locus-tag	class	description
TON_0001	ENOG4105CQ2	DNA polymerase
TON_0001	ENOG4105CQ2	DNA polymerase
TON_0007	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
TON_0011	ENOG4105VUN	Transcriptional regulator
TON_0012	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
TON_0016	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
TON_0017	ENOG4105F4G	Membrane
TON_0020	ENOG4108M11	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
TON_0030	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
TON_0031	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
TON_0037	ENOG4105CJW	magnesium transporter
TON_0038	ENOG4105D9Q	decarboxylase (Beta subunit)
TON_0039	ENOG4107QSA	Oxaloacetate decarboxylase
TON_0041	ENOG4105D8K	carboxyl transferase
TON_0048	ENOG4105CKX	Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP
TON_0052	ENOG4105DPX	Hydrogenase, large subunit
TON_0054	ENOG4105DF0	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity)
TON_0056	ENOG4105CDJ	oxidoreductase FAD NAD(P)-binding domain protein
TON_0057	ENOG4105BZ8	glutamate synthase
TON_0058	ENOG4105C5S	asparaginyl-tRNA synthetase
TON_0061	ENOG4107STF	Involved in phosphonate degradation (By similarity)
TON_0066	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
TON_0068	ENOG4105KZR	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
TON_0069	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
TON_0070	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
TON_0071	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
TON_0072	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
TON_0073	ENOG41082SA	50s ribosomal protein l29
TON_0074	ENOG4108ZJT	translation initiation factor, Sui1
TON_0075	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
TON_0076	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
TON_0079	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
TON_0081	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
TON_0082	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
TON_0085	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
TON_0086	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
TON_0087	ENOG4105VPB	50S ribosomal protein L30
TON_0088	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
TON_0093	ENOG4108Z4J	Cytidine monophosphate kinase
TON_0095	ENOG4108IXY	short-chain dehydrogenase reductase
TON_0096	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
TON_0101	ENOG4107Y49	methyltransferase
TON_0102	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
TON_0103	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
TON_0104	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
TON_0106	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
TON_0107	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
TON_0108	ENOG4108UJD	30S ribosomal protein S9
TON_0112	ENOG4105CE9	30S ribosomal protein S2
TON_0118	ENOG4108YXU	transcriptional regulator AsnC family
TON_0120	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
TON_0128	ENOG4105CB1	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
TON_0131	ENOG4108I5U	Uridine phosphorylase
TON_0132	ENOG41074MP	UPF0103 Mediator of ErbB2-driven cell motility-containing protein
TON_0133	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
TON_0135	ENOG4106UJV	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
TON_0136	ENOG4105CN5	Metallo-Beta-Lactamase
TON_0137	ENOG4105EAH	synthase
TON_0141	ENOG4105C8T	Leucyl-tRNA synthetase
TON_0147	ENOG4108JEB	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
TON_0150	ENOG4105MRR	Transcriptional regulator (By similarity)
TON_0153	ENOG4107RFW	hydrolase family 57
TON_0154	ENOG4108YZA	Nitrogen regulatory protein pii
TON_0156	ENOG4105C8J	)-transporter
TON_0157	ENOG4105D82	Glutamate dehydrogenase
TON_0160	ENOG4108IV0	ABC, transporter
TON_0161	ENOG4105C0Z	ABC transporter
TON_0164	ENOG4105KPK	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation (By similarity)
TON_0165	ENOG4105CY0	Metallo-Beta-Lactamase
TON_0168	ENOG4105E66	phosphoriboisomerase A
TON_0169	ENOG4108T9Q	UPF0278 protein
TON_0176	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
TON_0179	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
TON_0180	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
TON_0184	ENOG4105DHP	deoxycytidine triphosphate deaminase
TON_0189	ENOG4105CX6	glutaminyL-tRNA synthetase
TON_0191	ENOG4107R76	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
TON_0192	ENOG4105C0M	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity)
TON_0193	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
TON_0196	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
TON_0198	ENOG4105DP8	Major facilitator superfamily MFS_1
TON_0200	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
