locus-tag	class	description
TK0002	ENOG4108VKG	metal-dependent hydrolase
TK0005	ENOG4105K4P	CoA-binding domain protein
TK0012	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
TK0015	ENOG41066FR	extracellular solute-binding protein
TK0018	ENOG4105E0C	molybdate abc transporter
TK0019	ENOG41090JH	(ATPase)-like protein
TK0021	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
TK0026	ENOG4107XGZ	Hydrolase
TK0027	ENOG4108R96	Methyltransferase, YaeB family
TK0028	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
TK0030	ENOG4107VWA	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation (By similarity)
TK0037	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
TK0051	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
TK0052	ENOG4105EAC	phosphoserine phosphatase
TK0072	ENOG4105WE2	aldehyde ferredoxin oxidoreductase
TK0076	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
TK0107	ENOG4107R5H	iron (metal) dependent repressor, dtxr family
TK0110	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
TK0115	ENOG4105CK7	Sodium proline symporter
TK0121	ENOG4107KMQ	bfd domain protein (2fe-2s)-binding domain protein
TK0123	ENOG4108PK2	permease that is required for glycolipid anchoring of LTA. May facilitate the transport of diglucosyl- diacylglycerol (Glc2-DAG) from the inner to the outer leaflet of the cytoplasmic membrane, delivering Glc2-DAG as a substrate for LTA synthesis, thereby generating glycolipid-anchored LTA. Appears to play an important role in virulence
TK0125	ENOG41080E2	ribosomal-protein-alanine acetyltransferase
TK0141	ENOG4107WCI	zn-dependent hydrolase of the beta-lactamase fold-like protein
TK0147	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
TK0150	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
TK0155	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
TK0157	ENOG4105C7N	Xanthine uracil vitamin C permease
TK0158	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
TK0159	ENOG4105E0C	molybdate abc transporter
TK0161	ENOG4105CIG	ABC transporter
TK0174	ENOG4105NBF	ammecr1 domain protein
TK0180	ENOG4105CHU	acetyl-coa acetyltransferase
TK0181	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
TK0185	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
TK0186	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
TK0189	ENOG4108UKZ	OsmC family
TK0190	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
TK0193	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
TK0194	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
TK0197	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
TK0198	ENOG4107Y80	Major Facilitator superfamily
TK0200	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
TK0201	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
TK0204	ENOG4107QNG	Phosphoribosylglycinamide synthetase
TK0207	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
TK0208	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
TK0210	ENOG4105C8V	SAICAR synthetase
TK0214	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
TK0216	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
TK0217	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
TK0218	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
TK0219	ENOG4105CNB	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
TK0224	ENOG4108WVK	Could be a S-adenosyl-L-methionine-dependent methyltransferase (By similarity)
TK0233	ENOG4105KNA	-acetyltransferase
TK0234	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
TK0239	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
TK0240	ENOG4105CYW	agmatinase
TK0243	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
TK0245	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
TK0246	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
TK0247	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
TK0248	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
TK0249	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
TK0250	ENOG4105CIH	Imidazole acetol-phosphate transaminase
TK0252	ENOG4105DK0	Indole-3-glycerol phosphate synthase
TK0253	ENOG4107QYG	anthranilate phosphoribosyltransferase
TK0254	ENOG4105CRQ	synthase (Component I)
TK0257	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
TK0260	ENOG4105CHM	Aminotransferase
TK0262	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
TK0265	ENOG4105E2X	shikimate dehydrogenase
TK0266	ENOG4105FF2	Type I DHQase
TK0267	ENOG4105D49	3-dehydroquinate synthase
TK0268	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
TK0269	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
TK0272	ENOG4105II7	pyrroline-5-carboxylate reductase
TK0274	ENOG4108KB0	deacetylase
TK0275	ENOG4105C8Y	Acetylornithine aminotransferase
TK0277	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
