TK0309 d684833b28d5266645e578b3c2f94a00 732 SUPERFAMILY SSF52540 10 268 1.84E-69 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK0309 d684833b28d5266645e578b3c2f94a00 732 Gene3D G3DSA:3.40.50.300 7 222 1.3E-72 T 31-10-2018 TK0309 d684833b28d5266645e578b3c2f94a00 732 Gene3D G3DSA:2.40.30.10 259 386 1.2E-28 T 31-10-2018 TK0309 d684833b28d5266645e578b3c2f94a00 732 SUPERFAMILY SSF54980 388 463 3.96E-24 T 31-10-2018 IPR035647 EF-G domain III/V-like TK0309 d684833b28d5266645e578b3c2f94a00 732 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 60 75 - T 31-10-2018 IPR031157 Tr-type G domain, conserved site TK0309 d684833b28d5266645e578b3c2f94a00 732 Pfam PF14492 Elongation Factor G, domain II 387 459 3.3E-27 T 31-10-2018 TK0309 d684833b28d5266645e578b3c2f94a00 732 SUPERFAMILY SSF50447 259 373 8.05E-34 T 31-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily TK0309 d684833b28d5266645e578b3c2f94a00 732 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 21 154 1.7E-20 T 31-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 TK0309 d684833b28d5266645e578b3c2f94a00 732 Pfam PF00679 Elongation factor G C-terminus 621 707 3.8E-24 T 31-10-2018 IPR000640 Elongation factor EFG, domain V-like TK0309 d684833b28d5266645e578b3c2f94a00 732 SMART SM00889 505 619 8.0E-21 T 31-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 TK0309 d684833b28d5266645e578b3c2f94a00 732 Pfam PF03764 Elongation factor G, domain IV 513 618 4.3E-27 T 31-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 TK0309 d684833b28d5266645e578b3c2f94a00 732 Gene3D G3DSA:3.30.70.870 388 465 1.0E-28 T 31-10-2018 TK0309 d684833b28d5266645e578b3c2f94a00 732 Hamap MF_00054_A Elongation factor G [fusA]. 2 725 44.116 T 31-10-2018 IPR004543 Translation elongation factor EFG/EF2, archaeal GO:0003746|GO:0005525|GO:0005737|GO:0006414 TK0309 d684833b28d5266645e578b3c2f94a00 732 TIGRFAM TIGR00490 aEF-2: translation elongation factor aEF-2 3 720 0.0 T 31-10-2018 IPR004543 Translation elongation factor EFG/EF2, archaeal GO:0003746|GO:0005525|GO:0005737|GO:0006414 TK0309 d684833b28d5266645e578b3c2f94a00 732 Pfam PF03144 Elongation factor Tu domain 2 306 372 1.6E-15 T 31-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 TK0309 d684833b28d5266645e578b3c2f94a00 732 Pfam PF00009 Elongation factor Tu GTP binding domain 20 257 1.9E-65 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TK0309 d684833b28d5266645e578b3c2f94a00 732 PRINTS PR00315 GTP-binding elongation factor signature 143 152 6.6E-16 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TK0309 d684833b28d5266645e578b3c2f94a00 732 PRINTS PR00315 GTP-binding elongation factor signature 67 75 6.6E-16 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TK0309 d684833b28d5266645e578b3c2f94a00 732 PRINTS PR00315 GTP-binding elongation factor signature 107 118 6.6E-16 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TK0309 d684833b28d5266645e578b3c2f94a00 732 PRINTS PR00315 GTP-binding elongation factor signature 23 36 6.6E-16 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TK0309 d684833b28d5266645e578b3c2f94a00 732 PRINTS PR00315 GTP-binding elongation factor signature 91 101 6.6E-16 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TK0309 d684833b28d5266645e578b3c2f94a00 732 Gene3D G3DSA:3.30.70.240 466 718 1.1E-75 T 31-10-2018 TK0309 d684833b28d5266645e578b3c2f94a00 732 SMART SM00838 621 708 5.5E-45 T 31-10-2018 IPR000640 Elongation factor EFG, domain V-like TK0309 d684833b28d5266645e578b3c2f94a00 732 SUPERFAMILY SSF54211 463 623 4.05E-49 T 31-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TK0309 d684833b28d5266645e578b3c2f94a00 732 Gene3D G3DSA:3.30.230.10 472 720 1.1E-75 T 31-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TK0309 d684833b28d5266645e578b3c2f94a00 732 SUPERFAMILY SSF54980 624 718 1.12E-23 T 31-10-2018 IPR035647 EF-G domain III/V-like TK0703 0eac63d72408c49566c4b4bff8604f82 315 SMART SM00729 15 228 0.0028 T 31-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TK0703 0eac63d72408c49566c4b4bff8604f82 315 Pfam PF04055 Radical SAM superfamily 25 192 6.7E-13 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TK0703 0eac63d72408c49566c4b4bff8604f82 315 SUPERFAMILY SSF102114 25 221 6.54E-21 T 31-10-2018 TK0703 0eac63d72408c49566c4b4bff8604f82 315 Gene3D G3DSA:3.20.20.70 20 240 1.2E-18 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TK0428 8d674bff2cc257342e5200d4bd3a5c8c 386 Pfam PF00925 GTP cyclohydrolase II 199 358 4.6E-68 T 31-10-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 TK0428 8d674bff2cc257342e5200d4bd3a5c8c 386 SUPERFAMILY SSF55821 2 185 5.72E-45 T 31-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily TK0428 8d674bff2cc257342e5200d4bd3a5c8c 386 TIGRFAM TIGR00505 ribA: GTP cyclohydrolase II 198 382 3.1E-68 T 31-10-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 TK0428 8d674bff2cc257342e5200d4bd3a5c8c 386 SUPERFAMILY SSF142695 193 360 4.05E-60 T 31-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 TK0428 8d674bff2cc257342e5200d4bd3a5c8c 386 Hamap MF_00179 GTP cyclohydrolase-2 [ribA]. 192 384 38.085 T 31-10-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 TK0428 8d674bff2cc257342e5200d4bd3a5c8c 386 Gene3D G3DSA:3.40.50.10990 194 359 3.0E-68 T 31-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 TK0428 8d674bff2cc257342e5200d4bd3a5c8c 386 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 12 185 8.2E-42 T 31-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TK0428 8d674bff2cc257342e5200d4bd3a5c8c 386 Gene3D G3DSA:3.90.870.10 5 193 9.8E-43 T 31-10-2018 TK0428 8d674bff2cc257342e5200d4bd3a5c8c 386 PIRSF PIRSF001259 1 386 6.4E-127 T 31-10-2018 TK0879 e7a24d3951c468c9f3549598928af50d 181 SUPERFAMILY SSF52402 65 180 5.11E-10 T 31-10-2018 TK0879 e7a24d3951c468c9f3549598928af50d 181 Pfam PF00582 Universal stress protein family 68 180 7.1E-5 T 31-10-2018 IPR006016 UspA TK0879 e7a24d3951c468c9f3549598928af50d 181 Gene3D G3DSA:3.40.50.620 33 181 1.5E-9 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TK0868 75443780a4f37ae9a747c49b60c23227 163 SUPERFAMILY SSF54197 1 156 9.07E-48 T 31-10-2018 IPR036265 HIT-like superfamily TK0868 75443780a4f37ae9a747c49b60c23227 163 Pfam PF01230 HIT domain 33 125 5.6E-15 T 31-10-2018 IPR001310 Histidine triad (HIT) protein TK0868 75443780a4f37ae9a747c49b60c23227 163 Gene3D G3DSA:3.30.428.10 1 162 3.6E-60 T 31-10-2018 IPR036265 HIT-like superfamily TK1765 9324141e49f98ce347ec3d5afaacf43c 1215 SUPERFAMILY SSF49384 775 848 9.07E-11 T 31-10-2018 IPR008965 CBM2/CBM3, carbohydrate-binding domain superfamily GO:0030246 TK1765 9324141e49f98ce347ec3d5afaacf43c 1215 SMART SM00636 175 528 2.0E-141 T 31-10-2018 IPR011583 Chitinase II GO:0008061 TK1765 9324141e49f98ce347ec3d5afaacf43c 1215 SUPERFAMILY SSF54556 425 499 3.66E-17 T 31-10-2018 IPR029070 Chitinase insertion domain superfamily TK1765 9324141e49f98ce347ec3d5afaacf43c 1215 SUPERFAMILY SSF51055 73 127 2.55E-15 T 31-10-2018 IPR036573 Carbohydrate-binding module superfamily 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 TK1765 9324141e49f98ce347ec3d5afaacf43c 1215 SMART SM00495 84 125 2.1E-13 T 31-10-2018 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 TK1765 9324141e49f98ce347ec3d5afaacf43c 1215 SMART SM00637 627 710 2.2E-17 T 31-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 TK1765 9324141e49f98ce347ec3d5afaacf43c 1215 SMART SM00637 772 853 1.3E-12 T 31-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 TK1765 9324141e49f98ce347ec3d5afaacf43c 1215 Pfam PF14600 Cellulose-binding domain 93 127 2.5E-6 T 31-10-2018 IPR032798 Endoglucanase Z, cellulose-binding domain KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 TK1765 9324141e49f98ce347ec3d5afaacf43c 1215 Pfam PF00553 Cellulose binding domain 794 846 6.2E-6 T 31-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 TK1765 9324141e49f98ce347ec3d5afaacf43c 1215 Pfam PF00553 Cellulose binding domain 650 714 1.9E-6 T 31-10-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 TK1765 9324141e49f98ce347ec3d5afaacf43c 1215 Gene3D G3DSA:3.20.20.80 907 1215 4.6E-102 T 31-10-2018 TK1765 9324141e49f98ce347ec3d5afaacf43c 1215 ProSitePatterns PS01095 Chitinases family 18 active site. 283 291 - T 31-10-2018 IPR001579 Glycoside hydrolase, chitinase active site GO:0004553|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 TK1765 9324141e49f98ce347ec3d5afaacf43c 1215 SUPERFAMILY SSF51445 914 1176 1.76E-24 T 31-10-2018 IPR017853 Glycoside hydrolase superfamily TK1765 9324141e49f98ce347ec3d5afaacf43c 1215 Gene3D G3DSA:2.60.40.290 764 863 1.6E-41 T 31-10-2018 IPR012291 CBM2, carbohydrate-binding domain superfamily GO:0004553|GO:0030247 TK1765 9324141e49f98ce347ec3d5afaacf43c 1215 SUPERFAMILY SSF51445 166 531 1.58E-94 T 31-10-2018 IPR017853 Glycoside hydrolase superfamily TK1765 9324141e49f98ce347ec3d5afaacf43c 1215 SUPERFAMILY SSF49384 630 707 3.91E-11 T 31-10-2018 IPR008965 CBM2/CBM3, carbohydrate-binding domain superfamily GO:0030246 TK1765 9324141e49f98ce347ec3d5afaacf43c 1215 Pfam PF00704 Glycosyl hydrolases family 18 176 528 3.0E-92 T 31-10-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 TK1765 9324141e49f98ce347ec3d5afaacf43c 1215 Gene3D G3DSA:2.10.10.20 61 131 2.7E-27 T 31-10-2018 TK1765 9324141e49f98ce347ec3d5afaacf43c 1215 Gene3D G3DSA:2.60.40.290 621 720 3.7E-42 T 31-10-2018 IPR012291 CBM2, carbohydrate-binding domain superfamily GO:0004553|GO:0030247 TK1765 9324141e49f98ce347ec3d5afaacf43c 1215 Gene3D G3DSA:3.10.50.10 428 501 9.2E-19 T 31-10-2018 IPR029070 Chitinase insertion domain superfamily TK0631 679ee677a5f2565b4371f7699b63e634 279 Pfam PF03705 CheR methyltransferase, all-alpha domain 9 59 7.7E-10 T 31-10-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal TK0631 679ee677a5f2565b4371f7699b63e634 279 SUPERFAMILY SSF53335 72 269 1.94E-49 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TK0631 679ee677a5f2565b4371f7699b63e634 279 SMART SM00138 10 271 1.6E-84 T 31-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 TK0631 679ee677a5f2565b4371f7699b63e634 279 Pfam PF01739 CheR methyltransferase, SAM binding domain 72 261 5.5E-57 T 31-10-2018 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal TK0631 679ee677a5f2565b4371f7699b63e634 279 PRINTS PR00996 Glutamate methyltransferase family signature 107 127 2.6E-36 T 31-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 TK0631 679ee677a5f2565b4371f7699b63e634 279 PRINTS PR00996 Glutamate methyltransferase family signature 210 224 2.6E-36 T 31-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 TK0631 679ee677a5f2565b4371f7699b63e634 279 PRINTS PR00996 Glutamate methyltransferase family signature 65 77 2.6E-36 T 31-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 TK0631 679ee677a5f2565b4371f7699b63e634 279 PRINTS PR00996 Glutamate methyltransferase family signature 143 159 2.6E-36 T 31-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 TK0631 679ee677a5f2565b4371f7699b63e634 279 PRINTS PR00996 Glutamate methyltransferase family signature 28 41 2.6E-36 T 31-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 TK0631 679ee677a5f2565b4371f7699b63e634 279 PRINTS PR00996 Glutamate methyltransferase family signature 229 252 2.6E-36 T 31-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 TK0631 679ee677a5f2565b4371f7699b63e634 279 Gene3D G3DSA:3.40.50.150 71 273 1.1E-64 T 31-10-2018 TK0631 679ee677a5f2565b4371f7699b63e634 279 SUPERFAMILY SSF47757 3 68 1.57E-12 T 31-10-2018 TK0455 2c9c9455eec6f55c9ebe3f45770b3a56 326 Pfam PF01867 CRISPR associated protein Cas1 7 281 8.5E-83 T 31-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 TK0455 2c9c9455eec6f55c9ebe3f45770b3a56 326 Gene3D G3DSA:1.20.120.920 83 326 1.2E-63 T 31-10-2018 TK0455 2c9c9455eec6f55c9ebe3f45770b3a56 326 TIGRFAM TIGR00287 cas1: CRISPR-associated endonuclease Cas1 6 321 2.5E-94 T 31-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 TK0455 2c9c9455eec6f55c9ebe3f45770b3a56 326 TIGRFAM TIGR03641 cas1_HMARI: CRISPR-associated endonuclease Cas1, subtype I-B/HMARI/TNEAP 5 325 9.1E-133 T 31-10-2018 IPR019858 CRISPR-associated protein Cas1, HMARI/TNEAP subtype GO:0004520|GO:0043571|GO:0046872 TK0455 2c9c9455eec6f55c9ebe3f45770b3a56 326 Hamap MF_01470 CRISPR-associated endonuclease Cas1 [cas1]. 3 311 24.69 T 31-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 TK0455 2c9c9455eec6f55c9ebe3f45770b3a56 326 Gene3D G3DSA:3.100.10.20 1 82 1.2E-30 T 31-10-2018 TK1936 24a1be66ff9078499fb00d28ea3e3bb6 222 Gene3D G3DSA:3.40.50.300 4 219 1.7E-43 T 31-10-2018 TK1936 24a1be66ff9078499fb00d28ea3e3bb6 222 Pfam PF00005 ABC transporter 18 154 8.6E-18 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TK1936 24a1be66ff9078499fb00d28ea3e3bb6 222 SUPERFAMILY SSF52540 7 208 6.76E-46 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK1936 24a1be66ff9078499fb00d28ea3e3bb6 222 SMART SM00382 26 203 7.1E-9 T 31-10-2018 IPR003593 AAA+ ATPase domain TK1936 24a1be66ff9078499fb00d28ea3e3bb6 222 ProSitePatterns PS00211 ABC transporters family signature. 127 141 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TK2134 949ba546c5c510f705421b3a84acce55 141 Pfam PF01037 Lrp/AsnC ligand binding domain 70 138 1.8E-15 T 31-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain TK2134 949ba546c5c510f705421b3a84acce55 141 SUPERFAMILY SSF54909 62 141 2.82E-17 T 31-10-2018 IPR011008 Dimeric alpha-beta barrel TK2134 949ba546c5c510f705421b3a84acce55 141 Gene3D G3DSA:1.10.10.10 1 52 2.6E-21 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TK2134 949ba546c5c510f705421b3a84acce55 141 Pfam PF13412 Winged helix-turn-helix DNA-binding 2 49 5.3E-15 T 31-10-2018 TK2134 949ba546c5c510f705421b3a84acce55 141 Gene3D G3DSA:3.30.70.920 65 141 1.7E-20 T 31-10-2018 TK2134 949ba546c5c510f705421b3a84acce55 141 SUPERFAMILY SSF46785 1 62 1.39E-18 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TK2134 949ba546c5c510f705421b3a84acce55 141 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 18 29 5.6E-16 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TK2134 949ba546c5c510f705421b3a84acce55 141 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 29 48 5.6E-16 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TK2134 949ba546c5c510f705421b3a84acce55 141 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 2 18 5.6E-16 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TK2134 949ba546c5c510f705421b3a84acce55 141 ProSitePatterns PS00519 AsnC-type HTH domain signature. 20 46 - T 31-10-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site TK2134 949ba546c5c510f705421b3a84acce55 141 SMART SM00344 2 108 1.8E-49 T 31-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 TK1082 e5802de5f7793c597c4eb7f71e562c56 906 SMART SM00663 211 515 3.3E-205 T 31-10-2018 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TK1082 e5802de5f7793c597c4eb7f71e562c56 906 Pfam PF04998 RNA polymerase Rpb1, domain 5 811 876 4.1E-29 T 31-10-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TK1082 e5802de5f7793c597c4eb7f71e562c56 906 SUPERFAMILY SSF64484 4 887 0.0 T 31-10-2018 TK1082 e5802de5f7793c597c4eb7f71e562c56 906 Gene3D G3DSA:2.40.40.20 311 482 3.9E-80 T 31-10-2018 TK1082 e5802de5f7793c597c4eb7f71e562c56 906 Pfam PF04997 RNA polymerase Rpb1, domain 1 6 319 6.5E-108 T 31-10-2018 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TK1082 e5802de5f7793c597c4eb7f71e562c56 906 Pfam PF04983 RNA polymerase Rpb1, domain 3 490 672 4.0E-38 T 31-10-2018 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TK1082 e5802de5f7793c597c4eb7f71e562c56 906 Pfam PF05000 RNA polymerase Rpb1, domain 4 698 804 1.0E-31 T 31-10-2018 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TK1082 e5802de5f7793c597c4eb7f71e562c56 906 Pfam PF00623 RNA polymerase Rpb1, domain 2 321 487 8.4E-74 T 31-10-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TK1082 e5802de5f7793c597c4eb7f71e562c56 906 Gene3D G3DSA:1.20.120.1280 1 123 9.3E-32 T 31-10-2018 TK1082 e5802de5f7793c597c4eb7f71e562c56 906 Gene3D G3DSA:1.20.120.1280 235 284 2.3E-11 T 31-10-2018 TK1082 e5802de5f7793c597c4eb7f71e562c56 906 Gene3D G3DSA:1.10.274.100 491 671 2.5E-67 T 31-10-2018 TK1082 e5802de5f7793c597c4eb7f71e562c56 906 Gene3D G3DSA:3.30.1490.180 354 418 3.9E-80 T 31-10-2018 TK1082 e5802de5f7793c597c4eb7f71e562c56 906 Gene3D G3DSA:1.10.132.30 672 813 5.0E-45 T 31-10-2018 IPR038120 RNA polymerase Rpb1, funnel domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TK1082 e5802de5f7793c597c4eb7f71e562c56 906 TIGRFAM TIGR02390 RNA_pol_rpoA1: DNA-directed RNA polymerase subunit A' 5 894 0.0 T 31-10-2018 IPR012758 DNA-directed RNA polymerase subunit A' (Rpo1N) GO:0003677|GO:0003899|GO:0006351|GO:0008270 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TK1082 e5802de5f7793c597c4eb7f71e562c56 906 Gene3D G3DSA:2.20.25.410 850 900 2.3E-22 T 31-10-2018 TK0511 976e9b9830908077236abf66944e02e9 478 Gene3D G3DSA:2.40.33.10 74 170 5.7E-166 T 31-10-2018 IPR015806 Pyruvate kinase, insert domain superfamily GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TK0511 976e9b9830908077236abf66944e02e9 478 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 6 478 5.8E-168 T 31-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TK0511 976e9b9830908077236abf66944e02e9 478 Pfam PF00224 Pyruvate kinase, barrel domain 6 338 2.8E-119 T 31-10-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TK0511 976e9b9830908077236abf66944e02e9 478 Gene3D G3DSA:3.20.20.60 7 336 5.7E-166 T 31-10-2018 TK0511 976e9b9830908077236abf66944e02e9 478 PRINTS PR01050 Pyruvate kinase family signature 314 330 2.5E-65 T 31-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TK0511 976e9b9830908077236abf66944e02e9 478 PRINTS PR01050 Pyruvate kinase family signature 188 202 2.5E-65 T 31-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TK0511 976e9b9830908077236abf66944e02e9 478 PRINTS PR01050 Pyruvate kinase family signature 270 294 2.5E-65 T 31-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TK0511 976e9b9830908077236abf66944e02e9 478 PRINTS PR01050 Pyruvate kinase family signature 63 79 2.5E-65 T 31-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TK0511 976e9b9830908077236abf66944e02e9 478 PRINTS PR01050 Pyruvate kinase family signature 295 313 2.5E-65 T 31-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TK0511 976e9b9830908077236abf66944e02e9 478 PRINTS PR01050 Pyruvate kinase family signature 218 244 2.5E-65 T 31-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TK0511 976e9b9830908077236abf66944e02e9 478 PRINTS PR01050 Pyruvate kinase family signature 245 269 2.5E-65 T 31-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TK0511 976e9b9830908077236abf66944e02e9 478 ProSitePatterns PS00110 Pyruvate kinase active site signature. 216 228 - T 31-10-2018 IPR018209 Pyruvate kinase, active site GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TK0511 976e9b9830908077236abf66944e02e9 478 SUPERFAMILY SSF51621 6 340 2.65E-94 T 31-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 TK0511 976e9b9830908077236abf66944e02e9 478 SUPERFAMILY SSF52935 324 478 3.27E-31 T 31-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TK0511 976e9b9830908077236abf66944e02e9 478 Pfam PF02887 Pyruvate kinase, alpha/beta domain 368 475 2.6E-22 T 31-10-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TK0511 976e9b9830908077236abf66944e02e9 478 Gene3D G3DSA:3.40.1380.20 337 474 5.7E-166 T 31-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TK0511 976e9b9830908077236abf66944e02e9 478 SUPERFAMILY SSF50800 75 167 5.76E-24 T 31-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily TK2081 0a9f4bda86b5c9a63423d7f963c0758c 84 Pfam PF04066 Multiple resistance and pH regulation protein F (MrpF / PhaF) 28 79 1.3E-21 T 31-10-2018 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 TK1392 66196d6eac58b8df507a284aa95de06f 413 Gene3D G3DSA:3.50.50.60 4 296 6.1E-53 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TK1392 66196d6eac58b8df507a284aa95de06f 413 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 111 129 1.0E-23 T 31-10-2018 TK1392 66196d6eac58b8df507a284aa95de06f 413 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 276 298 1.0E-23 T 31-10-2018 TK1392 66196d6eac58b8df507a284aa95de06f 413 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 158 176 1.0E-23 T 31-10-2018 TK1392 66196d6eac58b8df507a284aa95de06f 413 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 1.0E-23 T 31-10-2018 TK1392 66196d6eac58b8df507a284aa95de06f 413 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 248 264 1.0E-23 T 31-10-2018 TK1392 66196d6eac58b8df507a284aa95de06f 413 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 296 1.0E-29 T 31-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TK1392 66196d6eac58b8df507a284aa95de06f 413 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 206 222 2.5E-19 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TK1392 66196d6eac58b8df507a284aa95de06f 413 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 5 27 2.5E-19 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TK1392 66196d6eac58b8df507a284aa95de06f 413 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 61 71 2.5E-19 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TK1392 66196d6eac58b8df507a284aa95de06f 413 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 154 178 2.5E-19 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TK1392 66196d6eac58b8df507a284aa95de06f 413 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 286 304 2.5E-19 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TK1392 66196d6eac58b8df507a284aa95de06f 413 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 112 120 2.5E-19 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TK1392 66196d6eac58b8df507a284aa95de06f 413 Gene3D G3DSA:3.50.50.60 123 256 6.1E-53 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TK1392 66196d6eac58b8df507a284aa95de06f 413 SUPERFAMILY SSF51905 1 325 3.89E-43 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TK1874 eac0d09cc5a62000c25701c183925240 384 Gene3D G3DSA:3.40.50.620 1 255 6.1E-103 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TK1874 eac0d09cc5a62000c25701c183925240 384 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 208 229 2.1E-20 T 31-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 TK1874 eac0d09cc5a62000c25701c183925240 384 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 85 101 2.1E-20 T 31-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 TK1874 eac0d09cc5a62000c25701c183925240 384 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 252 262 2.1E-20 T 31-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 TK1874 eac0d09cc5a62000c25701c183925240 384 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 138 157 2.1E-20 T 31-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 TK1874 eac0d09cc5a62000c25701c183925240 384 Pfam PF00579 tRNA synthetases class I (W and Y) 73 347 1.3E-26 T 31-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 TK1874 eac0d09cc5a62000c25701c183925240 384 SUPERFAMILY SSF52374 4 368 5.63E-92 T 31-10-2018 TK1874 eac0d09cc5a62000c25701c183925240 384 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 81 90 - T 31-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 TK1874 eac0d09cc5a62000c25701c183925240 384 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 73 379 2.0E-105 T 31-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 TK1874 eac0d09cc5a62000c25701c183925240 384 Gene3D G3DSA:1.10.240.10 256 382 2.0E-43 T 31-10-2018 TK1874 eac0d09cc5a62000c25701c183925240 384 Hamap MF_00140_A Tryptophan--tRNA ligase [trpS]. 5 366 45.888 T 31-10-2018 IPR020653 Tryptophan-tRNA ligase, archaea GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 TK0553 a066077037188dad707f4c669b7902e5 424 Gene3D G3DSA:2.40.50.1010 252 401 7.1E-42 T 31-10-2018 TK0553 a066077037188dad707f4c669b7902e5 424 Pfam PF08489 Domain of unknown function (DUF1743) 140 253 1.2E-36 T 31-10-2018 IPR013696 Domain of unknown function DUF1743 TK0553 a066077037188dad707f4c669b7902e5 424 Pfam PF01336 OB-fold nucleic acid binding domain 269 341 1.8E-8 T 31-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 TK0553 a066077037188dad707f4c669b7902e5 424 Hamap MF_01892 tRNA(Ile2) 2-agmatinylcytidine synthetase TiaS [tiaS]. 3 422 36.526 T 31-10-2018 IPR024913 tRNA(Ile2) 2-agmatinylcytidine synthetase TiaS GO:0002101|GO:0016879 TK0553 a066077037188dad707f4c669b7902e5 424 Gene3D G3DSA:3.90.600.20 156 251 2.1E-34 T 31-10-2018 TK0553 a066077037188dad707f4c669b7902e5 424 Gene3D G3DSA:3.30.70.2200 1 155 2.1E-60 T 31-10-2018 TK1700 6310b31baaf1cd1c3d03f86224b8e0e8 178 SUPERFAMILY SSF50324 1 176 1.96E-68 T 31-10-2018 IPR036649 Inorganic pyrophosphatase superfamily GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 TK1700 6310b31baaf1cd1c3d03f86224b8e0e8 178 Gene3D G3DSA:3.90.80.10 1 178 1.9E-75 T 31-10-2018 IPR036649 Inorganic pyrophosphatase superfamily GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 TK1700 6310b31baaf1cd1c3d03f86224b8e0e8 178 Hamap MF_00209 Inorganic pyrophosphatase [ppa]. 15 171 36.466 T 31-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 TK1700 6310b31baaf1cd1c3d03f86224b8e0e8 178 ProSitePatterns PS00387 Inorganic pyrophosphatase signature. 66 72 - T 31-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 TK1700 6310b31baaf1cd1c3d03f86224b8e0e8 178 Pfam PF00719 Inorganic pyrophosphatase 20 171 1.7E-58 T 31-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 TK0686 4be5c9463f94d9228bedd36dc63b49de 242 Gene3D G3DSA:3.40.50.1000 3 220 8.5E-88 T 31-10-2018 IPR023214 HAD superfamily TK0686 4be5c9463f94d9228bedd36dc63b49de 242 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 93 195 9.1E-15 T 31-10-2018 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 TK0686 4be5c9463f94d9228bedd36dc63b49de 242 TIGRFAM TIGR02253 CTE7: HAD hydrolase, TIGR02253 family 1 221 3.0E-88 T 31-10-2018 IPR011950 HAD-superfamily hydrolase, subfamily IA, CTE7 GO:0016787 Reactome: R-HSA-4085001 TK0686 4be5c9463f94d9228bedd36dc63b49de 242 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 2 13 4.6E-13 T 31-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TK0686 4be5c9463f94d9228bedd36dc63b49de 242 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 106 119 4.6E-13 T 31-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TK0686 4be5c9463f94d9228bedd36dc63b49de 242 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 183 196 4.6E-13 T 31-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TK0686 4be5c9463f94d9228bedd36dc63b49de 242 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 137 153 4.6E-13 T 31-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TK0686 4be5c9463f94d9228bedd36dc63b49de 242 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 97 193 6.8E-13 T 31-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TK0686 4be5c9463f94d9228bedd36dc63b49de 242 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 107 188 2.4E-14 T 31-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TK0686 4be5c9463f94d9228bedd36dc63b49de 242 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 193 1.3E-33 T 31-10-2018 TK0686 4be5c9463f94d9228bedd36dc63b49de 242 Gene3D G3DSA:1.10.150.520 16 94 8.5E-88 T 31-10-2018 TK0686 4be5c9463f94d9228bedd36dc63b49de 242 SUPERFAMILY SSF56784 1 225 3.41E-50 T 31-10-2018 IPR036412 HAD-like superfamily TK0106 69f0cd505c9c368007daf6da5e26c10d 264 TIGRFAM TIGR00522 dph5: diphthine synthase 3 256 1.7E-106 T 31-10-2018 IPR004551 Diphthine synthase GO:0004164|GO:0017183 Reactome: R-HSA-5358493 TK0106 69f0cd505c9c368007daf6da5e26c10d 264 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 3 212 3.6E-21 T 31-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 TK0106 69f0cd505c9c368007daf6da5e26c10d 264 Gene3D G3DSA:3.30.950.10 115 264 1.9E-53 T 31-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 TK0106 69f0cd505c9c368007daf6da5e26c10d 264 Gene3D G3DSA:3.40.1010.10 1 114 1.5E-41 T 31-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 TK0106 69f0cd505c9c368007daf6da5e26c10d 264 Hamap MF_01084 Diphthine synthase [dphB]. 2 256 36.95 T 31-10-2018 IPR004551 Diphthine synthase GO:0004164|GO:0017183 Reactome: R-HSA-5358493 TK0106 69f0cd505c9c368007daf6da5e26c10d 264 PIRSF PIRSF036432 2 260 1.9E-100 T 31-10-2018 IPR004551 Diphthine synthase GO:0004164|GO:0017183 Reactome: R-HSA-5358493 TK0106 69f0cd505c9c368007daf6da5e26c10d 264 SUPERFAMILY SSF53790 1 260 5.89E-64 T 31-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 TK1446 b200ce6757e89ae0112579cae1893a65 336 Gene3D G3DSA:3.20.20.210 1 325 6.3E-106 T 31-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 TK1446 b200ce6757e89ae0112579cae1893a65 336 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 6 313 4.2E-56 T 31-10-2018 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 TK1446 b200ce6757e89ae0112579cae1893a65 336 SUPERFAMILY SSF51726 8 325 6.15E-77 T 31-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 TK1446 b200ce6757e89ae0112579cae1893a65 336 Hamap MF_00288 Methionine synthase [metE]. 6 318 46.474 T 31-10-2018 IPR022921 Methionine synthase MetE, archaeal GO:0008168|GO:0009086 TK1280 eaf2d7be2dc109683ef6326e2dd3157a 300 Gene3D G3DSA:1.10.472.170 6 197 2.4E-68 T 31-10-2018 TK1280 eaf2d7be2dc109683ef6326e2dd3157a 300 SUPERFAMILY SSF47954 206 298 3.74E-31 T 31-10-2018 IPR036915 Cyclin-like superfamily TK1280 eaf2d7be2dc109683ef6326e2dd3157a 300 Pfam PF00382 Transcription factor TFIIB repeat 117 186 1.0E-20 T 31-10-2018 IPR013150 Transcription factor TFIIB, cyclin-like domain GO:0017025 TK1280 eaf2d7be2dc109683ef6326e2dd3157a 300 Pfam PF00382 Transcription factor TFIIB repeat 212 282 1.1E-24 T 31-10-2018 IPR013150 Transcription factor TFIIB, cyclin-like domain GO:0017025 TK1280 eaf2d7be2dc109683ef6326e2dd3157a 300 ProSitePatterns PS00782 Transcription factor TFIIB repeat signature. 244 259 - T 31-10-2018 IPR023486 Transcription factor TFIIB, conserved site Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-674695|Reactome: R-HSA-6807505|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-76042 TK1280 eaf2d7be2dc109683ef6326e2dd3157a 300 ProSitePatterns PS00782 Transcription factor TFIIB repeat signature. 148 163 - T 31-10-2018 IPR023486 Transcription factor TFIIB, conserved site Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-674695|Reactome: R-HSA-6807505|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-76042 TK1280 eaf2d7be2dc109683ef6326e2dd3157a 300 PRINTS PR00685 Transcription initiation factor IIB signature 19 39 6.8E-63 T 31-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 TK1280 eaf2d7be2dc109683ef6326e2dd3157a 300 PRINTS PR00685 Transcription initiation factor IIB signature 245 261 6.8E-63 T 31-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 TK1280 eaf2d7be2dc109683ef6326e2dd3157a 300 PRINTS PR00685 Transcription initiation factor IIB signature 54 75 6.8E-63 T 31-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 TK1280 eaf2d7be2dc109683ef6326e2dd3157a 300 PRINTS PR00685 Transcription initiation factor IIB signature 182 197 6.8E-63 T 31-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 TK1280 eaf2d7be2dc109683ef6326e2dd3157a 300 PRINTS PR00685 Transcription initiation factor IIB signature 211 229 6.8E-63 T 31-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 TK1280 eaf2d7be2dc109683ef6326e2dd3157a 300 PRINTS PR00685 Transcription initiation factor IIB signature 156 175 6.8E-63 T 31-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 TK1280 eaf2d7be2dc109683ef6326e2dd3157a 300 PRINTS PR00685 Transcription initiation factor IIB signature 41 54 6.8E-63 T 31-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 TK1280 eaf2d7be2dc109683ef6326e2dd3157a 300 PRINTS PR00685 Transcription initiation factor IIB signature 277 291 6.8E-63 T 31-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 TK1280 eaf2d7be2dc109683ef6326e2dd3157a 300 SUPERFAMILY SSF47954 108 199 4.62E-28 T 31-10-2018 IPR036915 Cyclin-like superfamily TK1280 eaf2d7be2dc109683ef6326e2dd3157a 300 Pfam PF08271 TFIIB zinc-binding 6 47 2.2E-19 T 31-10-2018 IPR013137 Zinc finger, TFIIB-type TK1280 eaf2d7be2dc109683ef6326e2dd3157a 300 SUPERFAMILY SSF57783 4 50 2.95E-17 T 31-10-2018 TK1280 eaf2d7be2dc109683ef6326e2dd3157a 300 Gene3D G3DSA:1.10.472.10 207 300 3.2E-30 T 31-10-2018 TK1280 eaf2d7be2dc109683ef6326e2dd3157a 300 Hamap MF_00383 Transcription initiation factor IIB [tfb]. 1 297 45.024 T 31-10-2018 IPR023484 Transcription initiation factor TFIIB, archaea TK1280 eaf2d7be2dc109683ef6326e2dd3157a 300 SMART SM00385 210 291 1.0E-14 T 31-10-2018 IPR013763 Cyclin-like TK1280 eaf2d7be2dc109683ef6326e2dd3157a 300 SMART SM00385 114 195 1.1E-11 T 31-10-2018 IPR013763 Cyclin-like TK0219 f6edf85a9b7ee8b8ffee46168b4a770f 413 SUPERFAMILY SSF53448 1 382 7.66E-65 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TK0219 f6edf85a9b7ee8b8ffee46168b4a770f 413 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 352 383 2.9E-4 T 31-10-2018 IPR001451 Hexapeptide repeat TK0219 f6edf85a9b7ee8b8ffee46168b4a770f 413 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 325 351 0.0025 T 31-10-2018 IPR001451 Hexapeptide repeat TK0219 f6edf85a9b7ee8b8ffee46168b4a770f 413 Gene3D G3DSA:3.90.550.10 3 269 1.2E-66 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TK0219 f6edf85a9b7ee8b8ffee46168b4a770f 413 SUPERFAMILY SSF51161 222 401 1.18E-22 T 31-10-2018 IPR011004 Trimeric LpxA-like superfamily TK0219 f6edf85a9b7ee8b8ffee46168b4a770f 413 Pfam PF00483 Nucleotidyl transferase 4 253 5.1E-41 T 31-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 TK0219 f6edf85a9b7ee8b8ffee46168b4a770f 413 Gene3D G3DSA:2.160.10.10 351 410 1.5E-9 T 31-10-2018 TK0219 f6edf85a9b7ee8b8ffee46168b4a770f 413 Gene3D G3DSA:2.160.10.10 270 350 5.8E-8 T 31-10-2018 TK1790 15a13fc1a49e9b284d2024839a8adfa3 400 Hamap MF_00701 DNA primase large subunit PriL [priL]. 1 392 27.919 T 31-10-2018 IPR023642 DNA primase large subunit PriL GO:0003896 TK1790 15a13fc1a49e9b284d2024839a8adfa3 400 SUPERFAMILY SSF140914 2 253 1.44E-13 T 31-10-2018 TK1790 15a13fc1a49e9b284d2024839a8adfa3 400 Pfam PF04104 Eukaryotic and archaeal DNA primase, large subunit 147 367 2.3E-36 T 31-10-2018 IPR007238 DNA primase large subunit, eukaryotic/archaeal GO:0003896|GO:0006269 Reactome: R-HSA-113501|Reactome: R-HSA-174411|Reactome: R-HSA-174430|Reactome: R-HSA-68952|Reactome: R-HSA-68962|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183 TK1790 15a13fc1a49e9b284d2024839a8adfa3 400 Gene3D G3DSA:1.20.930.50 9 230 1.3E-38 T 31-10-2018 TK1790 15a13fc1a49e9b284d2024839a8adfa3 400 Gene3D G3DSA:2.20.20.80 113 175 1.3E-38 T 31-10-2018 TK0508 5af8f21668ea7b340b1a036927d79227 160 Gene3D G3DSA:1.10.10.10 1 56 8.2E-24 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TK0508 5af8f21668ea7b340b1a036927d79227 160 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 4 20 8.5E-13 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TK0508 5af8f21668ea7b340b1a036927d79227 160 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 31 50 8.5E-13 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TK0508 5af8f21668ea7b340b1a036927d79227 160 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 20 31 8.5E-13 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TK0508 5af8f21668ea7b340b1a036927d79227 160 SMART SM00344 4 116 6.0E-9 T 31-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 TK0508 5af8f21668ea7b340b1a036927d79227 160 Pfam PF13412 Winged helix-turn-helix DNA-binding 4 50 4.6E-16 T 31-10-2018 TK0508 5af8f21668ea7b340b1a036927d79227 160 SUPERFAMILY SSF46785 3 86 2.36E-14 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TK0508 5af8f21668ea7b340b1a036927d79227 160 Gene3D G3DSA:3.30.70.920 57 160 9.1E-33 T 31-10-2018 TK1508 5a7c0ab184ec96bfea5a3df58e55cdb8 265 ProDom PD359573 MEMBRANE TRANSMEMBRANE AF2132 PROTEIN 34 173 2.0E-75 T 31-10-2018 TK2251 65d0089056804ee74c9d7baf9e78d0cc 378 Pfam PF07690 Major Facilitator Superfamily 11 330 1.3E-44 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TK2251 65d0089056804ee74c9d7baf9e78d0cc 378 SUPERFAMILY SSF103473 2 363 1.03E-71 T 31-10-2018 IPR036259 MFS transporter superfamily TK2251 65d0089056804ee74c9d7baf9e78d0cc 378 Gene3D G3DSA:1.20.1250.20 190 369 6.2E-25 T 31-10-2018 TK2251 65d0089056804ee74c9d7baf9e78d0cc 378 Gene3D G3DSA:1.20.1250.20 1 184 9.7E-43 T 31-10-2018 TK1916 be86874f06936b3707e3a3639b97d67b 264 Gene3D G3DSA:3.60.110.10 1 263 5.1E-105 T 31-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily TK1916 be86874f06936b3707e3a3639b97d67b 264 SUPERFAMILY SSF56317 1 264 8.76E-77 T 31-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily TK1916 be86874f06936b3707e3a3639b97d67b 264 Pfam PF00795 Carbon-nitrogen hydrolase 2 244 9.7E-60 T 31-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 TK0867 b437b6aa11415de8c7124371eff964e7 311 TIGRFAM TIGR00367 TIGR00367: K+-dependent Na+/Ca+ exchanger homolog 5 301 6.1E-59 T 31-10-2018 IPR004481 Sodium/potassium/calcium exchanger Reactome: R-HSA-425561 TK0867 b437b6aa11415de8c7124371eff964e7 311 Pfam PF01699 Sodium/calcium exchanger protein 169 305 2.0E-21 T 31-10-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 TK0867 b437b6aa11415de8c7124371eff964e7 311 Pfam PF01699 Sodium/calcium exchanger protein 9 144 1.2E-20 T 31-10-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 TK0867 b437b6aa11415de8c7124371eff964e7 311 Gene3D G3DSA:1.20.1420.30 37 298 2.2E-75 T 31-10-2018 TK0867 b437b6aa11415de8c7124371eff964e7 311 Gene3D G3DSA:1.20.58.1130 11 199 2.2E-75 T 31-10-2018 TK1237 08539642b903408300cd9034e4b84e76 292 SUPERFAMILY SSF51569 2 289 1.57E-77 T 31-10-2018 TK1237 08539642b903408300cd9034e4b84e76 292 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 131 161 - T 31-10-2018 IPR020625 Schiff base-forming aldolase, active site GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 TK1237 08539642b903408300cd9034e4b84e76 292 Gene3D G3DSA:3.20.20.70 1 291 5.1E-87 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TK1237 08539642b903408300cd9034e4b84e76 292 PRINTS PR00146 Dihydrodipicolinate synthase signature 34 55 2.1E-17 T 31-10-2018 IPR002220 DapA-like GO:0016829 TK1237 08539642b903408300cd9034e4b84e76 292 PRINTS PR00146 Dihydrodipicolinate synthase signature 101 117 2.1E-17 T 31-10-2018 IPR002220 DapA-like GO:0016829 TK1237 08539642b903408300cd9034e4b84e76 292 PRINTS PR00146 Dihydrodipicolinate synthase signature 126 143 2.1E-17 T 31-10-2018 IPR002220 DapA-like GO:0016829 TK1237 08539642b903408300cd9034e4b84e76 292 PRINTS PR00146 Dihydrodipicolinate synthase signature 69 87 2.1E-17 T 31-10-2018 IPR002220 DapA-like GO:0016829 TK1237 08539642b903408300cd9034e4b84e76 292 PIRSF PIRSF001365 1 292 3.8E-78 T 31-10-2018 IPR002220 DapA-like GO:0016829 TK1237 08539642b903408300cd9034e4b84e76 292 SMART SM01130 1 292 6.2E-92 T 31-10-2018 IPR002220 DapA-like GO:0016829 TK1237 08539642b903408300cd9034e4b84e76 292 Pfam PF00701 Dihydrodipicolinate synthetase family 2 288 5.3E-60 T 31-10-2018 IPR002220 DapA-like GO:0016829 TK1198 a052ba1b14c835c58bc1fca975be47b4 253 Gene3D G3DSA:3.20.20.70 4 253 5.9E-27 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TK1198 a052ba1b14c835c58bc1fca975be47b4 253 PIRSF PIRSF000370 1 253 5.4E-32 T 31-10-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 TK1198 a052ba1b14c835c58bc1fca975be47b4 253 SUPERFAMILY SSF102114 32 211 4.45E-13 T 31-10-2018 TK1198 a052ba1b14c835c58bc1fca975be47b4 253 Hamap MF_00917 7-carboxy-7-deazaguanine synthase [queE]. 3 253 40.158 T 31-10-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 TK1198 a052ba1b14c835c58bc1fca975be47b4 253 Pfam PF04055 Radical SAM superfamily 31 191 2.3E-15 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TK1198 a052ba1b14c835c58bc1fca975be47b4 253 Pfam PF13353 4Fe-4S single cluster domain 29 146 2.1E-8 T 31-10-2018 TK0475 3c10454a93313ae9e828f76efdb91557 406 Gene3D G3DSA:3.20.20.70 1 208 2.6E-76 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TK0475 3c10454a93313ae9e828f76efdb91557 406 Pfam PF01380 SIS domain 246 347 7.3E-21 T 31-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 TK0475 3c10454a93313ae9e828f76efdb91557 406 SUPERFAMILY SSF53697 215 404 2.22E-40 T 31-10-2018 TK0475 3c10454a93313ae9e828f76efdb91557 406 SUPERFAMILY SSF51366 2 213 2.83E-45 T 31-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 TK0475 3c10454a93313ae9e828f76efdb91557 406 TIGRFAM TIGR03127 RuMP_HxlB: 6-phospho 3-hexuloisomerase 219 406 1.1E-76 T 31-10-2018 IPR017552 3-hexulose-6-phosphate isomerase GO:0016853 TK0475 3c10454a93313ae9e828f76efdb91557 406 Gene3D G3DSA:3.40.50.10490 213 406 8.9E-59 T 31-10-2018 TK0475 3c10454a93313ae9e828f76efdb91557 406 TIGRFAM TIGR03128 RuMP_HxlA: 3-hexulose-6-phosphate synthase 3 206 8.4E-85 T 31-10-2018 IPR017553 3-hexulose-6-phosphate synthase GO:0005975|GO:0043801 KEGG: 00030+4.1.2.43|KEGG: 00680+4.1.2.43|MetaCyc: PWY-1861|MetaCyc: PWY-7796 TK0475 3c10454a93313ae9e828f76efdb91557 406 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 3 203 3.8E-28 T 31-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TK0475 3c10454a93313ae9e828f76efdb91557 406 SMART SM00934 2 203 4.8E-45 T 31-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TK1895 2b2a16a07d48b62259515b9525fa9e66 257 TIGRFAM TIGR01694 MTAP: methylthioadenosine phosphorylase 4 237 3.1E-100 T 31-10-2018 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112|Reactome: R-HSA-8950505 TK1895 2b2a16a07d48b62259515b9525fa9e66 257 ProSitePatterns PS01240 Purine and other phosphorylases family 2 signature. 48 88 - T 31-10-2018 IPR018099 Purine phosphorylase, family 2, conserved site GO:0016763 TK1895 2b2a16a07d48b62259515b9525fa9e66 257 SUPERFAMILY SSF53167 1 255 4.84E-92 T 31-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 TK1895 2b2a16a07d48b62259515b9525fa9e66 257 Hamap MF_01963 S-methyl-5'-thioadenosine phosphorylase [mtnP]. 2 257 44.948 T 31-10-2018 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112|Reactome: R-HSA-8950505 TK1895 2b2a16a07d48b62259515b9525fa9e66 257 Gene3D G3DSA:3.40.50.1580 1 257 1.0E-102 T 31-10-2018 TK1895 2b2a16a07d48b62259515b9525fa9e66 257 Pfam PF01048 Phosphorylase superfamily 3 235 2.0E-49 T 31-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 TK0852 8893a0684aee846cd7366ee915f26873 262 Pfam PF13353 4Fe-4S single cluster domain 34 140 1.4E-6 T 31-10-2018 TK0852 8893a0684aee846cd7366ee915f26873 262 Gene3D G3DSA:3.20.20.70 22 243 1.4E-24 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TK0852 8893a0684aee846cd7366ee915f26873 262 Pfam PF04055 Radical SAM superfamily 39 205 1.7E-19 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TK0852 8893a0684aee846cd7366ee915f26873 262 SUPERFAMILY SSF102114 40 214 3.79E-23 T 31-10-2018 TK0975 8e0d0f77a493f2d4d65c7b9334f72b82 63 ProDom PD005132 RIBOSOMAL RRNA-BINDING METAL-BINDING RNA-BINDING ZINC RIBONUCLEOPROTEIN ZINC-FINGER L37 60S L37E 9 51 8.0E-18 T 31-10-2018 IPR001569 Ribosomal protein L37e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK0975 8e0d0f77a493f2d4d65c7b9334f72b82 63 Pfam PF01907 Ribosomal protein L37e 3 55 1.5E-21 T 31-10-2018 IPR001569 Ribosomal protein L37e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK0975 8e0d0f77a493f2d4d65c7b9334f72b82 63 ProSitePatterns PS01077 Ribosomal protein L37e signature. 4 24 - T 31-10-2018 IPR018267 Ribosomal protein L37e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK0975 8e0d0f77a493f2d4d65c7b9334f72b82 63 Gene3D G3DSA:2.20.25.30 1 57 1.3E-20 T 31-10-2018 IPR011331 Ribosomal protein L37ae/L37e GO:0003735|GO:0005622|GO:0005840|GO:0006412 TK0975 8e0d0f77a493f2d4d65c7b9334f72b82 63 Hamap MF_00547 50S ribosomal protein L37e [rpl37e]. 2 55 20.905 T 31-10-2018 IPR001569 Ribosomal protein L37e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK0975 8e0d0f77a493f2d4d65c7b9334f72b82 63 SUPERFAMILY SSF57829 1 56 2.2E-19 T 31-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 TK0651 ffc833523ecea84c0b080a9ada645e3e 329 SUPERFAMILY SSF51735 3 156 4.51E-44 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily TK0651 ffc833523ecea84c0b080a9ada645e3e 329 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 137 244 5.2E-7 T 31-10-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 TK0651 ffc833523ecea84c0b080a9ada645e3e 329 Gene3D G3DSA:3.30.360.10 125 311 1.6E-106 T 31-10-2018 TK0651 ffc833523ecea84c0b080a9ada645e3e 329 SUPERFAMILY SSF55347 129 260 2.29E-33 T 31-10-2018 TK0651 ffc833523ecea84c0b080a9ada645e3e 329 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 4 123 1.2E-21 T 31-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 TK0651 ffc833523ecea84c0b080a9ada645e3e 329 Gene3D G3DSA:3.40.50.720 5 291 1.6E-106 T 31-10-2018 TK2278 09cdc48da66bb9c1bc697e07df563255 382 Pfam PF01658 Myo-inositol-1-phosphate synthase 212 317 2.9E-20 T 31-10-2018 IPR013021 Myo-inositol-1-phosphate synthase, GAPDH-like KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 TK2278 09cdc48da66bb9c1bc697e07df563255 382 Gene3D G3DSA:3.30.360.10 216 319 1.2E-136 T 31-10-2018 TK2278 09cdc48da66bb9c1bc697e07df563255 382 SUPERFAMILY SSF51735 1 379 1.18E-75 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily TK2278 09cdc48da66bb9c1bc697e07df563255 382 PIRSF PIRSF015578 1 379 4.4E-98 T 31-10-2018 IPR002587 Myo-inositol-1-phosphate synthase GO:0004512|GO:0006021|GO:0008654 KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 TK2278 09cdc48da66bb9c1bc697e07df563255 382 SUPERFAMILY SSF55347 211 316 1.96E-28 T 31-10-2018 TK2278 09cdc48da66bb9c1bc697e07df563255 382 Gene3D G3DSA:3.40.50.720 3 354 1.2E-136 T 31-10-2018 TK2278 09cdc48da66bb9c1bc697e07df563255 382 Pfam PF07994 Myo-inositol-1-phosphate synthase 121 332 1.1E-8 T 31-10-2018 IPR002587 Myo-inositol-1-phosphate synthase GO:0004512|GO:0006021|GO:0008654 KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 TK1079 a64bc29f8c5d4a70b401cb3cb0d39c88 145 SUPERFAMILY SSF54814 12 74 2.29E-11 T 31-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 TK1079 a64bc29f8c5d4a70b401cb3cb0d39c88 145 Gene3D G3DSA:3.30.300.20 2 73 4.0E-27 T 31-10-2018 IPR015946 K homology domain-like, alpha/beta TK1079 a64bc29f8c5d4a70b401cb3cb0d39c88 145 Gene3D G3DSA:3.30.300.20 74 144 2.6E-23 T 31-10-2018 IPR015946 K homology domain-like, alpha/beta TK1079 a64bc29f8c5d4a70b401cb3cb0d39c88 145 Pfam PF07650 KH domain 12 94 4.0E-18 T 31-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1079 a64bc29f8c5d4a70b401cb3cb0d39c88 145 TIGRFAM TIGR01952 nusA_arch: NusA family KH domain protein, archaeal 1 145 1.5E-60 T 31-10-2018 IPR010212 Probable transcription termination protein NusA, archaeal TK1079 a64bc29f8c5d4a70b401cb3cb0d39c88 145 SUPERFAMILY SSF54814 76 141 2.68E-7 T 31-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 TK1079 a64bc29f8c5d4a70b401cb3cb0d39c88 145 Hamap MF_00945_A Transcription termination/antitermination protein NusA [nusA]. 1 145 30.453 T 31-10-2018 IPR010212 Probable transcription termination protein NusA, archaeal TK0076 062da720075d0dd873babd581c498c57 524 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 271 281 - T 31-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site TK0076 062da720075d0dd873babd581c498c57 524 Pfam PF00082 Subtilase family 230 488 5.2E-53 T 31-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 TK0076 062da720075d0dd873babd581c498c57 524 Gene3D G3DSA:3.40.50.200 203 508 1.8E-85 T 31-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 TK0076 062da720075d0dd873babd581c498c57 524 PRINTS PR00723 Subtilisin serine protease family (S8) signature 445 461 1.5E-21 T 31-10-2018 IPR015500 Peptidase S8, subtilisin-related TK0076 062da720075d0dd873babd581c498c57 524 PRINTS PR00723 Subtilisin serine protease family (S8) signature 230 249 1.5E-21 T 31-10-2018 IPR015500 Peptidase S8, subtilisin-related TK0076 062da720075d0dd873babd581c498c57 524 PRINTS PR00723 Subtilisin serine protease family (S8) signature 267 280 1.5E-21 T 31-10-2018 IPR015500 Peptidase S8, subtilisin-related TK0076 062da720075d0dd873babd581c498c57 524 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 235 246 - T 31-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site TK0076 062da720075d0dd873babd581c498c57 524 SUPERFAMILY SSF52743 212 507 1.83E-82 T 31-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 TK0076 062da720075d0dd873babd581c498c57 524 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 446 456 - T 31-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site TK1486 ea8af3492d7c6f7cdf08c99cc2c9adc2 448 SUPERFAMILY SSF52540 96 297 6.3E-50 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK1486 ea8af3492d7c6f7cdf08c99cc2c9adc2 448 SMART SM00963 2 87 2.8E-24 T 31-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 TK1486 ea8af3492d7c6f7cdf08c99cc2c9adc2 448 SUPERFAMILY SSF47446 297 429 8.5E-44 T 31-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 TK1486 ea8af3492d7c6f7cdf08c99cc2c9adc2 448 Gene3D G3DSA:1.10.260.30 310 443 3.9E-50 T 31-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 TK1486 ea8af3492d7c6f7cdf08c99cc2c9adc2 448 SUPERFAMILY SSF47364 1 94 2.36E-24 T 31-10-2018 IPR036225 SRP/SRP receptor, N-terminal Reactome: R-HSA-1799339 TK1486 ea8af3492d7c6f7cdf08c99cc2c9adc2 448 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 6 438 38.7 T 31-10-2018 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 TK1486 ea8af3492d7c6f7cdf08c99cc2c9adc2 448 Pfam PF02881 SRP54-type protein, helical bundle domain 6 83 4.3E-21 T 31-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 TK1486 ea8af3492d7c6f7cdf08c99cc2c9adc2 448 Pfam PF02978 Signal peptide binding domain 327 425 3.4E-34 T 31-10-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 TK1486 ea8af3492d7c6f7cdf08c99cc2c9adc2 448 Gene3D G3DSA:3.40.50.300 91 284 4.7E-124 T 31-10-2018 TK1486 ea8af3492d7c6f7cdf08c99cc2c9adc2 448 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 268 281 - T 31-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 TK1486 ea8af3492d7c6f7cdf08c99cc2c9adc2 448 Gene3D G3DSA:1.20.120.140 6 305 4.7E-124 T 31-10-2018 TK1486 ea8af3492d7c6f7cdf08c99cc2c9adc2 448 SMART SM00382 99 300 3.8E-6 T 31-10-2018 IPR003593 AAA+ ATPase domain TK1486 ea8af3492d7c6f7cdf08c99cc2c9adc2 448 SMART SM00962 100 295 6.1E-101 T 31-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 TK1486 ea8af3492d7c6f7cdf08c99cc2c9adc2 448 Pfam PF00448 SRP54-type protein, GTPase domain 100 295 1.1E-75 T 31-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 TK1768 be35f934826442c6c8dfc6b99b993c1f 448 Gene3D G3DSA:3.40.50.2000 2 436 1.1E-109 T 31-10-2018 TK1768 be35f934826442c6c8dfc6b99b993c1f 448 SUPERFAMILY SSF53756 1 439 2.16E-87 T 31-10-2018 TK1768 be35f934826442c6c8dfc6b99b993c1f 448 Pfam PF08323 Starch synthase catalytic domain 2 204 2.9E-35 T 31-10-2018 IPR013534 Starch synthase, catalytic domain KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 TK1768 be35f934826442c6c8dfc6b99b993c1f 448 Gene3D G3DSA:3.40.50.2000 218 426 1.1E-109 T 31-10-2018 TK1768 be35f934826442c6c8dfc6b99b993c1f 448 Pfam PF00534 Glycosyl transferases group 1 250 418 2.2E-25 T 31-10-2018 IPR001296 Glycosyl transferase, family 1 TK1123 963aaf1bf7e5b7a51494c3d4e9aa8505 186 Gene3D G3DSA:3.40.920.10 1 185 6.1E-54 T 31-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 TK1123 963aaf1bf7e5b7a51494c3d4e9aa8505 186 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 11 176 3.1E-33 T 31-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 TK1123 963aaf1bf7e5b7a51494c3d4e9aa8505 186 SUPERFAMILY SSF53323 1 180 2.75E-41 T 31-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 TK1621 85a66bd27507a6814625eba45306d2e3 142 Hamap MF_00232 Translation initiation factor 2 subunit beta [eif2b]. 8 142 33.43 T 31-10-2018 IPR004458 Translation initiation factor 2, beta subunit GO:0003743|GO:0006413 TK1621 85a66bd27507a6814625eba45306d2e3 142 Pfam PF01873 Domain found in IF2B/IF5 23 135 3.2E-37 T 31-10-2018 IPR002735 Translation initiation factor IF2/IF5 GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 TK1621 85a66bd27507a6814625eba45306d2e3 142 Gene3D G3DSA:3.30.70.3150 40 130 5.6E-32 T 31-10-2018 TK1621 85a66bd27507a6814625eba45306d2e3 142 TIGRFAM TIGR00311 aIF-2beta: putative translation initiation factor aIF-2, beta subunit 9 141 7.9E-52 T 31-10-2018 IPR004458 Translation initiation factor 2, beta subunit GO:0003743|GO:0006413 TK1621 85a66bd27507a6814625eba45306d2e3 142 SMART SM00653 29 136 6.8E-59 T 31-10-2018 IPR002735 Translation initiation factor IF2/IF5 GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 TK1621 85a66bd27507a6814625eba45306d2e3 142 SUPERFAMILY SSF75689 106 141 7.85E-12 T 31-10-2018 IPR016190 Translation initiation factor IF2/IF5, zinc-binding GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 TK1621 85a66bd27507a6814625eba45306d2e3 142 SUPERFAMILY SSF100966 8 109 1.96E-28 T 31-10-2018 IPR016189 Translation initiation factor IF2/IF5, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 TK2072 ac23ef5c3259b659f3aa663623a7ea6e 367 Pfam PF17179 4Fe-4S dicluster domain 233 326 1.3E-27 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TK2072 ac23ef5c3259b659f3aa663623a7ea6e 367 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 233 244 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TK2072 ac23ef5c3259b659f3aa663623a7ea6e 367 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 312 323 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TK2072 ac23ef5c3259b659f3aa663623a7ea6e 367 SUPERFAMILY SSF54862 226 327 4.6E-11 T 31-10-2018 TK1567 b78616848c75e3d5091f46de534da1ff 917 Gene3D G3DSA:3.30.54.20 679 730 1.4E-29 T 31-10-2018 TK1567 b78616848c75e3d5091f46de534da1ff 917 Gene3D G3DSA:3.30.980.10 609 678 1.0E-21 T 31-10-2018 TK1567 b78616848c75e3d5091f46de534da1ff 917 TIGRFAM TIGR03683 A-tRNA_syn_arch: alanine--tRNA ligase 4 916 0.0 T 31-10-2018 IPR022429 Alanine-tRNA ligase, archaea GO:0000166|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 TK1567 b78616848c75e3d5091f46de534da1ff 917 SUPERFAMILY SSF55681 57 267 3.48E-54 T 31-10-2018 TK1567 b78616848c75e3d5091f46de534da1ff 917 Pfam PF01411 tRNA synthetases class II (A) 61 607 7.4E-161 T 31-10-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 TK1567 b78616848c75e3d5091f46de534da1ff 917 Gene3D G3DSA:2.40.30.130 506 603 2.6E-37 T 31-10-2018 TK1567 b78616848c75e3d5091f46de534da1ff 917 Pfam PF02272 DHHA1 domain 786 915 4.1E-19 T 31-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 TK1567 b78616848c75e3d5091f46de534da1ff 917 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 706 748 8.5E-16 T 31-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 TK1567 b78616848c75e3d5091f46de534da1ff 917 PRINTS PR00980 Alanyl-tRNA synthetase signature 248 261 3.4E-21 T 31-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 TK1567 b78616848c75e3d5091f46de534da1ff 917 PRINTS PR00980 Alanyl-tRNA synthetase signature 209 220 3.4E-21 T 31-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 TK1567 b78616848c75e3d5091f46de534da1ff 917 PRINTS PR00980 Alanyl-tRNA synthetase signature 130 141 3.4E-21 T 31-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 TK1567 b78616848c75e3d5091f46de534da1ff 917 PRINTS PR00980 Alanyl-tRNA synthetase signature 363 376 3.4E-21 T 31-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 TK1567 b78616848c75e3d5091f46de534da1ff 917 PRINTS PR00980 Alanyl-tRNA synthetase signature 339 355 3.4E-21 T 31-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 TK1567 b78616848c75e3d5091f46de534da1ff 917 SMART SM00863 706 749 2.7E-18 T 31-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 TK1567 b78616848c75e3d5091f46de534da1ff 917 Gene3D G3DSA:3.30.930.10 1 263 8.5E-115 T 31-10-2018 TK1567 b78616848c75e3d5091f46de534da1ff 917 SUPERFAMILY SSF55186 607 756 2.49E-48 T 31-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 TK1567 b78616848c75e3d5091f46de534da1ff 917 SUPERFAMILY SSF50447 516 600 8.47E-19 T 31-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily TK1567 b78616848c75e3d5091f46de534da1ff 917 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 61 897 1.9E-232 T 31-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 TK1567 b78616848c75e3d5091f46de534da1ff 917 SUPERFAMILY SSF101353 308 516 6.15E-51 T 31-10-2018 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain superfamily GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 TK1567 b78616848c75e3d5091f46de534da1ff 917 Gene3D G3DSA:3.10.310.40 817 917 8.9E-21 T 31-10-2018 TK1567 b78616848c75e3d5091f46de534da1ff 917 Hamap MF_00036_A Alanine--tRNA ligase [alaS]. 4 913 24.103 T 31-10-2018 IPR022429 Alanine-tRNA ligase, archaea GO:0000166|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 TK0139 86b9dc0fa4aa94a42cb3a9cbad381fd6 458 SUPERFAMILY SSF52210 132 288 1.31E-44 T 31-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TK0139 86b9dc0fa4aa94a42cb3a9cbad381fd6 458 Gene3D G3DSA:3.40.50.720 3 129 6.4E-45 T 31-10-2018 TK0139 86b9dc0fa4aa94a42cb3a9cbad381fd6 458 SUPERFAMILY SSF51735 3 130 7.42E-38 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily TK0139 86b9dc0fa4aa94a42cb3a9cbad381fd6 458 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 150 287 4.2E-55 T 31-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain TK0139 86b9dc0fa4aa94a42cb3a9cbad381fd6 458 SMART SM00881 6 100 3.7E-33 T 31-10-2018 IPR003781 CoA-binding GO:0048037 TK0139 86b9dc0fa4aa94a42cb3a9cbad381fd6 458 Pfam PF13380 CoA binding domain 11 135 2.0E-24 T 31-10-2018 IPR003781 CoA-binding GO:0048037 TK0139 86b9dc0fa4aa94a42cb3a9cbad381fd6 458 Gene3D G3DSA:3.40.50.261 130 289 3.4E-60 T 31-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TK0139 86b9dc0fa4aa94a42cb3a9cbad381fd6 458 SUPERFAMILY SSF52210 292 451 8.24E-40 T 31-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TK0139 86b9dc0fa4aa94a42cb3a9cbad381fd6 458 Gene3D G3DSA:3.40.50.261 290 458 1.4E-66 T 31-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TK0499 529845d1342dc8c90735b10ac7d1ee45 441 Gene3D G3DSA:3.30.2290.10 1 206 1.5E-18 T 31-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal TK0499 529845d1342dc8c90735b10ac7d1ee45 441 SUPERFAMILY SSF111283 2 439 1.57E-95 T 31-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 TK0499 529845d1342dc8c90735b10ac7d1ee45 441 Pfam PF01523 Putative modulator of DNA gyrase 15 304 5.1E-47 T 31-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 TK0551 8099434a316b038b22e32fff96bd30b1 333 Gene3D G3DSA:3.40.50.720 95 286 1.2E-111 T 31-10-2018 TK0551 8099434a316b038b22e32fff96bd30b1 333 SUPERFAMILY SSF52283 1 131 6.8E-34 T 31-10-2018 TK0551 8099434a316b038b22e32fff96bd30b1 333 SUPERFAMILY SSF51735 98 287 1.57E-50 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily TK0551 8099434a316b038b22e32fff96bd30b1 333 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 5 318 2.7E-35 T 31-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 TK0551 8099434a316b038b22e32fff96bd30b1 333 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 106 286 1.5E-53 T 31-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 TK0551 8099434a316b038b22e32fff96bd30b1 333 Gene3D G3DSA:3.40.50.720 16 318 1.2E-111 T 31-10-2018 TK0551 8099434a316b038b22e32fff96bd30b1 333 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 149 176 - T 31-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 TK1313 40d6fcf7b8a097501c73e87e538d5201 203 SUPERFAMILY SSF75689 6 38 9.16E-5 T 31-10-2018 IPR016190 Translation initiation factor IF2/IF5, zinc-binding GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 TK1313 40d6fcf7b8a097501c73e87e538d5201 203 PIRSF PIRSF015877 1 199 2.0E-66 T 31-10-2018 IPR012041 Uncharacterised conserved protein UCP015877, zinc finger-containing TK1797 0036405e473636b542e09d706e1edbeb 287 SUPERFAMILY SSF103481 181 278 4.45E-18 T 31-10-2018 TK1797 0036405e473636b542e09d706e1edbeb 287 SUPERFAMILY SSF103481 38 140 2.35E-11 T 31-10-2018 TK1797 0036405e473636b542e09d706e1edbeb 287 Pfam PF00892 EamA-like transporter family 146 273 6.8E-27 T 31-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TK1797 0036405e473636b542e09d706e1edbeb 287 Pfam PF00892 EamA-like transporter family 3 137 3.1E-25 T 31-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TK0448 1f2bbb26eb6f439b52d3946ac792e465 225 Gene3D G3DSA:3.40.50.11700 3 140 3.5E-7 T 31-10-2018 TK0448 1f2bbb26eb6f439b52d3946ac792e465 225 Gene3D G3DSA:1.10.10.10 151 223 7.9E-9 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TK0448 1f2bbb26eb6f439b52d3946ac792e465 225 SUPERFAMILY SSF46785 162 217 1.42E-8 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TK0448 1f2bbb26eb6f439b52d3946ac792e465 225 Pfam PF13936 Helix-turn-helix domain 162 185 8.1E-7 T 31-10-2018 IPR025246 Transposase IS30-like HTH domain TK0448 1f2bbb26eb6f439b52d3946ac792e465 225 TIGRFAM TIGR01884 cas_HTH: CRISPR locus-related DNA-binding protein 3 211 5.1E-38 T 31-10-2018 IPR010163 CRISPR locus-related putative DNA-binding protein Csa3 TK2252 6cb06082e62c856177d6df89895330ee 397 TIGRFAM TIGR01242 26Sp45: 26S proteasome subunit P45 family 20 378 1.7E-200 T 31-10-2018 IPR005937 26S proteasome regulatory subunit P45-like GO:0005737|GO:0016787|GO:0030163 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 TK2252 6cb06082e62c856177d6df89895330ee 397 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 175 308 3.1E-44 T 31-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TK2252 6cb06082e62c856177d6df89895330ee 397 SMART SM00382 171 310 3.6E-24 T 31-10-2018 IPR003593 AAA+ ATPase domain TK2252 6cb06082e62c856177d6df89895330ee 397 Gene3D G3DSA:1.10.8.60 309 380 5.4E-30 T 31-10-2018 TK2252 6cb06082e62c856177d6df89895330ee 397 Pfam PF16450 Proteasomal ATPase OB/ID domain 65 121 2.1E-7 T 31-10-2018 IPR032501 Proteasomal ATPase, OB/ID domain TK2252 6cb06082e62c856177d6df89895330ee 397 Gene3D G3DSA:2.40.50.140 24 127 1.0E-27 T 31-10-2018 TK2252 6cb06082e62c856177d6df89895330ee 397 Gene3D G3DSA:3.40.50.300 128 308 7.5E-72 T 31-10-2018 TK2252 6cb06082e62c856177d6df89895330ee 397 ProSitePatterns PS00674 AAA-protein family signature. 278 296 - T 31-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 TK2252 6cb06082e62c856177d6df89895330ee 397 Hamap MF_00553 Proteasome-activating nucleotidase [pan]. 4 396 47.818 T 31-10-2018 IPR023501 Proteasome-activating nucleotidase PAN TK2252 6cb06082e62c856177d6df89895330ee 397 SUPERFAMILY SSF52540 133 381 2.51E-72 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK2263 b62db84a2b80b6a6b1b13925c9b3924c 239 Hamap MF_01633 7-cyano-7-deazaguanine synthase [queC]. 2 231 46.391 T 31-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 TK2263 b62db84a2b80b6a6b1b13925c9b3924c 239 Gene3D G3DSA:3.40.50.620 1 236 4.1E-61 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TK2263 b62db84a2b80b6a6b1b13925c9b3924c 239 PIRSF PIRSF006293 1 238 2.0E-70 T 31-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 TK2263 b62db84a2b80b6a6b1b13925c9b3924c 239 TIGRFAM TIGR00364 TIGR00364: queuosine biosynthesis protein QueC 4 218 6.9E-49 T 31-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 TK2263 b62db84a2b80b6a6b1b13925c9b3924c 239 Pfam PF06508 Queuosine biosynthesis protein QueC 3 224 8.2E-64 T 31-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 TK2263 b62db84a2b80b6a6b1b13925c9b3924c 239 SUPERFAMILY SSF52402 1 235 1.7E-51 T 31-10-2018 TK1526 ecd4499b28abc536b8d7326ba191ada1 130 Gene3D G3DSA:3.30.1490.10 70 128 3.9E-28 T 31-10-2018 TK1526 ecd4499b28abc536b8d7326ba191ada1 130 Pfam PF00410 Ribosomal protein S8 5 130 9.9E-28 T 31-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1526 ecd4499b28abc536b8d7326ba191ada1 130 Gene3D G3DSA:3.30.1370.30 1 69 2.8E-31 T 31-10-2018 TK1526 ecd4499b28abc536b8d7326ba191ada1 130 Hamap MF_01302_A 30S ribosomal protein S8 [rpsH]. 2 130 38.053 T 31-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1526 ecd4499b28abc536b8d7326ba191ada1 130 SUPERFAMILY SSF56047 3 130 6.67E-40 T 31-10-2018 IPR035987 Ribosomal protein S8 superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1526 ecd4499b28abc536b8d7326ba191ada1 130 ProSitePatterns PS00053 Ribosomal protein S8 signature. 100 117 - T 31-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK0424 44fbd0ca71e7a2b37ef14c0c98d438f2 353 SUPERFAMILY SSF53927 5 149 3.68E-51 T 31-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 TK0424 44fbd0ca71e7a2b37ef14c0c98d438f2 353 Pfam PF01872 RibD C-terminal domain 152 345 1.6E-35 T 31-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 TK0424 44fbd0ca71e7a2b37ef14c0c98d438f2 353 PIRSF PIRSF006769 1 352 2.3E-115 T 31-10-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-7991 TK0424 44fbd0ca71e7a2b37ef14c0c98d438f2 353 Gene3D G3DSA:3.40.430.10 147 352 6.9E-52 T 31-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 TK0424 44fbd0ca71e7a2b37ef14c0c98d438f2 353 TIGRFAM TIGR00326 eubact_ribD: riboflavin biosynthesis protein RibD 9 346 1.4E-104 T 31-10-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-7991 TK0424 44fbd0ca71e7a2b37ef14c0c98d438f2 353 Gene3D G3DSA:3.40.140.10 1 146 1.7E-53 T 31-10-2018 TK0424 44fbd0ca71e7a2b37ef14c0c98d438f2 353 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 52 93 - T 31-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 TK0424 44fbd0ca71e7a2b37ef14c0c98d438f2 353 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 4 105 4.8E-26 T 31-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain TK0424 44fbd0ca71e7a2b37ef14c0c98d438f2 353 SUPERFAMILY SSF53597 152 350 4.08E-45 T 31-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 TK2279 8274be992b184b845214c7209750ef07 432 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 295 317 - T 31-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 TK2279 8274be992b184b845214c7209750ef07 432 Pfam PF12804 MobA-like NTP transferase domain 6 116 2.4E-17 T 31-10-2018 IPR025877 MobA-like NTP transferase TK2279 8274be992b184b845214c7209750ef07 432 Gene3D G3DSA:3.90.550.10 4 220 1.8E-57 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TK2279 8274be992b184b845214c7209750ef07 432 Pfam PF01066 CDP-alcohol phosphatidyltransferase 254 317 4.3E-10 T 31-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 TK2279 8274be992b184b845214c7209750ef07 432 Gene3D G3DSA:1.20.120.1760 230 425 2.6E-56 T 31-10-2018 TK2279 8274be992b184b845214c7209750ef07 432 SUPERFAMILY SSF53448 5 221 5.63E-34 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TK1218 4c80b428a676e82f49b4ca64fce01497 297 Pfam PF00146 NADH dehydrogenase 11 296 3.1E-62 T 31-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TK1131 6d848e37b9d1631d93b4069e4052a885 90 Gene3D G3DSA:3.30.70.20 2 90 6.2E-17 T 31-10-2018 TK1131 6d848e37b9d1631d93b4069e4052a885 90 SUPERFAMILY SSF54862 25 88 6.65E-16 T 31-10-2018 TK1131 6d848e37b9d1631d93b4069e4052a885 90 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 71 82 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TK1131 6d848e37b9d1631d93b4069e4052a885 90 Pfam PF12838 4Fe-4S dicluster domain 34 82 5.6E-11 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TK1131 6d848e37b9d1631d93b4069e4052a885 90 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 34 45 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TK1169 a97651778fed7ce0b949feb8bcdb162f 198 Hamap MF_00975 Exosome complex component Csl4 [csl4]. 12 193 28.497 T 31-10-2018 IPR030850 Exosome complex component Csl4, archaea GO:0000178|GO:0006396 TK1169 a97651778fed7ce0b949feb8bcdb162f 198 SMART SM00316 68 149 1.8E-10 T 31-10-2018 IPR022967 RNA-binding domain, S1 TK1169 a97651778fed7ce0b949feb8bcdb162f 198 SUPERFAMILY SSF50249 65 186 2.29E-29 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold TK1169 a97651778fed7ce0b949feb8bcdb162f 198 Gene3D G3DSA:2.40.50.140 66 155 3.8E-24 T 31-10-2018 TK1169 a97651778fed7ce0b949feb8bcdb162f 198 Gene3D G3DSA:2.20.70.10 156 189 2.0E-17 T 31-10-2018 TK1169 a97651778fed7ce0b949feb8bcdb162f 198 SUPERFAMILY SSF110324 11 63 2.93E-12 T 31-10-2018 TK1169 a97651778fed7ce0b949feb8bcdb162f 198 Pfam PF14382 Exosome complex exonuclease RRP4 N-terminal region 12 48 6.7E-9 T 31-10-2018 IPR025721 Exosome complex component, N-terminal domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TK1169 a97651778fed7ce0b949feb8bcdb162f 198 Gene3D G3DSA:2.40.50.100 11 61 7.0E-18 T 31-10-2018 TK1169 a97651778fed7ce0b949feb8bcdb162f 198 Pfam PF10447 Exosome component EXOSC1/CSL4 66 123 9.7E-6 T 31-10-2018 IPR019495 Exosome complex component CSL4, C-terminal GO:0000178|GO:0003723 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TK0718 0fb6c9ebff48067d14ffea37d1c48350 265 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 68 256 1.7E-23 T 31-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TK0718 0fb6c9ebff48067d14ffea37d1c48350 265 TIGRFAM TIGR01581 Mo_ABC_porter: NifC-like ABC-type porter 33 250 1.3E-79 T 31-10-2018 IPR006469 NifC-like ABC-type porter GO:0005215|GO:0016020|GO:0055085 TK0718 0fb6c9ebff48067d14ffea37d1c48350 265 Gene3D G3DSA:1.10.3720.10 5 262 6.7E-62 T 31-10-2018 IPR035906 MetI-like superfamily TK0718 0fb6c9ebff48067d14ffea37d1c48350 265 SUPERFAMILY SSF161098 12 255 3.01E-51 T 31-10-2018 IPR035906 MetI-like superfamily TK1671 f9350033aeb73236b22ff4b2977761aa 333 Pfam PF08608 Wyosine base formation 255 315 1.3E-22 T 31-10-2018 IPR013917 tRNA wybutosine-synthesis MetaCyc: PWY-7285|MetaCyc: PWY-7286 TK1671 f9350033aeb73236b22ff4b2977761aa 333 SUPERFAMILY SSF102114 71 281 2.75E-17 T 31-10-2018 TK1671 f9350033aeb73236b22ff4b2977761aa 333 Hamap MF_01921 S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase [taw1]. 15 316 50.188 T 31-10-2018 IPR023993 S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase, archaea GO:0008033|GO:0016829|GO:0051539 MetaCyc: PWY-7285|MetaCyc: PWY-7286 TK1671 f9350033aeb73236b22ff4b2977761aa 333 Gene3D G3DSA:3.20.20.70 3 333 3.3E-135 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TK1671 f9350033aeb73236b22ff4b2977761aa 333 Pfam PF04055 Radical SAM superfamily 67 252 8.4E-26 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TK1671 f9350033aeb73236b22ff4b2977761aa 333 TIGRFAM TIGR03972 rSAM_TYW1: wyosine biosynthesis protein TYW1 16 314 4.8E-131 T 31-10-2018 IPR023993 S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase, archaea GO:0008033|GO:0016829|GO:0051539 MetaCyc: PWY-7285|MetaCyc: PWY-7286 TK1064 8d906c809c568d6ba94a9ab328bc9685 383 Pfam PF13186 Iron-sulfur cluster-binding domain 260 338 4.4E-17 T 31-10-2018 IPR023885 4Fe4S-binding SPASM domain TK1064 8d906c809c568d6ba94a9ab328bc9685 383 SMART SM00729 29 225 0.0046 T 31-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TK1064 8d906c809c568d6ba94a9ab328bc9685 383 Pfam PF13394 4Fe-4S single cluster domain 35 121 6.2E-7 T 31-10-2018 TK1064 8d906c809c568d6ba94a9ab328bc9685 383 PIRSF PIRSF037420 290 371 5.1E-7 T 31-10-2018 IPR017200 Coenzyme PQQ synthesis protein E TK1064 8d906c809c568d6ba94a9ab328bc9685 383 PIRSF PIRSF037420 22 214 1.4E-25 T 31-10-2018 IPR017200 Coenzyme PQQ synthesis protein E TK1064 8d906c809c568d6ba94a9ab328bc9685 383 TIGRFAM TIGR04317 W_rSAM_matur: tungsten cofactor oxidoreducase radical SAM maturase 27 373 2.0E-154 T 31-10-2018 IPR027604 Tungsten cofactor oxidoreducase radical SAM maturase TK1064 8d906c809c568d6ba94a9ab328bc9685 383 Pfam PF04055 Radical SAM superfamily 33 198 6.0E-17 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TK1064 8d906c809c568d6ba94a9ab328bc9685 383 SUPERFAMILY SSF102114 30 343 4.05E-55 T 31-10-2018 TK0582 85fa0aef10e32b8f8d610d732cae0b21 253 Hamap MF_00317 DNA polymerase sliding clamp [pcn]. 3 248 26.862 T 31-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 TK0582 85fa0aef10e32b8f8d610d732cae0b21 253 SUPERFAMILY SSF55979 3 124 1.35E-25 T 31-10-2018 TK0582 85fa0aef10e32b8f8d610d732cae0b21 253 SUPERFAMILY SSF55979 124 250 1.28E-24 T 31-10-2018 TK0582 85fa0aef10e32b8f8d610d732cae0b21 253 Gene3D G3DSA:3.70.10.10 1 252 7.1E-66 T 31-10-2018 TK0582 85fa0aef10e32b8f8d610d732cae0b21 253 Pfam PF02747 Proliferating cell nuclear antigen, C-terminal domain 139 246 7.0E-7 T 31-10-2018 IPR022649 Proliferating cell nuclear antigen, PCNA, C-terminal GO:0003677|GO:0006275 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 TK0582 85fa0aef10e32b8f8d610d732cae0b21 253 ProSitePatterns PS01251 Proliferating cell nuclear antigen signature 1. 35 58 - T 31-10-2018 IPR022659 Proliferating cell nuclear antigen, PCNA, conserved site Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 TK0582 85fa0aef10e32b8f8d610d732cae0b21 253 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 234 251 3.4E-10 T 31-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 TK0582 85fa0aef10e32b8f8d610d732cae0b21 253 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 35 53 3.4E-10 T 31-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 TK0582 85fa0aef10e32b8f8d610d732cae0b21 253 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 57 81 3.4E-10 T 31-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 TK0582 85fa0aef10e32b8f8d610d732cae0b21 253 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 107 129 3.4E-10 T 31-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 TK0582 85fa0aef10e32b8f8d610d732cae0b21 253 Pfam PF00705 Proliferating cell nuclear antigen, N-terminal domain 3 93 1.8E-13 T 31-10-2018 IPR022648 Proliferating cell nuclear antigen, PCNA, N-terminal GO:0003677|GO:0006275 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 TK2228 5c07eb6e77ff47374f12326715c38a16 128 SMART SM00670 3 117 0.0017 T 31-10-2018 IPR002716 PIN domain TK2228 5c07eb6e77ff47374f12326715c38a16 128 SUPERFAMILY SSF88723 3 118 4.49E-20 T 31-10-2018 IPR029060 PIN-like domain superfamily TK2228 5c07eb6e77ff47374f12326715c38a16 128 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 2 126 10.865 T 31-10-2018 IPR022907 VapC family GO:0004540 TK2228 5c07eb6e77ff47374f12326715c38a16 128 Gene3D G3DSA:3.40.50.1010 2 127 2.9E-15 T 31-10-2018 TK2228 5c07eb6e77ff47374f12326715c38a16 128 Pfam PF01850 PIN domain 3 117 2.5E-17 T 31-10-2018 IPR002716 PIN domain TK0994 d77f42375965592302fa9d0d97d200df 331 TIGRFAM TIGR00345 GET3_arsA_TRC40: transport-energizing ATPase, TRC40/GET3/ArsA family 15 323 3.8E-75 T 31-10-2018 IPR016300 Arsenical pump ATPase, ArsA/GET3 GO:0005524|GO:0016887 Reactome: R-HSA-381038 TK0994 d77f42375965592302fa9d0d97d200df 331 Gene3D G3DSA:3.40.50.300 4 331 1.2E-87 T 31-10-2018 TK0994 d77f42375965592302fa9d0d97d200df 331 SUPERFAMILY SSF52540 10 322 2.97E-43 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK0994 d77f42375965592302fa9d0d97d200df 331 Pfam PF02374 Anion-transporting ATPase 12 327 1.2E-73 T 31-10-2018 IPR025723 Anion-transporting ATPase-like domain Reactome: R-HSA-381038 TK1551 3ca342209908802da1ba32e735e88bdd 276 Pfam PF01171 PP-loop family 55 160 1.0E-7 T 31-10-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 TK1551 3ca342209908802da1ba32e735e88bdd 276 Gene3D G3DSA:3.40.50.620 2 184 3.5E-30 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TK1551 3ca342209908802da1ba32e735e88bdd 276 PIRSF PIRSF036668 1 274 3.1E-126 T 31-10-2018 IPR012121 ATPase, PP-loop, MJ1599-related TK1551 3ca342209908802da1ba32e735e88bdd 276 SUPERFAMILY SSF52402 28 203 4.85E-31 T 31-10-2018 TK0208 264bba6fabc6e13ec23898754d067ee0 334 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 2 320 4.0E-125 T 31-10-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TK0208 264bba6fabc6e13ec23898754d067ee0 334 Gene3D G3DSA:3.90.650.10 166 332 6.6E-50 T 31-10-2018 IPR036676 PurM-like, C-terminal domain superfamily TK0208 264bba6fabc6e13ec23898754d067ee0 334 Pfam PF00586 AIR synthase related protein, N-terminal domain 57 159 2.6E-19 T 31-10-2018 IPR016188 PurM-like, N-terminal domain TK0208 264bba6fabc6e13ec23898754d067ee0 334 SUPERFAMILY SSF56042 166 327 2.99E-43 T 31-10-2018 IPR036676 PurM-like, C-terminal domain superfamily TK0208 264bba6fabc6e13ec23898754d067ee0 334 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 2 330 37.664 T 31-10-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TK0208 264bba6fabc6e13ec23898754d067ee0 334 Pfam PF02769 AIR synthase related protein, C-terminal domain 171 327 5.9E-26 T 31-10-2018 IPR010918 PurM-like, C-terminal domain TK0208 264bba6fabc6e13ec23898754d067ee0 334 SUPERFAMILY SSF55326 2 165 1.94E-40 T 31-10-2018 IPR036921 PurM-like, N-terminal domain superfamily TK0208 264bba6fabc6e13ec23898754d067ee0 334 Gene3D G3DSA:3.30.1330.10 2 165 7.8E-52 T 31-10-2018 IPR036921 PurM-like, N-terminal domain superfamily TK1381 999e230a2772d9fb9cdbf87584329bc5 431 SUPERFAMILY SSF48537 30 265 2.62E-44 T 31-10-2018 IPR008947 Phospholipase C/P1 nuclease domain superfamily GO:0016788 TK1381 999e230a2772d9fb9cdbf87584329bc5 431 Pfam PF00882 Zinc dependent phospholipase C 36 185 3.6E-6 T 31-10-2018 IPR029002 Phospholipase C/D Reactome: R-HSA-163125 TK1381 999e230a2772d9fb9cdbf87584329bc5 431 Gene3D G3DSA:1.10.575.10 23 181 2.3E-12 T 31-10-2018 IPR008947 Phospholipase C/P1 nuclease domain superfamily GO:0016788 TK1381 999e230a2772d9fb9cdbf87584329bc5 431 SMART SM00770 1 256 1.1E-88 T 31-10-2018 IPR001531 Zinc-dependent phospholipase C GO:0004629|GO:0008270 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 TK1419 73f5277e5cacb73ab9fa5145e0e08a2e 152 Hamap MF_00950 Transcription elongation factor Spt5 [spt5]. 5 148 38.293 T 31-10-2018 IPR011590 Transcription elongation factor Spt5, archaeal GO:0003746 TK1419 73f5277e5cacb73ab9fa5145e0e08a2e 152 Gene3D G3DSA:2.30.30.30 88 152 2.7E-28 T 31-10-2018 IPR014722 Ribosomal protein L2, domain 2 TK1419 73f5277e5cacb73ab9fa5145e0e08a2e 152 Pfam PF00467 KOW motif 95 126 6.9E-9 T 31-10-2018 IPR005824 KOW TK1419 73f5277e5cacb73ab9fa5145e0e08a2e 152 Gene3D G3DSA:3.30.70.940 2 87 7.2E-32 T 31-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 TK1419 73f5277e5cacb73ab9fa5145e0e08a2e 152 SMART SM00739 92 119 3.1E-7 T 31-10-2018 IPR005824 KOW TK1419 73f5277e5cacb73ab9fa5145e0e08a2e 152 SMART SM00738 3 87 4.4E-18 T 31-10-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 TK1419 73f5277e5cacb73ab9fa5145e0e08a2e 152 SUPERFAMILY SSF50104 54 147 2.07E-18 T 31-10-2018 IPR008991 Translation protein SH3-like domain superfamily TK1419 73f5277e5cacb73ab9fa5145e0e08a2e 152 Pfam PF03439 Early transcription elongation factor of RNA pol II, NGN section 5 84 4.8E-23 T 31-10-2018 IPR005100 NGN domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 TK1419 73f5277e5cacb73ab9fa5145e0e08a2e 152 TIGRFAM TIGR00405 KOW_elon_Spt5: transcription elongation factor Spt5 7 150 6.9E-51 T 31-10-2018 IPR011590 Transcription elongation factor Spt5, archaeal GO:0003746 TK0870 92641f1325062a0ded5820ca79355d2b 245 Gene3D G3DSA:3.30.1360.170 1 202 1.1E-62 T 31-10-2018 TK0870 92641f1325062a0ded5820ca79355d2b 245 Hamap MF_01408 Flavin-dependent thymidylate synthase [thyX]. 1 219 30.912 T 31-10-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 TK0870 92641f1325062a0ded5820ca79355d2b 245 SUPERFAMILY SSF69796 5 198 1.12E-59 T 31-10-2018 IPR036098 Thymidylate synthase ThyX superfamily GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 TK0870 92641f1325062a0ded5820ca79355d2b 245 Pfam PF02511 Thymidylate synthase complementing protein 8 198 2.1E-62 T 31-10-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 TK0870 92641f1325062a0ded5820ca79355d2b 245 TIGRFAM TIGR02170 thyX: thymidylate synthase, flavin-dependent 6 198 5.0E-53 T 31-10-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 TK0842 a76ac98b61abea2574895075efcbf36e 365 Gene3D G3DSA:1.20.1530.20 3 344 1.0E-22 T 31-10-2018 IPR038770 Sodium/solute symporter superfamily TK0842 a76ac98b61abea2574895075efcbf36e 365 Pfam PF01758 Sodium Bile acid symporter family 53 254 3.1E-46 T 31-10-2018 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 TK0842 a76ac98b61abea2574895075efcbf36e 365 TIGRFAM TIGR00832 acr3: arsenical-resistance protein 7 342 2.1E-117 T 31-10-2018 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 TK0842 a76ac98b61abea2574895075efcbf36e 365 PIRSF PIRSF005508 1 358 4.6E-140 T 31-10-2018 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 TK0126 ab8c51a256904ce5ca38eac81210629f 180 Gene3D G3DSA:1.10.260.40 80 180 3.0E-11 T 31-10-2018 TK0126 ab8c51a256904ce5ca38eac81210629f 180 SUPERFAMILY SSF47413 81 144 2.79E-7 T 31-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TK0126 ab8c51a256904ce5ca38eac81210629f 180 SMART SM00530 91 146 2.2E-5 T 31-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TK0126 ab8c51a256904ce5ca38eac81210629f 180 TIGRFAM TIGR00270 TIGR00270: TIGR00270 family protein 8 173 1.4E-21 T 31-10-2018 IPR004451 Conserved hypothetical protein CHP00270 TK0126 ab8c51a256904ce5ca38eac81210629f 180 Pfam PF01381 Helix-turn-helix 96 143 2.9E-6 T 31-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TK1796 5d1a83fa8c3f500baee8b12dfde1cea2 443 Pfam PF00120 Glutamine synthetase, catalytic domain 101 440 7.7E-128 T 31-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 TK1796 5d1a83fa8c3f500baee8b12dfde1cea2 443 ProSitePatterns PS00180 Glutamine synthetase signature 1. 52 70 - T 31-10-2018 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 TK1796 5d1a83fa8c3f500baee8b12dfde1cea2 443 SUPERFAMILY SSF55931 101 441 6.08E-123 T 31-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 TK1796 5d1a83fa8c3f500baee8b12dfde1cea2 443 Gene3D G3DSA:3.30.590.10 103 442 2.3E-127 T 31-10-2018 TK1796 5d1a83fa8c3f500baee8b12dfde1cea2 443 SMART SM01230 100 343 9.6E-134 T 31-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 TK1796 5d1a83fa8c3f500baee8b12dfde1cea2 443 SUPERFAMILY SSF54368 19 84 1.83E-17 T 31-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 TK1796 5d1a83fa8c3f500baee8b12dfde1cea2 443 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 19 84 3.7E-20 T 31-10-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 TK1796 5d1a83fa8c3f500baee8b12dfde1cea2 443 Gene3D G3DSA:3.10.20.70 9 102 8.0E-22 T 31-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 TK1796 5d1a83fa8c3f500baee8b12dfde1cea2 443 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 226 241 - T 31-10-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 TK1796 5d1a83fa8c3f500baee8b12dfde1cea2 443 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 136 441 9.5E-136 T 31-10-2018 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 TK1172 1a601ac2d88ba6dfedb82b70eee7d660 224 Gene3D G3DSA:3.40.1350.70 1 98 2.5E-61 T 31-10-2018 IPR038230 TBP-interacting protein, N-terminal superfamily TK1172 1a601ac2d88ba6dfedb82b70eee7d660 224 SUPERFAMILY SSF159612 1 217 5.89E-114 T 31-10-2018 TK1172 1a601ac2d88ba6dfedb82b70eee7d660 224 Pfam PF15517 TBP-interacting protein N-terminus 2 100 2.3E-50 T 31-10-2018 IPR029125 TBP-interacting protein, N-terminal TK1172 1a601ac2d88ba6dfedb82b70eee7d660 224 Gene3D G3DSA:3.90.79.30 99 218 2.4E-75 T 31-10-2018 TK1764 d67f4ddeb36c8f9b864ee01899623216 267 Gene3D G3DSA:3.40.50.10320 1 267 5.6E-95 T 31-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 TK1764 d67f4ddeb36c8f9b864ee01899623216 267 SUPERFAMILY SSF102588 32 255 1.1E-55 T 31-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 TK1764 d67f4ddeb36c8f9b864ee01899623216 267 Pfam PF02585 GlcNAc-PI de-N-acetylase 35 161 2.3E-26 T 31-10-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 TK1710 1eeef3abe782500d55cee634097fa77f 143 Pfam PF01934 Protein of unknown function DUF86 18 134 1.4E-31 T 31-10-2018 IPR008201 Protein of unknown function DUF86 TK1710 1eeef3abe782500d55cee634097fa77f 143 Gene3D G3DSA:1.20.120.580 4 142 3.8E-26 T 31-10-2018 IPR037038 Bsu32300-like superfamily TK1710 1eeef3abe782500d55cee634097fa77f 143 SUPERFAMILY SSF81593 69 135 8.63E-5 T 31-10-2018 TK0161 b49aa7203c966fab138d250bc6c9ae18 220 SUPERFAMILY SSF52540 2 216 1.88E-47 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK0161 b49aa7203c966fab138d250bc6c9ae18 220 Gene3D G3DSA:3.40.50.300 1 218 8.7E-50 T 31-10-2018 TK0161 b49aa7203c966fab138d250bc6c9ae18 220 ProSitePatterns PS00211 ABC transporters family signature. 127 141 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TK0161 b49aa7203c966fab138d250bc6c9ae18 220 SMART SM00382 25 218 4.3E-5 T 31-10-2018 IPR003593 AAA+ ATPase domain TK0161 b49aa7203c966fab138d250bc6c9ae18 220 Pfam PF00005 ABC transporter 17 155 2.1E-21 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TK0252 4cd6658dd7754727a35c53d2a779e7b4 227 Pfam PF00218 Indole-3-glycerol phosphate synthase 6 222 1.1E-58 T 31-10-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 TK0252 4cd6658dd7754727a35c53d2a779e7b4 227 SUPERFAMILY SSF51366 3 223 1.41E-62 T 31-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 TK0252 4cd6658dd7754727a35c53d2a779e7b4 227 ProSitePatterns PS00614 Indole-3-glycerol phosphate synthase signature. 17 32 - T 31-10-2018 IPR001468 Indole-3-glycerol phosphate synthase, conserved site GO:0004425|GO:0006568 KEGG: 00400+4.1.1.48 TK0252 4cd6658dd7754727a35c53d2a779e7b4 227 Gene3D G3DSA:3.20.20.70 2 227 2.5E-73 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TK0252 4cd6658dd7754727a35c53d2a779e7b4 227 Hamap MF_00134_A Indole-3-glycerol phosphate synthase [trpC]. 2 220 31.463 T 31-10-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 TK1620 578ceeaa23807819642b1504eac75138 1157 Pfam PF00493 MCM2/3/5 family 887 1067 2.0E-65 T 31-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 TK1620 578ceeaa23807819642b1504eac75138 1157 Pfam PF00493 MCM2/3/5 family 266 365 8.5E-37 T 31-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 TK1620 578ceeaa23807819642b1504eac75138 1157 Pfam PF00493 MCM2/3/5 family 503 554 1.1E-18 T 31-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 TK1620 578ceeaa23807819642b1504eac75138 1157 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 867 889 1.1E-4 T 31-10-2018 IPR030934 Intein C-terminal splicing region TK1620 578ceeaa23807819642b1504eac75138 1157 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 481 503 4.0E-10 T 31-10-2018 IPR030934 Intein C-terminal splicing region TK1620 578ceeaa23807819642b1504eac75138 1157 Gene3D G3DSA:2.170.16.10 468 500 8.8E-6 T 31-10-2018 TK1620 578ceeaa23807819642b1504eac75138 1157 Gene3D G3DSA:3.40.50.300 263 385 3.9E-39 T 31-10-2018 TK1620 578ceeaa23807819642b1504eac75138 1157 Gene3D G3DSA:3.40.50.300 874 1071 5.1E-69 T 31-10-2018 TK1620 578ceeaa23807819642b1504eac75138 1157 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 320 335 4.1E-9 T 31-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 TK1620 578ceeaa23807819642b1504eac75138 1157 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 520 534 4.1E-9 T 31-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 TK1620 578ceeaa23807819642b1504eac75138 1157 Gene3D G3DSA:2.20.28.10 132 177 2.7E-29 T 31-10-2018 TK1620 578ceeaa23807819642b1504eac75138 1157 TIGRFAM TIGR01445 intein_Nterm: intein N-terminal splicing region 560 650 2.2E-15 T 31-10-2018 IPR006141 Intein N-terminal splicing region GO:0016539 Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TK1620 578ceeaa23807819642b1504eac75138 1157 TIGRFAM TIGR01445 intein_Nterm: intein N-terminal splicing region 363 447 2.6E-8 T 31-10-2018 IPR006141 Intein N-terminal splicing region GO:0016539 Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TK1620 578ceeaa23807819642b1504eac75138 1157 Gene3D G3DSA:2.40.50.140 178 257 2.0E-26 T 31-10-2018 TK1620 578ceeaa23807819642b1504eac75138 1157 Pfam PF14890 Intein splicing domain 562 888 8.9E-23 T 31-10-2018 TK1620 578ceeaa23807819642b1504eac75138 1157 Gene3D G3DSA:3.40.50.300 501 559 5.3E-20 T 31-10-2018 TK1620 578ceeaa23807819642b1504eac75138 1157 Gene3D G3DSA:1.10.10.10 1072 1157 1.2E-23 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TK1620 578ceeaa23807819642b1504eac75138 1157 SUPERFAMILY SSF51294 556 888 2.16E-32 T 31-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TK1620 578ceeaa23807819642b1504eac75138 1157 Gene3D G3DSA:2.170.16.10 560 706 5.4E-36 T 31-10-2018 TK1620 578ceeaa23807819642b1504eac75138 1157 SUPERFAMILY SSF50249 10 248 3.94E-63 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold TK1620 578ceeaa23807819642b1504eac75138 1157 Gene3D G3DSA:3.30.1640.10 1 100 2.0E-37 T 31-10-2018 TK1620 578ceeaa23807819642b1504eac75138 1157 SUPERFAMILY SSF52540 886 1064 5.44E-22 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK1620 578ceeaa23807819642b1504eac75138 1157 SMART SM00350 101 1068 1.4E-72 T 31-10-2018 IPR031327 Mini-chromosome maintenance protein TK1620 578ceeaa23807819642b1504eac75138 1157 Pfam PF17207 MCM OB domain 105 230 1.7E-35 T 31-10-2018 IPR033762 MCM OB domain Reactome: R-HSA-176187|Reactome: R-HSA-176974|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962 TK1620 578ceeaa23807819642b1504eac75138 1157 SUPERFAMILY SSF51294 363 503 6.02E-22 T 31-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TK1620 578ceeaa23807819642b1504eac75138 1157 SMART SM00306 361 464 2.2E-9 T 31-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TK1620 578ceeaa23807819642b1504eac75138 1157 SMART SM00306 552 674 3.7E-20 T 31-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TK1620 578ceeaa23807819642b1504eac75138 1157 Pfam PF14551 MCM N-terminal domain 9 82 8.3E-13 T 31-10-2018 IPR027925 MCM N-terminal domain Reactome: R-HSA-176187|Reactome: R-HSA-176974|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962|Reactome: R-HSA-69052 TK1620 578ceeaa23807819642b1504eac75138 1157 SMART SM00305 462 508 1.4E-10 T 31-10-2018 IPR003586 Hint domain C-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TK1620 578ceeaa23807819642b1504eac75138 1157 SMART SM00305 846 894 3.8E-5 T 31-10-2018 IPR003586 Hint domain C-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TK1620 578ceeaa23807819642b1504eac75138 1157 SUPERFAMILY SSF52540 290 567 3.8E-18 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK0249 28ca75d0d72a1019dcd9f2a8520c626c 209 Hamap MF_01020 Phosphoribosyl-ATP pyrophosphatase [hisE]. 121 204 19.246 T 31-10-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 TK0249 28ca75d0d72a1019dcd9f2a8520c626c 209 SUPERFAMILY SSF141734 4 114 1.7E-42 T 31-10-2018 IPR038019 Phosphoribosyl-AMP cyclohydrolase domain superfamily KEGG: 00340+3.5.4.19 TK0249 28ca75d0d72a1019dcd9f2a8520c626c 209 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 33 105 3.9E-31 T 31-10-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 TK0249 28ca75d0d72a1019dcd9f2a8520c626c 209 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 124 207 1.9E-15 T 31-10-2018 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 TK0249 28ca75d0d72a1019dcd9f2a8520c626c 209 Gene3D G3DSA:3.10.20.400 2 96 2.5E-34 T 31-10-2018 IPR038019 Phosphoribosyl-AMP cyclohydrolase domain superfamily KEGG: 00340+3.5.4.19 TK0249 28ca75d0d72a1019dcd9f2a8520c626c 209 Gene3D G3DSA:1.10.287.1080 121 209 7.7E-27 T 31-10-2018 TK0249 28ca75d0d72a1019dcd9f2a8520c626c 209 TIGRFAM TIGR03188 histidine_hisI: phosphoribosyl-ATP diphosphatase 124 204 1.4E-28 T 31-10-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 TK0249 28ca75d0d72a1019dcd9f2a8520c626c 209 Hamap MF_01021 Phosphoribosyl-AMP cyclohydrolase [hisI]. 7 109 28.761 T 31-10-2018 IPR026660 Phosphoribosyl-AMP cyclohydrolase GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 TK0249 28ca75d0d72a1019dcd9f2a8520c626c 209 Hamap MF_01019 Histidine biosynthesis bifunctional protein HisIE [hisI]. 8 209 36.519 T 31-10-2018 IPR023019 Histidine biosynthesis bifunctional protein HisIE GO:0000105|GO:0004635|GO:0004636 KEGG: 00340+3.6.1.31+3.5.4.19 TK0249 28ca75d0d72a1019dcd9f2a8520c626c 209 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 55 108 5.0E-26 T 31-10-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 TK0249 28ca75d0d72a1019dcd9f2a8520c626c 209 SUPERFAMILY SSF101386 123 208 2.99E-22 T 31-10-2018 TK1151 866d18f8593f720789f8b7965132fe89 255 Pfam PF12679 ABC-2 family transporter protein 2 192 8.8E-15 T 31-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 TK2217 496886a0b83b018f3f867b89d615d304 395 Pfam PF00155 Aminotransferase class I and II 39 383 9.5E-70 T 31-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 TK2217 496886a0b83b018f3f867b89d615d304 395 Gene3D G3DSA:3.40.640.10 55 291 7.8E-140 T 31-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TK2217 496886a0b83b018f3f867b89d615d304 395 Gene3D G3DSA:3.90.1150.10 35 385 7.8E-140 T 31-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TK2217 496886a0b83b018f3f867b89d615d304 395 TIGRFAM TIGR01825 gly_Cac_T_rel: putative pyridoxal phosphate-dependent acyltransferase 7 394 1.3E-200 T 31-10-2018 IPR010962 Putative 8-amino-7-oxononanoate synthase, Archaea/Firmicutes type TK2217 496886a0b83b018f3f867b89d615d304 395 SUPERFAMILY SSF53383 4 391 2.39E-118 T 31-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TK2217 496886a0b83b018f3f867b89d615d304 395 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 238 247 - T 31-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 TK1063 3ce858ee774b5d446d169a8b7e38df5d 270 SUPERFAMILY SSF82861 16 100 6.8E-10 T 31-10-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 TK1063 3ce858ee774b5d446d169a8b7e38df5d 270 Pfam PF00924 Mechanosensitive ion channel 60 256 1.5E-49 T 31-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 TK1063 3ce858ee774b5d446d169a8b7e38df5d 270 SUPERFAMILY SSF50182 101 167 4.9E-15 T 31-10-2018 IPR010920 LSM domain superfamily TK1063 3ce858ee774b5d446d169a8b7e38df5d 270 SUPERFAMILY SSF82689 168 266 6.15E-36 T 31-10-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 TK1063 3ce858ee774b5d446d169a8b7e38df5d 270 Gene3D G3DSA:3.30.70.100 167 261 2.1E-33 T 31-10-2018 TK1063 3ce858ee774b5d446d169a8b7e38df5d 270 Pfam PF05552 Conserved TM helix 17 48 1.5E-6 T 31-10-2018 IPR008910 Conserved TM helix TK1063 3ce858ee774b5d446d169a8b7e38df5d 270 Gene3D G3DSA:2.30.30.60 117 166 3.1E-15 T 31-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily TK0297 235af00bacc72ac86f49cb687a4ab15a 466 SUPERFAMILY SSF51905 6 364 2.57E-47 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TK0297 235af00bacc72ac86f49cb687a4ab15a 466 SUPERFAMILY SSF46977 386 453 6.02E-19 T 31-10-2018 IPR037099 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 TK0297 235af00bacc72ac86f49cb687a4ab15a 466 Pfam PF00890 FAD binding domain 6 348 1.0E-65 T 31-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 TK0297 235af00bacc72ac86f49cb687a4ab15a 466 Pfam PF02910 Fumarate reductase flavoprotein C-term 428 449 7.7E-6 T 31-10-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 TK0297 235af00bacc72ac86f49cb687a4ab15a 466 Gene3D G3DSA:3.90.700.10 213 303 3.0E-109 T 31-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 TK0297 235af00bacc72ac86f49cb687a4ab15a 466 TIGRFAM TIGR00551 nadB: L-aspartate oxidase 3 448 2.4E-152 T 31-10-2018 IPR005288 L-aspartate oxidase GO:0005737|GO:0008734|GO:0009435|GO:0055114 KEGG: 00250+1.4.3.16|KEGG: 00760+1.4.3.16|MetaCyc: PWY-5316|MetaCyc: PWY-7342 TK0297 235af00bacc72ac86f49cb687a4ab15a 466 Gene3D G3DSA:1.20.58.100 370 462 1.4E-18 T 31-10-2018 TK0297 235af00bacc72ac86f49cb687a4ab15a 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 167 176 9.3E-6 T 31-10-2018 TK0297 235af00bacc72ac86f49cb687a4ab15a 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 326 333 9.3E-6 T 31-10-2018 TK0297 235af00bacc72ac86f49cb687a4ab15a 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 3 25 9.3E-6 T 31-10-2018 TK0297 235af00bacc72ac86f49cb687a4ab15a 466 SUPERFAMILY SSF56425 205 309 3.89E-32 T 31-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 TK0297 235af00bacc72ac86f49cb687a4ab15a 466 Gene3D G3DSA:3.50.50.60 6 355 3.0E-109 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TK0297 235af00bacc72ac86f49cb687a4ab15a 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 1.0E-8 T 31-10-2018 TK0297 235af00bacc72ac86f49cb687a4ab15a 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 311 333 1.0E-8 T 31-10-2018 TK1548 047b747761af0a5b1afda8ec56157baa 385 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 202 222 - T 31-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site TK1548 047b747761af0a5b1afda8ec56157baa 385 SUPERFAMILY SSF53383 11 383 1.11E-95 T 31-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TK1548 047b747761af0a5b1afda8ec56157baa 385 Pfam PF00266 Aminotransferase class-V 45 369 1.4E-40 T 31-10-2018 IPR000192 Aminotransferase class V domain TK1548 047b747761af0a5b1afda8ec56157baa 385 Gene3D G3DSA:3.90.1150.10 25 379 2.6E-136 T 31-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TK1548 047b747761af0a5b1afda8ec56157baa 385 Gene3D G3DSA:3.40.640.10 35 280 2.6E-136 T 31-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TK1548 047b747761af0a5b1afda8ec56157baa 385 PIRSF PIRSF000524 17 385 6.8E-101 T 31-10-2018 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832|Reactome: R-HSA-389661|Reactome: R-HSA-9033241 TK2215 43280c329692d45c6c80c17e8c7480b3 168 Pfam PF02778 tRNA intron endonuclease, N-terminal domain 3 67 2.6E-21 T 31-10-2018 IPR006678 tRNA intron endonuclease, N-terminal GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803|Reactome: R-HSA-6784531 TK2215 43280c329692d45c6c80c17e8c7480b3 168 SUPERFAMILY SSF55267 2 73 1.94E-19 T 31-10-2018 IPR036740 tRNA intron endonuclease, N-terminal domain superfamily GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803 TK2215 43280c329692d45c6c80c17e8c7480b3 168 Gene3D G3DSA:3.40.1350.10 76 168 1.7E-34 T 31-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 TK2215 43280c329692d45c6c80c17e8c7480b3 168 Hamap MF_01833 tRNA-splicing endonuclease [endA]. 2 168 34.119 T 31-10-2018 IPR016442 tRNA-splicing endonuclease, archaeal short subfamily MetaCyc: PWY-6689|MetaCyc: PWY-7803 TK2215 43280c329692d45c6c80c17e8c7480b3 168 SUPERFAMILY SSF53032 77 166 3.4E-31 T 31-10-2018 IPR036167 tRNA intron endonuclease, catalytic domain-like superfamily GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803|Reactome: R-HSA-6784531 TK2215 43280c329692d45c6c80c17e8c7480b3 168 TIGRFAM TIGR00324 endA: tRNA-intron lyase 6 166 5.5E-41 T 31-10-2018 IPR006676 tRNA-splicing endonuclease GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803|Reactome: R-HSA-6784531 TK2215 43280c329692d45c6c80c17e8c7480b3 168 Gene3D G3DSA:3.40.1170.20 5 70 5.2E-18 T 31-10-2018 TK2215 43280c329692d45c6c80c17e8c7480b3 168 PIRSF PIRSF005285 5 168 8.2E-69 T 31-10-2018 IPR016442 tRNA-splicing endonuclease, archaeal short subfamily MetaCyc: PWY-6689|MetaCyc: PWY-7803 TK2215 43280c329692d45c6c80c17e8c7480b3 168 Pfam PF01974 tRNA intron endonuclease, catalytic C-terminal domain 77 160 3.4E-33 T 31-10-2018 IPR006677 tRNA intron endonuclease, catalytic domain-like GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803|Reactome: R-HSA-6784531 TK1500 fb5f438adf554ca6cd79f843b726b4e0 135 TIGRFAM TIGR03627 uS9_arch: ribosomal protein uS9 3 135 9.9E-62 T 31-10-2018 IPR019958 Ribosomal protein S9, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 TK1500 fb5f438adf554ca6cd79f843b726b4e0 135 Hamap MF_00532_A 30S ribosomal protein S9 [rpsI]. 3 135 37.216 T 31-10-2018 IPR019958 Ribosomal protein S9, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 TK1500 fb5f438adf554ca6cd79f843b726b4e0 135 Pfam PF00380 Ribosomal protein S9/S16 8 135 1.7E-30 T 31-10-2018 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 TK1500 fb5f438adf554ca6cd79f843b726b4e0 135 SUPERFAMILY SSF54211 3 135 9.48E-34 T 31-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TK1500 fb5f438adf554ca6cd79f843b726b4e0 135 ProSitePatterns PS00360 Ribosomal protein S9 signature. 68 86 - T 31-10-2018 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 TK1500 fb5f438adf554ca6cd79f843b726b4e0 135 Gene3D G3DSA:3.30.230.10 1 135 8.6E-51 T 31-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TK0702 eba3c22bb1679093b2aec5295ec4e08d 310 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 120 131 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TK0702 eba3c22bb1679093b2aec5295ec4e08d 310 SUPERFAMILY SSF52540 22 306 2.55E-32 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK0702 eba3c22bb1679093b2aec5295ec4e08d 310 Gene3D G3DSA:3.30.70.20 82 133 1.9E-9 T 31-10-2018 TK0702 eba3c22bb1679093b2aec5295ec4e08d 310 SUPERFAMILY SSF54862 72 139 2.09E-18 T 31-10-2018 TK0702 eba3c22bb1679093b2aec5295ec4e08d 310 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 23 284 1.5E-19 T 31-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain TK0702 eba3c22bb1679093b2aec5295ec4e08d 310 Pfam PF12837 4Fe-4S binding domain 83 105 3.3E-6 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TK0204 bff7f57313a5d68fe564a66348ded407 431 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 1 416 1.6E-146 T 31-10-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TK0204 bff7f57313a5d68fe564a66348ded407 431 Gene3D G3DSA:3.30.470.20 188 327 2.9E-47 T 31-10-2018 TK0204 bff7f57313a5d68fe564a66348ded407 431 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 1 417 36.188 T 31-10-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TK0204 bff7f57313a5d68fe564a66348ded407 431 ProSitePatterns PS00184 Phosphoribosylglycinamide synthetase signature. 289 296 - T 31-10-2018 IPR020559 Phosphoribosylglycinamide synthetase, conserved site GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TK0204 bff7f57313a5d68fe564a66348ded407 431 Gene3D G3DSA:3.90.600.10 328 417 1.3E-9 T 31-10-2018 IPR037123 Phosphoribosylglycinamide synthetase, C-domain superfamily GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TK0204 bff7f57313a5d68fe564a66348ded407 431 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 329 415 5.1E-13 T 31-10-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TK0204 bff7f57313a5d68fe564a66348ded407 431 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 101 295 2.6E-60 T 31-10-2018 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TK0204 bff7f57313a5d68fe564a66348ded407 431 Gene3D G3DSA:3.40.50.20 2 93 1.2E-21 T 31-10-2018 TK0204 bff7f57313a5d68fe564a66348ded407 431 SUPERFAMILY SSF52440 1 101 2.59E-24 T 31-10-2018 IPR016185 Pre-ATP-grasp domain superfamily TK0204 bff7f57313a5d68fe564a66348ded407 431 Gene3D G3DSA:3.30.1490.20 120 186 2.4E-15 T 31-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 TK0204 bff7f57313a5d68fe564a66348ded407 431 SUPERFAMILY SSF56059 102 321 4.77E-48 T 31-10-2018 TK0204 bff7f57313a5d68fe564a66348ded407 431 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 1 100 8.7E-23 T 31-10-2018 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TK0204 bff7f57313a5d68fe564a66348ded407 431 SUPERFAMILY SSF51246 326 416 2.35E-16 T 31-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 TK0204 bff7f57313a5d68fe564a66348ded407 431 SMART SM01210 327 417 1.1E-20 T 31-10-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TK0204 bff7f57313a5d68fe564a66348ded407 431 SMART SM01209 101 295 6.9E-95 T 31-10-2018 TK1963 3e2b3e5ddb03b281134fb1a716b54e0e 425 SMART SM01274 14 145 2.6E-76 T 31-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 TK1963 3e2b3e5ddb03b281134fb1a716b54e0e 425 SUPERFAMILY SSF51735 157 403 1.11E-82 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily TK1963 3e2b3e5ddb03b281134fb1a716b54e0e 425 SMART SM00919 157 379 4.6E-129 T 31-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 TK1963 3e2b3e5ddb03b281134fb1a716b54e0e 425 SUPERFAMILY SSF53223 11 155 2.01E-51 T 31-10-2018 TK1963 3e2b3e5ddb03b281134fb1a716b54e0e 425 Pfam PF00390 Malic enzyme, N-terminal domain 16 145 5.2E-28 T 31-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 TK1963 3e2b3e5ddb03b281134fb1a716b54e0e 425 Gene3D G3DSA:3.40.50.10380 1 154 5.8E-65 T 31-10-2018 IPR037062 Malic enzyme, N-terminal domain superfamily GO:0004471|GO:0055114 TK1963 3e2b3e5ddb03b281134fb1a716b54e0e 425 Pfam PF03949 Malic enzyme, NAD binding domain 159 360 8.5E-26 T 31-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 TK1963 3e2b3e5ddb03b281134fb1a716b54e0e 425 Gene3D G3DSA:3.40.50.720 155 423 1.2E-91 T 31-10-2018 TK1963 3e2b3e5ddb03b281134fb1a716b54e0e 425 ProSitePatterns PS00331 Malic enzymes signature. 153 169 - T 31-10-2018 IPR015884 Malic enzyme, conserved site GO:0004471|GO:0055114 TK1963 3e2b3e5ddb03b281134fb1a716b54e0e 425 PIRSF PIRSF000106 33 410 8.9E-89 T 31-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 TK0812 fefeca9f50cac8bc128aa57b3769e703 224 Pfam PF05191 Adenylate kinase, active site lid 125 160 1.3E-20 T 31-10-2018 IPR007862 Adenylate kinase, active site lid domain GO:0004017 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 TK0812 fefeca9f50cac8bc128aa57b3769e703 224 PRINTS PR00094 Adenylate kinase signature 79 95 3.6E-27 T 31-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 TK0812 fefeca9f50cac8bc128aa57b3769e703 224 PRINTS PR00094 Adenylate kinase signature 32 46 3.6E-27 T 31-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 TK0812 fefeca9f50cac8bc128aa57b3769e703 224 PRINTS PR00094 Adenylate kinase signature 4 17 3.6E-27 T 31-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 TK0812 fefeca9f50cac8bc128aa57b3769e703 224 PRINTS PR00094 Adenylate kinase signature 158 173 3.6E-27 T 31-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 TK0812 fefeca9f50cac8bc128aa57b3769e703 224 PRINTS PR00094 Adenylate kinase signature 175 189 3.6E-27 T 31-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 TK0812 fefeca9f50cac8bc128aa57b3769e703 224 SUPERFAMILY SSF52540 2 212 2.72E-39 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK0812 fefeca9f50cac8bc128aa57b3769e703 224 ProSitePatterns PS00113 Adenylate kinase signature. 79 90 - T 31-10-2018 IPR033690 Adenylate kinase, conserved site KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 TK0812 fefeca9f50cac8bc128aa57b3769e703 224 TIGRFAM TIGR01351 adk: adenylate kinase 2 210 6.2E-74 T 31-10-2018 IPR006259 Adenylate kinase subfamily GO:0004017|GO:0005524|GO:0016776 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 TK0812 fefeca9f50cac8bc128aa57b3769e703 224 Pfam PF00406 Adenylate kinase 5 188 1.3E-41 T 31-10-2018 TK0812 fefeca9f50cac8bc128aa57b3769e703 224 Hamap MF_00235 Adenylate kinase [adk]. 1 211 45.85 T 31-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 TK0812 fefeca9f50cac8bc128aa57b3769e703 224 Gene3D G3DSA:3.40.50.300 1 219 6.8E-77 T 31-10-2018 TK0016 321a9b320ccf8ce70ba09251a588b9d6 138 SUPERFAMILY SSF88723 1 136 1.01E-23 T 31-10-2018 IPR029060 PIN-like domain superfamily TK0016 321a9b320ccf8ce70ba09251a588b9d6 138 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 2 138 9.857 T 31-10-2018 IPR022907 VapC family GO:0004540 TK0016 321a9b320ccf8ce70ba09251a588b9d6 138 SMART SM00670 1 130 2.5E-6 T 31-10-2018 IPR002716 PIN domain TK0016 321a9b320ccf8ce70ba09251a588b9d6 138 Gene3D G3DSA:3.40.50.1010 2 137 7.9E-22 T 31-10-2018 TK0016 321a9b320ccf8ce70ba09251a588b9d6 138 Pfam PF01850 PIN domain 3 132 2.1E-25 T 31-10-2018 IPR002716 PIN domain TK1579 8779430f93be370639515b4cf1e822db 307 SUPERFAMILY SSF52540 3 225 5.1E-63 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK1579 8779430f93be370639515b4cf1e822db 307 Pfam PF00005 ABC transporter 20 163 1.5E-28 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TK1579 8779430f93be370639515b4cf1e822db 307 SMART SM00382 28 219 2.4E-14 T 31-10-2018 IPR003593 AAA+ ATPase domain TK1579 8779430f93be370639515b4cf1e822db 307 Gene3D G3DSA:3.40.50.300 1 236 2.3E-67 T 31-10-2018 TK1579 8779430f93be370639515b4cf1e822db 307 Pfam PF13732 Domain of unknown function (DUF4162) 216 301 1.3E-7 T 31-10-2018 IPR025302 Domain of unknown function DUF4162 TK1531 b352d33060b3614c1e15fb72f440d6ad 141 Pfam PF00238 Ribosomal protein L14p/L23e 24 140 4.6E-35 T 31-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 TK1531 b352d33060b3614c1e15fb72f440d6ad 141 SMART SM01374 20 141 2.4E-57 T 31-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 TK1531 b352d33060b3614c1e15fb72f440d6ad 141 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 20 141 19.42 T 31-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 TK1531 b352d33060b3614c1e15fb72f440d6ad 141 Gene3D G3DSA:2.40.150.20 1 140 3.3E-49 T 31-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 TK1531 b352d33060b3614c1e15fb72f440d6ad 141 SUPERFAMILY SSF50193 16 141 2.22E-44 T 31-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 TK1531 b352d33060b3614c1e15fb72f440d6ad 141 TIGRFAM TIGR03673 uL14_arch: 50S ribosomal protein uL14 15 140 5.8E-61 T 31-10-2018 IPR019971 Ribosomal protein L14P, archaeal TK1980 34408d52dfd761f18d1dc3fcd4b79612 395 SUPERFAMILY SSF52518 7 253 2.36E-69 T 31-10-2018 IPR029061 Thiamin diphosphate-binding fold TK1980 34408d52dfd761f18d1dc3fcd4b79612 395 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 19 241 1.1E-77 T 31-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 TK1980 34408d52dfd761f18d1dc3fcd4b79612 395 Gene3D G3DSA:3.40.50.920 255 395 1.6E-45 T 31-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TK1980 34408d52dfd761f18d1dc3fcd4b79612 395 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 265 368 4.5E-34 T 31-10-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II TK1980 34408d52dfd761f18d1dc3fcd4b79612 395 SUPERFAMILY SSF52922 256 377 1.2E-36 T 31-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TK1980 34408d52dfd761f18d1dc3fcd4b79612 395 Gene3D G3DSA:3.40.50.970 6 254 5.5E-99 T 31-10-2018 TK0326 9d9e4b5e4299550fa42b799a4bf9c976 252 ProSitePatterns PS00211 ABC transporters family signature. 130 144 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TK0326 9d9e4b5e4299550fa42b799a4bf9c976 252 SMART SM00382 28 205 2.6E-4 T 31-10-2018 IPR003593 AAA+ ATPase domain TK0326 9d9e4b5e4299550fa42b799a4bf9c976 252 SUPERFAMILY SSF52540 2 222 2.88E-45 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK0326 9d9e4b5e4299550fa42b799a4bf9c976 252 Pfam PF00005 ABC transporter 22 157 8.3E-19 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TK0326 9d9e4b5e4299550fa42b799a4bf9c976 252 Gene3D G3DSA:3.40.50.300 1 237 7.5E-47 T 31-10-2018 TK0537 56711f1cd80b3fc4249d02fec2e65d98 216 Pfam PF00578 AhpC/TSA family 4 134 2.3E-32 T 31-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 TK0537 56711f1cd80b3fc4249d02fec2e65d98 216 SUPERFAMILY SSF52833 1 215 1.21E-63 T 31-10-2018 IPR036249 Thioredoxin-like superfamily TK0537 56711f1cd80b3fc4249d02fec2e65d98 216 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 155 195 4.6E-10 T 31-10-2018 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 TK0537 56711f1cd80b3fc4249d02fec2e65d98 216 Hamap MF_00401 Peroxiredoxin. 2 215 52.036 T 31-10-2018 IPR022915 Peroxiredoxin, TDXH subfamily GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 TK0537 56711f1cd80b3fc4249d02fec2e65d98 216 PIRSF PIRSF000239 1 215 1.8E-70 T 31-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 TK0537 56711f1cd80b3fc4249d02fec2e65d98 216 Gene3D G3DSA:3.40.30.10 1 144 5.3E-45 T 31-10-2018 TK0537 56711f1cd80b3fc4249d02fec2e65d98 216 Gene3D G3DSA:3.30.1020.10 145 216 1.0E-34 T 31-10-2018 TK2093 9af414f1d69bd3f1b15645b6888148bf 143 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 77 88 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TK2093 9af414f1d69bd3f1b15645b6888148bf 143 SUPERFAMILY SSF54862 27 112 9.21E-22 T 31-10-2018 TK2093 9af414f1d69bd3f1b15645b6888148bf 143 Pfam PF13187 4Fe-4S dicluster domain 45 91 2.7E-11 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TK2093 9af414f1d69bd3f1b15645b6888148bf 143 Gene3D G3DSA:3.30.70.3270 23 143 4.9E-22 T 31-10-2018 TK0727 37577d1222feb632a3fb6d0159d3a149 314 Gene3D G3DSA:3.40.50.300 1 225 2.0E-63 T 31-10-2018 TK0727 37577d1222feb632a3fb6d0159d3a149 314 SMART SM00382 31 208 3.5E-9 T 31-10-2018 IPR003593 AAA+ ATPase domain TK0727 37577d1222feb632a3fb6d0159d3a149 314 SUPERFAMILY SSF52540 6 219 5.75E-60 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK0727 37577d1222feb632a3fb6d0159d3a149 314 Pfam PF00005 ABC transporter 23 160 3.5E-28 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TK0844 e3a1b684b57fd8ad04ba7b4283044443 621 Gene3D G3DSA:1.10.599.10 235 598 8.7E-91 T 31-10-2018 IPR013985 Aldehyde ferredoxin oxidoreductase, domain 3 GO:0016625|GO:0051536|GO:0055114 KEGG: 00030+1.2.7.5 TK0844 e3a1b684b57fd8ad04ba7b4283044443 621 Gene3D G3DSA:3.60.9.10 1 207 1.5E-73 T 31-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily TK0844 e3a1b684b57fd8ad04ba7b4283044443 621 Gene3D G3DSA:1.10.569.10 237 428 8.7E-91 T 31-10-2018 IPR013984 Aldehyde ferredoxin oxidoreductase, domain 2 TK0844 e3a1b684b57fd8ad04ba7b4283044443 621 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 7 200 9.4E-69 T 31-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 TK0844 e3a1b684b57fd8ad04ba7b4283044443 621 SUPERFAMILY SSF48310 207 601 1.07E-104 T 31-10-2018 IPR036021 Aldehyde ferredoxin oxidoreductase-like, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 TK0844 e3a1b684b57fd8ad04ba7b4283044443 621 SMART SM00790 4 204 5.6E-115 T 31-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 TK0844 e3a1b684b57fd8ad04ba7b4283044443 621 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 218 598 3.5E-97 T 31-10-2018 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 TK0844 e3a1b684b57fd8ad04ba7b4283044443 621 SUPERFAMILY SSF56228 1 203 3.53E-67 T 31-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily TK0104 16bfc79ac8c8c018691cda78138a31f6 172 SUPERFAMILY SSF56349 20 160 1.38E-10 T 31-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 TK0104 16bfc79ac8c8c018691cda78138a31f6 172 Gene3D G3DSA:1.10.443.10 13 170 1.1E-9 T 31-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 TK0337 44aebd409ed3bd92472381dcbad8cf54 178 Gene3D G3DSA:3.40.50.1010 2 125 4.6E-42 T 31-10-2018 TK0337 44aebd409ed3bd92472381dcbad8cf54 178 SUPERFAMILY SSF88723 58 121 3.6E-6 T 31-10-2018 IPR029060 PIN-like domain superfamily TK0337 44aebd409ed3bd92472381dcbad8cf54 178 Gene3D G3DSA:2.20.28.10 126 166 6.4E-19 T 31-10-2018 TK0337 44aebd409ed3bd92472381dcbad8cf54 178 SMART SM00670 9 107 1.5E-4 T 31-10-2018 IPR002716 PIN domain TK0337 44aebd409ed3bd92472381dcbad8cf54 178 Pfam PF17146 PIN domain of ribonuclease 14 94 1.1E-18 T 31-10-2018 IPR033411 Ribonuclease, PIN domain Reactome: R-HSA-6791226 TK1290 0bc2c1b05d673ed1f323d27912712448 138 Pfam PF01850 PIN domain 3 133 6.0E-21 T 31-10-2018 IPR002716 PIN domain TK1290 0bc2c1b05d673ed1f323d27912712448 138 SMART SM00670 1 130 0.0015 T 31-10-2018 IPR002716 PIN domain TK1290 0bc2c1b05d673ed1f323d27912712448 138 SUPERFAMILY SSF88723 1 136 1.96E-22 T 31-10-2018 IPR029060 PIN-like domain superfamily TK1290 0bc2c1b05d673ed1f323d27912712448 138 Gene3D G3DSA:3.40.50.1010 2 137 5.6E-20 T 31-10-2018 TK2202 7e3333d832369d06a21e7b6a4100138a 437 Pfam PF13635 Domain of unknown function (DUF4143) 228 368 2.9E-10 T 31-10-2018 IPR025420 Domain of unknown function DUF4143 TK2202 7e3333d832369d06a21e7b6a4100138a 437 Pfam PF13173 AAA domain 49 173 1.3E-30 T 31-10-2018 TK2202 7e3333d832369d06a21e7b6a4100138a 437 SMART SM00382 47 168 0.003 T 31-10-2018 IPR003593 AAA+ ATPase domain TK2202 7e3333d832369d06a21e7b6a4100138a 437 SUPERFAMILY SSF52540 30 227 2.57E-16 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK2202 7e3333d832369d06a21e7b6a4100138a 437 Gene3D G3DSA:3.40.50.300 30 166 1.0E-5 T 31-10-2018 TK0834 096c204c17844d4bb2f137eb64fdc469 192 SUPERFAMILY SSF46785 2 59 3.22E-16 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TK0834 096c204c17844d4bb2f137eb64fdc469 192 ProSitePatterns PS00519 AsnC-type HTH domain signature. 21 47 - T 31-10-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site TK0834 096c204c17844d4bb2f137eb64fdc469 192 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 30 49 3.6E-15 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TK0834 096c204c17844d4bb2f137eb64fdc469 192 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 19 30 3.6E-15 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TK0834 096c204c17844d4bb2f137eb64fdc469 192 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 3 19 3.6E-15 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TK0834 096c204c17844d4bb2f137eb64fdc469 192 SMART SM00344 3 102 1.3E-22 T 31-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 TK0834 096c204c17844d4bb2f137eb64fdc469 192 SMART SM00746 143 179 1.8E-10 T 31-10-2018 IPR011017 TRASH domain TK0834 096c204c17844d4bb2f137eb64fdc469 192 Pfam PF08394 Archaeal TRASH domain 143 179 7.3E-21 T 31-10-2018 IPR013603 TRASH transcription regulator C-terminal, archaeal TK0834 096c204c17844d4bb2f137eb64fdc469 192 Pfam PF13412 Winged helix-turn-helix DNA-binding 4 50 1.6E-16 T 31-10-2018 TK0834 096c204c17844d4bb2f137eb64fdc469 192 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 33 49 2.8E-6 T 31-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TK0834 096c204c17844d4bb2f137eb64fdc469 192 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 19 33 2.8E-6 T 31-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TK0834 096c204c17844d4bb2f137eb64fdc469 192 Gene3D G3DSA:1.10.10.10 1 54 1.7E-21 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TK0207 2fa873c2d07dd337b69f378f5606157d 429 Gene3D G3DSA:3.30.470.20 201 429 4.0E-80 T 31-10-2018 TK0207 2fa873c2d07dd337b69f378f5606157d 429 SUPERFAMILY SSF56059 118 324 1.45E-51 T 31-10-2018 TK0207 2fa873c2d07dd337b69f378f5606157d 429 Gene3D G3DSA:3.40.50.20 1 128 3.3E-55 T 31-10-2018 TK0207 2fa873c2d07dd337b69f378f5606157d 429 Hamap MF_01643 Formate-dependent phosphoribosylglycinamide formyltransferase [purT]. 12 411 48.878 T 31-10-2018 IPR005862 Formate-dependent phosphoribosylglycinamide formyltransferase GO:0000287|GO:0004644|GO:0005524|GO:0009152|GO:0016742 TK0207 2fa873c2d07dd337b69f378f5606157d 429 TIGRFAM TIGR01142 purT: phosphoribosylglycinamide formyltransferase 2 18 410 5.2E-188 T 31-10-2018 IPR005862 Formate-dependent phosphoribosylglycinamide formyltransferase GO:0000287|GO:0004644|GO:0005524|GO:0009152|GO:0016742 TK0207 2fa873c2d07dd337b69f378f5606157d 429 SUPERFAMILY SSF52440 8 115 2.73E-33 T 31-10-2018 IPR016185 Pre-ATP-grasp domain superfamily TK0207 2fa873c2d07dd337b69f378f5606157d 429 Pfam PF02222 ATP-grasp domain 127 303 5.9E-56 T 31-10-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type TK0207 2fa873c2d07dd337b69f378f5606157d 429 SUPERFAMILY SSF51246 339 410 5.34E-18 T 31-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 TK0207 2fa873c2d07dd337b69f378f5606157d 429 Gene3D G3DSA:3.30.1490.20 129 200 1.7E-32 T 31-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 TK1688 fa2a93b1d57975e22d4d8b502d8fd560 243 Pfam PF01381 Helix-turn-helix 28 75 6.2E-9 T 31-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TK1688 fa2a93b1d57975e22d4d8b502d8fd560 243 SUPERFAMILY SSF47413 22 75 6.66E-12 T 31-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TK1688 fa2a93b1d57975e22d4d8b502d8fd560 243 Gene3D G3DSA:1.10.260.40 24 80 8.9E-11 T 31-10-2018 TK1688 fa2a93b1d57975e22d4d8b502d8fd560 243 PIRSF PIRSF037724 1 237 1.8E-104 T 31-10-2018 IPR017271 Transcription regulator HTH, MJ1545, predicted TK1688 fa2a93b1d57975e22d4d8b502d8fd560 243 SMART SM00530 26 81 3.4E-12 T 31-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TK1479 a3470fca27e4152f2dc19401e1a61f80 277 ProSitePatterns PS01232 Purine and other phosphorylases family 1 signature. 76 91 - T 31-10-2018 IPR018016 Nucleoside phosphorylase, conserved site GO:0016763 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-73614|Reactome: R-HSA-73621 TK1479 a3470fca27e4152f2dc19401e1a61f80 277 Gene3D G3DSA:3.40.50.1580 7 261 1.8E-86 T 31-10-2018 TK1479 a3470fca27e4152f2dc19401e1a61f80 277 TIGRFAM TIGR01718 Uridine-psphlse: uridine phosphorylase 18 257 1.0E-96 T 31-10-2018 IPR010058 Uridine phosphorylase GO:0004850|GO:0005737|GO:0009166 KEGG: 00240+2.4.2.3|KEGG: 00983+2.4.2.3|MetaCyc: PWY-5532 TK1479 a3470fca27e4152f2dc19401e1a61f80 277 Pfam PF01048 Phosphorylase superfamily 31 256 2.2E-45 T 31-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 TK1479 a3470fca27e4152f2dc19401e1a61f80 277 SUPERFAMILY SSF53167 17 247 1.28E-75 T 31-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 TK1461 b3915bed26e7dd6710b7e398a4da6681 967 Hamap MF_00049_A Leucine--tRNA ligase [leuS]. 6 967 18.489 T 31-10-2018 IPR020791 Leucine-tRNA ligase, archaeal GO:0000166|GO:0004823|GO:0005524|GO:0005737|GO:0006429 KEGG: 00970+6.1.1.4 TK1461 b3915bed26e7dd6710b7e398a4da6681 967 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 43 54 - T 31-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 TK1461 b3915bed26e7dd6710b7e398a4da6681 967 Gene3D G3DSA:3.40.50.620 9 688 4.4E-302 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TK1461 b3915bed26e7dd6710b7e398a4da6681 967 Gene3D G3DSA:1.10.10.720 866 917 7.1E-49 T 31-10-2018 TK1461 b3915bed26e7dd6710b7e398a4da6681 967 SUPERFAMILY SSF52374 4 694 1.71E-102 T 31-10-2018 TK1461 b3915bed26e7dd6710b7e398a4da6681 967 SUPERFAMILY SSF47323 715 903 1.87E-39 T 31-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 TK1461 b3915bed26e7dd6710b7e398a4da6681 967 Gene3D G3DSA:3.90.740.10 205 451 4.4E-302 T 31-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 TK1461 b3915bed26e7dd6710b7e398a4da6681 967 Gene3D G3DSA:1.10.730.10 690 810 1.6E-35 T 31-10-2018 TK1461 b3915bed26e7dd6710b7e398a4da6681 967 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 12 689 3.3E-67 T 31-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 TK1461 b3915bed26e7dd6710b7e398a4da6681 967 Pfam PF08264 Anticodon-binding domain of tRNA 726 859 5.3E-32 T 31-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 TK1461 b3915bed26e7dd6710b7e398a4da6681 967 SUPERFAMILY SSF50677 210 443 7.12E-34 T 31-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 TK1461 b3915bed26e7dd6710b7e398a4da6681 967 Gene3D G3DSA:3.30.2320.20 835 967 7.1E-49 T 31-10-2018 TK1461 b3915bed26e7dd6710b7e398a4da6681 967 TIGRFAM TIGR00395 leuS_arch: leucine--tRNA ligase 8 967 0.0 T 31-10-2018 IPR004493 Leucyl-tRNA synthetase, class Ia, archaeal/eukaryotic cytosolic GO:0000166|GO:0004823|GO:0005524|GO:0005737|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 TK1285 ad837ebf6cbaf97446b058c3515d0e24 151 SUPERFAMILY SSF54909 66 151 2.15E-22 T 31-10-2018 IPR011008 Dimeric alpha-beta barrel TK1285 ad837ebf6cbaf97446b058c3515d0e24 151 Pfam PF01037 Lrp/AsnC ligand binding domain 72 141 1.4E-18 T 31-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain TK1285 ad837ebf6cbaf97446b058c3515d0e24 151 Pfam PF13404 AsnC-type helix-turn-helix domain 6 47 1.2E-15 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TK1285 ad837ebf6cbaf97446b058c3515d0e24 151 SUPERFAMILY SSF46785 6 66 2.19E-17 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TK1285 ad837ebf6cbaf97446b058c3515d0e24 151 SMART SM00344 6 112 6.6E-48 T 31-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 TK1285 ad837ebf6cbaf97446b058c3515d0e24 151 Gene3D G3DSA:1.10.10.10 4 56 4.6E-23 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TK1285 ad837ebf6cbaf97446b058c3515d0e24 151 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 22 33 3.9E-17 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TK1285 ad837ebf6cbaf97446b058c3515d0e24 151 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 6 22 3.9E-17 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TK1285 ad837ebf6cbaf97446b058c3515d0e24 151 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 33 52 3.9E-17 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TK1285 ad837ebf6cbaf97446b058c3515d0e24 151 Gene3D G3DSA:3.30.70.920 58 151 1.6E-28 T 31-10-2018 TK0572 730d9b658e7d2a934de4e59d739c7ef6 353 TIGRFAM TIGR01187 potA: polyamine ABC transporter, ATP-binding protein 34 310 2.5E-107 T 31-10-2018 IPR005893 Spermidine/putrescine ABC transporter, ATP-binding subunit GO:0015417|GO:0015846|GO:0043190 TK0572 730d9b658e7d2a934de4e59d739c7ef6 353 Gene3D G3DSA:3.40.50.300 1 237 3.7E-79 T 31-10-2018 TK0572 730d9b658e7d2a934de4e59d739c7ef6 353 Pfam PF00005 ABC transporter 20 161 4.8E-35 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TK0572 730d9b658e7d2a934de4e59d739c7ef6 353 SUPERFAMILY SSF50331 237 350 4.76E-14 T 31-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal TK0572 730d9b658e7d2a934de4e59d739c7ef6 353 Gene3D G3DSA:2.40.50.100 238 346 2.5E-7 T 31-10-2018 TK0572 730d9b658e7d2a934de4e59d739c7ef6 353 Pfam PF08402 TOBE domain 275 349 3.1E-7 T 31-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 TK0572 730d9b658e7d2a934de4e59d739c7ef6 353 SUPERFAMILY SSF52540 4 244 7.72E-90 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK0572 730d9b658e7d2a934de4e59d739c7ef6 353 Gene3D G3DSA:2.40.50.140 289 340 2.5E-7 T 31-10-2018 TK0572 730d9b658e7d2a934de4e59d739c7ef6 353 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TK0572 730d9b658e7d2a934de4e59d739c7ef6 353 SMART SM00382 28 211 3.5E-16 T 31-10-2018 IPR003593 AAA+ ATPase domain TK0476 ef6f2c5f875a98a15929e1723260b091 247 SUPERFAMILY SSF55307 156 244 7.55E-12 T 31-10-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 TK0476 ef6f2c5f875a98a15929e1723260b091 247 Gene3D G3DSA:3.40.50.1440 105 245 1.7E-8 T 31-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 TK0272 f84b5188cadffa861c846cd84752f363 103 SUPERFAMILY SSF51735 1 102 1.63E-24 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily TK0272 f84b5188cadffa861c846cd84752f363 103 Gene3D G3DSA:3.40.50.720 1 103 5.0E-27 T 31-10-2018 TK0272 f84b5188cadffa861c846cd84752f363 103 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 2 90 3.0E-24 T 31-10-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal TK1236 f283ae716faec2a592bb641eacd8d440 358 SUPERFAMILY SSF46785 286 355 1.95E-20 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TK1236 f283ae716faec2a592bb641eacd8d440 358 Pfam PF01637 ATPase domain predominantly from Archaea 15 251 7.4E-23 T 31-10-2018 IPR011579 ATPase domain GO:0005524 TK1236 f283ae716faec2a592bb641eacd8d440 358 Gene3D G3DSA:1.10.10.10 288 357 4.7E-29 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TK1236 f283ae716faec2a592bb641eacd8d440 358 Gene3D G3DSA:1.10.8.60 210 287 1.4E-27 T 31-10-2018 TK1236 f283ae716faec2a592bb641eacd8d440 358 Gene3D G3DSA:3.40.50.300 1 209 1.7E-44 T 31-10-2018 TK1236 f283ae716faec2a592bb641eacd8d440 358 SUPERFAMILY SSF52540 1 283 1.96E-44 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK0733 333ec4f792ff61159428cb50fb7e239f 66 Pfam PF01954 Protein of unknown function DUF104 1 60 1.9E-15 T 31-10-2018 IPR008203 Uncharacterised protein family UPF0165 TK0733 333ec4f792ff61159428cb50fb7e239f 66 SUPERFAMILY SSF141694 1 61 3.14E-15 T 31-10-2018 TK0733 333ec4f792ff61159428cb50fb7e239f 66 Gene3D G3DSA:4.10.1150.10 1 65 1.2E-12 T 31-10-2018 IPR024069 AF2212-like domain superfamily TK0378 da66e47df6f9ff9b064b8352357114a6 242 SMART SM00470 19 114 8.1E-11 T 31-10-2018 IPR003115 ParB/Sulfiredoxin TK0378 da66e47df6f9ff9b064b8352357114a6 242 Gene3D G3DSA:3.30.1760.10 98 227 5.4E-84 T 31-10-2018 IPR023098 ParB-like nuclease, C-terminal TK0378 da66e47df6f9ff9b064b8352357114a6 242 SUPERFAMILY SSF110849 12 241 5.1E-61 T 31-10-2018 IPR036086 ParB/Sulfiredoxin superfamily TK0378 da66e47df6f9ff9b064b8352357114a6 242 Gene3D G3DSA:3.90.1530.10 17 238 5.4E-84 T 31-10-2018 TK0378 da66e47df6f9ff9b064b8352357114a6 242 Pfam PF02195 ParB-like nuclease domain 22 92 2.0E-9 T 31-10-2018 IPR003115 ParB/Sulfiredoxin TK0340 eeb25924670f0d1772e7d0be1fb3ecb3 122 Pfam PF05168 HEPN domain 3 116 2.0E-24 T 31-10-2018 IPR007842 HEPN domain TK0340 eeb25924670f0d1772e7d0be1fb3ecb3 122 Gene3D G3DSA:1.20.120.330 2 120 1.4E-30 T 31-10-2018 TK0340 eeb25924670f0d1772e7d0be1fb3ecb3 122 SUPERFAMILY SSF81593 4 118 1.96E-7 T 31-10-2018 TK0533 c90e00ec06b1b5a179a0a92590eb94db 110 SMART SM00661 2 56 9.8E-15 T 31-10-2018 IPR001529 DNA-directed RNA polymerase, M/15kDa subunit GO:0006351 TK0533 c90e00ec06b1b5a179a0a92590eb94db 110 Gene3D G3DSA:2.20.25.10 55 110 1.5E-28 T 31-10-2018 TK0533 c90e00ec06b1b5a179a0a92590eb94db 110 SUPERFAMILY SSF57783 1 34 2.98E-6 T 31-10-2018 TK0533 c90e00ec06b1b5a179a0a92590eb94db 110 Pfam PF02150 RNA polymerases M/15 Kd subunit 1 34 2.2E-16 T 31-10-2018 IPR001529 DNA-directed RNA polymerase, M/15kDa subunit GO:0006351 TK0533 c90e00ec06b1b5a179a0a92590eb94db 110 SMART SM00440 69 108 1.9E-23 T 31-10-2018 IPR001222 Zinc finger, TFIIS-type GO:0003676|GO:0006351|GO:0008270 TK0533 c90e00ec06b1b5a179a0a92590eb94db 110 SUPERFAMILY SSF57783 48 109 5.21E-23 T 31-10-2018 TK0533 c90e00ec06b1b5a179a0a92590eb94db 110 Pfam PF01096 Transcription factor S-II (TFIIS) 70 107 6.4E-21 T 31-10-2018 IPR001222 Zinc finger, TFIIS-type GO:0003676|GO:0006351|GO:0008270 TK0533 c90e00ec06b1b5a179a0a92590eb94db 110 ProSitePatterns PS00466 Zinc finger TFIIS-type signature. 71 106 - T 31-10-2018 IPR001222 Zinc finger, TFIIS-type GO:0003676|GO:0006351|GO:0008270 TK0533 c90e00ec06b1b5a179a0a92590eb94db 110 ProSitePatterns PS01030 RNA polymerases M / 15 Kd subunits signature. 3 25 - T 31-10-2018 IPR019761 DNA-directed RNA polymerase M, 15kDa subunit, conserved site TK0533 c90e00ec06b1b5a179a0a92590eb94db 110 TIGRFAM TIGR01384 TFS_arch: transcription factor S 2 110 1.6E-38 T 31-10-2018 IPR006288 Transcription factor S GO:0006355 TK0533 c90e00ec06b1b5a179a0a92590eb94db 110 PIRSF PIRSF005586 1 110 6.1E-38 T 31-10-2018 IPR012164 DNA-directed RNA polymerase subunit/transcription factor S GO:0006351 TK2206 a24f250d2d8f5bc29572f064424a8b3e 367 Pfam PF13699 Domain of unknown function (DUF4157) 105 149 9.4E-5 T 31-10-2018 IPR025295 Domain of unknown function DUF4157 TK0179 305a69d2665882b6e9616aef2415362d 134 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 17 47 2.6E-9 T 31-10-2018 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal TK0179 305a69d2665882b6e9616aef2415362d 134 SUPERFAMILY SSF50249 8 116 6.51E-32 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold TK0179 305a69d2665882b6e9616aef2415362d 134 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 50 112 2.7E-21 T 31-10-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal TK1312 05a6a1972b27ae3a047b168c2047a4c7 394 Gene3D G3DSA:3.30.1380.20 251 394 2.0E-12 T 31-10-2018 TK1312 05a6a1972b27ae3a047b168c2047a4c7 394 SUPERFAMILY SSF52540 2 201 9.51E-16 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK1312 05a6a1972b27ae3a047b168c2047a4c7 394 SMART SM00989 330 392 1.2E-13 T 31-10-2018 IPR004096 4-vinyl reductase, 4VR TK1312 05a6a1972b27ae3a047b168c2047a4c7 394 SUPERFAMILY SSF111126 253 389 1.57E-19 T 31-10-2018 IPR024096 NO signalling/Golgi transport ligand-binding domain superfamily TK1312 05a6a1972b27ae3a047b168c2047a4c7 394 Pfam PF06745 KaiC 3 166 8.4E-14 T 31-10-2018 IPR014774 KaiC-like domain TK1312 05a6a1972b27ae3a047b168c2047a4c7 394 Pfam PF02830 V4R domain 346 390 3.5E-13 T 31-10-2018 IPR004096 4-vinyl reductase, 4VR TK1312 05a6a1972b27ae3a047b168c2047a4c7 394 Gene3D G3DSA:3.40.50.300 1 228 1.3E-20 T 31-10-2018 TK0957 e4aad41f63907f22c2a141fff80c7ce6 660 SUPERFAMILY SSF52540 6 174 3.9E-43 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK0957 e4aad41f63907f22c2a141fff80c7ce6 660 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 27 45 6.3E-6 T 31-10-2018 IPR006073 GTP binding domain GO:0005525 TK0957 e4aad41f63907f22c2a141fff80c7ce6 660 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 6 26 6.3E-6 T 31-10-2018 IPR006073 GTP binding domain GO:0005525 TK0957 e4aad41f63907f22c2a141fff80c7ce6 660 Pfam PF07670 Nucleoside recognition 354 448 6.1E-14 T 31-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 TK0957 e4aad41f63907f22c2a141fff80c7ce6 660 Pfam PF07670 Nucleoside recognition 515 629 1.1E-28 T 31-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 TK0957 e4aad41f63907f22c2a141fff80c7ce6 660 Pfam PF02421 Ferrous iron transport protein B 5 160 1.7E-65 T 31-10-2018 IPR030389 FeoB-type guanine nucleotide-binding (G) domain GO:0005525 TK0957 e4aad41f63907f22c2a141fff80c7ce6 660 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 3 158 3.3E-12 T 31-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 TK0957 e4aad41f63907f22c2a141fff80c7ce6 660 Pfam PF07664 Ferrous iron transport protein B C terminus 458 510 8.1E-19 T 31-10-2018 IPR011640 Ferrous iron transport protein B, C-terminal GO:0015093|GO:0015684|GO:0016021 TK0957 e4aad41f63907f22c2a141fff80c7ce6 660 TIGRFAM TIGR00437 feoB: ferrous iron transport protein B 10 626 4.1E-187 T 31-10-2018 IPR003373 Ferrous iron transport protein B GO:0005525|GO:0015093|GO:0015684|GO:0016021 TK0957 e4aad41f63907f22c2a141fff80c7ce6 660 Gene3D G3DSA:3.40.50.300 1 170 8.9E-48 T 31-10-2018 TK0610 cac29d167509d88bd773d79d3bb6d994 628 Gene3D G3DSA:2.60.40.1120 222 289 2.8E-5 T 31-10-2018 TK0610 cac29d167509d88bd773d79d3bb6d994 628 SUPERFAMILY SSF49464 222 293 5.89E-5 T 31-10-2018 IPR008969 Carboxypeptidase-like, regulatory domain superfamily TK1519 b187ff583eefa5af71c95c9f41ecb985 148 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 1 148 14.983 T 31-10-2018 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 TK1519 b187ff583eefa5af71c95c9f41ecb985 148 Gene3D G3DSA:3.100.10.10 63 148 3.0E-20 T 31-10-2018 TK1519 b187ff583eefa5af71c95c9f41ecb985 148 ProSitePatterns PS00475 Ribosomal protein L15 signature. 112 142 - T 31-10-2018 IPR001196 Ribosomal protein L15, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1519 b187ff583eefa5af71c95c9f41ecb985 148 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 29 146 1.8E-19 T 31-10-2018 IPR021131 Ribosomal protein L18e/L15P TK1519 b187ff583eefa5af71c95c9f41ecb985 148 SUPERFAMILY SSF52080 5 147 2.88E-33 T 31-10-2018 IPR036227 Ribosomal L18e/L15P superfamily TK1519 b187ff583eefa5af71c95c9f41ecb985 148 Gene3D G3DSA:4.10.990.10 4 53 3.5E-10 T 31-10-2018 IPR027386 50S ribosomal protein L15, N-terminal TK0135 25dabf1a2c23c8db77faabdcdd959d36 202 SUPERFAMILY SSF53323 4 199 4.05E-44 T 31-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 TK0135 25dabf1a2c23c8db77faabdcdd959d36 202 Gene3D G3DSA:3.40.920.10 1 201 1.1E-49 T 31-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 TK0135 25dabf1a2c23c8db77faabdcdd959d36 202 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 12 193 5.9E-39 T 31-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 TK0135 25dabf1a2c23c8db77faabdcdd959d36 202 TIGRFAM TIGR03334 IOR_beta: indolepyruvate ferredoxin oxidoreductase, beta subunit 4 194 1.2E-97 T 31-10-2018 IPR017719 Indolepyruvate ferredoxin oxidoreductase, beta subunit GO:0043805|GO:0055114 TK0809 723498db97b3c784f0881e4cefb7a206 602 Gene3D G3DSA:3.60.20.10 2 240 5.4E-79 T 31-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TK0809 723498db97b3c784f0881e4cefb7a206 602 SUPERFAMILY SSF56235 2 229 1.72E-74 T 31-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TK0809 723498db97b3c784f0881e4cefb7a206 602 Pfam PF01380 SIS domain 457 584 1.4E-24 T 31-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 TK0809 723498db97b3c784f0881e4cefb7a206 602 Pfam PF01380 SIS domain 284 412 6.8E-32 T 31-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 TK0809 723498db97b3c784f0881e4cefb7a206 602 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 602 41.031 T 31-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 TK0809 723498db97b3c784f0881e4cefb7a206 602 Gene3D G3DSA:3.40.50.10490 442 587 8.5E-138 T 31-10-2018 TK0809 723498db97b3c784f0881e4cefb7a206 602 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 602 1.2E-248 T 31-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 TK0809 723498db97b3c784f0881e4cefb7a206 602 SUPERFAMILY SSF53697 247 602 4.92E-110 T 31-10-2018 TK0809 723498db97b3c784f0881e4cefb7a206 602 Gene3D G3DSA:3.40.50.10490 251 601 8.5E-138 T 31-10-2018 TK0809 723498db97b3c784f0881e4cefb7a206 602 Pfam PF13522 Glutamine amidotransferase domain 65 193 7.9E-24 T 31-10-2018 TK1738 30b6bb4e32497a8515b15b1e0eaba47d 184 Hamap MF_01940 RNA 2',3'-cyclic phosphodiesterase [thpR]. 1 182 27.551 T 31-10-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 TK1738 30b6bb4e32497a8515b15b1e0eaba47d 184 SUPERFAMILY SSF55144 1 182 1.26E-47 T 31-10-2018 IPR009097 Cyclic phosphodiesterase TK1738 30b6bb4e32497a8515b15b1e0eaba47d 184 TIGRFAM TIGR02258 2_5_ligase: 2'-5' RNA ligase 1 182 2.5E-56 T 31-10-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 TK1738 30b6bb4e32497a8515b15b1e0eaba47d 184 Pfam PF02834 LigT like Phosphoesterase 7 91 8.0E-22 T 31-10-2018 IPR014051 Phosphoesterase, HXTX TK1738 30b6bb4e32497a8515b15b1e0eaba47d 184 Pfam PF02834 LigT like Phosphoesterase 98 174 1.7E-13 T 31-10-2018 IPR014051 Phosphoesterase, HXTX TK1738 30b6bb4e32497a8515b15b1e0eaba47d 184 Gene3D G3DSA:3.90.1140.10 1 184 3.3E-68 T 31-10-2018 TK0223 c9f780fec695eb3ef777d906de65e145 389 SUPERFAMILY SSF103473 24 387 8.63E-30 T 31-10-2018 IPR036259 MFS transporter superfamily TK0223 c9f780fec695eb3ef777d906de65e145 389 Gene3D G3DSA:1.20.1250.20 18 385 8.3E-27 T 31-10-2018 TK0223 c9f780fec695eb3ef777d906de65e145 389 Pfam PF07690 Major Facilitator Superfamily 25 350 1.6E-10 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TK1703 7a5780cabfb8fb38be792cc3d59f9ab6 355 PRINTS PR00728 Eukaryotic signal peptidase (S26B) family signature 86 97 3.1E-6 T 31-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 TK1703 7a5780cabfb8fb38be792cc3d59f9ab6 355 PRINTS PR00728 Eukaryotic signal peptidase (S26B) family signature 35 50 3.1E-6 T 31-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 TK1703 7a5780cabfb8fb38be792cc3d59f9ab6 355 Pfam PF00717 Peptidase S24-like 36 91 5.8E-10 T 31-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C TK1703 7a5780cabfb8fb38be792cc3d59f9ab6 355 Gene3D G3DSA:2.10.109.10 36 134 2.0E-6 T 31-10-2018 TK1703 7a5780cabfb8fb38be792cc3d59f9ab6 355 TIGRFAM TIGR02228 sigpep_I_arch: signal peptidase I 9 117 1.1E-17 T 31-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 TK1703 7a5780cabfb8fb38be792cc3d59f9ab6 355 SUPERFAMILY SSF51306 36 99 3.66E-9 T 31-10-2018 IPR036286 LexA/Signal peptidase-like superfamily TK0183 0cce441aea589bbe0f2678abc765d8b1 226 Gene3D G3DSA:3.30.200.20 1 50 1.8E-25 T 31-10-2018 TK0183 0cce441aea589bbe0f2678abc765d8b1 226 Gene3D G3DSA:3.40.50.150 51 226 1.4E-74 T 31-10-2018 TK0183 0cce441aea589bbe0f2678abc765d8b1 226 PRINTS PR00052 Fibrillarin signature 153 182 4.5E-78 T 31-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 TK0183 0cce441aea589bbe0f2678abc765d8b1 226 PRINTS PR00052 Fibrillarin signature 204 225 4.5E-78 T 31-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 TK0183 0cce441aea589bbe0f2678abc765d8b1 226 PRINTS PR00052 Fibrillarin signature 73 94 4.5E-78 T 31-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 TK0183 0cce441aea589bbe0f2678abc765d8b1 226 PRINTS PR00052 Fibrillarin signature 23 42 4.5E-78 T 31-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 TK0183 0cce441aea589bbe0f2678abc765d8b1 226 PRINTS PR00052 Fibrillarin signature 123 152 4.5E-78 T 31-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 TK0183 0cce441aea589bbe0f2678abc765d8b1 226 PRINTS PR00052 Fibrillarin signature 46 65 4.5E-78 T 31-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 TK0183 0cce441aea589bbe0f2678abc765d8b1 226 PRINTS PR00052 Fibrillarin signature 98 115 4.5E-78 T 31-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 TK0183 0cce441aea589bbe0f2678abc765d8b1 226 Pfam PF01269 Fibrillarin 4 224 2.0E-100 T 31-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 TK0183 0cce441aea589bbe0f2678abc765d8b1 226 SUPERFAMILY SSF53335 3 225 1.25E-60 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TK0183 0cce441aea589bbe0f2678abc765d8b1 226 SMART SM01206 3 226 2.0E-145 T 31-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 TK0183 0cce441aea589bbe0f2678abc765d8b1 226 ProSitePatterns PS00566 Fibrillarin signature. 98 112 - T 31-10-2018 IPR020813 Fibrillarin, conserved site GO:0003723|GO:0006364|GO:0008168 TK0183 0cce441aea589bbe0f2678abc765d8b1 226 Hamap MF_00351 Fibrillarin-like rRNA/tRNA 2'-O-methyltransferase [flpA]. 16 226 43.848 T 31-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 TK0183 0cce441aea589bbe0f2678abc765d8b1 226 PIRSF PIRSF006540 1 226 3.6E-100 T 31-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 TK0352 807b4de841361edec254ace83194ca6a 503 Gene3D G3DSA:2.40.40.20 1 83 1.2E-42 T 31-10-2018 TK0352 807b4de841361edec254ace83194ca6a 503 Gene3D G3DSA:1.20.970.10 84 151 4.1E-24 T 31-10-2018 TK0352 807b4de841361edec254ace83194ca6a 503 Gene3D G3DSA:3.40.1030.10 152 412 2.1E-103 T 31-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 TK0352 807b4de841361edec254ace83194ca6a 503 TIGRFAM TIGR03327 AMP_phos: AMP phosphorylase 3 500 2.7E-249 T 31-10-2018 IPR017713 AMP phosphorylase GO:0009032|GO:0046125 MetaCyc: PWY-5532 TK0352 807b4de841361edec254ace83194ca6a 503 Hamap MF_02132 AMP phosphorylase. 1 503 47.163 T 31-10-2018 IPR017713 AMP phosphorylase GO:0009032|GO:0046125 MetaCyc: PWY-5532 TK0352 807b4de841361edec254ace83194ca6a 503 SMART SM00941 424 491 8.8E-25 T 31-10-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 TK0352 807b4de841361edec254ace83194ca6a 503 Gene3D G3DSA:3.90.1170.30 413 493 8.1E-30 T 31-10-2018 IPR036566 Pyrimidine nucleoside phosphorylase-like, C-terminal domain superfamily GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 TK0352 807b4de841361edec254ace83194ca6a 503 SUPERFAMILY SSF47648 86 153 1.44E-16 T 31-10-2018 IPR036320 Glycosyl transferase family 3, N-terminal domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 TK0352 807b4de841361edec254ace83194ca6a 503 Pfam PF07831 Pyrimidine nucleoside phosphorylase C-terminal domain 424 487 4.2E-16 T 31-10-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 TK0352 807b4de841361edec254ace83194ca6a 503 Pfam PF02885 Glycosyl transferase family, helical bundle domain 89 150 9.0E-15 T 31-10-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 TK0352 807b4de841361edec254ace83194ca6a 503 PIRSF PIRSF000478 84 502 3.2E-126 T 31-10-2018 IPR000053 Thymidine/pyrimidine-nucleoside phosphorylase GO:0004645|GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 TK0352 807b4de841361edec254ace83194ca6a 503 ProSitePatterns PS00647 Thymidine and pyrimidine-nucleoside phosphorylases signature. 193 208 - T 31-10-2018 IPR017872 Pyrimidine-nucleoside phosphorylase, conserved site GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 TK0352 807b4de841361edec254ace83194ca6a 503 TIGRFAM TIGR02645 ARCH_P_rylase: putative thymidine phosphorylase 4 494 3.1E-230 T 31-10-2018 IPR013466 Thymidine phosphorylase/AMP phosphorylase GO:0016763 TK0352 807b4de841361edec254ace83194ca6a 503 SUPERFAMILY SSF54680 412 495 1.83E-19 T 31-10-2018 IPR036566 Pyrimidine nucleoside phosphorylase-like, C-terminal domain superfamily GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 TK0352 807b4de841361edec254ace83194ca6a 503 Pfam PF00591 Glycosyl transferase family, a/b domain 158 386 1.9E-14 T 31-10-2018 IPR000312 Glycosyl transferase, family 3 GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 TK0352 807b4de841361edec254ace83194ca6a 503 SUPERFAMILY SSF52418 155 404 6.02E-70 T 31-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 TK0986 09108fcb310dc8d858e772d023bcea68 430 Pfam PF00375 Sodium:dicarboxylate symporter family 15 418 4.4E-126 T 31-10-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 TK0986 09108fcb310dc8d858e772d023bcea68 430 PRINTS PR00173 Glutamate-aspartate symporter signature 304 330 3.2E-48 T 31-10-2018 TK0986 09108fcb310dc8d858e772d023bcea68 430 PRINTS PR00173 Glutamate-aspartate symporter signature 339 358 3.2E-48 T 31-10-2018 TK0986 09108fcb310dc8d858e772d023bcea68 430 PRINTS PR00173 Glutamate-aspartate symporter signature 366 386 3.2E-48 T 31-10-2018 TK0986 09108fcb310dc8d858e772d023bcea68 430 PRINTS PR00173 Glutamate-aspartate symporter signature 84 109 3.2E-48 T 31-10-2018 TK0986 09108fcb310dc8d858e772d023bcea68 430 PRINTS PR00173 Glutamate-aspartate symporter signature 12 32 3.2E-48 T 31-10-2018 TK0986 09108fcb310dc8d858e772d023bcea68 430 PRINTS PR00173 Glutamate-aspartate symporter signature 55 75 3.2E-48 T 31-10-2018 TK0986 09108fcb310dc8d858e772d023bcea68 430 PRINTS PR00173 Glutamate-aspartate symporter signature 203 222 3.2E-48 T 31-10-2018 TK0986 09108fcb310dc8d858e772d023bcea68 430 ProSitePatterns PS00713 Sodium:dicarboxylate symporter family signature 1. 47 62 - T 31-10-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site TK0986 09108fcb310dc8d858e772d023bcea68 430 Gene3D G3DSA:1.10.3860.10 1 430 9.4E-182 T 31-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 TK0986 09108fcb310dc8d858e772d023bcea68 430 SUPERFAMILY SSF118215 15 420 1.7E-121 T 31-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 TK0826 c6fc6ec4d7e3ad47f1ee07a39c353eaa 174 Pfam PF02915 Rubrerythrin 7 147 1.5E-13 T 31-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 TK0826 c6fc6ec4d7e3ad47f1ee07a39c353eaa 174 SUPERFAMILY SSF47240 4 154 1.53E-21 T 31-10-2018 IPR009078 Ferritin-like superfamily TK0826 c6fc6ec4d7e3ad47f1ee07a39c353eaa 174 Gene3D G3DSA:1.20.1260.10 1 152 7.5E-32 T 31-10-2018 IPR012347 Ferritin-like TK0444 36201f4acc07594438afc2d105b784df 476 SUPERFAMILY SSF47323 316 473 2.42E-34 T 31-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 TK0444 36201f4acc07594438afc2d105b784df 476 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 3 473 1.7E-182 T 31-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 TK0444 36201f4acc07594438afc2d105b784df 476 Gene3D G3DSA:3.40.50.620 1 305 5.1E-151 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TK0444 36201f4acc07594438afc2d105b784df 476 SUPERFAMILY SSF52374 4 314 1.05E-112 T 31-10-2018 TK0444 36201f4acc07594438afc2d105b784df 476 Gene3D G3DSA:1.20.120.640 306 473 8.6E-38 T 31-10-2018 TK0444 36201f4acc07594438afc2d105b784df 476 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 16 314 2.2E-138 T 31-10-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 TK0444 36201f4acc07594438afc2d105b784df 476 Pfam PF09190 DALR domain 356 415 9.2E-17 T 31-10-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 TK0444 36201f4acc07594438afc2d105b784df 476 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 222 243 2.9E-30 T 31-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 TK0444 36201f4acc07594438afc2d105b784df 476 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 191 209 2.9E-30 T 31-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 TK0444 36201f4acc07594438afc2d105b784df 476 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 26 37 2.9E-30 T 31-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 TK0444 36201f4acc07594438afc2d105b784df 476 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 62 71 2.9E-30 T 31-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 TK0444 36201f4acc07594438afc2d105b784df 476 SMART SM00840 356 417 1.1E-15 T 31-10-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 TK0444 36201f4acc07594438afc2d105b784df 476 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 3 474 39.949 T 31-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 TK2208 86c7030c9a7e7900a6ce706e06460236 242 ProSitePatterns PS00211 ABC transporters family signature. 126 140 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TK2208 86c7030c9a7e7900a6ce706e06460236 242 SMART SM00382 26 201 1.3E-16 T 31-10-2018 IPR003593 AAA+ ATPase domain TK2208 86c7030c9a7e7900a6ce706e06460236 242 Pfam PF00005 ABC transporter 17 154 1.8E-26 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TK2208 86c7030c9a7e7900a6ce706e06460236 242 Gene3D G3DSA:3.40.50.300 4 236 2.2E-60 T 31-10-2018 TK2208 86c7030c9a7e7900a6ce706e06460236 242 SUPERFAMILY SSF52540 6 213 1.74E-55 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK0981 b8cfbd687707d334fee4fd986f6854c7 331 SMART SM00981 56 141 2.6E-5 T 31-10-2018 IPR004114 THUMP domain GO:0003723 TK0981 b8cfbd687707d334fee4fd986f6854c7 331 Gene3D G3DSA:3.40.50.150 153 331 6.1E-33 T 31-10-2018 TK0981 b8cfbd687707d334fee4fd986f6854c7 331 Pfam PF01170 Putative RNA methylase family UPF0020 156 298 1.2E-25 T 31-10-2018 IPR000241 Putative RNA methylase domain TK0981 b8cfbd687707d334fee4fd986f6854c7 331 SUPERFAMILY SSF143437 40 132 4.19E-7 T 31-10-2018 TK0981 b8cfbd687707d334fee4fd986f6854c7 331 Pfam PF02926 THUMP domain 17 133 2.3E-9 T 31-10-2018 IPR004114 THUMP domain GO:0003723 TK0981 b8cfbd687707d334fee4fd986f6854c7 331 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 251 257 - T 31-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 TK0981 b8cfbd687707d334fee4fd986f6854c7 331 SUPERFAMILY SSF53335 138 294 1.41E-29 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TK0981 b8cfbd687707d334fee4fd986f6854c7 331 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 183 197 3.2E-7 T 31-10-2018 TK0981 b8cfbd687707d334fee4fd986f6854c7 331 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 270 294 3.2E-7 T 31-10-2018 TK0981 b8cfbd687707d334fee4fd986f6854c7 331 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 248 260 3.2E-7 T 31-10-2018 TK0981 b8cfbd687707d334fee4fd986f6854c7 331 TIGRFAM TIGR01177 TIGR01177: putative methyltransferase, TIGR01177 family 3 328 2.4E-99 T 31-10-2018 IPR005885 tRNA guanine(10)-N2-dimethyltransferase GO:0004809|GO:0030488 TK1416 a25d772866c5eb65d985ae7ebb9f2c15 340 Gene3D G3DSA:3.90.105.20 107 186 1.2E-74 T 31-10-2018 TK1416 a25d772866c5eb65d985ae7ebb9f2c15 340 SUPERFAMILY SSF160369 5 141 1.02E-25 T 31-10-2018 TK1416 a25d772866c5eb65d985ae7ebb9f2c15 340 Pfam PF00428 60s Acidic ribosomal protein 232 339 5.6E-7 T 31-10-2018 TK1416 a25d772866c5eb65d985ae7ebb9f2c15 340 Hamap MF_00280 50S ribosomal protein L10 [rpl10]. 1 283 36.174 T 31-10-2018 IPR022909 50S ribosomal protein L10, archaea TK1416 a25d772866c5eb65d985ae7ebb9f2c15 340 Gene3D G3DSA:3.30.70.1730 15 210 1.2E-74 T 31-10-2018 TK1416 a25d772866c5eb65d985ae7ebb9f2c15 340 Pfam PF00466 Ribosomal protein L10 5 105 1.2E-21 T 31-10-2018 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 TK0716 ab2bbc128b5fc072e7f6515d81efcba4 76 SUPERFAMILY SSF50037 10 76 3.89E-19 T 31-10-2018 IPR008988 Transcriptional repressor, C-terminal TK0716 ab2bbc128b5fc072e7f6515d81efcba4 76 Gene3D G3DSA:2.30.30.90 10 76 4.9E-24 T 31-10-2018 IPR038157 Ferrous iron transporter, core domain TK0716 ab2bbc128b5fc072e7f6515d81efcba4 76 SMART SM00899 7 76 4.0E-22 T 31-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 TK0716 ab2bbc128b5fc072e7f6515d81efcba4 76 Pfam PF04023 FeoA domain 7 76 2.3E-19 T 31-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 TK0633 b1bc6efc7b6bf239ce7f5fc763d83542 355 SUPERFAMILY SSF52738 163 348 5.36E-68 T 31-10-2018 IPR035909 Methylesterase CheB, C-terminal TK0633 b1bc6efc7b6bf239ce7f5fc763d83542 355 Pfam PF01339 CheB methylesterase 167 346 5.2E-63 T 31-10-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 TK0633 b1bc6efc7b6bf239ce7f5fc763d83542 355 Gene3D G3DSA:3.40.50.180 161 349 5.7E-74 T 31-10-2018 IPR035909 Methylesterase CheB, C-terminal TK0633 b1bc6efc7b6bf239ce7f5fc763d83542 355 PIRSF PIRSF000876 4 354 8.9E-143 T 31-10-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 TK0633 b1bc6efc7b6bf239ce7f5fc763d83542 355 SUPERFAMILY SSF52172 5 128 1.85E-32 T 31-10-2018 IPR011006 CheY-like superfamily TK0633 b1bc6efc7b6bf239ce7f5fc763d83542 355 Pfam PF00072 Response regulator receiver domain 9 113 5.3E-26 T 31-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TK0633 b1bc6efc7b6bf239ce7f5fc763d83542 355 Gene3D G3DSA:3.40.50.2300 4 144 3.0E-38 T 31-10-2018 TK0633 b1bc6efc7b6bf239ce7f5fc763d83542 355 Hamap MF_00099 Chemotaxis response regulator protein-glutamate methylesterase [cheB]. 7 351 41.57 T 31-10-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 TK0633 b1bc6efc7b6bf239ce7f5fc763d83542 355 SMART SM00448 7 126 8.0E-30 T 31-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TK1789 1b52eb73044602fb0accf7e62d8a89c5 249 SUPERFAMILY SSF52540 7 244 4.47E-46 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK1789 1b52eb73044602fb0accf7e62d8a89c5 249 Pfam PF06745 KaiC 10 246 5.2E-77 T 31-10-2018 IPR014774 KaiC-like domain TK1789 1b52eb73044602fb0accf7e62d8a89c5 249 Gene3D G3DSA:3.40.50.300 4 249 4.8E-72 T 31-10-2018 TK2001 8026ec3e6e9629add4a4975e87015460 75 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 38 54 2.7E-15 T 31-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC TK2001 8026ec3e6e9629add4a4975e87015460 75 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 2 9 2.7E-15 T 31-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC TK2001 8026ec3e6e9629add4a4975e87015460 75 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 17 33 2.7E-15 T 31-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC TK2001 8026ec3e6e9629add4a4975e87015460 75 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 56 68 2.7E-15 T 31-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC TK2001 8026ec3e6e9629add4a4975e87015460 75 Pfam PF01455 HupF/HypC family 1 65 1.9E-29 T 31-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC TK2001 8026ec3e6e9629add4a4975e87015460 75 ProSitePatterns PS01097 Hydrogenases expression/synthesis hupF/hypC family signature. 1 9 - T 31-10-2018 IPR019812 Hydrogenase assembly chaperone, conserved site TK2001 8026ec3e6e9629add4a4975e87015460 75 SUPERFAMILY SSF159127 1 74 9.68E-28 T 31-10-2018 IPR037254 HupF/HypC superfamily TK2001 8026ec3e6e9629add4a4975e87015460 75 TIGRFAM TIGR00074 hypC_hupF: hydrogenase assembly chaperone HypC/HupF 1 73 8.4E-29 T 31-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC TK2001 8026ec3e6e9629add4a4975e87015460 75 Gene3D G3DSA:2.40.50.970 1 75 1.3E-35 T 31-10-2018 IPR037254 HupF/HypC superfamily TK0132 c750cdeeb3cec8fc151d39bd0091c2e1 190 Hamap MF_00408 TATA-box-binding protein [tbp]. 5 184 37.587 T 31-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 TK0132 c750cdeeb3cec8fc151d39bd0091c2e1 190 ProSitePatterns PS00351 Transcription factor TFIID repeat signature. 129 178 - T 31-10-2018 IPR030491 TATA-box binding protein, conserved site TK0132 c750cdeeb3cec8fc151d39bd0091c2e1 190 Gene3D G3DSA:3.30.310.10 98 182 5.9E-35 T 31-10-2018 IPR012295 TBP domain superfamily TK0132 c750cdeeb3cec8fc151d39bd0091c2e1 190 Gene3D G3DSA:3.30.310.10 16 97 1.2E-31 T 31-10-2018 IPR012295 TBP domain superfamily TK0132 c750cdeeb3cec8fc151d39bd0091c2e1 190 Pfam PF00352 Transcription factor TFIID (or TATA-binding protein, TBP) 9 89 1.5E-26 T 31-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 TK0132 c750cdeeb3cec8fc151d39bd0091c2e1 190 Pfam PF00352 Transcription factor TFIID (or TATA-binding protein, TBP) 100 181 2.6E-28 T 31-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 TK0132 c750cdeeb3cec8fc151d39bd0091c2e1 190 PRINTS PR00686 Transcription initiation factor TFIID signature 125 140 3.9E-42 T 31-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 TK0132 c750cdeeb3cec8fc151d39bd0091c2e1 190 PRINTS PR00686 Transcription initiation factor TFIID signature 35 54 3.9E-42 T 31-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 TK0132 c750cdeeb3cec8fc151d39bd0091c2e1 190 PRINTS PR00686 Transcription initiation factor TFIID signature 102 118 3.9E-42 T 31-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 TK0132 c750cdeeb3cec8fc151d39bd0091c2e1 190 PRINTS PR00686 Transcription initiation factor TFIID signature 144 160 3.9E-42 T 31-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 TK0132 c750cdeeb3cec8fc151d39bd0091c2e1 190 PRINTS PR00686 Transcription initiation factor TFIID signature 11 26 3.9E-42 T 31-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 TK0132 c750cdeeb3cec8fc151d39bd0091c2e1 190 PRINTS PR00686 Transcription initiation factor TFIID signature 54 72 3.9E-42 T 31-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 TK0132 c750cdeeb3cec8fc151d39bd0091c2e1 190 SUPERFAMILY SSF55945 5 95 5.5E-29 T 31-10-2018 TK0132 c750cdeeb3cec8fc151d39bd0091c2e1 190 SUPERFAMILY SSF55945 95 182 1.88E-30 T 31-10-2018 TK1174 ec85fd052a58d6b4f02d5c71d0cc3943 173 SUPERFAMILY SSF51161 2 169 3.19E-50 T 31-10-2018 IPR011004 Trimeric LpxA-like superfamily TK1174 ec85fd052a58d6b4f02d5c71d0cc3943 173 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 89 121 5.8E-7 T 31-10-2018 IPR001451 Hexapeptide repeat TK1174 ec85fd052a58d6b4f02d5c71d0cc3943 173 Gene3D G3DSA:2.160.10.10 1 172 1.4E-63 T 31-10-2018 TK0200 3eb2c1105160ff865c01ece414d846e9 498 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 48 189 1.3E-23 T 31-10-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 TK0200 3eb2c1105160ff865c01ece414d846e9 498 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 194 248 5.5E-9 T 31-10-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 TK0200 3eb2c1105160ff865c01ece414d846e9 498 Gene3D G3DSA:3.30.470.20 145 237 2.1E-15 T 31-10-2018 TK0200 3eb2c1105160ff865c01ece414d846e9 498 Gene3D G3DSA:3.30.1490.20 43 144 2.0E-18 T 31-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 TK0200 3eb2c1105160ff865c01ece414d846e9 498 SUPERFAMILY SSF56059 11 276 1.06E-51 T 31-10-2018 TK0200 3eb2c1105160ff865c01ece414d846e9 498 Pfam PF00391 PEP-utilising enzyme, mobile domain 289 356 2.0E-18 T 31-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 TK0200 3eb2c1105160ff865c01ece414d846e9 498 SUPERFAMILY SSF52009 250 361 2.88E-26 T 31-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 TK0200 3eb2c1105160ff865c01ece414d846e9 498 Gene3D G3DSA:3.50.30.10 255 363 8.7E-27 T 31-10-2018 TK2002 c39b8745c34906ae33143ec2956ce7ab 201 Gene3D G3DSA:3.90.550.10 4 198 1.5E-45 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TK2002 c39b8745c34906ae33143ec2956ce7ab 201 SUPERFAMILY SSF53448 1 185 7.93E-31 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TK2002 c39b8745c34906ae33143ec2956ce7ab 201 Pfam PF12804 MobA-like NTP transferase domain 3 143 9.1E-30 T 31-10-2018 IPR025877 MobA-like NTP transferase TK2002 c39b8745c34906ae33143ec2956ce7ab 201 Hamap MF_00316 Molybdenum cofactor guanylyltransferase [mobA]. 1 188 20.393 T 31-10-2018 IPR013482 Molybdenum cofactor guanylyltransferase GO:0003824|GO:0006777 KEGG: 00790+2.7.7.77|MetaCyc: PWY-5964|MetaCyc: PWY-7639 TK2235 5777014f77bc325e88b8bf85f577c7b2 280 Gene3D G3DSA:3.40.50.2020 17 138 6.7E-78 T 31-10-2018 TK2235 5777014f77bc325e88b8bf85f577c7b2 280 Gene3D G3DSA:3.40.50.2020 139 263 6.7E-78 T 31-10-2018 TK2235 5777014f77bc325e88b8bf85f577c7b2 280 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 17 109 8.3E-18 T 31-10-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 TK2235 5777014f77bc325e88b8bf85f577c7b2 280 SMART SM01400 1 113 3.3E-27 T 31-10-2018 TK2235 5777014f77bc325e88b8bf85f577c7b2 280 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 6 276 1.1E-87 T 31-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 TK2235 5777014f77bc325e88b8bf85f577c7b2 280 Pfam PF00156 Phosphoribosyl transferase domain 141 234 4.3E-17 T 31-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 TK2235 5777014f77bc325e88b8bf85f577c7b2 280 Hamap MF_00583_A Putative ribose-phosphate pyrophosphokinase [prs]. 1 278 35.882 T 31-10-2018 IPR037514 Ribose-phosphate pyrophosphokinase, archaea GO:0004749 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 TK2235 5777014f77bc325e88b8bf85f577c7b2 280 SUPERFAMILY SSF53271 62 270 5.36E-38 T 31-10-2018 IPR029057 Phosphoribosyltransferase-like TK0895 34cdd60eb49bddc26a16cf9b7a8ae8bb 612 Pfam PF05123 S-layer like family, N-terminal region 4 325 5.3E-87 T 31-10-2018 IPR022650 S-layer protein, N-terminal TK0895 34cdd60eb49bddc26a16cf9b7a8ae8bb 612 TIGRFAM TIGR01564 S_layer_MJ: S-layer protein 4 608 4.9E-94 T 31-10-2018 IPR006454 S-layer protein GO:0005618 TK0895 34cdd60eb49bddc26a16cf9b7a8ae8bb 612 Pfam PF05124 S-layer like family, C-terminal region 379 608 6.0E-75 T 31-10-2018 IPR022651 S-layer protein, C-terminal TK1275 d34296d83edf0122ab535fa6e16d627b 136 SUPERFAMILY SSF75471 4 99 1.83E-17 T 31-10-2018 IPR035920 YhbY-like superfamily TK1275 d34296d83edf0122ab535fa6e16d627b 136 ProDom PD010559 RNA-BINDING YHBY UPF0044 PREDICTED RNA RIBOSOMAL CONTAINING KH BINDING DOMAIN 10 94 2.0E-41 T 31-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 TK1275 d34296d83edf0122ab535fa6e16d627b 136 SMART SM01103 4 91 2.4E-25 T 31-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 TK1275 d34296d83edf0122ab535fa6e16d627b 136 Gene3D G3DSA:3.30.110.60 4 112 1.2E-20 T 31-10-2018 IPR035920 YhbY-like superfamily TK1275 d34296d83edf0122ab535fa6e16d627b 136 Pfam PF01985 CRS1 / YhbY (CRM) domain 5 91 5.6E-12 T 31-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 TK1713 eb80c88a9cc6e4b4b12d8a2df95f0278 357 Gene3D G3DSA:3.40.50.2000 180 327 7.1E-19 T 31-10-2018 TK1713 eb80c88a9cc6e4b4b12d8a2df95f0278 357 Gene3D G3DSA:3.40.50.2000 1 175 4.1E-5 T 31-10-2018 TK1713 eb80c88a9cc6e4b4b12d8a2df95f0278 357 SUPERFAMILY SSF53756 7 333 3.23E-37 T 31-10-2018 TK1713 eb80c88a9cc6e4b4b12d8a2df95f0278 357 Pfam PF00534 Glycosyl transferases group 1 177 271 3.4E-15 T 31-10-2018 IPR001296 Glycosyl transferase, family 1 TK2161 9be0704493802c08630584530f74297b 302 SMART SM00382 29 211 6.0E-15 T 31-10-2018 IPR003593 AAA+ ATPase domain TK2161 9be0704493802c08630584530f74297b 302 Gene3D G3DSA:3.40.50.300 1 272 1.9E-63 T 31-10-2018 TK2161 9be0704493802c08630584530f74297b 302 SUPERFAMILY SSF52540 3 224 2.83E-60 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK2161 9be0704493802c08630584530f74297b 302 Pfam PF00005 ABC transporter 21 166 7.2E-29 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TK1474 678ebfcc69dc1b1b0add25625f57b816 337 SUPERFAMILY SSF54211 1 183 8.35E-46 T 31-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TK1474 678ebfcc69dc1b1b0add25625f57b816 337 Pfam PF00288 GHMP kinases N terminal domain 106 172 4.4E-16 T 31-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 TK1474 678ebfcc69dc1b1b0add25625f57b816 337 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 112 123 - T 31-10-2018 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 TK1474 678ebfcc69dc1b1b0add25625f57b816 337 Gene3D G3DSA:3.30.70.890 190 322 2.1E-41 T 31-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily TK1474 678ebfcc69dc1b1b0add25625f57b816 337 Hamap MF_00217 Mevalonate kinase [mvk]. 6 330 58.686 T 31-10-2018 IPR022937 Mevalonate kinase, archaeal GO:0004496 KEGG: 00900+2.7.1.36|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-922 TK1474 678ebfcc69dc1b1b0add25625f57b816 337 PRINTS PR00959 Mevalonate kinase family signature 110 132 6.2E-29 T 31-10-2018 TK1474 678ebfcc69dc1b1b0add25625f57b816 337 PRINTS PR00959 Mevalonate kinase family signature 10 34 6.2E-29 T 31-10-2018 TK1474 678ebfcc69dc1b1b0add25625f57b816 337 PRINTS PR00959 Mevalonate kinase family signature 286 303 6.2E-29 T 31-10-2018 TK1474 678ebfcc69dc1b1b0add25625f57b816 337 PRINTS PR00959 Mevalonate kinase family signature 153 172 6.2E-29 T 31-10-2018 TK1474 678ebfcc69dc1b1b0add25625f57b816 337 SUPERFAMILY SSF55060 186 332 2.7E-37 T 31-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily TK1474 678ebfcc69dc1b1b0add25625f57b816 337 TIGRFAM TIGR00549 mevalon_kin: mevalonate kinase 10 301 4.2E-85 T 31-10-2018 IPR006205 Mevalonate kinase GO:0004496|GO:0005524|GO:0005737|GO:0008299 KEGG: 00900+2.7.1.36|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-2426168 TK1474 678ebfcc69dc1b1b0add25625f57b816 337 Pfam PF08544 GHMP kinases C terminal 248 313 2.1E-13 T 31-10-2018 IPR013750 GHMP kinase, C-terminal domain TK1474 678ebfcc69dc1b1b0add25625f57b816 337 Gene3D G3DSA:3.30.230.10 1 185 5.9E-50 T 31-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TK0504 1c19687d760e51c60910a530f9e83a07 232 Gene3D G3DSA:3.40.50.1860 107 214 1.5E-89 T 31-10-2018 TK0504 1c19687d760e51c60910a530f9e83a07 232 SUPERFAMILY SSF53681 119 227 3.14E-26 T 31-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 TK0504 1c19687d760e51c60910a530f9e83a07 232 TIGRFAM TIGR00035 asp_race: aspartate racemase 3 230 7.8E-106 T 31-10-2018 IPR004380 Aspartate racemase GO:0006520|GO:0016855 TK0504 1c19687d760e51c60910a530f9e83a07 232 Gene3D G3DSA:3.40.50.1860 6 220 1.5E-89 T 31-10-2018 TK0504 1c19687d760e51c60910a530f9e83a07 232 SUPERFAMILY SSF53681 4 117 3.6E-37 T 31-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 TK0504 1c19687d760e51c60910a530f9e83a07 232 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 81 89 - T 31-10-2018 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 TK0504 1c19687d760e51c60910a530f9e83a07 232 Pfam PF01177 Asp/Glu/Hydantoin racemase 9 222 2.2E-65 T 31-10-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 TK2231 274d941fc3b885c038db9f5acb1c7a5b 220 SUPERFAMILY SSF52540 2 219 4.85E-40 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK2231 274d941fc3b885c038db9f5acb1c7a5b 220 Pfam PF08423 Rad51 2 173 7.9E-30 T 31-10-2018 IPR013632 DNA recombination and repair protein Rad51-like, C-terminal Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579 TK2231 274d941fc3b885c038db9f5acb1c7a5b 220 TIGRFAM TIGR02237 recomb_radB: DNA repair and recombination protein RadB 9 217 1.4E-69 T 31-10-2018 IPR011939 DNA repair and recombination protein RadB GO:0003684|GO:0005524|GO:0006281|GO:0006310 TK2231 274d941fc3b885c038db9f5acb1c7a5b 220 PIRSF PIRSF003336 1 220 7.5E-103 T 31-10-2018 IPR011939 DNA repair and recombination protein RadB GO:0003684|GO:0005524|GO:0006281|GO:0006310 TK2231 274d941fc3b885c038db9f5acb1c7a5b 220 Gene3D G3DSA:3.40.50.300 7 220 3.5E-63 T 31-10-2018 TK2231 274d941fc3b885c038db9f5acb1c7a5b 220 Hamap MF_00350 DNA repair and recombination protein RadB [radB]. 8 217 38.616 T 31-10-2018 IPR011939 DNA repair and recombination protein RadB GO:0003684|GO:0005524|GO:0006281|GO:0006310 TK2231 274d941fc3b885c038db9f5acb1c7a5b 220 PRINTS PR01874 DNA repair protein radA signature 11 39 6.6E-8 T 31-10-2018 TK2231 274d941fc3b885c038db9f5acb1c7a5b 220 PRINTS PR01874 DNA repair protein radA signature 190 216 6.6E-8 T 31-10-2018 TK0984 2953c22143c329c69364e3e2d31aa1fe 215 Gene3D G3DSA:2.40.30.130 14 85 8.8E-33 T 31-10-2018 TK0984 2953c22143c329c69364e3e2d31aa1fe 215 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 170 210 4.9E-8 T 31-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 TK0984 2953c22143c329c69364e3e2d31aa1fe 215 Gene3D G3DSA:3.30.980.10 86 214 5.1E-44 T 31-10-2018 TK0984 2953c22143c329c69364e3e2d31aa1fe 215 SUPERFAMILY SSF50447 2 85 3.18E-22 T 31-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily TK0984 2953c22143c329c69364e3e2d31aa1fe 215 SMART SM00863 167 210 1.7E-8 T 31-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 TK0984 2953c22143c329c69364e3e2d31aa1fe 215 SUPERFAMILY SSF55186 86 212 1.83E-33 T 31-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 TK0984 2953c22143c329c69364e3e2d31aa1fe 215 Pfam PF01411 tRNA synthetases class II (A) 14 88 1.7E-12 T 31-10-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 TK0765 d16247ae554bcfa9cac04d042ab5439d 334 SUPERFAMILY SSF55347 140 301 2.45E-53 T 31-10-2018 TK0765 d16247ae554bcfa9cac04d042ab5439d 334 PIRSF PIRSF000149 1 318 5.2E-89 T 31-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 TK0765 d16247ae554bcfa9cac04d042ab5439d 334 SMART SM00846 3 141 2.7E-25 T 31-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 TK0765 d16247ae554bcfa9cac04d042ab5439d 334 Hamap MF_00559 Glyceraldehyde-3-phosphate dehydrogenase [gap]. 1 334 194.555 T 31-10-2018 IPR006436 Glyceraldehyde-3-phosphate dehydrogenase, type II GO:0005737|GO:0006096|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.59|KEGG: 00710+1.2.1.59 TK0765 d16247ae554bcfa9cac04d042ab5439d 334 Gene3D G3DSA:3.40.50.720 3 331 3.3E-152 T 31-10-2018 TK0765 d16247ae554bcfa9cac04d042ab5439d 334 SUPERFAMILY SSF51735 3 158 3.84E-49 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily TK0765 d16247ae554bcfa9cac04d042ab5439d 334 Gene3D G3DSA:3.30.360.10 140 301 3.3E-152 T 31-10-2018 TK0765 d16247ae554bcfa9cac04d042ab5439d 334 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 139 146 - T 31-10-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 TK0765 d16247ae554bcfa9cac04d042ab5439d 334 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 146 296 5.2E-31 T 31-10-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 TK0765 d16247ae554bcfa9cac04d042ab5439d 334 TIGRFAM TIGR01546 GAPDH-II_archae: glyceraldehyde-3-phosphate dehydrogenase, type II 5 333 1.2E-183 T 31-10-2018 IPR006436 Glyceraldehyde-3-phosphate dehydrogenase, type II GO:0005737|GO:0006096|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.59|KEGG: 00710+1.2.1.59 TK0765 d16247ae554bcfa9cac04d042ab5439d 334 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 3 118 1.6E-13 T 31-10-2018 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 TK1880 55de4061c36daf743a35a3d45c721efb 469 SUPERFAMILY SSF52210 136 298 1.83E-42 T 31-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TK1880 55de4061c36daf743a35a3d45c721efb 469 SUPERFAMILY SSF51735 6 135 2.19E-37 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily TK1880 55de4061c36daf743a35a3d45c721efb 469 SMART SM00881 9 107 1.0E-38 T 31-10-2018 IPR003781 CoA-binding GO:0048037 TK1880 55de4061c36daf743a35a3d45c721efb 469 Pfam PF13380 CoA binding domain 13 139 2.1E-23 T 31-10-2018 IPR003781 CoA-binding GO:0048037 TK1880 55de4061c36daf743a35a3d45c721efb 469 Gene3D G3DSA:3.40.50.261 302 466 2.9E-44 T 31-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TK1880 55de4061c36daf743a35a3d45c721efb 469 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 161 297 2.2E-57 T 31-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain TK1880 55de4061c36daf743a35a3d45c721efb 469 Gene3D G3DSA:3.40.50.720 4 134 2.5E-44 T 31-10-2018 TK1880 55de4061c36daf743a35a3d45c721efb 469 SUPERFAMILY SSF52210 304 463 7.2E-35 T 31-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TK1880 55de4061c36daf743a35a3d45c721efb 469 Gene3D G3DSA:3.40.50.261 136 300 4.4E-60 T 31-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TK1031 126d33fe3f99142327703868df997645 594 SUPERFAMILY SSF52540 97 286 1.18E-33 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK1031 126d33fe3f99142327703868df997645 594 SUPERFAMILY SSF54862 5 125 9.86E-24 T 31-10-2018 TK1031 126d33fe3f99142327703868df997645 594 SMART SM00382 99 289 1.1E-8 T 31-10-2018 IPR003593 AAA+ ATPase domain TK1031 126d33fe3f99142327703868df997645 594 SMART SM00382 366 534 6.1E-12 T 31-10-2018 IPR003593 AAA+ ATPase domain TK1031 126d33fe3f99142327703868df997645 594 ProSitePatterns PS00211 ABC transporters family signature. 212 226 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TK1031 126d33fe3f99142327703868df997645 594 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 52 63 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TK1031 126d33fe3f99142327703868df997645 594 Pfam PF00005 ABC transporter 97 239 2.3E-18 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TK1031 126d33fe3f99142327703868df997645 594 PRINTS PR01868 ABC transporter family E signature 49 73 7.5E-63 T 31-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 TK1031 126d33fe3f99142327703868df997645 594 PRINTS PR01868 ABC transporter family E signature 151 177 7.5E-63 T 31-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 TK1031 126d33fe3f99142327703868df997645 594 PRINTS PR01868 ABC transporter family E signature 135 151 7.5E-63 T 31-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 TK1031 126d33fe3f99142327703868df997645 594 PRINTS PR01868 ABC transporter family E signature 21 36 7.5E-63 T 31-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 TK1031 126d33fe3f99142327703868df997645 594 PRINTS PR01868 ABC transporter family E signature 104 129 7.5E-63 T 31-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 TK1031 126d33fe3f99142327703868df997645 594 PRINTS PR01868 ABC transporter family E signature 76 96 7.5E-63 T 31-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 TK1031 126d33fe3f99142327703868df997645 594 SUPERFAMILY SSF52540 340 532 1.97E-40 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK1031 126d33fe3f99142327703868df997645 594 Gene3D G3DSA:3.40.50.300 1 327 3.7E-102 T 31-10-2018 TK1031 126d33fe3f99142327703868df997645 594 Pfam PF00005 ABC transporter 364 485 6.8E-21 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TK1031 126d33fe3f99142327703868df997645 594 Gene3D G3DSA:3.40.50.300 328 592 2.0E-66 T 31-10-2018 TK1031 126d33fe3f99142327703868df997645 594 Pfam PF00037 4Fe-4S binding domain 46 68 7.1E-7 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TK1031 126d33fe3f99142327703868df997645 594 Pfam PF04068 Possible Fer4-like domain in RNase L inhibitor, RLI 3 33 5.7E-11 T 31-10-2018 IPR007209 RNase L inhibitor RLI, possible metal-binding domain TK1740 e54e4a62266ce463099abd5d3b43dc98 405 SUPERFAMILY SSF50998 19 298 9.68E-11 T 31-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily TK1740 e54e4a62266ce463099abd5d3b43dc98 405 Gene3D G3DSA:2.130.10.10 22 324 2.2E-10 T 31-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 TK2169 08341eb4427bca69c58791cbd4b4837b 455 PIRSF PIRSF004919 1 455 9.2E-163 T 31-10-2018 IPR025502 TldD TK2169 08341eb4427bca69c58791cbd4b4837b 455 Gene3D G3DSA:3.30.2290.10 1 195 6.9E-18 T 31-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal TK2169 08341eb4427bca69c58791cbd4b4837b 455 Pfam PF01523 Putative modulator of DNA gyrase 21 309 6.4E-65 T 31-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 TK2169 08341eb4427bca69c58791cbd4b4837b 455 SUPERFAMILY SSF111283 1 449 6.28E-114 T 31-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 TK1542 f3bae4c32c706119e1dace3a0d4edc63 346 Pfam PF00297 Ribosomal protein L3 3 346 7.1E-91 T 31-10-2018 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TK1542 f3bae4c32c706119e1dace3a0d4edc63 346 Gene3D G3DSA:2.40.30.10 39 326 6.8E-123 T 31-10-2018 TK1542 f3bae4c32c706119e1dace3a0d4edc63 346 Hamap MF_01325_A 50S ribosomal protein L3 [rplC]. 1 346 50.217 T 31-10-2018 IPR019928 Ribosomal protein L3, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 TK1542 f3bae4c32c706119e1dace3a0d4edc63 346 TIGRFAM TIGR03626 L3_arch: ribosomal protein uL3 5 345 1.7E-136 T 31-10-2018 IPR019928 Ribosomal protein L3, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 TK1542 f3bae4c32c706119e1dace3a0d4edc63 346 Gene3D G3DSA:4.10.960.10 6 257 6.8E-123 T 31-10-2018 TK1542 f3bae4c32c706119e1dace3a0d4edc63 346 ProSitePatterns PS00474 Ribosomal protein L3 signature. 193 216 - T 31-10-2018 IPR019926 Ribosomal protein L3, conserved site TK1542 f3bae4c32c706119e1dace3a0d4edc63 346 Gene3D G3DSA:3.30.1430.10 77 188 6.8E-123 T 31-10-2018 TK1542 f3bae4c32c706119e1dace3a0d4edc63 346 SUPERFAMILY SSF50447 3 346 1.24E-96 T 31-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily TK1021 4a59a82d6599ed9bc437a352836ee5c2 804 SMART SM00278 747 766 850.0 T 31-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 TK1021 4a59a82d6599ed9bc437a352836ee5c2 804 SMART SM00278 779 798 0.021 T 31-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 TK1021 4a59a82d6599ed9bc437a352836ee5c2 804 Gene3D G3DSA:3.40.50.300 210 479 9.8E-101 T 31-10-2018 TK1021 4a59a82d6599ed9bc437a352836ee5c2 804 Gene3D G3DSA:1.10.150.20 734 803 1.1E-21 T 31-10-2018 TK1021 4a59a82d6599ed9bc437a352836ee5c2 804 Gene3D G3DSA:3.40.50.10130 592 733 1.2E-53 T 31-10-2018 TK1021 4a59a82d6599ed9bc437a352836ee5c2 804 SUPERFAMILY SSF52540 53 481 8.63E-60 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK1021 4a59a82d6599ed9bc437a352836ee5c2 804 SMART SM00490 373 462 4.6E-25 T 31-10-2018 IPR001650 Helicase, C-terminal TK1021 4a59a82d6599ed9bc437a352836ee5c2 804 Pfam PF00270 DEAD/DEAH box helicase 15 170 6.6E-20 T 31-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 TK1021 4a59a82d6599ed9bc437a352836ee5c2 804 SMART SM00891 596 676 4.4E-32 T 31-10-2018 IPR006166 ERCC4 domain GO:0003677|GO:0004518 Reactome: R-HSA-6783310 TK1021 4a59a82d6599ed9bc437a352836ee5c2 804 SUPERFAMILY SSF52980 595 724 3.22E-38 T 31-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 TK1021 4a59a82d6599ed9bc437a352836ee5c2 804 Gene3D G3DSA:1.20.1320.20 213 339 9.8E-101 T 31-10-2018 TK1021 4a59a82d6599ed9bc437a352836ee5c2 804 Pfam PF02732 ERCC4 domain 599 717 1.3E-29 T 31-10-2018 IPR006166 ERCC4 domain GO:0003677|GO:0004518 Reactome: R-HSA-6783310 TK1021 4a59a82d6599ed9bc437a352836ee5c2 804 Pfam PF12826 Helix-hairpin-helix motif 751 797 1.4E-9 T 31-10-2018 TK1021 4a59a82d6599ed9bc437a352836ee5c2 804 Pfam PF00271 Helicase conserved C-terminal domain 345 461 3.7E-23 T 31-10-2018 IPR001650 Helicase, C-terminal TK1021 4a59a82d6599ed9bc437a352836ee5c2 804 SMART SM00487 7 202 6.5E-31 T 31-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TK1021 4a59a82d6599ed9bc437a352836ee5c2 804 Gene3D G3DSA:3.40.50.300 3 200 2.7E-73 T 31-10-2018 TK1021 4a59a82d6599ed9bc437a352836ee5c2 804 SUPERFAMILY SSF47781 734 799 1.56E-15 T 31-10-2018 IPR010994 RuvA domain 2-like TK0636 f99c1b97f7def0ec166b239f9179b0cb 207 Pfam PF04509 CheC-like family 110 145 2.3E-9 T 31-10-2018 IPR007597 CheC-like protein GO:0016787 TK0636 f99c1b97f7def0ec166b239f9179b0cb 207 Pfam PF04509 CheC-like family 15 49 8.8E-5 T 31-10-2018 IPR007597 CheC-like protein GO:0016787 TK0636 f99c1b97f7def0ec166b239f9179b0cb 207 Gene3D G3DSA:3.40.1550.10 9 203 1.4E-54 T 31-10-2018 IPR028976 CheC-like superfamily TK0636 f99c1b97f7def0ec166b239f9179b0cb 207 SUPERFAMILY SSF103039 9 202 1.7E-48 T 31-10-2018 IPR028976 CheC-like superfamily TK1812 fd2623f0aaf75d94e543131bbe84d144 81 Pfam PF01998 Protein of unknown function DUF131 31 73 6.1E-14 T 31-10-2018 IPR002849 Protein of unknown function DUF131 TK1443 6a2c2124085c3e83184b1cae3f186758 335 Gene3D G3DSA:3.30.360.10 142 311 3.5E-117 T 31-10-2018 TK1443 6a2c2124085c3e83184b1cae3f186758 335 PIRSF PIRSF000148 1 334 3.7E-91 T 31-10-2018 TK1443 6a2c2124085c3e83184b1cae3f186758 335 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 152 314 1.1E-27 T 31-10-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0005737|GO:0008652|GO:0016620|GO:0046983 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 TK1443 6a2c2124085c3e83184b1cae3f186758 335 Gene3D G3DSA:3.40.50.720 2 327 3.5E-117 T 31-10-2018 TK1443 6a2c2124085c3e83184b1cae3f186758 335 TIGRFAM TIGR00978 asd_EA: aspartate-semialdehyde dehydrogenase 1 330 2.3E-135 T 31-10-2018 IPR005676 Aspartate-semialdehyde dehydrogenase, peptidoglycan lacking GO:0050661|GO:0055114 TK1443 6a2c2124085c3e83184b1cae3f186758 335 SMART SM00859 2 123 2.7E-31 T 31-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 TK1443 6a2c2124085c3e83184b1cae3f186758 335 SUPERFAMILY SSF51735 1 168 3.29E-39 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily TK1443 6a2c2124085c3e83184b1cae3f186758 335 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 2 121 2.9E-28 T 31-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 TK1443 6a2c2124085c3e83184b1cae3f186758 335 SUPERFAMILY SSF55347 140 316 4.46E-36 T 31-10-2018 TK0048 3ce1d10a5099bc8cb90a07e79d4fdea3 540 Gene3D G3DSA:1.10.390.40 83 158 1.9E-58 T 31-10-2018 TK0048 3ce1d10a5099bc8cb90a07e79d4fdea3 540 Gene3D G3DSA:3.30.450.370 50 256 1.9E-58 T 31-10-2018 TK0048 3ce1d10a5099bc8cb90a07e79d4fdea3 540 SUPERFAMILY SSF52540 141 523 4.61E-58 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK0048 3ce1d10a5099bc8cb90a07e79d4fdea3 540 Pfam PF00437 Type II/IV secretion system protein 161 406 4.6E-47 T 31-10-2018 IPR001482 Type II/IV secretion system protein TK0048 3ce1d10a5099bc8cb90a07e79d4fdea3 540 Gene3D G3DSA:3.40.50.300 259 536 3.6E-89 T 31-10-2018 TK0449 82299e1db4a12fa47ef0c2c1160a9867 220 SUPERFAMILY SSF109604 36 114 1.57E-6 T 31-10-2018 TK0449 82299e1db4a12fa47ef0c2c1160a9867 220 Pfam PF01966 HD domain 17 186 4.4E-14 T 31-10-2018 IPR006674 HD domain TK0449 82299e1db4a12fa47ef0c2c1160a9867 220 Gene3D G3DSA:1.10.3210.30 1 179 1.1E-19 T 31-10-2018 IPR038257 CRISPR-associated Cas3-type HD domain superfamily TK0449 82299e1db4a12fa47ef0c2c1160a9867 220 TIGRFAM TIGR01596 cas3_HD: CRISPR-associated endonuclease Cas3-HD 38 185 6.1E-13 T 31-10-2018 IPR006483 CRISPR-associated Cas3-type HD domain TK0140 32627510016fc939f6daa6753556f8d4 452 Pfam PF01637 ATPase domain predominantly from Archaea 5 199 8.9E-16 T 31-10-2018 IPR011579 ATPase domain GO:0005524 TK0140 32627510016fc939f6daa6753556f8d4 452 SUPERFAMILY SSF46785 239 314 9.63E-6 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TK0140 32627510016fc939f6daa6753556f8d4 452 Pfam PF03008 Archaea bacterial proteins of unknown function 306 403 1.0E-29 T 31-10-2018 IPR004256 Domain of unknown function DUF234, DEXX-box ATPase C-terminal TK0140 32627510016fc939f6daa6753556f8d4 452 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 235 300 1.8E-6 T 31-10-2018 IPR002831 Transcription regulator TrmB, N-terminal TK0140 32627510016fc939f6daa6753556f8d4 452 Gene3D G3DSA:3.40.50.300 2 169 2.3E-28 T 31-10-2018 TK0140 32627510016fc939f6daa6753556f8d4 452 SUPERFAMILY SSF52540 3 233 9.76E-32 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK2203 d2c4c8c5db15097fee4b269f636ab31b 262 SUPERFAMILY SSF53213 6 259 7.98E-24 T 31-10-2018 TK2203 d2c4c8c5db15097fee4b269f636ab31b 262 Gene3D G3DSA:3.40.830.10 1 262 4.4E-70 T 31-10-2018 TK2203 d2c4c8c5db15097fee4b269f636ab31b 262 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 8 254 5.8E-11 T 31-10-2018 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 TK0030 5cbbb2852ef715ada19bb3f2ef95d7f4 189 SUPERFAMILY SSF102198 2 188 1.26E-54 T 31-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 TK0030 5cbbb2852ef715ada19bb3f2ef95d7f4 189 Gene3D G3DSA:3.50.30.50 1 188 5.0E-57 T 31-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 TK0030 5cbbb2852ef715ada19bb3f2ef95d7f4 189 Pfam PF04199 Putative cyclase 3 134 3.6E-23 T 31-10-2018 IPR007325 Kynurenine formamidase/cyclase-like GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 TK0535 df4c7082eb56fbebbb9d7f8a05c648cb 249 TIGRFAM TIGR00590 pcna: proliferating cell nuclear antigen (pcna) 3 249 9.7E-40 T 31-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 TK0535 df4c7082eb56fbebbb9d7f8a05c648cb 249 Gene3D G3DSA:3.70.10.10 2 242 8.2E-79 T 31-10-2018 TK0535 df4c7082eb56fbebbb9d7f8a05c648cb 249 Pfam PF00705 Proliferating cell nuclear antigen, N-terminal domain 3 110 4.0E-17 T 31-10-2018 IPR022648 Proliferating cell nuclear antigen, PCNA, N-terminal GO:0003677|GO:0006275 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 TK0535 df4c7082eb56fbebbb9d7f8a05c648cb 249 SUPERFAMILY SSF55979 3 117 4.26E-33 T 31-10-2018 TK0535 df4c7082eb56fbebbb9d7f8a05c648cb 249 SUPERFAMILY SSF55979 124 247 1.84E-31 T 31-10-2018 TK0535 df4c7082eb56fbebbb9d7f8a05c648cb 249 Pfam PF02747 Proliferating cell nuclear antigen, C-terminal domain 126 245 4.2E-10 T 31-10-2018 IPR022649 Proliferating cell nuclear antigen, PCNA, C-terminal GO:0003677|GO:0006275 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 TK0535 df4c7082eb56fbebbb9d7f8a05c648cb 249 ProSitePatterns PS01251 Proliferating cell nuclear antigen signature 1. 35 58 - T 31-10-2018 IPR022659 Proliferating cell nuclear antigen, PCNA, conserved site Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 TK0535 df4c7082eb56fbebbb9d7f8a05c648cb 249 Hamap MF_00317 DNA polymerase sliding clamp [pcn]. 