TON_0201	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
TON_0202	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
TON_0214	ENOG4107RGW	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
TON_0217	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
TON_0219	ENOG4107QR0	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
TON_0223	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
TON_0224	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
TON_0231	ENOG4105CHM	Aminotransferase
TON_0237	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
TON_0240	ENOG4105G01	cobalamin (vitamin B12) biosynthesis CbiM protein
TON_0243	ENOG4108JJB	ABC transporter
TON_0247	ENOG4108Y83	glucose-6-phosphate isomerase
TON_0248	ENOG4108Z4T	Peptidase M50
TON_0252	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
TON_0254	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
TON_0255	ENOG4108ESU	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane (By similarity)
TON_0256	ENOG4105S10	periplasmic binding protein
TON_0264	ENOG41083NF	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
TON_0266	ENOG4108JPZ	Monovalent cation H antiporter subunit D
TON_0271	ENOG41069MM	monovalent cation h antiporter subunit g
TON_0274	ENOG4105C47	NADH ubiquinone oxidoreductase 20 kda subunit
TON_0275	ENOG4108RG7	formate hydrogenlyase complex iron-sulfur subunit
TON_0276	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
TON_0277	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
TON_0278	ENOG4108JPZ	Monovalent cation H antiporter subunit D
TON_0279	ENOG4105D65	subunit l
TON_0280	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
TON_0281	ENOG4108IEG	Formate dehydrogenase Alpha subunit
TON_0282	ENOG41067SE	Tetr family transcriptional regulator
TON_0283	ENOG4105WRB	Hydrogenase assembly chaperone hypC hupF
TON_0285	ENOG4105CQS	hydrogenase expression formation protein HypD
TON_0287	ENOG4105C45	hydrogenase expression formation protein (HypE)
TON_0290	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
TON_0296	ENOG4105S10	periplasmic binding protein
TON_0297	ENOG4105EHG	Permease protein
TON_0298	ENOG4105E0A	ABC, transporter
TON_0305	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
TON_0308	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
TON_0312	ENOG4105UQX	Mate efflux family protein
TON_0313	ENOG4105UQX	Mate efflux family protein
TON_0314	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
TON_0315	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
TON_0319	ENOG4108JU3	Alkyl hydroperoxide reductase
TON_0320	ENOG4105ZHF	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
TON_0327	ENOG4105CD5	CoA-binding domain protein
TON_0331	ENOG4106K5Q	Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication (By similarity)
TON_0336	ENOG4108VA3	3-hexulose-6-phosphate synthase
TON_0343	ENOG4105C5S	asparaginyl-tRNA synthetase
TON_0346	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
TON_0348	ENOG4105CH2	amidohydrolase
TON_0352	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
TON_0356	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
TON_0359	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
TON_0361	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
TON_0362	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
TON_0363	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
TON_0364	ENOG4108JJB	ABC transporter
TON_0369	ENOG4105CN9	Peptidase m42 family protein
TON_0372	ENOG4108Z0R	Transferase
TON_0373	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
TON_0376	ENOG4105C22	threonyL-tRNA synthetase
TON_0377	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
TON_0385	ENOG4105F4G	Membrane
TON_0386	ENOG4105EEI	dihydropteroate synthase
TON_0392	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
TON_0393	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
TON_0394	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
TON_0395	ENOG4107TIA	phenylalanyl-tRNA synthetase (beta subunit)
TON_0397	ENOG4105CPQ	Dehydrogenase
TON_0402	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
TON_0403	ENOG4105HDK	L-asparaginase
TON_0409	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
TON_0411	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
TON_0417	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
TON_0419	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
TON_0435	ENOG4105DBV	ornithine carbamoyltransferase
TON_0437	ENOG41087GE	Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity)
TON_0439	ENOG4107S6Z	Na H antiporter
TON_0442	ENOG4105E3H	phosphoglycerate mutase
TON_0443	ENOG4105CV8	reductase
TON_0446	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
TON_0449	ENOG4105BZR	domain protein
TON_0458	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