TK0278	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
TK0280	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
TK0281	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
TK0282	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
TK0283	ENOG4108JZA	Homocitrate synthase
TK0284	ENOG4108TVJ	Nitroreductase
TK0288	ENOG4107SA6	carbon-phosphorus lyase complex accessory protein
TK0289	ENOG4105C6N	Formate acetyltransferase
TK0290	ENOG4105F1A	Pyruvate formate-lyase
TK0296	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
TK0297	ENOG4108IYU	L-aspartate oxidase
TK0305	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
TK0306	ENOG4105C1J	atp-dependent rna helicase
TK0307	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
TK0308	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
TK0309	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
TK0312	ENOG4105DCI	Phosphohydrolase
TK0313	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
TK0314	ENOG4105C5X	domain protein
TK0317	ENOG4105F8V	Hydrolase, tatD family
TK0326	ENOG4105DA5	(ABC) transporter
TK0327	ENOG4105DCG	PHP domain protein
TK0328	ENOG4105D5P	Methylmalonyl-coA mutase
TK0330	ENOG4108ZVT	methylmalonyl-coA epimerase
TK0333	ENOG4105P4J	Allophanate hydrolase, subunit 1
TK0336	ENOG4105E7W	lamb ycsf family protein
TK0338	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
TK0348	ENOG4107QX8	SPFH domain, Band 7 family protein
TK0349	ENOG4107QMS	site-determining protein
TK0352	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
TK0354	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
TK0357	ENOG4108T0W	nitrous oxide maturation protein NosY
TK0360	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
TK0364	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
TK0366	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
TK0368	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
TK0424	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
TK0425	ENOG4108R6K	riboflavin synthase, subunit alpha
TK0428	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
TK0429	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
TK0432	ENOG4105C8V	SAICAR synthetase
TK0434	ENOG4105IQJ	Involved in biosynthesis of the thiamine precursor thiazole (By similarity)
TK0435	ENOG4105DWF	phosphomethylpyrimidine kinase
TK0436	ENOG4105D5T	phosphonate abc transporter
TK0444	ENOG4105C8N	cysteinyl-tRNA synthetase
TK0445	ENOG4105ZHF	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
TK0455	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
TK0459	ENOG4105JF9	DNA polymerase III, delta
TK0460	ENOG4105DTT	CRISPR-associated helicase, cas3
TK0465	ENOG4105CD5	CoA-binding domain protein
TK0470	ENOG4106K5Q	Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication (By similarity)
TK0474	ENOG4105CYW	agmatinase
TK0475	ENOG4108VA3	3-hexulose-6-phosphate synthase
TK0492	ENOG4105C5S	asparaginyl-tRNA synthetase
TK0494	ENOG4105CH2	amidohydrolase
TK0504	ENOG4105CG9	aspartate racemase
TK0505	ENOG4105D7N	magnesium and cobalt transport protein CorA
TK0506	ENOG4105C3G	gtp-binding protein
TK0508	ENOG4108VVK	transcriptional Regulator, AsnC
TK0509	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
TK0511	ENOG4105CA9	Pyruvate kinase
TK0514	ENOG4105WMR	Protein CrcB homolog
TK0515	ENOG4105KJJ	Uncharacterized ACR, COG1993
TK0517	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
TK0519	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
TK0521	ENOG4108I5C	dEAD DEAH box helicase
TK0523	ENOG4108RAC	Rubrerythrin
TK0524	ENOG4105VCQ	rubredoxin
TK0525	ENOG4108YZ8	Superoxide reductase
TK0537	ENOG4105D3R	alkyl hydroperoxide reductase
TK0540	ENOG4105DCI	Phosphohydrolase
TK0541	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
TK0544	ENOG4105EPU	Molybdenum cofactor synthesis domain protein
TK0545	ENOG4105DZH	s-adenosylmethionine synthetase (EC 2.5.1.6)
TK0547	ENOG4107RFY	SbcCD D subunit
TK0548	ENOG4105CHM	Aminotransferase
TK0550	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
TK0551	ENOG4105C5I	Dehydrogenase
TK0556	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
TK0558	ENOG41080XQ	Signal transduction protein with cbs domains
TK0561	ENOG4105C83	adenylosuccinate lyase
TK0562	ENOG4105VYW	UPF0251 protein
TK0571	ENOG4105ECW	sulfate abc transporter
TK0572	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
TK0618	ENOG4105SC1	monovalent cation H antiporter subunit E
TK0620	ENOG4105KJM	monovalent cation h antiporter subunit g
TK0625	ENOG4108JPZ	Monovalent cation H antiporter subunit D
TK0626	ENOG4108ZP8	Acetolactate synthase small subunit
TK0629	ENOG4108V3W	Chemotaxis protein, CheW
TK0630	ENOG4108N3W	hemolysin secretion protein
TK0631	ENOG4105BZU	Histidine kinase
TK0632	ENOG4107YTP	response regulator receiver protein
TK0633	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
TK0634	ENOG4105CBS	Chea signal transduction histidine kinase
TK0635	ENOG4105CBS	Chea signal transduction histidine kinase
TK0638	ENOG4105C8Q	Methyl-accepting chemotaxis
TK0639	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
TK0645	ENOG4105SFS	phosphoesterase RecJ domain protein
TK0649	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
TK0653	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
TK0657	ENOG4105DIH	basic membrane
TK0658	ENOG4108JQ9	ABC transporter
TK0659	ENOG4105UIB	(ABC) transporter
TK0664	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
TK0665	ENOG4105CD5	CoA-binding domain protein
TK0669	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
TK0671	ENOG4105E0R	Deoxyhypusine synthase
TK0672	ENOG4105BZ8	glutamate synthase
TK0673	ENOG4105K6S	Short-chain dehydrogenase reductase Sdr
TK0675	ENOG4105C4X	radical SAM domain protein
TK0676	ENOG4105BZ1	(ABC) transporter
TK0677	ENOG4105D0M	Protease HtpX homolog
TK0678	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
TK0682	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
TK0683	ENOG4105C5I	Dehydrogenase
TK0685	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
TK0690	ENOG4108J2R	molybdopterin oxidoreductase
TK0701	ENOG4105D1F	ATP-binding protein
TK0703	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
TK0704	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
TK0705	ENOG4105C26	Dehydrogenase
TK0706	ENOG4105S10	periplasmic binding protein
TK0707	ENOG4105EHG	Permease protein
TK0708	ENOG4105E0A	ABC, transporter
TK0711	ENOG4108R96	Methyltransferase, YaeB family
TK0714	ENOG4105CE1	Ferrous iron transport protein b
TK0717	ENOG4107XNE	ABC transporter, periplasmic molybdate-binding protein
TK0719	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
TK0727	ENOG4105CJ1	ABC, transporter
TK0730	ENOG4105DIW	FeS assembly protein SUFB
TK0731	ENOG4105C3K	feS assembly ATPase SufC
TK0735	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
TK0736	ENOG4105CHR	reductase
TK0745	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
TK0746	ENOG4108JJB	ABC transporter
TK0747	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
TK0748	ENOG4105VKD	bioY protein
TK0752	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
TK0754	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
TK0757	ENOG4105DP9	ABC transporter
TK0758	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
TK0759	ENOG4105C5S	asparaginyl-tRNA synthetase
TK0762	ENOG4107QJZ	Glycosyl transferase, family 2
TK0764	ENOG4107QRT	dEAD DEAH box helicase
TK0764	ENOG4107QRT	dEAD DEAH box helicase
TK0768	ENOG4105VZ9	UPF0235 protein
TK0772	ENOG4105EYF	MMPL domain protein
TK0775	ENOG4105DER	m42 family
TK0777	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
TK0779	ENOG4105PW4	Sugar fermentation stimulation protein homolog
TK0781	ENOG4105CN9	Peptidase m42 family protein
TK0784	ENOG4105DVT	helicase
TK0786	ENOG4107ZXI	Rhomboid family
TK0787	ENOG4105ECY	inositol monophosphatase
TK0789	ENOG4107QW4	alcohol dehydrogenase
TK0793	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
TK0795	ENOG4105FBQ	ATPase associated with various cellular activities aaa_5
TK0799	ENOG41065SU	Two-component system sensor kinase
TK0803	ENOG4105FDK	ABC transporter
TK0805	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
TK0809	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
TK0812	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
TK0814	ENOG4105CNW	domain protein
TK0816	ENOG4105DQU	oxidoreductase, subunit beta
TK0819	ENOG4105E0X	reductase
TK0828	ENOG4108EQM	faD-dependent pyridine nucleotide-disulfide oxidoreductase
TK0834	ENOG4105EW9	transcriptional regulator AsnC family
TK0835	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
TK0836	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
TK0842	ENOG4105D6J	arsenicaL-resistance protein
TK0845	ENOG4105CPC	Aldo Keto reductase
TK0853	ENOG4108K7V	UPF0284 protein
TK0854	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
TK0856	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
TK0857	ENOG4108UHF	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
TK0863	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
TK0864	ENOG4105CIH	Imidazole acetol-phosphate transaminase
TK0865	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
TK0866	ENOG4105E3H	phosphoglycerate mutase
TK0870	ENOG41087GE	Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity)
TK0871	ENOG4105DBV	ornithine carbamoyltransferase
TK0880	ENOG4107R3E	Citrate transporter
TK0886	ENOG4105CMQ	Chloride channel
TK0890	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
TK0897	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
TK0899	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
TK0906	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
TK0908	ENOG4105HDK	L-asparaginase
TK0911	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
TK0916	ENOG4105CPQ	Dehydrogenase
TK0921	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
TK0927	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
TK0928	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
TK0929	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
TK0943	ENOG4105CD5	CoA-binding domain protein
TK0948	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
TK0950	ENOG4105CAQ	asparagine synthetase
TK0953	ENOG4105CTP	PilT protein domain protein
TK0954	ENOG4108Z03	MAF-like protein
TK0957	ENOG4105CE1	Ferrous iron transport protein b
TK0967	ENOG4105DC7	peptidase M24
TK0970	ENOG4108K3F	N(2),N(2)-dimethylguanosine tRNA methyltransferase
TK0974	ENOG4105UQX	Mate efflux family protein
TK0978	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
TK0981	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
TK0984	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
TK0986	ENOG4105CK2	sodium dicarboxylate symporter
TK0987	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
TK0989	ENOG41061GT	Aldolase
TK0990	ENOG4107QSA	Oxaloacetate decarboxylase
TK0991	ENOG4105D22	carbon starvation protein
TK0994	ENOG4105D0U	Arsenite-activated ATPase (ArsA)
TK0995	ENOG4105VG1	fes assembly suf system protein
TK0999	ENOG4105E5G	Alpha beta hydrolase fold
TK1002	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
TK1004	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
TK1009	ENOG4105FBQ	ATPase associated with various cellular activities aaa_5
TK1011	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
TK1015	ENOG4107QRT	dEAD DEAH box helicase
TK1017	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
TK1021	ENOG4105C1J	atp-dependent rna helicase
TK1026	ENOG4108RCS	geranylgeranylglyceryl phosphate synthase
TK1031	ENOG4108JJB	ABC transporter
TK1036	ENOG4105C2X	Arabinose 5-phosphate isomerase
TK1037	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
TK1045	ENOG4108WBT	adenosyltransferase
TK1047	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
TK1048	ENOG4105EHU	Circadian clock protein KaiC
TK1053	ENOG4105HF0	Membrane
TK1055	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
TK1066	ENOG4105WE2	aldehyde ferredoxin oxidoreductase
TK1071	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
TK1076	ENOG4106FRU	abrb family transcriptional regulator
TK1077	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
TK1081	ENOG4107QR0	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
TK1083	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
TK1085	ENOG4108JU3	Alkyl hydroperoxide reductase
TK1091	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
TK1094	ENOG4105CHM	Aminotransferase
TK1100	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
TK1103	ENOG4105CFT	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import (By similarity)
TK1106	ENOG4108JJB	ABC transporter
TK1111	ENOG4108Y83	glucose-6-phosphate isomerase
TK1114	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
TK1116	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
TK1119	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
TK1124	ENOG4105DQU	oxidoreductase, subunit beta
TK1125	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
TK1129	ENOG4105DQU	oxidoreductase, subunit beta
TK1130	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
TK1137	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
TK1139	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
TK1140	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
TK1141	ENOG4105CSM	endonuclease III
TK1146	ENOG4105BZA	Phosphoglycerate kinase
TK1155	ENOG4107Y70	Heat shock protein
TK1157	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
TK1161	ENOG4105EEI	dihydropteroate synthase
TK1162	ENOG4105F4G	Membrane
TK1170	ENOG4105C22	threonyL-tRNA synthetase
TK1173	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
TK1174	ENOG4108Z0R	Transferase
TK1177	ENOG4105CN9	Peptidase m42 family protein
TK1181	ENOG4108JJB	ABC transporter
TK1182	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
TK1183	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
TK1186	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
TK1188	ENOG4107V9E	glucose-1-phosphate thymidylyltransferase
TK1190	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
TK1193	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
TK1198	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
TK1199	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
TK1205	ENOG4108V1U	phospholipid-binding protein
TK1211	ENOG4108JPW	Aminotransferase
TK1215	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
TK1216	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
TK1217	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
TK1219	ENOG4108JPZ	Monovalent cation H antiporter subunit D
TK1220	ENOG4108JPZ	Monovalent cation H antiporter subunit D
TK1222	ENOG4105D65	subunit l
TK1224	ENOG4105KJM	monovalent cation h antiporter subunit g
TK1226	ENOG4105SC1	monovalent cation H antiporter subunit E
TK1228	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
TK1230	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
TK1231	ENOG4108IJ1	Dehydrogenase
TK1235	ENOG4105C75	arginyL-tRNA synthetase
TK1237	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
TK1251	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
TK1252	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
TK1257	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
TK1259	ENOG4108VVK	transcriptional Regulator, AsnC
TK1260	ENOG4108ZPQ	MazG nucleotide pyrophosphohydrolase
TK1261	ENOG4105KTU	Transcriptional regulator, arsr family
TK1264	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
TK1273	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
TK1274	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
TK1282	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
TK1284	ENOG4107R7Y	intracellular protease Pfpi family
TK1286	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
TK1287	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
TK1288	ENOG4105UQX	Mate efflux family protein
TK1289	ENOG4105UQX	Mate efflux family protein
TK1292	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
TK1299	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
TK1305	ENOG4107EEM	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
TK1307	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
TK1315	ENOG4105C11	sulfate adenylyltransferase), subunit 2
TK1316	ENOG4107QX8	SPFH domain, Band 7 family protein
TK1318	ENOG4107104	thymidine kinase
TK1323	ENOG4105E2K	Glycosyl transferase (Group 1
TK1324	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
TK1325	ENOG4105BZ8	glutamate synthase
TK1326	ENOG4105CDJ	oxidoreductase FAD NAD(P)-binding domain protein
TK1337	ENOG4105CJ1	ABC, transporter
TK1339	ENOG4105VZ8	Transcriptional regulator
TK1379	ENOG4107RGW	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
TK1392	ENOG4108JU3	Alkyl hydroperoxide reductase
TK1395	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
TK1396	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
TK1397	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
TK1398	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
TK1400	ENOG4107TE1	transport protein
TK1403	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
TK1405	ENOG4105C0M	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity)
TK1406	ENOG4107R76	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
TK1408	ENOG4105CX6	glutaminyL-tRNA synthetase
TK1414	ENOG4105DHP	deoxycytidine triphosphate deaminase
TK1417	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
TK1418	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
TK1421	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
TK1425	ENOG4108T9Q	UPF0278 protein
TK1426	ENOG4105E66	phosphoriboisomerase A
TK1428	ENOG4105CY0	Metallo-Beta-Lactamase
TK1429	ENOG4105KPK	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation (By similarity)
TK1431	ENOG4105D82	Glutamate dehydrogenase
TK1432	ENOG4105C8J	)-transporter
TK1435	ENOG4108YZA	Nitrogen regulatory protein pii
TK1436	ENOG4107RFW	hydrolase family 57
TK1439	ENOG4105MRR	Transcriptional regulator (By similarity)
TK1442	ENOG4108JEB	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
TK1443	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
TK1444	ENOG4107RDY	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
TK1445	ENOG4105CFH	Aspartokinase
TK1446	ENOG4107QYE	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
TK1461	ENOG4105C8T	Leucyl-tRNA synthetase
TK1466	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
TK1468	ENOG4105EAH	synthase
TK1470	ENOG4106UJV	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
TK1472	ENOG4105CEV	competence damage-inducible protein
TK1474	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
TK1477	ENOG41074MP	UPF0103 Mediator of ErbB2-driven cell motility-containing protein
TK1478	ENOG4108IYI	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
TK1479	ENOG4108I5U	Uridine phosphorylase
TK1481	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
TK1482	ENOG4105CB1	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
TK1486	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
TK1489	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
TK1491	ENOG4108YXU	transcriptional regulator AsnC family
TK1494	ENOG4105K7K	Transcriptional regulator
TK1496	ENOG4105CE9	30S ribosomal protein S2
TK1497	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
TK1500	ENOG4108UJD	30S ribosomal protein S9
TK1501	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
TK1503	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
TK1504	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
TK1505	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
TK1506	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
TK1507	ENOG4107Y49	methyltransferase
TK1509	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
TK1511	ENOG41071TK	Uncharacterised protein family (UPF0150)
TK1512	ENOG4105CHR	reductase
TK1514	ENOG4108Z4J	Cytidine monophosphate kinase
TK1519	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
TK1520	ENOG4105VPB	50S ribosomal protein L30
TK1521	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
TK1522	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
TK1525	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
TK1526	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
TK1528	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
TK1530	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
TK1531	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
TK1532	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
TK1535	ENOG41082SA	50s ribosomal protein l29
TK1536	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
TK1538	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
TK1539	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
TK1540	ENOG4105KZR	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
TK1542	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
TK1548	ENOG4105C5R	Aminotransferase
TK1550	ENOG4105C5S	asparaginyl-tRNA synthetase
TK1551	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
TK1556	ENOG4107R56	PP-loop domain protein
TK1557	ENOG4105DZ0	fad dependent oxidoreductase
TK1558	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
TK1559	ENOG4107RWR	Sodium hydrogen exchanger
TK1560	ENOG4107RWR	Sodium hydrogen exchanger
TK1561	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
TK1562	ENOG4105CUT	histidyl-tRNA synthetase
TK1567	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
TK1568	ENOG4105CK7	Sodium proline symporter
TK1572	ENOG4107XF7	NGG1p interacting factor 3 protein, NIF3
TK1588	ENOG4105DA5	(ABC) transporter
TK1590	ENOG4105EHU	Circadian clock protein KaiC
TK1592	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
TK1593	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
TK1594	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
TK1595	ENOG4105C1A	potassium transporter peripheral membrane
TK1599	ENOG4105K4G	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
TK1601	ENOG4105KXQ	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
TK1602	ENOG4108JIQ	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit (By similarity)
TK1606	ENOG4105EC8	Methyl-accepting chemotaxis
TK1607	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
TK1613	ENOG4107QIZ	NADH dehydrogenase
TK1615	ENOG4105CKX	Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP
TK1622	ENOG4105D8K	carboxyl transferase
TK1624	ENOG4107QSA	Oxaloacetate decarboxylase
TK1625	ENOG4105D9Q	decarboxylase (Beta subunit)
TK1626	ENOG4105C2X	Arabinose 5-phosphate isomerase
TK1627	ENOG4105D6E	homoserine dehydrogenase
TK1633	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
TK1634	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
TK1635	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
TK1643	ENOG4105DQU	oxidoreductase, subunit beta
TK1650	ENOG4108RWI	nicotinamidase
TK1652	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
TK1654	ENOG4105VUN	Transcriptional regulator
TK1656	ENOG4105HDK	L-asparaginase
TK1659	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
TK1673	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
TK1677	ENOG4105CHR	reductase
TK1684	ENOG4105BZ8	glutamate synthase
TK1685	ENOG4105CDJ	oxidoreductase FAD NAD(P)-binding domain protein
TK1687	ENOG4105C6T	cysteine synthase
TK1689	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
TK1691	ENOG4108JVH	Protein of unknown function DUF43
TK1693	ENOG4105VG1	fes assembly suf system protein
TK1694	ENOG41084T3	4fe-4S ferredoxin iron-sulfur binding domain-containing protein
TK1700	ENOG4105F0N	pyrophosphate phospho-hydrolase
TK1712	ENOG4105PSV	Polysaccharide Biosynthesis Protein
TK1717	ENOG4105K64	Glycosyl transferase, family 2
TK1731	ENOG4105E2K	Glycosyl transferase (Group 1
TK1732	ENOG410838F	Glycosyl transferase family 2
TK1733	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
TK1736	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
TK1736	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
TK1737	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
TK1738	ENOG41081HM	2'-5' rna ligase
TK1747	ENOG4108K16	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
TK1748	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
TK1755	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
TK1757	ENOG4105C3U	ABC transporter
TK1759	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
TK1764	ENOG4105FJR	Lmbe family
TK1768	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
TK1769	ENOG4108NGU	Transcriptional regulator
TK1771	ENOG4107FKK	extracellular solute-binding protein family 1
TK1772	ENOG4105D56	permease protein
TK1773	ENOG4105EG2	ABC transporter, permease
TK1777	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
TK1778	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
TK1779	ENOG4105EPD	Oligopeptide transporter, Opt family
TK1781	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
TK1784	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
TK1785	ENOG4105DR4	Methyltransferase
TK1789	ENOG4105EHU	Circadian clock protein KaiC
TK1796	ENOG4105C5F	glutamine synthetase
TK1798	ENOG4105C4K	Nad synthetase
TK1800	ENOG4108JQ7	(ABC) transporter
TK1801	ENOG4105C3U	ABC transporter
TK1802	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
TK1805	ENOG4105CD3	dihydroorotase
TK1806	ENOG4105DF0	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity)
TK1809	ENOG4105C6W	4-alpha-glucanotransferase (EC 2.4.1.25)
TK1820	ENOG4105C0H	protease
TK1821	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
TK1822	ENOG4105E4P	ATPase (AAA
TK1827	ENOG4105CS2	ec 3.2.1.21
TK1828	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
TK1829	ENOG4105D2S	major facilitator superfamily
TK1831	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
TK1835	ENOG4108KN7	Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity)
TK1836	ENOG4107SCK	Monooxygenase
TK1840	ENOG4105CTD	carboxy-peptidase
TK1843	ENOG4108KPW	sugar kinase
TK1846	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
TK1850	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
TK1857	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
TK1859	ENOG4107R39	(ABC) transporter
TK1861	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
TK1863	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
TK1864	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
TK1866	ENOG4105C8U	phosphate abc transporter
TK1867	ENOG4105E2Z	phosphate ABC transporter (Permease
TK1868	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
TK1872	ENOG4105ERH	Fumarylacetoacetate hydrolase
TK1878	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
TK1881	ENOG41082SX	arsR family transcriptional regulator
TK1884	ENOG4105E5K	Alpha-amylase
TK1886	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
TK1890	ENOG4105D1H	recombination factor protein RarA
TK1891	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
TK1893	ENOG4105D1Z	hydroxypyruvate reductase
TK1895	ENOG4105CB1	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
TK1898	ENOG4105CYV	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures (By similarity)
TK1900	ENOG4105EYW	Ion transport protein
TK1908	ENOG4107S5Z	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity)
TK1909	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
TK1910	ENOG4105EHU	Circadian clock protein KaiC
TK1932	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
TK1933	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
TK1936	ENOG4105CIG	ABC transporter
TK1940	ENOG4105D64	Mechanosensitive ion channel
TK1946	ENOG4105EM7	Selenocysteine-specific translation elongation factor
TK1954	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
TK1955	ENOG410825M	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
TK1957	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
TK1963	ENOG4105C6K	Malic enzyme
TK1966	ENOG4108JQ1	Dehydrogenase
TK1968	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
TK1970	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
TK1976	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
TK1977	ENOG4105CJ3	phosphate transporter
TK1980	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
TK1981	ENOG4105DDK	oxidoreductase, beta subunit
TK1982	ENOG4107XUH	ferredoxin (flavodoxin) oxidoreductase
TK1983	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
TK1984	ENOG4105DDK	oxidoreductase, beta subunit
TK1993	ENOG4105C45	hydrogenase expression formation protein (HypE)
TK1999	ENOG41090A1	ferritin
TK2000	ENOG4105CQS	hydrogenase expression formation protein HypD
TK2001	ENOG4105WRB	Hydrogenase assembly chaperone hypC hupF
TK2002	ENOG41083NF	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
TK2008	ENOG4105WMM	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
TK2009	ENOG4105PGM	cation diffusion facilitator family transporter
