006351 CL1_1867 d7e84b2790158572e1851bcc864fa242 110 ProSitePatterns PS01030 RNA polymerases M / 15 Kd subunits signature. 3 25 - T 30-10-2018 IPR019761 DNA-directed RNA polymerase M, 15kDa subunit, conserved site CL1_1299 a29973289304d5d4cc7be1281d8ccacb 449 Gene3D G3DSA:3.40.50.300 211 304 1.5E-7 T 30-10-2018 CL1_1299 a29973289304d5d4cc7be1281d8ccacb 449 Gene3D G3DSA:3.40.50.720 3 132 3.5E-8 T 30-10-2018 CL1_1299 a29973289304d5d4cc7be1281d8ccacb 449 SUPERFAMILY SSF52540 125 295 8.18E-12 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_1299 a29973289304d5d4cc7be1281d8ccacb 449 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 241 299 4.2E-5 T 30-10-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain CL1_1813 ce42c301cc6daadb6ee6fb217f265f2f 85 TIGRFAM TIGR01573 cas2: CRISPR-associated endonuclease Cas2 1 67 4.0E-13 T 30-10-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 CL1_1813 ce42c301cc6daadb6ee6fb217f265f2f 85 Pfam PF09827 CRISPR associated protein Cas2 1 69 4.1E-20 T 30-10-2018 IPR019199 Virulence-associated protein D / CRISPR associated protein Cas2 CL1_1813 ce42c301cc6daadb6ee6fb217f265f2f 85 Hamap MF_01471 CRISPR-associated endoribonuclease Cas2 [cas2]. 1 85 13.996 T 30-10-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 CL1_1813 ce42c301cc6daadb6ee6fb217f265f2f 85 SUPERFAMILY SSF143430 1 77 3.27E-22 T 30-10-2018 CL1_1813 ce42c301cc6daadb6ee6fb217f265f2f 85 Gene3D G3DSA:3.30.70.240 1 64 4.1E-26 T 30-10-2018 CL1_1183 8ea0a067b548245583727fcab4bf4162 175 PIRSF PIRSF015617 1 175 1.1E-62 T 30-10-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17 CL1_1183 8ea0a067b548245583727fcab4bf4162 175 TIGRFAM TIGR00708 cobA: cob(I)yrinic acid a,c-diamide adenosyltransferase 3 175 5.2E-70 T 30-10-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17 CL1_1183 8ea0a067b548245583727fcab4bf4162 175 Gene3D G3DSA:3.40.50.300 1 175 6.8E-66 T 30-10-2018 CL1_1183 8ea0a067b548245583727fcab4bf4162 175 Pfam PF02572 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP 8 175 2.8E-62 T 30-10-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17 CL1_1183 8ea0a067b548245583727fcab4bf4162 175 SUPERFAMILY SSF52540 4 175 4.07E-57 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_0971 bd815bc9e30bb94b88ff79de4012ea23 980 SUPERFAMILY SSF49344 784 926 1.29E-5 T 30-10-2018 CL1_0971 bd815bc9e30bb94b88ff79de4012ea23 980 Gene3D G3DSA:3.40.50.200 488 661 2.1E-24 T 30-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 CL1_0971 bd815bc9e30bb94b88ff79de4012ea23 980 Pfam PF00082 Subtilase family 535 649 3.6E-11 T 30-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CL1_0971 bd815bc9e30bb94b88ff79de4012ea23 980 SUPERFAMILY SSF52743 216 657 1.44E-36 T 30-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 CL1_0971 bd815bc9e30bb94b88ff79de4012ea23 980 Gene3D G3DSA:3.40.50.200 214 437 5.6E-15 T 30-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 CL1_0971 bd815bc9e30bb94b88ff79de4012ea23 980 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 599 609 - T 30-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site CL1_1931 641176bc934749ea27d011f168c2ccfa 428 Gene3D G3DSA:3.40.50.300 1 212 4.8E-86 T 30-10-2018 CL1_1931 641176bc934749ea27d011f168c2ccfa 428 SUPERFAMILY SSF50447 213 315 1.21E-28 T 30-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily CL1_1931 641176bc934749ea27d011f168c2ccfa 428 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 59 74 - T 30-10-2018 IPR031157 Tr-type G domain, conserved site CL1_1931 641176bc934749ea27d011f168c2ccfa 428 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 8 189 7.2E-16 T 30-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CL1_1931 641176bc934749ea27d011f168c2ccfa 428 TIGRFAM TIGR00483 EF-1_alpha: translation elongation factor EF-1, subunit alpha 1 427 9.5E-211 T 30-10-2018 IPR004539 Translation elongation factor EF1A, eukaryotic/archaeal GO:0003746|GO:0005525|GO:0005737|GO:0006414 Reactome: R-HSA-156842 CL1_1931 641176bc934749ea27d011f168c2ccfa 428 Gene3D G3DSA:2.40.30.10 320 425 9.5E-42 T 30-10-2018 CL1_1931 641176bc934749ea27d011f168c2ccfa 428 Pfam PF00009 Elongation factor Tu GTP binding domain 5 209 8.6E-58 T 30-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CL1_1931 641176bc934749ea27d011f168c2ccfa 428 Pfam PF03144 Elongation factor Tu domain 2 235 306 8.6E-18 T 30-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CL1_1931 641176bc934749ea27d011f168c2ccfa 428 Gene3D G3DSA:2.40.30.10 216 310 2.7E-41 T 30-10-2018 CL1_1931 641176bc934749ea27d011f168c2ccfa 428 SUPERFAMILY SSF50465 321 424 1.01E-39 T 30-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal CL1_1931 641176bc934749ea27d011f168c2ccfa 428 Hamap MF_00118_A Elongation factor Tu [tuf]. 2 427 60.813 T 30-10-2018 IPR004539 Translation elongation factor EF1A, eukaryotic/archaeal GO:0003746|GO:0005525|GO:0005737|GO:0006414 Reactome: R-HSA-156842 CL1_1931 641176bc934749ea27d011f168c2ccfa 428 SUPERFAMILY SSF52540 3 236 3.12E-75 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_1931 641176bc934749ea27d011f168c2ccfa 428 PRINTS PR00315 GTP-binding elongation factor signature 66 74 2.4E-24 T 30-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CL1_1931 641176bc934749ea27d011f168c2ccfa 428 PRINTS PR00315 GTP-binding elongation factor signature 102 113 2.4E-24 T 30-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CL1_1931 641176bc934749ea27d011f168c2ccfa 428 PRINTS PR00315 GTP-binding elongation factor signature 139 148 2.4E-24 T 30-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CL1_1931 641176bc934749ea27d011f168c2ccfa 428 PRINTS PR00315 GTP-binding elongation factor signature 86 96 2.4E-24 T 30-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CL1_1931 641176bc934749ea27d011f168c2ccfa 428 PRINTS PR00315 GTP-binding elongation factor signature 9 22 2.4E-24 T 30-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CL1_1931 641176bc934749ea27d011f168c2ccfa 428 Pfam PF03143 Elongation factor Tu C-terminal domain 317 424 2.2E-37 T 30-10-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal CL1_0522 5d75e74a7a4477999154e6fd6ed97fd1 122 Pfam PF01850 PIN domain 1 109 4.3E-9 T 30-10-2018 IPR002716 PIN domain CL1_0522 5d75e74a7a4477999154e6fd6ed97fd1 122 SUPERFAMILY SSF88723 1 119 6.45E-24 T 30-10-2018 IPR029060 PIN-like domain superfamily CL1_0522 5d75e74a7a4477999154e6fd6ed97fd1 122 Gene3D G3DSA:3.40.50.1010 1 121 5.1E-28 T 30-10-2018 CL1_0522 5d75e74a7a4477999154e6fd6ed97fd1 122 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 1 116 10.686 T 30-10-2018 IPR022907 VapC family GO:0004540 CL1_0196 9c9bbc58e30ce85c059aa80fe3c5ddef 495 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 238 264 1.1E-11 T 30-10-2018 CL1_0196 9c9bbc58e30ce85c059aa80fe3c5ddef 495 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 413 432 1.1E-11 T 30-10-2018 CL1_0196 9c9bbc58e30ce85c059aa80fe3c5ddef 495 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 78 103 1.1E-11 T 30-10-2018 CL1_0196 9c9bbc58e30ce85c059aa80fe3c5ddef 495 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 151 172 1.1E-11 T 30-10-2018 CL1_0196 9c9bbc58e30ce85c059aa80fe3c5ddef 495 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 309 321 1.1E-11 T 30-10-2018 CL1_0196 9c9bbc58e30ce85c059aa80fe3c5ddef 495 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 216 237 1.1E-11 T 30-10-2018 CL1_0196 9c9bbc58e30ce85c059aa80fe3c5ddef 495 Pfam PF00361 Proton-conducting membrane transporter 130 418 5.3E-63 T 30-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CL1_1514 571129d74cd097e6e11fd8f3432399d3 344 Gene3D G3DSA:2.40.50.140 245 343 1.6E-26 T 30-10-2018 CL1_1514 571129d74cd097e6e11fd8f3432399d3 344 SUPERFAMILY SSF50331 235 344 1.08E-22 T 30-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal CL1_1514 571129d74cd097e6e11fd8f3432399d3 344 Gene3D G3DSA:2.40.50.100 268 339 1.6E-26 T 30-10-2018 CL1_1514 571129d74cd097e6e11fd8f3432399d3 344 SUPERFAMILY SSF52540 1 237 8.52E-81 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_1514 571129d74cd097e6e11fd8f3432399d3 344 Pfam PF00005 ABC transporter 16 159 3.0E-34 T 30-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CL1_1514 571129d74cd097e6e11fd8f3432399d3 344 Gene3D G3DSA:3.40.50.300 1 234 1.8E-74 T 30-10-2018 CL1_1514 571129d74cd097e6e11fd8f3432399d3 344 TIGRFAM TIGR00638 Mop: molybdenum-pterin binding domain 280 343 1.7E-16 T 30-10-2018 IPR004606 Molybdenum-pterin binding GO:0015689 CL1_1514 571129d74cd097e6e11fd8f3432399d3 344 Pfam PF03459 TOBE domain 281 343 4.4E-15 T 30-10-2018 IPR005116 Transport-associated OB, type 1 CL1_1514 571129d74cd097e6e11fd8f3432399d3 344 SMART SM00382 25 271 2.2E-13 T 30-10-2018 IPR003593 AAA+ ATPase domain CL1_1514 571129d74cd097e6e11fd8f3432399d3 344 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 30-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CL1_0376 e982083a36e29cc4ca643b446b5cc775 428 Pfam PF09706 CRISPR-associated protein (Cas_CXXC_CXXC) 64 125 1.1E-11 T 30-10-2018 IPR019121 CRISPR-associated protein, CXXC-CXXC domain CL1_0376 e982083a36e29cc4ca643b446b5cc775 428 TIGRFAM TIGR01908 cas_CXXC_CXXC: CRISPR-associated protein Cas8b1/Cst1, subtype I-B/TNEAP 63 365 8.3E-86 T 30-10-2018 IPR010180 CRISPR-associated protein, CXXC-CXXC CL1_0757 c67d07598047d4f1daf9f4d47dbbf22d 178 Hamap MF_00209 Inorganic pyrophosphatase [ppa]. 15 171 36.444 T 30-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 CL1_0757 c67d07598047d4f1daf9f4d47dbbf22d 178 ProSitePatterns PS00387 Inorganic pyrophosphatase signature. 66 72 - T 30-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 CL1_0757 c67d07598047d4f1daf9f4d47dbbf22d 178 Pfam PF00719 Inorganic pyrophosphatase 20 171 6.2E-58 T 30-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 CL1_0757 c67d07598047d4f1daf9f4d47dbbf22d 178 SUPERFAMILY SSF50324 2 172 4.06E-67 T 30-10-2018 IPR036649 Inorganic pyrophosphatase superfamily GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 CL1_0757 c67d07598047d4f1daf9f4d47dbbf22d 178 Gene3D G3DSA:3.90.80.10 1 178 7.9E-75 T 30-10-2018 IPR036649 Inorganic pyrophosphatase superfamily GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 CL1_1102 b49940070c08dde08a8f17d3d6462000 142 SUPERFAMILY SSF54690 3 135 1.15E-45 T 30-10-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 CL1_1102 b49940070c08dde08a8f17d3d6462000 142 Gene3D G3DSA:3.90.1170.40 1 136 1.3E-49 T 30-10-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 CL1_1102 b49940070c08dde08a8f17d3d6462000 142 Pfam PF02391 MoaE protein 5 117 6.3E-37 T 30-10-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 CL1_0996 49c4aacf54df464f5f9fdac23f408afb 421 Pfam PF00884 Sulfatase 6 327 1.6E-24 T 30-10-2018 IPR000917 Sulfatase, N-terminal GO:0008484 CL1_0996 49c4aacf54df464f5f9fdac23f408afb 421 SUPERFAMILY SSF53649 5 347 9.65E-39 T 30-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 CL1_2030 efc983a4b68f1958047d8f42f6212495 441 Gene3D G3DSA:3.30.2290.10 1 206 4.9E-21 T 30-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal CL1_2030 efc983a4b68f1958047d8f42f6212495 441 SUPERFAMILY SSF111283 2 439 1.09E-96 T 30-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 CL1_2030 efc983a4b68f1958047d8f42f6212495 441 Pfam PF01523 Putative modulator of DNA gyrase 14 304 2.4E-46 T 30-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 CL1_0798 a3d6001252692a8eeabfbabe2ffa0c11 436 Pfam PF13173 AAA domain 35 165 5.5E-34 T 30-10-2018 CL1_0798 a3d6001252692a8eeabfbabe2ffa0c11 436 SUPERFAMILY SSF52540 23 227 1.65E-19 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_0798 a3d6001252692a8eeabfbabe2ffa0c11 436 Pfam PF13635 Domain of unknown function (DUF4143) 223 373 3.3E-17 T 30-10-2018 IPR025420 Domain of unknown function DUF4143 CL1_0075 24a773795e5ecc65e64a6f6295e63e3e 161 Pfam PF03551 Transcriptional regulator PadR-like family 22 95 6.9E-16 T 30-10-2018 IPR005149 Transcription regulator PadR, N-terminal CL1_0075 24a773795e5ecc65e64a6f6295e63e3e 161 SUPERFAMILY SSF46785 5 101 1.27E-22 T 30-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CL1_0075 24a773795e5ecc65e64a6f6295e63e3e 161 Gene3D G3DSA:1.10.10.10 13 111 2.8E-17 T 30-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CL1_0087 af486dfe66b7fb73788eb35846a1ee94 93 Hamap MF_00634 UPF0235 protein YggU [yggU]. 7 93 21.16 T 30-10-2018 IPR003746 Protein of unknown function DUF167 CL1_0087 af486dfe66b7fb73788eb35846a1ee94 93 Gene3D G3DSA:3.30.1200.10 1 93 3.1E-32 T 30-10-2018 IPR036591 YggU-like superfamily CL1_0087 af486dfe66b7fb73788eb35846a1ee94 93 SMART SM01152 7 82 7.2E-33 T 30-10-2018 IPR003746 Protein of unknown function DUF167 CL1_0087 af486dfe66b7fb73788eb35846a1ee94 93 Pfam PF02594 Uncharacterised ACR, YggU family COG1872 11 80 1.1E-24 T 30-10-2018 IPR003746 Protein of unknown function DUF167 CL1_0087 af486dfe66b7fb73788eb35846a1ee94 93 SUPERFAMILY SSF69786 3 91 8.24E-28 T 30-10-2018 IPR036591 YggU-like superfamily CL1_0087 af486dfe66b7fb73788eb35846a1ee94 93 TIGRFAM TIGR00251 TIGR00251: TIGR00251 family protein 4 82 1.0E-28 T 30-10-2018 IPR005228 Conserved hypothetical protein CHP00251 CL1_1744 7944e2299350101894f3ba0ae8c145a5 174 SMART SM00562 6 146 2.2E-82 T 30-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CL1_1744 7944e2299350101894f3ba0ae8c145a5 174 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 6 144 36.121 T 30-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CL1_1744 7944e2299350101894f3ba0ae8c145a5 174 Pfam PF00334 Nucleoside diphosphate kinase 7 143 3.8E-57 T 30-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CL1_1744 7944e2299350101894f3ba0ae8c145a5 174 ProSitePatterns PS00469 Nucleoside diphosphate kinases active site. 120 128 - T 30-10-2018 IPR023005 Nucleoside diphosphate kinase, active site KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CL1_1744 7944e2299350101894f3ba0ae8c145a5 174 PRINTS PR01243 Nucleoside diphosphate kinase signature 73 90 2.8E-42 T 30-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CL1_1744 7944e2299350101894f3ba0ae8c145a5 174 PRINTS PR01243 Nucleoside diphosphate kinase signature 53 72 2.8E-42 T 30-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CL1_1744 7944e2299350101894f3ba0ae8c145a5 174 PRINTS PR01243 Nucleoside diphosphate kinase signature 94 110 2.8E-42 T 30-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CL1_1744 7944e2299350101894f3ba0ae8c145a5 174 PRINTS PR01243 Nucleoside diphosphate kinase signature 9 31 2.8E-42 T 30-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CL1_1744 7944e2299350101894f3ba0ae8c145a5 174 PRINTS PR01243 Nucleoside diphosphate kinase signature 120 139 2.8E-42 T 30-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CL1_1744 7944e2299350101894f3ba0ae8c145a5 174 Gene3D G3DSA:3.30.70.141 2 159 3.4E-69 T 30-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CL1_1744 7944e2299350101894f3ba0ae8c145a5 174 SUPERFAMILY SSF54919 6 152 2.1E-60 T 30-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CL1_1311 f3777d25a8a6ff65c9149c4cb929f1bc 395 Gene3D G3DSA:3.40.640.10 55 291 5.1E-140 T 30-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 CL1_1311 f3777d25a8a6ff65c9149c4cb929f1bc 395 TIGRFAM TIGR01825 gly_Cac_T_rel: putative pyridoxal phosphate-dependent acyltransferase 7 394 2.5E-201 T 30-10-2018 IPR010962 Putative 8-amino-7-oxononanoate synthase, Archaea/Firmicutes type CL1_1311 f3777d25a8a6ff65c9149c4cb929f1bc 395 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 238 247 - T 30-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 CL1_1311 f3777d25a8a6ff65c9149c4cb929f1bc 395 Gene3D G3DSA:3.90.1150.10 35 385 5.1E-140 T 30-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 CL1_1311 f3777d25a8a6ff65c9149c4cb929f1bc 395 SUPERFAMILY SSF53383 4 391 3.54E-118 T 30-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase CL1_1311 f3777d25a8a6ff65c9149c4cb929f1bc 395 Pfam PF00155 Aminotransferase class I and II 39 383 1.1E-70 T 30-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CL1_1709 d233f9f4f2f401aadab5e0afb3d73105 168 TIGRFAM TIGR00288 TIGR00288: TIGR00288 family protein 22 161 6.8E-64 T 30-10-2018 IPR002790 Conserved hypothetical protein CHP00288 CL1_1709 d233f9f4f2f401aadab5e0afb3d73105 168 ProDom PD010896 FAMILY DUF88 ARCHAEBACTERIAL PROTEIN MJ0482 PH0073 PF2040 VNG1608C MA3857 PF2039 28 101 1.0E-31 T 30-10-2018 CL1_1709 d233f9f4f2f401aadab5e0afb3d73105 168 Gene3D G3DSA:3.40.50.1010 22 162 6.1E-12 T 30-10-2018 CL1_1709 d233f9f4f2f401aadab5e0afb3d73105 168 Pfam PF01936 NYN domain 29 159 3.6E-21 T 30-10-2018 IPR021139 NYN domain, limkain-b1-type CL1_0083 0e47469aa956b6c9630db9d46a539a7d 883 Gene3D G3DSA:3.40.50.880 645 874 5.2E-13 T 30-10-2018 IPR029062 Class I glutamine amidotransferase-like CL1_0083 0e47469aa956b6c9630db9d46a539a7d 883 SUPERFAMILY SSF52317 639 881 7.32E-27 T 30-10-2018 IPR029062 Class I glutamine amidotransferase-like CL1_0083 0e47469aa956b6c9630db9d46a539a7d 883 Gene3D G3DSA:2.60.40.10 378 468 1.6E-6 T 30-10-2018 IPR013783 Immunoglobulin-like fold CL1_0083 0e47469aa956b6c9630db9d46a539a7d 883 ProDom PD117176 AQ_1776 652 772 0.003 T 30-10-2018 CL1_0083 0e47469aa956b6c9630db9d46a539a7d 883 Pfam PF09822 ABC-type uncharacterized transport system 667 758 8.6E-9 T 30-10-2018 IPR019196 ABC-type uncharacterised transport system Reactome: R-HSA-5610787|Reactome: R-HSA-5620924 CL1_1326 3e29ff5e0e102dc320f55c991ef11c73 188 PIRSF PIRSF006503 1 188 6.8E-83 T 30-10-2018 IPR007162 Protein of unknown function DUF366 CL1_1326 3e29ff5e0e102dc320f55c991ef11c73 188 Pfam PF04017 Domain of unknown function (DUF366) 6 185 6.0E-68 T 30-10-2018 IPR007162 Protein of unknown function DUF366 CL1_1326 3e29ff5e0e102dc320f55c991ef11c73 188 ProDom PD022700 PH0223 5/5 GENOME PF0133 SEGMENT UNCHARACTERIZED MA4198 MJ0805 4 186 4.0E-92 T 30-10-2018 IPR007162 Protein of unknown function DUF366 CL1_1326 3e29ff5e0e102dc320f55c991ef11c73 188 Gene3D G3DSA:3.30.930.10 1 188 1.3E-71 T 30-10-2018 CL1_1326 3e29ff5e0e102dc320f55c991ef11c73 188 SUPERFAMILY SSF55681 3 186 1.99E-71 T 30-10-2018 CL1_1904 8bf0a9055d99d39d34d6c2300d81672a 960 Gene3D G3DSA:2.40.128.390 609 676 3.0E-84 T 30-10-2018 CL1_1904 8bf0a9055d99d39d34d6c2300d81672a 960 Gene3D G3DSA:2.60.40.3020 719 959 2.5E-110 T 30-10-2018 CL1_1904 8bf0a9055d99d39d34d6c2300d81672a 960 Gene3D G3DSA:2.60.40.3030 819 951 2.5E-110 T 30-10-2018 CL1_1904 8bf0a9055d99d39d34d6c2300d81672a 960 Gene3D G3DSA:3.40.50.12610 503 717 3.0E-84 T 30-10-2018 CL1_1904 8bf0a9055d99d39d34d6c2300d81672a 960 Pfam PF02516 Oligosaccharyl transferase STT3 subunit 97 531 4.5E-8 T 30-10-2018 IPR003674 Oligosaccharyl transferase, STT3 subunit GO:0004576|GO:0006486|GO:0016020 CL1_0166 19b934f471b4ba636ae24bd087850f24 128 SUPERFAMILY SSF52016 2 126 1.73E-45 T 30-10-2018 CL1_0166 19b934f471b4ba636ae24bd087850f24 128 PIRSF PIRSF004966 1 128 1.1E-55 T 30-10-2018 IPR012016 Aconitase X subunit 2, putative CL1_0166 19b934f471b4ba636ae24bd087850f24 128 Gene3D G3DSA:3.50.30.10 1 128 2.0E-51 T 30-10-2018 CL1_0166 19b934f471b4ba636ae24bd087850f24 128 Pfam PF01989 Protein of unknown function DUF126 22 101 2.8E-36 T 30-10-2018 IPR002840 Aconitase X swivel domain, putative CL1_0166 19b934f471b4ba636ae24bd087850f24 128 Hamap MF_00078 UPF0107 protein . 1 127 32.618 T 30-10-2018 IPR020794 Aconitase X subunit 2, archaeal, putative CL1_0854 dd516cbe5069fba9bcd62788a5de507c 2029 SUPERFAMILY SSF49452 1721 1818 1.22E-5 T 30-10-2018 IPR013784 Carbohydrate-binding-like fold GO:0030246 CL1_0854 dd516cbe5069fba9bcd62788a5de507c 2029 Pfam PF13620 Carboxypeptidase regulatory-like domain 1726 1819 1.7E-7 T 30-10-2018 CL1_0854 dd516cbe5069fba9bcd62788a5de507c 2029 Gene3D G3DSA:2.60.40.1120 1726 1820 5.5E-5 T 30-10-2018 CL1_0902 0106e751f95e964221ea0649c2047078 249 Pfam PF06745 KaiC 10 246 1.6E-78 T 30-10-2018 IPR014774 KaiC-like domain CL1_0902 0106e751f95e964221ea0649c2047078 249 Gene3D G3DSA:3.40.50.300 2 249 4.3E-74 T 30-10-2018 CL1_0902 0106e751f95e964221ea0649c2047078 249 SUPERFAMILY SSF52540 7 244 1.46E-45 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_0289 683b3f90e0c0f6b439a4c34f173ac906 268 Gene3D G3DSA:3.60.15.10 1 268 3.2E-75 T 30-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like CL1_0289 683b3f90e0c0f6b439a4c34f173ac906 268 Pfam PF00753 Metallo-beta-lactamase superfamily 21 188 1.7E-15 T 30-10-2018 IPR001279 Metallo-beta-lactamase CL1_0289 683b3f90e0c0f6b439a4c34f173ac906 268 SMART SM00849 21 239 3.5E-7 T 30-10-2018 IPR001279 Metallo-beta-lactamase CL1_0289 683b3f90e0c0f6b439a4c34f173ac906 268 SUPERFAMILY SSF56281 7 268 2.23E-31 T 30-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like CL1_1180 65b64930e4aeaf2e544294422561c4c2 157 PRINTS PR00728 Eukaryotic signal peptidase (S26B) family signature 38 53 1.2E-8 T 30-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 CL1_1180 65b64930e4aeaf2e544294422561c4c2 157 PRINTS PR00728 Eukaryotic signal peptidase (S26B) family signature 103 114 1.2E-8 T 30-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 CL1_1180 65b64930e4aeaf2e544294422561c4c2 157 Pfam PF00717 Peptidase S24-like 38 88 7.0E-8 T 30-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CL1_1180 65b64930e4aeaf2e544294422561c4c2 157 SUPERFAMILY SSF51306 35 90 1.91E-11 T 30-10-2018 IPR036286 LexA/Signal peptidase-like superfamily CL1_1180 65b64930e4aeaf2e544294422561c4c2 157 TIGRFAM TIGR02228 sigpep_I_arch: signal peptidase I 4 150 3.1E-35 T 30-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 CL1_0664 061315a7716551cee2437f84106c093e 222 Gene3D G3DSA:2.20.25.420 7 69 3.9E-7 T 30-10-2018 CL1_0664 061315a7716551cee2437f84106c093e 222 TIGRFAM TIGR00340 zpr1_rel: zinc finger protein ZPR1 homolog 26 191 1.4E-69 T 30-10-2018 IPR004470 Zinc finger, ZPR1-type, subgroup GO:0008270 CL1_0664 061315a7716551cee2437f84106c093e 222 Pfam PF03367 ZPR1 zinc-finger domain 25 181 4.4E-38 T 30-10-2018 IPR004457 Zinc finger, ZPR1-type GO:0008270 CL1_0664 061315a7716551cee2437f84106c093e 222 TIGRFAM TIGR00310 ZPR1_znf: ZPR1 zinc finger domain 25 204 5.7E-61 T 30-10-2018 IPR004457 Zinc finger, ZPR1-type GO:0008270 CL1_0664 061315a7716551cee2437f84106c093e 222 Gene3D G3DSA:2.60.120.1040 73 198 2.3E-21 T 30-10-2018 CL1_0664 061315a7716551cee2437f84106c093e 222 SMART SM00709 24 184 9.0E-79 T 30-10-2018 IPR004457 Zinc finger, ZPR1-type GO:0008270 CL1_0732 b54bed22193c267b6c80f3cf1f069b9d 442 Gene3D G3DSA:3.40.50.150 149 439 2.1E-87 T 30-10-2018 CL1_0732 b54bed22193c267b6c80f3cf1f069b9d 442 Pfam PF01189 16S rRNA methyltransferase RsmB/F 244 437 6.5E-62 T 30-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 CL1_0732 b54bed22193c267b6c80f3cf1f069b9d 442 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 255 265 2.7E-24 T 30-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase CL1_0732 b54bed22193c267b6c80f3cf1f069b9d 442 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 323 335 2.7E-24 T 30-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase CL1_0732 b54bed22193c267b6c80f3cf1f069b9d 442 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 422 439 2.7E-24 T 30-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase CL1_0732 b54bed22193c267b6c80f3cf1f069b9d 442 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 373 389 2.7E-24 T 30-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase CL1_0732 b54bed22193c267b6c80f3cf1f069b9d 442 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 226 240 2.7E-24 T 30-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase CL1_0732 b54bed22193c267b6c80f3cf1f069b9d 442 Pfam PF17125 N-terminal domain of 16S rRNA methyltransferase RsmF 152 239 1.1E-8 T 30-10-2018 IPR031341 Ribosomal RNA small subunit methyltransferase F, N-terminal Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 CL1_0732 b54bed22193c267b6c80f3cf1f069b9d 442 SUPERFAMILY SSF53335 146 440 4.76E-77 T 30-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CL1_0732 b54bed22193c267b6c80f3cf1f069b9d 442 Gene3D G3DSA:1.10.940.10 2 148 1.2E-39 T 30-10-2018 IPR035926 NusB-like superfamily CL1_1260 cdd0c654a2c6b4db6b223fcf43687bc0 215 SUPERFAMILY SSF109755 19 209 1.48E-7 T 30-10-2018 CL1_1260 cdd0c654a2c6b4db6b223fcf43687bc0 215 Gene3D G3DSA:1.20.58.220 3 212 3.2E-48 T 30-10-2018 IPR038078 PhoU-like domain superfamily CL1_1260 cdd0c654a2c6b4db6b223fcf43687bc0 215 TIGRFAM TIGR00153 TIGR00153: TIGR00153 family protein 16 214 3.5E-40 T 30-10-2018 IPR002727 Protein of unknown function DUF47 CL1_1260 cdd0c654a2c6b4db6b223fcf43687bc0 215 Pfam PF01865 Protein of unknown function DUF47 7 211 5.8E-41 T 30-10-2018 IPR018445 Putative phosphate transport regulator CL1_1546 dcfc91ac7c84d56a00348452fad27a1f 145 Gene3D G3DSA:1.10.10.10 55 127 2.6E-6 T 30-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CL1_1546 dcfc91ac7c84d56a00348452fad27a1f 145 SUPERFAMILY SSF46785 57 129 1.12E-7 T 30-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CL1_0274 3d36dcff5beea53a815b936258727051 348 PIRSF PIRSF004869 1 313 2.0E-95 T 30-10-2018 IPR016431 Pyruvate-formate lyase-activating enzyme, predicted CL1_0274 3d36dcff5beea53a815b936258727051 348 Gene3D G3DSA:3.20.20.70 63 286 2.0E-36 T 30-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CL1_0274 3d36dcff5beea53a815b936258727051 348 SUPERFAMILY SSF102114 58 315 1.73E-34 T 30-10-2018 CL1_0274 3d36dcff5beea53a815b936258727051 348 Pfam PF13353 4Fe-4S single cluster domain 73 166 4.3E-7 T 30-10-2018 CL1_0274 3d36dcff5beea53a815b936258727051 348 Pfam PF04055 Radical SAM superfamily 78 234 1.3E-20 T 30-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CL1_0274 3d36dcff5beea53a815b936258727051 348 TIGRFAM TIGR04337 AmmeMemoSam_rS: AmmeMemoRadiSam system radical SAM enzyme 6 342 2.5E-112 T 30-10-2018 IPR027596 AmmeMemoRadiSam system radical SAM enzyme CL1_0254 2d6d016996c1c6e66e4c3161e0871a96 286 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 24 31 - T 30-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CL1_0254 2d6d016996c1c6e66e4c3161e0871a96 286 SUPERFAMILY SSF53671 9 284 1.44E-109 T 30-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 CL1_0254 2d6d016996c1c6e66e4c3161e0871a96 286 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 9 119 3.1E-44 T 30-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 CL1_0254 2d6d016996c1c6e66e4c3161e0871a96 286 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 2 281 1.4E-138 T 30-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 CL1_0254 2d6d016996c1c6e66e4c3161e0871a96 286 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 1 282 79.538 T 30-10-2018 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 CL1_0254 2d6d016996c1c6e66e4c3161e0871a96 286 Gene3D G3DSA:3.40.50.1370 2 278 2.3E-130 T 30-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 CL1_0254 2d6d016996c1c6e66e4c3161e0871a96 286 PRINTS PR00102 Ornithine carbamoyltransferase signature 55 68 1.2E-30 T 30-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 CL1_0254 2d6d016996c1c6e66e4c3161e0871a96 286 PRINTS PR00102 Ornithine carbamoyltransferase signature 198 208 1.2E-30 T 30-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 CL1_0254 2d6d016996c1c6e66e4c3161e0871a96 286 PRINTS PR00102 Ornithine carbamoyltransferase signature 260 271 1.2E-30 T 30-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 CL1_0254 2d6d016996c1c6e66e4c3161e0871a96 286 PRINTS PR00102 Ornithine carbamoyltransferase signature 22 36 1.2E-30 T 30-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 CL1_0254 2d6d016996c1c6e66e4c3161e0871a96 286 PRINTS PR00102 Ornithine carbamoyltransferase signature 95 109 1.2E-30 T 30-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 CL1_0254 2d6d016996c1c6e66e4c3161e0871a96 286 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 234 243 1.6E-29 T 30-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CL1_0254 2d6d016996c1c6e66e4c3161e0871a96 286 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 106 117 1.6E-29 T 30-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CL1_0254 2d6d016996c1c6e66e4c3161e0871a96 286 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 246 269 1.6E-29 T 30-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CL1_0254 2d6d016996c1c6e66e4c3161e0871a96 286 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 24 43 1.6E-29 T 30-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CL1_0254 2d6d016996c1c6e66e4c3161e0871a96 286 Gene3D G3DSA:3.40.50.1370 109 268 2.3E-130 T 30-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 CL1_0254 2d6d016996c1c6e66e4c3161e0871a96 286 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 125 279 5.7E-66 T 30-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 CL1_1290 e125449be65eceaaeabbf5602575aaa9 192 SUPERFAMILY SSF52540 1 189 2.54E-18 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_1290 e125449be65eceaaeabbf5602575aaa9 192 Pfam PF13238 AAA domain 3 142 2.4E-18 T 30-10-2018 CL1_1290 e125449be65eceaaeabbf5602575aaa9 192 Gene3D G3DSA:3.40.50.300 2 189 2.3E-42 T 30-10-2018 CL1_2004 742c50c1acdb14593e63d3f6eedb2028 319 Gene3D G3DSA:1.10.260.40 126 195 3.8E-12 T 30-10-2018 CL1_2004 742c50c1acdb14593e63d3f6eedb2028 319 SUPERFAMILY SSF47413 127 187 4.35E-13 T 30-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 CL1_2004 742c50c1acdb14593e63d3f6eedb2028 319 Hamap MF_00584 Putative HTH-type transcriptional regulatory protein . 3 301 28.736 T 30-10-2018 IPR020886 Transcription regulator HTH, Cro/C1-type DNA-binding GO:0003700|GO:0006355 CL1_2004 742c50c1acdb14593e63d3f6eedb2028 319 Pfam PF01381 Helix-turn-helix 132 185 3.2E-13 T 30-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CL1_2004 742c50c1acdb14593e63d3f6eedb2028 319 SMART SM00530 131 186 7.8E-13 T 30-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CL1_0290 5b2ba26ea27ed5ecea3abdb58875db98 269 Pfam PF02673 Bacitracin resistance protein BacA 11 255 3.8E-27 T 30-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 CL1_0244 525adad799bd23d2990ca88761a98d63 212 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 146 182 1.5E-6 T 30-10-2018 IPR006847 Translation initiation factor IF-2, N-terminal CL1_0244 525adad799bd23d2990ca88761a98d63 212 Pfam PF14358 Domain of unknown function (DUF4405) 10 73 7.1E-15 T 30-10-2018 IPR025517 Domain of unknown function DUF4405 CL1_0244 525adad799bd23d2990ca88761a98d63 212 SUPERFAMILY SSF46955 149 188 1.19E-5 T 30-10-2018 IPR009061 Putative DNA-binding domain superfamily CL1_1960 471a7883dc0ffe1f8ad02c55f58273a0 89 Gene3D G3DSA:3.30.70.240 1 67 2.9E-26 T 30-10-2018 CL1_1960 471a7883dc0ffe1f8ad02c55f58273a0 89 TIGRFAM TIGR01573 cas2: CRISPR-associated endonuclease Cas2 3 82 1.1E-13 T 30-10-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 CL1_1960 471a7883dc0ffe1f8ad02c55f58273a0 89 SUPERFAMILY SSF143430 4 82 4.19E-25 T 30-10-2018 CL1_1960 471a7883dc0ffe1f8ad02c55f58273a0 89 Hamap MF_01471 CRISPR-associated endoribonuclease Cas2 [cas2]. 3 89 15.133 T 30-10-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 CL1_1960 471a7883dc0ffe1f8ad02c55f58273a0 89 Pfam PF09827 CRISPR associated protein Cas2 4 71 9.7E-21 T 30-10-2018 IPR019199 Virulence-associated protein D / CRISPR associated protein Cas2 CL1_1927 f9842f07b663d8d0460b38693d09db7f 250 SUPERFAMILY SSF52540 2 219 1.57E-46 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_1927 f9842f07b663d8d0460b38693d09db7f 250 Pfam PF00005 ABC transporter 18 155 2.3E-19 T 30-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CL1_1927 f9842f07b663d8d0460b38693d09db7f 250 ProSitePatterns PS00211 ABC transporters family signature. 128 142 - T 30-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CL1_1927 f9842f07b663d8d0460b38693d09db7f 250 SMART SM00382 26 203 3.8E-4 T 30-10-2018 IPR003593 AAA+ ATPase domain CL1_1927 f9842f07b663d8d0460b38693d09db7f 250 Gene3D G3DSA:3.40.50.300 1 235 4.6E-47 T 30-10-2018 CL1_1990 485298e40e3923afbc7c264b4d4967e5 290 Hamap MF_00188 Protease HtpX [htpX]. 6 280 30.023 T 30-10-2018 IPR022919 Peptidase M48, protease HtpX, putative GO:0004222 CL1_1990 485298e40e3923afbc7c264b4d4967e5 290 Pfam PF01435 Peptidase family M48 67 280 3.6E-36 T 30-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 CL1_1990 485298e40e3923afbc7c264b4d4967e5 290 Gene3D G3DSA:3.30.2010.10 61 151 4.0E-32 T 30-10-2018 CL1_1304 56c128c00e908da5ffb62dd8a31433ae 200 ProSitePatterns PS00854 Proteasome beta-type subunits signature. 11 58 - T 30-10-2018 IPR016050 Proteasome beta-type subunit, conserved site GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 CL1_1304 56c128c00e908da5ffb62dd8a31433ae 200 Hamap MF_02113_A Proteasome subunit beta [prcB]. 3 199 34.546 T 30-10-2018 IPR019983 Peptidase T1A, proteasome beta-subunit, archaeal GO:0004175|GO:0005839|GO:0051603 CL1_1304 56c128c00e908da5ffb62dd8a31433ae 200 Pfam PF00227 Proteasome subunit 5 186 3.8E-52 T 30-10-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 CL1_1304 56c128c00e908da5ffb62dd8a31433ae 200 Gene3D G3DSA:3.60.20.10 1 199 1.3E-61 T 30-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CL1_1304 56c128c00e908da5ffb62dd8a31433ae 200 SUPERFAMILY SSF56235 2 193 5.29E-59 T 30-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CL1_1304 56c128c00e908da5ffb62dd8a31433ae 200 TIGRFAM TIGR03634 arc_protsome_B: proteasome endopeptidase complex, archaeal, beta subunit 7 191 1.0E-77 T 30-10-2018 IPR019983 Peptidase T1A, proteasome beta-subunit, archaeal GO:0004175|GO:0005839|GO:0051603 CL1_1304 56c128c00e908da5ffb62dd8a31433ae 200 PRINTS PR00141 Proteasome component signature 135 146 4.8E-5 T 30-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 CL1_1304 56c128c00e908da5ffb62dd8a31433ae 200 PRINTS PR00141 Proteasome component signature 146 157 4.8E-5 T 30-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 CL1_1304 56c128c00e908da5ffb62dd8a31433ae 200 PRINTS PR00141 Proteasome component signature 15 30 4.8E-5 T 30-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 CL1_1354 f2f2c2b40a9d63d8f48050dab9429487 67 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 7 62 1.3E-17 T 30-10-2018 CL1_1354 f2f2c2b40a9d63d8f48050dab9429487 67 SUPERFAMILY SSF54862 3 65 1.43E-14 T 30-10-2018 CL1_1354 f2f2c2b40a9d63d8f48050dab9429487 67 Gene3D G3DSA:3.30.70.20 2 67 4.8E-23 T 30-10-2018 CL1_1354 f2f2c2b40a9d63d8f48050dab9429487 67 PRINTS PR00352 3Fe-4S ferredoxin signature 18 28 2.9E-9 T 30-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 CL1_1354 f2f2c2b40a9d63d8f48050dab9429487 67 PRINTS PR00352 3Fe-4S ferredoxin signature 7 18 2.9E-9 T 30-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 CL1_1354 f2f2c2b40a9d63d8f48050dab9429487 67 PRINTS PR00352 3Fe-4S ferredoxin signature 50 62 2.9E-9 T 30-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 CL1_1493 9e8efe2b456df9e9eed7c176c6581220 97 Pfam PF13412 Winged helix-turn-helix DNA-binding 19 61 3.6E-5 T 30-10-2018 CL1_1493 9e8efe2b456df9e9eed7c176c6581220 97 SUPERFAMILY SSF46785 15 86 6.75E-12 T 30-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CL1_1493 9e8efe2b456df9e9eed7c176c6581220 97 Gene3D G3DSA:1.10.10.10 5 94 2.0E-10 T 30-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CL1_1493 9e8efe2b456df9e9eed7c176c6581220 97 SMART SM00418 9 91 0.0028 T 30-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CL1_0934 ad649ea6cdae7898532d3b8d6b1a67d8 162 Gene3D G3DSA:1.20.120.610 2 158 4.6E-41 T 30-10-2018 CL1_0934 ad649ea6cdae7898532d3b8d6b1a67d8 162 SUPERFAMILY SSF81333 6 70 1.44E-10 T 30-10-2018 IPR035921 F/V-ATP synthase subunit C superfamily CL1_0934 ad649ea6cdae7898532d3b8d6b1a67d8 162 SUPERFAMILY SSF81333 89 156 6.54E-14 T 30-10-2018 IPR035921 F/V-ATP synthase subunit C superfamily CL1_0934 ad649ea6cdae7898532d3b8d6b1a67d8 162 Pfam PF00137 ATP synthase subunit C 9 68 5.9E-13 T 30-10-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 CL1_0934 ad649ea6cdae7898532d3b8d6b1a67d8 162 Pfam PF00137 ATP synthase subunit C 97 155 8.8E-16 T 30-10-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 CL1_1245 3ff71645b3274d91767461bd32f14e3a 105 Pfam PF14697 4Fe-4S dicluster domain 48 100 5.3E-11 T 30-10-2018 CL1_1245 3ff71645b3274d91767461bd32f14e3a 105 Gene3D G3DSA:3.30.70.20 7 105 3.0E-15 T 30-10-2018 CL1_1245 3ff71645b3274d91767461bd32f14e3a 105 SUPERFAMILY SSF54862 30 103 2.27E-23 T 30-10-2018 CL1_1245 3ff71645b3274d91767461bd32f14e3a 105 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 83 94 - T 30-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CL1_1245 3ff71645b3274d91767461bd32f14e3a 105 TIGRFAM TIGR02179 PorD_KorD: 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate family 29 104 3.5E-33 T 30-10-2018 IPR011898 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate GO:0016625|GO:0051539 CL1_1488 339f0d0dc7dea395cdc3519ad7e4106f 193 ProSitePatterns PS00603 Thymidine kinase cellular-type signature. 177 190 - T 30-10-2018 IPR020633 Thymidine kinase, conserved site GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 CL1_1488 339f0d0dc7dea395cdc3519ad7e4106f 193 Pfam PF00265 Thymidine kinase 7 190 5.9E-53 T 30-10-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 CL1_1488 339f0d0dc7dea395cdc3519ad7e4106f 193 SUPERFAMILY SSF52540 6 144 4.35E-40 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_1488 339f0d0dc7dea395cdc3519ad7e4106f 193 Gene3D G3DSA:3.40.50.300 1 144 4.8E-47 T 30-10-2018 CL1_1488 339f0d0dc7dea395cdc3519ad7e4106f 193 PIRSF PIRSF035805 4 193 1.1E-65 T 30-10-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 CL1_1488 339f0d0dc7dea395cdc3519ad7e4106f 193 Hamap MF_00124 Thymidine kinase [tdk]. 5 193 36.097 T 30-10-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 CL1_1488 339f0d0dc7dea395cdc3519ad7e4106f 193 Gene3D G3DSA:3.30.60.20 145 193 5.3E-24 T 30-10-2018 CL1_1488 339f0d0dc7dea395cdc3519ad7e4106f 193 SUPERFAMILY SSF57716 145 192 7.13E-16 T 30-10-2018 CL1_0331 ddb6e38cdf5ecec365b386ba13878024 322 Pfam PF00288 GHMP kinases N terminal domain 76 136 2.2E-7 T 30-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 CL1_0331 ddb6e38cdf5ecec365b386ba13878024 322 PIRSF PIRSF004884 1 309 4.0E-99 T 30-10-2018 IPR004422 GHMP kinase group 1 KEGG: 00790+2.4.2.54|MetaCyc: PWY-6148 CL1_0331 ddb6e38cdf5ecec365b386ba13878024 322 SUPERFAMILY SSF54211 2 149 1.06E-17 T 30-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CL1_0331 ddb6e38cdf5ecec365b386ba13878024 322 TIGRFAM TIGR00144 beta_RFAP_syn: beta-ribofuranosylaminobenzene 5'-phosphate synthase family 2 307 7.5E-49 T 30-10-2018 IPR004422 GHMP kinase group 1 KEGG: 00790+2.4.2.54|MetaCyc: PWY-6148 CL1_0331 ddb6e38cdf5ecec365b386ba13878024 322 Gene3D G3DSA:3.30.230.10 16 141 3.2E-9 T 30-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CL1_0671 63010a8835a21db65c1f73ccc7ff0d38 260 Pfam PF00227 Proteasome subunit 33 215 1.5E-64 T 30-10-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 CL1_0671 63010a8835a21db65c1f73ccc7ff0d38 260 Gene3D G3DSA:3.60.20.10 5 253 3.2E-91 T 30-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CL1_0671 63010a8835a21db65c1f73ccc7ff0d38 260 Pfam PF10584 Proteasome subunit A N-terminal signature 10 32 4.0E-12 T 30-10-2018 IPR000426 Proteasome alpha-subunit, N-terminal domain GO:0004175|GO:0006511|GO:0019773 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 CL1_0671 63010a8835a21db65c1f73ccc7ff0d38 260 Hamap MF_00289_A Proteasome subunit alpha [prcA]. 5 234 47.624 T 30-10-2018 IPR019982 Proteasome alpha subunit, archaeal GO:0004298|GO:0005839|GO:0051603 CL1_0671 63010a8835a21db65c1f73ccc7ff0d38 260 ProSitePatterns PS00388 Proteasome alpha-type subunits signature. 10 32 - T 30-10-2018 IPR000426 Proteasome alpha-subunit, N-terminal domain GO:0004175|GO:0006511|GO:0019773 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 CL1_0671 63010a8835a21db65c1f73ccc7ff0d38 260 SUPERFAMILY SSF56235 7 242 3.46E-82 T 30-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CL1_0671 63010a8835a21db65c1f73ccc7ff0d38 260 SMART SM00948 10 32 3.4E-10 T 30-10-2018 IPR000426 Proteasome alpha-subunit, N-terminal domain GO:0004175|GO:0006511|GO:0019773 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 CL1_0671 63010a8835a21db65c1f73ccc7ff0d38 260 TIGRFAM TIGR03633 arc_protsome_A: proteasome endopeptidase complex, archaeal, alpha subunit 8 234 1.6E-106 T 30-10-2018 IPR019982 Proteasome alpha subunit, archaeal GO:0004298|GO:0005839|GO:0051603 CL1_1273 946a808f3d2057ed27c5a472e8a87f91 432 Pfam PF01523 Putative modulator of DNA gyrase 18 307 6.6E-50 T 30-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 CL1_1273 946a808f3d2057ed27c5a472e8a87f91 432 SUPERFAMILY SSF111283 5 426 1.7E-84 T 30-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 CL1_1273 946a808f3d2057ed27c5a472e8a87f91 432 Gene3D G3DSA:3.30.2290.10 11 212 2.6E-18 T 30-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal CL1_0366 27d98ed047847c270f8efbb29a954781 241 SUPERFAMILY SSF52768 56 225 1.98E-24 T 30-10-2018 IPR023696 Ureohydrolase domain superfamily CL1_0366 27d98ed047847c270f8efbb29a954781 241 Pfam PF00491 Arginase family 56 223 1.2E-16 T 30-10-2018 IPR006035 Ureohydrolase GO:0046872 CL1_0366 27d98ed047847c270f8efbb29a954781 241 Gene3D G3DSA:3.40.800.10 34 240 2.8E-17 T 30-10-2018 CL1_0366 27d98ed047847c270f8efbb29a954781 241 PIRSF PIRSF036979 29 227 1.8E-13 T 30-10-2018 IPR006035 Ureohydrolase GO:0046872 CL1_0102 bb9b6f9af3920750888897c964093053 345 TIGRFAM TIGR00111 pelota: mRNA surveillance protein pelota 5 344 1.2E-110 T 30-10-2018 IPR004405 Translation release factor pelota GO:0070481|GO:0070966|GO:0071025 CL1_0102 bb9b6f9af3920750888897c964093053 345 SUPERFAMILY SSF53137 119 247 5.23E-31 T 30-10-2018 CL1_0102 bb9b6f9af3920750888897c964093053 345 SMART SM01194 1 117 1.8E-40 T 30-10-2018 IPR005140 eRF1 domain 1/Pelota-like CL1_0102 bb9b6f9af3920750888897c964093053 345 Gene3D G3DSA:3.30.420.60 121 245 1.1E-35 T 30-10-2018 CL1_0102 bb9b6f9af3920750888897c964093053 345 Pfam PF03463 eRF1 domain 1 1 115 1.8E-27 T 30-10-2018 IPR005140 eRF1 domain 1/Pelota-like CL1_0102 bb9b6f9af3920750888897c964093053 345 Pfam PF03464 eRF1 domain 2 124 236 4.1E-16 T 30-10-2018 IPR005141 eRF1 domain 2 CL1_0102 bb9b6f9af3920750888897c964093053 345 Pfam PF03465 eRF1 domain 3 249 344 1.4E-25 T 30-10-2018 IPR005142 eRF1 domain 3 CL1_0102 bb9b6f9af3920750888897c964093053 345 Hamap MF_01853 Protein pelota homolog [pelA]. 1 344 35.034 T 30-10-2018 IPR023521 Translation release factor pelota, archaea GO:0070481|GO:0070966|GO:0071025 CL1_0102 bb9b6f9af3920750888897c964093053 345 Gene3D G3DSA:2.30.30.870 1 118 2.1E-35 T 30-10-2018 IPR038069 Pelota/DOM34, N-terminal domain CL1_0102 bb9b6f9af3920750888897c964093053 345 Gene3D G3DSA:3.30.1330.30 246 345 3.1E-33 T 30-10-2018 IPR029064 50S ribosomal protein L30e-like CL1_0102 bb9b6f9af3920750888897c964093053 345 SUPERFAMILY SSF159065 1 117 2.88E-33 T 30-10-2018 IPR038069 Pelota/DOM34, N-terminal domain CL1_0102 bb9b6f9af3920750888897c964093053 345 SUPERFAMILY SSF55315 239 344 1.0E-29 T 30-10-2018 IPR029064 50S ribosomal protein L30e-like CL1_1099 093a2abd7d8a8042d194cfe24c9978ba 88 Gene3D G3DSA:3.10.20.30 1 88 2.6E-30 T 30-10-2018 IPR012675 Beta-grasp domain superfamily CL1_1099 093a2abd7d8a8042d194cfe24c9978ba 88 TIGRFAM TIGR01687 moaD_arch: MoaD family protein 3 88 3.8E-29 T 30-10-2018 IPR010038 MoaD, archaeal-type CL1_1099 093a2abd7d8a8042d194cfe24c9978ba 88 SUPERFAMILY SSF54285 1 86 2.62E-25 T 30-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp CL1_1099 093a2abd7d8a8042d194cfe24c9978ba 88 TIGRFAM TIGR01682 moaD: molybdopterin converting factor, subunit 1 3 88 7.0E-19 T 30-10-2018 CL1_1099 093a2abd7d8a8042d194cfe24c9978ba 88 Pfam PF02597 ThiS family 5 88 8.3E-24 T 30-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 CL1_0806 b3a08563c098e3e4b3ba250c41ba455a 89 Pfam PF01402 Ribbon-helix-helix protein, copG family 7 44 1.8E-6 T 30-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 CL1_0806 b3a08563c098e3e4b3ba250c41ba455a 89 Gene3D G3DSA:1.10.1220.10 11 47 1.9E-8 T 30-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CL1_0806 b3a08563c098e3e4b3ba250c41ba455a 89 SUPERFAMILY SSF47598 4 49 2.52E-10 T 30-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 CL1_0378 1af57cc67492ee498e79ec88ccc6c4ea 205 TIGRFAM TIGR01895 cas_Cas5t: CRISPR-associated protein Cas5, subtype I-B/TNEAP 1 193 1.0E-57 T 30-10-2018 IPR013337 CRISPR-associated protein Cas5, Tneap type CL1_0378 1af57cc67492ee498e79ec88ccc6c4ea 205 TIGRFAM TIGR02593 CRISPR_cas5: CRISPR-associated protein Cas5 1 43 2.7E-18 T 30-10-2018 IPR013422 CRISPR-associated protein Cas5, N-terminal CL1_0378 1af57cc67492ee498e79ec88ccc6c4ea 205 Pfam PF09704 CRISPR-associated protein (Cas_Cas5) 2 136 1.0E-6 T 30-10-2018 IPR021124 CRISPR-associated protein, Cas5 GO:0043571 CL1_1295 a65f0446d0f744a405b61ebe259d1aab 298 SMART SM00530 19 75 0.0023 T 30-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CL1_1295 a65f0446d0f744a405b61ebe259d1aab 298 SUPERFAMILY SSF47413 13 69 3.87E-7 T 30-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 CL1_1295 a65f0446d0f744a405b61ebe259d1aab 298 Pfam PF10120 Thiamine-phosphate synthase 133 290 5.4E-43 T 30-10-2018 IPR019293 Thiamine-phosphate synthase ThiN GO:0004789 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CL1_1295 a65f0446d0f744a405b61ebe259d1aab 298 Gene3D G3DSA:3.40.225.10 121 297 3.3E-42 T 30-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily CL1_1295 a65f0446d0f744a405b61ebe259d1aab 298 SUPERFAMILY SSF53639 126 292 1.73E-44 T 30-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily CL1_1815 8fe40ab9c92d883fc2b0af321debc996 227 TIGRFAM TIGR02593 CRISPR_cas5: CRISPR-associated protein Cas5 4 45 1.3E-12 T 30-10-2018 IPR013422 CRISPR-associated protein Cas5, N-terminal CL1_1815 8fe40ab9c92d883fc2b0af321debc996 227 Gene3D G3DSA:3.30.70.2660 21 201 1.8E-9 T 30-10-2018 CL1_1815 8fe40ab9c92d883fc2b0af321debc996 227 Pfam PF09704 CRISPR-associated protein (Cas_Cas5) 25 187 5.1E-11 T 30-10-2018 IPR021124 CRISPR-associated protein, Cas5 GO:0043571 CL1_1411 add6cf2dbcfa4cfcce43ea98ab562679 187 Gene3D G3DSA:3.30.310.10 13 95 1.1E-32 T 30-10-2018 IPR012295 TBP domain superfamily CL1_1411 add6cf2dbcfa4cfcce43ea98ab562679 187 SUPERFAMILY SSF55945 3 91 3.93E-29 T 30-10-2018 CL1_1411 add6cf2dbcfa4cfcce43ea98ab562679 187 SUPERFAMILY SSF55945 94 179 2.98E-30 T 30-10-2018 CL1_1411 add6cf2dbcfa4cfcce43ea98ab562679 187 PRINTS PR00686 Transcription initiation factor TFIID signature 32 51 1.1E-43 T 30-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 CL1_1411 add6cf2dbcfa4cfcce43ea98ab562679 187 PRINTS PR00686 Transcription initiation factor TFIID signature 122 137 1.1E-43 T 30-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 CL1_1411 add6cf2dbcfa4cfcce43ea98ab562679 187 PRINTS PR00686 Transcription initiation factor TFIID signature 8 23 1.1E-43 T 30-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 CL1_1411 add6cf2dbcfa4cfcce43ea98ab562679 187 PRINTS PR00686 Transcription initiation factor TFIID signature 99 115 1.1E-43 T 30-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 CL1_1411 add6cf2dbcfa4cfcce43ea98ab562679 187 PRINTS PR00686 Transcription initiation factor TFIID signature 141 157 1.1E-43 T 30-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 CL1_1411 add6cf2dbcfa4cfcce43ea98ab562679 187 PRINTS PR00686 Transcription initiation factor TFIID signature 51 69 1.1E-43 T 30-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 CL1_1411 add6cf2dbcfa4cfcce43ea98ab562679 187 Pfam PF00352 Transcription factor TFIID (or TATA-binding protein, TBP) 97 178 1.3E-28 T 30-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 CL1_1411 add6cf2dbcfa4cfcce43ea98ab562679 187 Pfam PF00352 Transcription factor TFIID (or TATA-binding protein, TBP) 6 86 8.0E-28 T 30-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 CL1_1411 add6cf2dbcfa4cfcce43ea98ab562679 187 ProSitePatterns PS00351 Transcription factor TFIID repeat signature. 126 175 - T 30-10-2018 IPR030491 TATA-box binding protein, conserved site CL1_1411 add6cf2dbcfa4cfcce43ea98ab562679 187 Hamap MF_00408 TATA-box-binding protein [tbp]. 