locus-tag	class	description
BD01_0023	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
BD01_0027	ENOG4105C0M	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity)
BD01_0029	ENOG4107R76	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
BD01_0031	ENOG4105CX6	glutaminyL-tRNA synthetase
BD01_0039	ENOG4105DHP	deoxycytidine triphosphate deaminase
BD01_0044	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
BD01_0045	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
BD01_0048	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
BD01_0055	ENOG4108T9Q	UPF0278 protein
BD01_0058	ENOG4107RGW	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BD01_0059	ENOG4107QK8	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BD01_0069	ENOG4108JU3	Alkyl hydroperoxide reductase
BD01_0073	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
BD01_0076	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
BD01_0077	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
BD01_0079	ENOG4105CT4	transporter
BD01_0081	ENOG4105VXP	Protein of unknown function DUF86
BD01_0085	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
BD01_0086	ENOG4105UQX	Mate efflux family protein
BD01_0087	ENOG4105UQX	Mate efflux family protein
BD01_0095	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
BD01_0095	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
BD01_0098	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
BD01_0102	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BD01_0109	ENOG41080XS	Cobyrinic acid ac-diamide synthase
BD01_0110	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
BD01_0111	ENOG4105C45	hydrogenase expression formation protein (HypE)
BD01_0115	ENOG4105CQS	hydrogenase expression formation protein HypD
BD01_0116	ENOG4105WRB	Hydrogenase assembly chaperone hypC hupF
BD01_0119	ENOG41067SE	Tetr family transcriptional regulator
BD01_0120	ENOG4108IEG	Formate dehydrogenase Alpha subunit
BD01_0121	ENOG4105D3S	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
BD01_0122	ENOG4105D65	subunit l
BD01_0123	ENOG4108JPZ	Monovalent cation H antiporter subunit D
BD01_0124	ENOG4107TDF	Formate hydrogenlyase subunit 4
BD01_0125	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
BD01_0126	ENOG4108RG7	formate hydrogenlyase complex iron-sulfur subunit
BD01_0127	ENOG4105C47	NADH ubiquinone oxidoreductase 20 kda subunit
BD01_0130	ENOG41083NF	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
BD01_0144	ENOG4108ESU	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane (By similarity)
BD01_0145	ENOG4105E0A	ABC, transporter
BD01_0147	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
BD01_0150	ENOG4108Y83	glucose-6-phosphate isomerase
BD01_0153	ENOG410667J	hydrolase
BD01_0162	ENOG4105CIG	ABC transporter
BD01_0165	ENOG4108JJB	ABC transporter
BD01_0166	ENOG41082M7	Cobalt transport protein
BD01_0168	ENOG4105CFT	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import (By similarity)
BD01_0171	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
BD01_0177	ENOG4105CHM	Aminotransferase
BD01_0180	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
BD01_0187	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
BD01_0189	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
BD01_0193	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
BD01_0200	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
BD01_0208	ENOG4105DTT	CRISPR-associated helicase, cas3
BD01_0210	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
BD01_0211	ENOG4105ZHF	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
BD01_0213	ENOG4105CD5	CoA-binding domain protein
BD01_0217	ENOG4106K5Q	Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication (By similarity)
BD01_0224	ENOG4107XGZ	Hydrolase
BD01_0234	ENOG4105C5S	asparaginyl-tRNA synthetase
BD01_0237	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
BD01_0241	ENOG4105CH2	amidohydrolase
BD01_0251	ENOG4105BZR	domain protein
BD01_0254	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
BD01_0264	ENOG4105E3H	phosphoglycerate mutase
BD01_0267	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
BD01_0269	ENOG41087GE	Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity)
BD01_0270	ENOG4105DBV	ornithine carbamoyltransferase
BD01_0279	ENOG4108J9M	Transporter
BD01_0286	ENOG4108M14	stage v sporulation protein t
BD01_0287	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
BD01_0295	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
BD01_0297	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
BD01_0304	ENOG4105HDK	L-asparaginase
BD01_0305	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
BD01_0310	ENOG4105CPQ	Dehydrogenase
