locus-tag	class	description
BD01_0023	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BD01_0027	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
BD01_0029	COG0058	SHG alpha-glucan phosphorylase activity
BD01_0031	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BD01_0039	COG0717	Belongs to the dCTP deaminase family
BD01_0044	COG0081	regulation of translation
BD01_0045	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BD01_0048	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BD01_0058	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BD01_0059	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BD01_0064	COG2339	peptidase activity
BD01_0070	COG0579	oxidoreductase
BD01_0076	COG0584	glycerophosphoryl diester phosphodiesterase
BD01_0077	COG0584	glycerophosphoryl diester phosphodiesterase
BD01_0078	COG2211	Major facilitator Superfamily
BD01_0081	COG2361	Protein of unknown function DUF86
BD01_0082	COG0429	hydrolase of the alpha beta-hydrolase fold
BD01_0085	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BD01_0086	COG0534	Mate efflux family protein
BD01_0087	COG0534	Mate efflux family protein
BD01_0090	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BD01_0090	COG0574	Belongs to the PEP-utilizing enzyme family
BD01_0095	COG1404	Belongs to the peptidase S8 family
BD01_0095	COG1404	Belongs to the peptidase S8 family
BD01_0098	COG0446	pyridine nucleotide-disulphide oxidoreductase
BD01_0102	COG0731	radical SAM domain protein
BD01_0102	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BD01_0107	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BD01_0110	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BD01_0111	COG0309	Hydrogenase expression formation protein (HypE)
BD01_0114	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
BD01_0115	COG0409	Hydrogenase expression formation protein
BD01_0116	COG0298	carbon dioxide binding
BD01_0119	COG1309	transcriptional regulator
BD01_0120	COG3383	formate dehydrogenase (NAD+) activity
BD01_0121	COG0437	4 iron, 4 sulfur cluster binding
BD01_0122	COG2111	Na H antiporter
BD01_0122	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BD01_0123	COG0651	ATP synthesis coupled electron transport
BD01_0124	COG0650	Formate hydrogenlyase subunit 4
BD01_0125	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
BD01_0125	COG3261	NADH dehydrogenase
BD01_0126	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BD01_0127	COG3260	NADH ubiquinone oxidoreductase 20
BD01_0130	COG0746	molybdenum cofactor guanylyltransferase activity
BD01_0136	COG0489	protein tyrosine kinase activity
BD01_0145	COG1120	ATPase activity
BD01_0147	COG1234	tRNA 3'-trailer cleavage
BD01_0150	COG2140	Oxalate decarboxylase
BD01_0153	COG0561	phosphatase activity
BD01_0165	COG1122	ATPase activity
BD01_0166	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BD01_0168	COG0310	cobalt ion transport
BD01_0171	COG1185	polyribonucleotide nucleotidyltransferase activity
BD01_0177	COG0436	Aminotransferase
BD01_0180	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BD01_0185	COG3634	alkyl hydroperoxide reductase activity
BD01_0187	COG0085	RNA polymerase activity
BD01_0188	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BD01_0189	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BD01_0193	COG0049	tRNA binding
BD01_0208	COG1203	CRISPR-associated helicase, Cas3
BD01_0210	COG1518	maintenance of DNA repeat elements
BD01_0211	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
BD01_0217	COG1110	DNA topoisomerase II activity
BD01_0224	COG0546	phosphoglycolate phosphatase activity
BD01_0232	COG1418	mRNA catabolic process
BD01_0234	COG0017	Asparaginyl-tRNA synthetase
BD01_0237	COG0585	pseudouridine synthase activity
BD01_0241	COG1473	amidohydrolase
BD01_0251	COG0359	binds to the 23S rRNA
BD01_0251	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
BD01_0254	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BD01_0254	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BD01_0257	COG0656	L-ascorbic acid biosynthetic process
BD01_0264	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
BD01_0267	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BD01_0269	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
BD01_0270	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BD01_0279	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BD01_0281	COG0010	Belongs to the arginase family
BD01_0282	COG0025	NhaP-type Na H and K H
BD01_0286	COG2002	toxin-antitoxin pair type II binding
BD01_0287	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BD01_0295	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BD01_0297	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BD01_0304	COG0252	asparaginase activity
BD01_0305	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BD01_0309	COG2894	cell division