2 181 37.628 T 30-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 CL1_1411 add6cf2dbcfa4cfcce43ea98ab562679 187 Gene3D G3DSA:3.30.310.10 96 179 4.5E-35 T 30-10-2018 IPR012295 TBP domain superfamily CL1_1370 78a4b14b2e73f5a26b6c63eb54a876eb 150 SMART SM00670 1 136 0.0048 T 30-10-2018 IPR002716 PIN domain CL1_1370 78a4b14b2e73f5a26b6c63eb54a876eb 150 SUPERFAMILY SSF88723 1 138 2.89E-13 T 30-10-2018 IPR029060 PIN-like domain superfamily CL1_1370 78a4b14b2e73f5a26b6c63eb54a876eb 150 Pfam PF01850 PIN domain 1 136 1.4E-14 T 30-10-2018 IPR002716 PIN domain CL1_1370 78a4b14b2e73f5a26b6c63eb54a876eb 150 Gene3D G3DSA:3.40.50.1010 1 148 6.5E-9 T 30-10-2018 CL1_0032 18a17b0948554b9b9703f432d0f525b6 226 Pfam PF07786 Protein of unknown function (DUF1624) 1 208 1.1E-54 T 30-10-2018 IPR012429 Domain of unknown function DUF1624 Reactome: R-HSA-2024096|Reactome: R-HSA-2206291|Reactome: R-HSA-6798695 CL1_1121 bcb73848e2b8ee95bb7a1bfde29e98d0 199 Gene3D G3DSA:1.10.1760.20 32 194 1.0E-46 T 30-10-2018 CL1_1121 bcb73848e2b8ee95bb7a1bfde29e98d0 199 Pfam PF07155 ECF-type riboflavin transporter, S component 39 190 1.4E-37 T 30-10-2018 IPR009825 ECF transporter, substrate-specific component-like GO:0016020 CL1_0380 8d84c1217d9d32946e5771f3b0a30533 190 Gene3D G3DSA:3.90.320.10 24 190 7.6E-9 T 30-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal CL1_0380 8d84c1217d9d32946e5771f3b0a30533 190 TIGRFAM TIGR00372 cas4: CRISPR-associated protein Cas4 32 189 1.4E-23 T 30-10-2018 IPR013343 CRISPR-associated protein Cas4 CL1_0380 8d84c1217d9d32946e5771f3b0a30533 190 Pfam PF01930 Domain of unknown function DUF83 33 190 1.1E-53 T 30-10-2018 IPR022765 Dna2/Cas4, domain of unknown function DUF83 CL1_1462 88a9c52dd6b5e3882a15d6255f3947f1 401 Gene3D G3DSA:1.20.1250.20 1 184 1.4E-14 T 30-10-2018 CL1_1462 88a9c52dd6b5e3882a15d6255f3947f1 401 Gene3D G3DSA:1.20.1250.20 194 391 3.3E-6 T 30-10-2018 CL1_1462 88a9c52dd6b5e3882a15d6255f3947f1 401 SUPERFAMILY SSF103473 3 391 1.11E-34 T 30-10-2018 IPR036259 MFS transporter superfamily CL1_1462 88a9c52dd6b5e3882a15d6255f3947f1 401 Pfam PF07690 Major Facilitator Superfamily 20 355 9.5E-20 T 30-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CL1_0200 ec08b37c3f0988ba42f3aba842ea6aed 192 Gene3D G3DSA:3.30.460.80 3 148 5.4E-28 T 30-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CL1_0200 ec08b37c3f0988ba42f3aba842ea6aed 192 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 104 145 3.0E-15 T 30-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CL1_0200 ec08b37c3f0988ba42f3aba842ea6aed 192 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 54 171 1.3E-31 T 30-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CL1_0200 ec08b37c3f0988ba42f3aba842ea6aed 192 SUPERFAMILY SSF143243 45 178 3.01E-36 T 30-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CL1_0707 a972a64e24e38b5e97561d57894df957 347 Gene3D G3DSA:3.60.70.12 1 346 5.0E-133 T 30-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CL1_0707 a972a64e24e38b5e97561d57894df957 347 Pfam PF03576 Peptidase family S58 19 324 5.7E-108 T 30-10-2018 IPR005321 Peptidase S58, DmpA CL1_0707 a972a64e24e38b5e97561d57894df957 347 SUPERFAMILY SSF56266 2 344 7.59E-99 T 30-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CL1_0089 e7ff86724a618835e4aff1806d3cca4c 162 SUPERFAMILY SSF159234 2 162 2.35E-37 T 30-10-2018 IPR035930 FomD-like superfamily CL1_0089 e7ff86724a618835e4aff1806d3cca4c 162 Gene3D G3DSA:2.40.380.10 26 162 6.1E-15 T 30-10-2018 IPR035930 FomD-like superfamily CL1_0089 e7ff86724a618835e4aff1806d3cca4c 162 Pfam PF04167 Protein of unknown function (DUF402) 55 121 4.7E-15 T 30-10-2018 IPR007295 Domain of unknown function DUF402 CL1_0205 116f5e629aa3f5c28a5236d728aae759 447 Gene3D G3DSA:3.90.1150.10 9 424 1.2E-145 T 30-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 CL1_0205 116f5e629aa3f5c28a5236d728aae759 447 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 245 282 - T 30-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CL1_0205 116f5e629aa3f5c28a5236d728aae759 447 Gene3D G3DSA:3.40.640.10 63 328 1.2E-145 T 30-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 CL1_0205 116f5e629aa3f5c28a5236d728aae759 447 Pfam PF00202 Aminotransferase class-III 26 428 5.0E-111 T 30-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CL1_0205 116f5e629aa3f5c28a5236d728aae759 447 SUPERFAMILY SSF53383 24 430 1.2E-126 T 30-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase CL1_0205 116f5e629aa3f5c28a5236d728aae759 447 PIRSF PIRSF000521 32 133 1.1E-6 T 30-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CL1_0205 116f5e629aa3f5c28a5236d728aae759 447 PIRSF PIRSF000521 126 431 3.0E-32 T 30-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CL1_0778 88e1e9a5f3bb7c47a190f231718d4b26 69 Pfam PF01954 Protein of unknown function DUF104 1 55 4.6E-19 T 30-10-2018 IPR008203 Uncharacterised protein family UPF0165 CL1_0778 88e1e9a5f3bb7c47a190f231718d4b26 69 Gene3D G3DSA:4.10.1150.10 1 65 2.3E-14 T 30-10-2018 IPR024069 AF2212-like domain superfamily CL1_0778 88e1e9a5f3bb7c47a190f231718d4b26 69 SUPERFAMILY SSF141694 1 56 2.46E-14 T 30-10-2018 CL1_1559 115372f83e9c7c7dcc85635ac6efe28b 146 SUPERFAMILY SSF88723 20 61 4.71E-5 T 30-10-2018 IPR029060 PIN-like domain superfamily CL1_1559 115372f83e9c7c7dcc85635ac6efe28b 146 Pfam PF01927 Mut7-C RNAse domain 1 139 2.6E-41 T 30-10-2018 IPR002782 Mut7-C RNAse domain CL1_0101 e5578e013b38205269d70f88c2ecaf5b 348 SUPERFAMILY SSF55920 123 347 4.19E-85 T 30-10-2018 IPR036005 Creatinase/aminopeptidase-like CL1_0101 e5578e013b38205269d70f88c2ecaf5b 348 Gene3D G3DSA:3.40.350.10 1 122 9.5E-30 T 30-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal CL1_0101 e5578e013b38205269d70f88c2ecaf5b 348 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 280 292 - T 30-10-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site CL1_0101 e5578e013b38205269d70f88c2ecaf5b 348 PRINTS PR00599 Methionine aminopeptidase-1 signature 204 220 6.5E-5 T 30-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CL1_0101 e5578e013b38205269d70f88c2ecaf5b 348 PRINTS PR00599 Methionine aminopeptidase-1 signature 302 314 6.5E-5 T 30-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CL1_0101 e5578e013b38205269d70f88c2ecaf5b 348 SUPERFAMILY SSF53092 6 124 1.67E-25 T 30-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal CL1_0101 e5578e013b38205269d70f88c2ecaf5b 348 Pfam PF00557 Metallopeptidase family M24 133 334 1.0E-70 T 30-10-2018 IPR000994 Peptidase M24 CL1_0101 e5578e013b38205269d70f88c2ecaf5b 348 Gene3D G3DSA:3.90.230.10 123 348 2.4E-90 T 30-10-2018 CL1_0101 e5578e013b38205269d70f88c2ecaf5b 348 Pfam PF01321 Creatinase/Prolidase N-terminal domain 2 124 3.8E-23 T 30-10-2018 IPR000587 Creatinase, N-terminal GO:0016787 CL1_0602 4001a263628b6852dfa897109019bc35 175 SMART SM01415 10 174 2.3E-15 T 30-10-2018 IPR002809 Integral membrane protein EMC3/TMCO1-like GO:0016020 CL1_0602 4001a263628b6852dfa897109019bc35 175 Pfam PF01956 Integral membrane protein DUF106 11 173 7.7E-27 T 30-10-2018 IPR002809 Integral membrane protein EMC3/TMCO1-like GO:0016020 CL1_0735 aa992715dd16b9ba0c3ff2391b1f6d66 344 TIGRFAM TIGR03682 arCOG04112: diphthamide biosynthesis enzyme Dph2 17 324 1.7E-111 T 30-10-2018 IPR022428 Diphthamide synthesis Dph2, archaea GO:0017183 MetaCyc: PWY-6482|MetaCyc: PWY-7546 CL1_0735 aa992715dd16b9ba0c3ff2391b1f6d66 344 Gene3D G3DSA:3.40.50.11860 212 313 2.4E-33 T 30-10-2018 CL1_0735 aa992715dd16b9ba0c3ff2391b1f6d66 344 Gene3D G3DSA:3.40.50.11850 100 208 2.4E-39 T 30-10-2018 CL1_0735 aa992715dd16b9ba0c3ff2391b1f6d66 344 Gene3D G3DSA:3.40.50.11840 6 98 1.0E-32 T 30-10-2018 CL1_0735 aa992715dd16b9ba0c3ff2391b1f6d66 344 Pfam PF01866 Putative diphthamide synthesis protein 25 317 3.6E-76 T 30-10-2018 IPR016435 Diphthamide synthesis DPH1/DPH2 MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 CL1_0735 aa992715dd16b9ba0c3ff2391b1f6d66 344 PIRSF PIRSF004967 1 335 4.5E-83 T 30-10-2018 IPR035435 Diphthamide synthesis DHP1/DPH2, eukaryotes and archaea GO:0017183 MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 CL1_0735 aa992715dd16b9ba0c3ff2391b1f6d66 344 TIGRFAM TIGR00322 diphth2_R: diphthamide biosynthesis enzyme Dph1/Dph2 domain 6 313 8.4E-91 T 30-10-2018 IPR016435 Diphthamide synthesis DPH1/DPH2 MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 CL1_2011 04040ac5041def3d6bca6cd48b8693ea 171 Pfam PF00994 Probable molybdopterin binding domain 17 159 3.3E-35 T 30-10-2018 IPR001453 MoaB/Mog domain CL1_2011 04040ac5041def3d6bca6cd48b8693ea 171 Gene3D G3DSA:3.40.980.10 12 170 3.4E-47 T 30-10-2018 IPR036425 MoaB/Mog-like domain superfamily CL1_2011 04040ac5041def3d6bca6cd48b8693ea 171 SMART SM00852 17 165 1.0E-28 T 30-10-2018 IPR001453 MoaB/Mog domain CL1_2011 04040ac5041def3d6bca6cd48b8693ea 171 SUPERFAMILY SSF53218 13 168 2.88E-44 T 30-10-2018 IPR036425 MoaB/Mog-like domain superfamily CL1_2011 04040ac5041def3d6bca6cd48b8693ea 171 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 14 159 2.2E-35 T 30-10-2018 IPR001453 MoaB/Mog domain CL1_2011 04040ac5041def3d6bca6cd48b8693ea 171 PIRSF PIRSF006443 1 171 2.2E-58 T 30-10-2018 IPR012245 Molybdenum cofactor biosynthesis protein MoaB GO:0006777 CL1_1363 433ecdbd0c5f23baee9fe59325b98810 264 Gene3D G3DSA:3.30.950.10 115 264 3.3E-53 T 30-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 CL1_1363 433ecdbd0c5f23baee9fe59325b98810 264 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 3 211 4.1E-22 T 30-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 CL1_1363 433ecdbd0c5f23baee9fe59325b98810 264 Gene3D G3DSA:3.40.1010.10 1 114 1.6E-40 T 30-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 CL1_1363 433ecdbd0c5f23baee9fe59325b98810 264 TIGRFAM TIGR00522 dph5: diphthine synthase 3 256 8.4E-102 T 30-10-2018 IPR004551 Diphthine synthase GO:0004164|GO:0017183 Reactome: R-HSA-5358493 CL1_1363 433ecdbd0c5f23baee9fe59325b98810 264 SUPERFAMILY SSF53790 1 261 5.5E-62 T 30-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 CL1_1363 433ecdbd0c5f23baee9fe59325b98810 264 PIRSF PIRSF036432 2 260 6.5E-98 T 30-10-2018 IPR004551 Diphthine synthase GO:0004164|GO:0017183 Reactome: R-HSA-5358493 CL1_1363 433ecdbd0c5f23baee9fe59325b98810 264 Hamap MF_01084 Diphthine synthase [dphB]. 2 256 36.14 T 30-10-2018 IPR004551 Diphthine synthase GO:0004164|GO:0017183 Reactome: R-HSA-5358493 CL1_1910 7ecb5cfe60af611030a837c437bd519c 232 Gene3D G3DSA:3.30.420.10 4 163 3.7E-58 T 30-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 CL1_1910 7ecb5cfe60af611030a837c437bd519c 232 Hamap MF_00052_A Ribonuclease HII [rnhB]. 4 208 37.826 T 30-10-2018 IPR020787 Ribonuclease HII, archaea GO:0004523|GO:0005737|GO:0006401|GO:0030145 CL1_1910 7ecb5cfe60af611030a837c437bd519c 232 Gene3D G3DSA:1.10.10.460 164 210 7.2E-26 T 30-10-2018 IPR023160 Ribonuclease HII, helix-loop-helix cap domain superfamily GO:0004523 CL1_1910 7ecb5cfe60af611030a837c437bd519c 232 TIGRFAM TIGR00729 TIGR00729: ribonuclease HII 6 207 2.9E-76 T 30-10-2018 IPR004649 Ribonuclease H2, subunit A GO:0004523|GO:0016070 CL1_1910 7ecb5cfe60af611030a837c437bd519c 232 Pfam PF01351 Ribonuclease HII 6 202 4.7E-51 T 30-10-2018 IPR024567 Ribonuclease HII/HIII domain CL1_1910 7ecb5cfe60af611030a837c437bd519c 232 SUPERFAMILY SSF53098 5 210 4.4E-60 T 30-10-2018 IPR012337 Ribonuclease H-like superfamily CL1_0701 40dc2c2702a0d1de94b032fd6df18a2a 150 SUPERFAMILY SSF88723 1 137 4.32E-14 T 30-10-2018 IPR029060 PIN-like domain superfamily CL1_0701 40dc2c2702a0d1de94b032fd6df18a2a 150 Pfam PF01850 PIN domain 1 136 2.1E-16 T 30-10-2018 IPR002716 PIN domain CL1_0701 40dc2c2702a0d1de94b032fd6df18a2a 150 Gene3D G3DSA:3.40.50.1010 1 138 5.9E-11 T 30-10-2018 CL1_1376 a96b1861cce0e82ee24b06b72022285b 169 Gene3D G3DSA:1.10.10.970 1 64 5.7E-19 T 30-10-2018 CL1_1376 a96b1861cce0e82ee24b06b72022285b 169 Pfam PF01885 RNA 2'-phosphotransferase, Tpt1 / KptA family 1 156 9.3E-31 T 30-10-2018 IPR002745 Phosphotransferase KptA/Tpt1 GO:0006388|GO:0016772 CL1_1376 a96b1861cce0e82ee24b06b72022285b 169 Gene3D G3DSA:3.20.170.30 84 169 1.2E-30 T 30-10-2018 CL1_1376 a96b1861cce0e82ee24b06b72022285b 169 Hamap MF_00299 Probable RNA 2'-phosphotransferase [kptA]. 1 165 29.604 T 30-10-2018 IPR022928 RNA 2'-phosphotransferase KptA, putative GO:0016773 CL1_1376 a96b1861cce0e82ee24b06b72022285b 169 SUPERFAMILY SSF56399 1 167 1.37E-53 T 30-10-2018 CL1_1346 7a202173d1a7475f5eeba1e04264e760 121 SUPERFAMILY SSF46785 17 117 5.46E-16 T 30-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CL1_1346 7a202173d1a7475f5eeba1e04264e760 121 Pfam PF03965 Penicillinase repressor 19 111 5.6E-16 T 30-10-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 CL1_1346 7a202173d1a7475f5eeba1e04264e760 121 Gene3D G3DSA:1.10.10.10 19 86 1.0E-13 T 30-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CL1_0551 1a4be9d84e21ae8bc1c2de46a29c650c 334 Pfam PF04087 Domain of unknown function (DUF389) 146 285 1.2E-26 T 30-10-2018 IPR005240 Protein of unknown function DUF389 CL1_0551 1a4be9d84e21ae8bc1c2de46a29c650c 334 TIGRFAM TIGR00341 TIGR00341: TIGR00341 family protein 102 331 2.4E-40 T 30-10-2018 CL1_1152 4e090583b511e42fd38fbedeae6ff025 69 Gene3D G3DSA:2.40.50.140 5 69 3.6E-26 T 30-10-2018 CL1_1152 4e090583b511e42fd38fbedeae6ff025 69 SUPERFAMILY SSF50249 10 69 1.37E-16 T 30-10-2018 IPR012340 Nucleic acid-binding, OB-fold CL1_1152 4e090583b511e42fd38fbedeae6ff025 69 Pfam PF01938 TRAM domain 13 69 5.2E-15 T 30-10-2018 IPR002792 TRAM domain CL1_0753 66661dbb46888e0a49523c343e9f0a61 169 Pfam PF06510 Protein of unknown function (DUF1102) 46 168 2.8E-31 T 30-10-2018 IPR009482 Protein of unknown function DUF1102 CL1_1608 d888e296d65c367968b30ff055612eb5 218 Gene3D G3DSA:3.20.20.140 1 217 1.4E-45 T 30-10-2018 CL1_1608 d888e296d65c367968b30ff055612eb5 218 SUPERFAMILY SSF89550 6 214 1.96E-36 T 30-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CL1_1608 d888e296d65c367968b30ff055612eb5 218 SMART SM00481 6 78 4.9E-10 T 30-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal CL1_1608 d888e296d65c367968b30ff055612eb5 218 Pfam PF02811 PHP domain 7 81 1.7E-7 T 30-10-2018 IPR004013 PHP domain GO:0003824 CL1_0406 9d1e4b75f934aa97af865bead58be857 67 Gene3D G3DSA:1.10.20.10 1 67 2.9E-25 T 30-10-2018 IPR009072 Histone-fold GO:0046982 CL1_0406 9d1e4b75f934aa97af865bead58be857 67 Pfam PF00808 Histone-like transcription factor (CBF/NF-Y) and archaeal histone 2 65 2.7E-21 T 30-10-2018 IPR003958 Transcription factor CBF/NF-Y/archaeal histone domain CL1_0406 9d1e4b75f934aa97af865bead58be857 67 SUPERFAMILY SSF47113 3 66 1.45E-20 T 30-10-2018 IPR009072 Histone-fold GO:0046982 CL1_1612 037083c27a3fbf3a1ac63664041470e6 128 Pfam PF05763 Protein of unknown function (DUF835) 10 125 1.3E-23 T 30-10-2018 IPR008553 Domain of unknown function DUF835 CL1_0439 57ff18cad433b4633346237c946e7145 82 ProSitePatterns PS01110 RNA polymerases H / 23 Kd subunits signature. 12 25 - T 30-10-2018 IPR020608 RNA polymerase, subunit H/Rpb5, conserved site Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 CL1_0439 57ff18cad433b4633346237c946e7145 82 Pfam PF01191 RNA polymerase Rpb5, C-terminal domain 7 79 2.1E-32 T 30-10-2018 IPR000783 RNA polymerase, subunit H/Rpb5 C-terminal GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 CL1_0439 57ff18cad433b4633346237c946e7145 82 Hamap MF_00025 DNA-directed RNA polymerase subunit H [rpoH]. 7 80 23.965 T 30-10-2018 IPR020609 Archaeal RpoH /eukaryotic RPB5 RNA polymerase subunit GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 CL1_0439 57ff18cad433b4633346237c946e7145 82 SUPERFAMILY SSF55287 7 80 1.57E-28 T 30-10-2018 IPR035913 RPB5-like RNA polymerase subunit superfamily Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 CL1_0439 57ff18cad433b4633346237c946e7145 82 ProDom PD005155 RNA POLYMERASE DNA-DIRECTED SUBUNIT NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION II H POLYPEPTIDE 37 79 1.0E-17 T 30-10-2018 IPR000783 RNA polymerase, subunit H/Rpb5 C-terminal GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 CL1_0439 57ff18cad433b4633346237c946e7145 82 Gene3D G3DSA:3.90.940.20 1 82 4.0E-37 T 30-10-2018 IPR035913 RPB5-like RNA polymerase subunit superfamily Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 CL1_1396 84495a0d2e4e93ce4ba1bcb2b5df18e3 288 Pfam PF07722 Peptidase C26 3 222 1.3E-57 T 30-10-2018 IPR011697 Peptidase C26 GO:0016787 Reactome: R-HSA-6798695 CL1_1396 84495a0d2e4e93ce4ba1bcb2b5df18e3 288 SUPERFAMILY SSF52317 3 243 4.29E-37 T 30-10-2018 IPR029062 Class I glutamine amidotransferase-like CL1_1396 84495a0d2e4e93ce4ba1bcb2b5df18e3 288 Gene3D G3DSA:3.40.50.880 1 250 2.0E-70 T 30-10-2018 IPR029062 Class I glutamine amidotransferase-like CL1_0442 5de6a8147fa8603b8ff3fdd853e2e956 391 Pfam PF04998 RNA polymerase Rpb1, domain 5 28 332 5.0E-57 T 30-10-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CL1_0442 5de6a8147fa8603b8ff3fdd853e2e956 391 SUPERFAMILY SSF64484 29 385 6.41E-107 T 30-10-2018 CL1_0442 5de6a8147fa8603b8ff3fdd853e2e956 391 Hamap MF_00411 DNA-directed RNA polymerase subunit A'' [rpoA2]. 3 385 41.35 T 30-10-2018 IPR012757 DNA-directed RNA polymerase subunit A'' GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CL1_0442 5de6a8147fa8603b8ff3fdd853e2e956 391 Gene3D G3DSA:1.10.150.390 333 378 2.2E-23 T 30-10-2018 CL1_0442 5de6a8147fa8603b8ff3fdd853e2e956 391 TIGRFAM TIGR02389 RNA_pol_rpoA2: DNA-directed RNA polymerase, subunit A'' 16 382 2.2E-152 T 30-10-2018 IPR012757 DNA-directed RNA polymerase subunit A'' GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CL1_1882 702f6ec4fe2a965fbd0ed99cfe712be4 88 SUPERFAMILY SSF101386 3 71 2.62E-19 T 30-10-2018 CL1_1882 702f6ec4fe2a965fbd0ed99cfe712be4 88 Gene3D G3DSA:1.10.287.1080 1 71 9.1E-26 T 30-10-2018 CL1_1882 702f6ec4fe2a965fbd0ed99cfe712be4 88 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 15 75 1.5E-14 T 30-10-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core CL1_2031 f946b2a8727b366c771e5a70b5910c8a 455 PIRSF PIRSF004919 1 455 3.0E-157 T 30-10-2018 IPR025502 TldD CL1_2031 f946b2a8727b366c771e5a70b5910c8a 455 Gene3D G3DSA:3.30.2290.10 1 209 4.5E-16 T 30-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal CL1_2031 f946b2a8727b366c771e5a70b5910c8a 455 SUPERFAMILY SSF111283 2 450 1.83E-96 T 30-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 CL1_2031 f946b2a8727b366c771e5a70b5910c8a 455 Pfam PF01523 Putative modulator of DNA gyrase 19 310 3.9E-45 T 30-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 CL1_1603 376edf88881817ea4dfb93ed3e0fdf23 245 TIGRFAM TIGR01969 minD_arch: cell division ATPase MinD 3 236 6.1E-101 T 30-10-2018 IPR010224 ATP binding protein MinD, archaea CL1_1603 376edf88881817ea4dfb93ed3e0fdf23 245 PIRSF PIRSF003092 1 242 5.1E-57 T 30-10-2018 IPR025501 ATP binding protein MinD CL1_1603 376edf88881817ea4dfb93ed3e0fdf23 245 Pfam PF13614 AAA domain 3 147 2.0E-27 T 30-10-2018 IPR025669 AAA domain CL1_1603 376edf88881817ea4dfb93ed3e0fdf23 245 Gene3D G3DSA:3.40.50.300 1 236 2.3E-75 T 30-10-2018 CL1_1603 376edf88881817ea4dfb93ed3e0fdf23 245 SUPERFAMILY SSF52540 1 235 7.82E-65 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_1593 38550de990183ef97be5dafba27dea44 455 PRINTS PR00981 Seryl-tRNA synthetase signature 285 297 1.3E-32 T 30-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CL1_1593 38550de990183ef97be5dafba27dea44 455 PRINTS PR00981 Seryl-tRNA synthetase signature 354 370 1.3E-32 T 30-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CL1_1593 38550de990183ef97be5dafba27dea44 455 PRINTS PR00981 Seryl-tRNA synthetase signature 297 310 1.3E-32 T 30-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CL1_1593 38550de990183ef97be5dafba27dea44 455 PRINTS PR00981 Seryl-tRNA synthetase signature 337 350 1.3E-32 T 30-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CL1_1593 38550de990183ef97be5dafba27dea44 455 PRINTS PR00981 Seryl-tRNA synthetase signature 372 388 1.3E-32 T 30-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CL1_1593 38550de990183ef97be5dafba27dea44 455 TIGRFAM TIGR00414 serS: serine--tRNA ligase 1 438 2.3E-161 T 30-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CL1_1593 38550de990183ef97be5dafba27dea44 455 Gene3D G3DSA:1.10.287.40 1 107 3.6E-34 T 30-10-2018 CL1_1593 38550de990183ef97be5dafba27dea44 455 PIRSF PIRSF001529 1 447 1.6E-153 T 30-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CL1_1593 38550de990183ef97be5dafba27dea44 455 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 443 41.813 T 30-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CL1_1593 38550de990183ef97be5dafba27dea44 455 SUPERFAMILY SSF46589 1 115 1.26E-27 T 30-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 CL1_1593 38550de990183ef97be5dafba27dea44 455 Gene3D G3DSA:3.30.930.10 108 455 1.3E-134 T 30-10-2018 CL1_1593 38550de990183ef97be5dafba27dea44 455 SUPERFAMILY SSF55681 157 446 1.47E-87 T 30-10-2018 CL1_1593 38550de990183ef97be5dafba27dea44 455 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 109 1.6E-27 T 30-10-2018 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: R-HSA-2408557|Reactome: R-HSA-379716 CL1_1593 38550de990183ef97be5dafba27dea44 455 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 243 421 8.9E-39 T 30-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CL1_0894 8f276f7f355cdd2096f5a8d885ba5852 624 TIGRFAM TIGR00733 TIGR00733: oligopeptide transporter, OPT family 15 591 2.8E-253 T 30-10-2018 IPR004814 Oligopeptide transporter OPT CL1_0894 8f276f7f355cdd2096f5a8d885ba5852 624 TIGRFAM TIGR00728 OPT_sfam: oligopeptide transporter, OPT superfamily 9 594 1.2E-121 T 30-10-2018 IPR004813 Oligopeptide transporter, OPT superfamily GO:0055085 CL1_0894 8f276f7f355cdd2096f5a8d885ba5852 624 Pfam PF03169 OPT oligopeptide transporter protein 15 589 9.5E-104 T 30-10-2018 IPR004813 Oligopeptide transporter, OPT superfamily GO:0055085 CL1_0343 093ca06b65e425b710635707256c7718 350 SMART SM00829 16 345 2.6E-6 T 30-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CL1_0343 093ca06b65e425b710635707256c7718 350 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 138 2.4E-36 T 30-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CL1_0343 093ca06b65e425b710635707256c7718 350 Pfam PF00107 Zinc-binding dehydrogenase 178 306 2.4E-29 T 30-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CL1_0343 093ca06b65e425b710635707256c7718 350 SUPERFAMILY SSF50129 3 177 1.52E-54 T 30-10-2018 IPR011032 GroES-like superfamily CL1_0343 093ca06b65e425b710635707256c7718 350 TIGRFAM TIGR00692 tdh: L-threonine 3-dehydrogenase 7 346 1.4E-178 T 30-10-2018 IPR004627 L-threonine 3-dehydrogenase GO:0006567|GO:0008270|GO:0008743|GO:0055114 KEGG: 00260+1.1.1.103|MetaCyc: PWY-7378 CL1_0343 093ca06b65e425b710635707256c7718 350 Gene3D G3DSA:3.90.180.10 21 338 2.1E-134 T 30-10-2018 CL1_0343 093ca06b65e425b710635707256c7718 350 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 66 80 - T 30-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CL1_0343 093ca06b65e425b710635707256c7718 350 SUPERFAMILY SSF51735 142 313 1.71E-34 T 30-10-2018 IPR036291 NAD(P)-binding domain superfamily CL1_0343 093ca06b65e425b710635707256c7718 350 Gene3D G3DSA:3.40.50.720 157 291 2.1E-134 T 30-10-2018 CL1_0343 093ca06b65e425b710635707256c7718 350 Hamap MF_00627 L-threonine 3-dehydrogenase [tdh]. 5 347 53.705 T 30-10-2018 IPR004627 L-threonine 3-dehydrogenase GO:0006567|GO:0008270|GO:0008743|GO:0055114 KEGG: 00260+1.1.1.103|MetaCyc: PWY-7378 CL1_1325 d53822a96a84e1c23f9474dc29851a75 158 SUPERFAMILY SSF56784 2 126 1.79E-16 T 30-10-2018 IPR036412 HAD-like superfamily CL1_1325 d53822a96a84e1c23f9474dc29851a75 158 Gene3D G3DSA:3.40.50.1000 3 157 2.0E-25 T 30-10-2018 IPR023214 HAD superfamily CL1_1325 d53822a96a84e1c23f9474dc29851a75 158 Pfam PF03031 NLI interacting factor-like phosphatase 3 157 4.7E-7 T 30-10-2018 IPR004274 FCP1 homology domain CL1_1325 d53822a96a84e1c23f9474dc29851a75 158 TIGRFAM TIGR01685 MDP-1: magnesium-dependent phosphatase-1 3 154 9.1E-24 T 30-10-2018 IPR010036 Magnesium-dependent phosphatase-1, eukaryotic/archaeal-type GO:0016791 CL1_1325 d53822a96a84e1c23f9474dc29851a75 158 TIGRFAM TIGR01681 HAD-SF-IIIC: HAD phosphatase, family IIIC 3 130 2.7E-13 T 30-10-2018 IPR010033 HAD-superfamily phosphatase, subfamily IIIC CL1_1166 32adb0821b63b08660f2e0a6250c6599 332 SUPERFAMILY SSF161098 108 308 3.92E-8 T 30-10-2018 IPR035906 MetI-like superfamily CL1_1166 32adb0821b63b08660f2e0a6250c6599 332 Gene3D G3DSA:1.10.3720.10 107 324 1.5E-8 T 30-10-2018 IPR035906 MetI-like superfamily CL1_1166 32adb0821b63b08660f2e0a6250c6599 332 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 123 319 1.1E-9 T 30-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 CL1_0811 287e563dbe0b524c5aff54aed4219f7e 235 ProDom PD359573 MEMBRANE TRANSMEMBRANE AF2132 PROTEIN 13 209 4.0E-75 T 30-10-2018 CL1_1530 c8d80afe07c75fe801335b0d89b8f5fa 55 Pfam PF04021 Class III signal peptide 5 28 1.2E-6 T 30-10-2018 IPR007166 Class III signal peptide motif CL1_1201 244456502f3ee729a9eabe9419777544 71 SUPERFAMILY SSF46785 5 55 1.28E-5 T 30-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CL1_0173 9ccfb379ff16f67ccb5a04546d876b49 490 Pfam PF09852 Predicted membrane protein (DUF2079) 28 465 2.8E-57 T 30-10-2018 IPR018650 Sulfolobus virus STSV1, Orf64 CL1_0229 7fe180201d52d5cde8ff6547714158dd 49 Hamap MF_00615 DNA-directed RNA polymerase subunit P [rpoP]. 6 49 16.941 T 30-10-2018 IPR023464 DNA-directed RNA polymerase subunit P (Rpo12) GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CL1_0229 7fe180201d52d5cde8ff6547714158dd 49 Pfam PF03604 DNA directed RNA polymerase, 7 kDa subunit 6 39 7.4E-11 T 30-10-2018 IPR006591 RNA polymerase archaeal subunit P/eukaryotic subunit RPABC4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 CL1_0229 7fe180201d52d5cde8ff6547714158dd 49 SUPERFAMILY SSF63393 4 48 7.32E-13 T 30-10-2018 IPR029040 RNA polymerase subunit RPABC4/transcription elongation factor Spt4 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-75955 CL1_0229 7fe180201d52d5cde8ff6547714158dd 49 SMART SM00659 4 49 1.2E-20 T 30-10-2018 IPR006591 RNA polymerase archaeal subunit P/eukaryotic subunit RPABC4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 CL1_0229 7fe180201d52d5cde8ff6547714158dd 49 Gene3D G3DSA:2.20.28.30 1 49 1.3E-23 T 30-10-2018 CL1_1685 3de1744695e57992f951eb9241559317 354 SUPERFAMILY SSF50331 237 349 1.46E-13 T 30-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal CL1_1685 3de1744695e57992f951eb9241559317 354 SMART SM00382 28 211 6.8E-16 T 30-10-2018 IPR003593 AAA+ ATPase domain CL1_1685 3de1744695e57992f951eb9241559317 354 TIGRFAM TIGR01187 potA: polyamine ABC transporter, ATP-binding protein 34 314 1.7E-109 T 30-10-2018 IPR005893 Spermidine/putrescine ABC transporter, ATP-binding subunit GO:0015417|GO:0015846|GO:0043190 CL1_1685 3de1744695e57992f951eb9241559317 354 Pfam PF00005 ABC transporter 19 161 1.4E-34 T 30-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CL1_1685 3de1744695e57992f951eb9241559317 354 Gene3D G3DSA:2.40.50.140 289 340 3.2E-7 T 30-10-2018 CL1_1685 3de1744695e57992f951eb9241559317 354 Pfam PF08402 TOBE domain 276 349 8.8E-7 T 30-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 CL1_1685 3de1744695e57992f951eb9241559317 354 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 30-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CL1_1685 3de1744695e57992f951eb9241559317 354 SUPERFAMILY SSF52540 4 244 8.05E-90 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_1685 3de1744695e57992f951eb9241559317 354 Gene3D G3DSA:2.40.50.100 238 344 3.2E-7 T 30-10-2018 CL1_1685 3de1744695e57992f951eb9241559317 354 Gene3D G3DSA:3.40.50.300 1 237 6.6E-80 T 30-10-2018 CL1_1755 9e7f7d27efeeeafe09314d4ffe1223f1 555 Gene3D G3DSA:3.40.50.300 310 530 2.0E-56 T 30-10-2018 CL1_1755 9e7f7d27efeeeafe09314d4ffe1223f1 555 Gene3D G3DSA:3.40.50.300 127 283 4.7E-23 T 30-10-2018 CL1_1755 9e7f7d27efeeeafe09314d4ffe1223f1 555 Pfam PF09378 HAS barrel domain 8 99 9.0E-8 T 30-10-2018 IPR018538 Helicase HerA, barrel domain CL1_1755 9e7f7d27efeeeafe09314d4ffe1223f1 555 Pfam PF01935 Domain of unknown function DUF87 141 370 2.4E-43 T 30-10-2018 IPR002789 Helicase HerA, central domain CL1_1755 9e7f7d27efeeeafe09314d4ffe1223f1 555 SUPERFAMILY SSF52540 112 520 1.56E-41 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_1755 9e7f7d27efeeeafe09314d4ffe1223f1 555 Pfam PF05872 Bacterial protein of unknown function (DUF853) 400 502 2.0E-5 T 30-10-2018 IPR033186 Helicase HerA-like C-terminal CL1_1563 5d056c3a98134b7e86113352c4967ce1 244 Pfam PF03205 Molybdopterin guanine dinucleotide synthesis protein B 4 111 6.8E-18 T 30-10-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 CL1_1563 5d056c3a98134b7e86113352c4967ce1 244 Pfam PF04060 Putative Fe-S cluster 160 191 5.0E-9 T 30-10-2018 IPR007202 4Fe-4S domain GO:0051536 CL1_1563 5d056c3a98134b7e86113352c4967ce1 244 SUPERFAMILY SSF52540 1 107 1.83E-11 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_1563 5d056c3a98134b7e86113352c4967ce1 244 Gene3D G3DSA:3.40.50.300 1 157 1.7E-28 T 30-10-2018 CL1_1563 5d056c3a98134b7e86113352c4967ce1 244 TIGRFAM TIGR00176 mobB: molybdopterin-guanine dinucleotide biosynthesis protein B 5 153 2.5E-23 T 30-10-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 CL1_1563 5d056c3a98134b7e86113352c4967ce1 244 Gene3D G3DSA:3.20.20.20 158 221 6.4E-6 T 30-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CL1_1338 e132378403c5420e63ad5c8fee007ed9 374 Gene3D G3DSA:1.20.1250.20 1 190 4.3E-41 T 30-10-2018 CL1_1338 e132378403c5420e63ad5c8fee007ed9 374 SUPERFAMILY SSF103473 2 360 1.05E-71 T 30-10-2018 IPR036259 MFS transporter superfamily CL1_1338 e132378403c5420e63ad5c8fee007ed9 374 Gene3D G3DSA:1.20.1250.20 193 369 1.2E-27 T 30-10-2018 CL1_1338 e132378403c5420e63ad5c8fee007ed9 374 Pfam PF07690 Major Facilitator Superfamily 11 330 2.1E-44 T 30-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CL1_0820 43974d539c8f79c0c859e16367c68d79 60 Pfam PF10049 Protein of unknown function (DUF2283) 2 49 6.5E-20 T 30-10-2018 IPR019270 Protein of unknown function DUF2283 CL1_1740 419fd2211adc305ea6b6583fdba9b8cf 204 PIRSF PIRSF015877 1 199 1.1E-66 T 30-10-2018 IPR012041 Uncharacterised conserved protein UCP015877, zinc finger-containing CL1_1740 419fd2211adc305ea6b6583fdba9b8cf 204 Pfam PF01873 Domain found in IF2B/IF5 2 34 5.1E-5 T 30-10-2018 IPR002735 Translation initiation factor IF2/IF5 GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 CL1_1740 419fd2211adc305ea6b6583fdba9b8cf 204 SUPERFAMILY SSF75689 4 38 3.27E-5 T 30-10-2018 IPR016190 Translation initiation factor IF2/IF5, zinc-binding GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 CL1_0252 1975305e7fa5e4c1091e9940b730497c 181 Pfam PF06195 Protein of unknown function (DUF996) 25 155 6.6E-23 T 30-10-2018 IPR010397 Protein of unknown function DUF996 CL1_1484 5bae642b6238cc67d3321ac97e1d8864 298 SUPERFAMILY SSF47954 206 297 5.92E-29 T 30-10-2018 IPR036915 Cyclin-like superfamily CL1_1484 5bae642b6238cc67d3321ac97e1d8864 298 SMART SM00385 115 196 6.1E-13 T 30-10-2018 IPR013763 Cyclin-like CL1_1484 5bae642b6238cc67d3321ac97e1d8864 298 SMART SM00385 209 290 2.1E-10 T 30-10-2018 IPR013763 Cyclin-like CL1_1484 5bae642b6238cc67d3321ac97e1d8864 298 Pfam PF00382 Transcription factor TFIIB repeat 211 281 1.6E-19 T 30-10-2018 IPR013150 Transcription factor TFIIB, cyclin-like domain GO:0017025 CL1_1484 5bae642b6238cc67d3321ac97e1d8864 298 Pfam PF00382 Transcription factor TFIIB repeat 118 187 2.2E-19 T 30-10-2018 IPR013150 Transcription factor TFIIB, cyclin-like domain GO:0017025 CL1_1484 5bae642b6238cc67d3321ac97e1d8864 298 Gene3D G3DSA:1.10.472.10 206 298 9.1E-27 T 30-10-2018 CL1_1484 5bae642b6238cc67d3321ac97e1d8864 298 Pfam PF08271 TFIIB zinc-binding 1 42 2.0E-17 T 30-10-2018 IPR013137 Zinc finger, TFIIB-type CL1_1484 5bae642b6238cc67d3321ac97e1d8864 298 Hamap MF_00383 Transcription initiation factor IIB [tfb]. 1 296 44.369 T 30-10-2018 IPR023484 Transcription initiation factor TFIIB, archaea CL1_1484 5bae642b6238cc67d3321ac97e1d8864 298 SUPERFAMILY SSF47954 109 202 6.81E-26 T 30-10-2018 IPR036915 Cyclin-like superfamily CL1_1484 5bae642b6238cc67d3321ac97e1d8864 298 PRINTS PR00685 Transcription initiation factor IIB signature 183 198 1.5E-57 T 30-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 CL1_1484 5bae642b6238cc67d3321ac97e1d8864 298 PRINTS PR00685 Transcription initiation factor IIB signature 276 290 1.5E-57 T 30-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 CL1_1484 5bae642b6238cc67d3321ac97e1d8864 298 PRINTS PR00685 Transcription initiation factor IIB signature 14 34 1.5E-57 T 30-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 CL1_1484 5bae642b6238cc67d3321ac97e1d8864 298 PRINTS PR00685 Transcription initiation factor IIB signature 210 228 1.5E-57 T 30-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 CL1_1484 5bae642b6238cc67d3321ac97e1d8864 298 PRINTS PR00685 Transcription initiation factor IIB signature 36 49 1.5E-57 T 30-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 CL1_1484 5bae642b6238cc67d3321ac97e1d8864 298 PRINTS PR00685 Transcription initiation factor IIB signature 244 260 1.5E-57 T 30-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 CL1_1484 5bae642b6238cc67d3321ac97e1d8864 298 PRINTS PR00685 Transcription initiation factor IIB signature 49 70 1.5E-57 T 30-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 CL1_1484 5bae642b6238cc67d3321ac97e1d8864 298 PRINTS PR00685 Transcription initiation factor IIB signature 157 176 1.5E-57 T 30-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 CL1_1484 5bae642b6238cc67d3321ac97e1d8864 298 SUPERFAMILY SSF57783 1 45 1.19E-15 T 30-10-2018 CL1_1484 5bae642b6238cc67d3321ac97e1d8864 298 ProSitePatterns PS00782 Transcription factor TFIIB repeat signature. 243 258 - T 30-10-2018 IPR023486 Transcription factor TFIIB, conserved site Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-674695|Reactome: R-HSA-6807505|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-76042 CL1_1484 5bae642b6238cc67d3321ac97e1d8864 298 ProSitePatterns PS00782 Transcription factor TFIIB repeat signature. 149 164 - T 30-10-2018 IPR023486 Transcription factor TFIIB, conserved site Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-674695|Reactome: R-HSA-6807505|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-76042 CL1_1484 5bae642b6238cc67d3321ac97e1d8864 298 Gene3D G3DSA:1.10.472.170 1 197 8.6E-66 T 30-10-2018 CL1_0828 13f1bae39218e4f1814dd103ac6e2a6f 297 Gene3D G3DSA:3.90.550.10 2 243 1.0E-43 T 30-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases CL1_0828 13f1bae39218e4f1814dd103ac6e2a6f 297 Pfam PF00535 Glycosyl transferase family 2 10 172 2.0E-25 T 30-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CL1_0828 13f1bae39218e4f1814dd103ac6e2a6f 297 SUPERFAMILY SSF53448 5 259 2.51E-41 T 30-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases CL1_0501 34ed99de9b7c11831bfa395893e01855 388 Gene3D G3DSA:2.40.50.140 332 383 3.0E-8 T 30-10-2018 CL1_0501 34ed99de9b7c11831bfa395893e01855 388 SUPERFAMILY SSF50249 332 382 4.71E-5 T 30-10-2018 IPR012340 Nucleic acid-binding, OB-fold CL1_0501 34ed99de9b7c11831bfa395893e01855 388 Pfam PF04981 NMD3 family 6 276 2.3E-63 T 30-10-2018 IPR007064 Nmd3, N-terminal CL1_1241 aa6cfd5aac71fdd80b4f36d7b6f02041 372 Gene3D G3DSA:3.40.50.1980 25 172 1.9E-59 T 30-10-2018 CL1_1241 aa6cfd5aac71fdd80b4f36d7b6f02041 372 SUPERFAMILY SSF53807 36 348 1.73E-59 T 30-10-2018 CL1_1241 aa6cfd5aac71fdd80b4f36d7b6f02041 372 Pfam PF01497 Periplasmic binding protein 53 293 1.2E-25 T 30-10-2018 IPR002491 ABC transporter periplasmic binding domain CL1_1241 aa6cfd5aac71fdd80b4f36d7b6f02041 372 Gene3D G3DSA:3.40.50.1980 173 368 2.0E-84 T 30-10-2018 CL1_1038 ae2a9f0eb56ee00e4ebcd57b3767338d 101 SUPERFAMILY SSF160363 4 93 1.09E-34 T 30-10-2018 IPR023129 MTH889-like domain superfamily CL1_1038 ae2a9f0eb56ee00e4ebcd57b3767338d 101 ProDom PD012512 ARCHAEA PH1931 STS176 TA1183 MJ0319 PRECURSOR TVG0378908 UNCHARACTERIZED DUF211 AF1549 12 95 9.0E-39 T 30-10-2018 IPR003831 Protein of unknown function DUF211 CL1_1038 ae2a9f0eb56ee00e4ebcd57b3767338d 101 Pfam PF02680 Uncharacterized ArCR, COG1888 5 90 6.7E-38 T 30-10-2018 IPR003831 Protein of unknown function DUF211 CL1_1038 ae2a9f0eb56ee00e4ebcd57b3767338d 101 Gene3D G3DSA:3.30.70.1340 1 86 1.2E-34 T 30-10-2018 IPR023129 MTH889-like domain superfamily CL1_1300 99e9d5feb97e542e526d214f8aefd7a8 151 Gene3D G3DSA:3.30.980.10 2 76 4.4E-33 T 30-10-2018 CL1_1300 99e9d5feb97e542e526d214f8aefd7a8 151 Gene3D G3DSA:3.30.54.20 77 119 1.1E-23 T 30-10-2018 CL1_1300 99e9d5feb97e542e526d214f8aefd7a8 151 SUPERFAMILY SSF55186 5 148 4.45E-38 T 30-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 CL1_0361 86ee4bea47101a65f962eca694323fb9 272 Pfam PF14336 Domain of unknown function (DUF4392) 3 260 5.1E-65 T 30-10-2018 IPR025504 Domain of unknown function DUF4392 KEGG: 00471+4.2.1.48 CL1_0361 86ee4bea47101a65f962eca694323fb9 272 Gene3D G3DSA:3.90.1640.20 1 269 1.4E-101 T 30-10-2018 CL1_1333 5d1cf4c32b54f262ab1f5a0664d09aa5 306 Pfam PF01112 Asparaginase 3 297 6.3E-93 T 30-10-2018 IPR000246 Peptidase T2, asparaginase 2 GO:0016787 CL1_1333 5d1cf4c32b54f262ab1f5a0664d09aa5 306 Gene3D G3DSA:3.60.20.30 176 303 2.9E-33 T 30-10-2018 CL1_1333 5d1cf4c32b54f262ab1f5a0664d09aa5 306 SUPERFAMILY SSF56235 18 299 6.43E-87 T 30-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CL1_1642 7d4c7ded8448080968b85a4734a99bf2 226 SUPERFAMILY SSF50891 85 215 1.82E-52 T 30-10-2018 IPR029000 Cyclophilin-like domain superfamily CL1_1642 7d4c7ded8448080968b85a4734a99bf2 226 SMART SM00796 1 199 3.8E-114 T 30-10-2018 IPR003833 Carboxyltransferase domain, subdomain C and D CL1_1642 7d4c7ded8448080968b85a4734a99bf2 226 Gene3D G3DSA:2.40.100.10 84 224 2.2E-65 T 30-10-2018 IPR029000 Cyclophilin-like domain superfamily CL1_1642 7d4c7ded8448080968b85a4734a99bf2 226 Pfam PF02682 Carboxyltransferase domain, subdomain C and D 1 199 4.5E-79 T 30-10-2018 IPR003833 Carboxyltransferase domain, subdomain C and D CL1_1642 7d4c7ded8448080968b85a4734a99bf2 226 SUPERFAMILY SSF160467 2 90 3.92E-22 T 30-10-2018 CL1_1642 7d4c7ded8448080968b85a4734a99bf2 226 TIGRFAM TIGR00370 TIGR00370: sensor histidine kinase inhibitor, KipI family 6 208 2.0E-74 T 30-10-2018 IPR010016 KipI family KEGG: 00480+3.5.2.9|MetaCyc: PWY-4041|MetaCyc: PWY-7942 CL1_1642 7d4c7ded8448080968b85a4734a99bf2 226 Gene3D G3DSA:3.30.1360.40 1 82 3.3E-26 T 30-10-2018 CL1_2012 b89cfbea4ffea0d11f2afe74b05545e7 196 Pfam PF01955 Adenosylcobinamide amidohydrolase 10 182 9.7E-46 T 30-10-2018 IPR002808 Adenosylcobinamide amidohydrolase, CbiZ CL1_1913 995a340b80d0c362b92ccfd7b3a304e9 120 Gene3D G3DSA:2.40.50.140 9 120 7.2E-41 T 30-10-2018 CL1_1913 995a340b80d0c362b92ccfd7b3a304e9 120 ProDom PD005579 INITIATION FACTOR TRANSLATION 1A BIOSYNTHESIS EUKARYOTIC EIF-1A AIF-1A EIF-4C 1A 51 108 1.0E-26 T 30-10-2018 IPR001253 Translation initiation factor 1A (eIF-1A) GO:0003743|GO:0006413 CL1_1913 995a340b80d0c362b92ccfd7b3a304e9 120 ProSitePatterns PS01262 Eukaryotic initiation factor 1A signature. 39 61 - T 30-10-2018 IPR018104 Translation initiation factor 1A (eIF-1A), conserved site GO:0003743|GO:0006413 CL1_1913 995a340b80d0c362b92ccfd7b3a304e9 120 TIGRFAM TIGR00523 eIF-1A: translation initiation factor eIF-1A 17 108 1.6E-34 T 30-10-2018 IPR001253 Translation initiation factor 1A (eIF-1A) GO:0003743|GO:0006413 CL1_1913 995a340b80d0c362b92ccfd7b3a304e9 120 Hamap MF_00216 Translation initiation factor 1A [eif1a]. 15 109 28.076 T 30-10-2018 IPR001253 Translation initiation factor 1A (eIF-1A) GO:0003743|GO:0006413 CL1_1913 995a340b80d0c362b92ccfd7b3a304e9 120 Pfam PF01176 Translation initiation factor 1A / IF-1 30 93 1.8E-20 T 30-10-2018 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 CL1_1913 995a340b80d0c362b92ccfd7b3a304e9 120 SUPERFAMILY SSF50249 4 112 1.23E-31 T 30-10-2018 IPR012340 Nucleic acid-binding, OB-fold CL1_1913 995a340b80d0c362b92ccfd7b3a304e9 120 SMART SM00652 26 109 9.6E-44 T 30-10-2018 IPR001253 Translation initiation factor 1A (eIF-1A) GO:0003743|GO:0006413 CL1_1748 0b3856eb620fc954efa179634b141c1c 420 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 250 418 6.1E-17 T 30-10-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 CL1_1748 0b3856eb620fc954efa179634b141c1c 420 Gene3D G3DSA:3.40.50.150 74 413 4.0E-93 T 30-10-2018 CL1_1748 0b3856eb620fc954efa179634b141c1c 420 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 10 411 1.2E-68 T 30-10-2018 CL1_1748 0b3856eb620fc954efa179634b141c1c 420 Gene3D G3DSA:3.40.1350.30 113 261 4.0E-93 T 30-10-2018 CL1_1748 0b3856eb620fc954efa179634b141c1c 420 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 401 411 - T 30-10-2018 IPR030391 RNA methyltransferase TrmA, conserved site CL1_1748 0b3856eb620fc954efa179634b141c1c 420 Gene3D G3DSA:2.40.50.140 2 62 6.4E-14 T 30-10-2018 CL1_1748 0b3856eb620fc954efa179634b141c1c 420 SUPERFAMILY SSF53335 61 418 4.07E-66 T 30-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CL1_1748 0b3856eb620fc954efa179634b141c1c 420 SUPERFAMILY SSF50249 5 59 7.42E-8 T 30-10-2018 IPR012340 Nucleic acid-binding, OB-fold CL1_0632 17921718bcef42e90cbe765290d7c9d5 388 Pfam PF07690 Major Facilitator Superfamily 12 307 4.0E-18 T 30-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CL1_0632 17921718bcef42e90cbe765290d7c9d5 388 SUPERFAMILY SSF103473 9 378 1.2E-28 T 30-10-2018 IPR036259 MFS transporter superfamily CL1_0632 17921718bcef42e90cbe765290d7c9d5 388 Gene3D G3DSA:1.20.1250.20 207 382 5.9E-10 T 30-10-2018 CL1_0632 17921718bcef42e90cbe765290d7c9d5 388 Gene3D G3DSA:1.20.1250.20 1 197 3.1E-14 T 30-10-2018 CL1_1122 344c41d008fe1781d6fc85c89f8aec43 445 SUPERFAMILY SSF53383 34 441 9.74E-125 T 30-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase CL1_1122 344c41d008fe1781d6fc85c89f8aec43 445 Gene3D G3DSA:3.90.1150.10 15 438 1.4E-150 T 30-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 CL1_1122 344c41d008fe1781d6fc85c89f8aec43 445 PIRSF PIRSF000521 2 143 2.1E-7 T 30-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CL1_1122 344c41d008fe1781d6fc85c89f8aec43 445 PIRSF PIRSF000521 130 443 2.5E-55 T 30-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CL1_1122 344c41d008fe1781d6fc85c89f8aec43 445 Gene3D G3DSA:3.40.640.10 72 340 1.4E-150 T 30-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 CL1_1122 344c41d008fe1781d6fc85c89f8aec43 445 Pfam PF00202 Aminotransferase class-III 35 438 4.0E-114 T 30-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CL1_1688 a1000f688d0168c3e963fd17e2db4ae8 349 TIGRFAM TIGR04288 CGP_CTERM: CGP-CTERM domain 328 347 9.4E-8 T 30-10-2018 IPR027552 CGP-CTERM domain CL1_1972 d26586b5e6c448dad2e09c05d2a556f4 285 PIRSF PIRSF000388 1 265 3.3E-102 T 30-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 CL1_1972 d26586b5e6c448dad2e09c05d2a556f4 285 SUPERFAMILY SSF51621 4 262 9.42E-102 T 30-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 CL1_1972 d26586b5e6c448dad2e09c05d2a556f4 285 Pfam PF02548 Ketopantoate hydroxymethyltransferase 4 257 7.0E-106 T 30-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 CL1_1972 d26586b5e6c448dad2e09c05d2a556f4 285 Gene3D G3DSA:3.20.20.60 2 273 1.1E-108 T 30-10-2018 CL1_1972 d26586b5e6c448dad2e09c05d2a556f4 285 TIGRFAM TIGR00222 panB: 3-methyl-2-oxobutanoate hydroxymethyltransferase 12 262 4.4E-90 T 30-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 CL1_1972 d26586b5e6c448dad2e09c05d2a556f4 285 Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. 4 262 41.253 T 30-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 CL1_1071 208e98a13f7a2d759b84e731b385b05c 1128 SUPERFAMILY SSF52540 372 857 1.02E-37 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_1071 208e98a13f7a2d759b84e731b385b05c 1128 Pfam PF00271 Helicase conserved C-terminal domain 685 810 8.6E-17 T 30-10-2018 IPR001650 Helicase, C-terminal CL1_1071 208e98a13f7a2d759b84e731b385b05c 1128 SMART SM00487 265 439 4.5E-9 T 30-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CL1_1071 208e98a13f7a2d759b84e731b385b05c 1128 Gene3D G3DSA:3.40.50.300 263 428 1.3E-17 T 30-10-2018 CL1_1071 208e98a13f7a2d759b84e731b385b05c 1128 SUPERFAMILY SSF56024 150 215 9.42E-6 T 30-10-2018 CL1_1071 208e98a13f7a2d759b84e731b385b05c 1128 SUPERFAMILY SSF52540 268 453 6.39E-26 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_1071 208e98a13f7a2d759b84e731b385b05c 1128 SMART SM00490 691 810 1.5E-12 T 30-10-2018 IPR001650 Helicase, C-terminal CL1_1071 208e98a13f7a2d759b84e731b385b05c 1128 Gene3D G3DSA:3.40.50.300 634 844 9.1E-33 T 30-10-2018 CL1_1071 208e98a13f7a2d759b84e731b385b05c 1128 Pfam PF13091 PLD-like domain 37 209 1.3E-14 T 30-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 CL1_1240 5d5a80ed2968aa3d47ca83f759428edd 344 Pfam PF01032 FecCD transport family 21 339 7.6E-96 T 30-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 CL1_1240 5d5a80ed2968aa3d47ca83f759428edd 344 SUPERFAMILY SSF81345 4 339 1.44E-85 T 30-10-2018 IPR037294 ABC transporter, BtuC-like CL1_1240 5d5a80ed2968aa3d47ca83f759428edd 344 Gene3D G3DSA:1.10.3470.10 8 343 4.4E-105 T 30-10-2018 IPR037294 ABC transporter, BtuC-like CL1_1558 7e4bbabdd767ebf36f5a326bbc17a35c 251 Pfam PF12706 Beta-lactamase superfamily domain 66 218 1.2E-18 T 30-10-2018 IPR001279 Metallo-beta-lactamase CL1_1558 7e4bbabdd767ebf36f5a326bbc17a35c 251 SMART SM00849 39 217 8.7E-17 T 30-10-2018 IPR001279 Metallo-beta-lactamase CL1_1558 7e4bbabdd767ebf36f5a326bbc17a35c 251 SUPERFAMILY SSF56281 5 249 2.62E-42 T 30-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like CL1_1558 7e4bbabdd767ebf36f5a326bbc17a35c 251 Gene3D G3DSA:3.60.15.10 3 251 8.2E-51 T 30-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like CL1_0398 5e71b5046c7638df375efff5001a9c66 61 Hamap MF_00422 Protein translocase subunit SecE [secE]. 6 61 12.56 T 30-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CL1_0398 5e71b5046c7638df375efff5001a9c66 61 SUPERFAMILY SSF103456 3 58 2.48E-20 T 30-10-2018 IPR023391 Protein translocase SecE domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CL1_0398 5e71b5046c7638df375efff5001a9c66 61 TIGRFAM TIGR00327 secE_euk_arch: protein translocase SEC61 complex gamma subunit, archaeal and eukaryotic 5 60 4.4E-19 T 30-10-2018 IPR008158 Protein translocase SEC61 complex, gamma subunit GO:0015031|GO:0015450|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CL1_0398 5e71b5046c7638df375efff5001a9c66 61 ProSitePatterns PS01067 Protein secE/sec61-gamma signature. 11 39 - T 30-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CL1_0398 5e71b5046c7638df375efff5001a9c66 61 Gene3D G3DSA:1.20.5.820 1 61 9.9E-24 T 30-10-2018 IPR023391 Protein translocase SecE domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CL1_1417 4ba2cebd7184244ee4295720b4b83d39 224 Hamap MF_00457 UPF0173 metal-dependent hydrolase . 