BD01_0311	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
BD01_0315	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
BD01_0316	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
BD01_0317	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
BD01_0325	ENOG4105EEI	dihydropteroate synthase
BD01_0326	ENOG4105F4G	Membrane
BD01_0334	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
BD01_0335	ENOG4105C22	threonyL-tRNA synthetase
BD01_0338	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
BD01_0339	ENOG4108Z0R	Transferase
BD01_0342	ENOG4105CN9	Peptidase m42 family protein
BD01_0346	ENOG4108JJB	ABC transporter
BD01_0347	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
BD01_0348	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
BD01_0350	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
BD01_0352	ENOG4107V9E	glucose-1-phosphate thymidylyltransferase
BD01_0354	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
BD01_0355	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BD01_0360	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
BD01_0365	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
BD01_0369	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
BD01_0373	ENOG4108V1U	phospholipid-binding protein
BD01_0382	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
BD01_0386	ENOG4108JPW	Aminotransferase
BD01_0389	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
BD01_0391	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
BD01_0393	ENOG4108JPZ	Monovalent cation H antiporter subunit D
BD01_0394	ENOG4108JPZ	Monovalent cation H antiporter subunit D
BD01_0395	ENOG4105MKQ	Monovalent cation H antiporter subunit C
BD01_0396	ENOG4105D65	subunit l
BD01_0398	ENOG4105KJM	monovalent cation h antiporter subunit g
BD01_0399	ENOG410684G	monovalent cation H antiporter subunit F
BD01_0400	ENOG4105SC1	monovalent cation H antiporter subunit E
BD01_0402	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
BD01_0405	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
BD01_0406	ENOG4108IJ1	Dehydrogenase
BD01_0410	ENOG4105C75	arginyL-tRNA synthetase
BD01_0423	ENOG4105DER	m42 family
BD01_0443	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
BD01_0447	ENOG4105C1A	potassium transporter peripheral membrane
BD01_0451	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
BD01_0453	ENOG4105DZH	s-adenosylmethionine synthetase (EC 2.5.1.6)
BD01_0455	ENOG4107RFY	SbcCD D subunit
BD01_0457	ENOG4105CHM	Aminotransferase
BD01_0461	ENOG4107XGZ	Hydrolase
BD01_0462	ENOG4105DIW	FeS assembly protein SUFB
BD01_0463	ENOG4105C3K	feS assembly ATPase SufC
BD01_0464	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
BD01_0466	ENOG4105KME	endoribonuclease L-psp
BD01_0469	ENOG4108ZPQ	MazG nucleotide pyrophosphohydrolase
BD01_0470	ENOG4108VVK	transcriptional Regulator, AsnC
BD01_0472	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
BD01_0477	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
BD01_0499	ENOG4108WBT	adenosyltransferase
BD01_0501	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
BD01_0502	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
BD01_0504	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
BD01_0505	ENOG4108R6K	riboflavin synthase, subunit alpha
BD01_0506	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
BD01_0511	ENOG4105C8V	SAICAR synthetase
BD01_0513	ENOG4105IQJ	Involved in biosynthesis of the thiamine precursor thiazole (By similarity)
BD01_0514	ENOG4105DWF	phosphomethylpyrimidine kinase
BD01_0515	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
BD01_0518	ENOG4108YZY	peptidylprolyl cis-trans isomerase
BD01_0519	ENOG4105C8N	cysteinyl-tRNA synthetase
BD01_0530	ENOG4105HF0	Membrane
BD01_0536	ENOG4105C5I	Dehydrogenase
BD01_0537	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
BD01_0541	ENOG4105D64	Mechanosensitive ion channel
BD01_0542	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
BD01_0544	ENOG4105KJJ	Uncharacterized ACR, COG1993
BD01_0545	ENOG4105WMR	Protein CrcB homolog
BD01_0551	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BD01_0554	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
BD01_0555	ENOG4108VVK	transcriptional Regulator, AsnC
BD01_0557	ENOG4105C3G	gtp-binding protein
BD01_0558	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
BD01_0569	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
BD01_0571	ENOG4105DXX	methyltransferase
BD01_0572	ENOG4105CIH	Imidazole acetol-phosphate transaminase
BD01_0573	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
BD01_0584	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
BD01_0585	ENOG4108K7V	UPF0284 protein
BD01_0589	ENOG4105EPU	Molybdenum cofactor synthesis domain protein