BD01_0310	COG1063	alcohol dehydrogenase
BD01_0311	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BD01_0315	COG0101	tRNA pseudouridine synthase activity
BD01_0316	COG0556	nucleotide-excision repair
BD01_0319	COG1131	(ABC) transporter
BD01_0325	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BD01_0326	COG0628	permease
BD01_0328	COG0616	signal peptide processing
BD01_0334	COG1185	polyribonucleotide nucleotidyltransferase activity
BD01_0335	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BD01_0338	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BD01_0346	COG1122	ATPase activity
BD01_0347	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BD01_0348	COG0024	Methionine aminopeptidase
BD01_0350	COG0517	IMP dehydrogenase activity
BD01_0350	COG0516	GMP reductase activity
BD01_0354	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BD01_0355	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BD01_0360	COG0504	CTP synthase activity
BD01_0369	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BD01_0373	COG1881	PFAM PEBP family protein
BD01_0382	COG1151	hydroxylamine reductase activity
BD01_0389	COG0649	NAD binding
BD01_0391	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BD01_0393	COG0651	ATP synthesis coupled electron transport
BD01_0394	COG0651	ATP synthesis coupled electron transport
BD01_0395	COG1006	Multisubunit Na H antiporter MnhC subunit
BD01_0396	COG2111	Na H antiporter
BD01_0396	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BD01_0398	COG1320	monovalent cation:proton antiporter activity
BD01_0399	COG2212	antiporter activity
BD01_0400	COG1863	multisubunit Na H antiporter MnhE subunit
BD01_0402	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BD01_0406	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BD01_0410	COG0018	arginyl-trna synthetase
BD01_0423	COG1363	Peptidase, m42
BD01_0438	COG1941	NADH ubiquinone oxidoreductase 20 kDa subunit
BD01_0443	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BD01_0444	COG1476	TRANSCRIPTIONal
BD01_0447	COG0569	domain protein
BD01_0451	COG1515	deoxyribonuclease V activity
BD01_0453	COG1812	S-adenosylmethionine synthetase (AdoMet synthetase)
BD01_0455	COG0420	3'-5' exonuclease activity
BD01_0457	COG0436	Aminotransferase
BD01_0461	COG0546	phosphoglycolate phosphatase activity
BD01_0462	COG0719	Fe-S assembly protein
BD01_0463	COG0396	ATPase activity
BD01_0469	COG1694	Mazg nucleotide pyrophosphohydrolase
BD01_0470	COG1522	sequence-specific DNA binding
BD01_0471	COG1836	PFAM Integral membrane protein DUF92
BD01_0472	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BD01_0472	COG0301	tRNA thio-modification
BD01_0477	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BD01_0495	COG2814	Major facilitator Superfamily
BD01_0499	COG2096	Adenosyltransferase
BD01_0501	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
BD01_0503	COG1505	serine-type exopeptidase activity
BD01_0504	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BD01_0504	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BD01_0505	COG0307	riboflavin synthase, alpha
BD01_0506	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BD01_0506	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BD01_0511	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BD01_0513	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
BD01_0514	COG0352	thiamine-phosphate diphosphorylase activity
BD01_0514	COG0351	phosphomethylpyrimidine kinase
BD01_0515	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BD01_0518	COG1047	Peptidyl-prolyl cis-trans
BD01_0519	COG0215	cysteine-tRNA ligase activity
BD01_0530	COG0730	response to heat
BD01_0532	COG0730	response to heat
BD01_0534	COG2002	toxin-antitoxin pair type II binding
BD01_0536	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BD01_0537	COG0442	prolyl-tRNA aminoacylation
BD01_0539	COG2192	nodulation
BD01_0540	COG1794	racemase activity, acting on amino acids and derivatives
BD01_0541	COG0668	transmembrane transport
BD01_0544	COG1993	acr, cog1993
BD01_0545	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BD01_0551	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BD01_0554	COG0163	prenyltransferase activity
BD01_0555	COG1522	sequence-specific DNA binding
BD01_0557	COG0012	GTP binding
BD01_0558	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BD01_0561	COG0312	modulator of DNA gyrase
BD01_0569	COG0525	valine-tRNA ligase activity
BD01_0571	COG2226	methyltransferase
BD01_0572	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BD01_0573	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
BD01_0584	COG1492	cobalamin metabolic process
BD01_0585	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
BD01_0589	COG0521	Mo-molybdopterin cofactor biosynthetic process
BD01_0592	COG0303	'Molybdopterin
BD01_0598	COG1078	dGTPase activity