TON_0462	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
TON_0476	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
TON_0483	ENOG4108JPW	Aminotransferase
TON_0487	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
TON_0488	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
TON_0489	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
TON_0490	ENOG4108IZQ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
TON_0491	ENOG4108JPZ	Monovalent cation H antiporter subunit D
TON_0492	ENOG4108JPZ	Monovalent cation H antiporter subunit D
TON_0493	ENOG4105MKQ	Monovalent cation H antiporter subunit C
TON_0494	ENOG4105D65	subunit l
TON_0496	ENOG4105KJM	monovalent cation h antiporter subunit g
TON_0497	ENOG410684G	monovalent cation H antiporter subunit F
TON_0498	ENOG4105SC1	monovalent cation H antiporter subunit E
TON_0500	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
TON_0501	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
TON_0502	ENOG4108IJ1	Dehydrogenase
TON_0505	ENOG4105C75	arginyL-tRNA synthetase
TON_0506	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
TON_0517	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
TON_0521	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
TON_0523	ENOG4108VVK	transcriptional Regulator, AsnC
TON_0527	ENOG4105KME	endoribonuclease L-psp
TON_0529	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
TON_0530	ENOG4105C3K	feS assembly ATPase SufC
TON_0531	ENOG4105DIW	FeS assembly protein SUFB
TON_0536	ENOG4107SHJ	sulfite reductase subunit b
TON_0538	ENOG4105TMB	Formate nitrite transporter
TON_0539	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
TON_0540	ENOG4105QAX	Iron-sulfur
TON_0541	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
TON_0542	ENOG4105BZ8	glutamate synthase
TON_0543	ENOG4108393	oxidoreductase Fe-S subunit
TON_0546	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
TON_0558	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
TON_0560	ENOG4105DZH	s-adenosylmethionine synthetase (EC 2.5.1.6)
TON_0562	ENOG4107RB4	Cytidine monophosphate kinase
TON_0563	ENOG4105D0M	Protease HtpX homolog
TON_0565	ENOG4105CHM	Aminotransferase
TON_0568	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
TON_0569	ENOG4105C5I	Dehydrogenase
TON_0570	ENOG4105CN9	Peptidase m42 family protein
TON_0573	ENOG4107TSN	permease
TON_0580	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
TON_0583	ENOG4105DQU	oxidoreductase, subunit beta
TON_0584	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
TON_0586	ENOG4105DQU	oxidoreductase, subunit beta
TON_0587	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
TON_0590	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
TON_0592	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
TON_0594	ENOG4105DIH	basic membrane
TON_0595	ENOG4108JQ9	ABC transporter
TON_0596	ENOG4105UIB	(ABC) transporter
TON_0601	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
TON_0602	ENOG4105C8N	cysteinyl-tRNA synthetase
TON_0606	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
TON_0607	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
TON_0608	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
TON_0609	ENOG4108R6K	riboflavin synthase, subunit alpha
TON_0610	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
TON_0612	ENOG4105EHU	Circadian clock protein KaiC
TON_0613	ENOG4107QRT	dEAD DEAH box helicase
TON_0613	ENOG4107QRT	dEAD DEAH box helicase
TON_0615	ENOG4107QJZ	Glycosyl transferase, family 2
TON_0616	ENOG4105CJ3	phosphate transporter
TON_0627	ENOG4105DER	m42 family
TON_0635	ENOG4108WBT	adenosyltransferase
TON_0637	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
TON_0638	ENOG4105CEV	competence damage-inducible protein
TON_0640	ENOG4105E0U	tyrosine-specific transport protein
TON_0641	ENOG4105VZ9	UPF0235 protein
TON_0643	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
TON_0646	ENOG4107QMU	Mate efflux family protein
TON_0648	ENOG4108K3F	N(2),N(2)-dimethylguanosine tRNA methyltransferase
TON_0651	ENOG4105DC7	peptidase M24
TON_0654	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
TON_0659	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
TON_0661	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
TON_0666	ENOG4105C3G	gtp-binding protein
TON_0668	ENOG4107QUT	magnesium and cobalt transport protein CorA
TON_0669	ENOG4105CG9	aspartate racemase
TON_0673	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
TON_0677	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
TON_0678	ENOG4105CIH	Imidazole acetol-phosphate transaminase
TON_0679	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
TON_0684	ENOG4108UHF	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
TON_0685	ENOG4105GSQ	TM1410 hypothetical-related protein