BD01_0592	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
BD01_0598	ENOG4105DCI	Phosphohydrolase
BD01_0600	ENOG4105KNA	-acetyltransferase
BD01_0601	ENOG4105D3R	alkyl hydroperoxide reductase
BD01_0602	ENOG4108J2R	molybdopterin oxidoreductase
BD01_0609	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
BD01_0614	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
BD01_0620	ENOG4105C11	sulfate adenylyltransferase), subunit 2
BD01_0633	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
BD01_0635	ENOG4105C5I	Dehydrogenase
BD01_0641	ENOG4107WZZ	SMC domain protein
BD01_0641	ENOG4107WZZ	SMC domain protein
BD01_0645	ENOG4105C8Q	Methyl-accepting chemotaxis
BD01_0648	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
BD01_0649	ENOG4105D0M	Protease HtpX homolog
BD01_0650	ENOG4105CE4	GlcNAc 6-P deacetylase
BD01_0651	ENOG4105K6S	Short-chain dehydrogenase reductase Sdr
BD01_0652	ENOG4105BZ8	glutamate synthase
BD01_0653	ENOG4105E0R	Deoxyhypusine synthase
BD01_0658	ENOG4105F4P	)-transporter
BD01_0662	ENOG4107Y03	Nitroreductase
BD01_0665	ENOG4108JPZ	Monovalent cation H antiporter subunit D
BD01_0666	ENOG4105SC1	monovalent cation H antiporter subunit E
BD01_0667	ENOG4108ZE9	Monovalent cation H antiporter subunit C
BD01_0671	ENOG410684G	monovalent cation H antiporter subunit F
BD01_0672	ENOG4108JPZ	Monovalent cation H antiporter subunit D
BD01_0673	ENOG4105D65	subunit l
BD01_0674	ENOG41090A1	ferritin
BD01_0676	ENOG4105CNW	domain protein
BD01_0677	ENOG4108RAC	Rubrerythrin
BD01_0678	ENOG4105VCQ	rubredoxin
BD01_0679	ENOG4108YZ8	Superoxide reductase
BD01_0692	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
BD01_0695	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
BD01_0696	ENOG4105E0C	molybdate abc transporter
BD01_0706	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
BD01_0707	ENOG4108JJB	ABC transporter
BD01_0708	ENOG4105VKD	bioY protein
BD01_0713	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
BD01_0714	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
BD01_0717	ENOG4105DP9	ABC transporter
BD01_0722	ENOG4105D9P	serine threonine protein kinase
BD01_0724	ENOG4105D9P	serine threonine protein kinase
BD01_0726	ENOG4105D9P	serine threonine protein kinase
BD01_0728	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
BD01_0729	ENOG4105C5S	asparaginyl-tRNA synthetase
BD01_0734	ENOG4105CJ3	phosphate transporter
BD01_0735	ENOG4107QJZ	Glycosyl transferase, family 2
BD01_0737	ENOG4107QRT	dEAD DEAH box helicase
BD01_0738	ENOG4105DC7	peptidase M24
BD01_0741	ENOG4108K3F	N(2),N(2)-dimethylguanosine tRNA methyltransferase
BD01_0745	ENOG4105UQX	Mate efflux family protein
BD01_0748	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
BD01_0749	ENOG4105VXP	Protein of unknown function DUF86
BD01_0754	ENOG4105VZ9	UPF0235 protein
BD01_0757	ENOG4105CEV	competence damage-inducible protein
BD01_0762	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
BD01_0765	ENOG4105CE1	Ferrous iron transport protein b
BD01_0770	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
BD01_0775	ENOG4105DSE	periplasmic solute binding protein
BD01_0777	ENOG4105UIB	(ABC) transporter
BD01_0778	ENOG4108JQ9	ABC transporter
BD01_0779	ENOG4105DIH	basic membrane
BD01_0781	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
BD01_0786	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
BD01_0793	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
BD01_0794	ENOG4105DQU	oxidoreductase, subunit beta
BD01_0798	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
BD01_0799	ENOG4105DQU	oxidoreductase, subunit beta
BD01_0806	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
BD01_0810	ENOG4108Z03	MAF-like protein
BD01_0812	ENOG4105CTP	PilT protein domain protein
BD01_0815	ENOG4105CAQ	asparagine synthetase
BD01_0817	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
BD01_0822	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
BD01_0823	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
BD01_0824	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
BD01_0827	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
BD01_0829	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
BD01_0831	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
BD01_0833	ENOG4105E8V	Alpha Beta Hydrolase Fold protein
BD01_0838	ENOG4105D0U	Arsenite-activated ATPase (ArsA)
BD01_0840	ENOG4105D22	carbon starvation protein
BD01_0841	ENOG4107QSA	Oxaloacetate decarboxylase
BD01_0842	ENOG41061GT	Aldolase
BD01_0850	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
BD01_0860	ENOG4105CD5	CoA-binding domain protein
BD01_0865	ENOG4105D1F	ATP-binding protein
BD01_0873	ENOG4108HWH	(ABC) transporter
BD01_0874	ENOG4105EHG	Permease protein