3 247 32.936 T 31-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 TK0535 df4c7082eb56fbebbb9d7f8a05c648cb 249 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 35 53 3.9E-18 T 31-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 TK0535 df4c7082eb56fbebbb9d7f8a05c648cb 249 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 57 81 3.9E-18 T 31-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 TK0535 df4c7082eb56fbebbb9d7f8a05c648cb 249 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 107 129 3.9E-18 T 31-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 TK0535 df4c7082eb56fbebbb9d7f8a05c648cb 249 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 11 30 3.9E-18 T 31-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 TK0535 df4c7082eb56fbebbb9d7f8a05c648cb 249 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 233 249 3.9E-18 T 31-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 TK0535 df4c7082eb56fbebbb9d7f8a05c648cb 249 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 195 209 3.9E-18 T 31-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 TK0233 6944f9d9ed3f16fb36022fe5f263fd24 193 Gene3D G3DSA:3.40.630.30 2 189 1.0E-48 T 31-10-2018 TK0233 6944f9d9ed3f16fb36022fe5f263fd24 193 Pfam PF13302 Acetyltransferase (GNAT) domain 18 148 5.0E-30 T 31-10-2018 IPR000182 GNAT domain TK0233 6944f9d9ed3f16fb36022fe5f263fd24 193 SUPERFAMILY SSF55729 2 172 2.52E-44 T 31-10-2018 IPR016181 Acyl-CoA N-acyltransferase TK0956 d7d3a50f93d3982d8f71288c4abe25de 88 SUPERFAMILY SSF46785 10 50 8.17E-7 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TK0956 d7d3a50f93d3982d8f71288c4abe25de 88 Pfam PF13412 Winged helix-turn-helix DNA-binding 10 46 2.0E-5 T 31-10-2018 TK0956 d7d3a50f93d3982d8f71288c4abe25de 88 Gene3D G3DSA:1.10.10.10 1 58 4.1E-7 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TK1049 306de928d7d91938ee8b3814a3d07a00 741 Gene3D G3DSA:3.40.50.620 5 316 7.0E-144 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TK1049 306de928d7d91938ee8b3814a3d07a00 741 Gene3D G3DSA:2.170.220.10 98 252 7.0E-144 T 31-10-2018 TK1049 306de928d7d91938ee8b3814a3d07a00 741 Gene3D G3DSA:2.40.50.140 635 741 3.1E-44 T 31-10-2018 TK1049 306de928d7d91938ee8b3814a3d07a00 741 Pfam PF01588 Putative tRNA binding domain 647 738 7.9E-32 T 31-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 TK1049 306de928d7d91938ee8b3814a3d07a00 741 SUPERFAMILY SSF52374 3 394 5.91E-106 T 31-10-2018 TK1049 306de928d7d91938ee8b3814a3d07a00 741 SUPERFAMILY SSF57770 139 173 1.02E-10 T 31-10-2018 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 TK1049 306de928d7d91938ee8b3814a3d07a00 741 TIGRFAM TIGR00399 metG_C_term: methionine--tRNA ligase, beta subunit 617 741 3.3E-40 T 31-10-2018 IPR004495 Methionyl-tRNA synthetase, beta subunit, C-terminal GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 TK1049 306de928d7d91938ee8b3814a3d07a00 741 Pfam PF09334 tRNA synthetases class I (M) 4 409 4.9E-160 T 31-10-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 TK1049 306de928d7d91938ee8b3814a3d07a00 741 SUPERFAMILY SSF50249 640 740 1.2E-37 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold TK1049 306de928d7d91938ee8b3814a3d07a00 741 Gene3D G3DSA:1.10.730.10 398 548 4.3E-105 T 31-10-2018 TK1049 306de928d7d91938ee8b3814a3d07a00 741 Pfam PF08264 Anticodon-binding domain of tRNA 430 523 9.9E-15 T 31-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 TK1049 306de928d7d91938ee8b3814a3d07a00 741 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 11 22 - T 31-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 TK1049 306de928d7d91938ee8b3814a3d07a00 741 PRINTS PR01041 Methionyl-tRNA synthetase signature 6 19 1.1E-32 T 31-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 TK1049 306de928d7d91938ee8b3814a3d07a00 741 PRINTS PR01041 Methionyl-tRNA synthetase signature 87 98 1.1E-32 T 31-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 TK1049 306de928d7d91938ee8b3814a3d07a00 741 PRINTS PR01041 Methionyl-tRNA synthetase signature 396 407 1.1E-32 T 31-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 TK1049 306de928d7d91938ee8b3814a3d07a00 741 PRINTS PR01041 Methionyl-tRNA synthetase signature 294 309 1.1E-32 T 31-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 TK1049 306de928d7d91938ee8b3814a3d07a00 741 PRINTS PR01041 Methionyl-tRNA synthetase signature 252 263 1.1E-32 T 31-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 TK1049 306de928d7d91938ee8b3814a3d07a00 741 PRINTS PR01041 Methionyl-tRNA synthetase signature 39 53 1.1E-32 T 31-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 TK1049 306de928d7d91938ee8b3814a3d07a00 741 Gene3D G3DSA:1.10.730.10 341 582 4.3E-105 T 31-10-2018 TK1049 306de928d7d91938ee8b3814a3d07a00 741 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 5 549 2.5E-177 T 31-10-2018 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 TK1049 306de928d7d91938ee8b3814a3d07a00 741 Hamap MF_00098 Methionine--tRNA ligase [metG]. 2 560 42.876 T 31-10-2018 IPR023458 Methionine-tRNA ligase, type 1 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 TK1049 306de928d7d91938ee8b3814a3d07a00 741 SUPERFAMILY SSF47323 398 563 1.76E-46 T 31-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 TK2021 6236d4adcbf999e94060eecb506e91ec 295 ProSitePatterns PS01215 Mrp family signature. 146 162 - T 31-10-2018 IPR000808 Mrp, conserved site GO:0005524 TK2021 6236d4adcbf999e94060eecb506e91ec 295 SUPERFAMILY SSF52540 17 265 1.95E-59 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK2021 6236d4adcbf999e94060eecb506e91ec 295 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 30 281 9.5E-96 T 31-10-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 TK2021 6236d4adcbf999e94060eecb506e91ec 295 Hamap MF_02040 Iron-sulfur cluster carrier protein. 20 282 37.441 T 31-10-2018 IPR019591 Mrp/NBP35 ATP-binding protein TK2021 6236d4adcbf999e94060eecb506e91ec 295 Gene3D G3DSA:3.40.50.300 17 281 2.8E-82 T 31-10-2018 TK0775 56f65e8063e9a646e7dff0560ac3aef8 337 Gene3D G3DSA:3.40.630.10 11 332 2.4E-114 T 31-10-2018 TK0775 56f65e8063e9a646e7dff0560ac3aef8 337 Pfam PF05343 M42 glutamyl aminopeptidase 48 327 1.2E-71 T 31-10-2018 IPR008007 Peptidase M42 TK0775 56f65e8063e9a646e7dff0560ac3aef8 337 PIRSF PIRSF001123 1 335 6.2E-38 T 31-10-2018 IPR008007 Peptidase M42 TK0775 56f65e8063e9a646e7dff0560ac3aef8 337 Gene3D G3DSA:2.40.30.40 70 164 2.4E-114 T 31-10-2018 IPR023367 Peptidase M42, domain 2 TK0775 56f65e8063e9a646e7dff0560ac3aef8 337 SUPERFAMILY SSF53187 2 334 1.11E-48 T 31-10-2018 TK0775 56f65e8063e9a646e7dff0560ac3aef8 337 SUPERFAMILY SSF101821 67 178 5.19E-27 T 31-10-2018 TK1681 f6d66e53ba115962dcb3e0a5b3d08b92 299 Hamap MF_01406 UPF0282 protein . 1 286 39.163 T 31-10-2018 IPR014426 Uncharacterised protein family UPF0282, hydrolase, metallo-beta-lactamase TK1681 f6d66e53ba115962dcb3e0a5b3d08b92 299 SUPERFAMILY SSF56281 1 262 1.17E-19 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TK1681 f6d66e53ba115962dcb3e0a5b3d08b92 299 Gene3D G3DSA:3.60.15.10 7 271 6.8E-17 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TK1681 f6d66e53ba115962dcb3e0a5b3d08b92 299 PIRSF PIRSF004944 1 299 3.2E-117 T 31-10-2018 IPR014426 Uncharacterised protein family UPF0282, hydrolase, metallo-beta-lactamase TK1681 f6d66e53ba115962dcb3e0a5b3d08b92 299 Pfam PF13483 Beta-lactamase superfamily domain 19 191 1.0E-7 T 31-10-2018 TK1412 a4107639b4ce88a90b05d6aa22261720 424 SUPERFAMILY SSF102114 158 376 6.15E-39 T 31-10-2018 TK1412 a4107639b4ce88a90b05d6aa22261720 424 Pfam PF04055 Radical SAM superfamily 168 338 2.1E-25 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TK1412 a4107639b4ce88a90b05d6aa22261720 424 Gene3D G3DSA:3.40.50.280 3 128 9.0E-26 T 31-10-2018 TK1412 a4107639b4ce88a90b05d6aa22261720 424 Pfam PF02310 B12 binding domain 17 112 2.7E-9 T 31-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 TK1412 a4107639b4ce88a90b05d6aa22261720 424 TIGRFAM TIGR04013 B12_SAM_MJ_1487: B12-binding domain/radical SAM domain protein, MJ_1487 family 4 392 6.0E-142 T 31-10-2018 IPR023980 Conserved hypothetical protein CHP04013, B12-binding/radical SAM-type TK1412 a4107639b4ce88a90b05d6aa22261720 424 SMART SM00729 164 382 1.4E-46 T 31-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TK1412 a4107639b4ce88a90b05d6aa22261720 424 Gene3D G3DSA:3.80.30.20 163 389 6.8E-37 T 31-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe TK0556 a10a557eb7520e70086408b2edb5f95a 356 Pfam PF01008 Initiation factor 2 subunit family 55 341 1.6E-81 T 31-10-2018 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 TK0556 a10a557eb7520e70086408b2edb5f95a 356 Hamap MF_01678 Putative methylthioribose-1-phosphate isomerase [mtnA]. 13 353 39.874 T 31-10-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 TK0556 a10a557eb7520e70086408b2edb5f95a 356 Gene3D G3DSA:1.20.120.420 11 156 3.8E-45 T 31-10-2018 IPR027363 Methylthioribose-1-phosphate isomerase, N-terminal KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 TK0556 a10a557eb7520e70086408b2edb5f95a 356 SUPERFAMILY SSF100950 12 349 5.16E-115 T 31-10-2018 IPR037171 NagB/RpiA transferase-like TK0556 a10a557eb7520e70086408b2edb5f95a 356 TIGRFAM TIGR00512 salvage_mtnA: S-methyl-5-thioribose-1-phosphate isomerase 15 341 2.0E-127 T 31-10-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 TK0556 a10a557eb7520e70086408b2edb5f95a 356 Gene3D G3DSA:3.40.50.10470 159 356 1.5E-60 T 31-10-2018 TK0556 a10a557eb7520e70086408b2edb5f95a 356 TIGRFAM TIGR00524 eIF-2B_rel: eIF-2B alpha/beta/delta-related uncharacterized proteins 42 342 5.0E-114 T 31-10-2018 IPR011559 Initiation factor 2B alpha/beta/delta GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 TK0513 bc5b242a496e9f83a001730a95a1017f 288 SUPERFAMILY SSF48239 8 251 2.36E-19 T 31-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid TK0513 bc5b242a496e9f83a001730a95a1017f 288 PIRSF PIRSF016175 7 287 1.8E-143 T 31-10-2018 IPR016648 Uncharacterised conserved protein UCP016175, prenyltransferase beta-subunit-related TK0899 4e7bb26989839a594c2500f1352c64e4 279 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 14 267 46.818 T 31-10-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 TK0899 4e7bb26989839a594c2500f1352c64e4 279 Pfam PF00398 Ribosomal RNA adenine dimethylase 17 226 1.9E-53 T 31-10-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm TK0899 4e7bb26989839a594c2500f1352c64e4 279 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 46 73 - T 31-10-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 TK0899 4e7bb26989839a594c2500f1352c64e4 279 Gene3D G3DSA:1.10.8.100 195 272 4.1E-9 T 31-10-2018 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201|Reactome: R-HSA-6793080 TK0899 4e7bb26989839a594c2500f1352c64e4 279 SUPERFAMILY SSF53335 11 268 9.36E-62 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TK0899 4e7bb26989839a594c2500f1352c64e4 279 SMART SM00650 30 193 7.0E-77 T 31-10-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 TK0899 4e7bb26989839a594c2500f1352c64e4 279 Gene3D G3DSA:3.40.50.150 2 193 9.8E-64 T 31-10-2018 TK0899 4e7bb26989839a594c2500f1352c64e4 279 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 15 264 6.7E-78 T 31-10-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 TK1520 c4a82ae736b97958bc95c4493ee632e5 155 Gene3D G3DSA:1.10.15.30 60 114 1.7E-56 T 31-10-2018 IPR023106 Ribosomal protein L30, central domain, archaeal type TK1520 c4a82ae736b97958bc95c4493ee632e5 155 ProSitePatterns PS00634 Ribosomal protein L30 signature. 22 54 - T 31-10-2018 IPR018038 Ribosomal protein L30, conserved site TK1520 c4a82ae736b97958bc95c4493ee632e5 155 Pfam PF00327 Ribosomal protein L30p/L7e 6 54 1.5E-16 T 31-10-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain TK1520 c4a82ae736b97958bc95c4493ee632e5 155 SUPERFAMILY SSF55129 5 155 3.14E-50 T 31-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily TK1520 c4a82ae736b97958bc95c4493ee632e5 155 Gene3D G3DSA:3.30.1390.20 5 143 1.7E-56 T 31-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily TK1520 c4a82ae736b97958bc95c4493ee632e5 155 TIGRFAM TIGR01309 uL30_arch: ribosomal protein uL30 4 155 4.4E-63 T 31-10-2018 IPR005997 Ribosomal protein L30, archaeal GO:0003735|GO:0006412|GO:0015934 TK1520 c4a82ae736b97958bc95c4493ee632e5 155 Hamap MF_01371_A 50S ribosomal protein L30 [rpmD]. 1 155 83.331 T 31-10-2018 IPR005997 Ribosomal protein L30, archaeal GO:0003735|GO:0006412|GO:0015934 TK0338 b1138d8c74891d0f5ab6a45b8573fec6 177 Gene3D G3DSA:3.40.50.300 1 177 2.8E-60 T 31-10-2018 TK0338 b1138d8c74891d0f5ab6a45b8573fec6 177 Hamap MF_00039 Putative adenylate kinase. 1 160 25.953 T 31-10-2018 IPR020618 Adenylate kinase isoenzyme 6 GO:0004017|GO:0005524 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 TK0338 b1138d8c74891d0f5ab6a45b8573fec6 177 Pfam PF13238 AAA domain 3 116 3.8E-23 T 31-10-2018 TK0338 b1138d8c74891d0f5ab6a45b8573fec6 177 SUPERFAMILY SSF52540 1 154 6.88E-27 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK0275 7e03e2c02c48088e21f761b32151d585 362 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 199 235 - T 31-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TK0275 7e03e2c02c48088e21f761b32151d585 362 Hamap MF_02084 [LysW]-aminoadipate semialdehyde/glutamate semialdehyde transaminase [lysJ]. 1 359 44.235 T 31-10-2018 IPR037537 [LysW]-aminoadipate semialdehyde/glutamate semialdehyde transaminase GO:0008483 TK0275 7e03e2c02c48088e21f761b32151d585 362 Gene3D G3DSA:3.40.640.10 42 276 1.5E-125 T 31-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TK0275 7e03e2c02c48088e21f761b32151d585 362 SUPERFAMILY SSF53383 8 360 1.77E-109 T 31-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TK0275 7e03e2c02c48088e21f761b32151d585 362 TIGRFAM TIGR00707 argD: transaminase, acetylornithine/succinylornithine family 4 358 4.8E-140 T 31-10-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 TK0275 7e03e2c02c48088e21f761b32151d585 362 Pfam PF00202 Aminotransferase class-III 9 356 1.7E-96 T 31-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TK0275 7e03e2c02c48088e21f761b32151d585 362 PIRSF PIRSF000521 146 361 5.7E-27 T 31-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TK0275 7e03e2c02c48088e21f761b32151d585 362 PIRSF PIRSF000521 7 109 1.6E-5 T 31-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TK0275 7e03e2c02c48088e21f761b32151d585 362 PIRSF PIRSF000521 102 135 0.0089 T 31-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TK0275 7e03e2c02c48088e21f761b32151d585 362 Gene3D G3DSA:3.90.1150.10 9 348 1.5E-125 T 31-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TK1633 c07b3cc7c16bb4729756ad56e8074ab6 272 SUPERFAMILY SSF55666 187 269 1.96E-23 T 31-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TK1633 c07b3cc7c16bb4729756ad56e8074ab6 272 SUPERFAMILY SSF54211 12 215 2.63E-54 T 31-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TK1633 c07b3cc7c16bb4729756ad56e8074ab6 272 Hamap MF_00622 Exosome complex component Rrp42 [rrp42]. 3 268 46.124 T 31-10-2018 IPR020869 Exosome complex component Rrp42, archaea GO:0000178|GO:0006401 TK1633 c07b3cc7c16bb4729756ad56e8074ab6 272 Pfam PF01138 3' exoribonuclease family, domain 1 33 167 3.6E-27 T 31-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TK1633 c07b3cc7c16bb4729756ad56e8074ab6 272 Gene3D G3DSA:3.30.230.70 1 271 1.4E-89 T 31-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TK1633 c07b3cc7c16bb4729756ad56e8074ab6 272 Pfam PF03725 3' exoribonuclease family, domain 2 191 256 1.4E-14 T 31-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TK1232 aa4d587fe25511af4873987a2aed862a 367 Pfam PF04007 Protein of unknown function (DUF354) 1 318 1.3E-97 T 31-10-2018 IPR007152 Protein of unknown function DUF354 TK1232 aa4d587fe25511af4873987a2aed862a 367 PIRSF PIRSF005357 1 345 6.7E-118 T 31-10-2018 IPR007152 Protein of unknown function DUF354 TK1232 aa4d587fe25511af4873987a2aed862a 367 SUPERFAMILY SSF53756 1 319 1.63E-25 T 31-10-2018 TK0042 92d09b74e714c1dd06330811d4709ac3 275 TIGRFAM TIGR02537 arch_flag_Nterm: archaeal flagellin N-terminal-like domain 2 25 1.4E-5 T 31-10-2018 IPR013373 Flagellin/pilin, N-terminal TK0042 92d09b74e714c1dd06330811d4709ac3 275 Pfam PF01917 Archaebacterial flagellin 4 261 6.5E-40 T 31-10-2018 IPR002774 Flagellin, archaea GO:0005198|GO:0006928 TK1210 49b08b864ae4eec14dff26491c48b6fb 153 Pfam PF13404 AsnC-type helix-turn-helix domain 7 47 8.8E-18 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TK1210 49b08b864ae4eec14dff26491c48b6fb 153 SUPERFAMILY SSF54909 67 144 1.17E-17 T 31-10-2018 IPR011008 Dimeric alpha-beta barrel TK1210 49b08b864ae4eec14dff26491c48b6fb 153 Gene3D G3DSA:1.10.10.10 5 58 2.3E-22 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TK1210 49b08b864ae4eec14dff26491c48b6fb 153 SUPERFAMILY SSF46785 6 75 5.94E-17 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TK1210 49b08b864ae4eec14dff26491c48b6fb 153 Pfam PF01037 Lrp/AsnC ligand binding domain 74 142 9.5E-16 T 31-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain TK1210 49b08b864ae4eec14dff26491c48b6fb 153 SMART SM00344 7 113 3.1E-45 T 31-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 TK1210 49b08b864ae4eec14dff26491c48b6fb 153 Gene3D G3DSA:3.30.70.920 59 148 9.1E-22 T 31-10-2018 TK1210 49b08b864ae4eec14dff26491c48b6fb 153 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 7 23 5.3E-17 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TK1210 49b08b864ae4eec14dff26491c48b6fb 153 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 23 34 5.3E-17 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TK1210 49b08b864ae4eec14dff26491c48b6fb 153 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 34 53 5.3E-17 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TK1403 c259ed54cb18745abd02e7d72bcd9b40 205 Pfam PF02223 Thymidylate kinase 5 194 1.8E-55 T 31-10-2018 IPR039430 Thymidylate kinase-like domain KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210 TK1403 c259ed54cb18745abd02e7d72bcd9b40 205 Gene3D G3DSA:3.40.50.300 1 203 6.6E-70 T 31-10-2018 TK1403 c259ed54cb18745abd02e7d72bcd9b40 205 Hamap MF_00165 Thymidylate kinase [tmk]. 1 202 29.003 T 31-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 TK1403 c259ed54cb18745abd02e7d72bcd9b40 205 SUPERFAMILY SSF52540 1 202 9.42E-54 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK1403 c259ed54cb18745abd02e7d72bcd9b40 205 ProSitePatterns PS01331 Thymidylate kinase signature. 96 108 - T 31-10-2018 IPR018095 Thymidylate kinase, conserved site GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 TK1403 c259ed54cb18745abd02e7d72bcd9b40 205 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 1 194 7.1E-58 T 31-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 TK0517 df42514f98bf46593b9cb3dda1ad9d45 403 SUPERFAMILY SSF102645 179 402 3.27E-66 T 31-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 TK0517 df42514f98bf46593b9cb3dda1ad9d45 403 SUPERFAMILY SSF52507 18 217 1.96E-47 T 31-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 TK0517 df42514f98bf46593b9cb3dda1ad9d45 403 Pfam PF02441 Flavoprotein 19 188 4.4E-42 T 31-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 TK0517 df42514f98bf46593b9cb3dda1ad9d45 403 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 18 399 1.6E-128 T 31-10-2018 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5|MetaCyc: PWY-7851 TK0517 df42514f98bf46593b9cb3dda1ad9d45 403 Gene3D G3DSA:3.40.50.1950 15 186 2.3E-48 T 31-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 TK0517 df42514f98bf46593b9cb3dda1ad9d45 403 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 193 375 5.7E-57 T 31-10-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 TK0517 df42514f98bf46593b9cb3dda1ad9d45 403 Gene3D G3DSA:3.40.50.10300 187 403 3.5E-71 T 31-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 TK0251 84f6438512f5376f2d2087db801ed520 242 SUPERFAMILY SSF56784 3 202 2.76E-12 T 31-10-2018 IPR036412 HAD-like superfamily TK1444 2e3b225d50d18a71449d08e0c597677d 292 Pfam PF00288 GHMP kinases N terminal domain 74 138 2.3E-11 T 31-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 TK1444 2e3b225d50d18a71449d08e0c597677d 292 TIGRFAM TIGR00191 thrB: homoserine kinase 1 269 4.7E-57 T 31-10-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 TK1444 2e3b225d50d18a71449d08e0c597677d 292 PRINTS PR00958 Homoserine kinase signature 87 102 4.1E-28 T 31-10-2018 TK1444 2e3b225d50d18a71449d08e0c597677d 292 PRINTS PR00958 Homoserine kinase signature 126 139 4.1E-28 T 31-10-2018 TK1444 2e3b225d50d18a71449d08e0c597677d 292 PRINTS PR00958 Homoserine kinase signature 241 256 4.1E-28 T 31-10-2018 TK1444 2e3b225d50d18a71449d08e0c597677d 292 PRINTS PR00958 Homoserine kinase signature 8 23 4.1E-28 T 31-10-2018 TK1444 2e3b225d50d18a71449d08e0c597677d 292 PRINTS PR00958 Homoserine kinase signature 162 179 4.1E-28 T 31-10-2018 TK1444 2e3b225d50d18a71449d08e0c597677d 292 Gene3D G3DSA:3.30.230.10 1 154 4.7E-35 T 31-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TK1444 2e3b225d50d18a71449d08e0c597677d 292 SUPERFAMILY SSF54211 1 155 1.44E-24 T 31-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TK1444 2e3b225d50d18a71449d08e0c597677d 292 Gene3D G3DSA:3.30.70.890 155 284 7.8E-35 T 31-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily TK1444 2e3b225d50d18a71449d08e0c597677d 292 Pfam PF08544 GHMP kinases C terminal 197 267 3.1E-12 T 31-10-2018 IPR013750 GHMP kinase, C-terminal domain TK1444 2e3b225d50d18a71449d08e0c597677d 292 Hamap MF_00384 Homoserine kinase [thrB]. 3 290 26.996 T 31-10-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 TK1444 2e3b225d50d18a71449d08e0c597677d 292 PIRSF PIRSF000676 1 291 1.5E-74 T 31-10-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 TK1444 2e3b225d50d18a71449d08e0c597677d 292 SUPERFAMILY SSF55060 158 287 2.59E-30 T 31-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily TK0071 1698548f2c61016044b4bf005879662f 278 Pfam PF02475 Met-10+ like-protein 29 223 2.8E-68 T 31-10-2018 IPR030382 SAM-dependent methyltransferase TRM5/TYW2-type Reactome: R-HSA-6782861 TK0071 1698548f2c61016044b4bf005879662f 278 SUPERFAMILY SSF53335 19 276 3.16E-68 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TK0071 1698548f2c61016044b4bf005879662f 278 Hamap MF_01922 tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase [taw2]. 26 276 41.369 T 31-10-2018 IPR030867 tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase GO:0006400|GO:0016765 MetaCyc: PWY-7286 TK0071 1698548f2c61016044b4bf005879662f 278 Gene3D G3DSA:3.30.300.110 19 86 6.3E-30 T 31-10-2018 TK0071 1698548f2c61016044b4bf005879662f 278 Gene3D G3DSA:3.40.50.150 87 278 4.3E-55 T 31-10-2018 TK0764 9f60ea7918fab619cc1316bf4b1f280f 1390 SMART SM00487 31 257 6.5E-34 T 31-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TK0764 9f60ea7918fab619cc1316bf4b1f280f 1390 Pfam PF08494 DEAD/H associated 1165 1353 4.6E-54 T 31-10-2018 IPR013701 DEAD/H associated GO:0005524|GO:0016818 TK0764 9f60ea7918fab619cc1316bf4b1f280f 1390 SUPERFAMILY SSF52540 265 937 2.21E-18 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK0764 9f60ea7918fab619cc1316bf4b1f280f 1390 SUPERFAMILY SSF52540 20 229 1.86E-39 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK0764 9f60ea7918fab619cc1316bf4b1f280f 1390 SMART SM00306 344 441 1.6E-14 T 31-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TK0764 9f60ea7918fab619cc1316bf4b1f280f 1390 Pfam PF14890 Intein splicing domain 388 868 2.2E-17 T 31-10-2018 TK0764 9f60ea7918fab619cc1316bf4b1f280f 1390 Gene3D G3DSA:3.40.50.300 870 934 1.7E-7 T 31-10-2018 TK0764 9f60ea7918fab619cc1316bf4b1f280f 1390 SMART SM00490 814 911 0.0072 T 31-10-2018 IPR001650 Helicase, C-terminal TK0764 9f60ea7918fab619cc1316bf4b1f280f 1390 SUPERFAMILY SSF51294 346 870 1.52E-29 T 31-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TK0764 9f60ea7918fab619cc1316bf4b1f280f 1390 Gene3D G3DSA:3.10.28.10 523 736 1.1E-29 T 31-10-2018 IPR027434 Homing endonuclease TK0764 9f60ea7918fab619cc1316bf4b1f280f 1390 Gene3D G3DSA:2.170.16.10 788 869 2.3E-5 T 31-10-2018 TK0764 9f60ea7918fab619cc1316bf4b1f280f 1390 Pfam PF00270 DEAD/DEAH box helicase 36 220 7.9E-27 T 31-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 TK0764 9f60ea7918fab619cc1316bf4b1f280f 1390 PRINTS PR00379 Intein signature 644 656 1.2E-12 T 31-10-2018 IPR006142 Intein GO:0016539 TK0764 9f60ea7918fab619cc1316bf4b1f280f 1390 PRINTS PR00379 Intein signature 548 560 1.2E-12 T 31-10-2018 IPR006142 Intein GO:0016539 TK0764 9f60ea7918fab619cc1316bf4b1f280f 1390 PRINTS PR00379 Intein signature 675 690 1.2E-12 T 31-10-2018 IPR006142 Intein GO:0016539 TK0764 9f60ea7918fab619cc1316bf4b1f280f 1390 PRINTS PR00379 Intein signature 930 939 1.2E-12 T 31-10-2018 IPR006142 Intein GO:0016539 TK0764 9f60ea7918fab619cc1316bf4b1f280f 1390 PRINTS PR00379 Intein signature 403 416 1.2E-12 T 31-10-2018 IPR006142 Intein GO:0016539 TK0764 9f60ea7918fab619cc1316bf4b1f280f 1390 Gene3D G3DSA:3.40.50.300 14 235 8.1E-53 T 31-10-2018 TK0764 9f60ea7918fab619cc1316bf4b1f280f 1390 SMART SM00305 831 876 4.0E-5 T 31-10-2018 IPR003586 Hint domain C-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TK0764 9f60ea7918fab619cc1316bf4b1f280f 1390 SUPERFAMILY SSF55608 631 734 5.83E-18 T 31-10-2018 IPR027434 Homing endonuclease TK0764 9f60ea7918fab619cc1316bf4b1f280f 1390 Pfam PF00271 Helicase conserved C-terminal domain 871 907 9.3E-5 T 31-10-2018 IPR001650 Helicase, C-terminal TK0764 9f60ea7918fab619cc1316bf4b1f280f 1390 Gene3D G3DSA:3.40.50.300 259 348 8.3E-10 T 31-10-2018 TK0764 9f60ea7918fab619cc1316bf4b1f280f 1390 TIGRFAM TIGR01445 intein_Nterm: intein N-terminal splicing region 346 416 9.3E-9 T 31-10-2018 IPR006141 Intein N-terminal splicing region GO:0016539 Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TK0764 9f60ea7918fab619cc1316bf4b1f280f 1390 Pfam PF14528 LAGLIDADG-like domain 643 731 2.4E-13 T 31-10-2018 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 TK0764 9f60ea7918fab619cc1316bf4b1f280f 1390 Gene3D G3DSA:2.170.16.10 349 460 5.5E-10 T 31-10-2018 TK2122 0a3bd33fbc0bbc9dc6efbfef629970e7 383 Pfam PF01472 PUA domain 90 159 2.3E-17 T 31-10-2018 IPR002478 PUA domain GO:0003723 TK2122 0a3bd33fbc0bbc9dc6efbfef629970e7 383 SMART SM00359 90 164 1.2E-22 T 31-10-2018 IPR002478 PUA domain GO:0003723 TK2122 0a3bd33fbc0bbc9dc6efbfef629970e7 383 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 269 281 2.6E-26 T 31-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TK2122 0a3bd33fbc0bbc9dc6efbfef629970e7 383 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 316 332 2.6E-26 T 31-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TK2122 0a3bd33fbc0bbc9dc6efbfef629970e7 383 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 203 213 2.6E-26 T 31-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TK2122 0a3bd33fbc0bbc9dc6efbfef629970e7 383 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 174 188 2.6E-26 T 31-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TK2122 0a3bd33fbc0bbc9dc6efbfef629970e7 383 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 365 382 2.6E-26 T 31-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TK2122 0a3bd33fbc0bbc9dc6efbfef629970e7 383 Gene3D G3DSA:3.30.70.3130 2 80 1.2E-12 T 31-10-2018 TK2122 0a3bd33fbc0bbc9dc6efbfef629970e7 383 SUPERFAMILY SSF88697 89 160 4.03E-18 T 31-10-2018 IPR015947 PUA-like superfamily TK2122 0a3bd33fbc0bbc9dc6efbfef629970e7 383 TIGRFAM TIGR00446 nop2p: NOL1/NOP2/sun family putative RNA methylase 168 382 7.0E-64 T 31-10-2018 IPR011023 Nop2p GO:0003723|GO:0006364|GO:0008757 Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 TK2122 0a3bd33fbc0bbc9dc6efbfef629970e7 383 Gene3D G3DSA:3.40.50.150 189 383 1.4E-62 T 31-10-2018 TK2122 0a3bd33fbc0bbc9dc6efbfef629970e7 383 SUPERFAMILY SSF53335 7 383 2.52E-57 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TK2122 0a3bd33fbc0bbc9dc6efbfef629970e7 383 Pfam PF17125 N-terminal domain of 16S rRNA methyltransferase RsmF 8 86 1.4E-7 T 31-10-2018 IPR031341 Ribosomal RNA small subunit methyltransferase F, N-terminal Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 TK2122 0a3bd33fbc0bbc9dc6efbfef629970e7 383 Pfam PF01189 16S rRNA methyltransferase RsmB/F 193 381 1.4E-57 T 31-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 TK2122 0a3bd33fbc0bbc9dc6efbfef629970e7 383 Gene3D G3DSA:2.30.130.70 81 163 2.3E-18 T 31-10-2018 TK2122 0a3bd33fbc0bbc9dc6efbfef629970e7 383 TIGRFAM TIGR00451 unchar_dom_2: uncharacterized domain 2 91 159 5.9E-7 T 31-10-2018 IPR004521 Uncharacterised domain CHP00451 GO:0003723 TK1014 f04a8eb034464d303fc230dd6efd8a1a 149 SMART SM00670 1 141 6.2E-11 T 31-10-2018 IPR002716 PIN domain TK1014 f04a8eb034464d303fc230dd6efd8a1a 149 Gene3D G3DSA:3.40.50.1010 1 149 8.5E-12 T 31-10-2018 TK1014 f04a8eb034464d303fc230dd6efd8a1a 149 SUPERFAMILY SSF88723 1 147 1.57E-18 T 31-10-2018 IPR029060 PIN-like domain superfamily TK1014 f04a8eb034464d303fc230dd6efd8a1a 149 Pfam PF01850 PIN domain 3 144 4.3E-22 T 31-10-2018 IPR002716 PIN domain TK2097 b6914c08763e28ae4c5cb19fd324b0c0 160 Gene3D G3DSA:3.30.2130.30 1 151 1.1E-19 T 31-10-2018 TK2097 b6914c08763e28ae4c5cb19fd324b0c0 160 SMART SM00981 62 149 4.8E-19 T 31-10-2018 IPR004114 THUMP domain GO:0003723 TK2097 b6914c08763e28ae4c5cb19fd324b0c0 160 SUPERFAMILY SSF143437 34 148 8.37E-18 T 31-10-2018 TK2097 b6914c08763e28ae4c5cb19fd324b0c0 160 Pfam PF02926 THUMP domain 30 148 9.5E-25 T 31-10-2018 IPR004114 THUMP domain GO:0003723 TK0960 4b6d74776152689574d9a01ac095b457 272 SUPERFAMILY SSF52402 21 205 1.41E-29 T 31-10-2018 TK0960 4b6d74776152689574d9a01ac095b457 272 Gene3D G3DSA:3.40.50.620 19 191 9.6E-29 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TK0960 4b6d74776152689574d9a01ac095b457 272 Pfam PF06508 Queuosine biosynthesis protein QueC 23 82 1.3E-7 T 31-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 TK0960 4b6d74776152689574d9a01ac095b457 272 PIRSF PIRSF036670 1 261 2.2E-124 T 31-10-2018 IPR012122 ATPase, PP-loop, MJ1016-related TK2292 3c1838996795b6b2b4d4bb59eebf184a 67 Pfam PF00833 Ribosomal S17 1 64 2.1E-15 T 31-10-2018 IPR001210 Ribosomal protein S17e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK2292 3c1838996795b6b2b4d4bb59eebf184a 67 Gene3D G3DSA:1.10.60.20 1 62 4.2E-29 T 31-10-2018 IPR036401 Ribosomal protein S17e-like superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK2292 3c1838996795b6b2b4d4bb59eebf184a 67 SUPERFAMILY SSF116820 1 60 1.09E-23 T 31-10-2018 IPR036401 Ribosomal protein S17e-like superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK2292 3c1838996795b6b2b4d4bb59eebf184a 67 ProSitePatterns PS00712 Ribosomal protein S17e signature. 41 56 - T 31-10-2018 IPR018273 Ribosomal protein S17e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK2292 3c1838996795b6b2b4d4bb59eebf184a 67 Hamap MF_00511 30S ribosomal protein S17e [rps17e]. 1 63 22.421 T 31-10-2018 IPR001210 Ribosomal protein S17e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK0001 82e3e90addd1e7eccddf59f47c5f982b 1671 SUPERFAMILY SSF56672 739 853 2.61E-25 T 31-10-2018 TK0001 82e3e90addd1e7eccddf59f47c5f982b 1671 SMART SM00486 133 1447 2.8E-82 T 31-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TK0001 82e3e90addd1e7eccddf59f47c5f982b 1671 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 745 767 3.7E-7 T 31-10-2018 IPR030934 Intein C-terminal splicing region TK0001 82e3e90addd1e7eccddf59f47c5f982b 1671 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 1365 1389 3.2E-7 T 31-10-2018 IPR030934 Intein C-terminal splicing region TK0001 82e3e90addd1e7eccddf59f47c5f982b 1671 Pfam PF14528 LAGLIDADG-like domain 1225 1283 9.3E-6 T 31-10-2018 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 TK0001 82e3e90addd1e7eccddf59f47c5f982b 1671 Pfam PF14528 LAGLIDADG-like domain 623 701 1.4E-7 T 31-10-2018 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 TK0001 82e3e90addd1e7eccddf59f47c5f982b 1671 SUPERFAMILY SSF55608 1208 1300 7.18E-19 T 31-10-2018 IPR027434 Homing endonuclease TK0001 82e3e90addd1e7eccddf59f47c5f982b 1671 SUPERFAMILY SSF51294 852 1389 4.12E-43 T 31-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TK0001 82e3e90addd1e7eccddf59f47c5f982b 1671 Pfam PF14890 Intein splicing domain 440 766 2.1E-9 T 31-10-2018 TK0001 82e3e90addd1e7eccddf59f47c5f982b 1671 SUPERFAMILY SSF56672 349 406 2.17E-11 T 31-10-2018 TK0001 82e3e90addd1e7eccddf59f47c5f982b 1671 SUPERFAMILY SSF56672 1387 1657 3.11E-83 T 31-10-2018 TK0001 82e3e90addd1e7eccddf59f47c5f982b 1671 Pfam PF00136 DNA polymerase family B 1388 1643 2.0E-46 T 31-10-2018 IPR006134 DNA-directed DNA polymerase, family B, multifunctional domain GO:0000166|GO:0003677 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TK0001 82e3e90addd1e7eccddf59f47c5f982b 1671 Pfam PF00136 DNA polymerase family B 762 853 2.0E-19 T 31-10-2018 IPR006134 DNA-directed DNA polymerase, family B, multifunctional domain GO:0000166|GO:0003677 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TK0001 82e3e90addd1e7eccddf59f47c5f982b 1671 Pfam PF03104 DNA polymerase family B, exonuclease domain 22 129 4.4E-14 T 31-10-2018 IPR006133 DNA-directed DNA polymerase, family B, exonuclease domain KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TK0001 82e3e90addd1e7eccddf59f47c5f982b 1671 Pfam PF03104 DNA polymerase family B, exonuclease domain 130 278 3.4E-33 T 31-10-2018 IPR006133 DNA-directed DNA polymerase, family B, exonuclease domain KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TK0001 82e3e90addd1e7eccddf59f47c5f982b 1671 Gene3D G3DSA:3.30.420.10 131 347 4.3E-174 T 31-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 TK0001 82e3e90addd1e7eccddf59f47c5f982b 1671 Gene3D G3DSA:3.30.342.10 3 366 4.3E-174 T 31-10-2018 TK0001 82e3e90addd1e7eccddf59f47c5f982b 1671 TIGRFAM TIGR01445 intein_Nterm: intein N-terminal splicing region 862 950 3.9E-10 T 31-10-2018 IPR006141 Intein N-terminal splicing region GO:0016539 Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TK0001 82e3e90addd1e7eccddf59f47c5f982b 1671 Gene3D G3DSA:1.10.10.1010 979 1124 1.4E-265 T 31-10-2018 TK0001 82e3e90addd1e7eccddf59f47c5f982b 1671 Gene3D G3DSA:3.10.28.10 1125 1293 1.4E-265 T 31-10-2018 IPR027434 Homing endonuclease TK0001 82e3e90addd1e7eccddf59f47c5f982b 1671 Gene3D G3DSA:3.10.28.10 521 695 3.3E-11 T 31-10-2018 IPR027434 Homing endonuclease TK0001 82e3e90addd1e7eccddf59f47c5f982b 1671 PRINTS PR00379 Intein signature 938 951 1.1E-23 T 31-10-2018 IPR006142 Intein GO:0016539 TK0001 82e3e90addd1e7eccddf59f47c5f982b 1671 PRINTS PR00379 Intein signature 1363 1380 1.1E-23 T 31-10-2018 IPR006142 Intein GO:0016539 TK0001 82e3e90addd1e7eccddf59f47c5f982b 1671 PRINTS PR00379 Intein signature 1225 1237 1.1E-23 T 31-10-2018 IPR006142 Intein GO:0016539 TK0001 82e3e90addd1e7eccddf59f47c5f982b 1671 PRINTS PR00379 Intein signature 1129 1141 1.1E-23 T 31-10-2018 IPR006142 Intein GO:0016539 TK0001 82e3e90addd1e7eccddf59f47c5f982b 1671 PRINTS PR00379 Intein signature 1252 1267 1.1E-23 T 31-10-2018 IPR006142 Intein GO:0016539 TK0001 82e3e90addd1e7eccddf59f47c5f982b 1671 Gene3D G3DSA:1.10.132.60 1504 1670 8.6E-63 T 31-10-2018 TK0001 82e3e90addd1e7eccddf59f47c5f982b 1671 SUPERFAMILY SSF53098 1 347 3.8E-90 T 31-10-2018 IPR012337 Ribonuclease H-like superfamily TK0001 82e3e90addd1e7eccddf59f47c5f982b 1671 TIGRFAM TIGR00592 pol2: DNA polymerase (pol2) 1387 1642 2.2E-101 T 31-10-2018 TK0001 82e3e90addd1e7eccddf59f47c5f982b 1671 TIGRFAM TIGR00592 pol2: DNA polymerase (pol2) 2 408 1.3E-80 T 31-10-2018 TK0001 82e3e90addd1e7eccddf59f47c5f982b 1671 Gene3D G3DSA:3.90.1600.10 740 854 6.6E-20 T 31-10-2018 IPR023211 DNA polymerase, palm domain superfamily KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TK0001 82e3e90addd1e7eccddf59f47c5f982b 1671 Gene3D G3DSA:3.90.1600.10 1387 1503 2.5E-39 T 31-10-2018 IPR023211 DNA polymerase, palm domain superfamily KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TK0001 82e3e90addd1e7eccddf59f47c5f982b 1671 SUPERFAMILY SSF55608 610 721 1.08E-16 T 31-10-2018 IPR027434 Homing endonuclease TK0001 82e3e90addd1e7eccddf59f47c5f982b 1671 ProSitePatterns PS00116 DNA polymerase family B signature. 1435 1443 - T 31-10-2018 IPR017964 DNA-directed DNA polymerase, family B, conserved site GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TK0001 82e3e90addd1e7eccddf59f47c5f982b 1671 Gene3D G3DSA:3.30.1490.210 1294 1346 1.4E-265 T 31-10-2018 TK0001 82e3e90addd1e7eccddf59f47c5f982b 1671 Gene3D G3DSA:2.170.16.10 865 1386 1.4E-265 T 31-10-2018 TK0001 82e3e90addd1e7eccddf59f47c5f982b 1671 Pfam PF14890 Intein splicing domain 861 1388 2.3E-66 T 31-10-2018 TK0001 82e3e90addd1e7eccddf59f47c5f982b 1671 SUPERFAMILY SSF51294 406 765 7.72E-21 T 31-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TK0001 82e3e90addd1e7eccddf59f47c5f982b 1671 Gene3D G3DSA:3.90.1600.10 369 408 2.9E-9 T 31-10-2018 IPR023211 DNA polymerase, palm domain superfamily KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TK0001 82e3e90addd1e7eccddf59f47c5f982b 1671 SMART SM00306 405 495 5.0E-13 T 31-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TK0001 82e3e90addd1e7eccddf59f47c5f982b 1671 SMART SM00306 850 975 2.9E-26 T 31-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TK0001 82e3e90addd1e7eccddf59f47c5f982b 1671 SMART SM00305 1346 1394 2.5E-12 T 31-10-2018 IPR003586 Hint domain C-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TK0001 82e3e90addd1e7eccddf59f47c5f982b 1671 SMART SM00305 726 772 1.9E-10 T 31-10-2018 IPR003586 Hint domain C-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TK1015 6b3f4eed41318c9b5eff4d2af7617581 925 Pfam PF00271 Helicase conserved C-terminal domain 238 336 1.8E-18 T 31-10-2018 IPR001650 Helicase, C-terminal TK1015 6b3f4eed41318c9b5eff4d2af7617581 925 SMART SM00490 259 341 2.2E-23 T 31-10-2018 IPR001650 Helicase, C-terminal TK1015 6b3f4eed41318c9b5eff4d2af7617581 925 Gene3D G3DSA:3.40.50.300 3 202 3.7E-46 T 31-10-2018 TK1015 6b3f4eed41318c9b5eff4d2af7617581 925 Pfam PF08494 DEAD/H associated 583 750 1.2E-16 T 31-10-2018 IPR013701 DEAD/H associated GO:0005524|GO:0016818 TK1015 6b3f4eed41318c9b5eff4d2af7617581 925 SUPERFAMILY SSF52540 28 350 1.4E-51 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK1015 6b3f4eed41318c9b5eff4d2af7617581 925 Pfam PF00270 DEAD/DEAH box helicase 18 182 1.7E-27 T 31-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 TK1015 6b3f4eed41318c9b5eff4d2af7617581 925 SMART SM00487 12 210 7.6E-35 T 31-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TK1015 6b3f4eed41318c9b5eff4d2af7617581 925 Gene3D G3DSA:3.40.50.300 203 371 1.8E-30 T 31-10-2018 TK1015 6b3f4eed41318c9b5eff4d2af7617581 925 PIRSF PIRSF037307 1 912 0.0 T 31-10-2018 IPR017170 Lhr-like ATP-dependent RNA helicase, predicted GO:0005524|GO:0016818 TK1069 d2d4ae0ba61193811ce9b1fdebaba187 114 SUPERFAMILY SSF50118 4 110 4.8E-13 T 31-10-2018 TK1069 d2d4ae0ba61193811ce9b1fdebaba187 114 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 5 107 1.7E-12 T 31-10-2018 IPR003477 mRNA interferase PemK-like GO:0003677 TK1069 d2d4ae0ba61193811ce9b1fdebaba187 114 Gene3D G3DSA:2.30.30.110 13 112 4.8E-12 T 31-10-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor TK1828 a337e6c279815f36cb8ebe3bf6c1cea8 326 Pfam PF01087 Galactose-1-phosphate uridyl transferase, N-terminal domain 2 151 1.8E-24 T 31-10-2018 IPR005849 Galactose-1-phosphate uridyl transferase, N-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 TK1828 a337e6c279815f36cb8ebe3bf6c1cea8 326 TIGRFAM TIGR00209 galT_1: galactose-1-phosphate uridylyltransferase 48 310 2.1E-49 T 31-10-2018 IPR001937 Galactose-1-phosphate uridyl transferase, class I GO:0008108|GO:0008270|GO:0033499 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 TK1828 a337e6c279815f36cb8ebe3bf6c1cea8 326 Gene3D G3DSA:3.30.428.10 31 150 4.1E-92 T 31-10-2018 IPR036265 HIT-like superfamily TK1828 a337e6c279815f36cb8ebe3bf6c1cea8 326 Gene3D G3DSA:3.30.428.10 3 309 4.1E-92 T 31-10-2018 IPR036265 HIT-like superfamily TK1828 a337e6c279815f36cb8ebe3bf6c1cea8 326 Pfam PF02744 Galactose-1-phosphate uridyl transferase, C-terminal domain 162 313 3.0E-19 T 31-10-2018 IPR005850 Galactose-1-phosphate uridyl transferase, C-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 TK1828 a337e6c279815f36cb8ebe3bf6c1cea8 326 SUPERFAMILY SSF54197 1 151 3.83E-46 T 31-10-2018 IPR036265 HIT-like superfamily TK1828 a337e6c279815f36cb8ebe3bf6c1cea8 326 PIRSF PIRSF000808 1 314 6.8E-114 T 31-10-2018 IPR001937 Galactose-1-phosphate uridyl transferase, class I GO:0008108|GO:0008270|GO:0033499 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 TK1828 a337e6c279815f36cb8ebe3bf6c1cea8 326 SUPERFAMILY SSF54197 154 315 5.25E-47 T 31-10-2018 IPR036265 HIT-like superfamily TK1125 68ae5e5ad3bf8d60c1009159d6000885 382 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 22 257 3.0E-80 T 31-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 TK1125 68ae5e5ad3bf8d60c1009159d6000885 382 Gene3D G3DSA:3.40.50.920 273 381 1.0E-24 T 31-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TK1125 68ae5e5ad3bf8d60c1009159d6000885 382 SUPERFAMILY SSF52922 274 378 1.02E-26 T 31-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TK1125 68ae5e5ad3bf8d60c1009159d6000885 382 Gene3D G3DSA:3.40.50.970 1 199 8.9E-84 T 31-10-2018 TK1125 68ae5e5ad3bf8d60c1009159d6000885 382 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 282 376 4.8E-21 T 31-10-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II TK1125 68ae5e5ad3bf8d60c1009159d6000885 382 SUPERFAMILY SSF52518 12 265 4.76E-71 T 31-10-2018 IPR029061 Thiamin diphosphate-binding fold TK0018 2939ad990e01dbcab9091c7e818608dc 247 SUPERFAMILY SSF161098 6 241 1.96E-48 T 31-10-2018 IPR035906 MetI-like superfamily TK0018 2939ad990e01dbcab9091c7e818608dc 247 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 70 242 5.7E-21 T 31-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TK0018 2939ad990e01dbcab9091c7e818608dc 247 Gene3D G3DSA:1.10.3720.10 5 247 2.1E-66 T 31-10-2018 IPR035906 MetI-like superfamily TK0845 fe91ef60862b4d1bb230bee7a6fca269 278 Pfam PF00248 Aldo/keto reductase family 21 272 1.3E-63 T 31-10-2018 IPR023210 NADP-dependent oxidoreductase domain TK0845 fe91ef60862b4d1bb230bee7a6fca269 278 PIRSF PIRSF000097 8 126 1.7E-19 T 31-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 TK0845 fe91ef60862b4d1bb230bee7a6fca269 278 PIRSF PIRSF000097 125 276 3.4E-21 T 31-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 TK0845 fe91ef60862b4d1bb230bee7a6fca269 278 SUPERFAMILY SSF51430 15 272 3.8E-78 T 31-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily TK0845 fe91ef60862b4d1bb230bee7a6fca269 278 Gene3D G3DSA:3.20.20.100 14 275 1.3E-90 T 31-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily TK0845 fe91ef60862b4d1bb230bee7a6fca269 278 PRINTS PR00069 Aldo-keto reductase signature 105 123 1.3E-19 T 31-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 TK0845 fe91ef60862b4d1bb230bee7a6fca269 278 PRINTS PR00069 Aldo-keto reductase signature 212 236 1.3E-19 T 31-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 TK0845 fe91ef60862b4d1bb230bee7a6fca269 278 PRINTS PR00069 Aldo-keto reductase signature 49 73 1.3E-19 T 31-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 TK0845 fe91ef60862b4d1bb230bee7a6fca269 278 PRINTS PR00069 Aldo-keto reductase signature 137 154 1.3E-19 T 31-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 TK0845 fe91ef60862b4d1bb230bee7a6fca269 278 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 137 154 - T 31-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 TK2289 6c07160689f4d88d4ce6513dc6b7af6b 67 SMART SM00803 12 66 0.0032 T 31-10-2018 IPR004823 TATA box binding protein associated factor (TAF) GO:0006352 TK2289 6c07160689f4d88d4ce6513dc6b7af6b 67 SUPERFAMILY SSF47113 3 66 3.47E-19 T 31-10-2018 IPR009072 Histone-fold GO:0046982 TK2289 6c07160689f4d88d4ce6513dc6b7af6b 67 Gene3D G3DSA:1.10.20.10 1 67 1.1E-22 T 31-10-2018 IPR009072 Histone-fold GO:0046982 TK2289 6c07160689f4d88d4ce6513dc6b7af6b 67 Pfam PF00808 Histone-like transcription factor (CBF/NF-Y) and archaeal histone 2 65 5.8E-20 T 31-10-2018 IPR003958 Transcription factor CBF/NF-Y/archaeal histone domain TK1455 96d1501f0bf4098f4dd913bb15538e9c 356 SUPERFAMILY SSF53092 2 105 3.49E-12 T 31-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal TK1455 96d1501f0bf4098f4dd913bb15538e9c 356 Pfam PF00557 Metallopeptidase family M24 139 338 2.9E-70 T 31-10-2018 IPR000994 Peptidase M24 TK1455 96d1501f0bf4098f4dd913bb15538e9c 356 Pfam PF01321 Creatinase/Prolidase N-terminal domain 2 104 4.0E-16 T 31-10-2018 IPR000587 Creatinase, N-terminal GO:0016787 TK1455 96d1501f0bf4098f4dd913bb15538e9c 356 SUPERFAMILY SSF55920 130 356 1.44E-76 T 31-10-2018 IPR036005 Creatinase/aminopeptidase-like TK1455 96d1501f0bf4098f4dd913bb15538e9c 356 Gene3D G3DSA:3.90.230.10 131 356 3.3E-84 T 31-10-2018 TK1455 96d1501f0bf4098f4dd913bb15538e9c 356 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 286 298 - T 31-10-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site TK1455 96d1501f0bf4098f4dd913bb15538e9c 356 Gene3D G3DSA:3.40.350.10 1 129 6.5E-28 T 31-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal TK1477 6de3d6944a2e90b9eefc4890941fd401 291 SUPERFAMILY SSF53213 55 255 1.86E-7 T 31-10-2018 TK1477 6de3d6944a2e90b9eefc4890941fd401 291 Gene3D G3DSA:3.40.830.10 1 290 1.0E-65 T 31-10-2018 TK1477 6de3d6944a2e90b9eefc4890941fd401 291 TIGRFAM TIGR04336 AmmeMemoSam_B: AmmeMemoRadiSam system protein B 3 289 7.3E-88 T 31-10-2018 TK1477 6de3d6944a2e90b9eefc4890941fd401 291 Pfam PF01875 Memo-like protein 5 288 2.1E-72 T 31-10-2018 IPR002737 MEMO1 family Reactome: R-HSA-6785631 TK1477 6de3d6944a2e90b9eefc4890941fd401 291 Hamap MF_00055 MEMO1 family protein . 1 290 60.05 T 31-10-2018 IPR002737 MEMO1 family Reactome: R-HSA-6785631 TK2089 f42b908008188aa88eb3d600fa8a1d7c 176 SUPERFAMILY SSF56770 35 164 2.75E-53 T 31-10-2018 TK2089 f42b908008188aa88eb3d600fa8a1d7c 176 Gene3D G3DSA:3.40.50.12280 10 176 8.3E-53 T 31-10-2018 TK2089 f42b908008188aa88eb3d600fa8a1d7c 176 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 47 156 5.0E-28 T 31-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TK1813 1533ab733180a0089c0d62448beb1678 396 Gene3D G3DSA:1.20.1530.20 1 393 4.0E-75 T 31-10-2018 IPR038770 Sodium/solute symporter superfamily TK1813 1533ab733180a0089c0d62448beb1678 396 Pfam PF00999 Sodium/hydrogen exchanger family 9 383 3.5E-55 T 31-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 TK1893 479058e44d2a5efa3edb4049b86d6db3 248 SUPERFAMILY SSF82544 31 247 1.96E-62 T 31-10-2018 TK1893 479058e44d2a5efa3edb4049b86d6db3 248 Pfam PF05161 MOFRL family 135 240 4.7E-36 T 31-10-2018 IPR007835 MOFRL domain Reactome: R-HSA-70350 TK1893 479058e44d2a5efa3edb4049b86d6db3 248 Gene3D G3DSA:3.40.1480.10 67 248 3.4E-63 T 31-10-2018 IPR037035 Glycerate kinase-like, C-terminal domain superfamily TK1233 b969e782eb44563aff64d26ea95630a2 182 Pfam PF01944 Stage II sporulation protein M 13 177 4.4E-34 T 31-10-2018 IPR002798 Stage II sporulation protein M-like TK1439 e2ed947ab462d4f728e22aa437dd23ea 138 Pfam PF08753 NikR C terminal nickel binding domain 55 131 4.9E-33 T 31-10-2018 IPR014864 Transcription factor, NikR, nickel binding C-terminal TK1439 e2ed947ab462d4f728e22aa437dd23ea 138 Hamap MF_00476 Nickel-responsive regulator [nikR]. 3 133 30.55 T 31-10-2018 IPR022988 Nickel-responsive transcriptional regulator NikR GO:0003677|GO:0006355|GO:0010045|GO:0016151 TK1439 e2ed947ab462d4f728e22aa437dd23ea 138 SUPERFAMILY SSF55021 53 133 1.99E-28 T 31-10-2018 TK1439 e2ed947ab462d4f728e22aa437dd23ea 138 SUPERFAMILY SSF47598 2 48 1.93E-13 T 31-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 TK1439 e2ed947ab462d4f728e22aa437dd23ea 138 Gene3D G3DSA:1.10.1220.10 10 50 4.4E-22 T 31-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 TK1439 e2ed947ab462d4f728e22aa437dd23ea 138 Gene3D G3DSA:3.30.70.1150 51 138 6.0E-37 T 31-10-2018 IPR027271 Acetolactate synthase/Transcription factor NikR, C-terminal TK1439 e2ed947ab462d4f728e22aa437dd23ea 138 Pfam PF01402 Ribbon-helix-helix protein, copG family 5 42 3.8E-8 T 31-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 TK0147 6d382cc9215ea711a13d57de1c715412 288 Hamap MF_00198 Polyamine aminopropyltransferase [speE]. 8 286 36.443 T 31-10-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 TK0147 6d382cc9215ea711a13d57de1c715412 288 SUPERFAMILY SSF53335 9 286 7.44E-75 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TK0147 6d382cc9215ea711a13d57de1c715412 288 Gene3D G3DSA:3.40.50.150 62 287 1.6E-75 T 31-10-2018 TK0147 6d382cc9215ea711a13d57de1c715412 288 Gene3D G3DSA:2.30.140.10 6 60 3.5E-24 T 31-10-2018 IPR037163 Spermidine synthase, tetramerisation domain superfamily KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 TK0147 6d382cc9215ea711a13d57de1c715412 288 ProSitePatterns PS01330 Polyamine biosynthesis (PABS) domain signature. 84 97 - T 31-10-2018 IPR030373 Polyamine biosynthesis domain, conserved site KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 TK0147 6d382cc9215ea711a13d57de1c715412 288 Pfam PF01564 Spermine/spermidine synthase domain 64 247 2.3E-49 T 31-10-2018 TK0147 6d382cc9215ea711a13d57de1c715412 288 TIGRFAM TIGR00417 speE: spermidine synthase 10 280 3.5E-80 T 31-10-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 TK0147 6d382cc9215ea711a13d57de1c715412 288 Pfam PF17284 Spermidine synthase tetramerisation domain 10 60 7.4E-14 T 31-10-2018 IPR035246 Spermidine synthase, tetramerisation domain KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 TK1449 0dcc45d40b6009b178672951a3e64d9e 366 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 6 363 2.1E-106 T 31-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 TK1449 0dcc45d40b6009b178672951a3e64d9e 366 SUPERFAMILY SSF53383 12 363 1.95E-90 T 31-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TK1449 0dcc45d40b6009b178672951a3e64d9e 366 Gene3D G3DSA:3.40.640.10 1 229 1.9E-66 T 31-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TK1449 0dcc45d40b6009b178672951a3e64d9e 366 Gene3D G3DSA:3.90.1150.10 230 365 1.1E-41 T 31-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TK1449 0dcc45d40b6009b178672951a3e64d9e 366 PIRSF PIRSF001434 1 365 2.8E-120 T 31-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 TK1048 19929fd7c636bba76e30aa0e559b302f 232 PRINTS PR01874 DNA repair protein radA signature 15 43 3.0E-9 T 31-10-2018 TK1048 19929fd7c636bba76e30aa0e559b302f 232 PRINTS PR01874 DNA repair protein radA signature 57 74 3.0E-9 T 31-10-2018 TK1048 19929fd7c636bba76e30aa0e559b302f 232 Pfam PF06745 KaiC 6 229 1.6E-51 T 31-10-2018 IPR014774 KaiC-like domain TK1048 19929fd7c636bba76e30aa0e559b302f 232 Gene3D G3DSA:3.40.50.300 4 231 1.5E-57 T 31-10-2018 TK1048 19929fd7c636bba76e30aa0e559b302f 232 SUPERFAMILY SSF52540 5 230 3.43E-41 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK1594 e983fad0e38653c61b4fd40890c39247 506 SUPERFAMILY SSF82866 299 491 1.7E-27 T 31-10-2018 TK1594 e983fad0e38653c61b4fd40890c39247 506 Pfam PF02355 Protein export membrane protein 328 489 1.9E-19 T 31-10-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial TK1594 e983fad0e38653c61b4fd40890c39247 506 Gene3D G3DSA:1.20.1640.10 313 498 7.0E-14 T 31-10-2018 TK1594 e983fad0e38653c61b4fd40890c39247 506 Gene3D G3DSA:3.30.70.3400 35 120 1.4E-8 T 31-10-2018 TK1594 e983fad0e38653c61b4fd40890c39247 506 Hamap MF_01463_A Protein translocase subunit SecD [secD]. 6 505 18.998 T 31-10-2018 IPR024912 Protein translocase subunit SecD, archaeal TK1886 9a3ba2bf2eb39c512442a702fb9bb7ca 480 SUPERFAMILY SSF64153 4 225 8.63E-48 T 31-10-2018 IPR036652 YjeF N-terminal domain superfamily MetaCyc: PWY-6938 TK1886 9a3ba2bf2eb39c512442a702fb9bb7ca 480 Hamap MF_01966 NAD(P)H-hydrate epimerase [nnrE]. 1 198 18.503 T 31-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 TK1886 9a3ba2bf2eb39c512442a702fb9bb7ca 480 TIGRFAM TIGR00197 yjeF_nterm: YjeF family N-terminal domain 8 183 1.2E-41 T 31-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 TK1886 9a3ba2bf2eb39c512442a702fb9bb7ca 480 Pfam PF03853 YjeF-related protein N-terminus 22 182 1.0E-32 T 31-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 TK1886 9a3ba2bf2eb39c512442a702fb9bb7ca 480 Gene3D G3DSA:3.40.50.10260 9 203 4.4E-42 T 31-10-2018 IPR036652 YjeF N-terminal domain superfamily MetaCyc: PWY-6938 TK1886 9a3ba2bf2eb39c512442a702fb9bb7ca 480 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 204 479 21.846 T 31-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 TK1886 9a3ba2bf2eb39c512442a702fb9bb7ca 480 Gene3D G3DSA:3.40.1190.20 210 477 3.6E-77 T 31-10-2018 IPR029056 Ribokinase-like TK1886 9a3ba2bf2eb39c512442a702fb9bb7ca 480 PIRSF PIRSF017184 2 479 7.5E-97 T 31-10-2018 IPR030677 Bifunctional NAD(P)H-hydrate repair enzyme Nnr GO:0052855 MetaCyc: PWY-6938 TK1886 9a3ba2bf2eb39c512442a702fb9bb7ca 480 ProSitePatterns PS01050 YjeF C-terminal domain signature 2. 415 425 - T 31-10-2018 IPR017953 Carbohydrate kinase, predicted, conserved site TK1886 9a3ba2bf2eb39c512442a702fb9bb7ca 480 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 211 475 4.7E-72 T 31-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 TK1886 9a3ba2bf2eb39c512442a702fb9bb7ca 480 SUPERFAMILY SSF53613 212 475 3.45E-62 T 31-10-2018 IPR029056 Ribokinase-like TK1886 9a3ba2bf2eb39c512442a702fb9bb7ca 480 Pfam PF01256 Carbohydrate kinase 227 471 4.3E-51 T 31-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 TK0629 0dd2f66e2826348db930d4dedff9fc6b 145 SUPERFAMILY SSF50341 2 143 1.7E-38 T 31-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 TK0629 0dd2f66e2826348db930d4dedff9fc6b 145 Gene3D G3DSA:2.30.30.40 7 135 1.7E-42 T 31-10-2018 TK0629 0dd2f66e2826348db930d4dedff9fc6b 145 SMART SM00260 1 141 5.1E-49 T 31-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 TK0629 0dd2f66e2826348db930d4dedff9fc6b 145 Gene3D G3DSA:2.40.50.180 24 136 1.7E-42 T 31-10-2018 TK0629 0dd2f66e2826348db930d4dedff9fc6b 145 Pfam PF01584 CheW-like domain 5 143 1.4E-36 T 31-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 TK0238 546fef713b4ef5f6f48080031e3123fe 223 SUPERFAMILY SSF56317 1 217 2.88E-39 T 31-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily TK0238 546fef713b4ef5f6f48080031e3123fe 223 Pfam PF00795 Carbon-nitrogen hydrolase 2 167 2.7E-17 T 31-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 TK0238 546fef713b4ef5f6f48080031e3123fe 223 Gene3D G3DSA:3.60.110.10 1 220 9.8E-33 T 31-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily TK1408 3350441e3eaa690f673b30a9fcc05955 573 Pfam PF03950 tRNA synthetases class I (E and Q), anti-codon binding domain 410 559 8.4E-30 T 31-10-2018 IPR020059 Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 TK1408 3350441e3eaa690f673b30a9fcc05955 573 SUPERFAMILY SSF50715 410 570 1.99E-31 T 31-10-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 TK1408 3350441e3eaa690f673b30a9fcc05955 573 Gene3D G3DSA:3.40.50.620 67 411 1.6E-119 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TK1408 3350441e3eaa690f673b30a9fcc05955 573 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 100 407 1.4E-84 T 31-10-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0004812|GO:0005524|GO:0043039 TK1408 3350441e3eaa690f673b30a9fcc05955 573 Gene3D G3DSA:2.40.240.10 419 517 7.1E-43 T 31-10-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, N-terminal Reactome: R-HSA-2408517|Reactome: R-HSA-379716 TK1408 3350441e3eaa690f673b30a9fcc05955 573 TIGRFAM TIGR00463 gltX_arch: glutamate--tRNA ligase 5 573 5.1E-216 T 31-10-2018 IPR004526 Glutamyl-tRNA synthetase, archaeal/eukaryotic cytosolic GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 TK1408 3350441e3eaa690f673b30a9fcc05955 573 Gene3D G3DSA:2.40.240.100 412 572 7.1E-43 T 31-10-2018 TK1408 3350441e3eaa690f673b30a9fcc05955 573 PRINTS PR00987 Glutamyl-tRNA synthetase signature 118 129 3.7E-21 T 31-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 TK1408 3350441e3eaa690f673b30a9fcc05955 573 PRINTS PR00987 Glutamyl-tRNA synthetase signature 104 116 3.7E-21 T 31-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 TK1408 3350441e3eaa690f673b30a9fcc05955 573 PRINTS PR00987 Glutamyl-tRNA synthetase signature 133 146 3.7E-21 T 31-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 TK1408 3350441e3eaa690f673b30a9fcc05955 573 PRINTS PR00987 Glutamyl-tRNA synthetase signature 281 291 3.7E-21 T 31-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 TK1408 3350441e3eaa690f673b30a9fcc05955 573 PRINTS PR00987 Glutamyl-tRNA synthetase signature 297 305 3.7E-21 T 31-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 TK1408 3350441e3eaa690f673b30a9fcc05955 573 SUPERFAMILY SSF52374 100 416 8.85E-91 T 31-10-2018 TK1408 3350441e3eaa690f673b30a9fcc05955 573 Hamap MF_02076 Glutamate--tRNA ligase [gltX]. 8 571 40.266 T 31-10-2018 IPR004526 Glutamyl-tRNA synthetase, archaeal/eukaryotic cytosolic GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 TK1770 8ee6a0a50b97782599f99845c0dd0a0b 656 Gene3D G3DSA:3.20.20.80 200 581 7.7E-141 T 31-10-2018 TK1770 8ee6a0a50b97782599f99845c0dd0a0b 656 Pfam PF02903 Alpha amylase, N-terminal ig-like domain 110 210 7.4E-14 T 31-10-2018 IPR004185 Glycoside hydrolase, family 13, N-terminal Ig-like domain GO:0004553|GO:0005975 TK1770 8ee6a0a50b97782599f99845c0dd0a0b 656 Pfam PF00128 Alpha amylase, catalytic domain 236 542 1.5E-59 T 31-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 TK1770 8ee6a0a50b97782599f99845c0dd0a0b 656 Gene3D G3DSA:2.60.40.10 1 105 2.2E-16 T 31-10-2018 IPR013783 Immunoglobulin-like fold TK1770 8ee6a0a50b97782599f99845c0dd0a0b 656 SUPERFAMILY SSF51011 584 633 3.1E-5 T 31-10-2018 TK1770 8ee6a0a50b97782599f99845c0dd0a0b 656 SUPERFAMILY SSF81296 26 84 4.62E-9 T 31-10-2018 IPR014756 Immunoglobulin E-set TK1770 8ee6a0a50b97782599f99845c0dd0a0b 656 Gene3D G3DSA:2.60.40.10 106 199 1.7E-26 T 31-10-2018 IPR013783 Immunoglobulin-like fold TK1770 8ee6a0a50b97782599f99845c0dd0a0b 656 SMART SM00642 212 575 7.9E-94 T 31-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 TK1770 8ee6a0a50b97782599f99845c0dd0a0b 656 SUPERFAMILY SSF81296 108 215 1.9E-14 T 31-10-2018 IPR014756 Immunoglobulin E-set TK1770 8ee6a0a50b97782599f99845c0dd0a0b 656 SUPERFAMILY SSF51445 196 584 6.53E-95 T 31-10-2018 IPR017853 Glycoside hydrolase superfamily TK0305 833820bbbf470c1814d0057b25e9c8fd 225 PIRSF PIRSF005650 1 225 2.7E-61 T 31-10-2018 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 TK0305 833820bbbf470c1814d0057b25e9c8fd 225 Hamap MF_01220_A Uridylate kinase [pyrH]. 1 225 35.335 T 31-10-2018 IPR011818 Uridylate kinase, archaeal/spirochete, putative GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 TK0305 833820bbbf470c1814d0057b25e9c8fd 225 Gene3D G3DSA:3.40.1160.10 1 225 1.2E-62 T 31-10-2018 IPR036393 Acetylglutamate kinase-like superfamily TK0305 833820bbbf470c1814d0057b25e9c8fd 225 SUPERFAMILY SSF53633 1 224 6.28E-52 T 31-10-2018 IPR036393 Acetylglutamate kinase-like superfamily TK0305 833820bbbf470c1814d0057b25e9c8fd 225 TIGRFAM TIGR02076 pyrH_arch: putative uridylate kinase 3 224 4.5E-88 T 31-10-2018 IPR011818 Uridylate kinase, archaeal/spirochete, putative GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 TK0305 833820bbbf470c1814d0057b25e9c8fd 225 Pfam PF00696 Amino acid kinase family 1 202 7.1E-35 T 31-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 TK0157 796ebb641d89bf1144ca6d89624c96e4 457 Pfam PF00860 Permease family 20 413 3.5E-37 T 31-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 TK0157 796ebb641d89bf1144ca6d89624c96e4 457 PIRSF PIRSF005353 1 454 3.5E-160 T 31-10-2018 IPR026033 Purine permease PbuG-like TK0916 0ff9eb1d444de02410ffa39474bec08f 350 TIGRFAM TIGR00692 tdh: L-threonine 3-dehydrogenase 7 346 1.9E-180 T 31-10-2018 IPR004627 L-threonine 3-dehydrogenase GO:0006567|GO:0008270|GO:0008743|GO:0055114 KEGG: 00260+1.1.1.103|MetaCyc: PWY-7378 TK0916 0ff9eb1d444de02410ffa39474bec08f 350 Gene3D G3DSA:3.40.50.720 157 291 6.1E-136 T 31-10-2018 TK0916 0ff9eb1d444de02410ffa39474bec08f 350 Hamap MF_00627 L-threonine 3-dehydrogenase [tdh]. 5 347 54.195 T 31-10-2018 IPR004627 L-threonine 3-dehydrogenase GO:0006567|GO:0008270|GO:0008743|GO:0055114 KEGG: 00260+1.1.1.103|MetaCyc: PWY-7378 TK0916 0ff9eb1d444de02410ffa39474bec08f 350 SUPERFAMILY SSF51735 146 310 2.37E-34 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily TK0916 0ff9eb1d444de02410ffa39474bec08f 350 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 138 2.4E-36 T 31-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 TK0916 0ff9eb1d444de02410ffa39474bec08f 350 Gene3D G3DSA:3.90.180.10 21 338 6.1E-136 T 31-10-2018 TK0916 0ff9eb1d444de02410ffa39474bec08f 350 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 66 80 - T 31-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 TK0916 0ff9eb1d444de02410ffa39474bec08f 350 Pfam PF00107 Zinc-binding dehydrogenase 178 306 8.4E-29 T 31-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 TK0916 0ff9eb1d444de02410ffa39474bec08f 350 SUPERFAMILY SSF50129 3 177 2.59E-54 T 31-10-2018 IPR011032 GroES-like superfamily TK0916 0ff9eb1d444de02410ffa39474bec08f 350 SMART SM00829 16 345 1.9E-6 T 31-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 TK1269 a7b48d6fa08278d5b80122b4b8705d9a 487 Gene3D G3DSA:3.40.50.720 1 140 1.8E-19 T 31-10-2018 TK1269 a7b48d6fa08278d5b80122b4b8705d9a 487 Pfam PF02254 TrkA-N domain 3 106 3.9E-18 T 31-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 TK1269 a7b48d6fa08278d5b80122b4b8705d9a 487 SUPERFAMILY SSF51735 1 138 4.25E-20 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily TK1269 a7b48d6fa08278d5b80122b4b8705d9a 487 SUPERFAMILY SSF64182 162 453 2.49E-59 T 31-10-2018 IPR038763 DHH phosphoesterase superfamily TK1269 a7b48d6fa08278d5b80122b4b8705d9a 487 Gene3D G3DSA:3.90.1640.10 163 366 4.1E-28 T 31-10-2018 TK1269 a7b48d6fa08278d5b80122b4b8705d9a 487 Pfam PF01368 DHH family 166 315 2.6E-11 T 31-10-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 TK1269 a7b48d6fa08278d5b80122b4b8705d9a 487 Pfam PF02272 DHHA1 domain 356 474 2.6E-16 T 31-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 TK0805 b978eefd8a09a8f179c9974b2319f77f 228 TIGRFAM TIGR00729 TIGR00729: ribonuclease HII 3 205 2.2E-72 T 31-10-2018 IPR004649 Ribonuclease H2, subunit A GO:0004523|GO:0016070 TK0805 b978eefd8a09a8f179c9974b2319f77f 228 Hamap MF_00052_A Ribonuclease HII [rnhB]. 2 206 37.988 T 31-10-2018 IPR020787 Ribonuclease HII, archaea GO:0004523|GO:0005737|GO:0006401|GO:0030145 TK0805 b978eefd8a09a8f179c9974b2319f77f 228 Gene3D G3DSA:3.30.420.10 2 161 5.7E-63 T 31-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 TK0805 b978eefd8a09a8f179c9974b2319f77f 228 SUPERFAMILY SSF53098 2 209 2.43E-58 T 31-10-2018 IPR012337 Ribonuclease H-like superfamily TK0805 b978eefd8a09a8f179c9974b2319f77f 228 Pfam PF01351 Ribonuclease HII 4 200 7.9E-50 T 31-10-2018 IPR024567 Ribonuclease HII/HIII domain TK0805 b978eefd8a09a8f179c9974b2319f77f 228 Gene3D G3DSA:1.10.10.460 162 208 8.2E-26 T 31-10-2018 IPR023160 Ribonuclease HII, helix-loop-helix cap domain superfamily GO:0004523 TK0266 3ca8c6acc320a3059126e6bdaabcd776 213 Gene3D G3DSA:3.20.20.70 1 212 4.3E-52 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TK0266 3ca8c6acc320a3059126e6bdaabcd776 213 Hamap MF_00214 3-dehydroquinate dehydratase [aroD]. 1 211 31.255 T 31-10-2018 IPR001381 3-dehydroquinate dehydratase type I GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 TK0266 3ca8c6acc320a3059126e6bdaabcd776 213 Pfam PF01487 Type I 3-dehydroquinase 13 206 6.5E-48 T 31-10-2018 IPR001381 3-dehydroquinate dehydratase type I GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 TK0266 3ca8c6acc320a3059126e6bdaabcd776 213 SUPERFAMILY SSF51569 2 208 1.1E-53 T 31-10-2018 TK1083 811fbc32bc1e71eb88ffcc001bf08daa 1123 Gene3D G3DSA:3.90.1800.10 1013 1121 5.9E-41 T 31-10-2018 TK1083 811fbc32bc1e71eb88ffcc001bf08daa 1123 Pfam PF04565 RNA polymerase Rpb2, domain 3 425 489 4.9E-30 T 31-10-2018 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TK1083 811fbc32bc1e71eb88ffcc001bf08daa 1123 TIGRFAM TIGR03670 rpoB_arch: DNA-directed RNA polymerase subunit B 522 1122 0.0 T 31-10-2018 IPR019969 DNA-directed RNA polymerase subunit B (Rpo2) GO:0003677|GO:0003899|GO:0006351|GO:0008270 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TK1083 811fbc32bc1e71eb88ffcc001bf08daa 1123 Pfam PF04566 RNA polymerase Rpb2, domain 4 522 585 1.8E-19 T 31-10-2018 IPR007646 RNA polymerase Rpb2, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TK1083 811fbc32bc1e71eb88ffcc001bf08daa 1123 Gene3D G3DSA:2.40.270.10 654 1008 3.9E-146 T 31-10-2018 IPR037033 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TK1083 811fbc32bc1e71eb88ffcc001bf08daa 1123 Pfam PF04560 RNA polymerase Rpb2, domain 7 1028 1118 9.2E-31 T 31-10-2018 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TK1083 811fbc32bc1e71eb88ffcc001bf08daa 1123 ProSitePatterns PS01166 RNA polymerases beta chain signature. 879 891 - T 31-10-2018 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TK1083 811fbc32bc1e71eb88ffcc001bf08daa 1123 Gene3D G3DSA:3.90.1110.10 181 337 6.9E-61 T 31-10-2018 IPR037034 RNA polymerase Rpb2, domain 2 superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TK1083 811fbc32bc1e71eb88ffcc001bf08daa 1123 Pfam PF00562 RNA polymerase Rpb2, domain 6 654 1026 4.3E-132 T 31-10-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TK1083 811fbc32bc1e71eb88ffcc001bf08daa 1123 Pfam PF04561 RNA polymerase Rpb2, domain 2 176 349 7.4E-41 T 31-10-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TK1083 811fbc32bc1e71eb88ffcc001bf08daa 1123 Pfam PF04563 RNA polymerase beta subunit 30 382 7.6E-54 T 31-10-2018 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TK1083 811fbc32bc1e71eb88ffcc001bf08daa 1123 Pfam PF04567 RNA polymerase Rpb2, domain 5 606 638 9.0E-9 T 31-10-2018 IPR007647 RNA polymerase Rpb2, domain 5 GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TK1083 811fbc32bc1e71eb88ffcc001bf08daa 1123 Gene3D G3DSA:3.90.1100.10 338 514 1.2E-55 T 31-10-2018 TK1083 811fbc32bc1e71eb88ffcc001bf08daa 1123 SUPERFAMILY SSF64484 10 1121 0.0 T 31-10-2018 TK1083 811fbc32bc1e71eb88ffcc001bf08daa 1123 Gene3D G3DSA:3.90.1100.10 22 180 1.6E-12 T 31-10-2018 TK1083 811fbc32bc1e71eb88ffcc001bf08daa 1123 Gene3D G3DSA:2.40.50.150 684 875 3.9E-146 T 31-10-2018 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TK1081 1142f2f249e9f3455a789d500d2d70dc 391 SUPERFAMILY SSF64484 30 384 1.97E-105 T 31-10-2018 TK1081 1142f2f249e9f3455a789d500d2d70dc 391 Pfam PF04998 RNA polymerase Rpb1, domain 5 49 332 6.4E-56 T 31-10-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TK1081 1142f2f249e9f3455a789d500d2d70dc 391 TIGRFAM TIGR02389 RNA_pol_rpoA2: DNA-directed RNA polymerase, subunit A'' 16 382 5.9E-150 T 31-10-2018 IPR012757 DNA-directed RNA polymerase subunit A'' GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TK1081 1142f2f249e9f3455a789d500d2d70dc 391 Gene3D G3DSA:1.10.150.390 333 378 1.6E-22 T 31-10-2018 TK1081 1142f2f249e9f3455a789d500d2d70dc 391 Hamap MF_00411 DNA-directed RNA polymerase subunit A'' [rpoA2]. 3 385 41.189 T 31-10-2018 IPR012757 DNA-directed RNA polymerase subunit A'' GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TK1491 07c57fa03e50c724c9700028e8b52ec3 149 SMART SM00344 2 108 6.0E-44 T 31-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 TK1491 07c57fa03e50c724c9700028e8b52ec3 149 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 29 48 2.0E-17 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TK1491 07c57fa03e50c724c9700028e8b52ec3 149 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 2 18 2.0E-17 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TK1491 07c57fa03e50c724c9700028e8b52ec3 149 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 18 29 2.0E-17 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TK1491 07c57fa03e50c724c9700028e8b52ec3 149 SUPERFAMILY SSF54909 62 145 6.84E-16 T 31-10-2018 IPR011008 Dimeric alpha-beta barrel TK1491 07c57fa03e50c724c9700028e8b52ec3 149 Pfam PF01037 Lrp/AsnC ligand binding domain 68 137 1.8E-12 T 31-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain TK1491 07c57fa03e50c724c9700028e8b52ec3 149 Pfam PF13412 Winged helix-turn-helix DNA-binding 3 49 9.1E-19 T 31-10-2018 TK1491 07c57fa03e50c724c9700028e8b52ec3 149 Gene3D G3DSA:1.10.10.10 1 52 1.7E-22 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TK1491 07c57fa03e50c724c9700028e8b52ec3 149 SUPERFAMILY SSF46785 2 62 6.69E-19 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TK1491 07c57fa03e50c724c9700028e8b52ec3 149 Gene3D G3DSA:3.30.70.920 54 147 2.1E-21 T 31-10-2018 TK1898 982bafefcbd2f772a0b4d002d08bb8dc 252 Gene3D G3DSA:3.40.1350.10 126 238 1.6E-42 T 31-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 TK1898 982bafefcbd2f772a0b4d002d08bb8dc 252 Hamap MF_00722 Endonuclease NucS [nucS]. 30 243 38.716 T 31-10-2018 IPR002793 Endonuclease NucS GO:0004519 TK1898 982bafefcbd2f772a0b4d002d08bb8dc 252 Gene3D G3DSA:2.70.180.20 3 125 2.0E-44 T 31-10-2018 TK1898 982bafefcbd2f772a0b4d002d08bb8dc 252 Pfam PF01939 Endonuclease NucS 29 245 5.5E-87 T 31-10-2018 IPR002793 Endonuclease NucS GO:0004519 TK0217 68440924cd32c53c680a5b90be2922fc 335 PIRSF PIRSF029271 3 335 5.9E-149 T 31-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 TK0217 68440924cd32c53c680a5b90be2922fc 335 TIGRFAM TIGR00343 TIGR00343: pyridoxal 5'-phosphate synthase, synthase subunit Pdx1 15 334 1.9E-146 T 31-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 TK0217 68440924cd32c53c680a5b90be2922fc 335 SUPERFAMILY SSF51366 24 310 1.13E-61 T 31-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 TK0217 68440924cd32c53c680a5b90be2922fc 335 Pfam PF05690 Thiazole biosynthesis protein ThiG 245 299 2.6E-8 T 31-10-2018 IPR033983 Thiazole synthase ThiG KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 TK0217 68440924cd32c53c680a5b90be2922fc 335 Gene3D G3DSA:3.20.20.70 1 316 1.1E-154 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TK0217 68440924cd32c53c680a5b90be2922fc 335 Pfam PF01680 SOR/SNZ family 13 213 5.4E-96 T 31-10-2018 IPR033755 PdxS/SNZ N-terminal domain KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 TK0217 68440924cd32c53c680a5b90be2922fc 335 Hamap MF_01824 Pyridoxal 5'-phosphate synthase subunit PdxS [pdxS]. 10 335 53.732 T 31-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 TK0217 68440924cd32c53c680a5b90be2922fc 335 ProSitePatterns PS01235 PdxS/SNZ family signature. 248 266 - T 31-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 TK0433 325649a56d74f1a6c78e57053ab5bb7e 428 TIGRFAM TIGR00190 thiC: phosphomethylpyrimidine synthase 1 422 1.3E-188 T 31-10-2018 IPR002817 Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 TK0433 325649a56d74f1a6c78e57053ab5bb7e 428 Hamap MF_00089 Phosphomethylpyrimidine synthase [thiC]. 1 425 87.936 T 31-10-2018 IPR037509 Phosphomethylpyrimidine synthase GO:0009228|GO:0016830 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 TK0433 325649a56d74f1a6c78e57053ab5bb7e 428 Gene3D G3DSA:3.20.20.540 44 362 1.7E-138 T 31-10-2018 IPR038521 ThiC/Bza superfamily KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 TK0433 325649a56d74f1a6c78e57053ab5bb7e 428 Pfam PF01964 Radical SAM ThiC family 2 420 1.8E-182 T 31-10-2018 IPR002817 Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 TK1247 9ef7729b64737ad440644d1eb8eede3e 436 Pfam PF02163 Peptidase family M50 323 366 2.4E-8 T 31-10-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 TK0356 c7ed884d9639d31ea17a1d300e0cd4fa 708 PIRSF PIRSF019317 1 708 0.0 T 31-10-2018 IPR014501 Uncharacterised conserved protein UCP019317 TK0356 c7ed884d9639d31ea17a1d300e0cd4fa 708 Gene3D G3DSA:2.60.40.1120 381 453 1.0E-6 T 31-10-2018 TK0356 c7ed884d9639d31ea17a1d300e0cd4fa 708 Pfam PF10633 NPCBM-associated, NEW3 domain of alpha-galactosidase 597 663 1.2E-6 T 31-10-2018 IPR018905 Alpha-galactosidase, NEW3 domain TK0827 dba26ce74eaf2297897d3ea571719a3c 390 Gene3D G3DSA:1.20.1250.20 10 200 6.0E-15 T 31-10-2018 TK0827 dba26ce74eaf2297897d3ea571719a3c 390 Pfam PF07690 Major Facilitator Superfamily 21 348 1.3E-17 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TK0827 dba26ce74eaf2297897d3ea571719a3c 390 SUPERFAMILY SSF103473 11 386 9.94E-41 T 31-10-2018 IPR036259 MFS transporter superfamily TK0827 dba26ce74eaf2297897d3ea571719a3c 390 ProSitePatterns PS00217 Sugar transport proteins signature 2. 104 129 - T 31-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 TK0827 dba26ce74eaf2297897d3ea571719a3c 390 Gene3D G3DSA:1.20.1250.20 210 389 1.6E-13 T 31-10-2018 TK1968 c8d7f8d5a87bbfdacd1f7188032168c2 309 SUPERFAMILY SSF48179 174 296 1.26E-27 T 31-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 TK1968 c8d7f8d5a87bbfdacd1f7188032168c2 309 Gene3D G3DSA:3.40.50.720 1 171 1.8E-70 T 31-10-2018 TK1968 c8d7f8d5a87bbfdacd1f7188032168c2 309 SUPERFAMILY SSF51735 1 150 2.54E-21 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily TK1968 c8d7f8d5a87bbfdacd1f7188032168c2 309 Pfam PF02558 Ketopantoate reductase PanE/ApbA 3 146 2.5E-38 T 31-10-2018 IPR013332 Ketopantoate reductase, N-terminal domain TK1968 c8d7f8d5a87bbfdacd1f7188032168c2 309 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 2 296 8.1E-84 T 31-10-2018 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0008677|GO:0015940 KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 TK1968 c8d7f8d5a87bbfdacd1f7188032168c2 309 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 174 295 7.8E-31 T 31-10-2018 IPR013752 Ketopantoate reductase, C-terminal domain TK1968 c8d7f8d5a87bbfdacd1f7188032168c2 309 Gene3D G3DSA:1.10.1040.10 172 296 1.7E-42 T 31-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 TK0940 083cfaab9e7ecbe05e10d08cbfecc4e1 263 Gene3D G3DSA:1.10.340.30 41 186 6.1E-81 T 31-10-2018 TK0940 083cfaab9e7ecbe05e10d08cbfecc4e1 263 PIRSF PIRSF008955 12 263 4.1E-112 T 31-10-2018 IPR016544 N-glycosylase/DNA lyase GO:0000702|GO:0003906|GO:0006284 TK0940 083cfaab9e7ecbe05e10d08cbfecc4e1 263 SUPERFAMILY SSF48150 16 254 1.18E-84 T 31-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 TK0940 083cfaab9e7ecbe05e10d08cbfecc4e1 263 Gene3D G3DSA:1.10.1670.10 25 244 6.1E-81 T 31-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 TK0940 083cfaab9e7ecbe05e10d08cbfecc4e1 263 Hamap MF_01168 N-glycosylase/DNA lyase. 20 257 41.805 T 31-10-2018 IPR016544 N-glycosylase/DNA lyase GO:0000702|GO:0003906|GO:0006284 TK0940 083cfaab9e7ecbe05e10d08cbfecc4e1 263 Pfam PF09171 N-glycosylase/DNA lyase 23 245 1.4E-88 T 31-10-2018 IPR015254 N-glycosylase/DNA lyase-like GO:0003906|GO:0016799 TK2261 40bbc6445d5fabb0d0aa73110b9a45c0 78 SMART SM00966 4 49 4.8E-16 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 TK2261 40bbc6445d5fabb0d0aa73110b9a45c0 78 Gene3D G3DSA:2.10.260.10 2 42 1.2E-17 T 31-10-2018 TK2261 40bbc6445d5fabb0d0aa73110b9a45c0 78 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 5 46 2.5E-13 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 TK2261 40bbc6445d5fabb0d0aa73110b9a45c0 78 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 4 45 2.7E-18 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 TK2261 40bbc6445d5fabb0d0aa73110b9a45c0 78 SUPERFAMILY SSF89447 1 74 1.13E-14 T 31-10-2018 IPR037914 SpoVT-AbrB domain superfamily TK2035 715945a2917d701e81210aed31571f8d 398 Gene3D G3DSA:4.10.1250.10 269 305 7.5E-10 T 31-10-2018 TK2035 715945a2917d701e81210aed31571f8d 398 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 293 383 1.8E-24 T 31-10-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 TK2035 715945a2917d701e81210aed31571f8d 398 PIRSF PIRSF006487 1 398 1.4E-106 T 31-10-2018 IPR028896 Aminomethyltransferase-like KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 TK2035 715945a2917d701e81210aed31571f8d 398 TIGRFAM TIGR00528 gcvT: glycine cleavage system T protein 3 387 2.4E-94 T 31-10-2018 IPR006223 Glycine cleavage system T protein GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 TK2035 715945a2917d701e81210aed31571f8d 398 Pfam PF01571 Aminomethyltransferase folate-binding domain 8 287 2.1E-97 T 31-10-2018 IPR006222 Aminomethyltransferase, folate-binding domain TK2035 715945a2917d701e81210aed31571f8d 398 Hamap MF_00259 Aminomethyltransferase [gcvT]. 1 389 43.564 T 31-10-2018 IPR022903 Glycine cleavage system T protein, bacteria GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 TK2035 715945a2917d701e81210aed31571f8d 398 SUPERFAMILY SSF101790 300 392 1.8E-25 T 31-10-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal TK2035 715945a2917d701e81210aed31571f8d 398 Gene3D G3DSA:3.30.1360.120 8 255 1.5E-90 T 31-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 TK2035 715945a2917d701e81210aed31571f8d 398 Gene3D G3DSA:2.40.30.110 310 383 8.9E-31 T 31-10-2018 TK2035 715945a2917d701e81210aed31571f8d 398 Gene3D G3DSA:3.30.70.1400 52 143 1.5E-90 T 31-10-2018 TK2035 715945a2917d701e81210aed31571f8d 398 SUPERFAMILY SSF103025 2 308 1.73E-95 T 31-10-2018 TK1262 1d85997db459b27560c2b51f1e7d3bc2 123 SUPERFAMILY SSF102712 2 121 4.84E-30 T 31-10-2018 TK1262 1d85997db459b27560c2b51f1e7d3bc2 123 Pfam PF14464 Prokaryotic homologs of the JAB domain 10 100 2.9E-11 T 31-10-2018 IPR028090 JAB domain, prokaryotic TK1262 1d85997db459b27560c2b51f1e7d3bc2 123 Gene3D G3DSA:3.40.140.10 2 123 6.8E-29 T 31-10-2018 TK1590 9e0ccca49a9b2e684f6b4ef49443aca3 248 PRINTS PR01874 DNA repair protein radA signature 14 42 5.1E-10 T 31-10-2018 TK1590 9e0ccca49a9b2e684f6b4ef49443aca3 248 PRINTS PR01874 DNA repair protein radA signature 135 159 5.1E-10 T 31-10-2018 TK1590 9e0ccca49a9b2e684f6b4ef49443aca3 248 PRINTS PR01874 DNA repair protein radA signature 56 73 5.1E-10 T 31-10-2018 TK1590 9e0ccca49a9b2e684f6b4ef49443aca3 248 Hamap MF_01076 UPF0273 protein . 2 245 63.617 T 31-10-2018 IPR022475 Uncharacterised protein family UPF0273, KaiC-like TK1590 9e0ccca49a9b2e684f6b4ef49443aca3 248 Gene3D G3DSA:3.40.50.300 1 247 3.0E-81 T 31-10-2018 TK1590 9e0ccca49a9b2e684f6b4ef49443aca3 248 Pfam PF06745 KaiC 5 237 3.4E-92 T 31-10-2018 IPR014774 KaiC-like domain TK1590 9e0ccca49a9b2e684f6b4ef49443aca3 248 TIGRFAM TIGR03877 thermo_KaiC_1: KaiC domain protein, Ph0284 family 2 239 6.4E-143 T 31-10-2018 IPR022475 Uncharacterised protein family UPF0273, KaiC-like TK1590 9e0ccca49a9b2e684f6b4ef49443aca3 248 SUPERFAMILY SSF52540 3 236 7.53E-49 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK1767 4c0d423b255978e99121dc7e32755640 120 Pfam PF01900 Rpp14/Pop5 family 17 113 1.8E-22 T 31-10-2018 IPR002759 Ribonuclease P/MRP protein subunit GO:0004540|GO:0008033 Reactome: R-HSA-6784531 TK1767 4c0d423b255978e99121dc7e32755640 120 Hamap MF_00755 Ribonuclease P protein component 2 [rnp2]. 5 116 27.21 T 31-10-2018 IPR002759 Ribonuclease P/MRP protein subunit GO:0004540|GO:0008033 Reactome: R-HSA-6784531 TK1767 4c0d423b255978e99121dc7e32755640 120 PIRSF PIRSF004952 4 120 1.9E-48 T 31-10-2018 IPR016434 Ribonuclease P, protein component 2 GO:0001682|GO:0004526 TK1767 4c0d423b255978e99121dc7e32755640 120 SUPERFAMILY SSF160350 4 116 1.7E-35 T 31-10-2018 IPR038085 Rnp2-like domain superfamily Reactome: R-HSA-6784531 TK1767 4c0d423b255978e99121dc7e32755640 120 Gene3D G3DSA:3.30.70.3250 1 120 1.2E-50 T 31-10-2018 IPR038085 Rnp2-like domain superfamily Reactome: R-HSA-6784531 TK2219 960c36379325f89a8340407fdfad974a 499 SMART SM00382 42 159 5.8E-12 T 31-10-2018 IPR003593 AAA+ ATPase domain TK2219 960c36379325f89a8340407fdfad974a 499 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 46 155 1.3E-15 T 31-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TK2219 960c36379325f89a8340407fdfad974a 499 Gene3D G3DSA:3.40.50.300 4 157 1.5E-38 T 31-10-2018 TK2219 960c36379325f89a8340407fdfad974a 499 SUPERFAMILY SSF52540 4 212 2.57E-46 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK2219 960c36379325f89a8340407fdfad974a 499 Hamap MF_01508 Replication factor C large subunit [rfcL]. 4 441 35.483 T 31-10-2018 IPR023935 Replication factor C, large subunit TK2219 960c36379325f89a8340407fdfad974a 499 Gene3D G3DSA:1.10.8.60 160 217 6.1E-11 T 31-10-2018 TK0364 b681c8845493c8e7bd21f3171ae6f099 221 SUPERFAMILY SSF53448 5 209 1.2E-51 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TK0364 b681c8845493c8e7bd21f3171ae6f099 221 Gene3D G3DSA:3.90.550.10 3 220 3.8E-59 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TK0364 b681c8845493c8e7bd21f3171ae6f099 221 Pfam PF00535 Glycosyl transferase family 2 8 167 1.0E-38 T 31-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TK0067 d5865fefbeb5b635ff423c84ce2d25cc 188 Hamap MF_00243 Nicotinamide-nucleotide adenylyltransferase. 1 188 92.132 T 31-10-2018 IPR006418 Nicotinamide-nucleotide adenylyltransferase, archaeal type GO:0000309|GO:0005737|GO:0009435 KEGG: 00760+2.7.7.1 TK0067 d5865fefbeb5b635ff423c84ce2d25cc 188 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 4 63 1.9E-18 T 31-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 TK0067 d5865fefbeb5b635ff423c84ce2d25cc 188 Pfam PF01467 Cytidylyltransferase-like 6 137 3.1E-19 T 31-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 TK0067 d5865fefbeb5b635ff423c84ce2d25cc 188 TIGRFAM TIGR01527 arch_NMN_Atrans: nicotinamide-nucleotide adenylyltransferase 4 169 7.4E-70 T 31-10-2018 IPR006418 Nicotinamide-nucleotide adenylyltransferase, archaeal type GO:0000309|GO:0005737|GO:0009435 KEGG: 00760+2.7.7.1 TK0067 d5865fefbeb5b635ff423c84ce2d25cc 188 Gene3D G3DSA:3.40.50.620 1 178 6.2E-55 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TK0067 d5865fefbeb5b635ff423c84ce2d25cc 188 SUPERFAMILY SSF52374 3 167 5.63E-37 T 31-10-2018 TK0435 0e61bb2d351e243216fad460f97fde7d 431 Gene3D G3DSA:3.40.225.10 257 431 1.0E-62 T 31-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily TK0435 0e61bb2d351e243216fad460f97fde7d 431 Gene3D G3DSA:3.40.1190.20 3 256 4.6E-69 T 31-10-2018 IPR029056 Ribokinase-like TK0435 0e61bb2d351e243216fad460f97fde7d 431 Pfam PF10120 Thiamine-phosphate synthase 263 427 1.9E-53 T 31-10-2018 IPR019293 Thiamine-phosphate synthase ThiN GO:0004789 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 TK0435 0e61bb2d351e243216fad460f97fde7d 431 SUPERFAMILY SSF53613 4 248 1.2E-56 T 31-10-2018 IPR029056 Ribokinase-like TK0435 0e61bb2d351e243216fad460f97fde7d 431 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 5 243 7.4E-65 T 31-10-2018 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 TK0435 0e61bb2d351e243216fad460f97fde7d 431 Pfam PF08543 Phosphomethylpyrimidine kinase 12 247 8.6E-70 T 31-10-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 TK0435 0e61bb2d351e243216fad460f97fde7d 431 SUPERFAMILY SSF53639 256 429 7.46E-55 T 31-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily TK0436 3731fc63836bf1fda1ec4f3d4419feb9 633 SUPERFAMILY SSF52540 420 629 5.5E-35 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK0436 3731fc63836bf1fda1ec4f3d4419feb9 633 Pfam PF00005 ABC transporter 436 572 2.3E-18 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TK0436 3731fc63836bf1fda1ec4f3d4419feb9 633 SMART SM00382 445 624 7.0E-13 T 31-10-2018 IPR003593 AAA+ ATPase domain TK0436 3731fc63836bf1fda1ec4f3d4419feb9 633 SUPERFAMILY SSF55729 276 368 3.06E-8 T 31-10-2018 IPR016181 Acyl-CoA N-acyltransferase TK0436 3731fc63836bf1fda1ec4f3d4419feb9 633 Gene3D G3DSA:3.40.630.30 221 349 3.6E-8 T 31-10-2018 TK0436 3731fc63836bf1fda1ec4f3d4419feb9 633 Pfam PF00583 Acetyltransferase (GNAT) family 275 339 2.3E-4 T 31-10-2018 IPR000182 GNAT domain TK0436 3731fc63836bf1fda1ec4f3d4419feb9 633 Gene3D G3DSA:3.40.50.300 415 633 8.4E-39 T 31-10-2018 TK1457 c00e034956c64f72a0f71f44046e60f6 205 Pfam PF01895 PhoU domain 19 101 2.8E-13 T 31-10-2018 IPR026022 PhoU domain TK1457 c00e034956c64f72a0f71f44046e60f6 205 Gene3D G3DSA:3.30.70.1450 118 205 1.0E-26 T 31-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 TK1457 c00e034956c64f72a0f71f44046e60f6 205 SUPERFAMILY SSF116726 109 192 1.7E-21 T 31-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 TK1457 c00e034956c64f72a0f71f44046e60f6 205 SUPERFAMILY SSF109755 6 122 8.76E-20 T 31-10-2018 TK1457 c00e034956c64f72a0f71f44046e60f6 205 Gene3D G3DSA:1.20.58.220 1 117 2.9E-29 T 31-10-2018 IPR038078 PhoU-like domain superfamily TK1457 c00e034956c64f72a0f71f44046e60f6 205 Pfam PF02080 TrkA-C domain 125 192 1.3E-13 T 31-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 TK2287 aa0a9973142a6c94f3148925edcd7540 306 PRINTS PR00685 Transcription initiation factor IIB signature 191 206 1.8E-58 T 31-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 TK2287 aa0a9973142a6c94f3148925edcd7540 306 PRINTS PR00685 Transcription initiation factor IIB signature 252 268 1.8E-58 T 31-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 TK2287 aa0a9973142a6c94f3148925edcd7540 306 PRINTS PR00685 Transcription initiation factor IIB signature 22 42 1.8E-58 T 31-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 TK2287 aa0a9973142a6c94f3148925edcd7540 306 PRINTS PR00685 Transcription initiation factor IIB signature 218 236 1.8E-58 T 31-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 TK2287 aa0a9973142a6c94f3148925edcd7540 306 PRINTS PR00685 Transcription initiation factor IIB signature 44 57 1.8E-58 T 31-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 TK2287 aa0a9973142a6c94f3148925edcd7540 306 PRINTS PR00685 Transcription initiation factor IIB signature 165 184 1.8E-58 T 31-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 TK2287 aa0a9973142a6c94f3148925edcd7540 306 PRINTS PR00685 Transcription initiation factor IIB signature 284 298 1.8E-58 T 31-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 TK2287 aa0a9973142a6c94f3148925edcd7540 306 PRINTS PR00685 Transcription initiation factor IIB signature 57 78 1.8E-58 T 31-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 TK2287 aa0a9973142a6c94f3148925edcd7540 306 SMART SM00385 123 204 2.4E-13 T 31-10-2018 IPR013763 Cyclin-like TK2287 aa0a9973142a6c94f3148925edcd7540 306 SMART SM00385 217 298 8.1E-11 T 31-10-2018 IPR013763 Cyclin-like TK2287 aa0a9973142a6c94f3148925edcd7540 306 ProSitePatterns PS00782 Transcription factor TFIIB repeat signature. 251 266 - T 31-10-2018 IPR023486 Transcription factor TFIIB, conserved site Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-674695|Reactome: R-HSA-6807505|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-76042 TK2287 aa0a9973142a6c94f3148925edcd7540 306 SUPERFAMILY SSF57783 7 53 8.5E-18 T 31-10-2018 TK2287 aa0a9973142a6c94f3148925edcd7540 306 SUPERFAMILY SSF47954 214 305 1.29E-28 T 31-10-2018 IPR036915 Cyclin-like superfamily TK2287 aa0a9973142a6c94f3148925edcd7540 306 Gene3D G3DSA:1.10.472.170 9 205 2.4E-66 T 31-10-2018 TK2287 aa0a9973142a6c94f3148925edcd7540 306 Gene3D G3DSA:1.10.472.10 214 306 2.9E-26 T 31-10-2018 TK2287 aa0a9973142a6c94f3148925edcd7540 306 Pfam PF00382 Transcription factor TFIIB repeat 219 289 8.9E-19 T 31-10-2018 IPR013150 Transcription factor TFIIB, cyclin-like domain GO:0017025 TK2287 aa0a9973142a6c94f3148925edcd7540 306 Pfam PF00382 Transcription factor TFIIB repeat 126 195 4.2E-19 T 31-10-2018 IPR013150 Transcription factor TFIIB, cyclin-like domain GO:0017025 TK2287 aa0a9973142a6c94f3148925edcd7540 306 Pfam PF08271 TFIIB zinc-binding 9 50 1.2E-19 T 31-10-2018 IPR013137 Zinc finger, TFIIB-type TK2287 aa0a9973142a6c94f3148925edcd7540 306 ProSitePatterns PS00782 Transcription factor TFIIB repeat signature. 157 172 - T 31-10-2018 IPR023486 Transcription factor TFIIB, conserved site Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-674695|Reactome: R-HSA-6807505|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-76042 TK2287 aa0a9973142a6c94f3148925edcd7540 306 SUPERFAMILY SSF47954 117 210 4.02E-26 T 31-10-2018 IPR036915 Cyclin-like superfamily TK2287 aa0a9973142a6c94f3148925edcd7540 306 Hamap MF_00383 Transcription initiation factor IIB [tfb]. 4 304 46.712 T 31-10-2018 IPR023484 Transcription initiation factor TFIIB, archaea TK0750 e61ef0429db484cf18a0428edc63aa8a 153 SUPERFAMILY SSF47113 1 153 9.67E-57 T 31-10-2018 IPR009072 Histone-fold GO:0046982 TK0750 e61ef0429db484cf18a0428edc63aa8a 153 Pfam PF09123 Domain of unknown function (DUF1931) 11 150 1.7E-48 T 31-10-2018 IPR015207 Protein of unknown function DUF1931 TK0750 e61ef0429db484cf18a0428edc63aa8a 153 Gene3D G3DSA:1.10.20.10 5 153 1.9E-39 T 31-10-2018 IPR009072 Histone-fold GO:0046982 TK1402 4e27a13d19beec1afe03c41e786a3e2a 269 Pfam PF10096 Uncharacterized protein conserved in bacteria (DUF2334) 57 257 4.7E-40 T 31-10-2018 IPR018763 Protein of unknown function DUF2334 TK1402 4e27a13d19beec1afe03c41e786a3e2a 269 SUPERFAMILY SSF88713 56 262 3.34E-19 T 31-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 TK1402 4e27a13d19beec1afe03c41e786a3e2a 269 Gene3D G3DSA:3.20.20.370 32 266 9.0E-16 T 31-10-2018 TK0253 e231dd0f58414c75990a9e6c71b5c0ac 325 Gene3D G3DSA:1.20.970.10 4 176 3.5E-113 T 31-10-2018 TK0253 e231dd0f58414c75990a9e6c71b5c0ac 325 TIGRFAM TIGR01245 trpD: anthranilate phosphoribosyltransferase 4 320 5.4E-115 T 31-10-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 TK0253 e231dd0f58414c75990a9e6c71b5c0ac 325 Pfam PF02885 Glycosyl transferase family, helical bundle domain 3 61 2.0E-12 T 31-10-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 TK0253 e231dd0f58414c75990a9e6c71b5c0ac 325 Pfam PF00591 Glycosyl transferase family, a/b domain 68 311 7.6E-81 T 31-10-2018 IPR000312 Glycosyl transferase, family 3 GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 TK0253 e231dd0f58414c75990a9e6c71b5c0ac 325 SUPERFAMILY SSF47648 2 65 1.13E-13 T 31-10-2018 IPR036320 Glycosyl transferase family 3, N-terminal domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 TK0253 e231dd0f58414c75990a9e6c71b5c0ac 325 Gene3D G3DSA:3.40.1030.10 67 306 3.5E-113 T 31-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 TK0253 e231dd0f58414c75990a9e6c71b5c0ac 325 SUPERFAMILY SSF52418 68 318 1.22E-80 T 31-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 TK0253 e231dd0f58414c75990a9e6c71b5c0ac 325 Hamap MF_00211 Anthranilate phosphoribosyltransferase [trpD]. 2 322 37.188 T 31-10-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 TK0567 9ade81e14f8350c598796d0398552a34 166 Pfam PF01037 Lrp/AsnC ligand binding domain 78 131 1.0E-8 T 31-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain TK0567 9ade81e14f8350c598796d0398552a34 166 Pfam PF13412 Winged helix-turn-helix DNA-binding 5 51 1.6E-14 T 31-10-2018 TK0567 9ade81e14f8350c598796d0398552a34 166 ProSitePatterns PS00519 AsnC-type HTH domain signature. 22 48 - T 31-10-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site TK0567 9ade81e14f8350c598796d0398552a34 166 SMART SM00344 4 112 9.0E-29 T 31-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 TK0567 9ade81e14f8350c598796d0398552a34 166 SUPERFAMILY SSF54909 68 146 7.64E-7 T 31-10-2018 IPR011008 Dimeric alpha-beta barrel TK0567 9ade81e14f8350c598796d0398552a34 166 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 20 31 4.9E-16 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TK0567 9ade81e14f8350c598796d0398552a34 166 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 31 50 4.9E-16 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TK0567 9ade81e14f8350c598796d0398552a34 166 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 4 20 4.9E-16 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TK0567 9ade81e14f8350c598796d0398552a34 166 Gene3D G3DSA:1.10.10.10 2 57 3.1E-19 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TK0567 9ade81e14f8350c598796d0398552a34 166 Gene3D G3DSA:3.30.70.920 58 148 2.4E-11 T 31-10-2018 TK0567 9ade81e14f8350c598796d0398552a34 166 SUPERFAMILY SSF46785 4 62 1.15E-14 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TK0064 f37e6ba4e3d8f2f2c5b00a999c343cdb 126 Gene3D G3DSA:1.20.120.330 5 126 6.5E-28 T 31-10-2018 TK0064 f37e6ba4e3d8f2f2c5b00a999c343cdb 126 SUPERFAMILY SSF81593 12 125 7.85E-6 T 31-10-2018 TK0064 f37e6ba4e3d8f2f2c5b00a999c343cdb 126 Pfam PF05168 HEPN domain 9 124 2.7E-24 T 31-10-2018 IPR007842 HEPN domain TK1574 b9bc24ddb96bf5b28a3712509912a04c 595 Pfam PF00583 Acetyltransferase (GNAT) family 463 565 4.8E-9 T 31-10-2018 IPR000182 GNAT domain TK1574 b9bc24ddb96bf5b28a3712509912a04c 595 SMART SM00729 83 378 2.3E-48 T 31-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TK1574 b9bc24ddb96bf5b28a3712509912a04c 595 SUPERFAMILY SSF55729 448 572 1.44E-10 T 31-10-2018 IPR016181 Acyl-CoA N-acyltransferase TK1574 b9bc24ddb96bf5b28a3712509912a04c 595 PIRSF PIRSF005669 1 577 1.5E-249 T 31-10-2018 IPR034687 Elongator complex protein 3-like Reactome: R-HSA-3214847 TK1574 b9bc24ddb96bf5b28a3712509912a04c 595 TIGRFAM TIGR01211 ELP3: radical SAM enzyme/protein acetyltransferase, ELP3 family 17 576 2.0E-264 T 31-10-2018 IPR034687 Elongator complex protein 3-like Reactome: R-HSA-3214847 TK1574 b9bc24ddb96bf5b28a3712509912a04c 595 Pfam PF16199 Radical_SAM C-terminal domain 339 418 3.2E-27 T 31-10-2018 IPR032432 Radical SAM, C-terminal extension Reactome: R-HSA-3214847 TK1574 b9bc24ddb96bf5b28a3712509912a04c 595 Pfam PF04055 Radical SAM superfamily 90 323 1.0E-32 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TK1574 b9bc24ddb96bf5b28a3712509912a04c 595 Gene3D G3DSA:3.80.30.20 236 386 2.3E-13 T 31-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe TK1574 b9bc24ddb96bf5b28a3712509912a04c 595 SUPERFAMILY SSF102114 88 385 7.32E-35 T 31-10-2018 TK1574 b9bc24ddb96bf5b28a3712509912a04c 595 Gene3D G3DSA:3.40.630.30 425 576 6.0E-9 T 31-10-2018 TK1199 20d07f9ab0f84870eaf99e00525aca5a 440 Gene3D G3DSA:2.40.50.360 119 243 3.5E-114 T 31-10-2018 TK1199 20d07f9ab0f84870eaf99e00525aca5a 440 SUPERFAMILY SSF50249 126 207 2.4E-19 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold TK1199 20d07f9ab0f84870eaf99e00525aca5a 440 SUPERFAMILY SSF52540 37 423 6.81E-41 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK1199 20d07f9ab0f84870eaf99e00525aca5a 440 Pfam PF06068 TIP49 C-terminus 14 403 3.2E-162 T 31-10-2018 IPR010339 TIP49, C-terminal GO:0003678|GO:0005524 Reactome: R-HSA-171319|Reactome: R-HSA-3214847 TK1199 20d07f9ab0f84870eaf99e00525aca5a 440 SMART SM00382 62 353 3.6E-13 T 31-10-2018 IPR003593 AAA+ ATPase domain TK1199 20d07f9ab0f84870eaf99e00525aca5a 440 Gene3D G3DSA:1.10.8.60 354 438 6.4E-27 T 31-10-2018 TK1199 20d07f9ab0f84870eaf99e00525aca5a 440 Gene3D G3DSA:3.40.50.300 18 349 3.5E-114 T 31-10-2018 TK0218 b46b66c8a37b29ac1414168a54842902 277 TIGRFAM TIGR00078 nadC: nicotinate-nucleotide diphosphorylase (carboxylating) 7 273 1.8E-97 T 31-10-2018 IPR004393 Nicotinate-nucleotide pyrophosphorylase GO:0004514|GO:0019363 KEGG: 00760+2.4.2.19|MetaCyc: PWY-5316|MetaCyc: PWY-5653|MetaCyc: PWY-7342|Reactome: R-HSA-196807 TK0218 b46b66c8a37b29ac1414168a54842902 277 SUPERFAMILY SSF54675 5 103 3.3E-31 T 31-10-2018 TK0218 b46b66c8a37b29ac1414168a54842902 277 Gene3D G3DSA:3.20.20.70 120 263 1.0E-90 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TK0218 b46b66c8a37b29ac1414168a54842902 277 SUPERFAMILY SSF51690 104 273 2.55E-48 T 31-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 TK0218 b46b66c8a37b29ac1414168a54842902 277 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 16 102 5.3E-31 T 31-10-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 TK0218 b46b66c8a37b29ac1414168a54842902 277 Gene3D G3DSA:3.90.1170.20 10 271 1.0E-90 T 31-10-2018 IPR037128 Quinolinate phosphoribosyl transferase, N-terminal domain superfamily GO:0016763 Reactome: R-HSA-196807 TK0218 b46b66c8a37b29ac1414168a54842902 277 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 104 272 3.5E-51 T 31-10-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 Reactome: R-HSA-196807 TK0218 b46b66c8a37b29ac1414168a54842902 277 PIRSF PIRSF006250 3 276 2.5E-91 T 31-10-2018 IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD Reactome: R-HSA-196807 TK0837 17c4dbe5607b06eb6387535bd5316895 799 Gene3D G3DSA:3.40.50.1000 468 737 3.1E-99 T 31-10-2018 IPR023214 HAD superfamily TK0837 17c4dbe5607b06eb6387535bd5316895 799 Pfam PF00403 Heavy-metal-associated domain 74 135 1.9E-15 T 31-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 TK0837 17c4dbe5607b06eb6387535bd5316895 799 Pfam PF00403 Heavy-metal-associated domain 4 65 1.4E-14 T 31-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 TK0837 17c4dbe5607b06eb6387535bd5316895 799 TIGRFAM TIGR00003 TIGR00003: copper ion binding protein 2 66 2.3E-19 T 31-10-2018 IPR006122 Heavy metal-associated domain, copper ion-binding GO:0005507 Reactome: R-HSA-936837 TK0837 17c4dbe5607b06eb6387535bd5316895 799 TIGRFAM TIGR00003 TIGR00003: copper ion binding protein 75 135 2.2E-13 T 31-10-2018 IPR006122 Heavy metal-associated domain, copper ion-binding GO:0005507 Reactome: R-HSA-936837 TK0837 17c4dbe5607b06eb6387535bd5316895 799 SUPERFAMILY SSF81653 290 386 9.55E-32 T 31-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 TK0837 17c4dbe5607b06eb6387535bd5316895 799 PRINTS PR00943 Copper-transporting ATPase signature 409 423 5.8E-11 T 31-10-2018 TK0837 17c4dbe5607b06eb6387535bd5316895 799 PRINTS PR00943 Copper-transporting ATPase signature 256 275 5.8E-11 T 31-10-2018 TK0837 17c4dbe5607b06eb6387535bd5316895 799 PRINTS PR00943 Copper-transporting ATPase signature 662 679 5.8E-11 T 31-10-2018 TK0837 17c4dbe5607b06eb6387535bd5316895 799 PRINTS PR00943 Copper-transporting ATPase signature 116 136 5.8E-11 T 31-10-2018 TK0837 17c4dbe5607b06eb6387535bd5316895 799 PRINTS PR00943 Copper-transporting ATPase signature 719 733 5.8E-11 T 31-10-2018 TK0837 17c4dbe5607b06eb6387535bd5316895 799 PRINTS PR00943 Copper-transporting ATPase signature 470 485 5.8E-11 T 31-10-2018 TK0837 17c4dbe5607b06eb6387535bd5316895 799 SUPERFAMILY SSF55008 73 138 1.2E-20 T 31-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 TK0837 17c4dbe5607b06eb6387535bd5316895 799 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 204 795 1.7E-182 T 31-10-2018 TK0837 17c4dbe5607b06eb6387535bd5316895 799 Gene3D G3DSA:3.30.70.100 68 136 1.1E-22 T 31-10-2018 TK0837 17c4dbe5607b06eb6387535bd5316895 799 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 259 765 8.3E-104 T 31-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 TK0837 17c4dbe5607b06eb6387535bd5316895 799 Pfam PF00702 haloacid dehalogenase-like hydrolase 485 699 7.4E-46 T 31-10-2018 TK0837 17c4dbe5607b06eb6387535bd5316895 799 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 223 794 8.4E-198 T 31-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 TK0837 17c4dbe5607b06eb6387535bd5316895 799 SUPERFAMILY SSF56784 485 792 4.34E-62 T 31-10-2018 IPR036412 HAD-like superfamily TK0837 17c4dbe5607b06eb6387535bd5316895 799 Gene3D G3DSA:3.30.70.100 1 66 9.2E-22 T 31-10-2018 TK0837 17c4dbe5607b06eb6387535bd5316895 799 Gene3D G3DSA:2.70.150.20 279 391 5.6E-46 T 31-10-2018 TK0837 17c4dbe5607b06eb6387535bd5316895 799 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 489 495 - T 31-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 TK0837 17c4dbe5607b06eb6387535bd5316895 799 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 336 350 2.5E-25 T 31-10-2018 TK0837 17c4dbe5607b06eb6387535bd5316895 799 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 708 720 2.5E-25 T 31-10-2018 TK0837 17c4dbe5607b06eb6387535bd5316895 799 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 487 501 2.5E-25 T 31-10-2018 TK0837 17c4dbe5607b06eb6387535bd5316895 799 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 685 704 2.5E-25 T 31-10-2018 TK0837 17c4dbe5607b06eb6387535bd5316895 799 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 610 621 2.5E-25 T 31-10-2018 TK0837 17c4dbe5607b06eb6387535bd5316895 799 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 632 642 2.5E-25 T 31-10-2018 TK0837 17c4dbe5607b06eb6387535bd5316895 799 SUPERFAMILY SSF81665 251 479 1.44E-13 T 31-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 TK0837 17c4dbe5607b06eb6387535bd5316895 799 Pfam PF00122 E1-E2 ATPase 287 465 2.2E-59 T 31-10-2018 TK0837 17c4dbe5607b06eb6387535bd5316895 799 Gene3D G3DSA:3.40.1110.10 498 617 3.1E-99 T 31-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 TK0837 17c4dbe5607b06eb6387535bd5316895 799 SUPERFAMILY SSF55008 1 67 2.49E-20 T 31-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 TK1465 4f44935797152f7a4c5abe6c5894df8e 455 SUPERFAMILY SSF52540 3 239 2.37E-38 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK1465 4f44935797152f7a4c5abe6c5894df8e 455 Pfam PF03008 Archaea bacterial proteins of unknown function 306 403 4.5E-29 T 31-10-2018 IPR004256 Domain of unknown function DUF234, DEXX-box ATPase C-terminal TK1465 4f44935797152f7a4c5abe6c5894df8e 455 Pfam PF01022 Bacterial regulatory protein, arsR family 240 282 1.0E-4 T 31-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TK1465 4f44935797152f7a4c5abe6c5894df8e 455 SUPERFAMILY SSF46785 221 352 1.55E-9 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TK1465 4f44935797152f7a4c5abe6c5894df8e 455 Pfam PF01637 ATPase domain predominantly from Archaea 5 198 2.0E-24 T 31-10-2018 IPR011579 ATPase domain GO:0005524 TK1465 4f44935797152f7a4c5abe6c5894df8e 455 Gene3D G3DSA:3.40.50.300 3 165 1.1E-30 T 31-10-2018 TK2192 25526c98975cc2db58ee3967d6c2313f 195 Gene3D G3DSA:3.40.50.300 6 194 1.1E-42 T 31-10-2018 TK2192 25526c98975cc2db58ee3967d6c2313f 195 SUPERFAMILY SSF52540 6 193 1.13E-20 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK2192 25526c98975cc2db58ee3967d6c2313f 195 Pfam PF13238 AAA domain 8 142 1.4E-18 T 31-10-2018 TK2253 7fda11e05904f4b3058e411b1cda7808 249 Gene3D G3DSA:3.30.70.1900 123 242 5.3E-37 T 31-10-2018 TK2253 7fda11e05904f4b3058e411b1cda7808 249 PIRSF PIRSF005054 1 242 9.5E-70 T 31-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 TK2253 7fda11e05904f4b3058e411b1cda7808 249 Gene3D G3DSA:3.30.70.1890 1 121 5.4E-42 T 31-10-2018 TK2253 7fda11e05904f4b3058e411b1cda7808 249 TIGRFAM TIGR01877 cas_cas6: CRISPR-associated endoribonuclease Cas6 50 237 2.6E-44 T 31-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 TK2253 7fda11e05904f4b3058e411b1cda7808 249 Pfam PF01881 CRISPR associated protein Cas6 94 238 1.8E-32 T 31-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 TK1876 ec5ac5537a21fd5e9d469d54b8dbaf40 280 SUPERFAMILY SSF103481 182 275 2.88E-11 T 31-10-2018 TK1876 ec5ac5537a21fd5e9d469d54b8dbaf40 280 Pfam PF00892 EamA-like transporter family 149 273 2.5E-15 T 31-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TK1876 ec5ac5537a21fd5e9d469d54b8dbaf40 280 Pfam PF00892 EamA-like transporter family 7 140 9.6E-15 T 31-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TK1876 ec5ac5537a21fd5e9d469d54b8dbaf40 280 SUPERFAMILY SSF103481 40 142 2.42E-11 T 31-10-2018 TK0697 8bf879425a36d43a5d6df6846e6944e8 219 Pfam PF04967 HTH DNA binding domain 163 215 1.2E-20 T 31-10-2018 IPR007050 Bacterioopsin activator-type, HTH domain TK2090 9ad783bbef5e95755b4cd3156bf4fa5b 189 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 50 166 4.6E-18 T 31-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TK2090 9ad783bbef5e95755b4cd3156bf4fa5b 189 SUPERFAMILY SSF143243 21 175 4.45E-27 T 31-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TK2090 9ad783bbef5e95755b4cd3156bf4fa5b 189 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 104 165 4.0E-27 T 31-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TK2090 9ad783bbef5e95755b4cd3156bf4fa5b 189 Gene3D G3DSA:3.30.460.80 22 148 4.9E-13 T 31-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TK2214 9a531d2ad15585c02f069fb21dd5d5b6 166 Gene3D G3DSA:3.40.630.30 16 164 1.1E-50 T 31-10-2018 TK2214 9a531d2ad15585c02f069fb21dd5d5b6 166 Pfam PF00583 Acetyltransferase (GNAT) family 28 137 2.0E-28 T 31-10-2018 IPR000182 GNAT domain TK2214 9a531d2ad15585c02f069fb21dd5d5b6 166 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 26 156 3.0E-37 T 31-10-2018 IPR006464 N-acetyltransferase RimI/Ard1 GO:0006474|GO:0016407 TK2214 9a531d2ad15585c02f069fb21dd5d5b6 166 SUPERFAMILY SSF55729 16 158 1.47E-40 T 31-10-2018 IPR016181 Acyl-CoA N-acyltransferase TK1246 bb6b450bc8e834dd5212b3220d593fca 183 Gene3D G3DSA:1.10.10.10 123 183 6.9E-7 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TK0669 6324b3a4014ffb4e44f2090cdf0f85eb 835 SMART SM01072 116 198 4.3E-15 T 31-10-2018 IPR004201 CDC48, domain 2 TK0669 6324b3a4014ffb4e44f2090cdf0f85eb 835 Gene3D G3DSA:1.10.8.60 377 418 3.5E-6 T 31-10-2018 TK0669 6324b3a4014ffb4e44f2090cdf0f85eb 835 ProSitePatterns PS00674 AAA-protein family signature. 346 364 - T 31-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 TK0669 6324b3a4014ffb4e44f2090cdf0f85eb 835 SMART SM01073 14 98 9.8E-37 T 31-10-2018 IPR003338 CDC48, N-terminal subdomain TK0669 6324b3a4014ffb4e44f2090cdf0f85eb 835 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 581 710 5.9E-49 T 31-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TK0669 6324b3a4014ffb4e44f2090cdf0f85eb 835 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 246 375 4.4E-51 T 31-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TK0669 6324b3a4014ffb4e44f2090cdf0f85eb 835 SMART SM00382 242 378 8.0E-26 T 31-10-2018 IPR003593 AAA+ ATPase domain TK0669 6324b3a4014ffb4e44f2090cdf0f85eb 835 SMART SM00382 577 713 3.5E-25 T 31-10-2018 IPR003593 AAA+ ATPase domain TK0669 6324b3a4014ffb4e44f2090cdf0f85eb 835 SUPERFAMILY SSF52540 539 815 1.07E-79 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK0669 6324b3a4014ffb4e44f2090cdf0f85eb 835 Pfam PF02933 Cell division protein 48 (CDC48), domain 2 121 198 4.0E-13 T 31-10-2018 IPR004201 CDC48, domain 2 TK0669 6324b3a4014ffb4e44f2090cdf0f85eb 835 Gene3D G3DSA:1.10.8.60 712 820 3.8E-31 T 31-10-2018 TK0669 6324b3a4014ffb4e44f2090cdf0f85eb 835 Pfam PF02359 Cell division protein 48 (CDC48), N-terminal domain 14 97 3.4E-30 T 31-10-2018 IPR003338 CDC48, N-terminal subdomain TK0669 6324b3a4014ffb4e44f2090cdf0f85eb 835 Gene3D G3DSA:3.40.50.300 535 710 1.6E-75 T 31-10-2018 TK0669 6324b3a4014ffb4e44f2090cdf0f85eb 835 Gene3D G3DSA:2.40.40.20 7 98 9.9E-33 T 31-10-2018 TK0669 6324b3a4014ffb4e44f2090cdf0f85eb 835 SUPERFAMILY SSF52540 204 529 1.81E-69 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK0669 6324b3a4014ffb4e44f2090cdf0f85eb 835 SUPERFAMILY SSF54585 98 211 6.87E-18 T 31-10-2018 IPR029067 CDC48 domain 2-like superfamily TK0669 6324b3a4014ffb4e44f2090cdf0f85eb 835 ProSitePatterns PS00674 AAA-protein family signature. 681 699 - T 31-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 TK0669 6324b3a4014ffb4e44f2090cdf0f85eb 835 TIGRFAM TIGR01243 CDC48: AAA family ATPase, CDC48 subfamily 13 821 0.0 T 31-10-2018 IPR005938 AAA ATPase, CDC48 family GO:0016787 Reactome: R-HSA-110320|Reactome: R-HSA-3371511|Reactome: R-HSA-382556|Reactome: R-HSA-532668|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5678895|Reactome: R-HSA-5689877|Reactome: R-HSA-5689896|Reactome: R-HSA-6798695|Reactome: R-HSA-8866654|Reactome: R-HSA-8876725 TK0669 6324b3a4014ffb4e44f2090cdf0f85eb 835 Gene3D G3DSA:3.40.50.300 195 375 1.4E-74 T 31-10-2018 TK0669 6324b3a4014ffb4e44f2090cdf0f85eb 835 SUPERFAMILY SSF50692 11 96 3.98E-27 T 31-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily TK0669 6324b3a4014ffb4e44f2090cdf0f85eb 835 Gene3D G3DSA:1.10.8.60 437 533 9.3E-16 T 31-10-2018 TK2052 81413f0d86e08ac2d939b2815ff9464b 75 SUPERFAMILY SSF54909 1 74 2.41E-18 T 31-10-2018 IPR011008 Dimeric alpha-beta barrel TK2052 81413f0d86e08ac2d939b2815ff9464b 75 Pfam PF01037 Lrp/AsnC ligand binding domain 9 74 1.2E-19 T 31-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain TK2052 81413f0d86e08ac2d939b2815ff9464b 75 Gene3D G3DSA:3.30.70.920 1 74 1.4E-27 T 31-10-2018 TK0864 4726add6785c9e3b2f9cb831be4ecac6 322 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 190 199 - T 31-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 TK0864 4726add6785c9e3b2f9cb831be4ecac6 322 Pfam PF00155 Aminotransferase class I and II 30 317 1.1E-33 T 31-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 TK0864 4726add6785c9e3b2f9cb831be4ecac6 322 Gene3D G3DSA:3.90.1150.10 21 317 4.1E-69 T 31-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TK0864 4726add6785c9e3b2f9cb831be4ecac6 322 Gene3D G3DSA:3.40.640.10 32 235 4.1E-69 T 31-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TK0864 4726add6785c9e3b2f9cb831be4ecac6 322 SUPERFAMILY SSF53383 10 318 3.94E-56 T 31-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TK1435 71693e57fc56821a3254eaf9f0db7d00 105 Pfam PF00543 Nitrogen regulatory protein P-II 4 97 1.7E-27 T 31-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 TK1435 71693e57fc56821a3254eaf9f0db7d00 105 SUPERFAMILY SSF54913 1 104 1.18E-34 T 31-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta TK1435 71693e57fc56821a3254eaf9f0db7d00 105 PRINTS PR00340 P-II protein signature 75 95 6.1E-23 T 31-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 TK1435 71693e57fc56821a3254eaf9f0db7d00 105 PRINTS PR00340 P-II protein signature 2 17 6.1E-23 T 31-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 TK1435 71693e57fc56821a3254eaf9f0db7d00 105 PRINTS PR00340 P-II protein signature 44 67 6.1E-23 T 31-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 TK1435 71693e57fc56821a3254eaf9f0db7d00 105 Gene3D G3DSA:3.30.70.120 1 105 8.1E-38 T 31-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal TK1435 71693e57fc56821a3254eaf9f0db7d00 105 SMART SM00938 4 97 3.3E-41 T 31-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 TK1650 48191541413435b557261581ae941fb9 178 Gene3D G3DSA:3.40.50.850 1 178 8.0E-74 T 31-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 TK1650 48191541413435b557261581ae941fb9 178 SUPERFAMILY SSF52499 3 177 2.62E-56 T 31-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 TK1650 48191541413435b557261581ae941fb9 178 Pfam PF00857 Isochorismatase family 5 176 1.2E-45 T 31-10-2018 IPR000868 Isochorismatase-like GO:0003824 TK0313 dec3b32bcee3dac0ce150452f4df9978 362 Gene3D G3DSA:3.30.70.360 158 267 3.2E-62 T 31-10-2018 TK0313 dec3b32bcee3dac0ce150452f4df9978 362 Pfam PF07687 Peptidase dimerisation domain 155 260 1.1E-8 T 31-10-2018 IPR011650 Peptidase M20, dimerisation domain TK0313 dec3b32bcee3dac0ce150452f4df9978 362 Pfam PF01546 Peptidase family M20/M25/M40 67 344 3.8E-25 T 31-10-2018 IPR002933 Peptidase M20 GO:0016787 TK0313 dec3b32bcee3dac0ce150452f4df9978 362 SUPERFAMILY SSF55031 163 265 6.28E-11 T 31-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain TK0313 dec3b32bcee3dac0ce150452f4df9978 362 Gene3D G3DSA:3.40.630.10 17 339 3.2E-62 T 31-10-2018 TK0313 dec3b32bcee3dac0ce150452f4df9978 362 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 90 127 - T 31-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 TK0313 dec3b32bcee3dac0ce150452f4df9978 362 SUPERFAMILY SSF53187 11 345 2.06E-42 T 31-10-2018 TK2153 2346fa57a74ac2050738b1d71b20567a 98 Pfam PF09876 Predicted metal-binding protein (DUF2103) 5 93 2.2E-23 T 31-10-2018 IPR018664 Protein of unknown function DUF2103, metal-binding TK0752 f90f50de03606168803ad8c7cd88f910 632 SUPERFAMILY SSF82171 23 366 1.83E-32 T 31-10-2018 TK0752 f90f50de03606168803ad8c7cd88f910 632 SUPERFAMILY SSF53474 374 631 1.32E-71 T 31-10-2018 IPR029058 Alpha/Beta hydrolase fold TK0752 f90f50de03606168803ad8c7cd88f910 632 Gene3D G3DSA:3.40.50.1820 379 632 1.3E-73 T 31-10-2018 IPR029058 Alpha/Beta hydrolase fold TK0752 f90f50de03606168803ad8c7cd88f910 632 Pfam PF07676 WD40-like Beta Propeller Repeat 56 89 3.1E-6 T 31-10-2018 IPR011659 WD40-like Beta Propeller TK0752 f90f50de03606168803ad8c7cd88f910 632 Gene3D G3DSA:2.120.10.30 149 378 3.7E-10 T 31-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like TK0752 f90f50de03606168803ad8c7cd88f910 632 Pfam PF00326 Prolyl oligopeptidase family 421 632 7.6E-60 T 31-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 TK0752 f90f50de03606168803ad8c7cd88f910 632 Gene3D G3DSA:2.120.10.30 16 143 7.4E-15 T 31-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like TK1684 ca7ea54c63f0d9d249e48f7e1eef779e 481 TIGRFAM TIGR01316 gltA: glutamate synthase (NADPH), homotetrameric 18 473 7.9E-226 T 31-10-2018 IPR006004 Glutamate synthase (NADPH), homotetrameric KEGG: 00195+1.18.1.2|MetaCyc: PWY-101 TK1684 ca7ea54c63f0d9d249e48f7e1eef779e 481 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 159 181 8.9E-17 T 31-10-2018 TK1684 ca7ea54c63f0d9d249e48f7e1eef779e 481 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 298 323 8.9E-17 T 31-10-2018 TK1684 ca7ea54c63f0d9d249e48f7e1eef779e 481 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 401 415 8.9E-17 T 31-10-2018 TK1684 ca7ea54c63f0d9d249e48f7e1eef779e 481 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 442 449 8.9E-17 T 31-10-2018 TK1684 ca7ea54c63f0d9d249e48f7e1eef779e 481 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 159 458 3.7E-41 T 31-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TK1684 ca7ea54c63f0d9d249e48f7e1eef779e 481 SUPERFAMILY SSF51971 159 408 1.06E-70 T 31-10-2018 TK1684 ca7ea54c63f0d9d249e48f7e1eef779e 481 SUPERFAMILY SSF46548 7 168 3.5E-31 T 31-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 TK1684 ca7ea54c63f0d9d249e48f7e1eef779e 481 Gene3D G3DSA:3.40.50.720 156 268 8.9E-26 T 31-10-2018 TK1684 ca7ea54c63f0d9d249e48f7e1eef779e 481 Gene3D G3DSA:1.10.1060.10 5 151 3.1E-39 T 31-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 TK1684 ca7ea54c63f0d9d249e48f7e1eef779e 481 Gene3D G3DSA:3.50.50.60 269 408 8.5E-46 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TK1684 ca7ea54c63f0d9d249e48f7e1eef779e 481 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 22 140 6.0E-39 T 31-10-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 TK1684 ca7ea54c63f0d9d249e48f7e1eef779e 481 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 243 261 2.9E-23 T 31-10-2018 TK1684 ca7ea54c63f0d9d249e48f7e1eef779e 481 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 298 316 2.9E-23 T 31-10-2018 TK1684 ca7ea54c63f0d9d249e48f7e1eef779e 481 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 160 179 2.9E-23 T 31-10-2018 TK1684 ca7ea54c63f0d9d249e48f7e1eef779e 481 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 427 449 2.9E-23 T 31-10-2018 TK1684 ca7ea54c63f0d9d249e48f7e1eef779e 481 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 400 416 2.9E-23 T 31-10-2018 TK0241 079f856a65652bb8b4bcba42ca6e79d9 147 SMART SM00195 4 146 1.9E-9 T 31-10-2018 IPR020422 Dual specificity protein phosphatase domain GO:0006470|GO:0008138 TK0241 079f856a65652bb8b4bcba42ca6e79d9 147 ProSitePatterns PS00383 Tyrosine specific protein phosphatases active site. 91 101 - T 31-10-2018 IPR016130 Protein-tyrosine phosphatase, active site GO:0004725|GO:0016311 TK0241 079f856a65652bb8b4bcba42ca6e79d9 147 PRINTS PR00700 Protein tyrosine phosphatase signature 88 106 1.9E-5 T 31-10-2018 IPR000242 PTP type protein phosphatase GO:0004725|GO:0006470 TK0241 079f856a65652bb8b4bcba42ca6e79d9 147 PRINTS PR00700 Protein tyrosine phosphatase signature 130 140 1.9E-5 T 31-10-2018 IPR000242 PTP type protein phosphatase GO:0004725|GO:0006470 TK0241 079f856a65652bb8b4bcba42ca6e79d9 147 PRINTS PR00700 Protein tyrosine phosphatase signature 114 129 1.9E-5 T 31-10-2018 IPR000242 PTP type protein phosphatase GO:0004725|GO:0006470 TK0241 079f856a65652bb8b4bcba42ca6e79d9 147 Gene3D G3DSA:3.90.190.10 6 147 1.8E-36 T 31-10-2018 IPR029021 Protein-tyrosine phosphatase-like TK0241 079f856a65652bb8b4bcba42ca6e79d9 147 SMART SM00404 52 142 1.4E-4 T 31-10-2018 IPR003595 Protein-tyrosine phosphatase, catalytic TK0241 079f856a65652bb8b4bcba42ca6e79d9 147 SUPERFAMILY SSF52799 28 144 6.67E-36 T 31-10-2018 IPR029021 Protein-tyrosine phosphatase-like TK0241 079f856a65652bb8b4bcba42ca6e79d9 147 Pfam PF00782 Dual specificity phosphatase, catalytic domain 50 145 2.5E-17 T 31-10-2018 IPR000340 Dual specificity phosphatase, catalytic domain GO:0008138|GO:0016311 TK0467 0df680bc492c679b83decf4d81c93e4c 1068 SUPERFAMILY SSF49899 479 664 4.65E-20 T 31-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily TK0467 0df680bc492c679b83decf4d81c93e4c 1068 TIGRFAM TIGR04288 CGP_CTERM: CGP-CTERM domain 1047 1066 2.6E-7 T 31-10-2018 IPR027552 CGP-CTERM domain TK0467 0df680bc492c679b83decf4d81c93e4c 1068 Gene3D G3DSA:2.60.120.200 475 592 9.6E-17 T 31-10-2018 TK0184 186452bc933e7d4d057052c20e20a13d 420 Gene3D G3DSA:1.10.287.660 131 243 6.1E-39 T 31-10-2018 IPR029012 Helix hairpin bin domain superfamily TK0184 186452bc933e7d4d057052c20e20a13d 420 SMART SM00931 130 182 1.5E-27 T 31-10-2018 IPR012976 NOSIC TK0184 186452bc933e7d4d057052c20e20a13d 420 Gene3D G3DSA:1.10.246.90 244 368 4.6E-53 T 31-10-2018 TK0184 186452bc933e7d4d057052c20e20a13d 420 Gene3D G3DSA:1.10.150.460 161 212 6.1E-39 T 31-10-2018 TK0184 186452bc933e7d4d057052c20e20a13d 420 SUPERFAMILY SSF89124 126 366 1.57E-81 T 31-10-2018 IPR036070 Nop domain superfamily TK0184 186452bc933e7d4d057052c20e20a13d 420 Gene3D G3DSA:3.30.420.220 1 125 7.0E-47 T 31-10-2018 TK0184 186452bc933e7d4d057052c20e20a13d 420 Pfam PF01798 snoRNA binding domain, fibrillarin 138 363 3.9E-73 T 31-10-2018 IPR002687 Nop domain TK2211 ced5cd1b05e1ac3033b620dce37a6f53 883 SMART SM00382 22 872 7.7E-4 T 31-10-2018 IPR003593 AAA+ ATPase domain TK2211 ced5cd1b05e1ac3033b620dce37a6f53 883 Pfam PF04423 Rad50 zinc hook motif 420 469 2.2E-15 T 31-10-2018 IPR013134 RAD50, zinc hook Reactome: R-HSA-2559586|Reactome: R-HSA-5685938|Reactome: R-HSA-5685939|Reactome: R-HSA-5685942|Reactome: R-HSA-5693548|Reactome: R-HSA-5693554|Reactome: R-HSA-5693565|Reactome: R-HSA-5693568|Reactome: R-HSA-5693571|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 TK2211 ced5cd1b05e1ac3033b620dce37a6f53 883 Pfam PF13476 AAA domain 5 296 2.1E-17 T 31-10-2018 IPR038729 Rad50/SbcC-type AAA domain TK2211 ced5cd1b05e1ac3033b620dce37a6f53 883 Gene3D G3DSA:1.10.287.510 391 502 2.4E-28 T 31-10-2018 TK2211 ced5cd1b05e1ac3033b620dce37a6f53 883 SUPERFAMILY SSF52540 1 246 5.58E-23 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK2211 ced5cd1b05e1ac3033b620dce37a6f53 883 SUPERFAMILY SSF75712 395 491 1.83E-19 T 31-10-2018 TK2211 ced5cd1b05e1ac3033b620dce37a6f53 883 Gene3D G3DSA:3.40.50.300 679 879 4.1E-43 T 31-10-2018 TK2211 ced5cd1b05e1ac3033b620dce37a6f53 883 Gene3D G3DSA:3.40.50.300 1 235 2.5E-44 T 31-10-2018 TK2211 ced5cd1b05e1ac3033b620dce37a6f53 883 SUPERFAMILY SSF52540 1 869 1.14E-33 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK2211 ced5cd1b05e1ac3033b620dce37a6f53 883 Hamap MF_00449 DNA double-strand break repair Rad50 ATPase [rad50]. 1 879 14.038 T 31-10-2018 IPR022982 DNA double-strand break repair Rad50 ATPase, archaeal type TK1287 06727e345df7aa32429971c12ecae337 230 TIGRFAM TIGR01091 upp: uracil phosphoribosyltransferase 15 218 1.6E-76 T 31-10-2018 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 TK1287 06727e345df7aa32429971c12ecae337 230 Pfam PF14681 Uracil phosphoribosyltransferase 15 217 1.2E-49 T 31-10-2018 TK1287 06727e345df7aa32429971c12ecae337 230 Gene3D G3DSA:3.40.50.2020 13 217 4.7E-59 T 31-10-2018 TK1287 06727e345df7aa32429971c12ecae337 230 Hamap MF_01218_A Uracil phosphoribosyltransferase [upp]. 9 217 40.5 T 31-10-2018 IPR034331 Uracil phosphoribosyltransferase, archaea GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 TK1287 06727e345df7aa32429971c12ecae337 230 SUPERFAMILY SSF53271 13 217 1.97E-56 T 31-10-2018 IPR029057 Phosphoribosyltransferase-like TK1656 91c935bd86c658291154ff88f8a4472d 328 Pfam PF00710 Asparaginase, N-terminal 2 187 3.3E-59 T 31-10-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 TK1656 91c935bd86c658291154ff88f8a4472d 328 Gene3D G3DSA:3.40.50.40 201 327 5.5E-43 T 31-10-2018 IPR027473 L-asparaginase, C-terminal Reactome: R-HSA-70614 TK1656 91c935bd86c658291154ff88f8a4472d 328 SMART SM00870 2 314 1.4E-123 T 31-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 TK1656 91c935bd86c658291154ff88f8a4472d 328 ProSitePatterns PS00917 Asparaginase / glutaminase active site signature 2. 78 88 - T 31-10-2018 IPR027475 Asparaginase/glutaminase, active site 2 Reactome: R-HSA-70614 TK1656 91c935bd86c658291154ff88f8a4472d 328 PIRSF PIRSF001220 1 325 1.9E-94 T 31-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 TK1656 91c935bd86c658291154ff88f8a4472d 328 ProSitePatterns PS00144 Asparaginase / glutaminase active site signature 1. 5 13 - T 31-10-2018 IPR020827 Asparaginase/glutaminase, active site 1 GO:0006520 TK1656 91c935bd86c658291154ff88f8a4472d 328 PRINTS PR00139 Asparaginase/glutaminase family signature 251 269 8.6E-14 T 31-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 TK1656 91c935bd86c658291154ff88f8a4472d 328 PRINTS PR00139 Asparaginase/glutaminase family signature 77 95 8.6E-14 T 31-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 TK1656 91c935bd86c658291154ff88f8a4472d 328 PRINTS PR00139 Asparaginase/glutaminase family signature 3 14 8.6E-14 T 31-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 TK1656 91c935bd86c658291154ff88f8a4472d 328 Gene3D G3DSA:3.40.50.1170 1 197 1.2E-68 T 31-10-2018 IPR037152 L-asparaginase, N-terminal domain superfamily Reactome: R-HSA-70614 TK1656 91c935bd86c658291154ff88f8a4472d 328 SUPERFAMILY SSF53774 2 326 9.55E-98 T 31-10-2018 IPR036152 Asparaginase/glutaminase-like superfamily Reactome: R-HSA-70614 TK1656 91c935bd86c658291154ff88f8a4472d 328 TIGRFAM TIGR00519 asnASE_I: L-asparaginase, type I 2 326 8.1E-92 T 31-10-2018 IPR006033 L-asparaginase, type I GO:0004067|GO:0006520 Reactome: R-HSA-70614 TK1656 91c935bd86c658291154ff88f8a4472d 328 PIRSF PIRSF500176 1 323 3.7E-98 T 31-10-2018 TK2240 3b2123242ec2dcbcafe106f487500de7 526 Gene3D G3DSA:1.10.10.860 271 318 5.8E-23 T 31-10-2018 TK2240 3b2123242ec2dcbcafe106f487500de7 526 SUPERFAMILY SSF52374 3 319 2.95E-68 T 31-10-2018 TK2240 3b2123242ec2dcbcafe106f487500de7 526 Gene3D G3DSA:1.10.10.770 319 433 2.7E-39 T 31-10-2018 TK2240 3b2123242ec2dcbcafe106f487500de7 526 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 30 39 - T 31-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 TK2240 3b2123242ec2dcbcafe106f487500de7 526 Hamap MF_00177 Lysine--tRNA ligase [lysS]. 2 526 38.072 T 31-10-2018 IPR002904 Lysine-tRNA ligase GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 TK2240 3b2123242ec2dcbcafe106f487500de7 526 Gene3D G3DSA:2.30.30.300 170 213 6.4E-110 T 31-10-2018 IPR023386 Lysine-tRNA ligase, insertion domain superfamily GO:0004824 KEGG: 00970+6.1.1.6 TK2240 3b2123242ec2dcbcafe106f487500de7 526 Gene3D G3DSA:3.40.50.620 4 270 6.4E-110 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TK2240 3b2123242ec2dcbcafe106f487500de7 526 TIGRFAM TIGR00467 lysS_arch: lysine--tRNA ligase 2 523 3.5E-160 T 31-10-2018 IPR002904 Lysine-tRNA ligase GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 TK2240 3b2123242ec2dcbcafe106f487500de7 526 Pfam PF01921 tRNA synthetases class I (K) 3 362 2.5E-139 T 31-10-2018 IPR002904 Lysine-tRNA ligase GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 TK2240 3b2123242ec2dcbcafe106f487500de7 526 Gene3D G3DSA:1.10.10.350 434 526 1.4E-25 T 31-10-2018 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 TK2240 3b2123242ec2dcbcafe106f487500de7 526 SUPERFAMILY SSF48163 323 523 4.19E-50 T 31-10-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 TK1978 4a512e7898ee5879ede7d2ac085a0846 185 TIGRFAM TIGR02175 PorC_KorC: 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate family 1 180 4.6E-80 T 31-10-2018 IPR011894 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate GO:0016625|GO:0055114 TK1978 4a512e7898ee5879ede7d2ac085a0846 185 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 10 177 2.7E-44 T 31-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 TK1978 4a512e7898ee5879ede7d2ac085a0846 185 SUPERFAMILY SSF53323 1 179 6.8E-58 T 31-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 TK1978 4a512e7898ee5879ede7d2ac085a0846 185 Gene3D G3DSA:3.40.920.10 1 182 9.6E-74 T 31-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 TK1687 05e59e0ea9543bf3abfa3448d3d6a633 273 Gene3D G3DSA:3.40.50.1100 3 262 3.7E-68 T 31-10-2018 TK1687 05e59e0ea9543bf3abfa3448d3d6a633 273 SUPERFAMILY SSF53686 3 269 2.62E-63 T 31-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme TK1687 05e59e0ea9543bf3abfa3448d3d6a633 273 Gene3D G3DSA:3.40.50.1100 19 120 3.7E-68 T 31-10-2018 TK1687 05e59e0ea9543bf3abfa3448d3d6a633 273 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 3 249 5.4E-48 T 31-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme TK2248 b6815d63e478d403d1e82954f0b3fbaf 312 SUPERFAMILY SSF102114 17 285 3.53E-41 T 31-10-2018 TK2248 b6815d63e478d403d1e82954f0b3fbaf 312 SMART SM00729 26 239 4.6E-24 T 31-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TK2248 b6815d63e478d403d1e82954f0b3fbaf 312 Gene3D G3DSA:3.20.20.70 18 239 8.7E-27 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TK2248 b6815d63e478d403d1e82954f0b3fbaf 312 Pfam PF04055 Radical SAM superfamily 38 193 4.6E-12 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TK0545 7dbc3c8b6dd18543ada42df751e81be5 405 Gene3D G3DSA:3.30.300.280 16 398 2.0E-172 T 31-10-2018 TK0545 7dbc3c8b6dd18543ada42df751e81be5 405 Gene3D G3DSA:3.30.300.10 30 154 2.0E-172 T 31-10-2018 TK0545 7dbc3c8b6dd18543ada42df751e81be5 405 Pfam PF01941 S-adenosylmethionine synthetase (AdoMet synthetase) 6 401 2.3E-179 T 31-10-2018 IPR027790 S-adenosylmethionine synthase KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912 TK0545 7dbc3c8b6dd18543ada42df751e81be5 405 Hamap MF_00136 S-adenosylmethionine synthase [mat]. 5 405 51.939 T 31-10-2018 IPR002795 S-adenosylmethionine synthetase, archaea GO:0004478|GO:0005524|GO:0006730 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912 TK0545 7dbc3c8b6dd18543ada42df751e81be5 405 ProDom PD011777 SYNTHETASE TRANSFERASE METHIONINE ADENOSYLTRANSFERASE S-ADENOSYLMETHIONINE NUCLEOTIDE-BINDING METABOLISM ATP-BINDING MAGNESIUM ONE-CARBON 21 405 0.0 T 31-10-2018 TK0545 7dbc3c8b6dd18543ada42df751e81be5 405 Gene3D G3DSA:3.30.300.340 18 286 2.0E-172 T 31-10-2018 TK0330 5c73bff1debedd822ffc4a93f7851acf 132 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 115 1.7E-24 T 31-10-2018 TK0330 5c73bff1debedd822ffc4a93f7851acf 132 Gene3D G3DSA:3.10.180.10 1 131 4.2E-43 T 31-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TK0330 5c73bff1debedd822ffc4a93f7851acf 132 TIGRFAM TIGR03081 metmalonyl_epim: methylmalonyl-CoA epimerase 4 130 1.5E-53 T 31-10-2018 IPR017515 Methylmalonyl-CoA epimerase KEGG: 00280+5.1.99.1|KEGG: 00630+5.1.99.1|KEGG: 00640+5.1.99.1|KEGG: 00720+5.1.99.1|MetaCyc: PWY-5741|MetaCyc: PWY-5743|MetaCyc: PWY-5789|MetaCyc: PWY-6728|MetaCyc: PWY-7384|MetaCyc: PWY-7854|Reactome: R-HSA-71032 TK0330 5c73bff1debedd822ffc4a93f7851acf 132 SUPERFAMILY SSF54593 1 131 1.11E-34 T 31-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TK2304 80dae3fccfd382d50ac6891a5f4ef25b 450 Pfam PF01029 NusB family 10 133 2.3E-19 T 31-10-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 TK2304 80dae3fccfd382d50ac6891a5f4ef25b 450 SUPERFAMILY SSF48013 9 163 1.44E-24 T 31-10-2018 IPR035926 NusB-like superfamily TK2304 80dae3fccfd382d50ac6891a5f4ef25b 450 SUPERFAMILY SSF53335 147 450 7.9E-71 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TK2304 80dae3fccfd382d50ac6891a5f4ef25b 450 Pfam PF01189 16S rRNA methyltransferase RsmB/F 255 449 1.5E-48 T 31-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 TK2304 80dae3fccfd382d50ac6891a5f4ef25b 450 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 381 397 2.7E-21 T 31-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TK2304 80dae3fccfd382d50ac6891a5f4ef25b 450 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 266 276 2.7E-21 T 31-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TK2304 80dae3fccfd382d50ac6891a5f4ef25b 450 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 433 450 2.7E-21 T 31-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TK2304 80dae3fccfd382d50ac6891a5f4ef25b 450 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 331 343 2.7E-21 T 31-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TK2304 80dae3fccfd382d50ac6891a5f4ef25b 450 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 237 251 2.7E-21 T 31-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TK2304 80dae3fccfd382d50ac6891a5f4ef25b 450 Gene3D G3DSA:1.10.940.10 6 150 3.1E-15 T 31-10-2018 IPR035926 NusB-like superfamily TK2304 80dae3fccfd382d50ac6891a5f4ef25b 450 Gene3D G3DSA:3.40.50.150 154 450 1.3E-77 T 31-10-2018 TK2243 e9a2d83ae277c5462787f035f6356fa5 383 Gene3D G3DSA:3.30.420.40 148 313 2.5E-7 T 31-10-2018 TK2243 e9a2d83ae277c5462787f035f6356fa5 383 Pfam PF07318 Protein of unknown function (DUF1464) 6 369 3.6E-100 T 31-10-2018 IPR009927 Protein of unknown function DUF1464 TK2243 e9a2d83ae277c5462787f035f6356fa5 383 SUPERFAMILY SSF53067 4 306 2.39E-12 T 31-10-2018 TK2243 e9a2d83ae277c5462787f035f6356fa5 383 PIRSF PIRSF009433 1 380 6.2E-162 T 31-10-2018 IPR009927 Protein of unknown function DUF1464 TK0470 e977dc67396d5c33b578f1414b3a72e0 1711 Gene3D G3DSA:1.10.290.10 1424 1542 9.9E-60 T 31-10-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 TK0470 e977dc67396d5c33b578f1414b3a72e0 1711 Gene3D G3DSA:2.170.16.10 958 1107 3.3E-15 T 31-10-2018 TK0470 e977dc67396d5c33b578f1414b3a72e0 1711 Pfam PF01131 DNA topoisomerase 1448 1698 1.2E-50 T 31-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 TK0470 e977dc67396d5c33b578f1414b3a72e0 1711 Pfam PF01131 DNA topoisomerase 820 960 2.6E-24 T 31-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 TK0470 e977dc67396d5c33b578f1414b3a72e0 1711 TIGRFAM TIGR01445 intein_Nterm: intein N-terminal splicing region 961 1035 1.1E-13 T 31-10-2018 IPR006141 Intein N-terminal splicing region GO:0016539 Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TK0470 e977dc67396d5c33b578f1414b3a72e0 1711 SUPERFAMILY SSF55608 1233 1316 3.4E-12 T 31-10-2018 IPR027434 Homing endonuclease TK0470 e977dc67396d5c33b578f1414b3a72e0 1711 SUPERFAMILY SSF52540 326 625 3.09E-38 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK0470 e977dc67396d5c33b578f1414b3a72e0 1711 SMART SM00493 642 795 1.7E-43 T 31-10-2018 IPR006171 TOPRIM domain TK0470 e977dc67396d5c33b578f1414b3a72e0 1711 SMART SM00437 916 1661 4.6E-97 T 31-10-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 TK0470 e977dc67396d5c33b578f1414b3a72e0 1711 Pfam PF01751 Toprim domain 644 805 4.0E-27 T 31-10-2018 IPR006171 TOPRIM domain TK0470 e977dc67396d5c33b578f1414b3a72e0 1711 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 1430 1450 0.0016 T 31-10-2018 IPR030934 Intein C-terminal splicing region TK0470 e977dc67396d5c33b578f1414b3a72e0 1711 Gene3D G3DSA:1.10.460.10 1606 1693 9.9E-60 T 31-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 TK0470 e977dc67396d5c33b578f1414b3a72e0 1711 SMART SM00436 796 883 1.9E-42 T 31-10-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 TK0470 e977dc67396d5c33b578f1414b3a72e0 1711 Pfam PF14528 LAGLIDADG-like domain 1240 1316 2.0E-10 T 31-10-2018 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 TK0470 e977dc67396d5c33b578f1414b3a72e0 1711 Gene3D G3DSA:3.10.28.10 1153 1314 9.3E-13 T 31-10-2018 IPR027434 Homing endonuclease TK0470 e977dc67396d5c33b578f1414b3a72e0 1711 SUPERFAMILY SSF56712 638 961 8.76E-76 T 31-10-2018 IPR023405 DNA topoisomerase, type IA, core domain TK0470 e977dc67396d5c33b578f1414b3a72e0 1711 Pfam PF00270 DEAD/DEAH box helicase 88 223 1.9E-11 T 31-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 TK0470 e977dc67396d5c33b578f1414b3a72e0 1711 Hamap MF_01125 Reverse gyrase [rgy]. 1 1709 58.536 T 31-10-2018 IPR005736 Reverse gyrase GO:0003677|GO:0003916|GO:0006265 TK0470 e977dc67396d5c33b578f1414b3a72e0 1711 TIGRFAM TIGR01054 rgy: reverse gyrase 2 1706 0.0 T 31-10-2018 IPR005736 Reverse gyrase GO:0003677|GO:0003916|GO:0006265 TK0470 e977dc67396d5c33b578f1414b3a72e0 1711 SMART SM00487 81 331 1.0E-22 T 31-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TK0470 e977dc67396d5c33b578f1414b3a72e0 1711 SMART SM00306 959 1059 5.9E-26 T 31-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TK0470 e977dc67396d5c33b578f1414b3a72e0 1711 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 855 873 2.6E-25 T 31-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 TK0470 e977dc67396d5c33b578f1414b3a72e0 1711 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 769 782 2.6E-25 T 31-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 TK0470 e977dc67396d5c33b578f1414b3a72e0 1711 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 1528 1544 2.6E-25 T 31-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 TK0470 e977dc67396d5c33b578f1414b3a72e0 1711 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 1622 1636 2.6E-25 T 31-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 TK0470 e977dc67396d5c33b578f1414b3a72e0 1711 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 1447 1456 2.6E-25 T 31-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 TK0470 e977dc67396d5c33b578f1414b3a72e0 1711 Gene3D G3DSA:3.40.50.300 320 502 3.8E-34 T 31-10-2018 TK0470 e977dc67396d5c33b578f1414b3a72e0 1711 Gene3D G3DSA:3.40.50.300 545 629 3.1E-14 T 31-10-2018 TK0470 e977dc67396d5c33b578f1414b3a72e0 1711 SUPERFAMILY SSF56712 1418 1708 8.76E-60 T 31-10-2018 IPR023405 DNA topoisomerase, type IA, core domain TK0470 e977dc67396d5c33b578f1414b3a72e0 1711 Gene3D G3DSA:3.40.50.140 640 824 1.3E-29 T 31-10-2018 TK0470 e977dc67396d5c33b578f1414b3a72e0 1711 SMART SM00305 1410 1455 2.4E-9 T 31-10-2018 IPR003586 Hint domain C-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TK0470 e977dc67396d5c33b578f1414b3a72e0 1711 Pfam PF14890 Intein splicing domain 968 1449 5.0E-37 T 31-10-2018 TK0470 e977dc67396d5c33b578f1414b3a72e0 1711 SUPERFAMILY SSF51294 961 1449 5.89E-28 T 31-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TK0470 e977dc67396d5c33b578f1414b3a72e0 1711 Gene3D G3DSA:1.10.460.10 825 890 8.3E-21 T 31-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 TK0470 e977dc67396d5c33b578f1414b3a72e0 1711 SUPERFAMILY SSF52540 3 240 4.01E-35 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK0470 e977dc67396d5c33b578f1414b3a72e0 1711 Gene3D G3DSA:2.70.20.10 1543 1605 9.9E-60 T 31-10-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 TK1399 cdce02203ed74d94394f69aee380770f 454 Gene3D G3DSA:1.20.1250.20 3 197 1.9E-29 T 31-10-2018 TK1399 cdce02203ed74d94394f69aee380770f 454 Pfam PF07690 Major Facilitator Superfamily 13 262 6.9E-33 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TK1399 cdce02203ed74d94394f69aee380770f 454 Pfam PF07690 Major Facilitator Superfamily 284 435 1.0E-16 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TK1399 cdce02203ed74d94394f69aee380770f 454 SUPERFAMILY SSF103473 9 437 3.27E-59 T 31-10-2018 IPR036259 MFS transporter superfamily TK1399 cdce02203ed74d94394f69aee380770f 454 Gene3D G3DSA:1.20.1250.20 223 440 1.5E-20 T 31-10-2018 TK1157 957ba35af0e30bab32da225760202636 796 Pfam PF09336 Vps4 C terminal oligomerisation domain 752 789 1.6E-4 T 31-10-2018 IPR015415 Vps4 oligomerisation, C-terminal TK1157 957ba35af0e30bab32da225760202636 796 ProSitePatterns PS00674 AAA-protein family signature. 319 337 - T 31-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 TK1157 957ba35af0e30bab32da225760202636 796 Pfam PF02933 Cell division protein 48 (CDC48), domain 2 107 169 1.0E-13 T 31-10-2018 IPR004201 CDC48, domain 2 TK1157 957ba35af0e30bab32da225760202636 796 SUPERFAMILY SSF54585 92 184 1.9E-20 T 31-10-2018 IPR029067 CDC48 domain 2-like superfamily TK1157 957ba35af0e30bab32da225760202636 796 SUPERFAMILY SSF52540 512 791 2.72E-81 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK1157 957ba35af0e30bab32da225760202636 796 SMART SM01073 8 92 3.7E-45 T 31-10-2018 IPR003338 CDC48, N-terminal subdomain TK1157 957ba35af0e30bab32da225760202636 796 TIGRFAM TIGR01243 CDC48: AAA family ATPase, CDC48 subfamily 7 794 0.0 T 31-10-2018 IPR005938 AAA ATPase, CDC48 family GO:0016787 Reactome: R-HSA-110320|Reactome: R-HSA-3371511|Reactome: R-HSA-382556|Reactome: R-HSA-532668|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5678895|Reactome: R-HSA-5689877|Reactome: R-HSA-5689896|Reactome: R-HSA-6798695|Reactome: R-HSA-8866654|Reactome: R-HSA-8876725 TK1157 957ba35af0e30bab32da225760202636 796 SUPERFAMILY SSF50692 2 90 1.55E-31 T 31-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily TK1157 957ba35af0e30bab32da225760202636 796 Gene3D G3DSA:2.40.40.20 1 92 1.2E-37 T 31-10-2018 TK1157 957ba35af0e30bab32da225760202636 796 Gene3D G3DSA:1.10.8.60 685 793 4.9E-34 T 31-10-2018 TK1157 957ba35af0e30bab32da225760202636 796 Gene3D G3DSA:1.10.8.60 430 512 1.3E-14 T 31-10-2018 TK1157 957ba35af0e30bab32da225760202636 796 SMART SM01072 107 170 3.4E-18 T 31-10-2018 IPR004201 CDC48, domain 2 TK1157 957ba35af0e30bab32da225760202636 796 Gene3D G3DSA:3.10.330.10 93 173 8.4E-8 T 31-10-2018 TK1157 957ba35af0e30bab32da225760202636 796 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 554 683 1.8E-49 T 31-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TK1157 957ba35af0e30bab32da225760202636 796 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 219 348 6.6E-52 T 31-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TK1157 957ba35af0e30bab32da225760202636 796 Gene3D G3DSA:1.10.8.60 350 417 1.5E-85 T 31-10-2018 TK1157 957ba35af0e30bab32da225760202636 796 Pfam PF02359 Cell division protein 48 (CDC48), N-terminal domain 8 91 3.3E-36 T 31-10-2018 IPR003338 CDC48, N-terminal subdomain TK1157 957ba35af0e30bab32da225760202636 796 ProSitePatterns PS00674 AAA-protein family signature. 654 672 - T 31-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 TK1157 957ba35af0e30bab32da225760202636 796 SMART SM00382 550 686 8.9E-25 T 31-10-2018 IPR003593 AAA+ ATPase domain TK1157 957ba35af0e30bab32da225760202636 796 SMART SM00382 215 351 4.2E-26 T 31-10-2018 IPR003593 AAA+ ATPase domain TK1157 957ba35af0e30bab32da225760202636 796 SUPERFAMILY SSF52540 179 502 5.1E-70 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK1157 957ba35af0e30bab32da225760202636 796 Gene3D G3DSA:3.40.50.300 513 683 4.4E-75 T 31-10-2018 TK1157 957ba35af0e30bab32da225760202636 796 Gene3D G3DSA:3.40.50.300 179 349 1.5E-85 T 31-10-2018 TK1506 520a85d04f767fded7534930e5d70d28 149 PIRSF PIRSF002134 1 149 2.2E-42 T 31-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1506 520a85d04f767fded7534930e5d70d28 149 ProSitePatterns PS00646 Ribosomal protein S13 signature. 117 130 - T 31-10-2018 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1506 520a85d04f767fded7534930e5d70d28 149 Gene3D G3DSA:4.10.910.10 88 138 3.1E-21 T 31-10-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1506 520a85d04f767fded7534930e5d70d28 149 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 8 148 25.559 T 31-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1506 520a85d04f767fded7534930e5d70d28 149 Gene3D G3DSA:1.10.8.50 1 76 1.5E-27 T 31-10-2018 TK1506 520a85d04f767fded7534930e5d70d28 149 SUPERFAMILY SSF46946 9 148 9.57E-36 T 31-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 TK1506 520a85d04f767fded7534930e5d70d28 149 TIGRFAM TIGR03629 uS13_arch: ribosomal protein uS13 4 148 9.9E-63 T 31-10-2018 IPR019977 Ribosomal protein S13, archaeal GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 TK1506 520a85d04f767fded7534930e5d70d28 149 Pfam PF00416 Ribosomal protein S13/S18 10 137 4.1E-42 T 31-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK0199 16adfdee55f2e462e0bfaddc9a2a1219 241 SUPERFAMILY SSF103473 15 238 1.83E-20 T 31-10-2018 IPR036259 MFS transporter superfamily TK0199 16adfdee55f2e462e0bfaddc9a2a1219 241 Pfam PF05977 Transmembrane secretion effector 20 235 2.0E-16 T 31-10-2018 IPR010290 Transmembrane secretion effector TK0199 16adfdee55f2e462e0bfaddc9a2a1219 241 Gene3D G3DSA:1.20.1250.20 15 241 4.6E-16 T 31-10-2018 TK0979 b93e6e3495e4841d9e0fb672bb29627c 254 Pfam PF01925 Sulfite exporter TauE/SafE 8 244 1.7E-61 T 31-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 TK2297 f5eb35da0238c59af5a45123b6b62944 341 SUPERFAMILY SSF48452 51 239 3.98E-23 T 31-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TK2297 f5eb35da0238c59af5a45123b6b62944 341 SMART SM00028 134 167 13.0 T 31-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TK2297 f5eb35da0238c59af5a45123b6b62944 341 SMART SM00028 211 244 69.0 T 31-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TK2297 f5eb35da0238c59af5a45123b6b62944 341 SMART SM00028 174 207 19.0 T 31-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TK2297 f5eb35da0238c59af5a45123b6b62944 341 SMART SM00028 93 126 0.0018 T 31-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TK2297 f5eb35da0238c59af5a45123b6b62944 341 SMART SM00028 55 88 19.0 T 31-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TK2297 f5eb35da0238c59af5a45123b6b62944 341 Gene3D G3DSA:1.25.40.10 125 334 5.7E-17 T 31-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TK2297 f5eb35da0238c59af5a45123b6b62944 341 Gene3D G3DSA:1.25.40.10 8 124 1.3E-11 T 31-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TK2297 f5eb35da0238c59af5a45123b6b62944 341 Pfam PF13424 Tetratricopeptide repeat 58 121 1.1E-8 T 31-10-2018 TK2297 f5eb35da0238c59af5a45123b6b62944 341 Pfam PF13424 Tetratricopeptide repeat 133 203 1.9E-10 T 31-10-2018 TK0566 1659233f8db8239c37fdb427113cbcb9 832 SUPERFAMILY SSF52540 227 552 4.73E-51 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK0566 1659233f8db8239c37fdb427113cbcb9 832 Gene3D G3DSA:3.40.50.300 404 626 6.2E-30 T 31-10-2018 TK0566 1659233f8db8239c37fdb427113cbcb9 832 SMART SM00487 213 410 2.1E-30 T 31-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TK0566 1659233f8db8239c37fdb427113cbcb9 832 Pfam PF00270 DEAD/DEAH box helicase 219 382 1.1E-24 T 31-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 TK0566 1659233f8db8239c37fdb427113cbcb9 832 SMART SM00490 453 538 3.1E-20 T 31-10-2018 IPR001650 Helicase, C-terminal TK0566 1659233f8db8239c37fdb427113cbcb9 832 Gene3D G3DSA:3.40.50.300 200 402 6.6E-51 T 31-10-2018 TK0566 1659233f8db8239c37fdb427113cbcb9 832 Pfam PF00271 Helicase conserved C-terminal domain 419 536 1.0E-13 T 31-10-2018 IPR001650 Helicase, C-terminal TK0430 735feb8c9b769bf12d07a293df33e0d2 198 Hamap MF_00705 IMP cyclohydrolase [purO]. 1 198 75.345 T 31-10-2018 IPR010191 IMP cyclohydrolase GO:0003937|GO:0006164|GO:0006188 KEGG: 00230+3.5.4.10|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 TK0430 735feb8c9b769bf12d07a293df33e0d2 198 Gene3D G3DSA:3.60.20.20 2 195 5.8E-58 T 31-10-2018 IPR036795 Inosine monophosphate cyclohydrolase-like superfamily GO:0003937|GO:0006164|GO:0006188 KEGG: 00230+3.5.4.10|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 TK0430 735feb8c9b769bf12d07a293df33e0d2 198 Pfam PF07826 IMP cyclohydrolase-like protein 3 187 4.8E-55 T 31-10-2018 IPR020600 Inosine monophosphate cyclohydrolase-like GO:0003937|GO:0006164|GO:0006188 KEGG: 00230+3.5.4.10|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 TK0430 735feb8c9b769bf12d07a293df33e0d2 198 PIRSF PIRSF004866 2 197 8.4E-84 T 31-10-2018 IPR010191 IMP cyclohydrolase GO:0003937|GO:0006164|GO:0006188 KEGG: 00230+3.5.4.10|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 TK0430 735feb8c9b769bf12d07a293df33e0d2 198 TIGRFAM TIGR01922 purO_arch: IMP cyclohydrolase 3 193 5.7E-52 T 31-10-2018 IPR010191 IMP cyclohydrolase GO:0003937|GO:0006164|GO:0006188 KEGG: 00230+3.5.4.10|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 TK0430 735feb8c9b769bf12d07a293df33e0d2 198 SUPERFAMILY SSF75569 2 195 1.44E-73 T 31-10-2018 IPR036795 Inosine monophosphate cyclohydrolase-like superfamily GO:0003937|GO:0006164|GO:0006188 KEGG: 00230+3.5.4.10|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 TK1116 b057afcf86bda06bee149ab29dcdb19a 421 Gene3D G3DSA:3.40.1350.30 114 262 3.8E-94 T 31-10-2018 TK1116 b057afcf86bda06bee149ab29dcdb19a 421 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 402 412 - T 31-10-2018 IPR030391 RNA methyltransferase TrmA, conserved site TK1116 b057afcf86bda06bee149ab29dcdb19a 421 Gene3D G3DSA:2.40.50.140 3 63 1.5E-11 T 31-10-2018 TK1116 b057afcf86bda06bee149ab29dcdb19a 421 SUPERFAMILY SSF53335 62 419 3.64E-66 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TK1116 b057afcf86bda06bee149ab29dcdb19a 421 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 10 412 5.2E-67 T 31-10-2018 TK1116 b057afcf86bda06bee149ab29dcdb19a 421 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 351 380 - T 31-10-2018 IPR030390 RNA methyltransferase TrmA, active site TK1116 b057afcf86bda06bee149ab29dcdb19a 421 SUPERFAMILY SSF50249 2 60 9.71E-7 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold TK1116 b057afcf86bda06bee149ab29dcdb19a 421 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 345 420 1.7E-13 T 31-10-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 TK1116 b057afcf86bda06bee149ab29dcdb19a 421 Gene3D G3DSA:3.40.50.150 75 414 3.8E-94 T 31-10-2018 TK1116 b057afcf86bda06bee149ab29dcdb19a 421 Pfam PF02475 Met-10+ like-protein 276 334 1.5E-8 T 31-10-2018 IPR030382 SAM-dependent methyltransferase TRM5/TYW2-type Reactome: R-HSA-6782861 TK1044 eef0c3a77d26cbc34b53929d43f08049 420 SUPERFAMILY SSF103473 4 396 2.75E-44 T 31-10-2018 IPR036259 MFS transporter superfamily TK1044 eef0c3a77d26cbc34b53929d43f08049 420 Pfam PF07690 Major Facilitator Superfamily 11 362 4.7E-34 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TK1044 eef0c3a77d26cbc34b53929d43f08049 420 PRINTS PR01988 Putative bacilysin exporter bacE signature 293 316 4.8E-10 T 31-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 TK1044 eef0c3a77d26cbc34b53929d43f08049 420 PRINTS PR01988 Putative bacilysin exporter bacE signature 46 64 4.8E-10 T 31-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 TK1044 eef0c3a77d26cbc34b53929d43f08049 420 PRINTS PR01988 Putative bacilysin exporter bacE signature 162 179 4.8E-10 T 31-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 TK1044 eef0c3a77d26cbc34b53929d43f08049 420 PRINTS PR01988 Putative bacilysin exporter bacE signature 72 90 4.8E-10 T 31-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 TK1044 eef0c3a77d26cbc34b53929d43f08049 420 PRINTS PR01988 Putative bacilysin exporter bacE signature 135 156 4.8E-10 T 31-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 TK1044 eef0c3a77d26cbc34b53929d43f08049 420 TIGRFAM TIGR00900 2A0121: H+ Antiporter protein 7 373 1.9E-104 T 31-10-2018 IPR004751 Drug antiporter protein GO:0015307|GO:0015893 TK1044 eef0c3a77d26cbc34b53929d43f08049 420 Gene3D G3DSA:1.20.1250.20 2 396 4.0E-41 T 31-10-2018 TK1626 21dc820d0752fcf494ab790a02028b43 280 Gene3D G3DSA:3.10.580.10 122 280 7.7E-36 T 31-10-2018 TK1626 21dc820d0752fcf494ab790a02028b43 280 SUPERFAMILY SSF54631 124 277 3.11E-31 T 31-10-2018 TK1626 21dc820d0752fcf494ab790a02028b43 280 SUPERFAMILY SSF54631 1 117 2.15E-29 T 31-10-2018 TK1626 21dc820d0752fcf494ab790a02028b43 280 SMART SM00116 10 58 3.3E-8 T 31-10-2018 IPR000644 CBS domain TK1626 21dc820d0752fcf494ab790a02028b43 280 SMART SM00116 69 117 7.2E-10 T 31-10-2018 IPR000644 CBS domain TK1626 21dc820d0752fcf494ab790a02028b43 280 SMART SM00116 230 278 1.3E-9 T 31-10-2018 IPR000644 CBS domain TK1626 21dc820d0752fcf494ab790a02028b43 280 SMART SM00116 135 183 2.8 T 31-10-2018 IPR000644 CBS domain TK1626 21dc820d0752fcf494ab790a02028b43 280 Pfam PF00571 CBS domain 3 54 2.6E-11 T 31-10-2018 IPR000644 CBS domain TK1626 21dc820d0752fcf494ab790a02028b43 280 Pfam PF00571 CBS domain 223 278 2.6E-12 T 31-10-2018 IPR000644 CBS domain TK1626 21dc820d0752fcf494ab790a02028b43 280 Pfam PF00571 CBS domain 67 115 2.6E-11 T 31-10-2018 IPR000644 CBS domain TK1626 21dc820d0752fcf494ab790a02028b43 280 Pfam PF00571 CBS domain 134 180 1.6E-5 T 31-10-2018 IPR000644 CBS domain TK1626 21dc820d0752fcf494ab790a02028b43 280 Gene3D G3DSA:3.10.580.10 1 121 7.7E-42 T 31-10-2018 TK1194 ca9c3c131a5eccf13f54c5af76b3fa64 131 Hamap MF_01223 UPF0212 protein . 1 112 32.362 T 31-10-2018 IPR007564 Uncharacterised protein family UPF0212 TK1194 ca9c3c131a5eccf13f54c5af76b3fa64 131 PIRSF PIRSF016934 1 125 5.3E-54 T 31-10-2018 IPR007564 Uncharacterised protein family UPF0212 TK1194 ca9c3c131a5eccf13f54c5af76b3fa64 131 ProDom PD020367 UPF0212 RRNAC1165 RRNAC0441 AF0282 VNG1264C MJ0068 PYRAB08340 PH1312 MA1372 TK1194 1 91 3.0E-47 T 31-10-2018 IPR007564 Uncharacterised protein family UPF0212 TK1194 ca9c3c131a5eccf13f54c5af76b3fa64 131 Pfam PF04475 Protein of unknown function (DUF555) 3 104 3.2E-40 T 31-10-2018 IPR007564 Uncharacterised protein family UPF0212 TK1836 081ac0eebc97a91695ebe7d01a613d91 371 Pfam PF01494 FAD binding domain 3 281 4.6E-15 T 31-10-2018 IPR002938 FAD-binding domain GO:0071949 TK1836 081ac0eebc97a91695ebe7d01a613d91 371 TIGRFAM TIGR02032 GG-red-SF: geranylgeranyl reductase family 3 273 2.6E-52 T 31-10-2018 IPR011777 Geranylgeranyl reductase family GO:0016628|GO:0055114 TK1836 081ac0eebc97a91695ebe7d01a613d91 371 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 134 149 3.6E-10 T 31-10-2018 TK1836 081ac0eebc97a91695ebe7d01a613d91 371 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 245 260 3.6E-10 T 31-10-2018 TK1836 081ac0eebc97a91695ebe7d01a613d91 371 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 3.6E-10 T 31-10-2018 TK1836 081ac0eebc97a91695ebe7d01a613d91 371 SUPERFAMILY SSF51905 2 284 1.02E-31 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TK1836 081ac0eebc97a91695ebe7d01a613d91 371 Gene3D G3DSA:3.50.50.60 1 369 1.3E-58 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TK2164 f8335da9fda911d3c3e8fd9e823b0909 375 SUPERFAMILY SSF111249 6 372 1.83E-179 T 31-10-2018 IPR036076 Fructose-1,6-bisphosphatase, class V superfamily KEGG: 00010+3.1.3.11+4.1.2.13|KEGG: 00030+3.1.3.11+4.1.2.13|KEGG: 00051+3.1.3.11+4.1.2.13|KEGG: 00680+3.1.3.11+4.1.2.13|KEGG: 00710+3.1.3.11+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 TK2164 f8335da9fda911d3c3e8fd9e823b0909 375 PIRSF PIRSF015647 5 375 5.7E-192 T 31-10-2018 IPR002803 Fructose-1,6-bisphosphatase, class V KEGG: 00010+4.1.2.13+3.1.3.11|KEGG: 00030+4.1.2.13+3.1.3.11|KEGG: 00051+4.1.2.13+3.1.3.11|KEGG: 00680+4.1.2.13+3.1.3.11|KEGG: 00710+4.1.2.13+3.1.3.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 TK2164 f8335da9fda911d3c3e8fd9e823b0909 375 Hamap MF_02067 Fructose-1,6-bisphosphate aldolase/phosphatase [fbp]. 5 372 62.507 T 31-10-2018 IPR002803 Fructose-1,6-bisphosphatase, class V KEGG: 00010+4.1.2.13+3.1.3.11|KEGG: 00030+4.1.2.13+3.1.3.11|KEGG: 00051+4.1.2.13+3.1.3.11|KEGG: 00680+4.1.2.13+3.1.3.11|KEGG: 00710+4.1.2.13+3.1.3.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 TK2164 f8335da9fda911d3c3e8fd9e823b0909 375 Pfam PF01950 Fructose-1,6-bisphosphatase 6 372 1.9E-187 T 31-10-2018 IPR002803 Fructose-1,6-bisphosphatase, class V KEGG: 00010+4.1.2.13+3.1.3.11|KEGG: 00030+4.1.2.13+3.1.3.11|KEGG: 00051+4.1.2.13+3.1.3.11|KEGG: 00680+4.1.2.13+3.1.3.11|KEGG: 00710+4.1.2.13+3.1.3.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 TK2164 f8335da9fda911d3c3e8fd9e823b0909 375 ProDom PD014260 DIHYDROOROTATE DEHYDROGENASE THERMOPHILE-SPECIFIC TA1428 ST0318 BLL2851 16-BISPHOSPHATASE APE1109 PF0613 MJ0299 6 371 0.0 T 31-10-2018 IPR002803 Fructose-1,6-bisphosphatase, class V KEGG: 00010+4.1.2.13+3.1.3.11|KEGG: 00030+4.1.2.13+3.1.3.11|KEGG: 00051+4.1.2.13+3.1.3.11|KEGG: 00680+4.1.2.13+3.1.3.11|KEGG: 00710+4.1.2.13+3.1.3.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 TK1558 42f0de2e5d8c7690ec9f7b5cfc835045 185 SMART SM00116 133 181 1.6E-9 T 31-10-2018 IPR000644 CBS domain TK1558 42f0de2e5d8c7690ec9f7b5cfc835045 185 SMART SM00116 55 102 7.5E-4 T 31-10-2018 IPR000644 CBS domain TK1558 42f0de2e5d8c7690ec9f7b5cfc835045 185 Pfam PF00571 CBS domain 126 180 4.5E-14 T 31-10-2018 IPR000644 CBS domain TK1558 42f0de2e5d8c7690ec9f7b5cfc835045 185 Pfam PF00571 CBS domain 51 101 5.4E-11 T 31-10-2018 IPR000644 CBS domain TK1558 42f0de2e5d8c7690ec9f7b5cfc835045 185 Gene3D G3DSA:3.10.580.10 2 107 3.7E-12 T 31-10-2018 TK1558 42f0de2e5d8c7690ec9f7b5cfc835045 185 Gene3D G3DSA:3.10.580.10 111 182 4.4E-16 T 31-10-2018 TK1558 42f0de2e5d8c7690ec9f7b5cfc835045 185 SUPERFAMILY SSF54631 36 180 2.29E-29 T 31-10-2018 TK0521 a59e8aabee641a5a786909a4588b0d38 900 Pfam PF09369 Domain of unknown function (DUF1998) 782 864 1.6E-15 T 31-10-2018 IPR018973 DEAD/DEAH-box helicase, putative TK0521 a59e8aabee641a5a786909a4588b0d38 900 SUPERFAMILY SSF52540 57 378 9.0E-48 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK0521 a59e8aabee641a5a786909a4588b0d38 900 SMART SM00487 44 251 4.9E-30 T 31-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TK0521 a59e8aabee641a5a786909a4588b0d38 900 Gene3D G3DSA:3.40.50.300 31 242 2.0E-40 T 31-10-2018 TK0521 a59e8aabee641a5a786909a4588b0d38 900 Pfam PF00271 Helicase conserved C-terminal domain 272 375 8.4E-18 T 31-10-2018 IPR001650 Helicase, C-terminal TK0521 a59e8aabee641a5a786909a4588b0d38 900 Pfam PF00270 DEAD/DEAH box helicase 50 227 5.6E-23 T 31-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 TK0521 a59e8aabee641a5a786909a4588b0d38 900 SMART SM00490 293 376 6.9E-19 T 31-10-2018 IPR001650 Helicase, C-terminal TK0521 a59e8aabee641a5a786909a4588b0d38 900 Gene3D G3DSA:3.40.50.300 254 407 4.3E-22 T 31-10-2018 TK2264 6d4c737557c6eed01e081ba6f2212858 716 Gene3D G3DSA:4.10.1080.10 116 234 6.0E-6 T 31-10-2018 IPR028974 TSP type-3 repeat GO:0005509 Reactome: R-HSA-186797 TK2264 6d4c737557c6eed01e081ba6f2212858 716 Gene3D G3DSA:4.10.1080.10 235 328 4.7E-5 T 31-10-2018 IPR028974 TSP type-3 repeat GO:0005509 Reactome: R-HSA-186797 TK2264 6d4c737557c6eed01e081ba6f2212858 716 ProSitePatterns PS00018 EF-hand calcium-binding domain. 195 207 - T 31-10-2018 IPR018247 EF-Hand 1, calcium-binding site TK2264 6d4c737557c6eed01e081ba6f2212858 716 Pfam PF04473 Transglutaminase-like domain 396 551 2.4E-57 T 31-10-2018 IPR007562 Transglutaminase-like domain TK2264 6d4c737557c6eed01e081ba6f2212858 716 Gene3D G3DSA:3.10.620.30 380 527 5.4E-7 T 31-10-2018 TK2264 6d4c737557c6eed01e081ba6f2212858 716 SUPERFAMILY SSF103647 54 141 6.28E-8 T 31-10-2018 IPR028974 TSP type-3 repeat GO:0005509 Reactome: R-HSA-186797 TK2264 6d4c737557c6eed01e081ba6f2212858 716 SUPERFAMILY SSF103647 118 251 5.23E-14 T 31-10-2018 IPR028974 TSP type-3 repeat GO:0005509 Reactome: R-HSA-186797 TK2264 6d4c737557c6eed01e081ba6f2212858 716 SUPERFAMILY SSF54001 383 515 4.9E-5 T 31-10-2018 IPR038765 Papain-like cysteine peptidase superfamily TK2264 6d4c737557c6eed01e081ba6f2212858 716 SUPERFAMILY SSF103647 234 370 6.41E-9 T 31-10-2018 IPR028974 TSP type-3 repeat GO:0005509 Reactome: R-HSA-186797 TK0814 8a86c30f69259a90915c6133fba13375 409 SMART SM00849 39 209 5.0E-27 T 31-10-2018 IPR001279 Metallo-beta-lactamase TK0814 8a86c30f69259a90915c6133fba13375 409 Gene3D G3DSA:3.60.15.10 1 258 1.7E-90 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TK0814 8a86c30f69259a90915c6133fba13375 409 PIRSF PIRSF005243 4 408 1.5E-116 T 31-10-2018 IPR016440 Rubredoxin-oxygen oxidoreductase GO:0009055|GO:0010181|GO:0016491|GO:0046872 TK0814 8a86c30f69259a90915c6133fba13375 409 SUPERFAMILY SSF52218 262 407 8.03E-31 T 31-10-2018 IPR029039 Flavoprotein-like superfamily TK0814 8a86c30f69259a90915c6133fba13375 409 Gene3D G3DSA:3.40.50.360 260 406 3.9E-29 T 31-10-2018 IPR029039 Flavoprotein-like superfamily TK0814 8a86c30f69259a90915c6133fba13375 409 SUPERFAMILY SSF56281 2 255 3.93E-45 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TK0814 8a86c30f69259a90915c6133fba13375 409 Pfam PF00753 Metallo-beta-lactamase superfamily 41 185 1.2E-6 T 31-10-2018 IPR001279 Metallo-beta-lactamase TK1878 58b9c22a7b40c66a5fe31291448960b5 258 SMART SM00849 36 225 1.1E-8 T 31-10-2018 IPR001279 Metallo-beta-lactamase TK1878 58b9c22a7b40c66a5fe31291448960b5 258 SUPERFAMILY SSF56281 1 258 9.83E-45 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TK1878 58b9c22a7b40c66a5fe31291448960b5 258 Pfam PF12706 Beta-lactamase superfamily domain 46 226 1.2E-23 T 31-10-2018 IPR001279 Metallo-beta-lactamase TK1878 58b9c22a7b40c66a5fe31291448960b5 258 Gene3D G3DSA:3.60.15.10 1 258 5.0E-50 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TK0800 ba28d654bce5272b735dcc6c6c3baa8d 238 SUPERFAMILY SSF54791 127 204 4.68E-18 T 31-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 TK0800 ba28d654bce5272b735dcc6c6c3baa8d 238 TIGRFAM TIGR03665 arCOG04150: arCOG04150 universal archaeal KH domain protein 41 214 8.7E-69 T 31-10-2018 IPR019964 KH domain protein, archaea TK0800 ba28d654bce5272b735dcc6c6c3baa8d 238 SUPERFAMILY SSF54791 39 114 3.14E-13 T 31-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 TK0800 ba28d654bce5272b735dcc6c6c3baa8d 238 Gene3D G3DSA:3.30.1370.10 35 117 5.2E-35 T 31-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 TK0800 ba28d654bce5272b735dcc6c6c3baa8d 238 Gene3D G3DSA:3.30.1370.10 118 223 4.6E-33 T 31-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 TK0800 ba28d654bce5272b735dcc6c6c3baa8d 238 Pfam PF00013 KH domain 142 189 3.7E-6 T 31-10-2018 IPR004088 K Homology domain, type 1 GO:0003723 TK0800 ba28d654bce5272b735dcc6c6c3baa8d 238 Pfam PF00013 KH domain 39 86 9.0E-10 T 31-10-2018 IPR004088 K Homology domain, type 1 GO:0003723 TK0800 ba28d654bce5272b735dcc6c6c3baa8d 238 SMART SM00322 35 105 1.2E-10 T 31-10-2018 IPR004087 K Homology domain GO:0003676 TK0800 ba28d654bce5272b735dcc6c6c3baa8d 238 SMART SM00322 126 193 8.9E-7 T 31-10-2018 IPR004087 K Homology domain GO:0003676 TK1318 d23a3dfa33eb4ac5de7992216e095030 197 PIRSF PIRSF035805 6 197 1.4E-66 T 31-10-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 TK1318 d23a3dfa33eb4ac5de7992216e095030 197 SUPERFAMILY SSF57716 147 195 6.65E-16 T 31-10-2018 TK1318 d23a3dfa33eb4ac5de7992216e095030 197 Hamap MF_00124 Thymidine kinase [tdk]. 7 195 36.097 T 31-10-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 TK1318 d23a3dfa33eb4ac5de7992216e095030 197 Pfam PF00265 Thymidine kinase 9 192 4.4E-52 T 31-10-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 TK1318 d23a3dfa33eb4ac5de7992216e095030 197 ProSitePatterns PS00603 Thymidine kinase cellular-type signature. 179 192 - T 31-10-2018 IPR020633 Thymidine kinase, conserved site GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 TK1318 d23a3dfa33eb4ac5de7992216e095030 197 Gene3D G3DSA:3.30.60.20 147 197 3.5E-24 T 31-10-2018 TK1318 d23a3dfa33eb4ac5de7992216e095030 197 SUPERFAMILY SSF52540 8 146 1.49E-38 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK1318 d23a3dfa33eb4ac5de7992216e095030 197 Gene3D G3DSA:3.40.50.300 2 146 4.6E-46 T 31-10-2018 TK1530 60a785a4e168304bfa0b655f554aed01 121 Gene3D G3DSA:2.30.30.30 2 121 3.6E-53 T 31-10-2018 IPR014722 Ribosomal protein L2, domain 2 TK1530 60a785a4e168304bfa0b655f554aed01 121 Hamap MF_01326_A 50S ribosomal protein L24 [rplX]. 5 118 32.489 T 31-10-2018 IPR005756 Ribosomal protein L26/L24, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1530 60a785a4e168304bfa0b655f554aed01 121 SUPERFAMILY SSF50104 6 115 2.84E-39 T 31-10-2018 IPR008991 Translation protein SH3-like domain superfamily TK1530 60a785a4e168304bfa0b655f554aed01 121 SMART SM00739 45 72 2.9E-6 T 31-10-2018 IPR005824 KOW TK1530 60a785a4e168304bfa0b655f554aed01 121 TIGRFAM TIGR01080 rplX_A_E: ribosomal protein uL24 6 120 1.6E-58 T 31-10-2018 IPR005756 Ribosomal protein L26/L24, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1530 60a785a4e168304bfa0b655f554aed01 121 ProSitePatterns PS01108 Ribosomal protein L24 signature. 49 66 - T 31-10-2018 IPR005825 Ribosomal protein L24/L26, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 TK1530 60a785a4e168304bfa0b655f554aed01 121 Pfam PF00467 KOW motif 48 79 7.1E-9 T 31-10-2018 IPR005824 KOW TK1530 60a785a4e168304bfa0b655f554aed01 121 Pfam PF16906 Ribosomal proteins L26 eukaryotic, L24P archaeal 6 119 8.6E-37 T 31-10-2018 IPR005756 Ribosomal protein L26/L24, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK2260 7d524c931a338e5bbef04d0dcbba5b56 302 Gene3D G3DSA:3.20.20.70 14 291 2.3E-94 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TK2260 7d524c931a338e5bbef04d0dcbba5b56 302 Hamap MF_00224 Dihydroorotate dehydrogenase [pyrD]. 6 300 36.961 T 31-10-2018 IPR024920 Dihydroorotate dehydrogenase, class 1 GO:0004152|GO:0005737|GO:0006221 TK2260 7d524c931a338e5bbef04d0dcbba5b56 302 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 237 257 - T 31-10-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 TK2260 7d524c931a338e5bbef04d0dcbba5b56 302 Pfam PF01180 Dihydroorotate dehydrogenase 6 285 4.0E-65 T 31-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 TK2260 7d524c931a338e5bbef04d0dcbba5b56 302 TIGRFAM TIGR01037 pyrD_sub1_fam: dihydroorotate dehydrogenase family protein 6 300 1.5E-130 T 31-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 TK2260 7d524c931a338e5bbef04d0dcbba5b56 302 ProSitePatterns PS00911 Dihydroorotate dehydrogenase signature 1. 42 61 - T 31-10-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 TK2260 7d524c931a338e5bbef04d0dcbba5b56 302 PIRSF PIRSF000164 1 302 2.3E-89 T 31-10-2018 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 TK2260 7d524c931a338e5bbef04d0dcbba5b56 302 SUPERFAMILY SSF51395 4 300 2.43E-84 T 31-10-2018 TK2260 7d524c931a338e5bbef04d0dcbba5b56 302 Gene3D G3DSA:2.30.26.10 57 214 2.3E-94 T 31-10-2018 IPR023359 Dihydroorotate dehydrogenase A, chain A, domain 2 TK0116 5a3cd93e63b57c44f10859bbdf62b5f5 492 SUPERFAMILY SSF51905 109 368 1.59E-22 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TK0116 5a3cd93e63b57c44f10859bbdf62b5f5 492 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 259 351 5.9E-8 T 31-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TK0116 5a3cd93e63b57c44f10859bbdf62b5f5 492 Gene3D G3DSA:3.10.20.440 1 95 1.3E-37 T 31-10-2018 TK0116 5a3cd93e63b57c44f10859bbdf62b5f5 492 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 110 255 8.3E-11 T 31-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TK0116 5a3cd93e63b57c44f10859bbdf62b5f5 492 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 206 224 4.8E-6 T 31-10-2018 TK0116 5a3cd93e63b57c44f10859bbdf62b5f5 492 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 111 130 4.8E-6 T 31-10-2018 TK0116 5a3cd93e63b57c44f10859bbdf62b5f5 492 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 300 316 4.8E-6 T 31-10-2018 TK0116 5a3cd93e63b57c44f10859bbdf62b5f5 492 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 13 88 5.0E-14 T 31-10-2018 TK0116 5a3cd93e63b57c44f10859bbdf62b5f5 492 Gene3D G3DSA:3.50.50.60 110 480 3.8E-155 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TK0116 5a3cd93e63b57c44f10859bbdf62b5f5 492 Gene3D G3DSA:1.10.10.1100 397 473 3.8E-155 T 31-10-2018 TK0116 5a3cd93e63b57c44f10859bbdf62b5f5 492 Gene3D G3DSA:3.50.50.60 218 308 3.8E-155 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TK1436 5b664a9cce6d7e86cfb5645e956602e6 675 Pfam PF09210 Domain of unknown function (DUF1957) 427 524 3.8E-28 T 31-10-2018 IPR015293 Domain of unknown function DUF1957 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900 TK1436 5b664a9cce6d7e86cfb5645e956602e6 675 SUPERFAMILY SSF47794 622 673 5.18E-9 T 31-10-2018 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 TK1436 5b664a9cce6d7e86cfb5645e956602e6 675 Pfam PF03065 Glycosyl hydrolase family 57 6 374 3.4E-75 T 31-10-2018 IPR004300 Glycoside hydrolase family 57, N-terminal domain GO:0003824|GO:0005975 TK1436 5b664a9cce6d7e86cfb5645e956602e6 675 Pfam PF14520 Helix-hairpin-helix domain 622 671 3.5E-11 T 31-10-2018 TK1436 5b664a9cce6d7e86cfb5645e956602e6 675 SUPERFAMILY SSF88688 416 532 1.6E-34 T 31-10-2018 IPR028995 Glycoside hydrolase families 57/38, central domain superfamily TK1436 5b664a9cce6d7e86cfb5645e956602e6 675 Gene3D G3DSA:1.10.150.20 621 675 1.3E-14 T 31-10-2018 TK1436 5b664a9cce6d7e86cfb5645e956602e6 675 SUPERFAMILY SSF88713 2 416 4.25E-125 T 31-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 TK1436 5b664a9cce6d7e86cfb5645e956602e6 675 Gene3D G3DSA:3.20.110.10 1 416 1.0E-184 T 31-10-2018 IPR027291 Glycoside hydrolase 38, N-terminal domain superfamily TK1436 5b664a9cce6d7e86cfb5645e956602e6 675 Gene3D G3DSA:1.20.1430.10 417 562 7.5E-70 T 31-10-2018 IPR037090 Glycoside hydrolase families 57, central domain KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900 TK1478 9ef867c79592997f95e1ca8991078f65 354 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 76 345 2.3E-60 T 31-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme TK1478 9ef867c79592997f95e1ca8991078f65 354 SUPERFAMILY SSF53686 2 352 1.19E-73 T 31-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme TK1478 9ef867c79592997f95e1ca8991078f65 354 Gene3D G3DSA:3.40.50.1100 46 349 5.7E-80 T 31-10-2018 TK1478 9ef867c79592997f95e1ca8991078f65 354 Gene3D G3DSA:3.40.50.1100 91 186 5.7E-80 T 31-10-2018 TK0615 03f0eff25471cafb64a11023b9ea4d03 86 TIGRFAM TIGR00280 eL43_euk_arch: ribosomal protein eL43 1 80 7.1E-37 T 31-10-2018 IPR002674 Ribosomal protein L37ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 TK0615 03f0eff25471cafb64a11023b9ea4d03 86 Gene3D G3DSA:2.20.25.30 9 86 1.8E-31 T 31-10-2018 IPR011331 Ribosomal protein L37ae/L37e GO:0003735|GO:0005622|GO:0005840|GO:0006412 TK0615 03f0eff25471cafb64a11023b9ea4d03 86 Hamap MF_00327 50S ribosomal protein L37Ae [rpl37ae]. 3 71 25.097 T 31-10-2018 IPR002674 Ribosomal protein L37ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 TK0615 03f0eff25471cafb64a11023b9ea4d03 86 SUPERFAMILY SSF57829 10 80 1.65E-28 T 31-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 TK0615 03f0eff25471cafb64a11023b9ea4d03 86 Pfam PF01780 Ribosomal L37ae protein family 3 82 1.7E-33 T 31-10-2018 IPR002674 Ribosomal protein L37ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 TK1997 b1d2dfd97af7ea85ca434050b04343b9 772 Gene3D G3DSA:3.90.870.50 6 362 1.4E-146 T 31-10-2018 TK1997 b1d2dfd97af7ea85ca434050b04343b9 772 Pfam PF00708 Acylphosphatase 4 88 2.1E-25 T 31-10-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 TK1997 b1d2dfd97af7ea85ca434050b04343b9 772 Pfam PF07503 HypF finger 158 191 2.2E-15 T 31-10-2018 IPR011125 Zinc finger, HypF-type GO:0008270 TK1997 b1d2dfd97af7ea85ca434050b04343b9 772 Pfam PF07503 HypF finger 108 141 1.3E-16 T 31-10-2018 IPR011125 Zinc finger, HypF-type GO:0008270 TK1997 b1d2dfd97af7ea85ca434050b04343b9 772 SUPERFAMILY SSF55821 175 390 3.97E-45 T 31-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily TK1997 b1d2dfd97af7ea85ca434050b04343b9 772 Gene3D G3DSA:3.30.420.360 383 755 1.2E-107 T 31-10-2018 TK1997 b1d2dfd97af7ea85ca434050b04343b9 772 PIRSF PIRSF006256 1 765 4.5E-288 T 31-10-2018 IPR004421 Carbamoyltransferase, HypF-type GO:0016743|GO:0046872|GO:0046944 TK1997 b1d2dfd97af7ea85ca434050b04343b9 772 TIGRFAM TIGR00143 hypF: carbamoyltransferase HypF 6 755 1.7E-268 T 31-10-2018 IPR004421 Carbamoyltransferase, HypF-type GO:0016743|GO:0046872|GO:0046944 TK1997 b1d2dfd97af7ea85ca434050b04343b9 772 SUPERFAMILY SSF53067 403 737 2.28E-7 T 31-10-2018 TK1997 b1d2dfd97af7ea85ca434050b04343b9 772 Pfam PF00814 Glycoprotease family 608 740 1.5E-6 T 31-10-2018 IPR000905 Gcp-like domain TK1997 b1d2dfd97af7ea85ca434050b04343b9 772 SUPERFAMILY SSF54975 1 88 1.57E-27 T 31-10-2018 IPR036046 Acylphosphatase-like domain superfamily KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 TK1997 b1d2dfd97af7ea85ca434050b04343b9 772 Gene3D G3DSA:3.30.110.120 252 371 1.4E-146 T 31-10-2018 TK1997 b1d2dfd97af7ea85ca434050b04343b9 772 Gene3D G3DSA:3.30.420.350 486 743 1.2E-107 T 31-10-2018 TK1997 b1d2dfd97af7ea85ca434050b04343b9 772 Pfam PF01300 Telomere recombination 208 383 2.0E-46 T 31-10-2018 IPR006070 YrdC-like domain GO:0003725 TK0304 dd129b3e24cfe48b3c2facc661c01fcf 439 SUPERFAMILY SSF51905 1 191 1.58E-48 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TK0304 dd129b3e24cfe48b3c2facc661c01fcf 439 SUPERFAMILY SSF51905 142 307 3.97E-34 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TK0304 dd129b3e24cfe48b3c2facc661c01fcf 439 SUPERFAMILY SSF55424 316 438 3.61E-27 T 31-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 TK0304 dd129b3e24cfe48b3c2facc661c01fcf 439 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 228 244 4.0E-23 T 31-10-2018 TK0304 dd129b3e24cfe48b3c2facc661c01fcf 439 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 3 22 4.0E-23 T 31-10-2018 TK0304 dd129b3e24cfe48b3c2facc661c01fcf 439 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 98 116 4.0E-23 T 31-10-2018 TK0304 dd129b3e24cfe48b3c2facc661c01fcf 439 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 145 163 4.0E-23 T 31-10-2018 TK0304 dd129b3e24cfe48b3c2facc661c01fcf 439 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 253 275 4.0E-23 T 31-10-2018 TK0304 dd129b3e24cfe48b3c2facc661c01fcf 439 Gene3D G3DSA:3.50.50.60 107 431 1.3E-146 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TK0304 dd129b3e24cfe48b3c2facc661c01fcf 439 Gene3D G3DSA:3.50.50.60 2 331 1.3E-146 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TK0304 dd129b3e24cfe48b3c2facc661c01fcf 439 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 2 24 6.5E-18 T 31-10-2018 TK0304 dd129b3e24cfe48b3c2facc661c01fcf 439 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 145 170 6.5E-18 T 31-10-2018 TK0304 dd129b3e24cfe48b3c2facc661c01fcf 439 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 268 275 6.5E-18 T 31-10-2018 TK0304 dd129b3e24cfe48b3c2facc661c01fcf 439 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 229 243 6.5E-18 T 31-10-2018 TK0304 dd129b3e24cfe48b3c2facc661c01fcf 439 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 296 5.9E-69 T 31-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TK0304 dd129b3e24cfe48b3c2facc661c01fcf 439 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 324 423 3.9E-16 T 31-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 TK2207 7d1b44836f64f6f146d0c35ea3a2eeef 199 Hamap MF_02113_A Proteasome subunit beta [prcB]. 2 198 34.849 T 31-10-2018 IPR019983 Peptidase T1A, proteasome beta-subunit, archaeal GO:0004175|GO:0005839|GO:0051603 TK2207 7d1b44836f64f6f146d0c35ea3a2eeef 199 PRINTS PR00141 Proteasome component signature 134 145 2.2E-5 T 31-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 TK2207 7d1b44836f64f6f146d0c35ea3a2eeef 199 PRINTS PR00141 Proteasome component signature 145 156 2.2E-5 T 31-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 TK2207 7d1b44836f64f6f146d0c35ea3a2eeef 199 PRINTS PR00141 Proteasome component signature 14 29 2.2E-5 T 31-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 TK2207 7d1b44836f64f6f146d0c35ea3a2eeef 199 Gene3D G3DSA:3.60.20.10 2 198 2.8E-62 T 31-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TK2207 7d1b44836f64f6f146d0c35ea3a2eeef 199 TIGRFAM TIGR03634 arc_protsome_B: proteasome endopeptidase complex, archaeal, beta subunit 6 190 1.3E-77 T 31-10-2018 IPR019983 Peptidase T1A, proteasome beta-subunit, archaeal GO:0004175|GO:0005839|GO:0051603 TK2207 7d1b44836f64f6f146d0c35ea3a2eeef 199 Pfam PF00227 Proteasome subunit 4 184 3.7E-52 T 31-10-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 TK2207 7d1b44836f64f6f146d0c35ea3a2eeef 199 SUPERFAMILY SSF56235 4 192 8.96E-59 T 31-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TK1774 5c75fcecb8f0b82cb6c7763cbf173fe7 1100 Gene3D G3DSA:2.60.40.1190 791 1033 2.4E-66 T 31-10-2018 TK1774 5c75fcecb8f0b82cb6c7763cbf173fe7 1100 SUPERFAMILY SSF88713 32 577 2.09E-65 T 31-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 TK1774 5c75fcecb8f0b82cb6c7763cbf173fe7 1100 Pfam PF09985 C-terminal binding-module, SLH-like, of glucodextranase 794 1027 1.9E-80 T 31-10-2018 IPR019248 Glucodextranase-like, C-terminal TK1774 5c75fcecb8f0b82cb6c7763cbf173fe7 1100 SUPERFAMILY SSF49344 793 1029 1.73E-80 T 31-10-2018 TK1774 5c75fcecb8f0b82cb6c7763cbf173fe7 1100 Gene3D G3DSA:3.20.110.20 219 574 2.1E-25 T 31-10-2018 TK1774 5c75fcecb8f0b82cb6c7763cbf173fe7 1100 Pfam PF03065 Glycosyl hydrolase family 57 36 538 3.0E-126 T 31-10-2018 IPR004300 Glycoside hydrolase family 57, N-terminal domain GO:0003824|GO:0005975 TK0634 60fd29816cb4f2e07b55a2ac3cb358f9 548 Gene3D G3DSA:3.30.70.1110 281 363 5.6E-8 T 31-10-2018 IPR037052 Chemotaxis protein CheA, P2 response regulator-binding domain superfamily TK0634 60fd29816cb4f2e07b55a2ac3cb358f9 548 Gene3D G3DSA:3.30.70.1110 171 254 1.2E-12 T 31-10-2018 IPR037052 Chemotaxis protein CheA, P2 response regulator-binding domain superfamily TK0634 60fd29816cb4f2e07b55a2ac3cb358f9 548 SUPERFAMILY SSF55874 466 531 1.86E-8 T 31-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TK0634 60fd29816cb4f2e07b55a2ac3cb358f9 548 Gene3D G3DSA:1.10.287.560 407 467 1.3E-19 T 31-10-2018 IPR037006 Histidine kinase CheA-like, homodimeric domain superfamily GO:0000155|GO:0006935 TK0634 60fd29816cb4f2e07b55a2ac3cb358f9 548 SMART SM00073 4 107 5.1E-24 T 31-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 TK0634 60fd29816cb4f2e07b55a2ac3cb358f9 548 Gene3D G3DSA:3.30.565.10 468 545 9.9E-18 T 31-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TK0634 60fd29816cb4f2e07b55a2ac3cb358f9 548 Pfam PF01627 Hpt domain 6 105 1.9E-21 T 31-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 TK0634 60fd29816cb4f2e07b55a2ac3cb358f9 548 SMART SM01231 407 467 2.8E-20 T 31-10-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 TK0634 60fd29816cb4f2e07b55a2ac3cb358f9 548 SUPERFAMILY SSF55052 172 253 5.23E-17 T 31-10-2018 IPR035891 CheY-binding domain of CheA TK0634 60fd29816cb4f2e07b55a2ac3cb358f9 548 SUPERFAMILY SSF55052 283 363 3.4E-14 T 31-10-2018 IPR035891 CheY-binding domain of CheA TK0634 60fd29816cb4f2e07b55a2ac3cb358f9 548 Pfam PF02895 Signal transducing histidine kinase, homodimeric domain 408 467 1.7E-16 T 31-10-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 TK0634 60fd29816cb4f2e07b55a2ac3cb358f9 548 Pfam PF07194 P2 response regulator binding domain 173 253 3.1E-18 T 31-10-2018 IPR010808 Chemotaxis protein CheA, P2 response regulator-binding GO:0000155|GO:0000160|GO:0004673|GO:0006928 TK0634 60fd29816cb4f2e07b55a2ac3cb358f9 548 Pfam PF07194 P2 response regulator binding domain 284 362 1.4E-13 T 31-10-2018 IPR010808 Chemotaxis protein CheA, P2 response regulator-binding GO:0000155|GO:0000160|GO:0004673|GO:0006928 TK0634 60fd29816cb4f2e07b55a2ac3cb358f9 548 Gene3D G3DSA:1.20.120.160 1 150 1.2E-33 T 31-10-2018 IPR036641 HPT domain superfamily GO:0000160 TK0634 60fd29816cb4f2e07b55a2ac3cb358f9 548 SUPERFAMILY SSF47226 3 134 8.24E-29 T 31-10-2018 IPR036641 HPT domain superfamily GO:0000160 TK0634 60fd29816cb4f2e07b55a2ac3cb358f9 548 SUPERFAMILY SSF47384 408 468 3.53E-16 T 31-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TK2087 0230cec103dafeb8097501f9795cea0a 514 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 75 123 2.2E-12 T 31-10-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TK2087 0230cec103dafeb8097501f9795cea0a 514 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 85 110 4.6E-16 T 31-10-2018 TK2087 0230cec103dafeb8097501f9795cea0a 514 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 320 332 4.6E-16 T 31-10-2018 TK2087 0230cec103dafeb8097501f9795cea0a 514 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 113 133 4.6E-16 T 31-10-2018 TK2087 0230cec103dafeb8097501f9795cea0a 514 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 225 246 4.6E-16 T 31-10-2018 TK2087 0230cec103dafeb8097501f9795cea0a 514 Pfam PF00361 Proton-conducting membrane transporter 137 437 5.9E-61 T 31-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TK0921 8e7b9ba1129ecb5402e6926205927725 501 Hamap MF_00282 Phenylalanine--tRNA ligase alpha subunit [pheS]. 2 498 38.179 T 31-10-2018 IPR022917 Phenylalanine-tRNA ligase alpha subunit, bacterial/archaeal GO:0004826 KEGG: 00970+6.1.1.20 TK0921 8e7b9ba1129ecb5402e6926205927725 501 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 184 497 9.0E-96 T 31-10-2018 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 TK0921 8e7b9ba1129ecb5402e6926205927725 501 Pfam PF01409 tRNA synthetases class II core domain (F) 224 496 6.6E-83 T 31-10-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 TK0921 8e7b9ba1129ecb5402e6926205927725 501 SUPERFAMILY SSF46785 2 110 3.46E-6 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TK0921 8e7b9ba1129ecb5402e6926205927725 501 SUPERFAMILY SSF55681 224 497 3.13E-60 T 31-10-2018 TK0921 8e7b9ba1129ecb5402e6926205927725 501 Gene3D G3DSA:3.30.930.10 193 500 9.0E-91 T 31-10-2018 TK0921 8e7b9ba1129ecb5402e6926205927725 501 Gene3D G3DSA:1.10.10.10 3 77 4.4E-5 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TK1503 5fb449df60a6b454a0a8dbfca4141795 259 Gene3D G3DSA:3.30.1360.10 5 250 2.6E-99 T 31-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TK1503 5fb449df60a6b454a0a8dbfca4141795 259 ProSitePatterns PS00446 RNA polymerases D / 30 to 40 Kd subunits signature. 27 67 - T 31-10-2018 IPR001514 DNA-directed RNA polymerase, 30-40kDa subunit, conserved site GO:0003677|GO:0003899|GO:0006351 TK1503 5fb449df60a6b454a0a8dbfca4141795 259 Gene3D G3DSA:2.170.120.12 39 146 2.6E-99 T 31-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TK1503 5fb449df60a6b454a0a8dbfca4141795 259 SUPERFAMILY SSF56553 38 148 1.96E-28 T 31-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TK1503 5fb449df60a6b454a0a8dbfca4141795 259 Hamap MF_00320 DNA-directed RNA polymerase subunit D [rpoD]. 2 256 32.955 T 31-10-2018 IPR022842 DNA-directed RNA polymerase subunit D (Rpo3) GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TK1503 5fb449df60a6b454a0a8dbfca4141795 259 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 45 147 1.5E-27 T 31-10-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TK1503 5fb449df60a6b454a0a8dbfca4141795 259 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 15 246 8.0E-19 T 31-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TK1503 5fb449df60a6b454a0a8dbfca4141795 259 Gene3D G3DSA:3.30.70.3110 156 217 2.6E-99 T 31-10-2018 TK1503 5fb449df60a6b454a0a8dbfca4141795 259 SUPERFAMILY SSF55257 3 256 7.46E-29 T 31-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TK1503 5fb449df60a6b454a0a8dbfca4141795 259 SMART SM00662 13 253 6.7E-84 T 31-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TK2010 64dc99f09ee6430794040a90e15f01ee 56 SUPERFAMILY SSF53146 2 47 1.03E-10 T 31-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily TK2010 64dc99f09ee6430794040a90e15f01ee 56 Gene3D G3DSA:3.30.420.130 1 54 2.6E-9 T 31-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily TK1115 8aa4825f509d56ca0776788093c21415 323 SMART SM00028 85 118 440.0 T 31-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TK1115 8aa4825f509d56ca0776788093c21415 323 SMART SM00028 125 158 0.0053 T 31-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TK1115 8aa4825f509d56ca0776788093c21415 323 SUPERFAMILY SSF48452 78 232 2.28E-11 T 31-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TK1115 8aa4825f509d56ca0776788093c21415 323 Gene3D G3DSA:1.25.40.10 5 232 1.3E-11 T 31-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TK0497 b7edb5c54eff0f55f4e5d0abc4f87941 331 Gene3D G3DSA:3.30.300.110 56 142 2.2E-29 T 31-10-2018 TK0497 b7edb5c54eff0f55f4e5d0abc4f87941 331 Gene3D G3DSA:3.40.50.150 143 331 1.6E-54 T 31-10-2018 TK0497 b7edb5c54eff0f55f4e5d0abc4f87941 331 Pfam PF02475 Met-10+ like-protein 82 277 8.7E-68 T 31-10-2018 IPR030382 SAM-dependent methyltransferase TRM5/TYW2-type Reactome: R-HSA-6782861 TK0497 b7edb5c54eff0f55f4e5d0abc4f87941 331 SUPERFAMILY SSF53335 72 330 8.81E-71 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TK0348 7f5b61e52313d6c4fa56ab3d975a2ea2 268 SMART SM00244 22 179 3.2E-70 T 31-10-2018 IPR001107 Band 7 domain TK0348 7f5b61e52313d6c4fa56ab3d975a2ea2 268 SUPERFAMILY SSF117892 53 186 2.75E-47 T 31-10-2018 IPR036013 Band 7/SPFH domain superfamily TK0348 7f5b61e52313d6c4fa56ab3d975a2ea2 268 PRINTS PR00721 Stomatin signature 199 222 1.1E-73 T 31-10-2018 IPR001972 Stomatin family GO:0016020 TK0348 7f5b61e52313d6c4fa56ab3d975a2ea2 268 PRINTS PR00721 Stomatin signature 111 128 1.1E-73 T 31-10-2018 IPR001972 Stomatin family GO:0016020 TK0348 7f5b61e52313d6c4fa56ab3d975a2ea2 268 PRINTS PR00721 Stomatin signature 174 195 1.1E-73 T 31-10-2018 IPR001972 Stomatin family GO:0016020 TK0348 7f5b61e52313d6c4fa56ab3d975a2ea2 268 PRINTS PR00721 Stomatin signature 29 51 1.1E-73 T 31-10-2018 IPR001972 Stomatin family GO:0016020 TK0348 7f5b61e52313d6c4fa56ab3d975a2ea2 268 PRINTS PR00721 Stomatin signature 131 154 1.1E-73 T 31-10-2018 IPR001972 Stomatin family GO:0016020 TK0348 7f5b61e52313d6c4fa56ab3d975a2ea2 268 PRINTS PR00721 Stomatin signature 155 173 1.1E-73 T 31-10-2018 IPR001972 Stomatin family GO:0016020 TK0348 7f5b61e52313d6c4fa56ab3d975a2ea2 268 PRINTS PR00721 Stomatin signature 76 97 1.1E-73 T 31-10-2018 IPR001972 Stomatin family GO:0016020 TK0348 7f5b61e52313d6c4fa56ab3d975a2ea2 268 Pfam PF01145 SPFH domain / Band 7 family 26 196 1.3E-39 T 31-10-2018 IPR001107 Band 7 domain TK0348 7f5b61e52313d6c4fa56ab3d975a2ea2 268 Gene3D G3DSA:3.30.479.30 50 181 2.1E-52 T 31-10-2018 TK2280 21b92d96bdf7169f0e24f4c4eb2c68fc 228 PIRSF PIRSF039123 1 227 5.9E-80 T 31-10-2018 IPR030662 Diphthine--ammonia ligase/Uncharacterised protein MJ0570 MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 TK2280 21b92d96bdf7169f0e24f4c4eb2c68fc 228 Pfam PF01902 Diphthamide synthase 1 209 3.0E-86 T 31-10-2018 IPR002761 Diphthamide synthase domain MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 TK2280 21b92d96bdf7169f0e24f4c4eb2c68fc 228 TIGRFAM TIGR00290 MJ0570_dom: MJ0570-related uncharacterized domain 1 218 5.6E-85 T 31-10-2018 IPR002761 Diphthamide synthase domain MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 TK2280 21b92d96bdf7169f0e24f4c4eb2c68fc 228 TIGRFAM TIGR03679 arCOG00187: arCOG00187 universal archaeal metal-binding-domain/4Fe-4S-binding-domain containing ABC transporter, ATP-binding protein 4 210 1.3E-87 T 31-10-2018 IPR022427 Uncharacterised protein MJ0570, ATP-binding TK2280 21b92d96bdf7169f0e24f4c4eb2c68fc 228 TIGRFAM TIGR00289 TIGR00289: TIGR00289 family protein 1 219 3.1E-91 T 31-10-2018 IPR005237 Uncharacterised protein MJ0570 TK2280 21b92d96bdf7169f0e24f4c4eb2c68fc 228 Gene3D G3DSA:3.90.1490.10 137 227 1.2E-31 T 31-10-2018 TK2280 21b92d96bdf7169f0e24f4c4eb2c68fc 228 SUPERFAMILY SSF52402 1 220 2.56E-74 T 31-10-2018 TK2280 21b92d96bdf7169f0e24f4c4eb2c68fc 228 Gene3D G3DSA:3.40.50.620 1 134 4.9E-48 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TK1057 4af2e750471b2db488481ecb41a7d725 82 Pfam PF01475 Ferric uptake regulator family 2 79 3.3E-10 T 31-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 TK1057 4af2e750471b2db488481ecb41a7d725 82 SUPERFAMILY SSF46785 2 69 2.22E-7 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TK1231 fb24aab64004716f54a15e131144699c 420 PIRSF PIRSF500136 1 417 3.5E-145 T 31-10-2018 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 TK1231 fb24aab64004716f54a15e131144699c 420 SUPERFAMILY SSF52413 304 405 1.57E-25 T 31-10-2018 IPR036220 UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily Reactome: R-HSA-173599 TK1231 fb24aab64004716f54a15e131144699c 420 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 314 405 2.7E-24 T 31-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 TK1231 fb24aab64004716f54a15e131144699c 420 Gene3D G3DSA:3.40.50.720 232 420 2.1E-68 T 31-10-2018 TK1231 fb24aab64004716f54a15e131144699c 420 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3 183 1.1E-52 T 31-10-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 TK1231 fb24aab64004716f54a15e131144699c 420 Gene3D G3DSA:3.40.50.720 3 198 1.4E-73 T 31-10-2018 TK1231 fb24aab64004716f54a15e131144699c 420 SUPERFAMILY SSF51735 2 193 1.53E-50 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily TK1231 fb24aab64004716f54a15e131144699c 420 SUPERFAMILY SSF48179 201 291 1.87E-27 T 31-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 TK1231 fb24aab64004716f54a15e131144699c 420 SMART SM00984 314 405 2.7E-36 T 31-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 TK1231 fb24aab64004716f54a15e131144699c 420 PIRSF PIRSF000124 2 408 4.0E-85 T 31-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 TK1231 fb24aab64004716f54a15e131144699c 420 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 201 287 5.1E-24 T 31-10-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 TK1231 fb24aab64004716f54a15e131144699c 420 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 3 400 6.2E-127 T 31-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 TK1240 67fd9ee247be3bb3d7396b9c61417e43 78 Pfam PF07441 SigmaK-factor processing regulatory protein BofA 7 77 2.6E-7 T 31-10-2018 IPR010001 SigmaK-factor processing regulatory BofA TK0969 1a685c6062bc67c6100fcd7c79a269b2 86 ProDom PD012670 RIBOSOMAL L35A 60S RIBONUCLEOPROTEIN L35A L35AE 50S RNA-BINDING TRNA-BINDING SEQUENCE 3 85 2.0E-41 T 31-10-2018 IPR001780 Ribosomal protein L35A GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK0969 1a685c6062bc67c6100fcd7c79a269b2 86 Gene3D G3DSA:2.40.10.190 1 86 1.1E-22 T 31-10-2018 IPR038661 Ribosomal protein L35A superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK0969 1a685c6062bc67c6100fcd7c79a269b2 86 Hamap MF_00573 50S ribosomal protein L35Ae [rpl35ae]. 2 86 22.868 T 31-10-2018 IPR001780 Ribosomal protein L35A GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK0969 1a685c6062bc67c6100fcd7c79a269b2 86 ProSitePatterns PS01105 Ribosomal protein L35Ae signature. 54 75 - T 31-10-2018 IPR018266 Ribosomal protein L35Ae, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK0969 1a685c6062bc67c6100fcd7c79a269b2 86 Pfam PF01247 Ribosomal protein L35Ae 3 85 4.2E-13 T 31-10-2018 IPR001780 Ribosomal protein L35A GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK0969 1a685c6062bc67c6100fcd7c79a269b2 86 SUPERFAMILY SSF50447 3 85 5.56E-23 T 31-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily TK1193 0d1739bf118571e6bd8bdeff92a2b30d 533 Pfam PF00117 Glutamine amidotransferase class-I 300 524 7.2E-58 T 31-10-2018 IPR017926 Glutamine amidotransferase TK1193 0d1739bf118571e6bd8bdeff92a2b30d 533 Pfam PF06418 CTP synthase N-terminus 3 265 1.9E-126 T 31-10-2018 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 TK1193 0d1739bf118571e6bd8bdeff92a2b30d 533 Hamap MF_01227 CTP synthase [pyrG]. 