TON_0686	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
TON_0687	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
TON_0688	ENOG4108K7V	UPF0284 protein
TON_0690	ENOG4105EPU	Molybdenum cofactor synthesis domain protein
TON_0691	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
TON_0696	ENOG4105DCI	Phosphohydrolase
TON_0698	ENOG4105KNA	-acetyltransferase
TON_0701	ENOG4105E0R	Deoxyhypusine synthase
TON_0703	ENOG4105CHR	reductase
TON_0705	ENOG4105D0M	Protease HtpX homolog
TON_0710	ENOG4105C8Q	Methyl-accepting chemotaxis
TON_0711	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
TON_0713	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
TON_0716	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
TON_0718	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
TON_0724	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
TON_0725	ENOG4108I5C	dEAD DEAH box helicase
TON_0727	ENOG4105FDK	ABC transporter
TON_0748	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
TON_0749	ENOG4105WE2	aldehyde ferredoxin oxidoreductase
TON_0751	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
TON_0752	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
TON_0755	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
TON_0756	ENOG4105DCI	Phosphohydrolase
TON_0757	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
TON_0764	ENOG41065SU	Two-component system sensor kinase
TON_0768	ENOG4105FDK	ABC transporter
TON_0770	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
TON_0774	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
TON_0777	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
TON_0780	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
TON_0783	ENOG4107QTZ	amino acid
TON_0786	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
TON_0795	ENOG4105WMR	Protein CrcB homolog
TON_0796	ENOG4105KJJ	Uncharacterized ACR, COG1993
TON_0798	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
TON_0799	ENOG4105D64	Mechanosensitive ion channel
TON_0807	ENOG41079KZ	Major Facilitator Superfamily
TON_0814	ENOG4105CPK	Glycosyl transferase (Group 1
TON_0817	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
TON_0819	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
TON_0821	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
TON_0828	ENOG4108J2R	molybdopterin oxidoreductase
TON_0829	ENOG4105D3R	alkyl hydroperoxide reductase
TON_0834	ENOG4105SZ6	Thioredoxin
TON_0835	ENOG4105C59	p-type ATPase
TON_0838	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
TON_0846	ENOG4105EKT	)-iron permease
TON_0847	ENOG4105D3R	alkyl hydroperoxide reductase
TON_0851	ENOG4105C3K	feS assembly ATPase SufC
TON_0853	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
TON_0854	ENOG4105D06	uba thif-type nad fad binding protein
TON_0855	ENOG4107Y03	Nitroreductase
TON_0861	ENOG4105DQU	oxidoreductase, subunit beta
TON_0862	ENOG4105D3R	alkyl hydroperoxide reductase
TON_0863	ENOG4105CNW	domain protein
TON_0865	ENOG4107QZF	nitrite reductase NADPH large subunit
TON_0866	ENOG4108RAC	Rubrerythrin
TON_0867	ENOG4105VCQ	rubredoxin
TON_0868	ENOG4108YZ8	Superoxide reductase
TON_0879	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
TON_0881	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
TON_0882	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
TON_0883	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
TON_0884	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
TON_0885	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
TON_0886	ENOG4105CIH	Imidazole acetol-phosphate transaminase
TON_0889	ENOG4105EHU	Circadian clock protein KaiC
TON_0893	ENOG410695F	Crispr-associated protein, Csm1 family
TON_0895	ENOG4108W8W	CRISPR-associated RAMP protein, Csm3 family
TON_0899	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
TON_0901	ENOG4105CK2	sodium dicarboxylate symporter
TON_0904	ENOG4107QSA	Oxaloacetate decarboxylase
TON_0905	ENOG4105D22	carbon starvation protein
TON_0910	ENOG4105E5G	Alpha beta hydrolase fold
TON_0911	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
TON_0915	ENOG4107QMS	site-determining protein
TON_0923	ENOG4105CHR	reductase
TON_0928	ENOG4105VYW	UPF0251 protein
TON_0929	ENOG4105C83	adenylosuccinate lyase
TON_0934	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
TON_0937	ENOG4107QRT	dEAD DEAH box helicase
TON_0938	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
TON_0939	ENOG4105C5X	domain protein
TON_0941	ENOG4105F8V	Hydrolase, tatD family
TON_0945	ENOG4105C5I	Dehydrogenase
TON_0946	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
TON_0947	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
TON_0948	ENOG4107EEM	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
TON_0951	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
TON_0957	ENOG4105C11	sulfate adenylyltransferase), subunit 2
TON_0960	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
TON_0961	ENOG4105C5S	asparaginyl-tRNA synthetase
TON_0963	ENOG4105DP9	ABC transporter
TON_0968	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
TON_0969	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
TON_0973	ENOG4105VKD	bioY protein
TON_0974	ENOG4108JJB	ABC transporter
TON_0975	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
TON_0984	ENOG4107QVT	Binding-protein-dependent transport systems, inner membrane component
TON_0985	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
TON_0987	ENOG41088CQ	domain protein
TON_0990	ENOG4105BZA	Phosphoglycerate kinase
TON_0996	ENOG4105CSM	endonuclease III
TON_1002	ENOG4105CD5	CoA-binding domain protein
TON_1004	ENOG4105C6T	cysteine synthase
TON_1006	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
TON_1008	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
TON_1013	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
TON_1015	ENOG4105PW4	Sugar fermentation stimulation protein homolog
TON_1017	ENOG4105QAX	Iron-sulfur
TON_1018	ENOG4105CJG	carbon-monoxide dehydrogenase catalytic subunit
TON_1019	ENOG4107QMS	site-determining protein
TON_1021	ENOG4108JPZ	Monovalent cation H antiporter subunit D
TON_1022	ENOG4107TDF	Formate hydrogenlyase subunit 4
TON_1023	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
TON_1024	ENOG4105C47	NADH ubiquinone oxidoreductase 20 kda subunit
TON_1026	ENOG4105KJM	monovalent cation h antiporter subunit g
TON_1028	ENOG4108PMQ	Na H antiporter MnhB subunit-related protein
TON_1031	ENOG4108JPZ	Monovalent cation H antiporter subunit D
TON_1032	ENOG4105CN9	Peptidase m42 family protein
TON_1037	ENOG4105CIG	ABC transporter
TON_1040	ENOG4105DVT	helicase
TON_1042	ENOG4105C1J	atp-dependent rna helicase
TON_1045	ENOG4105ECY	inositol monophosphatase
TON_1047	ENOG4108I6A	alcohol dehydrogenase
TON_1050	ENOG4105P4J	Allophanate hydrolase, subunit 1
TON_1051	ENOG4105E7W	lamb ycsf family protein
TON_1058	ENOG4107QX8	SPFH domain, Band 7 family protein
TON_1059	ENOG4107QMS	site-determining protein
TON_1062	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
TON_1065	ENOG4108RCS	geranylgeranylglyceryl phosphate synthase
TON_1069	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
TON_1071	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
TON_1072	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
TON_1076	ENOG4105D5P	Methylmalonyl-coA mutase
TON_1078	ENOG4108Z03	MAF-like protein
TON_1080	ENOG4105CTP	PilT protein domain protein
TON_1083	ENOG4105CAQ	asparagine synthetase
TON_1086	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
TON_1090	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
TON_1091	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
TON_1094	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
TON_1097	ENOG4105CD5	CoA-binding domain protein
TON_1113	ENOG4107Y70	Heat shock protein
TON_1128	ENOG4108TVJ	Nitroreductase
TON_1132	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
TON_1133	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
TON_1134	ENOG4105D49	3-dehydroquinate synthase
TON_1136	ENOG4105E2X	shikimate dehydrogenase
TON_1137	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
TON_1138	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
TON_1139	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
TON_1140	ENOG4105CQC	Prephenate dehydratase
TON_1141	ENOG4105CHM	Aminotransferase
TON_1143	ENOG410641W	Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protein includes tyrosine phosphatase and GTPase activating protein (GAP) activities. After bacterial internalization, GAP mediates the reversal of the cytoskeletal changes induced by SopE. This function is independent of its tyrosine phosphatase activity, which remains unclear
TON_1156	ENOG4108WVK	Could be a S-adenosyl-L-methionine-dependent methyltransferase (By similarity)
TON_1161	ENOG4105EAC	phosphoserine phosphatase
TON_1175	ENOG4105EAC	phosphoserine phosphatase
TON_1176	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
TON_1190	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
TON_1193	ENOG4108V3W	Chemotaxis protein, CheW
TON_1194	ENOG4105C8Q	Methyl-accepting chemotaxis
TON_1195	ENOG4105BZU	Histidine kinase
TON_1196	ENOG4107YTP	response regulator receiver protein
TON_1197	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
TON_1198	ENOG4105CBS	Chea signal transduction histidine kinase
TON_1201	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
TON_1202	ENOG4105C8Q	Methyl-accepting chemotaxis
TON_1211	ENOG4106IPI	cyclase, family
TON_1212	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
TON_1214	ENOG4108R96	Methyltransferase, YaeB family
TON_1217	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
TON_1218	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
TON_1228	ENOG4105D1Z	hydroxypyruvate reductase
TON_1232	ENOG4108IYI	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
TON_1233	ENOG4107104	thymidine kinase
TON_1234	ENOG4105DT1	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate
TON_1243	ENOG4105CJ1	ABC, transporter
TON_1248	ENOG4108Y5D	Inherit from COG: cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
TON_1251	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
TON_1253	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
TON_1255	ENOG4107QJE	Chromosome Partitioning Protein
TON_1256	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
TON_1259	ENOG4105CHM	Aminotransferase
TON_1263	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
TON_1264	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
TON_1268	ENOG41080HI	glycine oxidase
TON_1270	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
TON_1271	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
TON_1276	ENOG4105D0M	Protease HtpX homolog
TON_1279	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
TON_1280	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
TON_1283	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
TON_1285	ENOG4108Z0Z	intracellular protease Pfpi family
TON_1291	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
TON_1292	ENOG4108UKZ	OsmC family
TON_1295	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
TON_1296	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
TON_1301	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
TON_1302	ENOG4105CHU	acetyl-coa acetyltransferase
TON_1314	ENOG4107WCI	zn-dependent hydrolase of the beta-lactamase fold-like protein
TON_1321	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
TON_1322	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
TON_1325	ENOG4108ZP8	Acetolactate synthase small subunit
TON_1326	ENOG4108JPZ	Monovalent cation H antiporter subunit D
TON_1331	ENOG4105KJM	monovalent cation h antiporter subunit g
TON_1333	ENOG4105SC1	monovalent cation H antiporter subunit E
TON_1334	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
TON_1336	ENOG4105BZ8	glutamate synthase
TON_1337	ENOG4105CDJ	oxidoreductase FAD NAD(P)-binding domain protein
TON_1348	ENOG4105CJ1	ABC, transporter
TON_1349	ENOG4105VZ8	Transcriptional regulator
TON_1353	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
TON_1354	ENOG4105WE2	aldehyde ferredoxin oxidoreductase
TON_1355	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
TON_1358	ENOG4108JVH	Protein of unknown function DUF43
TON_1360	ENOG4105VG1	fes assembly suf system protein
TON_1361	ENOG41084T3	4fe-4S ferredoxin iron-sulfur binding domain-containing protein
TON_1368	ENOG4108UK2	deaminase
TON_1369	ENOG4105D0M	Protease HtpX homolog
TON_1375	ENOG4105CDJ	oxidoreductase FAD NAD(P)-binding domain protein
TON_1376	ENOG4105BZ8	glutamate synthase
TON_1380	ENOG4107QKA	exodeoxyribonuclease V beta
TON_1385	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
TON_1386	ENOG41079KZ	Major Facilitator Superfamily
TON_1391	ENOG4105C6X	Major Facilitator
TON_1392	ENOG4105D44	asparaginase
TON_1397	ENOG4105DK7	lysyl-tRNA synthetase
TON_1403	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
TON_1407	ENOG4105EHU	Circadian clock protein KaiC
TON_1410	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
TON_1414	ENOG4105C6E	dna polymerase iii
TON_1415	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
TON_1422	ENOG4107WZZ	SMC domain protein
TON_1422	ENOG4107WZZ	SMC domain protein
TON_1424	ENOG4105EHG	Permease protein
TON_1425	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
TON_1426	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
TON_1428	ENOG4108IYI	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
TON_1431	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
TON_1436	ENOG4107ZCS	Phosphomethylpyrimidine kinase
TON_1437	ENOG4105CXT	aspartate transcarbamylase
TON_1438	ENOG4108R9M	Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity)
TON_1445	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
TON_1454	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
TON_1455	ENOG41080HT	Transcriptional regulator, arsr family
TON_1458	ENOG4108J9M	Transporter
TON_1465	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
TON_1466	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
TON_1470	ENOG4107RWR	Sodium hydrogen exchanger
TON_1474	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
TON_1475	ENOG4105CJ3	phosphate transporter
TON_1478	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
TON_1479	ENOG4105DDK	oxidoreductase, beta subunit
TON_1481	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
TON_1482	ENOG4105DDK	oxidoreductase, beta subunit
TON_1483	ENOG4105D1F	ATP-binding protein
TON_1488	ENOG4108RVA	ribokinase
TON_1490	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
TON_1492	ENOG4108UUC	Protein of unknown function DUF99
TON_1493	ENOG4107YZX	Universal stress protein
TON_1494	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
TON_1497	ENOG4107NFR	Fructose-1,6-bisphosphatase
TON_1501	ENOG4105EWK	phytoene
TON_1509	ENOG4107UX3	phosphatidylethanolamine N-methyltransferase
TON_1510	ENOG4108VVK	transcriptional Regulator, AsnC
TON_1511	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
TON_1513	ENOG4107SW0	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
TON_1517	ENOG4107S6Z	Na H antiporter
TON_1518	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
TON_1523	ENOG4105VAW	lrga family
TON_1524	ENOG41067MG	lrgb family
TON_1527	ENOG4108S8N	class II Aldolase
TON_1529	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
TON_1532	ENOG4107S5Z	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity)
TON_1533	ENOG4105VFR	signal peptidase
TON_1536	ENOG4108IGT	Dipeptidase
TON_1543	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
TON_1552	ENOG4107QXV	Phosphate transporter
TON_1557	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
TON_1558	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
TON_1562	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
TON_1563	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
TON_1564	ENOG4105D3S	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
TON_1565	ENOG4105D65	subunit l
TON_1566	ENOG4108JPZ	Monovalent cation H antiporter subunit D
TON_1567	ENOG4107R30	NADH dehydrogenase
TON_1568	ENOG4107TDF	Formate hydrogenlyase subunit 4
TON_1569	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
TON_1570	ENOG4108RG7	formate hydrogenlyase complex iron-sulfur subunit
TON_1571	ENOG4105C47	NADH ubiquinone oxidoreductase 20 kda subunit
TON_1573	ENOG4105TMB	Formate nitrite transporter
TON_1575	ENOG4105KJM	monovalent cation h antiporter subunit g
TON_1577	ENOG4108PMQ	Na H antiporter MnhB subunit-related protein
TON_1580	ENOG4108JPZ	Monovalent cation H antiporter subunit D
TON_1581	ENOG41083NF	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
TON_1582	ENOG4105SC1	monovalent cation H antiporter subunit E
TON_1584	ENOG4105KJM	monovalent cation h antiporter subunit g
TON_1589	ENOG4108JPZ	Monovalent cation H antiporter subunit D
TON_1591	ENOG4105C47	NADH ubiquinone oxidoreductase 20 kda subunit
TON_1592	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
TON_1593	ENOG4108HM5	NADH-ubiquinone oxidoreductase chain 49kDa
TON_1594	ENOG4107TDF	Formate hydrogenlyase subunit 4
TON_1603	ENOG4105C3M	thioredoxin reductase
TON_1605	ENOG4108JPW	Aminotransferase
TON_1608	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
TON_1611	ENOG4105F22	Major Facilitator Superfamily
TON_1612	ENOG4107ZBH	radical SAM domain protein
TON_1613	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
TON_1615	ENOG4108VVK	transcriptional Regulator, AsnC
TON_1616	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
TON_1620	ENOG4108ZAF	Molybdopterin
TON_1622	ENOG4105D06	uba thif-type nad fad binding protein
TON_1630	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
TON_1632	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
TON_1634	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
TON_1646	ENOG4105EYW	Ion transport protein
TON_1651	ENOG4105CB1	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
TON_1653	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
TON_1655	ENOG4105D1H	recombination factor protein RarA
TON_1659	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
TON_1660	ENOG4105E5K	Alpha-amylase
TON_1663	ENOG41082SX	arsR family transcriptional regulator
TON_1664	ENOG4107QWE	)-transporter
TON_1666	ENOG4105C31	Tryptophanyl-tRNA synthetase
TON_1667	ENOG4105ERH	Fumarylacetoacetate hydrolase
TON_1671	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
TON_1672	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
TON_1678	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
TON_1683	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
TON_1686	ENOG4107Y7Q	pfkb domain protein
TON_1687	ENOG4105CTD	carboxy-peptidase
TON_1689	ENOG4107SCK	Monooxygenase
TON_1690	ENOG4108KN7	Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity)
TON_1692	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
TON_1694	ENOG4105DZP	Membrane-associated zinc metalloprotease
TON_1696	ENOG4105CBG	Sulfatase
TON_1699	ENOG4108UW5	maltose o-acetyltransferase
TON_1700	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
TON_1701	ENOG4105C5E	polysaccharide biosynthesis protein
TON_1703	ENOG4107TSN	permease
TON_1704	ENOG4107T1U	Catalyzes the synthesis of activated sulfate (By similarity)