BD01_0875	ENOG4105S10	periplasmic binding protein
BD01_0877	ENOG4105C26	Dehydrogenase
BD01_0878	ENOG4108R96	Methyltransferase, YaeB family
BD01_0884	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
BD01_0887	ENOG4105VYW	UPF0251 protein
BD01_0890	ENOG4105C83	adenylosuccinate lyase
BD01_0893	ENOG4105C2X	Arabinose 5-phosphate isomerase
BD01_0895	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
BD01_0902	ENOG4107QRT	dEAD DEAH box helicase
BD01_0904	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
BD01_0905	ENOG4107VMB	Beta-lactamase domain protein
BD01_0908	ENOG4105F8V	Hydrolase, tatD family
BD01_0911	ENOG4105DCG	PHP domain protein
BD01_0912	ENOG4105D5P	Methylmalonyl-coA mutase
BD01_0916	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
BD01_0924	ENOG4105C1J	atp-dependent rna helicase
BD01_0929	ENOG4105C1J	atp-dependent rna helicase
BD01_0932	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
BD01_0934	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
BD01_0935	ENOG4105DCI	Phosphohydrolase
BD01_0936	ENOG4105CIG	ABC transporter
BD01_0945	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
BD01_0949	ENOG41065SU	Two-component system sensor kinase
BD01_0953	ENOG4105DIK	(ABC) transporter
BD01_0955	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
BD01_0959	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
BD01_0961	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
BD01_0965	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
BD01_0972	ENOG4108RCS	geranylgeranylglyceryl phosphate synthase
BD01_0977	ENOG4105WE2	aldehyde ferredoxin oxidoreductase
BD01_0991	ENOG4108JJB	ABC transporter
BD01_0993	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
BD01_0998	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
BD01_1002	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
BD01_1007	ENOG4105CJ1	ABC, transporter
BD01_1008	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
BD01_1010	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
BD01_1013	ENOG4107QMS	site-determining protein
BD01_1014	ENOG4107QX8	SPFH domain, Band 7 family protein
BD01_1021	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
BD01_1023	ENOG4105E7W	lamb ycsf family protein
BD01_1024	ENOG4105P4J	Allophanate hydrolase, subunit 1
BD01_1029	ENOG4107QW4	alcohol dehydrogenase
BD01_1032	ENOG4105ECY	inositol monophosphatase
BD01_1037	ENOG4105DVT	helicase
BD01_1040	ENOG4105CN9	Peptidase m42 family protein
BD01_1042	ENOG4105PW4	Sugar fermentation stimulation protein homolog
BD01_1044	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
BD01_1049	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
BD01_1051	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
BD01_1053	ENOG4105C6T	cysteine synthase
BD01_1055	ENOG4105CD5	CoA-binding domain protein
BD01_1062	ENOG4105CSM	endonuclease III
BD01_1068	ENOG4105BZA	Phosphoglycerate kinase
BD01_1077	ENOG4107Y70	Heat shock protein
BD01_1078	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
BD01_1091	ENOG4105DEF	Extracellular solute-binding protein, family 5
BD01_1092	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
BD01_1093	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
BD01_1095	ENOG4108JQ7	(ABC) transporter
BD01_1098	ENOG4107SA6	carbon-phosphorus lyase complex accessory protein
BD01_1103	ENOG4108TVJ	Nitroreductase
BD01_1131	ENOG4108Y5D	Inherit from COG: cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
BD01_1132	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
BD01_1138	ENOG4105EAC	phosphoserine phosphatase
BD01_1139	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
BD01_1154	ENOG4107T2S	C-20 methyltransferase BchU
BD01_1157	ENOG4108V3W	Chemotaxis protein, CheW
BD01_1158	ENOG4105C8Q	Methyl-accepting chemotaxis
BD01_1159	ENOG4105BZU	Histidine kinase
BD01_1160	ENOG4107YTP	response regulator receiver protein
BD01_1161	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
BD01_1162	ENOG4105CBS	Chea signal transduction histidine kinase
BD01_1165	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
BD01_1166	ENOG4105C8Q	Methyl-accepting chemotaxis
BD01_1166	ENOG4105C8Q	Methyl-accepting chemotaxis
BD01_1167	ENOG4105VAW	lrga family
BD01_1168	ENOG41067MG	lrgb family
BD01_1184	ENOG4107XZC	Restriction modification system DNA (Specificity
BD01_1199	ENOG4105VXP	Protein of unknown function DUF86
BD01_1200	ENOG4107S5Z	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity)
BD01_1203	ENOG4105CWC	Acetylornithine deacetylase
BD01_1208	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
BD01_1209	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
BD01_1214	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