BD01_0601	COG0450	alkyl hydroperoxide reductase
BD01_0602	COG0243	molybdopterin cofactor binding
BD01_0609	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BD01_0614	COG0105	UTP biosynthetic process
BD01_0620	COG0175	sulfate reduction
BD01_0633	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BD01_0635	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BD01_0641	COG0419	ATPase involved in DNA repair
BD01_0641	COG0419	ATPase involved in DNA repair
BD01_0645	COG0840	transmembrane signaling receptor activity
BD01_0650	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BD01_0651	COG1028	Short-chain dehydrogenase reductase Sdr
BD01_0652	COG0493	'glutamate synthase
BD01_0653	COG1899	peptidyl-lysine modification to peptidyl-hypusine
BD01_0658	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BD01_0662	COG0778	Nitroreductase
BD01_0665	COG0651	ATP synthesis coupled electron transport
BD01_0666	COG1863	multisubunit Na H antiporter MnhE subunit
BD01_0667	COG1006	Multisubunit Na H antiporter MnhC subunit
BD01_0670	COG1320	monovalent cation:proton antiporter activity
BD01_0671	COG2212	antiporter activity
BD01_0673	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BD01_0674	COG1528	Iron-storage protein
BD01_0676	COG0426	domain, Protein
BD01_0677	COG1592	Rubrerythrin
BD01_0678	COG1773	rubredoxin
BD01_0679	COG2033	superoxide reductase activity
BD01_0692	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BD01_0695	COG3842	ATPase activity
BD01_0696	COG4149	molybdate abc transporter
BD01_0700	COG1522	sequence-specific DNA binding
BD01_0706	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BD01_0707	COG1122	ATPase activity
BD01_0708	COG1268	BioY protein
BD01_0713	COG0823	Involved in the tonB-independent uptake of proteins
BD01_0713	COG1506	peptidase
BD01_0713	COG4946	Tricorn protease homolog
BD01_0714	COG1444	tRNA N-acetyltransferase activity
BD01_0717	COG4143	(ABC) transporter
BD01_0722	COG2815	serine threonine protein kinase
BD01_0722	COG0515	serine threonine protein kinase
BD01_0724	COG0515	serine threonine protein kinase
BD01_0724	COG2815	serine threonine protein kinase
BD01_0726	COG2815	serine threonine protein kinase
BD01_0726	COG0515	serine threonine protein kinase
BD01_0728	COG0402	S-adenosylhomocysteine deaminase activity
BD01_0729	COG0017	Asparaginyl-tRNA synthetase
BD01_0734	COG0306	phosphate transporter
BD01_0737	COG1201	RNA secondary structure unwinding
BD01_0738	COG0006	proline dipeptidase activity
BD01_0741	COG1867	N(2),N(2)-dimethylguanosine tRNA methyltransferase
BD01_0745	COG0534	Mate efflux family protein
BD01_0748	COG0423	glycine-tRNA ligase activity
BD01_0749	COG2361	Protein of unknown function DUF86
BD01_0754	COG1872	DUF167
BD01_0757	COG1546	Belongs to the CinA family
BD01_0757	COG1058	Belongs to the CinA family
BD01_0762	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BD01_0765	COG1918	ferrous iron import across plasma membrane
BD01_0765	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BD01_0781	COG0457	Tetratricopeptide repeat
BD01_0781	COG0552	protein localization to endoplasmic reticulum
BD01_0786	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
BD01_0793	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BD01_0793	COG0674	pyruvate-flavodoxin oxidoreductase activity
BD01_0794	COG1013	pyruvate-flavodoxin oxidoreductase activity
BD01_0798	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BD01_0798	COG0674	pyruvate-flavodoxin oxidoreductase activity
BD01_0799	COG1013	pyruvate-flavodoxin oxidoreductase activity
BD01_0806	COG0720	synthase
BD01_0810	COG0424	maF-like protein
BD01_0812	COG4956	integral membrane protein (PIN domain superfamily)
BD01_0813	COG2894	cell division
BD01_0815	COG0367	asparagine synthase
BD01_0817	COG0009	L-threonylcarbamoyladenylate synthase
BD01_0822	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BD01_0823	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BD01_0824	COG0303	'Molybdopterin
BD01_0827	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BD01_0829	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BD01_0831	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BD01_0833	COG2267	carboxylic ester hydrolase activity
BD01_0838	COG0003	Pfam Anion-transporting ATPase
BD01_0840	COG1966	Carbon starvation protein
BD01_0841	COG5016	pyruvate
BD01_0841	COG0511	ligase activity, forming carbon-carbon bonds
BD01_0842	COG1830	Aldolase
BD01_0850	COG0482	sulfurtransferase activity
BD01_0860	COG1042	CoA-binding domain protein
BD01_0860	COG0045	succinate-CoA ligase (ADP-forming) activity
BD01_0860	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BD01_0865	COG0489	protein tyrosine kinase activity
BD01_0866	COG0489	protein tyrosine kinase activity
BD01_0873	COG1120	ATPase activity
BD01_0877	COG1012	belongs to the aldehyde dehydrogenase family