TK2019	ENOG4105EHG	Permease protein
TK2020	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
TK2021	ENOG4105D1F	ATP-binding protein
TK2026	ENOG4105CJ1	ABC, transporter
TK2029	ENOG4108RVA	ribokinase
TK2031	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
TK2033	ENOG4108UUC	Protein of unknown function DUF99
TK2034	ENOG4107YZX	Universal stress protein
TK2035	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
TK2037	ENOG4105VFR	signal peptidase
TK2040	ENOG4108IGT	Dipeptidase
TK2049	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
TK2059	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
TK2061	ENOG4107QXV	Phosphate transporter
TK2064	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
TK2065	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
TK2071	ENOG4107SHJ	sulfite reductase subunit b
TK2074	ENOG4105BZ8	glutamate synthase
TK2075	ENOG4105D3S	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
TK2076	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
TK2077	ENOG4105D3S	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
TK2078	ENOG4108ZNS	ferredoxin-type protein NapF
TK2079	ENOG4105TMB	Formate nitrite transporter
TK2081	ENOG41080TA	Multiple resistance and ph regulation protein f
TK2082	ENOG4105KJM	monovalent cation h antiporter subunit g
TK2087	ENOG4108JPZ	Monovalent cation H antiporter subunit D
TK2089	ENOG4105C47	NADH ubiquinone oxidoreductase 20 kda subunit
TK2090	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
TK2091	ENOG4108HM5	NADH-ubiquinone oxidoreductase chain 49kDa
TK2092	ENOG4107TDF	Formate hydrogenlyase subunit 4
TK2100	ENOG4105C3M	thioredoxin reductase
TK2101	ENOG4108JPW	Aminotransferase
TK2104	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
TK2106	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
TK2110	ENOG4105EW9	transcriptional regulator AsnC family
TK2115	ENOG4108ZAF	Molybdopterin
TK2122	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
TK2124	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
TK2126	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
TK2130	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
TK2132	ENOG4108S8N	class II Aldolase
TK2134	ENOG4108VVK	transcriptional Regulator, AsnC
TK2137	ENOG4107U53	septum site-determining protein minD
TK2138	ENOG4107SW0	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
TK2142	ENOG4107S6Z	Na H antiporter
TK2143	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
TK2145	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
TK2147	ENOG4105C8Q	Methyl-accepting chemotaxis
TK2149	ENOG4105VAW	lrga family
TK2150	ENOG41067MG	lrgb family
TK2160	ENOG4107ZBH	radical SAM domain protein
TK2161	ENOG4105CJ1	ABC, transporter
TK2164	ENOG4107NFR	Fructose-1,6-bisphosphatase
TK2169	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
TK2185	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
TK2195	ENOG4108R9M	Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity)
TK2196	ENOG4105CXT	aspartate transcarbamylase
TK2203	ENOG4105NBF	ammecr1 domain protein
TK2209	ENOG4105EHG	Permease protein
TK2211	ENOG4107WZZ	SMC domain protein
TK2211	ENOG4107WZZ	SMC domain protein
TK2214	ENOG4108Z24	l-2,4-diaminobutyric acid acetyltransferase
TK2217	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
TK2218	ENOG4105CDU	Replicative dna helicase
TK2225	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
TK2231	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
TK2232	ENOG4105E8R	UPF0173 metal-dependent hydrolase
TK2235	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
TK2240	ENOG4105DK7	lysyl-tRNA synthetase
TK2241	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
TK2246	ENOG4105D44	asparaginase
TK2248	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
TK2251	ENOG4105DJB	Major Facilitator Superfamily
TK2252	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
TK2254	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
TK2255	ENOG4107XGZ	Hydrolase
TK2257	ENOG4108UK2	deaminase
TK2258	ENOG4105D0M	Protease HtpX homolog
TK2260	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
TK2263	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
TK2268	ENOG4105CHM	Aminotransferase
TK2271	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
TK2272	ENOG4107QJE	Chromosome Partitioning Protein
TK2274	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
TK2276	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
TK2279	ENOG4108Y5D	Inherit from COG: cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
TK2281	ENOG4105CJ1	ABC, transporter
TK2290	ENOG4105DT1	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate
TK2294	ENOG4108RMN	UPF0128 protein
TK2302	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
TK2304	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B