BD01_1222	ENOG4108R9M	Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity)
BD01_1223	ENOG4105CXT	aspartate transcarbamylase
BD01_1224	ENOG4107ZCS	Phosphomethylpyrimidine kinase
BD01_1229	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
BD01_1232	ENOG4105NBF	ammecr1 domain protein
BD01_1236	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
BD01_1237	ENOG4105EHG	Permease protein
BD01_1238	ENOG4108Z24	l-2,4-diaminobutyric acid acetyltransferase
BD01_1242	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
BD01_1244	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
BD01_1249	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
BD01_1254	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
BD01_1255	ENOG4105E8R	UPF0173 metal-dependent hydrolase
BD01_1258	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
BD01_1266	ENOG4105DK7	lysyl-tRNA synthetase
BD01_1271	ENOG4107QNK	)-transporter
BD01_1273	ENOG4105D44	asparaginase
BD01_1275	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
BD01_1278	ENOG4105DJB	Major Facilitator Superfamily
BD01_1279	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
BD01_1281	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
BD01_1282	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
BD01_1284	ENOG4108UK2	deaminase
BD01_1285	ENOG4105D0M	Protease HtpX homolog
BD01_1292	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
BD01_1296	ENOG4105CJ1	ABC, transporter
BD01_1305	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
BD01_1308	ENOG4105CJ1	ABC, transporter
BD01_1311	ENOG4108IYU	L-aspartate oxidase
BD01_1314	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
BD01_1315	ENOG4105E4P	ATPase (AAA
BD01_1316	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
BD01_1323	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
BD01_1325	ENOG4105C0H	protease
BD01_1326	ENOG4105CG5	Glycosyl transferase (Group 1
BD01_1328	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
BD01_1330	ENOG4105CGN	Glycosyl transferase (Group 1
BD01_1331	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
BD01_1333	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
BD01_1336	ENOG4105FJR	Lmbe family
BD01_1339	ENOG4105CS2	ec 3.2.1.21
BD01_1343	ENOG4105C3U	ABC transporter
BD01_1344	ENOG4108JQ7	(ABC) transporter
BD01_1345	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
BD01_1347	ENOG41076HS	cation diffusion facilitator family transporter
BD01_1349	ENOG4107RWR	Sodium hydrogen exchanger
BD01_1353	ENOG4105C6W	4-alpha-glucanotransferase (EC 2.4.1.25)
BD01_1355	ENOG4107R56	PP-loop domain protein
BD01_1358	ENOG4105DZ0	fad dependent oxidoreductase
BD01_1359	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
BD01_1360	ENOG4107RWR	Sodium hydrogen exchanger
BD01_1365	ENOG4105C8Q	Methyl-accepting chemotaxis
BD01_1367	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
BD01_1376	ENOG4105VFR	signal peptidase
BD01_1378	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
BD01_1382	ENOG4107XF7	NGG1p interacting factor 3 protein, NIF3
BD01_1388	ENOG4105EHU	Circadian clock protein KaiC
BD01_1390	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
BD01_1392	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
BD01_1393	ENOG4105C1A	potassium transporter peripheral membrane
BD01_1397	ENOG4105K4G	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
BD01_1400	ENOG4108JIQ	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit (By similarity)
BD01_1404	ENOG4105EC8	Methyl-accepting chemotaxis
BD01_1405	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
BD01_1410	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
BD01_1415	ENOG4105DF0	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity)
BD01_1416	ENOG4105CD3	dihydroorotase
BD01_1419	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
BD01_1420	ENOG4105C3U	ABC transporter
BD01_1421	ENOG4108JQ7	(ABC) transporter
BD01_1423	ENOG4105C4K	Nad synthetase
BD01_1425	ENOG4105C5F	glutamine synthetase
BD01_1432	ENOG4105EHU	Circadian clock protein KaiC
BD01_1436	ENOG4105DR4	Methyltransferase
BD01_1437	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
BD01_1438	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
BD01_1439	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
BD01_1440	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
BD01_1442	ENOG4108NGU	Transcriptional regulator
BD01_1443	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
BD01_1445	ENOG4107QSQ	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
BD01_1450	ENOG4105M0J	Toxic component of a toxin-antitoxin (TA) module. A
BD01_1452	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
BD01_1453	ENOG4108K16	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
BD01_1455	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
BD01_1459	ENOG4108594	Permease of the drug metabolite transporter
BD01_1464	ENOG4105E4P	ATPase (AAA
BD01_1465	ENOG41081HM	2'-5' rna ligase
BD01_1469	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
BD01_1478	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
BD01_1481	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
BD01_1482	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
BD01_1484	ENOG4107V9E	glucose-1-phosphate thymidylyltransferase
BD01_1486	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
BD01_1487	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
BD01_1491	ENOG4108TJN	glycosyl transferase group 1
BD01_1493	ENOG4105CKK	Glycosyl transferase, family 2
BD01_1504	ENOG4105F0N	pyrophosphate phospho-hydrolase
BD01_1511	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
BD01_1525	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
BD01_1528	ENOG4107R7Y	intracellular protease Pfpi family
BD01_1530	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BD01_1533	ENOG4105CK7	Sodium proline symporter
BD01_1536	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
BD01_1539	ENOG4108IFG	nitrite reductase, (NAD(P)H)
BD01_1544	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
BD01_1551	ENOG4105K6H	D-cysteine desulfhydrase
BD01_1552	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
BD01_1555	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
BD01_1559	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
BD01_1561	ENOG4105FB2	class II Aldolase
BD01_1564	ENOG4108VVK	transcriptional Regulator, AsnC
BD01_1565	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
BD01_1568	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
BD01_1579	ENOG4107S6Z	Na H antiporter
BD01_1580	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
BD01_1582	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
BD01_1584	ENOG4105C8Q	Methyl-accepting chemotaxis
BD01_1594	ENOG4106IPI	cyclase, family
BD01_1595	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
BD01_1600	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
BD01_1601	ENOG4108R96	Methyltransferase, YaeB family
BD01_1602	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
BD01_1603	ENOG4105E0C	molybdate abc transporter
BD01_1604	ENOG41066FR	extracellular solute-binding protein
BD01_1607	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
BD01_1614	ENOG4105CHM	Aminotransferase
BD01_1617	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
BD01_1618	ENOG4107QJE	Chromosome Partitioning Protein
BD01_1620	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
BD01_1622	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
BD01_1626	ENOG4108Y5D	Inherit from COG: cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
BD01_1631	ENOG4105CJ1	ABC, transporter
BD01_1640	ENOG4105DT1	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate
BD01_1641	ENOG4107104	thymidine kinase
BD01_1642	ENOG4108IYI	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
BD01_1646	ENOG4108RMN	UPF0128 protein
BD01_1647	ENOG4106J7S	Glycosyl transferase, family 2
BD01_1650	ENOG4105D1Z	hydroxypyruvate reductase
BD01_1659	ENOG4105K4P	CoA-binding domain protein
BD01_1666	ENOG4105VZ8	Transcriptional regulator
BD01_1667	ENOG4105CJ1	ABC, transporter
BD01_1674	ENOG4105DUN	Mediates zinc uptake. May also transport other divalent cations (By similarity)
BD01_1682	ENOG4105CDJ	oxidoreductase FAD NAD(P)-binding domain protein
BD01_1683	ENOG4105BZ8	glutamate synthase
BD01_1686	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
BD01_1687	ENOG4105SC1	monovalent cation H antiporter subunit E
BD01_1688	ENOG41080TA	Multiple resistance and ph regulation protein f
BD01_1689	ENOG4105KJM	monovalent cation h antiporter subunit g
BD01_1694	ENOG4108JPZ	Monovalent cation H antiporter subunit D
BD01_1700	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
BD01_1706	ENOG4107WCI	zn-dependent hydrolase of the beta-lactamase fold-like protein
BD01_1707	ENOG4107QN1	sodium solute
BD01_1721	ENOG4105FBQ	ATPase associated with various cellular activities aaa_5
BD01_1729	ENOG4105CHU	acetyl-coa acetyltransferase
BD01_1730	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
BD01_1733	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
BD01_1734	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
BD01_1735	ENOG4108Z86	Glutamine amidotransferase
BD01_1737	ENOG4108UKZ	OsmC family
BD01_1738	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
BD01_1741	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
BD01_1743	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
BD01_1744	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
BD01_1748	ENOG4107QNG	Phosphoribosylglycinamide synthetase
BD01_1751	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
BD01_1752	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
BD01_1753	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
BD01_1756	ENOG4105C8V	SAICAR synthetase
BD01_1760	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
BD01_1761	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
BD01_1762	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
BD01_1766	ENOG4108KN7	Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity)
BD01_1771	ENOG4105CTD	carboxy-peptidase
BD01_1777	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
BD01_1782	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
BD01_1789	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
BD01_1790	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
BD01_1792	ENOG4105ERH	Fumarylacetoacetate hydrolase
BD01_1794	ENOG4105C31	Tryptophanyl-tRNA synthetase
BD01_1799	ENOG4107YM4	Beta-lactamase domain-containing protein
BD01_1801	ENOG41082SX	arsR family transcriptional regulator
BD01_1805	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
BD01_1808	ENOG4105D1H	recombination factor protein RarA
BD01_1810	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
BD01_1812	ENOG4105CB1	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
BD01_1816	ENOG4105CYV	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures (By similarity)
BD01_1822	ENOG4105EYW	Ion transport protein
BD01_1840	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
BD01_1842	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
BD01_1844	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
BD01_1854	ENOG4105D06	uba thif-type nad fad binding protein
BD01_1856	ENOG4108ZAF	Molybdopterin
BD01_1860	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
BD01_1861	ENOG4108VVK	transcriptional Regulator, AsnC
BD01_1864	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
BD01_1866	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
BD01_1869	ENOG4108JPW	Aminotransferase
BD01_1872	ENOG4105C3M	thioredoxin reductase
BD01_1881	ENOG4107TDF	Formate hydrogenlyase subunit 4
BD01_1882	ENOG4108HM5	NADH-ubiquinone oxidoreductase chain 49kDa
BD01_1883	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
BD01_1884	ENOG4105C47	NADH ubiquinone oxidoreductase 20 kda subunit
BD01_1886	ENOG4108JPZ	Monovalent cation H antiporter subunit D
BD01_1887	ENOG4105MKQ	Monovalent cation H antiporter subunit C
BD01_1891	ENOG4105KJM	monovalent cation h antiporter subunit g
BD01_1894	ENOG4105QAX	Iron-sulfur
BD01_1895	ENOG4105BZ8	glutamate synthase
BD01_1896	ENOG4105TMB	Formate nitrite transporter
BD01_1898	ENOG4105QAX	Iron-sulfur
BD01_1899	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
BD01_1903	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
BD01_1904	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
BD01_1909	ENOG4105CJ3	phosphate transporter
BD01_1914	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
BD01_1916	ENOG4105EHU	Circadian clock protein KaiC
BD01_1921	ENOG4105VFR	signal peptidase
BD01_1923	ENOG4107GFK	fumarate
BD01_1925	ENOG4105E4P	ATPase (AAA
BD01_1926	ENOG4108JQ1	Dehydrogenase
BD01_1930	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
BD01_1934	ENOG4107RWR	Sodium hydrogen exchanger
BD01_1939	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
BD01_1940	ENOG4105CJ3	phosphate transporter
BD01_1943	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
BD01_1944	ENOG4105DDK	oxidoreductase, beta subunit
BD01_1946	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
BD01_1947	ENOG4105DDK	oxidoreductase, beta subunit
BD01_1948	ENOG4105D1F	ATP-binding protein
BD01_1953	ENOG4108RVA	ribokinase
BD01_1955	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
BD01_1957	ENOG4108UUC	Protein of unknown function DUF99
BD01_1958	ENOG4107YZX	Universal stress protein
BD01_1959	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
BD01_1963	ENOG4107NFR	Fructose-1,6-bisphosphatase
BD01_1965	ENOG4105C1Q	protoporphyrinogen oxidase
BD01_1975	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
BD01_1979	ENOG4105CDJ	oxidoreductase FAD NAD(P)-binding domain protein
BD01_1980	ENOG4105BZ8	glutamate synthase
BD01_1984	ENOG4105CHR	reductase
BD01_1988	ENOG41084T3	4fe-4S ferredoxin iron-sulfur binding domain-containing protein
BD01_1989	ENOG4105VG1	fes assembly suf system protein
BD01_1992	ENOG4108JVH	Protein of unknown function DUF43
BD01_1994	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
BD01_1995	ENOG4105WE2	aldehyde ferredoxin oxidoreductase
BD01_1996	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
BD01_2003	ENOG4105IIU	Aminopeptidase
BD01_2017	ENOG4105K8R	UPF0145 protein
BD01_2021	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
BD01_2025	ENOG4105D64	Mechanosensitive ion channel
BD01_2033	ENOG4105EM7	Selenocysteine-specific translation elongation factor
BD01_2037	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
BD01_2038	ENOG410825M	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
BD01_2055	ENOG4105C5R	Aminotransferase
BD01_2058	ENOG4105C5S	asparaginyl-tRNA synthetase
BD01_2059	ENOG4107RGW	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BD01_2063	ENOG4107QIZ	NADH dehydrogenase
BD01_2066	ENOG4105DF0	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity)
BD01_2074	ENOG4105CKX	Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP
BD01_2081	ENOG4105D8K	carboxyl transferase
BD01_2083	ENOG4107QSA	Oxaloacetate decarboxylase
BD01_2084	ENOG4105D9Q	decarboxylase (Beta subunit)
BD01_2085	ENOG4105CJW	magnesium transporter
BD01_2086	ENOG4105D6E	homoserine dehydrogenase
BD01_2094	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
BD01_2095	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
BD01_2096	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
BD01_2111	ENOG4108RWI	nicotinamidase
BD01_2113	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
BD01_2114	ENOG4108NGU	Transcriptional regulator
BD01_2115	ENOG4105CJ1	ABC, transporter
BD01_2116	ENOG4107QWP	ABC-2 type transporter
BD01_2117	ENOG4105VUN	Transcriptional regulator
BD01_2119	ENOG4105HDK	L-asparaginase
BD01_2123	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
BD01_2125	ENOG4105DP8	Major facilitator superfamily MFS_1
BD01_2133	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
BD01_2134	ENOG4105NBF	ammecr1 domain protein
BD01_2142	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
BD01_2143	ENOG4105C7N	Xanthine uracil vitamin C permease
BD01_2148	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
BD01_2150	ENOG41080UE	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
BD01_2151	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BD01_2152	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
BD01_2154	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
BD01_2155	ENOG41082SA	50s ribosomal protein l29
BD01_2156	ENOG4108ZJT	translation initiation factor, Sui1
BD01_2158	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
BD01_2159	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
BD01_2160	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
BD01_2162	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BD01_2164	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
BD01_2165	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
BD01_2168	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
BD01_2169	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
BD01_2170	ENOG4105VPB	50S ribosomal protein L30
BD01_2171	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
BD01_2176	ENOG4108Z4J	Cytidine monophosphate kinase
BD01_2180	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
BD01_2183	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
BD01_2185	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BD01_2186	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
BD01_2187	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
BD01_2191	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
BD01_2192	ENOG4108UJD	30S ribosomal protein S9
BD01_2196	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
BD01_2197	ENOG4105CE9	30S ribosomal protein S2
BD01_2200	ENOG4105K7K	Transcriptional regulator
BD01_2206	ENOG4108YXU	transcriptional regulator AsnC family
BD01_2208	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
BD01_2211	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BD01_2216	ENOG4105CB1	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
BD01_2222	ENOG4108I5U	Uridine phosphorylase
BD01_2224	ENOG41074MP	UPF0103 Mediator of ErbB2-driven cell motility-containing protein
BD01_2226	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
BD01_2229	ENOG4106UJV	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
BD01_2236	ENOG4105C8T	Leucyl-tRNA synthetase
BD01_2241	ENOG4105CIG	ABC transporter
BD01_2251	ENOG4108JEB	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
BD01_2256	ENOG4105MRR	Transcriptional regulator (By similarity)
BD01_2259	ENOG4107RFW	hydrolase family 57
BD01_2262	ENOG4105C8J	)-transporter
BD01_2263	ENOG4105D82	Glutamate dehydrogenase
BD01_2265	ENOG4105KPK	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation (By similarity)
BD01_2266	ENOG4105CY0	Metallo-Beta-Lactamase
BD01_2268	ENOG4105E66	phosphoriboisomerase A