TON_1707	ENOG4107RIQ	Sulfate adenylate transferase
TON_1716	ENOG4105C6W	4-alpha-glucanotransferase (EC 2.4.1.25)
TON_1717	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
TON_1718	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
TON_1719	ENOG4105CJW	magnesium transporter
TON_1720	ENOG4107RWR	Sodium hydrogen exchanger
TON_1722	ENOG4105CUT	histidyl-tRNA synthetase
TON_1729	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
TON_1732	ENOG4107XF7	NGG1p interacting factor 3 protein, NIF3
TON_1740	ENOG4105EHU	Circadian clock protein KaiC
TON_1742	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
TON_1743	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
TON_1745	ENOG4105C1A	potassium transporter peripheral membrane
TON_1749	ENOG4105K4G	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
TON_1751	ENOG4105KXQ	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
TON_1752	ENOG4108JIQ	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit (By similarity)
TON_1754	ENOG4105M56	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
TON_1756	ENOG4105EC8	Methyl-accepting chemotaxis
TON_1757	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
TON_1758	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
TON_1763	ENOG4105CD3	dihydroorotase
TON_1766	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
TON_1767	ENOG4105C3U	ABC transporter
TON_1768	ENOG4108JQ7	(ABC) transporter
TON_1770	ENOG4105C4K	Nad synthetase
TON_1772	ENOG4105C5F	glutamine synthetase
TON_1779	ENOG4105EHU	Circadian clock protein KaiC
TON_1783	ENOG4105DR4	Methyltransferase
TON_1784	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
TON_1785	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
TON_1787	ENOG4105EPD	Oligopeptide transporter, Opt family
TON_1793	ENOG4105EG2	ABC transporter, permease
TON_1795	ENOG4107FKK	extracellular solute-binding protein family 1
TON_1797	ENOG4108NGU	Transcriptional regulator
TON_1803	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
TON_1805	ENOG4108594	Permease of the drug metabolite transporter
TON_1807	ENOG4105WE2	aldehyde ferredoxin oxidoreductase
TON_1813	ENOG41081HM	2'-5' rna ligase
TON_1816	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
TON_1821	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
TON_1823	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
TON_1831	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
TON_1837	ENOG4105CNB	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
TON_1842	ENOG4107V9E	glucose-1-phosphate thymidylyltransferase
TON_1848	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
TON_1855	ENOG4107RA4	Glycosyl transferase (Group 1
TON_1856	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
TON_1857	ENOG4105CPK	Glycosyl transferase (Group 1
TON_1860	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
TON_1862	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
TON_1870	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
TON_1873	ENOG4105EHG	Permease protein
TON_1874	ENOG4108HWH	(ABC) transporter
TON_1875	ENOG4105CTK	cobaltochelatase, cobn subunit
TON_1876	ENOG4105EET	magnesium chelatase
TON_1877	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
TON_1884	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
TON_1885	ENOG4108IYU	L-aspartate oxidase
TON_1887	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
TON_1889	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
TON_1890	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
TON_1891	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
TON_1893	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
TON_1894	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
TON_1906	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
TON_1913	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
TON_1914	ENOG4105F0N	pyrophosphate phospho-hydrolase
TON_1919	ENOG4105IIU	Aminopeptidase
TON_1933	ENOG4105K8R	UPF0145 protein
TON_1935	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
TON_1939	ENOG4105D8X	mechanosensitive ion channel
TON_1944	ENOG4105EM7	Selenocysteine-specific translation elongation factor
TON_1948	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
TON_1950	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
TON_1957	ENOG4105C7N	Xanthine uracil vitamin C permease
TON_1958	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
TON_1959	ENOG4106SMU	thiamine transporter membrane protein
TON_1965	ENOG4105NBF	ammecr1 domain protein
TON_1966	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
TON_1968	ENOG4108RWI	nicotinamidase
TON_1972	ENOG4108MIC	Mg-protoporphyrin IX methyl transferase
TON_1973	ENOG4108Z86	Glutamine amidotransferase
TON_1976	ENOG410825M	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)