BD01_0884	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BD01_0887	COG1342	Belongs to the UPF0251 family
BD01_0890	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BD01_0893	COG0517	IMP dehydrogenase activity
BD01_0893	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BD01_0895	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
BD01_0899	COG2814	Major facilitator Superfamily
BD01_0902	COG1201	RNA secondary structure unwinding
BD01_0904	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BD01_0905	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BD01_0908	COG0084	hydrolase, TatD family'
BD01_0911	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BD01_0912	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BD01_0912	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BD01_0916	COG1196	nuclear chromosome segregation
BD01_0924	COG0513	Belongs to the DEAD box helicase family
BD01_0929	COG0513	Belongs to the DEAD box helicase family
BD01_0932	COG0051	transcription antitermination factor activity, RNA binding
BD01_0934	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BD01_0935	COG1078	dGTPase activity
BD01_0945	COG1469	GTP cyclohydrolase I activity
BD01_0949	COG2205	protein histidine kinase activity
BD01_0953	COG1121	(ABC) transporter
BD01_0955	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BD01_0959	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BD01_0961	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BD01_0965	COG0563	adenylate kinase activity
BD01_0972	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
BD01_0977	COG2414	aldehyde ferredoxin oxidoreductase
BD01_0984	COG2403	cyclic 2,3-diphosphoglycerate synthetase activity
BD01_0991	COG1129	ABC transporter
BD01_0993	COG1739	Uncharacterized protein family UPF0029
BD01_0998	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BD01_1002	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BD01_1002	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
BD01_1007	COG1131	(ABC) transporter
BD01_1008	COG0315	cyclic pyranopterin monophosphate synthase activity
BD01_1010	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
BD01_1013	COG2894	cell division
BD01_1014	COG0330	HflC and HflK could
BD01_1017	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BD01_1021	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BD01_1023	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BD01_1024	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BD01_1027	COG1984	allophanate hydrolase subunit 2
BD01_1029	COG1979	alcohol dehydrogenase
BD01_1032	COG0483	inositol monophosphate 1-phosphatase activity
BD01_1037	COG1199	ATP-dependent helicase activity
BD01_1042	COG1489	DNA binding
BD01_1044	COG4974	Belongs to the 'phage' integrase family
BD01_1049	COG0301	tRNA thio-modification
BD01_1051	COG0301	tRNA thio-modification
BD01_1053	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BD01_1055	COG0045	succinate-CoA ligase (ADP-forming) activity
BD01_1055	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BD01_1055	COG1042	CoA-binding domain protein
BD01_1062	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BD01_1067	COG1695	Transcriptional regulator
BD01_1068	COG0126	phosphoglycerate kinase activity
BD01_1077	COG0071	Belongs to the small heat shock protein (HSP20) family
BD01_1078	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BD01_1091	COG0747	negative chemotaxis
BD01_1092	COG0601	transmembrane transport
BD01_1094	COG0444	Belongs to the ABC transporter superfamily
BD01_1095	COG4608	Belongs to the ABC transporter superfamily
BD01_1098	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BD01_1103	COG0778	Nitroreductase
BD01_1124	COG2814	Major facilitator Superfamily
BD01_1125	COG1051	belongs to the nudix hydrolase family
BD01_1125	COG1056	cytidyltransferase-related domain
BD01_1131	COG1213	nucleotidyl transferase
BD01_1131	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BD01_1132	COG0546	phosphoglycolate phosphatase activity
BD01_1138	COG0560	Phosphoserine phosphatase
BD01_1139	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BD01_1154	COG2813	Specifically methylates the guanine in position
BD01_1157	COG0835	chemotaxis
BD01_1158	COG0840	transmembrane signaling receptor activity
BD01_1160	COG2201	protein-glutamate methylesterase activity
BD01_1161	COG2201	protein-glutamate methylesterase activity
BD01_1162	COG2198	Histidine kinase
BD01_1162	COG0643	Histidine kinase
BD01_1165	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
BD01_1166	COG0840	transmembrane signaling receptor activity
BD01_1166	COG0840	transmembrane signaling receptor activity
BD01_1167	COG1380	Effector of murein hydrolase LrgA
BD01_1168	COG1346	cytolysis
BD01_1184	COG0732	type I restriction modification DNA specificity domain
BD01_1188	COG1451	nucleotide metabolic process