2 530 53.208 T 31-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 TK1193 0d1739bf118571e6bd8bdeff92a2b30d 533 TIGRFAM TIGR00337 PyrG: CTP synthase 1 525 2.7E-254 T 31-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 TK1193 0d1739bf118571e6bd8bdeff92a2b30d 533 Gene3D G3DSA:3.40.50.880 284 533 2.1E-109 T 31-10-2018 IPR029062 Class I glutamine amidotransferase-like TK1193 0d1739bf118571e6bd8bdeff92a2b30d 533 SUPERFAMILY SSF52540 2 265 8.77E-121 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK1193 0d1739bf118571e6bd8bdeff92a2b30d 533 Gene3D G3DSA:3.40.50.300 1 283 1.2E-138 T 31-10-2018 TK1193 0d1739bf118571e6bd8bdeff92a2b30d 533 SUPERFAMILY SSF52317 288 528 5.35E-80 T 31-10-2018 IPR029062 Class I glutamine amidotransferase-like TK1002 806b1e52fd796b24f9bd0f4c17ae81bc 339 Pfam PF00709 Adenylosuccinate synthetase 148 290 1.7E-44 T 31-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 TK1002 806b1e52fd796b24f9bd0f4c17ae81bc 339 Pfam PF00709 Adenylosuccinate synthetase 293 333 1.7E-5 T 31-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 TK1002 806b1e52fd796b24f9bd0f4c17ae81bc 339 SUPERFAMILY SSF52540 1 335 3.72E-108 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK1002 806b1e52fd796b24f9bd0f4c17ae81bc 339 SMART SM00788 3 334 2.6E-159 T 31-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 TK1002 806b1e52fd796b24f9bd0f4c17ae81bc 339 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 10 17 - T 31-10-2018 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 TK1002 806b1e52fd796b24f9bd0f4c17ae81bc 339 Gene3D G3DSA:3.40.440.10 1 339 2.4E-138 T 31-10-2018 TK1002 806b1e52fd796b24f9bd0f4c17ae81bc 339 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 339 99.167 T 31-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 TK1992 494eacd65c9a3521d83d00cc5c9412fd 386 Pfam PF07690 Major Facilitator Superfamily 16 342 1.5E-29 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TK1992 494eacd65c9a3521d83d00cc5c9412fd 386 SUPERFAMILY SSF103473 12 382 2.22E-51 T 31-10-2018 IPR036259 MFS transporter superfamily TK1992 494eacd65c9a3521d83d00cc5c9412fd 386 Gene3D G3DSA:1.20.1250.20 210 386 1.2E-17 T 31-10-2018 TK1992 494eacd65c9a3521d83d00cc5c9412fd 386 Gene3D G3DSA:1.20.1250.20 6 209 2.4E-26 T 31-10-2018 TK0447 004eb066af20807e0cd1f57e46a5892f 257 Pfam PF01881 CRISPR associated protein Cas6 107 256 4.8E-21 T 31-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 TK0447 004eb066af20807e0cd1f57e46a5892f 257 TIGRFAM TIGR01877 cas_cas6: CRISPR-associated endoribonuclease Cas6 62 255 9.8E-26 T 31-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 TK0447 004eb066af20807e0cd1f57e46a5892f 257 PIRSF PIRSF005054 1 257 7.9E-72 T 31-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 TK0447 004eb066af20807e0cd1f57e46a5892f 257 Gene3D G3DSA:3.30.70.1900 123 257 7.8E-26 T 31-10-2018 TK0447 004eb066af20807e0cd1f57e46a5892f 257 Gene3D G3DSA:3.30.70.1890 1 117 5.2E-11 T 31-10-2018 TK0131 d348c84bee6c18d0ca0072487da8b843 567 PIRSF PIRSF029056 1 567 5.7E-245 T 31-10-2018 IPR007548 Protein of unknown function DUF505 TK0131 d348c84bee6c18d0ca0072487da8b843 567 Pfam PF04458 Protein of unknown function (DUF505) 1 301 5.2E-81 T 31-10-2018 IPR007548 Protein of unknown function DUF505 TK0131 d348c84bee6c18d0ca0072487da8b843 567 Pfam PF04458 Protein of unknown function (DUF505) 306 566 1.5E-82 T 31-10-2018 IPR007548 Protein of unknown function DUF505 TK0308 485cd21b43d2d03f56a7d535e4c26dc5 428 SUPERFAMILY SSF50447 213 315 9.36E-29 T 31-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily TK0308 485cd21b43d2d03f56a7d535e4c26dc5 428 TIGRFAM TIGR00483 EF-1_alpha: translation elongation factor EF-1, subunit alpha 1 427 2.2E-214 T 31-10-2018 IPR004539 Translation elongation factor EF1A, eukaryotic/archaeal GO:0003746|GO:0005525|GO:0005737|GO:0006414 Reactome: R-HSA-156842 TK0308 485cd21b43d2d03f56a7d535e4c26dc5 428 Gene3D G3DSA:2.40.30.10 320 425 1.5E-40 T 31-10-2018 TK0308 485cd21b43d2d03f56a7d535e4c26dc5 428 SUPERFAMILY SSF52540 3 236 1.02E-76 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK0308 485cd21b43d2d03f56a7d535e4c26dc5 428 PRINTS PR00315 GTP-binding elongation factor signature 66 74 1.4E-24 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TK0308 485cd21b43d2d03f56a7d535e4c26dc5 428 PRINTS PR00315 GTP-binding elongation factor signature 102 113 1.4E-24 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TK0308 485cd21b43d2d03f56a7d535e4c26dc5 428 PRINTS PR00315 GTP-binding elongation factor signature 86 96 1.4E-24 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TK0308 485cd21b43d2d03f56a7d535e4c26dc5 428 PRINTS PR00315 GTP-binding elongation factor signature 9 22 1.4E-24 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TK0308 485cd21b43d2d03f56a7d535e4c26dc5 428 PRINTS PR00315 GTP-binding elongation factor signature 139 148 1.4E-24 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TK0308 485cd21b43d2d03f56a7d535e4c26dc5 428 SUPERFAMILY SSF50465 321 424 6.83E-39 T 31-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal TK0308 485cd21b43d2d03f56a7d535e4c26dc5 428 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 59 74 - T 31-10-2018 IPR031157 Tr-type G domain, conserved site TK0308 485cd21b43d2d03f56a7d535e4c26dc5 428 Gene3D G3DSA:3.40.50.300 1 212 4.3E-88 T 31-10-2018 TK0308 485cd21b43d2d03f56a7d535e4c26dc5 428 Pfam PF03144 Elongation factor Tu domain 2 235 306 3.6E-18 T 31-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 TK0308 485cd21b43d2d03f56a7d535e4c26dc5 428 Hamap MF_00118_A Elongation factor Tu [tuf]. 2 427 61.403 T 31-10-2018 IPR004539 Translation elongation factor EF1A, eukaryotic/archaeal GO:0003746|GO:0005525|GO:0005737|GO:0006414 Reactome: R-HSA-156842 TK0308 485cd21b43d2d03f56a7d535e4c26dc5 428 Gene3D G3DSA:2.40.30.10 216 310 1.5E-41 T 31-10-2018 TK0308 485cd21b43d2d03f56a7d535e4c26dc5 428 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 8 190 4.5E-17 T 31-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 TK0308 485cd21b43d2d03f56a7d535e4c26dc5 428 Pfam PF00009 Elongation factor Tu GTP binding domain 5 209 4.0E-60 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TK0308 485cd21b43d2d03f56a7d535e4c26dc5 428 Pfam PF03143 Elongation factor Tu C-terminal domain 317 424 4.3E-37 T 31-10-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal TK1284 e2a21a6eff5bdb57bc618e8f14748f33 166 Pfam PF01965 DJ-1/PfpI family 1 163 1.3E-59 T 31-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 TK1284 e2a21a6eff5bdb57bc618e8f14748f33 166 Gene3D G3DSA:3.40.50.880 1 166 2.3E-53 T 31-10-2018 IPR029062 Class I glutamine amidotransferase-like TK1284 e2a21a6eff5bdb57bc618e8f14748f33 166 SUPERFAMILY SSF52317 1 165 4.16E-53 T 31-10-2018 IPR029062 Class I glutamine amidotransferase-like TK1284 e2a21a6eff5bdb57bc618e8f14748f33 166 TIGRFAM TIGR01382 PfpI: intracellular protease, PfpI family 2 165 5.1E-68 T 31-10-2018 IPR006286 Deglycase PfpI TK1689 8f15dbcf23ed4b5073ff39b1f8980677 663 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 203 213 - T 31-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site TK1689 8f15dbcf23ed4b5073ff39b1f8980677 663 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 166 177 - T 31-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site TK1689 8f15dbcf23ed4b5073ff39b1f8980677 663 Gene3D G3DSA:3.30.70.80 39 131 7.6E-62 T 31-10-2018 IPR037045 Peptidase S8 propeptide/proteinase inhibitor I9 superfamily Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 TK1689 8f15dbcf23ed4b5073ff39b1f8980677 663 Pfam PF04151 Bacterial pre-peptidase C-terminal domain 578 645 7.5E-10 T 31-10-2018 IPR007280 Peptidase, C-terminal, archaeal/bacterial TK1689 8f15dbcf23ed4b5073ff39b1f8980677 663 Pfam PF04151 Bacterial pre-peptidase C-terminal domain 461 523 1.5E-5 T 31-10-2018 IPR007280 Peptidase, C-terminal, archaeal/bacterial TK1689 8f15dbcf23ed4b5073ff39b1f8980677 663 SUPERFAMILY SSF52743 151 441 6.55E-91 T 31-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 TK1689 8f15dbcf23ed4b5073ff39b1f8980677 663 Gene3D G3DSA:2.60.120.380 444 545 8.5E-26 T 31-10-2018 TK1689 8f15dbcf23ed4b5073ff39b1f8980677 663 Gene3D G3DSA:2.60.120.380 563 661 1.6E-16 T 31-10-2018 TK1689 8f15dbcf23ed4b5073ff39b1f8980677 663 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 380 390 - T 31-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site TK1689 8f15dbcf23ed4b5073ff39b1f8980677 663 Gene3D G3DSA:3.40.50.200 132 443 7.5E-144 T 31-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 TK1689 8f15dbcf23ed4b5073ff39b1f8980677 663 SUPERFAMILY SSF49785 452 527 4.0E-7 T 31-10-2018 IPR008979 Galactose-binding-like domain superfamily TK1689 8f15dbcf23ed4b5073ff39b1f8980677 663 PIRSF PIRSF037907 1 663 0.0 T 31-10-2018 IPR017319 Subtilisin-like serine protease TK1689-type TK1689 8f15dbcf23ed4b5073ff39b1f8980677 663 PRINTS PR00723 Subtilisin serine protease family (S8) signature 161 180 5.3E-22 T 31-10-2018 IPR015500 Peptidase S8, subtilisin-related TK1689 8f15dbcf23ed4b5073ff39b1f8980677 663 PRINTS PR00723 Subtilisin serine protease family (S8) signature 379 395 5.3E-22 T 31-10-2018 IPR015500 Peptidase S8, subtilisin-related TK1689 8f15dbcf23ed4b5073ff39b1f8980677 663 PRINTS PR00723 Subtilisin serine protease family (S8) signature 199 212 5.3E-22 T 31-10-2018 IPR015500 Peptidase S8, subtilisin-related TK1689 8f15dbcf23ed4b5073ff39b1f8980677 663 Pfam PF00082 Subtilase family 161 431 7.2E-66 T 31-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 TK2067 7d1c57ba875b8e5febcd03173056f1a4 143 SMART SM00670 2 131 1.0E-14 T 31-10-2018 IPR002716 PIN domain TK2067 7d1c57ba875b8e5febcd03173056f1a4 143 Gene3D G3DSA:3.40.50.1010 4 140 1.5E-13 T 31-10-2018 TK2067 7d1c57ba875b8e5febcd03173056f1a4 143 SUPERFAMILY SSF88723 1 131 9.81E-21 T 31-10-2018 IPR029060 PIN-like domain superfamily TK2067 7d1c57ba875b8e5febcd03173056f1a4 143 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 4 139 9.767 T 31-10-2018 IPR022907 VapC family GO:0004540 TK2067 7d1c57ba875b8e5febcd03173056f1a4 143 Pfam PF01850 PIN domain 5 132 9.0E-21 T 31-10-2018 IPR002716 PIN domain TK1853 0809a9c57371a8e2cd34def2ad0e071f 1198 Gene3D G3DSA:3.30.450.380 155 375 1.9E-65 T 31-10-2018 TK1853 0809a9c57371a8e2cd34def2ad0e071f 1198 Gene3D G3DSA:2.170.16.10 958 1033 1.4E-11 T 31-10-2018 TK1853 0809a9c57371a8e2cd34def2ad0e071f 1198 Gene3D G3DSA:2.170.16.10 514 655 8.4E-29 T 31-10-2018 TK1853 0809a9c57371a8e2cd34def2ad0e071f 1198 Gene3D G3DSA:3.40.50.300 1034 1186 1.4E-34 T 31-10-2018 TK1853 0809a9c57371a8e2cd34def2ad0e071f 1198 Gene3D G3DSA:3.40.50.300 376 513 1.8E-58 T 31-10-2018 TK1853 0809a9c57371a8e2cd34def2ad0e071f 1198 TIGRFAM TIGR01445 intein_Nterm: intein N-terminal splicing region 519 612 1.4E-9 T 31-10-2018 IPR006141 Intein N-terminal splicing region GO:0016539 Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TK1853 0809a9c57371a8e2cd34def2ad0e071f 1198 PRINTS PR00379 Intein signature 702 714 8.9E-18 T 31-10-2018 IPR006142 Intein GO:0016539 TK1853 0809a9c57371a8e2cd34def2ad0e071f 1198 PRINTS PR00379 Intein signature 800 812 8.9E-18 T 31-10-2018 IPR006142 Intein GO:0016539 TK1853 0809a9c57371a8e2cd34def2ad0e071f 1198 PRINTS PR00379 Intein signature 828 843 8.9E-18 T 31-10-2018 IPR006142 Intein GO:0016539 TK1853 0809a9c57371a8e2cd34def2ad0e071f 1198 PRINTS PR00379 Intein signature 599 612 8.9E-18 T 31-10-2018 IPR006142 Intein GO:0016539 TK1853 0809a9c57371a8e2cd34def2ad0e071f 1198 PRINTS PR00379 Intein signature 1011 1028 8.9E-18 T 31-10-2018 IPR006142 Intein GO:0016539 TK1853 0809a9c57371a8e2cd34def2ad0e071f 1198 Gene3D G3DSA:3.10.28.10 699 873 9.0E-24 T 31-10-2018 IPR027434 Homing endonuclease TK1853 0809a9c57371a8e2cd34def2ad0e071f 1198 Pfam PF14890 Intein splicing domain 532 1032 1.5E-27 T 31-10-2018 TK1853 0809a9c57371a8e2cd34def2ad0e071f 1198 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 1013 1035 2.2E-9 T 31-10-2018 IPR030934 Intein C-terminal splicing region TK1853 0809a9c57371a8e2cd34def2ad0e071f 1198 SMART SM00306 510 636 9.2E-21 T 31-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TK1853 0809a9c57371a8e2cd34def2ad0e071f 1198 SUPERFAMILY SSF55608 786 892 1.46E-21 T 31-10-2018 IPR027434 Homing endonuclease TK1853 0809a9c57371a8e2cd34def2ad0e071f 1198 SUPERFAMILY SSF52540 261 511 1.99E-46 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK1853 0809a9c57371a8e2cd34def2ad0e071f 1198 Pfam PF14528 LAGLIDADG-like domain 799 874 2.6E-14 T 31-10-2018 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 TK1853 0809a9c57371a8e2cd34def2ad0e071f 1198 Pfam PF00437 Type II/IV secretion system protein 281 513 7.9E-54 T 31-10-2018 IPR001482 Type II/IV secretion system protein TK1853 0809a9c57371a8e2cd34def2ad0e071f 1198 SUPERFAMILY SSF51294 517 1035 3.34E-36 T 31-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TK1853 0809a9c57371a8e2cd34def2ad0e071f 1198 SMART SM00305 990 1040 2.7E-15 T 31-10-2018 IPR003586 Hint domain C-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TK0759 a237f878055aca21c572c1a5bc76c029 431 Gene3D G3DSA:2.40.50.140 1 101 2.4E-29 T 31-10-2018 TK0759 a237f878055aca21c572c1a5bc76c029 431 SUPERFAMILY SSF50249 5 99 5.52E-25 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold TK0759 a237f878055aca21c572c1a5bc76c029 431 TIGRFAM TIGR00457 asnS: asparagine--tRNA ligase 14 430 5.4E-129 T 31-10-2018 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22 TK0759 a237f878055aca21c572c1a5bc76c029 431 PRINTS PR01042 Aspartyl-tRNA synthetase signature 197 210 9.8E-15 T 31-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 TK0759 a237f878055aca21c572c1a5bc76c029 431 PRINTS PR01042 Aspartyl-tRNA synthetase signature 386 400 9.8E-15 T 31-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 TK0759 a237f878055aca21c572c1a5bc76c029 431 PRINTS PR01042 Aspartyl-tRNA synthetase signature 346 362 9.8E-15 T 31-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 TK0759 a237f878055aca21c572c1a5bc76c029 431 PRINTS PR01042 Aspartyl-tRNA synthetase signature 181 193 9.8E-15 T 31-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 TK0759 a237f878055aca21c572c1a5bc76c029 431 Pfam PF01336 OB-fold nucleic acid binding domain 19 97 5.0E-15 T 31-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 TK0759 a237f878055aca21c572c1a5bc76c029 431 Hamap MF_00534 Asparagine--tRNA ligase [asnS]. 4 431 37.597 T 31-10-2018 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22 TK0759 a237f878055aca21c572c1a5bc76c029 431 Pfam PF00152 tRNA synthetases class II (D, K and N) 111 425 2.0E-87 T 31-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 TK0759 a237f878055aca21c572c1a5bc76c029 431 SUPERFAMILY SSF55681 111 426 1.08E-88 T 31-10-2018 TK0759 a237f878055aca21c572c1a5bc76c029 431 Gene3D G3DSA:3.30.930.10 105 431 1.1E-116 T 31-10-2018 TK0465 2fec5d041efccb678336c355d2298d4c 232 Pfam PF13549 ATP-grasp domain 16 231 6.2E-84 T 31-10-2018 TK0465 2fec5d041efccb678336c355d2298d4c 232 SUPERFAMILY SSF56059 23 232 4.42E-51 T 31-10-2018 TK0465 2fec5d041efccb678336c355d2298d4c 232 Gene3D G3DSA:3.30.470.20 21 230 1.6E-91 T 31-10-2018 TK0465 2fec5d041efccb678336c355d2298d4c 232 Gene3D G3DSA:3.30.1490.20 39 116 1.6E-91 T 31-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 TK2167 f6e77063b8a16d98efa22aab1331c8ec 435 Gene3D G3DSA:3.40.50.620 218 409 7.8E-37 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TK2167 f6e77063b8a16d98efa22aab1331c8ec 435 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 236 402 1.8E-36 T 31-10-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824 Reactome: R-HSA-196843 TK2167 f6e77063b8a16d98efa22aab1331c8ec 435 SUPERFAMILY SSF52402 216 391 2.65E-35 T 31-10-2018 TK0678 f5091a6b8d1897b0f6ca1857f5d9bf57 548 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 373 395 1.6E-34 T 31-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 TK0678 f5091a6b8d1897b0f6ca1857f5d9bf57 548 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 37 53 1.6E-34 T 31-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 TK0678 f5091a6b8d1897b0f6ca1857f5d9bf57 548 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 407 419 1.6E-34 T 31-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 TK0678 f5091a6b8d1897b0f6ca1857f5d9bf57 548 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 89 108 1.6E-34 T 31-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 TK0678 f5091a6b8d1897b0f6ca1857f5d9bf57 548 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 59 77 1.6E-34 T 31-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 TK0678 f5091a6b8d1897b0f6ca1857f5d9bf57 548 Gene3D G3DSA:1.10.560.10 28 522 2.4E-221 T 31-10-2018 IPR027413 GroEL-like equatorial domain superfamily TK0678 f5091a6b8d1897b0f6ca1857f5d9bf57 548 ProSitePatterns PS00750 Chaperonins TCP-1 signature 1. 40 52 - T 31-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 TK0678 f5091a6b8d1897b0f6ca1857f5d9bf57 548 SUPERFAMILY SSF54849 148 405 1.86E-30 T 31-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily TK0678 f5091a6b8d1897b0f6ca1857f5d9bf57 548 SUPERFAMILY SSF48592 17 524 1.01E-91 T 31-10-2018 IPR027413 GroEL-like equatorial domain superfamily TK0678 f5091a6b8d1897b0f6ca1857f5d9bf57 548 SUPERFAMILY SSF52029 212 378 9.84E-64 T 31-10-2018 IPR027409 GroEL-like apical domain superfamily TK0678 f5091a6b8d1897b0f6ca1857f5d9bf57 548 TIGRFAM TIGR02339 thermosome_arch: thermosome, various subunits, archaeal 8 525 2.4E-239 T 31-10-2018 IPR012714 Thermosome, archaeal GO:0005524|GO:0006457|GO:0051082 TK0678 f5091a6b8d1897b0f6ca1857f5d9bf57 548 Gene3D G3DSA:3.30.260.10 147 405 2.4E-221 T 31-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily TK0678 f5091a6b8d1897b0f6ca1857f5d9bf57 548 Gene3D G3DSA:3.50.7.10 218 369 2.4E-221 T 31-10-2018 IPR027409 GroEL-like apical domain superfamily TK0678 f5091a6b8d1897b0f6ca1857f5d9bf57 548 Pfam PF00118 TCP-1/cpn60 chaperonin family 35 525 1.8E-183 T 31-10-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 TK0678 f5091a6b8d1897b0f6ca1857f5d9bf57 548 ProSitePatterns PS00751 Chaperonins TCP-1 signature 2. 61 77 - T 31-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 TK0678 f5091a6b8d1897b0f6ca1857f5d9bf57 548 ProSitePatterns PS00995 Chaperonins TCP-1 signature 3. 89 97 - T 31-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 TK1492 b6bafaa2273768489898c31350fecd95 253 PIRSF PIRSF000883 2 252 3.0E-27 T 31-10-2018 IPR011152 Phosphoesterase MJ0912 TK1492 b6bafaa2273768489898c31350fecd95 253 Gene3D G3DSA:3.60.21.10 1 253 4.7E-51 T 31-10-2018 IPR029052 Metallo-dependent phosphatase-like TK1492 b6bafaa2273768489898c31350fecd95 253 SUPERFAMILY SSF56300 1 252 5.82E-59 T 31-10-2018 TK0712 e3c27e80eb8b64c2baed55e8291ab9b2 220 SMART SM00849 19 191 3.4E-7 T 31-10-2018 IPR001279 Metallo-beta-lactamase TK0712 e3c27e80eb8b64c2baed55e8291ab9b2 220 Pfam PF00753 Metallo-beta-lactamase superfamily 43 130 2.2E-7 T 31-10-2018 IPR001279 Metallo-beta-lactamase TK0712 e3c27e80eb8b64c2baed55e8291ab9b2 220 Gene3D G3DSA:3.60.15.10 105 220 7.6E-19 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TK0712 e3c27e80eb8b64c2baed55e8291ab9b2 220 Gene3D G3DSA:3.60.15.10 1 98 7.6E-20 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TK0712 e3c27e80eb8b64c2baed55e8291ab9b2 220 SUPERFAMILY SSF56281 5 194 7.08E-25 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TK1699 6cfb7c57430265c163560ae0ba30de82 190 Gene3D G3DSA:2.40.50.140 82 190 9.4E-35 T 31-10-2018 TK1699 6cfb7c57430265c163560ae0ba30de82 190 Pfam PF00575 S1 RNA binding domain 79 154 5.4E-15 T 31-10-2018 IPR003029 S1 domain GO:0003676 TK1699 6cfb7c57430265c163560ae0ba30de82 190 SUPERFAMILY SSF50249 81 179 1.04E-24 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold TK1699 6cfb7c57430265c163560ae0ba30de82 190 SMART SM00316 80 166 2.1E-17 T 31-10-2018 IPR022967 RNA-binding domain, S1 TK1699 6cfb7c57430265c163560ae0ba30de82 190 SUPERFAMILY SSF88798 1 77 1.7E-20 T 31-10-2018 IPR036898 RNA polymerase Rpb7-like, N-terminal domain superfamily GO:0003899|GO:0006351 TK1699 6cfb7c57430265c163560ae0ba30de82 190 TIGRFAM TIGR00448 rpoE: DNA-directed RNA polymerase 1 179 3.3E-65 T 31-10-2018 IPR004519 DNA-directed RNA polymerase, subunit E/RPC8 GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-1834949|Reactome: R-HSA-73780|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071 TK1699 6cfb7c57430265c163560ae0ba30de82 190 Gene3D G3DSA:3.30.1490.120 1 81 6.6E-32 T 31-10-2018 IPR036898 RNA polymerase Rpb7-like, N-terminal domain superfamily GO:0003899|GO:0006351 TK1699 6cfb7c57430265c163560ae0ba30de82 190 Pfam PF03876 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 8 77 1.8E-18 T 31-10-2018 IPR005576 RNA polymerase Rpb7, N-terminal GO:0003899|GO:0006351 TK1361 9e1ba6bc706a224974d9a39a37dc6535 810 Pfam PF17207 MCM OB domain 248 369 3.5E-18 T 31-10-2018 IPR033762 MCM OB domain Reactome: R-HSA-176187|Reactome: R-HSA-176974|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962 TK1361 9e1ba6bc706a224974d9a39a37dc6535 810 SUPERFAMILY SSF50249 161 388 1.03E-37 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold TK1361 9e1ba6bc706a224974d9a39a37dc6535 810 Gene3D G3DSA:2.20.28.10 275 321 1.1E-19 T 31-10-2018 TK1361 9e1ba6bc706a224974d9a39a37dc6535 810 SUPERFAMILY SSF52540 431 734 3.84E-34 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK1361 9e1ba6bc706a224974d9a39a37dc6535 810 Gene3D G3DSA:3.40.50.300 403 725 8.8E-94 T 31-10-2018 TK1361 9e1ba6bc706a224974d9a39a37dc6535 810 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 458 473 8.4E-24 T 31-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 TK1361 9e1ba6bc706a224974d9a39a37dc6535 810 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 547 560 8.4E-24 T 31-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 TK1361 9e1ba6bc706a224974d9a39a37dc6535 810 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 519 533 8.4E-24 T 31-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 TK1361 9e1ba6bc706a224974d9a39a37dc6535 810 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 598 606 8.4E-24 T 31-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 TK1361 9e1ba6bc706a224974d9a39a37dc6535 810 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 571 583 8.4E-24 T 31-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 TK1361 9e1ba6bc706a224974d9a39a37dc6535 810 SMART SM00382 459 598 1.1E-5 T 31-10-2018 IPR003593 AAA+ ATPase domain TK1361 9e1ba6bc706a224974d9a39a37dc6535 810 Pfam PF00493 MCM2/3/5 family 423 719 8.8E-92 T 31-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 TK1361 9e1ba6bc706a224974d9a39a37dc6535 810 Gene3D G3DSA:3.30.1640.10 149 241 1.0E-16 T 31-10-2018 TK1361 9e1ba6bc706a224974d9a39a37dc6535 810 SMART SM00350 242 720 1.5E-86 T 31-10-2018 IPR031327 Mini-chromosome maintenance protein TK0748 772dc2a100fcb31ff26c863862fef31c 169 PIRSF PIRSF016661 1 169 9.2E-42 T 31-10-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 TK0748 772dc2a100fcb31ff26c863862fef31c 169 Gene3D G3DSA:1.10.1760.20 1 168 3.7E-50 T 31-10-2018 TK0748 772dc2a100fcb31ff26c863862fef31c 169 Pfam PF02632 BioY family 26 163 4.3E-38 T 31-10-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 TK1694 623c203e2aad67374ae8f3dcf4060d09 63 SUPERFAMILY SSF54862 3 61 1.2E-14 T 31-10-2018 TK1694 623c203e2aad67374ae8f3dcf4060d09 63 Gene3D G3DSA:3.30.70.20 3 62 5.8E-22 T 31-10-2018 TK1694 623c203e2aad67374ae8f3dcf4060d09 63 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 7 59 7.0E-17 T 31-10-2018 TK1694 623c203e2aad67374ae8f3dcf4060d09 63 PRINTS PR00352 3Fe-4S ferredoxin signature 18 28 2.6E-9 T 31-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 TK1694 623c203e2aad67374ae8f3dcf4060d09 63 PRINTS PR00352 3Fe-4S ferredoxin signature 7 18 2.6E-9 T 31-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 TK1694 623c203e2aad67374ae8f3dcf4060d09 63 PRINTS PR00352 3Fe-4S ferredoxin signature 46 58 2.6E-9 T 31-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 TK1827 95376e66f904d9c97a9a39a4565df031 412 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 318 326 - T 31-10-2018 IPR018120 Glycoside hydrolase family 1, active site TK1827 95376e66f904d9c97a9a39a4565df031 412 SUPERFAMILY SSF51445 4 407 6.35E-130 T 31-10-2018 IPR017853 Glycoside hydrolase superfamily TK1827 95376e66f904d9c97a9a39a4565df031 412 Gene3D G3DSA:3.20.20.80 3 411 2.3E-150 T 31-10-2018 TK1827 95376e66f904d9c97a9a39a4565df031 412 PRINTS PR00131 Glycosyl hydrolase family 1 signature 318 326 7.7E-22 T 31-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TK1827 95376e66f904d9c97a9a39a4565df031 412 PRINTS PR00131 Glycosyl hydrolase family 1 signature 256 270 7.7E-22 T 31-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TK1827 95376e66f904d9c97a9a39a4565df031 412 PRINTS PR00131 Glycosyl hydrolase family 1 signature 330 341 7.7E-22 T 31-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TK1827 95376e66f904d9c97a9a39a4565df031 412 PRINTS PR00131 Glycosyl hydrolase family 1 signature 375 387 7.7E-22 T 31-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TK1827 95376e66f904d9c97a9a39a4565df031 412 PRINTS PR00131 Glycosyl hydrolase family 1 signature 351 368 7.7E-22 T 31-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TK1827 95376e66f904d9c97a9a39a4565df031 412 Pfam PF00232 Glycosyl hydrolase family 1 4 405 5.5E-89 T 31-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TK1971 e28b3a1dbc0f15f5e8575e6ca4f6ea00 174 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 139 145 - T 31-10-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 TK1971 e28b3a1dbc0f15f5e8575e6ca4f6ea00 174 Pfam PF09153 Domain of unknown function (DUF1938) 1 85 2.2E-41 T 31-10-2018 IPR015236 Domain of unknown function DUF1938 GO:0005737 TK1971 e28b3a1dbc0f15f5e8575e6ca4f6ea00 174 Hamap MF_00772 Methylated-DNA--protein-cysteine methyltransferase [ogt]. 18 168 36.656 T 31-10-2018 IPR023546 Methylated-DNA--protein-cysteine methyltransferase GO:0003824|GO:0006281 TK1971 e28b3a1dbc0f15f5e8575e6ca4f6ea00 174 Gene3D G3DSA:1.10.10.10 89 174 3.1E-35 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TK1971 e28b3a1dbc0f15f5e8575e6ca4f6ea00 174 Gene3D G3DSA:3.30.160.70 1 88 7.8E-60 T 31-10-2018 TK1971 e28b3a1dbc0f15f5e8575e6ca4f6ea00 174 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 90 167 2.0E-30 T 31-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 TK1971 e28b3a1dbc0f15f5e8575e6ca4f6ea00 174 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 91 169 4.5E-26 T 31-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 TK1971 e28b3a1dbc0f15f5e8575e6ca4f6ea00 174 SUPERFAMILY SSF53155 1 88 9.02E-36 T 31-10-2018 IPR036631 Methylated DNA-protein cysteine methyltransferase domain superfamily GO:0003908|GO:0006281 Reactome: R-HSA-5657655 TK1971 e28b3a1dbc0f15f5e8575e6ca4f6ea00 174 SUPERFAMILY SSF46767 90 169 1.01E-23 T 31-10-2018 IPR036217 Methylated DNA-protein cysteine methyltransferase, DNA binding domain Reactome: R-HSA-5657655 TK1971 e28b3a1dbc0f15f5e8575e6ca4f6ea00 174 ProDom PD068053 METHYLTRANSFERASE DNA METHYLATED-DNA--PROTEIN-CYSTEINE 6-O- O-6-METHYLGUANINE-DNA- REPAIR MGMT DAMAGE ALKYLTRANSFERASE METHYLGUANINE-DNA 1 96 3.0E-49 T 31-10-2018 IPR015236 Domain of unknown function DUF1938 GO:0005737 TK1337 85787283555c2fc7ebdc18c50469c333 252 Pfam PF00005 ABC transporter 19 162 8.4E-29 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TK1337 85787283555c2fc7ebdc18c50469c333 252 Gene3D G3DSA:3.40.50.300 1 243 2.7E-69 T 31-10-2018 TK1337 85787283555c2fc7ebdc18c50469c333 252 SUPERFAMILY SSF52540 6 227 6.79E-60 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK1337 85787283555c2fc7ebdc18c50469c333 252 SMART SM00382 28 211 1.8E-9 T 31-10-2018 IPR003593 AAA+ ATPase domain TK1516 40a9f741f19ff2c7b667ee096cf82b0c 174 Pfam PF01956 Integral membrane protein DUF106 13 173 2.9E-30 T 31-10-2018 IPR002809 Integral membrane protein EMC3/TMCO1-like GO:0016020 TK1516 40a9f741f19ff2c7b667ee096cf82b0c 174 SMART SM01415 10 173 1.8E-20 T 31-10-2018 IPR002809 Integral membrane protein EMC3/TMCO1-like GO:0016020 TK2218 52afca2660f4847eec88bc341a63a523 866 Gene3D G3DSA:1.10.8.60 710 773 6.2E-27 T 31-10-2018 TK2218 52afca2660f4847eec88bc341a63a523 866 Gene3D G3DSA:3.10.28.10 181 343 3.6E-29 T 31-10-2018 IPR027434 Homing endonuclease TK2218 52afca2660f4847eec88bc341a63a523 866 Gene3D G3DSA:3.40.50.300 598 709 4.8E-36 T 31-10-2018 TK2218 52afca2660f4847eec88bc341a63a523 866 SMART SM00305 557 605 1.9E-13 T 31-10-2018 IPR003586 Hint domain C-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TK2218 52afca2660f4847eec88bc341a63a523 866 Pfam PF08542 Replication factor C C-terminal domain 775 860 3.3E-21 T 31-10-2018 IPR013748 Replication factor C, C-terminal Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-176187|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804756|Reactome: R-HSA-69091|Reactome: R-HSA-69473 TK2218 52afca2660f4847eec88bc341a63a523 866 SUPERFAMILY SSF51294 59 599 4.32E-43 T 31-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TK2218 52afca2660f4847eec88bc341a63a523 866 SUPERFAMILY SSF48019 775 864 2.07E-23 T 31-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 TK2218 52afca2660f4847eec88bc341a63a523 866 Gene3D G3DSA:1.20.272.10 774 866 2.0E-36 T 31-10-2018 TK2218 52afca2660f4847eec88bc341a63a523 866 Pfam PF14890 Intein splicing domain 67 599 1.7E-28 T 31-10-2018 TK2218 52afca2660f4847eec88bc341a63a523 866 SUPERFAMILY SSF52540 600 757 2.08E-41 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK2218 52afca2660f4847eec88bc341a63a523 866 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 577 600 2.5E-7 T 31-10-2018 IPR030934 Intein C-terminal splicing region TK2218 52afca2660f4847eec88bc341a63a523 866 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 15 70 7.9E-6 T 31-10-2018 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 TK2218 52afca2660f4847eec88bc341a63a523 866 SMART SM00306 58 169 6.1E-30 T 31-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TK2218 52afca2660f4847eec88bc341a63a523 866 PRINTS PR00379 Intein signature 274 286 8.4E-16 T 31-10-2018 IPR006142 Intein GO:0016539 TK2218 52afca2660f4847eec88bc341a63a523 866 PRINTS PR00379 Intein signature 180 192 8.4E-16 T 31-10-2018 IPR006142 Intein GO:0016539 TK2218 52afca2660f4847eec88bc341a63a523 866 PRINTS PR00379 Intein signature 574 591 8.4E-16 T 31-10-2018 IPR006142 Intein GO:0016539 TK2218 52afca2660f4847eec88bc341a63a523 866 PRINTS PR00379 Intein signature 131 144 8.4E-16 T 31-10-2018 IPR006142 Intein GO:0016539 TK2218 52afca2660f4847eec88bc341a63a523 866 TIGRFAM TIGR01445 intein_Nterm: intein N-terminal splicing region 60 144 1.5E-16 T 31-10-2018 IPR006141 Intein N-terminal splicing region GO:0016539 Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TK2218 52afca2660f4847eec88bc341a63a523 866 Pfam PF01381 Helix-turn-helix 440 481 3.8E-7 T 31-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TK2218 52afca2660f4847eec88bc341a63a523 866 Gene3D G3DSA:2.170.16.10 536 597 1.1E-13 T 31-10-2018 TK2218 52afca2660f4847eec88bc341a63a523 866 Gene3D G3DSA:2.170.16.10 71 180 1.9E-19 T 31-10-2018 TK2218 52afca2660f4847eec88bc341a63a523 866 Pfam PF13177 DNA polymerase III, delta subunit 628 709 1.0E-10 T 31-10-2018 TK2218 52afca2660f4847eec88bc341a63a523 866 SMART SM00530 435 483 1.9E-5 T 31-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TK2218 52afca2660f4847eec88bc341a63a523 866 Gene3D G3DSA:1.10.260.40 434 488 2.4E-5 T 31-10-2018 TK2218 52afca2660f4847eec88bc341a63a523 866 SUPERFAMILY SSF55608 270 363 1.53E-19 T 31-10-2018 IPR027434 Homing endonuclease TK2218 52afca2660f4847eec88bc341a63a523 866 SUPERFAMILY SSF47413 440 482 2.19E-6 T 31-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TK2218 52afca2660f4847eec88bc341a63a523 866 Gene3D G3DSA:3.40.50.300 13 70 8.2E-16 T 31-10-2018 TK2218 52afca2660f4847eec88bc341a63a523 866 Pfam PF14528 LAGLIDADG-like domain 185 252 3.6E-6 T 31-10-2018 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 TK2218 52afca2660f4847eec88bc341a63a523 866 Pfam PF14528 LAGLIDADG-like domain 273 346 1.7E-18 T 31-10-2018 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 TK2218 52afca2660f4847eec88bc341a63a523 866 SUPERFAMILY SSF52540 12 60 5.22E-14 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK0638 a6bc17af871160fe02c772ad82aec846 747 Gene3D G3DSA:3.30.450.20 103 200 2.6E-29 T 31-10-2018 TK0638 a6bc17af871160fe02c772ad82aec846 747 Pfam PF02743 Cache domain 46 290 1.5E-43 T 31-10-2018 IPR033479 Double Cache domain 1 TK0638 a6bc17af871160fe02c772ad82aec846 747 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 532 667 6.1E-38 T 31-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TK0638 a6bc17af871160fe02c772ad82aec846 747 SUPERFAMILY SSF58104 410 745 6.54E-62 T 31-10-2018 TK0638 a6bc17af871160fe02c772ad82aec846 747 SMART SM00283 471 746 1.5E-64 T 31-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TK0638 a6bc17af871160fe02c772ad82aec846 747 Gene3D G3DSA:1.20.1480.50 301 403 7.4E-7 T 31-10-2018 TK0638 a6bc17af871160fe02c772ad82aec846 747 SUPERFAMILY SSF103190 117 209 1.69E-17 T 31-10-2018 IPR029151 Periplasmic sensor-like domain superfamily TK0638 a6bc17af871160fe02c772ad82aec846 747 Gene3D G3DSA:1.10.287.950 442 746 6.1E-65 T 31-10-2018 TK2286 f7fff7edf07b77ed04b49fc5ead23f70 115 SUPERFAMILY SSF50447 1 72 3.88E-17 T 31-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily TK2286 f7fff7edf07b77ed04b49fc5ead23f70 115 Gene3D G3DSA:2.40.10.230 1 75 5.1E-25 T 31-10-2018 IPR038664 H/ACA RNP complex subunit Gar1/Naf1, Cbf5-binding domain TK2286 f7fff7edf07b77ed04b49fc5ead23f70 115 ProDom PD064583 RNA-BINDING GAR1 COMPONENT RNP SNORNP HOMOLOG NUCLEOLAR PROCESSING RRNA VNG1366H 1 71 1.0E-34 T 31-10-2018 IPR020321 H/ACA ribonucleoprotein complex, subunit Gar1, archaea GO:0001522|GO:0042254 TK2286 f7fff7edf07b77ed04b49fc5ead23f70 115 Pfam PF04410 Gar1/Naf1 RNA binding region 2 58 1.5E-8 T 31-10-2018 IPR007504 H/ACA ribonucleoprotein complex, subunit Gar1/Naf1 GO:0001522|GO:0042254 TK2133 ec58c20cdb119f7e53deeff4139108d9 192 SUPERFAMILY SSF57903 136 187 3.31E-6 T 31-10-2018 IPR011011 Zinc finger, FYVE/PHD-type TK1518 cb949ab63c6f6c41fd258b6ffe1d56aa 482 PRINTS PR00303 Preprotein translocase SecY subunit signature 159 184 1.4E-7 T 31-10-2018 TK1518 cb949ab63c6f6c41fd258b6ffe1d56aa 482 PRINTS PR00303 Preprotein translocase SecY subunit signature 446 464 1.4E-7 T 31-10-2018 TK1518 cb949ab63c6f6c41fd258b6ffe1d56aa 482 PRINTS PR00303 Preprotein translocase SecY subunit signature 30 48 1.4E-7 T 31-10-2018 TK1518 cb949ab63c6f6c41fd258b6ffe1d56aa 482 PRINTS PR00303 Preprotein translocase SecY subunit signature 185 208 1.4E-7 T 31-10-2018 TK1518 cb949ab63c6f6c41fd258b6ffe1d56aa 482 SUPERFAMILY SSF103491 7 468 7.45E-109 T 31-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TK1518 cb949ab63c6f6c41fd258b6ffe1d56aa 482 Hamap MF_01465 Protein translocase subunit SecY [secY]. 17 477 20.934 T 31-10-2018 IPR026593 Protein translocase subunit SecY TK1518 cb949ab63c6f6c41fd258b6ffe1d56aa 482 PIRSF PIRSF004557 5 482 3.4E-100 T 31-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TK1518 cb949ab63c6f6c41fd258b6ffe1d56aa 482 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 27 470 3.6E-89 T 31-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TK1518 cb949ab63c6f6c41fd258b6ffe1d56aa 482 Pfam PF00344 SecY translocase 72 461 1.3E-70 T 31-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TK1518 cb949ab63c6f6c41fd258b6ffe1d56aa 482 ProSitePatterns PS00756 Protein secY signature 2. 178 195 - T 31-10-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TK1518 cb949ab63c6f6c41fd258b6ffe1d56aa 482 Gene3D G3DSA:1.10.3370.10 26 482 1.4E-179 T 31-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TK1518 cb949ab63c6f6c41fd258b6ffe1d56aa 482 ProSitePatterns PS00755 Protein secY signature 1. 72 91 - T 31-10-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TK1518 cb949ab63c6f6c41fd258b6ffe1d56aa 482 Pfam PF10559 Plug domain of Sec61p 38 71 1.9E-11 T 31-10-2018 IPR019561 Translocon Sec61/SecY, plug domain Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TK1599 89c7b3c9d053b586bb563f15dbb98eb0 203 SUPERFAMILY SSF81573 13 67 3.34E-5 T 31-10-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain superfamily TK1599 89c7b3c9d053b586bb563f15dbb98eb0 203 Gene3D G3DSA:3.30.2320.30 100 203 6.7E-24 T 31-10-2018 IPR038495 V-type ATPase subunit E, C-terminal domain superfamily Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TK1599 89c7b3c9d053b586bb563f15dbb98eb0 203 SUPERFAMILY SSF160527 81 203 1.02E-24 T 31-10-2018 TK1599 89c7b3c9d053b586bb563f15dbb98eb0 203 Hamap MF_00311 V-type proton ATPase subunit E [atpE]. 2 203 15.416 T 31-10-2018 IPR002842 V-type ATPase subunit E GO:0015991|GO:0033178|GO:0046961 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TK1599 89c7b3c9d053b586bb563f15dbb98eb0 203 Gene3D G3DSA:1.20.5.620 18 98 5.0E-26 T 31-10-2018 TK1599 89c7b3c9d053b586bb563f15dbb98eb0 203 Pfam PF01991 ATP synthase (E/31 kDa) subunit 10 202 1.3E-39 T 31-10-2018 IPR002842 V-type ATPase subunit E GO:0015991|GO:0033178|GO:0046961 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TK1272 dfec7ed391582d4b5912453cb96a25eb 211 Pfam PF13545 Crp-like helix-turn-helix domain 7 65 1.6E-10 T 31-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 TK1272 dfec7ed391582d4b5912453cb96a25eb 211 Gene3D G3DSA:1.10.10.10 1 83 1.3E-17 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TK1272 dfec7ed391582d4b5912453cb96a25eb 211 SUPERFAMILY SSF46785 15 80 1.52E-13 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TK1272 dfec7ed391582d4b5912453cb96a25eb 211 Gene3D G3DSA:2.40.30.30 84 211 6.1E-41 T 31-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 TK1272 dfec7ed391582d4b5912453cb96a25eb 211 Pfam PF01982 Domain of unknown function DUF120 92 209 2.5E-38 T 31-10-2018 IPR023602 Riboflavin kinase domain, CTP-dependent GO:0016773 KEGG: 00740+2.7.1.161|MetaCyc: PWY-6167 TK1272 dfec7ed391582d4b5912453cb96a25eb 211 Hamap MF_01285 Riboflavin kinase [ribK]. 86 209 25.12 T 31-10-2018 IPR023470 Riboflavin kinase, archaeal GO:0008531|GO:0009231 KEGG: 00740+2.7.1.161|MetaCyc: PWY-6167 TK1272 dfec7ed391582d4b5912453cb96a25eb 211 SUPERFAMILY SSF82114 86 209 1.31E-40 T 31-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 TK1272 dfec7ed391582d4b5912453cb96a25eb 211 SMART SM00419 14 66 3.3E-9 T 31-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 TK0990 9e4e24ee202ffcdcece189f078c3fbdf 595 Gene3D G3DSA:3.20.20.70 1 458 3.5E-167 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TK0990 9e4e24ee202ffcdcece189f078c3fbdf 595 SUPERFAMILY SSF51569 1 301 1.42E-87 T 31-10-2018 TK0990 9e4e24ee202ffcdcece189f078c3fbdf 595 SUPERFAMILY SSF51230 521 594 1.7E-25 T 31-10-2018 IPR011053 Single hybrid motif TK0990 9e4e24ee202ffcdcece189f078c3fbdf 595 Pfam PF02436 Conserved carboxylase domain 292 474 4.7E-59 T 31-10-2018 IPR003379 Carboxylase, conserved domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 TK0990 9e4e24ee202ffcdcece189f078c3fbdf 595 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 551 568 - T 31-10-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 TK0990 9e4e24ee202ffcdcece189f078c3fbdf 595 SUPERFAMILY SSF89000 297 446 7.85E-56 T 31-10-2018 TK0990 9e4e24ee202ffcdcece189f078c3fbdf 595 TIGRFAM TIGR01108 oadA: oxaloacetate decarboxylase alpha subunit 6 590 3.1E-229 T 31-10-2018 IPR005776 Oxaloacetate decarboxylase, alpha subunit GO:0006814|GO:0008948 TK0990 9e4e24ee202ffcdcece189f078c3fbdf 595 Gene3D G3DSA:2.40.50.100 523 595 4.4E-29 T 31-10-2018 TK0990 9e4e24ee202ffcdcece189f078c3fbdf 595 Pfam PF00682 HMGL-like 3 234 2.2E-41 T 31-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 TK0990 9e4e24ee202ffcdcece189f078c3fbdf 595 Pfam PF00364 Biotin-requiring enzyme 529 594 1.8E-24 T 31-10-2018 IPR000089 Biotin/lipoyl attachment TK1677 d2217581e0cb36876318fcb3b562295d 263 SUPERFAMILY SSF51735 13 261 1.33E-70 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily TK1677 d2217581e0cb36876318fcb3b562295d 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 87 98 6.4E-39 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TK1677 d2217581e0cb36876318fcb3b562295d 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 6.4E-39 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TK1677 d2217581e0cb36876318fcb3b562295d 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 6.4E-39 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TK1677 d2217581e0cb36876318fcb3b562295d 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 224 244 6.4E-39 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TK1677 d2217581e0cb36876318fcb3b562295d 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 15 32 6.4E-39 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TK1677 d2217581e0cb36876318fcb3b562295d 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 149 6.4E-39 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TK1677 d2217581e0cb36876318fcb3b562295d 263 Gene3D G3DSA:3.40.50.720 2 262 1.4E-70 T 31-10-2018 TK1677 d2217581e0cb36876318fcb3b562295d 263 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 20 260 4.0E-56 T 31-10-2018 TK1677 d2217581e0cb36876318fcb3b562295d 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 87 98 4.2E-10 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TK1677 d2217581e0cb36876318fcb3b562295d 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 160 179 4.2E-10 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TK1677 d2217581e0cb36876318fcb3b562295d 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 139 147 4.2E-10 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TK1903 902c0456425ea1d1f59c9257c3263def 1798 Pfam PF03833 DNA polymerase II large subunit DP2 13 963 0.0 T 31-10-2018 IPR016033 DNA polymerase II large subunit DP2, N-terminal KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TK1903 902c0456425ea1d1f59c9257c3263def 1798 Hamap MF_00324 DNA polymerase II large subunit [polC]. 1 1702 402.652 T 31-10-2018 IPR004475 DNA polymerase II large subunit DP2 GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TK1903 902c0456425ea1d1f59c9257c3263def 1798 SUPERFAMILY SSF55608 1263 1384 3.68E-10 T 31-10-2018 IPR027434 Homing endonuclease TK1903 902c0456425ea1d1f59c9257c3263def 1798 Gene3D G3DSA:3.10.28.10 1179 1337 1.8E-28 T 31-10-2018 IPR027434 Homing endonuclease TK1903 902c0456425ea1d1f59c9257c3263def 1798 SMART SM00306 962 1084 5.3E-28 T 31-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TK1903 902c0456425ea1d1f59c9257c3263def 1798 SMART SM00305 1395 1443 0.0019 T 31-10-2018 IPR003586 Hint domain C-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TK1903 902c0456425ea1d1f59c9257c3263def 1798 PRINTS PR00379 Intein signature 1277 1289 8.2E-7 T 31-10-2018 IPR006142 Intein GO:0016539 TK1903 902c0456425ea1d1f59c9257c3263def 1798 PRINTS PR00379 Intein signature 1047 1060 8.2E-7 T 31-10-2018 IPR006142 Intein GO:0016539 TK1903 902c0456425ea1d1f59c9257c3263def 1798 PRINTS PR00379 Intein signature 1181 1193 8.2E-7 T 31-10-2018 IPR006142 Intein GO:0016539 TK1903 902c0456425ea1d1f59c9257c3263def 1798 PRINTS PR00379 Intein signature 1413 1430 8.2E-7 T 31-10-2018 IPR006142 Intein GO:0016539 TK1903 902c0456425ea1d1f59c9257c3263def 1798 TIGRFAM TIGR00354 polC: DNA polymerase II, large subunit DP2 9 972 0.0 T 31-10-2018 IPR004475 DNA polymerase II large subunit DP2 GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TK1903 902c0456425ea1d1f59c9257c3263def 1798 SUPERFAMILY SSF51294 964 1438 7.65E-34 T 31-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TK1903 902c0456425ea1d1f59c9257c3263def 1798 Gene3D G3DSA:2.170.16.10 1367 1437 8.4E-16 T 31-10-2018 TK1903 902c0456425ea1d1f59c9257c3263def 1798 Gene3D G3DSA:2.170.16.10 964 1140 2.9E-46 T 31-10-2018 TK1903 902c0456425ea1d1f59c9257c3263def 1798 TIGRFAM TIGR01445 intein_Nterm: intein N-terminal splicing region 964 1060 7.8E-15 T 31-10-2018 IPR006141 Intein N-terminal splicing region GO:0016539 Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TK1903 902c0456425ea1d1f59c9257c3263def 1798 Pfam PF14528 LAGLIDADG-like domain 1276 1370 3.2E-11 T 31-10-2018 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 TK1903 902c0456425ea1d1f59c9257c3263def 1798 Pfam PF14890 Intein splicing domain 1007 1436 5.8E-27 T 31-10-2018 TK1554 6236cd5da5a6e7c0182c04f09e887993 426 Pfam PF13632 Glycosyl transferase family group 2 166 385 3.8E-26 T 31-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TK1554 6236cd5da5a6e7c0182c04f09e887993 426 Gene3D G3DSA:3.90.550.10 63 297 1.8E-37 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TK1554 6236cd5da5a6e7c0182c04f09e887993 426 SUPERFAMILY SSF53448 68 347 1.17E-49 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TK0360 433c2690a02a5d2ee964bd485602206d 312 SUPERFAMILY SSF53335 22 306 1.15E-61 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TK0360 433c2690a02a5d2ee964bd485602206d 312 TIGRFAM TIGR00446 nop2p: NOL1/NOP2/sun family putative RNA methylase 39 306 1.2E-92 T 31-10-2018 IPR011023 Nop2p GO:0003723|GO:0006364|GO:0008757 Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 TK0360 433c2690a02a5d2ee964bd485602206d 312 Gene3D G3DSA:3.40.50.150 101 311 3.3E-73 T 31-10-2018 TK0360 433c2690a02a5d2ee964bd485602206d 312 Pfam PF17125 N-terminal domain of 16S rRNA methyltransferase RsmF 13 97 1.3E-16 T 31-10-2018 IPR031341 Ribosomal RNA small subunit methyltransferase F, N-terminal Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 TK0360 433c2690a02a5d2ee964bd485602206d 312 Pfam PF01189 16S rRNA methyltransferase RsmB/F 101 304 3.8E-53 T 31-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 TK0360 433c2690a02a5d2ee964bd485602206d 312 Gene3D G3DSA:3.30.70.3130 5 96 6.2E-17 T 31-10-2018 TK0360 433c2690a02a5d2ee964bd485602206d 312 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 228 244 4.3E-23 T 31-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TK0360 433c2690a02a5d2ee964bd485602206d 312 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 83 97 4.3E-23 T 31-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TK0360 433c2690a02a5d2ee964bd485602206d 312 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 112 122 4.3E-23 T 31-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TK0360 433c2690a02a5d2ee964bd485602206d 312 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 178 190 4.3E-23 T 31-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TK0360 433c2690a02a5d2ee964bd485602206d 312 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 289 306 4.3E-23 T 31-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TK1315 6e6a583a8dda19ea7cf46734ea70a351 631 SUPERFAMILY SSF52402 223 417 5.35E-45 T 31-10-2018 TK1315 6e6a583a8dda19ea7cf46734ea70a351 631 Pfam PF01472 PUA domain 134 204 5.7E-16 T 31-10-2018 IPR002478 PUA domain GO:0003723 TK1315 6e6a583a8dda19ea7cf46734ea70a351 631 SUPERFAMILY SSF54862 558 623 1.16E-14 T 31-10-2018 TK1315 6e6a583a8dda19ea7cf46734ea70a351 631 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 576 587 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TK1315 6e6a583a8dda19ea7cf46734ea70a351 631 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 253 429 1.0E-44 T 31-10-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824 Reactome: R-HSA-196843 TK1315 6e6a583a8dda19ea7cf46734ea70a351 631 Pfam PF12838 4Fe-4S dicluster domain 576 618 1.2E-9 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TK1315 6e6a583a8dda19ea7cf46734ea70a351 631 SMART SM00359 133 207 9.8E-17 T 31-10-2018 IPR002478 PUA domain GO:0003723 TK1315 6e6a583a8dda19ea7cf46734ea70a351 631 Gene3D G3DSA:3.40.50.620 218 442 9.8E-49 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TK1315 6e6a583a8dda19ea7cf46734ea70a351 631 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 607 618 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TK1315 6e6a583a8dda19ea7cf46734ea70a351 631 TIGRFAM TIGR00451 unchar_dom_2: uncharacterized domain 2 120 201 8.8E-9 T 31-10-2018 IPR004521 Uncharacterised domain CHP00451 GO:0003723 TK1315 6e6a583a8dda19ea7cf46734ea70a351 631 Gene3D G3DSA:3.30.70.20 570 622 1.1E-10 T 31-10-2018 TK1315 6e6a583a8dda19ea7cf46734ea70a351 631 SUPERFAMILY SSF88697 132 204 1.88E-18 T 31-10-2018 IPR015947 PUA-like superfamily TK1315 6e6a583a8dda19ea7cf46734ea70a351 631 Gene3D G3DSA:2.30.130.10 130 205 8.9E-16 T 31-10-2018 IPR036974 PUA domain superfamily GO:0003723 TK2166 66c24d110222bdab34cb588a2461ddc0 372 SUPERFAMILY SSF55031 167 277 3.29E-13 T 31-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain TK2166 66c24d110222bdab34cb588a2461ddc0 372 Gene3D G3DSA:3.30.70.360 168 279 5.0E-75 T 31-10-2018 TK2166 66c24d110222bdab34cb588a2461ddc0 372 Pfam PF01546 Peptidase family M20/M25/M40 62 366 1.1E-29 T 31-10-2018 IPR002933 Peptidase M20 GO:0016787 TK2166 66c24d110222bdab34cb588a2461ddc0 372 Pfam PF07687 Peptidase dimerisation domain 165 267 1.7E-9 T 31-10-2018 IPR011650 Peptidase M20, dimerisation domain TK2166 66c24d110222bdab34cb588a2461ddc0 372 SUPERFAMILY SSF53187 4 369 3.02E-53 T 31-10-2018 TK2166 66c24d110222bdab34cb588a2461ddc0 372 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 94 132 - T 31-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 TK2166 66c24d110222bdab34cb588a2461ddc0 372 Gene3D G3DSA:3.40.630.10 6 356 5.0E-75 T 31-10-2018 TK1523 11f13ee759aa47e2fc121b5616eb7d10 150 ProSitePatterns PS00526 Ribosomal protein L19e signature. 7 26 - T 31-10-2018 IPR023638 Ribosomal protein L19/L19e conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1523 11f13ee759aa47e2fc121b5616eb7d10 150 Gene3D G3DSA:1.10.1650.10 1 56 7.5E-26 T 31-10-2018 IPR015972 Ribosomal protein L19/L19e, domain 1 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1523 11f13ee759aa47e2fc121b5616eb7d10 150 SMART SM01416 3 146 1.7E-87 T 31-10-2018 IPR000196 Ribosomal protein L19/L19e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1523 11f13ee759aa47e2fc121b5616eb7d10 150 Hamap MF_01475 50S ribosomal protein L19e [rpl19e]. 3 149 25.686 T 31-10-2018 IPR000196 Ribosomal protein L19/L19e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1523 11f13ee759aa47e2fc121b5616eb7d10 150 Gene3D G3DSA:1.10.1200.240 58 149 5.3E-30 T 31-10-2018 TK1523 11f13ee759aa47e2fc121b5616eb7d10 150 SUPERFAMILY SSF48140 3 143 4.05E-57 T 31-10-2018 IPR035970 Ribosomal protein L19/L19e superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1523 11f13ee759aa47e2fc121b5616eb7d10 150 Pfam PF01280 Ribosomal protein L19e 4 145 2.2E-58 T 31-10-2018 IPR000196 Ribosomal protein L19/L19e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1145 d1f98bd7be7b04d0e8a42e8a30df187d 256 PIRSF PIRSF006648 1 255 7.5E-77 T 31-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 TK1145 d1f98bd7be7b04d0e8a42e8a30df187d 256 TIGRFAM TIGR01247 drrB: daunorubicin resistance ABC transporter membrane protein 10 250 3.9E-106 T 31-10-2018 IPR005942 Daunorubicin resistance ABC transporter membrane protein TK1145 d1f98bd7be7b04d0e8a42e8a30df187d 256 PRINTS PR00164 ABC-2 type transport system membrane protein signature 196 215 5.2E-12 T 31-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 TK1145 d1f98bd7be7b04d0e8a42e8a30df187d 256 PRINTS PR00164 ABC-2 type transport system membrane protein signature 22 43 5.2E-12 T 31-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 TK1145 d1f98bd7be7b04d0e8a42e8a30df187d 256 PRINTS PR00164 ABC-2 type transport system membrane protein signature 139 163 5.2E-12 T 31-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 TK1145 d1f98bd7be7b04d0e8a42e8a30df187d 256 PRINTS PR00164 ABC-2 type transport system membrane protein signature 176 195 5.2E-12 T 31-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 TK1145 d1f98bd7be7b04d0e8a42e8a30df187d 256 Pfam PF01061 ABC-2 type transporter 4 216 2.2E-42 T 31-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 TK2275 773c395ad75ec8ff935fe441fe854635 172 TIGRFAM TIGR00451 unchar_dom_2: uncharacterized domain 2 53 164 1.6E-30 T 31-10-2018 IPR004521 Uncharacterised domain CHP00451 GO:0003723 TK2275 773c395ad75ec8ff935fe441fe854635 172 Gene3D G3DSA:3.10.450.120 1 78 2.5E-36 T 31-10-2018 TK2275 773c395ad75ec8ff935fe441fe854635 172 SMART SM00359 88 163 1.7E-21 T 31-10-2018 IPR002478 PUA domain GO:0003723 TK2275 773c395ad75ec8ff935fe441fe854635 172 SUPERFAMILY SSF88697 88 169 1.99E-23 T 31-10-2018 IPR015947 PUA-like superfamily TK2275 773c395ad75ec8ff935fe441fe854635 172 TIGRFAM TIGR03684 arCOG00985: arCOG04150 universal archaeal PUA-domain protein 6 168 2.2E-59 T 31-10-2018 IPR022430 Conserved hypothetical protein CHP03684 TK2275 773c395ad75ec8ff935fe441fe854635 172 Gene3D G3DSA:2.30.130.10 79 171 4.1E-35 T 31-10-2018 IPR036974 PUA domain superfamily GO:0003723 TK2275 773c395ad75ec8ff935fe441fe854635 172 PIRSF PIRSF005067 1 172 6.3E-43 T 31-10-2018 IPR016437 MCT-1/Tma20 TK2275 773c395ad75ec8ff935fe441fe854635 172 Pfam PF01472 PUA domain 89 161 2.2E-23 T 31-10-2018 IPR002478 PUA domain GO:0003723 TK2275 773c395ad75ec8ff935fe441fe854635 172 Pfam PF09183 Domain of unknown function (DUF1947) 6 75 1.1E-6 T 31-10-2018 IPR015266 Domain of unknown function DUF1947 TK1135 d47f492ac38c94be3b8d6230a737de23 324 PIRSF PIRSF004954 1 318 3.6E-100 T 31-10-2018 IPR005909 Conserved hypothetical protein CHP01210 TK1135 d47f492ac38c94be3b8d6230a737de23 324 TIGRFAM TIGR01210 TIGR01210: radical SAM enzyme, TIGR01210 family 3 321 1.7E-125 T 31-10-2018 IPR005909 Conserved hypothetical protein CHP01210 TK1135 d47f492ac38c94be3b8d6230a737de23 324 Pfam PF04055 Radical SAM superfamily 35 180 1.5E-7 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TK1135 d47f492ac38c94be3b8d6230a737de23 324 SMART SM00729 17 247 1.8E-23 T 31-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TK1135 d47f492ac38c94be3b8d6230a737de23 324 SUPERFAMILY SSF102114 12 256 1.05E-14 T 31-10-2018 TK0296 5c4fb3908d088d1b2ed26538785c80cf 302 Gene3D G3DSA:3.40.50.10800 173 257 7.6E-123 T 31-10-2018 TK0296 5c4fb3908d088d1b2ed26538785c80cf 302 Hamap MF_00568 Quinolinate synthase A [nadA]. 4 301 45.455 T 31-10-2018 IPR023066 Quinolinate synthase A, type 2 GO:0016765 MetaCyc: PWY-5316|MetaCyc: PWY-7342 TK0296 5c4fb3908d088d1b2ed26538785c80cf 302 TIGRFAM TIGR00550 nadA: quinolinate synthetase complex, A subunit 2 302 1.4E-114 T 31-10-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 TK0296 5c4fb3908d088d1b2ed26538785c80cf 302 SUPERFAMILY SSF142754 5 301 3.27E-115 T 31-10-2018 IPR036094 Quinolinate synthetase A superfamily GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 TK0296 5c4fb3908d088d1b2ed26538785c80cf 302 Gene3D G3DSA:3.40.50.10800 8 282 7.6E-123 T 31-10-2018 TK0296 5c4fb3908d088d1b2ed26538785c80cf 302 Pfam PF02445 Quinolinate synthetase A protein 8 300 9.4E-112 T 31-10-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 TK0296 5c4fb3908d088d1b2ed26538785c80cf 302 Gene3D G3DSA:3.40.50.10800 88 300 7.6E-123 T 31-10-2018 TK0463 fe3e5dbe5a2a54546bada88da2a0445f 490 TIGRFAM TIGR01908 cas_CXXC_CXXC: CRISPR-associated protein Cas8b1/Cst1, subtype I-B/TNEAP 127 429 8.0E-79 T 31-10-2018 IPR010180 CRISPR-associated protein, CXXC-CXXC TK0463 fe3e5dbe5a2a54546bada88da2a0445f 490 Pfam PF09706 CRISPR-associated protein (Cas_CXXC_CXXC) 130 189 3.3E-11 T 31-10-2018 IPR019121 CRISPR-associated protein, CXXC-CXXC domain TK0706 611ed18d3a0a3787613252c234952288 544 Gene3D G3DSA:3.40.50.1980 212 542 2.9E-91 T 31-10-2018 TK0706 611ed18d3a0a3787613252c234952288 544 SUPERFAMILY SSF56524 61 232 2.75E-19 T 31-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 TK0706 611ed18d3a0a3787613252c234952288 544 Pfam PF00174 Oxidoreductase molybdopterin binding domain 89 217 1.4E-7 T 31-10-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 TK0706 611ed18d3a0a3787613252c234952288 544 SUPERFAMILY SSF53807 228 535 8.83E-74 T 31-10-2018 TK0706 611ed18d3a0a3787613252c234952288 544 Pfam PF01497 Periplasmic binding protein 244 485 5.4E-38 T 31-10-2018 IPR002491 ABC transporter periplasmic binding domain TK0523 c33ac996751fd211977034abd50bbf95 171 Gene3D G3DSA:1.20.1260.10 2 132 1.5E-46 T 31-10-2018 IPR012347 Ferritin-like TK0523 c33ac996751fd211977034abd50bbf95 171 SUPERFAMILY SSF57802 137 170 1.43E-10 T 31-10-2018 TK0523 c33ac996751fd211977034abd50bbf95 171 Gene3D G3DSA:2.20.28.10 133 171 6.0E-19 T 31-10-2018 TK0523 c33ac996751fd211977034abd50bbf95 171 Pfam PF02915 Rubrerythrin 10 124 8.2E-25 T 31-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 TK0523 c33ac996751fd211977034abd50bbf95 171 SUPERFAMILY SSF47240 3 132 1.43E-37 T 31-10-2018 IPR009078 Ferritin-like superfamily TK1022 3118a4bb5ecf15365aec167761d265df 279 Gene3D G3DSA:3.30.1360.130 118 263 6.1E-75 T 31-10-2018 TK1022 3118a4bb5ecf15365aec167761d265df 279 SUPERFAMILY SSF63992 1 275 7.06E-86 T 31-10-2018 IPR036177 Peptidase M55, D-aminopeptidase superfamily TK1022 3118a4bb5ecf15365aec167761d265df 279 Gene3D G3DSA:3.40.50.10780 1 217 6.1E-75 T 31-10-2018 IPR027476 D-aminopeptidase, N-terminal TK1022 3118a4bb5ecf15365aec167761d265df 279 Pfam PF04951 D-aminopeptidase 1 265 1.2E-83 T 31-10-2018 IPR007035 Peptidase M55, D-aminopeptidase TK1022 3118a4bb5ecf15365aec167761d265df 279 PIRSF PIRSF015853 1 277 6.1E-102 T 31-10-2018 IPR007035 Peptidase M55, D-aminopeptidase TK1129 8fbf81f6dabcbba893dcd328b935959b 288 SUPERFAMILY SSF52518 19 270 2.21E-75 T 31-10-2018 IPR029061 Thiamin diphosphate-binding fold TK1129 8fbf81f6dabcbba893dcd328b935959b 288 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 57 205 2.5E-40 T 31-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 TK1129 8fbf81f6dabcbba893dcd328b935959b 288 Gene3D G3DSA:3.40.50.970 70 271 2.0E-33 T 31-10-2018 TK2196 7246208ae9a0c7bbfa7573e1037bfe0c 310 PRINTS PR00101 Aspartate carbamoyltransferase signature 286 300 1.6E-38 T 31-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TK2196 7246208ae9a0c7bbfa7573e1037bfe0c 310 PRINTS PR00101 Aspartate carbamoyltransferase signature 134 151 1.6E-38 T 31-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TK2196 7246208ae9a0c7bbfa7573e1037bfe0c 310 PRINTS PR00101 Aspartate carbamoyltransferase signature 225 234 1.6E-38 T 31-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TK2196 7246208ae9a0c7bbfa7573e1037bfe0c 310 PRINTS PR00101 Aspartate carbamoyltransferase signature 264 269 1.6E-38 T 31-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TK2196 7246208ae9a0c7bbfa7573e1037bfe0c 310 PRINTS PR00101 Aspartate carbamoyltransferase signature 41 63 1.6E-38 T 31-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TK2196 7246208ae9a0c7bbfa7573e1037bfe0c 310 PRINTS PR00101 Aspartate carbamoyltransferase signature 80 89 1.6E-38 T 31-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TK2196 7246208ae9a0c7bbfa7573e1037bfe0c 310 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 154 302 2.1E-30 T 31-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 TK2196 7246208ae9a0c7bbfa7573e1037bfe0c 310 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 5 307 39.702 T 31-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TK2196 7246208ae9a0c7bbfa7573e1037bfe0c 310 Gene3D G3DSA:3.40.50.1370 135 292 1.7E-125 T 31-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 TK2196 7246208ae9a0c7bbfa7573e1037bfe0c 310 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 6 304 3.3E-133 T 31-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TK2196 7246208ae9a0c7bbfa7573e1037bfe0c 310 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 6 147 4.3E-50 T 31-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 TK2196 7246208ae9a0c7bbfa7573e1037bfe0c 310 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 135 146 2.6E-23 T 31-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TK2196 7246208ae9a0c7bbfa7573e1037bfe0c 310 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 270 293 2.6E-23 T 31-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TK2196 7246208ae9a0c7bbfa7573e1037bfe0c 310 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 260 269 2.6E-23 T 31-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TK2196 7246208ae9a0c7bbfa7573e1037bfe0c 310 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 51 70 2.6E-23 T 31-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TK2196 7246208ae9a0c7bbfa7573e1037bfe0c 310 SUPERFAMILY SSF53671 2 306 1.01E-103 T 31-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 TK2196 7246208ae9a0c7bbfa7573e1037bfe0c 310 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 51 58 - T 31-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TK2196 7246208ae9a0c7bbfa7573e1037bfe0c 310 Gene3D G3DSA:3.40.50.1370 7 301 1.7E-125 T 31-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 TK2053 1c1f9a4ef17619add7c75633c86d3b6c 305 Pfam PF13732 Domain of unknown function (DUF4162) 221 304 2.3E-7 T 31-10-2018 IPR025302 Domain of unknown function DUF4162 TK2053 1c1f9a4ef17619add7c75633c86d3b6c 305 SUPERFAMILY SSF52540 2 229 6.41E-58 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK2053 1c1f9a4ef17619add7c75633c86d3b6c 305 Pfam PF00005 ABC transporter 17 167 2.4E-30 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TK2053 1c1f9a4ef17619add7c75633c86d3b6c 305 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TK2053 1c1f9a4ef17619add7c75633c86d3b6c 305 Gene3D G3DSA:3.40.50.300 1 241 4.5E-61 T 31-10-2018 TK2053 1c1f9a4ef17619add7c75633c86d3b6c 305 SMART SM00382 26 219 7.4E-13 T 31-10-2018 IPR003593 AAA+ ATPase domain TK2033 f2375d42ad9dbe49d7b7307a7ece0209 195 ProDom PD016744 UPF0215 ST0304 TK2033 MA4269 PAE0952 SSO0256 NEQ431 MK0057 PTO0905 TV0037 72 184 3.0E-59 T 31-10-2018 IPR002802 Protein of unknown function DUF99 TK2033 f2375d42ad9dbe49d7b7307a7ece0209 195 Gene3D G3DSA:3.30.2170.10 3 195 4.4E-61 T 31-10-2018 TK2033 f2375d42ad9dbe49d7b7307a7ece0209 195 Pfam PF01949 Protein of unknown function DUF99 8 188 8.1E-65 T 31-10-2018 IPR002802 Protein of unknown function DUF99 TK2033 f2375d42ad9dbe49d7b7307a7ece0209 195 PIRSF PIRSF006380 1 195 1.7E-69 T 31-10-2018 IPR002802 Protein of unknown function DUF99 TK2033 f2375d42ad9dbe49d7b7307a7ece0209 195 Hamap MF_00582 UPF0215 protein . 9 189 33.833 T 31-10-2018 IPR002802 Protein of unknown function DUF99 TK0191 206e87286933ba56ff41088663bdd78a 149 SUPERFAMILY SSF88723 1 143 4.77E-16 T 31-10-2018 IPR029060 PIN-like domain superfamily TK0191 206e87286933ba56ff41088663bdd78a 149 Pfam PF01850 PIN domain 3 125 2.1E-9 T 31-10-2018 IPR002716 PIN domain TK0191 206e87286933ba56ff41088663bdd78a 149 Gene3D G3DSA:3.40.50.1010 1 129 4.1E-12 T 31-10-2018 TK2274 2da5667131b2f2c0cf8ceafc7549386d 149 Hamap MF_02115 FAD synthase [ribL]. 8 148 30.128 T 31-10-2018 IPR024902 FAD synthase RibL GO:0003919|GO:0006747|GO:0046444 KEGG: 00740+2.7.7.2|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TK2274 2da5667131b2f2c0cf8ceafc7549386d 149 SUPERFAMILY SSF52374 8 143 1.97E-27 T 31-10-2018 TK2274 2da5667131b2f2c0cf8ceafc7549386d 149 Gene3D G3DSA:3.40.50.620 1 147 4.9E-42 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TK2274 2da5667131b2f2c0cf8ceafc7549386d 149 Pfam PF01467 Cytidylyltransferase-like 11 142 4.9E-25 T 31-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 TK2274 2da5667131b2f2c0cf8ceafc7549386d 149 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 9 75 4.5E-21 T 31-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 TK0203 03cccde915b87a837339112d1dfaebed 380 Gene3D G3DSA:3.30.1490.20 152 218 3.7E-94 T 31-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 TK0203 03cccde915b87a837339112d1dfaebed 380 Gene3D G3DSA:3.30.470.20 122 379 3.7E-94 T 31-10-2018 TK0203 03cccde915b87a837339112d1dfaebed 380 Pfam PF06849 Protein of unknown function (DUF1246) 21 153 8.1E-44 T 31-10-2018 IPR010672 IMP biosynthesis enzyme PurP, N-terminal GO:0000287|GO:0005524|GO:0006188|GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 TK0203 03cccde915b87a837339112d1dfaebed 380 Gene3D G3DSA:3.40.50.20 1 121 2.8E-43 T 31-10-2018 TK0203 03cccde915b87a837339112d1dfaebed 380 SUPERFAMILY SSF56059 139 380 2.09E-76 T 31-10-2018 TK0203 03cccde915b87a837339112d1dfaebed 380 PIRSF PIRSF004602 1 380 1.0E-144 T 31-10-2018 IPR023656 IMP biosynthesis enzyme PurP GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 TK0203 03cccde915b87a837339112d1dfaebed 380 Pfam PF06973 Domain of unknown function (DUF1297) 189 380 1.3E-80 T 31-10-2018 IPR009720 IMP biosynthesis enzyme PurP, C-terminal GO:0000287|GO:0005524|GO:0006188|GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 TK0203 03cccde915b87a837339112d1dfaebed 380 SUPERFAMILY SSF52440 1 133 1.73E-42 T 31-10-2018 IPR016185 Pre-ATP-grasp domain superfamily TK0332 3ff48a0bd584d754809bd2a1f0d9d353 331 Gene3D G3DSA:2.40.100.10 172 311 1.1E-48 T 31-10-2018 IPR029000 Cyclophilin-like domain superfamily TK0332 3ff48a0bd584d754809bd2a1f0d9d353 331 Pfam PF02626 Carboxyltransferase domain, subdomain A and B 24 283 1.5E-81 T 31-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B TK0332 3ff48a0bd584d754809bd2a1f0d9d353 331 SMART SM00797 23 300 2.0E-136 T 31-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B TK0332 3ff48a0bd584d754809bd2a1f0d9d353 331 TIGRFAM TIGR00724 urea_amlyse_rel: biotin-dependent carboxylase uncharacterized domain 1 309 1.2E-104 T 31-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B TK0332 3ff48a0bd584d754809bd2a1f0d9d353 331 SUPERFAMILY SSF50891 173 290 7.59E-10 T 31-10-2018 IPR029000 Cyclophilin-like domain superfamily TK1077 74dd0e48a07172c6fbf5ad333022f65a 215 SUPERFAMILY SSF47973 16 215 6.02E-63 T 31-10-2018 IPR036823 Ribosomal protein S7 domain superfamily TK1077 74dd0e48a07172c6fbf5ad333022f65a 215 Hamap MF_00480_A 30S ribosomal protein S7 [rpsG]. 15 215 37.954 T 31-10-2018 IPR026018 Ribosomal protein S7, archaeal TK1077 74dd0e48a07172c6fbf5ad333022f65a 215 Gene3D G3DSA:1.10.455.10 15 215 2.7E-79 T 31-10-2018 IPR036823 Ribosomal protein S7 domain superfamily TK1077 74dd0e48a07172c6fbf5ad333022f65a 215 Pfam PF00177 Ribosomal protein S7p/S5e 55 215 1.2E-38 T 31-10-2018 IPR023798 Ribosomal protein S7 domain TK1077 74dd0e48a07172c6fbf5ad333022f65a 215 PIRSF PIRSF002122 1 215 6.0E-48 T 31-10-2018 IPR000235 Ribosomal protein S5/S7 GO:0006412 TK1077 74dd0e48a07172c6fbf5ad333022f65a 215 TIGRFAM TIGR01028 uS7_euk_arch: ribosomal protein uS7 14 215 3.4E-89 T 31-10-2018 IPR005716 Ribosomal protein S5/S7, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1763 624bb7ed6efbf3980b5a1588b0b88902 149 SUPERFAMILY SSF88723 5 146 1.71E-26 T 31-10-2018 IPR029060 PIN-like domain superfamily TK1763 624bb7ed6efbf3980b5a1588b0b88902 149 PIRSF PIRSF016154 1 149 2.0E-70 T 31-10-2018 IPR016647 Probable ribonuclease VapC, Thermococci TK1763 624bb7ed6efbf3980b5a1588b0b88902 149 Gene3D G3DSA:3.40.50.1010 1 148 1.5E-37 T 31-10-2018 TK0274 8874884f144ebb1435a87ac05726dd0e 344 SUPERFAMILY SSF53187 5 325 5.19E-46 T 31-10-2018 TK0274 8874884f144ebb1435a87ac05726dd0e 344 Pfam PF01546 Peptidase family M20/M25/M40 62 320 8.5E-22 T 31-10-2018 IPR002933 Peptidase M20 GO:0016787 TK0274 8874884f144ebb1435a87ac05726dd0e 344 Gene3D G3DSA:3.40.630.10 15 312 2.1E-75 T 31-10-2018 TK0274 8874884f144ebb1435a87ac05726dd0e 344 Hamap MF_01120 [LysW]-lysine/[LysW]-ornithine hydrolase [lysK]. 5 323 31.708 T 31-10-2018 IPR010175 [LysW]-lysine/[LysW]-ornithine hydrolase GO:0005737|GO:0008270|GO:0009085|GO:0016811|GO:0050897 TK0274 8874884f144ebb1435a87ac05726dd0e 344 PIRSF PIRSF001123 4 83 9.8E-12 T 31-10-2018 IPR008007 Peptidase M42 TK0274 8874884f144ebb1435a87ac05726dd0e 344 PIRSF PIRSF001123 260 331 6.2 T 31-10-2018 IPR008007 Peptidase M42 TK0274 8874884f144ebb1435a87ac05726dd0e 344 TIGRFAM TIGR01902 dapE-lys-deAc: N-acetyl-ornithine/N-acetyl-lysine deacetylase 9 324 1.4E-118 T 31-10-2018 IPR010175 [LysW]-lysine/[LysW]-ornithine hydrolase GO:0005737|GO:0008270|GO:0009085|GO:0016811|GO:0050897 TK0274 8874884f144ebb1435a87ac05726dd0e 344 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 61 70 - T 31-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 TK0274 8874884f144ebb1435a87ac05726dd0e 344 Gene3D G3DSA:3.30.70.360 151 237 2.1E-75 T 31-10-2018 TK0620 2558b738b30a483fc1ae9a116fdafcd4 104 TIGRFAM TIGR01300 CPA3_mnhG_phaG: monovalent cation/proton antiporter, MnhG/PhaG subunit 6 99 2.7E-31 T 31-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 TK0620 2558b738b30a483fc1ae9a116fdafcd4 104 Pfam PF03334 Na+/H+ antiporter subunit 6 86 7.0E-25 T 31-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 TK1902 2a3d24e76cb2dcb84df10eee95b1f54b 735 PIRSF PIRSF000803 151 732 2.1E-176 T 31-10-2018 IPR011149 DNA polymerase II small subunit, archaeal GO:0003676|GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TK1902 2a3d24e76cb2dcb84df10eee95b1f54b 735 Gene3D G3DSA:3.60.21.50 451 706 1.3E-24 T 31-10-2018 TK1902 2a3d24e76cb2dcb84df10eee95b1f54b 735 Pfam PF04042 DNA polymerase alpha/epsilon subunit B 470 673 5.5E-15 T 31-10-2018 IPR007185 DNA polymerase alpha/epsilon, subunit B GO:0003677|GO:0003887|GO:0006260 TK1902 2a3d24e76cb2dcb84df10eee95b1f54b 735 SUPERFAMILY SSF56300 469 696 4.75E-21 T 31-10-2018 TK1902 2a3d24e76cb2dcb84df10eee95b1f54b 735 Hamap MF_00325 DNA polymerase II small subunit [polB]. 1 725 32.615 T 31-10-2018 IPR011149 DNA polymerase II small subunit, archaeal GO:0003676|GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TK1902 2a3d24e76cb2dcb84df10eee95b1f54b 735 SUPERFAMILY SSF50249 376 436 1.85E-5 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold TK1902 2a3d24e76cb2dcb84df10eee95b1f54b 735 Gene3D G3DSA:1.10.8.800 1 64 5.2E-24 T 31-10-2018 TK0932 336c04661cc1800adafc815506826ec3 136 Pfam PF01797 Transposase IS200 like 12 132 8.3E-39 T 31-10-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 TK0932 336c04661cc1800adafc815506826ec3 136 SMART SM01321 12 132 1.6E-40 T 31-10-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 TK0932 336c04661cc1800adafc815506826ec3 136 SUPERFAMILY SSF143422 4 133 3.14E-42 T 31-10-2018 IPR036515 Transposase IS200-like superfamily GO:0003677|GO:0004803|GO:0006313 TK0932 336c04661cc1800adafc815506826ec3 136 Gene3D G3DSA:3.30.70.1290 1 134 2.1E-40 T 31-10-2018 IPR036515 Transposase IS200-like superfamily GO:0003677|GO:0004803|GO:0006313 TK0197 31d9c6eece800f468a86401debf7fb3a 713 TIGRFAM TIGR01736 FGAM_synth_II: phosphoribosylformylglycinamidine synthase II 2 703 3.1E-295 T 31-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 TK0197 31d9c6eece800f468a86401debf7fb3a 713 SUPERFAMILY SSF56042 545 705 6.73E-35 T 31-10-2018 IPR036676 PurM-like, C-terminal domain superfamily TK0197 31d9c6eece800f468a86401debf7fb3a 713 Pfam PF02769 AIR synthase related protein, C-terminal domain 185 340 7.9E-36 T 31-10-2018 IPR010918 PurM-like, C-terminal domain TK0197 31d9c6eece800f468a86401debf7fb3a 713 Pfam PF02769 AIR synthase related protein, C-terminal domain 548 680 2.5E-18 T 31-10-2018 IPR010918 PurM-like, C-terminal domain TK0197 31d9c6eece800f468a86401debf7fb3a 713 Gene3D G3DSA:3.30.1330.10 27 175 6.0E-123 T 31-10-2018 IPR036921 PurM-like, N-terminal domain superfamily TK0197 31d9c6eece800f468a86401debf7fb3a 713 SUPERFAMILY SSF56042 184 402 1.33E-49 T 31-10-2018 IPR036676 PurM-like, C-terminal domain superfamily TK0197 31d9c6eece800f468a86401debf7fb3a 713 SUPERFAMILY SSF55326 19 178 2.24E-47 T 31-10-2018 IPR036921 PurM-like, N-terminal domain superfamily TK0197 31d9c6eece800f468a86401debf7fb3a 713 Hamap MF_00420 Phosphoribosylformylglycinamidine synthase subunit PurL [purL]. 1 713 257.095 T 31-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 TK0197 31d9c6eece800f468a86401debf7fb3a 713 Pfam PF00586 AIR synthase related protein, N-terminal domain 59 172 5.1E-25 T 31-10-2018 IPR016188 PurM-like, N-terminal domain TK0197 31d9c6eece800f468a86401debf7fb3a 713 Pfam PF00586 AIR synthase related protein, N-terminal domain 417 533 3.4E-20 T 31-10-2018 IPR016188 PurM-like, N-terminal domain TK0197 31d9c6eece800f468a86401debf7fb3a 713 Gene3D G3DSA:3.90.650.10 12 340 6.0E-123 T 31-10-2018 IPR036676 PurM-like, C-terminal domain superfamily TK0197 31d9c6eece800f468a86401debf7fb3a 713 Gene3D G3DSA:3.30.1330.10 366 537 9.7E-55 T 31-10-2018 IPR036921 PurM-like, N-terminal domain superfamily TK0197 31d9c6eece800f468a86401debf7fb3a 713 PIRSF PIRSF001587 1 712 2.3E-289 T 31-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 TK0197 31d9c6eece800f468a86401debf7fb3a 713 Gene3D G3DSA:3.90.650.10 543 709 1.8E-35 T 31-10-2018 IPR036676 PurM-like, C-terminal domain superfamily TK0197 31d9c6eece800f468a86401debf7fb3a 713 SUPERFAMILY SSF55326 378 534 2.62E-49 T 31-10-2018 IPR036921 PurM-like, N-terminal domain superfamily TK2113 fc5f1b6a41a5ab907a23d1b0f7742346 306 Gene3D G3DSA:1.10.10.10 153 199 2.2E-11 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TK2113 fc5f1b6a41a5ab907a23d1b0f7742346 306 Pfam PF13412 Winged helix-turn-helix DNA-binding 154 196 4.1E-11 T 31-10-2018 TK2113 fc5f1b6a41a5ab907a23d1b0f7742346 306 SUPERFAMILY SSF46785 152 200 2.18E-8 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TK1442 a3ba7bc75d2dee6fe984648b436b08ab 442 TIGRFAM TIGR01415 trpB_rel: pyridoxal-phosphate dependent TrpB-like enzyme 10 427 2.0E-220 T 31-10-2018 IPR006316 Tryptophan synthase, beta chain-like GO:0000162|GO:0004834|GO:0030170 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 TK1442 a3ba7bc75d2dee6fe984648b436b08ab 442 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 103 117 - T 31-10-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 TK1442 a3ba7bc75d2dee6fe984648b436b08ab 442 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 75 411 6.0E-45 T 31-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme TK1442 a3ba7bc75d2dee6fe984648b436b08ab 442 PIRSF PIRSF001413 6 430 6.5E-158 T 31-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 TK1442 a3ba7bc75d2dee6fe984648b436b08ab 442 Gene3D G3DSA:3.40.50.1100 11 236 1.4E-179 T 31-10-2018 TK1442 a3ba7bc75d2dee6fe984648b436b08ab 442 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 18 424 42.913 T 31-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 TK1442 a3ba7bc75d2dee6fe984648b436b08ab 442 PIRSF PIRSF500824 1 433 2.0E-215 T 31-10-2018 IPR006316 Tryptophan synthase, beta chain-like GO:0000162|GO:0004834|GO:0030170 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 TK1442 a3ba7bc75d2dee6fe984648b436b08ab 442 SUPERFAMILY SSF53686 24 423 1.44E-111 T 31-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme TK1442 a3ba7bc75d2dee6fe984648b436b08ab 442 Gene3D G3DSA:3.40.50.1100 10 417 1.4E-179 T 31-10-2018 TK0550 75243fb3ce7c236d15b2a1e73f947be5 481 SUPERFAMILY SSF52954 278 402 7.55E-39 T 31-10-2018 TK0550 75243fb3ce7c236d15b2a1e73f947be5 481 Pfam PF03129 Anticodon binding domain 289 383 1.3E-23 T 31-10-2018 IPR004154 Anticodon-binding TK0550 75243fb3ce7c236d15b2a1e73f947be5 481 PRINTS PR01046 Prolyl-tRNA synthetase signature 105 116 1.9E-12 T 31-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 TK0550 75243fb3ce7c236d15b2a1e73f947be5 481 PRINTS PR01046 Prolyl-tRNA synthetase signature 64 82 1.9E-12 T 31-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 TK0550 75243fb3ce7c236d15b2a1e73f947be5 481 PRINTS PR01046 Prolyl-tRNA synthetase signature 145 156 1.9E-12 T 31-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 TK0550 75243fb3ce7c236d15b2a1e73f947be5 481 PRINTS PR01046 Prolyl-tRNA synthetase signature 135 143 1.9E-12 T 31-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 TK0550 75243fb3ce7c236d15b2a1e73f947be5 481 TIGRFAM TIGR00408 proS_fam_I: proline--tRNA ligase 9 481 9.4E-184 T 31-10-2018 IPR004499 Proline-tRNA ligase, class IIa, archaeal-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 TK0550 75243fb3ce7c236d15b2a1e73f947be5 481 SMART SM00946 410 481 9.3E-27 T 31-10-2018 IPR016061 Proline-tRNA ligase, class II, C-terminal GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 TK0550 75243fb3ce7c236d15b2a1e73f947be5 481 Hamap MF_01571 Proline--tRNA ligase [proS]. 5 481 41.787 T 31-10-2018 IPR004499 Proline-tRNA ligase, class IIa, archaeal-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 TK0550 75243fb3ce7c236d15b2a1e73f947be5 481 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 102 271 1.4E-23 T 31-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 TK0550 75243fb3ce7c236d15b2a1e73f947be5 481 Pfam PF09180 Prolyl-tRNA synthetase, C-terminal 411 481 9.5E-18 T 31-10-2018 IPR016061 Proline-tRNA ligase, class II, C-terminal GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 TK0550 75243fb3ce7c236d15b2a1e73f947be5 481 Gene3D G3DSA:3.40.50.800 283 401 7.6E-38 T 31-10-2018 IPR036621 Anticodon-binding domain superfamily TK0550 75243fb3ce7c236d15b2a1e73f947be5 481 SUPERFAMILY SSF55681 10 276 1.3E-75 T 31-10-2018 TK0550 75243fb3ce7c236d15b2a1e73f947be5 481 Gene3D G3DSA:3.30.930.10 11 282 1.4E-85 T 31-10-2018 TK0550 75243fb3ce7c236d15b2a1e73f947be5 481 Gene3D G3DSA:3.30.110.30 404 480 4.5E-20 T 31-10-2018 IPR017449 Prolyl-tRNA synthetase, class II GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 TK0550 75243fb3ce7c236d15b2a1e73f947be5 481 SUPERFAMILY SSF64586 405 481 3.92E-22 T 31-10-2018 IPR017449 Prolyl-tRNA synthetase, class II GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 TK1017 c472ebedf85a31f74d0b9116b1644f29 1189 SUPERFAMILY SSF75553 481 678 7.45E-51 T 31-10-2018 IPR036277 SMCs flexible hinge superfamily GO:0005515|GO:0005524|GO:0005694|GO:0051276 TK1017 c472ebedf85a31f74d0b9116b1644f29 1189 SUPERFAMILY SSF52540 2 1170 1.5E-57 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK1017 c472ebedf85a31f74d0b9116b1644f29 1189 Hamap MF_01894 Chromosome partition protein Smc [smc]. 3 1164 21.612 T 31-10-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 TK1017 c472ebedf85a31f74d0b9116b1644f29 1189 SUPERFAMILY SSF58104 690 916 1.52E-5 T 31-10-2018 TK1017 c472ebedf85a31f74d0b9116b1644f29 1189 TIGRFAM TIGR02169 SMC_prok_A: chromosome segregation protein SMC 4 1162 0.0 T 31-10-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 TK1017 c472ebedf85a31f74d0b9116b1644f29 1189 Gene3D G3DSA:1.20.1060.20 508 663 1.7E-45 T 31-10-2018 TK1017 c472ebedf85a31f74d0b9116b1644f29 1189 Gene3D G3DSA:3.40.50.300 3 235 1.4E-60 T 31-10-2018 TK1017 c472ebedf85a31f74d0b9116b1644f29 1189 Pfam PF02463 RecF/RecN/SMC N terminal domain 4 1155 2.1E-73 T 31-10-2018 IPR003395 RecF/RecN/SMC, N-terminal TK1017 c472ebedf85a31f74d0b9116b1644f29 1189 Gene3D G3DSA:1.20.5.340 669 771 2.5E-5 T 31-10-2018 TK1017 c472ebedf85a31f74d0b9116b1644f29 1189 Gene3D G3DSA:1.20.5.340 358 498 1.6E-5 T 31-10-2018 TK1017 c472ebedf85a31f74d0b9116b1644f29 1189 Gene3D G3DSA:1.20.5.340 772 877 1.1E-8 T 31-10-2018 TK1017 c472ebedf85a31f74d0b9116b1644f29 1189 TIGRFAM TIGR02168 SMC_prok_B: chromosome segregation protein SMC 4 1162 2.2E-242 T 31-10-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 TK1017 c472ebedf85a31f74d0b9116b1644f29 1189 Gene3D G3DSA:3.30.70.1620 582 659 1.7E-45 T 31-10-2018 TK1017 c472ebedf85a31f74d0b9116b1644f29 1189 Pfam PF06470 SMC proteins Flexible Hinge Domain 521 632 6.0E-34 T 31-10-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 TK1017 c472ebedf85a31f74d0b9116b1644f29 1189 SUPERFAMILY SSF57997 380 513 1.18E-7 T 31-10-2018 TK1017 c472ebedf85a31f74d0b9116b1644f29 1189 Gene3D G3DSA:3.40.50.300 1011 1182 8.1E-61 T 31-10-2018 TK1017 c472ebedf85a31f74d0b9116b1644f29 1189 SMART SM00968 521 633 2.1E-43 T 31-10-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 TK1017 c472ebedf85a31f74d0b9116b1644f29 1189 PIRSF PIRSF005719 2 1169 1.1E-280 T 31-10-2018 IPR024704 Structural maintenance of chromosomes protein TK1452 27b2089393e388d87242de353ca70589 523 Gene3D G3DSA:1.20.1560.10 4 311 2.2E-26 T 31-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TK1452 27b2089393e388d87242de353ca70589 523 SUPERFAMILY SSF52540 323 522 2.05E-48 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK1452 27b2089393e388d87242de353ca70589 523 ProSitePatterns PS00211 ABC transporters family signature. 445 459 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TK1452 27b2089393e388d87242de353ca70589 523 Pfam PF00005 ABC transporter 334 472 2.4E-30 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TK1452 27b2089393e388d87242de353ca70589 523 Gene3D G3DSA:3.40.50.300 318 523 5.9E-56 T 31-10-2018 TK1452 27b2089393e388d87242de353ca70589 523 SUPERFAMILY SSF90123 11 301 1.29E-31 T 31-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TK1452 27b2089393e388d87242de353ca70589 523 SMART SM00382 343 517 4.9E-17 T 31-10-2018 IPR003593 AAA+ ATPase domain TK1452 27b2089393e388d87242de353ca70589 523 Pfam PF00664 ABC transporter transmembrane region 48 206 5.5E-13 T 31-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 TK0278 a8be65e32c58f0f121bcca045e31d318 273 Gene3D G3DSA:3.30.1490.20 97 165 2.4E-29 T 31-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 TK0278 a8be65e32c58f0f121bcca045e31d318 273 Gene3D G3DSA:3.40.50.20 1 96 4.4E-38 T 31-10-2018 TK0278 a8be65e32c58f0f121bcca045e31d318 273 TIGRFAM TIGR02144 LysX_arch: lysine biosynthesis enzyme LysX 3 272 1.6E-106 T 31-10-2018 IPR011870 Lysine biosynthesis enzyme LysX GO:0003824|GO:0005524|GO:0009085 TK0278 a8be65e32c58f0f121bcca045e31d318 273 TIGRFAM TIGR00768 rimK_fam: alpha-L-glutamate ligase, RimK family 3 267 6.0E-85 T 31-10-2018 IPR004666 Ribosomal S6 modification enzyme RimK/Lysine biosynthesis enzyme LysX GO:0006464 Reactome: R-HSA-70614 TK0278 a8be65e32c58f0f121bcca045e31d318 273 SUPERFAMILY SSF52440 2 82 9.78E-21 T 31-10-2018 IPR016185 Pre-ATP-grasp domain superfamily TK0278 a8be65e32c58f0f121bcca045e31d318 273 SUPERFAMILY SSF56059 81 269 1.25E-34 T 31-10-2018 TK0278 a8be65e32c58f0f121bcca045e31d318 273 Pfam PF08443 RimK-like ATP-grasp domain 113 266 5.6E-21 T 31-10-2018 IPR013651 ATP-grasp fold, RimK-type Reactome: R-HSA-70614 TK0278 a8be65e32c58f0f121bcca045e31d318 273 Gene3D G3DSA:3.30.470.80 166 273 3.7E-40 T 31-10-2018 TK0282 584f65997eb93b222b05f3e2978baf7e 380 Gene3D G3DSA:3.30.499.10 235 378 1.7E-54 T 31-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 TK0282 584f65997eb93b222b05f3e2978baf7e 380 Pfam PF00330 Aconitase family (aconitate hydratase) 219 371 5.8E-34 T 31-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TK0282 584f65997eb93b222b05f3e2978baf7e 380 Pfam PF00330 Aconitase family (aconitate hydratase) 73 210 2.1E-29 T 31-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TK0282 584f65997eb93b222b05f3e2978baf7e 380 TIGRFAM TIGR02086 IPMI_arch: 3-isopropylmalate dehydratase, large subunit 2 377 3.4E-154 T 31-10-2018 IPR011826 Homoaconitase/3-isopropylmalate dehydratase, large subunit, prokaryotic GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 TK0282 584f65997eb93b222b05f3e2978baf7e 380 ProSitePatterns PS00450 Aconitase family signature 1. 254 270 - T 31-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 TK0282 584f65997eb93b222b05f3e2978baf7e 380 PRINTS PR00415 Aconitase family signature 99 112 9.0E-6 T 31-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TK0282 584f65997eb93b222b05f3e2978baf7e 380 PRINTS PR00415 Aconitase family signature 113 128 9.0E-6 T 31-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TK0282 584f65997eb93b222b05f3e2978baf7e 380 PRINTS PR00415 Aconitase family signature 186 199 9.0E-6 T 31-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TK0282 584f65997eb93b222b05f3e2978baf7e 380 ProSitePatterns PS01244 Aconitase family signature 2. 312 325 - T 31-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 TK0282 584f65997eb93b222b05f3e2978baf7e 380 Hamap MF_01027 3-isopropylmalate dehydratase large subunit [leuC]. 1 379 41.938 T 31-10-2018 IPR011826 Homoaconitase/3-isopropylmalate dehydratase, large subunit, prokaryotic GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 TK0282 584f65997eb93b222b05f3e2978baf7e 380 SUPERFAMILY SSF53732 10 376 9.16E-103 T 31-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 TK0282 584f65997eb93b222b05f3e2978baf7e 380 Gene3D G3DSA:3.30.499.20 2 219 4.5E-55 T 31-10-2018 TK1613 2e4a84ac29dc1d5399a9e219dd977d87 600 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 158 329 1.0E-50 T 31-10-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TK1613 2e4a84ac29dc1d5399a9e219dd977d87 600 Gene3D G3DSA:3.40.50.11540 163 341 3.7E-84 T 31-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TK1613 2e4a84ac29dc1d5399a9e219dd977d87 600 Gene3D G3DSA:3.40.30.10 5 97 5.7E-20 T 31-10-2018 TK1613 2e4a84ac29dc1d5399a9e219dd977d87 600 SUPERFAMILY SSF140490 435 533 1.28E-36 T 31-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TK1613 2e4a84ac29dc1d5399a9e219dd977d87 600 Pfam PF10531 SLBB domain 353 401 6.1E-9 T 31-10-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TK1613 2e4a84ac29dc1d5399a9e219dd977d87 600 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 547 558 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TK1613 2e4a84ac29dc1d5399a9e219dd977d87 600 SUPERFAMILY SSF142019 112 350 1.96E-97 T 31-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TK1613 2e4a84ac29dc1d5399a9e219dd977d87 600 Gene3D G3DSA:1.20.1440.230 437 536 4.8E-34 T 31-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TK1613 2e4a84ac29dc1d5399a9e219dd977d87 600 Gene3D G3DSA:3.10.20.600 342 436 5.1E-33 T 31-10-2018 TK1613 2e4a84ac29dc1d5399a9e219dd977d87 600 SUPERFAMILY SSF52833 7 98 3.8E-19 T 31-10-2018 IPR036249 Thioredoxin-like superfamily TK1613 2e4a84ac29dc1d5399a9e219dd977d87 600 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 440 524 2.1E-32 T 31-10-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TK1613 2e4a84ac29dc1d5399a9e219dd977d87 600 SUPERFAMILY SSF54862 540 596 2.18E-15 T 31-10-2018 TK1613 2e4a84ac29dc1d5399a9e219dd977d87 600 Gene3D G3DSA:3.30.70.20 539 594 1.9E-13 T 31-10-2018 TK1613 2e4a84ac29dc1d5399a9e219dd977d87 600 Pfam PF00037 4Fe-4S binding domain 540 563 1.5E-6 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TK1613 2e4a84ac29dc1d5399a9e219dd977d87 600 Pfam PF00037 4Fe-4S binding domain 571 593 1.2E-7 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TK1613 2e4a84ac29dc1d5399a9e219dd977d87 600 SMART SM00928 439 484 1.6E-24 T 31-10-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TK1613 2e4a84ac29dc1d5399a9e219dd977d87 600 SUPERFAMILY SSF142984 351 434 1.83E-25 T 31-10-2018 TK0671 993fc868e418afb3836340781336658c 337 TIGRFAM TIGR00321 dhys: deoxyhypusine synthase 20 335 5.4E-122 T 31-10-2018 IPR002773 Deoxyhypusine synthase GO:0008612 Reactome: R-HSA-204626 TK0671 993fc868e418afb3836340781336658c 337 SUPERFAMILY SSF52467 5 334 1.01E-115 T 31-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily TK0671 993fc868e418afb3836340781336658c 337 Pfam PF01916 Deoxyhypusine synthase 34 331 1.9E-112 T 31-10-2018 IPR002773 Deoxyhypusine synthase GO:0008612 Reactome: R-HSA-204626 TK0671 993fc868e418afb3836340781336658c 337 Hamap MF_00153 Probable deoxyhypusine synthase [dys]. 31 334 42.473 T 31-10-2018 IPR022899 Deoxyhypusine synthase, putative, archaeal GO:0034038 TK0671 993fc868e418afb3836340781336658c 337 Gene3D G3DSA:3.40.910.10 2 337 1.1E-145 T 31-10-2018 IPR036982 Deoxyhypusine synthase superfamily GO:0008612 Reactome: R-HSA-204626 TK1274 22a7b6ca94d40b5e9217a71430f729a3 888 Gene3D G3DSA:3.90.740.10 170 337 7.4E-243 T 31-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 TK1274 22a7b6ca94d40b5e9217a71430f729a3 888 SUPERFAMILY SSF47323 586 825 1.79E-62 T 31-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 TK1274 22a7b6ca94d40b5e9217a71430f729a3 888 SUPERFAMILY SSF52374 3 579 2.6E-127 T 31-10-2018 TK1274 22a7b6ca94d40b5e9217a71430f729a3 888 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 14 570 5.3E-140 T 31-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 TK1274 22a7b6ca94d40b5e9217a71430f729a3 888 Pfam PF08264 Anticodon-binding domain of tRNA 614 762 5.4E-39 T 31-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 TK1274 22a7b6ca94d40b5e9217a71430f729a3 888 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 43 54 - T 31-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 TK1274 22a7b6ca94d40b5e9217a71430f729a3 888 TIGRFAM TIGR00422 valS: valine--tRNA ligase 3 864 9.5E-273 T 31-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 TK1274 22a7b6ca94d40b5e9217a71430f729a3 888 Hamap MF_02005 Valine--tRNA ligase [valS]. 2 793 28.927 T 31-10-2018 IPR022874 Valine-tRNA ligase, type 2 GO:0004832 KEGG: 00970+6.1.1.9 TK1274 22a7b6ca94d40b5e9217a71430f729a3 888 Gene3D G3DSA:3.40.50.620 22 535 7.4E-243 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TK1274 22a7b6ca94d40b5e9217a71430f729a3 888 Gene3D G3DSA:1.10.730.10 2 750 7.4E-243 T 31-10-2018 TK1274 22a7b6ca94d40b5e9217a71430f729a3 888 SUPERFAMILY SSF50677 187 335 1.7E-51 T 31-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 TK1274 22a7b6ca94d40b5e9217a71430f729a3 888 PRINTS PR00986 Valyl-tRNA synthetase signature 36 47 2.3E-19 T 31-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 TK1274 22a7b6ca94d40b5e9217a71430f729a3 888 PRINTS PR00986 Valyl-tRNA synthetase signature 343 356 2.3E-19 T 31-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 TK1274 22a7b6ca94d40b5e9217a71430f729a3 888 PRINTS PR00986 Valyl-tRNA synthetase signature 448 469 2.3E-19 T 31-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 TK1274 22a7b6ca94d40b5e9217a71430f729a3 888 PRINTS PR00986 Valyl-tRNA synthetase signature 486 504 2.3E-19 T 31-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 TK1274 22a7b6ca94d40b5e9217a71430f729a3 888 PRINTS PR00986 Valyl-tRNA synthetase signature 225 242 2.3E-19 T 31-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 TK1186 979aaa28c9cc31b463ba4fc796282170 391 SUPERFAMILY SSF54631 128 261 6.33E-35 T 31-10-2018 TK1186 979aaa28c9cc31b463ba4fc796282170 391 Pfam PF00571 CBS domain 211 261 6.0E-13 T 31-10-2018 IPR000644 CBS domain TK1186 979aaa28c9cc31b463ba4fc796282170 391 Pfam PF00571 CBS domain 69 122 3.5E-5 T 31-10-2018 IPR000644 CBS domain TK1186 979aaa28c9cc31b463ba4fc796282170 391 Pfam PF00571 CBS domain 132 183 1.9E-16 T 31-10-2018 IPR000644 CBS domain TK1186 979aaa28c9cc31b463ba4fc796282170 391 Gene3D G3DSA:3.10.580.10 130 274 1.6E-36 T 31-10-2018 TK1186 979aaa28c9cc31b463ba4fc796282170 391 PIRSF PIRSF036983 2 391 4.4E-146 T 31-10-2018 IPR014651 Uncharacterised conserved protein, 2xCBS, MJ1404 type TK1186 979aaa28c9cc31b463ba4fc796282170 391 SMART SM00116 139 187 3.5E-11 T 31-10-2018 IPR000644 CBS domain TK1186 979aaa28c9cc31b463ba4fc796282170 391 SMART SM00116 75 123 1.3 T 31-10-2018 IPR000644 CBS domain TK1186 979aaa28c9cc31b463ba4fc796282170 391 SMART SM00116 217 265 1.3E-9 T 31-10-2018 IPR000644 CBS domain TK1186 979aaa28c9cc31b463ba4fc796282170 391 Gene3D G3DSA:3.10.580.10 1 129 7.7E-18 T 31-10-2018 TK1186 979aaa28c9cc31b463ba4fc796282170 391 SUPERFAMILY SSF54631 4 122 1.2E-17 T 31-10-2018 TK2107 fe3d2aa318029d42bc642bd6affe072d 168 SUPERFAMILY SSF46785 5 100 1.55E-24 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TK2107 fe3d2aa318029d42bc642bd6affe072d 168 Gene3D G3DSA:1.10.10.10 3 114 2.9E-20 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TK2107 fe3d2aa318029d42bc642bd6affe072d 168 Pfam PF03551 Transcriptional regulator PadR-like family 20 93 8.6E-18 T 31-10-2018 IPR005149 Transcription regulator PadR, N-terminal TK0258 ffcfbf573a89c93e988e55cd87fef87b 251 Pfam PF00290 Tryptophan synthase alpha chain 4 242 9.4E-79 T 31-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 TK0258 ffcfbf573a89c93e988e55cd87fef87b 251 ProSitePatterns PS00167 Tryptophan synthase alpha chain signature. 35 48 - T 31-10-2018 IPR018204 Tryptophan synthase, alpha chain, active site GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 TK0258 ffcfbf573a89c93e988e55cd87fef87b 251 Gene3D G3DSA:3.20.20.70 1 247 7.4E-99 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TK0258 ffcfbf573a89c93e988e55cd87fef87b 251 SUPERFAMILY SSF51366 4 239 2.83E-81 T 31-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 TK0258 ffcfbf573a89c93e988e55cd87fef87b 251 Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. 2 247 37.386 T 31-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 TK0258 ffcfbf573a89c93e988e55cd87fef87b 251 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 4 242 1.6E-85 T 31-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 TK0682 6200a0588a80a09381a5459770705fa0 576 SUPERFAMILY SSF52540 369 555 9.25E-18 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK0682 6200a0588a80a09381a5459770705fa0 576 SMART SM00534 386 574 4.9E-30 T 31-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 TK0682 6200a0588a80a09381a5459770705fa0 576 Pfam PF00488 MutS domain V 389 434 1.5E-7 T 31-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 TK0682 6200a0588a80a09381a5459770705fa0 576 Hamap MF_00971 DNA-binding protein MutS2 [mutS2]. 3 573 25.607 T 31-10-2018 IPR012401 DNA-binding protein MutS2, archaea TK0682 6200a0588a80a09381a5459770705fa0 576 Gene3D G3DSA:3.40.50.300 338 528 1.8E-21 T 31-10-2018 TK0682 6200a0588a80a09381a5459770705fa0 576 PIRSF PIRSF029254 1 575 2.9E-195 T 31-10-2018 IPR012401 DNA-binding protein MutS2, archaea TK1413 caea1f81279d65b1d317ec1262420ff1 67 Gene3D G3DSA:1.10.20.10 1 67 1.7E-24 T 31-10-2018 IPR009072 Histone-fold GO:0046982 TK1413 caea1f81279d65b1d317ec1262420ff1 67 SUPERFAMILY SSF47113 3 66 4.48E-20 T 31-10-2018 IPR009072 Histone-fold GO:0046982 TK1413 caea1f81279d65b1d317ec1262420ff1 67 Pfam PF00808 Histone-like transcription factor (CBF/NF-Y) and archaeal histone 2 65 5.6E-21 T 31-10-2018 IPR003958 Transcription factor CBF/NF-Y/archaeal histone domain TK1383 ad0ce1f8a47296c6641dc0c20009d1e8 230 Pfam PF13419 Haloacid dehalogenase-like hydrolase 3 135 3.2E-12 T 31-10-2018 TK1383 ad0ce1f8a47296c6641dc0c20009d1e8 230 SUPERFAMILY SSF56784 1 184 3.86E-19 T 31-10-2018 IPR036412 HAD-like superfamily TK1383 ad0ce1f8a47296c6641dc0c20009d1e8 230 Gene3D G3DSA:1.10.150.240 13 85 2.4E-12 T 31-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 TK1383 ad0ce1f8a47296c6641dc0c20009d1e8 230 Gene3D G3DSA:3.40.50.1000 5 135 2.4E-12 T 31-10-2018 IPR023214 HAD superfamily TK0363 592ebf5050c0f02cf768206cbd9a140b 284 Gene3D G3DSA:3.20.20.60 2 273 3.5E-110 T 31-10-2018 TK0363 592ebf5050c0f02cf768206cbd9a140b 284 Pfam PF02548 Ketopantoate hydroxymethyltransferase 4 257 2.4E-107 T 31-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 TK0363 592ebf5050c0f02cf768206cbd9a140b 284 Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. 4 262 41.399 T 31-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 TK0363 592ebf5050c0f02cf768206cbd9a140b 284 SUPERFAMILY SSF51621 4 262 6.67E-103 T 31-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 TK0363 592ebf5050c0f02cf768206cbd9a140b 284 TIGRFAM TIGR00222 panB: 3-methyl-2-oxobutanoate hydroxymethyltransferase 11 262 2.5E-90 T 31-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 TK0363 592ebf5050c0f02cf768206cbd9a140b 284 PIRSF PIRSF000388 1 265 6.0E-105 T 31-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 TK1785 d57ea3c7c7753ac3d2b8cb2f8cf27ee7 396 Gene3D G3DSA:3.40.50.150 179 396 5.0E-71 T 31-10-2018 TK1785 d57ea3c7c7753ac3d2b8cb2f8cf27ee7 396 Gene3D G3DSA:3.30.750.80 72 178 4.1E-37 T 31-10-2018 TK1785 d57ea3c7c7753ac3d2b8cb2f8cf27ee7 396 Gene3D G3DSA:2.30.130.10 1 71 4.4E-21 T 31-10-2018 IPR036974 PUA domain superfamily GO:0003723 TK1785 d57ea3c7c7753ac3d2b8cb2f8cf27ee7 396 Pfam PF10672 S-adenosylmethionine-dependent methyltransferase 169 332 2.9E-20 T 31-10-2018 IPR019614 S-adenosylmethionine-dependent methyltransferase GO:0008168 TK1785 d57ea3c7c7753ac3d2b8cb2f8cf27ee7 396 SUPERFAMILY SSF88697 1 70 9.45E-17 T 31-10-2018 IPR015947 PUA-like superfamily TK1785 d57ea3c7c7753ac3d2b8cb2f8cf27ee7 396 Pfam PF01472 PUA domain 3 75 1.7E-14 T 31-10-2018 IPR002478 PUA domain GO:0003723 TK1785 d57ea3c7c7753ac3d2b8cb2f8cf27ee7 396 SMART SM00359 2 87 1.6E-23 T 31-10-2018 IPR002478 PUA domain GO:0003723 TK1785 d57ea3c7c7753ac3d2b8cb2f8cf27ee7 396 SUPERFAMILY SSF53335 78 389 7.79E-68 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TK1946 b18877b8f857d5cb0f447ca6a7f22872 410 Hamap MF_00119 Translation initiation factor 2 subunit gamma [eif2g]. 4 409 61.593 T 31-10-2018 IPR022424 Translation initiation factor 2, gamma subunit TK1946 b18877b8f857d5cb0f447ca6a7f22872 410 SUPERFAMILY SSF52540 4 209 1.54E-54 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK1946 b18877b8f857d5cb0f447ca6a7f22872 410 Gene3D G3DSA:2.40.30.10 319 410 5.1E-34 T 31-10-2018 TK1946 b18877b8f857d5cb0f447ca6a7f22872 410 SUPERFAMILY SSF50465 317 409 5.76E-33 T 31-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal TK1946 b18877b8f857d5cb0f447ca6a7f22872 410 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 10 193 2.2E-18 T 31-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 TK1946 b18877b8f857d5cb0f447ca6a7f22872 410 Gene3D G3DSA:3.40.50.300 3 203 4.4E-69 T 31-10-2018 TK1946 b18877b8f857d5cb0f447ca6a7f22872 410 PRINTS PR00315 GTP-binding elongation factor signature 13 26 4.1E-14 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TK1946 b18877b8f857d5cb0f447ca6a7f22872 410 PRINTS PR00315 GTP-binding elongation factor signature 140 149 4.1E-14 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TK1946 b18877b8f857d5cb0f447ca6a7f22872 410 PRINTS PR00315 GTP-binding elongation factor signature 103 114 4.1E-14 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TK1946 b18877b8f857d5cb0f447ca6a7f22872 410 PRINTS PR00315 GTP-binding elongation factor signature 87 97 4.1E-14 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TK1946 b18877b8f857d5cb0f447ca6a7f22872 410 Gene3D G3DSA:2.40.30.10 204 318 1.7E-46 T 31-10-2018 TK1946 b18877b8f857d5cb0f447ca6a7f22872 410 SUPERFAMILY SSF50447 203 316 2.08E-38 T 31-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily TK1946 b18877b8f857d5cb0f447ca6a7f22872 410 Pfam PF09173 Initiation factor eIF2 gamma, C terminal 324 408 4.5E-31 T 31-10-2018 IPR015256 Translation initiation factor 2, gamma subunit, C-terminal TK1946 b18877b8f857d5cb0f447ca6a7f22872 410 Pfam PF00009 Elongation factor Tu GTP binding domain 12 199 8.0E-37 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TK1946 b18877b8f857d5cb0f447ca6a7f22872 410 TIGRFAM TIGR03680 eif2g_arch: translation initiation factor 2, gamma subunit 8 409 5.5E-208 T 31-10-2018 IPR022424 Translation initiation factor 2, gamma subunit TK1946 b18877b8f857d5cb0f447ca6a7f22872 410 Pfam PF03144 Elongation factor Tu domain 2 231 311 7.7E-11 T 31-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 TK1899 59e002d962213cacd3a18c31f78011e2 836 Gene3D G3DSA:1.10.150.20 41 103 1.4E-24 T 31-10-2018 TK1899 59e002d962213cacd3a18c31f78011e2 836 Pfam PF14890 Intein splicing domain 184 631 2.4E-25 T 31-10-2018 TK1899 59e002d962213cacd3a18c31f78011e2 836 Gene3D G3DSA:3.10.28.10 283 439 3.9E-28 T 31-10-2018 IPR027434 Homing endonuclease TK1899 59e002d962213cacd3a18c31f78011e2 836 Pfam PF08423 Rad51 102 150 1.8E-13 T 31-10-2018 IPR013632 DNA recombination and repair protein Rad51-like, C-terminal Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579 TK1899 59e002d962213cacd3a18c31f78011e2 836 Pfam PF08423 Rad51 632 836 3.9E-70 T 31-10-2018 IPR013632 DNA recombination and repair protein Rad51-like, C-terminal Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579 TK1899 59e002d962213cacd3a18c31f78011e2 836 Pfam PF14520 Helix-hairpin-helix domain 41 95 2.0E-11 T 31-10-2018 TK1899 59e002d962213cacd3a18c31f78011e2 836 SUPERFAMILY SSF52540 81 149 8.73E-8 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK1899 59e002d962213cacd3a18c31f78011e2 836 SMART SM00305 590 637 1.0E-12 T 31-10-2018 IPR003586 Hint domain C-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TK1899 59e002d962213cacd3a18c31f78011e2 836 SUPERFAMILY SSF51294 150 632 1.04E-40 T 31-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TK1899 59e002d962213cacd3a18c31f78011e2 836 Gene3D G3DSA:2.170.16.10 561 632 4.8E-17 T 31-10-2018 TK1899 59e002d962213cacd3a18c31f78011e2 836 Gene3D G3DSA:2.170.16.10 149 282 2.1E-38 T 31-10-2018 TK1899 59e002d962213cacd3a18c31f78011e2 836 TIGRFAM TIGR02236 recomb_radA: DNA repair and recombination protein RadA 631 836 9.4E-109 T 31-10-2018 IPR011938 DNA recombination/repair protein RadA GO:0003684|GO:0005524|GO:0006281|GO:0006310|GO:0008094 TK1899 59e002d962213cacd3a18c31f78011e2 836 SMART SM00278 40 59 0.018 T 31-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 TK1899 59e002d962213cacd3a18c31f78011e2 836 SMART SM00278 73 92 160.0 T 31-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 TK1899 59e002d962213cacd3a18c31f78011e2 836 PRINTS PR00379 Intein signature 233 246 7.6E-13 T 31-10-2018 IPR006142 Intein GO:0016539 TK1899 59e002d962213cacd3a18c31f78011e2 836 PRINTS PR00379 Intein signature 371 383 7.6E-13 T 31-10-2018 IPR006142 Intein GO:0016539 TK1899 59e002d962213cacd3a18c31f78011e2 836 PRINTS PR00379 Intein signature 607 624 7.6E-13 T 31-10-2018 IPR006142 Intein GO:0016539 TK1899 59e002d962213cacd3a18c31f78011e2 836 PRINTS PR00379 Intein signature 626 635 7.6E-13 T 31-10-2018 IPR006142 Intein GO:0016539 TK1899 59e002d962213cacd3a18c31f78011e2 836 PRINTS PR00379 Intein signature 282 294 7.6E-13 T 31-10-2018 IPR006142 Intein GO:0016539 TK1899 59e002d962213cacd3a18c31f78011e2 836 Gene3D G3DSA:3.40.50.300 104 148 3.4E-11 T 31-10-2018 TK1899 59e002d962213cacd3a18c31f78011e2 836 TIGRFAM TIGR01445 intein_Nterm: intein N-terminal splicing region 150 246 2.5E-11 T 31-10-2018 IPR006141 Intein N-terminal splicing region GO:0016539 Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TK1899 59e002d962213cacd3a18c31f78011e2 836 Hamap MF_00348 DNA repair and recombination protein RadA [radA]. 39 836 70.781 T 31-10-2018 IPR011938 DNA recombination/repair protein RadA GO:0003684|GO:0005524|GO:0006281|GO:0006310|GO:0008094 TK1899 59e002d962213cacd3a18c31f78011e2 836 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 609 632 1.2E-5 T 31-10-2018 IPR030934 Intein C-terminal splicing region TK1899 59e002d962213cacd3a18c31f78011e2 836 SUPERFAMILY SSF55608 355 436 7.65E-18 T 31-10-2018 IPR027434 Homing endonuclease TK1899 59e002d962213cacd3a18c31f78011e2 836 Gene3D G3DSA:3.40.50.300 633 836 5.1E-63 T 31-10-2018 TK1899 59e002d962213cacd3a18c31f78011e2 836 SUPERFAMILY SSF52540 632 835 1.06E-42 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK1899 59e002d962213cacd3a18c31f78011e2 836 SMART SM00306 148 269 9.4E-22 T 31-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TK1899 59e002d962213cacd3a18c31f78011e2 836 SUPERFAMILY SSF47794 38 98 4.55E-13 T 31-10-2018 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 TK1899 59e002d962213cacd3a18c31f78011e2 836 Pfam PF14528 LAGLIDADG-like domain 370 438 5.1E-12 T 31-10-2018 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 TK1163 deb3b57b77325ed94d5a6ce67ccd22b5 159 SUPERFAMILY SSF159902 1 155 7.19E-76 T 31-10-2018 TK1163 deb3b57b77325ed94d5a6ce67ccd22b5 159 Pfam PF09638 Ph1570 protein 1 155 5.5E-94 T 31-10-2018 IPR023110 PH1570-like domain TK1163 deb3b57b77325ed94d5a6ce67ccd22b5 159 Gene3D G3DSA:3.40.1600.10 1 156 1.7E-74 T 31-10-2018 IPR036807 PH1570-like superfamily TK2066 5ddc77518a092c1c1b1b2d1ad566c139 148 Pfam PF01750 Hydrogenase maturation protease 28 144 1.2E-21 T 31-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 TK2066 5ddc77518a092c1c1b1b2d1ad566c139 148 Gene3D G3DSA:3.40.50.1450 1 148 2.8E-36 T 31-10-2018 IPR023430 Peptidase HybD-like domain superfamily TK2066 5ddc77518a092c1c1b1b2d1ad566c139 148 TIGRFAM TIGR00072 hydrog_prot: hydrogenase maturation protease 4 145 8.3E-32 T 31-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 TK2066 5ddc77518a092c1c1b1b2d1ad566c139 148 PRINTS PR00446 Hydrogen uptake protein signature 51 61 5.1E-7 T 31-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 TK2066 5ddc77518a092c1c1b1b2d1ad566c139 148 PRINTS PR00446 Hydrogen uptake protein signature 3 15 5.1E-7 T 31-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 TK2066 5ddc77518a092c1c1b1b2d1ad566c139 148 PRINTS PR00446 Hydrogen uptake protein signature 63 79 5.1E-7 T 31-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 TK2066 5ddc77518a092c1c1b1b2d1ad566c139 148 PRINTS PR00446 Hydrogen uptake protein signature 15 26 5.1E-7 T 31-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 TK2066 5ddc77518a092c1c1b1b2d1ad566c139 148 SUPERFAMILY SSF53163 2 146 7.59E-31 T 31-10-2018 IPR023430 Peptidase HybD-like domain superfamily TK1447 f43c625389263f1a5a8cfad41b7199f5 309 SUPERFAMILY SSF51726 6 303 2.62E-47 T 31-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 TK1447 f43c625389263f1a5a8cfad41b7199f5 309 Gene3D G3DSA:3.20.20.210 5 307 9.6E-48 T 31-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 TK1447 f43c625389263f1a5a8cfad41b7199f5 309 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 5 297 1.4E-9 T 31-10-2018 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 TK0327 3c43bcc7d71d6b6c30d7941bcfa7fe61 218 SUPERFAMILY SSF89550 6 214 4.58E-41 T 31-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 TK0327 3c43bcc7d71d6b6c30d7941bcfa7fe61 218 Gene3D G3DSA:3.20.20.140 2 217 3.0E-49 T 31-10-2018 TK0327 3c43bcc7d71d6b6c30d7941bcfa7fe61 218 Pfam PF02811 PHP domain 7 88 1.6E-8 T 31-10-2018 IPR004013 PHP domain GO:0003824 TK0327 3c43bcc7d71d6b6c30d7941bcfa7fe61 218 SMART SM00481 6 78 6.7E-14 T 31-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal TK1282 650c1000a6fbfb95e0b4212db45e65a4 400 SMART SM00852 184 321 1.1E-38 T 31-10-2018 IPR001453 MoaB/Mog domain TK1282 650c1000a6fbfb95e0b4212db45e65a4 400 Gene3D G3DSA:3.40.980.10 179 320 3.4E-115 T 31-10-2018 IPR036425 MoaB/Mog-like domain superfamily TK1282 650c1000a6fbfb95e0b4212db45e65a4 400 Pfam PF00994 Probable molybdopterin binding domain 184 320 3.9E-24 T 31-10-2018 IPR001453 MoaB/Mog domain TK1282 650c1000a6fbfb95e0b4212db45e65a4 400 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 180 317 1.5E-32 T 31-10-2018 IPR001453 MoaB/Mog domain TK1282 650c1000a6fbfb95e0b4212db45e65a4 400 SUPERFAMILY SSF63882 7 180 3.79E-58 T 31-10-2018 IPR036135 MoeA, N-terminal and linker domain superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TK1282 650c1000a6fbfb95e0b4212db45e65a4 400 SUPERFAMILY SSF53218 181 325 3.66E-42 T 31-10-2018 IPR036425 MoaB/Mog-like domain superfamily TK1282 650c1000a6fbfb95e0b4212db45e65a4 400 Pfam PF03453 MoeA N-terminal region (domain I and II) 8 171 1.3E-44 T 31-10-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TK1282 650c1000a6fbfb95e0b4212db45e65a4 400 SUPERFAMILY SSF63867 331 399 1.83E-18 T 31-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TK1282 650c1000a6fbfb95e0b4212db45e65a4 400 Gene3D G3DSA:3.90.105.10 26 178 3.4E-115 T 31-10-2018 TK1282 650c1000a6fbfb95e0b4212db45e65a4 400 Gene3D G3DSA:2.170.190.11 49 145 3.4E-115 T 31-10-2018 TK1282 650c1000a6fbfb95e0b4212db45e65a4 400 Pfam PF03454 MoeA C-terminal region (domain IV) 335 399 1.8E-18 T 31-10-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TK1282 650c1000a6fbfb95e0b4212db45e65a4 400 Gene3D G3DSA:2.40.340.10 329 400 5.7E-26 T 31-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TK2106 ebe4c7fdaee3a32108b0ed508a7593ee 430 Pfam PF03952 Enolase, N-terminal domain 7 135 1.9E-60 T 31-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TK2106 ebe4c7fdaee3a32108b0ed508a7593ee 430 Pfam PF00113 Enolase, C-terminal TIM barrel domain 141 427 1.6E-130 T 31-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TK2106 ebe4c7fdaee3a32108b0ed508a7593ee 430 PRINTS PR00148 Enolase signature 162 175 2.2E-50 T 31-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TK2106 ebe4c7fdaee3a32108b0ed508a7593ee 430 PRINTS PR00148 Enolase signature 108 124 2.2E-50 T 31-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TK2106 ebe4c7fdaee3a32108b0ed508a7593ee 430 PRINTS PR00148 Enolase signature 366 383 2.2E-50 T 31-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TK2106 ebe4c7fdaee3a32108b0ed508a7593ee 430 PRINTS PR00148 Enolase signature 337 351 2.2E-50 T 31-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TK2106 ebe4c7fdaee3a32108b0ed508a7593ee 430 PRINTS PR00148 Enolase signature 39 53 2.2E-50 T 31-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TK2106 ebe4c7fdaee3a32108b0ed508a7593ee 430 PRINTS PR00148 Enolase signature 314 325 2.2E-50 T 31-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TK2106 ebe4c7fdaee3a32108b0ed508a7593ee 430 SUPERFAMILY SSF54826 6 140 2.21E-58 T 31-10-2018 TK2106 ebe4c7fdaee3a32108b0ed508a7593ee 430 PIRSF PIRSF001400 3 427 2.8E-196 T 31-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TK2106 ebe4c7fdaee3a32108b0ed508a7593ee 430 SUPERFAMILY SSF51604 139 428 2.23E-125 T 31-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily TK2106 ebe4c7fdaee3a32108b0ed508a7593ee 430 ProSitePatterns PS00164 Enolase signature. 337 350 - T 31-10-2018 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TK2106 ebe4c7fdaee3a32108b0ed508a7593ee 430 Gene3D G3DSA:3.30.390.10 2 128 6.0E-57 T 31-10-2018 IPR029017 Enolase-like, N-terminal TK2106 ebe4c7fdaee3a32108b0ed508a7593ee 430 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 7 426 1.6E-199 T 31-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TK2106 ebe4c7fdaee3a32108b0ed508a7593ee 430 Gene3D G3DSA:3.20.20.120 129 428 1.2E-133 T 31-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily TK2106 ebe4c7fdaee3a32108b0ed508a7593ee 430 SMART SM01193 7 135 4.2E-96 T 31-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TK2106 ebe4c7fdaee3a32108b0ed508a7593ee 430 SMART SM01192 140 428 8.9E-205 T 31-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TK2106 ebe4c7fdaee3a32108b0ed508a7593ee 430 Hamap MF_00318 Enolase [eno]. 5 414 45.994 T 31-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TK0134 7d6b4205b3c75cbd81bad95bb8a4df06 334 Gene3D G3DSA:3.40.800.20 6 317 2.4E-82 T 31-10-2018 IPR037138 Histone deacetylase domain superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 TK0134 7d6b4205b3c75cbd81bad95bb8a4df06 334 Pfam PF00850 Histone deacetylase domain 20 288 1.1E-69 T 31-10-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 TK0134 7d6b4205b3c75cbd81bad95bb8a4df06 334 SUPERFAMILY SSF52768 2 333 3.69E-88 T 31-10-2018 IPR023696 Ureohydrolase domain superfamily TK0134 7d6b4205b3c75cbd81bad95bb8a4df06 334 PRINTS PR01270 Histone deacetylase superfamily signature 123 146 2.2E-10 T 31-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 TK0134 7d6b4205b3c75cbd81bad95bb8a4df06 334 PRINTS PR01270 Histone deacetylase superfamily signature 155 170 2.2E-10 T 31-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 TK0134 7d6b4205b3c75cbd81bad95bb8a4df06 334 PRINTS PR01270 Histone deacetylase superfamily signature 239 249 2.2E-10 T 31-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 TK1914 ecb35f77fc9da65d10232d3cd5a69735 216 Gene3D G3DSA:3.60.21.10 20 132 3.5E-9 T 31-10-2018 IPR029052 Metallo-dependent phosphatase-like TK1914 ecb35f77fc9da65d10232d3cd5a69735 216 PIRSF PIRSF000887 5 214 3.0E-39 T 31-10-2018 IPR024173 Phosphoesterase, MJ0037 TK1914 ecb35f77fc9da65d10232d3cd5a69735 216 SUPERFAMILY SSF56300 20 156 3.8E-15 T 31-10-2018 TK1914 ecb35f77fc9da65d10232d3cd5a69735 216 Pfam PF00149 Calcineurin-like phosphoesterase 20 113 1.0E-9 T 31-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 TK1121 59cae8249b25caca4b3ec152cee4d951 142 SUPERFAMILY SSF46579 9 138 1.05E-25 T 31-10-2018 TK1121 59cae8249b25caca4b3ec152cee4d951 142 Hamap MF_00308 Prefoldin subunit alpha [pfdA]. 4 139 15.201 T 31-10-2018 IPR011599 Prefoldin alpha subunit, archaea-type GO:0006457|GO:0016272|GO:0051082 Reactome: R-HSA-389957 TK1121 59cae8249b25caca4b3ec152cee4d951 142 Pfam PF02996 Prefoldin subunit 22 137 2.6E-22 T 31-10-2018 IPR004127 Prefoldin alpha-like TK1121 59cae8249b25caca4b3ec152cee4d951 142 Gene3D G3DSA:1.10.287.370 8 140 2.3E-34 T 31-10-2018 IPR009053 Prefoldin TK1121 59cae8249b25caca4b3ec152cee4d951 142 TIGRFAM TIGR00293 TIGR00293: prefoldin, alpha subunit 10 138 1.2E-25 T 31-10-2018 IPR011599 Prefoldin alpha subunit, archaea-type GO:0006457|GO:0016272|GO:0051082 Reactome: R-HSA-389957 TK0908 c8e71db2d5bd6d7d57d517376dabb52a 440 ProSitePatterns PS00144 Asparaginase / glutaminase active site signature 1. 98 106 - T 31-10-2018 IPR020827 Asparaginase/glutaminase, active site 1 GO:0006520 TK0908 c8e71db2d5bd6d7d57d517376dabb52a 440 Pfam PF00710 Asparaginase, N-terminal 96 289 5.4E-62 T 31-10-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 TK0908 c8e71db2d5bd6d7d57d517376dabb52a 440 TIGRFAM TIGR02153 gatD_arch: glutamyl-tRNA(Gln) amidotransferase, subunit D 32 434 2.3E-195 T 31-10-2018 IPR011878 Glutamyl-tRNA(Gln) amidotransferase subunit D GO:0006450 TK0908 c8e71db2d5bd6d7d57d517376dabb52a 440 ProSitePatterns PS00917 Asparaginase / glutaminase active site signature 2. 173 183 - T 31-10-2018 IPR027475 Asparaginase/glutaminase, active site 2 Reactome: R-HSA-70614 TK0908 c8e71db2d5bd6d7d57d517376dabb52a 440 PIRSF PIRSF001220 90 429 7.5E-113 T 31-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 TK0908 c8e71db2d5bd6d7d57d517376dabb52a 440 PRINTS PR00139 Asparaginase/glutaminase family signature 172 190 3.9E-19 T 31-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 TK0908 c8e71db2d5bd6d7d57d517376dabb52a 440 PRINTS PR00139 Asparaginase/glutaminase family signature 355 373 3.9E-19 T 31-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 TK0908 c8e71db2d5bd6d7d57d517376dabb52a 440 PRINTS PR00139 Asparaginase/glutaminase family signature 96 107 3.9E-19 T 31-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 TK0908 c8e71db2d5bd6d7d57d517376dabb52a 440 SMART SM00870 95 418 2.9E-157 T 31-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 TK0908 c8e71db2d5bd6d7d57d517376dabb52a 440 Hamap MF_00586 Glutamyl-tRNA(Gln) amidotransferase subunit D [gatD]. 20 434 48.755 T 31-10-2018 IPR011878 Glutamyl-tRNA(Gln) amidotransferase subunit D GO:0006450 TK0908 c8e71db2d5bd6d7d57d517376dabb52a 440 PIRSF PIRSF500175 14 438 1.5E-187 T 31-10-2018 IPR011878 Glutamyl-tRNA(Gln) amidotransferase subunit D GO:0006450 TK0908 c8e71db2d5bd6d7d57d517376dabb52a 440 Gene3D G3DSA:3.40.50.1170 82 302 2.6E-86 T 31-10-2018 IPR037152 L-asparaginase, N-terminal domain superfamily Reactome: R-HSA-70614 TK0908 c8e71db2d5bd6d7d57d517376dabb52a 440 Gene3D G3DSA:2.30.30.520 3 80 6.1E-22 T 31-10-2018 IPR037222 GatD, N-terminal TK0908 c8e71db2d5bd6d7d57d517376dabb52a 440 SUPERFAMILY SSF53774 90 437 1.31E-119 T 31-10-2018 IPR036152 Asparaginase/glutaminase-like superfamily Reactome: R-HSA-70614 TK0908 c8e71db2d5bd6d7d57d517376dabb52a 440 TIGRFAM TIGR00519 asnASE_I: L-asparaginase, type I 93 430 5.5E-146 T 31-10-2018 IPR006033 L-asparaginase, type I GO:0004067|GO:0006520 Reactome: R-HSA-70614 TK0908 c8e71db2d5bd6d7d57d517376dabb52a 440 Gene3D G3DSA:3.40.50.40 303 440 3.0E-57 T 31-10-2018 IPR027473 L-asparaginase, C-terminal Reactome: R-HSA-70614 TK0908 c8e71db2d5bd6d7d57d517376dabb52a 440 SUPERFAMILY SSF141300 5 76 1.7E-20 T 31-10-2018 IPR037222 GatD, N-terminal TK1569 44ea20e10ddeac163625a22141c53c6e 354 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 142 170 - T 31-10-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 TK1569 44ea20e10ddeac163625a22141c53c6e 354 Pfam PF00465 Iron-containing alcohol dehydrogenase 1 345 2.7E-106 T 31-10-2018 IPR001670 Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 TK1569 44ea20e10ddeac163625a22141c53c6e 354 SUPERFAMILY SSF56796 1 354 9.03E-109 T 31-10-2018 TK1569 44ea20e10ddeac163625a22141c53c6e 354 Gene3D G3DSA:3.40.50.1970 1 153 6.5E-49 T 31-10-2018 TK1569 44ea20e10ddeac163625a22141c53c6e 354 Gene3D G3DSA:1.20.1090.10 154 353 5.1E-53 T 31-10-2018 TK1775 33569bd7229b8cfae9cfb7f15322d675 372 Gene3D G3DSA:2.40.50.100 245 304 7.0E-25 T 31-10-2018 TK1775 33569bd7229b8cfae9cfb7f15322d675 372 Pfam PF08402 TOBE domain 288 363 1.1E-5 T 31-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 TK1775 33569bd7229b8cfae9cfb7f15322d675 372 SUPERFAMILY SSF52540 4 249 3.5E-90 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK1775 33569bd7229b8cfae9cfb7f15322d675 372 SMART SM00382 28 217 1.7E-13 T 31-10-2018 IPR003593 AAA+ ATPase domain TK1775 33569bd7229b8cfae9cfb7f15322d675 372 Gene3D G3DSA:2.40.50.140 310 354 7.7E-23 T 31-10-2018 TK1775 33569bd7229b8cfae9cfb7f15322d675 372 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TK1775 33569bd7229b8cfae9cfb7f15322d675 372 Gene3D G3DSA:3.40.50.300 1 243 5.6E-78 T 31-10-2018 TK1775 33569bd7229b8cfae9cfb7f15322d675 372 SUPERFAMILY SSF50331 242 370 7.78E-25 T 31-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal TK1775 33569bd7229b8cfae9cfb7f15322d675 372 Pfam PF00005 ABC transporter 20 167 4.1E-32 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TK1736 c82d7f37c04209acb69493c290785a9e 1746 SUPERFAMILY SSF51998 755 1618 5.13E-136 T 31-10-2018 TK1736 c82d7f37c04209acb69493c290785a9e 1746 Pfam PF14890 Intein splicing domain 995 1296 2.3E-21 T 31-10-2018 TK1736 c82d7f37c04209acb69493c290785a9e 1746 Gene3D G3DSA:2.170.16.10 322 752 1.3E-181 T 31-10-2018 TK1736 c82d7f37c04209acb69493c290785a9e 1746 Pfam PF02867 Ribonucleotide reductase, barrel domain 756 1607 6.0E-224 T 31-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TK1736 c82d7f37c04209acb69493c290785a9e 1746 Gene3D G3DSA:3.10.28.10 526 639 1.3E-181 T 31-10-2018 IPR027434 Homing endonuclease TK1736 c82d7f37c04209acb69493c290785a9e 1746 Pfam PF03477 ATP cone domain 5 93 6.3E-21 T 31-10-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 TK1736 c82d7f37c04209acb69493c290785a9e 1746 SMART SM00306 300 429 1.6E-20 T 31-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TK1736 c82d7f37c04209acb69493c290785a9e 1746 SMART SM00306 913 1044 4.0E-27 T 31-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TK1736 c82d7f37c04209acb69493c290785a9e 1746 SMART SM00305 1257 1302 7.2E-11 T 31-10-2018 IPR003586 Hint domain C-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TK1736 c82d7f37c04209acb69493c290785a9e 1746 SMART SM00305 715 761 1.9E-7 T 31-10-2018 IPR003586 Hint domain C-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TK1736 c82d7f37c04209acb69493c290785a9e 1746 Gene3D G3DSA:3.10.28.10 439 525 1.3E-181 T 31-10-2018 IPR027434 Homing endonuclease TK1736 c82d7f37c04209acb69493c290785a9e 1746 Pfam PF14890 Intein splicing domain 309 755 1.7E-48 T 31-10-2018 TK1736 c82d7f37c04209acb69493c290785a9e 1746 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 732 756 1.2E-6 T 31-10-2018 IPR030934 Intein C-terminal splicing region TK1736 c82d7f37c04209acb69493c290785a9e 1746 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 1276 1297 5.2E-8 T 31-10-2018 IPR030934 Intein C-terminal splicing region TK1736 c82d7f37c04209acb69493c290785a9e 1746 Pfam PF14528 LAGLIDADG-like domain 542 615 1.2E-12 T 31-10-2018 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 TK1736 c82d7f37c04209acb69493c290785a9e 1746 Pfam PF14528 LAGLIDADG-like domain 1153 1242 1.3E-20 T 31-10-2018 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 TK1736 c82d7f37c04209acb69493c290785a9e 1746 Gene3D G3DSA:3.20.70.20 169 303 1.7E-19 T 31-10-2018 TK1736 c82d7f37c04209acb69493c290785a9e 1746 Gene3D G3DSA:3.20.70.20 63 166 7.1E-6 T 31-10-2018 TK1736 c82d7f37c04209acb69493c290785a9e 1746 SUPERFAMILY SSF55608 430 527 7.42E-48 T 31-10-2018 IPR027434 Homing endonuclease TK1736 c82d7f37c04209acb69493c290785a9e 1746 Gene3D G3DSA:3.20.70.20 1275 1622 1.5E-118 T 31-10-2018 TK1736 c82d7f37c04209acb69493c290785a9e 1746 Gene3D G3DSA:3.20.70.20 753 915 1.2E-54 T 31-10-2018 TK1736 c82d7f37c04209acb69493c290785a9e 1746 SUPERFAMILY SSF54786 637 715 3.77E-42 T 31-10-2018 TK1736 c82d7f37c04209acb69493c290785a9e 1746 Gene3D G3DSA:3.10.28.10 1057 1215 8.2E-33 T 31-10-2018 IPR027434 Homing endonuclease TK1736 c82d7f37c04209acb69493c290785a9e 1746 PRINTS PR00379 Intein signature 1291 1300 3.9E-27 T 31-10-2018 IPR006142 Intein GO:0016539 TK1736 c82d7f37c04209acb69493c290785a9e 1746 PRINTS PR00379 Intein signature 1011 1024 3.9E-27 T 31-10-2018 IPR006142 Intein GO:0016539 TK1736 c82d7f37c04209acb69493c290785a9e 1746 PRINTS PR00379 Intein signature 1154 1166 3.9E-27 T 31-10-2018 IPR006142 Intein GO:0016539 TK1736 c82d7f37c04209acb69493c290785a9e 1746 PRINTS PR00379 Intein signature 1181 1196 3.9E-27 T 31-10-2018 IPR006142 Intein GO:0016539 TK1736 c82d7f37c04209acb69493c290785a9e 1746 PRINTS PR00379 Intein signature 1060 1072 3.9E-27 T 31-10-2018 IPR006142 Intein GO:0016539 TK1736 c82d7f37c04209acb69493c290785a9e 1746 PRINTS PR00379 Intein signature 1273 1290 3.9E-27 T 31-10-2018 IPR006142 Intein GO:0016539 TK1736 c82d7f37c04209acb69493c290785a9e 1746 Gene3D G3DSA:2.170.16.10 916 1056 2.3E-14 T 31-10-2018 TK1736 c82d7f37c04209acb69493c290785a9e 1746 TIGRFAM TIGR01445 intein_Nterm: intein N-terminal splicing region 915 1024 2.2E-19 T 31-10-2018 IPR006141 Intein N-terminal splicing region GO:0016539 Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TK1736 c82d7f37c04209acb69493c290785a9e 1746 TIGRFAM TIGR01445 intein_Nterm: intein N-terminal splicing region 302 404 2.2E-12 T 31-10-2018 IPR006141 Intein N-terminal splicing region GO:0016539 Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TK1736 c82d7f37c04209acb69493c290785a9e 1746 SUPERFAMILY SSF55608 1136 1249 9.14E-20 T 31-10-2018 IPR027434 Homing endonuclease TK1736 c82d7f37c04209acb69493c290785a9e 1746 TIGRFAM TIGR02504 NrdJ_Z: ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent 1296 1616 7.3E-128 T 31-10-2018 IPR013344 Ribonucleotide reductase, adenosylcobalamin-dependent GO:0000166|GO:0004748|GO:0031419|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TK1736 c82d7f37c04209acb69493c290785a9e 1746 Gene3D G3DSA:3.30.160.90 640 715 1.3E-181 T 31-10-2018 TK1736 c82d7f37c04209acb69493c290785a9e 1746 SUPERFAMILY SSF48168 9 155 1.46E-12 T 31-10-2018 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TK1736 c82d7f37c04209acb69493c290785a9e 1746 SUPERFAMILY SSF51294 302 756 1.43E-43 T 31-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TK1736 c82d7f37c04209acb69493c290785a9e 1746 SUPERFAMILY SSF51294 914 1296 2.55E-41 T 31-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TK1736 c82d7f37c04209acb69493c290785a9e 1746 SUPERFAMILY SSF51998 213 302 1.77E-6 T 31-10-2018 TK1736 c82d7f37c04209acb69493c290785a9e 1746 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 113 268 2.3E-28 T 31-10-2018 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TK1736 c82d7f37c04209acb69493c290785a9e 1746 SUPERFAMILY SSF55608 528 630 6.5E-22 T 31-10-2018 IPR027434 Homing endonuclease TK1736 c82d7f37c04209acb69493c290785a9e 1746 Pfam PF09062 PI-PfuI Endonuclease subdomain 430 527 8.0E-59 T 31-10-2018 IPR015147 PI-PfuI intein endonuclease, subdomain KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TK1736 c82d7f37c04209acb69493c290785a9e 1746 Pfam PF09061 Stirrup 637 715 7.7E-51 T 31-10-2018 IPR015146 Ribonucleotide reductase, stirrup GO:0016788 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TK1511 688228f4daeb6b6a58067bd0fbcaf17b 73 Gene3D G3DSA:3.30.160.250 3 66 1.3E-10 T 31-10-2018 TK1511 688228f4daeb6b6a58067bd0fbcaf17b 73 SUPERFAMILY SSF143100 6 56 3.4E-12 T 31-10-2018 IPR035069 TTHA1013/TTHA0281-like TK1310 4d96ce53e82f7d8ad4b0d767234bcaf9 70 Hamap MF_00292 30S ribosomal protein S28e [rps28e]. 1 67 25.514 T 31-10-2018 IPR000289 Ribosomal protein S28e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1310 4d96ce53e82f7d8ad4b0d767234bcaf9 70 Pfam PF01200 Ribosomal protein S28e 4 66 1.9E-30 T 31-10-2018 IPR000289 Ribosomal protein S28e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1310 4d96ce53e82f7d8ad4b0d767234bcaf9 70 Gene3D G3DSA:2.40.50.140 1 70 7.3E-33 T 31-10-2018 TK1310 4d96ce53e82f7d8ad4b0d767234bcaf9 70 ProDom PD005541 RIBOSOMAL RIBONUCLEOPROTEIN 40S S28 S28E 30S ACETYLATION S33 S33 CG15527 1 48 6.0E-11 T 31-10-2018 IPR000289 Ribosomal protein S28e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1310 4d96ce53e82f7d8ad4b0d767234bcaf9 70 ProSitePatterns PS00961 Ribosomal protein S28e signature. 58 66 - T 31-10-2018 IPR028626 Ribosomal protein S28e conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1310 4d96ce53e82f7d8ad4b0d767234bcaf9 70 SUPERFAMILY SSF50249 3 69 4.17E-26 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold TK1782 131feac0e2b9eeebaba5fa6ba84f1bd4 426 SUPERFAMILY SSF56574 53 423 3.93E-125 T 31-10-2018 IPR036186 Serpin superfamily TK1782 131feac0e2b9eeebaba5fa6ba84f1bd4 426 ProSitePatterns PS00284 Serpins signature. 396 406 - T 31-10-2018 IPR023795 Serpin, conserved site TK1782 131feac0e2b9eeebaba5fa6ba84f1bd4 426 Gene3D G3DSA:3.30.497.10 66 368 6.4E-128 T 31-10-2018 TK1782 131feac0e2b9eeebaba5fa6ba84f1bd4 426 Pfam PF00079 Serpin (serine protease inhibitor) 62 423 1.2E-119 T 31-10-2018 IPR023796 Serpin domain TK1782 131feac0e2b9eeebaba5fa6ba84f1bd4 426 Gene3D G3DSA:2.30.39.10 225 423 6.4E-128 T 31-10-2018 TK1782 131feac0e2b9eeebaba5fa6ba84f1bd4 426 SMART SM00093 68 423 2.8E-137 T 31-10-2018 IPR023796 Serpin domain TK0170 ba4eb5d9d8d6d5070476d143193c3f54 281 SMART SM00518 4 276 9.1E-97 T 31-10-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 TK0170 ba4eb5d9d8d6d5070476d143193c3f54 281 Pfam PF01261 Xylose isomerase-like TIM barrel 28 239 1.4E-20 T 31-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain TK0170 ba4eb5d9d8d6d5070476d143193c3f54 281 Gene3D G3DSA:3.20.20.150 13 281 2.9E-43 T 31-10-2018 TK0170 ba4eb5d9d8d6d5070476d143193c3f54 281 SUPERFAMILY SSF51658 7 279 3.22E-64 T 31-10-2018 IPR036237 Xylose isomerase-like superfamily TK1805 8555dbaf308e65f7318836f9d68845f1 409 Hamap MF_00220_A Dihydroorotase [pyrC]. 4 395 65.88 T 31-10-2018 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TK1805 8555dbaf308e65f7318836f9d68845f1 409 SUPERFAMILY SSF51556 52 334 7.71E-73 T 31-10-2018 IPR032466 Metal-dependent hydrolase TK1805 8555dbaf308e65f7318836f9d68845f1 409 Pfam PF01979 Amidohydrolase family 48 101 5.5E-11 T 31-10-2018 IPR006680 Amidohydrolase-related GO:0016787 TK1805 8555dbaf308e65f7318836f9d68845f1 409 SUPERFAMILY SSF51338 4 397 8.1E-20 T 31-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 TK1805 8555dbaf308e65f7318836f9d68845f1 409 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 15 389 1.3E-116 T 31-10-2018 TK1805 8555dbaf308e65f7318836f9d68845f1 409 ProSitePatterns PS00483 Dihydroorotase signature 2. 274 285 - T 31-10-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TK1805 8555dbaf308e65f7318836f9d68845f1 409 Gene3D G3DSA:3.20.20.140 42 405 5.5E-104 T 31-10-2018 TK2142 beb9e25720a50fd574f8d479ce05db2e 552 Pfam PF03553 Na+/H+ antiporter family 156 507 8.4E-66 T 31-10-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 TK0757 8c4fff02b755f08aac288d02f9ced9da 380 Pfam PF13343 Bacterial extracellular solute-binding protein 78 300 2.4E-25 T 31-10-2018 TK0757 8c4fff02b755f08aac288d02f9ced9da 380 SUPERFAMILY SSF53850 26 334 4.09E-74 T 31-10-2018 TK0757 8c4fff02b755f08aac288d02f9ced9da 380 PIRSF PIRSF002825 8 338 5.2E-51 T 31-10-2018 IPR026045 Ferric binding protein TK0757 8c4fff02b755f08aac288d02f9ced9da 380 Gene3D G3DSA:3.40.190.10 31 307 1.2E-104 T 31-10-2018 TK0757 8c4fff02b755f08aac288d02f9ced9da 380 Gene3D G3DSA:3.40.190.10 132 334 1.2E-104 T 31-10-2018 TK0757 8c4fff02b755f08aac288d02f9ced9da 380 TIGRFAM TIGR04288 CGP_CTERM: CGP-CTERM domain 360 379 7.0E-7 T 31-10-2018 IPR027552 CGP-CTERM domain TK0757 8c4fff02b755f08aac288d02f9ced9da 380 TIGRFAM TIGR01254 sfuA: ABC transporter periplasmic binding protein, thiB subfamily 26 333 1.3E-80 T 31-10-2018 IPR005948 Thiamine/thiamin pyrophosphate-binding periplasmic protein, ABC transporter GO:0015888|GO:0030975 TK0522 4c286beb8af4825872a3e354a3c2cd17 449 SUPERFAMILY SSF49452 88 186 9.53E-15 T 31-10-2018 IPR013784 Carbohydrate-binding-like fold GO:0030246 TK0522 4c286beb8af4825872a3e354a3c2cd17 449 Gene3D G3DSA:3.40.50.1820 197 449 8.9E-66 T 31-10-2018 IPR029058 Alpha/Beta hydrolase fold TK0522 4c286beb8af4825872a3e354a3c2cd17 449 SMART SM01065 88 183 7.4E-14 T 31-10-2018 IPR002044 Carbohydrate binding module family 20 GO:2001070 TK0522 4c286beb8af4825872a3e354a3c2cd17 449 SUPERFAMILY SSF53474 199 448 1.2E-55 T 31-10-2018 IPR029058 Alpha/Beta hydrolase fold TK0522 4c286beb8af4825872a3e354a3c2cd17 449 Gene3D G3DSA:2.60.40.10 78 184 2.0E-10 T 31-10-2018 IPR013783 Immunoglobulin-like fold TK0522 4c286beb8af4825872a3e354a3c2cd17 449 Pfam PF00756 Putative esterase 213 445 8.5E-33 T 31-10-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 TK1041 75d77c2070878861efe2a340773c6cdc 136 SMART SM00418 55 133 1.7E-11 T 31-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TK1041 75d77c2070878861efe2a340773c6cdc 136 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 89 104 3.2E-8 T 31-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TK1041 75d77c2070878861efe2a340773c6cdc 136 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 57 72 3.2E-8 T 31-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TK1041 75d77c2070878861efe2a340773c6cdc 136 SUPERFAMILY SSF46785 50 121 1.36E-18 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TK1041 75d77c2070878861efe2a340773c6cdc 136 Gene3D G3DSA:1.10.10.10 42 133 1.9E-19 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TK1041 75d77c2070878861efe2a340773c6cdc 136 Pfam PF01022 Bacterial regulatory protein, arsR family 62 108 9.4E-14 T 31-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TK2135 0b5a00de943bdbc4a4d05f1d4249134f 417 Gene3D G3DSA:2.40.50.140 2 62 9.3E-16 T 31-10-2018 TK2135 0b5a00de943bdbc4a4d05f1d4249134f 417 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 247 325 1.6E-6 T 31-10-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 TK2135 0b5a00de943bdbc4a4d05f1d4249134f 417 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 335 416 7.2E-18 T 31-10-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 TK2135 0b5a00de943bdbc4a4d05f1d4249134f 417 Gene3D G3DSA:3.40.50.150 74 411 2.2E-121 T 31-10-2018 TK2135 0b5a00de943bdbc4a4d05f1d4249134f 417 SUPERFAMILY SSF50249 2 59 4.63E-8 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold TK2135 0b5a00de943bdbc4a4d05f1d4249134f 417 SUPERFAMILY SSF53335 61 416 2.91E-73 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TK2135 0b5a00de943bdbc4a4d05f1d4249134f 417 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 348 379 - T 31-10-2018 IPR030390 RNA methyltransferase TrmA, active site TK2135 0b5a00de943bdbc4a4d05f1d4249134f 417 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 9 409 1.2E-86 T 31-10-2018 TK2135 0b5a00de943bdbc4a4d05f1d4249134f 417 Gene3D G3DSA:3.40.1350.30 113 258 2.2E-121 T 31-10-2018 TK2135 0b5a00de943bdbc4a4d05f1d4249134f 417 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 399 409 - T 31-10-2018 IPR030391 RNA methyltransferase TrmA, conserved site TK1798 f0bdeb88e41a50738fa22ffe01e11924 254 TIGRFAM TIGR00552 nadE: NAD+ synthetase 8 249 8.1E-81 T 31-10-2018 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 TK1798 f0bdeb88e41a50738fa22ffe01e11924 254 SUPERFAMILY SSF52402 3 250 3.09E-77 T 31-10-2018 TK1798 f0bdeb88e41a50738fa22ffe01e11924 254 Hamap MF_00193 NH(3)-dependent NAD(+) synthetase [nadE]. 5 252 51.532 T 31-10-2018 IPR022926 NH(3)-dependent NAD(+) synthetase GO:0008795|GO:0009435 KEGG: 00760+6.3.1.5 TK1798 f0bdeb88e41a50738fa22ffe01e11924 254 Gene3D G3DSA:3.40.50.620 6 254 6.4E-93 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TK1798 f0bdeb88e41a50738fa22ffe01e11924 254 Pfam PF02540 NAD synthase 10 249 6.2E-85 T 31-10-2018 IPR022310 NAD/GMP synthase TK1532 4da015dd02c3a4edc5c11375263b0b35 114 SUPERFAMILY SSF50249 29 108 4.71E-28 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold TK1532 4da015dd02c3a4edc5c11375263b0b35 114 Pfam PF00366 Ribosomal protein S17 35 102 4.7E-27 T 31-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TK1532 4da015dd02c3a4edc5c11375263b0b35 114 TIGRFAM TIGR03630 uS17_arch: ribosomal protein uS17 4 104 3.0E-47 T 31-10-2018 IPR028333 Ribosomal protein S17, archaeal/eukaryotic Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1532 4da015dd02c3a4edc5c11375263b0b35 114 PRINTS PR00973 Ribosomal protein S17 family signature 82 92 2.8E-11 T 31-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TK1532 4da015dd02c3a4edc5c11375263b0b35 114 PRINTS PR00973 Ribosomal protein S17 family signature 92 99 2.8E-11 T 31-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TK1532 4da015dd02c3a4edc5c11375263b0b35 114 PRINTS PR00973 Ribosomal protein S17 family signature 49 72 2.8E-11 T 31-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TK1532 4da015dd02c3a4edc5c11375263b0b35 114 ProSitePatterns PS00056 Ribosomal protein S17 signature. 82 94 - T 31-10-2018 IPR019979 Ribosomal protein S17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1532 4da015dd02c3a4edc5c11375263b0b35 114 Hamap MF_01345_A 30S ribosomal protein S17 [rpsQ]. 2 106 33.033 T 31-10-2018 IPR019978 Ribosomal protein S17, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 TK1532 4da015dd02c3a4edc5c11375263b0b35 114 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 31 102 7.0E-35 T 31-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TK1532 4da015dd02c3a4edc5c11375263b0b35 114 Gene3D G3DSA:2.40.50.1000 1 113 2.4E-39 T 31-10-2018 TK2205 5fbe307ac8f5e897c083512476922557 381 Gene3D G3DSA:3.40.50.1100 91 186 4.9E-111 T 31-10-2018 TK2205 5fbe307ac8f5e897c083512476922557 381 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 57 353 2.3E-73 T 31-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme TK2205 5fbe307ac8f5e897c083512476922557 381 TIGRFAM TIGR00260 thrC: threonine synthase 51 357 2.5E-63 T 31-10-2018 IPR004450 Threonine synthase-like TK2205 5fbe307ac8f5e897c083512476922557 381 PIRSF PIRSF038945 28 372 2.1E-83 T 31-10-2018 IPR026260 Threonine synthase, bacterial/archaeal GO:0004795|GO:0009088 KEGG: 00260+4.2.3.1|KEGG: 00750+4.2.3.1 TK2205 5fbe307ac8f5e897c083512476922557 381 Gene3D G3DSA:3.40.50.1100 43 357 4.9E-111 T 31-10-2018 TK2205 5fbe307ac8f5e897c083512476922557 381 SUPERFAMILY SSF53686 3 359 6.55E-90 T 31-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme TK0658 9047968048c7d4ecfbe1acc196bc90cf 508 Gene3D G3DSA:3.40.50.300 1 243 1.0E-58 T 31-10-2018 TK0658 9047968048c7d4ecfbe1acc196bc90cf 508 Pfam PF00005 ABC transporter 24 174 4.1E-28 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TK0658 9047968048c7d4ecfbe1acc196bc90cf 508 SMART SM00382 33 222 3.0E-14 T 31-10-2018 IPR003593 AAA+ ATPase domain TK0658 9047968048c7d4ecfbe1acc196bc90cf 508 SUPERFAMILY SSF52540 243 496 2.11E-47 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK0658 9047968048c7d4ecfbe1acc196bc90cf 508 Gene3D G3DSA:3.40.50.300 257 502 6.4E-44 T 31-10-2018 TK0658 9047968048c7d4ecfbe1acc196bc90cf 508 SUPERFAMILY SSF52540 6 232 7.56E-60 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK0658 9047968048c7d4ecfbe1acc196bc90cf 508 Pfam PF00005 ABC transporter 279 435 6.9E-16 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TK0658 9047968048c7d4ecfbe1acc196bc90cf 508 ProSitePatterns PS00211 ABC transporters family signature. 408 422 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TK0830 7318ff1e0f789b857c99dffc39ec89dd 67 Gene3D G3DSA:3.40.50.300 5 63 3.1E-11 T 31-10-2018 TK0830 7318ff1e0f789b857c99dffc39ec89dd 67 SUPERFAMILY SSF52540 4 55 8.33E-9 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK0830 7318ff1e0f789b857c99dffc39ec89dd 67 Pfam PF06745 KaiC 9 59 1.1E-15 T 31-10-2018 IPR014774 KaiC-like domain TK2046 ba4976c5285fa100f3be26fbfd6c4c20 466 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 305 383 2.9E-7 T 31-10-2018 IPR007404 LexA-binding, inner membrane-associated putative hydrolase TK0175 2b600ad9824f2d5ef478c4f5b4465a39 198 Pfam PF02676 Methyltransferase TYW3 11 193 1.6E-45 T 31-10-2018 IPR003827 tRNA wybutosine-synthesizing protein MetaCyc: PWY-7286|Reactome: R-HSA-6782861 TK0175 2b600ad9824f2d5ef478c4f5b4465a39 198 Gene3D G3DSA:3.30.1960.10 2 197 3.3E-68 T 31-10-2018 IPR036602 tRNA wybutosine-synthesizing-like superfamily MetaCyc: PWY-7286|Reactome: R-HSA-6782861 TK0175 2b600ad9824f2d5ef478c4f5b4465a39 198 SUPERFAMILY SSF111278 7 193 1.09E-61 T 31-10-2018 IPR036602 tRNA wybutosine-synthesizing-like superfamily MetaCyc: PWY-7286|Reactome: R-HSA-6782861 TK0175 2b600ad9824f2d5ef478c4f5b4465a39 198 Hamap MF_00266 tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase [taw3]. 9 195 30.771 T 31-10-2018 IPR022908 tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase GO:0008175|GO:0030488|GO:0031591 MetaCyc: PWY-7286 TK1715 35531ed9aed08287a77b3c296de0e3c1 397 Gene3D G3DSA:3.40.50.11820 26 186 6.2E-53 T 31-10-2018 TK1715 35531ed9aed08287a77b3c296de0e3c1 397 SUPERFAMILY SSF53756 112 392 1.32E-15 T 31-10-2018 TK1715 35531ed9aed08287a77b3c296de0e3c1 397 Gene3D G3DSA:3.40.50.12580 187 372 6.2E-53 T 31-10-2018 TK1715 35531ed9aed08287a77b3c296de0e3c1 397 Pfam PF04464 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase 20 392 4.9E-61 T 31-10-2018 IPR007554 CDP-glycerol glycerophosphotransferase GO:0016020|GO:0047355 TK1454 368c40825294e32349a9952adf4e4316 194 Gene3D G3DSA:3.40.1120.10 1 193 7.6E-90 T 31-10-2018 IPR024794 Ribosomal protein L15e core domain superfamily GO:0003735|GO:0005840 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1454 368c40825294e32349a9952adf4e4316 194 Hamap MF_00256 50S ribosomal protein L15e [rpl15e]. 1 193 43.054 T 31-10-2018 IPR020926 Ribosomal protein L15e, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 TK1454 368c40825294e32349a9952adf4e4316 194 ProSitePatterns PS01194 Ribosomal protein L15e signature. 46 69 - T 31-10-2018 IPR020925 Ribosomal protein L15e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1454 368c40825294e32349a9952adf4e4316 194 SMART SM01384 2 191 7.4E-133 T 31-10-2018 IPR000439 Ribosomal protein L15e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1454 368c40825294e32349a9952adf4e4316 194 SUPERFAMILY SSF54189 1 191 9.11E-87 T 31-10-2018 IPR012678 Ribosomal protein L23/L15e core domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 TK1454 368c40825294e32349a9952adf4e4316 194 Pfam PF00827 Ribosomal L15 2 189 5.1E-89 T 31-10-2018 IPR000439 Ribosomal protein L15e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1252 95babcfffbbdfb0aa9469dedbdb63680 477 Pfam PF02272 DHHA1 domain 328 464 9.0E-23 T 31-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 TK1252 95babcfffbbdfb0aa9469dedbdb63680 477 Gene3D G3DSA:3.90.1640.30 2 220 4.8E-19 T 31-10-2018 TK1252 95babcfffbbdfb0aa9469dedbdb63680 477 SUPERFAMILY SSF64182 7 469 1.57E-64 T 31-10-2018 IPR038763 DHH phosphoesterase superfamily TK1252 95babcfffbbdfb0aa9469dedbdb63680 477 Gene3D G3DSA:3.10.310.30 336 468 8.2E-10 T 31-10-2018 TK2276 6a0152ad4c0d06aa16e536c946474546 213 SMART SM00934 5 205 2.0E-64 T 31-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TK2276 6a0152ad4c0d06aa16e536c946474546 213 Gene3D G3DSA:3.20.20.70 5 210 2.7E-66 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TK2276 6a0152ad4c0d06aa16e536c946474546 213 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 4 204 1.5E-39 T 31-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TK2276 6a0152ad4c0d06aa16e536c946474546 213 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 58 71 - T 31-10-2018 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TK2276 6a0152ad4c0d06aa16e536c946474546 213 SUPERFAMILY SSF51366 2 211 3.46E-62 T 31-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 TK2276 6a0152ad4c0d06aa16e536c946474546 213 TIGRFAM TIGR01740 pyrF: orotidine 5'-phosphate decarboxylase 6 205 1.7E-51 T 31-10-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TK2276 6a0152ad4c0d06aa16e536c946474546 213 Hamap MF_01200_A Orotidine 5'-phosphate decarboxylase [pyrF]. 6 211 38.434 T 31-10-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TK0591 160c42c642c7293785a500d412294e4d 335 Gene3D G3DSA:3.40.630.30 223 315 2.7E-7 T 31-10-2018 TK0591 160c42c642c7293785a500d412294e4d 335 SUPERFAMILY SSF55729 238 290 7.72E-8 T 31-10-2018 IPR016181 Acyl-CoA N-acyltransferase TK0591 160c42c642c7293785a500d412294e4d 335 Pfam PF00583 Acetyltransferase (GNAT) family 244 309 4.6E-5 T 31-10-2018 IPR000182 GNAT domain TK1995 c698124e1858add66bc87797398fb42a 108 Pfam PF01850 PIN domain 26 98 6.7E-7 T 31-10-2018 IPR002716 PIN domain TK1995 c698124e1858add66bc87797398fb42a 108 Gene3D G3DSA:3.40.50.1010 2 108 9.7E-13 T 31-10-2018 TK1995 c698124e1858add66bc87797398fb42a 108 SUPERFAMILY SSF88723 1 101 5.33E-17 T 31-10-2018 IPR029060 PIN-like domain superfamily TK2126 6e524710c078aab77b1f47b745bdc83d 325 Gene3D G3DSA:3.30.420.40 4 299 5.6E-115 T 31-10-2018 TK2126 6e524710c078aab77b1f47b745bdc83d 325 SUPERFAMILY SSF53067 1 293 7.77E-37 T 31-10-2018 TK2126 6e524710c078aab77b1f47b745bdc83d 325 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 4 291 5.1E-102 T 31-10-2018 IPR017861 Kae1/TsaD family TK2126 6e524710c078aab77b1f47b745bdc83d 325 TIGRFAM TIGR03722 arch_KAE1: universal archaeal protein Kae1 4 324 4.9E-154 T 31-10-2018 IPR022449 tRNA N6-adenosine threonylcarbamoyltransferase Kae1, archaea GO:0000408|GO:0002949 TK2126 6e524710c078aab77b1f47b745bdc83d 325 Gene3D G3DSA:3.30.420.40 122 278 5.6E-115 T 31-10-2018 TK2126 6e524710c078aab77b1f47b745bdc83d 325 Pfam PF00814 Glycoprotease family 23 292 2.3E-96 T 31-10-2018 IPR000905 Gcp-like domain TK2126 6e524710c078aab77b1f47b745bdc83d 325 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 124 136 7.2E-42 T 31-10-2018 IPR017861 Kae1/TsaD family TK2126 6e524710c078aab77b1f47b745bdc83d 325 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 93 112 7.2E-42 T 31-10-2018 IPR017861 Kae1/TsaD family TK2126 6e524710c078aab77b1f47b745bdc83d 325 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 146 167 7.2E-42 T 31-10-2018 IPR017861 Kae1/TsaD family TK2126 6e524710c078aab77b1f47b745bdc83d 325 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 4 17 7.2E-42 T 31-10-2018 IPR017861 Kae1/TsaD family TK2126 6e524710c078aab77b1f47b745bdc83d 325 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 72 92 7.2E-42 T 31-10-2018 IPR017861 Kae1/TsaD family TK2126 6e524710c078aab77b1f47b745bdc83d 325 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 248 257 7.2E-42 T 31-10-2018 IPR017861 Kae1/TsaD family TK2126 6e524710c078aab77b1f47b745bdc83d 325 Hamap MF_01446 tRNA N6-adenosine threonylcarbamoyltransferase [kae1]. 1 325 38.358 T 31-10-2018 IPR034680 tRNA N6-adenosine threonylcarbamoyltransferase Kae1/OSGEP GO:0000408|GO:0002949 Reactome: R-HSA-6782315 TK2126 6e524710c078aab77b1f47b745bdc83d 325 ProSitePatterns PS01016 Glycoprotease family signature. 92 112 - T 31-10-2018 IPR017860 Peptidase M22, conserved site Reactome: R-HSA-6782315 TK1606 de22120e0a9f5b2da3293d19f7ddb608 251 SUPERFAMILY SSF58104 9 241 5.1E-38 T 31-10-2018 TK1606 de22120e0a9f5b2da3293d19f7ddb608 251 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 61 206 3.5E-28 T 31-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TK1606 de22120e0a9f5b2da3293d19f7ddb608 251 Gene3D G3DSA:1.10.287.950 2 250 2.0E-36 T 31-10-2018 TK1606 de22120e0a9f5b2da3293d19f7ddb608 251 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 128 157 1.5E-15 T 31-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TK1606 de22120e0a9f5b2da3293d19f7ddb608 251 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 99 126 1.5E-15 T 31-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TK1606 de22120e0a9f5b2da3293d19f7ddb608 251 SMART SM00283 4 244 2.6E-5 T 31-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TK1636 66db0ec29ca34dedc61a74e4c0065ca5 236 Gene3D G3DSA:3.30.1250.10 8 87 3.1E-31 T 31-10-2018 IPR036786 Ribosome maturation protein SBDS, N-terminal domain superfamily TK1636 66db0ec29ca34dedc61a74e4c0065ca5 236 Pfam PF01172 Shwachman-Bodian-Diamond syndrome (SBDS) protein 8 94 8.1E-26 T 31-10-2018 IPR019783 Ribosome maturation protein SBDS, N-terminal TK1636 66db0ec29ca34dedc61a74e4c0065ca5 236 Gene3D G3DSA:3.30.70.240 163 235 2.9E-29 T 31-10-2018 TK1636 66db0ec29ca34dedc61a74e4c0065ca5 236 ProSitePatterns PS01267 Uncharacterized protein family UPF0023 signature. 37 56 - T 31-10-2018 IPR018023 Ribosome maturation protein SBDS, conserved site TK1636 66db0ec29ca34dedc61a74e4c0065ca5 236 SUPERFAMILY SSF89895 4 87 4.97E-26 T 31-10-2018 IPR036786 Ribosome maturation protein SBDS, N-terminal domain superfamily TK1636 66db0ec29ca34dedc61a74e4c0065ca5 236 Gene3D G3DSA:1.10.10.900 88 162 2.8E-30 T 31-10-2018 IPR037188 Ribosome maturation protein Sdo1/SBDS, central domain superfamily TK1636 66db0ec29ca34dedc61a74e4c0065ca5 236 Pfam PF09377 SBDS protein C-terminal domain 101 216 4.7E-16 T 31-10-2018 IPR018978 Ribosome maturation protein SBDS, C-terminal GO:0042254 TK1636 66db0ec29ca34dedc61a74e4c0065ca5 236 SUPERFAMILY SSF109728 82 155 6.02E-25 T 31-10-2018 IPR037188 Ribosome maturation protein Sdo1/SBDS, central domain superfamily TK1636 66db0ec29ca34dedc61a74e4c0065ca5 236 SUPERFAMILY SSF54980 157 228 1.08E-22 T 31-10-2018 IPR035647 EF-G domain III/V-like TK1636 66db0ec29ca34dedc61a74e4c0065ca5 236 TIGRFAM TIGR00291 RNA_SBDS: rRNA metabolism protein, SBDS family 3 231 2.3E-92 T 31-10-2018 IPR002140 Ribosome maturation protein Sdo1/SBDS GO:0042256 TK1422 c34b89ac64a52e5d326c0940efe8e2e0 272 SUPERFAMILY SSF142535 1 270 2.09E-89 T 31-10-2018 TK1422 c34b89ac64a52e5d326c0940efe8e2e0 272 Gene3D G3DSA:3.40.630.50 1 186 9.6E-70 T 31-10-2018 TK1422 c34b89ac64a52e5d326c0940efe8e2e0 272 PIRSF PIRSF016210 1 272 1.2E-84 T 31-10-2018 IPR018033 D-aminoacyl-tRNA deacylase, archaea GO:0016788|GO:0019478|GO:0051499 TK1422 c34b89ac64a52e5d326c0940efe8e2e0 272 Gene3D G3DSA:3.40.50.10700 187 272 2.5E-32 T 31-10-2018 TK1422 c34b89ac64a52e5d326c0940efe8e2e0 272 Hamap MF_00562 D-aminoacyl-tRNA deacylase [dtdA]. 1 271 36.086 T 31-10-2018 IPR018033 D-aminoacyl-tRNA deacylase, archaea GO:0016788|GO:0019478|GO:0051499 TK1422 c34b89ac64a52e5d326c0940efe8e2e0 272 Pfam PF04414 D-aminoacyl-tRNA deacylase 69 269 1.8E-68 T 31-10-2018 IPR007508 D-aminoacyl-tRNA deacylase DtdA GO:0016788|GO:0051499 TK0668 79d8d051821a7db2a8e02730865f5e42 111 Gene3D G3DSA:2.30.30.240 4 81 1.2E-5 T 31-10-2018 TK0668 79d8d051821a7db2a8e02730865f5e42 111 Pfam PF05239 PRC-barrel domain 3 82 1.4E-13 T 31-10-2018 IPR027275 PRC-barrel domain TK0668 79d8d051821a7db2a8e02730865f5e42 111 SUPERFAMILY SSF50346 4 79 3.92E-13 T 31-10-2018 IPR011033 PRC-barrel-like superfamily TK2115 195e0443bc24092145c844281c615e6e 141 Gene3D G3DSA:3.90.1170.40 1 136 1.8E-51 T 31-10-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 TK2115 195e0443bc24092145c844281c615e6e 141 Pfam PF02391 MoaE protein 5 117 6.4E-39 T 31-10-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 TK2115 195e0443bc24092145c844281c615e6e 141 SUPERFAMILY SSF54690 3 136 3.53E-47 T 31-10-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 TK1928 64ed2a768126a41f45f45e1af6614f1d 341 Gene3D G3DSA:3.40.50.11850 100 208 5.3E-40 T 31-10-2018 TK1928 64ed2a768126a41f45f45e1af6614f1d 341 Gene3D G3DSA:3.40.50.11840 5 98 1.2E-31 T 31-10-2018 TK1928 64ed2a768126a41f45f45e1af6614f1d 341 PIRSF PIRSF004967 3 335 4.2E-82 T 31-10-2018 IPR035435 Diphthamide synthesis DHP1/DPH2, eukaryotes and archaea GO:0017183 MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 TK1928 64ed2a768126a41f45f45e1af6614f1d 341 Gene3D G3DSA:3.40.50.11860 212 313 1.9E-34 T 31-10-2018 TK1928 64ed2a768126a41f45f45e1af6614f1d 341 Pfam PF01866 Putative diphthamide synthesis protein 26 318 2.7E-78 T 31-10-2018 IPR016435 Diphthamide synthesis DPH1/DPH2 MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 TK1928 64ed2a768126a41f45f45e1af6614f1d 341 TIGRFAM TIGR00322 diphth2_R: diphthamide biosynthesis enzyme Dph1/Dph2 domain 8 313 5.4E-92 T 31-10-2018 IPR016435 Diphthamide synthesis DPH1/DPH2 MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 TK1928 64ed2a768126a41f45f45e1af6614f1d 341 TIGRFAM TIGR03682 arCOG04112: diphthamide biosynthesis enzyme Dph2 17 324 8.6E-114 T 31-10-2018 IPR022428 Diphthamide synthesis Dph2, archaea GO:0017183 MetaCyc: PWY-6482|MetaCyc: PWY-7546 TK1078 3cc1376cbcbf09b3de81ccdb36f25b53 147 Pfam PF00164 Ribosomal protein S12/S23 32 146 4.8E-51 T 31-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TK1078 3cc1376cbcbf09b3de81ccdb36f25b53 147 SUPERFAMILY SSF50249 23 147 5.65E-37 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold TK1078 3cc1376cbcbf09b3de81ccdb36f25b53 147 PIRSF PIRSF002133 19 147 4.0E-37 T 31-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TK1078 3cc1376cbcbf09b3de81ccdb36f25b53 147 Hamap MF_00403_A 30S ribosomal protein S12 [rpsL]. 1 147 45.317 T 31-10-2018 IPR022863 Ribosomal protein S12, archaea TK1078 3cc1376cbcbf09b3de81ccdb36f25b53 147 TIGRFAM TIGR00982 uS12_E_A: ribosomal protein uS12 9 147 2.7E-82 T 31-10-2018 IPR005680 Ribosomal protein S23, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1078 3cc1376cbcbf09b3de81ccdb36f25b53 147 PRINTS PR01034 Ribosomal protein S12 signature 47 62 4.6E-5 T 31-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TK1078 3cc1376cbcbf09b3de81ccdb36f25b53 147 PRINTS PR01034 Ribosomal protein S12 signature 79 98 4.6E-5 T 31-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TK1078 3cc1376cbcbf09b3de81ccdb36f25b53 147 PRINTS PR01034 Ribosomal protein S12 signature 62 77 4.6E-5 T 31-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TK1078 3cc1376cbcbf09b3de81ccdb36f25b53 147 ProSitePatterns PS00055 Ribosomal protein S12 signature. 63 70 - T 31-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TK1078 3cc1376cbcbf09b3de81ccdb36f25b53 147 Gene3D G3DSA:2.40.50.140 28 147 2.3E-51 T 31-10-2018 TK0242 a1b27105feb13aa3b40b60d24abe8613 293 SUPERFAMILY SSF55681 9 254 6.84E-29 T 31-10-2018 TK0242 a1b27105feb13aa3b40b60d24abe8613 293 Pfam PF13393 Histidyl-tRNA synthetase 10 254 1.2E-20 T 31-10-2018 TK0242 a1b27105feb13aa3b40b60d24abe8613 293 Gene3D G3DSA:3.30.930.10 7 253 1.2E-28 T 31-10-2018 TK0801 68cba0cbc4a4528704a3e8af2a9820d2 258 Pfam PF01163 RIO1 family 65 246 9.4E-55 T 31-10-2018 TK0801 68cba0cbc4a4528704a3e8af2a9820d2 258 Gene3D G3DSA:3.30.200.20 51 151 2.1E-12 T 31-10-2018 TK0801 68cba0cbc4a4528704a3e8af2a9820d2 258 SMART SM00090 23 257 6.1E-119 T 31-10-2018 IPR000687 RIO kinase GO:0004674|GO:0005524 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6791226 TK0801 68cba0cbc4a4528704a3e8af2a9820d2 258 ProSitePatterns PS00109 Tyrosine protein kinases specific active-site signature. 191 203 - T 31-10-2018 IPR008266 Tyrosine-protein kinase, active site GO:0004672|GO:0006468 TK0801 68cba0cbc4a4528704a3e8af2a9820d2 258 Gene3D G3DSA:1.10.510.10 156 257 7.7E-27 T 31-10-2018 TK0801 68cba0cbc4a4528704a3e8af2a9820d2 258 SUPERFAMILY SSF56112 43 248 2.47E-22 T 31-10-2018 IPR011009 Protein kinase-like domain superfamily TK0801 68cba0cbc4a4528704a3e8af2a9820d2 258 ProSitePatterns PS01245 RIO1/ZK632.3/MJ0444 family signature. 191 202 - T 31-10-2018 IPR018935 RIO kinase, conserved site GO:0004674|GO:0005524 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6791226 TK0736 61e6b3eac9de2a6959e026b92cb47ec9 263 Gene3D G3DSA:3.40.50.720 3 258 1.0E-64 T 31-10-2018 TK0736 61e6b3eac9de2a6959e026b92cb47ec9 263 SUPERFAMILY SSF51735 8 258 9.39E-67 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily TK0736 61e6b3eac9de2a6959e026b92cb47ec9 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 3.5E-26 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TK0736 61e6b3eac9de2a6959e026b92cb47ec9 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 3.5E-26 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TK0736 61e6b3eac9de2a6959e026b92cb47ec9 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 3.5E-26 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TK0736 61e6b3eac9de2a6959e026b92cb47ec9 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 222 242 3.5E-26 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TK0736 61e6b3eac9de2a6959e026b92cb47ec9 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 3.5E-26 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TK0736 61e6b3eac9de2a6959e026b92cb47ec9 263 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 18 257 1.5E-49 T 31-10-2018 TK0202 d5fb466fc8c4a7f6f0ccf9e0064c17bc 80 Pfam PF02700 Phosphoribosylformylglycinamidine (FGAM) synthase 4 76 6.9E-26 T 31-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 TK0202 d5fb466fc8c4a7f6f0ccf9e0064c17bc 80 ProDom PD010362 PHOSPHORIBOSYLFORMYLGLYCINAMIDINE PURS SYNTHETASE SYNTHASE COMPONENT SYNTHASE LIGASE FGAM UPF0062 I 10 80 9.0E-25 T 31-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 TK0202 d5fb466fc8c4a7f6f0ccf9e0064c17bc 80 Hamap MF_01926 Phosphoribosylformylglycinamidine synthase subunit PurS [purS]. 3 76 20.237 T 31-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 TK0202 d5fb466fc8c4a7f6f0ccf9e0064c17bc 80 Gene3D G3DSA:3.30.1280.10 1 80 8.6E-28 T 31-10-2018 IPR036604 Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TK0202 d5fb466fc8c4a7f6f0ccf9e0064c17bc 80 TIGRFAM TIGR00302 TIGR00302: phosphoribosylformylglycinamidine synthase, purS protein 4 77 3.8E-24 T 31-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 TK0202 d5fb466fc8c4a7f6f0ccf9e0064c17bc 80 SUPERFAMILY SSF82697 3 78 1.45E-24 T 31-10-2018 IPR036604 Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TK0911 6d865b129a6ece3b200bbd5451d5037e 629 SUPERFAMILY SSF55931 3 453 8.5E-100 T 31-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 TK0911 6d865b129a6ece3b200bbd5451d5037e 629 Pfam PF02934 GatB/GatE catalytic domain 13 441 1.7E-64 T 31-10-2018 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 TK0911 6d865b129a6ece3b200bbd5451d5037e 629 ProDom PD609240 SUBUNIT E AMIDOTRANSFERASE 6.3.5.- LIGASE GLUTAMYL-TRNAGLN GLU-ADT BIOSYNTHESIS TRANSFERASE B 282 406 2.0E-64 T 31-10-2018 TK0911 6d865b129a6ece3b200bbd5451d5037e 629 Gene3D G3DSA:1.10.150.380 453 545 7.7E-24 T 31-10-2018 TK0911 6d865b129a6ece3b200bbd5451d5037e 629 SUPERFAMILY SSF89095 482 624 4.84E-28 T 31-10-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-like GO:0016884 TK0911 6d865b129a6ece3b200bbd5451d5037e 629 Gene3D G3DSA:3.30.1360.30 274 404 3.4E-53 T 31-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 TK0911 6d865b129a6ece3b200bbd5451d5037e 629 SUPERFAMILY SSF55261 278 404 7.03E-46 T 31-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 TK0911 6d865b129a6ece3b200bbd5451d5037e 629 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 177 191 - T 31-10-2018 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 TK0911 6d865b129a6ece3b200bbd5451d5037e 629 Pfam PF02938 GAD domain 299 390 1.7E-17 T 31-10-2018 IPR029351 GAD domain Reactome: R-HSA-379726 TK0911 6d865b129a6ece3b200bbd5451d5037e 629 Hamap MF_00588 Glutamyl-tRNA(Gln) amidotransferase subunit E [gatE]. 1 629 342.247 T 31-10-2018 IPR004414 Glutamyl-tRNA(Gln) amidotransferase subunit E GO:0016884 TK0911 6d865b129a6ece3b200bbd5451d5037e 629 Gene3D G3DSA:1.10.10.410 566 624 3.5E-13 T 31-10-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal TK0911 6d865b129a6ece3b200bbd5451d5037e 629 Pfam PF02637 GatB domain 485 624 2.5E-27 T 31-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 TK0911 6d865b129a6ece3b200bbd5451d5037e 629 SMART SM00845 484 624 5.7E-35 T 31-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 TK0911 6d865b129a6ece3b200bbd5451d5037e 629 TIGRFAM TIGR00134 gatE_arch: glutamyl-tRNA(Gln) amidotransferase, subunit E 5 627 1.4E-238 T 31-10-2018 IPR004414 Glutamyl-tRNA(Gln) amidotransferase subunit E GO:0016884 TK0514 dd0f17a2f987dd23c875b85ced5d851f 123 TIGRFAM TIGR00494 crcB: protein CrcB 8 121 2.7E-29 T 31-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 TK0514 dd0f17a2f987dd23c875b85ced5d851f 123 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 6 122 19.732 T 31-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 TK0514 dd0f17a2f987dd23c875b85ced5d851f 123 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 7 117 1.9E-25 T 31-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 TK1230 66281926e2b6c9accf77122bb94b96a7 377 SUPERFAMILY SSF53756 2 364 4.93E-122 T 31-10-2018 TK1230 66281926e2b6c9accf77122bb94b96a7 377 Gene3D G3DSA:3.40.50.2000 183 347 3.8E-134 T 31-10-2018 TK1230 66281926e2b6c9accf77122bb94b96a7 377 TIGRFAM TIGR00236 wecB: UDP-N-acetylglucosamine 2-epimerase 2 360 1.8E-130 T 31-10-2018 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 TK1230 66281926e2b6c9accf77122bb94b96a7 377 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 28 360 9.0E-119 T 31-10-2018 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 TK1230 66281926e2b6c9accf77122bb94b96a7 377 Gene3D G3DSA:3.40.50.2000 6 357 3.8E-134 T 31-10-2018 TK1405 34075baaa307be7b2df8a0df3ee627cd 623 Hamap MF_00452 Phosphoenolpyruvate carboxykinase [GTP] [pckG]. 18 605 36.545 T 31-10-2018 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 TK1405 34075baaa307be7b2df8a0df3ee627cd 623 ProSitePatterns PS00505 Phosphoenolpyruvate carboxykinase (GTP) signature. 268 276 - T 31-10-2018 IPR018091 Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site GO:0004613 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 TK1405 34075baaa307be7b2df8a0df3ee627cd 623 SUPERFAMILY SSF53795 244 604 1.33E-107 T 31-10-2018 TK1405 34075baaa307be7b2df8a0df3ee627cd 623 SUPERFAMILY SSF68923 11 243 1.67E-64 T 31-10-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 TK1405 34075baaa307be7b2df8a0df3ee627cd 623 Gene3D G3DSA:3.40.449.10 27 246 1.7E-146 T 31-10-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 TK1405 34075baaa307be7b2df8a0df3ee627cd 623 Pfam PF00821 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain 244 604 2.3E-105 T 31-10-2018 IPR035077 Phosphoenolpyruvate carboxykinase, GTP-utilising, C-terminal GO:0004611|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 TK1405 34075baaa307be7b2df8a0df3ee627cd 623 Gene3D G3DSA:2.170.8.10 65 398 1.7E-146 T 31-10-2018 TK1405 34075baaa307be7b2df8a0df3ee627cd 623 Pfam PF17297 Phosphoenolpyruvate carboxykinase N-terminal domain 29 239 6.7E-59 T 31-10-2018 IPR035078 Phosphoenolpyruvate carboxykinase, GTP-utilising, N-terminal GO:0004611|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 TK1405 34075baaa307be7b2df8a0df3ee627cd 623 Gene3D G3DSA:3.90.228.20 247 603 1.7E-146 T 31-10-2018 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 TK1405 34075baaa307be7b2df8a0df3ee627cd 623 PIRSF PIRSF001348 5 608 7.8E-212 T 31-10-2018 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 TK2197 0b0acb6233115667c3f25213639deb46 300 Gene3D G3DSA:3.40.225.10 120 298 1.5E-44 T 31-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily TK2197 0b0acb6233115667c3f25213639deb46 300 Pfam PF10120 Thiamine-phosphate synthase 132 289 2.3E-46 T 31-10-2018 IPR019293 Thiamine-phosphate synthase ThiN GO:0004789 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 TK2197 0b0acb6233115667c3f25213639deb46 300 SUPERFAMILY SSF53639 126 295 3.53E-47 T 31-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily TK2197 0b0acb6233115667c3f25213639deb46 300 Gene3D G3DSA:1.10.260.40 16 79 2.4E-7 T 31-10-2018 TK2197 0b0acb6233115667c3f25213639deb46 300 SMART SM00530 19 74 0.0028 T 31-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TK2197 0b0acb6233115667c3f25213639deb46 300 SUPERFAMILY SSF47413 17 77 7.41E-9 T 31-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TK1806 db9475b0b026362f70bd303d6b854127 233 PIRSF PIRSF006816 1 232 1.3E-75 T 31-10-2018 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 TK1806 db9475b0b026362f70bd303d6b854127 233 Gene3D G3DSA:3.40.50.80 85 196 4.5E-27 T 31-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain TK1806 db9475b0b026362f70bd303d6b854127 233 Hamap MF_01211 Dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit [pyrK]. 2 231 33.735 T 31-10-2018 IPR023455 Dihydroorotate dehydrogenase electron transfer subunit TK1806 db9475b0b026362f70bd303d6b854127 233 Pfam PF00175 Oxidoreductase NAD-binding domain 94 183 4.8E-8 T 31-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 TK1806 db9475b0b026362f70bd303d6b854127 233 SUPERFAMILY SSF52343 80 229 1.27E-31 T 31-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain TK1806 db9475b0b026362f70bd303d6b854127 233 SUPERFAMILY SSF63380 2 85 1.15E-18 T 31-10-2018 IPR017938 Riboflavin synthase-like beta-barrel TK1806 db9475b0b026362f70bd303d6b854127 233 Gene3D G3DSA:2.40.30.10 3 84 4.9E-12 T 31-10-2018 TK1806 db9475b0b026362f70bd303d6b854127 233 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 197 229 2.2E-10 T 31-10-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain TK1806 db9475b0b026362f70bd303d6b854127 233 PRINTS PR00409 Phthalate dioxygenase reductase family signature 93 112 1.8E-5 T 31-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 TK1806 db9475b0b026362f70bd303d6b854127 233 PRINTS PR00409 Phthalate dioxygenase reductase family signature 170 178 1.8E-5 T 31-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 TK1806 db9475b0b026362f70bd303d6b854127 233 PRINTS PR00409 Phthalate dioxygenase reductase family signature 118 127 1.8E-5 T 31-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 TK0964 4d5e13c0be496d1a72411a1bfc8f40bd 357 SUPERFAMILY SSF159065 1 128 1.11E-36 T 31-10-2018 IPR038069 Pelota/DOM34, N-terminal domain TK0964 4d5e13c0be496d1a72411a1bfc8f40bd 357 Gene3D G3DSA:3.30.420.60 133 257 7.2E-37 T 31-10-2018 TK0964 4d5e13c0be496d1a72411a1bfc8f40bd 357 SUPERFAMILY SSF53137 131 259 6.1E-32 T 31-10-2018 TK0964 4d5e13c0be496d1a72411a1bfc8f40bd 357 Gene3D G3DSA:3.30.1330.30 258 357 1.6E-32 T 31-10-2018 IPR029064 50S ribosomal protein L30e-like TK0964 4d5e13c0be496d1a72411a1bfc8f40bd 357 Pfam PF03465 eRF1 domain 3 261 356 3.3E-25 T 31-10-2018 IPR005142 eRF1 domain 3 TK0964 4d5e13c0be496d1a72411a1bfc8f40bd 357 Pfam PF03463 eRF1 domain 1 5 127 3.1E-29 T 31-10-2018 IPR005140 eRF1 domain 1/Pelota-like TK0964 4d5e13c0be496d1a72411a1bfc8f40bd 357 TIGRFAM TIGR00111 pelota: mRNA surveillance protein pelota 1 356 1.7E-113 T 31-10-2018 IPR004405 Translation release factor pelota GO:0070481|GO:0070966|GO:0071025 TK0964 4d5e13c0be496d1a72411a1bfc8f40bd 357 Pfam PF03464 eRF1 domain 2 136 250 1.2E-17 T 31-10-2018 IPR005141 eRF1 domain 2 TK0964 4d5e13c0be496d1a72411a1bfc8f40bd 357 Hamap MF_01853 Protein pelota homolog [pelA]. 2 356 37.419 T 31-10-2018 IPR023521 Translation release factor pelota, archaea GO:0070481|GO:0070966|GO:0071025 TK0964 4d5e13c0be496d1a72411a1bfc8f40bd 357 Gene3D G3DSA:2.30.30.870 1 130 2.4E-38 T 31-10-2018 IPR038069 Pelota/DOM34, N-terminal domain TK0964 4d5e13c0be496d1a72411a1bfc8f40bd 357 SMART SM01194 1 129 1.9E-48 T 31-10-2018 IPR005140 eRF1 domain 1/Pelota-like TK0964 4d5e13c0be496d1a72411a1bfc8f40bd 357 SUPERFAMILY SSF55315 251 356 1.88E-29 T 31-10-2018 IPR029064 50S ribosomal protein L30e-like TK1777 9e879411d70e599c9d152b396a4dee2b 450 Gene3D G3DSA:3.40.120.10 245 345 3.7E-46 T 31-10-2018 TK1777 9e879411d70e599c9d152b396a4dee2b 450 TIGRFAM TIGR03990 Arch_GlmM: phosphoglucosamine mutase 1 440 1.3E-149 T 31-10-2018 IPR024086 Phosphoglucosamine mutase, archaeal type GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TK1777 9e879411d70e599c9d152b396a4dee2b 450 SUPERFAMILY SSF53738 248 350 3.85E-10 T 31-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TK1777 9e879411d70e599c9d152b396a4dee2b 450 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 196 209 3.3E-16 T 31-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TK1777 9e879411d70e599c9d152b396a4dee2b 450 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 224 239 3.3E-16 T 31-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TK1777 9e879411d70e599c9d152b396a4dee2b 450 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 162 181 3.3E-16 T 31-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TK1777 9e879411d70e599c9d152b396a4dee2b 450 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 86 100 3.3E-16 T 31-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TK1777 9e879411d70e599c9d152b396a4dee2b 450 Gene3D G3DSA:3.30.310.50 346 450 3.5E-19 T 31-10-2018 TK1777 9e879411d70e599c9d152b396a4dee2b 450 Gene3D G3DSA:3.40.120.10 1 145 6.7E-44 T 31-10-2018 TK1777 9e879411d70e599c9d152b396a4dee2b 450 SUPERFAMILY SSF55957 343 445 3.27E-22 T 31-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TK1777 9e879411d70e599c9d152b396a4dee2b 450 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 87 96 - T 31-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TK1777 9e879411d70e599c9d152b396a4dee2b 450 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 148 244 5.9E-25 T 31-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TK1777 9e879411d70e599c9d152b396a4dee2b 450 Gene3D G3DSA:3.40.120.10 160 342 3.7E-46 T 31-10-2018 TK1777 9e879411d70e599c9d152b396a4dee2b 450 SUPERFAMILY SSF53738 2 168 2.59E-40 T 31-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TK1777 9e879411d70e599c9d152b396a4dee2b 450 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 378 435 1.2E-11 T 31-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TK1777 9e879411d70e599c9d152b396a4dee2b 450 SUPERFAMILY SSF53738 147 247 2.28E-27 T 31-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TK1777 9e879411d70e599c9d152b396a4dee2b 450 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 2 129 1.7E-37 T 31-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TK0196 0a2d0600a9a5fbf68d900f0cc519db99 331 SUPERFAMILY SSF52440 1 97 5.66E-31 T 31-10-2018 IPR016185 Pre-ATP-grasp domain superfamily TK0196 0a2d0600a9a5fbf68d900f0cc519db99 331 Gene3D G3DSA:3.30.470.20 87 329 5.5E-98 T 31-10-2018 TK0196 0a2d0600a9a5fbf68d900f0cc519db99 331 Pfam PF06849 Protein of unknown function (DUF1246) 3 117 4.1E-33 T 31-10-2018 IPR010672 IMP biosynthesis enzyme PurP, N-terminal GO:0000287|GO:0005524|GO:0006188|GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 TK0196 0a2d0600a9a5fbf68d900f0cc519db99 331 Gene3D G3DSA:3.40.50.20 1 85 1.5E-28 T 31-10-2018 TK0196 0a2d0600a9a5fbf68d900f0cc519db99 331 Pfam PF06973 Domain of unknown function (DUF1297) 149 331 3.3E-71 T 31-10-2018 IPR009720 IMP biosynthesis enzyme PurP, C-terminal GO:0000287|GO:0005524|GO:0006188|GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 TK0196 0a2d0600a9a5fbf68d900f0cc519db99 331 Gene3D G3DSA:3.30.1490.20 114 174 5.5E-98 T 31-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 TK0196 0a2d0600a9a5fbf68d900f0cc519db99 331 PIRSF PIRSF004602 1 331 3.2E-130 T 31-10-2018 IPR023656 IMP biosynthesis enzyme PurP GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 TK0196 0a2d0600a9a5fbf68d900f0cc519db99 331 SUPERFAMILY SSF56059 101 331 1.93E-78 T 31-10-2018 TK0196 0a2d0600a9a5fbf68d900f0cc519db99 331 Hamap MF_01163 5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase [purP]. 1 331 48.867 T 31-10-2018 IPR023656 IMP biosynthesis enzyme PurP GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 TK0257 2178688dab5c9feeb12814bd08571bcf 389 Gene3D G3DSA:3.40.50.1100 51 380 1.4E-189 T 31-10-2018 TK0257 2178688dab5c9feeb12814bd08571bcf 389 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 5 385 9.3E-194 T 31-10-2018 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 TK0257 2178688dab5c9feeb12814bd08571bcf 389 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 1 387 53.029 T 31-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 TK0257 2178688dab5c9feeb12814bd08571bcf 389 SUPERFAMILY SSF53686 4 384 6.68E-147 T 31-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme TK0257 2178688dab5c9feeb12814bd08571bcf 389 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 51 374 5.3E-47 T 31-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme TK0257 2178688dab5c9feeb12814bd08571bcf 389 Gene3D G3DSA:3.40.50.1100 7 203 1.4E-189 T 31-10-2018 TK0257 2178688dab5c9feeb12814bd08571bcf 389 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 78 92 - T 31-10-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 TK0257 2178688dab5c9feeb12814bd08571bcf 389 PIRSF PIRSF001413 5 389 7.2E-167 T 31-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 TK1305 b805c92c5d81382e1b732daddbc7e115 1144 Pfam PF14528 LAGLIDADG-like domain 322 390 5.2E-19 T 31-10-2018 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 TK1305 b805c92c5d81382e1b732daddbc7e115 1144 SMART SM00306 19 131 4.1E-30 T 31-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TK1305 b805c92c5d81382e1b732daddbc7e115 1144 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 567 701 3.6E-12 T 31-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 TK1305 b805c92c5d81382e1b732daddbc7e115 1144 SUPERFAMILY SSF52156 881 1007 9.81E-35 T 31-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily TK1305 b805c92c5d81382e1b732daddbc7e115 1144 Pfam PF14578 Elongation factor Tu domain 4 1014 1100 1.7E-29 T 31-10-2018 IPR029459 Elongation factor Tu-type domain TK1305 b805c92c5d81382e1b732daddbc7e115 1144 Gene3D G3DSA:3.10.28.10 227 386 1.6E-28 T 31-10-2018 IPR027434 Homing endonuclease TK1305 b805c92c5d81382e1b732daddbc7e115 1144 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 546 567 9.4E-8 T 31-10-2018 IPR030934 Intein C-terminal splicing region TK1305 b805c92c5d81382e1b732daddbc7e115 1144 Gene3D G3DSA:3.40.50.10050 896 1004 2.9E-36 T 31-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily TK1305 b805c92c5d81382e1b732daddbc7e115 1144 Pfam PF03144 Elongation factor Tu domain 2 794 872 2.2E-13 T 31-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 TK1305 b805c92c5d81382e1b732daddbc7e115 1144 Pfam PF00009 Elongation factor Tu GTP binding domain 581 761 4.4E-25 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TK1305 b805c92c5d81382e1b732daddbc7e115 1144 PRINTS PR00379 Intein signature 321 333 1.7E-11 T 31-10-2018 IPR006142 Intein GO:0016539 TK1305 b805c92c5d81382e1b732daddbc7e115 1144 PRINTS PR00379 Intein signature 544 561 1.7E-11 T 31-10-2018 IPR006142 Intein GO:0016539 TK1305 b805c92c5d81382e1b732daddbc7e115 1144 PRINTS PR00379 Intein signature 98 111 1.7E-11 T 31-10-2018 IPR006142 Intein GO:0016539 TK1305 b805c92c5d81382e1b732daddbc7e115 1144 PRINTS PR00379 Intein signature 229 241 1.7E-11 T 31-10-2018 IPR006142 Intein GO:0016539 TK1305 b805c92c5d81382e1b732daddbc7e115 1144 PRINTS PR00379 Intein signature 349 364 1.7E-11 T 31-10-2018 IPR006142 Intein GO:0016539 TK1305 b805c92c5d81382e1b732daddbc7e115 1144 SUPERFAMILY SSF55608 304 405 1.62E-20 T 31-10-2018 IPR027434 Homing endonuclease TK1305 b805c92c5d81382e1b732daddbc7e115 1144 Pfam PF14890 Intein splicing domain 81 566 7.8E-31 T 31-10-2018 TK1305 b805c92c5d81382e1b732daddbc7e115 1144 TIGRFAM TIGR00491 aIF-2: translation initiation factor aIF-2 4 1141 9.2E-245 T 31-10-2018 IPR004544 Translation initiation factor aIF-2, archaea GO:0003743|GO:0005525|GO:0005622|GO:0006413 TK1305 b805c92c5d81382e1b732daddbc7e115 1144 TIGRFAM TIGR01445 intein_Nterm: intein N-terminal splicing region 21 111 3.8E-16 T 31-10-2018 IPR006141 Intein N-terminal splicing region GO:0016539 Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TK1305 b805c92c5d81382e1b732daddbc7e115 1144 Gene3D G3DSA:3.40.50.300 568 774 1.1E-52 T 31-10-2018 TK1305 b805c92c5d81382e1b732daddbc7e115 1144 Gene3D G3DSA:2.40.30.10 1013 1103 9.7E-31 T 31-10-2018 TK1305 b805c92c5d81382e1b732daddbc7e115 1144 SUPERFAMILY SSF50447 1012 1139 6.28E-26 T 31-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily TK1305 b805c92c5d81382e1b732daddbc7e115 1144 Gene3D G3DSA:2.170.16.10 18 200 3.8E-16 T 31-10-2018 TK1305 b805c92c5d81382e1b732daddbc7e115 1144 Gene3D G3DSA:2.40.30.10 775 885 4.1E-41 T 31-10-2018 TK1305 b805c92c5d81382e1b732daddbc7e115 1144 SMART SM00305 527 572 7.7E-15 T 31-10-2018 IPR003586 Hint domain C-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TK1305 b805c92c5d81382e1b732daddbc7e115 1144 SUPERFAMILY SSF52540 567 835 5.13E-45 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK1305 b805c92c5d81382e1b732daddbc7e115 1144 Hamap MF_00100_A Translation initiation factor IF-2 [infB]. 549 1143 41.867 T 31-10-2018 IPR004544 Translation initiation factor aIF-2, archaea GO:0003743|GO:0005525|GO:0005622|GO:0006413 TK1305 b805c92c5d81382e1b732daddbc7e115 1144 Gene3D G3DSA:2.170.16.10 507 567 2.0E-8 T 31-10-2018 TK1305 b805c92c5d81382e1b732daddbc7e115 1144 SUPERFAMILY SSF51294 20 566 2.16E-41 T 31-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TK1305 b805c92c5d81382e1b732daddbc7e115 1144 Pfam PF11987 Translation-initiation factor 2 898 993 5.2E-23 T 31-10-2018 IPR023115 Translation initiation factor IF- 2, domain 3 TK0928 8c86ecf0696b6442c2f66e82fc9614c3 461 SMART SM00490 328 406 6.0E-13 T 31-10-2018 IPR001650 Helicase, C-terminal TK0928 8c86ecf0696b6442c2f66e82fc9614c3 461 Pfam PF00271 Helicase conserved C-terminal domain 304 404 4.9E-12 T 31-10-2018 IPR001650 Helicase, C-terminal TK0928 8c86ecf0696b6442c2f66e82fc9614c3 461 Pfam PF04851 Type III restriction enzyme, res subunit 92 231 2.0E-17 T 31-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 TK0928 8c86ecf0696b6442c2f66e82fc9614c3 461 SUPERFAMILY SSF52540 26 209 1.07E-16 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK0928 8c86ecf0696b6442c2f66e82fc9614c3 461 Gene3D G3DSA:3.40.50.300 273 457 1.0E-34 T 31-10-2018 TK0928 8c86ecf0696b6442c2f66e82fc9614c3 461 Gene3D G3DSA:3.40.50.300 84 261 2.4E-35 T 31-10-2018 TK0928 8c86ecf0696b6442c2f66e82fc9614c3 461 SMART SM00487 91 272 4.5E-27 T 31-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TK0928 8c86ecf0696b6442c2f66e82fc9614c3 461 SUPERFAMILY SSF52540 136 419 4.07E-36 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK1603 b7cbdb38d44e85297d6dab7d1b09df59 465 Gene3D G3DSA:3.40.50.12240 4 461 7.4E-196 T 31-10-2018 TK1603 b7cbdb38d44e85297d6dab7d1b09df59 465 SUPERFAMILY SSF52540 81 357 3.59E-89 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK1603 b7cbdb38d44e85297d6dab7d1b09df59 465 TIGRFAM TIGR01041 ATP_syn_B_arch: ATP synthase archaeal, B subunit 7 463 3.2E-268 T 31-10-2018 IPR005724 ATPase, A1 complex, beta subunit GO:0015986|GO:0033178|GO:0046933 TK1603 b7cbdb38d44e85297d6dab7d1b09df59 465 Hamap MF_00310 V-type ATP synthase beta chain [atpB]. 5 461 62.605 T 31-10-2018 IPR022879 V-type ATP synthase regulatory subunit B/beta Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TK1603 b7cbdb38d44e85297d6dab7d1b09df59 465 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 343 352 - T 31-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TK1603 b7cbdb38d44e85297d6dab7d1b09df59 465 SUPERFAMILY SSF50615 7 68 8.63E-5 T 31-10-2018 IPR036121 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TK1603 b7cbdb38d44e85297d6dab7d1b09df59 465 PIRSF PIRSF039114 1 465 1.2E-256 T 31-10-2018 IPR022879 V-type ATP synthase regulatory subunit B/beta Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TK1603 b7cbdb38d44e85297d6dab7d1b09df59 465 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 11 77 2.8E-13 T 31-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TK1603 b7cbdb38d44e85297d6dab7d1b09df59 465 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 134 352 7.6E-69 T 31-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TK1603 b7cbdb38d44e85297d6dab7d1b09df59 465 SUPERFAMILY SSF47917 365 422 2.51E-9 T 31-10-2018 TK0779 04aca868d05000d173f983cc4d7dbea3 237 Gene3D G3DSA:2.40.50.580 5 81 2.3E-25 T 31-10-2018 TK0779 04aca868d05000d173f983cc4d7dbea3 237 Hamap MF_00095 Sugar fermentation stimulation protein A [sfsA]. 5 236 39.163 T 31-10-2018 IPR005224 Sugar fermentation stimulation protein TK0779 04aca868d05000d173f983cc4d7dbea3 237 TIGRFAM TIGR00230 sfsA: sugar fermentation stimulation protein 10 235 2.6E-53 T 31-10-2018 IPR005224 Sugar fermentation stimulation protein TK0779 04aca868d05000d173f983cc4d7dbea3 237 Pfam PF03749 Sugar fermentation stimulation protein 17 224 7.7E-50 T 31-10-2018 IPR005224 Sugar fermentation stimulation protein TK0779 04aca868d05000d173f983cc4d7dbea3 237 Gene3D G3DSA:3.40.1350.60 82 237 2.2E-41 T 31-10-2018 TK1850 0e77390fa31b4ca83a8cba2f77c175a0 159 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 3 148 4.1E-23 T 31-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain TK1850 0e77390fa31b4ca83a8cba2f77c175a0 159 SUPERFAMILY SSF54534 2 151 7.46E-50 T 31-10-2018 TK1850 0e77390fa31b4ca83a8cba2f77c175a0 159 Gene3D G3DSA:3.10.50.80 2 158 1.4E-55 T 31-10-2018 TK1544 60b41c9f1df7183b8f6b7e17a634a006 458 Pfam PF03008 Archaea bacterial proteins of unknown function 303 401 2.4E-30 T 31-10-2018 IPR004256 Domain of unknown function DUF234, DEXX-box ATPase C-terminal TK1544 60b41c9f1df7183b8f6b7e17a634a006 458 SUPERFAMILY SSF46785 233 312 7.94E-6 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TK1544 60b41c9f1df7183b8f6b7e17a634a006 458 Gene3D G3DSA:3.40.50.300 2 165 9.2E-31 T 31-10-2018 TK1544 60b41c9f1df7183b8f6b7e17a634a006 458 Pfam PF01637 ATPase domain predominantly from Archaea 5 182 9.3E-22 T 31-10-2018 IPR011579 ATPase domain GO:0005524 TK1544 60b41c9f1df7183b8f6b7e17a634a006 458 SUPERFAMILY SSF52540 3 236 4.46E-34 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK0875 161ee60f775f5dc40f163d45f4eb4fad 363 SUPERFAMILY SSF51735 1 169 1.28E-20 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily TK0875 161ee60f775f5dc40f163d45f4eb4fad 363 Pfam PF03435 Saccharopine dehydrogenase NADP binding domain 3 113 1.5E-17 T 31-10-2018 IPR005097 Saccharopine dehydrogenase, NADP binding domain GO:0016491|GO:0055114 TK0875 161ee60f775f5dc40f163d45f4eb4fad 363 Gene3D G3DSA:3.40.50.720 2 349 1.1E-130 T 31-10-2018 TK0875 161ee60f775f5dc40f163d45f4eb4fad 363 SUPERFAMILY SSF55347 118 252 5.17E-41 T 31-10-2018 TK0875 161ee60f775f5dc40f163d45f4eb4fad 363 Gene3D G3DSA:3.30.360.10 118 299 1.1E-130 T 31-10-2018 TK0875 161ee60f775f5dc40f163d45f4eb4fad 363 Pfam PF16653 Saccharopine dehydrogenase C-terminal domain 117 349 4.9E-31 T 31-10-2018 IPR032095 Saccharopine dehydrogenase, C-terminal Reactome: R-HSA-71064 TK0901 47a44fae4a707b7676dfbf47eac4682f 115 Gene3D G3DSA:1.10.150.80 55 115 2.0E-27 T 31-10-2018 TK0901 47a44fae4a707b7676dfbf47eac4682f 115 SUPERFAMILY SSF47819 1 113 1.66E-25 T 31-10-2018 IPR010997 HRDC-like superfamily GO:0000166|GO:0003824|GO:0044237 TK0901 47a44fae4a707b7676dfbf47eac4682f 115 Pfam PF03874 RNA polymerase Rpb4 12 113 5.0E-6 T 31-10-2018 IPR005574 RNA polymerase subunit RPB4/RPC9 GO:0006352|GO:0030880 TK0901 47a44fae4a707b7676dfbf47eac4682f 115 Gene3D G3DSA:1.10.287.420 1 54 3.0E-38 T 31-10-2018 TK0901 47a44fae4a707b7676dfbf47eac4682f 115 PIRSF PIRSF005053 1 115 8.2E-32 T 31-10-2018 IPR010924 DNA-directed RNA polymerase subunit F (Rpo4) TK0129 861097edecf644f0848af2f49a926c79 138 Pfam PF04009 Protein of unknown function (DUF356) 5 110 1.1E-35 T 31-10-2018 IPR007154 Protein of unknown function DUF356 TK0129 861097edecf644f0848af2f49a926c79 138 PIRSF PIRSF006606 3 134 8.0E-43 T 31-10-2018 IPR007154 Protein of unknown function DUF356 TK1130 8fe6d114123319116aa22a21cb1d6d5e 396 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 294 388 1.7E-18 T 31-10-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II TK1130 8fe6d114123319116aa22a21cb1d6d5e 396 Gene3D G3DSA:3.40.50.970 10 211 1.6E-77 T 31-10-2018 TK1130 8fe6d114123319116aa22a21cb1d6d5e 396 SUPERFAMILY SSF52518 23 277 2.16E-67 T 31-10-2018 IPR029061 Thiamin diphosphate-binding fold TK1130 8fe6d114123319116aa22a21cb1d6d5e 396 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 34 270 7.8E-76 T 31-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 TK1130 8fe6d114123319116aa22a21cb1d6d5e 396 Gene3D G3DSA:3.40.50.920 282 395 3.3E-23 T 31-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TK1130 8fe6d114123319116aa22a21cb1d6d5e 396 SUPERFAMILY SSF52922 286 393 6.14E-24 T 31-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TK0541 0cfb8a59eaf212c2d45b53640b5fb96c 396 Pfam PF00994 Probable molybdopterin binding domain 186 315 2.7E-17 T 31-10-2018 IPR001453 MoaB/Mog domain TK0541 0cfb8a59eaf212c2d45b53640b5fb96c 396 SUPERFAMILY SSF63867 327 396 5.63E-20 T 31-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TK0541 0cfb8a59eaf212c2d45b53640b5fb96c 396 SUPERFAMILY SSF53218 181 322 1.14E-33 T 31-10-2018 IPR036425 MoaB/Mog-like domain superfamily TK0541 0cfb8a59eaf212c2d45b53640b5fb96c 396 Pfam PF03454 MoeA C-terminal region (domain IV) 329 395 9.1E-18 T 31-10-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TK0541 0cfb8a59eaf212c2d45b53640b5fb96c 396 Gene3D G3DSA:3.90.105.10 27 181 2.1E-110 T 31-10-2018 TK0541 0cfb8a59eaf212c2d45b53640b5fb96c 396 SMART SM00852 186 317 2.7E-26 T 31-10-2018 IPR001453 MoaB/Mog domain TK0541 0cfb8a59eaf212c2d45b53640b5fb96c 396 Pfam PF03453 MoeA N-terminal region (domain I and II) 9 173 2.1E-46 T 31-10-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TK0541 0cfb8a59eaf212c2d45b53640b5fb96c 396 Gene3D G3DSA:2.40.340.10 320 396 1.3E-28 T 31-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TK0541 0cfb8a59eaf212c2d45b53640b5fb96c 396 Gene3D G3DSA:3.40.980.10 19 314 2.1E-110 T 31-10-2018 IPR036425 MoaB/Mog-like domain superfamily TK0541 0cfb8a59eaf212c2d45b53640b5fb96c 396 SUPERFAMILY SSF63882 7 181 4.32E-59 T 31-10-2018 IPR036135 MoeA, N-terminal and linker domain superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TK0541 0cfb8a59eaf212c2d45b53640b5fb96c 396 Gene3D G3DSA:2.170.190.11 50 148 2.1E-110 T 31-10-2018 TK1974 b77b0442aff878016ab55e9528dc1854 118 SUPERFAMILY SSF69118 11 109 2.22E-27 T 31-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 TK1974 b77b0442aff878016ab55e9528dc1854 118 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 43 86 8.4E-12 T 31-10-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 TK1974 b77b0442aff878016ab55e9528dc1854 118 Gene3D G3DSA:1.20.1290.10 2 114 1.4E-29 T 31-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 TK1974 b77b0442aff878016ab55e9528dc1854 118 Pfam PF02627 Carboxymuconolactone decarboxylase family 29 107 4.1E-19 T 31-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 TK0181 38025c9fc0db5d21dd46d03fbefa2ba3 350 SUPERFAMILY SSF53901 175 348 1.23E-45 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 TK0181 38025c9fc0db5d21dd46d03fbefa2ba3 350 TIGRFAM TIGR00748 HMG_CoA_syn_Arc: putative hydroxymethylglutaryl-CoA synthase 11 349 1.6E-190 T 31-10-2018 IPR004656 Putative condensing enzyme FabH-related TK0181 38025c9fc0db5d21dd46d03fbefa2ba3 350 SUPERFAMILY SSF53901 11 169 6.55E-31 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 TK0181 38025c9fc0db5d21dd46d03fbefa2ba3 350 Hamap MF_01409 UPF0219 protein . 10 350 60.732 T 31-10-2018 IPR004656 Putative condensing enzyme FabH-related TK0181 38025c9fc0db5d21dd46d03fbefa2ba3 350 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 223 303 4.6E-10 T 31-10-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 TK0181 38025c9fc0db5d21dd46d03fbefa2ba3 350 Gene3D G3DSA:3.40.47.10 8 348 5.1E-69 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 TK1612 43dd669198e2dd53165788c516780cb5 952 SUPERFAMILY SSF53706 703 943 7.59E-16 T 31-10-2018 TK1612 43dd669198e2dd53165788c516780cb5 952 SUPERFAMILY SSF51971 187 429 7.06E-75 T 31-10-2018 TK1612 43dd669198e2dd53165788c516780cb5 952 Gene3D G3DSA:3.50.50.60 192 488 1.0E-71 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TK1612 43dd669198e2dd53165788c516780cb5 952 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 189 482 5.8E-41 T 31-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TK1612 43dd669198e2dd53165788c516780cb5 952 SUPERFAMILY SSF54862 580 694 8.79E-19 T 31-10-2018 TK1612 43dd669198e2dd53165788c516780cb5 952 Gene3D G3DSA:3.30.70.20 613 694 3.5E-14 T 31-10-2018 TK1612 43dd669198e2dd53165788c516780cb5 952 Gene3D G3DSA:3.50.50.60 287 428 1.0E-71 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TK1612 43dd669198e2dd53165788c516780cb5 952 Gene3D G3DSA:2.20.25.90 706 756 3.3E-5 T 31-10-2018 TK1612 43dd669198e2dd53165788c516780cb5 952 SUPERFAMILY SSF54292 2 97 4.36E-20 T 31-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 TK1612 43dd669198e2dd53165788c516780cb5 952 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 98 176 1.4E-18 T 31-10-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 TK1612 43dd669198e2dd53165788c516780cb5 952 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 2 74 3.0E-7 T 31-10-2018 TK1612 43dd669198e2dd53165788c516780cb5 952 PRINTS PR00419 Adrenodoxin reductase family signature 213 226 4.0E-23 T 31-10-2018 TK1612 43dd669198e2dd53165788c516780cb5 952 PRINTS PR00419 Adrenodoxin reductase family signature 255 265 4.0E-23 T 31-10-2018 TK1612 43dd669198e2dd53165788c516780cb5 952 PRINTS PR00419 Adrenodoxin reductase family signature 190 212 4.0E-23 T 31-10-2018 TK1612 43dd669198e2dd53165788c516780cb5 952 PRINTS PR00419 Adrenodoxin reductase family signature 354 367 4.0E-23 T 31-10-2018 TK1612 43dd669198e2dd53165788c516780cb5 952 PRINTS PR00419 Adrenodoxin reductase family signature 321 335 4.0E-23 T 31-10-2018 TK1612 43dd669198e2dd53165788c516780cb5 952 SUPERFAMILY SSF46548 96 199 1.41E-21 T 31-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 TK1612 43dd669198e2dd53165788c516780cb5 952 ProSitePatterns PS00641 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. 31 48 - T 31-10-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TK1612 43dd669198e2dd53165788c516780cb5 952 Gene3D G3DSA:1.10.1060.10 90 186 7.2E-25 T 31-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 TK2293 4dbca821526800035d0d40eb6a11ac01 143 Pfam PF04027 Domain of unknown function (DUF371) 6 137 9.9E-51 T 31-10-2018 IPR007171 Protein of unknown function DUF371 TK2293 4dbca821526800035d0d40eb6a11ac01 143 Gene3D G3DSA:2.60.120.630 1 142 5.0E-53 T 31-10-2018 IPR023131 Mth639-like domain superfamily TK0784 78255a4b44a473b3fcca5a951b30aa80 637 TIGRFAM TIGR00604 rad3: DNA repair helicase (rad3) 322 626 1.6E-80 T 31-10-2018 IPR013020 ATP-dependent helicase Rad3/Chl1-like GO:0004003 TK0784 78255a4b44a473b3fcca5a951b30aa80 637 Pfam PF06733 DEAD_2 62 233 1.1E-33 T 31-10-2018 IPR010614 DEAD2 GO:0003677|GO:0004003|GO:0005524 TK0784 78255a4b44a473b3fcca5a951b30aa80 637 Gene3D G3DSA:3.40.50.300 18 397 4.4E-116 T 31-10-2018 TK0784 78255a4b44a473b3fcca5a951b30aa80 637 Pfam PF13307 Helicase C-terminal domain 442 615 2.9E-37 T 31-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 TK0784 78255a4b44a473b3fcca5a951b30aa80 637 Pfam PF06777 Helical and beta-bridge domain 238 429 1.5E-65 T 31-10-2018 IPR010643 Helical and beta-bridge domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167246|Reactome: R-HSA-2564830|Reactome: R-HSA-427413|Reactome: R-HSA-5696395|Reactome: R-HSA-5696400|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73863|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-77075 TK0784 78255a4b44a473b3fcca5a951b30aa80 637 SMART SM00487 6 277 4.5E-6 T 31-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TK0784 78255a4b44a473b3fcca5a951b30aa80 637 Gene3D G3DSA:1.10.30.20 93 169 4.4E-116 T 31-10-2018 TK0784 78255a4b44a473b3fcca5a951b30aa80 637 SUPERFAMILY SSF52540 4 226 1.25E-16 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK0784 78255a4b44a473b3fcca5a951b30aa80 637 SMART SM00488 1 269 7.2E-75 T 31-10-2018 IPR006554 Helicase-like, DEXD box c2 type GO:0004003|GO:0016818 TK0784 78255a4b44a473b3fcca5a951b30aa80 637 SUPERFAMILY SSF52540 22 596 3.26E-12 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK0784 78255a4b44a473b3fcca5a951b30aa80 637 Gene3D G3DSA:1.10.275.40 228 365 4.4E-116 T 31-10-2018 TK0784 78255a4b44a473b3fcca5a951b30aa80 637 Gene3D G3DSA:3.40.50.300 412 626 1.5E-43 T 31-10-2018 TK0784 78255a4b44a473b3fcca5a951b30aa80 637 SMART SM00491 460 602 8.1E-45 T 31-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 TK1602 205a4ea18fbb3e693ed60fe44d27b5e2 585 Gene3D G3DSA:2.40.30.20 1 69 7.3E-30 T 31-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TK1602 205a4ea18fbb3e693ed60fe44d27b5e2 585 SUPERFAMILY SSF47917 447 551 9.16E-27 T 31-10-2018 TK1602 205a4ea18fbb3e693ed60fe44d27b5e2 585 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 4 66 6.4E-15 T 31-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TK1602 205a4ea18fbb3e693ed60fe44d27b5e2 585 Gene3D G3DSA:3.40.50.300 70 434 7.4E-186 T 31-10-2018 TK1602 205a4ea18fbb3e693ed60fe44d27b5e2 585 Hamap MF_00309 V-type ATP synthase alpha chain [atpA]. 1 583 54.934 T 31-10-2018 IPR022878 V-type ATP synthase catalytic alpha chain GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TK1602 205a4ea18fbb3e693ed60fe44d27b5e2 585 Pfam PF16886 ATPsynthase alpha/beta subunit N-term extension 82 202 2.1E-48 T 31-10-2018 IPR031686 ATPsynthase alpha/beta subunit, N-terminal extension KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TK1602 205a4ea18fbb3e693ed60fe44d27b5e2 585 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 425 434 - T 31-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TK1602 205a4ea18fbb3e693ed60fe44d27b5e2 585 SUPERFAMILY SSF52540 163 440 1.98E-85 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK1602 205a4ea18fbb3e693ed60fe44d27b5e2 585 SUPERFAMILY SSF50615 1 68 1.18E-13 T 31-10-2018 IPR036121 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TK1602 205a4ea18fbb3e693ed60fe44d27b5e2 585 SMART SM00382 223 411 0.0016 T 31-10-2018 IPR003593 AAA+ ATPase domain TK1602 205a4ea18fbb3e693ed60fe44d27b5e2 585 TIGRFAM TIGR01043 ATP_syn_A_arch: ATP synthase archaeal, A subunit 1 580 0.0 T 31-10-2018 IPR005726 ATP synthase alpha chain, archaea GO:0015986|GO:0033178|GO:0046961 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TK1602 205a4ea18fbb3e693ed60fe44d27b5e2 585 Gene3D G3DSA:1.10.1140.10 435 585 1.6E-60 T 31-10-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TK1602 205a4ea18fbb3e693ed60fe44d27b5e2 585 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 211 434 7.8E-93 T 31-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TK1602 205a4ea18fbb3e693ed60fe44d27b5e2 585 Gene3D G3DSA:2.40.50.100 113 184 7.4E-186 T 31-10-2018 TK0978 3b7b6e97b5b642040b042d1b5913ca01 570 Pfam PF03129 Anticodon binding domain 475 565 4.1E-23 T 31-10-2018 IPR004154 Anticodon-binding TK0978 3b7b6e97b5b642040b042d1b5913ca01 570 Gene3D G3DSA:3.30.930.10 14 458 7.7E-142 T 31-10-2018 TK0978 3b7b6e97b5b642040b042d1b5913ca01 570 Hamap MF_00253_A Glycine--tRNA ligase [glyQS]. 6 568 47.111 T 31-10-2018 IPR022960 Glycine-tRNA ligase, archaeal GO:0004820 KEGG: 00970+6.1.1.14 TK0978 3b7b6e97b5b642040b042d1b5913ca01 570 TIGRFAM TIGR00389 glyS_dimeric: glycine--tRNA ligase 8 565 2.4E-218 T 31-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 TK0978 3b7b6e97b5b642040b042d1b5913ca01 570 Gene3D G3DSA:1.10.30.30 363 426 7.7E-142 T 31-10-2018 TK0978 3b7b6e97b5b642040b042d1b5913ca01 570 SUPERFAMILY SSF52954 462 567 1.1E-31 T 31-10-2018 TK0978 3b7b6e97b5b642040b042d1b5913ca01 570 Gene3D G3DSA:1.20.1430.20 84 147 7.7E-142 T 31-10-2018 TK0978 3b7b6e97b5b642040b042d1b5913ca01 570 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 158 341 7.0E-11 T 31-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 TK0978 3b7b6e97b5b642040b042d1b5913ca01 570 Gene3D G3DSA:3.40.50.800 473 570 3.5E-32 T 31-10-2018 IPR036621 Anticodon-binding domain superfamily TK0978 3b7b6e97b5b642040b042d1b5913ca01 570 PRINTS PR01043 Glycyl-tRNA synthetase signature 27 41 1.6E-56 T 31-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 TK0978 3b7b6e97b5b642040b042d1b5913ca01 570 PRINTS PR01043 Glycyl-tRNA synthetase signature 435 447 1.6E-56 T 31-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 TK0978 3b7b6e97b5b642040b042d1b5913ca01 570 PRINTS PR01043 Glycyl-tRNA synthetase signature 513 532 1.6E-56 T 31-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 TK0978 3b7b6e97b5b642040b042d1b5913ca01 570 PRINTS PR01043 Glycyl-tRNA synthetase signature 193 210 1.6E-56 T 31-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 TK0978 3b7b6e97b5b642040b042d1b5913ca01 570 PRINTS PR01043 Glycyl-tRNA synthetase signature 210 220 1.6E-56 T 31-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 TK0978 3b7b6e97b5b642040b042d1b5913ca01 570 PRINTS PR01043 Glycyl-tRNA synthetase signature 142 154 1.6E-56 T 31-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 TK0978 3b7b6e97b5b642040b042d1b5913ca01 570 PRINTS PR01043 Glycyl-tRNA synthetase signature 161 178 1.6E-56 T 31-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 TK0978 3b7b6e97b5b642040b042d1b5913ca01 570 SUPERFAMILY SSF55681 7 478 7.21E-117 T 31-10-2018 TK1254 350047efb87e5123e6a5da5c9e9990bc 200 SMART SM01397 8 198 1.0E-100 T 31-10-2018 IPR001593 Ribosomal protein S3Ae GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1254 350047efb87e5123e6a5da5c9e9990bc 200 Hamap MF_00359 30S ribosomal protein S3Ae [rps3ae]. 8 198 36.888 T 31-10-2018 IPR030838 30S ribosomal protein S3Ae GO:0003735|GO:0005840|GO:0006412 TK1254 350047efb87e5123e6a5da5c9e9990bc 200 Pfam PF01015 Ribosomal S3Ae family 11 198 2.5E-66 T 31-10-2018 IPR001593 Ribosomal protein S3Ae GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1254 350047efb87e5123e6a5da5c9e9990bc 200 ProSitePatterns PS01191 Ribosomal protein S3Ae signature. 47 59 - T 31-10-2018 IPR018281 Ribosomal protein S3Ae, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1177 603a8fb40375d0abb6e3cdea0c72624d 346 SUPERFAMILY SSF101821 68 176 2.59E-27 T 31-10-2018 TK1177 603a8fb40375d0abb6e3cdea0c72624d 346 PIRSF PIRSF001123 1 345 5.0E-102 T 31-10-2018 IPR008007 Peptidase M42 TK1177 603a8fb40375d0abb6e3cdea0c72624d 346 Gene3D G3DSA:3.40.630.10 7 333 1.1E-130 T 31-10-2018 TK1177 603a8fb40375d0abb6e3cdea0c72624d 346 Gene3D G3DSA:2.40.30.40 68 160 1.1E-130 T 31-10-2018 IPR023367 Peptidase M42, domain 2 TK1177 603a8fb40375d0abb6e3cdea0c72624d 346 SUPERFAMILY SSF53187 4 340 2.66E-61 T 31-10-2018 TK1177 603a8fb40375d0abb6e3cdea0c72624d 346 Pfam PF05343 M42 glutamyl aminopeptidase 45 330 6.2E-97 T 31-10-2018 IPR008007 Peptidase M42 TK0341 68cca2376c66f58b0fce85fd054f96a0 202 Gene3D G3DSA:1.10.10.10 1 67 3.5E-6 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TK0341 68cca2376c66f58b0fce85fd054f96a0 202 Gene3D G3DSA:3.30.460.10 68 169 7.9E-14 T 31-10-2018 TK0341 68cca2376c66f58b0fce85fd054f96a0 202 SUPERFAMILY SSF81301 87 175 1.2E-14 T 31-10-2018 TK0341 68cca2376c66f58b0fce85fd054f96a0 202 SUPERFAMILY SSF46785 3 76 1.4E-7 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TK0341 68cca2376c66f58b0fce85fd054f96a0 202 Pfam PF01909 Nucleotidyltransferase domain 83 150 2.0E-9 T 31-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 TK0914 fecc95e13daa189b710d70a271d1f72c 408 Pfam PF00368 Hydroxymethylglutaryl-coenzyme A reductase 32 408 1.8E-140 T 31-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 TK0914 fecc95e13daa189b710d70a271d1f72c 408 SUPERFAMILY SSF55035 129 244 3.53E-40 T 31-10-2018 IPR009023 Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain superfamily GO:0050662 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 TK0914 fecc95e13daa189b710d70a271d1f72c 408 SUPERFAMILY SSF56542 4 398 1.96E-93 T 31-10-2018 IPR009029 Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding domain superfamily GO:0015936|GO:0016616|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 TK0914 fecc95e13daa189b710d70a271d1f72c 408 ProSitePatterns PS00318 Hydroxymethylglutaryl-coenzyme A reductases signature 2. 340 347 - T 31-10-2018 IPR023076 Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 TK0914 fecc95e13daa189b710d70a271d1f72c 408 TIGRFAM TIGR00533 HMG_CoA_R_NADP: hydroxymethylglutaryl-CoA reductase (NADPH) 1 408 2.5E-168 T 31-10-2018 IPR004554 Hydroxymethylglutaryl-CoA reductase, eukaryotic/archaeal type GO:0004420|GO:0008299|GO:0016021|GO:0050661|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 TK0914 fecc95e13daa189b710d70a271d1f72c 408 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 276 302 2.5E-59 T 31-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 TK0914 fecc95e13daa189b710d70a271d1f72c 408 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 64 85 2.5E-59 T 31-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 TK0914 fecc95e13daa189b710d70a271d1f72c 408 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 95 115 2.5E-59 T 31-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 TK0914 fecc95e13daa189b710d70a271d1f72c 408 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 328 349 2.5E-59 T 31-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 TK0914 fecc95e13daa189b710d70a271d1f72c 408 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 185 203 2.5E-59 T 31-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 TK0914 fecc95e13daa189b710d70a271d1f72c 408 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 225 250 2.5E-59 T 31-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 TK0914 fecc95e13daa189b710d70a271d1f72c 408 Gene3D G3DSA:3.30.70.420 129 244 3.8E-133 T 31-10-2018 IPR009023 Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain superfamily GO:0050662 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 TK0914 fecc95e13daa189b710d70a271d1f72c 408 ProSitePatterns PS00066 Hydroxymethylglutaryl-coenzyme A reductases signature 1. 187 201 - T 31-10-2018 IPR023076 Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 TK0914 fecc95e13daa189b710d70a271d1f72c 408 Gene3D G3DSA:3.90.770.10 75 395 3.8E-133 T 31-10-2018 IPR023074 Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic domain superfamily GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 TK0914 fecc95e13daa189b710d70a271d1f72c 408 Gene3D G3DSA:1.10.3270.10 1 74 9.9E-8 T 31-10-2018 IPR023282 Hydroxymethylglutaryl-CoA reductase, N-terminal GO:0004420 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 TK1595 e81315f7fc7d79999653328328940901 229 Pfam PF02254 TrkA-N domain 3 124 2.9E-29 T 31-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 TK1595 e81315f7fc7d79999653328328940901 229 Gene3D G3DSA:3.30.70.1450 141 224 6.3E-18 T 31-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 TK1595 e81315f7fc7d79999653328328940901 229 PRINTS PR00335 TrkA potassium uptake protein signature 19 33 1.8E-12 T 31-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 TK1595 e81315f7fc7d79999653328328940901 229 PRINTS PR00335 TrkA potassium uptake protein signature 49 59 1.8E-12 T 31-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 TK1595 e81315f7fc7d79999653328328940901 229 PRINTS PR00335 TrkA potassium uptake protein signature 60 70 1.8E-12 T 31-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 TK1595 e81315f7fc7d79999653328328940901 229 PRINTS PR00335 TrkA potassium uptake protein signature 2 16 1.8E-12 T 31-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 TK1595 e81315f7fc7d79999653328328940901 229 PRINTS PR00335 TrkA potassium uptake protein signature 73 87 1.8E-12 T 31-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 TK1595 e81315f7fc7d79999653328328940901 229 SUPERFAMILY SSF51735 1 144 5.07E-38 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily TK1595 e81315f7fc7d79999653328328940901 229 SUPERFAMILY SSF116726 135 221 3.66E-14 T 31-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 TK1595 e81315f7fc7d79999653328328940901 229 Pfam PF02080 TrkA-C domain 153 221 4.3E-16 T 31-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 TK1595 e81315f7fc7d79999653328328940901 229 Gene3D G3DSA:3.40.50.720 1 140 2.7E-41 T 31-10-2018 TK1795 209dee9e47b85807c4f4e09e8c944140 135 Pfam PF01886 Protein of unknown function DUF61 6 132 4.3E-37 T 31-10-2018 IPR002746 Uncharacterised protein family UPF0216 TK1795 209dee9e47b85807c4f4e09e8c944140 135 ProDom PD016056 UPF0216 PYRAB16100 PH0358 MTH949 MK1676 AF0460 PF0452 MJ1224 8 110 5.0E-53 T 31-10-2018 IPR002746 Uncharacterised protein family UPF0216 TK1795 209dee9e47b85807c4f4e09e8c944140 135 PIRSF PIRSF005264 1 135 1.1E-41 T 31-10-2018 IPR002746 Uncharacterised protein family UPF0216 TK1795 209dee9e47b85807c4f4e09e8c944140 135 Hamap MF_00585 UPF0216 protein . 4 135 26.32 T 31-10-2018 IPR002746 Uncharacterised protein family UPF0216 TK1339 32de33dfed4f996e2cfc787cc685f349 65 SMART SM00530 4 59 5.7E-22 T 31-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TK1339 32de33dfed4f996e2cfc787cc685f349 65 SUPERFAMILY SSF47413 2 64 4.29E-22 T 31-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TK1339 32de33dfed4f996e2cfc787cc685f349 65 Pfam PF01381 Helix-turn-helix 5 58 3.9E-21 T 31-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TK1339 32de33dfed4f996e2cfc787cc685f349 65 Gene3D G3DSA:1.10.260.40 1 65 1.3E-32 T 31-10-2018 TK0210 93a2432d4e417dd30dcb769c1e4712a1 235 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 3 223 2.8E-75 T 31-10-2018 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 TK0210 93a2432d4e417dd30dcb769c1e4712a1 235 ProSitePatterns PS01057 SAICAR synthetase signature 1. 81 95 - T 31-10-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TK0210 93a2432d4e417dd30dcb769c1e4712a1 235 SUPERFAMILY SSF56104 3 230 1.7E-81 T 31-10-2018 TK0210 93a2432d4e417dd30dcb769c1e4712a1 235 Gene3D G3DSA:3.30.200.20 17 227 2.0E-96 T 31-10-2018 TK0210 93a2432d4e417dd30dcb769c1e4712a1 235 Gene3D G3DSA:3.30.470.20 80 215 2.0E-96 T 31-10-2018 TK0210 93a2432d4e417dd30dcb769c1e4712a1 235 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 1 229 31.581 T 31-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TK0210 93a2432d4e417dd30dcb769c1e4712a1 235 ProSitePatterns PS01058 SAICAR synthetase signature 2. 167 175 - T 31-10-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TK0210 93a2432d4e417dd30dcb769c1e4712a1 235 Pfam PF01259 SAICAR synthetase 3 223 2.8E-67 T 31-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TK2168 c86191b19da7362c9fd836be4a301f24 643 SUPERFAMILY SSF54211 48 233 1.93E-25 T 31-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TK2168 c86191b19da7362c9fd836be4a301f24 643 TIGRFAM TIGR04288 CGP_CTERM: CGP-CTERM domain 624 642 1.4E-6 T 31-10-2018 IPR027552 CGP-CTERM domain TK2168 c86191b19da7362c9fd836be4a301f24 643 Gene3D G3DSA:3.30.230.10 32 234 5.5E-28 T 31-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TK2168 c86191b19da7362c9fd836be4a301f24 643 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 77 181 2.2E-12 T 31-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 TK0714 26df072aa7a44d88082753ac14461e6d 672 Pfam PF07670 Nucleoside recognition 348 442 7.1E-14 T 31-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 TK0714 26df072aa7a44d88082753ac14461e6d 672 Pfam PF07670 Nucleoside recognition 509 643 2.2E-33 T 31-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 TK0714 26df072aa7a44d88082753ac14461e6d 672 SUPERFAMILY SSF52540 6 187 1.05E-44 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK0714 26df072aa7a44d88082753ac14461e6d 672 Pfam PF02421 Ferrous iron transport protein B 5 159 2.0E-70 T 31-10-2018 IPR030389 FeoB-type guanine nucleotide-binding (G) domain GO:0005525 TK0714 26df072aa7a44d88082753ac14461e6d 672 TIGRFAM TIGR00437 feoB: ferrous iron transport protein B 10 640 6.4E-220 T 31-10-2018 IPR003373 Ferrous iron transport protein B GO:0005525|GO:0015093|GO:0015684|GO:0016021 TK0714 26df072aa7a44d88082753ac14461e6d 672 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 6 26 6.6E-6 T 31-10-2018 IPR006073 GTP binding domain GO:0005525 TK0714 26df072aa7a44d88082753ac14461e6d 672 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 27 45 6.6E-6 T 31-10-2018 IPR006073 GTP binding domain GO:0005525 TK0714 26df072aa7a44d88082753ac14461e6d 672 Pfam PF07664 Ferrous iron transport protein B C terminus 453 504 4.8E-20 T 31-10-2018 IPR011640 Ferrous iron transport protein B, C-terminal GO:0015093|GO:0015684|GO:0016021 TK0714 26df072aa7a44d88082753ac14461e6d 672 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 1 155 2.1E-12 T 31-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 TK0714 26df072aa7a44d88082753ac14461e6d 672 Gene3D G3DSA:3.40.50.300 5 183 7.9E-50 T 31-10-2018 TK1111 c6ae8ef038afa341112792a19bb10a33 189 Hamap MF_01410 Glucose-6-phosphate isomerase [pgiA]. 2 185 46.144 T 31-10-2018 IPR016758 Glucose-6-phosphate isomerase, archaea/bacteria GO:0004347|GO:0005506 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385 TK1111 c6ae8ef038afa341112792a19bb10a33 189 SUPERFAMILY SSF51182 2 188 1.26E-43 T 31-10-2018 IPR011051 RmlC-like cupin domain superfamily TK1111 c6ae8ef038afa341112792a19bb10a33 189 Gene3D G3DSA:2.60.120.10 1 189 5.3E-75 T 31-10-2018 IPR014710 RmlC-like jelly roll fold TK1111 c6ae8ef038afa341112792a19bb10a33 189 Pfam PF06560 Glucose-6-phosphate isomerase (GPI) 25 182 4.8E-41 T 31-10-2018 IPR010551 Glucose-6-phosphate isomerase, prokaryote GO:0004347|GO:0005737|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385 TK1111 c6ae8ef038afa341112792a19bb10a33 189 PIRSF PIRSF019325 1 189 9.0E-75 T 31-10-2018 IPR016758 Glucose-6-phosphate isomerase, archaea/bacteria GO:0004347|GO:0005506 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385 TK2110 387d93be35650ee5488a08759214f71c 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 32 51 9.2E-14 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TK2110 387d93be35650ee5488a08759214f71c 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 5 21 9.2E-14 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TK2110 387d93be35650ee5488a08759214f71c 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 21 32 9.2E-14 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TK2110 387d93be35650ee5488a08759214f71c 150 SUPERFAMILY SSF54909 65 147 4.83E-17 T 31-10-2018 IPR011008 Dimeric alpha-beta barrel TK2110 387d93be35650ee5488a08759214f71c 150 SUPERFAMILY SSF46785 5 63 7.61E-12 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TK2110 387d93be35650ee5488a08759214f71c 150 Pfam PF01037 Lrp/AsnC ligand binding domain 79 142 8.1E-15 T 31-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain TK2110 387d93be35650ee5488a08759214f71c 150 Gene3D G3DSA:3.30.70.920 59 150 2.7E-22 T 31-10-2018 TK2110 387d93be35650ee5488a08759214f71c 150 Gene3D G3DSA:1.10.10.10 2 56 2.9E-19 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TK2110 387d93be35650ee5488a08759214f71c 150 Pfam PF13412 Winged helix-turn-helix DNA-binding 5 52 3.2E-15 T 31-10-2018 TK2110 387d93be35650ee5488a08759214f71c 150 SMART SM00344 5 114 5.0E-45 T 31-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 TK2303 d46817327cb463c1d43f828d856fe672 546 SUPERFAMILY SSF54849 146 404 1.19E-29 T 31-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily TK2303 d46817327cb463c1d43f828d856fe672 546 Pfam PF00118 TCP-1/cpn60 chaperonin family 35 525 1.9E-184 T 31-10-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 TK2303 d46817327cb463c1d43f828d856fe672 546 Gene3D G3DSA:3.50.7.10 218 369 4.7E-214 T 31-10-2018 IPR027409 GroEL-like apical domain superfamily TK2303 d46817327cb463c1d43f828d856fe672 546 ProSitePatterns PS00750 Chaperonins TCP-1 signature 1. 40 52 - T 31-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 TK2303 d46817327cb463c1d43f828d856fe672 546 SUPERFAMILY SSF48592 17 524 3.43E-93 T 31-10-2018 IPR027413 GroEL-like equatorial domain superfamily TK2303 d46817327cb463c1d43f828d856fe672 546 TIGRFAM TIGR02339 thermosome_arch: thermosome, various subunits, archaeal 8 524 9.4E-245 T 31-10-2018 IPR012714 Thermosome, archaeal GO:0005524|GO:0006457|GO:0051082 TK2303 d46817327cb463c1d43f828d856fe672 546 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 89 108 8.3E-35 T 31-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 TK2303 d46817327cb463c1d43f828d856fe672 546 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 373 395 8.3E-35 T 31-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 TK2303 d46817327cb463c1d43f828d856fe672 546 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 407 419 8.3E-35 T 31-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 TK2303 d46817327cb463c1d43f828d856fe672 546 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 37 53 8.3E-35 T 31-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 TK2303 d46817327cb463c1d43f828d856fe672 546 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 59 77 8.3E-35 T 31-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 TK2303 d46817327cb463c1d43f828d856fe672 546 SUPERFAMILY SSF52029 212 378 1.88E-63 T 31-10-2018 IPR027409 GroEL-like apical domain superfamily TK2303 d46817327cb463c1d43f828d856fe672 546 Gene3D G3DSA:3.30.260.10 147 405 4.7E-214 T 31-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily TK2303 d46817327cb463c1d43f828d856fe672 546 ProSitePatterns PS00751 Chaperonins TCP-1 signature 2. 61 77 - T 31-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 TK2303 d46817327cb463c1d43f828d856fe672 546 ProSitePatterns PS00995 Chaperonins TCP-1 signature 3. 89 97 - T 31-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 TK2303 d46817327cb463c1d43f828d856fe672 546 Gene3D G3DSA:1.10.560.10 28 522 4.7E-214 T 31-10-2018 IPR027413 GroEL-like equatorial domain superfamily TK1691 c0ab77f7eed06d8134458aab7b6f3249 351 SUPERFAMILY SSF53335 164 285 3.09E-8 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TK1691 c0ab77f7eed06d8134458aab7b6f3249 351 Gene3D G3DSA:1.10.10.10 1 83 6.2E-33 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TK1691 c0ab77f7eed06d8134458aab7b6f3249 351 Pfam PF01861 Protein of unknown function DUF43 106 350 2.7E-120 T 31-10-2018 IPR002723 N(4)-bis(aminopropyl)spermidine synthase, C-terminal TK1691 c0ab77f7eed06d8134458aab7b6f3249 351 Gene3D G3DSA:3.40.50.150 101 326 8.1E-86 T 31-10-2018 TK1691 c0ab77f7eed06d8134458aab7b6f3249 351 PIRSF PIRSF005895 1 351 4.8E-159 T 31-10-2018 IPR014435 N(4)-bis(aminopropyl)spermidine synthase GO:0006596|GO:0016765 TK1691 c0ab77f7eed06d8134458aab7b6f3249 351 Hamap MF_01947 N(4)-bis(aminopropyl)spermidine synthase [bpsA]. 15 351 50.735 T 31-10-2018 IPR014435 N(4)-bis(aminopropyl)spermidine synthase GO:0006596|GO:0016765 TK0871 f895ecb2f5a58455c0c2d23ddff715c3 315 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 8 148 6.5E-51 T 31-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 TK0871 f895ecb2f5a58455c0c2d23ddff715c3 315 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 53 60 - T 31-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TK0871 f895ecb2f5a58455c0c2d23ddff715c3 315 PRINTS PR00102 Ornithine carbamoyltransferase signature 124 138 1.8E-30 T 31-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 TK0871 f895ecb2f5a58455c0c2d23ddff715c3 315 PRINTS PR00102 Ornithine carbamoyltransferase signature 84 97 1.8E-30 T 31-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 TK0871 f895ecb2f5a58455c0c2d23ddff715c3 315 PRINTS PR00102 Ornithine carbamoyltransferase signature 227 237 1.8E-30 T 31-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 TK0871 f895ecb2f5a58455c0c2d23ddff715c3 315 PRINTS PR00102 Ornithine carbamoyltransferase signature 289 300 1.8E-30 T 31-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 TK0871 f895ecb2f5a58455c0c2d23ddff715c3 315 PRINTS PR00102 Ornithine carbamoyltransferase signature 51 65 1.8E-30 T 31-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 TK0871 f895ecb2f5a58455c0c2d23ddff715c3 315 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 154 308 1.0E-66 T 31-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 TK0871 f895ecb2f5a58455c0c2d23ddff715c3 315 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 7 311 85.794 T 31-10-2018 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 TK0871 f895ecb2f5a58455c0c2d23ddff715c3 315 SUPERFAMILY SSF53671 4 313 3.93E-117 T 31-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 TK0871 f895ecb2f5a58455c0c2d23ddff715c3 315 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 8 310 6.6E-146 T 31-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 TK0871 f895ecb2f5a58455c0c2d23ddff715c3 315 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 275 298 7.7E-30 T 31-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TK0871 f895ecb2f5a58455c0c2d23ddff715c3 315 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 135 146 7.7E-30 T 31-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TK0871 f895ecb2f5a58455c0c2d23ddff715c3 315 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 53 72 7.7E-30 T 31-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TK0871 f895ecb2f5a58455c0c2d23ddff715c3 315 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 263 272 7.7E-30 T 31-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TK0871 f895ecb2f5a58455c0c2d23ddff715c3 315 Gene3D G3DSA:3.40.50.1370 10 307 1.8E-139 T 31-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 TK0871 f895ecb2f5a58455c0c2d23ddff715c3 315 Gene3D G3DSA:3.40.50.1370 138 297 1.8E-139 T 31-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 TK1601 fa4797945202b226ae060f80e26a1549 102 Hamap MF_00312 V-type ATP synthase subunit F [atpF]. 1 101 19.868 T 31-10-2018 IPR022944 ATPase, V1 complex, subunit F, bacterial/archaeal TK1601 fa4797945202b226ae060f80e26a1549 102 Gene3D G3DSA:3.40.50.10580 1 102 4.4E-35 T 31-10-2018 IPR036906 ATPase, V1 complex, subunit F superfamily GO:0034220 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TK1601 fa4797945202b226ae060f80e26a1549 102 Pfam PF01990 ATP synthase (F/14-kDa) subunit 3 89 6.9E-19 T 31-10-2018 IPR008218 ATPase, V1 complex, subunit F GO:0034220 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TK1601 fa4797945202b226ae060f80e26a1549 102 SUPERFAMILY SSF159468 3 100 1.05E-19 T 31-10-2018 IPR036906 ATPase, V1 complex, subunit F superfamily GO:0034220 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TK0883 ffa6cf3a99d7e5181fcdaa14d829344a 164 Gene3D G3DSA:3.10.580.10 80 156 7.9E-10 T 31-10-2018 TK0883 ffa6cf3a99d7e5181fcdaa14d829344a 164 PIRSF PIRSF019454 1 163 3.4E-84 T 31-10-2018 IPR016761 Uncharacterised conserved protein UCP019454, CBS TK0883 ffa6cf3a99d7e5181fcdaa14d829344a 164 Pfam PF00571 CBS domain 26 72 2.6E-5 T 31-10-2018 IPR000644 CBS domain TK0883 ffa6cf3a99d7e5181fcdaa14d829344a 164 Pfam PF00571 CBS domain 99 150 1.0E-5 T 31-10-2018 IPR000644 CBS domain TK0883 ffa6cf3a99d7e5181fcdaa14d829344a 164 SUPERFAMILY SSF54631 6 152 1.48E-20 T 31-10-2018 TK0883 ffa6cf3a99d7e5181fcdaa14d829344a 164 Gene3D G3DSA:3.10.580.10 1 75 2.6E-7 T 31-10-2018 TK0883 ffa6cf3a99d7e5181fcdaa14d829344a 164 SMART SM00116 105 152 0.38 T 31-10-2018 IPR000644 CBS domain TK0883 ffa6cf3a99d7e5181fcdaa14d829344a 164 SMART SM00116 24 72 2.5 T 31-10-2018 IPR000644 CBS domain TK0286 d71b37538767de3d82e0acf9e8f85cbc 330 SUPERFAMILY SSF52540 9 167 4.51E-18 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK0286 d71b37538767de3d82e0acf9e8f85cbc 330 Pfam PF03008 Archaea bacterial proteins of unknown function 235 321 2.3E-30 T 31-10-2018 IPR004256 Domain of unknown function DUF234, DEXX-box ATPase C-terminal TK0286 d71b37538767de3d82e0acf9e8f85cbc 330 Gene3D G3DSA:3.40.50.300 6 94 4.6E-13 T 31-10-2018 TK0286 d71b37538767de3d82e0acf9e8f85cbc 330 SUPERFAMILY SSF46785 168 243 1.42E-6 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TK2120 b6cae1fce22ab41a0d40cd5a7ee5b05c 307 SUPERFAMILY SSF117070 164 259 2.35E-14 T 31-10-2018 TK2120 b6cae1fce22ab41a0d40cd5a7ee5b05c 307 Pfam PF03168 Late embryogenesis abundant protein 191 281 1.1E-13 T 31-10-2018 IPR004864 Late embryogenesis abundant protein, LEA_2 subgroup TK2120 b6cae1fce22ab41a0d40cd5a7ee5b05c 307 SMART SM00769 169 284 7.5E-11 T 31-10-2018 IPR013990 Water stress and hypersensitive response domain GO:0009269 TK2120 b6cae1fce22ab41a0d40cd5a7ee5b05c 307 Gene3D G3DSA:2.60.40.10 35 154 1.5E-7 T 31-10-2018 IPR013783 Immunoglobulin-like fold TK2120 b6cae1fce22ab41a0d40cd5a7ee5b05c 307 Gene3D G3DSA:2.60.40.10 168 299 1.7E-29 T 31-10-2018 IPR013783 Immunoglobulin-like fold TK1741 51ca9c21cba3ccc269305739a2e9285e 456 Hamap MF_01264 CCA-adding enzyme [cca]. 1 456 165.706 T 31-10-2018 IPR008229 tRNA nucleotidyltransferase, archaea GO:0001680|GO:0003723|GO:0004810 TK1741 51ca9c21cba3ccc269305739a2e9285e 456 PIRSF PIRSF005335 1 456 2.5E-152 T 31-10-2018 IPR008229 tRNA nucleotidyltransferase, archaea GO:0001680|GO:0003723|GO:0004810 TK1741 51ca9c21cba3ccc269305739a2e9285e 456 Gene3D G3DSA:3.30.70.590 290 431 1.3E-25 T 31-10-2018 TK1741 51ca9c21cba3ccc269305739a2e9285e 456 SUPERFAMILY SSF81301 1 150 2.21E-36 T 31-10-2018 TK1741 51ca9c21cba3ccc269305739a2e9285e 456 SUPERFAMILY SSF55003 265 451 5.89E-43 T 31-10-2018 IPR011068 Nucleotidyltransferase, class I-like, C-terminal GO:0003723|GO:0016779|GO:0031123 TK1741 51ca9c21cba3ccc269305739a2e9285e 456 Gene3D G3DSA:3.30.70.1550 361 400 1.3E-25 T 31-10-2018 TK1741 51ca9c21cba3ccc269305739a2e9285e 456 Pfam PF09249 tRNA nucleotidyltransferase, second domain 155 278 1.2E-39 T 31-10-2018 IPR015329 tRNA nucleotidyltransferase, substrate binding GO:0004810|GO:0016437 TK1741 51ca9c21cba3ccc269305739a2e9285e 456 TIGRFAM TIGR03671 cca_archaeal: CCA-adding enzyme 7 420 1.4E-143 T 31-10-2018 IPR008229 tRNA nucleotidyltransferase, archaea GO:0001680|GO:0003723|GO:0004810 TK1741 51ca9c21cba3ccc269305739a2e9285e 456 Gene3D G3DSA:1.10.1410.30 9 278 5.8E-87 T 31-10-2018 TK1741 51ca9c21cba3ccc269305739a2e9285e 456 Gene3D G3DSA:3.30.460.10 16 152 5.8E-87 T 31-10-2018 TK1741 51ca9c21cba3ccc269305739a2e9285e 456 SUPERFAMILY SSF81631 153 279 3.66E-37 T 31-10-2018 TK1741 51ca9c21cba3ccc269305739a2e9285e 456 Pfam PF01909 Nucleotidyltransferase domain 36 141 9.8E-12 T 31-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 TK1721 5c196f4ee91b83781a9b087e287d3239 359 Pfam PF13439 Glycosyltransferase Family 4 16 177 5.9E-15 T 31-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 TK1721 5c196f4ee91b83781a9b087e287d3239 359 Gene3D G3DSA:3.40.50.2000 17 351 6.4E-59 T 31-10-2018 TK1721 5c196f4ee91b83781a9b087e287d3239 359 Gene3D G3DSA:3.40.50.2000 175 340 6.4E-59 T 31-10-2018 TK1721 5c196f4ee91b83781a9b087e287d3239 359 Pfam PF00534 Glycosyl transferases group 1 180 336 1.4E-33 T 31-10-2018 IPR001296 Glycosyl transferase, family 1 TK1721 5c196f4ee91b83781a9b087e287d3239 359 SUPERFAMILY SSF53756 12 355 4.19E-71 T 31-10-2018 TK0965 a6d71fc0d77a6dd225aeaa2ad0bbb494 86 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 12 81 4.7E-10 T 31-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family TK0965 a6d71fc0d77a6dd225aeaa2ad0bbb494 86 Gene3D G3DSA:3.30.2310.20 1 84 2.0E-21 T 31-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily TK0965 a6d71fc0d77a6dd225aeaa2ad0bbb494 86 SUPERFAMILY SSF143011 1 81 1.03E-23 T 31-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily TK1708 62451b1383c1bd719cd35ba6b6ea7baa 316 Gene3D G3DSA:3.90.25.10 229 316 4.2E-24 T 31-10-2018 TK1708 62451b1383c1bd719cd35ba6b6ea7baa 316 Gene3D G3DSA:3.40.50.720 1 180 4.5E-53 T 31-10-2018 TK1708 62451b1383c1bd719cd35ba6b6ea7baa 316 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 241 8.2E-58 T 31-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 TK1708 62451b1383c1bd719cd35ba6b6ea7baa 316 SUPERFAMILY SSF51735 1 315 2.07E-87 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily TK1708 62451b1383c1bd719cd35ba6b6ea7baa 316 Gene3D G3DSA:3.90.25.10 181 228 1.2E-12 T 31-10-2018 TK0156 1806942c5c2fb3c538a61887b8f81d98 742 Pfam PF02743 Cache domain 45 285 2.6E-38 T 31-10-2018 IPR033479 Double Cache domain 1 TK0156 1806942c5c2fb3c538a61887b8f81d98 742 Gene3D G3DSA:1.10.287.950 438 741 7.4E-62 T 31-10-2018 TK0156 1806942c5c2fb3c538a61887b8f81d98 742 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 530 670 1.1E-34 T 31-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TK0156 1806942c5c2fb3c538a61887b8f81d98 742 SUPERFAMILY SSF103190 106 202 6.08E-10 T 31-10-2018 IPR029151 Periplasmic sensor-like domain superfamily TK0156 1806942c5c2fb3c538a61887b8f81d98 742 SMART SM00283 466 734 2.1E-53 T 31-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TK0156 1806942c5c2fb3c538a61887b8f81d98 742 Gene3D G3DSA:1.20.1480.50 298 399 6.8E-7 T 31-10-2018 TK0156 1806942c5c2fb3c538a61887b8f81d98 742 Gene3D G3DSA:3.30.450.20 84 295 2.6E-35 T 31-10-2018 TK0156 1806942c5c2fb3c538a61887b8f81d98 742 Gene3D G3DSA:3.30.450.20 87 195 2.6E-35 T 31-10-2018 TK0156 1806942c5c2fb3c538a61887b8f81d98 742 SUPERFAMILY SSF58104 369 740 1.15E-57 T 31-10-2018 TK1640 79939a77049691e91ce33a228565231b 106 SUPERFAMILY SSF101386 1 104 1.6E-32 T 31-10-2018 TK1640 79939a77049691e91ce33a228565231b 106 Pfam PF12643 MazG-like family 30 103 2.6E-21 T 31-10-2018 IPR025984 dCTP pyrophosphatase 1 GO:0009143|GO:0047429 KEGG: 00240+3.6.1.12|Reactome: R-HSA-499943 TK1640 79939a77049691e91ce33a228565231b 106 Gene3D G3DSA:1.10.287.1080 1 104 3.5E-34 T 31-10-2018 TK1640 79939a77049691e91ce33a228565231b 106 PIRSF PIRSF029826 1 106 1.8E-41 T 31-10-2018 IPR025984 dCTP pyrophosphatase 1 GO:0009143|GO:0047429 KEGG: 00240+3.6.1.12|Reactome: R-HSA-499943 TK0381 cc79437da9f235d4126cb90c7d624ae1 287 Pfam PF16795 Archaeal phage integrase 118 278 1.2E-60 T 31-10-2018 IPR031857 Integrase SSV1, C-terminal TK0381 cc79437da9f235d4126cb90c7d624ae1 287 Gene3D G3DSA:1.10.443.10 115 282 3.6E-39 T 31-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 TK0381 cc79437da9f235d4126cb90c7d624ae1 287 SUPERFAMILY SSF56349 33 263 2.28E-12 T 31-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 TK2104 5d64deb616b466839632eb647bd819f2 224 PIRSF PIRSF001357 1 223 4.4E-91 T 31-10-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 TK2104 5d64deb616b466839632eb647bd819f2 224 Pfam PF01791 DeoC/LacD family aldolase 9 217 5.8E-24 T 31-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 TK2104 5d64deb616b466839632eb647bd819f2 224 Hamap MF_00114 Deoxyribose-phosphate aldolase [deoC]. 4 222 39.014 T 31-10-2018 IPR028581 Deoxyribose-phosphate aldolase type I GO:0004139 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180 TK2104 5d64deb616b466839632eb647bd819f2 224 SUPERFAMILY SSF51569 3 220 6.07E-93 T 31-10-2018 TK2104 5d64deb616b466839632eb647bd819f2 224 TIGRFAM TIGR00126 deoC: deoxyribose-phosphate aldolase 6 218 3.1E-90 T 31-10-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 TK2104 5d64deb616b466839632eb647bd819f2 224 SMART SM01133 5 220 1.7E-116 T 31-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 TK2104 5d64deb616b466839632eb647bd819f2 224 Gene3D G3DSA:3.20.20.70 1 223 1.2E-106 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TK1731 329a68ed7c43815bb2b10150d02059c2 353 SUPERFAMILY SSF53756 2 351 3.62E-70 T 31-10-2018 TK1731 329a68ed7c43815bb2b10150d02059c2 353 Gene3D G3DSA:3.40.50.2000 1 180 6.4E-26 T 31-10-2018 TK1731 329a68ed7c43815bb2b10150d02059c2 353 Gene3D G3DSA:3.40.50.2000 181 351 6.5E-43 T 31-10-2018 TK1731 329a68ed7c43815bb2b10150d02059c2 353 Pfam PF13439 Glycosyltransferase Family 4 15 168 2.4E-18 T 31-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 TK1731 329a68ed7c43815bb2b10150d02059c2 353 Pfam PF00534 Glycosyl transferases group 1 192 346 4.8E-38 T 31-10-2018 IPR001296 Glycosyl transferase, family 1 TK2101 cd156adfb130990e550aa3c00c531363 445 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 260 297 - T 31-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TK2101 cd156adfb130990e550aa3c00c531363 445 SUPERFAMILY SSF53383 34 441 3.24E-128 T 31-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TK2101 cd156adfb130990e550aa3c00c531363 445 Pfam PF00202 Aminotransferase class-III 34 440 1.6E-117 T 31-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TK2101 cd156adfb130990e550aa3c00c531363 445 Gene3D G3DSA:3.90.1150.10 14 438 7.2E-153 T 31-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TK2101 cd156adfb130990e550aa3c00c531363 445 Gene3D G3DSA:3.40.640.10 72 340 7.2E-153 T 31-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TK2101 cd156adfb130990e550aa3c00c531363 445 PIRSF PIRSF000521 2 443 1.3E-60 T 31-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TK0772 80b35df4f835bedb131ede04e1fbaab2 727 SUPERFAMILY SSF82866 551 713 1.96E-21 T 31-10-2018 TK0772 80b35df4f835bedb131ede04e1fbaab2 727 Pfam PF03176 MMPL family 417 716 4.0E-32 T 31-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 TK0772 80b35df4f835bedb131ede04e1fbaab2 727 Pfam PF03176 MMPL family 129 341 6.0E-36 T 31-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 TK0772 80b35df4f835bedb131ede04e1fbaab2 727 SUPERFAMILY SSF82866 132 332 2.35E-24 T 31-10-2018 TK0772 80b35df4f835bedb131ede04e1fbaab2 727 Gene3D G3DSA:1.20.1640.10 174 342 8.2E-9 T 31-10-2018 TK0772 80b35df4f835bedb131ede04e1fbaab2 727 Gene3D G3DSA:1.20.1640.10 343 401 8.2E-9 T 31-10-2018 TK1528 732defa22fde2c8b7889c54e464b6554 183 PIRSF PIRSF002161 2 180 3.2E-56 T 31-10-2018 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1528 732defa22fde2c8b7889c54e464b6554 183 Pfam PF00673 ribosomal L5P family C-terminus 72 171 2.4E-27 T 31-10-2018 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1528 732defa22fde2c8b7889c54e464b6554 183 Pfam PF00281 Ribosomal protein L5 16 68 4.2E-20 T 31-10-2018 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1528 732defa22fde2c8b7889c54e464b6554 183 Hamap MF_01333_A 50S ribosomal protein L5 [rplE]. 14 181 42.022 T 31-10-2018 IPR022804 Ribosomal protein L5, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 TK1528 732defa22fde2c8b7889c54e464b6554 183 SUPERFAMILY SSF55282 15 178 1.3E-57 T 31-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1528 732defa22fde2c8b7889c54e464b6554 183 Gene3D G3DSA:3.30.1440.10 10 181 1.7E-72 T 31-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK2210 9fe857bf59e16683becf5bea5ae25e27 443 PIRSF PIRSF018871 1 443 2.8E-118 T 31-10-2018 IPR016738 DNA double-strand break repair nuclease NurA-like TK2210 9fe857bf59e16683becf5bea5ae25e27 443 Pfam PF09376 NurA domain 44 408 2.7E-76 T 31-10-2018 IPR018977 NurA domain TK2210 9fe857bf59e16683becf5bea5ae25e27 443 SMART SM00933 43 408 5.1E-38 T 31-10-2018 IPR018977 NurA domain TK0888 4f6f32baf8131414994856c85dbd8660 80 Gene3D G3DSA:2.10.260.10 1 43 6.4E-15 T 31-10-2018 TK0888 4f6f32baf8131414994856c85dbd8660 80 SMART SM00966 4 49 5.7E-13 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 TK0888 4f6f32baf8131414994856c85dbd8660 80 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 4 42 3.0E-16 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 TK0888 4f6f32baf8131414994856c85dbd8660 80 SUPERFAMILY SSF89447 1 45 3.92E-14 T 31-10-2018 IPR037914 SpoVT-AbrB domain superfamily TK0888 4f6f32baf8131414994856c85dbd8660 80 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 4 44 1.1E-10 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 TK1418 7427c3141459e046ee7269aefb74c5e0 165 SUPERFAMILY SSF54747 3 82 6.15E-26 T 31-10-2018 IPR036796 Ribosomal protein L11/L12, N-terminal domain superfamily TK1418 7427c3141459e046ee7269aefb74c5e0 165 SMART SM00649 5 138 9.9E-63 T 31-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 TK1418 7427c3141459e046ee7269aefb74c5e0 165 Gene3D G3DSA:2.10.260.30 1 69 3.4E-28 T 31-10-2018 TK1418 7427c3141459e046ee7269aefb74c5e0 165 SUPERFAMILY SSF46906 71 142 1.7E-22 T 31-10-2018 IPR036769 Ribosomal protein L11, C-terminal domain superfamily TK1418 7427c3141459e046ee7269aefb74c5e0 165 Gene3D G3DSA:1.10.10.250 73 164 4.0E-35 T 31-10-2018 IPR036769 Ribosomal protein L11, C-terminal domain superfamily TK1418 7427c3141459e046ee7269aefb74c5e0 165 Pfam PF00298 Ribosomal protein L11, RNA binding domain 71 137 9.8E-22 T 31-10-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 TK1418 7427c3141459e046ee7269aefb74c5e0 165 Pfam PF03946 Ribosomal protein L11, N-terminal domain 5 58 1.3E-22 T 31-10-2018 IPR020784 Ribosomal protein L11, N-terminal TK1418 7427c3141459e046ee7269aefb74c5e0 165 ProSitePatterns PS00359 Ribosomal protein L11 signature. 124 139 - T 31-10-2018 IPR020785 Ribosomal protein L11, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1418 7427c3141459e046ee7269aefb74c5e0 165 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 1 139 27.981 T 31-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 TK0819 f0eecab42efb37568357edf086339ef9 338 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 8 167 36.92 T 31-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 TK0819 f0eecab42efb37568357edf086339ef9 338 TIGRFAM TIGR00357 TIGR00357: methionine-R-sulfoxide reductase 198 330 7.3E-50 T 31-10-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 TK0819 f0eecab42efb37568357edf086339ef9 338 Pfam PF01641 SelR domain 203 321 4.1E-38 T 31-10-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 TK0819 f0eecab42efb37568357edf086339ef9 338 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 9 155 3.7E-58 T 31-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 TK0819 f0eecab42efb37568357edf086339ef9 338 SUPERFAMILY SSF55068 8 171 4.45E-72 T 31-10-2018 IPR036509 Peptide methionine sulphoxide reductase MsrA superfamily GO:0008113|GO:0055114 Reactome: R-HSA-5676934 TK0819 f0eecab42efb37568357edf086339ef9 338 SUPERFAMILY SSF51316 197 337 4.6E-50 T 31-10-2018 IPR011057 Mss4-like superfamily TK0819 f0eecab42efb37568357edf086339ef9 338 Gene3D G3DSA:3.30.1060.10 3 168 4.4E-66 T 31-10-2018 IPR036509 Peptide methionine sulphoxide reductase MsrA superfamily GO:0008113|GO:0055114 Reactome: R-HSA-5676934 TK0819 f0eecab42efb37568357edf086339ef9 338 Pfam PF01625 Peptide methionine sulfoxide reductase 10 161 1.8E-60 T 31-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 TK0819 f0eecab42efb37568357edf086339ef9 338 Gene3D G3DSA:2.170.150.20 193 338 3.1E-47 T 31-10-2018 TK0182 e9f2df9a98a48782ebc16471d292e563 222 TIGRFAM TIGR00266 TIGR00266: TIGR00266 family protein 1 220 7.8E-86 T 31-10-2018 IPR002838 Mitochondrial biogenesis protein AIM24 TK0182 e9f2df9a98a48782ebc16471d292e563 222 Pfam PF01987 Mitochondrial biogenesis AIM24 3 205 3.7E-62 T 31-10-2018 IPR002838 Mitochondrial biogenesis protein AIM24 TK0182 e9f2df9a98a48782ebc16471d292e563 222 Gene3D G3DSA:3.60.160.10 1 222 2.1E-81 T 31-10-2018 IPR036983 Mitochondrial biogenesis AIM24 superfamily TK0182 e9f2df9a98a48782ebc16471d292e563 222 SUPERFAMILY SSF51219 1 221 4.45E-73 T 31-10-2018 IPR016031 Tryptophan RNA-binding attenuator protein-like domain superfamily TK1533 a7533e6f2e4aab8ea1150560b7ffe39f 125 Pfam PF01868 Domain of unknown function UPF0086 42 121 2.8E-19 T 31-10-2018 IPR002730 Ribonuclease P/MRP, subunit p29 GO:0003723|GO:0004540|GO:0006396|GO:0030677 Reactome: R-HSA-6784531 TK1533 a7533e6f2e4aab8ea1150560b7ffe39f 125 SMART SM00538 37 125 5.2E-33 T 31-10-2018 IPR002730 Ribonuclease P/MRP, subunit p29 GO:0003723|GO:0004540|GO:0006396|GO:0030677 Reactome: R-HSA-6784531 TK1533 a7533e6f2e4aab8ea1150560b7ffe39f 125 Gene3D G3DSA:2.30.30.210 17 125 1.0E-40 T 31-10-2018 IPR036980 Ribonuclease P/MRP, subunit p29 superfamily GO:0003723|GO:0004540|GO:0008033|GO:0030677 Reactome: R-HSA-6784531 TK1533 a7533e6f2e4aab8ea1150560b7ffe39f 125 Hamap MF_00754 Ribonuclease P protein component 1 [rnp1]. 45 120 19.388 T 31-10-2018 IPR023538 Ribonuclease P protein component 1 GO:0001682|GO:0004526 TK1533 a7533e6f2e4aab8ea1150560b7ffe39f 125 SUPERFAMILY SSF101744 38 124 1.2E-24 T 31-10-2018 IPR023534 Rof/RNase P-like Reactome: R-HSA-6784531 TK1814 cd2ca75d39f2af589bb8d3df674e4442 384 Gene3D G3DSA:3.90.1150.10 6 374 4.8E-129 T 31-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TK1814 cd2ca75d39f2af589bb8d3df674e4442 384 Gene3D G3DSA:3.40.640.10 40 290 4.8E-129 T 31-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TK1814 cd2ca75d39f2af589bb8d3df674e4442 384 SUPERFAMILY SSF53383 2 384 6.52E-110 T 31-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TK1814 cd2ca75d39f2af589bb8d3df674e4442 384 ProSitePatterns PS00392 DDC / GAD / HDC / TyrDC pyridoxal-phosphate attachment site. 224 245 - T 31-10-2018 IPR021115 Pyridoxal-phosphate binding site GO:0016831 TK1814 cd2ca75d39f2af589bb8d3df674e4442 384 Hamap MF_01610 Probable L-tyrosine/L-aspartate decarboxylase [mfnA]. 14 381 51.246 T 31-10-2018 IPR020931 Decarboxylase MfnA, archaea GO:0016831 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 TK1814 cd2ca75d39f2af589bb8d3df674e4442 384 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 66 331 1.1E-36 T 31-10-2018 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 TK1814 cd2ca75d39f2af589bb8d3df674e4442 384 TIGRFAM TIGR03812 tyr_de_CO2_Arch: tyrosine decarboxylase MnfA 8 380 4.0E-173 T 31-10-2018 IPR020931 Decarboxylase MfnA, archaea GO:0016831 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 TK1334 0d5bfbb41ca3dc84637cdb1abe80245c 185 SUPERFAMILY SSF52540 1 183 1.78E-19 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK1334 0d5bfbb41ca3dc84637cdb1abe80245c 185 Pfam PF13207 AAA domain 6 136 1.4E-19 T 31-10-2018 TK1334 0d5bfbb41ca3dc84637cdb1abe80245c 185 Gene3D G3DSA:3.40.50.300 2 183 3.7E-45 T 31-10-2018 TK1334 0d5bfbb41ca3dc84637cdb1abe80245c 185 Hamap MF_01111 UPF0200 protein . 2 182 31.527 T 31-10-2018 IPR022970 Nucleoside triphosphate hydrolase-related TK0028 32e626860c9f5ab92db3815b5f64d1be 421 SMART SM00997 188 349 3.5E-111 T 31-10-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 TK0028 32e626860c9f5ab92db3815b5f64d1be 421 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 141 416 1.0E-28 T 31-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 TK0028 32e626860c9f5ab92db3815b5f64d1be 421 Gene3D G3DSA:3.40.50.720 190 349 8.2E-179 T 31-10-2018 TK0028 32e626860c9f5ab92db3815b5f64d1be 421 SMART SM00996 6 420 4.9E-143 T 31-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 TK0028 32e626860c9f5ab92db3815b5f64d1be 421 ProSitePatterns PS00739 S-adenosyl-L-homocysteine hydrolase signature 2. 210 226 - T 31-10-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 TK0028 32e626860c9f5ab92db3815b5f64d1be 421 Gene3D G3DSA:3.40.50.1480 9 410 8.2E-179 T 31-10-2018 TK0028 32e626860c9f5ab92db3815b5f64d1be 421 Pfam PF00670 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 188 348 1.5E-50 T 31-10-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 TK0028 32e626860c9f5ab92db3815b5f64d1be 421 SUPERFAMILY SSF51735 188 350 1.18E-68 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily TK0028 32e626860c9f5ab92db3815b5f64d1be 421 TIGRFAM TIGR00936 ahcY: adenosylhomocysteinase 7 421 3.0E-211 T 31-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 TK0028 32e626860c9f5ab92db3815b5f64d1be 421 Hamap MF_00563 Adenosylhomocysteinase [ahcY]. 2 421 50.595 T 31-10-2018 IPR034373 Adenosylhomocysteinase GO:0004013|GO:0019510|GO:0051287 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-2408508|Reactome: R-HSA-5578997 TK0028 32e626860c9f5ab92db3815b5f64d1be 421 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 6 139 1.4E-35 T 31-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 TK0028 32e626860c9f5ab92db3815b5f64d1be 421 ProSitePatterns PS00738 S-adenosyl-L-homocysteine hydrolase signature 1. 78 92 - T 31-10-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 TK0028 32e626860c9f5ab92db3815b5f64d1be 421 PIRSF PIRSF001109 1 421 1.3E-197 T 31-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 TK0028 32e626860c9f5ab92db3815b5f64d1be 421 SUPERFAMILY SSF52283 5 421 4.31E-103 T 31-10-2018 TK1139 87b5ebbf78a0c4214fa632652c08d5ab 368 ProSitePatterns PS00674 AAA-protein family signature. 228 247 - T 31-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 TK1139 87b5ebbf78a0c4214fa632652c08d5ab 368 Gene3D G3DSA:1.10.8.60 257 346 1.7E-76 T 31-10-2018 TK1139 87b5ebbf78a0c4214fa632652c08d5ab 368 Gene3D G3DSA:3.40.50.300 87 362 1.7E-76 T 31-10-2018 TK1139 87b5ebbf78a0c4214fa632652c08d5ab 368 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 126 255 1.7E-37 T 31-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TK1139 87b5ebbf78a0c4214fa632652c08d5ab 368 Pfam PF09336 Vps4 C terminal oligomerisation domain 326 366 1.2E-4 T 31-10-2018 IPR015415 Vps4 oligomerisation, C-terminal TK1139 87b5ebbf78a0c4214fa632652c08d5ab 368 SUPERFAMILY SSF52540 90 365 1.95E-52 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK1139 87b5ebbf78a0c4214fa632652c08d5ab 368 SMART SM00382 122 258 2.1E-13 T 31-10-2018 IPR003593 AAA+ ATPase domain TK1332 6d45967d130f4f8fbec7b2c42971a8ee 1125 Gene3D G3DSA:3.40.50.300 201 351 3.5E-34 T 31-10-2018 TK1332 6d45967d130f4f8fbec7b2c42971a8ee 1125 Gene3D G3DSA:3.40.50.300 734 802 3.2E-20 T 31-10-2018 TK1332 6d45967d130f4f8fbec7b2c42971a8ee 1125 Pfam PF00270 DEAD/DEAH box helicase 26 180 4.7E-25 T 31-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 TK1332 6d45967d130f4f8fbec7b2c42971a8ee 1125 Gene3D G3DSA:3.40.50.300 8 200 3.1E-74 T 31-10-2018 TK1332 6d45967d130f4f8fbec7b2c42971a8ee 1125 SUPERFAMILY SSF52540 196 333 8.71E-22 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK1332 6d45967d130f4f8fbec7b2c42971a8ee 1125 SUPERFAMILY SSF46785 808 895 2.67E-16 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TK1332 6d45967d130f4f8fbec7b2c42971a8ee 1125 SMART SM00278 1081 1100 3.2 T 31-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 TK1332 6d45967d130f4f8fbec7b2c42971a8ee 1125 SMART SM00278 1048 1067 3.0 T 31-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 TK1332 6d45967d130f4f8fbec7b2c42971a8ee 1125 Pfam PF14890 Intein splicing domain 365 734 1.5E-9 T 31-10-2018 TK1332 6d45967d130f4f8fbec7b2c42971a8ee 1125 SUPERFAMILY SSF51294 332 462 4.58E-18 T 31-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TK1332 6d45967d130f4f8fbec7b2c42971a8ee 1125 Gene3D G3DSA:1.10.3380.30 814 1044 5.1E-73 T 31-10-2018 TK1332 6d45967d130f4f8fbec7b2c42971a8ee 1125 SUPERFAMILY SSF158702 896 1104 1.12E-59 T 31-10-2018 TK1332 6d45967d130f4f8fbec7b2c42971a8ee 1125 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 714 735 0.0029 T 31-10-2018 IPR030934 Intein C-terminal splicing region TK1332 6d45967d130f4f8fbec7b2c42971a8ee 1125 Gene3D G3DSA:1.10.150.20 1046 1102 2.0E-23 T 31-10-2018 TK1332 6d45967d130f4f8fbec7b2c42971a8ee 1125 SMART SM00305 695 740 9.6E-7 T 31-10-2018 IPR003586 Hint domain C-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TK1332 6d45967d130f4f8fbec7b2c42971a8ee 1125 Hamap MF_00442 ATP-dependent DNA helicase Hel308 [hel308]. 9 1103 26.758 T 31-10-2018 IPR022965 ATP-dependent DNA helicase Hel308 GO:0004386 TK1332 6d45967d130f4f8fbec7b2c42971a8ee 1125 Pfam PF14528 LAGLIDADG-like domain 595 678 2.7E-14 T 31-10-2018 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 TK1332 6d45967d130f4f8fbec7b2c42971a8ee 1125 SUPERFAMILY SSF52540 736 797 1.79E-11 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK1332 6d45967d130f4f8fbec7b2c42971a8ee 1125 PRINTS PR00379 Intein signature 497 509 1.7E-9 T 31-10-2018 IPR006142 Intein GO:0016539 TK1332 6d45967d130f4f8fbec7b2c42971a8ee 1125 PRINTS PR00379 Intein signature 595 607 1.7E-9 T 31-10-2018 IPR006142 Intein GO:0016539 TK1332 6d45967d130f4f8fbec7b2c42971a8ee 1125 PRINTS PR00379 Intein signature 712 729 1.7E-9 T 31-10-2018 IPR006142 Intein GO:0016539 TK1332 6d45967d130f4f8fbec7b2c42971a8ee 1125 PRINTS PR00379 Intein signature 627 642 1.7E-9 T 31-10-2018 IPR006142 Intein GO:0016539 TK1332 6d45967d130f4f8fbec7b2c42971a8ee 1125 Gene3D G3DSA:3.10.28.10 482 685 3.7E-32 T 31-10-2018 IPR027434 Homing endonuclease TK1332 6d45967d130f4f8fbec7b2c42971a8ee 1125 SUPERFAMILY SSF52540 2 191 6.5E-47 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK1332 6d45967d130f4f8fbec7b2c42971a8ee 1125 SUPERFAMILY SSF55608 577 681 3.74E-17 T 31-10-2018 IPR027434 Homing endonuclease TK1332 6d45967d130f4f8fbec7b2c42971a8ee 1125 Pfam PF14520 Helix-hairpin-helix domain 1049 1098 9.5E-11 T 31-10-2018 TK1332 6d45967d130f4f8fbec7b2c42971a8ee 1125 SMART SM00487 20 204 4.0E-30 T 31-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TK1128 a19a287785de89cdb144482da2f27c84 94 Gene3D G3DSA:3.30.460.10 2 93 1.0E-15 T 31-10-2018 TK1128 a19a287785de89cdb144482da2f27c84 94 Pfam PF01909 Nucleotidyltransferase domain 9 88 2.5E-11 T 31-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 TK1128 a19a287785de89cdb144482da2f27c84 94 SUPERFAMILY SSF81301 4 94 1.71E-17 T 31-10-2018 TK1970 c34c12e25236f97720953fd6ab75691a 235 TIGRFAM TIGR00050 rRNA_methyl_1: RNA methyltransferase, TrmH family, group 1 1 227 1.6E-64 T 31-10-2018 IPR004384 RNA methyltransferase TrmJ/LasT GO:0006396|GO:0008173 TK1970 c34c12e25236f97720953fd6ab75691a 235 SUPERFAMILY SSF75217 3 176 1.05E-32 T 31-10-2018 IPR029028 Alpha/beta knot methyltransferases TK1970 c34c12e25236f97720953fd6ab75691a 235 PIRSF PIRSF004808 1 235 1.9E-75 T 31-10-2018 IPR004384 RNA methyltransferase TrmJ/LasT GO:0006396|GO:0008173 TK1970 c34c12e25236f97720953fd6ab75691a 235 Pfam PF00588 SpoU rRNA Methylase family 2 150 5.7E-34 T 31-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 TK1970 c34c12e25236f97720953fd6ab75691a 235 Gene3D G3DSA:3.40.1280.10 1 156 1.3E-48 T 31-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal TK1428 5a32321733665d556b4190f382389a08 648 SMART SM01027 433 557 2.4E-58 T 31-10-2018 IPR022712 Beta-Casp domain TK1428 5a32321733665d556b4190f382389a08 648 TIGRFAM TIGR03675 arCOG00543: arCOG00543 universal archaeal KH-domain/beta-lactamase-domain protein 13 647 3.3E-301 T 31-10-2018 IPR019975 KH-domain/beta-lactamase-domain protein, archaea TK1428 5a32321733665d556b4190f382389a08 648 Pfam PF16661 Metallo-beta-lactamase superfamily domain 203 351 2.8E-10 T 31-10-2018 IPR001279 Metallo-beta-lactamase TK1428 5a32321733665d556b4190f382389a08 648 Pfam PF10996 Beta-Casp domain 433 556 2.9E-25 T 31-10-2018 IPR022712 Beta-Casp domain TK1428 5a32321733665d556b4190f382389a08 648 Pfam PF17214 KH domain 9 76 6.8E-28 T 31-10-2018 IPR033769 KH domain, archaeal TK1428 5a32321733665d556b4190f382389a08 648 Gene3D G3DSA:3.60.15.10 191 627 3.3E-167 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TK1428 5a32321733665d556b4190f382389a08 648 SUPERFAMILY SSF56281 183 647 1.83E-133 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TK1428 5a32321733665d556b4190f382389a08 648 Gene3D G3DSA:3.40.50.10890 401 588 3.3E-167 T 31-10-2018 TK1428 5a32321733665d556b4190f382389a08 648 SMART SM00322 102 169 0.0017 T 31-10-2018 IPR004087 K Homology domain GO:0003676 TK1428 5a32321733665d556b4190f382389a08 648 SUPERFAMILY SSF54814 96 141 2.75E-5 T 31-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 TK1428 5a32321733665d556b4190f382389a08 648 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 576 639 2.8E-18 T 31-10-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain TK1428 5a32321733665d556b4190f382389a08 648 Gene3D G3DSA:3.30.300.230 17 176 2.5E-64 T 31-10-2018 TK1428 5a32321733665d556b4190f382389a08 648 Gene3D G3DSA:3.30.300.20 72 142 2.5E-64 T 31-10-2018 IPR015946 K homology domain-like, alpha/beta TK1428 5a32321733665d556b4190f382389a08 648 SMART SM00849 198 428 7.0E-25 T 31-10-2018 IPR001279 Metallo-beta-lactamase TK1307 8f47b6e7caf75b6475785f7313de69e2 174 Pfam PF00334 Nucleoside diphosphate kinase 7 143 2.3E-56 T 31-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TK1307 8f47b6e7caf75b6475785f7313de69e2 174 SMART SM00562 6 146 1.6E-81 T 31-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TK1307 8f47b6e7caf75b6475785f7313de69e2 174 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 6 144 35.722 T 31-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TK1307 8f47b6e7caf75b6475785f7313de69e2 174 ProSitePatterns PS00469 Nucleoside diphosphate kinases active site. 120 128 - T 31-10-2018 IPR023005 Nucleoside diphosphate kinase, active site KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TK1307 8f47b6e7caf75b6475785f7313de69e2 174 SUPERFAMILY SSF54919 6 152 8.25E-60 T 31-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TK1307 8f47b6e7caf75b6475785f7313de69e2 174 PRINTS PR01243 Nucleoside diphosphate kinase signature 73 90 6.8E-43 T 31-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TK1307 8f47b6e7caf75b6475785f7313de69e2 174 PRINTS PR01243 Nucleoside diphosphate kinase signature 9 31 6.8E-43 T 31-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TK1307 8f47b6e7caf75b6475785f7313de69e2 174 PRINTS PR01243 Nucleoside diphosphate kinase signature 53 72 6.8E-43 T 31-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TK1307 8f47b6e7caf75b6475785f7313de69e2 174 PRINTS PR01243 Nucleoside diphosphate kinase signature 94 110 6.8E-43 T 31-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TK1307 8f47b6e7caf75b6475785f7313de69e2 174 PRINTS PR01243 Nucleoside diphosphate kinase signature 120 139 6.8E-43 T 31-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TK1307 8f47b6e7caf75b6475785f7313de69e2 174 Gene3D G3DSA:3.30.70.141 1 159 7.7E-69 T 31-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TK1669 54849d97717f8e9cf2243161d4772397 380 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 5 168 1.1E-25 T 31-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TK1669 54849d97717f8e9cf2243161d4772397 380 SUPERFAMILY SSF52490 3 199 7.2E-41 T 31-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 TK1669 54849d97717f8e9cf2243161d4772397 380 Hamap MF_01946 Tubulin-like protein CetZ [cetZ]. 1 354 27.177 T 31-10-2018 IPR032907 Tubulin-like protein CetZ GO:0008360 TK1669 54849d97717f8e9cf2243161d4772397 380 SMART SM00864 2 199 6.2E-37 T 31-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TK1669 54849d97717f8e9cf2243161d4772397 380 PRINTS PR00423 Cell division protein FtsZ signature 183 205 5.2E-10 T 31-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TK1669 54849d97717f8e9cf2243161d4772397 380 PRINTS PR00423 Cell division protein FtsZ signature 93 113 5.2E-10 T 31-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TK1669 54849d97717f8e9cf2243161d4772397 380 PRINTS PR00423 Cell division protein FtsZ signature 123 144 5.2E-10 T 31-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TK1669 54849d97717f8e9cf2243161d4772397 380 Gene3D G3DSA:3.40.50.1440 1 363 1.2E-88 T 31-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 TK1669 54849d97717f8e9cf2243161d4772397 380 ProSitePatterns PS00227 Tubulin subunits alpha, beta, and gamma signature. 101 107 - T 31-10-2018 IPR017975 Tubulin, conserved site GO:0005525|GO:0005874|GO:0007017 Reactome: R-HSA-380320 TK0066 af39692f90fe424457473988cb969be7 154 SUPERFAMILY SSF88723 1 142 5.33E-22 T 31-10-2018 IPR029060 PIN-like domain superfamily TK0066 af39692f90fe424457473988cb969be7 154 SMART SM00670 2 133 2.4E-14 T 31-10-2018 IPR002716 PIN domain TK0066 af39692f90fe424457473988cb969be7 154 Pfam PF01850 PIN domain 4 135 9.9E-23 T 31-10-2018 IPR002716 PIN domain TK0066 af39692f90fe424457473988cb969be7 154 Gene3D G3DSA:3.40.50.1010 1 143 4.4E-13 T 31-10-2018 TK2245 c6cb85a1fd29b5b7908cb2709d53c7dc 304 SUPERFAMILY SSF109755 125 301 1.06E-17 T 31-10-2018 TK2245 c6cb85a1fd29b5b7908cb2709d53c7dc 304 Gene3D G3DSA:1.20.58.220 134 235 4.8E-11 T 31-10-2018 IPR038078 PhoU-like domain superfamily TK2245 c6cb85a1fd29b5b7908cb2709d53c7dc 304 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 8 50 3.5E-8 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 TK2245 c6cb85a1fd29b5b7908cb2709d53c7dc 304 Pfam PF01895 PhoU domain 138 230 1.2E-12 T 31-10-2018 IPR026022 PhoU domain TK2245 c6cb85a1fd29b5b7908cb2709d53c7dc 304 SMART SM00966 8 54 1.3E-9 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 TK1539 3ec2d6edad4c1082c92b328fe0381d52 239 Gene3D G3DSA:2.30.30.30 85 162 7.4E-30 T 31-10-2018 IPR014722 Ribosomal protein L2, domain 2 TK1539 3ec2d6edad4c1082c92b328fe0381d52 239 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 93 222 1.7E-42 T 31-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 TK1539 3ec2d6edad4c1082c92b328fe0381d52 239 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 11 84 2.7E-21 T 31-10-2018 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 TK1539 3ec2d6edad4c1082c92b328fe0381d52 239 SUPERFAMILY SSF50104 94 237 6.02E-48 T 31-10-2018 IPR008991 Translation protein SH3-like domain superfamily TK1539 3ec2d6edad4c1082c92b328fe0381d52 239 Hamap MF_01320_A 50S ribosomal protein L2 [rplB]. 1 238 42.564 T 31-10-2018 IPR023672 Ribosomal protein L2, archaeal-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1539 3ec2d6edad4c1082c92b328fe0381d52 239 SMART SM01382 91 223 7.0E-61 T 31-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 TK1539 3ec2d6edad4c1082c92b328fe0381d52 239 Gene3D G3DSA:2.40.50.140 1 81 5.0E-31 T 31-10-2018 TK1539 3ec2d6edad4c1082c92b328fe0381d52 239 PIRSF PIRSF002158 1 239 1.9E-72 T 31-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TK1539 3ec2d6edad4c1082c92b328fe0381d52 239 Gene3D G3DSA:4.10.950.10 163 239 3.4E-34 T 31-10-2018 IPR014726 Ribosomal protein L2, domain 3 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1539 3ec2d6edad4c1082c92b328fe0381d52 239 SUPERFAMILY SSF50249 2 92 1.95E-24 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold TK1539 3ec2d6edad4c1082c92b328fe0381d52 239 SMART SM01383 11 85 5.3E-28 T 31-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TK0754 b5a8360d2c51a8f5ca24caa37c5465d6 811 Gene3D G3DSA:3.40.50.12320 281 448 3.7E-33 T 31-10-2018 TK0754 b5a8360d2c51a8f5ca24caa37c5465d6 811 Hamap MF_01886 tRNA(Met) cytidine acetyltransferase TmcA [tmcA]. 39 807 47.913 T 31-10-2018 IPR024914 tRNA(Met) cytidine acetyltransferase TmcA GO:0000049|GO:0002101|GO:0051391|GO:0051392 TK0754 b5a8360d2c51a8f5ca24caa37c5465d6 811 Pfam PF05127 Helicase 285 458 3.5E-55 T 31-10-2018 IPR007807 Helicase domain Reactome: R-HSA-6790901 TK0754 b5a8360d2c51a8f5ca24caa37c5465d6 811 Pfam PF13718 GNAT acetyltransferase 2 499 615 1.3E-32 T 31-10-2018 IPR000182 GNAT domain TK0754 b5a8360d2c51a8f5ca24caa37c5465d6 811 SUPERFAMILY SSF52540 259 397 9.65E-8 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK0754 b5a8360d2c51a8f5ca24caa37c5465d6 811 Pfam PF08351 Domain of unknown function (DUF1726) 129 221 7.4E-33 T 31-10-2018 IPR013562 tRNA(Met) cytidine acetyltransferase TmcA, N-terminal Reactome: R-HSA-6790901 TK0754 b5a8360d2c51a8f5ca24caa37c5465d6 811 Gene3D G3DSA:3.40.630.30 456 662 3.7E-55 T 31-10-2018 TK0754 b5a8360d2c51a8f5ca24caa37c5465d6 811 Gene3D G3DSA:3.40.50.11040 24 253 2.1E-12 T 31-10-2018 TK0754 b5a8360d2c51a8f5ca24caa37c5465d6 811 SUPERFAMILY SSF55729 490 644 2.09E-10 T 31-10-2018 IPR016181 Acyl-CoA N-acyltransferase TK1178 c6f800c17d5d992ae7f5c78c345cf4b1 186 Hamap MF_01842 Archaemetzincin [amzA]. 2 179 38.187 T 31-10-2018 IPR012091 Peptidase M54, archaemetzincin, archaeal/bacterial GO:0006508|GO:0008237|GO:0008270 TK1178 c6f800c17d5d992ae7f5c78c345cf4b1 186 Pfam PF07998 Peptidase family M54 75 179 1.6E-31 T 31-10-2018 IPR012962 Peptidase M54, archaemetzincin GO:0008270 TK1178 c6f800c17d5d992ae7f5c78c345cf4b1 186 Gene3D G3DSA:3.40.390.10 34 179 2.2E-50 T 31-10-2018 IPR024079 Metallopeptidase, catalytic domain superfamily GO:0008237 TK1178 c6f800c17d5d992ae7f5c78c345cf4b1 186 PIRSF PIRSF005785 1 186 2.7E-69 T 31-10-2018 IPR012091 Peptidase M54, archaemetzincin, archaeal/bacterial GO:0006508|GO:0008237|GO:0008270 TK1178 c6f800c17d5d992ae7f5c78c345cf4b1 186 SUPERFAMILY SSF55486 71 174 4.05E-16 T 31-10-2018 TK1235 7f85fd7f4828a4af685198b26d7ccc33 642 SMART SM01016 8 95 2.2E-17 T 31-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 TK1235 7f85fd7f4828a4af685198b26d7ccc33 642 SUPERFAMILY SSF55190 7 116 1.14E-18 T 31-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 TK1235 7f85fd7f4828a4af685198b26d7ccc33 642 PRINTS PR01038 Arginyl-tRNA synthetase signature 330 351 1.8E-23 T 31-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 TK1235 7f85fd7f4828a4af685198b26d7ccc33 642 PRINTS PR01038 Arginyl-tRNA synthetase signature 125 140 1.8E-23 T 31-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 TK1235 7f85fd7f4828a4af685198b26d7ccc33 642 PRINTS PR01038 Arginyl-tRNA synthetase signature 164 177 1.8E-23 T 31-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 TK1235 7f85fd7f4828a4af685198b26d7ccc33 642 PRINTS PR01038 Arginyl-tRNA synthetase signature 140 156 1.8E-23 T 31-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 TK1235 7f85fd7f4828a4af685198b26d7ccc33 642 Gene3D G3DSA:1.10.730.10 524 642 3.8E-42 T 31-10-2018 TK1235 7f85fd7f4828a4af685198b26d7ccc33 642 Gene3D G3DSA:3.30.1360.70 6 121 1.4E-31 T 31-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 TK1235 7f85fd7f4828a4af685198b26d7ccc33 642 Hamap MF_00123 Arginine--tRNA ligase [argS]. 12 642 28.018 T 31-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 TK1235 7f85fd7f4828a4af685198b26d7ccc33 642 Pfam PF05746 DALR anticodon binding domain 520 642 1.3E-37 T 31-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 TK1235 7f85fd7f4828a4af685198b26d7ccc33 642 Pfam PF00750 tRNA synthetases class I (R) 105 363 2.4E-26 T 31-10-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 TK1235 7f85fd7f4828a4af685198b26d7ccc33 642 Pfam PF00750 tRNA synthetases class I (R) 388 494 4.3E-11 T 31-10-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 TK1235 7f85fd7f4828a4af685198b26d7ccc33 642 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 14 365 2.5E-80 T 31-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 TK1235 7f85fd7f4828a4af685198b26d7ccc33 642 SMART SM00836 520 642 5.9E-53 T 31-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 TK1235 7f85fd7f4828a4af685198b26d7ccc33 642 Gene3D G3DSA:3.40.50.620 122 523 2.2E-160 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TK1235 7f85fd7f4828a4af685198b26d7ccc33 642 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 135 144 - T 31-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 TK1235 7f85fd7f4828a4af685198b26d7ccc33 642 SUPERFAMILY SSF47323 515 642 2.16E-35 T 31-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 TK1235 7f85fd7f4828a4af685198b26d7ccc33 642 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 14 95 7.1E-13 T 31-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 TK1235 7f85fd7f4828a4af685198b26d7ccc33 642 SUPERFAMILY SSF52374 121 513 4.22E-77 T 31-10-2018 TK0817 6002442ac1c7d3647244be556244b179 570 SUPERFAMILY SSF52922 463 566 3.66E-12 T 31-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TK0817 6002442ac1c7d3647244be556244b179 570 Gene3D G3DSA:3.40.920.10 5 186 3.0E-25 T 31-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 TK0817 6002442ac1c7d3647244be556244b179 570 Gene3D G3DSA:3.40.50.920 459 570 4.2E-26 T 31-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TK0817 6002442ac1c7d3647244be556244b179 570 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 213 445 2.1E-58 T 31-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 TK0817 6002442ac1c7d3647244be556244b179 570 Gene3D G3DSA:3.40.50.970 187 389 3.3E-72 T 31-10-2018 TK0817 6002442ac1c7d3647244be556244b179 570 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 16 177 3.2E-31 T 31-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 TK0817 6002442ac1c7d3647244be556244b179 570 SUPERFAMILY SSF52518 201 449 1.33E-67 T 31-10-2018 IPR029061 Thiamin diphosphate-binding fold TK0817 6002442ac1c7d3647244be556244b179 570 TIGRFAM TIGR03710 OAFO_sf: 2-oxoacid:acceptor oxidoreductase, alpha subunit 7 564 3.8E-206 T 31-10-2018 IPR022367 2-oxoacid:acceptor oxidoreductase, alpha subunit KEGG: 00020+1.2.7.3|KEGG: 00720+1.2.7.3|MetaCyc: PWY-5392|MetaCyc: PWY-6969 TK0817 6002442ac1c7d3647244be556244b179 570 SUPERFAMILY SSF53323 8 222 5.1E-39 T 31-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 TK0160 92c5288a469db71daf8155975f67a4f1 344 Pfam PF03576 Peptidase family S58 19 324 6.9E-111 T 31-10-2018 IPR005321 Peptidase S58, DmpA TK0160 92c5288a469db71daf8155975f67a4f1 344 SUPERFAMILY SSF56266 2 340 5.49E-103 T 31-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 TK0160 92c5288a469db71daf8155975f67a4f1 344 Gene3D G3DSA:3.60.70.12 1 344 1.2E-135 T 31-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 TK0854 0fab632c96aeb0848cd312914cedce5e 483 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 5 229 2.5E-20 T 31-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain TK0854 0fab632c96aeb0848cd312914cedce5e 483 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 250 432 3.5E-51 T 31-10-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 TK0854 0fab632c96aeb0848cd312914cedce5e 483 SUPERFAMILY SSF52317 192 389 1.18E-29 T 31-10-2018 IPR029062 Class I glutamine amidotransferase-like TK0854 0fab632c96aeb0848cd312914cedce5e 483 SUPERFAMILY SSF52540 1 236 5.66E-52 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK0854 0fab632c96aeb0848cd312914cedce5e 483 TIGRFAM TIGR00313 cobQ: cobyric acid synthase CobQ 5 476 6.2E-161 T 31-10-2018 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 TK0854 0fab632c96aeb0848cd312914cedce5e 483 Gene3D G3DSA:3.40.50.300 1 240 3.8E-52 T 31-10-2018 TK0854 0fab632c96aeb0848cd312914cedce5e 483 Gene3D G3DSA:3.40.50.880 248 395 7.9E-16 T 31-10-2018 IPR029062 Class I glutamine amidotransferase-like TK0854 0fab632c96aeb0848cd312914cedce5e 483 Hamap MF_00028 Cobyric acid synthase [cobQ]. 1 483 166.109 T 31-10-2018 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 TK1722 e81853a86404139fe7ed782fbbf66b89 272 Gene3D G3DSA:3.90.550.10 1 199 1.7E-46 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TK1722 e81853a86404139fe7ed782fbbf66b89 272 SUPERFAMILY SSF53448 4 242 1.63E-49 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TK1722 e81853a86404139fe7ed782fbbf66b89 272 Pfam PF00535 Glycosyl transferase family 2 10 137 3.0E-30 T 31-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TK1973 09f4f70ec21cbc00ca4132d02b05c464 111 Gene3D G3DSA:2.20.70.30 10 69 2.3E-22 T 31-10-2018 IPR038187 NAC A/B domain superfamily TK1973 09f4f70ec21cbc00ca4132d02b05c464 111 Hamap MF_00814 Nascent polypeptide-associated complex protein [nac]. 7 109 21.974 T 31-10-2018 IPR005231 Nascent polypeptide-associated complex (NAC), archaeal GO:0003723 TK1973 09f4f70ec21cbc00ca4132d02b05c464 111 SMART SM01407 6 66 2.9E-18 T 31-10-2018 IPR002715 Nascent polypeptide-associated complex NAC domain TK1973 09f4f70ec21cbc00ca4132d02b05c464 111 TIGRFAM TIGR00264 TIGR00264: alpha-NAC homolog 3 110 3.6E-38 T 31-10-2018 IPR005231 Nascent polypeptide-associated complex (NAC), archaeal GO:0003723 TK1973 09f4f70ec21cbc00ca4132d02b05c464 111 SUPERFAMILY SSF46934 69 110 3.94E-8 T 31-10-2018 IPR009060 UBA-like superfamily GO:0005515 TK1973 09f4f70ec21cbc00ca4132d02b05c464 111 Pfam PF01849 NAC domain 6 62 3.8E-12 T 31-10-2018 IPR002715 Nascent polypeptide-associated complex NAC domain TK1973 09f4f70ec21cbc00ca4132d02b05c464 111 Gene3D G3DSA:1.10.8.10 70 109 1.1E-20 T 31-10-2018 TK0942 278581482220cee9591a64e008c510dd 306 Pfam PF00005 ABC transporter 17 167 3.1E-30 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TK0942 278581482220cee9591a64e008c510dd 306 Pfam PF13732 Domain of unknown function (DUF4162) 221 304 2.3E-7 T 31-10-2018 IPR025302 Domain of unknown function DUF4162 TK0942 278581482220cee9591a64e008c510dd 306 SUPERFAMILY SSF52540 2 229 1.3E-57 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK0942 278581482220cee9591a64e008c510dd 306 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TK0942 278581482220cee9591a64e008c510dd 306 Gene3D G3DSA:3.40.50.300 1 241 8.7E-61 T 31-10-2018 TK0942 278581482220cee9591a64e008c510dd 306 SMART SM00382 26 219 8.0E-13 T 31-10-2018 IPR003593 AAA+ ATPase domain TK1325 76d6eb56cd85d2edc14cdfd66611d055 481 Gene3D G3DSA:1.10.1060.10 4 150 2.0E-39 T 31-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 TK1325 76d6eb56cd85d2edc14cdfd66611d055 481 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 399 415 5.3E-24 T 31-10-2018 TK1325 76d6eb56cd85d2edc14cdfd66611d055 481 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 425 447 5.3E-24 T 31-10-2018 TK1325 76d6eb56cd85d2edc14cdfd66611d055 481 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 159 178 5.3E-24 T 31-10-2018 TK1325 76d6eb56cd85d2edc14cdfd66611d055 481 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 297 315 5.3E-24 T 31-10-2018 TK1325 76d6eb56cd85d2edc14cdfd66611d055 481 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 158 456 2.1E-39 T 31-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TK1325 76d6eb56cd85d2edc14cdfd66611d055 481 SUPERFAMILY SSF46548 5 167 8.37E-33 T 31-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 TK1325 76d6eb56cd85d2edc14cdfd66611d055 481 Gene3D G3DSA:3.50.50.60 293 481 1.6E-30 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TK1325 76d6eb56cd85d2edc14cdfd66611d055 481 Gene3D G3DSA:3.50.50.60 153 282 3.2E-38 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TK1325 76d6eb56cd85d2edc14cdfd66611d055 481 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 21 139 1.1E-38 T 31-10-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 TK1325 76d6eb56cd85d2edc14cdfd66611d055 481 TIGRFAM TIGR01316 gltA: glutamate synthase (NADPH), homotetrameric 17 471 5.0E-211 T 31-10-2018 IPR006004 Glutamate synthase (NADPH), homotetrameric KEGG: 00195+1.18.1.2|MetaCyc: PWY-101 TK1325 76d6eb56cd85d2edc14cdfd66611d055 481 SUPERFAMILY SSF51971 156 407 3.94E-72 T 31-10-2018 TK1325 76d6eb56cd85d2edc14cdfd66611d055 481 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 440 447 6.0E-18 T 31-10-2018 TK1325 76d6eb56cd85d2edc14cdfd66611d055 481 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 158 180 6.0E-18 T 31-10-2018 TK1325 76d6eb56cd85d2edc14cdfd66611d055 481 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 297 322 6.0E-18 T 31-10-2018 TK1325 76d6eb56cd85d2edc14cdfd66611d055 481 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 400 414 6.0E-18 T 31-10-2018 TK1577 84f2c349d7531ae4c4e4a79226abd509 645 Gene3D G3DSA:2.60.40.1120 312 394 1.9E-11 T 31-10-2018 TK1577 84f2c349d7531ae4c4e4a79226abd509 645 Pfam PF10633 NPCBM-associated, NEW3 domain of alpha-galactosidase 119 192 1.1E-5 T 31-10-2018 IPR018905 Alpha-galactosidase, NEW3 domain TK1577 84f2c349d7531ae4c4e4a79226abd509 645 Pfam PF10633 NPCBM-associated, NEW3 domain of alpha-galactosidase 524 599 2.2E-15 T 31-10-2018 IPR018905 Alpha-galactosidase, NEW3 domain TK1577 84f2c349d7531ae4c4e4a79226abd509 645 SUPERFAMILY SSF49452 309 391 1.67E-9 T 31-10-2018 IPR013784 Carbohydrate-binding-like fold GO:0030246 TK1577 84f2c349d7531ae4c4e4a79226abd509 645 Pfam PF13620 Carboxypeptidase regulatory-like domain 313 391 1.6E-11 T 31-10-2018 TK1572 93f8e4559601abaaeca19ead55e3a534 250 TIGRFAM TIGR00486 YbgI_SA1388: dinuclear metal center protein, YbgI/SA1388 family 1 248 7.3E-62 T 31-10-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 TK1572 93f8e4559601abaaeca19ead55e3a534 250 Gene3D G3DSA:3.40.1390.30 6 238 1.8E-75 T 31-10-2018 TK1572 93f8e4559601abaaeca19ead55e3a534 250 SUPERFAMILY SSF102705 1 245 5.36E-71 T 31-10-2018 IPR036069 GTP cyclohydrolase 1 type 2/Nif3 superfamily TK1572 93f8e4559601abaaeca19ead55e3a534 250 Gene3D G3DSA:3.40.1390.30 96 221 1.8E-75 T 31-10-2018 TK1572 93f8e4559601abaaeca19ead55e3a534 250 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 5 237 5.2E-57 T 31-10-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 TK1607 8398cf84ca5b2afa0d6c62696d9a17f4 406 Pfam PF01411 tRNA synthetases class II (A) 18 95 1.3E-11 T 31-10-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 TK1607 8398cf84ca5b2afa0d6c62696d9a17f4 406 Pfam PF02272 DHHA1 domain 271 389 2.7E-13 T 31-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 TK1607 8398cf84ca5b2afa0d6c62696d9a17f4 406 Gene3D G3DSA:3.10.310.40 302 403 1.5E-7 T 31-10-2018 TK1607 8398cf84ca5b2afa0d6c62696d9a17f4 406 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 191 234 3.5E-11 T 31-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 TK1607 8398cf84ca5b2afa0d6c62696d9a17f4 406 SMART SM00863 191 234 5.0E-14 T 31-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 TK1607 8398cf84ca5b2afa0d6c62696d9a17f4 406 SUPERFAMILY SSF55186 93 238 1.12E-36 T 31-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 TK1607 8398cf84ca5b2afa0d6c62696d9a17f4 406 Gene3D G3DSA:2.40.30.130 1 84 5.2E-21 T 31-10-2018 TK1607 8398cf84ca5b2afa0d6c62696d9a17f4 406 Gene3D G3DSA:3.30.980.10 93 247 5.7E-42 T 31-10-2018 TK1607 8398cf84ca5b2afa0d6c62696d9a17f4 406 SUPERFAMILY SSF50447 1 90 7.06E-15 T 31-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily TK0318 25492affdb6a17566ce64a24a4207d5f 99 Pfam PF11505 Protein of unknown function (DUF3216) 7 97 1.9E-46 T 31-10-2018 IPR023108 Domain of unknown function, DUF3216 TK0318 25492affdb6a17566ce64a24a4207d5f 99 Gene3D G3DSA:1.20.120.460 3 99 3.7E-34 T 31-10-2018 IPR038317 Pf1176-like superfamily TK1817 7d52aed26a29f53bbf5025ed3fc3f9bf 286 Pfam PF16916 Dimerisation domain of Zinc Transporter 207 280 6.7E-23 T 31-10-2018 IPR027470 Cation efflux protein, cytoplasmic domain TK1817 7d52aed26a29f53bbf5025ed3fc3f9bf 286 Pfam PF01545 Cation efflux family 8 200 5.5E-45 T 31-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 TK1817 7d52aed26a29f53bbf5025ed3fc3f9bf 286 SUPERFAMILY SSF161111 5 202 5.89E-56 T 31-10-2018 IPR027469 Cation efflux transmembrane domain superfamily TK1817 7d52aed26a29f53bbf5025ed3fc3f9bf 286 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 6 281 2.0E-81 T 31-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 TK1817 7d52aed26a29f53bbf5025ed3fc3f9bf 286 Gene3D G3DSA:1.20.1510.10 4 200 3.5E-62 T 31-10-2018 IPR027469 Cation efflux transmembrane domain superfamily TK1817 7d52aed26a29f53bbf5025ed3fc3f9bf 286 SUPERFAMILY SSF160240 205 280 4.84E-22 T 31-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 TK1817 7d52aed26a29f53bbf5025ed3fc3f9bf 286 Gene3D G3DSA:3.30.70.1350 207 282 2.7E-21 T 31-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 TK0452 02be0d78fea1ea8c79cd933f31a8cd9c 247 TIGRFAM TIGR01874 cas_cas5a: CRISPR-associated protein Cas5, subtype I-A/APERN 26 187 5.9E-13 T 31-10-2018 IPR010153 CRISPR-associated protein, Cas5a type TK0452 02be0d78fea1ea8c79cd933f31a8cd9c 247 Gene3D G3DSA:3.30.70.3120 19 245 1.2E-18 T 31-10-2018 TK2070 398dc24bfa2c7e158e04ece85975a3df 264 SUPERFAMILY SSF56770 4 211 1.07E-46 T 31-10-2018 TK2070 398dc24bfa2c7e158e04ece85975a3df 264 Gene3D G3DSA:3.40.50.700 4 163 5.6E-42 T 31-10-2018 IPR037024 [NiFe]-hydrogenase, small subunit, N-terminal domain superfamily TK2070 398dc24bfa2c7e158e04ece85975a3df 264 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 16 152 2.7E-26 T 31-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TK0694 dba09c467657d49b1c099789837031c6 283 ProSitePatterns PS00211 ABC transporters family signature. 130 144 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TK0694 dba09c467657d49b1c099789837031c6 283 Gene3D G3DSA:3.40.50.300 1 234 6.3E-58 T 31-10-2018 TK0694 dba09c467657d49b1c099789837031c6 283 SMART SM00382 28 214 6.4E-11 T 31-10-2018 IPR003593 AAA+ ATPase domain TK0694 dba09c467657d49b1c099789837031c6 283 SUPERFAMILY SSF52540 2 217 7.04E-57 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK0694 dba09c467657d49b1c099789837031c6 283 Pfam PF00005 ABC transporter 20 157 1.8E-27 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TK1108 b5444bcb3d7c9d658cc8758206b56c77 456 TIGRFAM TIGR03990 Arch_GlmM: phosphoglucosamine mutase 3 448 2.3E-180 T 31-10-2018 IPR024086 Phosphoglucosamine mutase, archaeal type GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TK1108 b5444bcb3d7c9d658cc8758206b56c77 456 SUPERFAMILY SSF53738 155 259 9.03E-31 T 31-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TK1108 b5444bcb3d7c9d658cc8758206b56c77 456 SUPERFAMILY SSF53738 3 180 7.46E-48 T 31-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TK1108 b5444bcb3d7c9d658cc8758206b56c77 456 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 236 251 7.0E-18 T 31-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TK1108 b5444bcb3d7c9d658cc8758206b56c77 456 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 208 221 7.0E-18 T 31-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TK1108 b5444bcb3d7c9d658cc8758206b56c77 456 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 174 193 7.0E-18 T 31-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TK1108 b5444bcb3d7c9d658cc8758206b56c77 456 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 94 108 7.0E-18 T 31-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TK1108 b5444bcb3d7c9d658cc8758206b56c77 456 SUPERFAMILY SSF55957 358 455 2.88E-24 T 31-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TK1108 b5444bcb3d7c9d658cc8758206b56c77 456 Gene3D G3DSA:3.40.120.10 169 358 1.8E-77 T 31-10-2018 TK1108 b5444bcb3d7c9d658cc8758206b56c77 456 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 3 137 1.1E-47 T 31-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TK1108 b5444bcb3d7c9d658cc8758206b56c77 456 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 261 370 2.6E-27 T 31-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TK1108 b5444bcb3d7c9d658cc8758206b56c77 456 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 156 256 3.2E-30 T 31-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TK1108 b5444bcb3d7c9d658cc8758206b56c77 456 Gene3D G3DSA:3.40.120.10 1 152 1.4E-64 T 31-10-2018 TK1108 b5444bcb3d7c9d658cc8758206b56c77 456 Gene3D G3DSA:3.40.120.10 257 365 1.8E-77 T 31-10-2018 TK1108 b5444bcb3d7c9d658cc8758206b56c77 456 Gene3D G3DSA:3.30.310.50 371 455 1.0E-32 T 31-10-2018 TK1108 b5444bcb3d7c9d658cc8758206b56c77 456 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 379 443 1.1E-12 T 31-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TK1108 b5444bcb3d7c9d658cc8758206b56c77 456 SUPERFAMILY SSF53738 261 367 2.2E-26 T 31-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TK2147 d283b92f5323a3f03d01d53e8baa3998 769 Gene3D G3DSA:1.10.287.950 462 768 3.5E-65 T 31-10-2018 TK2147 d283b92f5323a3f03d01d53e8baa3998 769 Gene3D G3DSA:3.30.450.20 208 300 3.7E-44 T 31-10-2018 TK2147 d283b92f5323a3f03d01d53e8baa3998 769 Pfam PF02743 Cache domain 63 297 6.7E-42 T 31-10-2018 IPR033479 Double Cache domain 1 TK2147 d283b92f5323a3f03d01d53e8baa3998 769 Pfam PF00672 HAMP domain 362 411 1.9E-6 T 31-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TK2147 d283b92f5323a3f03d01d53e8baa3998 769 SUPERFAMILY SSF58104 432 768 4.71E-62 T 31-10-2018 TK2147 d283b92f5323a3f03d01d53e8baa3998 769 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 591 618 2.0E-22 T 31-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TK2147 d283b92f5323a3f03d01d53e8baa3998 769 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 620 649 2.0E-22 T 31-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TK2147 d283b92f5323a3f03d01d53e8baa3998 769 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 514 543 2.0E-22 T 31-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TK2147 d283b92f5323a3f03d01d53e8baa3998 769 Gene3D G3DSA:3.30.450.20 126 207 3.7E-44 T 31-10-2018 TK2147 d283b92f5323a3f03d01d53e8baa3998 769 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 555 689 5.1E-38 T 31-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TK2147 d283b92f5323a3f03d01d53e8baa3998 769 SMART SM00304 457 510 38.0 T 31-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TK2147 d283b92f5323a3f03d01d53e8baa3998 769 SMART SM00304 361 419 7.2E-5 T 31-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TK2147 d283b92f5323a3f03d01d53e8baa3998 769 SMART SM00304 709 765 51.0 T 31-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TK2147 d283b92f5323a3f03d01d53e8baa3998 769 SMART SM00283 493 768 7.6E-67 T 31-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TK2147 d283b92f5323a3f03d01d53e8baa3998 769 Gene3D G3DSA:1.20.1480.50 321 426 4.2E-7 T 31-10-2018 TK2147 d283b92f5323a3f03d01d53e8baa3998 769 SUPERFAMILY SSF103190 122 217 1.05E-14 T 31-10-2018 IPR029151 Periplasmic sensor-like domain superfamily TK0635 782d4b8fb9bfa0eeec871a48d8eb63ad 231 SUPERFAMILY SSF50341 94 224 2.49E-35 T 31-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 TK0635 782d4b8fb9bfa0eeec871a48d8eb63ad 231 Pfam PF01584 CheW-like domain 99 225 7.3E-28 T 31-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 TK0635 782d4b8fb9bfa0eeec871a48d8eb63ad 231 SMART SM00260 87 224 7.5E-42 T 31-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 TK0635 782d4b8fb9bfa0eeec871a48d8eb63ad 231 Gene3D G3DSA:2.30.30.40 95 220 6.5E-41 T 31-10-2018 TK0635 782d4b8fb9bfa0eeec871a48d8eb63ad 231 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 1 92 2.4E-12 T 31-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TK0635 782d4b8fb9bfa0eeec871a48d8eb63ad 231 Gene3D G3DSA:2.40.50.180 118 179 6.5E-41 T 31-10-2018 TK0635 782d4b8fb9bfa0eeec871a48d8eb63ad 231 SUPERFAMILY SSF55874 1 92 3.41E-24 T 31-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TK0635 782d4b8fb9bfa0eeec871a48d8eb63ad 231 PRINTS PR00344 Bacterial sensor protein C-terminal signature 39 49 4.2E-10 T 31-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TK0635 782d4b8fb9bfa0eeec871a48d8eb63ad 231 PRINTS PR00344 Bacterial sensor protein C-terminal signature 79 92 4.2E-10 T 31-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TK0635 782d4b8fb9bfa0eeec871a48d8eb63ad 231 PRINTS PR00344 Bacterial sensor protein C-terminal signature 55 73 4.2E-10 T 31-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TK0635 782d4b8fb9bfa0eeec871a48d8eb63ad 231 Gene3D G3DSA:3.30.565.10 1 94 1.6E-30 T 31-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TK0457 78714799df26cad2601b7630d9daa8ac 75 Gene3D G3DSA:2.10.260.10 2 42 2.8E-16 T 31-10-2018 TK0457 78714799df26cad2601b7630d9daa8ac 75 SMART SM00966 4 49 2.6E-14 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 TK0457 78714799df26cad2601b7630d9daa8ac 75 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 5 48 2.4E-14 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 TK0457 78714799df26cad2601b7630d9daa8ac 75 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 4 43 2.1E-15 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 TK0457 78714799df26cad2601b7630d9daa8ac 75 SUPERFAMILY SSF89447 1 62 1.6E-13 T 31-10-2018 IPR037914 SpoVT-AbrB domain superfamily TK0724 70e270895d73cb30008d28bc81e45018 207 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 13 107 8.3E-23 T 31-10-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis TK0724 70e270895d73cb30008d28bc81e45018 207 Gene3D G3DSA:3.30.420.130 1 118 3.0E-27 T 31-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily TK0724 70e270895d73cb30008d28bc81e45018 207 SUPERFAMILY SSF53146 1 117 6.15E-28 T 31-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily TK1883 8d0f5ddd592893a4becbe0bfe5aafc12 185 Gene3D G3DSA:1.10.10.10 1 85 2.4E-23 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TK1883 8d0f5ddd592893a4becbe0bfe5aafc12 185 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 45 60 6.9E-5 T 31-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TK1883 8d0f5ddd592893a4becbe0bfe5aafc12 185 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 13 28 6.9E-5 T 31-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TK1883 8d0f5ddd592893a4becbe0bfe5aafc12 185 SUPERFAMILY SSF46785 1 130 2.6E-25 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TK1883 8d0f5ddd592893a4becbe0bfe5aafc12 185 SMART SM00418 11 86 9.0E-14 T 31-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TK1883 8d0f5ddd592893a4becbe0bfe5aafc12 185 Pfam PF01022 Bacterial regulatory protein, arsR family 18 63 8.9E-15 T 31-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TK1266 74d65ab9190e22167ddcab8bd1728f0a 192 Gene3D G3DSA:3.10.580.10 65 186 1.3E-27 T 31-10-2018 TK1266 74d65ab9190e22167ddcab8bd1728f0a 192 Gene3D G3DSA:1.10.260.40 10 63 3.3E-17 T 31-10-2018 TK1266 74d65ab9190e22167ddcab8bd1728f0a 192 Pfam PF00571 CBS domain 70 121 9.7E-14 T 31-10-2018 IPR000644 CBS domain TK1266 74d65ab9190e22167ddcab8bd1728f0a 192 Pfam PF00571 CBS domain 136 184 4.0E-7 T 31-10-2018 IPR000644 CBS domain TK1266 74d65ab9190e22167ddcab8bd1728f0a 192 SMART SM00116 77 124 2.0E-8 T 31-10-2018 IPR000644 CBS domain TK1266 74d65ab9190e22167ddcab8bd1728f0a 192 SMART SM00116 141 187 0.19 T 31-10-2018 IPR000644 CBS domain TK1266 74d65ab9190e22167ddcab8bd1728f0a 192 SMART SM00530 12 66 4.0E-14 T 31-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TK1266 74d65ab9190e22167ddcab8bd1728f0a 192 SUPERFAMILY SSF47413 11 60 1.39E-14 T 31-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TK1266 74d65ab9190e22167ddcab8bd1728f0a 192 PIRSF PIRSF037253 2 190 1.5E-85 T 31-10-2018 IPR017158 Transcription regulator, CBS domain-containing, predicted TK1266 74d65ab9190e22167ddcab8bd1728f0a 192 Pfam PF01381 Helix-turn-helix 13 60 2.2E-15 T 31-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TK1266 74d65ab9190e22167ddcab8bd1728f0a 192 SUPERFAMILY SSF54631 69 184 3.54E-27 T 31-10-2018 TK0665 fd9f9d70d61662dbe6fd2c44c10ad84b 465 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 159 296 4.1E-57 T 31-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain TK0665 fd9f9d70d61662dbe6fd2c44c10ad84b 465 SUPERFAMILY SSF51735 6 137 4.51E-38 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily TK0665 fd9f9d70d61662dbe6fd2c44c10ad84b 465 Gene3D G3DSA:3.40.50.720 4 137 2.8E-45 T 31-10-2018 TK0665 fd9f9d70d61662dbe6fd2c44c10ad84b 465 Pfam PF13380 CoA binding domain 13 142 1.4E-20 T 31-10-2018 IPR003781 CoA-binding GO:0048037 TK0665 fd9f9d70d61662dbe6fd2c44c10ad84b 465 SMART SM00881 9 108 5.1E-39 T 31-10-2018 IPR003781 CoA-binding GO:0048037 TK0665 fd9f9d70d61662dbe6fd2c44c10ad84b 465 SUPERFAMILY SSF52210 139 298 4.32E-45 T 31-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TK0665 fd9f9d70d61662dbe6fd2c44c10ad84b 465 Gene3D G3DSA:3.40.50.261 300 465 2.5E-50 T 31-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TK0665 fd9f9d70d61662dbe6fd2c44c10ad84b 465 Gene3D G3DSA:3.40.50.261 138 299 5.2E-66 T 31-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TK0665 fd9f9d70d61662dbe6fd2c44c10ad84b 465 SUPERFAMILY SSF52210 302 460 1.15E-33 T 31-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TK0665 fd9f9d70d61662dbe6fd2c44c10ad84b 465 TIGRFAM TIGR02717 AcCoA-syn-alpha: acetyl coenzyme A synthetase (ADP forming), alpha domain 7 455 2.4E-186 T 31-10-2018 IPR014089 Acetate-CoA ligase [ADP-forming], alpha domain KEGG: 00010+6.2.1.13|KEGG: 00620+6.2.1.13|KEGG: 00640+6.2.1.13|MetaCyc: PWY-5483|MetaCyc: PWY-5535 TK1732 209a0b88ab002a04f501e60c5dfafba1 373 Gene3D G3DSA:3.90.550.10 1 225 2.7E-53 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TK1732 209a0b88ab002a04f501e60c5dfafba1 373 Pfam PF00535 Glycosyl transferase family 2 6 167 6.0E-26 T 31-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TK1732 209a0b88ab002a04f501e60c5dfafba1 373 SUPERFAMILY SSF53448 4 246 1.39E-41 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TK0639 a73288b69f6ed1b6e59414318ff696f3 161 Gene3D G3DSA:3.30.1330.200 1 159 2.1E-54 T 31-10-2018 IPR038592 CheD-like superfamily TK0639 a73288b69f6ed1b6e59414318ff696f3 161 SUPERFAMILY SSF64438 2 154 4.3E-49 T 31-10-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic TK0639 a73288b69f6ed1b6e59414318ff696f3 161 Pfam PF03975 CheD chemotactic sensory transduction 46 150 1.0E-35 T 31-10-2018 IPR005659 Chemoreceptor glutamine deamidase CheD GO:0006935|GO:0050568 TK0639 a73288b69f6ed1b6e59414318ff696f3 161 Hamap MF_01440 Chemoreceptor glutamine deamidase CheD [cheD]. 1 154 27.267 T 31-10-2018 IPR005659 Chemoreceptor glutamine deamidase CheD GO:0006935|GO:0050568 TK2043 7d57d9b4f42bb8e51581ac6968367f34 203 Gene3D G3DSA:3.40.50.11570 2 202 1.7E-35 T 31-10-2018 TK2043 7d57d9b4f42bb8e51581ac6968367f34 203 Pfam PF03192 Pyrococcus protein of unknown function, DUF257 12 185 2.3E-29 T 31-10-2018 IPR005489 Protein of unknown function DUF257 TK1396 4db6e7a1a41e604939454116af4a536a 497 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 132 144 - T 31-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 TK1396 4db6e7a1a41e604939454116af4a536a 497 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 355 375 - T 31-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 TK1396 4db6e7a1a41e604939454116af4a536a 497 PIRSF PIRSF000538 2 492 2.0E-179 T 31-10-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 TK1396 4db6e7a1a41e604939454116af4a536a 497 SUPERFAMILY SSF53067 249 487 2.27E-82 T 31-10-2018 TK1396 4db6e7a1a41e604939454116af4a536a 497 Hamap MF_00186 Glycerol kinase [glpK]. 2 488 57.266 T 31-10-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 TK1396 4db6e7a1a41e604939454116af4a536a 497 Gene3D G3DSA:3.30.420.40 1 247 7.9E-118 T 31-10-2018 TK1396 4db6e7a1a41e604939454116af4a536a 497 TIGRFAM TIGR01311 glycerol_kin: glycerol kinase 3 487 1.2E-216 T 31-10-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 TK1396 4db6e7a1a41e604939454116af4a536a 497 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 5 246 1.7E-88 T 31-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 TK1396 4db6e7a1a41e604939454116af4a536a 497 SUPERFAMILY SSF53067 4 248 2.87E-96 T 31-10-2018 TK1396 4db6e7a1a41e604939454116af4a536a 497 Gene3D G3DSA:3.30.420.40 248 497 2.7E-95 T 31-10-2018 TK1396 4db6e7a1a41e604939454116af4a536a 497 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 256 441 2.0E-56 T 31-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 TK2062 3aaa5aa8c1a3b8a60b7c3748e0eb6637 549 Gene3D G3DSA:3.60.21.10 325 534 9.9E-22 T 31-10-2018 IPR029052 Metallo-dependent phosphatase-like TK2062 3aaa5aa8c1a3b8a60b7c3748e0eb6637 549 Pfam PF00149 Calcineurin-like phosphoesterase 320 497 4.6E-14 T 31-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 TK2062 3aaa5aa8c1a3b8a60b7c3748e0eb6637 549 SUPERFAMILY SSF56300 324 531 1.65E-37 T 31-10-2018 TK1054 cec7f0678423239fa8cd4d31f3a0093e 177 Gene3D G3DSA:3.30.1990.20 145 176 1.3E-7 T 31-10-2018 TK1054 cec7f0678423239fa8cd4d31f3a0093e 177 Gene3D G3DSA:3.40.630.30 2 144 6.2E-68 T 31-10-2018 TK1054 cec7f0678423239fa8cd4d31f3a0093e 177 SUPERFAMILY SSF55729 14 167 2.95E-26 T 31-10-2018 IPR016181 Acyl-CoA N-acyltransferase TK1054 cec7f0678423239fa8cd4d31f3a0093e 177 Pfam PF00583 Acetyltransferase (GNAT) family 35 160 3.2E-16 T 31-10-2018 IPR000182 GNAT domain TK1164 19f865ab40446d8039889374b932fc7c 334 Gene3D G3DSA:3.90.226.10 90 288 3.6E-54 T 31-10-2018 TK1164 19f865ab40446d8039889374b932fc7c 334 Gene3D G3DSA:3.40.1750.20 186 252 3.6E-54 T 31-10-2018 TK1164 19f865ab40446d8039889374b932fc7c 334 TIGRFAM TIGR00706 SppA_dom: signal peptide peptidase SppA, 36K type 88 293 1.2E-68 T 31-10-2018 IPR004635 Peptidase S49, SppA GO:0006508|GO:0008233 TK1164 19f865ab40446d8039889374b932fc7c 334 SUPERFAMILY SSF52096 85 283 9.94E-36 T 31-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TK1164 19f865ab40446d8039889374b932fc7c 334 Pfam PF01343 Peptidase family S49 147 295 1.9E-41 T 31-10-2018 IPR002142 Peptidase S49 GO:0006508|GO:0008233 TK1547 df4d15a1084c1bbe0d88957d62976b02 387 Gene3D G3DSA:1.20.1250.20 2 380 2.6E-25 T 31-10-2018 TK1547 df4d15a1084c1bbe0d88957d62976b02 387 SUPERFAMILY SSF103473 3 376 6.28E-29 T 31-10-2018 IPR036259 MFS transporter superfamily TK1547 df4d15a1084c1bbe0d88957d62976b02 387 Pfam PF07690 Major Facilitator Superfamily 13 342 5.1E-17 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TK0359 2c43f260615c5098a82b901c73804811 150 Pfam PF13636 RNA-binding PUA-like domain of methyltransferase RsmF 99 146 4.6E-15 T 31-10-2018 IPR027391 rRNA small subunit methyltransferase F, RNA-binding PUA-like domain TK0359 2c43f260615c5098a82b901c73804811 150 Gene3D G3DSA:2.30.130.60 90 148 1.3E-8 T 31-10-2018 TK1432 177486cf2dad7fb5f905a729ce06c786 519 SUPERFAMILY SSF161070 5 492 3.01E-99 T 31-10-2018 IPR037272 Sodium:neurotransmitter symporter superfamily GO:0005328 TK1432 177486cf2dad7fb5f905a729ce06c786 519 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 182 199 2.5E-12 T 31-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 TK1432 177486cf2dad7fb5f905a729ce06c786 519 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 13 34 2.5E-12 T 31-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 TK1432 177486cf2dad7fb5f905a729ce06c786 519 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 42 61 2.5E-12 T 31-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 TK1432 177486cf2dad7fb5f905a729ce06c786 519 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 338 357 2.5E-12 T 31-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 TK1432 177486cf2dad7fb5f905a729ce06c786 519 Pfam PF00209 Sodium:neurotransmitter symporter family 5 131 2.0E-19 T 31-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 TK1432 177486cf2dad7fb5f905a729ce06c786 519 Pfam PF00209 Sodium:neurotransmitter symporter family 145 494 5.6E-21 T 31-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 TK1791 9df5a1c8369d29b43901f3c84b609a88 346 SUPERFAMILY SSF56747 5 341 2.4E-96 T 31-10-2018 TK1791 9df5a1c8369d29b43901f3c84b609a88 346 TIGRFAM TIGR00335 primase_sml: putative DNA primase, eukaryotic-type, small subunit 12 331 9.5E-59 T 31-10-2018 IPR014052 DNA primase, small subunit, eukaryotic/archaeal GO:0003896|GO:0006269 Reactome: R-HSA-113501|Reactome: R-HSA-174411|Reactome: R-HSA-174430|Reactome: R-HSA-68952|Reactome: R-HSA-68962|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183 TK1791 9df5a1c8369d29b43901f3c84b609a88 346 Hamap MF_00700 DNA primase small subunit PriS [priS]. 11 345 23.502 T 31-10-2018 IPR023639 DNA primase small subunit PriS GO:0003896 TK1791 9df5a1c8369d29b43901f3c84b609a88 346 Gene3D G3DSA:3.90.920.10 9 328 1.8E-124 T 31-10-2018 TK1791 9df5a1c8369d29b43901f3c84b609a88 346 Gene3D G3DSA:1.10.8.160 176 279 1.8E-124 T 31-10-2018 TK1791 9df5a1c8369d29b43901f3c84b609a88 346 Pfam PF01896 DNA primase small subunit 96 308 1.9E-14 T 31-10-2018 IPR002755 DNA primase, small subunit GO:0003896|GO:0006269 Reactome: R-HSA-113501|Reactome: R-HSA-174411|Reactome: R-HSA-174430|Reactome: R-HSA-68952|Reactome: R-HSA-68962|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183 TK0866 2b424791471c5eabd5f4cea50f466782 411 Pfam PF01676 Metalloenzyme superfamily 5 400 8.3E-56 T 31-10-2018 IPR006124 Metalloenzyme GO:0003824|GO:0046872 TK0866 2b424791471c5eabd5f4cea50f466782 411 SUPERFAMILY SSF53649 4 404 5.15E-47 T 31-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 TK0866 2b424791471c5eabd5f4cea50f466782 411 TIGRFAM TIGR00306 apgM: phosphoglycerate mutase (2,3-diphosphoglycerate-independent), archaeal form 7 401 5.9E-139 T 31-10-2018 IPR004456 2,3-bisphosphoglycerate-independent phosphoglycerate mutase GO:0003824|GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TK0866 2b424791471c5eabd5f4cea50f466782 411 Pfam PF10143 2,3-bisphosphoglycerate-independent phosphoglycerate mutase 40 208 8.5E-55 T 31-10-2018 IPR004456 2,3-bisphosphoglycerate-independent phosphoglycerate mutase GO:0003824|GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TK0866 2b424791471c5eabd5f4cea50f466782 411 Gene3D G3DSA:3.40.720.10 7 397 8.3E-145 T 31-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 TK0866 2b424791471c5eabd5f4cea50f466782 411 Hamap MF_01402_A 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [apgM]. 4 402 45.995 T 31-10-2018 IPR023665 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, prokaryotes GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TK0866 2b424791471c5eabd5f4cea50f466782 411 PIRSF PIRSF006392 1 407 3.9E-158 T 31-10-2018 IPR004456 2,3-bisphosphoglycerate-independent phosphoglycerate mutase GO:0003824|GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TK0866 2b424791471c5eabd5f4cea50f466782 411 Gene3D G3DSA:3.30.70.2130 81 230 8.3E-145 T 31-10-2018 TK1311 2336139fe2d0c871dbe1e9b6c99d64ce 125 Hamap MF_00326 50S ribosomal protein L7Ae [rpl7ae]. 5 124 35.632 T 31-10-2018 IPR022481 Ribosomal protein L7Ae, archaea GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 TK1311 2336139fe2d0c871dbe1e9b6c99d64ce 125 PRINTS PR00884 Ribosomal protein HS6 signature 8 19 1.7E-31 T 31-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 TK1311 2336139fe2d0c871dbe1e9b6c99d64ce 125 PRINTS PR00884 Ribosomal protein HS6 signature 52 63 1.7E-31 T 31-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 TK1311 2336139fe2d0c871dbe1e9b6c99d64ce 125 PRINTS PR00884 Ribosomal protein HS6 signature 42 52 1.7E-31 T 31-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 TK1311 2336139fe2d0c871dbe1e9b6c99d64ce 125 PRINTS PR00884 Ribosomal protein HS6 signature 93 109 1.7E-31 T 31-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 TK1311 2336139fe2d0c871dbe1e9b6c99d64ce 125 PRINTS PR00884 Ribosomal protein HS6 signature 79 89 1.7E-31 T 31-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 TK1311 2336139fe2d0c871dbe1e9b6c99d64ce 125 SUPERFAMILY SSF55315 6 123 1.38E-40 T 31-10-2018 IPR029064 50S ribosomal protein L30e-like TK1311 2336139fe2d0c871dbe1e9b6c99d64ce 125 ProSitePatterns PS01082 Ribosomal protein L7Ae signature. 72 89 - T 31-10-2018 IPR004037 Ribosomal protein L7Ae conserved site GO:0042254|GO:1990904 Reactome: R-HSA-6791226 TK1311 2336139fe2d0c871dbe1e9b6c99d64ce 125 PRINTS PR00881 Ribosomal protein L7A/RS6 family signature 69 79 1.5E-22 T 31-10-2018 IPR018492 Ribosomal protein L7Ae/L8/Nhp2 family TK1311 2336139fe2d0c871dbe1e9b6c99d64ce 125 PRINTS PR00881 Ribosomal protein L7A/RS6 family signature 53 66 1.5E-22 T 31-10-2018 IPR018492 Ribosomal protein L7Ae/L8/Nhp2 family TK1311 2336139fe2d0c871dbe1e9b6c99d64ce 125 PRINTS PR00881 Ribosomal protein L7A/RS6 family signature 34 48 1.5E-22 T 31-10-2018 IPR018492 Ribosomal protein L7Ae/L8/Nhp2 family TK1311 2336139fe2d0c871dbe1e9b6c99d64ce 125 PRINTS PR00881 Ribosomal protein L7A/RS6 family signature 79 93 1.5E-22 T 31-10-2018 IPR018492 Ribosomal protein L7Ae/L8/Nhp2 family TK1311 2336139fe2d0c871dbe1e9b6c99d64ce 125 Gene3D G3DSA:3.30.1330.30 1 125 7.2E-44 T 31-10-2018 IPR029064 50S ribosomal protein L30e-like TK1311 2336139fe2d0c871dbe1e9b6c99d64ce 125 Pfam PF01248 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family 20 112 5.9E-33 T 31-10-2018 IPR004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45 TK1311 2336139fe2d0c871dbe1e9b6c99d64ce 125 TIGRFAM TIGR03677 eL8_ribo: ribosomal protein eL8 8 123 5.9E-58 T 31-10-2018 IPR022481 Ribosomal protein L7Ae, archaea GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 TK2082 282a3a87310ad5b10794cca5d83e6ff5 123 TIGRFAM TIGR01300 CPA3_mnhG_phaG: monovalent cation/proton antiporter, MnhG/PhaG subunit 11 114 6.5E-34 T 31-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 TK2082 282a3a87310ad5b10794cca5d83e6ff5 123 Pfam PF03334 Na+/H+ antiporter subunit 11 100 3.1E-23 T 31-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 TK1801 7963dd70e7f42f5326d46933a0452aea 319 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 234 298 8.9E-21 T 31-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TK1801 7963dd70e7f42f5326d46933a0452aea 319 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 232 318 4.2E-31 T 31-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TK1801 7963dd70e7f42f5326d46933a0452aea 319 Gene3D G3DSA:3.40.50.300 3 319 2.8E-102 T 31-10-2018 TK1801 7963dd70e7f42f5326d46933a0452aea 319 SUPERFAMILY SSF52540 33 313 4.21E-69 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK1801 7963dd70e7f42f5326d46933a0452aea 319 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TK1801 7963dd70e7f42f5326d46933a0452aea 319 SMART SM00382 34 240 1.0E-9 T 31-10-2018 IPR003593 AAA+ ATPase domain TK1801 7963dd70e7f42f5326d46933a0452aea 319 Pfam PF00005 ABC transporter 26 182 5.7E-28 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TK0264 4f7848bc3c567b403bb9b15192cdb0fd 271 SUPERFAMILY SSF54211 23 171 7.51E-23 T 31-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TK0264 4f7848bc3c567b403bb9b15192cdb0fd 271 Pfam PF00288 GHMP kinases N terminal domain 76 143 2.5E-13 T 31-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 TK0264 4f7848bc3c567b403bb9b15192cdb0fd 271 Gene3D G3DSA:3.30.230.10 2 155 3.9E-21 T 31-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TK0264 4f7848bc3c567b403bb9b15192cdb0fd 271 TIGRFAM TIGR01920 Shik_kin_archae: shikimate kinase 5 267 4.5E-89 T 31-10-2018 IPR010189 Shikimate kinase, archaea GO:0004765|GO:0005737|GO:0009073 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 TK0264 4f7848bc3c567b403bb9b15192cdb0fd 271 Hamap MF_00370 Shikimate kinase [aroK]. 1 271 102.255 T 31-10-2018 IPR010189 Shikimate kinase, archaea GO:0004765|GO:0005737|GO:0009073 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 TK0264 4f7848bc3c567b403bb9b15192cdb0fd 271 PIRSF PIRSF005758 1 271 6.2E-91 T 31-10-2018 IPR010189 Shikimate kinase, archaea GO:0004765|GO:0005737|GO:0009073 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 TK1260 5d5896e21da00c1e841ac25cd4ec391c 94 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 23 91 3.6E-14 T 31-10-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core TK1260 5d5896e21da00c1e841ac25cd4ec391c 94 SUPERFAMILY SSF101386 1 91 5.56E-21 T 31-10-2018 TK1260 5d5896e21da00c1e841ac25cd4ec391c 94 PIRSF PIRSF029904 1 94 1.3E-32 T 31-10-2018 IPR012359 NTP pyrophosphohydrolase MazG-related, YpjD TK1260 5d5896e21da00c1e841ac25cd4ec391c 94 Gene3D G3DSA:1.10.287.1080 1 94 5.7E-25 T 31-10-2018 TK0596 efb920737ce104f375065b93bb733753 278 SUPERFAMILY SSF101576 94 163 3.53E-5 T 31-10-2018 IPR036598 GOLD domain superfamily TK0955 b5e815ead7f6ed852cef135e94c5c32c 413 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 312 342 7.5E-5 T 31-10-2018 IPR001451 Hexapeptide repeat TK0955 b5e815ead7f6ed852cef135e94c5c32c 413 Gene3D G3DSA:3.90.550.10 1 237 1.4E-73 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TK0955 b5e815ead7f6ed852cef135e94c5c32c 413 SUPERFAMILY SSF53448 1 299 5.16E-74 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TK0955 b5e815ead7f6ed852cef135e94c5c32c 413 Gene3D G3DSA:2.160.10.10 238 372 3.2E-18 T 31-10-2018 TK0955 b5e815ead7f6ed852cef135e94c5c32c 413 Pfam PF00483 Nucleotidyl transferase 2 230 1.9E-46 T 31-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 TK1755 819cad0cdcd267e2252a8a36dd64dea6 326 SUPERFAMILY SSF53697 2 325 8.9E-63 T 31-10-2018 TK1755 819cad0cdcd267e2252a8a36dd64dea6 326 Gene3D G3DSA:3.40.50.10490 3 162 2.7E-39 T 31-10-2018 TK1755 819cad0cdcd267e2252a8a36dd64dea6 326 Pfam PF01380 SIS domain 191 272 1.0E-7 T 31-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 TK1755 819cad0cdcd267e2252a8a36dd64dea6 326 Pfam PF01380 SIS domain 36 154 3.2E-8 T 31-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 TK1755 819cad0cdcd267e2252a8a36dd64dea6 326 Gene3D G3DSA:3.40.50.10490 164 312 4.5E-46 T 31-10-2018 TK1631 1e435c91611fa6472e083815c1708da9 137 Gene3D G3DSA:3.30.110.150 53 137 7.2E-25 T 31-10-2018 IPR038594 SepF-like superfamily TK1631 1e435c91611fa6472e083815c1708da9 137 PIRSF PIRSF019313 1 137 3.4E-28 T 31-10-2018 IPR012426 Uncharacterised protein family SepF-related, archaea TK1631 1e435c91611fa6472e083815c1708da9 137 Pfam PF04472 Cell division protein SepF 63 135 4.7E-16 T 31-10-2018 IPR007561 Cell division protein SepF/SepF-related GO:0090529 TK1038 d719e26bf8fee2c20c51794ad5972a89 290 SUPERFAMILY SSF52540 92 253 2.62E-10 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK1038 d719e26bf8fee2c20c51794ad5972a89 290 Hamap MF_00769 2-phosphoglycerate kinase [pgk2]. 5 289 44.669 T 31-10-2018 IPR020872 2-phosphoglycerate kinase GO:0016774 TK1038 d719e26bf8fee2c20c51794ad5972a89 290 Pfam PF03477 ATP cone domain 13 86 7.2E-9 T 31-10-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 TK1038 d719e26bf8fee2c20c51794ad5972a89 290 Gene3D G3DSA:3.40.50.300 82 288 8.7E-7 T 31-10-2018 TK1007 ea6e1b63a1d154a90e82f290373ce66d 429 SUPERFAMILY SSF103473 39 419 1.57E-43 T 31-10-2018 IPR036259 MFS transporter superfamily TK1007 ea6e1b63a1d154a90e82f290373ce66d 429 Gene3D G3DSA:1.20.1250.20 32 418 1.8E-37 T 31-10-2018 TK1007 ea6e1b63a1d154a90e82f290373ce66d 429 Pfam PF07690 Major Facilitator Superfamily 41 385 1.0E-23 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TK0659 e583a412071ab24d68d3afebe6bcdedd 344 Pfam PF02653 Branched-chain amino acid transport system / permease component 53 326 4.2E-41 T 31-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TK2233 aee4b8b656aaa7e3b11a5235adba745e 121 Pfam PF04266 ASCH domain 11 102 1.0E-13 T 31-10-2018 IPR007374 ASCH domain TK2233 aee4b8b656aaa7e3b11a5235adba745e 121 SUPERFAMILY SSF88697 3 114 2.65E-31 T 31-10-2018 IPR015947 PUA-like superfamily TK2233 aee4b8b656aaa7e3b11a5235adba745e 121 Gene3D G3DSA:2.30.130.30 6 105 3.6E-35 T 31-10-2018 TK2233 aee4b8b656aaa7e3b11a5235adba745e 121 SMART SM01022 9 103 1.7E-9 T 31-10-2018 IPR007374 ASCH domain TK0943 5a14207a7e47b6e9e2a86d66e0fefb25 243 Gene3D G3DSA:3.30.1490.20 40 117 1.1E-92 T 31-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 TK0943 5a14207a7e47b6e9e2a86d66e0fefb25 243 Gene3D G3DSA:3.30.470.20 19 234 1.1E-92 T 31-10-2018 TK0943 5a14207a7e47b6e9e2a86d66e0fefb25 243 Pfam PF13549 ATP-grasp domain 14 234 3.9E-80 T 31-10-2018 TK0943 5a14207a7e47b6e9e2a86d66e0fefb25 243 SUPERFAMILY SSF56059 21 236 9.55E-46 T 31-10-2018 TK0756 3b10c5a31c5116c1081dc93fdcd7e7c4 166 Gene3D G3DSA:3.40.50.1010 14 158 1.1E-11 T 31-10-2018 TK0756 3b10c5a31c5116c1081dc93fdcd7e7c4 166 Pfam PF01936 NYN domain 25 156 6.0E-21 T 31-10-2018 IPR021139 NYN domain, limkain-b1-type TK0756 3b10c5a31c5116c1081dc93fdcd7e7c4 166 TIGRFAM TIGR00288 TIGR00288: TIGR00288 family protein 14 156 1.3E-63 T 31-10-2018 IPR002790 Conserved hypothetical protein CHP00288 TK0756 3b10c5a31c5116c1081dc93fdcd7e7c4 166 ProDom PD010896 FAMILY DUF88 ARCHAEBACTERIAL PROTEIN MJ0482 PH0073 PF2040 VNG1608C MA3857 PF2039 24 97 4.0E-34 T 31-10-2018 TK0756 3b10c5a31c5116c1081dc93fdcd7e7c4 166 SUPERFAMILY SSF53822 69 152 2.59E-5 T 31-10-2018 IPR028082 Periplasmic binding protein-like I TK0799 1c9c13b34fda3aede92577c73042b827 567 Gene3D G3DSA:3.30.565.10 1 232 6.1E-66 T 31-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TK0799 1c9c13b34fda3aede92577c73042b827 567 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 32 131 2.6E-11 T 31-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TK0799 1c9c13b34fda3aede92577c73042b827 567 Pfam PF09239 Topoisomerase VI B subunit, transducer 354 509 1.2E-57 T 31-10-2018 IPR015320 DNA topoisomerase VI, subunit B, transducer GO:0003677|GO:0003918|GO:0006265 TK0799 1c9c13b34fda3aede92577c73042b827 567 Hamap MF_00322 Type 2 DNA topoisomerase 6 subunit B [top6B]. 8 550 31.615 T 31-10-2018 IPR005734 DNA topoisomerase VI, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TK0799 1c9c13b34fda3aede92577c73042b827 567 ProDom PD013790 TOPOISOMERASE ISOMERASE SUBUNIT DNA B VI TYPE II NUCLEOTIDE-BINDING ATP-BINDING 353 550 9.0E-113 T 31-10-2018 IPR015320 DNA topoisomerase VI, subunit B, transducer GO:0003677|GO:0003918|GO:0006265 TK0799 1c9c13b34fda3aede92577c73042b827 567 SUPERFAMILY SSF55874 18 229 6.68E-26 T 31-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TK0799 1c9c13b34fda3aede92577c73042b827 567 Gene3D G3DSA:3.30.230.10 353 567 3.0E-74 T 31-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TK0799 1c9c13b34fda3aede92577c73042b827 567 TIGRFAM TIGR01052 top6b: DNA topoisomerase VI, B subunit 10 534 3.7E-228 T 31-10-2018 IPR005734 DNA topoisomerase VI, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TK0799 1c9c13b34fda3aede92577c73042b827 567 Gene3D G3DSA:1.10.8.50 233 312 1.9E-8 T 31-10-2018 TK0799 1c9c13b34fda3aede92577c73042b827 567 PIRSF PIRSF006553 1 567 3.9E-212 T 31-10-2018 IPR005734 DNA topoisomerase VI, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TK0799 1c9c13b34fda3aede92577c73042b827 567 SMART SM00387 31 182 1.5E-8 T 31-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TK0799 1c9c13b34fda3aede92577c73042b827 567 SUPERFAMILY SSF54211 353 514 9.1E-62 T 31-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TK0655 a0c21ffe54d11078a5745c9e7fea2f7b 209 Pfam PF12728 Helix-turn-helix domain 7 54 2.8E-12 T 31-10-2018 TK0655 a0c21ffe54d11078a5745c9e7fea2f7b 209 Pfam PF00239 Resolvase, N terminal domain 63 198 1.9E-26 T 31-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 TK0655 a0c21ffe54d11078a5745c9e7fea2f7b 209 SUPERFAMILY SSF53041 63 194 3.14E-23 T 31-10-2018 IPR036162 Resolvase-like, N-terminal catalytic domain superfamily GO:0000150|GO:0003677|GO:0006310 TK0655 a0c21ffe54d11078a5745c9e7fea2f7b 209 ProSitePatterns PS00397 Site-specific recombinases active site. 66 74 - T 31-10-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 TK0655 a0c21ffe54d11078a5745c9e7fea2f7b 209 SUPERFAMILY SSF46955 6 56 6.87E-12 T 31-10-2018 IPR009061 Putative DNA-binding domain superfamily TK0655 a0c21ffe54d11078a5745c9e7fea2f7b 209 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 7 53 2.2E-11 T 31-10-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 TK0655 a0c21ffe54d11078a5745c9e7fea2f7b 209 SMART SM00857 63 202 7.5E-27 T 31-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 TK0655 a0c21ffe54d11078a5745c9e7fea2f7b 209 Gene3D G3DSA:3.40.50.1390 64 160 3.2E-28 T 31-10-2018 TK0655 a0c21ffe54d11078a5745c9e7fea2f7b 209 Gene3D G3DSA:1.10.1660.10 8 63 6.5E-14 T 31-10-2018 TK0677 bdbac57ee61f5b594a400ad6b379a1f2 290 Hamap MF_00188 Protease HtpX [htpX]. 6 282 30.215 T 31-10-2018 IPR022919 Peptidase M48, protease HtpX, putative GO:0004222 TK0677 bdbac57ee61f5b594a400ad6b379a1f2 290 Pfam PF01435 Peptidase family M48 68 282 8.6E-37 T 31-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 TK0677 bdbac57ee61f5b594a400ad6b379a1f2 290 Gene3D G3DSA:3.30.2010.10 62 151 7.2E-33 T 31-10-2018 TK1525 e25f7a5974412a8546e07a8bab3679d4 184 Gene3D G3DSA:3.90.930.12 7 85 3.2E-32 T 31-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1525 e25f7a5974412a8546e07a8bab3679d4 184 PIRSF PIRSF002162 5 182 1.5E-41 T 31-10-2018 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1525 e25f7a5974412a8546e07a8bab3679d4 184 TIGRFAM TIGR03653 uL6_arch: ribosomal protein uL6 8 177 3.6E-81 T 31-10-2018 IPR019907 Ribosomal protein L6P, archaea GO:0003735|GO:0005840|GO:0006412|GO:0019843 TK1525 e25f7a5974412a8546e07a8bab3679d4 184 ProSitePatterns PS00700 Ribosomal protein L6 signature 2. 156 177 - T 31-10-2018 IPR002359 Ribosomal protein L6, conserved site-2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1525 e25f7a5974412a8546e07a8bab3679d4 184 Gene3D G3DSA:3.90.930.12 86 182 3.2E-38 T 31-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1525 e25f7a5974412a8546e07a8bab3679d4 184 Hamap MF_01365_A 50S ribosomal protein L6 [rplF]. 2 178 39.939 T 31-10-2018 IPR019907 Ribosomal protein L6P, archaea GO:0003735|GO:0005840|GO:0006412|GO:0019843 TK1525 e25f7a5974412a8546e07a8bab3679d4 184 SUPERFAMILY SSF56053 86 177 5.1E-31 T 31-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1525 e25f7a5974412a8546e07a8bab3679d4 184 SUPERFAMILY SSF56053 8 85 9.87E-24 T 31-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1525 e25f7a5974412a8546e07a8bab3679d4 184 Pfam PF00347 Ribosomal protein L6 13 85 1.3E-19 T 31-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1525 e25f7a5974412a8546e07a8bab3679d4 184 Pfam PF00347 Ribosomal protein L6 97 171 2.3E-16 T 31-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK0710 cfae683bbdae46c62f0a1321fb06198e 245 SUPERFAMILY SSF159713 3 242 1.96E-57 T 31-10-2018 TK0710 cfae683bbdae46c62f0a1321fb06198e 245 Gene3D G3DSA:3.30.390.100 29 216 1.6E-23 T 31-10-2018 TK0710 cfae683bbdae46c62f0a1321fb06198e 245 Pfam PF13938 Putative heavy-metal chelation 10 89 1.1E-11 T 31-10-2018 IPR025251 Domain of unknown function DUF4213 TK0710 cfae683bbdae46c62f0a1321fb06198e 245 Gene3D G3DSA:3.40.50.11590 99 215 1.6E-23 T 31-10-2018 TK0710 cfae683bbdae46c62f0a1321fb06198e 245 Pfam PF04016 Putative heavy-metal chelation 107 241 2.1E-35 T 31-10-2018 IPR007161 Putative heavy-metal chelation domain TK0136 366d5ac1e161d2961ac86b3ab8d4f201 647 Pfam PF12838 4Fe-4S dicluster domain 593 639 1.6E-7 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TK0136 366d5ac1e161d2961ac86b3ab8d4f201 647 SUPERFAMILY SSF52518 14 250 1.77E-57 T 31-10-2018 IPR029061 Thiamin diphosphate-binding fold TK0136 366d5ac1e161d2961ac86b3ab8d4f201 647 PIRSF PIRSF006439 5 647 4.9E-258 T 31-10-2018 IPR017721 Indolepyruvate ferredoxin oxidoreductase, alpha subunit GO:0043805|GO:0055114 TK0136 366d5ac1e161d2961ac86b3ab8d4f201 647 SUPERFAMILY SSF52518 380 602 2.21E-29 T 31-10-2018 IPR029061 Thiamin diphosphate-binding fold TK0136 366d5ac1e161d2961ac86b3ab8d4f201 647 Gene3D G3DSA:3.40.50.970 389 580 8.6E-22 T 31-10-2018 TK0136 366d5ac1e161d2961ac86b3ab8d4f201 647 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 625 636 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TK0136 366d5ac1e161d2961ac86b3ab8d4f201 647 SUPERFAMILY SSF52922 248 355 5.89E-7 T 31-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TK0136 366d5ac1e161d2961ac86b3ab8d4f201 647 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 28 206 9.0E-15 T 31-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 TK0136 366d5ac1e161d2961ac86b3ab8d4f201 647 TIGRFAM TIGR03336 IOR_alpha: indolepyruvate ferredoxin oxidoreductase, alpha subunit 16 640 4.2E-270 T 31-10-2018 IPR017721 Indolepyruvate ferredoxin oxidoreductase, alpha subunit GO:0043805|GO:0055114 TK0136 366d5ac1e161d2961ac86b3ab8d4f201 647 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 410 564 1.5E-28 T 31-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 TK0136 366d5ac1e161d2961ac86b3ab8d4f201 647 SUPERFAMILY SSF54862 583 640 9.56E-15 T 31-10-2018 TK0136 366d5ac1e161d2961ac86b3ab8d4f201 647 Gene3D G3DSA:3.30.70.20 582 642 7.1E-11 T 31-10-2018 TK0136 366d5ac1e161d2961ac86b3ab8d4f201 647 Gene3D G3DSA:3.40.50.970 7 196 2.4E-53 T 31-10-2018 TK0459 a0c0c54d80c93ef6ec01604a02bbcd46 369 SUPERFAMILY SSF52540 3 282 4.82E-42 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK0459 a0c0c54d80c93ef6ec01604a02bbcd46 369 Gene3D G3DSA:3.40.50.300 7 209 4.0E-41 T 31-10-2018 TK0459 a0c0c54d80c93ef6ec01604a02bbcd46 369 Pfam PF01637 ATPase domain predominantly from Archaea 16 251 2.5E-15 T 31-10-2018 IPR011579 ATPase domain GO:0005524 TK0544 e62680995f19617b9f428e1da4b7ea8d 170 SMART SM00852 17 164 1.9E-26 T 31-10-2018 IPR001453 MoaB/Mog domain TK0544 e62680995f19617b9f428e1da4b7ea8d 170 Pfam PF00994 Probable molybdopterin binding domain 17 158 4.3E-33 T 31-10-2018 IPR001453 MoaB/Mog domain TK0544 e62680995f19617b9f428e1da4b7ea8d 170 Gene3D G3DSA:3.40.980.10 12 169 1.5E-43 T 31-10-2018 IPR036425 MoaB/Mog-like domain superfamily TK0544 e62680995f19617b9f428e1da4b7ea8d 170 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 14 158 2.8E-33 T 31-10-2018 IPR001453 MoaB/Mog domain TK0544 e62680995f19617b9f428e1da4b7ea8d 170 SUPERFAMILY SSF53218 12 167 1.23E-39 T 31-10-2018 IPR036425 MoaB/Mog-like domain superfamily TK0544 e62680995f19617b9f428e1da4b7ea8d 170 PIRSF PIRSF006443 1 170 3.7E-54 T 31-10-2018 IPR012245 Molybdenum cofactor biosynthesis protein MoaB GO:0006777 TK0240 81af9be725a9212dbf21a1a028a4ac76 273 SUPERFAMILY SSF52768 8 272 8.46E-76 T 31-10-2018 IPR023696 Ureohydrolase domain superfamily TK0240 81af9be725a9212dbf21a1a028a4ac76 273 ProSitePatterns PS01053 Arginase family signature. 203 224 - T 31-10-2018 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 TK0240 81af9be725a9212dbf21a1a028a4ac76 273 Pfam PF00491 Arginase family 13 271 3.5E-72 T 31-10-2018 IPR006035 Ureohydrolase GO:0046872 TK0240 81af9be725a9212dbf21a1a028a4ac76 273 TIGRFAM TIGR01230 agmatinase: agmatinase 8 271 2.1E-64 T 31-10-2018 IPR005925 Agmatinase-related KEGG: 00330+3.5.3.11|MetaCyc: PWY-40|MetaCyc: PWY-6305|Reactome: R-HSA-351143 TK0240 81af9be725a9212dbf21a1a028a4ac76 273 PIRSF PIRSF036979 5 273 9.9E-73 T 31-10-2018 IPR006035 Ureohydrolase GO:0046872 TK0240 81af9be725a9212dbf21a1a028a4ac76 273 Gene3D G3DSA:3.40.800.10 3 273 2.8E-79 T 31-10-2018 TK0450 18665dae31360f23e2142d3aeeecb952 533 Gene3D G3DSA:3.40.50.300 254 400 9.6E-14 T 31-10-2018 TK0450 18665dae31360f23e2142d3aeeecb952 533 Pfam PF00271 Helicase conserved C-terminal domain 258 361 2.7E-10 T 31-10-2018 IPR001650 Helicase, C-terminal TK0450 18665dae31360f23e2142d3aeeecb952 533 Gene3D G3DSA:3.40.50.300 26 225 6.1E-14 T 31-10-2018 TK0450 18665dae31360f23e2142d3aeeecb952 533 Pfam PF00270 DEAD/DEAH box helicase 50 206 3.1E-9 T 31-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 TK0450 18665dae31360f23e2142d3aeeecb952 533 SUPERFAMILY SSF52540 46 371 1.75E-30 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK0450 18665dae31360f23e2142d3aeeecb952 533 SMART SM00487 25 239 5.8E-11 T 31-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TK0450 18665dae31360f23e2142d3aeeecb952 533 SMART SM00490 271 361 1.1E-10 T 31-10-2018 IPR001650 Helicase, C-terminal TK0450 18665dae31360f23e2142d3aeeecb952 533 TIGRFAM TIGR01587 cas3_core: CRISPR-associated helicase Cas3 49 393 1.6E-91 T 31-10-2018 IPR006474 Helicase Cas3, CRISPR-associated, core TK0760 cc29f2f3b30f2c664f893e9d3474e9bb 580 Pfam PF14810 Patch-forming domain C2 of tRNA-guanine transglycosylase 436 503 1.7E-23 T 31-10-2018 IPR029402 tRNA-guanine transglycosylase, patch-forming domain C2 MetaCyc: PWY-6711|MetaCyc: PWY-7923 TK0760 cc29f2f3b30f2c664f893e9d3474e9bb 580 Gene3D G3DSA:2.30.130.10 502 579 6.6E-32 T 31-10-2018 IPR036974 PUA domain superfamily GO:0003723 TK0760 cc29f2f3b30f2c664f893e9d3474e9bb 580 Gene3D G3DSA:3.20.20.105 2 356 1.1E-125 T 31-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 TK0760 cc29f2f3b30f2c664f893e9d3474e9bb 580 TIGRFAM TIGR00432 arcsn_tRNA_tgt: tRNA-guanine(15) transglycosylase 6 388 3.2E-170 T 31-10-2018 IPR004804 tRNA-guanine(15) transglycosylase GO:0006400|GO:0016763 MetaCyc: PWY-6711|MetaCyc: PWY-7923 TK0760 cc29f2f3b30f2c664f893e9d3474e9bb 580 SUPERFAMILY SSF51713 4 354 1.44E-116 T 31-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 TK0760 cc29f2f3b30f2c664f893e9d3474e9bb 580 Gene3D G3DSA:3.10.450.90 427 501 4.3E-28 T 31-10-2018 IPR038250 TGT, patch-forming C2 domain superfamily MetaCyc: PWY-6711|MetaCyc: PWY-7923 TK0760 cc29f2f3b30f2c664f893e9d3474e9bb 580 TIGRFAM TIGR00451 unchar_dom_2: uncharacterized domain 2 485 575 3.3E-10 T 31-10-2018 IPR004521 Uncharacterised domain CHP00451 GO:0003723 TK0760 cc29f2f3b30f2c664f893e9d3474e9bb 580 Hamap MF_01634 tRNA-guanine(15) transglycosylase [tgtA]. 6 531 48.733 T 31-10-2018 IPR004804 tRNA-guanine(15) transglycosylase GO:0006400|GO:0016763 MetaCyc: PWY-6711|MetaCyc: PWY-7923 TK0760 cc29f2f3b30f2c664f893e9d3474e9bb 580 Pfam PF01702 Queuine tRNA-ribosyltransferase 109 330 4.9E-42 T 31-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 TK0760 cc29f2f3b30f2c664f893e9d3474e9bb 580 Gene3D G3DSA:3.90.1020.10 357 426 4.2E-28 T 31-10-2018 IPR038370 TGT, C1 domain superfamily MetaCyc: PWY-6711|MetaCyc: PWY-7923 TK0760 cc29f2f3b30f2c664f893e9d3474e9bb 580 SUPERFAMILY SSF88697 504 578 3.15E-20 T 31-10-2018 IPR015947 PUA-like superfamily TK0760 cc29f2f3b30f2c664f893e9d3474e9bb 580 SUPERFAMILY SSF88802 357 502 3.01E-42 T 31-10-2018 TK0760 cc29f2f3b30f2c664f893e9d3474e9bb 580 Pfam PF01472 PUA domain 506 577 2.2E-16 T 31-10-2018 IPR002478 PUA domain GO:0003723 TK0760 cc29f2f3b30f2c664f893e9d3474e9bb 580 TIGRFAM TIGR00449 tgt_general: tRNA-guanine family transglycosylase 6 337 1.6E-89 T 31-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 TK0760 cc29f2f3b30f2c664f893e9d3474e9bb 580 SMART SM00359 505 579 4.6E-20 T 31-10-2018 IPR002478 PUA domain GO:0003723 TK0760 cc29f2f3b30f2c664f893e9d3474e9bb 580 Pfam PF14809 C1 domain of tRNA-guanine transglycosylase dimerisation 357 426 1.3E-45 T 31-10-2018 IPR032729 tRNA-guanine(15) transglycosylase, C1 domain MetaCyc: PWY-6711|MetaCyc: PWY-7923 TK2158 cdb99e27ccad25c2ca7e0c8f83638710 315 Pfam PF00696 Amino acid kinase family 2 296 9.8E-30 T 31-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 TK2158 cdb99e27ccad25c2ca7e0c8f83638710 315 TIGRFAM TIGR00746 arcC: carbamate kinase 2 313 2.0E-145 T 31-10-2018 IPR003964 Carbamate kinase GO:0006525|GO:0008804 KEGG: 00220+2.7.2.2|KEGG: 00230+2.7.2.2|KEGG: 00910+2.7.2.2 TK2158 cdb99e27ccad25c2ca7e0c8f83638710 315 SUPERFAMILY SSF53633 1 313 4.19E-88 T 31-10-2018 IPR036393 Acetylglutamate kinase-like superfamily TK2158 cdb99e27ccad25c2ca7e0c8f83638710 315 PRINTS PR01469 Bacterial carbamate kinase signature 77 95 4.1E-67 T 31-10-2018 TK2158 cdb99e27ccad25c2ca7e0c8f83638710 315 PRINTS PR01469 Bacterial carbamate kinase signature 184 202 4.1E-67 T 31-10-2018 TK2158 cdb99e27ccad25c2ca7e0c8f83638710 315 PRINTS PR01469 Bacterial carbamate kinase signature 44 63 4.1E-67 T 31-10-2018 TK2158 cdb99e27ccad25c2ca7e0c8f83638710 315 PRINTS PR01469 Bacterial carbamate kinase signature 112 131 4.1E-67 T 31-10-2018 TK2158 cdb99e27ccad25c2ca7e0c8f83638710 315 PRINTS PR01469 Bacterial carbamate kinase signature 161 180 4.1E-67 T 31-10-2018 TK2158 cdb99e27ccad25c2ca7e0c8f83638710 315 PRINTS PR01469 Bacterial carbamate kinase signature 269 284 4.1E-67 T 31-10-2018 TK2158 cdb99e27ccad25c2ca7e0c8f83638710 315 PRINTS PR01469 Bacterial carbamate kinase signature 214 229 4.1E-67 T 31-10-2018 TK2158 cdb99e27ccad25c2ca7e0c8f83638710 315 PIRSF PIRSF000723 1 314 1.3E-140 T 31-10-2018 IPR003964 Carbamate kinase GO:0006525|GO:0008804 KEGG: 00220+2.7.2.2|KEGG: 00230+2.7.2.2|KEGG: 00910+2.7.2.2 TK2158 cdb99e27ccad25c2ca7e0c8f83638710 315 Gene3D G3DSA:3.40.1160.10 1 315 4.7E-136 T 31-10-2018 IPR036393 Acetylglutamate kinase-like superfamily TK1460 65a132d12a3ce5fa11e3183e4791dcbe 1282 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 688 712 2.3E-15 T 31-10-2018 TK1460 65a132d12a3ce5fa11e3183e4791dcbe 1282 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 370 386 2.3E-15 T 31-10-2018 TK1460 65a132d12a3ce5fa11e3183e4791dcbe 1282 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 422 436 2.3E-15 T 31-10-2018 TK1460 65a132d12a3ce5fa11e3183e4791dcbe 1282 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 650 662 2.3E-15 T 31-10-2018 TK1460 65a132d12a3ce5fa11e3183e4791dcbe 1282 Pfam PF02384 N-6 DNA Methylase 350 443 2.6E-5 T 31-10-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 TK1460 65a132d12a3ce5fa11e3183e4791dcbe 1282 Pfam PF12950 TaqI-like C-terminal specificity domain 880 1058 3.4E-9 T 31-10-2018 IPR025931 TaqI-like C-terminal specificity domain TK1460 65a132d12a3ce5fa11e3183e4791dcbe 1282 Pfam PF07669 Eco57I restriction-modification methylase 650 763 1.1E-13 T 31-10-2018 IPR011639 Restriction modification methylase Eco57I GO:0003677|GO:0003824|GO:0006304 TK1460 65a132d12a3ce5fa11e3183e4791dcbe 1282 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 653 659 - T 31-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 TK1460 65a132d12a3ce5fa11e3183e4791dcbe 1282 SUPERFAMILY SSF53335 211 767 3.02E-59 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TK1976 694b072caa0e7fffaa8079f5bd434b8e 442 Gene3D G3DSA:3.40.50.300 187 362 1.0E-42 T 31-10-2018 TK1976 694b072caa0e7fffaa8079f5bd434b8e 442 SUPERFAMILY SSF52540 188 404 1.52E-38 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK1976 694b072caa0e7fffaa8079f5bd434b8e 442 PIRSF PIRSF006809 1 422 1.5E-124 T 31-10-2018 IPR016496 GTPase HflX GO:0005525 TK1976 694b072caa0e7fffaa8079f5bd434b8e 442 Gene3D G3DSA:3.40.50.11060 8 129 1.5E-33 T 31-10-2018 TK1976 694b072caa0e7fffaa8079f5bd434b8e 442 Hamap MF_00900 GTPase HflX [hflX]. 17 391 43.448 T 31-10-2018 IPR016496 GTPase HflX GO:0005525 TK1976 694b072caa0e7fffaa8079f5bd434b8e 442 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 188 325 3.3E-12 T 31-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 TK1976 694b072caa0e7fffaa8079f5bd434b8e 442 Pfam PF01926 50S ribosome-binding GTPase 188 307 9.4E-20 T 31-10-2018 IPR006073 GTP binding domain GO:0005525 TK1976 694b072caa0e7fffaa8079f5bd434b8e 442 Pfam PF16360 GTP-binding GTPase Middle Region 103 180 1.6E-18 T 31-10-2018 IPR032305 GTP-binding protein, middle domain TK1976 694b072caa0e7fffaa8079f5bd434b8e 442 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 209 227 4.9E-7 T 31-10-2018 IPR006073 GTP binding domain GO:0005525 TK1976 694b072caa0e7fffaa8079f5bd434b8e 442 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 254 272 4.9E-7 T 31-10-2018 IPR006073 GTP binding domain GO:0005525 TK1976 694b072caa0e7fffaa8079f5bd434b8e 442 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 188 208 4.9E-7 T 31-10-2018 IPR006073 GTP binding domain GO:0005525 TK1976 694b072caa0e7fffaa8079f5bd434b8e 442 Pfam PF13167 GTP-binding GTPase N-terminal 18 100 2.9E-23 T 31-10-2018 IPR025121 GTPase HflX, N-terminal TK1976 694b072caa0e7fffaa8079f5bd434b8e 442 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 10 356 1.3E-93 T 31-10-2018 IPR016496 GTPase HflX GO:0005525 TK1982 85e76bfdba18813e8d25a4d54ade1b94 105 TIGRFAM TIGR02179 PorD_KorD: 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate family 29 104 3.7E-34 T 31-10-2018 IPR011898 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate GO:0016625|GO:0051539 TK1982 85e76bfdba18813e8d25a4d54ade1b94 105 SUPERFAMILY SSF54862 26 103 5.59E-24 T 31-10-2018 TK1982 85e76bfdba18813e8d25a4d54ade1b94 105 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 83 94 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TK1982 85e76bfdba18813e8d25a4d54ade1b94 105 Pfam PF14697 4Fe-4S dicluster domain 48 100 8.5E-11 T 31-10-2018 TK1982 85e76bfdba18813e8d25a4d54ade1b94 105 Gene3D G3DSA:3.30.70.20 7 105 5.7E-16 T 31-10-2018 TK2079 b97eb8649394051737585ec90330af13 342 Pfam PF01226 Formate/nitrite transporter 15 268 5.4E-72 T 31-10-2018 IPR000292 Formate/nitrite transporter GO:0016020|GO:0022857|GO:0055085 TK2079 b97eb8649394051737585ec90330af13 342 Gene3D G3DSA:1.20.1080.10 11 280 1.1E-76 T 31-10-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 TK1935 00f6d7855e0986326be31835cd611a2f 450 Pfam PF17125 N-terminal domain of 16S rRNA methyltransferase RsmF 152 205 5.1E-9 T 31-10-2018 IPR031341 Ribosomal RNA small subunit methyltransferase F, N-terminal Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 TK1935 00f6d7855e0986326be31835cd611a2f 450 Gene3D G3DSA:3.40.50.150 149 439 5.2E-92 T 31-10-2018 TK1935 00f6d7855e0986326be31835cd611a2f 450 TIGRFAM TIGR00446 nop2p: NOL1/NOP2/sun family putative RNA methylase 182 439 4.2E-65 T 31-10-2018 IPR011023 Nop2p GO:0003723|GO:0006364|GO:0008757 Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 TK1935 00f6d7855e0986326be31835cd611a2f 450 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 226 240 5.1E-24 T 31-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TK1935 00f6d7855e0986326be31835cd611a2f 450 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 323 335 5.1E-24 T 31-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TK1935 00f6d7855e0986326be31835cd611a2f 450 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 422 439 5.1E-24 T 31-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TK1935 00f6d7855e0986326be31835cd611a2f 450 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 255 265 5.1E-24 T 31-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TK1935 00f6d7855e0986326be31835cd611a2f 450 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 373 389 5.1E-24 T 31-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TK1935 00f6d7855e0986326be31835cd611a2f 450 Gene3D G3DSA:1.10.940.10 2 148 1.0E-41 T 31-10-2018 IPR035926 NusB-like superfamily TK1935 00f6d7855e0986326be31835cd611a2f 450 SUPERFAMILY SSF53335 144 439 2.3E-78 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TK1935 00f6d7855e0986326be31835cd611a2f 450 Pfam PF01189 16S rRNA methyltransferase RsmB/F 244 437 8.3E-65 T 31-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 TK0861 4b7eec5b872808bb4079436c5a8ebde0 193 SUPERFAMILY SSF52402 2 188 1.13E-42 T 31-10-2018 TK0861 4b7eec5b872808bb4079436c5a8ebde0 193 Gene3D G3DSA:3.40.50.620 2 131 2.7E-19 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TK0861 4b7eec5b872808bb4079436c5a8ebde0 193 Pfam PF01902 Diphthamide synthase 2 177 2.6E-27 T 31-10-2018 IPR002761 Diphthamide synthase domain MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 TK2071 46aa5928b2939ed4735c62e7bbfd8e07 294 Gene3D G3DSA:2.10.240.10 251 286 1.8E-7 T 31-10-2018 IPR037117 Dihydroorotate dehydrogenase, electron transfer subunit, Fe-S binding domain superfamily TK2071 46aa5928b2939ed4735c62e7bbfd8e07 294 Gene3D G3DSA:2.40.30.10 16 114 3.6E-19 T 31-10-2018 TK2071 46aa5928b2939ed4735c62e7bbfd8e07 294 PRINTS PR00410 Phenol hydroxylase reductase family signature 218 226 1.4E-7 T 31-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 TK2071 46aa5928b2939ed4735c62e7bbfd8e07 294 PRINTS PR00410 Phenol hydroxylase reductase family signature 52 64 1.4E-7 T 31-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 TK2071 46aa5928b2939ed4735c62e7bbfd8e07 294 PRINTS PR00410 Phenol hydroxylase reductase family signature 126 145 1.4E-7 T 31-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 TK2071 46aa5928b2939ed4735c62e7bbfd8e07 294 Gene3D G3DSA:3.40.50.80 119 250 5.5E-22 T 31-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain TK2071 46aa5928b2939ed4735c62e7bbfd8e07 294 PIRSF PIRSF006816 16 293 8.9E-83 T 31-10-2018 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 TK2071 46aa5928b2939ed4735c62e7bbfd8e07 294 SUPERFAMILY SSF63380 13 118 2.69E-23 T 31-10-2018 IPR017938 Riboflavin synthase-like beta-barrel TK2071 46aa5928b2939ed4735c62e7bbfd8e07 294 SUPERFAMILY SSF52343 110 285 7.2E-32 T 31-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain TK2071 46aa5928b2939ed4735c62e7bbfd8e07 294 Pfam PF00970 Oxidoreductase FAD-binding domain 37 113 2.0E-7 T 31-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 TK2071 46aa5928b2939ed4735c62e7bbfd8e07 294 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 250 285 1.1E-12 T 31-10-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain TK2071 46aa5928b2939ed4735c62e7bbfd8e07 294 Pfam PF00175 Oxidoreductase NAD-binding domain 127 231 3.5E-12 T 31-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 TK0699 917c01fa902035bd90ffbc3158f1f9d8 473 Pfam PF01523 Putative modulator of DNA gyrase 19 325 1.3E-54 T 31-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 TK0699 917c01fa902035bd90ffbc3158f1f9d8 473 Gene3D G3DSA:3.30.2290.10 1 196 8.3E-24 T 31-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal TK0699 917c01fa902035bd90ffbc3158f1f9d8 473 SUPERFAMILY SSF111283 1 468 6.28E-104 T 31-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 TK0699 917c01fa902035bd90ffbc3158f1f9d8 473 PIRSF PIRSF004919 1 472 1.3E-148 T 31-10-2018 IPR025502 TldD TK0357 accfcdca8b8ac837b50d268f7720ef04 308 Pfam PF12679 ABC-2 family transporter protein 5 307 7.5E-67 T 31-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 TK2298 1746988f4296e9f2102496ee71f376df 610 Pfam PF13597 Anaerobic ribonucleoside-triphosphate reductase 19 608 3.1E-151 T 31-10-2018 IPR012833 Ribonucleoside-triphosphate reductase, anaerobic GO:0006260|GO:0008998|GO:0016491|GO:0055114 KEGG: 00230+1.1.98.6|KEGG: 00240+1.1.98.6|MetaCyc: PWY-7187|MetaCyc: PWY-7220|MetaCyc: PWY-7222 TK2298 1746988f4296e9f2102496ee71f376df 610 Gene3D G3DSA:3.20.70.20 30 590 1.9E-69 T 31-10-2018 TK2298 1746988f4296e9f2102496ee71f376df 610 SUPERFAMILY SSF51998 20 592 3.97E-128 T 31-10-2018 TK2298 1746988f4296e9f2102496ee71f376df 610 TIGRFAM TIGR02487 NrdD: anaerobic ribonucleoside-triphosphate reductase 19 607 4.2E-158 T 31-10-2018 IPR012833 Ribonucleoside-triphosphate reductase, anaerobic GO:0006260|GO:0008998|GO:0016491|GO:0055114 KEGG: 00230+1.1.98.6|KEGG: 00240+1.1.98.6|MetaCyc: PWY-7187|MetaCyc: PWY-7220|MetaCyc: PWY-7222 TK0314 6166f4c614298e494630d35e7e5ec87c 240 Gene3D G3DSA:3.60.15.10 9 236 3.3E-48 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TK0314 6166f4c614298e494630d35e7e5ec87c 240 Pfam PF00753 Metallo-beta-lactamase superfamily 30 221 3.5E-24 T 31-10-2018 IPR001279 Metallo-beta-lactamase TK0314 6166f4c614298e494630d35e7e5ec87c 240 SUPERFAMILY SSF56281 16 239 5.37E-47 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TK0314 6166f4c614298e494630d35e7e5ec87c 240 SMART SM00849 31 221 2.3E-36 T 31-10-2018 IPR001279 Metallo-beta-lactamase TK0562 bed9683630c4944b73a41ae1ebbb9b9f 113 SUPERFAMILY SSF88659 46 93 6.54E-9 T 31-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like TK0562 bed9683630c4944b73a41ae1ebbb9b9f 113 Hamap MF_00674 UPF0251 protein . 12 109 24.099 T 31-10-2018 IPR002852 Uncharacterised protein family UPF0251 TK0562 bed9683630c4944b73a41ae1ebbb9b9f 113 Pfam PF02001 Protein of unknown function DUF134 11 105 2.5E-27 T 31-10-2018 IPR002852 Uncharacterised protein family UPF0251 TK0562 bed9683630c4944b73a41ae1ebbb9b9f 113 Gene3D G3DSA:1.10.10.10 45 94 2.3E-10 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TK2140 5f5d6877fcd236408cf45dc45586eedb 562 TIGRFAM TIGR00574 dnl1: DNA ligase I, ATP-dependent (dnl1) 60 553 1.2E-167 T 31-10-2018 IPR000977 DNA ligase, ATP-dependent GO:0003910|GO:0005524|GO:0006281|GO:0006310|GO:0071897 TK2140 5f5d6877fcd236408cf45dc45586eedb 562 Pfam PF04679 ATP dependent DNA ligase C terminal region 446 537 3.0E-21 T 31-10-2018 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 TK2140 5f5d6877fcd236408cf45dc45586eedb 562 SUPERFAMILY SSF117018 3 244 8.5E-72 T 31-10-2018 IPR036599 DNA ligase, ATP-dependent, N-terminal domain superfamily GO:0003677|GO:0003910|GO:0006281|GO:0006310 TK2140 5f5d6877fcd236408cf45dc45586eedb 562 Pfam PF01068 ATP dependent DNA ligase domain 227 425 1.5E-64 T 31-10-2018 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 TK2140 5f5d6877fcd236408cf45dc45586eedb 562 SUPERFAMILY SSF50249 429 555 6.85E-41 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold TK2140 5f5d6877fcd236408cf45dc45586eedb 562 ProSitePatterns PS00697 ATP-dependent DNA ligase AMP-binding site. 250 258 - T 31-10-2018 IPR016059 DNA ligase, ATP-dependent, conserved site GO:0003909|GO:0051103 TK2140 5f5d6877fcd236408cf45dc45586eedb 562 SUPERFAMILY SSF56091 222 425 3.6E-54 T 31-10-2018 TK2140 5f5d6877fcd236408cf45dc45586eedb 562 Pfam PF04675 DNA ligase N terminus 6 179 9.9E-40 T 31-10-2018 IPR012308 DNA ligase, ATP-dependent, N-terminal GO:0003677|GO:0003910|GO:0006281|GO:0006310 TK2140 5f5d6877fcd236408cf45dc45586eedb 562 Hamap MF_00407 DNA ligase [lig]. 4 553 34.296 T 31-10-2018 IPR022865 DNA ligase, ATP-dependent, bacterial/archaeal GO:0003910 TK2140 5f5d6877fcd236408cf45dc45586eedb 562 Gene3D G3DSA:2.40.50.140 426 562 7.0E-53 T 31-10-2018 TK2140 5f5d6877fcd236408cf45dc45586eedb 562 Gene3D G3DSA:3.30.470.30 224 425 5.6E-74 T 31-10-2018 TK2140 5f5d6877fcd236408cf45dc45586eedb 562 Gene3D G3DSA:1.10.3260.10 1 223 1.5E-86 T 31-10-2018 IPR036599 DNA ligase, ATP-dependent, N-terminal domain superfamily GO:0003677|GO:0003910|GO:0006281|GO:0006310 TK2140 5f5d6877fcd236408cf45dc45586eedb 562 ProSitePatterns PS00333 ATP-dependent DNA ligase signature 2. 401 425 - T 31-10-2018 IPR016059 DNA ligase, ATP-dependent, conserved site GO:0003909|GO:0051103 TK1467 8364d034fe794598cb8c52b6008d20df 214 Pfam PF11667 Putative zincin peptidase 56 157 2.8E-19 T 31-10-2018 IPR021683 Putative zincin peptidase TK2172 87acae0ddc30fbb1e5ff8793a675f256 713 SUPERFAMILY SSF51445 24 420 6.09E-81 T 31-10-2018 IPR017853 Glycoside hydrolase superfamily TK2172 87acae0ddc30fbb1e5ff8793a675f256 713 SMART SM00632 433 502 0.0036 T 31-10-2018 IPR031319 Alpha-amylase, C-terminal domain Reactome: R-HSA-189085 TK2172 87acae0ddc30fbb1e5ff8793a675f256 713 Gene3D G3DSA:3.20.20.80 22 416 6.7E-106 T 31-10-2018 TK2172 87acae0ddc30fbb1e5ff8793a675f256 713 SUPERFAMILY SSF81296 505 575 9.66E-13 T 31-10-2018 IPR014756 Immunoglobulin E-set TK2172 87acae0ddc30fbb1e5ff8793a675f256 713 SUPERFAMILY SSF51011 423 502 2.12E-15 T 31-10-2018 TK2172 87acae0ddc30fbb1e5ff8793a675f256 713 SMART SM00642 31 414 9.1E-82 T 31-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 TK2172 87acae0ddc30fbb1e5ff8793a675f256 713 Gene3D G3DSA:2.60.40.10 504 579 3.6E-14 T 31-10-2018 IPR013783 Immunoglobulin-like fold TK2172 87acae0ddc30fbb1e5ff8793a675f256 713 Pfam PF01833 IPT/TIG domain 506 584 2.5E-8 T 31-10-2018 IPR002909 IPT domain TK2172 87acae0ddc30fbb1e5ff8793a675f256 713 Pfam PF00128 Alpha amylase, catalytic domain 62 381 1.9E-53 T 31-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 TK2172 87acae0ddc30fbb1e5ff8793a675f256 713 Gene3D G3DSA:2.60.40.1180 417 500 3.3E-10 T 31-10-2018 IPR013780 Glycosyl hydrolase, all-beta TK2172 87acae0ddc30fbb1e5ff8793a675f256 713 Pfam PF02806 Alpha amylase, C-terminal all-beta domain 435 499 7.6E-7 T 31-10-2018 IPR006048 Alpha-amylase/branching enzyme, C-terminal all beta GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900 TK2159 54c80c7a1a77d13c029dab6a4bc41396 420 SUPERFAMILY SSF51905 3 319 2.59E-36 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TK2159 54c80c7a1a77d13c029dab6a4bc41396 420 Gene3D G3DSA:3.50.50.60 4 403 3.1E-140 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TK2159 54c80c7a1a77d13c029dab6a4bc41396 420 PRINTS PR00419 Adrenodoxin reductase family signature 25 38 7.3E-5 T 31-10-2018 TK2159 54c80c7a1a77d13c029dab6a4bc41396 420 PRINTS PR00419 Adrenodoxin reductase family signature 2 24 7.3E-5 T 31-10-2018 TK2159 54c80c7a1a77d13c029dab6a4bc41396 420 Gene3D G3DSA:3.90.660.50 83 359 3.1E-140 T 31-10-2018 TK2159 54c80c7a1a77d13c029dab6a4bc41396 420 Pfam PF13450 NAD(P)-binding Rossmann-like domain 5 69 1.7E-12 T 31-10-2018 TK1468 914d2dfe52258c98a52f6c341625cd80 343 SUPERFAMILY SSF48576 3 342 2.16E-96 T 31-10-2018 IPR008949 Isoprenoid synthase domain superfamily TK1468 914d2dfe52258c98a52f6c341625cd80 343 Pfam PF00348 Polyprenyl synthetase 34 270 7.7E-70 T 31-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 TK1468 914d2dfe52258c98a52f6c341625cd80 343 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 210 222 - T 31-10-2018 IPR033749 Polyprenyl synthetase, conserved site TK1468 914d2dfe52258c98a52f6c341625cd80 343 Gene3D G3DSA:1.10.600.10 1 343 2.5E-133 T 31-10-2018 IPR008949 Isoprenoid synthase domain superfamily TK1468 914d2dfe52258c98a52f6c341625cd80 343 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 83 97 - T 31-10-2018 IPR033749 Polyprenyl synthetase, conserved site TK1050 4d5b11f8de8dc7fc0b40906e925efcf2 320 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 255 310 3.1E-6 T 31-10-2018 IPR002831 Transcription regulator TrmB, N-terminal TK1050 4d5b11f8de8dc7fc0b40906e925efcf2 320 SUPERFAMILY SSF46785 246 318 1.6E-11 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TK1050 4d5b11f8de8dc7fc0b40906e925efcf2 320 Gene3D G3DSA:1.10.10.10 236 319 8.5E-10 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TK0740 bce253c7abb6be692050141a3ff25f75 95 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 24 35 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TK0740 bce253c7abb6be692050141a3ff25f75 95 Pfam PF12838 4Fe-4S dicluster domain 24 77 5.7E-9 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TK0740 bce253c7abb6be692050141a3ff25f75 95 SUPERFAMILY SSF54862 16 78 1.92E-12 T 31-10-2018 TK0740 bce253c7abb6be692050141a3ff25f75 95 Gene3D G3DSA:3.30.70.20 19 79 2.5E-9 T 31-10-2018 TK0335 9657d10b9df96cc9a96180efb7239371 67 SUPERFAMILY SSF141694 2 61 3.4E-15 T 31-10-2018 TK0335 9657d10b9df96cc9a96180efb7239371 67 Pfam PF01954 Protein of unknown function DUF104 3 52 2.3E-16 T 31-10-2018 IPR008203 Uncharacterised protein family UPF0165 TK0335 9657d10b9df96cc9a96180efb7239371 67 Gene3D G3DSA:4.10.1150.10 1 67 1.7E-11 T 31-10-2018 IPR024069 AF2212-like domain superfamily TK0267 43c3306d12a50f6d2ee68e775e7d884b 341 Hamap MF_00110 3-dehydroquinate synthase [aroB]. 1 328 55.808 T 31-10-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 TK0267 43c3306d12a50f6d2ee68e775e7d884b 341 TIGRFAM TIGR01357 aroB: 3-dehydroquinate synthase 15 320 3.3E-94 T 31-10-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 TK0267 43c3306d12a50f6d2ee68e775e7d884b 341 Pfam PF01761 3-dehydroquinate synthase 50 292 1.2E-80 T 31-10-2018 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 TK0267 43c3306d12a50f6d2ee68e775e7d884b 341 Gene3D G3DSA:3.40.50.1970 6 154 1.3E-48 T 31-10-2018 TK0267 43c3306d12a50f6d2ee68e775e7d884b 341 SUPERFAMILY SSF56796 11 325 7.98E-86 T 31-10-2018 TK0267 43c3306d12a50f6d2ee68e775e7d884b 341 PIRSF PIRSF001455 9 329 6.9E-95 T 31-10-2018 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 TK0267 43c3306d12a50f6d2ee68e775e7d884b 341 Gene3D G3DSA:1.20.1090.10 155 326 7.7E-46 T 31-10-2018 TK1502 375e886aa8e794177a90edb5b1d9f84f 121 ProSitePatterns PS01106 Ribosomal protein L18e signature. 36 53 - T 31-10-2018 IPR021132 Ribosomal protein L18e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1502 375e886aa8e794177a90edb5b1d9f84f 121 Hamap MF_00329 50S ribosomal protein L18e [rpl18e]. 5 121 30.821 T 31-10-2018 IPR022947 Ribosomal protein L18e, archaea TK1502 375e886aa8e794177a90edb5b1d9f84f 121 Pfam PF17135 Ribosomal protein 60S L18 and 50S L18e 12 120 4.3E-15 T 31-10-2018 IPR021131 Ribosomal protein L18e/L15P TK1502 375e886aa8e794177a90edb5b1d9f84f 121 SUPERFAMILY SSF52080 6 120 7.98E-30 T 31-10-2018 IPR036227 Ribosomal L18e/L15P superfamily TK1502 375e886aa8e794177a90edb5b1d9f84f 121 Gene3D G3DSA:3.100.10.10 6 121 3.0E-39 T 31-10-2018 TK1101 276585aa9969c8b61c04cb6c81a1d6ea 59 Hamap MF_00803 Ribosome biogenesis protein Nop10 [nop10]. 3 53 21.365 T 31-10-2018 IPR023532 H/ACA ribonucleoprotein complex subunit Nop10 , archaeal-type GO:0001522|GO:0030515|GO:0042254 TK1101 276585aa9969c8b61c04cb6c81a1d6ea 59 SUPERFAMILY SSF144210 4 51 2.49E-22 T 31-10-2018 IPR036756 H/ACA ribonucleoprotein complex, subunit Nop10 superfamily GO:0001522|GO:0030515|GO:0042254 Reactome: R-HSA-6790901 TK1101 276585aa9969c8b61c04cb6c81a1d6ea 59 Pfam PF04135 Nucleolar RNA-binding protein, Nop10p family 1 51 2.1E-28 T 31-10-2018 IPR007264 H/ACA ribonucleoprotein complex, subunit Nop10 GO:0001522|GO:0030515|GO:0042254 Reactome: R-HSA-6790901 TK1101 276585aa9969c8b61c04cb6c81a1d6ea 59 Gene3D G3DSA:2.20.28.40 1 59 4.0E-32 T 31-10-2018 IPR036756 H/ACA ribonucleoprotein complex, subunit Nop10 superfamily GO:0001522|GO:0030515|GO:0042254 Reactome: R-HSA-6790901 TK0414 fb992dde6dba7349246795797fc2d69d 63 SUPERFAMILY SSF46785 11 52 9.92E-5 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TK0414 fb992dde6dba7349246795797fc2d69d 63 Gene3D G3DSA:1.10.10.10 9 58 1.9E-5 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TK0962 4ed474167dca49fcc2880427c11cc501 104 Pfam PF01909 Nucleotidyltransferase domain 9 89 2.0E-12 T 31-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 TK0962 4ed474167dca49fcc2880427c11cc501 104 Gene3D G3DSA:3.30.460.10 1 102 1.0E-19 T 31-10-2018 TK0962 4ed474167dca49fcc2880427c11cc501 104 SUPERFAMILY SSF81301 2 102 5.79E-16 T 31-10-2018 TK1438 c3487e6ba7f967345f41d195ec3080e0 650 Pfam PF05670 Domain of unknown function (DUF814) 455 553 3.1E-26 T 31-10-2018 IPR008532 Domain of unknown function DUF814 TK1438 c3487e6ba7f967345f41d195ec3080e0 650 Gene3D G3DSA:2.30.310.10 5 150 2.9E-32 T 31-10-2018 TK1438 c3487e6ba7f967345f41d195ec3080e0 650 Pfam PF05833 Fibronectin-binding protein A N-terminus (FbpA) 7 435 1.1E-86 T 31-10-2018 TK0062 4ca04609c497207a0cf6106557d5c608 256 Gene3D G3DSA:3.40.50.10790 1 160 9.0E-61 T 31-10-2018 IPR023228 S-adenosyl-l-methionine hydroxide adenosyltransferase, N-terminal TK0062 4ca04609c497207a0cf6106557d5c608 256 SUPERFAMILY SSF101852 164 252 2.88E-25 T 31-10-2018 IPR023227 S-adenosyl-l-methionine hydroxide adenosyltransferase, C-terminal TK0062 4ca04609c497207a0cf6106557d5c608 256 PIRSF PIRSF006779 1 256 6.8E-76 T 31-10-2018 IPR002747 SAM-dependent chlorinase/fluorinase TK0062 4ca04609c497207a0cf6106557d5c608 256 Gene3D G3DSA:2.40.30.90 161 256 1.8E-34 T 31-10-2018 IPR023227 S-adenosyl-l-methionine hydroxide adenosyltransferase, C-terminal TK0062 4ca04609c497207a0cf6106557d5c608 256 SUPERFAMILY SSF102522 1 161 1.96E-55 T 31-10-2018 IPR023228 S-adenosyl-l-methionine hydroxide adenosyltransferase, N-terminal TK0062 4ca04609c497207a0cf6106557d5c608 256 Pfam PF01887 S-adenosyl-l-methionine hydroxide adenosyltransferase 2 252 5.3E-78 T 31-10-2018 IPR002747 SAM-dependent chlorinase/fluorinase TK1873 41f0abbde8fd5415342a1448a8c96ee3 618 Gene3D G3DSA:1.10.390.60 277 523 7.1E-20 T 31-10-2018 TK1873 41f0abbde8fd5415342a1448a8c96ee3 618 Pfam PF01433 Peptidase family M1 domain 369 519 9.0E-8 T 31-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 TK1873 41f0abbde8fd5415342a1448a8c96ee3 618 SUPERFAMILY SSF55486 279 530 1.2E-18 T 31-10-2018 TK0616 7152b53b0e8b1c83333fbaeee8863cf4 49 Pfam PF03604 DNA directed RNA polymerase, 7 kDa subunit 6 39 1.3E-10 T 31-10-2018 IPR006591 RNA polymerase archaeal subunit P/eukaryotic subunit RPABC4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 TK0616 7152b53b0e8b1c83333fbaeee8863cf4 49 Gene3D G3DSA:2.20.28.30 1 49 8.4E-25 T 31-10-2018 TK0616 7152b53b0e8b1c83333fbaeee8863cf4 49 Hamap MF_00615 DNA-directed RNA polymerase subunit P [rpoP]. 6 49 16.49 T 31-10-2018 IPR023464 DNA-directed RNA polymerase subunit P (Rpo12) GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TK0616 7152b53b0e8b1c83333fbaeee8863cf4 49 SUPERFAMILY SSF63393 4 48 1.05E-12 T 31-10-2018 IPR029040 RNA polymerase subunit RPABC4/transcription elongation factor Spt4 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-75955 TK0616 7152b53b0e8b1c83333fbaeee8863cf4 49 SMART SM00659 4 49 8.8E-20 T 31-10-2018 IPR006591 RNA polymerase archaeal subunit P/eukaryotic subunit RPABC4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 TK2040 48025bee0483fde6c1cdac6b116f5b81 310 ProSitePatterns PS00869 Renal dipeptidase active site. 99 121 - T 31-10-2018 IPR000180 Membrane dipeptidase, active site GO:0006508|GO:0008235|GO:0008239|GO:0016805 MetaCyc: PWY-7533|Reactome: R-HSA-2142691|Reactome: R-HSA-5423646 TK2040 48025bee0483fde6c1cdac6b116f5b81 310 Gene3D G3DSA:3.20.20.140 1 310 1.2E-94 T 31-10-2018 TK2040 48025bee0483fde6c1cdac6b116f5b81 310 Pfam PF01244 Membrane dipeptidase (Peptidase family M19) 2 307 6.0E-92 T 31-10-2018 IPR008257 Peptidase M19 GO:0006508|GO:0016805 MetaCyc: PWY-7533|Reactome: R-HSA-2142691|Reactome: R-HSA-5423646 TK2040 48025bee0483fde6c1cdac6b116f5b81 310 SUPERFAMILY SSF51556 1 309 5.25E-73 T 31-10-2018 IPR032466 Metal-dependent hydrolase TK1066 975e9511acf7b5ce3532ce7965f1ea0b 605 Gene3D G3DSA:3.60.9.10 1 211 4.9E-96 T 31-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily TK1066 975e9511acf7b5ce3532ce7965f1ea0b 605 Gene3D G3DSA:1.10.599.10 240 601 7.5E-159 T 31-10-2018 IPR013985 Aldehyde ferredoxin oxidoreductase, domain 3 GO:0016625|GO:0051536|GO:0055114 KEGG: 00030+1.2.7.5 TK1066 975e9511acf7b5ce3532ce7965f1ea0b 605 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 6 205 2.0E-83 T 31-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 TK1066 975e9511acf7b5ce3532ce7965f1ea0b 605 Gene3D G3DSA:1.10.569.10 242 427 7.5E-159 T 31-10-2018 IPR013984 Aldehyde ferredoxin oxidoreductase, domain 2 TK1066 975e9511acf7b5ce3532ce7965f1ea0b 605 SUPERFAMILY SSF56228 1 209 7.06E-79 T 31-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily TK1066 975e9511acf7b5ce3532ce7965f1ea0b 605 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 223 601 1.9E-143 T 31-10-2018 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 TK1066 975e9511acf7b5ce3532ce7965f1ea0b 605 SMART SM00790 4 207 4.5E-133 T 31-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 TK1066 975e9511acf7b5ce3532ce7965f1ea0b 605 SUPERFAMILY SSF48310 211 604 1.31E-147 T 31-10-2018 IPR036021 Aldehyde ferredoxin oxidoreductase-like, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 TK1809 a505ee51609c7675432c41d2ff37ff66 653 Gene3D G3DSA:2.70.98.10 388 653 1.5E-88 T 31-10-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 TK1809 a505ee51609c7675432c41d2ff37ff66 653 SUPERFAMILY SSF74650 387 652 1.07E-99 T 31-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 TK1809 a505ee51609c7675432c41d2ff37ff66 653 Pfam PF09094 Domain of unknown function (DUF1925) 311 382 1.5E-37 T 31-10-2018 IPR015178 Alpha-amylase/4-alpha-glucanotransferase, central domain TK1809 a505ee51609c7675432c41d2ff37ff66 653 SUPERFAMILY SSF88688 311 383 1.63E-37 T 31-10-2018 IPR028995 Glycoside hydrolase families 57/38, central domain superfamily TK1809 a505ee51609c7675432c41d2ff37ff66 653 ProDom PD014405 HYDROLASE METABOLISM CARBOHYDRATE GLYCOSIDASE ALPHA-AMYLASE TRANSFERASE 4-ALPHA-GLUCANOTRANSFERASE GLYCOSYLTRANSFERASE FAMILY DIRECT 319 384 2.0E-33 T 31-10-2018 IPR015178 Alpha-amylase/4-alpha-glucanotransferase, central domain TK1809 a505ee51609c7675432c41d2ff37ff66 653 Pfam PF03065 Glycosyl hydrolase family 57 7 290 1.7E-65 T 31-10-2018 IPR004300 Glycoside hydrolase family 57, N-terminal domain GO:0003824|GO:0005975 TK1809 a505ee51609c7675432c41d2ff37ff66 653 Pfam PF09095 Domain of unknown function (DUF1926) 392 648 4.1E-80 T 31-10-2018 IPR015179 Alpha-amylase/4-alpha-glucanotransferase, C-terminal GO:0003824|GO:0005975|GO:0030246 TK1809 a505ee51609c7675432c41d2ff37ff66 653 Gene3D G3DSA:3.20.110.20 1 381 1.3E-176 T 31-10-2018 TK1809 a505ee51609c7675432c41d2ff37ff66 653 SUPERFAMILY SSF88713 1 309 7.78E-69 T 31-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 TK1704 78f85f103a7d6fe64ec890b45fb808ed 179 Pfam PF06510 Protein of unknown function (DUF1102) 37 176 2.4E-55 T 31-10-2018 IPR009482 Protein of unknown function DUF1102 TK1643 9ee380464b953588bb336fd5a1dd8727 637 Pfam PF00037 4Fe-4S binding domain 606 628 7.8E-7 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TK1643 9ee380464b953588bb336fd5a1dd8727 637 SUPERFAMILY SSF52518 19 245 1.85E-56 T 31-10-2018 IPR029061 Thiamin diphosphate-binding fold TK1643 9ee380464b953588bb336fd5a1dd8727 637 Gene3D G3DSA:3.40.50.970 412 567 1.5E-23 T 31-10-2018 TK1643 9ee380464b953588bb336fd5a1dd8727 637 Gene3D G3DSA:3.40.50.970 10 198 3.4E-54 T 31-10-2018 TK1643 9ee380464b953588bb336fd5a1dd8727 637 SUPERFAMILY SSF52922 246 329 2.47E-7 T 31-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TK1643 9ee380464b953588bb336fd5a1dd8727 637 Gene3D G3DSA:3.30.70.20 568 637 8.0E-12 T 31-10-2018 TK1643 9ee380464b953588bb336fd5a1dd8727 637 PIRSF PIRSF006439 11 634 4.3E-225 T 31-10-2018 IPR017721 Indolepyruvate ferredoxin oxidoreductase, alpha subunit GO:0043805|GO:0055114 TK1643 9ee380464b953588bb336fd5a1dd8727 637 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 612 623 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TK1643 9ee380464b953588bb336fd5a1dd8727 637 Gene3D G3DSA:3.40.50.920 245 369 1.1E-5 T 31-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TK1643 9ee380464b953588bb336fd5a1dd8727 637 SUPERFAMILY SSF54862 564 632 2.37E-14 T 31-10-2018 TK1643 9ee380464b953588bb336fd5a1dd8727 637 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 33 215 2.3E-14 T 31-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 TK1643 9ee380464b953588bb336fd5a1dd8727 637 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 414 555 8.3E-32 T 31-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 TK1643 9ee380464b953588bb336fd5a1dd8727 637 TIGRFAM TIGR03336 IOR_alpha: indolepyruvate ferredoxin oxidoreductase, alpha subunit 21 627 4.7E-222 T 31-10-2018 IPR017721 Indolepyruvate ferredoxin oxidoreductase, alpha subunit GO:0043805|GO:0055114 TK1643 9ee380464b953588bb336fd5a1dd8727 637 SUPERFAMILY SSF52518 373 562 2.68E-38 T 31-10-2018 IPR029061 Thiamin diphosphate-binding fold TK1510 a1c75f09659c66a2760cd012dd77b0bb 79 Pfam PF07927 HicA toxin of bacterial toxin-antitoxin, 10 67 4.6E-15 T 31-10-2018 IPR012933 HicA mRNA interferase family GO:0003729 TK1510 a1c75f09659c66a2760cd012dd77b0bb 79 SUPERFAMILY SSF54786 4 73 7.45E-13 T 31-10-2018 TK1510 a1c75f09659c66a2760cd012dd77b0bb 79 Gene3D G3DSA:3.30.920.30 6 74 2.4E-15 T 31-10-2018 IPR038570 HicA superfamily TK1372 b3ef6c0501a84c362bb81190f3d130ae 61 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 12 40 2.0E-10 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 TK1372 b3ef6c0501a84c362bb81190f3d130ae 61 Gene3D G3DSA:2.10.260.10 6 47 5.1E-11 T 31-10-2018 TK1372 b3ef6c0501a84c362bb81190f3d130ae 61 SUPERFAMILY SSF89447 8 43 2.62E-9 T 31-10-2018 IPR037914 SpoVT-AbrB domain superfamily TK1372 b3ef6c0501a84c362bb81190f3d130ae 61 SMART SM00966 11 54 5.1E-5 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 TK1372 b3ef6c0501a84c362bb81190f3d130ae 61 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 12 45 6.9E-6 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 TK0149 2c6c4e3c4d257695404f06d255034123 157 PIRSF PIRSF005216 2 157 6.5E-47 T 31-10-2018 IPR002724 Pyruvoyl-dependent arginine decarboxylase GO:0006527|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 TK0149 2c6c4e3c4d257695404f06d255034123 157 Gene3D G3DSA:3.50.20.10 44 155 6.2E-35 T 31-10-2018 IPR016105 Pyruvoyl-dependent histidine/arginine decarboxylase, 3-layer sandwich domain GO:0006520|GO:0016831 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 TK0149 2c6c4e3c4d257695404f06d255034123 157 ProDom PD010449 DECARBOXYLASE PYRUVOYL-DEPENDENT ARGININE SUBUNIT ALPHA CONTAINS: BETA PVLARGDC LYA DECARBOX 6 141 8.0E-75 T 31-10-2018 IPR002724 Pyruvoyl-dependent arginine decarboxylase GO:0006527|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 TK0149 2c6c4e3c4d257695404f06d255034123 157 Gene3D G3DSA:3.30.60.30 1 43 3.7E-18 T 31-10-2018 TK0149 2c6c4e3c4d257695404f06d255034123 157 TIGRFAM TIGR00286 TIGR00286: arginine decarboxylase, pyruvoyl-dependent 6 153 1.1E-38 T 31-10-2018 IPR002724 Pyruvoyl-dependent arginine decarboxylase GO:0006527|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 TK0149 2c6c4e3c4d257695404f06d255034123 157 Hamap MF_01404 Pyruvoyl-dependent arginine decarboxylase [pdaD]. 1 157 46.971 T 31-10-2018 IPR002724 Pyruvoyl-dependent arginine decarboxylase GO:0006527|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 TK0149 2c6c4e3c4d257695404f06d255034123 157 SUPERFAMILY SSF56271 2 155 9.94E-47 T 31-10-2018 IPR016104 Pyruvoyl-dependent histidine/arginine decarboxylase GO:0006520|GO:0016831 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 TK0149 2c6c4e3c4d257695404f06d255034123 157 Pfam PF01862 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) 5 154 1.0E-40 T 31-10-2018 IPR002724 Pyruvoyl-dependent arginine decarboxylase GO:0006527|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 TK1748 631f8e9815008d4e79b1c0a0dc9adfa9 1065 Gene3D G3DSA:1.10.730.10 669 853 3.6E-54 T 31-10-2018 TK1748 631f8e9815008d4e79b1c0a0dc9adfa9 1065 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 42 53 8.6E-30 T 31-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 TK1748 631f8e9815008d4e79b1c0a0dc9adfa9 1065 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 545 558 8.6E-30 T 31-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 TK1748 631f8e9815008d4e79b1c0a0dc9adfa9 1065 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 223 246 8.6E-30 T 31-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 TK1748 631f8e9815008d4e79b1c0a0dc9adfa9 1065 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 584 593 8.6E-30 T 31-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 TK1748 631f8e9815008d4e79b1c0a0dc9adfa9 1065 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 399 414 8.6E-30 T 31-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 TK1748 631f8e9815008d4e79b1c0a0dc9adfa9 1065 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 20 663 5.8E-188 T 31-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 TK1748 631f8e9815008d4e79b1c0a0dc9adfa9 1065 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 9 876 0.0 T 31-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 TK1748 631f8e9815008d4e79b1c0a0dc9adfa9 1065 Hamap MF_02003 Isoleucine--tRNA ligase [ileS]. 3 1059 13.748 T 31-10-2018 IPR023586 Isoleucine-tRNA ligase, type 2 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 TK1748 631f8e9815008d4e79b1c0a0dc9adfa9 1065 Gene3D G3DSA:3.90.740.10 199 405 5.6E-233 T 31-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 TK1748 631f8e9815008d4e79b1c0a0dc9adfa9 1065 Pfam PF08264 Anticodon-binding domain of tRNA 711 862 2.7E-37 T 31-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 TK1748 631f8e9815008d4e79b1c0a0dc9adfa9 1065 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 49 60 - T 31-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 TK1748 631f8e9815008d4e79b1c0a0dc9adfa9 1065 SUPERFAMILY SSF52374 9 674 1.62E-133 T 31-10-2018 TK1748 631f8e9815008d4e79b1c0a0dc9adfa9 1065 Gene3D G3DSA:3.40.50.620 16 651 5.6E-233 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TK1748 631f8e9815008d4e79b1c0a0dc9adfa9 1065 SUPERFAMILY SSF47323 676 913 1.05E-61 T 31-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 TK1748 631f8e9815008d4e79b1c0a0dc9adfa9 1065 SUPERFAMILY SSF50677 203 401 4.81E-55 T 31-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 TK1748 631f8e9815008d4e79b1c0a0dc9adfa9 1065 SUPERFAMILY SSF47323 983 1049 1.44E-5 T 31-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 TK2163 04215dc00f2af76e32bdf98661138744 652 Gene3D G3DSA:3.60.9.10 2 228 1.5E-23 T 31-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily TK2163 04215dc00f2af76e32bdf98661138744 652 SUPERFAMILY SSF56228 3 228 2.75E-44 T 31-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily TK2163 04215dc00f2af76e32bdf98661138744 652 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 4 225 4.9E-41 T 31-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 TK2163 04215dc00f2af76e32bdf98661138744 652 SMART SM00790 1 226 9.5E-74 T 31-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 TK2163 04215dc00f2af76e32bdf98661138744 652 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 267 576 2.6E-19 T 31-10-2018 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 TK2163 04215dc00f2af76e32bdf98661138744 652 SUPERFAMILY SSF48310 241 650 4.32E-68 T 31-10-2018 IPR036021 Aldehyde ferredoxin oxidoreductase-like, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 TK2163 04215dc00f2af76e32bdf98661138744 652 Gene3D G3DSA:1.10.569.10 280 474 3.8E-13 T 31-10-2018 IPR013984 Aldehyde ferredoxin oxidoreductase, domain 2 TK1538 d585a399c5e8107c5c6efabaa10bfa10 133 SUPERFAMILY SSF54570 34 117 1.83E-31 T 31-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1538 d585a399c5e8107c5c6efabaa10bfa10 133 TIGRFAM TIGR01025 uS19_arch: ribosomal protein uS19 4 133 6.3E-67 T 31-10-2018 IPR005713 Ribosomal protein S19A/S15e GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1538 d585a399c5e8107c5c6efabaa10bfa10 133 PRINTS PR00975 Ribosomal protein S19 family signature 86 98 3.9E-19 T 31-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1538 d585a399c5e8107c5c6efabaa10bfa10 133 PRINTS PR00975 Ribosomal protein S19 family signature 66 85 3.9E-19 T 31-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1538 d585a399c5e8107c5c6efabaa10bfa10 133 PRINTS PR00975 Ribosomal protein S19 family signature 98 113 3.9E-19 T 31-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1538 d585a399c5e8107c5c6efabaa10bfa10 133 Gene3D G3DSA:3.30.860.20 2 133 5.4E-55 T 31-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1538 d585a399c5e8107c5c6efabaa10bfa10 133 Pfam PF00203 Ribosomal protein S19 35 116 2.5E-36 T 31-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1538 d585a399c5e8107c5c6efabaa10bfa10 133 ProSitePatterns PS00323 Ribosomal protein S19 signature. 86 110 - T 31-10-2018 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1538 d585a399c5e8107c5c6efabaa10bfa10 133 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 35 117 9.4E-27 T 31-10-2018 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 TK1538 d585a399c5e8107c5c6efabaa10bfa10 133 PIRSF PIRSF002144 1 133 4.6E-41 T 31-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1538 d585a399c5e8107c5c6efabaa10bfa10 133 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 33 122 25.746 T 31-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1819 004c20a633ed7b21608a03c5ed938a9a 514 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 345 475 2.3E-18 T 31-10-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain TK1819 004c20a633ed7b21608a03c5ed938a9a 514 Pfam PF01943 Polysaccharide biosynthesis protein 15 288 3.5E-25 T 31-10-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 TK1580 7952f567511b9929054af08e65702d51 169 Pfam PF03692 Putative zinc- or iron-chelating domain 16 116 1.0E-18 T 31-10-2018 IPR005358 Putative zinc- or iron-chelating domain containing protein TK1497 97212d895f19a1bf3f5feb89d8ba5c01 341 SMART SM01192 124 340 6.2E-12 T 31-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TK1497 97212d895f19a1bf3f5feb89d8ba5c01 341 SMART SM01193 4 119 1.1E-34 T 31-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TK1497 97212d895f19a1bf3f5feb89d8ba5c01 341 SUPERFAMILY SSF54826 1 123 2.69E-30 T 31-10-2018 TK1497 97212d895f19a1bf3f5feb89d8ba5c01 341 PRINTS PR00148 Enolase signature 92 108 9.1E-5 T 31-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TK1497 97212d895f19a1bf3f5feb89d8ba5c01 341 PRINTS PR00148 Enolase signature 316 330 9.1E-5 T 31-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TK1497 97212d895f19a1bf3f5feb89d8ba5c01 341 Pfam PF03952 Enolase, N-terminal domain 38 119 1.6E-22 T 31-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TK1497 97212d895f19a1bf3f5feb89d8ba5c01 341 Gene3D G3DSA:3.20.20.120 218 339 2.6E-13 T 31-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily TK1497 97212d895f19a1bf3f5feb89d8ba5c01 341 Gene3D G3DSA:3.30.390.10 1 112 1.3E-20 T 31-10-2018 IPR029017 Enolase-like, N-terminal TK1497 97212d895f19a1bf3f5feb89d8ba5c01 341 Pfam PF00113 Enolase, C-terminal TIM barrel domain 246 334 2.0E-7 T 31-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TK1497 97212d895f19a1bf3f5feb89d8ba5c01 341 SUPERFAMILY SSF51604 113 337 3.54E-32 T 31-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily TK0201 92a440eeed019e6cc3bfbd33a1d73a07 223 Hamap MF_00421 Phosphoribosylformylglycinamidine synthase subunit PurQ [purQ]. 2 219 45.084 T 31-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 TK0201 92a440eeed019e6cc3bfbd33a1d73a07 223 SUPERFAMILY SSF52317 2 221 6.39E-79 T 31-10-2018 IPR029062 Class I glutamine amidotransferase-like TK0201 92a440eeed019e6cc3bfbd33a1d73a07 223 PIRSF PIRSF001586 1 223 2.5E-84 T 31-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 TK0201 92a440eeed019e6cc3bfbd33a1d73a07 223 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 2 220 1.0E-51 T 31-10-2018 TK0201 92a440eeed019e6cc3bfbd33a1d73a07 223 TIGRFAM TIGR01737 FGAM_synth_I: phosphoribosylformylglycinamidine synthase I 2 220 1.9E-96 T 31-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 TK0201 92a440eeed019e6cc3bfbd33a1d73a07 223 SMART SM01211 1 221 1.8E-133 T 31-10-2018 TK0201 92a440eeed019e6cc3bfbd33a1d73a07 223 Gene3D G3DSA:3.40.50.880 1 223 1.1E-79 T 31-10-2018 IPR029062 Class I glutamine amidotransferase-like TK0230 54180901da2ff6766fa7d8eb82277322 291 SUPERFAMILY SSF52540 4 226 1.43E-48 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK0230 54180901da2ff6766fa7d8eb82277322 291 SMART SM00382 30 212 1.9E-10 T 31-10-2018 IPR003593 AAA+ ATPase domain TK0230 54180901da2ff6766fa7d8eb82277322 291 Pfam PF00005 ABC transporter 21 164 3.8E-25 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TK0230 54180901da2ff6766fa7d8eb82277322 291 Gene3D G3DSA:3.40.50.300 3 239 8.2E-51 T 31-10-2018 TK1034 3405d1a7897e838e83ea7b660f726761 296 Gene3D G3DSA:3.90.1570.30 10 140 2.0E-5 T 31-10-2018 TK1034 3405d1a7897e838e83ea7b660f726761 296 Pfam PF13588 Type I restriction enzyme R protein N terminus (HSDR_N) 32 126 1.4E-7 T 31-10-2018 IPR029464 Type I restriction enzyme R protein, N-terminal domain TK0453 732b471e65a194e6c80eec141851bd67 400 TIGRFAM TIGR01875 cas_MJ0381: CRISPR-associated autoregulator DevR family 193 343 3.0E-30 T 31-10-2018 IPR010154 CRISPR-associated protein Cas7/Cst2/DevR TK0453 732b471e65a194e6c80eec141851bd67 400 Pfam PF01905 CRISPR-associated negative auto-regulator DevR/Csa2 6 358 9.0E-76 T 31-10-2018 IPR010154 CRISPR-associated protein Cas7/Cst2/DevR TK1831 6e6d38ba2698739ae84b8e3f7b9130d8 350 SUPERFAMILY SSF55060 179 347 1.8E-43 T 31-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily TK1831 6e6d38ba2698739ae84b8e3f7b9130d8 350 Pfam PF10509 Galactokinase galactose-binding signature 3 35 4.6E-16 T 31-10-2018 IPR019539 Galactokinase galactose-binding domain GO:0005534 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 TK1831 6e6d38ba2698739ae84b8e3f7b9130d8 350 Pfam PF00288 GHMP kinases N terminal domain 92 155 5.6E-14 T 31-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 TK1831 6e6d38ba2698739ae84b8e3f7b9130d8 350 Pfam PF08544 GHMP kinases C terminal 249 328 1.2E-14 T 31-10-2018 IPR013750 GHMP kinase, C-terminal domain TK1831 6e6d38ba2698739ae84b8e3f7b9130d8 350 ProSitePatterns PS00106 Galactokinase signature. 7 18 - T 31-10-2018 IPR019741 Galactokinase, conserved site KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 TK1831 6e6d38ba2698739ae84b8e3f7b9130d8 350 Hamap MF_00246 Galactokinase [galK]. 5 349 39.36 T 31-10-2018 IPR022963 Galactokinase, bacterial GO:0004335|GO:0006012 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 TK1831 6e6d38ba2698739ae84b8e3f7b9130d8 350 Gene3D G3DSA:3.30.70.890 179 349 1.5E-59 T 31-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily TK1831 6e6d38ba2698739ae84b8e3f7b9130d8 350 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 95 106 - T 31-10-2018 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 TK1831 6e6d38ba2698739ae84b8e3f7b9130d8 350 SUPERFAMILY SSF54211 2 177 5.69E-53 T 31-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TK1831 6e6d38ba2698739ae84b8e3f7b9130d8 350 PRINTS PR00473 Galactokinase signature 233 247 1.9E-21 T 31-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 TK1831 6e6d38ba2698739ae84b8e3f7b9130d8 350 PRINTS PR00473 Galactokinase signature 86 104 1.9E-21 T 31-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 TK1831 6e6d38ba2698739ae84b8e3f7b9130d8 350 PRINTS PR00473 Galactokinase signature 7 25 1.9E-21 T 31-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 TK1831 6e6d38ba2698739ae84b8e3f7b9130d8 350 PRINTS PR00473 Galactokinase signature 66 77 1.9E-21 T 31-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 TK1831 6e6d38ba2698739ae84b8e3f7b9130d8 350 TIGRFAM TIGR00131 gal_kin: galactokinase 2 347 8.9E-80 T 31-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 TK1831 6e6d38ba2698739ae84b8e3f7b9130d8 350 PRINTS PR00959 Mevalonate kinase family signature 93 115 1.1E-41 T 31-10-2018 TK1831 6e6d38ba2698739ae84b8e3f7b9130d8 350 PRINTS PR00959 Mevalonate kinase family signature 136 155 1.1E-41 T 31-10-2018 TK1831 6e6d38ba2698739ae84b8e3f7b9130d8 350 PRINTS PR00959 Mevalonate kinase family signature 5 29 1.1E-41 T 31-10-2018 TK1831 6e6d38ba2698739ae84b8e3f7b9130d8 350 PRINTS PR00959 Mevalonate kinase family signature 296 313 1.1E-41 T 31-10-2018 TK1831 6e6d38ba2698739ae84b8e3f7b9130d8 350 Gene3D G3DSA:3.30.230.10 1 178 5.4E-61 T 31-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TK1831 6e6d38ba2698739ae84b8e3f7b9130d8 350 PIRSF PIRSF000530 1 350 5.5E-110 T 31-10-2018 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 TK1766 af3cf9586fe5f8e295651dffec0e31a2 361 SUPERFAMILY SSF102114 27 207 5.1E-24 T 31-10-2018 TK1766 af3cf9586fe5f8e295651dffec0e31a2 361 Gene3D G3DSA:3.20.20.70 24 270 1.1E-16 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TK1766 af3cf9586fe5f8e295651dffec0e31a2 361 ProSitePatterns PS01087 Radical activating enzymes signature. 23 45 - T 31-10-2018 IPR001989 Radical-activating enzyme, conserved site GO:0016491|GO:0051539|GO:0055114 TK1766 af3cf9586fe5f8e295651dffec0e31a2 361 Pfam PF04055 Radical SAM superfamily 33 186 6.0E-12 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TK1766 af3cf9586fe5f8e295651dffec0e31a2 361 Pfam PF13394 4Fe-4S single cluster domain 31 122 5.3E-6 T 31-10-2018 TK1234 8e922d0957bdb50ca2ea758863e3133f 92 SUPERFAMILY SSF82649 4 86 4.29E-11 T 31-10-2018 TK1234 8e922d0957bdb50ca2ea758863e3133f 92 Gene3D G3DSA:3.30.390.50 1 88 9.1E-27 T 31-10-2018 TK1234 8e922d0957bdb50ca2ea758863e3133f 92 Pfam PF10437 Bacterial lipoate protein ligase C-terminus 7 64 4.2E-7 T 31-10-2018 IPR019491 Lipoate protein ligase, C-terminal KEGG: 00785+6.3.1.20 TK0570 a811e0fea0b366402076aa336b05b963 484 Pfam PF13416 Bacterial extracellular solute-binding protein 91 326 1.3E-20 T 31-10-2018 IPR006059 Bacterial extracellular solute-binding protein TK0570 a811e0fea0b366402076aa336b05b963 484 Gene3D G3DSA:3.40.190.10 89 318 2.2E-34 T 31-10-2018 TK0570 a811e0fea0b366402076aa336b05b963 484 Gene3D G3DSA:3.40.190.10 154 273 2.2E-34 T 31-10-2018 TK0570 a811e0fea0b366402076aa336b05b963 484 SUPERFAMILY SSF53850 83 323 2.24E-40 T 31-10-2018 TK0020 ae715c96e5103e37a825cb2491184ed2 243 SUPERFAMILY SSF160945 1 242 1.83E-83 T 31-10-2018 TK0020 ae715c96e5103e37a825cb2491184ed2 243 Gene3D G3DSA:1.10.3490.10 139 231 1.1E-104 T 31-10-2018 TK0020 ae715c96e5103e37a825cb2491184ed2 243 Gene3D G3DSA:3.40.50.10620 1 234 1.1E-104 T 31-10-2018 TK0020 ae715c96e5103e37a825cb2491184ed2 243 ProDom PD038575 MJECL12 PLASMID PH0156 1 238 2.0E-118 T 31-10-2018 IPR024508 Protein of unknown function DUF3226 TK0020 ae715c96e5103e37a825cb2491184ed2 243 Pfam PF11536 Protein of unknown function (DUF3226) 3 241 8.8E-112 T 31-10-2018 IPR024508 Protein of unknown function DUF3226 TK1841 3f6ecbf1bab1d3be39e0dc37330cd231 202 Gene3D G3DSA:3.40.50.1390 54 154 2.0E-28 T 31-10-2018 TK1841 3f6ecbf1bab1d3be39e0dc37330cd231 202 Pfam PF12728 Helix-turn-helix domain 3 51 7.3E-14 T 31-10-2018 TK1841 3f6ecbf1bab1d3be39e0dc37330cd231 202 SUPERFAMILY SSF46955 2 50 2.38E-5 T 31-10-2018 IPR009061 Putative DNA-binding domain superfamily TK1841 3f6ecbf1bab1d3be39e0dc37330cd231 202 ProSitePatterns PS00397 Site-specific recombinases active site. 60 68 - T 31-10-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 TK1841 3f6ecbf1bab1d3be39e0dc37330cd231 202 SMART SM00857 57 180 3.9E-28 T 31-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 TK1841 3f6ecbf1bab1d3be39e0dc37330cd231 202 Pfam PF00239 Resolvase, N terminal domain 57 189 3.9E-25 T 31-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 TK1841 3f6ecbf1bab1d3be39e0dc37330cd231 202 Gene3D G3DSA:1.10.1660.10 2 52 3.1E-6 T 31-10-2018 TK1841 3f6ecbf1bab1d3be39e0dc37330cd231 202 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 4 50 1.5E-13 T 31-10-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 TK1841 3f6ecbf1bab1d3be39e0dc37330cd231 202 SUPERFAMILY SSF53041 56 188 5.89E-26 T 31-10-2018 IPR036162 Resolvase-like, N-terminal catalytic domain superfamily GO:0000150|GO:0003677|GO:0006310 TK0334 9db7d9d38f9f9c419f942fdef3a4546e 129 Gene3D G3DSA:3.40.50.1010 1 124 3.8E-27 T 31-10-2018 TK0334 9db7d9d38f9f9c419f942fdef3a4546e 129 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 2 121 11.93 T 31-10-2018 IPR022907 VapC family GO:0004540 TK0334 9db7d9d38f9f9c419f942fdef3a4546e 129 Pfam PF01850 PIN domain 2 109 4.4E-16 T 31-10-2018 IPR002716 PIN domain TK0334 9db7d9d38f9f9c419f942fdef3a4546e 129 SUPERFAMILY SSF88723 1 123 5.05E-30 T 31-10-2018 IPR029060 PIN-like domain superfamily TK1161 1a275aa5f02b15f9238ff32ae5f16096 272 Pfam PF00809 Pterin binding enzyme 14 252 7.5E-61 T 31-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TK1161 1a275aa5f02b15f9238ff32ae5f16096 272 SUPERFAMILY SSF51717 7 269 9.29E-81 T 31-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TK1161 1a275aa5f02b15f9238ff32ae5f16096 272 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 13 265 1.3E-71 T 31-10-2018 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 TK1161 1a275aa5f02b15f9238ff32ae5f16096 272 Gene3D G3DSA:3.20.20.20 2 271 1.8E-90 T 31-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TK1975 87116d05cd11fe925a029d19249e7072 512 Gene3D G3DSA:1.25.10.10 283 457 6.9E-10 T 31-10-2018 IPR011989 Armadillo-like helical TK1975 87116d05cd11fe925a029d19249e7072 512 Gene3D G3DSA:1.25.10.10 10 272 1.9E-21 T 31-10-2018 IPR011989 Armadillo-like helical TK1975 87116d05cd11fe925a029d19249e7072 512 SUPERFAMILY SSF48371 41 459 3.1E-39 T 31-10-2018 IPR016024 Armadillo-type fold TK1627 99790710f6b1ec0223221606892087b7 334 Pfam PF00742 Homoserine dehydrogenase 156 327 6.6E-51 T 31-10-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 TK1627 99790710f6b1ec0223221606892087b7 334 Gene3D G3DSA:3.40.50.720 6 327 3.9E-95 T 31-10-2018 TK1627 99790710f6b1ec0223221606892087b7 334 SUPERFAMILY SSF55347 156 314 7.19E-40 T 31-10-2018 TK1627 99790710f6b1ec0223221606892087b7 334 PIRSF PIRSF036497 1 334 9.0E-88 T 31-10-2018 IPR022697 Homoserine dehydrogenase lacking ACT domain GO:0004412 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 TK1627 99790710f6b1ec0223221606892087b7 334 Gene3D G3DSA:3.30.360.10 167 310 3.9E-95 T 31-10-2018 TK1627 99790710f6b1ec0223221606892087b7 334 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 10 147 2.1E-6 T 31-10-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 TK1627 99790710f6b1ec0223221606892087b7 334 SUPERFAMILY SSF51735 3 177 6.64E-31 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily TK1627 99790710f6b1ec0223221606892087b7 334 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 201 223 - T 31-10-2018 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 TK2131 ec4f0552cff465f3baa83b74e2b00753 83 Gene3D G3DSA:1.20.1440.50 1 83 8.5E-31 T 31-10-2018 IPR023130 Ta0600-like superfamily TK2131 ec4f0552cff465f3baa83b74e2b00753 83 ProDom PD029943 UPF0147 ARCHAEAL PF0239 ST0460.1 MM1385 CYTOSOLIC SACI_0891 TV0625 APES069 TA0600 1 83 3.0E-40 T 31-10-2018 IPR005354 Uncharacterised protein family UPF0147 TK2131 ec4f0552cff465f3baa83b74e2b00753 83 SUPERFAMILY SSF158436 3 83 5.36E-30 T 31-10-2018 TK2131 ec4f0552cff465f3baa83b74e2b00753 83 Hamap MF_00342 UPF0147 protein . 1 83 29.41 T 31-10-2018 IPR005354 Uncharacterised protein family UPF0147 TK2131 ec4f0552cff465f3baa83b74e2b00753 83 Pfam PF03685 Uncharacterised protein family (UPF0147) 2 82 5.9E-33 T 31-10-2018 IPR005354 Uncharacterised protein family UPF0147 TK1611 403401fc33a14f3b3d6d41f931824e49 281 Gene3D G3DSA:3.20.20.140 3 280 1.6E-27 T 31-10-2018 TK1611 403401fc33a14f3b3d6d41f931824e49 281 SUPERFAMILY SSF51556 1 278 4.33E-32 T 31-10-2018 IPR032466 Metal-dependent hydrolase TK1611 403401fc33a14f3b3d6d41f931824e49 281 ProDom PD038341 HYDROLASE COFACTOR MOLYBDENUM BIOSYNTHESIS METAL-DEPENDENT DEOXYRIBONUCLEASE PREDICTED TATD-RELATED TVG0313409 A 124 280 5.0E-87 T 31-10-2018 TK1611 403401fc33a14f3b3d6d41f931824e49 281 PIRSF PIRSF004961 1 281 1.2E-123 T 31-10-2018 IPR011589 Protein of unknown function UCP004961 TK1611 403401fc33a14f3b3d6d41f931824e49 281 Pfam PF01026 TatD related DNase 5 275 2.1E-31 T 31-10-2018 IPR001130 TatD family GO:0016788 TK0283 371c042e11b6589b8dcebefd32900ea9 361 Gene3D G3DSA:3.20.20.70 1 261 6.3E-78 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TK0283 371c042e11b6589b8dcebefd32900ea9 361 TIGRFAM TIGR02146 LysS_fung_arch: homocitrate synthase 2 342 1.8E-147 T 31-10-2018 IPR011872 Homocitrate synthase, fungi/archaea GO:0004410|GO:0019752|GO:0019878|GO:0046912 KEGG: 00300+2.3.3.14|KEGG: 00620+2.3.3.14|MetaCyc: PWY-3081|MetaCyc: PWY-7710 TK0283 371c042e11b6589b8dcebefd32900ea9 361 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 185 198 - T 31-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 TK0283 371c042e11b6589b8dcebefd32900ea9 361 SUPERFAMILY SSF51569 2 273 9.96E-74 T 31-10-2018 TK0283 371c042e11b6589b8dcebefd32900ea9 361 Gene3D G3DSA:1.10.238.260 262 360 8.3E-20 T 31-10-2018 TK0283 371c042e11b6589b8dcebefd32900ea9 361 Pfam PF00682 HMGL-like 3 255 2.2E-59 T 31-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 TK1215 152111bb9ff86dcd02b7ee83cbe1e9dc 394 ProSitePatterns PS00535 Respiratory chain NADH dehydrogenase 49 Kd subunit signature. 64 75 - T 31-10-2018 IPR014029 NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TK1215 152111bb9ff86dcd02b7ee83cbe1e9dc 394 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 142 394 6.2E-73 T 31-10-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TK1215 152111bb9ff86dcd02b7ee83cbe1e9dc 394 SUPERFAMILY SSF56762 41 394 3.66E-95 T 31-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TK1215 152111bb9ff86dcd02b7ee83cbe1e9dc 394 Gene3D G3DSA:1.10.645.20 30 394 3.0E-115 T 31-10-2018 IPR038290 NADH-quinone oxidoreductase, subunit D superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TK0409 aa3b97dcb4b67bfea7721cffc80a841a 145 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 14 51 1.2E-10 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 TK0409 aa3b97dcb4b67bfea7721cffc80a841a 145 PIRSF PIRSF019240 1 143 8.3E-31 T 31-10-2018 IPR016752 Uncharacterised conserved protein UCP019240, SpoVT/AbrB-related TK0409 aa3b97dcb4b67bfea7721cffc80a841a 145 Gene3D G3DSA:2.10.260.10 5 103 1.3E-27 T 31-10-2018 TK0409 aa3b97dcb4b67bfea7721cffc80a841a 145 SUPERFAMILY SSF89447 12 44 2.09E-8 T 31-10-2018 IPR037914 SpoVT-AbrB domain superfamily TK0409 aa3b97dcb4b67bfea7721cffc80a841a 145 SMART SM00966 13 56 1.3E-5 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 TK0194 aefd4a3c9d3ccfc0e18f0d96bc45fcfb 486 SMART SM00116 160 208 5.3E-17 T 31-10-2018 IPR000644 CBS domain TK0194 aefd4a3c9d3ccfc0e18f0d96bc45fcfb 486 SMART SM00116 102 150 1.4E-11 T 31-10-2018 IPR000644 CBS domain TK0194 aefd4a3c9d3ccfc0e18f0d96bc45fcfb 486 SMART SM01240 13 471 5.1E-269 T 31-10-2018 TK0194 aefd4a3c9d3ccfc0e18f0d96bc45fcfb 486 SUPERFAMILY SSF51412 10 475 8.24E-113 T 31-10-2018 TK0194 aefd4a3c9d3ccfc0e18f0d96bc45fcfb 486 Pfam PF00571 CBS domain 153 206 1.1E-15 T 31-10-2018 IPR000644 CBS domain TK0194 aefd4a3c9d3ccfc0e18f0d96bc45fcfb 486 Pfam PF00571 CBS domain 100 147 1.0E-13 T 31-10-2018 IPR000644 CBS domain TK0194 aefd4a3c9d3ccfc0e18f0d96bc45fcfb 486 Gene3D G3DSA:3.20.20.70 3 484 1.4E-200 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TK0194 aefd4a3c9d3ccfc0e18f0d96bc45fcfb 486 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 292 304 - T 31-10-2018 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 TK0194 aefd4a3c9d3ccfc0e18f0d96bc45fcfb 486 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 14 453 7.9E-193 T 31-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 TK0194 aefd4a3c9d3ccfc0e18f0d96bc45fcfb 486 SUPERFAMILY SSF54631 71 205 3.12E-34 T 31-10-2018 TK0194 aefd4a3c9d3ccfc0e18f0d96bc45fcfb 486 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 14 471 1.6E-148 T 31-10-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 TK0194 aefd4a3c9d3ccfc0e18f0d96bc45fcfb 486 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 14 484 80.459 T 31-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 TK0194 aefd4a3c9d3ccfc0e18f0d96bc45fcfb 486 PIRSF PIRSF000130 3 486 8.6E-197 T 31-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 TK2200 02f249d6a1ca0ed4077c5ba51f69bdf0 448 Gene3D G3DSA:3.40.50.720 3 132 9.9E-9 T 31-10-2018 TK2200 02f249d6a1ca0ed4077c5ba51f69bdf0 448 SUPERFAMILY SSF52540 125 299 1.61E-12 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK2200 02f249d6a1ca0ed4077c5ba51f69bdf0 448 Gene3D G3DSA:3.40.50.300 211 306 1.1E-8 T 31-10-2018 TK2200 02f249d6a1ca0ed4077c5ba51f69bdf0 448 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 241 299 1.4E-5 T 31-10-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain TK2171 ea8222f7926dbfa4cd0744cd0b9d9cbc 219 Gene3D G3DSA:3.40.50.11570 3 215 4.2E-64 T 31-10-2018 TK2171 ea8222f7926dbfa4cd0744cd0b9d9cbc 219 Pfam PF03192 Pyrococcus protein of unknown function, DUF257 8 209 3.5E-72 T 31-10-2018 IPR005489 Protein of unknown function DUF257 TK0924 639b16afeefd23bb5847744cc0d0823a 147 SUPERFAMILY SSF88723 12 142 5.89E-12 T 31-10-2018 IPR029060 PIN-like domain superfamily TK0924 639b16afeefd23bb5847744cc0d0823a 147 TIGRFAM TIGR00305 TIGR00305: putative toxin-antitoxin system toxin component, PIN family 12 131 2.4E-8 T 31-10-2018 IPR002850 PIN family, putative toxin-antitoxin system toxin component TK0924 639b16afeefd23bb5847744cc0d0823a 147 Gene3D G3DSA:3.40.50.1010 11 137 3.3E-7 T 31-10-2018 TK0924 639b16afeefd23bb5847744cc0d0823a 147 Pfam PF10130 PIN domain 13 132 2.2E-23 T 31-10-2018 IPR002716 PIN domain TK1972 ac28fcca1abbb456f0de43abad39ffd8 343 SUPERFAMILY SSF48452 130 326 1.01E-22 T 31-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TK1972 ac28fcca1abbb456f0de43abad39ffd8 343 Pfam PF13429 Tetratricopeptide repeat 165 312 2.6E-8 T 31-10-2018 TK1972 ac28fcca1abbb456f0de43abad39ffd8 343 Gene3D G3DSA:1.25.40.10 111 337 1.6E-16 T 31-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TK1972 ac28fcca1abbb456f0de43abad39ffd8 343 SUPERFAMILY SSF103473 11 105 2.49E-5 T 31-10-2018 IPR036259 MFS transporter superfamily TK0804 366281b2d9b1f23d8defa94a31134ee5 273 SUPERFAMILY SSF81345 3 272 8.11E-19 T 31-10-2018 IPR037294 ABC transporter, BtuC-like TK0804 366281b2d9b1f23d8defa94a31134ee5 273 Pfam PF00950 ABC 3 transport family 4 266 2.6E-27 T 31-10-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 TK1158 7a8f3721a725a59b9f75c98372227b3c 1125 SUPERFAMILY SSF53335 344 719 4.11E-43 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TK1158 7a8f3721a725a59b9f75c98372227b3c 1125 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 364 380 8.1E-14 T 31-10-2018 TK1158 7a8f3721a725a59b9f75c98372227b3c 1125 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 390 404 8.1E-14 T 31-10-2018 TK1158 7a8f3721a725a59b9f75c98372227b3c 1125 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 634 658 8.1E-14 T 31-10-2018 TK1158 7a8f3721a725a59b9f75c98372227b3c 1125 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 587 599 8.1E-14 T 31-10-2018 TK1158 7a8f3721a725a59b9f75c98372227b3c 1125 Pfam PF02384 N-6 DNA Methylase 358 421 1.1E-6 T 31-10-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 TK1158 7a8f3721a725a59b9f75c98372227b3c 1125 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 590 596 - T 31-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 TK2185 642152d048540016b429e757b216d162 449 Gene3D G3DSA:3.30.310.50 360 448 5.5E-21 T 31-10-2018 TK2185 642152d048540016b429e757b216d162 449 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 89 103 1.6E-14 T 31-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TK2185 642152d048540016b429e757b216d162 449 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 165 184 1.6E-14 T 31-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TK2185 642152d048540016b429e757b216d162 449 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 226 241 1.6E-14 T 31-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TK2185 642152d048540016b429e757b216d162 449 SUPERFAMILY SSF53738 252 355 5.89E-23 T 31-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TK2185 642152d048540016b429e757b216d162 449 TIGRFAM TIGR03990 Arch_GlmM: phosphoglucosamine mutase 3 441 5.1E-164 T 31-10-2018 IPR024086 Phosphoglucosamine mutase, archaeal type GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TK2185 642152d048540016b429e757b216d162 449 SUPERFAMILY SSF55957 348 447 2.49E-23 T 31-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TK2185 642152d048540016b429e757b216d162 449 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 254 357 2.9E-19 T 31-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TK2185 642152d048540016b429e757b216d162 449 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 90 99 - T 31-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TK2185 642152d048540016b429e757b216d162 449 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 3 132 9.9E-44 T 31-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TK2185 642152d048540016b429e757b216d162 449 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 151 246 1.3E-19 T 31-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TK2185 642152d048540016b429e757b216d162 449 Gene3D G3DSA:3.40.120.10 1 147 4.0E-51 T 31-10-2018 TK2185 642152d048540016b429e757b216d162 449 Gene3D G3DSA:3.40.120.10 247 330 2.8E-54 T 31-10-2018 TK2185 642152d048540016b429e757b216d162 449 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 366 435 1.3E-7 T 31-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TK2185 642152d048540016b429e757b216d162 449 Hamap MF_01554_A Phosphoglucosamine mutase [glmM]. 2 446 51.974 T 31-10-2018 IPR023666 Phosphoglucosamine mutase, archaeal GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TK2185 642152d048540016b429e757b216d162 449 Gene3D G3DSA:3.40.120.10 164 345 2.8E-54 T 31-10-2018 TK2185 642152d048540016b429e757b216d162 449 SUPERFAMILY SSF53738 150 249 5.1E-23 T 31-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TK2185 642152d048540016b429e757b216d162 449 SUPERFAMILY SSF53738 3 171 2.44E-45 T 31-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TK1701 3ce3d6ef7d4de2d2f90f333b6ddeb9ca 320 Pfam PF17231 Family of unknown function (DUF5305) 120 317 9.6E-11 T 31-10-2018 IPR035185 Protein of unknown function DUF5305 TK0492 6e46f23e4729b85e62e38feac8375bb9 438 SUPERFAMILY SSF50249 1 102 2.57E-27 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold TK0492 6e46f23e4729b85e62e38feac8375bb9 438 Gene3D G3DSA:3.30.930.10 107 438 2.8E-123 T 31-10-2018 TK0492 6e46f23e4729b85e62e38feac8375bb9 438 PRINTS PR01042 Aspartyl-tRNA synthetase signature 393 407 1.7E-23 T 31-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 TK0492 6e46f23e4729b85e62e38feac8375bb9 438 PRINTS PR01042 Aspartyl-tRNA synthetase signature 204 217 1.7E-23 T 31-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 TK0492 6e46f23e4729b85e62e38feac8375bb9 438 PRINTS PR01042 Aspartyl-tRNA synthetase signature 187 199 1.7E-23 T 31-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 TK0492 6e46f23e4729b85e62e38feac8375bb9 438 PRINTS PR01042 Aspartyl-tRNA synthetase signature 353 369 1.7E-23 T 31-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 TK0492 6e46f23e4729b85e62e38feac8375bb9 438 Hamap MF_02075 Aspartate--tRNA(Asp) ligase [aspS]. 2 438 43.539 T 31-10-2018 IPR004523 Aspartate-tRNA synthetase, type 2 GO:0000166|GO:0004815|GO:0005524|GO:0005737|GO:0006422 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 TK0492 6e46f23e4729b85e62e38feac8375bb9 438 Pfam PF01336 OB-fold nucleic acid binding domain 19 97 1.0E-11 T 31-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 TK0492 6e46f23e4729b85e62e38feac8375bb9 438 Pfam PF00152 tRNA synthetases class II (D, K and N) 118 432 5.1E-96 T 31-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 TK0492 6e46f23e4729b85e62e38feac8375bb9 438 TIGRFAM TIGR00458 aspS_nondisc: aspartate--tRNA(Asn) ligase 5 438 1.0E-185 T 31-10-2018 IPR004523 Aspartate-tRNA synthetase, type 2 GO:0000166|GO:0004815|GO:0005524|GO:0005737|GO:0006422 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 TK0492 6e46f23e4729b85e62e38feac8375bb9 438 Gene3D G3DSA:2.40.50.140 1 105 1.3E-27 T 31-10-2018 TK0492 6e46f23e4729b85e62e38feac8375bb9 438 SUPERFAMILY SSF55681 95 437 2.77E-100 T 31-10-2018 TK0269 27de9ab27e90c1204a0d79b28b1a6d9e 306 SMART SM00861 3 168 9.8E-54 T 31-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain TK0269 27de9ab27e90c1204a0d79b28b1a6d9e 306 Pfam PF02780 Transketolase, C-terminal domain 177 297 4.3E-32 T 31-10-2018 IPR033248 Transketolase, C-terminal domain TK0269 27de9ab27e90c1204a0d79b28b1a6d9e 306 SUPERFAMILY SSF52518 4 169 8.03E-56 T 31-10-2018 IPR029061 Thiamin diphosphate-binding fold TK0269 27de9ab27e90c1204a0d79b28b1a6d9e 306 Gene3D G3DSA:3.40.50.920 177 306 1.3E-38 T 31-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TK0269 27de9ab27e90c1204a0d79b28b1a6d9e 306 SUPERFAMILY SSF52922 174 302 2.09E-34 T 31-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TK0269 27de9ab27e90c1204a0d79b28b1a6d9e 306 Pfam PF02779 Transketolase, pyrimidine binding domain 5 164 1.9E-36 T 31-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain TK0269 27de9ab27e90c1204a0d79b28b1a6d9e 306 Gene3D G3DSA:3.40.50.970 2 176 2.4E-61 T 31-10-2018 TK1807 2e7587d175969cc92f8df910c3c6de98 302 Gene3D G3DSA:3.20.20.70 52 283 3.6E-30 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TK1807 2e7587d175969cc92f8df910c3c6de98 302 Pfam PF04055 Radical SAM superfamily 103 211 7.2E-13 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TK1807 2e7587d175969cc92f8df910c3c6de98 302 SMART SM00729 57 254 1.2E-5 T 31-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TK1807 2e7587d175969cc92f8df910c3c6de98 302 SUPERFAMILY SSF102114 61 262 8.24E-31 T 31-10-2018 TK0056 e40a14ca24322ffccf663464367acd61 189 SMART SM01022 4 104 4.2E-26 T 31-10-2018 IPR007374 ASCH domain TK0056 e40a14ca24322ffccf663464367acd61 189 SUPERFAMILY SSF88697 1 103 8.62E-23 T 31-10-2018 IPR015947 PUA-like superfamily TK0056 e40a14ca24322ffccf663464367acd61 189 Pfam PF04266 ASCH domain 4 103 7.9E-18 T 31-10-2018 IPR007374 ASCH domain TK1404 2a5a2cccb56f53e07419e51fe0704acd 236 SUPERFAMILY SSF53738 127 208 4.24E-7 T 31-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TK1404 2a5a2cccb56f53e07419e51fe0704acd 236 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 7 67 1.2E-5 T 31-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TK1404 2a5a2cccb56f53e07419e51fe0704acd 236 Gene3D G3DSA:3.40.120.10 3 80 9.3E-7 T 31-10-2018 TK1404 2a5a2cccb56f53e07419e51fe0704acd 236 SUPERFAMILY SSF53738 7 69 2.67E-7 T 31-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TK0991 cf6f601ed662024ccd6146196b9da533 579 Pfam PF02554 Carbon starvation protein CstA 1 361 3.5E-111 T 31-10-2018 IPR003706 CstA, N-terminal domain GO:0009267|GO:0016020 TK0991 cf6f601ed662024ccd6146196b9da533 579 Pfam PF13722 5TM C-terminal transporter carbon starvation CstA 404 527 2.0E-30 T 31-10-2018 IPR025299 CstA, C-terminal domain TK1046 3449e1f98bed9719f4b1688a0acaecc1 1319 SUPERFAMILY SSF52317 1082 1318 1.99E-23 T 31-10-2018 IPR029062 Class I glutamine amidotransferase-like TK1046 3449e1f98bed9719f4b1688a0acaecc1 1319 Gene3D G3DSA:3.40.50.880 1102 1306 3.6E-10 T 31-10-2018 IPR029062 Class I glutamine amidotransferase-like TK1046 3449e1f98bed9719f4b1688a0acaecc1 1319 Gene3D G3DSA:2.60.40.10 405 505 3.2E-6 T 31-10-2018 IPR013783 Immunoglobulin-like fold TK1046 3449e1f98bed9719f4b1688a0acaecc1 1319 Pfam PF09822 ABC-type uncharacterized transport system 1123 1194 5.4E-8 T 31-10-2018 IPR019196 ABC-type uncharacterised transport system Reactome: R-HSA-5610787|Reactome: R-HSA-5620924 TK1734 9f15863e715fab57a2c67a322328631b 268 Gene3D G3DSA:3.40.50.1000 72 188 8.4E-94 T 31-10-2018 IPR023214 HAD superfamily TK1734 9f15863e715fab57a2c67a322328631b 268 Pfam PF13242 HAD-hyrolase-like 188 260 7.4E-19 T 31-10-2018 TK1734 9f15863e715fab57a2c67a322328631b 268 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 7 236 1.4E-48 T 31-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA TK1734 9f15863e715fab57a2c67a322328631b 268 Gene3D G3DSA:3.40.50.1000 8 254 8.4E-94 T 31-10-2018 IPR023214 HAD superfamily TK1734 9f15863e715fab57a2c67a322328631b 268 PIRSF PIRSF000915 5 266 3.3E-64 T 31-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA TK1734 9f15863e715fab57a2c67a322328631b 268 SUPERFAMILY SSF56784 6 260 3.2E-66 T 31-10-2018 IPR036412 HAD-like superfamily TK1734 9f15863e715fab57a2c67a322328631b 268 Pfam PF13344 Haloacid dehalogenase-like hydrolase 7 106 6.7E-28 T 31-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA TK1110 0bb7df1ca3c213621827088507d2c22b 453 Gene3D G3DSA:3.40.1190.20 24 447 2.1E-151 T 31-10-2018 IPR029056 Ribokinase-like TK1110 0bb7df1ca3c213621827088507d2c22b 453 Gene3D G3DSA:3.30.1110.20 31 203 2.1E-151 T 31-10-2018 TK1110 0bb7df1ca3c213621827088507d2c22b 453 Hamap MF_00809 ADP-dependent glucokinase [glkA]. 1 453 59.483 T 31-10-2018 IPR031299 ADP-dependent glucokinase, archaeal KEGG: 00010+2.7.1.147|MetaCyc: PWY-6855 TK1110 0bb7df1ca3c213621827088507d2c22b 453 SUPERFAMILY SSF53613 2 452 2.45E-156 T 31-10-2018 IPR029056 Ribokinase-like TK1110 0bb7df1ca3c213621827088507d2c22b 453 PIRSF PIRSF015883 9 453 2.4E-160 T 31-10-2018 IPR015990 ADP-specific phosphofructokinase/glucokinase, archaeal GO:0000287|GO:0006096|GO:0016773 TK1110 0bb7df1ca3c213621827088507d2c22b 453 Pfam PF04587 ADP-specific Phosphofructokinase/Glucokinase conserved region 23 447 1.3E-95 T 31-10-2018 IPR007666 ADP-specific phosphofructokinase/glucokinase GO:0005975|GO:0016773 Reactome: R-HSA-70171 TK0002 4f9cc936717f1d05ffb95b09650270ca 215 Pfam PF01863 Protein of unknown function DUF45 11 197 1.0E-48 T 31-10-2018 IPR002725 Protein of unknown function DUF45 TK0002 4f9cc936717f1d05ffb95b09650270ca 215 Gene3D G3DSA:3.30.2010.10 107 200 2.8E-20 T 31-10-2018 TK1495 7d768394277610b23196d40e8ee634aa 51 Gene3D G3DSA:2.20.28.70 1 48 2.6E-18 T 31-10-2018 IPR038587 Ribosomal protein L40e superfamily Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 TK1495 7d768394277610b23196d40e8ee634aa 51 Hamap MF_00788 50S ribosomal protein L40e [rpl40e]. 2 47 19.187 T 31-10-2018 IPR023657 Ribosomal protein L40e, archaeal GO:0003735|GO:0005840|GO:0006412 TK1495 7d768394277610b23196d40e8ee634aa 51 SMART SM01377 1 46 7.2E-9 T 31-10-2018 IPR001975 Ribosomal protein L40e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 TK1495 7d768394277610b23196d40e8ee634aa 51 SUPERFAMILY SSF57829 2 46 8.79E-16 T 31-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 TK1596 b724b72f2d30c1d4550b6e869f9814d1 103 Pfam PF16999 Vacuolar (H+)-ATPase G subunit 6 79 8.4E-7 T 31-10-2018 TK1596 b724b72f2d30c1d4550b6e869f9814d1 103 TIGRFAM TIGR02926 AhaH: ATP synthase archaeal, H subunit 5 89 2.2E-16 T 31-10-2018 IPR014275 ATPase, A1A0, subunit H TK1596 b724b72f2d30c1d4550b6e869f9814d1 103 SUPERFAMILY SSF81573 18 73 6.1E-7 T 31-10-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain superfamily TK2302 a1a30866d65ccd9bb4a96e9059e91e55 416 TIGRFAM TIGR00094 tRNA_TruD_broad: tRNA pseudouridine synthase, TruD family 12 415 7.7E-85 T 31-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 TK2302 a1a30866d65ccd9bb4a96e9059e91e55 416 SUPERFAMILY SSF55120 7 414 5.04E-94 T 31-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 TK2302 a1a30866d65ccd9bb4a96e9059e91e55 416 Gene3D G3DSA:3.30.70.3160 43 125 3.6E-120 T 31-10-2018 TK2302 a1a30866d65ccd9bb4a96e9059e91e55 416 Gene3D G3DSA:3.30.2350.20 126 411 3.6E-120 T 31-10-2018 TK2302 a1a30866d65ccd9bb4a96e9059e91e55 416 Hamap MF_01082 tRNA pseudouridine synthase D [truD]. 8 416 29.5 T 31-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 TK2302 a1a30866d65ccd9bb4a96e9059e91e55 416 ProSitePatterns PS01268 Uncharacterized protein family UPF0024 signature. 80 93 - T 31-10-2018 IPR020119 Pseudouridine synthase TruD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 Reactome: R-HSA-6782315 TK2302 a1a30866d65ccd9bb4a96e9059e91e55 416 Gene3D G3DSA:1.10.1510.30 171 256 3.6E-120 T 31-10-2018 TK2302 a1a30866d65ccd9bb4a96e9059e91e55 416 Pfam PF01142 tRNA pseudouridine synthase D (TruD) 12 412 2.2E-136 T 31-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 TK2302 a1a30866d65ccd9bb4a96e9059e91e55 416 PIRSF PIRSF037016 33 394 1.2E-63 T 31-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 TK2302 a1a30866d65ccd9bb4a96e9059e91e55 416 PIRSF PIRSF037016 389 416 0.0049 T 31-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 TK2103 8804a587a721d7e6f96879c6c3dffeff 97 ProDom PD029791 ORF 3'REGION GAP PF1875 PF0899 PH1831 B PHS036 7 79 3.0E-35 T 31-10-2018 IPR014418 Uncharacterised conserved protein UCP004604 TK2103 8804a587a721d7e6f96879c6c3dffeff 97 Gene3D G3DSA:3.30.2320.10 3 81 1.1E-22 T 31-10-2018 TK2103 8804a587a721d7e6f96879c6c3dffeff 97 Pfam PF08967 Domain of unknown function (DUF1884) 4 81 2.6E-32 T 31-10-2018 IPR014418 Uncharacterised conserved protein UCP004604 TK2103 8804a587a721d7e6f96879c6c3dffeff 97 SUPERFAMILY SSF111057 4 79 6.54E-29 T 31-10-2018 IPR036216 Hypothetical protein UCP004604 superfamily TK2103 8804a587a721d7e6f96879c6c3dffeff 97 PIRSF PIRSF004604 2 96 5.4E-30 T 31-10-2018 IPR014418 Uncharacterised conserved protein UCP004604 TK1489 178070fa14d4b67457501b6b27bbfdb9 237 Pfam PF00156 Phosphoribosyl transferase domain 96 222 5.8E-13 T 31-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 TK1489 178070fa14d4b67457501b6b27bbfdb9 237 SUPERFAMILY SSF47413 14 62 5.3E-5 T 31-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TK1489 178070fa14d4b67457501b6b27bbfdb9 237 Gene3D G3DSA:3.40.50.2020 61 237 1.2E-40 T 31-10-2018 TK1489 178070fa14d4b67457501b6b27bbfdb9 237 Pfam PF01381 Helix-turn-helix 14 62 3.8E-5 T 31-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TK1489 178070fa14d4b67457501b6b27bbfdb9 237 SUPERFAMILY SSF53271 77 236 6.56E-34 T 31-10-2018 IPR029057 Phosphoribosyltransferase-like TK1008 7ec3b781b091a8e50d6d9c3a1abf3211 378 SUPERFAMILY SSF56796 2 374 5.76E-98 T 31-10-2018 TK1008 7ec3b781b091a8e50d6d9c3a1abf3211 378 Gene3D G3DSA:1.20.1090.10 185 376 1.2E-55 T 31-10-2018 TK1008 7ec3b781b091a8e50d6d9c3a1abf3211 378 Gene3D G3DSA:3.40.50.1970 1 183 7.4E-42 T 31-10-2018 TK1008 7ec3b781b091a8e50d6d9c3a1abf3211 378 Pfam PF00465 Iron-containing alcohol dehydrogenase 6 367 1.3E-99 T 31-10-2018 IPR001670 Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 TK1289 cfce8f24ccf74ac53c99b7123b086b05 470 Pfam PF01554 MatE 28 187 1.4E-33 T 31-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 TK1289 cfce8f24ccf74ac53c99b7123b086b05 470 Pfam PF01554 MatE 287 426 7.7E-26 T 31-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 TK1289 cfce8f24ccf74ac53c99b7123b086b05 470 PIRSF PIRSF006603 2 470 2.8E-140 T 31-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 TK1289 cfce8f24ccf74ac53c99b7123b086b05 470 TIGRFAM TIGR00797 matE: MATE efflux family protein 28 439 5.9E-70 T 31-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 TK0262 1584dc2a370a04bd87f3dfc8f162a143 355 ProSitePatterns PS00788 Chorismate synthase signature 2. 120 136 - T 31-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 TK0262 1584dc2a370a04bd87f3dfc8f162a143 355 SUPERFAMILY SSF103263 3 352 4.45E-123 T 31-10-2018 IPR035904 Chorismate synthase AroC superfamily KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 TK0262 1584dc2a370a04bd87f3dfc8f162a143 355 PIRSF PIRSF001456 1 353 1.2E-134 T 31-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 TK0262 1584dc2a370a04bd87f3dfc8f162a143 355 ProSitePatterns PS00787 Chorismate synthase signature 1. 12 27 - T 31-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 TK0262 1584dc2a370a04bd87f3dfc8f162a143 355 TIGRFAM TIGR00033 aroC: chorismate synthase 7 349 1.1E-119 T 31-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 TK0262 1584dc2a370a04bd87f3dfc8f162a143 355 Hamap MF_00300 Chorismate synthase [aroC]. 6 352 35.547 T 31-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 TK0262 1584dc2a370a04bd87f3dfc8f162a143 355 Pfam PF01264 Chorismate synthase 7 345 6.0E-123 T 31-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 TK0262 1584dc2a370a04bd87f3dfc8f162a143 355 Gene3D G3DSA:3.60.150.10 1 354 8.4E-132 T 31-10-2018 IPR035904 Chorismate synthase AroC superfamily KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 TK1863 83c49806dcbdf557473a1eb927db400d 365 ProSitePatterns PS01261 Uncharacterized protein family UPF0020 signature. 223 234 - T 31-10-2018 IPR000241 Putative RNA methylase domain TK1863 83c49806dcbdf557473a1eb927db400d 365 Gene3D G3DSA:3.30.2130.30 1 189 1.9E-83 T 31-10-2018 TK1863 83c49806dcbdf557473a1eb927db400d 365 SUPERFAMILY SSF143437 98 181 1.26E-9 T 31-10-2018 TK1863 83c49806dcbdf557473a1eb927db400d 365 SMART SM00981 86 182 1.5E-15 T 31-10-2018 IPR004114 THUMP domain GO:0003723 TK1863 83c49806dcbdf557473a1eb927db400d 365 Gene3D G3DSA:3.40.50.150 190 365 9.4E-53 T 31-10-2018 TK1863 83c49806dcbdf557473a1eb927db400d 365 Pfam PF02926 THUMP domain 31 182 7.6E-28 T 31-10-2018 IPR004114 THUMP domain GO:0003723 TK1863 83c49806dcbdf557473a1eb927db400d 365 SUPERFAMILY SSF53335 179 359 1.24E-36 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TK1863 83c49806dcbdf557473a1eb927db400d 365 Pfam PF01170 Putative RNA methylase family UPF0020 191 358 7.4E-39 T 31-10-2018 IPR000241 Putative RNA methylase domain TK0425 97b59494e25303e831c8a38ecdc2c781 184 Pfam PF00677 Lumazine binding domain 3 75 8.5E-14 T 31-10-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TK0425 97b59494e25303e831c8a38ecdc2c781 184 Pfam PF00677 Lumazine binding domain 88 171 5.1E-22 T 31-10-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TK0425 97b59494e25303e831c8a38ecdc2c781 184 Gene3D G3DSA:2.40.30.20 90 184 1.2E-28 T 31-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TK0425 97b59494e25303e831c8a38ecdc2c781 184 PIRSF PIRSF000498 1 184 7.0E-57 T 31-10-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TK0425 97b59494e25303e831c8a38ecdc2c781 184 TIGRFAM TIGR00187 ribE: riboflavin synthase, alpha subunit 1 183 3.8E-51 T 31-10-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TK0425 97b59494e25303e831c8a38ecdc2c781 184 Gene3D G3DSA:2.40.30.20 1 76 2.2E-18 T 31-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TK0425 97b59494e25303e831c8a38ecdc2c781 184 SUPERFAMILY SSF63380 81 181 3.66E-28 T 31-10-2018 IPR017938 Riboflavin synthase-like beta-barrel TK0425 97b59494e25303e831c8a38ecdc2c781 184 SUPERFAMILY SSF63380 1 77 2.98E-16 T 31-10-2018 IPR017938 Riboflavin synthase-like beta-barrel TK0011 369ace83fcd56f0676de146aaf1b4600 140 PIRSF PIRSF004681 2 133 6.6E-39 T 31-10-2018 IPR001602 Uncharacterised protein family UPF0047 TK0011 369ace83fcd56f0676de146aaf1b4600 140 Pfam PF01894 Uncharacterised protein family UPF0047 17 130 2.8E-37 T 31-10-2018 IPR001602 Uncharacterised protein family UPF0047 TK0011 369ace83fcd56f0676de146aaf1b4600 140 SUPERFAMILY SSF111038 2 131 3.79E-41 T 31-10-2018 IPR035917 YjbQ-like superfamily TK0011 369ace83fcd56f0676de146aaf1b4600 140 TIGRFAM TIGR00149 TIGR00149_YjbQ: secondary thiamine-phosphate synthase enzyme 4 131 1.3E-40 T 31-10-2018 IPR001602 Uncharacterised protein family UPF0047 TK0011 369ace83fcd56f0676de146aaf1b4600 140 Gene3D G3DSA:2.60.120.460 1 132 5.2E-49 T 31-10-2018 IPR035917 YjbQ-like superfamily TK0810 23969b8636ac4c415c8b38737404420d 1000 Gene3D G3DSA:3.40.50.12610 509 639 5.0E-34 T 31-10-2018 TK0810 23969b8636ac4c415c8b38737404420d 1000 Gene3D G3DSA:2.60.40.3030 858 990 6.1E-115 T 31-10-2018 TK0810 23969b8636ac4c415c8b38737404420d 1000 Gene3D G3DSA:2.60.40.3020 748 997 6.1E-115 T 31-10-2018 TK0810 23969b8636ac4c415c8b38737404420d 1000 Pfam PF02516 Oligosaccharyl transferase STT3 subunit 79 537 3.3E-11 T 31-10-2018 IPR003674 Oligosaccharyl transferase, STT3 subunit GO:0004576|GO:0006486|GO:0016020 TK0925 5585f7759f882f92b1563ddd80fb9439 574 Pfam PF01409 tRNA synthetases class II core domain (F) 362 561 2.0E-4 T 31-10-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 TK0925 5585f7759f882f92b1563ddd80fb9439 574 Pfam PF03484 tRNA synthetase B5 domain 284 348 1.3E-13 T 31-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 TK0925 5585f7759f882f92b1563ddd80fb9439 574 Gene3D G3DSA:3.30.56.10 1 80 8.7E-23 T 31-10-2018 TK0925 5585f7759f882f92b1563ddd80fb9439 574 SMART SM00874 280 348 1.2E-16 T 31-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 TK0925 5585f7759f882f92b1563ddd80fb9439 574 Gene3D G3DSA:3.30.56.10 279 348 2.1E-27 T 31-10-2018 TK0925 5585f7759f882f92b1563ddd80fb9439 574 Hamap MF_00284 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 566 36.029 T 31-10-2018 IPR022918 Phenylalanine-tRNA ligase beta chain 2, bacterial/archaeal GO:0004826 KEGG: 00970+6.1.1.20 TK0925 5585f7759f882f92b1563ddd80fb9439 574 SUPERFAMILY SSF46955 5 81 1.19E-8 T 31-10-2018 IPR009061 Putative DNA-binding domain superfamily TK0925 5585f7759f882f92b1563ddd80fb9439 574 SMART SM00873 100 259 2.0E-22 T 31-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 TK0925 5585f7759f882f92b1563ddd80fb9439 574 SUPERFAMILY SSF46955 281 352 1.19E-15 T 31-10-2018 IPR009061 Putative DNA-binding domain superfamily TK0925 5585f7759f882f92b1563ddd80fb9439 574 Pfam PF03483 B3/4 domain 119 243 1.4E-16 T 31-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 TK0925 5585f7759f882f92b1563ddd80fb9439 574 SUPERFAMILY SSF56037 142 259 1.05E-6 T 31-10-2018 TK0925 5585f7759f882f92b1563ddd80fb9439 574 Gene3D G3DSA:3.50.40.10 81 278 1.6E-74 T 31-10-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 KEGG: 00970+6.1.1.20 TK0925 5585f7759f882f92b1563ddd80fb9439 574 TIGRFAM TIGR00471 pheT_arch: phenylalanine--tRNA ligase, beta subunit 1 563 3.8E-177 T 31-10-2018 IPR004531 Phenylalanyl-tRNA synthetase, class IIc, beta subunit, archae/euk cytosolic GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 TK0925 5585f7759f882f92b1563ddd80fb9439 574 SUPERFAMILY SSF55681 345 568 5.3E-44 T 31-10-2018 TK0925 5585f7759f882f92b1563ddd80fb9439 574 Gene3D G3DSA:3.30.930.10 365 570 3.7E-52 T 31-10-2018 TK1591 7b6b40bd7182a0aa62afa7857f6a7b05 184 SUPERFAMILY SSF46785 62 174 8.62E-6 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TK1591 7b6b40bd7182a0aa62afa7857f6a7b05 184 Gene3D G3DSA:1.10.10.60 58 86 2.8E-6 T 31-10-2018 TK1591 7b6b40bd7182a0aa62afa7857f6a7b05 184 TIGRFAM TIGR03879 near_KaiC_dom: probable regulatory domain 32 104 2.6E-26 T 31-10-2018 IPR022285 Conserved hypothetical protein CHP03879, regulatory domain, putative TK1945 5c97de842593da4535d6cd676f2c2922 140 Gene3D G3DSA:3.40.50.1010 9 138 1.0E-29 T 31-10-2018 TK1945 5c97de842593da4535d6cd676f2c2922 140 SMART SM00670 9 115 7.7E-6 T 31-10-2018 IPR002716 PIN domain TK1945 5c97de842593da4535d6cd676f2c2922 140 SUPERFAMILY SSF88723 9 132 1.28E-23 T 31-10-2018 IPR029060 PIN-like domain superfamily TK1945 5c97de842593da4535d6cd676f2c2922 140 Pfam PF04900 Fcf1 35 132 7.7E-7 T 31-10-2018 IPR006984 rRNA-processing protein Fcf1/Utp23 GO:0032040 TK0293 96685202443301ee301206f0cbfb9a08 231 SUPERFAMILY SSF63999 51 144 5.36E-10 T 31-10-2018 IPR036759 Thiamin pyrophosphokinase, catalytic domain superfamily GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 TK0293 96685202443301ee301206f0cbfb9a08 231 Hamap MF_02131 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase [mptE]. 7 224 36.728 T 31-10-2018 IPR027510 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, MptE GO:0003848|GO:0005524 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 TK0293 96685202443301ee301206f0cbfb9a08 231 Pfam PF01973 Protein of unknown function DUF115 49 186 1.1E-28 T 31-10-2018 IPR002826 6-hydroxymethylpterin diphosphokinase MptE-like TK2032 72b22d839e52bde8e92da995547686b4 104 SUPERFAMILY SSF54913 3 100 9.27E-32 T 31-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta TK2032 72b22d839e52bde8e92da995547686b4 104 Gene3D G3DSA:3.30.70.120 1 103 2.5E-35 T 31-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal TK2032 72b22d839e52bde8e92da995547686b4 104 Pfam PF03091 CutA1 divalent ion tolerance protein 4 99 4.5E-30 T 31-10-2018 IPR004323 Divalent ion tolerance protein, CutA GO:0010038 TK1608 97b1fbde2ef9f9c12b7470762c73e8f0 237 Gene3D G3DSA:3.40.50.11570 11 225 9.8E-61 T 31-10-2018 TK1608 97b1fbde2ef9f9c12b7470762c73e8f0 237 Pfam PF03192 Pyrococcus protein of unknown function, DUF257 15 221 5.5E-78 T 31-10-2018 IPR005489 Protein of unknown function DUF257 TK1170 7ca6ffafefe543d12f4bc9a36facdd89 626 SUPERFAMILY SSF52954 504 606 2.11E-31 T 31-10-2018 TK1170 7ca6ffafefe543d12f4bc9a36facdd89 626 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 27 603 6.8E-174 T 31-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 TK1170 7ca6ffafefe543d12f4bc9a36facdd89 626 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 35 602 29.043 T 31-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 TK1170 7ca6ffafefe543d12f4bc9a36facdd89 626 Gene3D G3DSA:3.30.930.10 203 494 1.5E-63 T 31-10-2018 TK1170 7ca6ffafefe543d12f4bc9a36facdd89 626 Gene3D G3DSA:3.40.50.800 504 607 1.8E-33 T 31-10-2018 IPR036621 Anticodon-binding domain superfamily TK1170 7ca6ffafefe543d12f4bc9a36facdd89 626 Pfam PF08915 Archaea-specific editing domain of threonyl-tRNA synthetase 1 139 3.0E-56 T 31-10-2018 IPR015011 Threonyl-tRNA synthetase, editing domain, archaea GO:0004829|GO:0005524|GO:0005737|GO:0008270 KEGG: 00970+6.1.1.3 TK1170 7ca6ffafefe543d12f4bc9a36facdd89 626 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 288 492 3.8E-19 T 31-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 TK1170 7ca6ffafefe543d12f4bc9a36facdd89 626 Gene3D G3DSA:3.50.80.10 1 139 1.4E-57 T 31-10-2018 IPR023509 D-aminoacyl-tRNA deacylase-like superfamily TK1170 7ca6ffafefe543d12f4bc9a36facdd89 626 PRINTS PR01047 Threonyl-tRNA synthetase signature 428 456 1.6E-32 T 31-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 TK1170 7ca6ffafefe543d12f4bc9a36facdd89 626 PRINTS PR01047 Threonyl-tRNA synthetase signature 506 518 1.6E-32 T 31-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 TK1170 7ca6ffafefe543d12f4bc9a36facdd89 626 PRINTS PR01047 Threonyl-tRNA synthetase signature 471 484 1.6E-32 T 31-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 TK1170 7ca6ffafefe543d12f4bc9a36facdd89 626 PRINTS PR01047 Threonyl-tRNA synthetase signature 294 322 1.6E-32 T 31-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 TK1170 7ca6ffafefe543d12f4bc9a36facdd89 626 PRINTS PR01047 Threonyl-tRNA synthetase signature 328 351 1.6E-32 T 31-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 TK1170 7ca6ffafefe543d12f4bc9a36facdd89 626 SUPERFAMILY SSF55681 207 489 8.85E-58 T 31-10-2018 TK1170 7ca6ffafefe543d12f4bc9a36facdd89 626 Pfam PF03129 Anticodon binding domain 513 601 1.9E-25 T 31-10-2018 IPR004154 Anticodon-binding TK1170 7ca6ffafefe543d12f4bc9a36facdd89 626 ProDom PD016189 SYNTHETASE LIGASE THREONYL-TRNA AMINOACYL-TRNA NUCLEOTIDE-BINDING BIOSYNTHESIS ATP-BINDING ZINC METAL-BINDING THRRS 1 139 8.0E-74 T 31-10-2018 IPR015011 Threonyl-tRNA synthetase, editing domain, archaea GO:0004829|GO:0005524|GO:0005737|GO:0008270 KEGG: 00970+6.1.1.3 TK0072 d5cda68320b6a615717fa6a9e2bfc972 633 Gene3D G3DSA:1.10.599.10 239 622 3.2E-133 T 31-10-2018 IPR013985 Aldehyde ferredoxin oxidoreductase, domain 3 GO:0016625|GO:0051536|GO:0055114 KEGG: 00030+1.2.7.5 TK0072 d5cda68320b6a615717fa6a9e2bfc972 633 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 220 622 4.7E-127 T 31-10-2018 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 TK0072 d5cda68320b6a615717fa6a9e2bfc972 633 Gene3D G3DSA:3.60.9.10 5 211 6.9E-71 T 31-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily TK0072 d5cda68320b6a615717fa6a9e2bfc972 633 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 9 205 5.4E-66 T 31-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 TK0072 d5cda68320b6a615717fa6a9e2bfc972 633 SUPERFAMILY SSF56228 6 209 7.98E-63 T 31-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily TK0072 d5cda68320b6a615717fa6a9e2bfc972 633 Gene3D G3DSA:1.10.569.10 241 444 3.2E-133 T 31-10-2018 IPR013984 Aldehyde ferredoxin oxidoreductase, domain 2 TK0072 d5cda68320b6a615717fa6a9e2bfc972 633 SMART SM00790 7 207 4.0E-106 T 31-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 TK0072 d5cda68320b6a615717fa6a9e2bfc972 633 SUPERFAMILY SSF48310 213 629 5.62E-120 T 31-10-2018 IPR036021 Aldehyde ferredoxin oxidoreductase-like, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 TK1860 e8b4b2261680af391588efe28f488f19 416 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 232 407 9.1E-9 T 31-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TK1860 e8b4b2261680af391588efe28f488f19 416 SUPERFAMILY SSF161098 209 401 1.83E-14 T 31-10-2018 IPR035906 MetI-like superfamily TK1860 e8b4b2261680af391588efe28f488f19 416 Gene3D G3DSA:1.10.3720.10 203 414 5.3E-12 T 31-10-2018 IPR035906 MetI-like superfamily TK0328 8d400ebb97ded6253f87b31df5d3f1f5 144 SUPERFAMILY SSF52242 5 133 3.14E-49 T 31-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 TK0328 8d400ebb97ded6253f87b31df5d3f1f5 144 Pfam PF02310 B12 binding domain 8 121 1.6E-24 T 31-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 TK0328 8d400ebb97ded6253f87b31df5d3f1f5 144 Gene3D G3DSA:3.40.50.280 1 144 7.4E-58 T 31-10-2018 TK0328 8d400ebb97ded6253f87b31df5d3f1f5 144 TIGRFAM TIGR00640 acid_CoA_mut_C: methylmalonyl-CoA mutase C-terminal domain 6 138 5.6E-61 T 31-10-2018 IPR006159 Methylmalonyl-CoA mutase, C-terminal GO:0016853 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 TK1421 c339a5d6293e46f02585d077f0818cfe 373 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 31 355 6.2E-137 T 31-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 TK1421 c339a5d6293e46f02585d077f0818cfe 373 ProSitePatterns PS01134 FtsZ protein signature 1. 74 108 - T 31-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 TK1421 c339a5d6293e46f02585d077f0818cfe 373 Gene3D G3DSA:3.30.1330.20 254 362 3.8E-35 T 31-10-2018 IPR037103 Tubulin/FtsZ, C-terminal domain superfamily Reactome: R-HSA-380320 TK1421 c339a5d6293e46f02585d077f0818cfe 373 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 39 371 38.452 T 31-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 TK1421 c339a5d6293e46f02585d077f0818cfe 373 SMART SM00864 43 234 1.1E-108 T 31-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TK1421 c339a5d6293e46f02585d077f0818cfe 373 SUPERFAMILY SSF52490 38 235 3.53E-70 T 31-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 TK1421 c339a5d6293e46f02585d077f0818cfe 373 SUPERFAMILY SSF55307 236 348 4.12E-38 T 31-10-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 TK1421 c339a5d6293e46f02585d077f0818cfe 373 SMART SM00865 236 352 1.6E-49 T 31-10-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-380320 TK1421 c339a5d6293e46f02585d077f0818cfe 373 PRINTS PR00423 Cell division protein FtsZ signature 218 240 4.8E-44 T 31-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TK1421 c339a5d6293e46f02585d077f0818cfe 373 PRINTS PR00423 Cell division protein FtsZ signature 128 148 4.8E-44 T 31-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TK1421 c339a5d6293e46f02585d077f0818cfe 373 PRINTS PR00423 Cell division protein FtsZ signature 156 177 4.8E-44 T 31-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TK1421 c339a5d6293e46f02585d077f0818cfe 373 PRINTS PR00423 Cell division protein FtsZ signature 241 262 4.8E-44 T 31-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TK1421 c339a5d6293e46f02585d077f0818cfe 373 Pfam PF12327 FtsZ family, C-terminal domain 251 343 1.9E-31 T 31-10-2018 IPR024757 Cell division protein FtsZ, C-terminal TK1421 c339a5d6293e46f02585d077f0818cfe 373 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 43 203 7.8E-47 T 31-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TK1421 c339a5d6293e46f02585d077f0818cfe 373 ProSitePatterns PS01135 FtsZ protein signature 2. 127 148 - T 31-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 TK1421 c339a5d6293e46f02585d077f0818cfe 373 Gene3D G3DSA:3.40.50.1440 35 249 2.0E-83 T 31-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 TK1183 3eaffe18f6b1110159793b5a5481df17 295 SUPERFAMILY SSF55920 3 295 9.55E-67 T 31-10-2018 IPR036005 Creatinase/aminopeptidase-like TK1183 3eaffe18f6b1110159793b5a5481df17 295 PRINTS PR00599 Methionine aminopeptidase-1 signature 53 66 7.9E-17 T 31-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 TK1183 3eaffe18f6b1110159793b5a5481df17 295 PRINTS PR00599 Methionine aminopeptidase-1 signature 177 189 7.9E-17 T 31-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 TK1183 3eaffe18f6b1110159793b5a5481df17 295 PRINTS PR00599 Methionine aminopeptidase-1 signature 78 94 7.9E-17 T 31-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 TK1183 3eaffe18f6b1110159793b5a5481df17 295 PRINTS PR00599 Methionine aminopeptidase-1 signature 145 157 7.9E-17 T 31-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 TK1183 3eaffe18f6b1110159793b5a5481df17 295 SUPERFAMILY SSF46785 196 271 2.72E-18 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TK1183 3eaffe18f6b1110159793b5a5481df17 295 Gene3D G3DSA:1.10.10.10 196 272 1.4E-107 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TK1183 3eaffe18f6b1110159793b5a5481df17 295 ProSitePatterns PS01202 Methionine aminopeptidase subfamily 2 signature. 78 94 - T 31-10-2018 IPR018349 Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site MetaCyc: PWY-7799|MetaCyc: PWY-7800 TK1183 3eaffe18f6b1110159793b5a5481df17 295 Gene3D G3DSA:3.90.230.10 9 286 1.4E-107 T 31-10-2018 TK1183 3eaffe18f6b1110159793b5a5481df17 295 Hamap MF_01975 Methionine aminopeptidase [map]. 4 295 47.244 T 31-10-2018 IPR028595 Methionine aminopeptidase, archaeal GO:0004177|GO:0006508 MetaCyc: PWY-7799|MetaCyc: PWY-7800 TK1183 3eaffe18f6b1110159793b5a5481df17 295 TIGRFAM TIGR00501 met_pdase_II: methionine aminopeptidase, type II 2 295 1.2E-117 T 31-10-2018 IPR002468 Peptidase M24A, methionine aminopeptidase, subfamily 2 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800|Reactome: R-HSA-2514859 TK1183 3eaffe18f6b1110159793b5a5481df17 295 Pfam PF00557 Metallopeptidase family M24 7 287 4.1E-45 T 31-10-2018 IPR000994 Peptidase M24 TK2268 c04a761481efd89ae4018020e0017b57 392 Gene3D G3DSA:3.40.640.10 65 284 2.5E-133 T 31-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TK2268 c04a761481efd89ae4018020e0017b57 392 SUPERFAMILY SSF53383 10 391 6.92E-124 T 31-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TK2268 c04a761481efd89ae4018020e0017b57 392 Gene3D G3DSA:3.90.1150.10 34 384 2.5E-133 T 31-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TK2268 c04a761481efd89ae4018020e0017b57 392 Pfam PF00155 Aminotransferase class I and II 34 384 5.1E-73 T 31-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 TK2268 c04a761481efd89ae4018020e0017b57 392 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 234 247 - T 31-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 TK1979 56b5aee867d486d8bdbc4953891d7432 105 Pfam PF14697 4Fe-4S dicluster domain 47 100 8.8E-11 T 31-10-2018 TK1979 56b5aee867d486d8bdbc4953891d7432 105 TIGRFAM TIGR02179 PorD_KorD: 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate family 32 104 1.2E-33 T 31-10-2018 IPR011898 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate GO:0016625|GO:0051539 TK1979 56b5aee867d486d8bdbc4953891d7432 105 SUPERFAMILY SSF54862 32 103 5.76E-25 T 31-10-2018 TK1979 56b5aee867d486d8bdbc4953891d7432 105 Gene3D G3DSA:3.30.70.20 32 72 3.2E-6 T 31-10-2018 TK1979 56b5aee867d486d8bdbc4953891d7432 105 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 83 94 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TK1979 56b5aee867d486d8bdbc4953891d7432 105 Gene3D G3DSA:3.30.70.20 73 105 6.0E-9 T 31-10-2018 TK0509 769ce5bf1d3d152100fda27910bf31f4 185 Gene3D G3DSA:3.40.50.1950 1 182 7.5E-76 T 31-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 TK0509 769ce5bf1d3d152100fda27910bf31f4 185 TIGRFAM TIGR00421 ubiX_pad: polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylases 2 175 1.4E-72 T 31-10-2018 IPR004507 Flavin prenyltransferase UbiX-like TK0509 769ce5bf1d3d152100fda27910bf31f4 185 Pfam PF02441 Flavoprotein 1 156 7.7E-29 T 31-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 TK0509 769ce5bf1d3d152100fda27910bf31f4 185 Hamap MF_01984 Flavin prenyltransferase UbiX [ubiX]. 1 177 37.987 T 31-10-2018 IPR004507 Flavin prenyltransferase UbiX-like TK0509 769ce5bf1d3d152100fda27910bf31f4 185 SUPERFAMILY SSF52507 1 176 3.27E-60 T 31-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 TK2009 dbe20363c621f579d52d9e642f4865dd 297 Gene3D G3DSA:3.30.70.1350 205 283 2.3E-9 T 31-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 TK2009 dbe20363c621f579d52d9e642f4865dd 297 SUPERFAMILY SSF161111 10 205 3.27E-58 T 31-10-2018 IPR027469 Cation efflux transmembrane domain superfamily TK2009 dbe20363c621f579d52d9e642f4865dd 297 Gene3D G3DSA:1.20.1510.10 10 204 1.0E-48 T 31-10-2018 IPR027469 Cation efflux transmembrane domain superfamily TK2009 dbe20363c621f579d52d9e642f4865dd 297 Pfam PF16916 Dimerisation domain of Zinc Transporter 209 281 5.4E-12 T 31-10-2018 IPR027470 Cation efflux protein, cytoplasmic domain TK2009 dbe20363c621f579d52d9e642f4865dd 297 SUPERFAMILY SSF160240 206 281 2.62E-16 T 31-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 TK2009 dbe20363c621f579d52d9e642f4865dd 297 Pfam PF01545 Cation efflux family 14 204 1.2E-50 T 31-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 TK2009 dbe20363c621f579d52d9e642f4865dd 297 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 12 282 1.7E-93 T 31-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 TK0285 d8f09e1a58a546aaa4692e7be50a205f 35 Gene3D G3DSA:3.40.50.300 1 35 2.9E-6 T 31-10-2018 TK1027 461def0461168d8caffccd5af6d011ca 160 SUPERFAMILY SSF88723 8 145 9.25E-14 T 31-10-2018 IPR029060 PIN-like domain superfamily TK1027 461def0461168d8caffccd5af6d011ca 160 Pfam PF01850 PIN domain 9 129 5.1E-11 T 31-10-2018 IPR002716 PIN domain TK1027 461def0461168d8caffccd5af6d011ca 160 Gene3D G3DSA:3.40.50.1010 7 139 1.0E-8 T 31-10-2018 TK1815 43b3b9a39c0aae60f4439c49413e8241 80 Gene3D G3DSA:1.10.1220.10 11 56 8.1E-8 T 31-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 TK1815 43b3b9a39c0aae60f4439c49413e8241 80 SUPERFAMILY SSF47598 6 47 5.06E-11 T 31-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 TK1815 43b3b9a39c0aae60f4439c49413e8241 80 Pfam PF01402 Ribbon-helix-helix protein, copG family 7 44 2.7E-10 T 31-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 TK0434 26dc758cf7277eddb116cc913bb30b1d 251 PRINTS PR00419 Adrenodoxin reductase family signature 48 61 1.0E-6 T 31-10-2018 TK0434 26dc758cf7277eddb116cc913bb30b1d 251 PRINTS PR00419 Adrenodoxin reductase family signature 25 47 1.0E-6 T 31-10-2018 TK0434 26dc758cf7277eddb116cc913bb30b1d 251 Gene3D G3DSA:3.50.50.60 1 251 4.2E-99 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TK0434 26dc758cf7277eddb116cc913bb30b1d 251 TIGRFAM TIGR00292 TIGR00292: thiazole biosynthesis enzyme 3 249 8.6E-92 T 31-10-2018 IPR002922 Thiazole biosynthetic enzyme Thi4 family TK0434 26dc758cf7277eddb116cc913bb30b1d 251 Pfam PF01946 Thi4 family 7 231 1.3E-78 T 31-10-2018 TK0434 26dc758cf7277eddb116cc913bb30b1d 251 Hamap MF_00304 Thiamine thiazole synthase [thi4]. 1 250 43.905 T 31-10-2018 IPR022828 Thiazole biosynthetic enzyme, prokaryotic TK0434 26dc758cf7277eddb116cc913bb30b1d 251 SUPERFAMILY SSF51905 2 242 7.69E-45 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TK2266 7c424ae05a6d2f5a980f6d45b4351b2a 399 Pfam PF07690 Major Facilitator Superfamily 22 355 1.8E-20 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TK2266 7c424ae05a6d2f5a980f6d45b4351b2a 399 Gene3D G3DSA:1.20.1250.20 194 392 2.3E-7 T 31-10-2018 TK2266 7c424ae05a6d2f5a980f6d45b4351b2a 399 Gene3D G3DSA:1.20.1250.20 2 186 7.6E-16 T 31-10-2018 TK2266 7c424ae05a6d2f5a980f6d45b4351b2a 399 SUPERFAMILY SSF103473 4 388 6.15E-37 T 31-10-2018 IPR036259 MFS transporter superfamily TK0058 cdb03fa4afc0f02e2a06b5231a7c4922 234 Pfam PF13419 Haloacid dehalogenase-like hydrolase 4 200 2.1E-30 T 31-10-2018 TK0058 cdb03fa4afc0f02e2a06b5231a7c4922 234 Gene3D G3DSA:3.40.50.1000 3 222 3.0E-63 T 31-10-2018 IPR023214 HAD superfamily TK0058 cdb03fa4afc0f02e2a06b5231a7c4922 234 SUPERFAMILY SSF56784 1 230 4.67E-51 T 31-10-2018 IPR036412 HAD-like superfamily TK0058 cdb03fa4afc0f02e2a06b5231a7c4922 234 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 1 12 1.1E-12 T 31-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TK0058 cdb03fa4afc0f02e2a06b5231a7c4922 234 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 114 127 1.1E-12 T 31-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TK0058 cdb03fa4afc0f02e2a06b5231a7c4922 234 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 145 161 1.1E-12 T 31-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TK0058 cdb03fa4afc0f02e2a06b5231a7c4922 234 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 163 183 1.1E-12 T 31-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TK0058 cdb03fa4afc0f02e2a06b5231a7c4922 234 Gene3D G3DSA:1.10.150.240 15 100 3.0E-63 T 31-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 TK0058 cdb03fa4afc0f02e2a06b5231a7c4922 234 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 102 201 1.4E-10 T 31-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TK0058 cdb03fa4afc0f02e2a06b5231a7c4922 234 TIGRFAM TIGR02253 CTE7: HAD hydrolase, TIGR02253 family 2 226 3.9E-61 T 31-10-2018 IPR011950 HAD-superfamily hydrolase, subfamily IA, CTE7 GO:0016787 Reactome: R-HSA-4085001 TK0058 cdb03fa4afc0f02e2a06b5231a7c4922 234 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 99 196 3.8E-13 T 31-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TK1143 6201d17591fae2a8a50e0b78d3a93aa4 156 SUPERFAMILY SSF46785 10 138 2.89E-26 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TK1143 6201d17591fae2a8a50e0b78d3a93aa4 156 Pfam PF03551 Transcriptional regulator PadR-like family 14 84 8.2E-19 T 31-10-2018 IPR005149 Transcription regulator PadR, N-terminal TK1143 6201d17591fae2a8a50e0b78d3a93aa4 156 Gene3D G3DSA:1.10.10.10 1 104 1.0E-26 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TK2096 533b305e06c16e3005ef3c005d60b5ec 162 Pfam PF02915 Rubrerythrin 21 157 1.8E-16 T 31-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 TK2096 533b305e06c16e3005ef3c005d60b5ec 162 SUPERFAMILY SSF47240 17 161 1.68E-25 T 31-10-2018 IPR009078 Ferritin-like superfamily TK2096 533b305e06c16e3005ef3c005d60b5ec 162 Gene3D G3DSA:1.20.1260.10 11 160 1.6E-31 T 31-10-2018 IPR012347 Ferritin-like TK0236 183c198b91aa62650311da36af86a2bd 312 SUPERFAMILY SSF50998 89 302 1.23E-6 T 31-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily TK1573 891d34403abeaa9e28327b52402da6d4 465 Gene3D G3DSA:3.40.50.300 1 168 4.4E-27 T 31-10-2018 TK1573 891d34403abeaa9e28327b52402da6d4 465 Pfam PF01637 ATPase domain predominantly from Archaea 3 202 6.5E-15 T 31-10-2018 IPR011579 ATPase domain GO:0005524 TK1573 891d34403abeaa9e28327b52402da6d4 465 Pfam PF03008 Archaea bacterial proteins of unknown function 315 415 1.4E-24 T 31-10-2018 IPR004256 Domain of unknown function DUF234, DEXX-box ATPase C-terminal TK1573 891d34403abeaa9e28327b52402da6d4 465 SUPERFAMILY SSF52540 1 227 1.3E-31 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK1593 d1106aedc40e9ad7ceb9a4f1d49c9b83 301 Hamap MF_01464_A Protein-export membrane protein SecF [secF]. 27 300 25.728 T 31-10-2018 IPR024921 Protein-export membrane protein SecF, archaeal GO:0016021|GO:0065002 TK1593 d1106aedc40e9ad7ceb9a4f1d49c9b83 301 SUPERFAMILY SSF82866 116 293 2.22E-24 T 31-10-2018 TK1593 d1106aedc40e9ad7ceb9a4f1d49c9b83 301 Pfam PF02355 Protein export membrane protein 131 295 1.3E-31 T 31-10-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial TK1593 d1106aedc40e9ad7ceb9a4f1d49c9b83 301 Gene3D G3DSA:1.20.1640.10 122 298 5.5E-14 T 31-10-2018 TK2227 39c2487cb0a2a600e091d66bbc264819 471 Pfam PF10150 Ribonuclease E/G family 152 262 5.5E-11 T 31-10-2018 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 TK2227 39c2487cb0a2a600e091d66bbc264819 471 Hamap MF_01910 RNA-binding protein AU-1 [aubA]. 7 471 35.563 T 31-10-2018 IPR016730 RNA-binding AU-1 GO:0003723 TK2227 39c2487cb0a2a600e091d66bbc264819 471 Gene3D G3DSA:2.40.380.10 374 471 3.5E-11 T 31-10-2018 IPR035930 FomD-like superfamily TK2227 39c2487cb0a2a600e091d66bbc264819 471 SMART SM00316 92 152 0.0038 T 31-10-2018 IPR022967 RNA-binding domain, S1 TK2227 39c2487cb0a2a600e091d66bbc264819 471 Pfam PF04167 Protein of unknown function (DUF402) 377 443 4.9E-15 T 31-10-2018 IPR007295 Domain of unknown function DUF402 TK2227 39c2487cb0a2a600e091d66bbc264819 471 PIRSF PIRSF018644 5 471 1.7E-203 T 31-10-2018 IPR016730 RNA-binding AU-1 GO:0003723 TK2227 39c2487cb0a2a600e091d66bbc264819 471 SUPERFAMILY SSF159234 319 469 7.85E-32 T 31-10-2018 IPR035930 FomD-like superfamily TK1505 a86a68c430ac4342178ce7a1f7697dfa 180 SMART SM00363 103 165 6.2E-15 T 31-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1505 a86a68c430ac4342178ce7a1f7697dfa 180 ProSitePatterns PS00632 Ribosomal protein S4 signature. 101 125 - T 31-10-2018 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1505 a86a68c430ac4342178ce7a1f7697dfa 180 Hamap MF_01306_A 30S ribosomal protein S4 [rpsD]. 1 156 34.459 T 31-10-2018 IPR022802 Ribosomal protein S4, archaeal GO:0006412|GO:0019843 TK1505 a86a68c430ac4342178ce7a1f7697dfa 180 SMART SM01390 5 102 1.3E-10 T 31-10-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 TK1505 a86a68c430ac4342178ce7a1f7697dfa 180 Gene3D G3DSA:3.10.290.10 102 176 1.5E-17 T 31-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 TK1505 a86a68c430ac4342178ce7a1f7697dfa 180 TIGRFAM TIGR01018 uS4_arch: ribosomal protein uS4 1 161 2.6E-75 T 31-10-2018 IPR005710 Ribosomal protein S4/S9, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1505 a86a68c430ac4342178ce7a1f7697dfa 180 SUPERFAMILY SSF55174 9 160 3.19E-34 T 31-10-2018 TK1505 a86a68c430ac4342178ce7a1f7697dfa 180 Pfam PF01479 S4 domain 103 148 4.2E-17 T 31-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK0291 32cde5d0b757ef93d44b9f68d5a08afc 182 Pfam PF13526 Protein of unknown function (DUF4125) 6 173 2.0E-45 T 31-10-2018 IPR025191 Protein of unknown function DUF4125 TK0349 27e01e6652905bb22a898352b7112d78 259 PIRSF PIRSF003092 1 259 1.6E-65 T 31-10-2018 IPR025501 ATP binding protein MinD TK0349 27e01e6652905bb22a898352b7112d78 259 Gene3D G3DSA:3.40.50.300 4 233 3.8E-66 T 31-10-2018 TK0349 27e01e6652905bb22a898352b7112d78 259 TIGRFAM TIGR01969 minD_arch: cell division ATPase MinD 4 251 3.1E-117 T 31-10-2018 IPR010224 ATP binding protein MinD, archaea TK0349 27e01e6652905bb22a898352b7112d78 259 SMART SM00382 3 163 0.0011 T 31-10-2018 IPR003593 AAA+ ATPase domain TK0349 27e01e6652905bb22a898352b7112d78 259 SUPERFAMILY SSF52540 3 236 1.15E-57 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK0349 27e01e6652905bb22a898352b7112d78 259 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 6 212 8.1E-25 T 31-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain TK1604 7644bb4a865386f9d04d46a0274dd951 214 Hamap MF_00271 V-type ATP synthase subunit D [atpD]. 4 211 25.674 T 31-10-2018 IPR002699 ATPase, V1 complex, subunit D GO:0042626 Reactome: R-HSA-1222556|Reactome: R-HSA-6798695|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TK1604 7644bb4a865386f9d04d46a0274dd951 214 Pfam PF01813 ATP synthase subunit D 13 206 2.6E-62 T 31-10-2018 IPR002699 ATPase, V1 complex, subunit D GO:0042626 Reactome: R-HSA-1222556|Reactome: R-HSA-6798695|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TK1604 7644bb4a865386f9d04d46a0274dd951 214 TIGRFAM TIGR00309 V_ATPase_subD: V-type ATPase, D subunit 6 209 1.1E-69 T 31-10-2018 IPR002699 ATPase, V1 complex, subunit D GO:0042626 Reactome: R-HSA-1222556|Reactome: R-HSA-6798695|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TK1329 454109c7c9c4667a7d7fbe66a1953d9d 204 Gene3D G3DSA:3.40.50.11570 5 202 5.1E-15 T 31-10-2018 TK1329 454109c7c9c4667a7d7fbe66a1953d9d 204 Pfam PF03192 Pyrococcus protein of unknown function, DUF257 10 192 7.3E-14 T 31-10-2018 IPR005489 Protein of unknown function DUF257 TK1545 b114875b9b180f520b374a3fbcf979cd 380 Gene3D G3DSA:3.30.70.3360 314 362 1.2E-37 T 31-10-2018 TK1545 b114875b9b180f520b374a3fbcf979cd 380 Gene3D G3DSA:3.30.470.30 96 197 2.1E-69 T 31-10-2018 TK1545 b114875b9b180f520b374a3fbcf979cd 380 SUPERFAMILY SSF56091 64 255 1.19E-37 T 31-10-2018 TK1545 b114875b9b180f520b374a3fbcf979cd 380 PRINTS PR01048 Hypothetical protein Y414 family signature 355 375 2.0E-54 T 31-10-2018 IPR001072 RNA ligase, Pab1020 family TK1545 b114875b9b180f520b374a3fbcf979cd 380 PRINTS PR01048 Hypothetical protein Y414 family signature 87 100 2.0E-54 T 31-10-2018 IPR001072 RNA ligase, Pab1020 family TK1545 b114875b9b180f520b374a3fbcf979cd 380 PRINTS PR01048 Hypothetical protein Y414 family signature 42 56 2.0E-54 T 31-10-2018 IPR001072 RNA ligase, Pab1020 family TK1545 b114875b9b180f520b374a3fbcf979cd 380 PRINTS PR01048 Hypothetical protein Y414 family signature 138 153 2.0E-54 T 31-10-2018 IPR001072 RNA ligase, Pab1020 family TK1545 b114875b9b180f520b374a3fbcf979cd 380 PRINTS PR01048 Hypothetical protein Y414 family signature 260 278 2.0E-54 T 31-10-2018 IPR001072 RNA ligase, Pab1020 family TK1545 b114875b9b180f520b374a3fbcf979cd 380 PRINTS PR01048 Hypothetical protein Y414 family signature 164 185 2.0E-54 T 31-10-2018 IPR001072 RNA ligase, Pab1020 family TK1545 b114875b9b180f520b374a3fbcf979cd 380 PRINTS PR01048 Hypothetical protein Y414 family signature 108 123 2.0E-54 T 31-10-2018 IPR001072 RNA ligase, Pab1020 family TK1545 b114875b9b180f520b374a3fbcf979cd 380 PRINTS PR01048 Hypothetical protein Y414 family signature 219 232 2.0E-54 T 31-10-2018 IPR001072 RNA ligase, Pab1020 family TK1545 b114875b9b180f520b374a3fbcf979cd 380 PRINTS PR01048 Hypothetical protein Y414 family signature 291 305 2.0E-54 T 31-10-2018 IPR001072 RNA ligase, Pab1020 family TK1545 b114875b9b180f520b374a3fbcf979cd 380 PRINTS PR01048 Hypothetical protein Y414 family signature 64 82 2.0E-54 T 31-10-2018 IPR001072 RNA ligase, Pab1020 family TK1545 b114875b9b180f520b374a3fbcf979cd 380 Gene3D G3DSA:3.30.70.3350 244 374 1.2E-37 T 31-10-2018 TK1545 b114875b9b180f520b374a3fbcf979cd 380 Gene3D G3DSA:3.30.1490.70 70 241 2.1E-69 T 31-10-2018 TK1545 b114875b9b180f520b374a3fbcf979cd 380 Gene3D G3DSA:2.20.25.320 7 67 4.8E-21 T 31-10-2018 TK1545 b114875b9b180f520b374a3fbcf979cd 380 TIGRFAM TIGR01209 TIGR01209: RNA ligase, Pab1020 family 11 380 9.2E-146 T 31-10-2018 IPR001072 RNA ligase, Pab1020 family TK1545 b114875b9b180f520b374a3fbcf979cd 380 Pfam PF09414 RNA ligase 86 240 5.7E-18 T 31-10-2018 IPR021122 RNA ligase domain, REL/Rln2 TK1776 60a6f20f7c45837cb0a770345971b91d 133 Pfam PF03686 Uncharacterised protein family (UPF0146) 4 132 9.7E-33 T 31-10-2018 IPR005353 Uncharacterised protein family UPF0146 TK1776 60a6f20f7c45837cb0a770345971b91d 133 PIRSF PIRSF016725 1 133 7.3E-30 T 31-10-2018 IPR005353 Uncharacterised protein family UPF0146 TK1776 60a6f20f7c45837cb0a770345971b91d 133 ProDom PD021130 UPF0146 MJ0688 SIMILAR ARCHAEA UNCHARACTERIZED AF0739.1 MTH1000 PYRAB01940 PH0209 VNG2609C 19 112 4.0E-47 T 31-10-2018 IPR005353 Uncharacterised protein family UPF0146 TK1776 60a6f20f7c45837cb0a770345971b91d 133 Hamap MF_00341 UPF0146 protein . 3 132 26.186 T 31-10-2018 IPR005353 Uncharacterised protein family UPF0146 TK1776 60a6f20f7c45837cb0a770345971b91d 133 SUPERFAMILY SSF51735 15 128 2.13E-5 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily TK1776 60a6f20f7c45837cb0a770345971b91d 133 Gene3D G3DSA:3.40.50.150 1 133 2.1E-25 T 31-10-2018 TK0672 04c8e81880c47f2b34effc8dd86107b4 348 PRINTS PR00419 Adrenodoxin reductase family signature 39 52 2.8E-15 T 31-10-2018 TK0672 04c8e81880c47f2b34effc8dd86107b4 348 PRINTS PR00419 Adrenodoxin reductase family signature 169 183 2.8E-15 T 31-10-2018 TK0672 04c8e81880c47f2b34effc8dd86107b4 348 PRINTS PR00419 Adrenodoxin reductase family signature 16 38 2.8E-15 T 31-10-2018 TK0672 04c8e81880c47f2b34effc8dd86107b4 348 SUPERFAMILY SSF51971 14 270 2.41E-56 T 31-10-2018 TK0672 04c8e81880c47f2b34effc8dd86107b4 348 Gene3D G3DSA:3.50.50.60 14 147 2.8E-23 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TK0672 04c8e81880c47f2b34effc8dd86107b4 348 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 16 311 5.6E-28 T 31-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TK0672 04c8e81880c47f2b34effc8dd86107b4 348 Gene3D G3DSA:3.50.50.60 148 259 1.1E-16 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TK2127 51339992fe02209a0daafee60f0e5943 440 Gene3D G3DSA:3.40.50.261 289 440 1.9E-53 T 31-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TK2127 51339992fe02209a0daafee60f0e5943 440 Gene3D G3DSA:3.40.50.720 1 127 6.7E-32 T 31-10-2018 TK2127 51339992fe02209a0daafee60f0e5943 440 SUPERFAMILY SSF51735 2 133 5.19E-23 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily TK2127 51339992fe02209a0daafee60f0e5943 440 Pfam PF13380 CoA binding domain 10 131 4.8E-17 T 31-10-2018 IPR003781 CoA-binding GO:0048037 TK2127 51339992fe02209a0daafee60f0e5943 440 SUPERFAMILY SSF52210 292 438 1.14E-39 T 31-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TK2127 51339992fe02209a0daafee60f0e5943 440 Gene3D G3DSA:3.40.50.261 136 288 5.2E-60 T 31-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TK2127 51339992fe02209a0daafee60f0e5943 440 SMART SM00881 6 100 1.2E-20 T 31-10-2018 IPR003781 CoA-binding GO:0048037 TK2127 51339992fe02209a0daafee60f0e5943 440 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 148 285 3.0E-57 T 31-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain TK2127 51339992fe02209a0daafee60f0e5943 440 SUPERFAMILY SSF52210 130 285 4.58E-44 T 31-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TK1614 9d384a2c5975d34ccee0e61ca1540457 154 TIGRFAM TIGR01958 nuoE_fam: NADH-quinone oxidoreductase, E subunit 8 148 5.5E-45 T 31-10-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TK1614 9d384a2c5975d34ccee0e61ca1540457 154 PIRSF PIRSF000216 6 154 5.0E-61 T 31-10-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TK1614 9d384a2c5975d34ccee0e61ca1540457 154 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 7 148 4.2E-55 T 31-10-2018 TK1614 9d384a2c5975d34ccee0e61ca1540457 154 SUPERFAMILY SSF52833 7 151 1.12E-54 T 31-10-2018 IPR036249 Thioredoxin-like superfamily TK1614 9d384a2c5975d34ccee0e61ca1540457 154 ProSitePatterns PS01099 Respiratory-chain NADH dehydrogenase 24 Kd subunit signature. 105 123 - T 31-10-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TK1614 9d384a2c5975d34ccee0e61ca1540457 154 Gene3D G3DSA:1.10.10.1590 5 65 3.3E-20 T 31-10-2018 TK1614 9d384a2c5975d34ccee0e61ca1540457 154 Gene3D G3DSA:3.40.30.10 66 153 6.4E-33 T 31-10-2018 TK1112 f617995754589738adcfe6e07b99d35c 60 Pfam PF07650 KH domain 3 55 2.0E-5 T 31-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1112 f617995754589738adcfe6e07b99d35c 60 Gene3D G3DSA:3.30.300.20 4 60 9.8E-8 T 31-10-2018 IPR015946 K homology domain-like, alpha/beta TK1112 f617995754589738adcfe6e07b99d35c 60 SUPERFAMILY SSF54814 11 58 2.75E-8 T 31-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 TK0031 c3c64bf77e10d2fc2890c20276ffda71 132 Hamap MF_00757 Ribonuclease P protein component 4 [rnp4]. 10 109 26.435 T 31-10-2018 IPR016432 Ribonuclease P, protein component 4 GO:0001682|GO:0004526 TK0031 c3c64bf77e10d2fc2890c20276ffda71 132 Gene3D G3DSA:1.20.5.420 6 63 1.9E-22 T 31-10-2018 TK0031 c3c64bf77e10d2fc2890c20276ffda71 132 PIRSF PIRSF004878 1 116 1.1E-44 T 31-10-2018 IPR016432 Ribonuclease P, protein component 4 GO:0001682|GO:0004526 TK0031 c3c64bf77e10d2fc2890c20276ffda71 132 Gene3D G3DSA:2.20.25.200 64 119 2.3E-26 T 31-10-2018 TK0031 c3c64bf77e10d2fc2890c20276ffda71 132 Pfam PF04032 RNAse P Rpr2/Rpp21/SNM1 subunit domain 21 100 3.2E-17 T 31-10-2018 IPR007175 RNAse P, Rpr2/Rpp21 subunit Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 TK0850 ca7b624b090e30e0e67975d4bbef17d8 431 Pfam PF07282 Putative transposase DNA-binding domain 314 383 1.0E-20 T 31-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal TK0850 ca7b624b090e30e0e67975d4bbef17d8 431 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 264 341 1.4E-8 T 31-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal TK0850 ca7b624b090e30e0e67975d4bbef17d8 431 Pfam PF01385 Probable transposase 169 294 1.5E-37 T 31-10-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 TK1431 01699b16a148b490cfeb30f3b3085aa8 421 Gene3D G3DSA:3.40.50.720 182 420 3.8E-93 T 31-10-2018 TK1431 01699b16a148b490cfeb30f3b3085aa8 421 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 91 105 4.4E-29 T 31-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 TK1431 01699b16a148b490cfeb30f3b3085aa8 421 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 216 236 4.4E-29 T 31-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 TK1431 01699b16a148b490cfeb30f3b3085aa8 421 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 173 195 4.4E-29 T 31-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 TK1431 01699b16a148b490cfeb30f3b3085aa8 421 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 345 356 4.4E-29 T 31-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 TK1431 01699b16a148b490cfeb30f3b3085aa8 421 Gene3D G3DSA:3.40.50.10860 36 180 2.6E-67 T 31-10-2018 TK1431 01699b16a148b490cfeb30f3b3085aa8 421 SMART SM00839 184 417 3.7E-94 T 31-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 TK1431 01699b16a148b490cfeb30f3b3085aa8 421 SUPERFAMILY SSF53223 4 184 3.17E-68 T 31-10-2018 TK1431 01699b16a148b490cfeb30f3b3085aa8 421 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 182 417 1.2E-73 T 31-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 TK1431 01699b16a148b490cfeb30f3b3085aa8 421 PIRSF PIRSF000185 1 420 2.0E-168 T 31-10-2018 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 TK1431 01699b16a148b490cfeb30f3b3085aa8 421 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 34 161 5.1E-54 T 31-10-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 TK1431 01699b16a148b490cfeb30f3b3085aa8 421 SUPERFAMILY SSF51735 182 419 1.34E-77 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily TK1431 01699b16a148b490cfeb30f3b3085aa8 421 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 99 112 - T 31-10-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 TK0198 063e5c667ce43893f920a89483edff21 173 SUPERFAMILY SSF103473 3 168 2.09E-15 T 31-10-2018 IPR036259 MFS transporter superfamily TK0198 063e5c667ce43893f920a89483edff21 173 Pfam PF07690 Major Facilitator Superfamily 5 165 1.8E-10 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TK0198 063e5c667ce43893f920a89483edff21 173 Gene3D G3DSA:1.20.1250.20 1 165 1.1E-11 T 31-10-2018 TK1342 3e49567540a75abaade36a5b88dd12ab 318 Gene3D G3DSA:1.10.443.10 108 312 6.4E-31 T 31-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 TK1342 3e49567540a75abaade36a5b88dd12ab 318 Pfam PF16795 Archaeal phage integrase 112 307 9.1E-14 T 31-10-2018 IPR031857 Integrase SSV1, C-terminal TK1342 3e49567540a75abaade36a5b88dd12ab 318 SUPERFAMILY SSF56349 21 156 2.63E-6 T 31-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 TK1897 72c51c4c5b5612087469ee1edd35410a 127 ProDom PD020987 PF0014 UNCHARACTERIZED AF1250 PH0127 MJ0105 MA4414 ARCHAEAL 1 104 6.0E-52 T 31-10-2018 IPR007417 Protein of unknown function DUF473 TK1897 72c51c4c5b5612087469ee1edd35410a 127 Pfam PF04322 Protein of unknown function (DUF473) 1 116 4.0E-32 T 31-10-2018 IPR007417 Protein of unknown function DUF473 TK1016 cee4d7b0244af25340b938b2af67db3e 141 Pfam PF05763 Protein of unknown function (DUF835) 26 138 1.6E-21 T 31-10-2018 IPR008553 Domain of unknown function DUF835 TK1140 38c8ee08db39e984df6937fd6c47cb09 455 SUPERFAMILY SSF55681 156 445 3.19E-89 T 31-10-2018 TK1140 38c8ee08db39e984df6937fd6c47cb09 455 PIRSF PIRSF001529 1 447 1.8E-154 T 31-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 TK1140 38c8ee08db39e984df6937fd6c47cb09 455 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 443 42.073 T 31-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 TK1140 38c8ee08db39e984df6937fd6c47cb09 455 SUPERFAMILY SSF46589 1 115 4.66E-28 T 31-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 TK1140 38c8ee08db39e984df6937fd6c47cb09 455 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 109 1.6E-27 T 31-10-2018 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: R-HSA-2408557|Reactome: R-HSA-379716 TK1140 38c8ee08db39e984df6937fd6c47cb09 455 TIGRFAM TIGR00414 serS: serine--tRNA ligase 1 438 5.7E-163 T 31-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 TK1140 38c8ee08db39e984df6937fd6c47cb09 455 PRINTS PR00981 Seryl-tRNA synthetase signature 372 388 2.5E-33 T 31-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 TK1140 38c8ee08db39e984df6937fd6c47cb09 455 PRINTS PR00981 Seryl-tRNA synthetase signature 285 297 2.5E-33 T 31-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 TK1140 38c8ee08db39e984df6937fd6c47cb09 455 PRINTS PR00981 Seryl-tRNA synthetase signature 354 370 2.5E-33 T 31-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 TK1140 38c8ee08db39e984df6937fd6c47cb09 455 PRINTS PR00981 Seryl-tRNA synthetase signature 297 310 2.5E-33 T 31-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 TK1140 38c8ee08db39e984df6937fd6c47cb09 455 PRINTS PR00981 Seryl-tRNA synthetase signature 337 350 2.5E-33 T 31-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 TK1140 38c8ee08db39e984df6937fd6c47cb09 455 Gene3D G3DSA:1.10.287.40 1 107 2.7E-34 T 31-10-2018 TK1140 38c8ee08db39e984df6937fd6c47cb09 455 Gene3D G3DSA:3.30.930.10 108 455 1.5E-136 T 31-10-2018 TK1140 38c8ee08db39e984df6937fd6c47cb09 455 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 243 421 6.7E-38 T 31-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 TK0155 e4af80a62da12f79ed9939f7486a746e 741 Gene3D G3DSA:2.40.50.140 128 202 4.2E-14 T 31-10-2018 TK0155 e4af80a62da12f79ed9939f7486a746e 741 SMART SM00316 131 196 1.1E-14 T 31-10-2018 IPR022967 RNA-binding domain, S1 TK0155 e4af80a62da12f79ed9939f7486a746e 741 Pfam PF01336 OB-fold nucleic acid binding domain 227 296 8.9E-11 T 31-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 TK0155 e4af80a62da12f79ed9939f7486a746e 741 SUPERFAMILY SSF50249 121 194 1.04E-12 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold TK0155 e4af80a62da12f79ed9939f7486a746e 741 SUPERFAMILY SSF57938 5 32 7.19E-5 T 31-10-2018 IPR036410 Heat shock protein DnaJ, cysteine-rich domain superfamily TK0155 e4af80a62da12f79ed9939f7486a746e 741 SUPERFAMILY SSF64182 336 734 1.1E-42 T 31-10-2018 IPR038763 DHH phosphoesterase superfamily TK0155 e4af80a62da12f79ed9939f7486a746e 741 SUPERFAMILY SSF50249 225 296 2.1E-11 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold TK0155 e4af80a62da12f79ed9939f7486a746e 741 Gene3D G3DSA:2.10.230.10 1 88 2.5E-6 T 31-10-2018 TK0155 e4af80a62da12f79ed9939f7486a746e 741 Gene3D G3DSA:2.40.50.140 218 305 4.3E-8 T 31-10-2018 TK0155 e4af80a62da12f79ed9939f7486a746e 741 Gene3D G3DSA:3.90.1640.30 333 541 3.6E-9 T 31-10-2018 TK0155 e4af80a62da12f79ed9939f7486a746e 741 Pfam PF00575 S1 RNA binding domain 130 193 2.0E-9 T 31-10-2018 IPR003029 S1 domain GO:0003676 TK1535 94a401453e31cdb4f92799e0a8affbc7 66 Pfam PF00831 Ribosomal L29 protein 4 61 8.1E-18 T 31-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1535 94a401453e31cdb4f92799e0a8affbc7 66 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 1 61 15.682 T 31-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1535 94a401453e31cdb4f92799e0a8affbc7 66 ProSitePatterns PS00579 Ribosomal protein L29 signature. 40 54 - T 31-10-2018 IPR018254 Ribosomal protein L29, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1535 94a401453e31cdb4f92799e0a8affbc7 66 TIGRFAM TIGR00012 L29: ribosomal protein uL29 5 61 9.0E-21 T 31-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1535 94a401453e31cdb4f92799e0a8affbc7 66 SUPERFAMILY SSF46561 1 61 2.62E-16 T 31-10-2018 IPR036049 Ribosomal protein L29/L35 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1535 94a401453e31cdb4f92799e0a8affbc7 66 Gene3D G3DSA:1.10.287.310 1 66 1.7E-19 T 31-10-2018 TK2074 31a1f50b5e30b04381325cdd180d70ad 351 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 173 191 6.8E-21 T 31-10-2018 TK2074 31a1f50b5e30b04381325cdd180d70ad 351 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 302 324 6.8E-21 T 31-10-2018 TK2074 31a1f50b5e30b04381325cdd180d70ad 351 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 118 136 6.8E-21 T 31-10-2018 TK2074 31a1f50b5e30b04381325cdd180d70ad 351 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 21 40 6.8E-21 T 31-10-2018 TK2074 31a1f50b5e30b04381325cdd180d70ad 351 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 275 291 6.8E-21 T 31-10-2018 TK2074 31a1f50b5e30b04381325cdd180d70ad 351 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 20 42 1.4E-13 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TK2074 31a1f50b5e30b04381325cdd180d70ad 351 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 169 193 1.4E-13 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TK2074 31a1f50b5e30b04381325cdd180d70ad 351 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 312 330 1.4E-13 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TK2074 31a1f50b5e30b04381325cdd180d70ad 351 SUPERFAMILY SSF51971 17 284 1.88E-54 T 31-10-2018 TK2074 31a1f50b5e30b04381325cdd180d70ad 351 Gene3D G3DSA:3.50.50.60 141 283 9.9E-35 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TK2074 31a1f50b5e30b04381325cdd180d70ad 351 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 19 337 6.6E-37 T 31-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TK2074 31a1f50b5e30b04381325cdd180d70ad 351 Gene3D G3DSA:3.50.50.60 15 140 1.9E-21 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TK0795 bc7f01e2ff538f21cb890c343cd2b140 700 SUPERFAMILY SSF52540 385 590 1.24E-14 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK0795 bc7f01e2ff538f21cb890c343cd2b140 700 SMART SM00382 394 589 4.0E-9 T 31-10-2018 IPR003593 AAA+ ATPase domain TK0795 bc7f01e2ff538f21cb890c343cd2b140 700 Pfam PF07728 AAA domain (dynein-related subfamily) 397 579 2.4E-16 T 31-10-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 TK1251 0bf1c75c8770745b273fa17991d6c7d2 151 Pfam PF00312 Ribosomal protein S15 73 148 4.3E-21 T 31-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TK1251 0bf1c75c8770745b273fa17991d6c7d2 151 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 90 133 2.0E-5 T 31-10-2018 TK1251 0bf1c75c8770745b273fa17991d6c7d2 151 Gene3D G3DSA:1.10.287.10 83 151 1.1E-32 T 31-10-2018 TK1251 0bf1c75c8770745b273fa17991d6c7d2 151 ProSitePatterns PS00362 Ribosomal protein S15 signature. 98 128 - T 31-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TK1251 0bf1c75c8770745b273fa17991d6c7d2 151 SMART SM01386 1 60 1.4E-35 T 31-10-2018 IPR012606 Ribosomal protein S13/S15, N-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1251 0bf1c75c8770745b273fa17991d6c7d2 151 Gene3D G3DSA:1.10.8.1030 36 82 2.7E-21 T 31-10-2018 TK1251 0bf1c75c8770745b273fa17991d6c7d2 151 SMART SM01387 70 149 1.5E-28 T 31-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TK1251 0bf1c75c8770745b273fa17991d6c7d2 151 Hamap MF_01343_A 30S ribosomal protein S15 [rpsO]. 3 149 38.02 T 31-10-2018 IPR023029 Ribosomal protein S15P Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1251 0bf1c75c8770745b273fa17991d6c7d2 151 Pfam PF08069 Ribosomal S13/S15 N-terminal domain 1 60 1.2E-27 T 31-10-2018 IPR012606 Ribosomal protein S13/S15, N-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1251 0bf1c75c8770745b273fa17991d6c7d2 151 SUPERFAMILY SSF47060 66 142 8.83E-26 T 31-10-2018 IPR009068 S15/NS1, RNA-binding TK0510 0c0741dab0000f9005f3218e7bee00fc 266 SUPERFAMILY SSF143597 107 259 6.41E-30 T 31-10-2018 IPR036888 DNA integrity scanning protein, DisA, N-terminal domain superfamily TK0510 0c0741dab0000f9005f3218e7bee00fc 266 PIRSF PIRSF019073 1 266 9.5E-77 T 31-10-2018 IPR014499 Diadenylate cyclase, DacZ-type TK0510 0c0741dab0000f9005f3218e7bee00fc 266 Hamap MF_00840 Diadenylate cyclase [dacZ]. 7 265 35.303 T 31-10-2018 IPR014499 Diadenylate cyclase, DacZ-type TK0510 0c0741dab0000f9005f3218e7bee00fc 266 Pfam PF02457 DisA bacterial checkpoint controller nucleotide-binding 132 254 2.4E-22 T 31-10-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal TK0510 0c0741dab0000f9005f3218e7bee00fc 266 Gene3D G3DSA:3.40.1700.10 170 265 1.7E-14 T 31-10-2018 IPR036888 DNA integrity scanning protein, DisA, N-terminal domain superfamily TK1675 584422471a6718e94f3952da74869ef0 422 Pfam PF00082 Subtilase family 133 409 1.1E-47 T 31-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 TK1675 584422471a6718e94f3952da74869ef0 422 SUPERFAMILY SSF52743 107 420 6.15E-85 T 31-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 TK1675 584422471a6718e94f3952da74869ef0 422 Gene3D G3DSA:3.40.50.200 103 422 2.2E-114 T 31-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 TK1675 584422471a6718e94f3952da74869ef0 422 SUPERFAMILY SSF54897 43 90 4.25E-7 T 31-10-2018 TK1675 584422471a6718e94f3952da74869ef0 422 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 135 146 - T 31-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site TK1675 584422471a6718e94f3952da74869ef0 422 Gene3D G3DSA:3.30.70.80 25 93 2.8E-38 T 31-10-2018 IPR037045 Peptidase S8 propeptide/proteinase inhibitor I9 superfamily Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 TK1675 584422471a6718e94f3952da74869ef0 422 PRINTS PR00723 Subtilisin serine protease family (S8) signature 173 186 5.0E-19 T 31-10-2018 IPR015500 Peptidase S8, subtilisin-related TK1675 584422471a6718e94f3952da74869ef0 422 PRINTS PR00723 Subtilisin serine protease family (S8) signature 345 361 5.0E-19 T 31-10-2018 IPR015500 Peptidase S8, subtilisin-related TK1675 584422471a6718e94f3952da74869ef0 422 PRINTS PR00723 Subtilisin serine protease family (S8) signature 130 149 5.0E-19 T 31-10-2018 IPR015500 Peptidase S8, subtilisin-related TK1675 584422471a6718e94f3952da74869ef0 422 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 346 356 - T 31-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site TK1637 63f1c079096023ce112a31e1454c9503 260 ProSitePatterns PS00388 Proteasome alpha-type subunits signature. 10 32 - T 31-10-2018 IPR000426 Proteasome alpha-subunit, N-terminal domain GO:0004175|GO:0006511|GO:0019773 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 TK1637 63f1c079096023ce112a31e1454c9503 260 Hamap MF_00289_A Proteasome subunit alpha [prcA]. 5 234 47.733 T 31-10-2018 IPR019982 Proteasome alpha subunit, archaeal GO:0004298|GO:0005839|GO:0051603 TK1637 63f1c079096023ce112a31e1454c9503 260 SUPERFAMILY SSF56235 7 241 1.02E-82 T 31-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TK1637 63f1c079096023ce112a31e1454c9503 260 Gene3D G3DSA:3.60.20.10 5 253 1.4E-91 T 31-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TK1637 63f1c079096023ce112a31e1454c9503 260 TIGRFAM TIGR03633 arc_protsome_A: proteasome endopeptidase complex, archaeal, alpha subunit 8 234 6.8E-106 T 31-10-2018 IPR019982 Proteasome alpha subunit, archaeal GO:0004298|GO:0005839|GO:0051603 TK1637 63f1c079096023ce112a31e1454c9503 260 Pfam PF10584 Proteasome subunit A N-terminal signature 10 32 4.0E-12 T 31-10-2018 IPR000426 Proteasome alpha-subunit, N-terminal domain GO:0004175|GO:0006511|GO:0019773 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 TK1637 63f1c079096023ce112a31e1454c9503 260 Pfam PF00227 Proteasome subunit 33 215 8.4E-65 T 31-10-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 TK1637 63f1c079096023ce112a31e1454c9503 260 SMART SM00948 10 32 3.4E-10 T 31-10-2018 IPR000426 Proteasome alpha-subunit, N-terminal domain GO:0004175|GO:0006511|GO:0019773 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 TK1965 fe7b07bf609acdd22cd0647fe971fbe5 286 TIGRFAM TIGR00722 ttdA_fumA_fumB: hydrolyase, tartrate alpha subunit/fumarate domain protein, Fe-S type 6 275 1.6E-116 T 31-10-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 TK1965 fe7b07bf609acdd22cd0647fe971fbe5 286 Pfam PF05681 Fumarate hydratase (Fumerase) 8 272 5.4E-94 T 31-10-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 TK0900 16d1919b8f7addac72aa3f6aafd6b498 206 Gene3D G3DSA:1.10.150.280 93 190 4.6E-43 T 31-10-2018 TK0900 16d1919b8f7addac72aa3f6aafd6b498 206 Gene3D G3DSA:2.40.50.140 23 92 3.7E-22 T 31-10-2018 TK0900 16d1919b8f7addac72aa3f6aafd6b498 206 Pfam PF04919 Protein of unknown function (DUF655) 23 198 2.0E-69 T 31-10-2018 IPR007003 Protein of unknown function DUF655 TK0900 16d1919b8f7addac72aa3f6aafd6b498 206 SUPERFAMILY SSF160975 23 199 2.35E-92 T 31-10-2018 TK1818 10db6d807c3d0155e17264609ef7c2a9 198 Pfam PF12389 Camelysin metallo-endopeptidase 4 96 6.9E-7 T 31-10-2018 IPR022121 Peptidase M73, camelysin TK1771 993a29907bb184be83a06ab045bc04c4 448 Pfam PF13416 Bacterial extracellular solute-binding protein 91 386 1.8E-53 T 31-10-2018 IPR006059 Bacterial extracellular solute-binding protein TK1771 993a29907bb184be83a06ab045bc04c4 448 ProSitePatterns PS01037 Bacterial extracellular solute-binding proteins, family 1 signature. 178 195 - T 31-10-2018 IPR006061 Solute-binding family 1, conserved site GO:0055085 TK1771 993a29907bb184be83a06ab045bc04c4 448 PRINTS PR00181 Maltose binding protein signature 402 421 3.3E-13 T 31-10-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0008643|GO:0015144 TK1771 993a29907bb184be83a06ab045bc04c4 448 PRINTS PR00181 Maltose binding protein signature 175 194 3.3E-13 T 31-10-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0008643|GO:0015144 TK1771 993a29907bb184be83a06ab045bc04c4 448 PRINTS PR00181 Maltose binding protein signature 196 215 3.3E-13 T 31-10-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0008643|GO:0015144 TK1771 993a29907bb184be83a06ab045bc04c4 448 PRINTS PR00181 Maltose binding protein signature 113 131 3.3E-13 T 31-10-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0008643|GO:0015144 TK1771 993a29907bb184be83a06ab045bc04c4 448 PRINTS PR00181 Maltose binding protein signature 273 292 3.3E-13 T 31-10-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0008643|GO:0015144 TK1771 993a29907bb184be83a06ab045bc04c4 448 PRINTS PR00181 Maltose binding protein signature 343 364 3.3E-13 T 31-10-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0008643|GO:0015144 TK1771 993a29907bb184be83a06ab045bc04c4 448 SUPERFAMILY SSF53850 70 441 7.09E-95 T 31-10-2018 TK1771 993a29907bb184be83a06ab045bc04c4 448 Gene3D G3DSA:3.40.190.10 76 402 4.1E-143 T 31-10-2018 TK1771 993a29907bb184be83a06ab045bc04c4 448 Gene3D G3DSA:3.40.190.10 183 417 4.1E-143 T 31-10-2018 TK0493 076c6b954ac73b21f81f01c8ccf5952c 697 Pfam PF05753 Translocon-associated protein beta (TRAPB) 339 443 2.7E-7 T 31-10-2018 TK0559 667ada1a8207d2ce055bebc3ecd33f78 182 SUPERFAMILY SSF46785 7 143 1.1E-21 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TK0559 667ada1a8207d2ce055bebc3ecd33f78 182 SMART SM00418 15 99 6.4E-4 T 31-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TK0559 667ada1a8207d2ce055bebc3ecd33f78 182 Pfam PF12840 Helix-turn-helix domain 15 70 1.4E-11 T 31-10-2018 TK0559 667ada1a8207d2ce055bebc3ecd33f78 182 Gene3D G3DSA:1.10.10.10 8 92 2.0E-17 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TK0935 7f8ca1d1051731859260b851c6293701 337 TIGRFAM TIGR02122 TRAP_TAXI: TRAP transporter solute receptor, TAXI family 14 328 2.5E-100 T 31-10-2018 IPR011852 TRAP transporter solute receptor, TAXI family TK0935 7f8ca1d1051731859260b851c6293701 337 SUPERFAMILY SSF53850 40 329 8.71E-78 T 31-10-2018 TK0935 7f8ca1d1051731859260b851c6293701 337 Gene3D G3DSA:3.40.190.10 44 328 9.9E-102 T 31-10-2018 TK0935 7f8ca1d1051731859260b851c6293701 337 Pfam PF16868 NMT1-like family 44 328 2.1E-87 T 31-10-2018 IPR011852 TRAP transporter solute receptor, TAXI family TK0935 7f8ca1d1051731859260b851c6293701 337 Gene3D G3DSA:3.40.190.10 126 263 9.9E-102 T 31-10-2018 TK0773 5d5a18db241411113b4c727b352051de 648 SUPERFAMILY SSF52540 4 372 1.32E-20 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK0773 5d5a18db241411113b4c727b352051de 648 Pfam PF13175 AAA ATPase domain 9 352 9.4E-40 T 31-10-2018 TK0773 5d5a18db241411113b4c727b352051de 648 Gene3D G3DSA:3.40.50.300 4 375 6.5E-30 T 31-10-2018 TK1513 a0289479648ef06422c83d44d6fb7858 83 SUPERFAMILY SSF50104 2 79 7.82E-20 T 31-10-2018 IPR008991 Translation protein SH3-like domain superfamily TK1513 a0289479648ef06422c83d44d6fb7858 83 Hamap MF_00721 50S ribosomal protein L14e [rpl14e]. 1 79 27.406 T 31-10-2018 IPR023651 Ribosomal protein L14e GO:0003735|GO:0005840|GO:0006412 TK1513 a0289479648ef06422c83d44d6fb7858 83 Gene3D G3DSA:2.30.30.30 2 82 1.1E-28 T 31-10-2018 IPR014722 Ribosomal protein L2, domain 2 TK0563 5bb256915792337e5b3a4b9c26f3cd42 154 Gene3D G3DSA:3.30.479.10 10 152 5.3E-32 T 31-10-2018 IPR038418 6-pyruvoyl tetrahydropterin synthase/QueD superfamily Reactome: R-HSA-1474151 TK0563 5bb256915792337e5b3a4b9c26f3cd42 154 SUPERFAMILY SSF55620 12 152 4.56E-35 T 31-10-2018 TK0563 5bb256915792337e5b3a4b9c26f3cd42 154 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 11 151 2.5E-28 T 31-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 TK1835 3bb552f554d5a61599e1f923a28e7644 206 SUPERFAMILY SSF53182 1 199 1.29E-70 T 31-10-2018 IPR036440 Peptidase C15, pyroglutamyl peptidase I-like superfamily MetaCyc: PWY-7942 TK1835 3bb552f554d5a61599e1f923a28e7644 206 ProSitePatterns PS01334 Pyrrolidone-carboxylate peptidase cysteine active site. 128 142 - T 31-10-2018 IPR033694 Pyroglutamyl peptidase I, Cys active site MetaCyc: PWY-7942 TK1835 3bb552f554d5a61599e1f923a28e7644 206 PIRSF PIRSF015592 1 205 3.6E-78 T 31-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 TK1835 3bb552f554d5a61599e1f923a28e7644 206 ProSitePatterns PS01333 Pyrrolidone-carboxylate peptidase glutamic acid active site. 67 83 - T 31-10-2018 IPR033693 Pyroglutamyl peptidase I, Glu active site MetaCyc: PWY-7942 TK1835 3bb552f554d5a61599e1f923a28e7644 206 Pfam PF01470 Pyroglutamyl peptidase 1 198 5.7E-76 T 31-10-2018 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like MetaCyc: PWY-7942 TK1835 3bb552f554d5a61599e1f923a28e7644 206 Hamap MF_00417 Pyrrolidone-carboxylate peptidase [pcp]. 1 198 37.608 T 31-10-2018 IPR029762 Pyroglutamyl peptidase I, bacterial-type GO:0005829|GO:0006508|GO:0008234|GO:0016920 MetaCyc: PWY-7942 TK1835 3bb552f554d5a61599e1f923a28e7644 206 TIGRFAM TIGR00504 pyro_pdase: pyroglutamyl-peptidase I 2 197 4.8E-74 T 31-10-2018 IPR029762 Pyroglutamyl peptidase I, bacterial-type GO:0005829|GO:0006508|GO:0008234|GO:0016920 MetaCyc: PWY-7942 TK1835 3bb552f554d5a61599e1f923a28e7644 206 Gene3D G3DSA:3.40.630.20 1 204 4.6E-77 T 31-10-2018 IPR036440 Peptidase C15, pyroglutamyl peptidase I-like superfamily MetaCyc: PWY-7942 TK1835 3bb552f554d5a61599e1f923a28e7644 206 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 78 98 1.5E-42 T 31-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 TK1835 3bb552f554d5a61599e1f923a28e7644 206 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 130 146 1.5E-42 T 31-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 TK1835 3bb552f554d5a61599e1f923a28e7644 206 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 60 72 1.5E-42 T 31-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 TK1835 3bb552f554d5a61599e1f923a28e7644 206 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 3 26 1.5E-42 T 31-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 TK1835 3bb552f554d5a61599e1f923a28e7644 206 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 160 172 1.5E-42 T 31-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 TK2130 ee318f231efa9bc99eeeb442f9d85118 175 Pfam PF02572 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP 8 175 4.2E-63 T 31-10-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17 TK2130 ee318f231efa9bc99eeeb442f9d85118 175 PIRSF PIRSF015617 1 175 7.5E-63 T 31-10-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17 TK2130 ee318f231efa9bc99eeeb442f9d85118 175 TIGRFAM TIGR00708 cobA: cob(I)yrinic acid a,c-diamide adenosyltransferase 3 175 6.3E-73 T 31-10-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17 TK2130 ee318f231efa9bc99eeeb442f9d85118 175 Gene3D G3DSA:3.40.50.300 1 175 6.7E-67 T 31-10-2018 TK2130 ee318f231efa9bc99eeeb442f9d85118 175 SUPERFAMILY SSF52540 4 175 1.11E-58 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK1481 2e10765293351cde3a9a8467f2288c14 447 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 327 424 1.6E-17 T 31-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 TK1481 2e10765293351cde3a9a8467f2288c14 447 SUPERFAMILY SSF55424 318 441 3.26E-25 T 31-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 TK1481 2e10765293351cde3a9a8467f2288c14 447 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 144 162 7.9E-28 T 31-10-2018 TK1481 2e10765293351cde3a9a8467f2288c14 447 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 7.9E-28 T 31-10-2018 TK1481 2e10765293351cde3a9a8467f2288c14 447 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 98 116 7.9E-28 T 31-10-2018 TK1481 2e10765293351cde3a9a8467f2288c14 447 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 227 243 7.9E-28 T 31-10-2018 TK1481 2e10765293351cde3a9a8467f2288c14 447 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 253 275 7.9E-28 T 31-10-2018 TK1481 2e10765293351cde3a9a8467f2288c14 447 Gene3D G3DSA:3.50.50.60 5 333 2.0E-120 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TK1481 2e10765293351cde3a9a8467f2288c14 447 Gene3D G3DSA:3.50.50.60 107 423 2.0E-120 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TK1481 2e10765293351cde3a9a8467f2288c14 447 SUPERFAMILY SSF51905 1 306 2.84E-48 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TK1481 2e10765293351cde3a9a8467f2288c14 447 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 6.2E-22 T 31-10-2018 TK1481 2e10765293351cde3a9a8467f2288c14 447 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 144 169 6.2E-22 T 31-10-2018 TK1481 2e10765293351cde3a9a8467f2288c14 447 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 268 275 6.2E-22 T 31-10-2018 TK1481 2e10765293351cde3a9a8467f2288c14 447 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 228 242 6.2E-22 T 31-10-2018 TK1481 2e10765293351cde3a9a8467f2288c14 447 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 295 1.2E-56 T 31-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TK0878 2de5509661d80da2d1425663468369f0 136 ProSitePatterns PS00302 Eukaryotic initiation factor 5A hypusine signature. 35 42 - T 31-10-2018 IPR019769 Translation elongation factor, IF5A, hypusine site GO:0003723|GO:0003746|GO:0043022|GO:0045901|GO:0045905 TK0878 2de5509661d80da2d1425663468369f0 136 PIRSF PIRSF003025 1 136 2.1E-44 T 31-10-2018 IPR001884 Translation elongation factor IF5A-like GO:0003723|GO:0003746|GO:0043022|GO:0045901 TK0878 2de5509661d80da2d1425663468369f0 136 SUPERFAMILY SSF50249 71 130 8.14E-13 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold TK0878 2de5509661d80da2d1425663468369f0 136 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 9 40 5.9E-5 T 31-10-2018 IPR013185 Translation elongation factor, KOW-like TK0878 2de5509661d80da2d1425663468369f0 136 Gene3D G3DSA:2.40.50.140 71 135 9.4E-30 T 31-10-2018 TK0878 2de5509661d80da2d1425663468369f0 136 SUPERFAMILY SSF50104 5 78 1.05E-20 T 31-10-2018 IPR008991 Translation protein SH3-like domain superfamily TK0878 2de5509661d80da2d1425663468369f0 136 TIGRFAM TIGR00037 eIF_5A: translation elongation factor IF5A 4 133 2.8E-47 T 31-10-2018 IPR001884 Translation elongation factor IF5A-like GO:0003723|GO:0003746|GO:0043022|GO:0045901 TK0878 2de5509661d80da2d1425663468369f0 136 Hamap MF_00085 Translation initiation factor 5A [eif5a]. 3 133 34.328 T 31-10-2018 IPR022847 Translation elongation factor IF5A, archaeal TK0878 2de5509661d80da2d1425663468369f0 136 Pfam PF01287 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold 70 134 4.0E-12 T 31-10-2018 IPR020189 Translation elongation factor, IF5A C-terminal GO:0003723|GO:0003746|GO:0006452|GO:0043022|GO:0045901|GO:0045905 TK0878 2de5509661d80da2d1425663468369f0 136 SMART SM01376 70 134 3.0E-18 T 31-10-2018 IPR020189 Translation elongation factor, IF5A C-terminal GO:0003723|GO:0003746|GO:0006452|GO:0043022|GO:0045901|GO:0045905 TK0878 2de5509661d80da2d1425663468369f0 136 Gene3D G3DSA:2.30.30.30 1 70 1.4E-28 T 31-10-2018 IPR014722 Ribosomal protein L2, domain 2 TK0560 80f626bb797dff1ad63979b994540828 91 Hamap MF_01122 DNA/RNA-binding protein Alba [albA]. 1 90 27.875 T 31-10-2018 IPR013795 DNA/RNA-binding protein Alba GO:0003677|GO:0003723|GO:0005737 TK0560 80f626bb797dff1ad63979b994540828 91 PIRSF PIRSF028732 1 91 7.4E-40 T 31-10-2018 IPR013795 DNA/RNA-binding protein Alba GO:0003677|GO:0003723|GO:0005737 TK0560 80f626bb797dff1ad63979b994540828 91 TIGRFAM TIGR00285 TIGR00285: DNA-binding protein Alba 4 90 8.3E-46 T 31-10-2018 IPR013795 DNA/RNA-binding protein Alba GO:0003677|GO:0003723|GO:0005737 TK0560 80f626bb797dff1ad63979b994540828 91 SUPERFAMILY SSF82704 5 90 3.79E-27 T 31-10-2018 IPR036882 Alba-like domain superfamily GO:0003676 TK0560 80f626bb797dff1ad63979b994540828 91 Pfam PF01918 Alba 6 66 2.5E-21 T 31-10-2018 IPR002775 DNA/RNA-binding protein Alba-like GO:0003676 TK0560 80f626bb797dff1ad63979b994540828 91 Gene3D G3DSA:3.30.110.20 2 90 3.0E-38 T 31-10-2018 IPR036882 Alba-like domain superfamily GO:0003676 TK0560 80f626bb797dff1ad63979b994540828 91 ProDom PD010497 ALBA DNA-BINDING DNA/RNA-BINDING RNA-BINDING ACETYLATION 3D-STRUCTURE DNA CONDENSATION AF1 SSO10B 8 90 5.0E-33 T 31-10-2018 TK1670 29c351c144321f9f565f261d53ae0242 745 Pfam PF00432 Prenyltransferase and squalene oxidase repeat 304 341 2.4E-4 T 31-10-2018 IPR001330 PFTB repeat GO:0003824 TK1670 29c351c144321f9f565f261d53ae0242 745 Pfam PF00432 Prenyltransferase and squalene oxidase repeat 73 110 3.2E-4 T 31-10-2018 IPR001330 PFTB repeat GO:0003824 TK1670 29c351c144321f9f565f261d53ae0242 745 ProSitePatterns PS00018 EF-hand calcium-binding domain. 727 739 - T 31-10-2018 IPR018247 EF-Hand 1, calcium-binding site TK1670 29c351c144321f9f565f261d53ae0242 745 SUPERFAMILY SSF48239 275 483 1.93E-16 T 31-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid TK1670 29c351c144321f9f565f261d53ae0242 745 PIRSF PIRSF018649 3 745 0.0 T 31-10-2018 IPR016731 Uncharacterised conserved protein UCP018649 TK1670 29c351c144321f9f565f261d53ae0242 745 Gene3D G3DSA:1.50.10.20 24 218 8.2E-16 T 31-10-2018 TK1670 29c351c144321f9f565f261d53ae0242 745 Gene3D G3DSA:1.50.10.20 265 390 6.4E-12 T 31-10-2018 TK1670 29c351c144321f9f565f261d53ae0242 745 SUPERFAMILY SSF48239 446 547 1.12E-8 T 31-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid TK1670 29c351c144321f9f565f261d53ae0242 745 SUPERFAMILY SSF48239 47 215 3.84E-21 T 31-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid TK1517 3d980e5923e2e150f02cbb053fbbb8ef 196 Gene3D G3DSA:3.40.50.300 3 189 1.5E-57 T 31-10-2018 TK1517 3d980e5923e2e150f02cbb053fbbb8ef 196 Pfam PF13207 AAA domain 8 144 4.2E-36 T 31-10-2018 TK1517 3d980e5923e2e150f02cbb053fbbb8ef 196 Hamap MF_00234 Adenylate kinase [adkA]. 3 189 44.62 T 31-10-2018 IPR023477 Adenylate kinase AdkA GO:0004017 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 TK1517 3d980e5923e2e150f02cbb053fbbb8ef 196 SUPERFAMILY SSF52540 1 188 7.13E-22 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK1536 3f84ec0d4da58658399e4dc9f1ed46ba 209 SUPERFAMILY SSF54821 86 186 3.53E-26 T 31-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1536 3f84ec0d4da58658399e4dc9f1ed46ba 209 Pfam PF07650 KH domain 17 88 1.7E-15 T 31-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1536 3f84ec0d4da58658399e4dc9f1ed46ba 209 SMART SM00322 38 104 2.7E-8 T 31-10-2018 IPR004087 K Homology domain GO:0003676 TK1536 3f84ec0d4da58658399e4dc9f1ed46ba 209 Hamap MF_01309_A 30S ribosomal protein S3 [rpsC]. 2 197 42.868 T 31-10-2018 IPR027488 Ribosomal protein S3, archaeal GO:0003735|GO:0006412|GO:0015935 TK1536 3f84ec0d4da58658399e4dc9f1ed46ba 209 Gene3D G3DSA:3.30.300.20 1 86 1.4E-30 T 31-10-2018 IPR015946 K homology domain-like, alpha/beta TK1536 3f84ec0d4da58658399e4dc9f1ed46ba 209 SUPERFAMILY SSF54814 7 93 6.8E-26 T 31-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 TK1536 3f84ec0d4da58658399e4dc9f1ed46ba 209 Gene3D G3DSA:3.30.1140.32 87 209 7.0E-42 T 31-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1536 3f84ec0d4da58658399e4dc9f1ed46ba 209 TIGRFAM TIGR01008 uS3_euk_arch: ribosomal protein uS3 3 197 4.6E-95 T 31-10-2018 IPR005703 Ribosomal protein S3, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1536 3f84ec0d4da58658399e4dc9f1ed46ba 209 Pfam PF00189 Ribosomal protein S3, C-terminal domain 99 182 3.2E-24 T 31-10-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1102 ac9dd6e9b4a7bf71b48a20cdcf9cee14 267 Pfam PF09754 PAC2 family 19 242 5.4E-50 T 31-10-2018 IPR019151 Proteasome assembly chaperone 2 TK1102 ac9dd6e9b4a7bf71b48a20cdcf9cee14 267 TIGRFAM TIGR00162 TIGR00162: TIGR00162 family protein 12 266 3.2E-74 T 31-10-2018 IPR004426 Conserved hypothetical protein CHP00062 TK1102 ac9dd6e9b4a7bf71b48a20cdcf9cee14 267 Gene3D G3DSA:3.40.50.10900 1 244 9.1E-77 T 31-10-2018 IPR038389 Proteasome assembly chaperone 2 superfamily TK1102 ac9dd6e9b4a7bf71b48a20cdcf9cee14 267 SUPERFAMILY SSF159659 2 259 7.19E-47 T 31-10-2018 TK1387 4cd97be7ca8c5d4403e71a6666abacf2 234 Pfam PF13367 Protease prsW family 31 203 7.5E-31 T 31-10-2018 IPR026898 Protease PrsW GO:0008233 TK1387 4cd97be7ca8c5d4403e71a6666abacf2 234 PIRSF PIRSF016933 4 225 7.0E-34 T 31-10-2018 IPR023596 Peptidase PrsW, archaeal/bacterial GO:0008233 TK1386 3b685a8b1a8e10e87fb94b9fe31f1d65 225 Gene3D G3DSA:3.60.21.10 15 165 3.4E-11 T 31-10-2018 IPR029052 Metallo-dependent phosphatase-like TK1386 3b685a8b1a8e10e87fb94b9fe31f1d65 225 TIGRFAM TIGR00024 SbcD_rel_arch: putative phosphoesterase 7 219 3.9E-50 T 31-10-2018 IPR004376 Conserved hypothetical protein CHP00024, phosphoesterase-like TK1386 3b685a8b1a8e10e87fb94b9fe31f1d65 225 Pfam PF00149 Calcineurin-like phosphoesterase 17 112 3.4E-8 T 31-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 TK1386 3b685a8b1a8e10e87fb94b9fe31f1d65 225 SUPERFAMILY SSF56300 17 140 4.01E-15 T 31-10-2018 TK1386 3b685a8b1a8e10e87fb94b9fe31f1d65 225 PIRSF PIRSF000887 4 223 1.4E-59 T 31-10-2018 IPR024173 Phosphoesterase, MJ0037 TK1141 8726cdffed6c959557577bd8f49dabfa 246 Pfam PF00633 Helix-hairpin-helix motif 119 148 1.2E-6 T 31-10-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 TK1141 8726cdffed6c959557577bd8f49dabfa 246 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 208 224 - T 31-10-2018 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 TK1141 8726cdffed6c959557577bd8f49dabfa 246 Hamap MF_00942 Endonuclease III [nth]. 20 230 33.734 T 31-10-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 TK1141 8726cdffed6c959557577bd8f49dabfa 246 SUPERFAMILY SSF48150 24 228 4.71E-63 T 31-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 TK1141 8726cdffed6c959557577bd8f49dabfa 246 PIRSF PIRSF001435 18 232 9.7E-44 T 31-10-2018 TK1141 8726cdffed6c959557577bd8f49dabfa 246 Gene3D G3DSA:1.10.1670.10 36 224 7.2E-66 T 31-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 TK1141 8726cdffed6c959557577bd8f49dabfa 246 Gene3D G3DSA:1.10.340.30 39 152 7.2E-66 T 31-10-2018 TK1141 8726cdffed6c959557577bd8f49dabfa 246 Pfam PF10576 Iron-sulfur binding domain of endonuclease III 208 224 2.8E-4 T 31-10-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 TK1141 8726cdffed6c959557577bd8f49dabfa 246 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 52 189 2.5E-17 T 31-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 TK1141 8726cdffed6c959557577bd8f49dabfa 246 SMART SM00525 207 227 8.9E-7 T 31-10-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 TK1141 8726cdffed6c959557577bd8f49dabfa 246 SMART SM00478 56 206 2.1E-58 T 31-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 TK1141 8726cdffed6c959557577bd8f49dabfa 246 ProSitePatterns PS01155 Endonuclease III family signature. 122 151 - T 31-10-2018 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 TK0347 af398c9bdbaa6da9b5de39d1bd9712d4 447 SUPERFAMILY SSF141322 374 443 7.59E-19 T 31-10-2018 TK0347 af398c9bdbaa6da9b5de39d1bd9712d4 447 Gene3D G3DSA:3.90.226.10 22 245 1.2E-64 T 31-10-2018 TK0347 af398c9bdbaa6da9b5de39d1bd9712d4 447 Gene3D G3DSA:2.40.50.140 379 447 1.1E-24 T 31-10-2018 TK0347 af398c9bdbaa6da9b5de39d1bd9712d4 447 SUPERFAMILY SSF52096 10 193 7.26E-30 T 31-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TK0347 af398c9bdbaa6da9b5de39d1bd9712d4 447 Pfam PF00574 Clp protease 34 191 2.7E-6 T 31-10-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA TK0347 af398c9bdbaa6da9b5de39d1bd9712d4 447 Pfam PF01957 NfeD-like C-terminal, partner-binding 297 442 2.8E-37 T 31-10-2018 IPR002810 NfeD-like, C-terminal domain TK1846 9f8e1d911ca42af10ac15ec6b022f02f 317 PIRSF PIRSF002849 1 316 1.6E-139 T 31-10-2018 TK1846 9f8e1d911ca42af10ac15ec6b022f02f 317 Gene3D G3DSA:3.40.50.300 21 187 1.7E-47 T 31-10-2018 TK1846 9f8e1d911ca42af10ac15ec6b022f02f 317 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 40 170 2.3E-67 T 31-10-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 TK1846 9f8e1d911ca42af10ac15ec6b022f02f 317 SUPERFAMILY SSF52540 15 288 6.97E-48 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK1846 9f8e1d911ca42af10ac15ec6b022f02f 317 Gene3D G3DSA:1.10.8.300 202 311 2.7E-38 T 31-10-2018 TK0059 44eebdf6839d4d3e53969cc1ec4a107b 189 Pfam PF01066 CDP-alcohol phosphatidyltransferase 25 89 1.7E-15 T 31-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 TK0059 44eebdf6839d4d3e53969cc1ec4a107b 189 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 67 89 - T 31-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 TK0059 44eebdf6839d4d3e53969cc1ec4a107b 189 Gene3D G3DSA:1.20.120.1760 6 189 3.5E-49 T 31-10-2018 TK0657 884bd8ae2c412f562df4226f29542506 430 Gene3D G3DSA:3.40.50.2300 260 387 1.7E-42 T 31-10-2018 TK0657 884bd8ae2c412f562df4226f29542506 430 Gene3D G3DSA:3.40.50.2300 26 147 2.2E-27 T 31-10-2018 TK0657 884bd8ae2c412f562df4226f29542506 430 Pfam PF02608 ABC transporter substrate-binding protein PnrA-like 32 172 1.5E-17 T 31-10-2018 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 TK0657 884bd8ae2c412f562df4226f29542506 430 Pfam PF02608 ABC transporter substrate-binding protein PnrA-like 270 418 5.0E-30 T 31-10-2018 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 TK0109 20602d55832f079d25739b9832894317 337 Pfam PF11536 Protein of unknown function (DUF3226) 100 335 1.9E-102 T 31-10-2018 IPR024508 Protein of unknown function DUF3226 TK0109 20602d55832f079d25739b9832894317 337 Gene3D G3DSA:1.10.3490.10 234 320 1.9E-79 T 31-10-2018 TK0109 20602d55832f079d25739b9832894317 337 ProDom PD038575 MJECL12 PLASMID PH0156 100 321 1.0E-125 T 31-10-2018 IPR024508 Protein of unknown function DUF3226 TK0109 20602d55832f079d25739b9832894317 337 SUPERFAMILY SSF160945 99 333 1.2E-90 T 31-10-2018 TK0109 20602d55832f079d25739b9832894317 337 Gene3D G3DSA:3.40.50.10620 100 233 1.9E-79 T 31-10-2018 TK0119 16a482158f40025d6a1190d90ca78b5e 483 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 118 425 2.7E-38 T 31-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TK0119 16a482158f40025d6a1190d90ca78b5e 483 SUPERFAMILY SSF51905 111 432 1.3E-42 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TK0119 16a482158f40025d6a1190d90ca78b5e 483 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 60 68 - T 31-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 TK0119 16a482158f40025d6a1190d90ca78b5e 483 Gene3D G3DSA:3.50.50.60 118 440 1.8E-60 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TK0119 16a482158f40025d6a1190d90ca78b5e 483 SUPERFAMILY SSF54292 17 96 5.37E-23 T 31-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 TK0119 16a482158f40025d6a1190d90ca78b5e 483 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 15 95 3.2E-30 T 31-10-2018 TK0119 16a482158f40025d6a1190d90ca78b5e 483 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 228 237 9.4E-22 T 31-10-2018 TK0119 16a482158f40025d6a1190d90ca78b5e 483 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 406 413 9.4E-22 T 31-10-2018 TK0119 16a482158f40025d6a1190d90ca78b5e 483 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 269 294 9.4E-22 T 31-10-2018 TK0119 16a482158f40025d6a1190d90ca78b5e 483 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 360 374 9.4E-22 T 31-10-2018 TK0119 16a482158f40025d6a1190d90ca78b5e 483 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 118 140 9.4E-22 T 31-10-2018 TK0119 16a482158f40025d6a1190d90ca78b5e 483 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 359 375 2.7E-27 T 31-10-2018 TK0119 16a482158f40025d6a1190d90ca78b5e 483 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 391 413 2.7E-27 T 31-10-2018 TK0119 16a482158f40025d6a1190d90ca78b5e 483 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 269 287 2.7E-27 T 31-10-2018 TK0119 16a482158f40025d6a1190d90ca78b5e 483 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 225 243 2.7E-27 T 31-10-2018 TK0119 16a482158f40025d6a1190d90ca78b5e 483 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 119 138 2.7E-27 T 31-10-2018 TK0119 16a482158f40025d6a1190d90ca78b5e 483 Gene3D G3DSA:3.10.20.440 5 100 4.4E-34 T 31-10-2018 TK0119 16a482158f40025d6a1190d90ca78b5e 483 Gene3D G3DSA:3.50.50.60 237 367 1.8E-60 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TK1723 7f32db94f64d30683b575ceab3d00cd8 388 Gene3D G3DSA:3.40.50.2000 194 371 2.6E-50 T 31-10-2018 TK1723 7f32db94f64d30683b575ceab3d00cd8 388 SUPERFAMILY SSF53756 20 384 3.93E-54 T 31-10-2018 TK1723 7f32db94f64d30683b575ceab3d00cd8 388 Pfam PF00534 Glycosyl transferases group 1 204 365 5.3E-27 T 31-10-2018 IPR001296 Glycosyl transferase, family 1 TK1723 7f32db94f64d30683b575ceab3d00cd8 388 Pfam PF13439 Glycosyltransferase Family 4 25 198 8.3E-12 T 31-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 TK1723 7f32db94f64d30683b575ceab3d00cd8 388 Gene3D G3DSA:3.40.50.2000 32 378 2.6E-50 T 31-10-2018 TK0429 c260d68841422e477f748251320c8efc 156 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 15 149 6.3E-50 T 31-10-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TK0429 c260d68841422e477f748251320c8efc 156 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 15 150 7.9E-54 T 31-10-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TK0429 c260d68841422e477f748251320c8efc 156 Gene3D G3DSA:3.40.50.960 3 153 2.2E-58 T 31-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TK0429 c260d68841422e477f748251320c8efc 156 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 11 152 30.207 T 31-10-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TK0429 c260d68841422e477f748251320c8efc 156 SUPERFAMILY SSF52121 6 154 4.84E-57 T 31-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TK2102 3c5c0d8f41b49d1c38f006c42249e364 199 Gene3D G3DSA:1.10.1760.20 33 194 2.2E-48 T 31-10-2018 TK2102 3c5c0d8f41b49d1c38f006c42249e364 199 Pfam PF07155 ECF-type riboflavin transporter, S component 36 190 3.7E-44 T 31-10-2018 IPR009825 ECF transporter, substrate-specific component-like GO:0016020 TK0110 b3c7e962ba5d6c60b8523e0923a8ed58 246 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 159 179 2.3E-6 T 31-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TK0110 b3c7e962ba5d6c60b8523e0923a8ed58 246 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 107 120 2.3E-6 T 31-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TK0110 b3c7e962ba5d6c60b8523e0923a8ed58 246 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 1 12 2.3E-6 T 31-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TK0110 b3c7e962ba5d6c60b8523e0923a8ed58 246 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 141 157 2.3E-6 T 31-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TK0110 b3c7e962ba5d6c60b8523e0923a8ed58 246 Gene3D G3DSA:3.40.50.1000 90 229 2.3E-33 T 31-10-2018 IPR023214 HAD superfamily TK0110 b3c7e962ba5d6c60b8523e0923a8ed58 246 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 137 192 8.7E-6 T 31-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TK0110 b3c7e962ba5d6c60b8523e0923a8ed58 246 SUPERFAMILY SSF56784 1 226 1.65E-34 T 31-10-2018 IPR036412 HAD-like superfamily TK0110 b3c7e962ba5d6c60b8523e0923a8ed58 246 Pfam PF00702 haloacid dehalogenase-like hydrolase 1 188 1.6E-11 T 31-10-2018 TK0110 b3c7e962ba5d6c60b8523e0923a8ed58 246 Gene3D G3DSA:1.10.150.400 14 89 9.4E-26 T 31-10-2018 TK1259 c1c6c19353778629b8b6153e1a45ab1d 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 22 33 6.1E-12 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TK1259 c1c6c19353778629b8b6153e1a45ab1d 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 6 22 6.1E-12 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TK1259 c1c6c19353778629b8b6153e1a45ab1d 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 33 52 6.1E-12 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TK1259 c1c6c19353778629b8b6153e1a45ab1d 150 SUPERFAMILY SSF46785 6 77 2.24E-14 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TK1259 c1c6c19353778629b8b6153e1a45ab1d 150 Gene3D G3DSA:3.30.70.920 58 150 1.0E-28 T 31-10-2018 TK1259 c1c6c19353778629b8b6153e1a45ab1d 150 SUPERFAMILY SSF54909 67 148 1.61E-5 T 31-10-2018 IPR011008 Dimeric alpha-beta barrel TK1259 c1c6c19353778629b8b6153e1a45ab1d 150 SMART SM00344 9 112 2.1E-20 T 31-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 TK1259 c1c6c19353778629b8b6153e1a45ab1d 150 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 37 52 3.6E-5 T 31-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 TK1259 c1c6c19353778629b8b6153e1a45ab1d 150 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 21 37 3.6E-5 T 31-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 TK1259 c1c6c19353778629b8b6153e1a45ab1d 150 Pfam PF13412 Winged helix-turn-helix DNA-binding 7 52 1.9E-15 T 31-10-2018 TK1259 c1c6c19353778629b8b6153e1a45ab1d 150 Gene3D G3DSA:1.10.10.10 2 57 8.9E-20 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TK1414 4ba0c76c5109b349b7cf921cb1cca588 155 TIGRFAM TIGR02274 dCTP_deam: deoxycytidine triphosphate deaminase 9 152 3.7E-45 T 31-10-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 TK1414 4ba0c76c5109b349b7cf921cb1cca588 155 Pfam PF00692 dUTPase 41 138 3.8E-15 T 31-10-2018 IPR029054 dUTPase-like TK1414 4ba0c76c5109b349b7cf921cb1cca588 155 Gene3D G3DSA:2.70.40.10 1 155 1.3E-42 T 31-10-2018 IPR036157 dUTPase-like superfamily TK1414 4ba0c76c5109b349b7cf921cb1cca588 155 SUPERFAMILY SSF51283 1 152 5.76E-40 T 31-10-2018 IPR036157 dUTPase-like superfamily TK1414 4ba0c76c5109b349b7cf921cb1cca588 155 Hamap MF_00146 dCTP deaminase [dcd]. 1 153 27.261 T 31-10-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 TK0970 e3c03b5d85a145ce7d524663e35eb97b 376 Gene3D G3DSA:3.30.56.70 317 376 3.7E-21 T 31-10-2018 TK0970 e3c03b5d85a145ce7d524663e35eb97b 376 Gene3D G3DSA:3.40.50.150 1 316 1.7E-105 T 31-10-2018 TK0970 e3c03b5d85a145ce7d524663e35eb97b 376 TIGRFAM TIGR00308 TRM1: N2,N2-dimethylguanosine tRNA methyltransferase 6 375 2.2E-97 T 31-10-2018 IPR002905 tRNA methyltransferase, Trm1 GO:0003723|GO:0004809|GO:0008033 MetaCyc: PWY-6829 TK0970 e3c03b5d85a145ce7d524663e35eb97b 376 Pfam PF02005 N2,N2-dimethylguanosine tRNA methyltransferase 10 374 1.8E-116 T 31-10-2018 IPR002905 tRNA methyltransferase, Trm1 GO:0003723|GO:0004809|GO:0008033 MetaCyc: PWY-6829 TK0970 e3c03b5d85a145ce7d524663e35eb97b 376 SUPERFAMILY SSF53335 4 374 2.61E-111 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TK0970 e3c03b5d85a145ce7d524663e35eb97b 376 Hamap MF_00290 tRNA (guanine(26)-N(2))-dimethyltransferase [trm1]. 4 375 43.898 T 31-10-2018 IPR022923 tRNA (guanine(26)-N(2))-dimethyltransferase, archaeal and bacterial GO:0004809 MetaCyc: PWY-6829 TK0898 264dd19351bdcee83def40522ddc67dd 168 SUPERFAMILY SSF47240 16 166 3.48E-7 T 31-10-2018 IPR009078 Ferritin-like superfamily TK0898 264dd19351bdcee83def40522ddc67dd 168 Gene3D G3DSA:1.20.1260.10 13 166 9.4E-13 T 31-10-2018 IPR012347 Ferritin-like TK0802 6aa5fa65ac59ea2db3a88986f12f44bc 117 TIGRFAM TIGR00523 eIF-1A: translation initiation factor eIF-1A 13 105 4.3E-36 T 31-10-2018 IPR001253 Translation initiation factor 1A (eIF-1A) GO:0003743|GO:0006413 TK0802 6aa5fa65ac59ea2db3a88986f12f44bc 117 ProDom PD005579 INITIATION FACTOR TRANSLATION 1A BIOSYNTHESIS EUKARYOTIC EIF-1A AIF-1A EIF-4C 1A 48 105 9.0E-27 T 31-10-2018 IPR001253 Translation initiation factor 1A (eIF-1A) GO:0003743|GO:0006413 TK0802 6aa5fa65ac59ea2db3a88986f12f44bc 117 SMART SM00652 23 106 1.4E-42 T 31-10-2018 IPR001253 Translation initiation factor 1A (eIF-1A) GO:0003743|GO:0006413 TK0802 6aa5fa65ac59ea2db3a88986f12f44bc 117 Gene3D G3DSA:2.40.50.140 3 117 1.1E-38 T 31-10-2018 TK0802 6aa5fa65ac59ea2db3a88986f12f44bc 117 ProSitePatterns PS01262 Eukaryotic initiation factor 1A signature. 36 58 - T 31-10-2018 IPR018104 Translation initiation factor 1A (eIF-1A), conserved site GO:0003743|GO:0006413 TK0802 6aa5fa65ac59ea2db3a88986f12f44bc 117 SUPERFAMILY SSF50249 3 109 2.06E-32 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold TK0802 6aa5fa65ac59ea2db3a88986f12f44bc 117 Hamap MF_00216 Translation initiation factor 1A [eif1a]. 10 106 28.384 T 31-10-2018 IPR001253 Translation initiation factor 1A (eIF-1A) GO:0003743|GO:0006413 TK0802 6aa5fa65ac59ea2db3a88986f12f44bc 117 Pfam PF01176 Translation initiation factor 1A / IF-1 27 90 2.6E-20 T 31-10-2018 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 TK1091 6119dad666936060aee714795c6dbf67 1229 Pfam PF14528 LAGLIDADG-like domain 618 700 2.8E-14 T 31-10-2018 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 TK1091 6119dad666936060aee714795c6dbf67 1229 SMART SM00305 786 832 1.5E-14 T 31-10-2018 IPR003586 Hint domain C-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TK1091 6119dad666936060aee714795c6dbf67 1229 SMART SM00437 271 1038 4.2E-101 T 31-10-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 TK1091 6119dad666936060aee714795c6dbf67 1229 SUPERFAMILY SSF55608 606 717 4.25E-16 T 31-10-2018 IPR027434 Homing endonuclease TK1091 6119dad666936060aee714795c6dbf67 1229 SMART SM00436 131 226 8.8E-42 T 31-10-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 TK1091 6119dad666936060aee714795c6dbf67 1229 Hamap MF_00952 DNA topoisomerase 1 [topA]. 2 1219 44.033 T 31-10-2018 IPR028612 DNA topoisomerase I, type IA GO:0003677|GO:0003916|GO:0006265 TK1091 6119dad666936060aee714795c6dbf67 1229 Gene3D G3DSA:2.170.16.10 317 422 6.2E-12 T 31-10-2018 TK1091 6119dad666936060aee714795c6dbf67 1229 SUPERFAMILY SSF56712 2 316 6.28E-84 T 31-10-2018 IPR023405 DNA topoisomerase, type IA, core domain TK1091 6119dad666936060aee714795c6dbf67 1229 TIGRFAM TIGR01445 intein_Nterm: intein N-terminal splicing region 316 387 1.2E-7 T 31-10-2018 IPR006141 Intein N-terminal splicing region GO:0016539 Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TK1091 6119dad666936060aee714795c6dbf67 1229 Pfam PF01751 Toprim domain 3 139 1.2E-17 T 31-10-2018 IPR006171 TOPRIM domain TK1091 6119dad666936060aee714795c6dbf67 1229 Gene3D G3DSA:2.60.510.20 915 984 6.0E-56 T 31-10-2018 TK1091 6119dad666936060aee714795c6dbf67 1229 Gene3D G3DSA:2.60.510.20 218 280 2.1E-37 T 31-10-2018 TK1091 6119dad666936060aee714795c6dbf67 1229 Gene3D G3DSA:3.10.28.10 522 693 6.3E-18 T 31-10-2018 IPR027434 Homing endonuclease TK1091 6119dad666936060aee714795c6dbf67 1229 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 1149 1187 7.6E-14 T 31-10-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 TK1091 6119dad666936060aee714795c6dbf67 1229 SUPERFAMILY SSF55608 522 606 2.76E-8 T 31-10-2018 IPR027434 Homing endonuclease TK1091 6119dad666936060aee714795c6dbf67 1229 Gene3D G3DSA:1.10.460.10 985 1077 6.0E-56 T 31-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 TK1091 6119dad666936060aee714795c6dbf67 1229 Gene3D G3DSA:1.10.460.10 161 217 2.1E-37 T 31-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 TK1091 6119dad666936060aee714795c6dbf67 1229 SUPERFAMILY SSF57783 1136 1189 3.57E-6 T 31-10-2018 TK1091 6119dad666936060aee714795c6dbf67 1229 Pfam PF14890 Intein splicing domain 330 826 1.1E-28 T 31-10-2018 TK1091 6119dad666936060aee714795c6dbf67 1229 TIGRFAM TIGR01057 topA_arch: DNA topoisomerase I 6 319 1.2E-149 T 31-10-2018 IPR005739 DNA topoisomerase I, archeal-type GO:0003677|GO:0003916|GO:0006265 TK1091 6119dad666936060aee714795c6dbf67 1229 Pfam PF01131 DNA topoisomerase 156 315 1.2E-50 T 31-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 TK1091 6119dad666936060aee714795c6dbf67 1229 Pfam PF01131 DNA topoisomerase 827 1075 6.0E-75 T 31-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 TK1091 6119dad666936060aee714795c6dbf67 1229 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 196 214 2.1E-22 T 31-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 TK1091 6119dad666936060aee714795c6dbf67 1229 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 1002 1016 2.1E-22 T 31-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 TK1091 6119dad666936060aee714795c6dbf67 1229 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 103 116 2.1E-22 T 31-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 TK1091 6119dad666936060aee714795c6dbf67 1229 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 903 919 2.1E-22 T 31-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 TK1091 6119dad666936060aee714795c6dbf67 1229 SMART SM00306 314 411 1.4E-24 T 31-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TK1091 6119dad666936060aee714795c6dbf67 1229 Gene3D G3DSA:1.10.290.10 281 315 2.1E-37 T 31-10-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 TK1091 6119dad666936060aee714795c6dbf67 1229 Gene3D G3DSA:1.10.290.10 828 914 6.0E-56 T 31-10-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 TK1091 6119dad666936060aee714795c6dbf67 1229 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 805 827 6.3E-9 T 31-10-2018 IPR030934 Intein C-terminal splicing region TK1091 6119dad666936060aee714795c6dbf67 1229 PRINTS PR00379 Intein signature 803 820 5.6E-14 T 31-10-2018 IPR006142 Intein GO:0016539 TK1091 6119dad666936060aee714795c6dbf67 1229 PRINTS PR00379 Intein signature 821 830 5.6E-14 T 31-10-2018 IPR006142 Intein GO:0016539 TK1091 6119dad666936060aee714795c6dbf67 1229 PRINTS PR00379 Intein signature 374 387 5.6E-14 T 31-10-2018 IPR006142 Intein GO:0016539 TK1091 6119dad666936060aee714795c6dbf67 1229 PRINTS PR00379 Intein signature 525 537 5.6E-14 T 31-10-2018 IPR006142 Intein GO:0016539 TK1091 6119dad666936060aee714795c6dbf67 1229 PRINTS PR00379 Intein signature 619 631 5.6E-14 T 31-10-2018 IPR006142 Intein GO:0016539 TK1091 6119dad666936060aee714795c6dbf67 1229 SUPERFAMILY SSF51294 316 826 4.12E-39 T 31-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TK1091 6119dad666936060aee714795c6dbf67 1229 SMART SM00493 2 129 1.5E-19 T 31-10-2018 IPR006171 TOPRIM domain TK1091 6119dad666936060aee714795c6dbf67 1229 Gene3D G3DSA:2.170.16.10 707 825 2.4E-12 T 31-10-2018 TK1091 6119dad666936060aee714795c6dbf67 1229 SUPERFAMILY SSF56712 827 1162 5.62E-74 T 31-10-2018 IPR023405 DNA topoisomerase, type IA, core domain TK1091 6119dad666936060aee714795c6dbf67 1229 Gene3D G3DSA:3.40.50.140 1 154 2.3E-30 T 31-10-2018 TK2076 1f009abfc30f12f10ce137bf4ad0171d 721 SUPERFAMILY SSF53706 13 590 1.2E-209 T 31-10-2018 TK2076 1f009abfc30f12f10ce137bf4ad0171d 721 Gene3D G3DSA:2.40.40.20 576 705 8.2E-45 T 31-10-2018 TK2076 1f009abfc30f12f10ce137bf4ad0171d 721 Gene3D G3DSA:3.40.228.10 151 349 1.2E-184 T 31-10-2018 TK2076 1f009abfc30f12f10ce137bf4ad0171d 721 SMART SM00926 14 71 2.4E-10 T 31-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TK2076 1f009abfc30f12f10ce137bf4ad0171d 721 Gene3D G3DSA:2.20.25.90 15 70 2.3E-10 T 31-10-2018 TK2076 1f009abfc30f12f10ce137bf4ad0171d 721 Pfam PF00384 Molybdopterin oxidoreductase 74 495 2.6E-93 T 31-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TK2076 1f009abfc30f12f10ce137bf4ad0171d 721 Pfam PF01568 Molydopterin dinucleotide binding domain 588 691 9.0E-32 T 31-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 TK2076 1f009abfc30f12f10ce137bf4ad0171d 721 Gene3D G3DSA:3.40.50.740 83 545 1.2E-184 T 31-10-2018 TK2076 1f009abfc30f12f10ce137bf4ad0171d 721 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 15 69 1.4E-9 T 31-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TK2076 1f009abfc30f12f10ce137bf4ad0171d 721 PIRSF PIRSF000144 63 441 5.1E-64 T 31-10-2018 TK2076 1f009abfc30f12f10ce137bf4ad0171d 721 PIRSF PIRSF000144 551 701 2.8E-4 T 31-10-2018 TK2076 1f009abfc30f12f10ce137bf4ad0171d 721 TIGRFAM TIGR01591 Fdh-alpha: formate dehydrogenase, alpha subunit 19 694 3.2E-245 T 31-10-2018 IPR006478 Formate dehydrogenase, alpha subunit GO:0008863|GO:0015942|GO:0055114 KEGG: 00630+1.17.1.9|KEGG: 00680+1.17.1.9|MetaCyc: PWY-1881|MetaCyc: PWY-5497|MetaCyc: PWY-6696|MetaCyc: PWY-7985 TK2076 1f009abfc30f12f10ce137bf4ad0171d 721 SUPERFAMILY SSF50692 549 696 1.53E-50 T 31-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily TK2128 7d9b19617828f31fb0c6ab613e49e9f4 165 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 8 70 2.3E-13 T 31-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 TK2128 7d9b19617828f31fb0c6ab613e49e9f4 165 Gene3D G3DSA:3.40.50.620 6 154 6.7E-42 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TK2128 7d9b19617828f31fb0c6ab613e49e9f4 165 Hamap MF_00647 Phosphopantetheine adenylyltransferase [coaD]. 6 156 33.559 T 31-10-2018 IPR023540 Phosphopantetheine adenylyltransferase, archaea GO:0004595 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 TK2128 7d9b19617828f31fb0c6ab613e49e9f4 165 Pfam PF01467 Cytidylyltransferase-like 9 145 2.6E-17 T 31-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 TK2128 7d9b19617828f31fb0c6ab613e49e9f4 165 SUPERFAMILY SSF52374 3 147 2.45E-21 T 31-10-2018 TK1118 058d28e6b89f808c34a833156ce02115 155 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 4 144 9.727 T 31-10-2018 IPR022907 VapC family GO:0004540 TK1118 058d28e6b89f808c34a833156ce02115 155 Gene3D G3DSA:3.40.50.1010 3 150 4.7E-12 T 31-10-2018 TK1118 058d28e6b89f808c34a833156ce02115 155 SUPERFAMILY SSF88723 1 138 3.64E-20 T 31-10-2018 IPR029060 PIN-like domain superfamily TK1118 058d28e6b89f808c34a833156ce02115 155 SMART SM00670 2 135 1.7E-7 T 31-10-2018 IPR002716 PIN domain TK1118 058d28e6b89f808c34a833156ce02115 155 Pfam PF01850 PIN domain 5 136 1.9E-19 T 31-10-2018 IPR002716 PIN domain TK0816 1d170b38f2b511627c4e3cd5bf00676b 294 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 61 204 3.3E-32 T 31-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 TK0816 1d170b38f2b511627c4e3cd5bf00676b 294 Gene3D G3DSA:3.40.50.970 79 220 3.7E-26 T 31-10-2018 TK0816 1d170b38f2b511627c4e3cd5bf00676b 294 SUPERFAMILY SSF52518 20 278 1.2E-80 T 31-10-2018 IPR029061 Thiamin diphosphate-binding fold TK0816 1d170b38f2b511627c4e3cd5bf00676b 294 Pfam PF12367 Pyruvate ferredoxin oxidoreductase beta subunit C terminal 208 269 1.0E-25 T 31-10-2018 IPR032686 Pyruvate ferredoxin oxidoreductase beta subunit, C-terminal TK0816 1d170b38f2b511627c4e3cd5bf00676b 294 TIGRFAM TIGR02177 PorB_KorB: 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate family 23 282 3.0E-111 T 31-10-2018 IPR011896 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate TK0333 5eb425fd40988e476943d4a1d0219a9b 228 Gene3D G3DSA:2.40.100.10 85 225 3.5E-64 T 31-10-2018 IPR029000 Cyclophilin-like domain superfamily TK0333 5eb425fd40988e476943d4a1d0219a9b 228 TIGRFAM TIGR00370 TIGR00370: sensor histidine kinase inhibitor, KipI family 6 209 5.7E-70 T 31-10-2018 IPR010016 KipI family KEGG: 00480+3.5.2.9|MetaCyc: PWY-4041|MetaCyc: PWY-7942 TK0333 5eb425fd40988e476943d4a1d0219a9b 228 SMART SM00796 1 200 1.6E-111 T 31-10-2018 IPR003833 Carboxyltransferase domain, subdomain C and D TK0333 5eb425fd40988e476943d4a1d0219a9b 228 SUPERFAMILY SSF160467 3 90 9.29E-22 T 31-10-2018 TK0333 5eb425fd40988e476943d4a1d0219a9b 228 Gene3D G3DSA:3.30.1360.40 1 84 9.1E-26 T 31-10-2018 TK0333 5eb425fd40988e476943d4a1d0219a9b 228 SUPERFAMILY SSF50891 86 216 2.84E-51 T 31-10-2018 IPR029000 Cyclophilin-like domain superfamily TK0333 5eb425fd40988e476943d4a1d0219a9b 228 Pfam PF02682 Carboxyltransferase domain, subdomain C and D 2 200 3.9E-77 T 31-10-2018 IPR003833 Carboxyltransferase domain, subdomain C and D TK0547 130e2d8864b041a206e25337a57c235b 218 Gene3D G3DSA:3.60.21.10 1 214 2.3E-45 T 31-10-2018 IPR029052 Metallo-dependent phosphatase-like TK0547 130e2d8864b041a206e25337a57c235b 218 SUPERFAMILY SSF56300 1 207 1.21E-71 T 31-10-2018 TK0547 130e2d8864b041a206e25337a57c235b 218 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 1 205 1.8E-21 T 31-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 TK1473 5b9994c354d87f264ec5f1a4a829981e 262 Gene3D G3DSA:3.40.1160.10 1 261 1.0E-59 T 31-10-2018 IPR036393 Acetylglutamate kinase-like superfamily TK1473 5b9994c354d87f264ec5f1a4a829981e 262 Pfam PF00696 Amino acid kinase family 2 233 1.1E-38 T 31-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 TK1473 5b9994c354d87f264ec5f1a4a829981e 262 SUPERFAMILY SSF53633 2 261 8.51E-35 T 31-10-2018 IPR036393 Acetylglutamate kinase-like superfamily TK1473 5b9994c354d87f264ec5f1a4a829981e 262 PIRSF PIRSF016496 1 262 3.1E-82 T 31-10-2018 IPR024192 Fosfomycin resistance kinase, FomA-type GO:0016301 KEGG: 00900+2.7.4.26|MetaCyc: PWY-6174|MetaCyc: PWY-7524 TK0154 5108678c7d7798cf9333cbce05f3d399 96 SUPERFAMILY SSF111057 5 93 1.44E-33 T 31-10-2018 IPR036216 Hypothetical protein UCP004604 superfamily TK0154 5108678c7d7798cf9333cbce05f3d399 96 Pfam PF08967 Domain of unknown function (DUF1884) 6 96 2.7E-42 T 31-10-2018 IPR014418 Uncharacterised conserved protein UCP004604 TK0154 5108678c7d7798cf9333cbce05f3d399 96 Gene3D G3DSA:3.30.2320.10 2 96 3.6E-26 T 31-10-2018 TK0154 5108678c7d7798cf9333cbce05f3d399 96 PIRSF PIRSF004604 3 96 2.1E-20 T 31-10-2018 IPR014418 Uncharacterised conserved protein UCP004604 TK0154 5108678c7d7798cf9333cbce05f3d399 96 ProDom PD029791 ORF 3'REGION GAP PF1875 PF0899 PH1831 B PHS036 6 95 1.0E-33 T 31-10-2018 IPR014418 Uncharacterised conserved protein UCP004604 TK0366 37a06d022de6a245e5c5a6e1d828d924 191 SUPERFAMILY SSF52402 2 156 5.95E-41 T 31-10-2018 TK0366 37a06d022de6a245e5c5a6e1d828d924 191 Gene3D G3DSA:3.40.50.620 1 191 7.8E-59 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TK0366 37a06d022de6a245e5c5a6e1d828d924 191 Pfam PF02568 Thiamine biosynthesis protein (ThiI) 2 188 1.5E-57 T 31-10-2018 IPR020536 Thil, AANH domain GO:0004810 KEGG: 00730+2.8.1.4 TK2259 9da4f2e170f4797c213ac343ba412fdf 121 Gene3D G3DSA:1.10.10.10 19 85 6.4E-15 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TK2259 9da4f2e170f4797c213ac343ba412fdf 121 SUPERFAMILY SSF46785 17 116 2.19E-17 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TK2259 9da4f2e170f4797c213ac343ba412fdf 121 Pfam PF03965 Penicillinase repressor 19 112 1.9E-17 T 31-10-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 TK0701 e4e6624e19009342fec3226dd5e2cdb9 296 Pfam PF14697 4Fe-4S dicluster domain 64 118 2.2E-11 T 31-10-2018 TK0701 e4e6624e19009342fec3226dd5e2cdb9 296 Gene3D G3DSA:3.30.70.20 51 132 6.8E-15 T 31-10-2018 TK0701 e4e6624e19009342fec3226dd5e2cdb9 296 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 71 82 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TK0701 e4e6624e19009342fec3226dd5e2cdb9 296 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 3 266 9.6E-22 T 31-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain TK0701 e4e6624e19009342fec3226dd5e2cdb9 296 SUPERFAMILY SSF54862 54 122 5.18E-18 T 31-10-2018 TK0701 e4e6624e19009342fec3226dd5e2cdb9 296 SUPERFAMILY SSF52540 1 293 2.72E-35 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK0701 e4e6624e19009342fec3226dd5e2cdb9 296 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 101 112 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TK0460 d0f0b0f00462ec278bff0f110fd20c61 740 TIGRFAM TIGR01587 cas3_core: CRISPR-associated helicase Cas3 250 598 3.0E-97 T 31-10-2018 IPR006474 Helicase Cas3, CRISPR-associated, core TK0460 d0f0b0f00462ec278bff0f110fd20c61 740 Gene3D G3DSA:3.40.50.300 434 594 9.4E-13 T 31-10-2018 TK0460 d0f0b0f00462ec278bff0f110fd20c61 740 SUPERFAMILY SSF109604 47 106 1.81E-6 T 31-10-2018 TK0460 d0f0b0f00462ec278bff0f110fd20c61 740 SMART SM00490 482 561 3.1E-8 T 31-10-2018 IPR001650 Helicase, C-terminal TK0460 d0f0b0f00462ec278bff0f110fd20c61 740 Gene3D G3DSA:3.40.50.300 218 429 3.7E-17 T 31-10-2018 TK0460 d0f0b0f00462ec278bff0f110fd20c61 740 Pfam PF00270 DEAD/DEAH box helicase 246 415 7.2E-14 T 31-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 TK0460 d0f0b0f00462ec278bff0f110fd20c61 740 TIGRFAM TIGR01596 cas3_HD: CRISPR-associated endonuclease Cas3-HD 14 212 1.3E-28 T 31-10-2018 IPR006483 CRISPR-associated Cas3-type HD domain TK0460 d0f0b0f00462ec278bff0f110fd20c61 740 Gene3D G3DSA:1.10.3210.30 1 160 5.2E-17 T 31-10-2018 IPR038257 CRISPR-associated Cas3-type HD domain superfamily TK0460 d0f0b0f00462ec278bff0f110fd20c61 740 SMART SM00487 232 444 2.2E-13 T 31-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TK0460 d0f0b0f00462ec278bff0f110fd20c61 740 Pfam PF00271 Helicase conserved C-terminal domain 463 561 2.2E-6 T 31-10-2018 IPR001650 Helicase, C-terminal TK0460 d0f0b0f00462ec278bff0f110fd20c61 740 SUPERFAMILY SSF52540 245 563 4.99E-33 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK0524 5a0acb3ad47f8795f0120c5b39ef6f79 53 PRINTS PR00163 Rubredoxin signature 3 19 4.0E-12 T 31-10-2018 IPR024935 Rubredoxin domain GO:0005506 TK0524 5a0acb3ad47f8795f0120c5b39ef6f79 53 PRINTS PR00163 Rubredoxin signature 33 49 4.0E-12 T 31-10-2018 IPR024935 Rubredoxin domain GO:0005506 TK0524 5a0acb3ad47f8795f0120c5b39ef6f79 53 SUPERFAMILY SSF57802 1 53 2.36E-25 T 31-10-2018 TK0524 5a0acb3ad47f8795f0120c5b39ef6f79 53 Pfam PF00301 Rubredoxin 3 49 3.2E-26 T 31-10-2018 IPR024935 Rubredoxin domain GO:0005506 TK0524 5a0acb3ad47f8795f0120c5b39ef6f79 53 Gene3D G3DSA:2.20.28.10 2 53 3.1E-30 T 31-10-2018 TK0524 5a0acb3ad47f8795f0120c5b39ef6f79 53 ProSitePatterns PS00202 Rubredoxin signature. 33 43 - T 31-10-2018 IPR018527 Rubredoxin, iron-binding site GO:0046872 TK0524 5a0acb3ad47f8795f0120c5b39ef6f79 53 PIRSF PIRSF000071 1 53 1.7E-29 T 31-10-2018 IPR024922 Rubredoxin GO:0005506|GO:0009055 TK1472 d70b3bbb8f47d441b0f86086bdb68b39 251 SMART SM00852 4 179 4.5E-41 T 31-10-2018 IPR001453 MoaB/Mog domain TK1472 d70b3bbb8f47d441b0f86086bdb68b39 251 Pfam PF00994 Probable molybdopterin binding domain 4 176 4.2E-36 T 31-10-2018 IPR001453 MoaB/Mog domain TK1472 d70b3bbb8f47d441b0f86086bdb68b39 251 SUPERFAMILY SSF53218 1 206 1.96E-40 T 31-10-2018 IPR036425 MoaB/Mog-like domain superfamily TK1472 d70b3bbb8f47d441b0f86086bdb68b39 251 Gene3D G3DSA:3.40.980.10 2 179 9.7E-54 T 31-10-2018 IPR036425 MoaB/Mog-like domain superfamily TK1472 d70b3bbb8f47d441b0f86086bdb68b39 251 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 3 174 2.1E-25 T 31-10-2018 IPR001453 MoaB/Mog domain TK1472 d70b3bbb8f47d441b0f86086bdb68b39 251 Hamap MF_00226_A Putative competence-damage inducible protein [cinA]. 1 249 38.539 T 31-10-2018 IPR023055 Putative competence-damage inducible protein, Archaea TK1543 c8c1eb0585cef8b731eaa813adda731c 256 Gene3D G3DSA:3.40.1280.10 5 252 5.0E-77 T 31-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal TK1543 c8c1eb0585cef8b731eaa813adda731c 256 SUPERFAMILY SSF75217 4 254 3.66E-47 T 31-10-2018 IPR029028 Alpha/beta knot methyltransferases TK1543 c8c1eb0585cef8b731eaa813adda731c 256 Gene3D G3DSA:2.40.50.140 91 156 5.0E-77 T 31-10-2018 TK1543 c8c1eb0585cef8b731eaa813adda731c 256 Pfam PF02598 Putative RNA methyltransferase 5 249 1.5E-50 T 31-10-2018 IPR003750 Putative RNA methyltransferase TK1543 c8c1eb0585cef8b731eaa813adda731c 256 SUPERFAMILY SSF50249 91 156 5.65E-12 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold TK1397 a1ede3146c7fd629accf79315d253561 248 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 12 212 8.0E-36 T 31-10-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 TK1397 a1ede3146c7fd629accf79315d253561 248 SUPERFAMILY SSF51695 6 214 9.63E-61 T 31-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 TK1397 a1ede3146c7fd629accf79315d253561 248 Gene3D G3DSA:3.20.20.190 1 248 8.8E-105 T 31-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 TK1208 7791f3b9e2dcce52e801c939ad1eb7e9 194 Pfam PF00462 Glutaredoxin 55 112 4.2E-5 T 31-10-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 TK1208 7791f3b9e2dcce52e801c939ad1eb7e9 194 Gene3D G3DSA:3.40.30.10 40 124 3.5E-8 T 31-10-2018 TK1208 7791f3b9e2dcce52e801c939ad1eb7e9 194 SUPERFAMILY SSF52833 50 128 4.84E-11 T 31-10-2018 IPR036249 Thioredoxin-like superfamily TK0029 0f2b5efc314683990c6c8f94fc0ff014 292 SUPERFAMILY SSF56281 6 277 1.54E-34 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TK0029 0f2b5efc314683990c6c8f94fc0ff014 292 Gene3D G3DSA:3.60.15.10 1 225 1.2E-25 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TK0029 0f2b5efc314683990c6c8f94fc0ff014 292 Pfam PF00753 Metallo-beta-lactamase superfamily 16 196 6.7E-10 T 31-10-2018 IPR001279 Metallo-beta-lactamase TK0029 0f2b5efc314683990c6c8f94fc0ff014 292 SMART SM00849 15 200 4.0E-10 T 31-10-2018 IPR001279 Metallo-beta-lactamase TK0683 8c1a9cbbbd4343fdc69891fd668f132f 333 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 5 322 3.3E-37 T 31-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 TK0683 8c1a9cbbbd4343fdc69891fd668f132f 333 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 153 180 - T 31-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 TK0683 8c1a9cbbbd4343fdc69891fd668f132f 333 SUPERFAMILY SSF52283 2 133 5.29E-43 T 31-10-2018 TK0683 8c1a9cbbbd4343fdc69891fd668f132f 333 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 230 246 - T 31-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site TK0683 8c1a9cbbbd4343fdc69891fd668f132f 333 SUPERFAMILY SSF51735 103 290 6.4E-66 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily TK0683 8c1a9cbbbd4343fdc69891fd668f132f 333 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 110 290 3.2E-68 T 31-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 TK0683 8c1a9cbbbd4343fdc69891fd668f132f 333 Gene3D G3DSA:3.40.50.720 4 317 5.6E-143 T 31-10-2018 TK0683 8c1a9cbbbd4343fdc69891fd668f132f 333 Gene3D G3DSA:3.40.50.720 98 290 5.6E-143 T 31-10-2018 TK0683 8c1a9cbbbd4343fdc69891fd668f132f 333 Hamap MF_00776 Glyoxylate reductase [gyaR]. 1 331 61.56 T 31-10-2018 IPR023519 Glyoxylate reductase GyaR GO:0047964|GO:0055114 KEGG: 00630+1.1.1.26|MetaCyc: PWY-7294|MetaCyc: PWY-7295 TK0858 0fdc2b14f293e8c86a83a2b8b65ab0d0 137 Pfam PF04608 Phosphatidylglycerophosphatase A 15 133 9.3E-9 T 31-10-2018 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 TK0858 0fdc2b14f293e8c86a83a2b8b65ab0d0 137 SUPERFAMILY SSF101307 6 134 3.4E-34 T 31-10-2018 IPR036681 PgpA-like superfamily GO:0006629|GO:0008962 TK0858 0fdc2b14f293e8c86a83a2b8b65ab0d0 137 TIGRFAM TIGR03161 ribazole_CobZ: alpha-ribazole phosphatase CobZ 8 134 2.8E-55 T 31-10-2018 IPR017577 Alpha-ribazole phosphatase, CobZ TK0858 0fdc2b14f293e8c86a83a2b8b65ab0d0 137 Gene3D G3DSA:1.10.3760.10 2 136 4.1E-11 T 31-10-2018 TK1967 3d5d61fbf13ac81a83db1437bc061689 215 TIGRFAM TIGR00153 TIGR00153: TIGR00153 family protein 16 214 3.6E-39 T 31-10-2018 IPR002727 Protein of unknown function DUF47 TK1967 3d5d61fbf13ac81a83db1437bc061689 215 SUPERFAMILY SSF109755 12 209 5.23E-10 T 31-10-2018 TK1967 3d5d61fbf13ac81a83db1437bc061689 215 Gene3D G3DSA:1.20.58.220 2 212 1.8E-48 T 31-10-2018 IPR038078 PhoU-like domain superfamily TK1967 3d5d61fbf13ac81a83db1437bc061689 215 Pfam PF01865 Protein of unknown function DUF47 7 211 7.0E-41 T 31-10-2018 IPR018445 Putative phosphate transport regulator TK1410 aa42372a93218e1f83bc68e510b9a431 464 Pfam PF13662 Toprim domain 199 282 4.0E-13 T 31-10-2018 IPR006171 TOPRIM domain TK1410 aa42372a93218e1f83bc68e510b9a431 464 Hamap MF_00007 DNA primase DnaG [dnaG]. 34 463 36.569 T 31-10-2018 IPR020607 DNA primase DnaG, archaea GO:0000178|GO:0003896|GO:0008143 TK1410 aa42372a93218e1f83bc68e510b9a431 464 Gene3D G3DSA:3.40.1360.10 196 292 9.0E-13 T 31-10-2018 TK1410 aa42372a93218e1f83bc68e510b9a431 464 SUPERFAMILY SSF56731 197 295 1.05E-10 T 31-10-2018 TK1410 aa42372a93218e1f83bc68e510b9a431 464 SMART SM00493 198 267 1.3E-12 T 31-10-2018 IPR006171 TOPRIM domain TK0035 d1e788df85a75de8478b00428e75206b 425 SMART SM00564 189 230 28.0 T 31-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat TK0035 d1e788df85a75de8478b00428e75206b 425 SMART SM00564 48 93 23.0 T 31-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat TK0035 d1e788df85a75de8478b00428e75206b 425 SMART SM00564 320 367 53.0 T 31-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat TK0035 d1e788df85a75de8478b00428e75206b 425 SMART SM00564 279 313 270.0 T 31-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat TK0035 d1e788df85a75de8478b00428e75206b 425 SMART SM00564 137 182 450.0 T 31-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat TK0035 d1e788df85a75de8478b00428e75206b 425 TIGRFAM TIGR04288 CGP_CTERM: CGP-CTERM domain 405 424 1.8E-4 T 31-10-2018 IPR027552 CGP-CTERM domain TK0035 d1e788df85a75de8478b00428e75206b 425 Gene3D G3DSA:2.130.10.10 21 396 1.3E-21 T 31-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 TK0035 d1e788df85a75de8478b00428e75206b 425 SUPERFAMILY SSF50998 55 412 5.96E-15 T 31-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily TK0035 d1e788df85a75de8478b00428e75206b 425 Pfam PF13570 PQQ-like domain 306 359 1.4E-7 T 31-10-2018 IPR025666 Pyrrolo-quinoline quinone-like domain TK2247 07fb2a9bf1897c475c9adf790bc82553 391 Gene3D G3DSA:1.20.1250.20 2 384 1.8E-51 T 31-10-2018 TK2247 07fb2a9bf1897c475c9adf790bc82553 391 Pfam PF07690 Major Facilitator Superfamily 13 321 1.3E-38 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TK2247 07fb2a9bf1897c475c9adf790bc82553 391 PRINTS PR01035 Tetracycline resistance protein signature 17 33 5.4E-6 T 31-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 TK2247 07fb2a9bf1897c475c9adf790bc82553 391 PRINTS PR01035 Tetracycline resistance protein signature 299 319 5.4E-6 T 31-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 TK2247 07fb2a9bf1897c475c9adf790bc82553 391 PRINTS PR01035 Tetracycline resistance protein signature 135 157 5.4E-6 T 31-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 TK2247 07fb2a9bf1897c475c9adf790bc82553 391 SUPERFAMILY SSF103473 6 385 1.09E-57 T 31-10-2018 IPR036259 MFS transporter superfamily TK0568 f921d3efed6f359f0cde255d0d80719a 375 SUPERFAMILY SSF52374 2 363 1.31E-66 T 31-10-2018 TK0568 f921d3efed6f359f0cde255d0d80719a 375 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 4 360 4.9E-35 T 31-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 TK0568 f921d3efed6f359f0cde255d0d80719a 375 PIRSF PIRSF006588 1 375 4.3E-131 T 31-10-2018 IPR023617 Tyrosine-tRNA ligase, archaeal/eukaryotic-type GO:0004831 KEGG: 00970+6.1.1.1 TK0568 f921d3efed6f359f0cde255d0d80719a 375 Pfam PF00579 tRNA synthetases class I (W and Y) 33 352 2.4E-44 T 31-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 TK0568 f921d3efed6f359f0cde255d0d80719a 375 Hamap MF_02009 Tyrosine--tRNA ligase [tyrS]. 5 359 47.855 T 31-10-2018 IPR023678 Tyrosine-tRNA ligase, type 4 GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 TK0568 f921d3efed6f359f0cde255d0d80719a 375 Gene3D G3DSA:1.10.240.10 227 375 1.1E-56 T 31-10-2018 TK0568 f921d3efed6f359f0cde255d0d80719a 375 Gene3D G3DSA:3.40.50.620 1 226 9.6E-61 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TK0540 748be66ca9a24ed7116609dd122f5d71 419 SUPERFAMILY SSF109604 6 414 2.27E-93 T 31-10-2018 TK0540 748be66ca9a24ed7116609dd122f5d71 419 Gene3D G3DSA:1.10.3210.10 8 330 6.8E-85 T 31-10-2018 TK0540 748be66ca9a24ed7116609dd122f5d71 419 SMART SM00471 53 191 1.3E-13 T 31-10-2018 IPR003607 HD/PDEase domain TK0540 748be66ca9a24ed7116609dd122f5d71 419 Pfam PF01966 HD domain 57 147 1.7E-14 T 31-10-2018 IPR006674 HD domain TK0506 0daa1ac69d0d501ee6c3eb82ec4c0de6 397 Gene3D G3DSA:1.10.8.470 126 215 1.5E-30 T 31-10-2018 TK0506 0daa1ac69d0d501ee6c3eb82ec4c0de6 397 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 92 110 4.7E-31 T 31-10-2018 IPR006073 GTP binding domain GO:0005525 TK0506 0daa1ac69d0d501ee6c3eb82ec4c0de6 397 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 75 90 4.7E-31 T 31-10-2018 IPR006073 GTP binding domain GO:0005525 TK0506 0daa1ac69d0d501ee6c3eb82ec4c0de6 397 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 24 42 4.7E-31 T 31-10-2018 IPR006073 GTP binding domain GO:0005525 TK0506 0daa1ac69d0d501ee6c3eb82ec4c0de6 397 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 3 23 4.7E-31 T 31-10-2018 IPR006073 GTP binding domain GO:0005525 TK0506 0daa1ac69d0d501ee6c3eb82ec4c0de6 397 SUPERFAMILY SSF81271 322 393 1.05E-18 T 31-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 TK0506 0daa1ac69d0d501ee6c3eb82ec4c0de6 397 Pfam PF02824 TGS domain 341 393 1.0E-13 T 31-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 TK0506 0daa1ac69d0d501ee6c3eb82ec4c0de6 397 Pfam PF01926 50S ribosome-binding GTPase 2 132 2.0E-19 T 31-10-2018 IPR006073 GTP binding domain GO:0005525 TK0506 0daa1ac69d0d501ee6c3eb82ec4c0de6 397 SUPERFAMILY SSF52540 1 315 5.19E-73 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK0506 0daa1ac69d0d501ee6c3eb82ec4c0de6 397 Gene3D G3DSA:3.10.20.30 319 397 3.5E-32 T 31-10-2018 IPR012675 Beta-grasp domain superfamily TK0506 0daa1ac69d0d501ee6c3eb82ec4c0de6 397 Pfam PF08438 GTPase of unknown function C-terminal 220 327 6.9E-36 T 31-10-2018 IPR013646 Uncharacterised GTP-binding protein, C-terminal TK0280 b0e2de425cbc03c255d1a2329bcb6496 347 TIGRFAM TIGR02088 LEU3_arch: isopropylmalate/isohomocitrate dehydrogenases 4 316 2.9E-124 T 31-10-2018 IPR011828 Isopropylmalate/isohomocitrate dehydrogenase GO:0003862|GO:0009098|GO:0051287|GO:0055114 TK0280 b0e2de425cbc03c255d1a2329bcb6496 347 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 214 233 - T 31-10-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 TK0280 b0e2de425cbc03c255d1a2329bcb6496 347 SMART SM01329 3 315 3.3E-135 T 31-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 TK0280 b0e2de425cbc03c255d1a2329bcb6496 347 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 4 310 3.9E-84 T 31-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 TK0280 b0e2de425cbc03c255d1a2329bcb6496 347 Gene3D G3DSA:3.40.718.10 1 332 1.5E-142 T 31-10-2018 TK0280 b0e2de425cbc03c255d1a2329bcb6496 347 SUPERFAMILY SSF53659 2 317 9.9E-101 T 31-10-2018 TK2029 b530cb933a64aa899ce6cc49e21ae45a 294 SUPERFAMILY SSF53613 3 277 4.37E-64 T 31-10-2018 IPR029056 Ribokinase-like TK2029 b530cb933a64aa899ce6cc49e21ae45a 294 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 226 239 - T 31-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 TK2029 b530cb933a64aa899ce6cc49e21ae45a 294 Gene3D G3DSA:3.40.1190.20 1 283 2.0E-63 T 31-10-2018 IPR029056 Ribokinase-like TK2029 b530cb933a64aa899ce6cc49e21ae45a 294 PRINTS PR00990 Ribokinase signature 34 53 5.0E-9 T 31-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 TK2029 b530cb933a64aa899ce6cc49e21ae45a 294 PRINTS PR00990 Ribokinase signature 197 208 5.0E-9 T 31-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 TK2029 b530cb933a64aa899ce6cc49e21ae45a 294 PRINTS PR00990 Ribokinase signature 165 180 5.0E-9 T 31-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 TK2029 b530cb933a64aa899ce6cc49e21ae45a 294 PRINTS PR00990 Ribokinase signature 7 28 5.0E-9 T 31-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 TK2029 b530cb933a64aa899ce6cc49e21ae45a 294 PRINTS PR00990 Ribokinase signature 104 117 5.0E-9 T 31-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 TK2029 b530cb933a64aa899ce6cc49e21ae45a 294 Pfam PF00294 pfkB family carbohydrate kinase 5 271 1.8E-44 T 31-10-2018 IPR011611 Carbohydrate kinase PfkB TK1940 a79f1fbcacff7522672b5999fb5a7834 358 Gene3D G3DSA:3.30.70.100 250 342 3.7E-29 T 31-10-2018 TK1940 a79f1fbcacff7522672b5999fb5a7834 358 Pfam PF00924 Mechanosensitive ion channel 139 338 2.0E-59 T 31-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 TK1940 a79f1fbcacff7522672b5999fb5a7834 358 SUPERFAMILY SSF50182 184 248 9.48E-18 T 31-10-2018 IPR010920 LSM domain superfamily TK1940 a79f1fbcacff7522672b5999fb5a7834 358 SUPERFAMILY SSF82689 252 348 2.48E-32 T 31-10-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 TK1940 a79f1fbcacff7522672b5999fb5a7834 358 SUPERFAMILY SSF82861 99 182 4.45E-8 T 31-10-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 TK1940 a79f1fbcacff7522672b5999fb5a7834 358 Gene3D G3DSA:2.30.30.60 199 248 7.6E-14 T 31-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily TK1529 f6a31fff768adba7ed216a33b02e6284 243 Gene3D G3DSA:2.30.30.30 179 243 4.0E-19 T 31-10-2018 IPR014722 Ribosomal protein L2, domain 2 TK1529 f6a31fff768adba7ed216a33b02e6284 243 Pfam PF08071 RS4NT (NUC023) domain 4 39 2.2E-17 T 31-10-2018 IPR013843 Ribosomal protein S4e, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1529 f6a31fff768adba7ed216a33b02e6284 243 PIRSF PIRSF002116 2 243 1.3E-101 T 31-10-2018 IPR000876 Ribosomal protein S4e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1529 f6a31fff768adba7ed216a33b02e6284 243 ProSitePatterns PS00528 Ribosomal protein S4e signature. 9 23 - T 31-10-2018 IPR018199 Ribosomal protein S4e, N-terminal, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1529 f6a31fff768adba7ed216a33b02e6284 243 Gene3D G3DSA:2.40.50.740 123 177 2.2E-17 T 31-10-2018 IPR038237 Ribosomal protein S4e, central domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1529 f6a31fff768adba7ed216a33b02e6284 243 SMART SM00363 43 107 1.4E-9 T 31-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1529 f6a31fff768adba7ed216a33b02e6284 243 ProDom PD002667 RIBOSOMAL RIBONUCLEOPROTEIN RNA-BINDING 40S S4 S4 S4E 30S ISOFORM X 88 182 3.0E-40 T 31-10-2018 IPR013845 Ribosomal protein S4e, central region Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1529 f6a31fff768adba7ed216a33b02e6284 243 SUPERFAMILY SSF55174 52 96 1.83E-7 T 31-10-2018 TK1529 f6a31fff768adba7ed216a33b02e6284 243 Pfam PF01479 S4 domain 52 91 5.3E-13 T 31-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1529 f6a31fff768adba7ed216a33b02e6284 243 Hamap MF_00485 30S ribosomal protein S4e [rps4e]. 8 242 43.267 T 31-10-2018 IPR000876 Ribosomal protein S4e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1529 f6a31fff768adba7ed216a33b02e6284 243 Gene3D G3DSA:3.10.290.40 1 118 5.7E-51 T 31-10-2018 TK1529 f6a31fff768adba7ed216a33b02e6284 243 Pfam PF00900 Ribosomal family S4e 96 173 3.1E-24 T 31-10-2018 IPR013845 Ribosomal protein S4e, central region Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK0005 27a043cbd3fdc3b7da8aacabf9ecc9fa 142 Pfam PF13380 CoA binding domain 23 137 1.6E-40 T 31-10-2018 IPR003781 CoA-binding GO:0048037 TK0005 27a043cbd3fdc3b7da8aacabf9ecc9fa 142 Gene3D G3DSA:3.40.50.720 4 142 7.9E-51 T 31-10-2018 TK0005 27a043cbd3fdc3b7da8aacabf9ecc9fa 142 SMART SM00881 18 111 3.8E-31 T 31-10-2018 IPR003781 CoA-binding GO:0048037 TK0005 27a043cbd3fdc3b7da8aacabf9ecc9fa 142 SUPERFAMILY SSF51735 7 139 6.04E-46 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily TK0096 76f7f8195419031eeb5df7f7de434972 914 Gene3D G3DSA:1.10.10.10 837 911 9.3E-11 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TK0096 76f7f8195419031eeb5df7f7de434972 914 Pfam PF17207 MCM OB domain 334 467 7.1E-22 T 31-10-2018 IPR033762 MCM OB domain Reactome: R-HSA-176187|Reactome: R-HSA-176974|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962 TK0096 76f7f8195419031eeb5df7f7de434972 914 Gene3D G3DSA:2.20.28.10 366 417 1.0E-27 T 31-10-2018 TK0096 76f7f8195419031eeb5df7f7de434972 914 Pfam PF14551 MCM N-terminal domain 236 326 2.8E-10 T 31-10-2018 IPR027925 MCM N-terminal domain Reactome: R-HSA-176187|Reactome: R-HSA-176974|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962|Reactome: R-HSA-69052 TK0096 76f7f8195419031eeb5df7f7de434972 914 Gene3D G3DSA:3.30.1640.10 228 328 1.7E-25 T 31-10-2018 TK0096 76f7f8195419031eeb5df7f7de434972 914 SUPERFAMILY SSF50249 237 483 3.43E-39 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold TK0096 76f7f8195419031eeb5df7f7de434972 914 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 614 628 5.3E-13 T 31-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 TK0096 76f7f8195419031eeb5df7f7de434972 914 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 642 655 5.3E-13 T 31-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 TK0096 76f7f8195419031eeb5df7f7de434972 914 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 666 678 5.3E-13 T 31-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 TK0096 76f7f8195419031eeb5df7f7de434972 914 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 556 571 5.3E-13 T 31-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 TK0096 76f7f8195419031eeb5df7f7de434972 914 Pfam PF00493 MCM2/3/5 family 504 817 3.4E-69 T 31-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 TK0096 76f7f8195419031eeb5df7f7de434972 914 SMART SM00350 329 818 8.1E-38 T 31-10-2018 IPR031327 Mini-chromosome maintenance protein TK0096 76f7f8195419031eeb5df7f7de434972 914 Gene3D G3DSA:3.40.50.300 500 821 8.1E-79 T 31-10-2018 TK0096 76f7f8195419031eeb5df7f7de434972 914 Gene3D G3DSA:2.40.50.140 336 486 1.0E-27 T 31-10-2018 TK0096 76f7f8195419031eeb5df7f7de434972 914 SUPERFAMILY SSF52540 526 819 3.49E-33 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK1319 e430814196abdd9b15a4795aafd35552 51 Hamap MF_00629 50S ribosomal protein L39e [rpl39e]. 1 51 19.338 T 31-10-2018 IPR000077 Ribosomal protein L39e GO:0003735|GO:0005622|GO:0005840|GO:0006412 TK1319 e430814196abdd9b15a4795aafd35552 51 ProSitePatterns PS00051 Ribosomal protein L39e signature. 30 46 - T 31-10-2018 IPR020083 Ribosomal protein L39e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1319 e430814196abdd9b15a4795aafd35552 51 Gene3D G3DSA:1.10.1620.10 2 51 2.1E-20 T 31-10-2018 IPR023626 Ribosomal protein L39e domain superfamily TK1319 e430814196abdd9b15a4795aafd35552 51 SUPERFAMILY SSF48662 4 50 6.41E-20 T 31-10-2018 IPR023626 Ribosomal protein L39e domain superfamily TK1319 e430814196abdd9b15a4795aafd35552 51 Pfam PF00832 Ribosomal L39 protein 9 50 9.0E-23 T 31-10-2018 IPR000077 Ribosomal protein L39e GO:0003735|GO:0005622|GO:0005840|GO:0006412 TK0431 7d10f9852d93d111f410521e229449eb 310 Pfam PF06849 Protein of unknown function (DUF1246) 3 113 1.2E-33 T 31-10-2018 IPR010672 IMP biosynthesis enzyme PurP, N-terminal GO:0000287|GO:0005524|GO:0006188|GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 TK0431 7d10f9852d93d111f410521e229449eb 310 SUPERFAMILY SSF56059 99 310 7.77E-69 T 31-10-2018 TK0431 7d10f9852d93d111f410521e229449eb 310 Gene3D G3DSA:3.30.470.20 85 308 3.2E-81 T 31-10-2018 TK0431 7d10f9852d93d111f410521e229449eb 310 SUPERFAMILY SSF52440 3 95 1.25E-30 T 31-10-2018 IPR016185 Pre-ATP-grasp domain superfamily TK0431 7d10f9852d93d111f410521e229449eb 310 Gene3D G3DSA:3.40.50.20 1 83 8.3E-32 T 31-10-2018 TK0431 7d10f9852d93d111f410521e229449eb 310 PIRSF PIRSF004602 1 310 2.2E-100 T 31-10-2018 IPR023656 IMP biosynthesis enzyme PurP GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 TK0431 7d10f9852d93d111f410521e229449eb 310 Pfam PF06973 Domain of unknown function (DUF1297) 158 310 1.3E-41 T 31-10-2018 IPR009720 IMP biosynthesis enzyme PurP, C-terminal GO:0000287|GO:0005524|GO:0006188|GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 TK0431 7d10f9852d93d111f410521e229449eb 310 Gene3D G3DSA:3.30.1490.20 112 165 3.2E-81 T 31-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 TK1773 10f0a6d2a0d20b5017ce0b892efa3981 414 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 219 400 1.2E-16 T 31-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TK1773 10f0a6d2a0d20b5017ce0b892efa3981 414 SUPERFAMILY SSF161098 7 67 1.19E-5 T 31-10-2018 IPR035906 MetI-like superfamily TK1773 10f0a6d2a0d20b5017ce0b892efa3981 414 Gene3D G3DSA:1.10.3720.10 2 76 1.8E-7 T 31-10-2018 IPR035906 MetI-like superfamily TK1773 10f0a6d2a0d20b5017ce0b892efa3981 414 SUPERFAMILY SSF161098 175 413 2.35E-54 T 31-10-2018 IPR035906 MetI-like superfamily TK1773 10f0a6d2a0d20b5017ce0b892efa3981 414 Gene3D G3DSA:1.10.3720.10 160 401 3.5E-48 T 31-10-2018 IPR035906 MetI-like superfamily TK2272 518a23ed31234385de32b36a9ee9fd86 256 PIRSF PIRSF009320 2 47 3.6E-14 T 31-10-2018 TK2272 518a23ed31234385de32b36a9ee9fd86 256 PIRSF PIRSF009320 91 256 6.8E-7 T 31-10-2018 TK2272 518a23ed31234385de32b36a9ee9fd86 256 SUPERFAMILY SSF52540 1 254 1.02E-59 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK2272 518a23ed31234385de32b36a9ee9fd86 256 Gene3D G3DSA:3.40.50.300 1 255 9.0E-75 T 31-10-2018 TK2272 518a23ed31234385de32b36a9ee9fd86 256 Pfam PF13614 AAA domain 4 178 1.2E-53 T 31-10-2018 IPR025669 AAA domain TK0122 0a241c3ac7fcc755af93ff7c71bce3a9 385 Gene3D G3DSA:3.50.50.60 8 359 9.7E-136 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TK0122 0a241c3ac7fcc755af93ff7c71bce3a9 385 SUPERFAMILY SSF54373 222 315 2.62E-8 T 31-10-2018 TK0122 0a241c3ac7fcc755af93ff7c71bce3a9 385 SUPERFAMILY SSF51905 6 375 6.47E-61 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TK0122 0a241c3ac7fcc755af93ff7c71bce3a9 385 Gene3D G3DSA:3.30.9.10 86 314 9.7E-136 T 31-10-2018 TK0122 0a241c3ac7fcc755af93ff7c71bce3a9 385 Pfam PF01266 FAD dependent oxidoreductase 7 354 1.5E-73 T 31-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 TK0086 17744cb85b940dcd7329e0e2843b0fd8 191 SUPERFAMILY SSF46785 105 181 4.12E-9 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TK0086 17744cb85b940dcd7329e0e2843b0fd8 191 Pfam PF01022 Bacterial regulatory protein, arsR family 107 149 4.4E-5 T 31-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TK0086 17744cb85b940dcd7329e0e2843b0fd8 191 Gene3D G3DSA:1.10.10.10 105 164 1.0E-5 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TK1552 86cc809af233a8d478657c1b500d3495 753 Pfam PF10131 6-pyruvoyl-tetrahydropterin synthase related domain; membrane protein 62 622 3.2E-151 T 31-10-2018 IPR018776 Membrane protein, 6-pyruvoyl-tetrahydropterin synthase-related domain TK1635 37dcd424b83d77df03d2ff3494b7b4d6 257 SUPERFAMILY SSF110324 3 58 2.88E-13 T 31-10-2018 TK1635 37dcd424b83d77df03d2ff3494b7b4d6 257 Hamap MF_00623 Exosome complex component Rrp4 [rrp4]. 7 232 40.263 T 31-10-2018 IPR023474 Exosome complex component Rrp4 GO:0000178|GO:0008143 TK1635 37dcd424b83d77df03d2ff3494b7b4d6 257 SMART SM00322 146 211 7.2E-8 T 31-10-2018 IPR004087 K Homology domain GO:0003676 TK1635 37dcd424b83d77df03d2ff3494b7b4d6 257 SUPERFAMILY SSF50249 59 152 3.77E-18 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold TK1635 37dcd424b83d77df03d2ff3494b7b4d6 257 Pfam PF14382 Exosome complex exonuclease RRP4 N-terminal region 11 46 1.1E-6 T 31-10-2018 IPR025721 Exosome complex component, N-terminal domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TK1635 37dcd424b83d77df03d2ff3494b7b4d6 257 Pfam PF15985 KH domain 149 195 8.4E-10 T 31-10-2018 IPR004088 K Homology domain, type 1 GO:0003723 TK1635 37dcd424b83d77df03d2ff3494b7b4d6 257 SUPERFAMILY SSF54791 148 226 9.76E-18 T 31-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 TK1635 37dcd424b83d77df03d2ff3494b7b4d6 257 Gene3D G3DSA:2.40.50.140 58 142 1.1E-21 T 31-10-2018 TK1635 37dcd424b83d77df03d2ff3494b7b4d6 257 Gene3D G3DSA:2.40.50.100 1 57 2.1E-22 T 31-10-2018 TK1635 37dcd424b83d77df03d2ff3494b7b4d6 257 Gene3D G3DSA:3.30.1370.10 149 234 6.8E-34 T 31-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 TK1635 37dcd424b83d77df03d2ff3494b7b4d6 257 SMART SM00316 63 137 8.6E-9 T 31-10-2018 IPR022967 RNA-binding domain, S1 TK1848 b4efb18493c23da8effa1868e639bf68 278 Pfam PF13559 Domain of unknown function (DUF4129) 201 262 4.1E-7 T 31-10-2018 IPR025403 Domain of unknown function DUF4129 TK0015 62bf53b4d71396e7acef03ad909eb03f 354 Gene3D G3DSA:3.40.190.10 124 292 1.4E-129 T 31-10-2018 TK0015 62bf53b4d71396e7acef03ad909eb03f 354 Pfam PF13531 Bacterial extracellular solute-binding protein 40 322 3.6E-32 T 31-10-2018 TK0015 62bf53b4d71396e7acef03ad909eb03f 354 SUPERFAMILY SSF53850 35 343 2.34E-50 T 31-10-2018 TK0015 62bf53b4d71396e7acef03ad909eb03f 354 TIGRFAM TIGR03730 tungstate_WtpA: tungstate ABC transporter binding protein WtpA 37 310 1.6E-122 T 31-10-2018 IPR022498 Tungstate ABC transporter, substrate-binding protein WtpA GO:1901359 TK0015 62bf53b4d71396e7acef03ad909eb03f 354 Gene3D G3DSA:3.40.190.10 38 341 1.4E-129 T 31-10-2018 TK1191 104e424d48787a45e778b4db56e75261 130 Pfam PF01201 Ribosomal protein S8e 2 125 1.5E-33 T 31-10-2018 IPR022309 Ribosomal protein S8e/ribosomal biogenesis NSA2 TK1191 104e424d48787a45e778b4db56e75261 130 TIGRFAM TIGR00307 eS8: ribosomal protein eS8 1 127 3.7E-48 T 31-10-2018 IPR001047 Ribosomal protein S8e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1191 104e424d48787a45e778b4db56e75261 130 ProSitePatterns PS01193 Ribosomal protein S8e signature. 10 29 - T 31-10-2018 IPR018283 Ribosomal protein S8e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1191 104e424d48787a45e778b4db56e75261 130 Gene3D G3DSA:2.40.10.310 61 130 1.8E-32 T 31-10-2018 TK1191 104e424d48787a45e778b4db56e75261 130 Hamap MF_00029 30S ribosomal protein S8e [rps8e]. 2 126 32.497 T 31-10-2018 IPR020919 Ribosomal protein S8e, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 TK1098 5d79b9170ea1b9f9c3b52155c244b15f 94 ProDom PD002841 RIBOSOMAL RIBONUCLEOPROTEIN 60S L44 L44E L41 RESISTANCE 50S ANTIBIOTIC CYCLOHEXIMIDE 9 93 6.0E-43 T 31-10-2018 IPR000552 Ribosomal protein L44e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1098 5d79b9170ea1b9f9c3b52155c244b15f 94 ProSitePatterns PS01172 Ribosomal protein L44e signature. 60 71 - T 31-10-2018 IPR000552 Ribosomal protein L44e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1098 5d79b9170ea1b9f9c3b52155c244b15f 94 Pfam PF00935 Ribosomal protein L44 16 92 2.0E-26 T 31-10-2018 IPR000552 Ribosomal protein L44e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1098 5d79b9170ea1b9f9c3b52155c244b15f 94 Gene3D G3DSA:3.10.450.80 1 93 4.3E-31 T 31-10-2018 TK1098 5d79b9170ea1b9f9c3b52155c244b15f 94 SUPERFAMILY SSF57829 1 93 2.87E-29 T 31-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 TK1098 5d79b9170ea1b9f9c3b52155c244b15f 94 Hamap MF_01476 50S ribosomal protein L44e [rpl44e]. 1 92 25.054 T 31-10-2018 IPR000552 Ribosomal protein L44e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1291 718cd581634759a99b5445bb160be5e1 75 SUPERFAMILY SSF89447 4 56 4.84E-7 T 31-10-2018 IPR037914 SpoVT-AbrB domain superfamily TK1291 718cd581634759a99b5445bb160be5e1 75 SMART SM00966 7 48 2.6E-5 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 TK1291 718cd581634759a99b5445bb160be5e1 75 Pfam PF02381 MraZ protein, putative antitoxin-like 1 44 3.4E-5 T 31-10-2018 IPR020603 MraZ domain TK2160 86fc844362bccfe54cd1e7ddade494ab 443 Pfam PF13353 4Fe-4S single cluster domain 101 222 1.4E-14 T 31-10-2018 TK2160 86fc844362bccfe54cd1e7ddade494ab 443 Gene3D G3DSA:3.20.20.70 93 438 4.7E-47 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TK2160 86fc844362bccfe54cd1e7ddade494ab 443 Pfam PF04055 Radical SAM superfamily 99 238 6.9E-11 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TK2160 86fc844362bccfe54cd1e7ddade494ab 443 SUPERFAMILY SSF102114 97 402 4.71E-39 T 31-10-2018 TK2160 86fc844362bccfe54cd1e7ddade494ab 443 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 101 112 - T 31-10-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TK0872 2dfed3d4570c1af7be9afdbf8a48c7f5 309 ProSitePatterns PS01153 NOL1/NOP2/sun family signature. 182 193 - T 31-10-2018 IPR018314 Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site GO:0003723|GO:0008168 TK0872 2dfed3d4570c1af7be9afdbf8a48c7f5 309 Pfam PF17125 N-terminal domain of 16S rRNA methyltransferase RsmF 12 102 1.0E-20 T 31-10-2018 IPR031341 Ribosomal RNA small subunit methyltransferase F, N-terminal Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 TK0872 2dfed3d4570c1af7be9afdbf8a48c7f5 309 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 233 249 8.6E-30 T 31-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TK0872 2dfed3d4570c1af7be9afdbf8a48c7f5 309 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 117 127 8.6E-30 T 31-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TK0872 2dfed3d4570c1af7be9afdbf8a48c7f5 309 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 183 195 8.6E-30 T 31-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TK0872 2dfed3d4570c1af7be9afdbf8a48c7f5 309 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 291 308 8.6E-30 T 31-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TK0872 2dfed3d4570c1af7be9afdbf8a48c7f5 309 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 88 102 8.6E-30 T 31-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TK0872 2dfed3d4570c1af7be9afdbf8a48c7f5 309 Gene3D G3DSA:3.30.70.3130 1 101 3.4E-36 T 31-10-2018 TK0872 2dfed3d4570c1af7be9afdbf8a48c7f5 309 Pfam PF01189 16S rRNA methyltransferase RsmB/F 106 307 4.8E-57 T 31-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 TK0872 2dfed3d4570c1af7be9afdbf8a48c7f5 309 Gene3D G3DSA:3.40.50.150 103 309 2.3E-68 T 31-10-2018 TK0872 2dfed3d4570c1af7be9afdbf8a48c7f5 309 TIGRFAM TIGR00446 nop2p: NOL1/NOP2/sun family putative RNA methylase 42 308 5.4E-89 T 31-10-2018 IPR011023 Nop2p GO:0003723|GO:0006364|GO:0008757 Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 TK0872 2dfed3d4570c1af7be9afdbf8a48c7f5 309 SUPERFAMILY SSF53335 7 308 4.18E-76 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TK1061 14df9cfe22e02b29468d4e48ca356559 102 SUPERFAMILY SSF47240 42 100 8.97E-9 T 31-10-2018 IPR009078 Ferritin-like superfamily TK1061 14df9cfe22e02b29468d4e48ca356559 102 Gene3D G3DSA:1.20.1260.10 10 99 6.7E-7 T 31-10-2018 IPR012347 Ferritin-like TK0927 77d510d7844b6ad227bfb9b4171e530c 267 SUPERFAMILY SSF55120 1 230 4.17E-66 T 31-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 TK0927 77d510d7844b6ad227bfb9b4171e530c 267 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 2 222 1.2E-54 T 31-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 TK0927 77d510d7844b6ad227bfb9b4171e530c 267 PIRSF PIRSF001430 1 243 1.1E-79 T 31-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 TK0927 77d510d7844b6ad227bfb9b4171e530c 267 Gene3D G3DSA:3.30.70.660 104 226 1.9E-28 T 31-10-2018 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0003723|GO:0009982 TK0927 77d510d7844b6ad227bfb9b4171e530c 267 Pfam PF01416 tRNA pseudouridine synthase 129 228 1.8E-23 T 31-10-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 TK0927 77d510d7844b6ad227bfb9b4171e530c 267 Gene3D G3DSA:3.30.70.580 1 103 4.4E-23 T 31-10-2018 TK0927 77d510d7844b6ad227bfb9b4171e530c 267 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 1 227 31.353 T 31-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 TK1429 82a0591d0574da38f47d3a2c3d572384 203 TIGRFAM TIGR03634 arc_protsome_B: proteasome endopeptidase complex, archaeal, beta subunit 7 190 3.9E-78 T 31-10-2018 IPR019983 Peptidase T1A, proteasome beta-subunit, archaeal GO:0004175|GO:0005839|GO:0051603 TK1429 82a0591d0574da38f47d3a2c3d572384 203 ProSitePatterns PS00854 Proteasome beta-type subunits signature. 11 58 - T 31-10-2018 IPR016050 Proteasome beta-type subunit, conserved site GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 TK1429 82a0591d0574da38f47d3a2c3d572384 203 Hamap MF_02113_A Proteasome subunit beta [prcB]. 3 197 36.107 T 31-10-2018 IPR019983 Peptidase T1A, proteasome beta-subunit, archaeal GO:0004175|GO:0005839|GO:0051603 TK1429 82a0591d0574da38f47d3a2c3d572384 203 SUPERFAMILY SSF56235 5 202 4.07E-63 T 31-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TK1429 82a0591d0574da38f47d3a2c3d572384 203 Gene3D G3DSA:3.60.20.10 3 203 2.9E-67 T 31-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TK1429 82a0591d0574da38f47d3a2c3d572384 203 Pfam PF00227 Proteasome subunit 6 185 2.1E-53 T 31-10-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 TK1429 82a0591d0574da38f47d3a2c3d572384 203 PRINTS PR00141 Proteasome component signature 15 30 8.8E-11 T 31-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 TK1429 82a0591d0574da38f47d3a2c3d572384 203 PRINTS PR00141 Proteasome component signature 146 157 8.8E-11 T 31-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 TK1429 82a0591d0574da38f47d3a2c3d572384 203 PRINTS PR00141 Proteasome component signature 135 146 8.8E-11 T 31-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 TK1429 82a0591d0574da38f47d3a2c3d572384 203 PRINTS PR00141 Proteasome component signature 171 182 8.8E-11 T 31-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 TK0653 3779a4b2352c427d9b83e4ab8cd64400 342 Pfam PF00448 SRP54-type protein, GTPase domain 145 339 1.3E-80 T 31-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 TK0653 3779a4b2352c427d9b83e4ab8cd64400 342 SUPERFAMILY SSF52540 143 340 2.83E-56 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK0653 3779a4b2352c427d9b83e4ab8cd64400 342 SMART SM00963 41 126 6.6E-11 T 31-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 TK0653 3779a4b2352c427d9b83e4ab8cd64400 342 SMART SM00382 144 339 5.8E-9 T 31-10-2018 IPR003593 AAA+ ATPase domain TK0653 3779a4b2352c427d9b83e4ab8cd64400 342 Gene3D G3DSA:1.20.120.140 31 128 8.6E-25 T 31-10-2018 TK0653 3779a4b2352c427d9b83e4ab8cd64400 342 SMART SM00962 145 340 1.2E-115 T 31-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 TK0653 3779a4b2352c427d9b83e4ab8cd64400 342 SUPERFAMILY SSF47364 60 130 1.44E-16 T 31-10-2018 IPR036225 SRP/SRP receptor, N-terminal Reactome: R-HSA-1799339 TK0653 3779a4b2352c427d9b83e4ab8cd64400 342 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 65 340 59.284 T 31-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 TK0653 3779a4b2352c427d9b83e4ab8cd64400 342 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 313 326 - T 31-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 TK0653 3779a4b2352c427d9b83e4ab8cd64400 342 Gene3D G3DSA:3.40.50.300 131 339 2.0E-86 T 31-10-2018 TK0653 3779a4b2352c427d9b83e4ab8cd64400 342 Pfam PF02881 SRP54-type protein, helical bundle domain 61 121 2.0E-12 T 31-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 TK0653 3779a4b2352c427d9b83e4ab8cd64400 342 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 66 339 1.1E-109 T 31-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 TK1088 9c73dcf926595181c375aab32e0e8f53 395 Gene3D G3DSA:3.30.9.10 71 358 3.4E-106 T 31-10-2018 TK1088 9c73dcf926595181c375aab32e0e8f53 395 Pfam PF05834 Lycopene cyclase protein 6 329 4.9E-13 T 31-10-2018 TK1088 9c73dcf926595181c375aab32e0e8f53 395 TIGRFAM TIGR02032 GG-red-SF: geranylgeranyl reductase family 5 303 2.3E-74 T 31-10-2018 IPR011777 Geranylgeranyl reductase family GO:0016628|GO:0055114 TK1088 9c73dcf926595181c375aab32e0e8f53 395 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 268 283 8.0E-10 T 31-10-2018 TK1088 9c73dcf926595181c375aab32e0e8f53 395 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 146 161 8.0E-10 T 31-10-2018 TK1088 9c73dcf926595181c375aab32e0e8f53 395 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 8.0E-10 T 31-10-2018 TK1088 9c73dcf926595181c375aab32e0e8f53 395 SUPERFAMILY SSF51905 3 340 7.08E-38 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TK1088 9c73dcf926595181c375aab32e0e8f53 395 Gene3D G3DSA:3.50.50.60 5 340 3.4E-106 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TK1088 9c73dcf926595181c375aab32e0e8f53 395 Hamap MF_01287 Digeranylgeranylglycerophospholipid reductase. 3 389 38.88 T 31-10-2018 IPR023590 Digeranylgeranylglycerophospholipid reductase GO:0016628|GO:0045550|GO:0046467|GO:0055114 KEGG: 00564+1.3.7.11|MetaCyc: PWY-6349 TK0306 ab24e8162c3bdcf76a9b54aca0bc4c97 406 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 149 157 - T 31-10-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site TK0306 ab24e8162c3bdcf76a9b54aca0bc4c97 406 SUPERFAMILY SSF52540 70 357 5.1E-77 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK0306 ab24e8162c3bdcf76a9b54aca0bc4c97 406 Pfam PF00270 DEAD/DEAH box helicase 25 189 4.6E-49 T 31-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 TK0306 ab24e8162c3bdcf76a9b54aca0bc4c97 406 Gene3D G3DSA:3.40.50.300 1 207 4.2E-76 T 31-10-2018 TK0306 ab24e8162c3bdcf76a9b54aca0bc4c97 406 Pfam PF00271 Helicase conserved C-terminal domain 229 336 2.4E-30 T 31-10-2018 IPR001650 Helicase, C-terminal TK0306 ab24e8162c3bdcf76a9b54aca0bc4c97 406 Gene3D G3DSA:3.40.50.300 214 402 2.0E-53 T 31-10-2018 TK0306 ab24e8162c3bdcf76a9b54aca0bc4c97 406 SMART SM00490 255 336 1.9E-35 T 31-10-2018 IPR001650 Helicase, C-terminal TK0306 ab24e8162c3bdcf76a9b54aca0bc4c97 406 SMART SM00487 20 218 1.5E-63 T 31-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TK0843 a64bee552f56224ec9a045eb48d87dc3 154 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 6 127 5.3E-25 T 31-10-2018 IPR023485 Phosphotyrosine protein phosphatase I TK0843 a64bee552f56224ec9a045eb48d87dc3 154 SMART SM00226 4 130 2.4E-43 T 31-10-2018 IPR023485 Phosphotyrosine protein phosphatase I TK0843 a64bee552f56224ec9a045eb48d87dc3 154 Gene3D G3DSA:3.40.50.2300 4 136 1.7E-45 T 31-10-2018 TK0843 a64bee552f56224ec9a045eb48d87dc3 154 SUPERFAMILY SSF52788 6 129 2.49E-36 T 31-10-2018 IPR036196 Phosphotyrosine protein phosphatase I superfamily TK0893 0e095b139f3475d40ca1b21cbf34f786 349 Pfam PF04055 Radical SAM superfamily 78 234 2.1E-22 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TK0893 0e095b139f3475d40ca1b21cbf34f786 349 PIRSF PIRSF004869 1 313 1.7E-97 T 31-10-2018 IPR016431 Pyruvate-formate lyase-activating enzyme, predicted TK0893 0e095b139f3475d40ca1b21cbf34f786 349 SUPERFAMILY SSF102114 52 317 2.49E-37 T 31-10-2018 TK0893 0e095b139f3475d40ca1b21cbf34f786 349 TIGRFAM TIGR04337 AmmeMemoSam_rS: AmmeMemoRadiSam system radical SAM enzyme 5 342 4.4E-111 T 31-10-2018 IPR027596 AmmeMemoRadiSam system radical SAM enzyme TK0893 0e095b139f3475d40ca1b21cbf34f786 349 Pfam PF13353 4Fe-4S single cluster domain 73 166 2.3E-7 T 31-10-2018 TK0893 0e095b139f3475d40ca1b21cbf34f786 349 Gene3D G3DSA:3.20.20.70 63 286 9.6E-37 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TK0289 4ffefc0370bf921ff9f3e80c79f3dd64 819 Pfam PF02901 Pyruvate formate lyase-like 32 681 3.7E-222 T 31-10-2018 IPR004184 Pyruvate formate lyase domain GO:0003824 TK0289 4ffefc0370bf921ff9f3e80c79f3dd64 819 Gene3D G3DSA:3.20.70.40 30 818 7.9E-283 T 31-10-2018 TK0289 4ffefc0370bf921ff9f3e80c79f3dd64 819 SUPERFAMILY SSF51998 27 817 1.68E-230 T 31-10-2018 TK0289 4ffefc0370bf921ff9f3e80c79f3dd64 819 Pfam PF01228 Glycine radical 697 800 4.1E-29 T 31-10-2018 IPR001150 Glycine radical domain GO:0003824 TK1213 5a5d0dedd7eac5375c84e2d89aada10d 207 Pfam PF06195 Protein of unknown function (DUF996) 41 178 1.4E-29 T 31-10-2018 IPR010397 Protein of unknown function DUF996 TK1322 613ee709a2f7f903547693ffbfa7c990 77 ProDom PD010302 RIBOSOMAL LX 50S RIBONUCLEOPROTEIN HL32 DIRECT SEQUENCING LXA LSU 6 51 4.0E-20 T 31-10-2018 IPR002768 50S ribosomal protein L18Ae, archaea GO:0003735|GO:0005840|GO:0006412 TK1322 613ee709a2f7f903547693ffbfa7c990 77 SUPERFAMILY SSF160374 1 73 1.57E-25 T 31-10-2018 TK1322 613ee709a2f7f903547693ffbfa7c990 77 Gene3D G3DSA:3.10.20.10 3 76 1.3E-29 T 31-10-2018 TK1322 613ee709a2f7f903547693ffbfa7c990 77 Hamap MF_00273 50S ribosomal protein L18Ae [rpl18a]. 3 58 21.178 T 31-10-2018 IPR028877 50S ribosomal protein L18Ae/60S ribosomal protein L20 and L18a Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1322 613ee709a2f7f903547693ffbfa7c990 77 Pfam PF01775 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A 2 58 2.9E-12 T 31-10-2018 IPR023573 Ribosomal protein 50S-L18Ae/60S-L20/60S-L18A GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1146 e46fa6268757063e79f963e39fddcb92 411 Gene3D G3DSA:3.40.50.1260 189 390 9.4E-137 T 31-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TK1146 e46fa6268757063e79f963e39fddcb92 411 PIRSF PIRSF000724 1 407 1.1E-129 T 31-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TK1146 e46fa6268757063e79f963e39fddcb92 411 ProSitePatterns PS00111 Phosphoglycerate kinase signature. 13 23 - T 31-10-2018 IPR015911 Phosphoglycerate kinase, conserved site GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TK1146 e46fa6268757063e79f963e39fddcb92 411 SUPERFAMILY SSF53748 2 399 2.24E-116 T 31-10-2018 IPR036043 Phosphoglycerate kinase superfamily GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TK1146 e46fa6268757063e79f963e39fddcb92 411 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 4 400 34.77 T 31-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TK1146 e46fa6268757063e79f963e39fddcb92 411 PRINTS PR00477 Phosphoglycerate kinase family signature 8 24 5.1E-68 T 31-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TK1146 e46fa6268757063e79f963e39fddcb92 411 PRINTS PR00477 Phosphoglycerate kinase family signature 354 365 5.1E-68 T 31-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TK1146 e46fa6268757063e79f963e39fddcb92 411 PRINTS PR00477 Phosphoglycerate kinase family signature 170 192 5.1E-68 T 31-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TK1146 e46fa6268757063e79f963e39fddcb92 411 PRINTS PR00477 Phosphoglycerate kinase family signature 29 51 5.1E-68 T 31-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TK1146 e46fa6268757063e79f963e39fddcb92 411 PRINTS PR00477 Phosphoglycerate kinase family signature 140 162 5.1E-68 T 31-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TK1146 e46fa6268757063e79f963e39fddcb92 411 PRINTS PR00477 Phosphoglycerate kinase family signature 321 346 5.1E-68 T 31-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TK1146 e46fa6268757063e79f963e39fddcb92 411 PRINTS PR00477 Phosphoglycerate kinase family signature 105 120 5.1E-68 T 31-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TK1146 e46fa6268757063e79f963e39fddcb92 411 PRINTS PR00477 Phosphoglycerate kinase family signature 193 212 5.1E-68 T 31-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TK1146 e46fa6268757063e79f963e39fddcb92 411 PRINTS PR00477 Phosphoglycerate kinase family signature 376 393 5.1E-68 T 31-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TK1146 e46fa6268757063e79f963e39fddcb92 411 Pfam PF00162 Phosphoglycerate kinase 4 389 3.1E-106 T 31-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TK1146 e46fa6268757063e79f963e39fddcb92 411 Gene3D G3DSA:3.40.50.1260 10 397 9.4E-137 T 31-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TK1292 701be6e0b7557bcc97fd6c5b569c1922 793 PIRSF PIRSF000854 1 542 1.1E-148 T 31-10-2018 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484|MetaCyc: PWY-6142 TK1292 701be6e0b7557bcc97fd6c5b569c1922 793 PIRSF PIRSF000854 533 777 3.2E-59 T 31-10-2018 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484|MetaCyc: PWY-6142 TK1292 701be6e0b7557bcc97fd6c5b569c1922 793 Gene3D G3DSA:3.30.1490.20 3 197 1.6E-72 T 31-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 TK1292 701be6e0b7557bcc97fd6c5b569c1922 793 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 486 772 2.5E-98 T 31-10-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 TK1292 701be6e0b7557bcc97fd6c5b569c1922 793 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 19 350 3.3E-119 T 31-10-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 TK1292 701be6e0b7557bcc97fd6c5b569c1922 793 SUPERFAMILY SSF51621 487 780 9.68E-96 T 31-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 TK1292 701be6e0b7557bcc97fd6c5b569c1922 793 Gene3D G3DSA:3.30.470.20 198 353 1.8E-54 T 31-10-2018 TK1292 701be6e0b7557bcc97fd6c5b569c1922 793 Gene3D G3DSA:3.20.20.60 462 791 1.7E-105 T 31-10-2018 TK1292 701be6e0b7557bcc97fd6c5b569c1922 793 Gene3D G3DSA:3.50.30.10 354 461 3.7E-43 T 31-10-2018 TK1292 701be6e0b7557bcc97fd6c5b569c1922 793 SUPERFAMILY SSF52009 353 461 3.92E-37 T 31-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 TK1292 701be6e0b7557bcc97fd6c5b569c1922 793 Pfam PF00391 PEP-utilising enzyme, mobile domain 381 453 8.1E-29 T 31-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 TK1292 701be6e0b7557bcc97fd6c5b569c1922 793 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 695 710 8.0E-14 T 31-10-2018 TK1292 701be6e0b7557bcc97fd6c5b569c1922 793 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 514 533 8.0E-14 T 31-10-2018 TK1292 701be6e0b7557bcc97fd6c5b569c1922 793 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 678 693 8.0E-14 T 31-10-2018 TK1292 701be6e0b7557bcc97fd6c5b569c1922 793 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 731 743 8.0E-14 T 31-10-2018 TK1292 701be6e0b7557bcc97fd6c5b569c1922 793 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 678 696 - T 31-10-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 TK1292 701be6e0b7557bcc97fd6c5b569c1922 793 SUPERFAMILY SSF56059 4 381 4.71E-107 T 31-10-2018 TK1292 701be6e0b7557bcc97fd6c5b569c1922 793 TIGRFAM TIGR01418 PEP_synth: phosphoenolpyruvate synthase 7 773 3.1E-290 T 31-10-2018 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484|MetaCyc: PWY-6142 TK1292 701be6e0b7557bcc97fd6c5b569c1922 793 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 412 423 - T 31-10-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 TK1624 154dfffda69de4351979549087afa8f6 157 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 113 130 - T 31-10-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 TK1624 154dfffda69de4351979549087afa8f6 157 Gene3D G3DSA:2.40.50.100 84 157 1.8E-30 T 31-10-2018 TK1624 154dfffda69de4351979549087afa8f6 157 Pfam PF00364 Biotin-requiring enzyme 91 156 3.3E-25 T 31-10-2018 IPR000089 Biotin/lipoyl attachment TK1624 154dfffda69de4351979549087afa8f6 157 SUPERFAMILY SSF51230 81 156 4.97E-27 T 31-10-2018 IPR011053 Single hybrid motif TK1273 bda7ce2a83171bfd68c0ecf598bed06c 249 Pfam PF13649 Methyltransferase domain 45 139 2.5E-25 T 31-10-2018 TK1273 bda7ce2a83171bfd68c0ecf598bed06c 249 Gene3D G3DSA:3.40.50.150 1 148 1.6E-50 T 31-10-2018 TK1273 bda7ce2a83171bfd68c0ecf598bed06c 249 Gene3D G3DSA:2.20.25.110 149 209 8.9E-37 T 31-10-2018 TK1273 bda7ce2a83171bfd68c0ecf598bed06c 249 SUPERFAMILY SSF53335 1 244 2.69E-47 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TK1884 9cdee35e35b55112bdc16f8f2341cd0b 461 SMART SM00642 36 381 1.5E-28 T 31-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 TK1884 9cdee35e35b55112bdc16f8f2341cd0b 461 SUPERFAMILY SSF51445 33 385 8.8E-70 T 31-10-2018 IPR017853 Glycoside hydrolase superfamily TK1884 9cdee35e35b55112bdc16f8f2341cd0b 461 Pfam PF00128 Alpha amylase, catalytic domain 56 339 1.0E-11 T 31-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 TK1884 9cdee35e35b55112bdc16f8f2341cd0b 461 PIRSF PIRSF001021 2 461 1.9E-119 T 31-10-2018 IPR013776 Alpha-amylase, thermostable GO:0004553|GO:0005509|GO:0005975 KEGG: 00500+3.2.1.1 TK1884 9cdee35e35b55112bdc16f8f2341cd0b 461 Pfam PF09154 Domain of unknown function (DUF1939) 390 456 5.1E-21 T 31-10-2018 IPR015237 Alpha-amylase C-terminal, prokaryotic GO:0004553 TK1884 9cdee35e35b55112bdc16f8f2341cd0b 461 Gene3D G3DSA:2.60.40.1180 364 461 1.3E-48 T 31-10-2018 IPR013780 Glycosyl hydrolase, all-beta TK1884 9cdee35e35b55112bdc16f8f2341cd0b 461 SUPERFAMILY SSF51011 388 461 5.83E-37 T 31-10-2018 TK1884 9cdee35e35b55112bdc16f8f2341cd0b 461 PRINTS PR00110 Alpha-amylase signature 305 317 3.3E-5 T 31-10-2018 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 TK1884 9cdee35e35b55112bdc16f8f2341cd0b 461 PRINTS PR00110 Alpha-amylase signature 218 229 3.3E-5 T 31-10-2018 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 TK1884 9cdee35e35b55112bdc16f8f2341cd0b 461 PRINTS PR00110 Alpha-amylase signature 126 137 3.3E-5 T 31-10-2018 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 TK1884 9cdee35e35b55112bdc16f8f2341cd0b 461 Gene3D G3DSA:3.20.20.80 27 363 2.0E-107 T 31-10-2018 TK1406 2d801423d217f402dccf55ab922ea7fc 830 PIRSF PIRSF000460 1 768 2.0E-275 T 31-10-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 TK1406 2d801423d217f402dccf55ab922ea7fc 830 Gene3D G3DSA:3.40.50.2000 117 185 2.3E-11 T 31-10-2018 TK1406 2d801423d217f402dccf55ab922ea7fc 830 Gene3D G3DSA:3.40.50.2000 407 727 5.9E-44 T 31-10-2018 TK1406 2d801423d217f402dccf55ab922ea7fc 830 TIGRFAM TIGR02094 more_P_ylases: alpha-glucan phosphorylases 110 692 5.5E-256 T 31-10-2018 IPR011834 Alpha-glucan phosphorylase GO:0004645|GO:0005975|GO:0030170 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238 TK1406 2d801423d217f402dccf55ab922ea7fc 830 ProSitePatterns PS00102 Phosphorylase pyridoxal-phosphate attachment site. 586 598 - T 31-10-2018 IPR035090 Phosphorylase pyridoxal-phosphate attachment site KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 TK1406 2d801423d217f402dccf55ab922ea7fc 830 Pfam PF11897 Protein of unknown function (DUF3417) 16 123 3.3E-31 T 31-10-2018 IPR024517 Glycogen phosphorylase, domain of unknown function DUF3417 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238 TK1406 2d801423d217f402dccf55ab922ea7fc 830 Pfam PF00343 Carbohydrate phosphorylase 127 176 2.2E-5 T 31-10-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 TK1406 2d801423d217f402dccf55ab922ea7fc 830 Pfam PF00343 Carbohydrate phosphorylase 273 612 3.6E-26 T 31-10-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 TK1406 2d801423d217f402dccf55ab922ea7fc 830 Gene3D G3DSA:3.40.50.2000 269 406 3.3E-8 T 31-10-2018 TK1406 2d801423d217f402dccf55ab922ea7fc 830 SUPERFAMILY SSF53756 17 726 1.61E-206 T 31-10-2018 TK0307 1fb5872958208192940131d7ef3bd727 102 Pfam PF00338 Ribosomal protein S10p/S20e 5 98 1.2E-27 T 31-10-2018 IPR027486 Ribosomal protein S10 domain TK0307 1fb5872958208192940131d7ef3bd727 102 SMART SM01403 5 99 1.5E-41 T 31-10-2018 IPR027486 Ribosomal protein S10 domain TK0307 1fb5872958208192940131d7ef3bd727 102 SUPERFAMILY SSF54999 3 100 3.92E-29 T 31-10-2018 IPR036838 Ribosomal protein S10 domain superfamily TK0307 1fb5872958208192940131d7ef3bd727 102 Gene3D G3DSA:3.30.70.600 1 101 4.6E-35 T 31-10-2018 IPR036838 Ribosomal protein S10 domain superfamily TK0307 1fb5872958208192940131d7ef3bd727 102 ProSitePatterns PS00361 Ribosomal protein S10 signature. 27 42 - T 31-10-2018 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK0307 1fb5872958208192940131d7ef3bd727 102 PRINTS PR00971 Ribosomal protein S10 family signature 3 16 1.6E-16 T 31-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK0307 1fb5872958208192940131d7ef3bd727 102 PRINTS PR00971 Ribosomal protein S10 family signature 60 74 1.6E-16 T 31-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK0307 1fb5872958208192940131d7ef3bd727 102 PRINTS PR00971 Ribosomal protein S10 family signature 38 53 1.6E-16 T 31-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK0307 1fb5872958208192940131d7ef3bd727 102 TIGRFAM TIGR01046 uS10_euk_arch: ribosomal protein uS10 2 100 1.0E-50 T 31-10-2018 IPR005729 Ribosomal protein S10, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK0307 1fb5872958208192940131d7ef3bd727 102 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 1 100 24.692 T 31-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1756 ef14599811b55ea2f01e5b70084915db 322 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 233 298 2.5E-20 T 31-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TK1756 ef14599811b55ea2f01e5b70084915db 322 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 232 318 1.7E-21 T 31-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TK1756 ef14599811b55ea2f01e5b70084915db 322 SUPERFAMILY SSF52540 5 253 5.92E-63 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK1756 ef14599811b55ea2f01e5b70084915db 322 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TK1756 ef14599811b55ea2f01e5b70084915db 322 Pfam PF00005 ABC transporter 29 181 6.2E-30 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TK1756 ef14599811b55ea2f01e5b70084915db 322 Gene3D G3DSA:3.40.50.300 4 321 7.4E-88 T 31-10-2018 TK1756 ef14599811b55ea2f01e5b70084915db 322 SMART SM00382 37 231 2.6E-16 T 31-10-2018 IPR003593 AAA+ ATPase domain TK1188 840b85105f56469f6dce8c76f1f7940a 419 SUPERFAMILY SSF51161 243 409 5.89E-40 T 31-10-2018 IPR011004 Trimeric LpxA-like superfamily TK1188 840b85105f56469f6dce8c76f1f7940a 419 Gene3D G3DSA:3.90.550.10 1 224 1.9E-53 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TK1188 840b85105f56469f6dce8c76f1f7940a 419 TIGRFAM TIGR03992 Arch_glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 1 398 3.8E-155 T 31-10-2018 IPR023915 UDP-GlcNAc diphosphorylase/GlcNAc-1-P N-acetyltransferase, GlmU, archaeal-type GO:0003977|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|MetaCyc: PWY-5514 TK1188 840b85105f56469f6dce8c76f1f7940a 419 SUPERFAMILY SSF53448 1 312 3.29E-71 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TK1188 840b85105f56469f6dce8c76f1f7940a 419 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 254 287 8.9E-10 T 31-10-2018 IPR001451 Hexapeptide repeat TK1188 840b85105f56469f6dce8c76f1f7940a 419 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 365 399 1.2E-5 T 31-10-2018 IPR001451 Hexapeptide repeat TK1188 840b85105f56469f6dce8c76f1f7940a 419 Gene3D G3DSA:2.160.10.10 225 410 7.6E-61 T 31-10-2018 TK1188 840b85105f56469f6dce8c76f1f7940a 419 Pfam PF00483 Nucleotidyl transferase 2 232 2.9E-39 T 31-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 TK0974 ed9e8742e702d593a17103b65a32bd16 455 TIGRFAM TIGR00797 matE: MATE efflux family protein 16 427 6.1E-127 T 31-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 TK0974 ed9e8742e702d593a17103b65a32bd16 455 Pfam PF01554 MatE 16 176 7.7E-38 T 31-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 TK0974 ed9e8742e702d593a17103b65a32bd16 455 Pfam PF01554 MatE 240 406 6.8E-38 T 31-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 TK0974 ed9e8742e702d593a17103b65a32bd16 455 PIRSF PIRSF006603 1 455 6.5E-108 T 31-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 TK1470 3c6b2dbd967c5e85c5b6cb07cbe8c094 374 Hamap MF_00354 Isopentenyl-diphosphate delta-isomerase [fni]. 10 353 41.059 T 31-10-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 TK1470 3c6b2dbd967c5e85c5b6cb07cbe8c094 374 PIRSF PIRSF003314 7 363 5.6E-133 T 31-10-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 TK1470 3c6b2dbd967c5e85c5b6cb07cbe8c094 374 TIGRFAM TIGR02151 IPP_isom_2: isopentenyl-diphosphate delta-isomerase, type 2 13 352 6.2E-131 T 31-10-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 TK1470 3c6b2dbd967c5e85c5b6cb07cbe8c094 374 Gene3D G3DSA:3.20.20.70 10 373 1.2E-128 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TK1470 3c6b2dbd967c5e85c5b6cb07cbe8c094 374 SMART SM01240 30 349 0.0019 T 31-10-2018 TK1470 3c6b2dbd967c5e85c5b6cb07cbe8c094 374 Pfam PF01070 FMN-dependent dehydrogenase 14 105 1.1E-8 T 31-10-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 Reactome: R-HSA-9033241 TK1470 3c6b2dbd967c5e85c5b6cb07cbe8c094 374 Pfam PF01070 FMN-dependent dehydrogenase 186 346 6.3E-16 T 31-10-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 Reactome: R-HSA-9033241 TK1470 3c6b2dbd967c5e85c5b6cb07cbe8c094 374 SUPERFAMILY SSF51395 32 369 1.2E-80 T 31-10-2018 TK0281 0b8f0b08c7f82088a927800f474af138 163 Gene3D G3DSA:3.20.19.10 1 156 1.8E-52 T 31-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 TK0281 0b8f0b08c7f82088a927800f474af138 163 SUPERFAMILY SSF52016 3 158 2.16E-45 T 31-10-2018 TK0281 0b8f0b08c7f82088a927800f474af138 163 Pfam PF00694 Aconitase C-terminal domain 21 100 2.3E-18 T 31-10-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 TK0281 0b8f0b08c7f82088a927800f474af138 163 TIGRFAM TIGR02087 LEUD_arch: 3-isopropylmalate dehydratase, small subunit 5 156 7.4E-64 T 31-10-2018 IPR011827 Hydrolyase LeuD/HacB/DmdB GO:0016836 KEGG: 00290+4.2.1.33 TK0281 0b8f0b08c7f82088a927800f474af138 163 Hamap MF_01032 Methanogen homoaconitase small subunit [hacB]. 3 159 35.449 T 31-10-2018 IPR011827 Hydrolyase LeuD/HacB/DmdB GO:0016836 KEGG: 00290+4.2.1.33 TK1929 e4744bd0ad0bc35aef667703a3413555 592 SUPERFAMILY SSF48371 26 586 1.81E-24 T 31-10-2018 IPR016024 Armadillo-type fold TK1929 e4744bd0ad0bc35aef667703a3413555 592 Gene3D G3DSA:1.25.10.10 371 591 2.4E-9 T 31-10-2018 IPR011989 Armadillo-like helical TK1929 e4744bd0ad0bc35aef667703a3413555 592 Gene3D G3DSA:1.25.10.10 2 261 8.0E-65 T 31-10-2018 IPR011989 Armadillo-like helical TK0749 38f9b94bacb3b3584fabd3e9bfb47a5d 195 SUPERFAMILY SSF53448 1 124 7.51E-7 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TK0749 38f9b94bacb3b3584fabd3e9bfb47a5d 195 Gene3D G3DSA:3.90.550.10 17 191 8.6E-10 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TK1786 4df3dfcbea608f193c934853e49e0e4c 102 Gene3D G3DSA:3.30.720.70 1 102 1.9E-50 T 31-10-2018 TK0836 c15eb6496c35250319d173250fc717c3 174 SMART SM01001 2 151 4.1E-110 T 31-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 TK0836 c15eb6496c35250319d173250fc717c3 174 Gene3D G3DSA:3.40.50.7700 1 170 1.6E-85 T 31-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 TK0836 c15eb6496c35250319d173250fc717c3 174 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 4 158 1.0E-72 T 31-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 TK0836 c15eb6496c35250319d173250fc717c3 174 PIRSF PIRSF001338 1 162 1.1E-77 T 31-10-2018 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 TK0836 c15eb6496c35250319d173250fc717c3 174 SUPERFAMILY SSF52255 2 167 1.7E-72 T 31-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 TK0836 c15eb6496c35250319d173250fc717c3 174 Pfam PF00731 AIR carboxylase 3 149 7.5E-73 T 31-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 TK0836 c15eb6496c35250319d173250fc717c3 174 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 4 155 35.414 T 31-10-2018 IPR033747 Class I PurE TK1938 f87854abef4237c5232b52cc0b6d6173 232 Pfam PF12679 ABC-2 family transporter protein 71 197 4.9E-8 T 31-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 TK0464 546ec8089dda2f8494e582e060d93881 263 Gene3D G3DSA:3.30.70.1900 124 242 2.2E-37 T 31-10-2018 TK0464 546ec8089dda2f8494e582e060d93881 263 TIGRFAM TIGR01877 cas_cas6: CRISPR-associated endoribonuclease Cas6 44 239 2.6E-47 T 31-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 TK0464 546ec8089dda2f8494e582e060d93881 263 Gene3D G3DSA:3.30.70.1890 1 123 6.0E-38 T 31-10-2018 TK0464 546ec8089dda2f8494e582e060d93881 263 Pfam PF01881 CRISPR associated protein Cas6 96 240 5.9E-34 T 31-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 TK0464 546ec8089dda2f8494e582e060d93881 263 PIRSF PIRSF005054 2 244 3.1E-67 T 31-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 TK0528 0d6e2e538ab3c9231c4a9a35f3ad89d5 431 Pfam PF00464 Serine hydroxymethyltransferase 11 390 4.0E-81 T 31-10-2018 IPR039429 Serine hydroxymethyltransferase-like domain KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 TK0528 0d6e2e538ab3c9231c4a9a35f3ad89d5 431 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 5 418 43.66 T 31-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 TK0528 0d6e2e538ab3c9231c4a9a35f3ad89d5 431 PIRSF PIRSF000412 3 424 5.8E-145 T 31-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 TK0528 0d6e2e538ab3c9231c4a9a35f3ad89d5 431 SUPERFAMILY SSF53383 5 423 8.07E-133 T 31-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TK0528 0d6e2e538ab3c9231c4a9a35f3ad89d5 431 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 220 236 - T 31-10-2018 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 TK0528 0d6e2e538ab3c9231c4a9a35f3ad89d5 431 Gene3D G3DSA:3.40.640.10 38 280 1.4E-84 T 31-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TK0528 0d6e2e538ab3c9231c4a9a35f3ad89d5 431 Gene3D G3DSA:3.90.1150.10 281 428 6.2E-53 T 31-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TK1840 015f98fbcaf49a67ba257293dee19c73 499 PIRSF PIRSF006615 5 499 1.1E-198 T 31-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 TK1840 015f98fbcaf49a67ba257293dee19c73 499 Pfam PF02074 Carboxypeptidase Taq (M32) metallopeptidase 12 498 7.6E-108 T 31-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 TK1840 015f98fbcaf49a67ba257293dee19c73 499 SUPERFAMILY SSF55486 7 499 1.83E-116 T 31-10-2018 TK1840 015f98fbcaf49a67ba257293dee19c73 499 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 296 312 8.0E-87 T 31-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 TK1840 015f98fbcaf49a67ba257293dee19c73 499 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 269 288 8.0E-87 T 31-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 TK1840 015f98fbcaf49a67ba257293dee19c73 499 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 336 355 8.0E-87 T 31-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 TK1840 015f98fbcaf49a67ba257293dee19c73 499 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 405 426 8.0E-87 T 31-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 TK1840 015f98fbcaf49a67ba257293dee19c73 499 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 249 268 8.0E-87 T 31-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 TK1840 015f98fbcaf49a67ba257293dee19c73 499 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 150 170 8.0E-87 T 31-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 TK1840 015f98fbcaf49a67ba257293dee19c73 499 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 232 248 8.0E-87 T 31-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 TK1840 015f98fbcaf49a67ba257293dee19c73 499 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 382 399 8.0E-87 T 31-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 TK1840 015f98fbcaf49a67ba257293dee19c73 499 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 450 468 8.0E-87 T 31-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 TK1840 015f98fbcaf49a67ba257293dee19c73 499 Gene3D G3DSA:1.10.1370.30 1 499 2.1E-199 T 31-10-2018 TK1036 7c2be6ed951b5376829b65428a617202 136 SUPERFAMILY SSF54631 9 128 2.15E-33 T 31-10-2018 TK1036 7c2be6ed951b5376829b65428a617202 136 SMART SM00116 14 62 1.9E-8 T 31-10-2018 IPR000644 CBS domain TK1036 7c2be6ed951b5376829b65428a617202 136 SMART SM00116 79 126 1.4E-8 T 31-10-2018 IPR000644 CBS domain TK1036 7c2be6ed951b5376829b65428a617202 136 Gene3D G3DSA:3.10.580.10 1 136 1.6E-45 T 31-10-2018 TK1036 7c2be6ed951b5376829b65428a617202 136 Pfam PF00571 CBS domain 72 124 3.5E-15 T 31-10-2018 IPR000644 CBS domain TK1036 7c2be6ed951b5376829b65428a617202 136 Pfam PF00571 CBS domain 10 61 4.0E-11 T 31-10-2018 IPR000644 CBS domain TK1464 cfc57e72796962d50b40ec18259e6fdd 273 SUPERFAMILY SSF53335 38 222 6.25E-18 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TK1464 cfc57e72796962d50b40ec18259e6fdd 273 Gene3D G3DSA:3.40.50.150 25 247 5.5E-20 T 31-10-2018 TK1464 cfc57e72796962d50b40ec18259e6fdd 273 Pfam PF01209 ubiE/COQ5 methyltransferase family 38 161 1.8E-6 T 31-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 TK1622 7f97489933fbed00b7b2985e774b5fa4 522 Pfam PF01039 Carboxyl transferase domain 28 520 3.3E-202 T 31-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 TK1622 7f97489933fbed00b7b2985e774b5fa4 522 SUPERFAMILY SSF52096 3 257 2.11E-79 T 31-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TK1622 7f97489933fbed00b7b2985e774b5fa4 522 SUPERFAMILY SSF52096 244 522 9.95E-93 T 31-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TK1622 7f97489933fbed00b7b2985e774b5fa4 522 Gene3D G3DSA:3.90.226.10 262 522 4.8E-96 T 31-10-2018 TK1622 7f97489933fbed00b7b2985e774b5fa4 522 Gene3D G3DSA:3.90.226.10 1 260 6.1E-99 T 31-10-2018 TK0178 e729a08def1d3548909d726cbe8fef99 661 Pfam PF13087 AAA domain 430 631 7.0E-58 T 31-10-2018 TK0178 e729a08def1d3548909d726cbe8fef99 661 Gene3D G3DSA:3.40.50.300 453 659 1.5E-62 T 31-10-2018 TK0178 e729a08def1d3548909d726cbe8fef99 661 Pfam PF13086 AAA domain 176 425 1.0E-54 T 31-10-2018 TK0178 e729a08def1d3548909d726cbe8fef99 661 SUPERFAMILY SSF52540 170 644 8.79E-64 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK0178 e729a08def1d3548909d726cbe8fef99 661 TIGRFAM TIGR00376 TIGR00376: putative DNA helicase 20 653 4.5E-251 T 31-10-2018 IPR004483 Helicase SMUBP-2/Hcs1-like GO:0003677|GO:0005524 TK1966 6a86e862d90e56465f8acff8c385ad65 304 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 190 212 - T 31-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site TK1966 6a86e862d90e56465f8acff8c385ad65 304 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 142 169 - T 31-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 TK1966 6a86e862d90e56465f8acff8c385ad65 304 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 105 280 9.4E-73 T 31-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 TK1966 6a86e862d90e56465f8acff8c385ad65 304 Gene3D G3DSA:3.40.50.720 7 298 3.4E-136 T 31-10-2018 TK1966 6a86e862d90e56465f8acff8c385ad65 304 Gene3D G3DSA:3.40.50.720 92 282 3.4E-136 T 31-10-2018 TK1966 6a86e862d90e56465f8acff8c385ad65 304 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 3 304 1.2E-40 T 31-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 TK1966 6a86e862d90e56465f8acff8c385ad65 304 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 219 235 - T 31-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site TK1966 6a86e862d90e56465f8acff8c385ad65 304 SUPERFAMILY SSF52283 1 133 5.29E-40 T 31-10-2018 TK1966 6a86e862d90e56465f8acff8c385ad65 304 SUPERFAMILY SSF51735 99 280 2.37E-67 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily TK2024 8f82e74c51e10e67f38df94585c53ac6 185 TIGRFAM TIGR00373 TIGR00373: transcription factor E 10 164 1.6E-48 T 31-10-2018 IPR016481 Transcription factor TFE, archaea GO:0006355 TK2024 8f82e74c51e10e67f38df94585c53ac6 185 PIRSF PIRSF006373 1 180 1.1E-71 T 31-10-2018 IPR016481 Transcription factor TFE, archaea GO:0006355 TK2024 8f82e74c51e10e67f38df94585c53ac6 185 Gene3D G3DSA:1.10.10.10 3 87 5.9E-27 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TK2024 8f82e74c51e10e67f38df94585c53ac6 185 SUPERFAMILY SSF46785 6 87 1.82E-23 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TK2024 8f82e74c51e10e67f38df94585c53ac6 185 Pfam PF02002 TFIIE alpha subunit 10 110 1.5E-24 T 31-10-2018 IPR024550 TFIIEalpha/SarR/Rpc3 HTH domain Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-674695|Reactome: R-HSA-6807505|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-76042 TK2024 8f82e74c51e10e67f38df94585c53ac6 185 SMART SM00531 19 158 6.0E-54 T 31-10-2018 IPR002853 Transcription initiation factor IIE subunit alpha, N-terminal GO:0006367 Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-674695|Reactome: R-HSA-6807505|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-76042 TK2024 8f82e74c51e10e67f38df94585c53ac6 185 Hamap MF_01909 Transcription factor E [tfe]. 3 166 27.081 T 31-10-2018 IPR016481 Transcription factor TFE, archaea GO:0006355 TK2300 2f719e0e7756d679a6fb94816beb0b42 118 SUPERFAMILY SSF102462 3 118 8.89E-43 T 31-10-2018 IPR023476 Peptidyl-tRNA hydrolase II domain superfamily MetaCyc: PWY-6308 TK2300 2f719e0e7756d679a6fb94816beb0b42 118 Hamap MF_00628 Peptidyl-tRNA hydrolase [pth]. 4 118 29.851 T 31-10-2018 IPR034759 Peptidyl-tRNA hydrolase, archaea GO:0004045 MetaCyc: PWY-6308 TK2300 2f719e0e7756d679a6fb94816beb0b42 118 Gene3D G3DSA:3.40.1490.10 1 118 1.5E-48 T 31-10-2018 IPR023476 Peptidyl-tRNA hydrolase II domain superfamily MetaCyc: PWY-6308 TK2300 2f719e0e7756d679a6fb94816beb0b42 118 Pfam PF01981 Peptidyl-tRNA hydrolase PTH2 4 118 5.5E-44 T 31-10-2018 IPR002833 Peptidyl-tRNA hydrolase, PTH2 GO:0004045 MetaCyc: PWY-6308 TK2300 2f719e0e7756d679a6fb94816beb0b42 118 TIGRFAM TIGR00283 arch_pth2: peptidyl-tRNA hydrolase 5 118 1.9E-42 T 31-10-2018 IPR002833 Peptidyl-tRNA hydrolase, PTH2 GO:0004045 MetaCyc: PWY-6308 TK1106 fbb50bd4f472b8f33e1a235101f4c7ea 267 Gene3D G3DSA:3.40.50.300 1 240 1.7E-70 T 31-10-2018 TK1106 fbb50bd4f472b8f33e1a235101f4c7ea 267 Pfam PF00005 ABC transporter 17 162 3.5E-28 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TK1106 fbb50bd4f472b8f33e1a235101f4c7ea 267 SUPERFAMILY SSF52540 1 226 6.21E-64 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK1106 fbb50bd4f472b8f33e1a235101f4c7ea 267 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TK1106 fbb50bd4f472b8f33e1a235101f4c7ea 267 TIGRFAM TIGR01166 cbiO: cobalt ABC transporter, ATP-binding protein 13 194 2.7E-67 T 31-10-2018 IPR005876 Cobalt transport protein ATP-binding subunit GO:0006824 TK1106 fbb50bd4f472b8f33e1a235101f4c7ea 267 SMART SM00382 26 217 9.1E-13 T 31-10-2018 IPR003593 AAA+ ATPase domain TK0679 6e8d0bfa444f12e2cb571af72737f444 221 TIGRFAM TIGR03724 arch_bud32: Kae1-associated kinase Bud32 4 214 1.6E-74 T 31-10-2018 IPR022495 Serine/threonine-protein kinase Bud32 GO:0004674 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6782315|Reactome: R-HSA-6804756 TK0679 6e8d0bfa444f12e2cb571af72737f444 221 ProSitePatterns PS00109 Tyrosine protein kinases specific active-site signature. 125 137 - T 31-10-2018 IPR008266 Tyrosine-protein kinase, active site GO:0004672|GO:0006468 TK0679 6e8d0bfa444f12e2cb571af72737f444 221 SMART SM00220 25 220 4.6E-4 T 31-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TK0679 6e8d0bfa444f12e2cb571af72737f444 221 SUPERFAMILY SSF56112 2 159 1.89E-29 T 31-10-2018 IPR011009 Protein kinase-like domain superfamily TK0679 6e8d0bfa444f12e2cb571af72737f444 221 Pfam PF01163 RIO1 family 47 148 4.9E-16 T 31-10-2018 TK0679 6e8d0bfa444f12e2cb571af72737f444 221 Gene3D G3DSA:1.10.510.10 96 216 2.1E-33 T 31-10-2018 TK0679 6e8d0bfa444f12e2cb571af72737f444 221 Gene3D G3DSA:3.30.200.20 9 89 1.3E-25 T 31-10-2018 TK0405 4294e52d03d2eea431de1b800ba05784 139 SMART SM00966 65 106 0.38 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 TK0405 4294e52d03d2eea431de1b800ba05784 139 SMART SM00966 13 51 0.67 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 TK0405 4294e52d03d2eea431de1b800ba05784 139 SUPERFAMILY SSF89447 12 44 3.01E-5 T 31-10-2018 IPR037914 SpoVT-AbrB domain superfamily TK0405 4294e52d03d2eea431de1b800ba05784 139 SUPERFAMILY SSF89447 63 97 8.55E-6 T 31-10-2018 IPR037914 SpoVT-AbrB domain superfamily TK0405 4294e52d03d2eea431de1b800ba05784 139 Gene3D G3DSA:2.10.260.10 5 103 2.7E-24 T 31-10-2018 TK1400 c647735a64f7f1bf5086ee7f4e0e0a88 443 SUPERFAMILY SSF103473 16 435 1.57E-40 T 31-10-2018 IPR036259 MFS transporter superfamily TK1400 c647735a64f7f1bf5086ee7f4e0e0a88 443 Pfam PF13347 MFS/sugar transport protein 50 405 2.9E-13 T 31-10-2018 TK1400 c647735a64f7f1bf5086ee7f4e0e0a88 443 Gene3D G3DSA:1.20.1250.20 12 289 1.1E-17 T 31-10-2018 TK1400 c647735a64f7f1bf5086ee7f4e0e0a88 443 Gene3D G3DSA:1.20.1250.20 290 442 5.4E-15 T 31-10-2018 TK0039 9b614e3da88429c4f48232f30db6a1bc 580 TIGRFAM TIGR02537 arch_flag_Nterm: archaeal flagellin N-terminal-like domain 7 30 3.3E-5 T 31-10-2018 IPR013373 Flagellin/pilin, N-terminal TK0039 9b614e3da88429c4f48232f30db6a1bc 580 Pfam PF01917 Archaebacterial flagellin 9 129 1.4E-34 T 31-10-2018 IPR002774 Flagellin, archaea GO:0005198|GO:0006928 TK2151 3cf116c4720cb4839d15a1d325153f02 151 PIRSF PIRSF004932 1 149 9.1E-70 T 31-10-2018 IPR018384 DNA-binding protein Tfx, euryarchaeota GO:0003677 TK2151 3cf116c4720cb4839d15a1d325153f02 151 Pfam PF04545 Sigma-70, region 4 5 47 2.0E-7 T 31-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 TK2151 3cf116c4720cb4839d15a1d325153f02 151 SUPERFAMILY SSF89915 15 127 1.24E-23 T 31-10-2018 IPR036657 DNA-binding protein Tfx superfamily, archaea GO:0003677 TK2151 3cf116c4720cb4839d15a1d325153f02 151 Pfam PF14601 DNA_binding protein, TFX, C-term 50 130 2.1E-24 T 31-10-2018 IPR029291 DNA binding protein Tfx, C-terminal TK2151 3cf116c4720cb4839d15a1d325153f02 151 Hamap MF_00620 Putative transcriptional regulatory protein . 1 133 30.142 T 31-10-2018 IPR018384 DNA-binding protein Tfx, euryarchaeota GO:0003677 TK2151 3cf116c4720cb4839d15a1d325153f02 151 SMART SM00421 2 59 0.0041 T 31-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TK2151 3cf116c4720cb4839d15a1d325153f02 151 TIGRFAM TIGR00721 tfx: DNA-binding protein, Tfx family 1 135 3.4E-59 T 31-10-2018 IPR004645 DNA-binding protein Tfx, archaea GO:0003677 TK2151 3cf116c4720cb4839d15a1d325153f02 151 Gene3D G3DSA:3.30.1190.10 15 133 2.0E-38 T 31-10-2018 IPR036657 DNA-binding protein Tfx superfamily, archaea GO:0003677 TK0884 8986502d22114c79e751a077671e1e30 439 Pfam PF00999 Sodium/hydrogen exchanger family 12 404 7.5E-45 T 31-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 TK0884 8986502d22114c79e751a077671e1e30 439 Gene3D G3DSA:1.20.1530.20 5 417 5.6E-67 T 31-10-2018 IPR038770 Sodium/solute symporter superfamily TK0664 792886878f955e1395b2b4ea16178bf1 215 Gene3D G3DSA:3.40.50.2020 6 181 4.0E-42 T 31-10-2018 TK0664 792886878f955e1395b2b4ea16178bf1 215 Pfam PF00156 Phosphoribosyl transferase domain 11 152 1.3E-22 T 31-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 TK0664 792886878f955e1395b2b4ea16178bf1 215 SUPERFAMILY SSF53271 8 163 3.41E-37 T 31-10-2018 IPR029057 Phosphoribosyltransferase-like TK2061 66cf28957ba3a28549a384da44df4267 406 Pfam PF01384 Phosphate transporter family 22 395 2.0E-110 T 31-10-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 TK0839 192425161e40f7eba51351f634b4df71 196 TIGRFAM TIGR03605 antibiot_sagB: SagB-type dehydrogenase domain 35 192 2.0E-49 T 31-10-2018 IPR020051 SagB-type dehydrogenase domain TK0839 192425161e40f7eba51351f634b4df71 196 Pfam PF00881 Nitroreductase family 23 192 5.4E-36 T 31-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 TK0839 192425161e40f7eba51351f634b4df71 196 Gene3D G3DSA:3.40.109.10 1 195 1.3E-75 T 31-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 TK0839 192425161e40f7eba51351f634b4df71 196 SUPERFAMILY SSF55469 14 195 2.9E-40 T 31-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 TK2060 882dba795af99bb94d36b76ead5576df 224 TIGRFAM TIGR00153 TIGR00153: TIGR00153 family protein 5 222 1.2E-34 T 31-10-2018 IPR002727 Protein of unknown function DUF47 TK2060 882dba795af99bb94d36b76ead5576df 224 SUPERFAMILY SSF109755 25 221 1.78E-19 T 31-10-2018 TK2060 882dba795af99bb94d36b76ead5576df 224 Gene3D G3DSA:1.20.58.220 1 224 4.4E-50 T 31-10-2018 IPR038078 PhoU-like domain superfamily TK2060 882dba795af99bb94d36b76ead5576df 224 Pfam PF01865 Protein of unknown function DUF47 6 222 1.7E-46 T 31-10-2018 IPR018445 Putative phosphate transport regulator TK1493 ac425ae99bc6ebe7a41f3de32941ef4b 99 Pfam PF04930 FUN14 family 12 96 3.1E-13 T 31-10-2018 IPR007014 FUN14 TK1711 d9adcd27ef3d47d33b37f9a8cad36426 331 Pfam PF00483 Nucleotidyl transferase 2 234 2.7E-37 T 31-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 TK1711 d9adcd27ef3d47d33b37f9a8cad36426 331 Gene3D G3DSA:2.160.10.10 239 330 9.9E-7 T 31-10-2018 TK1711 d9adcd27ef3d47d33b37f9a8cad36426 331 SUPERFAMILY SSF53448 1 286 1.15E-55 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TK1711 d9adcd27ef3d47d33b37f9a8cad36426 331 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 253 281 0.001 T 31-10-2018 IPR001451 Hexapeptide repeat TK1711 d9adcd27ef3d47d33b37f9a8cad36426 331 Gene3D G3DSA:3.90.550.10 1 238 3.9E-54 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TK0244 45e2d3ecfdd3eb49126693df3c569e06 376 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 8 251 1.6E-93 T 31-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 TK0244 45e2d3ecfdd3eb49126693df3c569e06 376 Pfam PF00815 Histidinol dehydrogenase 255 375 1.0E-40 T 31-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 TK0244 45e2d3ecfdd3eb49126693df3c569e06 376 Pfam PF00815 Histidinol dehydrogenase 4 250 1.2E-90 T 31-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 TK0244 45e2d3ecfdd3eb49126693df3c569e06 376 SUPERFAMILY SSF53720 6 375 1.28E-59 T 31-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 TK0244 45e2d3ecfdd3eb49126693df3c569e06 376 Gene3D G3DSA:3.40.50.1980 248 320 8.4E-21 T 31-10-2018 TK0244 45e2d3ecfdd3eb49126693df3c569e06 376 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 1 376 36.834 T 31-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 TK0244 45e2d3ecfdd3eb49126693df3c569e06 376 ProSitePatterns PS00611 Histidinol dehydrogenase signature. 198 230 - T 31-10-2018 IPR001692 Histidinol dehydrogenase, conserved site GO:0000105|GO:0004399|GO:0055114 KEGG: 00340+1.1.1.23 TK0244 45e2d3ecfdd3eb49126693df3c569e06 376 Gene3D G3DSA:3.40.50.1980 1 211 2.6E-68 T 31-10-2018 TK0244 45e2d3ecfdd3eb49126693df3c569e06 376 PRINTS PR00083 Histidinol dehydrogenase signature 269 294 3.2E-97 T 31-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 TK0244 45e2d3ecfdd3eb49126693df3c569e06 376 PRINTS PR00083 Histidinol dehydrogenase signature 106 132 3.2E-97 T 31-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 TK0244 45e2d3ecfdd3eb49126693df3c569e06 376 PRINTS PR00083 Histidinol dehydrogenase signature 169 194 3.2E-97 T 31-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 TK0244 45e2d3ecfdd3eb49126693df3c569e06 376 PRINTS PR00083 Histidinol dehydrogenase signature 310 328 3.2E-97 T 31-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 TK0244 45e2d3ecfdd3eb49126693df3c569e06 376 PRINTS PR00083 Histidinol dehydrogenase signature 8 32 3.2E-97 T 31-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 TK0244 45e2d3ecfdd3eb49126693df3c569e06 376 PRINTS PR00083 Histidinol dehydrogenase signature 79 106 3.2E-97 T 31-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 TK0244 45e2d3ecfdd3eb49126693df3c569e06 376 PRINTS PR00083 Histidinol dehydrogenase signature 198 219 3.2E-97 T 31-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 TK0244 45e2d3ecfdd3eb49126693df3c569e06 376 PRINTS PR00083 Histidinol dehydrogenase signature 140 166 3.2E-97 T 31-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 TK0244 45e2d3ecfdd3eb49126693df3c569e06 376 PRINTS PR00083 Histidinol dehydrogenase signature 220 239 3.2E-97 T 31-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 TK1469 4458b64e6bfd5eb23324d21d72a82edb 444 SUPERFAMILY SSF56281 2 443 6.18E-65 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TK1469 4458b64e6bfd5eb23324d21d72a82edb 444 Gene3D G3DSA:3.60.15.10 3 443 1.4E-135 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TK1469 4458b64e6bfd5eb23324d21d72a82edb 444 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 375 425 2.5E-13 T 31-10-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain TK1469 4458b64e6bfd5eb23324d21d72a82edb 444 Pfam PF00753 Metallo-beta-lactamase superfamily 26 187 8.4E-13 T 31-10-2018 IPR001279 Metallo-beta-lactamase TK1469 4458b64e6bfd5eb23324d21d72a82edb 444 ProSitePatterns PS01292 Uncharacterized protein family UPF0036 signature. 382 410 - T 31-10-2018 IPR001587 Ribonuclease J, conserved site TK1469 4458b64e6bfd5eb23324d21d72a82edb 444 Gene3D G3DSA:3.40.50.10710 219 378 1.4E-135 T 31-10-2018 TK1469 4458b64e6bfd5eb23324d21d72a82edb 444 TIGRFAM TIGR00649 MG423: beta-CASP ribonuclease, RNase J family 2 444 5.9E-157 T 31-10-2018 IPR004613 Ribonuclease J GO:0003723|GO:0046872 TK1469 4458b64e6bfd5eb23324d21d72a82edb 444 SMART SM00849 14 225 6.6E-22 T 31-10-2018 IPR001279 Metallo-beta-lactamase TK1469 4458b64e6bfd5eb23324d21d72a82edb 444 Hamap MF_01492 Ribonuclease J [rnj]. 1 444 49.073 T 31-10-2018 IPR030879 Ribonuclease J, archaea GO:0003723|GO:0004534|GO:0090503 TK0406 a6177a37398678e10bfff0c6c425e365 141 Gene3D G3DSA:2.10.260.10 5 101 3.5E-24 T 31-10-2018 TK0406 a6177a37398678e10bfff0c6c425e365 141 SUPERFAMILY SSF89447 12 44 1.22E-5 T 31-10-2018 IPR037914 SpoVT-AbrB domain superfamily TK0406 a6177a37398678e10bfff0c6c425e365 141 PIRSF PIRSF019240 1 135 4.8E-24 T 31-10-2018 IPR016752 Uncharacterised conserved protein UCP019240, SpoVT/AbrB-related TK0406 a6177a37398678e10bfff0c6c425e365 141 SMART SM00966 13 54 0.13 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 TK0406 a6177a37398678e10bfff0c6c425e365 141 SMART SM00966 63 109 0.016 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 TK0477 9395557761e3b25a5c0cc6176a351d71 217 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 103 182 1.0E-12 T 31-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TK0477 9395557761e3b25a5c0cc6176a351d71 217 Pfam PF13419 Haloacid dehalogenase-like hydrolase 7 188 2.0E-32 T 31-10-2018 TK0477 9395557761e3b25a5c0cc6176a351d71 217 Gene3D G3DSA:1.10.150.520 18 89 2.1E-49 T 31-10-2018 TK0477 9395557761e3b25a5c0cc6176a351d71 217 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 101 114 4.6E-17 T 31-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TK0477 9395557761e3b25a5c0cc6176a351d71 217 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 4 15 4.6E-17 T 31-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TK0477 9395557761e3b25a5c0cc6176a351d71 217 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 131 147 4.6E-17 T 31-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TK0477 9395557761e3b25a5c0cc6176a351d71 217 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 149 169 4.6E-17 T 31-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TK0477 9395557761e3b25a5c0cc6176a351d71 217 ProSitePatterns PS01228 Hypothetical cof family signature 1. 6 17 - T 31-10-2018 TK0477 9395557761e3b25a5c0cc6176a351d71 217 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 83 188 7.3E-14 T 31-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TK0477 9395557761e3b25a5c0cc6176a351d71 217 SUPERFAMILY SSF56784 1 209 7.13E-51 T 31-10-2018 IPR036412 HAD-like superfamily TK0477 9395557761e3b25a5c0cc6176a351d71 217 TIGRFAM TIGR02253 CTE7: HAD hydrolase, TIGR02253 family 4 209 1.8E-51 T 31-10-2018 IPR011950 HAD-superfamily hydrolase, subfamily IA, CTE7 GO:0016787 Reactome: R-HSA-4085001 TK0477 9395557761e3b25a5c0cc6176a351d71 217 Gene3D G3DSA:3.40.50.1000 5 209 2.1E-49 T 31-10-2018 IPR023214 HAD superfamily TK0159 14b1e303d3ff47bbe73529b2ca0c007b 564 SUPERFAMILY SSF161098 313 558 1.7E-55 T 31-10-2018 IPR035906 MetI-like superfamily TK0159 14b1e303d3ff47bbe73529b2ca0c007b 564 Gene3D G3DSA:1.10.3720.10 28 288 9.0E-59 T 31-10-2018 IPR035906 MetI-like superfamily TK0159 14b1e303d3ff47bbe73529b2ca0c007b 564 Gene3D G3DSA:1.10.3720.10 311 562 9.3E-57 T 31-10-2018 IPR035906 MetI-like superfamily TK0159 14b1e303d3ff47bbe73529b2ca0c007b 564 SUPERFAMILY SSF161098 26 281 1.44E-50 T 31-10-2018 IPR035906 MetI-like superfamily TK0159 14b1e303d3ff47bbe73529b2ca0c007b 564 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 386 555 2.3E-14 T 31-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TK0159 14b1e303d3ff47bbe73529b2ca0c007b 564 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 97 279 1.9E-15 T 31-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TK1250 eab739b15532d0b4b5ef383947fc61aa 304 SUPERFAMILY SSF55608 67 149 8.08E-11 T 31-10-2018 IPR027434 Homing endonuclease TK1250 eab739b15532d0b4b5ef383947fc61aa 304 Pfam PF14528 LAGLIDADG-like domain 164 258 3.5E-18 T 31-10-2018 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 TK1250 eab739b15532d0b4b5ef383947fc61aa 304 SUPERFAMILY SSF55608 154 276 1.33E-9 T 31-10-2018 IPR027434 Homing endonuclease TK1250 eab739b15532d0b4b5ef383947fc61aa 304 Gene3D G3DSA:3.10.28.10 72 237 2.4E-14 T 31-10-2018 IPR027434 Homing endonuclease TK0690 580a2afd688218b5bb4d8ab7e01cbbd1 646 Pfam PF01568 Molydopterin dinucleotide binding domain 527 629 3.6E-22 T 31-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 TK0690 580a2afd688218b5bb4d8ab7e01cbbd1 646 SUPERFAMILY SSF53706 3 518 3.01E-138 T 31-10-2018 TK0690 580a2afd688218b5bb4d8ab7e01cbbd1 646 Gene3D G3DSA:2.40.40.20 517 640 2.6E-30 T 31-10-2018 TK0690 580a2afd688218b5bb4d8ab7e01cbbd1 646 Gene3D G3DSA:3.40.228.10 133 505 3.5E-122 T 31-10-2018 TK0690 580a2afd688218b5bb4d8ab7e01cbbd1 646 Gene3D G3DSA:3.40.50.740 67 450 3.5E-122 T 31-10-2018 TK0690 580a2afd688218b5bb4d8ab7e01cbbd1 646 SMART SM00926 1 53 2.1E-6 T 31-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TK0690 580a2afd688218b5bb4d8ab7e01cbbd1 646 Gene3D G3DSA:2.20.25.90 2 58 3.6E-10 T 31-10-2018 TK0690 580a2afd688218b5bb4d8ab7e01cbbd1 646 Pfam PF00384 Molybdopterin oxidoreductase 56 423 3.0E-46 T 31-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TK0690 580a2afd688218b5bb4d8ab7e01cbbd1 646 ProSitePatterns PS00932 Prokaryotic molybdopterin oxidoreductases signature 3. 558 585 - T 31-10-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 TK0690 580a2afd688218b5bb4d8ab7e01cbbd1 646 SUPERFAMILY SSF50692 516 636 2.69E-33 T 31-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily TK0690 580a2afd688218b5bb4d8ab7e01cbbd1 646 Gene3D G3DSA:3.30.2070.10 407 487 3.5E-122 T 31-10-2018 TK0690 580a2afd688218b5bb4d8ab7e01cbbd1 646 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 4 47 3.1E-6 T 31-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TK1195 1dfd9a26a73e76f6e8d350a7fb51d5a2 95 Gene3D G3DSA:1.20.1270.90 5 85 4.3E-25 T 31-10-2018 TK1195 1dfd9a26a73e76f6e8d350a7fb51d5a2 95 Pfam PF04010 Protein of unknown function (DUF357) 12 84 6.8E-30 T 31-10-2018 IPR023140 Domain of unknown function DUF357 TK1195 1dfd9a26a73e76f6e8d350a7fb51d5a2 95 SUPERFAMILY SSF158372 5 85 3.14E-26 T 31-10-2018 IPR036809 AF1782-like superfamily TK2145 49c360df175128227143f14ec7471a34 590 Gene3D G3DSA:3.20.20.70 127 401 2.2E-33 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TK2145 49c360df175128227143f14ec7471a34 590 Pfam PF13353 4Fe-4S single cluster domain 143 226 4.8E-6 T 31-10-2018 TK2145 49c360df175128227143f14ec7471a34 590 SUPERFAMILY SSF102114 128 396 8.11E-44 T 31-10-2018 TK2145 49c360df175128227143f14ec7471a34 590 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 145 156 - T 31-10-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TK2145 49c360df175128227143f14ec7471a34 590 Pfam PF04055 Radical SAM superfamily 143 302 6.9E-22 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TK0027 bd017f80b356689a0aeb3895d52b9e1c 218 TIGRFAM TIGR00104 tRNA_TsaA: tRNA-Thr(GGU) m(6)t(6)A37 methyltransferase TsaA 21 132 7.1E-35 T 31-10-2018 IPR023370 YaeB-like, N-terminal domain TK0027 bd017f80b356689a0aeb3895d52b9e1c 218 SUPERFAMILY SSF118196 6 141 4.05E-39 T 31-10-2018 IPR036413 YaeB-like superfamily TK0027 bd017f80b356689a0aeb3895d52b9e1c 218 Gene3D G3DSA:2.40.30.70 12 146 3.5E-32 T 31-10-2018 IPR036414 YaeB, N-terminal domain superfamily TK0027 bd017f80b356689a0aeb3895d52b9e1c 218 Pfam PF01980 Uncharacterised protein family UPF0066 20 128 4.1E-30 T 31-10-2018 IPR023370 YaeB-like, N-terminal domain TK0027 bd017f80b356689a0aeb3895d52b9e1c 218 ProSitePatterns PS01318 TsaA-like domain signature. 76 87 - T 31-10-2018 IPR023368 Uncharacterised protein family UPF0066, conserved site TK1316 7a62f23345e32ec92b1046d266e88aaf 317 Gene3D G3DSA:3.30.479.30 50 181 6.1E-52 T 31-10-2018 TK1316 7a62f23345e32ec92b1046d266e88aaf 317 Pfam PF01145 SPFH domain / Band 7 family 26 195 1.4E-41 T 31-10-2018 IPR001107 Band 7 domain TK1316 7a62f23345e32ec92b1046d266e88aaf 317 SMART SM00244 22 179 4.3E-73 T 31-10-2018 IPR001107 Band 7 domain TK1316 7a62f23345e32ec92b1046d266e88aaf 317 SUPERFAMILY SSF117892 53 186 2.09E-46 T 31-10-2018 IPR036013 Band 7/SPFH domain superfamily TK1316 7a62f23345e32ec92b1046d266e88aaf 317 ProSitePatterns PS01270 Band 7 protein family signature. 135 163 - T 31-10-2018 IPR018080 Band 7/stomatin-like, conserved site TK1316 7a62f23345e32ec92b1046d266e88aaf 317 PRINTS PR00721 Stomatin signature 174 195 4.8E-35 T 31-10-2018 IPR001972 Stomatin family GO:0016020 TK1316 7a62f23345e32ec92b1046d266e88aaf 317 PRINTS PR00721 Stomatin signature 131 154 4.8E-35 T 31-10-2018 IPR001972 Stomatin family GO:0016020 TK1316 7a62f23345e32ec92b1046d266e88aaf 317 PRINTS PR00721 Stomatin signature 111 128 4.8E-35 T 31-10-2018 IPR001972 Stomatin family GO:0016020 TK1316 7a62f23345e32ec92b1046d266e88aaf 317 PRINTS PR00721 Stomatin signature 76 97 4.8E-35 T 31-10-2018 IPR001972 Stomatin family GO:0016020 TK1316 7a62f23345e32ec92b1046d266e88aaf 317 PRINTS PR00721 Stomatin signature 29 51 4.8E-35 T 31-10-2018 IPR001972 Stomatin family GO:0016020 TK1316 7a62f23345e32ec92b1046d266e88aaf 317 PRINTS PR00721 Stomatin signature 155 173 4.8E-35 T 31-10-2018 IPR001972 Stomatin family GO:0016020 TK1673 bb95b2ed9bdaebc10b932a04af9cb4c2 194 Gene3D G3DSA:3.40.50.150 15 194 3.1E-41 T 31-10-2018 TK1673 bb95b2ed9bdaebc10b932a04af9cb4c2 194 TIGRFAM TIGR00537 hemK_rel_arch: putative methylase 16 191 4.3E-60 T 31-10-2018 IPR004557 Eukaryotic/archaeal PrmC-related GO:0008276 Reactome: R-HSA-156581|Reactome: R-HSA-72764 TK1673 bb95b2ed9bdaebc10b932a04af9cb4c2 194 SUPERFAMILY SSF53335 3 181 1.01E-39 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TK1673 bb95b2ed9bdaebc10b932a04af9cb4c2 194 Pfam PF05175 Methyltransferase small domain 23 177 9.4E-17 T 31-10-2018 IPR007848 Methyltransferase small domain GO:0008168 TK1932 d45dfcca078cd784682b504fb6489f54 448 PIRSF PIRSF039117 1 448 1.1E-131 T 31-10-2018 IPR030665 Circadian clock protein kinase KaiC KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1 TK1932 d45dfcca078cd784682b504fb6489f54 448 Gene3D G3DSA:3.40.50.300 228 448 4.4E-50 T 31-10-2018 TK1932 d45dfcca078cd784682b504fb6489f54 448 PRINTS PR01874 DNA repair protein radA signature 247 275 7.2E-9 T 31-10-2018 TK1932 d45dfcca078cd784682b504fb6489f54 448 PRINTS PR01874 DNA repair protein radA signature 289 306 7.2E-9 T 31-10-2018 TK1932 d45dfcca078cd784682b504fb6489f54 448 SUPERFAMILY SSF52540 2 224 3.13E-38 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK1932 d45dfcca078cd784682b504fb6489f54 448 Pfam PF06745 KaiC 239 447 9.5E-30 T 31-10-2018 IPR014774 KaiC-like domain TK1932 d45dfcca078cd784682b504fb6489f54 448 Pfam PF06745 KaiC 4 222 2.2E-49 T 31-10-2018 IPR014774 KaiC-like domain TK1932 d45dfcca078cd784682b504fb6489f54 448 Gene3D G3DSA:3.40.50.300 1 224 3.0E-50 T 31-10-2018 TK1932 d45dfcca078cd784682b504fb6489f54 448 SMART SM00382 255 436 4.7E-7 T 31-10-2018 IPR003593 AAA+ ATPase domain TK1932 d45dfcca078cd784682b504fb6489f54 448 SMART SM00382 21 185 0.0025 T 31-10-2018 IPR003593 AAA+ ATPase domain TK1932 d45dfcca078cd784682b504fb6489f54 448 SUPERFAMILY SSF52540 235 447 1.64E-40 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK1804 1951eda06ffda915c1ecebb6dc64304d 815 Gene3D G3DSA:3.10.105.10 434 633 1.5E-15 T 31-10-2018 TK1804 1951eda06ffda915c1ecebb6dc64304d 815 SUPERFAMILY SSF53850 135 620 4.52E-26 T 31-10-2018 TK1804 1951eda06ffda915c1ecebb6dc64304d 815 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 135 599 4.5E-25 T 31-10-2018 IPR000914 Solute-binding protein family 5 domain TK1804 1951eda06ffda915c1ecebb6dc64304d 815 TIGRFAM TIGR04288 CGP_CTERM: CGP-CTERM domain 795 814 4.3E-8 T 31-10-2018 IPR027552 CGP-CTERM domain TK1804 1951eda06ffda915c1ecebb6dc64304d 815 Gene3D G3DSA:3.40.190.10 297 433 2.0E-10 T 31-10-2018 TK1747 7fa4aa2e96fcd25842735eddbe48a862 178 SUPERFAMILY SSF52972 1 176 6.1E-52 T 31-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like TK1747 7fa4aa2e96fcd25842735eddbe48a862 178 TIGRFAM TIGR00258 TIGR00258: inosine/xanthosine triphosphatase 5 176 6.7E-57 T 31-10-2018 IPR002786 Non-canonical purine NTP phosphatase TK1747 7fa4aa2e96fcd25842735eddbe48a862 178 Hamap MF_00648 Non-canonical purine NTP phosphatase. 1 176 36.675 T 31-10-2018 IPR002786 Non-canonical purine NTP phosphatase TK1747 7fa4aa2e96fcd25842735eddbe48a862 178 Gene3D G3DSA:3.90.950.10 1 177 3.0E-57 T 31-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like TK1747 7fa4aa2e96fcd25842735eddbe48a862 178 Pfam PF01931 Protein of unknown function DUF84 6 170 1.9E-54 T 31-10-2018 IPR026533 Non-canonical purine NTP phosphatase/PRRC1 TK0778 7197dc1e689e9173ffc3d14ca4666301 303 PIRSF PIRSF016662 1 291 9.2E-113 T 31-10-2018 IPR014481 Uncharacterised conserved protein UCP016662, toprim-type TK0778 7197dc1e689e9173ffc3d14ca4666301 303 Pfam PF01751 Toprim domain 8 88 4.5E-8 T 31-10-2018 IPR006171 TOPRIM domain TK0778 7197dc1e689e9173ffc3d14ca4666301 303 SMART SM00493 5 84 1.0E-7 T 31-10-2018 IPR006171 TOPRIM domain TK0778 7197dc1e689e9173ffc3d14ca4666301 303 Gene3D G3DSA:3.40.1360.10 4 107 1.2E-6 T 31-10-2018 TK1122 3fcad8721a573e5fa78a392c4bbb410a 112 Pfam PF01920 Prefoldin subunit 21 110 2.3E-11 T 31-10-2018 IPR002777 Prefoldin beta-like GO:0006457|GO:0016272|GO:0051082 Reactome: R-HSA-389957 TK1122 3fcad8721a573e5fa78a392c4bbb410a 112 Gene3D G3DSA:1.10.287.370 14 112 9.1E-46 T 31-10-2018 IPR009053 Prefoldin TK1122 3fcad8721a573e5fa78a392c4bbb410a 112 SUPERFAMILY SSF46579 18 110 5.36E-14 T 31-10-2018 TK1592 84af3a93bcd2d51c48c889cebfa1cb56 143 Hamap MF_00464 S-adenosylmethionine decarboxylase proenzyme [speH]. 4 120 31.447 T 31-10-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 TK1592 84af3a93bcd2d51c48c889cebfa1cb56 143 Gene3D G3DSA:3.30.160.750 66 129 7.8E-25 T 31-10-2018 TK1592 84af3a93bcd2d51c48c889cebfa1cb56 143 Gene3D G3DSA:3.30.360.110 4 65 8.4E-19 T 31-10-2018 TK1592 84af3a93bcd2d51c48c889cebfa1cb56 143 SUPERFAMILY SSF56276 6 120 3.73E-43 T 31-10-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 TK1592 84af3a93bcd2d51c48c889cebfa1cb56 143 TIGRFAM TIGR03330 SAM_DCase_Bsu: S-adenosylmethionine decarboxylase proenzyme 6 116 8.2E-45 T 31-10-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 TK1592 84af3a93bcd2d51c48c889cebfa1cb56 143 Pfam PF02675 S-adenosylmethionine decarboxylase 10 116 8.6E-39 T 31-10-2018 IPR003826 S-adenosylmethionine decarboxylase family, prokaryotic GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 TK2181 209df1b74998f36cd71d97e378888a00 418 SUPERFAMILY SSF69318 63 200 4.05E-8 T 31-10-2018 TK1067 7eee80af14282e219af6948849753f43 412 Hamap MF_02096 DNA repair protein. 1 406 40.441 T 31-10-2018 IPR033167 Archaeal Nre GO:0006281 TK1067 7eee80af14282e219af6948849753f43 412 Pfam PF04894 Archaeal Nre, N-terminal 19 284 2.2E-104 T 31-10-2018 IPR006978 Archaeal Nre, N-terminal TK1067 7eee80af14282e219af6948849753f43 412 Pfam PF04895 Archaeal Nre, C-terminal 296 406 6.6E-38 T 31-10-2018 IPR006979 Archaeal Nre, C-terminal TK0174 64268af1b1060cc19cddb65f3eecf9fc 205 TIGRFAM TIGR04335 AmmeMemoSam_A: AmmeMemoRadiSam system protein A 11 190 1.3E-57 T 31-10-2018 IPR027623 AmmeMemoRadiSam system protein A TK0174 64268af1b1060cc19cddb65f3eecf9fc 205 Hamap MF_00645 Protein . 5 188 41.058 T 31-10-2018 IPR023472 Uncharacterised protein family MJ0810 TK0174 64268af1b1060cc19cddb65f3eecf9fc 205 SUPERFAMILY SSF143447 4 202 3.4E-69 T 31-10-2018 IPR036071 AMMECR1 domain superfamily TK0174 64268af1b1060cc19cddb65f3eecf9fc 205 TIGRFAM TIGR00296 TIGR00296: uncharacterized protein, PH0010 family 4 197 6.2E-69 T 31-10-2018 IPR023473 AMMECR1 TK0174 64268af1b1060cc19cddb65f3eecf9fc 205 Gene3D G3DSA:3.30.1490.150 113 186 7.1E-73 T 31-10-2018 TK0174 64268af1b1060cc19cddb65f3eecf9fc 205 Gene3D G3DSA:3.30.700.20 6 197 7.1E-73 T 31-10-2018 IPR027485 AMMECR1, N-terminal TK0174 64268af1b1060cc19cddb65f3eecf9fc 205 Pfam PF01871 AMMECR1 13 190 2.1E-53 T 31-10-2018 IPR002733 AMMECR1 domain TK0944 4e25e31fc7ed8f40ab9c58b995158669 474 SUPERFAMILY SSF51735 9 141 6.74E-39 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily TK0944 4e25e31fc7ed8f40ab9c58b995158669 474 SUPERFAMILY SSF52210 311 468 3.66E-41 T 31-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TK0944 4e25e31fc7ed8f40ab9c58b995158669 474 Gene3D G3DSA:3.40.50.261 308 472 2.0E-51 T 31-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TK0944 4e25e31fc7ed8f40ab9c58b995158669 474 SUPERFAMILY SSF52210 143 304 2.09E-45 T 31-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TK0944 4e25e31fc7ed8f40ab9c58b995158669 474 Gene3D G3DSA:3.40.50.261 142 306 5.4E-61 T 31-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TK0944 4e25e31fc7ed8f40ab9c58b995158669 474 Pfam PF13380 CoA binding domain 16 145 1.0E-25 T 31-10-2018 IPR003781 CoA-binding GO:0048037 TK0944 4e25e31fc7ed8f40ab9c58b995158669 474 SMART SM00881 12 111 3.6E-37 T 31-10-2018 IPR003781 CoA-binding GO:0048037 TK0944 4e25e31fc7ed8f40ab9c58b995158669 474 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 167 303 5.6E-57 T 31-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain TK0944 4e25e31fc7ed8f40ab9c58b995158669 474 Gene3D G3DSA:3.40.50.720 6 140 5.2E-44 T 31-10-2018 TK2015 57e6d52d8f19b639edf88bbb74217dc5 330 Gene3D G3DSA:1.50.10.150 3 328 9.1E-45 T 31-10-2018 IPR038665 Voltage-dependent anion channel superfamily TK2015 57e6d52d8f19b639edf88bbb74217dc5 330 Pfam PF03595 Voltage-dependent anion channel 8 324 5.0E-73 T 31-10-2018 IPR004695 Voltage-dependent anion channel GO:0016021|GO:0055085 TK2015 57e6d52d8f19b639edf88bbb74217dc5 330 TIGRFAM TIGR00816 tdt: C4-dicarboxylate transporter/malic acid transport protein 8 324 8.0E-90 T 31-10-2018 IPR011552 Tellurite resistance protein TehA/malic acid transport protein GO:0016021 TK2213 87c3ddcbefd05f2f74563c89bd86cc7d 592 SUPERFAMILY SSF52540 148 548 2.94E-40 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK2213 87c3ddcbefd05f2f74563c89bd86cc7d 592 Pfam PF01935 Domain of unknown function DUF87 156 382 6.6E-54 T 31-10-2018 IPR002789 Helicase HerA, central domain TK2213 87c3ddcbefd05f2f74563c89bd86cc7d 592 Pfam PF09378 HAS barrel domain 11 116 8.0E-23 T 31-10-2018 IPR018538 Helicase HerA, barrel domain TK2213 87c3ddcbefd05f2f74563c89bd86cc7d 592 Gene3D G3DSA:3.40.50.300 142 304 3.3E-22 T 31-10-2018 TK0998 70b1106a5a64436092263ca8961eb2ed 135 Pfam PF01850 PIN domain 4 127 3.6E-23 T 31-10-2018 IPR002716 PIN domain TK0998 70b1106a5a64436092263ca8961eb2ed 135 Gene3D G3DSA:3.40.50.1010 3 132 2.3E-19 T 31-10-2018 TK0998 70b1106a5a64436092263ca8961eb2ed 135 SMART SM00670 1 125 2.7E-11 T 31-10-2018 IPR002716 PIN domain TK0998 70b1106a5a64436092263ca8961eb2ed 135 SUPERFAMILY SSF88723 1 133 2.8E-25 T 31-10-2018 IPR029060 PIN-like domain superfamily TK2057 5adca5d215dcc4d95e1b9c2885d7faa1 394 SUPERFAMILY SSF161098 179 378 8.24E-21 T 31-10-2018 IPR035906 MetI-like superfamily TK2057 5adca5d215dcc4d95e1b9c2885d7faa1 394 Gene3D G3DSA:1.10.3720.10 175 388 6.4E-21 T 31-10-2018 IPR035906 MetI-like superfamily TK2057 5adca5d215dcc4d95e1b9c2885d7faa1 394 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 203 378 1.1E-13 T 31-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TK0948 eb5e23184e7c9ec80503d30076c0bde1 339 SUPERFAMILY SSF55821 9 209 1.28E-69 T 31-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily TK0948 eb5e23184e7c9ec80503d30076c0bde1 339 PIRSF PIRSF004930 2 339 1.9E-132 T 31-10-2018 IPR010923 tRNA threonylcarbamoyladenosine biosynthesis protein SUA5 TK0948 eb5e23184e7c9ec80503d30076c0bde1 339 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 12 207 1.6E-68 T 31-10-2018 IPR006070 YrdC-like domain GO:0003725 TK0948 eb5e23184e7c9ec80503d30076c0bde1 339 Gene3D G3DSA:3.40.50.11030 215 339 3.6E-38 T 31-10-2018 IPR038385 Threonylcarbamoyl-AMP synthase, C-terminal domain superfamily TK0948 eb5e23184e7c9ec80503d30076c0bde1 339 Pfam PF01300 Telomere recombination 22 196 2.5E-61 T 31-10-2018 IPR006070 YrdC-like domain GO:0003725 TK0948 eb5e23184e7c9ec80503d30076c0bde1 339 Pfam PF03481 Putative GTP-binding controlling metal-binding 199 333 2.6E-28 T 31-10-2018 IPR005145 Putative GTP-binding controlling metal-binding domain TK0948 eb5e23184e7c9ec80503d30076c0bde1 339 Gene3D G3DSA:3.90.870.10 3 211 1.5E-86 T 31-10-2018 TK1283 46006342cab8672a8d647829fb009653 215 Gene3D G3DSA:3.40.50.620 1 201 3.9E-64 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TK1283 46006342cab8672a8d647829fb009653 215 Pfam PF00733 Asparagine synthase 9 69 3.0E-6 T 31-10-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 TK1283 46006342cab8672a8d647829fb009653 215 SUPERFAMILY SSF52402 1 147 1.43E-24 T 31-10-2018 TK1179 3ae973045948fe427fe5d001053aab1b 183 Gene3D G3DSA:2.40.320.10 1 180 6.1E-56 T 31-10-2018 TK1179 3ae973045948fe427fe5d001053aab1b 183 Pfam PF01928 CYTH domain 2 169 7.8E-37 T 31-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 TK1179 3ae973045948fe427fe5d001053aab1b 183 TIGRFAM TIGR00318 cyaB: putative adenylyl cyclase CyaB 2 173 6.8E-44 T 31-10-2018 IPR008173 Adenylyl cyclase CyaB KEGG: 00230+4.6.1.1 TK1179 3ae973045948fe427fe5d001053aab1b 183 SUPERFAMILY SSF55154 2 177 2.13E-37 T 31-10-2018 IPR033469 CYTH-like domain superfamily Reactome: R-HSA-196819 TK1179 3ae973045948fe427fe5d001053aab1b 183 ProDom PD009560 CYCLASE ADENYLATE CYCLASE ADENYLYL CYAB LYASE CLASS CYAB-TYPE THERMOPHILIC MJ0240 1 152 7.0E-83 T 31-10-2018 TK1179 3ae973045948fe427fe5d001053aab1b 183 SMART SM01118 1 175 4.4E-24 T 31-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 TK2000 74a466a82069ddf3b67c9c49fdbdb2e0 372 Gene3D G3DSA:1.10.10.2140 320 372 4.0E-27 T 31-10-2018 TK2000 74a466a82069ddf3b67c9c49fdbdb2e0 372 Pfam PF01924 Hydrogenase formation hypA family 13 369 1.4E-138 T 31-10-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 TK2000 74a466a82069ddf3b67c9c49fdbdb2e0 372 Gene3D G3DSA:3.40.50.11750 17 264 9.0E-117 T 31-10-2018 TK2000 74a466a82069ddf3b67c9c49fdbdb2e0 372 PIRSF PIRSF005622 3 372 1.5E-149 T 31-10-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 TK2000 74a466a82069ddf3b67c9c49fdbdb2e0 372 Gene3D G3DSA:3.40.50.11740 63 304 9.0E-117 T 31-10-2018 TK2000 74a466a82069ddf3b67c9c49fdbdb2e0 372 TIGRFAM TIGR00075 hypD: hydrogenase expression/formation protein HypD 6 369 2.6E-141 T 31-10-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 TK1864 76e5782117e755d5f186e88ff6f0f06e 383 Pfam PF12849 PBP superfamily domain 42 352 6.4E-56 T 31-10-2018 IPR024370 PBP domain TK1864 76e5782117e755d5f186e88ff6f0f06e 383 PIRSF PIRSF002756 4 383 1.1E-108 T 31-10-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 TK1864 76e5782117e755d5f186e88ff6f0f06e 383 TIGRFAM TIGR00975 3a0107s03: phosphate ABC transporter, phosphate-binding protein PstS 52 381 2.3E-122 T 31-10-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 TK1864 76e5782117e755d5f186e88ff6f0f06e 383 Gene3D G3DSA:3.40.190.10 132 318 7.7E-102 T 31-10-2018 TK1864 76e5782117e755d5f186e88ff6f0f06e 383 SUPERFAMILY SSF53850 51 381 1.55E-86 T 31-10-2018 TK1864 76e5782117e755d5f186e88ff6f0f06e 383 Gene3D G3DSA:3.40.190.10 56 370 7.7E-102 T 31-10-2018 TK1925 80efda93c0bf351cc2a0048d60dada92 240 Pfam PF10086 Putative membrane peptidase family (DUF2324) 135 201 1.3E-7 T 31-10-2018 IPR011397 Uncharacterised conserved protein UCP033101 TK1925 80efda93c0bf351cc2a0048d60dada92 240 Pfam PF10086 Putative membrane peptidase family (DUF2324) 24 127 1.3E-5 T 31-10-2018 IPR011397 Uncharacterised conserved protein UCP033101 TK0186 71d330589c4fd5a9e32726b669a77b20 417 Pfam PF00155 Aminotransferase class I and II 68 405 1.4E-38 T 31-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 TK0186 71d330589c4fd5a9e32726b669a77b20 417 SUPERFAMILY SSF53383 15 411 1.1E-121 T 31-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TK0186 71d330589c4fd5a9e32726b669a77b20 417 Gene3D G3DSA:3.90.1150.10 34 409 2.0E-164 T 31-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TK0186 71d330589c4fd5a9e32726b669a77b20 417 Gene3D G3DSA:3.40.640.10 79 304 2.0E-164 T 31-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TK1086 524824112bcd66395a365a93d6d828a8 236 SUPERFAMILY SSF46785 155 198 3.75E-5 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TK1086 524824112bcd66395a365a93d6d828a8 236 SMART SM00418 5 86 1.5E-10 T 31-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TK1086 524824112bcd66395a365a93d6d828a8 236 Pfam PF12840 Helix-turn-helix domain 5 58 1.5E-8 T 31-10-2018 TK1086 524824112bcd66395a365a93d6d828a8 236 SUPERFAMILY SSF46785 4 152 3.89E-15 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TK1086 524824112bcd66395a365a93d6d828a8 236 Gene3D G3DSA:1.10.10.10 164 232 7.8E-37 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TK1086 524824112bcd66395a365a93d6d828a8 236 Gene3D G3DSA:1.10.10.10 2 77 1.8E-20 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TK2011 f3487e2a79947f5ebaff6fb789546c6c 51 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 2 49 2.5E-5 T 31-10-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis TK2011 f3487e2a79947f5ebaff6fb789546c6c 51 SUPERFAMILY SSF53146 2 50 8.89E-7 T 31-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily TK1045 56d421d8bf040eb69b85f49a33c9b6ba 171 ProDom PD007457 TRANSFERASE ADENOSYLTRANSFERASE COBALAMIN ATP:COBIALAMIN ADENOSYLTRANSFERASE PDUO TYPE RELATED ACIDURIA YVQK 20 165 4.0E-72 T 31-10-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 TK1045 56d421d8bf040eb69b85f49a33c9b6ba 171 Pfam PF01923 Cobalamin adenosyltransferase 3 159 4.3E-51 T 31-10-2018 IPR016030 Cobalamin adenosyltransferase-like KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 TK1045 56d421d8bf040eb69b85f49a33c9b6ba 171 Gene3D G3DSA:1.20.1200.10 25 171 2.2E-51 T 31-10-2018 IPR036451 Cobalamin adenosyltransferase-like superfamily KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 TK1045 56d421d8bf040eb69b85f49a33c9b6ba 171 SUPERFAMILY SSF89028 1 165 1.55E-52 T 31-10-2018 IPR036451 Cobalamin adenosyltransferase-like superfamily KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 TK1045 56d421d8bf040eb69b85f49a33c9b6ba 171 TIGRFAM TIGR00636 PduO_Nterm: ATP:cob(I)alamin adenosyltransferase 4 169 7.1E-61 T 31-10-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 TK0185 d647d5b08958d56b148142660fd27ec2 322 SUPERFAMILY SSF100950 4 311 2.09E-100 T 31-10-2018 IPR037171 NagB/RpiA transferase-like TK0185 d647d5b08958d56b148142660fd27ec2 322 TIGRFAM TIGR00524 eIF-2B_rel: eIF-2B alpha/beta/delta-related uncharacterized proteins 5 299 5.8E-99 T 31-10-2018 IPR011559 Initiation factor 2B alpha/beta/delta GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 TK0185 d647d5b08958d56b148142660fd27ec2 322 Gene3D G3DSA:3.40.50.10470 115 310 5.8E-85 T 31-10-2018 TK0185 d647d5b08958d56b148142660fd27ec2 322 Gene3D G3DSA:1.20.120.420 1 114 2.0E-49 T 31-10-2018 IPR027363 Methylthioribose-1-phosphate isomerase, N-terminal KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 TK0185 d647d5b08958d56b148142660fd27ec2 322 Pfam PF01008 Initiation factor 2 subunit family 18 299 5.1E-93 T 31-10-2018 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 TK0185 d647d5b08958d56b148142660fd27ec2 322 TIGRFAM TIGR00511 ribulose_e2b2: ribose-1,5-bisphosphate isomerase, e2b2 family 6 312 1.1E-149 T 31-10-2018 IPR005250 Ribose-1,5-bisphosphate isomerase, e2b2 family MetaCyc: PWY-5532 TK1155 0583adb74e097d81b34e09dd8eccf74c 164 Pfam PF00011 Hsp20/alpha crystallin family 60 161 6.0E-20 T 31-10-2018 IPR002068 Alpha crystallin/Hsp20 domain TK1155 0583adb74e097d81b34e09dd8eccf74c 164 SUPERFAMILY SSF49764 44 161 4.71E-33 T 31-10-2018 IPR008978 HSP20-like chaperone TK1155 0583adb74e097d81b34e09dd8eccf74c 164 Gene3D G3DSA:2.60.40.790 4 162 4.7E-33 T 31-10-2018 IPR008978 HSP20-like chaperone TK1264 6dc8813282976b43a231f6da58b83756 635 Gene3D G3DSA:1.10.8.60 319 411 3.7E-44 T 31-10-2018 TK1264 6dc8813282976b43a231f6da58b83756 635 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 438 454 3.7E-29 T 31-10-2018 TK1264 6dc8813282976b43a231f6da58b83756 635 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 515 534 3.7E-29 T 31-10-2018 TK1264 6dc8813282976b43a231f6da58b83756 635 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 65 84 3.7E-29 T 31-10-2018 TK1264 6dc8813282976b43a231f6da58b83756 635 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 545 564 3.7E-29 T 31-10-2018 TK1264 6dc8813282976b43a231f6da58b83756 635 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 568 586 3.7E-29 T 31-10-2018 TK1264 6dc8813282976b43a231f6da58b83756 635 TIGRFAM TIGR00764 lon_rel: putative ATP-dependent protease 22 627 0.0 T 31-10-2018 IPR004663 Lon protease, archaeal GO:0004176|GO:0005524|GO:0030163 TK1264 6dc8813282976b43a231f6da58b83756 635 Pfam PF01078 Magnesium chelatase, subunit ChlI 39 91 1.9E-9 T 31-10-2018 IPR000523 Magnesium chelatase ChlI domain TK1264 6dc8813282976b43a231f6da58b83756 635 SUPERFAMILY SSF52540 34 412 9.27E-38 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK1264 6dc8813282976b43a231f6da58b83756 635 Gene3D G3DSA:3.40.50.300 162 318 2.0E-43 T 31-10-2018 TK1264 6dc8813282976b43a231f6da58b83756 635 Gene3D G3DSA:3.40.50.300 18 128 2.6E-31 T 31-10-2018 TK1264 6dc8813282976b43a231f6da58b83756 635 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 433 613 3.2E-37 T 31-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 TK1264 6dc8813282976b43a231f6da58b83756 635 SUPERFAMILY SSF54211 438 611 5.31E-45 T 31-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TK1264 6dc8813282976b43a231f6da58b83756 635 Gene3D G3DSA:3.30.230.10 430 634 2.5E-79 T 31-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TK1264 6dc8813282976b43a231f6da58b83756 635 SMART SM00382 57 316 1.7E-5 T 31-10-2018 IPR003593 AAA+ ATPase domain TK1264 6dc8813282976b43a231f6da58b83756 635 Pfam PF13654 AAA domain 181 408 1.1E-22 T 31-10-2018 TK1239 56b8786ee92f63947d18921a011e0cc8 415 SUPERFAMILY SSF55315 272 414 7.06E-42 T 31-10-2018 IPR029064 50S ribosomal protein L30e-like TK1239 56b8786ee92f63947d18921a011e0cc8 415 Pfam PF03464 eRF1 domain 2 140 272 6.4E-50 T 31-10-2018 IPR005141 eRF1 domain 2 TK1239 56b8786ee92f63947d18921a011e0cc8 415 SMART SM01194 1 135 4.5E-34 T 31-10-2018 IPR005140 eRF1 domain 1/Pelota-like TK1239 56b8786ee92f63947d18921a011e0cc8 415 Hamap MF_00424 Peptide chain release factor subunit 1 [prf1]. 18 415 45.768 T 31-10-2018 IPR020918 Peptide chain release factor aRF1 GO:0003747|GO:0005737|GO:0006415 TK1239 56b8786ee92f63947d18921a011e0cc8 415 Pfam PF03465 eRF1 domain 3 276 414 8.6E-36 T 31-10-2018 IPR005142 eRF1 domain 3 TK1239 56b8786ee92f63947d18921a011e0cc8 415 TIGRFAM TIGR03676 aRF1/eRF1: peptide chain release factor 1, archaeal and eukaryotic forms 7 414 6.8E-184 T 31-10-2018 IPR004403 Peptide chain release factor eRF1/aRF1 GO:0003747|GO:0005737|GO:0006415 Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1239 56b8786ee92f63947d18921a011e0cc8 415 SUPERFAMILY SSF55481 3 135 3.53E-49 T 31-10-2018 IPR024049 Peptide Chain Release Factor eRF1/aRF1, N-terminal Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1239 56b8786ee92f63947d18921a011e0cc8 415 Gene3D G3DSA:3.30.960.10 1 130 7.6E-55 T 31-10-2018 IPR024049 Peptide Chain Release Factor eRF1/aRF1, N-terminal Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1239 56b8786ee92f63947d18921a011e0cc8 415 SUPERFAMILY SSF53137 138 271 6.54E-44 T 31-10-2018 TK1239 56b8786ee92f63947d18921a011e0cc8 415 Pfam PF03463 eRF1 domain 1 17 133 8.5E-10 T 31-10-2018 IPR005140 eRF1 domain 1/Pelota-like TK1239 56b8786ee92f63947d18921a011e0cc8 415 Gene3D G3DSA:3.30.420.60 131 271 4.6E-54 T 31-10-2018 TK1239 56b8786ee92f63947d18921a011e0cc8 415 Gene3D G3DSA:3.30.1330.30 274 415 1.1E-44 T 31-10-2018 IPR029064 50S ribosomal protein L30e-like TK0707 3f9a3a7a6922f2cdb5fe95dc8a71435d 315 Gene3D G3DSA:1.10.3470.10 2 312 2.5E-92 T 31-10-2018 IPR037294 ABC transporter, BtuC-like TK0707 3f9a3a7a6922f2cdb5fe95dc8a71435d 315 Pfam PF01032 FecCD transport family 12 309 7.2E-82 T 31-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 TK0707 3f9a3a7a6922f2cdb5fe95dc8a71435d 315 SUPERFAMILY SSF81345 7 309 4.97E-74 T 31-10-2018 IPR037294 ABC transporter, BtuC-like TK2148 7c74a9339fdaa40569fa4496a2eae490 484 SUPERFAMILY SSF50998 22 225 1.1E-10 T 31-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily TK2148 7c74a9339fdaa40569fa4496a2eae490 484 Gene3D G3DSA:2.130.10.10 5 252 2.5E-5 T 31-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 TK2148 7c74a9339fdaa40569fa4496a2eae490 484 PIRSF PIRSF016666 1 484 1.9E-265 T 31-10-2018 IPR016675 Uncharacterised conserved protein UCP016666 TK2148 7c74a9339fdaa40569fa4496a2eae490 484 Pfam PF09910 Uncharacterized protein conserved in archaea (DUF2139) 31 362 8.7E-155 T 31-10-2018 IPR016675 Uncharacterised conserved protein UCP016666 TK1380 b1b8dae29e8d64965df55fea6c6faa53 451 PIRSF PIRSF006815 3 446 1.1E-160 T 31-10-2018 IPR023010 Probable glycine dehydrogenase (decarboxylating) subunit 1 GO:0004375|GO:0009116 KEGG: 00260+1.4.4.2 TK1380 b1b8dae29e8d64965df55fea6c6faa53 451 Gene3D G3DSA:3.40.640.10 81 349 1.4E-150 T 31-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TK1380 b1b8dae29e8d64965df55fea6c6faa53 451 Hamap MF_00712 Probable glycine dehydrogenase (decarboxylating) subunit 1 [gcvPA]. 3 445 47.602 T 31-10-2018 IPR023010 Probable glycine dehydrogenase (decarboxylating) subunit 1 GO:0004375|GO:0009116 KEGG: 00260+1.4.4.2 TK1380 b1b8dae29e8d64965df55fea6c6faa53 451 Pfam PF02347 Glycine cleavage system P-protein 5 441 5.1E-123 T 31-10-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 TK1380 b1b8dae29e8d64965df55fea6c6faa53 451 Gene3D G3DSA:3.90.1150.10 70 442 1.4E-150 T 31-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TK1380 b1b8dae29e8d64965df55fea6c6faa53 451 SUPERFAMILY SSF53383 3 445 8.11E-104 T 31-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TK2254 b783b14b8af358109bab203102c4439b 298 Pfam PF00953 Glycosyl transferase family 4 67 211 8.7E-33 T 31-10-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 TK1686 8c76452d02036b25095863f7bc56bfbf 261 Gene3D G3DSA:3.40.50.12640 1 261 2.4E-122 T 31-10-2018 IPR038138 Phosphopantoate/pantothenate synthetase superfamily TK1686 8c76452d02036b25095863f7bc56bfbf 261 PIRSF PIRSF004853 1 254 3.7E-115 T 31-10-2018 IPR002855 Phosphopantoate/pantothenate synthetase TK1686 8c76452d02036b25095863f7bc56bfbf 261 ProDom PD016827 ARCHAEA ST0532 APE1937 VNG0250C MM2281 PAE3406 AF0927 UNCHARACTERIZED C3_0043 MJ0209 67 252 2.0E-101 T 31-10-2018 IPR002855 Phosphopantoate/pantothenate synthetase TK1686 8c76452d02036b25095863f7bc56bfbf 261 Pfam PF02006 Phosphopantothenate/pantothenate synthetase 67 241 2.6E-75 T 31-10-2018 IPR002855 Phosphopantoate/pantothenate synthetase TK0676 fced0b627bbeb3fae368c3666441012c 554 Pfam PF00005 ABC transporter 341 479 2.5E-28 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TK0676 fced0b627bbeb3fae368c3666441012c 554 SUPERFAMILY SSF90123 7 315 2.62E-48 T 31-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TK0676 fced0b627bbeb3fae368c3666441012c 554 ProSitePatterns PS00211 ABC transporters family signature. 451 465 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TK0676 fced0b627bbeb3fae368c3666441012c 554 SUPERFAMILY SSF52540 320 547 2.32E-59 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK0676 fced0b627bbeb3fae368c3666441012c 554 Pfam PF00664 ABC transporter transmembrane region 19 278 1.8E-25 T 31-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 TK0676 fced0b627bbeb3fae368c3666441012c 554 Gene3D G3DSA:3.40.50.300 315 553 1.4E-67 T 31-10-2018 TK0676 fced0b627bbeb3fae368c3666441012c 554 SMART SM00382 350 538 6.8E-17 T 31-10-2018 IPR003593 AAA+ ATPase domain TK0676 fced0b627bbeb3fae368c3666441012c 554 Gene3D G3DSA:1.20.1560.10 1 313 1.2E-42 T 31-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TK0474 e486244ed15066d2ec813113341d5c26 244 PIRSF PIRSF036979 35 236 9.4E-16 T 31-10-2018 IPR006035 Ureohydrolase GO:0046872 TK0474 e486244ed15066d2ec813113341d5c26 244 Pfam PF00491 Arginase family 56 230 4.4E-18 T 31-10-2018 IPR006035 Ureohydrolase GO:0046872 TK0474 e486244ed15066d2ec813113341d5c26 244 Gene3D G3DSA:3.40.800.10 35 243 2.0E-19 T 31-10-2018 TK0474 e486244ed15066d2ec813113341d5c26 244 SUPERFAMILY SSF52768 56 235 2.7E-26 T 31-10-2018 IPR023696 Ureohydrolase domain superfamily TK2244 05b312ede7b58dc3ee2f85738fe47eb0 194 Gene3D G3DSA:3.40.920.10 1 194 3.6E-35 T 31-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 TK2244 05b312ede7b58dc3ee2f85738fe47eb0 194 SUPERFAMILY SSF53323 2 193 1.12E-27 T 31-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 TK2244 05b312ede7b58dc3ee2f85738fe47eb0 194 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 11 190 4.2E-35 T 31-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 TK1522 d2827fb7fb3dc0afc9dcaf6c31b18af1 201 Hamap MF_01337_A 50S ribosomal protein L18 [rplR]. 5 192 44.978 T 31-10-2018 IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0008097 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1522 d2827fb7fb3dc0afc9dcaf6c31b18af1 201 Pfam PF17144 Ribosomal large subunit proteins 60S L5, and 50S L18 98 134 8.9E-9 T 31-10-2018 IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0008097 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1522 d2827fb7fb3dc0afc9dcaf6c31b18af1 201 Pfam PF17144 Ribosomal large subunit proteins 60S L5, and 50S L18 6 94 3.3E-15 T 31-10-2018 IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0008097 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1522 d2827fb7fb3dc0afc9dcaf6c31b18af1 201 Pfam PF14204 Ribosomal L18 C-terminal region 143 194 1.0E-11 T 31-10-2018 IPR025607 Ribosomal protein L5 eukaryotic/L18 archaeal, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1522 d2827fb7fb3dc0afc9dcaf6c31b18af1 201 Gene3D G3DSA:3.30.420.100 1 197 2.1E-72 T 31-10-2018 TK1522 d2827fb7fb3dc0afc9dcaf6c31b18af1 201 PRINTS PR00058 Ribosomal protein L5 signature 123 142 6.7E-10 T 31-10-2018 IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0008097 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1522 d2827fb7fb3dc0afc9dcaf6c31b18af1 201 PRINTS PR00058 Ribosomal protein L5 signature 1 12 6.7E-10 T 31-10-2018 IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0008097 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1522 d2827fb7fb3dc0afc9dcaf6c31b18af1 201 PRINTS PR00058 Ribosomal protein L5 signature 103 122 6.7E-10 T 31-10-2018 IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0008097 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1522 d2827fb7fb3dc0afc9dcaf6c31b18af1 201 SUPERFAMILY SSF53137 2 195 8.07E-64 T 31-10-2018 TK0343 d6e027fcdeaac44890e3373e9e2e2577 152 Pfam PF01850 PIN domain 5 131 2.3E-13 T 31-10-2018 IPR002716 PIN domain TK0343 d6e027fcdeaac44890e3373e9e2e2577 152 Gene3D G3DSA:3.40.50.1010 4 150 2.5E-6 T 31-10-2018 TK0343 d6e027fcdeaac44890e3373e9e2e2577 152 SUPERFAMILY SSF88723 1 134 1.23E-15 T 31-10-2018 IPR029060 PIN-like domain superfamily TK1822 cdf5817381679817ab728d4e35bae66e 424 Pfam PF13635 Domain of unknown function (DUF4143) 241 361 4.5E-7 T 31-10-2018 IPR025420 Domain of unknown function DUF4143 TK1822 cdf5817381679817ab728d4e35bae66e 424 SUPERFAMILY SSF52540 29 223 1.13E-19 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK1822 cdf5817381679817ab728d4e35bae66e 424 Pfam PF13173 AAA domain 35 166 7.2E-37 T 31-10-2018 TK0554 217f13153a7b7b01badbedd093469401 198 Gene3D G3DSA:3.40.1280.10 1 198 1.4E-72 T 31-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal TK0554 217f13153a7b7b01badbedd093469401 198 Hamap MF_00587 tRNA (pseudouridine(54)-N(1))-methyltransferase [trmY]. 1 197 36.625 T 31-10-2018 IPR007158 tRNA (pseudouridine(54)-N(1))-methyltransferase, TrmY GO:0008175 TK0554 217f13153a7b7b01badbedd093469401 198 Pfam PF04013 Putative SAM-dependent RNA methyltransferase 1 196 1.4E-53 T 31-10-2018 IPR007158 tRNA (pseudouridine(54)-N(1))-methyltransferase, TrmY GO:0008175 TK0554 217f13153a7b7b01badbedd093469401 198 SUPERFAMILY SSF75217 1 196 4.97E-68 T 31-10-2018 IPR029028 Alpha/beta knot methyltransferases TK0279 7da30346783932ff9963dc8ebe531a8e 53 Gene3D G3DSA:2.20.28.160 1 53 9.0E-25 T 31-10-2018 TK0279 7da30346783932ff9963dc8ebe531a8e 53 TIGRFAM TIGR01206 lysW: lysine biosynthesis protein LysW 2 53 6.7E-26 T 31-10-2018 IPR005906 Lysine biosynthesis protein LysW TK1674 dd73ac0479b12d577e6af5369f88b0ef 173 Gene3D G3DSA:2.30.110.10 1 161 1.5E-46 T 31-10-2018 IPR012349 FMN-binding split barrel GO:0048037 TK1674 dd73ac0479b12d577e6af5369f88b0ef 173 Pfam PF01613 Flavin reductase like domain 6 137 6.6E-24 T 31-10-2018 IPR002563 Flavin reductase like domain GO:0010181 TK1674 dd73ac0479b12d577e6af5369f88b0ef 173 SMART SM00903 3 146 8.3E-17 T 31-10-2018 IPR002563 Flavin reductase like domain GO:0010181 TK1674 dd73ac0479b12d577e6af5369f88b0ef 173 SUPERFAMILY SSF50475 1 160 4.32E-39 T 31-10-2018 TK1829 cad0666d6e5b76dd4238398efd934dd3 445 Gene3D G3DSA:1.20.1250.20 3 390 7.4E-65 T 31-10-2018 TK1829 cad0666d6e5b76dd4238398efd934dd3 445 Pfam PF07690 Major Facilitator Superfamily 14 369 7.6E-53 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TK1829 cad0666d6e5b76dd4238398efd934dd3 445 SUPERFAMILY SSF103473 5 421 1.57E-68 T 31-10-2018 IPR036259 MFS transporter superfamily TK1391 379f040410d83ff15ab4acf021e8e89e 114 Gene3D G3DSA:3.10.530.10 46 112 6.3E-16 T 31-10-2018 IPR036593 CPE0013-like superfamily TK1391 379f040410d83ff15ab4acf021e8e89e 114 Pfam PF07892 Protein of unknown function (DUF1667) 34 112 1.2E-26 T 31-10-2018 IPR012460 Protein of unknown function DUF1667 TK1391 379f040410d83ff15ab4acf021e8e89e 114 SUPERFAMILY SSF53706 2 51 2.43E-7 T 31-10-2018 TK1391 379f040410d83ff15ab4acf021e8e89e 114 SUPERFAMILY SSF160148 46 113 6.02E-19 T 31-10-2018 IPR036593 CPE0013-like superfamily TK2018 d540e2c9706f2c9282750f9ff278cd7d 377 SUPERFAMILY SSF53807 38 353 2.04E-56 T 31-10-2018 TK2018 d540e2c9706f2c9282750f9ff278cd7d 377 Gene3D G3DSA:3.40.50.1980 27 176 2.5E-51 T 31-10-2018 TK2018 d540e2c9706f2c9282750f9ff278cd7d 377 Gene3D G3DSA:3.40.50.1980 178 373 4.1E-79 T 31-10-2018 TK2018 d540e2c9706f2c9282750f9ff278cd7d 377 Pfam PF01497 Periplasmic binding protein 99 298 1.5E-24 T 31-10-2018 IPR002491 ABC transporter periplasmic binding domain TK1166 c7efdb0ad4988dd9da1edaa808ce6b1f 133 SUPERFAMILY SSF69065 10 132 9.42E-58 T 31-10-2018 IPR036389 Ribonuclease III, endonuclease domain superfamily GO:0004525|GO:0006396 TK1166 c7efdb0ad4988dd9da1edaa808ce6b1f 133 Pfam PF11469 Ribonuclease III 13 130 6.4E-63 T 31-10-2018 IPR021568 Ribonuclease III, archaeal TK1166 c7efdb0ad4988dd9da1edaa808ce6b1f 133 Gene3D G3DSA:1.10.1520.20 5 132 2.3E-46 T 31-10-2018 IPR038133 Ribonuclease III superfamily, archaeal TK1910 0d7aebb12e8df801b6efd89d2dee75c0 237 SUPERFAMILY SSF52540 8 233 1.76E-42 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK1910 0d7aebb12e8df801b6efd89d2dee75c0 237 Gene3D G3DSA:3.40.50.300 7 235 6.1E-59 T 31-10-2018 TK1910 0d7aebb12e8df801b6efd89d2dee75c0 237 Pfam PF06745 KaiC 13 234 1.4E-48 T 31-10-2018 IPR014774 KaiC-like domain TK1109 947ae6b4d4538f46065108deac6f1305 465 Gene3D G3DSA:2.60.120.10 348 451 1.5E-18 T 31-10-2018 IPR014710 RmlC-like jelly roll fold TK1109 947ae6b4d4538f46065108deac6f1305 465 Pfam PF00483 Nucleotidyl transferase 2 276 2.3E-58 T 31-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 TK1109 947ae6b4d4538f46065108deac6f1305 465 Pfam PF01050 Mannose-6-phosphate isomerase 310 460 1.7E-65 T 31-10-2018 IPR001538 Mannose-6-phosphate isomerase, type II, C-terminal GO:0005976|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882 TK1109 947ae6b4d4538f46065108deac6f1305 465 TIGRFAM TIGR01479 GMP_PMI: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase 2 463 2.8E-160 T 31-10-2018 IPR006375 Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase GO:0000271|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882 TK1109 947ae6b4d4538f46065108deac6f1305 465 SUPERFAMILY SSF53448 1 271 7.51E-66 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TK1109 947ae6b4d4538f46065108deac6f1305 465 SUPERFAMILY SSF51182 191 464 3.2E-66 T 31-10-2018 IPR011051 RmlC-like cupin domain superfamily TK1109 947ae6b4d4538f46065108deac6f1305 465 Gene3D G3DSA:3.90.550.10 1 345 3.2E-112 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TK0734 77be421d281df8e4e6e3c58c0eff752f 160 Pfam PF01850 PIN domain 6 148 1.4E-26 T 31-10-2018 IPR002716 PIN domain TK0734 77be421d281df8e4e6e3c58c0eff752f 160 SMART SM00670 4 144 1.3E-12 T 31-10-2018 IPR002716 PIN domain TK0734 77be421d281df8e4e6e3c58c0eff752f 160 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 6 152 11.06 T 31-10-2018 IPR022907 VapC family GO:0004540 TK0734 77be421d281df8e4e6e3c58c0eff752f 160 Gene3D G3DSA:3.40.50.1010 5 156 1.9E-18 T 31-10-2018 TK0734 77be421d281df8e4e6e3c58c0eff752f 160 SUPERFAMILY SSF88723 5 147 3.08E-23 T 31-10-2018 IPR029060 PIN-like domain superfamily TK0224 cb884b44e5327fd3486e91586a1f42d7 207 Pfam PF08241 Methyltransferase domain 44 134 4.4E-20 T 31-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 TK0224 cb884b44e5327fd3486e91586a1f42d7 207 Gene3D G3DSA:3.40.50.150 23 205 1.0E-39 T 31-10-2018 TK0224 cb884b44e5327fd3486e91586a1f42d7 207 SUPERFAMILY SSF53335 6 183 2.46E-35 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TK1707 d9fb0d994b70cb815d22fc591d74b68b 73 SUPERFAMILY SSF46785 7 71 2.15E-5 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TK1261 e3f6849dcb0b864d04624979c5134ec3 128 SUPERFAMILY SSF46785 38 125 4.41E-23 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TK1261 e3f6849dcb0b864d04624979c5134ec3 128 Pfam PF01022 Bacterial regulatory protein, arsR family 51 96 2.2E-10 T 31-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TK1261 e3f6849dcb0b864d04624979c5134ec3 128 SMART SM00418 44 122 5.2E-26 T 31-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TK1261 e3f6849dcb0b864d04624979c5134ec3 128 Gene3D G3DSA:1.10.10.10 2 123 5.1E-27 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TK1261 e3f6849dcb0b864d04624979c5134ec3 128 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 78 93 7.5E-15 T 31-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TK1261 e3f6849dcb0b864d04624979c5134ec3 128 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 46 61 7.5E-15 T 31-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TK1261 e3f6849dcb0b864d04624979c5134ec3 128 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 65 76 7.5E-15 T 31-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TK1261 e3f6849dcb0b864d04624979c5134ec3 128 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 93 108 7.5E-15 T 31-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TK0354 8019b9dd12e984e2b06b3989be686bc5 156 Hamap MF_01224_A Cyclic pyranopterin monophosphate synthase [moaC]. 9 154 39.3 T 31-10-2018 IPR023047 Probable cyclic pyranopterin monophosphate synthase accessory protein, archaea KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823 TK0354 8019b9dd12e984e2b06b3989be686bc5 156 Gene3D G3DSA:3.30.70.640 1 156 1.0E-67 T 31-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TK0354 8019b9dd12e984e2b06b3989be686bc5 156 Pfam PF01967 MoaC family 14 154 6.8E-52 T 31-10-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TK0354 8019b9dd12e984e2b06b3989be686bc5 156 TIGRFAM TIGR00581 moaC: molybdenum cofactor biosynthesis protein C 4 138 5.2E-54 T 31-10-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TK0354 8019b9dd12e984e2b06b3989be686bc5 156 SUPERFAMILY SSF55040 12 155 1.2E-51 T 31-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TK1099 89cf9412ee8ea158bc7c4a8db563aa54 65 Pfam PF01667 Ribosomal protein S27 11 64 1.7E-26 T 31-10-2018 IPR000592 Ribosomal protein S27e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1099 89cf9412ee8ea158bc7c4a8db563aa54 65 Hamap MF_00371 30S ribosomal protein S27e [rps27e]. 5 64 22.608 T 31-10-2018 IPR000592 Ribosomal protein S27e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1099 89cf9412ee8ea158bc7c4a8db563aa54 65 SUPERFAMILY SSF57829 11 65 1.04E-19 T 31-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 TK1099 89cf9412ee8ea158bc7c4a8db563aa54 65 Gene3D G3DSA:2.20.25.100 11 65 3.9E-25 T 31-10-2018 IPR023407 Ribosomal protein S27e, zinc-binding domain superfamily TK1099 89cf9412ee8ea158bc7c4a8db563aa54 65 ProSitePatterns PS01168 Ribosomal protein S27e signature. 19 51 - T 31-10-2018 IPR000592 Ribosomal protein S27e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1943 1449e2af83dfb31653be79ff5dc3a991 218 ProDom PD019177 PF1672 MJ0935 ST1363 PH1730 UNCHARACTERIZED ARCHAEAL 1 55 2.0E-25 T 31-10-2018 IPR007368 Protein of unknown function DUF434 TK1943 1449e2af83dfb31653be79ff5dc3a991 218 Pfam PF04256 Protein of unknown function (DUF434) 3 57 5.8E-25 T 31-10-2018 IPR007368 Protein of unknown function DUF434 TK0336 bb62d78b940995cc1126d5463818cc01 255 Gene3D G3DSA:3.20.20.370 1 255 1.3E-111 T 31-10-2018 TK0336 bb62d78b940995cc1126d5463818cc01 255 Pfam PF03746 LamB/YcsF family 3 241 7.0E-105 T 31-10-2018 IPR005501 UPF0271 family, LamB/YcsF/PxpA KEGG: 00480+3.5.2.9|MetaCyc: PWY-4041|MetaCyc: PWY-7942 TK0336 bb62d78b940995cc1126d5463818cc01 255 SUPERFAMILY SSF88713 2 253 1.52E-104 T 31-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 TK0336 bb62d78b940995cc1126d5463818cc01 255 Hamap MF_00691 UPF0271 protein YbgL [ybgL]. 1 245 47.094 T 31-10-2018 IPR005501 UPF0271 family, LamB/YcsF/PxpA KEGG: 00480+3.5.2.9|MetaCyc: PWY-4041|MetaCyc: PWY-7942 TK1540 ee4b6ca7fe7dffeb310b28a285cffdfd 86 ProSitePatterns PS00050 Ribosomal protein L23 signature. 64 79 - T 31-10-2018 IPR001014 Ribosomal protein L23/L25, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1540 ee4b6ca7fe7dffeb310b28a285cffdfd 86 Gene3D G3DSA:3.30.70.330 1 86 2.3E-37 T 31-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily TK1540 ee4b6ca7fe7dffeb310b28a285cffdfd 86 SUPERFAMILY SSF54189 4 78 4.68E-28 T 31-10-2018 IPR012678 Ribosomal protein L23/L15e core domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 TK1540 ee4b6ca7fe7dffeb310b28a285cffdfd 86 TIGRFAM TIGR03636 uL23_arch: ribosomal protein uL23 10 86 1.5E-39 T 31-10-2018 IPR019985 Ribosomal protein L23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1540 ee4b6ca7fe7dffeb310b28a285cffdfd 86 Pfam PF00276 Ribosomal protein L23 5 72 1.3E-19 T 31-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 TK1540 ee4b6ca7fe7dffeb310b28a285cffdfd 86 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 4 82 14.772 T 31-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 TK1540 ee4b6ca7fe7dffeb310b28a285cffdfd 86 Hamap MF_01369_A 50S ribosomal protein L23 [rplW]. 6 86 28.01 T 31-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 TK1901 5b48e4244f4741669160565881f229c2 415 Pfam PF09079 CDC6, C terminal winged helix domain 312 391 7.8E-26 T 31-10-2018 IPR015163 Cdc6, C-terminal Reactome: R-HSA-176187|Reactome: R-HSA-539107|Reactome: R-HSA-68689|Reactome: R-HSA-68827|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962 TK1901 5b48e4244f4741669160565881f229c2 415 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 61 196 8.6E-10 T 31-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TK1901 5b48e4244f4741669160565881f229c2 415 SUPERFAMILY SSF52540 19 291 2.01E-55 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK1901 5b48e4244f4741669160565881f229c2 415 Gene3D G3DSA:1.10.8.60 19 295 9.3E-110 T 31-10-2018 TK1901 5b48e4244f4741669160565881f229c2 415 Gene3D G3DSA:1.10.10.10 304 404 4.1E-32 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TK1901 5b48e4244f4741669160565881f229c2 415 SMART SM01074 312 393 2.7E-35 T 31-10-2018 IPR015163 Cdc6, C-terminal Reactome: R-HSA-176187|Reactome: R-HSA-539107|Reactome: R-HSA-68689|Reactome: R-HSA-68827|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962 TK1901 5b48e4244f4741669160565881f229c2 415 Hamap MF_01407 ORC1-type DNA replication protein. 12 394 34.258 T 31-10-2018 IPR014277 Orc1/Cdc6-type DNA replication protein, archaea TK1901 5b48e4244f4741669160565881f229c2 415 SUPERFAMILY SSF46785 297 402 1.81E-31 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TK1901 5b48e4244f4741669160565881f229c2 415 TIGRFAM TIGR02928 TIGR02928: orc1/cdc6 family replication initiation protein 19 383 3.8E-151 T 31-10-2018 IPR014277 Orc1/Cdc6-type DNA replication protein, archaea TK1901 5b48e4244f4741669160565881f229c2 415 Gene3D G3DSA:3.40.50.300 35 216 9.3E-110 T 31-10-2018 TK1901 5b48e4244f4741669160565881f229c2 415 SMART SM00382 57 218 7.1E-11 T 31-10-2018 IPR003593 AAA+ ATPase domain TK2132 aef738907c0184cd7e8a900ddf0cabb8 184 SUPERFAMILY SSF53639 4 182 1.22E-57 T 31-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily TK2132 aef738907c0184cd7e8a900ddf0cabb8 184 SMART SM01007 6 180 9.0E-61 T 31-10-2018 IPR001303 Class II aldolase/adducin N-terminal TK2132 aef738907c0184cd7e8a900ddf0cabb8 184 Gene3D G3DSA:3.40.225.10 2 184 1.2E-62 T 31-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily TK2132 aef738907c0184cd7e8a900ddf0cabb8 184 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 7 179 2.2E-49 T 31-10-2018 IPR001303 Class II aldolase/adducin N-terminal TK1733 75172bff1405d478f716f573fc782a5f 369 Gene3D G3DSA:3.40.50.2000 1 189 1.6E-24 T 31-10-2018 TK1733 75172bff1405d478f716f573fc782a5f 369 Gene3D G3DSA:3.40.50.2000 190 354 1.9E-39 T 31-10-2018 TK1733 75172bff1405d478f716f573fc782a5f 369 SUPERFAMILY SSF53756 1 365 2.54E-73 T 31-10-2018 TK1733 75172bff1405d478f716f573fc782a5f 369 Pfam PF00534 Glycosyl transferases group 1 177 348 3.5E-39 T 31-10-2018 IPR001296 Glycosyl transferase, family 1 TK1733 75172bff1405d478f716f573fc782a5f 369 Pfam PF13579 Glycosyl transferase 4-like domain 16 174 3.7E-13 T 31-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 TK0143 6b8e8240cea51fc4a7d280e1cda9c376 47 ProSitePatterns PS00028 Zinc finger C2H2 type domain signature. 20 41 - T 31-10-2018 IPR013087 Zinc finger C2H2-type GO:0003676 TK0143 6b8e8240cea51fc4a7d280e1cda9c376 47 Pfam PF00096 Zinc finger, C2H2 type 18 41 8.9E-6 T 31-10-2018 IPR013087 Zinc finger C2H2-type GO:0003676 TK0143 6b8e8240cea51fc4a7d280e1cda9c376 47 Gene3D G3DSA:3.30.160.60 15 43 2.3E-5 T 31-10-2018 TK0143 6b8e8240cea51fc4a7d280e1cda9c376 47 SMART SM00355 18 41 0.0018 T 31-10-2018 IPR013087 Zinc finger C2H2-type GO:0003676 TK0143 6b8e8240cea51fc4a7d280e1cda9c376 47 SUPERFAMILY SSF57667 13 43 6.45E-5 T 31-10-2018 IPR036236 Zinc finger C2H2 superfamily TK1957 2262052f341a22ca7830ecc7d0440dc5 277 Pfam PF01040 UbiA prenyltransferase family 23 256 3.1E-47 T 31-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 TK1957 2262052f341a22ca7830ecc7d0440dc5 277 Hamap MF_01286 Digeranylgeranylglyceryl phosphate synthase. 3 275 23.245 T 31-10-2018 IPR023547 Digeranylgeranylglyceryl phosphate synthase GO:0000287|GO:0005886|GO:0008654|GO:0047295 KEGG: 00564+2.5.1.42|MetaCyc: PWY-6349 TK1957 2262052f341a22ca7830ecc7d0440dc5 277 Gene3D G3DSA:1.10.357.140 9 156 1.9E-18 T 31-10-2018 TK1877 c32b9a46fdbb34e500dfc0f2755646d5 455 Pfam PF01637 ATPase domain predominantly from Archaea 8 203 1.5E-27 T 31-10-2018 IPR011579 ATPase domain GO:0005524 TK1877 c32b9a46fdbb34e500dfc0f2755646d5 455 SUPERFAMILY SSF52980 338 403 1.09E-5 T 31-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 TK1877 c32b9a46fdbb34e500dfc0f2755646d5 455 Gene3D G3DSA:3.40.50.300 2 168 9.5E-33 T 31-10-2018 TK1877 c32b9a46fdbb34e500dfc0f2755646d5 455 SUPERFAMILY SSF52540 6 241 4.14E-39 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK1877 c32b9a46fdbb34e500dfc0f2755646d5 455 SUPERFAMILY SSF46785 242 317 1.85E-8 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TK1877 c32b9a46fdbb34e500dfc0f2755646d5 455 Pfam PF03008 Archaea bacterial proteins of unknown function 309 405 7.5E-31 T 31-10-2018 IPR004256 Domain of unknown function DUF234, DEXX-box ATPase C-terminal TK1335 aa2a9cf8b36130a98b916483ce300c6b 138 Gene3D G3DSA:3.30.1440.10 1 137 1.0E-44 T 31-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1335 aa2a9cf8b36130a98b916483ce300c6b 138 SUPERFAMILY SSF55282 7 137 1.24E-40 T 31-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1335 aa2a9cf8b36130a98b916483ce300c6b 138 Pfam PF01877 RNA binding 7 116 4.4E-18 T 31-10-2018 IPR002739 Uncharacterised protein family UPF0201 TK1335 aa2a9cf8b36130a98b916483ce300c6b 138 Hamap MF_01112 UPF0201 protein . 6 135 25.184 T 31-10-2018 IPR002739 Uncharacterised protein family UPF0201 TK1276 f519a3f5036ab68194d422d207c6ff16 150 Gene3D G3DSA:1.10.10.2700 1 150 3.5E-66 T 31-10-2018 IPR038111 Ribosomal protein S19e domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1276 f519a3f5036ab68194d422d207c6ff16 150 Pfam PF01090 Ribosomal protein S19e 3 138 3.3E-58 T 31-10-2018 IPR001266 Ribosomal protein S19e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1276 f519a3f5036ab68194d422d207c6ff16 150 Hamap MF_01474 30S ribosomal protein S19e [rps19e]. 1 148 37.887 T 31-10-2018 IPR027548 Ribosomal protein S19e, archaeal GO:0003735|GO:0005840|GO:0006412 TK1276 f519a3f5036ab68194d422d207c6ff16 150 ProSitePatterns PS00628 Ribosomal protein S19e signature. 87 106 - T 31-10-2018 IPR018277 Ribosomal protein S19e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1276 f519a3f5036ab68194d422d207c6ff16 150 SUPERFAMILY SSF46785 3 150 3.45E-61 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TK1276 f519a3f5036ab68194d422d207c6ff16 150 SMART SM01413 3 139 3.3E-90 T 31-10-2018 IPR001266 Ribosomal protein S19e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1276 f519a3f5036ab68194d422d207c6ff16 150 ProDom PD003854 RIBOSOMAL 40S RIBONUCLEOPROTEIN S19 S19E 30S MULTIGENE FAMILY S19 SSU 3 115 7.0E-61 T 31-10-2018 IPR001266 Ribosomal protein S19e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK2220 e7ef1f825159fbb41f387c882a9a95d6 438 SMART SM00382 40 168 2.5E-4 T 31-10-2018 IPR003593 AAA+ ATPase domain TK2220 e7ef1f825159fbb41f387c882a9a95d6 438 Gene3D G3DSA:3.40.50.300 13 110 8.3E-7 T 31-10-2018 TK2220 e7ef1f825159fbb41f387c882a9a95d6 438 SUPERFAMILY SSF52540 26 235 4.2E-26 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK2220 e7ef1f825159fbb41f387c882a9a95d6 438 Pfam PF13173 AAA domain 42 175 1.6E-32 T 31-10-2018 TK2220 e7ef1f825159fbb41f387c882a9a95d6 438 Pfam PF13635 Domain of unknown function (DUF4143) 257 373 3.3E-13 T 31-10-2018 IPR025420 Domain of unknown function DUF4143 TK2170 97e2e6dd7b2c46f9a4a3645d7543dfc1 429 Gene3D G3DSA:3.30.2290.10 1 209 4.8E-19 T 31-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal TK2170 97e2e6dd7b2c46f9a4a3645d7543dfc1 429 Pfam PF01523 Putative modulator of DNA gyrase 18 305 7.9E-54 T 31-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 TK2170 97e2e6dd7b2c46f9a4a3645d7543dfc1 429 SUPERFAMILY SSF111283 2 424 5.75E-86 T 31-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 TK0891 5f0f06a88a852be4ff06fff6d5f503cb 387 Pfam PF00534 Glycosyl transferases group 1 192 351 2.6E-41 T 31-10-2018 IPR001296 Glycosyl transferase, family 1 TK0891 5f0f06a88a852be4ff06fff6d5f503cb 387 Pfam PF13439 Glycosyltransferase Family 4 18 185 1.8E-25 T 31-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 TK0891 5f0f06a88a852be4ff06fff6d5f503cb 387 Gene3D G3DSA:3.40.50.2000 181 353 3.9E-88 T 31-10-2018 TK0891 5f0f06a88a852be4ff06fff6d5f503cb 387 SUPERFAMILY SSF53756 5 375 1.54E-95 T 31-10-2018 TK0891 5f0f06a88a852be4ff06fff6d5f503cb 387 Gene3D G3DSA:3.40.50.2000 8 370 3.9E-88 T 31-10-2018 TK0735 8a36109b32a6832db2a74d6db3b10792 270 SUPERFAMILY SSF56281 4 249 1.28E-34 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TK0735 8a36109b32a6832db2a74d6db3b10792 270 SMART SM00849 21 242 1.2E-9 T 31-10-2018 IPR001279 Metallo-beta-lactamase TK0735 8a36109b32a6832db2a74d6db3b10792 270 Pfam PF00753 Metallo-beta-lactamase superfamily 22 154 4.0E-16 T 31-10-2018 IPR001279 Metallo-beta-lactamase TK0735 8a36109b32a6832db2a74d6db3b10792 270 Gene3D G3DSA:3.60.15.10 1 269 2.7E-75 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TK1575 f5e16d51ebfdc3309d7fb9115a465492 257 Gene3D G3DSA:3.30.70.1450 153 235 1.8E-14 T 31-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 TK1575 f5e16d51ebfdc3309d7fb9115a465492 257 Pfam PF02080 TrkA-C domain 156 225 2.5E-11 T 31-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 TK1575 f5e16d51ebfdc3309d7fb9115a465492 257 SUPERFAMILY SSF116726 143 226 2.88E-14 T 31-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 TK0026 fe974fc5d21bbf1923943ff8fcee0355 217 SUPERFAMILY SSF56784 1 215 5.7E-41 T 31-10-2018 IPR036412 HAD-like superfamily TK0026 fe974fc5d21bbf1923943ff8fcee0355 217 Gene3D G3DSA:3.40.50.1000 5 188 4.8E-30 T 31-10-2018 IPR023214 HAD superfamily TK0026 fe974fc5d21bbf1923943ff8fcee0355 217 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 188 6.2E-26 T 31-10-2018 TK0026 fe974fc5d21bbf1923943ff8fcee0355 217 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 98 188 1.7E-7 T 31-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TK0026 fe974fc5d21bbf1923943ff8fcee0355 217 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 67 184 1.2E-8 T 31-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TK0026 fe974fc5d21bbf1923943ff8fcee0355 217 Gene3D G3DSA:1.10.150.240 22 86 4.8E-30 T 31-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 TK1842 9b6a9cab6588bf3ea300f8f7afdc78f9 393 Pfam PF07282 Putative transposase DNA-binding domain 290 356 4.7E-26 T 31-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal TK1842 9b6a9cab6588bf3ea300f8f7afdc78f9 393 SUPERFAMILY SSF75712 273 336 1.44E-11 T 31-10-2018 TK1842 9b6a9cab6588bf3ea300f8f7afdc78f9 393 Pfam PF01385 Probable transposase 168 257 9.5E-7 T 31-10-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 TK1842 9b6a9cab6588bf3ea300f8f7afdc78f9 393 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 238 317 9.7E-26 T 31-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal TK1144 1f8f7991123b6a2dbdc0bf8cf37e0af6 328 Pfam PF00005 ABC transporter 21 163 4.9E-35 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TK1144 1f8f7991123b6a2dbdc0bf8cf37e0af6 328 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TK1144 1f8f7991123b6a2dbdc0bf8cf37e0af6 328 Gene3D G3DSA:3.40.50.300 1 232 3.9E-75 T 31-10-2018 TK1144 1f8f7991123b6a2dbdc0bf8cf37e0af6 328 SUPERFAMILY SSF52540 5 224 4.49E-70 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK1144 1f8f7991123b6a2dbdc0bf8cf37e0af6 328 Pfam PF13732 Domain of unknown function (DUF4162) 218 303 3.8E-7 T 31-10-2018 IPR025302 Domain of unknown function DUF4162 TK1144 1f8f7991123b6a2dbdc0bf8cf37e0af6 328 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 12 305 4.0E-123 T 31-10-2018 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 TK1144 1f8f7991123b6a2dbdc0bf8cf37e0af6 328 SMART SM00382 29 213 1.7E-9 T 31-10-2018 IPR003593 AAA+ ATPase domain TK1954 e063c36db3cddbe454f5aa6e740ace47 183 Pfam PF01926 50S ribosome-binding GTPase 2 129 7.4E-18 T 31-10-2018 IPR006073 GTP binding domain GO:0005525 TK1954 e063c36db3cddbe454f5aa6e740ace47 183 SUPERFAMILY SSF52540 2 179 1.99E-30 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK1954 e063c36db3cddbe454f5aa6e740ace47 183 Gene3D G3DSA:3.40.50.300 1 182 5.3E-53 T 31-10-2018 TK1954 e063c36db3cddbe454f5aa6e740ace47 183 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 2 177 6.1E-13 T 31-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 TK1954 e063c36db3cddbe454f5aa6e740ace47 183 Hamap MF_00321 Probable GTP-binding protein EngB [engB]. 1 180 21.464 T 31-10-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 TK1062 3786b2036114e9039d26a0d8494dbd58 157 Pfam PF02915 Rubrerythrin 12 146 7.4E-13 T 31-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 TK1062 3786b2036114e9039d26a0d8494dbd58 157 Gene3D G3DSA:1.20.1260.10 1 152 9.2E-29 T 31-10-2018 IPR012347 Ferritin-like TK1062 3786b2036114e9039d26a0d8494dbd58 157 SUPERFAMILY SSF47240 8 151 9.4E-22 T 31-10-2018 IPR009078 Ferritin-like superfamily TK0370 9120ca39130f6bc021bc973c4cc3c5e9 202 Gene3D G3DSA:3.40.109.10 1 201 8.6E-50 T 31-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 TK0370 9120ca39130f6bc021bc973c4cc3c5e9 202 Pfam PF00881 Nitroreductase family 7 181 1.2E-36 T 31-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 TK0370 9120ca39130f6bc021bc973c4cc3c5e9 202 SUPERFAMILY SSF55469 1 201 7.85E-46 T 31-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 TK0451 2a38d4a6977cc8c77508125c7bd035f1 399 Pfam PF09658 CRISPR-associated protein (Cas_Csx9) 23 399 4.6E-261 T 31-10-2018 IPR013488 CRISPR-associated protein Csx9 TK0451 2a38d4a6977cc8c77508125c7bd035f1 399 TIGRFAM TIGR02671 cas_csx9: CRISPR-associated protein Cas8a2/Csx9, subtype I-A/APERN 23 399 4.0E-236 T 31-10-2018 IPR013488 CRISPR-associated protein Csx9 TK2064 feacb239a65dd069686341b8bc5bb5d1 427 Pfam PF01938 TRAM domain 366 423 2.2E-5 T 31-10-2018 IPR002792 TRAM domain TK2064 feacb239a65dd069686341b8bc5bb5d1 427 Gene3D G3DSA:3.80.30.20 138 369 2.8E-76 T 31-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe TK2064 feacb239a65dd069686341b8bc5bb5d1 427 Pfam PF00919 Uncharacterized protein family UPF0004 3 85 5.1E-21 T 31-10-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 TK2064 feacb239a65dd069686341b8bc5bb5d1 427 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 3 421 4.0E-130 T 31-10-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 TK2064 feacb239a65dd069686341b8bc5bb5d1 427 SUPERFAMILY SSF102114 125 363 4.05E-54 T 31-10-2018 TK2064 feacb239a65dd069686341b8bc5bb5d1 427 TIGRFAM TIGR01578 MiaB-like-B: MiaB-like tRNA modifying enzyme, archaeal-type 3 422 6.2E-141 T 31-10-2018 IPR006466 MiaB-like tRNA modifying enzyme, archaeal-type Reactome: R-HSA-6782315 TK2064 feacb239a65dd069686341b8bc5bb5d1 427 Gene3D G3DSA:3.40.50.12160 2 127 2.9E-24 T 31-10-2018 IPR038135 Methylthiotransferase, N-terminal domain superfamily TK2064 feacb239a65dd069686341b8bc5bb5d1 427 SMART SM00729 138 355 3.9E-60 T 31-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TK2064 feacb239a65dd069686341b8bc5bb5d1 427 Pfam PF04055 Radical SAM superfamily 142 314 6.4E-23 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TK2064 feacb239a65dd069686341b8bc5bb5d1 427 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 142 162 - T 31-10-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 TK1420 605b5f514e90c6319f71039814c40d20 61 Gene3D G3DSA:1.20.5.820 1 61 2.4E-24 T 31-10-2018 IPR023391 Protein translocase SecE domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TK1420 605b5f514e90c6319f71039814c40d20 61 TIGRFAM TIGR00327 secE_euk_arch: protein translocase SEC61 complex gamma subunit, archaeal and eukaryotic 5 60 1.2E-18 T 31-10-2018 IPR008158 Protein translocase SEC61 complex, gamma subunit GO:0015031|GO:0015450|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TK1420 605b5f514e90c6319f71039814c40d20 61 SUPERFAMILY SSF103456 4 58 3.79E-20 T 31-10-2018 IPR023391 Protein translocase SecE domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TK1420 605b5f514e90c6319f71039814c40d20 61 Hamap MF_00422 Protein translocase subunit SecE [secE]. 6 61 12.119 T 31-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TK1420 605b5f514e90c6319f71039814c40d20 61 ProSitePatterns PS01067 Protein secE/sec61-gamma signature. 11 39 - T 31-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TK0897 267d726dee6ddbb123c00cd919ba82ae 581 Pfam PF12836 Helix-hairpin-helix motif 525 568 1.4E-6 T 31-10-2018 TK0897 267d726dee6ddbb123c00cd919ba82ae 581 Gene3D G3DSA:3.80.30.20 200 457 7.0E-26 T 31-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe TK0897 267d726dee6ddbb123c00cd919ba82ae 581 Gene3D G3DSA:1.10.150.320 519 580 5.0E-8 T 31-10-2018 TK0897 267d726dee6ddbb123c00cd919ba82ae 581 SUPERFAMILY SSF102114 196 448 2.35E-27 T 31-10-2018 TK0897 267d726dee6ddbb123c00cd919ba82ae 581 Pfam PF04055 Radical SAM superfamily 204 403 1.9E-26 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TK0897 267d726dee6ddbb123c00cd919ba82ae 581 SUPERFAMILY SSF81585 511 580 9.15E-11 T 31-10-2018 TK0897 267d726dee6ddbb123c00cd919ba82ae 581 SMART SM00729 200 450 7.7E-32 T 31-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TK1751 06431d7a42562a9c0a4243c197002be2 123 Gene3D G3DSA:3.40.50.1010 2 123 3.2E-26 T 31-10-2018 TK1751 06431d7a42562a9c0a4243c197002be2 123 Pfam PF01850 PIN domain 4 112 4.0E-13 T 31-10-2018 IPR002716 PIN domain TK1751 06431d7a42562a9c0a4243c197002be2 123 SMART SM00670 1 110 2.5E-8 T 31-10-2018 IPR002716 PIN domain TK1751 06431d7a42562a9c0a4243c197002be2 123 SUPERFAMILY SSF88723 3 119 5.89E-27 T 31-10-2018 IPR029060 PIN-like domain superfamily TK1005 daced3acb0117da94418f2143f16149d 146 Gene3D G3DSA:1.10.287.370 1 146 4.5E-45 T 31-10-2018 IPR009053 Prefoldin TK1005 daced3acb0117da94418f2143f16149d 146 Pfam PF02996 Prefoldin subunit 18 137 1.4E-27 T 31-10-2018 IPR004127 Prefoldin alpha-like TK1005 daced3acb0117da94418f2143f16149d 146 Hamap MF_00308 Prefoldin subunit alpha [pfdA]. 3 137 16.131 T 31-10-2018 IPR011599 Prefoldin alpha subunit, archaea-type GO:0006457|GO:0016272|GO:0051082 Reactome: R-HSA-389957 TK1005 daced3acb0117da94418f2143f16149d 146 TIGRFAM TIGR00293 TIGR00293: prefoldin, alpha subunit 8 137 7.4E-37 T 31-10-2018 IPR011599 Prefoldin alpha subunit, archaea-type GO:0006457|GO:0016272|GO:0051082 Reactome: R-HSA-389957 TK1005 daced3acb0117da94418f2143f16149d 146 SUPERFAMILY SSF46579 7 139 1.49E-32 T 31-10-2018 TK0123 dab9a99159df2f536c757cc3709a8e66 414 Gene3D G3DSA:1.20.1250.20 24 209 1.6E-30 T 31-10-2018 TK0123 dab9a99159df2f536c757cc3709a8e66 414 Gene3D G3DSA:1.20.1250.20 238 414 1.0E-24 T 31-10-2018 TK0123 dab9a99159df2f536c757cc3709a8e66 414 Pfam PF07690 Major Facilitator Superfamily 35 272 1.0E-24 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TK0123 dab9a99159df2f536c757cc3709a8e66 414 SUPERFAMILY SSF103473 27 413 8.5E-59 T 31-10-2018 IPR036259 MFS transporter superfamily TK1037 002ca6f1bf86d48c9af3e92adc53927d 502 Pfam PF00149 Calcineurin-like phosphoesterase 4 187 3.8E-21 T 31-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 TK1037 002ca6f1bf86d48c9af3e92adc53927d 502 SUPERFAMILY SSF56300 257 488 1.65E-32 T 31-10-2018 TK1037 002ca6f1bf86d48c9af3e92adc53927d 502 SUPERFAMILY SSF56300 4 237 1.83E-50 T 31-10-2018 TK1037 002ca6f1bf86d48c9af3e92adc53927d 502 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 281 475 2.5E-6 T 31-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 TK1037 002ca6f1bf86d48c9af3e92adc53927d 502 Gene3D G3DSA:3.60.21.10 256 495 2.4E-22 T 31-10-2018 IPR029052 Metallo-dependent phosphatase-like TK1037 002ca6f1bf86d48c9af3e92adc53927d 502 Gene3D G3DSA:3.60.21.10 2 255 2.0E-41 T 31-10-2018 IPR029052 Metallo-dependent phosphatase-like TK2020 2afded9f98fe3ac7d137f78ca7e07b3f 248 Pfam PF00005 ABC transporter 19 163 6.2E-28 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TK2020 2afded9f98fe3ac7d137f78ca7e07b3f 248 SMART SM00382 28 210 7.7E-16 T 31-10-2018 IPR003593 AAA+ ATPase domain TK2020 2afded9f98fe3ac7d137f78ca7e07b3f 248 SUPERFAMILY SSF52540 4 219 4.24E-59 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK2020 2afded9f98fe3ac7d137f78ca7e07b3f 248 Gene3D G3DSA:3.40.50.300 3 241 1.0E-65 T 31-10-2018 TK2020 2afded9f98fe3ac7d137f78ca7e07b3f 248 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TK0561 cf031e65aefc67b2f2035b6c18b76db2 454 Gene3D G3DSA:1.20.200.10 101 358 4.3E-95 T 31-10-2018 TK0561 cf031e65aefc67b2f2035b6c18b76db2 454 ProSitePatterns PS00163 Fumarate lyases signature. 272 281 - T 31-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 TK0561 cf031e65aefc67b2f2035b6c18b76db2 454 PRINTS PR00145 Argininosuccinate lyase family signature 227 251 5.2E-11 T 31-10-2018 TK0561 cf031e65aefc67b2f2035b6c18b76db2 454 PRINTS PR00145 Argininosuccinate lyase family signature 272 288 5.2E-11 T 31-10-2018 TK0561 cf031e65aefc67b2f2035b6c18b76db2 454 PRINTS PR00145 Argininosuccinate lyase family signature 95 117 5.2E-11 T 31-10-2018 TK0561 cf031e65aefc67b2f2035b6c18b76db2 454 PRINTS PR00145 Argininosuccinate lyase family signature 136 156 5.2E-11 T 31-10-2018 TK0561 cf031e65aefc67b2f2035b6c18b76db2 454 SUPERFAMILY SSF48557 4 441 5.81E-135 T 31-10-2018 IPR008948 L-Aspartase-like GO:0003824 TK0561 cf031e65aefc67b2f2035b6c18b76db2 454 Pfam PF00206 Lyase 13 293 8.7E-58 T 31-10-2018 IPR022761 Fumarate lyase, N-terminal TK0561 cf031e65aefc67b2f2035b6c18b76db2 454 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 6 438 3.3E-188 T 31-10-2018 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TK0561 cf031e65aefc67b2f2035b6c18b76db2 454 Gene3D G3DSA:1.10.275.10 1 100 1.5E-37 T 31-10-2018 IPR024083 Fumarase/histidase, N-terminal TK0561 cf031e65aefc67b2f2035b6c18b76db2 454 Pfam PF10397 Adenylosuccinate lyase C-terminus 362 438 9.2E-20 T 31-10-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TK0561 cf031e65aefc67b2f2035b6c18b76db2 454 PRINTS PR00149 Fumarate lyase superfamily signature 272 288 2.6E-27 T 31-10-2018 IPR000362 Fumarate lyase family TK0561 cf031e65aefc67b2f2035b6c18b76db2 454 PRINTS PR00149 Fumarate lyase superfamily signature 227 254 2.6E-27 T 31-10-2018 IPR000362 Fumarate lyase family TK0561 cf031e65aefc67b2f2035b6c18b76db2 454 PRINTS PR00149 Fumarate lyase superfamily signature 96 114 2.6E-27 T 31-10-2018 IPR000362 Fumarate lyase family TK0561 cf031e65aefc67b2f2035b6c18b76db2 454 PRINTS PR00149 Fumarate lyase superfamily signature 141 159 2.6E-27 T 31-10-2018 IPR000362 Fumarate lyase family TK0561 cf031e65aefc67b2f2035b6c18b76db2 454 SMART SM00998 360 439 6.2E-33 T 31-10-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TK0561 cf031e65aefc67b2f2035b6c18b76db2 454 Gene3D G3DSA:1.10.40.30 359 439 6.7E-24 T 31-10-2018 TK0538 0ae56c18a98485ba3ec024c24f36e7e5 177 SUPERFAMILY SSF55729 3 171 4.58E-41 T 31-10-2018 IPR016181 Acyl-CoA N-acyltransferase TK0538 0ae56c18a98485ba3ec024c24f36e7e5 177 Pfam PF13302 Acetyltransferase (GNAT) domain 16 149 1.9E-28 T 31-10-2018 IPR000182 GNAT domain TK0538 0ae56c18a98485ba3ec024c24f36e7e5 177 Gene3D G3DSA:3.40.630.30 1 177 4.0E-44 T 31-10-2018 TK0239 e60bdfa900e702396a3c20c2d61a712f 109 Gene3D G3DSA:2.40.50.140 1 109 2.9E-35 T 31-10-2018 TK0239 e60bdfa900e702396a3c20c2d61a712f 109 TIGRFAM TIGR00399 metG_C_term: methionine--tRNA ligase, beta subunit 3 108 8.9E-36 T 31-10-2018 IPR004495 Methionyl-tRNA synthetase, beta subunit, C-terminal GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 TK0239 e60bdfa900e702396a3c20c2d61a712f 109 SUPERFAMILY SSF50249 7 108 7.1E-31 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold TK0239 e60bdfa900e702396a3c20c2d61a712f 109 Pfam PF01588 Putative tRNA binding domain 14 107 8.1E-26 T 31-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 TK1328 cb47de8267923135636a18940fd6ecdb 253 PIRSF PIRSF017269 1 253 7.2E-79 T 31-10-2018 IPR014816 tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 GO:0016429|GO:0030488|GO:0031515 MetaCyc: PWY-6829 TK1328 cb47de8267923135636a18940fd6ecdb 253 Gene3D G3DSA:3.40.50.150 63 253 3.8E-67 T 31-10-2018 TK1328 cb47de8267923135636a18940fd6ecdb 253 Gene3D G3DSA:3.10.330.20 1 61 2.3E-24 T 31-10-2018 TK1328 cb47de8267923135636a18940fd6ecdb 253 Pfam PF08704 tRNA methyltransferase complex GCD14 subunit 74 232 1.3E-26 T 31-10-2018 IPR014816 tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 GO:0016429|GO:0030488|GO:0031515 MetaCyc: PWY-6829 TK1328 cb47de8267923135636a18940fd6ecdb 253 SUPERFAMILY SSF53335 1 252 8.36E-77 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TK1328 cb47de8267923135636a18940fd6ecdb 253 Pfam PF14801 tRNA methyltransferase complex GCD14 subunit N-term 3 45 2.2E-8 T 31-10-2018 TK0458 a4033898a0ab6e554e5116a004d2014e 170 Pfam PF01930 Domain of unknown function DUF83 14 169 1.4E-54 T 31-10-2018 IPR022765 Dna2/Cas4, domain of unknown function DUF83 TK0458 a4033898a0ab6e554e5116a004d2014e 170 TIGRFAM TIGR00372 cas4: CRISPR-associated protein Cas4 15 169 5.7E-25 T 31-10-2018 IPR013343 CRISPR-associated protein Cas4 TK0458 a4033898a0ab6e554e5116a004d2014e 170 Gene3D G3DSA:3.90.320.10 10 170 1.7E-9 T 31-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal TK1039 d528ff9e375ac35f30a7525e03195a28 432 Hamap MF_01908 Cyclic 2,3-diphosphoglycerate synthetase [cpgS]. 1 432 53.334 T 31-10-2018 IPR016557 Cyclic 2, 3-diphospoglycerate synthetase GO:0005737|GO:0006094|GO:0036356 TK1039 d528ff9e375ac35f30a7525e03195a28 432 PIRSF PIRSF009445 1 432 1.1E-215 T 31-10-2018 IPR016557 Cyclic 2, 3-diphospoglycerate synthetase GO:0005737|GO:0006094|GO:0036356 TK2209 611adbbe4257bca4ab973ef78661b8e9 337 Gene3D G3DSA:1.10.3470.10 2 334 2.2E-90 T 31-10-2018 IPR037294 ABC transporter, BtuC-like TK2209 611adbbe4257bca4ab973ef78661b8e9 337 Pfam PF01032 FecCD transport family 13 329 1.4E-82 T 31-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 TK2209 611adbbe4257bca4ab973ef78661b8e9 337 SUPERFAMILY SSF81345 4 329 8.24E-74 T 31-10-2018 IPR037294 ABC transporter, BtuC-like TK0685 28033535dd52f71ef59de202ce2e788b 257 Gene3D G3DSA:3.30.1600.10 29 168 6.2E-95 T 31-10-2018 IPR026591 Sirtuin, catalytic core small domain superfamily TK0685 28033535dd52f71ef59de202ce2e788b 257 Hamap MF_01121 NAD-dependent protein deacylase [cobB]. 13 248 62.467 T 31-10-2018 IPR027546 Sirtuin, class III GO:0036054|GO:0036055|GO:0070403 Reactome: R-HSA-2151201 TK0685 28033535dd52f71ef59de202ce2e788b 257 SUPERFAMILY SSF52467 3 250 3.82E-93 T 31-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily TK0685 28033535dd52f71ef59de202ce2e788b 257 Pfam PF02146 Sir2 family 20 198 1.6E-60 T 31-10-2018 IPR003000 Sirtuin family GO:0070403 TK0685 28033535dd52f71ef59de202ce2e788b 257 Gene3D G3DSA:3.40.50.1220 12 242 6.2E-95 T 31-10-2018 TK1719 4955d86e75dce6552198162d5cc38eeb 429 Pfam PF01943 Polysaccharide biosynthesis protein 18 285 1.3E-15 T 31-10-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 TK0494 beeeaae8af404d5a185c604ead1799b2 384 Pfam PF01546 Peptidase family M20/M25/M40 70 375 3.6E-38 T 31-10-2018 IPR002933 Peptidase M20 GO:0016787 TK0494 beeeaae8af404d5a185c604ead1799b2 384 Gene3D G3DSA:3.30.70.360 178 292 7.8E-147 T 31-10-2018 TK0494 beeeaae8af404d5a185c604ead1799b2 384 Pfam PF07687 Peptidase dimerisation domain 186 276 3.1E-11 T 31-10-2018 IPR011650 Peptidase M20, dimerisation domain TK0494 beeeaae8af404d5a185c604ead1799b2 384 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 16 370 7.6E-120 T 31-10-2018 IPR017439 Amidohydrolase GO:0016787 TK0494 beeeaae8af404d5a185c604ead1799b2 384 SUPERFAMILY SSF53187 10 382 4.0E-89 T 31-10-2018 TK0494 beeeaae8af404d5a185c604ead1799b2 384 PIRSF PIRSF005962 1 384 3.5E-135 T 31-10-2018 IPR017439 Amidohydrolase GO:0016787 TK0494 beeeaae8af404d5a185c604ead1799b2 384 SUPERFAMILY SSF55031 181 287 1.44E-30 T 31-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain TK0494 beeeaae8af404d5a185c604ead1799b2 384 Gene3D G3DSA:3.40.630.10 16 367 7.8E-147 T 31-10-2018 TK0169 8567f999bd7ee8530ecce29bb987f066 182 Gene3D G3DSA:1.10.10.10 1 87 3.2E-24 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TK0169 8567f999bd7ee8530ecce29bb987f066 182 SMART SM00347 16 110 0.0061 T 31-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TK0169 8567f999bd7ee8530ecce29bb987f066 182 PIRSF PIRSF006707 2 178 3.2E-51 T 31-10-2018 IPR026282 DNA-binding protein, MJ1563 type TK0169 8567f999bd7ee8530ecce29bb987f066 182 SUPERFAMILY SSF46785 3 135 1.49E-22 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TK0169 8567f999bd7ee8530ecce29bb987f066 182 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 20 87 1.9E-6 T 31-10-2018 IPR002831 Transcription regulator TrmB, N-terminal TK1859 094640192546a7ad8b42d1857b44f0e2 226 Gene3D G3DSA:3.40.50.300 1 223 1.9E-65 T 31-10-2018 TK1859 094640192546a7ad8b42d1857b44f0e2 226 SMART SM00382 28 215 4.3E-14 T 31-10-2018 IPR003593 AAA+ ATPase domain TK1859 094640192546a7ad8b42d1857b44f0e2 226 SUPERFAMILY SSF52540 1 219 3.33E-62 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK1859 094640192546a7ad8b42d1857b44f0e2 226 Pfam PF00005 ABC transporter 19 167 5.5E-30 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TK1859 094640192546a7ad8b42d1857b44f0e2 226 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TK0791 3085b0cd0262814349ca00ba11713f52 88 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 7 86 5.8E-10 T 31-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family TK0791 3085b0cd0262814349ca00ba11713f52 88 SUPERFAMILY SSF143011 6 86 1.83E-21 T 31-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily TK0791 3085b0cd0262814349ca00ba11713f52 88 Gene3D G3DSA:3.30.2310.20 1 88 5.9E-22 T 31-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily TK2111 8719f32d457873b35a7c1d522c97ba94 184 SUPERFAMILY SSF52972 1 182 8.9E-65 T 31-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like TK2111 8719f32d457873b35a7c1d522c97ba94 184 Hamap MF_01405 dITP/XTP pyrophosphatase. 1 181 43.486 T 31-10-2018 IPR020922 dITP/XTP pyrophosphatase GO:0009143|GO:0017111 KEGG: 00230+3.6.1.66 TK2111 8719f32d457873b35a7c1d522c97ba94 184 Gene3D G3DSA:3.90.950.10 1 184 7.2E-75 T 31-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like TK2111 8719f32d457873b35a7c1d522c97ba94 184 Pfam PF01725 Ham1 family 3 178 7.7E-53 T 31-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 TK2111 8719f32d457873b35a7c1d522c97ba94 184 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 3 179 2.3E-65 T 31-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 TK2078 f7f652feb6f429670a66af0282f7a557 162 Pfam PF12838 4Fe-4S dicluster domain 29 78 1.2E-13 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TK2078 f7f652feb6f429670a66af0282f7a557 162 Gene3D G3DSA:3.30.70.3270 50 103 4.9E-7 T 31-10-2018 TK2078 f7f652feb6f429670a66af0282f7a557 162 Gene3D G3DSA:3.30.70.20 7 49 9.8E-10 T 31-10-2018 TK2078 f7f652feb6f429670a66af0282f7a557 162 SUPERFAMILY SSF54862 22 151 2.51E-21 T 31-10-2018 TK2078 f7f652feb6f429670a66af0282f7a557 162 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 29 40 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TK1800 dda140cc19e0bcbbdbf684b915e87dee 335 ProSitePatterns PS00211 ABC transporters family signature. 164 178 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TK1800 dda140cc19e0bcbbdbf684b915e87dee 335 Gene3D G3DSA:3.40.50.300 3 335 2.2E-96 T 31-10-2018 TK1800 dda140cc19e0bcbbdbf684b915e87dee 335 Pfam PF00005 ABC transporter 37 191 1.2E-31 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TK1800 dda140cc19e0bcbbdbf684b915e87dee 335 SMART SM00382 45 249 2.6E-11 T 31-10-2018 IPR003593 AAA+ ATPase domain TK1800 dda140cc19e0bcbbdbf684b915e87dee 335 SUPERFAMILY SSF52540 5 263 9.29E-71 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK1800 dda140cc19e0bcbbdbf684b915e87dee 335 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 241 331 7.2E-28 T 31-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TK1800 dda140cc19e0bcbbdbf684b915e87dee 335 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 243 311 2.6E-20 T 31-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TK1509 4fd4ccc8d2ed8204ea74c37103b0920a 338 SUPERFAMILY SSF88697 249 332 8.29E-23 T 31-10-2018 IPR015947 PUA-like superfamily TK1509 4fd4ccc8d2ed8204ea74c37103b0920a 338 Pfam PF01472 PUA domain 251 323 4.2E-20 T 31-10-2018 IPR002478 PUA domain GO:0003723 TK1509 4fd4ccc8d2ed8204ea74c37103b0920a 338 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 181 247 8.1E-24 T 31-10-2018 IPR032819 tRNA pseudouridylate synthase B, C-terminal Reactome: R-HSA-171319|Reactome: R-HSA-6790901 TK1509 4fd4ccc8d2ed8204ea74c37103b0920a 338 TIGRFAM TIGR00425 CBF5: putative rRNA pseudouridine synthase 18 335 1.6E-138 T 31-10-2018 IPR004802 tRNA pseudouridine synthase B family GO:0006396 Reactome: R-HSA-171319|Reactome: R-HSA-6790901 TK1509 4fd4ccc8d2ed8204ea74c37103b0920a 338 Gene3D G3DSA:2.30.130.70 23 332 2.1E-149 T 31-10-2018 TK1509 4fd4ccc8d2ed8204ea74c37103b0920a 338 Hamap MF_01081 Probable tRNA pseudouridine synthase B [truB]. 40 325 51.93 T 31-10-2018 IPR026326 Probable tRNA pseudouridine synthase B, archaeal GO:0006396 TK1509 4fd4ccc8d2ed8204ea74c37103b0920a 338 SMART SM01136 4 63 5.1E-27 T 31-10-2018 IPR012960 Dyskerin-like Reactome: R-HSA-171319|Reactome: R-HSA-6790901 TK1509 4fd4ccc8d2ed8204ea74c37103b0920a 338 TIGRFAM TIGR00451 unchar_dom_2: uncharacterized domain 2 240 320 9.4E-11 T 31-10-2018 IPR004521 Uncharacterised domain CHP00451 GO:0003723 TK1509 4fd4ccc8d2ed8204ea74c37103b0920a 338 Gene3D G3DSA:3.30.2350.10 40 243 2.1E-149 T 31-10-2018 TK1509 4fd4ccc8d2ed8204ea74c37103b0920a 338 Pfam PF08068 DKCLD (NUC011) domain 15 63 1.3E-19 T 31-10-2018 IPR012960 Dyskerin-like Reactome: R-HSA-171319|Reactome: R-HSA-6790901 TK1509 4fd4ccc8d2ed8204ea74c37103b0920a 338 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 67 180 7.9E-22 T 31-10-2018 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 TK1509 4fd4ccc8d2ed8204ea74c37103b0920a 338 SUPERFAMILY SSF55120 18 247 1.04E-77 T 31-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 TK1509 4fd4ccc8d2ed8204ea74c37103b0920a 338 SMART SM00359 251 325 2.5E-21 T 31-10-2018 IPR002478 PUA domain GO:0003723 TK2055 d82c3fdd68e7de1e965fd65ca0d45bb2 515 Pfam PF12679 ABC-2 family transporter protein 316 514 4.4E-14 T 31-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 TK0882 35228bd9d101e7d36a16160659a45c80 288 TIGRFAM TIGR01230 agmatinase: agmatinase 20 277 2.0E-68 T 31-10-2018 IPR005925 Agmatinase-related KEGG: 00330+3.5.3.11|MetaCyc: PWY-40|MetaCyc: PWY-6305|Reactome: R-HSA-351143 TK0882 35228bd9d101e7d36a16160659a45c80 288 Pfam PF00491 Arginase family 23 278 5.1E-62 T 31-10-2018 IPR006035 Ureohydrolase GO:0046872 TK0882 35228bd9d101e7d36a16160659a45c80 288 PIRSF PIRSF036979 1 286 2.9E-83 T 31-10-2018 IPR006035 Ureohydrolase GO:0046872 TK0882 35228bd9d101e7d36a16160659a45c80 288 Gene3D G3DSA:3.40.800.10 5 286 2.7E-74 T 31-10-2018 TK0882 35228bd9d101e7d36a16160659a45c80 288 SUPERFAMILY SSF52768 16 284 1.98E-72 T 31-10-2018 IPR023696 Ureohydrolase domain superfamily TK0573 abbe71e2499fa1ff8bc22453a6d6ef2c 185 Gene3D G3DSA:1.20.58.290 58 175 9.6E-10 T 31-10-2018 TK0573 abbe71e2499fa1ff8bc22453a6d6ef2c 185 Gene3D G3DSA:2.30.110.10 18 128 9.6E-10 T 31-10-2018 IPR012349 FMN-binding split barrel GO:0048037 TK0573 abbe71e2499fa1ff8bc22453a6d6ef2c 185 Pfam PF04289 Protein of unknown function (DUF447) 11 179 4.2E-35 T 31-10-2018 IPR007386 Protein of unknown function DUF447 TK0573 abbe71e2499fa1ff8bc22453a6d6ef2c 185 PIRSF PIRSF018747 2 185 7.7E-39 T 31-10-2018 IPR016733 Uncharacterised conserved protein UCP018747 TK0573 abbe71e2499fa1ff8bc22453a6d6ef2c 185 SUPERFAMILY SSF50475 4 183 1.18E-34 T 31-10-2018 TK1512 99fc67d6040c1e5ba77e4655faddfcc7 236 Gene3D G3DSA:3.40.50.720 1 233 1.3E-56 T 31-10-2018 TK1512 99fc67d6040c1e5ba77e4655faddfcc7 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 74 85 3.8E-14 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TK1512 99fc67d6040c1e5ba77e4655faddfcc7 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 145 164 3.8E-14 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TK1512 99fc67d6040c1e5ba77e4655faddfcc7 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 3.8E-14 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TK1512 99fc67d6040c1e5ba77e4655faddfcc7 236 SUPERFAMILY SSF51735 1 211 1.08E-52 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily TK1512 99fc67d6040c1e5ba77e4655faddfcc7 236 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 145 164 5.6E-5 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TK1512 99fc67d6040c1e5ba77e4655faddfcc7 236 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 74 85 5.6E-5 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TK1512 99fc67d6040c1e5ba77e4655faddfcc7 236 Pfam PF00106 short chain dehydrogenase 2 184 1.2E-42 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TK0708 2303c0dd03dd040105d02dbefccfa39c 253 Gene3D G3DSA:3.40.50.300 1 244 4.3E-68 T 31-10-2018 TK0708 2303c0dd03dd040105d02dbefccfa39c 253 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TK0708 2303c0dd03dd040105d02dbefccfa39c 253 Pfam PF00005 ABC transporter 17 164 9.2E-27 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TK0708 2303c0dd03dd040105d02dbefccfa39c 253 SUPERFAMILY SSF52540 1 228 6.48E-61 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK0708 2303c0dd03dd040105d02dbefccfa39c 253 SMART SM00382 25 210 2.8E-13 T 31-10-2018 IPR003593 AAA+ ATPase domain TK1609 bb359af6ea7b9314dc7cc3a51927e327 235 Pfam PF03192 Pyrococcus protein of unknown function, DUF257 19 219 7.6E-71 T 31-10-2018 IPR005489 Protein of unknown function DUF257 TK1609 bb359af6ea7b9314dc7cc3a51927e327 235 Gene3D G3DSA:3.40.50.11570 16 217 4.3E-47 T 31-10-2018 TK0695 8d5ea180253658454358be9e8377e8d4 108 Pfam PF01402 Ribbon-helix-helix protein, copG family 10 47 5.4E-6 T 31-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 TK0695 8d5ea180253658454358be9e8377e8d4 108 PIRSF PIRSF019108 1 108 5.4E-53 T 31-10-2018 IPR016748 Transcription regulator, CopG/Arc/MetJ DNA-binding domain-containing, predicted TK0695 8d5ea180253658454358be9e8377e8d4 108 SUPERFAMILY SSF47598 9 50 1.7E-7 T 31-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 TK0290 df5a36b4efb65136f0760c5394db0661 306 Pfam PF04055 Radical SAM superfamily 27 238 9.9E-24 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TK0290 df5a36b4efb65136f0760c5394db0661 306 ProSitePatterns PS01087 Radical activating enzymes signature. 20 41 - T 31-10-2018 IPR001989 Radical-activating enzyme, conserved site GO:0016491|GO:0051539|GO:0055114 TK0290 df5a36b4efb65136f0760c5394db0661 306 TIGRFAM TIGR02494 PFLE_PFLC: glycyl-radical enzyme activating protein 9 299 1.6E-107 T 31-10-2018 TK0290 df5a36b4efb65136f0760c5394db0661 306 Gene3D G3DSA:3.30.70.20 53 100 2.6E-13 T 31-10-2018 TK0290 df5a36b4efb65136f0760c5394db0661 306 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 88 99 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TK0290 df5a36b4efb65136f0760c5394db0661 306 PIRSF PIRSF000371 2 306 2.0E-102 T 31-10-2018 IPR012839 Organic radical enzyme activase GO:0016491|GO:0055114 TK0290 df5a36b4efb65136f0760c5394db0661 306 SUPERFAMILY SSF54862 10 148 6.67E-25 T 31-10-2018 TK0290 df5a36b4efb65136f0760c5394db0661 306 SUPERFAMILY SSF102114 97 263 4.51E-18 T 31-10-2018 TK0290 df5a36b4efb65136f0760c5394db0661 306 Pfam PF13353 4Fe-4S single cluster domain 19 181 3.6E-13 T 31-10-2018 TK1588 b940b2c6c6adfbc6c40b085a1f1ed97b 218 SMART SM00382 26 209 4.7E-5 T 31-10-2018 IPR003593 AAA+ ATPase domain TK1588 b940b2c6c6adfbc6c40b085a1f1ed97b 218 ProSitePatterns PS00211 ABC transporters family signature. 125 139 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TK1588 b940b2c6c6adfbc6c40b085a1f1ed97b 218 SUPERFAMILY SSF52540 2 214 9.02E-48 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK1588 b940b2c6c6adfbc6c40b085a1f1ed97b 218 Gene3D G3DSA:3.40.50.300 1 216 2.1E-46 T 31-10-2018 TK1588 b940b2c6c6adfbc6c40b085a1f1ed97b 218 Pfam PF00005 ABC transporter 18 153 1.9E-21 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TK0828 f7fa8bd4ad761936e188cbc615c0a088 361 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 267 2.8E-55 T 31-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TK0828 f7fa8bd4ad761936e188cbc615c0a088 361 Gene3D G3DSA:3.30.390.30 299 359 7.0E-27 T 31-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 TK0828 f7fa8bd4ad761936e188cbc615c0a088 361 Gene3D G3DSA:3.50.50.60 106 223 1.9E-101 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TK0828 f7fa8bd4ad761936e188cbc615c0a088 361 SUPERFAMILY SSF51905 1 289 1.54E-40 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TK0828 f7fa8bd4ad761936e188cbc615c0a088 361 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 250 268 2.0E-8 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TK0828 f7fa8bd4ad761936e188cbc615c0a088 361 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 2 24 2.0E-8 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TK0828 f7fa8bd4ad761936e188cbc615c0a088 361 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 133 157 2.0E-8 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TK0828 f7fa8bd4ad761936e188cbc615c0a088 361 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 95 103 2.0E-8 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TK0828 f7fa8bd4ad761936e188cbc615c0a088 361 SUPERFAMILY SSF55424 290 351 4.67E-28 T 31-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 TK0828 f7fa8bd4ad761936e188cbc615c0a088 361 Gene3D G3DSA:3.50.50.60 3 275 1.9E-101 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TK0828 f7fa8bd4ad761936e188cbc615c0a088 361 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 215 231 3.7E-23 T 31-10-2018 TK0828 f7fa8bd4ad761936e188cbc615c0a088 361 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 137 155 3.7E-23 T 31-10-2018 TK0828 f7fa8bd4ad761936e188cbc615c0a088 361 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 94 112 3.7E-23 T 31-10-2018 TK0828 f7fa8bd4ad761936e188cbc615c0a088 361 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 3 22 3.7E-23 T 31-10-2018 TK0828 f7fa8bd4ad761936e188cbc615c0a088 361 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 240 262 3.7E-23 T 31-10-2018 TK0688 20f584512f301ac09828d58b91f4f7a8 213 Pfam PF01569 PAP2 superfamily 76 179 2.0E-18 T 31-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase TK0688 20f584512f301ac09828d58b91f4f7a8 213 SMART SM00014 76 184 4.0E-6 T 31-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase TK0688 20f584512f301ac09828d58b91f4f7a8 213 Gene3D G3DSA:1.20.144.10 103 200 8.1E-13 T 31-10-2018 TK0688 20f584512f301ac09828d58b91f4f7a8 213 SUPERFAMILY SSF48317 29 193 3.27E-28 T 31-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily TK0793 70d00666aac01e7ea226cb486f66adb3 267 Hamap MF_01527_A GTP cyclohydrolase FolE2 [folE2]. 1 267 26.6 T 31-10-2018 IPR022840 GTP cyclohydrolase MptA GO:0003933 KEGG: 00790+3.5.4.39|MetaCyc: PWY-6797|MetaCyc: PWY-7853 TK0793 70d00666aac01e7ea226cb486f66adb3 267 Pfam PF02649 Type I GTP cyclohydrolase folE2 4 263 2.2E-65 T 31-10-2018 IPR003801 GTP cyclohydrolase FolE2/MptA GO:0003933 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852 TK0793 70d00666aac01e7ea226cb486f66adb3 267 Gene3D G3DSA:3.10.270.10 1 266 4.3E-67 T 31-10-2018 TK0180 6a7539b8d45d1d7eed9023c7e1c2b29d 388 PIRSF PIRSF000429 1 386 1.5E-64 T 31-10-2018 IPR002155 Thiolase GO:0016747 TK0180 6a7539b8d45d1d7eed9023c7e1c2b29d 388 SUPERFAMILY SSF53901 5 229 6.76E-44 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 TK0180 6a7539b8d45d1d7eed9023c7e1c2b29d 388 Pfam PF02803 Thiolase, C-terminal domain 260 355 5.2E-11 T 31-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 TK0180 6a7539b8d45d1d7eed9023c7e1c2b29d 388 SUPERFAMILY SSF53901 246 375 5.95E-29 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 TK0180 6a7539b8d45d1d7eed9023c7e1c2b29d 388 Gene3D G3DSA:3.40.47.10 5 387 4.0E-122 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 TK0180 6a7539b8d45d1d7eed9023c7e1c2b29d 388 Pfam PF00108 Thiolase, N-terminal domain 5 221 2.1E-24 T 31-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 TK2156 b5fe6a923e3f9ccbe9ad9e4a99999bff 568 SUPERFAMILY SSF51713 1 243 3.4E-23 T 31-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 TK2156 b5fe6a923e3f9ccbe9ad9e4a99999bff 568 Gene3D G3DSA:2.30.130.10 502 568 6.2E-25 T 31-10-2018 IPR036974 PUA domain superfamily GO:0003723 TK2156 b5fe6a923e3f9ccbe9ad9e4a99999bff 568 TIGRFAM TIGR00451 unchar_dom_2: uncharacterized domain 2 511 565 2.7E-9 T 31-10-2018 IPR004521 Uncharacterised domain CHP00451 GO:0003723 TK2156 b5fe6a923e3f9ccbe9ad9e4a99999bff 568 Pfam PF01472 PUA domain 512 566 1.6E-10 T 31-10-2018 IPR002478 PUA domain GO:0003723 TK2156 b5fe6a923e3f9ccbe9ad9e4a99999bff 568 Gene3D G3DSA:3.40.50.10630 252 423 1.4E-47 T 31-10-2018 TK2156 b5fe6a923e3f9ccbe9ad9e4a99999bff 568 SUPERFAMILY SSF52141 265 421 4.05E-41 T 31-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 TK2156 b5fe6a923e3f9ccbe9ad9e4a99999bff 568 SMART SM00359 502 568 1.2E-8 T 31-10-2018 IPR002478 PUA domain GO:0003723 TK2156 b5fe6a923e3f9ccbe9ad9e4a99999bff 568 Pfam PF14810 Patch-forming domain C2 of tRNA-guanine transglycosylase 438 500 1.7E-6 T 31-10-2018 IPR029402 tRNA-guanine transglycosylase, patch-forming domain C2 MetaCyc: PWY-6711|MetaCyc: PWY-7923 TK2156 b5fe6a923e3f9ccbe9ad9e4a99999bff 568 SUPERFAMILY SSF88697 511 567 3.36E-13 T 31-10-2018 IPR015947 PUA-like superfamily TK2156 b5fe6a923e3f9ccbe9ad9e4a99999bff 568 SUPERFAMILY SSF88802 247 500 4.51E-17 T 31-10-2018 TK1379 649706316d50e20d8b18f2236c3f28b9 502 Pfam PF02347 Glycine cleavage system P-protein 33 305 2.9E-10 T 31-10-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 TK1379 649706316d50e20d8b18f2236c3f28b9 502 Gene3D G3DSA:3.40.640.10 86 318 2.6E-60 T 31-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TK1379 649706316d50e20d8b18f2236c3f28b9 502 SUPERFAMILY SSF53383 12 488 5.86E-120 T 31-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TK1379 649706316d50e20d8b18f2236c3f28b9 502 Hamap MF_00713 Probable glycine dehydrogenase (decarboxylating) subunit 2 [gcvPB]. 10 490 60.889 T 31-10-2018 IPR023012 Probable glycine dehydrogenase (decarboxylating) subunit 2 GO:0004375|GO:0019464 KEGG: 00260+1.4.4.2 TK1379 649706316d50e20d8b18f2236c3f28b9 502 Gene3D G3DSA:3.90.1150.10 340 475 2.1E-42 T 31-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TK0667 d5077f5da71adf9807573d886e8920f2 235 Gene3D G3DSA:3.60.21.10 2 235 7.0E-72 T 31-10-2018 IPR029052 Metallo-dependent phosphatase-like TK0667 d5077f5da71adf9807573d886e8920f2 235 TIGRFAM TIGR00040 yfcE: phosphodiesterase, MJ0936 family 1 197 5.8E-18 T 31-10-2018 IPR000979 Phosphodiesterase MJ0936/Vps29 Reactome: R-HSA-3238698 TK0667 d5077f5da71adf9807573d886e8920f2 235 PIRSF PIRSF000883 1 235 2.0E-74 T 31-10-2018 IPR011152 Phosphoesterase MJ0912 TK0667 d5077f5da71adf9807573d886e8920f2 235 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 1 196 1.7E-31 T 31-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 TK0667 d5077f5da71adf9807573d886e8920f2 235 SUPERFAMILY SSF56300 1 234 4.29E-67 T 31-10-2018 TK0768 2fca4c4e21b54de04771111c8d00a5f0 94 SUPERFAMILY SSF69786 2 92 3.4E-30 T 31-10-2018 IPR036591 YggU-like superfamily TK0768 2fca4c4e21b54de04771111c8d00a5f0 94 SMART SM01152 7 82 2.3E-36 T 31-10-2018 IPR003746 Protein of unknown function DUF167 TK0768 2fca4c4e21b54de04771111c8d00a5f0 94 TIGRFAM TIGR00251 TIGR00251: TIGR00251 family protein 4 82 4.2E-30 T 31-10-2018 IPR005228 Conserved hypothetical protein CHP00251 TK0768 2fca4c4e21b54de04771111c8d00a5f0 94 Gene3D G3DSA:3.30.1200.10 1 94 1.8E-33 T 31-10-2018 IPR036591 YggU-like superfamily TK0768 2fca4c4e21b54de04771111c8d00a5f0 94 Hamap MF_00634 UPF0235 protein YggU [yggU]. 7 94 21.842 T 31-10-2018 IPR003746 Protein of unknown function DUF167 TK0768 2fca4c4e21b54de04771111c8d00a5f0 94 Pfam PF02594 Uncharacterised ACR, YggU family COG1872 10 80 2.5E-25 T 31-10-2018 IPR003746 Protein of unknown function DUF167 TK1248 6eb1e9a5ee68a93be5e8f85896fb8ad5 133 PIRSF PIRSF004966 1 131 9.5E-57 T 31-10-2018 IPR012016 Aconitase X subunit 2, putative TK1248 6eb1e9a5ee68a93be5e8f85896fb8ad5 133 Hamap MF_00078 UPF0107 protein . 2 129 34.212 T 31-10-2018 IPR020794 Aconitase X subunit 2, archaeal, putative TK1248 6eb1e9a5ee68a93be5e8f85896fb8ad5 133 Pfam PF01989 Protein of unknown function DUF126 24 103 4.0E-36 T 31-10-2018 IPR002840 Aconitase X swivel domain, putative TK1248 6eb1e9a5ee68a93be5e8f85896fb8ad5 133 SUPERFAMILY SSF52016 1 129 6.28E-46 T 31-10-2018 TK1248 6eb1e9a5ee68a93be5e8f85896fb8ad5 133 Gene3D G3DSA:3.50.30.10 1 132 1.4E-51 T 31-10-2018 TK0320 ac13a8001e25e022207a3440fbdfee35 239 Pfam PF01904 Protein of unknown function DUF72 15 234 6.9E-39 T 31-10-2018 IPR002763 Protein of unknown function DUF72 TK0320 ac13a8001e25e022207a3440fbdfee35 239 Gene3D G3DSA:3.20.20.410 1 239 4.2E-43 T 31-10-2018 IPR036520 UPF0759 superfamily TK0320 ac13a8001e25e022207a3440fbdfee35 239 SUPERFAMILY SSF117396 1 237 1.09E-48 T 31-10-2018 IPR036520 UPF0759 superfamily TK0112 53b6aa0d0f6ee5473d2216f5ee71dd29 91 SMART SM00888 5 91 8.6E-34 T 31-10-2018 IPR014038 Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain GO:0003746|GO:0006414 Reactome: R-HSA-156842 TK0112 53b6aa0d0f6ee5473d2216f5ee71dd29 91 TIGRFAM TIGR00489 aEF-1_beta: translation elongation factor aEF-1 beta 7 90 2.6E-21 T 31-10-2018 IPR004542 Translation elongation factor EF1B, beta chain, archaeal GO:0003746|GO:0006414 TK0112 53b6aa0d0f6ee5473d2216f5ee71dd29 91 Hamap MF_00043 Elongation factor 1-beta [ef1b]. 1 91 40.9 T 31-10-2018 IPR004542 Translation elongation factor EF1B, beta chain, archaeal GO:0003746|GO:0006414 TK0112 53b6aa0d0f6ee5473d2216f5ee71dd29 91 PIRSF PIRSF006521 3 91 7.3E-33 T 31-10-2018 IPR004542 Translation elongation factor EF1B, beta chain, archaeal GO:0003746|GO:0006414 TK0112 53b6aa0d0f6ee5473d2216f5ee71dd29 91 Gene3D G3DSA:3.30.70.60 1 91 1.2E-35 T 31-10-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 TK0112 53b6aa0d0f6ee5473d2216f5ee71dd29 91 SUPERFAMILY SSF54984 9 91 3.66E-21 T 31-10-2018 IPR036219 Translation elongation factor eEF-1beta-like superfamily Reactome: R-HSA-156842 TK0112 53b6aa0d0f6ee5473d2216f5ee71dd29 91 Pfam PF00736 EF-1 guanine nucleotide exchange domain 9 91 6.5E-21 T 31-10-2018 IPR014038 Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain GO:0003746|GO:0006414 Reactome: R-HSA-156842 TK2038 6b57e8b19d6e444aa440d284f80fee54 189 PIRSF PIRSF006006 1 180 4.5E-84 T 31-10-2018 IPR007501 Protein of unknown function DUF531 TK2038 6b57e8b19d6e444aa440d284f80fee54 189 Pfam PF04407 Protein of unknown function (DUF531) 4 171 3.8E-78 T 31-10-2018 IPR007501 Protein of unknown function DUF531 TK1839 d43a05ebee485d216902498927148535 1110 SMART SM00060 643 714 200.0 T 31-10-2018 IPR003961 Fibronectin type III GO:0005515 TK1839 d43a05ebee485d216902498927148535 1110 SMART SM00060 459 531 190.0 T 31-10-2018 IPR003961 Fibronectin type III GO:0005515 TK1839 d43a05ebee485d216902498927148535 1110 SMART SM00060 552 623 15.0 T 31-10-2018 IPR003961 Fibronectin type III GO:0005515 TK1839 d43a05ebee485d216902498927148535 1110 SMART SM00060 916 987 26.0 T 31-10-2018 IPR003961 Fibronectin type III GO:0005515 TK1839 d43a05ebee485d216902498927148535 1110 SMART SM00060 799 896 12.0 T 31-10-2018 IPR003961 Fibronectin type III GO:0005515 TK1839 d43a05ebee485d216902498927148535 1110 TIGRFAM TIGR02608 delta_60_rpt: delta-60 repeat domain 205 234 1.8E-4 T 31-10-2018 IPR013431 Delta-60 repeat TK1839 d43a05ebee485d216902498927148535 1110 TIGRFAM TIGR02608 delta_60_rpt: delta-60 repeat domain 351 390 0.0024 T 31-10-2018 IPR013431 Delta-60 repeat TK1839 d43a05ebee485d216902498927148535 1110 TIGRFAM TIGR02608 delta_60_rpt: delta-60 repeat domain 299 338 5.9E-4 T 31-10-2018 IPR013431 Delta-60 repeat TK1839 d43a05ebee485d216902498927148535 1110 SUPERFAMILY SSF50998 76 389 6.12E-18 T 31-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily TK1839 d43a05ebee485d216902498927148535 1110 Gene3D G3DSA:2.120.10.30 196 374 3.8E-10 T 31-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like TK0859 b6ae0f9bd7afbf881bccf4046afca64b 145 Gene3D G3DSA:3.40.50.1010 1 125 1.0E-6 T 31-10-2018 TK0859 b6ae0f9bd7afbf881bccf4046afca64b 145 Pfam PF10130 PIN domain 4 121 2.2E-19 T 31-10-2018 IPR002716 PIN domain TK0859 b6ae0f9bd7afbf881bccf4046afca64b 145 SUPERFAMILY SSF88723 3 130 3.92E-15 T 31-10-2018 IPR029060 PIN-like domain superfamily TK0377 79b195c0eee97fbe13c52140b9f92db3 146 Pfam PF05763 Protein of unknown function (DUF835) 36 142 1.0E-24 T 31-10-2018 IPR008553 Domain of unknown function DUF835 TK0150 daf6ba4fae8dd834c16b906277e880b4 134 Pfam PF01597 Glycine cleavage H-protein 13 132 1.7E-50 T 31-10-2018 IPR033753 Glycine cleavage system H-protein/Simiate TK0150 daf6ba4fae8dd834c16b906277e880b4 134 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 10 132 41.908 T 31-10-2018 IPR002930 Glycine cleavage system H-protein GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 TK0150 daf6ba4fae8dd834c16b906277e880b4 134 SUPERFAMILY SSF51230 10 132 9.16E-43 T 31-10-2018 IPR011053 Single hybrid motif TK0150 daf6ba4fae8dd834c16b906277e880b4 134 Gene3D G3DSA:2.40.50.100 2 131 1.3E-52 T 31-10-2018 TK0150 daf6ba4fae8dd834c16b906277e880b4 134 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 11 131 3.8E-47 T 31-10-2018 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 TK0150 daf6ba4fae8dd834c16b906277e880b4 134 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 54 83 - T 31-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 TK2225 425c150e6d9bb3b1023c139d62cef912 307 SMART SM00729 11 227 1.2E-16 T 31-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TK2225 425c150e6d9bb3b1023c139d62cef912 307 Hamap MF_01225_A GTP 3',8-cyclase [moaA]. 2 307 43.474 T 31-10-2018 IPR013485 Molybdenum cofactor biosynthesis protein A, archaea GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823 TK2225 425c150e6d9bb3b1023c139d62cef912 307 Pfam PF13353 4Fe-4S single cluster domain 17 104 4.6E-10 T 31-10-2018 TK2225 425c150e6d9bb3b1023c139d62cef912 307 Gene3D G3DSA:3.20.20.70 1 305 8.6E-79 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TK2225 425c150e6d9bb3b1023c139d62cef912 307 TIGRFAM TIGR02668 moaA_archaeal: probable molybdenum cofactor biosynthesis protein A 2 307 4.8E-128 T 31-10-2018 IPR013485 Molybdenum cofactor biosynthesis protein A, archaea GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823 TK2225 425c150e6d9bb3b1023c139d62cef912 307 Pfam PF04055 Radical SAM superfamily 16 171 1.1E-33 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TK2225 425c150e6d9bb3b1023c139d62cef912 307 SUPERFAMILY SSF102114 3 300 4.84E-69 T 31-10-2018 TK2225 425c150e6d9bb3b1023c139d62cef912 307 Pfam PF06463 Molybdenum Cofactor Synthesis C 179 306 3.2E-22 T 31-10-2018 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TK0997 6918f58517f286a079e6ace23162304a 91 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 7 46 1.0E-11 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 TK0997 6918f58517f286a079e6ace23162304a 91 SUPERFAMILY SSF89447 4 48 3.79E-11 T 31-10-2018 IPR037914 SpoVT-AbrB domain superfamily TK0997 6918f58517f286a079e6ace23162304a 91 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 5 46 2.7E-11 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 TK0997 6918f58517f286a079e6ace23162304a 91 SMART SM00966 6 51 1.3E-12 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 TK0997 6918f58517f286a079e6ace23162304a 91 Gene3D G3DSA:2.10.260.10 3 44 1.1E-9 T 31-10-2018 TK1217 513bf78e1174827d8f50d8bbe581345d 193 TIGRFAM TIGR01957 nuoB_fam: NADH-quinone oxidoreductase, B subunit 18 153 3.6E-45 T 31-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TK1217 513bf78e1174827d8f50d8bbe581345d 193 SUPERFAMILY SSF56770 16 165 2.35E-52 T 31-10-2018 TK1217 513bf78e1174827d8f50d8bbe581345d 193 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 35 146 3.0E-19 T 31-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TK1217 513bf78e1174827d8f50d8bbe581345d 193 Gene3D G3DSA:3.40.50.12280 4 173 4.3E-53 T 31-10-2018 TK1026 96cf11cecdf00fcf535429c5b7592405 252 Gene3D G3DSA:3.20.20.390 3 251 3.0E-100 T 31-10-2018 IPR038597 GGGP/HepGP synthase superfamily TK1026 96cf11cecdf00fcf535429c5b7592405 252 SUPERFAMILY SSF51395 18 238 1.83E-48 T 31-10-2018 TK1026 96cf11cecdf00fcf535429c5b7592405 252 Pfam PF01884 PcrB family 16 237 1.6E-66 T 31-10-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 TK1026 96cf11cecdf00fcf535429c5b7592405 252 TIGRFAM TIGR01769 GGGP: phosphoglycerol geranylgeranyltransferase 21 227 1.2E-82 T 31-10-2018 IPR010946 Geranylgeranylglyceryl phosphate synthase GO:0000287|GO:0005737|GO:0006650|GO:0047294 KEGG: 00564+2.5.1.41|MetaCyc: PWY-6349 TK1026 96cf11cecdf00fcf535429c5b7592405 252 TIGRFAM TIGR01768 GGGP-family: geranylgeranylglyceryl phosphate synthase family protein 20 241 3.3E-78 T 31-10-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 TK1026 96cf11cecdf00fcf535429c5b7592405 252 Hamap MF_00112 Geranylgeranylglyceryl phosphate synthase [pcrB]. 14 246 36.019 T 31-10-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 TK1634 ee6b00f900cc739d3d109e3802c17145 249 Pfam PF01138 3' exoribonuclease family, domain 1 25 154 6.9E-36 T 31-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TK1634 ee6b00f900cc739d3d109e3802c17145 249 TIGRFAM TIGR02065 ECX1: exosome complex exonuclease 1 9 238 1.4E-120 T 31-10-2018 IPR011807 Exosome complex component Rrp41 GO:0000178|GO:0006401|GO:0016896 TK1634 ee6b00f900cc739d3d109e3802c17145 249 Pfam PF03725 3' exoribonuclease family, domain 2 157 222 1.3E-16 T 31-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TK1634 ee6b00f900cc739d3d109e3802c17145 249 Gene3D G3DSA:3.30.230.70 24 249 6.5E-80 T 31-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TK1634 ee6b00f900cc739d3d109e3802c17145 249 SUPERFAMILY SSF55666 155 243 1.96E-26 T 31-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TK1634 ee6b00f900cc739d3d109e3802c17145 249 SUPERFAMILY SSF54211 10 180 5.57E-48 T 31-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TK1634 ee6b00f900cc739d3d109e3802c17145 249 Hamap MF_00591 Exosome complex component Rrp41 [rrp41]. 6 242 61.351 T 31-10-2018 IPR011807 Exosome complex component Rrp41 GO:0000178|GO:0006401|GO:0016896 TK1059 20e69dbebbd11e41950f98a1bfb94633 183 Pfam PF00210 Ferritin-like domain 21 160 1.5E-22 T 31-10-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 TK1059 20e69dbebbd11e41950f98a1bfb94633 183 SUPERFAMILY SSF47240 4 159 2.38E-29 T 31-10-2018 IPR009078 Ferritin-like superfamily TK1059 20e69dbebbd11e41950f98a1bfb94633 183 Gene3D G3DSA:1.20.1260.10 4 160 2.2E-62 T 31-10-2018 IPR012347 Ferritin-like TK1059 20e69dbebbd11e41950f98a1bfb94633 183 PIRSF PIRSF018063 1 168 1.4E-67 T 31-10-2018 IPR014490 DNA-binding protein from starved cells-like TK0432 b574d43456d191fd62bb720455fff026 219 SUPERFAMILY SSF56104 3 215 1.57E-49 T 31-10-2018 TK0432 b574d43456d191fd62bb720455fff026 219 Pfam PF01259 SAICAR synthetase 4 207 2.7E-33 T 31-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TK0432 b574d43456d191fd62bb720455fff026 219 Gene3D G3DSA:3.30.200.20 4 86 7.9E-60 T 31-10-2018 TK0432 b574d43456d191fd62bb720455fff026 219 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 1 219 19.596 T 31-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TK0432 b574d43456d191fd62bb720455fff026 219 ProSitePatterns PS01058 SAICAR synthetase signature 2. 175 183 - T 31-10-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TK0432 b574d43456d191fd62bb720455fff026 219 Gene3D G3DSA:3.30.470.20 87 206 7.9E-60 T 31-10-2018 TK0245 25a4c7d9cc7df29c1126e8c524a7b79f 177 Gene3D G3DSA:3.30.230.40 76 176 1.1E-32 T 31-10-2018 IPR038494 Imidazole glycerol phosphate dehydratase domain superfamily KEGG: 00340+4.2.1.19 TK0245 25a4c7d9cc7df29c1126e8c524a7b79f 177 Gene3D G3DSA:3.30.230.40 1 75 1.5E-20 T 31-10-2018 IPR038494 Imidazole glycerol phosphate dehydratase domain superfamily KEGG: 00340+4.2.1.19 TK0245 25a4c7d9cc7df29c1126e8c524a7b79f 177 SUPERFAMILY SSF54211 2 73 1.9E-16 T 31-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TK0245 25a4c7d9cc7df29c1126e8c524a7b79f 177 ProSitePatterns PS00955 Imidazoleglycerol-phosphate dehydratase signature 2. 141 153 - T 31-10-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 TK0245 25a4c7d9cc7df29c1126e8c524a7b79f 177 Pfam PF00475 Imidazoleglycerol-phosphate dehydratase 22 159 3.0E-36 T 31-10-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 TK0245 25a4c7d9cc7df29c1126e8c524a7b79f 177 SUPERFAMILY SSF54211 75 163 6.83E-26 T 31-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TK0216 5605c43944d0f48a1227b3700f4ff495 197 Hamap MF_01615 Pyridoxal 5'-phosphate synthase subunit PdxT [pdxT]. 4 195 35.388 T 31-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 TK0216 5605c43944d0f48a1227b3700f4ff495 197 TIGRFAM TIGR03800 PLP_synth_Pdx2: pyridoxal 5'-phosphate synthase, glutaminase subunit Pdx2 3 193 1.6E-75 T 31-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 TK0216 5605c43944d0f48a1227b3700f4ff495 197 SUPERFAMILY SSF52317 2 194 6.45E-50 T 31-10-2018 IPR029062 Class I glutamine amidotransferase-like TK0216 5605c43944d0f48a1227b3700f4ff495 197 Gene3D G3DSA:3.40.50.880 1 197 5.7E-69 T 31-10-2018 IPR029062 Class I glutamine amidotransferase-like TK0216 5605c43944d0f48a1227b3700f4ff495 197 Pfam PF01174 SNO glutamine amidotransferase family 6 196 1.5E-57 T 31-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 TK0216 5605c43944d0f48a1227b3700f4ff495 197 PIRSF PIRSF005639 1 197 6.8E-69 T 31-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 TK0216 5605c43944d0f48a1227b3700f4ff495 197 ProSitePatterns PS01236 PdxT/SNO family family signature. 47 57 - T 31-10-2018 IPR021196 PdxT/SNO family, conserved site KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 TK0747 fbdfd2c2694a772b71a349031c690cf9 239 SUPERFAMILY SSF55681 70 234 1.16E-32 T 31-10-2018 TK0747 fbdfd2c2694a772b71a349031c690cf9 239 Gene3D G3DSA:3.30.930.10 72 239 3.6E-32 T 31-10-2018 TK0747 fbdfd2c2694a772b71a349031c690cf9 239 Pfam PF03099 Biotin/lipoate A/B protein ligase family 83 200 5.6E-8 T 31-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 TK0747 fbdfd2c2694a772b71a349031c690cf9 239 SUPERFAMILY SSF46785 4 62 2.32E-10 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TK0747 fbdfd2c2694a772b71a349031c690cf9 239 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 79 237 1.7E-30 T 31-10-2018 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 TK0747 fbdfd2c2694a772b71a349031c690cf9 239 Pfam PF08279 HTH domain 18 59 1.6E-12 T 31-10-2018 IPR013196 Helix-turn-helix, type 11 TK0747 fbdfd2c2694a772b71a349031c690cf9 239 Gene3D G3DSA:1.10.10.10 4 65 2.0E-16 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TK0445 27b8665ce04a87be2c19323264713a56 85 Pfam PF09827 CRISPR associated protein Cas2 1 70 4.0E-21 T 31-10-2018 IPR019199 Virulence-associated protein D / CRISPR associated protein Cas2 TK0445 27b8665ce04a87be2c19323264713a56 85 Gene3D G3DSA:3.30.70.240 1 66 3.3E-30 T 31-10-2018 TK0445 27b8665ce04a87be2c19323264713a56 85 SUPERFAMILY SSF143430 1 80 1.12E-24 T 31-10-2018 TK0445 27b8665ce04a87be2c19323264713a56 85 Hamap MF_01471 CRISPR-associated endoribonuclease Cas2 [cas2]. 1 85 16.34 T 31-10-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 TK0445 27b8665ce04a87be2c19323264713a56 85 TIGRFAM TIGR01573 cas2: CRISPR-associated endonuclease Cas2 1 73 8.6E-13 T 31-10-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 TK2255 ac867ea460a0e8311bb51049590eea2c 440 Gene3D G3DSA:3.40.50.1000 6 185 1.4E-32 T 31-10-2018 IPR023214 HAD superfamily TK2255 ac867ea460a0e8311bb51049590eea2c 440 SUPERFAMILY SSF56784 2 214 2.63E-38 T 31-10-2018 IPR036412 HAD-like superfamily TK2255 ac867ea460a0e8311bb51049590eea2c 440 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 90 177 3.8E-7 T 31-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TK2255 ac867ea460a0e8311bb51049590eea2c 440 Gene3D G3DSA:1.10.150.240 18 80 1.4E-32 T 31-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 TK2255 ac867ea460a0e8311bb51049590eea2c 440 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 180 3.0E-25 T 31-10-2018 TK2255 ac867ea460a0e8311bb51049590eea2c 440 SUPERFAMILY SSF53448 221 423 9.72E-33 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TK2255 ac867ea460a0e8311bb51049590eea2c 440 Gene3D G3DSA:3.90.550.10 217 436 9.8E-46 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TK2255 ac867ea460a0e8311bb51049590eea2c 440 Pfam PF00535 Glycosyl transferase family 2 221 343 2.5E-25 T 31-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TK2255 ac867ea460a0e8311bb51049590eea2c 440 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 145 165 1.5E-6 T 31-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TK2255 ac867ea460a0e8311bb51049590eea2c 440 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 94 107 1.5E-6 T 31-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TK2255 ac867ea460a0e8311bb51049590eea2c 440 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 3 14 1.5E-6 T 31-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TK1920 a114b3eb2a4dcf8f83cc5d6cfbd22934 130 Gene3D G3DSA:1.10.10.10 2 51 6.6E-6 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TK1920 a114b3eb2a4dcf8f83cc5d6cfbd22934 130 SUPERFAMILY SSF88659 9 48 1.5E-6 T 31-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like TK0248 c6d9f6e613f8923dbf015dcb1854f63e 252 TIGRFAM TIGR00735 hisF: imidazoleglycerol phosphate synthase, cyclase subunit 1 249 7.2E-109 T 31-10-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 TK0248 c6d9f6e613f8923dbf015dcb1854f63e 252 SUPERFAMILY SSF51366 1 249 3.77E-83 T 31-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 TK0248 c6d9f6e613f8923dbf015dcb1854f63e 252 Gene3D G3DSA:3.20.20.70 1 252 4.2E-106 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TK0248 c6d9f6e613f8923dbf015dcb1854f63e 252 Pfam PF00977 Histidine biosynthesis protein 5 233 6.0E-88 T 31-10-2018 IPR006062 Histidine biosynthesis GO:0000105 TK0248 c6d9f6e613f8923dbf015dcb1854f63e 252 Hamap MF_01013 Imidazole glycerol phosphate synthase subunit HisF [hisF]. 1 249 47.97 T 31-10-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 TK1309 e771fa4614b4391c87039690e6359d83 67 SMART SM00746 7 45 6.6E-12 T 31-10-2018 IPR011017 TRASH domain TK1309 e771fa4614b4391c87039690e6359d83 67 SUPERFAMILY SSF57716 6 56 6.41E-21 T 31-10-2018 TK1309 e771fa4614b4391c87039690e6359d83 67 Pfam PF01246 Ribosomal protein L24e 3 60 2.9E-25 T 31-10-2018 IPR000988 Ribosomal protein L24e-related TK1309 e771fa4614b4391c87039690e6359d83 67 ProSitePatterns PS01073 Ribosomal protein L24e signature. 9 26 - T 31-10-2018 IPR023442 Ribosomal protein L24e, conserved site TK1309 e771fa4614b4391c87039690e6359d83 67 Hamap MF_00773 50S ribosomal protein L24e [rpl24e]. 2 55 27.306 T 31-10-2018 IPR023438 Ribosomal protein L24e GO:0003735|GO:0005622|GO:0005840|GO:0006412 TK1309 e771fa4614b4391c87039690e6359d83 67 Gene3D G3DSA:2.30.170.20 2 66 2.5E-27 T 31-10-2018 IPR038630 Ribosomal protein L24e/L24 superfamily TK1466 deb531797f620a4f39927b63c07fe14b 439 SUPERFAMILY SSF53187 2 436 1.04E-59 T 31-10-2018 TK1466 deb531797f620a4f39927b63c07fe14b 439 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 101 138 - T 31-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 TK1466 deb531797f620a4f39927b63c07fe14b 439 Gene3D G3DSA:3.40.630.10 1 208 1.2E-51 T 31-10-2018 TK1466 deb531797f620a4f39927b63c07fe14b 439 Gene3D G3DSA:3.40.630.10 353 425 5.1E-17 T 31-10-2018 TK1466 deb531797f620a4f39927b63c07fe14b 439 Gene3D G3DSA:3.30.70.360 313 352 5.1E-17 T 31-10-2018 TK1466 deb531797f620a4f39927b63c07fe14b 439 Pfam PF01546 Peptidase family M20/M25/M40 67 434 4.0E-36 T 31-10-2018 IPR002933 Peptidase M20 GO:0016787 TK1466 deb531797f620a4f39927b63c07fe14b 439 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 66 75 - T 31-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 TK1060 3a643ab1ff18875cc3db905ba37501ec 100 SUPERFAMILY SSF47240 6 86 1.3E-19 T 31-10-2018 IPR009078 Ferritin-like superfamily TK1060 3a643ab1ff18875cc3db905ba37501ec 100 Gene3D G3DSA:1.20.1260.10 3 75 1.5E-10 T 31-10-2018 IPR012347 Ferritin-like TK1060 3a643ab1ff18875cc3db905ba37501ec 100 Pfam PF02915 Rubrerythrin 24 92 7.5E-8 T 31-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 TK1450 17d10c2b48663ebd89a4042c6335ca1d 220 ProDom PD016938 P COMPONENT RIBONUCLEASE RNASE HYDROLASE PROCESSING TRNA SUBUNIT SIMILAR P/RNASE 117 209 8.0E-49 T 31-10-2018 TK1450 17d10c2b48663ebd89a4042c6335ca1d 220 Hamap MF_00756 Ribonuclease P protein component 3 [rnp3]. 11 220 22.595 T 31-10-2018 IPR023539 Ribonuclease P, protein component 3, archaeal GO:0001682|GO:0004526 TK1450 17d10c2b48663ebd89a4042c6335ca1d 220 SUPERFAMILY SSF89550 13 216 5.89E-33 T 31-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 TK1450 17d10c2b48663ebd89a4042c6335ca1d 220 Gene3D G3DSA:3.20.20.140 1 220 2.6E-116 T 31-10-2018 TK1450 17d10c2b48663ebd89a4042c6335ca1d 220 Pfam PF01876 RNase P subunit p30 21 210 1.2E-36 T 31-10-2018 IPR002738 RNase P subunit p30 GO:0004540|GO:0008033 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 TK1411 df80f4a7d5da9221dd5219732655d3de 133 SMART SM00493 20 90 2.8E-5 T 31-10-2018 IPR006171 TOPRIM domain TK1411 df80f4a7d5da9221dd5219732655d3de 133 Pfam PF01751 Toprim domain 51 86 2.7E-5 T 31-10-2018 IPR006171 TOPRIM domain TK1411 df80f4a7d5da9221dd5219732655d3de 133 Gene3D G3DSA:3.40.1360.10 3 117 3.7E-21 T 31-10-2018 TK1411 df80f4a7d5da9221dd5219732655d3de 133 Hamap MF_01095 UPF0292 protein . 3 123 31.848 T 31-10-2018 IPR022972 Uncharacterised protein family UPF0292 TK1411 df80f4a7d5da9221dd5219732655d3de 133 SUPERFAMILY SSF110455 19 88 1.73E-5 T 31-10-2018 TK1852 75f4c9e72ef2a9b804a400eca1e6066e 351 Gene3D G3DSA:1.20.81.30 167 283 4.6E-12 T 31-10-2018 TK1852 75f4c9e72ef2a9b804a400eca1e6066e 351 Pfam PF00482 Type II secretion system (T2SS), protein F 182 307 3.8E-23 T 31-10-2018 IPR018076 Type II secretion system F domain TK0195 54258807878e0e2b8453ed4f1a4aa7f1 347 Pfam PF05763 Protein of unknown function (DUF835) 225 346 1.3E-34 T 31-10-2018 IPR008553 Domain of unknown function DUF835 TK2301 5a366e3a52528070a078c6f4be6765b9 239 Gene3D G3DSA:3.40.50.1000 4 223 1.0E-72 T 31-10-2018 IPR023214 HAD superfamily TK2301 5a366e3a52528070a078c6f4be6765b9 239 SUPERFAMILY SSF56784 1 228 4.6E-42 T 31-10-2018 IPR036412 HAD-like superfamily TK2301 5a366e3a52528070a078c6f4be6765b9 239 TIGRFAM TIGR01487 Pglycolate_arch: phosphoglycolate phosphatase, TA0175-type 3 222 2.7E-76 T 31-10-2018 TK2301 5a366e3a52528070a078c6f4be6765b9 239 Gene3D G3DSA:3.90.1070.10 86 153 1.0E-72 T 31-10-2018 TK2301 5a366e3a52528070a078c6f4be6765b9 239 TIGRFAM TIGR01482 SPP-subfamily: sucrose-phosphate phosphatase subfamily 6 232 1.6E-73 T 31-10-2018 TK2301 5a366e3a52528070a078c6f4be6765b9 239 Hamap MF_01419 Phosphoglycolate phosphatase. 3 229 32.028 T 31-10-2018 IPR006382 Phosphoglycolate phosphatase GO:0000287|GO:0008967|GO:0016311 KEGG: 00630+3.1.3.18|MetaCyc: PWY-181 TK2301 5a366e3a52528070a078c6f4be6765b9 239 Pfam PF08282 haloacid dehalogenase-like hydrolase 139 223 6.4E-19 T 31-10-2018 TK2301 5a366e3a52528070a078c6f4be6765b9 239 Pfam PF08282 haloacid dehalogenase-like hydrolase 6 88 5.3E-7 T 31-10-2018 TK0063 1721fd3db701bbfbf01b72f40d284cb7 182 Gene3D G3DSA:3.30.460.10 81 169 1.8E-16 T 31-10-2018 TK0063 1721fd3db701bbfbf01b72f40d284cb7 182 Gene3D G3DSA:1.10.10.10 9 75 2.4E-7 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TK0063 1721fd3db701bbfbf01b72f40d284cb7 182 SUPERFAMILY SSF81301 80 177 2.36E-17 T 31-10-2018 TK0063 1721fd3db701bbfbf01b72f40d284cb7 182 Pfam PF01022 Bacterial regulatory protein, arsR family 12 58 1.2E-4 T 31-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TK0063 1721fd3db701bbfbf01b72f40d284cb7 182 SUPERFAMILY SSF46785 13 79 8.19E-9 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TK0063 1721fd3db701bbfbf01b72f40d284cb7 182 Pfam PF01909 Nucleotidyltransferase domain 95 155 1.1E-9 T 31-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 TK1821 c4efe2ffc8d96e458cd67cb37cba9a2f 323 SUPERFAMILY SSF52402 25 257 2.43E-54 T 31-10-2018 TK1821 c4efe2ffc8d96e458cd67cb37cba9a2f 323 PIRSF PIRSF004976 1 317 3.3E-112 T 31-10-2018 IPR035107 tRNA thiolation protein, TtcA/Ctu1 type GO:0008033 Reactome: R-HSA-6782315 TK1821 c4efe2ffc8d96e458cd67cb37cba9a2f 323 TIGRFAM TIGR00269 TIGR00269: TIGR00269 family protein 204 305 1.1E-37 T 31-10-2018 IPR000541 Cytoplasmic tRNA 2-thiolation protein 1 GO:0000049|GO:0002098|GO:0034227 Reactome: R-HSA-6782315 TK1821 c4efe2ffc8d96e458cd67cb37cba9a2f 323 Gene3D G3DSA:3.40.50.620 1 319 1.2E-87 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TK1821 c4efe2ffc8d96e458cd67cb37cba9a2f 323 Pfam PF01171 PP-loop family 50 228 1.6E-14 T 31-10-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 TK1821 c4efe2ffc8d96e458cd67cb37cba9a2f 323 ProSitePatterns PS01263 Uncharacterized protein family UPF0021 signature. 22 59 - T 31-10-2018 IPR020554 Uncharacterised protein family UPF0021, conserved site TK0256 63bb4df92a386df41fded460af0c9d64 208 Pfam PF00697 N-(5'phosphoribosyl)anthranilate (PRA) isomerase 5 202 3.7E-31 T 31-10-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 TK0256 63bb4df92a386df41fded460af0c9d64 208 Hamap MF_00135 N-(5'-phosphoribosyl)anthranilate isomerase [trpF]. 3 208 29.027 T 31-10-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 TK0256 63bb4df92a386df41fded460af0c9d64 208 Gene3D G3DSA:3.20.20.70 1 208 5.4E-78 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TK0256 63bb4df92a386df41fded460af0c9d64 208 SUPERFAMILY SSF51366 4 205 1.08E-38 T 31-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 TK1173 13dfdc6fd1c220140aaf3a59bd9d5722 264 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 34 263 1.7E-87 T 31-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 TK1173 13dfdc6fd1c220140aaf3a59bd9d5722 264 Pfam PF01255 Putative undecaprenyl diphosphate synthase 41 263 8.5E-84 T 31-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 TK1173 13dfdc6fd1c220140aaf3a59bd9d5722 264 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 209 226 - T 31-10-2018 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199|Reactome: R-HSA-4755609 TK1173 13dfdc6fd1c220140aaf3a59bd9d5722 264 Gene3D G3DSA:3.40.1180.10 18 264 3.9E-104 T 31-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 TK1173 13dfdc6fd1c220140aaf3a59bd9d5722 264 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 34 264 40.133 T 31-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 TK1173 13dfdc6fd1c220140aaf3a59bd9d5722 264 SUPERFAMILY SSF64005 31 259 3.27E-88 T 31-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 TK0153 fcd4d9b641d0386032c594003e8e5007 308 Gene3D G3DSA:1.10.4200.10 25 293 1.0E-60 T 31-10-2018 TK0153 fcd4d9b641d0386032c594003e8e5007 308 Pfam PF01874 ATP:dephospho-CoA triphosphoribosyl transferase 9 285 2.1E-53 T 31-10-2018 IPR002736 Triphosphoribosyl-dephospho-CoA protein GO:0005524|GO:0016310|GO:0046917 MetaCyc: PWY-5796 TK0650 ed13e6689c2b5ae19871257aaa94c245 174 Gene3D G3DSA:1.20.1260.10 12 161 2.4E-49 T 31-10-2018 IPR012347 Ferritin-like TK0650 ed13e6689c2b5ae19871257aaa94c245 174 Pfam PF02915 Rubrerythrin 22 157 3.3E-32 T 31-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 TK0650 ed13e6689c2b5ae19871257aaa94c245 174 SUPERFAMILY SSF47240 12 165 4.55E-31 T 31-10-2018 IPR009078 Ferritin-like superfamily TK1630 fafbc6ccbcfb543a6ef624b2c710427b 234 TIGRFAM TIGR00310 ZPR1_znf: ZPR1 zinc finger domain 27 209 3.9E-61 T 31-10-2018 IPR004457 Zinc finger, ZPR1-type GO:0008270 TK1630 fafbc6ccbcfb543a6ef624b2c710427b 234 TIGRFAM TIGR00340 zpr1_rel: zinc finger protein ZPR1 homolog 28 193 6.5E-69 T 31-10-2018 IPR004470 Zinc finger, ZPR1-type, subgroup GO:0008270 TK1630 fafbc6ccbcfb543a6ef624b2c710427b 234 Gene3D G3DSA:2.60.120.1040 75 201 3.6E-22 T 31-10-2018 TK1630 fafbc6ccbcfb543a6ef624b2c710427b 234 Pfam PF03367 ZPR1 zinc-finger domain 27 183 1.8E-38 T 31-10-2018 IPR004457 Zinc finger, ZPR1-type GO:0008270 TK1630 fafbc6ccbcfb543a6ef624b2c710427b 234 Gene3D G3DSA:2.20.25.420 19 71 4.0E-7 T 31-10-2018 TK1630 fafbc6ccbcfb543a6ef624b2c710427b 234 SMART SM00709 26 186 1.1E-79 T 31-10-2018 IPR004457 Zinc finger, ZPR1-type GO:0008270 TK1639 aed9804824d0392ef716d09eff5560a4 155 SUPERFAMILY SSF54197 1 125 4.96E-39 T 31-10-2018 IPR036265 HIT-like superfamily TK1639 aed9804824d0392ef716d09eff5560a4 155 Pfam PF01230 HIT domain 11 100 9.2E-24 T 31-10-2018 IPR001310 Histidine triad (HIT) protein TK1639 aed9804824d0392ef716d09eff5560a4 155 Gene3D G3DSA:3.30.428.10 1 138 1.3E-39 T 31-10-2018 IPR036265 HIT-like superfamily TK1639 aed9804824d0392ef716d09eff5560a4 155 ProSitePatterns PS00892 HIT domain signature. 81 99 - T 31-10-2018 IPR019808 Histidine triad, conserved site TK1147 bc98a152564c503652307c921bd13220 710 SUPERFAMILY SSF52980 19 128 2.09E-5 T 31-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 TK1147 bc98a152564c503652307c921bd13220 710 Pfam PF04471 Restriction endonuclease 14 123 1.1E-11 T 31-10-2018 IPR007560 Restriction endonuclease type IV, Mrr GO:0003677|GO:0004519|GO:0009307 TK0931 20d6ae13fbb91f0bf70d6d12979df73e 391 Pfam PF07282 Putative transposase DNA-binding domain 290 357 2.0E-24 T 31-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal TK0931 20d6ae13fbb91f0bf70d6d12979df73e 391 Pfam PF12323 Helix-turn-helix domain 2 38 3.6E-10 T 31-10-2018 IPR021027 Transposase, putative, helix-turn-helix domain TK0931 20d6ae13fbb91f0bf70d6d12979df73e 391 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 240 315 1.2E-16 T 31-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal TK0931 20d6ae13fbb91f0bf70d6d12979df73e 391 Pfam PF01385 Probable transposase 165 272 2.2E-24 T 31-10-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 TK0643 2fcda2c5c5e189dbceb8505d0ce80707 117 Hamap MF_00307 Prefoldin subunit beta [pfdB]. 1 117 51.117 T 31-10-2018 IPR012713 Prefoldin subunit beta GO:0006457|GO:0016272|GO:0051082 TK0643 2fcda2c5c5e189dbceb8505d0ce80707 117 Gene3D G3DSA:1.10.287.370 1 117 9.4E-42 T 31-10-2018 IPR009053 Prefoldin TK0643 2fcda2c5c5e189dbceb8505d0ce80707 117 Pfam PF01920 Prefoldin subunit 9 111 4.9E-26 T 31-10-2018 IPR002777 Prefoldin beta-like GO:0006457|GO:0016272|GO:0051082 Reactome: R-HSA-389957 TK0643 2fcda2c5c5e189dbceb8505d0ce80707 117 TIGRFAM TIGR02338 gimC_beta: prefoldin, beta subunit 4 112 1.8E-40 T 31-10-2018 IPR012713 Prefoldin subunit beta GO:0006457|GO:0016272|GO:0051082 TK0643 2fcda2c5c5e189dbceb8505d0ce80707 117 SUPERFAMILY SSF46579 6 110 7.32E-25 T 31-10-2018 TK1772 295ea5108f4d59884a9065ecc57de7d1 300 Gene3D G3DSA:1.10.3720.10 56 297 3.2E-58 T 31-10-2018 IPR035906 MetI-like superfamily TK1772 295ea5108f4d59884a9065ecc57de7d1 300 SUPERFAMILY SSF160964 8 52 1.44E-7 T 31-10-2018 TK1772 295ea5108f4d59884a9065ecc57de7d1 300 SUPERFAMILY SSF161098 60 285 4.32E-50 T 31-10-2018 IPR035906 MetI-like superfamily TK1772 295ea5108f4d59884a9065ecc57de7d1 300 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 94 286 5.3E-16 T 31-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TK0886 233c5d1c83b51d031eca12342a21e1d5 573 Pfam PF00654 Voltage gated chloride channel 70 412 1.5E-88 T 31-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 TK0886 233c5d1c83b51d031eca12342a21e1d5 573 Gene3D G3DSA:1.10.3080.10 13 436 3.1E-96 T 31-10-2018 IPR014743 Chloride channel, core Reactome: R-HSA-2672351 TK0886 233c5d1c83b51d031eca12342a21e1d5 573 PRINTS PR00762 Chloride channel signature 362 378 1.7E-17 T 31-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 TK0886 233c5d1c83b51d031eca12342a21e1d5 573 PRINTS PR00762 Chloride channel signature 82 99 1.7E-17 T 31-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 TK0886 233c5d1c83b51d031eca12342a21e1d5 573 PRINTS PR00762 Chloride channel signature 162 181 1.7E-17 T 31-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 TK0886 233c5d1c83b51d031eca12342a21e1d5 573 PRINTS PR00762 Chloride channel signature 380 399 1.7E-17 T 31-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 TK0886 233c5d1c83b51d031eca12342a21e1d5 573 PRINTS PR00762 Chloride channel signature 327 347 1.7E-17 T 31-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 TK0886 233c5d1c83b51d031eca12342a21e1d5 573 Pfam PF00571 CBS domain 445 498 6.9E-12 T 31-10-2018 IPR000644 CBS domain TK0886 233c5d1c83b51d031eca12342a21e1d5 573 Pfam PF00571 CBS domain 507 562 8.4E-7 T 31-10-2018 IPR000644 CBS domain TK0886 233c5d1c83b51d031eca12342a21e1d5 573 SMART SM00116 514 564 0.0077 T 31-10-2018 IPR000644 CBS domain TK0886 233c5d1c83b51d031eca12342a21e1d5 573 SMART SM00116 452 500 9.7E-7 T 31-10-2018 IPR000644 CBS domain TK0886 233c5d1c83b51d031eca12342a21e1d5 573 Gene3D G3DSA:3.10.580.10 438 565 2.5E-23 T 31-10-2018 TK0886 233c5d1c83b51d031eca12342a21e1d5 573 SUPERFAMILY SSF54631 439 564 1.07E-26 T 31-10-2018 TK0886 233c5d1c83b51d031eca12342a21e1d5 573 SUPERFAMILY SSF81340 10 432 4.58E-101 T 31-10-2018 IPR014743 Chloride channel, core Reactome: R-HSA-2672351 TK1012 251f250fcef68ad77599ef0159affe43 203 Pfam PF07690 Major Facilitator Superfamily 27 194 1.7E-35 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TK1012 251f250fcef68ad77599ef0159affe43 203 SUPERFAMILY SSF103473 13 197 3.66E-44 T 31-10-2018 IPR036259 MFS transporter superfamily TK1012 251f250fcef68ad77599ef0159affe43 203 Gene3D G3DSA:1.20.1720.10 19 202 6.4E-46 T 31-10-2018 TK0461 8e3c76c60baa778d2079ca0c9072dd31 210 TIGRFAM TIGR02593 CRISPR_cas5: CRISPR-associated protein Cas5 1 43 9.6E-17 T 31-10-2018 IPR013422 CRISPR-associated protein Cas5, N-terminal TK0461 8e3c76c60baa778d2079ca0c9072dd31 210 TIGRFAM TIGR01895 cas_Cas5t: CRISPR-associated protein Cas5, subtype I-B/TNEAP 1 198 6.0E-54 T 31-10-2018 IPR013337 CRISPR-associated protein Cas5, Tneap type TK0461 8e3c76c60baa778d2079ca0c9072dd31 210 Pfam PF09704 CRISPR-associated protein (Cas_Cas5) 2 43 2.6E-5 T 31-10-2018 IPR021124 CRISPR-associated protein, Cas5 GO:0043571 TK0302 385970c3e540713395540d350ad2d81e 180 Pfam PF01885 RNA 2'-phosphotransferase, Tpt1 / KptA family 5 167 2.0E-33 T 31-10-2018 IPR002745 Phosphotransferase KptA/Tpt1 GO:0006388|GO:0016772 TK0302 385970c3e540713395540d350ad2d81e 180 Hamap MF_00299 Probable RNA 2'-phosphotransferase [kptA]. 4 176 34.16 T 31-10-2018 IPR022928 RNA 2'-phosphotransferase KptA, putative GO:0016773 TK0302 385970c3e540713395540d350ad2d81e 180 Gene3D G3DSA:3.20.170.30 95 180 1.5E-30 T 31-10-2018 TK0302 385970c3e540713395540d350ad2d81e 180 Gene3D G3DSA:1.10.10.970 4 75 1.0E-23 T 31-10-2018 TK0302 385970c3e540713395540d350ad2d81e 180 SUPERFAMILY SSF56399 7 178 4.82E-58 T 31-10-2018 TK1761 9724b32d04e4906f8ce033d76db1c1c8 484 Pfam PF00232 Glycosyl hydrolase family 1 3 89 1.0E-7 T 31-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TK1761 9724b32d04e4906f8ce033d76db1c1c8 484 Pfam PF00232 Glycosyl hydrolase family 1 122 480 1.1E-54 T 31-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TK1761 9724b32d04e4906f8ce033d76db1c1c8 484 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 395 403 - T 31-10-2018 IPR018120 Glycoside hydrolase family 1, active site TK1761 9724b32d04e4906f8ce033d76db1c1c8 484 PRINTS PR00131 Glycosyl hydrolase family 1 signature 318 332 2.8E-17 T 31-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TK1761 9724b32d04e4906f8ce033d76db1c1c8 484 PRINTS PR00131 Glycosyl hydrolase family 1 signature 428 445 2.8E-17 T 31-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TK1761 9724b32d04e4906f8ce033d76db1c1c8 484 PRINTS PR00131 Glycosyl hydrolase family 1 signature 395 403 2.8E-17 T 31-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TK1761 9724b32d04e4906f8ce033d76db1c1c8 484 PRINTS PR00131 Glycosyl hydrolase family 1 signature 452 464 2.8E-17 T 31-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TK1761 9724b32d04e4906f8ce033d76db1c1c8 484 PRINTS PR00131 Glycosyl hydrolase family 1 signature 407 418 2.8E-17 T 31-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 TK1761 9724b32d04e4906f8ce033d76db1c1c8 484 SUPERFAMILY SSF51445 3 481 2.27E-122 T 31-10-2018 IPR017853 Glycoside hydrolase superfamily TK1761 9724b32d04e4906f8ce033d76db1c1c8 484 Gene3D G3DSA:3.20.20.80 1 483 4.1E-137 T 31-10-2018 TK2129 ec80e2daaa866d021616a1a57c52b5a7 226 SUPERFAMILY SSF51351 3 221 2.09E-46 T 31-10-2018 IPR035990 Triosephosphate isomerase superfamily GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TK2129 ec80e2daaa866d021616a1a57c52b5a7 226 ProSitePatterns PS00171 Triosephosphate isomerase active site. 142 152 - T 31-10-2018 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TK2129 ec80e2daaa866d021616a1a57c52b5a7 226 Gene3D G3DSA:3.20.20.70 1 225 2.3E-93 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TK2129 ec80e2daaa866d021616a1a57c52b5a7 226 Pfam PF00121 Triosephosphate isomerase 8 114 2.3E-10 T 31-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TK2129 ec80e2daaa866d021616a1a57c52b5a7 226 Hamap MF_00147_A Triosephosphate isomerase [tpiA]. 6 225 43.573 T 31-10-2018 IPR022891 Triosephosphate isomerase, archaeal GO:0004807|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003 TK2129 ec80e2daaa866d021616a1a57c52b5a7 226 Pfam PF05690 Thiazole biosynthesis protein ThiG 166 216 6.3E-6 T 31-10-2018 IPR033983 Thiazole synthase ThiG KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 TK2129 ec80e2daaa866d021616a1a57c52b5a7 226 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 8 212 1.1E-63 T 31-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TK2099 77a32b816a40860288859ecddede4379 177 PIRSF PIRSF019311 2 177 2.7E-90 T 31-10-2018 IPR016756 Metal-dependent hydrolase, membrane-bound predicted TK2099 77a32b816a40860288859ecddede4379 177 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 21 171 1.2E-15 T 31-10-2018 IPR007404 LexA-binding, inner membrane-associated putative hydrolase TK2229 869ba131c9de01ca144cd64b71e6eb27 74 SMART SM00966 4 49 1.0E-12 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 TK2229 869ba131c9de01ca144cd64b71e6eb27 74 SUPERFAMILY SSF89447 1 45 1.41E-12 T 31-10-2018 IPR037914 SpoVT-AbrB domain superfamily TK2229 869ba131c9de01ca144cd64b71e6eb27 74 Gene3D G3DSA:2.10.260.10 2 42 1.6E-15 T 31-10-2018 TK2229 869ba131c9de01ca144cd64b71e6eb27 74 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 3 44 7.7E-14 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 TK2229 869ba131c9de01ca144cd64b71e6eb27 74 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 5 44 1.3E-13 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 TK1167 d125b4999e96755d6400abdfbba09195 94 SUPERFAMILY SSF55257 2 94 3.79E-24 T 31-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TK1167 d125b4999e96755d6400abdfbba09195 94 Hamap MF_00261 DNA-directed RNA polymerase subunit L [rpoL]. 1 89 20.345 T 31-10-2018 IPR022905 DNA-directed RNA polymerase subunit L (Rpo11) GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TK1167 d125b4999e96755d6400abdfbba09195 94 Gene3D G3DSA:3.30.1360.10 1 94 2.5E-35 T 31-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TK1167 d125b4999e96755d6400abdfbba09195 94 ProSitePatterns PS01154 RNA polymerases L / 13 to 16 Kd subunits signature. 17 48 - T 31-10-2018 IPR008193 DNA-directed RNA polymerase Rpb11, 13-16kDa subunit, conserved site GO:0003677|GO:0003899|GO:0006351 TK1167 d125b4999e96755d6400abdfbba09195 94 Pfam PF13656 RNA polymerase Rpb3/Rpb11 dimerisation domain 13 86 1.6E-20 T 31-10-2018 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 TK0777 d9c0f3bfb169f8e77daa3be0416b93fa 282 SUPERFAMILY SSF56349 6 270 2.91E-60 T 31-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 TK0777 d9c0f3bfb169f8e77daa3be0416b93fa 282 Hamap MF_02055 Tyrosine recombinase XerA [xerA]. 4 274 42.417 T 31-10-2018 IPR033686 Tyrosine recombinase XerA TK0777 d9c0f3bfb169f8e77daa3be0416b93fa 282 Gene3D G3DSA:1.10.443.10 91 282 3.2E-77 T 31-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 TK0777 d9c0f3bfb169f8e77daa3be0416b93fa 282 Pfam PF00589 Phage integrase family 99 262 1.1E-49 T 31-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 TK0777 d9c0f3bfb169f8e77daa3be0416b93fa 282 Gene3D G3DSA:1.10.150.130 2 90 1.7E-21 T 31-10-2018 IPR010998 Integrase/recombinase, N-terminal TK0777 d9c0f3bfb169f8e77daa3be0416b93fa 282 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 8 77 5.6E-10 T 31-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 TK0632 a89576c1b48fd2d61a63905251d903f6 120 Gene3D G3DSA:3.40.50.2300 1 120 5.4E-41 T 31-10-2018 TK0632 a89576c1b48fd2d61a63905251d903f6 120 SUPERFAMILY SSF52172 1 119 3.27E-40 T 31-10-2018 IPR011006 CheY-like superfamily TK0632 a89576c1b48fd2d61a63905251d903f6 120 SMART SM00448 2 114 1.9E-38 T 31-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TK0632 a89576c1b48fd2d61a63905251d903f6 120 Pfam PF00072 Response regulator receiver domain 4 114 6.4E-33 T 31-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TK0711 c6bdd25d68d9db8167e015e261ff62b3 169 ProSitePatterns PS01318 TsaA-like domain signature. 89 100 - T 31-10-2018 IPR023368 Uncharacterised protein family UPF0066, conserved site TK0711 c6bdd25d68d9db8167e015e261ff62b3 169 TIGRFAM TIGR00104 tRNA_TsaA: tRNA-Thr(GGU) m(6)t(6)A37 methyltransferase TsaA 11 142 7.4E-43 T 31-10-2018 IPR023370 YaeB-like, N-terminal domain TK0711 c6bdd25d68d9db8167e015e261ff62b3 169 Gene3D G3DSA:2.40.30.70 12 157 2.2E-47 T 31-10-2018 IPR036414 YaeB, N-terminal domain superfamily TK0711 c6bdd25d68d9db8167e015e261ff62b3 169 SUPERFAMILY SSF118196 10 159 7.59E-55 T 31-10-2018 IPR036413 YaeB-like superfamily TK0711 c6bdd25d68d9db8167e015e261ff62b3 169 Pfam PF01980 Uncharacterised protein family UPF0066 29 141 1.4E-38 T 31-10-2018 IPR023370 YaeB-like, N-terminal domain TK1496 e15ef87ce3bdc81e002fa2e7a119a468 201 ProSitePatterns PS00963 Ribosomal protein S2 signature 2. 111 135 - T 31-10-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 TK1496 e15ef87ce3bdc81e002fa2e7a119a468 201 TIGRFAM TIGR01012 uS2_euk_arch: ribosomal protein uS2 3 197 2.3E-99 T 31-10-2018 IPR005707 Ribosomal protein S2, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1496 e15ef87ce3bdc81e002fa2e7a119a468 201 PRINTS PR00395 Ribosomal protein S2 signature 8 26 2.9E-31 T 31-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TK1496 e15ef87ce3bdc81e002fa2e7a119a468 201 PRINTS PR00395 Ribosomal protein S2 signature 128 139 2.9E-31 T 31-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TK1496 e15ef87ce3bdc81e002fa2e7a119a468 201 PRINTS PR00395 Ribosomal protein S2 signature 86 103 2.9E-31 T 31-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TK1496 e15ef87ce3bdc81e002fa2e7a119a468 201 PRINTS PR00395 Ribosomal protein S2 signature 149 163 2.9E-31 T 31-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TK1496 e15ef87ce3bdc81e002fa2e7a119a468 201 PRINTS PR00395 Ribosomal protein S2 signature 111 128 2.9E-31 T 31-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TK1496 e15ef87ce3bdc81e002fa2e7a119a468 201 PRINTS PR00395 Ribosomal protein S2 signature 38 47 2.9E-31 T 31-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TK1496 e15ef87ce3bdc81e002fa2e7a119a468 201 Hamap MF_00291_A 30S ribosomal protein S2 [rpsB]. 1 198 48.724 T 31-10-2018 IPR023454 Ribosomal protein S2, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 TK1496 e15ef87ce3bdc81e002fa2e7a119a468 201 Pfam PF00318 Ribosomal protein S2 110 174 7.2E-14 T 31-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TK1496 e15ef87ce3bdc81e002fa2e7a119a468 201 Pfam PF00318 Ribosomal protein S2 12 104 7.5E-11 T 31-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TK1496 e15ef87ce3bdc81e002fa2e7a119a468 201 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 8 19 - T 31-10-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 TK1496 e15ef87ce3bdc81e002fa2e7a119a468 201 SUPERFAMILY SSF52313 4 191 1.44E-62 T 31-10-2018 IPR023591 Ribosomal protein S2, flavodoxin-like domain superfamily TK1496 e15ef87ce3bdc81e002fa2e7a119a468 201 Gene3D G3DSA:3.40.50.10490 7 201 3.1E-72 T 31-10-2018 TK1983 caef679720d75d4ff35bb694ef88d984 394 Gene3D G3DSA:3.40.50.920 253 391 7.9E-40 T 31-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TK1983 caef679720d75d4ff35bb694ef88d984 394 SUPERFAMILY SSF52518 5 251 3.14E-70 T 31-10-2018 IPR029061 Thiamin diphosphate-binding fold TK1983 caef679720d75d4ff35bb694ef88d984 394 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 262 365 7.3E-29 T 31-10-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II TK1983 caef679720d75d4ff35bb694ef88d984 394 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 16 240 2.1E-81 T 31-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 TK1983 caef679720d75d4ff35bb694ef88d984 394 SUPERFAMILY SSF52922 254 369 2.49E-32 T 31-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TK1983 caef679720d75d4ff35bb694ef88d984 394 Gene3D G3DSA:3.40.50.970 3 252 1.3E-104 T 31-10-2018 TK2119 1a9dc85d23eb9f0be0871985d26d1700 171 Pfam PF01864 CDP-archaeol synthase 7 171 3.3E-60 T 31-10-2018 IPR032690 CDP-archaeol synthase KEGG: 00564+2.7.7.67|MetaCyc: PWY-6349 TK2119 1a9dc85d23eb9f0be0871985d26d1700 171 Hamap MF_01117 CDP-archaeol synthase [carS]. 14 171 28.167 T 31-10-2018 IPR002726 CDP-archaeol synthase, archaea KEGG: 00564+2.7.7.67|MetaCyc: PWY-6349 TK0876 bdcdcf36ef112793dc4ea7a13ee38ef3 220 Pfam PF03587 EMG1/NEP1 methyltransferase 5 215 8.4E-51 T 31-10-2018 IPR005304 Ribosomal biogenesis, methyltransferase, EMG1/NEP1 GO:0008168 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 TK0876 bdcdcf36ef112793dc4ea7a13ee38ef3 220 Hamap MF_00554 Ribosomal RNA small subunit methyltransferase Nep1 [nep1]. 2 216 40.32 T 31-10-2018 IPR023503 Ribosome biogenesis methyltransferase NEP1, archaea GO:0008168 TK0876 bdcdcf36ef112793dc4ea7a13ee38ef3 220 Gene3D G3DSA:3.40.1280.10 1 219 4.2E-75 T 31-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal TK0876 bdcdcf36ef112793dc4ea7a13ee38ef3 220 SUPERFAMILY SSF75217 1 219 9.81E-63 T 31-10-2018 IPR029028 Alpha/beta knot methyltransferases TK1849 1eab49ae19ef1558481a3c069bb6c223 164 PIRSF PIRSF019115 1 164 2.7E-74 T 31-10-2018 IPR019217 Protein of unknown function DUF2118 TK1849 1eab49ae19ef1558481a3c069bb6c223 164 Gene3D G3DSA:2.40.50.100 97 163 2.2E-30 T 31-10-2018 TK1849 1eab49ae19ef1558481a3c069bb6c223 164 Pfam PF09891 Uncharacterized protein conserved in archaea (DUF2118) 2 163 1.0E-60 T 31-10-2018 IPR019217 Protein of unknown function DUF2118 TK0637 f68cec2c3a0beeb20c6b7cde528e6b54 207 Gene3D G3DSA:3.40.1550.10 1 200 1.3E-43 T 31-10-2018 IPR028976 CheC-like superfamily TK0637 f68cec2c3a0beeb20c6b7cde528e6b54 207 SUPERFAMILY SSF103039 1 198 1.44E-40 T 31-10-2018 IPR028976 CheC-like superfamily TK0637 f68cec2c3a0beeb20c6b7cde528e6b54 207 Pfam PF13690 Chemotaxis phosphatase CheX 66 148 1.1E-6 T 31-10-2018 IPR028051 Chemotaxis phosphatase CheX-like domain TK0637 f68cec2c3a0beeb20c6b7cde528e6b54 207 Pfam PF04509 CheC-like family 10 42 1.5E-4 T 31-10-2018 IPR007597 CheC-like protein GO:0016787 TK1759 f9f61d4170ed94a12f2b4aac993ed9c2 332 SUPERFAMILY SSF161098 102 314 1.9E-6 T 31-10-2018 IPR035906 MetI-like superfamily TK1759 f9f61d4170ed94a12f2b4aac993ed9c2 332 Gene3D G3DSA:1.10.3720.10 96 321 4.7E-9 T 31-10-2018 IPR035906 MetI-like superfamily TK1759 f9f61d4170ed94a12f2b4aac993ed9c2 332 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 123 326 3.8E-43 T 31-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TK0168 c1bb47acf60632cda9a374f19605968b 77 SUPERFAMILY SSF54909 2 72 1.18E-10 T 31-10-2018 IPR011008 Dimeric alpha-beta barrel TK0168 c1bb47acf60632cda9a374f19605968b 77 Pfam PF01037 Lrp/AsnC ligand binding domain 15 72 1.1E-9 T 31-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain TK0168 c1bb47acf60632cda9a374f19605968b 77 Gene3D G3DSA:3.30.70.920 1 71 8.2E-13 T 31-10-2018 TK0117 cbf2f05ed1a5cc9ad0d9e80c8bddc232 386 Gene3D G3DSA:3.30.9.10 88 315 2.8E-141 T 31-10-2018 TK0117 cbf2f05ed1a5cc9ad0d9e80c8bddc232 386 Pfam PF01266 FAD dependent oxidoreductase 12 355 2.4E-73 T 31-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 TK0117 cbf2f05ed1a5cc9ad0d9e80c8bddc232 386 Gene3D G3DSA:3.50.50.60 12 360 2.8E-141 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TK0117 cbf2f05ed1a5cc9ad0d9e80c8bddc232 386 SUPERFAMILY SSF51905 11 376 1.81E-59 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TK0117 cbf2f05ed1a5cc9ad0d9e80c8bddc232 386 SUPERFAMILY SSF54373 224 316 1.31E-9 T 31-10-2018 TK1499 01f55bb2a04602d3bf8a947b8b21b31a 65 ProDom PD006539 RNA POLYMERASE DNA-DIRECTED SUBUNIT TRANSFERASE NUCLEOTIDYLTRANSFERASE METAL-BINDING ZINC TRANSCRIPTION N 10 49 2.0E-16 T 31-10-2018 IPR000268 DNA-directed RNA polymerase, subunit N/Rpb10 GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 TK1499 01f55bb2a04602d3bf8a947b8b21b31a 65 SUPERFAMILY SSF46924 1 63 1.06E-27 T 31-10-2018 IPR023580 RNA polymerase subunit RPB10 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 TK1499 01f55bb2a04602d3bf8a947b8b21b31a 65 Pfam PF01194 RNA polymerases N / 8 kDa subunit 1 58 4.6E-30 T 31-10-2018 IPR000268 DNA-directed RNA polymerase, subunit N/Rpb10 GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 TK1499 01f55bb2a04602d3bf8a947b8b21b31a 65 PIRSF PIRSF005653 1 65 3.9E-31 T 31-10-2018 IPR000268 DNA-directed RNA polymerase, subunit N/Rpb10 GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 TK1499 01f55bb2a04602d3bf8a947b8b21b31a 65 Gene3D G3DSA:1.10.10.60 1 65 2.2E-33 T 31-10-2018 TK1499 01f55bb2a04602d3bf8a947b8b21b31a 65 Hamap MF_00250 DNA-directed RNA polymerase subunit N [rpoN]. 1 63 23.036 T 31-10-2018 IPR000268 DNA-directed RNA polymerase, subunit N/Rpb10 GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 TK1499 01f55bb2a04602d3bf8a947b8b21b31a 65 ProSitePatterns PS01112 RNA polymerases N / 8 Kd subunits signature. 2 11 - T 31-10-2018 IPR020789 RNA polymerases, subunit N, zinc binding site GO:0003677|GO:0003899|GO:0006351|GO:0008270 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 TK0260 89251fdf99ea9de919654d35325f5904 364 Pfam PF00155 Aminotransferase class I and II 21 325 1.1E-39 T 31-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 TK0260 89251fdf99ea9de919654d35325f5904 364 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 197 210 - T 31-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 TK0260 89251fdf99ea9de919654d35325f5904 364 Gene3D G3DSA:3.40.640.10 9 346 1.2E-74 T 31-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TK0260 89251fdf99ea9de919654d35325f5904 364 SUPERFAMILY SSF53383 18 332 2.34E-72 T 31-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TK2269 9ca214376d2f7a5d3e07a0a9b71a03a8 135 SUPERFAMILY SSF143870 2 127 6.67E-26 T 31-10-2018 IPR036504 CGI121/TPRKB superfamily Reactome: R-HSA-6782315 TK2269 9ca214376d2f7a5d3e07a0a9b71a03a8 135 Pfam PF08617 Kinase binding protein CGI-121 41 107 1.8E-4 T 31-10-2018 IPR013926 CGI121/TPRKB Reactome: R-HSA-6782315 TK2269 9ca214376d2f7a5d3e07a0a9b71a03a8 135 Gene3D G3DSA:3.30.2380.10 5 135 2.7E-41 T 31-10-2018 IPR036504 CGI121/TPRKB superfamily Reactome: R-HSA-6782315 TK1295 c2debc4d6ca4805f3d80f5b777ea4128 1103 ProSitePatterns PS00639 Eukaryotic thiol (cysteine) proteases histidine active site. 397 407 - T 31-10-2018 IPR025660 Cysteine peptidase, histidine active site Reactome: R-HSA-2132295 TK1295 c2debc4d6ca4805f3d80f5b777ea4128 1103 Gene3D G3DSA:3.90.70.10 102 304 1.2E-9 T 31-10-2018 TK1295 c2debc4d6ca4805f3d80f5b777ea4128 1103 Gene3D G3DSA:3.90.70.10 305 455 1.5E-15 T 31-10-2018 TK1295 c2debc4d6ca4805f3d80f5b777ea4128 1103 Gene3D G3DSA:2.60.40.10 729 829 1.3E-8 T 31-10-2018 IPR013783 Immunoglobulin-like fold TK1295 c2debc4d6ca4805f3d80f5b777ea4128 1103 Pfam PF00112 Papain family cysteine protease 395 440 1.8E-5 T 31-10-2018 IPR000668 Peptidase C1A, papain C-terminal GO:0006508|GO:0008234 TK1295 c2debc4d6ca4805f3d80f5b777ea4128 1103 SUPERFAMILY SSF54001 74 459 1.55E-33 T 31-10-2018 IPR038765 Papain-like cysteine peptidase superfamily TK1076 7fba8596dd552822531172eb71b26fca 81 SMART SM00966 4 49 1.0E-16 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 TK1076 7fba8596dd552822531172eb71b26fca 81 SUPERFAMILY SSF89447 1 47 4.88E-15 T 31-10-2018 IPR037914 SpoVT-AbrB domain superfamily TK1076 7fba8596dd552822531172eb71b26fca 81 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 4 46 1.1E-12 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 TK1076 7fba8596dd552822531172eb71b26fca 81 Gene3D G3DSA:2.10.260.10 2 42 4.0E-15 T 31-10-2018 TK1076 7fba8596dd552822531172eb71b26fca 81 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 3 45 2.7E-18 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 TK0243 6df44755f209bdb7a6af13152ac34bda 203 Pfam PF01634 ATP phosphoribosyltransferase 44 197 1.2E-45 T 31-10-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 TK0243 6df44755f209bdb7a6af13152ac34bda 203 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 1 175 1.4E-55 T 31-10-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 TK0243 6df44755f209bdb7a6af13152ac34bda 203 Gene3D G3DSA:3.40.190.10 3 190 2.8E-59 T 31-10-2018 TK0243 6df44755f209bdb7a6af13152ac34bda 203 Gene3D G3DSA:3.40.190.10 84 168 2.8E-59 T 31-10-2018 TK0243 6df44755f209bdb7a6af13152ac34bda 203 Hamap MF_01018 ATP phosphoribosyltransferase [hisG]. 1 200 45.778 T 31-10-2018 IPR024893 ATP phosphoribosyltransferase HisG, short form GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17 TK0243 6df44755f209bdb7a6af13152ac34bda 203 ProSitePatterns PS01316 ATP phosphoribosyltransferase signature. 135 156 - T 31-10-2018 IPR018198 ATP phosphoribosyltransferase, conserved site GO:0003879 KEGG: 00340+2.4.2.17 TK0243 6df44755f209bdb7a6af13152ac34bda 203 SUPERFAMILY SSF53850 1 199 5.79E-58 T 31-10-2018 TK1900 4be3f8ac7438e2a71f0f319c27cc4b19 343 Pfam PF07885 Ion channel 34 106 2.4E-18 T 31-10-2018 IPR013099 Potassium channel domain TK1900 4be3f8ac7438e2a71f0f319c27cc4b19 343 Pfam PF02254 TrkA-N domain 125 246 8.4E-18 T 31-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 TK1900 4be3f8ac7438e2a71f0f319c27cc4b19 343 PRINTS PR01333 Two pore domain K+ channel signature 126 135 2.1E-7 T 31-10-2018 IPR003280 Two pore domain potassium channel GO:0005267|GO:0016020|GO:0071805 Reactome: R-HSA-5576886 TK1900 4be3f8ac7438e2a71f0f319c27cc4b19 343 PRINTS PR01333 Two pore domain K+ channel signature 62 90 2.1E-7 T 31-10-2018 IPR003280 Two pore domain potassium channel GO:0005267|GO:0016020|GO:0071805 Reactome: R-HSA-5576886 TK1900 4be3f8ac7438e2a71f0f319c27cc4b19 343 Gene3D G3DSA:1.10.287.70 4 119 9.6E-22 T 31-10-2018 TK1900 4be3f8ac7438e2a71f0f319c27cc4b19 343 SUPERFAMILY SSF81324 19 134 6.67E-27 T 31-10-2018 TK1900 4be3f8ac7438e2a71f0f319c27cc4b19 343 SUPERFAMILY SSF51735 121 269 2.21E-21 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily TK1900 4be3f8ac7438e2a71f0f319c27cc4b19 343 Gene3D G3DSA:3.40.50.720 122 271 8.5E-26 T 31-10-2018 TK0662 ca115aaec4b90352b9dd511fd90641b9 710 TIGRFAM TIGR04288 CGP_CTERM: CGP-CTERM domain 691 709 1.0E-6 T 31-10-2018 IPR027552 CGP-CTERM domain TK0662 ca115aaec4b90352b9dd511fd90641b9 710 Pfam PF16286 Domain of unknown function (DUF4932) 35 217 8.3E-10 T 31-10-2018 IPR032560 Protein of unknown function DUF4932 TK0915 dde03e45c92e1dd257879f4e76b4a2ca 248 SUPERFAMILY SSF52540 1 244 1.19E-47 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK0915 dde03e45c92e1dd257879f4e76b4a2ca 248 Gene3D G3DSA:3.40.50.300 2 242 6.9E-48 T 31-10-2018 TK0915 dde03e45c92e1dd257879f4e76b4a2ca 248 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 3 221 8.5E-19 T 31-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain TK1534 cd4f46d1e89167e90a3060961bc29bc6 98 SUPERFAMILY SSF55159 5 91 2.09E-23 T 31-10-2018 IPR036877 SUI1 domain superfamily GO:0003743|GO:0006413 TK1534 cd4f46d1e89167e90a3060961bc29bc6 98 PIRSF PIRSF037511 5 97 4.6E-26 T 31-10-2018 IPR005872 Archaeal/bacterial translation initiation factor SUI1 GO:0003743 TK1534 cd4f46d1e89167e90a3060961bc29bc6 98 Hamap MF_00604 Protein translation factor SUI1 homolog. 2 93 26.962 T 31-10-2018 IPR022851 Translation factor SUI1 homolog, archaea TK1534 cd4f46d1e89167e90a3060961bc29bc6 98 Gene3D G3DSA:3.30.780.10 20 98 3.6E-29 T 31-10-2018 TK1534 cd4f46d1e89167e90a3060961bc29bc6 98 Pfam PF01253 Translation initiation factor SUI1 20 90 2.8E-20 T 31-10-2018 IPR001950 SUI1 domain GO:0003743|GO:0006413 TK1534 cd4f46d1e89167e90a3060961bc29bc6 98 TIGRFAM TIGR01158 SUI1_rel: putative translation initiation factor SUI1 4 96 3.0E-36 T 31-10-2018 IPR005872 Archaeal/bacterial translation initiation factor SUI1 GO:0003743 TK1781 1c382bd8eabd01d63cab56c5a8965de4 422 SUPERFAMILY SSF55031 212 323 8.82E-19 T 31-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain TK1781 1c382bd8eabd01d63cab56c5a8965de4 422 Pfam PF07687 Peptidase dimerisation domain 207 318 1.7E-20 T 31-10-2018 IPR011650 Peptidase M20, dimerisation domain TK1781 1c382bd8eabd01d63cab56c5a8965de4 422 Gene3D G3DSA:3.40.630.10 324 422 2.1E-12 T 31-10-2018 TK1781 1c382bd8eabd01d63cab56c5a8965de4 422 TIGRFAM TIGR01910 DapE-ArgE: peptidase, ArgE/DapE family 21 415 6.1E-83 T 31-10-2018 IPR010182 N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine deformylase/Succinyl-diaminopimelate desuccinylase TK1781 1c382bd8eabd01d63cab56c5a8965de4 422 Pfam PF01546 Peptidase family M20/M25/M40 97 420 7.9E-39 T 31-10-2018 IPR002933 Peptidase M20 GO:0016787 TK1781 1c382bd8eabd01d63cab56c5a8965de4 422 Gene3D G3DSA:3.30.70.360 214 323 2.6E-19 T 31-10-2018 TK1781 1c382bd8eabd01d63cab56c5a8965de4 422 SUPERFAMILY SSF53187 7 420 3.02E-63 T 31-10-2018 TK1781 1c382bd8eabd01d63cab56c5a8965de4 422 Gene3D G3DSA:3.40.630.10 10 213 7.2E-44 T 31-10-2018 TK1926 29f7cb030a0278225a7459329e925fa4 113 SUPERFAMILY SSF117782 7 112 2.09E-35 T 31-10-2018 IPR035439 UPF0145 domain superfamily TK1926 29f7cb030a0278225a7459329e925fa4 113 Gene3D G3DSA:3.30.110.70 7 113 1.2E-30 T 31-10-2018 TK1926 29f7cb030a0278225a7459329e925fa4 113 Pfam PF01906 Putative heavy-metal-binding 7 109 9.3E-36 T 31-10-2018 IPR002765 Uncharacterised protein family UPF0145 TK1926 29f7cb030a0278225a7459329e925fa4 113 Hamap MF_00338 UPF0145 protein YbjQ [ybjQ]. 7 109 24.772 T 31-10-2018 IPR002765 Uncharacterised protein family UPF0145 TK1843 65b73bf1c1aa7f820075d2246f12ebd6 278 Gene3D G3DSA:3.40.1190.20 1 276 3.7E-63 T 31-10-2018 IPR029056 Ribokinase-like TK1843 65b73bf1c1aa7f820075d2246f12ebd6 278 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 231 244 - T 31-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 TK1843 65b73bf1c1aa7f820075d2246f12ebd6 278 Pfam PF00294 pfkB family carbohydrate kinase 2 270 1.1E-40 T 31-10-2018 IPR011611 Carbohydrate kinase PfkB TK1843 65b73bf1c1aa7f820075d2246f12ebd6 278 PRINTS PR00990 Ribokinase signature 161 176 1.3E-7 T 31-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 TK1843 65b73bf1c1aa7f820075d2246f12ebd6 278 PRINTS PR00990 Ribokinase signature 22 41 1.3E-7 T 31-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 TK1843 65b73bf1c1aa7f820075d2246f12ebd6 278 PRINTS PR00990 Ribokinase signature 200 211 1.3E-7 T 31-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 TK1843 65b73bf1c1aa7f820075d2246f12ebd6 278 SUPERFAMILY SSF53613 1 275 6.08E-59 T 31-10-2018 IPR029056 Ribokinase-like TK0361 434df60817b4a9440ee19d1168dcfedc 142 ProDom PD012969 UPF0211 RIKEN CDNA ENRICHED MALE FULL-LENGTH LIBRARY ZBTB8OS ADULT C43H8.1 8 142 7.0E-51 T 31-10-2018 IPR023572 Archease domain Reactome: R-HSA-6784531 TK0361 434df60817b4a9440ee19d1168dcfedc 142 Pfam PF01951 Archease protein family (MTH1598/TM1083) 4 141 1.6E-46 T 31-10-2018 IPR023572 Archease domain Reactome: R-HSA-6784531 TK0361 434df60817b4a9440ee19d1168dcfedc 142 SUPERFAMILY SSF69819 2 142 7.32E-49 T 31-10-2018 IPR036820 Archease domain superfamily Reactome: R-HSA-6784531 TK0361 434df60817b4a9440ee19d1168dcfedc 142 Gene3D G3DSA:3.55.10.10 1 142 2.4E-53 T 31-10-2018 IPR036820 Archease domain superfamily Reactome: R-HSA-6784531 TK0361 434df60817b4a9440ee19d1168dcfedc 142 Hamap MF_01222 Protein archease. 2 142 42.149 T 31-10-2018 IPR022952 Archease, archaea TK1119 79611ff044087d280b1b37c81beea409 115 PIRSF PIRSF006113 1 115 4.5E-36 T 31-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 TK1119 79611ff044087d280b1b37c81beea409 115 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 5 113 4.5E-30 T 31-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 TK1119 79611ff044087d280b1b37c81beea409 115 Gene3D G3DSA:3.30.479.10 1 115 2.6E-41 T 31-10-2018 IPR038418 6-pyruvoyl tetrahydropterin synthase/QueD superfamily Reactome: R-HSA-1474151 TK1119 79611ff044087d280b1b37c81beea409 115 SUPERFAMILY SSF55620 1 114 2.5E-33 T 31-10-2018 TK1652 93a42bd0c06ef5ab103bfe2bf4b5dfc0 140 Gene3D G3DSA:3.10.129.10 1 139 1.6E-37 T 31-10-2018 TK1652 93a42bd0c06ef5ab103bfe2bf4b5dfc0 140 SUPERFAMILY SSF54637 19 129 1.12E-23 T 31-10-2018 IPR029069 HotDog domain superfamily TK1652 93a42bd0c06ef5ab103bfe2bf4b5dfc0 140 Pfam PF03061 Thioesterase superfamily 40 92 3.0E-7 T 31-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 TK1826 9427281f146c25ebce689f0e25da1b90 100 Pfam PF13601 Winged helix DNA-binding domain 17 94 1.6E-19 T 31-10-2018 IPR027395 Winged helix DNA-binding domain TK1826 9427281f146c25ebce689f0e25da1b90 100 Gene3D G3DSA:1.10.10.10 1 99 2.3E-26 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TK1826 9427281f146c25ebce689f0e25da1b90 100 SUPERFAMILY SSF46785 8 98 2.08E-18 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TK0999 51fb7c7a969cb4447697c51952076946 260 Gene3D G3DSA:3.40.50.1820 1 259 4.8E-68 T 31-10-2018 IPR029058 Alpha/Beta hydrolase fold TK0999 51fb7c7a969cb4447697c51952076946 260 PRINTS PR00111 Alpha/beta hydrolase fold signature 83 96 5.7E-6 T 31-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TK0999 51fb7c7a969cb4447697c51952076946 260 PRINTS PR00111 Alpha/beta hydrolase fold signature 195 209 5.7E-6 T 31-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TK0999 51fb7c7a969cb4447697c51952076946 260 PRINTS PR00111 Alpha/beta hydrolase fold signature 40 55 5.7E-6 T 31-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TK0999 51fb7c7a969cb4447697c51952076946 260 PRINTS PR00111 Alpha/beta hydrolase fold signature 97 110 5.7E-6 T 31-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TK0999 51fb7c7a969cb4447697c51952076946 260 SUPERFAMILY SSF53474 5 253 2.26E-49 T 31-10-2018 IPR029058 Alpha/Beta hydrolase fold TK0999 51fb7c7a969cb4447697c51952076946 260 Pfam PF12146 Serine aminopeptidase, S33 11 240 9.2E-69 T 31-10-2018 IPR022742 Serine aminopeptidase, S33 TK1211 37cf93577fe5eb66910600f9b52e8bab 443 Gene3D G3DSA:3.90.1150.10 5 420 1.4E-146 T 31-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TK1211 37cf93577fe5eb66910600f9b52e8bab 443 PIRSF PIRSF000521 122 427 1.7E-32 T 31-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TK1211 37cf93577fe5eb66910600f9b52e8bab 443 PIRSF PIRSF000521 2 130 8.5E-7 T 31-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TK1211 37cf93577fe5eb66910600f9b52e8bab 443 Pfam PF00202 Aminotransferase class-III 21 424 1.1E-110 T 31-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TK1211 37cf93577fe5eb66910600f9b52e8bab 443 SUPERFAMILY SSF53383 16 427 1.01E-127 T 31-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TK1211 37cf93577fe5eb66910600f9b52e8bab 443 Gene3D G3DSA:3.40.640.10 59 324 1.4E-146 T 31-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TK1556 e5c7f7b19d008509c3eb9c5fe23d6644 304 Pfam PF01171 PP-loop family 49 221 2.3E-13 T 31-10-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 TK1556 e5c7f7b19d008509c3eb9c5fe23d6644 304 Gene3D G3DSA:3.40.50.620 1 303 4.5E-92 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TK1556 e5c7f7b19d008509c3eb9c5fe23d6644 304 SUPERFAMILY SSF52402 24 245 5.95E-51 T 31-10-2018 TK1556 e5c7f7b19d008509c3eb9c5fe23d6644 304 TIGRFAM TIGR00269 TIGR00269: TIGR00269 family protein 192 291 1.6E-26 T 31-10-2018 IPR000541 Cytoplasmic tRNA 2-thiolation protein 1 GO:0000049|GO:0002098|GO:0034227 Reactome: R-HSA-6782315 TK1556 e5c7f7b19d008509c3eb9c5fe23d6644 304 PIRSF PIRSF004976 1 302 1.7E-96 T 31-10-2018 IPR035107 tRNA thiolation protein, TtcA/Ctu1 type GO:0008033 Reactome: R-HSA-6782315 TK1695 f18153bb0613f041d7406224d15c1179 57 Pfam PF01599 Ribosomal protein S27a 12 53 1.6E-22 T 31-10-2018 IPR002906 Ribosomal protein S27a GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 TK1695 f18153bb0613f041d7406224d15c1179 57 Hamap MF_00777 30S ribosomal protein S27ae [rps27ae]. 11 56 19.566 T 31-10-2018 IPR022845 Ribosomal protein S27ae TK1695 f18153bb0613f041d7406224d15c1179 57 SUPERFAMILY SSF57829 11 57 1.83E-21 T 31-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 TK1695 f18153bb0613f041d7406224d15c1179 57 SMART SM01402 11 53 7.5E-25 T 31-10-2018 IPR002906 Ribosomal protein S27a GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 TK1695 f18153bb0613f041d7406224d15c1179 57 Gene3D G3DSA:2.20.25.660 1 56 1.3E-20 T 31-10-2018 IPR038582 S27a-like superfamily Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 TK2065 8b6e5d716dcfc74289b09ed82120d775 72 Gene3D G3DSA:2.40.50.140 6 71 2.0E-26 T 31-10-2018 TK2065 8b6e5d716dcfc74289b09ed82120d775 72 Pfam PF01938 TRAM domain 15 71 9.8E-15 T 31-10-2018 IPR002792 TRAM domain TK2065 8b6e5d716dcfc74289b09ed82120d775 72 SUPERFAMILY SSF50249 11 72 1.89E-17 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold TK1445 50a2a5ac19d297c029365558ef280ecf 366 Pfam PF00696 Amino acid kinase family 7 264 1.9E-38 T 31-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 TK1445 50a2a5ac19d297c029365558ef280ecf 366 Gene3D G3DSA:3.40.1160.10 7 277 1.8E-59 T 31-10-2018 IPR036393 Acetylglutamate kinase-like superfamily TK1445 50a2a5ac19d297c029365558ef280ecf 366 ProSitePatterns PS00324 Aspartokinase signature. 9 17 - T 31-10-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 TK1445 50a2a5ac19d297c029365558ef280ecf 366 SUPERFAMILY SSF53633 7 276 1.96E-53 T 31-10-2018 IPR036393 Acetylglutamate kinase-like superfamily TK1445 50a2a5ac19d297c029365558ef280ecf 366 TIGRFAM TIGR02078 AspKin_pair: putative Pyrococcus aspartate kinase subunit 8 294 2.8E-96 T 31-10-2018 IPR011819 Pyrococcus aspartate kinase subunit, putative TK0052 752769e75009839c23eaaa04a1197728 209 SUPERFAMILY SSF56784 1 186 3.2E-42 T 31-10-2018 IPR036412 HAD-like superfamily TK0052 752769e75009839c23eaaa04a1197728 209 Pfam PF12710 haloacid dehalogenase-like hydrolase 5 171 5.3E-22 T 31-10-2018 TK0052 752769e75009839c23eaaa04a1197728 209 Gene3D G3DSA:3.40.50.1000 3 187 8.4E-53 T 31-10-2018 IPR023214 HAD superfamily TK0052 752769e75009839c23eaaa04a1197728 209 Gene3D G3DSA:1.10.150.210 14 75 8.4E-53 T 31-10-2018 IPR023190 Phosphoserine phosphatase, domain 2 GO:0004647|GO:0006564 KEGG: 00260+3.1.3.3|KEGG: 00680+3.1.3.3|Reactome: R-HSA-977347 TK0052 752769e75009839c23eaaa04a1197728 209 TIGRFAM TIGR01491 HAD-SF-IB-PSPlk: phosphoserine phosphatase-like hydrolase, archaeal 1 183 1.7E-55 T 31-10-2018 IPR006386 HAD-superfamily hydrolase, subfamily IB, PSPase-like, archaeal TK0052 752769e75009839c23eaaa04a1197728 209 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 4 172 1.2E-32 T 31-10-2018 TK0853 84b22bd6518dc4dafed3eb8a73dbb0d9 335 Pfam PF02277 Phosphoribosyltransferase 100 250 1.6E-5 T 31-10-2018 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 TK0853 84b22bd6518dc4dafed3eb8a73dbb0d9 335 Hamap MF_01086 UPF0284 protein . 1 335 139.237 T 31-10-2018 IPR002805 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, putative TK0853 84b22bd6518dc4dafed3eb8a73dbb0d9 335 TIGRFAM TIGR00303 TIGR00303: TIGR00303 family protein 2 323 8.3E-102 T 31-10-2018 IPR002805 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, putative TK0853 84b22bd6518dc4dafed3eb8a73dbb0d9 335 SUPERFAMILY SSF52733 18 327 2.22E-42 T 31-10-2018 IPR036087 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like superfamily GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 TK0853 84b22bd6518dc4dafed3eb8a73dbb0d9 335 Gene3D G3DSA:3.40.50.10210 1 333 6.7E-128 T 31-10-2018 TK0787 c7523e9de155a2211f5e5cb9f1e1660a 256 SUPERFAMILY SSF56655 6 248 3.4E-57 T 31-10-2018 TK0787 c7523e9de155a2211f5e5cb9f1e1660a 256 Gene3D G3DSA:3.30.540.10 2 139 4.3E-36 T 31-10-2018 TK0787 c7523e9de155a2211f5e5cb9f1e1660a 256 Gene3D G3DSA:3.40.190.80 146 253 3.2E-31 T 31-10-2018 TK0787 c7523e9de155a2211f5e5cb9f1e1660a 256 PRINTS PR00377 Inositol monophosphatase superfamily signature 80 96 2.1E-31 T 31-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 TK0787 c7523e9de155a2211f5e5cb9f1e1660a 256 PRINTS PR00377 Inositol monophosphatase superfamily signature 40 60 2.1E-31 T 31-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 TK0787 c7523e9de155a2211f5e5cb9f1e1660a 256 PRINTS PR00377 Inositol monophosphatase superfamily signature 129 152 2.1E-31 T 31-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 TK0787 c7523e9de155a2211f5e5cb9f1e1660a 256 PRINTS PR00377 Inositol monophosphatase superfamily signature 197 221 2.1E-31 T 31-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 TK0787 c7523e9de155a2211f5e5cb9f1e1660a 256 PRINTS PR00377 Inositol monophosphatase superfamily signature 164 185 2.1E-31 T 31-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 TK0787 c7523e9de155a2211f5e5cb9f1e1660a 256 Pfam PF00459 Inositol monophosphatase family 7 253 2.3E-39 T 31-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 TK0787 c7523e9de155a2211f5e5cb9f1e1660a 256 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 80 92 - T 31-10-2018 IPR020583 Inositol monophosphatase, metal-binding site TK1214 73ea90ce903b9da0a0400f5c8ecc12b6 217 Pfam PF12838 4Fe-4S dicluster domain 60 114 3.8E-11 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TK1214 73ea90ce903b9da0a0400f5c8ecc12b6 217 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 61 72 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TK1214 73ea90ce903b9da0a0400f5c8ecc12b6 217 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 100 111 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TK1214 73ea90ce903b9da0a0400f5c8ecc12b6 217 Gene3D G3DSA:3.30.70.3270 39 176 2.1E-23 T 31-10-2018 TK1214 73ea90ce903b9da0a0400f5c8ecc12b6 217 SUPERFAMILY SSF54862 22 121 4.6E-23 T 31-10-2018 TK0073 c9d8a79b2309b554b7554d518fb07a08 297 Pfam PF16795 Archaeal phage integrase 124 286 1.3E-61 T 31-10-2018 IPR031857 Integrase SSV1, C-terminal TK0073 c9d8a79b2309b554b7554d518fb07a08 297 Gene3D G3DSA:1.10.443.10 124 290 2.2E-44 T 31-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 TK0073 c9d8a79b2309b554b7554d518fb07a08 297 SUPERFAMILY SSF56349 38 275 8.24E-12 T 31-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 TK0061 0f44ab50fb91621b8cd16212d41a168a 532 SMART SM00460 333 391 0.0058 T 31-10-2018 IPR002931 Transglutaminase-like TK0061 0f44ab50fb91621b8cd16212d41a168a 532 SUPERFAMILY SSF54001 289 455 2.13E-10 T 31-10-2018 IPR038765 Papain-like cysteine peptidase superfamily TK0061 0f44ab50fb91621b8cd16212d41a168a 532 Gene3D G3DSA:3.10.620.30 278 404 1.1E-6 T 31-10-2018 TK0061 0f44ab50fb91621b8cd16212d41a168a 532 Pfam PF01841 Transglutaminase-like superfamily 293 388 4.2E-7 T 31-10-2018 IPR002931 Transglutaminase-like TK2271 0e79b98cc363c432a70131e93fc73013 413 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 30 355 2.1E-111 T 31-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 TK2271 0e79b98cc363c432a70131e93fc73013 413 SUPERFAMILY SSF52490 36 239 9.29E-56 T 31-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 TK2271 0e79b98cc363c432a70131e93fc73013 413 ProSitePatterns PS01135 FtsZ protein signature 2. 121 142 - T 31-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 TK2271 0e79b98cc363c432a70131e93fc73013 413 Gene3D G3DSA:3.30.1330.20 256 359 1.2E-28 T 31-10-2018 IPR037103 Tubulin/FtsZ, C-terminal domain superfamily Reactome: R-HSA-380320 TK2271 0e79b98cc363c432a70131e93fc73013 413 SMART SM00865 238 355 1.2E-39 T 31-10-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-380320 TK2271 0e79b98cc363c432a70131e93fc73013 413 Gene3D G3DSA:3.40.50.1440 27 251 1.0E-68 T 31-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 TK2271 0e79b98cc363c432a70131e93fc73013 413 SMART SM00864 37 236 7.8E-83 T 31-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TK2271 0e79b98cc363c432a70131e93fc73013 413 ProSitePatterns PS01134 FtsZ protein signature 1. 68 102 - T 31-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 TK2271 0e79b98cc363c432a70131e93fc73013 413 PRINTS PR00423 Cell division protein FtsZ signature 122 142 2.2E-35 T 31-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TK2271 0e79b98cc363c432a70131e93fc73013 413 PRINTS PR00423 Cell division protein FtsZ signature 243 264 2.2E-35 T 31-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TK2271 0e79b98cc363c432a70131e93fc73013 413 PRINTS PR00423 Cell division protein FtsZ signature 158 179 2.2E-35 T 31-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TK2271 0e79b98cc363c432a70131e93fc73013 413 PRINTS PR00423 Cell division protein FtsZ signature 220 242 2.2E-35 T 31-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TK2271 0e79b98cc363c432a70131e93fc73013 413 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 33 395 33.642 T 31-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 TK2271 0e79b98cc363c432a70131e93fc73013 413 SUPERFAMILY SSF55307 238 352 6.87E-36 T 31-10-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 TK2271 0e79b98cc363c432a70131e93fc73013 413 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 37 205 2.5E-43 T 31-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TK2271 0e79b98cc363c432a70131e93fc73013 413 Pfam PF12327 FtsZ family, C-terminal domain 253 347 9.5E-26 T 31-10-2018 IPR024757 Cell division protein FtsZ, C-terminal TK1600 32a493463920fdd7ac4a70abe14b5aeb 365 Gene3D G3DSA:1.20.1690.10 111 208 9.3E-64 T 31-10-2018 IPR035067 V-type ATPase subunit c Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TK1600 32a493463920fdd7ac4a70abe14b5aeb 365 Hamap MF_00314 V-type ATP synthase subunit C [atpC]. 30 362 24.928 T 31-10-2018 IPR014272 ATPase, V0 complex, c subunit GO:0033179|GO:0046961 TK1600 32a493463920fdd7ac4a70abe14b5aeb 365 Gene3D G3DSA:1.20.1690.10 219 322 9.3E-64 T 31-10-2018 IPR035067 V-type ATPase subunit c Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TK1600 32a493463920fdd7ac4a70abe14b5aeb 365 TIGRFAM TIGR02923 AhaC: ATP synthase A1, C subunit 31 361 1.6E-130 T 31-10-2018 IPR014272 ATPase, V0 complex, c subunit GO:0033179|GO:0046961 TK1600 32a493463920fdd7ac4a70abe14b5aeb 365 Gene3D G3DSA:1.10.132.50 34 353 9.3E-64 T 31-10-2018 TK1600 32a493463920fdd7ac4a70abe14b5aeb 365 Pfam PF01992 ATP synthase (C/AC39) subunit 38 359 7.8E-70 T 31-10-2018 IPR002843 ATPase, V0 complex, c/d subunit Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TK1600 32a493463920fdd7ac4a70abe14b5aeb 365 SUPERFAMILY SSF103486 34 362 1.29E-83 T 31-10-2018 IPR036079 V-type ATP synthase subunit C-like Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TK1549 a75b55bfe5970bac871227d4a38da105 193 PIRSF PIRSF018868 1 193 4.5E-110 T 31-10-2018 IPR016737 Uncharacterised conserved protein UCP018868 TK1549 a75b55bfe5970bac871227d4a38da105 193 Pfam PF00437 Type II/IV secretion system protein 7 124 6.5E-11 T 31-10-2018 IPR001482 Type II/IV secretion system protein TK1549 a75b55bfe5970bac871227d4a38da105 193 SUPERFAMILY SSF52540 18 169 8.38E-13 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK1549 a75b55bfe5970bac871227d4a38da105 193 Gene3D G3DSA:3.40.50.300 5 190 3.6E-17 T 31-10-2018 TK1382 253eb336efb44ad89a75671c499506d5 204 SMART SM00664 84 180 5.1E-17 T 31-10-2018 IPR005018 DOMON domain TK1382 253eb336efb44ad89a75671c499506d5 204 SUPERFAMILY SSF49344 78 194 1.61E-8 T 31-10-2018 TK1382 253eb336efb44ad89a75671c499506d5 204 Pfam PF03351 DOMON domain 60 180 5.3E-28 T 31-10-2018 IPR005018 DOMON domain TK0680 97f7af65461887b46140d24a22b9cdf2 277 Gene3D G3DSA:1.20.1540.10 6 198 5.8E-6 T 31-10-2018 IPR035952 Rhomboid-like superfamily TK0680 97f7af65461887b46140d24a22b9cdf2 277 Pfam PF01694 Rhomboid family 47 198 4.7E-5 T 31-10-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 TK0680 97f7af65461887b46140d24a22b9cdf2 277 SUPERFAMILY SSF144091 20 184 1.57E-6 T 31-10-2018 TK1960 231b4cdf4a137c62db6ddaa4e7aae26a 125 SUPERFAMILY SSF50249 23 89 4.74E-6 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold TK2123 82b7c8024d3c43e8de168ab179d0af04 341 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 12 321 5.6E-58 T 31-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD TK2123 82b7c8024d3c43e8de168ab179d0af04 341 TIGRFAM TIGR00374 TIGR00374: TIGR00374 family protein 15 337 1.5E-62 T 31-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD TK1816 986499bf2b360f04fb1c51e10d2db81b 61 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 16 59 9.6E-8 T 31-10-2018 IPR003477 mRNA interferase PemK-like GO:0003677 TK1816 986499bf2b360f04fb1c51e10d2db81b 61 Gene3D G3DSA:2.30.30.110 29 61 4.1E-6 T 31-10-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor TK1816 986499bf2b360f04fb1c51e10d2db81b 61 SUPERFAMILY SSF50118 15 60 6.76E-9 T 31-10-2018 TK1501 f22d59825afdab5c94f43cd4196d068f 142 PIRSF PIRSF002181 1 142 3.1E-43 T 31-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 TK1501 f22d59825afdab5c94f43cd4196d068f 142 SUPERFAMILY SSF52161 2 142 7.46E-45 T 31-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 TK1501 f22d59825afdab5c94f43cd4196d068f 142 Gene3D G3DSA:3.90.1180.10 1 142 9.3E-58 T 31-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 TK1501 f22d59825afdab5c94f43cd4196d068f 142 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 1 132 20.556 T 31-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 TK1501 f22d59825afdab5c94f43cd4196d068f 142 TIGRFAM TIGR01077 L13_A_E: ribosomal protein uL13 3 142 2.6E-65 T 31-10-2018 IPR005755 Ribosomal protein L13, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 TK1501 f22d59825afdab5c94f43cd4196d068f 142 Pfam PF00572 Ribosomal protein L13 3 103 2.0E-11 T 31-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 TK1501 f22d59825afdab5c94f43cd4196d068f 142 ProSitePatterns PS00783 Ribosomal protein L13 signature. 79 102 - T 31-10-2018 IPR023563 Ribosomal protein L13, conserved site GO:0003735|GO:0005840|GO:0006412 TK0961 8a37e29de7478ee2415070b7b6aa7ed4 331 Pfam PF00586 AIR synthase related protein, N-terminal domain 48 142 3.3E-14 T 31-10-2018 IPR016188 PurM-like, N-terminal domain TK0961 8a37e29de7478ee2415070b7b6aa7ed4 331 PIRSF PIRSF005644 2 328 1.6E-62 T 31-10-2018 IPR011854 Carbamoyl dehydratase HypE TK0961 8a37e29de7478ee2415070b7b6aa7ed4 331 SUPERFAMILY SSF56042 151 312 2.24E-24 T 31-10-2018 IPR036676 PurM-like, C-terminal domain superfamily TK0961 8a37e29de7478ee2415070b7b6aa7ed4 331 Pfam PF02769 AIR synthase related protein, C-terminal domain 153 305 3.2E-14 T 31-10-2018 IPR010918 PurM-like, C-terminal domain TK0961 8a37e29de7478ee2415070b7b6aa7ed4 331 SUPERFAMILY SSF55326 5 146 4.19E-23 T 31-10-2018 IPR036921 PurM-like, N-terminal domain superfamily TK0961 8a37e29de7478ee2415070b7b6aa7ed4 331 Gene3D G3DSA:3.90.650.10 151 327 2.6E-29 T 31-10-2018 IPR036676 PurM-like, C-terminal domain superfamily TK0961 8a37e29de7478ee2415070b7b6aa7ed4 331 Gene3D G3DSA:3.30.1330.10 3 145 5.2E-26 T 31-10-2018 IPR036921 PurM-like, N-terminal domain superfamily TK0723 7a32bf1ba176000001d0304218c4566c 139 Gene3D G3DSA:3.30.420.130 2 130 1.0E-14 T 31-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily TK0723 7a32bf1ba176000001d0304218c4566c 139 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 16 117 1.0E-15 T 31-10-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis TK0723 7a32bf1ba176000001d0304218c4566c 139 SUPERFAMILY SSF53146 5 118 1.83E-14 T 31-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily TK0715 126e80c988cc1cfa9af9556a811697c8 75 SMART SM00899 2 73 3.1E-19 T 31-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 TK0715 126e80c988cc1cfa9af9556a811697c8 75 Gene3D G3DSA:2.30.30.90 2 75 1.2E-20 T 31-10-2018 IPR038157 Ferrous iron transporter, core domain TK0715 126e80c988cc1cfa9af9556a811697c8 75 Pfam PF04023 FeoA domain 2 72 7.0E-21 T 31-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 TK0715 126e80c988cc1cfa9af9556a811697c8 75 SUPERFAMILY SSF50037 4 74 1.14E-16 T 31-10-2018 IPR008988 Transcriptional repressor, C-terminal TK0588 2b9f9bf6eeb3c004df4ee9fedefa0b50 140 PIRSF PIRSF019240 4 138 2.2E-28 T 31-10-2018 IPR016752 Uncharacterised conserved protein UCP019240, SpoVT/AbrB-related TK0588 2b9f9bf6eeb3c004df4ee9fedefa0b50 140 SUPERFAMILY SSF89447 20 51 4.19E-5 T 31-10-2018 IPR037914 SpoVT-AbrB domain superfamily TK0588 2b9f9bf6eeb3c004df4ee9fedefa0b50 140 SUPERFAMILY SSF89447 64 99 6.63E-7 T 31-10-2018 IPR037914 SpoVT-AbrB domain superfamily TK0588 2b9f9bf6eeb3c004df4ee9fedefa0b50 140 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 68 103 1.9E-7 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 TK0588 2b9f9bf6eeb3c004df4ee9fedefa0b50 140 Gene3D G3DSA:2.10.260.10 12 105 1.4E-24 T 31-10-2018 TK0505 92516cf67046dbb8958ae736a101ace5 325 Gene3D G3DSA:1.20.58.340 248 325 5.2E-35 T 31-10-2018 TK0505 92516cf67046dbb8958ae736a101ace5 325 Gene3D G3DSA:3.30.460.20 1 134 1.3E-23 T 31-10-2018 TK0505 92516cf67046dbb8958ae736a101ace5 325 Pfam PF01544 CorA-like Mg2+ transporter protein 38 321 6.6E-68 T 31-10-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 TK0505 92516cf67046dbb8958ae736a101ace5 325 TIGRFAM TIGR00383 corA: magnesium and cobalt transport protein CorA 9 325 1.7E-88 T 31-10-2018 IPR004488 Magnesium/cobalt transport protein CorA GO:0006824|GO:0015087|GO:0015095|GO:0015693|GO:0016020 TK0505 92516cf67046dbb8958ae736a101ace5 325 Gene3D G3DSA:1.20.58.340 135 246 2.6E-31 T 31-10-2018 TK0505 92516cf67046dbb8958ae736a101ace5 325 SUPERFAMILY SSF143865 6 258 1.57E-58 T 31-10-2018 TK0505 92516cf67046dbb8958ae736a101ace5 325 SUPERFAMILY SSF144083 260 323 8.63E-23 T 31-10-2018 TK1137 5c33e300d89b628c0a56da6ae8383f4d 259 Pfam PF01975 Survival protein SurE 3 192 1.5E-52 T 31-10-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 TK1137 5c33e300d89b628c0a56da6ae8383f4d 259 Gene3D G3DSA:3.40.1210.10 1 258 2.6E-82 T 31-10-2018 IPR036523 SurE-like phosphatase/nucleotidase superfamily GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 TK1137 5c33e300d89b628c0a56da6ae8383f4d 259 Hamap MF_00060 5'/3'-nucleotidase SurE [surE]. 1 259 32.155 T 31-10-2018 IPR030048 Survival protein SurE GO:0008252 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 TK1137 5c33e300d89b628c0a56da6ae8383f4d 259 TIGRFAM TIGR00087 surE: 5'/3'-nucleotidase SurE 1 243 1.5E-68 T 31-10-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 TK1137 5c33e300d89b628c0a56da6ae8383f4d 259 SUPERFAMILY SSF64167 1 255 6.41E-72 T 31-10-2018 TK1127 bd2acf306c94a0a3163f3d36f08ea090 131 Gene3D G3DSA:1.20.120.330 2 126 2.0E-33 T 31-10-2018 TK1127 bd2acf306c94a0a3163f3d36f08ea090 131 Pfam PF05168 HEPN domain 7 121 2.1E-28 T 31-10-2018 IPR007842 HEPN domain TK0142 bcb3bfbeb8775dd968f80b05b726abe5 334 SUPERFAMILY SSF46785 266 330 1.08E-11 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TK0142 bcb3bfbeb8775dd968f80b05b726abe5 334 Pfam PF04122 Putative cell wall binding repeat 2 112 190 1.4E-8 T 31-10-2018 IPR007253 Putative cell wall binding repeat 2 TK0142 bcb3bfbeb8775dd968f80b05b726abe5 334 Gene3D G3DSA:1.10.10.10 265 330 2.0E-10 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TK0142 bcb3bfbeb8775dd968f80b05b726abe5 334 Pfam PF13412 Winged helix-turn-helix DNA-binding 267 314 1.9E-6 T 31-10-2018 TK0630 aec79729cb3f18dd71d74d59ae70d4e0 438 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 214 387 5.8E-43 T 31-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TK0630 aec79729cb3f18dd71d74d59ae70d4e0 438 SUPERFAMILY SSF58104 125 430 8.63E-64 T 31-10-2018 TK0630 aec79729cb3f18dd71d74d59ae70d4e0 438 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 183 212 3.5E-24 T 31-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TK0630 aec79729cb3f18dd71d74d59ae70d4e0 438 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 337 366 3.5E-24 T 31-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TK0630 aec79729cb3f18dd71d74d59ae70d4e0 438 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 289 318 3.5E-24 T 31-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TK0630 aec79729cb3f18dd71d74d59ae70d4e0 438 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 260 287 3.5E-24 T 31-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TK0630 aec79729cb3f18dd71d74d59ae70d4e0 438 Gene3D G3DSA:1.10.287.950 123 435 4.3E-66 T 31-10-2018 TK0630 aec79729cb3f18dd71d74d59ae70d4e0 438 SMART SM00283 162 420 3.6E-67 T 31-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TK0232 a32b0e25bb0eefb5923b15fa019b8e4d 273 Gene3D G3DSA:3.40.630.30 1 189 1.7E-34 T 31-10-2018 TK0232 a32b0e25bb0eefb5923b15fa019b8e4d 273 Pfam PF00583 Acetyltransferase (GNAT) family 27 126 1.3E-13 T 31-10-2018 IPR000182 GNAT domain TK0232 a32b0e25bb0eefb5923b15fa019b8e4d 273 SUPERFAMILY SSF55729 1 136 2.36E-25 T 31-10-2018 IPR016181 Acyl-CoA N-acyltransferase TK0696 c91b05f31a18497ad611084b67104693 146 SMART SM00670 1 114 3.0E-10 T 31-10-2018 IPR002716 PIN domain TK0696 c91b05f31a18497ad611084b67104693 146 SUPERFAMILY SSF88723 1 115 1.57E-10 T 31-10-2018 IPR029060 PIN-like domain superfamily TK0696 c91b05f31a18497ad611084b67104693 146 TIGRFAM TIGR00305 TIGR00305: putative toxin-antitoxin system toxin component, PIN family 2 115 4.2E-22 T 31-10-2018 IPR002850 PIN family, putative toxin-antitoxin system toxin component TK0696 c91b05f31a18497ad611084b67104693 146 Pfam PF13470 PIN domain 2 109 1.1E-15 T 31-10-2018 IPR002716 PIN domain TK1025 9d855a74a84b2290980901bb93d5f074 292 Pfam PF16147 Domain of unknown function (DUF4855) 119 264 7.8E-9 T 31-10-2018 IPR032329 Protein of unknown function DUF4855 TK0472 57d57210227ace216043c66d8710c68c 70 Pfam PF13551 Winged helix-turn helix 5 45 7.9E-7 T 31-10-2018 TK0472 57d57210227ace216043c66d8710c68c 70 SUPERFAMILY SSF46785 5 51 6.3E-10 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TK0472 57d57210227ace216043c66d8710c68c 70 Gene3D G3DSA:1.10.10.10 1 70 3.2E-9 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TK0758 7a1ea4b6aa3143ec02eee158418b57dc 401 SUPERFAMILY SSF51338 12 399 4.32E-22 T 31-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 TK0758 7a1ea4b6aa3143ec02eee158418b57dc 401 Gene3D G3DSA:2.30.40.10 10 399 3.7E-119 T 31-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 TK0758 7a1ea4b6aa3143ec02eee158418b57dc 401 SUPERFAMILY SSF51556 54 344 2.37E-82 T 31-10-2018 IPR032466 Metal-dependent hydrolase TK0758 7a1ea4b6aa3143ec02eee158418b57dc 401 Pfam PF01979 Amidohydrolase family 51 395 1.5E-64 T 31-10-2018 IPR006680 Amidohydrolase-related GO:0016787 TK0758 7a1ea4b6aa3143ec02eee158418b57dc 401 Gene3D G3DSA:3.20.20.140 55 341 3.7E-119 T 31-10-2018 TK0222 d857ef3baa74311012d0bb1c02d37f5e 122 SUPERFAMILY SSF81301 31 115 3.54E-17 T 31-10-2018 TK0222 d857ef3baa74311012d0bb1c02d37f5e 122 Gene3D G3DSA:3.30.460.10 26 121 1.1E-17 T 31-10-2018 TK0222 d857ef3baa74311012d0bb1c02d37f5e 122 Pfam PF01909 Nucleotidyltransferase domain 32 92 9.9E-9 T 31-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 TK0907 6eb8188d7b226b52610d938c73a500cc 206 Gene3D G3DSA:1.20.58.2140 3 202 4.5E-67 T 31-10-2018 TK0907 6eb8188d7b226b52610d938c73a500cc 206 SUPERFAMILY SSF74784 2 182 5.1E-35 T 31-10-2018 IPR036081 Translin superfamily GO:0043565 Reactome: R-HSA-426486 TK0907 6eb8188d7b226b52610d938c73a500cc 206 Pfam PF01997 Translin family 47 181 3.9E-11 T 31-10-2018 IPR002848 Translin family GO:0043565 Reactome: R-HSA-426486 TK2118 a2defe877bc4dd4327cdc5a507ba42b4 88 SUPERFAMILY SSF54285 2 86 2.99E-25 T 31-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp TK2118 a2defe877bc4dd4327cdc5a507ba42b4 88 TIGRFAM TIGR01682 moaD: molybdopterin converting factor, subunit 1 3 88 6.8E-19 T 31-10-2018 TK2118 a2defe877bc4dd4327cdc5a507ba42b4 88 TIGRFAM TIGR01687 moaD_arch: MoaD family protein 3 88 1.3E-30 T 31-10-2018 IPR010038 MoaD, archaeal-type TK2118 a2defe877bc4dd4327cdc5a507ba42b4 88 Pfam PF02597 ThiS family 5 88 1.1E-23 T 31-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 TK2118 a2defe877bc4dd4327cdc5a507ba42b4 88 Gene3D G3DSA:3.10.20.30 1 88 7.6E-31 T 31-10-2018 IPR012675 Beta-grasp domain superfamily TK0507 ce47be338a42e256a8338ab0ceefb5c3 173 ProDom PD009560 CYCLASE ADENYLATE CYCLASE ADENYLYL CYAB LYASE CLASS CYAB-TYPE THERMOPHILIC MJ0240 2 141 2.0E-73 T 31-10-2018 TK0507 ce47be338a42e256a8338ab0ceefb5c3 173 SUPERFAMILY SSF55154 1 164 1.96E-39 T 31-10-2018 IPR033469 CYTH-like domain superfamily Reactome: R-HSA-196819 TK0507 ce47be338a42e256a8338ab0ceefb5c3 173 TIGRFAM TIGR00318 cyaB: putative adenylyl cyclase CyaB 1 165 1.4E-30 T 31-10-2018 IPR008173 Adenylyl cyclase CyaB KEGG: 00230+4.6.1.1 TK0507 ce47be338a42e256a8338ab0ceefb5c3 173 SMART SM01118 1 166 2.1E-12 T 31-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 TK0507 ce47be338a42e256a8338ab0ceefb5c3 173 Pfam PF01928 CYTH domain 2 160 2.1E-25 T 31-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 TK0507 ce47be338a42e256a8338ab0ceefb5c3 173 Gene3D G3DSA:2.40.320.10 1 172 3.7E-50 T 31-10-2018 TK2049 dd0a5b4f140b5e6af73d78af1fbb1e4a 622 Pfam PF00326 Prolyl oligopeptidase family 396 607 1.9E-53 T 31-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 TK2049 dd0a5b4f140b5e6af73d78af1fbb1e4a 622 SUPERFAMILY SSF53474 353 606 4.79E-58 T 31-10-2018 IPR029058 Alpha/Beta hydrolase fold TK2049 dd0a5b4f140b5e6af73d78af1fbb1e4a 622 Gene3D G3DSA:3.40.50.1820 353 622 1.4E-84 T 31-10-2018 IPR029058 Alpha/Beta hydrolase fold TK2049 dd0a5b4f140b5e6af73d78af1fbb1e4a 622 Gene3D G3DSA:2.120.10.30 21 200 2.6E-12 T 31-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like TK2049 dd0a5b4f140b5e6af73d78af1fbb1e4a 622 SUPERFAMILY SSF82171 24 340 9.42E-24 T 31-10-2018 TK1563 6be1b4fd93fa3b4eeb724da03b95f5ce 316 SUPERFAMILY SSF56024 178 312 6.73E-31 T 31-10-2018 TK1563 6be1b4fd93fa3b4eeb724da03b95f5ce 316 Pfam PF13091 PLD-like domain 184 311 2.3E-23 T 31-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 TK1563 6be1b4fd93fa3b4eeb724da03b95f5ce 316 Gene3D G3DSA:3.30.870.10 143 315 8.6E-37 T 31-10-2018 TK1563 6be1b4fd93fa3b4eeb724da03b95f5ce 316 SMART SM00155 259 286 1.1E-4 T 31-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 TK1865 682b3d62c8bade82736a30bad88bab3d 271 SUPERFAMILY SSF51658 1 234 1.96E-29 T 31-10-2018 IPR036237 Xylose isomerase-like superfamily TK1865 682b3d62c8bade82736a30bad88bab3d 271 Gene3D G3DSA:3.20.20.150 11 255 1.2E-35 T 31-10-2018 TK1865 682b3d62c8bade82736a30bad88bab3d 271 Pfam PF01261 Xylose isomerase-like TIM barrel 23 214 3.6E-24 T 31-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain TK1299 3e4bc8999dc01e272bd97b4443990b5c 442 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 302 6.5E-57 T 31-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TK1299 3e4bc8999dc01e272bd97b4443990b5c 442 SUPERFAMILY SSF51905 1 345 2.27E-48 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TK1299 3e4bc8999dc01e272bd97b4443990b5c 442 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 327 428 2.3E-18 T 31-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 TK1299 3e4bc8999dc01e272bd97b4443990b5c 442 TIGRFAM TIGR03385 CoA_CoA_reduc: CoA-disulfide reductase 6 437 5.3E-184 T 31-10-2018 IPR017758 Coenzyme A disulphide reductase GO:0003756|GO:0050451|GO:0050660|GO:0050661|GO:0055114 TK1299 3e4bc8999dc01e272bd97b4443990b5c 442 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 260 282 9.9E-27 T 31-10-2018 TK1299 3e4bc8999dc01e272bd97b4443990b5c 442 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 233 249 9.9E-27 T 31-10-2018 TK1299 3e4bc8999dc01e272bd97b4443990b5c 442 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 9.9E-27 T 31-10-2018 TK1299 3e4bc8999dc01e272bd97b4443990b5c 442 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 150 168 9.9E-27 T 31-10-2018 TK1299 3e4bc8999dc01e272bd97b4443990b5c 442 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 103 121 9.9E-27 T 31-10-2018 TK1299 3e4bc8999dc01e272bd97b4443990b5c 442 SUPERFAMILY SSF55424 321 439 2.23E-30 T 31-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 TK1299 3e4bc8999dc01e272bd97b4443990b5c 442 Gene3D G3DSA:3.50.50.60 6 315 4.2E-114 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TK1299 3e4bc8999dc01e272bd97b4443990b5c 442 Gene3D G3DSA:3.50.50.60 321 442 1.9E-44 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TK1299 3e4bc8999dc01e272bd97b4443990b5c 442 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 150 175 8.5E-22 T 31-10-2018 TK1299 3e4bc8999dc01e272bd97b4443990b5c 442 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 8.5E-22 T 31-10-2018 TK1299 3e4bc8999dc01e272bd97b4443990b5c 442 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 234 248 8.5E-22 T 31-10-2018 TK1299 3e4bc8999dc01e272bd97b4443990b5c 442 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 275 282 8.5E-22 T 31-10-2018 TK1299 3e4bc8999dc01e272bd97b4443990b5c 442 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 385 400 8.5E-22 T 31-10-2018 TK1299 3e4bc8999dc01e272bd97b4443990b5c 442 Gene3D G3DSA:3.50.50.60 44 242 4.2E-114 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TK0019 0d1d87f800d445f65502f14234683ab2 339 PIRSF PIRSF029347 189 331 0.0025 T 31-10-2018 IPR014555 RecF-like TK0019 0d1d87f800d445f65502f14234683ab2 339 PIRSF PIRSF029347 1 108 1.3E-10 T 31-10-2018 IPR014555 RecF-like TK0019 0d1d87f800d445f65502f14234683ab2 339 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 24 291 1.6E-15 T 31-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TK0019 0d1d87f800d445f65502f14234683ab2 339 SUPERFAMILY SSF52540 1 309 4.64E-19 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK0019 0d1d87f800d445f65502f14234683ab2 339 Gene3D G3DSA:3.40.50.300 1 328 2.4E-17 T 31-10-2018 TK1085 8cb344c29aab0a7f0535f294b9a83d53 226 Gene3D G3DSA:3.40.30.10 1 117 4.9E-39 T 31-10-2018 TK1085 8cb344c29aab0a7f0535f294b9a83d53 226 SUPERFAMILY SSF52833 5 117 5.96E-26 T 31-10-2018 IPR036249 Thioredoxin-like superfamily TK1085 8cb344c29aab0a7f0535f294b9a83d53 226 Pfam PF00085 Thioredoxin 12 94 3.4E-5 T 31-10-2018 IPR013766 Thioredoxin domain GO:0045454 TK1085 8cb344c29aab0a7f0535f294b9a83d53 226 Pfam PF13192 Thioredoxin domain 137 222 2.2E-14 T 31-10-2018 IPR012336 Thioredoxin-like fold TK1085 8cb344c29aab0a7f0535f294b9a83d53 226 Gene3D G3DSA:3.40.30.10 121 225 2.0E-25 T 31-10-2018 TK1085 8cb344c29aab0a7f0535f294b9a83d53 226 TIGRFAM TIGR02187 GlrX_arch: glutaredoxin-like domain protein 4 223 2.6E-90 T 31-10-2018 IPR011903 Glutaredoxin-like domain TK1085 8cb344c29aab0a7f0535f294b9a83d53 226 SUPERFAMILY SSF52833 124 222 5.46E-20 T 31-10-2018 IPR036249 Thioredoxin-like superfamily TK2114 9a146e9e48df903149f252db1d3b432a 310 SUPERFAMILY SSF102114 210 283 1.33E-11 T 31-10-2018 TK2114 9a146e9e48df903149f252db1d3b432a 310 Gene3D G3DSA:3.20.20.70 117 308 1.6E-11 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TK2114 9a146e9e48df903149f252db1d3b432a 310 Pfam PF13186 Iron-sulfur cluster-binding domain 222 278 4.1E-8 T 31-10-2018 IPR023885 4Fe4S-binding SPASM domain TK2114 9a146e9e48df903149f252db1d3b432a 310 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 219 299 9.9E-11 T 31-10-2018 IPR023885 4Fe4S-binding SPASM domain TK2026 81a581173b2103a3017764b85d56ce48 322 Pfam PF00005 ABC transporter 31 174 1.3E-29 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TK2026 81a581173b2103a3017764b85d56ce48 322 SMART SM00382 39 232 5.8E-16 T 31-10-2018 IPR003593 AAA+ ATPase domain TK2026 81a581173b2103a3017764b85d56ce48 322 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 27 317 3.4E-101 T 31-10-2018 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 TK2026 81a581173b2103a3017764b85d56ce48 322 SUPERFAMILY SSF52540 4 235 6.76E-61 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK2026 81a581173b2103a3017764b85d56ce48 322 Pfam PF13732 Domain of unknown function (DUF4162) 242 316 7.3E-7 T 31-10-2018 IPR025302 Domain of unknown function DUF4162 TK2026 81a581173b2103a3017764b85d56ce48 322 Gene3D G3DSA:3.40.50.300 1 251 2.1E-66 T 31-10-2018 TK1142 777115c088df6cca9ef98593d3055d77 142 Pfam PF02933 Cell division protein 48 (CDC48), domain 2 14 72 5.4E-7 T 31-10-2018 IPR004201 CDC48, domain 2 TK1142 777115c088df6cca9ef98593d3055d77 142 Gene3D G3DSA:2.40.10.360 80 141 4.6E-13 T 31-10-2018 TK1142 777115c088df6cca9ef98593d3055d77 142 Gene3D G3DSA:3.10.330.10 1 78 1.8E-27 T 31-10-2018 TK1142 777115c088df6cca9ef98593d3055d77 142 SMART SM01072 12 74 5.0E-9 T 31-10-2018 IPR004201 CDC48, domain 2 TK1142 777115c088df6cca9ef98593d3055d77 142 SUPERFAMILY SSF54585 2 78 2.29E-14 T 31-10-2018 IPR029067 CDC48 domain 2-like superfamily TK1581 0b8e3163edf113973032f435d228d959 169 Gene3D G3DSA:3.10.450.220 1 95 2.7E-46 T 31-10-2018 TK1581 0b8e3163edf113973032f435d228d959 169 Gene3D G3DSA:2.30.130.10 96 167 5.2E-20 T 31-10-2018 IPR036974 PUA domain superfamily GO:0003723 TK1581 0b8e3163edf113973032f435d228d959 169 Pfam PF03657 Uncharacterised protein family (UPF0113) 7 167 7.0E-11 T 31-10-2018 IPR005155 Ribosome biogenesis factor NIP7-like Reactome: R-HSA-6791226 TK1676 dfe814ec475197f233628b01b7702992 390 Gene3D G3DSA:3.90.1170.20 1 106 1.5E-45 T 31-10-2018 IPR037128 Quinolinate phosphoribosyl transferase, N-terminal domain superfamily GO:0016763 Reactome: R-HSA-196807 TK1676 dfe814ec475197f233628b01b7702992 390 Gene3D G3DSA:3.20.140.10 299 389 9.0E-7 T 31-10-2018 TK1676 dfe814ec475197f233628b01b7702992 390 SUPERFAMILY SSF51690 112 387 4.45E-77 T 31-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 TK1676 dfe814ec475197f233628b01b7702992 390 SUPERFAMILY SSF54675 2 115 5.63E-33 T 31-10-2018 TK1676 dfe814ec475197f233628b01b7702992 390 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 53 113 1.0E-5 T 31-10-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 TK1676 dfe814ec475197f233628b01b7702992 390 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 115 303 6.7E-28 T 31-10-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 Reactome: R-HSA-196807 TK1676 dfe814ec475197f233628b01b7702992 390 PIRSF PIRSF000484 58 388 2.0E-49 T 31-10-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 TK1676 dfe814ec475197f233628b01b7702992 390 PIRSF PIRSF000484 12 71 38.0 T 31-10-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 TK1676 dfe814ec475197f233628b01b7702992 390 Gene3D G3DSA:3.20.20.70 107 297 8.6E-65 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TK1984 b64ed7603d4ba019b10092c361e1fae9 331 Gene3D G3DSA:3.40.50.970 98 323 1.7E-68 T 31-10-2018 TK1984 b64ed7603d4ba019b10092c361e1fae9 331 Gene3D G3DSA:3.40.50.970 12 97 7.5E-11 T 31-10-2018 TK1984 b64ed7603d4ba019b10092c361e1fae9 331 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 57 218 3.5E-26 T 31-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 TK1984 b64ed7603d4ba019b10092c361e1fae9 331 SUPERFAMILY SSF52518 12 317 6.22E-76 T 31-10-2018 IPR029061 Thiamin diphosphate-binding fold TK0674 56223e4f9f783198536376b54cf0dd61 148 SUPERFAMILY SSF81301 16 97 4.76E-13 T 31-10-2018 TK0674 56223e4f9f783198536376b54cf0dd61 148 Gene3D G3DSA:3.30.460.10 13 123 2.4E-8 T 31-10-2018 TK0674 56223e4f9f783198536376b54cf0dd61 148 Pfam PF01909 Nucleotidyltransferase domain 27 96 3.1E-7 T 31-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 TK0515 b35caa00ce1122b5d4bbc031c2e7f713 126 Pfam PF02641 Uncharacterized ACR, COG1993 11 105 1.4E-39 T 31-10-2018 IPR003793 Domain of unknown function DUF190 TK0515 b35caa00ce1122b5d4bbc031c2e7f713 126 SUPERFAMILY SSF54913 8 107 2.41E-34 T 31-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta TK0515 b35caa00ce1122b5d4bbc031c2e7f713 126 Gene3D G3DSA:3.30.70.120 1 126 2.3E-58 T 31-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal TK1032 e8a37500ed4611bab34643574c132018 330 PIRSF PIRSF005644 5 328 4.4E-88 T 31-10-2018 IPR011854 Carbamoyl dehydratase HypE TK1032 e8a37500ed4611bab34643574c132018 330 SUPERFAMILY SSF55326 6 143 1.2E-25 T 31-10-2018 IPR036921 PurM-like, N-terminal domain superfamily TK1032 e8a37500ed4611bab34643574c132018 330 SUPERFAMILY SSF56042 145 317 6.28E-36 T 31-10-2018 IPR036676 PurM-like, C-terminal domain superfamily TK1032 e8a37500ed4611bab34643574c132018 330 Gene3D G3DSA:3.90.650.10 144 328 7.8E-50 T 31-10-2018 IPR036676 PurM-like, C-terminal domain superfamily TK1032 e8a37500ed4611bab34643574c132018 330 Pfam PF02769 AIR synthase related protein, C-terminal domain 151 308 7.0E-25 T 31-10-2018 IPR010918 PurM-like, C-terminal domain TK1032 e8a37500ed4611bab34643574c132018 330 Pfam PF00586 AIR synthase related protein, N-terminal domain 47 139 4.9E-16 T 31-10-2018 IPR016188 PurM-like, N-terminal domain TK1032 e8a37500ed4611bab34643574c132018 330 Gene3D G3DSA:3.30.1330.10 7 143 7.6E-30 T 31-10-2018 IPR036921 PurM-like, N-terminal domain superfamily TK0728 96aff058092a41a98100b8a3ee4a9aa5 385 Gene3D G3DSA:2.130.10.10 30 320 2.1E-21 T 31-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 TK0728 96aff058092a41a98100b8a3ee4a9aa5 385 Pfam PF13360 PQQ-like domain 155 283 1.3E-7 T 31-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat TK0728 96aff058092a41a98100b8a3ee4a9aa5 385 SUPERFAMILY SSF50998 63 320 1.02E-24 T 31-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily TK0141 8fedf5268e4d299b2f2db6e6c6ce5522 224 Pfam PF13483 Beta-lactamase superfamily domain 3 189 7.7E-33 T 31-10-2018 TK0141 8fedf5268e4d299b2f2db6e6c6ce5522 224 Hamap MF_00457 UPF0173 metal-dependent hydrolase . 2 224 39.003 T 31-10-2018 IPR022877 Protein of unknown funcion UPF0173 TK0141 8fedf5268e4d299b2f2db6e6c6ce5522 224 Gene3D G3DSA:3.60.15.10 2 224 7.3E-73 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TK0141 8fedf5268e4d299b2f2db6e6c6ce5522 224 SMART SM00849 8 189 3.5E-17 T 31-10-2018 IPR001279 Metallo-beta-lactamase TK0141 8fedf5268e4d299b2f2db6e6c6ce5522 224 SUPERFAMILY SSF56281 1 220 2.75E-39 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TK0880 c26e408809a2b6d971fb0662793120f9 426 Pfam PF03600 Citrate transporter 17 366 4.9E-57 T 31-10-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 TK0880 c26e408809a2b6d971fb0662793120f9 426 PRINTS PR00758 Arsenical pump membrane protein signature 278 302 1.9E-17 T 31-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 TK0880 c26e408809a2b6d971fb0662793120f9 426 PRINTS PR00758 Arsenical pump membrane protein signature 322 344 1.9E-17 T 31-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 TK0880 c26e408809a2b6d971fb0662793120f9 426 PRINTS PR00758 Arsenical pump membrane protein signature 101 125 1.9E-17 T 31-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 TK0880 c26e408809a2b6d971fb0662793120f9 426 PRINTS PR00758 Arsenical pump membrane protein signature 395 419 1.9E-17 T 31-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 TK0880 c26e408809a2b6d971fb0662793120f9 426 PRINTS PR00758 Arsenical pump membrane protein signature 221 246 1.9E-17 T 31-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 TK0880 c26e408809a2b6d971fb0662793120f9 426 PRINTS PR00758 Arsenical pump membrane protein signature 362 387 1.9E-17 T 31-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 TK0838 2b6b03bea206a9016a0a0e9322348a7a 101 ProSitePatterns PS00194 Thioredoxin family active site. 17 35 - T 31-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 TK0838 2b6b03bea206a9016a0a0e9322348a7a 101 Pfam PF00085 Thioredoxin 4 87 1.3E-12 T 31-10-2018 IPR013766 Thioredoxin domain GO:0045454 TK0838 2b6b03bea206a9016a0a0e9322348a7a 101 SUPERFAMILY SSF52833 10 83 4.2E-18 T 31-10-2018 IPR036249 Thioredoxin-like superfamily TK0838 2b6b03bea206a9016a0a0e9322348a7a 101 Gene3D G3DSA:3.40.30.10 3 94 6.3E-15 T 31-10-2018 TK0481 83c57d496b109a654b8f4e4386496663 170 Gene3D G3DSA:3.30.300.20 47 97 2.0E-8 T 31-10-2018 IPR015946 K homology domain-like, alpha/beta TK0481 83c57d496b109a654b8f4e4386496663 170 SMART SM00322 57 158 0.0019 T 31-10-2018 IPR004087 K Homology domain GO:0003676 TK0481 83c57d496b109a654b8f4e4386496663 170 Pfam PF13184 NusA-like KH domain 57 124 9.8E-10 T 31-10-2018 IPR025249 KH domain, NusA-like GO:0003723 TK0481 83c57d496b109a654b8f4e4386496663 170 SUPERFAMILY SSF54814 38 96 5.69E-9 T 31-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 TK1811 6c0dd365197a3c36fc3687694dede1bb 231 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 96 188 5.1E-10 T 31-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TK1811 6c0dd365197a3c36fc3687694dede1bb 231 Gene3D G3DSA:3.40.50.1000 3 216 1.9E-36 T 31-10-2018 IPR023214 HAD superfamily TK1811 6c0dd365197a3c36fc3687694dede1bb 231 Gene3D G3DSA:1.10.150.520 14 96 1.9E-36 T 31-10-2018 TK1811 6c0dd365197a3c36fc3687694dede1bb 231 Pfam PF13419 Haloacid dehalogenase-like hydrolase 3 194 4.4E-21 T 31-10-2018 TK1811 6c0dd365197a3c36fc3687694dede1bb 231 SUPERFAMILY SSF56784 3 222 3.87E-37 T 31-10-2018 IPR036412 HAD-like superfamily TK0890 4380f15ebfeb7831cba204805c16100a 309 PIRSF PIRSF005303 1 305 6.1E-93 T 31-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 TK0890 4380f15ebfeb7831cba204805c16100a 309 TIGRFAM TIGR01379 thiL: thiamine-phosphate kinase 3 305 1.3E-86 T 31-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 TK0890 4380f15ebfeb7831cba204805c16100a 309 Gene3D G3DSA:3.90.650.10 139 305 7.8E-49 T 31-10-2018 IPR036676 PurM-like, C-terminal domain superfamily TK0890 4380f15ebfeb7831cba204805c16100a 309 SUPERFAMILY SSF55326 13 133 9.94E-32 T 31-10-2018 IPR036921 PurM-like, N-terminal domain superfamily TK0890 4380f15ebfeb7831cba204805c16100a 309 Hamap MF_02128 Thiamine-monophosphate kinase [thiL]. 1 305 29.001 T 31-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 TK0890 4380f15ebfeb7831cba204805c16100a 309 Gene3D G3DSA:3.30.1330.10 1 138 3.8E-36 T 31-10-2018 IPR036921 PurM-like, N-terminal domain superfamily TK0890 4380f15ebfeb7831cba204805c16100a 309 Pfam PF02769 AIR synthase related protein, C-terminal domain 144 291 2.0E-9 T 31-10-2018 IPR010918 PurM-like, C-terminal domain TK0890 4380f15ebfeb7831cba204805c16100a 309 Pfam PF00586 AIR synthase related protein, N-terminal domain 24 133 1.3E-17 T 31-10-2018 IPR016188 PurM-like, N-terminal domain TK0890 4380f15ebfeb7831cba204805c16100a 309 SUPERFAMILY SSF56042 137 292 1.2E-39 T 31-10-2018 IPR036676 PurM-like, C-terminal domain superfamily TK0557 4fdf30181ce03e63b1fe5a1061d19292 180 SUPERFAMILY SSF52540 5 168 2.35E-23 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK0557 4fdf30181ce03e63b1fe5a1061d19292 180 Hamap MF_00796 Nucleoside-triphosphatase . 3 175 29.763 T 31-10-2018 IPR004948 Nucleoside-triphosphatase, THEP1 type GO:0098519 KEGG: 00230+3.6.1.15|KEGG: 00730+3.6.1.15|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210 TK0557 4fdf30181ce03e63b1fe5a1061d19292 180 SMART SM00382 1 158 1.7E-5 T 31-10-2018 IPR003593 AAA+ ATPase domain TK0557 4fdf30181ce03e63b1fe5a1061d19292 180 Pfam PF03266 NTPase 4 167 3.1E-56 T 31-10-2018 IPR004948 Nucleoside-triphosphatase, THEP1 type GO:0098519 KEGG: 00230+3.6.1.15|KEGG: 00730+3.6.1.15|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210 TK0557 4fdf30181ce03e63b1fe5a1061d19292 180 Gene3D G3DSA:3.40.50.300 3 175 3.1E-42 T 31-10-2018 TK1430 b98f73a5e42aa55ed4fdc8d0ea02d36c 388 Gene3D G3DSA:3.40.50.300 1 184 4.0E-13 T 31-10-2018 TK0277 ea65ab7384efa9b6b6adfc7422c1089c 330 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 3 134 1.1E-28 T 31-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 TK0277 ea65ab7384efa9b6b6adfc7422c1089c 330 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 204 300 4.8E-6 T 31-10-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0005737|GO:0008652|GO:0016620|GO:0046983 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 TK0277 ea65ab7384efa9b6b6adfc7422c1089c 330 SMART SM00859 3 134 2.9E-51 T 31-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 TK0277 ea65ab7384efa9b6b6adfc7422c1089c 330 TIGRFAM TIGR01850 argC: N-acetyl-gamma-glutamyl-phosphate reductase 2 329 1.8E-114 T 31-10-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 TK0277 ea65ab7384efa9b6b6adfc7422c1089c 330 Hamap MF_02083 [LysW]-L-2-aminoadipate/[LysW]-L-glutamate phosphate reductase [lysY]. 2 329 47.401 T 31-10-2018 IPR037535 [LysW]-L-2-aminoadipate/[LysW]-L-glutamate phosphate reductase GO:0016620 TK0277 ea65ab7384efa9b6b6adfc7422c1089c 330 Gene3D G3DSA:3.40.50.720 5 315 9.7E-103 T 31-10-2018 TK0277 ea65ab7384efa9b6b6adfc7422c1089c 330 SUPERFAMILY SSF51735 1 155 1.27E-48 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily TK0277 ea65ab7384efa9b6b6adfc7422c1089c 330 ProSitePatterns PS01224 N-acetyl-gamma-glutamyl-phosphate reductase active site. 137 153 - T 31-10-2018 IPR023013 N-acetyl-gamma-glutamyl-phosphate reductase, active site GO:0003942|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 TK0277 ea65ab7384efa9b6b6adfc7422c1089c 330 Hamap MF_00150 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 2 323 39.136 T 31-10-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 TK0277 ea65ab7384efa9b6b6adfc7422c1089c 330 SUPERFAMILY SSF55347 142 297 2.22E-31 T 31-10-2018 TK0277 ea65ab7384efa9b6b6adfc7422c1089c 330 Gene3D G3DSA:3.30.360.10 140 301 9.7E-103 T 31-10-2018 TK0798 47533cab5dfc04e22d372f62db731de2 385 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 106 117 2.8E-29 T 31-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 TK0798 47533cab5dfc04e22d372f62db731de2 385 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 201 218 2.8E-29 T 31-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 TK0798 47533cab5dfc04e22d372f62db731de2 385 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 146 161 2.8E-29 T 31-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 TK0798 47533cab5dfc04e22d372f62db731de2 385 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 257 273 2.8E-29 T 31-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 TK0798 47533cab5dfc04e22d372f62db731de2 385 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 128 145 2.8E-29 T 31-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 TK0798 47533cab5dfc04e22d372f62db731de2 385 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 225 246 2.8E-29 T 31-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 TK0798 47533cab5dfc04e22d372f62db731de2 385 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 122 139 3.0E-49 T 31-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 TK0798 47533cab5dfc04e22d372f62db731de2 385 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 355 378 3.0E-49 T 31-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 TK0798 47533cab5dfc04e22d372f62db731de2 385 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 231 251 3.0E-49 T 31-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 TK0798 47533cab5dfc04e22d372f62db731de2 385 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 48 68 3.0E-49 T 31-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 TK0798 47533cab5dfc04e22d372f62db731de2 385 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 175 193 3.0E-49 T 31-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 TK0798 47533cab5dfc04e22d372f62db731de2 385 Pfam PF04406 Type IIB DNA topoisomerase 82 151 1.9E-19 T 31-10-2018 IPR013049 Spo11/DNA topoisomerase VI, subunit A, N-terminal GO:0003677|GO:0003824|GO:0005524|GO:0005694|GO:0006259 Reactome: R-HSA-912446 TK0798 47533cab5dfc04e22d372f62db731de2 385 SUPERFAMILY SSF56726 80 383 4.18E-79 T 31-10-2018 IPR036078 Spo11/DNA topoisomerase VI subunit A superfamily GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 TK0798 47533cab5dfc04e22d372f62db731de2 385 Hamap MF_00132 Type 2 DNA topoisomerase 6 subunit A [top6A]. 16 384 40.235 T 31-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 TK0798 47533cab5dfc04e22d372f62db731de2 385 Gene3D G3DSA:3.40.1360.10 155 384 8.4E-65 T 31-10-2018 TK0798 47533cab5dfc04e22d372f62db731de2 385 Gene3D G3DSA:1.10.10.10 11 154 7.9E-53 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TK1475 6f29d6b1eac632b2253f149b889ffd20 140 Pfam PF01934 Protein of unknown function DUF86 13 132 1.3E-25 T 31-10-2018 IPR008201 Protein of unknown function DUF86 TK1475 6f29d6b1eac632b2253f149b889ffd20 140 Gene3D G3DSA:1.20.120.580 4 140 1.8E-17 T 31-10-2018 IPR037038 Bsu32300-like superfamily TK1226 c3e5d277958012b62797d069d18fb1ac 177 Pfam PF01899 Na+/H+ ion antiporter subunit 15 173 2.2E-46 T 31-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 TK1226 c3e5d277958012b62797d069d18fb1ac 177 PIRSF PIRSF019239 4 177 1.1E-56 T 31-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 TK1757 0e18f932ab37faf4a8f2ac53c5a53aec 325 ProSitePatterns PS00211 ABC transporters family signature. 152 166 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TK1757 0e18f932ab37faf4a8f2ac53c5a53aec 325 Gene3D G3DSA:3.40.50.300 1 325 4.2E-85 T 31-10-2018 TK1757 0e18f932ab37faf4a8f2ac53c5a53aec 325 SMART SM00382 33 230 8.4E-11 T 31-10-2018 IPR003593 AAA+ ATPase domain TK1757 0e18f932ab37faf4a8f2ac53c5a53aec 325 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 230 318 1.4E-25 T 31-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TK1757 0e18f932ab37faf4a8f2ac53c5a53aec 325 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 233 298 8.9E-20 T 31-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TK1757 0e18f932ab37faf4a8f2ac53c5a53aec 325 Pfam PF00005 ABC transporter 25 180 6.7E-23 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TK1757 0e18f932ab37faf4a8f2ac53c5a53aec 325 SUPERFAMILY SSF52540 4 264 8.67E-54 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK1717 89e015d00f5a0eebae63648ebacdbe3a 294 SUPERFAMILY SSF53448 3 214 5.63E-60 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TK1717 89e015d00f5a0eebae63648ebacdbe3a 294 Pfam PF00535 Glycosyl transferase family 2 6 129 9.4E-29 T 31-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TK1717 89e015d00f5a0eebae63648ebacdbe3a 294 Gene3D G3DSA:3.90.550.10 1 234 1.4E-63 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TK2143 13cdf161e2f92a81687d8cdea062fe63 196 SMART SM00986 33 187 3.6E-39 T 31-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 TK2143 13cdf161e2f92a81687d8cdea062fe63 196 SUPERFAMILY SSF52141 9 194 2.19E-63 T 31-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 TK2143 13cdf161e2f92a81687d8cdea062fe63 196 Pfam PF03167 Uracil DNA glycosylase superfamily 33 186 2.3E-47 T 31-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 TK2143 13cdf161e2f92a81687d8cdea062fe63 196 TIGRFAM TIGR00758 UDG_fam4: uracil-DNA glycosylase, family 4 19 194 4.2E-77 T 31-10-2018 IPR005273 Uracil-DNA glycosylase family 4 TK2143 13cdf161e2f92a81687d8cdea062fe63 196 Gene3D G3DSA:3.40.470.10 7 194 2.4E-72 T 31-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 TK2143 13cdf161e2f92a81687d8cdea062fe63 196 SMART SM00987 33 187 3.6E-39 T 31-10-2018 TK0558 14d116192037952fc313b39f0b075c63 177 Pfam PF00571 CBS domain 6 60 5.4E-13 T 31-10-2018 IPR000644 CBS domain TK0558 14d116192037952fc313b39f0b075c63 177 Pfam PF00571 CBS domain 72 125 3.1E-13 T 31-10-2018 IPR000644 CBS domain TK0558 14d116192037952fc313b39f0b075c63 177 Gene3D G3DSA:3.10.580.10 1 176 8.8E-43 T 31-10-2018 TK0558 14d116192037952fc313b39f0b075c63 177 SUPERFAMILY SSF54631 3 133 5.43E-33 T 31-10-2018 TK0558 14d116192037952fc313b39f0b075c63 177 SMART SM00116 79 126 1.0E-8 T 31-10-2018 IPR000644 CBS domain TK0558 14d116192037952fc313b39f0b075c63 177 SMART SM00116 13 61 2.2E-9 T 31-10-2018 IPR000644 CBS domain TK0687 23c60b30332647155e4d500a69f2faa8 193 Pfam PF04266 ASCH domain 15 113 1.8E-21 T 31-10-2018 IPR007374 ASCH domain TK0687 23c60b30332647155e4d500a69f2faa8 193 SMART SM01022 12 113 2.8E-20 T 31-10-2018 IPR007374 ASCH domain TK0687 23c60b30332647155e4d500a69f2faa8 193 SUPERFAMILY SSF88697 9 112 1.49E-20 T 31-10-2018 IPR015947 PUA-like superfamily TK0642 c4129402f7e0282a72fa907b3d90cd65 82 Pfam PF09341 Transcription factor Pcc1 9 80 2.3E-13 T 31-10-2018 IPR015419 CTAG/Pcc1 family TK0642 c4129402f7e0282a72fa907b3d90cd65 82 Gene3D G3DSA:3.30.310.50 1 82 1.2E-24 T 31-10-2018 TK2004 01867648785effd58a85da3e879eda71 158 SUPERFAMILY SSF53163 13 157 6.41E-30 T 31-10-2018 IPR023430 Peptidase HybD-like domain superfamily TK2004 01867648785effd58a85da3e879eda71 158 PRINTS PR00446 Hydrogen uptake protein signature 26 37 9.9E-6 T 31-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 TK2004 01867648785effd58a85da3e879eda71 158 PRINTS PR00446 Hydrogen uptake protein signature 68 78 9.9E-6 T 31-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 TK2004 01867648785effd58a85da3e879eda71 158 PRINTS PR00446 Hydrogen uptake protein signature 14 26 9.9E-6 T 31-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 TK2004 01867648785effd58a85da3e879eda71 158 TIGRFAM TIGR00072 hydrog_prot: hydrogenase maturation protease 15 154 3.7E-32 T 31-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 TK2004 01867648785effd58a85da3e879eda71 158 Gene3D G3DSA:3.40.50.1450 10 158 1.3E-40 T 31-10-2018 IPR023430 Peptidase HybD-like domain superfamily TK2004 01867648785effd58a85da3e879eda71 158 Pfam PF01750 Hydrogenase maturation protease 31 153 1.1E-13 T 31-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 TK1326 e7e8010051b799f7d74dd40a9fc3469c 291 SUPERFAMILY SSF63380 2 94 1.02E-17 T 31-10-2018 IPR017938 Riboflavin synthase-like beta-barrel TK1326 e7e8010051b799f7d74dd40a9fc3469c 291 Gene3D G3DSA:3.40.50.80 101 212 3.3E-17 T 31-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain TK1326 e7e8010051b799f7d74dd40a9fc3469c 291 PIRSF PIRSF006816 1 264 2.4E-56 T 31-10-2018 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 TK1326 e7e8010051b799f7d74dd40a9fc3469c 291 SUPERFAMILY SSF52343 90 257 1.37E-13 T 31-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain TK1326 e7e8010051b799f7d74dd40a9fc3469c 291 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 222 258 3.8E-10 T 31-10-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain TK1326 e7e8010051b799f7d74dd40a9fc3469c 291 Gene3D G3DSA:2.40.30.10 1 93 2.8E-17 T 31-10-2018 TK1912 6d68e65657397b67599033f23c5f8255 561 Gene3D G3DSA:3.40.630.10 28 401 2.3E-51 T 31-10-2018 TK1912 6d68e65657397b67599033f23c5f8255 561 Pfam PF04389 Peptidase family M28 226 408 2.5E-17 T 31-10-2018 IPR007484 Peptidase M28 TK1912 6d68e65657397b67599033f23c5f8255 561 Gene3D G3DSA:3.50.30.30 71 206 2.3E-51 T 31-10-2018 TK1912 6d68e65657397b67599033f23c5f8255 561 SUPERFAMILY SSF53187 10 415 1.45E-30 T 31-10-2018 TK1869 e82083be400ba6c15948a52f29cf95ae 201 SUPERFAMILY SSF109755 5 188 1.67E-16 T 31-10-2018 TK1869 e82083be400ba6c15948a52f29cf95ae 201 Gene3D G3DSA:1.20.58.220 3 191 8.6E-8 T 31-10-2018 IPR038078 PhoU-like domain superfamily TK0705 351fc583c7f98f03f802ac89538fba64 507 Gene3D G3DSA:3.40.605.10 37 270 1.1E-130 T 31-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 TK0705 351fc583c7f98f03f802ac89538fba64 507 SUPERFAMILY SSF53720 22 500 2.62E-135 T 31-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 TK0705 351fc583c7f98f03f802ac89538fba64 507 Pfam PF00171 Aldehyde dehydrogenase family 38 494 2.9E-123 T 31-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 TK0705 351fc583c7f98f03f802ac89538fba64 507 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 268 275 - T 31-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 TK0705 351fc583c7f98f03f802ac89538fba64 507 Gene3D G3DSA:3.40.309.10 271 470 1.1E-130 T 31-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 TK1425 85e2a20d957d6cd0204a3bc609090392 198 TIGRFAM TIGR03875 RNA_lig_partner: RNA ligase partner, MJ_0950 family 2 189 4.5E-71 T 31-10-2018 IPR014856 PIN-domain ribonuclease TK1425 85e2a20d957d6cd0204a3bc609090392 198 Hamap MF_01078 UPF0278 protein . 1 193 29.519 T 31-10-2018 IPR014856 PIN-domain ribonuclease TK1425 85e2a20d957d6cd0204a3bc609090392 198 Pfam PF08745 PINc domain ribonuclease 2 190 3.2E-66 T 31-10-2018 IPR014856 PIN-domain ribonuclease TK1425 85e2a20d957d6cd0204a3bc609090392 198 SUPERFAMILY SSF88723 70 178 4.77E-7 T 31-10-2018 IPR029060 PIN-like domain superfamily TK0495 97421e9faef8f7f450313e14961d4b77 420 Pfam PF07282 Putative transposase DNA-binding domain 314 383 1.6E-20 T 31-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal TK0495 97421e9faef8f7f450313e14961d4b77 420 Pfam PF01385 Probable transposase 169 294 2.6E-37 T 31-10-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 TK0495 97421e9faef8f7f450313e14961d4b77 420 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 264 341 6.3E-9 T 31-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal TK1297 42c37b9270e8346ab571fc234d64a82a 390 Gene3D G3DSA:2.40.50.140 332 385 2.8E-8 T 31-10-2018 TK1297 42c37b9270e8346ab571fc234d64a82a 390 SUPERFAMILY SSF50249 332 382 7.28E-6 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold TK1297 42c37b9270e8346ab571fc234d64a82a 390 Pfam PF04981 NMD3 family 6 276 1.4E-66 T 31-10-2018 IPR007064 Nmd3, N-terminal TK0548 74025586bca45f621990c98dc2884aec 389 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 230 243 - T 31-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 TK0548 74025586bca45f621990c98dc2884aec 389 SUPERFAMILY SSF53383 2 385 1.33E-124 T 31-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TK0548 74025586bca45f621990c98dc2884aec 389 Gene3D G3DSA:3.40.640.10 58 280 1.2E-152 T 31-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TK0548 74025586bca45f621990c98dc2884aec 389 Pfam PF00155 Aminotransferase class I and II 27 378 1.6E-78 T 31-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 TK0548 74025586bca45f621990c98dc2884aec 389 Gene3D G3DSA:3.90.1150.10 27 378 1.2E-152 T 31-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TK2085 bd62b28f171b47460366e36d7aa74bca 149 Pfam PF04039 Domain related to MnhB subunit of Na+/H+ antiporter 9 135 3.3E-26 T 31-10-2018 IPR007182 Na+/H+ antiporter MnhB subunit-related protein TK0700 1f3f6d76de1a0fb9c90e27dcab55f9f8 97 Gene3D G3DSA:1.10.287.1080 1 79 1.3E-28 T 31-10-2018 TK0700 1f3f6d76de1a0fb9c90e27dcab55f9f8 97 SUPERFAMILY SSF101386 1 79 1.8E-21 T 31-10-2018 TK0700 1f3f6d76de1a0fb9c90e27dcab55f9f8 97 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 24 82 2.1E-14 T 31-10-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core TK1934 4e690cbf8ab406da7a3a734135b998d7 309 SUPERFAMILY SSF48371 23 245 3.02E-7 T 31-10-2018 IPR016024 Armadillo-type fold TK1934 4e690cbf8ab406da7a3a734135b998d7 309 Gene3D G3DSA:1.25.10.10 1 245 6.3E-28 T 31-10-2018 IPR011989 Armadillo-like helical TK0835 031ac6b9e7263054ee284cbcc043c132 381 Hamap MF_01928 N5-carboxyaminoimidazole ribonucleotide synthase [purK]. 6 352 40.132 T 31-10-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 TK0835 031ac6b9e7263054ee284cbcc043c132 381 Gene3D G3DSA:3.30.1490.20 106 171 1.5E-14 T 31-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 TK0835 031ac6b9e7263054ee284cbcc043c132 381 Gene3D G3DSA:3.30.470.20 172 365 9.7E-73 T 31-10-2018 TK0835 031ac6b9e7263054ee284cbcc043c132 381 SUPERFAMILY SSF51246 297 369 2.04E-16 T 31-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 TK0835 031ac6b9e7263054ee284cbcc043c132 381 SUPERFAMILY SSF56059 101 291 1.86E-52 T 31-10-2018 TK0835 031ac6b9e7263054ee284cbcc043c132 381 Gene3D G3DSA:3.40.50.20 1 105 8.0E-37 T 31-10-2018 TK0835 031ac6b9e7263054ee284cbcc043c132 381 SUPERFAMILY SSF52440 4 97 5.32E-23 T 31-10-2018 IPR016185 Pre-ATP-grasp domain superfamily TK0835 031ac6b9e7263054ee284cbcc043c132 381 TIGRFAM TIGR01161 purK: phosphoribosylaminoimidazole carboxylase, ATPase subunit 7 351 3.0E-116 T 31-10-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 TK0835 031ac6b9e7263054ee284cbcc043c132 381 Pfam PF02222 ATP-grasp domain 110 271 5.4E-46 T 31-10-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type TK1923 fa8557cc0b0f562df322303a6dd1b89e 264 Pfam PF07853 Protein of unknown function (DUF1648) 132 176 5.0E-17 T 31-10-2018 IPR012867 Domain of unknown function DUF1648 TK1923 fa8557cc0b0f562df322303a6dd1b89e 264 Pfam PF13630 SdpI/YhfL protein family 27 88 2.9E-12 T 31-10-2018 IPR025962 SdpI/YhfL protein family TK0441 f408d57dd72dfbba6c941b92fa133f00 350 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 3 154 1.5E-15 T 31-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain TK0441 f408d57dd72dfbba6c941b92fa133f00 350 SUPERFAMILY SSF54534 3 156 3.14E-40 T 31-10-2018 TK0441 f408d57dd72dfbba6c941b92fa133f00 350 Gene3D G3DSA:3.10.50.80 3 167 2.0E-51 T 31-10-2018 TK2250 bf2039225ddeb9bb5aa892032bdebad4 311 Gene3D G3DSA:1.10.10.10 5 94 3.8E-16 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TK2250 bf2039225ddeb9bb5aa892032bdebad4 311 Pfam PF09202 Rio2, N-terminal 13 93 4.0E-23 T 31-10-2018 IPR015285 RIO2 kinase winged helix domain, N-terminal GO:0004674|GO:0005524|GO:0006468 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6791226 TK2250 bf2039225ddeb9bb5aa892032bdebad4 311 Pfam PF01163 RIO1 family 111 291 2.6E-49 T 31-10-2018 TK2250 bf2039225ddeb9bb5aa892032bdebad4 311 Gene3D G3DSA:3.30.200.20 98 196 1.7E-22 T 31-10-2018 TK2250 bf2039225ddeb9bb5aa892032bdebad4 311 SMART SM00090 68 299 3.3E-86 T 31-10-2018 IPR000687 RIO kinase GO:0004674|GO:0005524 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6791226 TK2250 bf2039225ddeb9bb5aa892032bdebad4 311 Gene3D G3DSA:1.10.510.10 203 297 8.3E-18 T 31-10-2018 TK2250 bf2039225ddeb9bb5aa892032bdebad4 311 SUPERFAMILY SSF46785 8 94 1.41E-24 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TK2250 bf2039225ddeb9bb5aa892032bdebad4 311 SUPERFAMILY SSF56112 102 273 1.16E-25 T 31-10-2018 IPR011009 Protein kinase-like domain superfamily TK1962 347b66a0a62edac141e1d90bacff7023 194 Gene3D G3DSA:1.10.10.10 83 167 2.1E-12 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TK1962 347b66a0a62edac141e1d90bacff7023 194 SUPERFAMILY SSF46785 3 79 3.66E-13 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TK1962 347b66a0a62edac141e1d90bacff7023 194 TIGRFAM TIGR00281 TIGR00281: segregation and condensation protein B 7 175 2.0E-31 T 31-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 TK1962 347b66a0a62edac141e1d90bacff7023 194 PIRSF PIRSF019345 2 194 4.0E-49 T 31-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 TK1962 347b66a0a62edac141e1d90bacff7023 194 SUPERFAMILY SSF46785 84 152 2.05E-15 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TK1962 347b66a0a62edac141e1d90bacff7023 194 Pfam PF04079 Segregation and condensation complex subunit ScpB 9 153 2.9E-36 T 31-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 TK1962 347b66a0a62edac141e1d90bacff7023 194 Gene3D G3DSA:1.10.10.10 2 82 5.7E-12 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TK1610 0b23488b20476c6794eb85c945c2118f 101 SUPERFAMILY SSF50447 23 100 7.9E-13 T 31-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily TK1610 0b23488b20476c6794eb85c945c2118f 101 Pfam PF14578 Elongation factor Tu domain 4 20 97 6.2E-21 T 31-10-2018 IPR029459 Elongation factor Tu-type domain TK1610 0b23488b20476c6794eb85c945c2118f 101 Gene3D G3DSA:2.40.30.10 13 101 2.1E-19 T 31-10-2018 TK1610 0b23488b20476c6794eb85c945c2118f 101 PIRSF PIRSF019072 1 101 1.3E-47 T 31-10-2018 IPR016744 Uncharacterised conserved protein UCP019072 TK0574 97a35b936be6f28bf3206412475928f5 670 TIGRFAM TIGR04288 CGP_CTERM: CGP-CTERM domain 650 669 5.2E-8 T 31-10-2018 IPR027552 CGP-CTERM domain TK0574 97a35b936be6f28bf3206412475928f5 670 SUPERFAMILY SSF56300 132 425 3.42E-26 T 31-10-2018 TK0574 97a35b936be6f28bf3206412475928f5 670 Pfam PF00149 Calcineurin-like phosphoesterase 133 362 1.5E-4 T 31-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 TK0574 97a35b936be6f28bf3206412475928f5 670 Gene3D G3DSA:3.60.21.10 187 450 4.4E-16 T 31-10-2018 IPR029052 Metallo-dependent phosphatase-like TK1205 5d0f165705194296dceaa7257eb7b39d 182 TIGRFAM TIGR00481 TIGR00481: Raf kinase inhibitor-like protein, YbhB/YbcL family 47 179 1.1E-43 T 31-10-2018 IPR005247 YbhB/YbcL TK1205 5d0f165705194296dceaa7257eb7b39d 182 SUPERFAMILY SSF49777 34 181 1.83E-46 T 31-10-2018 IPR036610 PEBP-like superfamily TK1205 5d0f165705194296dceaa7257eb7b39d 182 Gene3D G3DSA:3.90.280.10 32 182 2.7E-53 T 31-10-2018 IPR036610 PEBP-like superfamily TK1205 5d0f165705194296dceaa7257eb7b39d 182 Pfam PF01161 Phosphatidylethanolamine-binding protein 42 179 3.4E-36 T 31-10-2018 IPR008914 Phosphatidylethanolamine-binding protein TK2212 b86d40cd999763d7b6e25943848f5487 460 Gene3D G3DSA:3.60.21.10 1 280 3.3E-123 T 31-10-2018 IPR029052 Metallo-dependent phosphatase-like TK2212 b86d40cd999763d7b6e25943848f5487 460 Pfam PF00149 Calcineurin-like phosphoesterase 1 216 2.5E-15 T 31-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 TK2212 b86d40cd999763d7b6e25943848f5487 460 SUPERFAMILY SSF56300 1 338 1.31E-63 T 31-10-2018 TK2212 b86d40cd999763d7b6e25943848f5487 460 Hamap MF_02044 DNA double-strand break repair protein Mre11 [mre11]. 1 419 25.417 T 31-10-2018 IPR032885 DNA double-strand break repair protein Mre11, archaea-type GO:0006302 TK2212 b86d40cd999763d7b6e25943848f5487 460 Gene3D G3DSA:3.30.110.80 238 334 3.3E-123 T 31-10-2018 TK1056 71d083b9b91de35bb324631fa88008ae 158 Gene3D G3DSA:1.20.1260.10 1 142 1.8E-27 T 31-10-2018 IPR012347 Ferritin-like TK1056 71d083b9b91de35bb324631fa88008ae 158 SUPERFAMILY SSF47240 1 146 8.7E-30 T 31-10-2018 IPR009078 Ferritin-like superfamily TK1056 71d083b9b91de35bb324631fa88008ae 158 Pfam PF02915 Rubrerythrin 5 137 6.4E-16 T 31-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 TK2284 f99f374b81b307f08605a56b1b6dc569 167 Gene3D G3DSA:3.90.79.10 38 167 9.8E-43 T 31-10-2018 TK2284 f99f374b81b307f08605a56b1b6dc569 167 SUPERFAMILY SSF55811 40 165 1.35E-35 T 31-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 TK2284 f99f374b81b307f08605a56b1b6dc569 167 ProSitePatterns PS00893 Nudix box signature. 73 94 - T 31-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 TK2284 f99f374b81b307f08605a56b1b6dc569 167 Pfam PF00293 NUDIX domain 45 162 6.3E-23 T 31-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 TK2284 f99f374b81b307f08605a56b1b6dc569 167 PRINTS PR00502 NUDIX hydrolase family signature 68 82 1.7E-8 T 31-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 TK2284 f99f374b81b307f08605a56b1b6dc569 167 PRINTS PR00502 NUDIX hydrolase family signature 82 97 1.7E-8 T 31-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 TK1071 46f4832d193e0011c9e29c3b4827cd07 373 Gene3D G3DSA:3.40.720.10 1 371 1.5E-58 T 31-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 TK1071 46f4832d193e0011c9e29c3b4827cd07 373 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 7 322 8.1E-48 T 31-10-2018 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 TK1071 46f4832d193e0011c9e29c3b4827cd07 373 SUPERFAMILY SSF53649 2 359 2.76E-77 T 31-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 TK1317 2211868f53d0e38f6cda4b5ad7bbc421 139 Pfam PF01957 NfeD-like C-terminal, partner-binding 8 138 6.3E-17 T 31-10-2018 IPR002810 NfeD-like, C-terminal domain TK1317 2211868f53d0e38f6cda4b5ad7bbc421 139 SUPERFAMILY SSF141322 76 139 7.32E-21 T 31-10-2018 TK1317 2211868f53d0e38f6cda4b5ad7bbc421 139 Gene3D G3DSA:2.40.50.140 69 139 7.5E-21 T 31-10-2018 TK1149 6836d4f98b1f68114df0629659c15695 562 TIGRFAM TIGR00641 acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain 37 560 1.2E-289 T 31-10-2018 IPR006098 Methylmalonyl-CoA mutase, alpha chain, catalytic GO:0004494|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 TK1149 6836d4f98b1f68114df0629659c15695 562 SUPERFAMILY SSF51703 10 556 6.47E-231 T 31-10-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 TK1149 6836d4f98b1f68114df0629659c15695 562 Gene3D G3DSA:3.20.20.240 1 562 7.8E-270 T 31-10-2018 TK1149 6836d4f98b1f68114df0629659c15695 562 Pfam PF01642 Methylmalonyl-CoA mutase 39 554 1.8E-240 T 31-10-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 TK0259 727aca4164bee48f4541cbc9dd628066 256 Pfam PF02153 Prephenate dehydrogenase 44 174 9.3E-12 T 31-10-2018 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 TK0259 727aca4164bee48f4541cbc9dd628066 256 Gene3D G3DSA:3.40.50.720 1 155 2.4E-24 T 31-10-2018 TK0259 727aca4164bee48f4541cbc9dd628066 256 SUPERFAMILY SSF51735 1 147 2.18E-20 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily TK0211 c0724f68956a538d2160c5547c5a9c58 449 SUPERFAMILY SSF53271 238 444 2.75E-69 T 31-10-2018 IPR029057 Phosphoribosyltransferase-like TK0211 c0724f68956a538d2160c5547c5a9c58 449 Pfam PF00156 Phosphoribosyl transferase domain 277 374 3.9E-8 T 31-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 TK0211 c0724f68956a538d2160c5547c5a9c58 449 SUPERFAMILY SSF56235 5 245 5.23E-52 T 31-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TK0211 c0724f68956a538d2160c5547c5a9c58 449 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 4 442 45.013 T 31-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 TK0211 c0724f68956a538d2160c5547c5a9c58 449 Gene3D G3DSA:3.40.50.2020 263 427 5.2E-143 T 31-10-2018 TK0211 c0724f68956a538d2160c5547c5a9c58 449 PIRSF PIRSF000485 1 446 5.0E-159 T 31-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 TK0211 c0724f68956a538d2160c5547c5a9c58 449 Gene3D G3DSA:3.60.20.10 5 443 5.2E-143 T 31-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TK0211 c0724f68956a538d2160c5547c5a9c58 449 Pfam PF13537 Glutamine amidotransferase domain 72 199 3.0E-18 T 31-10-2018 IPR017932 Glutamine amidotransferase type 2 domain TK0211 c0724f68956a538d2160c5547c5a9c58 449 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 5 443 2.2E-158 T 31-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 TK1891 f78f23ffa9c4baae9583b89a1af2bba3 424 SUPERFAMILY SSF51338 1 423 1.66E-36 T 31-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 TK1891 f78f23ffa9c4baae9583b89a1af2bba3 424 Hamap MF_01281 5'-deoxyadenosine deaminase [dadD]. 2 424 48.681 T 31-10-2018 IPR023512 Deaminase MtaD/DadD GO:0019239 TK1891 f78f23ffa9c4baae9583b89a1af2bba3 424 Gene3D G3DSA:2.30.40.10 4 416 8.1E-156 T 31-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 TK1891 f78f23ffa9c4baae9583b89a1af2bba3 424 Pfam PF01979 Amidohydrolase family 51 397 1.8E-79 T 31-10-2018 IPR006680 Amidohydrolase-related GO:0016787 TK1891 f78f23ffa9c4baae9583b89a1af2bba3 424 SUPERFAMILY SSF51556 54 347 8.36E-106 T 31-10-2018 IPR032466 Metal-dependent hydrolase TK1891 f78f23ffa9c4baae9583b89a1af2bba3 424 Gene3D G3DSA:3.20.20.140 55 344 8.1E-156 T 31-10-2018 TK1905 d41babb689b01cc4c41d60c748cd3c7d 323 Gene3D G3DSA:3.40.1350.10 205 304 9.4E-8 T 31-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 TK0229 d438d0cce9b24368b4395f66c4afa6cd 68 Gene3D G3DSA:3.40.630.30 3 65 1.3E-7 T 31-10-2018 TK0229 d438d0cce9b24368b4395f66c4afa6cd 68 SUPERFAMILY SSF55729 13 62 2.71E-5 T 31-10-2018 IPR016181 Acyl-CoA N-acyltransferase TK1393 77c3b5c8926d29bb7cbaf394b98a00e2 496 Gene3D G3DSA:3.30.9.10 90 321 1.3E-115 T 31-10-2018 TK1393 77c3b5c8926d29bb7cbaf394b98a00e2 496 Pfam PF01266 FAD dependent oxidoreductase 4 357 4.1E-68 T 31-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 TK1393 77c3b5c8926d29bb7cbaf394b98a00e2 496 Gene3D G3DSA:1.10.10.1100 393 473 3.9E-18 T 31-10-2018 TK1393 77c3b5c8926d29bb7cbaf394b98a00e2 496 Pfam PF04324 BFD-like [2Fe-2S] binding domain 406 464 6.0E-16 T 31-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain TK1393 77c3b5c8926d29bb7cbaf394b98a00e2 496 Gene3D G3DSA:3.50.50.60 5 354 1.3E-115 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TK1393 77c3b5c8926d29bb7cbaf394b98a00e2 496 SUPERFAMILY SSF54373 223 318 5.76E-8 T 31-10-2018 TK1393 77c3b5c8926d29bb7cbaf394b98a00e2 496 SUPERFAMILY SSF51905 3 410 5.18E-57 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TK0128 088151d7a6e4e9b18b55d437ed35f8b8 143 SMART SM00670 2 133 2.3E-6 T 31-10-2018 IPR002716 PIN domain TK0128 088151d7a6e4e9b18b55d437ed35f8b8 143 Pfam PF01850 PIN domain 4 136 1.5E-22 T 31-10-2018 IPR002716 PIN domain TK0128 088151d7a6e4e9b18b55d437ed35f8b8 143 Gene3D G3DSA:3.40.50.1010 3 141 5.1E-12 T 31-10-2018 TK0128 088151d7a6e4e9b18b55d437ed35f8b8 143 SUPERFAMILY SSF88723 1 134 3.36E-20 T 31-10-2018 IPR029060 PIN-like domain superfamily TK1615 504eb5dc677cf10586dc29ec0ed2cc06 343 TIGRFAM TIGR03399 RNA_3prim_cycl: RNA 3'-phosphate cyclase 4 324 2.2E-130 T 31-10-2018 IPR017770 RNA 3'-terminal phosphate cyclase type 1 GO:0003963|GO:0006396 TK1615 504eb5dc677cf10586dc29ec0ed2cc06 343 Pfam PF05189 RNA 3'-terminal phosphate cyclase (RTC), insert domain 183 275 6.9E-23 T 31-10-2018 IPR013791 RNA 3'-terminal phosphate cyclase, insert domain TK1615 504eb5dc677cf10586dc29ec0ed2cc06 343 PIRSF PIRSF005378 1 340 1.6E-114 T 31-10-2018 IPR000228 RNA 3'-terminal phosphate cyclase GO:0006396 TK1615 504eb5dc677cf10586dc29ec0ed2cc06 343 Hamap MF_00200 RNA 3'-terminal phosphate cyclase [rtcA]. 3 338 40.363 T 31-10-2018 IPR017770 RNA 3'-terminal phosphate cyclase type 1 GO:0003963|GO:0006396 TK1615 504eb5dc677cf10586dc29ec0ed2cc06 343 Gene3D G3DSA:3.30.360.20 179 276 5.2E-129 T 31-10-2018 IPR036553 RNA 3'-terminal phosphate cyclase, insert domain superfamily TK1615 504eb5dc677cf10586dc29ec0ed2cc06 343 ProSitePatterns PS01287 RNA 3'-terminal phosphate cyclase signature. 154 164 - T 31-10-2018 IPR020719 RNA 3'-terminal phosphate cyclase-like, conserved site TK1615 504eb5dc677cf10586dc29ec0ed2cc06 343 Pfam PF01137 RNA 3'-terminal phosphate cyclase 10 326 1.1E-79 T 31-10-2018 IPR023797 RNA 3'-terminal phosphate cyclase domain TK1615 504eb5dc677cf10586dc29ec0ed2cc06 343 SUPERFAMILY SSF52913 185 278 1.24E-24 T 31-10-2018 IPR036553 RNA 3'-terminal phosphate cyclase, insert domain superfamily TK1615 504eb5dc677cf10586dc29ec0ed2cc06 343 SUPERFAMILY SSF55205 4 217 4.38E-69 T 31-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 TK1615 504eb5dc677cf10586dc29ec0ed2cc06 343 Gene3D G3DSA:3.65.10.20 5 320 5.2E-129 T 31-10-2018 IPR037136 RNA 3'-terminal phosphate cyclase domain superfamily TK1278 2341491bf0a2d6c89150450a2ebef6f6 112 SUPERFAMILY SSF46950 8 111 1.7E-27 T 31-10-2018 IPR036883 PDCD5-like superfamily GO:0003677 TK1278 2341491bf0a2d6c89150450a2ebef6f6 112 Pfam PF01984 Double-stranded DNA-binding domain 8 111 9.8E-27 T 31-10-2018 IPR002836 PDCD5-like GO:0003677 TK1278 2341491bf0a2d6c89150450a2ebef6f6 112 Gene3D G3DSA:1.10.8.140 31 112 2.1E-26 T 31-10-2018 IPR036883 PDCD5-like superfamily GO:0003677 TK1278 2341491bf0a2d6c89150450a2ebef6f6 112 Hamap MF_00026 DNA-binding protein . 3 112 16.059 T 31-10-2018 IPR022889 DNA-binding protein, archaeal TK1278 2341491bf0a2d6c89150450a2ebef6f6 112 PIRSF PIRSF015730 1 112 1.8E-34 T 31-10-2018 IPR002836 PDCD5-like GO:0003677 TK1908 2e5b7b4f19616d392df433cec0bfc696 249 SUPERFAMILY SSF55681 1 246 2.73E-70 T 31-10-2018 TK1908 2e5b7b4f19616d392df433cec0bfc696 249 Gene3D G3DSA:3.30.930.10 8 249 1.5E-64 T 31-10-2018 TK1908 2e5b7b4f19616d392df433cec0bfc696 249 Pfam PF03099 Biotin/lipoate A/B protein ligase family 54 157 5.6E-14 T 31-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 TK2080 d3cd247a17f41823911d3f4e077ab5e3 167 Pfam PF01899 Na+/H+ ion antiporter subunit 7 164 2.0E-44 T 31-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 TK2080 d3cd247a17f41823911d3f4e077ab5e3 167 PIRSF PIRSF019239 1 165 3.4E-41 T 31-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 TK2288 69b86e456a512e9f3c8e73405e5263e0 164 TIGRFAM TIGR00040 yfcE: phosphodiesterase, MJ0936 family 2 156 7.5E-35 T 31-10-2018 IPR000979 Phosphodiesterase MJ0936/Vps29 Reactome: R-HSA-3238698 TK2288 69b86e456a512e9f3c8e73405e5263e0 164 SUPERFAMILY SSF56300 2 163 8.35E-37 T 31-10-2018 TK2288 69b86e456a512e9f3c8e73405e5263e0 164 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 2 151 1.8E-29 T 31-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 TK2288 69b86e456a512e9f3c8e73405e5263e0 164 Gene3D G3DSA:3.60.21.10 1 163 6.2E-40 T 31-10-2018 IPR029052 Metallo-dependent phosphatase-like TK1415 75820a2e07141f1409078218dc654d42 106 Gene3D G3DSA:1.10.10.1410 1 58 3.4E-31 T 31-10-2018 IPR038716 Ribosomal protein P1/P2, N-terminal domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1415 75820a2e07141f1409078218dc654d42 106 Hamap MF_01478 50S ribosomal protein L12 [rpl12]. 1 103 14.566 T 31-10-2018 IPR027534 Ribosomal protein L12 family GO:0003735|GO:0005622|GO:0005840|GO:0006414 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1415 75820a2e07141f1409078218dc654d42 106 TIGRFAM TIGR03685 ribo_P1_arch: 50S ribosomal protein P1 1 106 9.4E-42 T 31-10-2018 IPR022295 Ribosomal protein L12, archaea GO:0003735|GO:0005840|GO:0006414 TK1415 75820a2e07141f1409078218dc654d42 106 Pfam PF00428 60s Acidic ribosomal protein 16 105 6.2E-20 T 31-10-2018 TK0649 90fd68b75c818ed338835226ca75fabe 241 SUPERFAMILY SSF50249 134 223 1.4E-16 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold TK0649 90fd68b75c818ed338835226ca75fabe 241 Gene3D G3DSA:2.40.50.140 125 241 1.0E-35 T 31-10-2018 TK0649 90fd68b75c818ed338835226ca75fabe 241 Gene3D G3DSA:1.20.1440.150 1 124 1.9E-60 T 31-10-2018 TK0649 90fd68b75c818ed338835226ca75fabe 241 Pfam PF01588 Putative tRNA binding domain 138 224 1.3E-18 T 31-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 TK0786 ef46fc60a5adf68b8201990be732b1f7 206 Gene3D G3DSA:1.20.1540.10 3 199 7.9E-37 T 31-10-2018 IPR035952 Rhomboid-like superfamily TK0786 ef46fc60a5adf68b8201990be732b1f7 206 SUPERFAMILY SSF144091 9 195 2.09E-39 T 31-10-2018 TK0786 ef46fc60a5adf68b8201990be732b1f7 206 Pfam PF01694 Rhomboid family 56 190 6.6E-30 T 31-10-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 TK1875 7f70adf1ae346384380d6c4f22c0b251 58 SUPERFAMILY SSF141694 1 49 1.1E-12 T 31-10-2018 TK1875 7f70adf1ae346384380d6c4f22c0b251 58 Gene3D G3DSA:4.10.1150.10 1 58 2.4E-7 T 31-10-2018 IPR024069 AF2212-like domain superfamily TK1875 7f70adf1ae346384380d6c4f22c0b251 58 Pfam PF01954 Protein of unknown function DUF104 2 55 1.2E-16 T 31-10-2018 IPR008203 Uncharacterised protein family UPF0165 TK1619 ea7365ae0e41178db0e8a933a194a59d 164 Pfam PF05916 GINS complex protein 28 147 1.9E-9 T 31-10-2018 IPR021151 GINS subunit, domain A Reactome: R-HSA-176974 TK1619 ea7365ae0e41178db0e8a933a194a59d 164 Gene3D G3DSA:1.20.58.2050 1 164 2.3E-94 T 31-10-2018 IPR038437 GINS complex, subunit Psf3 superfamily Reactome: R-HSA-176974 TK2281 5c0581795c4d26c891c45c32cefc6211 253 SUPERFAMILY SSF52540 2 223 5.33E-63 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK2281 5c0581795c4d26c891c45c32cefc6211 253 SMART SM00382 26 209 7.4E-11 T 31-10-2018 IPR003593 AAA+ ATPase domain TK2281 5c0581795c4d26c891c45c32cefc6211 253 Gene3D G3DSA:3.40.50.300 1 242 9.8E-70 T 31-10-2018 TK2281 5c0581795c4d26c891c45c32cefc6211 253 Pfam PF00005 ABC transporter 18 161 1.8E-27 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TK0745 69376569d25f7d7cec666de204d66137 256 Pfam PF02361 Cobalt transport protein 11 210 5.1E-28 T 31-10-2018 IPR003339 ABC/ECF transporter, transmembrane component TK0173 b77ee14f16db9eb9e75400e6fd2ec564 100 SUPERFAMILY SSF89957 1 96 2.88E-31 T 31-10-2018 IPR029756 MTH1187/YkoF-like TK0173 b77ee14f16db9eb9e75400e6fd2ec564 100 Gene3D G3DSA:3.30.70.930 1 97 1.8E-35 T 31-10-2018 IPR029756 MTH1187/YkoF-like TK0173 b77ee14f16db9eb9e75400e6fd2ec564 100 TIGRFAM TIGR00106 TIGR00106: uncharacterized protein, MTH1187 family 2 97 1.9E-30 T 31-10-2018 IPR002767 Thiamine-binding protein TK0173 b77ee14f16db9eb9e75400e6fd2ec564 100 Pfam PF01910 Thiamine-binding protein 4 93 3.5E-33 T 31-10-2018 IPR002767 Thiamine-binding protein TK0263 a6383bd8c56b13260b2065f6ae3179b7 399 ProSitePatterns PS00885 EPSP synthase signature 2. 312 330 - T 31-10-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 TK0263 a6383bd8c56b13260b2065f6ae3179b7 399 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 4 394 3.0E-102 T 31-10-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 TK0263 a6383bd8c56b13260b2065f6ae3179b7 399 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 11 398 2.9E-128 T 31-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 TK0263 a6383bd8c56b13260b2065f6ae3179b7 399 Gene3D G3DSA:3.65.10.10 11 390 7.4E-120 T 31-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 TK0263 a6383bd8c56b13260b2065f6ae3179b7 399 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 7 399 31.889 T 31-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 TK0263 a6383bd8c56b13260b2065f6ae3179b7 399 Gene3D G3DSA:3.65.10.10 19 220 7.4E-120 T 31-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 TK0263 a6383bd8c56b13260b2065f6ae3179b7 399 PIRSF PIRSF000505 2 399 2.6E-130 T 31-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 TK0263 a6383bd8c56b13260b2065f6ae3179b7 399 SUPERFAMILY SSF55205 2 397 1.16E-109 T 31-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 TK0094 2a0610674819e74e6200029244fccbf5 125 PIRSF PIRSF019240 4 119 5.0E-20 T 31-10-2018 IPR016752 Uncharacterised conserved protein UCP019240, SpoVT/AbrB-related TK0094 2a0610674819e74e6200029244fccbf5 125 SMART SM00966 73 116 1.2E-5 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 TK0094 2a0610674819e74e6200029244fccbf5 125 SMART SM00966 20 65 12.0 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 TK0094 2a0610674819e74e6200029244fccbf5 125 SUPERFAMILY SSF89447 19 50 5.89E-6 T 31-10-2018 IPR037914 SpoVT-AbrB domain superfamily TK0094 2a0610674819e74e6200029244fccbf5 125 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 74 105 1.3E-6 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 TK0094 2a0610674819e74e6200029244fccbf5 125 SUPERFAMILY SSF89447 69 105 5.58E-8 T 31-10-2018 IPR037914 SpoVT-AbrB domain superfamily TK0094 2a0610674819e74e6200029244fccbf5 125 Gene3D G3DSA:2.10.260.10 12 111 2.0E-24 T 31-10-2018 TK1562 397bbda441820c1af11e0eabb76f197a 436 PIRSF PIRSF001549 1 434 7.6E-139 T 31-10-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 TK1562 397bbda441820c1af11e0eabb76f197a 436 Pfam PF13393 Histidyl-tRNA synthetase 9 323 3.3E-66 T 31-10-2018 TK1562 397bbda441820c1af11e0eabb76f197a 436 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 6 422 2.8E-127 T 31-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 TK1562 397bbda441820c1af11e0eabb76f197a 436 Pfam PF03129 Anticodon binding domain 341 432 7.7E-19 T 31-10-2018 IPR004154 Anticodon-binding TK1562 397bbda441820c1af11e0eabb76f197a 436 SUPERFAMILY SSF55681 7 328 1.99E-87 T 31-10-2018 TK1562 397bbda441820c1af11e0eabb76f197a 436 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 2 432 31.192 T 31-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 TK1562 397bbda441820c1af11e0eabb76f197a 436 Hamap MF_00125 ATP phosphoribosyltransferase regulatory subunit [hisZ]. 16 383 25.785 T 31-10-2018 IPR004517 ATP phosphoribosyltransferase regulatory subunit GO:0000105|GO:0005737 TK1562 397bbda441820c1af11e0eabb76f197a 436 SUPERFAMILY SSF52954 330 434 6.64E-22 T 31-10-2018 TK1562 397bbda441820c1af11e0eabb76f197a 436 Gene3D G3DSA:3.30.930.10 1 328 1.1E-110 T 31-10-2018 TK1562 397bbda441820c1af11e0eabb76f197a 436 Gene3D G3DSA:3.40.50.800 338 433 1.7E-24 T 31-10-2018 IPR036621 Anticodon-binding domain superfamily TK1562 397bbda441820c1af11e0eabb76f197a 436 TIGRFAM TIGR00443 hisZ_biosyn_reg: ATP phosphoribosyltransferase, regulatory subunit 11 326 6.3E-87 T 31-10-2018 IPR004517 ATP phosphoribosyltransferase regulatory subunit GO:0000105|GO:0005737 TK0929 14c1517d9cf16181523626d102c7c0cf 421 Gene3D G3DSA:3.40.1670.10 296 408 6.0E-38 T 31-10-2018 TK0929 14c1517d9cf16181523626d102c7c0cf 421 SUPERFAMILY SSF50475 5 279 6.28E-66 T 31-10-2018 TK0929 14c1517d9cf16181523626d102c7c0cf 421 SUPERFAMILY SSF143968 282 419 1.07E-42 T 31-10-2018 TK0929 14c1517d9cf16181523626d102c7c0cf 421 Pfam PF01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 6 385 3.1E-102 T 31-10-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 TK0929 14c1517d9cf16181523626d102c7c0cf 421 TIGRFAM TIGR00148 TIGR00148: decarboxylase, UbiD family 3 409 1.0E-116 T 31-10-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 TK1293 7a00e130d7ff45ae9657cb04872201f7 825 Gene3D G3DSA:3.40.50.12610 382 492 1.6E-7 T 31-10-2018 TK1293 7a00e130d7ff45ae9657cb04872201f7 825 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 72 222 3.6E-12 T 31-10-2018 IPR038731 Glycosyltransferase RgtA/B/C/D-like TK1293 7a00e130d7ff45ae9657cb04872201f7 825 Gene3D G3DSA:1.50.10.20 543 802 9.2E-9 T 31-10-2018 TK1293 7a00e130d7ff45ae9657cb04872201f7 825 SUPERFAMILY SSF81853 650 814 9.42E-17 T 31-10-2018 TK2069 a68ed4a798481acd48d933d7346e1a54 428 SUPERFAMILY SSF56762 8 424 1.26E-98 T 31-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TK2069 a68ed4a798481acd48d933d7346e1a54 428 Pfam PF00374 Nickel-dependent hydrogenase 243 424 7.3E-12 T 31-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 TK2069 a68ed4a798481acd48d933d7346e1a54 428 Pfam PF00374 Nickel-dependent hydrogenase 43 121 1.3E-11 T 31-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 TK2069 a68ed4a798481acd48d933d7346e1a54 428 ProSitePatterns PS00508 Nickel-dependent hydrogenases large subunit signature 2. 415 424 - T 31-10-2018 IPR018194 Nickel-dependent hydrogenase, large subunit, nickel binding site GO:0008901|GO:0016151|GO:0055114 TK2069 a68ed4a798481acd48d933d7346e1a54 428 Gene3D G3DSA:1.10.645.10 6 424 7.1E-107 T 31-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TK1618 29731248c23416236d872564d884a167 170 ProSitePatterns PS01269 Uncharacterized protein family UPF0025 signature. 108 132 - T 31-10-2018 IPR020935 Phosphodiesterase YfcE, conserved site TK1618 29731248c23416236d872564d884a167 170 TIGRFAM TIGR00040 yfcE: phosphodiesterase, MJ0936 family 1 155 1.9E-39 T 31-10-2018 IPR000979 Phosphodiesterase MJ0936/Vps29 Reactome: R-HSA-3238698 TK1618 29731248c23416236d872564d884a167 170 Gene3D G3DSA:3.60.21.10 1 159 2.0E-52 T 31-10-2018 IPR029052 Metallo-dependent phosphatase-like TK1618 29731248c23416236d872564d884a167 170 SUPERFAMILY SSF56300 1 158 2.17E-39 T 31-10-2018 TK1618 29731248c23416236d872564d884a167 170 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 1 151 1.6E-33 T 31-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 TK2246 f3581b3404f527678a8b4cafb49ca81e 306 Pfam PF01112 Asparaginase 3 298 4.0E-94 T 31-10-2018 IPR000246 Peptidase T2, asparaginase 2 GO:0016787 TK2246 f3581b3404f527678a8b4cafb49ca81e 306 Gene3D G3DSA:3.60.20.30 176 303 7.8E-34 T 31-10-2018 TK2246 f3581b3404f527678a8b4cafb49ca81e 306 SUPERFAMILY SSF56235 18 298 5.4E-87 T 31-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TK0190 f79e79314b1861e283eb22f848a7ab27 188 Pfam PF00117 Glutamine amidotransferase class-I 4 181 5.5E-46 T 31-10-2018 IPR017926 Glutamine amidotransferase TK0190 f79e79314b1861e283eb22f848a7ab27 188 Hamap MF_01510 GMP synthase [glutamine-hydrolyzing] subunit A [guaAA]. 1 187 45.602 T 31-10-2018 IPR023686 GMP synthase (glutamine-hydrolyzing) subunit A GO:0003922 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 TK0190 f79e79314b1861e283eb22f848a7ab27 188 PRINTS PR00097 Anthranilate synthase component II signature 46 55 1.7E-11 T 31-10-2018 TK0190 f79e79314b1861e283eb22f848a7ab27 188 PRINTS PR00097 Anthranilate synthase component II signature 161 174 1.7E-11 T 31-10-2018 TK0190 f79e79314b1861e283eb22f848a7ab27 188 PRINTS PR00097 Anthranilate synthase component II signature 2 16 1.7E-11 T 31-10-2018 TK0190 f79e79314b1861e283eb22f848a7ab27 188 PRINTS PR00097 Anthranilate synthase component II signature 73 84 1.7E-11 T 31-10-2018 TK0190 f79e79314b1861e283eb22f848a7ab27 188 PRINTS PR00096 Glutamine amidotransferase superfamily signature 46 55 6.8E-10 T 31-10-2018 TK0190 f79e79314b1861e283eb22f848a7ab27 188 PRINTS PR00096 Glutamine amidotransferase superfamily signature 161 174 6.8E-10 T 31-10-2018 TK0190 f79e79314b1861e283eb22f848a7ab27 188 PRINTS PR00096 Glutamine amidotransferase superfamily signature 73 84 6.8E-10 T 31-10-2018 TK0190 f79e79314b1861e283eb22f848a7ab27 188 Gene3D G3DSA:3.40.50.880 1 187 1.1E-61 T 31-10-2018 IPR029062 Class I glutamine amidotransferase-like TK0190 f79e79314b1861e283eb22f848a7ab27 188 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 73 89 1.1E-5 T 31-10-2018 TK0190 f79e79314b1861e283eb22f848a7ab27 188 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 43 57 1.1E-5 T 31-10-2018 TK0190 f79e79314b1861e283eb22f848a7ab27 188 SUPERFAMILY SSF52317 1 186 6.66E-56 T 31-10-2018 IPR029062 Class I glutamine amidotransferase-like TK0190 f79e79314b1861e283eb22f848a7ab27 188 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 2 186 9.0E-82 T 31-10-2018 IPR004739 GMP synthase, glutamine amidotransferase GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 TK1281 170f31a8ba9d7c0fe9918a00da02828b 340 SUPERFAMILY SSF88723 7 236 9.81E-68 T 31-10-2018 IPR029060 PIN-like domain superfamily TK1281 170f31a8ba9d7c0fe9918a00da02828b 340 SUPERFAMILY SSF47807 221 339 1.94E-33 T 31-10-2018 IPR036279 5'-3' exonuclease, C-terminal domain superfamily TK1281 170f31a8ba9d7c0fe9918a00da02828b 340 Gene3D G3DSA:3.40.50.1010 1 220 2.0E-89 T 31-10-2018 TK1281 170f31a8ba9d7c0fe9918a00da02828b 340 TIGRFAM TIGR03674 fen_arch: flap structure-specific endonuclease 1 338 8.1E-158 T 31-10-2018 IPR019973 Flap structure-specific endonuclease, archaea GO:0016788 TK1281 170f31a8ba9d7c0fe9918a00da02828b 340 Gene3D G3DSA:1.10.150.20 221 281 7.1E-21 T 31-10-2018 TK1281 170f31a8ba9d7c0fe9918a00da02828b 340 Hamap MF_00614 Flap endonuclease 1 [fen]. 1 339 148.995 T 31-10-2018 IPR023426 Flap endonuclease 1 GO:0016788 Reactome: R-HSA-110362|Reactome: R-HSA-162594|Reactome: R-HSA-174437|Reactome: R-HSA-5651801|Reactome: R-HSA-5685939|Reactome: R-HSA-69166 TK1281 170f31a8ba9d7c0fe9918a00da02828b 340 Pfam PF00752 XPG N-terminal domain 12 101 7.2E-23 T 31-10-2018 IPR006085 XPG N-terminal GO:0004518|GO:0006281 TK1281 170f31a8ba9d7c0fe9918a00da02828b 340 SMART SM00485 1 101 9.1E-52 T 31-10-2018 IPR006085 XPG N-terminal GO:0004518|GO:0006281 TK1281 170f31a8ba9d7c0fe9918a00da02828b 340 SMART SM00279 223 257 1.6E-11 T 31-10-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 TK1281 170f31a8ba9d7c0fe9918a00da02828b 340 ProSitePatterns PS00841 XPG protein signature 1. 73 87 - T 31-10-2018 IPR019974 XPG conserved site GO:0016788 TK1281 170f31a8ba9d7c0fe9918a00da02828b 340 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 139 156 5.0E-33 T 31-10-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 TK1281 170f31a8ba9d7c0fe9918a00da02828b 340 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 226 241 5.0E-33 T 31-10-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 TK1281 170f31a8ba9d7c0fe9918a00da02828b 340 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 75 94 5.0E-33 T 31-10-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 TK1281 170f31a8ba9d7c0fe9918a00da02828b 340 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 160 180 5.0E-33 T 31-10-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 TK1281 170f31a8ba9d7c0fe9918a00da02828b 340 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 21 35 5.0E-33 T 31-10-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 TK1281 170f31a8ba9d7c0fe9918a00da02828b 340 Pfam PF00867 XPG I-region 141 236 1.8E-28 T 31-10-2018 IPR006086 XPG-I domain GO:0004518 TK1281 170f31a8ba9d7c0fe9918a00da02828b 340 SMART SM00484 140 221 8.4E-38 T 31-10-2018 IPR006086 XPG-I domain GO:0004518 TK1314 a74117ed60a454897b7a9ce39afa4f21 434 Pfam PF13173 AAA domain 35 166 3.8E-34 T 31-10-2018 TK1314 a74117ed60a454897b7a9ce39afa4f21 434 Pfam PF13635 Domain of unknown function (DUF4143) 250 374 6.3E-11 T 31-10-2018 IPR025420 Domain of unknown function DUF4143 TK1314 a74117ed60a454897b7a9ce39afa4f21 434 SUPERFAMILY SSF52540 36 200 1.2E-17 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK2005 f49430354df8ac0912958b74d601e115 172 SUPERFAMILY SSF88723 14 141 5.49E-5 T 31-10-2018 IPR029060 PIN-like domain superfamily TK2005 f49430354df8ac0912958b74d601e115 172 SMART SM00670 13 137 5.9E-6 T 31-10-2018 IPR002716 PIN domain TK2005 f49430354df8ac0912958b74d601e115 172 Pfam PF13470 PIN domain 14 133 7.0E-18 T 31-10-2018 IPR002716 PIN domain TK2005 f49430354df8ac0912958b74d601e115 172 TIGRFAM TIGR00305 TIGR00305: putative toxin-antitoxin system toxin component, PIN family 14 137 7.2E-24 T 31-10-2018 IPR002850 PIN family, putative toxin-antitoxin system toxin component TK1084 104a431442869515c556638d22c4bc06 82 SUPERFAMILY SSF55287 7 80 3.27E-29 T 31-10-2018 IPR035913 RPB5-like RNA polymerase subunit superfamily Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 TK1084 104a431442869515c556638d22c4bc06 82 Pfam PF01191 RNA polymerase Rpb5, C-terminal domain 7 79 2.9E-33 T 31-10-2018 IPR000783 RNA polymerase, subunit H/Rpb5 C-terminal GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 TK1084 104a431442869515c556638d22c4bc06 82 ProSitePatterns PS01110 RNA polymerases H / 23 Kd subunits signature. 12 25 - T 31-10-2018 IPR020608 RNA polymerase, subunit H/Rpb5, conserved site Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 TK1084 104a431442869515c556638d22c4bc06 82 Hamap MF_00025 DNA-directed RNA polymerase subunit H [rpoH]. 7 80 23.965 T 31-10-2018 IPR020609 Archaeal RpoH /eukaryotic RPB5 RNA polymerase subunit GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 TK1084 104a431442869515c556638d22c4bc06 82 Gene3D G3DSA:3.90.940.20 1 82 4.7E-38 T 31-10-2018 IPR035913 RPB5-like RNA polymerase subunit superfamily Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 TK1084 104a431442869515c556638d22c4bc06 82 ProDom PD005155 RNA POLYMERASE DNA-DIRECTED SUBUNIT NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION II H POLYPEPTIDE 14 79 1.0E-22 T 31-10-2018 IPR000783 RNA polymerase, subunit H/Rpb5 C-terminal GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 TK1320 022b09f1ee18b2e723dd859b545eda5a 90 Hamap MF_00410 50S ribosomal protein L31e [rpl31e]. 4 90 21.369 T 31-10-2018 IPR000054 Ribosomal protein L31e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1320 022b09f1ee18b2e723dd859b545eda5a 90 Pfam PF01198 Ribosomal protein L31e 13 79 2.0E-9 T 31-10-2018 IPR000054 Ribosomal protein L31e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1320 022b09f1ee18b2e723dd859b545eda5a 90 ProDom PD006030 RIBOSOMAL 60S L31 RIBONUCLEOPROTEIN L31E 50S L31 SUBUNIT STRAIN PHOSPHORYLATION 13 58 9.0E-19 T 31-10-2018 IPR000054 Ribosomal protein L31e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1320 022b09f1ee18b2e723dd859b545eda5a 90 SUPERFAMILY SSF54575 7 84 2.75E-22 T 31-10-2018 IPR023621 Ribosomal protein L31e domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1320 022b09f1ee18b2e723dd859b545eda5a 90 SMART SM01380 8 82 3.2E-19 T 31-10-2018 IPR000054 Ribosomal protein L31e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1320 022b09f1ee18b2e723dd859b545eda5a 90 ProSitePatterns PS01144 Ribosomal protein L31e signature. 48 62 - T 31-10-2018 IPR020052 Ribosomal protein L31e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1320 022b09f1ee18b2e723dd859b545eda5a 90 Gene3D G3DSA:3.10.440.10 2 90 2.5E-25 T 31-10-2018 IPR023621 Ribosomal protein L31e domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1256 3714b1389a7453b3f71cd9ff58d49907 141 Pfam PF01850 PIN domain 9 134 4.5E-18 T 31-10-2018 IPR002716 PIN domain TK1256 3714b1389a7453b3f71cd9ff58d49907 141 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 9 141 11.133 T 31-10-2018 IPR022907 VapC family GO:0004540 TK1256 3714b1389a7453b3f71cd9ff58d49907 141 Gene3D G3DSA:3.40.50.1010 8 140 1.7E-30 T 31-10-2018 TK1256 3714b1389a7453b3f71cd9ff58d49907 141 SUPERFAMILY SSF88723 9 139 9.81E-29 T 31-10-2018 IPR029060 PIN-like domain superfamily TK1576 cccf67301f665b1725d3275f18ba2d29 187 Pfam PF03729 Short repeat of unknown function (DUF308) 16 85 2.5E-12 T 31-10-2018 IPR005325 Protein of unknown function DUF308, membrane TK1576 cccf67301f665b1725d3275f18ba2d29 187 Pfam PF03729 Short repeat of unknown function (DUF308) 72 141 2.3E-9 T 31-10-2018 IPR005325 Protein of unknown function DUF308, membrane TK1758 3ae37ee99935dc501b42e9db13798c2e 314 Gene3D G3DSA:1.10.3720.10 96 312 1.9E-18 T 31-10-2018 IPR035906 MetI-like superfamily TK1758 3ae37ee99935dc501b42e9db13798c2e 314 SUPERFAMILY SSF161098 102 290 1.7E-19 T 31-10-2018 IPR035906 MetI-like superfamily TK1758 3ae37ee99935dc501b42e9db13798c2e 314 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 124 311 7.0E-23 T 31-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TK1546 a5c32deeb8c0672b7faf4dca94b640dd 182 PIRSF PIRSF005590 1 180 4.8E-69 T 31-10-2018 IPR001197 Ribosomal protein L10e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1546 a5c32deeb8c0672b7faf4dca94b640dd 182 Hamap MF_00448 50S ribosomal protein L10e [rpl10e]. 1 174 36.744 T 31-10-2018 IPR022981 Ribosomal protein L10e, archaea TK1546 a5c32deeb8c0672b7faf4dca94b640dd 182 Gene3D G3DSA:3.90.1170.10 1 180 1.8E-64 T 31-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 TK1546 a5c32deeb8c0672b7faf4dca94b640dd 182 SUPERFAMILY SSF54686 4 168 1.83E-56 T 31-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 TK1546 a5c32deeb8c0672b7faf4dca94b640dd 182 ProSitePatterns PS01257 Ribosomal protein L10e signature. 105 126 - T 31-10-2018 IPR018255 Ribosomal protein L10e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1546 a5c32deeb8c0672b7faf4dca94b640dd 182 Pfam PF00252 Ribosomal protein L16p/L10e 14 159 1.7E-32 T 31-10-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 TK0910 09ac9be5375e221d357d9502ba308f5f 149 SMART SM00670 1 142 2.2E-12 T 31-10-2018 IPR002716 PIN domain TK0910 09ac9be5375e221d357d9502ba308f5f 149 Pfam PF01850 PIN domain 1 143 2.3E-20 T 31-10-2018 IPR002716 PIN domain TK0910 09ac9be5375e221d357d9502ba308f5f 149 Gene3D G3DSA:3.40.50.1010 1 148 1.6E-10 T 31-10-2018 TK0910 09ac9be5375e221d357d9502ba308f5f 149 SUPERFAMILY SSF88723 1 148 1.85E-19 T 31-10-2018 IPR029060 PIN-like domain superfamily TK2277 ba9eaeb8ac4e12a28e4fb2dca67ae44e 200 Gene3D G3DSA:3.30.1360.30 81 191 1.6E-45 T 31-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 TK2277 ba9eaeb8ac4e12a28e4fb2dca67ae44e 200 SUPERFAMILY SSF55261 83 198 5.23E-40 T 31-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 TK2277 ba9eaeb8ac4e12a28e4fb2dca67ae44e 200 Gene3D G3DSA:1.10.10.10 1 80 2.5E-24 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TK2277 ba9eaeb8ac4e12a28e4fb2dca67ae44e 200 SUPERFAMILY SSF46785 17 76 3.44E-10 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TK2277 ba9eaeb8ac4e12a28e4fb2dca67ae44e 200 Pfam PF14544 Domain of unknown function (DUF4443) 80 191 4.1E-69 T 31-10-2018 IPR029349 Domain of unknown function DUF4443 TK0976 a41cd4a1982daddd9667f4965d216035 76 SUPERFAMILY SSF50182 5 73 1.46E-17 T 31-10-2018 IPR010920 LSM domain superfamily TK0976 a41cd4a1982daddd9667f4965d216035 76 SMART SM00651 7 72 4.4E-20 T 31-10-2018 IPR001163 LSM domain, eukaryotic/archaea-type TK0976 a41cd4a1982daddd9667f4965d216035 76 Gene3D G3DSA:2.30.30.100 1 74 1.5E-23 T 31-10-2018 TK0976 a41cd4a1982daddd9667f4965d216035 76 Hamap MF_00257 Putative snRNP Sm-like protein. 1 72 25.395 T 31-10-2018 IPR022901 snRNP Sm-like, putative, archaea TK0976 a41cd4a1982daddd9667f4965d216035 76 Pfam PF01423 LSM domain 8 72 5.3E-19 T 31-10-2018 IPR001163 LSM domain, eukaryotic/archaea-type TK1216 3c3754c29144cb041af0908d7f5bb6b3 177 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 89 130 3.0E-18 T 31-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TK1216 3c3754c29144cb041af0908d7f5bb6b3 177 SUPERFAMILY SSF143243 27 163 5.62E-36 T 31-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TK1216 3c3754c29144cb041af0908d7f5bb6b3 177 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 39 155 1.2E-31 T 31-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TK1216 3c3754c29144cb041af0908d7f5bb6b3 177 Gene3D G3DSA:3.30.460.80 3 133 3.8E-27 T 31-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TK0212 020a5b3be1f424f124f1b3ab61e42e80 162 Pfam PF11848 Domain of unknown function (DUF3368) 113 157 2.1E-10 T 31-10-2018 IPR021799 Protein of unknown function DUF3368 TK1055 2c932558df99e8879b7e3ba1a0e9d2ac 154 SUPERFAMILY SSF52833 6 149 5.54E-47 T 31-10-2018 IPR036249 Thioredoxin-like superfamily TK1055 2c932558df99e8879b7e3ba1a0e9d2ac 154 Gene3D G3DSA:3.40.30.10 2 149 3.5E-46 T 31-10-2018 TK1055 2c932558df99e8879b7e3ba1a0e9d2ac 154 Pfam PF00578 AhpC/TSA family 6 128 2.9E-34 T 31-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 TK1055 2c932558df99e8879b7e3ba1a0e9d2ac 154 PIRSF PIRSF000239 2 152 2.2E-25 T 31-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 TK0442 71a1eb6b77bd2e43057d621b831261d6 301 Pfam PF16147 Domain of unknown function (DUF4855) 118 246 1.3E-7 T 31-10-2018 IPR032329 Protein of unknown function DUF4855 TK0037 cbab91787b049a3f9a88a65f4b63edd0 319 Pfam PF08241 Methyltransferase domain 164 260 7.3E-11 T 31-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 TK0037 cbab91787b049a3f9a88a65f4b63edd0 319 SUPERFAMILY SSF53335 121 284 3.93E-29 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TK0037 cbab91787b049a3f9a88a65f4b63edd0 319 Gene3D G3DSA:3.40.50.150 128 312 1.1E-25 T 31-10-2018 TK0519 471c4f8fa87ac3723fef1810d4764e2c 205 Pfam PF01205 Uncharacterized protein family UPF0029 17 123 1.2E-32 T 31-10-2018 IPR001498 Impact, N-terminal TK0519 471c4f8fa87ac3723fef1810d4764e2c 205 Pfam PF09186 Domain of unknown function (DUF1949) 139 194 5.9E-15 T 31-10-2018 IPR015269 Uncharacterised domain UPF0029, Impact, C-terminal TK0519 471c4f8fa87ac3723fef1810d4764e2c 205 TIGRFAM TIGR00257 IMPACT_YIGZ: uncharacterized protein, YigZ family 3 198 2.6E-52 T 31-10-2018 IPR015796 Impact family, bacterial/archaeal TK0519 471c4f8fa87ac3723fef1810d4764e2c 205 ProSitePatterns PS00910 Uncharacterized protein family UPF0029 signature. 78 107 - T 31-10-2018 IPR020569 Uncharacterised protein family UPF0029, Impact, conserved site TK0519 471c4f8fa87ac3723fef1810d4764e2c 205 Gene3D G3DSA:3.30.230.30 2 131 3.3E-47 T 31-10-2018 IPR036956 Impact, N-terminal domain superfamily TK0519 471c4f8fa87ac3723fef1810d4764e2c 205 SUPERFAMILY SSF54980 136 198 1.73E-10 T 31-10-2018 IPR035647 EF-G domain III/V-like TK0519 471c4f8fa87ac3723fef1810d4764e2c 205 SUPERFAMILY SSF54211 3 130 3.6E-42 T 31-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TK1514 d10e120a0063d1c0f27fced6d00f525c 193 TIGRFAM TIGR02173 cyt_kin_arch: putative cytidylate kinase 6 175 1.8E-62 T 31-10-2018 IPR011892 Cytidylate kinase, putative GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 TK1514 d10e120a0063d1c0f27fced6d00f525c 193 Hamap MF_00239 Cytidylate kinase [cmk]. 6 178 47.867 T 31-10-2018 IPR011892 Cytidylate kinase, putative GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 TK1514 d10e120a0063d1c0f27fced6d00f525c 193 Pfam PF13189 Cytidylate kinase-like family 7 160 1.3E-25 T 31-10-2018 TK1514 d10e120a0063d1c0f27fced6d00f525c 193 SUPERFAMILY SSF52540 7 175 8.26E-23 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK1514 d10e120a0063d1c0f27fced6d00f525c 193 Gene3D G3DSA:3.40.50.300 2 177 7.0E-46 T 31-10-2018 TK0107 669849cd2f524838a5ffa0ca12faf600 147 Gene3D G3DSA:1.10.10.10 3 68 1.7E-25 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TK0107 669849cd2f524838a5ffa0ca12faf600 147 SMART SM00529 25 124 3.3E-41 T 31-10-2018 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 TK0107 669849cd2f524838a5ffa0ca12faf600 147 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 3 58 1.2E-17 T 31-10-2018 IPR022687 DTXR-type HTH domain GO:0003677 TK0107 669849cd2f524838a5ffa0ca12faf600 147 Gene3D G3DSA:1.10.60.10 69 123 2.0E-20 T 31-10-2018 IPR036421 Iron dependent repressor, metal binding and dimerisation domain superfamily GO:0046914|GO:0046983 TK0107 669849cd2f524838a5ffa0ca12faf600 147 SUPERFAMILY SSF47979 64 137 2.35E-18 T 31-10-2018 IPR036421 Iron dependent repressor, metal binding and dimerisation domain superfamily GO:0046914|GO:0046983 TK0107 669849cd2f524838a5ffa0ca12faf600 147 SUPERFAMILY SSF46785 4 63 5.27E-16 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TK0107 669849cd2f524838a5ffa0ca12faf600 147 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 64 129 5.8E-21 T 31-10-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 TK1222 0e7645735a2a61f6c2c2f8b8e6e3f7d6 238 Pfam PF04039 Domain related to MnhB subunit of Na+/H+ antiporter 101 224 4.3E-24 T 31-10-2018 IPR007182 Na+/H+ antiporter MnhB subunit-related protein TK0803 4c44104c5ccf24a8eede39fa0744e66c 263 SMART SM00382 28 222 1.4E-14 T 31-10-2018 IPR003593 AAA+ ATPase domain TK0803 4c44104c5ccf24a8eede39fa0744e66c 263 SUPERFAMILY SSF52540 4 228 4.0E-57 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK0803 4c44104c5ccf24a8eede39fa0744e66c 263 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TK0803 4c44104c5ccf24a8eede39fa0744e66c 263 Gene3D G3DSA:3.40.50.300 1 243 9.9E-63 T 31-10-2018 TK0803 4c44104c5ccf24a8eede39fa0744e66c 263 Pfam PF00005 ABC transporter 19 165 4.7E-28 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TK1993 b5aa600c703e6a8c543b7ca85bd03653 338 SUPERFAMILY SSF56042 157 332 2.84E-47 T 31-10-2018 IPR036676 PurM-like, C-terminal domain superfamily TK1993 b5aa600c703e6a8c543b7ca85bd03653 338 Gene3D G3DSA:3.90.650.10 156 338 1.5E-56 T 31-10-2018 IPR036676 PurM-like, C-terminal domain superfamily TK1993 b5aa600c703e6a8c543b7ca85bd03653 338 Pfam PF00586 AIR synthase related protein, N-terminal domain 42 151 6.6E-17 T 31-10-2018 IPR016188 PurM-like, N-terminal domain TK1993 b5aa600c703e6a8c543b7ca85bd03653 338 TIGRFAM TIGR02124 hypE: hydrogenase expression/formation protein HypE 4 338 2.0E-119 T 31-10-2018 IPR011854 Carbamoyl dehydratase HypE TK1993 b5aa600c703e6a8c543b7ca85bd03653 338 PIRSF PIRSF005644 1 338 5.8E-124 T 31-10-2018 IPR011854 Carbamoyl dehydratase HypE TK1993 b5aa600c703e6a8c543b7ca85bd03653 338 Pfam PF02769 AIR synthase related protein, C-terminal domain 162 314 1.8E-31 T 31-10-2018 IPR010918 PurM-like, C-terminal domain TK1993 b5aa600c703e6a8c543b7ca85bd03653 338 SUPERFAMILY SSF55326 6 154 1.6E-33 T 31-10-2018 IPR036921 PurM-like, N-terminal domain superfamily TK1993 b5aa600c703e6a8c543b7ca85bd03653 338 Gene3D G3DSA:3.30.1330.10 1 155 1.7E-45 T 31-10-2018 IPR036921 PurM-like, N-terminal domain superfamily TK1356 34a9d63ad04bf91cf34926d8dfc5e871 233 Gene3D G3DSA:3.40.50.300 11 232 4.7E-33 T 31-10-2018 TK1356 34a9d63ad04bf91cf34926d8dfc5e871 233 Pfam PF01935 Domain of unknown function DUF87 16 46 4.2E-5 T 31-10-2018 IPR002789 Helicase HerA, central domain TK1356 34a9d63ad04bf91cf34926d8dfc5e871 233 SUPERFAMILY SSF52540 8 193 8.56E-17 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK0645 d2471c9295a3cef8c2168bedf0690e75 327 Gene3D G3DSA:3.90.1640.10 6 197 1.8E-36 T 31-10-2018 TK0645 d2471c9295a3cef8c2168bedf0690e75 327 SUPERFAMILY SSF64182 17 322 5.89E-50 T 31-10-2018 IPR038763 DHH phosphoesterase superfamily TK0645 d2471c9295a3cef8c2168bedf0690e75 327 Pfam PF02272 DHHA1 domain 207 318 7.2E-13 T 31-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 TK0645 d2471c9295a3cef8c2168bedf0690e75 327 Pfam PF01368 DHH family 19 153 4.3E-11 T 31-10-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 TK0645 d2471c9295a3cef8c2168bedf0690e75 327 Gene3D G3DSA:3.10.310.40 219 321 2.6E-7 T 31-10-2018 TK1343 0e0d9bb317b31a8960087d596144eb96 185 Pfam PF13470 PIN domain 7 132 9.9E-15 T 31-10-2018 IPR002716 PIN domain TK1343 0e0d9bb317b31a8960087d596144eb96 185 TIGRFAM TIGR00305 TIGR00305: putative toxin-antitoxin system toxin component, PIN family 7 131 1.1E-9 T 31-10-2018 IPR002850 PIN family, putative toxin-antitoxin system toxin component TK2186 5273b451f4e3824e67925e4c338f79db 140 SUPERFAMILY SSF103481 41 139 8.24E-12 T 31-10-2018 TK2186 5273b451f4e3824e67925e4c338f79db 140 Pfam PF00892 EamA-like transporter family 6 139 5.4E-23 T 31-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TK2031 9bf708f211a4b4770a3671f550091a6f 91 PRINTS PR00112 Acylphosphatase signature 26 51 1.2E-9 T 31-10-2018 IPR020456 Acylphosphatase GO:0003998 KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 TK2031 9bf708f211a4b4770a3671f550091a6f 91 PRINTS PR00112 Acylphosphatase signature 5 20 1.2E-9 T 31-10-2018 IPR020456 Acylphosphatase GO:0003998 KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 TK2031 9bf708f211a4b4770a3671f550091a6f 91 Pfam PF00708 Acylphosphatase 7 88 3.2E-28 T 31-10-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 TK2031 9bf708f211a4b4770a3671f550091a6f 91 ProSitePatterns PS00151 Acylphosphatase signature 2. 34 50 - T 31-10-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 TK2031 9bf708f211a4b4770a3671f550091a6f 91 Gene3D G3DSA:3.30.70.100 1 91 8.9E-38 T 31-10-2018 TK2031 9bf708f211a4b4770a3671f550091a6f 91 SUPERFAMILY SSF54975 2 90 2.4E-31 T 31-10-2018 IPR036046 Acylphosphatase-like domain superfamily KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 TK2031 9bf708f211a4b4770a3671f550091a6f 91 ProSitePatterns PS00150 Acylphosphatase signature 1. 10 20 - T 31-10-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 TK0355 0c49824bc16fae96c9bddb58aaf0ae5d 309 SMART SM00382 30 213 1.1E-13 T 31-10-2018 IPR003593 AAA+ ATPase domain TK0355 0c49824bc16fae96c9bddb58aaf0ae5d 309 Pfam PF00005 ABC transporter 22 165 8.3E-31 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TK0355 0c49824bc16fae96c9bddb58aaf0ae5d 309 Pfam PF13732 Domain of unknown function (DUF4162) 218 302 9.4E-10 T 31-10-2018 IPR025302 Domain of unknown function DUF4162 TK0355 0c49824bc16fae96c9bddb58aaf0ae5d 309 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TK0355 0c49824bc16fae96c9bddb58aaf0ae5d 309 SUPERFAMILY SSF52540 6 227 1.2E-61 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK0355 0c49824bc16fae96c9bddb58aaf0ae5d 309 Gene3D G3DSA:3.40.50.300 1 240 3.2E-68 T 31-10-2018 TK1999 d4adccea06fdd9d804ffbedd6c75a073 174 SUPERFAMILY SSF47240 1 160 8.13E-60 T 31-10-2018 IPR009078 Ferritin-like superfamily TK1999 d4adccea06fdd9d804ffbedd6c75a073 174 Pfam PF00210 Ferritin-like domain 7 142 6.5E-45 T 31-10-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 TK1999 d4adccea06fdd9d804ffbedd6c75a073 174 Gene3D G3DSA:1.20.1260.10 1 168 3.5E-54 T 31-10-2018 IPR012347 Ferritin-like TK1340 411787be3fe5f67646b585fa657c509d 119 Pfam PF09946 Predicted membrane protein (DUF2178) 8 75 7.4E-8 T 31-10-2018 IPR019235 Protein of unknown function DUF2178, transmembrane TK1820 5c2e3eb4e5b34cc98e45571017b8bea3 386 Pfam PF02163 Peptidase family M50 124 373 6.9E-22 T 31-10-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 TK1820 5c2e3eb4e5b34cc98e45571017b8bea3 386 Gene3D G3DSA:2.30.42.10 213 300 2.3E-25 T 31-10-2018 TK1820 5c2e3eb4e5b34cc98e45571017b8bea3 386 SMART SM00228 199 272 3.7E-12 T 31-10-2018 IPR001478 PDZ domain GO:0005515 TK1820 5c2e3eb4e5b34cc98e45571017b8bea3 386 PRINTS PR01000 Sterol regulatory element binding protein site 2 protease (M50) signature 132 146 1.3E-20 T 31-10-2018 IPR001193 Membrane-bound transcription factor site-2 protease GO:0004222|GO:0006508|GO:0016020 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 TK1820 5c2e3eb4e5b34cc98e45571017b8bea3 386 PRINTS PR01000 Sterol regulatory element binding protein site 2 protease (M50) signature 148 163 1.3E-20 T 31-10-2018 IPR001193 Membrane-bound transcription factor site-2 protease GO:0004222|GO:0006508|GO:0016020 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 TK1820 5c2e3eb4e5b34cc98e45571017b8bea3 386 PRINTS PR01000 Sterol regulatory element binding protein site 2 protease (M50) signature 112 131 1.3E-20 T 31-10-2018 IPR001193 Membrane-bound transcription factor site-2 protease GO:0004222|GO:0006508|GO:0016020 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 TK1820 5c2e3eb4e5b34cc98e45571017b8bea3 386 PRINTS PR01000 Sterol regulatory element binding protein site 2 protease (M50) signature 164 176 1.3E-20 T 31-10-2018 IPR001193 Membrane-bound transcription factor site-2 protease GO:0004222|GO:0006508|GO:0016020 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 TK1820 5c2e3eb4e5b34cc98e45571017b8bea3 386 Pfam PF13180 PDZ domain 215 281 4.4E-14 T 31-10-2018 IPR001478 PDZ domain GO:0005515 TK1820 5c2e3eb4e5b34cc98e45571017b8bea3 386 SUPERFAMILY SSF50156 213 301 2.63E-24 T 31-10-2018 IPR036034 PDZ superfamily GO:0005515 TK1896 5d9cbea710106e8c87c80a83ce77dd97 242 Pfam PF09754 PAC2 family 19 222 7.2E-47 T 31-10-2018 IPR019151 Proteasome assembly chaperone 2 TK1896 5d9cbea710106e8c87c80a83ce77dd97 242 TIGRFAM TIGR00161 TIGR00161: TIGR00161 family protein 9 235 1.6E-64 T 31-10-2018 IPR004425 Conserved hypothetical protein CHP00061 TK1896 5d9cbea710106e8c87c80a83ce77dd97 242 Gene3D G3DSA:3.40.50.10900 1 242 7.2E-74 T 31-10-2018 IPR038389 Proteasome assembly chaperone 2 superfamily TK1896 5d9cbea710106e8c87c80a83ce77dd97 242 SUPERFAMILY SSF159659 11 239 3.01E-49 T 31-10-2018 TK0881 2a32f2c58db70a9d0d9347287a479003 149 Pfam PF00582 Universal stress protein family 2 149 2.9E-20 T 31-10-2018 IPR006016 UspA TK0881 2a32f2c58db70a9d0d9347287a479003 149 Gene3D G3DSA:3.40.50.620 1 149 3.4E-27 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TK0881 2a32f2c58db70a9d0d9347287a479003 149 SUPERFAMILY SSF52402 2 149 9.21E-24 T 31-10-2018 TK1907 2b33e679ad6c4d8056e3e95bd0289322 212 Pfam PF02676 Methyltransferase TYW3 3 184 2.9E-40 T 31-10-2018 IPR003827 tRNA wybutosine-synthesizing protein MetaCyc: PWY-7286|Reactome: R-HSA-6782861 TK1907 2b33e679ad6c4d8056e3e95bd0289322 212 Hamap MF_00266 tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase [taw3]. 1 186 27.442 T 31-10-2018 IPR022908 tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase GO:0008175|GO:0030488|GO:0031591 MetaCyc: PWY-7286 TK1907 2b33e679ad6c4d8056e3e95bd0289322 212 Gene3D G3DSA:3.30.1960.10 1 184 3.2E-50 T 31-10-2018 IPR036602 tRNA wybutosine-synthesizing-like superfamily MetaCyc: PWY-7286|Reactome: R-HSA-6782861 TK1907 2b33e679ad6c4d8056e3e95bd0289322 212 SUPERFAMILY SSF111278 2 183 2.88E-50 T 31-10-2018 IPR036602 tRNA wybutosine-synthesizing-like superfamily MetaCyc: PWY-7286|Reactome: R-HSA-6782861 TK1792 6d3f1e2a181209f27ba1ec67edcd7902 281 SUPERFAMILY SSF103481 185 278 1.96E-13 T 31-10-2018 TK1792 6d3f1e2a181209f27ba1ec67edcd7902 281 Pfam PF00892 EamA-like transporter family 150 276 1.9E-19 T 31-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TK1792 6d3f1e2a181209f27ba1ec67edcd7902 281 Pfam PF00892 EamA-like transporter family 7 137 2.2E-14 T 31-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TK1792 6d3f1e2a181209f27ba1ec67edcd7902 281 SUPERFAMILY SSF103481 42 139 1.44E-13 T 31-10-2018 TK1830 f0795b58597e4a33f6f63276c3ca938c 361 Gene3D G3DSA:3.20.110.20 2 313 2.0E-27 T 31-10-2018 TK1830 f0795b58597e4a33f6f63276c3ca938c 361 SUPERFAMILY SSF88713 3 307 3.15E-47 T 31-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 TK1830 f0795b58597e4a33f6f63276c3ca938c 361 Pfam PF03065 Glycosyl hydrolase family 57 4 314 2.6E-47 T 31-10-2018 IPR004300 Glycoside hydrolase family 57, N-terminal domain GO:0003824|GO:0005975 TK1944 65aea61b2cb29abdf70ed59fae8da997 258 Pfam PF01966 HD domain 84 171 1.5E-4 T 31-10-2018 IPR006674 HD domain TK1944 65aea61b2cb29abdf70ed59fae8da997 258 SMART SM00471 48 181 0.0039 T 31-10-2018 IPR003607 HD/PDEase domain TK1944 65aea61b2cb29abdf70ed59fae8da997 258 SUPERFAMILY SSF109604 14 176 6.02E-9 T 31-10-2018 TK1944 65aea61b2cb29abdf70ed59fae8da997 258 Gene3D G3DSA:1.10.3210.10 13 202 1.8E-7 T 31-10-2018 TK1426 93d3fb30ad1264b1771ecbdf2061a8a5 229 Hamap MF_00170 Ribose-5-phosphate isomerase A [rpiA]. 3 227 36.341 T 31-10-2018 IPR020672 Ribose-5-phosphate isomerase, type A, subgroup GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 TK1426 93d3fb30ad1264b1771ecbdf2061a8a5 229 SUPERFAMILY SSF75445 133 209 7.19E-25 T 31-10-2018 TK1426 93d3fb30ad1264b1771ecbdf2061a8a5 229 Pfam PF06026 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) 53 223 6.6E-66 T 31-10-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 TK1426 93d3fb30ad1264b1771ecbdf2061a8a5 229 Gene3D G3DSA:3.30.70.260 129 207 7.3E-90 T 31-10-2018 TK1426 93d3fb30ad1264b1771ecbdf2061a8a5 229 SUPERFAMILY SSF100950 1 152 8.72E-47 T 31-10-2018 IPR037171 NagB/RpiA transferase-like TK1426 93d3fb30ad1264b1771ecbdf2061a8a5 229 TIGRFAM TIGR00021 rpiA: ribose 5-phosphate isomerase A 6 225 7.0E-83 T 31-10-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 TK1426 93d3fb30ad1264b1771ecbdf2061a8a5 229 Gene3D G3DSA:3.40.50.1360 7 223 7.3E-90 T 31-10-2018 TK0045 b1a74f74ab0b5f8b3f6c499148c76814 174 PIRSF PIRSF024658 1 174 3.7E-93 T 31-10-2018 IPR016825 Flagella-related protein F TK0045 b1a74f74ab0b5f8b3f6c499148c76814 174 Pfam PF01917 Archaebacterial flagellin 4 152 1.4E-21 T 31-10-2018 IPR002774 Flagellin, archaea GO:0005198|GO:0006928 TK0051 833228481dcefc9c5646dbc5e0b5ba1e 170 Gene3D G3DSA:3.40.50.150 2 170 4.0E-80 T 31-10-2018 TK0051 833228481dcefc9c5646dbc5e0b5ba1e 170 ProSitePatterns PS01279 Protein-L-isoaspartate(D-aspartate) O-methyltransferase signature. 133 148 - T 31-10-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 TK0051 833228481dcefc9c5646dbc5e0b5ba1e 170 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 10 169 4.0E-58 T 31-10-2018 TK0051 833228481dcefc9c5646dbc5e0b5ba1e 170 SUPERFAMILY SSF53335 2 169 8.36E-51 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TK0051 833228481dcefc9c5646dbc5e0b5ba1e 170 TIGRFAM TIGR00080 pimt: protein-L-isoaspartate O-methyltransferase 8 169 1.9E-56 T 31-10-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 TK0698 2ac7eb52a4708df63099da5c90f52423 440 Pfam PF01523 Putative modulator of DNA gyrase 22 303 6.7E-50 T 31-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 TK0698 2ac7eb52a4708df63099da5c90f52423 440 Gene3D G3DSA:3.30.2290.10 3 209 1.3E-17 T 31-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal TK0698 2ac7eb52a4708df63099da5c90f52423 440 SUPERFAMILY SSF111283 3 436 4.84E-95 T 31-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 TK1058 cdeb9709cc2d3af40c016d4fb0c7b311 61 Gene3D G3DSA:1.10.10.10 2 55 2.5E-7 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TK1058 cdeb9709cc2d3af40c016d4fb0c7b311 61 SUPERFAMILY SSF46785 4 51 5.17E-7 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TK1114 5163167403f8b76ece0c5f11bddf93f6 314 Pfam PF12706 Beta-lactamase superfamily domain 197 263 2.1E-7 T 31-10-2018 IPR001279 Metallo-beta-lactamase TK1114 5163167403f8b76ece0c5f11bddf93f6 314 Pfam PF12706 Beta-lactamase superfamily domain 32 152 1.9E-10 T 31-10-2018 IPR001279 Metallo-beta-lactamase TK1114 5163167403f8b76ece0c5f11bddf93f6 314 Hamap MF_01818 Ribonuclease BN [rbn]. 2 299 34.691 T 31-10-2018 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 TK1114 5163167403f8b76ece0c5f11bddf93f6 314 SMART SM00849 19 207 1.1E-6 T 31-10-2018 IPR001279 Metallo-beta-lactamase TK1114 5163167403f8b76ece0c5f11bddf93f6 314 SUPERFAMILY SSF56281 3 298 1.15E-76 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TK1114 5163167403f8b76ece0c5f11bddf93f6 314 Gene3D G3DSA:3.60.15.10 1 299 3.4E-84 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TK1114 5163167403f8b76ece0c5f11bddf93f6 314 TIGRFAM TIGR02651 RNase_Z: ribonuclease Z 3 290 1.1E-99 T 31-10-2018 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 TK1881 dfda0e7aa97fcfa1fe82e46081f707af 193 Gene3D G3DSA:1.10.10.10 1 89 7.6E-32 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TK1881 dfda0e7aa97fcfa1fe82e46081f707af 193 SUPERFAMILY SSF46785 1 165 1.01E-35 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TK1881 dfda0e7aa97fcfa1fe82e46081f707af 193 Gene3D G3DSA:1.10.20.10 90 191 6.2E-53 T 31-10-2018 IPR009072 Histone-fold GO:0046982 TK1881 dfda0e7aa97fcfa1fe82e46081f707af 193 SMART SM00418 11 105 1.1E-10 T 31-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TK1881 dfda0e7aa97fcfa1fe82e46081f707af 193 Pfam PF01022 Bacterial regulatory protein, arsR family 19 63 1.1E-15 T 31-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TK1448 4f6ec62e304a5efd5e35a2f005c63f2d 352 Gene3D G3DSA:3.20.20.220 76 337 7.8E-17 T 31-10-2018 TK1448 4f6ec62e304a5efd5e35a2f005c63f2d 352 SUPERFAMILY SSF51730 81 320 1.39E-28 T 31-10-2018 IPR029041 FAD-linked oxidoreductase-like TK1448 4f6ec62e304a5efd5e35a2f005c63f2d 352 Pfam PF12225 Methylene-tetrahydrofolate reductase C terminal 6 43 2.2E-10 T 31-10-2018 IPR022026 Methylene-tetrahydrofolate reductase C-terminal TK1448 4f6ec62e304a5efd5e35a2f005c63f2d 352 Pfam PF02219 Methylenetetrahydrofolate reductase 109 285 8.2E-7 T 31-10-2018 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 TK1779 a724ee5344df624570d9cd897445de30 624 TIGRFAM TIGR00733 TIGR00733: oligopeptide transporter, OPT family 15 591 1.7E-254 T 31-10-2018 IPR004814 Oligopeptide transporter OPT TK1779 a724ee5344df624570d9cd897445de30 624 Pfam PF03169 OPT oligopeptide transporter protein 15 589 4.4E-104 T 31-10-2018 IPR004813 Oligopeptide transporter, OPT superfamily GO:0055085 TK1779 a724ee5344df624570d9cd897445de30 624 TIGRFAM TIGR00728 OPT_sfam: oligopeptide transporter, OPT superfamily 10 593 9.8E-122 T 31-10-2018 IPR004813 Oligopeptide transporter, OPT superfamily GO:0055085 TK1698 585499e81d0f89cd3ce20831aa896d21 67 Hamap MF_00949 Transcription elongation factor Spt4 [spt4]. 6 67 25.422 T 31-10-2018 IPR007178 Archaeal transcription elongation factor Spt4 GO:0006355 TK1698 585499e81d0f89cd3ce20831aa896d21 67 ProDom PD019197 RNA DNA-DIRECTED POLYMERASE SUBUNIT E'' POLYMERASE RPOE2 TRANSFERASE NUCLEOTIDYLTRANSFERASE E 19 66 6.0E-21 T 31-10-2018 IPR007178 Archaeal transcription elongation factor Spt4 GO:0006355 TK1698 585499e81d0f89cd3ce20831aa896d21 67 SUPERFAMILY SSF63393 3 67 2.59E-17 T 31-10-2018 IPR029040 RNA polymerase subunit RPABC4/transcription elongation factor Spt4 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-75955 TK1698 585499e81d0f89cd3ce20831aa896d21 67 Gene3D G3DSA:2.20.28.90 1 67 1.0E-27 T 31-10-2018 IPR038589 Archaeal transcription elongation factor Spt4 superfamily TK1698 585499e81d0f89cd3ce20831aa896d21 67 SMART SM01389 4 67 1.2E-23 T 31-10-2018 IPR022800 Spt4/RpoE2 zinc finger Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-75955 TK1698 585499e81d0f89cd3ce20831aa896d21 67 Pfam PF06093 Spt4/RpoE2 zinc finger 4 67 4.8E-12 T 31-10-2018 IPR022800 Spt4/RpoE2 zinc finger Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-75955 TK1203 3d7a65a6d9b28cf0a9506c85946b13bb 157 SUPERFAMILY SSF52980 2 119 8.58E-5 T 31-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 TK1203 3d7a65a6d9b28cf0a9506c85946b13bb 157 Pfam PF09002 Domain of unknown function (DUF1887) 1 125 1.1E-6 T 31-10-2018 IPR015093 Protein of unknown function DUF1887 TK1646 e23c3dcc1adbedba29978bbb99c79a7a 227 Pfam PF13680 Protein of unknown function (DUF4152) 1 224 1.4E-138 T 31-10-2018 IPR025206 Protein of unknown function DUF4152 TK1646 e23c3dcc1adbedba29978bbb99c79a7a 227 Gene3D G3DSA:3.30.420.440 1 227 3.7E-108 T 31-10-2018 TK0903 2c0828d5e5d3e12a3bd329388a373694 393 Gene3D G3DSA:3.30.70.2510 162 275 8.0E-31 T 31-10-2018 TK0903 2c0828d5e5d3e12a3bd329388a373694 393 SUPERFAMILY SSF55120 272 383 4.68E-13 T 31-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 TK0903 2c0828d5e5d3e12a3bd329388a373694 393 TIGRFAM TIGR01213 pseudo_Pus10arc: tRNA pseudouridine(54/55) synthase 7 386 2.0E-150 T 31-10-2018 IPR005912 tRNA pseudouridine synthase, Pus10 GO:0000049|GO:0001522|GO:0006400|GO:0009982 TK0903 2c0828d5e5d3e12a3bd329388a373694 393 Gene3D G3DSA:3.30.70.3190 276 384 4.5E-29 T 31-10-2018 TK0903 2c0828d5e5d3e12a3bd329388a373694 393 Hamap MF_01893 tRNA pseudouridine synthase Pus10 [pus10]. 7 385 53.446 T 31-10-2018 IPR005912 tRNA pseudouridine synthase, Pus10 GO:0000049|GO:0001522|GO:0006400|GO:0009982 TK0903 2c0828d5e5d3e12a3bd329388a373694 393 Pfam PF02926 THUMP domain 55 162 3.1E-13 T 31-10-2018 IPR004114 THUMP domain GO:0003723 TK2236 47398b2ef818492bac0d9a7de9c5453b 158 TIGRFAM TIGR01685 MDP-1: magnesium-dependent phosphatase-1 2 152 1.7E-26 T 31-10-2018 IPR010036 Magnesium-dependent phosphatase-1, eukaryotic/archaeal-type GO:0016791 TK2236 47398b2ef818492bac0d9a7de9c5453b 158 Gene3D G3DSA:3.40.50.1000 1 158 4.7E-28 T 31-10-2018 IPR023214 HAD superfamily TK2236 47398b2ef818492bac0d9a7de9c5453b 158 SUPERFAMILY SSF56784 2 128 8.54E-18 T 31-10-2018 IPR036412 HAD-like superfamily TK2236 47398b2ef818492bac0d9a7de9c5453b 158 Pfam PF03031 NLI interacting factor-like phosphatase 3 157 6.3E-8 T 31-10-2018 IPR004274 FCP1 homology domain TK2236 47398b2ef818492bac0d9a7de9c5453b 158 TIGRFAM TIGR01681 HAD-SF-IIIC: HAD phosphatase, family IIIC 3 130 1.3E-16 T 31-10-2018 IPR010033 HAD-superfamily phosphatase, subfamily IIIC TK2299 d6eab8e4a5af537f985d19ae2289ecc8 236 Gene3D G3DSA:3.20.20.70 3 181 1.8E-21 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TK2299 d6eab8e4a5af537f985d19ae2289ecc8 236 SUPERFAMILY SSF102114 26 170 1.07E-20 T 31-10-2018 TK2299 d6eab8e4a5af537f985d19ae2289ecc8 236 Pfam PF04055 Radical SAM superfamily 26 168 1.2E-14 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TK2299 d6eab8e4a5af537f985d19ae2289ecc8 236 Pfam PF13353 4Fe-4S single cluster domain 18 104 1.0E-8 T 31-10-2018 TK2299 d6eab8e4a5af537f985d19ae2289ecc8 236 TIGRFAM TIGR02495 NrdG2: anaerobic ribonucleoside-triphosphate reductase activating protein 3 190 8.0E-51 T 31-10-2018 IPR012840 Anaerobic ribonucleoside-triphosphate reductase activating protein TK0368 d3fa4ee457a8d2bd19b475c5a3d0c61c 381 Gene3D G3DSA:3.30.70.1510 2 84 2.9E-32 T 31-10-2018 TK0368 d3fa4ee457a8d2bd19b475c5a3d0c61c 381 SUPERFAMILY SSF143437 2 176 8.72E-48 T 31-10-2018 TK0368 d3fa4ee457a8d2bd19b475c5a3d0c61c 381 SUPERFAMILY SSF52402 178 337 4.85E-50 T 31-10-2018 TK0368 d3fa4ee457a8d2bd19b475c5a3d0c61c 381 Gene3D G3DSA:3.30.2300.10 85 166 3.6E-30 T 31-10-2018 TK0368 d3fa4ee457a8d2bd19b475c5a3d0c61c 381 Gene3D G3DSA:3.40.50.620 178 375 7.3E-66 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TK0368 d3fa4ee457a8d2bd19b475c5a3d0c61c 381 Pfam PF02926 THUMP domain 29 168 3.1E-27 T 31-10-2018 IPR004114 THUMP domain GO:0003723 TK0368 d3fa4ee457a8d2bd19b475c5a3d0c61c 381 TIGRFAM TIGR00342 TIGR00342: tRNA sulfurtransferase ThiI 5 366 3.1E-104 T 31-10-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 KEGG: 00730+2.8.1.4 TK0368 d3fa4ee457a8d2bd19b475c5a3d0c61c 381 Hamap MF_00021 tRNA sulfurtransferase [thiI]. 1 381 126.438 T 31-10-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 KEGG: 00730+2.8.1.4 TK0368 d3fa4ee457a8d2bd19b475c5a3d0c61c 381 Pfam PF02568 Thiamine biosynthesis protein (ThiI) 178 368 1.4E-65 T 31-10-2018 IPR020536 Thil, AANH domain GO:0004810 KEGG: 00730+2.8.1.4 TK0368 d3fa4ee457a8d2bd19b475c5a3d0c61c 381 SMART SM00981 74 168 1.6E-20 T 31-10-2018 IPR004114 THUMP domain GO:0003723 TK0648 53febd7a6a001427b8aec64871391855 394 Gene3D G3DSA:1.25.40.10 1 348 4.4E-54 T 31-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TK0648 53febd7a6a001427b8aec64871391855 394 SUPERFAMILY SSF48452 46 339 4.55E-6 T 31-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TK1080 d61c8b870c673f4e4810f9c1fd10ed80 102 Hamap MF_00481 50S ribosomal protein L30e [rpl30e]. 2 99 29.669 T 31-10-2018 IPR000231 Ribosomal protein L30e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1080 d61c8b870c673f4e4810f9c1fd10ed80 102 Gene3D G3DSA:3.30.1330.30 1 101 1.2E-38 T 31-10-2018 IPR029064 50S ribosomal protein L30e-like TK1080 d61c8b870c673f4e4810f9c1fd10ed80 102 Pfam PF01248 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family 7 95 7.0E-20 T 31-10-2018 IPR004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45 TK1080 d61c8b870c673f4e4810f9c1fd10ed80 102 ProSitePatterns PS00993 Ribosomal protein L30e signature 2. 70 90 - T 31-10-2018 IPR022991 Ribosomal protein L30e, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1080 d61c8b870c673f4e4810f9c1fd10ed80 102 SUPERFAMILY SSF55315 3 97 4.35E-27 T 31-10-2018 IPR029064 50S ribosomal protein L30e-like TK0627 1c0627419858f9401435d441531d18f6 379 Gene3D G3DSA:1.20.1530.20 4 376 1.4E-44 T 31-10-2018 IPR038770 Sodium/solute symporter superfamily TK0627 1c0627419858f9401435d441531d18f6 379 Pfam PF00999 Sodium/hydrogen exchanger family 10 365 1.5E-29 T 31-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 TK0746 eb486ae104e3ee43e19cf6380e9dcd34 262 Gene3D G3DSA:3.40.50.300 1 245 1.7E-74 T 31-10-2018 TK0746 eb486ae104e3ee43e19cf6380e9dcd34 262 Pfam PF00005 ABC transporter 26 161 1.1E-31 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TK0746 eb486ae104e3ee43e19cf6380e9dcd34 262 SUPERFAMILY SSF52540 1 226 2.81E-67 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK0746 eb486ae104e3ee43e19cf6380e9dcd34 262 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TK0746 eb486ae104e3ee43e19cf6380e9dcd34 262 SMART SM00382 25 209 8.7E-16 T 31-10-2018 IPR003593 AAA+ ATPase domain TK0644 f19657804d153767623f80a7e2f2c937 108 Pfam PF11419 Protein of unknown function (DUF3194) 13 95 1.1E-28 T 31-10-2018 IPR024502 Protein of unknown function DUF3194 TK0644 f19657804d153767623f80a7e2f2c937 108 Gene3D G3DSA:3.30.300.100 1 108 3.6E-39 T 31-10-2018 IPR035954 MTH677-like superfamily TK0069 714ef17f7d5538363a9dabab7786fce7 215 Pfam PF12705 PD-(D/E)XK nuclease superfamily 77 205 4.0E-6 T 31-10-2018 IPR038726 PD-(D/E)XK endonuclease-like domain, AddAB-type TK0069 714ef17f7d5538363a9dabab7786fce7 215 Gene3D G3DSA:3.90.320.10 4 209 5.7E-24 T 31-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal TK0069 714ef17f7d5538363a9dabab7786fce7 215 TIGRFAM TIGR00372 cas4: CRISPR-associated protein Cas4 11 207 3.8E-32 T 31-10-2018 IPR013343 CRISPR-associated protein Cas4 TK1456 f952579bd3dab5b2b5f28092c679fcef 197 SUPERFAMILY SSF109755 3 98 1.26E-15 T 31-10-2018 TK1456 f952579bd3dab5b2b5f28092c679fcef 197 Gene3D G3DSA:1.20.58.220 1 110 6.3E-20 T 31-10-2018 IPR038078 PhoU-like domain superfamily TK1456 f952579bd3dab5b2b5f28092c679fcef 197 Gene3D G3DSA:3.30.70.1450 111 191 4.5E-20 T 31-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 TK1456 f952579bd3dab5b2b5f28092c679fcef 197 Pfam PF01895 PhoU domain 11 94 1.0E-9 T 31-10-2018 IPR026022 PhoU domain TK1456 f952579bd3dab5b2b5f28092c679fcef 197 SUPERFAMILY SSF116726 103 175 7.72E-19 T 31-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 TK1456 f952579bd3dab5b2b5f28092c679fcef 197 Pfam PF02080 TrkA-C domain 118 176 2.2E-16 T 31-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 TK0034 a67ec4b998682614da372c93feffb494 247 SUPERFAMILY SSF48371 20 243 2.78E-24 T 31-10-2018 IPR016024 Armadillo-type fold TK0034 a67ec4b998682614da372c93feffb494 247 SMART SM01349 19 239 0.0039 T 31-10-2018 IPR034085 TOG domain TK0034 a67ec4b998682614da372c93feffb494 247 Gene3D G3DSA:1.25.10.10 1 247 5.1E-67 T 31-10-2018 IPR011989 Armadillo-like helical TK0034 a67ec4b998682614da372c93feffb494 247 Pfam PF13646 HEAT repeats 154 238 1.3E-6 T 31-10-2018 TK0851 93aa25764068559d15f8de670d3083d6 58 Gene3D G3DSA:3.40.50.1010 1 47 1.6E-5 T 31-10-2018 TK0851 93aa25764068559d15f8de670d3083d6 58 SUPERFAMILY SSF88723 4 48 3.92E-8 T 31-10-2018 IPR029060 PIN-like domain superfamily TK1224 0cea7744959551c10d9c8507714b9b0d 130 TIGRFAM TIGR01300 CPA3_mnhG_phaG: monovalent cation/proton antiporter, MnhG/PhaG subunit 11 109 1.6E-29 T 31-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 TK1224 0cea7744959551c10d9c8507714b9b0d 130 Pfam PF03334 Na+/H+ antiporter subunit 11 94 1.8E-25 T 31-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 TK1837 8f2c328bb9e14f62ab97408dd35d5b86 117 PIRSF PIRSF016134 2 111 3.3E-48 T 31-10-2018 IPR016645 Uncharacterised conserved protein UCP016134 TK1837 8f2c328bb9e14f62ab97408dd35d5b86 117 SMART SM01022 6 109 9.0E-17 T 31-10-2018 IPR007374 ASCH domain TK1837 8f2c328bb9e14f62ab97408dd35d5b86 117 SUPERFAMILY SSF88697 1 110 5.8E-38 T 31-10-2018 IPR015947 PUA-like superfamily TK1837 8f2c328bb9e14f62ab97408dd35d5b86 117 Gene3D G3DSA:2.30.130.30 2 109 4.0E-44 T 31-10-2018 TK1837 8f2c328bb9e14f62ab97408dd35d5b86 117 Pfam PF04266 ASCH domain 6 108 1.2E-17 T 31-10-2018 IPR007374 ASCH domain TK1557 182fdfcc22412e26de2f0ac6f7ecbbeb 488 Gene3D G3DSA:3.50.50.60 409 463 9.0E-6 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TK1557 182fdfcc22412e26de2f0ac6f7ecbbeb 488 PIRSF PIRSF038984 135 467 3.6E-24 T 31-10-2018 IPR028348 FAD dependent protein TK1557 182fdfcc22412e26de2f0ac6f7ecbbeb 488 PIRSF PIRSF038984 2 93 4.2E-10 T 31-10-2018 IPR028348 FAD dependent protein TK1557 182fdfcc22412e26de2f0ac6f7ecbbeb 488 SUPERFAMILY SSF51905 11 463 3.84E-31 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TK1557 182fdfcc22412e26de2f0ac6f7ecbbeb 488 Pfam PF01134 Glucose inhibited division protein A 385 461 2.6E-4 T 31-10-2018 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 TK1557 182fdfcc22412e26de2f0ac6f7ecbbeb 488 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 419 441 7.0E-10 T 31-10-2018 TK1557 182fdfcc22412e26de2f0ac6f7ecbbeb 488 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 13 32 7.0E-10 T 31-10-2018 TK1557 182fdfcc22412e26de2f0ac6f7ecbbeb 488 Pfam PF01946 Thi4 family 11 41 3.4E-7 T 31-10-2018 TK1557 182fdfcc22412e26de2f0ac6f7ecbbeb 488 Gene3D G3DSA:3.50.50.60 3 97 5.0E-20 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TK1557 182fdfcc22412e26de2f0ac6f7ecbbeb 488 Gene3D G3DSA:3.50.50.60 136 236 3.1E-5 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TK0329 10f0b081ee41afea7e0d5373475b1a55 319 SMART SM00382 44 194 4.0E-5 T 31-10-2018 IPR003593 AAA+ ATPase domain TK0329 10f0b081ee41afea7e0d5373475b1a55 319 Pfam PF03308 ArgK protein 18 281 4.1E-103 T 31-10-2018 TK0329 10f0b081ee41afea7e0d5373475b1a55 319 SUPERFAMILY SSF52540 2 311 4.57E-81 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK0329 10f0b081ee41afea7e0d5373475b1a55 319 TIGRFAM TIGR00750 lao: LAO/AO transport system ATPase 12 312 2.8E-130 T 31-10-2018 IPR005129 SIMIBI class G3E GTPase, ArgK/MeaB GO:0003924|GO:0005525 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 TK0329 10f0b081ee41afea7e0d5373475b1a55 319 Gene3D G3DSA:3.40.50.300 43 252 2.6E-88 T 31-10-2018 TK1321 7c6fe9c66d82bb0ebedb290124ea599b 229 Pfam PF01912 eIF-6 family 5 206 1.1E-69 T 31-10-2018 IPR002769 Translation initiation factor IF6 GO:0042256|GO:0043022 TK1321 7c6fe9c66d82bb0ebedb290124ea599b 229 Gene3D G3DSA:3.75.10.10 1 228 7.2E-79 T 31-10-2018 TK1321 7c6fe9c66d82bb0ebedb290124ea599b 229 Hamap MF_00032 Translation initiation factor 6 [eif6]. 1 229 99.509 T 31-10-2018 IPR002769 Translation initiation factor IF6 GO:0042256|GO:0043022 TK1321 7c6fe9c66d82bb0ebedb290124ea599b 229 SMART SM00654 4 207 1.2E-103 T 31-10-2018 IPR002769 Translation initiation factor IF6 GO:0042256|GO:0043022 TK1321 7c6fe9c66d82bb0ebedb290124ea599b 229 SUPERFAMILY SSF55909 3 227 4.22E-75 T 31-10-2018 TK1321 7c6fe9c66d82bb0ebedb290124ea599b 229 TIGRFAM TIGR00323 eIF-6: putative translation initiation factor eIF-6 5 227 4.1E-63 T 31-10-2018 IPR002769 Translation initiation factor IF6 GO:0042256|GO:0043022 TK1321 7c6fe9c66d82bb0ebedb290124ea599b 229 PIRSF PIRSF006413 2 229 2.1E-78 T 31-10-2018 IPR002769 Translation initiation factor IF6 GO:0042256|GO:0043022 TK0949 abc7ce0eb7073b13e865d53648f0064d 344 Pfam PF13439 Glycosyltransferase Family 4 14 168 7.5E-34 T 31-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 TK0949 abc7ce0eb7073b13e865d53648f0064d 344 Pfam PF00534 Glycosyl transferases group 1 175 321 5.7E-27 T 31-10-2018 IPR001296 Glycosyl transferase, family 1 TK0949 abc7ce0eb7073b13e865d53648f0064d 344 SUPERFAMILY SSF53756 5 343 5.42E-82 T 31-10-2018 TK0949 abc7ce0eb7073b13e865d53648f0064d 344 Gene3D G3DSA:3.40.50.2000 177 326 1.6E-33 T 31-10-2018 TK0949 abc7ce0eb7073b13e865d53648f0064d 344 Gene3D G3DSA:3.40.50.2000 1 176 7.5E-44 T 31-10-2018 TK0317 47eb651098e2910396e6335aca23ceba 252 PIRSF PIRSF005902 1 252 2.0E-58 T 31-10-2018 IPR001130 TatD family GO:0016788 TK0317 47eb651098e2910396e6335aca23ceba 252 Gene3D G3DSA:3.20.20.140 1 251 3.3E-64 T 31-10-2018 TK0317 47eb651098e2910396e6335aca23ceba 252 Pfam PF01026 TatD related DNase 2 248 1.6E-57 T 31-10-2018 IPR001130 TatD family GO:0016788 TK0317 47eb651098e2910396e6335aca23ceba 252 TIGRFAM TIGR00010 TIGR00010: hydrolase, TatD family 1 249 1.2E-69 T 31-10-2018 IPR015991 Uncharacterised hydrolase TatD-type GO:0004536 TK0317 47eb651098e2910396e6335aca23ceba 252 SUPERFAMILY SSF51556 1 250 2.52E-57 T 31-10-2018 IPR032466 Metal-dependent hydrolase TK0317 47eb651098e2910396e6335aca23ceba 252 ProSitePatterns PS01091 TatD deoxyribonuclease family signature 3. 187 203 - T 31-10-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 TK2178 6bc49e7aa521305da416f868aaea5cb3 1256 SUPERFAMILY SSF103647 551 602 5.62E-5 T 31-10-2018 IPR028974 TSP type-3 repeat GO:0005509 Reactome: R-HSA-186797 TK2178 6bc49e7aa521305da416f868aaea5cb3 1256 Pfam PF00932 Lamin Tail Domain 144 264 1.7E-9 T 31-10-2018 IPR001322 Lamin tail domain TK2178 6bc49e7aa521305da416f868aaea5cb3 1256 SUPERFAMILY SSF74853 146 264 1.57E-5 T 31-10-2018 IPR036415 Lamin tail domain superfamily TK0855 d7268088ba79819925ab250c811a7a3a 312 Gene3D G3DSA:3.40.1350.10 14 117 6.3E-6 T 31-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 TK0855 d7268088ba79819925ab250c811a7a3a 312 Pfam PF14088 Domain of unknown function (DUF4268) 171 307 9.0E-22 T 31-10-2018 IPR025364 Domain of unknown function DUF4268 TK1868 a27c42cc5ec91b9fd873133df021af2f 253 Gene3D G3DSA:3.40.50.300 3 251 2.5E-70 T 31-10-2018 TK1868 a27c42cc5ec91b9fd873133df021af2f 253 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 5 253 3.7E-106 T 31-10-2018 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 TK1868 a27c42cc5ec91b9fd873133df021af2f 253 SUPERFAMILY SSF52540 4 240 6.9E-63 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK1868 a27c42cc5ec91b9fd873133df021af2f 253 SMART SM00382 29 225 1.9E-13 T 31-10-2018 IPR003593 AAA+ ATPase domain TK1868 a27c42cc5ec91b9fd873133df021af2f 253 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TK1868 a27c42cc5ec91b9fd873133df021af2f 253 Pfam PF00005 ABC transporter 21 178 1.2E-32 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TK0055 750096a57d9044df215d247bd46a00b8 112 Gene3D G3DSA:2.30.130.30 1 112 3.6E-40 T 31-10-2018 TK0055 750096a57d9044df215d247bd46a00b8 112 SMART SM01022 6 109 4.2E-12 T 31-10-2018 IPR007374 ASCH domain TK0055 750096a57d9044df215d247bd46a00b8 112 PIRSF PIRSF016134 2 111 1.7E-47 T 31-10-2018 IPR016645 Uncharacterised conserved protein UCP016134 TK0055 750096a57d9044df215d247bd46a00b8 112 Pfam PF04266 ASCH domain 7 107 1.4E-14 T 31-10-2018 IPR007374 ASCH domain TK0055 750096a57d9044df215d247bd46a00b8 112 SUPERFAMILY SSF88697 1 108 9.94E-33 T 31-10-2018 IPR015947 PUA-like superfamily TK1760 325a8303137497ed8c042802e873cca5 626 Gene3D G3DSA:3.10.105.10 286 520 1.6E-147 T 31-10-2018 TK1760 325a8303137497ed8c042802e873cca5 626 TIGRFAM TIGR04288 CGP_CTERM: CGP-CTERM domain 606 625 2.0E-7 T 31-10-2018 IPR027552 CGP-CTERM domain TK1760 325a8303137497ed8c042802e873cca5 626 Gene3D G3DSA:3.90.76.10 42 196 1.6E-147 T 31-10-2018 TK1760 325a8303137497ed8c042802e873cca5 626 Gene3D G3DSA:3.40.190.10 31 544 1.6E-147 T 31-10-2018 TK1760 325a8303137497ed8c042802e873cca5 626 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 74 469 1.4E-73 T 31-10-2018 IPR000914 Solute-binding protein family 5 domain TK1760 325a8303137497ed8c042802e873cca5 626 SUPERFAMILY SSF53850 30 549 2.57E-108 T 31-10-2018 TK2047 2d0515f0839a6e1ee362e706c7cd9efb 442 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 10 417 2.4E-50 T 31-10-2018 IPR002823 Protein of unknown function DUF112, transmembrane TK1692 fca527449ded92c091767632f1127c6a 246 Gene3D G3DSA:3.40.50.620 55 198 2.5E-12 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TK1692 fca527449ded92c091767632f1127c6a 246 PIRSF PIRSF006601 1 246 3.1E-84 T 31-10-2018 IPR012096 ATPase, PP-loop, MJ1638-related TK1692 fca527449ded92c091767632f1127c6a 246 SUPERFAMILY SSF52402 50 190 1.72E-18 T 31-10-2018 TK0581 3de7faaf5c7444d872015ec9d83a6bdc 63 Gene3D G3DSA:1.10.10.10 6 59 3.3E-6 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TK0581 3de7faaf5c7444d872015ec9d83a6bdc 63 SUPERFAMILY SSF46785 9 54 3.99E-6 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TK0717 6e0006bf6ca5648ca723ed47e1a0df2a 272 Pfam PF13531 Bacterial extracellular solute-binding protein 43 268 2.7E-43 T 31-10-2018 TK0717 6e0006bf6ca5648ca723ed47e1a0df2a 272 Gene3D G3DSA:3.40.190.10 49 267 2.0E-53 T 31-10-2018 TK0717 6e0006bf6ca5648ca723ed47e1a0df2a 272 SMART SM00062 41 269 8.4E-4 T 31-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF TK0717 6e0006bf6ca5648ca723ed47e1a0df2a 272 Gene3D G3DSA:3.40.190.10 121 229 2.0E-53 T 31-10-2018 TK0717 6e0006bf6ca5648ca723ed47e1a0df2a 272 TIGRFAM TIGR01256 modA: molybdate ABC transporter, periplasmic molybdate-binding protein 48 266 2.1E-23 T 31-10-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689 TK0717 6e0006bf6ca5648ca723ed47e1a0df2a 272 PIRSF PIRSF004846 1 271 1.4E-46 T 31-10-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689 TK0717 6e0006bf6ca5648ca723ed47e1a0df2a 272 SUPERFAMILY SSF53850 40 269 1.18E-52 T 31-10-2018 TK1752 f5fdab4b6b1e2a7779d22ef12c05328b 77 ProDom PD188822 UPF0330 AF1997 ST1125.1 AF1689 AF1478 C1_0043 PYRAB04040 PF1222 MM2475 MA1514 3 49 5.0E-19 T 31-10-2018 IPR003847 Putative antitoxin TK1752 f5fdab4b6b1e2a7779d22ef12c05328b 77 Pfam PF02697 Putative antitoxin 3 69 1.9E-23 T 31-10-2018 IPR003847 Putative antitoxin TK1752 f5fdab4b6b1e2a7779d22ef12c05328b 77 Hamap MF_00794 Putative antitoxin . 2 72 17.134 T 31-10-2018 IPR003847 Putative antitoxin TK1521 1a206c1dea8f4c97c0c772f3291ae8a8 235 TIGRFAM TIGR01020 uS5_euk_arch: ribosomal protein uS5 10 221 3.8E-106 T 31-10-2018 IPR005711 Ribosomal protein S5, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-3214858|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8876725|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1521 1a206c1dea8f4c97c0c772f3291ae8a8 235 Gene3D G3DSA:3.30.230.10 123 214 1.4E-29 T 31-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TK1521 1a206c1dea8f4c97c0c772f3291ae8a8 235 ProSitePatterns PS00585 Ribosomal protein S5 signature. 77 109 - T 31-10-2018 IPR018192 Ribosomal protein S5, N-terminal, conserved site TK1521 1a206c1dea8f4c97c0c772f3291ae8a8 235 SUPERFAMILY SSF54211 138 210 4.8E-19 T 31-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TK1521 1a206c1dea8f4c97c0c772f3291ae8a8 235 Hamap MF_01307_A 30S ribosomal protein S5 [rpsE]. 8 212 48.002 T 31-10-2018 IPR005711 Ribosomal protein S5, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-3214858|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8876725|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1521 1a206c1dea8f4c97c0c772f3291ae8a8 235 Gene3D G3DSA:3.30.160.770 12 122 2.0E-37 T 31-10-2018 TK1521 1a206c1dea8f4c97c0c772f3291ae8a8 235 Pfam PF03719 Ribosomal protein S5, C-terminal domain 145 210 5.3E-21 T 31-10-2018 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 TK1521 1a206c1dea8f4c97c0c772f3291ae8a8 235 Pfam PF00333 Ribosomal protein S5, N-terminal domain 62 123 4.8E-21 T 31-10-2018 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 TK1521 1a206c1dea8f4c97c0c772f3291ae8a8 235 SUPERFAMILY SSF54768 62 125 2.3E-18 T 31-10-2018 TK0770 aca85ca32f85d89c08c00a7edad68d9c 165 Gene3D G3DSA:1.10.10.10 18 113 1.1E-17 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TK0770 aca85ca32f85d89c08c00a7edad68d9c 165 Pfam PF03551 Transcriptional regulator PadR-like family 24 97 1.6E-16 T 31-10-2018 IPR005149 Transcription regulator PadR, N-terminal TK0770 aca85ca32f85d89c08c00a7edad68d9c 165 SUPERFAMILY SSF46785 7 100 3.97E-23 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TK0246 e01d5abb033e54b61b10d3cd8ba4b359 195 PIRSF PIRSF000495 1 195 2.1E-60 T 31-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 TK0246 e01d5abb033e54b61b10d3cd8ba4b359 195 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 2 194 6.3E-63 T 31-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 TK0246 e01d5abb033e54b61b10d3cd8ba4b359 195 SUPERFAMILY SSF52317 2 194 2.72E-49 T 31-10-2018 IPR029062 Class I glutamine amidotransferase-like TK0246 e01d5abb033e54b61b10d3cd8ba4b359 195 Pfam PF00117 Glutamine amidotransferase class-I 36 192 1.7E-19 T 31-10-2018 IPR017926 Glutamine amidotransferase TK0246 e01d5abb033e54b61b10d3cd8ba4b359 195 Hamap MF_00278 Imidazole glycerol phosphate synthase subunit HisH [hisH]. 1 195 34.739 T 31-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 TK0246 e01d5abb033e54b61b10d3cd8ba4b359 195 Gene3D G3DSA:3.40.50.880 1 195 2.1E-64 T 31-10-2018 IPR029062 Class I glutamine amidotransferase-like TK2146 a6efc82cbcd6f9fa00888e01d81443c4 101 Pfam PF11491 Protein of unknown function (DUF3213) 15 98 4.9E-47 T 31-10-2018 IPR021583 Protein of unknown function DUF3213 TK2146 a6efc82cbcd6f9fa00888e01d81443c4 101 Gene3D G3DSA:3.30.70.1750 6 101 6.7E-35 T 31-10-2018 TK2241 5d02560e31d99bfc8d196821e49cdc70 228 SUPERFAMILY SSF53335 5 224 3.16E-40 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TK2241 5d02560e31d99bfc8d196821e49cdc70 228 Gene3D G3DSA:3.40.50.150 1 227 3.6E-71 T 31-10-2018 TK2241 5d02560e31d99bfc8d196821e49cdc70 228 Pfam PF13649 Methyltransferase domain 42 136 2.6E-26 T 31-10-2018 TK1696 c11a76257c592484a1f67bdbc1db323d 98 SUPERFAMILY SSF54189 1 97 1.37E-31 T 31-10-2018 IPR012678 Ribosomal protein L23/L15e core domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 TK1696 c11a76257c592484a1f67bdbc1db323d 98 Pfam PF01282 Ribosomal protein S24e 21 97 1.0E-25 T 31-10-2018 IPR001976 Ribosomal protein S24e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1696 c11a76257c592484a1f67bdbc1db323d 98 Hamap MF_00545 30S ribosomal protein S24e [rps24e]. 1 98 20.842 T 31-10-2018 IPR001976 Ribosomal protein S24e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1696 c11a76257c592484a1f67bdbc1db323d 98 ProDom PD006052 RIBOSOMAL S24 40S RIBONUCLEOPROTEIN S24E 30S S24 CDNA RIKEN ACETYLATION 11 76 4.0E-33 T 31-10-2018 IPR001976 Ribosomal protein S24e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1696 c11a76257c592484a1f67bdbc1db323d 98 ProSitePatterns PS00529 Ribosomal protein S24e signature. 60 82 - T 31-10-2018 IPR018098 Ribosomal S24e conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1696 c11a76257c592484a1f67bdbc1db323d 98 Gene3D G3DSA:3.30.70.330 1 98 3.4E-38 T 31-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily TK1152 5762b1c295902497985b5760cb79be28 312 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TK1152 5762b1c295902497985b5760cb79be28 312 SUPERFAMILY SSF52540 4 224 3.03E-56 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK1152 5762b1c295902497985b5760cb79be28 312 Pfam PF00005 ABC transporter 23 165 4.4E-28 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TK1152 5762b1c295902497985b5760cb79be28 312 SMART SM00382 30 230 7.2E-9 T 31-10-2018 IPR003593 AAA+ ATPase domain TK1152 5762b1c295902497985b5760cb79be28 312 Gene3D G3DSA:3.40.50.300 2 236 2.5E-58 T 31-10-2018 TK2249 6ea49765ebb0c5369d85e255c53503f8 166 SUPERFAMILY SSF48452 19 91 3.09E-6 T 31-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TK2249 6ea49765ebb0c5369d85e255c53503f8 166 Gene3D G3DSA:1.25.40.10 12 165 1.1E-7 T 31-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TK1961 88ed327ef6571b10955ebb18912787c3 356 SUPERFAMILY SSF50249 51 176 1.07E-24 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold TK1961 88ed327ef6571b10955ebb18912787c3 356 SUPERFAMILY SSF50249 179 344 1.71E-15 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold TK1961 88ed327ef6571b10955ebb18912787c3 356 Gene3D G3DSA:2.40.50.140 176 342 1.2E-8 T 31-10-2018 TK1961 88ed327ef6571b10955ebb18912787c3 356 Pfam PF08646 Replication factor-A C terminal domain 193 277 5.8E-7 T 31-10-2018 IPR013955 Replication factor A, C-terminal TK1961 88ed327ef6571b10955ebb18912787c3 356 Pfam PF01336 OB-fold nucleic acid binding domain 73 151 2.9E-11 T 31-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 TK1961 88ed327ef6571b10955ebb18912787c3 356 Gene3D G3DSA:2.40.50.140 62 175 6.5E-23 T 31-10-2018 TK0316 dfed7091b439a2bef9ae8ea6c26e4328 325 Pfam PF05763 Protein of unknown function (DUF835) 182 321 6.2E-34 T 31-10-2018 IPR008553 Domain of unknown function DUF835 TK0316 dfed7091b439a2bef9ae8ea6c26e4328 325 PIRSF PIRSF027923 1 325 1.8E-180 T 31-10-2018 IPR015838 Uncharacterised conserved protein UCP027923, rubrerythrin-type TK0316 dfed7091b439a2bef9ae8ea6c26e4328 325 Gene3D G3DSA:1.20.1260.10 15 163 1.1E-33 T 31-10-2018 IPR012347 Ferritin-like TK0316 dfed7091b439a2bef9ae8ea6c26e4328 325 Pfam PF02915 Rubrerythrin 25 159 3.0E-20 T 31-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 TK0316 dfed7091b439a2bef9ae8ea6c26e4328 325 SUPERFAMILY SSF47240 17 163 3.71E-25 T 31-10-2018 IPR009078 Ferritin-like superfamily TK1301 1a7663163a54f7eac0a245f981ffdd9b 381 PIRSF PIRSF016907 2 381 7.2E-148 T 31-10-2018 IPR011386 Putative ATP-NAD kinase TK1301 1a7663163a54f7eac0a245f981ffdd9b 381 Pfam PF01513 ATP-NAD kinase 5 379 8.4E-47 T 31-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 TK1301 1a7663163a54f7eac0a245f981ffdd9b 381 SUPERFAMILY SSF111331 96 152 5.23E-8 T 31-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily TK1301 1a7663163a54f7eac0a245f981ffdd9b 381 Gene3D G3DSA:3.40.50.10330 110 202 8.3E-6 T 31-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 TK1301 1a7663163a54f7eac0a245f981ffdd9b 381 ProDom PD125086 DNA GP2 END PROTECTOR TERMINAL GP2-LIKE T4 ENDS PROTECTS PROTECTING 264 367 8.0E-5 T 31-10-2018 TK0953 709d5bb68e8d331cfd1b32c424479254 602 SMART SM00670 2 115 2.2E-20 T 31-10-2018 IPR002716 PIN domain TK0953 709d5bb68e8d331cfd1b32c424479254 602 Pfam PF00437 Type II/IV secretion system protein 213 370 4.1E-9 T 31-10-2018 IPR001482 Type II/IV secretion system protein TK0953 709d5bb68e8d331cfd1b32c424479254 602 Gene3D G3DSA:3.40.50.1010 1 127 5.5E-32 T 31-10-2018 TK0953 709d5bb68e8d331cfd1b32c424479254 602 SUPERFAMILY SSF52540 134 438 3.31E-29 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK0953 709d5bb68e8d331cfd1b32c424479254 602 Gene3D G3DSA:3.40.50.300 239 426 3.0E-17 T 31-10-2018 TK0953 709d5bb68e8d331cfd1b32c424479254 602 SUPERFAMILY SSF88723 2 132 8.83E-16 T 31-10-2018 IPR029060 PIN-like domain superfamily TK0953 709d5bb68e8d331cfd1b32c424479254 602 SUPERFAMILY SSF54814 464 520 3.01E-6 T 31-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 TK1933 283fbe680e0b5fe8e6e0040e2056cd62 209 Gene3D G3DSA:3.40.50.150 1 207 2.2E-65 T 31-10-2018 TK1933 283fbe680e0b5fe8e6e0040e2056cd62 209 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 116 122 - T 31-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 TK1933 283fbe680e0b5fe8e6e0040e2056cd62 209 SUPERFAMILY SSF53335 3 202 1.34E-35 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TK1933 283fbe680e0b5fe8e6e0040e2056cd62 209 Pfam PF05175 Methyltransferase small domain 39 128 1.2E-14 T 31-10-2018 IPR007848 Methyltransferase small domain GO:0008168 TK0781 594d92c6a5ac3169bc8c03b1b34f141c 348 Gene3D G3DSA:3.40.630.10 6 336 1.0E-136 T 31-10-2018 TK0781 594d92c6a5ac3169bc8c03b1b34f141c 348 Pfam PF05343 M42 glutamyl aminopeptidase 45 335 4.6E-112 T 31-10-2018 IPR008007 Peptidase M42 TK0781 594d92c6a5ac3169bc8c03b1b34f141c 348 PIRSF PIRSF001123 1 348 2.5E-123 T 31-10-2018 IPR008007 Peptidase M42 TK0781 594d92c6a5ac3169bc8c03b1b34f141c 348 SUPERFAMILY SSF53187 5 345 4.34E-70 T 31-10-2018 TK0781 594d92c6a5ac3169bc8c03b1b34f141c 348 Gene3D G3DSA:2.40.30.40 68 161 1.0E-136 T 31-10-2018 IPR023367 Peptidase M42, domain 2 TK0781 594d92c6a5ac3169bc8c03b1b34f141c 348 SUPERFAMILY SSF101821 68 177 5.8E-31 T 31-10-2018 TK0502 ade292cf83b07fe751652c4e1c9cef4b 455 SUPERFAMILY SSF111283 3 450 1.7E-97 T 31-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 TK0502 ade292cf83b07fe751652c4e1c9cef4b 455 Gene3D G3DSA:3.30.2290.10 2 212 1.2E-16 T 31-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal TK0502 ade292cf83b07fe751652c4e1c9cef4b 455 PIRSF PIRSF004919 1 455 2.2E-160 T 31-10-2018 IPR025502 TldD TK0502 ade292cf83b07fe751652c4e1c9cef4b 455 Pfam PF01523 Putative modulator of DNA gyrase 19 310 6.5E-46 T 31-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 TK0732 e6e80fcc91c92dabbfe670cad2e4b41f 154 SUPERFAMILY SSF53146 1 112 2.22E-30 T 31-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily TK0732 e6e80fcc91c92dabbfe670cad2e4b41f 154 Gene3D G3DSA:3.30.420.130 1 115 1.9E-31 T 31-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily TK0732 e6e80fcc91c92dabbfe670cad2e4b41f 154 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 13 106 1.3E-22 T 31-10-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis TK0125 15cfc249b6e194f9b4d5b2ddcf3233bd 169 Pfam PF00583 Acetyltransferase (GNAT) family 25 144 3.9E-22 T 31-10-2018 IPR000182 GNAT domain TK0125 15cfc249b6e194f9b4d5b2ddcf3233bd 169 Gene3D G3DSA:3.40.630.30 5 162 9.6E-52 T 31-10-2018 TK0125 15cfc249b6e194f9b4d5b2ddcf3233bd 169 SUPERFAMILY SSF55729 8 157 7.26E-31 T 31-10-2018 IPR016181 Acyl-CoA N-acyltransferase TK1725 65f5affa67959a4819fbfdfec3949e70 1242 Gene3D G3DSA:2.60.120.260 872 962 9.2E-6 T 31-10-2018 IPR008979 Galactose-binding-like domain superfamily TK1725 65f5affa67959a4819fbfdfec3949e70 1242 Gene3D G3DSA:2.60.120.260 705 871 3.0E-9 T 31-10-2018 IPR008979 Galactose-binding-like domain superfamily TK1725 65f5affa67959a4819fbfdfec3949e70 1242 SUPERFAMILY SSF49785 742 870 8.79E-5 T 31-10-2018 IPR008979 Galactose-binding-like domain superfamily TK0270 9e1f54df1c2db019e97a1d91f5414361 219 SUPERFAMILY SSF52518 42 216 4.15E-55 T 31-10-2018 IPR029061 Thiamin diphosphate-binding fold TK0270 9e1f54df1c2db019e97a1d91f5414361 219 Gene3D G3DSA:3.40.50.970 7 216 2.9E-62 T 31-10-2018 TK0270 9e1f54df1c2db019e97a1d91f5414361 219 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 42 216 4.2E-28 T 31-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 TK0503 7415caa290856b496f7c2c92ac2285fe 113 SUPERFAMILY SSF51182 10 105 6.31E-24 T 31-10-2018 IPR011051 RmlC-like cupin domain superfamily TK0503 7415caa290856b496f7c2c92ac2285fe 113 Gene3D G3DSA:2.60.120.10 10 108 4.7E-22 T 31-10-2018 IPR014710 RmlC-like jelly roll fold TK0503 7415caa290856b496f7c2c92ac2285fe 113 Pfam PF07883 Cupin domain 32 100 7.1E-19 T 31-10-2018 IPR013096 Cupin 2, conserved barrel TK0874 2530b8effbf6215fa84d85f1d54b932b 191 Gene3D G3DSA:3.60.21.10 14 151 2.5E-7 T 31-10-2018 IPR029052 Metallo-dependent phosphatase-like TK0874 2530b8effbf6215fa84d85f1d54b932b 191 Pfam PF00149 Calcineurin-like phosphoesterase 24 162 1.4E-6 T 31-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 TK0874 2530b8effbf6215fa84d85f1d54b932b 191 SUPERFAMILY SSF56300 23 179 1.22E-20 T 31-10-2018 TK2075 23ad5378d22627684df006eaf94e881e 168 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 80 91 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TK2075 23ad5378d22627684df006eaf94e881e 168 SUPERFAMILY SSF54862 1 149 8.27E-51 T 31-10-2018 TK2075 23ad5378d22627684df006eaf94e881e 168 Gene3D G3DSA:3.30.70.20 33 161 6.1E-40 T 31-10-2018 TK2075 23ad5378d22627684df006eaf94e881e 168 Pfam PF13247 4Fe-4S dicluster domain 44 135 2.8E-27 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TK0952 264ae579f5fe132bdacb3b9cf8e88af9 245 TIGRFAM TIGR01969 minD_arch: cell division ATPase MinD 4 236 3.2E-102 T 31-10-2018 IPR010224 ATP binding protein MinD, archaea TK0952 264ae579f5fe132bdacb3b9cf8e88af9 245 Gene3D G3DSA:3.40.50.300 1 236 1.4E-77 T 31-10-2018 TK0952 264ae579f5fe132bdacb3b9cf8e88af9 245 Pfam PF13614 AAA domain 3 145 8.5E-32 T 31-10-2018 IPR025669 AAA domain TK0952 264ae579f5fe132bdacb3b9cf8e88af9 245 SUPERFAMILY SSF52540 1 235 9.69E-65 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK0952 264ae579f5fe132bdacb3b9cf8e88af9 245 PIRSF PIRSF003092 1 241 8.4E-57 T 31-10-2018 IPR025501 ATP binding protein MinD TK1288 5e386cdf126299222e5c6cefbcef8de7 477 PIRSF PIRSF006603 3 477 6.6E-165 T 31-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 TK1288 5e386cdf126299222e5c6cefbcef8de7 477 TIGRFAM TIGR00797 matE: MATE efflux family protein 28 423 2.2E-70 T 31-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 TK1288 5e386cdf126299222e5c6cefbcef8de7 477 Pfam PF01554 MatE 253 415 5.5E-27 T 31-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 TK1288 5e386cdf126299222e5c6cefbcef8de7 477 Pfam PF01554 MatE 28 188 1.6E-31 T 31-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 TK2152 744b19e0b20a4595f3337486e84e3102 211 Pfam PF04252 Predicted SAM-dependent RNA methyltransferase 4 188 1.4E-47 T 31-10-2018 IPR007364 RNA methyltransferase TK0422/Sfm1 GO:0008168 TK1100 f9c8a5dc3fe4311d8978e774bc4aaa8a 275 Gene3D G3DSA:1.10.150.190 86 171 2.4E-33 T 31-10-2018 IPR024054 Translation initiation factor 2, alpha subunit, middle domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-381042|Reactome: R-HSA-382556|Reactome: R-HSA-72649|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72731 TK1100 f9c8a5dc3fe4311d8978e774bc4aaa8a 275 Gene3D G3DSA:3.30.70.1130 173 262 1.1E-32 T 31-10-2018 IPR024055 Translation initiation factor 2, alpha subunit, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-381042|Reactome: R-HSA-382556|Reactome: R-HSA-72649|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72731 TK1100 f9c8a5dc3fe4311d8978e774bc4aaa8a 275 SUPERFAMILY SSF50249 7 87 3.72E-21 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold TK1100 f9c8a5dc3fe4311d8978e774bc4aaa8a 275 Hamap MF_00231 Translation initiation factor 2 subunit alpha [eif2a]. 3 263 33.956 T 31-10-2018 IPR022964 Translation initiation factor 2, alpha subunit, archaeal TK1100 f9c8a5dc3fe4311d8978e774bc4aaa8a 275 SMART SM00316 10 83 8.2E-25 T 31-10-2018 IPR022967 RNA-binding domain, S1 TK1100 f9c8a5dc3fe4311d8978e774bc4aaa8a 275 SUPERFAMILY SSF116742 85 174 4.32E-24 T 31-10-2018 IPR024054 Translation initiation factor 2, alpha subunit, middle domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-381042|Reactome: R-HSA-382556|Reactome: R-HSA-72649|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72731 TK1100 f9c8a5dc3fe4311d8978e774bc4aaa8a 275 SUPERFAMILY SSF110993 176 260 4.32E-22 T 31-10-2018 IPR024055 Translation initiation factor 2, alpha subunit, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-381042|Reactome: R-HSA-382556|Reactome: R-HSA-72649|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72731 TK1100 f9c8a5dc3fe4311d8978e774bc4aaa8a 275 Gene3D G3DSA:2.40.50.140 3 85 1.4E-31 T 31-10-2018 TK1100 f9c8a5dc3fe4311d8978e774bc4aaa8a 275 Pfam PF07541 Eukaryotic translation initiation factor 2 alpha subunit 122 233 2.7E-23 T 31-10-2018 IPR011488 Translation initiation factor 2, alpha subunit GO:0003723|GO:0003743 Reactome: R-HSA-156827|Reactome: R-HSA-381042|Reactome: R-HSA-382556|Reactome: R-HSA-72649|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72731 TK1100 f9c8a5dc3fe4311d8978e774bc4aaa8a 275 Pfam PF00575 S1 RNA binding domain 9 83 4.5E-13 T 31-10-2018 IPR003029 S1 domain GO:0003676 TK1515 902fc671ab57a4c95a9530f002c89e0e 90 PRINTS PR01250 Ribosomal protein L34 signature 18 35 2.6E-17 T 31-10-2018 IPR008195 Ribosomal protein L34Ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1515 902fc671ab57a4c95a9530f002c89e0e 90 PRINTS PR01250 Ribosomal protein L34 signature 56 78 2.6E-17 T 31-10-2018 IPR008195 Ribosomal protein L34Ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1515 902fc671ab57a4c95a9530f002c89e0e 90 PRINTS PR01250 Ribosomal protein L34 signature 36 46 2.6E-17 T 31-10-2018 IPR008195 Ribosomal protein L34Ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1515 902fc671ab57a4c95a9530f002c89e0e 90 PRINTS PR01250 Ribosomal protein L34 signature 5 18 2.6E-17 T 31-10-2018 IPR008195 Ribosomal protein L34Ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1515 902fc671ab57a4c95a9530f002c89e0e 90 Hamap MF_00349 50S ribosomal protein L34e [rpl34e]. 1 86 29.233 T 31-10-2018 IPR008195 Ribosomal protein L34Ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1515 902fc671ab57a4c95a9530f002c89e0e 90 ProSitePatterns PS01145 Ribosomal protein L34e signature. 7 20 - T 31-10-2018 IPR018065 Ribosomal protein L34e, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1515 902fc671ab57a4c95a9530f002c89e0e 90 Pfam PF01199 Ribosomal protein L34e 3 83 3.2E-24 T 31-10-2018 IPR008195 Ribosomal protein L34Ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1515 902fc671ab57a4c95a9530f002c89e0e 90 Gene3D G3DSA:3.40.1800.40 29 86 9.4E-10 T 31-10-2018 IPR038562 Ribosomal protein L34Ae superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1476 e68129218aa2be4e15a1d2ad01035407 124 SUPERFAMILY SSF81301 3 95 1.23E-16 T 31-10-2018 TK1476 e68129218aa2be4e15a1d2ad01035407 124 Pfam PF01909 Nucleotidyltransferase domain 10 61 1.8E-10 T 31-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 TK1476 e68129218aa2be4e15a1d2ad01035407 124 Gene3D G3DSA:3.30.460.10 2 97 4.3E-14 T 31-10-2018 TK2282 7593bfb5587cfb3ff27e3376a4517c4d 484 Pfam PF09847 Membrane protein of 12 TMs 36 481 3.0E-144 T 31-10-2018 IPR018646 Membrane protein of 12 TMs TK2282 7593bfb5587cfb3ff27e3376a4517c4d 484 PIRSF PIRSF018875 1 482 4.5E-49 T 31-10-2018 IPR018646 Membrane protein of 12 TMs TK0536 4574f3c5ebfbab35df96480ab7acfc4e 188 PIRSF PIRSF019075 1 188 6.4E-86 T 31-10-2018 IPR016745 Uncharacterised conserved protein UCP019075 TK0536 4574f3c5ebfbab35df96480ab7acfc4e 188 Gene3D G3DSA:1.20.58.1030 1 113 1.4E-51 T 31-10-2018 TK0536 4574f3c5ebfbab35df96480ab7acfc4e 188 Gene3D G3DSA:3.40.5.50 129 188 1.9E-37 T 31-10-2018 TK0761 2bec2520c144f7e805524ea05b41378c 306 Pfam PF01384 Phosphate transporter family 16 296 1.5E-52 T 31-10-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 TK1735 e90b6066f1081539a2f2ccf3ee9e4f79 145 Gene3D G3DSA:1.20.1260.10 1 143 1.3E-12 T 31-10-2018 IPR012347 Ferritin-like TK1735 e90b6066f1081539a2f2ccf3ee9e4f79 145 SUPERFAMILY SSF47240 5 143 2.03E-16 T 31-10-2018 IPR009078 Ferritin-like superfamily TK1735 e90b6066f1081539a2f2ccf3ee9e4f79 145 Pfam PF02915 Rubrerythrin 91 144 1.1E-6 T 31-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 TK0014 01d47322e4831dbd2f3a03c059cffc17 185 Pfam PF13023 HD domain 9 147 3.8E-33 T 31-10-2018 IPR006674 HD domain TK0014 01d47322e4831dbd2f3a03c059cffc17 185 Gene3D G3DSA:1.10.3210.10 1 182 3.8E-62 T 31-10-2018 TK0014 01d47322e4831dbd2f3a03c059cffc17 185 SUPERFAMILY SSF109604 2 171 9.2E-44 T 31-10-2018 TK0014 01d47322e4831dbd2f3a03c059cffc17 185 SMART SM00471 26 144 7.5E-14 T 31-10-2018 IPR003607 HD/PDEase domain TK0462 ccc78bb8cd6c6279c6997a945e8d99fc 358 TIGRFAM TIGR02585 cas_Cst2_DevR: CRISPR-associated protein Cas7/Cst2/DevR, subtype I-B/TNEAP 14 348 1.2E-80 T 31-10-2018 IPR013414 CRISPR-associated protein Cas7, subtype I-B/Tneap TK0462 ccc78bb8cd6c6279c6997a945e8d99fc 358 Pfam PF01905 CRISPR-associated negative auto-regulator DevR/Csa2 16 254 6.3E-16 T 31-10-2018 IPR010154 CRISPR-associated protein Cas7/Cst2/DevR TK0462 ccc78bb8cd6c6279c6997a945e8d99fc 358 TIGRFAM TIGR01875 cas_MJ0381: CRISPR-associated autoregulator DevR family 20 262 1.5E-41 T 31-10-2018 IPR010154 CRISPR-associated protein Cas7/Cst2/DevR TK0565 d90e8cc5d4cb213a2593ce724c5e766f 139 Gene3D G3DSA:3.30.1330.80 1 139 1.1E-49 T 31-10-2018 TK0565 d90e8cc5d4cb213a2593ce724c5e766f 139 SUPERFAMILY SSF117856 3 126 3.66E-38 T 31-10-2018 TK0565 d90e8cc5d4cb213a2593ce724c5e766f 139 Pfam PF03479 Domain of unknown function (DUF296) 7 117 3.6E-22 T 31-10-2018 IPR005175 PPC domain TK0565 d90e8cc5d4cb213a2593ce724c5e766f 139 PIRSF PIRSF016702 1 139 9.6E-48 T 31-10-2018 IPR025707 Predicted DNA-binding protein with PD1-like DNA-binding motif TK1924 d0e91352fe73c9a83cf3b78f9059769d 118 SUPERFAMILY SSF46785 15 114 3.45E-23 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TK1924 d0e91352fe73c9a83cf3b78f9059769d 118 Pfam PF03551 Transcriptional regulator PadR-like family 26 99 1.4E-22 T 31-10-2018 IPR005149 Transcription regulator PadR, N-terminal TK1924 d0e91352fe73c9a83cf3b78f9059769d 118 Gene3D G3DSA:1.10.10.10 3 117 3.2E-28 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TK0825 b80e0e00b834949bb223c0f30a35aae2 45 SUPERFAMILY SSF46785 4 44 3.96E-9 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TK0825 b80e0e00b834949bb223c0f30a35aae2 45 Gene3D G3DSA:1.10.10.10 2 45 1.6E-9 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TK0423 de839b896692b50121cc4c4a6da96be2 616 Gene3D G3DSA:2.130.10.120 49 362 9.2E-141 T 31-10-2018 TK0423 de839b896692b50121cc4c4a6da96be2 616 Gene3D G3DSA:3.40.50.1820 2 611 9.2E-141 T 31-10-2018 IPR029058 Alpha/Beta hydrolase fold TK0423 de839b896692b50121cc4c4a6da96be2 616 SUPERFAMILY SSF53474 368 615 1.82E-52 T 31-10-2018 IPR029058 Alpha/Beta hydrolase fold TK0423 de839b896692b50121cc4c4a6da96be2 616 Pfam PF00326 Prolyl oligopeptidase family 415 615 5.6E-57 T 31-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 TK0423 de839b896692b50121cc4c4a6da96be2 616 SUPERFAMILY SSF50993 2 366 1.33E-43 T 31-10-2018 TK0423 de839b896692b50121cc4c4a6da96be2 616 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 421 445 8.7E-55 T 31-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 TK0423 de839b896692b50121cc4c4a6da96be2 616 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 475 495 8.7E-55 T 31-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 TK0423 de839b896692b50121cc4c4a6da96be2 616 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 449 468 8.7E-55 T 31-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 TK0423 de839b896692b50121cc4c4a6da96be2 616 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 549 571 8.7E-55 T 31-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 TK0423 de839b896692b50121cc4c4a6da96be2 616 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 395 413 8.7E-55 T 31-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 TK0423 de839b896692b50121cc4c4a6da96be2 616 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 530 545 8.7E-55 T 31-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 TK0423 de839b896692b50121cc4c4a6da96be2 616 Pfam PF02897 Prolyl oligopeptidase, N-terminal beta-propeller domain 2 352 3.9E-19 T 31-10-2018 IPR023302 Peptidase S9A, N-terminal domain GO:0004252|GO:0070008 TK1605 47023455808f7f37e5168cc87179d2fb 255 Pfam PF00753 Metallo-beta-lactamase superfamily 38 228 9.5E-20 T 31-10-2018 IPR001279 Metallo-beta-lactamase TK1605 47023455808f7f37e5168cc87179d2fb 255 Gene3D G3DSA:3.60.15.10 3 245 2.7E-45 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TK1605 47023455808f7f37e5168cc87179d2fb 255 SMART SM00849 39 228 1.8E-23 T 31-10-2018 IPR001279 Metallo-beta-lactamase TK1605 47023455808f7f37e5168cc87179d2fb 255 SUPERFAMILY SSF56281 33 242 3.41E-35 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TK0689 d420c0c1681bff1126289b7893cade26 153 Pfam PF06695 Putative small multi-drug export protein 17 141 7.5E-30 T 31-10-2018 IPR009577 Putative small multi-drug export TK0743 70f6ff6c340f0d8442a672ce38b23245 264 Pfam PF01889 Membrane protein of unknown function DUF63 7 263 1.5E-78 T 31-10-2018 IPR002749 Protein of unknown function DUF63 TK0726 15a437cb4c8acc4d0358966808245d64 239 PIRSF PIRSF006648 2 238 1.5E-27 T 31-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 TK0726 15a437cb4c8acc4d0358966808245d64 239 Pfam PF01061 ABC-2 type transporter 6 204 9.5E-27 T 31-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 TK2141 b8d522310065b76e171a6613859e33b5 300 SUPERFAMILY SSF54211 1 158 6.98E-13 T 31-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TK2141 b8d522310065b76e171a6613859e33b5 300 Pfam PF00288 GHMP kinases N terminal domain 93 151 2.2E-6 T 31-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 TK2141 b8d522310065b76e171a6613859e33b5 300 PIRSF PIRSF016896 1 296 1.8E-91 T 31-10-2018 IPR012043 Pantoate kinase KEGG: 00770+2.7.1.169|MetaCyc: PWY-6654 TK0720 471c35edacdb248d94d8f0472e4c744d 133 Gene3D G3DSA:3.90.1170.20 2 85 6.5E-17 T 31-10-2018 IPR037128 Quinolinate phosphoribosyl transferase, N-terminal domain superfamily GO:0016763 Reactome: R-HSA-196807 TK0720 471c35edacdb248d94d8f0472e4c744d 133 SUPERFAMILY SSF54675 3 67 1.1E-5 T 31-10-2018 TK0720 471c35edacdb248d94d8f0472e4c744d 133 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 2 67 3.1E-7 T 31-10-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 TK0720 471c35edacdb248d94d8f0472e4c744d 133 Gene3D G3DSA:3.20.20.70 86 98 6.5E-17 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TK1300 69e589bf97954c19641ce675417f8f44 482 SUPERFAMILY SSF81324 399 481 1.57E-16 T 31-10-2018 TK1300 69e589bf97954c19641ce675417f8f44 482 Pfam PF07885 Ion channel 412 481 1.9E-13 T 31-10-2018 IPR013099 Potassium channel domain TK1300 69e589bf97954c19641ce675417f8f44 482 Gene3D G3DSA:1.10.287.70 388 482 2.0E-13 T 31-10-2018 TK1625 e21060b9440c01d865eb6394b6bf5e5b 397 Pfam PF03977 Na+-transporting oxaloacetate decarboxylase beta subunit 20 395 6.5E-157 T 31-10-2018 IPR005661 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit GO:0006814|GO:0016829 KEGG: 00620+4.1.1.3 TK1625 e21060b9440c01d865eb6394b6bf5e5b 397 TIGRFAM TIGR01109 Na_pump_decarbB: sodium ion-translocating decarboxylase, beta subunit 19 391 4.3E-157 T 31-10-2018 IPR005661 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit GO:0006814|GO:0016829 KEGG: 00620+4.1.1.3 TK1625 e21060b9440c01d865eb6394b6bf5e5b 397 PIRSF PIRSF015658 1 397 4.0E-166 T 31-10-2018 IPR005661 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit GO:0006814|GO:0016829 KEGG: 00620+4.1.1.3 TK1716 c3f29780b42f080230e9c92367631e9a 229 Gene3D G3DSA:3.90.550.10 1 224 4.6E-46 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TK1716 c3f29780b42f080230e9c92367631e9a 229 SUPERFAMILY SSF53448 2 222 2.5E-41 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TK1716 c3f29780b42f080230e9c92367631e9a 229 Pfam PF01128 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 4 222 1.8E-34 T 31-10-2018 IPR034683 Cytidylyltransferase IspD/TarI GO:0070567 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 TK1716 c3f29780b42f080230e9c92367631e9a 229 ProSitePatterns PS01295 4-diphosphocytidyl-2C-methyl-D-erythritol synthase signature. 98 105 - T 31-10-2018 IPR018294 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, conserved site GO:0003824|GO:0008299 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 TK0012 f3e9bbc536871506e6891559ed4537eb 185 Gene3D G3DSA:3.40.50.300 1 182 3.6E-38 T 31-10-2018 TK0012 f3e9bbc536871506e6891559ed4537eb 185 SUPERFAMILY SSF52540 2 182 2.14E-36 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK0012 f3e9bbc536871506e6891559ed4537eb 185 Pfam PF01926 50S ribosome-binding GTPase 3 136 8.2E-23 T 31-10-2018 IPR006073 GTP binding domain GO:0005525 TK0012 f3e9bbc536871506e6891559ed4537eb 185 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 2 175 3.2E-20 T 31-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 TK0012 f3e9bbc536871506e6891559ed4537eb 185 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 4 24 4.8E-8 T 31-10-2018 IPR006073 GTP binding domain GO:0005525 TK0012 f3e9bbc536871506e6891559ed4537eb 185 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 88 106 4.8E-8 T 31-10-2018 IPR006073 GTP binding domain GO:0005525 TK1153 0c86e10aa93c7bfe6f94950823da7bec 288 Gene3D G3DSA:3.60.15.10 50 127 1.0E-23 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TK1153 0c86e10aa93c7bfe6f94950823da7bec 288 SUPERFAMILY SSF56281 14 276 4.06E-40 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TK1153 0c86e10aa93c7bfe6f94950823da7bec 288 Gene3D G3DSA:3.40.50.10890 128 170 1.0E-23 T 31-10-2018 TK1482 94f26a7860eec5187af477c97eb20284 267 TIGRFAM TIGR01694 MTAP: methylthioadenosine phosphorylase 4 247 4.0E-96 T 31-10-2018 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112|Reactome: R-HSA-8950505 TK1482 94f26a7860eec5187af477c97eb20284 267 Gene3D G3DSA:3.40.50.1580 1 266 3.1E-101 T 31-10-2018 TK1482 94f26a7860eec5187af477c97eb20284 267 ProSitePatterns PS01240 Purine and other phosphorylases family 2 signature. 48 88 - T 31-10-2018 IPR018099 Purine phosphorylase, family 2, conserved site GO:0016763 TK1482 94f26a7860eec5187af477c97eb20284 267 Pfam PF01048 Phosphorylase superfamily 3 246 1.1E-54 T 31-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 TK1482 94f26a7860eec5187af477c97eb20284 267 Hamap MF_01963 S-methyl-5'-thioadenosine phosphorylase [mtnP]. 2 266 43.527 T 31-10-2018 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112|Reactome: R-HSA-8950505 TK1482 94f26a7860eec5187af477c97eb20284 267 SUPERFAMILY SSF53167 1 264 1.07E-95 T 31-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 TK0675 b8c72a7d42ded8d7975f6b4242de1302 445 Pfam PF04055 Radical SAM superfamily 87 229 1.2E-15 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TK0675 b8c72a7d42ded8d7975f6b4242de1302 445 Pfam PF13353 4Fe-4S single cluster domain 85 194 9.2E-11 T 31-10-2018 TK0675 b8c72a7d42ded8d7975f6b4242de1302 445 Gene3D G3DSA:3.20.20.70 79 433 6.9E-65 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TK0675 b8c72a7d42ded8d7975f6b4242de1302 445 Pfam PF13186 Iron-sulfur cluster-binding domain 327 397 9.2E-5 T 31-10-2018 IPR023885 4Fe4S-binding SPASM domain TK0675 b8c72a7d42ded8d7975f6b4242de1302 445 SUPERFAMILY SSF102114 80 370 1.12E-44 T 31-10-2018 TK0762 7f3851eab11a172264ec4ac54b762f42 350 Pfam PF00535 Glycosyl transferase family 2 41 201 2.3E-35 T 31-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TK0762 7f3851eab11a172264ec4ac54b762f42 350 Gene3D G3DSA:3.90.550.10 27 249 2.7E-46 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TK0762 7f3851eab11a172264ec4ac54b762f42 350 SUPERFAMILY SSF53448 30 286 1.76E-55 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TK1204 fcb5f19356cd2c244c6d28d0597367af 153 PIRSF PIRSF018748 1 153 4.7E-61 T 31-10-2018 IPR019271 Protein of unknown function DUF2284, metal-binding TK1204 fcb5f19356cd2c244c6d28d0597367af 153 Pfam PF10050 Predicted metal-binding protein (DUF2284) 8 138 8.2E-35 T 31-10-2018 IPR019271 Protein of unknown function DUF2284, metal-binding TK2094 427b7dbe534dd4dd6df01f5d01abb3c5 177 Gene3D G3DSA:1.20.1260.10 13 162 7.6E-33 T 31-10-2018 IPR012347 Ferritin-like TK2094 427b7dbe534dd4dd6df01f5d01abb3c5 177 SUPERFAMILY SSF47240 18 162 2.38E-26 T 31-10-2018 IPR009078 Ferritin-like superfamily TK2094 427b7dbe534dd4dd6df01f5d01abb3c5 177 Pfam PF02915 Rubrerythrin 22 157 3.3E-15 T 31-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 TK0021 c13bac8620e8d8db08509cf75da78de4 330 Pfam PF00005 ABC transporter 17 160 6.6E-34 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TK0021 c13bac8620e8d8db08509cf75da78de4 330 SUPERFAMILY SSF50331 236 293 2.82E-8 T 31-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal TK0021 c13bac8620e8d8db08509cf75da78de4 330 ProSitePatterns PS00211 ABC transporters family signature. 132 146 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TK0021 c13bac8620e8d8db08509cf75da78de4 330 Gene3D G3DSA:2.40.50.140 251 268 2.0E-7 T 31-10-2018 TK0021 c13bac8620e8d8db08509cf75da78de4 330 Gene3D G3DSA:3.40.50.300 1 239 6.4E-73 T 31-10-2018 TK0021 c13bac8620e8d8db08509cf75da78de4 330 SMART SM00382 26 272 5.5E-13 T 31-10-2018 IPR003593 AAA+ ATPase domain TK0021 c13bac8620e8d8db08509cf75da78de4 330 SUPERFAMILY SSF52540 3 238 2.4E-79 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK0021 c13bac8620e8d8db08509cf75da78de4 330 Gene3D G3DSA:2.40.50.100 269 294 2.0E-7 T 31-10-2018 TK0654 f67095467481f4d1379054018dd54109 417 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 259 332 1.1E-15 T 31-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal TK0654 f67095467481f4d1379054018dd54109 417 Pfam PF07282 Putative transposase DNA-binding domain 318 370 3.2E-16 T 31-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal TK0036 c4e32c991dc40ab8f683db18c701d512 109 Pfam PF07381 Winged helix DNA-binding domain (DUF1495) 10 98 1.6E-34 T 31-10-2018 IPR010863 Protein of unknown function DUF1495 TK0036 c4e32c991dc40ab8f683db18c701d512 109 SUPERFAMILY SSF46785 18 107 2.36E-9 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TK1202 48bb17b91e01447e0cc55d5be551c13b 326 SUPERFAMILY SSF88723 106 246 7.85E-5 T 31-10-2018 IPR029060 PIN-like domain superfamily TK2283 f110b1cac3e189eb7fbc4207ce8a04e1 118 SUPERFAMILY SSF64076 2 118 6.15E-37 T 31-10-2018 IPR036748 MTH938-like superfamily TK2283 f110b1cac3e189eb7fbc4207ce8a04e1 118 Gene3D G3DSA:3.40.1230.10 1 118 1.2E-36 T 31-10-2018 IPR036748 MTH938-like superfamily TK2283 f110b1cac3e189eb7fbc4207ce8a04e1 118 Pfam PF04430 Protein of unknown function (DUF498/DUF598) 8 114 2.3E-12 T 31-10-2018 IPR007523 NDUFAF3/Mth938 domain-containing protein TK2037 8788df94e7bd8d6de4b6ed98c2dc67aa 164 Pfam PF00717 Peptidase S24-like 38 86 1.6E-6 T 31-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C TK2037 8788df94e7bd8d6de4b6ed98c2dc67aa 164 TIGRFAM TIGR02228 sigpep_I_arch: signal peptidase I 3 155 4.2E-40 T 31-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 TK2037 8788df94e7bd8d6de4b6ed98c2dc67aa 164 SUPERFAMILY SSF51306 35 88 3.14E-10 T 31-10-2018 IPR036286 LexA/Signal peptidase-like superfamily TK2037 8788df94e7bd8d6de4b6ed98c2dc67aa 164 PRINTS PR00728 Eukaryotic signal peptidase (S26B) family signature 101 112 3.9E-9 T 31-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 TK2037 8788df94e7bd8d6de4b6ed98c2dc67aa 164 PRINTS PR00728 Eukaryotic signal peptidase (S26B) family signature 38 53 3.9E-9 T 31-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 TK1206 ef9f36632bc90a9d3e21abeb1ee9f950 83 Gene3D G3DSA:1.20.1280.290 1 83 1.5E-9 T 31-10-2018 TK0673 06b1254d89c9b25f3587a9c67efa2c22 259 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 10 253 2.5E-32 T 31-10-2018 TK0673 06b1254d89c9b25f3587a9c67efa2c22 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 75 86 9.9E-17 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TK0673 06b1254d89c9b25f3587a9c67efa2c22 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 2 19 9.9E-17 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TK0673 06b1254d89c9b25f3587a9c67efa2c22 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 9.9E-17 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TK0673 06b1254d89c9b25f3587a9c67efa2c22 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 9.9E-17 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TK0673 06b1254d89c9b25f3587a9c67efa2c22 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 189 9.9E-17 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TK0673 06b1254d89c9b25f3587a9c67efa2c22 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 217 237 9.9E-17 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TK0673 06b1254d89c9b25f3587a9c67efa2c22 259 Gene3D G3DSA:3.40.50.720 1 258 4.5E-47 T 31-10-2018 TK0673 06b1254d89c9b25f3587a9c67efa2c22 259 SUPERFAMILY SSF51735 2 254 9.42E-50 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily TK1323 3d69ce46566cc0b4669995a5be79430d 384 Pfam PF13439 Glycosyltransferase Family 4 14 182 3.8E-29 T 31-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 TK1323 3d69ce46566cc0b4669995a5be79430d 384 Gene3D G3DSA:3.40.50.2000 1 202 5.8E-42 T 31-10-2018 TK1323 3d69ce46566cc0b4669995a5be79430d 384 Gene3D G3DSA:3.40.50.2000 203 364 6.6E-51 T 31-10-2018 TK1323 3d69ce46566cc0b4669995a5be79430d 384 SUPERFAMILY SSF53756 1 381 5.07E-100 T 31-10-2018 TK1323 3d69ce46566cc0b4669995a5be79430d 384 Pfam PF00534 Glycosyl transferases group 1 202 358 3.1E-48 T 31-10-2018 IPR001296 Glycosyl transferase, family 1 TK1644 65bbc3da7e7a6bd3c81cde34fb026035 148 Gene3D G3DSA:3.40.50.1010 1 146 3.5E-13 T 31-10-2018 TK1644 65bbc3da7e7a6bd3c81cde34fb026035 148 SMART SM00670 1 139 2.0E-6 T 31-10-2018 IPR002716 PIN domain TK1644 65bbc3da7e7a6bd3c81cde34fb026035 148 Pfam PF01850 PIN domain 2 142 1.8E-25 T 31-10-2018 IPR002716 PIN domain TK1644 65bbc3da7e7a6bd3c81cde34fb026035 148 SUPERFAMILY SSF88723 2 142 8.69E-19 T 31-10-2018 IPR029060 PIN-like domain superfamily TK1644 65bbc3da7e7a6bd3c81cde34fb026035 148 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 2 147 9.442 T 31-10-2018 IPR022907 VapC family GO:0004540 TK1597 ba476b47815fc6828787e0224b831c9a 663 Gene3D G3DSA:1.20.1460.20 47 290 2.3E-26 T 31-10-2018 TK1597 ba476b47815fc6828787e0224b831c9a 663 Gene3D G3DSA:3.30.70.2750 149 224 2.3E-26 T 31-10-2018 TK1597 ba476b47815fc6828787e0224b831c9a 663 Gene3D G3DSA:3.30.70.2170 7 309 2.3E-26 T 31-10-2018 TK1597 ba476b47815fc6828787e0224b831c9a 663 Pfam PF01496 V-type ATPase 116kDa subunit family 558 651 4.9E-12 T 31-10-2018 IPR002490 V-type ATPase, V0 complex, 116kDa subunit family GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TK1597 ba476b47815fc6828787e0224b831c9a 663 Pfam PF01496 V-type ATPase 116kDa subunit family 190 440 1.9E-23 T 31-10-2018 IPR002490 V-type ATPase, V0 complex, 116kDa subunit family GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TK1824 74ed373019db76126467817b5ae2930a 247 Gene3D G3DSA:3.40.50.300 3 247 4.7E-68 T 31-10-2018 TK0374 a47b4cb841b178aca5def246de32577a 138 Pfam PF01850 PIN domain 2 128 6.3E-10 T 31-10-2018 IPR002716 PIN domain TK0374 a47b4cb841b178aca5def246de32577a 138 Gene3D G3DSA:3.40.50.1010 1 130 2.7E-29 T 31-10-2018 TK0374 a47b4cb841b178aca5def246de32577a 138 SUPERFAMILY SSF88723 2 135 6.17E-18 T 31-10-2018 IPR029060 PIN-like domain superfamily TK0887 3564c0bf4036fc1804a893cb51343b9a 421 Gene3D G3DSA:3.20.20.140 2 234 1.2E-16 T 31-10-2018 TK0887 3564c0bf4036fc1804a893cb51343b9a 421 Pfam PF13263 PHP-associated 175 225 1.5E-4 T 31-10-2018 TK0887 3564c0bf4036fc1804a893cb51343b9a 421 SUPERFAMILY SSF89550 5 229 4.71E-16 T 31-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 TK0887 3564c0bf4036fc1804a893cb51343b9a 421 TIGRFAM TIGR00375 TIGR00375: TIGR00375 family protein 5 379 1.7E-130 T 31-10-2018 IPR005287 Conserved hypothetical protein CHP00375 TK0549 c9691f057fcc78a7b53beae4f2199a3d 536 Gene3D G3DSA:3.30.420.40 9 312 2.0E-66 T 31-10-2018 TK0549 c9691f057fcc78a7b53beae4f2199a3d 536 Gene3D G3DSA:3.30.420.350 95 305 2.0E-66 T 31-10-2018 TK0549 c9691f057fcc78a7b53beae4f2199a3d 536 Pfam PF16861 Carbamoyltransferase C-terminus 366 536 8.7E-63 T 31-10-2018 IPR031730 Carbamoyltransferase, C-terminal TK0549 c9691f057fcc78a7b53beae4f2199a3d 536 SUPERFAMILY SSF53067 11 315 1.15E-12 T 31-10-2018 TK0549 c9691f057fcc78a7b53beae4f2199a3d 536 Gene3D G3DSA:3.90.870.20 330 535 1.5E-75 T 31-10-2018 IPR038152 Carbamoyltransferase, C-terminal domain superfamily TK0549 c9691f057fcc78a7b53beae4f2199a3d 536 Pfam PF02543 Carbamoyltransferase N-terminus 85 312 2.0E-38 T 31-10-2018 IPR003696 Carbamoyltransferase GO:0003824|GO:0009058 TK0549 c9691f057fcc78a7b53beae4f2199a3d 536 Pfam PF02543 Carbamoyltransferase N-terminus 2 65 1.5E-9 T 31-10-2018 IPR003696 Carbamoyltransferase GO:0003824|GO:0009058 TK0255 561ff4658fda7a39887cd60259302a07 192 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 42 56 1.2E-10 T 31-10-2018 TK0255 561ff4658fda7a39887cd60259302a07 192 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 73 89 1.2E-10 T 31-10-2018 TK0255 561ff4658fda7a39887cd60259302a07 192 Pfam PF00117 Glutamine amidotransferase class-I 4 174 6.6E-44 T 31-10-2018 IPR017926 Glutamine amidotransferase TK0255 561ff4658fda7a39887cd60259302a07 192 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 1 187 6.8E-46 T 31-10-2018 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 TK0255 561ff4658fda7a39887cd60259302a07 192 PRINTS PR00097 Anthranilate synthase component II signature 45 54 8.4E-30 T 31-10-2018 TK0255 561ff4658fda7a39887cd60259302a07 192 PRINTS PR00097 Anthranilate synthase component II signature 97 105 8.4E-30 T 31-10-2018 TK0255 561ff4658fda7a39887cd60259302a07 192 PRINTS PR00097 Anthranilate synthase component II signature 73 84 8.4E-30 T 31-10-2018 TK0255 561ff4658fda7a39887cd60259302a07 192 PRINTS PR00097 Anthranilate synthase component II signature 117 129 8.4E-30 T 31-10-2018 TK0255 561ff4658fda7a39887cd60259302a07 192 PRINTS PR00097 Anthranilate synthase component II signature 161 174 8.4E-30 T 31-10-2018 TK0255 561ff4658fda7a39887cd60259302a07 192 PRINTS PR00097 Anthranilate synthase component II signature 2 16 8.4E-30 T 31-10-2018 TK0255 561ff4658fda7a39887cd60259302a07 192 SUPERFAMILY SSF52317 1 188 2.02E-47 T 31-10-2018 IPR029062 Class I glutamine amidotransferase-like TK0255 561ff4658fda7a39887cd60259302a07 192 PRINTS PR00096 Glutamine amidotransferase superfamily signature 45 54 2.0E-13 T 31-10-2018 TK0255 561ff4658fda7a39887cd60259302a07 192 PRINTS PR00096 Glutamine amidotransferase superfamily signature 161 174 2.0E-13 T 31-10-2018 TK0255 561ff4658fda7a39887cd60259302a07 192 PRINTS PR00096 Glutamine amidotransferase superfamily signature 73 84 2.0E-13 T 31-10-2018 TK0255 561ff4658fda7a39887cd60259302a07 192 Gene3D G3DSA:3.40.50.880 1 191 2.5E-51 T 31-10-2018 IPR029062 Class I glutamine amidotransferase-like TK2100 7a97c32cc30777cb118af865dff406b7 330 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 154 174 - T 31-10-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 TK2100 7a97c32cc30777cb118af865dff406b7 330 Gene3D G3DSA:3.50.50.60 18 315 9.4E-116 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TK2100 7a97c32cc30777cb118af865dff406b7 330 SUPERFAMILY SSF51905 15 321 1.84E-62 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TK2100 7a97c32cc30777cb118af865dff406b7 330 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 20 39 4.5E-41 T 31-10-2018 TK2100 7a97c32cc30777cb118af865dff406b7 330 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 249 265 4.5E-41 T 31-10-2018 TK2100 7a97c32cc30777cb118af865dff406b7 330 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 166 184 4.5E-41 T 31-10-2018 TK2100 7a97c32cc30777cb118af865dff406b7 330 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 275 297 4.5E-41 T 31-10-2018 TK2100 7a97c32cc30777cb118af865dff406b7 330 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 124 142 4.5E-41 T 31-10-2018 TK2100 7a97c32cc30777cb118af865dff406b7 330 Gene3D G3DSA:3.50.50.60 136 257 9.4E-116 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TK2100 7a97c32cc30777cb118af865dff406b7 330 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 18 321 3.6E-121 T 31-10-2018 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00450+1.8.1.9 TK2100 7a97c32cc30777cb118af865dff406b7 330 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 19 310 1.4E-61 T 31-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TK2100 7a97c32cc30777cb118af865dff406b7 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 147 159 2.5E-65 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TK2100 7a97c32cc30777cb118af865dff406b7 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 125 133 2.5E-65 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TK2100 7a97c32cc30777cb118af865dff406b7 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 285 303 2.5E-65 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TK2100 7a97c32cc30777cb118af865dff406b7 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 19 41 2.5E-65 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TK2100 7a97c32cc30777cb118af865dff406b7 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 51 66 2.5E-65 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TK2100 7a97c32cc30777cb118af865dff406b7 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 213 229 2.5E-65 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TK2100 7a97c32cc30777cb118af865dff406b7 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 72 82 2.5E-65 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TK2100 7a97c32cc30777cb118af865dff406b7 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 162 186 2.5E-65 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TK2100 7a97c32cc30777cb118af865dff406b7 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 251 272 2.5E-65 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TK0417 062470a46273cba4720d312c72bd2b96 86 SUPERFAMILY SSF103473 4 60 1.01E-5 T 31-10-2018 IPR036259 MFS transporter superfamily TK0473 df0d430c0fbc84e46c6f8e3119143e3f 111 Pfam PF06677 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) 16 48 1.6E-13 T 31-10-2018 IPR009563 Sjoegren syndrome/scleroderma autoantigen 1 TK0473 df0d430c0fbc84e46c6f8e3119143e3f 111 SMART SM00661 26 76 0.0029 T 31-10-2018 IPR001529 DNA-directed RNA polymerase, M/15kDa subunit GO:0006351 TK1336 bdbd55b8538db6bbb83de17a6112e7be 423 Gene3D G3DSA:3.40.1710.10 41 202 1.4E-37 T 31-10-2018 TK1336 bdbd55b8538db6bbb83de17a6112e7be 423 Pfam PF12698 ABC-2 family transporter protein 19 403 2.8E-34 T 31-10-2018 TK0394 2c22bfb567fb7d5c6045153781537873 487 Gene3D G3DSA:3.40.50.300 17 119 4.3E-6 T 31-10-2018 TK0394 2c22bfb567fb7d5c6045153781537873 487 Pfam PF01935 Domain of unknown function DUF87 26 333 4.6E-10 T 31-10-2018 IPR002789 Helicase HerA, central domain TK0394 2c22bfb567fb7d5c6045153781537873 487 Gene3D G3DSA:3.40.50.300 296 485 1.6E-8 T 31-10-2018 TK0394 2c22bfb567fb7d5c6045153781537873 487 SUPERFAMILY SSF52540 19 435 3.83E-16 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK2138 ed022f4372861830e3dee12e57925d20 185 Pfam PF00156 Phosphoribosyl transferase domain 38 159 3.9E-22 T 31-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 TK2138 ed022f4372861830e3dee12e57925d20 185 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 185 27.512 T 31-10-2018 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TK2138 ed022f4372861830e3dee12e57925d20 185 TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase 14 174 8.7E-52 T 31-10-2018 IPR004467 Orotate phosphoribosyl transferase domain GO:0004588 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TK2138 ed022f4372861830e3dee12e57925d20 185 Gene3D G3DSA:3.40.50.2020 1 180 2.2E-58 T 31-10-2018 TK2138 ed022f4372861830e3dee12e57925d20 185 SUPERFAMILY SSF53271 6 171 9.18E-45 T 31-10-2018 IPR029057 Phosphoribosyltransferase-like TK2125 9024bb31758c16c19b5dece9ef55b9c2 254 Pfam PF05763 Protein of unknown function (DUF835) 122 251 2.3E-36 T 31-10-2018 IPR008553 Domain of unknown function DUF835 TK0254 c279c94d777052da452890c72410136a 433 TIGRFAM TIGR01820 TrpE-arch: anthranilate synthase component I 11 430 1.2E-169 T 31-10-2018 IPR010116 Anthranilate synthase component I, archaeal type GO:0000162|GO:0004049 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 TK0254 c279c94d777052da452890c72410136a 433 SUPERFAMILY SSF56322 9 430 1.07E-125 T 31-10-2018 IPR005801 ADC synthase GO:0009058 TK0254 c279c94d777052da452890c72410136a 433 PRINTS PR00095 Anthranilate synthase component I signature 269 282 2.1E-20 T 31-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 TK0254 c279c94d777052da452890c72410136a 433 PRINTS PR00095 Anthranilate synthase component I signature 283 296 2.1E-20 T 31-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 TK0254 c279c94d777052da452890c72410136a 433 PRINTS PR00095 Anthranilate synthase component I signature 363 377 2.1E-20 T 31-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 TK0254 c279c94d777052da452890c72410136a 433 PRINTS PR00095 Anthranilate synthase component I signature 378 392 2.1E-20 T 31-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 TK0254 c279c94d777052da452890c72410136a 433 Gene3D G3DSA:3.60.120.10 4 433 1.5E-138 T 31-10-2018 IPR005801 ADC synthase GO:0009058 TK0254 c279c94d777052da452890c72410136a 433 Pfam PF04715 Anthranilate synthase component I, N terminal region 10 128 2.1E-14 T 31-10-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 TK0254 c279c94d777052da452890c72410136a 433 Pfam PF00425 chorismate binding enzyme 170 421 3.7E-91 T 31-10-2018 IPR015890 Chorismate-utilising enzyme, C-terminal TK0047 ea4d99e6613f72a862e0b05c6e6c7770 232 SUPERFAMILY SSF52540 4 221 1.54E-25 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK0047 ea4d99e6613f72a862e0b05c6e6c7770 232 Gene3D G3DSA:3.40.50.300 3 232 1.5E-43 T 31-10-2018 TK0047 ea4d99e6613f72a862e0b05c6e6c7770 232 Pfam PF06745 KaiC 15 225 8.6E-18 T 31-10-2018 IPR014774 KaiC-like domain TK1257 0d10cb23c6b44eca6d16e18d65786092 355 SMART SM00981 60 149 3.6E-23 T 31-10-2018 IPR004114 THUMP domain GO:0003723 TK1257 0d10cb23c6b44eca6d16e18d65786092 355 Gene3D G3DSA:3.30.2130.30 1 150 5.6E-24 T 31-10-2018 TK1257 0d10cb23c6b44eca6d16e18d65786092 355 SUPERFAMILY SSF75217 189 336 4.34E-21 T 31-10-2018 IPR029028 Alpha/beta knot methyltransferases TK1257 0d10cb23c6b44eca6d16e18d65786092 355 Pfam PF14419 AF2226-like SPOUT RNA Methylase fused to THUMP 169 342 6.2E-84 T 31-10-2018 IPR025849 AF2226-like SPOUT RNA methylase fused to THUMP TK1257 0d10cb23c6b44eca6d16e18d65786092 355 Pfam PF02926 THUMP domain 33 148 1.2E-29 T 31-10-2018 IPR004114 THUMP domain GO:0003723 TK1257 0d10cb23c6b44eca6d16e18d65786092 355 SUPERFAMILY SSF143437 7 147 4.88E-27 T 31-10-2018 TK2150 e883ed687d74f538eeae52737e6754c9 223 TIGRFAM TIGR00659 TIGR00659: TIGR00659 family protein 6 222 6.7E-80 T 31-10-2018 IPR005261 Conserved hypothetical protein CHP00659 TK2150 e883ed687d74f538eeae52737e6754c9 223 Pfam PF04172 LrgB-like family 9 221 5.8E-74 T 31-10-2018 IPR007300 CidB/LrgB family TK2008 9b1d5130e40836d863d03cd2ba4c69c3 139 PIRSF PIRSF004761 1 137 1.6E-36 T 31-10-2018 IPR000688 Hydrogenase maturation factor HypA/HybF GO:0016151|GO:0051604 TK2008 9b1d5130e40836d863d03cd2ba4c69c3 139 Pfam PF01155 Hydrogenase/urease nickel incorporation, metallochaperone, hypA 1 132 4.6E-29 T 31-10-2018 IPR000688 Hydrogenase maturation factor HypA/HybF GO:0016151|GO:0051604 TK2008 9b1d5130e40836d863d03cd2ba4c69c3 139 Gene3D G3DSA:3.30.2320.50 1 83 2.9E-30 T 31-10-2018 TK2008 9b1d5130e40836d863d03cd2ba4c69c3 139 ProSitePatterns PS01249 Hydrogenases expression/synthesis hypA family signature. 34 76 - T 31-10-2018 IPR020538 Hydrogenase nickel incorporation protein HypA/HybF, conserved site TK2008 9b1d5130e40836d863d03cd2ba4c69c3 139 Hamap MF_00213 Hydrogenase maturation factor HypA [hypA]. 1 134 22.156 T 31-10-2018 IPR000688 Hydrogenase maturation factor HypA/HybF GO:0016151|GO:0051604 TK0571 4f42cc82e27f2445b75a824b91e5b454 615 Gene3D G3DSA:1.10.3720.10 336 610 7.4E-39 T 31-10-2018 IPR035906 MetI-like superfamily TK0571 4f42cc82e27f2445b75a824b91e5b454 615 Gene3D G3DSA:1.10.3720.10 67 317 1.3E-52 T 31-10-2018 IPR035906 MetI-like superfamily TK0571 4f42cc82e27f2445b75a824b91e5b454 615 SUPERFAMILY SSF161098 333 608 2.8E-43 T 31-10-2018 IPR035906 MetI-like superfamily TK0571 4f42cc82e27f2445b75a824b91e5b454 615 SUPERFAMILY SSF161098 24 313 1.68E-43 T 31-10-2018 IPR035906 MetI-like superfamily TK0571 4f42cc82e27f2445b75a824b91e5b454 615 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 410 600 2.2E-12 T 31-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TK0571 4f42cc82e27f2445b75a824b91e5b454 615 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 117 311 1.2E-13 T 31-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TK0188 46858cb4f50dc40b725edcb388eff3f9 279 SUPERFAMILY SSF102114 14 219 1.83E-15 T 31-10-2018 TK0188 46858cb4f50dc40b725edcb388eff3f9 279 Gene3D G3DSA:3.80.30.30 51 256 1.9E-13 T 31-10-2018 TK0188 46858cb4f50dc40b725edcb388eff3f9 279 Pfam PF04055 Radical SAM superfamily 23 187 1.4E-16 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TK0188 46858cb4f50dc40b725edcb388eff3f9 279 SMART SM00729 18 228 4.1E-13 T 31-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TK0273 f398c2f490cf2788ecea554254559076 153 Gene3D G3DSA:1.10.3730.10 46 147 2.0E-35 T 31-10-2018 TK0273 f398c2f490cf2788ecea554254559076 153 SUPERFAMILY SSF48179 42 148 1.63E-33 T 31-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 TK0273 f398c2f490cf2788ecea554254559076 153 Gene3D G3DSA:3.40.50.720 1 45 5.9E-8 T 31-10-2018 TK0273 f398c2f490cf2788ecea554254559076 153 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 43 145 1.3E-35 T 31-10-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 TK0273 f398c2f490cf2788ecea554254559076 153 ProSitePatterns PS00521 Delta 1-pyrroline-5-carboxylate reductase signature. 103 125 - T 31-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 TK2237 8d36305dbf3466c587d71eb0e5cc0a25 188 ProDom PD022700 PH0223 5/5 GENOME PF0133 SEGMENT UNCHARACTERIZED MA4198 MJ0805 4 186 3.0E-102 T 31-10-2018 IPR007162 Protein of unknown function DUF366 TK2237 8d36305dbf3466c587d71eb0e5cc0a25 188 PIRSF PIRSF006503 1 188 1.9E-84 T 31-10-2018 IPR007162 Protein of unknown function DUF366 TK2237 8d36305dbf3466c587d71eb0e5cc0a25 188 SUPERFAMILY SSF55681 3 186 4.97E-72 T 31-10-2018 TK2237 8d36305dbf3466c587d71eb0e5cc0a25 188 Pfam PF04017 Domain of unknown function (DUF366) 5 185 3.1E-70 T 31-10-2018 IPR007162 Protein of unknown function DUF366 TK2237 8d36305dbf3466c587d71eb0e5cc0a25 188 Gene3D G3DSA:3.30.930.10 1 188 1.6E-72 T 31-10-2018 TK1296 9b178931fc221d937fae5d9d3a831767 99 Pfam PF04242 Protein of unknown function (DUF424) 7 97 4.9E-33 T 31-10-2018 IPR007355 Protein of unknown function DUF424 TK1296 9b178931fc221d937fae5d9d3a831767 99 Gene3D G3DSA:3.30.1860.10 1 97 2.0E-35 T 31-10-2018 TK0950 9043c133e71545220678f79082c2588c 483 SUPERFAMILY SSF56235 7 212 2.92E-42 T 31-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TK0950 9043c133e71545220678f79082c2588c 483 Pfam PF13537 Glutamine amidotransferase domain 61 179 1.2E-25 T 31-10-2018 IPR017932 Glutamine amidotransferase type 2 domain TK0950 9043c133e71545220678f79082c2588c 483 SUPERFAMILY SSF52402 230 462 6.84E-58 T 31-10-2018 TK0950 9043c133e71545220678f79082c2588c 483 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 364 7.6E-86 T 31-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 TK0950 9043c133e71545220678f79082c2588c 483 PIRSF PIRSF001589 364 483 7.7E-18 T 31-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 TK0950 9043c133e71545220678f79082c2588c 483 PIRSF PIRSF001589 1 370 9.4E-62 T 31-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 TK0950 9043c133e71545220678f79082c2588c 483 Gene3D G3DSA:3.60.20.10 2 221 2.8E-50 T 31-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TK0950 9043c133e71545220678f79082c2588c 483 Gene3D G3DSA:3.40.50.620 222 481 6.7E-76 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TK0950 9043c133e71545220678f79082c2588c 483 Pfam PF00733 Asparagine synthase 230 363 1.7E-35 T 31-10-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 TK0950 9043c133e71545220678f79082c2588c 483 Pfam PF00733 Asparagine synthase 370 462 1.7E-17 T 31-10-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 TK0821 5949cf69451a5dab33dd6b54b7291ee6 263 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 79 253 5.6E-12 T 31-10-2018 TK0821 5949cf69451a5dab33dd6b54b7291ee6 263 SUPERFAMILY SSF49899 59 256 9.93E-24 T 31-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily TK0821 5949cf69451a5dab33dd6b54b7291ee6 263 Gene3D G3DSA:2.60.120.200 73 254 4.9E-15 T 31-10-2018 TK0889 ddb19b744e58d3afef0d92e03e537b7e 141 Gene3D G3DSA:3.40.50.1010 1 116 2.4E-5 T 31-10-2018 TK0889 ddb19b744e58d3afef0d92e03e537b7e 141 SUPERFAMILY SSF88723 1 111 1.32E-15 T 31-10-2018 IPR029060 PIN-like domain superfamily TK0889 ddb19b744e58d3afef0d92e03e537b7e 141 TIGRFAM TIGR00305 TIGR00305: putative toxin-antitoxin system toxin component, PIN family 2 112 6.9E-16 T 31-10-2018 IPR002850 PIN family, putative toxin-antitoxin system toxin component TK0889 ddb19b744e58d3afef0d92e03e537b7e 141 Pfam PF13470 PIN domain 2 107 4.5E-12 T 31-10-2018 IPR002716 PIN domain TK0087 0fccefe4222e14908506646ea9913a2d 435 Gene3D G3DSA:3.40.50.300 35 226 3.6E-5 T 31-10-2018 TK0087 0fccefe4222e14908506646ea9913a2d 435 SUPERFAMILY SSF52540 37 404 6.62E-17 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK0972 fd25bb3c919538df923268dc56bbdd7f 133 SUPERFAMILY SSF88723 2 131 1.12E-15 T 31-10-2018 IPR029060 PIN-like domain superfamily TK0972 fd25bb3c919538df923268dc56bbdd7f 133 Gene3D G3DSA:3.40.50.1010 1 128 9.9E-25 T 31-10-2018 TK0972 fd25bb3c919538df923268dc56bbdd7f 133 Pfam PF01850 PIN domain 2 124 2.2E-10 T 31-10-2018 IPR002716 PIN domain TK2190 979aafc10a37d29d3b6f8a5fc8e6226c 102 Gene3D G3DSA:1.10.10.10 18 80 5.3E-16 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TK2190 979aafc10a37d29d3b6f8a5fc8e6226c 102 SUPERFAMILY SSF46785 20 98 5.88E-16 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TK2190 979aafc10a37d29d3b6f8a5fc8e6226c 102 Pfam PF01022 Bacterial regulatory protein, arsR family 20 64 5.7E-10 T 31-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TK0933 6172ba087ecedeed4103a00cce7acbd3 71 SUPERFAMILY SSF50182 6 71 8.17E-32 T 31-10-2018 IPR010920 LSM domain superfamily TK0933 6172ba087ecedeed4103a00cce7acbd3 71 Gene3D G3DSA:2.30.30.100 2 71 1.3E-29 T 31-10-2018 TK1693 e67ebe8e3f9da8c544ed9de1ef86d117 177 SUPERFAMILY SSF117916 78 175 2.26E-32 T 31-10-2018 IPR034904 Fe-S cluster assembly domain superfamily TK1693 e67ebe8e3f9da8c544ed9de1ef86d117 177 Pfam PF01883 Iron-sulfur cluster assembly protein 81 154 3.7E-21 T 31-10-2018 IPR002744 MIP18 family-like TK1693 e67ebe8e3f9da8c544ed9de1ef86d117 177 Gene3D G3DSA:3.30.300.130 72 176 4.1E-36 T 31-10-2018 IPR034904 Fe-S cluster assembly domain superfamily TK0046 af3c340b0564450edd2d8485102731ac 161 Pfam PF01917 Archaebacterial flagellin 5 156 4.4E-24 T 31-10-2018 IPR002774 Flagellin, archaea GO:0005198|GO:0006928 TK1374 e686d05ab7f389eb10b9280bf7b14e99 108 Gene3D G3DSA:1.20.5.340 28 105 1.4E-5 T 31-10-2018 TK2285 7dbff730e982ffc87fc994117511c4b1 273 SUPERFAMILY SSF53613 1 263 4.99E-31 T 31-10-2018 IPR029056 Ribokinase-like TK2285 7dbff730e982ffc87fc994117511c4b1 273 Gene3D G3DSA:3.40.1190.20 1 273 1.5E-110 T 31-10-2018 IPR029056 Ribokinase-like TK1341 a57e4bbee6d8161e0a6a9c831538c067 127 Pfam PF09946 Predicted membrane protein (DUF2178) 11 112 1.7E-13 T 31-10-2018 IPR019235 Protein of unknown function DUF2178, transmembrane TK0288 c452fb1fa54f7035d02ef1a995a9b5c3 249 SMART SM00849 37 215 1.7E-12 T 31-10-2018 IPR001279 Metallo-beta-lactamase TK0288 c452fb1fa54f7035d02ef1a995a9b5c3 249 Gene3D G3DSA:3.60.15.10 1 249 1.0E-48 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TK0288 c452fb1fa54f7035d02ef1a995a9b5c3 249 Pfam PF12706 Beta-lactamase superfamily domain 50 216 7.2E-18 T 31-10-2018 IPR001279 Metallo-beta-lactamase TK0288 c452fb1fa54f7035d02ef1a995a9b5c3 249 SUPERFAMILY SSF56281 1 247 1.06E-39 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TK0902 d066ef24a73b2bbe708c5825ff6fb1c2 98 Gene3D G3DSA:2.30.30.70 2 97 1.0E-36 T 31-10-2018 IPR036948 Ribosomal protein L21 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK0902 d066ef24a73b2bbe708c5825ff6fb1c2 98 Pfam PF01157 Ribosomal protein L21e 6 96 1.1E-32 T 31-10-2018 IPR001147 Ribosomal protein L21e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK0902 d066ef24a73b2bbe708c5825ff6fb1c2 98 SUPERFAMILY SSF50104 6 97 7.22E-32 T 31-10-2018 IPR008991 Translation protein SH3-like domain superfamily TK0902 d066ef24a73b2bbe708c5825ff6fb1c2 98 ProSitePatterns PS01171 Ribosomal protein L21e signature. 38 63 - T 31-10-2018 IPR018259 Ribosomal protein L21e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK0902 d066ef24a73b2bbe708c5825ff6fb1c2 98 Hamap MF_00369 50S ribosomal protein L21e [rpl21e]. 3 97 30.414 T 31-10-2018 IPR022856 Ribosomal protein L21e, archaeal TK1598 5015cf3e0f2819c15f921ffd3e21e251 161 Gene3D G3DSA:1.20.120.610 1 157 3.0E-40 T 31-10-2018 TK1598 5015cf3e0f2819c15f921ffd3e21e251 161 SUPERFAMILY SSF81333 6 70 2.09E-11 T 31-10-2018 IPR035921 F/V-ATP synthase subunit C superfamily TK1598 5015cf3e0f2819c15f921ffd3e21e251 161 Pfam PF00137 ATP synthase subunit C 9 68 7.1E-14 T 31-10-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 TK1598 5015cf3e0f2819c15f921ffd3e21e251 161 Pfam PF00137 ATP synthase subunit C 96 154 9.8E-16 T 31-10-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 TK1598 5015cf3e0f2819c15f921ffd3e21e251 161 SUPERFAMILY SSF81333 88 155 2.09E-13 T 31-10-2018 IPR035921 F/V-ATP synthase subunit C superfamily TK0601 f0b35a161b8fb2f95d0721ce7626d36a 433 SMART SM00382 24 386 2.1E-4 T 31-10-2018 IPR003593 AAA+ ATPase domain TK0601 f0b35a161b8fb2f95d0721ce7626d36a 433 Gene3D G3DSA:3.40.50.300 239 376 1.4E-7 T 31-10-2018 TK0601 f0b35a161b8fb2f95d0721ce7626d36a 433 SUPERFAMILY SSF52540 3 376 1.09E-16 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK0601 f0b35a161b8fb2f95d0721ce7626d36a 433 Gene3D G3DSA:3.40.50.300 5 90 8.0E-7 T 31-10-2018 TK0454 d25b8750ea20b460ec5a824c90eb3ed5 121 Gene3D G3DSA:1.20.120.1610 1 79 1.8E-24 T 31-10-2018 TK0454 d25b8750ea20b460ec5a824c90eb3ed5 121 TIGRFAM TIGR01878 cas_Csa5: CRISPR type I-A/APERN-associated protein Csa5 18 113 9.6E-31 T 31-10-2018 IPR010157 CRISPR type I-A/APERN-associated protein Csa5 TK0454 d25b8750ea20b460ec5a824c90eb3ed5 121 Pfam PF09702 CRISPR-associated protein (Cas_Csa5) 19 113 3.4E-29 T 31-10-2018 IPR010157 CRISPR type I-A/APERN-associated protein Csa5 TK1504 359b2d12159d43136ea13885e7e6aaaf 140 PIRSF PIRSF002131 1 139 6.2E-37 T 31-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 TK1504 359b2d12159d43136ea13885e7e6aaaf 140 TIGRFAM TIGR03628 arch_S11P: ribosomal protein uS11 16 132 1.1E-67 T 31-10-2018 IPR019961 Ribosomal protein S11, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 TK1504 359b2d12159d43136ea13885e7e6aaaf 140 Gene3D G3DSA:3.30.420.80 4 140 2.5E-66 T 31-10-2018 IPR036967 Ribosomal protein S11 superfamily GO:0003735|GO:0005840|GO:0006412 TK1504 359b2d12159d43136ea13885e7e6aaaf 140 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 12 137 24.005 T 31-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 TK1504 359b2d12159d43136ea13885e7e6aaaf 140 SUPERFAMILY SSF53137 12 138 3.79E-40 T 31-10-2018 TK1504 359b2d12159d43136ea13885e7e6aaaf 140 ProSitePatterns PS00054 Ribosomal protein S11 signature. 105 127 - T 31-10-2018 IPR018102 Ribosomal S11, conserved site TK1504 359b2d12159d43136ea13885e7e6aaaf 140 Pfam PF00411 Ribosomal protein S11 18 136 3.6E-48 T 31-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 TK0618 5ebf98e01835ba27c183807cdf2eb450 201 PIRSF PIRSF019239 29 201 6.2E-62 T 31-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 TK0618 5ebf98e01835ba27c183807cdf2eb450 201 Pfam PF01899 Na+/H+ ion antiporter subunit 40 199 4.7E-41 T 31-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 TK1927 88d5aa57f30cd03d6c7636dcaa57cb32 204 Pfam PF05708 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family 44 200 7.0E-41 T 31-10-2018 IPR024453 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family TK1927 88d5aa57f30cd03d6c7636dcaa57cb32 204 Gene3D G3DSA:3.90.1720.10 44 199 9.5E-16 T 31-10-2018 TK1927 88d5aa57f30cd03d6c7636dcaa57cb32 204 SUPERFAMILY SSF54001 43 200 8.83E-28 T 31-10-2018 IPR038765 Papain-like cysteine peptidase superfamily TK1697 57b83e115e14fb43d6cbe655ebb82da1 177 Hamap MF_00590 UPF0218 protein . 7 173 30.05 T 31-10-2018 IPR007164 Protein of unknown function DUF359 TK1697 57b83e115e14fb43d6cbe655ebb82da1 177 PIRSF PIRSF006533 1 175 8.2E-55 T 31-10-2018 IPR007164 Protein of unknown function DUF359 TK1697 57b83e115e14fb43d6cbe655ebb82da1 177 Pfam PF04019 Protein of unknown function (DUF359) 50 171 4.5E-39 T 31-10-2018 IPR007164 Protein of unknown function DUF359 TK0967 7c8d4a0ff93c2577cc5de50ece0ebcf9 348 SUPERFAMILY SSF55920 123 347 7.07E-87 T 31-10-2018 IPR036005 Creatinase/aminopeptidase-like TK0967 7c8d4a0ff93c2577cc5de50ece0ebcf9 348 Gene3D G3DSA:3.40.350.10 1 122 7.5E-29 T 31-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal TK0967 7c8d4a0ff93c2577cc5de50ece0ebcf9 348 Gene3D G3DSA:3.90.230.10 123 348 1.9E-90 T 31-10-2018 TK0967 7c8d4a0ff93c2577cc5de50ece0ebcf9 348 Pfam PF00557 Metallopeptidase family M24 132 334 4.5E-71 T 31-10-2018 IPR000994 Peptidase M24 TK0967 7c8d4a0ff93c2577cc5de50ece0ebcf9 348 SUPERFAMILY SSF53092 6 124 7.15E-26 T 31-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal TK0967 7c8d4a0ff93c2577cc5de50ece0ebcf9 348 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 280 292 - T 31-10-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site TK0967 7c8d4a0ff93c2577cc5de50ece0ebcf9 348 Pfam PF01321 Creatinase/Prolidase N-terminal domain 2 124 9.2E-24 T 31-10-2018 IPR000587 Creatinase, N-terminal GO:0016787 TK0265 7718d205273b3d89c49a455680e81245 272 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 11 93 4.3E-30 T 31-10-2018 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 TK0265 7718d205273b3d89c49a455680e81245 272 SUPERFAMILY SSF53223 3 105 4.89E-34 T 31-10-2018 TK0265 7718d205273b3d89c49a455680e81245 272 TIGRFAM TIGR00507 aroE: shikimate dehydrogenase 8 266 8.4E-83 T 31-10-2018 IPR011342 Shikimate dehydrogenase GO:0004764|GO:0019632|GO:0050661|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 TK0265 7718d205273b3d89c49a455680e81245 272 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 118 191 4.0E-10 T 31-10-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase TK0265 7718d205273b3d89c49a455680e81245 272 SUPERFAMILY SSF51735 106 267 1.63E-41 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily TK0265 7718d205273b3d89c49a455680e81245 272 Gene3D G3DSA:3.40.50.10860 9 258 1.9E-92 T 31-10-2018 TK0265 7718d205273b3d89c49a455680e81245 272 Gene3D G3DSA:3.40.50.720 105 236 1.9E-92 T 31-10-2018 TK0265 7718d205273b3d89c49a455680e81245 272 Hamap MF_00222 Shikimate dehydrogenase (NADP(+)) [aroE]. 6 268 36.568 T 31-10-2018 IPR022893 Shikimate dehydrogenase family GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 TK1787 2fc1b8c8cf457fff7cc75f553855cc90 374 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 6 364 5.0E-41 T 31-10-2018 IPR002823 Protein of unknown function DUF112, transmembrane TK1212 ec63bcd64c4a78787ffe5232efaf8508 433 Pfam PF00860 Permease family 24 401 6.0E-96 T 31-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 TK1212 ec63bcd64c4a78787ffe5232efaf8508 433 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 348 368 - T 31-10-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 TK1212 ec63bcd64c4a78787ffe5232efaf8508 433 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 23 430 1.8E-97 T 31-10-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 TK1073 5d915a8eb8e7109c1499aab46af20961 101 Pfam PF01909 Nucleotidyltransferase domain 9 63 5.2E-13 T 31-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 TK1073 5d915a8eb8e7109c1499aab46af20961 101 SUPERFAMILY SSF81301 3 99 7.85E-22 T 31-10-2018 TK1073 5d915a8eb8e7109c1499aab46af20961 101 Gene3D G3DSA:3.30.460.10 1 98 2.2E-20 T 31-10-2018 TK0624 6b093a404a88adca257d4d1405976429 96 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 7 94 5.0E-18 T 31-10-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like TK1931 3aae2fa74bd3802dfc94309180bb48ec 101 Pfam PF11537 Protein of unknown function (DUF3227) 5 93 5.8E-35 T 31-10-2018 IPR021609 Protein of unknown function DUF3227 TK1931 3aae2fa74bd3802dfc94309180bb48ec 101 Gene3D G3DSA:1.10.1200.200 4 97 1.6E-26 T 31-10-2018 TK0008 74fedd5ada02c04f4d706a38cc218195 366 Gene3D G3DSA:3.40.50.150 169 342 6.2E-26 T 31-10-2018 TK0008 74fedd5ada02c04f4d706a38cc218195 366 SUPERFAMILY SSF53335 173 340 2.52E-21 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TK0008 74fedd5ada02c04f4d706a38cc218195 366 Pfam PF01170 Putative RNA methylase family UPF0020 175 321 5.5E-11 T 31-10-2018 IPR000241 Putative RNA methylase domain TK0376 6fa617ae81971f26ff24aef3b14ee51b 461 TIGRFAM TIGR02045 P_fruct_ADP: ADP-specific phosphofructokinase 13 458 1.6E-237 T 31-10-2018 IPR011790 ADP-specific phosphofructokinase, archaeal GO:0005737|GO:0006000|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.146|KEGG: 00030+2.7.1.146|KEGG: 00680+2.7.1.146|MetaCyc: PWY-6142 TK0376 6fa617ae81971f26ff24aef3b14ee51b 461 Hamap MF_00561 ADP-specific phosphofructokinase [pfkC]. 6 458 44.204 T 31-10-2018 IPR011790 ADP-specific phosphofructokinase, archaeal GO:0005737|GO:0006000|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.146|KEGG: 00030+2.7.1.146|KEGG: 00680+2.7.1.146|MetaCyc: PWY-6142 TK0376 6fa617ae81971f26ff24aef3b14ee51b 461 Gene3D G3DSA:3.30.1110.20 20 200 1.1E-157 T 31-10-2018 TK0376 6fa617ae81971f26ff24aef3b14ee51b 461 SUPERFAMILY SSF53613 12 457 2.53E-156 T 31-10-2018 IPR029056 Ribokinase-like TK0376 6fa617ae81971f26ff24aef3b14ee51b 461 Pfam PF04587 ADP-specific Phosphofructokinase/Glucokinase conserved region 14 449 1.8E-110 T 31-10-2018 IPR007666 ADP-specific phosphofructokinase/glucokinase GO:0005975|GO:0016773 Reactome: R-HSA-70171 TK0376 6fa617ae81971f26ff24aef3b14ee51b 461 PIRSF PIRSF015883 1 458 1.2E-201 T 31-10-2018 IPR015990 ADP-specific phosphofructokinase/glucokinase, archaeal GO:0000287|GO:0006096|GO:0016773 TK0376 6fa617ae81971f26ff24aef3b14ee51b 461 Gene3D G3DSA:3.40.1190.20 14 448 1.1E-157 T 31-10-2018 IPR029056 Ribokinase-like TK0796 76d9db505866e235285a52fb122acf33 139 SUPERFAMILY SSF46689 85 125 1.84E-8 T 31-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TK0796 76d9db505866e235285a52fb122acf33 139 Pfam PF02796 Helix-turn-helix domain of resolvase 85 123 9.1E-7 T 31-10-2018 IPR006120 Resolvase, HTH domain GO:0000150|GO:0003677|GO:0006310 TK0796 76d9db505866e235285a52fb122acf33 139 Gene3D G3DSA:1.10.10.60 85 127 4.8E-8 T 31-10-2018 TK0331 c8c1e7501279009ac1a7d36f977c8f8a 283 Gene3D G3DSA:3.40.630.30 1 161 2.6E-20 T 31-10-2018 TK0331 c8c1e7501279009ac1a7d36f977c8f8a 283 SUPERFAMILY SSF55729 2 194 2.66E-24 T 31-10-2018 IPR016181 Acyl-CoA N-acyltransferase TK0331 c8c1e7501279009ac1a7d36f977c8f8a 283 Pfam PF13508 Acetyltransferase (GNAT) domain 62 145 4.3E-14 T 31-10-2018 IPR000182 GNAT domain TK0730 3b18bb73a6875b2175e732e6da16f6f3 446 SUPERFAMILY SSF101960 16 442 3.01E-103 T 31-10-2018 IPR037284 SUF system FeS cluster assembly, SufBD superfamily TK0730 3b18bb73a6875b2175e732e6da16f6f3 446 Pfam PF01458 Uncharacterized protein family (UPF0051) 195 418 3.2E-55 T 31-10-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 TK1537 784c4e3de498d30f14e465e09873bbeb 156 SUPERFAMILY SSF54843 8 153 1.15E-47 T 31-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 TK1537 784c4e3de498d30f14e465e09873bbeb 156 ProSitePatterns PS00464 Ribosomal protein L22 signature. 127 151 - T 31-10-2018 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1537 784c4e3de498d30f14e465e09873bbeb 156 Gene3D G3DSA:3.90.470.10 6 156 2.2E-53 T 31-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 TK1537 784c4e3de498d30f14e465e09873bbeb 156 Pfam PF00237 Ribosomal protein L22p/L17e 21 151 1.4E-34 T 31-10-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 TK1537 784c4e3de498d30f14e465e09873bbeb 156 Hamap MF_01331_A 50S ribosomal protein L22 [rplV]. 4 154 33.882 T 31-10-2018 IPR005721 Ribosomal protein L22/L17, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1537 784c4e3de498d30f14e465e09873bbeb 156 TIGRFAM TIGR01038 uL22_arch_euk: ribosomal protein uL22 8 153 1.6E-67 T 31-10-2018 IPR005721 Ribosomal protein L22/L17, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK0963 fbc6896c87087142d37207f2e479a8c1 124 Gene3D G3DSA:1.20.120.330 2 122 9.2E-33 T 31-10-2018 TK0963 fbc6896c87087142d37207f2e479a8c1 124 SMART SM00748 7 113 8.2E-19 T 31-10-2018 IPR007842 HEPN domain TK0963 fbc6896c87087142d37207f2e479a8c1 124 SUPERFAMILY SSF81593 5 119 1.73E-30 T 31-10-2018 TK0963 fbc6896c87087142d37207f2e479a8c1 124 Pfam PF05168 HEPN domain 3 118 7.5E-32 T 31-10-2018 IPR007842 HEPN domain TK0968 f2d16c2b2c1d393c4dcbfceffbde037c 217 SUPERFAMILY SSF56784 4 186 6.8E-14 T 31-10-2018 IPR036412 HAD-like superfamily TK0968 f2d16c2b2c1d393c4dcbfceffbde037c 217 Gene3D G3DSA:1.10.150.520 15 84 2.3E-10 T 31-10-2018 TK0968 f2d16c2b2c1d393c4dcbfceffbde037c 217 Gene3D G3DSA:3.40.50.1000 4 134 2.3E-10 T 31-10-2018 IPR023214 HAD superfamily TK0968 f2d16c2b2c1d393c4dcbfceffbde037c 217 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 103 6.0E-6 T 31-10-2018 TK0158 575ef95f88e169c60d4fde869fb96a8f 334 Pfam PF00005 ABC transporter 22 160 1.8E-36 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TK0158 575ef95f88e169c60d4fde869fb96a8f 334 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TK0158 575ef95f88e169c60d4fde869fb96a8f 334 Gene3D G3DSA:3.40.50.300 3 236 8.0E-76 T 31-10-2018 TK0158 575ef95f88e169c60d4fde869fb96a8f 334 SMART SM00382 27 210 2.0E-16 T 31-10-2018 IPR003593 AAA+ ATPase domain TK0158 575ef95f88e169c60d4fde869fb96a8f 334 SUPERFAMILY SSF52540 5 241 3.38E-88 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK1417 9f0566e70ac1f6dc7bd766916babf4fb 216 Gene3D G3DSA:3.40.50.790 59 150 1.4E-77 T 31-10-2018 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich TK1417 9f0566e70ac1f6dc7bd766916babf4fb 216 PIRSF PIRSF002155 2 216 4.7E-68 T 31-10-2018 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1417 9f0566e70ac1f6dc7bd766916babf4fb 216 Gene3D G3DSA:3.30.190.20 13 213 1.4E-77 T 31-10-2018 TK1417 9f0566e70ac1f6dc7bd766916babf4fb 216 Pfam PF00687 Ribosomal protein L1p/L10e family 21 210 2.3E-50 T 31-10-2018 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein TK1417 9f0566e70ac1f6dc7bd766916babf4fb 216 ProSitePatterns PS01199 Ribosomal protein L1 signature. 114 133 - T 31-10-2018 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1417 9f0566e70ac1f6dc7bd766916babf4fb 216 Hamap MF_01318_A 50S ribosomal protein L1 [rplA]. 4 215 37.348 T 31-10-2018 IPR023669 Ribosomal protein L1, archaea GO:0003723|GO:0003735|GO:0006412|GO:0015934 TK1417 9f0566e70ac1f6dc7bd766916babf4fb 216 SUPERFAMILY SSF56808 7 214 8.37E-67 T 31-10-2018 IPR023674 Ribosomal protein L1-like TK0225 58547e2b730871366a5f603d99c17e4f 148 Gene3D G3DSA:1.10.10.10 55 135 3.7E-7 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TK0225 58547e2b730871366a5f603d99c17e4f 148 SUPERFAMILY SSF46785 54 138 4.69E-8 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TK2149 40fcfd4e110feceff62369fbbc3a0353 115 Pfam PF03788 LrgA family 15 107 4.1E-29 T 31-10-2018 IPR005538 LrgA/CidA family GO:0016021 TK2019 1fe12e8ce5205339eb8aecacc6e69de0 344 SUPERFAMILY SSF81345 6 339 7.72E-87 T 31-10-2018 IPR037294 ABC transporter, BtuC-like TK2019 1fe12e8ce5205339eb8aecacc6e69de0 344 Gene3D G3DSA:1.10.3470.10 8 343 6.5E-106 T 31-10-2018 IPR037294 ABC transporter, BtuC-like TK2019 1fe12e8ce5205339eb8aecacc6e69de0 344 Pfam PF01032 FecCD transport family 20 339 2.8E-97 T 31-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 TK0951 7ea214ff59e8701a4f2cf490aa677ec0 247 SUPERFAMILY SSF52540 1 239 3.07E-38 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK0951 7ea214ff59e8701a4f2cf490aa677ec0 247 Gene3D G3DSA:3.40.50.300 1 243 1.8E-56 T 31-10-2018 TK0951 7ea214ff59e8701a4f2cf490aa677ec0 247 Pfam PF03029 Conserved hypothetical ATP binding protein 6 241 1.0E-51 T 31-10-2018 IPR004130 GPN-loop GTPase TK1165 af113e1a8d4cb463f7fe71cb9ad0ff88 268 Pfam PF01261 Xylose isomerase-like TIM barrel 30 228 1.1E-15 T 31-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain TK1165 af113e1a8d4cb463f7fe71cb9ad0ff88 268 Gene3D G3DSA:3.20.20.150 5 254 4.6E-26 T 31-10-2018 TK1165 af113e1a8d4cb463f7fe71cb9ad0ff88 268 SUPERFAMILY SSF51658 11 238 2.36E-27 T 31-10-2018 IPR036237 Xylose isomerase-like superfamily TK1498 85da33e0b22704839fafd0f3364b3a7f 57 Hamap MF_00192 DNA-directed RNA polymerase subunit K [rpoK]. 2 57 21.829 T 31-10-2018 IPR006111 Archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 TK1498 85da33e0b22704839fafd0f3364b3a7f 57 PIRSF PIRSF000778 1 57 7.1E-23 T 31-10-2018 IPR006111 Archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 TK1498 85da33e0b22704839fafd0f3364b3a7f 57 Pfam PF01192 RNA polymerase Rpb6 5 51 2.3E-11 T 31-10-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 TK1498 85da33e0b22704839fafd0f3364b3a7f 57 ProSitePatterns PS01111 RNA polymerases K / 14 to 18 Kd subunits signature. 5 19 - T 31-10-2018 IPR020708 DNA-directed RNA polymerase, 14-18kDa subunit, conserved site GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 TK1498 85da33e0b22704839fafd0f3364b3a7f 57 SUPERFAMILY SSF63562 3 55 9.29E-21 T 31-10-2018 IPR036161 RPB6/omega subunit-like superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 TK1498 85da33e0b22704839fafd0f3364b3a7f 57 Gene3D G3DSA:3.90.940.50 1 57 8.7E-29 T 31-10-2018 TK1047 14ecc5b73707008d91ead2abbb43dd82 275 Gene3D G3DSA:1.20.120.420 1 95 2.4E-33 T 31-10-2018 IPR027363 Methylthioribose-1-phosphate isomerase, N-terminal KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 TK1047 14ecc5b73707008d91ead2abbb43dd82 275 Gene3D G3DSA:3.40.50.10470 96 275 4.8E-63 T 31-10-2018 TK1047 14ecc5b73707008d91ead2abbb43dd82 275 SUPERFAMILY SSF100950 5 272 1.5E-70 T 31-10-2018 IPR037171 NagB/RpiA transferase-like TK1047 14ecc5b73707008d91ead2abbb43dd82 275 Pfam PF01008 Initiation factor 2 subunit family 18 271 3.2E-52 T 31-10-2018 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 TK2063 72bfd889e202333aceb69e7ec02c881a 118 SUPERFAMILY SSF51182 6 106 1.52E-27 T 31-10-2018 IPR011051 RmlC-like cupin domain superfamily TK2063 72bfd889e202333aceb69e7ec02c881a 118 Pfam PF07883 Cupin domain 38 104 1.2E-15 T 31-10-2018 IPR013096 Cupin 2, conserved barrel TK2063 72bfd889e202333aceb69e7ec02c881a 118 Gene3D G3DSA:2.60.120.10 4 117 5.0E-34 T 31-10-2018 IPR014710 RmlC-like jelly roll fold TK0917 714eee0a981e2fb0a6dfb75cb1c85f7a 82 Pfam PF03683 Uncharacterised protein family (UPF0175) 5 77 8.7E-28 T 31-10-2018 IPR005368 Uncharacterised protein family UPF0175 TK2109 49c53dc9dfe745a9a9bcde59beb508aa 279 SMART SM00729 17 220 1.2E-4 T 31-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TK2109 49c53dc9dfe745a9a9bcde59beb508aa 279 SUPERFAMILY SSF102114 17 232 1.22E-28 T 31-10-2018 TK2109 49c53dc9dfe745a9a9bcde59beb508aa 279 Pfam PF04055 Radical SAM superfamily 24 163 3.9E-8 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TK2109 49c53dc9dfe745a9a9bcde59beb508aa 279 Gene3D G3DSA:3.20.20.70 9 248 1.1E-17 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TK0939 73415e487d51fe0bf03e653dfd8831e8 324 Pfam PF00288 GHMP kinases N terminal domain 76 136 4.5E-6 T 31-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 TK0939 73415e487d51fe0bf03e653dfd8831e8 324 PIRSF PIRSF004884 1 309 3.0E-102 T 31-10-2018 IPR004422 GHMP kinase group 1 KEGG: 00790+2.4.2.54|MetaCyc: PWY-6148 TK0939 73415e487d51fe0bf03e653dfd8831e8 324 TIGRFAM TIGR00144 beta_RFAP_syn: beta-ribofuranosylaminobenzene 5'-phosphate synthase family 2 307 2.4E-47 T 31-10-2018 IPR004422 GHMP kinase group 1 KEGG: 00790+2.4.2.54|MetaCyc: PWY-6148 TK0939 73415e487d51fe0bf03e653dfd8831e8 324 SUPERFAMILY SSF54211 1 148 1.97E-18 T 31-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TK0939 73415e487d51fe0bf03e653dfd8831e8 324 Gene3D G3DSA:3.30.230.10 16 141 7.9E-9 T 31-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TK1728 e98dec7e61c9089cea64fcc11c311b72 482 Gene3D G3DSA:2.60.120.260 29 151 2.7E-7 T 31-10-2018 IPR008979 Galactose-binding-like domain superfamily TK1823 402e9f8b0e1cb0f66fbe37f7805b0f65 66 TIGRFAM TIGR04140 chp_AF_0576: TIGR04140 family protein 1 66 1.6E-29 T 31-10-2018 IPR026486 Uncharacterised protein AF_0576 TK2195 cc1641086513d4a7c0fd403c17c61c9b 152 Hamap MF_00002 Aspartate carbamoyltransferase regulatory chain [pyrI]. 2 150 34.394 T 31-10-2018 IPR002801 Aspartate transcarbamylase regulatory subunit GO:0006207|GO:0009347 TK2195 cc1641086513d4a7c0fd403c17c61c9b 152 TIGRFAM TIGR00240 ATCase_reg: aspartate carbamoyltransferase, regulatory subunit 3 149 1.1E-61 T 31-10-2018 IPR002801 Aspartate transcarbamylase regulatory subunit GO:0006207|GO:0009347 TK2195 cc1641086513d4a7c0fd403c17c61c9b 152 Gene3D G3DSA:2.30.30.20 99 152 1.6E-23 T 31-10-2018 TK2195 cc1641086513d4a7c0fd403c17c61c9b 152 ProDom PD006194 REGULATORY ASPARTATE CARBAMOYLTRANSFERASE CHAIN METAL-BINDING ZINC PYRIMIDINE BIOSYNTHESIS SUBUNIT TRANSFERASE 7 98 3.0E-45 T 31-10-2018 IPR020545 Aspartate carbamoyltransferase regulatory subunit, N-terminal TK2195 cc1641086513d4a7c0fd403c17c61c9b 152 Pfam PF02748 Aspartate carbamoyltransferase regulatory chain, metal binding domain 101 148 4.9E-22 T 31-10-2018 IPR020542 Aspartate carbamoyltransferase regulatory subunit, C-terminal TK2195 cc1641086513d4a7c0fd403c17c61c9b 152 SUPERFAMILY SSF54893 3 99 7.59E-33 T 31-10-2018 IPR036793 Aspartate carbamoyltransferase regulatory subunit, N-terminal domain superfamily TK2195 cc1641086513d4a7c0fd403c17c61c9b 152 Gene3D G3DSA:3.30.70.140 1 98 1.2E-36 T 31-10-2018 IPR036793 Aspartate carbamoyltransferase regulatory subunit, N-terminal domain superfamily TK2195 cc1641086513d4a7c0fd403c17c61c9b 152 Pfam PF01948 Aspartate carbamoyltransferase regulatory chain, allosteric domain 5 97 8.9E-33 T 31-10-2018 IPR020545 Aspartate carbamoyltransferase regulatory subunit, N-terminal TK2195 cc1641086513d4a7c0fd403c17c61c9b 152 SUPERFAMILY SSF57825 101 149 3.27E-17 T 31-10-2018 IPR036792 Aspartate carbamoyltransferase regulatory subunit, C-terminal domain superfamily TK1956 55d22d4ff240811f747de0cec34e90e5 351 SUPERFAMILY SSF52540 11 164 8.78E-12 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK1956 55d22d4ff240811f747de0cec34e90e5 351 Gene3D G3DSA:3.40.50.300 12 213 1.4E-25 T 31-10-2018 TK1956 55d22d4ff240811f747de0cec34e90e5 351 Pfam PF16575 mRNA cleavage and polyadenylation factor CLP1 P-loop 34 208 2.5E-38 T 31-10-2018 IPR032319 Polyribonucleotide 5'-hydroxyl-kinase Clp1, P-loop domain TK0831 15ffc4b770e62df318d093226fa9acb3 52 SUPERFAMILY SSF52833 2 51 9.79E-8 T 31-10-2018 IPR036249 Thioredoxin-like superfamily TK0831 15ffc4b770e62df318d093226fa9acb3 52 Gene3D G3DSA:3.40.30.10 1 51 1.4E-9 T 31-10-2018 TK0831 15ffc4b770e62df318d093226fa9acb3 52 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 21 42 8.4E-6 T 31-10-2018 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 TK0192 b4162c96a4733f10afa358ed15abbeab 72 SUPERFAMILY SSF141694 6 64 7.59E-13 T 31-10-2018 TK0192 b4162c96a4733f10afa358ed15abbeab 72 Pfam PF01954 Protein of unknown function DUF104 6 64 1.3E-17 T 31-10-2018 IPR008203 Uncharacterised protein family UPF0165 TK0192 b4162c96a4733f10afa358ed15abbeab 72 Gene3D G3DSA:4.10.1150.10 5 71 4.2E-12 T 31-10-2018 IPR024069 AF2212-like domain superfamily TK1655 5509b693f8bed234ff96fa0e0d3f82ad 398 SUPERFAMILY SSF103473 18 396 5.75E-60 T 31-10-2018 IPR036259 MFS transporter superfamily TK1655 5509b693f8bed234ff96fa0e0d3f82ad 398 Gene3D G3DSA:1.20.1250.20 217 398 1.1E-22 T 31-10-2018 TK1655 5509b693f8bed234ff96fa0e0d3f82ad 398 Pfam PF07690 Major Facilitator Superfamily 24 267 7.0E-26 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TK1655 5509b693f8bed234ff96fa0e0d3f82ad 398 Gene3D G3DSA:1.20.1250.20 17 212 3.4E-26 T 31-10-2018 TK2045 36ec0a2eb85ed8c7928e4da473349167 290 Gene3D G3DSA:3.40.50.150 119 289 2.2E-26 T 31-10-2018 TK2045 36ec0a2eb85ed8c7928e4da473349167 290 SUPERFAMILY SSF53335 91 266 3.72E-35 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TK2045 36ec0a2eb85ed8c7928e4da473349167 290 Pfam PF13649 Methyltransferase domain 131 232 1.5E-9 T 31-10-2018 TK0214 48cdba671db8d7be96ecde04bc93e194 659 Pfam PF01568 Molydopterin dinucleotide binding domain 552 651 3.2E-23 T 31-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 TK0214 48cdba671db8d7be96ecde04bc93e194 659 Gene3D G3DSA:2.40.40.20 540 659 1.9E-34 T 31-10-2018 TK0214 48cdba671db8d7be96ecde04bc93e194 659 Gene3D G3DSA:3.40.228.10 129 326 2.4E-167 T 31-10-2018 TK0214 48cdba671db8d7be96ecde04bc93e194 659 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 3 47 3.6E-7 T 31-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TK0214 48cdba671db8d7be96ecde04bc93e194 659 Gene3D G3DSA:3.40.50.740 58 516 2.4E-167 T 31-10-2018 TK0214 48cdba671db8d7be96ecde04bc93e194 659 SUPERFAMILY SSF50692 521 658 2.1E-38 T 31-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily TK0214 48cdba671db8d7be96ecde04bc93e194 659 Gene3D G3DSA:2.20.25.90 2 49 2.3E-8 T 31-10-2018 TK0214 48cdba671db8d7be96ecde04bc93e194 659 SMART SM00926 1 49 7.0E-6 T 31-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TK0214 48cdba671db8d7be96ecde04bc93e194 659 TIGRFAM TIGR01591 Fdh-alpha: formate dehydrogenase, alpha subunit 4 656 1.4E-262 T 31-10-2018 IPR006478 Formate dehydrogenase, alpha subunit GO:0008863|GO:0015942|GO:0055114 KEGG: 00630+1.17.1.9|KEGG: 00680+1.17.1.9|MetaCyc: PWY-1881|MetaCyc: PWY-5497|MetaCyc: PWY-6696|MetaCyc: PWY-7985 TK0214 48cdba671db8d7be96ecde04bc93e194 659 SUPERFAMILY SSF53706 2 554 1.02E-193 T 31-10-2018 TK0214 48cdba671db8d7be96ecde04bc93e194 659 Pfam PF00384 Molybdopterin oxidoreductase 52 473 9.3E-86 T 31-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TK0542 e3b7dda0e4497b1f816b91c474ceeb7e 152 Pfam PF01850 PIN domain 6 146 1.0E-12 T 31-10-2018 IPR002716 PIN domain TK0542 e3b7dda0e4497b1f816b91c474ceeb7e 152 SUPERFAMILY SSF88723 6 145 2.94E-13 T 31-10-2018 IPR029060 PIN-like domain superfamily TK0542 e3b7dda0e4497b1f816b91c474ceeb7e 152 Gene3D G3DSA:3.40.50.1010 5 150 7.7E-9 T 31-10-2018 TK0751 00ca5c60934f58e27c569e4451c9d116 217 TIGRFAM TIGR04288 CGP_CTERM: CGP-CTERM domain 195 214 1.4E-7 T 31-10-2018 IPR027552 CGP-CTERM domain TK1324 a76c3d54d2f8d168ee4f9e579a2e46ce 264 Pfam PF01040 UbiA prenyltransferase family 24 236 1.7E-32 T 31-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 TK1324 a76c3d54d2f8d168ee4f9e579a2e46ce 264 Gene3D G3DSA:1.10.357.140 18 165 8.4E-12 T 31-10-2018 TK1955 dd4420a3e4f84bff567a722d4b6dd9a6 154 Pfam PF01037 Lrp/AsnC ligand binding domain 87 153 8.9E-9 T 31-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain TK1955 dd4420a3e4f84bff567a722d4b6dd9a6 154 SUPERFAMILY SSF46785 31 136 2.4E-10 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TK1955 dd4420a3e4f84bff567a722d4b6dd9a6 154 Gene3D G3DSA:3.30.70.920 82 154 9.4E-11 T 31-10-2018 TK1955 dd4420a3e4f84bff567a722d4b6dd9a6 154 SMART SM00418 5 105 0.0039 T 31-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TK1955 dd4420a3e4f84bff567a722d4b6dd9a6 154 Pfam PF12802 MarR family 7 65 1.2E-7 T 31-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TK1955 dd4420a3e4f84bff567a722d4b6dd9a6 154 SMART SM00419 21 72 2.3E-8 T 31-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 TK1955 dd4420a3e4f84bff567a722d4b6dd9a6 154 Gene3D G3DSA:1.10.10.10 6 81 7.9E-8 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TK0865 3aed042757dee32dc52cd8fdadd6cc34 351 Gene3D G3DSA:3.40.50.1980 74 204 6.0E-36 T 31-10-2018 TK0865 3aed042757dee32dc52cd8fdadd6cc34 351 SUPERFAMILY SSF53807 71 335 2.71E-71 T 31-10-2018 TK0865 3aed042757dee32dc52cd8fdadd6cc34 351 Gene3D G3DSA:3.40.50.1980 208 335 5.5E-36 T 31-10-2018 TK0865 3aed042757dee32dc52cd8fdadd6cc34 351 Pfam PF01497 Periplasmic binding protein 92 309 1.3E-39 T 31-10-2018 IPR002491 ABC transporter periplasmic binding domain TK0303 f5877054ec50c25be283b189936ec4b9 583 Gene3D G3DSA:3.60.10.10 358 583 1.1E-32 T 31-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily TK0303 f5877054ec50c25be283b189936ec4b9 583 SUPERFAMILY SSF56219 353 581 1.44E-31 T 31-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily TK0303 f5877054ec50c25be283b189936ec4b9 583 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 376 573 1.1E-6 T 31-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase TK0807 d2323e2760707a6a86f85e45f9bb2708 383 SUPERFAMILY SSF53335 56 198 3.44E-20 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TK0807 d2323e2760707a6a86f85e45f9bb2708 383 Pfam PF13847 Methyltransferase domain 86 157 1.1E-7 T 31-10-2018 IPR025714 Methyltransferase domain TK0807 d2323e2760707a6a86f85e45f9bb2708 383 Gene3D G3DSA:3.40.50.150 41 236 6.1E-28 T 31-10-2018 TK0120 089504aee40de855fde5df863953d323 172 Pfam PF00037 4Fe-4S binding domain 67 88 3.7E-7 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TK0120 089504aee40de855fde5df863953d323 172 SUPERFAMILY SSF54862 4 156 5.15E-20 T 31-10-2018 TK0120 089504aee40de855fde5df863953d323 172 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 74 85 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TK0120 089504aee40de855fde5df863953d323 172 Gene3D G3DSA:3.30.70.20 37 106 1.7E-12 T 31-10-2018 TK2051 9443cf932aad5efbcd9e01ea8046a2b9 216 SUPERFAMILY SSF56112 9 155 3.99E-14 T 31-10-2018 IPR011009 Protein kinase-like domain superfamily TK0137 e804b43ee969441b3d7ab39db7095fb6 153 Gene3D G3DSA:3.40.50.1010 1 130 5.7E-10 T 31-10-2018 TK0137 e804b43ee969441b3d7ab39db7095fb6 153 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 2 132 10.068 T 31-10-2018 IPR022907 VapC family GO:0004540 TK0137 e804b43ee969441b3d7ab39db7095fb6 153 Pfam PF01850 PIN domain 3 125 1.0E-12 T 31-10-2018 IPR002716 PIN domain TK0137 e804b43ee969441b3d7ab39db7095fb6 153 SUPERFAMILY SSF88723 1 133 2.66E-15 T 31-10-2018 IPR029060 PIN-like domain superfamily TK1507 b23c0974d2c2fc5e5abe3bfa7ef63ac6 195 Gene3D G3DSA:3.40.50.150 5 193 2.8E-49 T 31-10-2018 TK1507 b23c0974d2c2fc5e5abe3bfa7ef63ac6 195 Pfam PF05175 Methyltransferase small domain 28 191 5.3E-44 T 31-10-2018 IPR007848 Methyltransferase small domain GO:0008168 TK1507 b23c0974d2c2fc5e5abe3bfa7ef63ac6 195 SUPERFAMILY SSF53335 8 190 3.49E-41 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TK0345 4cf9d87599e859371f273fb28b15f507 280 SMART SM00478 112 270 2.1E-18 T 31-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 TK0345 4cf9d87599e859371f273fb28b15f507 280 Gene3D G3DSA:1.10.340.30 102 217 8.2E-27 T 31-10-2018 TK0345 4cf9d87599e859371f273fb28b15f507 280 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 108 251 2.0E-13 T 31-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 TK0345 4cf9d87599e859371f273fb28b15f507 280 SUPERFAMILY SSF48150 91 269 6.11E-37 T 31-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 TK0345 4cf9d87599e859371f273fb28b15f507 280 Gene3D G3DSA:1.10.1670.10 218 275 3.2E-8 T 31-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 TK1126 5aac1c55ae4a5940b1e35bcd0ec3f9b9 170 SUPERFAMILY SSF53323 2 168 4.97E-42 T 31-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 TK1126 5aac1c55ae4a5940b1e35bcd0ec3f9b9 170 Gene3D G3DSA:3.40.920.10 1 170 6.6E-54 T 31-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 TK1126 5aac1c55ae4a5940b1e35bcd0ec3f9b9 170 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 9 166 4.3E-38 T 31-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 TK0709 11f3232a69ecf5edc1ee636d9ad8aa34 253 SUPERFAMILY SSF56524 38 158 4.84E-6 T 31-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 TK0193 22ad1b450b31d4847b914879e02d9856 307 SUPERFAMILY SSF52402 2 224 4.19E-55 T 31-10-2018 TK0193 22ad1b450b31d4847b914879e02d9856 307 Pfam PF00958 GMP synthase C terminal domain 217 306 6.3E-35 T 31-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 TK0193 22ad1b450b31d4847b914879e02d9856 307 SUPERFAMILY SSF54810 189 307 1.7E-45 T 31-10-2018 TK0193 22ad1b450b31d4847b914879e02d9856 307 Pfam PF02540 NAD synthase 4 81 2.0E-6 T 31-10-2018 IPR022310 NAD/GMP synthase TK0193 22ad1b450b31d4847b914879e02d9856 307 Pfam PF02540 NAD synthase 157 186 7.3E-5 T 31-10-2018 IPR022310 NAD/GMP synthase TK0193 22ad1b450b31d4847b914879e02d9856 307 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 4 307 1.7E-152 T 31-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 TK0193 22ad1b450b31d4847b914879e02d9856 307 Hamap MF_00345 GMP synthase [glutamine-hydrolyzing] subunit B [guaAB]. 1 307 46.044 T 31-10-2018 IPR026598 GMP synthase subunit B KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 TK0193 22ad1b450b31d4847b914879e02d9856 307 Gene3D G3DSA:3.30.300.10 190 307 4.6E-54 T 31-10-2018 TK0193 22ad1b450b31d4847b914879e02d9856 307 Gene3D G3DSA:3.40.50.620 2 189 9.3E-79 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TK0525 65ddff531e58df9790540b23cc5affc9 115 TIGRFAM TIGR00332 neela_ferrous: desulfoferrodoxin ferrous iron-binding domain 8 114 7.2E-33 T 31-10-2018 IPR002742 Desulfoferrodoxin, ferrous iron-binding domain GO:0005506|GO:0016491|GO:0055114 TK0525 65ddff531e58df9790540b23cc5affc9 115 Gene3D G3DSA:2.60.40.730 1 115 5.6E-51 T 31-10-2018 IPR036073 Desulfoferrodoxin, ferrous iron-binding domain superfamily GO:0005506|GO:0016491|GO:0055114 TK0525 65ddff531e58df9790540b23cc5affc9 115 Pfam PF01880 Desulfoferrodoxin 9 111 4.6E-32 T 31-10-2018 IPR002742 Desulfoferrodoxin, ferrous iron-binding domain GO:0005506|GO:0016491|GO:0055114 TK0525 65ddff531e58df9790540b23cc5affc9 115 SUPERFAMILY SSF49367 1 114 3.66E-39 T 31-10-2018 IPR036073 Desulfoferrodoxin, ferrous iron-binding domain superfamily GO:0005506|GO:0016491|GO:0055114 TK0833 ad6a4ace12390cae1fcb98a6463558c6 379 Pfam PF07690 Major Facilitator Superfamily 10 332 1.5E-15 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TK0833 ad6a4ace12390cae1fcb98a6463558c6 379 Gene3D G3DSA:1.20.1250.20 7 369 3.0E-25 T 31-10-2018 TK0833 ad6a4ace12390cae1fcb98a6463558c6 379 SUPERFAMILY SSF103473 9 372 2.62E-28 T 31-10-2018 IPR036259 MFS transporter superfamily TK0022 d0f915cb3626d21d2964c0e14ab6c304 334 Pfam PF12773 Double zinc ribbon 289 330 5.3E-10 T 31-10-2018 IPR025874 Double zinc ribbon TK0022 d0f915cb3626d21d2964c0e14ab6c304 334 SUPERFAMILY SSF117892 75 203 1.96E-13 T 31-10-2018 IPR036013 Band 7/SPFH domain superfamily TK0022 d0f915cb3626d21d2964c0e14ab6c304 334 Pfam PF13421 SPFH domain-Band 7 family 16 204 2.2E-37 T 31-10-2018 IPR033880 SPFH domain, YdjI-like TK1649 385a3075e468cb3ac03d78c45090e08b 345 Pfam PF01594 AI-2E family transporter 11 322 1.1E-36 T 31-10-2018 IPR002549 Transmembrane protein TqsA-like TK2198 8478268faaa6237ec2313ca7e2fd5b27 137 Gene3D G3DSA:2.60.120.460 1 137 1.2E-50 T 31-10-2018 IPR035917 YjbQ-like superfamily TK2198 8478268faaa6237ec2313ca7e2fd5b27 137 Pfam PF01894 Uncharacterised protein family UPF0047 20 134 7.9E-37 T 31-10-2018 IPR001602 Uncharacterised protein family UPF0047 TK2198 8478268faaa6237ec2313ca7e2fd5b27 137 SUPERFAMILY SSF111038 1 137 1.31E-44 T 31-10-2018 IPR035917 YjbQ-like superfamily TK2198 8478268faaa6237ec2313ca7e2fd5b27 137 TIGRFAM TIGR00149 TIGR00149_YjbQ: secondary thiamine-phosphate synthase enzyme 9 137 2.8E-38 T 31-10-2018 IPR001602 Uncharacterised protein family UPF0047 TK2198 8478268faaa6237ec2313ca7e2fd5b27 137 PIRSF PIRSF004681 1 137 1.2E-38 T 31-10-2018 IPR001602 Uncharacterised protein family UPF0047 TK0813 a875255a4625c5b3201b3da3644bc565 151 PIRSF PIRSF037214 1 139 1.5E-57 T 31-10-2018 IPR017140 Uncharacterised conserved protein UCP037214 TK0813 a875255a4625c5b3201b3da3644bc565 151 Pfam PF10015 Uncharacterized protein conserved in archaea (DUF2258) 3 73 1.2E-24 T 31-10-2018 IPR017140 Uncharacterised conserved protein UCP037214 TK0187 776c0e24536b54245cc5a220c1aee75f 283 Gene3D G3DSA:3.40.50.880 1 246 3.8E-62 T 31-10-2018 IPR029062 Class I glutamine amidotransferase-like TK0187 776c0e24536b54245cc5a220c1aee75f 283 SUPERFAMILY SSF52317 2 240 3.96E-34 T 31-10-2018 IPR029062 Class I glutamine amidotransferase-like TK0187 776c0e24536b54245cc5a220c1aee75f 283 Pfam PF07722 Peptidase C26 14 218 1.6E-51 T 31-10-2018 IPR011697 Peptidase C26 GO:0016787 Reactome: R-HSA-6798695 TK0247 5917a8c151acffe0231792e24023f86d 233 SUPERFAMILY SSF51366 1 225 1.33E-50 T 31-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 TK0247 5917a8c151acffe0231792e24023f86d 233 Pfam PF00977 Histidine biosynthesis protein 3 218 1.9E-57 T 31-10-2018 IPR006062 Histidine biosynthesis GO:0000105 TK0247 5917a8c151acffe0231792e24023f86d 233 Gene3D G3DSA:3.20.20.70 3 232 2.2E-66 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TK0247 5917a8c151acffe0231792e24023f86d 233 Hamap MF_01014 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [hisA]. 2 226 29.814 T 31-10-2018 IPR023016 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 TK1124 d6dd9727e13d98d5c79f62e91a44ba2d 281 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 56 202 1.1E-35 T 31-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 TK1124 d6dd9727e13d98d5c79f62e91a44ba2d 281 Gene3D G3DSA:3.40.50.970 84 252 6.4E-29 T 31-10-2018 TK1124 d6dd9727e13d98d5c79f62e91a44ba2d 281 SUPERFAMILY SSF52518 19 272 9.11E-75 T 31-10-2018 IPR029061 Thiamin diphosphate-binding fold TK0684 4d185cebda52abe166fcb325ac86d9ad 364 Pfam PF03222 Tryptophan/tyrosine permease family 33 363 3.2E-27 T 31-10-2018 IPR018227 Amino acid/polyamine transporter 2 GO:0003333 TK1103 4b229339816e5fab4bcc55bf6d2c9ed1 204 Gene3D G3DSA:1.10.1760.20 1 196 3.6E-63 T 31-10-2018 TK1103 4b229339816e5fab4bcc55bf6d2c9ed1 204 Pfam PF01891 Cobalt uptake substrate-specific transmembrane region 2 198 3.3E-61 T 31-10-2018 IPR002751 Metal transport protein CbiM/NikMN GO:0000041|GO:0016021 TK1113 0ac6e286cf9fe1b230a4514ca81da06b 227 Pfam PF01963 TraB family 9 217 2.8E-12 T 31-10-2018 IPR002816 Pheromone shutdown, TraB TK1882 edae17f4010b74e21d9fe631564bc0ba 101 ProDom PD012512 ARCHAEA PH1931 STS176 TA1183 MJ0319 PRECURSOR TVG0378908 UNCHARACTERIZED DUF211 AF1549 12 95 3.0E-41 T 31-10-2018 IPR003831 Protein of unknown function DUF211 TK1882 edae17f4010b74e21d9fe631564bc0ba 101 Pfam PF02680 Uncharacterized ArCR, COG1888 5 91 2.8E-38 T 31-10-2018 IPR003831 Protein of unknown function DUF211 TK1882 edae17f4010b74e21d9fe631564bc0ba 101 Gene3D G3DSA:3.30.70.1340 1 86 7.2E-35 T 31-10-2018 IPR023129 MTH889-like domain superfamily TK1882 edae17f4010b74e21d9fe631564bc0ba 101 SUPERFAMILY SSF160363 4 93 1.83E-34 T 31-10-2018 IPR023129 MTH889-like domain superfamily TK0614 cfbd93092aee5a9cd2e877d65244b3ad 317 Gene3D G3DSA:1.10.443.10 119 296 3.0E-40 T 31-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 TK0614 cfbd93092aee5a9cd2e877d65244b3ad 317 SUPERFAMILY SSF56349 26 278 2.04E-12 T 31-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 TK0614 cfbd93092aee5a9cd2e877d65244b3ad 317 Pfam PF16795 Archaeal phage integrase 119 292 3.2E-60 T 31-10-2018 IPR031857 Integrase SSV1, C-terminal TK1566 b97cdde07dfb24baae64a8eda9c8be53 476 PIRSF PIRSF008315 1 476 3.4E-226 T 31-10-2018 IPR016539 Uncharacterised conserved protein UCP008315 TK1803 1f1c7ab22aab50dd93a707477d7e3873 349 Gene3D G3DSA:1.10.3720.10 111 337 3.9E-16 T 31-10-2018 IPR035906 MetI-like superfamily TK1803 1f1c7ab22aab50dd93a707477d7e3873 349 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 139 342 1.5E-37 T 31-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TK1803 1f1c7ab22aab50dd93a707477d7e3873 349 SUPERFAMILY SSF161098 117 325 2.88E-13 T 31-10-2018 IPR035906 MetI-like superfamily TK1120 82f62425fa5afd3030c2a0bea981c78d 157 Pfam PF02643 Uncharacterized ACR, COG1430 14 114 2.1E-18 T 31-10-2018 IPR003795 Protein of unknown function DUF192 TK1120 82f62425fa5afd3030c2a0bea981c78d 157 Hamap MF_00263 UPF0127 protein . 2 116 29.183 T 31-10-2018 IPR022906 Uncharacterised protein family UPF0127 TK1120 82f62425fa5afd3030c2a0bea981c78d 157 Gene3D G3DSA:2.60.120.1140 1 123 3.5E-14 T 31-10-2018 IPR038695 Saro_0823-like superfamily TK1867 5b0594d472a281841d0029a62fd1e332 276 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 13 267 1.3E-64 T 31-10-2018 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 TK1867 5b0594d472a281841d0029a62fd1e332 276 Gene3D G3DSA:1.10.3720.10 57 275 1.1E-26 T 31-10-2018 IPR035906 MetI-like superfamily TK1867 5b0594d472a281841d0029a62fd1e332 276 SUPERFAMILY SSF161098 20 265 7.98E-33 T 31-10-2018 IPR035906 MetI-like superfamily TK1867 5b0594d472a281841d0029a62fd1e332 276 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 83 267 1.1E-14 T 31-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TK1527 b8384a77b20d0948ce5a60d5b899bbf4 56 Hamap MF_01364_A 30S ribosomal protein S14 type Z [rpsZ]. 2 56 17.52 T 31-10-2018 IPR023676 Ribosomal protein S14, type Z, archaeal GO:0003723|GO:0003735|GO:0006412|GO:0015935 TK1527 b8384a77b20d0948ce5a60d5b899bbf4 56 ProSitePatterns PS00527 Ribosomal protein S14 signature. 23 44 - T 31-10-2018 IPR018271 Ribosomal protein S14, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1527 b8384a77b20d0948ce5a60d5b899bbf4 56 Gene3D G3DSA:4.10.830.10 1 56 4.3E-20 T 31-10-2018 TK1527 b8384a77b20d0948ce5a60d5b899bbf4 56 Pfam PF00253 Ribosomal protein S14p/S29e 8 55 5.4E-9 T 31-10-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TK2034 c7cb72a41064abf88e5bc09ad0c25392 278 SUPERFAMILY SSF52402 1 133 5.53E-27 T 31-10-2018 TK2034 c7cb72a41064abf88e5bc09ad0c25392 278 Gene3D G3DSA:3.40.50.620 1 142 1.4E-29 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TK2034 c7cb72a41064abf88e5bc09ad0c25392 278 SUPERFAMILY SSF52402 151 276 3.68E-23 T 31-10-2018 TK2034 c7cb72a41064abf88e5bc09ad0c25392 278 Pfam PF00582 Universal stress protein family 1 133 3.9E-21 T 31-10-2018 IPR006016 UspA TK2034 c7cb72a41064abf88e5bc09ad0c25392 278 Pfam PF00582 Universal stress protein family 154 276 1.4E-15 T 31-10-2018 IPR006016 UspA TK2034 c7cb72a41064abf88e5bc09ad0c25392 278 PRINTS PR01438 Universal stress protein signature 236 248 1.8E-17 T 31-10-2018 IPR006015 Universal stress protein A TK2034 c7cb72a41064abf88e5bc09ad0c25392 278 PRINTS PR01438 Universal stress protein signature 2 20 1.8E-17 T 31-10-2018 IPR006015 Universal stress protein A TK2034 c7cb72a41064abf88e5bc09ad0c25392 278 PRINTS PR01438 Universal stress protein signature 254 276 1.8E-17 T 31-10-2018 IPR006015 Universal stress protein A TK2034 c7cb72a41064abf88e5bc09ad0c25392 278 Gene3D G3DSA:3.40.50.620 148 278 6.3E-26 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TK0602 4348caaabed73f5beb7581dff5ad4d79 266 Gene3D G3DSA:3.40.50.300 5 246 4.4E-6 T 31-10-2018 TK0295 6c4073dacc06c84b6a1f1804d161ed03 274 Pfam PF00209 Sodium:neurotransmitter symporter family 13 121 3.6E-5 T 31-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 TK0295 6c4073dacc06c84b6a1f1804d161ed03 274 SUPERFAMILY SSF161070 21 269 1.26E-18 T 31-10-2018 IPR037272 Sodium:neurotransmitter symporter superfamily GO:0005328 TK0934 d9009a7a5de3fe22519cdde026d4d703 244 Pfam PF04060 Putative Fe-S cluster 160 191 2.5E-8 T 31-10-2018 IPR007202 4Fe-4S domain GO:0051536 TK0934 d9009a7a5de3fe22519cdde026d4d703 244 Pfam PF03205 Molybdopterin guanine dinucleotide synthesis protein B 4 111 1.2E-17 T 31-10-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 TK0934 d9009a7a5de3fe22519cdde026d4d703 244 SUPERFAMILY SSF52540 1 116 5.04E-12 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK0934 d9009a7a5de3fe22519cdde026d4d703 244 TIGRFAM TIGR00176 mobB: molybdopterin-guanine dinucleotide biosynthesis protein B 5 142 9.9E-23 T 31-10-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 TK0934 d9009a7a5de3fe22519cdde026d4d703 244 Gene3D G3DSA:3.40.50.300 1 157 1.9E-28 T 31-10-2018 TK0934 d9009a7a5de3fe22519cdde026d4d703 244 Gene3D G3DSA:3.20.20.20 158 222 7.0E-6 T 31-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TK1866 b6dc7fae112033df03900c4ff1eb2e4c 306 SUPERFAMILY SSF161098 15 292 1.05E-28 T 31-10-2018 IPR035906 MetI-like superfamily TK1866 b6dc7fae112033df03900c4ff1eb2e4c 306 Gene3D G3DSA:1.10.3720.10 61 304 5.9E-27 T 31-10-2018 IPR035906 MetI-like superfamily TK1866 b6dc7fae112033df03900c4ff1eb2e4c 306 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 97 292 5.8E-12 T 31-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TK1866 b6dc7fae112033df03900c4ff1eb2e4c 306 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 7 300 2.5E-89 T 31-10-2018 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 TK2014 d20c4d49cf5ae8d89d30d5ea40a97650 244 Pfam PF01925 Sulfite exporter TauE/SafE 8 239 5.0E-43 T 31-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 TK1559 451b428dee4338a00e4fd2953e9c3134 380 Pfam PF00999 Sodium/hydrogen exchanger family 9 376 2.0E-62 T 31-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 TK1559 451b428dee4338a00e4fd2953e9c3134 380 Gene3D G3DSA:1.20.1530.20 1 380 3.0E-96 T 31-10-2018 IPR038770 Sodium/solute symporter superfamily TK2223 98477dc4de028df7abb50ecb9abea913 337 Gene3D G3DSA:3.30.300.110 64 146 1.1E-13 T 31-10-2018 TK2223 98477dc4de028df7abb50ecb9abea913 337 Pfam PF02475 Met-10+ like-protein 89 266 2.8E-36 T 31-10-2018 IPR030382 SAM-dependent methyltransferase TRM5/TYW2-type Reactome: R-HSA-6782861 TK2223 98477dc4de028df7abb50ecb9abea913 337 Gene3D G3DSA:3.40.50.150 150 336 5.5E-34 T 31-10-2018 TK2223 98477dc4de028df7abb50ecb9abea913 337 SUPERFAMILY SSF53335 87 335 4.46E-45 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TK2039 d57da8efa50748a86f1a8a14a0255166 356 SUPERFAMILY SSF48452 15 332 7.99E-13 T 31-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TK2039 d57da8efa50748a86f1a8a14a0255166 356 Gene3D G3DSA:1.25.40.10 1 356 8.4E-71 T 31-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TK1263 382783e7e7e75257afc01b2ab9955a24 262 ProDom PD033097 PH0063 MJ0596 ARCHAEAL PF2050 138 262 1.0E-65 T 31-10-2018 IPR022620 Protein of unknown function DUF2666 TK1263 382783e7e7e75257afc01b2ab9955a24 262 ProDom PD033097 PH0063 MJ0596 ARCHAEAL PF2050 4 93 2.0E-46 T 31-10-2018 IPR022620 Protein of unknown function DUF2666 TK1263 382783e7e7e75257afc01b2ab9955a24 262 Pfam PF10869 Protein of unknown function (DUF2666) 4 117 6.2E-12 T 31-10-2018 IPR022620 Protein of unknown function DUF2666 TK1263 382783e7e7e75257afc01b2ab9955a24 262 Pfam PF10869 Protein of unknown function (DUF2666) 138 262 1.4E-48 T 31-10-2018 IPR022620 Protein of unknown function DUF2666 TK1033 cec157bf42ef56797095213f1a924b66 132 Gene3D G3DSA:3.40.140.10 3 132 2.9E-30 T 31-10-2018 TK1033 cec157bf42ef56797095213f1a924b66 132 SUPERFAMILY SSF102712 2 127 2.35E-23 T 31-10-2018 TK1033 cec157bf42ef56797095213f1a924b66 132 SMART SM00232 2 129 4.3E-14 T 31-10-2018 IPR000555 JAB1/MPN/MOV34 metalloenzyme domain GO:0005515 TK1033 cec157bf42ef56797095213f1a924b66 132 Pfam PF14464 Prokaryotic homologs of the JAB domain 15 119 5.7E-18 T 31-10-2018 IPR028090 JAB domain, prokaryotic TK1541 5cedce35069bf8bf818aa1e07f10792d 255 ProSitePatterns PS00939 Ribosomal protein L1e signature. 106 132 - T 31-10-2018 IPR013000 Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1541 5cedce35069bf8bf818aa1e07f10792d 255 SUPERFAMILY SSF52166 1 252 5.1E-73 T 31-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 TK1541 5cedce35069bf8bf818aa1e07f10792d 255 Hamap MF_01328_A 50S ribosomal protein L4 [rplD]. 2 253 44.531 T 31-10-2018 IPR019970 Ribosomal protein L4 GO:0003735|GO:0005840|GO:0006412|GO:0019843 TK1541 5cedce35069bf8bf818aa1e07f10792d 255 Pfam PF00573 Ribosomal protein L4/L1 family 16 252 1.4E-49 T 31-10-2018 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 TK1541 5cedce35069bf8bf818aa1e07f10792d 255 Gene3D G3DSA:3.40.1370.10 1 255 2.4E-98 T 31-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 TK1541 5cedce35069bf8bf818aa1e07f10792d 255 TIGRFAM TIGR03672 rpl4p_arch: 50S ribosomal protein uL4 1 252 2.1E-116 T 31-10-2018 IPR019970 Ribosomal protein L4 GO:0003735|GO:0005840|GO:0006412|GO:0019843 TK0422 079229a1389d4f902f68f919987f5368 370 Gene3D G3DSA:3.40.1280.30 90 234 3.2E-8 T 31-10-2018 IPR038459 tRNA methyltransferase TRM10-type domain superfamily TK0422 079229a1389d4f902f68f919987f5368 370 Pfam PF04252 Predicted SAM-dependent RNA methyltransferase 175 215 6.6E-5 T 31-10-2018 IPR007364 RNA methyltransferase TK0422/Sfm1 GO:0008168 TK0422 079229a1389d4f902f68f919987f5368 370 PIRSF PIRSF018978 1 370 2.9E-191 T 31-10-2018 IPR016742 tRNA methyltransferase, archaea GO:0008175|GO:0030488 TK0954 a268d219115b0a110e9dc0a6f5b430f2 188 Gene3D G3DSA:3.90.950.10 1 182 1.0E-65 T 31-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like TK0954 a268d219115b0a110e9dc0a6f5b430f2 188 Hamap MF_00528 Septum formation protein Maf [maf]. 1 185 30.98 T 31-10-2018 IPR003697 Maf-like protein GO:0047429 TK0954 a268d219115b0a110e9dc0a6f5b430f2 188 TIGRFAM TIGR00172 maf: septum formation protein Maf 2 177 1.7E-50 T 31-10-2018 IPR003697 Maf-like protein GO:0047429 TK0954 a268d219115b0a110e9dc0a6f5b430f2 188 Pfam PF02545 Maf-like protein 2 176 1.3E-55 T 31-10-2018 IPR003697 Maf-like protein GO:0047429 TK0954 a268d219115b0a110e9dc0a6f5b430f2 188 PIRSF PIRSF006305 1 186 2.0E-59 T 31-10-2018 IPR003697 Maf-like protein GO:0047429 TK0954 a268d219115b0a110e9dc0a6f5b430f2 188 SUPERFAMILY SSF52972 1 177 6.54E-58 T 31-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like TK2242 898b51381375ae0bcf5816bbefe1b110 318 SUPERFAMILY SSF54211 3 140 9.11E-14 T 31-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TK2242 898b51381375ae0bcf5816bbefe1b110 318 PIRSF PIRSF004884 1 318 4.1E-73 T 31-10-2018 IPR004422 GHMP kinase group 1 KEGG: 00790+2.4.2.54|MetaCyc: PWY-6148 TK2242 898b51381375ae0bcf5816bbefe1b110 318 TIGRFAM TIGR00144 beta_RFAP_syn: beta-ribofuranosylaminobenzene 5'-phosphate synthase family 5 315 2.2E-39 T 31-10-2018 IPR004422 GHMP kinase group 1 KEGG: 00790+2.4.2.54|MetaCyc: PWY-6148 TK2242 898b51381375ae0bcf5816bbefe1b110 318 Gene3D G3DSA:3.30.230.10 2 138 3.5E-6 T 31-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TK0527 dc0a070c7ef370be134a8b86467048ea 117 SUPERFAMILY SSF117916 16 59 1.63E-5 T 31-10-2018 IPR034904 Fe-S cluster assembly domain superfamily TK0527 dc0a070c7ef370be134a8b86467048ea 117 Pfam PF01883 Iron-sulfur cluster assembly protein 15 54 6.3E-6 T 31-10-2018 IPR002744 MIP18 family-like TK1190 a22d543d41a1441d7ae55bec94e8f496 358 SUPERFAMILY SSF52540 168 353 3.18E-44 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK1190 a22d543d41a1441d7ae55bec94e8f496 358 Gene3D G3DSA:1.20.120.1190 1 161 4.4E-56 T 31-10-2018 TK1190 a22d543d41a1441d7ae55bec94e8f496 358 Gene3D G3DSA:3.40.50.300 162 357 3.5E-59 T 31-10-2018 TK1190 a22d543d41a1441d7ae55bec94e8f496 358 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 218 233 1.2E-13 T 31-10-2018 IPR006073 GTP binding domain GO:0005525 TK1190 a22d543d41a1441d7ae55bec94e8f496 358 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 170 190 1.2E-13 T 31-10-2018 IPR006073 GTP binding domain GO:0005525 TK1190 a22d543d41a1441d7ae55bec94e8f496 358 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 191 209 1.2E-13 T 31-10-2018 IPR006073 GTP binding domain GO:0005525 TK1190 a22d543d41a1441d7ae55bec94e8f496 358 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 169 328 8.6E-18 T 31-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 TK1190 a22d543d41a1441d7ae55bec94e8f496 358 Pfam PF06858 Nucleolar GTP-binding protein 1 (NOG1) 234 291 4.8E-24 T 31-10-2018 IPR010674 Nucleolar GTP-binding protein 1, Rossman-fold domain GO:0005525 TK1745 2dc18cac17dd9b97176b0394373e606e 275 Pfam PF00892 EamA-like transporter family 139 269 1.1E-19 T 31-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TK1745 2dc18cac17dd9b97176b0394373e606e 275 Pfam PF00892 EamA-like transporter family 3 131 5.3E-22 T 31-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TK1745 2dc18cac17dd9b97176b0394373e606e 275 SUPERFAMILY SSF103481 176 269 6.02E-15 T 31-10-2018 TK1745 2dc18cac17dd9b97176b0394373e606e 275 SUPERFAMILY SSF103481 39 134 2.62E-11 T 31-10-2018 TK0038 0df429e2152b21c4754bcd7e5d1f58d9 294 TIGRFAM TIGR02537 arch_flag_Nterm: archaeal flagellin N-terminal-like domain 6 29 6.1E-6 T 31-10-2018 IPR013373 Flagellin/pilin, N-terminal TK0038 0df429e2152b21c4754bcd7e5d1f58d9 294 Pfam PF01917 Archaebacterial flagellin 8 280 2.3E-45 T 31-10-2018 IPR002774 Flagellin, archaea GO:0005198|GO:0006928 TK2121 837bf4974a7811d1e5bec629b98b93cc 175 Gene3D G3DSA:3.30.930.10 2 173 4.5E-61 T 31-10-2018 TK2121 837bf4974a7811d1e5bec629b98b93cc 175 SUPERFAMILY SSF142913 6 173 3.92E-60 T 31-10-2018 TK2121 837bf4974a7811d1e5bec629b98b93cc 175 Pfam PF11447 Protein of unknown function (DUF3201) 12 162 6.2E-80 T 31-10-2018 IPR024505 Protein of unknown function DUF3201 TK1398 506a300a8b3d4088fec6782060e61425 230 SUPERFAMILY SSF51695 2 222 1.88E-33 T 31-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 TK1398 506a300a8b3d4088fec6782060e61425 230 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 6 75 1.2E-13 T 31-10-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 TK1398 506a300a8b3d4088fec6782060e61425 230 Gene3D G3DSA:3.20.20.190 1 229 1.7E-35 T 31-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 TK1483 d24f6fec92febd01dd5425a68c778025 434 Gene3D G3DSA:1.25.40.10 64 179 5.8E-11 T 31-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TK1483 d24f6fec92febd01dd5425a68c778025 434 Gene3D G3DSA:1.25.40.10 285 411 2.3E-9 T 31-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TK1028 b58c73ba97fa015a5839f7e8dcde2294 67 SUPERFAMILY SSF141694 1 40 3.14E-11 T 31-10-2018 TK1028 b58c73ba97fa015a5839f7e8dcde2294 67 Gene3D G3DSA:4.10.1150.10 1 65 2.7E-10 T 31-10-2018 IPR024069 AF2212-like domain superfamily TK1028 b58c73ba97fa015a5839f7e8dcde2294 67 Pfam PF01954 Protein of unknown function DUF104 1 55 4.2E-17 T 31-10-2018 IPR008203 Uncharacterised protein family UPF0165 TK0971 44c2270e97d8d93af19b3ddfdbaab86f 364 Pfam PF01988 VIT family 148 353 1.6E-45 T 31-10-2018 IPR008217 Ccc1 family TK0971 44c2270e97d8d93af19b3ddfdbaab86f 364 Gene3D G3DSA:1.20.1260.10 2 143 3.5E-9 T 31-10-2018 IPR012347 Ferritin-like TK0971 44c2270e97d8d93af19b3ddfdbaab86f 364 Pfam PF02915 Rubrerythrin 12 139 9.0E-9 T 31-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 TK0971 44c2270e97d8d93af19b3ddfdbaab86f 364 SUPERFAMILY SSF47240 4 139 5.27E-15 T 31-10-2018 IPR009078 Ferritin-like superfamily TK0626 240bb4329203685d51e844d7b166a278 135 SUPERFAMILY SSF55021 57 130 5.09E-12 T 31-10-2018 TK0626 240bb4329203685d51e844d7b166a278 135 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 65 126 0.007 T 31-10-2018 TK0626 240bb4329203685d51e844d7b166a278 135 Pfam PF01842 ACT domain 59 118 9.9E-11 T 31-10-2018 IPR002912 ACT domain TK0626 240bb4329203685d51e844d7b166a278 135 Gene3D G3DSA:3.30.70.260 54 134 6.6E-10 T 31-10-2018 TK2224 15ca5a9f6d20e6482d9be3d3edb30c07 338 Pfam PF05763 Protein of unknown function (DUF835) 135 266 5.0E-38 T 31-10-2018 IPR008553 Domain of unknown function DUF835 TK0719 8ed4ab2d20286959a457c2a4b5da8c86 351 Pfam PF00005 ABC transporter 18 160 4.5E-32 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TK0719 8ed4ab2d20286959a457c2a4b5da8c86 351 Gene3D G3DSA:2.40.50.100 274 345 2.4E-28 T 31-10-2018 TK0719 8ed4ab2d20286959a457c2a4b5da8c86 351 SUPERFAMILY SSF50331 235 350 2.69E-24 T 31-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal TK0719 8ed4ab2d20286959a457c2a4b5da8c86 351 Gene3D G3DSA:2.40.50.140 237 349 2.4E-28 T 31-10-2018 TK0719 8ed4ab2d20286959a457c2a4b5da8c86 351 Pfam PF03459 TOBE domain 288 348 7.2E-10 T 31-10-2018 IPR005116 Transport-associated OB, type 1 TK0719 8ed4ab2d20286959a457c2a4b5da8c86 351 SUPERFAMILY SSF52540 3 234 4.18E-77 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK0719 8ed4ab2d20286959a457c2a4b5da8c86 351 SMART SM00382 27 218 1.6E-12 T 31-10-2018 IPR003593 AAA+ ATPase domain TK0719 8ed4ab2d20286959a457c2a4b5da8c86 351 Gene3D G3DSA:3.40.50.300 2 236 7.6E-74 T 31-10-2018 TK2112 6599c58073487aaf496ef52b42c9c0c4 162 Pfam PF04008 Adenosine specific kinase 7 159 1.6E-62 T 31-10-2018 IPR007153 Adenosine specific kinase TK2112 6599c58073487aaf496ef52b42c9c0c4 162 SUPERFAMILY SSF103165 2 160 2.75E-60 T 31-10-2018 IPR036902 Ta1353-like superfamily TK2112 6599c58073487aaf496ef52b42c9c0c4 162 Gene3D G3DSA:3.40.1520.10 1 162 1.7E-72 T 31-10-2018 IPR036902 Ta1353-like superfamily TK0641 a20724c85a2e557ac66e504022c4b5f3 341 SUPERFAMILY SSF46785 248 335 9.73E-5 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TK0641 a20724c85a2e557ac66e504022c4b5f3 341 Pfam PF04283 Chemotaxis signal transduction system protein F from archaea 13 227 5.9E-14 T 31-10-2018 IPR007381 Chemotaxis signal transduction system protein F TK0641 a20724c85a2e557ac66e504022c4b5f3 341 Gene3D G3DSA:1.10.10.10 245 340 2.9E-6 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TK1487 bd159d471945903c2567afb15c4f3ab2 79 SUPERFAMILY SSF54909 2 75 4.18E-16 T 31-10-2018 IPR011008 Dimeric alpha-beta barrel TK1487 bd159d471945903c2567afb15c4f3ab2 79 Pfam PF01037 Lrp/AsnC ligand binding domain 6 74 2.0E-16 T 31-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain TK1487 bd159d471945903c2567afb15c4f3ab2 79 Gene3D G3DSA:3.30.70.920 1 74 3.6E-22 T 31-10-2018 TK1623 32d158cc3e237c35c14d508f6ee2d4a0 128 TIGRFAM TIGR01195 oadG_fam: sodium pump decarboxylases, gamma subunit 5 87 1.9E-13 T 31-10-2018 IPR005899 Sodium ion-translocating decarboxylase GO:0008948|GO:0015081|GO:0016020|GO:0036376 KEGG: 00620+4.1.1.3 TK1623 32d158cc3e237c35c14d508f6ee2d4a0 128 PIRSF PIRSF018867 3 125 1.1E-28 T 31-10-2018 IPR014497 Methylmalonyl-CoA decarboxylase, delta subunit TK1623 32d158cc3e237c35c14d508f6ee2d4a0 128 Pfam PF04277 Oxaloacetate decarboxylase, gamma chain 8 86 3.9E-15 T 31-10-2018 IPR005899 Sodium ion-translocating decarboxylase GO:0008948|GO:0015081|GO:0016020|GO:0036376 KEGG: 00620+4.1.1.3 TK0130 6f5c4babea1161ce31a16da02d3c70d3 280 SUPERFAMILY SSF52096 65 240 1.27E-28 T 31-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TK0130 6f5c4babea1161ce31a16da02d3c70d3 280 Gene3D G3DSA:3.90.226.10 51 267 5.0E-24 T 31-10-2018 TK0130 6f5c4babea1161ce31a16da02d3c70d3 280 Pfam PF01972 Serine dehydrogenase proteinase 2 277 1.1E-154 T 31-10-2018 IPR002825 Peptidase S49, serine-peptidase prokaryotes GO:0016021 TK0402 b2a0db20ac88433462dc374e46d64210 124 Gene3D G3DSA:2.10.260.10 12 103 6.4E-22 T 31-10-2018 TK0402 b2a0db20ac88433462dc374e46d64210 124 SUPERFAMILY SSF89447 62 96 2.09E-5 T 31-10-2018 IPR037914 SpoVT-AbrB domain superfamily TK0402 b2a0db20ac88433462dc374e46d64210 124 PIRSF PIRSF019240 5 124 2.0E-39 T 31-10-2018 IPR016752 Uncharacterised conserved protein UCP019240, SpoVT/AbrB-related TK1286 a90a6886745b41cb68ab04e3ab4bd6ba 388 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 106 124 3.7E-28 T 31-10-2018 IPR006073 GTP binding domain GO:0005525 TK1286 a90a6886745b41cb68ab04e3ab4bd6ba 388 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 150 168 3.7E-28 T 31-10-2018 IPR006073 GTP binding domain GO:0005525 TK1286 a90a6886745b41cb68ab04e3ab4bd6ba 388 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 85 105 3.7E-28 T 31-10-2018 IPR006073 GTP binding domain GO:0005525 TK1286 a90a6886745b41cb68ab04e3ab4bd6ba 388 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 133 148 3.7E-28 T 31-10-2018 IPR006073 GTP binding domain GO:0005525 TK1286 a90a6886745b41cb68ab04e3ab4bd6ba 388 SUPERFAMILY SSF52540 84 323 1.41E-51 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK1286 a90a6886745b41cb68ab04e3ab4bd6ba 388 SUPERFAMILY SSF81271 309 386 5.76E-19 T 31-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 TK1286 a90a6886745b41cb68ab04e3ab4bd6ba 388 Pfam PF01926 50S ribosome-binding GTPase 84 185 9.5E-22 T 31-10-2018 IPR006073 GTP binding domain GO:0005525 TK1286 a90a6886745b41cb68ab04e3ab4bd6ba 388 Gene3D G3DSA:3.10.20.30 312 388 2.3E-29 T 31-10-2018 IPR012675 Beta-grasp domain superfamily TK1286 a90a6886745b41cb68ab04e3ab4bd6ba 388 Pfam PF16897 C-terminal region of MMR_HSR1 domain 206 310 3.4E-19 T 31-10-2018 IPR031662 GTP binding protein, second domain TK1286 a90a6886745b41cb68ab04e3ab4bd6ba 388 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 83 190 1.6E-13 T 31-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 TK1286 a90a6886745b41cb68ab04e3ab4bd6ba 388 Pfam PF02824 TGS domain 315 386 4.5E-24 T 31-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 TK2017 1de2b6cdee4704a7655ba73b0ffc0b02 139 Pfam PF02566 OsmC-like protein 35 129 4.5E-20 T 31-10-2018 IPR003718 OsmC/Ohr family TK2017 1de2b6cdee4704a7655ba73b0ffc0b02 139 Gene3D G3DSA:3.30.300.20 1 122 1.0E-26 T 31-10-2018 IPR015946 K homology domain-like, alpha/beta TK2017 1de2b6cdee4704a7655ba73b0ffc0b02 139 SUPERFAMILY SSF82784 2 124 1.7E-29 T 31-10-2018 IPR036102 OsmC/Ohr superfamily TK0479 ee43ada64e59c07bf518100453b2b8c4 270 Pfam PF14336 Domain of unknown function (DUF4392) 107 260 4.4E-50 T 31-10-2018 IPR025504 Domain of unknown function DUF4392 KEGG: 00471+4.2.1.48 TK0479 ee43ada64e59c07bf518100453b2b8c4 270 Pfam PF14336 Domain of unknown function (DUF4392) 3 84 9.1E-13 T 31-10-2018 IPR025504 Domain of unknown function DUF4392 KEGG: 00471+4.2.1.48 TK0479 ee43ada64e59c07bf518100453b2b8c4 270 Gene3D G3DSA:3.90.1640.20 1 269 2.6E-97 T 31-10-2018 TK1035 6efcfb5034c51f7148ef45f479e2affd 267 Gene3D G3DSA:3.60.20.10 1 258 1.1E-19 T 31-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TK1035 6efcfb5034c51f7148ef45f479e2affd 267 SUPERFAMILY SSF56235 2 259 1.43E-20 T 31-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TK1035 6efcfb5034c51f7148ef45f479e2affd 267 Pfam PF13230 Glutamine amidotransferases class-II 31 158 1.8E-8 T 31-10-2018 IPR026869 Putative glutamine amidotransferase type 2 TK2257 d8295738cddc3fc57fb59204644daa38 178 PIRSF PIRSF006019 13 169 9.1E-57 T 31-10-2018 IPR016473 Deoxycytidylate deaminase GO:0004132|GO:0006220|GO:0008270 KEGG: 00240+3.5.4.12|MetaCyc: PWY-7210|Reactome: R-HSA-499943 TK2257 d8295738cddc3fc57fb59204644daa38 178 SUPERFAMILY SSF53927 23 144 3.35E-40 T 31-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 TK2257 d8295738cddc3fc57fb59204644daa38 178 Gene3D G3DSA:3.40.140.10 19 168 1.2E-48 T 31-10-2018 TK2257 d8295738cddc3fc57fb59204644daa38 178 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 87 122 - T 31-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 TK2257 d8295738cddc3fc57fb59204644daa38 178 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 22 133 3.4E-29 T 31-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain TK1104 0b462020f8b7ef540dad5ad428d8c1a7 82 ProDom PD486863 PRECURSOR CBIM SIGNAL COBALT MEMBRANE VITAMIN B12 BIOSYNTHESIS COBALAMIN ABC-TYPE 21 81 0.002 T 31-10-2018 TK1227 1b0a8cfe723f3d4394b8a4c54ab50f3d 166 Pfam PF01842 ACT domain 105 158 6.4E-7 T 31-10-2018 IPR002912 ACT domain TK1227 1b0a8cfe723f3d4394b8a4c54ab50f3d 166 SUPERFAMILY SSF55021 105 164 1.22E-8 T 31-10-2018 TK1227 1b0a8cfe723f3d4394b8a4c54ab50f3d 166 Gene3D G3DSA:3.30.70.260 104 165 5.2E-5 T 31-10-2018 TK1227 1b0a8cfe723f3d4394b8a4c54ab50f3d 166 PIRSF PIRSF004897 1 166 3.4E-70 T 31-10-2018 IPR014424 Uncharacterised conserved protein UCP004897, ACT- type TK0312 5021bc276903880fe1b570fded470340 357 Gene3D G3DSA:1.10.3210.10 1 270 4.3E-76 T 31-10-2018 TK0312 5021bc276903880fe1b570fded470340 357 SUPERFAMILY SSF109604 1 342 4.63E-84 T 31-10-2018 TK0312 5021bc276903880fe1b570fded470340 357 SMART SM00471 46 156 7.2E-14 T 31-10-2018 IPR003607 HD/PDEase domain TK0312 5021bc276903880fe1b570fded470340 357 Pfam PF01966 HD domain 50 115 2.4E-8 T 31-10-2018 IPR006674 HD domain TK0995 01dce719e69bfabff4a9bbaf71827ffe 94 Pfam PF01883 Iron-sulfur cluster assembly protein 4 45 2.8E-7 T 31-10-2018 IPR002744 MIP18 family-like TK0995 01dce719e69bfabff4a9bbaf71827ffe 94 Gene3D G3DSA:3.30.300.130 2 85 4.9E-9 T 31-10-2018 IPR034904 Fe-S cluster assembly domain superfamily TK0995 01dce719e69bfabff4a9bbaf71827ffe 94 SUPERFAMILY SSF117916 2 77 1.73E-10 T 31-10-2018 IPR034904 Fe-S cluster assembly domain superfamily TK1407 ebb2058f689236d1185c6fc7796c1a3b 436 SUPERFAMILY SSF161070 11 418 7.98E-12 T 31-10-2018 IPR037272 Sodium:neurotransmitter symporter superfamily GO:0005328 TK1488 ec513a9fa706a9f8690aaf083af8168e 173 Pfam PF03692 Putative zinc- or iron-chelating domain 24 129 7.6E-19 T 31-10-2018 IPR005358 Putative zinc- or iron-chelating domain containing protein TK1629 b38a63044ae5591c719f8b749a79046b 174 SMART SM01022 5 125 6.2E-7 T 31-10-2018 IPR007374 ASCH domain TK1629 b38a63044ae5591c719f8b749a79046b 174 Pfam PF04266 ASCH domain 6 95 2.5E-7 T 31-10-2018 IPR007374 ASCH domain TK1629 b38a63044ae5591c719f8b749a79046b 174 SUPERFAMILY SSF88697 3 143 3.48E-16 T 31-10-2018 IPR015947 PUA-like superfamily TK1093 fc2f084c44064215fe0bb40831b53086 67 Pfam PF02597 ThiS family 10 67 4.4E-10 T 31-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 TK1093 fc2f084c44064215fe0bb40831b53086 67 Gene3D G3DSA:3.10.20.30 1 67 6.8E-24 T 31-10-2018 IPR012675 Beta-grasp domain superfamily TK1093 fc2f084c44064215fe0bb40831b53086 67 SUPERFAMILY SSF54285 4 67 1.21E-11 T 31-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp TK0365 bfa4a7581fd0d7c91574c58741c68b15 243 SUPERFAMILY SSF48317 32 197 1.77E-7 T 31-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily TK0365 bfa4a7581fd0d7c91574c58741c68b15 243 Pfam PF14378 PAP2 superfamily 36 186 6.3E-11 T 31-10-2018 IPR026841 Inositolphosphotransferase Aur1/Ipt1 TK0365 bfa4a7581fd0d7c91574c58741c68b15 243 Gene3D G3DSA:1.20.144.10 105 207 3.3E-6 T 31-10-2018 TK0234 542cadf2546ab651c4a62d180caae412 206 Gene3D G3DSA:3.40.50.150 34 183 3.5E-28 T 31-10-2018 TK0234 542cadf2546ab651c4a62d180caae412 206 Pfam PF13847 Methyltransferase domain 59 174 9.8E-22 T 31-10-2018 IPR025714 Methyltransferase domain TK0234 542cadf2546ab651c4a62d180caae412 206 SUPERFAMILY SSF53335 20 177 2.3E-28 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TK2179 a53a4c62fe2cc533a45f44c3951d9934 261 PIRSF PIRSF005956 1 259 1.5E-97 T 31-10-2018 IPR005137 Membrane complex biogenesis protein, BtpA family TK2179 a53a4c62fe2cc533a45f44c3951d9934 261 Pfam PF03437 BtpA family 5 254 5.8E-107 T 31-10-2018 IPR005137 Membrane complex biogenesis protein, BtpA family TK2179 a53a4c62fe2cc533a45f44c3951d9934 261 SUPERFAMILY SSF51366 20 251 3.53E-27 T 31-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 TK2179 a53a4c62fe2cc533a45f44c3951d9934 261 TIGRFAM TIGR00259 thylakoid_BtpA: membrane complex biogenesis protein, BtpA family 6 256 3.1E-109 T 31-10-2018 IPR005137 Membrane complex biogenesis protein, BtpA family TK2179 a53a4c62fe2cc533a45f44c3951d9934 261 ProDom PD011184 BTPA I PHOTOSYSTEM BIOGENESIS ASSEMBLY SGCQ TRIPHOSPHATASE NUCLEOSIDE PAE3553 ENZYME 28 199 4.0E-92 T 31-10-2018 IPR005137 Membrane complex biogenesis protein, BtpA family TK0788 5ca4e4dbf8d5102d51a6f2deee67b416 269 Pfam PF01889 Membrane protein of unknown function DUF63 3 268 2.6E-88 T 31-10-2018 IPR002749 Protein of unknown function DUF63 TK0906 afa8b3df5b97ac9bebb318df85a4a387 197 Gene3D G3DSA:3.30.2170.10 143 188 2.0E-7 T 31-10-2018 TK0906 afa8b3df5b97ac9bebb318df85a4a387 197 Gene3D G3DSA:3.30.2170.10 2 142 8.9E-40 T 31-10-2018 TK0906 afa8b3df5b97ac9bebb318df85a4a387 197 Pfam PF04493 Endonuclease V 15 137 1.5E-34 T 31-10-2018 IPR007581 Endonuclease V GO:0004519|GO:0006281 TK0906 afa8b3df5b97ac9bebb318df85a4a387 197 Pfam PF04493 Endonuclease V 145 181 2.5E-5 T 31-10-2018 IPR007581 Endonuclease V GO:0004519|GO:0006281 TK0906 afa8b3df5b97ac9bebb318df85a4a387 197 Hamap MF_00801 Endonuclease V [nfi]. 5 190 26.855 T 31-10-2018 IPR007581 Endonuclease V GO:0004519|GO:0006281 TK0945 26b8ffba7e4205db08537cbf0a25ebaa 234 Pfam PF01909 Nucleotidyltransferase domain 32 122 3.8E-8 T 31-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 TK0945 26b8ffba7e4205db08537cbf0a25ebaa 234 SUPERFAMILY SSF81301 20 71 1.9E-9 T 31-10-2018 TK0945 26b8ffba7e4205db08537cbf0a25ebaa 234 PIRSF PIRSF005928 10 232 6.2E-102 T 31-10-2018 IPR009185 Predicted nucleotidyltransferase TK0945 26b8ffba7e4205db08537cbf0a25ebaa 234 Gene3D G3DSA:3.30.460.10 21 93 1.9E-7 T 31-10-2018 TK1890 4a79cc4183ddaf64f0764aceb2c21953 180 SMART SM00506 3 146 1.3E-51 T 31-10-2018 IPR002589 Macro domain TK1890 4a79cc4183ddaf64f0764aceb2c21953 180 Pfam PF01661 Macro domain 20 145 1.9E-34 T 31-10-2018 IPR002589 Macro domain TK1890 4a79cc4183ddaf64f0764aceb2c21953 180 SUPERFAMILY SSF52949 4 178 5.05E-50 T 31-10-2018 TK1890 4a79cc4183ddaf64f0764aceb2c21953 180 Gene3D G3DSA:3.40.220.10 1 180 6.0E-55 T 31-10-2018 TK0319 1ffe8d32a71b07341fb054cfd4c3b138 510 SUPERFAMILY SSF51717 162 384 1.31E-25 T 31-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TK0319 1ffe8d32a71b07341fb054cfd4c3b138 510 TIGRFAM TIGR00284 TIGR00284: dihydropteroate synthase-related protein 4 502 5.7E-98 T 31-10-2018 IPR005236 Dihydropteroate synthase-related protein synthase-related protein TK2054 554f05e67fd769d15f5ad8886e7678b4 306 Pfam PF12679 ABC-2 family transporter protein 3 305 3.8E-60 T 31-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 TK2187 4c91df492ddc2b0630623179d23333d9 352 Pfam PF05763 Protein of unknown function (DUF835) 227 350 1.3E-36 T 31-10-2018 IPR008553 Domain of unknown function DUF835 TK1401 b5786d41676fad25296ed8cde15e4dec 292 Gene3D G3DSA:3.40.50.1820 44 291 1.2E-44 T 31-10-2018 IPR029058 Alpha/Beta hydrolase fold TK1401 b5786d41676fad25296ed8cde15e4dec 292 SUPERFAMILY SSF53474 12 290 1.15E-53 T 31-10-2018 IPR029058 Alpha/Beta hydrolase fold TK1401 b5786d41676fad25296ed8cde15e4dec 292 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 83 162 1.6E-13 T 31-10-2018 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 TK0863 d16c60ba65c56aa565901045eb23dbe9 294 Hamap MF_00024 Cobalamin biosynthesis protein CbiB [cbiB]. 1 292 78.01 T 31-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 TK0863 d16c60ba65c56aa565901045eb23dbe9 294 Pfam PF03186 CobD/Cbib protein 8 268 5.6E-84 T 31-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 TK0863 d16c60ba65c56aa565901045eb23dbe9 294 TIGRFAM TIGR00380 cobD: cobalamin biosynthesis protein CobD 7 286 1.1E-82 T 31-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 TK1010 d7516bbc69a7ccb91651a906e2039eb4 467 Pfam PF10117 McrBC 5-methylcytosine restriction system component 57 385 9.3E-82 T 31-10-2018 IPR019292 5-methylcytosine restriction system component TK0661 f94eabc222427e7a0e8607516b7090a2 333 Gene3D G3DSA:3.40.50.1980 27 189 1.5E-26 T 31-10-2018 TK0661 f94eabc222427e7a0e8607516b7090a2 333 Pfam PF01297 Zinc-uptake complex component A periplasmic 31 287 1.4E-33 T 31-10-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 TK0661 f94eabc222427e7a0e8607516b7090a2 333 SUPERFAMILY SSF53807 27 290 5.4E-45 T 31-10-2018 TK1959 a04e8a0863d63cfce1b9d37f9e661fd9 268 Pfam PF01336 OB-fold nucleic acid binding domain 45 112 2.3E-8 T 31-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 TK1959 a04e8a0863d63cfce1b9d37f9e661fd9 268 Gene3D G3DSA:2.40.50.140 8 138 5.2E-13 T 31-10-2018 TK1959 a04e8a0863d63cfce1b9d37f9e661fd9 268 SUPERFAMILY SSF50249 33 131 2.63E-11 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold TK2290 2d05078c48f83df48087452cd135daf3 444 TIGRFAM TIGR03326 rubisco_III: ribulose bisphosphate carboxylase, type III 11 438 2.9E-226 T 31-10-2018 IPR017712 Ribulose bisphosphate carboxylase, type III GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 TK2290 2d05078c48f83df48087452cd135daf3 444 Gene3D G3DSA:3.20.20.110 137 438 2.7E-127 T 31-10-2018 IPR036376 Ribulose bisphosphate carboxylase, large subunit, C-terminal domain superfamily GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 TK2290 2d05078c48f83df48087452cd135daf3 444 Hamap MF_01133 Ribulose bisphosphate carboxylase [rbcL]. 10 439 52.998 T 31-10-2018 IPR017712 Ribulose bisphosphate carboxylase, type III GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 TK2290 2d05078c48f83df48087452cd135daf3 444 SUPERFAMILY SSF51649 136 441 6.02E-107 T 31-10-2018 IPR036376 Ribulose bisphosphate carboxylase, large subunit, C-terminal domain superfamily GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 TK2290 2d05078c48f83df48087452cd135daf3 444 Pfam PF00016 Ribulose bisphosphate carboxylase large chain, catalytic domain 142 438 7.0E-95 T 31-10-2018 IPR000685 Ribulose bisphosphate carboxylase, large subunit, C-terminal GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 TK2290 2d05078c48f83df48087452cd135daf3 444 Pfam PF02788 Ribulose bisphosphate carboxylase large chain, N-terminal domain 12 131 3.5E-46 T 31-10-2018 IPR017443 Ribulose bisphosphate carboxylase, large subunit, ferrodoxin-like N-terminal GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 TK2290 2d05078c48f83df48087452cd135daf3 444 Gene3D G3DSA:3.30.70.150 1 136 4.5E-48 T 31-10-2018 IPR036422 RuBisCO large subunit, N-terminal domain superfamily GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 TK2290 2d05078c48f83df48087452cd135daf3 444 SUPERFAMILY SSF54966 3 137 2.49E-40 T 31-10-2018 IPR036422 RuBisCO large subunit, N-terminal domain superfamily GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 TK0060 519a3442cc140fa0643cc1d874117711 180 Hamap MF_00077 tRNA (cytidine(56)-2'-O)-methyltransferase. 4 179 44.605 T 31-10-2018 IPR002845 tRNA ribose 2'-O-methyltransferase, aTrm56 GO:0002128|GO:0005737|GO:0008175 TK0060 519a3442cc140fa0643cc1d874117711 180 PIRSF PIRSF016123 2 180 6.2E-87 T 31-10-2018 IPR002845 tRNA ribose 2'-O-methyltransferase, aTrm56 GO:0002128|GO:0005737|GO:0008175 TK0060 519a3442cc140fa0643cc1d874117711 180 ProDom PD016584 UPF0106 MK0803 MM0086 METAL MA3241 UNCHARACTERIZED DOMAIN TA0931 APE2006 ST0333 57 180 2.0E-67 T 31-10-2018 IPR002845 tRNA ribose 2'-O-methyltransferase, aTrm56 GO:0002128|GO:0005737|GO:0008175 TK0060 519a3442cc140fa0643cc1d874117711 180 Gene3D G3DSA:3.40.1280.10 4 180 1.2E-81 T 31-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal TK0060 519a3442cc140fa0643cc1d874117711 180 SUPERFAMILY SSF75217 4 177 2.43E-70 T 31-10-2018 IPR029028 Alpha/beta knot methyltransferases TK0060 519a3442cc140fa0643cc1d874117711 180 Pfam PF01994 tRNA ribose 2'-O-methyltransferase, aTrm56 57 176 2.2E-52 T 31-10-2018 IPR002845 tRNA ribose 2'-O-methyltransferase, aTrm56 GO:0002128|GO:0005737|GO:0008175 TK1004 d7ab348fefe9d5f5e680785aa3a74c9c 308 SUPERFAMILY SSF51735 1 306 2.35E-101 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily TK1004 d7ab348fefe9d5f5e680785aa3a74c9c 308 Gene3D G3DSA:3.40.50.720 9 290 1.7E-107 T 31-10-2018 TK1004 d7ab348fefe9d5f5e680785aa3a74c9c 308 Pfam PF01370 NAD dependent epimerase/dehydratase family 7 237 5.5E-62 T 31-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 TK1004 d7ab348fefe9d5f5e680785aa3a74c9c 308 Gene3D G3DSA:3.90.25.10 169 302 1.7E-107 T 31-10-2018 TK1219 e06f1d98aee9cd69da66550d95addb7c 616 Pfam PF00361 Proton-conducting membrane transporter 122 419 6.9E-53 T 31-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TK0815 6b9c3b01b7897a20ab2438c1f857d81c 148 Pfam PF00578 AhpC/TSA family 3 127 5.7E-32 T 31-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 TK0815 6b9c3b01b7897a20ab2438c1f857d81c 148 SUPERFAMILY SSF52833 2 147 1.02E-42 T 31-10-2018 IPR036249 Thioredoxin-like superfamily TK0815 6b9c3b01b7897a20ab2438c1f857d81c 148 Gene3D G3DSA:3.40.30.10 1 148 3.2E-44 T 31-10-2018 TK0815 6b9c3b01b7897a20ab2438c1f857d81c 148 PIRSF PIRSF000239 1 148 8.1E-21 T 31-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 TK2073 90c72f6bd5bce948a8acf1371455fb5e 125 SUPERFAMILY SSF54862 4 109 4.19E-15 T 31-10-2018 TK2073 90c72f6bd5bce948a8acf1371455fb5e 125 Gene3D G3DSA:3.30.70.20 1 58 6.8E-11 T 31-10-2018 TK2073 90c72f6bd5bce948a8acf1371455fb5e 125 Pfam PF12838 4Fe-4S dicluster domain 7 54 6.3E-10 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TK2073 90c72f6bd5bce948a8acf1371455fb5e 125 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 7 18 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TK2117 948fe964ee49ff3815a18f2d3e70e019 232 Pfam PF00899 ThiF family 10 231 3.7E-59 T 31-10-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 TK2117 948fe964ee49ff3815a18f2d3e70e019 232 SUPERFAMILY SSF69572 2 230 1.23E-80 T 31-10-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 TK2117 948fe964ee49ff3815a18f2d3e70e019 232 Gene3D G3DSA:3.40.50.720 2 232 4.6E-75 T 31-10-2018 TK1096 8b57f1b608ad2811535d1fb7f89ab3f1 193 ProDom PD022789 MEMBRANE SURFACE PRECURSOR SIGNAL PROTEIN YBJE TRANSMEMBRANE INNER PREDICTED STY0934 24 193 3.0E-59 T 31-10-2018 IPR005642 Lysine exporter LysO TK1096 8b57f1b608ad2811535d1fb7f89ab3f1 193 Pfam PF03956 Lysine exporter LysO 9 190 2.0E-57 T 31-10-2018 IPR005642 Lysine exporter LysO TK0456 0f8f63486edcc08575e6fdbf5ebc47cf 137 Gene3D G3DSA:3.40.50.1010 3 132 6.8E-16 T 31-10-2018 TK0456 0f8f63486edcc08575e6fdbf5ebc47cf 137 Pfam PF01850 PIN domain 4 126 2.1E-19 T 31-10-2018 IPR002716 PIN domain TK0456 0f8f63486edcc08575e6fdbf5ebc47cf 137 SUPERFAMILY SSF88723 1 127 3.08E-26 T 31-10-2018 IPR029060 PIN-like domain superfamily TK0456 0f8f63486edcc08575e6fdbf5ebc47cf 137 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 3 131 9.67 T 31-10-2018 IPR022907 VapC family GO:0004540 TK0456 0f8f63486edcc08575e6fdbf5ebc47cf 137 SMART SM00670 1 123 5.0E-13 T 31-10-2018 IPR002716 PIN domain TK1589 aafacfcf52575503cae298adbe0bfd43 540 Gene3D G3DSA:2.60.40.1120 291 353 6.6E-5 T 31-10-2018 TK1589 aafacfcf52575503cae298adbe0bfd43 540 Pfam PF08308 PEGA domain 423 489 4.5E-21 T 31-10-2018 IPR013229 PEGA TK1589 aafacfcf52575503cae298adbe0bfd43 540 Pfam PF08308 PEGA domain 283 352 3.8E-9 T 31-10-2018 IPR013229 PEGA TK1589 aafacfcf52575503cae298adbe0bfd43 540 Pfam PF08308 PEGA domain 357 421 3.8E-6 T 31-10-2018 IPR013229 PEGA TK1589 aafacfcf52575503cae298adbe0bfd43 540 Pfam PF08308 PEGA domain 202 269 9.9E-5 T 31-10-2018 IPR013229 PEGA TK0824 024b3bd4879aa9e1a66f99360cc58209 168 Pfam PF02915 Rubrerythrin 30 162 2.7E-17 T 31-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 TK0824 024b3bd4879aa9e1a66f99360cc58209 168 Gene3D G3DSA:1.20.1260.10 18 167 4.6E-30 T 31-10-2018 IPR012347 Ferritin-like TK0824 024b3bd4879aa9e1a66f99360cc58209 168 SUPERFAMILY SSF47240 30 164 3.25E-26 T 31-10-2018 IPR009078 Ferritin-like superfamily TK0250 b682877cb682f6a0895a863988afe776 336 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 1 331 52.083 T 31-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 TK0250 b682877cb682f6a0895a863988afe776 336 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 3 329 1.3E-92 T 31-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 TK0250 b682877cb682f6a0895a863988afe776 336 Gene3D G3DSA:3.90.1150.10 17 327 7.1E-99 T 31-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TK0250 b682877cb682f6a0895a863988afe776 336 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 201 210 - T 31-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 TK0250 b682877cb682f6a0895a863988afe776 336 SUPERFAMILY SSF53383 13 328 1.1E-74 T 31-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TK0250 b682877cb682f6a0895a863988afe776 336 Pfam PF00155 Aminotransferase class I and II 21 315 3.0E-49 T 31-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 TK0250 b682877cb682f6a0895a863988afe776 336 Gene3D G3DSA:3.40.640.10 43 251 7.1E-99 T 31-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TK0044 59dab287ad2fc64c1f0f09000572bdea 474 Pfam PF04659 Archaeal flagella protein 354 446 1.0E-29 T 31-10-2018 IPR006752 Archaeal flagella protein FlaD/E domain GO:0097588 TK0044 59dab287ad2fc64c1f0f09000572bdea 474 ProDom PD012942 FLAGELLUM FLAGELLA-RELATED E D ACCESSORY FLAGELLA ARCHAEAL FLAD SIMILAR D 357 458 5.0E-54 T 31-10-2018 IPR006752 Archaeal flagella protein FlaD/E domain GO:0097588 TK0044 59dab287ad2fc64c1f0f09000572bdea 474 PIRSF PIRSF017066 1 474 4.3E-151 T 31-10-2018 IPR016682 Flagella accessory protein D, predicted, archaeal TK2108 737b66f6e1e1d89918c20708e7db982b 1127 Pfam PF03176 MMPL family 803 1116 5.7E-27 T 31-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 TK2108 737b66f6e1e1d89918c20708e7db982b 1127 Pfam PF03176 MMPL family 551 748 1.6E-36 T 31-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 TK2108 737b66f6e1e1d89918c20708e7db982b 1127 Gene3D G3DSA:1.20.1640.10 527 738 1.4E-8 T 31-10-2018 TK2108 737b66f6e1e1d89918c20708e7db982b 1127 SUPERFAMILY SSF82866 954 1116 8.37E-20 T 31-10-2018 TK2108 737b66f6e1e1d89918c20708e7db982b 1127 SUPERFAMILY SSF82866 533 738 1.96E-26 T 31-10-2018 TK0032 30434c15c2194d7a1477076adfdca25d 500 SUPERFAMILY SSF54826 339 400 1.87E-6 T 31-10-2018 TK0032 30434c15c2194d7a1477076adfdca25d 500 Gene3D G3DSA:1.10.10.10 437 498 3.2E-6 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TK2256 95201ddfcdee4243b433324dee6086af 124 Pfam PF10066 Uncharacterized conserved protein (DUF2304) 4 108 2.5E-26 T 31-10-2018 IPR019277 Protein of unknown function DUF2304 TK0491 b02d27480344fcf4643c1b519e86e3ac 417 SUPERFAMILY SSF101898 79 292 1.83E-9 T 31-10-2018 TK0491 b02d27480344fcf4643c1b519e86e3ac 417 Gene3D G3DSA:2.120.10.30 47 296 2.5E-7 T 31-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like TK0380 fc14c546baa6be4222dc5ad169a14c23 283 Gene3D G3DSA:3.40.50.10880 132 283 1.7E-59 T 31-10-2018 TK0380 fc14c546baa6be4222dc5ad169a14c23 283 Gene3D G3DSA:1.10.285.20 68 131 5.2E-21 T 31-10-2018 TK0380 fc14c546baa6be4222dc5ad169a14c23 283 Pfam PF01937 Protein of unknown function DUF89 4 277 4.0E-58 T 31-10-2018 IPR002791 Domain of unknown function DUF89 TK0380 fc14c546baa6be4222dc5ad169a14c23 283 PIRSF PIRSF006593 1 283 1.2E-101 T 31-10-2018 IPR014444 Uncharacterised conserved protein UCP006593 TK0380 fc14c546baa6be4222dc5ad169a14c23 283 Gene3D G3DSA:1.10.8.380 1 67 7.7E-27 T 31-10-2018 TK0380 fc14c546baa6be4222dc5ad169a14c23 283 SUPERFAMILY SSF111321 1 280 1.22E-83 T 31-10-2018 IPR036075 AF1104-like superfamily TK0292 96f97f9ce5c01ebe080ea004d903c27c 154 Pfam PF01927 Mut7-C RNAse domain 1 144 1.5E-44 T 31-10-2018 IPR002782 Mut7-C RNAse domain TK1892 d6c5e344dfc4e955c70c36b658963a0a 788 SUPERFAMILY SSF54001 491 625 3.27E-9 T 31-10-2018 IPR038765 Papain-like cysteine peptidase superfamily TK1892 d6c5e344dfc4e955c70c36b658963a0a 788 Pfam PF04473 Transglutaminase-like domain 491 648 7.2E-57 T 31-10-2018 IPR007562 Transglutaminase-like domain TK1892 d6c5e344dfc4e955c70c36b658963a0a 788 Gene3D G3DSA:3.10.620.30 452 636 3.7E-8 T 31-10-2018 TK0789 1b22a4521391977e9dd8853aa36fcea2 351 Hamap MF_00497_A Glycerol-1-phosphate dehydrogenase [NAD(P)+] [egsA]. 7 351 46.009 T 31-10-2018 IPR023002 Glycerol-1-phosphate dehydrogenase, archaea GO:0050492|GO:0055114 KEGG: 00564+1.1.1.261|MetaCyc: PWY-6349 TK0789 1b22a4521391977e9dd8853aa36fcea2 351 Pfam PF13685 Iron-containing alcohol dehydrogenase 17 273 1.3E-70 T 31-10-2018 IPR032837 Glycerol-1-phosphate dehydrogenase KEGG: 00564+1.1.1.261|MetaCyc: PWY-6349 TK0789 1b22a4521391977e9dd8853aa36fcea2 351 PIRSF PIRSF000112 1 348 4.7E-68 T 31-10-2018 IPR016205 Glycerol dehydrogenase GO:0016614|GO:0046872|GO:0055114 KEGG: 00564+1.1.1.261|MetaCyc: PWY-6349 TK0789 1b22a4521391977e9dd8853aa36fcea2 351 Gene3D G3DSA:1.20.1090.10 161 350 2.6E-66 T 31-10-2018 TK0789 1b22a4521391977e9dd8853aa36fcea2 351 Gene3D G3DSA:3.40.50.1970 2 160 4.2E-35 T 31-10-2018 TK0789 1b22a4521391977e9dd8853aa36fcea2 351 SUPERFAMILY SSF56796 6 344 9.29E-73 T 31-10-2018 TK1720 4e2dbb282166c2835bc4df73025a1953 241 SUPERFAMILY SSF53448 1 223 7.67E-48 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TK1720 4e2dbb282166c2835bc4df73025a1953 241 Gene3D G3DSA:3.90.550.10 1 237 4.4E-53 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TK1720 4e2dbb282166c2835bc4df73025a1953 241 Pfam PF00535 Glycosyl transferase family 2 5 168 3.2E-34 T 31-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TK2270 6a3e222d69015572e10a03344d498d68 63 Pfam PF01402 Ribbon-helix-helix protein, copG family 7 45 2.1E-8 T 31-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 TK2270 6a3e222d69015572e10a03344d498d68 63 SUPERFAMILY SSF47598 4 46 4.78E-13 T 31-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 TK2270 6a3e222d69015572e10a03344d498d68 63 Gene3D G3DSA:1.10.1220.10 11 46 8.8E-11 T 31-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 TK0737 a5c2a8115ef2e7834a3f3aa759f3fa14 171 Pfam PF05763 Protein of unknown function (DUF835) 41 169 2.4E-33 T 31-10-2018 IPR008553 Domain of unknown function DUF835 TK2042 63911bb0561ddb30796ad48f54e61f46 233 SUPERFAMILY SSF52540 5 230 1.83E-38 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK2042 63911bb0561ddb30796ad48f54e61f46 233 Pfam PF06745 KaiC 9 228 3.0E-52 T 31-10-2018 IPR014774 KaiC-like domain TK2042 63911bb0561ddb30796ad48f54e61f46 233 Gene3D G3DSA:3.40.50.300 3 229 4.3E-55 T 31-10-2018 TK0721 67d9ff9ef7e6c3462014580b3a46f6ee 179 PIRSF PIRSF037213 4 178 1.8E-70 T 31-10-2018 IPR017139 Uncharacterised conserved protein UCP037213 TK0721 67d9ff9ef7e6c3462014580b3a46f6ee 179 Pfam PF10007 Uncharacterized protein conserved in archaea (DUF2250) 16 106 5.4E-34 T 31-10-2018 IPR019254 Protein of unknown function DUF2250 TK1951 00abd7055dd8e54c8ded0ce208236903 125 SMART SM01405 4 124 3.6E-54 T 31-10-2018 IPR001377 Ribosomal protein S6e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-166208|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1951 00abd7055dd8e54c8ded0ce208236903 125 ProSitePatterns PS00578 Ribosomal protein S6e signature. 63 74 - T 31-10-2018 IPR018282 Ribosomal protein S6e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-166208|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1951 00abd7055dd8e54c8ded0ce208236903 125 Pfam PF01092 Ribosomal protein S6e 4 124 2.8E-36 T 31-10-2018 IPR001377 Ribosomal protein S6e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-166208|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1951 00abd7055dd8e54c8ded0ce208236903 125 Hamap MF_00512 30S ribosomal protein S6e [rps6e]. 2 125 18.575 T 31-10-2018 IPR020924 Ribosomal protein S6e, archaeal GO:0003735|GO:0005840|GO:0006412 TK1030 3e30ec7272300baa9d92ea0b40cda975 135 Pfam PF09868 Uncharacterized protein conserved in archaea (DUF2095) 8 135 2.7E-77 T 31-10-2018 IPR018662 Protein of unknown function DUF2095 TK0471 a244302751097847a0a6af71f9843de1 264 Pfam PF11495 Archaeal transcriptional regulator TrmB 125 263 3.0E-5 T 31-10-2018 IPR021586 Transcription regulator TrmB, C-terminal TK0471 a244302751097847a0a6af71f9843de1 264 SUPERFAMILY SSF46785 10 96 4.57E-7 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TK0471 a244302751097847a0a6af71f9843de1 264 Gene3D G3DSA:3.30.870.10 122 264 2.6E-87 T 31-10-2018 TK0471 a244302751097847a0a6af71f9843de1 264 Gene3D G3DSA:1.10.10.10 2 109 3.3E-21 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TK0471 a244302751097847a0a6af71f9843de1 264 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 10 78 8.3E-19 T 31-10-2018 IPR002831 Transcription regulator TrmB, N-terminal TK2077 ed102273baf433c8f8ba55430b38e728 166 SUPERFAMILY SSF54862 1 150 1.05E-52 T 31-10-2018 TK2077 ed102273baf433c8f8ba55430b38e728 166 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 80 91 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TK2077 ed102273baf433c8f8ba55430b38e728 166 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 13 24 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TK2077 ed102273baf433c8f8ba55430b38e728 166 Pfam PF13247 4Fe-4S dicluster domain 42 135 1.0E-25 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TK2077 ed102273baf433c8f8ba55430b38e728 166 Gene3D G3DSA:3.30.70.20 3 45 8.9E-6 T 31-10-2018 TK2077 ed102273baf433c8f8ba55430b38e728 166 Gene3D G3DSA:3.30.70.20 104 162 1.7E-13 T 31-10-2018 TK2077 ed102273baf433c8f8ba55430b38e728 166 Gene3D G3DSA:3.30.70.20 50 103 5.7E-18 T 31-10-2018 TK0989 dc18ce21d4618bc5347252f9b7495ab5 281 Pfam PF01791 DeoC/LacD family aldolase 24 251 6.0E-36 T 31-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 TK0989 dc18ce21d4618bc5347252f9b7495ab5 281 SUPERFAMILY SSF51569 8 266 1.35E-69 T 31-10-2018 TK0989 dc18ce21d4618bc5347252f9b7495ab5 281 PIRSF PIRSF038992 4 281 2.4E-92 T 31-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 TK0989 dc18ce21d4618bc5347252f9b7495ab5 281 SMART SM01133 23 251 2.3E-42 T 31-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 TK0989 dc18ce21d4618bc5347252f9b7495ab5 281 Gene3D G3DSA:3.20.20.70 2 279 1.6E-84 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TK0539 4658f70d01dfc9e76375c81dbfc3ff6a 318 Hamap MF_00584 Putative HTH-type transcriptional regulatory protein . 2 300 28.635 T 31-10-2018 IPR020886 Transcription regulator HTH, Cro/C1-type DNA-binding GO:0003700|GO:0006355 TK0539 4658f70d01dfc9e76375c81dbfc3ff6a 318 Pfam PF01381 Helix-turn-helix 131 183 1.4E-12 T 31-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TK0539 4658f70d01dfc9e76375c81dbfc3ff6a 318 Gene3D G3DSA:1.10.260.40 126 206 3.7E-12 T 31-10-2018 TK0539 4658f70d01dfc9e76375c81dbfc3ff6a 318 SUPERFAMILY SSF47413 126 183 1.26E-12 T 31-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TK0539 4658f70d01dfc9e76375c81dbfc3ff6a 318 SMART SM00530 130 185 9.0E-12 T 31-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TK1270 f8e763703a3e51b269002151d9daab65 69 Pfam PF05239 PRC-barrel domain 2 68 2.6E-12 T 31-10-2018 IPR027275 PRC-barrel domain TK1270 f8e763703a3e51b269002151d9daab65 69 SUPERFAMILY SSF50346 1 66 2.2E-13 T 31-10-2018 IPR011033 PRC-barrel-like superfamily TK1270 f8e763703a3e51b269002151d9daab65 69 Gene3D G3DSA:2.30.30.240 3 69 6.7E-6 T 31-10-2018 TK1858 5b358e047338824f76efb47fa31529e0 648 Pfam PF02687 FtsX-like permease family 230 319 4.4E-9 T 31-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 TK1994 d0c42b9c2a693087e5cdf69fa99c2f0b 108 Gene3D G3DSA:3.30.460.10 3 105 1.8E-18 T 31-10-2018 TK1994 d0c42b9c2a693087e5cdf69fa99c2f0b 108 SUPERFAMILY SSF81301 3 108 1.02E-21 T 31-10-2018 TK1994 d0c42b9c2a693087e5cdf69fa99c2f0b 108 Pfam PF01909 Nucleotidyltransferase domain 18 88 6.2E-13 T 31-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 TK1709 3959e2d4ef4fc3b58c9ce92854155e64 135 Gene3D G3DSA:3.30.460.10 10 97 1.8E-10 T 31-10-2018 TK1709 3959e2d4ef4fc3b58c9ce92854155e64 135 SUPERFAMILY SSF81301 1 107 4.0E-13 T 31-10-2018 TK1330 7c78f5c14b4eb1a7dc5fad81482c7fc7 108 SUPERFAMILY SSF69695 2 106 4.84E-23 T 31-10-2018 IPR036521 Signal recognition particle, subunit SRP19-like superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 TK1330 7c78f5c14b4eb1a7dc5fad81482c7fc7 108 Pfam PF01922 SRP19 protein 4 81 3.5E-12 T 31-10-2018 IPR002778 Signal recognition particle, SRP19 subunit GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 TK1330 7c78f5c14b4eb1a7dc5fad81482c7fc7 108 Hamap MF_00305 Signal recognition particle 19 kDa protein [srp19]. 4 93 22.503 T 31-10-2018 IPR022938 Signal recognition particle, SRP19 subunit, archaeal-type TK1330 7c78f5c14b4eb1a7dc5fad81482c7fc7 108 Gene3D G3DSA:3.30.56.30 1 105 3.5E-32 T 31-10-2018 IPR036521 Signal recognition particle, subunit SRP19-like superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 TK1857 e4b2bf49f2078c1bdfd9a4536a8bdd71 357 Gene3D G3DSA:1.10.1580.10 169 252 3.6E-13 T 31-10-2018 IPR023179 GTP-binding protein, orthogonal bundle domain superfamily TK1857 e4b2bf49f2078c1bdfd9a4536a8bdd71 357 Gene3D G3DSA:3.40.50.300 5 162 8.1E-45 T 31-10-2018 TK1857 e4b2bf49f2078c1bdfd9a4536a8bdd71 357 SUPERFAMILY SSF52540 4 168 8.65E-39 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK1857 e4b2bf49f2078c1bdfd9a4536a8bdd71 357 Pfam PF01926 50S ribosome-binding GTPase 107 162 3.9E-13 T 31-10-2018 IPR006073 GTP binding domain GO:0005525 TK1784 2add434eb5cfd439fe1229f3c18eae67 248 Gene3D G3DSA:3.40.50.150 66 248 1.7E-42 T 31-10-2018 TK1784 2add434eb5cfd439fe1229f3c18eae67 248 Pfam PF13649 Methyltransferase domain 85 158 1.8E-7 T 31-10-2018 TK1784 2add434eb5cfd439fe1229f3c18eae67 248 SUPERFAMILY SSF53335 8 233 4.97E-25 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TK2173 312ca308b481c63a8a2e63bd861ee0f1 193 Pfam PF09851 Short C-terminal domain 163 190 2.9E-11 T 31-10-2018 IPR018649 SHOCT domain TK2173 312ca308b481c63a8a2e63bd861ee0f1 193 Pfam PF14470 Bacterial PH domain 17 109 9.5E-23 T 31-10-2018 IPR039519 YokE-like, PH domain TK2124 bb52cc4bb9189f411dc4887f56015e27 278 SUPERFAMILY SSF111331 2 265 1.11E-72 T 31-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily TK2124 bb52cc4bb9189f411dc4887f56015e27 278 Pfam PF01513 ATP-NAD kinase 2 261 9.3E-71 T 31-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 TK2124 bb52cc4bb9189f411dc4887f56015e27 278 Gene3D G3DSA:3.40.50.10330 20 267 6.4E-71 T 31-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 TK2124 bb52cc4bb9189f411dc4887f56015e27 278 Gene3D G3DSA:2.60.200.30 121 254 6.4E-71 T 31-10-2018 IPR017437 ATP-NAD kinase, PpnK-type, C-terminal GO:0003951|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 TK2124 bb52cc4bb9189f411dc4887f56015e27 278 Hamap MF_00361 NAD kinase [nadK]. 1 276 30.068 T 31-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 TK0325 569b9cacf1a0c173020d2b0c0d2dffea 152 SUPERFAMILY SSF51004 49 110 5.62E-6 T 31-10-2018 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain superfamily TK2016 2516234151dbf1854d51041409c3ad83 129 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 14 103 9.1E-23 T 31-10-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis TK2016 2516234151dbf1854d51041409c3ad83 129 SUPERFAMILY SSF53146 1 109 9.29E-33 T 31-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily TK2016 2516234151dbf1854d51041409c3ad83 129 Gene3D G3DSA:3.30.420.130 1 104 1.1E-31 T 31-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily TK1917 fcde95b45fd8776a8ce1002ecd82f005 263 Gene3D G3DSA:3.40.50.150 4 188 1.1E-19 T 31-10-2018 TK1917 fcde95b45fd8776a8ce1002ecd82f005 263 SUPERFAMILY SSF53335 24 209 3.53E-25 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TK1917 fcde95b45fd8776a8ce1002ecd82f005 263 Pfam PF13649 Methyltransferase domain 45 144 1.1E-10 T 31-10-2018 TK1872 0f6c0dd2114b54c69ad5743467e2b46f 225 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 17 217 6.6E-71 T 31-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 TK1872 0f6c0dd2114b54c69ad5743467e2b46f 225 Gene3D G3DSA:3.90.850.10 2 221 1.2E-91 T 31-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 TK1872 0f6c0dd2114b54c69ad5743467e2b46f 225 SUPERFAMILY SSF56529 12 221 1.06E-81 T 31-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 TK0512 e17d2f0d2d2dbcc8f9dbaf209f6eb32e 235 Gene3D G3DSA:3.40.390.10 80 230 3.1E-20 T 31-10-2018 IPR024079 Metallopeptidase, catalytic domain superfamily GO:0008237 TK0512 e17d2f0d2d2dbcc8f9dbaf209f6eb32e 235 Pfam PF07998 Peptidase family M54 16 139 8.9E-18 T 31-10-2018 IPR012962 Peptidase M54, archaemetzincin GO:0008270 TK0512 e17d2f0d2d2dbcc8f9dbaf209f6eb32e 235 Pfam PF07998 Peptidase family M54 167 225 8.9E-21 T 31-10-2018 IPR012962 Peptidase M54, archaemetzincin GO:0008270 TK0512 e17d2f0d2d2dbcc8f9dbaf209f6eb32e 235 SUPERFAMILY SSF55486 173 219 1.34E-9 T 31-10-2018 TK0408 1cec4de2f5b326cd8479ad55ccebc7f6 194 Gene3D G3DSA:3.40.630.30 2 162 1.0E-19 T 31-10-2018 TK0408 1cec4de2f5b326cd8479ad55ccebc7f6 194 SUPERFAMILY SSF55729 30 148 9.73E-7 T 31-10-2018 IPR016181 Acyl-CoA N-acyltransferase TK0041 c32c6908b94c744be9692fdb7db444ce 219 TIGRFAM TIGR02537 arch_flag_Nterm: archaeal flagellin N-terminal-like domain 3 26 1.0E-5 T 31-10-2018 IPR013373 Flagellin/pilin, N-terminal TK0041 c32c6908b94c744be9692fdb7db444ce 219 Pfam PF01917 Archaebacterial flagellin 5 205 2.1E-49 T 31-10-2018 IPR002774 Flagellin, archaea GO:0005198|GO:0006928 TK1981 3f35463338f45629cd89ce3da1f7b945 311 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 92 218 4.8E-19 T 31-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 TK1981 3f35463338f45629cd89ce3da1f7b945 311 Gene3D G3DSA:3.40.50.970 96 310 2.4E-68 T 31-10-2018 TK1981 3f35463338f45629cd89ce3da1f7b945 311 SUPERFAMILY SSF52518 16 308 4.71E-69 T 31-10-2018 IPR029061 Thiamin diphosphate-binding fold TK1753 47bb011f657813d6d3eb3c66c58a4b78 252 Pfam PF05763 Protein of unknown function (DUF835) 126 242 1.2E-39 T 31-10-2018 IPR008553 Domain of unknown function DUF835 TK0375 6c4b2197d16de15c96c69a73ebe97fe4 237 Pfam PF01177 Asp/Glu/Hydantoin racemase 9 215 7.2E-14 T 31-10-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 TK0375 6c4b2197d16de15c96c69a73ebe97fe4 237 Gene3D G3DSA:3.40.50.12500 6 237 3.4E-89 T 31-10-2018 TK0375 6c4b2197d16de15c96c69a73ebe97fe4 237 PIRSF PIRSF015736 1 237 2.8E-93 T 31-10-2018 IPR026286 Maleate isomerase/Arylmalonate decarboxylase TK1182 784e909dca2d74335b5ebe13f02c45c2 492 TIGRFAM TIGR00933 2a38: potassium uptake protein, TrkH family 96 469 1.6E-109 T 31-10-2018 IPR004772 TrkH potassium transport family GO:0015379|GO:0016021|GO:0071805 TK1182 784e909dca2d74335b5ebe13f02c45c2 492 Pfam PF02386 Cation transport protein 56 479 1.9E-67 T 31-10-2018 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 TK2191 89ee85dc973e6cc0fbc7ee5b4885ec9a 193 PIRSF PIRSF018933 1 193 1.8E-109 T 31-10-2018 IPR016739 Uncharacterised conserved protein UCP018933 TK0151 943f14a878857469a48bac1370fb560e 143 Pfam PF04024 PspC domain 3 61 9.9E-21 T 31-10-2018 IPR007168 Phage shock protein, PspC, N-terminal TK0276 c269ea1fd637bd19ffda3d4b20d482b8 251 Gene3D G3DSA:3.40.1160.10 2 251 1.2E-40 T 31-10-2018 IPR036393 Acetylglutamate kinase-like superfamily TK0276 c269ea1fd637bd19ffda3d4b20d482b8 251 PIRSF PIRSF000728 1 250 8.0E-48 T 31-10-2018 IPR004662 Acetylglutamate kinase family GO:0005737 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 TK0276 c269ea1fd637bd19ffda3d4b20d482b8 251 SUPERFAMILY SSF53633 3 243 7.99E-33 T 31-10-2018 IPR036393 Acetylglutamate kinase-like superfamily TK0276 c269ea1fd637bd19ffda3d4b20d482b8 251 Hamap MF_02082 [LysW]-aminoadipate/[LysW]-glutamate kinase [lysZ]. 1 251 43.928 T 31-10-2018 IPR037529 [LysW]-aminoadipate/[LysW]-glutamate kinase GO:0016301 TK0276 c269ea1fd637bd19ffda3d4b20d482b8 251 TIGRFAM TIGR00761 argB: acetylglutamate kinase 1 241 1.7E-53 T 31-10-2018 IPR004662 Acetylglutamate kinase family GO:0005737 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 TK0276 c269ea1fd637bd19ffda3d4b20d482b8 251 Pfam PF00696 Amino acid kinase family 2 241 1.3E-24 T 31-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 TK0617 504789a88186a50b4dc98958fbb1833c 208 Gene3D G3DSA:3.40.50.10480 1 187 1.2E-33 T 31-10-2018 TK0617 504789a88186a50b4dc98958fbb1833c 208 SMART SM00879 3 190 4.1E-17 T 31-10-2018 IPR007109 Brix domain TK0617 504789a88186a50b4dc98958fbb1833c 208 Hamap MF_00699 Probable Brix domain-containing ribosomal biogenesis protein. 2 191 29.888 T 31-10-2018 IPR023548 Probable Brix domain-containing ribosomal biogenesis protein TK0617 504789a88186a50b4dc98958fbb1833c 208 SUPERFAMILY SSF52954 1 193 1.37E-35 T 31-10-2018 TK1298 a2d5ba5384e996a22f46ebd0887b1656 355 Pfam PF07318 Protein of unknown function (DUF1464) 5 351 2.2E-137 T 31-10-2018 IPR009927 Protein of unknown function DUF1464 TK1298 a2d5ba5384e996a22f46ebd0887b1656 355 SUPERFAMILY SSF53067 1 304 3.63E-8 T 31-10-2018 TK1298 a2d5ba5384e996a22f46ebd0887b1656 355 PIRSF PIRSF009433 1 354 1.1E-144 T 31-10-2018 IPR009927 Protein of unknown function DUF1464 TK1138 64962d888d278e84ec34d8cdca32af35 154 Pfam PF06146 Phosphate-starvation-inducible E 63 129 5.4E-16 T 31-10-2018 IPR020948 Phosphate-starvation-induced PsiE-like TK0040 bf4c23319e1bfddc04059383992d6168 258 Pfam PF01917 Archaebacterial flagellin 8 244 4.9E-47 T 31-10-2018 IPR002774 Flagellin, archaea GO:0005198|GO:0006928 TK0040 bf4c23319e1bfddc04059383992d6168 258 TIGRFAM TIGR02537 arch_flag_Nterm: archaeal flagellin N-terminal-like domain 6 29 1.2E-5 T 31-10-2018 IPR013373 Flagellin/pilin, N-terminal TK1861 4dba9449739295902973fb1fb72426de 344 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 130 343 7.6E-22 T 31-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TK1861 4dba9449739295902973fb1fb72426de 344 Gene3D G3DSA:1.10.3720.10 108 339 7.3E-16 T 31-10-2018 IPR035906 MetI-like superfamily TK1861 4dba9449739295902973fb1fb72426de 344 SUPERFAMILY SSF161098 97 332 3.14E-12 T 31-10-2018 IPR035906 MetI-like superfamily TK1990 ba30cb9270358c23f280439957a5073a 399 Gene3D G3DSA:3.90.1150.10 7 388 2.0E-146 T 31-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TK1990 ba30cb9270358c23f280439957a5073a 399 PIRSF PIRSF005572 15 399 2.2E-49 T 31-10-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 TK1990 ba30cb9270358c23f280439957a5073a 399 Pfam PF00266 Aminotransferase class-V 18 386 3.1E-138 T 31-10-2018 IPR000192 Aminotransferase class V domain TK1990 ba30cb9270358c23f280439957a5073a 399 SUPERFAMILY SSF53383 5 395 1.04E-117 T 31-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TK1990 ba30cb9270358c23f280439957a5073a 399 Gene3D G3DSA:3.40.640.10 29 287 2.0E-146 T 31-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TK0769 b6cd4211db4ff8fea145a25e861925e3 168 Gene3D G3DSA:2.40.380.10 46 168 3.2E-11 T 31-10-2018 IPR035930 FomD-like superfamily TK0769 b6cd4211db4ff8fea145a25e861925e3 168 Pfam PF04167 Protein of unknown function (DUF402) 57 123 3.1E-13 T 31-10-2018 IPR007295 Domain of unknown function DUF402 TK0769 b6cd4211db4ff8fea145a25e861925e3 168 SUPERFAMILY SSF159234 5 166 2.09E-37 T 31-10-2018 IPR035930 FomD-like superfamily TK1685 6ba41dbbf90295be34f3968bf8949613 284 SUPERFAMILY SSF63380 4 93 7.33E-14 T 31-10-2018 IPR017938 Riboflavin synthase-like beta-barrel TK1685 6ba41dbbf90295be34f3968bf8949613 284 PIRSF PIRSF006816 1 258 6.4E-44 T 31-10-2018 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 TK1685 6ba41dbbf90295be34f3968bf8949613 284 Gene3D G3DSA:2.40.30.10 2 93 5.2E-13 T 31-10-2018 TK1685 6ba41dbbf90295be34f3968bf8949613 284 SUPERFAMILY SSF52343 117 251 1.92E-14 T 31-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain TK1685 6ba41dbbf90295be34f3968bf8949613 284 Gene3D G3DSA:3.40.50.80 101 206 1.5E-15 T 31-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain TK1685 6ba41dbbf90295be34f3968bf8949613 284 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 216 252 3.6E-12 T 31-10-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain TK1018 89821cb7220d6e724ff7da4bcac7b59a 221 Gene3D G3DSA:1.10.10.580 148 217 2.0E-37 T 31-10-2018 IPR023093 ScpA-like, C-terminal TK1018 89821cb7220d6e724ff7da4bcac7b59a 221 Pfam PF02616 Segregation and condensation protein ScpA 18 162 2.5E-11 T 31-10-2018 IPR003768 Segregation and condensation protein A TK1011 78477bb005be2ebd8bd08052b8e17b51 278 Gene3D G3DSA:1.20.1250.20 51 260 3.4E-17 T 31-10-2018 TK1011 78477bb005be2ebd8bd08052b8e17b51 278 SUPERFAMILY SSF103473 23 269 2.75E-26 T 31-10-2018 IPR036259 MFS transporter superfamily TK1011 78477bb005be2ebd8bd08052b8e17b51 278 Pfam PF07690 Major Facilitator Superfamily 19 201 1.6E-14 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TK0167 7b97c064a3ecb2c612c090d1494502b8 535 Pfam PF04055 Radical SAM superfamily 219 403 3.9E-19 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TK0167 7b97c064a3ecb2c612c090d1494502b8 535 SUPERFAMILY SSF102114 216 447 8.76E-14 T 31-10-2018 TK0167 7b97c064a3ecb2c612c090d1494502b8 535 SMART SM00729 215 448 8.1E-5 T 31-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TK0167 7b97c064a3ecb2c612c090d1494502b8 535 Gene3D G3DSA:3.80.30.20 215 410 1.2E-13 T 31-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe TK0498 65db3e72a2274e96e74228200a724956 421 Pfam PF13173 AAA domain 33 164 7.5E-32 T 31-10-2018 TK0498 65db3e72a2274e96e74228200a724956 421 Pfam PF13635 Domain of unknown function (DUF4143) 245 355 1.9E-10 T 31-10-2018 IPR025420 Domain of unknown function DUF4143 TK0498 65db3e72a2274e96e74228200a724956 421 SUPERFAMILY SSF52540 20 164 4.0E-19 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK0189 bca2bdd61aaa74fe0ded3d08e62c2bc0 136 Pfam PF02566 OsmC-like protein 31 118 5.6E-16 T 31-10-2018 IPR003718 OsmC/Ohr family TK0189 bca2bdd61aaa74fe0ded3d08e62c2bc0 136 Gene3D G3DSA:3.30.300.20 4 133 1.0E-33 T 31-10-2018 IPR015946 K homology domain-like, alpha/beta TK0189 bca2bdd61aaa74fe0ded3d08e62c2bc0 136 SUPERFAMILY SSF82784 11 132 6.02E-31 T 31-10-2018 IPR036102 OsmC/Ohr superfamily TK2262 9098e05845ec6cb2edb21d8bd4b3a8bc 136 SUPERFAMILY SSF88723 3 131 4.77E-18 T 31-10-2018 IPR029060 PIN-like domain superfamily TK2262 9098e05845ec6cb2edb21d8bd4b3a8bc 136 Pfam PF01850 PIN domain 4 124 2.6E-12 T 31-10-2018 IPR002716 PIN domain TK2262 9098e05845ec6cb2edb21d8bd4b3a8bc 136 Gene3D G3DSA:3.40.50.1010 2 134 6.3E-11 T 31-10-2018 TK1737 15c105e9d5122b04d094f35fc0110efe 154 Pfam PF00156 Phosphoribosyl transferase domain 14 150 1.9E-27 T 31-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 TK1737 15c105e9d5122b04d094f35fc0110efe 154 SUPERFAMILY SSF53271 3 146 1.84E-33 T 31-10-2018 IPR029057 Phosphoribosyltransferase-like TK1737 15c105e9d5122b04d094f35fc0110efe 154 Gene3D G3DSA:3.40.50.2020 1 154 9.0E-52 T 31-10-2018 TK1471 07d797af19837167f35048471e91ddc1 225 TIGRFAM TIGR00035 asp_race: aspartate racemase 1 225 1.1E-50 T 31-10-2018 IPR004380 Aspartate racemase GO:0006520|GO:0016855 TK1471 07d797af19837167f35048471e91ddc1 225 SUPERFAMILY SSF53681 1 114 3.71E-26 T 31-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 TK1471 07d797af19837167f35048471e91ddc1 225 Gene3D G3DSA:3.40.50.1860 4 214 4.1E-71 T 31-10-2018 TK1471 07d797af19837167f35048471e91ddc1 225 SUPERFAMILY SSF53681 116 223 7.03E-27 T 31-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 TK1471 07d797af19837167f35048471e91ddc1 225 Gene3D G3DSA:3.40.50.1860 102 210 4.1E-71 T 31-10-2018 TK1471 07d797af19837167f35048471e91ddc1 225 Pfam PF01177 Asp/Glu/Hydantoin racemase 7 219 2.0E-51 T 31-10-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 TK0722 33e6883db8b4ea2d41bfdf5d7fd7cb9d 143 Pfam PF04140 Isoprenylcysteine carboxyl methyltransferase (ICMT) family 56 122 9.7E-5 T 31-10-2018 IPR007269 Isoprenylcysteine carboxyl methyltransferase GO:0004671|GO:0006481|GO:0016021 Reactome: R-HSA-163841 TK0722 33e6883db8b4ea2d41bfdf5d7fd7cb9d 143 Gene3D G3DSA:1.20.120.1630 3 142 5.8E-24 T 31-10-2018 TK0298 62cab59f3a6a473f1884cdd45a2502de 431 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 264 341 1.0E-10 T 31-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal TK0298 62cab59f3a6a473f1884cdd45a2502de 431 Pfam PF07282 Putative transposase DNA-binding domain 314 383 1.6E-21 T 31-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal TK0298 62cab59f3a6a473f1884cdd45a2502de 431 Pfam PF01385 Probable transposase 171 294 9.2E-36 T 31-10-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 TK0729 810a7d3a6fb036d29e0aac9d1c30ff36 200 Pfam PF08241 Methyltransferase domain 40 134 2.0E-26 T 31-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 TK0729 810a7d3a6fb036d29e0aac9d1c30ff36 200 ProSitePatterns PS01184 ubiE/COQ5 methyltransferase family signature 2. 124 138 - T 31-10-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 TK0729 810a7d3a6fb036d29e0aac9d1c30ff36 200 Gene3D G3DSA:3.40.50.150 4 188 3.4E-34 T 31-10-2018 TK0729 810a7d3a6fb036d29e0aac9d1c30ff36 200 SUPERFAMILY SSF53335 3 185 1.18E-36 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TK1802 39ffb204a68bc1972b10b3818ffe26c2 473 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 284 472 1.6E-28 T 31-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TK1802 39ffb204a68bc1972b10b3818ffe26c2 473 Gene3D G3DSA:1.10.3720.10 257 472 4.8E-23 T 31-10-2018 IPR035906 MetI-like superfamily TK1802 39ffb204a68bc1972b10b3818ffe26c2 473 SUPERFAMILY SSF161098 261 454 1.31E-23 T 31-10-2018 IPR035906 MetI-like superfamily TK1802 39ffb204a68bc1972b10b3818ffe26c2 473 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 11 65 1.5E-5 T 31-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain TK1494 0bf2887774929b68db56c35cc477c2f6 109 Pfam PF03551 Transcriptional regulator PadR-like family 21 94 6.1E-19 T 31-10-2018 IPR005149 Transcription regulator PadR, N-terminal TK1494 0bf2887774929b68db56c35cc477c2f6 109 SUPERFAMILY SSF46785 4 106 1.7E-23 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TK1494 0bf2887774929b68db56c35cc477c2f6 109 Gene3D G3DSA:1.10.10.10 3 108 2.1E-26 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TK0386 8c3a7b2ea69b08a285d1acb2278d8957 712 Gene3D G3DSA:2.60.40.2050 170 292 1.1E-32 T 31-10-2018 TK0386 8c3a7b2ea69b08a285d1acb2278d8957 712 Gene3D G3DSA:2.60.40.2050 293 362 3.1E-21 T 31-10-2018 TK0386 8c3a7b2ea69b08a285d1acb2278d8957 712 Gene3D G3DSA:1.20.120.870 530 671 9.2E-45 T 31-10-2018 TK1851 d96a9fd53bb5536e9e015608a3adbb20 305 Gene3D G3DSA:1.20.81.30 94 210 1.6E-8 T 31-10-2018 TK1851 d96a9fd53bb5536e9e015608a3adbb20 305 Pfam PF00482 Type II secretion system (T2SS), protein F 105 229 2.4E-18 T 31-10-2018 IPR018076 Type II secretion system F domain TK2306 88556446f506f66073286ff030753778 156 Pfam PF11848 Domain of unknown function (DUF3368) 111 153 5.8E-9 T 31-10-2018 IPR021799 Protein of unknown function DUF3368 TK1729 d1d12e7c48682b311939a9bb4e1ceb28 219 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 71 179 3.5E-7 T 31-10-2018 IPR038731 Glycosyltransferase RgtA/B/C/D-like TK1065 eb9ce90bc24f295c91527dd8acfa4185 82 Pfam PF02597 ThiS family 3 82 1.0E-21 T 31-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 TK1065 eb9ce90bc24f295c91527dd8acfa4185 82 Gene3D G3DSA:3.10.20.30 1 82 1.6E-24 T 31-10-2018 IPR012675 Beta-grasp domain superfamily TK1065 eb9ce90bc24f295c91527dd8acfa4185 82 SUPERFAMILY SSF54285 2 82 3.2E-21 T 31-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp TK1065 eb9ce90bc24f295c91527dd8acfa4185 82 TIGRFAM TIGR01687 moaD_arch: MoaD family protein 1 82 1.5E-22 T 31-10-2018 IPR010038 MoaD, archaeal-type TK0315 6db57dc19ea81da9ddebfd91631d0e90 81 Hamap MF_01245 UPF0248 protein . 10 79 19.206 T 31-10-2018 IPR007547 Uncharacterised protein family UPF0248 TK0315 6db57dc19ea81da9ddebfd91631d0e90 81 Pfam PF04457 Protein of unknown function (DUF504) 26 77 1.9E-15 T 31-10-2018 IPR007547 Uncharacterised protein family UPF0248 TK2232 124f124aff3591f8419842139afaa540 211 SMART SM00849 7 175 1.6E-18 T 31-10-2018 IPR001279 Metallo-beta-lactamase TK2232 124f124aff3591f8419842139afaa540 211 Pfam PF13483 Beta-lactamase superfamily domain 2 175 2.0E-28 T 31-10-2018 TK2232 124f124aff3591f8419842139afaa540 211 SUPERFAMILY SSF56281 1 198 2.95E-37 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TK2232 124f124aff3591f8419842139afaa540 211 Gene3D G3DSA:3.60.15.10 1 201 4.0E-49 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TK1029 3fb1bc2a6e189daebacf1b1f817173a1 142 SMART SM00465 18 113 1.2E-7 T 31-10-2018 IPR000305 GIY-YIG endonuclease TK1029 3fb1bc2a6e189daebacf1b1f817173a1 142 Pfam PF01986 Domain of unknown function DUF123 25 110 1.4E-21 T 31-10-2018 IPR002837 Protein of unknown function DUF123 TK1909 ba6f2d5e6ea10226770f100f9da7237b 352 Pfam PF04138 GtrA-like protein 236 351 6.0E-27 T 31-10-2018 IPR007267 GtrA-like protein GO:0000271|GO:0016021 TK1909 ba6f2d5e6ea10226770f100f9da7237b 352 Pfam PF00535 Glycosyl transferase family 2 4 168 8.4E-39 T 31-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TK1909 ba6f2d5e6ea10226770f100f9da7237b 352 Gene3D G3DSA:3.90.550.10 1 240 4.9E-54 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TK1909 ba6f2d5e6ea10226770f100f9da7237b 352 SUPERFAMILY SSF53448 2 227 8.16E-46 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TK2291 ad3b081500323e3f57ac2fc7550d36bb 198 Gene3D G3DSA:1.10.10.10 4 105 4.9E-28 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TK2291 ad3b081500323e3f57ac2fc7550d36bb 198 Pfam PF01022 Bacterial regulatory protein, arsR family 16 61 5.6E-14 T 31-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TK2291 ad3b081500323e3f57ac2fc7550d36bb 198 SMART SM00418 9 89 1.1E-17 T 31-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TK2291 ad3b081500323e3f57ac2fc7550d36bb 198 SUPERFAMILY SSF46785 6 172 5.15E-29 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TK0205 c005fb53168208ead5c9d6f0de1b169f 221 Gene3D G3DSA:3.40.50.300 4 215 1.3E-44 T 31-10-2018 TK0894 6fcae939c790d711bb53d057e59ff9a1 277 ProDom PD039347 PF1398 MJ0538 PH1392 4 256 1.0E-142 T 31-10-2018 IPR020292 Uncharacterised protein family MJ0538 TK0892 35e73bd6c33a170689b22fb8f577fd78 242 Pfam PF01522 Polysaccharide deacetylase 4 126 1.8E-15 T 31-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 TK0892 35e73bd6c33a170689b22fb8f577fd78 242 SUPERFAMILY SSF88713 3 234 8.62E-28 T 31-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 TK0892 35e73bd6c33a170689b22fb8f577fd78 242 Gene3D G3DSA:3.20.20.370 2 236 4.6E-36 T 31-10-2018 TK1424 f7da99b0c409b78a60731949a60f2b4c 402 SUPERFAMILY SSF53743 1 281 6.8E-45 T 31-10-2018 IPR009015 L-fucose isomerase, N-terminal/central domain superfamily GO:0005737|GO:0005996|GO:0016861 TK1754 6713cf3ba029c70e2e90a1f0cb088373 786 Gene3D G3DSA:3.40.50.880 440 654 4.1E-14 T 31-10-2018 IPR029062 Class I glutamine amidotransferase-like TK1754 6713cf3ba029c70e2e90a1f0cb088373 786 Pfam PF02449 Beta-galactosidase 25 415 5.0E-72 T 31-10-2018 IPR013529 Glycoside hydrolase, family 42, N-terminal GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 TK1754 6713cf3ba029c70e2e90a1f0cb088373 786 SUPERFAMILY SSF52317 477 628 1.81E-6 T 31-10-2018 IPR029062 Class I glutamine amidotransferase-like TK1754 6713cf3ba029c70e2e90a1f0cb088373 786 PRINTS PR00742 Glycosyl hydrolase family 35 signature 14 31 8.2E-7 T 31-10-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 TK1754 6713cf3ba029c70e2e90a1f0cb088373 786 PRINTS PR00742 Glycosyl hydrolase family 35 signature 94 113 8.2E-7 T 31-10-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 TK1754 6713cf3ba029c70e2e90a1f0cb088373 786 SUPERFAMILY SSF51445 4 421 6.49E-63 T 31-10-2018 IPR017853 Glycoside hydrolase superfamily TK1524 5e7e005953af13e6935778989ceec221 126 SMART SM01393 18 125 2.7E-63 T 31-10-2018 IPR001515 Ribosomal protein L32e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1524 5e7e005953af13e6935778989ceec221 126 SUPERFAMILY SSF52042 5 126 6.28E-47 T 31-10-2018 IPR036351 Ribosomal protein L32e superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1524 5e7e005953af13e6935778989ceec221 126 ProDom PD003823 RIBOSOMAL L32 RIBONUCLEOPROTEIN 60S L32E 50S L32 STRAIN CHROMOSOME DIRECT 21 126 3.0E-56 T 31-10-2018 IPR001515 Ribosomal protein L32e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1524 5e7e005953af13e6935778989ceec221 126 Hamap MF_00810 50S ribosomal protein L32e [rpl32e]. 2 126 32.098 T 31-10-2018 IPR023654 Ribosomal protein L32e, archaeal GO:0003735|GO:0005840|GO:0006412 TK1524 5e7e005953af13e6935778989ceec221 126 Pfam PF01655 Ribosomal protein L32 18 125 4.5E-41 T 31-10-2018 IPR001515 Ribosomal protein L32e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1524 5e7e005953af13e6935778989ceec221 126 ProSitePatterns PS00580 Ribosomal protein L32e signature. 21 43 - T 31-10-2018 IPR018263 Ribosomal protein L32e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK0268 2c517f9c560d45684b844ea555a47967 304 Gene3D G3DSA:3.20.20.70 4 264 8.3E-108 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TK0268 2c517f9c560d45684b844ea555a47967 304 SUPERFAMILY SSF51569 11 257 2.56E-97 T 31-10-2018 TK0268 2c517f9c560d45684b844ea555a47967 304 TIGRFAM TIGR01361 DAHP_synth_Bsub: 3-deoxy-7-phosphoheptulonate synthase 10 257 4.3E-128 T 31-10-2018 IPR006268 Phospho-2-dehydro-3-deoxyheptonate aldolase, subtype 2 GO:0009073|GO:0016832 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 TK0268 2c517f9c560d45684b844ea555a47967 304 Pfam PF00793 DAHP synthetase I family 19 254 1.6E-79 T 31-10-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 TK2012 c075ec67dee1fe0f53e1e0a7febb7352 138 Gene3D G3DSA:3.30.70.20 16 112 1.7E-9 T 31-10-2018 TK2012 c075ec67dee1fe0f53e1e0a7febb7352 138 SUPERFAMILY SSF54862 24 100 1.76E-12 T 31-10-2018 TK2012 c075ec67dee1fe0f53e1e0a7febb7352 138 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 45 56 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TK1550 a391b7ca00c894e067afcd66105c4a37 299 Pfam PF00152 tRNA synthetases class II (D, K and N) 4 292 2.3E-43 T 31-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 TK1550 a391b7ca00c894e067afcd66105c4a37 299 SUPERFAMILY SSF55681 9 295 4.04E-55 T 31-10-2018 TK1550 a391b7ca00c894e067afcd66105c4a37 299 Gene3D G3DSA:3.30.930.10 1 298 6.0E-77 T 31-10-2018 TK0221 73cc13bd3fefbe83292280470bfa87cc 137 Gene3D G3DSA:1.20.120.330 2 129 1.2E-24 T 31-10-2018 TK0221 73cc13bd3fefbe83292280470bfa87cc 137 SMART SM00748 10 121 1.4E-32 T 31-10-2018 IPR007842 HEPN domain TK0221 73cc13bd3fefbe83292280470bfa87cc 137 SUPERFAMILY SSF81593 8 130 2.2E-28 T 31-10-2018 TK0221 73cc13bd3fefbe83292280470bfa87cc 137 Pfam PF05168 HEPN domain 6 127 7.1E-28 T 31-10-2018 IPR007842 HEPN domain TK0480 c2de212fe3e71d7e9c42bda52e2dccf7 206 SMART SM00471 30 147 1.1E-11 T 31-10-2018 IPR003607 HD/PDEase domain TK0480 c2de212fe3e71d7e9c42bda52e2dccf7 206 Gene3D G3DSA:1.10.3210.50 12 206 8.4E-67 T 31-10-2018 TK0480 c2de212fe3e71d7e9c42bda52e2dccf7 206 Pfam PF01966 HD domain 35 137 7.4E-20 T 31-10-2018 IPR006674 HD domain TK0480 c2de212fe3e71d7e9c42bda52e2dccf7 206 TIGRFAM TIGR00277 HDIG: HDIG domain 34 95 1.8E-9 T 31-10-2018 IPR006675 HDIG domain TK0480 c2de212fe3e71d7e9c42bda52e2dccf7 206 SUPERFAMILY SSF109604 14 205 1.96E-63 T 31-10-2018 TK1964 7b857e7854652705923d69d8e19beaea 172 TIGRFAM TIGR00723 ttdB_fumA_fumB: hydrolyase, tartrate beta subunit/fumarate domain protein, Fe-S type 11 172 7.4E-61 T 31-10-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 TK1964 7b857e7854652705923d69d8e19beaea 172 Pfam PF05683 Fumarase C-terminus 3 171 7.1E-41 T 31-10-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 TK1964 7b857e7854652705923d69d8e19beaea 172 Gene3D G3DSA:3.20.130.10 1 172 8.1E-67 T 31-10-2018 IPR036660 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain superfamily GO:0016836 TK1964 7b857e7854652705923d69d8e19beaea 172 SUPERFAMILY SSF117457 8 171 8.76E-52 T 31-10-2018 IPR036660 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain superfamily GO:0016836 TK1185 061bbfb455b0710b75993472bde183e1 164 SUPERFAMILY SSF88723 14 136 1.77E-8 T 31-10-2018 IPR029060 PIN-like domain superfamily TK1185 061bbfb455b0710b75993472bde183e1 164 Pfam PF13470 PIN domain 14 131 1.7E-19 T 31-10-2018 IPR002716 PIN domain TK1185 061bbfb455b0710b75993472bde183e1 164 SMART SM00670 13 134 1.9E-12 T 31-10-2018 IPR002716 PIN domain TK1185 061bbfb455b0710b75993472bde183e1 164 TIGRFAM TIGR00305 TIGR00305: putative toxin-antitoxin system toxin component, PIN family 14 131 1.4E-20 T 31-10-2018 IPR002850 PIN family, putative toxin-antitoxin system toxin component TK2188 af98c7ae46b0116e7f82239edd2ff0e7 437 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 102 247 8.8E-13 T 31-10-2018 IPR038731 Glycosyltransferase RgtA/B/C/D-like TK1207 20f6037df785810905ab10dbb95dd669 154 Gene3D G3DSA:1.25.40.10 49 153 7.8E-17 T 31-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TK1207 20f6037df785810905ab10dbb95dd669 154 SUPERFAMILY SSF48452 23 145 3.35E-7 T 31-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TK1724 238fd22d564175000f2fe93b36e23e8c 336 SUPERFAMILY SSF53795 133 215 2.69E-6 T 31-10-2018 TK0176 171179f0a531d144817f57dbd9c5879d 110 Gene3D G3DSA:3.40.50.1010 2 110 2.7E-11 T 31-10-2018 TK0176 171179f0a531d144817f57dbd9c5879d 110 SUPERFAMILY SSF88723 2 106 2.24E-15 T 31-10-2018 IPR029060 PIN-like domain superfamily TK0904 d1519d661346ae8bd0e534433059fdd2 97 SUPERFAMILY SSF46785 2 96 5.98E-35 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TK0904 d1519d661346ae8bd0e534433059fdd2 97 Gene3D G3DSA:2.20.28.10 1 97 4.9E-34 T 31-10-2018 TK1267 3319c7f10c6427f1b3b6502cc18bd448 288 SUPERFAMILY SSF103481 192 287 1.7E-13 T 31-10-2018 TK1267 3319c7f10c6427f1b3b6502cc18bd448 288 SUPERFAMILY SSF103481 42 144 2.62E-14 T 31-10-2018 TK1267 3319c7f10c6427f1b3b6502cc18bd448 288 Pfam PF00892 EamA-like transporter family 6 140 1.2E-23 T 31-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TK1267 3319c7f10c6427f1b3b6502cc18bd448 288 Pfam PF00892 EamA-like transporter family 152 287 8.3E-23 T 31-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TK0959 053fe265879bbed9c25cbbc1d76c4f1b 121 Pfam PF09685 Domain of unknown function (DUF4870) 24 108 7.8E-9 T 31-10-2018 IPR019109 Protein of unknown function DUF4870 TK1778 e0c9a001902300600389f50933de3379 271 Gene3D G3DSA:3.60.15.10 1 253 5.2E-30 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TK1778 e0c9a001902300600389f50933de3379 271 SUPERFAMILY SSF56281 3 254 4.87E-38 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TK1778 e0c9a001902300600389f50933de3379 271 Pfam PF12706 Beta-lactamase superfamily domain 32 220 1.3E-27 T 31-10-2018 IPR001279 Metallo-beta-lactamase TK0367 d845c7265beeec06edf38fe4ddffcd05 158 Pfam PF06197 Protein of unknown function (DUF998) 4 149 1.2E-12 T 31-10-2018 IPR009339 Protein of unknown function DUF998 TK0731 42b60b0908f5191cc7544ddf0f9c02e0 246 SUPERFAMILY SSF52540 2 226 1.81E-48 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK0731 42b60b0908f5191cc7544ddf0f9c02e0 246 Pfam PF00005 ABC transporter 17 167 7.8E-23 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TK0731 42b60b0908f5191cc7544ddf0f9c02e0 246 Gene3D G3DSA:3.40.50.300 1 243 2.4E-58 T 31-10-2018 TK0731 42b60b0908f5191cc7544ddf0f9c02e0 246 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TK0731 42b60b0908f5191cc7544ddf0f9c02e0 246 SMART SM00382 26 219 9.0E-10 T 31-10-2018 IPR003593 AAA+ ATPase domain TK0731 42b60b0908f5191cc7544ddf0f9c02e0 246 TIGRFAM TIGR01978 sufC: FeS assembly ATPase SufC 2 240 1.6E-85 T 31-10-2018 IPR010230 FeS cluster assembly SUF system, ATPase SufC GO:0005524 TK0439 9f5a5b3f99f7e143955f193bdbdfb7e0 195 PIRSF PIRSF019711 1 195 4.2E-101 T 31-10-2018 IPR016765 Metal-dependent membrane protease, PF1846 type, predicted TK0439 9f5a5b3f99f7e143955f193bdbdfb7e0 195 Pfam PF02517 CAAX protease self-immunity 107 184 1.8E-8 T 31-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 TK1168 30c208a514c482fe2abd3f8f1958b5ec 209 Pfam PF09840 Uncharacterized protein conserved in archaea (DUF2067) 9 196 9.0E-55 T 31-10-2018 IPR019202 Protein of unknown function DUF2067 TK0704 742da1f905de7f81191b4a341e554a44 209 SUPERFAMILY SSF53335 7 182 3.31E-35 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TK0704 742da1f905de7f81191b4a341e554a44 209 Gene3D G3DSA:3.40.50.150 2 209 8.5E-64 T 31-10-2018 TK0704 742da1f905de7f81191b4a341e554a44 209 Pfam PF08241 Methyltransferase domain 44 128 2.8E-19 T 31-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 TK2083 c71b8c06db69ceecb2ff846eb660a267 88 Pfam PF13244 Domain of unknown function (DUF4040) 17 82 5.2E-17 T 31-10-2018 IPR025383 Domain of unknown function DUF4040 TK0909 a78d9e60863b61b882be397db872e562 68 Pfam PF01954 Protein of unknown function DUF104 1 54 3.1E-19 T 31-10-2018 IPR008203 Uncharacterised protein family UPF0165 TK0909 a78d9e60863b61b882be397db872e562 68 Gene3D G3DSA:4.10.1150.10 1 63 2.5E-10 T 31-10-2018 IPR024069 AF2212-like domain superfamily TK0909 a78d9e60863b61b882be397db872e562 68 SUPERFAMILY SSF141694 1 58 1.6E-14 T 31-10-2018 TK1181 5066b5098f28b638267917204b249e66 279 Gene3D G3DSA:3.40.50.300 2 259 3.3E-68 T 31-10-2018 TK1181 5066b5098f28b638267917204b249e66 279 Pfam PF00005 ABC transporter 21 178 1.7E-21 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TK1181 5066b5098f28b638267917204b249e66 279 SUPERFAMILY SSF52540 3 238 4.55E-56 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK1181 5066b5098f28b638267917204b249e66 279 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TK1181 5066b5098f28b638267917204b249e66 279 SMART SM00382 30 226 2.4E-10 T 31-10-2018 IPR003593 AAA+ ATPase domain TK1458 c456c6f1b414a9672d2e11c3de9afa20 395 Pfam PF01769 Divalent cation transporter 60 184 3.0E-21 T 31-10-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 TK1458 c456c6f1b414a9672d2e11c3de9afa20 395 Pfam PF01769 Divalent cation transporter 264 388 1.2E-18 T 31-10-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 TK1458 c456c6f1b414a9672d2e11c3de9afa20 395 SUPERFAMILY SSF161093 16 189 1.44E-30 T 31-10-2018 IPR036739 SLC41 divalent cation transporters, integral membrane domain superfamily GO:0006812|GO:0008324 TK1458 c456c6f1b414a9672d2e11c3de9afa20 395 Gene3D G3DSA:1.10.357.20 217 395 2.9E-12 T 31-10-2018 IPR038048 Magnesium transporter MgtE, transmembrane domain TK1458 c456c6f1b414a9672d2e11c3de9afa20 395 Gene3D G3DSA:1.10.357.20 13 190 4.0E-11 T 31-10-2018 IPR038048 Magnesium transporter MgtE, transmembrane domain TK1458 c456c6f1b414a9672d2e11c3de9afa20 395 SUPERFAMILY SSF161093 222 394 1.83E-25 T 31-10-2018 IPR036739 SLC41 divalent cation transporters, integral membrane domain superfamily GO:0006812|GO:0008324 TK0261 f70644848a05f1c126f41537cecbc551 58 SMART SM00830 1 52 0.0026 T 31-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 TK0261 f70644848a05f1c126f41537cecbc551 58 Gene3D G3DSA:1.20.59.10 1 51 2.4E-14 T 31-10-2018 IPR036979 Chorismate mutase domain superfamily GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 TK0261 f70644848a05f1c126f41537cecbc551 58 SUPERFAMILY SSF48600 1 49 9.46E-10 T 31-10-2018 IPR036263 Chorismate mutase type II superfamily GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 TK0261 f70644848a05f1c126f41537cecbc551 58 Pfam PF01817 Chorismate mutase type II 1 49 1.1E-9 T 31-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 TK2007 98dec2a05a19904ddddaf7dd6ef302cb 248 Hamap MF_02040 Iron-sulfur cluster carrier protein. 13 242 28.646 T 31-10-2018 IPR019591 Mrp/NBP35 ATP-binding protein TK2007 98dec2a05a19904ddddaf7dd6ef302cb 248 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 18 235 1.6E-56 T 31-10-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 TK2007 98dec2a05a19904ddddaf7dd6ef302cb 248 Gene3D G3DSA:3.40.50.300 1 230 1.6E-71 T 31-10-2018 TK2007 98dec2a05a19904ddddaf7dd6ef302cb 248 SUPERFAMILY SSF52540 19 227 4.72E-43 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK0755 fa7482f129b12500a877fed79b298ca8 165 Pfam PF01936 NYN domain 31 161 2.9E-18 T 31-10-2018 IPR021139 NYN domain, limkain-b1-type TK0755 fa7482f129b12500a877fed79b298ca8 165 ProDom PD010896 FAMILY DUF88 ARCHAEBACTERIAL PROTEIN MJ0482 PH0073 PF2040 VNG1608C MA3857 PF2039 32 104 9.0E-34 T 31-10-2018 TK0755 fa7482f129b12500a877fed79b298ca8 165 TIGRFAM TIGR00288 TIGR00288: TIGR00288 family protein 22 164 9.7E-64 T 31-10-2018 IPR002790 Conserved hypothetical protein CHP00288 TK0755 fa7482f129b12500a877fed79b298ca8 165 Gene3D G3DSA:3.40.50.1010 22 164 1.3E-8 T 31-10-2018 TK1952 309dc12c2f8733ad18cb9fc1fe8325ce 56 Hamap MF_00751 Preprotein translocase subunit SecG [secG]. 1 51 14.678 T 31-10-2018 IPR023531 Preprotein translocase subunit SecG TK1952 309dc12c2f8733ad18cb9fc1fe8325ce 56 Pfam PF03911 Sec61beta family 11 51 2.0E-16 T 31-10-2018 IPR016482 Protein transport protein SecG/Sec61-beta/Sbh Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TK0958 1b0d12369f73eda8488f652322c3bba8 77 Gene3D G3DSA:2.30.30.90 14 77 7.2E-21 T 31-10-2018 IPR038157 Ferrous iron transporter, core domain TK0958 1b0d12369f73eda8488f652322c3bba8 77 SUPERFAMILY SSF50037 7 76 6.87E-18 T 31-10-2018 IPR008988 Transcriptional repressor, C-terminal TK0958 1b0d12369f73eda8488f652322c3bba8 77 Pfam PF04023 FeoA domain 5 75 6.8E-20 T 31-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 TK0958 1b0d12369f73eda8488f652322c3bba8 77 SMART SM00899 5 76 1.1E-21 T 31-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 TK0017 11b3ee8eccbca93ee8feabbacf23e101 71 SUPERFAMILY SSF89447 1 53 2.22E-7 T 31-10-2018 IPR037914 SpoVT-AbrB domain superfamily TK0017 11b3ee8eccbca93ee8feabbacf23e101 71 SMART SM00966 6 47 7.0E-5 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 TK0017 11b3ee8eccbca93ee8feabbacf23e101 71 Pfam PF02381 MraZ protein, putative antitoxin-like 8 42 3.2E-5 T 31-10-2018 IPR020603 MraZ domain TK0829 0f731dd5560e76846a93dfc890507828 181 Pfam PF06197 Protein of unknown function (DUF998) 14 177 1.5E-23 T 31-10-2018 IPR009339 Protein of unknown function DUF998 TK0049 04d89c9f66bc8b51ce1bd6a8577801c9 579 Pfam PF00482 Type II secretion system (T2SS), protein F 338 462 1.4E-9 T 31-10-2018 IPR018076 Type II secretion system F domain TK0049 04d89c9f66bc8b51ce1bd6a8577801c9 579 Pfam PF00482 Type II secretion system (T2SS), protein F 88 215 1.4E-8 T 31-10-2018 IPR018076 Type II secretion system F domain TK1094 39ef1dc621e05ab493c996e898eba0bd 399 Pfam PF00155 Aminotransferase class I and II 31 387 1.6E-60 T 31-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 TK1094 39ef1dc621e05ab493c996e898eba0bd 399 SUPERFAMILY SSF53383 12 395 4.39E-107 T 31-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TK1094 39ef1dc621e05ab493c996e898eba0bd 399 Gene3D G3DSA:3.90.1150.10 24 390 7.8E-145 T 31-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TK1094 39ef1dc621e05ab493c996e898eba0bd 399 Gene3D G3DSA:3.40.640.10 53 294 7.8E-145 T 31-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TK1094 39ef1dc621e05ab493c996e898eba0bd 399 PIRSF PIRSF000517 3 399 3.1E-78 T 31-10-2018 IPR005958 Tyrosine/nicotianamine aminotransferase GO:0006520|GO:0008483|GO:0030170 Reactome: R-HSA-71182 TK1743 b40d669ecab41db4b26b2e1107e56429 578 SUPERFAMILY SSF88713 2 224 4.0E-15 T 31-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 TK0987 9f911f937197be2bd4f4d207fb74c72c 232 Gene3D G3DSA:3.30.930.10 3 176 8.6E-56 T 31-10-2018 TK0987 9f911f937197be2bd4f4d207fb74c72c 232 Pfam PF02237 Biotin protein ligase C terminal domain 184 229 4.5E-8 T 31-10-2018 IPR003142 Biotin protein ligase, C-terminal GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 TK0987 9f911f937197be2bd4f4d207fb74c72c 232 Gene3D G3DSA:2.30.30.100 184 230 3.0E-8 T 31-10-2018 TK0987 9f911f937197be2bd4f4d207fb74c72c 232 SUPERFAMILY SSF50037 184 229 6.41E-7 T 31-10-2018 IPR008988 Transcriptional repressor, C-terminal TK0987 9f911f937197be2bd4f4d207fb74c72c 232 Pfam PF03099 Biotin/lipoate A/B protein ligase family 11 122 3.5E-18 T 31-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 TK0987 9f911f937197be2bd4f4d207fb74c72c 232 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 5 228 2.7E-54 T 31-10-2018 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 TK0987 9f911f937197be2bd4f4d207fb74c72c 232 SUPERFAMILY SSF55681 2 170 2.8E-51 T 31-10-2018 TK1838 81dd5c38c6cda55d8290f76be90a3ea0 439 Gene3D G3DSA:1.50.10.20 2 170 7.3E-17 T 31-10-2018 TK1838 81dd5c38c6cda55d8290f76be90a3ea0 439 SUPERFAMILY SSF48239 3 378 8.17E-17 T 31-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid TK0371 d29499a3a65a874590f82e8e92f93be7 93 Gene3D G3DSA:3.30.920.30 1 65 8.1E-8 T 31-10-2018 IPR038570 HicA superfamily TK0371 d29499a3a65a874590f82e8e92f93be7 93 Pfam PF07927 HicA toxin of bacterial toxin-antitoxin, 3 63 3.3E-9 T 31-10-2018 IPR012933 HicA mRNA interferase family GO:0003729 TK0371 d29499a3a65a874590f82e8e92f93be7 93 SUPERFAMILY SSF54786 1 69 7.45E-7 T 31-10-2018 TK1087 e6a158961316c1cc5690f020b8cbf974 67 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 14 25 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TK1087 e6a158961316c1cc5690f020b8cbf974 67 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 43 54 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TK1087 e6a158961316c1cc5690f020b8cbf974 67 SUPERFAMILY SSF54862 3 64 1.0E-17 T 31-10-2018 TK1087 e6a158961316c1cc5690f020b8cbf974 67 Gene3D G3DSA:3.30.70.20 1 35 4.7E-7 T 31-10-2018 TK1087 e6a158961316c1cc5690f020b8cbf974 67 Gene3D G3DSA:3.30.70.20 36 65 1.6E-6 T 31-10-2018 TK1087 e6a158961316c1cc5690f020b8cbf974 67 Pfam PF00037 4Fe-4S binding domain 7 30 5.0E-7 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TK1087 e6a158961316c1cc5690f020b8cbf974 67 Pfam PF00037 4Fe-4S binding domain 40 58 2.0E-8 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TK1667 518d9d8de9e8681373395e1f6a38fd4d 221 Pfam PF04021 Class III signal peptide 2 27 3.6E-8 T 31-10-2018 IPR007166 Class III signal peptide motif TK1718 b0d5c9680dc86b5f6d09d8dc31c27a2d 766 Gene3D G3DSA:3.40.50.12610 467 574 6.6E-13 T 31-10-2018 TK2234 eb5d52f6fb0665c72520e0f94040e7ed 239 Pfam PF07758 Protein of unknown function (DUF1614) 61 238 3.5E-54 T 31-10-2018 IPR011672 Protein of unknown function DUF1614 TK0977 428e659255ac0a894d9b5072caea3a62 765 SUPERFAMILY SSF51445 226 691 1.44E-106 T 31-10-2018 IPR017853 Glycoside hydrolase superfamily TK0977 428e659255ac0a894d9b5072caea3a62 765 Pfam PF16561 Glycogen recognition site of AMP-activated protein kinase 86 147 5.2E-11 T 31-10-2018 IPR032640 AMP-activated protein kinase, glycogen-binding domain Reactome: R-HSA-1445148|Reactome: R-HSA-1632852|Reactome: R-HSA-2151209|Reactome: R-HSA-380972|Reactome: R-HSA-5628897|Reactome: R-HSA-6804756 TK0977 428e659255ac0a894d9b5072caea3a62 765 Pfam PF00128 Alpha amylase, catalytic domain 349 654 2.3E-64 T 31-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 TK0977 428e659255ac0a894d9b5072caea3a62 765 Gene3D G3DSA:3.90.400.10 422 475 5.1E-121 T 31-10-2018 TK0977 428e659255ac0a894d9b5072caea3a62 765 SUPERFAMILY SSF81296 90 180 6.06E-16 T 31-10-2018 IPR014756 Immunoglobulin E-set TK0977 428e659255ac0a894d9b5072caea3a62 765 Gene3D G3DSA:2.60.40.10 79 183 6.0E-20 T 31-10-2018 IPR013783 Immunoglobulin-like fold TK0977 428e659255ac0a894d9b5072caea3a62 765 SMART SM00642 295 684 5.0E-105 T 31-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 TK0977 428e659255ac0a894d9b5072caea3a62 765 Gene3D G3DSA:3.20.20.80 291 685 5.1E-121 T 31-10-2018 TK0043 0a51f55f92a6ec5a9a4b4bd466bbf096 158 PIRSF PIRSF018660 6 158 6.1E-19 T 31-10-2018 IPR009205 Predicted archaeal flagellar protein C TK0043 0a51f55f92a6ec5a9a4b4bd466bbf096 158 Pfam PF05377 Flagella accessory protein C (FlaC) 49 102 4.6E-21 T 31-10-2018 IPR009205 Predicted archaeal flagellar protein C TK0043 0a51f55f92a6ec5a9a4b4bd466bbf096 158 Gene3D G3DSA:1.20.5.340 17 142 4.0E-6 T 31-10-2018 TK0937 278b3381b8ac4e953c37c5e9ebe584a3 767 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 465 688 2.6E-27 T 31-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit TK0937 278b3381b8ac4e953c37c5e9ebe584a3 767 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 144 405 2.5E-57 T 31-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit TK0937 278b3381b8ac4e953c37c5e9ebe584a3 767 TIGRFAM TIGR02123 TRAP_fused: TRAP transporter, 4TM/12TM fusion protein 61 435 6.8E-111 T 31-10-2018 IPR011853 TRAP C4-dicarboxylate transport system permease, fused DctM-DctQ TK1228 ee402afeec6659e05c4805736546b228 419 Pfam PF04055 Radical SAM superfamily 123 287 2.9E-27 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TK1228 ee402afeec6659e05c4805736546b228 419 SMART SM00729 115 333 4.5E-14 T 31-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TK1228 ee402afeec6659e05c4805736546b228 419 Gene3D G3DSA:3.20.20.70 113 357 2.5E-37 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TK1228 ee402afeec6659e05c4805736546b228 419 SUPERFAMILY SSF102114 111 333 6.54E-39 T 31-10-2018 TK0621 dc35f0e37fda69791b021b5c7f920ec1 76 Pfam PF13244 Domain of unknown function (DUF4040) 12 73 1.8E-10 T 31-10-2018 IPR025383 Domain of unknown function DUF4040 TK1941 b320732491a4cafb40cc983d0e9e4cb2 213 Pfam PF04254 Protein of unknown function (DUF432) 51 165 1.7E-28 T 31-10-2018 IPR007366 Protein of unknown function DUF432 TK1941 b320732491a4cafb40cc983d0e9e4cb2 213 PIRSF PIRSF019202 1 213 3.2E-48 T 31-10-2018 IPR007366 Protein of unknown function DUF432 TK1769 3dc8b0c548094c5381d4018d85ba68cf 341 SUPERFAMILY SSF159071 256 340 3.79E-18 T 31-10-2018 TK1769 3dc8b0c548094c5381d4018d85ba68cf 341 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 10 77 7.5E-25 T 31-10-2018 IPR002831 Transcription regulator TrmB, N-terminal TK1769 3dc8b0c548094c5381d4018d85ba68cf 341 Gene3D G3DSA:1.10.10.10 3 101 1.4E-29 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TK1769 3dc8b0c548094c5381d4018d85ba68cf 341 SUPERFAMILY SSF46785 4 95 1.47E-9 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TK1769 3dc8b0c548094c5381d4018d85ba68cf 341 Pfam PF11495 Archaeal transcriptional regulator TrmB 112 339 1.5E-58 T 31-10-2018 IPR021586 Transcription regulator TrmB, C-terminal TK0790 88404be35d1e05e34e9fcbee95a18c36 144 PIRSF PIRSF006595 1 144 1.4E-51 T 31-10-2018 IPR005369 Uncharacterised protein family UPF0179 TK0790 88404be35d1e05e34e9fcbee95a18c36 144 Hamap MF_00498 UPF0179 protein . 2 141 23.219 T 31-10-2018 IPR005369 Uncharacterised protein family UPF0179 TK0790 88404be35d1e05e34e9fcbee95a18c36 144 Pfam PF03684 Uncharacterised protein family (UPF0179) 4 139 9.9E-43 T 31-10-2018 IPR005369 Uncharacterised protein family UPF0179 TK0790 88404be35d1e05e34e9fcbee95a18c36 144 ProDom PD016182 UPF0179 TK0790 TV1250 PAE0681 PF1381 AF2154 MA3685 VNG1401C MJ1627 PH1477 3 143 1.0E-75 T 31-10-2018 IPR005369 Uncharacterised protein family UPF0179 TK1870 fa14e3c9f47b77308c83567349fec5c2 197 SUPERFAMILY SSF109755 2 197 2.72E-38 T 31-10-2018 TK1870 fa14e3c9f47b77308c83567349fec5c2 197 Gene3D G3DSA:1.20.58.220 1 197 1.7E-33 T 31-10-2018 IPR038078 PhoU-like domain superfamily TK1870 fa14e3c9f47b77308c83567349fec5c2 197 Pfam PF01895 PhoU domain 16 96 5.1E-8 T 31-10-2018 IPR026022 PhoU domain TK1870 fa14e3c9f47b77308c83567349fec5c2 197 Pfam PF01895 PhoU domain 113 187 4.1E-11 T 31-10-2018 IPR026022 PhoU domain TK0164 ab91f4bb9d5e5d0e3bbc722d38b13a8e 573 Pfam PF08308 PEGA domain 449 515 5.8E-19 T 31-10-2018 IPR013229 PEGA TK2027 ff9de874e1d7566fba97f9f3797949d0 255 Pfam PF01061 ABC-2 type transporter 35 210 1.8E-16 T 31-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 TK2027 ff9de874e1d7566fba97f9f3797949d0 255 PIRSF PIRSF006648 1 245 7.4E-22 T 31-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 TK0518 260df1cf1c26a88ab08a3b962278e3d3 150 Gene3D G3DSA:3.40.50.1000 8 143 2.1E-8 T 31-10-2018 IPR023214 HAD superfamily TK0518 260df1cf1c26a88ab08a3b962278e3d3 150 SUPERFAMILY SSF56784 12 132 1.52E-11 T 31-10-2018 IPR036412 HAD-like superfamily TK1013 ae1406314b1050680501cc9d6c8f3391 67 Pfam PF01954 Protein of unknown function DUF104 1 59 1.3E-13 T 31-10-2018 IPR008203 Uncharacterised protein family UPF0165 TK2028 d6fd9c168652d0778f44da5f18423447 272 Pfam PF01061 ABC-2 type transporter 37 227 7.4E-17 T 31-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 TK2028 d6fd9c168652d0778f44da5f18423447 272 PRINTS PR00164 ABC-2 type transport system membrane protein signature 186 205 8.3E-9 T 31-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 TK2028 d6fd9c168652d0778f44da5f18423447 272 PRINTS PR00164 ABC-2 type transport system membrane protein signature 149 173 8.3E-9 T 31-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 TK2028 d6fd9c168652d0778f44da5f18423447 272 PRINTS PR00164 ABC-2 type transport system membrane protein signature 206 225 8.3E-9 T 31-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 TK2028 d6fd9c168652d0778f44da5f18423447 272 PIRSF PIRSF006648 24 262 3.4E-18 T 31-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 TK1220 ee66d38282ed19fd968c6138311964bb 495 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 151 172 1.1E-7 T 31-10-2018 TK1220 ee66d38282ed19fd968c6138311964bb 495 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 78 103 1.1E-7 T 31-10-2018 TK1220 ee66d38282ed19fd968c6138311964bb 495 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 309 321 1.1E-7 T 31-10-2018 TK1220 ee66d38282ed19fd968c6138311964bb 495 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 216 237 1.1E-7 T 31-10-2018 TK1220 ee66d38282ed19fd968c6138311964bb 495 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 238 264 1.1E-7 T 31-10-2018 TK1220 ee66d38282ed19fd968c6138311964bb 495 Pfam PF00361 Proton-conducting membrane transporter 129 416 6.3E-64 T 31-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TK1654 fdb0e0aa5c693165f4b5c4b23546ca63 99 Gene3D G3DSA:1.10.10.10 1 99 2.1E-23 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TK1654 fdb0e0aa5c693165f4b5c4b23546ca63 99 Pfam PF03551 Transcriptional regulator PadR-like family 14 83 2.0E-16 T 31-10-2018 IPR005149 Transcription regulator PadR, N-terminal TK1654 fdb0e0aa5c693165f4b5c4b23546ca63 99 SUPERFAMILY SSF46785 3 97 1.49E-25 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TK0822 cba0590a976471c08654b4a8e4b95775 245 Pfam PF05763 Protein of unknown function (DUF835) 110 228 6.6E-28 T 31-10-2018 IPR008553 Domain of unknown function DUF835 TK1009 74d4edde3826ed04579d47cfca3fd24d 828 Gene3D G3DSA:3.40.50.300 573 717 2.7E-10 T 31-10-2018 TK1009 74d4edde3826ed04579d47cfca3fd24d 828 Gene3D G3DSA:3.40.50.300 403 506 8.5E-10 T 31-10-2018 TK1009 74d4edde3826ed04579d47cfca3fd24d 828 SMART SM00382 417 714 1.9E-4 T 31-10-2018 IPR003593 AAA+ ATPase domain TK1009 74d4edde3826ed04579d47cfca3fd24d 828 SUPERFAMILY SSF52540 405 775 1.32E-18 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK1009 74d4edde3826ed04579d47cfca3fd24d 828 Pfam PF07728 AAA domain (dynein-related subfamily) 624 704 7.4E-10 T 31-10-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 TK1009 74d4edde3826ed04579d47cfca3fd24d 828 Pfam PF07728 AAA domain (dynein-related subfamily) 421 473 2.6E-7 T 31-10-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 TK1009 74d4edde3826ed04579d47cfca3fd24d 828 SUPERFAMILY SSF69322 14 304 1.96E-5 T 31-10-2018 TK2036 a02d74795ea552ae7240cf6cd5deb584 275 SUPERFAMILY SSF103481 38 133 2.88E-15 T 31-10-2018 TK2036 a02d74795ea552ae7240cf6cd5deb584 275 SUPERFAMILY SSF103481 182 272 2.09E-7 T 31-10-2018 TK2036 a02d74795ea552ae7240cf6cd5deb584 275 Pfam PF00892 EamA-like transporter family 144 271 3.8E-16 T 31-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TK2036 a02d74795ea552ae7240cf6cd5deb584 275 Pfam PF00892 EamA-like transporter family 6 130 1.3E-20 T 31-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TK2023 ebc2d85ac8dea1d13381734a9b845098 246 PIRSF PIRSF019322 2 245 2.6E-91 T 31-10-2018 IPR016757 Uncharacterised conserved protein UCP019322 TK2023 ebc2d85ac8dea1d13381734a9b845098 246 Pfam PF09883 Uncharacterized protein conserved in archaea (DUF2110) 6 235 1.2E-75 T 31-10-2018 IPR016757 Uncharacterised conserved protein UCP019322 TK0050 c2423febe83222f797c173b1df0dd947 664 Gene3D G3DSA:2.60.40.10 453 562 2.8E-5 T 31-10-2018 IPR013783 Immunoglobulin-like fold TK1180 a1285ab70a64a6acf78337b54292f452 277 Gene3D G3DSA:1.25.40.10 19 208 1.6E-9 T 31-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TK0115 f9f0854c416538953bde1cc638d1e635 538 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 33 435 1.0E-76 T 31-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 TK0115 f9f0854c416538953bde1cc638d1e635 538 Gene3D G3DSA:1.20.1730.10 22 509 2.3E-92 T 31-10-2018 IPR038377 Sodium/glucose symporter superfamily TK0115 f9f0854c416538953bde1cc638d1e635 538 Pfam PF00474 Sodium:solute symporter family 33 435 7.1E-84 T 31-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 TK2095 17fc031e7eb362d5d80c47de67b48020 161 Gene3D G3DSA:1.20.1260.10 6 154 2.6E-33 T 31-10-2018 IPR012347 Ferritin-like TK2095 17fc031e7eb362d5d80c47de67b48020 161 SUPERFAMILY SSF47240 12 154 4.32E-28 T 31-10-2018 IPR009078 Ferritin-like superfamily TK2095 17fc031e7eb362d5d80c47de67b48020 161 Pfam PF02915 Rubrerythrin 16 152 2.2E-18 T 31-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 TK1242 cd2ae8e5788fb1827ada384f31fdb897 131 Gene3D G3DSA:2.30.30.110 23 131 1.0E-9 T 31-10-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor TK1242 cd2ae8e5788fb1827ada384f31fdb897 131 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 3 131 3.2E-16 T 31-10-2018 IPR003477 mRNA interferase PemK-like GO:0003677 TK1242 cd2ae8e5788fb1827ada384f31fdb897 131 SUPERFAMILY SSF50118 2 129 5.45E-8 T 31-10-2018 TK0358 7835036d034fcd8287254672513cd904 482 SUPERFAMILY SSF103365 5 482 2.09E-184 T 31-10-2018 IPR036025 tRNA-splicing ligase RtcB-like superfamily GO:0006396|GO:0008452 Reactome: R-HSA-6784531 TK0358 7835036d034fcd8287254672513cd904 482 Gene3D G3DSA:3.90.1860.10 3 482 9.5E-227 T 31-10-2018 IPR036025 tRNA-splicing ligase RtcB-like superfamily GO:0006396|GO:0008452 Reactome: R-HSA-6784531 TK0358 7835036d034fcd8287254672513cd904 482 Pfam PF01139 tRNA-splicing ligase RtcB 48 482 3.4E-181 T 31-10-2018 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 TK1844 1b359815b227eee6ba594ccbdbd94b47 141 PIRSF PIRSF018938 1 141 6.9E-53 T 31-10-2018 IPR016740 Uncharacterised conserved protein UCP018938 TK0074 db0748599c6aafc2e249b134d60bbf3d 588 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 111 249 2.1E-15 T 31-10-2018 TK0074 db0748599c6aafc2e249b134d60bbf3d 588 Gene3D G3DSA:2.60.120.200 57 255 2.4E-19 T 31-10-2018 TK0074 db0748599c6aafc2e249b134d60bbf3d 588 SUPERFAMILY SSF49899 50 255 1.55E-20 T 31-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily TK1780 691fe01c14eacecf113a90f31b46309a 121 Gene3D G3DSA:1.10.10.1150 41 104 3.0E-8 T 31-10-2018 TK1780 691fe01c14eacecf113a90f31b46309a 121 Pfam PF05402 Coenzyme PQQ synthesis protein D (PqqD) 44 102 2.9E-15 T 31-10-2018 IPR008792 Coenzyme PQQ synthesis D TK2044 eddf04f0922c84801d5a94aae82d227c 203 Gene3D G3DSA:3.40.50.11570 2 202 4.2E-46 T 31-10-2018 TK2044 eddf04f0922c84801d5a94aae82d227c 203 Pfam PF03192 Pyrococcus protein of unknown function, DUF257 5 201 3.0E-61 T 31-10-2018 IPR005489 Protein of unknown function DUF257 TK2294 7f5ef4bf30f7bd49bd025f1441cf7ec9 222 PIRSF PIRSF016179 1 222 9.1E-100 T 31-10-2018 IPR005266 Uncharacterised protein family UPF0128 TK2294 7f5ef4bf30f7bd49bd025f1441cf7ec9 222 ProDom PD023377 UPF0128 PYRAB08320 PH1314 PF1488 MJ1463 AQ_756 1 222 5.0E-118 T 31-10-2018 IPR005266 Uncharacterised protein family UPF0128 TK2294 7f5ef4bf30f7bd49bd025f1441cf7ec9 222 Hamap MF_00264 UPF0128 protein . 1 222 139.778 T 31-10-2018 IPR005266 Uncharacterised protein family UPF0128 TK2294 7f5ef4bf30f7bd49bd025f1441cf7ec9 222 Pfam PF03673 Uncharacterised protein family (UPF0128) 1 222 8.3E-109 T 31-10-2018 IPR005266 Uncharacterised protein family UPF0128 TK2294 7f5ef4bf30f7bd49bd025f1441cf7ec9 222 TIGRFAM TIGR00703 TIGR00703: TIGR00703 family protein 1 222 3.3E-99 T 31-10-2018 IPR005266 Uncharacterised protein family UPF0128 TK1175 a8d692acf8be764e26d6b9a411e81605 128 PIRSF PIRSF004985 1 120 1.7E-38 T 31-10-2018 IPR014428 Holliday junction resolvase Hjc, archaeal TK1175 a8d692acf8be764e26d6b9a411e81605 128 Hamap MF_01490 Holliday junction resolvase Hjc [hjc]. 2 124 37.761 T 31-10-2018 IPR014428 Holliday junction resolvase Hjc, archaeal TK1175 a8d692acf8be764e26d6b9a411e81605 128 SUPERFAMILY SSF52980 3 113 5.63E-30 T 31-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 TK1175 a8d692acf8be764e26d6b9a411e81605 128 ProDom PD015874 RESOLVASE HOLLIDAY JUNCTION ARCHAEAL HOLLIDAY-JUNCTION TYPE MJ0497 ORF-C21_024 PF1503 NEQ424 10 90 2.0E-40 T 31-10-2018 IPR014428 Holliday junction resolvase Hjc, archaeal TK1175 a8d692acf8be764e26d6b9a411e81605 128 Pfam PF01870 Archaeal holliday junction resolvase (hjc) 9 93 3.8E-28 T 31-10-2018 IPR002732 Holliday junction resolvase Hjc TK1175 a8d692acf8be764e26d6b9a411e81605 128 Gene3D G3DSA:3.40.1350.10 2 128 5.5E-38 T 31-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 TK0284 a8c42a4b439b5a7c8bc3e8e8631a9070 187 Pfam PF00881 Nitroreductase family 8 165 8.7E-30 T 31-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 TK0284 a8c42a4b439b5a7c8bc3e8e8631a9070 187 SUPERFAMILY SSF55469 1 187 1.18E-47 T 31-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 TK0284 a8c42a4b439b5a7c8bc3e8e8631a9070 187 Gene3D G3DSA:3.40.109.10 1 185 1.0E-49 T 31-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 TK0121 04fcff67c42b2839c831815d4207c9e8 98 Pfam PF04324 BFD-like [2Fe-2S] binding domain 10 62 3.0E-15 T 31-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain TK0121 04fcff67c42b2839c831815d4207c9e8 98 Gene3D G3DSA:1.10.10.1100 1 71 1.1E-23 T 31-10-2018 TK1238 f79e72ea67123d7427d56e5d7c77c3a2 74 SUPERFAMILY SSF141004 10 71 3.27E-25 T 31-10-2018 TK0646 e43993f4948d99f994f79281f215e6ef 111 Gene3D G3DSA:1.10.10.1220 1 88 8.7E-41 T 31-10-2018 TK1705 5252300b753157c363f7c2ddb7c37747 198 Pfam PF06510 Protein of unknown function (DUF1102) 39 185 3.5E-59 T 31-10-2018 IPR009482 Protein of unknown function DUF1102 TK2137 0d03edc4eb556e1780a33c7567ef1cac 276 Gene3D G3DSA:3.40.50.300 1 241 6.7E-45 T 31-10-2018 TK2137 0d03edc4eb556e1780a33c7567ef1cac 276 SUPERFAMILY SSF52540 2 239 5.04E-42 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK2137 0d03edc4eb556e1780a33c7567ef1cac 276 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 4 221 8.8E-18 T 31-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain TK1249 4d2f4c501b80ef6a304ffb81a8cb6da6 386 Pfam PF04412 Protein of unknown function (DUF521) 1 383 1.2E-150 T 31-10-2018 IPR007506 Aconitase X catalytic domain, putative TK2267 76abc3af1dd80761d807dbeafef20f55 87 Pfam PF01169 Uncharacterized protein family UPF0016 5 79 1.4E-22 T 31-10-2018 IPR001727 Gdt1 family TK0623 11a9718b10b4b1436346a9606c6892d1 135 Pfam PF04039 Domain related to MnhB subunit of Na+/H+ antiporter 6 122 3.9E-26 T 31-10-2018 IPR007182 Na+/H+ antiporter MnhB subunit-related protein TK0941 081a83c26d769507b909d69f18fed3f5 281 Pfam PF12679 ABC-2 family transporter protein 6 280 6.8E-39 T 31-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 TK1913 70ab48c6759cad9c34e54c92a4ce95e1 111 Gene3D G3DSA:1.10.10.10 2 110 5.8E-34 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TK1913 70ab48c6759cad9c34e54c92a4ce95e1 111 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 13 84 6.4E-10 T 31-10-2018 IPR002831 Transcription regulator TrmB, N-terminal TK1913 70ab48c6759cad9c34e54c92a4ce95e1 111 SUPERFAMILY SSF46785 4 103 7.56E-16 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TK0918 feb5fb6ba4cb6aa21031545e56f77fe0 161 Pfam PF11848 Domain of unknown function (DUF3368) 113 157 3.9E-16 T 31-10-2018 IPR021799 Protein of unknown function DUF3368 TK0619 e57673f3726674b0be3aed5ddbc510d8 90 Pfam PF04066 Multiple resistance and pH regulation protein F (MrpF / PhaF) 35 87 4.1E-15 T 31-10-2018 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 TK1451 d0394da1466013a3f753c9bf5c2033fc 151 Gene3D G3DSA:3.30.1440.10 2 149 2.9E-45 T 31-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1451 d0394da1466013a3f753c9bf5c2033fc 151 SUPERFAMILY SSF55282 7 149 1.97E-42 T 31-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TK1451 d0394da1466013a3f753c9bf5c2033fc 151 Pfam PF01877 RNA binding 9 131 8.2E-39 T 31-10-2018 IPR002739 Uncharacterised protein family UPF0201 TK1331 34d8808572060220d5b34113cf98dbf8 80 SUPERFAMILY SSF54909 1 77 1.47E-17 T 31-10-2018 IPR011008 Dimeric alpha-beta barrel TK1331 34d8808572060220d5b34113cf98dbf8 80 Gene3D G3DSA:3.30.70.920 1 73 3.1E-22 T 31-10-2018 TK1331 34d8808572060220d5b34113cf98dbf8 80 Pfam PF01037 Lrp/AsnC ligand binding domain 6 77 1.2E-16 T 31-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain TK0857 527779fbebec21a3d1f8ddf00ebec757 231 TIGRFAM TIGR00317 cobS: cobalamin 5'-phosphate synthase 2 223 1.3E-48 T 31-10-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 TK0857 527779fbebec21a3d1f8ddf00ebec757 231 Pfam PF02654 Cobalamin-5-phosphate synthase 5 221 2.1E-42 T 31-10-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 TK0857 527779fbebec21a3d1f8ddf00ebec757 231 Hamap MF_00719 Adenosylcobinamide-GDP ribazoletransferase [cobS]. 1 231 31.728 T 31-10-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 TK1714 946a82a9536c36913f405a92ba18478c 323 Pfam PF00535 Glycosyl transferase family 2 5 130 1.4E-31 T 31-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TK1714 946a82a9536c36913f405a92ba18478c 323 Gene3D G3DSA:3.90.550.10 1 248 7.1E-47 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TK1714 946a82a9536c36913f405a92ba18478c 323 SUPERFAMILY SSF53448 3 217 1.59E-51 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TK0797 e9ce49ac56391d10177b04f2fc4ff418 414 PIRSF PIRSF018863 1 414 4.3E-182 T 31-10-2018 IPR014496 Uncharacterised conserved protein UCP018863 TK0797 e9ce49ac56391d10177b04f2fc4ff418 414 Pfam PF04409 Protein of unknown function (DUF530) 6 255 3.4E-25 T 31-10-2018 IPR007503 Protein of unknown function DUF530 TK1395 0ac928a497ea93e5a0f8f34ec01d5f2e 653 SUPERFAMILY SSF52540 1 411 2.67E-19 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK1395 0ac928a497ea93e5a0f8f34ec01d5f2e 653 Pfam PF13175 AAA ATPase domain 1 409 2.4E-71 T 31-10-2018 TK0856 2fae1c4afa3eef50de813f0bf4a08e3b 191 SUPERFAMILY SSF53448 2 173 2.21E-20 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TK0856 2fae1c4afa3eef50de813f0bf4a08e3b 191 Gene3D G3DSA:3.90.550.10 2 176 1.6E-29 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TK0856 2fae1c4afa3eef50de813f0bf4a08e3b 191 Pfam PF12804 MobA-like NTP transferase domain 3 114 3.1E-14 T 31-10-2018 IPR025877 MobA-like NTP transferase TK1659 e2628ed8bdc40226b40870fe01d624b7 216 TIGRFAM TIGR00427 TIGR00427: membrane protein, MarC family 7 210 1.9E-60 T 31-10-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 TK1659 e2628ed8bdc40226b40870fe01d624b7 216 Pfam PF01914 MarC family integral membrane protein 9 214 1.5E-59 T 31-10-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 TK1225 e7d161c94ccd3bc6ab51aceb73690dac 84 Pfam PF04066 Multiple resistance and pH regulation protein F (MrpF / PhaF) 29 81 4.0E-19 T 31-10-2018 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 TK1189 ab734d8899901fe59923b8e20d21399c 257 Pfam PF02673 Bacitracin resistance protein BacA 8 248 3.2E-24 T 31-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 TK0108 3303591d5cc616f4e34e6eee466d5fc7 200 Pfam PF09622 Putative integral membrane protein (DUF2391) 64 195 1.0E-10 T 31-10-2018 IPR024464 Protein of unknown function DUF2391 TK1241 0ec8ad4a51ad9f51a4ee763be1c53e31 186 SUPERFAMILY SSF48371 30 149 6.24E-15 T 31-10-2018 IPR016024 Armadillo-type fold TK1241 0ec8ad4a51ad9f51a4ee763be1c53e31 186 Gene3D G3DSA:1.25.10.10 15 164 6.0E-10 T 31-10-2018 IPR011989 Armadillo-like helical TK0742 983f69c467d191468ebfce4144d2d80d 188 Pfam PF06197 Protein of unknown function (DUF998) 10 180 2.1E-28 T 31-10-2018 IPR009339 Protein of unknown function DUF998 TK2296 8f98ac640b8f2e42a2c11b726765625d 266 Pfam PF04055 Radical SAM superfamily 29 183 6.2E-9 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TK2296 8f98ac640b8f2e42a2c11b726765625d 266 Gene3D G3DSA:3.20.20.70 24 259 2.5E-5 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TK2296 8f98ac640b8f2e42a2c11b726765625d 266 SUPERFAMILY SSF102114 31 225 3.34E-7 T 31-10-2018 TK0215 8b3e69023bcd57a1816210700cb5ac85 576 Pfam PF16286 Domain of unknown function (DUF4932) 64 367 1.4E-20 T 31-10-2018 IPR032560 Protein of unknown function DUF4932 TK0235 7ce1bf417e79d2609b4bdbf53a00557f 403 Pfam PF07690 Major Facilitator Superfamily 11 348 3.1E-16 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TK0235 7ce1bf417e79d2609b4bdbf53a00557f 403 Gene3D G3DSA:1.20.1250.20 5 380 8.9E-31 T 31-10-2018 TK0235 7ce1bf417e79d2609b4bdbf53a00557f 403 SUPERFAMILY SSF103473 10 377 1.7E-31 T 31-10-2018 IPR036259 MFS transporter superfamily TK1053 509c090f4dc5d49fcd998e6fb056c10f 243 Pfam PF01925 Sulfite exporter TauE/SafE 7 241 1.4E-56 T 31-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 TK1977 a910aa3afc420f0cb356e4b401b7314c 320 Pfam PF01384 Phosphate transporter family 19 307 4.9E-69 T 31-10-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 TK0009 3413dec97db11d382e854f8a70bce93b 416 Gene3D G3DSA:1.25.40.10 293 408 1.4E-7 T 31-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TK0009 3413dec97db11d382e854f8a70bce93b 416 Gene3D G3DSA:1.25.40.10 4 234 1.8E-11 T 31-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TK0691 1e591c7628111072125bfb524b6b9dfd 359 Pfam PF05763 Protein of unknown function (DUF835) 222 354 2.3E-36 T 31-10-2018 IPR008553 Domain of unknown function DUF835 TK2194 d396e262578c14044e5760cf39004065 207 Gene3D G3DSA:1.10.1760.20 3 193 1.8E-21 T 31-10-2018 TK0846 f84bbb3aa03e3f39a44315413fd86f1b 194 Pfam PF01955 Adenosylcobinamide amidohydrolase 8 180 2.7E-45 T 31-10-2018 IPR002808 Adenosylcobinamide amidohydrolase, CbiZ TK0692 c8495ff9f885836400a1de45199c1ca6 234 Pfam PF12698 ABC-2 family transporter protein 48 227 5.6E-9 T 31-10-2018 TK1560 fc74ed211a7d7dad7295d5588c8cc2fe 374 Gene3D G3DSA:1.20.1530.20 1 374 4.2E-88 T 31-10-2018 IPR038770 Sodium/solute symporter superfamily TK1560 fc74ed211a7d7dad7295d5588c8cc2fe 374 Pfam PF00999 Sodium/hydrogen exchanger family 8 371 1.5E-69 T 31-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 TK0446 6e66a9ee7f37f8d91d85a18c930af025 233 Pfam PF12705 PD-(D/E)XK nuclease superfamily 62 222 1.0E-4 T 31-10-2018 IPR038726 PD-(D/E)XK endonuclease-like domain, AddAB-type TK0446 6e66a9ee7f37f8d91d85a18c930af025 233 Gene3D G3DSA:3.90.320.10 18 225 2.3E-20 T 31-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal TK0006 350c6df0b8342c4a3e90a987fdbd350b 91 Pfam PF10130 PIN domain 8 89 6.8E-11 T 31-10-2018 IPR002716 PIN domain TK2091 a54fe44ebd6e1648dc5b33c51c7a094c 426 SUPERFAMILY SSF56762 18 381 1.7E-104 T 31-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TK2091 a54fe44ebd6e1648dc5b33c51c7a094c 426 Gene3D G3DSA:1.10.645.20 9 381 4.8E-121 T 31-10-2018 IPR038290 NADH-quinone oxidoreductase, subunit D superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TK2091 a54fe44ebd6e1648dc5b33c51c7a094c 426 Pfam PF00374 Nickel-dependent hydrogenase 47 115 2.4E-13 T 31-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 TK2091 a54fe44ebd6e1648dc5b33c51c7a094c 426 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 122 381 2.9E-56 T 31-10-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TK1043 95e1df9fcf7d71ff6eaaa83188bff7e9 217 Pfam PF13349 Putative adhesin 82 215 4.4E-7 T 31-10-2018 IPR025164 Putative adhesin TK0500 daf13da4a1c4b52739570db571be7c14 75 Pfam PF10049 Protein of unknown function (DUF2283) 2 49 5.7E-19 T 31-10-2018 IPR019270 Protein of unknown function DUF2283 TK2258 2ee668d519d756778c2e98e5c78b674f 259 Pfam PF01435 Peptidase family M48 54 248 9.1E-23 T 31-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 TK2258 2ee668d519d756778c2e98e5c78b674f 259 Gene3D G3DSA:3.30.2010.10 49 132 7.3E-17 T 31-10-2018 TK0947 a1b416f01da56631ca79f1deba05da5f 393 SUPERFAMILY SSF48452 16 386 1.57E-11 T 31-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TK0947 a1b416f01da56631ca79f1deba05da5f 393 Gene3D G3DSA:1.25.40.10 267 385 6.0E-6 T 31-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TK1074 9f95dd8075a68b99812120a187e9151d 130 PIRSF PIRSF014543 1 124 9.9E-55 T 31-10-2018 IPR016621 Uncharacterised conserved protein UCP014543 TK1074 9f95dd8075a68b99812120a187e9151d 130 Pfam PF12646 Domain of unknown function (DUF3783) 56 111 4.1E-13 T 31-10-2018 IPR016621 Uncharacterised conserved protein UCP014543 TK0053 84a8a9712f99723b6e0187080abb5c47 400 Gene3D G3DSA:1.20.120.1220 55 176 3.9E-12 T 31-10-2018 TK0053 84a8a9712f99723b6e0187080abb5c47 400 Pfam PF06819 Archaeal Peptidase A24 C-terminal Domain 256 364 3.0E-38 T 31-10-2018 IPR009639 Peptidase A24A-predicted, C-terminal archaea TK0609 a64c2c88b7603d932574559aff80cd4e 712 Gene3D G3DSA:2.60.40.2050 293 362 3.1E-21 T 31-10-2018 TK0609 a64c2c88b7603d932574559aff80cd4e 712 Gene3D G3DSA:2.60.40.2050 170 292 1.1E-32 T 31-10-2018 TK0609 a64c2c88b7603d932574559aff80cd4e 712 Gene3D G3DSA:1.20.120.870 530 671 9.2E-45 T 31-10-2018 TK1661 61d9b3657d4b87a6b19d98bcdff46977 250 Pfam PF09874 Predicted membrane protein (DUF2101) 27 230 4.1E-96 T 31-10-2018 IPR018663 Protein of unknown function DUF2101, membrane TK0385 8fdff1c137ed86486c3eb54bfe1dc1de 628 SUPERFAMILY SSF49464 222 293 3.37E-5 T 31-10-2018 IPR008969 Carboxypeptidase-like, regulatory domain superfamily TK0840 77dd856c11c0f146d1657bb74a8a48ef 231 Pfam PF00881 Nitroreductase family 57 230 5.4E-35 T 31-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 TK0840 77dd856c11c0f146d1657bb74a8a48ef 231 Gene3D G3DSA:3.40.109.10 25 230 1.0E-74 T 31-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 TK0840 77dd856c11c0f146d1657bb74a8a48ef 231 SUPERFAMILY SSF55469 51 229 3.87E-38 T 31-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 TK0840 77dd856c11c0f146d1657bb74a8a48ef 231 TIGRFAM TIGR03605 antibiot_sagB: SagB-type dehydrogenase domain 74 229 3.1E-46 T 31-10-2018 IPR020051 SagB-type dehydrogenase domain TK0231 76fcc9f2e995f3f423183dad22c17d84 238 PRINTS PR00164 ABC-2 type transport system membrane protein signature 93 118 1.0E-4 T 31-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 TK0231 76fcc9f2e995f3f423183dad22c17d84 238 PRINTS PR00164 ABC-2 type transport system membrane protein signature 183 202 1.0E-4 T 31-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 TK0231 76fcc9f2e995f3f423183dad22c17d84 238 PRINTS PR00164 ABC-2 type transport system membrane protein signature 163 182 1.0E-4 T 31-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 TK0231 76fcc9f2e995f3f423183dad22c17d84 238 Pfam PF01061 ABC-2 type transporter 13 205 8.2E-11 T 31-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 TK0794 1ba3bfee7ecd45b205f88a061b0c4028 476 Pfam PF10117 McrBC 5-methylcytosine restriction system component 62 402 1.7E-69 T 31-10-2018 IPR019292 5-methylcytosine restriction system component TK1245 ba25981c7ee779c297c8eeaaeb92220b 135 Pfam PF04021 Class III signal peptide 7 32 3.2E-9 T 31-10-2018 IPR007166 Class III signal peptide motif TK2092 f7f6a33b7d69089f853554cda2bb1524 328 Pfam PF00146 NADH dehydrogenase 15 322 4.3E-60 T 31-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TK0625 67aa6c9620050ed229e4d418732ace20 495 Pfam PF00361 Proton-conducting membrane transporter 117 379 6.3E-52 T 31-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TK0625 67aa6c9620050ed229e4d418732ace20 495 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 221 245 1.6E-7 T 31-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TK0625 67aa6c9620050ed229e4d418732ace20 495 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 153 177 1.6E-7 T 31-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TK0625 67aa6c9620050ed229e4d418732ace20 495 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 304 323 1.6E-7 T 31-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TK0625 67aa6c9620050ed229e4d418732ace20 495 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 123 142 1.6E-7 T 31-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TK2154 6067622f363ad10e51c262b2299d3359 90 Pfam PF03683 Uncharacterised protein family (UPF0175) 28 85 1.5E-16 T 31-10-2018 IPR005368 Uncharacterised protein family UPF0175 TK0003 1302cd89ae4b5769cfb3c478b16c6bc8 129 SUPERFAMILY SSF141322 64 126 9.02E-8 T 31-10-2018 TK0003 1302cd89ae4b5769cfb3c478b16c6bc8 129 Gene3D G3DSA:2.40.50.140 65 129 2.7E-16 T 31-10-2018 TK0003 1302cd89ae4b5769cfb3c478b16c6bc8 129 Pfam PF01957 NfeD-like C-terminal, partner-binding 18 126 5.4E-12 T 31-10-2018 IPR002810 NfeD-like, C-terminal domain TK0741 13d35eb70beaa81035b70d46efdf9e56 102 SUPERFAMILY SSF54909 2 69 9.91E-7 T 31-10-2018 IPR011008 Dimeric alpha-beta barrel TK1712 9fbc265b228d9bc8dd9ca5752a44c992 415 Pfam PF01943 Polysaccharide biosynthesis protein 9 279 1.3E-28 T 31-10-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 TK1712 9fbc265b228d9bc8dd9ca5752a44c992 415 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 330 409 1.3E-17 T 31-10-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain TK0172 9f4cec2c53f99c1791e70799fc8f99fa 386 Pfam PF04123 Domain of unknown function (DUF373) 1 344 3.2E-101 T 31-10-2018 IPR007254 Protein of unknown function DUF373 TK1855 e355c030540a88e0fc5b620c85a2d5b1 480 Pfam PF04415 Protein of unknown function (DUF515) 28 480 6.1E-215 T 31-10-2018 IPR007509 Protein of unknown function DUF515 TK0379 ab2e33c5f79143d1e5769b786ebd9ffa 381 Pfam PF05559 Protein of unknown function (DUF763) 4 335 9.8E-123 T 31-10-2018 IPR008482 Protein of unknown function DUF763 TK1480 dac56c726e7c02b0efd5c2d57e914448 356 Gene3D G3DSA:1.25.40.10 3 71 3.2E-8 T 31-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TK0501 4b77cee87f6aa4a1978086920e3062b3 90 Pfam PF14076 Domain of unknown function (DUF4258) 6 71 6.0E-11 T 31-10-2018 IPR025354 Protein of unknown function DUF4258 TK2216 f3a95627744c717c996b5e4de113cd36 279 Pfam PF05763 Protein of unknown function (DUF835) 137 271 9.4E-41 T 31-10-2018 IPR008553 Domain of unknown function DUF835 TK0111 682cda6b63923811d6a908c2d32e67f3 62 Pfam PF07754 Domain of unknown function (DUF1610) 13 36 2.8E-14 T 31-10-2018 IPR011668 Domain of unknown function DUF1610 TK0213 b976cfb83365d26153a69a0d795c80cc 86 Pfam PF03683 Uncharacterised protein family (UPF0175) 8 81 5.9E-26 T 31-10-2018 IPR005368 Uncharacterised protein family UPF0175 TK2098 f12c9014eda03d9cbe983d1d6fcc0fae 402 SUPERFAMILY SSF52540 55 303 4.19E-23 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK1423 88fc26147f601407fe2acbfde29c5dcb 58 Pfam PF04021 Class III signal peptide 2 27 2.0E-9 T 31-10-2018 IPR007166 Class III signal peptide motif TK1221 be41d8ee714a1565ee78703f468bcc70 114 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 5 111 4.7E-33 T 31-10-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like TK1561 418426ae0b684c805d7511f7ac0aab9f 203 Pfam PF01914 MarC family integral membrane protein 6 196 1.5E-30 T 31-10-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 TK1072 fd4c197ca9f4ddde28693a0dca71cde3 137 SUPERFAMILY SSF81593 11 126 3.85E-5 T 31-10-2018 TK1072 fd4c197ca9f4ddde28693a0dca71cde3 137 Gene3D G3DSA:1.20.120.330 4 128 8.8E-38 T 31-10-2018 TK1072 fd4c197ca9f4ddde28693a0dca71cde3 137 Pfam PF05168 HEPN domain 8 123 8.2E-28 T 31-10-2018 IPR007842 HEPN domain TK0652 edd130da336097ec6475dda792e8bf2e 269 Pfam PF02535 ZIP Zinc transporter 124 264 6.0E-19 T 31-10-2018 IPR003689 Zinc/iron permease GO:0016020|GO:0030001|GO:0046873|GO:0055085 TK2222 a56eccc4f4415a4dfcddf295a42d499d 418 SUPERFAMILY SSF52540 17 147 1.6E-11 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK2155 cb36d39d858779ffd4aed129af82269c 160 SUPERFAMILY SSF88723 2 117 2.26E-12 T 31-10-2018 IPR029060 PIN-like domain superfamily TK2155 cb36d39d858779ffd4aed129af82269c 160 Pfam PF11848 Domain of unknown function (DUF3368) 111 155 3.0E-9 T 31-10-2018 IPR021799 Protein of unknown function DUF3368 TK0922 f067428405a2bace7513108bc8ad31f1 78 Pfam PF10049 Protein of unknown function (DUF2283) 7 52 8.1E-17 T 31-10-2018 IPR019270 Protein of unknown function DUF2283 TK0776 7c5142798b64af93995e6f0ea885996d 418 SUPERFAMILY SSF52540 12 147 5.69E-10 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TK2086 0fbad7b07820d8ac74d7d05dd179415b 119 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 6 115 2.0E-25 T 31-10-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like TK1664 923c87e1914e059213c7ab61d62df6a8 829 Gene3D G3DSA:2.160.20.20 250 468 1.9E-5 T 31-10-2018 IPR012332 P22 tailspike-like, C-terminal domain superfamily TK1171 99db66b9742f1ae8750fca08448923f6 210 Gene3D G3DSA:3.40.50.300 1 199 6.6E-47 T 31-10-2018 TK1845 3fb58451b6acaad96cafb944882f7095 439 Pfam PF01882 Protein of unknown function DUF58 219 298 6.0E-23 T 31-10-2018 IPR002881 Domain of unknown function DUF58 TK1690 df11ab00e21fbf82f4a8f704fbbf8809 584 SUPERFAMILY SSF48239 34 485 7.0E-25 T 31-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid TK1690 df11ab00e21fbf82f4a8f704fbbf8809 584 Gene3D G3DSA:1.50.10.20 338 487 7.8E-7 T 31-10-2018 TK1690 df11ab00e21fbf82f4a8f704fbbf8809 584 Gene3D G3DSA:1.50.10.20 28 144 6.2E-13 T 31-10-2018 TK2048 c065970139ed5e4ee99624ae748af12d 992 SUPERFAMILY SSF50249 913 989 7.2E-6 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold TK0146 cfd021e54136f77cfa91169fe0d610d7 293 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 40 277 6.8E-9 T 31-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD TK1162 3e16a5b49262c9ce7780975f59935d4c 330 Pfam PF01594 AI-2E family transporter 10 322 2.4E-29 T 31-10-2018 IPR002549 Transmembrane protein TqsA-like TK1105 419b826772970cd1e619d461039277e8 219 Pfam PF02361 Cobalt transport protein 5 192 7.5E-28 T 31-10-2018 IPR003339 ABC/ECF transporter, transmembrane component TK0936 4af709ac4641c2815474d17b48746137 150 Pfam PF08905 Domain of unknown function (DUF1850) 43 120 9.5E-11 T 31-10-2018 IPR015001 Protein of unknown function DUF1850 TK1651 8ded49dbd7c7ebfaaacc6653cc12f384 136 Pfam PF09999 Uncharacterized protein conserved in archaea (DUF2240) 16 63 2.1E-5 T 31-10-2018 IPR018716 Protein of unknown function DUF2240 TK1678 e3dd3ad244b3420aec3c912d05d13139 500 SUPERFAMILY SSF82171 40 304 1.02E-6 T 31-10-2018 TK0569 c923a4d0724d3c67f41ada0316aec19a 358 TIGRFAM TIGR04288 CGP_CTERM: CGP-CTERM domain 338 357 1.0E-8 T 31-10-2018 IPR027552 CGP-CTERM domain TK0206 e67b78b40c820f7cf3eb654b5b5cc540 251 Gene3D G3DSA:3.40.50.300 1 251 5.6E-79 T 31-10-2018 TK0054 abba33a146d027c69232b93c915dbe6a 55 Pfam PF04021 Class III signal peptide 3 28 7.1E-10 T 31-10-2018 IPR007166 Class III signal peptide motif TK1040 50d11f764358054fd0a5098daad67bfb 59 SUPERFAMILY SSF47113 6 59 4.53E-7 T 31-10-2018 IPR009072 Histone-fold GO:0046982 TK1568 7a978e94aada598158fe9c00522e1c69 488 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 35 435 1.5E-61 T 31-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 TK1568 7a978e94aada598158fe9c00522e1c69 488 Pfam PF00474 Sodium:solute symporter family 35 431 4.5E-63 T 31-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 TK1568 7a978e94aada598158fe9c00522e1c69 488 Gene3D G3DSA:1.20.1730.10 23 487 8.7E-78 T 31-10-2018 IPR038377 Sodium/glucose symporter superfamily TK1092 c761a03a851eb9029d917bef47cfa93f 303 SUPERFAMILY SSF53795 103 172 3.97E-6 T 31-10-2018 TK1223 0c0e1f6a17b57558d4493533fcb1b6c5 94 Pfam PF13244 Domain of unknown function (DUF4040) 13 79 1.2E-18 T 31-10-2018 IPR025383 Domain of unknown function DUF4040 TK0985 214a1b74497e5240b92898167d0c5ed2 470 TIGRFAM TIGR04288 CGP_CTERM: CGP-CTERM domain 450 469 1.4E-8 T 31-10-2018 IPR027552 CGP-CTERM domain TK1578 4ed87150a9b4a894feb0876c11c293ad 348 Pfam PF12679 ABC-2 family transporter protein 4 345 1.3E-36 T 31-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 TK1187 e0c25a02fc0e1d0e42617dfe5e5e387d 378 Pfam PF05763 Protein of unknown function (DUF835) 229 368 4.8E-36 T 31-10-2018 IPR008553 Domain of unknown function DUF835 TK1856 837dd0d9ef902dc479118bbbfe18b456 110 TIGRFAM TIGR04076 TIGR04076: TIGR04076 family protein 1 96 1.6E-21 T 31-10-2018 IPR023811 Conserved hypothetical protein CHP04076 TK1258 fd4d0363a8da394421e89ca9b6bdbf7b 237 Pfam PF01940 Integral membrane protein DUF92 9 213 7.6E-54 T 31-10-2018 IPR002794 Protein of unknown function DUF92, TMEM19 GO:0016021 TK0660 6e3f8451e055720688f7c340831c6ee4 303 Pfam PF02653 Branched-chain amino acid transport system / permease component 12 264 1.1E-39 T 31-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TK1833 a9656eafa66e3da1797c8cf43ad75e4e 654 Pfam PF04312 Protein of unknown function (DUF460) 190 330 5.8E-50 T 31-10-2018 IPR007408 Protein of unknown function DUF460