2 224 38.885 T 30-10-2018 IPR022877 Protein of unknown funcion UPF0173 CL1_1417 4ba2cebd7184244ee4295720b4b83d39 224 Gene3D G3DSA:3.60.15.10 2 224 1.2E-72 T 30-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like CL1_1417 4ba2cebd7184244ee4295720b4b83d39 224 SUPERFAMILY SSF56281 1 223 9.96E-40 T 30-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like CL1_1417 4ba2cebd7184244ee4295720b4b83d39 224 SMART SM00849 8 189 4.9E-18 T 30-10-2018 IPR001279 Metallo-beta-lactamase CL1_1417 4ba2cebd7184244ee4295720b4b83d39 224 Pfam PF13483 Beta-lactamase superfamily domain 3 189 6.8E-33 T 30-10-2018 CL1_1915 c172a57f5d62afa64cc076f6b6c014a6 238 SUPERFAMILY SSF54791 125 204 3.36E-18 T 30-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 CL1_1915 c172a57f5d62afa64cc076f6b6c014a6 238 Pfam PF00013 KH domain 39 86 4.0E-9 T 30-10-2018 IPR004088 K Homology domain, type 1 GO:0003723 CL1_1915 c172a57f5d62afa64cc076f6b6c014a6 238 Pfam PF00013 KH domain 142 189 4.2E-6 T 30-10-2018 IPR004088 K Homology domain, type 1 GO:0003723 CL1_1915 c172a57f5d62afa64cc076f6b6c014a6 238 TIGRFAM TIGR03665 arCOG04150: arCOG04150 universal archaeal KH domain protein 41 214 5.7E-69 T 30-10-2018 IPR019964 KH domain protein, archaea CL1_1915 c172a57f5d62afa64cc076f6b6c014a6 238 SUPERFAMILY SSF54791 40 114 6.53E-13 T 30-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 CL1_1915 c172a57f5d62afa64cc076f6b6c014a6 238 Gene3D G3DSA:3.30.1370.10 118 223 4.1E-33 T 30-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 CL1_1915 c172a57f5d62afa64cc076f6b6c014a6 238 SMART SM00322 35 105 7.4E-11 T 30-10-2018 IPR004087 K Homology domain GO:0003676 CL1_1915 c172a57f5d62afa64cc076f6b6c014a6 238 SMART SM00322 126 193 7.1E-7 T 30-10-2018 IPR004087 K Homology domain GO:0003676 CL1_1915 c172a57f5d62afa64cc076f6b6c014a6 238 Gene3D G3DSA:3.30.1370.10 35 117 3.4E-34 T 30-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 CL1_1478 5c79dde1f8909601d38143d572580b9e 253 SMART SM00382 26 209 8.4E-14 T 30-10-2018 IPR003593 AAA+ ATPase domain CL1_1478 5c79dde1f8909601d38143d572580b9e 253 Gene3D G3DSA:3.40.50.300 1 242 5.3E-70 T 30-10-2018 CL1_1478 5c79dde1f8909601d38143d572580b9e 253 SUPERFAMILY SSF52540 2 222 7.99E-65 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_1478 5c79dde1f8909601d38143d572580b9e 253 Pfam PF00005 ABC transporter 18 161 7.0E-28 T 30-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CL1_1786 934b920a9ef00dea1eb8c81de9f60397 248 Gene3D G3DSA:3.40.50.11590 103 218 7.9E-25 T 30-10-2018 CL1_1786 934b920a9ef00dea1eb8c81de9f60397 248 Pfam PF13938 Putative heavy-metal chelation 10 89 9.5E-12 T 30-10-2018 IPR025251 Domain of unknown function DUF4213 CL1_1786 934b920a9ef00dea1eb8c81de9f60397 248 Pfam PF04016 Putative heavy-metal chelation 102 244 6.7E-36 T 30-10-2018 IPR007161 Putative heavy-metal chelation domain CL1_1786 934b920a9ef00dea1eb8c81de9f60397 248 SUPERFAMILY SSF159713 3 245 1.83E-60 T 30-10-2018 CL1_1786 934b920a9ef00dea1eb8c81de9f60397 248 Gene3D G3DSA:3.30.390.100 29 222 7.9E-25 T 30-10-2018 CL1_1869 0580704b540a88d132e06bcd52275265 429 Gene3D G3DSA:3.40.640.10 38 280 1.7E-83 T 30-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 CL1_1869 0580704b540a88d132e06bcd52275265 429 Pfam PF00464 Serine hydroxymethyltransferase 11 390 1.6E-81 T 30-10-2018 IPR039429 Serine hydroxymethyltransferase-like domain KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 CL1_1869 0580704b540a88d132e06bcd52275265 429 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 5 418 43.012 T 30-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 CL1_1869 0580704b540a88d132e06bcd52275265 429 SUPERFAMILY SSF53383 7 428 2.15E-132 T 30-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase CL1_1869 0580704b540a88d132e06bcd52275265 429 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 220 236 - T 30-10-2018 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 CL1_1869 0580704b540a88d132e06bcd52275265 429 Gene3D G3DSA:3.90.1150.10 281 426 5.2E-53 T 30-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 CL1_1869 0580704b540a88d132e06bcd52275265 429 PIRSF PIRSF000412 3 426 1.5E-144 T 30-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 CL1_0118 a252b9d70fc4d95575f5424263de96fa 333 Gene3D G3DSA:3.40.50.720 16 318 5.5E-112 T 30-10-2018 CL1_0118 a252b9d70fc4d95575f5424263de96fa 333 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 10 318 1.1E-31 T 30-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 CL1_0118 a252b9d70fc4d95575f5424263de96fa 333 Gene3D G3DSA:3.40.50.720 95 286 5.5E-112 T 30-10-2018 CL1_0118 a252b9d70fc4d95575f5424263de96fa 333 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 149 176 - T 30-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 CL1_0118 a252b9d70fc4d95575f5424263de96fa 333 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 106 286 8.4E-54 T 30-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CL1_0118 a252b9d70fc4d95575f5424263de96fa 333 SUPERFAMILY SSF52283 1 132 2.98E-33 T 30-10-2018 CL1_0118 a252b9d70fc4d95575f5424263de96fa 333 SUPERFAMILY SSF51735 100 287 2.8E-51 T 30-10-2018 IPR036291 NAD(P)-binding domain superfamily CL1_1954 352a180612188177cd95dff970f03cef 202 TIGRFAM TIGR01870 cas_TM1810_Csm2: CRISPR type III-A/MTUBE-associated protein Csm2 100 198 3.3E-18 T 30-10-2018 IPR010149 CRISPR-associated protein, Csm2 Type III-A CL1_1954 352a180612188177cd95dff970f03cef 202 Pfam PF03750 Csm2 Type III-A 88 199 2.6E-17 T 30-10-2018 IPR010149 CRISPR-associated protein, Csm2 Type III-A CL1_1249 73c724261cdfb8566c3876c766cab2be 185 Gene3D G3DSA:3.40.920.10 1 182 5.3E-71 T 30-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 CL1_1249 73c724261cdfb8566c3876c766cab2be 185 SUPERFAMILY SSF53323 1 179 8.24E-56 T 30-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 CL1_1249 73c724261cdfb8566c3876c766cab2be 185 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 10 177 1.1E-41 T 30-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 CL1_1249 73c724261cdfb8566c3876c766cab2be 185 TIGRFAM TIGR02175 PorC_KorC: 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate family 1 180 7.9E-79 T 30-10-2018 IPR011894 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate GO:0016625|GO:0055114 CL1_1079 8200fb737973aa278e71108755c7cedf 155 Pfam PF13091 PLD-like domain 28 145 2.1E-18 T 30-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 CL1_1079 8200fb737973aa278e71108755c7cedf 155 Gene3D G3DSA:3.30.870.10 2 152 9.0E-22 T 30-10-2018 CL1_1079 8200fb737973aa278e71108755c7cedf 155 SUPERFAMILY SSF56024 21 147 5.3E-21 T 30-10-2018 CL1_0231 61638fe4e1d7a57a0e5cbe0d696b2d59 85 Gene3D G3DSA:3.30.310.50 2 85 4.8E-25 T 30-10-2018 CL1_0231 61638fe4e1d7a57a0e5cbe0d696b2d59 85 Pfam PF09341 Transcription factor Pcc1 13 83 8.6E-13 T 30-10-2018 IPR015419 CTAG/Pcc1 family CL1_1425 b052a8c612f2621c4c43fd979498161f 157 PIRSF PIRSF005216 2 157 2.8E-47 T 30-10-2018 IPR002724 Pyruvoyl-dependent arginine decarboxylase GO:0006527|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 CL1_1425 b052a8c612f2621c4c43fd979498161f 157 TIGRFAM TIGR00286 TIGR00286: arginine decarboxylase, pyruvoyl-dependent 6 153 5.4E-39 T 30-10-2018 IPR002724 Pyruvoyl-dependent arginine decarboxylase GO:0006527|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 CL1_1425 b052a8c612f2621c4c43fd979498161f 157 Hamap MF_01404 Pyruvoyl-dependent arginine decarboxylase [pdaD]. 1 157 47.106 T 30-10-2018 IPR002724 Pyruvoyl-dependent arginine decarboxylase GO:0006527|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 CL1_1425 b052a8c612f2621c4c43fd979498161f 157 ProDom PD010449 DECARBOXYLASE PYRUVOYL-DEPENDENT ARGININE SUBUNIT ALPHA CONTAINS: BETA PVLARGDC LYA DECARBOX 6 141 3.0E-70 T 30-10-2018 IPR002724 Pyruvoyl-dependent arginine decarboxylase GO:0006527|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 CL1_1425 b052a8c612f2621c4c43fd979498161f 157 Gene3D G3DSA:3.50.20.10 44 155 1.4E-34 T 30-10-2018 IPR016105 Pyruvoyl-dependent histidine/arginine decarboxylase, 3-layer sandwich domain GO:0006520|GO:0016831 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 CL1_1425 b052a8c612f2621c4c43fd979498161f 157 Pfam PF01862 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) 5 154 1.5E-40 T 30-10-2018 IPR002724 Pyruvoyl-dependent arginine decarboxylase GO:0006527|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 CL1_1425 b052a8c612f2621c4c43fd979498161f 157 Gene3D G3DSA:3.30.60.30 1 43 3.4E-18 T 30-10-2018 CL1_1425 b052a8c612f2621c4c43fd979498161f 157 SUPERFAMILY SSF56271 2 155 1.6E-46 T 30-10-2018 IPR016104 Pyruvoyl-dependent histidine/arginine decarboxylase GO:0006520|GO:0016831 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 CL1_0283 59afe05290627e3a270f5c44808c8450 98 Gene3D G3DSA:2.30.30.70 2 97 2.6E-36 T 30-10-2018 IPR036948 Ribosomal protein L21 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0283 59afe05290627e3a270f5c44808c8450 98 Pfam PF01157 Ribosomal protein L21e 6 95 5.7E-32 T 30-10-2018 IPR001147 Ribosomal protein L21e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0283 59afe05290627e3a270f5c44808c8450 98 SUPERFAMILY SSF50104 6 96 3.91E-31 T 30-10-2018 IPR008991 Translation protein SH3-like domain superfamily CL1_0283 59afe05290627e3a270f5c44808c8450 98 ProSitePatterns PS01171 Ribosomal protein L21e signature. 38 63 - T 30-10-2018 IPR018259 Ribosomal protein L21e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0283 59afe05290627e3a270f5c44808c8450 98 Hamap MF_00369 50S ribosomal protein L21e [rpl21e]. 3 97 30.155 T 30-10-2018 IPR022856 Ribosomal protein L21e, archaeal CL1_0679 36ed6c9c621250df61d2cd913e849c8b 635 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 610 621 - T 30-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CL1_0679 36ed6c9c621250df61d2cd913e849c8b 635 SUPERFAMILY SSF52518 375 560 1.82E-36 T 30-10-2018 IPR029061 Thiamin diphosphate-binding fold CL1_0679 36ed6c9c621250df61d2cd913e849c8b 635 Gene3D G3DSA:3.40.50.970 410 571 1.8E-23 T 30-10-2018 CL1_0679 36ed6c9c621250df61d2cd913e849c8b 635 PIRSF PIRSF006439 11 632 9.4E-218 T 30-10-2018 IPR017721 Indolepyruvate ferredoxin oxidoreductase, alpha subunit GO:0043805|GO:0055114 CL1_0679 36ed6c9c621250df61d2cd913e849c8b 635 SUPERFAMILY SSF52922 247 327 1.37E-7 T 30-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 CL1_0679 36ed6c9c621250df61d2cd913e849c8b 635 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 412 553 1.1E-31 T 30-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CL1_0679 36ed6c9c621250df61d2cd913e849c8b 635 SUPERFAMILY SSF54862 563 628 1.82E-14 T 30-10-2018 CL1_0679 36ed6c9c621250df61d2cd913e849c8b 635 Gene3D G3DSA:3.40.50.970 6 198 8.9E-56 T 30-10-2018 CL1_0679 36ed6c9c621250df61d2cd913e849c8b 635 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 33 214 3.5E-15 T 30-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 CL1_0679 36ed6c9c621250df61d2cd913e849c8b 635 TIGRFAM TIGR03336 IOR_alpha: indolepyruvate ferredoxin oxidoreductase, alpha subunit 21 625 3.8E-218 T 30-10-2018 IPR017721 Indolepyruvate ferredoxin oxidoreductase, alpha subunit GO:0043805|GO:0055114 CL1_0679 36ed6c9c621250df61d2cd913e849c8b 635 SUPERFAMILY SSF52518 20 251 3.41E-58 T 30-10-2018 IPR029061 Thiamin diphosphate-binding fold CL1_0679 36ed6c9c621250df61d2cd913e849c8b 635 Gene3D G3DSA:3.30.70.20 572 635 1.8E-11 T 30-10-2018 CL1_0679 36ed6c9c621250df61d2cd913e849c8b 635 Pfam PF00037 4Fe-4S binding domain 604 626 2.0E-6 T 30-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CL1_1614 6205e3d4db3d179db5e14a5af5a46c59 220 Pfam PF02616 Segregation and condensation protein ScpA 18 162 3.0E-14 T 30-10-2018 IPR003768 Segregation and condensation protein A CL1_1614 6205e3d4db3d179db5e14a5af5a46c59 220 Gene3D G3DSA:1.10.10.580 147 216 3.7E-33 T 30-10-2018 IPR023093 ScpA-like, C-terminal CL1_1474 3b44ccc97168db3341ee893706b83bba 382 SUPERFAMILY SSF51735 1 378 2.36E-73 T 30-10-2018 IPR036291 NAD(P)-binding domain superfamily CL1_1474 3b44ccc97168db3341ee893706b83bba 382 Pfam PF07994 Myo-inositol-1-phosphate synthase 120 211 5.8E-9 T 30-10-2018 IPR002587 Myo-inositol-1-phosphate synthase GO:0004512|GO:0006021|GO:0008654 KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 CL1_1474 3b44ccc97168db3341ee893706b83bba 382 PIRSF PIRSF015578 1 379 1.1E-95 T 30-10-2018 IPR002587 Myo-inositol-1-phosphate synthase GO:0004512|GO:0006021|GO:0008654 KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 CL1_1474 3b44ccc97168db3341ee893706b83bba 382 Pfam PF01658 Myo-inositol-1-phosphate synthase 212 317 5.5E-20 T 30-10-2018 IPR013021 Myo-inositol-1-phosphate synthase, GAPDH-like KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 CL1_1474 3b44ccc97168db3341ee893706b83bba 382 Gene3D G3DSA:3.40.50.720 3 354 7.8E-133 T 30-10-2018 CL1_1474 3b44ccc97168db3341ee893706b83bba 382 SUPERFAMILY SSF55347 211 316 2.35E-28 T 30-10-2018 CL1_1474 3b44ccc97168db3341ee893706b83bba 382 Gene3D G3DSA:3.30.360.10 216 319 7.8E-133 T 30-10-2018 CL1_0390 771f5f8c5e7cb0230f5262917f21e127 199 Pfam PF08745 PINc domain ribonuclease 2 190 1.5E-65 T 30-10-2018 IPR014856 PIN-domain ribonuclease CL1_0390 771f5f8c5e7cb0230f5262917f21e127 199 Hamap MF_01078 UPF0278 protein . 1 193 30.18 T 30-10-2018 IPR014856 PIN-domain ribonuclease CL1_0390 771f5f8c5e7cb0230f5262917f21e127 199 TIGRFAM TIGR03875 RNA_lig_partner: RNA ligase partner, MJ_0950 family 2 189 1.4E-70 T 30-10-2018 IPR014856 PIN-domain ribonuclease CL1_0390 771f5f8c5e7cb0230f5262917f21e127 199 SUPERFAMILY SSF88723 71 187 1.18E-7 T 30-10-2018 IPR029060 PIN-like domain superfamily CL1_1093 2c246efd466d9b9cfdc83d9865dfdc27 172 Gene3D G3DSA:3.30.930.10 1 170 2.6E-64 T 30-10-2018 CL1_1093 2c246efd466d9b9cfdc83d9865dfdc27 172 Pfam PF11447 Protein of unknown function (DUF3201) 8 158 3.5E-66 T 30-10-2018 IPR024505 Protein of unknown function DUF3201 CL1_1093 2c246efd466d9b9cfdc83d9865dfdc27 172 SUPERFAMILY SSF142913 3 170 8.63E-52 T 30-10-2018 CL1_0812 d73d001fe925b7736ad4c3cf8b375479 264 ProDom PD359573 MEMBRANE TRANSMEMBRANE AF2132 PROTEIN 1 231 3.0E-60 T 30-10-2018 CL1_1466 584379b41ab67ca3a27eacf75e18de6b 63 Pfam PF01402 Ribbon-helix-helix protein, copG family 7 45 3.9E-9 T 30-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 CL1_1466 584379b41ab67ca3a27eacf75e18de6b 63 SUPERFAMILY SSF47598 3 46 1.5E-12 T 30-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 CL1_1466 584379b41ab67ca3a27eacf75e18de6b 63 Gene3D G3DSA:1.10.1220.10 11 46 2.2E-10 T 30-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CL1_1239 b5bffd9392678c4245f1b627c7441eb6 253 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 30-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CL1_1239 b5bffd9392678c4245f1b627c7441eb6 253 SUPERFAMILY SSF52540 4 221 3.76E-62 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_1239 b5bffd9392678c4245f1b627c7441eb6 253 Gene3D G3DSA:3.40.50.300 1 241 6.5E-69 T 30-10-2018 CL1_1239 b5bffd9392678c4245f1b627c7441eb6 253 Pfam PF00005 ABC transporter 19 163 1.9E-28 T 30-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CL1_1239 b5bffd9392678c4245f1b627c7441eb6 253 SMART SM00382 28 211 3.1E-16 T 30-10-2018 IPR003593 AAA+ ATPase domain CL1_0436 e7818cd2cbdc272b27232e225b4a9471 448 Hamap MF_00712 Probable glycine dehydrogenase (decarboxylating) subunit 1 [gcvPA]. 3 447 47.713 T 30-10-2018 IPR023010 Probable glycine dehydrogenase (decarboxylating) subunit 1 GO:0004375|GO:0009116 KEGG: 00260+1.4.4.2 CL1_0436 e7818cd2cbdc272b27232e225b4a9471 448 PIRSF PIRSF006815 3 448 8.4E-157 T 30-10-2018 IPR023010 Probable glycine dehydrogenase (decarboxylating) subunit 1 GO:0004375|GO:0009116 KEGG: 00260+1.4.4.2 CL1_0436 e7818cd2cbdc272b27232e225b4a9471 448 Pfam PF02347 Glycine cleavage system P-protein 3 444 5.0E-121 T 30-10-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 CL1_0436 e7818cd2cbdc272b27232e225b4a9471 448 Gene3D G3DSA:3.40.640.10 81 351 3.2E-148 T 30-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 CL1_0436 e7818cd2cbdc272b27232e225b4a9471 448 Gene3D G3DSA:3.90.1150.10 70 444 3.2E-148 T 30-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 CL1_0436 e7818cd2cbdc272b27232e225b4a9471 448 SUPERFAMILY SSF53383 3 447 2.26E-104 T 30-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase CL1_0817 28f42d4937a42cd1c90687b4024c9ae7 174 SUPERFAMILY SSF102114 5 92 1.1E-5 T 30-10-2018 CL1_1076 ab3b20c23a167a1480e611cfe0c0446f 108 SUPERFAMILY SSF110857 1 91 1.57E-20 T 30-10-2018 IPR036568 Gamma-glutamyl cyclotransferase-like superfamily CL1_1076 ab3b20c23a167a1480e611cfe0c0446f 108 Pfam PF06094 Gamma-glutamyl cyclotransferase, AIG2-like 5 82 2.4E-11 T 30-10-2018 IPR009288 Gamma-glutamylcyclotransferase, AIG2-like CL1_1076 ab3b20c23a167a1480e611cfe0c0446f 108 Gene3D G3DSA:3.10.490.10 1 108 1.8E-34 T 30-10-2018 CL1_1120 3dc998a3614a53939d51fd83a462a48f 94 SUPERFAMILY SSF111057 4 76 9.81E-24 T 30-10-2018 IPR036216 Hypothetical protein UCP004604 superfamily CL1_1120 3dc998a3614a53939d51fd83a462a48f 94 Gene3D G3DSA:3.30.2320.10 2 77 1.5E-22 T 30-10-2018 CL1_1120 3dc998a3614a53939d51fd83a462a48f 94 PIRSF PIRSF004604 1 93 2.7E-29 T 30-10-2018 IPR014418 Uncharacterised conserved protein UCP004604 CL1_1120 3dc998a3614a53939d51fd83a462a48f 94 Pfam PF08967 Domain of unknown function (DUF1884) 3 78 2.7E-23 T 30-10-2018 IPR014418 Uncharacterised conserved protein UCP004604 CL1_1120 3dc998a3614a53939d51fd83a462a48f 94 ProDom PD029791 ORF 3'REGION GAP PF1875 PF0899 PH1831 B PHS036 6 76 3.0E-20 T 30-10-2018 IPR014418 Uncharacterised conserved protein UCP004604 CL1_1974 4c2ba8075d5d19ae96e59b8881aab3f7 152 Gene3D G3DSA:3.40.50.1010 6 142 1.3E-10 T 30-10-2018 CL1_1974 4c2ba8075d5d19ae96e59b8881aab3f7 152 Pfam PF01850 PIN domain 6 141 2.9E-12 T 30-10-2018 IPR002716 PIN domain CL1_1974 4c2ba8075d5d19ae96e59b8881aab3f7 152 SUPERFAMILY SSF88723 6 145 2.81E-17 T 30-10-2018 IPR029060 PIN-like domain superfamily CL1_1554 42ed42e2b6d9078cbfa4d9c330d2e05a 243 Gene3D G3DSA:1.20.1260.10 66 239 5.4E-73 T 30-10-2018 IPR012347 Ferritin-like CL1_1554 42ed42e2b6d9078cbfa4d9c330d2e05a 243 Pfam PF09968 Uncharacterized protein domain (DUF2202) 71 231 5.6E-66 T 30-10-2018 IPR019243 Domain of unknown function DUF2202 CL1_1554 42ed42e2b6d9078cbfa4d9c330d2e05a 243 SUPERFAMILY SSF47240 72 210 2.03E-10 T 30-10-2018 IPR009078 Ferritin-like superfamily CL1_0327 7fe19759c2c60ecec036898b336f2d44 151 Gene3D G3DSA:3.40.1600.10 1 148 1.7E-64 T 30-10-2018 IPR036807 PH1570-like superfamily CL1_0327 7fe19759c2c60ecec036898b336f2d44 151 SUPERFAMILY SSF159902 1 147 4.05E-63 T 30-10-2018 CL1_0327 7fe19759c2c60ecec036898b336f2d44 151 Pfam PF09638 Ph1570 protein 1 147 5.7E-69 T 30-10-2018 IPR023110 PH1570-like domain CL1_1266 ab54ad7fee9a7eca2d744de440c0de98 642 SUPERFAMILY SSF54211 49 230 4.93E-25 T 30-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CL1_1266 ab54ad7fee9a7eca2d744de440c0de98 642 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 69 179 1.5E-12 T 30-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 CL1_1266 ab54ad7fee9a7eca2d744de440c0de98 642 Gene3D G3DSA:3.30.230.10 32 225 1.2E-28 T 30-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CL1_1684 b1b0d061b19350f047dbf06e5d6055be 197 Gene3D G3DSA:2.30.110.10 5 116 1.1E-9 T 30-10-2018 IPR012349 FMN-binding split barrel GO:0048037 CL1_1684 b1b0d061b19350f047dbf06e5d6055be 197 SUPERFAMILY SSF50475 5 187 7.85E-32 T 30-10-2018 CL1_1684 b1b0d061b19350f047dbf06e5d6055be 197 PIRSF PIRSF018747 1 195 6.0E-47 T 30-10-2018 IPR016733 Uncharacterised conserved protein UCP018747 CL1_1684 b1b0d061b19350f047dbf06e5d6055be 197 Pfam PF04289 Protein of unknown function (DUF447) 13 189 8.2E-26 T 30-10-2018 IPR007386 Protein of unknown function DUF447 CL1_0443 5bb2a052cd1ed7f226248409686e736f 102 Pfam PF01248 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family 7 95 6.3E-19 T 30-10-2018 IPR004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45 CL1_0443 5bb2a052cd1ed7f226248409686e736f 102 SUPERFAMILY SSF55315 3 97 2.21E-27 T 30-10-2018 IPR029064 50S ribosomal protein L30e-like CL1_0443 5bb2a052cd1ed7f226248409686e736f 102 ProSitePatterns PS00993 Ribosomal protein L30e signature 2. 70 90 - T 30-10-2018 IPR022991 Ribosomal protein L30e, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0443 5bb2a052cd1ed7f226248409686e736f 102 ProSitePatterns PS00709 Ribosomal protein L30e signature 1. 14 38 - T 30-10-2018 IPR022991 Ribosomal protein L30e, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0443 5bb2a052cd1ed7f226248409686e736f 102 Gene3D G3DSA:3.30.1330.30 1 101 7.3E-39 T 30-10-2018 IPR029064 50S ribosomal protein L30e-like CL1_0443 5bb2a052cd1ed7f226248409686e736f 102 Hamap MF_00481 50S ribosomal protein L30e [rpl30e]. 2 99 29.962 T 30-10-2018 IPR000231 Ribosomal protein L30e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0552 a4737d9e84d75a5d850a4e68bd5f7da7 214 ProDom PD016938 P COMPONENT RIBONUCLEASE RNASE HYDROLASE PROCESSING TRNA SUBUNIT SIMILAR P/RNASE 102 194 2.0E-40 T 30-10-2018 CL1_0552 a4737d9e84d75a5d850a4e68bd5f7da7 214 Pfam PF01876 RNase P subunit p30 8 194 1.2E-33 T 30-10-2018 IPR002738 RNase P subunit p30 GO:0004540|GO:0008033 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CL1_0552 a4737d9e84d75a5d850a4e68bd5f7da7 214 Gene3D G3DSA:3.20.20.140 1 204 6.6E-93 T 30-10-2018 CL1_0552 a4737d9e84d75a5d850a4e68bd5f7da7 214 SUPERFAMILY SSF89550 4 202 1.26E-33 T 30-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CL1_0552 a4737d9e84d75a5d850a4e68bd5f7da7 214 Hamap MF_00756 Ribonuclease P protein component 3 [rnp3]. 1 207 22.275 T 30-10-2018 IPR023539 Ribonuclease P, protein component 3, archaeal GO:0001682|GO:0004526 CL1_1159 5d96d2b39ef04c50572ec5eda9aba07f 224 SUPERFAMILY SSF109755 25 221 9.1E-18 T 30-10-2018 CL1_1159 5d96d2b39ef04c50572ec5eda9aba07f 224 TIGRFAM TIGR00153 TIGR00153: TIGR00153 family protein 5 222 6.0E-37 T 30-10-2018 IPR002727 Protein of unknown function DUF47 CL1_1159 5d96d2b39ef04c50572ec5eda9aba07f 224 Gene3D G3DSA:1.20.58.220 1 224 1.4E-47 T 30-10-2018 IPR038078 PhoU-like domain superfamily CL1_1159 5d96d2b39ef04c50572ec5eda9aba07f 224 Pfam PF01865 Protein of unknown function DUF47 6 222 3.2E-44 T 30-10-2018 IPR018445 Putative phosphate transport regulator CL1_0925 0433f8ec32570918c3b96a443733dae6 321 SUPERFAMILY SSF161098 85 290 3.53E-9 T 30-10-2018 IPR035906 MetI-like superfamily CL1_0925 0433f8ec32570918c3b96a443733dae6 321 Gene3D G3DSA:1.10.3720.10 83 307 1.5E-8 T 30-10-2018 IPR035906 MetI-like superfamily CL1_0925 0433f8ec32570918c3b96a443733dae6 321 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 103 315 5.6E-20 T 30-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 CL1_0337 5be7c85334875c426fe6c467a321ea33 464 SUPERFAMILY SSF52540 25 209 2.23E-17 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_0337 5be7c85334875c426fe6c467a321ea33 464 SMART SM00490 328 406 1.5E-13 T 30-10-2018 IPR001650 Helicase, C-terminal CL1_0337 5be7c85334875c426fe6c467a321ea33 464 Pfam PF04851 Type III restriction enzyme, res subunit 92 231 9.5E-18 T 30-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 CL1_0337 5be7c85334875c426fe6c467a321ea33 464 Gene3D G3DSA:3.40.50.300 274 458 1.5E-33 T 30-10-2018 CL1_0337 5be7c85334875c426fe6c467a321ea33 464 Gene3D G3DSA:3.40.50.300 84 261 7.8E-35 T 30-10-2018 CL1_0337 5be7c85334875c426fe6c467a321ea33 464 SUPERFAMILY SSF52540 136 420 1.22E-34 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_0337 5be7c85334875c426fe6c467a321ea33 464 SMART SM00487 91 272 1.0E-27 T 30-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CL1_0337 5be7c85334875c426fe6c467a321ea33 464 Pfam PF00271 Helicase conserved C-terminal domain 308 404 1.2E-11 T 30-10-2018 IPR001650 Helicase, C-terminal CL1_0021 6c7b4b0b11ffd8e9ce638dd2b34eddc2 409 Gene3D G3DSA:3.40.50.2300 36 311 5.6E-90 T 30-10-2018 CL1_0021 6c7b4b0b11ffd8e9ce638dd2b34eddc2 409 Gene3D G3DSA:3.40.50.2300 137 323 5.6E-90 T 30-10-2018 CL1_0021 6c7b4b0b11ffd8e9ce638dd2b34eddc2 409 SUPERFAMILY SSF53822 48 296 1.3E-8 T 30-10-2018 IPR028082 Periplasmic binding protein-like I CL1_0021 6c7b4b0b11ffd8e9ce638dd2b34eddc2 409 Pfam PF02608 ABC transporter substrate-binding protein PnrA-like 37 329 3.4E-55 T 30-10-2018 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 CL1_1699 a03ae1cbff2c8a402c3b4cdcc552b5ee 199 SUPERFAMILY SSF53448 18 144 5.63E-9 T 30-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases CL1_1699 a03ae1cbff2c8a402c3b4cdcc552b5ee 199 Gene3D G3DSA:3.90.550.10 16 198 6.4E-12 T 30-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases CL1_1699 a03ae1cbff2c8a402c3b4cdcc552b5ee 199 Pfam PF12804 MobA-like NTP transferase domain 18 150 4.2E-6 T 30-10-2018 IPR025877 MobA-like NTP transferase CL1_1791 076140d2718b325d46f4facb61eea842 295 SUPERFAMILY SSF54862 55 121 1.93E-16 T 30-10-2018 CL1_1791 076140d2718b325d46f4facb61eea842 295 Pfam PF14697 4Fe-4S dicluster domain 64 117 3.7E-10 T 30-10-2018 CL1_1791 076140d2718b325d46f4facb61eea842 295 SUPERFAMILY SSF52540 2 293 2.07E-38 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_1791 076140d2718b325d46f4facb61eea842 295 Gene3D G3DSA:3.30.70.20 69 115 2.0E-10 T 30-10-2018 CL1_1791 076140d2718b325d46f4facb61eea842 295 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 100 111 - T 30-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CL1_1791 076140d2718b325d46f4facb61eea842 295 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 3 264 4.5E-23 T 30-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain CL1_1791 076140d2718b325d46f4facb61eea842 295 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 71 82 - T 30-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CL1_1233 92eaca1dddbd1ca487fe9b0c8a3ecb98 296 Gene3D G3DSA:3.40.1190.20 1 284 2.0E-63 T 30-10-2018 IPR029056 Ribokinase-like CL1_1233 92eaca1dddbd1ca487fe9b0c8a3ecb98 296 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 228 241 - T 30-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 CL1_1233 92eaca1dddbd1ca487fe9b0c8a3ecb98 296 PRINTS PR00990 Ribokinase signature 35 54 1.8E-8 T 30-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CL1_1233 92eaca1dddbd1ca487fe9b0c8a3ecb98 296 PRINTS PR00990 Ribokinase signature 105 118 1.8E-8 T 30-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CL1_1233 92eaca1dddbd1ca487fe9b0c8a3ecb98 296 PRINTS PR00990 Ribokinase signature 166 181 1.8E-8 T 30-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CL1_1233 92eaca1dddbd1ca487fe9b0c8a3ecb98 296 PRINTS PR00990 Ribokinase signature 198 209 1.8E-8 T 30-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CL1_1233 92eaca1dddbd1ca487fe9b0c8a3ecb98 296 PRINTS PR00990 Ribokinase signature 8 29 1.8E-8 T 30-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CL1_1233 92eaca1dddbd1ca487fe9b0c8a3ecb98 296 Pfam PF00294 pfkB family carbohydrate kinase 5 273 7.9E-42 T 30-10-2018 IPR011611 Carbohydrate kinase PfkB CL1_1233 92eaca1dddbd1ca487fe9b0c8a3ecb98 296 SUPERFAMILY SSF53613 1 279 3.74E-65 T 30-10-2018 IPR029056 Ribokinase-like CL1_1982 af467da0870d5261aa9af22bed1f7f5b 158 SUPERFAMILY SSF55040 12 155 1.7E-51 T 30-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CL1_1982 af467da0870d5261aa9af22bed1f7f5b 158 Hamap MF_01224_A Cyclic pyranopterin monophosphate synthase [moaC]. 9 154 39.457 T 30-10-2018 IPR023047 Probable cyclic pyranopterin monophosphate synthase accessory protein, archaea KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823 CL1_1982 af467da0870d5261aa9af22bed1f7f5b 158 TIGRFAM TIGR00581 moaC: molybdenum cofactor biosynthesis protein C 4 138 3.9E-54 T 30-10-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CL1_1982 af467da0870d5261aa9af22bed1f7f5b 158 Gene3D G3DSA:3.30.70.640 1 158 3.0E-68 T 30-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CL1_1982 af467da0870d5261aa9af22bed1f7f5b 158 Pfam PF01967 MoaC family 14 154 5.2E-52 T 30-10-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CL1_0914 537b7da150433e061db2093e32e90c1f 319 SMART SM00382 34 240 6.8E-10 T 30-10-2018 IPR003593 AAA+ ATPase domain CL1_0914 537b7da150433e061db2093e32e90c1f 319 Pfam PF00005 ABC transporter 25 182 3.1E-28 T 30-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CL1_0914 537b7da150433e061db2093e32e90c1f 319 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 232 318 1.3E-30 T 30-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CL1_0914 537b7da150433e061db2093e32e90c1f 319 Gene3D G3DSA:3.40.50.300 2 319 1.1E-104 T 30-10-2018 CL1_0914 537b7da150433e061db2093e32e90c1f 319 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 30-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CL1_0914 537b7da150433e061db2093e32e90c1f 319 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 234 298 4.1E-20 T 30-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CL1_0914 537b7da150433e061db2093e32e90c1f 319 SUPERFAMILY SSF52540 5 254 1.24E-68 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_1350 e25ef3f0ad8d2220efdb114fb608475f 589 Gene3D G3DSA:1.50.10.20 25 127 8.3E-11 T 30-10-2018 CL1_1350 e25ef3f0ad8d2220efdb114fb608475f 589 SUPERFAMILY SSF48239 29 234 1.61E-18 T 30-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid CL1_1350 e25ef3f0ad8d2220efdb114fb608475f 589 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 554 586 1.8E-4 T 30-10-2018 CL1_1350 e25ef3f0ad8d2220efdb114fb608475f 589 SUPERFAMILY SSF48239 403 486 1.37E-11 T 30-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid CL1_1796 130d6909daab1c099a8c8adf5c6fc68d 339 SUPERFAMILY SSF52540 1 335 8.71E-108 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_1796 130d6909daab1c099a8c8adf5c6fc68d 339 Gene3D G3DSA:3.40.440.10 1 339 2.8E-138 T 30-10-2018 CL1_1796 130d6909daab1c099a8c8adf5c6fc68d 339 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 339 97.688 T 30-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CL1_1796 130d6909daab1c099a8c8adf5c6fc68d 339 SMART SM00788 3 334 1.3E-155 T 30-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CL1_1796 130d6909daab1c099a8c8adf5c6fc68d 339 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 10 17 - T 30-10-2018 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CL1_1796 130d6909daab1c099a8c8adf5c6fc68d 339 Pfam PF00709 Adenylosuccinate synthetase 149 289 2.9E-44 T 30-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CL1_1796 130d6909daab1c099a8c8adf5c6fc68d 339 Pfam PF00709 Adenylosuccinate synthetase 5 143 1.2E-36 T 30-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CL1_1796 130d6909daab1c099a8c8adf5c6fc68d 339 Pfam PF00709 Adenylosuccinate synthetase 291 333 6.0E-6 T 30-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CL1_0737 2f1d40a2f076f514a289e7fb84e09aaf 204 SUPERFAMILY SSF54001 43 201 7.85E-26 T 30-10-2018 IPR038765 Papain-like cysteine peptidase superfamily CL1_0737 2f1d40a2f076f514a289e7fb84e09aaf 204 Pfam PF05708 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family 44 200 4.5E-38 T 30-10-2018 IPR024453 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family CL1_0737 2f1d40a2f076f514a289e7fb84e09aaf 204 Gene3D G3DSA:3.90.1720.10 43 202 1.9E-16 T 30-10-2018 CL1_1365 3a70aef80c4205388bd4e4155817ec9c 301 SUPERFAMILY SSF51395 1 298 5.66E-85 T 30-10-2018 CL1_1365 3a70aef80c4205388bd4e4155817ec9c 301 TIGRFAM TIGR01037 pyrD_sub1_fam: dihydroorotate dehydrogenase family protein 4 298 8.1E-131 T 30-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 CL1_1365 3a70aef80c4205388bd4e4155817ec9c 301 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 235 255 - T 30-10-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 CL1_1365 3a70aef80c4205388bd4e4155817ec9c 301 PIRSF PIRSF000164 1 300 1.6E-89 T 30-10-2018 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 CL1_1365 3a70aef80c4205388bd4e4155817ec9c 301 Pfam PF01180 Dihydroorotate dehydrogenase 4 282 1.9E-64 T 30-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 CL1_1365 3a70aef80c4205388bd4e4155817ec9c 301 Gene3D G3DSA:2.30.26.10 55 212 8.1E-94 T 30-10-2018 IPR023359 Dihydroorotate dehydrogenase A, chain A, domain 2 CL1_1365 3a70aef80c4205388bd4e4155817ec9c 301 ProSitePatterns PS00911 Dihydroorotate dehydrogenase signature 1. 40 59 - T 30-10-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 CL1_1365 3a70aef80c4205388bd4e4155817ec9c 301 Gene3D G3DSA:3.20.20.70 12 289 8.1E-94 T 30-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CL1_1365 3a70aef80c4205388bd4e4155817ec9c 301 Hamap MF_00224 Dihydroorotate dehydrogenase [pyrD]. 4 298 36.829 T 30-10-2018 IPR024920 Dihydroorotate dehydrogenase, class 1 GO:0004152|GO:0005737|GO:0006221 CL1_1529 40b0c8d749fd945d996cbd3a6198a209 401 Pfam PF06819 Archaeal Peptidase A24 C-terminal Domain 257 365 1.2E-28 T 30-10-2018 IPR009639 Peptidase A24A-predicted, C-terminal archaea CL1_1529 40b0c8d749fd945d996cbd3a6198a209 401 Gene3D G3DSA:1.20.120.1220 52 172 1.0E-13 T 30-10-2018 CL1_0975 ab672c033976c9bf033853df333a75de 229 Pfam PF13419 Haloacid dehalogenase-like hydrolase 3 194 2.9E-18 T 30-10-2018 CL1_0975 ab672c033976c9bf033853df333a75de 229 SUPERFAMILY SSF56784 3 222 3.34E-36 T 30-10-2018 IPR036412 HAD-like superfamily CL1_0975 ab672c033976c9bf033853df333a75de 229 Gene3D G3DSA:3.40.50.1000 3 216 5.9E-35 T 30-10-2018 IPR023214 HAD superfamily CL1_0975 ab672c033976c9bf033853df333a75de 229 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 109 188 1.4E-10 T 30-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 CL1_0975 ab672c033976c9bf033853df333a75de 229 Gene3D G3DSA:1.10.150.520 14 96 5.9E-35 T 30-10-2018 CL1_1427 583973d1a768b0010629e6f5a896064e 155 Gene3D G3DSA:3.30.70.260 77 152 1.2E-9 T 30-10-2018 CL1_1427 583973d1a768b0010629e6f5a896064e 155 SUPERFAMILY SSF55021 79 150 3.56E-12 T 30-10-2018 CL1_1427 583973d1a768b0010629e6f5a896064e 155 Pfam PF01842 ACT domain 80 144 3.7E-12 T 30-10-2018 IPR002912 ACT domain CL1_1202 93926bf2628a4083141c11472afb195a 417 SUPERFAMILY SSF53335 60 413 7.57E-72 T 30-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CL1_1202 93926bf2628a4083141c11472afb195a 417 Gene3D G3DSA:3.40.1350.30 112 257 5.7E-119 T 30-10-2018 CL1_1202 93926bf2628a4083141c11472afb195a 417 Gene3D G3DSA:3.40.50.150 73 410 5.7E-119 T 30-10-2018 CL1_1202 93926bf2628a4083141c11472afb195a 417 Gene3D G3DSA:2.40.50.140 2 71 1.5E-14 T 30-10-2018 CL1_1202 93926bf2628a4083141c11472afb195a 417 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 398 408 - T 30-10-2018 IPR030391 RNA methyltransferase TrmA, conserved site CL1_1202 93926bf2628a4083141c11472afb195a 417 SUPERFAMILY SSF50249 4 58 1.71E-8 T 30-10-2018 IPR012340 Nucleic acid-binding, OB-fold CL1_1202 93926bf2628a4083141c11472afb195a 417 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 8 408 2.6E-85 T 30-10-2018 CL1_1202 93926bf2628a4083141c11472afb195a 417 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 340 414 7.4E-16 T 30-10-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 CL1_1202 93926bf2628a4083141c11472afb195a 417 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 240 324 6.3E-6 T 30-10-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 CL1_1202 93926bf2628a4083141c11472afb195a 417 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 347 378 - T 30-10-2018 IPR030390 RNA methyltransferase TrmA, active site CL1_0168 70037931aa9555db3e6a6b94585996ca 423 Pfam PF02163 Peptidase family M50 310 350 2.6E-7 T 30-10-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 CL1_0629 1db8170a4e54a59e25308d7f4739d7fe 256 Gene3D G3DSA:3.40.1280.10 5 252 1.5E-76 T 30-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CL1_0629 1db8170a4e54a59e25308d7f4739d7fe 256 Pfam PF02598 Putative RNA methyltransferase 5 249 5.1E-52 T 30-10-2018 IPR003750 Putative RNA methyltransferase CL1_0629 1db8170a4e54a59e25308d7f4739d7fe 256 SUPERFAMILY SSF75217 4 254 3.4E-47 T 30-10-2018 IPR029028 Alpha/beta knot methyltransferases CL1_0629 1db8170a4e54a59e25308d7f4739d7fe 256 SUPERFAMILY SSF50249 91 156 1.71E-11 T 30-10-2018 IPR012340 Nucleic acid-binding, OB-fold CL1_0629 1db8170a4e54a59e25308d7f4739d7fe 256 Gene3D G3DSA:2.40.50.140 91 156 1.5E-76 T 30-10-2018 CL1_1601 fe0feab7c63d207730768a3f48edcd86 480 Gene3D G3DSA:3.60.20.10 2 212 7.8E-42 T 30-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CL1_1601 fe0feab7c63d207730768a3f48edcd86 480 SUPERFAMILY SSF52402 218 456 3.77E-57 T 30-10-2018 CL1_1601 fe0feab7c63d207730768a3f48edcd86 480 Pfam PF00733 Asparagine synthase 238 360 2.6E-32 T 30-10-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 CL1_1601 fe0feab7c63d207730768a3f48edcd86 480 Pfam PF00733 Asparagine synthase 364 459 3.8E-20 T 30-10-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 CL1_1601 fe0feab7c63d207730768a3f48edcd86 480 PIRSF PIRSF001589 364 477 1.8E-16 T 30-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 CL1_1601 fe0feab7c63d207730768a3f48edcd86 480 PIRSF PIRSF001589 1 376 8.9E-57 T 30-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 CL1_1601 fe0feab7c63d207730768a3f48edcd86 480 Pfam PF13537 Glutamine amidotransferase domain 61 179 2.1E-24 T 30-10-2018 IPR017932 Glutamine amidotransferase type 2 domain CL1_1601 fe0feab7c63d207730768a3f48edcd86 480 SUPERFAMILY SSF56235 4 204 4.55E-42 T 30-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CL1_1601 fe0feab7c63d207730768a3f48edcd86 480 Gene3D G3DSA:3.40.50.620 215 479 1.8E-73 T 30-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CL1_0708 ec6186154c63ee781f22201356c21050 541 Gene3D G3DSA:1.10.3720.10 289 540 2.2E-55 T 30-10-2018 IPR035906 MetI-like superfamily CL1_0708 ec6186154c63ee781f22201356c21050 541 Gene3D G3DSA:1.10.3720.10 6 265 3.1E-62 T 30-10-2018 IPR035906 MetI-like superfamily CL1_0708 ec6186154c63ee781f22201356c21050 541 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 74 254 3.6E-14 T 30-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 CL1_0708 ec6186154c63ee781f22201356c21050 541 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 371 531 2.0E-13 T 30-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 CL1_0708 ec6186154c63ee781f22201356c21050 541 SUPERFAMILY SSF161098 6 258 1.87E-54 T 30-10-2018 IPR035906 MetI-like superfamily CL1_0708 ec6186154c63ee781f22201356c21050 541 SUPERFAMILY SSF161098 288 536 4.21E-55 T 30-10-2018 IPR035906 MetI-like superfamily CL1_1630 e49e37588becb2b8edccf6420ad247c0 281 SUPERFAMILY SSF117892 54 187 5.89E-47 T 30-10-2018 IPR036013 Band 7/SPFH domain superfamily CL1_1630 e49e37588becb2b8edccf6420ad247c0 281 PRINTS PR00721 Stomatin signature 175 196 1.5E-73 T 30-10-2018 IPR001972 Stomatin family GO:0016020 CL1_1630 e49e37588becb2b8edccf6420ad247c0 281 PRINTS PR00721 Stomatin signature 132 155 1.5E-73 T 30-10-2018 IPR001972 Stomatin family GO:0016020 CL1_1630 e49e37588becb2b8edccf6420ad247c0 281 PRINTS PR00721 Stomatin signature 112 129 1.5E-73 T 30-10-2018 IPR001972 Stomatin family GO:0016020 CL1_1630 e49e37588becb2b8edccf6420ad247c0 281 PRINTS PR00721 Stomatin signature 156 174 1.5E-73 T 30-10-2018 IPR001972 Stomatin family GO:0016020 CL1_1630 e49e37588becb2b8edccf6420ad247c0 281 PRINTS PR00721 Stomatin signature 30 52 1.5E-73 T 30-10-2018 IPR001972 Stomatin family GO:0016020 CL1_1630 e49e37588becb2b8edccf6420ad247c0 281 PRINTS PR00721 Stomatin signature 77 98 1.5E-73 T 30-10-2018 IPR001972 Stomatin family GO:0016020 CL1_1630 e49e37588becb2b8edccf6420ad247c0 281 PRINTS PR00721 Stomatin signature 200 223 1.5E-73 T 30-10-2018 IPR001972 Stomatin family GO:0016020 CL1_1630 e49e37588becb2b8edccf6420ad247c0 281 Gene3D G3DSA:3.30.479.30 51 182 7.0E-52 T 30-10-2018 CL1_1630 e49e37588becb2b8edccf6420ad247c0 281 Pfam PF01145 SPFH domain / Band 7 family 27 197 8.5E-39 T 30-10-2018 IPR001107 Band 7 domain CL1_1630 e49e37588becb2b8edccf6420ad247c0 281 SMART SM00244 23 180 1.7E-70 T 30-10-2018 IPR001107 Band 7 domain CL1_0636 bbff1fde6506faf04d40ed607cd42e35 300 Pfam PF00152 tRNA synthetases class II (D, K and N) 3 292 4.8E-42 T 30-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CL1_0636 bbff1fde6506faf04d40ed607cd42e35 300 Gene3D G3DSA:3.30.930.10 1 299 5.6E-73 T 30-10-2018 CL1_0636 bbff1fde6506faf04d40ed607cd42e35 300 SUPERFAMILY SSF55681 6 295 1.87E-54 T 30-10-2018 CL1_0605 f3a53d8bb800a7a2b18f649b84d6f19c 148 ProSitePatterns PS00475 Ribosomal protein L15 signature. 112 142 - T 30-10-2018 IPR001196 Ribosomal protein L15, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0605 f3a53d8bb800a7a2b18f649b84d6f19c 148 SUPERFAMILY SSF52080 5 147 3.53E-34 T 30-10-2018 IPR036227 Ribosomal L18e/L15P superfamily CL1_0605 f3a53d8bb800a7a2b18f649b84d6f19c 148 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 1 148 14.447 T 30-10-2018 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 CL1_0605 f3a53d8bb800a7a2b18f649b84d6f19c 148 Gene3D G3DSA:4.10.990.10 4 52 1.9E-9 T 30-10-2018 IPR027386 50S ribosomal protein L15, N-terminal CL1_0605 f3a53d8bb800a7a2b18f649b84d6f19c 148 Gene3D G3DSA:3.100.10.10 63 148 1.0E-23 T 30-10-2018 CL1_0605 f3a53d8bb800a7a2b18f649b84d6f19c 148 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 29 146 4.1E-20 T 30-10-2018 IPR021131 Ribosomal protein L18e/L15P CL1_0253 1914d3e354086118b4fd939a3b07eeca 175 Pfam PF06195 Protein of unknown function (DUF996) 23 148 1.2E-27 T 30-10-2018 IPR010397 Protein of unknown function DUF996 CL1_1573 ce597ef8a2f63cc5b9f7d952081755dd 89 ProDom PD006030 RIBOSOMAL 60S L31 RIBONUCLEOPROTEIN L31E 50S L31 SUBUNIT STRAIN PHOSPHORYLATION 27 57 5.0E-10 T 30-10-2018 IPR000054 Ribosomal protein L31e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_1573 ce597ef8a2f63cc5b9f7d952081755dd 89 Hamap MF_00410 50S ribosomal protein L31e [rpl31e]. 3 89 22.176 T 30-10-2018 IPR000054 Ribosomal protein L31e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_1573 ce597ef8a2f63cc5b9f7d952081755dd 89 SUPERFAMILY SSF54575 6 83 1.57E-22 T 30-10-2018 IPR023621 Ribosomal protein L31e domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_1573 ce597ef8a2f63cc5b9f7d952081755dd 89 Gene3D G3DSA:3.10.440.10 2 89 1.6E-25 T 30-10-2018 IPR023621 Ribosomal protein L31e domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_1573 ce597ef8a2f63cc5b9f7d952081755dd 89 ProSitePatterns PS01144 Ribosomal protein L31e signature. 47 61 - T 30-10-2018 IPR020052 Ribosomal protein L31e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_1573 ce597ef8a2f63cc5b9f7d952081755dd 89 SMART SM01380 7 85 3.9E-18 T 30-10-2018 IPR000054 Ribosomal protein L31e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_1573 ce597ef8a2f63cc5b9f7d952081755dd 89 Pfam PF01198 Ribosomal protein L31e 12 79 1.9E-9 T 30-10-2018 IPR000054 Ribosomal protein L31e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_1839 5c888606c0479fd6a5b67a9ed794d720 119 SUPERFAMILY SSF117916 16 59 1.57E-5 T 30-10-2018 IPR034904 Fe-S cluster assembly domain superfamily CL1_1839 5c888606c0479fd6a5b67a9ed794d720 119 Pfam PF01883 Iron-sulfur cluster assembly protein 15 56 3.0E-5 T 30-10-2018 IPR002744 MIP18 family-like CL1_0981 fbb294c0f617da137f87aef115163752 75 SUPERFAMILY SSF47598 7 49 1.1E-6 T 30-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 CL1_0195 4fbe89175a45ca663163913c14952aef 114 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 5 111 1.4E-32 T 30-10-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like CL1_0861 371b536f69a43d7419eec2636123c90b 144 SUPERFAMILY SSF47240 3 143 1.92E-14 T 30-10-2018 IPR009078 Ferritin-like superfamily CL1_0861 371b536f69a43d7419eec2636123c90b 144 Pfam PF02915 Rubrerythrin 30 141 2.6E-11 T 30-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 CL1_0861 371b536f69a43d7419eec2636123c90b 144 Gene3D G3DSA:1.20.1260.10 1 144 5.2E-14 T 30-10-2018 IPR012347 Ferritin-like CL1_2034 38c5e231910864efd69df998752ecf38 114 Gene3D G3DSA:2.60.120.10 10 106 7.7E-23 T 30-10-2018 IPR014710 RmlC-like jelly roll fold CL1_2034 38c5e231910864efd69df998752ecf38 114 Pfam PF07883 Cupin domain 32 100 8.9E-19 T 30-10-2018 IPR013096 Cupin 2, conserved barrel CL1_2034 38c5e231910864efd69df998752ecf38 114 SUPERFAMILY SSF51182 10 104 7.88E-25 T 30-10-2018 IPR011051 RmlC-like cupin domain superfamily CL1_1795 d1eda0035e3e9081708f39a6508a30a0 310 Pfam PF01370 NAD dependent epimerase/dehydratase family 6 236 1.1E-61 T 30-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CL1_1795 d1eda0035e3e9081708f39a6508a30a0 310 Gene3D G3DSA:3.40.50.720 8 289 5.6E-107 T 30-10-2018 CL1_1795 d1eda0035e3e9081708f39a6508a30a0 310 Gene3D G3DSA:3.90.25.10 168 301 5.6E-107 T 30-10-2018 CL1_1795 d1eda0035e3e9081708f39a6508a30a0 310 SUPERFAMILY SSF51735 1 304 4.13E-100 T 30-10-2018 IPR036291 NAD(P)-binding domain superfamily CL1_0736 aa4c652e3abc0a4d535d530fa324f75a 193 Gene3D G3DSA:3.90.1720.10 47 165 9.3E-15 T 30-10-2018 CL1_0736 aa4c652e3abc0a4d535d530fa324f75a 193 Pfam PF05708 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family 41 189 1.5E-26 T 30-10-2018 IPR024453 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family CL1_0736 aa4c652e3abc0a4d535d530fa324f75a 193 SUPERFAMILY SSF54001 38 189 1.9E-28 T 30-10-2018 IPR038765 Papain-like cysteine peptidase superfamily CL1_1421 57c7071ca61346e6bb7389422f382609 379 Gene3D G3DSA:3.40.50.2000 174 361 1.9E-96 T 30-10-2018 CL1_1421 57c7071ca61346e6bb7389422f382609 379 SUPERFAMILY SSF53756 3 376 9.91E-99 T 30-10-2018 CL1_1421 57c7071ca61346e6bb7389422f382609 379 Pfam PF13439 Glycosyltransferase Family 4 9 177 7.2E-29 T 30-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 CL1_1421 57c7071ca61346e6bb7389422f382609 379 Gene3D G3DSA:3.40.50.2000 1 173 1.9E-96 T 30-10-2018 CL1_1421 57c7071ca61346e6bb7389422f382609 379 Pfam PF00534 Glycosyl transferases group 1 193 353 6.9E-48 T 30-10-2018 IPR001296 Glycosyl transferase, family 1 CL1_0585 a8362df54c504c1a5bfcd9a2bb87de67 52 Hamap MF_00788 50S ribosomal protein L40e [rpl40e]. 2 47 19.565 T 30-10-2018 IPR023657 Ribosomal protein L40e, archaeal GO:0003735|GO:0005840|GO:0006412 CL1_0585 a8362df54c504c1a5bfcd9a2bb87de67 52 SMART SM01377 1 46 3.5E-8 T 30-10-2018 IPR001975 Ribosomal protein L40e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 CL1_0585 a8362df54c504c1a5bfcd9a2bb87de67 52 Gene3D G3DSA:2.20.28.70 1 49 1.1E-18 T 30-10-2018 IPR038587 Ribosomal protein L40e superfamily Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 CL1_0585 a8362df54c504c1a5bfcd9a2bb87de67 52 SUPERFAMILY SSF57829 2 46 8.24E-16 T 30-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 CL1_1238 4df83597b7479ceedfd8d690a18463a6 295 ProSitePatterns PS01215 Mrp family signature. 146 162 - T 30-10-2018 IPR000808 Mrp, conserved site GO:0005524 CL1_1238 4df83597b7479ceedfd8d690a18463a6 295 Hamap MF_02040 Iron-sulfur cluster carrier protein. 20 282 37.021 T 30-10-2018 IPR019591 Mrp/NBP35 ATP-binding protein CL1_1238 4df83597b7479ceedfd8d690a18463a6 295 Gene3D G3DSA:3.40.50.300 17 281 9.3E-82 T 30-10-2018 CL1_1238 4df83597b7479ceedfd8d690a18463a6 295 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 31 281 1.8E-96 T 30-10-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 CL1_1238 4df83597b7479ceedfd8d690a18463a6 295 SUPERFAMILY SSF52540 18 266 2.21E-58 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_0490 1fdbe6defd9d779604853e63d329210e 338 Gene3D G3DSA:3.90.650.10 156 338 1.7E-56 T 30-10-2018 IPR036676 PurM-like, C-terminal domain superfamily CL1_0490 1fdbe6defd9d779604853e63d329210e 338 TIGRFAM TIGR02124 hypE: hydrogenase expression/formation protein HypE 4 338 3.5E-122 T 30-10-2018 IPR011854 Carbamoyl dehydratase HypE CL1_0490 1fdbe6defd9d779604853e63d329210e 338 Pfam PF00586 AIR synthase related protein, N-terminal domain 42 151 1.3E-17 T 30-10-2018 IPR016188 PurM-like, N-terminal domain CL1_0490 1fdbe6defd9d779604853e63d329210e 338 Gene3D G3DSA:3.30.1330.10 1 155 5.3E-45 T 30-10-2018 IPR036921 PurM-like, N-terminal domain superfamily CL1_0490 1fdbe6defd9d779604853e63d329210e 338 Pfam PF02769 AIR synthase related protein, C-terminal domain 162 315 3.6E-32 T 30-10-2018 IPR010918 PurM-like, C-terminal domain CL1_0490 1fdbe6defd9d779604853e63d329210e 338 SUPERFAMILY SSF56042 157 332 3.89E-48 T 30-10-2018 IPR036676 PurM-like, C-terminal domain superfamily CL1_0490 1fdbe6defd9d779604853e63d329210e 338 PIRSF PIRSF005644 1 338 7.4E-128 T 30-10-2018 IPR011854 Carbamoyl dehydratase HypE CL1_0490 1fdbe6defd9d779604853e63d329210e 338 SUPERFAMILY SSF55326 6 155 4.45E-33 T 30-10-2018 IPR036921 PurM-like, N-terminal domain superfamily CL1_0300 dc54ccceaa1488d2c3858cdc3b6661bc 345 SUPERFAMILY SSF53187 4 338 1.24E-63 T 30-10-2018 CL1_0300 dc54ccceaa1488d2c3858cdc3b6661bc 345 SUPERFAMILY SSF101821 68 176 3.51E-27 T 30-10-2018 CL1_0300 dc54ccceaa1488d2c3858cdc3b6661bc 345 PIRSF PIRSF001123 1 344 1.6E-101 T 30-10-2018 IPR008007 Peptidase M42 CL1_0300 dc54ccceaa1488d2c3858cdc3b6661bc 345 Gene3D G3DSA:3.40.630.10 7 332 9.1E-131 T 30-10-2018 CL1_0300 dc54ccceaa1488d2c3858cdc3b6661bc 345 Pfam PF05343 M42 glutamyl aminopeptidase 45 329 2.4E-96 T 30-10-2018 IPR008007 Peptidase M42 CL1_0300 dc54ccceaa1488d2c3858cdc3b6661bc 345 Gene3D G3DSA:2.40.30.40 68 160 9.1E-131 T 30-10-2018 IPR023367 Peptidase M42, domain 2 CL1_1994 2852ac375c45f020ea395598fd377235 137 SUPERFAMILY SSF81301 7 90 3.27E-15 T 30-10-2018 CL1_1994 2852ac375c45f020ea395598fd377235 137 Pfam PF01909 Nucleotidyltransferase domain 18 78 2.4E-7 T 30-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 CL1_1994 2852ac375c45f020ea395598fd377235 137 Gene3D G3DSA:3.30.460.10 1 135 8.1E-9 T 30-10-2018 CL1_1609 4e4a66b2049edd18289a1167c646c944 143 SUPERFAMILY SSF52242 5 133 3.14E-49 T 30-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 CL1_1609 4e4a66b2049edd18289a1167c646c944 143 Gene3D G3DSA:3.40.50.280 1 143 1.1E-57 T 30-10-2018 CL1_1609 4e4a66b2049edd18289a1167c646c944 143 TIGRFAM TIGR00640 acid_CoA_mut_C: methylmalonyl-CoA mutase C-terminal domain 6 138 4.4E-60 T 30-10-2018 IPR006159 Methylmalonyl-CoA mutase, C-terminal GO:0016853 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CL1_1609 4e4a66b2049edd18289a1167c646c944 143 Pfam PF02310 B12 binding domain 8 120 1.8E-24 T 30-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CL1_0646 74a101653774643a917a94010849da12 281 SUPERFAMILY SSF51556 1 278 1.23E-32 T 30-10-2018 IPR032466 Metal-dependent hydrolase CL1_0646 74a101653774643a917a94010849da12 281 ProDom PD038341 HYDROLASE COFACTOR MOLYBDENUM BIOSYNTHESIS METAL-DEPENDENT DEOXYRIBONUCLEASE PREDICTED TATD-RELATED TVG0313409 A 114 280 1.0E-83 T 30-10-2018 CL1_0646 74a101653774643a917a94010849da12 281 PIRSF PIRSF004961 1 281 5.2E-123 T 30-10-2018 IPR011589 Protein of unknown function UCP004961 CL1_0646 74a101653774643a917a94010849da12 281 Pfam PF01026 TatD related DNase 5 275 1.8E-31 T 30-10-2018 IPR001130 TatD family GO:0016788 CL1_0646 74a101653774643a917a94010849da12 281 Gene3D G3DSA:3.20.20.140 3 280 1.3E-27 T 30-10-2018 CL1_0589 9e6b4489dbc9252c7bea0d1f440884b0 65 SUPERFAMILY SSF46924 2 63 3.53E-27 T 30-10-2018 IPR023580 RNA polymerase subunit RPB10 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 CL1_0589 9e6b4489dbc9252c7bea0d1f440884b0 65 Pfam PF01194 RNA polymerases N / 8 kDa subunit 2 58 5.6E-30 T 30-10-2018 IPR000268 DNA-directed RNA polymerase, subunit N/Rpb10 GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 CL1_0589 9e6b4489dbc9252c7bea0d1f440884b0 65 ProDom PD006539 RNA POLYMERASE DNA-DIRECTED SUBUNIT TRANSFERASE NUCLEOTIDYLTRANSFERASE METAL-BINDING ZINC TRANSCRIPTION N 10 49 3.0E-14 T 30-10-2018 IPR000268 DNA-directed RNA polymerase, subunit N/Rpb10 GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 CL1_0589 9e6b4489dbc9252c7bea0d1f440884b0 65 ProSitePatterns PS01112 RNA polymerases N / 8 Kd subunits signature. 