BD01_1199	COG2361	Protein of unknown function DUF86
BD01_1200	COG0095	Lipoate-protein ligase
BD01_1203	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BD01_1208	COG0312	modulator of DNA gyrase
BD01_1209	COG0312	modulator of DNA gyrase
BD01_1212	COG0434	BtpA family
BD01_1214	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BD01_1222	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
BD01_1223	COG0540	Belongs to the ATCase OTCase family
BD01_1224	COG0351	phosphomethylpyrimidine kinase
BD01_1224	COG1992	Thiamine-phosphate synthase
BD01_1229	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BD01_1232	COG2078	PFAM AMMECR1 domain protein
BD01_1232	COG3885	ferrous iron binding
BD01_1236	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
BD01_1237	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BD01_1238	COG0456	acetyltransferase
BD01_1242	COG0156	8-amino-7-oxononanoate synthase activity
BD01_1244	COG2255	four-way junction helicase activity
BD01_1249	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BD01_1254	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BD01_1255	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BD01_1266	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
BD01_1271	COG2814	Major facilitator Superfamily
BD01_1273	COG1446	asparaginase
BD01_1275	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BD01_1278	COG2271	Major facilitator Superfamily
BD01_1279	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BD01_1281	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BD01_1282	COG0546	phosphoglycolate phosphatase activity
BD01_1284	COG2131	deaminase
BD01_1285	COG0501	Belongs to the peptidase M48B family
BD01_1296	COG1131	(ABC) transporter
BD01_1305	COG0517	IMP dehydrogenase activity
BD01_1305	COG0516	GMP reductase activity
BD01_1308	COG1131	(ABC) transporter
BD01_1311	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BD01_1314	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BD01_1315	COG1373	ATPase (AAA superfamily
BD01_1316	COG0157	Belongs to the NadC ModD family
BD01_1323	COG0037	tRNA processing
BD01_1325	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BD01_1326	COG0438	transferase activity, transferring glycosyl groups
BD01_1328	COG0297	glycogen (starch) synthase activity
BD01_1330	COG0438	transferase activity, transferring glycosyl groups
BD01_1331	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BD01_1333	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BD01_1339	COG2723	6-phospho-beta-galactosidase activity
BD01_1343	COG0444	Belongs to the ABC transporter superfamily
BD01_1344	COG4608	Belongs to the ABC transporter superfamily
BD01_1345	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BD01_1347	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BD01_1349	COG0475	glutathione-regulated potassium exporter activity
BD01_1353	COG1449	Belongs to the glycosyl hydrolase 57 family
BD01_1355	COG0037	tRNA processing
BD01_1358	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
BD01_1359	COG0517	IMP dehydrogenase activity
BD01_1359	COG0516	GMP reductase activity
BD01_1360	COG0475	glutathione-regulated potassium exporter activity
BD01_1365	COG3290	protein histidine kinase activity
BD01_1365	COG0840	transmembrane signaling receptor activity
BD01_1367	COG2095	MarC family integral membrane protein
BD01_1376	COG0681	Belongs to the peptidase S26 family
BD01_1378	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BD01_1382	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BD01_1388	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
BD01_1390	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
BD01_1392	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BD01_1393	COG0569	domain protein
BD01_1395	COG1269	ATP hydrolysis coupled proton transport
BD01_1397	COG1390	Produces ATP from ADP in the presence of a proton gradient across the membrane
BD01_1400	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
BD01_1403	COG0426	domain, Protein
BD01_1403	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BD01_1404	COG5278	phosphoserine phosphatase activity
BD01_1404	COG0840	transmembrane signaling receptor activity
BD01_1405	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BD01_1415	COG0543	2 iron, 2 sulfur cluster binding
BD01_1416	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BD01_1418	COG0601	transmembrane transport
BD01_1419	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BD01_1420	COG0444	Belongs to the ABC transporter superfamily
BD01_1421	COG4608	Belongs to the ABC transporter superfamily
BD01_1425	COG0174	glutamine synthetase
BD01_1432	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
BD01_1436	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BD01_1438	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BD01_1439	COG1234	tRNA 3'-trailer cleavage