2 11 - T 30-10-2018 IPR020789 RNA polymerases, subunit N, zinc binding site GO:0003677|GO:0003899|GO:0006351|GO:0008270 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 CL1_0589 9e6b4489dbc9252c7bea0d1f440884b0 65 Hamap MF_00250 DNA-directed RNA polymerase subunit N [rpoN]. 1 63 23.533 T 30-10-2018 IPR000268 DNA-directed RNA polymerase, subunit N/Rpb10 GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 CL1_0589 9e6b4489dbc9252c7bea0d1f440884b0 65 PIRSF PIRSF005653 1 65 8.3E-32 T 30-10-2018 IPR000268 DNA-directed RNA polymerase, subunit N/Rpb10 GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 CL1_0589 9e6b4489dbc9252c7bea0d1f440884b0 65 Gene3D G3DSA:1.10.10.60 1 65 2.3E-32 T 30-10-2018 CL1_0920 d5da5abf1a7f41d1ccf753d68ef61f51 300 SMART SM00729 56 253 1.9E-5 T 30-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 CL1_0920 d5da5abf1a7f41d1ccf753d68ef61f51 300 Pfam PF04055 Radical SAM superfamily 61 210 1.2E-12 T 30-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CL1_0920 d5da5abf1a7f41d1ccf753d68ef61f51 300 SUPERFAMILY SSF102114 60 261 4.84E-30 T 30-10-2018 CL1_0920 d5da5abf1a7f41d1ccf753d68ef61f51 300 Gene3D G3DSA:3.20.20.70 51 282 3.9E-29 T 30-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CL1_1162 153bbf19f300e4203b0b46b457f06be2 486 Pfam PF13186 Iron-sulfur cluster-binding domain 344 404 1.5E-4 T 30-10-2018 IPR023885 4Fe4S-binding SPASM domain CL1_1162 153bbf19f300e4203b0b46b457f06be2 486 SMART SM00729 102 313 1.1E-4 T 30-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 CL1_1162 153bbf19f300e4203b0b46b457f06be2 486 Gene3D G3DSA:3.20.20.70 99 446 3.5E-80 T 30-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CL1_1162 153bbf19f300e4203b0b46b457f06be2 486 Pfam PF13353 4Fe-4S single cluster domain 109 218 5.7E-11 T 30-10-2018 CL1_1162 153bbf19f300e4203b0b46b457f06be2 486 SUPERFAMILY SSF102114 94 413 8.11E-60 T 30-10-2018 CL1_1162 153bbf19f300e4203b0b46b457f06be2 486 Pfam PF04055 Radical SAM superfamily 107 274 2.3E-19 T 30-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CL1_1162 153bbf19f300e4203b0b46b457f06be2 486 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 344 432 2.5E-17 T 30-10-2018 IPR023885 4Fe4S-binding SPASM domain CL1_0141 752b2ffa0acc4a28fbe11d150efc85b4 367 Pfam PF17179 4Fe-4S dicluster domain 233 326 8.0E-27 T 30-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CL1_0141 752b2ffa0acc4a28fbe11d150efc85b4 367 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 312 323 - T 30-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CL1_0141 752b2ffa0acc4a28fbe11d150efc85b4 367 SUPERFAMILY SSF46548 218 333 4.34E-12 T 30-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 CL1_0141 752b2ffa0acc4a28fbe11d150efc85b4 367 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 233 244 - T 30-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CL1_0915 d6ecc78ceb6c798ff0de9ef70cc966e6 489 SUPERFAMILY SSF161098 277 470 7.46E-24 T 30-10-2018 IPR035906 MetI-like superfamily CL1_0915 d6ecc78ceb6c798ff0de9ef70cc966e6 489 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 301 488 1.8E-29 T 30-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 CL1_0915 d6ecc78ceb6c798ff0de9ef70cc966e6 489 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 11 55 3.3E-5 T 30-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain CL1_0915 d6ecc78ceb6c798ff0de9ef70cc966e6 489 Gene3D G3DSA:1.10.3720.10 273 488 5.7E-23 T 30-10-2018 IPR035906 MetI-like superfamily CL1_0876 b5f06a52448a01899fb95c008d1377ba 313 TIGRFAM TIGR04449 halocin_C8_dom: halocin C8-like bacteriocin domain 240 313 5.6E-11 T 30-10-2018 IPR031033 Halocin C8-like bacteriocin domain CL1_1501 fffbb4f9803d2d5c48365dd9f9af5f2b 141 Pfam PF13380 CoA binding domain 23 137 8.0E-40 T 30-10-2018 IPR003781 CoA-binding GO:0048037 CL1_1501 fffbb4f9803d2d5c48365dd9f9af5f2b 141 Gene3D G3DSA:3.40.50.720 4 141 1.4E-50 T 30-10-2018 CL1_1501 fffbb4f9803d2d5c48365dd9f9af5f2b 141 SUPERFAMILY SSF51735 7 140 9.39E-46 T 30-10-2018 IPR036291 NAD(P)-binding domain superfamily CL1_1501 fffbb4f9803d2d5c48365dd9f9af5f2b 141 SMART SM00881 18 111 2.8E-30 T 30-10-2018 IPR003781 CoA-binding GO:0048037 CL1_1213 5afe66060754c44e7049c6a41ea2d547 98 Pfam PF09876 Predicted metal-binding protein (DUF2103) 5 93 2.0E-21 T 30-10-2018 IPR018664 Protein of unknown function DUF2103, metal-binding CL1_1987 66027b167beedcfeb0e03e4382f572dc 222 TIGRFAM TIGR03724 arch_bud32: Kae1-associated kinase Bud32 4 215 1.8E-72 T 30-10-2018 IPR022495 Serine/threonine-protein kinase Bud32 GO:0004674 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6782315|Reactome: R-HSA-6804756 CL1_1987 66027b167beedcfeb0e03e4382f572dc 222 ProSitePatterns PS00109 Tyrosine protein kinases specific active-site signature. 126 138 - T 30-10-2018 IPR008266 Tyrosine-protein kinase, active site GO:0004672|GO:0006468 CL1_1987 66027b167beedcfeb0e03e4382f572dc 222 SUPERFAMILY SSF56112 12 159 3.91E-29 T 30-10-2018 IPR011009 Protein kinase-like domain superfamily CL1_1987 66027b167beedcfeb0e03e4382f572dc 222 SMART SM00220 1 221 9.1E-4 T 30-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CL1_1987 66027b167beedcfeb0e03e4382f572dc 222 Pfam PF01163 RIO1 family 48 149 1.2E-14 T 30-10-2018 CL1_1987 66027b167beedcfeb0e03e4382f572dc 222 Gene3D G3DSA:3.30.200.20 21 90 1.3E-24 T 30-10-2018 CL1_1987 66027b167beedcfeb0e03e4382f572dc 222 Gene3D G3DSA:1.10.510.10 97 217 5.8E-33 T 30-10-2018 CL1_0192 27b4c80609125c52b7e1d481efda0e23 135 TIGRFAM TIGR01300 CPA3_mnhG_phaG: monovalent cation/proton antiporter, MnhG/PhaG subunit 11 110 4.6E-28 T 30-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 CL1_0192 27b4c80609125c52b7e1d481efda0e23 135 Pfam PF03334 Na+/H+ antiporter subunit 11 95 3.7E-24 T 30-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 CL1_0347 75b27b2ec56ccd0fdbcb0177be40725e 130 TIGRFAM TIGR00307 eS8: ribosomal protein eS8 1 127 5.7E-48 T 30-10-2018 IPR001047 Ribosomal protein S8e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0347 75b27b2ec56ccd0fdbcb0177be40725e 130 Gene3D G3DSA:2.40.10.310 61 130 6.6E-33 T 30-10-2018 CL1_0347 75b27b2ec56ccd0fdbcb0177be40725e 130 ProSitePatterns PS01193 Ribosomal protein S8e signature. 10 29 - T 30-10-2018 IPR018283 Ribosomal protein S8e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0347 75b27b2ec56ccd0fdbcb0177be40725e 130 Pfam PF01201 Ribosomal protein S8e 2 125 1.8E-33 T 30-10-2018 IPR022309 Ribosomal protein S8e/ribosomal biogenesis NSA2 CL1_0347 75b27b2ec56ccd0fdbcb0177be40725e 130 Hamap MF_00029 30S ribosomal protein S8e [rps8e]. 2 126 32.294 T 30-10-2018 IPR020919 Ribosomal protein S8e, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 CL1_1604 d2f35420fe4381c82c2add558bf2db2a 602 SUPERFAMILY SSF52540 134 439 3.33E-29 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_1604 d2f35420fe4381c82c2add558bf2db2a 602 SUPERFAMILY SSF54814 465 520 2.94E-6 T 30-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 CL1_1604 d2f35420fe4381c82c2add558bf2db2a 602 Pfam PF00437 Type II/IV secretion system protein 213 370 2.3E-8 T 30-10-2018 IPR001482 Type II/IV secretion system protein CL1_1604 d2f35420fe4381c82c2add558bf2db2a 602 SMART SM00670 2 115 1.9E-21 T 30-10-2018 IPR002716 PIN domain CL1_1604 d2f35420fe4381c82c2add558bf2db2a 602 Gene3D G3DSA:3.40.50.300 232 391 5.1E-16 T 30-10-2018 CL1_1604 d2f35420fe4381c82c2add558bf2db2a 602 Pfam PF01850 PIN domain 6 117 1.1E-6 T 30-10-2018 IPR002716 PIN domain CL1_1604 d2f35420fe4381c82c2add558bf2db2a 602 SUPERFAMILY SSF88723 1 132 8.13E-16 T 30-10-2018 IPR029060 PIN-like domain superfamily CL1_1604 d2f35420fe4381c82c2add558bf2db2a 602 Gene3D G3DSA:3.40.50.1010 1 127 2.7E-31 T 30-10-2018 CL1_1715 6567a2d7ddbc13339577b9c9b306b072 312 PRINTS PR00721 Stomatin signature 154 172 5.0E-34 T 30-10-2018 IPR001972 Stomatin family GO:0016020 CL1_1715 6567a2d7ddbc13339577b9c9b306b072 312 PRINTS PR00721 Stomatin signature 130 153 5.0E-34 T 30-10-2018 IPR001972 Stomatin family GO:0016020 CL1_1715 6567a2d7ddbc13339577b9c9b306b072 312 PRINTS PR00721 Stomatin signature 75 96 5.0E-34 T 30-10-2018 IPR001972 Stomatin family GO:0016020 CL1_1715 6567a2d7ddbc13339577b9c9b306b072 312 PRINTS PR00721 Stomatin signature 110 127 5.0E-34 T 30-10-2018 IPR001972 Stomatin family GO:0016020 CL1_1715 6567a2d7ddbc13339577b9c9b306b072 312 PRINTS PR00721 Stomatin signature 28 50 5.0E-34 T 30-10-2018 IPR001972 Stomatin family GO:0016020 CL1_1715 6567a2d7ddbc13339577b9c9b306b072 312 PRINTS PR00721 Stomatin signature 173 194 5.0E-34 T 30-10-2018 IPR001972 Stomatin family GO:0016020 CL1_1715 6567a2d7ddbc13339577b9c9b306b072 312 ProSitePatterns PS01270 Band 7 protein family signature. 134 162 - T 30-10-2018 IPR018080 Band 7/stomatin-like, conserved site CL1_1715 6567a2d7ddbc13339577b9c9b306b072 312 SUPERFAMILY SSF117892 52 185 4.84E-46 T 30-10-2018 IPR036013 Band 7/SPFH domain superfamily CL1_1715 6567a2d7ddbc13339577b9c9b306b072 312 Pfam PF01145 SPFH domain / Band 7 family 25 205 6.4E-42 T 30-10-2018 IPR001107 Band 7 domain CL1_1715 6567a2d7ddbc13339577b9c9b306b072 312 Gene3D G3DSA:3.30.479.30 49 180 1.9E-50 T 30-10-2018 CL1_1715 6567a2d7ddbc13339577b9c9b306b072 312 SMART SM00244 21 178 8.4E-73 T 30-10-2018 IPR001107 Band 7 domain CL1_0650 ce6020dd5cf915be6608f902e94eacaa 170 TIGRFAM TIGR00040 yfcE: phosphodiesterase, MJ0936 family 1 155 2.6E-37 T 30-10-2018 IPR000979 Phosphodiesterase MJ0936/Vps29 Reactome: R-HSA-3238698 CL1_0650 ce6020dd5cf915be6608f902e94eacaa 170 ProSitePatterns PS01269 Uncharacterized protein family UPF0025 signature. 108 132 - T 30-10-2018 IPR020935 Phosphodiesterase YfcE, conserved site CL1_0650 ce6020dd5cf915be6608f902e94eacaa 170 Gene3D G3DSA:3.60.21.10 1 159 6.9E-51 T 30-10-2018 IPR029052 Metallo-dependent phosphatase-like CL1_0650 ce6020dd5cf915be6608f902e94eacaa 170 SUPERFAMILY SSF56300 1 157 2.48E-38 T 30-10-2018 CL1_0650 ce6020dd5cf915be6608f902e94eacaa 170 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 1 151 3.1E-33 T 30-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 CL1_1878 6d2f63627b2b0df6025bc4ace831d59c 396 Pfam PF07690 Major Facilitator Superfamily 11 347 3.8E-12 T 30-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CL1_1878 6d2f63627b2b0df6025bc4ace831d59c 396 Gene3D G3DSA:1.20.1250.20 6 381 2.9E-22 T 30-10-2018 CL1_1878 6d2f63627b2b0df6025bc4ace831d59c 396 SUPERFAMILY SSF103473 14 383 2.49E-23 T 30-10-2018 IPR036259 MFS transporter superfamily CL1_0297 7d7d1977066eb2028cbd0435b678f684 275 Gene3D G3DSA:1.25.40.10 63 217 1.4E-7 T 30-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 CL1_1471 73085701161bd7a4dcf3330540d80e55 172 PIRSF PIRSF005067 1 172 1.4E-42 T 30-10-2018 IPR016437 MCT-1/Tma20 CL1_1471 73085701161bd7a4dcf3330540d80e55 172 Gene3D G3DSA:2.30.130.10 79 171 1.0E-34 T 30-10-2018 IPR036974 PUA domain superfamily GO:0003723 CL1_1471 73085701161bd7a4dcf3330540d80e55 172 TIGRFAM TIGR00451 unchar_dom_2: uncharacterized domain 2 53 164 2.6E-28 T 30-10-2018 IPR004521 Uncharacterised domain CHP00451 GO:0003723 CL1_1471 73085701161bd7a4dcf3330540d80e55 172 SUPERFAMILY SSF88697 88 169 3.98E-23 T 30-10-2018 IPR015947 PUA-like superfamily CL1_1471 73085701161bd7a4dcf3330540d80e55 172 Pfam PF01472 PUA domain 89 161 1.8E-23 T 30-10-2018 IPR002478 PUA domain GO:0003723 CL1_1471 73085701161bd7a4dcf3330540d80e55 172 TIGRFAM TIGR03684 arCOG00985: arCOG04150 universal archaeal PUA-domain protein 6 169 1.2E-56 T 30-10-2018 IPR022430 Conserved hypothetical protein CHP03684 CL1_1471 73085701161bd7a4dcf3330540d80e55 172 Gene3D G3DSA:3.10.450.120 1 78 1.5E-35 T 30-10-2018 CL1_1471 73085701161bd7a4dcf3330540d80e55 172 Pfam PF09183 Domain of unknown function (DUF1947) 6 75 3.5E-7 T 30-10-2018 IPR015266 Domain of unknown function DUF1947 CL1_1471 73085701161bd7a4dcf3330540d80e55 172 SMART SM00359 88 163 6.4E-23 T 30-10-2018 IPR002478 PUA domain GO:0003723 CL1_1037 f6058696012d750568ba151de9fe1c44 191 Gene3D G3DSA:1.10.10.10 1 89 1.8E-31 T 30-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CL1_1037 f6058696012d750568ba151de9fe1c44 191 SMART SM00418 11 105 7.8E-11 T 30-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CL1_1037 f6058696012d750568ba151de9fe1c44 191 Pfam PF01022 Bacterial regulatory protein, arsR family 19 63 6.6E-16 T 30-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CL1_1037 f6058696012d750568ba151de9fe1c44 191 Gene3D G3DSA:1.10.20.10 90 191 1.1E-50 T 30-10-2018 IPR009072 Histone-fold GO:0046982 CL1_1037 f6058696012d750568ba151de9fe1c44 191 SUPERFAMILY SSF46785 1 165 2.12E-35 T 30-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CL1_0549 e122d35708352784564d0c1638abacce 138 Gene3D G3DSA:3.30.70.1150 51 138 7.9E-37 T 30-10-2018 IPR027271 Acetolactate synthase/Transcription factor NikR, C-terminal CL1_0549 e122d35708352784564d0c1638abacce 138 SUPERFAMILY SSF55021 53 133 1.88E-28 T 30-10-2018 CL1_0549 e122d35708352784564d0c1638abacce 138 Hamap MF_00476 Nickel-responsive regulator [nikR]. 3 133 30.129 T 30-10-2018 IPR022988 Nickel-responsive transcriptional regulator NikR GO:0003677|GO:0006355|GO:0010045|GO:0016151 CL1_0549 e122d35708352784564d0c1638abacce 138 SUPERFAMILY SSF47598 2 48 3.48E-13 T 30-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 CL1_0549 e122d35708352784564d0c1638abacce 138 Gene3D G3DSA:1.10.1220.10 10 50 4.6E-21 T 30-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CL1_0549 e122d35708352784564d0c1638abacce 138 Pfam PF08753 NikR C terminal nickel binding domain 55 131 2.8E-33 T 30-10-2018 IPR014864 Transcription factor, NikR, nickel binding C-terminal CL1_0549 e122d35708352784564d0c1638abacce 138 Pfam PF01402 Ribbon-helix-helix protein, copG family 5 43 8.5E-8 T 30-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 CL1_1331 3d98ef455fc29e155c14809076919b53 388 Gene3D G3DSA:1.20.1250.20 11 199 2.8E-16 T 30-10-2018 CL1_1331 3d98ef455fc29e155c14809076919b53 388 Gene3D G3DSA:1.20.1250.20 209 388 2.2E-15 T 30-10-2018 CL1_1331 3d98ef455fc29e155c14809076919b53 388 Pfam PF07690 Major Facilitator Superfamily 23 345 6.0E-19 T 30-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CL1_1331 3d98ef455fc29e155c14809076919b53 388 SUPERFAMILY SSF103473 11 386 3.01E-42 T 30-10-2018 IPR036259 MFS transporter superfamily CL1_0976 846058f561b579aa44b74b9f6fb3a9b3 82 Pfam PF01998 Protein of unknown function DUF131 32 74 6.7E-18 T 30-10-2018 IPR002849 Protein of unknown function DUF131 CL1_1182 efcc10dbeaf06106ce937b89a910d542 212 Pfam PF02676 Methyltransferase TYW3 3 184 2.5E-39 T 30-10-2018 IPR003827 tRNA wybutosine-synthesizing protein MetaCyc: PWY-7286|Reactome: R-HSA-6782861 CL1_1182 efcc10dbeaf06106ce937b89a910d542 212 SUPERFAMILY SSF111278 2 182 1.57E-49 T 30-10-2018 IPR036602 tRNA wybutosine-synthesizing-like superfamily MetaCyc: PWY-7286|Reactome: R-HSA-6782861 CL1_1182 efcc10dbeaf06106ce937b89a910d542 212 Hamap MF_00266 tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase [taw3]. 1 186 26.887 T 30-10-2018 IPR022908 tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase GO:0008175|GO:0030488|GO:0031591 MetaCyc: PWY-7286 CL1_1182 efcc10dbeaf06106ce937b89a910d542 212 Gene3D G3DSA:3.30.1960.10 1 183 2.5E-49 T 30-10-2018 IPR036602 tRNA wybutosine-synthesizing-like superfamily MetaCyc: PWY-7286|Reactome: R-HSA-6782861 CL1_0134 50f68f3a20f5f5137abe21e14f1da0b9 289 SUPERFAMILY SSF103481 50 143 1.12E-11 T 30-10-2018 CL1_0134 50f68f3a20f5f5137abe21e14f1da0b9 289 SUPERFAMILY SSF103481 188 288 4.32E-12 T 30-10-2018 CL1_0134 50f68f3a20f5f5137abe21e14f1da0b9 289 Pfam PF00892 EamA-like transporter family 6 141 1.7E-21 T 30-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CL1_0134 50f68f3a20f5f5137abe21e14f1da0b9 289 Pfam PF00892 EamA-like transporter family 153 288 1.5E-23 T 30-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CL1_0367 c3fbfac66ac596805f5ec5cf910b3f97 108 Pfam PF06677 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) 17 49 5.3E-14 T 30-10-2018 IPR009563 Sjoegren syndrome/scleroderma autoantigen 1 CL1_2022 c40beedb714d5a837e74bed02bda535f 248 SMART SM00987 104 240 5.6E-11 T 30-10-2018 CL1_2022 c40beedb714d5a837e74bed02bda535f 248 SUPERFAMILY SSF52141 100 241 4.91E-24 T 30-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CL1_2022 c40beedb714d5a837e74bed02bda535f 248 Gene3D G3DSA:3.40.470.10 59 244 7.8E-25 T 30-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CL1_2022 c40beedb714d5a837e74bed02bda535f 248 Pfam PF03167 Uracil DNA glycosylase superfamily 107 223 1.4E-19 T 30-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CL1_2022 c40beedb714d5a837e74bed02bda535f 248 SMART SM00986 104 240 5.6E-11 T 30-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CL1_1914 1c301d75be1dd7341af84a04aac9e636 257 Pfam PF01163 RIO1 family 65 246 2.7E-53 T 30-10-2018 CL1_1914 1c301d75be1dd7341af84a04aac9e636 257 SMART SM00090 23 257 7.5E-113 T 30-10-2018 IPR000687 RIO kinase GO:0004674|GO:0005524 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6791226 CL1_1914 1c301d75be1dd7341af84a04aac9e636 257 ProSitePatterns PS01245 RIO1/ZK632.3/MJ0444 family signature. 191 202 - T 30-10-2018 IPR018935 RIO kinase, conserved site GO:0004674|GO:0005524 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6791226 CL1_1914 1c301d75be1dd7341af84a04aac9e636 257 Gene3D G3DSA:1.10.510.10 156 256 1.0E-24 T 30-10-2018 CL1_1914 1c301d75be1dd7341af84a04aac9e636 257 Gene3D G3DSA:3.30.200.20 51 152 1.6E-12 T 30-10-2018 CL1_1914 1c301d75be1dd7341af84a04aac9e636 257 SUPERFAMILY SSF56112 45 229 9.64E-23 T 30-10-2018 IPR011009 Protein kinase-like domain superfamily CL1_1347 00be1f8c771f962e08b480ee5558bbb5 374 Pfam PF13353 4Fe-4S single cluster domain 30 116 6.9E-6 T 30-10-2018 CL1_1347 00be1f8c771f962e08b480ee5558bbb5 374 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 29 40 - T 30-10-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CL1_1347 00be1f8c771f962e08b480ee5558bbb5 374 Pfam PF04055 Radical SAM superfamily 27 188 6.4E-17 T 30-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CL1_1347 00be1f8c771f962e08b480ee5558bbb5 374 Pfam PF13186 Iron-sulfur cluster-binding domain 251 329 7.1E-16 T 30-10-2018 IPR023885 4Fe4S-binding SPASM domain CL1_1347 00be1f8c771f962e08b480ee5558bbb5 374 TIGRFAM TIGR04317 W_rSAM_matur: tungsten cofactor oxidoreducase radical SAM maturase 21 364 1.0E-151 T 30-10-2018 IPR027604 Tungsten cofactor oxidoreducase radical SAM maturase CL1_1347 00be1f8c771f962e08b480ee5558bbb5 374 SUPERFAMILY SSF102114 23 334 1.57E-52 T 30-10-2018 CL1_1347 00be1f8c771f962e08b480ee5558bbb5 374 SMART SM00729 23 234 6.8E-4 T 30-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 CL1_0124 243ea1894b7021cd88183f64d4eb5ba1 218 Gene3D G3DSA:3.60.21.10 1 214 1.6E-38 T 30-10-2018 IPR029052 Metallo-dependent phosphatase-like CL1_0124 243ea1894b7021cd88183f64d4eb5ba1 218 SUPERFAMILY SSF56300 1 211 1.82E-65 T 30-10-2018 CL1_0124 243ea1894b7021cd88183f64d4eb5ba1 218 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 1 205 5.2E-18 T 30-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 CL1_0620 2a4b64e8e646d39d56c257d66947ac46 88 TIGRFAM TIGR01158 SUI1_rel: putative translation initiation factor SUI1 4 86 2.1E-34 T 30-10-2018 IPR005872 Archaeal/bacterial translation initiation factor SUI1 GO:0003743 CL1_0620 2a4b64e8e646d39d56c257d66947ac46 88 Hamap MF_00604 Protein translation factor SUI1 homolog. 1 83 23.7 T 30-10-2018 IPR022851 Translation factor SUI1 homolog, archaea CL1_0620 2a4b64e8e646d39d56c257d66947ac46 88 Pfam PF01253 Translation initiation factor SUI1 10 80 8.1E-21 T 30-10-2018 IPR001950 SUI1 domain GO:0003743|GO:0006413 CL1_0620 2a4b64e8e646d39d56c257d66947ac46 88 PIRSF PIRSF037511 2 87 2.5E-25 T 30-10-2018 IPR005872 Archaeal/bacterial translation initiation factor SUI1 GO:0003743 CL1_0620 2a4b64e8e646d39d56c257d66947ac46 88 Gene3D G3DSA:3.30.780.10 10 88 4.1E-29 T 30-10-2018 CL1_0620 2a4b64e8e646d39d56c257d66947ac46 88 SUPERFAMILY SSF55159 8 81 9.42E-24 T 30-10-2018 IPR036877 SUI1 domain superfamily GO:0003743|GO:0006413 CL1_0882 77fe936ebc6e0135b796872c7d0246ba 448 Gene3D G3DSA:3.40.50.2000 2 436 1.4E-109 T 30-10-2018 CL1_0882 77fe936ebc6e0135b796872c7d0246ba 448 Pfam PF00534 Glycosyl transferases group 1 251 418 8.9E-25 T 30-10-2018 IPR001296 Glycosyl transferase, family 1 CL1_0882 77fe936ebc6e0135b796872c7d0246ba 448 Pfam PF08323 Starch synthase catalytic domain 2 201 2.0E-36 T 30-10-2018 IPR013534 Starch synthase, catalytic domain KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 CL1_0882 77fe936ebc6e0135b796872c7d0246ba 448 SUPERFAMILY SSF53756 1 440 3.49E-89 T 30-10-2018 CL1_0882 77fe936ebc6e0135b796872c7d0246ba 448 Gene3D G3DSA:3.40.50.2000 218 426 1.4E-109 T 30-10-2018 CL1_1810 b579f17ca81c2c5592f8a9e8b44c8e77 213 SUPERFAMILY SSF55186 85 210 5.62E-32 T 30-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 CL1_1810 b579f17ca81c2c5592f8a9e8b44c8e77 213 SMART SM00863 165 208 3.8E-7 T 30-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 CL1_1810 b579f17ca81c2c5592f8a9e8b44c8e77 213 SUPERFAMILY SSF50447 1 84 9.89E-21 T 30-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily CL1_1810 b579f17ca81c2c5592f8a9e8b44c8e77 213 Gene3D G3DSA:3.30.980.10 85 212 1.5E-40 T 30-10-2018 CL1_1810 b579f17ca81c2c5592f8a9e8b44c8e77 213 Gene3D G3DSA:2.40.30.130 13 84 1.3E-30 T 30-10-2018 CL1_1810 b579f17ca81c2c5592f8a9e8b44c8e77 213 Pfam PF01411 tRNA synthetases class II (A) 14 87 8.9E-11 T 30-10-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 CL1_1810 b579f17ca81c2c5592f8a9e8b44c8e77 213 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 170 208 7.3E-8 T 30-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 CL1_1073 115a663157d912fac1186a76a2afb205 143 SUPERFAMILY SSF88697 1 142 1.33E-44 T 30-10-2018 IPR015947 PUA-like superfamily CL1_1073 115a663157d912fac1186a76a2afb205 143 Hamap MF_00771 UPF0310 protein . 1 143 27.934 T 30-10-2018 IPR022996 Uncharacterised protein family UPF0310 CL1_1073 115a663157d912fac1186a76a2afb205 143 Pfam PF01878 EVE domain 2 141 6.1E-27 T 30-10-2018 IPR002740 EVE domain CL1_1073 115a663157d912fac1186a76a2afb205 143 Gene3D G3DSA:3.10.590.10 1 143 7.5E-63 T 30-10-2018 CL1_1793 2c3216755c7c72ca9f69d006ea19941a 146 Pfam PF02996 Prefoldin subunit 17 136 8.2E-27 T 30-10-2018 IPR004127 Prefoldin alpha-like CL1_1793 2c3216755c7c72ca9f69d006ea19941a 146 SUPERFAMILY SSF46579 7 138 4.45E-30 T 30-10-2018 CL1_1793 2c3216755c7c72ca9f69d006ea19941a 146 Hamap MF_00308 Prefoldin subunit alpha [pfdA]. 1 137 16.068 T 30-10-2018 IPR011599 Prefoldin alpha subunit, archaea-type GO:0006457|GO:0016272|GO:0051082 Reactome: R-HSA-389957 CL1_1793 2c3216755c7c72ca9f69d006ea19941a 146 TIGRFAM TIGR00293 TIGR00293: prefoldin, alpha subunit 8 137 8.9E-37 T 30-10-2018 IPR011599 Prefoldin alpha subunit, archaea-type GO:0006457|GO:0016272|GO:0051082 Reactome: R-HSA-389957 CL1_1793 2c3216755c7c72ca9f69d006ea19941a 146 Gene3D G3DSA:1.10.287.370 1 146 3.1E-45 T 30-10-2018 IPR009053 Prefoldin CL1_0775 32ccf5b80cde7b1d1f958d473ce5aa34 247 Pfam PF09874 Predicted membrane protein (DUF2101) 22 228 1.1E-79 T 30-10-2018 IPR018663 Protein of unknown function DUF2101, membrane CL1_0035 b5deb0a400e90b4fb30804896af4a9ef 431 Pfam PF08543 Phosphomethylpyrimidine kinase 10 238 1.2E-70 T 30-10-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 CL1_0035 b5deb0a400e90b4fb30804896af4a9ef 431 Pfam PF10120 Thiamine-phosphate synthase 258 423 1.1E-53 T 30-10-2018 IPR019293 Thiamine-phosphate synthase ThiN GO:0004789 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CL1_0035 b5deb0a400e90b4fb30804896af4a9ef 431 SUPERFAMILY SSF53639 251 425 7.85E-56 T 30-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily CL1_0035 b5deb0a400e90b4fb30804896af4a9ef 431 Gene3D G3DSA:3.40.225.10 248 428 6.7E-64 T 30-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily CL1_0035 b5deb0a400e90b4fb30804896af4a9ef 431 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 3 233 1.5E-64 T 30-10-2018 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CL1_0035 b5deb0a400e90b4fb30804896af4a9ef 431 Gene3D G3DSA:3.40.1190.20 1 247 2.9E-69 T 30-10-2018 IPR029056 Ribokinase-like CL1_0035 b5deb0a400e90b4fb30804896af4a9ef 431 SUPERFAMILY SSF53613 3 243 7.17E-58 T 30-10-2018 IPR029056 Ribokinase-like CL1_1226 95be309f0050d9d63dedb465425ac5fd 358 Gene3D G3DSA:1.10.10.10 284 356 2.4E-24 T 30-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CL1_1226 95be309f0050d9d63dedb465425ac5fd 358 SUPERFAMILY SSF52540 1 280 2.84E-41 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_1226 95be309f0050d9d63dedb465425ac5fd 358 Pfam PF01637 ATPase domain predominantly from Archaea 14 247 2.3E-19 T 30-10-2018 IPR011579 ATPase domain GO:0005524 CL1_1226 95be309f0050d9d63dedb465425ac5fd 358 Gene3D G3DSA:3.40.50.300 1 205 1.1E-41 T 30-10-2018 CL1_1226 95be309f0050d9d63dedb465425ac5fd 358 SUPERFAMILY SSF46785 282 354 6.81E-15 T 30-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CL1_1226 95be309f0050d9d63dedb465425ac5fd 358 Gene3D G3DSA:1.10.8.60 206 283 3.5E-23 T 30-10-2018 CL1_1262 c46e2802933d03c497916459cfa8ee59 283 TIGRFAM TIGR00722 ttdA_fumA_fumB: hydrolyase, tartrate alpha subunit/fumarate domain protein, Fe-S type 4 272 3.9E-120 T 30-10-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 CL1_1262 c46e2802933d03c497916459cfa8ee59 283 Pfam PF05681 Fumarate hydratase (Fumerase) 6 269 1.5E-96 T 30-10-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 CL1_0022 d5a8c41667f09e6566437e0b6796a430 512 Pfam PF00005 ABC transporter 23 173 1.8E-26 T 30-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CL1_0022 d5a8c41667f09e6566437e0b6796a430 512 SMART SM00382 32 221 3.4E-17 T 30-10-2018 IPR003593 AAA+ ATPase domain CL1_0022 d5a8c41667f09e6566437e0b6796a430 512 SUPERFAMILY SSF52540 5 231 7.07E-60 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_0022 d5a8c41667f09e6566437e0b6796a430 512 Gene3D G3DSA:3.40.50.300 257 502 2.5E-42 T 30-10-2018 CL1_0022 d5a8c41667f09e6566437e0b6796a430 512 SUPERFAMILY SSF52540 258 495 6.16E-45 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_0022 d5a8c41667f09e6566437e0b6796a430 512 Gene3D G3DSA:3.40.50.300 1 242 4.9E-58 T 30-10-2018 CL1_0022 d5a8c41667f09e6566437e0b6796a430 512 ProSitePatterns PS00211 ABC transporters family signature. 407 421 - T 30-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CL1_0022 d5a8c41667f09e6566437e0b6796a430 512 Pfam PF00005 ABC transporter 278 434 7.8E-15 T 30-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CL1_0916 9e217e0b027378af31eac2b6b4791a8e 351 Gene3D G3DSA:1.10.3720.10 114 341 7.0E-17 T 30-10-2018 IPR035906 MetI-like superfamily CL1_0916 9e217e0b027378af31eac2b6b4791a8e 351 SUPERFAMILY SSF161098 122 327 5.89E-15 T 30-10-2018 IPR035906 MetI-like superfamily CL1_0916 9e217e0b027378af31eac2b6b4791a8e 351 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 141 344 2.8E-35 T 30-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 CL1_1137 11cfb58c1532c2181355b5e6c655bc37 148 Pfam PF04039 Domain related to MnhB subunit of Na+/H+ antiporter 8 134 6.0E-27 T 30-10-2018 IPR007182 Na+/H+ antiporter MnhB subunit-related protein CL1_1798 6ab9174f681992d5e05148957bf8c664 262 PRINTS PR00111 Alpha/beta hydrolase fold signature 83 96 5.3E-6 T 30-10-2018 IPR000073 Alpha/beta hydrolase fold-1 CL1_1798 6ab9174f681992d5e05148957bf8c664 262 PRINTS PR00111 Alpha/beta hydrolase fold signature 97 110 5.3E-6 T 30-10-2018 IPR000073 Alpha/beta hydrolase fold-1 CL1_1798 6ab9174f681992d5e05148957bf8c664 262 PRINTS PR00111 Alpha/beta hydrolase fold signature 40 55 5.3E-6 T 30-10-2018 IPR000073 Alpha/beta hydrolase fold-1 CL1_1798 6ab9174f681992d5e05148957bf8c664 262 PRINTS PR00111 Alpha/beta hydrolase fold signature 195 209 5.3E-6 T 30-10-2018 IPR000073 Alpha/beta hydrolase fold-1 CL1_1798 6ab9174f681992d5e05148957bf8c664 262 Pfam PF12146 Serine aminopeptidase, S33 14 240 1.7E-66 T 30-10-2018 IPR022742 Serine aminopeptidase, S33 CL1_1798 6ab9174f681992d5e05148957bf8c664 262 SUPERFAMILY SSF53474 10 253 1.88E-47 T 30-10-2018 IPR029058 Alpha/Beta hydrolase fold CL1_1798 6ab9174f681992d5e05148957bf8c664 262 Gene3D G3DSA:3.40.50.1820 1 259 1.0E-64 T 30-10-2018 IPR029058 Alpha/Beta hydrolase fold CL1_0980 d3df9f2d63b13a21e5e111f6177c45a5 286 Gene3D G3DSA:3.30.70.1350 207 282 6.6E-21 T 30-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 CL1_0980 d3df9f2d63b13a21e5e111f6177c45a5 286 SUPERFAMILY SSF160240 205 280 7.98E-22 T 30-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 CL1_0980 d3df9f2d63b13a21e5e111f6177c45a5 286 Pfam PF16916 Dimerisation domain of Zinc Transporter 208 280 6.6E-23 T 30-10-2018 IPR027470 Cation efflux protein, cytoplasmic domain CL1_0980 d3df9f2d63b13a21e5e111f6177c45a5 286 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 6 281 8.6E-83 T 30-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CL1_0980 d3df9f2d63b13a21e5e111f6177c45a5 286 SUPERFAMILY SSF161111 5 202 5.89E-58 T 30-10-2018 IPR027469 Cation efflux transmembrane domain superfamily CL1_0980 d3df9f2d63b13a21e5e111f6177c45a5 286 Gene3D G3DSA:1.20.1510.10 4 200 7.3E-64 T 30-10-2018 IPR027469 Cation efflux transmembrane domain superfamily CL1_0980 d3df9f2d63b13a21e5e111f6177c45a5 286 Pfam PF01545 Cation efflux family 8 200 1.3E-47 T 30-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CL1_0146 f2ae6baa026efafc0e6e40dde1ad6876 143 Pfam PF01850 PIN domain 4 130 4.6E-21 T 30-10-2018 IPR002716 PIN domain CL1_0146 f2ae6baa026efafc0e6e40dde1ad6876 143 Gene3D G3DSA:3.40.50.1010 3 140 8.9E-18 T 30-10-2018 CL1_0146 f2ae6baa026efafc0e6e40dde1ad6876 143 SUPERFAMILY SSF88723 1 130 3.64E-20 T 30-10-2018 IPR029060 PIN-like domain superfamily CL1_0146 f2ae6baa026efafc0e6e40dde1ad6876 143 SMART SM00670 2 131 1.2E-12 T 30-10-2018 IPR002716 PIN domain CL1_0146 f2ae6baa026efafc0e6e40dde1ad6876 143 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 4 139 10.979 T 30-10-2018 IPR022907 VapC family GO:0004540 CL1_0738 e8fba79a523808a76b87fe200742eaad 112 SUPERFAMILY SSF117782 4 108 6.67E-36 T 30-10-2018 IPR035439 UPF0145 domain superfamily CL1_0738 e8fba79a523808a76b87fe200742eaad 112 Pfam PF01906 Putative heavy-metal-binding 4 106 1.5E-36 T 30-10-2018 IPR002765 Uncharacterised protein family UPF0145 CL1_0738 e8fba79a523808a76b87fe200742eaad 112 Hamap MF_00338 UPF0145 protein YbjQ [ybjQ]. 4 106 24.817 T 30-10-2018 IPR002765 Uncharacterised protein family UPF0145 CL1_0738 e8fba79a523808a76b87fe200742eaad 112 Gene3D G3DSA:3.30.110.70 4 111 1.3E-32 T 30-10-2018 CL1_0324 81a575bd276d466d811d5fab773c4def 1069 Gene3D G3DSA:2.60.40.10 631 729 9.9E-9 T 30-10-2018 IPR013783 Immunoglobulin-like fold CL1_1281 4c7969704d23a190eb8001bf6cf2a05e 1073 SUPERFAMILY SSF54001 197 325 2.66E-23 T 30-10-2018 IPR038765 Papain-like cysteine peptidase superfamily CL1_1281 4c7969704d23a190eb8001bf6cf2a05e 1073 Gene3D G3DSA:3.10.620.30 186 326 4.4E-18 T 30-10-2018 CL1_1281 4c7969704d23a190eb8001bf6cf2a05e 1073 Pfam PF01841 Transglutaminase-like superfamily 205 317 6.4E-22 T 30-10-2018 IPR002931 Transglutaminase-like CL1_1281 4c7969704d23a190eb8001bf6cf2a05e 1073 SMART SM00460 251 319 2.1E-18 T 30-10-2018 IPR002931 Transglutaminase-like CL1_1296 4a329feb71392a63e3dc35b8aac37b94 137 SUPERFAMILY SSF111038 1 137 1.12E-43 T 30-10-2018 IPR035917 YjbQ-like superfamily CL1_1296 4a329feb71392a63e3dc35b8aac37b94 137 PIRSF PIRSF004681 1 137 1.6E-37 T 30-10-2018 IPR001602 Uncharacterised protein family UPF0047 CL1_1296 4a329feb71392a63e3dc35b8aac37b94 137 TIGRFAM TIGR00149 TIGR00149_YjbQ: secondary thiamine-phosphate synthase enzyme 8 137 2.7E-39 T 30-10-2018 IPR001602 Uncharacterised protein family UPF0047 CL1_1296 4a329feb71392a63e3dc35b8aac37b94 137 Pfam PF01894 Uncharacterised protein family UPF0047 20 134 3.2E-36 T 30-10-2018 IPR001602 Uncharacterised protein family UPF0047 CL1_1296 4a329feb71392a63e3dc35b8aac37b94 137 Gene3D G3DSA:2.60.120.460 1 137 3.3E-49 T 30-10-2018 IPR035917 YjbQ-like superfamily CL1_1814 d3d714eafd095349339d1c59b630dd5d 317 TIGRFAM TIGR00287 cas1: CRISPR-associated endonuclease Cas1 5 311 7.8E-81 T 30-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 CL1_1814 d3d714eafd095349339d1c59b630dd5d 317 Gene3D G3DSA:1.20.120.920 82 315 4.3E-58 T 30-10-2018 CL1_1814 d3d714eafd095349339d1c59b630dd5d 317 TIGRFAM TIGR03641 cas1_HMARI: CRISPR-associated endonuclease Cas1, subtype I-B/HMARI/TNEAP 4 317 3.7E-122 T 30-10-2018 IPR019858 CRISPR-associated protein Cas1, HMARI/TNEAP subtype GO:0004520|GO:0043571|GO:0046872 CL1_1814 d3d714eafd095349339d1c59b630dd5d 317 Pfam PF01867 CRISPR associated protein Cas1 5 271 1.1E-73 T 30-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 CL1_1814 d3d714eafd095349339d1c59b630dd5d 317 Hamap MF_01470 CRISPR-associated endonuclease Cas1 [cas1]. 2 302 24.109 T 30-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 CL1_1814 d3d714eafd095349339d1c59b630dd5d 317 Gene3D G3DSA:3.100.10.20 1 80 7.6E-27 T 30-10-2018 CL1_0618 8cf4fb355a1009d108a565b054195862 111 TIGRFAM TIGR03630 uS17_arch: ribosomal protein uS17 4 104 4.7E-47 T 30-10-2018 IPR028333 Ribosomal protein S17, archaeal/eukaryotic Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0618 8cf4fb355a1009d108a565b054195862 111 PRINTS PR00973 Ribosomal protein S17 family signature 82 92 3.9E-11 T 30-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CL1_0618 8cf4fb355a1009d108a565b054195862 111 PRINTS PR00973 Ribosomal protein S17 family signature 49 72 3.9E-11 T 30-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CL1_0618 8cf4fb355a1009d108a565b054195862 111 PRINTS PR00973 Ribosomal protein S17 family signature 92 99 3.9E-11 T 30-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CL1_0618 8cf4fb355a1009d108a565b054195862 111 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 31 102 5.0E-33 T 30-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CL1_0618 8cf4fb355a1009d108a565b054195862 111 SUPERFAMILY SSF50249 29 109 1.85E-28 T 30-10-2018 IPR012340 Nucleic acid-binding, OB-fold CL1_0618 8cf4fb355a1009d108a565b054195862 111 Gene3D G3DSA:2.40.50.1000 1 111 5.6E-38 T 30-10-2018 CL1_0618 8cf4fb355a1009d108a565b054195862 111 Pfam PF00366 Ribosomal protein S17 35 102 6.6E-27 T 30-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CL1_0618 8cf4fb355a1009d108a565b054195862 111 ProSitePatterns PS00056 Ribosomal protein S17 signature. 82 94 - T 30-10-2018 IPR019979 Ribosomal protein S17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0618 8cf4fb355a1009d108a565b054195862 111 Hamap MF_01345_A 30S ribosomal protein S17 [rpsQ]. 2 106 33.201 T 30-10-2018 IPR019978 Ribosomal protein S17, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 CL1_1658 b05492909a1b4a690ce341ec5c33c85f 237 PIRSF PIRSF015736 1 237 1.9E-89 T 30-10-2018 IPR026286 Maleate isomerase/Arylmalonate decarboxylase CL1_1658 b05492909a1b4a690ce341ec5c33c85f 237 Gene3D G3DSA:3.40.50.12500 6 237 9.8E-89 T 30-10-2018 CL1_1658 b05492909a1b4a690ce341ec5c33c85f 237 Pfam PF01177 Asp/Glu/Hydantoin racemase 9 215 6.3E-14 T 30-10-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CL1_0978 b736966aa9908b50f14e1784900ecd78 384 TIGRFAM TIGR03812 tyr_de_CO2_Arch: tyrosine decarboxylase MnfA 9 379 8.9E-169 T 30-10-2018 IPR020931 Decarboxylase MfnA, archaea GO:0016831 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 CL1_0978 b736966aa9908b50f14e1784900ecd78 384 SUPERFAMILY SSF53383 2 383 7.66E-107 T 30-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase CL1_0978 b736966aa9908b50f14e1784900ecd78 384 Gene3D G3DSA:3.90.1150.10 6 374 1.1E-126 T 30-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 CL1_0978 b736966aa9908b50f14e1784900ecd78 384 ProSitePatterns PS00392 DDC / GAD / HDC / TyrDC pyridoxal-phosphate attachment site. 224 245 - T 30-10-2018 IPR021115 Pyridoxal-phosphate binding site GO:0016831 CL1_0978 b736966aa9908b50f14e1784900ecd78 384 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 74 331 6.5E-34 T 30-10-2018 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 CL1_0978 b736966aa9908b50f14e1784900ecd78 384 Hamap MF_01610 Probable L-tyrosine/L-aspartate decarboxylase [mfnA]. 14 381 51.855 T 30-10-2018 IPR020931 Decarboxylase MfnA, archaea GO:0016831 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 CL1_0978 b736966aa9908b50f14e1784900ecd78 384 Gene3D G3DSA:3.40.640.10 40 290 1.1E-126 T 30-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 CL1_0895 3e6b68f88c3a63428c3030c353396339 120 Pfam PF05402 Coenzyme PQQ synthesis protein D (PqqD) 26 102 2.3E-14 T 30-10-2018 IPR008792 Coenzyme PQQ synthesis D CL1_0895 3e6b68f88c3a63428c3030c353396339 120 Gene3D G3DSA:1.10.10.1150 41 104 1.9E-7 T 30-10-2018 CL1_0651 ef4ce4cc38592e6d1988291966a258be 164 Gene3D G3DSA:1.20.58.2050 1 164 1.7E-85 T 30-10-2018 IPR038437 GINS complex, subunit Psf3 superfamily Reactome: R-HSA-176974 CL1_0651 ef4ce4cc38592e6d1988291966a258be 164 Pfam PF05916 GINS complex protein 28 147 3.4E-9 T 30-10-2018 IPR021151 GINS subunit, domain A Reactome: R-HSA-176974 CL1_0157 569486870db59f490f11b194f71aa8f5 149 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 32 51 4.6E-11 T 30-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 CL1_0157 569486870db59f490f11b194f71aa8f5 149 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 5 21 4.6E-11 T 30-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 CL1_0157 569486870db59f490f11b194f71aa8f5 149 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 21 32 4.6E-11 T 30-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 CL1_0157 569486870db59f490f11b194f71aa8f5 149 Gene3D G3DSA:1.10.10.10 1 56 5.7E-20 T 30-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CL1_0157 569486870db59f490f11b194f71aa8f5 149 Gene3D G3DSA:3.30.70.920 57 149 2.2E-29 T 30-10-2018 CL1_0157 569486870db59f490f11b194f71aa8f5 149 SMART SM00344 5 111 6.7E-21 T 30-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CL1_0157 569486870db59f490f11b194f71aa8f5 149 SUPERFAMILY SSF46785 5 65 1.71E-14 T 30-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CL1_0157 569486870db59f490f11b194f71aa8f5 149 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 20 36 8.7E-5 T 30-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CL1_0157 569486870db59f490f11b194f71aa8f5 149 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 36 51 8.7E-5 T 30-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CL1_0157 569486870db59f490f11b194f71aa8f5 149 Pfam PF13412 Winged helix-turn-helix DNA-binding 6 52 1.1E-15 T 30-10-2018 CL1_0157 569486870db59f490f11b194f71aa8f5 149 SUPERFAMILY SSF54909 66 146 1.79E-6 T 30-10-2018 IPR011008 Dimeric alpha-beta barrel CL1_0454 166cce48b8c3f9ebbf89426abcbd94f2 193 ProDom PD022789 MEMBRANE SURFACE PRECURSOR SIGNAL PROTEIN YBJE TRANSMEMBRANE INNER PREDICTED STY0934 24 193 3.0E-43 T 30-10-2018 IPR005642 Lysine exporter LysO CL1_0454 166cce48b8c3f9ebbf89426abcbd94f2 193 Pfam PF03956 Lysine exporter LysO 9 190 1.5E-58 T 30-10-2018 IPR005642 Lysine exporter LysO CL1_0555 1355ecd242a9d699b2ecb406efeee640 123 Gene3D G3DSA:3.40.50.1010 2 122 1.7E-8 T 30-10-2018 CL1_0555 1355ecd242a9d699b2ecb406efeee640 123 SUPERFAMILY SSF88723 1 116 3.36E-13 T 30-10-2018 IPR029060 PIN-like domain superfamily CL1_0555 1355ecd242a9d699b2ecb406efeee640 123 Pfam PF01850 PIN domain 2 111 2.2E-12 T 30-10-2018 IPR002716 PIN domain CL1_0338 3e226963ded5adc81a819c2877575ed5 267 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 1 227 30.405 T 30-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 CL1_0338 3e226963ded5adc81a819c2877575ed5 267 Gene3D G3DSA:3.30.70.580 1 102 5.0E-23 T 30-10-2018 CL1_0338 3e226963ded5adc81a819c2877575ed5 267 PIRSF PIRSF001430 1 243 3.6E-75 T 30-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 CL1_0338 3e226963ded5adc81a819c2877575ed5 267 Pfam PF01416 tRNA pseudouridine synthase 129 228 4.3E-23 T 30-10-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CL1_0338 3e226963ded5adc81a819c2877575ed5 267 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 2 221 1.9E-51 T 30-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 CL1_0338 3e226963ded5adc81a819c2877575ed5 267 SUPERFAMILY SSF55120 1 232 1.73E-64 T 30-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 CL1_0338 3e226963ded5adc81a819c2877575ed5 267 Gene3D G3DSA:3.30.70.660 103 226 1.9E-26 T 30-10-2018 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0003723|GO:0009982 CL1_0702 16de5895b1f988e766f9064c9ccded66 205 Hamap MF_00645 Protein . 5 188 41.996 T 30-10-2018 IPR023472 Uncharacterised protein family MJ0810 CL1_0702 16de5895b1f988e766f9064c9ccded66 205 TIGRFAM TIGR00296 TIGR00296: uncharacterized protein, PH0010 family 4 197 1.8E-69 T 30-10-2018 IPR023473 AMMECR1 CL1_0702 16de5895b1f988e766f9064c9ccded66 205 TIGRFAM TIGR04335 AmmeMemoSam_A: AmmeMemoRadiSam system protein A 11 190 1.5E-59 T 30-10-2018 IPR027623 AmmeMemoRadiSam system protein A CL1_0702 16de5895b1f988e766f9064c9ccded66 205 Gene3D G3DSA:3.30.700.20 9 192 1.2E-73 T 30-10-2018 IPR027485 AMMECR1, N-terminal CL1_0702 16de5895b1f988e766f9064c9ccded66 205 Gene3D G3DSA:3.30.1490.150 117 190 1.2E-73 T 30-10-2018 CL1_0702 16de5895b1f988e766f9064c9ccded66 205 SUPERFAMILY SSF143447 4 202 1.44E-70 T 30-10-2018 IPR036071 AMMECR1 domain superfamily CL1_0702 16de5895b1f988e766f9064c9ccded66 205 Pfam PF01871 AMMECR1 13 190 5.6E-55 T 30-10-2018 IPR002733 AMMECR1 domain CL1_1774 1f94d8e0639a17d0f54647c63f2a3575 177 Pfam PF00571 CBS domain 72 125 1.1E-10 T 30-10-2018 IPR000644 CBS domain CL1_1774 1f94d8e0639a17d0f54647c63f2a3575 177 Pfam PF00571 CBS domain 7 60 1.6E-11 T 30-10-2018 IPR000644 CBS domain CL1_1774 1f94d8e0639a17d0f54647c63f2a3575 177 SUPERFAMILY SSF54631 5 126 4.8E-31 T 30-10-2018 CL1_1774 1f94d8e0639a17d0f54647c63f2a3575 177 SMART SM00116 14 61 6.5E-9 T 30-10-2018 IPR000644 CBS domain CL1_1774 1f94d8e0639a17d0f54647c63f2a3575 177 SMART SM00116 79 126 9.3E-9 T 30-10-2018 IPR000644 CBS domain CL1_1774 1f94d8e0639a17d0f54647c63f2a3575 177 Gene3D G3DSA:3.10.580.10 3 175 9.7E-42 T 30-10-2018 CL1_1089 f5f6328d71aeb11424f511436829340a 278 Pfam PF01513 ATP-NAD kinase 2 261 1.2E-69 T 30-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 CL1_1089 f5f6328d71aeb11424f511436829340a 278 SUPERFAMILY SSF111331 2 277 1.31E-71 T 30-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily CL1_1089 f5f6328d71aeb11424f511436829340a 278 Hamap MF_00361 NAD kinase [nadK]. 1 276 29.758 T 30-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 CL1_1089 f5f6328d71aeb11424f511436829340a 278 Gene3D G3DSA:3.40.50.10330 20 267 8.8E-70 T 30-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 CL1_1089 f5f6328d71aeb11424f511436829340a 278 Gene3D G3DSA:2.60.200.30 121 254 8.8E-70 T 30-10-2018 IPR017437 ATP-NAD kinase, PpnK-type, C-terminal GO:0003951|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 CL1_0105 a56281286a238ba1975ee30965315996 120 Pfam PF09685 Domain of unknown function (DUF4870) 29 106 3.2E-9 T 30-10-2018 IPR019109 Protein of unknown function DUF4870 CL1_0711 1bc6a370701e8d12bd284d29d1833309 445 PIRSF PIRSF005353 1 442 1.2E-167 T 30-10-2018 IPR026033 Purine permease PbuG-like CL1_0711 1bc6a370701e8d12bd284d29d1833309 445 Pfam PF00860 Permease family 19 401 4.9E-45 T 30-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 CL1_0823 f3ca421232eb408661f1eb481b1ef1a9 371 Gene3D G3DSA:1.10.10.10 300 369 2.0E-6 T 30-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CL1_0823 f3ca421232eb408661f1eb481b1ef1a9 371 SUPERFAMILY SSF52540 7 289 3.79E-41 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_0823 f3ca421232eb408661f1eb481b1ef1a9 371 Gene3D G3DSA:3.40.50.300 7 216 7.9E-40 T 30-10-2018 CL1_0823 f3ca421232eb408661f1eb481b1ef1a9 371 SUPERFAMILY SSF46785 304 367 3.76E-5 T 30-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CL1_0823 f3ca421232eb408661f1eb481b1ef1a9 371 Gene3D G3DSA:1.10.8.60 218 295 3.9E-19 T 30-10-2018 CL1_0823 f3ca421232eb408661f1eb481b1ef1a9 371 Pfam PF01637 ATPase domain predominantly from Archaea 21 259 5.7E-20 T 30-10-2018 IPR011579 ATPase domain GO:0005524 CL1_0909 38601fc5acf36eeee0602b7bc7be318f 440 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 16 438 4.8E-173 T 30-10-2018 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CL1_0909 38601fc5acf36eeee0602b7bc7be318f 440 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 16 90 3.1E-20 T 30-10-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 CL1_0909 38601fc5acf36eeee0602b7bc7be318f 440 SUPERFAMILY SSF55931 98 439 5.79E-122 T 30-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 CL1_0909 38601fc5acf36eeee0602b7bc7be318f 440 ProSitePatterns PS00180 Glutamine synthetase signature 1. 49 67 - T 30-10-2018 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 CL1_0909 38601fc5acf36eeee0602b7bc7be318f 440 Pfam PF00120 Glutamine synthetase, catalytic domain 98 435 3.0E-129 T 30-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CL1_0909 38601fc5acf36eeee0602b7bc7be318f 440 SMART SM01230 97 340 3.0E-132 T 30-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CL1_0909 38601fc5acf36eeee0602b7bc7be318f 440 Gene3D G3DSA:3.10.20.70 12 99 3.8E-22 T 30-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CL1_0909 38601fc5acf36eeee0602b7bc7be318f 440 SUPERFAMILY SSF54368 16 96 3.27E-19 T 30-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CL1_0909 38601fc5acf36eeee0602b7bc7be318f 440 Gene3D G3DSA:3.30.590.10 100 440 9.8E-128 T 30-10-2018 CL1_0909 38601fc5acf36eeee0602b7bc7be318f 440 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 223 238 - T 30-10-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 CL1_1254 55b4251206732dd88bd94dbfef447e47 75 SUPERFAMILY SSF89447 2 51 1.44E-6 T 30-10-2018 IPR037914 SpoVT-AbrB domain superfamily CL1_1254 55b4251206732dd88bd94dbfef447e47 75 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 1 39 1.9E-7 T 30-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 CL1_0982 0ccd8ac6687644c28c08ba5f2bcad590 379 Hamap MF_00066 Sulfate adenylyltransferase [sat]. 26 376 50.26 T 30-10-2018 IPR020792 Sulphate adenylyltransferase, prokaryotic-type GO:0000103|GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 CL1_0982 0ccd8ac6687644c28c08ba5f2bcad590 379 SUPERFAMILY SSF52374 164 372 4.44E-78 T 30-10-2018 CL1_0982 0ccd8ac6687644c28c08ba5f2bcad590 379 Gene3D G3DSA:3.10.400.10 1 159 4.5E-47 T 30-10-2018 CL1_0982 0ccd8ac6687644c28c08ba5f2bcad590 379 Pfam PF14306 PUA-like domain 4 156 2.4E-50 T 30-10-2018 IPR025980 ATP-sulfurylase PUA-like domain KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 CL1_0982 0ccd8ac6687644c28c08ba5f2bcad590 379 Gene3D G3DSA:3.40.50.620 164 373 5.0E-90 T 30-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CL1_0982 0ccd8ac6687644c28c08ba5f2bcad590 379 Pfam PF01747 ATP-sulfurylase 164 372 3.5E-86 T 30-10-2018 IPR024951 Sulphate adenylyltransferase catalytic domain GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 CL1_0982 0ccd8ac6687644c28c08ba5f2bcad590 379 SUPERFAMILY SSF88697 4 161 6.16E-49 T 30-10-2018 IPR015947 PUA-like superfamily CL1_0982 0ccd8ac6687644c28c08ba5f2bcad590 379 TIGRFAM TIGR00339 sopT: sulfate adenylyltransferase 5 371 1.5E-118 T 30-10-2018 IPR002650 Sulphate adenylyltransferase GO:0000103|GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 CL1_0416 0278c98a31736f675b2c00907baf0e26 205 SUPERFAMILY SSF52540 1 201 3.74E-54 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_0416 0278c98a31736f675b2c00907baf0e26 205 Hamap MF_00165 Thymidylate kinase [tmk]. 1 202 28.586 T 30-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 CL1_0416 0278c98a31736f675b2c00907baf0e26 205 Gene3D G3DSA:3.40.50.300 1 202 7.7E-70 T 30-10-2018 CL1_0416 0278c98a31736f675b2c00907baf0e26 205 ProSitePatterns PS01331 Thymidylate kinase signature. 96 108 - T 30-10-2018 IPR018095 Thymidylate kinase, conserved site GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 CL1_0416 0278c98a31736f675b2c00907baf0e26 205 Pfam PF02223 Thymidylate kinase 5 194 3.5E-55 T 30-10-2018 IPR039430 Thymidylate kinase-like domain KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210 CL1_0416 0278c98a31736f675b2c00907baf0e26 205 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 1 194 3.4E-58 T 30-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 CL1_0984 1aa14fb31ae89322e1a6d2b0f435cff8 311 Pfam PF02272 DHHA1 domain 199 310 9.9E-6 T 30-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 CL1_0984 1aa14fb31ae89322e1a6d2b0f435cff8 311 SUPERFAMILY SSF64182 3 310 4.71E-26 T 30-10-2018 IPR038763 DHH phosphoesterase superfamily CL1_1961 e1161bf6ac6c27579fa62aa5228ced03 313 Gene3D G3DSA:3.100.10.20 1 79 3.3E-18 T 30-10-2018 CL1_1961 e1161bf6ac6c27579fa62aa5228ced03 313 Hamap MF_01470 CRISPR-associated endonuclease Cas1 [cas1]. 2 298 22.67 T 30-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 CL1_1961 e1161bf6ac6c27579fa62aa5228ced03 313 TIGRFAM TIGR00287 cas1: CRISPR-associated endonuclease Cas1 5 307 6.1E-70 T 30-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 CL1_1961 e1161bf6ac6c27579fa62aa5228ced03 313 Gene3D G3DSA:1.20.120.920 82 311 2.9E-53 T 30-10-2018 CL1_1961 e1161bf6ac6c27579fa62aa5228ced03 313 Pfam PF01867 CRISPR associated protein Cas1 5 266 1.2E-58 T 30-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 CL1_1025 7ff7b89e9bd0d8f17678fdc9f73d08c4 486 Pfam PF04415 Protein of unknown function (DUF515) 35 485 2.0E-142 T 30-10-2018 IPR007509 Protein of unknown function DUF515 CL1_1077 56b18e6612b8d6375a4421045d6b6075 1385 Pfam PF00271 Helicase conserved C-terminal domain 1144 1197 3.3E-6 T 30-10-2018 IPR001650 Helicase, C-terminal CL1_1077 56b18e6612b8d6375a4421045d6b6075 1385 SMART SM00490 1105 1198 3.7E-7 T 30-10-2018 IPR001650 Helicase, C-terminal CL1_1077 56b18e6612b8d6375a4421045d6b6075 1385 Gene3D G3DSA:3.40.50.300 1109 1219 1.2E-9 T 30-10-2018 CL1_1077 56b18e6612b8d6375a4421045d6b6075 1385 SUPERFAMILY SSF52540 499 1225 7.88E-17 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_1659 1f4e6c3e84f8c68f3a21bff27e13ae96 202 Pfam PF00881 Nitroreductase family 7 181 6.3E-34 T 30-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 CL1_1659 1f4e6c3e84f8c68f3a21bff27e13ae96 202 Gene3D G3DSA:3.40.109.10 1 199 8.6E-48 T 30-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CL1_1659 1f4e6c3e84f8c68f3a21bff27e13ae96 202 SUPERFAMILY SSF55469 2 201 2.36E-43 T 30-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CL1_1352 0cc71550a1cb00a97934cfad85c38cb2 246 Gene3D G3DSA:3.40.50.620 22 192 3.6E-6 T 30-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CL1_1352 0cc71550a1cb00a97934cfad85c38cb2 246 PIRSF PIRSF006601 1 246 9.2E-85 T 30-10-2018 IPR012096 ATPase, PP-loop, MJ1638-related CL1_1352 0cc71550a1cb00a97934cfad85c38cb2 246 SUPERFAMILY SSF52402 50 190 8.38E-12 T 30-10-2018 CL1_0744 00f0c2329dd1858516d4f402880e0a35 264 SUPERFAMILY SSF56317 1 264 1.96E-75 T 30-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily CL1_0744 00f0c2329dd1858516d4f402880e0a35 264 Pfam PF00795 Carbon-nitrogen hydrolase 2 244 1.5E-59 T 30-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 CL1_0744 00f0c2329dd1858516d4f402880e0a35 264 Gene3D G3DSA:3.60.110.10 1 263 1.4E-103 T 30-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily CL1_1208 f3c7b43b3b54813906b34a628169765a 315 TIGRFAM TIGR00746 arcC: carbamate kinase 2 314 4.3E-144 T 30-10-2018 IPR003964 Carbamate kinase GO:0006525|GO:0008804 KEGG: 00220+2.7.2.2|KEGG: 00230+2.7.2.2|KEGG: 00910+2.7.2.2 CL1_1208 f3c7b43b3b54813906b34a628169765a 315 PRINTS PR01469 Bacterial carbamate kinase signature 44 63 1.9E-68 T 30-10-2018 CL1_1208 f3c7b43b3b54813906b34a628169765a 315 PRINTS PR01469 Bacterial carbamate kinase signature 77 95 1.9E-68 T 30-10-2018 CL1_1208 f3c7b43b3b54813906b34a628169765a 315 PRINTS PR01469 Bacterial carbamate kinase signature 161 180 1.9E-68 T 30-10-2018 CL1_1208 f3c7b43b3b54813906b34a628169765a 315 PRINTS PR01469 Bacterial carbamate kinase signature 184 202 1.9E-68 T 30-10-2018 CL1_1208 f3c7b43b3b54813906b34a628169765a 315 PRINTS PR01469 Bacterial carbamate kinase signature 269 284 1.9E-68 T 30-10-2018 CL1_1208 f3c7b43b3b54813906b34a628169765a 315 PRINTS PR01469 Bacterial carbamate kinase signature 214 229 1.9E-68 T 30-10-2018 CL1_1208 f3c7b43b3b54813906b34a628169765a 315 PRINTS PR01469 Bacterial carbamate kinase signature 112 131 1.9E-68 T 30-10-2018 CL1_1208 f3c7b43b3b54813906b34a628169765a 315 Gene3D G3DSA:3.40.1160.10 1 315 2.5E-136 T 30-10-2018 IPR036393 Acetylglutamate kinase-like superfamily CL1_1208 f3c7b43b3b54813906b34a628169765a 315 Pfam PF00696 Amino acid kinase family 2 295 6.3E-30 T 30-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 CL1_1208 f3c7b43b3b54813906b34a628169765a 315 PIRSF PIRSF000723 1 314 9.3E-140 T 30-10-2018 IPR003964 Carbamate kinase GO:0006525|GO:0008804 KEGG: 00220+2.7.2.2|KEGG: 00230+2.7.2.2|KEGG: 00910+2.7.2.2 CL1_1208 f3c7b43b3b54813906b34a628169765a 315 SUPERFAMILY SSF53633 1 313 2.88E-87 T 30-10-2018 IPR036393 Acetylglutamate kinase-like superfamily CL1_1353 a336a9d48791867fa7ae3baa03a762cf 177 Gene3D G3DSA:3.30.300.130 74 177 4.2E-37 T 30-10-2018 IPR034904 Fe-S cluster assembly domain superfamily CL1_1353 a336a9d48791867fa7ae3baa03a762cf 177 SUPERFAMILY SSF117916 78 175 2.39E-32 T 30-10-2018 IPR034904 Fe-S cluster assembly domain superfamily CL1_1353 a336a9d48791867fa7ae3baa03a762cf 177 Pfam PF01883 Iron-sulfur cluster assembly protein 82 154 7.5E-22 T 30-10-2018 IPR002744 MIP18 family-like CL1_1856 1768ef3cd32c57bbea48858445dd7864 214 Pfam PF04967 HTH DNA binding domain 158 209 7.2E-20 T 30-10-2018 IPR007050 Bacterioopsin activator-type, HTH domain CL1_1856 1768ef3cd32c57bbea48858445dd7864 214 Gene3D G3DSA:1.10.10.10 133 213 5.2E-9 T 30-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CL1_1856 1768ef3cd32c57bbea48858445dd7864 214 SUPERFAMILY SSF88659 155 210 1.77E-8 T 30-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like CL1_0779 46b968a286ec4e4b1590a9a2a941eb20 307 SUPERFAMILY SSF54810 189 307 2.09E-44 T 30-10-2018 CL1_0779 46b968a286ec4e4b1590a9a2a941eb20 307 Pfam PF00958 GMP synthase C terminal domain 218 306 1.3E-33 T 30-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 CL1_0779 46b968a286ec4e4b1590a9a2a941eb20 307 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 5 307 7.5E-151 T 30-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 CL1_0779 46b968a286ec4e4b1590a9a2a941eb20 307 Gene3D G3DSA:3.40.50.620 2 189 5.4E-78 T 30-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CL1_0779 46b968a286ec4e4b1590a9a2a941eb20 307 Pfam PF02540 NAD synthase 5 81 5.1E-7 T 30-10-2018 IPR022310 NAD/GMP synthase CL1_0779 46b968a286ec4e4b1590a9a2a941eb20 307 Gene3D G3DSA:3.30.300.10 190 307 2.5E-52 T 30-10-2018 CL1_0779 46b968a286ec4e4b1590a9a2a941eb20 307 SUPERFAMILY SSF52402 3 224 1.01E-53 T 30-10-2018 CL1_0779 46b968a286ec4e4b1590a9a2a941eb20 307 Hamap MF_00345 GMP synthase [glutamine-hydrolyzing] subunit B [guaAB]. 1 307 45.467 T 30-10-2018 IPR026598 GMP synthase subunit B KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 CL1_1203 f1e2a4e1b7702e6ddf6d0ee05ad4b8f7 141 SUPERFAMILY SSF54909 62 141 4.83E-17 T 30-10-2018 IPR011008 Dimeric alpha-beta barrel CL1_1203 f1e2a4e1b7702e6ddf6d0ee05ad4b8f7 141 Pfam PF13412 Winged helix-turn-helix DNA-binding 2 49 1.1E-14 T 30-10-2018 CL1_1203 f1e2a4e1b7702e6ddf6d0ee05ad4b8f7 141 ProSitePatterns PS00519 AsnC-type HTH domain signature. 20 46 - T 30-10-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site CL1_1203 f1e2a4e1b7702e6ddf6d0ee05ad4b8f7 141 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 18 29 5.9E-16 T 30-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 CL1_1203 f1e2a4e1b7702e6ddf6d0ee05ad4b8f7 141 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 29 48 5.9E-16 T 30-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 CL1_1203 f1e2a4e1b7702e6ddf6d0ee05ad4b8f7 141 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 2 18 5.9E-16 T 30-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 CL1_1203 f1e2a4e1b7702e6ddf6d0ee05ad4b8f7 141 SUPERFAMILY SSF46785 1 62 1.54E-18 T 30-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CL1_1203 f1e2a4e1b7702e6ddf6d0ee05ad4b8f7 141 SMART SM00344 2 108 4.1E-49 T 30-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CL1_1203 f1e2a4e1b7702e6ddf6d0ee05ad4b8f7 141 Gene3D G3DSA:3.30.70.920 65 141 8.3E-20 T 30-10-2018 CL1_1203 f1e2a4e1b7702e6ddf6d0ee05ad4b8f7 141 Pfam PF01037 Lrp/AsnC ligand binding domain 70 138 2.7E-15 T 30-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CL1_1203 f1e2a4e1b7702e6ddf6d0ee05ad4b8f7 141 Gene3D G3DSA:1.10.10.10 1 52 1.3E-21 T 30-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CL1_0225 2c49f66519ac0b40fed2edbf14f1dc13 253 Pfam PF13353 4Fe-4S single cluster domain 29 147 8.5E-7 T 30-10-2018 CL1_0225 2c49f66519ac0b40fed2edbf14f1dc13 253 Gene3D G3DSA:3.20.20.70 4 253 4.8E-26 T 30-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CL1_0225 2c49f66519ac0b40fed2edbf14f1dc13 253 Pfam PF04055 Radical SAM superfamily 31 184 2.8E-14 T 30-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CL1_0225 2c49f66519ac0b40fed2edbf14f1dc13 253 Hamap MF_00917 7-carboxy-7-deazaguanine synthase [queE]. 3 253 37.326 T 30-10-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 CL1_0225 2c49f66519ac0b40fed2edbf14f1dc13 253 SUPERFAMILY SSF102114 33 212 5.76E-13 T 30-10-2018 CL1_1438 a7f185af12ab3267a8b288b75c760c1d 364 Gene3D G3DSA:1.10.10.10 285 362 5.9E-19 T 30-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CL1_1438 a7f185af12ab3267a8b288b75c760c1d 364 Pfam PF01637 ATPase domain predominantly from Archaea 15 247 1.2E-15 T 30-10-2018 IPR011579 ATPase domain GO:0005524 CL1_1438 a7f185af12ab3267a8b288b75c760c1d 364 SUPERFAMILY SSF46785 288 361 1.31E-15 T 30-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CL1_1438 a7f185af12ab3267a8b288b75c760c1d 364 Gene3D G3DSA:3.40.50.300 1 205 4.9E-43 T 30-10-2018 CL1_1438 a7f185af12ab3267a8b288b75c760c1d 364 Gene3D G3DSA:1.10.8.60 207 284 2.0E-23 T 30-10-2018 CL1_1438 a7f185af12ab3267a8b288b75c760c1d 364 SUPERFAMILY SSF52540 2 281 3.43E-44 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_1733 a26f759aabaee7cc35ec741c196f060f 377 SUPERFAMILY SSF141571 34 174 9.42E-42 T 30-10-2018 CL1_1733 a26f759aabaee7cc35ec741c196f060f 377 Gene3D G3DSA:1.10.287.70 249 377 3.8E-14 T 30-10-2018 CL1_1733 a26f759aabaee7cc35ec741c196f060f 377 Gene3D G3DSA:2.160.20.80 4 185 2.0E-46 T 30-10-2018 CL1_1733 a26f759aabaee7cc35ec741c196f060f 377 Pfam PF07885 Ion channel 303 376 3.4E-15 T 30-10-2018 IPR013099 Potassium channel domain CL1_1733 a26f759aabaee7cc35ec741c196f060f 377 Pfam PF00805 Pentapeptide repeats (8 copies) 36 74 2.3E-10 T 30-10-2018 IPR001646 Pentapeptide repeat CL1_1733 a26f759aabaee7cc35ec741c196f060f 377 Pfam PF00805 Pentapeptide repeats (8 copies) 145 179 1.7E-7 T 30-10-2018 IPR001646 Pentapeptide repeat CL1_1733 a26f759aabaee7cc35ec741c196f060f 377 Pfam PF00805 Pentapeptide repeats (8 copies) 75 114 2.2E-12 T 30-10-2018 IPR001646 Pentapeptide repeat CL1_1733 a26f759aabaee7cc35ec741c196f060f 377 SUPERFAMILY SSF81324 295 375 2.09E-14 T 30-10-2018 CL1_1874 4adf1c078457bf4ebc8bc62a23d8fcac 193 SMART SM01022 12 113 8.0E-20 T 30-10-2018 IPR007374 ASCH domain CL1_1874 4adf1c078457bf4ebc8bc62a23d8fcac 193 Pfam PF04266 ASCH domain 15 113 1.3E-21 T 30-10-2018 IPR007374 ASCH domain CL1_1874 4adf1c078457bf4ebc8bc62a23d8fcac 193 SUPERFAMILY SSF88697 9 112 2.98E-20 T 30-10-2018 IPR015947 PUA-like superfamily CL1_1874 4adf1c078457bf4ebc8bc62a23d8fcac 193 Gene3D G3DSA:2.30.130.30 9 112 3.4E-5 T 30-10-2018 CL1_1980 80a993956b809ee3161abf68245b69f8 708 Pfam PF10633 NPCBM-associated, NEW3 domain of alpha-galactosidase 587 663 4.4E-7 T 30-10-2018 IPR018905 Alpha-galactosidase, NEW3 domain CL1_0121 6aca76845f9b3686ba975858d4696e11 537 Gene3D G3DSA:3.30.420.350 95 305 4.4E-64 T 30-10-2018 CL1_0121 6aca76845f9b3686ba975858d4696e11 537 Pfam PF02543 Carbamoyltransferase N-terminus 2 70 1.8E-9 T 30-10-2018 IPR003696 Carbamoyltransferase GO:0003824|GO:0009058 CL1_0121 6aca76845f9b3686ba975858d4696e11 537 Pfam PF02543 Carbamoyltransferase N-terminus 87 312 2.1E-36 T 30-10-2018 IPR003696 Carbamoyltransferase GO:0003824|GO:0009058 CL1_0121 6aca76845f9b3686ba975858d4696e11 537 Gene3D G3DSA:3.90.870.20 330 532 3.9E-73 T 30-10-2018 IPR038152 Carbamoyltransferase, C-terminal domain superfamily CL1_0121 6aca76845f9b3686ba975858d4696e11 537 Gene3D G3DSA:3.30.420.40 9 312 4.4E-64 T 30-10-2018 CL1_0121 6aca76845f9b3686ba975858d4696e11 537 SUPERFAMILY SSF53067 22 315 1.09E-12 T 30-10-2018 CL1_0121 6aca76845f9b3686ba975858d4696e11 537 Pfam PF16861 Carbamoyltransferase C-terminus 364 532 5.8E-63 T 30-10-2018 IPR031730 Carbamoyltransferase, C-terminal CL1_0266 7da6437710e416b2191b6fcc4dc3ec40 439 Gene3D G3DSA:1.20.1530.20 5 417 1.9E-68 T 30-10-2018 IPR038770 Sodium/solute symporter superfamily CL1_0266 7da6437710e416b2191b6fcc4dc3ec40 439 Pfam PF00999 Sodium/hydrogen exchanger family 10 404 8.5E-44 T 30-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 CL1_0499 323bfa2fd01377ee74842e8c45433c21 414 SUPERFAMILY SSF103473 37 411 1.09E-32 T 30-10-2018 IPR036259 MFS transporter superfamily CL1_0499 323bfa2fd01377ee74842e8c45433c21 414 Pfam PF07690 Major Facilitator Superfamily 44 282 3.4E-12 T 30-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CL1_0499 323bfa2fd01377ee74842e8c45433c21 414 Gene3D G3DSA:1.20.1250.20 28 413 7.6E-32 T 30-10-2018 CL1_1536 50b35d78bf0d4bbe18de1028f94005d8 178 Gene3D G3DSA:3.40.1280.10 1 178 1.4E-79 T 30-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CL1_1536 50b35d78bf0d4bbe18de1028f94005d8 178 Hamap MF_00077 tRNA (cytidine(56)-2'-O)-methyltransferase. 1 177 45.212 T 30-10-2018 IPR002845 tRNA ribose 2'-O-methyltransferase, aTrm56 GO:0002128|GO:0005737|GO:0008175 CL1_1536 50b35d78bf0d4bbe18de1028f94005d8 178 ProDom PD016584 UPF0106 MK0803 MM0086 METAL MA3241 UNCHARACTERIZED DOMAIN TA0931 APE2006 ST0333 54 178 9.0E-56 T 30-10-2018 IPR002845 tRNA ribose 2'-O-methyltransferase, aTrm56 GO:0002128|GO:0005737|GO:0008175 CL1_1536 50b35d78bf0d4bbe18de1028f94005d8 178 PIRSF PIRSF016123 1 178 1.8E-87 T 30-10-2018 IPR002845 tRNA ribose 2'-O-methyltransferase, aTrm56 GO:0002128|GO:0005737|GO:0008175 CL1_1536 50b35d78bf0d4bbe18de1028f94005d8 178 Pfam PF01994 tRNA ribose 2'-O-methyltransferase, aTrm56 54 175 2.5E-52 T 30-10-2018 IPR002845 tRNA ribose 2'-O-methyltransferase, aTrm56 GO:0002128|GO:0005737|GO:0008175 CL1_1536 50b35d78bf0d4bbe18de1028f94005d8 178 SUPERFAMILY SSF75217 1 175 1.39E-71 T 30-10-2018 IPR029028 Alpha/beta knot methyltransferases CL1_0839 bb2d6f401fb4173c38df51b7c91ae03f 789 Gene3D G3DSA:3.40.50.12610 485 605 7.0E-13 T 30-10-2018 CL1_0839 bb2d6f401fb4173c38df51b7c91ae03f 789 Pfam PF02516 Oligosaccharyl transferase STT3 subunit 42 529 2.6E-11 T 30-10-2018 IPR003674 Oligosaccharyl transferase, STT3 subunit GO:0004576|GO:0006486|GO:0016020 CL1_1272 08eb48710168ee1d1e09af3bc77a5292 453 Gene3D G3DSA:3.30.2290.10 1 213 8.0E-23 T 30-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal CL1_1272 08eb48710168ee1d1e09af3bc77a5292 453 PIRSF PIRSF004919 1 453 1.5E-161 T 30-10-2018 IPR025502 TldD CL1_1272 08eb48710168ee1d1e09af3bc77a5292 453 Pfam PF01523 Putative modulator of DNA gyrase 19 307 3.2E-65 T 30-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 CL1_1272 08eb48710168ee1d1e09af3bc77a5292 453 SUPERFAMILY SSF111283 1 447 9.68E-117 T 30-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 CL1_0563 f91748714f971c34f1936c901936e6e2 343 Gene3D G3DSA:1.10.600.10 1 343 2.5E-134 T 30-10-2018 IPR008949 Isoprenoid synthase domain superfamily CL1_0563 f91748714f971c34f1936c901936e6e2 343 SUPERFAMILY SSF48576 4 342 1.44E-97 T 30-10-2018 IPR008949 Isoprenoid synthase domain superfamily CL1_0563 f91748714f971c34f1936c901936e6e2 343 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 83 97 - T 30-10-2018 IPR033749 Polyprenyl synthetase, conserved site CL1_0563 f91748714f971c34f1936c901936e6e2 343 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 210 222 - T 30-10-2018 IPR033749 Polyprenyl synthetase, conserved site CL1_0563 f91748714f971c34f1936c901936e6e2 343 Pfam PF00348 Polyprenyl synthetase 33 270 2.1E-70 T 30-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 CL1_0790 14c46ec8257bebd6326fa4d4b0f3f535 229 Gene3D G3DSA:3.60.21.10 15 154 1.3E-11 T 30-10-2018 IPR029052 Metallo-dependent phosphatase-like CL1_0790 14c46ec8257bebd6326fa4d4b0f3f535 229 Pfam PF00149 Calcineurin-like phosphoesterase 17 144 4.2E-7 T 30-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CL1_0790 14c46ec8257bebd6326fa4d4b0f3f535 229 PIRSF PIRSF000887 6 224 1.7E-61 T 30-10-2018 IPR024173 Phosphoesterase, MJ0037 CL1_0790 14c46ec8257bebd6326fa4d4b0f3f535 229 TIGRFAM TIGR00024 SbcD_rel_arch: putative phosphoesterase 6 222 3.4E-47 T 30-10-2018 IPR004376 Conserved hypothetical protein CHP00024, phosphoesterase-like CL1_0790 14c46ec8257bebd6326fa4d4b0f3f535 229 SUPERFAMILY SSF56300 17 130 4.0E-15 T 30-10-2018 CL1_1377 439a9926c6e18d04d99da1f8af8075a5 411 SUPERFAMILY SSF103473 24 409 1.44E-56 T 30-10-2018 IPR036259 MFS transporter superfamily CL1_1377 439a9926c6e18d04d99da1f8af8075a5 411 Gene3D G3DSA:1.20.1250.20 240 410 4.8E-28 T 30-10-2018 CL1_1377 439a9926c6e18d04d99da1f8af8075a5 411 Gene3D G3DSA:1.20.1250.20 20 239 6.4E-32 T 30-10-2018 CL1_1377 439a9926c6e18d04d99da1f8af8075a5 411 PRINTS PR01035 Tetracycline resistance protein signature 361 384 1.5E-7 T 30-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CL1_1377 439a9926c6e18d04d99da1f8af8075a5 411 PRINTS PR01035 Tetracycline resistance protein signature 95 119 1.5E-7 T 30-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CL1_1377 439a9926c6e18d04d99da1f8af8075a5 411 PRINTS PR01035 Tetracycline resistance protein signature 300 321 1.5E-7 T 30-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CL1_1377 439a9926c6e18d04d99da1f8af8075a5 411 PRINTS PR01035 Tetracycline resistance protein signature 37 53 1.5E-7 T 30-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CL1_1377 439a9926c6e18d04d99da1f8af8075a5 411 PRINTS PR01035 Tetracycline resistance protein signature 151 173 1.5E-7 T 30-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CL1_1377 439a9926c6e18d04d99da1f8af8075a5 411 Pfam PF07690 Major Facilitator Superfamily 32 269 5.3E-27 T 30-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CL1_0420 6bdc237dcea8225eb762f100412620fd 440 Pfam PF07690 Major Facilitator Superfamily 12 273 9.6E-35 T 30-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CL1_0420 6bdc237dcea8225eb762f100412620fd 440 SUPERFAMILY SSF103473 8 428 2.09E-64 T 30-10-2018 IPR036259 MFS transporter superfamily CL1_0420 6bdc237dcea8225eb762f100412620fd 440 Gene3D G3DSA:1.20.1250.20 2 197 5.5E-31 T 30-10-2018 CL1_0420 6bdc237dcea8225eb762f100412620fd 440 Gene3D G3DSA:1.20.1250.20 223 425 5.0E-25 T 30-10-2018 CL1_0375 dc71904365127b31cbc9b51d56a28df3 261 TIGRFAM TIGR01877 cas_cas6: CRISPR-associated endoribonuclease Cas6 44 239 7.5E-47 T 30-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 CL1_0375 dc71904365127b31cbc9b51d56a28df3 261 PIRSF PIRSF005054 2 244 9.1E-64 T 30-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 CL1_0375 dc71904365127b31cbc9b51d56a28df3 261 Gene3D G3DSA:3.30.70.1890 1 123 6.6E-37 T 30-10-2018 CL1_0375 dc71904365127b31cbc9b51d56a28df3 261 Pfam PF01881 CRISPR associated protein Cas6 96 239 5.7E-33 T 30-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 CL1_0375 dc71904365127b31cbc9b51d56a28df3 261 Gene3D G3DSA:3.30.70.1900 124 242 4.5E-36 T 30-10-2018 CL1_1356 1e5703ba59cf95e050aeeffb4c54d87f 267 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 143 151 1.6E-11 T 30-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CL1_1356 1e5703ba59cf95e050aeeffb4c54d87f 267 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 91 102 1.6E-11 T 30-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CL1_1356 1e5703ba59cf95e050aeeffb4c54d87f 267 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 164 183 1.6E-11 T 30-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CL1_1356 1e5703ba59cf95e050aeeffb4c54d87f 267 Gene3D G3DSA:3.40.50.720 3 266 1.3E-72 T 30-10-2018 CL1_1356 1e5703ba59cf95e050aeeffb4c54d87f 267 SUPERFAMILY SSF51735 16 265 3.8E-72 T 30-10-2018 IPR036291 NAD(P)-binding domain superfamily CL1_1356 1e5703ba59cf95e050aeeffb4c54d87f 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 228 248 4.8E-40 T 30-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CL1_1356 1e5703ba59cf95e050aeeffb4c54d87f 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 184 201 4.8E-40 T 30-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CL1_1356 1e5703ba59cf95e050aeeffb4c54d87f 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 91 102 4.8E-40 T 30-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CL1_1356 1e5703ba59cf95e050aeeffb4c54d87f 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 19 36 4.8E-40 T 30-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CL1_1356 1e5703ba59cf95e050aeeffb4c54d87f 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 137 153 4.8E-40 T 30-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CL1_1356 1e5703ba59cf95e050aeeffb4c54d87f 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 183 4.8E-40 T 30-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CL1_1356 1e5703ba59cf95e050aeeffb4c54d87f 267 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 24 264 2.7E-57 T 30-10-2018 CL1_0026 e0146f44dde76ea814eeade658c1c997 596 Pfam PF16286 Domain of unknown function (DUF4932) 30 201 1.4E-11 T 30-10-2018 IPR032560 Protein of unknown function DUF4932 CL1_1886 57a433c7c54196fc7881f3d0b9e58d48 126 Pfam PF02641 Uncharacterized ACR, COG1993 11 104 3.1E-37 T 30-10-2018 IPR003793 Domain of unknown function DUF190 CL1_1886 57a433c7c54196fc7881f3d0b9e58d48 126 Gene3D G3DSA:3.30.70.120 1 126 1.1E-55 T 30-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal CL1_1886 57a433c7c54196fc7881f3d0b9e58d48 126 SUPERFAMILY SSF54913 8 104 1.11E-33 T 30-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta CL1_0149 4d77dde88a78060426c5806f6c02f1e7 445 Pfam PF01458 Uncharacterized protein family (UPF0051) 194 417 2.6E-52 T 30-10-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 CL1_0149 4d77dde88a78060426c5806f6c02f1e7 445 SUPERFAMILY SSF101960 18 441 2.09E-101 T 30-10-2018 IPR037284 SUF system FeS cluster assembly, SufBD superfamily CL1_0880 aa8d10a90f60942319725ef22c7155a5 361 Pfam PF13394 4Fe-4S single cluster domain 31 121 1.2E-5 T 30-10-2018 CL1_0880 aa8d10a90f60942319725ef22c7155a5 361 Pfam PF04055 Radical SAM superfamily 33 185 4.8E-14 T 30-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CL1_0880 aa8d10a90f60942319725ef22c7155a5 361 Gene3D G3DSA:3.20.20.70 24 286 7.1E-17 T 30-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CL1_0880 aa8d10a90f60942319725ef22c7155a5 361 SUPERFAMILY SSF102114 27 206 2.22E-23 T 30-10-2018 CL1_1127 dd2db31dab176d66f24246f857aeb7b8 160 Gene3D G3DSA:1.20.1260.10 8 157 3.7E-30 T 30-10-2018 IPR012347 Ferritin-like CL1_1127 dd2db31dab176d66f24246f857aeb7b8 160 Pfam PF02915 Rubrerythrin 18 154 2.1E-14 T 30-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 CL1_1127 dd2db31dab176d66f24246f857aeb7b8 160 SUPERFAMILY SSF47240 14 158 2.11E-27 T 30-10-2018 IPR009078 Ferritin-like superfamily CL1_1426 c4e151c6eed62c054851a634dc44255a 403 Pfam PF00999 Sodium/hydrogen exchanger family 29 382 2.3E-27 T 30-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 CL1_1426 c4e151c6eed62c054851a634dc44255a 403 Gene3D G3DSA:1.20.1530.20 22 399 3.8E-41 T 30-10-2018 IPR038770 Sodium/solute symporter superfamily CL1_0131 49d07c364158130c049573dc5d6611a5 69 Gene3D G3DSA:2.30.30.240 2 69 5.2E-7 T 30-10-2018 CL1_0131 49d07c364158130c049573dc5d6611a5 69 Pfam PF05239 PRC-barrel domain 2 68 1.2E-12 T 30-10-2018 IPR027275 PRC-barrel domain CL1_0131 49d07c364158130c049573dc5d6611a5 69 SUPERFAMILY SSF50346 1 66 2.2E-14 T 30-10-2018 IPR011033 PRC-barrel-like superfamily CL1_1410 690fb0d804f04f237654a769907a0c86 567 Pfam PF04458 Protein of unknown function (DUF505) 306 566 1.7E-78 T 30-10-2018 IPR007548 Protein of unknown function DUF505 CL1_1410 690fb0d804f04f237654a769907a0c86 567 Pfam PF04458 Protein of unknown function (DUF505) 1 301 4.9E-75 T 30-10-2018 IPR007548 Protein of unknown function DUF505 CL1_1750 ca19100370f75a172328605a6c85fc83 137 Gene3D G3DSA:3.40.50.1010 2 131 1.7E-30 T 30-10-2018 CL1_1750 ca19100370f75a172328605a6c85fc83 137 Pfam PF01850 PIN domain 3 127 1.6E-13 T 30-10-2018 IPR002716 PIN domain CL1_1750 ca19100370f75a172328605a6c85fc83 137 SUPERFAMILY SSF88723 3 135 1.51E-21 T 30-10-2018 IPR029060 PIN-like domain superfamily CL1_1785 76f76363ee965e69f84e0c1be2ba1ddb 204 SUPERFAMILY SSF53146 1 119 5.1E-29 T 30-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily CL1_1785 76f76363ee965e69f84e0c1be2ba1ddb 204 Gene3D G3DSA:3.30.420.130 1 117 1.3E-28 T 30-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily CL1_1785 76f76363ee965e69f84e0c1be2ba1ddb 204 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 13 107 4.4E-22 T 30-10-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis CL1_1443 a3e3bf1fe7e63ab2238ba129446d161e 212 Pfam PF03192 Pyrococcus protein of unknown function, DUF257 13 197 3.4E-15 T 30-10-2018 IPR005489 Protein of unknown function DUF257 CL1_1443 a3e3bf1fe7e63ab2238ba129446d161e 212 Gene3D G3DSA:3.40.50.11570 7 210 2.3E-17 T 30-10-2018 CL1_1043 7686f7e0def7fd1ee86fbff621639a55 179 Gene3D G3DSA:3.40.220.10 1 179 1.9E-54 T 30-10-2018 CL1_1043 7686f7e0def7fd1ee86fbff621639a55 179 SUPERFAMILY SSF52949 4 177 4.04E-51 T 30-10-2018 CL1_1043 7686f7e0def7fd1ee86fbff621639a55 179 SMART SM00506 3 146 1.8E-52 T 30-10-2018 IPR002589 Macro domain CL1_1043 7686f7e0def7fd1ee86fbff621639a55 179 Pfam PF01661 Macro domain 20 145 1.6E-34 T 30-10-2018 IPR002589 Macro domain CL1_1862 914009c32c447b3f6ed0b12f6025718d 215 Gene3D G3DSA:3.30.1020.10 145 215 3.5E-33 T 30-10-2018 CL1_1862 914009c32c447b3f6ed0b12f6025718d 215 Hamap MF_00401 Peroxiredoxin. 2 215 51.215 T 30-10-2018 IPR022915 Peroxiredoxin, TDXH subfamily GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CL1_1862 914009c32c447b3f6ed0b12f6025718d 215 SUPERFAMILY SSF52833 1 215 2.86E-64 T 30-10-2018 IPR036249 Thioredoxin-like superfamily CL1_1862 914009c32c447b3f6ed0b12f6025718d 215 PIRSF PIRSF000239 1 214 1.4E-70 T 30-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CL1_1862 914009c32c447b3f6ed0b12f6025718d 215 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 155 195 2.0E-9 T 30-10-2018 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CL1_1862 914009c32c447b3f6ed0b12f6025718d 215 Pfam PF00578 AhpC/TSA family 4 134 8.8E-33 T 30-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CL1_1862 914009c32c447b3f6ed0b12f6025718d 215 Gene3D G3DSA:3.40.30.10 1 144 1.2E-45 T 30-10-2018 CL1_1680 ccfc30b62fb84e1d0c035498836fc350 411 Gene3D G3DSA:3.40.50.1260 9 397 3.1E-138 T 30-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CL1_1680 ccfc30b62fb84e1d0c035498836fc350 411 PIRSF PIRSF000724 1 407 1.5E-130 T 30-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CL1_1680 ccfc30b62fb84e1d0c035498836fc350 411 Pfam PF00162 Phosphoglycerate kinase 5 389 9.8E-107 T 30-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CL1_1680 ccfc30b62fb84e1d0c035498836fc350 411 SUPERFAMILY SSF53748 2 400 3.77E-116 T 30-10-2018 IPR036043 Phosphoglycerate kinase superfamily GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CL1_1680 ccfc30b62fb84e1d0c035498836fc350 411 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 6 400 34.851 T 30-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CL1_1680 ccfc30b62fb84e1d0c035498836fc350 411 PRINTS PR00477 Phosphoglycerate kinase family signature 354 365 8.7E-65 T 30-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CL1_1680 ccfc30b62fb84e1d0c035498836fc350 411 PRINTS PR00477 Phosphoglycerate kinase family signature 321 346 8.7E-65 T 30-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CL1_1680 ccfc30b62fb84e1d0c035498836fc350 411 PRINTS PR00477 Phosphoglycerate kinase family signature 170 192 8.7E-65 T 30-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CL1_1680 ccfc30b62fb84e1d0c035498836fc350 411 PRINTS PR00477 Phosphoglycerate kinase family signature 105 120 8.7E-65 T 30-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CL1_1680 ccfc30b62fb84e1d0c035498836fc350 411 PRINTS PR00477 Phosphoglycerate kinase family signature 29 51 8.7E-65 T 30-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CL1_1680 ccfc30b62fb84e1d0c035498836fc350 411 PRINTS PR00477 Phosphoglycerate kinase family signature 140 162 8.7E-65 T 30-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CL1_1680 ccfc30b62fb84e1d0c035498836fc350 411 PRINTS PR00477 Phosphoglycerate kinase family signature 376 393 8.7E-65 T 30-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CL1_1680 ccfc30b62fb84e1d0c035498836fc350 411 PRINTS PR00477 Phosphoglycerate kinase family signature 193 212 8.7E-65 T 30-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CL1_1680 ccfc30b62fb84e1d0c035498836fc350 411 PRINTS PR00477 Phosphoglycerate kinase family signature 8 24 8.7E-65 T 30-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CL1_1680 ccfc30b62fb84e1d0c035498836fc350 411 ProSitePatterns PS00111 Phosphoglycerate kinase signature. 13 23 - T 30-10-2018 IPR015911 Phosphoglycerate kinase, conserved site GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CL1_1680 ccfc30b62fb84e1d0c035498836fc350 411 Gene3D G3DSA:3.40.50.1260 189 390 3.1E-138 T 30-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CL1_0333 159a50e44ba500884e60d969f696f2a8 289 Pfam PF12679 ABC-2 family transporter protein 7 288 2.6E-40 T 30-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 CL1_0377 4cfc107f700b642a76b0e339101a4468 362 TIGRFAM TIGR01875 cas_MJ0381: CRISPR-associated autoregulator DevR family 20 268 9.4E-39 T 30-10-2018 IPR010154 CRISPR-associated protein Cas7/Cst2/DevR CL1_0377 4cfc107f700b642a76b0e339101a4468 362 Pfam PF01905 CRISPR-associated negative auto-regulator DevR/Csa2 16 255 1.3E-14 T 30-10-2018 IPR010154 CRISPR-associated protein Cas7/Cst2/DevR CL1_0377 4cfc107f700b642a76b0e339101a4468 362 TIGRFAM TIGR02585 cas_Cst2_DevR: CRISPR-associated protein Cas7/Cst2/DevR, subtype I-B/TNEAP 14 351 5.5E-81 T 30-10-2018 IPR013414 CRISPR-associated protein Cas7, subtype I-B/Tneap CL1_1013 8973a29e2ee11553ac1f5e145018a28f 277 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 232 245 - T 30-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 CL1_1013 8973a29e2ee11553ac1f5e145018a28f 277 Gene3D G3DSA:3.40.1190.20 2 276 2.1E-61 T 30-10-2018 IPR029056 Ribokinase-like CL1_1013 8973a29e2ee11553ac1f5e145018a28f 277 PRINTS PR00990 Ribokinase signature 23 42 4.3E-6 T 30-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CL1_1013 8973a29e2ee11553ac1f5e145018a28f 277 PRINTS PR00990 Ribokinase signature 162 177 4.3E-6 T 30-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CL1_1013 8973a29e2ee11553ac1f5e145018a28f 277 PRINTS PR00990 Ribokinase signature 201 212 4.3E-6 T 30-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CL1_1013 8973a29e2ee11553ac1f5e145018a28f 277 SUPERFAMILY SSF53613 1 275 2.34E-56 T 30-10-2018 IPR029056 Ribokinase-like CL1_1013 8973a29e2ee11553ac1f5e145018a28f 277 Pfam PF00294 pfkB family carbohydrate kinase 4 274 2.7E-41 T 30-10-2018 IPR011611 Carbohydrate kinase PfkB CL1_1872 eeb91a3c6be6733d88ee6629f17ca7d3 136 Pfam PF12646 Domain of unknown function (DUF3783) 58 113 5.0E-16 T 30-10-2018 IPR016621 Uncharacterised conserved protein UCP014543 CL1_1872 eeb91a3c6be6733d88ee6629f17ca7d3 136 PIRSF PIRSF014543 1 123 6.8E-40 T 30-10-2018 IPR016621 Uncharacterised conserved protein UCP014543 CL1_0451 6d465ceb39df7b4b67e5e137f44479c6 398 Gene3D G3DSA:3.40.640.10 53 294 4.2E-142 T 30-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 CL1_0451 6d465ceb39df7b4b67e5e137f44479c6 398 Gene3D G3DSA:3.90.1150.10 24 390 4.2E-142 T 30-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 CL1_0451 6d465ceb39df7b4b67e5e137f44479c6 398 SUPERFAMILY SSF53383 12 394 1.6E-106 T 30-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase CL1_0451 6d465ceb39df7b4b67e5e137f44479c6 398 Pfam PF00155 Aminotransferase class I and II 31 381 6.6E-60 T 30-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CL1_0497 a75a02ed282446f3e53d63c75e7dbf3c 80 Pfam PF14358 Domain of unknown function (DUF4405) 9 68 4.4E-9 T 30-10-2018 IPR025517 Domain of unknown function DUF4405 CL1_0484 3a2871207f14c72b30a543379f3a80c9 198 Pfam PF12804 MobA-like NTP transferase domain 3 141 7.0E-30 T 30-10-2018 IPR025877 MobA-like NTP transferase CL1_0484 3a2871207f14c72b30a543379f3a80c9 198 Gene3D G3DSA:3.90.550.10 4 197 8.3E-44 T 30-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases CL1_0484 3a2871207f14c72b30a543379f3a80c9 198 Hamap MF_00316 Molybdenum cofactor guanylyltransferase [mobA]. 1 188 19.907 T 30-10-2018 IPR013482 Molybdenum cofactor guanylyltransferase GO:0003824|GO:0006777 KEGG: 00790+2.7.7.77|MetaCyc: PWY-5964|MetaCyc: PWY-7639 CL1_0484 3a2871207f14c72b30a543379f3a80c9 198 SUPERFAMILY SSF53448 1 185 8.11E-30 T 30-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases CL1_0926 c7328cf188475b26ed9df7b7e16c6458 422 SUPERFAMILY SSF161098 210 405 1.2E-14 T 30-10-2018 IPR035906 MetI-like superfamily CL1_0926 c7328cf188475b26ed9df7b7e16c6458 422 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 229 417 2.0E-8 T 30-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 CL1_0926 c7328cf188475b26ed9df7b7e16c6458 422 Gene3D G3DSA:1.10.3720.10 206 417 4.2E-12 T 30-10-2018 IPR035906 MetI-like superfamily CL1_2040 36993dcc3376050da7c376cb5c187642 267 Pfam PF02457 DisA bacterial checkpoint controller nucleotide-binding 133 255 3.1E-22 T 30-10-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal CL1_2040 36993dcc3376050da7c376cb5c187642 267 Hamap MF_00840 Diadenylate cyclase [dacZ]. 8 266 34.482 T 30-10-2018 IPR014499 Diadenylate cyclase, DacZ-type CL1_2040 36993dcc3376050da7c376cb5c187642 267 Gene3D G3DSA:3.40.1700.10 167 265 4.1E-14 T 30-10-2018 IPR036888 DNA integrity scanning protein, DisA, N-terminal domain superfamily CL1_2040 36993dcc3376050da7c376cb5c187642 267 SUPERFAMILY SSF143597 108 260 2.48E-30 T 30-10-2018 IPR036888 DNA integrity scanning protein, DisA, N-terminal domain superfamily CL1_2040 36993dcc3376050da7c376cb5c187642 267 PIRSF PIRSF019073 7 267 1.6E-75 T 30-10-2018 IPR014499 Diadenylate cyclase, DacZ-type CL1_1083 d537853309418f015d2cda13faca7459 226 Gene3D G3DSA:3.20.20.70 1 225 3.5E-94 T 30-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CL1_1083 d537853309418f015d2cda13faca7459 226 ProSitePatterns PS00171 Triosephosphate isomerase active site. 142 152 - T 30-10-2018 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CL1_1083 d537853309418f015d2cda13faca7459 226 Hamap MF_00147_A Triosephosphate isomerase [tpiA]. 6 225 43.915 T 30-10-2018 IPR022891 Triosephosphate isomerase, archaeal GO:0004807|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003 CL1_1083 d537853309418f015d2cda13faca7459 226 SUPERFAMILY SSF51351 4 223 5.11E-47 T 30-10-2018 IPR035990 Triosephosphate isomerase superfamily GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CL1_1083 d537853309418f015d2cda13faca7459 226 Pfam PF00121 Triosephosphate isomerase 8 112 6.7E-10 T 30-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CL1_1083 d537853309418f015d2cda13faca7459 226 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 8 212 9.0E-62 T 30-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CL1_1083 d537853309418f015d2cda13faca7459 226 Pfam PF05690 Thiazole biosynthesis protein ThiG 167 216 5.8E-6 T 30-10-2018 IPR033983 Thiazole synthase ThiG KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 CL1_1084 bdb753865daf3dfd283f5e812b4166da 189 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 8 62 1.9E-12 T 30-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CL1_1084 bdb753865daf3dfd283f5e812b4166da 189 Pfam PF01467 Cytidylyltransferase-like 9 145 2.9E-14 T 30-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CL1_1084 bdb753865daf3dfd283f5e812b4166da 189 Gene3D G3DSA:3.40.50.620 6 154 4.4E-41 T 30-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CL1_1084 bdb753865daf3dfd283f5e812b4166da 189 SUPERFAMILY SSF52374 3 147 7.04E-20 T 30-10-2018 CL1_0965 b47034d21a20d5a919867119642995ef 380 Pfam PF00999 Sodium/hydrogen exchanger family 9 376 1.7E-68 T 30-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 CL1_0965 b47034d21a20d5a919867119642995ef 380 Gene3D G3DSA:1.20.1530.20 1 379 7.2E-101 T 30-10-2018 IPR038770 Sodium/solute symporter superfamily CL1_0883 c59e01264b5a37d28c8eb2e461bdb9d6 340 SUPERFAMILY SSF46785 3 92 1.84E-9 T 30-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CL1_0883 c59e01264b5a37d28c8eb2e461bdb9d6 340 SUPERFAMILY SSF159071 255 339 1.26E-19 T 30-10-2018 CL1_0883 c59e01264b5a37d28c8eb2e461bdb9d6 340 Pfam PF11495 Archaeal transcriptional regulator TrmB 112 338 5.8E-52 T 30-10-2018 IPR021586 Transcription regulator TrmB, C-terminal CL1_0883 c59e01264b5a37d28c8eb2e461bdb9d6 340 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 10 77 2.6E-25 T 30-10-2018 IPR002831 Transcription regulator TrmB, N-terminal CL1_0883 c59e01264b5a37d28c8eb2e461bdb9d6 340 Gene3D G3DSA:1.10.10.10 2 100 2.0E-29 T 30-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CL1_1412 5a548d7325b500a300011f45e34dfd82 332 Gene3D G3DSA:3.40.800.20 4 318 6.8E-79 T 30-10-2018 IPR037138 Histone deacetylase domain superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CL1_1412 5a548d7325b500a300011f45e34dfd82 332 PRINTS PR01270 Histone deacetylase superfamily signature 154 169 7.2E-11 T 30-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CL1_1412 5a548d7325b500a300011f45e34dfd82 332 PRINTS PR01270 Histone deacetylase superfamily signature 122 145 7.2E-11 T 30-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CL1_1412 5a548d7325b500a300011f45e34dfd82 332 PRINTS PR01270 Histone deacetylase superfamily signature 237 247 7.2E-11 T 30-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CL1_1412 5a548d7325b500a300011f45e34dfd82 332 Pfam PF00850 Histone deacetylase domain 20 286 1.5E-63 T 30-10-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CL1_1412 5a548d7325b500a300011f45e34dfd82 332 SUPERFAMILY SSF52768 4 330 8.15E-85 T 30-10-2018 IPR023696 Ureohydrolase domain superfamily CL1_1769 160a44929216bf61dc6266a5fc137270 489 SUPERFAMILY SSF103473 16 479 1.7E-65 T 30-10-2018 IPR036259 MFS transporter superfamily CL1_1769 160a44929216bf61dc6266a5fc137270 489 Gene3D G3DSA:1.20.1720.10 19 223 2.5E-47 T 30-10-2018 CL1_1769 160a44929216bf61dc6266a5fc137270 489 Pfam PF07690 Major Facilitator Superfamily 27 420 2.6E-48 T 30-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CL1_1769 160a44929216bf61dc6266a5fc137270 489 Gene3D G3DSA:1.20.1250.20 264 478 2.3E-12 T 30-10-2018 CL1_1413 553564b3a5ccd24ffb35c9813ca4d1ca 439 Pfam PF00999 Sodium/hydrogen exchanger family 13 409 7.1E-51 T 30-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 CL1_1413 553564b3a5ccd24ffb35c9813ca4d1ca 439 Gene3D G3DSA:1.20.1530.20 6 418 8.7E-23 T 30-10-2018 IPR038770 Sodium/solute symporter superfamily CL1_0171 42ee4eeae4b503f146ba29f09c7a5f3b 61 Pfam PF04021 Class III signal peptide 3 27 4.0E-7 T 30-10-2018 IPR007166 Class III signal peptide motif CL1_1877 c8e9829f2f846779d29962eee7e89628 426 Pfam PF07690 Major Facilitator Superfamily 19 383 9.3E-44 T 30-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CL1_1877 c8e9829f2f846779d29962eee7e89628 426 Gene3D G3DSA:1.20.1250.20 7 426 5.2E-81 T 30-10-2018 CL1_1877 c8e9829f2f846779d29962eee7e89628 426 SUPERFAMILY SSF103473 5 425 4.19E-79 T 30-10-2018 IPR036259 MFS transporter superfamily CL1_1877 c8e9829f2f846779d29962eee7e89628 426 ProSitePatterns PS00217 Sugar transport proteins signature 2. 114 139 - T 30-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CL1_1562 b7bfbba2b947051c742086f03297d19d 71 SUPERFAMILY SSF50182 6 71 1.37E-27 T 30-10-2018 IPR010920 LSM domain superfamily CL1_1562 b7bfbba2b947051c742086f03297d19d 71 Gene3D G3DSA:2.30.30.100 2 71 1.9E-30 T 30-10-2018 CL1_0153 15cddf154141233b867c353a0c119e93 127 SUPERFAMILY SSF55298 2 127 4.24E-44 T 30-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 CL1_0153 15cddf154141233b867c353a0c119e93 127 Gene3D G3DSA:3.30.1330.40 1 127 1.6E-51 T 30-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 CL1_0153 15cddf154141233b867c353a0c119e93 127 ProSitePatterns PS01094 Uncharacterized protein family UPF0076 signature. 103 121 - T 30-10-2018 IPR019897 RidA, conserved site Reactome: R-HSA-8849175 CL1_0153 15cddf154141233b867c353a0c119e93 127 Pfam PF01042 Endoribonuclease L-PSP 9 126 6.8E-42 T 30-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 CL1_0153 15cddf154141233b867c353a0c119e93 127 TIGRFAM TIGR00004 TIGR00004: reactive intermediate/imine deaminase 3 126 1.2E-49 T 30-10-2018 IPR006056 RidA family Reactome: R-HSA-8849175 CL1_1151 7ce459061a952108c3e14a4c513b34d5 390 Gene3D G3DSA:1.10.645.10 2 385 1.0E-93 T 30-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CL1_1151 7ce459061a952108c3e14a4c513b34d5 390 ProSitePatterns PS00507 Nickel-dependent hydrogenases large subunit signature 1. 39 64 - T 30-10-2018 IPR018194 Nickel-dependent hydrogenase, large subunit, nickel binding site GO:0008901|GO:0016151|GO:0055114 CL1_1151 7ce459061a952108c3e14a4c513b34d5 390 Pfam PF00374 Nickel-dependent hydrogenase 39 109 4.4E-15 T 30-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 CL1_1151 7ce459061a952108c3e14a4c513b34d5 390 Pfam PF00374 Nickel-dependent hydrogenase 292 385 6.4E-7 T 30-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 CL1_1151 7ce459061a952108c3e14a4c513b34d5 390 SUPERFAMILY SSF56762 3 385 1.57E-76 T 30-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CL1_1414 c393360531193ff6e2327feb9d528efe 202 TIGRFAM TIGR03334 IOR_beta: indolepyruvate ferredoxin oxidoreductase, beta subunit 4 194 8.7E-93 T 30-10-2018 IPR017719 Indolepyruvate ferredoxin oxidoreductase, beta subunit GO:0043805|GO:0055114 CL1_1414 c393360531193ff6e2327feb9d528efe 202 SUPERFAMILY SSF53323 4 199 4.32E-44 T 30-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 CL1_1414 c393360531193ff6e2327feb9d528efe 202 Gene3D G3DSA:3.40.920.10 1 201 3.8E-50 T 30-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 CL1_1414 c393360531193ff6e2327feb9d528efe 202 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 12 193 9.7E-39 T 30-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 CL1_1000 aec60354d15db7e68540252068b4758a 424 Gene3D G3DSA:3.40.50.300 69 154 5.2E-7 T 30-10-2018 CL1_1000 aec60354d15db7e68540252068b4758a 424 Pfam PF13173 AAA domain 35 167 1.1E-37 T 30-10-2018 CL1_1000 aec60354d15db7e68540252068b4758a 424 Pfam PF13635 Domain of unknown function (DUF4143) 227 366 6.8E-9 T 30-10-2018 IPR025420 Domain of unknown function DUF4143 CL1_1000 aec60354d15db7e68540252068b4758a 424 SUPERFAMILY SSF52540 29 229 3.97E-22 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_0049 86c33f18b8234be09a94b2c92143d8fd 349 Gene3D G3DSA:3.90.550.10 28 240 7.3E-47 T 30-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases CL1_0049 86c33f18b8234be09a94b2c92143d8fd 349 Pfam PF00535 Glycosyl transferase family 2 40 200 2.9E-35 T 30-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CL1_0049 86c33f18b8234be09a94b2c92143d8fd 349 SUPERFAMILY SSF53448 36 256 2.15E-54 T 30-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases CL1_0437 3a6dc6fd33ecec7cf4f6e0895ea80d3d 501 Pfam PF02347 Glycine cleavage system P-protein 33 309 2.1E-11 T 30-10-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 CL1_0437 3a6dc6fd33ecec7cf4f6e0895ea80d3d 501 Hamap MF_00713 Probable glycine dehydrogenase (decarboxylating) subunit 2 [gcvPB]. 10 489 60.423 T 30-10-2018 IPR023012 Probable glycine dehydrogenase (decarboxylating) subunit 2 GO:0004375|GO:0019464 KEGG: 00260+1.4.4.2 CL1_0437 3a6dc6fd33ecec7cf4f6e0895ea80d3d 501 SUPERFAMILY SSF53383 11 487 8.8E-122 T 30-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase CL1_0437 3a6dc6fd33ecec7cf4f6e0895ea80d3d 501 Gene3D G3DSA:3.90.1150.10 339 474 3.4E-44 T 30-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 CL1_0437 3a6dc6fd33ecec7cf4f6e0895ea80d3d 501 Gene3D G3DSA:3.40.640.10 86 322 3.9E-60 T 30-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 CL1_1830 a5b69b941eaaf8f4472e0b32ef0a2b73 170 SUPERFAMILY SSF47240 14 149 4.43E-18 T 30-10-2018 IPR009078 Ferritin-like superfamily CL1_1830 a5b69b941eaaf8f4472e0b32ef0a2b73 170 Pfam PF02915 Rubrerythrin 15 143 6.6E-11 T 30-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 CL1_1830 a5b69b941eaaf8f4472e0b32ef0a2b73 170 Gene3D G3DSA:1.20.1260.10 1 148 1.2E-26 T 30-10-2018 IPR012347 Ferritin-like CL1_0234 8e35ead48a69693db3cbfe2f5c23b559 327 Pfam PF02272 DHHA1 domain 234 318 3.0E-12 T 30-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 CL1_0234 8e35ead48a69693db3cbfe2f5c23b559 327 SUPERFAMILY SSF64182 18 306 6.54E-50 T 30-10-2018 IPR038763 DHH phosphoesterase superfamily CL1_0234 8e35ead48a69693db3cbfe2f5c23b559 327 Gene3D G3DSA:3.10.310.40 220 321 8.3E-7 T 30-10-2018 CL1_0234 8e35ead48a69693db3cbfe2f5c23b559 327 Gene3D G3DSA:3.90.1640.10 6 198 1.4E-37 T 30-10-2018 CL1_0234 8e35ead48a69693db3cbfe2f5c23b559 327 Pfam PF01368 DHH family 19 159 1.1E-10 T 30-10-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CL1_0360 d003f718e0d57a8716b5386e33b5f9d5 206 Pfam PF01966 HD domain 35 137 2.7E-20 T 30-10-2018 IPR006674 HD domain CL1_0360 d003f718e0d57a8716b5386e33b5f9d5 206 SUPERFAMILY SSF109604 14 205 2.62E-61 T 30-10-2018 CL1_0360 d003f718e0d57a8716b5386e33b5f9d5 206 TIGRFAM TIGR00277 HDIG: HDIG domain 33 95 3.4E-10 T 30-10-2018 IPR006675 HDIG domain CL1_0360 d003f718e0d57a8716b5386e33b5f9d5 206 SMART SM00471 30 147 5.8E-11 T 30-10-2018 IPR003607 HD/PDEase domain CL1_0360 d003f718e0d57a8716b5386e33b5f9d5 206 Gene3D G3DSA:1.10.3210.50 14 206 3.8E-64 T 30-10-2018 CL1_1019 4c707c62bcd672ba2e06f13ec91d4763 164 Pfam PF09891 Uncharacterized protein conserved in archaea (DUF2118) 3 163 1.2E-50 T 30-10-2018 IPR019217 Protein of unknown function DUF2118 CL1_1019 4c707c62bcd672ba2e06f13ec91d4763 164 Gene3D G3DSA:2.40.50.100 97 163 8.3E-31 T 30-10-2018 CL1_1019 4c707c62bcd672ba2e06f13ec91d4763 164 PIRSF PIRSF019115 1 164 8.4E-67 T 30-10-2018 IPR019217 Protein of unknown function DUF2118 CL1_0530 98f55ad71f3b91987bc18e8a2abef670 125 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 13 125 9.475 T 30-10-2018 IPR022907 VapC family GO:0004540 CL1_0530 98f55ad71f3b91987bc18e8a2abef670 125 SUPERFAMILY SSF88723 12 118 3.64E-21 T 30-10-2018 IPR029060 PIN-like domain superfamily CL1_0530 98f55ad71f3b91987bc18e8a2abef670 125 Pfam PF01850 PIN domain 13 113 1.6E-8 T 30-10-2018 IPR002716 PIN domain CL1_0530 98f55ad71f3b91987bc18e8a2abef670 125 Gene3D G3DSA:3.40.50.1010 9 124 9.0E-25 T 30-10-2018 CL1_0694 81b5a9c3ad9b78c0d1910d482788547b 489 Pfam PF05124 S-layer like family, C-terminal region 384 488 3.4E-10 T 30-10-2018 IPR022651 S-layer protein, C-terminal CL1_0610 b5d0f3bdca653f6e804ba6e69ff30109 126 Hamap MF_00810 50S ribosomal protein L32e [rpl32e]. 