BD01_1440	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BD01_1442	COG1378	Sugar-specific transcriptional regulator TrmB
BD01_1443	COG0297	glycogen (starch) synthase activity
BD01_1445	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BD01_1450	COG1487	ribonuclease activity
BD01_1453	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
BD01_1455	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BD01_1464	COG1373	ATPase (AAA superfamily
BD01_1465	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BD01_1469	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BD01_1478	COG0714	Associated with various cellular activities
BD01_1481	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BD01_1482	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BD01_1487	COG1091	dTDP-4-dehydrorhamnose reductase activity
BD01_1488	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BD01_1493	COG0463	Glycosyl transferase, family 2
BD01_1504	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BD01_1510	COG1404	Belongs to the peptidase S8 family
BD01_1511	COG2890	protein-(glutamine-N5) methyltransferase activity
BD01_1525	COG2095	MarC family integral membrane protein
BD01_1528	COG0693	protein deglycase activity
BD01_1529	COG1522	sequence-specific DNA binding
BD01_1530	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BD01_1536	COG2814	Major facilitator Superfamily
BD01_1539	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BD01_1545	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BD01_1551	COG2515	1-aminocyclopropane-1-carboxylate deaminase
BD01_1552	COG0167	dihydroorotate dehydrogenase activity
BD01_1555	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BD01_1559	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
BD01_1561	COG0235	Class ii aldolase
BD01_1564	COG1522	sequence-specific DNA binding
BD01_1565	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BD01_1568	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BD01_1579	COG1757	Na H antiporter
BD01_1580	COG1573	uracil-dna glycosylase
BD01_1582	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BD01_1584	COG0840	transmembrane signaling receptor activity
BD01_1594	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
BD01_1595	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
BD01_1597	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
BD01_1600	COG0714	Associated with various cellular activities
BD01_1602	COG3842	ATPase activity
BD01_1603	COG4149	molybdate abc transporter
BD01_1604	COG0725	ABC transporter, periplasmic molybdate-binding protein
BD01_1607	COG1160	GTP binding
BD01_1613	COG2119	membrane
BD01_1617	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BD01_1618	COG1192	Involved in chromosome partitioning
BD01_1620	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BD01_1620	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
BD01_1622	COG0284	orotidine-5'-phosphate decarboxylase activity
BD01_1626	COG1213	nucleotidyl transferase
BD01_1626	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BD01_1631	COG1131	(ABC) transporter
BD01_1642	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BD01_1646	COG1851	Uncharacterised protein family (UPF0128)
BD01_1647	COG0463	Glycosyl transferase, family 2
BD01_1650	COG2379	hydroxypyruvate reductase
BD01_1659	COG1832	CoA-binding protein
BD01_1666	COG1476	TRANSCRIPTIONal
BD01_1667	COG1131	(ABC) transporter
BD01_1674	COG0428	transporter
BD01_1682	COG0543	2 iron, 2 sulfur cluster binding
BD01_1683	COG0493	'glutamate synthase
BD01_1683	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
BD01_1686	COG0509	glycine decarboxylation via glycine cleavage system
BD01_1687	COG1863	multisubunit Na H antiporter MnhE subunit
BD01_1688	COG2212	antiporter activity
BD01_1694	COG0651	ATP synthesis coupled electron transport
BD01_1700	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BD01_1706	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BD01_1707	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BD01_1714	COG0123	including yeast histone deacetylase and acetoin utilization protein
BD01_1721	COG1401	restriction endodeoxyribonuclease activity
BD01_1729	COG0183	Belongs to the thiolase family
BD01_1730	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BD01_1733	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
BD01_1734	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BD01_1735	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BD01_1737	COG1765	OsmC-like protein
BD01_1738	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BD01_1738	COG0519	Catalyzes the synthesis of GMP from XMP
BD01_1741	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BD01_1741	COG0519	Catalyzes the synthesis of GMP from XMP
BD01_1743	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BD01_1744	COG0047	phosphoribosylformylglycinamidine synthase activity
BD01_1748	COG0151	Belongs to the GarS family
BD01_1751	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BD01_1752	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
BD01_1753	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BD01_1756	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BD01_1757	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BD01_1760	COG3383	formate dehydrogenase (NAD+) activity
BD01_1761	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
BD01_1762	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
BD01_1770	COG2442	InterPro IPR007367
BD01_1771	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BD01_1777	COG0714	Associated with various cellular activities
BD01_1782	COG1047	Peptidyl-prolyl cis-trans
BD01_1789	COG1160	GTP binding
BD01_1790	COG0116	Belongs to the methyltransferase superfamily
BD01_1792	COG0179	Fumarylacetoacetate (FAA) hydrolase
BD01_1794	COG0180	Tryptophanyl-tRNA synthetase
BD01_1799	COG1234	tRNA 3'-trailer cleavage
BD01_1801	COG0640	Transcriptional regulator
BD01_1805	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BD01_1805	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BD01_1808	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
BD01_1808	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BD01_1810	COG0402	S-adenosylhomocysteine deaminase activity
BD01_1812	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BD01_1816	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
BD01_1822	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BD01_1840	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BD01_1842	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BD01_1844	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BD01_1844	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
BD01_1854	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BD01_1856	COG0314	molybdopterin synthase activity
BD01_1860	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BD01_1861	COG1522	sequence-specific DNA binding
BD01_1864	COG0148	phosphopyruvate hydratase activity
BD01_1866	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BD01_1869	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BD01_1872	COG0492	ferredoxin-NADP+ reductase activity
BD01_1881	COG0650	Formate hydrogenlyase subunit 4
BD01_1883	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
BD01_1883	COG3261	NADH dehydrogenase
BD01_1884	COG3260	NADH ubiquinone oxidoreductase 20
BD01_1886	COG0651	ATP synthesis coupled electron transport
BD01_1891	COG1320	monovalent cation:proton antiporter activity
BD01_1892	COG2212	antiporter activity
BD01_1894	COG0437	4 iron, 4 sulfur cluster binding
BD01_1895	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
BD01_1895	COG0493	'glutamate synthase
BD01_1896	COG2116	formate transmembrane transporter activity
BD01_1898	COG0437	4 iron, 4 sulfur cluster binding
BD01_1899	COG3383	formate dehydrogenase (NAD+) activity
BD01_1902	COG3259	Nickel-dependent hydrogenase
BD01_1903	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BD01_1904	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BD01_1909	COG0306	phosphate transporter
BD01_1914	COG0823	Involved in the tonB-independent uptake of proteins
BD01_1914	COG4946	Tricorn protease homolog
BD01_1914	COG1506	peptidase
BD01_1916	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
BD01_1921	COG0681	Belongs to the peptidase S26 family
BD01_1925	COG1373	ATPase (AAA superfamily
BD01_1926	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BD01_1930	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
BD01_1934	COG0475	glutathione-regulated potassium exporter activity
BD01_1939	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BD01_1940	COG0306	phosphate transporter
BD01_1943	COG0674	pyruvate-flavodoxin oxidoreductase activity
BD01_1944	COG1013	pyruvate-flavodoxin oxidoreductase activity
BD01_1946	COG0674	pyruvate-flavodoxin oxidoreductase activity
BD01_1947	COG1013	pyruvate-flavodoxin oxidoreductase activity
BD01_1948	COG0489	protein tyrosine kinase activity
BD01_1953	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BD01_1955	COG1254	Belongs to the acylphosphatase family
BD01_1957	COG1628	Protein of unknown function DUF99
BD01_1958	COG0589	response to stress
BD01_1959	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BD01_1963	COG1980	fructose-bisphosphate aldolase activity
BD01_1975	COG2226	methyltransferase
BD01_1979	COG0543	2 iron, 2 sulfur cluster binding
BD01_1980	COG0493	'glutamate synthase
BD01_1980	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
BD01_1984	COG1028	Short-chain dehydrogenase reductase Sdr
BD01_1988	COG1141	Ferredoxin
BD01_1989	COG2151	metal-sulfur cluster biosynthetic enzyme
BD01_1994	COG1404	Belongs to the peptidase S8 family