2 126 32.047 T 30-10-2018 IPR023654 Ribosomal protein L32e, archaeal GO:0003735|GO:0005840|GO:0006412 CL1_0610 b5d0f3bdca653f6e804ba6e69ff30109 126 SUPERFAMILY SSF52042 5 126 3.27E-47 T 30-10-2018 IPR036351 Ribosomal protein L32e superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0610 b5d0f3bdca653f6e804ba6e69ff30109 126 ProDom PD003823 RIBOSOMAL L32 RIBONUCLEOPROTEIN 60S L32E 50S L32 STRAIN CHROMOSOME DIRECT 19 126 3.0E-55 T 30-10-2018 IPR001515 Ribosomal protein L32e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0610 b5d0f3bdca653f6e804ba6e69ff30109 126 ProSitePatterns PS00580 Ribosomal protein L32e signature. 21 43 - T 30-10-2018 IPR018263 Ribosomal protein L32e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0610 b5d0f3bdca653f6e804ba6e69ff30109 126 Pfam PF01655 Ribosomal protein L32 18 125 2.7E-41 T 30-10-2018 IPR001515 Ribosomal protein L32e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0610 b5d0f3bdca653f6e804ba6e69ff30109 126 SMART SM01393 18 125 1.8E-63 T 30-10-2018 IPR001515 Ribosomal protein L32e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_1167 79b6486b7dff11f8ab46f3d1d487b84e 409 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 219 393 2.6E-11 T 30-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 CL1_1167 79b6486b7dff11f8ab46f3d1d487b84e 409 SUPERFAMILY SSF161098 204 391 4.58E-14 T 30-10-2018 IPR035906 MetI-like superfamily CL1_1167 79b6486b7dff11f8ab46f3d1d487b84e 409 Gene3D G3DSA:1.10.3720.10 197 400 9.0E-11 T 30-10-2018 IPR035906 MetI-like superfamily CL1_0258 8b901b3196f168cfba471d62b1be5152 192 SUPERFAMILY SSF56300 22 157 9.28E-20 T 30-10-2018 CL1_0258 8b901b3196f168cfba471d62b1be5152 192 Gene3D G3DSA:3.60.21.10 14 132 4.7E-9 T 30-10-2018 IPR029052 Metallo-dependent phosphatase-like CL1_0258 8b901b3196f168cfba471d62b1be5152 192 Pfam PF00149 Calcineurin-like phosphoesterase 23 146 3.8E-7 T 30-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CL1_0776 3e23eebfde55b60c8a6a822b6ba96236 189 SUPERFAMILY SSF52317 1 187 8.28E-56 T 30-10-2018 IPR029062 Class I glutamine amidotransferase-like CL1_0776 3e23eebfde55b60c8a6a822b6ba96236 189 Gene3D G3DSA:3.40.50.880 1 187 1.4E-61 T 30-10-2018 IPR029062 Class I glutamine amidotransferase-like CL1_0776 3e23eebfde55b60c8a6a822b6ba96236 189 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 2 186 5.1E-81 T 30-10-2018 IPR004739 GMP synthase, glutamine amidotransferase GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 CL1_0776 3e23eebfde55b60c8a6a822b6ba96236 189 PRINTS PR00096 Glutamine amidotransferase superfamily signature 46 55 9.1E-10 T 30-10-2018 CL1_0776 3e23eebfde55b60c8a6a822b6ba96236 189 PRINTS PR00096 Glutamine amidotransferase superfamily signature 161 174 9.1E-10 T 30-10-2018 CL1_0776 3e23eebfde55b60c8a6a822b6ba96236 189 PRINTS PR00096 Glutamine amidotransferase superfamily signature 73 84 9.1E-10 T 30-10-2018 CL1_0776 3e23eebfde55b60c8a6a822b6ba96236 189 PRINTS PR00097 Anthranilate synthase component II signature 2 16 2.2E-11 T 30-10-2018 CL1_0776 3e23eebfde55b60c8a6a822b6ba96236 189 PRINTS PR00097 Anthranilate synthase component II signature 73 84 2.2E-11 T 30-10-2018 CL1_0776 3e23eebfde55b60c8a6a822b6ba96236 189 PRINTS PR00097 Anthranilate synthase component II signature 46 55 2.2E-11 T 30-10-2018 CL1_0776 3e23eebfde55b60c8a6a822b6ba96236 189 PRINTS PR00097 Anthranilate synthase component II signature 161 174 2.2E-11 T 30-10-2018 CL1_0776 3e23eebfde55b60c8a6a822b6ba96236 189 Hamap MF_01510 GMP synthase [glutamine-hydrolyzing] subunit A [guaAA]. 1 187 45.582 T 30-10-2018 IPR023686 GMP synthase (glutamine-hydrolyzing) subunit A GO:0003922 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 CL1_0776 3e23eebfde55b60c8a6a822b6ba96236 189 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 43 57 9.1E-6 T 30-10-2018 CL1_0776 3e23eebfde55b60c8a6a822b6ba96236 189 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 73 89 9.1E-6 T 30-10-2018 CL1_0776 3e23eebfde55b60c8a6a822b6ba96236 189 Pfam PF00117 Glutamine amidotransferase class-I 4 181 1.5E-44 T 30-10-2018 IPR017926 Glutamine amidotransferase CL1_0260 0653e60e2f4ea561ba763daeda5f0e19 219 Pfam PF03587 EMG1/NEP1 methyltransferase 5 215 1.3E-50 T 30-10-2018 IPR005304 Ribosomal biogenesis, methyltransferase, EMG1/NEP1 GO:0008168 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 CL1_0260 0653e60e2f4ea561ba763daeda5f0e19 219 Gene3D G3DSA:3.40.1280.10 1 218 5.2E-76 T 30-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CL1_0260 0653e60e2f4ea561ba763daeda5f0e19 219 Hamap MF_00554 Ribosomal RNA small subunit methyltransferase Nep1 [nep1]. 2 216 40.618 T 30-10-2018 IPR023503 Ribosome biogenesis methyltransferase NEP1, archaea GO:0008168 CL1_0260 0653e60e2f4ea561ba763daeda5f0e19 219 SUPERFAMILY SSF75217 1 216 1.11E-62 T 30-10-2018 IPR029028 Alpha/beta knot methyltransferases CL1_1139 78befa2e9571d39cd41563c68fdebf54 87 Pfam PF13244 Domain of unknown function (DUF4040) 17 82 3.6E-17 T 30-10-2018 IPR025383 Domain of unknown function DUF4040 CL1_1820 9784df924eec37e6728212b9bb0cc5cb 243 SUPERFAMILY SSF56784 2 205 9.72E-13 T 30-10-2018 IPR036412 HAD-like superfamily CL1_0637 b0fed4c8075600157fda472f31e661bd 460 Pfam PF01637 ATPase domain predominantly from Archaea 6 197 2.9E-17 T 30-10-2018 IPR011579 ATPase domain GO:0005524 CL1_0637 b0fed4c8075600157fda472f31e661bd 460 Pfam PF03008 Archaea bacterial proteins of unknown function 306 405 1.2E-31 T 30-10-2018 IPR004256 Domain of unknown function DUF234, DEXX-box ATPase C-terminal CL1_0637 b0fed4c8075600157fda472f31e661bd 460 Gene3D G3DSA:3.40.50.300 2 163 1.2E-28 T 30-10-2018 CL1_0637 b0fed4c8075600157fda472f31e661bd 460 SUPERFAMILY SSF52540 4 236 1.89E-31 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_0637 b0fed4c8075600157fda472f31e661bd 460 SUPERFAMILY SSF52980 338 397 1.43E-5 T 30-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CL1_0637 b0fed4c8075600157fda472f31e661bd 460 SUPERFAMILY SSF46785 237 315 2.48E-6 T 30-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CL1_2036 2450d9538915f945d44dff5bb1f73c38 397 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 92 110 4.4E-31 T 30-10-2018 IPR006073 GTP binding domain GO:0005525 CL1_2036 2450d9538915f945d44dff5bb1f73c38 397 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 3 23 4.4E-31 T 30-10-2018 IPR006073 GTP binding domain GO:0005525 CL1_2036 2450d9538915f945d44dff5bb1f73c38 397 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 75 90 4.4E-31 T 30-10-2018 IPR006073 GTP binding domain GO:0005525 CL1_2036 2450d9538915f945d44dff5bb1f73c38 397 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 24 42 4.4E-31 T 30-10-2018 IPR006073 GTP binding domain GO:0005525 CL1_2036 2450d9538915f945d44dff5bb1f73c38 397 Pfam PF02824 TGS domain 341 393 3.1E-14 T 30-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 CL1_2036 2450d9538915f945d44dff5bb1f73c38 397 Gene3D G3DSA:1.10.8.470 126 215 4.5E-31 T 30-10-2018 CL1_2036 2450d9538915f945d44dff5bb1f73c38 397 Pfam PF08438 GTPase of unknown function C-terminal 220 327 1.9E-34 T 30-10-2018 IPR013646 Uncharacterised GTP-binding protein, C-terminal CL1_2036 2450d9538915f945d44dff5bb1f73c38 397 Gene3D G3DSA:3.10.20.30 319 397 5.1E-31 T 30-10-2018 IPR012675 Beta-grasp domain superfamily CL1_2036 2450d9538915f945d44dff5bb1f73c38 397 Pfam PF01926 50S ribosome-binding GTPase 2 130 7.5E-20 T 30-10-2018 IPR006073 GTP binding domain GO:0005525 CL1_2036 2450d9538915f945d44dff5bb1f73c38 397 SUPERFAMILY SSF52540 1 315 4.69E-70 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_2036 2450d9538915f945d44dff5bb1f73c38 397 SUPERFAMILY SSF81271 323 393 5.76E-19 T 30-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 CL1_0571 22ca88fb0199d4f5b9b0f8aa83a624f5 278 TIGRFAM TIGR01718 Uridine-psphlse: uridine phosphorylase 18 257 1.1E-95 T 30-10-2018 IPR010058 Uridine phosphorylase GO:0004850|GO:0005737|GO:0009166 KEGG: 00240+2.4.2.3|KEGG: 00983+2.4.2.3|MetaCyc: PWY-5532 CL1_0571 22ca88fb0199d4f5b9b0f8aa83a624f5 278 Pfam PF01048 Phosphorylase superfamily 31 256 5.2E-45 T 30-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CL1_0571 22ca88fb0199d4f5b9b0f8aa83a624f5 278 Gene3D G3DSA:3.40.50.1580 7 261 1.6E-85 T 30-10-2018 CL1_0571 22ca88fb0199d4f5b9b0f8aa83a624f5 278 SUPERFAMILY SSF53167 18 247 6.94E-75 T 30-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 CL1_0571 22ca88fb0199d4f5b9b0f8aa83a624f5 278 ProSitePatterns PS01232 Purine and other phosphorylases family 1 signature. 76 91 - T 30-10-2018 IPR018016 Nucleoside phosphorylase, conserved site GO:0016763 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-73614|Reactome: R-HSA-73621 CL1_0458 d3f77106d8f23fc04d840456fc63827c 65 Gene3D G3DSA:2.20.25.100 11 65 6.4E-25 T 30-10-2018 IPR023407 Ribosomal protein S27e, zinc-binding domain superfamily CL1_0458 d3f77106d8f23fc04d840456fc63827c 65 ProSitePatterns PS01168 Ribosomal protein S27e signature. 19 51 - T 30-10-2018 IPR000592 Ribosomal protein S27e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0458 d3f77106d8f23fc04d840456fc63827c 65 Pfam PF01667 Ribosomal protein S27 11 64 2.3E-26 T 30-10-2018 IPR000592 Ribosomal protein S27e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0458 d3f77106d8f23fc04d840456fc63827c 65 SUPERFAMILY SSF57829 11 65 3.66E-19 T 30-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 CL1_0458 d3f77106d8f23fc04d840456fc63827c 65 Hamap MF_00371 30S ribosomal protein S27e [rps27e]. 5 64 22.447 T 30-10-2018 IPR000592 Ribosomal protein S27e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0460 c99559389b330af66f5910359a975b47 59 Hamap MF_00803 Ribosome biogenesis protein Nop10 [nop10]. 3 53 21.202 T 30-10-2018 IPR023532 H/ACA ribonucleoprotein complex subunit Nop10 , archaeal-type GO:0001522|GO:0030515|GO:0042254 CL1_0460 c99559389b330af66f5910359a975b47 59 SUPERFAMILY SSF144210 4 51 1.1E-21 T 30-10-2018 IPR036756 H/ACA ribonucleoprotein complex, subunit Nop10 superfamily GO:0001522|GO:0030515|GO:0042254 Reactome: R-HSA-6790901 CL1_0460 c99559389b330af66f5910359a975b47 59 Gene3D G3DSA:2.20.28.40 1 59 4.2E-30 T 30-10-2018 IPR036756 H/ACA ribonucleoprotein complex, subunit Nop10 superfamily GO:0001522|GO:0030515|GO:0042254 Reactome: R-HSA-6790901 CL1_0460 c99559389b330af66f5910359a975b47 59 Pfam PF04135 Nucleolar RNA-binding protein, Nop10p family 1 51 4.9E-27 T 30-10-2018 IPR007264 H/ACA ribonucleoprotein complex, subunit Nop10 GO:0001522|GO:0030515|GO:0042254 Reactome: R-HSA-6790901 CL1_1486 c03a6738c4c25ffa5e533b100b0b30fe 67 Pfam PF00808 Histone-like transcription factor (CBF/NF-Y) and archaeal histone 2 65 3.2E-21 T 30-10-2018 IPR003958 Transcription factor CBF/NF-Y/archaeal histone domain CL1_1486 c03a6738c4c25ffa5e533b100b0b30fe 67 SUPERFAMILY SSF47113 3 66 3.33E-20 T 30-10-2018 IPR009072 Histone-fold GO:0046982 CL1_1486 c03a6738c4c25ffa5e533b100b0b30fe 67 SMART SM00803 12 66 0.0023 T 30-10-2018 IPR004823 TATA box binding protein associated factor (TAF) GO:0006352 CL1_1486 c03a6738c4c25ffa5e533b100b0b30fe 67 Gene3D G3DSA:1.10.20.10 1 67 9.3E-23 T 30-10-2018 IPR009072 Histone-fold GO:0046982 CL1_2014 e1536aa6e33c16913b1d635709f5eca5 478 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 1 224 8.7E-21 T 30-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain CL1_2014 e1536aa6e33c16913b1d635709f5eca5 478 SUPERFAMILY SSF52540 1 231 9.46E-45 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_2014 e1536aa6e33c16913b1d635709f5eca5 478 Gene3D G3DSA:3.40.50.880 242 395 3.0E-16 T 30-10-2018 IPR029062 Class I glutamine amidotransferase-like CL1_2014 e1536aa6e33c16913b1d635709f5eca5 478 Hamap MF_00028 Cobyric acid synthase [cobQ]. 1 478 157.918 T 30-10-2018 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 CL1_2014 e1536aa6e33c16913b1d635709f5eca5 478 TIGRFAM TIGR00313 cobQ: cobyric acid synthase CobQ 1 471 8.5E-156 T 30-10-2018 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 CL1_2014 e1536aa6e33c16913b1d635709f5eca5 478 Gene3D G3DSA:3.40.50.300 1 236 8.8E-46 T 30-10-2018 CL1_2014 e1536aa6e33c16913b1d635709f5eca5 478 SUPERFAMILY SSF52317 187 363 1.05E-28 T 30-10-2018 IPR029062 Class I glutamine amidotransferase-like CL1_2014 e1536aa6e33c16913b1d635709f5eca5 478 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 245 427 1.1E-50 T 30-10-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 CL1_1835 de28e10694f48977dcb090a89d72a660 175 Gene3D G3DSA:3.30.1990.20 145 174 7.8E-9 T 30-10-2018 CL1_1835 de28e10694f48977dcb090a89d72a660 175 SUPERFAMILY SSF55729 15 169 2.16E-26 T 30-10-2018 IPR016181 Acyl-CoA N-acyltransferase CL1_1835 de28e10694f48977dcb090a89d72a660 175 Pfam PF00583 Acetyltransferase (GNAT) family 34 160 3.7E-16 T 30-10-2018 IPR000182 GNAT domain CL1_1835 de28e10694f48977dcb090a89d72a660 175 Gene3D G3DSA:3.40.630.30 1 144 3.7E-61 T 30-10-2018 CL1_1186 7d17d63dc06d92036fe82609dff276c9 192 SUPERFAMILY SSF57903 151 187 8.63E-6 T 30-10-2018 IPR011011 Zinc finger, FYVE/PHD-type CL1_0836 d9b14accd21e97163899a6a3eece04a5 375 Gene3D G3DSA:3.40.50.2000 193 356 5.3E-35 T 30-10-2018 CL1_0836 d9b14accd21e97163899a6a3eece04a5 375 Gene3D G3DSA:3.40.50.2000 12 192 5.2E-8 T 30-10-2018 CL1_0836 d9b14accd21e97163899a6a3eece04a5 375 SUPERFAMILY SSF53756 44 338 9.73E-6 T 30-10-2018 CL1_1575 ada00ccc68c1bbc0d2e05878bb641c52 77 SUPERFAMILY SSF160374 1 73 2.75E-23 T 30-10-2018 CL1_1575 ada00ccc68c1bbc0d2e05878bb641c52 77 Gene3D G3DSA:3.10.20.10 3 76 2.5E-25 T 30-10-2018 CL1_1575 ada00ccc68c1bbc0d2e05878bb641c52 77 Hamap MF_00273 50S ribosomal protein L18Ae [rpl18a]. 3 58 18.498 T 30-10-2018 IPR028877 50S ribosomal protein L18Ae/60S ribosomal protein L20 and L18a Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_1575 ada00ccc68c1bbc0d2e05878bb641c52 77 ProDom PD010302 RIBOSOMAL LX 50S RIBONUCLEOPROTEIN HL32 DIRECT SEQUENCING LXA LSU 6 57 5.0E-16 T 30-10-2018 IPR002768 50S ribosomal protein L18Ae, archaea GO:0003735|GO:0005840|GO:0006412 CL1_1575 ada00ccc68c1bbc0d2e05878bb641c52 77 Pfam PF01775 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A 2 58 1.1E-10 T 30-10-2018 IPR023573 Ribosomal protein 50S-L18Ae/60S-L20/60S-L18A GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0204 0896d94b2b2584be36e84f0264e34dfd 433 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 23 430 3.4E-97 T 30-10-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 CL1_0204 0896d94b2b2584be36e84f0264e34dfd 433 Pfam PF00860 Permease family 24 401 5.0E-95 T 30-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 CL1_0204 0896d94b2b2584be36e84f0264e34dfd 433 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 348 368 - T 30-10-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 CL1_1332 60f20f6bbbc3d3cfacd713f47c810f9d 304 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 8 51 3.5E-8 T 30-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 CL1_1332 60f20f6bbbc3d3cfacd713f47c810f9d 304 Gene3D G3DSA:1.20.58.220 134 236 4.6E-12 T 30-10-2018 IPR038078 PhoU-like domain superfamily CL1_1332 60f20f6bbbc3d3cfacd713f47c810f9d 304 SMART SM00966 8 54 1.8E-9 T 30-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 CL1_1332 60f20f6bbbc3d3cfacd713f47c810f9d 304 Pfam PF01895 PhoU domain 138 230 1.7E-14 T 30-10-2018 IPR026022 PhoU domain CL1_1332 60f20f6bbbc3d3cfacd713f47c810f9d 304 SUPERFAMILY SSF109755 125 301 1.44E-18 T 30-10-2018 CL1_1496 94f8b0d13fb670841743372410825aff 141 Gene3D G3DSA:2.60.120.630 1 141 3.9E-52 T 30-10-2018 IPR023131 Mth639-like domain superfamily CL1_1496 94f8b0d13fb670841743372410825aff 141 Pfam PF04027 Domain of unknown function (DUF371) 6 136 2.4E-49 T 30-10-2018 IPR007171 Protein of unknown function DUF371 CL1_1246 d8b5b19d291e6eb3e8e91e05b1a6cf9e 311 Gene3D G3DSA:3.40.50.970 101 310 1.4E-69 T 30-10-2018 CL1_1246 d8b5b19d291e6eb3e8e91e05b1a6cf9e 311 Gene3D G3DSA:3.40.50.970 9 100 2.6E-5 T 30-10-2018 CL1_1246 d8b5b19d291e6eb3e8e91e05b1a6cf9e 311 SUPERFAMILY SSF52518 16 309 1.37E-73 T 30-10-2018 IPR029061 Thiamin diphosphate-binding fold CL1_1246 d8b5b19d291e6eb3e8e91e05b1a6cf9e 311 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 63 218 8.1E-20 T 30-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CL1_0973 6bd0c27f6bd94c0d630316d9aa8acab9 1128 SUPERFAMILY SSF49344 16 213 3.14E-12 T 30-10-2018 CL1_0973 6bd0c27f6bd94c0d630316d9aa8acab9 1128 Pfam PF07705 CARDB 436 532 1.7E-19 T 30-10-2018 IPR011635 CARDB domain CL1_0973 6bd0c27f6bd94c0d630316d9aa8acab9 1128 Gene3D G3DSA:2.60.40.1190 15 222 1.4E-6 T 30-10-2018 CL1_0973 6bd0c27f6bd94c0d630316d9aa8acab9 1128 Gene3D G3DSA:2.60.40.1190 225 423 1.1E-6 T 30-10-2018 CL1_0973 6bd0c27f6bd94c0d630316d9aa8acab9 1128 Gene3D G3DSA:2.60.40.10 424 540 3.2E-32 T 30-10-2018 IPR013783 Immunoglobulin-like fold CL1_0973 6bd0c27f6bd94c0d630316d9aa8acab9 1128 SUPERFAMILY SSF49344 224 419 4.51E-12 T 30-10-2018 CL1_0973 6bd0c27f6bd94c0d630316d9aa8acab9 1128 SUPERFAMILY SSF49344 921 1085 5.1E-11 T 30-10-2018 CL1_0693 5d35aaa6069032702af7a82fc46ee41f 377 Gene3D G3DSA:1.20.1250.20 192 370 4.5E-20 T 30-10-2018 CL1_0693 5d35aaa6069032702af7a82fc46ee41f 377 Gene3D G3DSA:1.20.1250.20 1 188 2.0E-23 T 30-10-2018 CL1_0693 5d35aaa6069032702af7a82fc46ee41f 377 Pfam PF07690 Major Facilitator Superfamily 6 170 5.4E-20 T 30-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CL1_0693 5d35aaa6069032702af7a82fc46ee41f 377 Pfam PF07690 Major Facilitator Superfamily 200 367 8.7E-15 T 30-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CL1_0693 5d35aaa6069032702af7a82fc46ee41f 377 SUPERFAMILY SSF103473 2 368 4.19E-52 T 30-10-2018 IPR036259 MFS transporter superfamily CL1_0011 c0fea8735de3fe15a87a301166d0104a 283 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 56 204 1.8E-39 T 30-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CL1_0011 c0fea8735de3fe15a87a301166d0104a 283 SUPERFAMILY SSF52518 18 272 1.38E-75 T 30-10-2018 IPR029061 Thiamin diphosphate-binding fold CL1_0011 c0fea8735de3fe15a87a301166d0104a 283 Gene3D G3DSA:3.40.50.970 67 269 7.1E-33 T 30-10-2018 CL1_1460 4762323731dea4d93cf57020c8bbcef9 122 Pfam PF09946 Predicted membrane protein (DUF2178) 14 112 3.2E-8 T 30-10-2018 IPR019235 Protein of unknown function DUF2178, transmembrane CL1_0070 c9327e7e089d0cd26542ceafc48aef73 99 Gene3D G3DSA:3.30.460.10 2 98 1.4E-25 T 30-10-2018 CL1_0070 c9327e7e089d0cd26542ceafc48aef73 99 Pfam PF01909 Nucleotidyltransferase domain 16 98 1.2E-17 T 30-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 CL1_0070 c9327e7e089d0cd26542ceafc48aef73 99 SUPERFAMILY SSF81301 2 99 1.43E-27 T 30-10-2018 CL1_0216 000992f4d2f7e0b57527d29502009ad2 155 Pfam PF01161 Phosphatidylethanolamine-binding protein 15 152 1.6E-35 T 30-10-2018 IPR008914 Phosphatidylethanolamine-binding protein CL1_0216 000992f4d2f7e0b57527d29502009ad2 155 SUPERFAMILY SSF49777 7 154 2.35E-46 T 30-10-2018 IPR036610 PEBP-like superfamily CL1_0216 000992f4d2f7e0b57527d29502009ad2 155 Gene3D G3DSA:3.90.280.10 5 155 2.1E-51 T 30-10-2018 IPR036610 PEBP-like superfamily CL1_0216 000992f4d2f7e0b57527d29502009ad2 155 TIGRFAM TIGR00481 TIGR00481: Raf kinase inhibitor-like protein, YbhB/YbcL family 20 152 5.6E-44 T 30-10-2018 IPR005247 YbhB/YbcL CL1_0991 823711e4c504f1e52f76eda728f814b6 445 SUPERFAMILY SSF53649 3 313 3.34E-37 T 30-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 CL1_0991 823711e4c504f1e52f76eda728f814b6 445 Pfam PF00884 Sulfatase 4 329 1.9E-23 T 30-10-2018 IPR000917 Sulfatase, N-terminal GO:0008484 CL1_0369 0b037a76506949e0b547d0188cb8fed5 264 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 10 77 1.7E-18 T 30-10-2018 IPR002831 Transcription regulator TrmB, N-terminal CL1_0369 0b037a76506949e0b547d0188cb8fed5 264 Pfam PF11495 Archaeal transcriptional regulator TrmB 126 262 3.1E-5 T 30-10-2018 IPR021586 Transcription regulator TrmB, C-terminal CL1_0369 0b037a76506949e0b547d0188cb8fed5 264 SUPERFAMILY SSF46785 10 96 6.96E-7 T 30-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CL1_0369 0b037a76506949e0b547d0188cb8fed5 264 Gene3D G3DSA:3.30.870.10 122 264 3.3E-78 T 30-10-2018 CL1_0369 0b037a76506949e0b547d0188cb8fed5 264 Gene3D G3DSA:1.10.10.10 1 75 3.2E-21 T 30-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CL1_1323 57c4daea85931f77b4a291aea9760e9e 235 Pfam PF07758 Protein of unknown function (DUF1614) 57 234 4.0E-58 T 30-10-2018 IPR011672 Protein of unknown function DUF1614 CL1_0911 27356226784b5b1ac56ce83b1335c6b5 254 Gene3D G3DSA:3.40.50.620 6 254 5.3E-94 T 30-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CL1_0911 27356226784b5b1ac56ce83b1335c6b5 254 Hamap MF_00193 NH(3)-dependent NAD(+) synthetase [nadE]. 5 252 52.244 T 30-10-2018 IPR022926 NH(3)-dependent NAD(+) synthetase GO:0008795|GO:0009435 KEGG: 00760+6.3.1.5 CL1_0911 27356226784b5b1ac56ce83b1335c6b5 254 TIGRFAM TIGR00552 nadE: NAD+ synthetase 9 249 6.0E-83 T 30-10-2018 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 CL1_0911 27356226784b5b1ac56ce83b1335c6b5 254 SUPERFAMILY SSF52402 3 249 7.72E-79 T 30-10-2018 CL1_0911 27356226784b5b1ac56ce83b1335c6b5 254 Pfam PF02540 NAD synthase 10 249 5.7E-88 T 30-10-2018 IPR022310 NAD/GMP synthase CL1_1681 5b3c3af4169469f6db7c763c1f3e4ea2 711 SUPERFAMILY SSF52980 20 130 5.9E-7 T 30-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CL1_1681 5b3c3af4169469f6db7c763c1f3e4ea2 711 Pfam PF04471 Restriction endonuclease 15 124 1.0E-12 T 30-10-2018 IPR007560 Restriction endonuclease type IV, Mrr GO:0003677|GO:0004519|GO:0009307 CL1_1097 aaa6b60f911a7a3f2713939ad00f8722 172 SUPERFAMILY SSF46785 4 137 1.33E-20 T 30-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CL1_1097 aaa6b60f911a7a3f2713939ad00f8722 172 PIRSF PIRSF006707 1 172 2.8E-36 T 30-10-2018 IPR026282 DNA-binding protein, MJ1563 type CL1_1097 aaa6b60f911a7a3f2713939ad00f8722 172 Pfam PF12802 MarR family 35 81 6.3E-9 T 30-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CL1_1097 aaa6b60f911a7a3f2713939ad00f8722 172 Gene3D G3DSA:1.10.10.10 2 86 8.8E-23 T 30-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CL1_1444 35a6b7756145f865801a217f3e1c0011 115 SUPERFAMILY SSF69695 2 108 8.76E-22 T 30-10-2018 IPR036521 Signal recognition particle, subunit SRP19-like superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 CL1_1444 35a6b7756145f865801a217f3e1c0011 115 Pfam PF01922 SRP19 protein 5 86 2.1E-13 T 30-10-2018 IPR002778 Signal recognition particle, SRP19 subunit GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 CL1_1444 35a6b7756145f865801a217f3e1c0011 115 Gene3D G3DSA:3.30.56.30 1 106 9.3E-30 T 30-10-2018 IPR036521 Signal recognition particle, subunit SRP19-like superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 CL1_1395 e1658d5e9dc8f857f730465fdae1c60d 280 Gene3D G3DSA:3.80.30.30 51 252 4.2E-13 T 30-10-2018 CL1_1395 e1658d5e9dc8f857f730465fdae1c60d 280 Pfam PF04055 Radical SAM superfamily 23 187 5.9E-16 T 30-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CL1_1395 e1658d5e9dc8f857f730465fdae1c60d 280 SUPERFAMILY SSF102114 9 217 2.62E-16 T 30-10-2018 CL1_1395 e1658d5e9dc8f857f730465fdae1c60d 280 SMART SM00729 18 228 8.4E-13 T 30-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 CL1_1165 62c7a15b8e354d376d8fa2e1f8cdafa3 306 Pfam PF12679 ABC-2 family transporter protein 5 305 7.1E-48 T 30-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 CL1_0539 c138f5587753919c86b5556b661c1a5e 203 ProSitePatterns PS00854 Proteasome beta-type subunits signature. 11 58 - T 30-10-2018 IPR016050 Proteasome beta-type subunit, conserved site GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 CL1_0539 c138f5587753919c86b5556b661c1a5e 203 Gene3D G3DSA:3.60.20.10 3 203 2.7E-69 T 30-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CL1_0539 c138f5587753919c86b5556b661c1a5e 203 TIGRFAM TIGR03634 arc_protsome_B: proteasome endopeptidase complex, archaeal, beta subunit 7 190 8.4E-77 T 30-10-2018 IPR019983 Peptidase T1A, proteasome beta-subunit, archaeal GO:0004175|GO:0005839|GO:0051603 CL1_0539 c138f5587753919c86b5556b661c1a5e 203 Pfam PF00227 Proteasome subunit 6 185 9.2E-54 T 30-10-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 CL1_0539 c138f5587753919c86b5556b661c1a5e 203 SUPERFAMILY SSF56235 5 202 2.44E-65 T 30-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CL1_0539 c138f5587753919c86b5556b661c1a5e 203 Hamap MF_02113_A Proteasome subunit beta [prcB]. 3 197 34.741 T 30-10-2018 IPR019983 Peptidase T1A, proteasome beta-subunit, archaeal GO:0004175|GO:0005839|GO:0051603 CL1_0539 c138f5587753919c86b5556b661c1a5e 203 PRINTS PR00141 Proteasome component signature 15 30 4.0E-10 T 30-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 CL1_0539 c138f5587753919c86b5556b661c1a5e 203 PRINTS PR00141 Proteasome component signature 171 182 4.0E-10 T 30-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 CL1_0539 c138f5587753919c86b5556b661c1a5e 203 PRINTS PR00141 Proteasome component signature 146 157 4.0E-10 T 30-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 CL1_0539 c138f5587753919c86b5556b661c1a5e 203 PRINTS PR00141 Proteasome component signature 135 146 4.0E-10 T 30-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 CL1_1192 1e902b44db4a66f6a67e2d9bce5dfa5c 588 Pfam PF13353 4Fe-4S single cluster domain 142 225 7.8E-7 T 30-10-2018 CL1_1192 1e902b44db4a66f6a67e2d9bce5dfa5c 588 SUPERFAMILY SSF102114 127 395 8.89E-46 T 30-10-2018 CL1_1192 1e902b44db4a66f6a67e2d9bce5dfa5c 588 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 144 155 - T 30-10-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CL1_1192 1e902b44db4a66f6a67e2d9bce5dfa5c 588 Gene3D G3DSA:3.20.20.70 128 401 2.0E-34 T 30-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CL1_1192 1e902b44db4a66f6a67e2d9bce5dfa5c 588 Pfam PF04055 Radical SAM superfamily 142 301 1.6E-21 T 30-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CL1_0306 d504ac67dced925020d603a3212447ca 242 Gene3D G3DSA:3.40.50.300 10 238 6.6E-63 T 30-10-2018 CL1_1802 06a1dcf80a4969aaa7518afc5dbd2186 330 Gene3D G3DSA:3.40.50.300 5 329 1.6E-85 T 30-10-2018 CL1_1802 06a1dcf80a4969aaa7518afc5dbd2186 330 Pfam PF02374 Anion-transporting ATPase 12 328 3.6E-70 T 30-10-2018 IPR025723 Anion-transporting ATPase-like domain Reactome: R-HSA-381038 CL1_1802 06a1dcf80a4969aaa7518afc5dbd2186 330 SUPERFAMILY SSF52540 9 322 1.12E-42 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_1802 06a1dcf80a4969aaa7518afc5dbd2186 330 TIGRFAM TIGR00345 GET3_arsA_TRC40: transport-energizing ATPase, TRC40/GET3/ArsA family 15 323 2.3E-71 T 30-10-2018 IPR016300 Arsenical pump ATPase, ArsA/GET3 GO:0005524|GO:0016887 Reactome: R-HSA-381038 CL1_1853 09e625aec44f8dc3d87d9857f5ff0e1a 205 Pfam PF00583 Acetyltransferase (GNAT) family 38 177 8.0E-19 T 30-10-2018 IPR000182 GNAT domain CL1_1853 09e625aec44f8dc3d87d9857f5ff0e1a 205 SUPERFAMILY SSF55729 12 201 8.06E-27 T 30-10-2018 IPR016181 Acyl-CoA N-acyltransferase CL1_1853 09e625aec44f8dc3d87d9857f5ff0e1a 205 Gene3D G3DSA:3.40.630.30 8 205 1.6E-38 T 30-10-2018 CL1_0746 226c02c1262e213d27f9fea7158803ba 113 Gene3D G3DSA:1.10.10.10 1 109 2.9E-35 T 30-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CL1_0746 226c02c1262e213d27f9fea7158803ba 113 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 12 83 1.9E-9 T 30-10-2018 IPR002831 Transcription regulator TrmB, N-terminal CL1_0746 226c02c1262e213d27f9fea7158803ba 113 SUPERFAMILY SSF46785 3 105 6.03E-16 T 30-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CL1_0531 8ebc7904f5f85170c7c0a0b322cd3a70 393 Pfam PF07282 Putative transposase DNA-binding domain 290 356 3.4E-25 T 30-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal CL1_0531 8ebc7904f5f85170c7c0a0b322cd3a70 393 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 238 317 5.0E-26 T 30-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal CL1_0531 8ebc7904f5f85170c7c0a0b322cd3a70 393 SUPERFAMILY SSF75712 274 337 4.45E-10 T 30-10-2018 CL1_0531 8ebc7904f5f85170c7c0a0b322cd3a70 393 Pfam PF01385 Probable transposase 169 259 1.3E-6 T 30-10-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 CL1_1372 b8163569ae8fc40fd417d81156701912 225 Pfam PF00696 Amino acid kinase family 1 202 2.8E-34 T 30-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 CL1_1372 b8163569ae8fc40fd417d81156701912 225 SUPERFAMILY SSF53633 1 224 3.67E-51 T 30-10-2018 IPR036393 Acetylglutamate kinase-like superfamily CL1_1372 b8163569ae8fc40fd417d81156701912 225 PIRSF PIRSF005650 1 225 4.8E-60 T 30-10-2018 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 CL1_1372 b8163569ae8fc40fd417d81156701912 225 Gene3D G3DSA:3.40.1160.10 1 225 2.7E-60 T 30-10-2018 IPR036393 Acetylglutamate kinase-like superfamily CL1_1372 b8163569ae8fc40fd417d81156701912 225 TIGRFAM TIGR02076 pyrH_arch: putative uridylate kinase 3 224 4.3E-86 T 30-10-2018 IPR011818 Uridylate kinase, archaeal/spirochete, putative GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 CL1_1372 b8163569ae8fc40fd417d81156701912 225 Hamap MF_01220_A Uridylate kinase [pyrH]. 1 225 34.996 T 30-10-2018 IPR011818 Uridylate kinase, archaeal/spirochete, putative GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 CL1_0191 2a60b01f4ee4635a72580c7d12e9c573 84 Pfam PF04066 Multiple resistance and pH regulation protein F (MrpF / PhaF) 30 81 5.8E-18 T 30-10-2018 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 CL1_1973 cf12d779da5961c2f916f6c6ef807386 86 Pfam PF01402 Ribbon-helix-helix protein, copG family 6 41 2.4E-6 T 30-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 CL1_1668 4adf9cb029a4cf763db85b2eb2ee8429 250 Pfam PF01261 Xylose isomerase-like TIM barrel 16 215 2.3E-37 T 30-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CL1_1668 4adf9cb029a4cf763db85b2eb2ee8429 250 SUPERFAMILY SSF51658 10 246 3.4E-49 T 30-10-2018 IPR036237 Xylose isomerase-like superfamily CL1_1668 4adf9cb029a4cf763db85b2eb2ee8429 250 Gene3D G3DSA:3.20.20.150 2 250 4.9E-61 T 30-10-2018 CL1_1997 989e6f48e0e975037712923aa121c6f2 210 Gene3D G3DSA:3.40.50.850 13 206 1.6E-45 T 30-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 CL1_1997 989e6f48e0e975037712923aa121c6f2 210 SUPERFAMILY SSF52499 17 207 1.14E-47 T 30-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 CL1_1997 989e6f48e0e975037712923aa121c6f2 210 Pfam PF00857 Isochorismatase family 34 196 2.5E-37 T 30-10-2018 IPR000868 Isochorismatase-like GO:0003824 CL1_0214 a662b777c59eb0db0b652c75ed6c12e5 154 Gene3D G3DSA:1.25.40.10 2 50 2.4E-7 T 30-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 CL1_0214 a662b777c59eb0db0b652c75ed6c12e5 154 Gene3D G3DSA:1.25.40.10 51 153 4.3E-19 T 30-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 CL1_0214 a662b777c59eb0db0b652c75ed6c12e5 154 SUPERFAMILY SSF48452 8 136 2.04E-6 T 30-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 CL1_1214 1f868575aced4b1a92c7af023a0fcc2b 466 Pfam PF09852 Predicted membrane protein (DUF2079) 37 448 1.4E-55 T 30-10-2018 IPR018650 Sulfolobus virus STSV1, Orf64 CL1_0657 d89abd0e0773a49ca125203b479dcd5a 401 TIGRFAM TIGR01109 Na_pump_decarbB: sodium ion-translocating decarboxylase, beta subunit 23 395 6.3E-159 T 30-10-2018 IPR005661 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit GO:0006814|GO:0016829 KEGG: 00620+4.1.1.3 CL1_0657 d89abd0e0773a49ca125203b479dcd5a 401 PIRSF PIRSF015658 1 401 2.3E-168 T 30-10-2018 IPR005661 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit GO:0006814|GO:0016829 KEGG: 00620+4.1.1.3 CL1_0657 d89abd0e0773a49ca125203b479dcd5a 401 Pfam PF03977 Na+-transporting oxaloacetate decarboxylase beta subunit 24 399 2.9E-159 T 30-10-2018 IPR005661 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit GO:0006814|GO:0016829 KEGG: 00620+4.1.1.3 CL1_1938 a16324656605ea8b3a10fd27b6afe9c0 291 Gene3D G3DSA:3.60.15.10 1 220 4.2E-28 T 30-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like CL1_1938 a16324656605ea8b3a10fd27b6afe9c0 291 SMART SM00849 15 200 1.5E-15 T 30-10-2018 IPR001279 Metallo-beta-lactamase CL1_1938 a16324656605ea8b3a10fd27b6afe9c0 291 SUPERFAMILY SSF56281 4 274 5.55E-37 T 30-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like CL1_1938 a16324656605ea8b3a10fd27b6afe9c0 291 Pfam PF00753 Metallo-beta-lactamase superfamily 17 190 2.9E-11 T 30-10-2018 IPR001279 Metallo-beta-lactamase CL1_1269 9a9193ff465d8474a55fec9f2b5a4840 149 SUPERFAMILY SSF52402 2 149 1.34E-26 T 30-10-2018 CL1_1269 9a9193ff465d8474a55fec9f2b5a4840 149 Gene3D G3DSA:3.40.50.620 1 149 5.8E-31 T 30-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CL1_1269 9a9193ff465d8474a55fec9f2b5a4840 149 Pfam PF00582 Universal stress protein family 2 149 5.5E-23 T 30-10-2018 IPR006016 UspA CL1_0160 8305f96d442db10cf73644803146947a 200 Hamap MF_00359 30S ribosomal protein S3Ae [rps3ae]. 8 198 36.629 T 30-10-2018 IPR030838 30S ribosomal protein S3Ae GO:0003735|GO:0005840|GO:0006412 CL1_0160 8305f96d442db10cf73644803146947a 200 ProSitePatterns PS01191 Ribosomal protein S3Ae signature. 47 59 - T 30-10-2018 IPR018281 Ribosomal protein S3Ae, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0160 8305f96d442db10cf73644803146947a 200 Pfam PF01015 Ribosomal S3Ae family 9 198 1.3E-66 T 30-10-2018 IPR001593 Ribosomal protein S3Ae GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0160 8305f96d442db10cf73644803146947a 200 SMART SM01397 8 198 1.3E-100 T 30-10-2018 IPR001593 Ribosomal protein S3Ae GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0132 5fba26c27ab373d7e502d7dbc06760dc 487 Gene3D G3DSA:3.90.1640.10 164 366 2.4E-27 T 30-10-2018 CL1_0132 5fba26c27ab373d7e502d7dbc06760dc 487 Pfam PF01368 DHH family 165 315 4.2E-10 T 30-10-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CL1_0132 5fba26c27ab373d7e502d7dbc06760dc 487 Pfam PF02272 DHHA1 domain 355 470 1.9E-13 T 30-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 CL1_0132 5fba26c27ab373d7e502d7dbc06760dc 487 SUPERFAMILY SSF64182 162 453 3.01E-57 T 30-10-2018 IPR038763 DHH phosphoesterase superfamily CL1_0132 5fba26c27ab373d7e502d7dbc06760dc 487 Gene3D G3DSA:3.40.50.720 1 140 3.3E-21 T 30-10-2018 CL1_0132 5fba26c27ab373d7e502d7dbc06760dc 487 SUPERFAMILY SSF51735 1 138 1.14E-19 T 30-10-2018 IPR036291 NAD(P)-binding domain superfamily CL1_0132 5fba26c27ab373d7e502d7dbc06760dc 487 Pfam PF02254 TrkA-N domain 3 96 2.4E-19 T 30-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 CL1_1330 6f1250842ddf20660b363672a11dcba4 194 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 11 190 1.7E-34 T 30-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 CL1_1330 6f1250842ddf20660b363672a11dcba4 194 SUPERFAMILY SSF53323 2 193 3.01E-27 T 30-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 CL1_1330 6f1250842ddf20660b363672a11dcba4 194 Gene3D G3DSA:3.40.920.10 1 194 3.6E-34 T 30-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 CL1_0100 8d37142c74d7a18cc3b31ab5fa90f7e0 222 Gene3D G3DSA:1.10.150.520 15 84 1.7E-8 T 30-10-2018 CL1_0100 8d37142c74d7a18cc3b31ab5fa90f7e0 222 SUPERFAMILY SSF56784 4 187 4.27E-14 T 30-10-2018 IPR036412 HAD-like superfamily CL1_0100 8d37142c74d7a18cc3b31ab5fa90f7e0 222 Gene3D G3DSA:3.40.50.1000 5 133 1.7E-8 T 30-10-2018 IPR023214 HAD superfamily CL1_0995 e1d6acd224fdb5400a51b13378e568d4 314 Gene3D G3DSA:3.90.550.10 4 215 1.4E-24 T 30-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases CL1_0995 e1d6acd224fdb5400a51b13378e568d4 314 SUPERFAMILY SSF53448 13 228 3.75E-31 T 30-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases CL1_0995 e1d6acd224fdb5400a51b13378e568d4 314 Pfam PF00535 Glycosyl transferase family 2 14 152 2.7E-13 T 30-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CL1_1919 047126d41b0d07f65c4a9b3be5b2ce9e 138 Gene3D G3DSA:1.10.10.60 85 129 7.6E-8 T 30-10-2018 CL1_1919 047126d41b0d07f65c4a9b3be5b2ce9e 138 SUPERFAMILY SSF46689 85 126 2.46E-7 T 30-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 CL1_1919 047126d41b0d07f65c4a9b3be5b2ce9e 138 Pfam PF02796 Helix-turn-helix domain of resolvase 85 123 2.7E-6 T 30-10-2018 IPR006120 Resolvase, HTH domain GO:0000150|GO:0003677|GO:0006310 CL1_0988 77b134f387053867ae4b64bbb3a2aafa 178 Hamap MF_00065 Adenylyl-sulfate kinase [cysC]. 5 175 37.278 T 30-10-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 CL1_0988 77b134f387053867ae4b64bbb3a2aafa 178 SUPERFAMILY SSF52540 3 174 7.32E-37 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_0988 77b134f387053867ae4b64bbb3a2aafa 178 TIGRFAM TIGR00455 apsK: adenylyl-sulfate kinase 3 170 5.8E-69 T 30-10-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 CL1_0988 77b134f387053867ae4b64bbb3a2aafa 178 Gene3D G3DSA:3.40.50.300 2 178 2.2E-60 T 30-10-2018 CL1_0988 77b134f387053867ae4b64bbb3a2aafa 178 Pfam PF01583 Adenylylsulphate kinase 6 157 9.6E-61 T 30-10-2018 CL1_0004 5d4af305e7a7f255de4137d1fa606b50 129 Gene3D G3DSA:2.60.120.1140 5 96 3.2E-10 T 30-10-2018 IPR038695 Saro_0823-like superfamily CL1_0004 5d4af305e7a7f255de4137d1fa606b50 129 Pfam PF02643 Uncharacterized ACR, COG1430 7 86 5.0E-13 T 30-10-2018 IPR003795 Protein of unknown function DUF192 CL1_0111 8f4aa4b0fad6104d22293a56af11e949 278 Gene3D G3DSA:1.10.10.10 190 272 9.8E-10 T 30-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CL1_0111 8f4aa4b0fad6104d22293a56af11e949 278 SUPERFAMILY SSF46785 202 270 2.14E-11 T 30-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CL1_0111 8f4aa4b0fad6104d22293a56af11e949 278 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 211 270 6.3E-9 T 30-10-2018 IPR002831 Transcription regulator TrmB, N-terminal CL1_1319 587055bb17de99dc8d049e9158af803f 471 SMART SM00316 92 152 2.9E-4 T 30-10-2018 IPR022967 RNA-binding domain, S1 CL1_1319 587055bb17de99dc8d049e9158af803f 471 Pfam PF04167 Protein of unknown function (DUF402) 379 442 1.4E-13 T 30-10-2018 IPR007295 Domain of unknown function DUF402 CL1_1319 587055bb17de99dc8d049e9158af803f 471 Hamap MF_01910 RNA-binding protein AU-1 [aubA]. 7 471 34.208 T 30-10-2018 IPR016730 RNA-binding AU-1 GO:0003723 CL1_1319 587055bb17de99dc8d049e9158af803f 471 PIRSF PIRSF018644 5 471 4.6E-192 T 30-10-2018 IPR016730 RNA-binding AU-1 GO:0003723 CL1_1319 587055bb17de99dc8d049e9158af803f 471 Pfam PF10150 Ribonuclease E/G family 152 262 2.9E-11 T 30-10-2018 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 CL1_1319 587055bb17de99dc8d049e9158af803f 471 SUPERFAMILY SSF159234 319 471 4.84E-31 T 30-10-2018 IPR035930 FomD-like superfamily CL1_1319 587055bb17de99dc8d049e9158af803f 471 Gene3D G3DSA:2.40.380.10 366 471 1.2E-10 T 30-10-2018 IPR035930 FomD-like superfamily CL1_0685 63dbbeadf61efa9eee1cffea1304f19c 132 Pfam PF09999 Uncharacterized protein conserved in archaea (DUF2240) 8 64 5.5E-6 T 30-10-2018 IPR018716 Protein of unknown function DUF2240 CL1_1382 75bf58db5afdb7c4f973f2d21dd6ad82 538 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 33 435 5.6E-76 T 30-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 CL1_1382 75bf58db5afdb7c4f973f2d21dd6ad82 538 Gene3D G3DSA:1.20.1730.10 22 508 5.1E-88 T 30-10-2018 IPR038377 Sodium/glucose symporter superfamily CL1_1382 75bf58db5afdb7c4f973f2d21dd6ad82 538 Pfam PF00474 Sodium:solute symporter family 33 435 8.3E-82 T 30-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 CL1_0964 71bce05f7391ccb915a883ba49b1b30f 204 Pfam PF01914 MarC family integral membrane protein 6 196 2.5E-30 T 30-10-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 CL1_0801 77563a0caf4b698c0ef610ed52bf4db4 463 Gene3D G3DSA:2.60.120.200 292 404 1.6E-5 T 30-10-2018 CL1_0801 77563a0caf4b698c0ef610ed52bf4db4 463 Pfam PF12138 Spherulation-specific family 4 32 243 2.9E-34 T 30-10-2018 IPR021986 Spherulation-specific family 4 CL1_0801 77563a0caf4b698c0ef610ed52bf4db4 463 SUPERFAMILY SSF49899 285 402 2.92E-8 T 30-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily CL1_0386 2f9d28c494b387cd1735550516cef698 236 Pfam PF12840 Helix-turn-helix domain 5 59 1.3E-8 T 30-10-2018 CL1_0386 2f9d28c494b387cd1735550516cef698 236 SMART SM00418 5 86 1.7E-11 T 30-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CL1_0386 2f9d28c494b387cd1735550516cef698 236 Gene3D G3DSA:1.10.10.10 164 232 2.2E-33 T 30-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CL1_0386 2f9d28c494b387cd1735550516cef698 236 SUPERFAMILY SSF46785 152 194 8.35E-5 T 30-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CL1_0386 2f9d28c494b387cd1735550516cef698 236 SUPERFAMILY SSF46785 5 101 5.54E-14 T 30-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CL1_0386 2f9d28c494b387cd1735550516cef698 236 Gene3D G3DSA:1.10.10.10 2 77 6.6E-20 T 30-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CL1_1986 c4fc5efb13023e1dd915dd494248e35f 391 SUPERFAMILY SSF52540 41 163 1.69E-12 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_1986 c4fc5efb13023e1dd915dd494248e35f 391 Pfam PF13173 AAA domain 41 157 7.8E-21 T 30-10-2018 CL1_1243 f233959199026998463ea5252df5fa5b 331 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 57 218 2.6E-25 T 30-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CL1_1243 f233959199026998463ea5252df5fa5b 331 SUPERFAMILY SSF52518 12 318 4.91E-76 T 30-10-2018 IPR029061 Thiamin diphosphate-binding fold CL1_1243 f233959199026998463ea5252df5fa5b 331 Gene3D G3DSA:3.40.50.970 98 321 9.0E-68 T 30-10-2018 CL1_1243 f233959199026998463ea5252df5fa5b 331 Gene3D G3DSA:3.40.50.970 14 97 5.8E-11 T 30-10-2018 CL1_1125 5a77a6998209a2df4f04276015a3f5f2 402 SUPERFAMILY SSF52540 55 303 2.25E-23 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_1125 5a77a6998209a2df4f04276015a3f5f2 402 Gene3D G3DSA:3.40.50.300 47 235 8.2E-10 T 30-10-2018 CL1_0359 54698d76365f40fc031248825e8ce1c4 170 SUPERFAMILY SSF54814 53 96 4.05E-8 T 30-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 CL1_0359 54698d76365f40fc031248825e8ce1c4 170 Gene3D G3DSA:3.30.300.20 49 97 1.1E-9 T 30-10-2018 IPR015946 K homology domain-like, alpha/beta CL1_0359 54698d76365f40fc031248825e8ce1c4 170 Pfam PF13184 NusA-like KH domain 57 124 9.9E-12 T 30-10-2018 IPR025249 KH domain, NusA-like GO:0003723 CL1_0359 54698d76365f40fc031248825e8ce1c4 170 SMART SM00322 57 119 1.4E-4 T 30-10-2018 IPR004087 K Homology domain GO:0003676 CL1_0850 2c88335dcedcde6f9fbeed4ae993613e 1210 Gene3D G3DSA:3.20.110.20 220 498 2.4E-20 T 30-10-2018 CL1_0850 2c88335dcedcde6f9fbeed4ae993613e 1210 Pfam PF03065 Glycosyl hydrolase family 57 258 473 7.1E-11 T 30-10-2018 IPR004300 Glycoside hydrolase family 57, N-terminal domain GO:0003824|GO:0005975 CL1_0850 2c88335dcedcde6f9fbeed4ae993613e 1210 SUPERFAMILY SSF49344 1011 1151 4.71E-7 T 30-10-2018 CL1_0850 2c88335dcedcde6f9fbeed4ae993613e 1210 SUPERFAMILY SSF88713 234 506 1.95E-15 T 30-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CL1_0850 2c88335dcedcde6f9fbeed4ae993613e 1210 SMART SM01066 875 956 2.1E-5 T 30-10-2018 IPR005085 Carbohydrate binding module family 25 GO:2001070 CL1_0850 2c88335dcedcde6f9fbeed4ae993613e 1210 Pfam PF16760 Starch/carbohydrate-binding module (family 53) 878 952 1.7E-9 T 30-10-2018 IPR005085 Carbohydrate binding module family 25 GO:2001070 CL1_0941 c92f7d8575b8464c64da4fb8f19670ce 563 Pfam PF03235 Protein of unknown function DUF262 8 241 1.1E-20 T 30-10-2018 IPR004919 Domain of unknown function DUF262 CL1_0690 3527e7f7bcfcf2a13d5419b0e6459ef2 768 Pfam PF08308 PEGA domain 628 693 9.3E-14 T 30-10-2018 IPR013229 PEGA CL1_0690 3527e7f7bcfcf2a13d5419b0e6459ef2 768 Pfam PF08308 PEGA domain 557 626 7.4E-8 T 30-10-2018 IPR013229 PEGA CL1_0690 3527e7f7bcfcf2a13d5419b0e6459ef2 768 Pfam PF08308 PEGA domain 502 548 5.8E-8 T 30-10-2018 IPR013229 PEGA CL1_1918 06bffa2ceed16398703862ee360cb859 415 PIRSF PIRSF018863 1 415 3.6E-194 T 30-10-2018 IPR014496 Uncharacterised conserved protein UCP018863 CL1_1918 06bffa2ceed16398703862ee360cb859 415 Pfam PF04409 Protein of unknown function (DUF530) 6 256 9.5E-22 T 30-10-2018 IPR007503 Protein of unknown function DUF530 CL1_0483 878823d22b985096b04c2ac26b24fdc1 171 SUPERFAMILY SSF53163 12 156 1.57E-31 T 30-10-2018 IPR023430 Peptidase HybD-like domain superfamily CL1_0483 878823d22b985096b04c2ac26b24fdc1 171 Gene3D G3DSA:3.40.50.1450 9 167 7.5E-41 T 30-10-2018 IPR023430 Peptidase HybD-like domain superfamily CL1_0483 878823d22b985096b04c2ac26b24fdc1 171 Pfam PF01750 Hydrogenase maturation protease 30 131 9.9E-13 T 30-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 CL1_0483 878823d22b985096b04c2ac26b24fdc1 171 TIGRFAM TIGR00072 hydrog_prot: hydrogenase maturation protease 14 153 8.4E-31 T 30-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 CL1_0483 878823d22b985096b04c2ac26b24fdc1 171 PRINTS PR00446 Hydrogen uptake protein signature 13 25 6.4E-7 T 30-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 CL1_0483 878823d22b985096b04c2ac26b24fdc1 171 PRINTS PR00446 Hydrogen uptake protein signature 25 36 6.4E-7 T 30-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 CL1_0483 878823d22b985096b04c2ac26b24fdc1 171 PRINTS PR00446 Hydrogen uptake protein signature 67 77 6.4E-7 T 30-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 CL1_0540 586baa876638afc5ab1f86db99c39dc2 387 Gene3D G3DSA:3.40.50.300 1 183 1.7E-14 T 30-10-2018 CL1_1768 9eb048f9b6b22c393e02bee19d58eb79 67 Pfam PF01954 Protein of unknown function DUF104 1 58 5.8E-9 T 30-10-2018 IPR008203 Uncharacterised protein family UPF0165 CL1_1200 c96af286a25822469356441999216452 277 SUPERFAMILY SSF52540 3 238 2.15E-40 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_1200 c96af286a25822469356441999216452 277 Gene3D G3DSA:3.40.50.300 2 241 2.0E-44 T 30-10-2018 CL1_1200 c96af286a25822469356441999216452 277 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 4 221 5.9E-18 T 30-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain CL1_1178 493dd0640028e634f8d8c64047452955 351 SUPERFAMILY SSF48452 7 181 5.69E-9 T 30-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 CL1_1178 493dd0640028e634f8d8c64047452955 351 Gene3D G3DSA:1.25.40.10 1 351 4.7E-84 T 30-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 CL1_0489 243d7179811f6fc1bf124de6928f74cb 130 Gene3D G3DSA:1.20.120.330 2 125 5.7E-33 T 30-10-2018 CL1_0489 243d7179811f6fc1bf124de6928f74cb 130 SUPERFAMILY SSF81593 8 123 9.02E-8 T 30-10-2018 CL1_0489 243d7179811f6fc1bf124de6928f74cb 130 Pfam PF05168 HEPN domain 5 119 1.4E-24 T 30-10-2018 IPR007842 HEPN domain CL1_0417 2de9e4705b25ca836594bb7157adbb06 240 SUPERFAMILY SSF88713 15 230 2.53E-12 T 30-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CL1_0417 2de9e4705b25ca836594bb7157adbb06 240 Gene3D G3DSA:3.20.20.370 19 234 1.6E-9 T 30-10-2018 CL1_0417 2de9e4705b25ca836594bb7157adbb06 240 Pfam PF10096 Uncharacterized protein conserved in bacteria (DUF2334) 27 225 1.2E-29 T 30-10-2018 IPR018763 Protein of unknown function DUF2334 CL1_1142 006b7671ec7ba9a79e315b407dd51c6e 165 Pfam PF01899 Na+/H+ ion antiporter subunit 4 162 1.4E-39 T 30-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 CL1_1142 006b7671ec7ba9a79e315b407dd51c6e 165 PIRSF PIRSF019239 1 163 1.8E-40 T 30-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 CL1_1078 1939a295759a30dff9d7ed3da52a3446 637 Pfam PF09369 Domain of unknown function (DUF1998) 504 607 1.5E-9 T 30-10-2018 IPR018973 DEAD/DEAH-box helicase, putative CL1_1206 168cf6578e8cd439830342b2708c7801 652 SUPERFAMILY SSF56228 3 228 2.09E-44 T 30-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily CL1_1206 168cf6578e8cd439830342b2708c7801 652 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 4 225 1.8E-40 T 30-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 CL1_1206 168cf6578e8cd439830342b2708c7801 652 Gene3D G3DSA:3.60.9.10 2 228 6.0E-24 T 30-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily CL1_1206 168cf6578e8cd439830342b2708c7801 652 SUPERFAMILY SSF48310 254 650 5.23E-66 T 30-10-2018 IPR036021 Aldehyde ferredoxin oxidoreductase-like, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 CL1_1206 168cf6578e8cd439830342b2708c7801 652 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 271 576 8.1E-18 T 30-10-2018 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 CL1_1206 168cf6578e8cd439830342b2708c7801 652 Gene3D G3DSA:1.10.569.10 280 474 1.5E-12 T 30-10-2018 IPR013984 Aldehyde ferredoxin oxidoreductase, domain 2 CL1_1206 168cf6578e8cd439830342b2708c7801 652 SMART SM00790 1 226 9.8E-71 T 30-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 CL1_0476 8fd4ac6594b152272d013d8f7752b415 319 SUPERFAMILY SSF48452 76 219 5.69E-14 T 30-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 CL1_0476 8fd4ac6594b152272d013d8f7752b415 319 Pfam PF13424 Tetratricopeptide repeat 83 153 3.5E-8 T 30-10-2018 CL1_0476 8fd4ac6594b152272d013d8f7752b415 319 Gene3D G3DSA:1.25.40.10 47 237 8.2E-17 T 30-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 CL1_0476 8fd4ac6594b152272d013d8f7752b415 319 SMART SM00028 81 114 19.0 T 30-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CL1_0476 8fd4ac6594b152272d013d8f7752b415 319 SMART SM00028 121 154 7.5E-4 T 30-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CL1_0763 5f8b94262e74c4c5ff77029a988d5a29 415 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 339 349 - T 30-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site CL1_0763 5f8b94262e74c4c5ff77029a988d5a29 415 SUPERFAMILY SSF52743 99 413 1.44E-82 T 30-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 CL1_0763 5f8b94262e74c4c5ff77029a988d5a29 415 Gene3D G3DSA:3.40.50.200 96 415 1.2E-107 T 30-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 CL1_0763 5f8b94262e74c4c5ff77029a988d5a29 415 SUPERFAMILY SSF54897 35 83 1.13E-6 T 30-10-2018 CL1_0763 5f8b94262e74c4c5ff77029a988d5a29 415 Pfam PF00082 Subtilase family 127 402 3.0E-45 T 30-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CL1_0763 5f8b94262e74c4c5ff77029a988d5a29 415 Gene3D G3DSA:3.30.70.80 21 85 1.8E-22 T 30-10-2018 IPR037045 Peptidase S8 propeptide/proteinase inhibitor I9 superfamily Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 CL1_0763 5f8b94262e74c4c5ff77029a988d5a29 415 PRINTS PR00723 Subtilisin serine protease family (S8) signature 166 179 6.5E-19 T 30-10-2018 IPR015500 Peptidase S8, subtilisin-related CL1_0763 5f8b94262e74c4c5ff77029a988d5a29 415 PRINTS PR00723 Subtilisin serine protease family (S8) signature 123 142 6.5E-19 T 30-10-2018 IPR015500 Peptidase S8, subtilisin-related CL1_0763 5f8b94262e74c4c5ff77029a988d5a29 415 PRINTS PR00723 Subtilisin serine protease family (S8) signature 338 354 6.5E-19 T 30-10-2018 IPR015500 Peptidase S8, subtilisin-related CL1_0228 9c94e0a6f57d064354c711efadf9a2d1 86 Hamap MF_00327 50S ribosomal protein L37Ae [rpl37ae]. 3 71 25.16 T 30-10-2018 IPR002674 Ribosomal protein L37ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 CL1_0228 9c94e0a6f57d064354c711efadf9a2d1 86 Pfam PF01780 Ribosomal L37ae protein family 3 82 1.3E-33 T 30-10-2018 IPR002674 Ribosomal protein L37ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 CL1_0228 9c94e0a6f57d064354c711efadf9a2d1 86 TIGRFAM TIGR00280 eL43_euk_arch: ribosomal protein eL43 1 80 4.6E-37 T 30-10-2018 IPR002674 Ribosomal protein L37ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 CL1_0228 9c94e0a6f57d064354c711efadf9a2d1 86 Gene3D G3DSA:2.20.25.30 9 86 9.8E-32 T 30-10-2018 IPR011331 Ribosomal protein L37ae/L37e GO:0003735|GO:0005622|GO:0005840|GO:0006412 CL1_0228 9c94e0a6f57d064354c711efadf9a2d1 86 SUPERFAMILY SSF57829 10 80 1.1E-28 T 30-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 CL1_0095 2d36f7acef2972d3766c8694a128c8f3 73 ProDom PD052018 AF1456 COIL COILED 14 72 0.009 T 30-10-2018 CL1_1229 924df12a34d27dc54ced0657f2bf76fd 195 Pfam PF01949 Protein of unknown function DUF99 8 188 1.3E-65 T 30-10-2018 IPR002802 Protein of unknown function DUF99 CL1_1229 924df12a34d27dc54ced0657f2bf76fd 195 Hamap MF_00582 UPF0215 protein . 9 189 34.299 T 30-10-2018 IPR002802 Protein of unknown function DUF99 CL1_1229 924df12a34d27dc54ced0657f2bf76fd 195 Gene3D G3DSA:3.30.2170.10 3 195 8.5E-61 T 30-10-2018 CL1_1229 924df12a34d27dc54ced0657f2bf76fd 195 ProDom PD016744 UPF0215 ST0304 TK2033 MA4269 PAE0952 SSO0256 NEQ431 MK0057 PTO0905 TV0037 72 184 3.0E-38 T 30-10-2018 IPR002802 Protein of unknown function DUF99 CL1_1229 924df12a34d27dc54ced0657f2bf76fd 195 PIRSF PIRSF006380 1 195 7.4E-70 T 30-10-2018 IPR002802 Protein of unknown function DUF99 CL1_0556 8e096a7084b1c760d13b0dbb79584e44 194 Gene3D G3DSA:3.40.1120.10 1 193 2.0E-90 T 30-10-2018 IPR024794 Ribosomal protein L15e core domain superfamily GO:0003735|GO:0005840 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0556 8e096a7084b1c760d13b0dbb79584e44 194 ProSitePatterns PS01194 Ribosomal protein L15e signature. 46 69 - T 30-10-2018 IPR020925 Ribosomal protein L15e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0556 8e096a7084b1c760d13b0dbb79584e44 194 SMART SM01384 2 191 8.0E-135 T 30-10-2018 IPR000439 Ribosomal protein L15e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0556 8e096a7084b1c760d13b0dbb79584e44 194 Hamap MF_00256 50S ribosomal protein L15e [rpl15e]. 1 193 43.226 T 30-10-2018 IPR020926 Ribosomal protein L15e, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 CL1_0556 8e096a7084b1c760d13b0dbb79584e44 194 SUPERFAMILY SSF54189 1 191 2.06E-87 T 30-10-2018 IPR012678 Ribosomal protein L23/L15e core domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 CL1_0556 8e096a7084b1c760d13b0dbb79584e44 194 Pfam PF00827 Ribosomal L15 2 189 1.1E-89 T 30-10-2018 IPR000439 Ribosomal protein L15e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0845 11330685a37cf5ed9cf19cd951ad8521 332 Pfam PF14258 Domain of unknown function (DUF4350) 40 107 7.7E-11 T 30-10-2018 IPR025646 Domain of unknown function DUF4350 CL1_1767 9615d9687be1069ead3ef75dc6a617b6 149 SUPERFAMILY SSF88723 1 146 1.18E-20 T 30-10-2018 IPR029060 PIN-like domain superfamily CL1_1767 9615d9687be1069ead3ef75dc6a617b6 149 Gene3D G3DSA:3.40.50.1010 2 148 3.5E-12 T 30-10-2018 CL1_1767 9615d9687be1069ead3ef75dc6a617b6 149 Pfam PF01850 PIN domain 3 143 4.2E-23 T 30-10-2018 IPR002716 PIN domain CL1_1767 9615d9687be1069ead3ef75dc6a617b6 149 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 3 149 10.198 T 30-10-2018 IPR022907 VapC family GO:0004540 CL1_1767 9615d9687be1069ead3ef75dc6a617b6 149 SMART SM00670 1 141 3.2E-16 T 30-10-2018 IPR002716 PIN domain CL1_0262 cca2f31a539997dc3e19ee89969ad520 136 Gene3D G3DSA:2.40.50.140 71 135 1.8E-28 T 30-10-2018 CL1_0262 cca2f31a539997dc3e19ee89969ad520 136 ProSitePatterns PS00302 Eukaryotic initiation factor 5A hypusine signature. 35 42 - T 30-10-2018 IPR019769 Translation elongation factor, IF5A, hypusine site GO:0003723|GO:0003746|GO:0043022|GO:0045901|GO:0045905 CL1_0262 cca2f31a539997dc3e19ee89969ad520 136 Hamap MF_00085 Translation initiation factor 5A [eif5a]. 3 133 34.483 T 30-10-2018 IPR022847 Translation elongation factor IF5A, archaeal CL1_0262 cca2f31a539997dc3e19ee89969ad520 136 TIGRFAM TIGR00037 eIF_5A: translation elongation factor IF5A 4 134 1.9E-47 T 30-10-2018 IPR001884 Translation elongation factor IF5A-like GO:0003723|GO:0003746|GO:0043022|GO:0045901 CL1_0262 cca2f31a539997dc3e19ee89969ad520 136 Pfam PF01287 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold 70 134 5.3E-10 T 30-10-2018 IPR020189 Translation elongation factor, IF5A C-terminal GO:0003723|GO:0003746|GO:0006452|GO:0043022|GO:0045901|GO:0045905 CL1_0262 cca2f31a539997dc3e19ee89969ad520 136 SUPERFAMILY SSF50249 71 133 1.2E-13 T 30-10-2018 IPR012340 Nucleic acid-binding, OB-fold CL1_0262 cca2f31a539997dc3e19ee89969ad520 136 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 9 40 2.2E-4 T 30-10-2018 IPR013185 Translation elongation factor, KOW-like CL1_0262 cca2f31a539997dc3e19ee89969ad520 136 Gene3D G3DSA:2.30.30.30 1 70 5.5E-28 T 30-10-2018 IPR014722 Ribosomal protein L2, domain 2 CL1_0262 cca2f31a539997dc3e19ee89969ad520 136 SMART SM01376 70 134 1.9E-14 T 30-10-2018 IPR020189 Translation elongation factor, IF5A C-terminal GO:0003723|GO:0003746|GO:0006452|GO:0043022|GO:0045901|GO:0045905 CL1_0262 cca2f31a539997dc3e19ee89969ad520 136 PIRSF PIRSF003025 1 136 2.4E-44 T 30-10-2018 IPR001884 Translation elongation factor IF5A-like GO:0003723|GO:0003746|GO:0043022|GO:0045901 CL1_0262 cca2f31a539997dc3e19ee89969ad520 136 SUPERFAMILY SSF50104 5 78 2.16E-20 T 30-10-2018 IPR008991 Translation protein SH3-like domain superfamily CL1_1018 68ee98d494ae103e905fe53a99b17010 283 Pfam PF13559 Domain of unknown function (DUF4129) 209 273 8.3E-10 T 30-10-2018 IPR025403 Domain of unknown function DUF4129 CL1_1428 91734c6a0a2f04868dd1b8a0f4acf6bb 500 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 225 249 6.0E-8 T 30-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CL1_1428 91734c6a0a2f04868dd1b8a0f4acf6bb 500 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 308 327 6.0E-8 T 30-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CL1_1428 91734c6a0a2f04868dd1b8a0f4acf6bb 500 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 156 180 6.0E-8 T 30-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CL1_1428 91734c6a0a2f04868dd1b8a0f4acf6bb 500 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 126 145 6.0E-8 T 30-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CL1_1428 91734c6a0a2f04868dd1b8a0f4acf6bb 500 Pfam PF00361 Proton-conducting membrane transporter 120 374 5.2E-48 T 30-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CL1_1082 dfe072a674cea572e36cb6ad2cb202dc 325 Gene3D G3DSA:1.10.443.10 56 259 4.3E-12 T 30-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 CL1_1082 dfe072a674cea572e36cb6ad2cb202dc 325 Pfam PF00589 Phage integrase family 68 183 6.8E-10 T 30-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CL1_1082 dfe072a674cea572e36cb6ad2cb202dc 325 SUPERFAMILY SSF56349 69 261 1.03E-14 T 30-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CL1_0751 f5e07f40cb68a6b7f66d508236aeb0a9 210 Pfam PF06510 Protein of unknown function (DUF1102) 39 198 3.4E-46 T 30-10-2018 IPR009482 Protein of unknown function DUF1102 CL1_1893 1b17e71392eb1e26a1b5c9b312ac4c06 234 SUPERFAMILY SSF55486 171 219 2.84E-9 T 30-10-2018 CL1_1893 1b17e71392eb1e26a1b5c9b312ac4c06 234 Gene3D G3DSA:3.40.390.10 71 228 1.2E-19 T 30-10-2018 IPR024079 Metallopeptidase, catalytic domain superfamily GO:0008237 CL1_1893 1b17e71392eb1e26a1b5c9b312ac4c06 234 Pfam PF07998 Peptidase family M54 1 142 4.2E-19 T 30-10-2018 IPR012962 Peptidase M54, archaemetzincin GO:0008270 CL1_1893 1b17e71392eb1e26a1b5c9b312ac4c06 234 Pfam PF07998 Peptidase family M54 165 222 1.1E-22 T 30-10-2018 IPR012962 Peptidase M54, archaemetzincin GO:0008270 CL1_0760 0bc3e13746477461c4b117c9529deebd 176 Hamap MF_00590 UPF0218 protein . 5 172 29.494 T 30-10-2018 IPR007164 Protein of unknown function DUF359 CL1_0760 0bc3e13746477461c4b117c9529deebd 176 PIRSF PIRSF006533 1 174 3.3E-55 T 30-10-2018 IPR007164 Protein of unknown function DUF359 CL1_0760 0bc3e13746477461c4b117c9529deebd 176 Pfam PF04019 Protein of unknown function (DUF359) 49 170 6.1E-39 T 30-10-2018 IPR007164 Protein of unknown function DUF359 CL1_0730 6e55a5bb9493f01904ead5a0ea3dc85e 213 PIRSF PIRSF019202 1 213 1.0E-46 T 30-10-2018 IPR007366 Protein of unknown function DUF432 CL1_0730 6e55a5bb9493f01904ead5a0ea3dc85e 213 Pfam PF04254 Protein of unknown function (DUF432) 51 165 1.6E-27 T 30-10-2018 IPR007366 Protein of unknown function DUF432 CL1_1177 b51f242d5b900f06d3cbe201b7f88221 311 Pfam PF01244 Membrane dipeptidase (Peptidase family M19) 2 307 2.2E-93 T 30-10-2018 IPR008257 Peptidase M19 GO:0006508|GO:0016805 MetaCyc: PWY-7533|Reactome: R-HSA-2142691|Reactome: R-HSA-5423646 CL1_1177 b51f242d5b900f06d3cbe201b7f88221 311 SUPERFAMILY SSF51556 1 310 1.75E-75 T 30-10-2018 IPR032466 Metal-dependent hydrolase CL1_1177 b51f242d5b900f06d3cbe201b7f88221 311 Gene3D G3DSA:3.20.20.140 1 311 2.6E-94 T 30-10-2018 CL1_1114 b453f20d2537448617c591e84c7233fe 1307 SUPERFAMILY SSF103647 547 607 2.22E-6 T 30-10-2018 IPR028974 TSP type-3 repeat GO:0005509 Reactome: R-HSA-186797 CL1_1114 b453f20d2537448617c591e84c7233fe 1307 ProSitePatterns PS00018 EF-hand calcium-binding domain. 587 599 - T 30-10-2018 IPR018247 EF-Hand 1, calcium-binding site CL1_1114 b453f20d2537448617c591e84c7233fe 1307 Gene3D G3DSA:2.60.40.10 290 371 3.0E-5 T 30-10-2018 IPR013783 Immunoglobulin-like fold CL1_0878 e98c3a176a83de833cbf6d3cd6c08241 86 Pfam PF02697 Putative antitoxin 13 79 6.1E-23 T 30-10-2018 IPR003847 Putative antitoxin CL1_0878 e98c3a176a83de833cbf6d3cd6c08241 86 Hamap MF_00794 Putative antitoxin . 12 82 16.857 T 30-10-2018 IPR003847 Putative antitoxin CL1_0878 e98c3a176a83de833cbf6d3cd6c08241 86 ProDom PD188822 UPF0330 AF1997 ST1125.1 AF1689 AF1478 C1_0043 PYRAB04040 PF1222 MM2475 MA1514 13 61 1.0E-19 T 30-10-2018 IPR003847 Putative antitoxin CL1_1941 a7872f30a75a5f207de04b1f0160446c 293 SUPERFAMILY SSF52540 91 287 1.22E-13 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_1941 a7872f30a75a5f207de04b1f0160446c 293 Pfam PF03477 ATP cone domain 12 86 4.3E-11 T 30-10-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 CL1_1941 a7872f30a75a5f207de04b1f0160446c 293 Hamap MF_00769 2-phosphoglycerate kinase [pgk2]. 5 293 43.984 T 30-10-2018 IPR020872 2-phosphoglycerate kinase GO:0016774 CL1_0425 e8c304b09bc96a5c0e01f862987fa013 418 Gene3D G3DSA:3.50.50.60 10 303 4.6E-53 T 30-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily CL1_0425 e8c304b09bc96a5c0e01f862987fa013 418 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 255 269 4.9E-19 T 30-10-2018 CL1_0425 e8c304b09bc96a5c0e01f862987fa013 418 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 164 189 4.9E-19 T 30-10-2018 CL1_0425 e8c304b09bc96a5c0e01f862987fa013 418 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 11 33 4.9E-19 T 30-10-2018 CL1_0425 e8c304b09bc96a5c0e01f862987fa013 418 SUPERFAMILY SSF51905 7 327 9.77E-42 T 30-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily CL1_0425 e8c304b09bc96a5c0e01f862987fa013 418 Gene3D G3DSA:3.50.50.60 129 262 4.6E-53 T 30-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily CL1_0425 e8c304b09bc96a5c0e01f862987fa013 418 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 12 31 5.7E-26 T 30-10-2018 CL1_0425 e8c304b09bc96a5c0e01f862987fa013 418 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 117 135 5.7E-26 T 30-10-2018 CL1_0425 e8c304b09bc96a5c0e01f862987fa013 418 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 164 182 5.7E-26 T 30-10-2018 CL1_0425 e8c304b09bc96a5c0e01f862987fa013 418 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 254 270 5.7E-26 T 30-10-2018 CL1_0425 e8c304b09bc96a5c0e01f862987fa013 418 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 282 304 5.7E-26 T 30-10-2018 CL1_0425 e8c304b09bc96a5c0e01f862987fa013 418 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 10 303 5.7E-29 T 30-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CL1_1136 5b211679775867185b55eb5f49ae7bf1 119 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 6 115 4.2E-26 T 30-10-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like CL1_0401 60675bff9e9d460af89b81df170dc2ea 216 Gene3D G3DSA:3.40.50.790 59 150 9.7E-78 T 30-10-2018 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich CL1_0401 60675bff9e9d460af89b81df170dc2ea 216 PIRSF PIRSF002155 1 216 1.8E-67 T 30-10-2018 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0401 60675bff9e9d460af89b81df170dc2ea 216 Gene3D G3DSA:3.30.190.20 13 213 9.7E-78 T 30-10-2018 CL1_0401 60675bff9e9d460af89b81df170dc2ea 216 Hamap MF_01318_A 50S ribosomal protein L1 [rplA]. 4 215 37.146 T 30-10-2018 IPR023669 Ribosomal protein L1, archaea GO:0003723|GO:0003735|GO:0006412|GO:0015934 CL1_0401 60675bff9e9d460af89b81df170dc2ea 216 SUPERFAMILY SSF56808 7 214 5.76E-66 T 30-10-2018 IPR023674 Ribosomal protein L1-like CL1_0401 60675bff9e9d460af89b81df170dc2ea 216 ProSitePatterns PS01199 Ribosomal protein L1 signature. 114 133 - T 30-10-2018 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0401 60675bff9e9d460af89b81df170dc2ea 216 Pfam PF00687 Ribosomal protein L1p/L10e family 21 210 2.2E-49 T 30-10-2018 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein CL1_0935 c2de95fb1d8689f162726ec22263a126 659 Pfam PF01496 V-type ATPase 116kDa subunit family 555 647 2.3E-12 T 30-10-2018 IPR002490 V-type ATPase, V0 complex, 116kDa subunit family GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 CL1_0935 c2de95fb1d8689f162726ec22263a126 659 Pfam PF01496 V-type ATPase 116kDa subunit family 147 441 2.1E-22 T 30-10-2018 IPR002490 V-type ATPase, V0 complex, 116kDa subunit family GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 CL1_0935 c2de95fb1d8689f162726ec22263a126 659 Gene3D G3DSA:1.20.1460.20 47 290 7.8E-24 T 30-10-2018 CL1_0935 c2de95fb1d8689f162726ec22263a126 659 Gene3D G3DSA:3.30.70.2750 149 224 7.8E-24 T 30-10-2018 CL1_0935 c2de95fb1d8689f162726ec22263a126 659 Gene3D G3DSA:3.30.70.2170 7 310 7.8E-24 T 30-10-2018 CL1_1752 a7f803fbeb3bfb17d16962b16b005465 413 Pfam PF09376 NurA domain 46 378 3.1E-36 T 30-10-2018 IPR018977 NurA domain CL1_1752 a7f803fbeb3bfb17d16962b16b005465 413 SMART SM00933 45 378 2.7E-14 T 30-10-2018 IPR018977 NurA domain CL1_0947 cf4d9b88cadebcbd9dff7973f052ccb5 165 Gene3D G3DSA:2.30.130.10 92 163 1.6E-20 T 30-10-2018 IPR036974 PUA domain superfamily GO:0003723 CL1_0947 cf4d9b88cadebcbd9dff7973f052ccb5 165 Pfam PF03657 Uncharacterised protein family (UPF0113) 4 163 1.2E-11 T 30-10-2018 IPR005155 Ribosome biogenesis factor NIP7-like Reactome: R-HSA-6791226 CL1_0947 cf4d9b88cadebcbd9dff7973f052ccb5 165 Gene3D G3DSA:3.10.450.220 1 91 2.3E-43 T 30-10-2018 CL1_0939 2a395a7f13b24926294518333fd88d06 304 Hamap MF_01464_A Protein-export membrane protein SecF [secF]. 28 300 25.837 T 30-10-2018 IPR024921 Protein-export membrane protein SecF, archaeal GO:0016021|GO:0065002 CL1_0939 2a395a7f13b24926294518333fd88d06 304 SUPERFAMILY SSF82866 123 290 2.88E-24 T 30-10-2018 CL1_0939 2a395a7f13b24926294518333fd88d06 304 Gene3D G3DSA:1.20.1640.10 116 303 3.1E-15 T 30-10-2018 CL1_0939 2a395a7f13b24926294518333fd88d06 304 Pfam PF02355 Protein export membrane protein 124 295 3.0E-31 T 30-10-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial CL1_1268 e5cb4e1ea4be2b19fa13a9ef91d03197 428 Pfam PF03600 Citrate transporter 18 368 4.3E-53 T 30-10-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 CL1_1268 e5cb4e1ea4be2b19fa13a9ef91d03197 428 PRINTS PR00758 Arsenical pump membrane protein signature 324 346 6.7E-16 T 30-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CL1_1268 e5cb4e1ea4be2b19fa13a9ef91d03197 428 PRINTS PR00758 Arsenical pump membrane protein signature 223 248 6.7E-16 T 30-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CL1_1268 e5cb4e1ea4be2b19fa13a9ef91d03197 428 PRINTS PR00758 Arsenical pump membrane protein signature 397 421 6.7E-16 T 30-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CL1_1268 e5cb4e1ea4be2b19fa13a9ef91d03197 428 PRINTS PR00758 Arsenical pump membrane protein signature 364 389 6.7E-16 T 30-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CL1_1268 e5cb4e1ea4be2b19fa13a9ef91d03197 428 PRINTS PR00758 Arsenical pump membrane protein signature 280 304 6.7E-16 T 30-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CL1_1268 e5cb4e1ea4be2b19fa13a9ef91d03197 428 PRINTS PR00758 Arsenical pump membrane protein signature 103 127 6.7E-16 T 30-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CL1_0325 94a8d75894b9865050b9529f06eeb7e7 268 SUPERFAMILY SSF51658 1 238 3.27E-27 T 30-10-2018 IPR036237 Xylose isomerase-like superfamily CL1_0325 94a8d75894b9865050b9529f06eeb7e7 268 Pfam PF01261 Xylose isomerase-like TIM barrel 30 228 1.4E-14 T 30-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CL1_0325 94a8d75894b9865050b9529f06eeb7e7 268 Gene3D G3DSA:3.20.20.150 1 255 1.5E-25 T 30-10-2018 CL1_1267 985b28d244b6ebda14ccdd4f64aac11b 182 Gene3D G3DSA:3.40.50.620 45 182 1.2E-8 T 30-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CL1_1267 985b28d244b6ebda14ccdd4f64aac11b 182 SUPERFAMILY SSF52402 63 181 6.2E-8 T 30-10-2018 CL1_0849 e3322a1273c49070da9392c08db09615 277 ProSitePatterns PS00989 Clathrin adaptor complexes small chain signature. 20 30 - T 30-10-2018 IPR000804 Clathrin adaptor complex, small chain GO:0006886|GO:0016192|GO:0030117 CL1_0849 e3322a1273c49070da9392c08db09615 277 Pfam PF09721 Transmembrane exosortase (Exosortase_EpsH) 27 255 4.1E-19 T 30-10-2018 IPR019127 Exosortase CL1_0849 e3322a1273c49070da9392c08db09615 277 TIGRFAM TIGR04178 exo_archaeo: exosortase/archaeosortase family protein 167 256 6.3E-15 T 30-10-2018 IPR026392 Exosortase/Archaeosortase domain CL1_0127 1d9c228ab45c84a6b44527baa7d903ec 208 Gene3D G3DSA:1.20.58.2140 3 201 2.5E-62 T 30-10-2018 CL1_0127 1d9c228ab45c84a6b44527baa7d903ec 208 Pfam PF01997 Translin family 21 177 1.3E-6 T 30-10-2018 IPR002848 Translin family GO:0043565 Reactome: R-HSA-426486 CL1_0127 1d9c228ab45c84a6b44527baa7d903ec 208 SUPERFAMILY SSF74784 1 182 2.48E-33 T 30-10-2018 IPR036081 Translin superfamily GO:0043565 Reactome: R-HSA-426486 CL1_0106 4b7a779e4fe8baea7859da246b75a515 75 SMART SM00899 3 74 4.9E-19 T 30-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 CL1_0106 4b7a779e4fe8baea7859da246b75a515 75 Gene3D G3DSA:2.30.30.90 3 75 3.6E-20 T 30-10-2018 IPR038157 Ferrous iron transporter, core domain CL1_0106 4b7a779e4fe8baea7859da246b75a515 75 SUPERFAMILY SSF50037 5 74 2.98E-16 T 30-10-2018 IPR008988 Transcriptional repressor, C-terminal CL1_0106 4b7a779e4fe8baea7859da246b75a515 75 Pfam PF04023 FeoA domain 3 73 1.2E-18 T 30-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 CL1_1571 8fef08607f3490efed991933e4a6f925 562 SUPERFAMILY SSF51703 9 556 5.89E-231 T 30-10-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CL1_1571 8fef08607f3490efed991933e4a6f925 562 Pfam PF01642 Methylmalonyl-CoA mutase 39 554 3.6E-241 T 30-10-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CL1_1571 8fef08607f3490efed991933e4a6f925 562 TIGRFAM TIGR00641 acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain 37 560 2.6E-290 T 30-10-2018 IPR006098 Methylmalonyl-CoA mutase, alpha chain, catalytic GO:0004494|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CL1_1571 8fef08607f3490efed991933e4a6f925 562 Gene3D G3DSA:3.20.20.240 1 562 9.2E-270 T 30-10-2018 CL1_1940 ae367fc576b4d2a354bfd2f9ce7fd4f8 434 Hamap MF_01908 Cyclic 2,3-diphosphoglycerate synthetase [cpgS]. 3 434 47.396 T 30-10-2018 IPR016557 Cyclic 2, 3-diphospoglycerate synthetase GO:0005737|GO:0006094|GO:0036356 CL1_1940 ae367fc576b4d2a354bfd2f9ce7fd4f8 434 PIRSF PIRSF009445 2 433 8.7E-181 T 30-10-2018 IPR016557 Cyclic 2, 3-diphospoglycerate synthetase GO:0005737|GO:0006094|GO:0036356 CL1_1940 ae367fc576b4d2a354bfd2f9ce7fd4f8 434 Gene3D G3DSA:3.40.50.300 190 320 2.7E-5 T 30-10-2018 CL1_2001 36bca4dd96f983b674df6575f94af878 300 Pfam PF13173 AAA domain 6 67 3.4E-11 T 30-10-2018 CL1_1537 0fb8ec342cd128b129ea2a8a6d4e9fd8 535 Pfam PF01841 Transglutaminase-like superfamily 291 387 3.4E-7 T 30-10-2018 IPR002931 Transglutaminase-like CL1_1537 0fb8ec342cd128b129ea2a8a6d4e9fd8 535 Gene3D G3DSA:3.10.620.30 262 409 1.8E-6 T 30-10-2018 CL1_1537 0fb8ec342cd128b129ea2a8a6d4e9fd8 535 SUPERFAMILY SSF54001 281 444 2.94E-10 T 30-10-2018 IPR038765 Papain-like cysteine peptidase superfamily CL1_1824 656985887efce33678faab0d1f256513 232 Pfam PF00977 Histidine biosynthesis protein 3 217 1.1E-54 T 30-10-2018 IPR006062 Histidine biosynthesis GO:0000105 CL1_1824 656985887efce33678faab0d1f256513 232 SUPERFAMILY SSF51366 1 224 1.88E-49 T 30-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 CL1_1824 656985887efce33678faab0d1f256513 232 Gene3D G3DSA:3.20.20.70 1 228 6.7E-66 T 30-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CL1_1824 656985887efce33678faab0d1f256513 232 Hamap MF_01014 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [hisA]. 2 225 29.113 T 30-10-2018 IPR023016 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 CL1_0271 2434df163639526dd05dd29f601b4417 279 TIGRFAM TIGR00374 TIGR00374: TIGR00374 family protein 1 129 1.5E-18 T 30-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD CL1_0271 2434df163639526dd05dd29f601b4417 279 TIGRFAM TIGR00374 TIGR00374: TIGR00374 family protein 167 265 3.0E-19 T 30-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD CL1_0271 2434df163639526dd05dd29f601b4417 279 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 2 260 5.0E-40 T 30-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD CL1_1645 5f4f95487ebad962ecb287064b648850 343 PIRSF PIRSF000112 1 340 1.4E-67 T 30-10-2018 IPR016205 Glycerol dehydrogenase GO:0016614|GO:0046872|GO:0055114 KEGG: 00564+1.1.1.261|MetaCyc: PWY-6349 CL1_1645 5f4f95487ebad962ecb287064b648850 343 SUPERFAMILY SSF56796 2 336 3.14E-73 T 30-10-2018 CL1_1645 5f4f95487ebad962ecb287064b648850 343 Hamap MF_00497_A Glycerol-1-phosphate dehydrogenase [NAD(P)+] [egsA]. 1 343 45.39 T 30-10-2018 IPR023002 Glycerol-1-phosphate dehydrogenase, archaea GO:0050492|GO:0055114 KEGG: 00564+1.1.1.261|MetaCyc: PWY-6349 CL1_1645 5f4f95487ebad962ecb287064b648850 343 Pfam PF13685 Iron-containing alcohol dehydrogenase 10 265 3.6E-74 T 30-10-2018 IPR032837 Glycerol-1-phosphate dehydrogenase KEGG: 00564+1.1.1.261|MetaCyc: PWY-6349 CL1_1645 5f4f95487ebad962ecb287064b648850 343 Gene3D G3DSA:3.40.50.1970 1 152 9.8E-35 T 30-10-2018 CL1_1645 5f4f95487ebad962ecb287064b648850 343 Gene3D G3DSA:1.20.1090.10 153 342 5.9E-67 T 30-10-2018 CL1_1418 8975a97d7b65beb142649c8af2f8eba0 334 Gene3D G3DSA:1.10.10.10 266 330 7.8E-10 T 30-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CL1_1418 8975a97d7b65beb142649c8af2f8eba0 334 SUPERFAMILY SSF46785 267 330 7.27E-11 T 30-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CL1_1418 8975a97d7b65beb142649c8af2f8eba0 334 Pfam PF04122 Putative cell wall binding repeat 2 114 175 2.1E-6 T 30-10-2018 IPR007253 Putative cell wall binding repeat 2 CL1_0863 6a61f006d9c9d9ffa1de1de0a28cfd65 154 Gene3D G3DSA:3.40.50.2020 1 154 5.9E-53 T 30-10-2018 CL1_0863 6a61f006d9c9d9ffa1de1de0a28cfd65 154 SUPERFAMILY SSF53271 2 146 1.57E-35 T 30-10-2018 IPR029057 Phosphoribosyltransferase-like CL1_0863 6a61f006d9c9d9ffa1de1de0a28cfd65 154 Pfam PF00156 Phosphoribosyl transferase domain 13 150 2.6E-27 T 30-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CL1_1956 3bf0269c4568556dd3c8f02355eae30d 308 TIGRFAM TIGR01903 cas5_csm4: CRISPR type III-A/MTUBE-associated RAMP protein Csm4 4 295 1.0E-48 T 30-10-2018 IPR005510 CRISPR type III-associated RAMP protein Csm4 CL1_0855 6147e1be19efcc68b1c577cbe17ad84c 334 Gene3D G3DSA:3.40.720.10 66 297 1.7E-8 T 30-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 CL1_0855 6147e1be19efcc68b1c577cbe17ad84c 334 SUPERFAMILY SSF53649 99 265 1.07E-6 T 30-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 CL1_1185 569374dddad1b97aa3400142370f03d4 187 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 8 180 9.1E-49 T 30-10-2018 IPR001303 Class II aldolase/adducin N-terminal CL1_1185 569374dddad1b97aa3400142370f03d4 187 SUPERFAMILY SSF53639 3 183 8.63E-56 T 30-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily CL1_1185 569374dddad1b97aa3400142370f03d4 187 Gene3D G3DSA:3.40.225.10 2 186 3.2E-61 T 30-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily CL1_1185 569374dddad1b97aa3400142370f03d4 187 SMART SM01007 7 181 3.1E-59 T 30-10-2018 IPR001303 Class II aldolase/adducin N-terminal CL1_0188 b043a0d432190c65bb559a65bfc169de 419 SMART SM00729 115 333 2.0E-15 T 30-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 CL1_0188 b043a0d432190c65bb559a65bfc169de 419 Pfam PF04055 Radical SAM superfamily 123 287 2.7E-28 T 30-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CL1_0188 b043a0d432190c65bb559a65bfc169de 419 SUPERFAMILY SSF102114 109 335 1.44E-39 T 30-10-2018 CL1_0188 b043a0d432190c65bb559a65bfc169de 419 Gene3D G3DSA:3.20.20.70 111 357 3.3E-39 T 30-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CL1_0350 c419809db6cab3db9e6a373a572ecb04 126 Hamap MF_01223 UPF0212 protein . 1 112 32.377 T 30-10-2018 IPR007564 Uncharacterised protein family UPF0212 CL1_0350 c419809db6cab3db9e6a373a572ecb04 126 Pfam PF04475 Protein of unknown function (DUF555) 3 104 2.9E-40 T 30-10-2018 IPR007564 Uncharacterised protein family UPF0212 CL1_0350 c419809db6cab3db9e6a373a572ecb04 126 ProDom PD020367 UPF0212 RRNAC1165 RRNAC0441 AF0282 VNG1264C MJ0068 PYRAB08340 PH1312 MA1372 TK1194 1 102 2.0E-51 T 30-10-2018 IPR007564 Uncharacterised protein family UPF0212 CL1_0350 c419809db6cab3db9e6a373a572ecb04 126 PIRSF PIRSF016934 1 122 5.5E-53 T 30-10-2018 IPR007564 Uncharacterised protein family UPF0212 CL1_1455 1dd9caa9b1c5ef7af9e9a0fa954dd22f 139 Gene3D G3DSA:3.30.1440.10 3 138 9.9E-45 T 30-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_1455 1dd9caa9b1c5ef7af9e9a0fa954dd22f 139 Hamap MF_01112 UPF0201 protein . 7 136 25.303 T 30-10-2018 IPR002739 Uncharacterised protein family UPF0201 CL1_1455 1dd9caa9b1c5ef7af9e9a0fa954dd22f 139 Pfam PF01877 RNA binding 8 117 6.0E-17 T 30-10-2018 IPR002739 Uncharacterised protein family UPF0201 CL1_1455 1dd9caa9b1c5ef7af9e9a0fa954dd22f 139 SUPERFAMILY SSF55282 8 138 4.41E-40 T 30-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_0830 ea9ddcff09c29d3a33a0ed5a8dda8f7d 358 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 25 352 4.5E-117 T 30-10-2018 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 CL1_0830 ea9ddcff09c29d3a33a0ed5a8dda8f7d 358 TIGRFAM TIGR00236 wecB: UDP-N-acetylglucosamine 2-epimerase 1 353 1.9E-114 T 30-10-2018 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 CL1_0830 ea9ddcff09c29d3a33a0ed5a8dda8f7d 358 Gene3D G3DSA:3.40.50.2000 6 350 2.6E-137 T 30-10-2018 CL1_0830 ea9ddcff09c29d3a33a0ed5a8dda8f7d 358 SUPERFAMILY SSF53756 1 354 1.65E-117 T 30-10-2018 CL1_0830 ea9ddcff09c29d3a33a0ed5a8dda8f7d 358 Gene3D G3DSA:3.40.50.2000 182 340 2.6E-137 T 30-10-2018 CL1_1345 3ca79d8571aad6c54cb2af38f30d5f66 260 Gene3D G3DSA:3.30.2010.10 49 132 1.2E-17 T 30-10-2018 CL1_1345 3ca79d8571aad6c54cb2af38f30d5f66 260 Pfam PF01435 Peptidase family M48 57 244 5.5E-22 T 30-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 CL1_0951 e1346363a6cac38207bf48957f033f95 185 Pfam PF03729 Short repeat of unknown function (DUF308) 78 141 1.3E-8 T 30-10-2018 IPR005325 Protein of unknown function DUF308, membrane CL1_0951 e1346363a6cac38207bf48957f033f95 185 Pfam PF03729 Short repeat of unknown function (DUF308) 16 85 2.6E-11 T 30-10-2018 IPR005325 Protein of unknown function DUF308, membrane CL1_1321 125497d73d2e1ae7977c8e602dc6adcf 211 SUPERFAMILY SSF56281 1 197 9.17E-38 T 30-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like CL1_1321 125497d73d2e1ae7977c8e602dc6adcf 211 Pfam PF13483 Beta-lactamase superfamily domain 2 175 1.4E-28 T 30-10-2018 CL1_1321 125497d73d2e1ae7977c8e602dc6adcf 211 SMART SM00849 7 175 3.3E-20 T 30-10-2018 IPR001279 Metallo-beta-lactamase CL1_1321 125497d73d2e1ae7977c8e602dc6adcf 211 Gene3D G3DSA:3.60.15.10 1 201 5.0E-48 T 30-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like CL1_0422 8cd178a4cafe0ae9f04a79139285e2dc 233 Gene3D G3DSA:3.20.20.190 1 233 1.5E-88 T 30-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 CL1_0422 8cd178a4cafe0ae9f04a79139285e2dc 233 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 3 197 2.3E-28 T 30-10-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 CL1_0422 8cd178a4cafe0ae9f04a79139285e2dc 233 SUPERFAMILY SSF51695 3 199 4.71E-52 T 30-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 CL1_0261 560ce528838e8bc4078a4f4d7eb0ba04 459 SUPERFAMILY SSF161070 13 430 7.45E-8 T 30-10-2018 IPR037272 Sodium:neurotransmitter symporter superfamily GO:0005328 CL1_1666 a81310ac9ccc732175fe94ff3333e0e5 253 Gene3D G3DSA:3.30.470.20 17 232 2.5E-91 T 30-10-2018 CL1_1666 a81310ac9ccc732175fe94ff3333e0e5 253 Pfam PF13549 ATP-grasp domain 12 234 7.0E-81 T 30-10-2018 CL1_1666 a81310ac9ccc732175fe94ff3333e0e5 253 Gene3D G3DSA:3.30.1490.20 38 115 2.5E-91 T 30-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 CL1_1666 a81310ac9ccc732175fe94ff3333e0e5 253 SUPERFAMILY SSF56059 19 236 6.01E-46 T 30-10-2018 CL1_0126 a10ee361a2e196ab6684e24bd17f5e5f 405 Gene3D G3DSA:3.30.300.340 18 286 4.2E-171 T 30-10-2018 CL1_0126 a10ee361a2e196ab6684e24bd17f5e5f 405 Hamap MF_00136 S-adenosylmethionine synthase [mat]. 5 405 52.212 T 30-10-2018 IPR002795 S-adenosylmethionine synthetase, archaea GO:0004478|GO:0005524|GO:0006730 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912 CL1_0126 a10ee361a2e196ab6684e24bd17f5e5f 405 Gene3D G3DSA:3.30.300.10 30 154 4.2E-171 T 30-10-2018 CL1_0126 a10ee361a2e196ab6684e24bd17f5e5f 405 Gene3D G3DSA:3.30.300.280 16 398 4.2E-171 T 30-10-2018 CL1_0126 a10ee361a2e196ab6684e24bd17f5e5f 405 Pfam PF01941 S-adenosylmethionine synthetase (AdoMet synthetase) 6 401 6.5E-180 T 30-10-2018 IPR027790 S-adenosylmethionine synthase KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912 CL1_0126 a10ee361a2e196ab6684e24bd17f5e5f 405 ProDom PD011777 SYNTHETASE TRANSFERASE METHIONINE ADENOSYLTRANSFERASE S-ADENOSYLMETHIONINE NUCLEOTIDE-BINDING METABOLISM ATP-BINDING MAGNESIUM ONE-CARBON 21 405 0.0 T 30-10-2018 CL1_0411 b00ecae1ce0cc473082496d46bf84247 429 SUPERFAMILY SSF161070 11 348 4.05E-9 T 30-10-2018 IPR037272 Sodium:neurotransmitter symporter superfamily GO:0005328 CL1_1143 2b29ebefedee53ea48442ddb7bcb905e 150 Pfam PF13247 4Fe-4S dicluster domain 41 131 3.7E-24 T 30-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CL1_1143 2b29ebefedee53ea48442ddb7bcb905e 150 Gene3D G3DSA:3.30.70.20 35 150 2.2E-35 T 30-10-2018 CL1_1143 2b29ebefedee53ea48442ddb7bcb905e 150 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 77 88 - T 30-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CL1_1143 2b29ebefedee53ea48442ddb7bcb905e 150 SUPERFAMILY SSF54862 3 133 3.56E-49 T 30-10-2018 CL1_1687 8a4ca52be2e017321d34283ae6c40457 479 Gene3D G3DSA:3.40.190.10 84 310 4.9E-35 T 30-10-2018 CL1_1687 8a4ca52be2e017321d34283ae6c40457 479 Gene3D G3DSA:3.40.190.10 149 268 4.9E-35 T 30-10-2018 CL1_1687 8a4ca52be2e017321d34283ae6c40457 479 Pfam PF13416 Bacterial extracellular solute-binding protein 86 315 9.4E-19 T 30-10-2018 IPR006059 Bacterial extracellular solute-binding protein CL1_1687 8a4ca52be2e017321d34283ae6c40457 479 SUPERFAMILY SSF53850 83 321 3.42E-39 T 30-10-2018 CL1_0899 c7a0cc8b91e12f1db07ae12d56fb0641 102 Gene3D G3DSA:3.30.720.70 1 102 2.4E-45 T 30-10-2018 CL1_0841 57a5d88facc0523429602ac215e5fc7f 319 SUPERFAMILY SSF51735 1 314 2.72E-83 T 30-10-2018 IPR036291 NAD(P)-binding domain superfamily CL1_0841 57a5d88facc0523429602ac215e5fc7f 319 Gene3D G3DSA:3.40.50.720 1 179 5.0E-51 T 30-10-2018 CL1_0841 57a5d88facc0523429602ac215e5fc7f 319 Gene3D G3DSA:3.90.25.10 226 318 5.2E-26 T 30-10-2018 CL1_0841 57a5d88facc0523429602ac215e5fc7f 319 Gene3D G3DSA:3.90.25.10 180 225 1.5E-14 T 30-10-2018 CL1_0841 57a5d88facc0523429602ac215e5fc7f 319 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 241 1.2E-55 T 30-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CL1_1191 b3a40d1463917dd10018b9ae4ab59b49 99 Gene3D G3DSA:3.30.70.1750 3 99 2.8E-31 T 30-10-2018 CL1_1191 b3a40d1463917dd10018b9ae4ab59b49 99 Pfam PF11491 Protein of unknown function (DUF3213) 14 96 3.8E-37 T 30-10-2018 IPR021583 Protein of unknown function DUF3213 CL1_2008 0fb8db14c6628547b26172929aa07d74 364 Pfam PF05763 Protein of unknown function (DUF835) 236 362 5.7E-27 T 30-10-2018 IPR008553 Domain of unknown function DUF835 CL1_1762 ecf45127a2c4566a6e023332689e505c 351 Pfam PF01546 Peptidase family M20/M25/M40 64 343 7.4E-26 T 30-10-2018 IPR002933 Peptidase M20 GO:0016787 CL1_1762 ecf45127a2c4566a6e023332689e505c 351 Gene3D G3DSA:3.30.70.360 155 264 4.9E-61 T 30-10-2018 CL1_1762 ecf45127a2c4566a6e023332689e505c 351 Pfam PF07687 Peptidase dimerisation domain 152 254 7.2E-9 T 30-10-2018 IPR011650 Peptidase M20, dimerisation domain CL1_1762 ecf45127a2c4566a6e023332689e505c 351 SUPERFAMILY SSF53187 8 343 2.06E-40 T 30-10-2018 CL1_1762 ecf45127a2c4566a6e023332689e505c 351 Gene3D G3DSA:3.40.630.10 14 336 4.9E-61 T 30-10-2018 CL1_1762 ecf45127a2c4566a6e023332689e505c 351 SUPERFAMILY SSF55031 155 270 2.99E-10 T 30-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain CL1_1762 ecf45127a2c4566a6e023332689e505c 351 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 87 124 - T 30-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 CL1_1175 3ed1ebbece347f5c250a2dc9b75fb610 465 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 304 385 4.3E-7 T 30-10-2018 IPR007404 LexA-binding, inner membrane-associated putative hydrolase CL1_1602 a08e535554e1ca01653fac038f102642 247 SUPERFAMILY SSF52540 1 238 3.6E-38 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_1602 a08e535554e1ca01653fac038f102642 247 Gene3D G3DSA:3.40.50.300 1 243 1.4E-58 T 30-10-2018 CL1_1602 a08e535554e1ca01653fac038f102642 247 Pfam PF03029 Conserved hypothetical ATP binding protein 6 239 5.1E-51 T 30-10-2018 IPR004130 GPN-loop GTPase CL1_1361 870cf8bd88379e8ec54c0030bc6ee6d9 260 ProDom PD016827 ARCHAEA ST0532 APE1937 VNG0250C MM2281 PAE3406 AF0927 UNCHARACTERIZED C3_0043 MJ0209 67 251 4.0E-90 T 30-10-2018 IPR002855 Phosphopantoate/pantothenate synthetase CL1_1361 870cf8bd88379e8ec54c0030bc6ee6d9 260 Pfam PF02006 Phosphopantothenate/pantothenate synthetase 66 238 4.1E-78 T 30-10-2018 IPR002855 Phosphopantoate/pantothenate synthetase CL1_1361 870cf8bd88379e8ec54c0030bc6ee6d9 260 Gene3D G3DSA:3.40.50.12640 1 260 6.2E-121 T 30-10-2018 IPR038138 Phosphopantoate/pantothenate synthetase superfamily CL1_1361 870cf8bd88379e8ec54c0030bc6ee6d9 260 PIRSF PIRSF004853 1 252 5.7E-117 T 30-10-2018 IPR002855 Phosphopantoate/pantothenate synthetase CL1_0396 e423499397ab93d4ce084cb47a4c9143 272 Pfam PF04414 D-aminoacyl-tRNA deacylase 69 269 9.9E-68 T 30-10-2018 IPR007508 D-aminoacyl-tRNA deacylase DtdA GO:0016788|GO:0051499 CL1_0396 e423499397ab93d4ce084cb47a4c9143 272 PIRSF PIRSF016210 1 272 3.2E-84 T 30-10-2018 IPR018033 D-aminoacyl-tRNA deacylase, archaea GO:0016788|GO:0019478|GO:0051499 CL1_0396 e423499397ab93d4ce084cb47a4c9143 272 Hamap MF_00562 D-aminoacyl-tRNA deacylase [dtdA]. 1 271 34.974 T 30-10-2018 IPR018033 D-aminoacyl-tRNA deacylase, archaea GO:0016788|GO:0019478|GO:0051499 CL1_0396 e423499397ab93d4ce084cb47a4c9143 272 SUPERFAMILY SSF142535 1 270 6.28E-87 T 30-10-2018 CL1_0396 e423499397ab93d4ce084cb47a4c9143 272 Gene3D G3DSA:3.40.630.50 1 186 2.3E-69 T 30-10-2018 CL1_0396 e423499397ab93d4ce084cb47a4c9143 272 Gene3D G3DSA:3.40.50.10700 187 272 3.9E-32 T 30-10-2018 CL1_1465 91528f4dc97ebde7ccd6270f1743787e 135 SUPERFAMILY SSF143870 11 127 4.32E-23 T 30-10-2018 IPR036504 CGI121/TPRKB superfamily Reactome: R-HSA-6782315 CL1_1465 91528f4dc97ebde7ccd6270f1743787e 135 Pfam PF08617 Kinase binding protein CGI-121 38 104 2.9E-5 T 30-10-2018 IPR013926 CGI121/TPRKB Reactome: R-HSA-6782315 CL1_1465 91528f4dc97ebde7ccd6270f1743787e 135 Gene3D G3DSA:3.30.2380.10 6 135 4.1E-44 T 30-10-2018 IPR036504 CGI121/TPRKB superfamily Reactome: R-HSA-6782315 CL1_1840 4cf32876a80376c5b0ab3eb92db63284 115 Gene3D G3DSA:2.60.40.730 1 115 8.2E-52 T 30-10-2018 IPR036073 Desulfoferrodoxin, ferrous iron-binding domain superfamily GO:0005506|GO:0016491|GO:0055114 CL1_1840 4cf32876a80376c5b0ab3eb92db63284 115 TIGRFAM TIGR00332 neela_ferrous: desulfoferrodoxin ferrous iron-binding domain 8 114 5.0E-34 T 30-10-2018 IPR002742 Desulfoferrodoxin, ferrous iron-binding domain GO:0005506|GO:0016491|GO:0055114 CL1_1840 4cf32876a80376c5b0ab3eb92db63284 115 SUPERFAMILY SSF49367 5 114 1.28E-40 T 30-10-2018 IPR036073 Desulfoferrodoxin, ferrous iron-binding domain superfamily GO:0005506|GO:0016491|GO:0055114 CL1_1840 4cf32876a80376c5b0ab3eb92db63284 115 Pfam PF01880 Desulfoferrodoxin 9 111 6.7E-33 T 30-10-2018 IPR002742 Desulfoferrodoxin, ferrous iron-binding domain GO:0005506|GO:0016491|GO:0055114 CL1_1158 afb1ac6d9636ccb7c7e642fc41523759 403 Pfam PF01384 Phosphate transporter family 19 392 2.7E-111 T 30-10-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 CL1_1195 1869c99d38ad1aa3df946d8ef6640d76 514 Pfam PF03553 Na+/H+ antiporter family 118 469 2.7E-67 T 30-10-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 CL1_1625 3abb4a0f0a06288cf6b0f4d59151fde3 126 Pfam PF09868 Uncharacterized protein conserved in archaea (DUF2095) 5 125 3.5E-66 T 30-10-2018 IPR018662 Protein of unknown function DUF2095 CL1_1952 65d339da9112fa38850238f21cd8f276 242 TIGRFAM TIGR01877 cas_cas6: CRISPR-associated endoribonuclease Cas6 39 236 7.5E-28 T 30-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 CL1_1952 65d339da9112fa38850238f21cd8f276 242 Gene3D G3DSA:3.30.70.1900 110 237 5.7E-7 T 30-10-2018 CL1_1952 65d339da9112fa38850238f21cd8f276 242 Gene3D G3DSA:3.30.70.1890 1 109 1.3E-7 T 30-10-2018 CL1_1952 65d339da9112fa38850238f21cd8f276 242 Pfam PF01881 CRISPR associated protein Cas6 84 236 9.3E-16 T 30-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 CL1_1847 2c8f92f72bbed7e6654c7605224f1ddd 187 Pfam PF06197 Protein of unknown function (DUF998) 12 172 2.2E-26 T 30-10-2018 IPR009339 Protein of unknown function DUF998 CL1_1499 bc474be1012a0b596b61392cc06a47c6 128 Gene3D G3DSA:2.40.50.140 64 128 6.4E-19 T 30-10-2018 CL1_1499 bc474be1012a0b596b61392cc06a47c6 128 Pfam PF01957 NfeD-like C-terminal, partner-binding 17 127 5.8E-16 T 30-10-2018 IPR002810 NfeD-like, C-terminal domain CL1_1499 bc474be1012a0b596b61392cc06a47c6 128 SUPERFAMILY SSF141322 63 126 7.45E-12 T 30-10-2018 CL1_1909 8cdc5eafaeb7711b9812d58016725a0f 459 SUPERFAMILY SSF52540 3 241 2.25E-31 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_1909 8cdc5eafaeb7711b9812d58016725a0f 459 Gene3D G3DSA:1.10.10.10 239 308 4.8E-6 T 30-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CL1_1909 8cdc5eafaeb7711b9812d58016725a0f 459 Pfam PF03008 Archaea bacterial proteins of unknown function 307 404 1.7E-28 T 30-10-2018 IPR004256 Domain of unknown function DUF234, DEXX-box ATPase C-terminal CL1_1909 8cdc5eafaeb7711b9812d58016725a0f 459 Pfam PF01637 ATPase domain predominantly from Archaea 5 182 2.6E-14 T 30-10-2018 IPR011579 ATPase domain GO:0005524 CL1_1909 8cdc5eafaeb7711b9812d58016725a0f 459 SUPERFAMILY SSF46785 241 299 9.26E-6 T 30-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CL1_1909 8cdc5eafaeb7711b9812d58016725a0f 459 Gene3D G3DSA:3.40.50.300 3 169 4.9E-25 T 30-10-2018 CL1_0301 d50eaf5b88234b46220b6c993e64580e 514 SUPERFAMILY SSF49464 246 297 2.71E-6 T 30-10-2018 IPR008969 Carboxypeptidase-like, regulatory domain superfamily CL1_0203 178ea9a5fc7ab75408ee949441fd03bf 197 Pfam PF06195 Protein of unknown function (DUF996) 38 172 1.7E-19 T 30-10-2018 IPR010397 Protein of unknown function DUF996 CL1_1576 113fa7d3546de5092955af2654bcca48 205 SUPERFAMILY SSF52402 6 153 2.87E-21 T 30-10-2018 CL1_1576 113fa7d3546de5092955af2654bcca48 205 Gene3D G3DSA:3.40.50.620 2 200 6.1E-62 T 30-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CL1_1723 fa98146aca2720822104ed6bdf7a72f1 248 SMART SM00331 6 248 1.4E-30 T 30-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CL1_1723 fa98146aca2720822104ed6bdf7a72f1 248 SUPERFAMILY SSF81606 16 246 1.31E-57 T 30-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CL1_1723 fa98146aca2720822104ed6bdf7a72f1 248 SMART SM00332 9 246 7.2E-35 T 30-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CL1_1723 fa98146aca2720822104ed6bdf7a72f1 248 Gene3D G3DSA:3.60.40.10 10 248 1.2E-65 T 30-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CL1_1723 fa98146aca2720822104ed6bdf7a72f1 248 Pfam PF13672 Protein phosphatase 2C 19 208 4.9E-16 T 30-10-2018 CL1_1479 0d690cbe8279421e2e46d23bec66be18 487 PIRSF PIRSF018875 1 487 1.7E-81 T 30-10-2018 IPR018646 Membrane protein of 12 TMs CL1_1479 0d690cbe8279421e2e46d23bec66be18 487 Pfam PF09847 Membrane protein of 12 TMs 40 480 9.2E-82 T 30-10-2018 IPR018646 Membrane protein of 12 TMs CL1_0675 3b5c020ce635db7ed51c8cb7ca6f49d3 215 TIGRFAM TIGR04288 CGP_CTERM: CGP-CTERM domain 190 207 8.3E-5 T 30-10-2018 IPR027552 CGP-CTERM domain CL1_1430 667ee61708d075e3775f22ba454f4f30 133 Pfam PF04039 Domain related to MnhB subunit of Na+/H+ antiporter 6 120 1.9E-26 T 30-10-2018 IPR007182 Na+/H+ antiporter MnhB subunit-related protein CL1_1794 09ff5874fb8d1fcb933e4a1bd003716e 550 Pfam PF10102 Domain of unknown function (DUF2341) 205 286 2.5E-18 T 30-10-2018 IPR018765 Domain of unknown function DUF2341 CL1_0023 7af150d6e5f4ae33c5ad7c95a5a833ec 350 Pfam PF02653 Branched-chain amino acid transport system / permease component 60 331 1.5E-38 T 30-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 CL1_1135 488f02477391ad09ec15b3a88f250c49 515 Pfam PF00361 Proton-conducting membrane transporter 138 438 7.6E-64 T 30-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CL1_1135 488f02477391ad09ec15b3a88f250c49 515 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 77 124 1.2E-11 T 30-10-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CL1_1135 488f02477391ad09ec15b3a88f250c49 515 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 226 247 3.0E-15 T 30-10-2018 CL1_1135 488f02477391ad09ec15b3a88f250c49 515 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 86 111 3.0E-15 T 30-10-2018 CL1_1135 488f02477391ad09ec15b3a88f250c49 515 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 321 333 3.0E-15 T 30-10-2018 CL1_1135 488f02477391ad09ec15b3a88f250c49 515 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 114 134 3.0E-15 T 30-10-2018 CL1_1662 530f280a8139db4236a342ac351d1125 182 Pfam PF06197 Protein of unknown function (DUF998) 15 174 6.8E-12 T 30-10-2018 IPR009339 Protein of unknown function DUF998 CL1_0577 de31b2c3d1df2aba556d58f756ae9ee3 79 SUPERFAMILY SSF54909 2 75 1.34E-16 T 30-10-2018 IPR011008 Dimeric alpha-beta barrel CL1_0577 de31b2c3d1df2aba556d58f756ae9ee3 79 Gene3D G3DSA:3.30.70.920 1 74 2.7E-22 T 30-10-2018 CL1_0577 de31b2c3d1df2aba556d58f756ae9ee3 79 Pfam PF01037 Lrp/AsnC ligand binding domain 6 74 1.2E-16 T 30-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CL1_1066 e03f550101327b629f459c0181d80bfd 184 Gene3D G3DSA:1.20.120.330 18 132 3.6E-8 T 30-10-2018 CL1_0504 39a196bcc4a5aa842a7bdf9952f98dcf 220 SUPERFAMILY SSF159071 44 102 3.4E-5 T 30-10-2018 CL1_0868 235b73cb6fa3d035bb8ac4d01ee8e274 575 SUPERFAMILY SSF88713 5 244 3.34E-15 T 30-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CL1_1655 a0f81bdedc305abcf1c4fd9bc5f0aa3e 292 Pfam PF01751 Toprim domain 8 88 1.9E-7 T 30-10-2018 IPR006171 TOPRIM domain CL1_1655 a0f81bdedc305abcf1c4fd9bc5f0aa3e 292 Gene3D G3DSA:3.40.1360.10 4 114 4.3E-6 T 30-10-2018 CL1_1655 a0f81bdedc305abcf1c4fd9bc5f0aa3e 292 SMART SM00493 5 84 9.8E-7 T 30-10-2018 IPR006171 TOPRIM domain CL1_1088 7e664fdfb8711f3389d36cf9bd5261a0 260 Pfam PF05763 Protein of unknown function (DUF835) 126 246 2.5E-31 T 30-10-2018 IPR008553 Domain of unknown function DUF835 CL1_1075 7475a42f6f0256af540b3b6f4856bf31 517 SUPERFAMILY SSF56281 1 514 3.14E-38 T 30-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like CL1_1075 7475a42f6f0256af540b3b6f4856bf31 517 Pfam PF00753 Metallo-beta-lactamase superfamily 83 259 1.1E-4 T 30-10-2018 IPR001279 Metallo-beta-lactamase CL1_1060 bee2007ea4503141113f1c8e0ac7c422 1299 PIRSF PIRSF016275 3 1213 0.0 T 30-10-2018 IPR004475 DNA polymerase II large subunit DP2 GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CL1_1060 bee2007ea4503141113f1c8e0ac7c422 1299 Hamap MF_00324 DNA polymerase II large subunit [polC]. 1 1227 521.205 T 30-10-2018 IPR004475 DNA polymerase II large subunit DP2 GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CL1_1060 bee2007ea4503141113f1c8e0ac7c422 1299 TIGRFAM TIGR00354 polC: DNA polymerase II, large subunit DP2 9 1205 0.0 T 30-10-2018 IPR004475 DNA polymerase II large subunit DP2 GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CL1_1060 bee2007ea4503141113f1c8e0ac7c422 1299 Pfam PF03833 DNA polymerase II large subunit DP2 13 962 0.0 T 30-10-2018 IPR016033 DNA polymerase II large subunit DP2, N-terminal KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CL1_1535 cea353395a110d047d540b72d38bbc59 188 Gene3D G3DSA:1.20.120.1760 7 188 6.8E-51 T 30-10-2018 CL1_1535 cea353395a110d047d540b72d38bbc59 188 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 68 90 - T 30-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CL1_1535 cea353395a110d047d540b72d38bbc59 188 Pfam PF01066 CDP-alcohol phosphatidyltransferase 26 90 5.2E-15 T 30-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CL1_0006 730dd9f710b51613821ba9f95e9a3789 97 SUPERFAMILY SSF46579 5 94 1.7E-6 T 30-10-2018 CL1_0006 730dd9f710b51613821ba9f95e9a3789 97 Gene3D G3DSA:1.10.287.370 1 97 1.5E-35 T 30-10-2018 IPR009053 Prefoldin CL1_0006 730dd9f710b51613821ba9f95e9a3789 97 Pfam PF01920 Prefoldin subunit 10 94 5.7E-7 T 30-10-2018 IPR002777 Prefoldin beta-like GO:0006457|GO:0016272|GO:0051082 Reactome: R-HSA-389957 CL1_1447 8e7db0eccfea3ca870080aa793c9bea0 333 SUPERFAMILY SSF161098 96 320 1.8E-18 T 30-10-2018 IPR035906 MetI-like superfamily CL1_1447 8e7db0eccfea3ca870080aa793c9bea0 333 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 116 333 2.0E-44 T 30-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 CL1_1447 8e7db0eccfea3ca870080aa793c9bea0 333 Gene3D G3DSA:1.10.3720.10 92 327 3.5E-25 T 30-10-2018 IPR035906 MetI-like superfamily CL1_1846 76639684e800d0dcc0d55776e44adcd6 180 Pfam PF00881 Nitroreductase family 63 150 1.4E-12 T 30-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 CL1_1846 76639684e800d0dcc0d55776e44adcd6 180 Pfam PF00881 Nitroreductase family 7 62 8.1E-17 T 30-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 CL1_1846 76639684e800d0dcc0d55776e44adcd6 180 SUPERFAMILY SSF55469 1 175 1.05E-49 T 30-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CL1_1846 76639684e800d0dcc0d55776e44adcd6 180 Gene3D G3DSA:3.40.109.10 1 173 3.0E-51 T 30-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CL1_0990 f6e3cd6f68ea7795db06a874cef9a924 511 Pfam PF01943 Polysaccharide biosynthesis protein 12 279 3.0E-22 T 30-10-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 CL1_0990 f6e3cd6f68ea7795db06a874cef9a924 511 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 342 476 6.9E-22 T 30-10-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain CL1_0391 9ed419666190145afb5143ffd1232934 402 SUPERFAMILY SSF53743 1 281 1.31E-38 T 30-10-2018 IPR009015 L-fucose isomerase, N-terminal/central domain superfamily GO:0005737|GO:0005996|GO:0016861 CL1_0687 26274d39e33126c4ffbfd23b6aeb174c 96 Gene3D G3DSA:1.10.10.10 1 94 1.5E-25 T 30-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CL1_0687 26274d39e33126c4ffbfd23b6aeb174c 96 Pfam PF03551 Transcriptional regulator PadR-like family 11 80 5.1E-20 T 30-10-2018 IPR005149 Transcription regulator PadR, N-terminal CL1_0687 26274d39e33126c4ffbfd23b6aeb174c 96 SUPERFAMILY SSF46785 2 92 1.7E-26 T 30-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CL1_1189 c3172845eb352f6708e213393b13c6ab 115 Pfam PF03788 LrgA family 15 106 2.9E-28 T 30-10-2018 IPR005538 LrgA/CidA family GO:0016021 CL1_1176 adc1e28e57f96fc782cde2c42f7be748 286 Pfam PF08241 Methyltransferase domain 131 234 4.9E-10 T 30-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 CL1_1176 adc1e28e57f96fc782cde2c42f7be748 286 Gene3D G3DSA:3.40.50.150 98 276 2.3E-26 T 30-10-2018 CL1_1176 adc1e28e57f96fc782cde2c42f7be748 286 SUPERFAMILY SSF53335 82 262 8.15E-36 T 30-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CL1_0999 dd5f1861ef27971f45aa1d6d91c0f893 323 PIRSF PIRSF004976 1 317 1.6E-111 T 30-10-2018 IPR035107 tRNA thiolation protein, TtcA/Ctu1 type GO:0008033 Reactome: R-HSA-6782315 CL1_0999 dd5f1861ef27971f45aa1d6d91c0f893 323 Gene3D G3DSA:3.40.50.620 1 318 5.0E-87 T 30-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CL1_0999 dd5f1861ef27971f45aa1d6d91c0f893 323 SUPERFAMILY SSF52402 36 270 1.83E-54 T 30-10-2018 CL1_0999 dd5f1861ef27971f45aa1d6d91c0f893 323 TIGRFAM TIGR00269 TIGR00269: TIGR00269 family protein 204 305 4.7E-37 T 30-10-2018 IPR000541 Cytoplasmic tRNA 2-thiolation protein 1 GO:0000049|GO:0002098|GO:0034227 Reactome: R-HSA-6782315 CL1_0999 dd5f1861ef27971f45aa1d6d91c0f893 323 Pfam PF01171 PP-loop family 50 228 3.4E-14 T 30-10-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 CL1_0506 77f9fd5cf26f9791ac067cdb924e4c52 371 Pfam PF01901 Putative O-antigen polymerase 53 328 2.0E-16 T 30-10-2018 IPR002760 Putative O-antigen polymerase CL1_0215 b045018647944e0bb5bdeb9af88fd817 85 Gene3D G3DSA:1.20.1280.290 1 84 3.9E-10 T 30-10-2018 CL1_0209 2d18ade5865659013935a08fedf8e795 270 SUPERFAMILY SSF100950 12 120 8.48E-7 T 30-10-2018 IPR037171 NagB/RpiA transferase-like CL1_0942 136cbf030316ef21feb3584bb0d01a45 175 TIGRFAM TIGR03879 near_KaiC_dom: probable regulatory domain 30 102 6.6E-26 T 30-10-2018 IPR022285 Conserved hypothetical protein CHP03879, regulatory domain, putative CL1_0942 136cbf030316ef21feb3584bb0d01a45 175 Gene3D G3DSA:1.10.10.60 56 84 6.6E-6 T 30-10-2018 CL1_0942 136cbf030316ef21feb3584bb0d01a45 175 SUPERFAMILY SSF46785 60 174 1.03E-5 T 30-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CL1_1480 8b4b788d6e99a55b71adbdb970d26342 118 Gene3D G3DSA:3.40.1230.10 1 118 4.9E-36 T 30-10-2018 IPR036748 MTH938-like superfamily CL1_1480 8b4b788d6e99a55b71adbdb970d26342 118 SUPERFAMILY SSF64076 2 118 5.63E-35 T 30-10-2018 IPR036748 MTH938-like superfamily CL1_1480 8b4b788d6e99a55b71adbdb970d26342 118 Pfam PF04430 Protein of unknown function (DUF498/DUF598) 8 108 6.0E-12 T 30-10-2018 IPR007523 NDUFAF3/Mth938 domain-containing protein CL1_0740 431fc786cee097868243ed002eec2428 119 SUPERFAMILY SSF46785 15 114 4.15E-24 T 30-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CL1_0740 431fc786cee097868243ed002eec2428 119 Pfam PF03551 Transcriptional regulator PadR-like family 26 99 2.4E-23 T 30-10-2018 IPR005149 Transcription regulator PadR, N-terminal CL1_0740 431fc786cee097868243ed002eec2428 119 Gene3D G3DSA:1.10.10.10 3 119 1.1E-28 T 30-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CL1_0182 fdbfaca00d66db0779c99bd8c317d0c8 375 Pfam PF04007 Protein of unknown function (DUF354) 1 335 3.4E-100 T 30-10-2018 IPR007152 Protein of unknown function DUF354 CL1_0182 fdbfaca00d66db0779c99bd8c317d0c8 375 SUPERFAMILY SSF53756 1 321 1.26E-22 T 30-10-2018 CL1_0182 fdbfaca00d66db0779c99bd8c317d0c8 375 PIRSF PIRSF005357 1 346 5.5E-117 T 30-10-2018 IPR007152 Protein of unknown function DUF354 CL1_1636 feab1f2bf8110a02ab3ad78bf2229650 202 SUPERFAMILY SSF81301 90 174 4.73E-15 T 30-10-2018 CL1_1636 feab1f2bf8110a02ab3ad78bf2229650 202 Gene3D G3DSA:1.10.10.10 1 78 1.7E-5 T 30-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CL1_1636 feab1f2bf8110a02ab3ad78bf2229650 202 Gene3D G3DSA:3.30.460.10 79 156 4.6E-10 T 30-10-2018 CL1_1636 feab1f2bf8110a02ab3ad78bf2229650 202 SUPERFAMILY SSF46785 5 76 5.16E-5 T 30-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CL1_1636 feab1f2bf8110a02ab3ad78bf2229650 202 Pfam PF01909 Nucleotidyltransferase domain 81 149 6.2E-9 T 30-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 CL1_0582 a6894fe803ed7687a303b0ac2d615934 253 SUPERFAMILY SSF56300 1 252 2.31E-56 T 30-10-2018 CL1_0582 a6894fe803ed7687a303b0ac2d615934 253 PIRSF PIRSF000883 2 253 1.1E-27 T 30-10-2018 IPR011152 Phosphoesterase MJ0912 CL1_0582 a6894fe803ed7687a303b0ac2d615934 253 Gene3D G3DSA:3.60.21.10 1 253 1.3E-50 T 30-10-2018 IPR029052 Metallo-dependent phosphatase-like CL1_1006 2ec8bbe12940e99ebf2a598737457f65 670 Pfam PF04312 Protein of unknown function (DUF460) 212 352 4.4E-49 T 30-10-2018 IPR007408 Protein of unknown function DUF460 CL1_0063 c2aa9d37b6610528c0067019ae6e94fd 328 Pfam PF12773 Double zinc ribbon 283 324 2.6E-10 T 30-10-2018 IPR025874 Double zinc ribbon CL1_0063 c2aa9d37b6610528c0067019ae6e94fd 328 SUPERFAMILY SSF117892 75 203 4.84E-13 T 30-10-2018 IPR036013 Band 7/SPFH domain superfamily CL1_0063 c2aa9d37b6610528c0067019ae6e94fd 328 Pfam PF13421 SPFH domain-Band 7 family 16 204 1.0E-35 T 30-10-2018 IPR033880 SPFH domain, YdjI-like CL1_0071 96296555a64d15841d3eccf612ca9b8f 110 Pfam PF01934 Protein of unknown function DUF86 12 104 1.1E-27 T 30-10-2018 IPR008201 Protein of unknown function DUF86 CL1_1115 8446341f40150c88ce1065e130ee22b5 276 SUPERFAMILY SSF102114 13 239 2.88E-29 T 30-10-2018 CL1_1115 8446341f40150c88ce1065e130ee22b5 276 Gene3D G3DSA:3.20.20.70 6 222 1.2E-19 T 30-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CL1_1115 8446341f40150c88ce1065e130ee22b5 276 SMART SM00729 14 217 5.7E-4 T 30-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 CL1_1115 8446341f40150c88ce1065e130ee22b5 276 Pfam PF04055 Radical SAM superfamily 21 160 1.7E-8 T 30-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CL1_0851 ff787cfe7b693fba9dfff27a63e6d717 334 PIRSF PIRSF018671 6 334 9.9E-118 T 30-10-2018 IPR014495 Uncharacterised conserved protein UCP018671 CL1_0851 ff787cfe7b693fba9dfff27a63e6d717 334 Pfam PF07760 Protein of unknown function (DUF1616) 17 317 5.5E-94 T 30-10-2018 IPR011674 Domain of unknown function DUF1616 CL1_0979 ffaf4d89cddd0dab8fb718b1c441cb63 454 Pfam PF03008 Archaea bacterial proteins of unknown function 307 397 3.3E-28 T 30-10-2018 IPR004256 Domain of unknown function DUF234, DEXX-box ATPase C-terminal CL1_0979 ffaf4d89cddd0dab8fb718b1c441cb63 454 Pfam PF01637 ATPase domain predominantly from Archaea 5 199 1.5E-20 T 30-10-2018 IPR011579 ATPase domain GO:0005524 CL1_0979 ffaf4d89cddd0dab8fb718b1c441cb63 454 SUPERFAMILY SSF46785 217 352 1.51E-9 T 30-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CL1_0979 ffaf4d89cddd0dab8fb718b1c441cb63 454 Gene3D G3DSA:3.40.50.300 3 165 2.0E-29 T 30-10-2018 CL1_0979 ffaf4d89cddd0dab8fb718b1c441cb63 454 SUPERFAMILY SSF52540 4 239 2.24E-35 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_0979 ffaf4d89cddd0dab8fb718b1c441cb63 454 Pfam PF01022 Bacterial regulatory protein, arsR family 240 281 1.6E-4 T 30-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CL1_1456 fd98befebabb6e1bf0f35a3b5e2db514 421 Gene3D G3DSA:3.40.1710.10 35 196 9.6E-33 T 30-10-2018 CL1_1456 fd98befebabb6e1bf0f35a3b5e2db514 421 Pfam PF12698 ABC-2 family transporter protein 13 396 3.0E-31 T 30-10-2018 CL1_1250 d9d3dcc82b8d68cfe3397aab29fd9595 320 Pfam PF01384 Phosphate transporter family 19 307 1.4E-70 T 30-10-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 CL1_0881 f1b6fcbeb9e5c9e2e75cc9380ac89720 120 Gene3D G3DSA:3.30.70.3250 1 120 2.6E-50 T 30-10-2018 IPR038085 Rnp2-like domain superfamily Reactome: R-HSA-6784531 CL1_0881 f1b6fcbeb9e5c9e2e75cc9380ac89720 120 Hamap MF_00755 Ribonuclease P protein component 2 [rnp2]. 5 116 26.984 T 30-10-2018 IPR002759 Ribonuclease P/MRP protein subunit GO:0004540|GO:0008033 Reactome: R-HSA-6784531 CL1_0881 f1b6fcbeb9e5c9e2e75cc9380ac89720 120 SUPERFAMILY SSF160350 4 116 2.09E-35 T 30-10-2018 IPR038085 Rnp2-like domain superfamily Reactome: R-HSA-6784531 CL1_0881 f1b6fcbeb9e5c9e2e75cc9380ac89720 120 Pfam PF01900 Rpp14/Pop5 family 17 113 1.5E-23 T 30-10-2018 IPR002759 Ribonuclease P/MRP protein subunit GO:0004540|GO:0008033 Reactome: R-HSA-6784531 CL1_0881 f1b6fcbeb9e5c9e2e75cc9380ac89720 120 PIRSF PIRSF004952 4 120 3.0E-47 T 30-10-2018 IPR016434 Ribonuclease P, protein component 2 GO:0001682|GO:0004526 CL1_0364 ff9bd014b1c95769ec1214c55e8fd013 251 SUPERFAMILY SSF55307 159 246 8.93E-12 T 30-10-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 CL1_0364 ff9bd014b1c95769ec1214c55e8fd013 251 Gene3D G3DSA:3.40.50.1440 115 249 2.8E-8 T 30-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 CL1_1937 32e3114b1919498f50618ae8fd62c106 213 TIGRFAM TIGR00372 cas4: CRISPR-associated protein Cas4 15 210 7.8E-29 T 30-10-2018 IPR013343 CRISPR-associated protein Cas4 CL1_1937 32e3114b1919498f50618ae8fd62c106 213 Gene3D G3DSA:3.90.320.10 3 211 4.2E-23 T 30-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal CL1_1937 32e3114b1919498f50618ae8fd62c106 213 Pfam PF12705 PD-(D/E)XK nuclease superfamily 55 208 2.6E-6 T 30-10-2018 IPR038726 PD-(D/E)XK endonuclease-like domain, AddAB-type CL1_0464 f2c75f3a3e05acc49677aeabfbd0ccea 219 Pfam PF02361 Cobalt transport protein 24 193 6.1E-25 T 30-10-2018 IPR003339 ABC/ECF transporter, transmembrane component CL1_0233 479a0383f4de84c20877ef789ae3fbbb 110 Pfam PF11419 Protein of unknown function (DUF3194) 15 97 3.6E-27 T 30-10-2018 IPR024502 Protein of unknown function DUF3194 CL1_0233 479a0383f4de84c20877ef789ae3fbbb 110 Gene3D G3DSA:3.30.300.100 1 110 2.8E-43 T 30-10-2018 IPR035954 MTH677-like superfamily CL1_0233 479a0383f4de84c20877ef789ae3fbbb 110 SUPERFAMILY SSF110783 14 99 9.68E-6 T 30-10-2018 IPR035954 MTH677-like superfamily CL1_1735 401aaf1d0581dca225a2b80df0711598 402 Gene3D G3DSA:3.40.50.300 28 145 1.9E-5 T 30-10-2018 CL1_1735 401aaf1d0581dca225a2b80df0711598 402 SUPERFAMILY SSF52540 41 223 6.9E-16 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_1735 401aaf1d0581dca225a2b80df0711598 402 Pfam PF13173 AAA domain 44 177 1.6E-17 T 30-10-2018 CL1_0031 4af5322e19024cf7876198aff736528f 200 Pfam PF02517 CAAX protease self-immunity 112 188 2.8E-7 T 30-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 CL1_1149 f646f9a3620d192518b076165be1bd23 276 Pfam PF04422 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term 15 91 2.0E-18 T 30-10-2018 IPR007516 Coenzyme F420 hydrogenase/dehydrogenase beta subunit, N-terminal CL1_1149 f646f9a3620d192518b076165be1bd23 276 Pfam PF04432 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus 101 249 7.5E-29 T 30-10-2018 IPR007525 Coenzyme F420 hydrogenase/dehydrogenase beta subunit, C-terminal CL1_0603 b970bc982dc70d313ffa139bb9adab45 196 Hamap MF_00234 Adenylate kinase [adkA]. 3 189 44.977 T 30-10-2018 IPR023477 Adenylate kinase AdkA GO:0004017 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 CL1_0603 b970bc982dc70d313ffa139bb9adab45 196 SUPERFAMILY SSF52540 1 188 4.51E-21 T 30-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CL1_0603 b970bc982dc70d313ffa139bb9adab45 196 Pfam PF13207 AAA domain 8 145 8.5E-37 T 30-10-2018 CL1_0603 b970bc982dc70d313ffa139bb9adab45 196 Gene3D G3DSA:3.40.50.300 3 189 2.8E-57 T 30-10-2018 CL1_0279 d68ae08c600c783a964aec50fa92eb7e 184 SUPERFAMILY SSF47240 23 173 5.02E-21 T 30-10-2018 IPR009078 Ferritin-like superfamily CL1_0279 d68ae08c600c783a964aec50fa92eb7e 184 Gene3D G3DSA:1.20.1260.10 18 173 1.7E-27 T 30-10-2018 IPR012347 Ferritin-like CL1_0279 d68ae08c600c783a964aec50fa92eb7e 184 Pfam PF02915 Rubrerythrin 35 169 2.3E-11 T 30-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 CL1_0008 b4f453f7a9653b582cfe77e273e1942c 281 SUPERFAMILY SSF52518 19 260 1.35E-74 T 30-10-2018 IPR029061 Thiamin diphosphate-binding fold CL1_0008 b4f453f7a9653b582cfe77e273e1942c 281 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 56 202 8.0E-35 T 30-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CL1_0008 b4f453f7a9653b582cfe77e273e1942c 281 Gene3D G3DSA:3.40.50.970 86 244 9.9E-28 T 30-10-2018 CL1_1309 d7b6c0bf6cfbe264dc3a7ab43084f430 167 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 27 156 2.6E-35 T 30-10-2018 IPR006464 N-acetyltransferase RimI/Ard1 GO:0006474|GO:0016407 CL1_1309 d7b6c0bf6cfbe264dc3a7ab43084f430 167 SUPERFAMILY SSF55729 16 157 2.13E-39 T 30-10-2018 IPR016181 Acyl-CoA N-acyltransferase CL1_1309 d7b6c0bf6cfbe264dc3a7ab43084f430 167 Gene3D G3DSA:3.40.630.30 16 163 4.7E-49 T 30-10-2018 CL1_1309 d7b6c0bf6cfbe264dc3a7ab43084f430 167 Pfam PF00583 Acetyltransferase (GNAT) family 28 137 1.2E-29 T 30-10-2018 IPR000182 GNAT domain CL1_1737 699daec17e0b505e954a5942f0f9de06 317 Gene3D G3DSA:1.10.10.10 239 317 1.9E-11 T 30-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CL1_1737 699daec17e0b505e954a5942f0f9de06 317 SUPERFAMILY SSF46785 263 316 6.23E-13 T 30-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CL1_1737 699daec17e0b505e954a5942f0f9de06 317 Pfam PF12802 MarR family 265 306 1.2E-8 T 30-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CL1_0158 c6ccf3416d3957ecfec97fe12794918b 237 Pfam PF01940 Integral membrane protein DUF92 12 215 6.2E-50 T 30-10-2018 IPR002794 Protein of unknown function DUF92, TMEM19 GO:0016021 CL1_1336 0e7a456eb82b90b1a91334d3a8d9cbae 163 SUPERFAMILY SSF48452 21 95 8.43E-5 T 30-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 CL1_0864 b15e603e01e28ed7a56f4c4119b7a040 2092 Pfam PF03415 Clostripain family 703 1097 2.5E-48 T 30-10-2018 IPR005077 Peptidase C11, clostripain CL1_0864 b15e603e01e28ed7a56f4c4119b7a040 2092 ProSitePatterns PS00018 EF-hand calcium-binding domain. 852 864 - T 30-10-2018 IPR018247 EF-Hand 1, calcium-binding site CL1_0864 b15e603e01e28ed7a56f4c4119b7a040 2092 Gene3D G3DSA:2.60.40.10 1594 1685 1.3E-19 T 30-10-2018 IPR013783 Immunoglobulin-like fold CL1_0864 b15e603e01e28ed7a56f4c4119b7a040 2092 Gene3D G3DSA:2.60.40.10 1688 1785 3.3E-7 T 30-10-2018 IPR013783 Immunoglobulin-like fold CL1_0864 b15e603e01e28ed7a56f4c4119b7a040 2092 Gene3D G3DSA:2.60.40.10 1787 1887 4.7E-11 T 30-10-2018 IPR013783 Immunoglobulin-like fold CL1_0864 b15e603e01e28ed7a56f4c4119b7a040 2092 Gene3D G3DSA:2.60.40.10 1400 1492 3.2E-18 T 30-10-2018 IPR013783 Immunoglobulin-like fold CL1_0864 b15e603e01e28ed7a56f4c4119b7a040 2092 Gene3D G3DSA:2.60.40.10 1203 1297 1.3E-15 T 30-10-2018 IPR013783 Immunoglobulin-like fold CL1_0864 b15e603e01e28ed7a56f4c4119b7a040 2092 Gene3D G3DSA:2.60.40.10 1298 1398 2.1E-9 T 30-10-2018 IPR013783 Immunoglobulin-like fold CL1_0864 b15e603e01e28ed7a56f4c4119b7a040 2092 Gene3D G3DSA:2.60.40.10 1495 1593 7.3E-8 T 30-10-2018 IPR013783 Immunoglobulin-like fold CL1_0864 b15e603e01e28ed7a56f4c4119b7a040 2092 Gene3D G3DSA:3.40.50.11970 691 822 4.8E-10 T 30-10-2018 CL1_1112 a1249a7ccad55b802d25909bed3345e4 250 TIGRFAM TIGR04288 CGP_CTERM: CGP-CTERM domain 228 246 1.6E-8 T 30-10-2018 IPR027552 CGP-CTERM domain CL1_1190 96b299debb1202d0d56d205984e6fd2e 485 Gene3D G3DSA:2.130.10.10 11 264 7.2E-7 T 30-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 CL1_1190 96b299debb1202d0d56d205984e6fd2e 485 Pfam PF09910 Uncharacterized protein conserved in archaea (DUF2139) 31 359 4.5E-149 T 30-10-2018 IPR016675 Uncharacterised conserved protein UCP016666 CL1_1190 96b299debb1202d0d56d205984e6fd2e 485 PIRSF PIRSF016666 1 485 4.1E-239 T 30-10-2018 IPR016675 Uncharacterised conserved protein UCP016666 CL1_1190 96b299debb1202d0d56d205984e6fd2e 485 SUPERFAMILY SSF50998 18 214 2.43E-8 T 30-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily CL1_1130 71857f34e84183466c2b5dd8c95ba6d0 330 Pfam PF00146 NADH dehydrogenase 17 324 1.5E-58 T 30-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CL1_0176 69d3d87d0b5219929e11ba064bc1c1c2 187 Gene3D G3DSA:1.25.10.10 7 160 1.2E-10 T 30-10-2018 IPR011989 Armadillo-like helical CL1_0176 69d3d87d0b5219929e11ba064bc1c1c2 187 SUPERFAMILY SSF48371 30 155 1.52E-13 T 30-10-2018 IPR016024 Armadillo-type fold CL1_1599 42528f2d16d473e5f8d392b84017da26 338 Pfam PF13439 Glycosyltransferase Family 4 10 164 1.6E-31 T 30-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 CL1_1599 42528f2d16d473e5f8d392b84017da26 338 Gene3D G3DSA:3.40.50.2000 1 167 1.2E-37 T 30-10-2018 CL1_1599 42528f2d16d473e5f8d392b84017da26 338 Gene3D G3DSA:3.40.50.2000 168 312 1.5E-32 T 30-10-2018 CL1_1599 42528f2d16d473e5f8d392b84017da26 338 Pfam PF13692 Glycosyl transferases group 1 175 302 2.2E-24 T 30-10-2018 CL1_1599 42528f2d16d473e5f8d392b84017da26 338 SUPERFAMILY SSF53756 3 337 1.08E-77 T 30-10-2018 CL1_0936 54a6f587802e39f39327367cd0bb1108 103 SUPERFAMILY SSF81573 35 89 2.35E-6 T 30-10-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain superfamily CL1_0936 54a6f587802e39f39327367cd0bb1108 103 TIGRFAM TIGR02926 AhaH: ATP synthase archaeal, H subunit 5 88 6.1E-16 T 30-10-2018 IPR014275 ATPase, A1A0, subunit H CL1_0936 54a6f587802e39f39327367cd0bb1108 103 Gene3D G3DSA:1.20.5.620 32 91 2.4E-6 T 30-10-2018 CL1_1374 e1137416ed15391b3f31efda24e6be95 282 Gene3D G3DSA:1.10.357.140 12 151 3.8E-10 T 30-10-2018 CL1_1374 e1137416ed15391b3f31efda24e6be95 282 Pfam PF01040 UbiA prenyltransferase family 19 269 4.6E-33 T 30-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 CL1_1090 1984263c12399c86e83bd06ba9d9ef20 360 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 12 321 1.0E-54 T 30-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD CL1_1090 1984263c12399c86e83bd06ba9d9ef20 360 TIGRFAM TIGR00374 TIGR00374: TIGR00374 family protein 13 323 4.5E-53 T 30-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD CL1_0170 23cea1f7d9661187db5bacf2701b69e4 61 Pfam PF04021 Class III signal peptide 3 25 1.2E-8 T 30-10-2018 IPR007166 Class III signal peptide motif CL1_1633 bf55d7c25dad8c91081c50764a24c10b 286 Gene3D G3DSA:1.10.1670.10 219 276 1.1E-8 T 30-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 CL1_1633 bf55d7c25dad8c91081c50764a24c10b 286 SUPERFAMILY SSF48150 92 270 4.01E-35 T 30-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CL1_1633 bf55d7c25dad8c91081c50764a24c10b 286 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 109 245 1.7E-11 T 30-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CL1_1633 bf55d7c25dad8c91081c50764a24c10b 286 Gene3D G3DSA:1.10.340.30 101 218 1.2E-23 T 30-10-2018 CL1_1633 bf55d7c25dad8c91081c50764a24c10b 286 SMART SM00478 113 271 3.2E-20 T 30-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CL1_0994 0eba5f158b36c216dfda6cb7c24c844a 238 SUPERFAMILY SSF53649 64 212 1.44E-5 T 30-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 CL1_0831 9a50cc4c551f4ed2d293504fc5d7b63e 405 Gene3D G3DSA:1.50.10.20 108 317 2.2E-5 T 30-10-2018 CL1_0831 9a50cc4c551f4ed2d293504fc5d7b63e 405 Gene3D G3DSA:1.50.10.20 318 398 1.8E-7 T 30-10-2018 CL1_0831 9a50cc4c551f4ed2d293504fc5d7b63e 405 SUPERFAMILY SSF48239 186 395 7.69E-15 T 30-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid CL1_1277 78e63990b3c2936c2d55b41c5ddaffb4 192 Pfam PF14470 Bacterial PH domain 13 105 1.9E-19 T 30-10-2018 IPR039519 YokE-like, PH domain CL1_1277 78e63990b3c2936c2d55b41c5ddaffb4 192 Pfam PF09851 Short C-terminal domain 162 189 2.9E-11 T 30-10-2018 IPR018649 SHOCT domain CL1_0570 bf82993af7feecf39e63c05af86d3583 293 Hamap MF_00055 MEMO1 family protein . 3 292 60.026 T 30-10-2018 IPR002737 MEMO1 family Reactome: R-HSA-6785631 CL1_0570 bf82993af7feecf39e63c05af86d3583 293 TIGRFAM TIGR04336 AmmeMemoSam_B: AmmeMemoRadiSam system protein B 5 290 1.5E-89 T 30-10-2018 CL1_0570 bf82993af7feecf39e63c05af86d3583 293 Gene3D G3DSA:3.40.830.10 3 293 3.3E-68 T 30-10-2018 CL1_0570 bf82993af7feecf39e63c05af86d3583 293 SUPERFAMILY SSF53213 57 252 1.67E-8 T 30-10-2018 CL1_0570 bf82993af7feecf39e63c05af86d3583 293 Pfam PF01875 Memo-like protein 7 290 8.5E-74 T 30-10-2018 IPR002737 MEMO1 family Reactome: R-HSA-6785631 CL1_0217 4668747c7b27fb5386002e4cc222b2fa 140 PIRSF PIRSF018748 1 140 1.1E-53 T 30-10-2018 IPR019271 Protein of unknown function DUF2284, metal-binding CL1_0217 4668747c7b27fb5386002e4cc222b2fa 140 Pfam PF10050 Predicted metal-binding protein (DUF2284) 2 125 4.5E-31 T 30-10-2018 IPR019271 Protein of unknown function DUF2284, metal-binding CL1_1959 c0c4eebd4a97708dea5999b35cbba889 101 TIGRFAM TIGR02579 cas_csx3: CRISPR-associated protein, Csx3 family 12 92 6.5E-36 T 30-10-2018 IPR013409 CRISPR-associated protein Csx3 CL1_1959 c0c4eebd4a97708dea5999b35cbba889 101 Pfam PF09620 CRISPR-associated protein (Cas_csx3) 17 91 8.0E-31 T 30-10-2018 IPR013409 CRISPR-associated protein Csx3 CL1_1174 8fa5d9ec4f492802eae187fca6739892 440 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 8 415 2.7E-50 T 30-10-2018 IPR002823 Protein of unknown function DUF112, transmembrane CL1_1316 bdc35903d2f64c9faada8c4a5842829b 279 Pfam PF05763 Protein of unknown function (DUF835) 98 231 3.2E-32 T 30-10-2018 IPR008553 Domain of unknown function DUF835 CL1_1870 3a57e2b2abe08250bce869f7c71b0005 398 Pfam PF03222 Tryptophan/tyrosine permease family 69 395 3.1E-26 T 30-10-2018 IPR018227 Amino acid/polyamine transporter 2 GO:0003333 CL1_0474 a3c41fb17aef66f7420f10622d221603 233 Pfam PF01963 TraB family 9 222 1.0E-14 T 30-10-2018 IPR002816 Pheromone shutdown, TraB CL1_0728 304eba14eb80658329645144fd5b76b8 225 Pfam PF04256 Protein of unknown function (DUF434) 2 56 5.1E-25 T 30-10-2018 IPR007368 Protein of unknown function DUF434 CL1_0728 304eba14eb80658329645144fd5b76b8 225 ProDom PD019177 PF1672 MJ0935 ST1363 PH1730 UNCHARACTERIZED ARCHAEAL 2 54 9.0E-16 T 30-10-2018 IPR007368 Protein of unknown function DUF434 CL1_1409 be074ed78494c45dd0d51c84acb4478d 139 Pfam PF04009 Protein of unknown function (DUF356) 5 110 1.3E-33 T 30-10-2018 IPR007154 Protein of unknown function DUF356 CL1_1409 be074ed78494c45dd0d51c84acb4478d 139 PIRSF PIRSF006606 3 133 2.7E-44 T 30-10-2018 IPR007154 Protein of unknown function DUF356 CL1_0505 76725da4bf6d9bac8867cb71b9b87f71 328 Pfam PF01901 Putative O-antigen polymerase 3 311 2.2E-61 T 30-10-2018 IPR002760 Putative O-antigen polymerase CL1_1015 68f615d98795c4515d19c5607895dd2a 434 Pfam PF01882 Protein of unknown function DUF58 214 293 9.1E-22 T 30-10-2018 IPR002881 Domain of unknown function DUF58 CL1_1979 033096b15cb602c5857971fb0ba1f501 308 Pfam PF12679 ABC-2 family transporter protein 5 307 2.6E-57 T 30-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 CL1_0181 034345fd4d56f3c90f8884e37a994a32 187 Pfam PF01944 Stage II sporulation protein M 15 182 6.9E-33 T 30-10-2018 IPR002798 Stage II sporulation protein M-like CL1_1285 1cd1f2c78940ea21e1c708e1d44d8e19 262 SUPERFAMILY SSF81442 47 188 2.13E-5 T 30-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CL1_1520 4b2423f9a75c65ef1252d391dfafe124 418 Pfam PF01882 Protein of unknown function DUF58 190 274 1.1E-22 T 30-10-2018 IPR002881 Domain of unknown function DUF58 CL1_0886 e66579e3fdd76e66452213eb2044b12c 299 SUPERFAMILY SSF161098 58 284 1.44E-49 T 30-10-2018 IPR035906 MetI-like superfamily CL1_0886 e66579e3fdd76e66452213eb2044b12c 299 SUPERFAMILY SSF160964 6 43 3.92E-7 T 30-10-2018 CL1_0886 e66579e3fdd76e66452213eb2044b12c 299 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 89 285 9.2E-17 T 30-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 CL1_0886 e66579e3fdd76e66452213eb2044b12c 299 Gene3D G3DSA:1.10.3720.10 54 296 5.4E-58 T 30-10-2018 IPR035906 MetI-like superfamily CL1_1062 661d5f4e4d7a4959c02fa417eeb41075 1279 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 734 740 - T 30-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CL1_1062 661d5f4e4d7a4959c02fa417eeb41075 1279 Pfam PF07669 Eco57I restriction-modification methylase 731 869 5.9E-11 T 30-10-2018 IPR011639 Restriction modification methylase Eco57I GO:0003677|GO:0003824|GO:0006304 CL1_1062 661d5f4e4d7a4959c02fa417eeb41075 1279 SUPERFAMILY SSF53335 260 888 3.52E-59 T 30-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CL1_1062 661d5f4e4d7a4959c02fa417eeb41075 1279 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 798 822 6.5E-16 T 30-10-2018 CL1_1062 661d5f4e4d7a4959c02fa417eeb41075 1279 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 445 461 6.5E-16 T 30-10-2018 CL1_1062 661d5f4e4d7a4959c02fa417eeb41075 1279 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 731 743 6.5E-16 T 30-10-2018 CL1_1062 661d5f4e4d7a4959c02fa417eeb41075 1279 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 510 524 6.5E-16 T 30-10-2018 CL1_0752 6cee6ea513e1c33002d80c490ff76fac 178 Pfam PF06510 Protein of unknown function (DUF1102) 38 176 1.0E-44 T 30-10-2018 IPR009482 Protein of unknown function DUF1102 CL1_1654 f6409aa6ec6f84bfba6384267c02a669 412 Gene3D G3DSA:3.90.550.10 48 267 8.6E-49 T 30-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases CL1_1654 f6409aa6ec6f84bfba6384267c02a669 412 Pfam PF13641 Glycosyltransferase like family 2 57 283 5.1E-40 T 30-10-2018 CL1_1654 f6409aa6ec6f84bfba6384267c02a669 412 SUPERFAMILY SSF53448 50 316 5.63E-61 T 30-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases CL1_0405 d6c4b4a55755f5da3ae43a244f90e878 156 Hamap MF_00146 dCTP deaminase [dcd]. 1 153 27.288 T 30-10-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 CL1_0405 d6c4b4a55755f5da3ae43a244f90e878 156 Gene3D G3DSA:2.70.40.10 1 156 1.0E-42 T 30-10-2018 IPR036157 dUTPase-like superfamily CL1_0405 d6c4b4a55755f5da3ae43a244f90e878 156 SUPERFAMILY SSF51283 1 153 3.66E-39 T 30-10-2018 IPR036157 dUTPase-like superfamily CL1_0405 d6c4b4a55755f5da3ae43a244f90e878 156 TIGRFAM TIGR02274 dCTP_deam: deoxycytidine triphosphate deaminase 9 152 2.1E-44 T 30-10-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 CL1_0405 d6c4b4a55755f5da3ae43a244f90e878 156 Pfam PF00692 dUTPase 49 139 1.6E-12 T 30-10-2018 IPR029054 dUTPase-like CL1_0716 6a2a5878a6f8f9aefb6080102567b088 266 SUPERFAMILY SSF50249 36 131 1.43E-10 T 30-10-2018 IPR012340 Nucleic acid-binding, OB-fold CL1_0716 6a2a5878a6f8f9aefb6080102567b088 266 Pfam PF01336 OB-fold nucleic acid binding domain 59 114 2.7E-8 T 30-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 CL1_0716 6a2a5878a6f8f9aefb6080102567b088 266 Gene3D G3DSA:2.40.50.140 19 141 5.5E-13 T 30-10-2018 CL1_0455 47c6c0da354d1e85cb3e0f8193702de9 59 SUPERFAMILY SSF46785 5 56 1.24E-12 T 30-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CL1_0455 47c6c0da354d1e85cb3e0f8193702de9 59 Gene3D G3DSA:1.10.10.10 3 56 9.5E-12 T 30-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CL1_0455 47c6c0da354d1e85cb3e0f8193702de9 59 Pfam PF08279 HTH domain 7 49 1.0E-4 T 30-10-2018 IPR013196 Helix-turn-helix, type 11 CL1_1838 b626d7ab1decaf647c795ebacfe65e2c 116 Pfam PF01883 Iron-sulfur cluster assembly protein 27 93 7.8E-11 T 30-10-2018 IPR002744 MIP18 family-like CL1_1838 b626d7ab1decaf647c795ebacfe65e2c 116 Gene3D G3DSA:3.30.300.130 24 108 6.8E-14 T 30-10-2018 IPR034904 Fe-S cluster assembly domain superfamily CL1_1838 b626d7ab1decaf647c795ebacfe65e2c 116 SUPERFAMILY SSF117916 26 89 7.19E-12 T 30-10-2018 IPR034904 Fe-S cluster assembly domain superfamily CL1_1343 f8f47d9e5438ef16b7405872d1d8283d 123 Pfam PF10066 Uncharacterized conserved protein (DUF2304) 4 107 2.0E-26 T 30-10-2018 IPR019277 Protein of unknown function DUF2304 CL1_1005 3274417aa4f557e495d0ade807d8b335 203 Pfam PF09997 Predicted membrane protein (DUF2238) 85 163 4.1E-6 T 30-10-2018 IPR014509 Uncharacterised conserved protein UCP020606 CL1_1600 9d881286b8434531efc215924ee0291b 401 Pfam PF04122 Putative cell wall binding repeat 2 106 173 4.3E-5 T 30-10-2018 IPR007253 Putative cell wall binding repeat 2 CL1_1301 12a509c0deaeb3f27e847dfec35eb5e8 263 SUPERFAMILY SSF53213 6 259 7.59E-26 T 30-10-2018 CL1_1301 12a509c0deaeb3f27e847dfec35eb5e8 263 Gene3D G3DSA:3.40.830.10 1 262 2.2E-71 T 30-10-2018 CL1_1301 12a509c0deaeb3f27e847dfec35eb5e8 263 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 7 253 1.7E-16 T 30-10-2018 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 CL1_1966 5ee1892261aa761332a5c28c2aade2f5 152 Gene3D G3DSA:3.40.50.1000 11 147 1.1E-8 T 30-10-2018 IPR023214 HAD superfamily CL1_1966 5ee1892261aa761332a5c28c2aade2f5 152 SUPERFAMILY SSF56784 15 133 1.02E-11 T 30-10-2018 IPR036412 HAD-like superfamily CL1_1641 da1933dd9e99d48efb93951e1d717b97 255 SUPERFAMILY SSF88713 1 252 1.33E-104 T 30-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CL1_1641 da1933dd9e99d48efb93951e1d717b97 255 Pfam PF03746 LamB/YcsF family 3 241 8.4E-105 T 30-10-2018 IPR005501 UPF0271 family, LamB/YcsF/PxpA KEGG: 00480+3.5.2.9|MetaCyc: PWY-4041|MetaCyc: PWY-7942 CL1_1641 da1933dd9e99d48efb93951e1d717b97 255 Gene3D G3DSA:3.20.20.370 1 255 9.2E-112 T 30-10-2018 CL1_1641 da1933dd9e99d48efb93951e1d717b97 255 Hamap MF_00691 UPF0271 protein YbgL [ybgL]. 1 245 47.477 T 30-10-2018 IPR005501 UPF0271 family, LamB/YcsF/PxpA KEGG: 00480+3.5.2.9|MetaCyc: PWY-4041|MetaCyc: PWY-7942 CL1_1953 c20cd6fe63b672af9ad7666395cb33c0 804 Gene3D G3DSA:3.30.70.2230 488 673 6.0E-39 T 30-10-2018 CL1_1953 c20cd6fe63b672af9ad7666395cb33c0 804 SUPERFAMILY SSF55073 592 674 5.41E-5 T 30-10-2018 IPR029787 Nucleotide cyclase CL1_1953 c20cd6fe63b672af9ad7666395cb33c0 804 TIGRFAM TIGR02578 cas_TM1811_Csm1: CRISPR-associated protein Cas10/Csm1, subtype III-A/MTUBE 96 664 2.3E-95 T 30-10-2018 IPR013408 CRISPR-associated protein Csm1 CL1_1945 74fe506f5df11f7e5f5a52820d019cd7 290 Pfam PF13588 Type I restriction enzyme R protein N terminus (HSDR_N) 25 119 6.7E-9 T 30-10-2018 IPR029464 Type I restriction enzyme R protein, N-terminal domain CL1_0418 8c0c48e83b65c02d1b538aa61ab2ce71 286 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 79 178 3.9E-16 T 30-10-2018 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 CL1_0418 8c0c48e83b65c02d1b538aa61ab2ce71 286 SUPERFAMILY SSF53474 22 286 1.18E-54 T 30-10-2018 IPR029058 Alpha/Beta hydrolase fold CL1_0418 8c0c48e83b65c02d1b538aa61ab2ce71 286 Gene3D G3DSA:3.40.50.1820 41 284 3.8E-47 T 30-10-2018 IPR029058 Alpha/Beta hydrolase fold CL1_1050 8e075215fc141149210a904135690318 127 Pfam PF04322 Protein of unknown function (DUF473) 1 111 6.9E-32 T 30-10-2018 IPR007417 Protein of unknown function DUF473 CL1_1050 8e075215fc141149210a904135690318 127 ProDom PD020987 PF0014 UNCHARACTERIZED AF1250 PH0127 MJ0105 MA4414 ARCHAEAL 1 92 1.0E-35 T 30-10-2018 IPR007417 Protein of unknown function DUF473 CL1_0243 0e564ebe94a45431fd8a77ebb187bf18 232 Pfam PF09968 Uncharacterized protein domain (DUF2202) 71 230 4.0E-64 T 30-10-2018 IPR019243 Domain of unknown function DUF2202 CL1_0243 0e564ebe94a45431fd8a77ebb187bf18 232 SUPERFAMILY SSF47240 64 210 2.71E-16 T 30-10-2018 IPR009078 Ferritin-like superfamily CL1_0243 0e564ebe94a45431fd8a77ebb187bf18 232 Gene3D G3DSA:1.20.1260.10 66 232 5.0E-68 T 30-10-2018 IPR012347 Ferritin-like CL1_0310 08496f5bcdb6cc2a225d86519646b363 210 Pfam PF09840 Uncharacterized protein conserved in archaea (DUF2067) 10 197 9.9E-50 T 30-10-2018 IPR019202 Protein of unknown function DUF2067 CL1_0197 c304a003122153a8693b9d99fa10da4f 614 Pfam PF00361 Proton-conducting membrane transporter 118 418 7.5E-54 T 30-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CL1_1463 4f2f91da3091d3bdf6b635bce991e7dc 87 Pfam PF01169 Uncharacterized protein family UPF0016 6 79 3.6E-23 T 30-10-2018 IPR001727 Gdt1 family CL1_1388 2de12d2f17f8cf8a7aba15fb797869c8 143 Pfam PF04024 PspC domain 4 61 3.4E-18 T 30-10-2018 IPR007168 Phage shock protein, PspC, N-terminal CL1_0193 bfebaa110f7202991041ce7f090828fa 94 Pfam PF13244 Domain of unknown function (DUF4040) 14 79 8.8E-20 T 30-10-2018 IPR025383 Domain of unknown function DUF4040 CL1_1837 228ad6b5baba399a931508fab19ad02f 100 Gene3D G3DSA:1.20.1260.10 7 75 1.4E-10 T 30-10-2018 IPR012347 Ferritin-like CL1_1837 228ad6b5baba399a931508fab19ad02f 100 Pfam PF02915 Rubrerythrin 24 90 4.5E-8 T 30-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 CL1_1837 228ad6b5baba399a931508fab19ad02f 100 SUPERFAMILY SSF47240 6 85 1.83E-19 T 30-10-2018 IPR009078 Ferritin-like superfamily CL1_0989 f758c58991203f9a08a86c3a3a6492c2 246 Pfam PF01925 Sulfite exporter TauE/SafE 7 240 1.4E-41 T 30-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 CL1_0041 5de1ba469bab05c3c4f927e9c27ef228 184 Pfam PF07826 IMP cyclohydrolase-like protein 2 173 7.3E-44 T 30-10-2018 IPR020600 Inosine monophosphate cyclohydrolase-like GO:0003937|GO:0006164|GO:0006188 KEGG: 00230+3.5.4.10|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 CL1_0041 5de1ba469bab05c3c4f927e9c27ef228 184 Gene3D G3DSA:3.60.20.20 1 182 2.2E-43 T 30-10-2018 IPR036795 Inosine monophosphate cyclohydrolase-like superfamily GO:0003937|GO:0006164|GO:0006188 KEGG: 00230+3.5.4.10|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 CL1_0041 5de1ba469bab05c3c4f927e9c27ef228 184 SUPERFAMILY SSF75569 2 181 2.09E-56 T 30-10-2018 IPR036795 Inosine monophosphate cyclohydrolase-like superfamily GO:0003937|GO:0006164|GO:0006188 KEGG: 00230+3.5.4.10|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 CL1_0041 5de1ba469bab05c3c4f927e9c27ef228 184 Hamap MF_00705 IMP cyclohydrolase [purO]. 1 184 59.785 T 30-10-2018 IPR010191 IMP cyclohydrolase GO:0003937|GO:0006164|GO:0006188 KEGG: 00230+3.5.4.10|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 CL1_1303 984e452a5817bacc0b0d37468a2f97b7 365 Pfam PF13699 Domain of unknown function (DUF4157) 109 151 1.3E-5 T 30-10-2018 IPR025295 Domain of unknown function DUF4157 CL1_0810 3cb74700825a056ef289d9caa4d7eb82 117 ProDom PD359573 MEMBRANE TRANSMEMBRANE AF2132 PROTEIN 1 87 1.0E-8 T 30-10-2018 CL1_0871 6067c2cba68ecd52c8f542ecb0493635 474 SUPERFAMILY SSF49303 40 119 8.63E-5 T 30-10-2018 IPR036156 Beta-Galactosidase/glucuronidase domain superfamily CL1_0847 61c0574594f64b1ad25e317ef4c7ecb6 427 Pfam PF01882 Protein of unknown function DUF58 181 264 4.0E-16 T 30-10-2018 IPR002881 Domain of unknown function DUF58 CL1_0837 b7832bbcb8dc961c71c52317d39f8073 448 SUPERFAMILY SSF53649 3 439 2.75E-38 T 30-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 CL1_0837 b7832bbcb8dc961c71c52317d39f8073 448 Pfam PF00884 Sulfatase 5 340 3.9E-23 T 30-10-2018 IPR000917 Sulfatase, N-terminal GO:0008484 CL1_0680 4362b1e219604f918ad3a2adcaaf0001 227 Pfam PF13680 Protein of unknown function (DUF4152) 1 224 6.7E-131 T 30-10-2018 IPR025206 Protein of unknown function DUF4152 CL1_0680 4362b1e219604f918ad3a2adcaaf0001 227 Gene3D G3DSA:3.30.420.440 1 227 1.2E-106 T 30-10-2018 CL1_0368 d94465aef0de497b861befbc211ad351 70 Gene3D G3DSA:1.10.10.10 1 70 1.3E-6 T 30-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily CL1_0368 d94465aef0de497b861befbc211ad351 70 Pfam PF13551 Winged helix-turn helix 4 61 3.0E-7 T 30-10-2018 CL1_0368 d94465aef0de497b861befbc211ad351 70 SUPERFAMILY SSF46785 4 55 6.63E-9 T 30-10-2018 IPR036390 Winged helix DNA-binding domain superfamily CL1_1858 f092a74738e2c143cf1a80a4e96edda2 233 Pfam PF12698 ABC-2 family transporter protein 38 219 5.5E-9 T 30-10-2018 CL1_0394 d1dc48b42dc5596a88f40a4c4077e45c 151 Pfam PF08905 Domain of unknown function (DUF1850) 41 119 1.8E-11 T 30-10-2018 IPR015001 Protein of unknown function DUF1850 CL1_1828 c5a8dff7ec8c3136fb0ba93ea4ef334a 213 Gene3D G3DSA:3.40.190.10 94 178 3.0E-63 T 30-10-2018 CL1_1828 c5a8dff7ec8c3136fb0ba93ea4ef334a 213 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 9 185 1.7E-59 T 30-10-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 CL1_1828 c5a8dff7ec8c3136fb0ba93ea4ef334a 213 ProSitePatterns PS01316 ATP phosphoribosyltransferase signature. 145 166 - T 30-10-2018 IPR018198 ATP phosphoribosyltransferase, conserved site GO:0003879 KEGG: 00340+2.4.2.17 CL1_1828 c5a8dff7ec8c3136fb0ba93ea4ef334a 213 SUPERFAMILY SSF53850 8 209 2.17E-60 T 30-10-2018 CL1_1828 c5a8dff7ec8c3136fb0ba93ea4ef334a 213 Pfam PF01634 ATP phosphoribosyltransferase 54 205 4.3E-48 T 30-10-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 CL1_1828 c5a8dff7ec8c3136fb0ba93ea4ef334a 213 Hamap MF_01018 ATP phosphoribosyltransferase [hisG]. 8 210 48.921 T 30-10-2018 IPR024893 ATP phosphoribosyltransferase HisG, short form GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17 CL1_1828 c5a8dff7ec8c3136fb0ba93ea4ef334a 213 Gene3D G3DSA:3.40.190.10 11 201 3.0E-63 T 30-10-2018 CL1_0507 4616042c51ff05c95d8977bb0b77d500 467 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 60 221 8.9E-19 T 30-10-2018 IPR038731 Glycosyltransferase RgtA/B/C/D-like CL1_0473 64d6aba07b35593e522e2acad316a501 60 SUPERFAMILY SSF54814 13 58 7.85E-8 T 30-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 CL1_0473 64d6aba07b35593e522e2acad316a501 60 Gene3D G3DSA:3.30.300.20 5 58 9.2E-9 T 30-10-2018 IPR015946 K homology domain-like, alpha/beta CL1_0473 64d6aba07b35593e522e2acad316a501 60 Pfam PF07650 KH domain 7 56 8.2E-6 T 30-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CL1_1429 89cf8d1d970ed88585a696af1786a774 96 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 9 92 1.1E-14 T 30-10-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like CL1_0897 dba2c24dc8bec9938d89df77ac11c983 247 SUPERFAMILY SSF53335 14 233 2.39E-24 T 30-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CL1_0897 dba2c24dc8bec9938d89df77ac11c983 247 Pfam PF05971 Protein of unknown function (DUF890) 34 163 2.3E-7 T 30-10-2018 IPR010286 Ribosomal RNA large subunit methyltransferase F-like GO:0008168 CL1_0897 dba2c24dc8bec9938d89df77ac11c983 247 Gene3D G3DSA:3.40.50.150 66 247 8.7E-38 T 30-10-2018 CL1_0058 0c82161752ad5067903f4976009a8fcc 264 SUPERFAMILY SSF55961 1 131 5.06E-6 T 30-10-2018 CL1_1859 935bc249337669e5d32206025fe9c73b 234 Pfam PF12698 ABC-2 family transporter protein 46 229 4.3E-8 T 30-10-2018 CL1_1292 e7dc5d62a23d580d8f802670d2de4a2b 193 Gene3D G3DSA:1.10.1760.20 1 193 4.5E-16 T 30-10-2018 CL1_0177 5a88c7d68696b0931c7c922800cc5c5d 78 Pfam PF07441 SigmaK-factor processing regulatory protein BofA 9 77 4.7E-7 T 30-10-2018 IPR010001 SigmaK-factor processing regulatory BofA CL1_1432 e71887092dac1c0a388dc42987f5cb6e 76 Pfam PF13244 Domain of unknown function (DUF4040) 11 73 5.6E-11 T 30-10-2018 IPR025383 Domain of unknown function DUF4040 CL1_1804 130c630f2955ff9a982076ae2a3680e5 585 Pfam PF02554 Carbon starvation protein CstA 1 367 2.5E-109 T 30-10-2018 IPR003706 CstA, N-terminal domain GO:0009267|GO:0016020 CL1_1804 130c630f2955ff9a982076ae2a3680e5 585 Pfam PF13722 5TM C-terminal transporter carbon starvation CstA 410 533 8.4E-32 T 30-10-2018 IPR025299 CstA, C-terminal domain CL1_0833 d6e789aec02bdd55df7cff6e973a78c2 327 Gene3D G3DSA:3.20.20.370 2 327 1.1E-8 T 30-10-2018 CL1_1279 4ebb69984905b2fa78824fff303dd34a 414 Pfam PF01882 Protein of unknown function DUF58 187 271 1.4E-25 T 30-10-2018 IPR002881 Domain of unknown function DUF58 CL1_1188 17f63479800013f4b9d33181f3d8b719 224 TIGRFAM TIGR00659 TIGR00659: TIGR00659 family protein 6 223 2.2E-82 T 30-10-2018 IPR005261 Conserved hypothetical protein CHP00659 CL1_1188 17f63479800013f4b9d33181f3d8b719 224 Pfam PF04172 LrgB-like family 9 221 7.8E-74 T 30-10-2018 IPR007300 CidB/LrgB family CL1_0985 e841855f0bf78504276be619bed93450 477 SUPERFAMILY SSF53649 15 462 1.43E-41 T 30-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 CL1_0985 e841855f0bf78504276be619bed93450 477 Gene3D G3DSA:3.40.720.10 4 304 1.2E-51 T 30-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 CL1_0985 e841855f0bf78504276be619bed93450 477 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 17 423 2.8E-65 T 30-10-2018 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 CL1_0050 8545598c5b6ce9b79e3d5c90965cbcd5 296 Pfam PF01384 Phosphate transporter family 5 288 7.2E-50 T 30-10-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 CL1_1298 94906477709d4aa71650c3227084de17 76 Pfam PF13396 Phospholipase_D-nuclease N-terminal 23 62 8.5E-6 T 30-10-2018 IPR027379 Cardiolipin synthase N-terminal CL1_0948 b19090f9689ba7a5e77f083161aa4598 172 Pfam PF03692 Putative zinc- or iron-chelating domain 16 126 6.4E-16 T 30-10-2018 IPR005358 Putative zinc- or iron-chelating domain containing protein CL1_0136 23098db9f68589bac6751554fc0c9210 403 SUPERFAMILY SSF52317 80 316 8.01E-6 T 30-10-2018 IPR029062 Class I glutamine amidotransferase-like CL1_1021 67016bc9675fee6a6f510195b3ee552e 299 Pfam PF00482 Type II secretion system (T2SS), protein F 101 225 5.0E-16 T 30-10-2018 IPR018076 Type II secretion system F domain CL1_1021 67016bc9675fee6a6f510195b3ee552e 299 Gene3D G3DSA:1.20.81.30 89 205 7.2E-7 T 30-10-2018 CL1_0194 1c036bd726a0bb6a2b61eff5e16b7a25 235 Pfam PF04039 Domain related to MnhB subunit of Na+/H+ antiporter 98 221 1.0E-23 T 30-10-2018 IPR007182 Na+/H+ antiporter MnhB subunit-related protein CL1_1692 52e017b69ee53065cf9197554a8ceaf4 268 Pfam PF01889 Membrane protein of unknown function DUF63 9 266 4.7E-73 T 30-10-2018 IPR002749 Protein of unknown function DUF63 CL1_1394 94b58d4a4c8a4b714e835a187bb11e80 158 Pfam PF02566 OsmC-like protein 54 141 8.1E-16 T 30-10-2018 IPR003718 OsmC/Ohr family CL1_1394 94b58d4a4c8a4b714e835a187bb11e80 158 SUPERFAMILY SSF82784 30 155 1.13E-31 T 30-10-2018 IPR036102 OsmC/Ohr superfamily CL1_1394 94b58d4a4c8a4b714e835a187bb11e80 158 Gene3D G3DSA:3.30.300.20 27 156 6.6E-34 T 30-10-2018 IPR015946 K homology domain-like, alpha/beta CL1_1002 a2d5888dd8f2b70362b5591a0c7e571a 205 Pfam PF02517 CAAX protease self-immunity 101 190 2.6E-12 T 30-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 CL1_0024 3cdb7929a0c15a1d3722c91c5f5e140d 297 Pfam PF02653 Branched-chain amino acid transport system / permease component 10 276 3.3E-33 T 30-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 CL1_0165 0a35052a4721812816ea626437ba643a 386 Pfam PF04412 Protein of unknown function (DUF521) 1 383 4.3E-149 T 30-10-2018 IPR007506 Aconitase X catalytic domain, putative CL1_1219 ebe736865f97513fb9cd2d1cb79bba9e 528 Pfam PF08308 PEGA domain 383 447 2.5E-7 T 30-10-2018 IPR013229 PEGA CL1_1812 3ea1521f2b678f49717baba0e1695195 156 TIGRFAM TIGR00372 cas4: CRISPR-associated protein Cas4 1 155 1.5E-29 T 30-10-2018 IPR013343 CRISPR-associated protein Cas4 CL1_1812 3ea1521f2b678f49717baba0e1695195 156 Gene3D G3DSA:3.90.320.10 1 156 2.7E-7 T 30-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal CL1_1812 3ea1521f2b678f49717baba0e1695195 156 Pfam PF01930 Domain of unknown function DUF83 1 155 2.6E-50 T 30-10-2018 IPR022765 Dna2/Cas4, domain of unknown function DUF83 CL1_1459 9e9b2596a93c9394f64bd10f05c5dede 99 Pfam PF09946 Predicted membrane protein (DUF2178) 5 85 1.7E-5 T 30-10-2018 IPR019235 Protein of unknown function DUF2178, transmembrane CL1_1524 06dd7febe4d1580dc9d00297293b2971 385 Gene3D G3DSA:3.40.50.12090 31 125 3.6E-5 T 30-10-2018 CL1_0756 9918eb0c9fc280d9be6a6c309ecc8c2d 340 Pfam PF17231 Family of unknown function (DUF5305) 134 328 7.6E-13 T 30-10-2018 IPR035185 Protein of unknown function DUF5305 CL1_1164 2e2b2f6420cfb22b817e8b76db51b55c 533 Pfam PF12679 ABC-2 family transporter protein 318 532 4.1E-16 T 30-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 CL1_1312 e96829e779152642e347bc012ba6bce9 169 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 18 161 4.0E-12 T 30-10-2018 IPR007404 LexA-binding, inner membrane-associated putative hydrolase CL1_0328 d0107e89f50de5776de308555da665f6 331 Pfam PF01594 AI-2E family transporter 9 322 2.1E-39 T 30-10-2018 IPR002549 Transmembrane protein TqsA-like CL1_1695 aa4901859a13a52d7a9d67fb303b2905 253 Pfam PF02361 Cobalt transport protein 11 204 5.7E-28 T 30-10-2018 IPR003339 ABC/ECF transporter, transmembrane component CL1_0900 5d0249a0ab95610d2338b814598d2b69 368 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 3 358 2.7E-36 T 30-10-2018 IPR002823 Protein of unknown function DUF112, transmembrane CL1_0583 217ce4fb1fa656754c399cff2f2e7bfb 99 Pfam PF04930 FUN14 family 12 96 8.1E-14 T 30-10-2018 IPR007014 FUN14 CL1_0774 3abd4e8195ff7904b8a5d59ca8808170 1143 Pfam PF10102 Domain of unknown function (DUF2341) 567 627 1.9E-9 T 30-10-2018 IPR018765 Domain of unknown function DUF2341 CL1_1341 b4df0f016fe436565938f605b1f043d5 302 Pfam PF00953 Glycosyl transferase family 4 69 215 1.4E-34 T 30-10-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 CL1_0114 f6dc698d5fcfce06d68bd57b65dcc399 238 Pfam PF01925 Sulfite exporter TauE/SafE 1 236 3.0E-51 T 30-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 CL1_0715 d88af2a4e128e146eac6bcd7e6f5d42e 125 SUPERFAMILY SSF50249 24 88 9.71E-6 T 30-10-2018 IPR012340 Nucleic acid-binding, OB-fold CL1_0198 f33066e7cf0db958466ce955b20174a6 297 Pfam PF00146 NADH dehydrogenase 11 296 2.7E-61 T 30-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CL1_0704 32c243015e70e54db24e0b8083690323 377 Pfam PF04123 Domain of unknown function (DUF373) 6 348 1.3E-97 T 30-10-2018 IPR007254 Protein of unknown function DUF373 CL1_1286 0225bdab45570338645c2f61b035e6c9 188 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 1 163 6.0E-26 T 30-10-2018 IPR007404 LexA-binding, inner membrane-associated putative hydrolase CL1_0879 9651a3a71d4cf5f5b1e27c2102fe8544 261 ProDom PD359573 MEMBRANE TRANSMEMBRANE AF2132 PROTEIN 54 157 8.0E-14 T 30-10-2018 CL1_0073 0b784e82b8ab6814d47e013c7435f514 293 Pfam PF03547 Membrane transport protein 2 130 1.2E-6 T 30-10-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 CL1_1026 d792a481b956cdcaf0b755015ebc50fd 111 TIGRFAM TIGR04076 TIGR04076: TIGR04076 family protein 1 96 1.8E-20 T 30-10-2018 IPR023811 Conserved hypothetical protein CHP04076 CL1_0172 8b01fc914cae1cf104ce4b7ebaa12c09 743 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 61 202 4.5E-18 T 30-10-2018 IPR038731 Glycosyltransferase RgtA/B/C/D-like CL1_1232 c6b454a959e50a353538143ee04eb4d6 197 PIRSF PIRSF004897 1 165 2.4E-46 T 30-10-2018 IPR014424 Uncharacterised conserved protein UCP004897, ACT- type CL1_1141 921b92be52b16efd29870a269d2ffbbc 87 Pfam PF04066 Multiple resistance and pH regulation protein F (MrpF / PhaF) 31 82 3.4E-21 T 30-10-2018 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 CL1_1454 aae1db38617f47a21f08364c3f51a3f8 269 Pfam PF02535 ZIP Zinc transporter 123 264 2.9E-20 T 30-10-2018 IPR003689 Zinc/iron permease GO:0016020|GO:0030001|GO:0046873|GO:0055085 CL1_0292 b57324f3dc225d3879fd9c11075b2e31 366 Pfam PF05763 Protein of unknown function (DUF835) 237 363 1.8E-31 T 30-10-2018 IPR008553 Domain of unknown function DUF835