BD01_1995	COG2414	aldehyde ferredoxin oxidoreductase
BD01_1996	COG0535	radical SAM domain protein
BD01_2001	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
BD01_2003	COG2234	aminopeptidase activity
BD01_2017	COG0393	Putative heavy-metal-binding
BD01_2021	COG2264	protein methyltransferase activity
BD01_2025	COG0668	transmembrane transport
BD01_2030	COG1598	PFAM Uncharacterised protein family UPF0150
BD01_2038	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BD01_2040	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BD01_2055	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BD01_2058	COG0017	Asparaginyl-tRNA synthetase
BD01_2066	COG0543	2 iron, 2 sulfur cluster binding
BD01_2074	COG0430	RNA-3'-phosphate cyclase activity
BD01_2081	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BD01_2083	COG0511	ligase activity, forming carbon-carbon bonds
BD01_2083	COG5016	pyruvate
BD01_2084	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
BD01_2085	COG2239	Acts as a magnesium transporter
BD01_2086	COG0460	homoserine dehydrogenase
BD01_2094	COG1185	polyribonucleotide nucleotidyltransferase activity
BD01_2095	COG1185	polyribonucleotide nucleotidyltransferase activity
BD01_2098	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
BD01_2111	COG1335	isochorismatase
BD01_2113	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
BD01_2113	COG2050	protein possibly involved in aromatic compounds catabolism
BD01_2114	COG1378	Sugar-specific transcriptional regulator TrmB
BD01_2115	COG1131	(ABC) transporter
BD01_2116	COG0842	Transport permease protein
BD01_2117	COG1695	Transcriptional regulator
BD01_2119	COG0252	asparaginase activity
BD01_2123	COG1185	polyribonucleotide nucleotidyltransferase activity
BD01_2133	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BD01_2133	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BD01_2134	COG2078	PFAM AMMECR1 domain protein
BD01_2135	COG0011	TIGRFAM Protein of
BD01_2141	COG4208	sulfate ABC transporter
BD01_2142	COG3842	ATPase activity
BD01_2143	COG2252	PERMEase
BD01_2148	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BD01_2150	COG0089	rRNA binding
BD01_2151	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BD01_2152	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BD01_2154	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BD01_2155	COG0255	Belongs to the universal ribosomal protein uL29 family
BD01_2156	COG0023	Translation Initiation Factor
BD01_2158	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BD01_2159	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BD01_2160	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BD01_2162	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BD01_2164	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BD01_2165	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BD01_2168	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BD01_2169	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BD01_2170	COG1841	ribosomal large subunit assembly
BD01_2171	COG0200	Binds to the 23S rRNA
BD01_2176	COG1102	Psort location Cytoplasmic, score
BD01_2178	COG1598	PFAM Uncharacterised protein family UPF0150
BD01_2180	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BD01_2183	COG2813	Specifically methylates the guanine in position
BD01_2185	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BD01_2186	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BD01_2191	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BD01_2192	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BD01_2196	COG0148	phosphopyruvate hydratase activity
BD01_2197	COG0052	Belongs to the universal ribosomal protein uS2 family
BD01_2200	COG1695	Transcriptional regulator
BD01_2206	COG1522	sequence-specific DNA binding
BD01_2208	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BD01_2211	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BD01_2216	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BD01_2217	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BD01_2222	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
BD01_2223	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BD01_2224	COG1355	regulation of microtubule-based process
BD01_2229	COG1304	FMN binding
BD01_2231	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BD01_2236	COG0495	leucyl-tRNA aminoacylation
BD01_2251	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
BD01_2256	COG0864	Transcriptional regulator
BD01_2259	COG1543	Belongs to the glycosyl hydrolase 57 family
BD01_2262	COG0733	neurotransmitter:sodium symporter activity
BD01_2263	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BD01_2265	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
BD01_2266	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
BD01_2268	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate