TON_1376 d93cf2549c41f0b5d2f1821d09a76b61 482 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 402 416 1.2E-15 T 23-10-2018 TON_1376 d93cf2549c41f0b5d2f1821d09a76b61 482 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 444 451 1.2E-15 T 23-10-2018 TON_1376 d93cf2549c41f0b5d2f1821d09a76b61 482 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 299 324 1.2E-15 T 23-10-2018 TON_1376 d93cf2549c41f0b5d2f1821d09a76b61 482 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 160 182 1.2E-15 T 23-10-2018 TON_1376 d93cf2549c41f0b5d2f1821d09a76b61 482 SUPERFAMILY SSF46548 10 169 1.36E-31 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 TON_1376 d93cf2549c41f0b5d2f1821d09a76b61 482 SUPERFAMILY SSF51971 159 409 1.77E-70 T 23-10-2018 TON_1376 d93cf2549c41f0b5d2f1821d09a76b61 482 Gene3D G3DSA:3.50.50.60 156 286 3.5E-38 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TON_1376 d93cf2549c41f0b5d2f1821d09a76b61 482 Gene3D G3DSA:3.50.50.60 295 482 2.6E-33 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TON_1376 d93cf2549c41f0b5d2f1821d09a76b61 482 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 160 460 2.1E-41 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TON_1376 d93cf2549c41f0b5d2f1821d09a76b61 482 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 24 141 1.2E-38 T 23-10-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 TON_1376 d93cf2549c41f0b5d2f1821d09a76b61 482 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 401 417 3.3E-22 T 23-10-2018 TON_1376 d93cf2549c41f0b5d2f1821d09a76b61 482 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 299 317 3.3E-22 T 23-10-2018 TON_1376 d93cf2549c41f0b5d2f1821d09a76b61 482 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 429 451 3.3E-22 T 23-10-2018 TON_1376 d93cf2549c41f0b5d2f1821d09a76b61 482 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 244 262 3.3E-22 T 23-10-2018 TON_1376 d93cf2549c41f0b5d2f1821d09a76b61 482 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 161 180 3.3E-22 T 23-10-2018 TON_1376 d93cf2549c41f0b5d2f1821d09a76b61 482 Gene3D G3DSA:1.10.1060.10 7 150 3.6E-39 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 TON_1376 d93cf2549c41f0b5d2f1821d09a76b61 482 TIGRFAM TIGR01316 gltA: glutamate synthase (NADPH), homotetrameric 19 475 9.7E-220 T 23-10-2018 IPR006004 Glutamate synthase (NADPH), homotetrameric KEGG: 00195+1.18.1.2|MetaCyc: PWY-101 TON_1199 6f6c7cffa70f24455405b57232080e8d 210 SUPERFAMILY SSF103039 12 205 1.57E-47 T 23-10-2018 IPR028976 CheC-like superfamily TON_1199 6f6c7cffa70f24455405b57232080e8d 210 Pfam PF04509 CheC-like family 113 148 1.9E-9 T 23-10-2018 IPR007597 CheC-like protein GO:0016787 TON_1199 6f6c7cffa70f24455405b57232080e8d 210 Pfam PF04509 CheC-like family 17 51 8.2E-7 T 23-10-2018 IPR007597 CheC-like protein GO:0016787 TON_1199 6f6c7cffa70f24455405b57232080e8d 210 Gene3D G3DSA:3.40.1550.10 11 206 1.5E-53 T 23-10-2018 IPR028976 CheC-like superfamily TON_1264 ebc5a9af907acd5d3c49315f24655f9e 300 Gene3D G3DSA:2.30.26.10 55 212 7.5E-93 T 23-10-2018 IPR023359 Dihydroorotate dehydrogenase A, chain A, domain 2 TON_1264 ebc5a9af907acd5d3c49315f24655f9e 300 Pfam PF01180 Dihydroorotate dehydrogenase 4 283 5.7E-64 T 23-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 TON_1264 ebc5a9af907acd5d3c49315f24655f9e 300 PIRSF PIRSF000164 1 300 9.3E-88 T 23-10-2018 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 TON_1264 ebc5a9af907acd5d3c49315f24655f9e 300 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 235 255 - T 23-10-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 TON_1264 ebc5a9af907acd5d3c49315f24655f9e 300 Hamap MF_00224 Dihydroorotate dehydrogenase [pyrD]. 4 298 36.996 T 23-10-2018 IPR024920 Dihydroorotate dehydrogenase, class 1 GO:0004152|GO:0005737|GO:0006221 TON_1264 ebc5a9af907acd5d3c49315f24655f9e 300 TIGRFAM TIGR01037 pyrD_sub1_fam: dihydroorotate dehydrogenase family protein 5 298 4.0E-128 T 23-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 TON_1264 ebc5a9af907acd5d3c49315f24655f9e 300 Gene3D G3DSA:3.20.20.70 12 289 7.5E-93 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TON_1264 ebc5a9af907acd5d3c49315f24655f9e 300 ProSitePatterns PS00911 Dihydroorotate dehydrogenase signature 1. 40 59 - T 23-10-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 TON_1264 ebc5a9af907acd5d3c49315f24655f9e 300 SUPERFAMILY SSF51395 2 298 7.99E-84 T 23-10-2018 TON_1133 1248af4ead3a0984c105c2e1019c1e2c 266 TIGRFAM TIGR01361 DAHP_synth_Bsub: 3-deoxy-7-phosphoheptulonate synthase 8 260 4.8E-126 T 23-10-2018 IPR006268 Phospho-2-dehydro-3-deoxyheptonate aldolase, subtype 2 GO:0009073|GO:0016832 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 TON_1133 1248af4ead3a0984c105c2e1019c1e2c 266 Gene3D G3DSA:3.20.20.70 5 266 1.2E-107 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TON_1133 1248af4ead3a0984c105c2e1019c1e2c 266 Pfam PF00793 DAHP synthetase I family 20 258 3.1E-77 T 23-10-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 TON_1133 1248af4ead3a0984c105c2e1019c1e2c 266 SUPERFAMILY SSF51569 12 259 4.85E-96 T 23-10-2018 TON_0997 38c23c0a87b7293db661d7f13383328d 192 Gene3D G3DSA:3.30.70.1450 111 192 1.1E-19 T 23-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 TON_0997 38c23c0a87b7293db661d7f13383328d 192 SUPERFAMILY SSF109755 2 98 4.71E-15 T 23-10-2018 TON_0997 38c23c0a87b7293db661d7f13383328d 192 Pfam PF02080 TrkA-C domain 118 176 3.5E-16 T 23-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 TON_0997 38c23c0a87b7293db661d7f13383328d 192 Pfam PF01895 PhoU domain 11 94 2.1E-8 T 23-10-2018 IPR026022 PhoU domain TON_0997 38c23c0a87b7293db661d7f13383328d 192 SUPERFAMILY SSF116726 102 182 1.7E-18 T 23-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 TON_0997 38c23c0a87b7293db661d7f13383328d 192 Gene3D G3DSA:1.20.58.220 1 110 2.7E-19 T 23-10-2018 IPR038078 PhoU-like domain superfamily TON_1143 7f3ea1cc66773705cb9aa580cf781c8a 147 ProSitePatterns PS00383 Tyrosine specific protein phosphatases active site. 89 99 - T 23-10-2018 IPR016130 Protein-tyrosine phosphatase, active site GO:0004725|GO:0016311 TON_1143 7f3ea1cc66773705cb9aa580cf781c8a 147 SMART SM00404 50 144 1.0E-6 T 23-10-2018 IPR003595 Protein-tyrosine phosphatase, catalytic TON_1143 7f3ea1cc66773705cb9aa580cf781c8a 147 Gene3D G3DSA:3.90.190.10 7 147 5.0E-34 T 23-10-2018 IPR029021 Protein-tyrosine phosphatase-like TON_1143 7f3ea1cc66773705cb9aa580cf781c8a 147 SMART SM00195 11 144 8.3E-6 T 23-10-2018 IPR020422 Dual specificity protein phosphatase domain GO:0006470|GO:0008138 TON_1143 7f3ea1cc66773705cb9aa580cf781c8a 147 Pfam PF00782 Dual specificity phosphatase, catalytic domain 26 141 1.4E-16 T 23-10-2018 IPR000340 Dual specificity phosphatase, catalytic domain GO:0008138|GO:0016311 TON_1143 7f3ea1cc66773705cb9aa580cf781c8a 147 SUPERFAMILY SSF52799 27 146 8.3E-35 T 23-10-2018 IPR029021 Protein-tyrosine phosphatase-like TON_0395 461c3e084e5b5e89eb19971cbb886480 572 SMART SM00874 280 348 4.4E-17 T 23-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 TON_0395 461c3e084e5b5e89eb19971cbb886480 572 TIGRFAM TIGR00471 pheT_arch: phenylalanine--tRNA ligase, beta subunit 1 562 3.8E-178 T 23-10-2018 IPR004531 Phenylalanyl-tRNA synthetase, class IIc, beta subunit, archae/euk cytosolic GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 TON_0395 461c3e084e5b5e89eb19971cbb886480 572 SUPERFAMILY SSF46955 5 80 2.93E-8 T 23-10-2018 IPR009061 Putative DNA-binding domain superfamily TON_0395 461c3e084e5b5e89eb19971cbb886480 572 SUPERFAMILY SSF55681 345 566 2.07E-43 T 23-10-2018 TON_0395 461c3e084e5b5e89eb19971cbb886480 572 Gene3D G3DSA:3.30.56.10 279 348 1.2E-26 T 23-10-2018 TON_0395 461c3e084e5b5e89eb19971cbb886480 572 Pfam PF03484 tRNA synthetase B5 domain 284 348 8.6E-15 T 23-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 TON_0395 461c3e084e5b5e89eb19971cbb886480 572 Gene3D G3DSA:3.30.930.10 367 566 8.3E-50 T 23-10-2018 TON_0395 461c3e084e5b5e89eb19971cbb886480 572 Gene3D G3DSA:3.30.56.10 1 80 7.8E-22 T 23-10-2018 TON_0395 461c3e084e5b5e89eb19971cbb886480 572 SUPERFAMILY SSF46955 281 352 4.67E-16 T 23-10-2018 IPR009061 Putative DNA-binding domain superfamily TON_0395 461c3e084e5b5e89eb19971cbb886480 572 Pfam PF03483 B3/4 domain 120 244 4.7E-16 T 23-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 TON_0395 461c3e084e5b5e89eb19971cbb886480 572 SMART SM00873 100 259 2.5E-21 T 23-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 TON_0395 461c3e084e5b5e89eb19971cbb886480 572 SUPERFAMILY SSF56037 142 260 1.88E-5 T 23-10-2018 TON_0395 461c3e084e5b5e89eb19971cbb886480 572 Hamap MF_00284 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 564 35.867 T 23-10-2018 IPR022918 Phenylalanine-tRNA ligase beta chain 2, bacterial/archaeal GO:0004826 KEGG: 00970+6.1.1.20 TON_0395 461c3e084e5b5e89eb19971cbb886480 572 Gene3D G3DSA:3.50.40.10 81 278 5.6E-74 T 23-10-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 KEGG: 00970+6.1.1.20 TON_0435 827b70f05ffb6e25c82b7de80e5dc49c 315 PRINTS PR00102 Ornithine carbamoyltransferase signature 124 138 1.8E-30 T 23-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 TON_0435 827b70f05ffb6e25c82b7de80e5dc49c 315 PRINTS PR00102 Ornithine carbamoyltransferase signature 84 97 1.8E-30 T 23-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 TON_0435 827b70f05ffb6e25c82b7de80e5dc49c 315 PRINTS PR00102 Ornithine carbamoyltransferase signature 227 237 1.8E-30 T 23-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 TON_0435 827b70f05ffb6e25c82b7de80e5dc49c 315 PRINTS PR00102 Ornithine carbamoyltransferase signature 51 65 1.8E-30 T 23-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 TON_0435 827b70f05ffb6e25c82b7de80e5dc49c 315 PRINTS PR00102 Ornithine carbamoyltransferase signature 289 300 1.8E-30 T 23-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 TON_0435 827b70f05ffb6e25c82b7de80e5dc49c 315 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 7 311 85.508 T 23-10-2018 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 TON_0435 827b70f05ffb6e25c82b7de80e5dc49c 315 Gene3D G3DSA:3.40.50.1370 9 307 2.9E-138 T 23-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 TON_0435 827b70f05ffb6e25c82b7de80e5dc49c 315 Gene3D G3DSA:3.40.50.1370 138 297 2.9E-138 T 23-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 TON_0435 827b70f05ffb6e25c82b7de80e5dc49c 315 SUPERFAMILY SSF53671 4 313 1.26E-116 T 23-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 TON_0435 827b70f05ffb6e25c82b7de80e5dc49c 315 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 8 310 2.1E-145 T 23-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 TON_0435 827b70f05ffb6e25c82b7de80e5dc49c 315 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 154 308 9.2E-66 T 23-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 TON_0435 827b70f05ffb6e25c82b7de80e5dc49c 315 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 53 60 - T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TON_0435 827b70f05ffb6e25c82b7de80e5dc49c 315 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 135 146 1.8E-29 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TON_0435 827b70f05ffb6e25c82b7de80e5dc49c 315 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 275 298 1.8E-29 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TON_0435 827b70f05ffb6e25c82b7de80e5dc49c 315 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 53 72 1.8E-29 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TON_0435 827b70f05ffb6e25c82b7de80e5dc49c 315 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 263 272 1.8E-29 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TON_0435 827b70f05ffb6e25c82b7de80e5dc49c 315 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 8 148 1.4E-50 T 23-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 TON_1666 5ab71f4b48a366d462b5d1dcb0f0fcc7 384 Hamap MF_00140_A Tryptophan--tRNA ligase [trpS]. 5 366 46.628 T 23-10-2018 IPR020653 Tryptophan-tRNA ligase, archaea GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 TON_1666 5ab71f4b48a366d462b5d1dcb0f0fcc7 384 Gene3D G3DSA:3.40.50.620 1 255 1.2E-102 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TON_1666 5ab71f4b48a366d462b5d1dcb0f0fcc7 384 SUPERFAMILY SSF52374 4 368 1.48E-90 T 23-10-2018 TON_1666 5ab71f4b48a366d462b5d1dcb0f0fcc7 384 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 81 90 - T 23-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 TON_1666 5ab71f4b48a366d462b5d1dcb0f0fcc7 384 Gene3D G3DSA:1.10.240.10 256 383 1.3E-45 T 23-10-2018 TON_1666 5ab71f4b48a366d462b5d1dcb0f0fcc7 384 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 72 381 5.6E-106 T 23-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 TON_1666 5ab71f4b48a366d462b5d1dcb0f0fcc7 384 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 208 229 3.5E-20 T 23-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 TON_1666 5ab71f4b48a366d462b5d1dcb0f0fcc7 384 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 85 101 3.5E-20 T 23-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 TON_1666 5ab71f4b48a366d462b5d1dcb0f0fcc7 384 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 138 157 3.5E-20 T 23-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 TON_1666 5ab71f4b48a366d462b5d1dcb0f0fcc7 384 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 252 262 3.5E-20 T 23-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 TON_1666 5ab71f4b48a366d462b5d1dcb0f0fcc7 384 Pfam PF00579 tRNA synthetases class I (W and Y) 73 347 9.0E-26 T 23-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 TON_0583 b09c5faded2f4352aaefe0c8686e5563 281 Gene3D G3DSA:3.40.50.970 74 250 2.0E-28 T 23-10-2018 TON_0583 b09c5faded2f4352aaefe0c8686e5563 281 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 56 202 5.3E-35 T 23-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 TON_0583 b09c5faded2f4352aaefe0c8686e5563 281 SUPERFAMILY SSF52518 19 271 9.32E-75 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold TON_1466 4012c9c28b4ec72c1c9874f459e5fef0 239 SUPERFAMILY SSF75217 2 177 8.5E-33 T 23-10-2018 IPR029028 Alpha/beta knot methyltransferases TON_1466 4012c9c28b4ec72c1c9874f459e5fef0 239 TIGRFAM TIGR00050 rRNA_methyl_1: RNA methyltransferase, TrmH family, group 1 2 226 5.8E-64 T 23-10-2018 IPR004384 RNA methyltransferase TrmJ/LasT GO:0006396|GO:0008173 TON_1466 4012c9c28b4ec72c1c9874f459e5fef0 239 Pfam PF00588 SpoU rRNA Methylase family 3 151 1.1E-32 T 23-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 TON_1466 4012c9c28b4ec72c1c9874f459e5fef0 239 PIRSF PIRSF004808 1 236 1.6E-74 T 23-10-2018 IPR004384 RNA methyltransferase TrmJ/LasT GO:0006396|GO:0008173 TON_1466 4012c9c28b4ec72c1c9874f459e5fef0 239 Gene3D G3DSA:3.40.1280.10 1 158 1.3E-49 T 23-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal TON_0154 53774793e415edcb8875539b5488ea11 105 SMART SM00938 4 97 2.1E-42 T 23-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 TON_0154 53774793e415edcb8875539b5488ea11 105 PRINTS PR00340 P-II protein signature 2 17 1.2E-23 T 23-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 TON_0154 53774793e415edcb8875539b5488ea11 105 PRINTS PR00340 P-II protein signature 75 95 1.2E-23 T 23-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 TON_0154 53774793e415edcb8875539b5488ea11 105 PRINTS PR00340 P-II protein signature 44 67 1.2E-23 T 23-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 TON_0154 53774793e415edcb8875539b5488ea11 105 SUPERFAMILY SSF54913 1 104 1.3E-35 T 23-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta TON_0154 53774793e415edcb8875539b5488ea11 105 Pfam PF00543 Nitrogen regulatory protein P-II 4 97 1.2E-28 T 23-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 TON_0154 53774793e415edcb8875539b5488ea11 105 Gene3D G3DSA:3.30.70.120 1 105 2.5E-38 T 23-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal TON_0024 26b104f530f50f4d1721970f70a97d5f 105 PIRSF PIRSF029826 1 105 1.9E-41 T 23-10-2018 IPR025984 dCTP pyrophosphatase 1 GO:0009143|GO:0047429 KEGG: 00240+3.6.1.12|Reactome: R-HSA-499943 TON_0024 26b104f530f50f4d1721970f70a97d5f 105 Pfam PF12643 MazG-like family 30 104 1.4E-22 T 23-10-2018 IPR025984 dCTP pyrophosphatase 1 GO:0009143|GO:0047429 KEGG: 00240+3.6.1.12|Reactome: R-HSA-499943 TON_0024 26b104f530f50f4d1721970f70a97d5f 105 Gene3D G3DSA:1.10.287.1080 1 105 3.9E-35 T 23-10-2018 TON_0024 26b104f530f50f4d1721970f70a97d5f 105 SUPERFAMILY SSF101386 2 105 7.46E-33 T 23-10-2018 TON_1100 99d728518a5b4b9c65ef9a9375d7b826 299 Pfam PF08271 TFIIB zinc-binding 6 47 2.1E-19 T 23-10-2018 IPR013137 Zinc finger, TFIIB-type TON_1100 99d728518a5b4b9c65ef9a9375d7b826 299 ProSitePatterns PS00782 Transcription factor TFIIB repeat signature. 148 163 - T 23-10-2018 IPR023486 Transcription factor TFIIB, conserved site Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-674695|Reactome: R-HSA-6807505|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-76042 TON_1100 99d728518a5b4b9c65ef9a9375d7b826 299 SUPERFAMILY SSF47954 113 200 6.81E-28 T 23-10-2018 IPR036915 Cyclin-like superfamily TON_1100 99d728518a5b4b9c65ef9a9375d7b826 299 Gene3D G3DSA:1.10.472.10 207 299 8.0E-29 T 23-10-2018 TON_1100 99d728518a5b4b9c65ef9a9375d7b826 299 SUPERFAMILY SSF47954 206 298 4.35E-30 T 23-10-2018 IPR036915 Cyclin-like superfamily TON_1100 99d728518a5b4b9c65ef9a9375d7b826 299 Hamap MF_00383 Transcription initiation factor IIB [tfb]. 1 297 44.674 T 23-10-2018 IPR023484 Transcription initiation factor TFIIB, archaea TON_1100 99d728518a5b4b9c65ef9a9375d7b826 299 SUPERFAMILY SSF57783 4 50 2.1E-17 T 23-10-2018 TON_1100 99d728518a5b4b9c65ef9a9375d7b826 299 Pfam PF00382 Transcription factor TFIIB repeat 117 186 1.3E-20 T 23-10-2018 IPR013150 Transcription factor TFIIB, cyclin-like domain GO:0017025 TON_1100 99d728518a5b4b9c65ef9a9375d7b826 299 Pfam PF00382 Transcription factor TFIIB repeat 212 282 9.2E-23 T 23-10-2018 IPR013150 Transcription factor TFIIB, cyclin-like domain GO:0017025 TON_1100 99d728518a5b4b9c65ef9a9375d7b826 299 Gene3D G3DSA:1.10.472.170 6 197 4.0E-68 T 23-10-2018 TON_1100 99d728518a5b4b9c65ef9a9375d7b826 299 SMART SM00385 210 291 3.9E-13 T 23-10-2018 IPR013763 Cyclin-like TON_1100 99d728518a5b4b9c65ef9a9375d7b826 299 SMART SM00385 114 195 1.8E-12 T 23-10-2018 IPR013763 Cyclin-like TON_1100 99d728518a5b4b9c65ef9a9375d7b826 299 PRINTS PR00685 Transcription initiation factor IIB signature 19 39 1.3E-62 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 TON_1100 99d728518a5b4b9c65ef9a9375d7b826 299 PRINTS PR00685 Transcription initiation factor IIB signature 211 229 1.3E-62 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 TON_1100 99d728518a5b4b9c65ef9a9375d7b826 299 PRINTS PR00685 Transcription initiation factor IIB signature 182 197 1.3E-62 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 TON_1100 99d728518a5b4b9c65ef9a9375d7b826 299 PRINTS PR00685 Transcription initiation factor IIB signature 54 75 1.3E-62 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 TON_1100 99d728518a5b4b9c65ef9a9375d7b826 299 PRINTS PR00685 Transcription initiation factor IIB signature 41 54 1.3E-62 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 TON_1100 99d728518a5b4b9c65ef9a9375d7b826 299 PRINTS PR00685 Transcription initiation factor IIB signature 156 175 1.3E-62 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 TON_1100 99d728518a5b4b9c65ef9a9375d7b826 299 PRINTS PR00685 Transcription initiation factor IIB signature 245 261 1.3E-62 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 TON_1100 99d728518a5b4b9c65ef9a9375d7b826 299 PRINTS PR00685 Transcription initiation factor IIB signature 277 291 1.3E-62 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 TON_1438 4180e04e366be9b5317791edc087bf39 151 ProDom PD006194 REGULATORY ASPARTATE CARBAMOYLTRANSFERASE CHAIN METAL-BINDING ZINC PYRIMIDINE BIOSYNTHESIS SUBUNIT TRANSFERASE 6 97 2.0E-34 T 23-10-2018 IPR020545 Aspartate carbamoyltransferase regulatory subunit, N-terminal TON_1438 4180e04e366be9b5317791edc087bf39 151 SUPERFAMILY SSF57825 100 148 1.83E-16 T 23-10-2018 IPR036792 Aspartate carbamoyltransferase regulatory subunit, C-terminal domain superfamily TON_1438 4180e04e366be9b5317791edc087bf39 151 SUPERFAMILY SSF54893 3 98 2.09E-32 T 23-10-2018 IPR036793 Aspartate carbamoyltransferase regulatory subunit, N-terminal domain superfamily TON_1438 4180e04e366be9b5317791edc087bf39 151 TIGRFAM TIGR00240 ATCase_reg: aspartate carbamoyltransferase, regulatory subunit 2 149 2.0E-61 T 23-10-2018 IPR002801 Aspartate transcarbamylase regulatory subunit GO:0006207|GO:0009347 TON_1438 4180e04e366be9b5317791edc087bf39 151 Gene3D G3DSA:2.30.30.20 98 151 1.2E-22 T 23-10-2018 TON_1438 4180e04e366be9b5317791edc087bf39 151 Pfam PF01948 Aspartate carbamoyltransferase regulatory chain, allosteric domain 4 96 5.7E-33 T 23-10-2018 IPR020545 Aspartate carbamoyltransferase regulatory subunit, N-terminal TON_1438 4180e04e366be9b5317791edc087bf39 151 Pfam PF02748 Aspartate carbamoyltransferase regulatory chain, metal binding domain 100 147 4.3E-20 T 23-10-2018 IPR020542 Aspartate carbamoyltransferase regulatory subunit, C-terminal TON_1438 4180e04e366be9b5317791edc087bf39 151 Gene3D G3DSA:3.30.70.140 1 97 3.7E-37 T 23-10-2018 IPR036793 Aspartate carbamoyltransferase regulatory subunit, N-terminal domain superfamily TON_1438 4180e04e366be9b5317791edc087bf39 151 Hamap MF_00002 Aspartate carbamoyltransferase regulatory chain [pyrI]. 1 149 34.321 T 23-10-2018 IPR002801 Aspartate transcarbamylase regulatory subunit GO:0006207|GO:0009347 TON_0408 78a4249c88b0449aec414825e1e2a977 206 SUPERFAMILY SSF160975 23 199 3.27E-91 T 23-10-2018 TON_0408 78a4249c88b0449aec414825e1e2a977 206 Pfam PF04919 Protein of unknown function (DUF655) 23 198 2.1E-68 T 23-10-2018 IPR007003 Protein of unknown function DUF655 TON_0408 78a4249c88b0449aec414825e1e2a977 206 Gene3D G3DSA:1.10.150.280 93 190 2.0E-42 T 23-10-2018 TON_0408 78a4249c88b0449aec414825e1e2a977 206 Gene3D G3DSA:2.40.50.140 23 92 3.3E-22 T 23-10-2018 TON_0752 894ecfd39f9178ed34141f89e9687065 428 SUPERFAMILY SSF50447 213 315 7.9E-29 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily TON_0752 894ecfd39f9178ed34141f89e9687065 428 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 59 74 - T 23-10-2018 IPR031157 Tr-type G domain, conserved site TON_0752 894ecfd39f9178ed34141f89e9687065 428 Gene3D G3DSA:2.40.30.10 320 425 1.9E-41 T 23-10-2018 TON_0752 894ecfd39f9178ed34141f89e9687065 428 Pfam PF03144 Elongation factor Tu domain 2 235 306 7.7E-18 T 23-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 TON_0752 894ecfd39f9178ed34141f89e9687065 428 Gene3D G3DSA:2.40.30.10 216 310 3.2E-41 T 23-10-2018 TON_0752 894ecfd39f9178ed34141f89e9687065 428 Hamap MF_00118_A Elongation factor Tu [tuf]. 2 427 61.465 T 23-10-2018 IPR004539 Translation elongation factor EF1A, eukaryotic/archaeal GO:0003746|GO:0005525|GO:0005737|GO:0006414 Reactome: R-HSA-156842 TON_0752 894ecfd39f9178ed34141f89e9687065 428 Gene3D G3DSA:3.40.50.300 1 212 4.9E-87 T 23-10-2018 TON_0752 894ecfd39f9178ed34141f89e9687065 428 PRINTS PR00315 GTP-binding elongation factor signature 66 74 1.4E-24 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TON_0752 894ecfd39f9178ed34141f89e9687065 428 PRINTS PR00315 GTP-binding elongation factor signature 102 113 1.4E-24 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TON_0752 894ecfd39f9178ed34141f89e9687065 428 PRINTS PR00315 GTP-binding elongation factor signature 86 96 1.4E-24 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TON_0752 894ecfd39f9178ed34141f89e9687065 428 PRINTS PR00315 GTP-binding elongation factor signature 9 22 1.4E-24 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TON_0752 894ecfd39f9178ed34141f89e9687065 428 PRINTS PR00315 GTP-binding elongation factor signature 139 148 1.4E-24 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TON_0752 894ecfd39f9178ed34141f89e9687065 428 SUPERFAMILY SSF50465 321 424 7.91E-40 T 23-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal TON_0752 894ecfd39f9178ed34141f89e9687065 428 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 8 190 1.3E-17 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 TON_0752 894ecfd39f9178ed34141f89e9687065 428 Pfam PF03143 Elongation factor Tu C-terminal domain 317 424 7.7E-38 T 23-10-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal TON_0752 894ecfd39f9178ed34141f89e9687065 428 TIGRFAM TIGR00483 EF-1_alpha: translation elongation factor EF-1, subunit alpha 1 427 1.5E-213 T 23-10-2018 IPR004539 Translation elongation factor EF1A, eukaryotic/archaeal GO:0003746|GO:0005525|GO:0005737|GO:0006414 Reactome: R-HSA-156842 TON_0752 894ecfd39f9178ed34141f89e9687065 428 Pfam PF00009 Elongation factor Tu GTP binding domain 5 209 1.2E-58 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TON_0752 894ecfd39f9178ed34141f89e9687065 428 SUPERFAMILY SSF52540 3 236 2.8E-76 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_0291 59aeeecfd7eaa3a33a2921af68f67cab 481 Gene3D G3DSA:1.10.287.70 395 481 2.0E-14 T 23-10-2018 TON_0291 59aeeecfd7eaa3a33a2921af68f67cab 481 Pfam PF07885 Ion channel 403 480 3.0E-13 T 23-10-2018 IPR013099 Potassium channel domain TON_0291 59aeeecfd7eaa3a33a2921af68f67cab 481 SUPERFAMILY SSF81324 394 480 1.44E-16 T 23-10-2018 TON_0159 c922f067da488ec0d3a8b1ca65b82ea3 301 Pfam PF02653 Branched-chain amino acid transport system / permease component 5 283 3.0E-46 T 23-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TON_0579 9ed2ce1c08065cfee66e3c69341c72be 733 Gene3D G3DSA:3.40.50.620 5 316 1.3E-142 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TON_0579 9ed2ce1c08065cfee66e3c69341c72be 733 Pfam PF08264 Anticodon-binding domain of tRNA 430 523 6.3E-13 T 23-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 TON_0579 9ed2ce1c08065cfee66e3c69341c72be 733 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 11 22 - T 23-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 TON_0579 9ed2ce1c08065cfee66e3c69341c72be 733 Gene3D G3DSA:1.10.730.10 341 581 1.6E-104 T 23-10-2018 TON_0579 9ed2ce1c08065cfee66e3c69341c72be 733 Gene3D G3DSA:2.40.50.140 627 733 1.0E-43 T 23-10-2018 TON_0579 9ed2ce1c08065cfee66e3c69341c72be 733 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 5 549 2.0E-177 T 23-10-2018 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 TON_0579 9ed2ce1c08065cfee66e3c69341c72be 733 Pfam PF01588 Putative tRNA binding domain 639 730 1.6E-31 T 23-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 TON_0579 9ed2ce1c08065cfee66e3c69341c72be 733 TIGRFAM TIGR00399 metG_C_term: methionine--tRNA ligase, beta subunit 612 733 5.3E-38 T 23-10-2018 IPR004495 Methionyl-tRNA synthetase, beta subunit, C-terminal GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 TON_0579 9ed2ce1c08065cfee66e3c69341c72be 733 PRINTS PR01041 Methionyl-tRNA synthetase signature 39 53 2.9E-32 T 23-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 TON_0579 9ed2ce1c08065cfee66e3c69341c72be 733 PRINTS PR01041 Methionyl-tRNA synthetase signature 87 98 2.9E-32 T 23-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 TON_0579 9ed2ce1c08065cfee66e3c69341c72be 733 PRINTS PR01041 Methionyl-tRNA synthetase signature 252 263 2.9E-32 T 23-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 TON_0579 9ed2ce1c08065cfee66e3c69341c72be 733 PRINTS PR01041 Methionyl-tRNA synthetase signature 396 407 2.9E-32 T 23-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 TON_0579 9ed2ce1c08065cfee66e3c69341c72be 733 PRINTS PR01041 Methionyl-tRNA synthetase signature 6 19 2.9E-32 T 23-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 TON_0579 9ed2ce1c08065cfee66e3c69341c72be 733 PRINTS PR01041 Methionyl-tRNA synthetase signature 294 309 2.9E-32 T 23-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 TON_0579 9ed2ce1c08065cfee66e3c69341c72be 733 Hamap MF_00098 Methionine--tRNA ligase [metG]. 2 560 42.724 T 23-10-2018 IPR023458 Methionine-tRNA ligase, type 1 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 TON_0579 9ed2ce1c08065cfee66e3c69341c72be 733 SUPERFAMILY SSF57770 139 173 1.16E-11 T 23-10-2018 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 TON_0579 9ed2ce1c08065cfee66e3c69341c72be 733 SUPERFAMILY SSF50249 632 732 3.92E-37 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold TON_0579 9ed2ce1c08065cfee66e3c69341c72be 733 Pfam PF09334 tRNA synthetases class I (M) 4 408 2.7E-159 T 23-10-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 TON_0579 9ed2ce1c08065cfee66e3c69341c72be 733 SUPERFAMILY SSF52374 3 395 6.82E-105 T 23-10-2018 TON_0579 9ed2ce1c08065cfee66e3c69341c72be 733 Gene3D G3DSA:1.10.730.10 398 548 1.6E-104 T 23-10-2018 TON_0579 9ed2ce1c08065cfee66e3c69341c72be 733 SUPERFAMILY SSF47323 398 563 1.76E-46 T 23-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 TON_0579 9ed2ce1c08065cfee66e3c69341c72be 733 Gene3D G3DSA:2.170.220.10 98 252 1.3E-142 T 23-10-2018 TON_1659 d65feb774ead7b94025094d4768f86f3 480 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 204 479 21.249 T 23-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 TON_1659 d65feb774ead7b94025094d4768f86f3 480 Gene3D G3DSA:3.40.50.10260 9 204 2.2E-42 T 23-10-2018 IPR036652 YjeF N-terminal domain superfamily MetaCyc: PWY-6938 TON_1659 d65feb774ead7b94025094d4768f86f3 480 Pfam PF01256 Carbohydrate kinase 227 471 3.1E-52 T 23-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 TON_1659 d65feb774ead7b94025094d4768f86f3 480 ProSitePatterns PS01050 YjeF C-terminal domain signature 2. 415 425 - T 23-10-2018 IPR017953 Carbohydrate kinase, predicted, conserved site TON_1659 d65feb774ead7b94025094d4768f86f3 480 PIRSF PIRSF017184 2 479 3.4E-97 T 23-10-2018 IPR030677 Bifunctional NAD(P)H-hydrate repair enzyme Nnr GO:0052855 MetaCyc: PWY-6938 TON_1659 d65feb774ead7b94025094d4768f86f3 480 Gene3D G3DSA:3.40.1190.20 210 477 9.8E-75 T 23-10-2018 IPR029056 Ribokinase-like TON_1659 d65feb774ead7b94025094d4768f86f3 480 Hamap MF_01966 NAD(P)H-hydrate epimerase [nnrE]. 1 198 18.713 T 23-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 TON_1659 d65feb774ead7b94025094d4768f86f3 480 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 211 475 1.1E-72 T 23-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 TON_1659 d65feb774ead7b94025094d4768f86f3 480 SUPERFAMILY SSF53613 212 474 6.35E-60 T 23-10-2018 IPR029056 Ribokinase-like TON_1659 d65feb774ead7b94025094d4768f86f3 480 SUPERFAMILY SSF64153 4 226 7.85E-49 T 23-10-2018 IPR036652 YjeF N-terminal domain superfamily MetaCyc: PWY-6938 TON_1659 d65feb774ead7b94025094d4768f86f3 480 TIGRFAM TIGR00197 yjeF_nterm: YjeF family N-terminal domain 8 183 1.8E-42 T 23-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 TON_1659 d65feb774ead7b94025094d4768f86f3 480 Pfam PF03853 YjeF-related protein N-terminus 22 182 1.8E-33 T 23-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 TON_0096 f1c69f8dbe2c8c7b8c9f3b9efe5ed183 334 TIGRFAM TIGR00451 unchar_dom_2: uncharacterized domain 2 240 320 2.8E-10 T 23-10-2018 IPR004521 Uncharacterised domain CHP00451 GO:0003723 TON_0096 f1c69f8dbe2c8c7b8c9f3b9efe5ed183 334 Hamap MF_01081 Probable tRNA pseudouridine synthase B [truB]. 40 325 51.503 T 23-10-2018 IPR026326 Probable tRNA pseudouridine synthase B, archaeal GO:0006396 TON_0096 f1c69f8dbe2c8c7b8c9f3b9efe5ed183 334 Gene3D G3DSA:2.30.130.70 23 332 1.2E-148 T 23-10-2018 TON_0096 f1c69f8dbe2c8c7b8c9f3b9efe5ed183 334 Pfam PF01472 PUA domain 251 323 1.2E-20 T 23-10-2018 IPR002478 PUA domain GO:0003723 TON_0096 f1c69f8dbe2c8c7b8c9f3b9efe5ed183 334 Pfam PF08068 DKCLD (NUC011) domain 15 63 1.3E-18 T 23-10-2018 IPR012960 Dyskerin-like Reactome: R-HSA-171319|Reactome: R-HSA-6790901 TON_0096 f1c69f8dbe2c8c7b8c9f3b9efe5ed183 334 SMART SM01136 4 63 1.6E-25 T 23-10-2018 IPR012960 Dyskerin-like Reactome: R-HSA-171319|Reactome: R-HSA-6790901 TON_0096 f1c69f8dbe2c8c7b8c9f3b9efe5ed183 334 SUPERFAMILY SSF55120 21 247 3.74E-77 T 23-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 TON_0096 f1c69f8dbe2c8c7b8c9f3b9efe5ed183 334 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 120 180 1.3E-6 T 23-10-2018 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 TON_0096 f1c69f8dbe2c8c7b8c9f3b9efe5ed183 334 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 67 119 9.6E-16 T 23-10-2018 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 TON_0096 f1c69f8dbe2c8c7b8c9f3b9efe5ed183 334 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 181 247 1.0E-23 T 23-10-2018 IPR032819 tRNA pseudouridylate synthase B, C-terminal Reactome: R-HSA-171319|Reactome: R-HSA-6790901 TON_0096 f1c69f8dbe2c8c7b8c9f3b9efe5ed183 334 SMART SM00359 251 325 5.9E-21 T 23-10-2018 IPR002478 PUA domain GO:0003723 TON_0096 f1c69f8dbe2c8c7b8c9f3b9efe5ed183 334 Gene3D G3DSA:3.30.2350.10 40 243 1.2E-148 T 23-10-2018 TON_0096 f1c69f8dbe2c8c7b8c9f3b9efe5ed183 334 SUPERFAMILY SSF88697 249 332 3.54E-23 T 23-10-2018 IPR015947 PUA-like superfamily TON_0096 f1c69f8dbe2c8c7b8c9f3b9efe5ed183 334 TIGRFAM TIGR00425 CBF5: putative rRNA pseudouridine synthase 17 334 3.5E-136 T 23-10-2018 IPR004802 tRNA pseudouridine synthase B family GO:0006396 Reactome: R-HSA-171319|Reactome: R-HSA-6790901 TON_0549 7e635933f9ab458dd59c6aee8ad65bd1 289 SUPERFAMILY SSF103481 48 143 1.7E-13 T 23-10-2018 TON_0549 7e635933f9ab458dd59c6aee8ad65bd1 289 Pfam PF00892 EamA-like transporter family 153 288 2.7E-24 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TON_0549 7e635933f9ab458dd59c6aee8ad65bd1 289 Pfam PF00892 EamA-like transporter family 6 141 1.4E-23 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TON_0549 7e635933f9ab458dd59c6aee8ad65bd1 289 SUPERFAMILY SSF103481 187 287 3.53E-11 T 23-10-2018 TON_0275 15f39122be8568dfb3bbce1b02e30715 205 Gene3D G3DSA:3.30.70.3270 30 160 1.6E-20 T 23-10-2018 TON_0275 15f39122be8568dfb3bbce1b02e30715 205 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 52 63 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TON_0275 15f39122be8568dfb3bbce1b02e30715 205 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 87 98 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TON_0275 15f39122be8568dfb3bbce1b02e30715 205 Pfam PF12838 4Fe-4S dicluster domain 52 101 1.2E-13 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TON_0275 15f39122be8568dfb3bbce1b02e30715 205 SUPERFAMILY SSF54862 22 110 1.47E-22 T 23-10-2018 TON_0072 7ed5297b8d9da8aef297ea233e303a30 208 SUPERFAMILY SSF54821 86 186 1.7E-26 T 23-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0072 7ed5297b8d9da8aef297ea233e303a30 208 Pfam PF00189 Ribosomal protein S3, C-terminal domain 99 182 4.6E-24 T 23-10-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0072 7ed5297b8d9da8aef297ea233e303a30 208 TIGRFAM TIGR01008 uS3_euk_arch: ribosomal protein uS3 3 197 1.2E-94 T 23-10-2018 IPR005703 Ribosomal protein S3, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0072 7ed5297b8d9da8aef297ea233e303a30 208 Gene3D G3DSA:3.30.300.20 1 86 4.8E-30 T 23-10-2018 IPR015946 K homology domain-like, alpha/beta TON_0072 7ed5297b8d9da8aef297ea233e303a30 208 SUPERFAMILY SSF54814 7 93 7.59E-26 T 23-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 TON_0072 7ed5297b8d9da8aef297ea233e303a30 208 SMART SM00322 38 104 1.7E-7 T 23-10-2018 IPR004087 K Homology domain GO:0003676 TON_0072 7ed5297b8d9da8aef297ea233e303a30 208 Hamap MF_01309_A 30S ribosomal protein S3 [rpsC]. 2 197 42.737 T 23-10-2018 IPR027488 Ribosomal protein S3, archaeal GO:0003735|GO:0006412|GO:0015935 TON_0072 7ed5297b8d9da8aef297ea233e303a30 208 Gene3D G3DSA:3.30.1140.32 87 208 2.0E-42 T 23-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0072 7ed5297b8d9da8aef297ea233e303a30 208 Pfam PF07650 KH domain 17 88 3.0E-15 T 23-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0123 41158afd972420df6174111a9c353dc1 448 SUPERFAMILY SSF52540 97 297 3.5E-48 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_0123 41158afd972420df6174111a9c353dc1 448 Pfam PF02978 Signal peptide binding domain 327 425 4.2E-35 T 23-10-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 TON_0123 41158afd972420df6174111a9c353dc1 448 Pfam PF02881 SRP54-type protein, helical bundle domain 6 83 3.1E-21 T 23-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 TON_0123 41158afd972420df6174111a9c353dc1 448 SMART SM00963 2 87 7.5E-25 T 23-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 TON_0123 41158afd972420df6174111a9c353dc1 448 SUPERFAMILY SSF47364 1 94 4.71E-24 T 23-10-2018 IPR036225 SRP/SRP receptor, N-terminal Reactome: R-HSA-1799339 TON_0123 41158afd972420df6174111a9c353dc1 448 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 268 281 - T 23-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 TON_0123 41158afd972420df6174111a9c353dc1 448 Gene3D G3DSA:1.20.120.140 6 305 6.6E-125 T 23-10-2018 TON_0123 41158afd972420df6174111a9c353dc1 448 Gene3D G3DSA:3.40.50.300 91 284 6.6E-125 T 23-10-2018 TON_0123 41158afd972420df6174111a9c353dc1 448 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 6 438 38.565 T 23-10-2018 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 TON_0123 41158afd972420df6174111a9c353dc1 448 Pfam PF00448 SRP54-type protein, GTPase domain 100 295 3.0E-77 T 23-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 TON_0123 41158afd972420df6174111a9c353dc1 448 SMART SM00962 100 295 6.9E-102 T 23-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 TON_0123 41158afd972420df6174111a9c353dc1 448 Gene3D G3DSA:1.10.260.30 310 443 1.6E-51 T 23-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 TON_0123 41158afd972420df6174111a9c353dc1 448 SUPERFAMILY SSF47446 297 429 4.58E-44 T 23-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 TON_0123 41158afd972420df6174111a9c353dc1 448 SMART SM00382 99 273 2.0E-5 T 23-10-2018 IPR003593 AAA+ ATPase domain TON_0078 0029ce327194162a97eea9a4a43cfe0d 243 Pfam PF00900 Ribosomal family S4e 96 173 1.1E-21 T 23-10-2018 IPR013845 Ribosomal protein S4e, central region Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0078 0029ce327194162a97eea9a4a43cfe0d 243 Gene3D G3DSA:2.30.30.30 179 243 5.4E-18 T 23-10-2018 IPR014722 Ribosomal protein L2, domain 2 TON_0078 0029ce327194162a97eea9a4a43cfe0d 243 ProDom PD002667 RIBOSOMAL RIBONUCLEOPROTEIN RNA-BINDING 40S S4 S4 S4E 30S ISOFORM X 88 182 8.0E-42 T 23-10-2018 IPR013845 Ribosomal protein S4e, central region Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0078 0029ce327194162a97eea9a4a43cfe0d 243 Pfam PF08071 RS4NT (NUC023) domain 4 39 2.8E-16 T 23-10-2018 IPR013843 Ribosomal protein S4e, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0078 0029ce327194162a97eea9a4a43cfe0d 243 SUPERFAMILY SSF55174 52 96 1.7E-7 T 23-10-2018 TON_0078 0029ce327194162a97eea9a4a43cfe0d 243 SMART SM00363 44 107 1.2E-9 T 23-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0078 0029ce327194162a97eea9a4a43cfe0d 243 PIRSF PIRSF002116 2 243 1.9E-99 T 23-10-2018 IPR000876 Ribosomal protein S4e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0078 0029ce327194162a97eea9a4a43cfe0d 243 Hamap MF_00485 30S ribosomal protein S4e [rps4e]. 8 242 42.627 T 23-10-2018 IPR000876 Ribosomal protein S4e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0078 0029ce327194162a97eea9a4a43cfe0d 243 Pfam PF01479 S4 domain 45 91 3.4E-13 T 23-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0078 0029ce327194162a97eea9a4a43cfe0d 243 Gene3D G3DSA:2.40.50.740 123 177 2.0E-15 T 23-10-2018 IPR038237 Ribosomal protein S4e, central domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0078 0029ce327194162a97eea9a4a43cfe0d 243 ProSitePatterns PS00528 Ribosomal protein S4e signature. 9 23 - T 23-10-2018 IPR018199 Ribosomal protein S4e, N-terminal, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0078 0029ce327194162a97eea9a4a43cfe0d 243 Gene3D G3DSA:3.10.290.40 1 118 1.0E-49 T 23-10-2018 TON_0879 dffd11603032a6339e12a7a460f58e1d 205 SUPERFAMILY SSF53850 1 201 1.18E-63 T 23-10-2018 TON_0879 dffd11603032a6339e12a7a460f58e1d 205 Gene3D G3DSA:3.40.190.10 3 193 1.1E-67 T 23-10-2018 TON_0879 dffd11603032a6339e12a7a460f58e1d 205 Hamap MF_01018 ATP phosphoribosyltransferase [hisG]. 1 202 50.175 T 23-10-2018 IPR024893 ATP phosphoribosyltransferase HisG, short form GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17 TON_0879 dffd11603032a6339e12a7a460f58e1d 205 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 1 177 5.2E-63 T 23-10-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 TON_0879 dffd11603032a6339e12a7a460f58e1d 205 Gene3D G3DSA:3.40.190.10 86 170 1.1E-67 T 23-10-2018 TON_0879 dffd11603032a6339e12a7a460f58e1d 205 Pfam PF01634 ATP phosphoribosyltransferase 46 198 1.8E-51 T 23-10-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 TON_0879 dffd11603032a6339e12a7a460f58e1d 205 ProSitePatterns PS01316 ATP phosphoribosyltransferase signature. 137 158 - T 23-10-2018 IPR018198 ATP phosphoribosyltransferase, conserved site GO:0003879 KEGG: 00340+2.4.2.17 TON_1099 36f6c9d771a00185bc89fb89d1713b5e 341 SUPERFAMILY SSF47807 221 339 3.74E-34 T 23-10-2018 IPR036279 5'-3' exonuclease, C-terminal domain superfamily TON_1099 36f6c9d771a00185bc89fb89d1713b5e 341 Gene3D G3DSA:1.10.150.20 221 281 3.3E-21 T 23-10-2018 TON_1099 36f6c9d771a00185bc89fb89d1713b5e 341 TIGRFAM TIGR03674 fen_arch: flap structure-specific endonuclease 1 338 6.7E-158 T 23-10-2018 IPR019973 Flap structure-specific endonuclease, archaea GO:0016788 TON_1099 36f6c9d771a00185bc89fb89d1713b5e 341 ProSitePatterns PS00841 XPG protein signature 1. 73 87 - T 23-10-2018 IPR019974 XPG conserved site GO:0016788 TON_1099 36f6c9d771a00185bc89fb89d1713b5e 341 SMART SM00485 1 101 2.4E-50 T 23-10-2018 IPR006085 XPG N-terminal GO:0004518|GO:0006281 TON_1099 36f6c9d771a00185bc89fb89d1713b5e 341 SMART SM00484 140 221 5.9E-38 T 23-10-2018 IPR006086 XPG-I domain GO:0004518 TON_1099 36f6c9d771a00185bc89fb89d1713b5e 341 SMART SM00279 223 257 1.0E-11 T 23-10-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 TON_1099 36f6c9d771a00185bc89fb89d1713b5e 341 Pfam PF00752 XPG N-terminal domain 12 101 5.4E-22 T 23-10-2018 IPR006085 XPG N-terminal GO:0004518|GO:0006281 TON_1099 36f6c9d771a00185bc89fb89d1713b5e 341 Hamap MF_00614 Flap endonuclease 1 [fen]. 1 339 148.832 T 23-10-2018 IPR023426 Flap endonuclease 1 GO:0016788 Reactome: R-HSA-110362|Reactome: R-HSA-162594|Reactome: R-HSA-174437|Reactome: R-HSA-5651801|Reactome: R-HSA-5685939|Reactome: R-HSA-69166 TON_1099 36f6c9d771a00185bc89fb89d1713b5e 341 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 21 35 7.7E-33 T 23-10-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 TON_1099 36f6c9d771a00185bc89fb89d1713b5e 341 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 139 156 7.7E-33 T 23-10-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 TON_1099 36f6c9d771a00185bc89fb89d1713b5e 341 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 226 241 7.7E-33 T 23-10-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 TON_1099 36f6c9d771a00185bc89fb89d1713b5e 341 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 75 94 7.7E-33 T 23-10-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 TON_1099 36f6c9d771a00185bc89fb89d1713b5e 341 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 160 180 7.7E-33 T 23-10-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 TON_1099 36f6c9d771a00185bc89fb89d1713b5e 341 SUPERFAMILY SSF88723 7 236 9.16E-66 T 23-10-2018 IPR029060 PIN-like domain superfamily TON_1099 36f6c9d771a00185bc89fb89d1713b5e 341 Pfam PF00867 XPG I-region 141 236 1.3E-28 T 23-10-2018 IPR006086 XPG-I domain GO:0004518 TON_1099 36f6c9d771a00185bc89fb89d1713b5e 341 Gene3D G3DSA:3.40.50.1010 1 220 2.2E-87 T 23-10-2018 TON_1857 699b01549fcebc0b6ad48efcc504a97e 391 Pfam PF13692 Glycosyl transferases group 1 221 358 8.0E-23 T 23-10-2018 TON_1857 699b01549fcebc0b6ad48efcc504a97e 391 Pfam PF13439 Glycosyltransferase Family 4 21 188 1.6E-12 T 23-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 TON_1857 699b01549fcebc0b6ad48efcc504a97e 391 Gene3D G3DSA:3.40.50.2000 21 387 4.1E-50 T 23-10-2018 TON_1857 699b01549fcebc0b6ad48efcc504a97e 391 Gene3D G3DSA:3.40.50.2000 185 377 4.1E-50 T 23-10-2018 TON_1857 699b01549fcebc0b6ad48efcc504a97e 391 SUPERFAMILY SSF53756 19 390 4.32E-52 T 23-10-2018 TON_1800 0a9d48a02e23f1ea73bbacc88f9e4cfc 360 Pfam PF13394 4Fe-4S single cluster domain 30 120 7.3E-6 T 23-10-2018 TON_1800 0a9d48a02e23f1ea73bbacc88f9e4cfc 360 Gene3D G3DSA:3.20.20.70 23 294 4.0E-19 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TON_1800 0a9d48a02e23f1ea73bbacc88f9e4cfc 360 SUPERFAMILY SSF102114 26 208 9.94E-26 T 23-10-2018 TON_1800 0a9d48a02e23f1ea73bbacc88f9e4cfc 360 Pfam PF04055 Radical SAM superfamily 31 184 4.9E-14 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TON_0075 ddaa0b2fd992b1ab3f891c0396d112ce 111 Gene3D G3DSA:2.40.50.1000 1 111 1.2E-38 T 23-10-2018 TON_0075 ddaa0b2fd992b1ab3f891c0396d112ce 111 Pfam PF00366 Ribosomal protein S17 35 102 7.6E-26 T 23-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TON_0075 ddaa0b2fd992b1ab3f891c0396d112ce 111 Hamap MF_01345_A 30S ribosomal protein S17 [rpsQ]. 2 106 33.42 T 23-10-2018 IPR019978 Ribosomal protein S17, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 TON_0075 ddaa0b2fd992b1ab3f891c0396d112ce 111 PRINTS PR00973 Ribosomal protein S17 family signature 82 92 8.9E-11 T 23-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TON_0075 ddaa0b2fd992b1ab3f891c0396d112ce 111 PRINTS PR00973 Ribosomal protein S17 family signature 49 72 8.9E-11 T 23-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TON_0075 ddaa0b2fd992b1ab3f891c0396d112ce 111 PRINTS PR00973 Ribosomal protein S17 family signature 92 99 8.9E-11 T 23-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TON_0075 ddaa0b2fd992b1ab3f891c0396d112ce 111 TIGRFAM TIGR03630 uS17_arch: ribosomal protein uS17 4 104 1.5E-47 T 23-10-2018 IPR028333 Ribosomal protein S17, archaeal/eukaryotic Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0075 ddaa0b2fd992b1ab3f891c0396d112ce 111 ProSitePatterns PS00056 Ribosomal protein S17 signature. 82 94 - T 23-10-2018 IPR019979 Ribosomal protein S17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0075 ddaa0b2fd992b1ab3f891c0396d112ce 111 SUPERFAMILY SSF50249 29 108 1.24E-27 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold TON_0075 ddaa0b2fd992b1ab3f891c0396d112ce 111 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 31 102 8.0E-32 T 23-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TON_0173 ce98ff04b693bc695d69d917c2322274 149 Pfam PF08905 Domain of unknown function (DUF1850) 42 121 7.5E-13 T 23-10-2018 IPR015001 Protein of unknown function DUF1850 TON_1689 7e50a0e7ed2e7c8c12b9f116e7054a16 370 Gene3D G3DSA:3.50.50.60 1 367 1.9E-56 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TON_1689 7e50a0e7ed2e7c8c12b9f116e7054a16 370 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 244 259 1.4E-11 T 23-10-2018 TON_1689 7e50a0e7ed2e7c8c12b9f116e7054a16 370 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 1.4E-11 T 23-10-2018 TON_1689 7e50a0e7ed2e7c8c12b9f116e7054a16 370 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 134 149 1.4E-11 T 23-10-2018 TON_1689 7e50a0e7ed2e7c8c12b9f116e7054a16 370 Pfam PF01494 FAD binding domain 3 169 2.0E-13 T 23-10-2018 IPR002938 FAD-binding domain GO:0071949 TON_1689 7e50a0e7ed2e7c8c12b9f116e7054a16 370 TIGRFAM TIGR02032 GG-red-SF: geranylgeranyl reductase family 3 272 7.8E-50 T 23-10-2018 IPR011777 Geranylgeranyl reductase family GO:0016628|GO:0055114 TON_1689 7e50a0e7ed2e7c8c12b9f116e7054a16 370 SUPERFAMILY SSF51905 3 283 5.37E-32 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TON_0671 e964a8114793633f00d7aaf6c63bfa7f 455 SUPERFAMILY SSF111283 2 450 2.35E-98 T 23-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 TON_0671 e964a8114793633f00d7aaf6c63bfa7f 455 PIRSF PIRSF004919 1 455 2.1E-153 T 23-10-2018 IPR025502 TldD TON_0671 e964a8114793633f00d7aaf6c63bfa7f 455 Pfam PF01523 Putative modulator of DNA gyrase 19 310 1.1E-45 T 23-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 TON_0671 e964a8114793633f00d7aaf6c63bfa7f 455 Gene3D G3DSA:3.30.2290.10 1 216 2.8E-18 T 23-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal TON_1306 6ba8978254c3b52f34e45313df379b93 177 Pfam PF01381 Helix-turn-helix 95 142 3.2E-6 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TON_1306 6ba8978254c3b52f34e45313df379b93 177 TIGRFAM TIGR00270 TIGR00270: TIGR00270 family protein 8 171 6.6E-23 T 23-10-2018 IPR004451 Conserved hypothetical protein CHP00270 TON_1306 6ba8978254c3b52f34e45313df379b93 177 Gene3D G3DSA:1.10.260.40 79 177 5.9E-11 T 23-10-2018 TON_1306 6ba8978254c3b52f34e45313df379b93 177 SUPERFAMILY SSF47413 80 146 2.51E-7 T 23-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TON_1306 6ba8978254c3b52f34e45313df379b93 177 SMART SM00530 90 145 2.7E-5 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TON_0118 50edeaa41188fa0c5e0e61dcb0c5e6c5 150 Pfam PF01037 Lrp/AsnC ligand binding domain 68 137 2.0E-15 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain TON_0118 50edeaa41188fa0c5e0e61dcb0c5e6c5 150 Gene3D G3DSA:3.30.70.920 54 147 6.7E-22 T 23-10-2018 TON_0118 50edeaa41188fa0c5e0e61dcb0c5e6c5 150 Pfam PF13412 Winged helix-turn-helix DNA-binding 3 49 2.7E-18 T 23-10-2018 TON_0118 50edeaa41188fa0c5e0e61dcb0c5e6c5 150 SMART SM00344 2 108 2.7E-43 T 23-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 TON_0118 50edeaa41188fa0c5e0e61dcb0c5e6c5 150 SUPERFAMILY SSF54909 62 145 1.07E-16 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel TON_0118 50edeaa41188fa0c5e0e61dcb0c5e6c5 150 Gene3D G3DSA:1.10.10.10 2 52 3.3E-21 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TON_0118 50edeaa41188fa0c5e0e61dcb0c5e6c5 150 SUPERFAMILY SSF46785 2 62 1.1E-17 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TON_0118 50edeaa41188fa0c5e0e61dcb0c5e6c5 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 2 18 1.1E-13 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TON_0118 50edeaa41188fa0c5e0e61dcb0c5e6c5 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 18 29 1.1E-13 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TON_0118 50edeaa41188fa0c5e0e61dcb0c5e6c5 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 29 48 1.1E-13 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TON_1511 01a801667ab37e393a1ec8abb4120cf9 419 Gene3D G3DSA:3.40.50.150 73 410 5.9E-119 T 23-10-2018 TON_1511 01a801667ab37e393a1ec8abb4120cf9 419 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 347 378 - T 23-10-2018 IPR030390 RNA methyltransferase TrmA, active site TON_1511 01a801667ab37e393a1ec8abb4120cf9 419 Gene3D G3DSA:2.40.50.140 2 71 1.6E-12 T 23-10-2018 TON_1511 01a801667ab37e393a1ec8abb4120cf9 419 Gene3D G3DSA:3.40.1350.30 112 257 5.9E-119 T 23-10-2018 TON_1511 01a801667ab37e393a1ec8abb4120cf9 419 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 236 415 1.7E-22 T 23-10-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 TON_1511 01a801667ab37e393a1ec8abb4120cf9 419 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 398 408 - T 23-10-2018 IPR030391 RNA methyltransferase TrmA, conserved site TON_1511 01a801667ab37e393a1ec8abb4120cf9 419 SUPERFAMILY SSF50249 4 57 1.43E-7 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold TON_1511 01a801667ab37e393a1ec8abb4120cf9 419 SUPERFAMILY SSF53335 60 413 7.72E-69 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TON_1511 01a801667ab37e393a1ec8abb4120cf9 419 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 8 408 6.1E-84 T 23-10-2018 TON_0213 86ebce56154a36274e58f631557b9fdb 446 Gene3D G3DSA:3.90.1150.10 70 442 1.5E-152 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TON_0213 86ebce56154a36274e58f631557b9fdb 446 SUPERFAMILY SSF53383 3 445 2.18E-103 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TON_0213 86ebce56154a36274e58f631557b9fdb 446 Hamap MF_00712 Probable glycine dehydrogenase (decarboxylating) subunit 1 [gcvPA]. 3 445 48.071 T 23-10-2018 IPR023010 Probable glycine dehydrogenase (decarboxylating) subunit 1 GO:0004375|GO:0009116 KEGG: 00260+1.4.4.2 TON_0213 86ebce56154a36274e58f631557b9fdb 446 Gene3D G3DSA:3.40.640.10 81 349 1.5E-152 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TON_0213 86ebce56154a36274e58f631557b9fdb 446 Pfam PF02347 Glycine cleavage system P-protein 4 442 4.6E-124 T 23-10-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 TON_0213 86ebce56154a36274e58f631557b9fdb 446 PIRSF PIRSF006815 3 446 4.7E-162 T 23-10-2018 IPR023010 Probable glycine dehydrogenase (decarboxylating) subunit 1 GO:0004375|GO:0009116 KEGG: 00260+1.4.4.2 TON_0745 c25e3b16c3df885c28fb22e340be1253 292 SMART SM00849 15 200 1.8E-13 T 23-10-2018 IPR001279 Metallo-beta-lactamase TON_0745 c25e3b16c3df885c28fb22e340be1253 292 SUPERFAMILY SSF56281 15 276 3.79E-30 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TON_0745 c25e3b16c3df885c28fb22e340be1253 292 Pfam PF00753 Metallo-beta-lactamase superfamily 16 161 1.1E-8 T 23-10-2018 IPR001279 Metallo-beta-lactamase TON_0745 c25e3b16c3df885c28fb22e340be1253 292 Gene3D G3DSA:3.60.15.10 16 216 2.9E-24 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TON_1113 c03da1bf06f7e34fd04f28c4aadeaad1 163 Gene3D G3DSA:2.60.40.790 4 161 9.6E-32 T 23-10-2018 IPR008978 HSP20-like chaperone TON_1113 c03da1bf06f7e34fd04f28c4aadeaad1 163 Pfam PF00011 Hsp20/alpha crystallin family 59 154 7.3E-19 T 23-10-2018 IPR002068 Alpha crystallin/Hsp20 domain TON_1113 c03da1bf06f7e34fd04f28c4aadeaad1 163 SUPERFAMILY SSF49764 44 154 8.97E-32 T 23-10-2018 IPR008978 HSP20-like chaperone TON_0673 37843611c30222353848a2ba84927892 331 Gene3D G3DSA:3.40.50.150 143 331 1.6E-54 T 23-10-2018 TON_0673 37843611c30222353848a2ba84927892 331 Gene3D G3DSA:3.30.300.110 59 142 5.8E-28 T 23-10-2018 TON_0673 37843611c30222353848a2ba84927892 331 SUPERFAMILY SSF53335 72 329 3.29E-70 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TON_0673 37843611c30222353848a2ba84927892 331 Gene3D G3DSA:3.30.70.2580 2 58 1.9E-6 T 23-10-2018 TON_0673 37843611c30222353848a2ba84927892 331 Pfam PF02475 Met-10+ like-protein 82 277 1.8E-68 T 23-10-2018 IPR030382 SAM-dependent methyltransferase TRM5/TYW2-type Reactome: R-HSA-6782861 TON_0677 e5523d58cfebc8b09d9c3e824bf892e1 884 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 14 565 1.1E-143 T 23-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 TON_0677 e5523d58cfebc8b09d9c3e824bf892e1 884 TIGRFAM TIGR00422 valS: valine--tRNA ligase 3 862 2.1E-274 T 23-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 TON_0677 e5523d58cfebc8b09d9c3e824bf892e1 884 Hamap MF_02005 Valine--tRNA ligase [valS]. 2 789 29.058 T 23-10-2018 IPR022874 Valine-tRNA ligase, type 2 GO:0004832 KEGG: 00970+6.1.1.9 TON_0677 e5523d58cfebc8b09d9c3e824bf892e1 884 SUPERFAMILY SSF52374 3 574 2.92E-130 T 23-10-2018 TON_0677 e5523d58cfebc8b09d9c3e824bf892e1 884 Gene3D G3DSA:3.40.50.620 22 530 9.5E-246 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TON_0677 e5523d58cfebc8b09d9c3e824bf892e1 884 PRINTS PR00986 Valyl-tRNA synthetase signature 481 499 1.9E-18 T 23-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 TON_0677 e5523d58cfebc8b09d9c3e824bf892e1 884 PRINTS PR00986 Valyl-tRNA synthetase signature 225 242 1.9E-18 T 23-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 TON_0677 e5523d58cfebc8b09d9c3e824bf892e1 884 PRINTS PR00986 Valyl-tRNA synthetase signature 450 471 1.9E-18 T 23-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 TON_0677 e5523d58cfebc8b09d9c3e824bf892e1 884 PRINTS PR00986 Valyl-tRNA synthetase signature 36 47 1.9E-18 T 23-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 TON_0677 e5523d58cfebc8b09d9c3e824bf892e1 884 PRINTS PR00986 Valyl-tRNA synthetase signature 343 356 1.9E-18 T 23-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 TON_0677 e5523d58cfebc8b09d9c3e824bf892e1 884 Pfam PF08264 Anticodon-binding domain of tRNA 610 758 1.3E-37 T 23-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 TON_0677 e5523d58cfebc8b09d9c3e824bf892e1 884 Gene3D G3DSA:1.10.730.10 2 746 9.5E-246 T 23-10-2018 TON_0677 e5523d58cfebc8b09d9c3e824bf892e1 884 SUPERFAMILY SSF47323 581 821 1.07E-60 T 23-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 TON_0677 e5523d58cfebc8b09d9c3e824bf892e1 884 Gene3D G3DSA:3.90.740.10 170 337 9.5E-246 T 23-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 TON_0677 e5523d58cfebc8b09d9c3e824bf892e1 884 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 43 54 - T 23-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 TON_0677 e5523d58cfebc8b09d9c3e824bf892e1 884 SUPERFAMILY SSF50677 187 335 1.57E-51 T 23-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 TON_0364 a8a7c165d520213c23367db33d328b83 284 Gene3D G3DSA:3.40.50.300 2 276 1.9E-71 T 23-10-2018 TON_0364 a8a7c165d520213c23367db33d328b83 284 SUPERFAMILY SSF52540 3 240 2.56E-59 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_0364 a8a7c165d520213c23367db33d328b83 284 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TON_0364 a8a7c165d520213c23367db33d328b83 284 SMART SM00382 30 227 4.4E-15 T 23-10-2018 IPR003593 AAA+ ATPase domain TON_0364 a8a7c165d520213c23367db33d328b83 284 Pfam PF00005 ABC transporter 21 178 1.2E-24 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TON_1309 6e40427aeccad32a9129ecc1e703085f 192 PRINTS PR00686 Transcription initiation factor TFIID signature 11 26 1.3E-43 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 TON_1309 6e40427aeccad32a9129ecc1e703085f 192 PRINTS PR00686 Transcription initiation factor TFIID signature 35 54 1.3E-43 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 TON_1309 6e40427aeccad32a9129ecc1e703085f 192 PRINTS PR00686 Transcription initiation factor TFIID signature 102 118 1.3E-43 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 TON_1309 6e40427aeccad32a9129ecc1e703085f 192 PRINTS PR00686 Transcription initiation factor TFIID signature 144 160 1.3E-43 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 TON_1309 6e40427aeccad32a9129ecc1e703085f 192 PRINTS PR00686 Transcription initiation factor TFIID signature 54 72 1.3E-43 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 TON_1309 6e40427aeccad32a9129ecc1e703085f 192 PRINTS PR00686 Transcription initiation factor TFIID signature 125 140 1.3E-43 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 TON_1309 6e40427aeccad32a9129ecc1e703085f 192 Pfam PF00352 Transcription factor TFIID (or TATA-binding protein, TBP) 9 89 1.9E-27 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 TON_1309 6e40427aeccad32a9129ecc1e703085f 192 Pfam PF00352 Transcription factor TFIID (or TATA-binding protein, TBP) 100 181 1.4E-28 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 TON_1309 6e40427aeccad32a9129ecc1e703085f 192 ProSitePatterns PS00351 Transcription factor TFIID repeat signature. 129 178 - T 23-10-2018 IPR030491 TATA-box binding protein, conserved site TON_1309 6e40427aeccad32a9129ecc1e703085f 192 Hamap MF_00408 TATA-box-binding protein [tbp]. 5 184 37.698 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 TON_1309 6e40427aeccad32a9129ecc1e703085f 192 SUPERFAMILY SSF55945 96 182 2.04E-30 T 23-10-2018 TON_1309 6e40427aeccad32a9129ecc1e703085f 192 SUPERFAMILY SSF55945 5 95 3.14E-29 T 23-10-2018 TON_1309 6e40427aeccad32a9129ecc1e703085f 192 Gene3D G3DSA:3.30.310.10 16 97 9.1E-33 T 23-10-2018 IPR012295 TBP domain superfamily TON_1309 6e40427aeccad32a9129ecc1e703085f 192 Gene3D G3DSA:3.30.310.10 98 182 3.7E-35 T 23-10-2018 IPR012295 TBP domain superfamily TON_1965 540a130efa795cb4c9db8c3591eef2e9 205 Gene3D G3DSA:3.30.700.20 9 192 3.3E-74 T 23-10-2018 IPR027485 AMMECR1, N-terminal TON_1965 540a130efa795cb4c9db8c3591eef2e9 205 Gene3D G3DSA:3.30.1490.150 117 190 3.3E-74 T 23-10-2018 TON_1965 540a130efa795cb4c9db8c3591eef2e9 205 Pfam PF01871 AMMECR1 13 190 1.7E-53 T 23-10-2018 IPR002733 AMMECR1 domain TON_1965 540a130efa795cb4c9db8c3591eef2e9 205 TIGRFAM TIGR00296 TIGR00296: uncharacterized protein, PH0010 family 4 197 1.5E-68 T 23-10-2018 IPR023473 AMMECR1 TON_1965 540a130efa795cb4c9db8c3591eef2e9 205 SUPERFAMILY SSF143447 4 202 6.15E-70 T 23-10-2018 IPR036071 AMMECR1 domain superfamily TON_1965 540a130efa795cb4c9db8c3591eef2e9 205 Hamap MF_00645 Protein . 5 188 42.003 T 23-10-2018 IPR023472 Uncharacterised protein family MJ0810 TON_1965 540a130efa795cb4c9db8c3591eef2e9 205 TIGRFAM TIGR04335 AmmeMemoSam_A: AmmeMemoRadiSam system protein A 11 190 7.0E-59 T 23-10-2018 IPR027623 AmmeMemoRadiSam system protein A TON_0902 892bf2160f828207e857b9ede05415bb 340 Gene3D G3DSA:2.30.30.100 293 340 1.4E-13 T 23-10-2018 TON_0902 892bf2160f828207e857b9ede05415bb 340 SUPERFAMILY SSF50037 293 338 1.19E-7 T 23-10-2018 IPR008988 Transcriptional repressor, C-terminal TON_0902 892bf2160f828207e857b9ede05415bb 340 Gene3D G3DSA:3.30.930.10 97 290 4.5E-62 T 23-10-2018 TON_0902 892bf2160f828207e857b9ede05415bb 340 Pfam PF02237 Biotin protein ligase C terminal domain 293 338 6.6E-10 T 23-10-2018 IPR003142 Biotin protein ligase, C-terminal GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 TON_0902 892bf2160f828207e857b9ede05415bb 340 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 108 338 7.8E-64 T 23-10-2018 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 TON_0902 892bf2160f828207e857b9ede05415bb 340 SUPERFAMILY SSF55681 100 287 9.32E-55 T 23-10-2018 TON_0902 892bf2160f828207e857b9ede05415bb 340 Pfam PF03099 Biotin/lipoate A/B protein ligase family 116 228 4.0E-18 T 23-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 TON_0204 3050a3c876662902047552f2deff7a8c 418 SUPERFAMILY SSF51905 6 326 5.32E-42 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TON_0204 3050a3c876662902047552f2deff7a8c 418 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 253 269 1.7E-25 T 23-10-2018 TON_0204 3050a3c876662902047552f2deff7a8c 418 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 116 134 1.7E-25 T 23-10-2018 TON_0204 3050a3c876662902047552f2deff7a8c 418 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 163 181 1.7E-25 T 23-10-2018 TON_0204 3050a3c876662902047552f2deff7a8c 418 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 11 30 1.7E-25 T 23-10-2018 TON_0204 3050a3c876662902047552f2deff7a8c 418 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 281 303 1.7E-25 T 23-10-2018 TON_0204 3050a3c876662902047552f2deff7a8c 418 Gene3D G3DSA:3.50.50.60 9 303 1.9E-52 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TON_0204 3050a3c876662902047552f2deff7a8c 418 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 9 301 3.4E-30 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TON_0204 3050a3c876662902047552f2deff7a8c 418 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 10 32 1.8E-19 T 23-10-2018 TON_0204 3050a3c876662902047552f2deff7a8c 418 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 296 303 1.8E-19 T 23-10-2018 TON_0204 3050a3c876662902047552f2deff7a8c 418 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 163 188 1.8E-19 T 23-10-2018 TON_0204 3050a3c876662902047552f2deff7a8c 418 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 254 268 1.8E-19 T 23-10-2018 TON_0204 3050a3c876662902047552f2deff7a8c 418 Gene3D G3DSA:3.50.50.60 128 261 1.9E-52 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TON_1198 4b7633aa695f62a07c72cfc2e5a74dc7 781 SUPERFAMILY SSF55052 178 260 4.71E-18 T 23-10-2018 IPR035891 CheY-binding domain of CheA TON_1198 4b7633aa695f62a07c72cfc2e5a74dc7 781 SUPERFAMILY SSF55874 461 642 1.1E-45 T 23-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TON_1198 4b7633aa695f62a07c72cfc2e5a74dc7 781 SUPERFAMILY SSF55052 270 353 2.62E-15 T 23-10-2018 IPR035891 CheY-binding domain of CheA TON_1198 4b7633aa695f62a07c72cfc2e5a74dc7 781 SMART SM00073 4 108 1.8E-23 T 23-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 TON_1198 4b7633aa695f62a07c72cfc2e5a74dc7 781 Gene3D G3DSA:3.30.565.10 458 644 4.5E-64 T 23-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TON_1198 4b7633aa695f62a07c72cfc2e5a74dc7 781 SUPERFAMILY SSF47226 4 132 6.28E-28 T 23-10-2018 IPR036641 HPT domain superfamily GO:0000160 TON_1198 4b7633aa695f62a07c72cfc2e5a74dc7 781 SMART SM00260 637 774 6.5E-40 T 23-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 TON_1198 4b7633aa695f62a07c72cfc2e5a74dc7 781 Gene3D G3DSA:1.20.120.160 1 149 6.4E-34 T 23-10-2018 IPR036641 HPT domain superfamily GO:0000160 TON_1198 4b7633aa695f62a07c72cfc2e5a74dc7 781 SUPERFAMILY SSF47384 398 458 1.1E-16 T 23-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TON_1198 4b7633aa695f62a07c72cfc2e5a74dc7 781 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 507 643 8.1E-19 T 23-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TON_1198 4b7633aa695f62a07c72cfc2e5a74dc7 781 Gene3D G3DSA:2.40.50.180 668 729 6.0E-38 T 23-10-2018 TON_1198 4b7633aa695f62a07c72cfc2e5a74dc7 781 PRINTS PR00344 Bacterial sensor protein C-terminal signature 547 561 2.8E-15 T 23-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TON_1198 4b7633aa695f62a07c72cfc2e5a74dc7 781 PRINTS PR00344 Bacterial sensor protein C-terminal signature 605 623 2.8E-15 T 23-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TON_1198 4b7633aa695f62a07c72cfc2e5a74dc7 781 PRINTS PR00344 Bacterial sensor protein C-terminal signature 589 599 2.8E-15 T 23-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TON_1198 4b7633aa695f62a07c72cfc2e5a74dc7 781 PRINTS PR00344 Bacterial sensor protein C-terminal signature 629 642 2.8E-15 T 23-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TON_1198 4b7633aa695f62a07c72cfc2e5a74dc7 781 Pfam PF01584 CheW-like domain 649 774 8.8E-24 T 23-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 TON_1198 4b7633aa695f62a07c72cfc2e5a74dc7 781 Gene3D G3DSA:2.30.30.40 645 769 6.0E-38 T 23-10-2018 TON_1198 4b7633aa695f62a07c72cfc2e5a74dc7 781 Pfam PF07194 P2 response regulator binding domain 180 260 5.1E-21 T 23-10-2018 IPR010808 Chemotaxis protein CheA, P2 response regulator-binding GO:0000155|GO:0000160|GO:0004673|GO:0006928 TON_1198 4b7633aa695f62a07c72cfc2e5a74dc7 781 Pfam PF07194 P2 response regulator binding domain 271 353 9.4E-16 T 23-10-2018 IPR010808 Chemotaxis protein CheA, P2 response regulator-binding GO:0000155|GO:0000160|GO:0004673|GO:0006928 TON_1198 4b7633aa695f62a07c72cfc2e5a74dc7 781 SUPERFAMILY SSF50341 644 774 3.66E-32 T 23-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 TON_1198 4b7633aa695f62a07c72cfc2e5a74dc7 781 Pfam PF01627 Hpt domain 6 104 9.6E-21 T 23-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 TON_1198 4b7633aa695f62a07c72cfc2e5a74dc7 781 Pfam PF02895 Signal transducing histidine kinase, homodimeric domain 398 457 3.0E-17 T 23-10-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 TON_1198 4b7633aa695f62a07c72cfc2e5a74dc7 781 SMART SM01231 397 457 2.9E-21 T 23-10-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 TON_1198 4b7633aa695f62a07c72cfc2e5a74dc7 781 Gene3D G3DSA:1.10.287.560 397 457 7.2E-20 T 23-10-2018 IPR037006 Histidine kinase CheA-like, homodimeric domain superfamily GO:0000155|GO:0006935 TON_1198 4b7633aa695f62a07c72cfc2e5a74dc7 781 SMART SM00387 502 645 1.8E-29 T 23-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TON_1198 4b7633aa695f62a07c72cfc2e5a74dc7 781 Gene3D G3DSA:3.30.70.1110 269 354 1.0E-9 T 23-10-2018 IPR037052 Chemotaxis protein CheA, P2 response regulator-binding domain superfamily TON_1198 4b7633aa695f62a07c72cfc2e5a74dc7 781 Gene3D G3DSA:3.30.70.1110 177 261 6.9E-16 T 23-10-2018 IPR037052 Chemotaxis protein CheA, P2 response regulator-binding domain superfamily TON_0402 d29185e5350dee643d4a06ae34a70ed0 630 SUPERFAMILY SSF89095 480 622 3.92E-29 T 23-10-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-like GO:0016884 TON_0402 d29185e5350dee643d4a06ae34a70ed0 630 SMART SM00845 482 622 1.2E-36 T 23-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 TON_0402 d29185e5350dee643d4a06ae34a70ed0 630 ProDom PD609240 SUBUNIT E AMIDOTRANSFERASE 6.3.5.- LIGASE GLUTAMYL-TRNAGLN GLU-ADT BIOSYNTHESIS TRANSFERASE B 280 404 3.0E-60 T 23-10-2018 TON_0402 d29185e5350dee643d4a06ae34a70ed0 630 Gene3D G3DSA:1.10.150.380 451 543 3.0E-24 T 23-10-2018 TON_0402 d29185e5350dee643d4a06ae34a70ed0 630 Gene3D G3DSA:3.30.1360.30 272 402 1.0E-52 T 23-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 TON_0402 d29185e5350dee643d4a06ae34a70ed0 630 Hamap MF_00588 Glutamyl-tRNA(Gln) amidotransferase subunit E [gatE]. 1 630 340.138 T 23-10-2018 IPR004414 Glutamyl-tRNA(Gln) amidotransferase subunit E GO:0016884 TON_0402 d29185e5350dee643d4a06ae34a70ed0 630 Gene3D G3DSA:1.10.10.410 564 623 4.6E-14 T 23-10-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal TON_0402 d29185e5350dee643d4a06ae34a70ed0 630 TIGRFAM TIGR00134 gatE_arch: glutamyl-tRNA(Gln) amidotransferase, subunit E 4 625 2.9E-240 T 23-10-2018 IPR004414 Glutamyl-tRNA(Gln) amidotransferase subunit E GO:0016884 TON_0402 d29185e5350dee643d4a06ae34a70ed0 630 Pfam PF02934 GatB/GatE catalytic domain 11 442 1.5E-66 T 23-10-2018 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 TON_0402 d29185e5350dee643d4a06ae34a70ed0 630 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 175 189 - T 23-10-2018 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 TON_0402 d29185e5350dee643d4a06ae34a70ed0 630 SUPERFAMILY SSF55261 276 402 1.31E-45 T 23-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 TON_0402 d29185e5350dee643d4a06ae34a70ed0 630 SUPERFAMILY SSF55931 3 451 4.64E-100 T 23-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 TON_0402 d29185e5350dee643d4a06ae34a70ed0 630 Pfam PF02938 GAD domain 297 388 9.7E-18 T 23-10-2018 IPR029351 GAD domain Reactome: R-HSA-379726 TON_0402 d29185e5350dee643d4a06ae34a70ed0 630 Pfam PF02637 GatB domain 483 622 4.2E-28 T 23-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 TON_0621 8f02e6a6c1d1783dfc543930073b790c 217 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 101 114 2.2E-5 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TON_0621 8f02e6a6c1d1783dfc543930073b790c 217 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 2 13 2.2E-5 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TON_0621 8f02e6a6c1d1783dfc543930073b790c 217 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 152 172 2.2E-5 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TON_0621 8f02e6a6c1d1783dfc543930073b790c 217 SUPERFAMILY SSF56784 1 215 1.47E-42 T 23-10-2018 IPR036412 HAD-like superfamily TON_0621 8f02e6a6c1d1783dfc543930073b790c 217 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 93 187 1.3E-7 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TON_0621 8f02e6a6c1d1783dfc543930073b790c 217 Gene3D G3DSA:1.10.150.240 17 86 1.4E-33 T 23-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 TON_0621 8f02e6a6c1d1783dfc543930073b790c 217 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 190 1.9E-25 T 23-10-2018 TON_0621 8f02e6a6c1d1783dfc543930073b790c 217 Gene3D G3DSA:3.40.50.1000 5 192 1.4E-33 T 23-10-2018 IPR023214 HAD superfamily TON_0621 8f02e6a6c1d1783dfc543930073b790c 217 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 105 184 3.3E-7 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TON_0990 c1c4fdfd9a74133e9c8258bee9f4942b 414 Gene3D G3DSA:3.40.50.1260 189 390 1.9E-136 T 23-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TON_0990 c1c4fdfd9a74133e9c8258bee9f4942b 414 SUPERFAMILY SSF53748 2 398 2.59E-114 T 23-10-2018 IPR036043 Phosphoglycerate kinase superfamily GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TON_0990 c1c4fdfd9a74133e9c8258bee9f4942b 414 Gene3D G3DSA:3.40.50.1260 10 397 1.9E-136 T 23-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TON_0990 c1c4fdfd9a74133e9c8258bee9f4942b 414 PRINTS PR00477 Phosphoglycerate kinase family signature 29 51 2.7E-66 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TON_0990 c1c4fdfd9a74133e9c8258bee9f4942b 414 PRINTS PR00477 Phosphoglycerate kinase family signature 8 24 2.7E-66 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TON_0990 c1c4fdfd9a74133e9c8258bee9f4942b 414 PRINTS PR00477 Phosphoglycerate kinase family signature 321 346 2.7E-66 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TON_0990 c1c4fdfd9a74133e9c8258bee9f4942b 414 PRINTS PR00477 Phosphoglycerate kinase family signature 170 192 2.7E-66 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TON_0990 c1c4fdfd9a74133e9c8258bee9f4942b 414 PRINTS PR00477 Phosphoglycerate kinase family signature 105 120 2.7E-66 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TON_0990 c1c4fdfd9a74133e9c8258bee9f4942b 414 PRINTS PR00477 Phosphoglycerate kinase family signature 376 393 2.7E-66 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TON_0990 c1c4fdfd9a74133e9c8258bee9f4942b 414 PRINTS PR00477 Phosphoglycerate kinase family signature 193 212 2.7E-66 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TON_0990 c1c4fdfd9a74133e9c8258bee9f4942b 414 PRINTS PR00477 Phosphoglycerate kinase family signature 354 365 2.7E-66 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TON_0990 c1c4fdfd9a74133e9c8258bee9f4942b 414 PRINTS PR00477 Phosphoglycerate kinase family signature 140 162 2.7E-66 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TON_0990 c1c4fdfd9a74133e9c8258bee9f4942b 414 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 4 400 34.393 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TON_0990 c1c4fdfd9a74133e9c8258bee9f4942b 414 Pfam PF00162 Phosphoglycerate kinase 5 389 4.5E-106 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TON_0990 c1c4fdfd9a74133e9c8258bee9f4942b 414 PIRSF PIRSF000724 1 407 1.7E-128 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TON_0990 c1c4fdfd9a74133e9c8258bee9f4942b 414 ProSitePatterns PS00111 Phosphoglycerate kinase signature. 13 23 - T 23-10-2018 IPR015911 Phosphoglycerate kinase, conserved site GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TON_0548 5f6d5052f3fc7eb3159f99b6bdc52ba8 190 Pfam PF01381 Helix-turn-helix 13 60 1.5E-14 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TON_0548 5f6d5052f3fc7eb3159f99b6bdc52ba8 190 Pfam PF00571 CBS domain 134 184 8.8E-7 T 23-10-2018 IPR000644 CBS domain TON_0548 5f6d5052f3fc7eb3159f99b6bdc52ba8 190 Pfam PF00571 CBS domain 70 121 7.4E-13 T 23-10-2018 IPR000644 CBS domain TON_0548 5f6d5052f3fc7eb3159f99b6bdc52ba8 190 SUPERFAMILY SSF54631 68 184 5.68E-27 T 23-10-2018 TON_0548 5f6d5052f3fc7eb3159f99b6bdc52ba8 190 SUPERFAMILY SSF47413 11 60 2.68E-14 T 23-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TON_0548 5f6d5052f3fc7eb3159f99b6bdc52ba8 190 Gene3D G3DSA:1.10.260.40 10 63 1.2E-16 T 23-10-2018 TON_0548 5f6d5052f3fc7eb3159f99b6bdc52ba8 190 PIRSF PIRSF037253 2 190 2.3E-81 T 23-10-2018 IPR017158 Transcription regulator, CBS domain-containing, predicted TON_0548 5f6d5052f3fc7eb3159f99b6bdc52ba8 190 SMART SM00530 12 68 3.7E-14 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TON_0548 5f6d5052f3fc7eb3159f99b6bdc52ba8 190 Gene3D G3DSA:3.10.580.10 64 186 1.9E-27 T 23-10-2018 TON_0548 5f6d5052f3fc7eb3159f99b6bdc52ba8 190 SMART SM00116 141 187 0.16 T 23-10-2018 IPR000644 CBS domain TON_0548 5f6d5052f3fc7eb3159f99b6bdc52ba8 190 SMART SM00116 77 124 3.6E-7 T 23-10-2018 IPR000644 CBS domain TON_0530 82ff447d9b6fc26a600011aa2ab99144 248 Gene3D G3DSA:3.40.50.300 1 244 3.9E-56 T 23-10-2018 TON_0530 82ff447d9b6fc26a600011aa2ab99144 248 SUPERFAMILY SSF52540 2 223 8.27E-48 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_0530 82ff447d9b6fc26a600011aa2ab99144 248 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TON_0530 82ff447d9b6fc26a600011aa2ab99144 248 Pfam PF00005 ABC transporter 17 167 8.6E-23 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TON_0530 82ff447d9b6fc26a600011aa2ab99144 248 SMART SM00382 26 226 3.0E-9 T 23-10-2018 IPR003593 AAA+ ATPase domain TON_0530 82ff447d9b6fc26a600011aa2ab99144 248 TIGRFAM TIGR01978 sufC: FeS assembly ATPase SufC 2 240 2.6E-82 T 23-10-2018 IPR010230 FeS cluster assembly SUF system, ATPase SufC GO:0005524 TON_1323 c263e00ec5817030376f9116c6fc26d6 172 TIGRFAM TIGR00286 TIGR00286: arginine decarboxylase, pyruvoyl-dependent 21 169 1.2E-38 T 23-10-2018 IPR002724 Pyruvoyl-dependent arginine decarboxylase GO:0006527|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 TON_1323 c263e00ec5817030376f9116c6fc26d6 172 Hamap MF_01404 Pyruvoyl-dependent arginine decarboxylase [pdaD]. 1 172 52.766 T 23-10-2018 IPR002724 Pyruvoyl-dependent arginine decarboxylase GO:0006527|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 TON_1323 c263e00ec5817030376f9116c6fc26d6 172 Gene3D G3DSA:3.50.20.10 59 171 7.8E-34 T 23-10-2018 IPR016105 Pyruvoyl-dependent histidine/arginine decarboxylase, 3-layer sandwich domain GO:0006520|GO:0016831 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 TON_1323 c263e00ec5817030376f9116c6fc26d6 172 ProDom PD010449 DECARBOXYLASE PYRUVOYL-DEPENDENT ARGININE SUBUNIT ALPHA CONTAINS: BETA PVLARGDC LYA DECARBOX 21 156 8.0E-69 T 23-10-2018 IPR002724 Pyruvoyl-dependent arginine decarboxylase GO:0006527|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 TON_1323 c263e00ec5817030376f9116c6fc26d6 172 PIRSF PIRSF005216 17 172 2.3E-46 T 23-10-2018 IPR002724 Pyruvoyl-dependent arginine decarboxylase GO:0006527|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 TON_1323 c263e00ec5817030376f9116c6fc26d6 172 SUPERFAMILY SSF56271 15 170 3.14E-45 T 23-10-2018 IPR016104 Pyruvoyl-dependent histidine/arginine decarboxylase GO:0006520|GO:0016831 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 TON_1323 c263e00ec5817030376f9116c6fc26d6 172 Gene3D G3DSA:3.30.60.30 12 58 2.8E-18 T 23-10-2018 TON_1323 c263e00ec5817030376f9116c6fc26d6 172 Pfam PF01862 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) 20 169 4.3E-40 T 23-10-2018 IPR002724 Pyruvoyl-dependent arginine decarboxylase GO:0006527|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 TON_1871 701f6b89779f592e778d36af87498851 237 TIGRFAM TIGR02495 NrdG2: anaerobic ribonucleoside-triphosphate reductase activating protein 3 192 1.6E-51 T 23-10-2018 IPR012840 Anaerobic ribonucleoside-triphosphate reductase activating protein TON_1871 701f6b89779f592e778d36af87498851 237 SUPERFAMILY SSF102114 26 169 5.36E-19 T 23-10-2018 TON_1871 701f6b89779f592e778d36af87498851 237 Gene3D G3DSA:3.20.20.70 3 173 4.4E-22 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TON_1871 701f6b89779f592e778d36af87498851 237 Pfam PF04055 Radical SAM superfamily 26 170 8.4E-16 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TON_1871 701f6b89779f592e778d36af87498851 237 Pfam PF13353 4Fe-4S single cluster domain 18 93 1.3E-8 T 23-10-2018 TON_1494 095285958267f7cc0b421d56c06e0cef 398 Gene3D G3DSA:3.30.70.1400 52 143 5.7E-90 T 23-10-2018 TON_1494 095285958267f7cc0b421d56c06e0cef 398 Gene3D G3DSA:2.40.30.110 309 383 8.6E-32 T 23-10-2018 TON_1494 095285958267f7cc0b421d56c06e0cef 398 SUPERFAMILY SSF103025 3 308 5.18E-94 T 23-10-2018 TON_1494 095285958267f7cc0b421d56c06e0cef 398 Gene3D G3DSA:3.30.1360.120 8 255 5.7E-90 T 23-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 TON_1494 095285958267f7cc0b421d56c06e0cef 398 PIRSF PIRSF006487 1 398 3.7E-106 T 23-10-2018 IPR028896 Aminomethyltransferase-like KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 TON_1494 095285958267f7cc0b421d56c06e0cef 398 Pfam PF01571 Aminomethyltransferase folate-binding domain 8 287 4.8E-96 T 23-10-2018 IPR006222 Aminomethyltransferase, folate-binding domain TON_1494 095285958267f7cc0b421d56c06e0cef 398 Hamap MF_00259 Aminomethyltransferase [gcvT]. 1 389 43.364 T 23-10-2018 IPR022903 Glycine cleavage system T protein, bacteria GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 TON_1494 095285958267f7cc0b421d56c06e0cef 398 TIGRFAM TIGR00528 gcvT: glycine cleavage system T protein 2 387 4.9E-96 T 23-10-2018 IPR006223 Glycine cleavage system T protein GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 TON_1494 095285958267f7cc0b421d56c06e0cef 398 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 293 383 1.9E-26 T 23-10-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 TON_1494 095285958267f7cc0b421d56c06e0cef 398 SUPERFAMILY SSF101790 300 392 5.23E-26 T 23-10-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal TON_1494 095285958267f7cc0b421d56c06e0cef 398 Gene3D G3DSA:4.10.1250.10 268 305 1.7E-9 T 23-10-2018 TON_0975 f7256d8c2919aac4ff00c83b428aa82a 253 Pfam PF02361 Cobalt transport protein 11 204 1.5E-26 T 23-10-2018 IPR003339 ABC/ECF transporter, transmembrane component TON_0635 79f3761882c54cdb23e00b6ece036d92 171 ProDom PD007457 TRANSFERASE ADENOSYLTRANSFERASE COBALAMIN ATP:COBIALAMIN ADENOSYLTRANSFERASE PDUO TYPE RELATED ACIDURIA YVQK 20 165 4.0E-51 T 23-10-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 TON_0635 79f3761882c54cdb23e00b6ece036d92 171 Pfam PF01923 Cobalamin adenosyltransferase 3 159 4.8E-50 T 23-10-2018 IPR016030 Cobalamin adenosyltransferase-like KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 TON_0635 79f3761882c54cdb23e00b6ece036d92 171 SUPERFAMILY SSF89028 2 165 1.1E-50 T 23-10-2018 IPR036451 Cobalamin adenosyltransferase-like superfamily KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 TON_0635 79f3761882c54cdb23e00b6ece036d92 171 Gene3D G3DSA:1.20.1200.10 24 171 2.4E-50 T 23-10-2018 IPR036451 Cobalamin adenosyltransferase-like superfamily KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 TON_0635 79f3761882c54cdb23e00b6ece036d92 171 TIGRFAM TIGR00636 PduO_Nterm: ATP:cob(I)alamin adenosyltransferase 4 169 7.3E-59 T 23-10-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 TON_0394 a0958d8e0dffdc2ed20b254bbd0a6507 267 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 1 227 30.883 T 23-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 TON_0394 a0958d8e0dffdc2ed20b254bbd0a6507 267 PIRSF PIRSF001430 1 243 3.1E-77 T 23-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 TON_0394 a0958d8e0dffdc2ed20b254bbd0a6507 267 Gene3D G3DSA:3.30.70.660 104 226 2.3E-24 T 23-10-2018 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0003723|GO:0009982 TON_0394 a0958d8e0dffdc2ed20b254bbd0a6507 267 SUPERFAMILY SSF55120 1 233 1.58E-64 T 23-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 TON_0394 a0958d8e0dffdc2ed20b254bbd0a6507 267 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 2 221 6.8E-50 T 23-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 TON_0394 a0958d8e0dffdc2ed20b254bbd0a6507 267 Gene3D G3DSA:3.30.70.580 1 103 5.2E-24 T 23-10-2018 TON_0394 a0958d8e0dffdc2ed20b254bbd0a6507 267 Pfam PF01416 tRNA pseudouridine synthase 129 228 4.8E-21 T 23-10-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 TON_1613 88b8b2aa00dc54051207e5392507e518 430 PRINTS PR00148 Enolase signature 162 175 2.2E-50 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TON_1613 88b8b2aa00dc54051207e5392507e518 430 PRINTS PR00148 Enolase signature 108 124 2.2E-50 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TON_1613 88b8b2aa00dc54051207e5392507e518 430 PRINTS PR00148 Enolase signature 366 383 2.2E-50 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TON_1613 88b8b2aa00dc54051207e5392507e518 430 PRINTS PR00148 Enolase signature 337 351 2.2E-50 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TON_1613 88b8b2aa00dc54051207e5392507e518 430 PRINTS PR00148 Enolase signature 39 53 2.2E-50 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TON_1613 88b8b2aa00dc54051207e5392507e518 430 PRINTS PR00148 Enolase signature 314 325 2.2E-50 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TON_1613 88b8b2aa00dc54051207e5392507e518 430 Gene3D G3DSA:3.20.20.120 129 428 4.6E-135 T 23-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily TON_1613 88b8b2aa00dc54051207e5392507e518 430 Pfam PF00113 Enolase, C-terminal TIM barrel domain 141 427 1.5E-132 T 23-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TON_1613 88b8b2aa00dc54051207e5392507e518 430 ProSitePatterns PS00164 Enolase signature. 337 350 - T 23-10-2018 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TON_1613 88b8b2aa00dc54051207e5392507e518 430 SUPERFAMILY SSF51604 139 429 6.81E-127 T 23-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily TON_1613 88b8b2aa00dc54051207e5392507e518 430 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 7 426 9.5E-200 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TON_1613 88b8b2aa00dc54051207e5392507e518 430 Gene3D G3DSA:3.30.390.10 2 128 2.1E-57 T 23-10-2018 IPR029017 Enolase-like, N-terminal TON_1613 88b8b2aa00dc54051207e5392507e518 430 SMART SM01192 140 428 2.7E-209 T 23-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TON_1613 88b8b2aa00dc54051207e5392507e518 430 PIRSF PIRSF001400 3 427 1.5E-197 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TON_1613 88b8b2aa00dc54051207e5392507e518 430 SUPERFAMILY SSF54826 6 140 2.36E-58 T 23-10-2018 TON_1613 88b8b2aa00dc54051207e5392507e518 430 Hamap MF_00318 Enolase [eno]. 5 414 46.13 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TON_1613 88b8b2aa00dc54051207e5392507e518 430 SMART SM01193 7 135 7.6E-97 T 23-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TON_1613 88b8b2aa00dc54051207e5392507e518 430 Pfam PF03952 Enolase, N-terminal domain 7 135 1.2E-60 T 23-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TON_0686 f682783113b53849ff4aa0bde4dbcb5e 181 Gene3D G3DSA:3.90.550.10 2 176 1.7E-29 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TON_0686 f682783113b53849ff4aa0bde4dbcb5e 181 SUPERFAMILY SSF53448 2 168 1.76E-19 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TON_0686 f682783113b53849ff4aa0bde4dbcb5e 181 Pfam PF12804 MobA-like NTP transferase domain 3 108 3.2E-15 T 23-10-2018 IPR025877 MobA-like NTP transferase TON_0863 8b764bcdac38f74418f2287b982b3e40 409 Gene3D G3DSA:3.40.50.360 260 406 2.5E-28 T 23-10-2018 IPR029039 Flavoprotein-like superfamily TON_0863 8b764bcdac38f74418f2287b982b3e40 409 PIRSF PIRSF005243 3 409 5.1E-111 T 23-10-2018 IPR016440 Rubredoxin-oxygen oxidoreductase GO:0009055|GO:0010181|GO:0016491|GO:0046872 TON_0863 8b764bcdac38f74418f2287b982b3e40 409 Gene3D G3DSA:3.60.15.10 1 258 2.6E-89 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TON_0863 8b764bcdac38f74418f2287b982b3e40 409 SUPERFAMILY SSF56281 3 254 2.23E-42 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TON_0863 8b764bcdac38f74418f2287b982b3e40 409 SUPERFAMILY SSF52218 262 408 1.22E-31 T 23-10-2018 IPR029039 Flavoprotein-like superfamily TON_0863 8b764bcdac38f74418f2287b982b3e40 409 SMART SM00849 39 209 4.9E-24 T 23-10-2018 IPR001279 Metallo-beta-lactamase TON_0881 cc1d08149827b35bf5edcd5ecc7de376 176 ProSitePatterns PS00955 Imidazoleglycerol-phosphate dehydratase signature 2. 141 153 - T 23-10-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 TON_0881 cc1d08149827b35bf5edcd5ecc7de376 176 Gene3D G3DSA:3.30.230.40 77 176 1.1E-32 T 23-10-2018 IPR038494 Imidazole glycerol phosphate dehydratase domain superfamily KEGG: 00340+4.2.1.19 TON_0881 cc1d08149827b35bf5edcd5ecc7de376 176 Pfam PF00475 Imidazoleglycerol-phosphate dehydratase 22 159 1.4E-37 T 23-10-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 TON_0881 cc1d08149827b35bf5edcd5ecc7de376 176 SUPERFAMILY SSF54211 75 163 2.28E-24 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TON_0881 cc1d08149827b35bf5edcd5ecc7de376 176 Gene3D G3DSA:3.30.230.40 1 74 2.7E-20 T 23-10-2018 IPR038494 Imidazole glycerol phosphate dehydratase domain superfamily KEGG: 00340+4.2.1.19 TON_0881 cc1d08149827b35bf5edcd5ecc7de376 176 SUPERFAMILY SSF54211 2 74 3.34E-16 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TON_0979 a24e06fc1c395d1871fb677e5a0f6518 846 Pfam PF00271 Helicase conserved C-terminal domain 419 536 3.8E-14 T 23-10-2018 IPR001650 Helicase, C-terminal TON_0979 a24e06fc1c395d1871fb677e5a0f6518 846 Gene3D G3DSA:3.40.50.300 200 402 1.2E-51 T 23-10-2018 TON_0979 a24e06fc1c395d1871fb677e5a0f6518 846 SMART SM00487 213 410 2.0E-31 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TON_0979 a24e06fc1c395d1871fb677e5a0f6518 846 Gene3D G3DSA:3.40.50.300 404 603 7.8E-30 T 23-10-2018 TON_0979 a24e06fc1c395d1871fb677e5a0f6518 846 SUPERFAMILY SSF52540 227 552 7.2E-51 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_0979 a24e06fc1c395d1871fb677e5a0f6518 846 Pfam PF00270 DEAD/DEAH box helicase 219 382 6.1E-25 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 TON_0979 a24e06fc1c395d1871fb677e5a0f6518 846 SMART SM00490 453 538 3.0E-20 T 23-10-2018 IPR001650 Helicase, C-terminal TON_0352 2c9f37d3464620a4cd4d3a83ddeb62c3 533 SUPERFAMILY SSF52540 3 265 6.33E-122 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_0352 2c9f37d3464620a4cd4d3a83ddeb62c3 533 Hamap MF_01227 CTP synthase [pyrG]. 2 530 53.255 T 23-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 TON_0352 2c9f37d3464620a4cd4d3a83ddeb62c3 533 Pfam PF06418 CTP synthase N-terminus 3 265 6.5E-128 T 23-10-2018 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 TON_0352 2c9f37d3464620a4cd4d3a83ddeb62c3 533 Gene3D G3DSA:3.40.50.300 1 283 3.8E-140 T 23-10-2018 TON_0352 2c9f37d3464620a4cd4d3a83ddeb62c3 533 Gene3D G3DSA:3.40.50.880 284 532 4.4E-108 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like TON_0352 2c9f37d3464620a4cd4d3a83ddeb62c3 533 Pfam PF00117 Glutamine amidotransferase class-I 300 525 1.1E-58 T 23-10-2018 IPR017926 Glutamine amidotransferase TON_0352 2c9f37d3464620a4cd4d3a83ddeb62c3 533 SUPERFAMILY SSF52317 288 528 3.21E-80 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like TON_0352 2c9f37d3464620a4cd4d3a83ddeb62c3 533 TIGRFAM TIGR00337 PyrG: CTP synthase 2 525 1.2E-253 T 23-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 TON_0282 71827e4f5ac6260cc011bc6d59f9fbdb 183 ProSitePatterns PS01081 TetR-type HTH domain signature. 19 50 - T 23-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site TON_0282 71827e4f5ac6260cc011bc6d59f9fbdb 183 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 28 51 7.3E-13 T 23-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TON_0282 71827e4f5ac6260cc011bc6d59f9fbdb 183 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 7 20 7.3E-13 T 23-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TON_0282 71827e4f5ac6260cc011bc6d59f9fbdb 183 Pfam PF00440 Bacterial regulatory proteins, tetR family 7 51 1.3E-20 T 23-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TON_0282 71827e4f5ac6260cc011bc6d59f9fbdb 183 SUPERFAMILY SSF46689 2 56 3.34E-19 T 23-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TON_0282 71827e4f5ac6260cc011bc6d59f9fbdb 183 Gene3D G3DSA:1.10.357.10 1 183 1.5E-30 T 23-10-2018 TON_0001 414a6a483105b4cd8b68f2805a3037a3 1308 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 1003 1027 4.1E-8 T 23-10-2018 IPR030934 Intein C-terminal splicing region TON_0001 414a6a483105b4cd8b68f2805a3037a3 1308 Gene3D G3DSA:1.10.287.690 447 494 3.8E-18 T 23-10-2018 TON_0001 414a6a483105b4cd8b68f2805a3037a3 1308 Pfam PF03104 DNA polymerase family B, exonuclease domain 130 278 2.9E-33 T 23-10-2018 IPR006133 DNA-directed DNA polymerase, family B, exonuclease domain KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TON_0001 414a6a483105b4cd8b68f2805a3037a3 1308 Pfam PF03104 DNA polymerase family B, exonuclease domain 22 129 1.2E-12 T 23-10-2018 IPR006133 DNA-directed DNA polymerase, family B, exonuclease domain KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TON_0001 414a6a483105b4cd8b68f2805a3037a3 1308 Gene3D G3DSA:3.30.420.10 131 347 2.0E-171 T 23-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 TON_0001 414a6a483105b4cd8b68f2805a3037a3 1308 SUPERFAMILY SSF51294 492 1027 2.75E-39 T 23-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TON_0001 414a6a483105b4cd8b68f2805a3037a3 1308 PRINTS PR00379 Intein signature 1021 1030 6.9E-25 T 23-10-2018 IPR006142 Intein GO:0016539 TON_0001 414a6a483105b4cd8b68f2805a3037a3 1308 PRINTS PR00379 Intein signature 890 905 6.9E-25 T 23-10-2018 IPR006142 Intein GO:0016539 TON_0001 414a6a483105b4cd8b68f2805a3037a3 1308 PRINTS PR00379 Intein signature 1001 1018 6.9E-25 T 23-10-2018 IPR006142 Intein GO:0016539 TON_0001 414a6a483105b4cd8b68f2805a3037a3 1308 PRINTS PR00379 Intein signature 576 589 6.9E-25 T 23-10-2018 IPR006142 Intein GO:0016539 TON_0001 414a6a483105b4cd8b68f2805a3037a3 1308 PRINTS PR00379 Intein signature 767 779 6.9E-25 T 23-10-2018 IPR006142 Intein GO:0016539 TON_0001 414a6a483105b4cd8b68f2805a3037a3 1308 PRINTS PR00379 Intein signature 863 875 6.9E-25 T 23-10-2018 IPR006142 Intein GO:0016539 TON_0001 414a6a483105b4cd8b68f2805a3037a3 1308 SMART SM00306 490 613 2.0E-28 T 23-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TON_0001 414a6a483105b4cd8b68f2805a3037a3 1308 Gene3D G3DSA:3.90.1600.20 378 444 7.8E-14 T 23-10-2018 TON_0001 414a6a483105b4cd8b68f2805a3037a3 1308 TIGRFAM TIGR00592 pol2: DNA polymerase (pol2) 2 494 4.6E-100 T 23-10-2018 TON_0001 414a6a483105b4cd8b68f2805a3037a3 1308 TIGRFAM TIGR00592 pol2: DNA polymerase (pol2) 1025 1281 1.0E-101 T 23-10-2018 TON_0001 414a6a483105b4cd8b68f2805a3037a3 1308 SUPERFAMILY SSF56672 1025 1294 5.56E-82 T 23-10-2018 TON_0001 414a6a483105b4cd8b68f2805a3037a3 1308 Gene3D G3DSA:3.30.1490.210 932 984 1.6E-224 T 23-10-2018 TON_0001 414a6a483105b4cd8b68f2805a3037a3 1308 Pfam PF14528 LAGLIDADG-like domain 863 921 1.0E-5 T 23-10-2018 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 TON_0001 414a6a483105b4cd8b68f2805a3037a3 1308 Gene3D G3DSA:1.10.132.60 1142 1308 5.6E-62 T 23-10-2018 TON_0001 414a6a483105b4cd8b68f2805a3037a3 1308 ProSitePatterns PS00116 DNA polymerase family B signature. 1073 1081 - T 23-10-2018 IPR017964 DNA-directed DNA polymerase, family B, conserved site GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TON_0001 414a6a483105b4cd8b68f2805a3037a3 1308 Gene3D G3DSA:2.170.16.10 505 1023 1.6E-224 T 23-10-2018 TON_0001 414a6a483105b4cd8b68f2805a3037a3 1308 Gene3D G3DSA:3.10.28.10 763 931 1.6E-224 T 23-10-2018 IPR027434 Homing endonuclease TON_0001 414a6a483105b4cd8b68f2805a3037a3 1308 SUPERFAMILY SSF53098 1 347 7.09E-88 T 23-10-2018 IPR012337 Ribonuclease H-like superfamily TON_0001 414a6a483105b4cd8b68f2805a3037a3 1308 SMART SM00486 133 593 1.8E-101 T 23-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TON_0001 414a6a483105b4cd8b68f2805a3037a3 1308 Pfam PF00136 DNA polymerase family B 1026 1282 3.7E-45 T 23-10-2018 IPR006134 DNA-directed DNA polymerase, family B, multifunctional domain GO:0000166|GO:0003677 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TON_0001 414a6a483105b4cd8b68f2805a3037a3 1308 Pfam PF00136 DNA polymerase family B 352 493 2.2E-29 T 23-10-2018 IPR006134 DNA-directed DNA polymerase, family B, multifunctional domain GO:0000166|GO:0003677 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TON_0001 414a6a483105b4cd8b68f2805a3037a3 1308 Gene3D G3DSA:3.30.342.10 3 366 2.0E-171 T 23-10-2018 TON_0001 414a6a483105b4cd8b68f2805a3037a3 1308 SMART SM00305 984 1032 1.0E-13 T 23-10-2018 IPR003586 Hint domain C-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TON_0001 414a6a483105b4cd8b68f2805a3037a3 1308 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 400 413 2.4E-6 T 23-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TON_0001 414a6a483105b4cd8b68f2805a3037a3 1308 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 483 495 2.4E-6 T 23-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TON_0001 414a6a483105b4cd8b68f2805a3037a3 1308 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 1071 1079 2.4E-6 T 23-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TON_0001 414a6a483105b4cd8b68f2805a3037a3 1308 Gene3D G3DSA:3.90.1600.10 1024 1141 6.0E-39 T 23-10-2018 IPR023211 DNA polymerase, palm domain superfamily KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TON_0001 414a6a483105b4cd8b68f2805a3037a3 1308 Pfam PF14890 Intein splicing domain 504 1026 9.9E-57 T 23-10-2018 TON_0001 414a6a483105b4cd8b68f2805a3037a3 1308 TIGRFAM TIGR01445 intein_Nterm: intein N-terminal splicing region 495 589 6.4E-12 T 23-10-2018 IPR006141 Intein N-terminal splicing region GO:0016539 Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TON_0001 414a6a483105b4cd8b68f2805a3037a3 1308 SUPERFAMILY SSF56672 349 493 3.23E-43 T 23-10-2018 TON_0001 414a6a483105b4cd8b68f2805a3037a3 1308 Gene3D G3DSA:1.10.10.1010 617 762 1.6E-224 T 23-10-2018 TON_0001 414a6a483105b4cd8b68f2805a3037a3 1308 SUPERFAMILY SSF55608 846 934 6.38E-17 T 23-10-2018 IPR027434 Homing endonuclease TON_1719 b0c166693aec00421f995e73f42c0c41 181 Gene3D G3DSA:3.10.580.10 104 178 9.4E-18 T 23-10-2018 TON_1719 b0c166693aec00421f995e73f42c0c41 181 SMART SM00116 129 177 2.1E-10 T 23-10-2018 IPR000644 CBS domain TON_1719 b0c166693aec00421f995e73f42c0c41 181 SMART SM00116 51 98 6.6E-6 T 23-10-2018 IPR000644 CBS domain TON_1719 b0c166693aec00421f995e73f42c0c41 181 SUPERFAMILY SSF54631 32 176 1.18E-31 T 23-10-2018 TON_1719 b0c166693aec00421f995e73f42c0c41 181 Gene3D G3DSA:3.10.580.10 7 98 7.5E-13 T 23-10-2018 TON_1719 b0c166693aec00421f995e73f42c0c41 181 Pfam PF00571 CBS domain 122 176 2.1E-15 T 23-10-2018 IPR000644 CBS domain TON_1719 b0c166693aec00421f995e73f42c0c41 181 Pfam PF00571 CBS domain 47 97 9.0E-12 T 23-10-2018 IPR000644 CBS domain TON_0200 1c64b6746d513989811c8537210dfd54 245 Gene3D G3DSA:3.20.20.190 3 234 4.4E-36 T 23-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 TON_0200 1c64b6746d513989811c8537210dfd54 245 SUPERFAMILY SSF51695 4 227 2.51E-30 T 23-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 TON_0200 1c64b6746d513989811c8537210dfd54 245 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 9 86 1.3E-13 T 23-10-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 TON_0405 9f66bf152f394f6ef17b1946467776ef 386 TIGRFAM TIGR01213 pseudo_Pus10arc: tRNA pseudouridine(54/55) synthase 8 386 7.7E-146 T 23-10-2018 IPR005912 tRNA pseudouridine synthase, Pus10 GO:0000049|GO:0001522|GO:0006400|GO:0009982 TON_0405 9f66bf152f394f6ef17b1946467776ef 386 Gene3D G3DSA:3.30.70.2510 162 275 3.2E-31 T 23-10-2018 TON_0405 9f66bf152f394f6ef17b1946467776ef 386 Pfam PF02926 THUMP domain 26 162 2.6E-10 T 23-10-2018 IPR004114 THUMP domain GO:0003723 TON_0405 9f66bf152f394f6ef17b1946467776ef 386 SUPERFAMILY SSF55120 271 383 4.68E-12 T 23-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 TON_0405 9f66bf152f394f6ef17b1946467776ef 386 Gene3D G3DSA:3.30.70.3190 276 384 8.9E-29 T 23-10-2018 TON_0405 9f66bf152f394f6ef17b1946467776ef 386 Hamap MF_01893 tRNA pseudouridine synthase Pus10 [pus10]. 7 385 51.321 T 23-10-2018 IPR005912 tRNA pseudouridine synthase, Pus10 GO:0000049|GO:0001522|GO:0006400|GO:0009982 TON_1169 9fceb50eba7672aca15418f712510c1e 236 Pfam PF13419 Haloacid dehalogenase-like hydrolase 63 201 1.5E-27 T 23-10-2018 TON_1169 9fceb50eba7672aca15418f712510c1e 236 Gene3D G3DSA:1.10.150.240 16 101 2.5E-61 T 23-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 TON_1169 9fceb50eba7672aca15418f712510c1e 236 TIGRFAM TIGR02253 CTE7: HAD hydrolase, TIGR02253 family 1 227 1.7E-56 T 23-10-2018 IPR011950 HAD-superfamily hydrolase, subfamily IA, CTE7 GO:0016787 Reactome: R-HSA-4085001 TON_1169 9fceb50eba7672aca15418f712510c1e 236 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 104 197 3.9E-12 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TON_1169 9fceb50eba7672aca15418f712510c1e 236 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 114 202 1.4E-8 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TON_1169 9fceb50eba7672aca15418f712510c1e 236 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 146 162 8.1E-12 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TON_1169 9fceb50eba7672aca15418f712510c1e 236 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 164 184 8.1E-12 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TON_1169 9fceb50eba7672aca15418f712510c1e 236 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 115 128 8.1E-12 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TON_1169 9fceb50eba7672aca15418f712510c1e 236 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 2 13 8.1E-12 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TON_1169 9fceb50eba7672aca15418f712510c1e 236 Gene3D G3DSA:3.40.50.1000 4 223 2.5E-61 T 23-10-2018 IPR023214 HAD superfamily TON_1169 9fceb50eba7672aca15418f712510c1e 236 SUPERFAMILY SSF56784 1 229 7.59E-48 T 23-10-2018 IPR036412 HAD-like superfamily TON_1418 1abf3e7e3e33248203e4f991955b072b 167 SUPERFAMILY SSF55729 15 156 1.96E-40 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase TON_1418 1abf3e7e3e33248203e4f991955b072b 167 Pfam PF00583 Acetyltransferase (GNAT) family 28 137 8.4E-29 T 23-10-2018 IPR000182 GNAT domain TON_1418 1abf3e7e3e33248203e4f991955b072b 167 Gene3D G3DSA:3.40.630.30 16 163 3.8E-49 T 23-10-2018 TON_1418 1abf3e7e3e33248203e4f991955b072b 167 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 27 156 5.4E-35 T 23-10-2018 IPR006464 N-acetyltransferase RimI/Ard1 GO:0006474|GO:0016407 TON_0882 69151d90064ea031a9c5745731c19836 195 Pfam PF00117 Glutamine amidotransferase class-I 35 192 8.1E-22 T 23-10-2018 IPR017926 Glutamine amidotransferase TON_0882 69151d90064ea031a9c5745731c19836 195 Hamap MF_00278 Imidazole glycerol phosphate synthase subunit HisH [hisH]. 1 195 33.673 T 23-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 TON_0882 69151d90064ea031a9c5745731c19836 195 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 2 194 1.1E-61 T 23-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 TON_0882 69151d90064ea031a9c5745731c19836 195 SUPERFAMILY SSF52317 1 194 1.26E-47 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like TON_0882 69151d90064ea031a9c5745731c19836 195 Gene3D G3DSA:3.40.50.880 1 195 2.6E-62 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like TON_0882 69151d90064ea031a9c5745731c19836 195 PIRSF PIRSF000495 1 195 7.8E-59 T 23-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 TON_0168 ba0bad6f8c1e27556f9f65d554b3d4c2 227 Pfam PF06026 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) 51 221 2.7E-65 T 23-10-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 TON_0168 ba0bad6f8c1e27556f9f65d554b3d4c2 227 SUPERFAMILY SSF100950 2 150 4.19E-46 T 23-10-2018 IPR037171 NagB/RpiA transferase-like TON_0168 ba0bad6f8c1e27556f9f65d554b3d4c2 227 Gene3D G3DSA:3.40.50.1360 5 221 2.2E-89 T 23-10-2018 TON_0168 ba0bad6f8c1e27556f9f65d554b3d4c2 227 Hamap MF_00170 Ribose-5-phosphate isomerase A [rpiA]. 1 225 36.583 T 23-10-2018 IPR020672 Ribose-5-phosphate isomerase, type A, subgroup GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 TON_0168 ba0bad6f8c1e27556f9f65d554b3d4c2 227 SUPERFAMILY SSF75445 131 207 8.76E-25 T 23-10-2018 TON_0168 ba0bad6f8c1e27556f9f65d554b3d4c2 227 TIGRFAM TIGR00021 rpiA: ribose 5-phosphate isomerase A 4 223 5.0E-82 T 23-10-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 TON_0168 ba0bad6f8c1e27556f9f65d554b3d4c2 227 Gene3D G3DSA:3.30.70.260 127 205 2.2E-89 T 23-10-2018 TON_0502 d6dabd42645feb6682cdc5448bde8331 429 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 324 413 1.3E-25 T 23-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 TON_0502 d6dabd42645feb6682cdc5448bde8331 429 PIRSF PIRSF500136 1 426 7.8E-147 T 23-10-2018 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 TON_0502 d6dabd42645feb6682cdc5448bde8331 429 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 12 192 3.6E-52 T 23-10-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 TON_0502 d6dabd42645feb6682cdc5448bde8331 429 SUPERFAMILY SSF52413 315 413 3.66E-25 T 23-10-2018 IPR036220 UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily Reactome: R-HSA-173599 TON_0502 d6dabd42645feb6682cdc5448bde8331 429 SUPERFAMILY SSF51735 13 202 1.14E-50 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TON_0502 d6dabd42645feb6682cdc5448bde8331 429 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 12 409 7.7E-128 T 23-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 TON_0502 d6dabd42645feb6682cdc5448bde8331 429 SMART SM00984 323 414 6.1E-34 T 23-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 TON_0502 d6dabd42645feb6682cdc5448bde8331 429 Gene3D G3DSA:3.40.50.720 12 207 3.2E-74 T 23-10-2018 TON_0502 d6dabd42645feb6682cdc5448bde8331 429 SUPERFAMILY SSF48179 210 300 5.44E-27 T 23-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 TON_0502 d6dabd42645feb6682cdc5448bde8331 429 Gene3D G3DSA:3.40.50.720 241 429 2.6E-69 T 23-10-2018 TON_0502 d6dabd42645feb6682cdc5448bde8331 429 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 210 296 4.4E-24 T 23-10-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 TON_0502 d6dabd42645feb6682cdc5448bde8331 429 PIRSF PIRSF000124 11 417 3.8E-82 T 23-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 TON_0508 17857e43c7275d014c4f610bb0c6940a 78 Pfam PF07441 SigmaK-factor processing regulatory protein BofA 10 77 1.4E-8 T 23-10-2018 IPR010001 SigmaK-factor processing regulatory BofA TON_0064 1232b527b7dc9363798cf0835e7b8665 380 Gene3D G3DSA:3.30.1490.70 70 241 3.2E-68 T 23-10-2018 TON_0064 1232b527b7dc9363798cf0835e7b8665 380 Gene3D G3DSA:3.30.70.3350 244 374 1.8E-38 T 23-10-2018 TON_0064 1232b527b7dc9363798cf0835e7b8665 380 Gene3D G3DSA:3.30.70.3360 314 362 1.8E-38 T 23-10-2018 TON_0064 1232b527b7dc9363798cf0835e7b8665 380 Gene3D G3DSA:2.20.25.320 7 67 1.1E-21 T 23-10-2018 TON_0064 1232b527b7dc9363798cf0835e7b8665 380 Pfam PF09414 RNA ligase 86 240 7.1E-19 T 23-10-2018 IPR021122 RNA ligase domain, REL/Rln2 TON_0064 1232b527b7dc9363798cf0835e7b8665 380 TIGRFAM TIGR01209 TIGR01209: RNA ligase, Pab1020 family 10 380 4.5E-146 T 23-10-2018 IPR001072 RNA ligase, Pab1020 family TON_0064 1232b527b7dc9363798cf0835e7b8665 380 SUPERFAMILY SSF56091 63 259 1.6E-37 T 23-10-2018 TON_0064 1232b527b7dc9363798cf0835e7b8665 380 Gene3D G3DSA:3.30.470.30 96 197 3.2E-68 T 23-10-2018 TON_0064 1232b527b7dc9363798cf0835e7b8665 380 PRINTS PR01048 Hypothetical protein Y414 family signature 260 278 4.3E-53 T 23-10-2018 IPR001072 RNA ligase, Pab1020 family TON_0064 1232b527b7dc9363798cf0835e7b8665 380 PRINTS PR01048 Hypothetical protein Y414 family signature 355 375 4.3E-53 T 23-10-2018 IPR001072 RNA ligase, Pab1020 family TON_0064 1232b527b7dc9363798cf0835e7b8665 380 PRINTS PR01048 Hypothetical protein Y414 family signature 87 100 4.3E-53 T 23-10-2018 IPR001072 RNA ligase, Pab1020 family TON_0064 1232b527b7dc9363798cf0835e7b8665 380 PRINTS PR01048 Hypothetical protein Y414 family signature 291 305 4.3E-53 T 23-10-2018 IPR001072 RNA ligase, Pab1020 family TON_0064 1232b527b7dc9363798cf0835e7b8665 380 PRINTS PR01048 Hypothetical protein Y414 family signature 64 82 4.3E-53 T 23-10-2018 IPR001072 RNA ligase, Pab1020 family TON_0064 1232b527b7dc9363798cf0835e7b8665 380 PRINTS PR01048 Hypothetical protein Y414 family signature 219 232 4.3E-53 T 23-10-2018 IPR001072 RNA ligase, Pab1020 family TON_0064 1232b527b7dc9363798cf0835e7b8665 380 PRINTS PR01048 Hypothetical protein Y414 family signature 164 185 4.3E-53 T 23-10-2018 IPR001072 RNA ligase, Pab1020 family TON_0064 1232b527b7dc9363798cf0835e7b8665 380 PRINTS PR01048 Hypothetical protein Y414 family signature 108 123 4.3E-53 T 23-10-2018 IPR001072 RNA ligase, Pab1020 family TON_0064 1232b527b7dc9363798cf0835e7b8665 380 PRINTS PR01048 Hypothetical protein Y414 family signature 138 153 4.3E-53 T 23-10-2018 IPR001072 RNA ligase, Pab1020 family TON_0064 1232b527b7dc9363798cf0835e7b8665 380 PRINTS PR01048 Hypothetical protein Y414 family signature 42 56 4.3E-53 T 23-10-2018 IPR001072 RNA ligase, Pab1020 family TON_0652 5772dc7d05ffd594c7a9c0dd63fb1af9 357 Gene3D G3DSA:2.30.30.870 1 130 1.8E-38 T 23-10-2018 IPR038069 Pelota/DOM34, N-terminal domain TON_0652 5772dc7d05ffd594c7a9c0dd63fb1af9 357 Pfam PF03463 eRF1 domain 1 9 127 2.7E-28 T 23-10-2018 IPR005140 eRF1 domain 1/Pelota-like TON_0652 5772dc7d05ffd594c7a9c0dd63fb1af9 357 TIGRFAM TIGR00111 pelota: mRNA surveillance protein pelota 1 356 2.5E-114 T 23-10-2018 IPR004405 Translation release factor pelota GO:0070481|GO:0070966|GO:0071025 TON_0652 5772dc7d05ffd594c7a9c0dd63fb1af9 357 Hamap MF_01853 Protein pelota homolog [pelA]. 2 356 37.446 T 23-10-2018 IPR023521 Translation release factor pelota, archaea GO:0070481|GO:0070966|GO:0071025 TON_0652 5772dc7d05ffd594c7a9c0dd63fb1af9 357 Gene3D G3DSA:3.30.420.60 133 257 4.6E-37 T 23-10-2018 TON_0652 5772dc7d05ffd594c7a9c0dd63fb1af9 357 Pfam PF03465 eRF1 domain 3 261 356 8.7E-26 T 23-10-2018 IPR005142 eRF1 domain 3 TON_0652 5772dc7d05ffd594c7a9c0dd63fb1af9 357 SUPERFAMILY SSF159065 2 128 1.44E-35 T 23-10-2018 IPR038069 Pelota/DOM34, N-terminal domain TON_0652 5772dc7d05ffd594c7a9c0dd63fb1af9 357 SMART SM01194 1 129 2.1E-46 T 23-10-2018 IPR005140 eRF1 domain 1/Pelota-like TON_0652 5772dc7d05ffd594c7a9c0dd63fb1af9 357 SUPERFAMILY SSF55315 251 356 1.45E-29 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like TON_0652 5772dc7d05ffd594c7a9c0dd63fb1af9 357 Gene3D G3DSA:3.30.1330.30 258 357 4.7E-33 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like TON_0652 5772dc7d05ffd594c7a9c0dd63fb1af9 357 Pfam PF03464 eRF1 domain 2 136 248 8.1E-17 T 23-10-2018 IPR005141 eRF1 domain 2 TON_0652 5772dc7d05ffd594c7a9c0dd63fb1af9 357 SUPERFAMILY SSF53137 131 259 4.8E-33 T 23-10-2018 TON_0109 52bb0c2ade1e2d808fe0f5b88765ed52 65 Gene3D G3DSA:1.10.10.60 1 65 8.3E-33 T 23-10-2018 TON_0109 52bb0c2ade1e2d808fe0f5b88765ed52 65 SUPERFAMILY SSF46924 2 63 1.83E-27 T 23-10-2018 IPR023580 RNA polymerase subunit RPB10 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 TON_0109 52bb0c2ade1e2d808fe0f5b88765ed52 65 ProSitePatterns PS01112 RNA polymerases N / 8 Kd subunits signature. 2 11 - T 23-10-2018 IPR020789 RNA polymerases, subunit N, zinc binding site GO:0003677|GO:0003899|GO:0006351|GO:0008270 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 TON_0109 52bb0c2ade1e2d808fe0f5b88765ed52 65 PIRSF PIRSF005653 1 65 1.4E-31 T 23-10-2018 IPR000268 DNA-directed RNA polymerase, subunit N/Rpb10 GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 TON_0109 52bb0c2ade1e2d808fe0f5b88765ed52 65 ProDom PD006539 RNA POLYMERASE DNA-DIRECTED SUBUNIT TRANSFERASE NUCLEOTIDYLTRANSFERASE METAL-BINDING ZINC TRANSCRIPTION N 10 49 3.0E-14 T 23-10-2018 IPR000268 DNA-directed RNA polymerase, subunit N/Rpb10 GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 TON_0109 52bb0c2ade1e2d808fe0f5b88765ed52 65 Pfam PF01194 RNA polymerases N / 8 kDa subunit 2 58 3.8E-30 T 23-10-2018 IPR000268 DNA-directed RNA polymerase, subunit N/Rpb10 GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 TON_0109 52bb0c2ade1e2d808fe0f5b88765ed52 65 Hamap MF_00250 DNA-directed RNA polymerase subunit N [rpoN]. 1 63 23.699 T 23-10-2018 IPR000268 DNA-directed RNA polymerase, subunit N/Rpb10 GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 TON_0015 17a4febae8e9906d4e52fbcda28bef5f 235 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 45 228 6.9E-14 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TON_0015 17a4febae8e9906d4e52fbcda28bef5f 235 SUPERFAMILY SSF161098 9 231 1.27E-36 T 23-10-2018 IPR035906 MetI-like superfamily TON_0015 17a4febae8e9906d4e52fbcda28bef5f 235 Gene3D G3DSA:1.10.3720.10 3 233 1.2E-33 T 23-10-2018 IPR035906 MetI-like superfamily TON_0603 92fae6aeea96c89a11fa3e5365c782d6 349 SUPERFAMILY SSF54534 3 156 1.41E-41 T 23-10-2018 TON_0603 92fae6aeea96c89a11fa3e5365c782d6 349 Gene3D G3DSA:3.10.50.80 3 164 1.2E-51 T 23-10-2018 TON_0603 92fae6aeea96c89a11fa3e5365c782d6 349 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 3 154 5.4E-17 T 23-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain TON_0989 81e91aa98f7ec675460f07798f649914 712 SUPERFAMILY SSF52980 20 130 6.43E-9 T 23-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 TON_0989 81e91aa98f7ec675460f07798f649914 712 Pfam PF04471 Restriction endonuclease 19 124 4.9E-15 T 23-10-2018 IPR007560 Restriction endonuclease type IV, Mrr GO:0003677|GO:0004519|GO:0009307 TON_0566 aa3e077751309b5119cdfb0885961164 534 Gene3D G3DSA:3.90.870.20 328 533 8.9E-75 T 23-10-2018 IPR038152 Carbamoyltransferase, C-terminal domain superfamily TON_0566 aa3e077751309b5119cdfb0885961164 534 Pfam PF16861 Carbamoyltransferase C-terminus 364 533 2.8E-63 T 23-10-2018 IPR031730 Carbamoyltransferase, C-terminal TON_0566 aa3e077751309b5119cdfb0885961164 534 SUPERFAMILY SSF53067 11 313 1.28E-12 T 23-10-2018 TON_0566 aa3e077751309b5119cdfb0885961164 534 Pfam PF02543 Carbamoyltransferase N-terminus 87 310 4.2E-38 T 23-10-2018 IPR003696 Carbamoyltransferase GO:0003824|GO:0009058 TON_0566 aa3e077751309b5119cdfb0885961164 534 Pfam PF02543 Carbamoyltransferase N-terminus 2 70 2.5E-10 T 23-10-2018 IPR003696 Carbamoyltransferase GO:0003824|GO:0009058 TON_0566 aa3e077751309b5119cdfb0885961164 534 Gene3D G3DSA:3.30.420.40 9 310 2.0E-64 T 23-10-2018 TON_0566 aa3e077751309b5119cdfb0885961164 534 Gene3D G3DSA:3.30.420.350 95 303 2.0E-64 T 23-10-2018 TON_0285 33c5fe3fc2fbbf8141b243e04bff4044 230 Gene3D G3DSA:3.40.50.11750 7 123 2.4E-33 T 23-10-2018 TON_0285 33c5fe3fc2fbbf8141b243e04bff4044 230 TIGRFAM TIGR00075 hypD: hydrogenase expression/formation protein HypD 1 227 5.1E-82 T 23-10-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 TON_0285 33c5fe3fc2fbbf8141b243e04bff4044 230 Gene3D G3DSA:1.10.10.2140 178 230 2.1E-25 T 23-10-2018 TON_0285 33c5fe3fc2fbbf8141b243e04bff4044 230 Pfam PF01924 Hydrogenase formation hypA family 1 227 2.5E-84 T 23-10-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 TON_0927 c1322b9e6eab5dbc272a41f9adf5c39e 152 SUPERFAMILY SSF55620 10 150 6.12E-35 T 23-10-2018 TON_0927 c1322b9e6eab5dbc272a41f9adf5c39e 152 Gene3D G3DSA:3.30.479.10 13 150 1.0E-32 T 23-10-2018 IPR038418 6-pyruvoyl tetrahydropterin synthase/QueD superfamily Reactome: R-HSA-1474151 TON_0927 c1322b9e6eab5dbc272a41f9adf5c39e 152 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 10 149 3.0E-27 T 23-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 TON_1455 507d4a901d1656efb9aa580c765c3932 169 SUPERFAMILY SSF46785 69 158 4.19E-24 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TON_1455 507d4a901d1656efb9aa580c765c3932 169 Gene3D G3DSA:1.10.10.10 64 150 4.9E-22 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TON_1455 507d4a901d1656efb9aa580c765c3932 169 Gene3D G3DSA:1.10.10.10 1 63 1.1E-13 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TON_1455 507d4a901d1656efb9aa580c765c3932 169 Pfam PF01022 Bacterial regulatory protein, arsR family 76 120 2.2E-13 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TON_1455 507d4a901d1656efb9aa580c765c3932 169 Pfam PF13412 Winged helix-turn-helix DNA-binding 6 46 2.8E-7 T 23-10-2018 TON_1455 507d4a901d1656efb9aa580c765c3932 169 SUPERFAMILY SSF46785 4 60 3.85E-10 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TON_1455 507d4a901d1656efb9aa580c765c3932 169 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 70 85 6.2E-10 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TON_1455 507d4a901d1656efb9aa580c765c3932 169 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 117 132 6.2E-10 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TON_1455 507d4a901d1656efb9aa580c765c3932 169 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 102 117 6.2E-10 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TON_1455 507d4a901d1656efb9aa580c765c3932 169 SMART SM00418 68 148 3.0E-17 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TON_1271 7bbe8e79cf1401d67281f13bb2644b05 439 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 268 275 1.8E-17 T 23-10-2018 TON_1271 7bbe8e79cf1401d67281f13bb2644b05 439 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 229 243 1.8E-17 T 23-10-2018 TON_1271 7bbe8e79cf1401d67281f13bb2644b05 439 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 2 24 1.8E-17 T 23-10-2018 TON_1271 7bbe8e79cf1401d67281f13bb2644b05 439 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 145 170 1.8E-17 T 23-10-2018 TON_1271 7bbe8e79cf1401d67281f13bb2644b05 439 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 324 423 2.2E-16 T 23-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 TON_1271 7bbe8e79cf1401d67281f13bb2644b05 439 Gene3D G3DSA:3.50.50.60 2 331 2.4E-145 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TON_1271 7bbe8e79cf1401d67281f13bb2644b05 439 SUPERFAMILY SSF51905 1 191 3.05E-47 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TON_1271 7bbe8e79cf1401d67281f13bb2644b05 439 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 280 1.3E-68 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TON_1271 7bbe8e79cf1401d67281f13bb2644b05 439 Gene3D G3DSA:3.50.50.60 107 431 2.4E-145 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TON_1271 7bbe8e79cf1401d67281f13bb2644b05 439 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 98 116 1.9E-22 T 23-10-2018 TON_1271 7bbe8e79cf1401d67281f13bb2644b05 439 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 3 22 1.9E-22 T 23-10-2018 TON_1271 7bbe8e79cf1401d67281f13bb2644b05 439 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 145 163 1.9E-22 T 23-10-2018 TON_1271 7bbe8e79cf1401d67281f13bb2644b05 439 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 253 275 1.9E-22 T 23-10-2018 TON_1271 7bbe8e79cf1401d67281f13bb2644b05 439 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 228 244 1.9E-22 T 23-10-2018 TON_1271 7bbe8e79cf1401d67281f13bb2644b05 439 SUPERFAMILY SSF55424 316 437 1.2E-26 T 23-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 TON_1271 7bbe8e79cf1401d67281f13bb2644b05 439 SUPERFAMILY SSF51905 142 307 6.69E-34 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TON_0617 ef045d3ec751345bdc58307ad8fe1376 580 SUPERFAMILY SSF51713 4 355 2.22E-116 T 23-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 TON_0617 ef045d3ec751345bdc58307ad8fe1376 580 TIGRFAM TIGR00451 unchar_dom_2: uncharacterized domain 2 485 575 2.9E-10 T 23-10-2018 IPR004521 Uncharacterised domain CHP00451 GO:0003723 TON_0617 ef045d3ec751345bdc58307ad8fe1376 580 Hamap MF_01634 tRNA-guanine(15) transglycosylase [tgtA]. 6 531 48.511 T 23-10-2018 IPR004804 tRNA-guanine(15) transglycosylase GO:0006400|GO:0016763 MetaCyc: PWY-6711|MetaCyc: PWY-7923 TON_0617 ef045d3ec751345bdc58307ad8fe1376 580 Gene3D G3DSA:3.20.20.105 1 356 2.9E-125 T 23-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 TON_0617 ef045d3ec751345bdc58307ad8fe1376 580 Gene3D G3DSA:3.10.450.90 427 501 9.0E-27 T 23-10-2018 IPR038250 TGT, patch-forming C2 domain superfamily MetaCyc: PWY-6711|MetaCyc: PWY-7923 TON_0617 ef045d3ec751345bdc58307ad8fe1376 580 SMART SM00359 505 579 1.5E-22 T 23-10-2018 IPR002478 PUA domain GO:0003723 TON_0617 ef045d3ec751345bdc58307ad8fe1376 580 Gene3D G3DSA:3.90.1020.10 357 426 2.4E-29 T 23-10-2018 IPR038370 TGT, C1 domain superfamily MetaCyc: PWY-6711|MetaCyc: PWY-7923 TON_0617 ef045d3ec751345bdc58307ad8fe1376 580 SUPERFAMILY SSF88802 357 502 6.34E-41 T 23-10-2018 TON_0617 ef045d3ec751345bdc58307ad8fe1376 580 SUPERFAMILY SSF88697 504 578 4.53E-21 T 23-10-2018 IPR015947 PUA-like superfamily TON_0617 ef045d3ec751345bdc58307ad8fe1376 580 TIGRFAM TIGR00432 arcsn_tRNA_tgt: tRNA-guanine(15) transglycosylase 6 388 8.8E-172 T 23-10-2018 IPR004804 tRNA-guanine(15) transglycosylase GO:0006400|GO:0016763 MetaCyc: PWY-6711|MetaCyc: PWY-7923 TON_0617 ef045d3ec751345bdc58307ad8fe1376 580 Pfam PF01702 Queuine tRNA-ribosyltransferase 109 330 3.3E-41 T 23-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 TON_0617 ef045d3ec751345bdc58307ad8fe1376 580 Pfam PF14809 C1 domain of tRNA-guanine transglycosylase dimerisation 357 426 1.1E-44 T 23-10-2018 IPR032729 tRNA-guanine(15) transglycosylase, C1 domain MetaCyc: PWY-6711|MetaCyc: PWY-7923 TON_0617 ef045d3ec751345bdc58307ad8fe1376 580 TIGRFAM TIGR00449 tgt_general: tRNA-guanine family transglycosylase 6 337 8.3E-90 T 23-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 TON_0617 ef045d3ec751345bdc58307ad8fe1376 580 Gene3D G3DSA:2.30.130.10 502 579 9.8E-33 T 23-10-2018 IPR036974 PUA domain superfamily GO:0003723 TON_0617 ef045d3ec751345bdc58307ad8fe1376 580 Pfam PF01472 PUA domain 506 577 2.8E-17 T 23-10-2018 IPR002478 PUA domain GO:0003723 TON_0617 ef045d3ec751345bdc58307ad8fe1376 580 Pfam PF14810 Patch-forming domain C2 of tRNA-guanine transglycosylase 435 503 4.9E-22 T 23-10-2018 IPR029402 tRNA-guanine transglycosylase, patch-forming domain C2 MetaCyc: PWY-6711|MetaCyc: PWY-7923 TON_1509 7b829fca3a3b4a23021b7cac3d6cf824 310 SUPERFAMILY SSF53335 107 298 1.4E-34 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TON_1509 7b829fca3a3b4a23021b7cac3d6cf824 310 ProSitePatterns PS01184 ubiE/COQ5 methyltransferase family signature 2. 224 238 - T 23-10-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 TON_1509 7b829fca3a3b4a23021b7cac3d6cf824 310 Gene3D G3DSA:3.40.50.150 132 305 1.1E-33 T 23-10-2018 TON_1509 7b829fca3a3b4a23021b7cac3d6cf824 310 Pfam PF08241 Methyltransferase domain 140 234 1.7E-23 T 23-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 TON_0074 d4c9d2a2e7cb873259001e03033f0e8d 98 Pfam PF01253 Translation initiation factor SUI1 20 90 5.5E-21 T 23-10-2018 IPR001950 SUI1 domain GO:0003743|GO:0006413 TON_0074 d4c9d2a2e7cb873259001e03033f0e8d 98 SUPERFAMILY SSF55159 5 90 1.31E-24 T 23-10-2018 IPR036877 SUI1 domain superfamily GO:0003743|GO:0006413 TON_0074 d4c9d2a2e7cb873259001e03033f0e8d 98 Gene3D G3DSA:3.30.780.10 20 98 4.5E-29 T 23-10-2018 TON_0074 d4c9d2a2e7cb873259001e03033f0e8d 98 PIRSF PIRSF037511 5 97 2.2E-26 T 23-10-2018 IPR005872 Archaeal/bacterial translation initiation factor SUI1 GO:0003743 TON_0074 d4c9d2a2e7cb873259001e03033f0e8d 98 Hamap MF_00604 Protein translation factor SUI1 homolog. 2 93 26.682 T 23-10-2018 IPR022851 Translation factor SUI1 homolog, archaea TON_0074 d4c9d2a2e7cb873259001e03033f0e8d 98 TIGRFAM TIGR01158 SUI1_rel: putative translation initiation factor SUI1 4 97 3.2E-36 T 23-10-2018 IPR005872 Archaeal/bacterial translation initiation factor SUI1 GO:0003743 TON_1655 e493b45431c7a43d3ef715cbc03d439c 185 Pfam PF01661 Macro domain 20 145 5.7E-34 T 23-10-2018 IPR002589 Macro domain TON_1655 e493b45431c7a43d3ef715cbc03d439c 185 SMART SM00506 3 146 3.1E-50 T 23-10-2018 IPR002589 Macro domain TON_1655 e493b45431c7a43d3ef715cbc03d439c 185 Gene3D G3DSA:3.40.220.10 1 183 4.3E-54 T 23-10-2018 TON_1655 e493b45431c7a43d3ef715cbc03d439c 185 SUPERFAMILY SSF52949 6 181 4.71E-50 T 23-10-2018 TON_0055 b6355e66a1f0d8c524c0319f43e84319 334 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 229 240 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TON_0055 b6355e66a1f0d8c524c0319f43e84319 334 Gene3D G3DSA:1.10.1060.10 283 332 1.9E-5 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 TON_0055 b6355e66a1f0d8c524c0319f43e84319 334 Pfam PF17179 4Fe-4S dicluster domain 229 320 3.1E-24 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TON_0055 b6355e66a1f0d8c524c0319f43e84319 334 SUPERFAMILY SSF46548 218 332 1.5E-12 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 TON_0055 b6355e66a1f0d8c524c0319f43e84319 334 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 306 317 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TON_0025 3c041e279c3e3c45477353a9e2904de5 149 Gene3D G3DSA:3.30.428.10 1 140 3.9E-39 T 23-10-2018 IPR036265 HIT-like superfamily TON_0025 3c041e279c3e3c45477353a9e2904de5 149 Pfam PF01230 HIT domain 11 100 1.7E-24 T 23-10-2018 IPR001310 Histidine triad (HIT) protein TON_0025 3c041e279c3e3c45477353a9e2904de5 149 SUPERFAMILY SSF54197 1 132 3.4E-37 T 23-10-2018 IPR036265 HIT-like superfamily TON_0025 3c041e279c3e3c45477353a9e2904de5 149 ProSitePatterns PS00892 HIT domain signature. 81 99 - T 23-10-2018 IPR019808 Histidine triad, conserved site TON_1688 c930d27ff108edd19288fd86f54b2258 116 Gene3D G3DSA:2.30.130.30 2 109 3.9E-43 T 23-10-2018 TON_1688 c930d27ff108edd19288fd86f54b2258 116 PIRSF PIRSF016134 2 111 1.3E-45 T 23-10-2018 IPR016645 Uncharacterised conserved protein UCP016134 TON_1688 c930d27ff108edd19288fd86f54b2258 116 SMART SM01022 6 109 7.5E-14 T 23-10-2018 IPR007374 ASCH domain TON_1688 c930d27ff108edd19288fd86f54b2258 116 SUPERFAMILY SSF88697 1 108 4.31E-36 T 23-10-2018 IPR015947 PUA-like superfamily TON_1688 c930d27ff108edd19288fd86f54b2258 116 Pfam PF04266 ASCH domain 6 108 2.3E-15 T 23-10-2018 IPR007374 ASCH domain TON_0094 e833215facece291a61f50f941f758ae 83 Hamap MF_00721 50S ribosomal protein L14e [rpl14e]. 1 79 26.876 T 23-10-2018 IPR023651 Ribosomal protein L14e GO:0003735|GO:0005840|GO:0006412 TON_0094 e833215facece291a61f50f941f758ae 83 Gene3D G3DSA:2.30.30.30 2 83 2.9E-30 T 23-10-2018 IPR014722 Ribosomal protein L2, domain 2 TON_0094 e833215facece291a61f50f941f758ae 83 Pfam PF01929 Ribosomal protein L14 44 81 1.4E-4 T 23-10-2018 IPR002784 Ribosomal protein L14e domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0094 e833215facece291a61f50f941f758ae 83 SUPERFAMILY SSF50104 2 80 1.81E-20 T 23-10-2018 IPR008991 Translation protein SH3-like domain superfamily TON_1525 3d7290caf1cd7aebb64b77428a8cafb0 146 Pfam PF04545 Sigma-70, region 4 7 49 2.3E-6 T 23-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 TON_1525 3d7290caf1cd7aebb64b77428a8cafb0 146 Pfam PF14601 DNA_binding protein, TFX, C-term 52 132 1.4E-22 T 23-10-2018 IPR029291 DNA binding protein Tfx, C-terminal TON_1525 3d7290caf1cd7aebb64b77428a8cafb0 146 PIRSF PIRSF004932 3 146 1.9E-65 T 23-10-2018 IPR018384 DNA-binding protein Tfx, euryarchaeota GO:0003677 TON_1525 3d7290caf1cd7aebb64b77428a8cafb0 146 TIGRFAM TIGR00721 tfx: DNA-binding protein, Tfx family 1 137 2.3E-57 T 23-10-2018 IPR004645 DNA-binding protein Tfx, archaea GO:0003677 TON_1525 3d7290caf1cd7aebb64b77428a8cafb0 146 SUPERFAMILY SSF89915 17 120 6.93E-23 T 23-10-2018 IPR036657 DNA-binding protein Tfx superfamily, archaea GO:0003677 TON_1525 3d7290caf1cd7aebb64b77428a8cafb0 146 Gene3D G3DSA:3.30.1190.10 17 135 7.3E-36 T 23-10-2018 IPR036657 DNA-binding protein Tfx superfamily, archaea GO:0003677 TON_1799 41c5657a71457978bd57fe5b08459ca3 120 Pfam PF01900 Rpp14/Pop5 family 17 113 1.8E-23 T 23-10-2018 IPR002759 Ribonuclease P/MRP protein subunit GO:0004540|GO:0008033 Reactome: R-HSA-6784531 TON_1799 41c5657a71457978bd57fe5b08459ca3 120 Hamap MF_00755 Ribonuclease P protein component 2 [rnp2]. 5 116 27.066 T 23-10-2018 IPR002759 Ribonuclease P/MRP protein subunit GO:0004540|GO:0008033 Reactome: R-HSA-6784531 TON_1799 41c5657a71457978bd57fe5b08459ca3 120 PIRSF PIRSF004952 4 120 5.0E-47 T 23-10-2018 IPR016434 Ribonuclease P, protein component 2 GO:0001682|GO:0004526 TON_1799 41c5657a71457978bd57fe5b08459ca3 120 SUPERFAMILY SSF160350 4 117 1.12E-35 T 23-10-2018 IPR038085 Rnp2-like domain superfamily Reactome: R-HSA-6784531 TON_1799 41c5657a71457978bd57fe5b08459ca3 120 Gene3D G3DSA:3.30.70.3250 1 120 1.0E-49 T 23-10-2018 IPR038085 Rnp2-like domain superfamily Reactome: R-HSA-6784531 TON_0141 b38727a7fd465cd46d9717039212435e 967 SUPERFAMILY SSF52374 4 694 2.33E-100 T 23-10-2018 TON_0141 b38727a7fd465cd46d9717039212435e 967 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 12 689 3.8E-67 T 23-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 TON_0141 b38727a7fd465cd46d9717039212435e 967 SUPERFAMILY SSF47323 713 908 1.18E-39 T 23-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 TON_0141 b38727a7fd465cd46d9717039212435e 967 SUPERFAMILY SSF50677 210 443 1.22E-33 T 23-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 TON_0141 b38727a7fd465cd46d9717039212435e 967 Gene3D G3DSA:1.10.10.720 866 917 6.4E-48 T 23-10-2018 TON_0141 b38727a7fd465cd46d9717039212435e 967 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 43 54 - T 23-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 TON_0141 b38727a7fd465cd46d9717039212435e 967 Gene3D G3DSA:3.40.50.620 9 688 1.7E-302 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TON_0141 b38727a7fd465cd46d9717039212435e 967 TIGRFAM TIGR00395 leuS_arch: leucine--tRNA ligase 8 967 0.0 T 23-10-2018 IPR004493 Leucyl-tRNA synthetase, class Ia, archaeal/eukaryotic cytosolic GO:0000166|GO:0004823|GO:0005524|GO:0005737|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 TON_0141 b38727a7fd465cd46d9717039212435e 967 Hamap MF_00049_A Leucine--tRNA ligase [leuS]. 6 967 18.429 T 23-10-2018 IPR020791 Leucine-tRNA ligase, archaeal GO:0000166|GO:0004823|GO:0005524|GO:0005737|GO:0006429 KEGG: 00970+6.1.1.4 TON_0141 b38727a7fd465cd46d9717039212435e 967 Gene3D G3DSA:1.10.730.10 690 810 2.4E-35 T 23-10-2018 TON_0141 b38727a7fd465cd46d9717039212435e 967 Gene3D G3DSA:3.90.740.10 205 451 1.7E-302 T 23-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 TON_0141 b38727a7fd465cd46d9717039212435e 967 Gene3D G3DSA:3.30.2320.20 835 967 6.4E-48 T 23-10-2018 TON_0141 b38727a7fd465cd46d9717039212435e 967 Pfam PF08264 Anticodon-binding domain of tRNA 726 859 3.1E-31 T 23-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 TON_1952 e43016ef1b29f1b18d876f4e96d4ef63 268 Pfam PF01336 OB-fold nucleic acid binding domain 47 115 2.1E-8 T 23-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 TON_1952 e43016ef1b29f1b18d876f4e96d4ef63 268 SUPERFAMILY SSF50249 33 131 4.68E-11 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold TON_1952 e43016ef1b29f1b18d876f4e96d4ef63 268 Gene3D G3DSA:2.40.50.140 9 141 1.9E-13 T 23-10-2018 TON_0069 5e3b4234379e149bb0939e65ee85f484 239 Gene3D G3DSA:2.30.30.30 85 162 1.7E-29 T 23-10-2018 IPR014722 Ribosomal protein L2, domain 2 TON_0069 5e3b4234379e149bb0939e65ee85f484 239 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 92 222 5.7E-42 T 23-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 TON_0069 5e3b4234379e149bb0939e65ee85f484 239 Gene3D G3DSA:4.10.950.10 163 239 3.4E-34 T 23-10-2018 IPR014726 Ribosomal protein L2, domain 3 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0069 5e3b4234379e149bb0939e65ee85f484 239 Hamap MF_01320_A 50S ribosomal protein L2 [rplB]. 1 238 42.439 T 23-10-2018 IPR023672 Ribosomal protein L2, archaeal-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0069 5e3b4234379e149bb0939e65ee85f484 239 PIRSF PIRSF002158 1 239 6.8E-73 T 23-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TON_0069 5e3b4234379e149bb0939e65ee85f484 239 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 11 84 2.1E-20 T 23-10-2018 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 TON_0069 5e3b4234379e149bb0939e65ee85f484 239 Gene3D G3DSA:2.40.50.140 1 81 2.8E-31 T 23-10-2018 TON_0069 5e3b4234379e149bb0939e65ee85f484 239 SMART SM01382 91 223 4.5E-61 T 23-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 TON_0069 5e3b4234379e149bb0939e65ee85f484 239 SUPERFAMILY SSF50249 2 93 1.13E-23 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold TON_0069 5e3b4234379e149bb0939e65ee85f484 239 SMART SM01383 11 85 1.0E-25 T 23-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TON_0069 5e3b4234379e149bb0939e65ee85f484 239 SUPERFAMILY SSF50104 94 237 4.15E-47 T 23-10-2018 IPR008991 Translation protein SH3-like domain superfamily TON_1314 3333721882b2100f030dd438f211b62b 224 SUPERFAMILY SSF56281 1 223 1.3E-38 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TON_1314 3333721882b2100f030dd438f211b62b 224 Hamap MF_00457 UPF0173 metal-dependent hydrolase . 2 224 39.26 T 23-10-2018 IPR022877 Protein of unknown funcion UPF0173 TON_1314 3333721882b2100f030dd438f211b62b 224 Pfam PF13483 Beta-lactamase superfamily domain 3 189 7.1E-32 T 23-10-2018 TON_1314 3333721882b2100f030dd438f211b62b 224 SMART SM00849 8 189 2.5E-18 T 23-10-2018 IPR001279 Metallo-beta-lactamase TON_1314 3333721882b2100f030dd438f211b62b 224 Gene3D G3DSA:3.60.15.10 2 224 3.2E-73 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TON_0223 bdc03c3d7fbbbbdd547bd5c174972bbc 215 Gene3D G3DSA:1.10.455.10 15 215 1.4E-80 T 23-10-2018 IPR036823 Ribosomal protein S7 domain superfamily TON_0223 bdc03c3d7fbbbbdd547bd5c174972bbc 215 TIGRFAM TIGR01028 uS7_euk_arch: ribosomal protein uS7 14 215 1.1E-89 T 23-10-2018 IPR005716 Ribosomal protein S5/S7, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0223 bdc03c3d7fbbbbdd547bd5c174972bbc 215 Hamap MF_00480_A 30S ribosomal protein S7 [rpsG]. 15 215 38.73 T 23-10-2018 IPR026018 Ribosomal protein S7, archaeal TON_0223 bdc03c3d7fbbbbdd547bd5c174972bbc 215 SUPERFAMILY SSF47973 16 215 1.96E-64 T 23-10-2018 IPR036823 Ribosomal protein S7 domain superfamily TON_0223 bdc03c3d7fbbbbdd547bd5c174972bbc 215 PIRSF PIRSF002122 1 215 7.3E-49 T 23-10-2018 IPR000235 Ribosomal protein S5/S7 GO:0006412 TON_0223 bdc03c3d7fbbbbdd547bd5c174972bbc 215 Pfam PF00177 Ribosomal protein S7p/S5e 54 215 1.3E-39 T 23-10-2018 IPR023798 Ribosomal protein S7 domain TON_1391 c00d7499cebc4223dc6c0b0ec884064a 394 Gene3D G3DSA:1.20.1250.20 3 381 7.3E-52 T 23-10-2018 TON_1391 c00d7499cebc4223dc6c0b0ec884064a 394 PRINTS PR01035 Tetracycline resistance protein signature 44 63 3.0E-9 T 23-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 TON_1391 c00d7499cebc4223dc6c0b0ec884064a 394 PRINTS PR01035 Tetracycline resistance protein signature 15 31 3.0E-9 T 23-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 TON_1391 c00d7499cebc4223dc6c0b0ec884064a 394 PRINTS PR01035 Tetracycline resistance protein signature 298 318 3.0E-9 T 23-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 TON_1391 c00d7499cebc4223dc6c0b0ec884064a 394 PRINTS PR01035 Tetracycline resistance protein signature 133 155 3.0E-9 T 23-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 TON_1391 c00d7499cebc4223dc6c0b0ec884064a 394 Pfam PF07690 Major Facilitator Superfamily 12 328 3.0E-40 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TON_1391 c00d7499cebc4223dc6c0b0ec884064a 394 SUPERFAMILY SSF103473 4 382 1.96E-61 T 23-10-2018 IPR036259 MFS transporter superfamily TON_0263 22662345293d0b2fe1c8d581ae37ea49 158 PRINTS PR00446 Hydrogen uptake protein signature 67 77 1.3E-7 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 TON_0263 22662345293d0b2fe1c8d581ae37ea49 158 PRINTS PR00446 Hydrogen uptake protein signature 25 36 1.3E-7 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 TON_0263 22662345293d0b2fe1c8d581ae37ea49 158 PRINTS PR00446 Hydrogen uptake protein signature 13 25 1.3E-7 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 TON_0263 22662345293d0b2fe1c8d581ae37ea49 158 TIGRFAM TIGR00072 hydrog_prot: hydrogenase maturation protease 14 153 2.4E-33 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 TON_0263 22662345293d0b2fe1c8d581ae37ea49 158 Pfam PF01750 Hydrogenase maturation protease 31 131 1.8E-15 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 TON_0263 22662345293d0b2fe1c8d581ae37ea49 158 Gene3D G3DSA:3.40.50.1450 8 157 9.6E-44 T 23-10-2018 IPR023430 Peptidase HybD-like domain superfamily TON_0263 22662345293d0b2fe1c8d581ae37ea49 158 SUPERFAMILY SSF53163 11 155 8.76E-33 T 23-10-2018 IPR023430 Peptidase HybD-like domain superfamily TON_1445 a6fef4f556c867bbe9ba50e354a518b3 449 SUPERFAMILY SSF53738 150 249 2.94E-23 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TON_1445 a6fef4f556c867bbe9ba50e354a518b3 449 SUPERFAMILY SSF53738 2 140 2.18E-46 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TON_1445 a6fef4f556c867bbe9ba50e354a518b3 449 SUPERFAMILY SSF55957 348 446 1.83E-23 T 23-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TON_1445 a6fef4f556c867bbe9ba50e354a518b3 449 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 90 99 - T 23-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TON_1445 a6fef4f556c867bbe9ba50e354a518b3 449 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 226 241 2.3E-14 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TON_1445 a6fef4f556c867bbe9ba50e354a518b3 449 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 165 184 2.3E-14 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TON_1445 a6fef4f556c867bbe9ba50e354a518b3 449 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 89 103 2.3E-14 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TON_1445 a6fef4f556c867bbe9ba50e354a518b3 449 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 163 246 1.9E-19 T 23-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TON_1445 a6fef4f556c867bbe9ba50e354a518b3 449 Gene3D G3DSA:3.40.120.10 247 330 7.5E-55 T 23-10-2018 TON_1445 a6fef4f556c867bbe9ba50e354a518b3 449 Gene3D G3DSA:3.40.120.10 164 345 7.5E-55 T 23-10-2018 TON_1445 a6fef4f556c867bbe9ba50e354a518b3 449 Gene3D G3DSA:3.30.310.50 360 448 7.9E-22 T 23-10-2018 TON_1445 a6fef4f556c867bbe9ba50e354a518b3 449 Hamap MF_01554_A Phosphoglucosamine mutase [glmM]. 2 446 52.093 T 23-10-2018 IPR023666 Phosphoglucosamine mutase, archaeal GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TON_1445 a6fef4f556c867bbe9ba50e354a518b3 449 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 254 357 5.0E-19 T 23-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TON_1445 a6fef4f556c867bbe9ba50e354a518b3 449 SUPERFAMILY SSF53738 252 355 1.33E-22 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TON_1445 a6fef4f556c867bbe9ba50e354a518b3 449 TIGRFAM TIGR03990 Arch_GlmM: phosphoglucosamine mutase 3 441 1.9E-163 T 23-10-2018 IPR024086 Phosphoglucosamine mutase, archaeal type GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TON_1445 a6fef4f556c867bbe9ba50e354a518b3 449 Gene3D G3DSA:3.40.120.10 1 147 1.8E-51 T 23-10-2018 TON_1445 a6fef4f556c867bbe9ba50e354a518b3 449 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 3 132 3.8E-45 T 23-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TON_1445 a6fef4f556c867bbe9ba50e354a518b3 449 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 366 440 2.6E-8 T 23-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TON_0359 795576bf64d36c7ece058f94ae5a24f9 419 SUPERFAMILY SSF51161 243 409 2.36E-39 T 23-10-2018 IPR011004 Trimeric LpxA-like superfamily TON_0359 795576bf64d36c7ece058f94ae5a24f9 419 SUPERFAMILY SSF53448 2 312 1.42E-71 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TON_0359 795576bf64d36c7ece058f94ae5a24f9 419 Pfam PF00483 Nucleotidyl transferase 2 232 8.2E-39 T 23-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 TON_0359 795576bf64d36c7ece058f94ae5a24f9 419 Gene3D G3DSA:3.90.550.10 1 224 3.2E-53 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TON_0359 795576bf64d36c7ece058f94ae5a24f9 419 TIGRFAM TIGR03992 Arch_glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 2 398 2.3E-155 T 23-10-2018 IPR023915 UDP-GlcNAc diphosphorylase/GlcNAc-1-P N-acetyltransferase, GlmU, archaeal-type GO:0003977|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|MetaCyc: PWY-5514 TON_0359 795576bf64d36c7ece058f94ae5a24f9 419 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 365 399 8.5E-7 T 23-10-2018 IPR001451 Hexapeptide repeat TON_0359 795576bf64d36c7ece058f94ae5a24f9 419 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 254 287 2.7E-10 T 23-10-2018 IPR001451 Hexapeptide repeat TON_0359 795576bf64d36c7ece058f94ae5a24f9 419 Gene3D G3DSA:2.160.10.10 225 410 2.6E-59 T 23-10-2018 TON_1069 b997b29f93e84ae3a9363451ca046f66 789 SUPERFAMILY SSF52540 52 480 1.86E-59 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_1069 b997b29f93e84ae3a9363451ca046f66 789 SUPERFAMILY SSF52980 577 706 9.38E-38 T 23-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 TON_1069 b997b29f93e84ae3a9363451ca046f66 789 Pfam PF00270 DEAD/DEAH box helicase 14 151 1.7E-19 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 TON_1069 b997b29f93e84ae3a9363451ca046f66 789 Pfam PF00271 Helicase conserved C-terminal domain 344 460 3.0E-24 T 23-10-2018 IPR001650 Helicase, C-terminal TON_1069 b997b29f93e84ae3a9363451ca046f66 789 Gene3D G3DSA:3.40.50.300 1 199 1.6E-72 T 23-10-2018 TON_1069 b997b29f93e84ae3a9363451ca046f66 789 Pfam PF02732 ERCC4 domain 581 699 1.8E-28 T 23-10-2018 IPR006166 ERCC4 domain GO:0003677|GO:0004518 Reactome: R-HSA-6783310 TON_1069 b997b29f93e84ae3a9363451ca046f66 789 Gene3D G3DSA:3.40.50.300 209 478 1.0E-99 T 23-10-2018 TON_1069 b997b29f93e84ae3a9363451ca046f66 789 SMART SM00278 729 748 850.0 T 23-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 TON_1069 b997b29f93e84ae3a9363451ca046f66 789 SMART SM00278 761 780 0.0099 T 23-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 TON_1069 b997b29f93e84ae3a9363451ca046f66 789 SMART SM00490 372 461 1.0E-23 T 23-10-2018 IPR001650 Helicase, C-terminal TON_1069 b997b29f93e84ae3a9363451ca046f66 789 Pfam PF12826 Helix-hairpin-helix motif 733 784 1.9E-10 T 23-10-2018 TON_1069 b997b29f93e84ae3a9363451ca046f66 789 Gene3D G3DSA:3.40.50.10130 575 715 2.1E-53 T 23-10-2018 TON_1069 b997b29f93e84ae3a9363451ca046f66 789 Gene3D G3DSA:1.10.150.20 716 789 8.5E-24 T 23-10-2018 TON_1069 b997b29f93e84ae3a9363451ca046f66 789 Gene3D G3DSA:1.20.1320.20 212 338 1.0E-99 T 23-10-2018 TON_1069 b997b29f93e84ae3a9363451ca046f66 789 SMART SM00891 578 658 5.4E-31 T 23-10-2018 IPR006166 ERCC4 domain GO:0003677|GO:0004518 Reactome: R-HSA-6783310 TON_1069 b997b29f93e84ae3a9363451ca046f66 789 SUPERFAMILY SSF47781 716 785 2.78E-16 T 23-10-2018 IPR010994 RuvA domain 2-like TON_1069 b997b29f93e84ae3a9363451ca046f66 789 SMART SM00487 6 201 1.9E-30 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TON_1234 0971d25fc435352575619ef6ce8fae28 444 Hamap MF_01133 Ribulose bisphosphate carboxylase [rbcL]. 10 439 52.916 T 23-10-2018 IPR017712 Ribulose bisphosphate carboxylase, type III GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 TON_1234 0971d25fc435352575619ef6ce8fae28 444 SUPERFAMILY SSF54966 3 136 1.1E-37 T 23-10-2018 IPR036422 RuBisCO large subunit, N-terminal domain superfamily GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 TON_1234 0971d25fc435352575619ef6ce8fae28 444 Pfam PF02788 Ribulose bisphosphate carboxylase large chain, N-terminal domain 12 131 4.3E-45 T 23-10-2018 IPR017443 Ribulose bisphosphate carboxylase, large subunit, ferrodoxin-like N-terminal GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 TON_1234 0971d25fc435352575619ef6ce8fae28 444 Gene3D G3DSA:3.20.20.110 137 438 5.1E-126 T 23-10-2018 IPR036376 Ribulose bisphosphate carboxylase, large subunit, C-terminal domain superfamily GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 TON_1234 0971d25fc435352575619ef6ce8fae28 444 SUPERFAMILY SSF51649 136 441 5.76E-107 T 23-10-2018 IPR036376 Ribulose bisphosphate carboxylase, large subunit, C-terminal domain superfamily GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 TON_1234 0971d25fc435352575619ef6ce8fae28 444 Pfam PF00016 Ribulose bisphosphate carboxylase large chain, catalytic domain 142 438 4.4E-96 T 23-10-2018 IPR000685 Ribulose bisphosphate carboxylase, large subunit, C-terminal GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 TON_1234 0971d25fc435352575619ef6ce8fae28 444 TIGRFAM TIGR03326 rubisco_III: ribulose bisphosphate carboxylase, type III 11 438 2.4E-220 T 23-10-2018 IPR017712 Ribulose bisphosphate carboxylase, type III GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 TON_1234 0971d25fc435352575619ef6ce8fae28 444 Gene3D G3DSA:3.30.70.150 1 136 2.1E-45 T 23-10-2018 IPR036422 RuBisCO large subunit, N-terminal domain superfamily GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 TON_1651 42b5c8598a4062b38c65a59222e0b0f4 257 Gene3D G3DSA:3.40.50.1580 1 257 7.2E-102 T 23-10-2018 TON_1651 42b5c8598a4062b38c65a59222e0b0f4 257 TIGRFAM TIGR01694 MTAP: methylthioadenosine phosphorylase 4 237 3.8E-100 T 23-10-2018 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112|Reactome: R-HSA-8950505 TON_1651 42b5c8598a4062b38c65a59222e0b0f4 257 ProSitePatterns PS01240 Purine and other phosphorylases family 2 signature. 48 88 - T 23-10-2018 IPR018099 Purine phosphorylase, family 2, conserved site GO:0016763 TON_1651 42b5c8598a4062b38c65a59222e0b0f4 257 Hamap MF_01963 S-methyl-5'-thioadenosine phosphorylase [mtnP]. 2 257 44.792 T 23-10-2018 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112|Reactome: R-HSA-8950505 TON_1651 42b5c8598a4062b38c65a59222e0b0f4 257 Pfam PF01048 Phosphorylase superfamily 3 235 2.6E-49 T 23-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 TON_1651 42b5c8598a4062b38c65a59222e0b0f4 257 SUPERFAMILY SSF53167 1 255 8.64E-92 T 23-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 TON_1646 c33358f748b9f6bf4eb401db54727e17 338 PRINTS PR00169 Potassium channel signature 74 100 8.3E-8 T 23-10-2018 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 TON_1646 c33358f748b9f6bf4eb401db54727e17 338 PRINTS PR00169 Potassium channel signature 45 67 8.3E-8 T 23-10-2018 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 TON_1646 c33358f748b9f6bf4eb401db54727e17 338 Gene3D G3DSA:1.10.287.70 4 116 1.8E-21 T 23-10-2018 TON_1646 c33358f748b9f6bf4eb401db54727e17 338 Pfam PF07885 Ion channel 30 101 1.9E-17 T 23-10-2018 IPR013099 Potassium channel domain TON_1646 c33358f748b9f6bf4eb401db54727e17 338 Gene3D G3DSA:3.40.50.720 117 255 9.0E-28 T 23-10-2018 TON_1646 c33358f748b9f6bf4eb401db54727e17 338 PRINTS PR01333 Two pore domain K+ channel signature 121 130 1.8E-7 T 23-10-2018 IPR003280 Two pore domain potassium channel GO:0005267|GO:0016020|GO:0071805 Reactome: R-HSA-5576886 TON_1646 c33358f748b9f6bf4eb401db54727e17 338 PRINTS PR01333 Two pore domain K+ channel signature 57 85 1.8E-7 T 23-10-2018 IPR003280 Two pore domain potassium channel GO:0005267|GO:0016020|GO:0071805 Reactome: R-HSA-5576886 TON_1646 c33358f748b9f6bf4eb401db54727e17 338 SUPERFAMILY SSF81324 14 137 3.79E-29 T 23-10-2018 TON_1646 c33358f748b9f6bf4eb401db54727e17 338 SUPERFAMILY SSF51735 116 264 2.98E-21 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TON_1646 c33358f748b9f6bf4eb401db54727e17 338 Pfam PF02254 TrkA-N domain 121 241 5.4E-18 T 23-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 TON_0108 3670b3c53d54a054af327eeb089b42bd 135 SUPERFAMILY SSF54211 3 135 6.07E-34 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TON_0108 3670b3c53d54a054af327eeb089b42bd 135 TIGRFAM TIGR03627 uS9_arch: ribosomal protein uS9 3 135 7.9E-62 T 23-10-2018 IPR019958 Ribosomal protein S9, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 TON_0108 3670b3c53d54a054af327eeb089b42bd 135 ProSitePatterns PS00360 Ribosomal protein S9 signature. 68 86 - T 23-10-2018 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 TON_0108 3670b3c53d54a054af327eeb089b42bd 135 Hamap MF_00532_A 30S ribosomal protein S9 [rpsI]. 3 135 37.18 T 23-10-2018 IPR019958 Ribosomal protein S9, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 TON_0108 3670b3c53d54a054af327eeb089b42bd 135 Pfam PF00380 Ribosomal protein S9/S16 8 135 1.1E-30 T 23-10-2018 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 TON_0108 3670b3c53d54a054af327eeb089b42bd 135 Gene3D G3DSA:3.30.230.10 1 135 5.5E-51 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TON_1097 4874bc532c58f110467fde509d6c3879 461 SMART SM00881 6 105 5.1E-38 T 23-10-2018 IPR003781 CoA-binding GO:0048037 TON_1097 4874bc532c58f110467fde509d6c3879 461 Gene3D G3DSA:3.40.50.720 1 134 1.4E-45 T 23-10-2018 TON_1097 4874bc532c58f110467fde509d6c3879 461 SUPERFAMILY SSF52210 136 295 1.96E-44 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TON_1097 4874bc532c58f110467fde509d6c3879 461 SUPERFAMILY SSF51735 3 134 5.4E-37 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TON_1097 4874bc532c58f110467fde509d6c3879 461 TIGRFAM TIGR02717 AcCoA-syn-alpha: acetyl coenzyme A synthetase (ADP forming), alpha domain 3 452 8.5E-186 T 23-10-2018 IPR014089 Acetate-CoA ligase [ADP-forming], alpha domain KEGG: 00010+6.2.1.13|KEGG: 00620+6.2.1.13|KEGG: 00640+6.2.1.13|MetaCyc: PWY-5483|MetaCyc: PWY-5535 TON_1097 4874bc532c58f110467fde509d6c3879 461 Gene3D G3DSA:3.40.50.261 135 296 9.6E-64 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TON_1097 4874bc532c58f110467fde509d6c3879 461 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 156 293 9.8E-55 T 23-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain TON_1097 4874bc532c58f110467fde509d6c3879 461 SUPERFAMILY SSF52210 299 457 1.83E-33 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TON_1097 4874bc532c58f110467fde509d6c3879 461 Gene3D G3DSA:3.40.50.261 297 460 1.6E-50 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TON_1097 4874bc532c58f110467fde509d6c3879 461 Pfam PF13380 CoA binding domain 10 139 3.3E-21 T 23-10-2018 IPR003781 CoA-binding GO:0048037 TON_1647 264f4191715f0cfe35cfcd74bd123de5 353 SUPERFAMILY SSF47794 37 97 1.88E-13 T 23-10-2018 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 TON_1647 264f4191715f0cfe35cfcd74bd123de5 353 Pfam PF08423 Rad51 101 353 6.0E-94 T 23-10-2018 IPR013632 DNA recombination and repair protein Rad51-like, C-terminal Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579 TON_1647 264f4191715f0cfe35cfcd74bd123de5 353 Gene3D G3DSA:1.10.150.20 39 102 2.2E-25 T 23-10-2018 TON_1647 264f4191715f0cfe35cfcd74bd123de5 353 Hamap MF_00348 DNA repair and recombination protein RadA [radA]. 38 353 81.218 T 23-10-2018 IPR011938 DNA recombination/repair protein RadA GO:0003684|GO:0005524|GO:0006281|GO:0006310|GO:0008094 TON_1647 264f4191715f0cfe35cfcd74bd123de5 353 Pfam PF14520 Helix-hairpin-helix domain 39 94 3.3E-12 T 23-10-2018 TON_1647 264f4191715f0cfe35cfcd74bd123de5 353 SMART SM00382 134 323 4.2E-10 T 23-10-2018 IPR003593 AAA+ ATPase domain TON_1647 264f4191715f0cfe35cfcd74bd123de5 353 SMART SM00278 39 58 0.011 T 23-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 TON_1647 264f4191715f0cfe35cfcd74bd123de5 353 SMART SM00278 72 91 360.0 T 23-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 TON_1647 264f4191715f0cfe35cfcd74bd123de5 353 SUPERFAMILY SSF52540 115 352 3.83E-60 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_1647 264f4191715f0cfe35cfcd74bd123de5 353 Gene3D G3DSA:3.40.50.300 103 353 8.3E-86 T 23-10-2018 TON_1647 264f4191715f0cfe35cfcd74bd123de5 353 PIRSF PIRSF005856 28 353 4.8E-137 T 23-10-2018 IPR016467 DNA recombination and repair protein, RecA-like Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579 TON_1647 264f4191715f0cfe35cfcd74bd123de5 353 TIGRFAM TIGR02236 recomb_radA: DNA repair and recombination protein RadA 41 353 2.8E-165 T 23-10-2018 IPR011938 DNA recombination/repair protein RadA GO:0003684|GO:0005524|GO:0006281|GO:0006310|GO:0008094 TON_0143 55188fc7a8c24b377a775b325fc6e722 356 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 286 298 - T 23-10-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site TON_0143 55188fc7a8c24b377a775b325fc6e722 356 PRINTS PR00599 Methionine aminopeptidase-1 signature 308 320 6.8E-5 T 23-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 TON_0143 55188fc7a8c24b377a775b325fc6e722 356 PRINTS PR00599 Methionine aminopeptidase-1 signature 210 226 6.8E-5 T 23-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 TON_0143 55188fc7a8c24b377a775b325fc6e722 356 Gene3D G3DSA:3.90.230.10 131 356 5.6E-82 T 23-10-2018 TON_0143 55188fc7a8c24b377a775b325fc6e722 356 SUPERFAMILY SSF53092 2 129 1.4E-12 T 23-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal TON_0143 55188fc7a8c24b377a775b325fc6e722 356 Pfam PF00557 Metallopeptidase family M24 139 338 8.7E-67 T 23-10-2018 IPR000994 Peptidase M24 TON_0143 55188fc7a8c24b377a775b325fc6e722 356 SUPERFAMILY SSF55920 130 356 1.7E-75 T 23-10-2018 IPR036005 Creatinase/aminopeptidase-like TON_0143 55188fc7a8c24b377a775b325fc6e722 356 Gene3D G3DSA:3.40.350.10 1 129 3.7E-30 T 23-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal TON_0143 55188fc7a8c24b377a775b325fc6e722 356 Pfam PF01321 Creatinase/Prolidase N-terminal domain 2 131 3.8E-16 T 23-10-2018 IPR000587 Creatinase, N-terminal GO:0016787 TON_1818 8f6fee2ac4bd8dfd49a7c94b9e0f0b6f 268 Gene3D G3DSA:3.40.50.1000 69 184 3.4E-93 T 23-10-2018 IPR023214 HAD superfamily TON_1818 8f6fee2ac4bd8dfd49a7c94b9e0f0b6f 268 Pfam PF13344 Haloacid dehalogenase-like hydrolase 4 103 1.1E-29 T 23-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA TON_1818 8f6fee2ac4bd8dfd49a7c94b9e0f0b6f 268 PIRSF PIRSF000915 3 262 2.8E-68 T 23-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA TON_1818 8f6fee2ac4bd8dfd49a7c94b9e0f0b6f 268 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 5 232 5.8E-48 T 23-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA TON_1818 8f6fee2ac4bd8dfd49a7c94b9e0f0b6f 268 Pfam PF13242 HAD-hyrolase-like 184 256 1.7E-20 T 23-10-2018 TON_1818 8f6fee2ac4bd8dfd49a7c94b9e0f0b6f 268 SUPERFAMILY SSF56784 4 257 1.53E-67 T 23-10-2018 IPR036412 HAD-like superfamily TON_1818 8f6fee2ac4bd8dfd49a7c94b9e0f0b6f 268 Gene3D G3DSA:3.40.50.1000 5 250 3.4E-93 T 23-10-2018 IPR023214 HAD superfamily TON_0595 02d88093f97727940cfd37a2ff1292c2 508 ProSitePatterns PS00211 ABC transporters family signature. 407 421 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TON_0595 02d88093f97727940cfd37a2ff1292c2 508 Pfam PF00005 ABC transporter 278 434 5.2E-16 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TON_0595 02d88093f97727940cfd37a2ff1292c2 508 SUPERFAMILY SSF52540 238 495 1.51E-45 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_0595 02d88093f97727940cfd37a2ff1292c2 508 SUPERFAMILY SSF52540 5 231 1.89E-58 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_0595 02d88093f97727940cfd37a2ff1292c2 508 Gene3D G3DSA:3.40.50.300 2 241 7.9E-56 T 23-10-2018 TON_0595 02d88093f97727940cfd37a2ff1292c2 508 Gene3D G3DSA:3.40.50.300 257 502 4.1E-43 T 23-10-2018 TON_0595 02d88093f97727940cfd37a2ff1292c2 508 SMART SM00382 32 221 2.1E-15 T 23-10-2018 IPR003593 AAA+ ATPase domain TON_0595 02d88093f97727940cfd37a2ff1292c2 508 Pfam PF00005 ABC transporter 23 173 2.6E-29 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TON_0844 2cafb1218b26d738c33bc67660e91078 125 SUPERFAMILY SSF103247 2 125 7.32E-17 T 23-10-2018 IPR035923 TT1751-like domain superfamily TON_0844 2cafb1218b26d738c33bc67660e91078 125 Gene3D G3DSA:3.30.310.70 1 125 4.2E-12 T 23-10-2018 IPR035923 TT1751-like domain superfamily TON_0844 2cafb1218b26d738c33bc67660e91078 125 Pfam PF03625 Domain of unknown function DUF302 49 88 1.3E-5 T 23-10-2018 IPR005180 Domain of unknown function DUF302 TON_1440 10acf9edb2ec2aabbd3da6dfbff4e98c 197 Gene3D G3DSA:1.10.1760.20 5 195 4.9E-18 T 23-10-2018 TON_0354 158e501361632bdc03693e3be4b26e26 130 ProSitePatterns PS01193 Ribosomal protein S8e signature. 10 29 - T 23-10-2018 IPR018283 Ribosomal protein S8e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0354 158e501361632bdc03693e3be4b26e26 130 Hamap MF_00029 30S ribosomal protein S8e [rps8e]. 2 126 31.667 T 23-10-2018 IPR020919 Ribosomal protein S8e, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 TON_0354 158e501361632bdc03693e3be4b26e26 130 TIGRFAM TIGR00307 eS8: ribosomal protein eS8 1 127 7.5E-46 T 23-10-2018 IPR001047 Ribosomal protein S8e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0354 158e501361632bdc03693e3be4b26e26 130 Pfam PF01201 Ribosomal protein S8e 2 125 4.8E-32 T 23-10-2018 IPR022309 Ribosomal protein S8e/ribosomal biogenesis NSA2 TON_0354 158e501361632bdc03693e3be4b26e26 130 Gene3D G3DSA:2.40.10.310 61 130 1.4E-31 T 23-10-2018 TON_0403 09ed9a769b315095e79f1c3dbaeb1fd3 439 ProSitePatterns PS00917 Asparaginase / glutaminase active site signature 2. 172 182 - T 23-10-2018 IPR027475 Asparaginase/glutaminase, active site 2 Reactome: R-HSA-70614 TON_0403 09ed9a769b315095e79f1c3dbaeb1fd3 439 Pfam PF00710 Asparaginase, N-terminal 94 288 2.4E-62 T 23-10-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 TON_0403 09ed9a769b315095e79f1c3dbaeb1fd3 439 SUPERFAMILY SSF141300 4 76 4.84E-18 T 23-10-2018 IPR037222 GatD, N-terminal TON_0403 09ed9a769b315095e79f1c3dbaeb1fd3 439 Gene3D G3DSA:3.40.50.40 302 439 1.9E-57 T 23-10-2018 IPR027473 L-asparaginase, C-terminal Reactome: R-HSA-70614 TON_0403 09ed9a769b315095e79f1c3dbaeb1fd3 439 Gene3D G3DSA:3.40.50.1170 80 301 4.2E-86 T 23-10-2018 IPR037152 L-asparaginase, N-terminal domain superfamily Reactome: R-HSA-70614 TON_0403 09ed9a769b315095e79f1c3dbaeb1fd3 439 Hamap MF_00586 Glutamyl-tRNA(Gln) amidotransferase subunit D [gatD]. 19 433 49.05 T 23-10-2018 IPR011878 Glutamyl-tRNA(Gln) amidotransferase subunit D GO:0006450 TON_0403 09ed9a769b315095e79f1c3dbaeb1fd3 439 PRINTS PR00139 Asparaginase/glutaminase family signature 354 372 2.8E-19 T 23-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 TON_0403 09ed9a769b315095e79f1c3dbaeb1fd3 439 PRINTS PR00139 Asparaginase/glutaminase family signature 95 106 2.8E-19 T 23-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 TON_0403 09ed9a769b315095e79f1c3dbaeb1fd3 439 PRINTS PR00139 Asparaginase/glutaminase family signature 171 189 2.8E-19 T 23-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 TON_0403 09ed9a769b315095e79f1c3dbaeb1fd3 439 PIRSF PIRSF001220 89 428 2.0E-111 T 23-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 TON_0403 09ed9a769b315095e79f1c3dbaeb1fd3 439 SMART SM00870 94 417 7.6E-157 T 23-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 TON_0403 09ed9a769b315095e79f1c3dbaeb1fd3 439 PIRSF PIRSF500175 13 437 9.0E-191 T 23-10-2018 IPR011878 Glutamyl-tRNA(Gln) amidotransferase subunit D GO:0006450 TON_0403 09ed9a769b315095e79f1c3dbaeb1fd3 439 SUPERFAMILY SSF53774 87 436 4.97E-121 T 23-10-2018 IPR036152 Asparaginase/glutaminase-like superfamily Reactome: R-HSA-70614 TON_0403 09ed9a769b315095e79f1c3dbaeb1fd3 439 TIGRFAM TIGR02153 gatD_arch: glutamyl-tRNA(Gln) amidotransferase, subunit D 31 433 5.7E-197 T 23-10-2018 IPR011878 Glutamyl-tRNA(Gln) amidotransferase subunit D GO:0006450 TON_0403 09ed9a769b315095e79f1c3dbaeb1fd3 439 Gene3D G3DSA:2.30.30.520 2 79 3.5E-21 T 23-10-2018 IPR037222 GatD, N-terminal TON_0403 09ed9a769b315095e79f1c3dbaeb1fd3 439 TIGRFAM TIGR00519 asnASE_I: L-asparaginase, type I 92 429 6.8E-149 T 23-10-2018 IPR006033 L-asparaginase, type I GO:0004067|GO:0006520 Reactome: R-HSA-70614 TON_0403 09ed9a769b315095e79f1c3dbaeb1fd3 439 ProSitePatterns PS00144 Asparaginase / glutaminase active site signature 1. 97 105 - T 23-10-2018 IPR020827 Asparaginase/glutaminase, active site 1 GO:0006520 TON_1012 7e502ad185df186b5b8a94a3a799177e 459 PIRSF PIRSF015883 1 456 1.2E-203 T 23-10-2018 IPR015990 ADP-specific phosphofructokinase/glucokinase, archaeal GO:0000287|GO:0006096|GO:0016773 TON_1012 7e502ad185df186b5b8a94a3a799177e 459 Pfam PF04587 ADP-specific Phosphofructokinase/Glucokinase conserved region 11 447 3.5E-113 T 23-10-2018 IPR007666 ADP-specific phosphofructokinase/glucokinase GO:0005975|GO:0016773 Reactome: R-HSA-70171 TON_1012 7e502ad185df186b5b8a94a3a799177e 459 SUPERFAMILY SSF53613 10 455 2.94E-157 T 23-10-2018 IPR029056 Ribokinase-like TON_1012 7e502ad185df186b5b8a94a3a799177e 459 Gene3D G3DSA:3.40.1190.20 12 446 4.9E-161 T 23-10-2018 IPR029056 Ribokinase-like TON_1012 7e502ad185df186b5b8a94a3a799177e 459 Hamap MF_00561 ADP-specific phosphofructokinase [pfkC]. 4 456 44.485 T 23-10-2018 IPR011790 ADP-specific phosphofructokinase, archaeal GO:0005737|GO:0006000|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.146|KEGG: 00030+2.7.1.146|KEGG: 00680+2.7.1.146|MetaCyc: PWY-6142 TON_1012 7e502ad185df186b5b8a94a3a799177e 459 TIGRFAM TIGR02045 P_fruct_ADP: ADP-specific phosphofructokinase 11 456 1.5E-236 T 23-10-2018 IPR011790 ADP-specific phosphofructokinase, archaeal GO:0005737|GO:0006000|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.146|KEGG: 00030+2.7.1.146|KEGG: 00680+2.7.1.146|MetaCyc: PWY-6142 TON_1012 7e502ad185df186b5b8a94a3a799177e 459 Gene3D G3DSA:3.30.1110.20 18 198 4.9E-161 T 23-10-2018 TON_0178 1af6c7992a37cc6d426b4b8f6281d05d 152 TIGRFAM TIGR00405 KOW_elon_Spt5: transcription elongation factor Spt5 7 150 2.0E-52 T 23-10-2018 IPR011590 Transcription elongation factor Spt5, archaeal GO:0003746 TON_0178 1af6c7992a37cc6d426b4b8f6281d05d 152 Hamap MF_00950 Transcription elongation factor Spt5 [spt5]. 5 148 38.728 T 23-10-2018 IPR011590 Transcription elongation factor Spt5, archaeal GO:0003746 TON_0178 1af6c7992a37cc6d426b4b8f6281d05d 152 Gene3D G3DSA:3.30.70.940 3 87 4.7E-34 T 23-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 TON_0178 1af6c7992a37cc6d426b4b8f6281d05d 152 SMART SM00739 92 119 4.2E-7 T 23-10-2018 IPR005824 KOW TON_0178 1af6c7992a37cc6d426b4b8f6281d05d 152 Pfam PF03439 Early transcription elongation factor of RNA pol II, NGN section 5 84 5.6E-24 T 23-10-2018 IPR005100 NGN domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 TON_0178 1af6c7992a37cc6d426b4b8f6281d05d 152 Gene3D G3DSA:2.30.30.30 88 152 4.0E-28 T 23-10-2018 IPR014722 Ribosomal protein L2, domain 2 TON_0178 1af6c7992a37cc6d426b4b8f6281d05d 152 SMART SM00738 3 87 6.2E-21 T 23-10-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 TON_0178 1af6c7992a37cc6d426b4b8f6281d05d 152 Pfam PF00467 KOW motif 95 126 1.3E-8 T 23-10-2018 IPR005824 KOW TON_0178 1af6c7992a37cc6d426b4b8f6281d05d 152 SUPERFAMILY SSF50104 55 147 2.07E-17 T 23-10-2018 IPR008991 Translation protein SH3-like domain superfamily TON_0434 f5fe221667b1ccd34063a80f17e0fede 371 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 353 370 9.2E-30 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TON_0434 f5fe221667b1ccd34063a80f17e0fede 371 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 245 257 9.2E-30 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TON_0434 f5fe221667b1ccd34063a80f17e0fede 371 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 150 164 9.2E-30 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TON_0434 f5fe221667b1ccd34063a80f17e0fede 371 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 179 189 9.2E-30 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TON_0434 f5fe221667b1ccd34063a80f17e0fede 371 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 295 311 9.2E-30 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TON_0434 f5fe221667b1ccd34063a80f17e0fede 371 Pfam PF17125 N-terminal domain of 16S rRNA methyltransferase RsmF 74 164 2.5E-19 T 23-10-2018 IPR031341 Ribosomal RNA small subunit methyltransferase F, N-terminal Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 TON_0434 f5fe221667b1ccd34063a80f17e0fede 371 TIGRFAM TIGR00446 nop2p: NOL1/NOP2/sun family putative RNA methylase 104 370 5.1E-90 T 23-10-2018 IPR011023 Nop2p GO:0003723|GO:0006364|GO:0008757 Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 TON_0434 f5fe221667b1ccd34063a80f17e0fede 371 Gene3D G3DSA:3.40.50.150 165 371 6.8E-68 T 23-10-2018 TON_0434 f5fe221667b1ccd34063a80f17e0fede 371 SUPERFAMILY SSF53335 69 370 9.07E-76 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TON_0434 f5fe221667b1ccd34063a80f17e0fede 371 Pfam PF01189 16S rRNA methyltransferase RsmB/F 168 369 2.0E-58 T 23-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 TON_0434 f5fe221667b1ccd34063a80f17e0fede 371 ProSitePatterns PS01153 NOL1/NOP2/sun family signature. 244 255 - T 23-10-2018 IPR018314 Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site GO:0003723|GO:0008168 TON_0434 f5fe221667b1ccd34063a80f17e0fede 371 Gene3D G3DSA:3.30.70.3130 58 163 1.8E-34 T 23-10-2018 TON_1861 68a261f82fe99b0dcf6bb61c7d2bb06d 331 Gene3D G3DSA:3.90.550.10 2 216 1.3E-56 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TON_1861 68a261f82fe99b0dcf6bb61c7d2bb06d 331 SUPERFAMILY SSF53448 6 252 1.54E-57 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TON_1861 68a261f82fe99b0dcf6bb61c7d2bb06d 331 Pfam PF00535 Glycosyl transferase family 2 8 169 1.9E-32 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TON_0891 52e1c4fe789baaebedcf7f6c94ea7232 331 Gene3D G3DSA:3.30.2130.30 8 141 4.5E-6 T 23-10-2018 TON_0891 52e1c4fe789baaebedcf7f6c94ea7232 331 Gene3D G3DSA:3.40.50.150 153 331 2.3E-34 T 23-10-2018 TON_0891 52e1c4fe789baaebedcf7f6c94ea7232 331 Pfam PF02926 THUMP domain 59 133 1.6E-11 T 23-10-2018 IPR004114 THUMP domain GO:0003723 TON_0891 52e1c4fe789baaebedcf7f6c94ea7232 331 SUPERFAMILY SSF53335 34 307 1.44E-30 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TON_0891 52e1c4fe789baaebedcf7f6c94ea7232 331 SUPERFAMILY SSF143437 72 134 2.2E-5 T 23-10-2018 TON_0891 52e1c4fe789baaebedcf7f6c94ea7232 331 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 251 257 - T 23-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 TON_0891 52e1c4fe789baaebedcf7f6c94ea7232 331 TIGRFAM TIGR01177 TIGR01177: putative methyltransferase, TIGR01177 family 3 328 3.9E-99 T 23-10-2018 IPR005885 tRNA guanine(10)-N2-dimethyltransferase GO:0004809|GO:0030488 TON_0891 52e1c4fe789baaebedcf7f6c94ea7232 331 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 183 197 3.6E-7 T 23-10-2018 TON_0891 52e1c4fe789baaebedcf7f6c94ea7232 331 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 248 260 3.6E-7 T 23-10-2018 TON_0891 52e1c4fe789baaebedcf7f6c94ea7232 331 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 270 294 3.6E-7 T 23-10-2018 TON_0891 52e1c4fe789baaebedcf7f6c94ea7232 331 Pfam PF01170 Putative RNA methylase family UPF0020 156 306 5.8E-26 T 23-10-2018 IPR000241 Putative RNA methylase domain TON_0891 52e1c4fe789baaebedcf7f6c94ea7232 331 SMART SM00981 56 141 6.2E-6 T 23-10-2018 IPR004114 THUMP domain GO:0003723 TON_1791 3b503d4550b84d9b07542bd1ee471fe0 375 Gene3D G3DSA:2.40.50.100 245 307 1.5E-20 T 23-10-2018 TON_1791 3b503d4550b84d9b07542bd1ee471fe0 375 SUPERFAMILY SSF52540 5 248 2.52E-88 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_1791 3b503d4550b84d9b07542bd1ee471fe0 375 Gene3D G3DSA:2.40.50.140 313 357 1.3E-25 T 23-10-2018 TON_1791 3b503d4550b84d9b07542bd1ee471fe0 375 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TON_1791 3b503d4550b84d9b07542bd1ee471fe0 375 Pfam PF08402 TOBE domain 291 366 2.6E-7 T 23-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 TON_1791 3b503d4550b84d9b07542bd1ee471fe0 375 SMART SM00382 28 217 4.8E-14 T 23-10-2018 IPR003593 AAA+ ATPase domain TON_1791 3b503d4550b84d9b07542bd1ee471fe0 375 Pfam PF00005 ABC transporter 20 167 3.0E-32 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TON_1791 3b503d4550b84d9b07542bd1ee471fe0 375 SUPERFAMILY SSF50331 242 373 1.04E-24 T 23-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal TON_1791 3b503d4550b84d9b07542bd1ee471fe0 375 Gene3D G3DSA:3.40.50.300 1 243 1.4E-75 T 23-10-2018 TON_0941 ef5a56320be2747de1bb8f80624a9730 252 Gene3D G3DSA:3.20.20.140 1 251 2.5E-66 T 23-10-2018 TON_0941 ef5a56320be2747de1bb8f80624a9730 252 PIRSF PIRSF005902 1 252 1.2E-62 T 23-10-2018 IPR001130 TatD family GO:0016788 TON_0941 ef5a56320be2747de1bb8f80624a9730 252 TIGRFAM TIGR00010 TIGR00010: hydrolase, TatD family 1 249 2.0E-72 T 23-10-2018 IPR015991 Uncharacterised hydrolase TatD-type GO:0004536 TON_0941 ef5a56320be2747de1bb8f80624a9730 252 SUPERFAMILY SSF51556 2 250 2.42E-58 T 23-10-2018 IPR032466 Metal-dependent hydrolase TON_0941 ef5a56320be2747de1bb8f80624a9730 252 Pfam PF01026 TatD related DNase 2 248 8.8E-60 T 23-10-2018 IPR001130 TatD family GO:0016788 TON_1903 3f1eb37058231ac09dae0db6c9526539 363 SUPERFAMILY SSF52490 2 199 2.88E-40 T 23-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 TON_1903 3f1eb37058231ac09dae0db6c9526539 363 ProSitePatterns PS00227 Tubulin subunits alpha, beta, and gamma signature. 101 107 - T 23-10-2018 IPR017975 Tubulin, conserved site GO:0005525|GO:0005874|GO:0007017 Reactome: R-HSA-380320 TON_1903 3f1eb37058231ac09dae0db6c9526539 363 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 26 168 1.2E-25 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TON_1903 3f1eb37058231ac09dae0db6c9526539 363 PRINTS PR00423 Cell division protein FtsZ signature 93 113 5.9E-10 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TON_1903 3f1eb37058231ac09dae0db6c9526539 363 PRINTS PR00423 Cell division protein FtsZ signature 123 144 5.9E-10 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TON_1903 3f1eb37058231ac09dae0db6c9526539 363 PRINTS PR00423 Cell division protein FtsZ signature 183 205 5.9E-10 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TON_1903 3f1eb37058231ac09dae0db6c9526539 363 Hamap MF_01946 Tubulin-like protein CetZ [cetZ]. 1 354 26.548 T 23-10-2018 IPR032907 Tubulin-like protein CetZ GO:0008360 TON_1903 3f1eb37058231ac09dae0db6c9526539 363 Gene3D G3DSA:3.40.50.1440 2 362 1.7E-88 T 23-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 TON_1903 3f1eb37058231ac09dae0db6c9526539 363 SMART SM00864 2 199 4.6E-34 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TON_0867 e01985482a2b29410c68700c0c20bea2 53 SUPERFAMILY SSF57802 1 53 3.53E-25 T 23-10-2018 TON_0867 e01985482a2b29410c68700c0c20bea2 53 Gene3D G3DSA:2.20.28.10 2 53 1.2E-29 T 23-10-2018 TON_0867 e01985482a2b29410c68700c0c20bea2 53 ProSitePatterns PS00202 Rubredoxin signature. 33 43 - T 23-10-2018 IPR018527 Rubredoxin, iron-binding site GO:0046872 TON_0867 e01985482a2b29410c68700c0c20bea2 53 PIRSF PIRSF000071 1 53 2.3E-29 T 23-10-2018 IPR024922 Rubredoxin GO:0005506|GO:0009055 TON_0867 e01985482a2b29410c68700c0c20bea2 53 PRINTS PR00163 Rubredoxin signature 33 49 5.9E-12 T 23-10-2018 IPR024935 Rubredoxin domain GO:0005506 TON_0867 e01985482a2b29410c68700c0c20bea2 53 PRINTS PR00163 Rubredoxin signature 3 19 5.9E-12 T 23-10-2018 IPR024935 Rubredoxin domain GO:0005506 TON_0867 e01985482a2b29410c68700c0c20bea2 53 Pfam PF00301 Rubredoxin 3 49 9.1E-26 T 23-10-2018 IPR024935 Rubredoxin domain GO:0005506 TON_0085 5d87ca67e70105e9be01e6fd86673c50 201 SUPERFAMILY SSF53137 2 195 3.2E-63 T 23-10-2018 TON_0085 5d87ca67e70105e9be01e6fd86673c50 201 Pfam PF14204 Ribosomal L18 C-terminal region 143 194 9.6E-13 T 23-10-2018 IPR025607 Ribosomal protein L5 eukaryotic/L18 archaeal, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0085 5d87ca67e70105e9be01e6fd86673c50 201 PRINTS PR00058 Ribosomal protein L5 signature 123 142 4.5E-10 T 23-10-2018 IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0008097 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0085 5d87ca67e70105e9be01e6fd86673c50 201 PRINTS PR00058 Ribosomal protein L5 signature 1 12 4.5E-10 T 23-10-2018 IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0008097 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0085 5d87ca67e70105e9be01e6fd86673c50 201 PRINTS PR00058 Ribosomal protein L5 signature 103 122 4.5E-10 T 23-10-2018 IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0008097 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0085 5d87ca67e70105e9be01e6fd86673c50 201 Pfam PF17144 Ribosomal large subunit proteins 60S L5, and 50S L18 6 94 3.2E-14 T 23-10-2018 IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0008097 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0085 5d87ca67e70105e9be01e6fd86673c50 201 Pfam PF17144 Ribosomal large subunit proteins 60S L5, and 50S L18 101 134 6.9E-9 T 23-10-2018 IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0008097 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0085 5d87ca67e70105e9be01e6fd86673c50 201 Gene3D G3DSA:3.30.420.100 1 198 2.0E-72 T 23-10-2018 TON_0085 5d87ca67e70105e9be01e6fd86673c50 201 Hamap MF_01337_A 50S ribosomal protein L18 [rplR]. 5 192 44.419 T 23-10-2018 IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0008097 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0998 87bb36599138fae96940f4fb9de23981 202 Pfam PF02080 TrkA-C domain 125 190 6.4E-13 T 23-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 TON_0998 87bb36599138fae96940f4fb9de23981 202 Gene3D G3DSA:3.30.70.1450 117 202 5.7E-24 T 23-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 TON_0998 87bb36599138fae96940f4fb9de23981 202 Gene3D G3DSA:1.20.58.220 8 116 2.4E-22 T 23-10-2018 IPR038078 PhoU-like domain superfamily TON_0998 87bb36599138fae96940f4fb9de23981 202 Pfam PF01895 PhoU domain 19 100 1.3E-8 T 23-10-2018 IPR026022 PhoU domain TON_0998 87bb36599138fae96940f4fb9de23981 202 SUPERFAMILY SSF116726 108 191 2.75E-20 T 23-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 TON_0998 87bb36599138fae96940f4fb9de23981 202 SUPERFAMILY SSF109755 11 126 2.62E-16 T 23-10-2018 TON_1062 9a409d459a1de1bdc4ae19c74ddcffc1 503 ProSitePatterns PS00647 Thymidine and pyrimidine-nucleoside phosphorylases signature. 193 208 - T 23-10-2018 IPR017872 Pyrimidine-nucleoside phosphorylase, conserved site GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 TON_1062 9a409d459a1de1bdc4ae19c74ddcffc1 503 Gene3D G3DSA:2.40.40.20 1 83 1.9E-38 T 23-10-2018 TON_1062 9a409d459a1de1bdc4ae19c74ddcffc1 503 Pfam PF00591 Glycosyl transferase family, a/b domain 158 387 1.4E-15 T 23-10-2018 IPR000312 Glycosyl transferase, family 3 GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 TON_1062 9a409d459a1de1bdc4ae19c74ddcffc1 503 SMART SM00941 424 491 2.3E-25 T 23-10-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 TON_1062 9a409d459a1de1bdc4ae19c74ddcffc1 503 Hamap MF_02132 AMP phosphorylase. 1 503 47.097 T 23-10-2018 IPR017713 AMP phosphorylase GO:0009032|GO:0046125 MetaCyc: PWY-5532 TON_1062 9a409d459a1de1bdc4ae19c74ddcffc1 503 TIGRFAM TIGR03327 AMP_phos: AMP phosphorylase 3 500 8.3E-245 T 23-10-2018 IPR017713 AMP phosphorylase GO:0009032|GO:0046125 MetaCyc: PWY-5532 TON_1062 9a409d459a1de1bdc4ae19c74ddcffc1 503 Gene3D G3DSA:1.20.970.10 84 151 2.9E-24 T 23-10-2018 TON_1062 9a409d459a1de1bdc4ae19c74ddcffc1 503 TIGRFAM TIGR02645 ARCH_P_rylase: putative thymidine phosphorylase 4 494 1.6E-228 T 23-10-2018 IPR013466 Thymidine phosphorylase/AMP phosphorylase GO:0016763 TON_1062 9a409d459a1de1bdc4ae19c74ddcffc1 503 Gene3D G3DSA:3.40.1030.10 152 412 9.2E-102 T 23-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 TON_1062 9a409d459a1de1bdc4ae19c74ddcffc1 503 PIRSF PIRSF000478 84 502 2.9E-125 T 23-10-2018 IPR000053 Thymidine/pyrimidine-nucleoside phosphorylase GO:0004645|GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 TON_1062 9a409d459a1de1bdc4ae19c74ddcffc1 503 SUPERFAMILY SSF47648 86 153 1.16E-16 T 23-10-2018 IPR036320 Glycosyl transferase family 3, N-terminal domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 TON_1062 9a409d459a1de1bdc4ae19c74ddcffc1 503 Pfam PF07831 Pyrimidine nucleoside phosphorylase C-terminal domain 424 486 1.9E-15 T 23-10-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 TON_1062 9a409d459a1de1bdc4ae19c74ddcffc1 503 Pfam PF02885 Glycosyl transferase family, helical bundle domain 89 150 5.3E-15 T 23-10-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 TON_1062 9a409d459a1de1bdc4ae19c74ddcffc1 503 SUPERFAMILY SSF54680 412 495 4.71E-19 T 23-10-2018 IPR036566 Pyrimidine nucleoside phosphorylase-like, C-terminal domain superfamily GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 TON_1062 9a409d459a1de1bdc4ae19c74ddcffc1 503 Gene3D G3DSA:3.90.1170.30 413 493 1.0E-29 T 23-10-2018 IPR036566 Pyrimidine nucleoside phosphorylase-like, C-terminal domain superfamily GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 TON_1062 9a409d459a1de1bdc4ae19c74ddcffc1 503 SUPERFAMILY SSF52418 155 404 2.22E-69 T 23-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 TON_1296 374f69a765f64cccd0f861249cf85cdb 322 Gene3D G3DSA:1.20.120.420 1 114 3.1E-48 T 23-10-2018 IPR027363 Methylthioribose-1-phosphate isomerase, N-terminal KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 TON_1296 374f69a765f64cccd0f861249cf85cdb 322 Gene3D G3DSA:3.40.50.10470 115 310 1.5E-83 T 23-10-2018 TON_1296 374f69a765f64cccd0f861249cf85cdb 322 TIGRFAM TIGR00511 ribulose_e2b2: ribose-1,5-bisphosphate isomerase, e2b2 family 6 312 2.6E-146 T 23-10-2018 IPR005250 Ribose-1,5-bisphosphate isomerase, e2b2 family MetaCyc: PWY-5532 TON_1296 374f69a765f64cccd0f861249cf85cdb 322 Pfam PF01008 Initiation factor 2 subunit family 18 299 7.2E-92 T 23-10-2018 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 TON_1296 374f69a765f64cccd0f861249cf85cdb 322 SUPERFAMILY SSF100950 4 311 5.93E-100 T 23-10-2018 IPR037171 NagB/RpiA transferase-like TON_1296 374f69a765f64cccd0f861249cf85cdb 322 TIGRFAM TIGR00524 eIF-2B_rel: eIF-2B alpha/beta/delta-related uncharacterized proteins 5 299 1.7E-97 T 23-10-2018 IPR011559 Initiation factor 2B alpha/beta/delta GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 TON_0568 e5adf268955d84719e4e4f70e2977666 482 SMART SM00946 410 482 6.3E-26 T 23-10-2018 IPR016061 Proline-tRNA ligase, class II, C-terminal GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 TON_0568 e5adf268955d84719e4e4f70e2977666 482 Gene3D G3DSA:3.40.50.800 283 400 4.1E-36 T 23-10-2018 IPR036621 Anticodon-binding domain superfamily TON_0568 e5adf268955d84719e4e4f70e2977666 482 Pfam PF09180 Prolyl-tRNA synthetase, C-terminal 411 482 2.0E-16 T 23-10-2018 IPR016061 Proline-tRNA ligase, class II, C-terminal GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 TON_0568 e5adf268955d84719e4e4f70e2977666 482 Pfam PF03129 Anticodon binding domain 289 383 5.5E-22 T 23-10-2018 IPR004154 Anticodon-binding TON_0568 e5adf268955d84719e4e4f70e2977666 482 Gene3D G3DSA:3.30.930.10 11 282 2.3E-84 T 23-10-2018 TON_0568 e5adf268955d84719e4e4f70e2977666 482 PRINTS PR01046 Prolyl-tRNA synthetase signature 135 143 2.1E-12 T 23-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 TON_0568 e5adf268955d84719e4e4f70e2977666 482 PRINTS PR01046 Prolyl-tRNA synthetase signature 145 156 2.1E-12 T 23-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 TON_0568 e5adf268955d84719e4e4f70e2977666 482 PRINTS PR01046 Prolyl-tRNA synthetase signature 64 82 2.1E-12 T 23-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 TON_0568 e5adf268955d84719e4e4f70e2977666 482 PRINTS PR01046 Prolyl-tRNA synthetase signature 105 116 2.1E-12 T 23-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 TON_0568 e5adf268955d84719e4e4f70e2977666 482 TIGRFAM TIGR00408 proS_fam_I: proline--tRNA ligase 9 482 6.1E-178 T 23-10-2018 IPR004499 Proline-tRNA ligase, class IIa, archaeal-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 TON_0568 e5adf268955d84719e4e4f70e2977666 482 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 99 271 8.4E-23 T 23-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 TON_0568 e5adf268955d84719e4e4f70e2977666 482 SUPERFAMILY SSF52954 278 402 1.37E-35 T 23-10-2018 TON_0568 e5adf268955d84719e4e4f70e2977666 482 Hamap MF_01571 Proline--tRNA ligase [proS]. 5 482 40.979 T 23-10-2018 IPR004499 Proline-tRNA ligase, class IIa, archaeal-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 TON_0568 e5adf268955d84719e4e4f70e2977666 482 SUPERFAMILY SSF55681 10 276 4.4E-76 T 23-10-2018 TON_0568 e5adf268955d84719e4e4f70e2977666 482 SUPERFAMILY SSF64586 405 482 1.16E-21 T 23-10-2018 IPR017449 Prolyl-tRNA synthetase, class II GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 TON_0568 e5adf268955d84719e4e4f70e2977666 482 Gene3D G3DSA:3.30.110.30 404 481 1.3E-19 T 23-10-2018 IPR017449 Prolyl-tRNA synthetase, class II GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 TON_0956 df966c8971900ffa2987ddf63fa0077d 315 SUPERFAMILY SSF46785 261 313 1.88E-12 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TON_0956 df966c8971900ffa2987ddf63fa0077d 315 Pfam PF12802 MarR family 263 304 2.9E-9 T 23-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TON_0956 df966c8971900ffa2987ddf63fa0077d 315 Gene3D G3DSA:1.10.10.10 249 315 3.6E-12 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TON_1094 d6beb66c793fcbfd30c5c6476f4b9e7b 838 SMART SM01073 14 98 2.4E-36 T 23-10-2018 IPR003338 CDC48, N-terminal subdomain TON_1094 d6beb66c793fcbfd30c5c6476f4b9e7b 838 TIGRFAM TIGR01243 CDC48: AAA family ATPase, CDC48 subfamily 13 823 0.0 T 23-10-2018 IPR005938 AAA ATPase, CDC48 family GO:0016787 Reactome: R-HSA-110320|Reactome: R-HSA-3371511|Reactome: R-HSA-382556|Reactome: R-HSA-532668|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5678895|Reactome: R-HSA-5689877|Reactome: R-HSA-5689896|Reactome: R-HSA-6798695|Reactome: R-HSA-8866654|Reactome: R-HSA-8876725 TON_1094 d6beb66c793fcbfd30c5c6476f4b9e7b 838 Pfam PF02933 Cell division protein 48 (CDC48), domain 2 118 201 2.7E-14 T 23-10-2018 IPR004201 CDC48, domain 2 TON_1094 d6beb66c793fcbfd30c5c6476f4b9e7b 838 Gene3D G3DSA:1.10.8.60 715 823 7.4E-32 T 23-10-2018 TON_1094 d6beb66c793fcbfd30c5c6476f4b9e7b 838 SUPERFAMILY SSF54585 98 214 2.75E-18 T 23-10-2018 IPR029067 CDC48 domain 2-like superfamily TON_1094 d6beb66c793fcbfd30c5c6476f4b9e7b 838 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 249 378 5.0E-51 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TON_1094 d6beb66c793fcbfd30c5c6476f4b9e7b 838 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 584 713 1.1E-48 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TON_1094 d6beb66c793fcbfd30c5c6476f4b9e7b 838 Gene3D G3DSA:1.10.8.60 434 530 6.6E-16 T 23-10-2018 TON_1094 d6beb66c793fcbfd30c5c6476f4b9e7b 838 Pfam PF02359 Cell division protein 48 (CDC48), N-terminal domain 14 97 1.3E-29 T 23-10-2018 IPR003338 CDC48, N-terminal subdomain TON_1094 d6beb66c793fcbfd30c5c6476f4b9e7b 838 Gene3D G3DSA:3.40.50.300 538 713 1.8E-75 T 23-10-2018 TON_1094 d6beb66c793fcbfd30c5c6476f4b9e7b 838 Gene3D G3DSA:3.40.50.300 204 379 1.7E-74 T 23-10-2018 TON_1094 d6beb66c793fcbfd30c5c6476f4b9e7b 838 Gene3D G3DSA:1.10.8.60 380 417 6.5E-6 T 23-10-2018 TON_1094 d6beb66c793fcbfd30c5c6476f4b9e7b 838 ProSitePatterns PS00674 AAA-protein family signature. 349 367 - T 23-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 TON_1094 d6beb66c793fcbfd30c5c6476f4b9e7b 838 SUPERFAMILY SSF52540 207 529 6.58E-69 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_1094 d6beb66c793fcbfd30c5c6476f4b9e7b 838 SMART SM00382 245 381 8.2E-26 T 23-10-2018 IPR003593 AAA+ ATPase domain TON_1094 d6beb66c793fcbfd30c5c6476f4b9e7b 838 SMART SM00382 580 716 7.1E-24 T 23-10-2018 IPR003593 AAA+ ATPase domain TON_1094 d6beb66c793fcbfd30c5c6476f4b9e7b 838 SUPERFAMILY SSF52540 541 820 7.65E-80 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_1094 d6beb66c793fcbfd30c5c6476f4b9e7b 838 ProSitePatterns PS00674 AAA-protein family signature. 684 702 - T 23-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 TON_1094 d6beb66c793fcbfd30c5c6476f4b9e7b 838 SUPERFAMILY SSF50692 11 96 1.37E-26 T 23-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily TON_1094 d6beb66c793fcbfd30c5c6476f4b9e7b 838 Gene3D G3DSA:2.40.40.20 8 98 1.5E-32 T 23-10-2018 TON_1094 d6beb66c793fcbfd30c5c6476f4b9e7b 838 SMART SM01072 116 201 2.1E-17 T 23-10-2018 IPR004201 CDC48, domain 2 TON_0038 639a47b3c2cb1444cdaf83817f644144 375 TIGRFAM TIGR01109 Na_pump_decarbB: sodium ion-translocating decarboxylase, beta subunit 23 369 4.9E-158 T 23-10-2018 IPR005661 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit GO:0006814|GO:0016829 KEGG: 00620+4.1.1.3 TON_0038 639a47b3c2cb1444cdaf83817f644144 375 PIRSF PIRSF015658 1 375 8.2E-170 T 23-10-2018 IPR005661 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit GO:0006814|GO:0016829 KEGG: 00620+4.1.1.3 TON_0038 639a47b3c2cb1444cdaf83817f644144 375 Pfam PF03977 Na+-transporting oxaloacetate decarboxylase beta subunit 24 373 5.7E-158 T 23-10-2018 IPR005661 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit GO:0006814|GO:0016829 KEGG: 00620+4.1.1.3 TON_1498 cfa3904769586aca5b8f4e2ba5c35aae 653 SUPERFAMILY SSF56228 3 229 1.06E-45 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily TON_1498 cfa3904769586aca5b8f4e2ba5c35aae 653 Gene3D G3DSA:3.60.9.10 1 230 1.8E-26 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily TON_1498 cfa3904769586aca5b8f4e2ba5c35aae 653 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 272 576 1.9E-16 T 23-10-2018 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 TON_1498 cfa3904769586aca5b8f4e2ba5c35aae 653 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 4 226 6.8E-42 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 TON_1498 cfa3904769586aca5b8f4e2ba5c35aae 653 Gene3D G3DSA:1.10.569.10 281 475 5.9E-13 T 23-10-2018 IPR013984 Aldehyde ferredoxin oxidoreductase, domain 2 TON_1498 cfa3904769586aca5b8f4e2ba5c35aae 653 SUPERFAMILY SSF48310 254 651 3.27E-66 T 23-10-2018 IPR036021 Aldehyde ferredoxin oxidoreductase-like, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 TON_1498 cfa3904769586aca5b8f4e2ba5c35aae 653 SMART SM00790 1 227 2.4E-73 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 TON_0755 787f10ae6c0bc693d90eff24d1e6fde8 732 Gene3D G3DSA:3.30.70.240 466 718 3.7E-74 T 23-10-2018 TON_0755 787f10ae6c0bc693d90eff24d1e6fde8 732 Pfam PF03144 Elongation factor Tu domain 2 306 372 4.2E-15 T 23-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 TON_0755 787f10ae6c0bc693d90eff24d1e6fde8 732 Pfam PF00679 Elongation factor G C-terminus 621 704 7.2E-23 T 23-10-2018 IPR000640 Elongation factor EFG, domain V-like TON_0755 787f10ae6c0bc693d90eff24d1e6fde8 732 SUPERFAMILY SSF52540 10 261 3.3E-68 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_0755 787f10ae6c0bc693d90eff24d1e6fde8 732 SUPERFAMILY SSF54211 463 623 3.29E-48 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TON_0755 787f10ae6c0bc693d90eff24d1e6fde8 732 TIGRFAM TIGR00490 aEF-2: translation elongation factor aEF-2 3 720 0.0 T 23-10-2018 IPR004543 Translation elongation factor EFG/EF2, archaeal GO:0003746|GO:0005525|GO:0005737|GO:0006414 TON_0755 787f10ae6c0bc693d90eff24d1e6fde8 732 SMART SM00889 505 619 4.3E-19 T 23-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 TON_0755 787f10ae6c0bc693d90eff24d1e6fde8 732 Gene3D G3DSA:2.40.30.10 259 386 1.2E-27 T 23-10-2018 TON_0755 787f10ae6c0bc693d90eff24d1e6fde8 732 SUPERFAMILY SSF54980 388 463 1.15E-23 T 23-10-2018 IPR035647 EF-G domain III/V-like TON_0755 787f10ae6c0bc693d90eff24d1e6fde8 732 SUPERFAMILY SSF50447 259 373 8.25E-33 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily TON_0755 787f10ae6c0bc693d90eff24d1e6fde8 732 Gene3D G3DSA:3.30.70.870 388 465 8.6E-28 T 23-10-2018 TON_0755 787f10ae6c0bc693d90eff24d1e6fde8 732 Pfam PF00009 Elongation factor Tu GTP binding domain 20 257 2.5E-64 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TON_0755 787f10ae6c0bc693d90eff24d1e6fde8 732 Pfam PF03764 Elongation factor G, domain IV 513 618 9.4E-27 T 23-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 TON_0755 787f10ae6c0bc693d90eff24d1e6fde8 732 Pfam PF14492 Elongation Factor G, domain II 387 459 1.3E-26 T 23-10-2018 TON_0755 787f10ae6c0bc693d90eff24d1e6fde8 732 SUPERFAMILY SSF54980 624 717 4.03E-22 T 23-10-2018 IPR035647 EF-G domain III/V-like TON_0755 787f10ae6c0bc693d90eff24d1e6fde8 732 Hamap MF_00054_A Elongation factor G [fusA]. 2 725 43.694 T 23-10-2018 IPR004543 Translation elongation factor EFG/EF2, archaeal GO:0003746|GO:0005525|GO:0005737|GO:0006414 TON_0755 787f10ae6c0bc693d90eff24d1e6fde8 732 PRINTS PR00315 GTP-binding elongation factor signature 143 152 6.6E-16 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TON_0755 787f10ae6c0bc693d90eff24d1e6fde8 732 PRINTS PR00315 GTP-binding elongation factor signature 67 75 6.6E-16 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TON_0755 787f10ae6c0bc693d90eff24d1e6fde8 732 PRINTS PR00315 GTP-binding elongation factor signature 107 118 6.6E-16 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TON_0755 787f10ae6c0bc693d90eff24d1e6fde8 732 PRINTS PR00315 GTP-binding elongation factor signature 23 36 6.6E-16 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TON_0755 787f10ae6c0bc693d90eff24d1e6fde8 732 PRINTS PR00315 GTP-binding elongation factor signature 91 101 6.6E-16 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TON_0755 787f10ae6c0bc693d90eff24d1e6fde8 732 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 21 153 1.6E-20 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 TON_0755 787f10ae6c0bc693d90eff24d1e6fde8 732 SMART SM00838 621 708 8.4E-43 T 23-10-2018 IPR000640 Elongation factor EFG, domain V-like TON_0755 787f10ae6c0bc693d90eff24d1e6fde8 732 Gene3D G3DSA:3.40.50.300 7 222 2.5E-73 T 23-10-2018 TON_0755 787f10ae6c0bc693d90eff24d1e6fde8 732 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 60 75 - T 23-10-2018 IPR031157 Tr-type G domain, conserved site TON_0755 787f10ae6c0bc693d90eff24d1e6fde8 732 Gene3D G3DSA:3.30.230.10 472 720 3.7E-74 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TON_1583 4ae27280032375b774804e7742784aea 87 Pfam PF04066 Multiple resistance and pH regulation protein F (MrpF / PhaF) 31 82 1.0E-21 T 23-10-2018 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 TON_0152 09be77e072bd771904721ba392561ccc 649 SUPERFAMILY SSF46946 158 221 6.33E-7 T 23-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 TON_0152 09be77e072bd771904721ba392561ccc 649 Pfam PF05670 Domain of unknown function (DUF814) 454 552 2.0E-26 T 23-10-2018 IPR008532 Domain of unknown function DUF814 TON_0152 09be77e072bd771904721ba392561ccc 649 Gene3D G3DSA:2.30.310.10 5 150 1.6E-32 T 23-10-2018 TON_0152 09be77e072bd771904721ba392561ccc 649 Pfam PF05833 Fibronectin-binding protein A N-terminus (FbpA) 7 435 4.9E-86 T 23-10-2018 TON_0629 b2dc3c99a6e0b587c026c080c17751fa 134 Pfam PF01022 Bacterial regulatory protein, arsR family 60 106 4.8E-13 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TON_0629 b2dc3c99a6e0b587c026c080c17751fa 134 SMART SM00418 53 131 2.1E-10 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TON_0629 b2dc3c99a6e0b587c026c080c17751fa 134 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 87 102 3.6E-7 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TON_0629 b2dc3c99a6e0b587c026c080c17751fa 134 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 55 70 3.6E-7 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TON_0629 b2dc3c99a6e0b587c026c080c17751fa 134 SUPERFAMILY SSF46785 47 120 1.51E-17 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TON_0629 b2dc3c99a6e0b587c026c080c17751fa 134 Gene3D G3DSA:1.10.10.10 33 133 4.6E-19 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TON_0789 6b93e7a90264e097a065051ba4c15842 350 Pfam PF04055 Radical SAM superfamily 137 294 4.2E-19 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TON_0789 6b93e7a90264e097a065051ba4c15842 350 Pfam PF13353 4Fe-4S single cluster domain 135 224 1.5E-12 T 23-10-2018 TON_0789 6b93e7a90264e097a065051ba4c15842 350 PIRSF PIRSF004869 44 350 1.7E-72 T 23-10-2018 IPR016431 Pyruvate-formate lyase-activating enzyme, predicted TON_0789 6b93e7a90264e097a065051ba4c15842 350 SUPERFAMILY SSF102114 139 338 3.92E-25 T 23-10-2018 TON_0789 6b93e7a90264e097a065051ba4c15842 350 Gene3D G3DSA:3.20.20.70 131 347 1.1E-24 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TON_1858 e527c18cc1fcee52b5b91713b650afad 373 Gene3D G3DSA:3.40.50.2000 194 371 1.0E-49 T 23-10-2018 TON_1858 e527c18cc1fcee52b5b91713b650afad 373 Pfam PF00534 Glycosyl transferases group 1 197 349 1.7E-42 T 23-10-2018 IPR001296 Glycosyl transferase, family 1 TON_1858 e527c18cc1fcee52b5b91713b650afad 373 SUPERFAMILY SSF53756 2 371 4.57E-93 T 23-10-2018 TON_1858 e527c18cc1fcee52b5b91713b650afad 373 Pfam PF13439 Glycosyltransferase Family 4 16 184 2.3E-23 T 23-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 TON_1858 e527c18cc1fcee52b5b91713b650afad 373 Gene3D G3DSA:3.40.50.2000 1 193 5.0E-32 T 23-10-2018 TON_1944 de176910b4ccb43ecd49417bde63f22f 410 Gene3D G3DSA:3.40.50.300 3 203 3.4E-69 T 23-10-2018 TON_1944 de176910b4ccb43ecd49417bde63f22f 410 Pfam PF03144 Elongation factor Tu domain 2 231 311 1.1E-10 T 23-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 TON_1944 de176910b4ccb43ecd49417bde63f22f 410 Gene3D G3DSA:2.40.30.10 319 410 2.0E-34 T 23-10-2018 TON_1944 de176910b4ccb43ecd49417bde63f22f 410 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 10 193 1.1E-18 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 TON_1944 de176910b4ccb43ecd49417bde63f22f 410 PRINTS PR00315 GTP-binding elongation factor signature 13 26 4.1E-14 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TON_1944 de176910b4ccb43ecd49417bde63f22f 410 PRINTS PR00315 GTP-binding elongation factor signature 140 149 4.1E-14 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TON_1944 de176910b4ccb43ecd49417bde63f22f 410 PRINTS PR00315 GTP-binding elongation factor signature 103 114 4.1E-14 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TON_1944 de176910b4ccb43ecd49417bde63f22f 410 PRINTS PR00315 GTP-binding elongation factor signature 87 97 4.1E-14 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TON_1944 de176910b4ccb43ecd49417bde63f22f 410 SUPERFAMILY SSF52540 4 209 3.4E-54 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_1944 de176910b4ccb43ecd49417bde63f22f 410 Gene3D G3DSA:2.40.30.10 204 318 2.9E-47 T 23-10-2018 TON_1944 de176910b4ccb43ecd49417bde63f22f 410 SUPERFAMILY SSF50447 204 316 3.53E-38 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily TON_1944 de176910b4ccb43ecd49417bde63f22f 410 Pfam PF00009 Elongation factor Tu GTP binding domain 12 199 7.6E-37 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TON_1944 de176910b4ccb43ecd49417bde63f22f 410 Hamap MF_00119 Translation initiation factor 2 subunit gamma [eif2g]. 4 409 61.624 T 23-10-2018 IPR022424 Translation initiation factor 2, gamma subunit TON_1944 de176910b4ccb43ecd49417bde63f22f 410 TIGRFAM TIGR03680 eif2g_arch: translation initiation factor 2, gamma subunit 8 409 1.8E-207 T 23-10-2018 IPR022424 Translation initiation factor 2, gamma subunit TON_1944 de176910b4ccb43ecd49417bde63f22f 410 Pfam PF09173 Initiation factor eIF2 gamma, C terminal 324 408 4.3E-31 T 23-10-2018 IPR015256 Translation initiation factor 2, gamma subunit, C-terminal TON_1944 de176910b4ccb43ecd49417bde63f22f 410 SUPERFAMILY SSF50465 317 409 6.12E-33 T 23-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal TON_0428 264e9ed530241d78d1cb9afa29338afc 219 Hamap MF_00554 Ribosomal RNA small subunit methyltransferase Nep1 [nep1]. 2 216 40.43 T 23-10-2018 IPR023503 Ribosome biogenesis methyltransferase NEP1, archaea GO:0008168 TON_0428 264e9ed530241d78d1cb9afa29338afc 219 Gene3D G3DSA:3.40.1280.10 1 218 2.0E-76 T 23-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal TON_0428 264e9ed530241d78d1cb9afa29338afc 219 SUPERFAMILY SSF75217 1 217 2.01E-63 T 23-10-2018 IPR029028 Alpha/beta knot methyltransferases TON_0428 264e9ed530241d78d1cb9afa29338afc 219 Pfam PF03587 EMG1/NEP1 methyltransferase 5 215 1.3E-51 T 23-10-2018 IPR005304 Ribosomal biogenesis, methyltransferase, EMG1/NEP1 GO:0008168 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 TON_0557 b258163062b5b6bd44f814ed5c3d6539 211 Pfam PF13545 Crp-like helix-turn-helix domain 7 58 2.1E-8 T 23-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 TON_0557 b258163062b5b6bd44f814ed5c3d6539 211 SMART SM00419 14 66 0.0014 T 23-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 TON_0557 b258163062b5b6bd44f814ed5c3d6539 211 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 21 32 5.8E-5 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TON_0557 b258163062b5b6bd44f814ed5c3d6539 211 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 32 51 5.8E-5 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TON_0557 b258163062b5b6bd44f814ed5c3d6539 211 Gene3D G3DSA:1.10.10.10 1 83 2.2E-15 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TON_0557 b258163062b5b6bd44f814ed5c3d6539 211 SUPERFAMILY SSF82114 87 209 9.81E-39 T 23-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 TON_0557 b258163062b5b6bd44f814ed5c3d6539 211 Pfam PF01982 Domain of unknown function DUF120 92 209 1.3E-35 T 23-10-2018 IPR023602 Riboflavin kinase domain, CTP-dependent GO:0016773 KEGG: 00740+2.7.1.161|MetaCyc: PWY-6167 TON_0557 b258163062b5b6bd44f814ed5c3d6539 211 SUPERFAMILY SSF46785 4 80 2.49E-12 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TON_0557 b258163062b5b6bd44f814ed5c3d6539 211 Hamap MF_01285 Riboflavin kinase [ribK]. 86 209 24.288 T 23-10-2018 IPR023470 Riboflavin kinase, archaeal GO:0008531|GO:0009231 KEGG: 00740+2.7.1.161|MetaCyc: PWY-6167 TON_0557 b258163062b5b6bd44f814ed5c3d6539 211 Gene3D G3DSA:2.40.30.30 85 211 8.4E-39 T 23-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 TON_0238 dc4842648c32e5291831acf2089b1d1e 58 Gene3D G3DSA:2.20.28.40 1 58 3.8E-30 T 23-10-2018 IPR036756 H/ACA ribonucleoprotein complex, subunit Nop10 superfamily GO:0001522|GO:0030515|GO:0042254 Reactome: R-HSA-6790901 TON_0238 dc4842648c32e5291831acf2089b1d1e 58 SUPERFAMILY SSF144210 4 51 8.89E-22 T 23-10-2018 IPR036756 H/ACA ribonucleoprotein complex, subunit Nop10 superfamily GO:0001522|GO:0030515|GO:0042254 Reactome: R-HSA-6790901 TON_0238 dc4842648c32e5291831acf2089b1d1e 58 Pfam PF04135 Nucleolar RNA-binding protein, Nop10p family 1 51 1.7E-27 T 23-10-2018 IPR007264 H/ACA ribonucleoprotein complex, subunit Nop10 GO:0001522|GO:0030515|GO:0042254 Reactome: R-HSA-6790901 TON_0238 dc4842648c32e5291831acf2089b1d1e 58 Hamap MF_00803 Ribosome biogenesis protein Nop10 [nop10]. 3 53 21.183 T 23-10-2018 IPR023532 H/ACA ribonucleoprotein complex subunit Nop10 , archaeal-type GO:0001522|GO:0030515|GO:0042254 TON_0020 6b2a3e9fa75caccd3c42e9f37221cfdc 638 Gene3D G3DSA:3.40.50.970 11 202 4.6E-55 T 23-10-2018 TON_0020 6b2a3e9fa75caccd3c42e9f37221cfdc 638 Gene3D G3DSA:3.40.50.970 415 578 3.0E-23 T 23-10-2018 TON_0020 6b2a3e9fa75caccd3c42e9f37221cfdc 638 Pfam PF00037 4Fe-4S binding domain 607 630 5.5E-7 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TON_0020 6b2a3e9fa75caccd3c42e9f37221cfdc 638 TIGRFAM TIGR03336 IOR_alpha: indolepyruvate ferredoxin oxidoreductase, alpha subunit 25 629 3.7E-218 T 23-10-2018 IPR017721 Indolepyruvate ferredoxin oxidoreductase, alpha subunit GO:0043805|GO:0055114 TON_0020 6b2a3e9fa75caccd3c42e9f37221cfdc 638 Gene3D G3DSA:3.30.70.20 579 638 4.2E-11 T 23-10-2018 TON_0020 6b2a3e9fa75caccd3c42e9f37221cfdc 638 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 416 557 5.1E-32 T 23-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 TON_0020 6b2a3e9fa75caccd3c42e9f37221cfdc 638 SUPERFAMILY SSF52922 251 332 4.93E-7 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TON_0020 6b2a3e9fa75caccd3c42e9f37221cfdc 638 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 37 210 1.9E-14 T 23-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 TON_0020 6b2a3e9fa75caccd3c42e9f37221cfdc 638 SUPERFAMILY SSF52518 379 612 5.89E-36 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold TON_0020 6b2a3e9fa75caccd3c42e9f37221cfdc 638 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 614 625 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TON_0020 6b2a3e9fa75caccd3c42e9f37221cfdc 638 SUPERFAMILY SSF52518 24 258 1.18E-57 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold TON_0020 6b2a3e9fa75caccd3c42e9f37221cfdc 638 PIRSF PIRSF006439 14 635 9.1E-217 T 23-10-2018 IPR017721 Indolepyruvate ferredoxin oxidoreductase, alpha subunit GO:0043805|GO:0055114 TON_1324 302aad7369dfbc2ddba99aa5fa4c298f 382 Pfam PF00999 Sodium/hydrogen exchanger family 8 361 2.6E-29 T 23-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 TON_1324 302aad7369dfbc2ddba99aa5fa4c298f 382 Gene3D G3DSA:1.20.1530.20 2 378 7.8E-43 T 23-10-2018 IPR038770 Sodium/solute symporter superfamily TON_1687 7366ae13c4238340f6e3c23c0252b41d 499 SUPERFAMILY SSF55486 7 499 4.88E-113 T 23-10-2018 TON_1687 7366ae13c4238340f6e3c23c0252b41d 499 Gene3D G3DSA:1.10.1370.30 1 499 5.8E-198 T 23-10-2018 TON_1687 7366ae13c4238340f6e3c23c0252b41d 499 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 296 312 1.3E-86 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 TON_1687 7366ae13c4238340f6e3c23c0252b41d 499 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 336 355 1.3E-86 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 TON_1687 7366ae13c4238340f6e3c23c0252b41d 499 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 405 426 1.3E-86 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 TON_1687 7366ae13c4238340f6e3c23c0252b41d 499 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 269 288 1.3E-86 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 TON_1687 7366ae13c4238340f6e3c23c0252b41d 499 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 450 468 1.3E-86 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 TON_1687 7366ae13c4238340f6e3c23c0252b41d 499 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 249 268 1.3E-86 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 TON_1687 7366ae13c4238340f6e3c23c0252b41d 499 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 150 170 1.3E-86 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 TON_1687 7366ae13c4238340f6e3c23c0252b41d 499 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 232 248 1.3E-86 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 TON_1687 7366ae13c4238340f6e3c23c0252b41d 499 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 382 399 1.3E-86 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 TON_1687 7366ae13c4238340f6e3c23c0252b41d 499 PIRSF PIRSF006615 5 499 9.3E-199 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 TON_1687 7366ae13c4238340f6e3c23c0252b41d 499 Pfam PF02074 Carboxypeptidase Taq (M32) metallopeptidase 11 498 2.6E-108 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 TON_1817 8f7d66bb8f180a26848526bceafbe614 144 Pfam PF02915 Rubrerythrin 92 142 2.3E-6 T 23-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 TON_1817 8f7d66bb8f180a26848526bceafbe614 144 SUPERFAMILY SSF47240 2 142 3.16E-18 T 23-10-2018 IPR009078 Ferritin-like superfamily TON_1817 8f7d66bb8f180a26848526bceafbe614 144 Gene3D G3DSA:1.20.1260.10 1 144 5.6E-15 T 23-10-2018 IPR012347 Ferritin-like TON_1098 42211866734fc97f680cb077c85b13ec 141 Pfam PF06146 Phosphate-starvation-inducible E 66 132 9.9E-13 T 23-10-2018 IPR020948 Phosphate-starvation-induced PsiE-like TON_0695 c17c9c8355d78f596c281064e33c26b8 427 Gene3D G3DSA:3.40.50.12780 5 315 1.7E-28 T 23-10-2018 TON_0695 c17c9c8355d78f596c281064e33c26b8 427 SUPERFAMILY SSF56801 72 377 1.44E-25 T 23-10-2018 TON_0695 c17c9c8355d78f596c281064e33c26b8 427 ProSitePatterns PS00455 Putative AMP-binding domain signature. 81 92 - T 23-10-2018 IPR020845 AMP-binding, conserved site TON_0695 c17c9c8355d78f596c281064e33c26b8 427 Pfam PF00501 AMP-binding enzyme 73 238 1.5E-13 T 23-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 TON_0244 878006452467991f9e34d5ad232a7487 455 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 3 137 8.7E-47 T 23-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TON_0244 878006452467991f9e34d5ad232a7487 455 SUPERFAMILY SSF53738 156 259 2.04E-31 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TON_0244 878006452467991f9e34d5ad232a7487 455 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 236 251 1.0E-17 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TON_0244 878006452467991f9e34d5ad232a7487 455 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 208 221 1.0E-17 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TON_0244 878006452467991f9e34d5ad232a7487 455 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 94 108 1.0E-17 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TON_0244 878006452467991f9e34d5ad232a7487 455 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 174 193 1.0E-17 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TON_0244 878006452467991f9e34d5ad232a7487 455 Gene3D G3DSA:3.40.120.10 257 365 2.2E-77 T 23-10-2018 TON_0244 878006452467991f9e34d5ad232a7487 455 SUPERFAMILY SSF55957 358 454 1.12E-23 T 23-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TON_0244 878006452467991f9e34d5ad232a7487 455 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 156 256 9.3E-30 T 23-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TON_0244 878006452467991f9e34d5ad232a7487 455 SUPERFAMILY SSF53738 3 180 9.03E-47 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TON_0244 878006452467991f9e34d5ad232a7487 455 Gene3D G3DSA:3.40.120.10 1 152 1.3E-62 T 23-10-2018 TON_0244 878006452467991f9e34d5ad232a7487 455 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 261 369 2.0E-27 T 23-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TON_0244 878006452467991f9e34d5ad232a7487 455 Gene3D G3DSA:3.30.310.50 371 455 1.5E-31 T 23-10-2018 TON_0244 878006452467991f9e34d5ad232a7487 455 SUPERFAMILY SSF53738 261 367 1.37E-27 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TON_0244 878006452467991f9e34d5ad232a7487 455 Gene3D G3DSA:3.40.120.10 169 358 2.2E-77 T 23-10-2018 TON_0244 878006452467991f9e34d5ad232a7487 455 TIGRFAM TIGR03990 Arch_GlmM: phosphoglucosamine mutase 3 446 1.2E-178 T 23-10-2018 IPR024086 Phosphoglucosamine mutase, archaeal type GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TON_0244 878006452467991f9e34d5ad232a7487 455 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 383 444 3.7E-13 T 23-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TON_0308 29950f5312f577697e4fdbe19eb61f7b 1414 Pfam PF00082 Subtilase family 180 613 4.8E-59 T 23-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 TON_0308 29950f5312f577697e4fdbe19eb61f7b 1414 Gene3D G3DSA:3.40.50.200 171 280 1.1E-6 T 23-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 TON_0308 29950f5312f577697e4fdbe19eb61f7b 1414 Gene3D G3DSA:3.40.50.200 300 630 1.2E-68 T 23-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 TON_0308 29950f5312f577697e4fdbe19eb61f7b 1414 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 185 196 - T 23-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site TON_0308 29950f5312f577697e4fdbe19eb61f7b 1414 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 561 571 - T 23-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site TON_0308 29950f5312f577697e4fdbe19eb61f7b 1414 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 366 376 - T 23-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site TON_0308 29950f5312f577697e4fdbe19eb61f7b 1414 SUPERFAMILY SSF52743 175 623 6.15E-64 T 23-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 TON_0308 29950f5312f577697e4fdbe19eb61f7b 1414 PRINTS PR00723 Subtilisin serine protease family (S8) signature 560 576 3.8E-19 T 23-10-2018 IPR015500 Peptidase S8, subtilisin-related TON_0308 29950f5312f577697e4fdbe19eb61f7b 1414 PRINTS PR00723 Subtilisin serine protease family (S8) signature 180 199 3.8E-19 T 23-10-2018 IPR015500 Peptidase S8, subtilisin-related TON_0308 29950f5312f577697e4fdbe19eb61f7b 1414 PRINTS PR00723 Subtilisin serine protease family (S8) signature 362 375 3.8E-19 T 23-10-2018 IPR015500 Peptidase S8, subtilisin-related TON_1237 eba28aa3d927a704ffa249b142c32610 303 SUPERFAMILY SSF57783 5 50 1.05E-16 T 23-10-2018 TON_1237 eba28aa3d927a704ffa249b142c32610 303 ProSitePatterns PS00782 Transcription factor TFIIB repeat signature. 248 263 - T 23-10-2018 IPR023486 Transcription factor TFIIB, conserved site Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-674695|Reactome: R-HSA-6807505|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-76042 TON_1237 eba28aa3d927a704ffa249b142c32610 303 Gene3D G3DSA:1.10.472.170 6 202 6.8E-66 T 23-10-2018 TON_1237 eba28aa3d927a704ffa249b142c32610 303 Hamap MF_00383 Transcription initiation factor IIB [tfb]. 1 301 45.584 T 23-10-2018 IPR023484 Transcription initiation factor TFIIB, archaea TON_1237 eba28aa3d927a704ffa249b142c32610 303 PRINTS PR00685 Transcription initiation factor IIB signature 281 295 5.0E-58 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 TON_1237 eba28aa3d927a704ffa249b142c32610 303 PRINTS PR00685 Transcription initiation factor IIB signature 19 39 5.0E-58 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 TON_1237 eba28aa3d927a704ffa249b142c32610 303 PRINTS PR00685 Transcription initiation factor IIB signature 162 181 5.0E-58 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 TON_1237 eba28aa3d927a704ffa249b142c32610 303 PRINTS PR00685 Transcription initiation factor IIB signature 54 75 5.0E-58 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 TON_1237 eba28aa3d927a704ffa249b142c32610 303 PRINTS PR00685 Transcription initiation factor IIB signature 188 203 5.0E-58 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 TON_1237 eba28aa3d927a704ffa249b142c32610 303 PRINTS PR00685 Transcription initiation factor IIB signature 41 54 5.0E-58 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 TON_1237 eba28aa3d927a704ffa249b142c32610 303 PRINTS PR00685 Transcription initiation factor IIB signature 249 265 5.0E-58 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 TON_1237 eba28aa3d927a704ffa249b142c32610 303 PRINTS PR00685 Transcription initiation factor IIB signature 215 233 5.0E-58 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 TON_1237 eba28aa3d927a704ffa249b142c32610 303 SUPERFAMILY SSF47954 211 302 1.16E-29 T 23-10-2018 IPR036915 Cyclin-like superfamily TON_1237 eba28aa3d927a704ffa249b142c32610 303 Pfam PF08271 TFIIB zinc-binding 6 47 5.6E-18 T 23-10-2018 IPR013137 Zinc finger, TFIIB-type TON_1237 eba28aa3d927a704ffa249b142c32610 303 SUPERFAMILY SSF47954 114 207 7.73E-25 T 23-10-2018 IPR036915 Cyclin-like superfamily TON_1237 eba28aa3d927a704ffa249b142c32610 303 Pfam PF00382 Transcription factor TFIIB repeat 123 192 3.9E-19 T 23-10-2018 IPR013150 Transcription factor TFIIB, cyclin-like domain GO:0017025 TON_1237 eba28aa3d927a704ffa249b142c32610 303 Pfam PF00382 Transcription factor TFIIB repeat 216 286 1.2E-19 T 23-10-2018 IPR013150 Transcription factor TFIIB, cyclin-like domain GO:0017025 TON_1237 eba28aa3d927a704ffa249b142c32610 303 Gene3D G3DSA:1.10.472.10 211 303 1.1E-26 T 23-10-2018 TON_1237 eba28aa3d927a704ffa249b142c32610 303 ProSitePatterns PS00782 Transcription factor TFIIB repeat signature. 154 169 - T 23-10-2018 IPR023486 Transcription factor TFIIB, conserved site Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-674695|Reactome: R-HSA-6807505|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-76042 TON_1237 eba28aa3d927a704ffa249b142c32610 303 SMART SM00385 214 295 1.2E-10 T 23-10-2018 IPR013763 Cyclin-like TON_1237 eba28aa3d927a704ffa249b142c32610 303 SMART SM00385 120 201 9.0E-13 T 23-10-2018 IPR013763 Cyclin-like TON_0317 99eb700f8da25b4adea67a697ea6f00a 67 Pfam PF00037 4Fe-4S binding domain 7 30 4.1E-7 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TON_0317 99eb700f8da25b4adea67a697ea6f00a 67 Pfam PF00037 4Fe-4S binding domain 38 59 1.2E-8 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TON_0317 99eb700f8da25b4adea67a697ea6f00a 67 SUPERFAMILY SSF54862 7 63 7.33E-18 T 23-10-2018 TON_0317 99eb700f8da25b4adea67a697ea6f00a 67 Gene3D G3DSA:3.30.70.20 32 65 2.7E-7 T 23-10-2018 TON_0317 99eb700f8da25b4adea67a697ea6f00a 67 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 14 25 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TON_0317 99eb700f8da25b4adea67a697ea6f00a 67 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 43 54 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TON_0317 99eb700f8da25b4adea67a697ea6f00a 67 Gene3D G3DSA:3.30.70.20 1 31 2.4E-6 T 23-10-2018 TON_1158 85c0096c69c575c1ff1f1e7d2fcb3694 270 Gene3D G3DSA:3.40.630.30 4 180 5.3E-34 T 23-10-2018 TON_1158 85c0096c69c575c1ff1f1e7d2fcb3694 270 Pfam PF00583 Acetyltransferase (GNAT) family 25 126 3.4E-16 T 23-10-2018 IPR000182 GNAT domain TON_1158 85c0096c69c575c1ff1f1e7d2fcb3694 270 SUPERFAMILY SSF55729 1 133 2.83E-23 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase TON_0086 14ddee8677b7867b7081b1043ecb76aa 235 TIGRFAM TIGR01020 uS5_euk_arch: ribosomal protein uS5 10 221 1.2E-105 T 23-10-2018 IPR005711 Ribosomal protein S5, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-3214858|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8876725|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0086 14ddee8677b7867b7081b1043ecb76aa 235 Pfam PF03719 Ribosomal protein S5, C-terminal domain 145 210 6.5E-21 T 23-10-2018 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 TON_0086 14ddee8677b7867b7081b1043ecb76aa 235 Gene3D G3DSA:3.30.160.770 14 122 6.3E-37 T 23-10-2018 TON_0086 14ddee8677b7867b7081b1043ecb76aa 235 Hamap MF_01307_A 30S ribosomal protein S5 [rpsE]. 8 212 47.795 T 23-10-2018 IPR005711 Ribosomal protein S5, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-3214858|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8876725|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0086 14ddee8677b7867b7081b1043ecb76aa 235 SUPERFAMILY SSF54768 62 125 1.88E-18 T 23-10-2018 TON_0086 14ddee8677b7867b7081b1043ecb76aa 235 Gene3D G3DSA:3.30.230.10 123 214 1.7E-29 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TON_0086 14ddee8677b7867b7081b1043ecb76aa 235 ProSitePatterns PS00585 Ribosomal protein S5 signature. 77 109 - T 23-10-2018 IPR018192 Ribosomal protein S5, N-terminal, conserved site TON_0086 14ddee8677b7867b7081b1043ecb76aa 235 Pfam PF00333 Ribosomal protein S5, N-terminal domain 62 123 2.3E-21 T 23-10-2018 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 TON_0086 14ddee8677b7867b7081b1043ecb76aa 235 SUPERFAMILY SSF54211 138 210 5.06E-19 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TON_0786 7b1ed5a34397a6d9580d75749a471ea1 153 Pfam PF00578 AhpC/TSA family 10 128 2.0E-33 T 23-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 TON_0786 7b1ed5a34397a6d9580d75749a471ea1 153 PIRSF PIRSF000239 3 146 3.2E-25 T 23-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 TON_0786 7b1ed5a34397a6d9580d75749a471ea1 153 Gene3D G3DSA:3.40.30.10 2 150 2.3E-45 T 23-10-2018 TON_0786 7b1ed5a34397a6d9580d75749a471ea1 153 SUPERFAMILY SSF52833 9 149 5.7E-45 T 23-10-2018 IPR036249 Thioredoxin-like superfamily TON_0399 3814a48c45f560a5155de3678e1753ce 408 Gene3D G3DSA:3.30.70.420 129 244 5.0E-133 T 23-10-2018 IPR009023 Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain superfamily GO:0050662 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 TON_0399 3814a48c45f560a5155de3678e1753ce 408 Pfam PF00368 Hydroxymethylglutaryl-coenzyme A reductase 32 408 9.8E-141 T 23-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 TON_0399 3814a48c45f560a5155de3678e1753ce 408 SUPERFAMILY SSF56542 6 398 1.83E-93 T 23-10-2018 IPR009029 Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding domain superfamily GO:0015936|GO:0016616|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 TON_0399 3814a48c45f560a5155de3678e1753ce 408 Gene3D G3DSA:3.90.770.10 75 395 5.0E-133 T 23-10-2018 IPR023074 Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic domain superfamily GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 TON_0399 3814a48c45f560a5155de3678e1753ce 408 ProSitePatterns PS00066 Hydroxymethylglutaryl-coenzyme A reductases signature 1. 187 201 - T 23-10-2018 IPR023076 Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 TON_0399 3814a48c45f560a5155de3678e1753ce 408 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 64 85 4.3E-60 T 23-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 TON_0399 3814a48c45f560a5155de3678e1753ce 408 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 95 115 4.3E-60 T 23-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 TON_0399 3814a48c45f560a5155de3678e1753ce 408 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 276 302 4.3E-60 T 23-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 TON_0399 3814a48c45f560a5155de3678e1753ce 408 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 328 349 4.3E-60 T 23-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 TON_0399 3814a48c45f560a5155de3678e1753ce 408 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 185 203 4.3E-60 T 23-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 TON_0399 3814a48c45f560a5155de3678e1753ce 408 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 225 250 4.3E-60 T 23-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 TON_0399 3814a48c45f560a5155de3678e1753ce 408 TIGRFAM TIGR00533 HMG_CoA_R_NADP: hydroxymethylglutaryl-CoA reductase (NADPH) 2 408 1.2E-165 T 23-10-2018 IPR004554 Hydroxymethylglutaryl-CoA reductase, eukaryotic/archaeal type GO:0004420|GO:0008299|GO:0016021|GO:0050661|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 TON_0399 3814a48c45f560a5155de3678e1753ce 408 SUPERFAMILY SSF55035 129 244 1.44E-38 T 23-10-2018 IPR009023 Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain superfamily GO:0050662 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 TON_0399 3814a48c45f560a5155de3678e1753ce 408 Gene3D G3DSA:1.10.3270.10 1 74 1.2E-6 T 23-10-2018 IPR023282 Hydroxymethylglutaryl-CoA reductase, N-terminal GO:0004420 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 TON_0399 3814a48c45f560a5155de3678e1753ce 408 ProSitePatterns PS00318 Hydroxymethylglutaryl-coenzyme A reductases signature 2. 340 347 - T 23-10-2018 IPR023076 Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 TON_0743 7608afe267889324f1b33e1a9986e0c4 432 Hamap MF_01908 Cyclic 2,3-diphosphoglycerate synthetase [cpgS]. 1 432 50.381 T 23-10-2018 IPR016557 Cyclic 2, 3-diphospoglycerate synthetase GO:0005737|GO:0006094|GO:0036356 TON_0743 7608afe267889324f1b33e1a9986e0c4 432 Gene3D G3DSA:3.40.50.300 181 317 7.1E-6 T 23-10-2018 TON_0743 7608afe267889324f1b33e1a9986e0c4 432 PIRSF PIRSF009445 1 432 3.0E-196 T 23-10-2018 IPR016557 Cyclic 2, 3-diphospoglycerate synthetase GO:0005737|GO:0006094|GO:0036356 TON_0252 118fe9ec5a4bd55bf423cf2886bcbc29 311 SMART SM00849 19 207 1.0E-4 T 23-10-2018 IPR001279 Metallo-beta-lactamase TON_0252 118fe9ec5a4bd55bf423cf2886bcbc29 311 TIGRFAM TIGR02651 RNase_Z: ribonuclease Z 3 292 3.2E-99 T 23-10-2018 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 TON_0252 118fe9ec5a4bd55bf423cf2886bcbc29 311 Pfam PF00753 Metallo-beta-lactamase superfamily 18 76 9.6E-9 T 23-10-2018 IPR001279 Metallo-beta-lactamase TON_0252 118fe9ec5a4bd55bf423cf2886bcbc29 311 Pfam PF12706 Beta-lactamase superfamily domain 197 263 9.6E-9 T 23-10-2018 IPR001279 Metallo-beta-lactamase TON_0252 118fe9ec5a4bd55bf423cf2886bcbc29 311 Hamap MF_01818 Ribonuclease BN [rbn]. 2 296 34.575 T 23-10-2018 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 TON_0252 118fe9ec5a4bd55bf423cf2886bcbc29 311 Gene3D G3DSA:3.60.15.10 1 296 5.2E-84 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TON_0252 118fe9ec5a4bd55bf423cf2886bcbc29 311 SUPERFAMILY SSF56281 3 296 1.77E-73 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TON_1890 6404fc9c5125a2fb838209c7901c5b0d 335 Pfam PF05690 Thiazole biosynthesis protein ThiG 245 299 1.6E-7 T 23-10-2018 IPR033983 Thiazole synthase ThiG KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 TON_1890 6404fc9c5125a2fb838209c7901c5b0d 335 ProSitePatterns PS01235 PdxS/SNZ family signature. 248 266 - T 23-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 TON_1890 6404fc9c5125a2fb838209c7901c5b0d 335 Pfam PF01680 SOR/SNZ family 13 213 1.4E-95 T 23-10-2018 IPR033755 PdxS/SNZ N-terminal domain KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 TON_1890 6404fc9c5125a2fb838209c7901c5b0d 335 PIRSF PIRSF029271 3 335 1.1E-147 T 23-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 TON_1890 6404fc9c5125a2fb838209c7901c5b0d 335 Hamap MF_01824 Pyridoxal 5'-phosphate synthase subunit PdxS [pdxS]. 10 335 53.438 T 23-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 TON_1890 6404fc9c5125a2fb838209c7901c5b0d 335 SUPERFAMILY SSF51366 24 312 7.06E-60 T 23-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 TON_1890 6404fc9c5125a2fb838209c7901c5b0d 335 TIGRFAM TIGR00343 TIGR00343: pyridoxal 5'-phosphate synthase, synthase subunit Pdx1 15 334 7.7E-146 T 23-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 TON_1890 6404fc9c5125a2fb838209c7901c5b0d 335 Gene3D G3DSA:3.20.20.70 1 316 3.2E-152 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TON_1255 658f06a743c07b176f1f2cfd4879786b 256 Pfam PF13614 AAA domain 4 178 2.4E-54 T 23-10-2018 IPR025669 AAA domain TON_1255 658f06a743c07b176f1f2cfd4879786b 256 Gene3D G3DSA:3.40.50.300 1 255 4.7E-73 T 23-10-2018 TON_1255 658f06a743c07b176f1f2cfd4879786b 256 SUPERFAMILY SSF52540 1 254 1.21E-59 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_1343 3f66ed24f3829bd48b2dbe09393c0393 726 Gene3D G3DSA:1.10.150.20 661 695 6.8E-5 T 23-10-2018 TON_1343 3f66ed24f3829bd48b2dbe09393c0393 726 Gene3D G3DSA:1.10.3380.20 492 660 3.3E-58 T 23-10-2018 TON_1343 3f66ed24f3829bd48b2dbe09393c0393 726 SMART SM00490 288 374 1.5E-16 T 23-10-2018 IPR001650 Helicase, C-terminal TON_1343 3f66ed24f3829bd48b2dbe09393c0393 726 Gene3D G3DSA:1.10.10.10 408 491 8.0E-30 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TON_1343 3f66ed24f3829bd48b2dbe09393c0393 726 SMART SM00278 678 697 12.0 T 23-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 TON_1343 3f66ed24f3829bd48b2dbe09393c0393 726 SMART SM00278 645 664 0.59 T 23-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 TON_1343 3f66ed24f3829bd48b2dbe09393c0393 726 Hamap MF_00442 ATP-dependent DNA helicase Hel308 [hel308]. 9 700 30.636 T 23-10-2018 IPR022965 ATP-dependent DNA helicase Hel308 GO:0004386 TON_1343 3f66ed24f3829bd48b2dbe09393c0393 726 Pfam PF00271 Helicase conserved C-terminal domain 233 373 7.1E-11 T 23-10-2018 IPR001650 Helicase, C-terminal TON_1343 3f66ed24f3829bd48b2dbe09393c0393 726 SUPERFAMILY SSF52540 196 393 7.78E-40 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_1343 3f66ed24f3829bd48b2dbe09393c0393 726 SMART SM00487 20 204 4.8E-30 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TON_1343 3f66ed24f3829bd48b2dbe09393c0393 726 SUPERFAMILY SSF46785 405 492 1.93E-15 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TON_1343 3f66ed24f3829bd48b2dbe09393c0393 726 SUPERFAMILY SSF158702 493 701 1.91E-60 T 23-10-2018 TON_1343 3f66ed24f3829bd48b2dbe09393c0393 726 Gene3D G3DSA:3.40.50.300 201 399 1.3E-62 T 23-10-2018 TON_1343 3f66ed24f3829bd48b2dbe09393c0393 726 SUPERFAMILY SSF52540 2 192 7.81E-47 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_1343 3f66ed24f3829bd48b2dbe09393c0393 726 Gene3D G3DSA:3.40.50.300 8 200 3.7E-74 T 23-10-2018 TON_1343 3f66ed24f3829bd48b2dbe09393c0393 726 Pfam PF00270 DEAD/DEAH box helicase 26 180 4.5E-25 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 TON_1343 3f66ed24f3829bd48b2dbe09393c0393 726 Pfam PF14520 Helix-hairpin-helix domain 646 692 3.7E-10 T 23-10-2018 TON_1065 42ea3e04c532acf7eef5c94a5b402a5d 255 Pfam PF01884 PcrB family 17 240 1.3E-67 T 23-10-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 TON_1065 42ea3e04c532acf7eef5c94a5b402a5d 255 TIGRFAM TIGR01769 GGGP: phosphoglycerol geranylgeranyltransferase 22 230 3.1E-84 T 23-10-2018 IPR010946 Geranylgeranylglyceryl phosphate synthase GO:0000287|GO:0005737|GO:0006650|GO:0047294 KEGG: 00564+2.5.1.41|MetaCyc: PWY-6349 TON_1065 42ea3e04c532acf7eef5c94a5b402a5d 255 TIGRFAM TIGR01768 GGGP-family: geranylgeranylglyceryl phosphate synthase family protein 21 237 7.4E-78 T 23-10-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 TON_1065 42ea3e04c532acf7eef5c94a5b402a5d 255 SUPERFAMILY SSF51395 19 239 2.64E-48 T 23-10-2018 TON_1065 42ea3e04c532acf7eef5c94a5b402a5d 255 Gene3D G3DSA:3.20.20.390 3 255 5.8E-100 T 23-10-2018 IPR038597 GGGP/HepGP synthase superfamily TON_1065 42ea3e04c532acf7eef5c94a5b402a5d 255 Hamap MF_00112 Geranylgeranylglyceryl phosphate synthase [pcrB]. 15 252 36.04 T 23-10-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 TON_0243 a556ed022398dbbaea35905684398a1c 266 TIGRFAM TIGR01166 cbiO: cobalt ABC transporter, ATP-binding protein 14 194 3.0E-67 T 23-10-2018 IPR005876 Cobalt transport protein ATP-binding subunit GO:0006824 TON_0243 a556ed022398dbbaea35905684398a1c 266 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TON_0243 a556ed022398dbbaea35905684398a1c 266 Gene3D G3DSA:3.40.50.300 1 261 1.7E-73 T 23-10-2018 TON_0243 a556ed022398dbbaea35905684398a1c 266 SMART SM00382 26 217 6.8E-13 T 23-10-2018 IPR003593 AAA+ ATPase domain TON_0243 a556ed022398dbbaea35905684398a1c 266 SUPERFAMILY SSF52540 1 225 1.33E-63 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_0243 a556ed022398dbbaea35905684398a1c 266 Pfam PF00005 ABC transporter 17 162 1.5E-29 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TON_0783 c6d9bfdec44add749046946cf96a4c60 752 Pfam PF00582 Universal stress protein family 476 606 2.6E-20 T 23-10-2018 IPR006016 UspA TON_0783 c6d9bfdec44add749046946cf96a4c60 752 Pfam PF00582 Universal stress protein family 685 734 1.1E-7 T 23-10-2018 IPR006016 UspA TON_0783 c6d9bfdec44add749046946cf96a4c60 752 SUPERFAMILY SSF52402 476 608 7.67E-22 T 23-10-2018 TON_0783 c6d9bfdec44add749046946cf96a4c60 752 Gene3D G3DSA:3.40.50.620 467 606 1.2E-19 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TON_0783 c6d9bfdec44add749046946cf96a4c60 752 PRINTS PR01438 Universal stress protein signature 566 578 3.3E-6 T 23-10-2018 IPR006015 Universal stress protein A TON_0783 c6d9bfdec44add749046946cf96a4c60 752 PRINTS PR01438 Universal stress protein signature 584 606 3.3E-6 T 23-10-2018 IPR006015 Universal stress protein A TON_0783 c6d9bfdec44add749046946cf96a4c60 752 Gene3D G3DSA:1.20.1740.10 9 466 5.4E-103 T 23-10-2018 TON_0783 c6d9bfdec44add749046946cf96a4c60 752 Pfam PF13520 Amino acid permease 14 444 5.5E-51 T 23-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 TON_0783 c6d9bfdec44add749046946cf96a4c60 752 SUPERFAMILY SSF52402 616 735 2.15E-17 T 23-10-2018 TON_0783 c6d9bfdec44add749046946cf96a4c60 752 Gene3D G3DSA:3.40.50.620 614 735 9.8E-16 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TON_0776 a1bbfcee61f14c6faf6b02a104d6ab6b 64 Gene3D G3DSA:3.90.1530.10 1 46 5.4E-7 T 23-10-2018 TON_0776 a1bbfcee61f14c6faf6b02a104d6ab6b 64 SUPERFAMILY SSF110849 1 38 1.28E-9 T 23-10-2018 IPR036086 ParB/Sulfiredoxin superfamily TON_0776 a1bbfcee61f14c6faf6b02a104d6ab6b 64 Pfam PF02195 ParB-like nuclease domain 6 34 1.7E-5 T 23-10-2018 IPR003115 ParB/Sulfiredoxin TON_1505 930f457c0c583853ba456968579bdb5c 568 SUPERFAMILY SSF88697 512 566 4.41E-13 T 23-10-2018 IPR015947 PUA-like superfamily TON_1505 930f457c0c583853ba456968579bdb5c 568 SUPERFAMILY SSF52141 265 421 7.19E-42 T 23-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 TON_1505 930f457c0c583853ba456968579bdb5c 568 Pfam PF01472 PUA domain 513 566 3.1E-11 T 23-10-2018 IPR002478 PUA domain GO:0003723 TON_1505 930f457c0c583853ba456968579bdb5c 568 Gene3D G3DSA:2.30.130.10 502 568 1.2E-24 T 23-10-2018 IPR036974 PUA domain superfamily GO:0003723 TON_1505 930f457c0c583853ba456968579bdb5c 568 SUPERFAMILY SSF88802 247 499 4.38E-15 T 23-10-2018 TON_1505 930f457c0c583853ba456968579bdb5c 568 SMART SM00359 502 568 4.1E-9 T 23-10-2018 IPR002478 PUA domain GO:0003723 TON_1505 930f457c0c583853ba456968579bdb5c 568 SUPERFAMILY SSF51713 1 243 1.12E-20 T 23-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 TON_1505 930f457c0c583853ba456968579bdb5c 568 TIGRFAM TIGR00451 unchar_dom_2: uncharacterized domain 2 511 565 1.2E-9 T 23-10-2018 IPR004521 Uncharacterised domain CHP00451 GO:0003723 TON_1505 930f457c0c583853ba456968579bdb5c 568 Gene3D G3DSA:3.40.50.10630 252 423 2.7E-48 T 23-10-2018 TON_0709 96a323d061fa9574f9c149fae940da7c 220 Pfam PF01163 RIO1 family 48 147 7.1E-15 T 23-10-2018 TON_0709 96a323d061fa9574f9c149fae940da7c 220 SMART SM00220 1 219 1.6E-4 T 23-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TON_0709 96a323d061fa9574f9c149fae940da7c 220 SUPERFAMILY SSF56112 2 157 5.66E-29 T 23-10-2018 IPR011009 Protein kinase-like domain superfamily TON_0709 96a323d061fa9574f9c149fae940da7c 220 Gene3D G3DSA:3.30.200.20 15 88 5.8E-27 T 23-10-2018 TON_0709 96a323d061fa9574f9c149fae940da7c 220 Gene3D G3DSA:1.10.510.10 96 215 3.5E-33 T 23-10-2018 TON_0709 96a323d061fa9574f9c149fae940da7c 220 ProSitePatterns PS00109 Tyrosine protein kinases specific active-site signature. 124 136 - T 23-10-2018 IPR008266 Tyrosine-protein kinase, active site GO:0004672|GO:0006468 TON_0709 96a323d061fa9574f9c149fae940da7c 220 TIGRFAM TIGR03724 arch_bud32: Kae1-associated kinase Bud32 3 213 4.7E-74 T 23-10-2018 IPR022495 Serine/threonine-protein kinase Bud32 GO:0004674 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6782315|Reactome: R-HSA-6804756 TON_1784 0bd45f5632215b5619a28511391d8b9d 247 Gene3D G3DSA:3.40.50.150 66 247 7.3E-39 T 23-10-2018 TON_1784 0bd45f5632215b5619a28511391d8b9d 247 Pfam PF05971 Protein of unknown function (DUF890) 18 164 3.4E-9 T 23-10-2018 IPR010286 Ribosomal RNA large subunit methyltransferase F-like GO:0008168 TON_1784 0bd45f5632215b5619a28511391d8b9d 247 SUPERFAMILY SSF53335 14 232 4.49E-23 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TON_0565 9b456be39af0908b7df8b6b3e77da594 389 Pfam PF00155 Aminotransferase class I and II 28 378 4.7E-74 T 23-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 TON_0565 9b456be39af0908b7df8b6b3e77da594 389 Gene3D G3DSA:3.40.640.10 58 280 5.7E-150 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TON_0565 9b456be39af0908b7df8b6b3e77da594 389 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 230 243 - T 23-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 TON_0565 9b456be39af0908b7df8b6b3e77da594 389 SUPERFAMILY SSF53383 2 385 6.66E-122 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TON_0565 9b456be39af0908b7df8b6b3e77da594 389 Gene3D G3DSA:3.90.1150.10 29 378 5.7E-150 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TON_1765 ec2a05267c091303821f98ff17a17ddb 347 SUPERFAMILY SSF161098 119 323 7.33E-16 T 23-10-2018 IPR035906 MetI-like superfamily TON_1765 ec2a05267c091303821f98ff17a17ddb 347 Gene3D G3DSA:1.10.3720.10 114 336 1.3E-17 T 23-10-2018 IPR035906 MetI-like superfamily TON_1765 ec2a05267c091303821f98ff17a17ddb 347 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 141 340 1.1E-35 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TON_1636 4e7da1d3758482b4420b2592a72c83c1 438 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 146 283 3.3E-56 T 23-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain TON_1636 4e7da1d3758482b4420b2592a72c83c1 438 SUPERFAMILY SSF52210 290 437 1.44E-39 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TON_1636 4e7da1d3758482b4420b2592a72c83c1 438 SUPERFAMILY SSF52210 128 283 1.57E-42 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TON_1636 4e7da1d3758482b4420b2592a72c83c1 438 Gene3D G3DSA:3.40.50.261 288 438 2.0E-53 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TON_1636 4e7da1d3758482b4420b2592a72c83c1 438 Pfam PF13380 CoA binding domain 8 129 9.1E-18 T 23-10-2018 IPR003781 CoA-binding GO:0048037 TON_1636 4e7da1d3758482b4420b2592a72c83c1 438 SUPERFAMILY SSF51735 2 126 4.22E-23 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TON_1636 4e7da1d3758482b4420b2592a72c83c1 438 Gene3D G3DSA:3.40.50.720 1 125 2.4E-30 T 23-10-2018 TON_1636 4e7da1d3758482b4420b2592a72c83c1 438 SMART SM00881 4 98 6.8E-22 T 23-10-2018 IPR003781 CoA-binding GO:0048037 TON_1636 4e7da1d3758482b4420b2592a72c83c1 438 Gene3D G3DSA:3.40.50.261 135 286 4.0E-59 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TON_1243 9b448024cf97a77ba0070ca16ca783d7 253 SMART SM00382 26 209 3.0E-14 T 23-10-2018 IPR003593 AAA+ ATPase domain TON_1243 9b448024cf97a77ba0070ca16ca783d7 253 SUPERFAMILY SSF52540 1 221 5.74E-64 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_1243 9b448024cf97a77ba0070ca16ca783d7 253 Gene3D G3DSA:3.40.50.300 1 242 7.8E-70 T 23-10-2018 TON_1243 9b448024cf97a77ba0070ca16ca783d7 253 Pfam PF00005 ABC transporter 17 161 4.1E-28 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TON_0894 9015c43e69a4d2c7bcead780832634f9 186 TIGRFAM TIGR01870 cas_TM1810_Csm2: CRISPR type III-A/MTUBE-associated protein Csm2 90 183 3.0E-18 T 23-10-2018 IPR010149 CRISPR-associated protein, Csm2 Type III-A TON_0894 9015c43e69a4d2c7bcead780832634f9 186 Pfam PF03750 Csm2 Type III-A 76 184 7.5E-18 T 23-10-2018 IPR010149 CRISPR-associated protein, Csm2 Type III-A TON_1428 deb61cb4d81490d6e7a8567cffa41636 377 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 55 347 6.9E-73 T 23-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme TON_1428 deb61cb4d81490d6e7a8567cffa41636 377 TIGRFAM TIGR00260 thrC: threonine synthase 41 352 3.5E-56 T 23-10-2018 IPR004450 Threonine synthase-like TON_1428 deb61cb4d81490d6e7a8567cffa41636 377 Gene3D G3DSA:3.40.50.1100 89 184 3.4E-108 T 23-10-2018 TON_1428 deb61cb4d81490d6e7a8567cffa41636 377 SUPERFAMILY SSF53686 22 357 1.07E-87 T 23-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme TON_1428 deb61cb4d81490d6e7a8567cffa41636 377 Gene3D G3DSA:3.40.50.1100 41 352 3.4E-108 T 23-10-2018 TON_0315 7e70290494981634a36fff807bb263dd 717 Gene3D G3DSA:1.10.290.10 279 406 2.0E-123 T 23-10-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 TON_0315 7e70290494981634a36fff807bb263dd 717 Pfam PF01131 DNA topoisomerase 156 564 1.2E-132 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 TON_0315 7e70290494981634a36fff807bb263dd 717 Pfam PF01751 Toprim domain 3 139 3.8E-18 T 23-10-2018 IPR006171 TOPRIM domain TON_0315 7e70290494981634a36fff807bb263dd 717 Gene3D G3DSA:3.40.50.140 1 154 2.2E-30 T 23-10-2018 TON_0315 7e70290494981634a36fff807bb263dd 717 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 313 322 7.1E-26 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 TON_0315 7e70290494981634a36fff807bb263dd 717 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 392 408 7.1E-26 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 TON_0315 7e70290494981634a36fff807bb263dd 717 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 103 116 7.1E-26 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 TON_0315 7e70290494981634a36fff807bb263dd 717 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 491 505 7.1E-26 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 TON_0315 7e70290494981634a36fff807bb263dd 717 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 196 214 7.1E-26 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 TON_0315 7e70290494981634a36fff807bb263dd 717 TIGRFAM TIGR01057 topA_arch: DNA topoisomerase I 6 666 7.4E-285 T 23-10-2018 IPR005739 DNA topoisomerase I, archeal-type GO:0003677|GO:0003916|GO:0006265 TON_0315 7e70290494981634a36fff807bb263dd 717 SMART SM00437 271 527 2.7E-103 T 23-10-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 TON_0315 7e70290494981634a36fff807bb263dd 717 SMART SM00436 131 226 9.1E-43 T 23-10-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 TON_0315 7e70290494981634a36fff807bb263dd 717 Gene3D G3DSA:1.10.460.10 163 576 2.0E-123 T 23-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 TON_0315 7e70290494981634a36fff807bb263dd 717 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 635 673 1.8E-13 T 23-10-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 TON_0315 7e70290494981634a36fff807bb263dd 717 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 308 322 - T 23-10-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 TON_0315 7e70290494981634a36fff807bb263dd 717 SUPERFAMILY SSF56712 2 648 1.31E-164 T 23-10-2018 IPR023405 DNA topoisomerase, type IA, core domain TON_0315 7e70290494981634a36fff807bb263dd 717 Gene3D G3DSA:2.70.20.10 220 475 2.0E-123 T 23-10-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 TON_0315 7e70290494981634a36fff807bb263dd 717 SMART SM00493 2 129 1.1E-19 T 23-10-2018 IPR006171 TOPRIM domain TON_0315 7e70290494981634a36fff807bb263dd 717 Hamap MF_00952 DNA topoisomerase 1 [topA]. 2 705 51.356 T 23-10-2018 IPR028612 DNA topoisomerase I, type IA GO:0003677|GO:0003916|GO:0006265 TON_0202 9139c5a2047549caea9a47728a509c73 493 TIGRFAM TIGR01311 glycerol_kin: glycerol kinase 4 487 3.1E-216 T 23-10-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 TON_0202 9139c5a2047549caea9a47728a509c73 493 Hamap MF_00186 Glycerol kinase [glpK]. 2 488 57.306 T 23-10-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 TON_0202 9139c5a2047549caea9a47728a509c73 493 SUPERFAMILY SSF53067 249 487 1.51E-80 T 23-10-2018 TON_0202 9139c5a2047549caea9a47728a509c73 493 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 5 246 1.6E-88 T 23-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 TON_0202 9139c5a2047549caea9a47728a509c73 493 PIRSF PIRSF000538 2 492 6.6E-179 T 23-10-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 TON_0202 9139c5a2047549caea9a47728a509c73 493 Gene3D G3DSA:3.30.420.40 248 493 7.8E-91 T 23-10-2018 TON_0202 9139c5a2047549caea9a47728a509c73 493 Gene3D G3DSA:3.30.420.40 1 247 3.1E-115 T 23-10-2018 TON_0202 9139c5a2047549caea9a47728a509c73 493 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 132 144 - T 23-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 TON_0202 9139c5a2047549caea9a47728a509c73 493 SUPERFAMILY SSF53067 4 248 1.48E-95 T 23-10-2018 TON_0202 9139c5a2047549caea9a47728a509c73 493 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 355 375 - T 23-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 TON_0202 9139c5a2047549caea9a47728a509c73 493 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 256 441 2.8E-53 T 23-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 TON_1019 0b4b8bfd6ba192ad65b380b822a51eb6 269 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 4 237 3.1E-14 T 23-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain TON_1019 0b4b8bfd6ba192ad65b380b822a51eb6 269 Gene3D G3DSA:3.40.50.300 1 262 8.6E-54 T 23-10-2018 TON_1019 0b4b8bfd6ba192ad65b380b822a51eb6 269 PIRSF PIRSF005647 1 264 6.5E-62 T 23-10-2018 IPR014433 Nickel insertion ATPase/GTPase (CO dehydrogenase maturation factor), CooC type TON_1019 0b4b8bfd6ba192ad65b380b822a51eb6 269 SUPERFAMILY SSF52540 1 262 3.22E-34 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_0847 579c0c23cfa8e367f411cbe5d0008b44 189 Gene3D G3DSA:3.40.30.10 1 186 5.8E-67 T 23-10-2018 TON_0847 579c0c23cfa8e367f411cbe5d0008b44 189 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 158 182 7.2E-5 T 23-10-2018 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 TON_0847 579c0c23cfa8e367f411cbe5d0008b44 189 Pfam PF00578 AhpC/TSA family 4 135 2.4E-40 T 23-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 TON_0847 579c0c23cfa8e367f411cbe5d0008b44 189 SUPERFAMILY SSF52833 1 188 8.26E-63 T 23-10-2018 IPR036249 Thioredoxin-like superfamily TON_0847 579c0c23cfa8e367f411cbe5d0008b44 189 PIRSF PIRSF000239 1 189 2.3E-64 T 23-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 TON_1023 c2041a48a339c6a48253bbf2890078d8 540 Gene3D G3DSA:1.10.645.20 159 516 5.1E-132 T 23-10-2018 IPR038290 NADH-quinone oxidoreductase, subunit D superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_1023 c2041a48a339c6a48253bbf2890078d8 540 ProSitePatterns PS00535 Respiratory chain NADH dehydrogenase 49 Kd subunit signature. 195 206 - T 23-10-2018 IPR014029 NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_1023 c2041a48a339c6a48253bbf2890078d8 540 Pfam PF00374 Nickel-dependent hydrogenase 197 268 4.6E-16 T 23-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 TON_1023 c2041a48a339c6a48253bbf2890078d8 540 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 452 515 2.7E-12 T 23-10-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_1023 c2041a48a339c6a48253bbf2890078d8 540 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 274 443 7.2E-52 T 23-10-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_1023 c2041a48a339c6a48253bbf2890078d8 540 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 23 140 1.2E-27 T 23-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_1023 c2041a48a339c6a48253bbf2890078d8 540 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 82 140 2.0E-12 T 23-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_1023 c2041a48a339c6a48253bbf2890078d8 540 Gene3D G3DSA:3.30.460.80 5 118 7.8E-19 T 23-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_1023 c2041a48a339c6a48253bbf2890078d8 540 SUPERFAMILY SSF143243 15 173 1.02E-43 T 23-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_1023 c2041a48a339c6a48253bbf2890078d8 540 SUPERFAMILY SSF56762 168 516 1.7E-120 T 23-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_1331 dc0d7210cec2b3e823315e570e4bf9f0 104 Pfam PF03334 Na+/H+ antiporter subunit 6 86 1.8E-23 T 23-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 TON_1331 dc0d7210cec2b3e823315e570e4bf9f0 104 TIGRFAM TIGR01300 CPA3_mnhG_phaG: monovalent cation/proton antiporter, MnhG/PhaG subunit 5 99 4.1E-30 T 23-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 TON_1934 33c5be2bdc59be630769d80762d6bf7e 344 Gene3D G3DSA:3.40.50.11840 5 98 1.2E-30 T 23-10-2018 TON_1934 33c5be2bdc59be630769d80762d6bf7e 344 TIGRFAM TIGR03682 arCOG04112: diphthamide biosynthesis enzyme Dph2 17 324 3.6E-114 T 23-10-2018 IPR022428 Diphthamide synthesis Dph2, archaea GO:0017183 MetaCyc: PWY-6482|MetaCyc: PWY-7546 TON_1934 33c5be2bdc59be630769d80762d6bf7e 344 Gene3D G3DSA:3.40.50.11860 212 313 2.7E-34 T 23-10-2018 TON_1934 33c5be2bdc59be630769d80762d6bf7e 344 TIGRFAM TIGR00322 diphth2_R: diphthamide biosynthesis enzyme Dph1/Dph2 domain 4 313 2.6E-93 T 23-10-2018 IPR016435 Diphthamide synthesis DPH1/DPH2 MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 TON_1934 33c5be2bdc59be630769d80762d6bf7e 344 PIRSF PIRSF004967 1 335 2.8E-82 T 23-10-2018 IPR035435 Diphthamide synthesis DHP1/DPH2, eukaryotes and archaea GO:0017183 MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 TON_1934 33c5be2bdc59be630769d80762d6bf7e 344 Pfam PF01866 Putative diphthamide synthesis protein 26 319 4.0E-77 T 23-10-2018 IPR016435 Diphthamide synthesis DPH1/DPH2 MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 TON_1934 33c5be2bdc59be630769d80762d6bf7e 344 Gene3D G3DSA:3.40.50.11850 100 208 1.6E-39 T 23-10-2018 TON_0222 ff8860175b002ed9837965e28882f032 147 SUPERFAMILY SSF50249 23 147 1.8E-36 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold TON_0222 ff8860175b002ed9837965e28882f032 147 TIGRFAM TIGR00982 uS12_E_A: ribosomal protein uS12 9 147 2.7E-81 T 23-10-2018 IPR005680 Ribosomal protein S23, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0222 ff8860175b002ed9837965e28882f032 147 Hamap MF_00403_A 30S ribosomal protein S12 [rpsL]. 1 147 44.886 T 23-10-2018 IPR022863 Ribosomal protein S12, archaea TON_0222 ff8860175b002ed9837965e28882f032 147 PIRSF PIRSF002133 19 147 9.4E-37 T 23-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TON_0222 ff8860175b002ed9837965e28882f032 147 Pfam PF00164 Ribosomal protein S12/S23 32 146 8.1E-50 T 23-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TON_0222 ff8860175b002ed9837965e28882f032 147 Gene3D G3DSA:2.40.50.140 28 147 8.6E-51 T 23-10-2018 TON_1746 fe089657a90ed0c9ef942fd618819a11 103 Gene3D G3DSA:1.20.5.620 41 90 3.0E-6 T 23-10-2018 TON_1746 fe089657a90ed0c9ef942fd618819a11 103 SUPERFAMILY SSF81573 35 88 1.01E-6 T 23-10-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain superfamily TON_1746 fe089657a90ed0c9ef942fd618819a11 103 TIGRFAM TIGR02926 AhaH: ATP synthase archaeal, H subunit 5 89 8.2E-15 T 23-10-2018 IPR014275 ATPase, A1A0, subunit H TON_1474 9480011ed77811724676def3a82bc304 429 PIRSF PIRSF006809 1 422 9.9E-122 T 23-10-2018 IPR016496 GTPase HflX GO:0005525 TON_1474 9480011ed77811724676def3a82bc304 429 Gene3D G3DSA:3.40.50.11060 9 130 6.9E-34 T 23-10-2018 TON_1474 9480011ed77811724676def3a82bc304 429 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 189 326 5.2E-14 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 TON_1474 9480011ed77811724676def3a82bc304 429 Pfam PF16360 GTP-binding GTPase Middle Region 104 181 9.6E-19 T 23-10-2018 IPR032305 GTP-binding protein, middle domain TON_1474 9480011ed77811724676def3a82bc304 429 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 210 228 2.9E-6 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 TON_1474 9480011ed77811724676def3a82bc304 429 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 189 209 2.9E-6 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 TON_1474 9480011ed77811724676def3a82bc304 429 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 255 273 2.9E-6 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 TON_1474 9480011ed77811724676def3a82bc304 429 Gene3D G3DSA:3.40.50.300 189 362 2.2E-41 T 23-10-2018 TON_1474 9480011ed77811724676def3a82bc304 429 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 10 326 6.2E-94 T 23-10-2018 IPR016496 GTPase HflX GO:0005525 TON_1474 9480011ed77811724676def3a82bc304 429 Pfam PF13167 GTP-binding GTPase N-terminal 18 101 5.6E-24 T 23-10-2018 IPR025121 GTPase HflX, N-terminal TON_1474 9480011ed77811724676def3a82bc304 429 SUPERFAMILY SSF52540 189 402 8.42E-37 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_1474 9480011ed77811724676def3a82bc304 429 Hamap MF_00900 GTPase HflX [hflX]. 18 392 43.129 T 23-10-2018 IPR016496 GTPase HflX GO:0005525 TON_1474 9480011ed77811724676def3a82bc304 429 Pfam PF01926 50S ribosome-binding GTPase 190 308 3.0E-20 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 TON_0809 1f03bb6ac607aa8b3fa4d64d8f33ad3c 216 Pfam PF01569 PAP2 superfamily 84 189 1.6E-19 T 23-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase TON_0809 1f03bb6ac607aa8b3fa4d64d8f33ad3c 216 SUPERFAMILY SSF48317 11 203 1.7E-32 T 23-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily TON_0809 1f03bb6ac607aa8b3fa4d64d8f33ad3c 216 SMART SM00014 81 191 5.3E-11 T 23-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase TON_0809 1f03bb6ac607aa8b3fa4d64d8f33ad3c 216 Gene3D G3DSA:1.20.144.10 108 210 2.6E-17 T 23-10-2018 TON_1716 dca494fff305a0e85f79ba8fb0884256 652 Pfam PF03065 Glycosyl hydrolase family 57 5 288 1.1E-67 T 23-10-2018 IPR004300 Glycoside hydrolase family 57, N-terminal domain GO:0003824|GO:0005975 TON_1716 dca494fff305a0e85f79ba8fb0884256 652 Gene3D G3DSA:3.20.110.20 1 379 3.5E-177 T 23-10-2018 TON_1716 dca494fff305a0e85f79ba8fb0884256 652 Pfam PF09095 Domain of unknown function (DUF1926) 390 648 2.8E-78 T 23-10-2018 IPR015179 Alpha-amylase/4-alpha-glucanotransferase, C-terminal GO:0003824|GO:0005975|GO:0030246 TON_1716 dca494fff305a0e85f79ba8fb0884256 652 ProDom PD014405 HYDROLASE METABOLISM CARBOHYDRATE GLYCOSIDASE ALPHA-AMYLASE TRANSFERASE 4-ALPHA-GLUCANOTRANSFERASE GLYCOSYLTRANSFERASE FAMILY DIRECT 317 382 6.0E-30 T 23-10-2018 IPR015178 Alpha-amylase/4-alpha-glucanotransferase, central domain TON_1716 dca494fff305a0e85f79ba8fb0884256 652 SUPERFAMILY SSF88688 309 381 2.68E-36 T 23-10-2018 IPR028995 Glycoside hydrolase families 57/38, central domain superfamily TON_1716 dca494fff305a0e85f79ba8fb0884256 652 SUPERFAMILY SSF74650 387 651 4.08E-98 T 23-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 TON_1716 dca494fff305a0e85f79ba8fb0884256 652 Gene3D G3DSA:2.70.98.10 386 652 1.5E-86 T 23-10-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 TON_1716 dca494fff305a0e85f79ba8fb0884256 652 SUPERFAMILY SSF88713 3 307 1.62E-71 T 23-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 TON_1716 dca494fff305a0e85f79ba8fb0884256 652 Pfam PF09094 Domain of unknown function (DUF1925) 309 381 4.1E-36 T 23-10-2018 IPR015178 Alpha-amylase/4-alpha-glucanotransferase, central domain TON_1885 88a6758aaa8085ac0384b137f8a23789 466 SUPERFAMILY SSF51905 6 385 1.51E-46 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TON_1885 88a6758aaa8085ac0384b137f8a23789 466 Gene3D G3DSA:3.50.50.60 6 355 1.5E-111 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TON_1885 88a6758aaa8085ac0384b137f8a23789 466 Gene3D G3DSA:1.20.58.100 370 461 1.9E-17 T 23-10-2018 TON_1885 88a6758aaa8085ac0384b137f8a23789 466 Gene3D G3DSA:3.90.700.10 213 303 1.5E-111 T 23-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 TON_1885 88a6758aaa8085ac0384b137f8a23789 466 Pfam PF00890 FAD binding domain 6 348 1.3E-70 T 23-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 TON_1885 88a6758aaa8085ac0384b137f8a23789 466 SUPERFAMILY SSF46977 386 453 1.31E-19 T 23-10-2018 IPR037099 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 TON_1885 88a6758aaa8085ac0384b137f8a23789 466 Pfam PF02910 Fumarate reductase flavoprotein C-term 423 449 5.7E-6 T 23-10-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 TON_1885 88a6758aaa8085ac0384b137f8a23789 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 326 333 7.5E-5 T 23-10-2018 TON_1885 88a6758aaa8085ac0384b137f8a23789 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 3 25 7.5E-5 T 23-10-2018 TON_1885 88a6758aaa8085ac0384b137f8a23789 466 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 167 176 7.5E-5 T 23-10-2018 TON_1885 88a6758aaa8085ac0384b137f8a23789 466 SUPERFAMILY SSF56425 205 309 4.04E-33 T 23-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 TON_1885 88a6758aaa8085ac0384b137f8a23789 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 311 333 9.7E-9 T 23-10-2018 TON_1885 88a6758aaa8085ac0384b137f8a23789 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 9.7E-9 T 23-10-2018 TON_1885 88a6758aaa8085ac0384b137f8a23789 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 164 182 9.7E-9 T 23-10-2018 TON_1885 88a6758aaa8085ac0384b137f8a23789 466 TIGRFAM TIGR00551 nadB: L-aspartate oxidase 3 448 1.9E-146 T 23-10-2018 IPR005288 L-aspartate oxidase GO:0005737|GO:0008734|GO:0009435|GO:0055114 KEGG: 00250+1.4.3.16|KEGG: 00760+1.4.3.16|MetaCyc: PWY-5316|MetaCyc: PWY-7342 TON_0455 0cc37db19ad7947ba7beb1adc6dfaedd 86 Hamap MF_00327 50S ribosomal protein L37Ae [rpl37ae]. 3 71 25.106 T 23-10-2018 IPR002674 Ribosomal protein L37ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 TON_0455 0cc37db19ad7947ba7beb1adc6dfaedd 86 TIGRFAM TIGR00280 eL43_euk_arch: ribosomal protein eL43 1 80 5.3E-37 T 23-10-2018 IPR002674 Ribosomal protein L37ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 TON_0455 0cc37db19ad7947ba7beb1adc6dfaedd 86 Pfam PF01780 Ribosomal L37ae protein family 3 82 3.9E-33 T 23-10-2018 IPR002674 Ribosomal protein L37ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 TON_0455 0cc37db19ad7947ba7beb1adc6dfaedd 86 Gene3D G3DSA:2.20.25.30 9 86 3.4E-31 T 23-10-2018 IPR011331 Ribosomal protein L37ae/L37e GO:0003735|GO:0005622|GO:0005840|GO:0006412 TON_0455 0cc37db19ad7947ba7beb1adc6dfaedd 86 SUPERFAMILY SSF57829 10 80 1.53E-28 T 23-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 TON_1215 893dbc24ef42639d2aab3f6ae194c4c1 181 Pfam PF13023 HD domain 6 167 3.3E-32 T 23-10-2018 IPR006674 HD domain TON_1215 893dbc24ef42639d2aab3f6ae194c4c1 181 Gene3D G3DSA:1.10.3210.10 1 180 2.9E-62 T 23-10-2018 TON_1215 893dbc24ef42639d2aab3f6ae194c4c1 181 SUPERFAMILY SSF109604 2 172 3.14E-43 T 23-10-2018 TON_1215 893dbc24ef42639d2aab3f6ae194c4c1 181 SMART SM00471 23 142 4.9E-12 T 23-10-2018 IPR003607 HD/PDEase domain TON_1383 5a2607089d8f46c4cd12562a18250426 499 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 85 91 - T 23-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 TON_1383 5a2607089d8f46c4cd12562a18250426 499 Gene3D G3DSA:3.40.50.150 1 216 2.2E-35 T 23-10-2018 TON_1383 5a2607089d8f46c4cd12562a18250426 499 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 16 30 2.7E-14 T 23-10-2018 TON_1383 5a2607089d8f46c4cd12562a18250426 499 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 120 144 2.7E-14 T 23-10-2018 TON_1383 5a2607089d8f46c4cd12562a18250426 499 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 82 94 2.7E-14 T 23-10-2018 TON_1383 5a2607089d8f46c4cd12562a18250426 499 Pfam PF02384 N-6 DNA Methylase 10 217 1.6E-13 T 23-10-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 TON_1383 5a2607089d8f46c4cd12562a18250426 499 SUPERFAMILY SSF53335 11 244 5.84E-37 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TON_0389 cac63b1f7efb4e3056f0825cf092a157 263 SUPERFAMILY SSF48150 17 252 6.83E-79 T 23-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 TON_0389 cac63b1f7efb4e3056f0825cf092a157 263 Gene3D G3DSA:1.10.340.30 41 188 2.6E-84 T 23-10-2018 TON_0389 cac63b1f7efb4e3056f0825cf092a157 263 Hamap MF_01168 N-glycosylase/DNA lyase. 20 257 39.085 T 23-10-2018 IPR016544 N-glycosylase/DNA lyase GO:0000702|GO:0003906|GO:0006284 TON_0389 cac63b1f7efb4e3056f0825cf092a157 263 PIRSF PIRSF008955 12 263 1.6E-100 T 23-10-2018 IPR016544 N-glycosylase/DNA lyase GO:0000702|GO:0003906|GO:0006284 TON_0389 cac63b1f7efb4e3056f0825cf092a157 263 Pfam PF09171 N-glycosylase/DNA lyase 24 246 1.1E-83 T 23-10-2018 IPR015254 N-glycosylase/DNA lyase-like GO:0003906|GO:0016799 TON_0389 cac63b1f7efb4e3056f0825cf092a157 263 Gene3D G3DSA:1.10.1670.10 23 260 2.6E-84 T 23-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 TON_0480 ffb58259bbfee29ba1947c5b161d8c14 103 SUPERFAMILY SSF51182 1 100 7.29E-23 T 23-10-2018 IPR011051 RmlC-like cupin domain superfamily TON_0480 ffb58259bbfee29ba1947c5b161d8c14 103 Pfam PF07883 Cupin domain 33 100 7.4E-17 T 23-10-2018 IPR013096 Cupin 2, conserved barrel TON_0480 ffb58259bbfee29ba1947c5b161d8c14 103 Gene3D G3DSA:2.60.120.10 4 103 9.5E-25 T 23-10-2018 IPR014710 RmlC-like jelly roll fold TON_0280 adb7945a2f22853b694dfd1db52118ea 165 Gene3D G3DSA:3.30.70.20 35 159 1.2E-39 T 23-10-2018 TON_0280 adb7945a2f22853b694dfd1db52118ea 165 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 78 89 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TON_0280 adb7945a2f22853b694dfd1db52118ea 165 Gene3D G3DSA:3.30.70.20 2 34 2.3E-5 T 23-10-2018 TON_0280 adb7945a2f22853b694dfd1db52118ea 165 Pfam PF13247 4Fe-4S dicluster domain 44 133 2.6E-26 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TON_0280 adb7945a2f22853b694dfd1db52118ea 165 SUPERFAMILY SSF54862 3 148 5.96E-49 T 23-10-2018 TON_1642 ad458c598142e43051530fbcd12ab781 1771 SUPERFAMILY SSF55608 1260 1379 1.87E-9 T 23-10-2018 IPR027434 Homing endonuclease TON_1642 ad458c598142e43051530fbcd12ab781 1771 Pfam PF03833 DNA polymerase II large subunit DP2 12 960 0.0 T 23-10-2018 IPR016033 DNA polymerase II large subunit DP2, N-terminal KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TON_1642 ad458c598142e43051530fbcd12ab781 1771 Gene3D G3DSA:3.10.28.10 1177 1334 2.5E-29 T 23-10-2018 IPR027434 Homing endonuclease TON_1642 ad458c598142e43051530fbcd12ab781 1771 Gene3D G3DSA:2.170.16.10 1364 1434 4.6E-14 T 23-10-2018 TON_1642 ad458c598142e43051530fbcd12ab781 1771 Gene3D G3DSA:2.170.16.10 961 1112 1.8E-44 T 23-10-2018 TON_1642 ad458c598142e43051530fbcd12ab781 1771 Pfam PF14890 Intein splicing domain 1006 1433 2.7E-25 T 23-10-2018 TON_1642 ad458c598142e43051530fbcd12ab781 1771 TIGRFAM TIGR01445 intein_Nterm: intein N-terminal splicing region 961 1057 2.8E-14 T 23-10-2018 IPR006141 Intein N-terminal splicing region GO:0016539 Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TON_1642 ad458c598142e43051530fbcd12ab781 1771 PRINTS PR00379 Intein signature 1274 1286 4.3E-8 T 23-10-2018 IPR006142 Intein GO:0016539 TON_1642 ad458c598142e43051530fbcd12ab781 1771 PRINTS PR00379 Intein signature 1044 1057 4.3E-8 T 23-10-2018 IPR006142 Intein GO:0016539 TON_1642 ad458c598142e43051530fbcd12ab781 1771 PRINTS PR00379 Intein signature 1410 1427 4.3E-8 T 23-10-2018 IPR006142 Intein GO:0016539 TON_1642 ad458c598142e43051530fbcd12ab781 1771 PRINTS PR00379 Intein signature 1178 1190 4.3E-8 T 23-10-2018 IPR006142 Intein GO:0016539 TON_1642 ad458c598142e43051530fbcd12ab781 1771 Pfam PF14528 LAGLIDADG-like domain 1273 1367 5.7E-13 T 23-10-2018 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 TON_1642 ad458c598142e43051530fbcd12ab781 1771 SMART SM00306 959 1081 1.7E-25 T 23-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TON_1642 ad458c598142e43051530fbcd12ab781 1771 Hamap MF_00324 DNA polymerase II large subunit [polC]. 1 1698 401.704 T 23-10-2018 IPR004475 DNA polymerase II large subunit DP2 GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TON_1642 ad458c598142e43051530fbcd12ab781 1771 TIGRFAM TIGR00354 polC: DNA polymerase II, large subunit DP2 7 974 0.0 T 23-10-2018 IPR004475 DNA polymerase II large subunit DP2 GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TON_1642 ad458c598142e43051530fbcd12ab781 1771 SUPERFAMILY SSF51294 961 1435 2.75E-33 T 23-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TON_1283 034c8665d20fffad606cc30334afebca 388 Gene3D G3DSA:3.40.50.300 219 311 1.6E-5 T 23-10-2018 TON_1283 034c8665d20fffad606cc30334afebca 388 SUPERFAMILY SSF81271 309 386 9.94E-19 T 23-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 TON_1283 034c8665d20fffad606cc30334afebca 388 SUPERFAMILY SSF52540 84 323 7.24E-51 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_1283 034c8665d20fffad606cc30334afebca 388 Pfam PF16897 C-terminal region of MMR_HSR1 domain 206 310 5.8E-19 T 23-10-2018 IPR031662 GTP binding protein, second domain TON_1283 034c8665d20fffad606cc30334afebca 388 Gene3D G3DSA:3.10.20.30 312 388 8.2E-29 T 23-10-2018 IPR012675 Beta-grasp domain superfamily TON_1283 034c8665d20fffad606cc30334afebca 388 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 83 190 1.7E-13 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 TON_1283 034c8665d20fffad606cc30334afebca 388 Pfam PF02824 TGS domain 315 386 4.5E-24 T 23-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 TON_1283 034c8665d20fffad606cc30334afebca 388 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 85 105 8.2E-28 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 TON_1283 034c8665d20fffad606cc30334afebca 388 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 106 124 8.2E-28 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 TON_1283 034c8665d20fffad606cc30334afebca 388 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 150 168 8.2E-28 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 TON_1283 034c8665d20fffad606cc30334afebca 388 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 133 148 8.2E-28 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 TON_1283 034c8665d20fffad606cc30334afebca 388 Gene3D G3DSA:3.40.50.300 71 203 4.1E-34 T 23-10-2018 TON_1283 034c8665d20fffad606cc30334afebca 388 Pfam PF01926 50S ribosome-binding GTPase 84 184 8.1E-21 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 TON_0333 2c30669056669bf67e38ec8829236ae2 70 SUPERFAMILY SSF46785 4 52 4.34E-8 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TON_0333 2c30669056669bf67e38ec8829236ae2 70 Pfam PF01022 Bacterial regulatory protein, arsR family 4 44 1.0E-5 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TON_0333 2c30669056669bf67e38ec8829236ae2 70 Gene3D G3DSA:1.10.10.10 2 70 9.6E-8 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TON_1614 86690c1883fb4d798359636b561a6a83 276 Pfam PF04055 Radical SAM superfamily 21 160 6.3E-11 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TON_1614 86690c1883fb4d798359636b561a6a83 276 SUPERFAMILY SSF102114 13 225 2.62E-26 T 23-10-2018 TON_1614 86690c1883fb4d798359636b561a6a83 276 Gene3D G3DSA:3.20.20.70 6 220 8.7E-18 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TON_1614 86690c1883fb4d798359636b561a6a83 276 SMART SM00729 14 217 4.0E-4 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TON_0835 24324c950e80b197665f85b49bba2a98 800 Pfam PF00403 Heavy-metal-associated domain 75 135 3.6E-16 T 23-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 TON_0835 24324c950e80b197665f85b49bba2a98 800 Pfam PF00403 Heavy-metal-associated domain 4 65 1.7E-15 T 23-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 TON_0835 24324c950e80b197665f85b49bba2a98 800 Gene3D G3DSA:3.40.1110.10 498 618 1.1E-101 T 23-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 TON_0835 24324c950e80b197665f85b49bba2a98 800 TIGRFAM TIGR00003 TIGR00003: copper ion binding protein 2 67 1.1E-18 T 23-10-2018 IPR006122 Heavy metal-associated domain, copper ion-binding GO:0005507 Reactome: R-HSA-936837 TON_0835 24324c950e80b197665f85b49bba2a98 800 TIGRFAM TIGR00003 TIGR00003: copper ion binding protein 75 135 3.4E-14 T 23-10-2018 IPR006122 Heavy metal-associated domain, copper ion-binding GO:0005507 Reactome: R-HSA-936837 TON_0835 24324c950e80b197665f85b49bba2a98 800 SUPERFAMILY SSF81653 290 386 3.53E-31 T 23-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 TON_0835 24324c950e80b197665f85b49bba2a98 800 Gene3D G3DSA:3.30.70.100 71 134 1.1E-23 T 23-10-2018 TON_0835 24324c950e80b197665f85b49bba2a98 800 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 489 495 - T 23-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 TON_0835 24324c950e80b197665f85b49bba2a98 800 SUPERFAMILY SSF56784 485 793 1.08E-63 T 23-10-2018 IPR036412 HAD-like superfamily TON_0835 24324c950e80b197665f85b49bba2a98 800 Gene3D G3DSA:3.40.50.1000 468 738 1.1E-101 T 23-10-2018 IPR023214 HAD superfamily TON_0835 24324c950e80b197665f85b49bba2a98 800 SUPERFAMILY SSF81665 251 479 9.94E-14 T 23-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 TON_0835 24324c950e80b197665f85b49bba2a98 800 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 259 767 2.4E-106 T 23-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 TON_0835 24324c950e80b197665f85b49bba2a98 800 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 204 796 1.1E-185 T 23-10-2018 TON_0835 24324c950e80b197665f85b49bba2a98 800 Pfam PF00702 haloacid dehalogenase-like hydrolase 485 700 4.0E-47 T 23-10-2018 TON_0835 24324c950e80b197665f85b49bba2a98 800 PRINTS PR00943 Copper-transporting ATPase signature 720 734 2.9E-13 T 23-10-2018 TON_0835 24324c950e80b197665f85b49bba2a98 800 PRINTS PR00943 Copper-transporting ATPase signature 116 136 2.9E-13 T 23-10-2018 TON_0835 24324c950e80b197665f85b49bba2a98 800 PRINTS PR00943 Copper-transporting ATPase signature 409 423 2.9E-13 T 23-10-2018 TON_0835 24324c950e80b197665f85b49bba2a98 800 PRINTS PR00943 Copper-transporting ATPase signature 663 680 2.9E-13 T 23-10-2018 TON_0835 24324c950e80b197665f85b49bba2a98 800 PRINTS PR00943 Copper-transporting ATPase signature 256 275 2.9E-13 T 23-10-2018 TON_0835 24324c950e80b197665f85b49bba2a98 800 SUPERFAMILY SSF55008 1 68 7.59E-21 T 23-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 TON_0835 24324c950e80b197665f85b49bba2a98 800 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 223 795 7.0E-201 T 23-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 TON_0835 24324c950e80b197665f85b49bba2a98 800 Gene3D G3DSA:2.70.150.20 279 391 5.2E-46 T 23-10-2018 TON_0835 24324c950e80b197665f85b49bba2a98 800 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 686 705 2.5E-26 T 23-10-2018 TON_0835 24324c950e80b197665f85b49bba2a98 800 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 709 721 2.5E-26 T 23-10-2018 TON_0835 24324c950e80b197665f85b49bba2a98 800 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 487 501 2.5E-26 T 23-10-2018 TON_0835 24324c950e80b197665f85b49bba2a98 800 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 611 622 2.5E-26 T 23-10-2018 TON_0835 24324c950e80b197665f85b49bba2a98 800 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 336 350 2.5E-26 T 23-10-2018 TON_0835 24324c950e80b197665f85b49bba2a98 800 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 633 643 2.5E-26 T 23-10-2018 TON_0835 24324c950e80b197665f85b49bba2a98 800 Pfam PF00122 E1-E2 ATPase 287 466 6.6E-61 T 23-10-2018 TON_0835 24324c950e80b197665f85b49bba2a98 800 Gene3D G3DSA:3.30.70.100 1 66 2.1E-22 T 23-10-2018 TON_0835 24324c950e80b197665f85b49bba2a98 800 SUPERFAMILY SSF55008 73 138 3.93E-21 T 23-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 TON_1958 dbd6d7d7b25b0ec2e5c9ace7ffb79a9c 334 SUPERFAMILY SSF50331 237 313 6.8E-6 T 23-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal TON_1958 dbd6d7d7b25b0ec2e5c9ace7ffb79a9c 334 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TON_1958 dbd6d7d7b25b0ec2e5c9ace7ffb79a9c 334 Gene3D G3DSA:3.40.50.300 3 236 1.3E-74 T 23-10-2018 TON_1958 dbd6d7d7b25b0ec2e5c9ace7ffb79a9c 334 SMART SM00382 27 218 4.7E-17 T 23-10-2018 IPR003593 AAA+ ATPase domain TON_1958 dbd6d7d7b25b0ec2e5c9ace7ffb79a9c 334 Pfam PF00005 ABC transporter 25 160 5.6E-34 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TON_1958 dbd6d7d7b25b0ec2e5c9ace7ffb79a9c 334 SUPERFAMILY SSF52540 4 241 1.64E-87 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_0934 cd8411369175a698b6860d1232bf41ae 356 Gene3D G3DSA:3.40.50.10470 159 356 1.8E-60 T 23-10-2018 TON_0934 cd8411369175a698b6860d1232bf41ae 356 Pfam PF01008 Initiation factor 2 subunit family 55 343 6.8E-83 T 23-10-2018 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 TON_0934 cd8411369175a698b6860d1232bf41ae 356 TIGRFAM TIGR00524 eIF-2B_rel: eIF-2B alpha/beta/delta-related uncharacterized proteins 42 343 8.5E-116 T 23-10-2018 IPR011559 Initiation factor 2B alpha/beta/delta GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 TON_0934 cd8411369175a698b6860d1232bf41ae 356 SUPERFAMILY SSF100950 12 350 1.67E-115 T 23-10-2018 IPR037171 NagB/RpiA transferase-like TON_0934 cd8411369175a698b6860d1232bf41ae 356 Gene3D G3DSA:1.20.120.420 11 156 9.2E-47 T 23-10-2018 IPR027363 Methylthioribose-1-phosphate isomerase, N-terminal KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 TON_0934 cd8411369175a698b6860d1232bf41ae 356 TIGRFAM TIGR00512 salvage_mtnA: S-methyl-5-thioribose-1-phosphate isomerase 15 342 1.1E-129 T 23-10-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 TON_0934 cd8411369175a698b6860d1232bf41ae 356 Hamap MF_01678 Putative methylthioribose-1-phosphate isomerase [mtnA]. 13 353 40.084 T 23-10-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 TON_0209 437b3071ce328c9362b88c1c9db389c7 226 PIRSF PIRSF000887 3 224 5.3E-57 T 23-10-2018 IPR024173 Phosphoesterase, MJ0037 TON_0209 437b3071ce328c9362b88c1c9db389c7 226 SUPERFAMILY SSF56300 17 127 1.39E-15 T 23-10-2018 TON_0209 437b3071ce328c9362b88c1c9db389c7 226 TIGRFAM TIGR00024 SbcD_rel_arch: putative phosphoesterase 7 221 7.7E-43 T 23-10-2018 IPR004376 Conserved hypothetical protein CHP00024, phosphoesterase-like TON_0209 437b3071ce328c9362b88c1c9db389c7 226 Gene3D G3DSA:3.60.21.10 16 160 1.0E-10 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like TON_0209 437b3071ce328c9362b88c1c9db389c7 226 Pfam PF00149 Calcineurin-like phosphoesterase 17 112 3.7E-7 T 23-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 TON_1884 38855944e9e376fc133594760af0d245 486 SMART SM00116 102 150 3.7E-11 T 23-10-2018 IPR000644 CBS domain TON_1884 38855944e9e376fc133594760af0d245 486 SMART SM00116 160 208 1.3E-12 T 23-10-2018 IPR000644 CBS domain TON_1884 38855944e9e376fc133594760af0d245 486 Pfam PF00571 CBS domain 100 146 8.8E-13 T 23-10-2018 IPR000644 CBS domain TON_1884 38855944e9e376fc133594760af0d245 486 Pfam PF00571 CBS domain 153 205 5.9E-17 T 23-10-2018 IPR000644 CBS domain TON_1884 38855944e9e376fc133594760af0d245 486 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 14 484 80.545 T 23-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 TON_1884 38855944e9e376fc133594760af0d245 486 PIRSF PIRSF000130 3 486 2.2E-195 T 23-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 TON_1884 38855944e9e376fc133594760af0d245 486 SUPERFAMILY SSF51412 10 475 5.49E-113 T 23-10-2018 TON_1884 38855944e9e376fc133594760af0d245 486 Gene3D G3DSA:3.20.20.70 3 484 1.3E-198 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TON_1884 38855944e9e376fc133594760af0d245 486 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 14 471 5.8E-149 T 23-10-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 TON_1884 38855944e9e376fc133594760af0d245 486 SMART SM01240 13 471 4.5E-262 T 23-10-2018 TON_1884 38855944e9e376fc133594760af0d245 486 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 14 453 9.4E-191 T 23-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 TON_1884 38855944e9e376fc133594760af0d245 486 SUPERFAMILY SSF54631 72 204 1.16E-33 T 23-10-2018 TON_1884 38855944e9e376fc133594760af0d245 486 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 292 304 - T 23-10-2018 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 TON_1626 19bb11764cf14ff5f34093878989aef6 752 Pfam PF03176 MMPL family 525 741 2.8E-23 T 23-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 TON_1626 19bb11764cf14ff5f34093878989aef6 752 Pfam PF03176 MMPL family 45 403 4.3E-37 T 23-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 TON_1626 19bb11764cf14ff5f34093878989aef6 752 SUPERFAMILY SSF82866 146 364 1.57E-43 T 23-10-2018 TON_1626 19bb11764cf14ff5f34093878989aef6 752 Gene3D G3DSA:1.20.1640.10 580 750 1.2E-13 T 23-10-2018 TON_1626 19bb11764cf14ff5f34093878989aef6 752 Gene3D G3DSA:1.20.1640.10 193 374 1.9E-25 T 23-10-2018 TON_1626 19bb11764cf14ff5f34093878989aef6 752 SUPERFAMILY SSF82866 529 746 1.96E-37 T 23-10-2018 TON_1626 19bb11764cf14ff5f34093878989aef6 752 TIGRFAM TIGR00921 2A067: efflux transporter, putative, hydrophobe/amphiphile efflux-3 (HAE3) family 12 741 9.2E-236 T 23-10-2018 IPR004767 Hydrophobe/amphiphile efflux-3 HAE3 TON_1855 16be8746e710de3f4ea03dce9354a790 391 Pfam PF00534 Glycosyl transferases group 1 194 355 6.3E-37 T 23-10-2018 IPR001296 Glycosyl transferase, family 1 TON_1855 16be8746e710de3f4ea03dce9354a790 391 SUPERFAMILY SSF53756 13 386 1.49E-79 T 23-10-2018 TON_1855 16be8746e710de3f4ea03dce9354a790 391 Pfam PF13439 Glycosyltransferase Family 4 20 187 3.6E-17 T 23-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 TON_1855 16be8746e710de3f4ea03dce9354a790 391 Gene3D G3DSA:3.40.50.2000 184 369 3.7E-70 T 23-10-2018 TON_1855 16be8746e710de3f4ea03dce9354a790 391 Gene3D G3DSA:3.40.50.2000 20 379 3.7E-70 T 23-10-2018 TON_0283 5feb13ddb5059ebe412da13aece94704 81 Gene3D G3DSA:2.40.50.970 1 74 5.2E-33 T 23-10-2018 IPR037254 HupF/HypC superfamily TON_0283 5feb13ddb5059ebe412da13aece94704 81 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 2 9 7.8E-14 T 23-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC TON_0283 5feb13ddb5059ebe412da13aece94704 81 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 17 33 7.8E-14 T 23-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC TON_0283 5feb13ddb5059ebe412da13aece94704 81 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 38 54 7.8E-14 T 23-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC TON_0283 5feb13ddb5059ebe412da13aece94704 81 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 56 68 7.8E-14 T 23-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC TON_0283 5feb13ddb5059ebe412da13aece94704 81 SUPERFAMILY SSF159127 1 76 1.83E-28 T 23-10-2018 IPR037254 HupF/HypC superfamily TON_0283 5feb13ddb5059ebe412da13aece94704 81 Pfam PF01455 HupF/HypC family 1 65 1.0E-29 T 23-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC TON_0283 5feb13ddb5059ebe412da13aece94704 81 TIGRFAM TIGR00074 hypC_hupF: hydrogenase assembly chaperone HypC/HupF 1 74 6.2E-30 T 23-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC TON_0283 5feb13ddb5059ebe412da13aece94704 81 ProSitePatterns PS01097 Hydrogenases expression/synthesis hupF/hypC family signature. 1 9 - T 23-10-2018 IPR019812 Hydrogenase assembly chaperone, conserved site TON_1762 66cc0c709396d119c02470043db9a16d 233 Gene3D G3DSA:2.40.30.10 3 84 3.0E-12 T 23-10-2018 TON_1762 66cc0c709396d119c02470043db9a16d 233 SUPERFAMILY SSF63380 4 85 8.24E-19 T 23-10-2018 IPR017938 Riboflavin synthase-like beta-barrel TON_1762 66cc0c709396d119c02470043db9a16d 233 Gene3D G3DSA:3.40.50.80 86 196 1.7E-27 T 23-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain TON_1762 66cc0c709396d119c02470043db9a16d 233 SUPERFAMILY SSF52343 80 229 1.28E-32 T 23-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain TON_1762 66cc0c709396d119c02470043db9a16d 233 Pfam PF00175 Oxidoreductase NAD-binding domain 94 183 3.5E-8 T 23-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 TON_1762 66cc0c709396d119c02470043db9a16d 233 PIRSF PIRSF006816 1 232 4.5E-76 T 23-10-2018 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 TON_1762 66cc0c709396d119c02470043db9a16d 233 Hamap MF_01211 Dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit [pyrK]. 2 231 34.385 T 23-10-2018 IPR023455 Dihydroorotate dehydrogenase electron transfer subunit TON_1762 66cc0c709396d119c02470043db9a16d 233 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 197 229 1.5E-10 T 23-10-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain TON_1368 958ecf89cf3d8bd932ae995f75691775 181 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 88 123 - T 23-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 TON_1368 958ecf89cf3d8bd932ae995f75691775 181 SUPERFAMILY SSF53927 24 153 3.58E-40 T 23-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 TON_1368 958ecf89cf3d8bd932ae995f75691775 181 Gene3D G3DSA:3.40.140.10 20 168 3.8E-48 T 23-10-2018 TON_1368 958ecf89cf3d8bd932ae995f75691775 181 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 23 134 4.6E-29 T 23-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain TON_1368 958ecf89cf3d8bd932ae995f75691775 181 PIRSF PIRSF006019 15 171 7.8E-57 T 23-10-2018 IPR016473 Deoxycytidylate deaminase GO:0004132|GO:0006220|GO:0008270 KEGG: 00240+3.5.4.12|MetaCyc: PWY-7210|Reactome: R-HSA-499943 TON_1866 395336678b40562b7f7ab3c40700b30a 91 Pfam PF00736 EF-1 guanine nucleotide exchange domain 9 91 5.3E-20 T 23-10-2018 IPR014038 Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain GO:0003746|GO:0006414 Reactome: R-HSA-156842 TON_1866 395336678b40562b7f7ab3c40700b30a 91 TIGRFAM TIGR00489 aEF-1_beta: translation elongation factor aEF-1 beta 7 90 1.6E-21 T 23-10-2018 IPR004542 Translation elongation factor EF1B, beta chain, archaeal GO:0003746|GO:0006414 TON_1866 395336678b40562b7f7ab3c40700b30a 91 PIRSF PIRSF006521 3 91 6.8E-32 T 23-10-2018 IPR004542 Translation elongation factor EF1B, beta chain, archaeal GO:0003746|GO:0006414 TON_1866 395336678b40562b7f7ab3c40700b30a 91 SUPERFAMILY SSF54984 9 91 7.19E-21 T 23-10-2018 IPR036219 Translation elongation factor eEF-1beta-like superfamily Reactome: R-HSA-156842 TON_1866 395336678b40562b7f7ab3c40700b30a 91 Hamap MF_00043 Elongation factor 1-beta [ef1b]. 1 91 40.544 T 23-10-2018 IPR004542 Translation elongation factor EF1B, beta chain, archaeal GO:0003746|GO:0006414 TON_1866 395336678b40562b7f7ab3c40700b30a 91 Gene3D G3DSA:3.30.70.60 1 91 8.1E-35 T 23-10-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 TON_1866 395336678b40562b7f7ab3c40700b30a 91 SMART SM00888 5 91 3.2E-31 T 23-10-2018 IPR014038 Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain GO:0003746|GO:0006414 Reactome: R-HSA-156842 TON_0281 1991ee60d2f208c4e563e2a6b92b4deb 689 SUPERFAMILY SSF50692 550 687 2.49E-46 T 23-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily TON_0281 1991ee60d2f208c4e563e2a6b92b4deb 689 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 9 58 4.3E-9 T 23-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_0281 1991ee60d2f208c4e563e2a6b92b4deb 689 SMART SM00926 5 60 2.0E-9 T 23-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_0281 1991ee60d2f208c4e563e2a6b92b4deb 689 Gene3D G3DSA:3.40.228.10 144 344 6.5E-170 T 23-10-2018 TON_0281 1991ee60d2f208c4e563e2a6b92b4deb 689 Gene3D G3DSA:2.40.40.20 566 689 1.4E-41 T 23-10-2018 TON_0281 1991ee60d2f208c4e563e2a6b92b4deb 689 ProSitePatterns PS00490 Prokaryotic molybdopterin oxidoreductases signature 2. 436 453 - T 23-10-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 TON_0281 1991ee60d2f208c4e563e2a6b92b4deb 689 Gene3D G3DSA:3.40.50.740 74 536 6.5E-170 T 23-10-2018 TON_0281 1991ee60d2f208c4e563e2a6b92b4deb 689 TIGRFAM TIGR01591 Fdh-alpha: formate dehydrogenase, alpha subunit 10 684 7.8E-215 T 23-10-2018 IPR006478 Formate dehydrogenase, alpha subunit GO:0008863|GO:0015942|GO:0055114 KEGG: 00630+1.17.1.9|KEGG: 00680+1.17.1.9|MetaCyc: PWY-1881|MetaCyc: PWY-5497|MetaCyc: PWY-6696|MetaCyc: PWY-7985 TON_0281 1991ee60d2f208c4e563e2a6b92b4deb 689 Pfam PF01568 Molydopterin dinucleotide binding domain 578 680 9.4E-30 T 23-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 TON_0281 1991ee60d2f208c4e563e2a6b92b4deb 689 Pfam PF00384 Molybdopterin oxidoreductase 63 490 4.5E-96 T 23-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_0281 1991ee60d2f208c4e563e2a6b92b4deb 689 SUPERFAMILY SSF53706 6 580 1.44E-198 T 23-10-2018 TON_0281 1991ee60d2f208c4e563e2a6b92b4deb 689 Gene3D G3DSA:2.20.25.90 2 65 6.1E-12 T 23-10-2018 TON_1477 8ce4ae6f8a8ec345a1c998d08b32b274 102 TIGRFAM TIGR02179 PorD_KorD: 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate family 30 101 5.2E-34 T 23-10-2018 IPR011898 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate GO:0016625|GO:0051539 TON_1477 8ce4ae6f8a8ec345a1c998d08b32b274 102 Gene3D G3DSA:3.30.70.20 66 102 6.5E-10 T 23-10-2018 TON_1477 8ce4ae6f8a8ec345a1c998d08b32b274 102 Gene3D G3DSA:3.30.70.20 27 65 8.6E-6 T 23-10-2018 TON_1477 8ce4ae6f8a8ec345a1c998d08b32b274 102 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 80 91 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TON_1477 8ce4ae6f8a8ec345a1c998d08b32b274 102 Pfam PF14697 4Fe-4S dicluster domain 44 97 3.3E-10 T 23-10-2018 TON_1477 8ce4ae6f8a8ec345a1c998d08b32b274 102 SUPERFAMILY SSF54862 30 101 1.31E-24 T 23-10-2018 TON_1758 ff614a63519c4cf61085f995eace9b1a 276 PIRSF PIRSF036668 1 275 1.1E-129 T 23-10-2018 IPR012121 ATPase, PP-loop, MJ1599-related TON_1758 ff614a63519c4cf61085f995eace9b1a 276 Pfam PF06508 Queuosine biosynthesis protein QueC 54 134 2.9E-9 T 23-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 TON_1758 ff614a63519c4cf61085f995eace9b1a 276 Gene3D G3DSA:3.40.50.620 2 192 4.3E-31 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TON_1758 ff614a63519c4cf61085f995eace9b1a 276 SUPERFAMILY SSF52402 26 200 7.94E-31 T 23-10-2018 TON_1847 61f36e3fb7f8abe7724e9b2d6c96dff3 132 SUPERFAMILY SSF88723 1 129 7.57E-23 T 23-10-2018 IPR029060 PIN-like domain superfamily TON_1847 61f36e3fb7f8abe7724e9b2d6c96dff3 132 Pfam PF01850 PIN domain 2 121 9.6E-18 T 23-10-2018 IPR002716 PIN domain TON_1847 61f36e3fb7f8abe7724e9b2d6c96dff3 132 Gene3D G3DSA:3.40.50.1010 1 127 1.9E-15 T 23-10-2018 TON_1847 61f36e3fb7f8abe7724e9b2d6c96dff3 132 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 2 127 9.589 T 23-10-2018 IPR022907 VapC family GO:0004540 TON_1491 fda65aabc9c0b9a7df3233c1e2644470 104 Gene3D G3DSA:3.30.70.120 1 104 5.8E-37 T 23-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal TON_1491 fda65aabc9c0b9a7df3233c1e2644470 104 SUPERFAMILY SSF54913 2 101 9.64E-34 T 23-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta TON_1491 fda65aabc9c0b9a7df3233c1e2644470 104 Pfam PF03091 CutA1 divalent ion tolerance protein 4 100 1.2E-31 T 23-10-2018 IPR004323 Divalent ion tolerance protein, CutA GO:0010038 TON_0131 e50e3ff96c01c708c225f0adcce1504c 277 Pfam PF01048 Phosphorylase superfamily 30 252 1.7E-44 T 23-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 TON_0131 e50e3ff96c01c708c225f0adcce1504c 277 SUPERFAMILY SSF53167 17 246 4.45E-74 T 23-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 TON_0131 e50e3ff96c01c708c225f0adcce1504c 277 Gene3D G3DSA:3.40.50.1580 6 259 1.6E-85 T 23-10-2018 TON_0131 e50e3ff96c01c708c225f0adcce1504c 277 ProSitePatterns PS01232 Purine and other phosphorylases family 1 signature. 75 90 - T 23-10-2018 IPR018016 Nucleoside phosphorylase, conserved site GO:0016763 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-73614|Reactome: R-HSA-73621 TON_0131 e50e3ff96c01c708c225f0adcce1504c 277 TIGRFAM TIGR01718 Uridine-psphlse: uridine phosphorylase 17 256 4.2E-96 T 23-10-2018 IPR010058 Uridine phosphorylase GO:0004850|GO:0005737|GO:0009166 KEGG: 00240+2.4.2.3|KEGG: 00983+2.4.2.3|MetaCyc: PWY-5532 TON_1557 fb48f2114dcfa7e3f7c61c7de3bd0f75 425 Pfam PF01938 TRAM domain 367 424 4.5E-8 T 23-10-2018 IPR002792 TRAM domain TON_1557 fb48f2114dcfa7e3f7c61c7de3bd0f75 425 Gene3D G3DSA:3.40.50.12160 2 123 9.0E-26 T 23-10-2018 IPR038135 Methylthiotransferase, N-terminal domain superfamily TON_1557 fb48f2114dcfa7e3f7c61c7de3bd0f75 425 Gene3D G3DSA:3.80.30.20 138 369 5.9E-77 T 23-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe TON_1557 fb48f2114dcfa7e3f7c61c7de3bd0f75 425 Pfam PF04055 Radical SAM superfamily 142 314 2.1E-24 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TON_1557 fb48f2114dcfa7e3f7c61c7de3bd0f75 425 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 3 421 2.2E-130 T 23-10-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 TON_1557 fb48f2114dcfa7e3f7c61c7de3bd0f75 425 SUPERFAMILY SSF102114 127 363 2.49E-54 T 23-10-2018 TON_1557 fb48f2114dcfa7e3f7c61c7de3bd0f75 425 SMART SM00729 138 355 4.9E-63 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TON_1557 fb48f2114dcfa7e3f7c61c7de3bd0f75 425 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 142 162 - T 23-10-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 TON_1557 fb48f2114dcfa7e3f7c61c7de3bd0f75 425 TIGRFAM TIGR01578 MiaB-like-B: MiaB-like tRNA modifying enzyme, archaeal-type 3 423 2.5E-142 T 23-10-2018 IPR006466 MiaB-like tRNA modifying enzyme, archaeal-type Reactome: R-HSA-6782315 TON_1557 fb48f2114dcfa7e3f7c61c7de3bd0f75 425 Pfam PF00919 Uncharacterized protein family UPF0004 3 83 2.4E-22 T 23-10-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 TON_1772 199fd7288e00bef3172c41f0bb091467 443 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 137 441 9.9E-139 T 23-10-2018 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 TON_1772 199fd7288e00bef3172c41f0bb091467 443 Gene3D G3DSA:3.30.590.10 103 443 4.7E-126 T 23-10-2018 TON_1772 199fd7288e00bef3172c41f0bb091467 443 SUPERFAMILY SSF54368 19 93 1.7E-19 T 23-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 TON_1772 199fd7288e00bef3172c41f0bb091467 443 Gene3D G3DSA:3.10.20.70 6 102 3.8E-23 T 23-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 TON_1772 199fd7288e00bef3172c41f0bb091467 443 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 226 241 - T 23-10-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 TON_1772 199fd7288e00bef3172c41f0bb091467 443 SUPERFAMILY SSF55931 101 442 2.84E-120 T 23-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 TON_1772 199fd7288e00bef3172c41f0bb091467 443 ProSitePatterns PS00180 Glutamine synthetase signature 1. 52 70 - T 23-10-2018 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 TON_1772 199fd7288e00bef3172c41f0bb091467 443 SMART SM01230 100 343 1.7E-131 T 23-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 TON_1772 199fd7288e00bef3172c41f0bb091467 443 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 19 93 3.1E-21 T 23-10-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 TON_1772 199fd7288e00bef3172c41f0bb091467 443 Pfam PF00120 Glutamine synthetase, catalytic domain 101 438 5.4E-128 T 23-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 TON_1822 66c760538d15d9528b379fb3d7303aa9 372 Pfam PF00535 Glycosyl transferase family 2 6 167 2.8E-24 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TON_1822 66c760538d15d9528b379fb3d7303aa9 372 SUPERFAMILY SSF53448 2 252 1.91E-41 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TON_1822 66c760538d15d9528b379fb3d7303aa9 372 Gene3D G3DSA:3.90.550.10 1 225 1.0E-51 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TON_0843 9558217418658fb47c456d75ec030095 68 SUPERFAMILY SSF55008 1 67 9.16E-19 T 23-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 TON_0843 9558217418658fb47c456d75ec030095 68 Pfam PF00403 Heavy-metal-associated domain 5 64 3.0E-15 T 23-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 TON_0843 9558217418658fb47c456d75ec030095 68 Gene3D G3DSA:3.30.70.100 2 68 1.0E-18 T 23-10-2018 TON_1510 f07caf7d086cfd22f49c3cec68d81419 141 Gene3D G3DSA:3.30.70.920 65 141 7.8E-19 T 23-10-2018 TON_1510 f07caf7d086cfd22f49c3cec68d81419 141 SMART SM00344 2 108 1.2E-46 T 23-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 TON_1510 f07caf7d086cfd22f49c3cec68d81419 141 Pfam PF01037 Lrp/AsnC ligand binding domain 68 138 2.4E-13 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain TON_1510 f07caf7d086cfd22f49c3cec68d81419 141 ProSitePatterns PS00519 AsnC-type HTH domain signature. 20 46 - T 23-10-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site TON_1510 f07caf7d086cfd22f49c3cec68d81419 141 Pfam PF13404 AsnC-type helix-turn-helix domain 2 43 5.0E-14 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TON_1510 f07caf7d086cfd22f49c3cec68d81419 141 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 18 29 1.9E-15 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TON_1510 f07caf7d086cfd22f49c3cec68d81419 141 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 29 48 1.9E-15 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TON_1510 f07caf7d086cfd22f49c3cec68d81419 141 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 2 18 1.9E-15 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TON_1510 f07caf7d086cfd22f49c3cec68d81419 141 SUPERFAMILY SSF54909 62 141 9.79E-16 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel TON_1510 f07caf7d086cfd22f49c3cec68d81419 141 Gene3D G3DSA:1.10.10.10 1 52 4.3E-21 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TON_1510 f07caf7d086cfd22f49c3cec68d81419 141 SUPERFAMILY SSF46785 1 62 3.06E-18 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TON_0957 a504d8bcc2dab9f535cd3c6d4725d75f 630 TIGRFAM TIGR00451 unchar_dom_2: uncharacterized domain 2 93 203 5.3E-8 T 23-10-2018 IPR004521 Uncharacterised domain CHP00451 GO:0003723 TON_0957 a504d8bcc2dab9f535cd3c6d4725d75f 630 SMART SM00359 133 207 2.9E-16 T 23-10-2018 IPR002478 PUA domain GO:0003723 TON_0957 a504d8bcc2dab9f535cd3c6d4725d75f 630 Gene3D G3DSA:2.30.130.10 130 207 1.7E-12 T 23-10-2018 IPR036974 PUA domain superfamily GO:0003723 TON_0957 a504d8bcc2dab9f535cd3c6d4725d75f 630 Pfam PF12838 4Fe-4S dicluster domain 575 617 6.9E-9 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TON_0957 a504d8bcc2dab9f535cd3c6d4725d75f 630 Gene3D G3DSA:3.40.50.620 213 467 4.7E-48 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TON_0957 a504d8bcc2dab9f535cd3c6d4725d75f 630 Gene3D G3DSA:3.30.70.20 571 621 1.8E-10 T 23-10-2018 TON_0957 a504d8bcc2dab9f535cd3c6d4725d75f 630 SUPERFAMILY SSF54862 567 622 3.54E-15 T 23-10-2018 TON_0957 a504d8bcc2dab9f535cd3c6d4725d75f 630 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 252 429 4.3E-42 T 23-10-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824 Reactome: R-HSA-196843 TON_0957 a504d8bcc2dab9f535cd3c6d4725d75f 630 SUPERFAMILY SSF52402 223 416 1.37E-42 T 23-10-2018 TON_0957 a504d8bcc2dab9f535cd3c6d4725d75f 630 SUPERFAMILY SSF88697 133 204 4.86E-15 T 23-10-2018 IPR015947 PUA-like superfamily TON_0957 a504d8bcc2dab9f535cd3c6d4725d75f 630 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 606 617 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TON_0957 a504d8bcc2dab9f535cd3c6d4725d75f 630 Pfam PF01472 PUA domain 134 204 2.9E-14 T 23-10-2018 IPR002478 PUA domain GO:0003723 TON_0957 a504d8bcc2dab9f535cd3c6d4725d75f 630 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 575 586 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TON_0266 07cad9f1f7fe9cb53b042ec18726991a 521 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 249 273 5.1E-7 T 23-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_0266 07cad9f1f7fe9cb53b042ec18726991a 521 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 136 155 5.1E-7 T 23-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_0266 07cad9f1f7fe9cb53b042ec18726991a 521 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 397 423 5.1E-7 T 23-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_0266 07cad9f1f7fe9cb53b042ec18726991a 521 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 167 191 5.1E-7 T 23-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_0266 07cad9f1f7fe9cb53b042ec18726991a 521 Pfam PF00361 Proton-conducting membrane transporter 132 438 2.0E-60 T 23-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_1226 95d6b0a48732940369c8d688c3f00e5c 253 Pfam PF04055 Radical SAM superfamily 29 183 2.4E-10 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TON_1226 95d6b0a48732940369c8d688c3f00e5c 253 SUPERFAMILY SSF102114 30 223 1.57E-6 T 23-10-2018 TON_1911 541463f7030a094816e4d956e81abbd9 177 Pfam PF04019 Protein of unknown function (DUF359) 50 171 1.4E-39 T 23-10-2018 IPR007164 Protein of unknown function DUF359 TON_1911 541463f7030a094816e4d956e81abbd9 177 Hamap MF_00590 UPF0218 protein . 6 173 29.952 T 23-10-2018 IPR007164 Protein of unknown function DUF359 TON_1911 541463f7030a094816e4d956e81abbd9 177 PIRSF PIRSF006533 1 175 7.8E-56 T 23-10-2018 IPR007164 Protein of unknown function DUF359 TON_1737 640a713571aea07ac9d171ca4d331aa8 169 Pfam PF03657 Uncharacterised protein family (UPF0113) 7 167 2.5E-12 T 23-10-2018 IPR005155 Ribosome biogenesis factor NIP7-like Reactome: R-HSA-6791226 TON_1737 640a713571aea07ac9d171ca4d331aa8 169 Gene3D G3DSA:3.10.450.220 1 95 1.2E-44 T 23-10-2018 TON_1737 640a713571aea07ac9d171ca4d331aa8 169 Gene3D G3DSA:2.30.130.10 96 167 2.2E-19 T 23-10-2018 IPR036974 PUA domain superfamily GO:0003723 TON_0501 ffac96124cb4627107efea1915af6df6 377 Gene3D G3DSA:3.40.50.2000 183 347 6.3E-140 T 23-10-2018 TON_0501 ffac96124cb4627107efea1915af6df6 377 SUPERFAMILY SSF53756 2 364 8.9E-127 T 23-10-2018 TON_0501 ffac96124cb4627107efea1915af6df6 377 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 25 360 6.7E-124 T 23-10-2018 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 TON_0501 ffac96124cb4627107efea1915af6df6 377 Gene3D G3DSA:3.40.50.2000 6 357 6.3E-140 T 23-10-2018 TON_0501 ffac96124cb4627107efea1915af6df6 377 TIGRFAM TIGR00236 wecB: UDP-N-acetylglucosamine 2-epimerase 3 362 7.2E-135 T 23-10-2018 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 TON_1638 2e0b33f1d59b0b652d289a15d4427ae2 160 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 8 61 2.5E-11 T 23-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 TON_1638 2e0b33f1d59b0b652d289a15d4427ae2 160 Gene3D G3DSA:3.40.50.620 6 153 7.0E-41 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TON_1638 2e0b33f1d59b0b652d289a15d4427ae2 160 SUPERFAMILY SSF52374 3 147 1.44E-19 T 23-10-2018 TON_1638 2e0b33f1d59b0b652d289a15d4427ae2 160 Pfam PF01467 Cytidylyltransferase-like 9 145 1.3E-13 T 23-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 TON_0492 fdfc9a197d64cbf683b7bce877752d1d 495 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 78 103 7.0E-8 T 23-10-2018 TON_0492 fdfc9a197d64cbf683b7bce877752d1d 495 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 238 264 7.0E-8 T 23-10-2018 TON_0492 fdfc9a197d64cbf683b7bce877752d1d 495 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 309 321 7.0E-8 T 23-10-2018 TON_0492 fdfc9a197d64cbf683b7bce877752d1d 495 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 413 432 7.0E-8 T 23-10-2018 TON_0492 fdfc9a197d64cbf683b7bce877752d1d 495 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 216 237 7.0E-8 T 23-10-2018 TON_0492 fdfc9a197d64cbf683b7bce877752d1d 495 Pfam PF00361 Proton-conducting membrane transporter 130 416 7.8E-61 T 23-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_1842 992b5faaa1cf7e52d4b4ffc132e336cb 352 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 254 285 1.6E-6 T 23-10-2018 IPR001451 Hexapeptide repeat TON_1842 992b5faaa1cf7e52d4b4ffc132e336cb 352 TIGRFAM TIGR01208 rmlA_long: glucose-1-phosphate thymidylyltransferase 2 352 5.6E-161 T 23-10-2018 IPR005908 Glucose-1-phosphate thymidylyltransferase, long form TON_1842 992b5faaa1cf7e52d4b4ffc132e336cb 352 Gene3D G3DSA:2.160.10.10 239 351 1.2E-13 T 23-10-2018 TON_1842 992b5faaa1cf7e52d4b4ffc132e336cb 352 SUPERFAMILY SSF53448 1 305 6.34E-75 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TON_1842 992b5faaa1cf7e52d4b4ffc132e336cb 352 Pfam PF00483 Nucleotidyl transferase 2 234 1.7E-50 T 23-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 TON_1842 992b5faaa1cf7e52d4b4ffc132e336cb 352 Gene3D G3DSA:3.90.550.10 1 238 4.5E-67 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TON_1710 4f2e0ce5fdeed53cf46f2aeea17cdd5c 383 TIGRFAM TIGR03812 tyr_de_CO2_Arch: tyrosine decarboxylase MnfA 8 380 6.9E-169 T 23-10-2018 IPR020931 Decarboxylase MfnA, archaea GO:0016831 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 TON_1710 4f2e0ce5fdeed53cf46f2aeea17cdd5c 383 Hamap MF_01610 Probable L-tyrosine/L-aspartate decarboxylase [mfnA]. 14 381 51.578 T 23-10-2018 IPR020931 Decarboxylase MfnA, archaea GO:0016831 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 TON_1710 4f2e0ce5fdeed53cf46f2aeea17cdd5c 383 Gene3D G3DSA:3.90.1150.10 5 374 9.7E-128 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TON_1710 4f2e0ce5fdeed53cf46f2aeea17cdd5c 383 ProSitePatterns PS00392 DDC / GAD / HDC / TyrDC pyridoxal-phosphate attachment site. 224 245 - T 23-10-2018 IPR021115 Pyridoxal-phosphate binding site GO:0016831 TON_1710 4f2e0ce5fdeed53cf46f2aeea17cdd5c 383 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 69 331 1.6E-32 T 23-10-2018 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 TON_1710 4f2e0ce5fdeed53cf46f2aeea17cdd5c 383 Gene3D G3DSA:3.40.640.10 40 290 9.7E-128 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TON_1710 4f2e0ce5fdeed53cf46f2aeea17cdd5c 383 SUPERFAMILY SSF53383 2 382 5.51E-104 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TON_0513 c9e45abb9eb659efe3b9f34a0dd4087f 130 PIRSF PIRSF004966 1 130 2.4E-55 T 23-10-2018 IPR012016 Aconitase X subunit 2, putative TON_0513 c9e45abb9eb659efe3b9f34a0dd4087f 130 Hamap MF_00078 UPF0107 protein . 2 129 33.979 T 23-10-2018 IPR020794 Aconitase X subunit 2, archaeal, putative TON_0513 c9e45abb9eb659efe3b9f34a0dd4087f 130 Gene3D G3DSA:3.50.30.10 1 130 1.0E-50 T 23-10-2018 TON_0513 c9e45abb9eb659efe3b9f34a0dd4087f 130 Pfam PF01989 Protein of unknown function DUF126 24 103 8.4E-36 T 23-10-2018 IPR002840 Aconitase X swivel domain, putative TON_0513 c9e45abb9eb659efe3b9f34a0dd4087f 130 SUPERFAMILY SSF52016 1 128 6.12E-45 T 23-10-2018 TON_1698 7d531964d0f129d9a413ebd050d0d63f 400 SUPERFAMILY SSF53756 36 377 9.42E-21 T 23-10-2018 TON_1698 7d531964d0f129d9a413ebd050d0d63f 400 Gene3D G3DSA:3.40.50.2000 88 181 5.2E-15 T 23-10-2018 TON_1698 7d531964d0f129d9a413ebd050d0d63f 400 Gene3D G3DSA:3.40.50.2000 182 362 5.2E-15 T 23-10-2018 TON_1698 7d531964d0f129d9a413ebd050d0d63f 400 Pfam PF00534 Glycosyl transferases group 1 195 356 2.0E-8 T 23-10-2018 IPR001296 Glycosyl transferase, family 1 TON_0801 4b6d18867fac4684f34241d86aca221b 226 TIGRFAM TIGR00035 asp_race: aspartate racemase 1 224 1.5E-55 T 23-10-2018 IPR004380 Aspartate racemase GO:0006520|GO:0016855 TON_0801 4b6d18867fac4684f34241d86aca221b 226 Pfam PF01177 Asp/Glu/Hydantoin racemase 7 220 1.1E-57 T 23-10-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 TON_0801 4b6d18867fac4684f34241d86aca221b 226 Gene3D G3DSA:3.40.50.1860 102 211 1.2E-79 T 23-10-2018 TON_0801 4b6d18867fac4684f34241d86aca221b 226 SUPERFAMILY SSF53681 1 114 6.1E-30 T 23-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 TON_0801 4b6d18867fac4684f34241d86aca221b 226 SUPERFAMILY SSF53681 116 224 2.4E-26 T 23-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 TON_0801 4b6d18867fac4684f34241d86aca221b 226 Gene3D G3DSA:3.40.50.1860 4 215 1.2E-79 T 23-10-2018 TON_1189 b1117a3be7e02e92dae699feb0e274b5 235 TIGRFAM TIGR02537 arch_flag_Nterm: archaeal flagellin N-terminal-like domain 6 29 6.1E-6 T 23-10-2018 IPR013373 Flagellin/pilin, N-terminal TON_1189 b1117a3be7e02e92dae699feb0e274b5 235 Pfam PF01917 Archaebacterial flagellin 8 221 6.4E-50 T 23-10-2018 IPR002774 Flagellin, archaea GO:0005198|GO:0006928 TON_0103 952ea4a37d380f9d3e0f5f1220f6f2b6 180 Hamap MF_01306_A 30S ribosomal protein S4 [rpsD]. 1 156 34.318 T 23-10-2018 IPR022802 Ribosomal protein S4, archaeal GO:0006412|GO:0019843 TON_0103 952ea4a37d380f9d3e0f5f1220f6f2b6 180 TIGRFAM TIGR01018 uS4_arch: ribosomal protein uS4 1 161 3.0E-76 T 23-10-2018 IPR005710 Ribosomal protein S4/S9, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0103 952ea4a37d380f9d3e0f5f1220f6f2b6 180 SMART SM00363 103 165 2.5E-15 T 23-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0103 952ea4a37d380f9d3e0f5f1220f6f2b6 180 Pfam PF01479 S4 domain 103 148 4.6E-17 T 23-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0103 952ea4a37d380f9d3e0f5f1220f6f2b6 180 ProSitePatterns PS00632 Ribosomal protein S4 signature. 101 125 - T 23-10-2018 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0103 952ea4a37d380f9d3e0f5f1220f6f2b6 180 SUPERFAMILY SSF55174 9 160 6.42E-34 T 23-10-2018 TON_0103 952ea4a37d380f9d3e0f5f1220f6f2b6 180 Gene3D G3DSA:3.10.290.10 104 177 2.1E-17 T 23-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 TON_0103 952ea4a37d380f9d3e0f5f1220f6f2b6 180 SMART SM01390 5 102 5.3E-7 T 23-10-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 TON_1753 006b55b145b0682d9f005787466a4a37 465 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 343 352 - T 23-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TON_1753 006b55b145b0682d9f005787466a4a37 465 SUPERFAMILY SSF52540 81 357 4.56E-89 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_1753 006b55b145b0682d9f005787466a4a37 465 SUPERFAMILY SSF47917 365 422 2.88E-9 T 23-10-2018 TON_1753 006b55b145b0682d9f005787466a4a37 465 Gene3D G3DSA:3.40.50.12240 4 461 3.0E-195 T 23-10-2018 TON_1753 006b55b145b0682d9f005787466a4a37 465 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 11 77 4.3E-13 T 23-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TON_1753 006b55b145b0682d9f005787466a4a37 465 PIRSF PIRSF039114 1 465 6.8E-257 T 23-10-2018 IPR022879 V-type ATP synthase regulatory subunit B/beta Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TON_1753 006b55b145b0682d9f005787466a4a37 465 Hamap MF_00310 V-type ATP synthase beta chain [atpB]. 5 461 62.73 T 23-10-2018 IPR022879 V-type ATP synthase regulatory subunit B/beta Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TON_1753 006b55b145b0682d9f005787466a4a37 465 TIGRFAM TIGR01041 ATP_syn_B_arch: ATP synthase archaeal, B subunit 7 463 1.9E-268 T 23-10-2018 IPR005724 ATPase, A1 complex, beta subunit GO:0015986|GO:0033178|GO:0046933 TON_1753 006b55b145b0682d9f005787466a4a37 465 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 134 352 2.0E-68 T 23-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TON_1502 6133e5c37dc9b75233ce6dcfb573cf8e 315 SUPERFAMILY SSF53633 1 312 5.05E-87 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily TON_1502 6133e5c37dc9b75233ce6dcfb573cf8e 315 PRINTS PR01469 Bacterial carbamate kinase signature 161 180 1.3E-68 T 23-10-2018 TON_1502 6133e5c37dc9b75233ce6dcfb573cf8e 315 PRINTS PR01469 Bacterial carbamate kinase signature 184 202 1.3E-68 T 23-10-2018 TON_1502 6133e5c37dc9b75233ce6dcfb573cf8e 315 PRINTS PR01469 Bacterial carbamate kinase signature 77 95 1.3E-68 T 23-10-2018 TON_1502 6133e5c37dc9b75233ce6dcfb573cf8e 315 PRINTS PR01469 Bacterial carbamate kinase signature 269 284 1.3E-68 T 23-10-2018 TON_1502 6133e5c37dc9b75233ce6dcfb573cf8e 315 PRINTS PR01469 Bacterial carbamate kinase signature 44 63 1.3E-68 T 23-10-2018 TON_1502 6133e5c37dc9b75233ce6dcfb573cf8e 315 PRINTS PR01469 Bacterial carbamate kinase signature 214 229 1.3E-68 T 23-10-2018 TON_1502 6133e5c37dc9b75233ce6dcfb573cf8e 315 PRINTS PR01469 Bacterial carbamate kinase signature 112 131 1.3E-68 T 23-10-2018 TON_1502 6133e5c37dc9b75233ce6dcfb573cf8e 315 Pfam PF00696 Amino acid kinase family 2 295 1.1E-29 T 23-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 TON_1502 6133e5c37dc9b75233ce6dcfb573cf8e 315 PIRSF PIRSF000723 1 314 1.6E-140 T 23-10-2018 IPR003964 Carbamate kinase GO:0006525|GO:0008804 KEGG: 00220+2.7.2.2|KEGG: 00230+2.7.2.2|KEGG: 00910+2.7.2.2 TON_1502 6133e5c37dc9b75233ce6dcfb573cf8e 315 TIGRFAM TIGR00746 arcC: carbamate kinase 2 314 1.0E-144 T 23-10-2018 IPR003964 Carbamate kinase GO:0006525|GO:0008804 KEGG: 00220+2.7.2.2|KEGG: 00230+2.7.2.2|KEGG: 00910+2.7.2.2 TON_1502 6133e5c37dc9b75233ce6dcfb573cf8e 315 Gene3D G3DSA:3.40.1160.10 1 315 8.7E-136 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily TON_1968 ab5765b8c11d18d26e285dfdfa7efb14 179 Pfam PF00857 Isochorismatase family 5 178 2.7E-47 T 23-10-2018 IPR000868 Isochorismatase-like GO:0003824 TON_1968 ab5765b8c11d18d26e285dfdfa7efb14 179 Gene3D G3DSA:3.40.50.850 1 178 6.5E-73 T 23-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 TON_1968 ab5765b8c11d18d26e285dfdfa7efb14 179 SUPERFAMILY SSF52499 4 179 6.41E-56 T 23-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 TON_1080 caa8278b5f5266e25da43fcf0d56340e 602 SUPERFAMILY SSF52540 134 439 4.98E-29 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_1080 caa8278b5f5266e25da43fcf0d56340e 602 SUPERFAMILY SSF88723 2 132 2.39E-15 T 23-10-2018 IPR029060 PIN-like domain superfamily TON_1080 caa8278b5f5266e25da43fcf0d56340e 602 SMART SM00670 2 115 1.5E-20 T 23-10-2018 IPR002716 PIN domain TON_1080 caa8278b5f5266e25da43fcf0d56340e 602 SUPERFAMILY SSF54814 465 520 3.07E-6 T 23-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 TON_1080 caa8278b5f5266e25da43fcf0d56340e 602 Gene3D G3DSA:3.40.50.300 239 425 4.7E-18 T 23-10-2018 TON_1080 caa8278b5f5266e25da43fcf0d56340e 602 Gene3D G3DSA:3.40.50.1010 1 127 2.3E-32 T 23-10-2018 TON_1080 caa8278b5f5266e25da43fcf0d56340e 602 Pfam PF00437 Type II/IV secretion system protein 213 370 4.2E-9 T 23-10-2018 IPR001482 Type II/IV secretion system protein TON_0661 ad765f9b66934b02ed63113c08c2c1a6 161 Pfam PF02441 Flavoprotein 1 156 3.5E-30 T 23-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 TON_0661 ad765f9b66934b02ed63113c08c2c1a6 161 TIGRFAM TIGR00421 ubiX_pad: polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylases 2 160 2.0E-65 T 23-10-2018 IPR004507 Flavin prenyltransferase UbiX-like TON_0661 ad765f9b66934b02ed63113c08c2c1a6 161 Hamap MF_01984 Flavin prenyltransferase UbiX [ubiX]. 1 161 31.329 T 23-10-2018 IPR004507 Flavin prenyltransferase UbiX-like TON_0661 ad765f9b66934b02ed63113c08c2c1a6 161 SUPERFAMILY SSF52507 1 159 1.57E-54 T 23-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 TON_0661 ad765f9b66934b02ed63113c08c2c1a6 161 Gene3D G3DSA:3.40.50.1950 1 161 3.5E-66 T 23-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 TON_0537 4cb96d51024fc5a904d5acf40989ef28 367 SUPERFAMILY SSF54862 221 329 1.67E-11 T 23-10-2018 TON_0537 4cb96d51024fc5a904d5acf40989ef28 367 Pfam PF17179 4Fe-4S dicluster domain 232 326 1.4E-26 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TON_0537 4cb96d51024fc5a904d5acf40989ef28 367 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 233 244 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TON_0537 4cb96d51024fc5a904d5acf40989ef28 367 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 312 323 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TON_1954 8c6253153ccf3cfc77f8026e7be33825 354 Gene3D G3DSA:2.40.50.140 168 347 8.8E-11 T 23-10-2018 TON_1954 8c6253153ccf3cfc77f8026e7be33825 354 SUPERFAMILY SSF50249 183 348 3.26E-16 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold TON_1954 8c6253153ccf3cfc77f8026e7be33825 354 Gene3D G3DSA:2.40.50.140 61 165 2.9E-22 T 23-10-2018 TON_1954 8c6253153ccf3cfc77f8026e7be33825 354 Pfam PF01336 OB-fold nucleic acid binding domain 73 151 9.9E-12 T 23-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 TON_1954 8c6253153ccf3cfc77f8026e7be33825 354 SUPERFAMILY SSF50249 53 175 1.1E-26 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold TON_1954 8c6253153ccf3cfc77f8026e7be33825 354 Pfam PF08646 Replication factor-A C terminal domain 193 297 7.8E-10 T 23-10-2018 IPR013955 Replication factor A, C-terminal TON_0433 122f5a60b73a3739982c184ecf0ad363 209 Gene3D G3DSA:3.40.50.11570 2 209 1.5E-31 T 23-10-2018 TON_0433 122f5a60b73a3739982c184ecf0ad363 209 Pfam PF03192 Pyrococcus protein of unknown function, DUF257 8 206 3.2E-26 T 23-10-2018 IPR005489 Protein of unknown function DUF257 TON_0037 eb80b11e1a4102250f55002c5d707364 280 SUPERFAMILY SSF54631 124 277 9.27E-32 T 23-10-2018 TON_0037 eb80b11e1a4102250f55002c5d707364 280 Pfam PF00571 CBS domain 135 180 3.2E-5 T 23-10-2018 IPR000644 CBS domain TON_0037 eb80b11e1a4102250f55002c5d707364 280 Pfam PF00571 CBS domain 3 54 1.7E-9 T 23-10-2018 IPR000644 CBS domain TON_0037 eb80b11e1a4102250f55002c5d707364 280 Pfam PF00571 CBS domain 67 115 4.0E-12 T 23-10-2018 IPR000644 CBS domain TON_0037 eb80b11e1a4102250f55002c5d707364 280 Pfam PF00571 CBS domain 223 278 9.7E-13 T 23-10-2018 IPR000644 CBS domain TON_0037 eb80b11e1a4102250f55002c5d707364 280 SMART SM00116 69 117 2.6E-9 T 23-10-2018 IPR000644 CBS domain TON_0037 eb80b11e1a4102250f55002c5d707364 280 SMART SM00116 230 278 2.2E-10 T 23-10-2018 IPR000644 CBS domain TON_0037 eb80b11e1a4102250f55002c5d707364 280 SMART SM00116 10 58 4.6E-5 T 23-10-2018 IPR000644 CBS domain TON_0037 eb80b11e1a4102250f55002c5d707364 280 SMART SM00116 135 183 2.2 T 23-10-2018 IPR000644 CBS domain TON_0037 eb80b11e1a4102250f55002c5d707364 280 Gene3D G3DSA:3.10.580.10 1 121 3.2E-41 T 23-10-2018 TON_0037 eb80b11e1a4102250f55002c5d707364 280 SUPERFAMILY SSF54631 1 117 2.15E-29 T 23-10-2018 TON_0037 eb80b11e1a4102250f55002c5d707364 280 Gene3D G3DSA:3.10.580.10 122 280 2.0E-36 T 23-10-2018 TON_1815 b0e28369bf92dfc45c69003c18270ac7 154 Gene3D G3DSA:3.40.50.2020 1 154 2.2E-52 T 23-10-2018 TON_1815 b0e28369bf92dfc45c69003c18270ac7 154 SUPERFAMILY SSF53271 2 147 6.29E-35 T 23-10-2018 IPR029057 Phosphoribosyltransferase-like TON_1815 b0e28369bf92dfc45c69003c18270ac7 154 Pfam PF00156 Phosphoribosyl transferase domain 11 150 7.6E-27 T 23-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 TON_0014 48011c0c8ce95d94df0279108e87a04e 346 Pfam PF12849 PBP superfamily domain 36 273 2.3E-22 T 23-10-2018 IPR024370 PBP domain TON_0014 48011c0c8ce95d94df0279108e87a04e 346 SUPERFAMILY SSF53850 41 282 3.11E-23 T 23-10-2018 TON_0014 48011c0c8ce95d94df0279108e87a04e 346 Gene3D G3DSA:3.40.190.10 43 279 6.0E-75 T 23-10-2018 TON_0014 48011c0c8ce95d94df0279108e87a04e 346 Gene3D G3DSA:3.40.190.10 119 242 6.0E-75 T 23-10-2018 TON_0113 a8362df54c504c1a5bfcd9a2bb87de67 52 Hamap MF_00788 50S ribosomal protein L40e [rpl40e]. 2 47 19.565 T 23-10-2018 IPR023657 Ribosomal protein L40e, archaeal GO:0003735|GO:0005840|GO:0006412 TON_0113 a8362df54c504c1a5bfcd9a2bb87de67 52 SMART SM01377 1 46 3.5E-8 T 23-10-2018 IPR001975 Ribosomal protein L40e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 TON_0113 a8362df54c504c1a5bfcd9a2bb87de67 52 Gene3D G3DSA:2.20.28.70 1 49 1.1E-18 T 23-10-2018 IPR038587 Ribosomal protein L40e superfamily Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 TON_0113 a8362df54c504c1a5bfcd9a2bb87de67 52 SUPERFAMILY SSF57829 2 46 8.24E-16 T 23-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 TON_1518 afa88a3b0c7ba6a846b610d8a8976563 195 SUPERFAMILY SSF52141 7 190 2.06E-62 T 23-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 TON_1518 afa88a3b0c7ba6a846b610d8a8976563 195 Gene3D G3DSA:3.40.470.10 5 193 3.0E-72 T 23-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 TON_1518 afa88a3b0c7ba6a846b610d8a8976563 195 SMART SM00986 31 185 5.5E-38 T 23-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 TON_1518 afa88a3b0c7ba6a846b610d8a8976563 195 SMART SM00987 31 185 5.5E-38 T 23-10-2018 TON_1518 afa88a3b0c7ba6a846b610d8a8976563 195 Pfam PF03167 Uracil DNA glycosylase superfamily 31 184 7.7E-47 T 23-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 TON_1518 afa88a3b0c7ba6a846b610d8a8976563 195 TIGRFAM TIGR00758 UDG_fam4: uracil-DNA glycosylase, family 4 17 191 7.2E-77 T 23-10-2018 IPR005273 Uracil-DNA glycosylase family 4 TON_0948 427d87dc49d779a948db5684eae4640b 597 Hamap MF_00100_A Translation initiation factor IF-2 [infB]. 2 596 43.63 T 23-10-2018 IPR004544 Translation initiation factor aIF-2, archaea GO:0003743|GO:0005525|GO:0005622|GO:0006413 TON_0948 427d87dc49d779a948db5684eae4640b 597 Gene3D G3DSA:2.40.30.10 466 556 3.2E-30 T 23-10-2018 TON_0948 427d87dc49d779a948db5684eae4640b 597 PRINTS PR00315 GTP-binding elongation factor signature 8 21 1.6E-10 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TON_0948 427d87dc49d779a948db5684eae4640b 597 PRINTS PR00315 GTP-binding elongation factor signature 126 135 1.6E-10 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TON_0948 427d87dc49d779a948db5684eae4640b 597 PRINTS PR00315 GTP-binding elongation factor signature 74 84 1.6E-10 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TON_0948 427d87dc49d779a948db5684eae4640b 597 PRINTS PR00315 GTP-binding elongation factor signature 90 101 1.6E-10 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TON_0948 427d87dc49d779a948db5684eae4640b 597 TIGRFAM TIGR00491 aIF-2: translation initiation factor aIF-2 3 594 6.6E-242 T 23-10-2018 IPR004544 Translation initiation factor aIF-2, archaea GO:0003743|GO:0005525|GO:0005622|GO:0006413 TON_0948 427d87dc49d779a948db5684eae4640b 597 SUPERFAMILY SSF50447 465 592 2.29E-24 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily TON_0948 427d87dc49d779a948db5684eae4640b 597 Pfam PF00009 Elongation factor Tu GTP binding domain 8 214 7.2E-33 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TON_0948 427d87dc49d779a948db5684eae4640b 597 Pfam PF03144 Elongation factor Tu domain 2 247 325 1.4E-13 T 23-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 TON_0948 427d87dc49d779a948db5684eae4640b 597 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 8 162 2.4E-20 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 TON_0948 427d87dc49d779a948db5684eae4640b 597 Pfam PF11987 Translation-initiation factor 2 351 446 3.1E-24 T 23-10-2018 IPR023115 Translation initiation factor IF- 2, domain 3 TON_0948 427d87dc49d779a948db5684eae4640b 597 SUPERFAMILY SSF52540 5 288 3.25E-55 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_0948 427d87dc49d779a948db5684eae4640b 597 Pfam PF14578 Elongation factor Tu domain 4 467 553 3.6E-29 T 23-10-2018 IPR029459 Elongation factor Tu-type domain TON_0948 427d87dc49d779a948db5684eae4640b 597 Gene3D G3DSA:3.40.50.300 1 227 3.3E-66 T 23-10-2018 TON_0948 427d87dc49d779a948db5684eae4640b 597 Gene3D G3DSA:3.40.50.10050 349 457 8.3E-37 T 23-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily TON_0948 427d87dc49d779a948db5684eae4640b 597 SUPERFAMILY SSF52156 334 460 9.29E-36 T 23-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily TON_0948 427d87dc49d779a948db5684eae4640b 597 Gene3D G3DSA:2.40.30.10 228 338 1.2E-41 T 23-10-2018 TON_0175 bc685e2d11d3a2bbebb32c10d66a9014 272 Gene3D G3DSA:3.40.50.10700 187 272 2.6E-32 T 23-10-2018 TON_0175 bc685e2d11d3a2bbebb32c10d66a9014 272 SUPERFAMILY SSF142535 1 270 4.97E-86 T 23-10-2018 TON_0175 bc685e2d11d3a2bbebb32c10d66a9014 272 Gene3D G3DSA:3.40.630.50 1 186 4.7E-69 T 23-10-2018 TON_0175 bc685e2d11d3a2bbebb32c10d66a9014 272 Pfam PF04414 D-aminoacyl-tRNA deacylase 70 269 2.0E-66 T 23-10-2018 IPR007508 D-aminoacyl-tRNA deacylase DtdA GO:0016788|GO:0051499 TON_0175 bc685e2d11d3a2bbebb32c10d66a9014 272 Hamap MF_00562 D-aminoacyl-tRNA deacylase [dtdA]. 1 271 35.132 T 23-10-2018 IPR018033 D-aminoacyl-tRNA deacylase, archaea GO:0016788|GO:0019478|GO:0051499 TON_0175 bc685e2d11d3a2bbebb32c10d66a9014 272 PIRSF PIRSF016210 1 272 5.5E-82 T 23-10-2018 IPR018033 D-aminoacyl-tRNA deacylase, archaea GO:0016788|GO:0019478|GO:0051499 TON_1231 f7c7b68d887dce303cdfbd56a0adaeff 198 SUPERFAMILY SSF46785 6 172 7.18E-27 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TON_1231 f7c7b68d887dce303cdfbd56a0adaeff 198 Gene3D G3DSA:1.10.10.10 4 105 1.0E-27 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TON_1231 f7c7b68d887dce303cdfbd56a0adaeff 198 SMART SM00418 9 89 2.0E-17 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TON_1231 f7c7b68d887dce303cdfbd56a0adaeff 198 Pfam PF01022 Bacterial regulatory protein, arsR family 16 61 5.7E-13 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TON_0679 30a2c3ad80c7f676abf4d808516a41f6 294 Hamap MF_00024 Cobalamin biosynthesis protein CbiB [cbiB]. 1 290 77.172 T 23-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 TON_0679 30a2c3ad80c7f676abf4d808516a41f6 294 TIGRFAM TIGR00380 cobD: cobalamin biosynthesis protein CobD 4 288 1.2E-78 T 23-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 TON_0679 30a2c3ad80c7f676abf4d808516a41f6 294 Pfam PF03186 CobD/Cbib protein 8 268 5.7E-82 T 23-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 TON_0757 c373e44c26bd6505cdf2881ca3000a0a 268 Gene3D G3DSA:3.10.270.10 3 267 5.5E-67 T 23-10-2018 TON_0757 c373e44c26bd6505cdf2881ca3000a0a 268 Hamap MF_01527_A GTP cyclohydrolase FolE2 [folE2]. 2 268 26.76 T 23-10-2018 IPR022840 GTP cyclohydrolase MptA GO:0003933 KEGG: 00790+3.5.4.39|MetaCyc: PWY-6797|MetaCyc: PWY-7853 TON_0757 c373e44c26bd6505cdf2881ca3000a0a 268 Pfam PF02649 Type I GTP cyclohydrolase folE2 5 264 4.4E-65 T 23-10-2018 IPR003801 GTP cyclohydrolase FolE2/MptA GO:0003933 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852 TON_0826 22d71930f45fc25ae1cc9da24f02ff15 249 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 35 53 3.6E-15 T 23-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 TON_0826 22d71930f45fc25ae1cc9da24f02ff15 249 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 57 81 3.6E-15 T 23-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 TON_0826 22d71930f45fc25ae1cc9da24f02ff15 249 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 107 129 3.6E-15 T 23-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 TON_0826 22d71930f45fc25ae1cc9da24f02ff15 249 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 195 209 3.6E-15 T 23-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 TON_0826 22d71930f45fc25ae1cc9da24f02ff15 249 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 233 249 3.6E-15 T 23-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 TON_0826 22d71930f45fc25ae1cc9da24f02ff15 249 Gene3D G3DSA:3.70.10.10 2 242 3.2E-79 T 23-10-2018 TON_0826 22d71930f45fc25ae1cc9da24f02ff15 249 Hamap MF_00317 DNA polymerase sliding clamp [pcn]. 3 247 32.853 T 23-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 TON_0826 22d71930f45fc25ae1cc9da24f02ff15 249 ProSitePatterns PS01251 Proliferating cell nuclear antigen signature 1. 35 58 - T 23-10-2018 IPR022659 Proliferating cell nuclear antigen, PCNA, conserved site Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 TON_0826 22d71930f45fc25ae1cc9da24f02ff15 249 Pfam PF00705 Proliferating cell nuclear antigen, N-terminal domain 4 112 3.8E-18 T 23-10-2018 IPR022648 Proliferating cell nuclear antigen, PCNA, N-terminal GO:0003677|GO:0006275 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 TON_0826 22d71930f45fc25ae1cc9da24f02ff15 249 TIGRFAM TIGR00590 pcna: proliferating cell nuclear antigen (pcna) 3 249 2.1E-39 T 23-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 TON_0826 22d71930f45fc25ae1cc9da24f02ff15 249 SUPERFAMILY SSF55979 3 117 1.64E-33 T 23-10-2018 TON_0826 22d71930f45fc25ae1cc9da24f02ff15 249 Pfam PF02747 Proliferating cell nuclear antigen, C-terminal domain 126 245 2.0E-9 T 23-10-2018 IPR022649 Proliferating cell nuclear antigen, PCNA, C-terminal GO:0003677|GO:0006275 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 TON_0826 22d71930f45fc25ae1cc9da24f02ff15 249 SUPERFAMILY SSF55979 125 247 3.59E-31 T 23-10-2018 TON_1057 b054d34a320b5b1c943bd8084644b108 441 SUPERFAMILY SSF52096 6 190 2.59E-31 T 23-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TON_1057 b054d34a320b5b1c943bd8084644b108 441 Pfam PF00574 Clp protease 54 190 3.6E-10 T 23-10-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA TON_1057 b054d34a320b5b1c943bd8084644b108 441 Pfam PF01957 NfeD-like C-terminal, partner-binding 293 439 6.1E-37 T 23-10-2018 IPR002810 NfeD-like, C-terminal domain TON_1057 b054d34a320b5b1c943bd8084644b108 441 SUPERFAMILY SSF141322 371 438 2.88E-16 T 23-10-2018 TON_1057 b054d34a320b5b1c943bd8084644b108 441 Gene3D G3DSA:3.90.226.10 19 243 2.0E-67 T 23-10-2018 TON_1057 b054d34a320b5b1c943bd8084644b108 441 Gene3D G3DSA:2.40.50.140 376 441 1.0E-24 T 23-10-2018 TON_1119 779d181d69d9e7d0712f218188a8dc05 148 SUPERFAMILY SSF102712 2 127 4.97E-23 T 23-10-2018 TON_1119 779d181d69d9e7d0712f218188a8dc05 148 SMART SM00232 2 129 4.3E-10 T 23-10-2018 IPR000555 JAB1/MPN/MOV34 metalloenzyme domain GO:0005515 TON_1119 779d181d69d9e7d0712f218188a8dc05 148 Gene3D G3DSA:3.40.140.10 2 141 1.0E-27 T 23-10-2018 TON_1119 779d181d69d9e7d0712f218188a8dc05 148 Pfam PF14464 Prokaryotic homologs of the JAB domain 16 117 8.1E-16 T 23-10-2018 IPR028090 JAB domain, prokaryotic TON_0407 8bad7aeefc9f07d524a04ff211f4921d 120 PIRSF PIRSF005053 1 120 1.6E-28 T 23-10-2018 IPR010924 DNA-directed RNA polymerase subunit F (Rpo4) TON_0407 8bad7aeefc9f07d524a04ff211f4921d 120 Gene3D G3DSA:1.10.287.420 1 54 1.1E-35 T 23-10-2018 TON_0407 8bad7aeefc9f07d524a04ff211f4921d 120 Pfam PF03874 RNA polymerase Rpb4 11 119 9.2E-7 T 23-10-2018 IPR005574 RNA polymerase subunit RPB4/RPC9 GO:0006352|GO:0030880 TON_0407 8bad7aeefc9f07d524a04ff211f4921d 120 SUPERFAMILY SSF47819 1 115 9.16E-24 T 23-10-2018 IPR010997 HRDC-like superfamily GO:0000166|GO:0003824|GO:0044237 TON_0407 8bad7aeefc9f07d524a04ff211f4921d 120 Gene3D G3DSA:1.10.150.80 55 120 1.4E-26 T 23-10-2018 TON_1490 3a3ab11de66d159af3f31ad2b69fddfc 91 ProSitePatterns PS00150 Acylphosphatase signature 1. 10 20 - T 23-10-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 TON_1490 3a3ab11de66d159af3f31ad2b69fddfc 91 Pfam PF00708 Acylphosphatase 7 88 8.0E-28 T 23-10-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 TON_1490 3a3ab11de66d159af3f31ad2b69fddfc 91 ProSitePatterns PS00151 Acylphosphatase signature 2. 34 50 - T 23-10-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 TON_1490 3a3ab11de66d159af3f31ad2b69fddfc 91 SUPERFAMILY SSF54975 2 89 4.8E-31 T 23-10-2018 IPR036046 Acylphosphatase-like domain superfamily KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 TON_1490 3a3ab11de66d159af3f31ad2b69fddfc 91 Gene3D G3DSA:3.30.70.100 1 91 1.2E-37 T 23-10-2018 TON_1490 3a3ab11de66d159af3f31ad2b69fddfc 91 PRINTS PR00112 Acylphosphatase signature 5 20 5.0E-10 T 23-10-2018 IPR020456 Acylphosphatase GO:0003998 KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 TON_1490 3a3ab11de66d159af3f31ad2b69fddfc 91 PRINTS PR00112 Acylphosphatase signature 26 51 5.0E-10 T 23-10-2018 IPR020456 Acylphosphatase GO:0003998 KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 TON_0785 e2fc24756f03ac6ef5e14b0234caf830 473 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 6 473 3.5E-170 T 23-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TON_0785 e2fc24756f03ac6ef5e14b0234caf830 473 Pfam PF00224 Pyruvate kinase, barrel domain 6 338 2.0E-118 T 23-10-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TON_0785 e2fc24756f03ac6ef5e14b0234caf830 473 PRINTS PR01050 Pyruvate kinase family signature 63 79 5.5E-64 T 23-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TON_0785 e2fc24756f03ac6ef5e14b0234caf830 473 PRINTS PR01050 Pyruvate kinase family signature 218 244 5.5E-64 T 23-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TON_0785 e2fc24756f03ac6ef5e14b0234caf830 473 PRINTS PR01050 Pyruvate kinase family signature 188 202 5.5E-64 T 23-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TON_0785 e2fc24756f03ac6ef5e14b0234caf830 473 PRINTS PR01050 Pyruvate kinase family signature 270 294 5.5E-64 T 23-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TON_0785 e2fc24756f03ac6ef5e14b0234caf830 473 PRINTS PR01050 Pyruvate kinase family signature 295 313 5.5E-64 T 23-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TON_0785 e2fc24756f03ac6ef5e14b0234caf830 473 PRINTS PR01050 Pyruvate kinase family signature 314 330 5.5E-64 T 23-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TON_0785 e2fc24756f03ac6ef5e14b0234caf830 473 PRINTS PR01050 Pyruvate kinase family signature 245 269 5.5E-64 T 23-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TON_0785 e2fc24756f03ac6ef5e14b0234caf830 473 Gene3D G3DSA:2.40.33.10 74 170 3.7E-166 T 23-10-2018 IPR015806 Pyruvate kinase, insert domain superfamily GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TON_0785 e2fc24756f03ac6ef5e14b0234caf830 473 Pfam PF02887 Pyruvate kinase, alpha/beta domain 363 470 7.1E-24 T 23-10-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TON_0785 e2fc24756f03ac6ef5e14b0234caf830 473 SUPERFAMILY SSF52935 324 473 1.16E-31 T 23-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TON_0785 e2fc24756f03ac6ef5e14b0234caf830 473 Gene3D G3DSA:3.20.20.60 7 336 3.7E-166 T 23-10-2018 TON_0785 e2fc24756f03ac6ef5e14b0234caf830 473 SUPERFAMILY SSF51621 4 340 3.49E-93 T 23-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 TON_0785 e2fc24756f03ac6ef5e14b0234caf830 473 SUPERFAMILY SSF50800 75 167 3.84E-24 T 23-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily TON_0785 e2fc24756f03ac6ef5e14b0234caf830 473 Gene3D G3DSA:3.40.1380.20 337 469 3.7E-166 T 23-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TON_1949 a17b149bb6e602244ea906f196b9b41f 355 Pfam PF16575 mRNA cleavage and polyadenylation factor CLP1 P-loop 34 209 2.1E-40 T 23-10-2018 IPR032319 Polyribonucleotide 5'-hydroxyl-kinase Clp1, P-loop domain TON_1949 a17b149bb6e602244ea906f196b9b41f 355 Gene3D G3DSA:3.40.50.300 14 213 1.6E-28 T 23-10-2018 TON_1949 a17b149bb6e602244ea906f196b9b41f 355 SUPERFAMILY SSF52540 8 139 1.04E-12 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_1905 e780cdfc5892ed4b5387ecb5f886223e 328 Pfam PF04055 Radical SAM superfamily 67 252 7.0E-22 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TON_1905 e780cdfc5892ed4b5387ecb5f886223e 328 SUPERFAMILY SSF102114 66 280 1.29E-16 T 23-10-2018 TON_1905 e780cdfc5892ed4b5387ecb5f886223e 328 Hamap MF_01921 S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase [taw1]. 15 316 49.681 T 23-10-2018 IPR023993 S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase, archaea GO:0008033|GO:0016829|GO:0051539 MetaCyc: PWY-7285|MetaCyc: PWY-7286 TON_1905 e780cdfc5892ed4b5387ecb5f886223e 328 Gene3D G3DSA:3.20.20.70 1 328 2.0E-130 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TON_1905 e780cdfc5892ed4b5387ecb5f886223e 328 TIGRFAM TIGR03972 rSAM_TYW1: wyosine biosynthesis protein TYW1 17 314 1.7E-129 T 23-10-2018 IPR023993 S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase, archaea GO:0008033|GO:0016829|GO:0051539 MetaCyc: PWY-7285|MetaCyc: PWY-7286 TON_1905 e780cdfc5892ed4b5387ecb5f886223e 328 Pfam PF08608 Wyosine base formation 254 315 1.4E-22 T 23-10-2018 IPR013917 tRNA wybutosine-synthesis MetaCyc: PWY-7285|MetaCyc: PWY-7286 TON_1040 bc1e0fe233026233b3735d6c450f6478 666 SUPERFAMILY SSF52540 53 627 7.97E-5 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_1040 bc1e0fe233026233b3735d6c450f6478 666 SMART SM00488 26 277 2.5E-79 T 23-10-2018 IPR006554 Helicase-like, DEXD box c2 type GO:0004003|GO:0016818 TON_1040 bc1e0fe233026233b3735d6c450f6478 666 Pfam PF06733 DEAD_2 87 257 5.4E-34 T 23-10-2018 IPR010614 DEAD2 GO:0003677|GO:0004003|GO:0005524 TON_1040 bc1e0fe233026233b3735d6c450f6478 666 SMART SM00487 31 305 9.3E-8 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TON_1040 bc1e0fe233026233b3735d6c450f6478 666 Gene3D G3DSA:1.10.275.40 253 390 8.5E-117 T 23-10-2018 TON_1040 bc1e0fe233026233b3735d6c450f6478 666 Pfam PF13307 Helicase C-terminal domain 467 640 5.3E-37 T 23-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 TON_1040 bc1e0fe233026233b3735d6c450f6478 666 SMART SM00491 485 627 1.1E-45 T 23-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 TON_1040 bc1e0fe233026233b3735d6c450f6478 666 Gene3D G3DSA:3.40.50.300 437 650 1.2E-42 T 23-10-2018 TON_1040 bc1e0fe233026233b3735d6c450f6478 666 TIGRFAM TIGR00604 rad3: DNA repair helicase (rad3) 348 650 1.0E-78 T 23-10-2018 IPR013020 ATP-dependent helicase Rad3/Chl1-like GO:0004003 TON_1040 bc1e0fe233026233b3735d6c450f6478 666 SUPERFAMILY SSF52540 27 250 9.27E-19 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_1040 bc1e0fe233026233b3735d6c450f6478 666 Pfam PF06777 Helical and beta-bridge domain 263 454 2.1E-67 T 23-10-2018 IPR010643 Helical and beta-bridge domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167246|Reactome: R-HSA-2564830|Reactome: R-HSA-427413|Reactome: R-HSA-5696395|Reactome: R-HSA-5696400|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73863|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-77075 TON_1040 bc1e0fe233026233b3735d6c450f6478 666 Gene3D G3DSA:3.40.50.300 43 422 8.5E-117 T 23-10-2018 TON_1040 bc1e0fe233026233b3735d6c450f6478 666 Gene3D G3DSA:1.10.30.20 118 194 8.5E-117 T 23-10-2018 TON_1308 8f9ef10fb66dfd4564691401fa60aae7 111 Pfam PF04458 Protein of unknown function (DUF505) 1 52 1.5E-11 T 23-10-2018 IPR007548 Protein of unknown function DUF505 TON_0286 67ad0e657f78e35ff85f0833d9b12388 813 SUPERFAMILY SSF54975 43 131 7.85E-26 T 23-10-2018 IPR036046 Acylphosphatase-like domain superfamily KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 TON_0286 67ad0e657f78e35ff85f0833d9b12388 813 Gene3D G3DSA:3.30.420.350 529 784 1.4E-102 T 23-10-2018 TON_0286 67ad0e657f78e35ff85f0833d9b12388 813 Gene3D G3DSA:3.90.870.50 49 405 6.5E-144 T 23-10-2018 TON_0286 67ad0e657f78e35ff85f0833d9b12388 813 Gene3D G3DSA:3.30.420.360 426 796 1.4E-102 T 23-10-2018 TON_0286 67ad0e657f78e35ff85f0833d9b12388 813 Pfam PF00814 Glycoprotease family 646 779 8.5E-6 T 23-10-2018 IPR000905 Gcp-like domain TON_0286 67ad0e657f78e35ff85f0833d9b12388 813 TIGRFAM TIGR00143 hypF: carbamoyltransferase HypF 50 796 5.3E-262 T 23-10-2018 IPR004421 Carbamoyltransferase, HypF-type GO:0016743|GO:0046872|GO:0046944 TON_0286 67ad0e657f78e35ff85f0833d9b12388 813 Pfam PF00708 Acylphosphatase 47 130 6.8E-23 T 23-10-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 TON_0286 67ad0e657f78e35ff85f0833d9b12388 813 SUPERFAMILY SSF53067 443 778 4.21E-8 T 23-10-2018 TON_0286 67ad0e657f78e35ff85f0833d9b12388 813 Pfam PF01300 Telomere recombination 251 426 3.8E-47 T 23-10-2018 IPR006070 YrdC-like domain GO:0003725 TON_0286 67ad0e657f78e35ff85f0833d9b12388 813 Gene3D G3DSA:3.30.110.120 295 414 6.5E-144 T 23-10-2018 TON_0286 67ad0e657f78e35ff85f0833d9b12388 813 Pfam PF07503 HypF finger 201 234 4.5E-15 T 23-10-2018 IPR011125 Zinc finger, HypF-type GO:0008270 TON_0286 67ad0e657f78e35ff85f0833d9b12388 813 Pfam PF07503 HypF finger 151 184 1.7E-16 T 23-10-2018 IPR011125 Zinc finger, HypF-type GO:0008270 TON_0286 67ad0e657f78e35ff85f0833d9b12388 813 SUPERFAMILY SSF55821 218 433 4.58E-46 T 23-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily TON_0286 67ad0e657f78e35ff85f0833d9b12388 813 PIRSF PIRSF006256 42 806 5.8E-283 T 23-10-2018 IPR004421 Carbamoyltransferase, HypF-type GO:0016743|GO:0046872|GO:0046944 TON_1107 23fecf77e93d1d75a37f864fe16c7a01 228 SUPERFAMILY SSF55909 3 226 3.53E-75 T 23-10-2018 TON_1107 23fecf77e93d1d75a37f864fe16c7a01 228 Pfam PF01912 eIF-6 family 5 206 1.1E-70 T 23-10-2018 IPR002769 Translation initiation factor IF6 GO:0042256|GO:0043022 TON_1107 23fecf77e93d1d75a37f864fe16c7a01 228 PIRSF PIRSF006413 2 228 3.0E-80 T 23-10-2018 IPR002769 Translation initiation factor IF6 GO:0042256|GO:0043022 TON_1107 23fecf77e93d1d75a37f864fe16c7a01 228 TIGRFAM TIGR00323 eIF-6: putative translation initiation factor eIF-6 6 226 9.1E-65 T 23-10-2018 IPR002769 Translation initiation factor IF6 GO:0042256|GO:0043022 TON_1107 23fecf77e93d1d75a37f864fe16c7a01 228 Gene3D G3DSA:3.75.10.10 1 227 1.1E-80 T 23-10-2018 TON_1107 23fecf77e93d1d75a37f864fe16c7a01 228 Hamap MF_00032 Translation initiation factor 6 [eif6]. 1 228 98.958 T 23-10-2018 IPR002769 Translation initiation factor IF6 GO:0042256|GO:0043022 TON_1107 23fecf77e93d1d75a37f864fe16c7a01 228 SMART SM00654 4 206 2.0E-103 T 23-10-2018 IPR002769 Translation initiation factor IF6 GO:0042256|GO:0043022 TON_1558 be2bfad1822e3dfedb6a6607b93b98f0 70 Pfam PF01938 TRAM domain 14 70 6.1E-16 T 23-10-2018 IPR002792 TRAM domain TON_1558 be2bfad1822e3dfedb6a6607b93b98f0 70 SUPERFAMILY SSF50249 10 70 1.26E-16 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold TON_1558 be2bfad1822e3dfedb6a6607b93b98f0 70 Gene3D G3DSA:2.40.50.140 5 70 1.8E-25 T 23-10-2018 TON_1752 bab1e9a8d86f765f0cf20ea3fcb183f1 585 Gene3D G3DSA:3.40.50.300 70 434 5.2E-185 T 23-10-2018 TON_1752 bab1e9a8d86f765f0cf20ea3fcb183f1 585 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 4 66 2.0E-15 T 23-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TON_1752 bab1e9a8d86f765f0cf20ea3fcb183f1 585 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 211 434 2.5E-92 T 23-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TON_1752 bab1e9a8d86f765f0cf20ea3fcb183f1 585 SUPERFAMILY SSF52540 162 440 4.83E-86 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_1752 bab1e9a8d86f765f0cf20ea3fcb183f1 585 Gene3D G3DSA:1.10.1140.10 435 585 4.3E-61 T 23-10-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TON_1752 bab1e9a8d86f765f0cf20ea3fcb183f1 585 SUPERFAMILY SSF50615 1 68 2.88E-13 T 23-10-2018 IPR036121 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TON_1752 bab1e9a8d86f765f0cf20ea3fcb183f1 585 TIGRFAM TIGR01043 ATP_syn_A_arch: ATP synthase archaeal, A subunit 1 580 0.0 T 23-10-2018 IPR005726 ATP synthase alpha chain, archaea GO:0015986|GO:0033178|GO:0046961 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TON_1752 bab1e9a8d86f765f0cf20ea3fcb183f1 585 Gene3D G3DSA:2.40.30.20 1 69 2.3E-30 T 23-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TON_1752 bab1e9a8d86f765f0cf20ea3fcb183f1 585 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 425 434 - T 23-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TON_1752 bab1e9a8d86f765f0cf20ea3fcb183f1 585 Gene3D G3DSA:2.40.50.100 113 184 5.2E-185 T 23-10-2018 TON_1752 bab1e9a8d86f765f0cf20ea3fcb183f1 585 Hamap MF_00309 V-type ATP synthase alpha chain [atpA]. 1 583 55.057 T 23-10-2018 IPR022878 V-type ATP synthase catalytic alpha chain GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TON_1752 bab1e9a8d86f765f0cf20ea3fcb183f1 585 Pfam PF16886 ATPsynthase alpha/beta subunit N-term extension 82 202 4.5E-47 T 23-10-2018 IPR031686 ATPsynthase alpha/beta subunit, N-terminal extension KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TON_1752 bab1e9a8d86f765f0cf20ea3fcb183f1 585 SUPERFAMILY SSF47917 447 552 1.1E-27 T 23-10-2018 TON_1752 bab1e9a8d86f765f0cf20ea3fcb183f1 585 SMART SM00382 223 411 0.0029 T 23-10-2018 IPR003593 AAA+ ATPase domain TON_0938 ed2f2edf9c793e9d496d87236d37e6ad 350 SUPERFAMILY SSF55031 156 259 1.94E-11 T 23-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain TON_0938 ed2f2edf9c793e9d496d87236d37e6ad 350 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 87 124 - T 23-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 TON_0938 ed2f2edf9c793e9d496d87236d37e6ad 350 Gene3D G3DSA:3.30.70.360 155 264 3.3E-63 T 23-10-2018 TON_0938 ed2f2edf9c793e9d496d87236d37e6ad 350 Gene3D G3DSA:3.40.630.10 14 336 3.3E-63 T 23-10-2018 TON_0938 ed2f2edf9c793e9d496d87236d37e6ad 350 Pfam PF01546 Peptidase family M20/M25/M40 64 343 1.8E-26 T 23-10-2018 IPR002933 Peptidase M20 GO:0016787 TON_0938 ed2f2edf9c793e9d496d87236d37e6ad 350 SUPERFAMILY SSF53187 8 343 8.0E-43 T 23-10-2018 TON_0938 ed2f2edf9c793e9d496d87236d37e6ad 350 Pfam PF07687 Peptidase dimerisation domain 152 257 4.8E-7 T 23-10-2018 IPR011650 Peptidase M20, dimerisation domain TON_1102 05b12cc7ed0a2add88408031bc843644 112 Hamap MF_00026 DNA-binding protein . 3 112 16.074 T 23-10-2018 IPR022889 DNA-binding protein, archaeal TON_1102 05b12cc7ed0a2add88408031bc843644 112 SUPERFAMILY SSF46950 8 111 6.93E-28 T 23-10-2018 IPR036883 PDCD5-like superfamily GO:0003677 TON_1102 05b12cc7ed0a2add88408031bc843644 112 PIRSF PIRSF015730 1 112 5.0E-35 T 23-10-2018 IPR002836 PDCD5-like GO:0003677 TON_1102 05b12cc7ed0a2add88408031bc843644 112 Pfam PF01984 Double-stranded DNA-binding domain 8 111 7.1E-27 T 23-10-2018 IPR002836 PDCD5-like GO:0003677 TON_1102 05b12cc7ed0a2add88408031bc843644 112 Gene3D G3DSA:1.10.8.140 31 112 5.0E-27 T 23-10-2018 IPR036883 PDCD5-like superfamily GO:0003677 TON_0036 f723642a646cb2259c4ffb5eb02a9ce5 333 PIRSF PIRSF036497 1 332 4.1E-91 T 23-10-2018 IPR022697 Homoserine dehydrogenase lacking ACT domain GO:0004412 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 TON_0036 f723642a646cb2259c4ffb5eb02a9ce5 333 Gene3D G3DSA:3.40.50.720 6 326 2.3E-96 T 23-10-2018 TON_0036 f723642a646cb2259c4ffb5eb02a9ce5 333 Pfam PF00742 Homoserine dehydrogenase 155 326 6.2E-51 T 23-10-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 TON_0036 f723642a646cb2259c4ffb5eb02a9ce5 333 SUPERFAMILY SSF51735 3 176 9.87E-31 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TON_0036 f723642a646cb2259c4ffb5eb02a9ce5 333 SUPERFAMILY SSF55347 155 313 4.51E-40 T 23-10-2018 TON_0036 f723642a646cb2259c4ffb5eb02a9ce5 333 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 200 222 - T 23-10-2018 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 TON_0036 f723642a646cb2259c4ffb5eb02a9ce5 333 Gene3D G3DSA:3.30.360.10 166 309 2.3E-96 T 23-10-2018 TON_0036 f723642a646cb2259c4ffb5eb02a9ce5 333 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 9 145 1.6E-8 T 23-10-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 TON_0391 7bea39522d33991ab16f9f1c7191a09b 305 Pfam PF00005 ABC transporter 17 167 1.3E-29 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TON_0391 7bea39522d33991ab16f9f1c7191a09b 305 SUPERFAMILY SSF52540 2 230 1.74E-57 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_0391 7bea39522d33991ab16f9f1c7191a09b 305 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TON_0391 7bea39522d33991ab16f9f1c7191a09b 305 SMART SM00382 26 217 2.4E-11 T 23-10-2018 IPR003593 AAA+ ATPase domain TON_0391 7bea39522d33991ab16f9f1c7191a09b 305 Gene3D G3DSA:3.40.50.300 1 238 2.6E-59 T 23-10-2018 TON_1955 d46f62cf21496aa944c5c090fa5b9ae3 195 SUPERFAMILY SSF46785 3 81 1.63E-13 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TON_1955 d46f62cf21496aa944c5c090fa5b9ae3 195 PIRSF PIRSF019345 2 195 9.1E-47 T 23-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 TON_1955 d46f62cf21496aa944c5c090fa5b9ae3 195 SUPERFAMILY SSF46785 85 152 3.53E-15 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TON_1955 d46f62cf21496aa944c5c090fa5b9ae3 195 Gene3D G3DSA:1.10.10.10 83 170 2.2E-12 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TON_1955 d46f62cf21496aa944c5c090fa5b9ae3 195 Gene3D G3DSA:1.10.10.10 2 82 1.3E-11 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TON_1955 d46f62cf21496aa944c5c090fa5b9ae3 195 TIGRFAM TIGR00281 TIGR00281: segregation and condensation protein B 7 175 1.4E-31 T 23-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 TON_1955 d46f62cf21496aa944c5c090fa5b9ae3 195 Pfam PF04079 Segregation and condensation complex subunit ScpB 9 154 1.9E-35 T 23-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 TON_0750 0fc7323116343ed9b2071c27420dae7c 76 Gene3D G3DSA:3.10.20.30 1 76 7.3E-15 T 23-10-2018 IPR012675 Beta-grasp domain superfamily TON_0750 0fc7323116343ed9b2071c27420dae7c 76 SUPERFAMILY SSF54285 1 76 1.03E-10 T 23-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp TON_0750 0fc7323116343ed9b2071c27420dae7c 76 Pfam PF02597 ThiS family 12 76 2.1E-9 T 23-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 TON_1709 341bb25658c01c5edb9366c74e8a5780 287 Pfam PF16916 Dimerisation domain of Zinc Transporter 208 281 1.4E-22 T 23-10-2018 IPR027470 Cation efflux protein, cytoplasmic domain TON_1709 341bb25658c01c5edb9366c74e8a5780 287 Gene3D G3DSA:3.30.70.1350 208 283 4.1E-21 T 23-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 TON_1709 341bb25658c01c5edb9366c74e8a5780 287 SUPERFAMILY SSF160240 206 281 6.54E-22 T 23-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 TON_1709 341bb25658c01c5edb9366c74e8a5780 287 Gene3D G3DSA:1.20.1510.10 5 201 2.5E-62 T 23-10-2018 IPR027469 Cation efflux transmembrane domain superfamily TON_1709 341bb25658c01c5edb9366c74e8a5780 287 Pfam PF01545 Cation efflux family 9 201 5.3E-47 T 23-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 TON_1709 341bb25658c01c5edb9366c74e8a5780 287 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 7 282 2.3E-84 T 23-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 TON_1709 341bb25658c01c5edb9366c74e8a5780 287 SUPERFAMILY SSF161111 5 203 1.1E-56 T 23-10-2018 IPR027469 Cation efflux transmembrane domain superfamily TON_1194 9307cad9910adf370fee686bd835e06a 408 SUPERFAMILY SSF58104 103 392 8.24E-59 T 23-10-2018 TON_1194 9307cad9910adf370fee686bd835e06a 408 SMART SM00283 129 404 5.3E-47 T 23-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TON_1194 9307cad9910adf370fee686bd835e06a 408 Gene3D G3DSA:1.10.287.950 92 404 2.3E-57 T 23-10-2018 TON_1194 9307cad9910adf370fee686bd835e06a 408 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 174 353 2.8E-38 T 23-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TON_0559 db3d33ec5fe6eda6bd442f7ab1dfdc4b 205 Pfam PF01997 Translin family 21 181 1.2E-11 T 23-10-2018 IPR002848 Translin family GO:0043565 Reactome: R-HSA-426486 TON_0559 db3d33ec5fe6eda6bd442f7ab1dfdc4b 205 SUPERFAMILY SSF74784 3 182 6.15E-37 T 23-10-2018 IPR036081 Translin superfamily GO:0043565 Reactome: R-HSA-426486 TON_0559 db3d33ec5fe6eda6bd442f7ab1dfdc4b 205 Gene3D G3DSA:1.20.58.2140 3 201 2.4E-65 T 23-10-2018 TON_1067 519ac31e8fb0ebe87cb591d091b837b7 280 SUPERFAMILY SSF63992 1 274 1.96E-84 T 23-10-2018 IPR036177 Peptidase M55, D-aminopeptidase superfamily TON_1067 519ac31e8fb0ebe87cb591d091b837b7 280 PIRSF PIRSF015853 1 277 2.5E-99 T 23-10-2018 IPR007035 Peptidase M55, D-aminopeptidase TON_1067 519ac31e8fb0ebe87cb591d091b837b7 280 Gene3D G3DSA:3.30.1360.130 118 264 2.8E-81 T 23-10-2018 TON_1067 519ac31e8fb0ebe87cb591d091b837b7 280 Gene3D G3DSA:3.40.50.10780 1 217 2.8E-81 T 23-10-2018 IPR027476 D-aminopeptidase, N-terminal TON_1067 519ac31e8fb0ebe87cb591d091b837b7 280 Pfam PF04951 D-aminopeptidase 1 265 1.3E-85 T 23-10-2018 IPR007035 Peptidase M55, D-aminopeptidase TON_1644 06409828f953bfb05c2ee241be39c364 415 SUPERFAMILY SSF46785 297 401 6.17E-31 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TON_1644 06409828f953bfb05c2ee241be39c364 415 Gene3D G3DSA:1.10.10.10 304 405 1.4E-33 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TON_1644 06409828f953bfb05c2ee241be39c364 415 SMART SM01074 312 393 8.3E-36 T 23-10-2018 IPR015163 Cdc6, C-terminal Reactome: R-HSA-176187|Reactome: R-HSA-539107|Reactome: R-HSA-68689|Reactome: R-HSA-68827|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962 TON_1644 06409828f953bfb05c2ee241be39c364 415 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 61 204 4.6E-9 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TON_1644 06409828f953bfb05c2ee241be39c364 415 Hamap MF_01407 ORC1-type DNA replication protein. 12 394 34.249 T 23-10-2018 IPR014277 Orc1/Cdc6-type DNA replication protein, archaea TON_1644 06409828f953bfb05c2ee241be39c364 415 SUPERFAMILY SSF52540 19 291 8.99E-56 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_1644 06409828f953bfb05c2ee241be39c364 415 Gene3D G3DSA:1.10.8.60 19 295 5.5E-110 T 23-10-2018 TON_1644 06409828f953bfb05c2ee241be39c364 415 TIGRFAM TIGR02928 TIGR02928: orc1/cdc6 family replication initiation protein 19 383 9.8E-151 T 23-10-2018 IPR014277 Orc1/Cdc6-type DNA replication protein, archaea TON_1644 06409828f953bfb05c2ee241be39c364 415 Pfam PF09079 CDC6, C terminal winged helix domain 312 391 2.1E-26 T 23-10-2018 IPR015163 Cdc6, C-terminal Reactome: R-HSA-176187|Reactome: R-HSA-539107|Reactome: R-HSA-68689|Reactome: R-HSA-68827|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962 TON_1644 06409828f953bfb05c2ee241be39c364 415 SMART SM00382 57 218 1.5E-11 T 23-10-2018 IPR003593 AAA+ ATPase domain TON_1644 06409828f953bfb05c2ee241be39c364 415 Gene3D G3DSA:3.40.50.300 35 216 5.5E-110 T 23-10-2018 TON_0696 eddc379f0f009b434516f85371c54abb 416 Gene3D G3DSA:1.10.3210.10 3 289 2.1E-84 T 23-10-2018 TON_0696 eddc379f0f009b434516f85371c54abb 416 SMART SM00471 48 188 1.3E-12 T 23-10-2018 IPR003607 HD/PDEase domain TON_0696 eddc379f0f009b434516f85371c54abb 416 Pfam PF01966 HD domain 52 180 1.7E-15 T 23-10-2018 IPR006674 HD domain TON_0696 eddc379f0f009b434516f85371c54abb 416 SUPERFAMILY SSF109604 3 412 1.65E-90 T 23-10-2018 TON_0208 8fa98a2b36baea6cf7280703c9f0f3aa 235 PIRSF PIRSF016933 4 224 1.1E-32 T 23-10-2018 IPR023596 Peptidase PrsW, archaeal/bacterial GO:0008233 TON_0208 8fa98a2b36baea6cf7280703c9f0f3aa 235 Pfam PF13367 Protease prsW family 31 204 4.4E-31 T 23-10-2018 IPR026898 Protease PrsW GO:0008233 TON_1480 3b3baad14940e13270c31facf94bcff0 105 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 83 94 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TON_1480 3b3baad14940e13270c31facf94bcff0 105 TIGRFAM TIGR02179 PorD_KorD: 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate family 28 104 7.3E-34 T 23-10-2018 IPR011898 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate GO:0016625|GO:0051539 TON_1480 3b3baad14940e13270c31facf94bcff0 105 Gene3D G3DSA:3.30.70.20 7 105 2.5E-15 T 23-10-2018 TON_1480 3b3baad14940e13270c31facf94bcff0 105 Pfam PF14697 4Fe-4S dicluster domain 48 100 5.7E-11 T 23-10-2018 TON_1480 3b3baad14940e13270c31facf94bcff0 105 SUPERFAMILY SSF54862 27 103 1.97E-23 T 23-10-2018 TON_1690 a5f8162462e6cb794611bdbf1cca33a7 200 ProSitePatterns PS01333 Pyrrolidone-carboxylate peptidase glutamic acid active site. 67 83 - T 23-10-2018 IPR033693 Pyroglutamyl peptidase I, Glu active site MetaCyc: PWY-7942 TON_1690 a5f8162462e6cb794611bdbf1cca33a7 200 TIGRFAM TIGR00504 pyro_pdase: pyroglutamyl-peptidase I 2 198 3.0E-78 T 23-10-2018 IPR029762 Pyroglutamyl peptidase I, bacterial-type GO:0005829|GO:0006508|GO:0008234|GO:0016920 MetaCyc: PWY-7942 TON_1690 a5f8162462e6cb794611bdbf1cca33a7 200 SUPERFAMILY SSF53182 1 198 1.7E-72 T 23-10-2018 IPR036440 Peptidase C15, pyroglutamyl peptidase I-like superfamily MetaCyc: PWY-7942 TON_1690 a5f8162462e6cb794611bdbf1cca33a7 200 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 3 26 6.3E-44 T 23-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 TON_1690 a5f8162462e6cb794611bdbf1cca33a7 200 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 78 98 6.3E-44 T 23-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 TON_1690 a5f8162462e6cb794611bdbf1cca33a7 200 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 160 172 6.3E-44 T 23-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 TON_1690 a5f8162462e6cb794611bdbf1cca33a7 200 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 60 72 6.3E-44 T 23-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 TON_1690 a5f8162462e6cb794611bdbf1cca33a7 200 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 130 146 6.3E-44 T 23-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 TON_1690 a5f8162462e6cb794611bdbf1cca33a7 200 Pfam PF01470 Pyroglutamyl peptidase 1 198 8.5E-78 T 23-10-2018 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like MetaCyc: PWY-7942 TON_1690 a5f8162462e6cb794611bdbf1cca33a7 200 Gene3D G3DSA:3.40.630.20 1 200 2.4E-78 T 23-10-2018 IPR036440 Peptidase C15, pyroglutamyl peptidase I-like superfamily MetaCyc: PWY-7942 TON_1690 a5f8162462e6cb794611bdbf1cca33a7 200 ProSitePatterns PS01334 Pyrrolidone-carboxylate peptidase cysteine active site. 128 142 - T 23-10-2018 IPR033694 Pyroglutamyl peptidase I, Cys active site MetaCyc: PWY-7942 TON_1690 a5f8162462e6cb794611bdbf1cca33a7 200 Hamap MF_00417 Pyrrolidone-carboxylate peptidase [pcp]. 1 198 38.772 T 23-10-2018 IPR029762 Pyroglutamyl peptidase I, bacterial-type GO:0005829|GO:0006508|GO:0008234|GO:0016920 MetaCyc: PWY-7942 TON_1690 a5f8162462e6cb794611bdbf1cca33a7 200 PIRSF PIRSF015592 1 200 5.5E-80 T 23-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 TON_0871 d725a980314209cd423de166b4e17281 174 Pfam PF02915 Rubrerythrin 22 157 2.0E-31 T 23-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 TON_0871 d725a980314209cd423de166b4e17281 174 SUPERFAMILY SSF47240 14 163 2.5E-29 T 23-10-2018 IPR009078 Ferritin-like superfamily TON_0871 d725a980314209cd423de166b4e17281 174 Gene3D G3DSA:1.20.1260.10 12 161 9.7E-48 T 23-10-2018 IPR012347 Ferritin-like TON_1120 5c56b5d2c72679164eaa5c5dfd396f97 244 SUPERFAMILY SSF52540 1 112 1.1E-10 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_1120 5c56b5d2c72679164eaa5c5dfd396f97 244 Gene3D G3DSA:3.40.50.300 1 157 4.5E-26 T 23-10-2018 TON_1120 5c56b5d2c72679164eaa5c5dfd396f97 244 Pfam PF04060 Putative Fe-S cluster 160 191 1.4E-8 T 23-10-2018 IPR007202 4Fe-4S domain GO:0051536 TON_1120 5c56b5d2c72679164eaa5c5dfd396f97 244 Gene3D G3DSA:3.20.20.20 158 221 5.5E-6 T 23-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TON_1120 5c56b5d2c72679164eaa5c5dfd396f97 244 Pfam PF03205 Molybdopterin guanine dinucleotide synthesis protein B 4 110 1.4E-16 T 23-10-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 TON_1410 4eff4877a5380b440fcc6d76ef76dfba 308 Pfam PF13353 4Fe-4S single cluster domain 19 106 6.0E-9 T 23-10-2018 TON_1410 4eff4877a5380b440fcc6d76ef76dfba 308 Hamap MF_01225_A GTP 3',8-cyclase [moaA]. 3 308 42.616 T 23-10-2018 IPR013485 Molybdenum cofactor biosynthesis protein A, archaea GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823 TON_1410 4eff4877a5380b440fcc6d76ef76dfba 308 SMART SM00729 12 228 1.2E-16 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TON_1410 4eff4877a5380b440fcc6d76ef76dfba 308 Pfam PF04055 Radical SAM superfamily 16 172 2.0E-31 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TON_1410 4eff4877a5380b440fcc6d76ef76dfba 308 SUPERFAMILY SSF102114 4 299 6.15E-66 T 23-10-2018 TON_1410 4eff4877a5380b440fcc6d76ef76dfba 308 Gene3D G3DSA:3.20.20.70 1 306 1.8E-73 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TON_1410 4eff4877a5380b440fcc6d76ef76dfba 308 Pfam PF06463 Molybdenum Cofactor Synthesis C 180 307 1.2E-22 T 23-10-2018 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TON_1410 4eff4877a5380b440fcc6d76ef76dfba 308 TIGRFAM TIGR02668 moaA_archaeal: probable molybdenum cofactor biosynthesis protein A 3 308 3.5E-124 T 23-10-2018 IPR013485 Molybdenum cofactor biosynthesis protein A, archaea GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823 TON_1104 fac371394c13555c0a418e5cb6918b45 138 SUPERFAMILY SSF75471 5 101 4.58E-17 T 23-10-2018 IPR035920 YhbY-like superfamily TON_1104 fac371394c13555c0a418e5cb6918b45 138 Pfam PF01985 CRS1 / YhbY (CRM) domain 5 92 8.5E-12 T 23-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 TON_1104 fac371394c13555c0a418e5cb6918b45 138 ProDom PD010559 RNA-BINDING YHBY UPF0044 PREDICTED RNA RIBOSOMAL CONTAINING KH BINDING DOMAIN 11 95 1.0E-36 T 23-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 TON_1104 fac371394c13555c0a418e5cb6918b45 138 SMART SM01103 5 92 1.4E-24 T 23-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 TON_1104 fac371394c13555c0a418e5cb6918b45 138 Gene3D G3DSA:3.30.110.60 5 112 7.9E-21 T 23-10-2018 IPR035920 YhbY-like superfamily TON_1008 b383fb70ba5bf06ee061226a19f7a655 383 Pfam PF02568 Thiamine biosynthesis protein (ThiI) 180 371 5.1E-65 T 23-10-2018 IPR020536 Thil, AANH domain GO:0004810 KEGG: 00730+2.8.1.4 TON_1008 b383fb70ba5bf06ee061226a19f7a655 383 Hamap MF_00021 tRNA sulfurtransferase [thiI]. 1 383 127.524 T 23-10-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 KEGG: 00730+2.8.1.4 TON_1008 b383fb70ba5bf06ee061226a19f7a655 383 Gene3D G3DSA:3.30.70.1510 4 86 1.3E-32 T 23-10-2018 TON_1008 b383fb70ba5bf06ee061226a19f7a655 383 Gene3D G3DSA:3.40.50.620 180 378 1.0E-63 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TON_1008 b383fb70ba5bf06ee061226a19f7a655 383 SUPERFAMILY SSF143437 4 178 4.19E-47 T 23-10-2018 TON_1008 b383fb70ba5bf06ee061226a19f7a655 383 SUPERFAMILY SSF52402 180 339 1.37E-49 T 23-10-2018 TON_1008 b383fb70ba5bf06ee061226a19f7a655 383 Pfam PF02926 THUMP domain 31 170 2.1E-25 T 23-10-2018 IPR004114 THUMP domain GO:0003723 TON_1008 b383fb70ba5bf06ee061226a19f7a655 383 TIGRFAM TIGR00342 TIGR00342: tRNA sulfurtransferase ThiI 7 368 4.1E-105 T 23-10-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 KEGG: 00730+2.8.1.4 TON_1008 b383fb70ba5bf06ee061226a19f7a655 383 SMART SM00981 76 170 4.0E-17 T 23-10-2018 IPR004114 THUMP domain GO:0003723 TON_1008 b383fb70ba5bf06ee061226a19f7a655 383 Gene3D G3DSA:3.30.2300.10 87 168 1.2E-28 T 23-10-2018 TON_0780 950989e4a09979d5d77fee2d6b5c2897 224 Pfam PF00406 Adenylate kinase 5 188 6.1E-43 T 23-10-2018 TON_0780 950989e4a09979d5d77fee2d6b5c2897 224 SUPERFAMILY SSF52540 1 212 1.3E-40 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_0780 950989e4a09979d5d77fee2d6b5c2897 224 Pfam PF05191 Adenylate kinase, active site lid 125 160 2.5E-18 T 23-10-2018 IPR007862 Adenylate kinase, active site lid domain GO:0004017 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 TON_0780 950989e4a09979d5d77fee2d6b5c2897 224 Hamap MF_00235 Adenylate kinase [adk]. 1 211 45.866 T 23-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 TON_0780 950989e4a09979d5d77fee2d6b5c2897 224 Gene3D G3DSA:3.40.50.300 1 220 3.7E-77 T 23-10-2018 TON_0780 950989e4a09979d5d77fee2d6b5c2897 224 ProSitePatterns PS00113 Adenylate kinase signature. 79 90 - T 23-10-2018 IPR033690 Adenylate kinase, conserved site KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 TON_0780 950989e4a09979d5d77fee2d6b5c2897 224 PRINTS PR00094 Adenylate kinase signature 32 46 3.5E-29 T 23-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 TON_0780 950989e4a09979d5d77fee2d6b5c2897 224 PRINTS PR00094 Adenylate kinase signature 175 189 3.5E-29 T 23-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 TON_0780 950989e4a09979d5d77fee2d6b5c2897 224 PRINTS PR00094 Adenylate kinase signature 79 95 3.5E-29 T 23-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 TON_0780 950989e4a09979d5d77fee2d6b5c2897 224 PRINTS PR00094 Adenylate kinase signature 4 17 3.5E-29 T 23-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 TON_0780 950989e4a09979d5d77fee2d6b5c2897 224 PRINTS PR00094 Adenylate kinase signature 158 173 3.5E-29 T 23-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 TON_0780 950989e4a09979d5d77fee2d6b5c2897 224 TIGRFAM TIGR01351 adk: adenylate kinase 2 209 2.4E-73 T 23-10-2018 IPR006259 Adenylate kinase subfamily GO:0004017|GO:0005524|GO:0016776 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 TON_1950 4106e2b9e310b270ce49c693d2c67219 276 Pfam PF01040 UbiA prenyltransferase family 22 256 2.8E-45 T 23-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 TON_1950 4106e2b9e310b270ce49c693d2c67219 276 Gene3D G3DSA:1.10.357.140 9 156 1.7E-17 T 23-10-2018 TON_1950 4106e2b9e310b270ce49c693d2c67219 276 Hamap MF_01286 Digeranylgeranylglyceryl phosphate synthase. 3 275 22.515 T 23-10-2018 IPR023547 Digeranylgeranylglyceryl phosphate synthase GO:0000287|GO:0005886|GO:0008654|GO:0047295 KEGG: 00564+2.5.1.42|MetaCyc: PWY-6349 TON_1876 059161cef1af4b1c648326f73acf528d 640 Gene3D G3DSA:3.40.50.300 7 212 4.7E-65 T 23-10-2018 TON_1876 059161cef1af4b1c648326f73acf528d 640 SUPERFAMILY SSF53300 475 612 1.75E-16 T 23-10-2018 IPR036465 von Willebrand factor A-like domain superfamily TON_1876 059161cef1af4b1c648326f73acf528d 640 SMART SM00327 471 639 2.4E-9 T 23-10-2018 IPR002035 von Willebrand factor, type A TON_1876 059161cef1af4b1c648326f73acf528d 640 Gene3D G3DSA:3.40.50.410 474 625 5.1E-15 T 23-10-2018 IPR036465 von Willebrand factor A-like domain superfamily TON_1876 059161cef1af4b1c648326f73acf528d 640 SUPERFAMILY SSF52540 10 328 1.45E-64 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_1876 059161cef1af4b1c648326f73acf528d 640 Gene3D G3DSA:1.10.8.80 257 337 4.1E-23 T 23-10-2018 TON_1876 059161cef1af4b1c648326f73acf528d 640 Pfam PF00493 MCM2/3/5 family 117 318 1.1E-8 T 23-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 TON_1876 059161cef1af4b1c648326f73acf528d 640 Pfam PF13519 von Willebrand factor type A domain 475 581 2.4E-13 T 23-10-2018 IPR002035 von Willebrand factor, type A TON_1876 059161cef1af4b1c648326f73acf528d 640 SMART SM00382 33 469 9.6E-7 T 23-10-2018 IPR003593 AAA+ ATPase domain TON_0953 efe5a24252709eec26339fd7abe52ce2 70 Pfam PF01200 Ribosomal protein S28e 4 66 1.8E-29 T 23-10-2018 IPR000289 Ribosomal protein S28e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0953 efe5a24252709eec26339fd7abe52ce2 70 ProSitePatterns PS00961 Ribosomal protein S28e signature. 58 66 - T 23-10-2018 IPR028626 Ribosomal protein S28e conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0953 efe5a24252709eec26339fd7abe52ce2 70 Gene3D G3DSA:2.40.50.140 1 70 1.8E-32 T 23-10-2018 TON_0953 efe5a24252709eec26339fd7abe52ce2 70 ProDom PD005541 RIBOSOMAL RIBONUCLEOPROTEIN 40S S28 S28E 30S ACETYLATION S33 S33 CG15527 1 48 2.0E-8 T 23-10-2018 IPR000289 Ribosomal protein S28e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0953 efe5a24252709eec26339fd7abe52ce2 70 SUPERFAMILY SSF50249 3 69 1.48E-25 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold TON_0953 efe5a24252709eec26339fd7abe52ce2 70 Hamap MF_00292 30S ribosomal protein S28e [rps28e]. 1 67 25.309 T 23-10-2018 IPR000289 Ribosomal protein S28e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0981 f50a6a2c002162ad42bd4c7b95931609 375 Gene3D G3DSA:1.10.240.10 227 375 3.8E-56 T 23-10-2018 TON_0981 f50a6a2c002162ad42bd4c7b95931609 375 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 6 360 2.4E-34 T 23-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 TON_0981 f50a6a2c002162ad42bd4c7b95931609 375 Hamap MF_02009 Tyrosine--tRNA ligase [tyrS]. 5 359 47.93 T 23-10-2018 IPR023678 Tyrosine-tRNA ligase, type 4 GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 TON_0981 f50a6a2c002162ad42bd4c7b95931609 375 SUPERFAMILY SSF52374 3 363 7.97E-65 T 23-10-2018 TON_0981 f50a6a2c002162ad42bd4c7b95931609 375 Pfam PF00579 tRNA synthetases class I (W and Y) 33 352 1.1E-43 T 23-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 TON_0981 f50a6a2c002162ad42bd4c7b95931609 375 Gene3D G3DSA:3.40.50.620 1 226 8.3E-59 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TON_0981 f50a6a2c002162ad42bd4c7b95931609 375 PIRSF PIRSF006588 1 375 3.2E-129 T 23-10-2018 IPR023617 Tyrosine-tRNA ligase, archaeal/eukaryotic-type GO:0004831 KEGG: 00970+6.1.1.1 TON_0034 d9734669fc395c99e00291206857313f 211 Gene3D G3DSA:2.60.120.1040 63 188 2.2E-21 T 23-10-2018 TON_0034 d9734669fc395c99e00291206857313f 211 Gene3D G3DSA:2.20.25.420 3 59 1.8E-7 T 23-10-2018 TON_0034 d9734669fc395c99e00291206857313f 211 SMART SM00709 14 174 8.8E-75 T 23-10-2018 IPR004457 Zinc finger, ZPR1-type GO:0008270 TON_0034 d9734669fc395c99e00291206857313f 211 TIGRFAM TIGR00340 zpr1_rel: zinc finger protein ZPR1 homolog 16 181 2.7E-69 T 23-10-2018 IPR004470 Zinc finger, ZPR1-type, subgroup GO:0008270 TON_0034 d9734669fc395c99e00291206857313f 211 Pfam PF03367 ZPR1 zinc-finger domain 15 171 3.0E-38 T 23-10-2018 IPR004457 Zinc finger, ZPR1-type GO:0008270 TON_0034 d9734669fc395c99e00291206857313f 211 TIGRFAM TIGR00310 ZPR1_znf: ZPR1 zinc finger domain 15 204 1.8E-61 T 23-10-2018 IPR004457 Zinc finger, ZPR1-type GO:0008270 TON_1582 a8bfceaf5a6af05de6257e5471d8f9cf 168 PIRSF PIRSF019239 1 166 7.8E-39 T 23-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 TON_1582 a8bfceaf5a6af05de6257e5471d8f9cf 168 Pfam PF01899 Na+/H+ ion antiporter subunit 7 165 1.2E-39 T 23-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 TON_0899 4bd9cedce7bb635b5a638479a7c9c4f6 214 Pfam PF01411 tRNA synthetases class II (A) 13 87 9.9E-13 T 23-10-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 TON_0899 4bd9cedce7bb635b5a638479a7c9c4f6 214 Gene3D G3DSA:2.40.30.130 13 84 1.4E-30 T 23-10-2018 TON_0899 4bd9cedce7bb635b5a638479a7c9c4f6 214 SMART SM00863 166 209 2.2E-8 T 23-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 TON_0899 4bd9cedce7bb635b5a638479a7c9c4f6 214 SUPERFAMILY SSF50447 1 84 1.45E-21 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily TON_0899 4bd9cedce7bb635b5a638479a7c9c4f6 214 Gene3D G3DSA:3.30.980.10 85 213 2.1E-45 T 23-10-2018 TON_0899 4bd9cedce7bb635b5a638479a7c9c4f6 214 SUPERFAMILY SSF55186 85 211 7.59E-34 T 23-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 TON_0899 4bd9cedce7bb635b5a638479a7c9c4f6 214 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 171 209 9.9E-9 T 23-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 TON_1848 71ffd49833f15cddd0e6b7a9ce6ef7ea 185 TIGRFAM TIGR01221 rmlC: dTDP-4-dehydrorhamnose 3,5-epimerase 5 178 2.6E-88 T 23-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 TON_1848 71ffd49833f15cddd0e6b7a9ce6ef7ea 185 Gene3D G3DSA:2.60.120.10 5 184 1.8E-78 T 23-10-2018 IPR014710 RmlC-like jelly roll fold TON_1848 71ffd49833f15cddd0e6b7a9ce6ef7ea 185 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 3 177 1.0E-76 T 23-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 TON_1848 71ffd49833f15cddd0e6b7a9ce6ef7ea 185 SUPERFAMILY SSF51182 3 181 1.07E-80 T 23-10-2018 IPR011051 RmlC-like cupin domain superfamily TON_1848 71ffd49833f15cddd0e6b7a9ce6ef7ea 185 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 8 177 5.3E-78 T 23-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 TON_0385 4b48926cd17453d11f10c74adb949432 333 Pfam PF01594 AI-2E family transporter 10 322 1.1E-39 T 23-10-2018 IPR002549 Transmembrane protein TqsA-like TON_0411 6ebc041697a7b18fcaab35d42dca84f9 581 SMART SM00729 200 447 3.9E-32 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TON_0411 6ebc041697a7b18fcaab35d42dca84f9 581 SUPERFAMILY SSF47781 524 573 1.29E-6 T 23-10-2018 IPR010994 RuvA domain 2-like TON_0411 6ebc041697a7b18fcaab35d42dca84f9 581 Pfam PF04055 Radical SAM superfamily 204 403 2.5E-26 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TON_0411 6ebc041697a7b18fcaab35d42dca84f9 581 SUPERFAMILY SSF102114 179 446 1.08E-27 T 23-10-2018 TON_0411 6ebc041697a7b18fcaab35d42dca84f9 581 Gene3D G3DSA:3.80.30.20 200 457 4.5E-25 T 23-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe TON_0775 859b413cd53a188790516fc8cf8a57b3 954 Pfam PF02516 Oligosaccharyl transferase STT3 subunit 103 525 1.6E-7 T 23-10-2018 IPR003674 Oligosaccharyl transferase, STT3 subunit GO:0004576|GO:0006486|GO:0016020 TON_0775 859b413cd53a188790516fc8cf8a57b3 954 Gene3D G3DSA:2.40.128.390 603 670 8.6E-93 T 23-10-2018 TON_0775 859b413cd53a188790516fc8cf8a57b3 954 Gene3D G3DSA:2.60.40.3020 713 953 1.2E-120 T 23-10-2018 TON_0775 859b413cd53a188790516fc8cf8a57b3 954 Gene3D G3DSA:2.60.40.3030 813 945 1.2E-120 T 23-10-2018 TON_0775 859b413cd53a188790516fc8cf8a57b3 954 Gene3D G3DSA:3.40.50.12610 497 711 8.6E-93 T 23-10-2018 TON_0066 706eafb35ee985507041f4c7094a33dc 347 ProSitePatterns PS00474 Ribosomal protein L3 signature. 193 216 - T 23-10-2018 IPR019926 Ribosomal protein L3, conserved site TON_0066 706eafb35ee985507041f4c7094a33dc 347 Gene3D G3DSA:3.30.1430.10 77 188 1.3E-122 T 23-10-2018 TON_0066 706eafb35ee985507041f4c7094a33dc 347 TIGRFAM TIGR03626 L3_arch: ribosomal protein uL3 5 346 3.8E-136 T 23-10-2018 IPR019928 Ribosomal protein L3, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 TON_0066 706eafb35ee985507041f4c7094a33dc 347 Pfam PF00297 Ribosomal protein L3 3 347 6.1E-90 T 23-10-2018 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TON_0066 706eafb35ee985507041f4c7094a33dc 347 Gene3D G3DSA:4.10.960.10 6 257 1.3E-122 T 23-10-2018 TON_0066 706eafb35ee985507041f4c7094a33dc 347 SUPERFAMILY SSF50447 3 347 3.09E-96 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily TON_0066 706eafb35ee985507041f4c7094a33dc 347 Gene3D G3DSA:2.40.30.10 39 327 1.3E-122 T 23-10-2018 TON_0066 706eafb35ee985507041f4c7094a33dc 347 Hamap MF_01325_A 50S ribosomal protein L3 [rplC]. 1 347 49.668 T 23-10-2018 IPR019928 Ribosomal protein L3, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 TON_1414 52ff801a77210eab9ac8a09b6dd9fca1 326 Gene3D G3DSA:3.40.50.300 2 169 3.9E-63 T 23-10-2018 TON_1414 52ff801a77210eab9ac8a09b6dd9fca1 326 Pfam PF08542 Replication factor C C-terminal domain 235 320 8.1E-23 T 23-10-2018 IPR013748 Replication factor C, C-terminal Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-176187|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804756|Reactome: R-HSA-69091|Reactome: R-HSA-69473 TON_1414 52ff801a77210eab9ac8a09b6dd9fca1 326 Gene3D G3DSA:1.10.8.60 170 233 4.7E-27 T 23-10-2018 TON_1414 52ff801a77210eab9ac8a09b6dd9fca1 326 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 49 167 2.2E-18 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TON_1414 52ff801a77210eab9ac8a09b6dd9fca1 326 SMART SM00382 45 176 4.5E-15 T 23-10-2018 IPR003593 AAA+ ATPase domain TON_1414 52ff801a77210eab9ac8a09b6dd9fca1 326 SUPERFAMILY SSF52540 12 227 5.75E-60 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_1414 52ff801a77210eab9ac8a09b6dd9fca1 326 SUPERFAMILY SSF48019 235 324 2.93E-24 T 23-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 TON_1414 52ff801a77210eab9ac8a09b6dd9fca1 326 Hamap MF_01509 Replication factor C small subunit [rfcS]. 11 325 51.526 T 23-10-2018 IPR023748 Replication factor C small subunit, archaeal GO:0003689|GO:0005524|GO:0005663|GO:0006260 TON_1414 52ff801a77210eab9ac8a09b6dd9fca1 326 Gene3D G3DSA:1.20.272.10 234 326 2.0E-37 T 23-10-2018 TON_0506 932ef3dc93971cbb1229db46fb62a8c5 293 SMART SM01130 1 292 1.3E-95 T 23-10-2018 IPR002220 DapA-like GO:0016829 TON_0506 932ef3dc93971cbb1229db46fb62a8c5 293 PIRSF PIRSF001365 1 292 8.1E-81 T 23-10-2018 IPR002220 DapA-like GO:0016829 TON_0506 932ef3dc93971cbb1229db46fb62a8c5 293 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 131 161 - T 23-10-2018 IPR020625 Schiff base-forming aldolase, active site GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 TON_0506 932ef3dc93971cbb1229db46fb62a8c5 293 Gene3D G3DSA:3.20.20.70 1 292 1.6E-89 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TON_0506 932ef3dc93971cbb1229db46fb62a8c5 293 SUPERFAMILY SSF51569 2 291 1.99E-79 T 23-10-2018 TON_0506 932ef3dc93971cbb1229db46fb62a8c5 293 Pfam PF00701 Dihydrodipicolinate synthetase family 2 289 8.7E-63 T 23-10-2018 IPR002220 DapA-like GO:0016829 TON_0506 932ef3dc93971cbb1229db46fb62a8c5 293 PRINTS PR00146 Dihydrodipicolinate synthase signature 69 87 2.2E-15 T 23-10-2018 IPR002220 DapA-like GO:0016829 TON_0506 932ef3dc93971cbb1229db46fb62a8c5 293 PRINTS PR00146 Dihydrodipicolinate synthase signature 34 55 2.2E-15 T 23-10-2018 IPR002220 DapA-like GO:0016829 TON_0506 932ef3dc93971cbb1229db46fb62a8c5 293 PRINTS PR00146 Dihydrodipicolinate synthase signature 126 143 2.2E-15 T 23-10-2018 IPR002220 DapA-like GO:0016829 TON_0506 932ef3dc93971cbb1229db46fb62a8c5 293 PRINTS PR00146 Dihydrodipicolinate synthase signature 101 117 2.2E-15 T 23-10-2018 IPR002220 DapA-like GO:0016829 TON_0687 94ceee8fe2f53b35ea16be4891f98c04 484 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 250 432 4.7E-50 T 23-10-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 TON_0687 94ceee8fe2f53b35ea16be4891f98c04 484 SUPERFAMILY SSF52540 1 231 9.42E-47 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_0687 94ceee8fe2f53b35ea16be4891f98c04 484 TIGRFAM TIGR00313 cobQ: cobyric acid synthase CobQ 5 476 5.2E-156 T 23-10-2018 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 TON_0687 94ceee8fe2f53b35ea16be4891f98c04 484 Hamap MF_00028 Cobyric acid synthase [cobQ]. 1 484 160.847 T 23-10-2018 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 TON_0687 94ceee8fe2f53b35ea16be4891f98c04 484 Gene3D G3DSA:3.40.50.880 248 391 7.9E-16 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like TON_0687 94ceee8fe2f53b35ea16be4891f98c04 484 SUPERFAMILY SSF52317 193 366 1.02E-27 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like TON_0687 94ceee8fe2f53b35ea16be4891f98c04 484 Gene3D G3DSA:3.40.50.300 1 241 3.3E-47 T 23-10-2018 TON_0687 94ceee8fe2f53b35ea16be4891f98c04 484 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 5 226 4.2E-19 T 23-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain TON_1501 1c34b0df531bc8d0708a8bae21fb23a7 420 Gene3D G3DSA:3.50.50.60 4 403 1.4E-137 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TON_1501 1c34b0df531bc8d0708a8bae21fb23a7 420 PRINTS PR00419 Adrenodoxin reductase family signature 25 38 4.5E-5 T 23-10-2018 TON_1501 1c34b0df531bc8d0708a8bae21fb23a7 420 PRINTS PR00419 Adrenodoxin reductase family signature 2 24 4.5E-5 T 23-10-2018 TON_1501 1c34b0df531bc8d0708a8bae21fb23a7 420 Pfam PF13450 NAD(P)-binding Rossmann-like domain 5 69 6.1E-14 T 23-10-2018 TON_1501 1c34b0df531bc8d0708a8bae21fb23a7 420 SUPERFAMILY SSF51905 1 386 1.06E-37 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TON_1501 1c34b0df531bc8d0708a8bae21fb23a7 420 Gene3D G3DSA:3.90.660.50 83 359 1.4E-137 T 23-10-2018 TON_0516 947cf7943ca0dfffdabc04f918c7a1da 181 SUPERFAMILY SSF74853 59 170 3.4E-21 T 23-10-2018 IPR036415 Lamin tail domain superfamily TON_0516 947cf7943ca0dfffdabc04f918c7a1da 181 Pfam PF00932 Lamin Tail Domain 58 171 1.7E-27 T 23-10-2018 IPR001322 Lamin tail domain TON_0516 947cf7943ca0dfffdabc04f918c7a1da 181 Gene3D G3DSA:2.60.40.1260 77 169 2.0E-10 T 23-10-2018 IPR036415 Lamin tail domain superfamily TON_1757 e83a9b07b1c7593421e8ccba0efcf9ca 404 Pfam PF01411 tRNA synthetases class II (A) 18 94 3.6E-11 T 23-10-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 TON_1757 e83a9b07b1c7593421e8ccba0efcf9ca 404 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 188 231 1.2E-13 T 23-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 TON_1757 e83a9b07b1c7593421e8ccba0efcf9ca 404 SUPERFAMILY SSF55186 92 235 1.96E-35 T 23-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 TON_1757 e83a9b07b1c7593421e8ccba0efcf9ca 404 Pfam PF02272 DHHA1 domain 268 399 5.4E-15 T 23-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 TON_1757 e83a9b07b1c7593421e8ccba0efcf9ca 404 Gene3D G3DSA:3.30.980.10 92 245 6.1E-43 T 23-10-2018 TON_1757 e83a9b07b1c7593421e8ccba0efcf9ca 404 Gene3D G3DSA:2.40.30.130 1 91 1.3E-18 T 23-10-2018 TON_1757 e83a9b07b1c7593421e8ccba0efcf9ca 404 SUPERFAMILY SSF50447 1 90 4.94E-14 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily TON_1757 e83a9b07b1c7593421e8ccba0efcf9ca 404 SMART SM00863 188 231 2.0E-16 T 23-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 TON_1757 e83a9b07b1c7593421e8ccba0efcf9ca 404 Gene3D G3DSA:3.10.310.40 299 402 2.2E-9 T 23-10-2018 TON_0505 15cbb21cb12bff7ea865e40c9cda241c 642 SUPERFAMILY SSF55190 8 116 2.22E-19 T 23-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 TON_0505 15cbb21cb12bff7ea865e40c9cda241c 642 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 14 365 2.2E-79 T 23-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 TON_0505 15cbb21cb12bff7ea865e40c9cda241c 642 SMART SM01016 8 95 2.4E-21 T 23-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 TON_0505 15cbb21cb12bff7ea865e40c9cda241c 642 Gene3D G3DSA:3.40.50.620 122 523 1.4E-158 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TON_0505 15cbb21cb12bff7ea865e40c9cda241c 642 Pfam PF05746 DALR anticodon binding domain 520 642 1.3E-35 T 23-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 TON_0505 15cbb21cb12bff7ea865e40c9cda241c 642 Hamap MF_00123 Arginine--tRNA ligase [argS]. 12 642 27.977 T 23-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 TON_0505 15cbb21cb12bff7ea865e40c9cda241c 642 Gene3D G3DSA:1.10.730.10 524 642 2.1E-41 T 23-10-2018 TON_0505 15cbb21cb12bff7ea865e40c9cda241c 642 Gene3D G3DSA:3.30.1360.70 5 121 2.9E-32 T 23-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 TON_0505 15cbb21cb12bff7ea865e40c9cda241c 642 SUPERFAMILY SSF47323 516 642 2.35E-34 T 23-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 TON_0505 15cbb21cb12bff7ea865e40c9cda241c 642 PRINTS PR01038 Arginyl-tRNA synthetase signature 330 351 1.7E-23 T 23-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 TON_0505 15cbb21cb12bff7ea865e40c9cda241c 642 PRINTS PR01038 Arginyl-tRNA synthetase signature 125 140 1.7E-23 T 23-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 TON_0505 15cbb21cb12bff7ea865e40c9cda241c 642 PRINTS PR01038 Arginyl-tRNA synthetase signature 164 177 1.7E-23 T 23-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 TON_0505 15cbb21cb12bff7ea865e40c9cda241c 642 PRINTS PR01038 Arginyl-tRNA synthetase signature 140 156 1.7E-23 T 23-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 TON_0505 15cbb21cb12bff7ea865e40c9cda241c 642 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 14 95 1.9E-14 T 23-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 TON_0505 15cbb21cb12bff7ea865e40c9cda241c 642 SMART SM00836 520 642 1.2E-49 T 23-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 TON_0505 15cbb21cb12bff7ea865e40c9cda241c 642 Pfam PF00750 tRNA synthetases class I (R) 105 355 1.8E-25 T 23-10-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 TON_0505 15cbb21cb12bff7ea865e40c9cda241c 642 Pfam PF00750 tRNA synthetases class I (R) 388 492 1.4E-12 T 23-10-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 TON_0505 15cbb21cb12bff7ea865e40c9cda241c 642 SUPERFAMILY SSF52374 121 513 2.04E-79 T 23-10-2018 TON_0505 15cbb21cb12bff7ea865e40c9cda241c 642 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 135 144 - T 23-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 TON_1082 ac0a91504f3b1bb698700b93048dfbe1 247 Gene3D G3DSA:3.40.50.300 1 243 8.8E-58 T 23-10-2018 TON_1082 ac0a91504f3b1bb698700b93048dfbe1 247 Pfam PF03029 Conserved hypothetical ATP binding protein 6 241 1.3E-50 T 23-10-2018 IPR004130 GPN-loop GTPase TON_1082 ac0a91504f3b1bb698700b93048dfbe1 247 SUPERFAMILY SSF52540 2 239 1.33E-37 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_0247 312221f61c468b0b3ba31d6e44dec992 189 Pfam PF06560 Glucose-6-phosphate isomerase (GPI) 25 181 8.2E-42 T 23-10-2018 IPR010551 Glucose-6-phosphate isomerase, prokaryote GO:0004347|GO:0005737|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385 TON_0247 312221f61c468b0b3ba31d6e44dec992 189 Gene3D G3DSA:2.60.120.10 1 189 1.8E-74 T 23-10-2018 IPR014710 RmlC-like jelly roll fold TON_0247 312221f61c468b0b3ba31d6e44dec992 189 PIRSF PIRSF019325 1 189 1.9E-75 T 23-10-2018 IPR016758 Glucose-6-phosphate isomerase, archaea/bacteria GO:0004347|GO:0005506 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385 TON_0247 312221f61c468b0b3ba31d6e44dec992 189 Hamap MF_01410 Glucose-6-phosphate isomerase [pgiA]. 2 185 45.83 T 23-10-2018 IPR016758 Glucose-6-phosphate isomerase, archaea/bacteria GO:0004347|GO:0005506 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385 TON_0247 312221f61c468b0b3ba31d6e44dec992 189 SUPERFAMILY SSF51182 2 187 6.03E-44 T 23-10-2018 IPR011051 RmlC-like cupin domain superfamily TON_0181 f8cc2978ab22f0b12ba60c826fd2943f 339 Gene3D G3DSA:3.30.70.1730 15 211 3.8E-74 T 23-10-2018 TON_0181 f8cc2978ab22f0b12ba60c826fd2943f 339 Gene3D G3DSA:3.90.105.20 107 186 3.8E-74 T 23-10-2018 TON_0181 f8cc2978ab22f0b12ba60c826fd2943f 339 Pfam PF00466 Ribosomal protein L10 5 105 1.1E-21 T 23-10-2018 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 TON_0181 f8cc2978ab22f0b12ba60c826fd2943f 339 Hamap MF_00280 50S ribosomal protein L10 [rpl10]. 1 283 35.965 T 23-10-2018 IPR022909 50S ribosomal protein L10, archaea TON_0181 f8cc2978ab22f0b12ba60c826fd2943f 339 SUPERFAMILY SSF160369 5 141 3.4E-23 T 23-10-2018 TON_0089 6b3d52396c39bd89abfc5bb01b2da0cc 481 Pfam PF00344 SecY translocase 72 460 6.2E-70 T 23-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TON_0089 6b3d52396c39bd89abfc5bb01b2da0cc 481 Gene3D G3DSA:1.10.3370.10 26 481 3.7E-179 T 23-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TON_0089 6b3d52396c39bd89abfc5bb01b2da0cc 481 PRINTS PR00303 Preprotein translocase SecY subunit signature 185 208 1.4E-8 T 23-10-2018 TON_0089 6b3d52396c39bd89abfc5bb01b2da0cc 481 PRINTS PR00303 Preprotein translocase SecY subunit signature 30 48 1.4E-8 T 23-10-2018 TON_0089 6b3d52396c39bd89abfc5bb01b2da0cc 481 PRINTS PR00303 Preprotein translocase SecY subunit signature 445 463 1.4E-8 T 23-10-2018 TON_0089 6b3d52396c39bd89abfc5bb01b2da0cc 481 PRINTS PR00303 Preprotein translocase SecY subunit signature 159 184 1.4E-8 T 23-10-2018 TON_0089 6b3d52396c39bd89abfc5bb01b2da0cc 481 ProSitePatterns PS00755 Protein secY signature 1. 72 91 - T 23-10-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TON_0089 6b3d52396c39bd89abfc5bb01b2da0cc 481 ProSitePatterns PS00756 Protein secY signature 2. 178 195 - T 23-10-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TON_0089 6b3d52396c39bd89abfc5bb01b2da0cc 481 PIRSF PIRSF004557 5 481 1.7E-102 T 23-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TON_0089 6b3d52396c39bd89abfc5bb01b2da0cc 481 SUPERFAMILY SSF103491 9 467 1.57E-109 T 23-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TON_0089 6b3d52396c39bd89abfc5bb01b2da0cc 481 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 27 469 1.4E-92 T 23-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TON_0089 6b3d52396c39bd89abfc5bb01b2da0cc 481 Hamap MF_01465 Protein translocase subunit SecY [secY]. 17 476 20.243 T 23-10-2018 IPR026593 Protein translocase subunit SecY TON_0089 6b3d52396c39bd89abfc5bb01b2da0cc 481 Pfam PF10559 Plug domain of Sec61p 38 71 2.0E-11 T 23-10-2018 IPR019561 Translocon Sec61/SecY, plug domain Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TON_0657 08fd16accdd67e96064c05cbe1bdc892 658 Pfam PF02421 Ferrous iron transport protein B 4 159 5.7E-64 T 23-10-2018 IPR030389 FeoB-type guanine nucleotide-binding (G) domain GO:0005525 TON_0657 08fd16accdd67e96064c05cbe1bdc892 658 Gene3D G3DSA:3.40.50.300 1 169 7.9E-48 T 23-10-2018 TON_0657 08fd16accdd67e96064c05cbe1bdc892 658 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 26 44 1.1E-6 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 TON_0657 08fd16accdd67e96064c05cbe1bdc892 658 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 1.1E-6 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 TON_0657 08fd16accdd67e96064c05cbe1bdc892 658 Pfam PF07664 Ferrous iron transport protein B C terminus 457 509 4.2E-19 T 23-10-2018 IPR011640 Ferrous iron transport protein B, C-terminal GO:0015093|GO:0015684|GO:0016021 TON_0657 08fd16accdd67e96064c05cbe1bdc892 658 TIGRFAM TIGR00437 feoB: ferrous iron transport protein B 9 625 4.1E-190 T 23-10-2018 IPR003373 Ferrous iron transport protein B GO:0005525|GO:0015093|GO:0015684|GO:0016021 TON_0657 08fd16accdd67e96064c05cbe1bdc892 658 Pfam PF07670 Nucleoside recognition 514 628 7.1E-29 T 23-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 TON_0657 08fd16accdd67e96064c05cbe1bdc892 658 Pfam PF07670 Nucleoside recognition 353 447 6.6E-13 T 23-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 TON_0657 08fd16accdd67e96064c05cbe1bdc892 658 SUPERFAMILY SSF52540 5 174 3.36E-42 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_1809 9c5f7b2f144d18c1bda7975f81d4eb1f 143 Pfam PF02566 OsmC-like protein 37 138 6.7E-22 T 23-10-2018 IPR003718 OsmC/Ohr family TON_1809 9c5f7b2f144d18c1bda7975f81d4eb1f 143 SUPERFAMILY SSF82784 7 141 4.19E-30 T 23-10-2018 IPR036102 OsmC/Ohr superfamily TON_1809 9c5f7b2f144d18c1bda7975f81d4eb1f 143 Gene3D G3DSA:3.30.300.20 3 142 3.5E-29 T 23-10-2018 IPR015946 K homology domain-like, alpha/beta TON_1312 903664e37549b519cd98e23d2d98710c 648 Pfam PF00037 4Fe-4S binding domain 619 640 9.0E-7 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TON_1312 903664e37549b519cd98e23d2d98710c 648 Gene3D G3DSA:3.30.70.20 586 642 3.6E-10 T 23-10-2018 TON_1312 903664e37549b519cd98e23d2d98710c 648 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 410 564 4.7E-30 T 23-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 TON_1312 903664e37549b519cd98e23d2d98710c 648 Gene3D G3DSA:3.40.50.970 7 196 5.0E-53 T 23-10-2018 TON_1312 903664e37549b519cd98e23d2d98710c 648 Gene3D G3DSA:3.40.50.970 389 570 1.1E-22 T 23-10-2018 TON_1312 903664e37549b519cd98e23d2d98710c 648 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 625 636 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TON_1312 903664e37549b519cd98e23d2d98710c 648 SUPERFAMILY SSF52518 380 602 2.47E-30 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold TON_1312 903664e37549b519cd98e23d2d98710c 648 SUPERFAMILY SSF52518 14 250 3.16E-56 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold TON_1312 903664e37549b519cd98e23d2d98710c 648 PIRSF PIRSF006439 5 647 1.2E-261 T 23-10-2018 IPR017721 Indolepyruvate ferredoxin oxidoreductase, alpha subunit GO:0043805|GO:0055114 TON_1312 903664e37549b519cd98e23d2d98710c 648 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 28 207 1.6E-15 T 23-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 TON_1312 903664e37549b519cd98e23d2d98710c 648 TIGRFAM TIGR03336 IOR_alpha: indolepyruvate ferredoxin oxidoreductase, alpha subunit 16 640 2.0E-271 T 23-10-2018 IPR017721 Indolepyruvate ferredoxin oxidoreductase, alpha subunit GO:0043805|GO:0055114 TON_1312 903664e37549b519cd98e23d2d98710c 648 SUPERFAMILY SSF54862 583 640 4.95E-14 T 23-10-2018 TON_1312 903664e37549b519cd98e23d2d98710c 648 SUPERFAMILY SSF52922 248 355 1.64E-7 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TON_0933 4c14d93892666d261ec4413c341a1bf8 172 Pfam PF03266 NTPase 2 161 8.0E-56 T 23-10-2018 IPR004948 Nucleoside-triphosphatase, THEP1 type GO:0098519 KEGG: 00230+3.6.1.15|KEGG: 00730+3.6.1.15|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210 TON_0933 4c14d93892666d261ec4413c341a1bf8 172 Gene3D G3DSA:3.40.50.300 1 169 3.1E-42 T 23-10-2018 TON_0933 4c14d93892666d261ec4413c341a1bf8 172 SMART SM00382 2 152 0.0017 T 23-10-2018 IPR003593 AAA+ ATPase domain TON_0933 4c14d93892666d261ec4413c341a1bf8 172 SUPERFAMILY SSF52540 3 147 6.37E-23 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_0933 4c14d93892666d261ec4413c341a1bf8 172 Hamap MF_00796 Nucleoside-triphosphatase . 1 169 29.277 T 23-10-2018 IPR004948 Nucleoside-triphosphatase, THEP1 type GO:0098519 KEGG: 00230+3.6.1.15|KEGG: 00730+3.6.1.15|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210 TON_1635 07baf754b1f0ebae594c3c6abfa87691 177 Pfam PF01613 Flavin reductase like domain 11 142 2.0E-21 T 23-10-2018 IPR002563 Flavin reductase like domain GO:0010181 TON_1635 07baf754b1f0ebae594c3c6abfa87691 177 SUPERFAMILY SSF50475 4 161 1.32E-37 T 23-10-2018 TON_1635 07baf754b1f0ebae594c3c6abfa87691 177 SMART SM00903 5 149 1.0E-16 T 23-10-2018 IPR002563 Flavin reductase like domain GO:0010181 TON_1635 07baf754b1f0ebae594c3c6abfa87691 177 Gene3D G3DSA:2.30.110.10 1 163 6.4E-45 T 23-10-2018 IPR012349 FMN-binding split barrel GO:0048037 TON_0594 b6d81fd958476ce19baf3223d80d0a7d 407 Gene3D G3DSA:3.40.50.2300 138 329 4.6E-87 T 23-10-2018 TON_0594 b6d81fd958476ce19baf3223d80d0a7d 407 Gene3D G3DSA:3.40.50.2300 36 312 4.6E-87 T 23-10-2018 TON_0594 b6d81fd958476ce19baf3223d80d0a7d 407 Pfam PF02608 ABC transporter substrate-binding protein PnrA-like 37 340 3.6E-53 T 23-10-2018 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 TON_0594 b6d81fd958476ce19baf3223d80d0a7d 407 SUPERFAMILY SSF53822 52 299 1.88E-7 T 23-10-2018 IPR028082 Periplasmic binding protein-like I TON_1869 80389d997a6122642ee99d04ca482f12 341 Pfam PF13424 Tetratricopeptide repeat 133 202 2.0E-8 T 23-10-2018 TON_1869 80389d997a6122642ee99d04ca482f12 341 Pfam PF13424 Tetratricopeptide repeat 58 122 9.7E-8 T 23-10-2018 TON_1869 80389d997a6122642ee99d04ca482f12 341 SUPERFAMILY SSF48452 52 237 2.28E-20 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TON_1869 80389d997a6122642ee99d04ca482f12 341 SMART SM00028 134 167 71.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TON_1869 80389d997a6122642ee99d04ca482f12 341 SMART SM00028 93 126 0.0032 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TON_1869 80389d997a6122642ee99d04ca482f12 341 SMART SM00028 174 207 45.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TON_1869 80389d997a6122642ee99d04ca482f12 341 SMART SM00028 55 88 220.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TON_1869 80389d997a6122642ee99d04ca482f12 341 Gene3D G3DSA:1.25.40.10 52 332 2.1E-24 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TON_0741 5896316d9b7181576155d81c4252fc08 503 Gene3D G3DSA:3.60.21.10 256 491 1.3E-19 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like TON_0741 5896316d9b7181576155d81c4252fc08 503 Gene3D G3DSA:3.60.21.10 1 248 1.8E-39 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like TON_0741 5896316d9b7181576155d81c4252fc08 503 Pfam PF00149 Calcineurin-like phosphoesterase 2 185 8.4E-20 T 23-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 TON_0741 5896316d9b7181576155d81c4252fc08 503 SUPERFAMILY SSF56300 270 484 2.35E-29 T 23-10-2018 TON_0741 5896316d9b7181576155d81c4252fc08 503 SUPERFAMILY SSF56300 2 234 4.36E-51 T 23-10-2018 TON_0741 5896316d9b7181576155d81c4252fc08 503 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 279 472 2.0E-7 T 23-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 TON_0311 a2fbb33e0e2a5e96aad062e1eba14c31 782 SUPERFAMILY SSF56059 3 381 9.89E-108 T 23-10-2018 TON_0311 a2fbb33e0e2a5e96aad062e1eba14c31 782 Gene3D G3DSA:3.30.1490.20 3 197 1.2E-73 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 TON_0311 a2fbb33e0e2a5e96aad062e1eba14c31 782 SUPERFAMILY SSF51621 481 776 5.76E-94 T 23-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 TON_0311 a2fbb33e0e2a5e96aad062e1eba14c31 782 SUPERFAMILY SSF52009 353 461 1.96E-36 T 23-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 TON_0311 a2fbb33e0e2a5e96aad062e1eba14c31 782 TIGRFAM TIGR01418 PEP_synth: phosphoenolpyruvate synthase 7 769 1.3E-291 T 23-10-2018 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484|MetaCyc: PWY-6142 TON_0311 a2fbb33e0e2a5e96aad062e1eba14c31 782 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 412 423 - T 23-10-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 TON_0311 a2fbb33e0e2a5e96aad062e1eba14c31 782 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 674 692 - T 23-10-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 TON_0311 a2fbb33e0e2a5e96aad062e1eba14c31 782 Pfam PF00391 PEP-utilising enzyme, mobile domain 381 453 2.7E-27 T 23-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 TON_0311 a2fbb33e0e2a5e96aad062e1eba14c31 782 Gene3D G3DSA:3.20.20.60 461 781 8.3E-104 T 23-10-2018 TON_0311 a2fbb33e0e2a5e96aad062e1eba14c31 782 PIRSF PIRSF000854 1 536 8.0E-153 T 23-10-2018 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484|MetaCyc: PWY-6142 TON_0311 a2fbb33e0e2a5e96aad062e1eba14c31 782 PIRSF PIRSF000854 529 773 1.4E-55 T 23-10-2018 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484|MetaCyc: PWY-6142 TON_0311 a2fbb33e0e2a5e96aad062e1eba14c31 782 Gene3D G3DSA:3.30.470.20 198 354 7.5E-54 T 23-10-2018 TON_0311 a2fbb33e0e2a5e96aad062e1eba14c31 782 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 674 689 1.6E-12 T 23-10-2018 TON_0311 a2fbb33e0e2a5e96aad062e1eba14c31 782 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 727 739 1.6E-12 T 23-10-2018 TON_0311 a2fbb33e0e2a5e96aad062e1eba14c31 782 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 691 706 1.6E-12 T 23-10-2018 TON_0311 a2fbb33e0e2a5e96aad062e1eba14c31 782 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 510 529 1.6E-12 T 23-10-2018 TON_0311 a2fbb33e0e2a5e96aad062e1eba14c31 782 Gene3D G3DSA:3.50.30.10 355 460 2.7E-44 T 23-10-2018 TON_0311 a2fbb33e0e2a5e96aad062e1eba14c31 782 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 480 767 6.2E-94 T 23-10-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 TON_0311 a2fbb33e0e2a5e96aad062e1eba14c31 782 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 19 351 2.6E-120 T 23-10-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 TON_1073 33bb16849dfc3c3e56bdba6e02f07585 127 Pfam PF05763 Protein of unknown function (DUF835) 10 124 5.2E-21 T 23-10-2018 IPR008553 Domain of unknown function DUF835 TON_0392 0f12c793f6cdfc53afe2e6fb0237d168 421 SUPERFAMILY SSF50475 5 279 2.59E-67 T 23-10-2018 TON_0392 0f12c793f6cdfc53afe2e6fb0237d168 421 SUPERFAMILY SSF143968 282 419 1.44E-41 T 23-10-2018 TON_0392 0f12c793f6cdfc53afe2e6fb0237d168 421 TIGRFAM TIGR00148 TIGR00148: decarboxylase, UbiD family 3 409 3.9E-118 T 23-10-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 TON_0392 0f12c793f6cdfc53afe2e6fb0237d168 421 Gene3D G3DSA:3.40.1670.10 296 408 6.5E-38 T 23-10-2018 TON_0392 0f12c793f6cdfc53afe2e6fb0237d168 421 Pfam PF01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 7 385 4.7E-103 T 23-10-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 TON_0166 690d9f5b91a569ac3c98375f45207dbc 444 SMART SM00418 366 444 4.5E-12 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TON_0166 690d9f5b91a569ac3c98375f45207dbc 444 Gene3D G3DSA:1.10.10.10 370 443 9.2E-15 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TON_0166 690d9f5b91a569ac3c98375f45207dbc 444 Gene3D G3DSA:3.40.50.1100 96 192 7.8E-97 T 23-10-2018 TON_0166 690d9f5b91a569ac3c98375f45207dbc 444 SUPERFAMILY SSF46785 373 441 2.22E-16 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TON_0166 690d9f5b91a569ac3c98375f45207dbc 444 Pfam PF03551 Transcriptional regulator PadR-like family 377 440 4.2E-10 T 23-10-2018 IPR005149 Transcription regulator PadR, N-terminal TON_0166 690d9f5b91a569ac3c98375f45207dbc 444 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 61 353 3.2E-60 T 23-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme TON_0166 690d9f5b91a569ac3c98375f45207dbc 444 Gene3D G3DSA:3.40.50.1100 49 358 7.8E-97 T 23-10-2018 TON_0166 690d9f5b91a569ac3c98375f45207dbc 444 SUPERFAMILY SSF53686 14 358 9.17E-74 T 23-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme TON_1622 5205427b8f99418a01f8258f9937edd8 232 SUPERFAMILY SSF69572 2 230 2.75E-77 T 23-10-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 TON_1622 5205427b8f99418a01f8258f9937edd8 232 Pfam PF00899 ThiF family 10 231 1.8E-55 T 23-10-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 TON_1622 5205427b8f99418a01f8258f9937edd8 232 Gene3D G3DSA:3.40.50.720 2 232 3.9E-71 T 23-10-2018 TON_0081 00cbd419b9b1483f63fe0272083e1ff4 130 Gene3D G3DSA:3.30.1490.10 70 128 1.5E-27 T 23-10-2018 TON_0081 00cbd419b9b1483f63fe0272083e1ff4 130 SUPERFAMILY SSF56047 3 130 4.58E-40 T 23-10-2018 IPR035987 Ribosomal protein S8 superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0081 00cbd419b9b1483f63fe0272083e1ff4 130 ProSitePatterns PS00053 Ribosomal protein S8 signature. 100 117 - T 23-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0081 00cbd419b9b1483f63fe0272083e1ff4 130 Gene3D G3DSA:3.30.1370.30 1 69 5.9E-33 T 23-10-2018 TON_0081 00cbd419b9b1483f63fe0272083e1ff4 130 Pfam PF00410 Ribosomal protein S8 5 130 1.6E-28 T 23-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0081 00cbd419b9b1483f63fe0272083e1ff4 130 Hamap MF_01302_A 30S ribosomal protein S8 [rpsH]. 2 130 38.553 T 23-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_1369 3355a070dc83696d0f1c9e011650cba4 260 Pfam PF01435 Peptidase family M48 57 244 9.4E-22 T 23-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 TON_1369 3355a070dc83696d0f1c9e011650cba4 260 Gene3D G3DSA:3.30.2010.10 50 132 2.5E-18 T 23-10-2018 TON_1919 c09f78b33cb4ce54bac88a9e2cfb9583 562 Gene3D G3DSA:3.40.630.10 28 404 1.2E-53 T 23-10-2018 TON_1919 c09f78b33cb4ce54bac88a9e2cfb9583 562 SUPERFAMILY SSF53187 9 421 6.77E-30 T 23-10-2018 TON_1919 c09f78b33cb4ce54bac88a9e2cfb9583 562 Pfam PF02225 PA domain 119 189 2.8E-6 T 23-10-2018 IPR003137 PA domain TON_1919 c09f78b33cb4ce54bac88a9e2cfb9583 562 Pfam PF04389 Peptidase family M28 228 412 1.1E-17 T 23-10-2018 IPR007484 Peptidase M28 TON_1919 c09f78b33cb4ce54bac88a9e2cfb9583 562 Gene3D G3DSA:3.50.30.30 73 208 1.2E-53 T 23-10-2018 TON_1598 675c1150cca62d96a0e7c7accef5ba59 232 SUPERFAMILY SSF55469 51 231 2.62E-37 T 23-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 TON_1598 675c1150cca62d96a0e7c7accef5ba59 232 Pfam PF00881 Nitroreductase family 57 229 2.1E-33 T 23-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 TON_1598 675c1150cca62d96a0e7c7accef5ba59 232 Gene3D G3DSA:3.40.109.10 33 231 3.1E-74 T 23-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 TON_1598 675c1150cca62d96a0e7c7accef5ba59 232 TIGRFAM TIGR03605 antibiot_sagB: SagB-type dehydrogenase domain 72 229 5.6E-48 T 23-10-2018 IPR020051 SagB-type dehydrogenase domain TON_0914 c9070b29228a93ae9eea05000864a3ee 147 SUPERFAMILY SSF46579 7 139 2.22E-29 T 23-10-2018 TON_0914 c9070b29228a93ae9eea05000864a3ee 147 Hamap MF_00308 Prefoldin subunit alpha [pfdA]. 3 138 15.828 T 23-10-2018 IPR011599 Prefoldin alpha subunit, archaea-type GO:0006457|GO:0016272|GO:0051082 Reactome: R-HSA-389957 TON_0914 c9070b29228a93ae9eea05000864a3ee 147 Gene3D G3DSA:1.10.287.370 1 146 3.0E-45 T 23-10-2018 IPR009053 Prefoldin TON_0914 c9070b29228a93ae9eea05000864a3ee 147 Pfam PF02996 Prefoldin subunit 18 138 3.7E-28 T 23-10-2018 IPR004127 Prefoldin alpha-like TON_0914 c9070b29228a93ae9eea05000864a3ee 147 TIGRFAM TIGR00293 TIGR00293: prefoldin, alpha subunit 8 138 2.6E-36 T 23-10-2018 IPR011599 Prefoldin alpha subunit, archaea-type GO:0006457|GO:0016272|GO:0051082 Reactome: R-HSA-389957 TON_0592 3bfdee637874ff1789f48bd276cccb61 301 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 25 298 6.3E-109 T 23-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 TON_0592 3bfdee637874ff1789f48bd276cccb61 301 SMART SM00382 103 298 7.5E-8 T 23-10-2018 IPR003593 AAA+ ATPase domain TON_0592 3bfdee637874ff1789f48bd276cccb61 301 Pfam PF00448 SRP54-type protein, GTPase domain 104 298 1.6E-79 T 23-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 TON_0592 3bfdee637874ff1789f48bd276cccb61 301 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 272 285 - T 23-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 TON_0592 3bfdee637874ff1789f48bd276cccb61 301 Gene3D G3DSA:1.20.120.140 2 87 1.6E-21 T 23-10-2018 TON_0592 3bfdee637874ff1789f48bd276cccb61 301 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 24 299 58.258 T 23-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 TON_0592 3bfdee637874ff1789f48bd276cccb61 301 Gene3D G3DSA:3.40.50.300 90 298 7.4E-86 T 23-10-2018 TON_0592 3bfdee637874ff1789f48bd276cccb61 301 Pfam PF02881 SRP54-type protein, helical bundle domain 5 80 3.4E-14 T 23-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 TON_0592 3bfdee637874ff1789f48bd276cccb61 301 SMART SM00963 1 85 7.2E-17 T 23-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 TON_0592 3bfdee637874ff1789f48bd276cccb61 301 SMART SM00962 104 299 1.1E-112 T 23-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 TON_0592 3bfdee637874ff1789f48bd276cccb61 301 SUPERFAMILY SSF47364 1 89 2.09E-17 T 23-10-2018 IPR036225 SRP/SRP receptor, N-terminal Reactome: R-HSA-1799339 TON_0592 3bfdee637874ff1789f48bd276cccb61 301 SUPERFAMILY SSF52540 101 299 2.53E-56 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_1935 0e7e2ab376636cecd0fec252cbe81924 203 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 116 122 - T 23-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 TON_1935 0e7e2ab376636cecd0fec252cbe81924 203 Gene3D G3DSA:3.40.50.150 1 203 2.0E-66 T 23-10-2018 TON_1935 0e7e2ab376636cecd0fec252cbe81924 203 SUPERFAMILY SSF53335 3 200 9.3E-36 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TON_1935 0e7e2ab376636cecd0fec252cbe81924 203 Pfam PF05175 Methyltransferase small domain 40 128 2.4E-15 T 23-10-2018 IPR007848 Methyltransferase small domain GO:0008168 TON_1615 ea1024a3834f116eae0c8ba820141b85 150 SUPERFAMILY SSF54909 65 147 9.92E-17 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel TON_1615 ea1024a3834f116eae0c8ba820141b85 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 5 21 1.7E-13 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TON_1615 ea1024a3834f116eae0c8ba820141b85 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 21 32 1.7E-13 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TON_1615 ea1024a3834f116eae0c8ba820141b85 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 32 51 1.7E-13 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TON_1615 ea1024a3834f116eae0c8ba820141b85 150 Pfam PF01037 Lrp/AsnC ligand binding domain 78 142 1.8E-14 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain TON_1615 ea1024a3834f116eae0c8ba820141b85 150 Gene3D G3DSA:1.10.10.10 2 56 3.2E-20 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TON_1615 ea1024a3834f116eae0c8ba820141b85 150 Pfam PF13412 Winged helix-turn-helix DNA-binding 5 52 1.7E-15 T 23-10-2018 TON_1615 ea1024a3834f116eae0c8ba820141b85 150 SMART SM00344 5 114 4.7E-44 T 23-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 TON_1615 ea1024a3834f116eae0c8ba820141b85 150 SUPERFAMILY SSF46785 4 63 3.6E-12 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TON_1615 ea1024a3834f116eae0c8ba820141b85 150 Gene3D G3DSA:3.30.70.920 59 150 1.3E-22 T 23-10-2018 TON_1423 f3a33b112c5f675f65fc90b08709a293 444 PIRSF PIRSF018871 2 444 5.2E-125 T 23-10-2018 IPR016738 DNA double-strand break repair nuclease NurA-like TON_1423 f3a33b112c5f675f65fc90b08709a293 444 Pfam PF09376 NurA domain 44 409 2.8E-72 T 23-10-2018 IPR018977 NurA domain TON_1423 f3a33b112c5f675f65fc90b08709a293 444 SMART SM00933 43 409 3.5E-34 T 23-10-2018 IPR018977 NurA domain TON_0184 e0b2ed776cc2a9fefdd6b2ac74a97040 155 TIGRFAM TIGR02274 dCTP_deam: deoxycytidine triphosphate deaminase 8 151 1.8E-46 T 23-10-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 TON_0184 e0b2ed776cc2a9fefdd6b2ac74a97040 155 Gene3D G3DSA:2.70.40.10 1 155 1.2E-41 T 23-10-2018 IPR036157 dUTPase-like superfamily TON_0184 e0b2ed776cc2a9fefdd6b2ac74a97040 155 Pfam PF00692 dUTPase 42 136 1.1E-12 T 23-10-2018 IPR029054 dUTPase-like TON_0184 e0b2ed776cc2a9fefdd6b2ac74a97040 155 Hamap MF_00146 dCTP deaminase [dcd]. 1 152 25.443 T 23-10-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 TON_0184 e0b2ed776cc2a9fefdd6b2ac74a97040 155 SUPERFAMILY SSF51283 2 152 1.96E-38 T 23-10-2018 IPR036157 dUTPase-like superfamily TON_0753 9a5c0116e5d796e54c84c5f51057b401 130 SUPERFAMILY SSF52980 34 90 5.36E-5 T 23-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 TON_0753 9a5c0116e5d796e54c84c5f51057b401 130 Pfam PF03008 Archaea bacterial proteins of unknown function 4 99 2.2E-33 T 23-10-2018 IPR004256 Domain of unknown function DUF234, DEXX-box ATPase C-terminal TON_0951 b63d193acac5cecdf432bb3c2947db19 170 ProSitePatterns PS00469 Nucleoside diphosphate kinases active site. 120 128 - T 23-10-2018 IPR023005 Nucleoside diphosphate kinase, active site KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TON_0951 b63d193acac5cecdf432bb3c2947db19 170 SUPERFAMILY SSF54919 6 153 1.83E-60 T 23-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TON_0951 b63d193acac5cecdf432bb3c2947db19 170 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 6 144 36.459 T 23-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TON_0951 b63d193acac5cecdf432bb3c2947db19 170 PRINTS PR01243 Nucleoside diphosphate kinase signature 73 90 1.7E-42 T 23-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TON_0951 b63d193acac5cecdf432bb3c2947db19 170 PRINTS PR01243 Nucleoside diphosphate kinase signature 120 139 1.7E-42 T 23-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TON_0951 b63d193acac5cecdf432bb3c2947db19 170 PRINTS PR01243 Nucleoside diphosphate kinase signature 9 31 1.7E-42 T 23-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TON_0951 b63d193acac5cecdf432bb3c2947db19 170 PRINTS PR01243 Nucleoside diphosphate kinase signature 94 110 1.7E-42 T 23-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TON_0951 b63d193acac5cecdf432bb3c2947db19 170 PRINTS PR01243 Nucleoside diphosphate kinase signature 53 72 1.7E-42 T 23-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TON_0951 b63d193acac5cecdf432bb3c2947db19 170 Pfam PF00334 Nucleoside diphosphate kinase 7 144 2.7E-57 T 23-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TON_0951 b63d193acac5cecdf432bb3c2947db19 170 Gene3D G3DSA:3.30.70.141 1 159 2.3E-69 T 23-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TON_0951 b63d193acac5cecdf432bb3c2947db19 170 SMART SM00562 6 146 3.2E-82 T 23-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TON_0883 aa0c9a98835c5b47429034adb28c1660 229 Pfam PF00977 Histidine biosynthesis protein 2 218 5.1E-59 T 23-10-2018 IPR006062 Histidine biosynthesis GO:0000105 TON_0883 aa0c9a98835c5b47429034adb28c1660 229 SUPERFAMILY SSF51366 1 227 4.32E-54 T 23-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 TON_0883 aa0c9a98835c5b47429034adb28c1660 229 Hamap MF_01014 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [hisA]. 2 226 29.833 T 23-10-2018 IPR023016 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 TON_0883 aa0c9a98835c5b47429034adb28c1660 229 Gene3D G3DSA:3.20.20.70 3 229 2.2E-68 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TON_0883 aa0c9a98835c5b47429034adb28c1660 229 TIGRFAM TIGR00007 TIGR00007: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase 3 222 2.7E-72 T 23-10-2018 IPR006063 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase HisA GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 TON_0462 8e513bd0cbd5e043be9c7fc3ffa7822b 440 Gene3D G3DSA:3.40.50.300 18 349 2.2E-113 T 23-10-2018 TON_0462 8e513bd0cbd5e043be9c7fc3ffa7822b 440 SUPERFAMILY SSF52540 37 423 3.72E-40 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_0462 8e513bd0cbd5e043be9c7fc3ffa7822b 440 Gene3D G3DSA:2.40.50.360 119 243 2.2E-113 T 23-10-2018 TON_0462 8e513bd0cbd5e043be9c7fc3ffa7822b 440 SMART SM00382 62 353 8.0E-13 T 23-10-2018 IPR003593 AAA+ ATPase domain TON_0462 8e513bd0cbd5e043be9c7fc3ffa7822b 440 Pfam PF06068 TIP49 C-terminus 14 403 3.7E-161 T 23-10-2018 IPR010339 TIP49, C-terminal GO:0003678|GO:0005524 Reactome: R-HSA-171319|Reactome: R-HSA-3214847 TON_0462 8e513bd0cbd5e043be9c7fc3ffa7822b 440 SUPERFAMILY SSF50249 126 207 1.88E-19 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold TON_0462 8e513bd0cbd5e043be9c7fc3ffa7822b 440 Gene3D G3DSA:1.10.8.60 354 438 2.3E-25 T 23-10-2018 TON_0090 35f54786a37f7602aca243a4ef519df0 196 SUPERFAMILY SSF52540 1 188 1.02E-19 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_0090 35f54786a37f7602aca243a4ef519df0 196 Pfam PF13207 AAA domain 8 145 3.6E-37 T 23-10-2018 TON_0090 35f54786a37f7602aca243a4ef519df0 196 Gene3D G3DSA:3.40.50.300 3 189 1.8E-57 T 23-10-2018 TON_0090 35f54786a37f7602aca243a4ef519df0 196 Hamap MF_00234 Adenylate kinase [adkA]. 3 189 44.732 T 23-10-2018 IPR023477 Adenylate kinase AdkA GO:0004017 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 TON_1114 7c0373701097978c12329acfc610e1b3 797 SUPERFAMILY SSF52540 512 791 3.37E-80 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_1114 7c0373701097978c12329acfc610e1b3 797 SMART SM01073 8 92 6.1E-44 T 23-10-2018 IPR003338 CDC48, N-terminal subdomain TON_1114 7c0373701097978c12329acfc610e1b3 797 SMART SM00382 550 686 8.0E-24 T 23-10-2018 IPR003593 AAA+ ATPase domain TON_1114 7c0373701097978c12329acfc610e1b3 797 SMART SM00382 215 351 1.3E-25 T 23-10-2018 IPR003593 AAA+ ATPase domain TON_1114 7c0373701097978c12329acfc610e1b3 797 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 554 683 4.4E-48 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TON_1114 7c0373701097978c12329acfc610e1b3 797 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 219 348 2.3E-51 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TON_1114 7c0373701097978c12329acfc610e1b3 797 Gene3D G3DSA:2.40.40.20 1 91 2.6E-37 T 23-10-2018 TON_1114 7c0373701097978c12329acfc610e1b3 797 Gene3D G3DSA:3.40.50.300 165 366 4.9E-81 T 23-10-2018 TON_1114 7c0373701097978c12329acfc610e1b3 797 Pfam PF02933 Cell division protein 48 (CDC48), domain 2 108 169 4.9E-13 T 23-10-2018 IPR004201 CDC48, domain 2 TON_1114 7c0373701097978c12329acfc610e1b3 797 SUPERFAMILY SSF50692 1 91 1.37E-30 T 23-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily TON_1114 7c0373701097978c12329acfc610e1b3 797 Pfam PF02359 Cell division protein 48 (CDC48), N-terminal domain 8 92 1.6E-35 T 23-10-2018 IPR003338 CDC48, N-terminal subdomain TON_1114 7c0373701097978c12329acfc610e1b3 797 ProSitePatterns PS00674 AAA-protein family signature. 319 337 - T 23-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 TON_1114 7c0373701097978c12329acfc610e1b3 797 SUPERFAMILY SSF54585 92 184 1.67E-19 T 23-10-2018 IPR029067 CDC48 domain 2-like superfamily TON_1114 7c0373701097978c12329acfc610e1b3 797 Gene3D G3DSA:3.40.50.300 509 683 2.9E-74 T 23-10-2018 TON_1114 7c0373701097978c12329acfc610e1b3 797 ProSitePatterns PS00674 AAA-protein family signature. 654 672 - T 23-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 TON_1114 7c0373701097978c12329acfc610e1b3 797 Gene3D G3DSA:1.10.8.60 406 506 2.0E-18 T 23-10-2018 TON_1114 7c0373701097978c12329acfc610e1b3 797 SMART SM01072 107 170 3.8E-17 T 23-10-2018 IPR004201 CDC48, domain 2 TON_1114 7c0373701097978c12329acfc610e1b3 797 Pfam PF09336 Vps4 C terminal oligomerisation domain 750 790 7.3E-5 T 23-10-2018 IPR015415 Vps4 oligomerisation, C-terminal TON_1114 7c0373701097978c12329acfc610e1b3 797 Gene3D G3DSA:3.10.330.10 92 164 2.4E-6 T 23-10-2018 TON_1114 7c0373701097978c12329acfc610e1b3 797 SUPERFAMILY SSF52540 179 502 1.43E-70 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_1114 7c0373701097978c12329acfc610e1b3 797 Gene3D G3DSA:1.10.8.60 685 793 7.7E-34 T 23-10-2018 TON_1114 7c0373701097978c12329acfc610e1b3 797 TIGRFAM TIGR01243 CDC48: AAA family ATPase, CDC48 subfamily 7 793 0.0 T 23-10-2018 IPR005938 AAA ATPase, CDC48 family GO:0016787 Reactome: R-HSA-110320|Reactome: R-HSA-3371511|Reactome: R-HSA-382556|Reactome: R-HSA-532668|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5678895|Reactome: R-HSA-5689877|Reactome: R-HSA-5689896|Reactome: R-HSA-6798695|Reactome: R-HSA-8866654|Reactome: R-HSA-8876725 TON_1937 c1cd654297af8e029bc6b2c356af7f2b 265 Gene3D G3DSA:1.25.10.10 1 265 2.9E-115 T 23-10-2018 IPR011989 Armadillo-like helical TON_1937 c1cd654297af8e029bc6b2c356af7f2b 265 Pfam PF13646 HEAT repeats 77 146 1.5E-6 T 23-10-2018 TON_1937 c1cd654297af8e029bc6b2c356af7f2b 265 SUPERFAMILY SSF48371 31 218 2.08E-18 T 23-10-2018 IPR016024 Armadillo-type fold TON_0256 bfb460d68a3644c0e01db19ee580e0d5 378 Pfam PF01497 Periplasmic binding protein 106 299 2.7E-27 T 23-10-2018 IPR002491 ABC transporter periplasmic binding domain TON_0256 bfb460d68a3644c0e01db19ee580e0d5 378 Gene3D G3DSA:3.40.50.1980 31 178 1.3E-57 T 23-10-2018 TON_0256 bfb460d68a3644c0e01db19ee580e0d5 378 Gene3D G3DSA:3.40.50.1980 179 374 8.7E-89 T 23-10-2018 TON_0256 bfb460d68a3644c0e01db19ee580e0d5 378 SUPERFAMILY SSF53807 42 350 9.42E-58 T 23-10-2018 TON_0562 6de30c349909026afb15bb449e40c856 180 Gene3D G3DSA:3.40.50.300 1 180 2.8E-58 T 23-10-2018 TON_0562 6de30c349909026afb15bb449e40c856 180 Pfam PF13238 AAA domain 3 116 1.9E-20 T 23-10-2018 TON_0562 6de30c349909026afb15bb449e40c856 180 SUPERFAMILY SSF52540 1 153 7.78E-24 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_0562 6de30c349909026afb15bb449e40c856 180 Hamap MF_00039 Putative adenylate kinase. 1 160 25.472 T 23-10-2018 IPR020618 Adenylate kinase isoenzyme 6 GO:0004017|GO:0005524 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 TON_1214 a75f934a43749533c1d7fe455844b58e 219 SUPERFAMILY SSF118196 6 142 1.11E-37 T 23-10-2018 IPR036413 YaeB-like superfamily TON_1214 a75f934a43749533c1d7fe455844b58e 219 ProSitePatterns PS01318 TsaA-like domain signature. 74 85 - T 23-10-2018 IPR023368 Uncharacterised protein family UPF0066, conserved site TON_1214 a75f934a43749533c1d7fe455844b58e 219 Pfam PF01980 Uncharacterised protein family UPF0066 17 126 1.5E-29 T 23-10-2018 IPR023370 YaeB-like, N-terminal domain TON_1214 a75f934a43749533c1d7fe455844b58e 219 TIGRFAM TIGR00104 tRNA_TsaA: tRNA-Thr(GGU) m(6)t(6)A37 methyltransferase TsaA 15 130 6.4E-35 T 23-10-2018 IPR023370 YaeB-like, N-terminal domain TON_1214 a75f934a43749533c1d7fe455844b58e 219 Gene3D G3DSA:2.40.30.70 7 144 4.4E-30 T 23-10-2018 IPR036414 YaeB, N-terminal domain superfamily TON_1745 d0c7f905217e4beadf392104b4f82b76 230 Pfam PF02080 TrkA-C domain 153 221 1.5E-14 T 23-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 TON_1745 d0c7f905217e4beadf392104b4f82b76 230 SUPERFAMILY SSF51735 1 144 4.61E-38 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TON_1745 d0c7f905217e4beadf392104b4f82b76 230 Gene3D G3DSA:3.40.50.720 1 140 1.6E-41 T 23-10-2018 TON_1745 d0c7f905217e4beadf392104b4f82b76 230 Gene3D G3DSA:3.30.70.1450 141 223 1.1E-15 T 23-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 TON_1745 d0c7f905217e4beadf392104b4f82b76 230 PRINTS PR00335 TrkA potassium uptake protein signature 60 70 6.2E-14 T 23-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 TON_1745 d0c7f905217e4beadf392104b4f82b76 230 PRINTS PR00335 TrkA potassium uptake protein signature 73 87 6.2E-14 T 23-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 TON_1745 d0c7f905217e4beadf392104b4f82b76 230 PRINTS PR00335 TrkA potassium uptake protein signature 2 16 6.2E-14 T 23-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 TON_1745 d0c7f905217e4beadf392104b4f82b76 230 PRINTS PR00335 TrkA potassium uptake protein signature 19 33 6.2E-14 T 23-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 TON_1745 d0c7f905217e4beadf392104b4f82b76 230 PRINTS PR00335 TrkA potassium uptake protein signature 49 59 6.2E-14 T 23-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 TON_1745 d0c7f905217e4beadf392104b4f82b76 230 Pfam PF02254 TrkA-N domain 3 124 4.6E-29 T 23-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 TON_1745 d0c7f905217e4beadf392104b4f82b76 230 SUPERFAMILY SSF116726 135 221 1.03E-12 T 23-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 TON_0613 f1792051adcb3fa5f33703005a1fc94d 1389 Gene3D G3DSA:3.10.28.10 524 734 1.6E-30 T 23-10-2018 IPR027434 Homing endonuclease TON_0613 f1792051adcb3fa5f33703005a1fc94d 1389 SUPERFAMILY SSF55608 632 735 5.61E-15 T 23-10-2018 IPR027434 Homing endonuclease TON_0613 f1792051adcb3fa5f33703005a1fc94d 1389 Gene3D G3DSA:2.170.16.10 795 871 1.6E-6 T 23-10-2018 TON_0613 f1792051adcb3fa5f33703005a1fc94d 1389 SMART SM00306 346 443 2.6E-14 T 23-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TON_0613 f1792051adcb3fa5f33703005a1fc94d 1389 Pfam PF14528 LAGLIDADG-like domain 645 733 1.2E-11 T 23-10-2018 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 TON_0613 f1792051adcb3fa5f33703005a1fc94d 1389 Gene3D G3DSA:3.40.50.300 872 932 1.2E-7 T 23-10-2018 TON_0613 f1792051adcb3fa5f33703005a1fc94d 1389 Pfam PF08494 DEAD/H associated 1165 1353 1.5E-53 T 23-10-2018 IPR013701 DEAD/H associated GO:0005524|GO:0016818 TON_0613 f1792051adcb3fa5f33703005a1fc94d 1389 Pfam PF00270 DEAD/DEAH box helicase 38 222 3.4E-26 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 TON_0613 f1792051adcb3fa5f33703005a1fc94d 1389 SUPERFAMILY SSF52540 268 937 6.59E-19 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_0613 f1792051adcb3fa5f33703005a1fc94d 1389 SMART SM00490 833 911 0.0091 T 23-10-2018 IPR001650 Helicase, C-terminal TON_0613 f1792051adcb3fa5f33703005a1fc94d 1389 SUPERFAMILY SSF51294 348 870 1.39E-31 T 23-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TON_0613 f1792051adcb3fa5f33703005a1fc94d 1389 SMART SM00305 831 876 1.2E-5 T 23-10-2018 IPR003586 Hint domain C-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TON_0613 f1792051adcb3fa5f33703005a1fc94d 1389 Gene3D G3DSA:3.40.50.300 263 350 1.1E-9 T 23-10-2018 TON_0613 f1792051adcb3fa5f33703005a1fc94d 1389 Gene3D G3DSA:3.40.50.300 16 238 4.1E-53 T 23-10-2018 TON_0613 f1792051adcb3fa5f33703005a1fc94d 1389 Pfam PF00271 Helicase conserved C-terminal domain 871 907 4.0E-5 T 23-10-2018 IPR001650 Helicase, C-terminal TON_0613 f1792051adcb3fa5f33703005a1fc94d 1389 Gene3D G3DSA:2.170.16.10 353 464 1.5E-11 T 23-10-2018 TON_0613 f1792051adcb3fa5f33703005a1fc94d 1389 SMART SM00382 50 336 0.0019 T 23-10-2018 IPR003593 AAA+ ATPase domain TON_0613 f1792051adcb3fa5f33703005a1fc94d 1389 PRINTS PR00379 Intein signature 930 939 2.0E-13 T 23-10-2018 IPR006142 Intein GO:0016539 TON_0613 f1792051adcb3fa5f33703005a1fc94d 1389 PRINTS PR00379 Intein signature 406 419 2.0E-13 T 23-10-2018 IPR006142 Intein GO:0016539 TON_0613 f1792051adcb3fa5f33703005a1fc94d 1389 PRINTS PR00379 Intein signature 676 691 2.0E-13 T 23-10-2018 IPR006142 Intein GO:0016539 TON_0613 f1792051adcb3fa5f33703005a1fc94d 1389 PRINTS PR00379 Intein signature 645 657 2.0E-13 T 23-10-2018 IPR006142 Intein GO:0016539 TON_0613 f1792051adcb3fa5f33703005a1fc94d 1389 PRINTS PR00379 Intein signature 550 562 2.0E-13 T 23-10-2018 IPR006142 Intein GO:0016539 TON_0613 f1792051adcb3fa5f33703005a1fc94d 1389 SUPERFAMILY SSF52540 23 231 1.61E-39 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_0613 f1792051adcb3fa5f33703005a1fc94d 1389 SMART SM00487 33 261 8.4E-34 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TON_0613 f1792051adcb3fa5f33703005a1fc94d 1389 Pfam PF14890 Intein splicing domain 391 867 3.7E-17 T 23-10-2018 TON_0517 64745131603f51dfe1a9e9008d43f763 151 Gene3D G3DSA:1.10.287.10 83 151 4.4E-32 T 23-10-2018 TON_0517 64745131603f51dfe1a9e9008d43f763 151 Hamap MF_01343_A 30S ribosomal protein S15 [rpsO]. 3 149 37.711 T 23-10-2018 IPR023029 Ribosomal protein S15P Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0517 64745131603f51dfe1a9e9008d43f763 151 SMART SM01387 70 149 1.6E-26 T 23-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TON_0517 64745131603f51dfe1a9e9008d43f763 151 SUPERFAMILY SSF47060 66 142 8.54E-25 T 23-10-2018 IPR009068 S15/NS1, RNA-binding TON_0517 64745131603f51dfe1a9e9008d43f763 151 Pfam PF00312 Ribosomal protein S15 73 148 8.5E-20 T 23-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TON_0517 64745131603f51dfe1a9e9008d43f763 151 ProSitePatterns PS00362 Ribosomal protein S15 signature. 98 128 - T 23-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TON_0517 64745131603f51dfe1a9e9008d43f763 151 Gene3D G3DSA:1.10.8.1030 36 82 4.5E-21 T 23-10-2018 TON_0517 64745131603f51dfe1a9e9008d43f763 151 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 91 132 0.003 T 23-10-2018 TON_0517 64745131603f51dfe1a9e9008d43f763 151 SMART SM01386 1 60 3.0E-34 T 23-10-2018 IPR012606 Ribosomal protein S13/S15, N-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0517 64745131603f51dfe1a9e9008d43f763 151 Pfam PF08069 Ribosomal S13/S15 N-terminal domain 1 60 8.1E-27 T 23-10-2018 IPR012606 Ribosomal protein S13/S15, N-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0961 dbb19d661d7499cf097ad181ccdfe7b2 430 SUPERFAMILY SSF50249 4 100 3.43E-25 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold TON_0961 dbb19d661d7499cf097ad181ccdfe7b2 430 Gene3D G3DSA:3.30.930.10 105 430 2.9E-116 T 23-10-2018 TON_0961 dbb19d661d7499cf097ad181ccdfe7b2 430 SUPERFAMILY SSF55681 111 425 2.14E-87 T 23-10-2018 TON_0961 dbb19d661d7499cf097ad181ccdfe7b2 430 Pfam PF01336 OB-fold nucleic acid binding domain 19 97 3.3E-14 T 23-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 TON_0961 dbb19d661d7499cf097ad181ccdfe7b2 430 TIGRFAM TIGR00457 asnS: asparagine--tRNA ligase 14 429 5.9E-127 T 23-10-2018 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22 TON_0961 dbb19d661d7499cf097ad181ccdfe7b2 430 PRINTS PR01042 Aspartyl-tRNA synthetase signature 181 193 1.7E-14 T 23-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 TON_0961 dbb19d661d7499cf097ad181ccdfe7b2 430 PRINTS PR01042 Aspartyl-tRNA synthetase signature 345 361 1.7E-14 T 23-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 TON_0961 dbb19d661d7499cf097ad181ccdfe7b2 430 PRINTS PR01042 Aspartyl-tRNA synthetase signature 385 399 1.7E-14 T 23-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 TON_0961 dbb19d661d7499cf097ad181ccdfe7b2 430 PRINTS PR01042 Aspartyl-tRNA synthetase signature 197 210 1.7E-14 T 23-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 TON_0961 dbb19d661d7499cf097ad181ccdfe7b2 430 Pfam PF00152 tRNA synthetases class II (D, K and N) 111 424 1.7E-86 T 23-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 TON_0961 dbb19d661d7499cf097ad181ccdfe7b2 430 Gene3D G3DSA:2.40.50.140 1 102 1.6E-29 T 23-10-2018 TON_0388 8df510d767651955076b49c44d3cc027 325 Gene3D G3DSA:3.30.230.10 16 145 1.0E-9 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TON_0388 8df510d767651955076b49c44d3cc027 325 Pfam PF08544 GHMP kinases C terminal 203 272 3.2E-4 T 23-10-2018 IPR013750 GHMP kinase, C-terminal domain TON_0388 8df510d767651955076b49c44d3cc027 325 PIRSF PIRSF004884 1 309 6.7E-103 T 23-10-2018 IPR004422 GHMP kinase group 1 KEGG: 00790+2.4.2.54|MetaCyc: PWY-6148 TON_0388 8df510d767651955076b49c44d3cc027 325 TIGRFAM TIGR00144 beta_RFAP_syn: beta-ribofuranosylaminobenzene 5'-phosphate synthase family 1 306 7.1E-50 T 23-10-2018 IPR004422 GHMP kinase group 1 KEGG: 00790+2.4.2.54|MetaCyc: PWY-6148 TON_0388 8df510d767651955076b49c44d3cc027 325 SUPERFAMILY SSF54211 1 150 3.87E-18 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TON_0388 8df510d767651955076b49c44d3cc027 325 Pfam PF00288 GHMP kinases N terminal domain 76 136 5.3E-5 T 23-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 TON_0203 84e6f688b249def955a619f9443e9501 496 Gene3D G3DSA:3.30.9.10 90 321 1.5E-116 T 23-10-2018 TON_0203 84e6f688b249def955a619f9443e9501 496 Pfam PF04324 BFD-like [2Fe-2S] binding domain 406 464 1.3E-14 T 23-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain TON_0203 84e6f688b249def955a619f9443e9501 496 Gene3D G3DSA:1.10.10.1100 394 473 2.7E-17 T 23-10-2018 TON_0203 84e6f688b249def955a619f9443e9501 496 Pfam PF01266 FAD dependent oxidoreductase 4 360 6.6E-69 T 23-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 TON_0203 84e6f688b249def955a619f9443e9501 496 Gene3D G3DSA:3.50.50.60 5 354 1.5E-116 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TON_0203 84e6f688b249def955a619f9443e9501 496 SUPERFAMILY SSF51905 3 415 2.85E-58 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TON_0203 84e6f688b249def955a619f9443e9501 496 SUPERFAMILY SSF54373 223 318 2.09E-7 T 23-10-2018 TON_0093 f74b8e564b10e5a0912dff37be88cbba 197 Hamap MF_00239 Cytidylate kinase [cmk]. 6 178 47.32 T 23-10-2018 IPR011892 Cytidylate kinase, putative GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 TON_0093 f74b8e564b10e5a0912dff37be88cbba 197 Gene3D G3DSA:3.40.50.300 2 177 5.3E-44 T 23-10-2018 TON_0093 f74b8e564b10e5a0912dff37be88cbba 197 TIGRFAM TIGR02173 cyt_kin_arch: putative cytidylate kinase 6 175 5.1E-62 T 23-10-2018 IPR011892 Cytidylate kinase, putative GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 TON_0093 f74b8e564b10e5a0912dff37be88cbba 197 SUPERFAMILY SSF52540 3 176 9.87E-22 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_0093 f74b8e564b10e5a0912dff37be88cbba 197 Pfam PF13189 Cytidylate kinase-like family 7 160 9.9E-24 T 23-10-2018 TON_0040 43325dc8e1ba3c94cc36dedfa5655bc0 128 Pfam PF04277 Oxaloacetate decarboxylase, gamma chain 9 86 9.9E-14 T 23-10-2018 IPR005899 Sodium ion-translocating decarboxylase GO:0008948|GO:0015081|GO:0016020|GO:0036376 KEGG: 00620+4.1.1.3 TON_0040 43325dc8e1ba3c94cc36dedfa5655bc0 128 TIGRFAM TIGR01195 oadG_fam: sodium pump decarboxylases, gamma subunit 7 87 1.4E-11 T 23-10-2018 IPR005899 Sodium ion-translocating decarboxylase GO:0008948|GO:0015081|GO:0016020|GO:0036376 KEGG: 00620+4.1.1.3 TON_1313 53df3dba7b85186837cba4293064c2c3 459 SUPERFAMILY SSF52210 132 288 7.33E-48 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TON_1313 53df3dba7b85186837cba4293064c2c3 459 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 150 287 6.7E-59 T 23-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain TON_1313 53df3dba7b85186837cba4293064c2c3 459 SUPERFAMILY SSF51735 3 138 3.1E-37 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TON_1313 53df3dba7b85186837cba4293064c2c3 459 Gene3D G3DSA:3.40.50.261 130 289 2.5E-64 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TON_1313 53df3dba7b85186837cba4293064c2c3 459 Pfam PF13380 CoA binding domain 10 135 6.1E-25 T 23-10-2018 IPR003781 CoA-binding GO:0048037 TON_1313 53df3dba7b85186837cba4293064c2c3 459 Gene3D G3DSA:3.40.50.720 3 129 1.8E-44 T 23-10-2018 TON_1313 53df3dba7b85186837cba4293064c2c3 459 Gene3D G3DSA:3.40.50.261 290 458 1.6E-64 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TON_1313 53df3dba7b85186837cba4293064c2c3 459 SUPERFAMILY SSF52210 292 448 2.62E-39 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TON_1313 53df3dba7b85186837cba4293064c2c3 459 SMART SM00881 6 100 5.1E-32 T 23-10-2018 IPR003781 CoA-binding GO:0048037 TON_1569 687afb5dd801708507125b1414ce6aaf 584 ProSitePatterns PS00542 Respiratory chain NADH dehydrogenase 30 Kd subunit signature. 138 159 - T 23-10-2018 IPR020396 NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_1569 687afb5dd801708507125b1414ce6aaf 584 SUPERFAMILY SSF143243 28 210 1.57E-41 T 23-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_1569 687afb5dd801708507125b1414ce6aaf 584 Gene3D G3DSA:3.30.460.80 5 157 5.9E-21 T 23-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_1569 687afb5dd801708507125b1414ce6aaf 584 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 54 178 9.8E-27 T 23-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_1569 687afb5dd801708507125b1414ce6aaf 584 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 108 164 1.0E-10 T 23-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_1569 687afb5dd801708507125b1414ce6aaf 584 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 315 554 1.4E-58 T 23-10-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_1569 687afb5dd801708507125b1414ce6aaf 584 Gene3D G3DSA:1.10.645.20 197 554 3.8E-126 T 23-10-2018 IPR038290 NADH-quinone oxidoreductase, subunit D superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_1569 687afb5dd801708507125b1414ce6aaf 584 Pfam PF00374 Nickel-dependent hydrogenase 235 306 1.8E-16 T 23-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 TON_1569 687afb5dd801708507125b1414ce6aaf 584 SUPERFAMILY SSF56762 208 554 2.75E-118 T 23-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_0727 b5b83d320152480de2a12c8c6fb37699 591 ProSitePatterns PS00211 ABC transporters family signature. 211 225 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TON_0727 b5b83d320152480de2a12c8c6fb37699 591 Pfam PF04068 Possible Fer4-like domain in RNase L inhibitor, RLI 1 32 9.1E-12 T 23-10-2018 IPR007209 RNase L inhibitor RLI, possible metal-binding domain TON_0727 b5b83d320152480de2a12c8c6fb37699 591 PRINTS PR01868 ABC transporter family E signature 48 72 3.5E-63 T 23-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 TON_0727 b5b83d320152480de2a12c8c6fb37699 591 PRINTS PR01868 ABC transporter family E signature 103 128 3.5E-63 T 23-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 TON_0727 b5b83d320152480de2a12c8c6fb37699 591 PRINTS PR01868 ABC transporter family E signature 150 176 3.5E-63 T 23-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 TON_0727 b5b83d320152480de2a12c8c6fb37699 591 PRINTS PR01868 ABC transporter family E signature 20 35 3.5E-63 T 23-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 TON_0727 b5b83d320152480de2a12c8c6fb37699 591 PRINTS PR01868 ABC transporter family E signature 75 95 3.5E-63 T 23-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 TON_0727 b5b83d320152480de2a12c8c6fb37699 591 PRINTS PR01868 ABC transporter family E signature 134 150 3.5E-63 T 23-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 TON_0727 b5b83d320152480de2a12c8c6fb37699 591 Pfam PF00037 4Fe-4S binding domain 45 67 7.0E-7 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TON_0727 b5b83d320152480de2a12c8c6fb37699 591 SUPERFAMILY SSF52540 344 529 6.83E-41 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_0727 b5b83d320152480de2a12c8c6fb37699 591 Pfam PF00005 ABC transporter 96 238 1.9E-17 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TON_0727 b5b83d320152480de2a12c8c6fb37699 591 Pfam PF00005 ABC transporter 360 482 3.1E-21 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TON_0727 b5b83d320152480de2a12c8c6fb37699 591 Gene3D G3DSA:3.40.50.300 1 326 7.5E-104 T 23-10-2018 TON_0727 b5b83d320152480de2a12c8c6fb37699 591 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 51 62 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TON_0727 b5b83d320152480de2a12c8c6fb37699 591 SMART SM00382 98 286 8.6E-11 T 23-10-2018 IPR003593 AAA+ ATPase domain TON_0727 b5b83d320152480de2a12c8c6fb37699 591 SMART SM00382 363 531 7.3E-11 T 23-10-2018 IPR003593 AAA+ ATPase domain TON_0727 b5b83d320152480de2a12c8c6fb37699 591 Gene3D G3DSA:3.40.50.300 327 589 5.8E-68 T 23-10-2018 TON_0727 b5b83d320152480de2a12c8c6fb37699 591 SUPERFAMILY SSF52540 96 285 1.15E-34 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_0727 b5b83d320152480de2a12c8c6fb37699 591 SUPERFAMILY SSF54862 4 124 6.52E-24 T 23-10-2018 TON_1213 f84ca3966ada18d7aa02a04e0574cd3c 312 SUPERFAMILY SSF52129 80 255 1.36E-11 T 23-10-2018 IPR029030 Caspase-like domain superfamily TON_1213 f84ca3966ada18d7aa02a04e0574cd3c 312 Gene3D G3DSA:3.40.50.1460 81 300 3.5E-40 T 23-10-2018 TON_1213 f84ca3966ada18d7aa02a04e0574cd3c 312 Pfam PF00656 Caspase domain 83 234 2.5E-22 T 23-10-2018 TON_1345 a8357df8cecb2e3d8d0a89f780b96aa9 269 Pfam PF02535 ZIP Zinc transporter 122 264 1.6E-20 T 23-10-2018 IPR003689 Zinc/iron permease GO:0016020|GO:0030001|GO:0046873|GO:0055085 TON_1270 1f78f33d8c1a9a4efab8b2ef0c82e31e 225 SUPERFAMILY SSF53633 1 224 3.67E-52 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily TON_1270 1f78f33d8c1a9a4efab8b2ef0c82e31e 225 Hamap MF_01220_A Uridylate kinase [pyrH]. 1 225 35.174 T 23-10-2018 IPR011818 Uridylate kinase, archaeal/spirochete, putative GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 TON_1270 1f78f33d8c1a9a4efab8b2ef0c82e31e 225 Pfam PF00696 Amino acid kinase family 1 202 5.1E-35 T 23-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 TON_1270 1f78f33d8c1a9a4efab8b2ef0c82e31e 225 PIRSF PIRSF005650 1 225 2.6E-61 T 23-10-2018 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 TON_1270 1f78f33d8c1a9a4efab8b2ef0c82e31e 225 TIGRFAM TIGR02076 pyrH_arch: putative uridylate kinase 3 224 3.3E-87 T 23-10-2018 IPR011818 Uridylate kinase, archaeal/spirochete, putative GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 TON_1270 1f78f33d8c1a9a4efab8b2ef0c82e31e 225 Gene3D G3DSA:3.40.1160.10 1 225 2.0E-62 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily TON_0880 fa87bc8b2ef07b4c896902d448f2012b 377 PRINTS PR00083 Histidinol dehydrogenase signature 141 167 2.7E-94 T 23-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 TON_0880 fa87bc8b2ef07b4c896902d448f2012b 377 PRINTS PR00083 Histidinol dehydrogenase signature 170 195 2.7E-94 T 23-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 TON_0880 fa87bc8b2ef07b4c896902d448f2012b 377 PRINTS PR00083 Histidinol dehydrogenase signature 311 329 2.7E-94 T 23-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 TON_0880 fa87bc8b2ef07b4c896902d448f2012b 377 PRINTS PR00083 Histidinol dehydrogenase signature 80 107 2.7E-94 T 23-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 TON_0880 fa87bc8b2ef07b4c896902d448f2012b 377 PRINTS PR00083 Histidinol dehydrogenase signature 107 133 2.7E-94 T 23-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 TON_0880 fa87bc8b2ef07b4c896902d448f2012b 377 PRINTS PR00083 Histidinol dehydrogenase signature 9 33 2.7E-94 T 23-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 TON_0880 fa87bc8b2ef07b4c896902d448f2012b 377 PRINTS PR00083 Histidinol dehydrogenase signature 199 220 2.7E-94 T 23-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 TON_0880 fa87bc8b2ef07b4c896902d448f2012b 377 PRINTS PR00083 Histidinol dehydrogenase signature 221 240 2.7E-94 T 23-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 TON_0880 fa87bc8b2ef07b4c896902d448f2012b 377 PRINTS PR00083 Histidinol dehydrogenase signature 270 295 2.7E-94 T 23-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 TON_0880 fa87bc8b2ef07b4c896902d448f2012b 377 Gene3D G3DSA:3.40.50.1980 250 321 4.6E-20 T 23-10-2018 TON_0880 fa87bc8b2ef07b4c896902d448f2012b 377 ProSitePatterns PS00611 Histidinol dehydrogenase signature. 199 231 - T 23-10-2018 IPR001692 Histidinol dehydrogenase, conserved site GO:0000105|GO:0004399|GO:0055114 KEGG: 00340+1.1.1.23 TON_0880 fa87bc8b2ef07b4c896902d448f2012b 377 Gene3D G3DSA:3.40.50.1980 2 212 6.4E-69 T 23-10-2018 TON_0880 fa87bc8b2ef07b4c896902d448f2012b 377 SUPERFAMILY SSF53720 8 376 3.53E-57 T 23-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 TON_0880 fa87bc8b2ef07b4c896902d448f2012b 377 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 1 377 36.131 T 23-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 TON_0880 fa87bc8b2ef07b4c896902d448f2012b 377 Pfam PF00815 Histidinol dehydrogenase 5 376 4.1E-130 T 23-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 TON_0880 fa87bc8b2ef07b4c896902d448f2012b 377 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 9 251 3.2E-92 T 23-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 TON_1136 f627cb86c81a2a7c16c22a7bd653eb19 275 Gene3D G3DSA:3.40.50.10860 8 256 4.9E-93 T 23-10-2018 TON_1136 f627cb86c81a2a7c16c22a7bd653eb19 275 Hamap MF_00222 Shikimate dehydrogenase (NADP(+)) [aroE]. 5 265 35.806 T 23-10-2018 IPR022893 Shikimate dehydrogenase family GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 TON_1136 f627cb86c81a2a7c16c22a7bd653eb19 275 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 10 90 2.5E-27 T 23-10-2018 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 TON_1136 f627cb86c81a2a7c16c22a7bd653eb19 275 Gene3D G3DSA:3.40.50.720 102 233 4.9E-93 T 23-10-2018 TON_1136 f627cb86c81a2a7c16c22a7bd653eb19 275 TIGRFAM TIGR00507 aroE: shikimate dehydrogenase 7 266 6.6E-82 T 23-10-2018 IPR011342 Shikimate dehydrogenase GO:0004764|GO:0019632|GO:0050661|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 TON_1136 f627cb86c81a2a7c16c22a7bd653eb19 275 SUPERFAMILY SSF53223 3 102 2.71E-34 T 23-10-2018 TON_1136 f627cb86c81a2a7c16c22a7bd653eb19 275 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 110 186 9.9E-13 T 23-10-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase TON_1136 f627cb86c81a2a7c16c22a7bd653eb19 275 SUPERFAMILY SSF51735 103 264 1.32E-43 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TON_0426 cd49d6353b2fc8f88972f0f09ec06e8e 136 Hamap MF_00085 Translation initiation factor 5A [eif5a]. 3 133 34.227 T 23-10-2018 IPR022847 Translation elongation factor IF5A, archaeal TON_0426 cd49d6353b2fc8f88972f0f09ec06e8e 136 Pfam PF01287 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold 70 134 1.0E-10 T 23-10-2018 IPR020189 Translation elongation factor, IF5A C-terminal GO:0003723|GO:0003746|GO:0006452|GO:0043022|GO:0045901|GO:0045905 TON_0426 cd49d6353b2fc8f88972f0f09ec06e8e 136 TIGRFAM TIGR00037 eIF_5A: translation elongation factor IF5A 4 134 2.3E-46 T 23-10-2018 IPR001884 Translation elongation factor IF5A-like GO:0003723|GO:0003746|GO:0043022|GO:0045901 TON_0426 cd49d6353b2fc8f88972f0f09ec06e8e 136 SUPERFAMILY SSF50249 71 132 1.41E-13 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold TON_0426 cd49d6353b2fc8f88972f0f09ec06e8e 136 SMART SM01376 70 134 2.5E-15 T 23-10-2018 IPR020189 Translation elongation factor, IF5A C-terminal GO:0003723|GO:0003746|GO:0006452|GO:0043022|GO:0045901|GO:0045905 TON_0426 cd49d6353b2fc8f88972f0f09ec06e8e 136 Gene3D G3DSA:2.40.50.140 71 135 1.9E-29 T 23-10-2018 TON_0426 cd49d6353b2fc8f88972f0f09ec06e8e 136 ProSitePatterns PS00302 Eukaryotic initiation factor 5A hypusine signature. 35 42 - T 23-10-2018 IPR019769 Translation elongation factor, IF5A, hypusine site GO:0003723|GO:0003746|GO:0043022|GO:0045901|GO:0045905 TON_0426 cd49d6353b2fc8f88972f0f09ec06e8e 136 SUPERFAMILY SSF50104 5 78 8.53E-20 T 23-10-2018 IPR008991 Translation protein SH3-like domain superfamily TON_0426 cd49d6353b2fc8f88972f0f09ec06e8e 136 Gene3D G3DSA:2.30.30.30 1 70 1.7E-27 T 23-10-2018 IPR014722 Ribosomal protein L2, domain 2 TON_0426 cd49d6353b2fc8f88972f0f09ec06e8e 136 PIRSF PIRSF003025 1 136 7.6E-44 T 23-10-2018 IPR001884 Translation elongation factor IF5A-like GO:0003723|GO:0003746|GO:0043022|GO:0045901 TON_1776 d081ce33b8ef71aa1f55d9a7538cdebd 283 SUPERFAMILY SSF103481 184 280 7.06E-14 T 23-10-2018 TON_1776 d081ce33b8ef71aa1f55d9a7538cdebd 283 SUPERFAMILY SSF103481 43 140 3.14E-15 T 23-10-2018 TON_1776 d081ce33b8ef71aa1f55d9a7538cdebd 283 Pfam PF00892 EamA-like transporter family 5 137 3.7E-18 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TON_1776 d081ce33b8ef71aa1f55d9a7538cdebd 283 Pfam PF00892 EamA-like transporter family 150 276 2.4E-19 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TON_1803 e42c664a3d322b34cd436b74689bcad3 1065 Hamap MF_02003 Isoleucine--tRNA ligase [ileS]. 3 1059 13.783 T 23-10-2018 IPR023586 Isoleucine-tRNA ligase, type 2 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 TON_1803 e42c664a3d322b34cd436b74689bcad3 1065 Gene3D G3DSA:3.90.740.10 199 405 6.0E-233 T 23-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 TON_1803 e42c664a3d322b34cd436b74689bcad3 1065 Pfam PF08264 Anticodon-binding domain of tRNA 711 862 3.0E-38 T 23-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 TON_1803 e42c664a3d322b34cd436b74689bcad3 1065 Gene3D G3DSA:3.40.50.620 16 651 6.0E-233 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TON_1803 e42c664a3d322b34cd436b74689bcad3 1065 SUPERFAMILY SSF47323 984 1050 3.2E-6 T 23-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 TON_1803 e42c664a3d322b34cd436b74689bcad3 1065 Gene3D G3DSA:1.10.730.10 670 853 2.8E-55 T 23-10-2018 TON_1803 e42c664a3d322b34cd436b74689bcad3 1065 SUPERFAMILY SSF50677 201 401 2.62E-56 T 23-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 TON_1803 e42c664a3d322b34cd436b74689bcad3 1065 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 10 875 0.0 T 23-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 TON_1803 e42c664a3d322b34cd436b74689bcad3 1065 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 21 664 2.4E-189 T 23-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 TON_1803 e42c664a3d322b34cd436b74689bcad3 1065 SUPERFAMILY SSF52374 3 674 3.58E-134 T 23-10-2018 TON_1803 e42c664a3d322b34cd436b74689bcad3 1065 SUPERFAMILY SSF47323 676 912 5.79E-61 T 23-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 TON_1803 e42c664a3d322b34cd436b74689bcad3 1065 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 49 60 - T 23-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 TON_1803 e42c664a3d322b34cd436b74689bcad3 1065 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 42 53 2.8E-30 T 23-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 TON_1803 e42c664a3d322b34cd436b74689bcad3 1065 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 545 558 2.8E-30 T 23-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 TON_1803 e42c664a3d322b34cd436b74689bcad3 1065 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 584 593 2.8E-30 T 23-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 TON_1803 e42c664a3d322b34cd436b74689bcad3 1065 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 223 246 2.8E-30 T 23-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 TON_1803 e42c664a3d322b34cd436b74689bcad3 1065 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 399 414 2.8E-30 T 23-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 TON_0349 323231ec9f37642b7bb2d6193ed21953 95 Gene3D G3DSA:1.20.1270.90 4 84 3.4E-25 T 23-10-2018 TON_0349 323231ec9f37642b7bb2d6193ed21953 95 Pfam PF04010 Protein of unknown function (DUF357) 12 84 5.0E-30 T 23-10-2018 IPR023140 Domain of unknown function DUF357 TON_0349 323231ec9f37642b7bb2d6193ed21953 95 SUPERFAMILY SSF158372 4 85 5.49E-26 T 23-10-2018 IPR036809 AF1782-like superfamily TON_1375 4c084da72a81afb737a31fbc3092f974 282 Gene3D G3DSA:2.40.30.10 1 91 1.7E-10 T 23-10-2018 TON_1375 4c084da72a81afb737a31fbc3092f974 282 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 214 250 4.1E-11 T 23-10-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain TON_1375 4c084da72a81afb737a31fbc3092f974 282 SUPERFAMILY SSF52343 115 249 4.32E-11 T 23-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain TON_1375 4c084da72a81afb737a31fbc3092f974 282 Gene3D G3DSA:3.40.50.80 99 204 8.4E-13 T 23-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain TON_1375 4c084da72a81afb737a31fbc3092f974 282 SUPERFAMILY SSF63380 3 91 1.34E-11 T 23-10-2018 IPR017938 Riboflavin synthase-like beta-barrel TON_1375 4c084da72a81afb737a31fbc3092f974 282 PIRSF PIRSF006816 1 256 1.3E-38 T 23-10-2018 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 TON_0246 5986ff4f306fa93b3306ea2a31ff6b71 453 PIRSF PIRSF015883 7 453 1.4E-157 T 23-10-2018 IPR015990 ADP-specific phosphofructokinase/glucokinase, archaeal GO:0000287|GO:0006096|GO:0016773 TON_0246 5986ff4f306fa93b3306ea2a31ff6b71 453 SUPERFAMILY SSF53613 2 452 1.5E-151 T 23-10-2018 IPR029056 Ribokinase-like TON_0246 5986ff4f306fa93b3306ea2a31ff6b71 453 Pfam PF04587 ADP-specific Phosphofructokinase/Glucokinase conserved region 23 447 1.7E-94 T 23-10-2018 IPR007666 ADP-specific phosphofructokinase/glucokinase GO:0005975|GO:0016773 Reactome: R-HSA-70171 TON_0246 5986ff4f306fa93b3306ea2a31ff6b71 453 Hamap MF_00809 ADP-dependent glucokinase [glkA]. 1 453 58.772 T 23-10-2018 IPR031299 ADP-dependent glucokinase, archaeal KEGG: 00010+2.7.1.147|MetaCyc: PWY-6855 TON_0246 5986ff4f306fa93b3306ea2a31ff6b71 453 Gene3D G3DSA:3.30.1110.20 31 203 4.8E-149 T 23-10-2018 TON_0246 5986ff4f306fa93b3306ea2a31ff6b71 453 Gene3D G3DSA:3.40.1190.20 24 447 4.8E-149 T 23-10-2018 IPR029056 Ribokinase-like TON_0777 667d658da9accc8f7fd123e97c4379e2 223 SUPERFAMILY SSF53335 2 196 7.23E-50 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TON_0777 667d658da9accc8f7fd123e97c4379e2 223 Gene3D G3DSA:3.40.50.150 1 190 4.4E-53 T 23-10-2018 TON_0777 667d658da9accc8f7fd123e97c4379e2 223 Pfam PF08241 Methyltransferase domain 44 132 2.2E-27 T 23-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 TON_1110 ee44336a48eabc3cc54c243c9bc30c9e 562 Pfam PF01642 Methylmalonyl-CoA mutase 39 554 4.6E-239 T 23-10-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 TON_1110 ee44336a48eabc3cc54c243c9bc30c9e 562 Gene3D G3DSA:3.20.20.240 1 562 5.8E-266 T 23-10-2018 TON_1110 ee44336a48eabc3cc54c243c9bc30c9e 562 TIGRFAM TIGR00641 acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain 37 560 9.2E-289 T 23-10-2018 IPR006098 Methylmalonyl-CoA mutase, alpha chain, catalytic GO:0004494|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 TON_1110 ee44336a48eabc3cc54c243c9bc30c9e 562 SUPERFAMILY SSF51703 10 556 6.08E-229 T 23-10-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 TON_1230 c9fb56eab8f6464c3de435c450798588 67 Pfam PF00833 Ribosomal S17 1 64 4.0E-15 T 23-10-2018 IPR001210 Ribosomal protein S17e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_1230 c9fb56eab8f6464c3de435c450798588 67 Hamap MF_00511 30S ribosomal protein S17e [rps17e]. 1 63 22.153 T 23-10-2018 IPR001210 Ribosomal protein S17e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_1230 c9fb56eab8f6464c3de435c450798588 67 ProSitePatterns PS00712 Ribosomal protein S17e signature. 41 56 - T 23-10-2018 IPR018273 Ribosomal protein S17e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_1230 c9fb56eab8f6464c3de435c450798588 67 SUPERFAMILY SSF116820 1 60 1.7E-23 T 23-10-2018 IPR036401 Ribosomal protein S17e-like superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_1230 c9fb56eab8f6464c3de435c450798588 67 Gene3D G3DSA:1.10.60.20 1 62 8.0E-30 T 23-10-2018 IPR036401 Ribosomal protein S17e-like superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_1705 1377b42adecbd3eeb0bf86468d26cb7e 476 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 17 423 5.3E-61 T 23-10-2018 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 TON_1705 1377b42adecbd3eeb0bf86468d26cb7e 476 Gene3D G3DSA:3.40.720.10 4 304 3.4E-49 T 23-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 TON_1705 1377b42adecbd3eeb0bf86468d26cb7e 476 SUPERFAMILY SSF53649 15 462 1.4E-36 T 23-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 TON_1649 e3f916e67ae09992a6808fd2115adf63 126 Pfam PF04322 Protein of unknown function (DUF473) 1 113 2.8E-32 T 23-10-2018 IPR007417 Protein of unknown function DUF473 TON_1649 e3f916e67ae09992a6808fd2115adf63 126 ProDom PD020987 PF0014 UNCHARACTERIZED AF1250 PH0127 MJ0105 MA4414 ARCHAEAL 1 103 2.0E-34 T 23-10-2018 IPR007417 Protein of unknown function DUF473 TON_0539 b2581707044c9ba13f8ad183a7ed95f3 680 Pfam PF01568 Molydopterin dinucleotide binding domain 568 670 2.1E-29 T 23-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 TON_0539 b2581707044c9ba13f8ad183a7ed95f3 680 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 8 53 5.1E-9 T 23-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_0539 b2581707044c9ba13f8ad183a7ed95f3 680 SUPERFAMILY SSF53706 5 570 1.57E-222 T 23-10-2018 TON_0539 b2581707044c9ba13f8ad183a7ed95f3 680 TIGRFAM TIGR01591 Fdh-alpha: formate dehydrogenase, alpha subunit 8 674 4.5E-283 T 23-10-2018 IPR006478 Formate dehydrogenase, alpha subunit GO:0008863|GO:0015942|GO:0055114 KEGG: 00630+1.17.1.9|KEGG: 00680+1.17.1.9|MetaCyc: PWY-1881|MetaCyc: PWY-5497|MetaCyc: PWY-6696|MetaCyc: PWY-7985 TON_0539 b2581707044c9ba13f8ad183a7ed95f3 680 Gene3D G3DSA:2.20.25.90 2 57 1.5E-11 T 23-10-2018 TON_0539 b2581707044c9ba13f8ad183a7ed95f3 680 SUPERFAMILY SSF50692 529 676 6.5E-48 T 23-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily TON_0539 b2581707044c9ba13f8ad183a7ed95f3 680 Gene3D G3DSA:3.40.228.10 135 333 7.6E-199 T 23-10-2018 TON_0539 b2581707044c9ba13f8ad183a7ed95f3 680 Gene3D G3DSA:3.40.50.740 63 525 7.6E-199 T 23-10-2018 TON_0539 b2581707044c9ba13f8ad183a7ed95f3 680 Gene3D G3DSA:2.40.40.20 555 679 1.4E-41 T 23-10-2018 TON_0539 b2581707044c9ba13f8ad183a7ed95f3 680 Pfam PF00384 Molybdopterin oxidoreductase 58 480 2.5E-105 T 23-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_0539 b2581707044c9ba13f8ad183a7ed95f3 680 SMART SM00926 2 55 1.8E-10 T 23-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_0136 7b891229f8044e033183ab838b336fc3 440 Gene3D G3DSA:3.60.15.10 3 439 2.0E-135 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TON_0136 7b891229f8044e033183ab838b336fc3 440 Pfam PF00753 Metallo-beta-lactamase superfamily 13 183 2.9E-15 T 23-10-2018 IPR001279 Metallo-beta-lactamase TON_0136 7b891229f8044e033183ab838b336fc3 440 TIGRFAM TIGR00649 MG423: beta-CASP ribonuclease, RNase J family 2 440 1.4E-160 T 23-10-2018 IPR004613 Ribonuclease J GO:0003723|GO:0046872 TON_0136 7b891229f8044e033183ab838b336fc3 440 Gene3D G3DSA:3.40.50.10710 215 374 2.0E-135 T 23-10-2018 TON_0136 7b891229f8044e033183ab838b336fc3 440 ProSitePatterns PS01292 Uncharacterized protein family UPF0036 signature. 378 406 - T 23-10-2018 IPR001587 Ribonuclease J, conserved site TON_0136 7b891229f8044e033183ab838b336fc3 440 SUPERFAMILY SSF56281 2 439 1.31E-67 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TON_0136 7b891229f8044e033183ab838b336fc3 440 Hamap MF_01492 Ribonuclease J [rnj]. 1 440 49.954 T 23-10-2018 IPR030879 Ribonuclease J, archaea GO:0003723|GO:0004534|GO:0090503 TON_0136 7b891229f8044e033183ab838b336fc3 440 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 371 421 6.3E-12 T 23-10-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain TON_0136 7b891229f8044e033183ab838b336fc3 440 SMART SM00849 14 221 5.1E-24 T 23-10-2018 IPR001279 Metallo-beta-lactamase TON_1704 30fea90344851b6fba0eac7be6903539 181 SUPERFAMILY SSF52540 6 177 7.99E-37 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_1704 30fea90344851b6fba0eac7be6903539 181 Gene3D G3DSA:3.40.50.300 6 181 2.3E-60 T 23-10-2018 TON_1704 30fea90344851b6fba0eac7be6903539 181 Hamap MF_00065 Adenylyl-sulfate kinase [cysC]. 8 178 37.035 T 23-10-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 TON_1704 30fea90344851b6fba0eac7be6903539 181 Pfam PF01583 Adenylylsulphate kinase 9 160 1.3E-60 T 23-10-2018 TON_1704 30fea90344851b6fba0eac7be6903539 181 TIGRFAM TIGR00455 apsK: adenylyl-sulfate kinase 6 172 9.7E-69 T 23-10-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 TON_1856 fed571ebeb1f409de6a96868dce9fa1f 222 Gene3D G3DSA:3.40.50.300 6 215 1.3E-27 T 23-10-2018 TON_1856 fed571ebeb1f409de6a96868dce9fa1f 222 Pfam PF02223 Thymidylate kinase 11 34 1.2E-4 T 23-10-2018 IPR039430 Thymidylate kinase-like domain KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210 TON_1856 fed571ebeb1f409de6a96868dce9fa1f 222 SUPERFAMILY SSF52540 3 214 7.64E-20 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_1856 fed571ebeb1f409de6a96868dce9fa1f 222 Hamap MF_00165 Thymidylate kinase [tmk]. 5 218 12.715 T 23-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 TON_0111 8dd7dbdc635ea5c14b85b44bfa6e414d 341 PRINTS PR00148 Enolase signature 92 108 1.7E-5 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TON_0111 8dd7dbdc635ea5c14b85b44bfa6e414d 341 PRINTS PR00148 Enolase signature 316 330 1.7E-5 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TON_0111 8dd7dbdc635ea5c14b85b44bfa6e414d 341 Gene3D G3DSA:3.30.390.10 1 111 3.6E-21 T 23-10-2018 IPR029017 Enolase-like, N-terminal TON_0111 8dd7dbdc635ea5c14b85b44bfa6e414d 341 Pfam PF03952 Enolase, N-terminal domain 38 119 7.4E-23 T 23-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TON_0111 8dd7dbdc635ea5c14b85b44bfa6e414d 341 SMART SM01192 124 340 5.8E-15 T 23-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TON_0111 8dd7dbdc635ea5c14b85b44bfa6e414d 341 SUPERFAMILY SSF51604 125 339 2.89E-31 T 23-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily TON_0111 8dd7dbdc635ea5c14b85b44bfa6e414d 341 Gene3D G3DSA:3.20.20.120 219 339 1.7E-13 T 23-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily TON_0111 8dd7dbdc635ea5c14b85b44bfa6e414d 341 Pfam PF00113 Enolase, C-terminal TIM barrel domain 246 334 1.4E-8 T 23-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TON_0111 8dd7dbdc635ea5c14b85b44bfa6e414d 341 SMART SM01193 4 119 1.4E-32 T 23-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TON_0111 8dd7dbdc635ea5c14b85b44bfa6e414d 341 SUPERFAMILY SSF54826 4 125 4.77E-30 T 23-10-2018 TON_0071 42fcc43eabacc3dc49829e84f40f0b0f 156 Hamap MF_01331_A 50S ribosomal protein L22 [rplV]. 4 154 33.81 T 23-10-2018 IPR005721 Ribosomal protein L22/L17, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0071 42fcc43eabacc3dc49829e84f40f0b0f 156 TIGRFAM TIGR01038 uL22_arch_euk: ribosomal protein uL22 8 153 3.4E-67 T 23-10-2018 IPR005721 Ribosomal protein L22/L17, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0071 42fcc43eabacc3dc49829e84f40f0b0f 156 Pfam PF00237 Ribosomal protein L22p/L17e 21 151 3.0E-35 T 23-10-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 TON_0071 42fcc43eabacc3dc49829e84f40f0b0f 156 Gene3D G3DSA:3.90.470.10 6 156 1.4E-53 T 23-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 TON_0071 42fcc43eabacc3dc49829e84f40f0b0f 156 ProSitePatterns PS00464 Ribosomal protein L22 signature. 127 151 - T 23-10-2018 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0071 42fcc43eabacc3dc49829e84f40f0b0f 156 SUPERFAMILY SSF54843 8 153 2.22E-47 T 23-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 TON_0088 5b9364abb374c0ccd4bec5a7d698572e 148 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 1 148 14.184 T 23-10-2018 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 TON_0088 5b9364abb374c0ccd4bec5a7d698572e 148 Gene3D G3DSA:3.100.10.10 63 148 3.6E-21 T 23-10-2018 TON_0088 5b9364abb374c0ccd4bec5a7d698572e 148 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 29 146 1.9E-18 T 23-10-2018 IPR021131 Ribosomal protein L18e/L15P TON_0088 5b9364abb374c0ccd4bec5a7d698572e 148 SUPERFAMILY SSF52080 5 147 4.97E-33 T 23-10-2018 IPR036227 Ribosomal L18e/L15P superfamily TON_0088 5b9364abb374c0ccd4bec5a7d698572e 148 Gene3D G3DSA:4.10.990.10 4 52 6.5E-10 T 23-10-2018 IPR027386 50S ribosomal protein L15, N-terminal TON_0088 5b9364abb374c0ccd4bec5a7d698572e 148 ProSitePatterns PS00475 Ribosomal protein L15 signature. 112 142 - T 23-10-2018 IPR001196 Ribosomal protein L15, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0216 baad382db1285dc8b5eb43d307bd0d79 82 ProDom PD005155 RNA POLYMERASE DNA-DIRECTED SUBUNIT NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION II H POLYPEPTIDE 37 79 2.0E-17 T 23-10-2018 IPR000783 RNA polymerase, subunit H/Rpb5 C-terminal GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 TON_0216 baad382db1285dc8b5eb43d307bd0d79 82 Pfam PF01191 RNA polymerase Rpb5, C-terminal domain 7 79 5.2E-32 T 23-10-2018 IPR000783 RNA polymerase, subunit H/Rpb5 C-terminal GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 TON_0216 baad382db1285dc8b5eb43d307bd0d79 82 Gene3D G3DSA:3.90.940.20 1 82 1.1E-36 T 23-10-2018 IPR035913 RPB5-like RNA polymerase subunit superfamily Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 TON_0216 baad382db1285dc8b5eb43d307bd0d79 82 Hamap MF_00025 DNA-directed RNA polymerase subunit H [rpoH]. 7 80 23.822 T 23-10-2018 IPR020609 Archaeal RpoH /eukaryotic RPB5 RNA polymerase subunit GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 TON_0216 baad382db1285dc8b5eb43d307bd0d79 82 ProSitePatterns PS01110 RNA polymerases H / 23 Kd subunits signature. 12 25 - T 23-10-2018 IPR020608 RNA polymerase, subunit H/Rpb5, conserved site Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 TON_0216 baad382db1285dc8b5eb43d307bd0d79 82 SUPERFAMILY SSF55287 7 80 3.01E-28 T 23-10-2018 IPR035913 RPB5-like RNA polymerase subunit superfamily Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 TON_0688 f51d60bc35ee3db5fb6fa24e5a873ad2 335 TIGRFAM TIGR00303 TIGR00303: TIGR00303 family protein 3 322 4.4E-100 T 23-10-2018 IPR002805 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, putative TON_0688 f51d60bc35ee3db5fb6fa24e5a873ad2 335 Gene3D G3DSA:3.40.50.10210 1 333 5.2E-127 T 23-10-2018 TON_0688 f51d60bc35ee3db5fb6fa24e5a873ad2 335 Pfam PF02277 Phosphoribosyltransferase 100 250 3.7E-7 T 23-10-2018 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 TON_0688 f51d60bc35ee3db5fb6fa24e5a873ad2 335 SUPERFAMILY SSF52733 18 327 4.58E-44 T 23-10-2018 IPR036087 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like superfamily GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 TON_0688 f51d60bc35ee3db5fb6fa24e5a873ad2 335 Hamap MF_01086 UPF0284 protein . 1 335 138.813 T 23-10-2018 IPR002805 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, putative TON_1796 5ebd349ecd9e606d24d2c791af5f40f8 652 Pfam PF16561 Glycogen recognition site of AMP-activated protein kinase 20 81 3.4E-7 T 23-10-2018 IPR032640 AMP-activated protein kinase, glycogen-binding domain Reactome: R-HSA-1445148|Reactome: R-HSA-1632852|Reactome: R-HSA-2151209|Reactome: R-HSA-380972|Reactome: R-HSA-5628897|Reactome: R-HSA-6804756 TON_1796 5ebd349ecd9e606d24d2c791af5f40f8 652 SMART SM00642 208 577 6.1E-93 T 23-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 TON_1796 5ebd349ecd9e606d24d2c791af5f40f8 652 SUPERFAMILY SSF81296 23 81 1.62E-11 T 23-10-2018 IPR014756 Immunoglobulin E-set TON_1796 5ebd349ecd9e606d24d2c791af5f40f8 652 SUPERFAMILY SSF51445 196 586 1.34E-96 T 23-10-2018 IPR017853 Glycoside hydrolase superfamily TON_1796 5ebd349ecd9e606d24d2c791af5f40f8 652 SUPERFAMILY SSF81296 107 203 6.3E-13 T 23-10-2018 IPR014756 Immunoglobulin E-set TON_1796 5ebd349ecd9e606d24d2c791af5f40f8 652 SUPERFAMILY SSF51011 586 648 1.26E-5 T 23-10-2018 TON_1796 5ebd349ecd9e606d24d2c791af5f40f8 652 Pfam PF02903 Alpha amylase, N-terminal ig-like domain 109 189 5.7E-10 T 23-10-2018 IPR004185 Glycoside hydrolase, family 13, N-terminal Ig-like domain GO:0004553|GO:0005975 TON_1796 5ebd349ecd9e606d24d2c791af5f40f8 652 Gene3D G3DSA:2.60.40.10 1 103 4.9E-21 T 23-10-2018 IPR013783 Immunoglobulin-like fold TON_1796 5ebd349ecd9e606d24d2c791af5f40f8 652 Gene3D G3DSA:2.60.40.1180 583 647 7.0E-5 T 23-10-2018 IPR013780 Glycosyl hydrolase, all-beta TON_1796 5ebd349ecd9e606d24d2c791af5f40f8 652 Pfam PF00128 Alpha amylase, catalytic domain 236 542 5.3E-64 T 23-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 TON_1796 5ebd349ecd9e606d24d2c791af5f40f8 652 Gene3D G3DSA:2.60.40.10 104 195 1.1E-29 T 23-10-2018 IPR013783 Immunoglobulin-like fold TON_1796 5ebd349ecd9e606d24d2c791af5f40f8 652 Gene3D G3DSA:3.20.20.80 196 582 3.3E-147 T 23-10-2018 TON_0112 cd3072bdce7e89f1b5b50e1ea9c37d82 201 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 8 19 - T 23-10-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 TON_0112 cd3072bdce7e89f1b5b50e1ea9c37d82 201 SUPERFAMILY SSF52313 3 192 9.55E-62 T 23-10-2018 IPR023591 Ribosomal protein S2, flavodoxin-like domain superfamily TON_0112 cd3072bdce7e89f1b5b50e1ea9c37d82 201 Hamap MF_00291_A 30S ribosomal protein S2 [rpsB]. 1 198 48.329 T 23-10-2018 IPR023454 Ribosomal protein S2, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 TON_0112 cd3072bdce7e89f1b5b50e1ea9c37d82 201 TIGRFAM TIGR01012 uS2_euk_arch: ribosomal protein uS2 3 197 3.1E-99 T 23-10-2018 IPR005707 Ribosomal protein S2, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0112 cd3072bdce7e89f1b5b50e1ea9c37d82 201 ProSitePatterns PS00963 Ribosomal protein S2 signature 2. 111 135 - T 23-10-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 TON_0112 cd3072bdce7e89f1b5b50e1ea9c37d82 201 Pfam PF00318 Ribosomal protein S2 110 174 2.4E-13 T 23-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TON_0112 cd3072bdce7e89f1b5b50e1ea9c37d82 201 Pfam PF00318 Ribosomal protein S2 12 103 9.1E-11 T 23-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TON_0112 cd3072bdce7e89f1b5b50e1ea9c37d82 201 PRINTS PR00395 Ribosomal protein S2 signature 86 103 6.3E-31 T 23-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TON_0112 cd3072bdce7e89f1b5b50e1ea9c37d82 201 PRINTS PR00395 Ribosomal protein S2 signature 111 128 6.3E-31 T 23-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TON_0112 cd3072bdce7e89f1b5b50e1ea9c37d82 201 PRINTS PR00395 Ribosomal protein S2 signature 8 26 6.3E-31 T 23-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TON_0112 cd3072bdce7e89f1b5b50e1ea9c37d82 201 PRINTS PR00395 Ribosomal protein S2 signature 149 163 6.3E-31 T 23-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TON_0112 cd3072bdce7e89f1b5b50e1ea9c37d82 201 PRINTS PR00395 Ribosomal protein S2 signature 128 139 6.3E-31 T 23-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TON_0112 cd3072bdce7e89f1b5b50e1ea9c37d82 201 PRINTS PR00395 Ribosomal protein S2 signature 38 47 6.3E-31 T 23-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TON_0112 cd3072bdce7e89f1b5b50e1ea9c37d82 201 Gene3D G3DSA:3.40.50.10490 7 201 4.7E-71 T 23-10-2018 TON_0320 81d9868203be828a1a89533c4b5c46e5 85 TIGRFAM TIGR01573 cas2: CRISPR-associated endonuclease Cas2 1 78 7.6E-13 T 23-10-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 TON_0320 81d9868203be828a1a89533c4b5c46e5 85 Gene3D G3DSA:3.30.70.240 1 66 4.2E-31 T 23-10-2018 TON_0320 81d9868203be828a1a89533c4b5c46e5 85 Pfam PF09827 CRISPR associated protein Cas2 1 70 1.2E-21 T 23-10-2018 IPR019199 Virulence-associated protein D / CRISPR associated protein Cas2 TON_0320 81d9868203be828a1a89533c4b5c46e5 85 Hamap MF_01471 CRISPR-associated endoribonuclease Cas2 [cas2]. 1 85 16.312 T 23-10-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 TON_0320 81d9868203be828a1a89533c4b5c46e5 85 SUPERFAMILY SSF143430 1 80 3.53E-25 T 23-10-2018 TON_0699 fdca5a5c6f388995fccf0ce802e02b93 427 Pfam PF01336 OB-fold nucleic acid binding domain 270 341 2.1E-8 T 23-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 TON_0699 fdca5a5c6f388995fccf0ce802e02b93 427 Hamap MF_01892 tRNA(Ile2) 2-agmatinylcytidine synthetase TiaS [tiaS]. 3 422 36.849 T 23-10-2018 IPR024913 tRNA(Ile2) 2-agmatinylcytidine synthetase TiaS GO:0002101|GO:0016879 TON_0699 fdca5a5c6f388995fccf0ce802e02b93 427 Pfam PF08489 Domain of unknown function (DUF1743) 140 253 1.6E-38 T 23-10-2018 IPR013696 Domain of unknown function DUF1743 TON_0699 fdca5a5c6f388995fccf0ce802e02b93 427 Gene3D G3DSA:2.40.50.1010 252 401 3.1E-43 T 23-10-2018 TON_0699 fdca5a5c6f388995fccf0ce802e02b93 427 SUPERFAMILY SSF50249 254 347 9.95E-5 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold TON_0699 fdca5a5c6f388995fccf0ce802e02b93 427 Gene3D G3DSA:3.30.70.2200 2 155 5.3E-62 T 23-10-2018 TON_0699 fdca5a5c6f388995fccf0ce802e02b93 427 Gene3D G3DSA:3.90.600.20 156 251 2.1E-35 T 23-10-2018 TON_0449 21897d1f2d5c55b950b078e4e2ee6efb 328 Pfam PF02272 DHHA1 domain 247 317 8.1E-12 T 23-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 TON_0449 21897d1f2d5c55b950b078e4e2ee6efb 328 Gene3D G3DSA:3.10.310.40 222 323 3.1E-6 T 23-10-2018 TON_0449 21897d1f2d5c55b950b078e4e2ee6efb 328 SUPERFAMILY SSF64182 17 306 1.7E-50 T 23-10-2018 IPR038763 DHH phosphoesterase superfamily TON_0449 21897d1f2d5c55b950b078e4e2ee6efb 328 Pfam PF01368 DHH family 19 159 5.9E-13 T 23-10-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 TON_0449 21897d1f2d5c55b950b078e4e2ee6efb 328 Gene3D G3DSA:3.90.1640.10 6 191 4.1E-38 T 23-10-2018 TON_0027 5a4418d3cc37b4104f9c97d58951fdb9 260 Pfam PF00227 Proteasome subunit 33 215 3.4E-64 T 23-10-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 TON_0027 5a4418d3cc37b4104f9c97d58951fdb9 260 Gene3D G3DSA:3.60.20.10 5 253 4.5E-91 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TON_0027 5a4418d3cc37b4104f9c97d58951fdb9 260 SUPERFAMILY SSF56235 7 242 7.53E-82 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TON_0027 5a4418d3cc37b4104f9c97d58951fdb9 260 Hamap MF_00289_A Proteasome subunit alpha [prcA]. 5 234 48.004 T 23-10-2018 IPR019982 Proteasome alpha subunit, archaeal GO:0004298|GO:0005839|GO:0051603 TON_0027 5a4418d3cc37b4104f9c97d58951fdb9 260 Pfam PF10584 Proteasome subunit A N-terminal signature 10 32 4.0E-12 T 23-10-2018 IPR000426 Proteasome alpha-subunit, N-terminal domain GO:0004175|GO:0006511|GO:0019773 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 TON_0027 5a4418d3cc37b4104f9c97d58951fdb9 260 SMART SM00948 10 32 3.4E-10 T 23-10-2018 IPR000426 Proteasome alpha-subunit, N-terminal domain GO:0004175|GO:0006511|GO:0019773 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 TON_0027 5a4418d3cc37b4104f9c97d58951fdb9 260 ProSitePatterns PS00388 Proteasome alpha-type subunits signature. 10 32 - T 23-10-2018 IPR000426 Proteasome alpha-subunit, N-terminal domain GO:0004175|GO:0006511|GO:0019773 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 TON_0027 5a4418d3cc37b4104f9c97d58951fdb9 260 TIGRFAM TIGR03633 arc_protsome_A: proteasome endopeptidase complex, archaeal, alpha subunit 8 234 3.9E-107 T 23-10-2018 IPR019982 Proteasome alpha subunit, archaeal GO:0004298|GO:0005839|GO:0051603 TON_0217 332a2f4ec200734b57b9f8295756cca5 1120 Gene3D G3DSA:2.40.50.150 681 872 6.0E-146 T 23-10-2018 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TON_0217 332a2f4ec200734b57b9f8295756cca5 1120 Pfam PF04561 RNA polymerase Rpb2, domain 2 173 346 5.5E-40 T 23-10-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TON_0217 332a2f4ec200734b57b9f8295756cca5 1120 Gene3D G3DSA:3.90.1100.10 19 174 1.0E-12 T 23-10-2018 TON_0217 332a2f4ec200734b57b9f8295756cca5 1120 TIGRFAM TIGR03670 rpoB_arch: DNA-directed RNA polymerase subunit B 519 1119 0.0 T 23-10-2018 IPR019969 DNA-directed RNA polymerase subunit B (Rpo2) GO:0003677|GO:0003899|GO:0006351|GO:0008270 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TON_0217 332a2f4ec200734b57b9f8295756cca5 1120 Gene3D G3DSA:3.90.1110.10 175 334 6.4E-59 T 23-10-2018 IPR037034 RNA polymerase Rpb2, domain 2 superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TON_0217 332a2f4ec200734b57b9f8295756cca5 1120 Pfam PF00562 RNA polymerase Rpb2, domain 6 651 1023 4.6E-133 T 23-10-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TON_0217 332a2f4ec200734b57b9f8295756cca5 1120 Pfam PF04565 RNA polymerase Rpb2, domain 3 422 486 1.6E-30 T 23-10-2018 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TON_0217 332a2f4ec200734b57b9f8295756cca5 1120 Gene3D G3DSA:3.90.1100.10 335 505 1.4E-55 T 23-10-2018 TON_0217 332a2f4ec200734b57b9f8295756cca5 1120 Pfam PF04560 RNA polymerase Rpb2, domain 7 1025 1114 3.7E-30 T 23-10-2018 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TON_0217 332a2f4ec200734b57b9f8295756cca5 1120 Gene3D G3DSA:2.40.270.10 651 1009 6.0E-146 T 23-10-2018 IPR037033 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TON_0217 332a2f4ec200734b57b9f8295756cca5 1120 SUPERFAMILY SSF64484 10 1114 0.0 T 23-10-2018 TON_0217 332a2f4ec200734b57b9f8295756cca5 1120 Gene3D G3DSA:3.90.1800.10 1010 1118 9.1E-41 T 23-10-2018 TON_0217 332a2f4ec200734b57b9f8295756cca5 1120 ProSitePatterns PS01166 RNA polymerases beta chain signature. 876 888 - T 23-10-2018 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TON_0217 332a2f4ec200734b57b9f8295756cca5 1120 Pfam PF04567 RNA polymerase Rpb2, domain 5 603 635 2.4E-8 T 23-10-2018 IPR007647 RNA polymerase Rpb2, domain 5 GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TON_0217 332a2f4ec200734b57b9f8295756cca5 1120 Pfam PF04563 RNA polymerase beta subunit 26 379 7.2E-55 T 23-10-2018 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TON_0217 332a2f4ec200734b57b9f8295756cca5 1120 Pfam PF04566 RNA polymerase Rpb2, domain 4 519 582 1.9E-19 T 23-10-2018 IPR007646 RNA polymerase Rpb2, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TON_1077 cd26108e1aa5773e227dcd3627b1a4b7 216 Pfam PF02811 PHP domain 5 103 1.9E-8 T 23-10-2018 IPR004013 PHP domain GO:0003824 TON_1077 cd26108e1aa5773e227dcd3627b1a4b7 216 Gene3D G3DSA:3.20.20.140 1 214 3.6E-50 T 23-10-2018 TON_1077 cd26108e1aa5773e227dcd3627b1a4b7 216 SMART SM00481 4 76 1.8E-14 T 23-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal TON_1077 cd26108e1aa5773e227dcd3627b1a4b7 216 SUPERFAMILY SSF89550 2 212 1.2E-40 T 23-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 TON_1568 e6d66175ec74cbf219e4dcd2cdc7ae5d 307 ProSitePatterns PS00668 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. 190 203 - T 23-10-2018 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_1568 e6d66175ec74cbf219e4dcd2cdc7ae5d 307 Pfam PF00146 NADH dehydrogenase 13 302 8.6E-44 T 23-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_0604 767ee6b8d3ab8654580ee584c8676ab2 200 Pfam PF02517 CAAX protease self-immunity 111 188 2.0E-10 T 23-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 TON_0039 9919cf2d6364f9d36e04ccc40b605c92 154 SUPERFAMILY SSF51230 79 153 2.22E-26 T 23-10-2018 IPR011053 Single hybrid motif TON_0039 9919cf2d6364f9d36e04ccc40b605c92 154 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 110 127 - T 23-10-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 TON_0039 9919cf2d6364f9d36e04ccc40b605c92 154 Gene3D G3DSA:2.40.50.100 81 154 5.7E-30 T 23-10-2018 TON_0039 9919cf2d6364f9d36e04ccc40b605c92 154 Pfam PF00364 Biotin-requiring enzyme 88 153 6.0E-26 T 23-10-2018 IPR000089 Biotin/lipoyl attachment TON_1461 5d6acae48e387056a4bc8b4c12a75e5a 425 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 236 403 4.3E-31 T 23-10-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824 Reactome: R-HSA-196843 TON_1461 5d6acae48e387056a4bc8b4c12a75e5a 425 Gene3D G3DSA:3.40.50.620 182 400 1.3E-32 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TON_1461 5d6acae48e387056a4bc8b4c12a75e5a 425 SUPERFAMILY SSF52402 225 392 5.07E-31 T 23-10-2018 TON_0824 02ac6ef3d6a3b0749b3d5b15546411e4 110 ProSitePatterns PS01030 RNA polymerases M / 15 Kd subunits signature. 3 25 - T 23-10-2018 IPR019761 DNA-directed RNA polymerase M, 15kDa subunit, conserved site TON_0824 02ac6ef3d6a3b0749b3d5b15546411e4 110 Gene3D G3DSA:2.20.25.10 55 110 8.2E-28 T 23-10-2018 TON_0824 02ac6ef3d6a3b0749b3d5b15546411e4 110 PIRSF PIRSF005586 1 110 2.5E-39 T 23-10-2018 IPR012164 DNA-directed RNA polymerase subunit/transcription factor S GO:0006351 TON_0824 02ac6ef3d6a3b0749b3d5b15546411e4 110 Pfam PF01096 Transcription factor S-II (TFIIS) 69 107 1.5E-22 T 23-10-2018 IPR001222 Zinc finger, TFIIS-type GO:0003676|GO:0006351|GO:0008270 TON_0824 02ac6ef3d6a3b0749b3d5b15546411e4 110 SMART SM00661 2 56 7.2E-15 T 23-10-2018 IPR001529 DNA-directed RNA polymerase, M/15kDa subunit GO:0006351 TON_0824 02ac6ef3d6a3b0749b3d5b15546411e4 110 Gene3D G3DSA:2.20.25.10 1 35 3.2E-5 T 23-10-2018 TON_0824 02ac6ef3d6a3b0749b3d5b15546411e4 110 TIGRFAM TIGR01384 TFS_arch: transcription factor S 2 110 1.5E-38 T 23-10-2018 IPR006288 Transcription factor S GO:0006355 TON_0824 02ac6ef3d6a3b0749b3d5b15546411e4 110 SUPERFAMILY SSF57783 1 34 6.8E-7 T 23-10-2018 TON_0824 02ac6ef3d6a3b0749b3d5b15546411e4 110 Pfam PF02150 RNA polymerases M/15 Kd subunit 1 34 4.3E-16 T 23-10-2018 IPR001529 DNA-directed RNA polymerase, M/15kDa subunit GO:0006351 TON_0824 02ac6ef3d6a3b0749b3d5b15546411e4 110 ProSitePatterns PS00466 Zinc finger TFIIS-type signature. 71 106 - T 23-10-2018 IPR001222 Zinc finger, TFIIS-type GO:0003676|GO:0006351|GO:0008270 TON_0824 02ac6ef3d6a3b0749b3d5b15546411e4 110 SMART SM00440 69 108 2.5E-25 T 23-10-2018 IPR001222 Zinc finger, TFIIS-type GO:0003676|GO:0006351|GO:0008270 TON_0824 02ac6ef3d6a3b0749b3d5b15546411e4 110 SUPERFAMILY SSF57783 48 109 2.78E-24 T 23-10-2018 TON_1515 4576c9bee8dfc9715c5d9d55d7529f3c 562 Pfam PF04675 DNA ligase N terminus 6 179 4.8E-37 T 23-10-2018 IPR012308 DNA ligase, ATP-dependent, N-terminal GO:0003677|GO:0003910|GO:0006281|GO:0006310 TON_1515 4576c9bee8dfc9715c5d9d55d7529f3c 562 ProSitePatterns PS00333 ATP-dependent DNA ligase signature 2. 401 425 - T 23-10-2018 IPR016059 DNA ligase, ATP-dependent, conserved site GO:0003909|GO:0051103 TON_1515 4576c9bee8dfc9715c5d9d55d7529f3c 562 SUPERFAMILY SSF117018 3 244 4.45E-69 T 23-10-2018 IPR036599 DNA ligase, ATP-dependent, N-terminal domain superfamily GO:0003677|GO:0003910|GO:0006281|GO:0006310 TON_1515 4576c9bee8dfc9715c5d9d55d7529f3c 562 Pfam PF04679 ATP dependent DNA ligase C terminal region 446 537 4.3E-20 T 23-10-2018 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 TON_1515 4576c9bee8dfc9715c5d9d55d7529f3c 562 Gene3D G3DSA:3.30.470.30 224 425 3.5E-75 T 23-10-2018 TON_1515 4576c9bee8dfc9715c5d9d55d7529f3c 562 TIGRFAM TIGR00574 dnl1: DNA ligase I, ATP-dependent (dnl1) 60 553 7.5E-164 T 23-10-2018 IPR000977 DNA ligase, ATP-dependent GO:0003910|GO:0005524|GO:0006281|GO:0006310|GO:0071897 TON_1515 4576c9bee8dfc9715c5d9d55d7529f3c 562 Hamap MF_00407 DNA ligase [lig]. 4 553 34.435 T 23-10-2018 IPR022865 DNA ligase, ATP-dependent, bacterial/archaeal GO:0003910 TON_1515 4576c9bee8dfc9715c5d9d55d7529f3c 562 SUPERFAMILY SSF56091 222 425 1.56E-55 T 23-10-2018 TON_1515 4576c9bee8dfc9715c5d9d55d7529f3c 562 SUPERFAMILY SSF50249 428 555 1.03E-40 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold TON_1515 4576c9bee8dfc9715c5d9d55d7529f3c 562 Gene3D G3DSA:2.40.50.140 426 562 1.1E-51 T 23-10-2018 TON_1515 4576c9bee8dfc9715c5d9d55d7529f3c 562 ProSitePatterns PS00697 ATP-dependent DNA ligase AMP-binding site. 250 258 - T 23-10-2018 IPR016059 DNA ligase, ATP-dependent, conserved site GO:0003909|GO:0051103 TON_1515 4576c9bee8dfc9715c5d9d55d7529f3c 562 Pfam PF01068 ATP dependent DNA ligase domain 227 425 1.5E-65 T 23-10-2018 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 TON_1515 4576c9bee8dfc9715c5d9d55d7529f3c 562 Gene3D G3DSA:1.10.3260.10 1 223 1.6E-83 T 23-10-2018 IPR036599 DNA ligase, ATP-dependent, N-terminal domain superfamily GO:0003677|GO:0003910|GO:0006281|GO:0006310 TON_0873 d06b0b76c39ee5d880fbcf6d75161dab 159 Gene3D G3DSA:1.20.1260.10 1 143 6.0E-26 T 23-10-2018 IPR012347 Ferritin-like TON_0873 d06b0b76c39ee5d880fbcf6d75161dab 159 SUPERFAMILY SSF47240 1 147 7.37E-29 T 23-10-2018 IPR009078 Ferritin-like superfamily TON_0873 d06b0b76c39ee5d880fbcf6d75161dab 159 Pfam PF02915 Rubrerythrin 5 138 5.7E-17 T 23-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 TON_1426 a471502fd0567f8b58cb988973a6fe90 200 Gene3D G3DSA:3.60.20.10 1 198 6.3E-63 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TON_1426 a471502fd0567f8b58cb988973a6fe90 200 TIGRFAM TIGR03634 arc_protsome_B: proteasome endopeptidase complex, archaeal, beta subunit 7 190 5.6E-78 T 23-10-2018 IPR019983 Peptidase T1A, proteasome beta-subunit, archaeal GO:0004175|GO:0005839|GO:0051603 TON_1426 a471502fd0567f8b58cb988973a6fe90 200 PRINTS PR00141 Proteasome component signature 146 157 1.5E-7 T 23-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 TON_1426 a471502fd0567f8b58cb988973a6fe90 200 PRINTS PR00141 Proteasome component signature 135 146 1.5E-7 T 23-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 TON_1426 a471502fd0567f8b58cb988973a6fe90 200 PRINTS PR00141 Proteasome component signature 15 30 1.5E-7 T 23-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 TON_1426 a471502fd0567f8b58cb988973a6fe90 200 Hamap MF_02113_A Proteasome subunit beta [prcB]. 3 199 34.882 T 23-10-2018 IPR019983 Peptidase T1A, proteasome beta-subunit, archaeal GO:0004175|GO:0005839|GO:0051603 TON_1426 a471502fd0567f8b58cb988973a6fe90 200 ProSitePatterns PS00854 Proteasome beta-type subunits signature. 11 58 - T 23-10-2018 IPR016050 Proteasome beta-type subunit, conserved site GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 TON_1426 a471502fd0567f8b58cb988973a6fe90 200 Pfam PF00227 Proteasome subunit 5 179 1.1E-52 T 23-10-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 TON_1426 a471502fd0567f8b58cb988973a6fe90 200 SUPERFAMILY SSF56235 2 193 1.38E-59 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TON_0911 5461920b3b6284d52c538848c5fe968a 339 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 339 98.353 T 23-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 TON_0911 5461920b3b6284d52c538848c5fe968a 339 SUPERFAMILY SSF52540 1 335 2.66E-108 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_0911 5461920b3b6284d52c538848c5fe968a 339 Gene3D G3DSA:3.40.440.10 1 339 2.4E-137 T 23-10-2018 TON_0911 5461920b3b6284d52c538848c5fe968a 339 SMART SM00788 3 334 2.7E-158 T 23-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 TON_0911 5461920b3b6284d52c538848c5fe968a 339 Pfam PF00709 Adenylosuccinate synthetase 149 289 1.3E-44 T 23-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 TON_0911 5461920b3b6284d52c538848c5fe968a 339 Pfam PF00709 Adenylosuccinate synthetase 294 333 2.2E-5 T 23-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 TON_0911 5461920b3b6284d52c538848c5fe968a 339 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 10 17 - T 23-10-2018 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 TON_0908 10b57af18395036eaba9fc8777e48cba 97 Pfam PF01883 Iron-sulfur cluster assembly protein 6 58 4.2E-8 T 23-10-2018 IPR002744 MIP18 family-like TON_0908 10b57af18395036eaba9fc8777e48cba 97 SUPERFAMILY SSF117916 4 66 1.08E-7 T 23-10-2018 IPR034904 Fe-S cluster assembly domain superfamily TON_0908 10b57af18395036eaba9fc8777e48cba 97 Gene3D G3DSA:3.30.300.130 3 86 4.4E-6 T 23-10-2018 IPR034904 Fe-S cluster assembly domain superfamily TON_0840 aa28cf77b889f670ca08fa9b3c898443 642 Gene3D G3DSA:3.40.1110.10 346 464 5.7E-98 T 23-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 TON_0840 aa28cf77b889f670ca08fa9b3c898443 642 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 74 639 1.1E-192 T 23-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 TON_0840 aa28cf77b889f670ca08fa9b3c898443 642 SUPERFAMILY SSF81665 73 612 5.49E-14 T 23-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 TON_0840 aa28cf77b889f670ca08fa9b3c898443 642 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 532 551 3.8E-29 T 23-10-2018 TON_0840 aa28cf77b889f670ca08fa9b3c898443 642 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 479 489 3.8E-29 T 23-10-2018 TON_0840 aa28cf77b889f670ca08fa9b3c898443 642 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 185 199 3.8E-29 T 23-10-2018 TON_0840 aa28cf77b889f670ca08fa9b3c898443 642 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 555 567 3.8E-29 T 23-10-2018 TON_0840 aa28cf77b889f670ca08fa9b3c898443 642 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 335 349 3.8E-29 T 23-10-2018 TON_0840 aa28cf77b889f670ca08fa9b3c898443 642 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 457 468 3.8E-29 T 23-10-2018 TON_0840 aa28cf77b889f670ca08fa9b3c898443 642 Pfam PF00122 E1-E2 ATPase 135 315 1.1E-52 T 23-10-2018 TON_0840 aa28cf77b889f670ca08fa9b3c898443 642 Gene3D G3DSA:3.40.50.1000 329 582 5.7E-98 T 23-10-2018 IPR023214 HAD superfamily TON_0840 aa28cf77b889f670ca08fa9b3c898443 642 SUPERFAMILY SSF56784 333 637 1.19E-60 T 23-10-2018 IPR036412 HAD-like superfamily TON_0840 aa28cf77b889f670ca08fa9b3c898443 642 Gene3D G3DSA:2.70.150.20 123 239 2.7E-39 T 23-10-2018 TON_0840 aa28cf77b889f670ca08fa9b3c898443 642 SUPERFAMILY SSF81653 138 235 7.06E-28 T 23-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 TON_0840 aa28cf77b889f670ca08fa9b3c898443 642 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 56 641 1.1E-194 T 23-10-2018 TON_0840 aa28cf77b889f670ca08fa9b3c898443 642 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 111 613 2.3E-95 T 23-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 TON_0840 aa28cf77b889f670ca08fa9b3c898443 642 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 337 343 - T 23-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 TON_0840 aa28cf77b889f670ca08fa9b3c898443 642 Pfam PF00702 haloacid dehalogenase-like hydrolase 332 546 5.4E-43 T 23-10-2018 TON_0840 aa28cf77b889f670ca08fa9b3c898443 642 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 563 588 7.1E-11 T 23-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 TON_0840 aa28cf77b889f670ca08fa9b3c898443 642 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 504 520 7.1E-11 T 23-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 TON_0840 aa28cf77b889f670ca08fa9b3c898443 642 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 532 548 7.1E-11 T 23-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 TON_0672 bf973378177c36168d55ac39710cbf30 441 Gene3D G3DSA:3.30.2290.10 1 206 3.1E-19 T 23-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal TON_0672 bf973378177c36168d55ac39710cbf30 441 Pfam PF01523 Putative modulator of DNA gyrase 15 304 1.7E-46 T 23-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 TON_0672 bf973378177c36168d55ac39710cbf30 441 SUPERFAMILY SSF111283 2 439 1.96E-95 T 23-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 TON_0369 9005cb403ef7790f75e5d4273eed5dd9 345 PIRSF PIRSF001123 1 344 1.0E-100 T 23-10-2018 IPR008007 Peptidase M42 TON_0369 9005cb403ef7790f75e5d4273eed5dd9 345 Gene3D G3DSA:2.40.30.40 68 160 6.4E-132 T 23-10-2018 IPR023367 Peptidase M42, domain 2 TON_0369 9005cb403ef7790f75e5d4273eed5dd9 345 Pfam PF05343 M42 glutamyl aminopeptidase 45 330 2.5E-96 T 23-10-2018 IPR008007 Peptidase M42 TON_0369 9005cb403ef7790f75e5d4273eed5dd9 345 SUPERFAMILY SSF101821 68 176 1.1E-26 T 23-10-2018 TON_0369 9005cb403ef7790f75e5d4273eed5dd9 345 SUPERFAMILY SSF53187 4 338 1.81E-61 T 23-10-2018 TON_0369 9005cb403ef7790f75e5d4273eed5dd9 345 Gene3D G3DSA:3.40.630.10 7 332 6.4E-132 T 23-10-2018 TON_1396 ee9de2e1cc351bae4c8df9c766718126 228 SUPERFAMILY SSF53335 13 220 3.35E-37 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TON_1396 ee9de2e1cc351bae4c8df9c766718126 228 Pfam PF13649 Methyltransferase domain 42 136 7.5E-25 T 23-10-2018 TON_1396 ee9de2e1cc351bae4c8df9c766718126 228 Gene3D G3DSA:3.40.50.150 1 227 8.4E-68 T 23-10-2018 TON_0061 6e84865831d81ee03b3fc5710eadb94f 384 SUPERFAMILY SSF53383 22 382 1.05E-94 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TON_0061 6e84865831d81ee03b3fc5710eadb94f 384 PIRSF PIRSF000524 17 384 2.1E-99 T 23-10-2018 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832|Reactome: R-HSA-389661|Reactome: R-HSA-9033241 TON_0061 6e84865831d81ee03b3fc5710eadb94f 384 Pfam PF00266 Aminotransferase class-V 45 369 2.4E-39 T 23-10-2018 IPR000192 Aminotransferase class V domain TON_0061 6e84865831d81ee03b3fc5710eadb94f 384 Gene3D G3DSA:3.40.640.10 35 280 7.9E-135 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TON_0061 6e84865831d81ee03b3fc5710eadb94f 384 Gene3D G3DSA:3.90.1150.10 25 378 7.9E-135 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TON_0061 6e84865831d81ee03b3fc5710eadb94f 384 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 202 222 - T 23-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site TON_1072 e8c3ee4b435f138ef0619c69a088c9e8 1188 ProDom PD936484 POLYPROTEIN GLYCOPROTEIN M G2 TRANSMEMBRANE NONSTRUCTURAL MEMBRANE CONTAINS: PRECURSOR SIGNAL 194 453 0.006 T 23-10-2018 TON_1072 e8c3ee4b435f138ef0619c69a088c9e8 1188 Gene3D G3DSA:3.40.50.300 1010 1181 2.8E-59 T 23-10-2018 TON_1072 e8c3ee4b435f138ef0619c69a088c9e8 1188 TIGRFAM TIGR02169 SMC_prok_A: chromosome segregation protein SMC 3 1161 0.0 T 23-10-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 TON_1072 e8c3ee4b435f138ef0619c69a088c9e8 1188 TIGRFAM TIGR02168 SMC_prok_B: chromosome segregation protein SMC 3 1161 2.8E-233 T 23-10-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 TON_1072 e8c3ee4b435f138ef0619c69a088c9e8 1188 SUPERFAMILY SSF57997 379 512 1.14E-6 T 23-10-2018 TON_1072 e8c3ee4b435f138ef0619c69a088c9e8 1188 SUPERFAMILY SSF57997 714 964 4.32E-8 T 23-10-2018 TON_1072 e8c3ee4b435f138ef0619c69a088c9e8 1188 Gene3D G3DSA:1.20.1060.20 506 663 1.8E-45 T 23-10-2018 TON_1072 e8c3ee4b435f138ef0619c69a088c9e8 1188 Gene3D G3DSA:3.40.50.300 2 233 1.1E-60 T 23-10-2018 TON_1072 e8c3ee4b435f138ef0619c69a088c9e8 1188 Gene3D G3DSA:1.20.5.340 780 872 2.3E-7 T 23-10-2018 TON_1072 e8c3ee4b435f138ef0619c69a088c9e8 1188 Hamap MF_01894 Chromosome partition protein Smc [smc]. 2 1163 21.299 T 23-10-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 TON_1072 e8c3ee4b435f138ef0619c69a088c9e8 1188 Pfam PF06470 SMC proteins Flexible Hinge Domain 520 631 1.8E-32 T 23-10-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 TON_1072 e8c3ee4b435f138ef0619c69a088c9e8 1188 Pfam PF02463 RecF/RecN/SMC N terminal domain 3 1154 2.8E-71 T 23-10-2018 IPR003395 RecF/RecN/SMC, N-terminal TON_1072 e8c3ee4b435f138ef0619c69a088c9e8 1188 PIRSF PIRSF005719 1 1168 1.1E-281 T 23-10-2018 IPR024704 Structural maintenance of chromosomes protein TON_1072 e8c3ee4b435f138ef0619c69a088c9e8 1188 SMART SM00968 520 632 6.4E-42 T 23-10-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 TON_1072 e8c3ee4b435f138ef0619c69a088c9e8 1188 SUPERFAMILY SSF75553 481 675 1.7E-50 T 23-10-2018 IPR036277 SMCs flexible hinge superfamily GO:0005515|GO:0005524|GO:0005694|GO:0051276 TON_1072 e8c3ee4b435f138ef0619c69a088c9e8 1188 SUPERFAMILY SSF52540 1 1168 3.32E-55 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_1072 e8c3ee4b435f138ef0619c69a088c9e8 1188 Gene3D G3DSA:3.30.70.1620 581 658 1.8E-45 T 23-10-2018 TON_1611 1cd44ddfb8b9f58d4344979940bc528b 405 Gene3D G3DSA:1.20.1250.20 6 381 3.7E-32 T 23-10-2018 TON_1611 1cd44ddfb8b9f58d4344979940bc528b 405 SUPERFAMILY SSF103473 11 380 4.58E-32 T 23-10-2018 IPR036259 MFS transporter superfamily TON_1611 1cd44ddfb8b9f58d4344979940bc528b 405 Pfam PF07690 Major Facilitator Superfamily 9 348 8.8E-17 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TON_1661 880b6174c93ffe45dc6885b0dda19d2b 185 Gene3D G3DSA:1.10.10.10 1 85 3.9E-21 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TON_1661 880b6174c93ffe45dc6885b0dda19d2b 185 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 13 28 4.1E-5 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TON_1661 880b6174c93ffe45dc6885b0dda19d2b 185 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 45 60 4.1E-5 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TON_1661 880b6174c93ffe45dc6885b0dda19d2b 185 SUPERFAMILY SSF46785 9 124 9.1E-23 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TON_1661 880b6174c93ffe45dc6885b0dda19d2b 185 SMART SM00418 11 87 1.6E-9 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TON_1661 880b6174c93ffe45dc6885b0dda19d2b 185 Pfam PF01022 Bacterial regulatory protein, arsR family 19 63 1.9E-12 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TON_1750 cfdbbbbab85cbe36be1a26a38b359d82 366 SUPERFAMILY SSF103486 35 362 1.12E-78 T 23-10-2018 IPR036079 V-type ATP synthase subunit C-like Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TON_1750 cfdbbbbab85cbe36be1a26a38b359d82 366 TIGRFAM TIGR02923 AhaC: ATP synthase A1, C subunit 32 362 2.4E-105 T 23-10-2018 IPR014272 ATPase, V0 complex, c subunit GO:0033179|GO:0046961 TON_1750 cfdbbbbab85cbe36be1a26a38b359d82 366 Gene3D G3DSA:1.10.132.50 35 354 5.3E-60 T 23-10-2018 TON_1750 cfdbbbbab85cbe36be1a26a38b359d82 366 Hamap MF_00314 V-type ATP synthase subunit C [atpC]. 31 363 25.906 T 23-10-2018 IPR014272 ATPase, V0 complex, c subunit GO:0033179|GO:0046961 TON_1750 cfdbbbbab85cbe36be1a26a38b359d82 366 Pfam PF01992 ATP synthase (C/AC39) subunit 39 360 6.4E-66 T 23-10-2018 IPR002843 ATPase, V0 complex, c/d subunit Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TON_1750 cfdbbbbab85cbe36be1a26a38b359d82 366 Gene3D G3DSA:1.20.1690.10 220 323 5.3E-60 T 23-10-2018 IPR035067 V-type ATPase subunit c Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TON_1750 cfdbbbbab85cbe36be1a26a38b359d82 366 Gene3D G3DSA:1.20.1690.10 112 209 5.3E-60 T 23-10-2018 IPR035067 V-type ATPase subunit c Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TON_1763 2a9adb56a90e6a5385a76498f7279633 408 SUPERFAMILY SSF51338 1 398 8.17E-23 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 TON_1763 2a9adb56a90e6a5385a76498f7279633 408 SUPERFAMILY SSF51556 53 335 1.01E-76 T 23-10-2018 IPR032466 Metal-dependent hydrolase TON_1763 2a9adb56a90e6a5385a76498f7279633 408 ProSitePatterns PS00483 Dihydroorotase signature 2. 275 286 - T 23-10-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TON_1763 2a9adb56a90e6a5385a76498f7279633 408 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 14 391 1.2E-121 T 23-10-2018 TON_1763 2a9adb56a90e6a5385a76498f7279633 408 ProSitePatterns PS00482 Dihydroorotase signature 1. 56 64 - T 23-10-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TON_1763 2a9adb56a90e6a5385a76498f7279633 408 Hamap MF_00220_A Dihydroorotase [pyrC]. 4 396 63.418 T 23-10-2018 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TON_1763 2a9adb56a90e6a5385a76498f7279633 408 Gene3D G3DSA:3.20.20.140 43 406 5.7E-107 T 23-10-2018 TON_1763 2a9adb56a90e6a5385a76498f7279633 408 Pfam PF01979 Amidohydrolase family 273 388 2.4E-8 T 23-10-2018 IPR006680 Amidohydrolase-related GO:0016787 TON_1763 2a9adb56a90e6a5385a76498f7279633 408 Pfam PF01979 Amidohydrolase family 49 207 5.1E-13 T 23-10-2018 IPR006680 Amidohydrolase-related GO:0016787 TON_1415 43b227e3721c276d455e0cebe8bf7c39 395 SUPERFAMILY SSF53383 4 391 2.13E-120 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TON_1415 43b227e3721c276d455e0cebe8bf7c39 395 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 238 247 - T 23-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 TON_1415 43b227e3721c276d455e0cebe8bf7c39 395 Gene3D G3DSA:3.40.640.10 55 291 1.6E-140 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TON_1415 43b227e3721c276d455e0cebe8bf7c39 395 Pfam PF00155 Aminotransferase class I and II 40 383 1.9E-70 T 23-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 TON_1415 43b227e3721c276d455e0cebe8bf7c39 395 TIGRFAM TIGR01825 gly_Cac_T_rel: putative pyridoxal phosphate-dependent acyltransferase 7 394 5.0E-202 T 23-10-2018 IPR010962 Putative 8-amino-7-oxononanoate synthase, Archaea/Firmicutes type TON_1415 43b227e3721c276d455e0cebe8bf7c39 395 Gene3D G3DSA:3.90.1150.10 35 385 1.6E-140 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TON_1789 796557253cbb46d3d19e8be9636dc8e5 455 SUPERFAMILY SSF53738 249 351 2.16E-12 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TON_1789 796557253cbb46d3d19e8be9636dc8e5 455 Gene3D G3DSA:3.40.120.10 246 348 1.4E-49 T 23-10-2018 TON_1789 796557253cbb46d3d19e8be9636dc8e5 455 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 149 245 2.1E-24 T 23-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TON_1789 796557253cbb46d3d19e8be9636dc8e5 455 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 363 435 2.3E-12 T 23-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TON_1789 796557253cbb46d3d19e8be9636dc8e5 455 SUPERFAMILY SSF53738 2 169 6.67E-41 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TON_1789 796557253cbb46d3d19e8be9636dc8e5 455 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 250 357 9.9E-8 T 23-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TON_1789 796557253cbb46d3d19e8be9636dc8e5 455 Gene3D G3DSA:3.30.310.50 349 453 4.6E-17 T 23-10-2018 TON_1789 796557253cbb46d3d19e8be9636dc8e5 455 SUPERFAMILY SSF55957 346 448 3.79E-21 T 23-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TON_1789 796557253cbb46d3d19e8be9636dc8e5 455 Gene3D G3DSA:3.40.120.10 1 147 4.7E-45 T 23-10-2018 TON_1789 796557253cbb46d3d19e8be9636dc8e5 455 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 225 240 3.9E-16 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TON_1789 796557253cbb46d3d19e8be9636dc8e5 455 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 197 210 3.9E-16 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TON_1789 796557253cbb46d3d19e8be9636dc8e5 455 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 163 182 3.9E-16 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TON_1789 796557253cbb46d3d19e8be9636dc8e5 455 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 87 101 3.9E-16 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TON_1789 796557253cbb46d3d19e8be9636dc8e5 455 SUPERFAMILY SSF53738 147 248 3.88E-27 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TON_1789 796557253cbb46d3d19e8be9636dc8e5 455 Gene3D G3DSA:3.40.120.10 162 344 1.4E-49 T 23-10-2018 TON_1789 796557253cbb46d3d19e8be9636dc8e5 455 TIGRFAM TIGR03990 Arch_GlmM: phosphoglucosamine mutase 1 442 7.6E-148 T 23-10-2018 IPR024086 Phosphoglucosamine mutase, archaeal type GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TON_1789 796557253cbb46d3d19e8be9636dc8e5 455 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 2 129 2.0E-39 T 23-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TON_1789 796557253cbb46d3d19e8be9636dc8e5 455 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 88 97 - T 23-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TON_1476 4272f3fe23bd0a19e85794164e506447 186 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 11 178 7.0E-44 T 23-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 TON_1476 4272f3fe23bd0a19e85794164e506447 186 TIGRFAM TIGR02175 PorC_KorC: 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate family 2 181 5.1E-79 T 23-10-2018 IPR011894 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate GO:0016625|GO:0055114 TON_1476 4272f3fe23bd0a19e85794164e506447 186 Gene3D G3DSA:3.40.920.10 1 183 5.7E-72 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 TON_1476 4272f3fe23bd0a19e85794164e506447 186 SUPERFAMILY SSF53323 1 180 8.37E-58 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 TON_1063 80e7525694febb4c5c278bc7283f3d0b 129 Pfam PF09868 Uncharacterized protein conserved in archaea (DUF2095) 4 127 6.9E-68 T 23-10-2018 IPR018662 Protein of unknown function DUF2095 TON_0341 143dda83239806621ce2a7589780848b 206 Pfam PF01966 HD domain 35 137 2.5E-20 T 23-10-2018 IPR006674 HD domain TON_0341 143dda83239806621ce2a7589780848b 206 SMART SM00471 30 147 2.5E-11 T 23-10-2018 IPR003607 HD/PDEase domain TON_0341 143dda83239806621ce2a7589780848b 206 Gene3D G3DSA:1.10.3210.50 14 206 4.3E-65 T 23-10-2018 TON_0341 143dda83239806621ce2a7589780848b 206 SUPERFAMILY SSF109604 14 205 2.13E-62 T 23-10-2018 TON_0341 143dda83239806621ce2a7589780848b 206 TIGRFAM TIGR00277 HDIG: HDIG domain 34 96 4.9E-9 T 23-10-2018 IPR006675 HDIG domain TON_1059 d9a52aa2231347be819bae845e04e54e 259 PIRSF PIRSF003092 1 259 2.4E-65 T 23-10-2018 IPR025501 ATP binding protein MinD TON_1059 d9a52aa2231347be819bae845e04e54e 259 Gene3D G3DSA:3.40.50.300 4 233 9.9E-67 T 23-10-2018 TON_1059 d9a52aa2231347be819bae845e04e54e 259 TIGRFAM TIGR01969 minD_arch: cell division ATPase MinD 4 251 4.7E-117 T 23-10-2018 IPR010224 ATP binding protein MinD, archaea TON_1059 d9a52aa2231347be819bae845e04e54e 259 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 6 212 3.5E-24 T 23-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain TON_1059 d9a52aa2231347be819bae845e04e54e 259 SUPERFAMILY SSF52540 3 236 3.36E-58 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_1059 d9a52aa2231347be819bae845e04e54e 259 SMART SM00382 3 163 0.0061 T 23-10-2018 IPR003593 AAA+ ATPase domain TON_1347 5da84eff7813c49db5fe1386304ddc96 425 Pfam PF12698 ABC-2 family transporter protein 20 403 1.3E-34 T 23-10-2018 TON_1347 5da84eff7813c49db5fe1386304ddc96 425 Gene3D G3DSA:3.40.1710.10 42 202 1.2E-34 T 23-10-2018 TON_1531 eb7feb55248f0970e626ae22d84dff65 215 Gene3D G3DSA:3.30.1960.10 1 184 2.4E-52 T 23-10-2018 IPR036602 tRNA wybutosine-synthesizing-like superfamily MetaCyc: PWY-7286|Reactome: R-HSA-6782861 TON_1531 eb7feb55248f0970e626ae22d84dff65 215 Hamap MF_00266 tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase [taw3]. 1 186 27.501 T 23-10-2018 IPR022908 tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase GO:0008175|GO:0030488|GO:0031591 MetaCyc: PWY-7286 TON_1531 eb7feb55248f0970e626ae22d84dff65 215 Pfam PF02676 Methyltransferase TYW3 3 184 2.6E-41 T 23-10-2018 IPR003827 tRNA wybutosine-synthesizing protein MetaCyc: PWY-7286|Reactome: R-HSA-6782861 TON_1531 eb7feb55248f0970e626ae22d84dff65 215 SUPERFAMILY SSF111278 2 183 4.58E-51 T 23-10-2018 IPR036602 tRNA wybutosine-synthesizing-like superfamily MetaCyc: PWY-7286|Reactome: R-HSA-6782861 TON_1051 c796617dbcfbc75ecf76b8f235348afc 255 SUPERFAMILY SSF88713 2 252 1.19E-104 T 23-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 TON_1051 c796617dbcfbc75ecf76b8f235348afc 255 Gene3D G3DSA:3.20.20.370 1 255 1.3E-111 T 23-10-2018 TON_1051 c796617dbcfbc75ecf76b8f235348afc 255 Hamap MF_00691 UPF0271 protein YbgL [ybgL]. 1 245 47.379 T 23-10-2018 IPR005501 UPF0271 family, LamB/YcsF/PxpA KEGG: 00480+3.5.2.9|MetaCyc: PWY-4041|MetaCyc: PWY-7942 TON_1051 c796617dbcfbc75ecf76b8f235348afc 255 Pfam PF03746 LamB/YcsF family 3 241 4.0E-106 T 23-10-2018 IPR005501 UPF0271 family, LamB/YcsF/PxpA KEGG: 00480+3.5.2.9|MetaCyc: PWY-4041|MetaCyc: PWY-7942 TON_0189 a4f8b8163d1a6c2ce8f4494bb829e9b3 573 TIGRFAM TIGR00463 gltX_arch: glutamate--tRNA ligase 3 573 4.1E-212 T 23-10-2018 IPR004526 Glutamyl-tRNA synthetase, archaeal/eukaryotic cytosolic GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 TON_0189 a4f8b8163d1a6c2ce8f4494bb829e9b3 573 Hamap MF_02076 Glutamate--tRNA ligase [gltX]. 7 571 39.879 T 23-10-2018 IPR004526 Glutamyl-tRNA synthetase, archaeal/eukaryotic cytosolic GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 TON_0189 a4f8b8163d1a6c2ce8f4494bb829e9b3 573 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 99 403 4.6E-85 T 23-10-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0004812|GO:0005524|GO:0043039 TON_0189 a4f8b8163d1a6c2ce8f4494bb829e9b3 573 SUPERFAMILY SSF50715 409 570 1.57E-30 T 23-10-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 TON_0189 a4f8b8163d1a6c2ce8f4494bb829e9b3 573 Gene3D G3DSA:2.40.240.10 418 517 4.6E-43 T 23-10-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, N-terminal Reactome: R-HSA-2408517|Reactome: R-HSA-379716 TON_0189 a4f8b8163d1a6c2ce8f4494bb829e9b3 573 Gene3D G3DSA:3.40.50.620 93 408 6.5E-120 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TON_0189 a4f8b8163d1a6c2ce8f4494bb829e9b3 573 Gene3D G3DSA:2.40.240.100 409 572 4.6E-43 T 23-10-2018 TON_0189 a4f8b8163d1a6c2ce8f4494bb829e9b3 573 PRINTS PR00987 Glutamyl-tRNA synthetase signature 103 115 3.7E-21 T 23-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 TON_0189 a4f8b8163d1a6c2ce8f4494bb829e9b3 573 PRINTS PR00987 Glutamyl-tRNA synthetase signature 280 290 3.7E-21 T 23-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 TON_0189 a4f8b8163d1a6c2ce8f4494bb829e9b3 573 PRINTS PR00987 Glutamyl-tRNA synthetase signature 132 145 3.7E-21 T 23-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 TON_0189 a4f8b8163d1a6c2ce8f4494bb829e9b3 573 PRINTS PR00987 Glutamyl-tRNA synthetase signature 296 304 3.7E-21 T 23-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 TON_0189 a4f8b8163d1a6c2ce8f4494bb829e9b3 573 PRINTS PR00987 Glutamyl-tRNA synthetase signature 117 128 3.7E-21 T 23-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 TON_0189 a4f8b8163d1a6c2ce8f4494bb829e9b3 573 Pfam PF03950 tRNA synthetases class I (E and Q), anti-codon binding domain 409 559 6.2E-29 T 23-10-2018 IPR020059 Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 TON_0189 a4f8b8163d1a6c2ce8f4494bb829e9b3 573 SUPERFAMILY SSF52374 99 415 3.49E-90 T 23-10-2018 TON_1089 ef81c6cbd06188442f48f62924590d1c 234 Gene3D G3DSA:3.30.460.10 21 95 4.3E-7 T 23-10-2018 TON_1089 ef81c6cbd06188442f48f62924590d1c 234 Pfam PF01909 Nucleotidyltransferase domain 31 115 3.7E-8 T 23-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 TON_1089 ef81c6cbd06188442f48f62924590d1c 234 PIRSF PIRSF005928 10 232 3.1E-101 T 23-10-2018 IPR009185 Predicted nucleotidyltransferase TON_1089 ef81c6cbd06188442f48f62924590d1c 234 SUPERFAMILY SSF81301 20 73 9.81E-9 T 23-10-2018 TON_1172 5d5b8fc9f9867ff648fb367fc5df523d 111 Gene3D G3DSA:2.30.130.30 1 110 1.8E-40 T 23-10-2018 TON_1172 5d5b8fc9f9867ff648fb367fc5df523d 111 PIRSF PIRSF016134 2 111 2.6E-44 T 23-10-2018 IPR016645 Uncharacterised conserved protein UCP016134 TON_1172 5d5b8fc9f9867ff648fb367fc5df523d 111 Pfam PF04266 ASCH domain 7 108 4.7E-14 T 23-10-2018 IPR007374 ASCH domain TON_1172 5d5b8fc9f9867ff648fb367fc5df523d 111 SMART SM01022 6 109 1.0E-11 T 23-10-2018 IPR007374 ASCH domain TON_1172 5d5b8fc9f9867ff648fb367fc5df523d 111 SUPERFAMILY SSF88697 1 108 9.2E-32 T 23-10-2018 IPR015947 PUA-like superfamily TON_0062 a27e32b783b4f5dbc323e2299fde6ae1 388 Pfam PF07690 Major Facilitator Superfamily 12 209 4.2E-13 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TON_0062 a27e32b783b4f5dbc323e2299fde6ae1 388 Gene3D G3DSA:1.20.1250.20 206 382 1.4E-8 T 23-10-2018 TON_0062 a27e32b783b4f5dbc323e2299fde6ae1 388 SUPERFAMILY SSF103473 8 378 1.44E-26 T 23-10-2018 IPR036259 MFS transporter superfamily TON_0062 a27e32b783b4f5dbc323e2299fde6ae1 388 Gene3D G3DSA:1.20.1250.20 1 198 7.5E-13 T 23-10-2018 TON_1623 90530c9404904a271788669d7fe05539 88 SUPERFAMILY SSF54285 1 86 3.18E-24 T 23-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp TON_1623 90530c9404904a271788669d7fe05539 88 Pfam PF02597 ThiS family 5 88 1.8E-20 T 23-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 TON_1623 90530c9404904a271788669d7fe05539 88 Gene3D G3DSA:3.10.20.30 1 88 5.1E-29 T 23-10-2018 IPR012675 Beta-grasp domain superfamily TON_1623 90530c9404904a271788669d7fe05539 88 TIGRFAM TIGR01687 moaD_arch: MoaD family protein 3 88 1.9E-26 T 23-10-2018 IPR010038 MoaD, archaeal-type TON_1140 6ecf297e3a4e8359f75cb9a63968ad78 80 Gene3D G3DSA:1.20.59.10 1 80 1.2E-25 T 23-10-2018 IPR036979 Chorismate mutase domain superfamily GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 TON_1140 6ecf297e3a4e8359f75cb9a63968ad78 80 SMART SM00830 12 80 1.2E-17 T 23-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 TON_1140 6ecf297e3a4e8359f75cb9a63968ad78 80 Pfam PF01817 Chorismate mutase type II 12 79 1.7E-19 T 23-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 TON_1140 6ecf297e3a4e8359f75cb9a63968ad78 80 SUPERFAMILY SSF48600 7 78 2.9E-20 T 23-10-2018 IPR036263 Chorismate mutase type II superfamily GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 TON_1140 6ecf297e3a4e8359f75cb9a63968ad78 80 TIGRFAM TIGR01808 CM_M_hiGC-arch: chorismate mutase 8 76 4.3E-18 T 23-10-2018 IPR010958 Chorismate mutase, high GC Gram-positive bacteria/archaeal TON_1413 eff7c725322dacab0cba3dabd5cdc335 500 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 50 159 8.3E-14 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TON_1413 eff7c725322dacab0cba3dabd5cdc335 500 Hamap MF_01508 Replication factor C large subunit [rfcL]. 8 432 34.61 T 23-10-2018 IPR023935 Replication factor C, large subunit TON_1413 eff7c725322dacab0cba3dabd5cdc335 500 SMART SM00382 46 163 3.9E-10 T 23-10-2018 IPR003593 AAA+ ATPase domain TON_1413 eff7c725322dacab0cba3dabd5cdc335 500 Gene3D G3DSA:1.10.8.60 164 228 6.1E-12 T 23-10-2018 TON_1413 eff7c725322dacab0cba3dabd5cdc335 500 Gene3D G3DSA:3.40.50.300 7 161 1.2E-36 T 23-10-2018 TON_1413 eff7c725322dacab0cba3dabd5cdc335 500 SUPERFAMILY SSF52540 8 226 3.55E-44 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_0390 16d8b8f91674f9679e36fdc23d82f629 288 Pfam PF12679 ABC-2 family transporter protein 5 287 3.4E-41 T 23-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 TON_0876 6629f3db208bf0f7185a20c4d88614a9 202 SMART SM00664 85 180 2.8E-14 T 23-10-2018 IPR005018 DOMON domain TON_0876 6629f3db208bf0f7185a20c4d88614a9 202 SUPERFAMILY SSF49344 69 180 6.28E-6 T 23-10-2018 TON_0876 6629f3db208bf0f7185a20c4d88614a9 202 Pfam PF03351 DOMON domain 60 179 1.5E-29 T 23-10-2018 IPR005018 DOMON domain TON_1364 359dd6bfa8d5741017a8cbb38f1b0bc8 109 Gene3D G3DSA:3.30.70.1900 2 102 7.5E-31 T 23-10-2018 TON_1364 359dd6bfa8d5741017a8cbb38f1b0bc8 109 TIGRFAM TIGR01877 cas_cas6: CRISPR-associated endoribonuclease Cas6 6 97 2.7E-23 T 23-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 TON_1364 359dd6bfa8d5741017a8cbb38f1b0bc8 109 Pfam PF01881 CRISPR associated protein Cas6 6 98 3.7E-20 T 23-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 TON_0995 5d91cd87765f1a7dc9f654f66ff40ed0 143 Gene3D G3DSA:3.10.330.10 1 77 3.1E-26 T 23-10-2018 TON_0995 5d91cd87765f1a7dc9f654f66ff40ed0 143 SUPERFAMILY SSF54585 2 73 3.2E-9 T 23-10-2018 IPR029067 CDC48 domain 2-like superfamily TON_0995 5d91cd87765f1a7dc9f654f66ff40ed0 143 SMART SM01072 12 74 0.0039 T 23-10-2018 IPR004201 CDC48, domain 2 TON_0995 5d91cd87765f1a7dc9f654f66ff40ed0 143 Gene3D G3DSA:2.40.10.360 81 143 7.9E-17 T 23-10-2018 TON_0836 94eec48a7961e40da1ccc925302c1fe0 202 SUPERFAMILY SSF46785 5 173 5.71E-12 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TON_0836 94eec48a7961e40da1ccc925302c1fe0 202 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 4 20 9.5E-13 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TON_0836 94eec48a7961e40da1ccc925302c1fe0 202 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 20 31 9.5E-13 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TON_0836 94eec48a7961e40da1ccc925302c1fe0 202 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 31 50 9.5E-13 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TON_0836 94eec48a7961e40da1ccc925302c1fe0 202 SMART SM00746 144 180 8.5E-10 T 23-10-2018 IPR011017 TRASH domain TON_0836 94eec48a7961e40da1ccc925302c1fe0 202 Pfam PF08394 Archaeal TRASH domain 144 179 2.2E-20 T 23-10-2018 IPR013603 TRASH transcription regulator C-terminal, archaeal TON_0836 94eec48a7961e40da1ccc925302c1fe0 202 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 20 34 3.3E-5 T 23-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TON_0836 94eec48a7961e40da1ccc925302c1fe0 202 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 34 50 3.3E-5 T 23-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TON_0836 94eec48a7961e40da1ccc925302c1fe0 202 SUPERFAMILY SSF46785 3 60 3.91E-14 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TON_0836 94eec48a7961e40da1ccc925302c1fe0 202 Gene3D G3DSA:1.10.10.10 1 55 9.4E-22 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TON_0836 94eec48a7961e40da1ccc925302c1fe0 202 SMART SM00344 4 103 1.4E-17 T 23-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 TON_0836 94eec48a7961e40da1ccc925302c1fe0 202 Pfam PF13412 Winged helix-turn-helix DNA-binding 4 51 2.7E-15 T 23-10-2018 TON_1792 c75cfe2445a604917995cb65f44ffeb4 1344 TIGRFAM TIGR04288 CGP_CTERM: CGP-CTERM domain 1324 1343 3.7E-6 T 23-10-2018 IPR027552 CGP-CTERM domain TON_1792 c75cfe2445a604917995cb65f44ffeb4 1344 Gene3D G3DSA:2.60.40.1190 1032 1268 2.3E-66 T 23-10-2018 TON_1792 c75cfe2445a604917995cb65f44ffeb4 1344 Gene3D G3DSA:2.60.40.1190 788 1027 1.9E-63 T 23-10-2018 TON_1792 c75cfe2445a604917995cb65f44ffeb4 1344 Gene3D G3DSA:3.20.110.20 221 572 2.4E-22 T 23-10-2018 TON_1792 c75cfe2445a604917995cb65f44ffeb4 1344 SUPERFAMILY SSF88713 31 575 4.89E-65 T 23-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 TON_1792 c75cfe2445a604917995cb65f44ffeb4 1344 SUPERFAMILY SSF49344 1035 1266 9.81E-79 T 23-10-2018 TON_1792 c75cfe2445a604917995cb65f44ffeb4 1344 Pfam PF03065 Glycosyl hydrolase family 57 35 536 6.6E-126 T 23-10-2018 IPR004300 Glycoside hydrolase family 57, N-terminal domain GO:0003824|GO:0005975 TON_1792 c75cfe2445a604917995cb65f44ffeb4 1344 SUPERFAMILY SSF49344 791 1024 2.51E-78 T 23-10-2018 TON_1792 c75cfe2445a604917995cb65f44ffeb4 1344 Pfam PF09985 C-terminal binding-module, SLH-like, of glucodextranase 792 1023 1.4E-75 T 23-10-2018 IPR019248 Glucodextranase-like, C-terminal TON_1792 c75cfe2445a604917995cb65f44ffeb4 1344 Pfam PF09985 C-terminal binding-module, SLH-like, of glucodextranase 1034 1263 1.1E-76 T 23-10-2018 IPR019248 Glucodextranase-like, C-terminal TON_0764 eb70ca95d86912263586808eaa9afc8e 563 PIRSF PIRSF006553 1 563 6.4E-213 T 23-10-2018 IPR005734 DNA topoisomerase VI, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TON_0764 eb70ca95d86912263586808eaa9afc8e 563 Gene3D G3DSA:3.30.565.10 1 231 2.2E-66 T 23-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TON_0764 eb70ca95d86912263586808eaa9afc8e 563 TIGRFAM TIGR01052 top6b: DNA topoisomerase VI, B subunit 10 533 3.0E-231 T 23-10-2018 IPR005734 DNA topoisomerase VI, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TON_0764 eb70ca95d86912263586808eaa9afc8e 563 ProDom PD013790 TOPOISOMERASE ISOMERASE SUBUNIT DNA B VI TYPE II NUCLEOTIDE-BINDING ATP-BINDING 352 549 3.0E-103 T 23-10-2018 IPR015320 DNA topoisomerase VI, subunit B, transducer GO:0003677|GO:0003918|GO:0006265 TON_0764 eb70ca95d86912263586808eaa9afc8e 563 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 32 142 9.9E-11 T 23-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TON_0764 eb70ca95d86912263586808eaa9afc8e 563 Pfam PF09239 Topoisomerase VI B subunit, transducer 353 506 6.8E-57 T 23-10-2018 IPR015320 DNA topoisomerase VI, subunit B, transducer GO:0003677|GO:0003918|GO:0006265 TON_0764 eb70ca95d86912263586808eaa9afc8e 563 SMART SM00387 31 181 1.7E-8 T 23-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TON_0764 eb70ca95d86912263586808eaa9afc8e 563 SUPERFAMILY SSF55874 18 228 1.28E-26 T 23-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TON_0764 eb70ca95d86912263586808eaa9afc8e 563 Gene3D G3DSA:3.30.230.10 352 562 1.0E-71 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TON_0764 eb70ca95d86912263586808eaa9afc8e 563 Hamap MF_00322 Type 2 DNA topoisomerase 6 subunit B [top6B]. 8 549 31.72 T 23-10-2018 IPR005734 DNA topoisomerase VI, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TON_0764 eb70ca95d86912263586808eaa9afc8e 563 SUPERFAMILY SSF54211 352 513 1.14E-60 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TON_0764 eb70ca95d86912263586808eaa9afc8e 563 Gene3D G3DSA:1.10.8.50 232 308 5.3E-9 T 23-10-2018 TON_1845 4eaf787daff7d0730c42374235773150 113 SUPERFAMILY SSF88723 7 103 6.45E-17 T 23-10-2018 IPR029060 PIN-like domain superfamily TON_1845 4eaf787daff7d0730c42374235773150 113 Gene3D G3DSA:3.40.50.1010 40 113 3.4E-15 T 23-10-2018 TON_1845 4eaf787daff7d0730c42374235773150 113 Pfam PF01850 PIN domain 54 102 4.6E-6 T 23-10-2018 IPR002716 PIN domain TON_0607 8954abb80cf16d7ad2694f6581116d8f 152 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 17 149 3.7E-48 T 23-10-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TON_0607 8954abb80cf16d7ad2694f6581116d8f 152 Gene3D G3DSA:3.40.50.960 3 152 1.6E-56 T 23-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TON_0607 8954abb80cf16d7ad2694f6581116d8f 152 SUPERFAMILY SSF52121 6 152 7.59E-55 T 23-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TON_0607 8954abb80cf16d7ad2694f6581116d8f 152 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 10 152 29.654 T 23-10-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TON_0607 8954abb80cf16d7ad2694f6581116d8f 152 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 15 150 3.6E-52 T 23-10-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TON_0067 baf53173633e2194a1384d0949e8a879 255 Gene3D G3DSA:3.40.1370.10 1 255 6.4E-99 T 23-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 TON_0067 baf53173633e2194a1384d0949e8a879 255 Hamap MF_01328_A 50S ribosomal protein L4 [rplD]. 2 253 44.424 T 23-10-2018 IPR019970 Ribosomal protein L4 GO:0003735|GO:0005840|GO:0006412|GO:0019843 TON_0067 baf53173633e2194a1384d0949e8a879 255 TIGRFAM TIGR03672 rpl4p_arch: 50S ribosomal protein uL4 1 252 3.9E-116 T 23-10-2018 IPR019970 Ribosomal protein L4 GO:0003735|GO:0005840|GO:0006412|GO:0019843 TON_0067 baf53173633e2194a1384d0949e8a879 255 ProSitePatterns PS00939 Ribosomal protein L1e signature. 106 132 - T 23-10-2018 IPR013000 Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0067 baf53173633e2194a1384d0949e8a879 255 SUPERFAMILY SSF52166 1 252 1.57E-72 T 23-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 TON_0067 baf53173633e2194a1384d0949e8a879 255 Pfam PF00573 Ribosomal protein L4/L1 family 16 252 1.4E-49 T 23-10-2018 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 TON_1870 33f5b72adb08c1a93c45dc74c561b376 614 Gene3D G3DSA:3.20.70.20 32 594 5.2E-71 T 23-10-2018 TON_1870 33f5b72adb08c1a93c45dc74c561b376 614 SUPERFAMILY SSF51998 23 596 9.16E-129 T 23-10-2018 TON_1870 33f5b72adb08c1a93c45dc74c561b376 614 TIGRFAM TIGR02487 NrdD: anaerobic ribonucleoside-triphosphate reductase 22 611 1.3E-157 T 23-10-2018 IPR012833 Ribonucleoside-triphosphate reductase, anaerobic GO:0006260|GO:0008998|GO:0016491|GO:0055114 KEGG: 00230+1.1.98.6|KEGG: 00240+1.1.98.6|MetaCyc: PWY-7187|MetaCyc: PWY-7220|MetaCyc: PWY-7222 TON_1870 33f5b72adb08c1a93c45dc74c561b376 614 Pfam PF13597 Anaerobic ribonucleoside-triphosphate reductase 22 612 1.5E-151 T 23-10-2018 IPR012833 Ribonucleoside-triphosphate reductase, anaerobic GO:0006260|GO:0008998|GO:0016491|GO:0055114 KEGG: 00230+1.1.98.6|KEGG: 00240+1.1.98.6|MetaCyc: PWY-7187|MetaCyc: PWY-7220|MetaCyc: PWY-7222 TON_1560 2a40fa6f5b2d352f7db918bdbd404658 225 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 173 184 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TON_1560 2a40fa6f5b2d352f7db918bdbd404658 225 Gene3D G3DSA:3.30.70.20 158 220 7.6E-19 T 23-10-2018 TON_1560 2a40fa6f5b2d352f7db918bdbd404658 225 Gene3D G3DSA:3.40.50.700 2 156 9.8E-41 T 23-10-2018 IPR037024 [NiFe]-hydrogenase, small subunit, N-terminal domain superfamily TON_1560 2a40fa6f5b2d352f7db918bdbd404658 225 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 202 213 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TON_1560 2a40fa6f5b2d352f7db918bdbd404658 225 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 14 132 1.9E-23 T 23-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_1560 2a40fa6f5b2d352f7db918bdbd404658 225 Pfam PF13187 4Fe-4S dicluster domain 173 215 3.7E-8 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TON_1560 2a40fa6f5b2d352f7db918bdbd404658 225 SUPERFAMILY SSF56770 3 214 6.15E-36 T 23-10-2018 TON_0180 b088ec2e69e591d5c75ad7330704aaf5 216 ProSitePatterns PS01199 Ribosomal protein L1 signature. 114 133 - T 23-10-2018 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0180 b088ec2e69e591d5c75ad7330704aaf5 216 Hamap MF_01318_A 50S ribosomal protein L1 [rplA]. 4 215 36.985 T 23-10-2018 IPR023669 Ribosomal protein L1, archaea GO:0003723|GO:0003735|GO:0006412|GO:0015934 TON_0180 b088ec2e69e591d5c75ad7330704aaf5 216 Pfam PF00687 Ribosomal protein L1p/L10e family 21 210 9.7E-49 T 23-10-2018 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein TON_0180 b088ec2e69e591d5c75ad7330704aaf5 216 SUPERFAMILY SSF56808 6 214 2.22E-65 T 23-10-2018 IPR023674 Ribosomal protein L1-like TON_0180 b088ec2e69e591d5c75ad7330704aaf5 216 Gene3D G3DSA:3.30.190.20 13 213 3.4E-77 T 23-10-2018 TON_0180 b088ec2e69e591d5c75ad7330704aaf5 216 Gene3D G3DSA:3.40.50.790 59 150 3.4E-77 T 23-10-2018 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich TON_0180 b088ec2e69e591d5c75ad7330704aaf5 216 PIRSF PIRSF002155 1 216 7.9E-68 T 23-10-2018 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0952 b186683778e969cdb6380fbb431ee959 68 SMART SM00746 7 45 6.6E-12 T 23-10-2018 IPR011017 TRASH domain TON_0952 b186683778e969cdb6380fbb431ee959 68 ProSitePatterns PS01073 Ribosomal protein L24e signature. 9 26 - T 23-10-2018 IPR023442 Ribosomal protein L24e, conserved site TON_0952 b186683778e969cdb6380fbb431ee959 68 Pfam PF01246 Ribosomal protein L24e 3 60 2.1E-25 T 23-10-2018 IPR000988 Ribosomal protein L24e-related TON_0952 b186683778e969cdb6380fbb431ee959 68 SUPERFAMILY SSF57716 6 56 6.7E-21 T 23-10-2018 TON_0952 b186683778e969cdb6380fbb431ee959 68 Gene3D G3DSA:2.30.170.20 2 66 9.0E-28 T 23-10-2018 IPR038630 Ribosomal protein L24e/L24 superfamily TON_0952 b186683778e969cdb6380fbb431ee959 68 Hamap MF_00773 50S ribosomal protein L24e [rpl24e]. 2 55 27.684 T 23-10-2018 IPR023438 Ribosomal protein L24e GO:0003735|GO:0005622|GO:0005840|GO:0006412 TON_1707 362c8cc8b2065a849d4ff84888a2b0fc 379 Pfam PF01747 ATP-sulfurylase 164 372 6.9E-87 T 23-10-2018 IPR024951 Sulphate adenylyltransferase catalytic domain GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 TON_1707 362c8cc8b2065a849d4ff84888a2b0fc 379 Gene3D G3DSA:3.10.400.10 1 159 7.7E-48 T 23-10-2018 TON_1707 362c8cc8b2065a849d4ff84888a2b0fc 379 TIGRFAM TIGR00339 sopT: sulfate adenylyltransferase 5 371 6.7E-122 T 23-10-2018 IPR002650 Sulphate adenylyltransferase GO:0000103|GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 TON_1707 362c8cc8b2065a849d4ff84888a2b0fc 379 SUPERFAMILY SSF52374 164 373 1.42E-76 T 23-10-2018 TON_1707 362c8cc8b2065a849d4ff84888a2b0fc 379 Pfam PF14306 PUA-like domain 4 156 1.9E-50 T 23-10-2018 IPR025980 ATP-sulfurylase PUA-like domain KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 TON_1707 362c8cc8b2065a849d4ff84888a2b0fc 379 Gene3D G3DSA:3.40.50.620 164 373 1.7E-89 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TON_1707 362c8cc8b2065a849d4ff84888a2b0fc 379 Hamap MF_00066 Sulfate adenylyltransferase [sat]. 26 376 50.711 T 23-10-2018 IPR020792 Sulphate adenylyltransferase, prokaryotic-type GO:0000103|GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 TON_1707 362c8cc8b2065a849d4ff84888a2b0fc 379 SUPERFAMILY SSF88697 4 161 1.39E-47 T 23-10-2018 IPR015947 PUA-like superfamily TON_0287 6085f9929ca6c4ccf617cb4faa7316e2 336 Gene3D G3DSA:3.30.1330.10 1 153 1.1E-43 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily TON_0287 6085f9929ca6c4ccf617cb4faa7316e2 336 PIRSF PIRSF005644 1 336 2.2E-126 T 23-10-2018 IPR011854 Carbamoyl dehydratase HypE TON_0287 6085f9929ca6c4ccf617cb4faa7316e2 336 Pfam PF02769 AIR synthase related protein, C-terminal domain 160 314 3.4E-34 T 23-10-2018 IPR010918 PurM-like, C-terminal domain TON_0287 6085f9929ca6c4ccf617cb4faa7316e2 336 Gene3D G3DSA:3.90.650.10 154 336 2.8E-58 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily TON_0287 6085f9929ca6c4ccf617cb4faa7316e2 336 SUPERFAMILY SSF55326 3 152 5.68E-31 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily TON_0287 6085f9929ca6c4ccf617cb4faa7316e2 336 Pfam PF00586 AIR synthase related protein, N-terminal domain 40 149 1.5E-16 T 23-10-2018 IPR016188 PurM-like, N-terminal domain TON_0287 6085f9929ca6c4ccf617cb4faa7316e2 336 SUPERFAMILY SSF56042 155 330 1.05E-48 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily TON_0287 6085f9929ca6c4ccf617cb4faa7316e2 336 TIGRFAM TIGR02124 hypE: hydrogenase expression/formation protein HypE 2 336 1.5E-120 T 23-10-2018 IPR011854 Carbamoyl dehydratase HypE TON_1196 0a13a0080f23d79b65ff1ee6cf5bda58 120 SUPERFAMILY SSF52172 1 119 1.01E-40 T 23-10-2018 IPR011006 CheY-like superfamily TON_1196 0a13a0080f23d79b65ff1ee6cf5bda58 120 Pfam PF00072 Response regulator receiver domain 4 114 2.3E-33 T 23-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TON_1196 0a13a0080f23d79b65ff1ee6cf5bda58 120 Gene3D G3DSA:3.40.50.2300 1 120 1.8E-41 T 23-10-2018 TON_1196 0a13a0080f23d79b65ff1ee6cf5bda58 120 SMART SM00448 2 114 2.2E-38 T 23-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TON_1320 f2e7a65831891f101db63e380fc36e6b 380 Pfam PF00534 Glycosyl transferases group 1 191 354 6.2E-45 T 23-10-2018 IPR001296 Glycosyl transferase, family 1 TON_1320 f2e7a65831891f101db63e380fc36e6b 380 Gene3D G3DSA:3.40.50.2000 5 363 3.3E-90 T 23-10-2018 TON_1320 f2e7a65831891f101db63e380fc36e6b 380 SUPERFAMILY SSF53756 1 377 4.85E-98 T 23-10-2018 TON_1320 f2e7a65831891f101db63e380fc36e6b 380 Pfam PF13439 Glycosyltransferase Family 4 14 181 3.0E-27 T 23-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 TON_1320 f2e7a65831891f101db63e380fc36e6b 380 Gene3D G3DSA:3.40.50.2000 179 362 3.3E-90 T 23-10-2018 TON_1843 5bf99fbd4e8d15c88e3eb9f5bc9b9826 333 SUPERFAMILY SSF51735 1 320 5.45E-94 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TON_1843 5bf99fbd4e8d15c88e3eb9f5bc9b9826 333 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 304 4.9E-84 T 23-10-2018 IPR016040 NAD(P)-binding domain TON_1843 5bf99fbd4e8d15c88e3eb9f5bc9b9826 333 TIGRFAM TIGR01181 dTDP_gluc_dehyt: dTDP-glucose 4,6-dehydratase 2 318 2.6E-162 T 23-10-2018 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|KEGG: 00525+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 TON_1843 5bf99fbd4e8d15c88e3eb9f5bc9b9826 333 Gene3D G3DSA:3.90.25.10 177 309 2.9E-132 T 23-10-2018 TON_1843 5bf99fbd4e8d15c88e3eb9f5bc9b9826 333 Gene3D G3DSA:3.40.50.720 4 294 2.9E-132 T 23-10-2018 TON_1004 6dcd35b181d942f8b2c9fb486b593b9a 273 SUPERFAMILY SSF53686 3 270 2.49E-61 T 23-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme TON_1004 6dcd35b181d942f8b2c9fb486b593b9a 273 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 3 257 1.4E-45 T 23-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme TON_1004 6dcd35b181d942f8b2c9fb486b593b9a 273 Gene3D G3DSA:3.40.50.1100 3 263 4.9E-70 T 23-10-2018 TON_1004 6dcd35b181d942f8b2c9fb486b593b9a 273 Gene3D G3DSA:3.40.50.1100 19 120 4.9E-70 T 23-10-2018 TON_0588 6429f2888d0fa4919b75b11f146d6c9c 90 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 34 45 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TON_0588 6429f2888d0fa4919b75b11f146d6c9c 90 SUPERFAMILY SSF54862 26 88 2.73E-15 T 23-10-2018 TON_0588 6429f2888d0fa4919b75b11f146d6c9c 90 Gene3D G3DSA:3.30.70.20 2 90 1.4E-16 T 23-10-2018 TON_0588 6429f2888d0fa4919b75b11f146d6c9c 90 Pfam PF12838 4Fe-4S dicluster domain 34 82 3.2E-11 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TON_0588 6429f2888d0fa4919b75b11f146d6c9c 90 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 71 82 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TON_0828 76cfc8380f9ce38d28ba764d3bad9b03 636 Pfam PF00384 Molybdopterin oxidoreductase 56 430 8.5E-44 T 23-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_0828 76cfc8380f9ce38d28ba764d3bad9b03 636 SMART SM00926 1 53 4.4E-10 T 23-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_0828 76cfc8380f9ce38d28ba764d3bad9b03 636 SUPERFAMILY SSF50692 515 636 8.23E-31 T 23-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily TON_0828 76cfc8380f9ce38d28ba764d3bad9b03 636 Gene3D G3DSA:3.40.50.740 67 450 1.7E-117 T 23-10-2018 TON_0828 76cfc8380f9ce38d28ba764d3bad9b03 636 Gene3D G3DSA:2.40.40.20 509 636 2.0E-28 T 23-10-2018 TON_0828 76cfc8380f9ce38d28ba764d3bad9b03 636 Gene3D G3DSA:2.20.25.90 2 58 3.6E-11 T 23-10-2018 TON_0828 76cfc8380f9ce38d28ba764d3bad9b03 636 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 4 47 2.4E-7 T 23-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_0828 76cfc8380f9ce38d28ba764d3bad9b03 636 SUPERFAMILY SSF53706 4 520 2.22E-136 T 23-10-2018 TON_0828 76cfc8380f9ce38d28ba764d3bad9b03 636 Pfam PF01568 Molydopterin dinucleotide binding domain 535 629 6.4E-20 T 23-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 TON_0828 76cfc8380f9ce38d28ba764d3bad9b03 636 Gene3D G3DSA:3.40.228.10 133 505 1.7E-117 T 23-10-2018 TON_0828 76cfc8380f9ce38d28ba764d3bad9b03 636 Gene3D G3DSA:3.30.2070.10 407 487 1.7E-117 T 23-10-2018 TON_0307 f82c17b47c2bbbaf277b37a1e1f4012d 99 Pfam PF04242 Protein of unknown function (DUF424) 7 97 2.4E-33 T 23-10-2018 IPR007355 Protein of unknown function DUF424 TON_0307 f82c17b47c2bbbaf277b37a1e1f4012d 99 Gene3D G3DSA:3.30.1860.10 1 97 2.4E-35 T 23-10-2018 TON_1091 4edd4fd1ca88d7116c7c9b9b52c5a610 400 SUPERFAMILY SSF63882 7 180 7.33E-56 T 23-10-2018 IPR036135 MoeA, N-terminal and linker domain superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TON_1091 4edd4fd1ca88d7116c7c9b9b52c5a610 400 Pfam PF00994 Probable molybdopterin binding domain 184 320 5.2E-25 T 23-10-2018 IPR001453 MoaB/Mog domain TON_1091 4edd4fd1ca88d7116c7c9b9b52c5a610 400 SUPERFAMILY SSF63867 331 399 2.09E-17 T 23-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TON_1091 4edd4fd1ca88d7116c7c9b9b52c5a610 400 Gene3D G3DSA:2.40.340.10 329 400 1.5E-24 T 23-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TON_1091 4edd4fd1ca88d7116c7c9b9b52c5a610 400 Gene3D G3DSA:3.90.105.10 26 178 3.0E-113 T 23-10-2018 TON_1091 4edd4fd1ca88d7116c7c9b9b52c5a610 400 Gene3D G3DSA:2.170.190.11 49 145 3.0E-113 T 23-10-2018 TON_1091 4edd4fd1ca88d7116c7c9b9b52c5a610 400 Pfam PF03454 MoeA C-terminal region (domain IV) 335 399 4.5E-17 T 23-10-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TON_1091 4edd4fd1ca88d7116c7c9b9b52c5a610 400 SUPERFAMILY SSF53218 181 325 9.03E-43 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily TON_1091 4edd4fd1ca88d7116c7c9b9b52c5a610 400 SMART SM00852 184 321 2.2E-38 T 23-10-2018 IPR001453 MoaB/Mog domain TON_1091 4edd4fd1ca88d7116c7c9b9b52c5a610 400 Gene3D G3DSA:3.40.980.10 179 320 3.0E-113 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily TON_1091 4edd4fd1ca88d7116c7c9b9b52c5a610 400 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 180 317 2.7E-32 T 23-10-2018 IPR001453 MoaB/Mog domain TON_1091 4edd4fd1ca88d7116c7c9b9b52c5a610 400 Pfam PF03453 MoeA N-terminal region (domain I and II) 8 171 8.5E-43 T 23-10-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TON_0645 6faf46be0c7a2c26e8cd40a436f571cf 62 SUPERFAMILY SSF57829 1 56 1.14E-18 T 23-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 TON_0645 6faf46be0c7a2c26e8cd40a436f571cf 62 Hamap MF_00547 50S ribosomal protein L37e [rpl37e]. 2 55 20.009 T 23-10-2018 IPR001569 Ribosomal protein L37e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0645 6faf46be0c7a2c26e8cd40a436f571cf 62 Gene3D G3DSA:2.20.25.30 1 57 2.1E-20 T 23-10-2018 IPR011331 Ribosomal protein L37ae/L37e GO:0003735|GO:0005622|GO:0005840|GO:0006412 TON_0645 6faf46be0c7a2c26e8cd40a436f571cf 62 ProSitePatterns PS01077 Ribosomal protein L37e signature. 4 24 - T 23-10-2018 IPR018267 Ribosomal protein L37e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0645 6faf46be0c7a2c26e8cd40a436f571cf 62 Pfam PF01907 Ribosomal protein L37e 3 56 1.2E-21 T 23-10-2018 IPR001569 Ribosomal protein L37e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0645 6faf46be0c7a2c26e8cd40a436f571cf 62 ProDom PD005132 RIBOSOMAL RRNA-BINDING METAL-BINDING RNA-BINDING ZINC RIBONUCLEOPROTEIN ZINC-FINGER L37 60S L37E 9 51 2.0E-15 T 23-10-2018 IPR001569 Ribosomal protein L37e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0611 3d560d051c7a1523ad4d7c9b804896c5 616 Pfam PF00326 Prolyl oligopeptidase family 412 615 9.6E-54 T 23-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 TON_0611 3d560d051c7a1523ad4d7c9b804896c5 616 SUPERFAMILY SSF50993 2 367 7.85E-45 T 23-10-2018 TON_0611 3d560d051c7a1523ad4d7c9b804896c5 616 Pfam PF02897 Prolyl oligopeptidase, N-terminal beta-propeller domain 2 352 1.5E-19 T 23-10-2018 IPR023302 Peptidase S9A, N-terminal domain GO:0004252|GO:0070008 TON_0611 3d560d051c7a1523ad4d7c9b804896c5 616 Gene3D G3DSA:2.130.10.120 49 362 1.2E-137 T 23-10-2018 TON_0611 3d560d051c7a1523ad4d7c9b804896c5 616 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 475 495 7.3E-51 T 23-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 TON_0611 3d560d051c7a1523ad4d7c9b804896c5 616 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 530 545 7.3E-51 T 23-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 TON_0611 3d560d051c7a1523ad4d7c9b804896c5 616 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 548 570 7.3E-51 T 23-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 TON_0611 3d560d051c7a1523ad4d7c9b804896c5 616 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 421 445 7.3E-51 T 23-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 TON_0611 3d560d051c7a1523ad4d7c9b804896c5 616 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 395 413 7.3E-51 T 23-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 TON_0611 3d560d051c7a1523ad4d7c9b804896c5 616 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 449 468 7.3E-51 T 23-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 TON_0611 3d560d051c7a1523ad4d7c9b804896c5 616 SUPERFAMILY SSF53474 368 614 1.51E-49 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold TON_0611 3d560d051c7a1523ad4d7c9b804896c5 616 Gene3D G3DSA:3.40.50.1820 2 610 1.2E-137 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold TON_1302 c3b703dc914d237f3947511074e5f438 386 Pfam PF02803 Thiolase, C-terminal domain 262 355 2.6E-10 T 23-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 TON_1302 c3b703dc914d237f3947511074e5f438 386 SUPERFAMILY SSF53901 233 384 4.33E-29 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 TON_1302 c3b703dc914d237f3947511074e5f438 386 SUPERFAMILY SSF53901 4 229 6.23E-46 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 TON_1302 c3b703dc914d237f3947511074e5f438 386 PIRSF PIRSF000429 1 383 1.8E-63 T 23-10-2018 IPR002155 Thiolase GO:0016747 TON_1302 c3b703dc914d237f3947511074e5f438 386 Gene3D G3DSA:3.40.47.10 4 385 2.6E-122 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 TON_1302 c3b703dc914d237f3947511074e5f438 386 Pfam PF00108 Thiolase, N-terminal domain 5 220 1.6E-26 T 23-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 TON_1813 a9adc6e88812ff45fc0ec53841491a74 184 Gene3D G3DSA:3.90.1140.10 1 184 2.6E-66 T 23-10-2018 TON_1813 a9adc6e88812ff45fc0ec53841491a74 184 TIGRFAM TIGR02258 2_5_ligase: 2'-5' RNA ligase 1 182 1.1E-54 T 23-10-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 TON_1813 a9adc6e88812ff45fc0ec53841491a74 184 Hamap MF_01940 RNA 2',3'-cyclic phosphodiesterase [thpR]. 1 182 27.03 T 23-10-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 TON_1813 a9adc6e88812ff45fc0ec53841491a74 184 Pfam PF02834 LigT like Phosphoesterase 98 174 1.3E-13 T 23-10-2018 IPR014051 Phosphoesterase, HXTX TON_1813 a9adc6e88812ff45fc0ec53841491a74 184 Pfam PF02834 LigT like Phosphoesterase 11 91 1.2E-20 T 23-10-2018 IPR014051 Phosphoesterase, HXTX TON_1813 a9adc6e88812ff45fc0ec53841491a74 184 SUPERFAMILY SSF55144 1 182 1.03E-46 T 23-10-2018 IPR009097 Cyclic phosphodiesterase TON_0547 388c0a53fae70b334e5d80ac65935d9b 395 SUPERFAMILY SSF52317 59 309 2.9E-9 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like TON_1284 54219d5a68c3419539acc5c86ba0995a 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 21 32 1.4E-15 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TON_1284 54219d5a68c3419539acc5c86ba0995a 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 32 51 1.4E-15 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TON_1284 54219d5a68c3419539acc5c86ba0995a 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 5 21 1.4E-15 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TON_1284 54219d5a68c3419539acc5c86ba0995a 150 Gene3D G3DSA:1.10.10.10 2 55 8.6E-24 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TON_1284 54219d5a68c3419539acc5c86ba0995a 150 Pfam PF01037 Lrp/AsnC ligand binding domain 71 140 1.4E-18 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain TON_1284 54219d5a68c3419539acc5c86ba0995a 150 SMART SM00344 5 111 1.1E-46 T 23-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 TON_1284 54219d5a68c3419539acc5c86ba0995a 150 Pfam PF13412 Winged helix-turn-helix DNA-binding 5 52 2.7E-17 T 23-10-2018 TON_1284 54219d5a68c3419539acc5c86ba0995a 150 SUPERFAMILY SSF54909 65 150 9.12E-22 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel TON_1284 54219d5a68c3419539acc5c86ba0995a 150 SUPERFAMILY SSF46785 5 65 7.21E-18 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TON_1284 54219d5a68c3419539acc5c86ba0995a 150 Gene3D G3DSA:3.30.70.920 57 150 1.6E-27 T 23-10-2018 TON_1619 1d4f53e17787e1ee9531034d4b77b38d 310 Pfam PF13186 Iron-sulfur cluster-binding domain 225 281 1.2E-4 T 23-10-2018 IPR023885 4Fe4S-binding SPASM domain TON_1619 1d4f53e17787e1ee9531034d4b77b38d 310 Gene3D G3DSA:3.20.20.70 80 309 9.5E-10 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TON_1619 1d4f53e17787e1ee9531034d4b77b38d 310 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 222 302 3.5E-9 T 23-10-2018 IPR023885 4Fe4S-binding SPASM domain TON_1619 1d4f53e17787e1ee9531034d4b77b38d 310 SUPERFAMILY SSF102114 219 286 8.24E-9 T 23-10-2018 TON_1280 80a6f19df1b78045f498f29e03105881 353 Pfam PF00288 GHMP kinases N terminal domain 92 156 2.2E-14 T 23-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 TON_1280 80a6f19df1b78045f498f29e03105881 353 PIRSF PIRSF000530 1 353 3.7E-96 T 23-10-2018 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 TON_1280 80a6f19df1b78045f498f29e03105881 353 SUPERFAMILY SSF55060 183 348 2.16E-39 T 23-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily TON_1280 80a6f19df1b78045f498f29e03105881 353 ProSitePatterns PS00106 Galactokinase signature. 8 19 - T 23-10-2018 IPR019741 Galactokinase, conserved site KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 TON_1280 80a6f19df1b78045f498f29e03105881 353 PRINTS PR00473 Galactokinase signature 8 26 2.9E-19 T 23-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 TON_1280 80a6f19df1b78045f498f29e03105881 353 PRINTS PR00473 Galactokinase signature 234 248 2.9E-19 T 23-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 TON_1280 80a6f19df1b78045f498f29e03105881 353 PRINTS PR00473 Galactokinase signature 67 78 2.9E-19 T 23-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 TON_1280 80a6f19df1b78045f498f29e03105881 353 PRINTS PR00473 Galactokinase signature 87 105 2.9E-19 T 23-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 TON_1280 80a6f19df1b78045f498f29e03105881 353 Pfam PF08544 GHMP kinases C terminal 249 329 2.2E-13 T 23-10-2018 IPR013750 GHMP kinase, C-terminal domain TON_1280 80a6f19df1b78045f498f29e03105881 353 SUPERFAMILY SSF54211 2 178 1.06E-48 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TON_1280 80a6f19df1b78045f498f29e03105881 353 PRINTS PR00959 Mevalonate kinase family signature 6 30 7.1E-38 T 23-10-2018 TON_1280 80a6f19df1b78045f498f29e03105881 353 PRINTS PR00959 Mevalonate kinase family signature 297 314 7.1E-38 T 23-10-2018 TON_1280 80a6f19df1b78045f498f29e03105881 353 PRINTS PR00959 Mevalonate kinase family signature 137 156 7.1E-38 T 23-10-2018 TON_1280 80a6f19df1b78045f498f29e03105881 353 PRINTS PR00959 Mevalonate kinase family signature 94 116 7.1E-38 T 23-10-2018 TON_1280 80a6f19df1b78045f498f29e03105881 353 Pfam PF10509 Galactokinase galactose-binding signature 4 38 4.4E-14 T 23-10-2018 IPR019539 Galactokinase galactose-binding domain GO:0005534 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 TON_1280 80a6f19df1b78045f498f29e03105881 353 Gene3D G3DSA:3.30.230.10 2 179 2.4E-55 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TON_1280 80a6f19df1b78045f498f29e03105881 353 Gene3D G3DSA:3.30.70.890 180 350 3.0E-55 T 23-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily TON_1280 80a6f19df1b78045f498f29e03105881 353 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 96 107 - T 23-10-2018 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 TON_1280 80a6f19df1b78045f498f29e03105881 353 TIGRFAM TIGR00131 gal_kin: galactokinase 3 348 3.3E-76 T 23-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 TON_1744 72aa3e19bf8393248adc212af1c565f4 507 Pfam PF07549 SecD/SecF GG Motif 28 53 1.8E-4 T 23-10-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site TON_1744 72aa3e19bf8393248adc212af1c565f4 507 Hamap MF_01463_A Protein translocase subunit SecD [secD]. 6 506 18.78 T 23-10-2018 IPR024912 Protein translocase subunit SecD, archaeal TON_1744 72aa3e19bf8393248adc212af1c565f4 507 Pfam PF02355 Protein export membrane protein 331 490 2.9E-18 T 23-10-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial TON_1744 72aa3e19bf8393248adc212af1c565f4 507 Gene3D G3DSA:3.30.70.3400 35 116 1.8E-9 T 23-10-2018 TON_1744 72aa3e19bf8393248adc212af1c565f4 507 SUPERFAMILY SSF82866 311 492 1.31E-25 T 23-10-2018 TON_1744 72aa3e19bf8393248adc212af1c565f4 507 Gene3D G3DSA:1.20.1640.10 312 499 2.1E-14 T 23-10-2018 TON_0048 1883f8143bbe503271f0fe8a46bdc842 340 PIRSF PIRSF005378 1 339 9.4E-113 T 23-10-2018 IPR000228 RNA 3'-terminal phosphate cyclase GO:0006396 TON_0048 1883f8143bbe503271f0fe8a46bdc842 340 TIGRFAM TIGR03399 RNA_3prim_cycl: RNA 3'-phosphate cyclase 4 324 9.1E-127 T 23-10-2018 IPR017770 RNA 3'-terminal phosphate cyclase type 1 GO:0003963|GO:0006396 TON_0048 1883f8143bbe503271f0fe8a46bdc842 340 Pfam PF05189 RNA 3'-terminal phosphate cyclase (RTC), insert domain 188 275 6.2E-23 T 23-10-2018 IPR013791 RNA 3'-terminal phosphate cyclase, insert domain TON_0048 1883f8143bbe503271f0fe8a46bdc842 340 SUPERFAMILY SSF55205 3 216 5.82E-67 T 23-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 TON_0048 1883f8143bbe503271f0fe8a46bdc842 340 Gene3D G3DSA:3.30.360.20 179 276 1.7E-127 T 23-10-2018 IPR036553 RNA 3'-terminal phosphate cyclase, insert domain superfamily TON_0048 1883f8143bbe503271f0fe8a46bdc842 340 Pfam PF01137 RNA 3'-terminal phosphate cyclase 10 326 6.9E-79 T 23-10-2018 IPR023797 RNA 3'-terminal phosphate cyclase domain TON_0048 1883f8143bbe503271f0fe8a46bdc842 340 SUPERFAMILY SSF55205 276 329 9.15E-5 T 23-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 TON_0048 1883f8143bbe503271f0fe8a46bdc842 340 Hamap MF_00200 RNA 3'-terminal phosphate cyclase [rtcA]. 3 338 40.208 T 23-10-2018 IPR017770 RNA 3'-terminal phosphate cyclase type 1 GO:0003963|GO:0006396 TON_0048 1883f8143bbe503271f0fe8a46bdc842 340 SUPERFAMILY SSF52913 187 279 1.18E-23 T 23-10-2018 IPR036553 RNA 3'-terminal phosphate cyclase, insert domain superfamily TON_0048 1883f8143bbe503271f0fe8a46bdc842 340 Gene3D G3DSA:3.65.10.20 6 321 1.7E-127 T 23-10-2018 IPR037136 RNA 3'-terminal phosphate cyclase domain superfamily TON_0048 1883f8143bbe503271f0fe8a46bdc842 340 ProSitePatterns PS01287 RNA 3'-terminal phosphate cyclase signature. 154 164 - T 23-10-2018 IPR020719 RNA 3'-terminal phosphate cyclase-like, conserved site TON_0053 690fd3e4efdbf5fb87d69c301eab2e62 246 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 15 150 1.4E-23 T 23-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_0053 690fd3e4efdbf5fb87d69c301eab2e62 246 SUPERFAMILY SSF56770 2 212 6.02E-43 T 23-10-2018 TON_0053 690fd3e4efdbf5fb87d69c301eab2e62 246 Gene3D G3DSA:3.40.50.700 3 167 1.4E-36 T 23-10-2018 IPR037024 [NiFe]-hydrogenase, small subunit, N-terminal domain superfamily TON_0237 0a9e90baf39da177100cdbd710a138c1 275 Gene3D G3DSA:2.40.50.140 3 85 3.0E-32 T 23-10-2018 TON_0237 0a9e90baf39da177100cdbd710a138c1 275 Hamap MF_00231 Translation initiation factor 2 subunit alpha [eif2a]. 3 263 34.369 T 23-10-2018 IPR022964 Translation initiation factor 2, alpha subunit, archaeal TON_0237 0a9e90baf39da177100cdbd710a138c1 275 SUPERFAMILY SSF50249 7 87 4.65E-21 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold TON_0237 0a9e90baf39da177100cdbd710a138c1 275 SUPERFAMILY SSF110993 176 260 6.28E-22 T 23-10-2018 IPR024055 Translation initiation factor 2, alpha subunit, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-381042|Reactome: R-HSA-382556|Reactome: R-HSA-72649|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72731 TON_0237 0a9e90baf39da177100cdbd710a138c1 275 Gene3D G3DSA:3.30.70.1130 173 262 4.1E-32 T 23-10-2018 IPR024055 Translation initiation factor 2, alpha subunit, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-381042|Reactome: R-HSA-382556|Reactome: R-HSA-72649|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72731 TON_0237 0a9e90baf39da177100cdbd710a138c1 275 Pfam PF07541 Eukaryotic translation initiation factor 2 alpha subunit 122 233 4.6E-23 T 23-10-2018 IPR011488 Translation initiation factor 2, alpha subunit GO:0003723|GO:0003743 Reactome: R-HSA-156827|Reactome: R-HSA-381042|Reactome: R-HSA-382556|Reactome: R-HSA-72649|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72731 TON_0237 0a9e90baf39da177100cdbd710a138c1 275 Pfam PF00575 S1 RNA binding domain 9 83 3.7E-14 T 23-10-2018 IPR003029 S1 domain GO:0003676 TON_0237 0a9e90baf39da177100cdbd710a138c1 275 SMART SM00316 10 83 4.5E-24 T 23-10-2018 IPR022967 RNA-binding domain, S1 TON_0237 0a9e90baf39da177100cdbd710a138c1 275 Gene3D G3DSA:1.10.150.190 86 171 2.1E-34 T 23-10-2018 IPR024054 Translation initiation factor 2, alpha subunit, middle domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-381042|Reactome: R-HSA-382556|Reactome: R-HSA-72649|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72731 TON_0237 0a9e90baf39da177100cdbd710a138c1 275 SUPERFAMILY SSF116742 85 174 3.14E-24 T 23-10-2018 IPR024054 Translation initiation factor 2, alpha subunit, middle domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-381042|Reactome: R-HSA-382556|Reactome: R-HSA-72649|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72731 TON_1643 8613b978b25c1f104beefb45b591d644 701 Hamap MF_00325 DNA polymerase II small subunit [polB]. 2 691 32.696 T 23-10-2018 IPR011149 DNA polymerase II small subunit, archaeal GO:0003676|GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TON_1643 8613b978b25c1f104beefb45b591d644 701 Gene3D G3DSA:1.10.8.800 2 67 3.4E-23 T 23-10-2018 TON_1643 8613b978b25c1f104beefb45b591d644 701 SUPERFAMILY SSF56300 435 662 1.02E-19 T 23-10-2018 TON_1643 8613b978b25c1f104beefb45b591d644 701 Pfam PF04042 DNA polymerase alpha/epsilon subunit B 435 639 7.1E-15 T 23-10-2018 IPR007185 DNA polymerase alpha/epsilon, subunit B GO:0003677|GO:0003887|GO:0006260 TON_1643 8613b978b25c1f104beefb45b591d644 701 PIRSF PIRSF000803 28 698 2.3E-181 T 23-10-2018 IPR011149 DNA polymerase II small subunit, archaeal GO:0003676|GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TON_1643 8613b978b25c1f104beefb45b591d644 701 Gene3D G3DSA:3.60.21.50 419 673 1.2E-24 T 23-10-2018 TON_0234 1fd5adfa926c911d5c0cbdfea17cff27 59 Pfam PF08279 HTH domain 7 49 3.3E-5 T 23-10-2018 IPR013196 Helix-turn-helix, type 11 TON_0234 1fd5adfa926c911d5c0cbdfea17cff27 59 Gene3D G3DSA:1.10.10.10 3 56 5.8E-12 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TON_0234 1fd5adfa926c911d5c0cbdfea17cff27 59 SUPERFAMILY SSF46785 5 56 2.73E-12 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TON_0331 4fe54b87a9d81bf92291df80415c3b0b 1221 Hamap MF_01125 Reverse gyrase [rgy]. 1 1220 65.53 T 23-10-2018 IPR005736 Reverse gyrase GO:0003677|GO:0003916|GO:0006265 TON_0331 4fe54b87a9d81bf92291df80415c3b0b 1221 Gene3D G3DSA:3.40.50.300 320 501 7.2E-33 T 23-10-2018 TON_0331 4fe54b87a9d81bf92291df80415c3b0b 1221 Gene3D G3DSA:3.40.50.300 546 629 1.5E-14 T 23-10-2018 TON_0331 4fe54b87a9d81bf92291df80415c3b0b 1221 SMART SM00437 916 1172 1.5E-100 T 23-10-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 TON_0331 4fe54b87a9d81bf92291df80415c3b0b 1221 Pfam PF00270 DEAD/DEAH box helicase 88 222 3.5E-12 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 TON_0331 4fe54b87a9d81bf92291df80415c3b0b 1221 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 769 782 1.0E-27 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 TON_0331 4fe54b87a9d81bf92291df80415c3b0b 1221 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 958 967 1.0E-27 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 TON_0331 4fe54b87a9d81bf92291df80415c3b0b 1221 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 1039 1055 1.0E-27 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 TON_0331 4fe54b87a9d81bf92291df80415c3b0b 1221 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 855 873 1.0E-27 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 TON_0331 4fe54b87a9d81bf92291df80415c3b0b 1221 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 1133 1147 1.0E-27 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 TON_0331 4fe54b87a9d81bf92291df80415c3b0b 1221 SMART SM00493 642 795 1.5E-45 T 23-10-2018 IPR006171 TOPRIM domain TON_0331 4fe54b87a9d81bf92291df80415c3b0b 1221 Gene3D G3DSA:1.10.290.10 926 1050 5.2E-144 T 23-10-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 TON_0331 4fe54b87a9d81bf92291df80415c3b0b 1221 SMART SM00436 796 883 1.3E-42 T 23-10-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 TON_0331 4fe54b87a9d81bf92291df80415c3b0b 1221 SUPERFAMILY SSF52540 42 240 3.43E-33 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_0331 4fe54b87a9d81bf92291df80415c3b0b 1221 SUPERFAMILY SSF56712 637 1219 3.4E-144 T 23-10-2018 IPR023405 DNA topoisomerase, type IA, core domain TON_0331 4fe54b87a9d81bf92291df80415c3b0b 1221 SUPERFAMILY SSF52540 326 625 5.98E-38 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_0331 4fe54b87a9d81bf92291df80415c3b0b 1221 Pfam PF01751 Toprim domain 644 805 1.2E-28 T 23-10-2018 IPR006171 TOPRIM domain TON_0331 4fe54b87a9d81bf92291df80415c3b0b 1221 Gene3D G3DSA:3.40.50.140 630 819 1.3E-30 T 23-10-2018 TON_0331 4fe54b87a9d81bf92291df80415c3b0b 1221 Gene3D G3DSA:1.10.460.10 825 1213 5.2E-144 T 23-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 TON_0331 4fe54b87a9d81bf92291df80415c3b0b 1221 Pfam PF01131 DNA topoisomerase 820 1209 3.3E-83 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 TON_0331 4fe54b87a9d81bf92291df80415c3b0b 1221 TIGRFAM TIGR01054 rgy: reverse gyrase 2 1218 0.0 T 23-10-2018 IPR005736 Reverse gyrase GO:0003677|GO:0003916|GO:0006265 TON_0331 4fe54b87a9d81bf92291df80415c3b0b 1221 SMART SM00487 81 331 1.1E-22 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TON_0331 4fe54b87a9d81bf92291df80415c3b0b 1221 Gene3D G3DSA:2.60.510.20 877 1117 5.2E-144 T 23-10-2018 TON_1941 ea1249e0872f84f2cb41820dac6522e0 220 Pfam PF04256 Protein of unknown function (DUF434) 2 56 9.6E-23 T 23-10-2018 IPR007368 Protein of unknown function DUF434 TON_1941 ea1249e0872f84f2cb41820dac6522e0 220 ProDom PD019177 PF1672 MJ0935 ST1363 PH1730 UNCHARACTERIZED ARCHAEAL 2 53 3.0E-15 T 23-10-2018 IPR007368 Protein of unknown function DUF434 TON_0640 116103e007ff95e9fed137e2fce6de69 368 Gene3D G3DSA:1.20.1740.10 1 368 2.1E-15 T 23-10-2018 TON_0640 116103e007ff95e9fed137e2fce6de69 368 Pfam PF03222 Tryptophan/tyrosine permease family 7 363 4.9E-36 T 23-10-2018 IPR018227 Amino acid/polyamine transporter 2 GO:0003333 TON_0361 d270503be8f29ee4785a78f34baf5b31 391 SMART SM00116 139 187 1.2E-11 T 23-10-2018 IPR000644 CBS domain TON_0361 d270503be8f29ee4785a78f34baf5b31 391 SMART SM00116 217 265 2.0E-10 T 23-10-2018 IPR000644 CBS domain TON_0361 d270503be8f29ee4785a78f34baf5b31 391 SMART SM00116 75 123 1.7 T 23-10-2018 IPR000644 CBS domain TON_0361 d270503be8f29ee4785a78f34baf5b31 391 SUPERFAMILY SSF54631 124 261 3.54E-35 T 23-10-2018 TON_0361 d270503be8f29ee4785a78f34baf5b31 391 Gene3D G3DSA:3.10.580.10 130 274 2.8E-36 T 23-10-2018 TON_0361 d270503be8f29ee4785a78f34baf5b31 391 Pfam PF00571 CBS domain 132 183 2.3E-16 T 23-10-2018 IPR000644 CBS domain TON_0361 d270503be8f29ee4785a78f34baf5b31 391 Pfam PF00571 CBS domain 211 261 9.8E-13 T 23-10-2018 IPR000644 CBS domain TON_0361 d270503be8f29ee4785a78f34baf5b31 391 Pfam PF00571 CBS domain 69 122 6.1E-5 T 23-10-2018 IPR000644 CBS domain TON_0361 d270503be8f29ee4785a78f34baf5b31 391 Gene3D G3DSA:3.10.580.10 2 129 2.8E-16 T 23-10-2018 TON_0361 d270503be8f29ee4785a78f34baf5b31 391 PIRSF PIRSF036983 2 391 6.4E-136 T 23-10-2018 IPR014651 Uncharacterised conserved protein, 2xCBS, MJ1404 type TON_0361 d270503be8f29ee4785a78f34baf5b31 391 SUPERFAMILY SSF54631 4 123 1.39E-16 T 23-10-2018 TON_0893 39d49bb78f83da016493a91d901a32bc 777 Pfam PF01966 HD domain 5 105 8.6E-8 T 23-10-2018 IPR006674 HD domain TON_0893 39d49bb78f83da016493a91d901a32bc 777 TIGRFAM TIGR02578 cas_TM1811_Csm1: CRISPR-associated protein Cas10/Csm1, subtype III-A/MTUBE 8 648 2.7E-108 T 23-10-2018 IPR013408 CRISPR-associated protein Csm1 TON_0893 39d49bb78f83da016493a91d901a32bc 777 Gene3D G3DSA:3.30.70.2230 490 657 1.1E-45 T 23-10-2018 TON_0893 39d49bb78f83da016493a91d901a32bc 777 SUPERFAMILY SSF109604 5 104 2.0E-5 T 23-10-2018 TON_0724 ccca2130d7b26065794677d0d8c7322f 205 ProSitePatterns PS00910 Uncharacterized protein family UPF0029 signature. 78 107 - T 23-10-2018 IPR020569 Uncharacterised protein family UPF0029, Impact, conserved site TON_0724 ccca2130d7b26065794677d0d8c7322f 205 Gene3D G3DSA:3.30.230.30 1 130 2.3E-47 T 23-10-2018 IPR036956 Impact, N-terminal domain superfamily TON_0724 ccca2130d7b26065794677d0d8c7322f 205 TIGRFAM TIGR00257 IMPACT_YIGZ: uncharacterized protein, YigZ family 2 198 1.2E-52 T 23-10-2018 IPR015796 Impact family, bacterial/archaeal TON_0724 ccca2130d7b26065794677d0d8c7322f 205 SUPERFAMILY SSF54980 136 198 1.87E-9 T 23-10-2018 IPR035647 EF-G domain III/V-like TON_0724 ccca2130d7b26065794677d0d8c7322f 205 Pfam PF01205 Uncharacterized protein family UPF0029 17 123 7.4E-33 T 23-10-2018 IPR001498 Impact, N-terminal TON_0724 ccca2130d7b26065794677d0d8c7322f 205 SUPERFAMILY SSF54211 3 130 6.45E-42 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TON_0724 ccca2130d7b26065794677d0d8c7322f 205 Pfam PF09186 Domain of unknown function (DUF1949) 139 194 8.3E-12 T 23-10-2018 IPR015269 Uncharacterised domain UPF0029, Impact, C-terminal TON_0569 a90e847eb3ee1fcecf92724eb63bfc32 333 Gene3D G3DSA:3.40.50.720 16 318 3.4E-116 T 23-10-2018 TON_0569 a90e847eb3ee1fcecf92724eb63bfc32 333 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 6 318 1.2E-33 T 23-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 TON_0569 a90e847eb3ee1fcecf92724eb63bfc32 333 Gene3D G3DSA:3.40.50.720 95 286 3.4E-116 T 23-10-2018 TON_0569 a90e847eb3ee1fcecf92724eb63bfc32 333 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 149 176 - T 23-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 TON_0569 a90e847eb3ee1fcecf92724eb63bfc32 333 SUPERFAMILY SSF52283 1 132 4.54E-35 T 23-10-2018 TON_0569 a90e847eb3ee1fcecf92724eb63bfc32 333 SUPERFAMILY SSF51735 98 287 3.4E-54 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TON_0569 a90e847eb3ee1fcecf92724eb63bfc32 333 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 106 286 1.7E-57 T 23-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 TON_1692 77e551230fc0d69fb42b32267fa87a5c 323 ProSitePatterns PS01263 Uncharacterized protein family UPF0021 signature. 22 59 - T 23-10-2018 IPR020554 Uncharacterised protein family UPF0021, conserved site TON_1692 77e551230fc0d69fb42b32267fa87a5c 323 PIRSF PIRSF004976 1 317 1.3E-112 T 23-10-2018 IPR035107 tRNA thiolation protein, TtcA/Ctu1 type GO:0008033 Reactome: R-HSA-6782315 TON_1692 77e551230fc0d69fb42b32267fa87a5c 323 Gene3D G3DSA:3.40.50.620 1 319 5.6E-88 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TON_1692 77e551230fc0d69fb42b32267fa87a5c 323 SUPERFAMILY SSF52402 25 257 5.87E-55 T 23-10-2018 TON_1692 77e551230fc0d69fb42b32267fa87a5c 323 TIGRFAM TIGR00269 TIGR00269: TIGR00269 family protein 204 305 3.3E-37 T 23-10-2018 IPR000541 Cytoplasmic tRNA 2-thiolation protein 1 GO:0000049|GO:0002098|GO:0034227 Reactome: R-HSA-6782315 TON_1692 77e551230fc0d69fb42b32267fa87a5c 323 Pfam PF01171 PP-loop family 50 228 1.5E-15 T 23-10-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 TON_1495 d00c7ccd9c0ddd437abdcde3aed3519c 275 Pfam PF00892 EamA-like transporter family 6 130 8.6E-18 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TON_1495 d00c7ccd9c0ddd437abdcde3aed3519c 275 Pfam PF00892 EamA-like transporter family 145 272 1.2E-14 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TON_1495 d00c7ccd9c0ddd437abdcde3aed3519c 275 SUPERFAMILY SSF103481 177 272 3.01E-6 T 23-10-2018 TON_1495 d00c7ccd9c0ddd437abdcde3aed3519c 275 SUPERFAMILY SSF103481 38 133 3.66E-16 T 23-10-2018 TON_1695 b4e3d5bd5a571a8034e14c13f496f908 294 Gene3D G3DSA:3.90.550.10 1 237 5.4E-63 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TON_1695 b4e3d5bd5a571a8034e14c13f496f908 294 Pfam PF00535 Glycosyl transferase family 2 6 133 9.4E-30 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TON_1695 b4e3d5bd5a571a8034e14c13f496f908 294 SUPERFAMILY SSF53448 3 213 4.57E-58 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TON_1050 1b640023dd04e454275a8b31a2e35b37 228 SUPERFAMILY SSF50891 87 217 1.78E-51 T 23-10-2018 IPR029000 Cyclophilin-like domain superfamily TON_1050 1b640023dd04e454275a8b31a2e35b37 228 Gene3D G3DSA:2.40.100.10 86 224 5.2E-64 T 23-10-2018 IPR029000 Cyclophilin-like domain superfamily TON_1050 1b640023dd04e454275a8b31a2e35b37 228 TIGRFAM TIGR00370 TIGR00370: sensor histidine kinase inhibitor, KipI family 8 210 1.4E-77 T 23-10-2018 IPR010016 KipI family KEGG: 00480+3.5.2.9|MetaCyc: PWY-4041|MetaCyc: PWY-7942 TON_1050 1b640023dd04e454275a8b31a2e35b37 228 SUPERFAMILY SSF160467 4 91 7.98E-23 T 23-10-2018 TON_1050 1b640023dd04e454275a8b31a2e35b37 228 Pfam PF02682 Carboxyltransferase domain, subdomain C and D 3 201 4.1E-80 T 23-10-2018 IPR003833 Carboxyltransferase domain, subdomain C and D TON_1050 1b640023dd04e454275a8b31a2e35b37 228 Gene3D G3DSA:3.30.1360.40 3 82 2.2E-24 T 23-10-2018 TON_1050 1b640023dd04e454275a8b31a2e35b37 228 SMART SM00796 2 201 2.5E-115 T 23-10-2018 IPR003833 Carboxyltransferase domain, subdomain C and D TON_0070 99940c9d918ad27b38c5becdfb2ff035 133 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 33 122 25.877 T 23-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0070 99940c9d918ad27b38c5becdfb2ff035 133 PRINTS PR00975 Ribosomal protein S19 family signature 86 98 2.2E-19 T 23-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0070 99940c9d918ad27b38c5becdfb2ff035 133 PRINTS PR00975 Ribosomal protein S19 family signature 66 85 2.2E-19 T 23-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0070 99940c9d918ad27b38c5becdfb2ff035 133 PRINTS PR00975 Ribosomal protein S19 family signature 98 113 2.2E-19 T 23-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0070 99940c9d918ad27b38c5becdfb2ff035 133 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 35 117 5.9E-27 T 23-10-2018 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 TON_0070 99940c9d918ad27b38c5becdfb2ff035 133 ProSitePatterns PS00323 Ribosomal protein S19 signature. 86 110 - T 23-10-2018 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0070 99940c9d918ad27b38c5becdfb2ff035 133 TIGRFAM TIGR01025 uS19_arch: ribosomal protein uS19 4 133 1.4E-66 T 23-10-2018 IPR005713 Ribosomal protein S19A/S15e GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0070 99940c9d918ad27b38c5becdfb2ff035 133 SUPERFAMILY SSF54570 34 117 1.19E-31 T 23-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0070 99940c9d918ad27b38c5becdfb2ff035 133 Gene3D G3DSA:3.30.860.20 2 133 1.7E-54 T 23-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0070 99940c9d918ad27b38c5becdfb2ff035 133 PIRSF PIRSF002144 1 133 2.5E-41 T 23-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0070 99940c9d918ad27b38c5becdfb2ff035 133 Pfam PF00203 Ribosomal protein S19 35 116 1.0E-36 T 23-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_1354 87b8b4306c6827e6102cd6d2f31a4f74 605 Gene3D G3DSA:3.60.9.10 1 211 4.1E-98 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily TON_1354 87b8b4306c6827e6102cd6d2f31a4f74 605 Gene3D G3DSA:1.10.569.10 242 428 1.7E-153 T 23-10-2018 IPR013984 Aldehyde ferredoxin oxidoreductase, domain 2 TON_1354 87b8b4306c6827e6102cd6d2f31a4f74 605 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 221 602 2.9E-140 T 23-10-2018 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 TON_1354 87b8b4306c6827e6102cd6d2f31a4f74 605 SUPERFAMILY SSF48310 211 604 2.22E-142 T 23-10-2018 IPR036021 Aldehyde ferredoxin oxidoreductase-like, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 TON_1354 87b8b4306c6827e6102cd6d2f31a4f74 605 Gene3D G3DSA:1.10.599.10 240 602 1.7E-153 T 23-10-2018 IPR013985 Aldehyde ferredoxin oxidoreductase, domain 3 GO:0016625|GO:0051536|GO:0055114 KEGG: 00030+1.2.7.5 TON_1354 87b8b4306c6827e6102cd6d2f31a4f74 605 SUPERFAMILY SSF56228 1 209 1.83E-81 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily TON_1354 87b8b4306c6827e6102cd6d2f31a4f74 605 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 6 205 4.2E-86 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 TON_1354 87b8b4306c6827e6102cd6d2f31a4f74 605 SMART SM00790 4 207 1.3E-133 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 TON_0582 f72fccc64f117eda93e05e6d6f84a745 186 SUPERFAMILY SSF53323 1 180 2.75E-42 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 TON_0582 f72fccc64f117eda93e05e6d6f84a745 186 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 11 176 2.2E-34 T 23-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 TON_0582 f72fccc64f117eda93e05e6d6f84a745 186 Gene3D G3DSA:3.40.920.10 1 185 3.0E-56 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 TON_0582 f72fccc64f117eda93e05e6d6f84a745 186 TIGRFAM TIGR02175 PorC_KorC: 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate family 4 176 9.3E-25 T 23-10-2018 IPR011894 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate GO:0016625|GO:0055114 TON_0255 9d8650f19017c016aa52ca8afca8880e 344 Pfam PF01032 FecCD transport family 21 339 1.2E-95 T 23-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 TON_0255 9d8650f19017c016aa52ca8afca8880e 344 Gene3D G3DSA:1.10.3470.10 8 343 6.9E-105 T 23-10-2018 IPR037294 ABC transporter, BtuC-like TON_0255 9d8650f19017c016aa52ca8afca8880e 344 SUPERFAMILY SSF81345 7 339 5.49E-85 T 23-10-2018 IPR037294 ABC transporter, BtuC-like TON_1141 c25f9b4a849255a36fede9d89ca3f058 364 Gene3D G3DSA:3.90.1150.10 18 324 8.6E-77 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TON_1141 c25f9b4a849255a36fede9d89ca3f058 364 SUPERFAMILY SSF53383 11 336 1.11E-74 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TON_1141 c25f9b4a849255a36fede9d89ca3f058 364 Gene3D G3DSA:3.40.640.10 47 247 8.6E-77 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TON_1141 c25f9b4a849255a36fede9d89ca3f058 364 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 197 210 - T 23-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 TON_1141 c25f9b4a849255a36fede9d89ca3f058 364 Pfam PF00155 Aminotransferase class I and II 17 323 5.6E-36 T 23-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 TON_0346 0112c5a22e72c977d7f04b7a27afb43d 416 Hamap MF_01082 tRNA pseudouridine synthase D [truD]. 8 416 29.554 T 23-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 TON_0346 0112c5a22e72c977d7f04b7a27afb43d 416 Gene3D G3DSA:3.30.2350.20 126 411 1.6E-116 T 23-10-2018 TON_0346 0112c5a22e72c977d7f04b7a27afb43d 416 PIRSF PIRSF037016 20 390 3.1E-65 T 23-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 TON_0346 0112c5a22e72c977d7f04b7a27afb43d 416 PIRSF PIRSF037016 388 416 0.016 T 23-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 TON_0346 0112c5a22e72c977d7f04b7a27afb43d 416 SUPERFAMILY SSF55120 7 414 1.32E-92 T 23-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 TON_0346 0112c5a22e72c977d7f04b7a27afb43d 416 Gene3D G3DSA:1.10.1510.30 171 256 1.6E-116 T 23-10-2018 TON_0346 0112c5a22e72c977d7f04b7a27afb43d 416 ProSitePatterns PS01268 Uncharacterized protein family UPF0024 signature. 80 93 - T 23-10-2018 IPR020119 Pseudouridine synthase TruD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 Reactome: R-HSA-6782315 TON_0346 0112c5a22e72c977d7f04b7a27afb43d 416 Gene3D G3DSA:3.30.70.3160 42 125 1.6E-116 T 23-10-2018 TON_0346 0112c5a22e72c977d7f04b7a27afb43d 416 TIGRFAM TIGR00094 tRNA_TruD_broad: tRNA pseudouridine synthase, TruD family 12 415 4.7E-87 T 23-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 TON_0346 0112c5a22e72c977d7f04b7a27afb43d 416 Pfam PF01142 tRNA pseudouridine synthase D (TruD) 11 412 1.7E-135 T 23-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 TON_1159 8d9ba8c12224af44e13813b9cd8f4ea3 156 Gene3D G3DSA:3.40.630.30 8 150 1.7E-24 T 23-10-2018 TON_1159 8d9ba8c12224af44e13813b9cd8f4ea3 156 Pfam PF00583 Acetyltransferase (GNAT) family 20 127 3.2E-13 T 23-10-2018 IPR000182 GNAT domain TON_1159 8d9ba8c12224af44e13813b9cd8f4ea3 156 SUPERFAMILY SSF55729 14 150 5.73E-21 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase TON_1812 189ff321cc10ef1525947b78967d023b 454 SUPERFAMILY SSF81631 152 278 2.98E-37 T 23-10-2018 TON_1812 189ff321cc10ef1525947b78967d023b 454 Pfam PF01909 Nucleotidyltransferase domain 37 140 2.3E-11 T 23-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 TON_1812 189ff321cc10ef1525947b78967d023b 454 TIGRFAM TIGR03671 cca_archaeal: CCA-adding enzyme 6 418 4.6E-139 T 23-10-2018 IPR008229 tRNA nucleotidyltransferase, archaea GO:0001680|GO:0003723|GO:0004810 TON_1812 189ff321cc10ef1525947b78967d023b 454 PIRSF PIRSF005335 1 453 3.0E-149 T 23-10-2018 IPR008229 tRNA nucleotidyltransferase, archaea GO:0001680|GO:0003723|GO:0004810 TON_1812 189ff321cc10ef1525947b78967d023b 454 Gene3D G3DSA:1.10.1410.30 8 277 3.6E-85 T 23-10-2018 TON_1812 189ff321cc10ef1525947b78967d023b 454 SUPERFAMILY SSF55003 264 448 1.92E-35 T 23-10-2018 IPR011068 Nucleotidyltransferase, class I-like, C-terminal GO:0003723|GO:0016779|GO:0031123 TON_1812 189ff321cc10ef1525947b78967d023b 454 Gene3D G3DSA:3.30.70.1550 359 398 3.2E-21 T 23-10-2018 TON_1812 189ff321cc10ef1525947b78967d023b 454 Gene3D G3DSA:3.30.460.10 15 151 3.6E-85 T 23-10-2018 TON_1812 189ff321cc10ef1525947b78967d023b 454 Gene3D G3DSA:3.30.70.590 290 425 3.2E-21 T 23-10-2018 TON_1812 189ff321cc10ef1525947b78967d023b 454 Hamap MF_01264 CCA-adding enzyme [cca]. 1 454 163.137 T 23-10-2018 IPR008229 tRNA nucleotidyltransferase, archaea GO:0001680|GO:0003723|GO:0004810 TON_1812 189ff321cc10ef1525947b78967d023b 454 SUPERFAMILY SSF81301 3 149 5.45E-34 T 23-10-2018 TON_1812 189ff321cc10ef1525947b78967d023b 454 Pfam PF09249 tRNA nucleotidyltransferase, second domain 154 277 5.1E-39 T 23-10-2018 IPR015329 tRNA nucleotidyltransferase, substrate binding GO:0004810|GO:0016437 TON_1451 6e22978a14cf3c01c5066a39d40a44af 718 SMART SM00642 31 413 1.8E-81 T 23-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 TON_1451 6e22978a14cf3c01c5066a39d40a44af 718 SUPERFAMILY SSF51011 422 501 3.6E-16 T 23-10-2018 TON_1451 6e22978a14cf3c01c5066a39d40a44af 718 Pfam PF16657 Maltogenic Amylase, C-terminal domain 422 495 1.3E-8 T 23-10-2018 IPR032091 Maltogenic Amylase, C-terminal TON_1451 6e22978a14cf3c01c5066a39d40a44af 718 SMART SM00632 425 501 3.8E-4 T 23-10-2018 IPR031319 Alpha-amylase, C-terminal domain Reactome: R-HSA-189085 TON_1451 6e22978a14cf3c01c5066a39d40a44af 718 PRINTS PR00110 Alpha-amylase signature 331 343 4.1E-5 T 23-10-2018 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 TON_1451 6e22978a14cf3c01c5066a39d40a44af 718 PRINTS PR00110 Alpha-amylase signature 234 245 4.1E-5 T 23-10-2018 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 TON_1451 6e22978a14cf3c01c5066a39d40a44af 718 PRINTS PR00110 Alpha-amylase signature 133 144 4.1E-5 T 23-10-2018 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 TON_1451 6e22978a14cf3c01c5066a39d40a44af 718 Gene3D G3DSA:2.60.40.10 503 582 4.5E-15 T 23-10-2018 IPR013783 Immunoglobulin-like fold TON_1451 6e22978a14cf3c01c5066a39d40a44af 718 Gene3D G3DSA:2.60.40.1180 416 501 7.4E-13 T 23-10-2018 IPR013780 Glycosyl hydrolase, all-beta TON_1451 6e22978a14cf3c01c5066a39d40a44af 718 Pfam PF00128 Alpha amylase, catalytic domain 62 380 6.2E-55 T 23-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 TON_1451 6e22978a14cf3c01c5066a39d40a44af 718 SUPERFAMILY SSF51445 25 419 4.08E-82 T 23-10-2018 IPR017853 Glycoside hydrolase superfamily TON_1451 6e22978a14cf3c01c5066a39d40a44af 718 SUPERFAMILY SSF81296 504 574 1.11E-11 T 23-10-2018 IPR014756 Immunoglobulin E-set TON_1451 6e22978a14cf3c01c5066a39d40a44af 718 Gene3D G3DSA:3.20.20.80 22 415 1.5E-106 T 23-10-2018 TON_1451 6e22978a14cf3c01c5066a39d40a44af 718 Pfam PF01833 IPT/TIG domain 505 583 1.3E-9 T 23-10-2018 IPR002909 IPT domain TON_1436 f135fee98af73d69dade92f90f229ab7 296 Pfam PF10120 Thiamine-phosphate synthase 134 290 5.3E-48 T 23-10-2018 IPR019293 Thiamine-phosphate synthase ThiN GO:0004789 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 TON_1436 f135fee98af73d69dade92f90f229ab7 296 Gene3D G3DSA:3.40.225.10 122 295 3.5E-46 T 23-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily TON_1436 f135fee98af73d69dade92f90f229ab7 296 SUPERFAMILY SSF53639 126 293 3.81E-48 T 23-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily TON_1436 f135fee98af73d69dade92f90f229ab7 296 Gene3D G3DSA:1.10.10.60 15 52 7.7E-6 T 23-10-2018 TON_1436 f135fee98af73d69dade92f90f229ab7 296 SUPERFAMILY SSF47413 14 61 1.25E-6 T 23-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TON_0383 0cf6c50cfd068798911ec3e664daf0bd 335 SUPERFAMILY SSF52096 82 282 1.74E-36 T 23-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TON_0383 0cf6c50cfd068798911ec3e664daf0bd 335 Gene3D G3DSA:3.90.226.10 96 289 1.6E-53 T 23-10-2018 TON_0383 0cf6c50cfd068798911ec3e664daf0bd 335 TIGRFAM TIGR00706 SppA_dom: signal peptide peptidase SppA, 36K type 90 293 4.9E-68 T 23-10-2018 IPR004635 Peptidase S49, SppA GO:0006508|GO:0008233 TON_0383 0cf6c50cfd068798911ec3e664daf0bd 335 Gene3D G3DSA:3.40.1750.20 188 254 1.6E-53 T 23-10-2018 TON_0383 0cf6c50cfd068798911ec3e664daf0bd 335 Pfam PF01343 Peptidase family S49 150 297 2.8E-39 T 23-10-2018 IPR002142 Peptidase S49 GO:0006508|GO:0008233 TON_1452 2c931f4d91fd7088c4008b0f99f28ccb 220 Pfam PF03192 Pyrococcus protein of unknown function, DUF257 9 210 4.6E-66 T 23-10-2018 IPR005489 Protein of unknown function DUF257 TON_1452 2c931f4d91fd7088c4008b0f99f28ccb 220 Gene3D G3DSA:3.40.50.11570 4 215 1.1E-66 T 23-10-2018 TON_0779 b1626c715696b54eeefb07478fcf601e 94 Gene3D G3DSA:3.10.20.30 1 94 1.6E-25 T 23-10-2018 IPR012675 Beta-grasp domain superfamily TON_0779 b1626c715696b54eeefb07478fcf601e 94 SUPERFAMILY SSF54285 1 94 8.97E-20 T 23-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp TON_0779 b1626c715696b54eeefb07478fcf601e 94 TIGRFAM TIGR01687 moaD_arch: MoaD family protein 2 94 3.1E-22 T 23-10-2018 IPR010038 MoaD, archaeal-type TON_0779 b1626c715696b54eeefb07478fcf601e 94 Pfam PF02597 ThiS family 3 94 2.0E-17 T 23-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 TON_0917 753f936f11e7007b30af945273428205 132 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 14 113 8.8E-15 T 23-10-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis TON_0917 753f936f11e7007b30af945273428205 132 Gene3D G3DSA:3.30.420.130 2 126 2.0E-14 T 23-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily TON_0917 753f936f11e7007b30af945273428205 132 SUPERFAMILY SSF53146 3 114 2.62E-14 T 23-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily TON_1342 d00b2ef1e46832d32183729e40d27bc5 81 Pfam PF01037 Lrp/AsnC ligand binding domain 6 76 5.0E-16 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain TON_1342 d00b2ef1e46832d32183729e40d27bc5 81 SUPERFAMILY SSF54909 2 76 1.61E-16 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel TON_1342 d00b2ef1e46832d32183729e40d27bc5 81 Gene3D G3DSA:3.30.70.920 2 74 3.6E-21 T 23-10-2018 TON_1851 0d041f0563d2d884eadec9f953f58f7d 288 Gene3D G3DSA:3.40.50.720 3 271 8.8E-96 T 23-10-2018 TON_1851 0d041f0563d2d884eadec9f953f58f7d 288 TIGRFAM TIGR01214 rmlD: dTDP-4-dehydrorhamnose reductase 2 282 1.2E-108 T 23-10-2018 IPR005913 dTDP-4-dehydrorhamnose reductase family Reactome: R-HSA-156581|Reactome: R-HSA-5689880 TON_1851 0d041f0563d2d884eadec9f953f58f7d 288 Pfam PF04321 RmlD substrate binding domain 2 283 1.7E-85 T 23-10-2018 IPR029903 RmlD-like substrate binding domain Reactome: R-HSA-156581|Reactome: R-HSA-5689880 TON_1851 0d041f0563d2d884eadec9f953f58f7d 288 SUPERFAMILY SSF51735 2 283 4.29E-86 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TON_1851 0d041f0563d2d884eadec9f953f58f7d 288 Gene3D G3DSA:3.90.25.10 164 277 8.8E-96 T 23-10-2018 TON_1851 0d041f0563d2d884eadec9f953f58f7d 288 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 112 140 - T 23-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 TON_1807 ee780e980e6a1f15b6af67350df1d7ae 623 SUPERFAMILY SSF56228 1 221 1.83E-55 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily TON_1807 ee780e980e6a1f15b6af67350df1d7ae 623 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 6 217 2.2E-60 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 TON_1807 ee780e980e6a1f15b6af67350df1d7ae 623 Gene3D G3DSA:3.60.9.10 1 222 1.2E-68 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily TON_1807 ee780e980e6a1f15b6af67350df1d7ae 623 Gene3D G3DSA:1.10.569.10 255 445 3.5E-76 T 23-10-2018 IPR013984 Aldehyde ferredoxin oxidoreductase, domain 2 TON_1807 ee780e980e6a1f15b6af67350df1d7ae 623 SMART SM00790 4 219 7.6E-89 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 TON_1807 ee780e980e6a1f15b6af67350df1d7ae 623 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 244 607 1.2E-77 T 23-10-2018 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 TON_1807 ee780e980e6a1f15b6af67350df1d7ae 623 SUPERFAMILY SSF48310 224 609 2.09E-85 T 23-10-2018 IPR036021 Aldehyde ferredoxin oxidoreductase-like, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 TON_1807 ee780e980e6a1f15b6af67350df1d7ae 623 Gene3D G3DSA:1.10.599.10 446 607 3.5E-76 T 23-10-2018 IPR013985 Aldehyde ferredoxin oxidoreductase, domain 3 GO:0016625|GO:0051536|GO:0055114 KEGG: 00030+1.2.7.5 TON_1395 340e25fa5e439db259643fb3ca271e43 193 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 11 190 3.4E-34 T 23-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 TON_1395 340e25fa5e439db259643fb3ca271e43 193 Gene3D G3DSA:3.40.920.10 1 193 4.8E-35 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 TON_1395 340e25fa5e439db259643fb3ca271e43 193 SUPERFAMILY SSF53323 2 192 1.2E-27 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 TON_0084 3a6ad973defa1677ebbe855efe8b785c 148 Pfam PF01280 Ribosomal protein L19e 2 143 8.1E-60 T 23-10-2018 IPR000196 Ribosomal protein L19/L19e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0084 3a6ad973defa1677ebbe855efe8b785c 148 Hamap MF_01475 50S ribosomal protein L19e [rpl19e]. 1 147 26.261 T 23-10-2018 IPR000196 Ribosomal protein L19/L19e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0084 3a6ad973defa1677ebbe855efe8b785c 148 Gene3D G3DSA:1.10.1200.240 56 147 3.6E-31 T 23-10-2018 TON_0084 3a6ad973defa1677ebbe855efe8b785c 148 SMART SM01416 1 144 1.5E-90 T 23-10-2018 IPR000196 Ribosomal protein L19/L19e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0084 3a6ad973defa1677ebbe855efe8b785c 148 ProSitePatterns PS00526 Ribosomal protein L19e signature. 5 24 - T 23-10-2018 IPR023638 Ribosomal protein L19/L19e conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0084 3a6ad973defa1677ebbe855efe8b785c 148 Gene3D G3DSA:1.10.1650.10 1 54 1.8E-25 T 23-10-2018 IPR015972 Ribosomal protein L19/L19e, domain 1 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0084 3a6ad973defa1677ebbe855efe8b785c 148 SUPERFAMILY SSF48140 1 141 2.62E-58 T 23-10-2018 IPR035970 Ribosomal protein L19/L19e superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_1538 f6e6ec4af601a537bc1d52582a585faf 158 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 3 142 10.214 T 23-10-2018 IPR022907 VapC family GO:0004540 TON_1538 f6e6ec4af601a537bc1d52582a585faf 158 Gene3D G3DSA:3.40.50.1010 1 139 1.0E-12 T 23-10-2018 TON_1538 f6e6ec4af601a537bc1d52582a585faf 158 SMART SM00670 1 133 4.3E-6 T 23-10-2018 IPR002716 PIN domain TON_1538 f6e6ec4af601a537bc1d52582a585faf 158 SUPERFAMILY SSF88723 3 141 1.29E-15 T 23-10-2018 IPR029060 PIN-like domain superfamily TON_1538 f6e6ec4af601a537bc1d52582a585faf 158 Pfam PF01850 PIN domain 3 132 1.9E-12 T 23-10-2018 IPR002716 PIN domain TON_1195 1810911915b779f5b39fb5541ce22f5d 287 SUPERFAMILY SSF47757 2 68 2.75E-11 T 23-10-2018 TON_1195 1810911915b779f5b39fb5541ce22f5d 287 SUPERFAMILY SSF53335 72 270 1.67E-46 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TON_1195 1810911915b779f5b39fb5541ce22f5d 287 Pfam PF03705 CheR methyltransferase, all-alpha domain 10 59 7.4E-10 T 23-10-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal TON_1195 1810911915b779f5b39fb5541ce22f5d 287 Pfam PF01739 CheR methyltransferase, SAM binding domain 72 261 9.3E-57 T 23-10-2018 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal TON_1195 1810911915b779f5b39fb5541ce22f5d 287 SMART SM00138 14 272 5.3E-76 T 23-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 TON_1195 1810911915b779f5b39fb5541ce22f5d 287 PRINTS PR00996 Glutamate methyltransferase family signature 107 127 1.1E-35 T 23-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 TON_1195 1810911915b779f5b39fb5541ce22f5d 287 PRINTS PR00996 Glutamate methyltransferase family signature 211 225 1.1E-35 T 23-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 TON_1195 1810911915b779f5b39fb5541ce22f5d 287 PRINTS PR00996 Glutamate methyltransferase family signature 143 159 1.1E-35 T 23-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 TON_1195 1810911915b779f5b39fb5541ce22f5d 287 PRINTS PR00996 Glutamate methyltransferase family signature 230 253 1.1E-35 T 23-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 TON_1195 1810911915b779f5b39fb5541ce22f5d 287 PRINTS PR00996 Glutamate methyltransferase family signature 65 77 1.1E-35 T 23-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 TON_1195 1810911915b779f5b39fb5541ce22f5d 287 PRINTS PR00996 Glutamate methyltransferase family signature 28 41 1.1E-35 T 23-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 TON_1195 1810911915b779f5b39fb5541ce22f5d 287 Gene3D G3DSA:3.40.50.150 71 274 2.5E-64 T 23-10-2018 TON_1783 59fb9ee603196743e35ab83fa8a693ab 396 Gene3D G3DSA:3.40.50.150 179 396 4.8E-74 T 23-10-2018 TON_1783 59fb9ee603196743e35ab83fa8a693ab 396 Gene3D G3DSA:2.30.130.10 1 71 6.4E-21 T 23-10-2018 IPR036974 PUA domain superfamily GO:0003723 TON_1783 59fb9ee603196743e35ab83fa8a693ab 396 Pfam PF01472 PUA domain 3 75 5.2E-13 T 23-10-2018 IPR002478 PUA domain GO:0003723 TON_1783 59fb9ee603196743e35ab83fa8a693ab 396 SUPERFAMILY SSF88697 1 70 1.24E-16 T 23-10-2018 IPR015947 PUA-like superfamily TON_1783 59fb9ee603196743e35ab83fa8a693ab 396 Gene3D G3DSA:3.30.750.80 72 178 4.8E-37 T 23-10-2018 TON_1783 59fb9ee603196743e35ab83fa8a693ab 396 SMART SM00359 2 87 1.1E-22 T 23-10-2018 IPR002478 PUA domain GO:0003723 TON_1783 59fb9ee603196743e35ab83fa8a693ab 396 Pfam PF10672 S-adenosylmethionine-dependent methyltransferase 169 334 4.8E-20 T 23-10-2018 IPR019614 S-adenosylmethionine-dependent methyltransferase GO:0008168 TON_1783 59fb9ee603196743e35ab83fa8a693ab 396 SUPERFAMILY SSF53335 78 389 5.09E-70 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TON_0738 383855ba560ed176e765a7600d0686ee 248 Gene3D G3DSA:3.40.50.11590 105 215 4.7E-22 T 23-10-2018 TON_0738 383855ba560ed176e765a7600d0686ee 248 Pfam PF04016 Putative heavy-metal chelation 110 242 4.8E-34 T 23-10-2018 IPR007161 Putative heavy-metal chelation domain TON_0738 383855ba560ed176e765a7600d0686ee 248 Pfam PF13938 Putative heavy-metal chelation 13 90 2.6E-13 T 23-10-2018 IPR025251 Domain of unknown function DUF4213 TON_0738 383855ba560ed176e765a7600d0686ee 248 SUPERFAMILY SSF159713 4 244 1.96E-60 T 23-10-2018 TON_0738 383855ba560ed176e765a7600d0686ee 248 Gene3D G3DSA:3.30.390.100 37 104 4.7E-22 T 23-10-2018 TON_0107 d9e850c83def878ce556f23f3a1af010 142 PIRSF PIRSF002181 1 142 3.3E-43 T 23-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 TON_0107 d9e850c83def878ce556f23f3a1af010 142 ProSitePatterns PS00783 Ribosomal protein L13 signature. 79 102 - T 23-10-2018 IPR023563 Ribosomal protein L13, conserved site GO:0003735|GO:0005840|GO:0006412 TON_0107 d9e850c83def878ce556f23f3a1af010 142 Pfam PF00572 Ribosomal protein L13 3 102 2.1E-11 T 23-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 TON_0107 d9e850c83def878ce556f23f3a1af010 142 Gene3D G3DSA:3.90.1180.10 1 142 1.7E-57 T 23-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 TON_0107 d9e850c83def878ce556f23f3a1af010 142 TIGRFAM TIGR01077 L13_A_E: ribosomal protein uL13 3 142 1.2E-64 T 23-10-2018 IPR005755 Ribosomal protein L13, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 TON_0107 d9e850c83def878ce556f23f3a1af010 142 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 1 132 20.424 T 23-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 TON_0107 d9e850c83def878ce556f23f3a1af010 142 SUPERFAMILY SSF52161 2 142 5.49E-44 T 23-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 TON_1311 5909722b6336d6170dc08f808e7e25ce 202 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 12 193 2.2E-39 T 23-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 TON_1311 5909722b6336d6170dc08f808e7e25ce 202 TIGRFAM TIGR03334 IOR_beta: indolepyruvate ferredoxin oxidoreductase, beta subunit 4 194 4.2E-92 T 23-10-2018 IPR017719 Indolepyruvate ferredoxin oxidoreductase, beta subunit GO:0043805|GO:0055114 TON_1311 5909722b6336d6170dc08f808e7e25ce 202 Gene3D G3DSA:3.40.920.10 1 201 2.0E-49 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 TON_1311 5909722b6336d6170dc08f808e7e25ce 202 SUPERFAMILY SSF53323 4 199 1.44E-44 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 TON_1886 fdd2e4f400ed5f6cc7cd338dd0e1453f 395 TIGRFAM TIGR00529 AF0261: integral membrane protein, TIGR00529 family 5 394 3.9E-137 T 23-10-2018 IPR005253 Conserved hypothetical protein CHP00529 TON_1886 fdd2e4f400ed5f6cc7cd338dd0e1453f 395 Pfam PF04165 Protein of unknown function (DUF401) 6 393 1.1E-66 T 23-10-2018 IPR007294 Protein of unknown function DUF401 TON_0030 9b4e624d5d572a7c68563a4e2ad01458 249 Pfam PF01138 3' exoribonuclease family, domain 1 25 154 8.1E-36 T 23-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TON_0030 9b4e624d5d572a7c68563a4e2ad01458 249 SUPERFAMILY SSF54211 10 180 4.56E-47 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TON_0030 9b4e624d5d572a7c68563a4e2ad01458 249 Hamap MF_00591 Exosome complex component Rrp41 [rrp41]. 6 242 61.648 T 23-10-2018 IPR011807 Exosome complex component Rrp41 GO:0000178|GO:0006401|GO:0016896 TON_0030 9b4e624d5d572a7c68563a4e2ad01458 249 TIGRFAM TIGR02065 ECX1: exosome complex exonuclease 1 9 238 1.5E-121 T 23-10-2018 IPR011807 Exosome complex component Rrp41 GO:0000178|GO:0006401|GO:0016896 TON_0030 9b4e624d5d572a7c68563a4e2ad01458 249 Gene3D G3DSA:3.30.230.70 24 249 9.4E-79 T 23-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TON_0030 9b4e624d5d572a7c68563a4e2ad01458 249 SUPERFAMILY SSF55666 155 244 3.14E-26 T 23-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TON_0030 9b4e624d5d572a7c68563a4e2ad01458 249 Pfam PF03725 3' exoribonuclease family, domain 2 157 222 3.4E-16 T 23-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TON_1363 4307c1c766653afa6283213f35e6a529 300 PIRSF PIRSF004944 1 300 5.0E-113 T 23-10-2018 IPR014426 Uncharacterised protein family UPF0282, hydrolase, metallo-beta-lactamase TON_1363 4307c1c766653afa6283213f35e6a529 300 Pfam PF12706 Beta-lactamase superfamily domain 27 207 4.2E-8 T 23-10-2018 IPR001279 Metallo-beta-lactamase TON_1363 4307c1c766653afa6283213f35e6a529 300 SUPERFAMILY SSF56281 1 262 4.32E-15 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TON_1363 4307c1c766653afa6283213f35e6a529 300 Gene3D G3DSA:3.60.15.10 7 267 3.4E-16 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TON_1363 4307c1c766653afa6283213f35e6a529 300 Hamap MF_01406 UPF0282 protein . 1 286 38.737 T 23-10-2018 IPR014426 Uncharacterised protein family UPF0282, hydrolase, metallo-beta-lactamase TON_0033 ff733e86d6bf96256d93206a4e0d129e 132 Pfam PF04472 Cell division protein SepF 58 130 2.9E-14 T 23-10-2018 IPR007561 Cell division protein SepF/SepF-related GO:0090529 TON_0033 ff733e86d6bf96256d93206a4e0d129e 132 Gene3D G3DSA:3.30.110.150 48 132 2.9E-26 T 23-10-2018 IPR038594 SepF-like superfamily TON_0033 ff733e86d6bf96256d93206a4e0d129e 132 PIRSF PIRSF019313 1 132 3.5E-32 T 23-10-2018 IPR012426 Uncharacterised protein family SepF-related, archaea TON_0483 93ab263818b650b2dbcb0df9d8d37ef8 443 PIRSF PIRSF000521 123 427 6.7E-34 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TON_0483 93ab263818b650b2dbcb0df9d8d37ef8 443 PIRSF PIRSF000521 31 129 1.1E-5 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TON_0483 93ab263818b650b2dbcb0df9d8d37ef8 443 Gene3D G3DSA:3.90.1150.10 7 420 1.1E-148 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TON_0483 93ab263818b650b2dbcb0df9d8d37ef8 443 Gene3D G3DSA:3.40.640.10 59 324 1.1E-148 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TON_0483 93ab263818b650b2dbcb0df9d8d37ef8 443 SUPERFAMILY SSF53383 20 426 4.89E-131 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TON_0483 93ab263818b650b2dbcb0df9d8d37ef8 443 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 241 278 - T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TON_0483 93ab263818b650b2dbcb0df9d8d37ef8 443 Pfam PF00202 Aminotransferase class-III 21 424 3.3E-114 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TON_1124 f495992a878a2ce8769a9e6d7ad4e5e8 238 SUPERFAMILY SSF63999 52 107 1.96E-9 T 23-10-2018 IPR036759 Thiamin pyrophosphokinase, catalytic domain superfamily GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 TON_1124 f495992a878a2ce8769a9e6d7ad4e5e8 238 Hamap MF_02131 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase [mptE]. 7 224 36.674 T 23-10-2018 IPR027510 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, MptE GO:0003848|GO:0005524 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 TON_1124 f495992a878a2ce8769a9e6d7ad4e5e8 238 Pfam PF01973 Protein of unknown function DUF115 49 187 5.1E-27 T 23-10-2018 IPR002826 6-hydroxymethylpterin diphosphokinase MptE-like TON_0177 d349b364238d2cec44076b215b72d2cb 61 Hamap MF_00422 Protein translocase subunit SecE [secE]. 6 61 12.513 T 23-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TON_0177 d349b364238d2cec44076b215b72d2cb 61 TIGRFAM TIGR00327 secE_euk_arch: protein translocase SEC61 complex gamma subunit, archaeal and eukaryotic 5 60 4.4E-20 T 23-10-2018 IPR008158 Protein translocase SEC61 complex, gamma subunit GO:0015031|GO:0015450|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TON_0177 d349b364238d2cec44076b215b72d2cb 61 SUPERFAMILY SSF103456 3 58 4.97E-20 T 23-10-2018 IPR023391 Protein translocase SecE domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TON_0177 d349b364238d2cec44076b215b72d2cb 61 Gene3D G3DSA:1.20.5.820 1 61 1.4E-23 T 23-10-2018 IPR023391 Protein translocase SecE domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TON_0177 d349b364238d2cec44076b215b72d2cb 61 ProSitePatterns PS01067 Protein secE/sec61-gamma signature. 11 39 - T 23-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TON_0874 63cb156a12b843f494617b8fc1f3c530 174 Gene3D G3DSA:3.30.1990.20 140 173 1.4E-10 T 23-10-2018 TON_0874 63cb156a12b843f494617b8fc1f3c530 174 SUPERFAMILY SSF55729 10 164 1.03E-24 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase TON_0874 63cb156a12b843f494617b8fc1f3c530 174 Gene3D G3DSA:3.40.630.30 1 139 2.1E-58 T 23-10-2018 TON_0874 63cb156a12b843f494617b8fc1f3c530 174 Pfam PF00583 Acetyltransferase (GNAT) family 39 155 6.1E-16 T 23-10-2018 IPR000182 GNAT domain TON_1301 8ae22bc770df0ce531a3f1a1bee85a8d 350 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 223 303 9.2E-11 T 23-10-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 TON_1301 8ae22bc770df0ce531a3f1a1bee85a8d 350 Hamap MF_01409 UPF0219 protein . 10 350 61.459 T 23-10-2018 IPR004656 Putative condensing enzyme FabH-related TON_1301 8ae22bc770df0ce531a3f1a1bee85a8d 350 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 110 172 3.0E-5 T 23-10-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 TON_1301 8ae22bc770df0ce531a3f1a1bee85a8d 350 SUPERFAMILY SSF53901 10 169 3.14E-34 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 TON_1301 8ae22bc770df0ce531a3f1a1bee85a8d 350 SUPERFAMILY SSF53901 174 348 1.32E-45 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 TON_1301 8ae22bc770df0ce531a3f1a1bee85a8d 350 TIGRFAM TIGR00748 HMG_CoA_syn_Arc: putative hydroxymethylglutaryl-CoA synthase 10 350 4.3E-195 T 23-10-2018 IPR004656 Putative condensing enzyme FabH-related TON_1301 8ae22bc770df0ce531a3f1a1bee85a8d 350 Gene3D G3DSA:3.40.47.10 8 349 5.1E-73 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 TON_0430 3b9f8d56a8a51449a8fd6567d200aa13 192 Pfam PF00149 Calcineurin-like phosphoesterase 23 134 2.0E-6 T 23-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 TON_0430 3b9f8d56a8a51449a8fd6567d200aa13 192 SUPERFAMILY SSF56300 23 157 1.68E-19 T 23-10-2018 TON_0430 3b9f8d56a8a51449a8fd6567d200aa13 192 Gene3D G3DSA:3.60.21.10 22 163 1.8E-7 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like TON_0985 fe1dd330a0273efcd9ca9e93c6b8b3b1 354 SMART SM00382 28 211 1.7E-14 T 23-10-2018 IPR003593 AAA+ ATPase domain TON_0985 fe1dd330a0273efcd9ca9e93c6b8b3b1 354 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TON_0985 fe1dd330a0273efcd9ca9e93c6b8b3b1 354 Gene3D G3DSA:2.40.50.140 289 340 1.0E-6 T 23-10-2018 TON_0985 fe1dd330a0273efcd9ca9e93c6b8b3b1 354 Pfam PF00005 ABC transporter 19 161 2.5E-34 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TON_0985 fe1dd330a0273efcd9ca9e93c6b8b3b1 354 SUPERFAMILY SSF52540 4 244 2.46E-89 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_0985 fe1dd330a0273efcd9ca9e93c6b8b3b1 354 SUPERFAMILY SSF50331 237 349 1.36E-12 T 23-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal TON_0985 fe1dd330a0273efcd9ca9e93c6b8b3b1 354 Gene3D G3DSA:2.40.50.100 238 347 1.0E-6 T 23-10-2018 TON_0985 fe1dd330a0273efcd9ca9e93c6b8b3b1 354 Pfam PF08402 TOBE domain 276 349 8.9E-7 T 23-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 TON_0985 fe1dd330a0273efcd9ca9e93c6b8b3b1 354 TIGRFAM TIGR01187 potA: polyamine ABC transporter, ATP-binding protein 34 328 3.2E-108 T 23-10-2018 IPR005893 Spermidine/putrescine ABC transporter, ATP-binding subunit GO:0015417|GO:0015846|GO:0043190 TON_0985 fe1dd330a0273efcd9ca9e93c6b8b3b1 354 Gene3D G3DSA:3.40.50.300 1 237 1.3E-78 T 23-10-2018 TON_0161 d4073e516cc8adeb9e7034d29e75437a 255 SMART SM00382 30 228 1.2E-5 T 23-10-2018 IPR003593 AAA+ ATPase domain TON_0161 d4073e516cc8adeb9e7034d29e75437a 255 ProSitePatterns PS00211 ABC transporters family signature. 152 166 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TON_0161 d4073e516cc8adeb9e7034d29e75437a 255 SUPERFAMILY SSF52540 5 234 1.41E-61 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_0161 d4073e516cc8adeb9e7034d29e75437a 255 Pfam PF00005 ABC transporter 22 180 3.1E-31 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TON_0161 d4073e516cc8adeb9e7034d29e75437a 255 Gene3D G3DSA:3.40.50.300 2 255 1.7E-69 T 23-10-2018 TON_0260 720a65dffca8de1c5f976f2004be661f 295 SUPERFAMILY SSF161111 8 206 1.26E-57 T 23-10-2018 IPR027469 Cation efflux transmembrane domain superfamily TON_0260 720a65dffca8de1c5f976f2004be661f 295 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 11 284 6.1E-93 T 23-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 TON_0260 720a65dffca8de1c5f976f2004be661f 295 Gene3D G3DSA:1.20.1510.10 10 205 2.9E-49 T 23-10-2018 IPR027469 Cation efflux transmembrane domain superfamily TON_0260 720a65dffca8de1c5f976f2004be661f 295 Pfam PF01545 Cation efflux family 15 205 1.9E-51 T 23-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 TON_0260 720a65dffca8de1c5f976f2004be661f 295 Gene3D G3DSA:3.30.70.1350 206 284 5.7E-7 T 23-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 TON_0260 720a65dffca8de1c5f976f2004be661f 295 SUPERFAMILY SSF160240 209 282 5.75E-15 T 23-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 TON_0260 720a65dffca8de1c5f976f2004be661f 295 Pfam PF16916 Dimerisation domain of Zinc Transporter 214 282 7.3E-11 T 23-10-2018 IPR027470 Cation efflux protein, cytoplasmic domain TON_1571 bca20a694439001390256a424a6d50da 273 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 20 157 5.4E-23 T 23-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_1571 bca20a694439001390256a424a6d50da 273 Gene3D G3DSA:3.40.50.12280 4 108 2.7E-28 T 23-10-2018 TON_1571 bca20a694439001390256a424a6d50da 273 SUPERFAMILY SSF56770 6 165 9.16E-38 T 23-10-2018 TON_1571 bca20a694439001390256a424a6d50da 273 Gene3D G3DSA:3.40.50.12280 115 179 9.5E-8 T 23-10-2018 TON_1018 953a34c0d9ac5c718af435f8559c0a23 630 SUPERFAMILY SSF56821 9 628 1.57E-208 T 23-10-2018 IPR011254 Prismane-like superfamily GO:0003824|GO:0016491|GO:0055114 TON_1018 953a34c0d9ac5c718af435f8559c0a23 630 Gene3D G3DSA:1.20.1270.30 68 241 2.2E-73 T 23-10-2018 IPR016101 CO dehydrogenase, alpha-bundle GO:0006091|GO:0016151|GO:0018492|GO:0051539|GO:0055114 KEGG: 00633+1.2.7.4|KEGG: 00680+1.2.7.4|KEGG: 00720+1.2.7.4|MetaCyc: PWY-5372|MetaCyc: PWY-6780|MetaCyc: PWY-7784 TON_1018 953a34c0d9ac5c718af435f8559c0a23 630 TIGRFAM TIGR01702 CO_DH_cata: carbon-monoxide dehydrogenase, catalytic subunit 15 627 7.4E-236 T 23-10-2018 IPR010047 Ni-containing CO dehydrogenase GO:0006091|GO:0016151|GO:0018492|GO:0051539|GO:0055114 KEGG: 00633+1.2.7.4|KEGG: 00680+1.2.7.4|KEGG: 00720+1.2.7.4|MetaCyc: PWY-5372|MetaCyc: PWY-6780|MetaCyc: PWY-7784 TON_1018 953a34c0d9ac5c718af435f8559c0a23 630 Gene3D G3DSA:3.40.50.2030 412 625 4.1E-94 T 23-10-2018 IPR016099 Prismane-like, alpha/beta-sandwich GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 TON_1018 953a34c0d9ac5c718af435f8559c0a23 630 PIRSF PIRSF005023 1 629 1.4E-264 T 23-10-2018 IPR010047 Ni-containing CO dehydrogenase GO:0006091|GO:0016151|GO:0018492|GO:0051539|GO:0055114 KEGG: 00633+1.2.7.4|KEGG: 00680+1.2.7.4|KEGG: 00720+1.2.7.4|MetaCyc: PWY-5372|MetaCyc: PWY-6780|MetaCyc: PWY-7784 TON_1018 953a34c0d9ac5c718af435f8559c0a23 630 Pfam PF03063 Prismane/CO dehydrogenase family 50 608 1.8E-173 T 23-10-2018 IPR004137 Hydroxylamine reductase/Ni-containing CO dehydrogenase GO:0016491|GO:0055114 KEGG: 00910+1.7.99.1 TON_1018 953a34c0d9ac5c718af435f8559c0a23 630 Gene3D G3DSA:3.40.50.2030 242 409 3.8E-70 T 23-10-2018 IPR016099 Prismane-like, alpha/beta-sandwich GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 TON_1520 2a9ff726c89846b7a0c8362e41aa2ccf 590 SUPERFAMILY SSF102114 127 393 3.53E-44 T 23-10-2018 TON_1520 2a9ff726c89846b7a0c8362e41aa2ccf 590 Gene3D G3DSA:3.20.20.70 128 400 9.0E-34 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TON_1520 2a9ff726c89846b7a0c8362e41aa2ccf 590 Pfam PF13353 4Fe-4S single cluster domain 142 225 1.7E-6 T 23-10-2018 TON_1520 2a9ff726c89846b7a0c8362e41aa2ccf 590 Pfam PF04055 Radical SAM superfamily 142 301 2.0E-21 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TON_1520 2a9ff726c89846b7a0c8362e41aa2ccf 590 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 144 155 - T 23-10-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TON_0125 69f4a3c4129cceed52b004ffa501dfe9 283 PIRSF PIRSF006593 1 283 6.9E-92 T 23-10-2018 IPR014444 Uncharacterised conserved protein UCP006593 TON_0125 69f4a3c4129cceed52b004ffa501dfe9 283 Pfam PF01937 Protein of unknown function DUF89 4 276 5.3E-48 T 23-10-2018 IPR002791 Domain of unknown function DUF89 TON_0125 69f4a3c4129cceed52b004ffa501dfe9 283 Gene3D G3DSA:1.10.285.20 69 131 1.7E-14 T 23-10-2018 TON_0125 69f4a3c4129cceed52b004ffa501dfe9 283 Gene3D G3DSA:3.40.50.10880 132 283 3.0E-59 T 23-10-2018 TON_0125 69f4a3c4129cceed52b004ffa501dfe9 283 Gene3D G3DSA:1.10.8.380 1 68 3.1E-26 T 23-10-2018 TON_0125 69f4a3c4129cceed52b004ffa501dfe9 283 SUPERFAMILY SSF111321 1 281 9.03E-79 T 23-10-2018 IPR036075 AF1104-like superfamily TON_0276 e908a18cb23fb75f335a99485f81a788 583 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 49 176 5.3E-24 T 23-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_0276 e908a18cb23fb75f335a99485f81a788 583 Gene3D G3DSA:3.30.460.80 7 155 2.2E-18 T 23-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_0276 e908a18cb23fb75f335a99485f81a788 583 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 108 172 2.0E-16 T 23-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_0276 e908a18cb23fb75f335a99485f81a788 583 Pfam PF00374 Nickel-dependent hydrogenase 233 302 5.8E-14 T 23-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 TON_0276 e908a18cb23fb75f335a99485f81a788 583 SUPERFAMILY SSF143243 24 209 1.18E-39 T 23-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_0276 e908a18cb23fb75f335a99485f81a788 583 ProSitePatterns PS00542 Respiratory chain NADH dehydrogenase 30 Kd subunit signature. 136 157 - T 23-10-2018 IPR020396 NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_0276 e908a18cb23fb75f335a99485f81a788 583 Gene3D G3DSA:1.10.645.20 195 552 1.6E-130 T 23-10-2018 IPR038290 NADH-quinone oxidoreductase, subunit D superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_0276 e908a18cb23fb75f335a99485f81a788 583 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 483 552 1.4E-17 T 23-10-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_0276 e908a18cb23fb75f335a99485f81a788 583 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 311 473 3.3E-46 T 23-10-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_0276 e908a18cb23fb75f335a99485f81a788 583 SUPERFAMILY SSF56762 207 552 1.7E-118 T 23-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_1348 b464a4e05da84cc47613f7700594ebef 252 SMART SM00382 28 211 1.5E-8 T 23-10-2018 IPR003593 AAA+ ATPase domain TON_1348 b464a4e05da84cc47613f7700594ebef 252 SUPERFAMILY SSF52540 3 227 4.19E-59 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_1348 b464a4e05da84cc47613f7700594ebef 252 Gene3D G3DSA:3.40.50.300 2 245 3.3E-66 T 23-10-2018 TON_1348 b464a4e05da84cc47613f7700594ebef 252 Pfam PF00005 ABC transporter 19 162 3.4E-28 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TON_1425 f78377c16bbe99a61be8f8fa52463b6f 240 SMART SM00382 24 199 4.1E-18 T 23-10-2018 IPR003593 AAA+ ATPase domain TON_1425 f78377c16bbe99a61be8f8fa52463b6f 240 SUPERFAMILY SSF52540 4 208 3.69E-57 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_1425 f78377c16bbe99a61be8f8fa52463b6f 240 Pfam PF00005 ABC transporter 15 152 9.2E-28 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TON_1425 f78377c16bbe99a61be8f8fa52463b6f 240 Gene3D G3DSA:3.40.50.300 3 234 8.8E-62 T 23-10-2018 TON_0850 d06b02e69cd7ca45f3bfa97496d8aae0 475 TIGRFAM TIGR01980 sufB: FeS assembly protein SufB 29 464 1.2E-188 T 23-10-2018 IPR010231 SUF system FeS cluster assembly, SufB GO:0016226 TON_0850 d06b02e69cd7ca45f3bfa97496d8aae0 475 SUPERFAMILY SSF101960 39 468 1.11E-124 T 23-10-2018 IPR037284 SUF system FeS cluster assembly, SufBD superfamily TON_0850 d06b02e69cd7ca45f3bfa97496d8aae0 475 Pfam PF01458 Uncharacterized protein family (UPF0051) 219 444 4.5E-64 T 23-10-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 TON_1403 36f1668dae1b20e26d39f7f1e98e53f9 279 Gene3D G3DSA:3.40.50.2020 16 138 7.7E-79 T 23-10-2018 TON_1403 36f1668dae1b20e26d39f7f1e98e53f9 279 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 1 277 2.1E-89 T 23-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 TON_1403 36f1668dae1b20e26d39f7f1e98e53f9 279 SMART SM01400 1 110 3.4E-32 T 23-10-2018 TON_1403 36f1668dae1b20e26d39f7f1e98e53f9 279 Hamap MF_00583_A Putative ribose-phosphate pyrophosphokinase [prs]. 1 278 36.757 T 23-10-2018 IPR037514 Ribose-phosphate pyrophosphokinase, archaea GO:0004749 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 TON_1403 36f1668dae1b20e26d39f7f1e98e53f9 279 SUPERFAMILY SSF53271 80 264 1.46E-36 T 23-10-2018 IPR029057 Phosphoribosyltransferase-like TON_1403 36f1668dae1b20e26d39f7f1e98e53f9 279 Pfam PF00156 Phosphoribosyl transferase domain 141 239 4.0E-17 T 23-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 TON_1403 36f1668dae1b20e26d39f7f1e98e53f9 279 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 2 109 1.2E-20 T 23-10-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 TON_1403 36f1668dae1b20e26d39f7f1e98e53f9 279 Gene3D G3DSA:3.40.50.2020 139 263 7.7E-79 T 23-10-2018 TON_1718 56beaa73e22a2d0e2feb916d23145588 484 Pfam PF01946 Thi4 family 7 38 1.3E-6 T 23-10-2018 TON_1718 56beaa73e22a2d0e2feb916d23145588 484 PIRSF PIRSF038984 2 89 7.0E-9 T 23-10-2018 IPR028348 FAD dependent protein TON_1718 56beaa73e22a2d0e2feb916d23145588 484 PIRSF PIRSF038984 131 463 5.0E-24 T 23-10-2018 IPR028348 FAD dependent protein TON_1718 56beaa73e22a2d0e2feb916d23145588 484 SUPERFAMILY SSF51905 1 459 1.93E-29 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TON_1718 56beaa73e22a2d0e2feb916d23145588 484 Gene3D G3DSA:3.50.50.60 417 456 1.0E-6 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TON_1718 56beaa73e22a2d0e2feb916d23145588 484 Gene3D G3DSA:3.50.50.60 2 93 8.5E-19 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TON_1718 56beaa73e22a2d0e2feb916d23145588 484 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 6.1E-10 T 23-10-2018 TON_1718 56beaa73e22a2d0e2feb916d23145588 484 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 415 437 6.1E-10 T 23-10-2018 TON_1074 de66c8ca369ca4a5b3a5007be652ed61 134 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 115 1.1E-24 T 23-10-2018 TON_1074 de66c8ca369ca4a5b3a5007be652ed61 134 TIGRFAM TIGR03081 metmalonyl_epim: methylmalonyl-CoA epimerase 4 130 8.5E-53 T 23-10-2018 IPR017515 Methylmalonyl-CoA epimerase KEGG: 00280+5.1.99.1|KEGG: 00630+5.1.99.1|KEGG: 00640+5.1.99.1|KEGG: 00720+5.1.99.1|MetaCyc: PWY-5741|MetaCyc: PWY-5743|MetaCyc: PWY-5789|MetaCyc: PWY-6728|MetaCyc: PWY-7384|MetaCyc: PWY-7854|Reactome: R-HSA-71032 TON_1074 de66c8ca369ca4a5b3a5007be652ed61 134 SUPERFAMILY SSF54593 1 133 4.79E-34 T 23-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TON_1074 de66c8ca369ca4a5b3a5007be652ed61 134 Gene3D G3DSA:3.10.180.10 1 132 2.3E-42 T 23-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TON_0634 3f8aeb65bd2aee97af9e6cad06329d1c 411 Pfam PF07690 Major Facilitator Superfamily 13 363 1.6E-30 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TON_0634 3f8aeb65bd2aee97af9e6cad06329d1c 411 SUPERFAMILY SSF103473 5 400 5.49E-45 T 23-10-2018 IPR036259 MFS transporter superfamily TON_0634 3f8aeb65bd2aee97af9e6cad06329d1c 411 Gene3D G3DSA:1.20.1250.20 2 396 6.8E-40 T 23-10-2018 TON_0634 3f8aeb65bd2aee97af9e6cad06329d1c 411 TIGRFAM TIGR00900 2A0121: H+ Antiporter protein 9 374 7.1E-103 T 23-10-2018 IPR004751 Drug antiporter protein GO:0015307|GO:0015893 TON_1819 3b0aeee015d3db39a2ac9d4b51115c9c 776 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 89 239 3.6E-19 T 23-10-2018 IPR038731 Glycosyltransferase RgtA/B/C/D-like TON_0974 6d1557bc2adc637b2f6bd6b0c24376cf 263 SUPERFAMILY SSF52540 1 223 2.31E-64 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_0974 6d1557bc2adc637b2f6bd6b0c24376cf 263 Pfam PF00005 ABC transporter 22 162 7.3E-31 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TON_0974 6d1557bc2adc637b2f6bd6b0c24376cf 263 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TON_0974 6d1557bc2adc637b2f6bd6b0c24376cf 263 SMART SM00382 26 210 6.5E-16 T 23-10-2018 IPR003593 AAA+ ATPase domain TON_0974 6d1557bc2adc637b2f6bd6b0c24376cf 263 TIGRFAM TIGR01166 cbiO: cobalt ABC transporter, ATP-binding protein 11 197 2.8E-64 T 23-10-2018 IPR005876 Cobalt transport protein ATP-binding subunit GO:0006824 TON_0974 6d1557bc2adc637b2f6bd6b0c24376cf 263 Gene3D G3DSA:3.40.50.300 1 250 4.7E-71 T 23-10-2018 TON_1535 81baf7d202727367d10159b0b1fd0c21 359 SUPERFAMILY SSF48452 57 191 1.58E-8 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TON_1535 81baf7d202727367d10159b0b1fd0c21 359 Gene3D G3DSA:1.25.40.10 1 359 1.4E-92 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TON_0638 b66159e1e90ca64b39a588ea5964b617 252 SUPERFAMILY SSF53218 1 203 1.83E-40 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily TON_0638 b66159e1e90ca64b39a588ea5964b617 252 Gene3D G3DSA:3.40.980.10 2 179 7.3E-53 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily TON_0638 b66159e1e90ca64b39a588ea5964b617 252 Pfam PF00994 Probable molybdopterin binding domain 4 176 3.1E-35 T 23-10-2018 IPR001453 MoaB/Mog domain TON_0638 b66159e1e90ca64b39a588ea5964b617 252 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 3 174 1.7E-25 T 23-10-2018 IPR001453 MoaB/Mog domain TON_0638 b66159e1e90ca64b39a588ea5964b617 252 SMART SM00852 4 179 1.5E-39 T 23-10-2018 IPR001453 MoaB/Mog domain TON_0198 f256f9e327d3d1f8296c96e150f2db79 436 Gene3D G3DSA:1.20.1250.20 6 281 5.9E-18 T 23-10-2018 TON_0198 f256f9e327d3d1f8296c96e150f2db79 436 Gene3D G3DSA:1.20.1250.20 282 436 2.7E-16 T 23-10-2018 TON_0198 f256f9e327d3d1f8296c96e150f2db79 436 SUPERFAMILY SSF103473 1 428 1.57E-42 T 23-10-2018 IPR036259 MFS transporter superfamily TON_0198 f256f9e327d3d1f8296c96e150f2db79 436 Pfam PF07690 Major Facilitator Superfamily 254 426 1.8E-13 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TON_1197 8355eb35e1a7e063e8d003ad63c421a6 370 Pfam PF00072 Response regulator receiver domain 12 116 4.7E-25 T 23-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TON_1197 8355eb35e1a7e063e8d003ad63c421a6 370 PIRSF PIRSF000876 7 358 3.0E-142 T 23-10-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 TON_1197 8355eb35e1a7e063e8d003ad63c421a6 370 Gene3D G3DSA:3.40.50.180 163 353 6.2E-73 T 23-10-2018 IPR035909 Methylesterase CheB, C-terminal TON_1197 8355eb35e1a7e063e8d003ad63c421a6 370 Hamap MF_00099 Chemotaxis response regulator protein-glutamate methylesterase [cheB]. 10 354 41.1 T 23-10-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 TON_1197 8355eb35e1a7e063e8d003ad63c421a6 370 Pfam PF01339 CheB methylesterase 170 348 9.9E-62 T 23-10-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 TON_1197 8355eb35e1a7e063e8d003ad63c421a6 370 Gene3D G3DSA:3.40.50.2300 7 146 4.5E-36 T 23-10-2018 TON_1197 8355eb35e1a7e063e8d003ad63c421a6 370 SUPERFAMILY SSF52172 9 117 5.83E-31 T 23-10-2018 IPR011006 CheY-like superfamily TON_1197 8355eb35e1a7e063e8d003ad63c421a6 370 SMART SM00448 10 124 1.6E-28 T 23-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TON_1197 8355eb35e1a7e063e8d003ad63c421a6 370 SUPERFAMILY SSF52738 167 354 1.57E-65 T 23-10-2018 IPR035909 Methylesterase CheB, C-terminal TON_1075 022687b33ad5b60871548991c22d07de 319 Pfam PF03308 ArgK protein 18 282 2.3E-102 T 23-10-2018 TON_1075 022687b33ad5b60871548991c22d07de 319 SMART SM00382 44 194 1.6E-4 T 23-10-2018 IPR003593 AAA+ ATPase domain TON_1075 022687b33ad5b60871548991c22d07de 319 SUPERFAMILY SSF52540 2 310 2.83E-81 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_1075 022687b33ad5b60871548991c22d07de 319 Gene3D G3DSA:1.20.5.170 1 42 2.9E-5 T 23-10-2018 TON_1075 022687b33ad5b60871548991c22d07de 319 Gene3D G3DSA:3.40.50.300 43 252 1.7E-88 T 23-10-2018 TON_1075 022687b33ad5b60871548991c22d07de 319 TIGRFAM TIGR00750 lao: LAO/AO transport system ATPase 12 312 5.5E-128 T 23-10-2018 IPR005129 SIMIBI class G3E GTPase, ArgK/MeaB GO:0003924|GO:0005525 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 TON_1964 384fa171b0acf45a798b4604025dbbe3 100 Pfam PF01910 Thiamine-binding protein 4 93 1.3E-31 T 23-10-2018 IPR002767 Thiamine-binding protein TON_1964 384fa171b0acf45a798b4604025dbbe3 100 TIGRFAM TIGR00106 TIGR00106: uncharacterized protein, MTH1187 family 2 97 2.2E-28 T 23-10-2018 IPR002767 Thiamine-binding protein TON_1964 384fa171b0acf45a798b4604025dbbe3 100 Gene3D G3DSA:3.30.70.930 1 97 3.5E-34 T 23-10-2018 IPR029756 MTH1187/YkoF-like TON_1964 384fa171b0acf45a798b4604025dbbe3 100 SUPERFAMILY SSF89957 1 96 1.83E-30 T 23-10-2018 IPR029756 MTH1187/YkoF-like TON_0120 8807ef2b00f8b4d11725d1ff49aaea41 238 SMART SM00530 13 66 0.002 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TON_0120 8807ef2b00f8b4d11725d1ff49aaea41 238 SUPERFAMILY SSF47413 20 62 2.28E-5 T 23-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TON_0120 8807ef2b00f8b4d11725d1ff49aaea41 238 SUPERFAMILY SSF53271 76 237 4.98E-35 T 23-10-2018 IPR029057 Phosphoribosyltransferase-like TON_0120 8807ef2b00f8b4d11725d1ff49aaea41 238 Pfam PF01381 Helix-turn-helix 17 61 5.9E-6 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TON_0120 8807ef2b00f8b4d11725d1ff49aaea41 238 Pfam PF00156 Phosphoribosyl transferase domain 96 214 1.3E-11 T 23-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 TON_0120 8807ef2b00f8b4d11725d1ff49aaea41 238 Gene3D G3DSA:3.40.50.2020 65 238 9.2E-40 T 23-10-2018 TON_1715 fac8bca770945f763576bfead8b7e3c3 1137 SUPERFAMILY SSF49344 930 1088 1.22E-10 T 23-10-2018 TON_1715 fac8bca770945f763576bfead8b7e3c3 1137 Pfam PF07705 CARDB 444 539 1.6E-19 T 23-10-2018 IPR011635 CARDB domain TON_1715 fac8bca770945f763576bfead8b7e3c3 1137 Gene3D G3DSA:2.60.40.1190 23 229 3.1E-5 T 23-10-2018 TON_1715 fac8bca770945f763576bfead8b7e3c3 1137 SUPERFAMILY SSF49344 233 427 2.12E-12 T 23-10-2018 TON_1715 fac8bca770945f763576bfead8b7e3c3 1137 Gene3D G3DSA:2.60.40.10 427 548 2.8E-34 T 23-10-2018 IPR013783 Immunoglobulin-like fold TON_1715 fac8bca770945f763576bfead8b7e3c3 1137 SUPERFAMILY SSF49344 24 221 3.1E-11 T 23-10-2018 TON_0327 ac86119788604e12f7888f50ea64b35f 232 Gene3D G3DSA:3.30.470.20 21 230 8.8E-91 T 23-10-2018 TON_0327 ac86119788604e12f7888f50ea64b35f 232 Gene3D G3DSA:3.30.1490.20 39 116 8.8E-91 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 TON_0327 ac86119788604e12f7888f50ea64b35f 232 SUPERFAMILY SSF56059 23 232 8.31E-51 T 23-10-2018 TON_0327 ac86119788604e12f7888f50ea64b35f 232 Pfam PF13549 ATP-grasp domain 15 231 6.1E-84 T 23-10-2018 TON_0057 eca28923f4d34ed6548fc3f122262072 474 Gene3D G3DSA:1.10.1060.10 7 148 1.7E-36 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 TON_0057 eca28923f4d34ed6548fc3f122262072 474 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 156 456 4.1E-41 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TON_0057 eca28923f4d34ed6548fc3f122262072 474 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 158 177 7.0E-23 T 23-10-2018 TON_0057 eca28923f4d34ed6548fc3f122262072 474 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 296 314 7.0E-23 T 23-10-2018 TON_0057 eca28923f4d34ed6548fc3f122262072 474 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 425 447 7.0E-23 T 23-10-2018 TON_0057 eca28923f4d34ed6548fc3f122262072 474 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 397 413 7.0E-23 T 23-10-2018 TON_0057 eca28923f4d34ed6548fc3f122262072 474 Gene3D G3DSA:3.50.50.60 292 474 6.7E-32 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TON_0057 eca28923f4d34ed6548fc3f122262072 474 Gene3D G3DSA:3.50.50.60 153 281 4.5E-38 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TON_0057 eca28923f4d34ed6548fc3f122262072 474 TIGRFAM TIGR01316 gltA: glutamate synthase (NADPH), homotetrameric 16 471 7.4E-199 T 23-10-2018 IPR006004 Glutamate synthase (NADPH), homotetrameric KEGG: 00195+1.18.1.2|MetaCyc: PWY-101 TON_0057 eca28923f4d34ed6548fc3f122262072 474 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 398 412 9.9E-16 T 23-10-2018 TON_0057 eca28923f4d34ed6548fc3f122262072 474 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 157 179 9.9E-16 T 23-10-2018 TON_0057 eca28923f4d34ed6548fc3f122262072 474 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 296 321 9.9E-16 T 23-10-2018 TON_0057 eca28923f4d34ed6548fc3f122262072 474 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 440 447 9.9E-16 T 23-10-2018 TON_0057 eca28923f4d34ed6548fc3f122262072 474 SUPERFAMILY SSF51971 154 406 1.65E-73 T 23-10-2018 TON_0057 eca28923f4d34ed6548fc3f122262072 474 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 21 138 6.0E-37 T 23-10-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 TON_0057 eca28923f4d34ed6548fc3f122262072 474 SUPERFAMILY SSF46548 4 166 6.28E-32 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 TON_1806 6bd8e65abea0b471f2cf8d4e038aacce 175 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 92 103 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TON_1806 6bd8e65abea0b471f2cf8d4e038aacce 175 SUPERFAMILY SSF54862 7 142 1.83E-31 T 23-10-2018 TON_1806 6bd8e65abea0b471f2cf8d4e038aacce 175 Gene3D G3DSA:3.30.70.20 65 118 3.1E-17 T 23-10-2018 TON_1806 6bd8e65abea0b471f2cf8d4e038aacce 175 Pfam PF13247 4Fe-4S dicluster domain 55 133 1.9E-9 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TON_1806 6bd8e65abea0b471f2cf8d4e038aacce 175 Gene3D G3DSA:3.30.70.20 12 135 3.1E-17 T 23-10-2018 TON_1570 2a8f6b8396b98e6ba3c7260e8910dc51 165 SUPERFAMILY SSF54862 7 108 3.01E-20 T 23-10-2018 TON_1570 2a8f6b8396b98e6ba3c7260e8910dc51 165 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 29 40 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TON_1570 2a8f6b8396b98e6ba3c7260e8910dc51 165 Pfam PF12838 4Fe-4S dicluster domain 29 78 7.6E-14 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TON_1570 2a8f6b8396b98e6ba3c7260e8910dc51 165 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 64 75 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TON_1570 2a8f6b8396b98e6ba3c7260e8910dc51 165 Gene3D G3DSA:3.30.70.3270 7 142 4.2E-20 T 23-10-2018 TON_1394 685201408527230d37d2efbbfbcbb717 388 SUPERFAMILY SSF103473 11 386 2.62E-43 T 23-10-2018 IPR036259 MFS transporter superfamily TON_1394 685201408527230d37d2efbbfbcbb717 388 Gene3D G3DSA:1.20.1250.20 10 200 6.1E-17 T 23-10-2018 TON_1394 685201408527230d37d2efbbfbcbb717 388 Gene3D G3DSA:1.20.1250.20 209 388 9.8E-16 T 23-10-2018 TON_1394 685201408527230d37d2efbbfbcbb717 388 Pfam PF07690 Major Facilitator Superfamily 21 199 1.5E-12 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TON_1016 a88e652279b102e4beb00ce5f08290dc 367 SUPERFAMILY SSF46785 271 359 4.57E-15 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TON_1016 a88e652279b102e4beb00ce5f08290dc 367 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 285 342 2.5E-9 T 23-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TON_1016 a88e652279b102e4beb00ce5f08290dc 367 Gene3D G3DSA:1.10.10.10 258 367 4.1E-20 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TON_0102 4c0462d53e5772f21a76afd09135cd85 149 Gene3D G3DSA:1.10.8.50 1 76 1.2E-26 T 23-10-2018 TON_0102 4c0462d53e5772f21a76afd09135cd85 149 PIRSF PIRSF002134 2 149 6.4E-42 T 23-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0102 4c0462d53e5772f21a76afd09135cd85 149 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 8 148 25.595 T 23-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0102 4c0462d53e5772f21a76afd09135cd85 149 SUPERFAMILY SSF46946 9 148 4.04E-35 T 23-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 TON_0102 4c0462d53e5772f21a76afd09135cd85 149 Gene3D G3DSA:4.10.910.10 88 138 7.6E-21 T 23-10-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0102 4c0462d53e5772f21a76afd09135cd85 149 Pfam PF00416 Ribosomal protein S13/S18 10 137 1.2E-41 T 23-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0102 4c0462d53e5772f21a76afd09135cd85 149 TIGRFAM TIGR03629 uS13_arch: ribosomal protein uS13 4 148 2.7E-62 T 23-10-2018 IPR019977 Ribosomal protein S13, archaeal GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 TON_0102 4c0462d53e5772f21a76afd09135cd85 149 ProSitePatterns PS00646 Ribosomal protein S13 signature. 117 130 - T 23-10-2018 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0606 61d488cda809cf52c87ba79bfbe4b86d 641 SMART SM00382 445 624 1.2E-11 T 23-10-2018 IPR003593 AAA+ ATPase domain TON_0606 61d488cda809cf52c87ba79bfbe4b86d 641 Gene3D G3DSA:3.40.630.30 192 349 3.5E-8 T 23-10-2018 TON_0606 61d488cda809cf52c87ba79bfbe4b86d 641 Gene3D G3DSA:3.40.50.300 413 641 5.6E-40 T 23-10-2018 TON_0606 61d488cda809cf52c87ba79bfbe4b86d 641 SUPERFAMILY SSF52540 422 624 9.03E-35 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_0606 61d488cda809cf52c87ba79bfbe4b86d 641 SUPERFAMILY SSF55729 253 376 1.4E-8 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase TON_0606 61d488cda809cf52c87ba79bfbe4b86d 641 Pfam PF00005 ABC transporter 436 572 1.7E-18 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TON_1202 7c96848c5f6cbe106258ed47dddbfbc2 747 Gene3D G3DSA:1.10.287.950 438 746 3.5E-64 T 23-10-2018 TON_1202 7c96848c5f6cbe106258ed47dddbfbc2 747 SMART SM00304 687 743 65.0 T 23-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TON_1202 7c96848c5f6cbe106258ed47dddbfbc2 747 SMART SM00304 339 397 0.0029 T 23-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TON_1202 7c96848c5f6cbe106258ed47dddbfbc2 747 Gene3D G3DSA:1.20.1480.50 294 403 1.5E-5 T 23-10-2018 TON_1202 7c96848c5f6cbe106258ed47dddbfbc2 747 Gene3D G3DSA:3.30.450.20 103 200 1.1E-26 T 23-10-2018 TON_1202 7c96848c5f6cbe106258ed47dddbfbc2 747 SUPERFAMILY SSF58104 478 746 5.82E-59 T 23-10-2018 TON_1202 7c96848c5f6cbe106258ed47dddbfbc2 747 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 531 676 2.2E-38 T 23-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TON_1202 7c96848c5f6cbe106258ed47dddbfbc2 747 Pfam PF02743 Cache domain 46 290 3.3E-40 T 23-10-2018 IPR033479 Double Cache domain 1 TON_1202 7c96848c5f6cbe106258ed47dddbfbc2 747 SMART SM00283 471 746 8.2E-63 T 23-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TON_1202 7c96848c5f6cbe106258ed47dddbfbc2 747 SUPERFAMILY SSF103190 116 209 1.61E-16 T 23-10-2018 IPR029151 Periplasmic sensor-like domain superfamily TON_0301 214d7e9bf37c1f1adc766ea07d474975 283 Gene3D G3DSA:3.90.420.10 25 195 3.2E-20 T 23-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 TON_0301 214d7e9bf37c1f1adc766ea07d474975 283 SUPERFAMILY SSF56524 175 282 1.01E-10 T 23-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 TON_0301 214d7e9bf37c1f1adc766ea07d474975 283 Pfam PF00174 Oxidoreductase molybdopterin binding domain 74 169 6.2E-20 T 23-10-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 TON_0301 214d7e9bf37c1f1adc766ea07d474975 283 SUPERFAMILY SSF56524 40 169 1.57E-27 T 23-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 TON_0031 9f02c07642973aab6280d79bd7057fd1 272 SUPERFAMILY SSF55666 187 269 1.01E-23 T 23-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TON_0031 9f02c07642973aab6280d79bd7057fd1 272 Hamap MF_00622 Exosome complex component Rrp42 [rrp42]. 3 268 45.59 T 23-10-2018 IPR020869 Exosome complex component Rrp42, archaea GO:0000178|GO:0006401 TON_0031 9f02c07642973aab6280d79bd7057fd1 272 Pfam PF03725 3' exoribonuclease family, domain 2 192 255 8.0E-15 T 23-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TON_0031 9f02c07642973aab6280d79bd7057fd1 272 Pfam PF01138 3' exoribonuclease family, domain 1 33 167 3.4E-29 T 23-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TON_0031 9f02c07642973aab6280d79bd7057fd1 272 SUPERFAMILY SSF54211 12 215 2.13E-54 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TON_0031 9f02c07642973aab6280d79bd7057fd1 272 Gene3D G3DSA:3.30.230.70 1 271 1.7E-87 T 23-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TON_0479 e9a70b660ca0ddc816c5555cf017c23b 446 Pfam PF13596 PAS domain 326 429 3.5E-24 T 23-10-2018 TON_0479 e9a70b660ca0ddc816c5555cf017c23b 446 SUPERFAMILY SSF55785 324 422 4.19E-8 T 23-10-2018 IPR035965 PAS domain superfamily TON_0479 e9a70b660ca0ddc816c5555cf017c23b 446 Gene3D G3DSA:3.30.450.20 307 442 1.0E-46 T 23-10-2018 TON_0479 e9a70b660ca0ddc816c5555cf017c23b 446 Pfam PF01814 Hemerythrin HHE cation binding domain 94 233 1.9E-20 T 23-10-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 TON_0479 e9a70b660ca0ddc816c5555cf017c23b 446 Gene3D G3DSA:1.20.120.520 87 306 5.5E-59 T 23-10-2018 TON_0479 e9a70b660ca0ddc816c5555cf017c23b 446 Pfam PF04282 Family of unknown function (DUF438) 15 80 1.5E-25 T 23-10-2018 IPR007380 Domain of unknown function DUF438 TON_0010 9e703385c9376f3ddba6cd565e14e797 392 Gene3D G3DSA:1.20.1250.20 230 392 4.5E-21 T 23-10-2018 TON_0010 9e703385c9376f3ddba6cd565e14e797 392 SUPERFAMILY SSF103473 5 391 1.96E-59 T 23-10-2018 IPR036259 MFS transporter superfamily TON_0010 9e703385c9376f3ddba6cd565e14e797 392 Pfam PF07690 Major Facilitator Superfamily 19 265 2.4E-28 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TON_0010 9e703385c9376f3ddba6cd565e14e797 392 Gene3D G3DSA:1.20.1250.20 11 205 4.9E-26 T 23-10-2018 TON_1179 12ca2e6d0b67cb420c619db9d2dd2ef0 546 Gene3D G3DSA:3.40.50.300 265 542 3.3E-90 T 23-10-2018 TON_1179 12ca2e6d0b67cb420c619db9d2dd2ef0 546 Gene3D G3DSA:3.30.450.370 49 262 3.9E-57 T 23-10-2018 TON_1179 12ca2e6d0b67cb420c619db9d2dd2ef0 546 Pfam PF00437 Type II/IV secretion system protein 167 412 8.0E-48 T 23-10-2018 IPR001482 Type II/IV secretion system protein TON_1179 12ca2e6d0b67cb420c619db9d2dd2ef0 546 SUPERFAMILY SSF52540 147 529 1.5E-57 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_1179 12ca2e6d0b67cb420c619db9d2dd2ef0 546 Gene3D G3DSA:1.10.390.40 82 164 3.9E-57 T 23-10-2018 TON_1877 a63e648166d8f73c9f0c9a42f8cd4d60 544 SUPERFAMILY SSF52029 212 378 1.63E-62 T 23-10-2018 IPR027409 GroEL-like apical domain superfamily TON_1877 a63e648166d8f73c9f0c9a42f8cd4d60 544 ProSitePatterns PS00750 Chaperonins TCP-1 signature 1. 40 52 - T 23-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 TON_1877 a63e648166d8f73c9f0c9a42f8cd4d60 544 SUPERFAMILY SSF48592 17 524 3.21E-92 T 23-10-2018 IPR027413 GroEL-like equatorial domain superfamily TON_1877 a63e648166d8f73c9f0c9a42f8cd4d60 544 Gene3D G3DSA:3.50.7.10 218 369 3.6E-212 T 23-10-2018 IPR027409 GroEL-like apical domain superfamily TON_1877 a63e648166d8f73c9f0c9a42f8cd4d60 544 SUPERFAMILY SSF54849 147 405 3.02E-29 T 23-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily TON_1877 a63e648166d8f73c9f0c9a42f8cd4d60 544 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 59 77 2.0E-34 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 TON_1877 a63e648166d8f73c9f0c9a42f8cd4d60 544 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 373 395 2.0E-34 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 TON_1877 a63e648166d8f73c9f0c9a42f8cd4d60 544 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 407 419 2.0E-34 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 TON_1877 a63e648166d8f73c9f0c9a42f8cd4d60 544 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 37 53 2.0E-34 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 TON_1877 a63e648166d8f73c9f0c9a42f8cd4d60 544 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 89 108 2.0E-34 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 TON_1877 a63e648166d8f73c9f0c9a42f8cd4d60 544 ProSitePatterns PS00995 Chaperonins TCP-1 signature 3. 89 97 - T 23-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 TON_1877 a63e648166d8f73c9f0c9a42f8cd4d60 544 ProSitePatterns PS00751 Chaperonins TCP-1 signature 2. 61 77 - T 23-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 TON_1877 a63e648166d8f73c9f0c9a42f8cd4d60 544 Gene3D G3DSA:3.30.260.10 147 405 3.6E-212 T 23-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily TON_1877 a63e648166d8f73c9f0c9a42f8cd4d60 544 Gene3D G3DSA:1.10.560.10 28 522 3.6E-212 T 23-10-2018 IPR027413 GroEL-like equatorial domain superfamily TON_1877 a63e648166d8f73c9f0c9a42f8cd4d60 544 TIGRFAM TIGR02339 thermosome_arch: thermosome, various subunits, archaeal 8 524 3.9E-243 T 23-10-2018 IPR012714 Thermosome, archaeal GO:0005524|GO:0006457|GO:0051082 TON_1877 a63e648166d8f73c9f0c9a42f8cd4d60 544 Pfam PF00118 TCP-1/cpn60 chaperonin family 35 525 2.4E-181 T 23-10-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 TON_0348 436c72b505ec08eccf18c0e2c401bd48 382 Gene3D G3DSA:3.30.70.360 176 290 1.0E-145 T 23-10-2018 TON_0348 436c72b505ec08eccf18c0e2c401bd48 382 SUPERFAMILY SSF55031 177 285 1.96E-32 T 23-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain TON_0348 436c72b505ec08eccf18c0e2c401bd48 382 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 14 368 2.3E-121 T 23-10-2018 IPR017439 Amidohydrolase GO:0016787 TON_0348 436c72b505ec08eccf18c0e2c401bd48 382 Gene3D G3DSA:3.40.630.10 14 365 1.0E-145 T 23-10-2018 TON_0348 436c72b505ec08eccf18c0e2c401bd48 382 SUPERFAMILY SSF53187 5 381 1.29E-87 T 23-10-2018 TON_0348 436c72b505ec08eccf18c0e2c401bd48 382 PIRSF PIRSF005962 1 382 2.9E-135 T 23-10-2018 IPR017439 Amidohydrolase GO:0016787 TON_0348 436c72b505ec08eccf18c0e2c401bd48 382 Pfam PF07687 Peptidase dimerisation domain 177 276 6.8E-14 T 23-10-2018 IPR011650 Peptidase M20, dimerisation domain TON_0348 436c72b505ec08eccf18c0e2c401bd48 382 Pfam PF01546 Peptidase family M20/M25/M40 68 371 1.6E-36 T 23-10-2018 IPR002933 Peptidase M20 GO:0016787 TON_0318 33403b05126fd70832e6dd6238ad1e43 236 Pfam PF12840 Helix-turn-helix domain 5 59 2.2E-8 T 23-10-2018 TON_0318 33403b05126fd70832e6dd6238ad1e43 236 Gene3D G3DSA:1.10.10.10 164 232 1.8E-37 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TON_0318 33403b05126fd70832e6dd6238ad1e43 236 Gene3D G3DSA:1.10.10.10 2 77 1.6E-20 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TON_0318 33403b05126fd70832e6dd6238ad1e43 236 SMART SM00418 5 86 5.5E-11 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TON_0318 33403b05126fd70832e6dd6238ad1e43 236 SUPERFAMILY SSF46785 5 93 4.68E-14 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TON_0507 c39a631c0abfaade958fdcc5170454d4 415 Pfam PF03464 eRF1 domain 2 140 272 3.5E-49 T 23-10-2018 IPR005141 eRF1 domain 2 TON_0507 c39a631c0abfaade958fdcc5170454d4 415 Pfam PF03463 eRF1 domain 1 17 133 3.6E-9 T 23-10-2018 IPR005140 eRF1 domain 1/Pelota-like TON_0507 c39a631c0abfaade958fdcc5170454d4 415 SUPERFAMILY SSF55315 273 414 1.88E-41 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like TON_0507 c39a631c0abfaade958fdcc5170454d4 415 Hamap MF_00424 Peptide chain release factor subunit 1 [prf1]. 18 415 45.542 T 23-10-2018 IPR020918 Peptide chain release factor aRF1 GO:0003747|GO:0005737|GO:0006415 TON_0507 c39a631c0abfaade958fdcc5170454d4 415 Gene3D G3DSA:3.30.420.60 131 271 4.1E-54 T 23-10-2018 TON_0507 c39a631c0abfaade958fdcc5170454d4 415 SMART SM01194 1 135 2.9E-34 T 23-10-2018 IPR005140 eRF1 domain 1/Pelota-like TON_0507 c39a631c0abfaade958fdcc5170454d4 415 SUPERFAMILY SSF55481 3 135 1.14E-48 T 23-10-2018 IPR024049 Peptide Chain Release Factor eRF1/aRF1, N-terminal Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0507 c39a631c0abfaade958fdcc5170454d4 415 Pfam PF03465 eRF1 domain 3 276 414 5.3E-35 T 23-10-2018 IPR005142 eRF1 domain 3 TON_0507 c39a631c0abfaade958fdcc5170454d4 415 TIGRFAM TIGR03676 aRF1/eRF1: peptide chain release factor 1, archaeal and eukaryotic forms 7 414 1.3E-181 T 23-10-2018 IPR004403 Peptide chain release factor eRF1/aRF1 GO:0003747|GO:0005737|GO:0006415 Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0507 c39a631c0abfaade958fdcc5170454d4 415 SUPERFAMILY SSF53137 138 270 1.48E-43 T 23-10-2018 TON_0507 c39a631c0abfaade958fdcc5170454d4 415 Gene3D G3DSA:3.30.1330.30 274 415 2.3E-44 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like TON_0507 c39a631c0abfaade958fdcc5170454d4 415 Gene3D G3DSA:3.30.960.10 1 130 1.1E-54 T 23-10-2018 IPR024049 Peptide Chain Release Factor eRF1/aRF1, N-terminal Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0770 f612b880e0e6d26f5b66424267471fcd 227 Pfam PF01351 Ribonuclease HII 4 200 1.8E-51 T 23-10-2018 IPR024567 Ribonuclease HII/HIII domain TON_0770 f612b880e0e6d26f5b66424267471fcd 227 Gene3D G3DSA:3.30.420.10 2 161 1.4E-59 T 23-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 TON_0770 f612b880e0e6d26f5b66424267471fcd 227 TIGRFAM TIGR00729 TIGR00729: ribonuclease HII 4 205 6.9E-78 T 23-10-2018 IPR004649 Ribonuclease H2, subunit A GO:0004523|GO:0016070 TON_0770 f612b880e0e6d26f5b66424267471fcd 227 Hamap MF_00052_A Ribonuclease HII [rnhB]. 2 206 38.19 T 23-10-2018 IPR020787 Ribonuclease HII, archaea GO:0004523|GO:0005737|GO:0006401|GO:0030145 TON_0770 f612b880e0e6d26f5b66424267471fcd 227 Gene3D G3DSA:1.10.10.460 162 208 4.8E-25 T 23-10-2018 IPR023160 Ribonuclease HII, helix-loop-helix cap domain superfamily GO:0004523 TON_0770 f612b880e0e6d26f5b66424267471fcd 227 SUPERFAMILY SSF53098 3 209 1.82E-60 T 23-10-2018 IPR012337 Ribonuclease H-like superfamily TON_0625 b27111875ecbfc2e8255f7aa4a34f889 327 SUPERFAMILY SSF117892 75 203 4.97E-13 T 23-10-2018 IPR036013 Band 7/SPFH domain superfamily TON_0625 b27111875ecbfc2e8255f7aa4a34f889 327 Pfam PF12773 Double zinc ribbon 282 323 4.3E-10 T 23-10-2018 IPR025874 Double zinc ribbon TON_0625 b27111875ecbfc2e8255f7aa4a34f889 327 Pfam PF13421 SPFH domain-Band 7 family 16 204 5.1E-35 T 23-10-2018 IPR033880 SPFH domain, YdjI-like TON_0218 a4ce878f55112502f4c222bd91d8cad9 905 Pfam PF04998 RNA polymerase Rpb1, domain 5 811 876 4.1E-29 T 23-10-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TON_0218 a4ce878f55112502f4c222bd91d8cad9 905 SMART SM00663 211 515 4.6E-207 T 23-10-2018 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TON_0218 a4ce878f55112502f4c222bd91d8cad9 905 Pfam PF00623 RNA polymerase Rpb1, domain 2 321 487 2.6E-74 T 23-10-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TON_0218 a4ce878f55112502f4c222bd91d8cad9 905 Gene3D G3DSA:1.10.274.100 491 671 9.2E-64 T 23-10-2018 TON_0218 a4ce878f55112502f4c222bd91d8cad9 905 Gene3D G3DSA:3.30.1490.180 354 418 6.3E-81 T 23-10-2018 TON_0218 a4ce878f55112502f4c222bd91d8cad9 905 Pfam PF04997 RNA polymerase Rpb1, domain 1 6 319 2.5E-106 T 23-10-2018 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TON_0218 a4ce878f55112502f4c222bd91d8cad9 905 SUPERFAMILY SSF64484 4 887 0.0 T 23-10-2018 TON_0218 a4ce878f55112502f4c222bd91d8cad9 905 Pfam PF05000 RNA polymerase Rpb1, domain 4 699 804 7.6E-31 T 23-10-2018 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TON_0218 a4ce878f55112502f4c222bd91d8cad9 905 Gene3D G3DSA:1.20.120.1280 1 121 1.4E-30 T 23-10-2018 TON_0218 a4ce878f55112502f4c222bd91d8cad9 905 Gene3D G3DSA:1.20.120.1280 235 284 2.2E-11 T 23-10-2018 TON_0218 a4ce878f55112502f4c222bd91d8cad9 905 TIGRFAM TIGR02390 RNA_pol_rpoA1: DNA-directed RNA polymerase subunit A' 5 894 0.0 T 23-10-2018 IPR012758 DNA-directed RNA polymerase subunit A' (Rpo1N) GO:0003677|GO:0003899|GO:0006351|GO:0008270 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TON_0218 a4ce878f55112502f4c222bd91d8cad9 905 Gene3D G3DSA:1.10.132.30 672 813 8.1E-44 T 23-10-2018 IPR038120 RNA polymerase Rpb1, funnel domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TON_0218 a4ce878f55112502f4c222bd91d8cad9 905 Gene3D G3DSA:2.20.25.410 850 900 2.3E-22 T 23-10-2018 TON_0218 a4ce878f55112502f4c222bd91d8cad9 905 Pfam PF04983 RNA polymerase Rpb1, domain 3 490 672 7.1E-37 T 23-10-2018 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TON_0218 a4ce878f55112502f4c222bd91d8cad9 905 Gene3D G3DSA:2.40.40.20 311 482 6.3E-81 T 23-10-2018 TON_1625 7f1c34af1109f9a0c2cf6bd3677e553d 173 Gene3D G3DSA:1.10.10.10 2 86 9.5E-24 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TON_1625 7f1c34af1109f9a0c2cf6bd3677e553d 173 Pfam PF01047 MarR family 39 81 4.9E-8 T 23-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TON_1625 7f1c34af1109f9a0c2cf6bd3677e553d 173 PIRSF PIRSF006707 1 173 2.4E-39 T 23-10-2018 IPR026282 DNA-binding protein, MJ1563 type TON_1625 7f1c34af1109f9a0c2cf6bd3677e553d 173 SMART SM00347 16 110 0.0035 T 23-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TON_1625 7f1c34af1109f9a0c2cf6bd3677e553d 173 SUPERFAMILY SSF46785 3 136 6.41E-21 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TON_0319 d1a9dd96d08f0cf4f14b37f872ac6889 226 SUPERFAMILY SSF52833 120 221 5.74E-21 T 23-10-2018 IPR036249 Thioredoxin-like superfamily TON_0319 d1a9dd96d08f0cf4f14b37f872ac6889 226 TIGRFAM TIGR02187 GlrX_arch: glutaredoxin-like domain protein 4 223 1.2E-86 T 23-10-2018 IPR011903 Glutaredoxin-like domain TON_0319 d1a9dd96d08f0cf4f14b37f872ac6889 226 Pfam PF13192 Thioredoxin domain 137 222 5.7E-15 T 23-10-2018 IPR012336 Thioredoxin-like fold TON_0319 d1a9dd96d08f0cf4f14b37f872ac6889 226 SUPERFAMILY SSF52833 6 117 1.53E-25 T 23-10-2018 IPR036249 Thioredoxin-like superfamily TON_0319 d1a9dd96d08f0cf4f14b37f872ac6889 226 Gene3D G3DSA:3.40.30.10 120 225 4.3E-27 T 23-10-2018 TON_0319 d1a9dd96d08f0cf4f14b37f872ac6889 226 Gene3D G3DSA:3.40.30.10 1 117 7.0E-37 T 23-10-2018 TON_0578 6f4030888fdca2a437af7070b108fd0d 317 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 250 308 1.5E-8 T 23-10-2018 IPR002831 Transcription regulator TrmB, N-terminal TON_0578 6f4030888fdca2a437af7070b108fd0d 317 Gene3D G3DSA:1.10.10.10 238 315 2.0E-10 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TON_0578 6f4030888fdca2a437af7070b108fd0d 317 SUPERFAMILY SSF46785 245 309 3.08E-12 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TON_1263 a4b863a404c7e7758be27644b0364996 239 TIGRFAM TIGR00364 TIGR00364: queuosine biosynthesis protein QueC 4 218 1.7E-48 T 23-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 TON_1263 a4b863a404c7e7758be27644b0364996 239 Gene3D G3DSA:3.40.50.620 1 237 6.7E-61 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TON_1263 a4b863a404c7e7758be27644b0364996 239 Pfam PF06508 Queuosine biosynthesis protein QueC 3 225 1.4E-63 T 23-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 TON_1263 a4b863a404c7e7758be27644b0364996 239 PIRSF PIRSF006293 1 238 2.5E-69 T 23-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 TON_1263 a4b863a404c7e7758be27644b0364996 239 SUPERFAMILY SSF52402 1 235 7.72E-51 T 23-10-2018 TON_1263 a4b863a404c7e7758be27644b0364996 239 Hamap MF_01633 7-cyano-7-deazaguanine synthase [queC]. 2 231 46.226 T 23-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 TON_0892 19b413dc620dc44973e5ab81e0871dcf 237 PIRSF PIRSF005054 1 237 8.1E-38 T 23-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 TON_0892 19b413dc620dc44973e5ab81e0871dcf 237 Gene3D G3DSA:3.30.70.1900 105 234 2.9E-11 T 23-10-2018 TON_0892 19b413dc620dc44973e5ab81e0871dcf 237 Pfam PF01881 CRISPR associated protein Cas6 81 233 1.4E-20 T 23-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 TON_0892 19b413dc620dc44973e5ab81e0871dcf 237 TIGRFAM TIGR01877 cas_cas6: CRISPR-associated endoribonuclease Cas6 39 233 9.3E-32 T 23-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 TON_0892 19b413dc620dc44973e5ab81e0871dcf 237 Gene3D G3DSA:3.30.70.1890 14 104 1.3E-6 T 23-10-2018 TON_1021 a2496c483538e1751897be4f41228637 634 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 315 327 1.5E-8 T 23-10-2018 TON_1021 a2496c483538e1751897be4f41228637 634 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 224 245 1.5E-8 T 23-10-2018 TON_1021 a2496c483538e1751897be4f41228637 634 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 80 105 1.5E-8 T 23-10-2018 TON_1021 a2496c483538e1751897be4f41228637 634 Pfam PF00361 Proton-conducting membrane transporter 133 419 6.4E-58 T 23-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_0602 282c18acfdaac1b4f0ae4ad7e437bdc9 476 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 16 314 1.1E-137 T 23-10-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 TON_0602 282c18acfdaac1b4f0ae4ad7e437bdc9 476 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 4 473 1.6E-181 T 23-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 TON_0602 282c18acfdaac1b4f0ae4ad7e437bdc9 476 SUPERFAMILY SSF52374 4 314 2.3E-111 T 23-10-2018 TON_0602 282c18acfdaac1b4f0ae4ad7e437bdc9 476 SMART SM00840 356 417 9.5E-15 T 23-10-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 TON_0602 282c18acfdaac1b4f0ae4ad7e437bdc9 476 Gene3D G3DSA:1.20.120.640 306 473 1.2E-38 T 23-10-2018 TON_0602 282c18acfdaac1b4f0ae4ad7e437bdc9 476 SUPERFAMILY SSF47323 316 473 1.31E-35 T 23-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 TON_0602 282c18acfdaac1b4f0ae4ad7e437bdc9 476 Pfam PF09190 DALR domain 356 415 2.6E-16 T 23-10-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 TON_0602 282c18acfdaac1b4f0ae4ad7e437bdc9 476 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 3 474 40.009 T 23-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 TON_0602 282c18acfdaac1b4f0ae4ad7e437bdc9 476 Gene3D G3DSA:3.40.50.620 1 305 1.2E-149 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TON_0602 282c18acfdaac1b4f0ae4ad7e437bdc9 476 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 222 243 2.0E-30 T 23-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 TON_0602 282c18acfdaac1b4f0ae4ad7e437bdc9 476 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 191 209 2.0E-30 T 23-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 TON_0602 282c18acfdaac1b4f0ae4ad7e437bdc9 476 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 26 37 2.0E-30 T 23-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 TON_0602 282c18acfdaac1b4f0ae4ad7e437bdc9 476 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 62 71 2.0E-30 T 23-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 TON_0691 9907f3a5a263fa3adb87aa9f0038ad5e 396 Pfam PF03453 MoeA N-terminal region (domain I and II) 9 173 1.4E-47 T 23-10-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TON_0691 9907f3a5a263fa3adb87aa9f0038ad5e 396 Pfam PF03454 MoeA C-terminal region (domain IV) 330 395 1.2E-17 T 23-10-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TON_0691 9907f3a5a263fa3adb87aa9f0038ad5e 396 SUPERFAMILY SSF63882 7 182 5.76E-59 T 23-10-2018 IPR036135 MoeA, N-terminal and linker domain superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TON_0691 9907f3a5a263fa3adb87aa9f0038ad5e 396 SUPERFAMILY SSF63867 327 396 1.7E-19 T 23-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TON_0691 9907f3a5a263fa3adb87aa9f0038ad5e 396 Gene3D G3DSA:2.170.190.11 50 148 2.2E-111 T 23-10-2018 TON_0691 9907f3a5a263fa3adb87aa9f0038ad5e 396 Pfam PF00994 Probable molybdopterin binding domain 186 315 1.1E-18 T 23-10-2018 IPR001453 MoaB/Mog domain TON_0691 9907f3a5a263fa3adb87aa9f0038ad5e 396 SUPERFAMILY SSF53218 181 321 4.45E-35 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily TON_0691 9907f3a5a263fa3adb87aa9f0038ad5e 396 Gene3D G3DSA:3.40.980.10 20 314 2.2E-111 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily TON_0691 9907f3a5a263fa3adb87aa9f0038ad5e 396 SMART SM00852 186 317 5.5E-30 T 23-10-2018 IPR001453 MoaB/Mog domain TON_0691 9907f3a5a263fa3adb87aa9f0038ad5e 396 Gene3D G3DSA:2.40.340.10 320 396 3.1E-27 T 23-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TON_0691 9907f3a5a263fa3adb87aa9f0038ad5e 396 Gene3D G3DSA:3.90.105.10 27 181 2.2E-111 T 23-10-2018 TON_0170 cd47faecac4e0a2d2698399fd2c81605 402 SUPERFAMILY SSF53743 1 281 1.57E-38 T 23-10-2018 IPR009015 L-fucose isomerase, N-terminal/central domain superfamily GO:0005737|GO:0005996|GO:0016861 TON_1268 a15867f43cf9bbb151bcabec8eff7fda 388 Pfam PF01266 FAD dependent oxidoreductase 3 354 1.9E-74 T 23-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 TON_1268 a15867f43cf9bbb151bcabec8eff7fda 388 SUPERFAMILY SSF54373 225 318 2.06E-8 T 23-10-2018 TON_1268 a15867f43cf9bbb151bcabec8eff7fda 388 Gene3D G3DSA:3.50.50.60 4 360 2.1E-116 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TON_1268 a15867f43cf9bbb151bcabec8eff7fda 388 SUPERFAMILY SSF51905 2 378 3.75E-58 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TON_1268 a15867f43cf9bbb151bcabec8eff7fda 388 Gene3D G3DSA:3.30.9.10 82 317 2.1E-116 T 23-10-2018 TON_0886 6db32a5f2da0022c97d7889e8fda1c98 335 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 2 331 53.411 T 23-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 TON_0886 6db32a5f2da0022c97d7889e8fda1c98 335 Gene3D G3DSA:3.40.640.10 44 247 6.4E-102 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TON_0886 6db32a5f2da0022c97d7889e8fda1c98 335 SUPERFAMILY SSF53383 14 332 7.18E-79 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TON_0886 6db32a5f2da0022c97d7889e8fda1c98 335 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 5 329 2.8E-100 T 23-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 TON_0886 6db32a5f2da0022c97d7889e8fda1c98 335 Pfam PF00155 Aminotransferase class I and II 22 327 3.0E-51 T 23-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 TON_0886 6db32a5f2da0022c97d7889e8fda1c98 335 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 200 209 - T 23-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 TON_0886 6db32a5f2da0022c97d7889e8fda1c98 335 Gene3D G3DSA:3.90.1150.10 24 324 6.4E-102 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TON_0643 f90207f49f15e1a12f0b81811692faa8 567 Hamap MF_00253_A Glycine--tRNA ligase [glyQS]. 3 565 46.742 T 23-10-2018 IPR022960 Glycine-tRNA ligase, archaeal GO:0004820 KEGG: 00970+6.1.1.14 TON_0643 f90207f49f15e1a12f0b81811692faa8 567 SUPERFAMILY SSF55681 3 475 4.15E-117 T 23-10-2018 TON_0643 f90207f49f15e1a12f0b81811692faa8 567 SUPERFAMILY SSF52954 459 564 1.66E-33 T 23-10-2018 TON_0643 f90207f49f15e1a12f0b81811692faa8 567 PRINTS PR01043 Glycyl-tRNA synthetase signature 190 207 1.2E-56 T 23-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 TON_0643 f90207f49f15e1a12f0b81811692faa8 567 PRINTS PR01043 Glycyl-tRNA synthetase signature 24 38 1.2E-56 T 23-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 TON_0643 f90207f49f15e1a12f0b81811692faa8 567 PRINTS PR01043 Glycyl-tRNA synthetase signature 158 175 1.2E-56 T 23-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 TON_0643 f90207f49f15e1a12f0b81811692faa8 567 PRINTS PR01043 Glycyl-tRNA synthetase signature 510 529 1.2E-56 T 23-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 TON_0643 f90207f49f15e1a12f0b81811692faa8 567 PRINTS PR01043 Glycyl-tRNA synthetase signature 139 151 1.2E-56 T 23-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 TON_0643 f90207f49f15e1a12f0b81811692faa8 567 PRINTS PR01043 Glycyl-tRNA synthetase signature 207 217 1.2E-56 T 23-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 TON_0643 f90207f49f15e1a12f0b81811692faa8 567 PRINTS PR01043 Glycyl-tRNA synthetase signature 432 444 1.2E-56 T 23-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 TON_0643 f90207f49f15e1a12f0b81811692faa8 567 Gene3D G3DSA:1.10.30.30 360 423 8.6E-142 T 23-10-2018 TON_0643 f90207f49f15e1a12f0b81811692faa8 567 Pfam PF03129 Anticodon binding domain 472 562 4.4E-24 T 23-10-2018 IPR004154 Anticodon-binding TON_0643 f90207f49f15e1a12f0b81811692faa8 567 TIGRFAM TIGR00389 glyS_dimeric: glycine--tRNA ligase 5 562 2.1E-217 T 23-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 TON_0643 f90207f49f15e1a12f0b81811692faa8 567 Gene3D G3DSA:1.20.1430.20 81 144 8.6E-142 T 23-10-2018 TON_0643 f90207f49f15e1a12f0b81811692faa8 567 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 155 232 1.3E-10 T 23-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 TON_0643 f90207f49f15e1a12f0b81811692faa8 567 Gene3D G3DSA:3.30.930.10 11 455 8.6E-142 T 23-10-2018 TON_0643 f90207f49f15e1a12f0b81811692faa8 567 Gene3D G3DSA:3.40.50.800 470 567 8.2E-33 T 23-10-2018 IPR036621 Anticodon-binding domain superfamily TON_0666 b2d504ad3a5ea756a238bba09e1d17c4 397 Pfam PF01926 50S ribosome-binding GTPase 2 121 9.8E-20 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 TON_0666 b2d504ad3a5ea756a238bba09e1d17c4 397 Gene3D G3DSA:3.10.20.30 319 397 1.5E-30 T 23-10-2018 IPR012675 Beta-grasp domain superfamily TON_0666 b2d504ad3a5ea756a238bba09e1d17c4 397 Gene3D G3DSA:1.10.8.470 126 215 3.5E-30 T 23-10-2018 TON_0666 b2d504ad3a5ea756a238bba09e1d17c4 397 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 92 110 4.4E-31 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 TON_0666 b2d504ad3a5ea756a238bba09e1d17c4 397 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 3 23 4.4E-31 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 TON_0666 b2d504ad3a5ea756a238bba09e1d17c4 397 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 75 90 4.4E-31 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 TON_0666 b2d504ad3a5ea756a238bba09e1d17c4 397 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 24 42 4.4E-31 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 TON_0666 b2d504ad3a5ea756a238bba09e1d17c4 397 SUPERFAMILY SSF52540 1 315 4.42E-71 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_0666 b2d504ad3a5ea756a238bba09e1d17c4 397 Pfam PF02824 TGS domain 341 393 6.2E-13 T 23-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 TON_0666 b2d504ad3a5ea756a238bba09e1d17c4 397 SUPERFAMILY SSF81271 323 393 3.4E-18 T 23-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 TON_0666 b2d504ad3a5ea756a238bba09e1d17c4 397 Pfam PF08438 GTPase of unknown function C-terminal 220 327 2.0E-36 T 23-10-2018 IPR013646 Uncharacterised GTP-binding protein, C-terminal TON_0043 a0db671c4e54c5305e6077079e32a7f4 1157 Gene3D G3DSA:1.10.10.10 1072 1157 1.5E-22 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TON_0043 a0db671c4e54c5305e6077079e32a7f4 1157 Pfam PF14528 LAGLIDADG-like domain 592 673 1.5E-21 T 23-10-2018 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 TON_0043 a0db671c4e54c5305e6077079e32a7f4 1157 Pfam PF14528 LAGLIDADG-like domain 496 568 7.9E-6 T 23-10-2018 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 TON_0043 a0db671c4e54c5305e6077079e32a7f4 1157 SMART SM00305 768 815 2.2E-15 T 23-10-2018 IPR003586 Hint domain C-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TON_0043 a0db671c4e54c5305e6077079e32a7f4 1157 Gene3D G3DSA:1.10.260.40 701 752 1.3E-5 T 23-10-2018 TON_0043 a0db671c4e54c5305e6077079e32a7f4 1157 SMART SM00350 101 1068 6.4E-134 T 23-10-2018 IPR031327 Mini-chromosome maintenance protein TON_0043 a0db671c4e54c5305e6077079e32a7f4 1157 Gene3D G3DSA:2.170.16.10 336 491 4.7E-36 T 23-10-2018 TON_0043 a0db671c4e54c5305e6077079e32a7f4 1157 SUPERFAMILY SSF51294 335 809 1.96E-42 T 23-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TON_0043 a0db671c4e54c5305e6077079e32a7f4 1157 Pfam PF17207 MCM OB domain 105 230 6.3E-36 T 23-10-2018 IPR033762 MCM OB domain Reactome: R-HSA-176187|Reactome: R-HSA-176974|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962 TON_0043 a0db671c4e54c5305e6077079e32a7f4 1157 Gene3D G3DSA:2.20.28.10 132 176 2.1E-28 T 23-10-2018 TON_0043 a0db671c4e54c5305e6077079e32a7f4 1157 Gene3D G3DSA:2.40.50.140 177 257 3.3E-27 T 23-10-2018 TON_0043 a0db671c4e54c5305e6077079e32a7f4 1157 Pfam PF14890 Intein splicing domain 343 809 1.4E-43 T 23-10-2018 TON_0043 a0db671c4e54c5305e6077079e32a7f4 1157 SUPERFAMILY SSF52540 810 1064 3.16E-39 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_0043 a0db671c4e54c5305e6077079e32a7f4 1157 SMART SM00530 705 756 1.6E-5 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TON_0043 a0db671c4e54c5305e6077079e32a7f4 1157 SUPERFAMILY SSF47413 702 750 6.22E-7 T 23-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TON_0043 a0db671c4e54c5305e6077079e32a7f4 1157 TIGRFAM TIGR01445 intein_Nterm: intein N-terminal splicing region 336 433 8.0E-20 T 23-10-2018 IPR006141 Intein N-terminal splicing region GO:0016539 Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TON_0043 a0db671c4e54c5305e6077079e32a7f4 1157 Pfam PF14551 MCM N-terminal domain 8 82 2.4E-11 T 23-10-2018 IPR027925 MCM N-terminal domain Reactome: R-HSA-176187|Reactome: R-HSA-176974|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962|Reactome: R-HSA-69052 TON_0043 a0db671c4e54c5305e6077079e32a7f4 1157 Gene3D G3DSA:3.40.50.300 263 335 2.1E-23 T 23-10-2018 TON_0043 a0db671c4e54c5305e6077079e32a7f4 1157 Gene3D G3DSA:3.40.50.300 793 1071 1.7E-112 T 23-10-2018 TON_0043 a0db671c4e54c5305e6077079e32a7f4 1157 Gene3D G3DSA:3.30.1640.10 1 100 1.1E-36 T 23-10-2018 TON_0043 a0db671c4e54c5305e6077079e32a7f4 1157 Gene3D G3DSA:3.10.28.10 492 670 2.9E-35 T 23-10-2018 IPR027434 Homing endonuclease TON_0043 a0db671c4e54c5305e6077079e32a7f4 1157 SUPERFAMILY SSF55608 575 686 1.11E-19 T 23-10-2018 IPR027434 Homing endonuclease TON_0043 a0db671c4e54c5305e6077079e32a7f4 1157 SUPERFAMILY SSF55608 493 564 4.46E-7 T 23-10-2018 IPR027434 Homing endonuclease TON_0043 a0db671c4e54c5305e6077079e32a7f4 1157 SUPERFAMILY SSF50249 10 248 4.11E-62 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold TON_0043 a0db671c4e54c5305e6077079e32a7f4 1157 Pfam PF00493 MCM2/3/5 family 803 1067 6.0E-107 T 23-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 TON_0043 a0db671c4e54c5305e6077079e32a7f4 1157 Pfam PF00493 MCM2/3/5 family 266 336 2.6E-22 T 23-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 TON_0043 a0db671c4e54c5305e6077079e32a7f4 1157 Pfam PF01381 Helix-turn-helix 706 753 5.9E-7 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TON_0043 a0db671c4e54c5305e6077079e32a7f4 1157 SMART SM00306 334 457 6.4E-29 T 23-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TON_0043 a0db671c4e54c5305e6077079e32a7f4 1157 PRINTS PR00379 Intein signature 786 803 1.2E-21 T 23-10-2018 IPR006142 Intein GO:0016539 TON_0043 a0db671c4e54c5305e6077079e32a7f4 1157 PRINTS PR00379 Intein signature 592 604 1.2E-21 T 23-10-2018 IPR006142 Intein GO:0016539 TON_0043 a0db671c4e54c5305e6077079e32a7f4 1157 PRINTS PR00379 Intein signature 493 505 1.2E-21 T 23-10-2018 IPR006142 Intein GO:0016539 TON_0043 a0db671c4e54c5305e6077079e32a7f4 1157 PRINTS PR00379 Intein signature 620 635 1.2E-21 T 23-10-2018 IPR006142 Intein GO:0016539 TON_0043 a0db671c4e54c5305e6077079e32a7f4 1157 PRINTS PR00379 Intein signature 804 813 1.2E-21 T 23-10-2018 IPR006142 Intein GO:0016539 TON_0043 a0db671c4e54c5305e6077079e32a7f4 1157 PRINTS PR00379 Intein signature 420 433 1.2E-21 T 23-10-2018 IPR006142 Intein GO:0016539 TON_0043 a0db671c4e54c5305e6077079e32a7f4 1157 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 788 810 6.7E-9 T 23-10-2018 IPR030934 Intein C-terminal splicing region TON_1938 5e0a36b78bbb7fb767e5ae53a9d6da4a 442 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 226 240 1.7E-23 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TON_1938 5e0a36b78bbb7fb767e5ae53a9d6da4a 442 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 422 439 1.7E-23 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TON_1938 5e0a36b78bbb7fb767e5ae53a9d6da4a 442 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 255 265 1.7E-23 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TON_1938 5e0a36b78bbb7fb767e5ae53a9d6da4a 442 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 323 335 1.7E-23 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TON_1938 5e0a36b78bbb7fb767e5ae53a9d6da4a 442 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 373 389 1.7E-23 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TON_1938 5e0a36b78bbb7fb767e5ae53a9d6da4a 442 Gene3D G3DSA:3.40.50.150 149 439 6.4E-90 T 23-10-2018 TON_1938 5e0a36b78bbb7fb767e5ae53a9d6da4a 442 SUPERFAMILY SSF53335 147 440 1.86E-76 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TON_1938 5e0a36b78bbb7fb767e5ae53a9d6da4a 442 Pfam PF17125 N-terminal domain of 16S rRNA methyltransferase RsmF 152 238 4.5E-9 T 23-10-2018 IPR031341 Ribosomal RNA small subunit methyltransferase F, N-terminal Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 TON_1938 5e0a36b78bbb7fb767e5ae53a9d6da4a 442 Pfam PF01189 16S rRNA methyltransferase RsmB/F 244 437 1.2E-64 T 23-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 TON_1938 5e0a36b78bbb7fb767e5ae53a9d6da4a 442 Gene3D G3DSA:1.10.940.10 2 148 2.9E-39 T 23-10-2018 IPR035926 NusB-like superfamily TON_0192 9d8988670807b3c483c0dde1562f8da1 625 Pfam PF17297 Phosphoenolpyruvate carboxykinase N-terminal domain 29 239 7.5E-56 T 23-10-2018 IPR035078 Phosphoenolpyruvate carboxykinase, GTP-utilising, N-terminal GO:0004611|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 TON_0192 9d8988670807b3c483c0dde1562f8da1 625 PIRSF PIRSF001348 5 610 2.1E-208 T 23-10-2018 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 TON_0192 9d8988670807b3c483c0dde1562f8da1 625 Pfam PF00821 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain 244 606 6.2E-106 T 23-10-2018 IPR035077 Phosphoenolpyruvate carboxykinase, GTP-utilising, C-terminal GO:0004611|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 TON_0192 9d8988670807b3c483c0dde1562f8da1 625 Gene3D G3DSA:3.90.228.20 247 605 5.9E-146 T 23-10-2018 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 TON_0192 9d8988670807b3c483c0dde1562f8da1 625 SUPERFAMILY SSF68923 11 243 2.41E-60 T 23-10-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 TON_0192 9d8988670807b3c483c0dde1562f8da1 625 SUPERFAMILY SSF53795 244 606 8.7E-107 T 23-10-2018 TON_0192 9d8988670807b3c483c0dde1562f8da1 625 Hamap MF_00452 Phosphoenolpyruvate carboxykinase [GTP] [pckG]. 18 607 35.707 T 23-10-2018 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 TON_0192 9d8988670807b3c483c0dde1562f8da1 625 ProSitePatterns PS00505 Phosphoenolpyruvate carboxykinase (GTP) signature. 268 276 - T 23-10-2018 IPR018091 Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site GO:0004613 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 TON_0192 9d8988670807b3c483c0dde1562f8da1 625 Gene3D G3DSA:2.170.8.10 65 398 5.9E-146 T 23-10-2018 TON_0192 9d8988670807b3c483c0dde1562f8da1 625 Gene3D G3DSA:3.40.449.10 27 246 5.9E-146 T 23-10-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 TON_1581 737cf99bc1b1725aa70c7e93c38564f6 195 SUPERFAMILY SSF53448 2 185 6.53E-30 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TON_1581 737cf99bc1b1725aa70c7e93c38564f6 195 Gene3D G3DSA:3.90.550.10 4 190 2.1E-43 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TON_1581 737cf99bc1b1725aa70c7e93c38564f6 195 Pfam PF12804 MobA-like NTP transferase domain 3 134 1.3E-29 T 23-10-2018 IPR025877 MobA-like NTP transferase TON_1581 737cf99bc1b1725aa70c7e93c38564f6 195 Hamap MF_00316 Molybdenum cofactor guanylyltransferase [mobA]. 1 188 20.241 T 23-10-2018 IPR013482 Molybdenum cofactor guanylyltransferase GO:0003824|GO:0006777 KEGG: 00790+2.7.7.77|MetaCyc: PWY-5964|MetaCyc: PWY-7639 TON_0925 d4d5267981664ee37ce5a100f8cdfda6 139 Pfam PF03479 Domain of unknown function (DUF296) 8 118 1.3E-19 T 23-10-2018 IPR005175 PPC domain TON_0925 d4d5267981664ee37ce5a100f8cdfda6 139 Gene3D G3DSA:3.30.1330.80 1 139 1.2E-47 T 23-10-2018 TON_0925 d4d5267981664ee37ce5a100f8cdfda6 139 PIRSF PIRSF016702 1 139 1.3E-42 T 23-10-2018 IPR025707 Predicted DNA-binding protein with PD1-like DNA-binding motif TON_0925 d4d5267981664ee37ce5a100f8cdfda6 139 SUPERFAMILY SSF117856 4 129 1.05E-35 T 23-10-2018 TON_0219 9a8e2e902f7b7b8f8f424044da5c08f8 391 Pfam PF04998 RNA polymerase Rpb1, domain 5 49 332 3.5E-57 T 23-10-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TON_0219 9a8e2e902f7b7b8f8f424044da5c08f8 391 TIGRFAM TIGR02389 RNA_pol_rpoA2: DNA-directed RNA polymerase, subunit A'' 16 382 2.4E-152 T 23-10-2018 IPR012757 DNA-directed RNA polymerase subunit A'' GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TON_0219 9a8e2e902f7b7b8f8f424044da5c08f8 391 Gene3D G3DSA:1.10.150.390 333 378 6.4E-23 T 23-10-2018 TON_0219 9a8e2e902f7b7b8f8f424044da5c08f8 391 Hamap MF_00411 DNA-directed RNA polymerase subunit A'' [rpoA2]. 3 385 41.396 T 23-10-2018 IPR012757 DNA-directed RNA polymerase subunit A'' GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TON_0219 9a8e2e902f7b7b8f8f424044da5c08f8 391 SUPERFAMILY SSF64484 27 385 9.84E-107 T 23-10-2018 TON_0663 a60dcf3fc2ea2f5324dc802510990f0a 173 Pfam PF01928 CYTH domain 2 160 4.3E-24 T 23-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 TON_0663 a60dcf3fc2ea2f5324dc802510990f0a 173 ProDom PD009560 CYCLASE ADENYLATE CYCLASE ADENYLYL CYAB LYASE CLASS CYAB-TYPE THERMOPHILIC MJ0240 2 141 2.0E-54 T 23-10-2018 TON_0663 a60dcf3fc2ea2f5324dc802510990f0a 173 Gene3D G3DSA:2.40.320.10 1 171 2.3E-48 T 23-10-2018 TON_0663 a60dcf3fc2ea2f5324dc802510990f0a 173 TIGRFAM TIGR00318 cyaB: putative adenylyl cyclase CyaB 1 164 1.4E-32 T 23-10-2018 IPR008173 Adenylyl cyclase CyaB KEGG: 00230+4.6.1.1 TON_0663 a60dcf3fc2ea2f5324dc802510990f0a 173 SUPERFAMILY SSF55154 1 164 3.27E-39 T 23-10-2018 IPR033469 CYTH-like domain superfamily Reactome: R-HSA-196819 TON_0663 a60dcf3fc2ea2f5324dc802510990f0a 173 SMART SM01118 1 166 3.2E-12 T 23-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 TON_0362 cb2a8cb60a8ebdadbc545d2f46e43b26 295 Gene3D G3DSA:3.90.230.10 9 286 7.7E-108 T 23-10-2018 TON_0362 cb2a8cb60a8ebdadbc545d2f46e43b26 295 ProSitePatterns PS01202 Methionine aminopeptidase subfamily 2 signature. 78 94 - T 23-10-2018 IPR018349 Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site MetaCyc: PWY-7799|MetaCyc: PWY-7800 TON_0362 cb2a8cb60a8ebdadbc545d2f46e43b26 295 Pfam PF00557 Metallopeptidase family M24 7 287 2.7E-44 T 23-10-2018 IPR000994 Peptidase M24 TON_0362 cb2a8cb60a8ebdadbc545d2f46e43b26 295 SUPERFAMILY SSF46785 196 271 2.45E-16 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TON_0362 cb2a8cb60a8ebdadbc545d2f46e43b26 295 Gene3D G3DSA:1.10.10.10 196 272 7.7E-108 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TON_0362 cb2a8cb60a8ebdadbc545d2f46e43b26 295 Hamap MF_01975 Methionine aminopeptidase [map]. 4 295 48.071 T 23-10-2018 IPR028595 Methionine aminopeptidase, archaeal GO:0004177|GO:0006508 MetaCyc: PWY-7799|MetaCyc: PWY-7800 TON_0362 cb2a8cb60a8ebdadbc545d2f46e43b26 295 PRINTS PR00599 Methionine aminopeptidase-1 signature 145 157 2.0E-16 T 23-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 TON_0362 cb2a8cb60a8ebdadbc545d2f46e43b26 295 PRINTS PR00599 Methionine aminopeptidase-1 signature 78 94 2.0E-16 T 23-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 TON_0362 cb2a8cb60a8ebdadbc545d2f46e43b26 295 PRINTS PR00599 Methionine aminopeptidase-1 signature 53 66 2.0E-16 T 23-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 TON_0362 cb2a8cb60a8ebdadbc545d2f46e43b26 295 PRINTS PR00599 Methionine aminopeptidase-1 signature 177 189 2.0E-16 T 23-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 TON_0362 cb2a8cb60a8ebdadbc545d2f46e43b26 295 TIGRFAM TIGR00501 met_pdase_II: methionine aminopeptidase, type II 2 295 9.0E-119 T 23-10-2018 IPR002468 Peptidase M24A, methionine aminopeptidase, subfamily 2 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800|Reactome: R-HSA-2514859 TON_0362 cb2a8cb60a8ebdadbc545d2f46e43b26 295 SUPERFAMILY SSF55920 3 295 4.06E-68 T 23-10-2018 IPR036005 Creatinase/aminopeptidase-like TON_0969 7683ac5fbfaca84c9140a2c0e5735fe5 631 Pfam PF00326 Prolyl oligopeptidase family 420 630 7.3E-60 T 23-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 TON_0969 7683ac5fbfaca84c9140a2c0e5735fe5 631 Gene3D G3DSA:2.120.10.30 20 148 1.9E-16 T 23-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like TON_0969 7683ac5fbfaca84c9140a2c0e5735fe5 631 SUPERFAMILY SSF53474 373 630 4.57E-72 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold TON_0969 7683ac5fbfaca84c9140a2c0e5735fe5 631 Pfam PF07676 WD40-like Beta Propeller Repeat 53 89 3.0E-8 T 23-10-2018 IPR011659 WD40-like Beta Propeller TON_0969 7683ac5fbfaca84c9140a2c0e5735fe5 631 Gene3D G3DSA:2.120.10.30 149 286 1.0E-6 T 23-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like TON_0969 7683ac5fbfaca84c9140a2c0e5735fe5 631 Gene3D G3DSA:3.40.50.1820 376 631 1.1E-73 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold TON_0969 7683ac5fbfaca84c9140a2c0e5735fe5 631 SUPERFAMILY SSF82171 22 366 3.01E-33 T 23-10-2018 TON_0221 d7067cb0e5e35e84e15ab642d85d9e60 145 Hamap MF_00945_A Transcription termination/antitermination protein NusA [nusA]. 1 145 30.191 T 23-10-2018 IPR010212 Probable transcription termination protein NusA, archaeal TON_0221 d7067cb0e5e35e84e15ab642d85d9e60 145 Pfam PF07650 KH domain 12 94 1.1E-17 T 23-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0221 d7067cb0e5e35e84e15ab642d85d9e60 145 Gene3D G3DSA:3.30.300.20 2 73 1.5E-27 T 23-10-2018 IPR015946 K homology domain-like, alpha/beta TON_0221 d7067cb0e5e35e84e15ab642d85d9e60 145 SUPERFAMILY SSF54814 12 74 6.54E-12 T 23-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 TON_0221 d7067cb0e5e35e84e15ab642d85d9e60 145 SMART SM00322 32 115 0.0021 T 23-10-2018 IPR004087 K Homology domain GO:0003676 TON_0221 d7067cb0e5e35e84e15ab642d85d9e60 145 Gene3D G3DSA:3.30.300.20 74 144 5.9E-22 T 23-10-2018 IPR015946 K homology domain-like, alpha/beta TON_0221 d7067cb0e5e35e84e15ab642d85d9e60 145 TIGRFAM TIGR01952 nusA_arch: NusA family KH domain protein, archaeal 1 145 2.4E-60 T 23-10-2018 IPR010212 Probable transcription termination protein NusA, archaeal TON_0221 d7067cb0e5e35e84e15ab642d85d9e60 145 SUPERFAMILY SSF54814 88 141 6.54E-7 T 23-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 TON_1372 a0f2e81be486a02bf6fb7484ce154f0b 264 Gene3D G3DSA:3.30.950.10 115 264 2.0E-53 T 23-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 TON_1372 a0f2e81be486a02bf6fb7484ce154f0b 264 Gene3D G3DSA:3.40.1010.10 1 114 2.3E-41 T 23-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 TON_1372 a0f2e81be486a02bf6fb7484ce154f0b 264 TIGRFAM TIGR00522 dph5: diphthine synthase 3 256 2.8E-102 T 23-10-2018 IPR004551 Diphthine synthase GO:0004164|GO:0017183 Reactome: R-HSA-5358493 TON_1372 a0f2e81be486a02bf6fb7484ce154f0b 264 Hamap MF_01084 Diphthine synthase [dphB]. 2 256 36.2 T 23-10-2018 IPR004551 Diphthine synthase GO:0004164|GO:0017183 Reactome: R-HSA-5358493 TON_1372 a0f2e81be486a02bf6fb7484ce154f0b 264 SUPERFAMILY SSF53790 1 259 6.28E-64 T 23-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 TON_1372 a0f2e81be486a02bf6fb7484ce154f0b 264 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 3 213 7.0E-23 T 23-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 TON_1372 a0f2e81be486a02bf6fb7484ce154f0b 264 PIRSF PIRSF036432 2 260 4.6E-98 T 23-10-2018 IPR004551 Diphthine synthase GO:0004164|GO:0017183 Reactome: R-HSA-5358493 TON_0798 73efb479d6949241b78b1766b14fdc25 404 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 193 374 1.0E-55 T 23-10-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 TON_0798 73efb479d6949241b78b1766b14fdc25 404 SUPERFAMILY SSF52507 18 217 2.35E-47 T 23-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 TON_0798 73efb479d6949241b78b1766b14fdc25 404 Pfam PF02441 Flavoprotein 19 188 2.5E-41 T 23-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 TON_0798 73efb479d6949241b78b1766b14fdc25 404 SUPERFAMILY SSF102645 180 402 6.41E-66 T 23-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 TON_0798 73efb479d6949241b78b1766b14fdc25 404 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 18 399 9.3E-127 T 23-10-2018 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5|MetaCyc: PWY-7851 TON_0798 73efb479d6949241b78b1766b14fdc25 404 Gene3D G3DSA:3.40.50.10300 189 403 3.9E-69 T 23-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 TON_0798 73efb479d6949241b78b1766b14fdc25 404 Gene3D G3DSA:3.40.50.1950 15 188 3.2E-48 T 23-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 TON_1481 e05759dfab26c532e55c71043156286e 394 Gene3D G3DSA:3.40.50.920 253 391 4.3E-40 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TON_1481 e05759dfab26c532e55c71043156286e 394 Gene3D G3DSA:3.40.50.970 2 252 5.0E-103 T 23-10-2018 TON_1481 e05759dfab26c532e55c71043156286e 394 SUPERFAMILY SSF52922 254 369 2.62E-32 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TON_1481 e05759dfab26c532e55c71043156286e 394 SUPERFAMILY SSF52518 4 251 9.16E-69 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold TON_1481 e05759dfab26c532e55c71043156286e 394 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 16 240 3.5E-79 T 23-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 TON_1481 e05759dfab26c532e55c71043156286e 394 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 262 365 1.2E-29 T 23-10-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II TON_1241 2e324c1e12ccf7d3510a38c08aca7afe 117 Gene3D G3DSA:3.40.1230.10 1 117 7.2E-34 T 23-10-2018 IPR036748 MTH938-like superfamily TON_1241 2e324c1e12ccf7d3510a38c08aca7afe 117 SUPERFAMILY SSF64076 2 117 7.85E-33 T 23-10-2018 IPR036748 MTH938-like superfamily TON_1241 2e324c1e12ccf7d3510a38c08aca7afe 117 Pfam PF04430 Protein of unknown function (DUF498/DUF598) 6 112 3.4E-11 T 23-10-2018 IPR007523 NDUFAF3/Mth938 domain-containing protein TON_1729 4ddeb353dcd98ec2586645f642486747 909 SUPERFAMILY SSF55186 599 748 8.37E-48 T 23-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 TON_1729 4ddeb353dcd98ec2586645f642486747 909 Gene3D G3DSA:3.10.310.40 809 909 1.2E-19 T 23-10-2018 TON_1729 4ddeb353dcd98ec2586645f642486747 909 PRINTS PR00980 Alanyl-tRNA synthetase signature 245 258 4.5E-22 T 23-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 TON_1729 4ddeb353dcd98ec2586645f642486747 909 PRINTS PR00980 Alanyl-tRNA synthetase signature 336 352 4.5E-22 T 23-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 TON_1729 4ddeb353dcd98ec2586645f642486747 909 PRINTS PR00980 Alanyl-tRNA synthetase signature 206 217 4.5E-22 T 23-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 TON_1729 4ddeb353dcd98ec2586645f642486747 909 PRINTS PR00980 Alanyl-tRNA synthetase signature 360 373 4.5E-22 T 23-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 TON_1729 4ddeb353dcd98ec2586645f642486747 909 PRINTS PR00980 Alanyl-tRNA synthetase signature 127 138 4.5E-22 T 23-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 TON_1729 4ddeb353dcd98ec2586645f642486747 909 Gene3D G3DSA:3.30.930.10 1 260 3.1E-114 T 23-10-2018 TON_1729 4ddeb353dcd98ec2586645f642486747 909 Gene3D G3DSA:3.30.54.20 671 722 6.4E-29 T 23-10-2018 TON_1729 4ddeb353dcd98ec2586645f642486747 909 Hamap MF_00036_A Alanine--tRNA ligase [alaS]. 4 906 24.055 T 23-10-2018 IPR022429 Alanine-tRNA ligase, archaea GO:0000166|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 TON_1729 4ddeb353dcd98ec2586645f642486747 909 TIGRFAM TIGR03683 A-tRNA_syn_arch: alanine--tRNA ligase 4 907 0.0 T 23-10-2018 IPR022429 Alanine-tRNA ligase, archaea GO:0000166|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 TON_1729 4ddeb353dcd98ec2586645f642486747 909 Pfam PF01411 tRNA synthetases class II (A) 61 599 4.6E-159 T 23-10-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 TON_1729 4ddeb353dcd98ec2586645f642486747 909 SUPERFAMILY SSF55681 57 264 3.48E-58 T 23-10-2018 TON_1729 4ddeb353dcd98ec2586645f642486747 909 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 698 740 2.9E-15 T 23-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 TON_1729 4ddeb353dcd98ec2586645f642486747 909 Gene3D G3DSA:3.30.980.10 601 670 2.9E-21 T 23-10-2018 TON_1729 4ddeb353dcd98ec2586645f642486747 909 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 61 889 8.8E-230 T 23-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 TON_1729 4ddeb353dcd98ec2586645f642486747 909 SUPERFAMILY SSF50447 512 595 5.65E-20 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily TON_1729 4ddeb353dcd98ec2586645f642486747 909 SUPERFAMILY SSF101353 308 501 6.02E-50 T 23-10-2018 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain superfamily GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 TON_1729 4ddeb353dcd98ec2586645f642486747 909 Gene3D G3DSA:2.40.30.130 502 595 9.6E-35 T 23-10-2018 TON_1729 4ddeb353dcd98ec2586645f642486747 909 Pfam PF02272 DHHA1 domain 780 907 6.1E-19 T 23-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 TON_1729 4ddeb353dcd98ec2586645f642486747 909 SMART SM00863 698 741 1.1E-17 T 23-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 TON_0065 7e3f99856f7fa09825305b55a5eed766 305 Gene3D G3DSA:2.40.50.140 140 202 6.0E-75 T 23-10-2018 TON_0065 7e3f99856f7fa09825305b55a5eed766 305 SUPERFAMILY SSF50249 140 205 5.31E-11 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold TON_0065 7e3f99856f7fa09825305b55a5eed766 305 SUPERFAMILY SSF75217 53 303 1.05E-45 T 23-10-2018 IPR029028 Alpha/beta knot methyltransferases TON_0065 7e3f99856f7fa09825305b55a5eed766 305 Pfam PF02598 Putative RNA methyltransferase 53 298 2.0E-49 T 23-10-2018 IPR003750 Putative RNA methyltransferase TON_0065 7e3f99856f7fa09825305b55a5eed766 305 Gene3D G3DSA:3.40.1280.10 54 301 6.0E-75 T 23-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal TON_1366 39d673404bab4920decb7ce063476c6f 440 SUPERFAMILY SSF56784 1 217 9.32E-35 T 23-10-2018 IPR036412 HAD-like superfamily TON_1366 39d673404bab4920decb7ce063476c6f 440 Gene3D G3DSA:3.40.50.1000 5 208 1.5E-27 T 23-10-2018 IPR023214 HAD superfamily TON_1366 39d673404bab4920decb7ce063476c6f 440 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 84 177 9.3E-6 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TON_1366 39d673404bab4920decb7ce063476c6f 440 Gene3D G3DSA:1.10.150.520 17 82 1.5E-27 T 23-10-2018 TON_1366 39d673404bab4920decb7ce063476c6f 440 SUPERFAMILY SSF53448 218 430 2.14E-32 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TON_1366 39d673404bab4920decb7ce063476c6f 440 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 172 185 4.3E-9 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TON_1366 39d673404bab4920decb7ce063476c6f 440 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 94 107 4.3E-9 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TON_1366 39d673404bab4920decb7ce063476c6f 440 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 3 14 4.3E-9 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TON_1366 39d673404bab4920decb7ce063476c6f 440 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 145 165 4.3E-9 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TON_1366 39d673404bab4920decb7ce063476c6f 440 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 182 2.1E-21 T 23-10-2018 TON_1366 39d673404bab4920decb7ce063476c6f 440 Gene3D G3DSA:3.90.550.10 214 436 4.3E-47 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TON_1366 39d673404bab4920decb7ce063476c6f 440 Pfam PF00535 Glycosyl transferase family 2 221 343 3.7E-23 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TON_0993 6aa87faef962f85d9aff58107af29832 328 Pfam PF00005 ABC transporter 20 162 6.9E-35 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TON_0993 6aa87faef962f85d9aff58107af29832 328 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TON_0993 6aa87faef962f85d9aff58107af29832 328 SUPERFAMILY SSF52540 3 224 5.33E-71 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_0993 6aa87faef962f85d9aff58107af29832 328 Gene3D G3DSA:3.40.50.300 1 232 4.6E-76 T 23-10-2018 TON_0993 6aa87faef962f85d9aff58107af29832 328 Pfam PF13732 Domain of unknown function (DUF4162) 217 303 4.4E-9 T 23-10-2018 IPR025302 Domain of unknown function DUF4162 TON_0993 6aa87faef962f85d9aff58107af29832 328 SMART SM00382 28 212 1.5E-9 T 23-10-2018 IPR003593 AAA+ ATPase domain TON_0993 6aa87faef962f85d9aff58107af29832 328 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 11 305 2.2E-122 T 23-10-2018 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 TON_0004 7a0a5d8a9893e3cd220915c0e4d6d238 213 Pfam PF09622 Putative integral membrane protein (DUF2391) 86 206 3.9E-11 T 23-10-2018 IPR024464 Protein of unknown function DUF2391 TON_0160 b5d508caf81e02dd795a958735dc712a 257 Gene3D G3DSA:3.40.50.300 1 235 5.7E-60 T 23-10-2018 TON_0160 b5d508caf81e02dd795a958735dc712a 257 SMART SM00382 26 246 7.1E-9 T 23-10-2018 IPR003593 AAA+ ATPase domain TON_0160 b5d508caf81e02dd795a958735dc712a 257 SUPERFAMILY SSF52540 2 228 1.11E-55 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_0160 b5d508caf81e02dd795a958735dc712a 257 Pfam PF00005 ABC transporter 19 162 2.0E-31 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TON_0451 dfeb26941a409252937dd4e3adf482df 116 TIGRFAM TIGR02338 gimC_beta: prefoldin, beta subunit 4 112 1.6E-39 T 23-10-2018 IPR012713 Prefoldin subunit beta GO:0006457|GO:0016272|GO:0051082 TON_0451 dfeb26941a409252937dd4e3adf482df 116 Hamap MF_00307 Prefoldin subunit beta [pfdB]. 1 116 49.769 T 23-10-2018 IPR012713 Prefoldin subunit beta GO:0006457|GO:0016272|GO:0051082 TON_0451 dfeb26941a409252937dd4e3adf482df 116 Gene3D G3DSA:1.10.287.370 1 116 6.5E-39 T 23-10-2018 IPR009053 Prefoldin TON_0451 dfeb26941a409252937dd4e3adf482df 116 Pfam PF01920 Prefoldin subunit 9 111 1.4E-23 T 23-10-2018 IPR002777 Prefoldin beta-like GO:0006457|GO:0016272|GO:0051082 Reactome: R-HSA-389957 TON_0451 dfeb26941a409252937dd4e3adf482df 116 SUPERFAMILY SSF46579 6 111 2.49E-22 T 23-10-2018 TON_0279 c07cd2b56959ba085f1360f45eec47ee 483 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 71 121 1.1E-5 T 23-10-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_0279 c07cd2b56959ba085f1360f45eec47ee 483 Pfam PF00361 Proton-conducting membrane transporter 137 416 9.4E-52 T 23-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_0279 c07cd2b56959ba085f1360f45eec47ee 483 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 111 131 1.7E-26 T 23-10-2018 TON_0279 c07cd2b56959ba085f1360f45eec47ee 483 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 76 101 1.7E-26 T 23-10-2018 TON_0279 c07cd2b56959ba085f1360f45eec47ee 483 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 219 240 1.7E-26 T 23-10-2018 TON_0279 c07cd2b56959ba085f1360f45eec47ee 483 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 241 267 1.7E-26 T 23-10-2018 TON_0279 c07cd2b56959ba085f1360f45eec47ee 483 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 157 178 1.7E-26 T 23-10-2018 TON_0612 7a6832d783b117fd1bb418ffb7aa3f78 234 PRINTS PR01874 DNA repair protein radA signature 15 43 4.1E-9 T 23-10-2018 TON_0612 7a6832d783b117fd1bb418ffb7aa3f78 234 PRINTS PR01874 DNA repair protein radA signature 57 74 4.1E-9 T 23-10-2018 TON_0612 7a6832d783b117fd1bb418ffb7aa3f78 234 Pfam PF06745 KaiC 6 228 1.5E-51 T 23-10-2018 IPR014774 KaiC-like domain TON_0612 7a6832d783b117fd1bb418ffb7aa3f78 234 SUPERFAMILY SSF52540 4 227 1.76E-40 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_0612 7a6832d783b117fd1bb418ffb7aa3f78 234 Gene3D G3DSA:3.40.50.300 1 231 1.7E-57 T 23-10-2018 TON_0612 7a6832d783b117fd1bb418ffb7aa3f78 234 SMART SM00382 23 190 3.9E-4 T 23-10-2018 IPR003593 AAA+ ATPase domain TON_1175 b1e3fddf7726e04fdbefa8061dc932b4 207 Pfam PF12710 haloacid dehalogenase-like hydrolase 5 171 4.3E-20 T 23-10-2018 TON_1175 b1e3fddf7726e04fdbefa8061dc932b4 207 SUPERFAMILY SSF56784 2 205 2.0E-42 T 23-10-2018 IPR036412 HAD-like superfamily TON_1175 b1e3fddf7726e04fdbefa8061dc932b4 207 TIGRFAM TIGR01491 HAD-SF-IB-PSPlk: phosphoserine phosphatase-like hydrolase, archaeal 1 183 3.6E-56 T 23-10-2018 IPR006386 HAD-superfamily hydrolase, subfamily IB, PSPase-like, archaeal TON_1175 b1e3fddf7726e04fdbefa8061dc932b4 207 Gene3D G3DSA:3.40.50.1000 1 203 2.7E-51 T 23-10-2018 IPR023214 HAD superfamily TON_1175 b1e3fddf7726e04fdbefa8061dc932b4 207 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 4 173 1.3E-32 T 23-10-2018 TON_0960 90c0013f85120cdaa768293d8d1f0109 420 SUPERFAMILY SSF51338 12 404 2.59E-23 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 TON_0960 90c0013f85120cdaa768293d8d1f0109 420 Pfam PF01979 Amidohydrolase family 51 395 7.6E-58 T 23-10-2018 IPR006680 Amidohydrolase-related GO:0016787 TON_0960 90c0013f85120cdaa768293d8d1f0109 420 SUPERFAMILY SSF51556 54 344 1.58E-80 T 23-10-2018 IPR032466 Metal-dependent hydrolase TON_0960 90c0013f85120cdaa768293d8d1f0109 420 Gene3D G3DSA:3.20.20.140 55 341 5.6E-120 T 23-10-2018 TON_0960 90c0013f85120cdaa768293d8d1f0109 420 Gene3D G3DSA:2.30.40.10 7 404 5.6E-120 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 TON_1025 1ca350a1a183e86e0518b094d5bf7abe 94 Pfam PF04066 Multiple resistance and pH regulation protein F (MrpF / PhaF) 36 87 3.1E-11 T 23-10-2018 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 TON_1269 824126d5de0addbee5dcfd8ee89aabd3 636 SUPERFAMILY SSF102114 335 555 1.7E-13 T 23-10-2018 TON_1269 824126d5de0addbee5dcfd8ee89aabd3 636 Gene3D G3DSA:3.20.20.70 269 568 4.3E-74 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TON_1269 824126d5de0addbee5dcfd8ee89aabd3 636 TIGRFAM TIGR00238 TIGR00238: KamA family protein 211 567 1.8E-112 T 23-10-2018 IPR003739 Lysine-2,3-aminomutase/glutamate 2,3-aminomutase TON_0220 0ea2b6c0d7e406a8519423fb48b5b391 100 SUPERFAMILY SSF55315 1 95 2.52E-27 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like TON_0220 0ea2b6c0d7e406a8519423fb48b5b391 100 Pfam PF01248 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family 5 94 1.2E-19 T 23-10-2018 IPR004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45 TON_0220 0ea2b6c0d7e406a8519423fb48b5b391 100 ProSitePatterns PS00709 Ribosomal protein L30e signature 1. 13 37 - T 23-10-2018 IPR022991 Ribosomal protein L30e, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0220 0ea2b6c0d7e406a8519423fb48b5b391 100 Hamap MF_00481 50S ribosomal protein L30e [rpl30e]. 1 98 29.244 T 23-10-2018 IPR000231 Ribosomal protein L30e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0220 0ea2b6c0d7e406a8519423fb48b5b391 100 ProSitePatterns PS00993 Ribosomal protein L30e signature 2. 69 89 - T 23-10-2018 IPR022991 Ribosomal protein L30e, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0220 0ea2b6c0d7e406a8519423fb48b5b391 100 Gene3D G3DSA:3.30.1330.30 1 100 8.3E-38 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like TON_0868 2051beb268f8f6b83e5e36115f5af896 115 TIGRFAM TIGR00332 neela_ferrous: desulfoferrodoxin ferrous iron-binding domain 8 114 7.4E-34 T 23-10-2018 IPR002742 Desulfoferrodoxin, ferrous iron-binding domain GO:0005506|GO:0016491|GO:0055114 TON_0868 2051beb268f8f6b83e5e36115f5af896 115 SUPERFAMILY SSF49367 6 114 6.93E-40 T 23-10-2018 IPR036073 Desulfoferrodoxin, ferrous iron-binding domain superfamily GO:0005506|GO:0016491|GO:0055114 TON_0868 2051beb268f8f6b83e5e36115f5af896 115 Gene3D G3DSA:2.60.40.730 1 115 1.3E-51 T 23-10-2018 IPR036073 Desulfoferrodoxin, ferrous iron-binding domain superfamily GO:0005506|GO:0016491|GO:0055114 TON_0868 2051beb268f8f6b83e5e36115f5af896 115 Pfam PF01880 Desulfoferrodoxin 9 111 1.6E-32 T 23-10-2018 IPR002742 Desulfoferrodoxin, ferrous iron-binding domain GO:0005506|GO:0016491|GO:0055114 TON_0413 00131bfde17de62138466f562e8a5dea 618 TIGRFAM TIGR01564 S_layer_MJ: S-layer protein 4 615 5.8E-59 T 23-10-2018 IPR006454 S-layer protein GO:0005618 TON_0413 00131bfde17de62138466f562e8a5dea 618 Pfam PF05123 S-layer like family, N-terminal region 4 305 6.7E-44 T 23-10-2018 IPR022650 S-layer protein, N-terminal TON_0413 00131bfde17de62138466f562e8a5dea 618 Pfam PF05124 S-layer like family, C-terminal region 420 615 3.2E-30 T 23-10-2018 IPR022651 S-layer protein, C-terminal TON_1551 1fed44d0ad92fb63d43f4fc90183b2ec 224 Gene3D G3DSA:1.20.58.220 1 224 1.7E-50 T 23-10-2018 IPR038078 PhoU-like domain superfamily TON_1551 1fed44d0ad92fb63d43f4fc90183b2ec 224 Pfam PF01865 Protein of unknown function DUF47 6 222 2.5E-43 T 23-10-2018 IPR018445 Putative phosphate transport regulator TON_1551 1fed44d0ad92fb63d43f4fc90183b2ec 224 TIGRFAM TIGR00153 TIGR00153: TIGR00153 family protein 5 222 2.1E-35 T 23-10-2018 IPR002727 Protein of unknown function DUF47 TON_1551 1fed44d0ad92fb63d43f4fc90183b2ec 224 SUPERFAMILY SSF109755 26 221 1.44E-16 T 23-10-2018 TON_1265 eb9bca6ea304b11c16bcb9c9f2e88bd3 478 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 60 68 - T 23-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 TON_1265 eb9bca6ea304b11c16bcb9c9f2e88bd3 478 Gene3D G3DSA:3.50.50.60 237 367 1.4E-58 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TON_1265 eb9bca6ea304b11c16bcb9c9f2e88bd3 478 Gene3D G3DSA:3.50.50.60 118 441 1.4E-58 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TON_1265 eb9bca6ea304b11c16bcb9c9f2e88bd3 478 SUPERFAMILY SSF51905 114 433 8.67E-41 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TON_1265 eb9bca6ea304b11c16bcb9c9f2e88bd3 478 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 360 374 4.7E-22 T 23-10-2018 TON_1265 eb9bca6ea304b11c16bcb9c9f2e88bd3 478 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 406 413 4.7E-22 T 23-10-2018 TON_1265 eb9bca6ea304b11c16bcb9c9f2e88bd3 478 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 228 237 4.7E-22 T 23-10-2018 TON_1265 eb9bca6ea304b11c16bcb9c9f2e88bd3 478 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 118 140 4.7E-22 T 23-10-2018 TON_1265 eb9bca6ea304b11c16bcb9c9f2e88bd3 478 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 269 294 4.7E-22 T 23-10-2018 TON_1265 eb9bca6ea304b11c16bcb9c9f2e88bd3 478 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 118 425 3.2E-39 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TON_1265 eb9bca6ea304b11c16bcb9c9f2e88bd3 478 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 15 95 2.7E-26 T 23-10-2018 TON_1265 eb9bca6ea304b11c16bcb9c9f2e88bd3 478 Gene3D G3DSA:3.10.20.440 4 101 2.3E-32 T 23-10-2018 TON_1265 eb9bca6ea304b11c16bcb9c9f2e88bd3 478 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 225 243 1.4E-26 T 23-10-2018 TON_1265 eb9bca6ea304b11c16bcb9c9f2e88bd3 478 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 391 413 1.4E-26 T 23-10-2018 TON_1265 eb9bca6ea304b11c16bcb9c9f2e88bd3 478 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 119 138 1.4E-26 T 23-10-2018 TON_1265 eb9bca6ea304b11c16bcb9c9f2e88bd3 478 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 269 287 1.4E-26 T 23-10-2018 TON_1265 eb9bca6ea304b11c16bcb9c9f2e88bd3 478 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 359 375 1.4E-26 T 23-10-2018 TON_1265 eb9bca6ea304b11c16bcb9c9f2e88bd3 478 SUPERFAMILY SSF54292 18 98 1.48E-20 T 23-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 TON_0620 00be5074b8500a73f973252441afcfad 242 Pfam PF02195 ParB-like nuclease domain 22 92 1.5E-9 T 23-10-2018 IPR003115 ParB/Sulfiredoxin TON_0620 00be5074b8500a73f973252441afcfad 242 SMART SM00470 19 114 1.2E-13 T 23-10-2018 IPR003115 ParB/Sulfiredoxin TON_0620 00be5074b8500a73f973252441afcfad 242 Gene3D G3DSA:3.30.1760.10 98 227 7.2E-83 T 23-10-2018 IPR023098 ParB-like nuclease, C-terminal TON_0620 00be5074b8500a73f973252441afcfad 242 SUPERFAMILY SSF110849 14 241 6.28E-62 T 23-10-2018 IPR036086 ParB/Sulfiredoxin superfamily TON_0620 00be5074b8500a73f973252441afcfad 242 Gene3D G3DSA:3.90.1530.10 17 238 7.2E-83 T 23-10-2018 TON_0996 bb4fcf33dd32912817e1f46aa02a8efb 243 Gene3D G3DSA:1.10.340.30 40 153 2.5E-63 T 23-10-2018 TON_0996 bb4fcf33dd32912817e1f46aa02a8efb 243 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 53 190 3.1E-17 T 23-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 TON_0996 bb4fcf33dd32912817e1f46aa02a8efb 243 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 209 225 - T 23-10-2018 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 TON_0996 bb4fcf33dd32912817e1f46aa02a8efb 243 SUPERFAMILY SSF48150 25 228 4.55E-62 T 23-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 TON_0996 bb4fcf33dd32912817e1f46aa02a8efb 243 PIRSF PIRSF001435 19 232 8.6E-42 T 23-10-2018 TON_0996 bb4fcf33dd32912817e1f46aa02a8efb 243 ProSitePatterns PS01155 Endonuclease III family signature. 123 152 - T 23-10-2018 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 TON_0996 bb4fcf33dd32912817e1f46aa02a8efb 243 Gene3D G3DSA:1.10.1670.10 37 225 2.5E-63 T 23-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 TON_0996 bb4fcf33dd32912817e1f46aa02a8efb 243 Pfam PF00633 Helix-hairpin-helix motif 120 149 1.6E-6 T 23-10-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 TON_0996 bb4fcf33dd32912817e1f46aa02a8efb 243 SMART SM00525 208 228 8.0E-7 T 23-10-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 TON_0996 bb4fcf33dd32912817e1f46aa02a8efb 243 SMART SM00478 57 207 4.0E-57 T 23-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 TON_0996 bb4fcf33dd32912817e1f46aa02a8efb 243 Hamap MF_00942 Endonuclease III [nth]. 21 231 33.04 T 23-10-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 TON_0058 04a5152a2acbf497834dc18ee3d0afa0 300 SUPERFAMILY SSF55681 7 296 3.59E-55 T 23-10-2018 TON_0058 04a5152a2acbf497834dc18ee3d0afa0 300 Gene3D G3DSA:3.30.930.10 1 299 7.8E-74 T 23-10-2018 TON_0058 04a5152a2acbf497834dc18ee3d0afa0 300 Pfam PF00152 tRNA synthetases class II (D, K and N) 3 292 6.0E-43 T 23-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 TON_0454 e2c1ef118ef2dfe41fe2ade9dc48a818 49 SMART SM00659 4 49 1.9E-20 T 23-10-2018 IPR006591 RNA polymerase archaeal subunit P/eukaryotic subunit RPABC4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 TON_0454 e2c1ef118ef2dfe41fe2ade9dc48a818 49 Hamap MF_00615 DNA-directed RNA polymerase subunit P [rpoP]. 6 49 16.893 T 23-10-2018 IPR023464 DNA-directed RNA polymerase subunit P (Rpo12) GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TON_0454 e2c1ef118ef2dfe41fe2ade9dc48a818 49 Pfam PF03604 DNA directed RNA polymerase, 7 kDa subunit 6 39 2.4E-11 T 23-10-2018 IPR006591 RNA polymerase archaeal subunit P/eukaryotic subunit RPABC4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 TON_0454 e2c1ef118ef2dfe41fe2ade9dc48a818 49 SUPERFAMILY SSF63393 4 48 8.37E-13 T 23-10-2018 IPR029040 RNA polymerase subunit RPABC4/transcription elongation factor Spt4 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-75955 TON_0454 e2c1ef118ef2dfe41fe2ade9dc48a818 49 Gene3D G3DSA:2.20.28.30 1 49 7.7E-24 T 23-10-2018 TON_0648 d974ec0917ade2a9d40c0b49347dc68d 377 SUPERFAMILY SSF53335 4 374 2.3E-111 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TON_0648 d974ec0917ade2a9d40c0b49347dc68d 377 Gene3D G3DSA:3.40.50.150 1 316 8.7E-107 T 23-10-2018 TON_0648 d974ec0917ade2a9d40c0b49347dc68d 377 Pfam PF02005 N2,N2-dimethylguanosine tRNA methyltransferase 10 374 6.6E-115 T 23-10-2018 IPR002905 tRNA methyltransferase, Trm1 GO:0003723|GO:0004809|GO:0008033 MetaCyc: PWY-6829 TON_0648 d974ec0917ade2a9d40c0b49347dc68d 377 Gene3D G3DSA:3.30.56.70 317 376 1.9E-21 T 23-10-2018 TON_0648 d974ec0917ade2a9d40c0b49347dc68d 377 Hamap MF_00290 tRNA (guanine(26)-N(2))-dimethyltransferase [trm1]. 4 375 43.611 T 23-10-2018 IPR022923 tRNA (guanine(26)-N(2))-dimethyltransferase, archaeal and bacterial GO:0004809 MetaCyc: PWY-6829 TON_0648 d974ec0917ade2a9d40c0b49347dc68d 377 TIGRFAM TIGR00308 TRM1: N2,N2-dimethylguanosine tRNA methyltransferase 6 376 1.6E-99 T 23-10-2018 IPR002905 tRNA methyltransferase, Trm1 GO:0003723|GO:0004809|GO:0008033 MetaCyc: PWY-6829 TON_1486 a5e6e8e9a2580850a7e987f337b83207 178 Pfam PF02002 TFIIE alpha subunit 11 110 1.8E-24 T 23-10-2018 IPR024550 TFIIEalpha/SarR/Rpc3 HTH domain Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-674695|Reactome: R-HSA-6807505|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-76042 TON_1486 a5e6e8e9a2580850a7e987f337b83207 178 TIGRFAM TIGR00373 TIGR00373: transcription factor E 11 164 3.6E-48 T 23-10-2018 IPR016481 Transcription factor TFE, archaea GO:0006355 TON_1486 a5e6e8e9a2580850a7e987f337b83207 178 Hamap MF_01909 Transcription factor E [tfe]. 3 166 26.818 T 23-10-2018 IPR016481 Transcription factor TFE, archaea GO:0006355 TON_1486 a5e6e8e9a2580850a7e987f337b83207 178 Gene3D G3DSA:1.10.10.10 4 87 3.0E-27 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TON_1486 a5e6e8e9a2580850a7e987f337b83207 178 SMART SM00531 19 158 9.7E-56 T 23-10-2018 IPR002853 Transcription initiation factor IIE subunit alpha, N-terminal GO:0006367 Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-674695|Reactome: R-HSA-6807505|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-76042 TON_1486 a5e6e8e9a2580850a7e987f337b83207 178 PIRSF PIRSF006373 1 177 3.7E-70 T 23-10-2018 IPR016481 Transcription factor TFE, archaea GO:0006355 TON_1486 a5e6e8e9a2580850a7e987f337b83207 178 SUPERFAMILY SSF46785 6 87 2.2E-24 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TON_0919 1a2a8d72eb51b204de402f8e6995d429 197 SUPERFAMILY SSF53146 1 116 3.14E-29 T 23-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily TON_0919 1a2a8d72eb51b204de402f8e6995d429 197 Gene3D G3DSA:3.30.420.130 1 118 9.6E-29 T 23-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily TON_0919 1a2a8d72eb51b204de402f8e6995d429 197 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 13 107 1.0E-21 T 23-10-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis TON_1600 531e5d7e8c2efe33ebc03014297406de 401 SUPERFAMILY SSF52540 60 303 6.0E-23 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_1600 531e5d7e8c2efe33ebc03014297406de 401 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 66 204 1.2E-4 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TON_1600 531e5d7e8c2efe33ebc03014297406de 401 Gene3D G3DSA:3.40.50.300 45 235 4.0E-11 T 23-10-2018 TON_0453 815b1582b39f440ef7254fc175067594 213 SUPERFAMILY SSF52954 1 193 1.44E-34 T 23-10-2018 TON_0453 815b1582b39f440ef7254fc175067594 213 SMART SM00879 3 190 6.9E-16 T 23-10-2018 IPR007109 Brix domain TON_0453 815b1582b39f440ef7254fc175067594 213 Hamap MF_00699 Probable Brix domain-containing ribosomal biogenesis protein. 2 191 29.499 T 23-10-2018 IPR023548 Probable Brix domain-containing ribosomal biogenesis protein TON_0453 815b1582b39f440ef7254fc175067594 213 Gene3D G3DSA:3.40.50.10480 1 186 1.0E-32 T 23-10-2018 TON_0304 9c089d648b10f99a68b181b87d83fe6a 414 SUPERFAMILY SSF103473 37 411 6.8E-32 T 23-10-2018 IPR036259 MFS transporter superfamily TON_0304 9c089d648b10f99a68b181b87d83fe6a 414 Gene3D G3DSA:1.20.1250.20 28 413 1.3E-32 T 23-10-2018 TON_0304 9c089d648b10f99a68b181b87d83fe6a 414 Pfam PF07690 Major Facilitator Superfamily 43 381 1.0E-20 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TON_0637 4d23b6fa35b6d08e6b50e33ccd4f466d 275 Gene3D G3DSA:1.20.120.420 1 95 2.1E-31 T 23-10-2018 IPR027363 Methylthioribose-1-phosphate isomerase, N-terminal KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 TON_0637 4d23b6fa35b6d08e6b50e33ccd4f466d 275 SUPERFAMILY SSF100950 5 272 2.05E-68 T 23-10-2018 IPR037171 NagB/RpiA transferase-like TON_0637 4d23b6fa35b6d08e6b50e33ccd4f466d 275 Gene3D G3DSA:3.40.50.10470 96 275 4.3E-63 T 23-10-2018 TON_0637 4d23b6fa35b6d08e6b50e33ccd4f466d 275 Pfam PF01008 Initiation factor 2 subunit family 41 271 1.8E-52 T 23-10-2018 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 TON_0365 26f29a06c98db0941fcde95ec2409014 276 Gene3D G3DSA:1.25.40.10 4 218 2.0E-12 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TON_1785 cb7916eb3157419a778048830be3da74 422 SUPERFAMILY SSF53187 6 420 5.53E-64 T 23-10-2018 TON_1785 cb7916eb3157419a778048830be3da74 422 SUPERFAMILY SSF55031 212 323 1.7E-19 T 23-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain TON_1785 cb7916eb3157419a778048830be3da74 422 Gene3D G3DSA:3.40.630.10 25 410 1.5E-80 T 23-10-2018 TON_1785 cb7916eb3157419a778048830be3da74 422 Pfam PF07687 Peptidase dimerisation domain 207 318 1.6E-21 T 23-10-2018 IPR011650 Peptidase M20, dimerisation domain TON_1785 cb7916eb3157419a778048830be3da74 422 TIGRFAM TIGR01910 DapE-ArgE: peptidase, ArgE/DapE family 20 415 1.3E-80 T 23-10-2018 IPR010182 N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine deformylase/Succinyl-diaminopimelate desuccinylase TON_1785 cb7916eb3157419a778048830be3da74 422 Gene3D G3DSA:3.30.70.360 210 342 1.5E-80 T 23-10-2018 TON_1785 cb7916eb3157419a778048830be3da74 422 Pfam PF01546 Peptidase family M20/M25/M40 97 420 1.9E-37 T 23-10-2018 IPR002933 Peptidase M20 GO:0016787 TON_1222 827e023ccb78dcb65e7bfab42a0e9333 53 Pfam PF13380 CoA binding domain 2 46 2.6E-7 T 23-10-2018 IPR003781 CoA-binding GO:0048037 TON_1222 827e023ccb78dcb65e7bfab42a0e9333 53 SUPERFAMILY SSF51735 2 49 7.87E-7 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TON_1222 827e023ccb78dcb65e7bfab42a0e9333 53 Gene3D G3DSA:3.40.50.720 1 53 4.1E-9 T 23-10-2018 TON_0105 9dac6fa62b36d3ad4204bb85994fbbb7 260 SMART SM00662 14 254 9.5E-84 T 23-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TON_0105 9dac6fa62b36d3ad4204bb85994fbbb7 260 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 16 247 7.9E-19 T 23-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TON_0105 9dac6fa62b36d3ad4204bb85994fbbb7 260 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 46 148 9.2E-28 T 23-10-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TON_0105 9dac6fa62b36d3ad4204bb85994fbbb7 260 ProSitePatterns PS00446 RNA polymerases D / 30 to 40 Kd subunits signature. 28 68 - T 23-10-2018 IPR001514 DNA-directed RNA polymerase, 30-40kDa subunit, conserved site GO:0003677|GO:0003899|GO:0006351 TON_0105 9dac6fa62b36d3ad4204bb85994fbbb7 260 SUPERFAMILY SSF56553 39 149 6.41E-29 T 23-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TON_0105 9dac6fa62b36d3ad4204bb85994fbbb7 260 Hamap MF_00320 DNA-directed RNA polymerase subunit D [rpoD]. 3 257 32.735 T 23-10-2018 IPR022842 DNA-directed RNA polymerase subunit D (Rpo3) GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TON_0105 9dac6fa62b36d3ad4204bb85994fbbb7 260 Gene3D G3DSA:3.30.1360.10 7 251 3.1E-96 T 23-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TON_0105 9dac6fa62b36d3ad4204bb85994fbbb7 260 SUPERFAMILY SSF55257 3 257 4.91E-29 T 23-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TON_0105 9dac6fa62b36d3ad4204bb85994fbbb7 260 Gene3D G3DSA:3.30.70.3110 157 218 3.1E-96 T 23-10-2018 TON_0105 9dac6fa62b36d3ad4204bb85994fbbb7 260 Gene3D G3DSA:2.170.120.12 40 147 3.1E-96 T 23-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TON_0211 831f761fc1799a64936897923b3bccf7 229 Gene3D G3DSA:3.40.50.1000 3 136 5.4E-12 T 23-10-2018 IPR023214 HAD superfamily TON_0211 831f761fc1799a64936897923b3bccf7 229 Pfam PF13419 Haloacid dehalogenase-like hydrolase 3 135 7.3E-12 T 23-10-2018 TON_0211 831f761fc1799a64936897923b3bccf7 229 SUPERFAMILY SSF56784 1 184 8.95E-19 T 23-10-2018 IPR036412 HAD-like superfamily TON_0211 831f761fc1799a64936897923b3bccf7 229 Gene3D G3DSA:1.10.150.240 14 83 5.4E-12 T 23-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 TON_1212 48c7ff0e46ca59259bd2834b72846d0a 421 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 6 138 3.8E-36 T 23-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 TON_1212 48c7ff0e46ca59259bd2834b72846d0a 421 PIRSF PIRSF001109 1 421 1.8E-197 T 23-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 TON_1212 48c7ff0e46ca59259bd2834b72846d0a 421 SUPERFAMILY SSF52283 5 421 2.04E-103 T 23-10-2018 TON_1212 48c7ff0e46ca59259bd2834b72846d0a 421 Gene3D G3DSA:3.40.50.1480 9 410 6.2E-179 T 23-10-2018 TON_1212 48c7ff0e46ca59259bd2834b72846d0a 421 SMART SM00997 188 349 1.2E-110 T 23-10-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 TON_1212 48c7ff0e46ca59259bd2834b72846d0a 421 ProSitePatterns PS00738 S-adenosyl-L-homocysteine hydrolase signature 1. 78 92 - T 23-10-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 TON_1212 48c7ff0e46ca59259bd2834b72846d0a 421 Hamap MF_00563 Adenosylhomocysteinase [ahcY]. 2 421 50.727 T 23-10-2018 IPR034373 Adenosylhomocysteinase GO:0004013|GO:0019510|GO:0051287 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-2408508|Reactome: R-HSA-5578997 TON_1212 48c7ff0e46ca59259bd2834b72846d0a 421 SMART SM00996 6 420 2.2E-143 T 23-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 TON_1212 48c7ff0e46ca59259bd2834b72846d0a 421 Gene3D G3DSA:3.40.50.720 190 349 6.2E-179 T 23-10-2018 TON_1212 48c7ff0e46ca59259bd2834b72846d0a 421 ProSitePatterns PS00739 S-adenosyl-L-homocysteine hydrolase signature 2. 210 226 - T 23-10-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 TON_1212 48c7ff0e46ca59259bd2834b72846d0a 421 TIGRFAM TIGR00936 ahcY: adenosylhomocysteinase 7 421 5.7E-211 T 23-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 TON_1212 48c7ff0e46ca59259bd2834b72846d0a 421 SUPERFAMILY SSF51735 188 350 3.77E-68 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TON_1212 48c7ff0e46ca59259bd2834b72846d0a 421 Pfam PF00670 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 188 348 1.3E-50 T 23-10-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 TON_1212 48c7ff0e46ca59259bd2834b72846d0a 421 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 141 416 4.9E-29 T 23-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 TON_0817 5f0d8548a11cf9cff2c896ada0f9188d 242 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 93 193 2.5E-12 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TON_0817 5f0d8548a11cf9cff2c896ada0f9188d 242 Gene3D G3DSA:3.40.50.1000 4 219 1.4E-86 T 23-10-2018 IPR023214 HAD superfamily TON_0817 5f0d8548a11cf9cff2c896ada0f9188d 242 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 98 188 3.0E-12 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TON_0817 5f0d8548a11cf9cff2c896ada0f9188d 242 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 2 13 1.1E-9 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TON_0817 5f0d8548a11cf9cff2c896ada0f9188d 242 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 106 119 1.1E-9 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TON_0817 5f0d8548a11cf9cff2c896ada0f9188d 242 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 155 175 1.1E-9 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TON_0817 5f0d8548a11cf9cff2c896ada0f9188d 242 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 137 153 1.1E-9 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TON_0817 5f0d8548a11cf9cff2c896ada0f9188d 242 TIGRFAM TIGR02253 CTE7: HAD hydrolase, TIGR02253 family 1 221 4.2E-86 T 23-10-2018 IPR011950 HAD-superfamily hydrolase, subfamily IA, CTE7 GO:0016787 Reactome: R-HSA-4085001 TON_0817 5f0d8548a11cf9cff2c896ada0f9188d 242 Gene3D G3DSA:1.10.150.520 16 94 1.4E-86 T 23-10-2018 TON_0817 5f0d8548a11cf9cff2c896ada0f9188d 242 SUPERFAMILY SSF56784 1 225 2.49E-47 T 23-10-2018 IPR036412 HAD-like superfamily TON_0817 5f0d8548a11cf9cff2c896ada0f9188d 242 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 193 7.8E-33 T 23-10-2018 TON_1770 4e6f57da87f292afb4964cab682b4a13 253 SUPERFAMILY SSF52402 3 248 6.4E-79 T 23-10-2018 TON_1770 4e6f57da87f292afb4964cab682b4a13 253 Pfam PF02540 NAD synthase 9 248 6.6E-88 T 23-10-2018 IPR022310 NAD/GMP synthase TON_1770 4e6f57da87f292afb4964cab682b4a13 253 Hamap MF_00193 NH(3)-dependent NAD(+) synthetase [nadE]. 5 251 52.146 T 23-10-2018 IPR022926 NH(3)-dependent NAD(+) synthetase GO:0008795|GO:0009435 KEGG: 00760+6.3.1.5 TON_1770 4e6f57da87f292afb4964cab682b4a13 253 Gene3D G3DSA:3.40.50.620 4 253 4.2E-92 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TON_1770 4e6f57da87f292afb4964cab682b4a13 253 TIGRFAM TIGR00552 nadE: NAD+ synthetase 8 248 3.4E-84 T 23-10-2018 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 TON_1770 4e6f57da87f292afb4964cab682b4a13 253 ProSitePatterns PS00304 Small, acid-soluble spore proteins, alpha/beta type, signature 1. 217 226 - T 23-10-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 TON_1620 b23259e80fab5dd2ff307f243e729194 142 Pfam PF02391 MoaE protein 5 117 8.3E-37 T 23-10-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 TON_1620 b23259e80fab5dd2ff307f243e729194 142 Gene3D G3DSA:3.90.1170.40 1 136 3.8E-49 T 23-10-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 TON_1620 b23259e80fab5dd2ff307f243e729194 142 SUPERFAMILY SSF54690 3 135 3.79E-45 T 23-10-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 TON_0190 d29935503d1d80154b54d945870accb5 428 SUPERFAMILY SSF161070 11 363 1.24E-7 T 23-10-2018 IPR037272 Sodium:neurotransmitter symporter superfamily GO:0005328 TON_0106 dc1ad3896fe542a720a15eabeccff253 120 SUPERFAMILY SSF52080 5 119 5.23E-31 T 23-10-2018 IPR036227 Ribosomal L18e/L15P superfamily TON_0106 dc1ad3896fe542a720a15eabeccff253 120 Pfam PF17135 Ribosomal protein 60S L18 and 50S L18e 11 119 2.2E-16 T 23-10-2018 IPR021131 Ribosomal protein L18e/L15P TON_0106 dc1ad3896fe542a720a15eabeccff253 120 ProSitePatterns PS01106 Ribosomal protein L18e signature. 35 52 - T 23-10-2018 IPR021132 Ribosomal protein L18e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0106 dc1ad3896fe542a720a15eabeccff253 120 Gene3D G3DSA:3.100.10.10 5 120 1.0E-40 T 23-10-2018 TON_0106 dc1ad3896fe542a720a15eabeccff253 120 Hamap MF_00329 50S ribosomal protein L18e [rpl18e]. 4 120 30.893 T 23-10-2018 IPR022947 Ribosomal protein L18e, archaea TON_1078 acb22040580d989e08ace8a10523fdda 184 Pfam PF02545 Maf-like protein 2 175 2.1E-57 T 23-10-2018 IPR003697 Maf-like protein GO:0047429 TON_1078 acb22040580d989e08ace8a10523fdda 184 TIGRFAM TIGR00172 maf: septum formation protein Maf 2 175 2.0E-49 T 23-10-2018 IPR003697 Maf-like protein GO:0047429 TON_1078 acb22040580d989e08ace8a10523fdda 184 Hamap MF_00528 Septum formation protein Maf [maf]. 1 183 31.019 T 23-10-2018 IPR003697 Maf-like protein GO:0047429 TON_1078 acb22040580d989e08ace8a10523fdda 184 Gene3D G3DSA:3.90.950.10 1 180 1.0E-65 T 23-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like TON_1078 acb22040580d989e08ace8a10523fdda 184 PIRSF PIRSF006305 1 181 2.5E-60 T 23-10-2018 IPR003697 Maf-like protein GO:0047429 TON_1078 acb22040580d989e08ace8a10523fdda 184 SUPERFAMILY SSF52972 1 175 3.74E-58 T 23-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like TON_0778 1e056556aa319d0c326ee5ffb6b52c80 93 Gene3D G3DSA:3.30.70.930 1 93 1.7E-33 T 23-10-2018 IPR029756 MTH1187/YkoF-like TON_0778 1e056556aa319d0c326ee5ffb6b52c80 93 TIGRFAM TIGR00106 TIGR00106: uncharacterized protein, MTH1187 family 3 91 2.8E-28 T 23-10-2018 IPR002767 Thiamine-binding protein TON_0778 1e056556aa319d0c326ee5ffb6b52c80 93 SUPERFAMILY SSF89957 1 91 8.5E-30 T 23-10-2018 IPR029756 MTH1187/YkoF-like TON_0778 1e056556aa319d0c326ee5ffb6b52c80 93 Pfam PF01910 Thiamine-binding protein 4 91 1.5E-30 T 23-10-2018 IPR002767 Thiamine-binding protein TON_0290 9ce3fb7f85b29c9bee74e435536ab7b2 378 SUPERFAMILY SSF111331 99 178 9.29E-8 T 23-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily TON_0290 9ce3fb7f85b29c9bee74e435536ab7b2 378 PIRSF PIRSF016907 1 378 2.2E-149 T 23-10-2018 IPR011386 Putative ATP-NAD kinase TON_0290 9ce3fb7f85b29c9bee74e435536ab7b2 378 ProDom PD125086 DNA GP2 END PROTECTOR TERMINAL GP2-LIKE T4 ENDS PROTECTS PROTECTING 261 364 5.0E-5 T 23-10-2018 TON_0290 9ce3fb7f85b29c9bee74e435536ab7b2 378 Pfam PF01513 ATP-NAD kinase 2 377 6.3E-48 T 23-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 TON_0012 aef2c18f58d919a5b3f1d15248ed3b68 128 SUPERFAMILY SSF54637 13 119 5.03E-25 T 23-10-2018 IPR029069 HotDog domain superfamily TON_0012 aef2c18f58d919a5b3f1d15248ed3b68 128 Gene3D G3DSA:3.10.129.10 1 128 6.9E-43 T 23-10-2018 TON_0012 aef2c18f58d919a5b3f1d15248ed3b68 128 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 18 119 3.3E-11 T 23-10-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 TON_0012 aef2c18f58d919a5b3f1d15248ed3b68 128 Pfam PF03061 Thioesterase superfamily 40 112 1.1E-7 T 23-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 TON_0684 9662b4d0ec9b1ae1619dd77d10d2a03b 233 Hamap MF_00719 Adenosylcobinamide-GDP ribazoletransferase [cobS]. 1 233 28.882 T 23-10-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 TON_0684 9662b4d0ec9b1ae1619dd77d10d2a03b 233 TIGRFAM TIGR00317 cobS: cobalamin 5'-phosphate synthase 2 223 5.3E-45 T 23-10-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 TON_0684 9662b4d0ec9b1ae1619dd77d10d2a03b 233 Pfam PF02654 Cobalamin-5-phosphate synthase 5 221 2.8E-39 T 23-10-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 TON_1006 b5b8597eea5f735ffc2f6940d3d61426 196 Gene3D G3DSA:3.40.50.620 1 195 1.4E-58 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TON_1006 b5b8597eea5f735ffc2f6940d3d61426 196 SUPERFAMILY SSF52402 2 156 6.75E-40 T 23-10-2018 TON_1006 b5b8597eea5f735ffc2f6940d3d61426 196 Pfam PF02568 Thiamine biosynthesis protein (ThiI) 2 190 4.9E-60 T 23-10-2018 IPR020536 Thil, AANH domain GO:0004810 KEGG: 00730+2.8.1.4 TON_1563 c7dbe324c9297040a751e45b92dad104 711 PIRSF PIRSF000144 52 431 9.3E-65 T 23-10-2018 TON_1563 c7dbe324c9297040a751e45b92dad104 711 PIRSF PIRSF000144 506 691 0.12 T 23-10-2018 TON_1563 c7dbe324c9297040a751e45b92dad104 711 Pfam PF00384 Molybdopterin oxidoreductase 63 484 1.3E-90 T 23-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_1563 c7dbe324c9297040a751e45b92dad104 711 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 6 58 4.9E-9 T 23-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_1563 c7dbe324c9297040a751e45b92dad104 711 TIGRFAM TIGR01591 Fdh-alpha: formate dehydrogenase, alpha subunit 8 684 8.7E-240 T 23-10-2018 IPR006478 Formate dehydrogenase, alpha subunit GO:0008863|GO:0015942|GO:0055114 KEGG: 00630+1.17.1.9|KEGG: 00680+1.17.1.9|MetaCyc: PWY-1881|MetaCyc: PWY-5497|MetaCyc: PWY-6696|MetaCyc: PWY-7985 TON_1563 c7dbe324c9297040a751e45b92dad104 711 Gene3D G3DSA:3.40.50.740 72 534 1.6E-183 T 23-10-2018 TON_1563 c7dbe324c9297040a751e45b92dad104 711 SUPERFAMILY SSF53706 3 580 4.32E-209 T 23-10-2018 TON_1563 c7dbe324c9297040a751e45b92dad104 711 SUPERFAMILY SSF50692 531 687 1.24E-46 T 23-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily TON_1563 c7dbe324c9297040a751e45b92dad104 711 Pfam PF01568 Molydopterin dinucleotide binding domain 578 681 1.2E-29 T 23-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 TON_1563 c7dbe324c9297040a751e45b92dad104 711 SMART SM00926 3 60 9.7E-10 T 23-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_1563 c7dbe324c9297040a751e45b92dad104 711 Gene3D G3DSA:2.20.25.90 1 62 4.2E-10 T 23-10-2018 TON_1563 c7dbe324c9297040a751e45b92dad104 711 Gene3D G3DSA:3.40.228.10 140 338 1.6E-183 T 23-10-2018 TON_1563 c7dbe324c9297040a751e45b92dad104 711 Gene3D G3DSA:2.40.40.20 565 695 7.4E-43 T 23-10-2018 TON_0855 b4e6c8efdcbf910a4d4444a03f4a0c2d 179 Pfam PF00881 Nitroreductase family 63 150 1.5E-12 T 23-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 TON_0855 b4e6c8efdcbf910a4d4444a03f4a0c2d 179 Pfam PF00881 Nitroreductase family 7 62 4.1E-16 T 23-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 TON_0855 b4e6c8efdcbf910a4d4444a03f4a0c2d 179 Gene3D G3DSA:3.40.109.10 1 173 5.4E-52 T 23-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 TON_0855 b4e6c8efdcbf910a4d4444a03f4a0c2d 179 SUPERFAMILY SSF55469 1 159 6.54E-49 T 23-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 TON_1048 f19c67b0e0da1affd03781e98d6a3b2d 149 Pfam PF03684 Uncharacterised protein family (UPF0179) 9 144 7.2E-43 T 23-10-2018 IPR005369 Uncharacterised protein family UPF0179 TON_1048 f19c67b0e0da1affd03781e98d6a3b2d 149 PIRSF PIRSF006595 6 149 5.2E-51 T 23-10-2018 IPR005369 Uncharacterised protein family UPF0179 TON_1048 f19c67b0e0da1affd03781e98d6a3b2d 149 ProDom PD016182 UPF0179 TK0790 TV1250 PAE0681 PF1381 AF2154 MA3685 VNG1401C MJ1627 PH1477 8 148 1.0E-66 T 23-10-2018 IPR005369 Uncharacterised protein family UPF0179 TON_1048 f19c67b0e0da1affd03781e98d6a3b2d 149 Hamap MF_00498 UPF0179 protein . 7 146 24.161 T 23-10-2018 IPR005369 Uncharacterised protein family UPF0179 TON_1125 650b1228ab5feea66239c4f11078abaf 153 SUPERFAMILY SSF88723 28 68 7.06E-5 T 23-10-2018 IPR029060 PIN-like domain superfamily TON_1125 650b1228ab5feea66239c4f11078abaf 153 Pfam PF01927 Mut7-C RNAse domain 1 144 7.4E-43 T 23-10-2018 IPR002782 Mut7-C RNAse domain TON_1384 cce3c9a56f3542222cfa6e609aaa9740 158 Gene3D G3DSA:3.30.70.1890 1 121 8.3E-47 T 23-10-2018 TON_1384 cce3c9a56f3542222cfa6e609aaa9740 158 TIGRFAM TIGR01877 cas_cas6: CRISPR-associated endoribonuclease Cas6 50 139 5.1E-17 T 23-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 TON_1384 cce3c9a56f3542222cfa6e609aaa9740 158 Pfam PF01881 CRISPR associated protein Cas6 95 142 2.5E-7 T 23-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 TON_0254 60bc651ea7fcd0b2b222f0a48ac65745 258 Pfam PF00005 ABC transporter 19 163 2.0E-27 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TON_0254 60bc651ea7fcd0b2b222f0a48ac65745 258 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TON_0254 60bc651ea7fcd0b2b222f0a48ac65745 258 SMART SM00382 28 211 7.8E-14 T 23-10-2018 IPR003593 AAA+ ATPase domain TON_0254 60bc651ea7fcd0b2b222f0a48ac65745 258 SUPERFAMILY SSF52540 4 218 3.04E-56 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_0254 60bc651ea7fcd0b2b222f0a48ac65745 258 Gene3D G3DSA:3.40.50.300 3 244 6.9E-63 T 23-10-2018 TON_0416 067b6142966aac51399cdfe864de1662 240 Pfam PF01522 Polysaccharide deacetylase 4 125 6.5E-21 T 23-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 TON_0416 067b6142966aac51399cdfe864de1662 240 SUPERFAMILY SSF88713 3 232 7.79E-35 T 23-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 TON_0416 067b6142966aac51399cdfe864de1662 240 Gene3D G3DSA:3.20.20.370 1 239 7.6E-41 T 23-10-2018 TON_1909 9e74c5be156bea8a7f90ad288ca7720d 51 Pfam PF01599 Ribosomal protein S27a 5 46 6.6E-23 T 23-10-2018 IPR002906 Ribosomal protein S27a GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 TON_1909 9e74c5be156bea8a7f90ad288ca7720d 51 SUPERFAMILY SSF57829 4 50 1.83E-21 T 23-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 TON_1909 9e74c5be156bea8a7f90ad288ca7720d 51 Gene3D G3DSA:2.20.25.660 2 49 1.0E-19 T 23-10-2018 IPR038582 S27a-like superfamily Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 TON_1909 9e74c5be156bea8a7f90ad288ca7720d 51 SMART SM01402 4 46 3.5E-25 T 23-10-2018 IPR002906 Ribosomal protein S27a GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 TON_1909 9e74c5be156bea8a7f90ad288ca7720d 51 Hamap MF_00777 30S ribosomal protein S27ae [rps27ae]. 4 49 19.814 T 23-10-2018 IPR022845 Ribosomal protein S27ae TON_1282 51830c7c69b62c300485a20b751e6eee 494 Gene3D G3DSA:1.10.10.1100 399 475 2.8E-147 T 23-10-2018 TON_1282 51830c7c69b62c300485a20b751e6eee 494 Gene3D G3DSA:3.50.50.60 220 310 2.8E-147 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TON_1282 51830c7c69b62c300485a20b751e6eee 494 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 267 353 9.5E-8 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TON_1282 51830c7c69b62c300485a20b751e6eee 494 Gene3D G3DSA:3.50.50.60 110 481 2.8E-147 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TON_1282 51830c7c69b62c300485a20b751e6eee 494 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 13 88 1.7E-13 T 23-10-2018 TON_1282 51830c7c69b62c300485a20b751e6eee 494 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 208 226 2.6E-8 T 23-10-2018 TON_1282 51830c7c69b62c300485a20b751e6eee 494 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 111 130 2.6E-8 T 23-10-2018 TON_1282 51830c7c69b62c300485a20b751e6eee 494 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 302 318 2.6E-8 T 23-10-2018 TON_1282 51830c7c69b62c300485a20b751e6eee 494 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 110 132 3.9E-6 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TON_1282 51830c7c69b62c300485a20b751e6eee 494 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 209 217 3.9E-6 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TON_1282 51830c7c69b62c300485a20b751e6eee 494 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 248 272 3.9E-6 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TON_1282 51830c7c69b62c300485a20b751e6eee 494 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 110 258 1.6E-12 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TON_1282 51830c7c69b62c300485a20b751e6eee 494 SUPERFAMILY SSF51905 109 376 6.18E-26 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TON_1282 51830c7c69b62c300485a20b751e6eee 494 Gene3D G3DSA:3.10.20.440 1 95 1.2E-37 T 23-10-2018 TON_1836 33b7587ba2158646b057857429bb020e 317 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 241 1.9E-58 T 23-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 TON_1836 33b7587ba2158646b057857429bb020e 317 Gene3D G3DSA:3.90.25.10 180 224 1.3E-12 T 23-10-2018 TON_1836 33b7587ba2158646b057857429bb020e 317 Gene3D G3DSA:3.90.25.10 225 317 2.7E-27 T 23-10-2018 TON_1836 33b7587ba2158646b057857429bb020e 317 Gene3D G3DSA:3.40.50.720 1 179 1.1E-53 T 23-10-2018 TON_1836 33b7587ba2158646b057857429bb020e 317 SUPERFAMILY SSF51735 1 315 2.32E-88 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TON_1712 e5756b2d7ae20a3f02df194ad4f30df8 82 Pfam PF01998 Protein of unknown function DUF131 33 74 1.6E-12 T 23-10-2018 IPR002849 Protein of unknown function DUF131 TON_0212 73a2f51d9d31b16a3366da796452a819 428 SMART SM00770 1 254 1.2E-53 T 23-10-2018 IPR001531 Zinc-dependent phospholipase C GO:0004629|GO:0008270 KEGG: 00562+3.1.4.3|KEGG: 00564+3.1.4.3|KEGG: 00565+3.1.4.3|MetaCyc: PWY-7782|MetaCyc: PWY-7783 TON_0212 73a2f51d9d31b16a3366da796452a819 428 SUPERFAMILY SSF48537 29 259 3.43E-33 T 23-10-2018 IPR008947 Phospholipase C/P1 nuclease domain superfamily GO:0016788 TON_0212 73a2f51d9d31b16a3366da796452a819 428 Gene3D G3DSA:1.10.575.10 21 156 8.2E-13 T 23-10-2018 IPR008947 Phospholipase C/P1 nuclease domain superfamily GO:0016788 TON_0986 630c779a54dbfc0feccd13f8cf1f7ef7 199 Gene3D G3DSA:2.30.110.10 3 124 1.9E-9 T 23-10-2018 IPR012349 FMN-binding split barrel GO:0048037 TON_0986 630c779a54dbfc0feccd13f8cf1f7ef7 199 SUPERFAMILY SSF50475 4 189 7.06E-34 T 23-10-2018 TON_0986 630c779a54dbfc0feccd13f8cf1f7ef7 199 PIRSF PIRSF018747 1 192 5.8E-48 T 23-10-2018 IPR016733 Uncharacterised conserved protein UCP018747 TON_0986 630c779a54dbfc0feccd13f8cf1f7ef7 199 Pfam PF04289 Protein of unknown function (DUF447) 11 183 3.2E-23 T 23-10-2018 IPR007386 Protein of unknown function DUF447 TON_0518 f7159a716f47d810fd147785e57c8f3b 476 SUPERFAMILY SSF64182 6 470 2.93E-65 T 23-10-2018 IPR038763 DHH phosphoesterase superfamily TON_0518 f7159a716f47d810fd147785e57c8f3b 476 Pfam PF02272 DHHA1 domain 329 463 3.4E-20 T 23-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 TON_0518 f7159a716f47d810fd147785e57c8f3b 476 Gene3D G3DSA:3.10.310.30 336 467 2.3E-9 T 23-10-2018 TON_0518 f7159a716f47d810fd147785e57c8f3b 476 Gene3D G3DSA:3.90.1640.30 3 236 2.9E-22 T 23-10-2018 TON_1663 0700fa56090028d42812525daad4757d 191 SMART SM00418 11 105 4.9E-11 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TON_1663 0700fa56090028d42812525daad4757d 191 SUPERFAMILY SSF46785 1 165 2.07E-35 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TON_1663 0700fa56090028d42812525daad4757d 191 Gene3D G3DSA:1.10.20.10 90 191 1.1E-50 T 23-10-2018 IPR009072 Histone-fold GO:0046982 TON_1663 0700fa56090028d42812525daad4757d 191 Gene3D G3DSA:1.10.10.10 1 89 1.1E-31 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TON_1663 0700fa56090028d42812525daad4757d 191 Pfam PF12840 Helix-turn-helix domain 11 67 1.0E-15 T 23-10-2018 TON_1493 0b7304879c497a0c79bb49e1314a36d1 278 SUPERFAMILY SSF52402 151 276 5.53E-20 T 23-10-2018 TON_1493 0b7304879c497a0c79bb49e1314a36d1 278 Gene3D G3DSA:3.40.50.620 1 143 8.0E-28 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TON_1493 0b7304879c497a0c79bb49e1314a36d1 278 PRINTS PR01438 Universal stress protein signature 2 20 1.1E-17 T 23-10-2018 IPR006015 Universal stress protein A TON_1493 0b7304879c497a0c79bb49e1314a36d1 278 PRINTS PR01438 Universal stress protein signature 254 276 1.1E-17 T 23-10-2018 IPR006015 Universal stress protein A TON_1493 0b7304879c497a0c79bb49e1314a36d1 278 PRINTS PR01438 Universal stress protein signature 236 248 1.1E-17 T 23-10-2018 IPR006015 Universal stress protein A TON_1493 0b7304879c497a0c79bb49e1314a36d1 278 SUPERFAMILY SSF52402 1 133 1.51E-25 T 23-10-2018 TON_1493 0b7304879c497a0c79bb49e1314a36d1 278 Pfam PF00582 Universal stress protein family 193 276 1.1E-15 T 23-10-2018 IPR006016 UspA TON_1493 0b7304879c497a0c79bb49e1314a36d1 278 Pfam PF00582 Universal stress protein family 1 133 4.1E-18 T 23-10-2018 IPR006016 UspA TON_1493 0b7304879c497a0c79bb49e1314a36d1 278 Gene3D G3DSA:3.40.50.620 148 278 2.1E-22 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TON_0965 d012f18d58a1e2907acc4c199403cb15 170 TIGRFAM TIGR00288 TIGR00288: TIGR00288 family protein 6 160 7.2E-66 T 23-10-2018 IPR002790 Conserved hypothetical protein CHP00288 TON_0965 d012f18d58a1e2907acc4c199403cb15 170 Pfam PF01936 NYN domain 29 160 2.1E-21 T 23-10-2018 IPR021139 NYN domain, limkain-b1-type TON_0965 d012f18d58a1e2907acc4c199403cb15 170 Gene3D G3DSA:3.40.50.1010 19 162 1.9E-12 T 23-10-2018 TON_0965 d012f18d58a1e2907acc4c199403cb15 170 ProDom PD010896 FAMILY DUF88 ARCHAEBACTERIAL PROTEIN MJ0482 PH0073 PF2040 VNG1608C MA3857 PF2039 29 101 3.0E-31 T 23-10-2018 TON_1014 71e159708a1454639000998e7fd23ccc 297 SMART SM00493 5 84 5.0E-7 T 23-10-2018 IPR006171 TOPRIM domain TON_1014 71e159708a1454639000998e7fd23ccc 297 Gene3D G3DSA:3.40.1360.10 4 119 1.2E-6 T 23-10-2018 TON_1014 71e159708a1454639000998e7fd23ccc 297 Pfam PF01751 Toprim domain 8 87 8.0E-8 T 23-10-2018 IPR006171 TOPRIM domain TON_0707 21e4649647a5451fae67c837d27b7e8f 550 Gene3D G3DSA:3.30.260.10 147 405 9.4E-217 T 23-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily TON_0707 21e4649647a5451fae67c837d27b7e8f 550 ProSitePatterns PS00750 Chaperonins TCP-1 signature 1. 40 52 - T 23-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 TON_0707 21e4649647a5451fae67c837d27b7e8f 550 Gene3D G3DSA:1.10.560.10 28 522 9.4E-217 T 23-10-2018 IPR027413 GroEL-like equatorial domain superfamily TON_0707 21e4649647a5451fae67c837d27b7e8f 550 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 59 77 1.6E-34 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 TON_0707 21e4649647a5451fae67c837d27b7e8f 550 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 37 53 1.6E-34 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 TON_0707 21e4649647a5451fae67c837d27b7e8f 550 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 89 108 1.6E-34 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 TON_0707 21e4649647a5451fae67c837d27b7e8f 550 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 407 419 1.6E-34 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 TON_0707 21e4649647a5451fae67c837d27b7e8f 550 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 373 395 1.6E-34 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 TON_0707 21e4649647a5451fae67c837d27b7e8f 550 SUPERFAMILY SSF54849 149 405 1.1E-31 T 23-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily TON_0707 21e4649647a5451fae67c837d27b7e8f 550 TIGRFAM TIGR02339 thermosome_arch: thermosome, various subunits, archaeal 8 525 4.4E-236 T 23-10-2018 IPR012714 Thermosome, archaeal GO:0005524|GO:0006457|GO:0051082 TON_0707 21e4649647a5451fae67c837d27b7e8f 550 ProSitePatterns PS00995 Chaperonins TCP-1 signature 3. 89 97 - T 23-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 TON_0707 21e4649647a5451fae67c837d27b7e8f 550 ProSitePatterns PS00751 Chaperonins TCP-1 signature 2. 61 77 - T 23-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 TON_0707 21e4649647a5451fae67c837d27b7e8f 550 SUPERFAMILY SSF48592 17 523 5.63E-92 T 23-10-2018 IPR027413 GroEL-like equatorial domain superfamily TON_0707 21e4649647a5451fae67c837d27b7e8f 550 SUPERFAMILY SSF52029 212 378 6.63E-62 T 23-10-2018 IPR027409 GroEL-like apical domain superfamily TON_0707 21e4649647a5451fae67c837d27b7e8f 550 Pfam PF00118 TCP-1/cpn60 chaperonin family 35 525 1.1E-182 T 23-10-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 TON_0707 21e4649647a5451fae67c837d27b7e8f 550 Gene3D G3DSA:3.50.7.10 218 369 9.4E-217 T 23-10-2018 IPR027409 GroEL-like apical domain superfamily TON_0984 7fdf4461635fed9b5e8a9063a8fddf94 614 SUPERFAMILY SSF161098 334 607 5.7E-41 T 23-10-2018 IPR035906 MetI-like superfamily TON_0984 7fdf4461635fed9b5e8a9063a8fddf94 614 SUPERFAMILY SSF161098 23 313 3.92E-43 T 23-10-2018 IPR035906 MetI-like superfamily TON_0984 7fdf4461635fed9b5e8a9063a8fddf94 614 Gene3D G3DSA:1.10.3720.10 79 318 2.5E-51 T 23-10-2018 IPR035906 MetI-like superfamily TON_0984 7fdf4461635fed9b5e8a9063a8fddf94 614 Gene3D G3DSA:1.10.3720.10 331 601 6.8E-37 T 23-10-2018 IPR035906 MetI-like superfamily TON_0984 7fdf4461635fed9b5e8a9063a8fddf94 614 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 117 306 2.3E-12 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TON_0984 7fdf4461635fed9b5e8a9063a8fddf94 614 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 420 603 1.2E-15 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TON_0815 9156253d62390dd8f26a8f32ac0f1a0f 85 Pfam PF01925 Sulfite exporter TauE/SafE 1 76 1.1E-11 T 23-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 TON_0525 a513b9514f3289b7eded3876e9f84965 125 Gene3D G3DSA:1.10.10.10 12 122 2.1E-24 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TON_0525 a513b9514f3289b7eded3876e9f84965 125 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 93 108 1.4E-17 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TON_0525 a513b9514f3289b7eded3876e9f84965 125 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 78 93 1.4E-17 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TON_0525 a513b9514f3289b7eded3876e9f84965 125 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 65 76 1.4E-17 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TON_0525 a513b9514f3289b7eded3876e9f84965 125 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 46 61 1.4E-17 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TON_0525 a513b9514f3289b7eded3876e9f84965 125 SUPERFAMILY SSF46785 40 116 5.31E-22 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TON_0525 a513b9514f3289b7eded3876e9f84965 125 Pfam PF01022 Bacterial regulatory protein, arsR family 51 95 1.1E-12 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TON_0525 a513b9514f3289b7eded3876e9f84965 125 SMART SM00418 44 122 8.8E-26 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TON_0615 9cf1bb566ca8d4f2f3babc1bc3ceca5a 349 Pfam PF00535 Glycosyl transferase family 2 40 200 4.8E-39 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TON_0615 9cf1bb566ca8d4f2f3babc1bc3ceca5a 349 Gene3D G3DSA:3.90.550.10 28 247 4.5E-51 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TON_0615 9cf1bb566ca8d4f2f3babc1bc3ceca5a 349 SUPERFAMILY SSF53448 36 291 1.01E-58 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TON_1295 9298338dbf32fa8ee09c6df470b9ede3 418 Gene3D G3DSA:3.90.1150.10 34 409 4.2E-163 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TON_1295 9298338dbf32fa8ee09c6df470b9ede3 418 SUPERFAMILY SSF53383 15 411 3.13E-120 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TON_1295 9298338dbf32fa8ee09c6df470b9ede3 418 Gene3D G3DSA:3.40.640.10 79 304 4.2E-163 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TON_1295 9298338dbf32fa8ee09c6df470b9ede3 418 Pfam PF00155 Aminotransferase class I and II 55 405 6.1E-39 T 23-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 TON_0521 9c76ec81ebe5b60f6fd277e691d0bb86 351 SUPERFAMILY SSF75217 187 334 4.91E-21 T 23-10-2018 IPR029028 Alpha/beta knot methyltransferases TON_0521 9c76ec81ebe5b60f6fd277e691d0bb86 351 Gene3D G3DSA:3.30.2130.30 1 150 1.6E-22 T 23-10-2018 TON_0521 9c76ec81ebe5b60f6fd277e691d0bb86 351 Pfam PF14419 AF2226-like SPOUT RNA Methylase fused to THUMP 169 342 2.3E-82 T 23-10-2018 IPR025849 AF2226-like SPOUT RNA methylase fused to THUMP TON_0521 9c76ec81ebe5b60f6fd277e691d0bb86 351 SMART SM00981 60 149 2.2E-21 T 23-10-2018 IPR004114 THUMP domain GO:0003723 TON_0521 9c76ec81ebe5b60f6fd277e691d0bb86 351 Pfam PF02926 THUMP domain 33 148 2.2E-27 T 23-10-2018 IPR004114 THUMP domain GO:0003723 TON_0521 9c76ec81ebe5b60f6fd277e691d0bb86 351 SUPERFAMILY SSF143437 7 147 1.05E-25 T 23-10-2018 TON_0523 1701472cfd63c10b4b3e0a701e57ce21 149 SUPERFAMILY SSF46785 5 65 1.87E-14 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TON_0523 1701472cfd63c10b4b3e0a701e57ce21 149 Gene3D G3DSA:1.10.10.10 1 56 1.2E-19 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TON_0523 1701472cfd63c10b4b3e0a701e57ce21 149 SUPERFAMILY SSF54909 67 146 1.0E-6 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel TON_0523 1701472cfd63c10b4b3e0a701e57ce21 149 Pfam PF13412 Winged helix-turn-helix DNA-binding 6 52 1.4E-15 T 23-10-2018 TON_0523 1701472cfd63c10b4b3e0a701e57ce21 149 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 5 21 6.1E-11 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TON_0523 1701472cfd63c10b4b3e0a701e57ce21 149 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 21 32 6.1E-11 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TON_0523 1701472cfd63c10b4b3e0a701e57ce21 149 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 32 51 6.1E-11 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TON_0523 1701472cfd63c10b4b3e0a701e57ce21 149 Gene3D G3DSA:3.30.70.920 57 149 2.4E-29 T 23-10-2018 TON_0523 1701472cfd63c10b4b3e0a701e57ce21 149 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 36 51 7.7E-5 T 23-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 TON_0523 1701472cfd63c10b4b3e0a701e57ce21 149 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 20 36 7.7E-5 T 23-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 TON_0523 1701472cfd63c10b4b3e0a701e57ce21 149 SMART SM00344 5 111 1.0E-23 T 23-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 TON_0236 d3f77106d8f23fc04d840456fc63827c 65 ProSitePatterns PS01168 Ribosomal protein S27e signature. 19 51 - T 23-10-2018 IPR000592 Ribosomal protein S27e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0236 d3f77106d8f23fc04d840456fc63827c 65 Gene3D G3DSA:2.20.25.100 11 65 6.4E-25 T 23-10-2018 IPR023407 Ribosomal protein S27e, zinc-binding domain superfamily TON_0236 d3f77106d8f23fc04d840456fc63827c 65 Pfam PF01667 Ribosomal protein S27 11 64 2.3E-26 T 23-10-2018 IPR000592 Ribosomal protein S27e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0236 d3f77106d8f23fc04d840456fc63827c 65 SUPERFAMILY SSF57829 11 65 3.66E-19 T 23-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 TON_0236 d3f77106d8f23fc04d840456fc63827c 65 Hamap MF_00371 30S ribosomal protein S27e [rps27e]. 5 64 22.447 T 23-10-2018 IPR000592 Ribosomal protein S27e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0397 b6620888109f32fe053c5c057c64e07c 350 TIGRFAM TIGR00692 tdh: L-threonine 3-dehydrogenase 7 346 8.5E-180 T 23-10-2018 IPR004627 L-threonine 3-dehydrogenase GO:0006567|GO:0008270|GO:0008743|GO:0055114 KEGG: 00260+1.1.1.103|MetaCyc: PWY-7378 TON_0397 b6620888109f32fe053c5c057c64e07c 350 Gene3D G3DSA:3.90.180.10 21 338 9.0E-134 T 23-10-2018 TON_0397 b6620888109f32fe053c5c057c64e07c 350 SMART SM00829 16 345 9.4E-6 T 23-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 TON_0397 b6620888109f32fe053c5c057c64e07c 350 SUPERFAMILY SSF51735 146 310 1.45E-34 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TON_0397 b6620888109f32fe053c5c057c64e07c 350 SUPERFAMILY SSF50129 3 177 4.72E-54 T 23-10-2018 IPR011032 GroES-like superfamily TON_0397 b6620888109f32fe053c5c057c64e07c 350 Gene3D G3DSA:3.40.50.720 157 291 9.0E-134 T 23-10-2018 TON_0397 b6620888109f32fe053c5c057c64e07c 350 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 66 80 - T 23-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 TON_0397 b6620888109f32fe053c5c057c64e07c 350 Pfam PF00107 Zinc-binding dehydrogenase 178 306 3.7E-30 T 23-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 TON_0397 b6620888109f32fe053c5c057c64e07c 350 Hamap MF_00627 L-threonine 3-dehydrogenase [tdh]. 5 347 54.187 T 23-10-2018 IPR004627 L-threonine 3-dehydrogenase GO:0006567|GO:0008270|GO:0008743|GO:0055114 KEGG: 00260+1.1.1.103|MetaCyc: PWY-7378 TON_0397 b6620888109f32fe053c5c057c64e07c 350 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 138 8.9E-36 T 23-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 TON_1430 de7051d0663f39ded69f4d552646b447 262 Gene3D G3DSA:3.40.830.10 1 261 4.2E-71 T 23-10-2018 TON_1430 de7051d0663f39ded69f4d552646b447 262 SUPERFAMILY SSF53213 5 258 1.27E-26 T 23-10-2018 TON_1430 de7051d0663f39ded69f4d552646b447 262 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 8 257 2.1E-15 T 23-10-2018 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 TON_0805 ecbfae1711594917de2f31faa7cf4240 440 SUPERFAMILY SSF111283 3 436 1.57E-95 T 23-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 TON_0805 ecbfae1711594917de2f31faa7cf4240 440 Gene3D G3DSA:3.30.2290.10 3 209 6.7E-17 T 23-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal TON_0805 ecbfae1711594917de2f31faa7cf4240 440 Pfam PF01523 Putative modulator of DNA gyrase 23 303 3.5E-50 T 23-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 TON_1000 88f908cd5c0d1a5af571785060ebaa8f 250 SUPERFAMILY SSF51658 10 249 1.57E-47 T 23-10-2018 IPR036237 Xylose isomerase-like superfamily TON_1000 88f908cd5c0d1a5af571785060ebaa8f 250 Pfam PF01261 Xylose isomerase-like TIM barrel 20 215 5.9E-36 T 23-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain TON_1000 88f908cd5c0d1a5af571785060ebaa8f 250 Gene3D G3DSA:3.20.20.150 2 250 1.4E-61 T 23-10-2018 TON_1000 88f908cd5c0d1a5af571785060ebaa8f 250 SMART SM00518 1 250 0.0022 T 23-10-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 TON_1336 1d9c0fc9ae724b1ea3f891ca62a1d7c3 483 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 159 457 6.3E-39 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TON_1336 1d9c0fc9ae724b1ea3f891ca62a1d7c3 483 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 298 316 5.1E-24 T 23-10-2018 TON_1336 1d9c0fc9ae724b1ea3f891ca62a1d7c3 483 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 400 416 5.1E-24 T 23-10-2018 TON_1336 1d9c0fc9ae724b1ea3f891ca62a1d7c3 483 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 160 179 5.1E-24 T 23-10-2018 TON_1336 1d9c0fc9ae724b1ea3f891ca62a1d7c3 483 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 426 448 5.1E-24 T 23-10-2018 TON_1336 1d9c0fc9ae724b1ea3f891ca62a1d7c3 483 SUPERFAMILY SSF46548 7 168 3.45E-31 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 TON_1336 1d9c0fc9ae724b1ea3f891ca62a1d7c3 483 Gene3D G3DSA:3.50.50.60 294 483 7.1E-30 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TON_1336 1d9c0fc9ae724b1ea3f891ca62a1d7c3 483 Gene3D G3DSA:3.50.50.60 154 290 2.7E-38 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TON_1336 1d9c0fc9ae724b1ea3f891ca62a1d7c3 483 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 441 448 2.3E-17 T 23-10-2018 TON_1336 1d9c0fc9ae724b1ea3f891ca62a1d7c3 483 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 401 415 2.3E-17 T 23-10-2018 TON_1336 1d9c0fc9ae724b1ea3f891ca62a1d7c3 483 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 159 181 2.3E-17 T 23-10-2018 TON_1336 1d9c0fc9ae724b1ea3f891ca62a1d7c3 483 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 298 323 2.3E-17 T 23-10-2018 TON_1336 1d9c0fc9ae724b1ea3f891ca62a1d7c3 483 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 23 140 1.4E-38 T 23-10-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 TON_1336 1d9c0fc9ae724b1ea3f891ca62a1d7c3 483 SUPERFAMILY SSF51971 157 408 2.3E-70 T 23-10-2018 TON_1336 1d9c0fc9ae724b1ea3f891ca62a1d7c3 483 Gene3D G3DSA:1.10.1060.10 4 152 3.3E-39 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 TON_1336 1d9c0fc9ae724b1ea3f891ca62a1d7c3 483 TIGRFAM TIGR01316 gltA: glutamate synthase (NADPH), homotetrameric 18 472 4.5E-207 T 23-10-2018 IPR006004 Glutamate synthase (NADPH), homotetrameric KEGG: 00195+1.18.1.2|MetaCyc: PWY-101 TON_0608 43e2f092c6b17bb949db461ae8fe00e5 388 Pfam PF00925 GTP cyclohydrolase II 201 360 3.6E-66 T 23-10-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 TON_0608 43e2f092c6b17bb949db461ae8fe00e5 388 Gene3D G3DSA:3.40.50.10990 196 361 8.5E-68 T 23-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 TON_0608 43e2f092c6b17bb949db461ae8fe00e5 388 Hamap MF_00179 GTP cyclohydrolase-2 [ribA]. 194 386 37.638 T 23-10-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 TON_0608 43e2f092c6b17bb949db461ae8fe00e5 388 PIRSF PIRSF001259 2 388 1.3E-122 T 23-10-2018 TON_0608 43e2f092c6b17bb949db461ae8fe00e5 388 SUPERFAMILY SSF142695 195 362 7.85E-58 T 23-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 TON_0608 43e2f092c6b17bb949db461ae8fe00e5 388 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 8 187 9.1E-41 T 23-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TON_0608 43e2f092c6b17bb949db461ae8fe00e5 388 SUPERFAMILY SSF55821 5 187 1.35E-44 T 23-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily TON_0608 43e2f092c6b17bb949db461ae8fe00e5 388 Gene3D G3DSA:3.90.870.10 4 195 1.0E-41 T 23-10-2018 TON_0608 43e2f092c6b17bb949db461ae8fe00e5 388 TIGRFAM TIGR00505 ribA: GTP cyclohydrolase II 200 384 5.3E-69 T 23-10-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 TON_1465 f10e0aa208db965ae8f5117c355247f9 299 SUPERFAMILY SSF48179 172 295 1.16E-27 T 23-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 TON_1465 f10e0aa208db965ae8f5117c355247f9 299 Pfam PF02558 Ketopantoate reductase PanE/ApbA 3 146 2.9E-37 T 23-10-2018 IPR013332 Ketopantoate reductase, N-terminal domain TON_1465 f10e0aa208db965ae8f5117c355247f9 299 Gene3D G3DSA:3.40.50.720 1 171 1.2E-64 T 23-10-2018 TON_1465 f10e0aa208db965ae8f5117c355247f9 299 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 2 297 1.6E-82 T 23-10-2018 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0008677|GO:0015940 KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 TON_1465 f10e0aa208db965ae8f5117c355247f9 299 SUPERFAMILY SSF51735 1 149 2.28E-21 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TON_1465 f10e0aa208db965ae8f5117c355247f9 299 Gene3D G3DSA:1.10.1040.10 172 296 1.7E-41 T 23-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 TON_1465 f10e0aa208db965ae8f5117c355247f9 299 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 172 295 3.8E-31 T 23-10-2018 IPR013752 Ketopantoate reductase, C-terminal domain TON_0336 50701ae4c15d1006df4b2050ee7bd74e 406 TIGRFAM TIGR03128 RuMP_HxlA: 3-hexulose-6-phosphate synthase 3 206 3.2E-82 T 23-10-2018 IPR017553 3-hexulose-6-phosphate synthase GO:0005975|GO:0043801 KEGG: 00030+4.1.2.43|KEGG: 00680+4.1.2.43|MetaCyc: PWY-1861|MetaCyc: PWY-7796 TON_0336 50701ae4c15d1006df4b2050ee7bd74e 406 TIGRFAM TIGR03127 RuMP_HxlB: 6-phospho 3-hexuloisomerase 219 406 9.3E-76 T 23-10-2018 IPR017552 3-hexulose-6-phosphate isomerase GO:0016853 TON_0336 50701ae4c15d1006df4b2050ee7bd74e 406 SUPERFAMILY SSF53697 215 404 2.63E-41 T 23-10-2018 TON_0336 50701ae4c15d1006df4b2050ee7bd74e 406 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 3 203 1.2E-27 T 23-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TON_0336 50701ae4c15d1006df4b2050ee7bd74e 406 SUPERFAMILY SSF51366 2 214 3.13E-44 T 23-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 TON_0336 50701ae4c15d1006df4b2050ee7bd74e 406 SMART SM00934 2 203 2.4E-45 T 23-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TON_0336 50701ae4c15d1006df4b2050ee7bd74e 406 Gene3D G3DSA:3.40.50.10490 213 406 1.7E-60 T 23-10-2018 TON_0336 50701ae4c15d1006df4b2050ee7bd74e 406 Pfam PF01380 SIS domain 246 347 3.4E-21 T 23-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 TON_0336 50701ae4c15d1006df4b2050ee7bd74e 406 Gene3D G3DSA:3.20.20.70 1 208 1.4E-74 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TON_0164 784a9acf8da5d83d37245fffa59031d5 203 TIGRFAM TIGR03634 arc_protsome_B: proteasome endopeptidase complex, archaeal, beta subunit 7 190 5.2E-79 T 23-10-2018 IPR019983 Peptidase T1A, proteasome beta-subunit, archaeal GO:0004175|GO:0005839|GO:0051603 TON_0164 784a9acf8da5d83d37245fffa59031d5 203 ProSitePatterns PS00854 Proteasome beta-type subunits signature. 11 58 - T 23-10-2018 IPR016050 Proteasome beta-type subunit, conserved site GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 TON_0164 784a9acf8da5d83d37245fffa59031d5 203 SUPERFAMILY SSF56235 5 202 1.3E-64 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TON_0164 784a9acf8da5d83d37245fffa59031d5 203 Hamap MF_02113_A Proteasome subunit beta [prcB]. 3 197 35.878 T 23-10-2018 IPR019983 Peptidase T1A, proteasome beta-subunit, archaeal GO:0004175|GO:0005839|GO:0051603 TON_0164 784a9acf8da5d83d37245fffa59031d5 203 PRINTS PR00141 Proteasome component signature 135 146 1.6E-9 T 23-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 TON_0164 784a9acf8da5d83d37245fffa59031d5 203 PRINTS PR00141 Proteasome component signature 15 30 1.6E-9 T 23-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 TON_0164 784a9acf8da5d83d37245fffa59031d5 203 PRINTS PR00141 Proteasome component signature 146 157 1.6E-9 T 23-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 TON_0164 784a9acf8da5d83d37245fffa59031d5 203 PRINTS PR00141 Proteasome component signature 171 182 1.6E-9 T 23-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 TON_0164 784a9acf8da5d83d37245fffa59031d5 203 Gene3D G3DSA:3.60.20.10 3 203 1.3E-68 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TON_0164 784a9acf8da5d83d37245fffa59031d5 203 Pfam PF00227 Proteasome subunit 6 185 6.2E-55 T 23-10-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 TON_1349 9c025d71f2cb714e4bdb3e8b6cede300 68 SMART SM00530 4 59 6.3E-21 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TON_1349 9c025d71f2cb714e4bdb3e8b6cede300 68 SUPERFAMILY SSF47413 3 64 1.74E-20 T 23-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TON_1349 9c025d71f2cb714e4bdb3e8b6cede300 68 Gene3D G3DSA:1.10.260.40 1 64 1.5E-31 T 23-10-2018 TON_1349 9c025d71f2cb714e4bdb3e8b6cede300 68 Pfam PF01381 Helix-turn-helix 5 57 2.7E-20 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TON_1353 a17cdbc06eafa5c9cf307c8c6bb75235 375 Pfam PF13186 Iron-sulfur cluster-binding domain 252 330 3.7E-16 T 23-10-2018 IPR023885 4Fe4S-binding SPASM domain TON_1353 a17cdbc06eafa5c9cf307c8c6bb75235 375 TIGRFAM TIGR04317 W_rSAM_matur: tungsten cofactor oxidoreducase radical SAM maturase 22 365 6.8E-153 T 23-10-2018 IPR027604 Tungsten cofactor oxidoreducase radical SAM maturase TON_1353 a17cdbc06eafa5c9cf307c8c6bb75235 375 Pfam PF13353 4Fe-4S single cluster domain 31 117 3.4E-6 T 23-10-2018 TON_1353 a17cdbc06eafa5c9cf307c8c6bb75235 375 SUPERFAMILY SSF102114 24 335 1.12E-52 T 23-10-2018 TON_1353 a17cdbc06eafa5c9cf307c8c6bb75235 375 Pfam PF04055 Radical SAM superfamily 28 188 9.4E-17 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TON_1353 a17cdbc06eafa5c9cf307c8c6bb75235 375 SMART SM00729 24 235 0.0014 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TON_1353 a17cdbc06eafa5c9cf307c8c6bb75235 375 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 30 41 - T 23-10-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TON_1129 beccae0254e06eb68063b9edc6ac9aba 127 Gene3D G3DSA:1.10.3730.10 45 127 3.0E-17 T 23-10-2018 TON_1129 beccae0254e06eb68063b9edc6ac9aba 127 SUPERFAMILY SSF48179 42 127 3.4E-18 T 23-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 TON_1129 beccae0254e06eb68063b9edc6ac9aba 127 Gene3D G3DSA:3.40.50.720 1 44 1.0E-7 T 23-10-2018 TON_1129 beccae0254e06eb68063b9edc6ac9aba 127 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 42 127 6.5E-18 T 23-10-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 TON_1002 aee5583260c8c215b3ab7fff6e1bfd54 241 Pfam PF13549 ATP-grasp domain 12 234 4.8E-82 T 23-10-2018 TON_1002 aee5583260c8c215b3ab7fff6e1bfd54 241 SUPERFAMILY SSF56059 19 236 1.26E-45 T 23-10-2018 TON_1002 aee5583260c8c215b3ab7fff6e1bfd54 241 Gene3D G3DSA:3.30.1490.20 38 115 1.0E-92 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 TON_1002 aee5583260c8c215b3ab7fff6e1bfd54 241 Gene3D G3DSA:3.30.470.20 17 232 1.0E-92 T 23-10-2018 TON_0297 4b2917400f88959473c7ac5e9b4f7c53 314 Pfam PF01032 FecCD transport family 9 307 9.6E-85 T 23-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 TON_0297 4b2917400f88959473c7ac5e9b4f7c53 314 SUPERFAMILY SSF81345 4 307 5.49E-76 T 23-10-2018 IPR037294 ABC transporter, BtuC-like TON_0297 4b2917400f88959473c7ac5e9b4f7c53 314 Gene3D G3DSA:1.10.3470.10 1 313 6.1E-97 T 23-10-2018 IPR037294 ABC transporter, BtuC-like TON_1516 85ebe97f444b9144c3d1bdae9d5c23fa 300 SUPERFAMILY SSF54211 1 156 9.11E-13 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TON_1516 85ebe97f444b9144c3d1bdae9d5c23fa 300 Pfam PF00288 GHMP kinases N terminal domain 93 151 1.3E-7 T 23-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 TON_1516 85ebe97f444b9144c3d1bdae9d5c23fa 300 PIRSF PIRSF016896 1 295 1.5E-90 T 23-10-2018 IPR012043 Pantoate kinase KEGG: 00770+2.7.1.169|MetaCyc: PWY-6654 TON_1773 8ea188481174c013bfaae671631a2ca8 135 PIRSF PIRSF005264 1 135 3.0E-43 T 23-10-2018 IPR002746 Uncharacterised protein family UPF0216 TON_1773 8ea188481174c013bfaae671631a2ca8 135 Pfam PF01886 Protein of unknown function DUF61 6 132 2.3E-35 T 23-10-2018 IPR002746 Uncharacterised protein family UPF0216 TON_1773 8ea188481174c013bfaae671631a2ca8 135 Hamap MF_00585 UPF0216 protein . 4 135 26.973 T 23-10-2018 IPR002746 Uncharacterised protein family UPF0216 TON_1773 8ea188481174c013bfaae671631a2ca8 135 ProDom PD016056 UPF0216 PYRAB16100 PH0358 MTH949 MK1676 AF0460 PF0452 MJ1224 8 132 1.0E-39 T 23-10-2018 IPR002746 Uncharacterised protein family UPF0216 TON_0816 5712fb4003a1414aa118d7c9a8d22d86 193 SUPERFAMILY SSF88697 9 112 3.6E-20 T 23-10-2018 IPR015947 PUA-like superfamily TON_0816 5712fb4003a1414aa118d7c9a8d22d86 193 Pfam PF04266 ASCH domain 15 112 2.4E-20 T 23-10-2018 IPR007374 ASCH domain TON_0816 5712fb4003a1414aa118d7c9a8d22d86 193 SMART SM01022 12 113 2.3E-20 T 23-10-2018 IPR007374 ASCH domain TON_0656 5d0dc98b74dd698e78099ebbf7250413 75 Gene3D G3DSA:2.30.30.90 13 75 2.1E-19 T 23-10-2018 IPR038157 Ferrous iron transporter, core domain TON_0656 5d0dc98b74dd698e78099ebbf7250413 75 SMART SM00899 3 74 4.6E-18 T 23-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 TON_0656 5d0dc98b74dd698e78099ebbf7250413 75 SUPERFAMILY SSF50037 5 74 2.06E-15 T 23-10-2018 IPR008988 Transcriptional repressor, C-terminal TON_0656 5d0dc98b74dd698e78099ebbf7250413 75 Pfam PF04023 FeoA domain 3 73 4.1E-16 T 23-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 TON_1247 16764e1e464f5ba9ced9f971b9c314dd 225 Gene3D G3DSA:3.90.1490.10 137 225 1.7E-32 T 23-10-2018 TON_1247 16764e1e464f5ba9ced9f971b9c314dd 225 Pfam PF01902 Diphthamide synthase 1 220 9.9E-88 T 23-10-2018 IPR002761 Diphthamide synthase domain MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 TON_1247 16764e1e464f5ba9ced9f971b9c314dd 225 Gene3D G3DSA:3.40.50.620 1 135 1.9E-48 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TON_1247 16764e1e464f5ba9ced9f971b9c314dd 225 TIGRFAM TIGR00289 TIGR00289: TIGR00289 family protein 1 222 3.7E-94 T 23-10-2018 IPR005237 Uncharacterised protein MJ0570 TON_1247 16764e1e464f5ba9ced9f971b9c314dd 225 TIGRFAM TIGR00290 MJ0570_dom: MJ0570-related uncharacterized domain 1 220 7.0E-86 T 23-10-2018 IPR002761 Diphthamide synthase domain MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 TON_1247 16764e1e464f5ba9ced9f971b9c314dd 225 PIRSF PIRSF039123 1 225 1.1E-82 T 23-10-2018 IPR030662 Diphthine--ammonia ligase/Uncharacterised protein MJ0570 MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 TON_1247 16764e1e464f5ba9ced9f971b9c314dd 225 SUPERFAMILY SSF52402 1 220 2.79E-75 T 23-10-2018 TON_1247 16764e1e464f5ba9ced9f971b9c314dd 225 TIGRFAM TIGR03679 arCOG00187: arCOG00187 universal archaeal metal-binding-domain/4Fe-4S-binding-domain containing ABC transporter, ATP-binding protein 4 216 1.3E-88 T 23-10-2018 IPR022427 Uncharacterised protein MJ0570, ATP-binding TON_0653 c3be71cac3d84c6c0f92e46d7d8bd75c 332 Gene3D G3DSA:3.30.1330.10 4 146 1.4E-23 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily TON_0653 c3be71cac3d84c6c0f92e46d7d8bd75c 332 PIRSF PIRSF005644 2 328 6.7E-64 T 23-10-2018 IPR011854 Carbamoyl dehydratase HypE TON_0653 c3be71cac3d84c6c0f92e46d7d8bd75c 332 Gene3D G3DSA:3.90.650.10 152 325 1.5E-32 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily TON_0653 c3be71cac3d84c6c0f92e46d7d8bd75c 332 Pfam PF02769 AIR synthase related protein, C-terminal domain 154 307 2.5E-18 T 23-10-2018 IPR010918 PurM-like, C-terminal domain TON_0653 c3be71cac3d84c6c0f92e46d7d8bd75c 332 SUPERFAMILY SSF55326 6 147 9.94E-22 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily TON_0653 c3be71cac3d84c6c0f92e46d7d8bd75c 332 Pfam PF00586 AIR synthase related protein, N-terminal domain 42 143 3.5E-14 T 23-10-2018 IPR016188 PurM-like, N-terminal domain TON_0653 c3be71cac3d84c6c0f92e46d7d8bd75c 332 SUPERFAMILY SSF56042 152 315 5.23E-30 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily TON_0415 f3e6b878e69934c8dbdf5f701870a0c3 348 Pfam PF13353 4Fe-4S single cluster domain 75 165 4.0E-5 T 23-10-2018 TON_0415 f3e6b878e69934c8dbdf5f701870a0c3 348 PIRSF PIRSF004869 1 313 1.4E-98 T 23-10-2018 IPR016431 Pyruvate-formate lyase-activating enzyme, predicted TON_0415 f3e6b878e69934c8dbdf5f701870a0c3 348 Pfam PF04055 Radical SAM superfamily 79 234 1.4E-20 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TON_0415 f3e6b878e69934c8dbdf5f701870a0c3 348 SMART SM00729 72 278 0.0032 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TON_0415 f3e6b878e69934c8dbdf5f701870a0c3 348 Gene3D G3DSA:3.20.20.70 63 286 9.1E-37 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TON_0415 f3e6b878e69934c8dbdf5f701870a0c3 348 SUPERFAMILY SSF102114 57 315 1.39E-34 T 23-10-2018 TON_0415 f3e6b878e69934c8dbdf5f701870a0c3 348 TIGRFAM TIGR04337 AmmeMemoSam_rS: AmmeMemoRadiSam system radical SAM enzyme 5 345 7.2E-114 T 23-10-2018 IPR027596 AmmeMemoRadiSam system radical SAM enzyme TON_1732 7a8795e8b839bebf305228d5e042d347 251 Gene3D G3DSA:3.40.1390.30 97 222 3.6E-76 T 23-10-2018 TON_1732 7a8795e8b839bebf305228d5e042d347 251 Gene3D G3DSA:3.40.1390.30 7 238 3.6E-76 T 23-10-2018 TON_1732 7a8795e8b839bebf305228d5e042d347 251 TIGRFAM TIGR00486 YbgI_SA1388: dinuclear metal center protein, YbgI/SA1388 family 4 249 8.3E-60 T 23-10-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 TON_1732 7a8795e8b839bebf305228d5e042d347 251 SUPERFAMILY SSF102705 2 246 1.7E-66 T 23-10-2018 IPR036069 GTP cyclohydrolase 1 type 2/Nif3 superfamily TON_1732 7a8795e8b839bebf305228d5e042d347 251 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 6 239 3.5E-57 T 23-10-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 TON_1754 1e3a9306925198d2d5089a3d41e58763 212 TIGRFAM TIGR00309 V_ATPase_subD: V-type ATPase, D subunit 6 209 7.5E-73 T 23-10-2018 IPR002699 ATPase, V1 complex, subunit D GO:0042626 Reactome: R-HSA-1222556|Reactome: R-HSA-6798695|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TON_1754 1e3a9306925198d2d5089a3d41e58763 212 Hamap MF_00271 V-type ATP synthase subunit D [atpD]. 4 211 26.016 T 23-10-2018 IPR002699 ATPase, V1 complex, subunit D GO:0042626 Reactome: R-HSA-1222556|Reactome: R-HSA-6798695|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TON_1754 1e3a9306925198d2d5089a3d41e58763 212 Pfam PF01813 ATP synthase subunit D 13 206 7.5E-63 T 23-10-2018 IPR002699 ATPase, V1 complex, subunit D GO:0042626 Reactome: R-HSA-1222556|Reactome: R-HSA-6798695|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TON_1185 bf1c19de56613479f32ce591ec8dade6 265 Pfam PF01917 Archaebacterial flagellin 4 251 2.2E-42 T 23-10-2018 IPR002774 Flagellin, archaea GO:0005198|GO:0006928 TON_1185 bf1c19de56613479f32ce591ec8dade6 265 TIGRFAM TIGR02537 arch_flag_Nterm: archaeal flagellin N-terminal-like domain 2 25 1.3E-5 T 23-10-2018 IPR013373 Flagellin/pilin, N-terminal TON_1252 7191f62e00fe1e766eb8ab925709cc64 172 Pfam PF09183 Domain of unknown function (DUF1947) 6 75 1.8E-5 T 23-10-2018 IPR015266 Domain of unknown function DUF1947 TON_1252 7191f62e00fe1e766eb8ab925709cc64 172 Gene3D G3DSA:3.10.450.120 1 78 1.3E-34 T 23-10-2018 TON_1252 7191f62e00fe1e766eb8ab925709cc64 172 Pfam PF01472 PUA domain 89 161 2.6E-24 T 23-10-2018 IPR002478 PUA domain GO:0003723 TON_1252 7191f62e00fe1e766eb8ab925709cc64 172 SMART SM00359 88 163 9.1E-25 T 23-10-2018 IPR002478 PUA domain GO:0003723 TON_1252 7191f62e00fe1e766eb8ab925709cc64 172 Gene3D G3DSA:2.30.130.10 79 171 2.1E-35 T 23-10-2018 IPR036974 PUA domain superfamily GO:0003723 TON_1252 7191f62e00fe1e766eb8ab925709cc64 172 PIRSF PIRSF005067 1 172 3.0E-45 T 23-10-2018 IPR016437 MCT-1/Tma20 TON_1252 7191f62e00fe1e766eb8ab925709cc64 172 TIGRFAM TIGR00451 unchar_dom_2: uncharacterized domain 2 52 164 1.4E-31 T 23-10-2018 IPR004521 Uncharacterised domain CHP00451 GO:0003723 TON_1252 7191f62e00fe1e766eb8ab925709cc64 172 SUPERFAMILY SSF88697 87 169 2.38E-24 T 23-10-2018 IPR015947 PUA-like superfamily TON_1252 7191f62e00fe1e766eb8ab925709cc64 172 TIGRFAM TIGR03684 arCOG00985: arCOG04150 universal archaeal PUA-domain protein 6 169 4.4E-55 T 23-10-2018 IPR022430 Conserved hypothetical protein CHP03684 TON_0262 e4e5e5a9e26aab2b7a68d11a3e90c6e8 248 Gene3D G3DSA:3.40.50.300 1 230 2.3E-68 T 23-10-2018 TON_0262 e4e5e5a9e26aab2b7a68d11a3e90c6e8 248 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 17 236 7.0E-59 T 23-10-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 TON_0262 e4e5e5a9e26aab2b7a68d11a3e90c6e8 248 Hamap MF_02040 Iron-sulfur cluster carrier protein. 13 242 28.533 T 23-10-2018 IPR019591 Mrp/NBP35 ATP-binding protein TON_0262 e4e5e5a9e26aab2b7a68d11a3e90c6e8 248 SUPERFAMILY SSF52540 19 243 1.92E-42 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_1274 78de3923ef4c6e65e5dcdfe147141310 114 Gene3D G3DSA:3.60.10.10 2 114 1.9E-10 T 23-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily TON_1274 78de3923ef4c6e65e5dcdfe147141310 114 SUPERFAMILY SSF56219 15 112 3.17E-11 T 23-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily TON_0077 7b6f0fb257e5df2ba54d88e55812f7be 121 SUPERFAMILY SSF50104 6 116 2.32E-38 T 23-10-2018 IPR008991 Translation protein SH3-like domain superfamily TON_0077 7b6f0fb257e5df2ba54d88e55812f7be 121 ProSitePatterns PS01108 Ribosomal protein L24 signature. 49 66 - T 23-10-2018 IPR005825 Ribosomal protein L24/L26, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 TON_0077 7b6f0fb257e5df2ba54d88e55812f7be 121 TIGRFAM TIGR01080 rplX_A_E: ribosomal protein uL24 6 120 5.3E-58 T 23-10-2018 IPR005756 Ribosomal protein L26/L24, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0077 7b6f0fb257e5df2ba54d88e55812f7be 121 Pfam PF00467 KOW motif 48 79 3.2E-10 T 23-10-2018 IPR005824 KOW TON_0077 7b6f0fb257e5df2ba54d88e55812f7be 121 Hamap MF_01326_A 50S ribosomal protein L24 [rplX]. 5 118 32.047 T 23-10-2018 IPR005756 Ribosomal protein L26/L24, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0077 7b6f0fb257e5df2ba54d88e55812f7be 121 Pfam PF16906 Ribosomal proteins L26 eukaryotic, L24P archaeal 5 119 2.1E-37 T 23-10-2018 IPR005756 Ribosomal protein L26/L24, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0077 7b6f0fb257e5df2ba54d88e55812f7be 121 Gene3D G3DSA:2.30.30.30 2 121 1.4E-53 T 23-10-2018 IPR014722 Ribosomal protein L2, domain 2 TON_0077 7b6f0fb257e5df2ba54d88e55812f7be 121 SMART SM00739 45 72 3.6E-7 T 23-10-2018 IPR005824 KOW TON_1831 8b7d9d4f2bf4fc1f994078513cfa7e01 306 Gene3D G3DSA:1.10.8.300 193 301 5.7E-31 T 23-10-2018 TON_1831 8b7d9d4f2bf4fc1f994078513cfa7e01 306 SUPERFAMILY SSF52540 3 276 5.94E-49 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_1831 8b7d9d4f2bf4fc1f994078513cfa7e01 306 SMART SM00382 30 172 2.0E-4 T 23-10-2018 IPR003593 AAA+ ATPase domain TON_1831 8b7d9d4f2bf4fc1f994078513cfa7e01 306 PIRSF PIRSF002849 1 306 4.4E-124 T 23-10-2018 TON_1831 8b7d9d4f2bf4fc1f994078513cfa7e01 306 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 33 163 5.4E-61 T 23-10-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 TON_1831 8b7d9d4f2bf4fc1f994078513cfa7e01 306 Gene3D G3DSA:3.40.50.300 14 180 2.4E-47 T 23-10-2018 TON_1386 c8ad88ad5bf770aa629064e138791706 375 SUPERFAMILY SSF103473 2 360 6.28E-72 T 23-10-2018 IPR036259 MFS transporter superfamily TON_1386 c8ad88ad5bf770aa629064e138791706 375 Pfam PF07690 Major Facilitator Superfamily 11 330 8.6E-45 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TON_1386 c8ad88ad5bf770aa629064e138791706 375 Gene3D G3DSA:1.20.1250.20 1 188 1.2E-42 T 23-10-2018 TON_1386 c8ad88ad5bf770aa629064e138791706 375 Gene3D G3DSA:1.20.1250.20 192 371 2.4E-27 T 23-10-2018 TON_0903 0a7f81f4fde92884b98f969b7971f098 281 Gene3D G3DSA:3.20.20.70 3 279 2.4E-82 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TON_0903 0a7f81f4fde92884b98f969b7971f098 281 PIRSF PIRSF038992 4 280 8.4E-90 T 23-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 TON_0903 0a7f81f4fde92884b98f969b7971f098 281 SUPERFAMILY SSF51569 8 266 6.59E-69 T 23-10-2018 TON_0903 0a7f81f4fde92884b98f969b7971f098 281 Pfam PF01791 DeoC/LacD family aldolase 24 251 1.8E-34 T 23-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 TON_0903 0a7f81f4fde92884b98f969b7971f098 281 SMART SM01133 23 251 1.4E-42 T 23-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 TON_0101 dd1e78cbd89e8f0de0d7f1d07f11fd62 209 Pfam PF05175 Methyltransferase small domain 42 205 4.7E-44 T 23-10-2018 IPR007848 Methyltransferase small domain GO:0008168 TON_0101 dd1e78cbd89e8f0de0d7f1d07f11fd62 209 Gene3D G3DSA:3.40.50.150 19 207 5.7E-50 T 23-10-2018 TON_0101 dd1e78cbd89e8f0de0d7f1d07f11fd62 209 SUPERFAMILY SSF53335 20 204 2.76E-41 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TON_0570 492f0f86714a6b4d55aecde557aa9085 331 PIRSF PIRSF001123 1 331 8.7E-88 T 23-10-2018 IPR008007 Peptidase M42 TON_0570 492f0f86714a6b4d55aecde557aa9085 331 Pfam PF05343 M42 glutamyl aminopeptidase 42 323 9.9E-87 T 23-10-2018 IPR008007 Peptidase M42 TON_0570 492f0f86714a6b4d55aecde557aa9085 331 SUPERFAMILY SSF101821 65 172 1.48E-22 T 23-10-2018 TON_0570 492f0f86714a6b4d55aecde557aa9085 331 SUPERFAMILY SSF53187 2 330 1.08E-54 T 23-10-2018 TON_0570 492f0f86714a6b4d55aecde557aa9085 331 Gene3D G3DSA:2.40.30.40 64 155 1.2E-115 T 23-10-2018 IPR023367 Peptidase M42, domain 2 TON_0570 492f0f86714a6b4d55aecde557aa9085 331 Gene3D G3DSA:3.40.630.10 8 324 1.2E-115 T 23-10-2018 TON_0791 f91f1e13b2b4dfe463037500073f120a 285 PIRSF PIRSF016175 7 284 1.2E-118 T 23-10-2018 IPR016648 Uncharacterised conserved protein UCP016175, prenyltransferase beta-subunit-related TON_0791 f91f1e13b2b4dfe463037500073f120a 285 SUPERFAMILY SSF48239 15 236 4.95E-18 T 23-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid TON_0791 f91f1e13b2b4dfe463037500073f120a 285 SUPERFAMILY SSF48239 215 278 3.45E-7 T 23-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid TON_0791 f91f1e13b2b4dfe463037500073f120a 285 Pfam PF00432 Prenyltransferase and squalene oxidase repeat 244 263 0.45 T 23-10-2018 IPR001330 PFTB repeat GO:0003824 TON_0791 f91f1e13b2b4dfe463037500073f120a 285 Pfam PF00432 Prenyltransferase and squalene oxidase repeat 12 32 3.5 T 23-10-2018 IPR001330 PFTB repeat GO:0003824 TON_0153 2185790cb8066971856ed7d9ea61381f 565 SUPERFAMILY SSF88688 416 531 1.6E-31 T 23-10-2018 IPR028995 Glycoside hydrolase families 57/38, central domain superfamily TON_0153 2185790cb8066971856ed7d9ea61381f 565 Pfam PF09210 Domain of unknown function (DUF1957) 429 527 4.9E-27 T 23-10-2018 IPR015293 Domain of unknown function DUF1957 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900 TON_0153 2185790cb8066971856ed7d9ea61381f 565 Pfam PF03065 Glycosyl hydrolase family 57 6 365 5.3E-73 T 23-10-2018 IPR004300 Glycoside hydrolase family 57, N-terminal domain GO:0003824|GO:0005975 TON_0153 2185790cb8066971856ed7d9ea61381f 565 Gene3D G3DSA:1.20.1430.10 417 562 5.5E-55 T 23-10-2018 IPR037090 Glycoside hydrolase families 57, central domain KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900 TON_0153 2185790cb8066971856ed7d9ea61381f 565 SUPERFAMILY SSF88713 2 416 7.79E-119 T 23-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 TON_0153 2185790cb8066971856ed7d9ea61381f 565 Gene3D G3DSA:3.20.110.10 1 416 3.6E-175 T 23-10-2018 IPR027291 Glycoside hydrolase 38, N-terminal domain superfamily TON_1722 e5f6e45c7c2848039e913c161ff6f36e 437 Hamap MF_00125 ATP phosphoribosyltransferase regulatory subunit [hisZ]. 17 386 25.899 T 23-10-2018 IPR004517 ATP phosphoribosyltransferase regulatory subunit GO:0000105|GO:0005737 TON_1722 e5f6e45c7c2848039e913c161ff6f36e 437 Pfam PF13393 Histidyl-tRNA synthetase 10 324 7.9E-67 T 23-10-2018 TON_1722 e5f6e45c7c2848039e913c161ff6f36e 437 SUPERFAMILY SSF52954 341 435 4.83E-24 T 23-10-2018 TON_1722 e5f6e45c7c2848039e913c161ff6f36e 437 Gene3D G3DSA:3.30.930.10 1 329 4.9E-110 T 23-10-2018 TON_1722 e5f6e45c7c2848039e913c161ff6f36e 437 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 7 423 2.1E-129 T 23-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 TON_1722 e5f6e45c7c2848039e913c161ff6f36e 437 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 3 433 31.517 T 23-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 TON_1722 e5f6e45c7c2848039e913c161ff6f36e 437 Gene3D G3DSA:3.40.50.800 339 434 1.0E-26 T 23-10-2018 IPR036621 Anticodon-binding domain superfamily TON_1722 e5f6e45c7c2848039e913c161ff6f36e 437 PIRSF PIRSF001549 1 435 2.5E-142 T 23-10-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 TON_1722 e5f6e45c7c2848039e913c161ff6f36e 437 TIGRFAM TIGR00443 hisZ_biosyn_reg: ATP phosphoribosyltransferase, regulatory subunit 12 327 2.3E-85 T 23-10-2018 IPR004517 ATP phosphoribosyltransferase regulatory subunit GO:0000105|GO:0005737 TON_1722 e5f6e45c7c2848039e913c161ff6f36e 437 SUPERFAMILY SSF55681 7 329 1.67E-87 T 23-10-2018 TON_1722 e5f6e45c7c2848039e913c161ff6f36e 437 Pfam PF03129 Anticodon binding domain 342 432 5.4E-21 T 23-10-2018 IPR004154 Anticodon-binding TON_1249 ec7c0bf5c15ba0ee9b0c7b90fa9d4006 382 SUPERFAMILY SSF51735 1 378 5.75E-72 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TON_1249 ec7c0bf5c15ba0ee9b0c7b90fa9d4006 382 Pfam PF01658 Myo-inositol-1-phosphate synthase 212 317 9.9E-20 T 23-10-2018 IPR013021 Myo-inositol-1-phosphate synthase, GAPDH-like KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 TON_1249 ec7c0bf5c15ba0ee9b0c7b90fa9d4006 382 Gene3D G3DSA:3.40.50.720 3 354 8.2E-132 T 23-10-2018 TON_1249 ec7c0bf5c15ba0ee9b0c7b90fa9d4006 382 SUPERFAMILY SSF55347 211 316 3.79E-28 T 23-10-2018 TON_1249 ec7c0bf5c15ba0ee9b0c7b90fa9d4006 382 PIRSF PIRSF015578 1 379 1.3E-95 T 23-10-2018 IPR002587 Myo-inositol-1-phosphate synthase GO:0004512|GO:0006021|GO:0008654 KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 TON_1249 ec7c0bf5c15ba0ee9b0c7b90fa9d4006 382 Gene3D G3DSA:3.30.360.10 216 319 8.2E-132 T 23-10-2018 TON_1249 ec7c0bf5c15ba0ee9b0c7b90fa9d4006 382 Pfam PF07994 Myo-inositol-1-phosphate synthase 112 319 4.3E-8 T 23-10-2018 IPR002587 Myo-inositol-1-phosphate synthase GO:0004512|GO:0006021|GO:0008654 KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 TON_0499 3590cff438eb7c05c0b56629f77765e5 166 SUPERFAMILY SSF55021 106 164 4.3E-8 T 23-10-2018 TON_0499 3590cff438eb7c05c0b56629f77765e5 166 PIRSF PIRSF004897 1 166 2.0E-70 T 23-10-2018 IPR014424 Uncharacterised conserved protein UCP004897, ACT- type TON_1485 5026e87396160e6957b6763b582d26d6 244 Pfam PF09883 Uncharacterized protein conserved in archaea (DUF2110) 6 235 9.2E-73 T 23-10-2018 IPR016757 Uncharacterised conserved protein UCP019322 TON_1485 5026e87396160e6957b6763b582d26d6 244 PIRSF PIRSF019322 2 244 1.7E-89 T 23-10-2018 IPR016757 Uncharacterised conserved protein UCP019322 TON_1630 fc3804dcc4fd66a20b5969deb273b7cd 383 Pfam PF17125 N-terminal domain of 16S rRNA methyltransferase RsmF 8 78 1.7E-7 T 23-10-2018 IPR031341 Ribosomal RNA small subunit methyltransferase F, N-terminal Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 TON_1630 fc3804dcc4fd66a20b5969deb273b7cd 383 Pfam PF01189 16S rRNA methyltransferase RsmB/F 192 381 5.1E-58 T 23-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 TON_1630 fc3804dcc4fd66a20b5969deb273b7cd 383 SUPERFAMILY SSF53335 6 383 1.3E-57 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TON_1630 fc3804dcc4fd66a20b5969deb273b7cd 383 Gene3D G3DSA:3.30.70.3130 2 83 1.4E-12 T 23-10-2018 TON_1630 fc3804dcc4fd66a20b5969deb273b7cd 383 SMART SM00359 90 164 4.4E-19 T 23-10-2018 IPR002478 PUA domain GO:0003723 TON_1630 fc3804dcc4fd66a20b5969deb273b7cd 383 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 316 332 4.0E-26 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TON_1630 fc3804dcc4fd66a20b5969deb273b7cd 383 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 269 281 4.0E-26 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TON_1630 fc3804dcc4fd66a20b5969deb273b7cd 383 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 203 213 4.0E-26 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TON_1630 fc3804dcc4fd66a20b5969deb273b7cd 383 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 174 188 4.0E-26 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TON_1630 fc3804dcc4fd66a20b5969deb273b7cd 383 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 365 382 4.0E-26 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TON_1630 fc3804dcc4fd66a20b5969deb273b7cd 383 TIGRFAM TIGR00446 nop2p: NOL1/NOP2/sun family putative RNA methylase 168 382 3.7E-64 T 23-10-2018 IPR011023 Nop2p GO:0003723|GO:0006364|GO:0008757 Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 TON_1630 fc3804dcc4fd66a20b5969deb273b7cd 383 SUPERFAMILY SSF88697 89 160 1.1E-16 T 23-10-2018 IPR015947 PUA-like superfamily TON_1630 fc3804dcc4fd66a20b5969deb273b7cd 383 Gene3D G3DSA:2.30.130.70 84 163 3.6E-15 T 23-10-2018 TON_1630 fc3804dcc4fd66a20b5969deb273b7cd 383 Pfam PF01472 PUA domain 93 159 7.6E-16 T 23-10-2018 IPR002478 PUA domain GO:0003723 TON_1630 fc3804dcc4fd66a20b5969deb273b7cd 383 Gene3D G3DSA:3.40.50.150 189 383 3.6E-62 T 23-10-2018 TON_0258 4ee64036d507c411efe0f7576431d621 124 Gene3D G3DSA:3.30.420.130 1 105 1.1E-31 T 23-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily TON_0258 4ee64036d507c411efe0f7576431d621 124 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 14 103 2.4E-20 T 23-10-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis TON_0258 4ee64036d507c411efe0f7576431d621 124 SUPERFAMILY SSF53146 1 120 5.1E-31 T 23-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily TON_0685 5187683e9b1b2bb64b273f27c30d400e 371 SUPERFAMILY SSF51445 101 342 3.64E-45 T 23-10-2018 IPR017853 Glycoside hydrolase superfamily TON_0685 5187683e9b1b2bb64b273f27c30d400e 371 PRINTS PR01545 Thermotoga maritima hypothetical protein TM1410 signature 154 173 1.2E-62 T 23-10-2018 IPR016062 Hypothetical protein TM1410-related TON_0685 5187683e9b1b2bb64b273f27c30d400e 371 PRINTS PR01545 Thermotoga maritima hypothetical protein TM1410 signature 177 194 1.2E-62 T 23-10-2018 IPR016062 Hypothetical protein TM1410-related TON_0685 5187683e9b1b2bb64b273f27c30d400e 371 PRINTS PR01545 Thermotoga maritima hypothetical protein TM1410 signature 323 333 1.2E-62 T 23-10-2018 IPR016062 Hypothetical protein TM1410-related TON_0685 5187683e9b1b2bb64b273f27c30d400e 371 PRINTS PR01545 Thermotoga maritima hypothetical protein TM1410 signature 214 233 1.2E-62 T 23-10-2018 IPR016062 Hypothetical protein TM1410-related TON_0685 5187683e9b1b2bb64b273f27c30d400e 371 PRINTS PR01545 Thermotoga maritima hypothetical protein TM1410 signature 196 214 1.2E-62 T 23-10-2018 IPR016062 Hypothetical protein TM1410-related TON_0685 5187683e9b1b2bb64b273f27c30d400e 371 PRINTS PR01545 Thermotoga maritima hypothetical protein TM1410 signature 122 135 1.2E-62 T 23-10-2018 IPR016062 Hypothetical protein TM1410-related TON_0685 5187683e9b1b2bb64b273f27c30d400e 371 PRINTS PR01545 Thermotoga maritima hypothetical protein TM1410 signature 108 121 1.2E-62 T 23-10-2018 IPR016062 Hypothetical protein TM1410-related TON_0685 5187683e9b1b2bb64b273f27c30d400e 371 PRINTS PR01545 Thermotoga maritima hypothetical protein TM1410 signature 249 261 1.2E-62 T 23-10-2018 IPR016062 Hypothetical protein TM1410-related TON_0685 5187683e9b1b2bb64b273f27c30d400e 371 PRINTS PR01545 Thermotoga maritima hypothetical protein TM1410 signature 268 282 1.2E-62 T 23-10-2018 IPR016062 Hypothetical protein TM1410-related TON_0685 5187683e9b1b2bb64b273f27c30d400e 371 TIGRFAM TIGR01370 TIGR01370: extracellular protein 78 355 3.0E-109 T 23-10-2018 IPR016063 Extracellular protein TON_0685 5187683e9b1b2bb64b273f27c30d400e 371 Gene3D G3DSA:3.20.20.70 91 359 1.5E-100 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TON_0685 5187683e9b1b2bb64b273f27c30d400e 371 Pfam PF03537 Glycoside-hydrolase family GH114 107 335 7.0E-30 T 23-10-2018 IPR004352 Glycoside-hydrolase family GH114, TIM-barrel domain TON_0366 677e4ae341b1e45421828855a0c30bdb 184 Gene3D G3DSA:2.40.320.10 1 179 1.4E-57 T 23-10-2018 TON_0366 677e4ae341b1e45421828855a0c30bdb 184 TIGRFAM TIGR00318 cyaB: putative adenylyl cyclase CyaB 1 173 5.9E-44 T 23-10-2018 IPR008173 Adenylyl cyclase CyaB KEGG: 00230+4.6.1.1 TON_0366 677e4ae341b1e45421828855a0c30bdb 184 SUPERFAMILY SSF55154 2 172 9.65E-37 T 23-10-2018 IPR033469 CYTH-like domain superfamily Reactome: R-HSA-196819 TON_0366 677e4ae341b1e45421828855a0c30bdb 184 SMART SM01118 1 175 1.3E-25 T 23-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 TON_0366 677e4ae341b1e45421828855a0c30bdb 184 Pfam PF01928 CYTH domain 1 169 9.2E-35 T 23-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 TON_0366 677e4ae341b1e45421828855a0c30bdb 184 ProDom PD009560 CYCLASE ADENYLATE CYCLASE ADENYLYL CYAB LYASE CLASS CYAB-TYPE THERMOPHILIC MJ0240 1 132 1.0E-60 T 23-10-2018 TON_0821 0d38e8d1d6011502503df498efc83eb3 427 Pfam PF00464 Serine hydroxymethyltransferase 11 388 8.1E-78 T 23-10-2018 IPR039429 Serine hydroxymethyltransferase-like domain KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 TON_0821 0d38e8d1d6011502503df498efc83eb3 427 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 220 236 - T 23-10-2018 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 TON_0821 0d38e8d1d6011502503df498efc83eb3 427 PIRSF PIRSF000412 2 425 1.1E-143 T 23-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 TON_0821 0d38e8d1d6011502503df498efc83eb3 427 SUPERFAMILY SSF53383 5 421 1.48E-130 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TON_0821 0d38e8d1d6011502503df498efc83eb3 427 Gene3D G3DSA:3.90.1150.10 282 426 7.0E-52 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TON_0821 0d38e8d1d6011502503df498efc83eb3 427 Gene3D G3DSA:3.40.640.10 34 281 3.9E-83 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TON_0821 0d38e8d1d6011502503df498efc83eb3 427 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 5 416 42.499 T 23-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 TON_0966 9a851473d2ff46a824deaa88610d498a 170 Pfam PF01936 NYN domain 32 162 5.1E-18 T 23-10-2018 IPR021139 NYN domain, limkain-b1-type TON_0966 9a851473d2ff46a824deaa88610d498a 170 Gene3D G3DSA:3.40.50.1010 24 165 1.4E-9 T 23-10-2018 TON_0966 9a851473d2ff46a824deaa88610d498a 170 ProDom PD010896 FAMILY DUF88 ARCHAEBACTERIAL PROTEIN MJ0482 PH0073 PF2040 VNG1608C MA3857 PF2039 33 105 5.0E-29 T 23-10-2018 TON_0966 9a851473d2ff46a824deaa88610d498a 170 TIGRFAM TIGR00288 TIGR00288: TIGR00288 family protein 22 166 3.9E-63 T 23-10-2018 IPR002790 Conserved hypothetical protein CHP00288 TON_0289 705c4167341db2a6193611f369301bbc 399 Pfam PF00266 Aminotransferase class-V 18 386 1.8E-138 T 23-10-2018 IPR000192 Aminotransferase class V domain TON_0289 705c4167341db2a6193611f369301bbc 399 Gene3D G3DSA:3.90.1150.10 14 387 1.6E-146 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TON_0289 705c4167341db2a6193611f369301bbc 399 SUPERFAMILY SSF53383 5 395 9.87E-120 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TON_0289 705c4167341db2a6193611f369301bbc 399 PIRSF PIRSF005572 15 399 2.7E-50 T 23-10-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 TON_0289 705c4167341db2a6193611f369301bbc 399 Gene3D G3DSA:3.40.640.10 36 292 1.6E-146 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TON_0029 7abf4b15cdd7af861cf08016292b0b31 256 Hamap MF_00623 Exosome complex component Rrp4 [rrp4]. 7 232 40.193 T 23-10-2018 IPR023474 Exosome complex component Rrp4 GO:0000178|GO:0008143 TON_0029 7abf4b15cdd7af861cf08016292b0b31 256 Gene3D G3DSA:2.40.50.140 58 142 1.7E-21 T 23-10-2018 TON_0029 7abf4b15cdd7af861cf08016292b0b31 256 SMART SM00316 63 137 3.0E-7 T 23-10-2018 IPR022967 RNA-binding domain, S1 TON_0029 7abf4b15cdd7af861cf08016292b0b31 256 Pfam PF15985 KH domain 149 195 8.0E-9 T 23-10-2018 IPR004088 K Homology domain, type 1 GO:0003723 TON_0029 7abf4b15cdd7af861cf08016292b0b31 256 SUPERFAMILY SSF110324 3 58 5.23E-14 T 23-10-2018 TON_0029 7abf4b15cdd7af861cf08016292b0b31 256 Gene3D G3DSA:3.30.1370.10 149 234 5.1E-34 T 23-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 TON_0029 7abf4b15cdd7af861cf08016292b0b31 256 Gene3D G3DSA:2.40.50.100 1 57 1.9E-21 T 23-10-2018 TON_0029 7abf4b15cdd7af861cf08016292b0b31 256 SUPERFAMILY SSF50249 59 152 1.8E-18 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold TON_0029 7abf4b15cdd7af861cf08016292b0b31 256 SUPERFAMILY SSF54791 148 228 2.21E-18 T 23-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 TON_0029 7abf4b15cdd7af861cf08016292b0b31 256 Pfam PF14382 Exosome complex exonuclease RRP4 N-terminal region 11 46 2.1E-7 T 23-10-2018 IPR025721 Exosome complex component, N-terminal domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TON_0029 7abf4b15cdd7af861cf08016292b0b31 256 SMART SM00322 146 211 6.2E-9 T 23-10-2018 IPR004087 K Homology domain GO:0003676 TON_0261 070bda44dc35d6adf0eb9de3f20d3ea1 139 ProSitePatterns PS01249 Hydrogenases expression/synthesis hypA family signature. 34 76 - T 23-10-2018 IPR020538 Hydrogenase nickel incorporation protein HypA/HybF, conserved site TON_0261 070bda44dc35d6adf0eb9de3f20d3ea1 139 PIRSF PIRSF004761 1 137 8.8E-34 T 23-10-2018 IPR000688 Hydrogenase maturation factor HypA/HybF GO:0016151|GO:0051604 TON_0261 070bda44dc35d6adf0eb9de3f20d3ea1 139 Gene3D G3DSA:3.30.2320.50 2 130 2.2E-27 T 23-10-2018 TON_0261 070bda44dc35d6adf0eb9de3f20d3ea1 139 Pfam PF01155 Hydrogenase/urease nickel incorporation, metallochaperone, hypA 1 132 5.6E-27 T 23-10-2018 IPR000688 Hydrogenase maturation factor HypA/HybF GO:0016151|GO:0051604 TON_0261 070bda44dc35d6adf0eb9de3f20d3ea1 139 Gene3D G3DSA:2.20.28.10 69 123 2.2E-27 T 23-10-2018 TON_0261 070bda44dc35d6adf0eb9de3f20d3ea1 139 Hamap MF_00213 Hydrogenase maturation factor HypA [hypA]. 1 134 21.34 T 23-10-2018 IPR000688 Hydrogenase maturation factor HypA/HybF GO:0016151|GO:0051604 TON_1167 3da1ff3b1c04d9f56a1b1164d8afa0d0 179 PIRSF PIRSF016123 1 179 2.0E-88 T 23-10-2018 IPR002845 tRNA ribose 2'-O-methyltransferase, aTrm56 GO:0002128|GO:0005737|GO:0008175 TON_1167 3da1ff3b1c04d9f56a1b1164d8afa0d0 179 ProDom PD016584 UPF0106 MK0803 MM0086 METAL MA3241 UNCHARACTERIZED DOMAIN TA0931 APE2006 ST0333 54 177 4.0E-58 T 23-10-2018 IPR002845 tRNA ribose 2'-O-methyltransferase, aTrm56 GO:0002128|GO:0005737|GO:0008175 TON_1167 3da1ff3b1c04d9f56a1b1164d8afa0d0 179 Pfam PF01994 tRNA ribose 2'-O-methyltransferase, aTrm56 54 175 1.5E-53 T 23-10-2018 IPR002845 tRNA ribose 2'-O-methyltransferase, aTrm56 GO:0002128|GO:0005737|GO:0008175 TON_1167 3da1ff3b1c04d9f56a1b1164d8afa0d0 179 Gene3D G3DSA:3.40.1280.10 1 178 6.5E-81 T 23-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal TON_1167 3da1ff3b1c04d9f56a1b1164d8afa0d0 179 Hamap MF_00077 tRNA (cytidine(56)-2'-O)-methyltransferase. 1 177 44.801 T 23-10-2018 IPR002845 tRNA ribose 2'-O-methyltransferase, aTrm56 GO:0002128|GO:0005737|GO:0008175 TON_1167 3da1ff3b1c04d9f56a1b1164d8afa0d0 179 SUPERFAMILY SSF75217 1 175 5.23E-72 T 23-10-2018 IPR029028 Alpha/beta knot methyltransferases TON_0377 936d12bac6f1da7b7224629beb8cc9ec 195 Gene3D G3DSA:2.40.50.100 11 60 8.1E-17 T 23-10-2018 TON_0377 936d12bac6f1da7b7224629beb8cc9ec 195 SMART SM00316 68 148 8.3E-11 T 23-10-2018 IPR022967 RNA-binding domain, S1 TON_0377 936d12bac6f1da7b7224629beb8cc9ec 195 Gene3D G3DSA:2.20.70.10 155 188 1.0E-15 T 23-10-2018 TON_0377 936d12bac6f1da7b7224629beb8cc9ec 195 Gene3D G3DSA:2.40.50.140 66 154 5.8E-23 T 23-10-2018 TON_0377 936d12bac6f1da7b7224629beb8cc9ec 195 Pfam PF10447 Exosome component EXOSC1/CSL4 66 122 3.7E-5 T 23-10-2018 IPR019495 Exosome complex component CSL4, C-terminal GO:0000178|GO:0003723 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TON_0377 936d12bac6f1da7b7224629beb8cc9ec 195 Hamap MF_00975 Exosome complex component Csl4 [csl4]. 12 192 28.455 T 23-10-2018 IPR030850 Exosome complex component Csl4, archaea GO:0000178|GO:0006396 TON_0377 936d12bac6f1da7b7224629beb8cc9ec 195 Pfam PF14382 Exosome complex exonuclease RRP4 N-terminal region 12 48 4.9E-8 T 23-10-2018 IPR025721 Exosome complex component, N-terminal domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TON_0377 936d12bac6f1da7b7224629beb8cc9ec 195 SUPERFAMILY SSF50249 64 185 1.4E-29 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold TON_0377 936d12bac6f1da7b7224629beb8cc9ec 195 SUPERFAMILY SSF110324 11 63 8.37E-12 T 23-10-2018 TON_1678 a8f38db977db71510c3566c0338586e7 163 SUPERFAMILY SSF54534 2 150 1.67E-48 T 23-10-2018 TON_1678 a8f38db977db71510c3566c0338586e7 163 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 3 147 2.2E-20 T 23-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain TON_1678 a8f38db977db71510c3566c0338586e7 163 Gene3D G3DSA:3.10.50.80 2 158 1.9E-55 T 23-10-2018 TON_1096 6879360733f0dc73cb90a8e7cb2ed69e 235 SUPERFAMILY SSF56300 1 235 6.23E-64 T 23-10-2018 TON_1096 6879360733f0dc73cb90a8e7cb2ed69e 235 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 1 196 1.8E-30 T 23-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 TON_1096 6879360733f0dc73cb90a8e7cb2ed69e 235 Gene3D G3DSA:3.60.21.10 2 235 4.6E-70 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like TON_1096 6879360733f0dc73cb90a8e7cb2ed69e 235 TIGRFAM TIGR00040 yfcE: phosphodiesterase, MJ0936 family 1 197 1.9E-17 T 23-10-2018 IPR000979 Phosphodiesterase MJ0936/Vps29 Reactome: R-HSA-3238698 TON_1096 6879360733f0dc73cb90a8e7cb2ed69e 235 PIRSF PIRSF000883 1 235 2.5E-71 T 23-10-2018 IPR011152 Phosphoesterase MJ0912 TON_1334 025bd496b2558f27804256b6c1922430 134 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 10 132 41.81 T 23-10-2018 IPR002930 Glycine cleavage system H-protein GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 TON_1334 025bd496b2558f27804256b6c1922430 134 Pfam PF01597 Glycine cleavage H-protein 13 133 4.3E-51 T 23-10-2018 IPR033753 Glycine cleavage system H-protein/Simiate TON_1334 025bd496b2558f27804256b6c1922430 134 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 54 83 - T 23-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 TON_1334 025bd496b2558f27804256b6c1922430 134 SUPERFAMILY SSF51230 10 133 3.4E-43 T 23-10-2018 IPR011053 Single hybrid motif TON_1334 025bd496b2558f27804256b6c1922430 134 Gene3D G3DSA:2.40.50.100 2 132 2.0E-52 T 23-10-2018 TON_1334 025bd496b2558f27804256b6c1922430 134 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 11 132 3.5E-47 T 23-10-2018 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 TON_0129 e54a2c104ab7958f61cc13f878bf2cf9 445 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 326 424 1.6E-16 T 23-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 TON_0129 e54a2c104ab7958f61cc13f878bf2cf9 445 Gene3D G3DSA:3.50.50.60 107 423 8.4E-118 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TON_0129 e54a2c104ab7958f61cc13f878bf2cf9 445 SUPERFAMILY SSF51905 1 309 8.84E-50 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TON_0129 e54a2c104ab7958f61cc13f878bf2cf9 445 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 98 116 1.0E-27 T 23-10-2018 TON_0129 e54a2c104ab7958f61cc13f878bf2cf9 445 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 144 162 1.0E-27 T 23-10-2018 TON_0129 e54a2c104ab7958f61cc13f878bf2cf9 445 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 227 243 1.0E-27 T 23-10-2018 TON_0129 e54a2c104ab7958f61cc13f878bf2cf9 445 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 1.0E-27 T 23-10-2018 TON_0129 e54a2c104ab7958f61cc13f878bf2cf9 445 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 253 275 1.0E-27 T 23-10-2018 TON_0129 e54a2c104ab7958f61cc13f878bf2cf9 445 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 268 275 1.3E-21 T 23-10-2018 TON_0129 e54a2c104ab7958f61cc13f878bf2cf9 445 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 1.3E-21 T 23-10-2018 TON_0129 e54a2c104ab7958f61cc13f878bf2cf9 445 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 228 242 1.3E-21 T 23-10-2018 TON_0129 e54a2c104ab7958f61cc13f878bf2cf9 445 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 144 169 1.3E-21 T 23-10-2018 TON_0129 e54a2c104ab7958f61cc13f878bf2cf9 445 Gene3D G3DSA:3.50.50.60 5 333 8.4E-118 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TON_0129 e54a2c104ab7958f61cc13f878bf2cf9 445 SUPERFAMILY SSF55424 318 439 6.19E-26 T 23-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 TON_0129 e54a2c104ab7958f61cc13f878bf2cf9 445 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 297 3.1E-57 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TON_1236 a56a527f67a69624853f70763965293e 164 Gene3D G3DSA:3.60.21.10 1 164 2.4E-40 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like TON_1236 a56a527f67a69624853f70763965293e 164 SUPERFAMILY SSF56300 2 162 9.27E-38 T 23-10-2018 TON_1236 a56a527f67a69624853f70763965293e 164 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 2 152 4.7E-27 T 23-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 TON_1236 a56a527f67a69624853f70763965293e 164 TIGRFAM TIGR00040 yfcE: phosphodiesterase, MJ0936 family 2 158 3.5E-34 T 23-10-2018 IPR000979 Phosphodiesterase MJ0936/Vps29 Reactome: R-HSA-3238698 TON_0444 8c83b6f62184f9b63f7ecb14f771da77 618 SUPERFAMILY SSF48310 207 601 1.57E-102 T 23-10-2018 IPR036021 Aldehyde ferredoxin oxidoreductase-like, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 TON_0444 8c83b6f62184f9b63f7ecb14f771da77 618 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 217 597 1.8E-96 T 23-10-2018 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 TON_0444 8c83b6f62184f9b63f7ecb14f771da77 618 SMART SM00790 4 203 7.4E-112 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 TON_0444 8c83b6f62184f9b63f7ecb14f771da77 618 Gene3D G3DSA:1.10.599.10 235 597 1.4E-90 T 23-10-2018 IPR013985 Aldehyde ferredoxin oxidoreductase, domain 3 GO:0016625|GO:0051536|GO:0055114 KEGG: 00030+1.2.7.5 TON_0444 8c83b6f62184f9b63f7ecb14f771da77 618 Gene3D G3DSA:3.60.9.10 1 206 8.9E-75 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily TON_0444 8c83b6f62184f9b63f7ecb14f771da77 618 SUPERFAMILY SSF56228 1 203 4.19E-68 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily TON_0444 8c83b6f62184f9b63f7ecb14f771da77 618 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 7 200 2.3E-69 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 TON_0444 8c83b6f62184f9b63f7ecb14f771da77 618 Gene3D G3DSA:1.10.569.10 237 428 1.4E-90 T 23-10-2018 IPR013984 Aldehyde ferredoxin oxidoreductase, domain 2 TON_0423 d3a546ca3a52e724bf541209e30d8657 573 Gene3D G3DSA:1.10.3080.10 12 438 2.2E-96 T 23-10-2018 IPR014743 Chloride channel, core Reactome: R-HSA-2672351 TON_0423 d3a546ca3a52e724bf541209e30d8657 573 SMART SM00116 452 500 1.7E-6 T 23-10-2018 IPR000644 CBS domain TON_0423 d3a546ca3a52e724bf541209e30d8657 573 SMART SM00116 514 564 2.3 T 23-10-2018 IPR000644 CBS domain TON_0423 d3a546ca3a52e724bf541209e30d8657 573 Gene3D G3DSA:3.10.580.10 500 564 1.1E-7 T 23-10-2018 TON_0423 d3a546ca3a52e724bf541209e30d8657 573 Pfam PF00571 CBS domain 445 497 4.3E-11 T 23-10-2018 IPR000644 CBS domain TON_0423 d3a546ca3a52e724bf541209e30d8657 573 Pfam PF00571 CBS domain 507 562 1.1E-6 T 23-10-2018 IPR000644 CBS domain TON_0423 d3a546ca3a52e724bf541209e30d8657 573 PRINTS PR00762 Chloride channel signature 82 99 1.8E-19 T 23-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 TON_0423 d3a546ca3a52e724bf541209e30d8657 573 PRINTS PR00762 Chloride channel signature 162 181 1.8E-19 T 23-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 TON_0423 d3a546ca3a52e724bf541209e30d8657 573 PRINTS PR00762 Chloride channel signature 327 347 1.8E-19 T 23-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 TON_0423 d3a546ca3a52e724bf541209e30d8657 573 PRINTS PR00762 Chloride channel signature 380 399 1.8E-19 T 23-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 TON_0423 d3a546ca3a52e724bf541209e30d8657 573 PRINTS PR00762 Chloride channel signature 362 378 1.8E-19 T 23-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 TON_0423 d3a546ca3a52e724bf541209e30d8657 573 SUPERFAMILY SSF81340 6 432 4.45E-98 T 23-10-2018 IPR014743 Chloride channel, core Reactome: R-HSA-2672351 TON_0423 d3a546ca3a52e724bf541209e30d8657 573 SUPERFAMILY SSF54631 440 565 4.45E-24 T 23-10-2018 TON_0423 d3a546ca3a52e724bf541209e30d8657 573 Pfam PF00654 Voltage gated chloride channel 70 412 3.5E-84 T 23-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 TON_0423 d3a546ca3a52e724bf541209e30d8657 573 Gene3D G3DSA:3.10.580.10 439 499 6.1E-13 T 23-10-2018 TON_1907 d47ddb75fee4066754065b64448ae11f 426 Gene3D G3DSA:3.40.50.200 107 426 4.4E-108 T 23-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 TON_1907 d47ddb75fee4066754065b64448ae11f 426 SUPERFAMILY SSF54897 44 93 6.97E-7 T 23-10-2018 TON_1907 d47ddb75fee4066754065b64448ae11f 426 Pfam PF00082 Subtilase family 138 413 1.4E-45 T 23-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 TON_1907 d47ddb75fee4066754065b64448ae11f 426 Gene3D G3DSA:3.30.70.80 27 94 4.9E-23 T 23-10-2018 IPR037045 Peptidase S8 propeptide/proteinase inhibitor I9 superfamily Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 TON_1907 d47ddb75fee4066754065b64448ae11f 426 PRINTS PR00723 Subtilisin serine protease family (S8) signature 349 365 6.9E-19 T 23-10-2018 IPR015500 Peptidase S8, subtilisin-related TON_1907 d47ddb75fee4066754065b64448ae11f 426 PRINTS PR00723 Subtilisin serine protease family (S8) signature 134 153 6.9E-19 T 23-10-2018 IPR015500 Peptidase S8, subtilisin-related TON_1907 d47ddb75fee4066754065b64448ae11f 426 PRINTS PR00723 Subtilisin serine protease family (S8) signature 177 190 6.9E-19 T 23-10-2018 IPR015500 Peptidase S8, subtilisin-related TON_1907 d47ddb75fee4066754065b64448ae11f 426 SUPERFAMILY SSF52743 110 424 1.28E-83 T 23-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 TON_1907 d47ddb75fee4066754065b64448ae11f 426 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 350 360 - T 23-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site TON_0063 4185859bd99acd48152f92de82ded10b 182 Gene3D G3DSA:3.90.1170.10 1 180 6.1E-65 T 23-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 TON_0063 4185859bd99acd48152f92de82ded10b 182 Hamap MF_00448 50S ribosomal protein L10e [rpl10e]. 1 174 37.793 T 23-10-2018 IPR022981 Ribosomal protein L10e, archaea TON_0063 4185859bd99acd48152f92de82ded10b 182 ProSitePatterns PS01257 Ribosomal protein L10e signature. 105 126 - T 23-10-2018 IPR018255 Ribosomal protein L10e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0063 4185859bd99acd48152f92de82ded10b 182 Pfam PF00252 Ribosomal protein L16p/L10e 14 159 4.9E-34 T 23-10-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 TON_0063 4185859bd99acd48152f92de82ded10b 182 PIRSF PIRSF005590 1 180 1.7E-70 T 23-10-2018 IPR001197 Ribosomal protein L10e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0063 4185859bd99acd48152f92de82ded10b 182 SUPERFAMILY SSF54686 4 168 1.01E-56 T 23-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 TON_1464 89db13fb0dac0182f6b85d1672ea2d9e 215 Gene3D G3DSA:1.20.58.220 3 212 5.3E-48 T 23-10-2018 IPR038078 PhoU-like domain superfamily TON_1464 89db13fb0dac0182f6b85d1672ea2d9e 215 Pfam PF01865 Protein of unknown function DUF47 7 211 5.8E-40 T 23-10-2018 IPR018445 Putative phosphate transport regulator TON_1464 89db13fb0dac0182f6b85d1672ea2d9e 215 TIGRFAM TIGR00153 TIGR00153: TIGR00153 family protein 16 214 1.4E-38 T 23-10-2018 IPR002727 Protein of unknown function DUF47 TON_1464 89db13fb0dac0182f6b85d1672ea2d9e 215 SUPERFAMILY SSF109755 29 208 1.7E-7 T 23-10-2018 TON_0937 a97f18006ce4ada284e81954e8040dfa 925 Pfam PF08494 DEAD/H associated 583 750 1.7E-17 T 23-10-2018 IPR013701 DEAD/H associated GO:0005524|GO:0016818 TON_0937 a97f18006ce4ada284e81954e8040dfa 925 Gene3D G3DSA:3.40.50.300 216 368 7.6E-31 T 23-10-2018 TON_0937 a97f18006ce4ada284e81954e8040dfa 925 SMART SM00490 259 341 5.2E-25 T 23-10-2018 IPR001650 Helicase, C-terminal TON_0937 a97f18006ce4ada284e81954e8040dfa 925 Pfam PF00270 DEAD/DEAH box helicase 18 182 7.1E-28 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 TON_0937 a97f18006ce4ada284e81954e8040dfa 925 Pfam PF00271 Helicase conserved C-terminal domain 237 336 8.6E-20 T 23-10-2018 IPR001650 Helicase, C-terminal TON_0937 a97f18006ce4ada284e81954e8040dfa 925 SMART SM00487 12 216 4.3E-36 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TON_0937 a97f18006ce4ada284e81954e8040dfa 925 PIRSF PIRSF037307 1 913 0.0 T 23-10-2018 IPR017170 Lhr-like ATP-dependent RNA helicase, predicted GO:0005524|GO:0016818 TON_0937 a97f18006ce4ada284e81954e8040dfa 925 SUPERFAMILY SSF52540 28 350 9.07E-53 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_0937 a97f18006ce4ada284e81954e8040dfa 925 Gene3D G3DSA:3.40.50.300 2 202 1.3E-45 T 23-10-2018 TON_0498 f2496161133d5c58b69f512a1bc7be93 168 Pfam PF01899 Na+/H+ ion antiporter subunit 15 164 3.0E-49 T 23-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 TON_0498 f2496161133d5c58b69f512a1bc7be93 168 PIRSF PIRSF019239 4 168 7.0E-56 T 23-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 TON_1015 1ea666df32f364347aa6cb9a422daa85 240 Gene3D G3DSA:2.40.50.580 2 80 4.9E-25 T 23-10-2018 TON_1015 1ea666df32f364347aa6cb9a422daa85 240 Pfam PF03749 Sugar fermentation stimulation protein 16 223 1.9E-48 T 23-10-2018 IPR005224 Sugar fermentation stimulation protein TON_1015 1ea666df32f364347aa6cb9a422daa85 240 Gene3D G3DSA:3.40.1350.60 81 235 1.5E-41 T 23-10-2018 TON_1015 1ea666df32f364347aa6cb9a422daa85 240 TIGRFAM TIGR00230 sfsA: sugar fermentation stimulation protein 9 233 5.5E-53 T 23-10-2018 IPR005224 Sugar fermentation stimulation protein TON_1015 1ea666df32f364347aa6cb9a422daa85 240 Hamap MF_00095 Sugar fermentation stimulation protein A [sfsA]. 5 235 38.382 T 23-10-2018 IPR005224 Sugar fermentation stimulation protein TON_1503 4575449cf5b921e301c0101908e8c415 280 SUPERFAMILY SSF52096 15 241 1.06E-29 T 23-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TON_1503 4575449cf5b921e301c0101908e8c415 280 Gene3D G3DSA:3.90.226.10 63 270 1.7E-23 T 23-10-2018 TON_1503 4575449cf5b921e301c0101908e8c415 280 Pfam PF01972 Serine dehydrogenase proteinase 6 276 1.7E-150 T 23-10-2018 IPR002825 Peptidase S49, serine-peptidase prokaryotes GO:0016021 TON_1939 2ebb7e9a383be0fe7e2c75f33b171866 360 Pfam PF00924 Mechanosensitive ion channel 140 339 1.0E-60 T 23-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 TON_1939 2ebb7e9a383be0fe7e2c75f33b171866 360 Gene3D G3DSA:2.30.30.60 200 249 9.4E-14 T 23-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily TON_1939 2ebb7e9a383be0fe7e2c75f33b171866 360 Gene3D G3DSA:3.30.70.100 251 343 3.3E-28 T 23-10-2018 TON_1939 2ebb7e9a383be0fe7e2c75f33b171866 360 SUPERFAMILY SSF82861 101 183 1.83E-6 T 23-10-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 TON_1939 2ebb7e9a383be0fe7e2c75f33b171866 360 ProSitePatterns PS01246 Uncharacterized protein family UPF0003 signature. 214 248 - T 23-10-2018 IPR006686 Mechanosensitive ion channel MscS, conserved site GO:0016020 TON_1939 2ebb7e9a383be0fe7e2c75f33b171866 360 SUPERFAMILY SSF50182 185 249 4.25E-18 T 23-10-2018 IPR010920 LSM domain superfamily TON_1939 2ebb7e9a383be0fe7e2c75f33b171866 360 SUPERFAMILY SSF82689 252 350 1.83E-31 T 23-10-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 TON_1373 6c9d2b0b26078939b64b7022fcfc0d4b 243 PIRSF PIRSF037724 1 237 4.7E-105 T 23-10-2018 IPR017271 Transcription regulator HTH, MJ1545, predicted TON_1373 6c9d2b0b26078939b64b7022fcfc0d4b 243 SUPERFAMILY SSF47413 22 75 4.1E-12 T 23-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TON_1373 6c9d2b0b26078939b64b7022fcfc0d4b 243 SMART SM00530 26 81 1.1E-12 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TON_1373 6c9d2b0b26078939b64b7022fcfc0d4b 243 Gene3D G3DSA:1.10.260.40 24 80 7.9E-11 T 23-10-2018 TON_1373 6c9d2b0b26078939b64b7022fcfc0d4b 243 Pfam PF01381 Helix-turn-helix 28 75 4.0E-9 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TON_1823 b240f1dfddb3e8d3208acde522631a06 363 Pfam PF00534 Glycosyl transferases group 1 192 348 8.9E-35 T 23-10-2018 IPR001296 Glycosyl transferase, family 1 TON_1823 b240f1dfddb3e8d3208acde522631a06 363 Gene3D G3DSA:3.40.50.2000 3 183 3.2E-21 T 23-10-2018 TON_1823 b240f1dfddb3e8d3208acde522631a06 363 Pfam PF13439 Glycosyltransferase Family 4 20 169 1.0E-13 T 23-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 TON_1823 b240f1dfddb3e8d3208acde522631a06 363 SUPERFAMILY SSF53756 8 355 8.64E-64 T 23-10-2018 TON_1823 b240f1dfddb3e8d3208acde522631a06 363 Gene3D G3DSA:3.40.50.2000 189 358 1.8E-40 T 23-10-2018 TON_1966 a041914a805dee7ac798d73a9633db7a 450 SUPERFAMILY SSF48013 9 163 9.55E-24 T 23-10-2018 IPR035926 NusB-like superfamily TON_1966 a041914a805dee7ac798d73a9633db7a 450 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 237 251 2.3E-21 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TON_1966 a041914a805dee7ac798d73a9633db7a 450 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 381 397 2.3E-21 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TON_1966 a041914a805dee7ac798d73a9633db7a 450 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 266 276 2.3E-21 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TON_1966 a041914a805dee7ac798d73a9633db7a 450 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 433 450 2.3E-21 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TON_1966 a041914a805dee7ac798d73a9633db7a 450 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 331 343 2.3E-21 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TON_1966 a041914a805dee7ac798d73a9633db7a 450 Gene3D G3DSA:3.40.50.150 154 450 6.6E-79 T 23-10-2018 TON_1966 a041914a805dee7ac798d73a9633db7a 450 Gene3D G3DSA:1.10.940.10 6 140 6.0E-14 T 23-10-2018 IPR035926 NusB-like superfamily TON_1966 a041914a805dee7ac798d73a9633db7a 450 SUPERFAMILY SSF53335 148 450 1.94E-71 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TON_1966 a041914a805dee7ac798d73a9633db7a 450 Pfam PF01189 16S rRNA methyltransferase RsmB/F 255 449 1.4E-49 T 23-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 TON_1966 a041914a805dee7ac798d73a9633db7a 450 Pfam PF01029 NusB family 10 133 1.3E-18 T 23-10-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 TON_0700 5bb62586c9feaec090fa1b1a65e4b8a1 390 Pfam PF13173 AAA domain 42 157 5.1E-21 T 23-10-2018 TON_0700 5bb62586c9feaec090fa1b1a65e4b8a1 390 SUPERFAMILY SSF52540 41 162 3.62E-13 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_1713 36023d5fffba0550698cf7d6e167bfd3 232 Pfam PF13419 Haloacid dehalogenase-like hydrolase 3 195 4.7E-21 T 23-10-2018 TON_1713 36023d5fffba0550698cf7d6e167bfd3 232 Gene3D G3DSA:3.40.50.1000 3 217 1.6E-39 T 23-10-2018 IPR023214 HAD superfamily TON_1713 36023d5fffba0550698cf7d6e167bfd3 232 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 91 189 2.0E-12 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TON_1713 36023d5fffba0550698cf7d6e167bfd3 232 SUPERFAMILY SSF56784 3 223 2.4E-37 T 23-10-2018 IPR036412 HAD-like superfamily TON_1713 36023d5fffba0550698cf7d6e167bfd3 232 Gene3D G3DSA:1.10.150.520 14 96 1.6E-39 T 23-10-2018 TON_1469 4c8e204cfe84d131e79970d108dedde1 159 SMART SM00116 107 155 1.1E-6 T 23-10-2018 IPR000644 CBS domain TON_1469 4c8e204cfe84d131e79970d108dedde1 159 SMART SM00116 30 76 4.5 T 23-10-2018 IPR000644 CBS domain TON_1469 4c8e204cfe84d131e79970d108dedde1 159 Pfam PF00571 CBS domain 100 154 2.5E-10 T 23-10-2018 IPR000644 CBS domain TON_1469 4c8e204cfe84d131e79970d108dedde1 159 Pfam PF00571 CBS domain 26 74 6.1E-9 T 23-10-2018 IPR000644 CBS domain TON_1469 4c8e204cfe84d131e79970d108dedde1 159 Gene3D G3DSA:3.10.580.10 6 80 6.0E-9 T 23-10-2018 TON_1469 4c8e204cfe84d131e79970d108dedde1 159 SUPERFAMILY SSF54631 13 154 8.5E-25 T 23-10-2018 TON_1469 4c8e204cfe84d131e79970d108dedde1 159 Gene3D G3DSA:3.10.580.10 81 156 1.3E-13 T 23-10-2018 TON_1393 06b7057bac88cc71a43075363cb4a56b 304 Pfam PF01895 PhoU domain 138 230 4.5E-14 T 23-10-2018 IPR026022 PhoU domain TON_1393 06b7057bac88cc71a43075363cb4a56b 304 Gene3D G3DSA:1.20.58.220 134 236 3.4E-12 T 23-10-2018 IPR038078 PhoU-like domain superfamily TON_1393 06b7057bac88cc71a43075363cb4a56b 304 SMART SM00966 8 54 8.0E-9 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 TON_1393 06b7057bac88cc71a43075363cb4a56b 304 SUPERFAMILY SSF109755 125 301 1.83E-17 T 23-10-2018 TON_1393 06b7057bac88cc71a43075363cb4a56b 304 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 8 51 1.3E-7 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 TON_1431 6fe701bba00fea9dd50365a74d784889 151 Gene3D G3DSA:3.30.980.10 2 76 4.8E-32 T 23-10-2018 TON_1431 6fe701bba00fea9dd50365a74d784889 151 SUPERFAMILY SSF55186 4 148 1.01E-35 T 23-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 TON_1431 6fe701bba00fea9dd50365a74d784889 151 Gene3D G3DSA:3.30.54.20 77 119 3.0E-19 T 23-10-2018 TON_1555 ceb5c4f928478500ca70367013884955 188 SUPERFAMILY SSF51306 29 120 5.23E-10 T 23-10-2018 IPR036286 LexA/Signal peptidase-like superfamily TON_1555 ceb5c4f928478500ca70367013884955 188 Pfam PF00717 Peptidase S24-like 37 84 1.3E-5 T 23-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C TON_1555 ceb5c4f928478500ca70367013884955 188 TIGRFAM TIGR02228 sigpep_I_arch: signal peptidase I 7 130 1.4E-20 T 23-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 TON_1385 b59ed03c74cca4a00be7fd2117ea22f9 398 SMART SM00382 172 311 3.0E-24 T 23-10-2018 IPR003593 AAA+ ATPase domain TON_1385 b59ed03c74cca4a00be7fd2117ea22f9 398 SUPERFAMILY SSF52540 135 388 1.07E-71 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_1385 b59ed03c74cca4a00be7fd2117ea22f9 398 Gene3D G3DSA:3.40.50.300 129 309 3.0E-71 T 23-10-2018 TON_1385 b59ed03c74cca4a00be7fd2117ea22f9 398 TIGRFAM TIGR01242 26Sp45: 26S proteasome subunit P45 family 19 380 6.2E-198 T 23-10-2018 IPR005937 26S proteasome regulatory subunit P45-like GO:0005737|GO:0016787|GO:0030163 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 TON_1385 b59ed03c74cca4a00be7fd2117ea22f9 398 Gene3D G3DSA:2.40.50.140 24 128 2.3E-26 T 23-10-2018 TON_1385 b59ed03c74cca4a00be7fd2117ea22f9 398 Gene3D G3DSA:1.10.8.60 310 381 2.0E-28 T 23-10-2018 TON_1385 b59ed03c74cca4a00be7fd2117ea22f9 398 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 176 309 1.9E-43 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TON_1385 b59ed03c74cca4a00be7fd2117ea22f9 398 Hamap MF_00553 Proteasome-activating nucleotidase [pan]. 2 397 47.095 T 23-10-2018 IPR023501 Proteasome-activating nucleotidase PAN TON_1385 b59ed03c74cca4a00be7fd2117ea22f9 398 ProSitePatterns PS00674 AAA-protein family signature. 279 297 - T 23-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 TON_1385 b59ed03c74cca4a00be7fd2117ea22f9 398 Pfam PF16450 Proteasomal ATPase OB/ID domain 65 122 6.2E-7 T 23-10-2018 IPR032501 Proteasomal ATPase, OB/ID domain TON_1601 a660410eed9619d2f7d0fe89fd0fca98 175 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 1 169 1.3E-13 T 23-10-2018 IPR007404 LexA-binding, inner membrane-associated putative hydrolase TON_0472 630767041ffb9c72261a7438256fffb8 116 Pfam PF13192 Thioredoxin domain 33 106 2.1E-9 T 23-10-2018 IPR012336 Thioredoxin-like fold TON_0472 630767041ffb9c72261a7438256fffb8 116 Gene3D G3DSA:3.40.30.10 10 111 1.1E-15 T 23-10-2018 TON_0472 630767041ffb9c72261a7438256fffb8 116 SUPERFAMILY SSF52833 24 109 3.65E-15 T 23-10-2018 IPR036249 Thioredoxin-like superfamily TON_0446 21e71aa7d7c7977d8dbdfad836157eff 241 Pfam PF01588 Putative tRNA binding domain 138 224 8.7E-19 T 23-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 TON_0446 21e71aa7d7c7977d8dbdfad836157eff 241 Gene3D G3DSA:2.40.50.140 125 241 6.1E-36 T 23-10-2018 TON_0446 21e71aa7d7c7977d8dbdfad836157eff 241 Gene3D G3DSA:1.20.1440.150 1 124 8.2E-61 T 23-10-2018 TON_0446 21e71aa7d7c7977d8dbdfad836157eff 241 SUPERFAMILY SSF50249 134 223 6.61E-17 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold TON_0931 c82ab1efe6d81389bbb2e194e7f41d33 209 SMART SM00418 15 97 0.0021 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TON_0931 c82ab1efe6d81389bbb2e194e7f41d33 209 Gene3D G3DSA:1.10.10.10 9 91 1.7E-15 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TON_0931 c82ab1efe6d81389bbb2e194e7f41d33 209 Pfam PF12840 Helix-turn-helix domain 15 70 1.3E-11 T 23-10-2018 TON_0931 c82ab1efe6d81389bbb2e194e7f41d33 209 SUPERFAMILY SSF46785 7 95 4.55E-17 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TON_0910 5e40dad2130cd36895b34b1bfce53ad5 263 SUPERFAMILY SSF53474 7 253 4.65E-48 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold TON_0910 5e40dad2130cd36895b34b1bfce53ad5 263 Pfam PF12146 Serine aminopeptidase, S33 14 240 1.7E-68 T 23-10-2018 IPR022742 Serine aminopeptidase, S33 TON_0910 5e40dad2130cd36895b34b1bfce53ad5 263 Gene3D G3DSA:3.40.50.1820 1 258 1.8E-67 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold TON_0185 1426d0705e09adab94e87ee2dcdb4015 67 SUPERFAMILY SSF47113 3 66 2.31E-20 T 23-10-2018 IPR009072 Histone-fold GO:0046982 TON_0185 1426d0705e09adab94e87ee2dcdb4015 67 Gene3D G3DSA:1.10.20.10 1 67 2.5E-24 T 23-10-2018 IPR009072 Histone-fold GO:0046982 TON_0185 1426d0705e09adab94e87ee2dcdb4015 67 Pfam PF00808 Histone-like transcription factor (CBF/NF-Y) and archaeal histone 2 65 5.8E-21 T 23-10-2018 IPR003958 Transcription factor CBF/NF-Y/archaeal histone domain TON_0916 1e0f7f002ce34466921b4792ddd9308d 289 Gene3D G3DSA:3.30.70.20 62 115 9.7E-10 T 23-10-2018 TON_0916 1e0f7f002ce34466921b4792ddd9308d 289 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 3 263 4.1E-20 T 23-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain TON_0916 1e0f7f002ce34466921b4792ddd9308d 289 Pfam PF12800 4Fe-4S binding domain 97 111 0.012 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TON_0916 1e0f7f002ce34466921b4792ddd9308d 289 Pfam PF12837 4Fe-4S binding domain 62 84 1.0E-6 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TON_0916 1e0f7f002ce34466921b4792ddd9308d 289 SUPERFAMILY SSF54862 51 123 7.23E-18 T 23-10-2018 TON_0916 1e0f7f002ce34466921b4792ddd9308d 289 SUPERFAMILY SSF52540 1 284 8.15E-33 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_0916 1e0f7f002ce34466921b4792ddd9308d 289 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 99 110 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TON_0943 afe48acac11c42c72013f478313be7de 526 SUPERFAMILY SSF51717 161 386 5.23E-24 T 23-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TON_0943 afe48acac11c42c72013f478313be7de 526 TIGRFAM TIGR00284 TIGR00284: dihydropteroate synthase-related protein 6 504 2.2E-92 T 23-10-2018 IPR005236 Dihydropteroate synthase-related protein synthase-related protein TON_0245 f18191a9bf98132e8777938f66f0e65f 460 Gene3D G3DSA:3.90.550.10 1 339 7.0E-115 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TON_0245 f18191a9bf98132e8777938f66f0e65f 460 Pfam PF01050 Mannose-6-phosphate isomerase 305 455 1.3E-67 T 23-10-2018 IPR001538 Mannose-6-phosphate isomerase, type II, C-terminal GO:0005976|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882 TON_0245 f18191a9bf98132e8777938f66f0e65f 460 TIGRFAM TIGR01479 GMP_PMI: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase 3 458 2.2E-159 T 23-10-2018 IPR006375 Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase GO:0000271|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882 TON_0245 f18191a9bf98132e8777938f66f0e65f 460 SUPERFAMILY SSF53448 1 266 3.05E-69 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TON_0245 f18191a9bf98132e8777938f66f0e65f 460 Gene3D G3DSA:2.60.120.10 340 444 5.1E-18 T 23-10-2018 IPR014710 RmlC-like jelly roll fold TON_0245 f18191a9bf98132e8777938f66f0e65f 460 Pfam PF00483 Nucleotidyl transferase 2 272 5.4E-61 T 23-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 TON_0245 f18191a9bf98132e8777938f66f0e65f 460 SUPERFAMILY SSF51182 186 459 9.68E-69 T 23-10-2018 IPR011051 RmlC-like cupin domain superfamily TON_1128 a891fcffd225a08432b81e1448ca8e6d 187 Gene3D G3DSA:3.40.109.10 1 185 1.1E-49 T 23-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 TON_1128 a891fcffd225a08432b81e1448ca8e6d 187 SUPERFAMILY SSF55469 1 187 1.44E-47 T 23-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 TON_1128 a891fcffd225a08432b81e1448ca8e6d 187 Pfam PF00881 Nitroreductase family 8 165 2.1E-29 T 23-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 TON_0303 8c5bce811fcb655d1e24ee9a05f8b828 246 Gene3D G3DSA:3.30.390.100 12 219 1.3E-25 T 23-10-2018 TON_0303 8c5bce811fcb655d1e24ee9a05f8b828 246 Pfam PF13938 Putative heavy-metal chelation 9 90 3.2E-15 T 23-10-2018 IPR025251 Domain of unknown function DUF4213 TON_0303 8c5bce811fcb655d1e24ee9a05f8b828 246 Pfam PF04016 Putative heavy-metal chelation 106 242 4.5E-33 T 23-10-2018 IPR007161 Putative heavy-metal chelation domain TON_0303 8c5bce811fcb655d1e24ee9a05f8b828 246 Gene3D G3DSA:3.40.50.11590 105 217 1.3E-25 T 23-10-2018 TON_0303 8c5bce811fcb655d1e24ee9a05f8b828 246 SUPERFAMILY SSF159713 10 244 6.41E-63 T 23-10-2018 TON_0176 c886af4eba983a970d9dd67a8e177bb3 382 SUPERFAMILY SSF52490 46 244 1.07E-70 T 23-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 TON_0176 c886af4eba983a970d9dd67a8e177bb3 382 SMART SM00865 245 361 1.2E-49 T 23-10-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-380320 TON_0176 c886af4eba983a970d9dd67a8e177bb3 382 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 52 212 4.2E-47 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TON_0176 c886af4eba983a970d9dd67a8e177bb3 382 ProSitePatterns PS01135 FtsZ protein signature 2. 136 157 - T 23-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 TON_0176 c886af4eba983a970d9dd67a8e177bb3 382 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 42 364 1.8E-136 T 23-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 TON_0176 c886af4eba983a970d9dd67a8e177bb3 382 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 48 382 38.355 T 23-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 TON_0176 c886af4eba983a970d9dd67a8e177bb3 382 Pfam PF12327 FtsZ family, C-terminal domain 260 352 7.0E-32 T 23-10-2018 IPR024757 Cell division protein FtsZ, C-terminal TON_0176 c886af4eba983a970d9dd67a8e177bb3 382 Gene3D G3DSA:3.30.1330.20 263 369 3.7E-35 T 23-10-2018 IPR037103 Tubulin/FtsZ, C-terminal domain superfamily Reactome: R-HSA-380320 TON_0176 c886af4eba983a970d9dd67a8e177bb3 382 SMART SM00864 52 243 1.8E-108 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TON_0176 c886af4eba983a970d9dd67a8e177bb3 382 SUPERFAMILY SSF55307 245 357 2.52E-38 T 23-10-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 TON_0176 c886af4eba983a970d9dd67a8e177bb3 382 ProSitePatterns PS01134 FtsZ protein signature 1. 83 117 - T 23-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 TON_0176 c886af4eba983a970d9dd67a8e177bb3 382 PRINTS PR00423 Cell division protein FtsZ signature 250 271 8.3E-44 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TON_0176 c886af4eba983a970d9dd67a8e177bb3 382 PRINTS PR00423 Cell division protein FtsZ signature 137 157 8.3E-44 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TON_0176 c886af4eba983a970d9dd67a8e177bb3 382 PRINTS PR00423 Cell division protein FtsZ signature 227 249 8.3E-44 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TON_0176 c886af4eba983a970d9dd67a8e177bb3 382 PRINTS PR00423 Cell division protein FtsZ signature 165 186 8.3E-44 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TON_0176 c886af4eba983a970d9dd67a8e177bb3 382 Gene3D G3DSA:3.40.50.1440 44 258 1.9E-83 T 23-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 TON_1341 eaade77abdc921c2f24a1ed6f55e82c2 114 SUPERFAMILY SSF69695 2 108 1.96E-24 T 23-10-2018 IPR036521 Signal recognition particle, subunit SRP19-like superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 TON_1341 eaade77abdc921c2f24a1ed6f55e82c2 114 Hamap MF_00305 Signal recognition particle 19 kDa protein [srp19]. 5 94 21.485 T 23-10-2018 IPR022938 Signal recognition particle, SRP19 subunit, archaeal-type TON_1341 eaade77abdc921c2f24a1ed6f55e82c2 114 Gene3D G3DSA:3.30.56.30 1 106 1.1E-31 T 23-10-2018 IPR036521 Signal recognition particle, subunit SRP19-like superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 TON_1341 eaade77abdc921c2f24a1ed6f55e82c2 114 Pfam PF01922 SRP19 protein 5 86 4.3E-15 T 23-10-2018 IPR002778 Signal recognition particle, SRP19 subunit GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 TON_0110 daa230ba59d436b5f4bd9efaf191d6bc 57 Pfam PF01192 RNA polymerase Rpb6 5 51 1.1E-10 T 23-10-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 TON_0110 daa230ba59d436b5f4bd9efaf191d6bc 57 ProSitePatterns PS01111 RNA polymerases K / 14 to 18 Kd subunits signature. 5 19 - T 23-10-2018 IPR020708 DNA-directed RNA polymerase, 14-18kDa subunit, conserved site GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 TON_0110 daa230ba59d436b5f4bd9efaf191d6bc 57 Gene3D G3DSA:3.90.940.50 1 57 1.6E-27 T 23-10-2018 TON_0110 daa230ba59d436b5f4bd9efaf191d6bc 57 SUPERFAMILY SSF63562 3 55 1.01E-19 T 23-10-2018 IPR036161 RPB6/omega subunit-like superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 TON_0110 daa230ba59d436b5f4bd9efaf191d6bc 57 PIRSF PIRSF000778 1 57 5.0E-22 T 23-10-2018 IPR006111 Archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 TON_0110 daa230ba59d436b5f4bd9efaf191d6bc 57 Hamap MF_00192 DNA-directed RNA polymerase subunit K [rpoK]. 2 57 21.818 T 23-10-2018 IPR006111 Archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 TON_1700 0c5895901ee717c6ad89e5d1e9b604a6 377 PIRSF PIRSF000390 1 377 3.0E-116 T 23-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase TON_1700 0c5895901ee717c6ad89e5d1e9b604a6 377 Gene3D G3DSA:3.40.640.10 1 249 8.3E-91 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TON_1700 0c5895901ee717c6ad89e5d1e9b604a6 377 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 11 369 1.0E-114 T 23-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase TON_1700 0c5895901ee717c6ad89e5d1e9b604a6 377 Gene3D G3DSA:3.90.1150.10 250 376 3.1E-35 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TON_1700 0c5895901ee717c6ad89e5d1e9b604a6 377 SUPERFAMILY SSF53383 2 374 3.9E-117 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TON_1543 6152c010202bd141faaf84437adf8971 623 SUPERFAMILY SSF82171 23 346 1.83E-21 T 23-10-2018 TON_1543 6152c010202bd141faaf84437adf8971 623 Gene3D G3DSA:3.40.50.1820 354 623 1.5E-84 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold TON_1543 6152c010202bd141faaf84437adf8971 623 Pfam PF07676 WD40-like Beta Propeller Repeat 60 77 0.0024 T 23-10-2018 IPR011659 WD40-like Beta Propeller TON_1543 6152c010202bd141faaf84437adf8971 623 Pfam PF00326 Prolyl oligopeptidase family 397 608 5.1E-52 T 23-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 TON_1543 6152c010202bd141faaf84437adf8971 623 Gene3D G3DSA:2.120.10.30 19 139 4.4E-12 T 23-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like TON_1543 6152c010202bd141faaf84437adf8971 623 SUPERFAMILY SSF53474 353 607 3.08E-58 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold TON_0768 c2913958c5d7eeb577066c4bfb811cdb 264 Pfam PF00005 ABC transporter 20 165 1.4E-27 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TON_0768 c2913958c5d7eeb577066c4bfb811cdb 264 Gene3D G3DSA:3.40.50.300 1 240 3.6E-61 T 23-10-2018 TON_0768 c2913958c5d7eeb577066c4bfb811cdb 264 SUPERFAMILY SSF52540 4 227 1.15E-55 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_0768 c2913958c5d7eeb577066c4bfb811cdb 264 SMART SM00382 28 215 2.4E-15 T 23-10-2018 IPR003593 AAA+ ATPase domain TON_0768 c2913958c5d7eeb577066c4bfb811cdb 264 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TON_1767 be46792f0d54bd29d7af6b7cb0c6a436 319 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TON_1767 be46792f0d54bd29d7af6b7cb0c6a436 319 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 234 298 1.0E-19 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TON_1767 be46792f0d54bd29d7af6b7cb0c6a436 319 SUPERFAMILY SSF52540 33 312 3.22E-68 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_1767 be46792f0d54bd29d7af6b7cb0c6a436 319 Pfam PF00005 ABC transporter 25 182 2.4E-27 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TON_1767 be46792f0d54bd29d7af6b7cb0c6a436 319 Gene3D G3DSA:3.40.50.300 3 319 3.6E-102 T 23-10-2018 TON_1767 be46792f0d54bd29d7af6b7cb0c6a436 319 SMART SM00382 34 240 6.9E-10 T 23-10-2018 IPR003593 AAA+ ATPase domain TON_1767 be46792f0d54bd29d7af6b7cb0c6a436 319 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 232 318 9.3E-31 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TON_0239 dfac2844af0cde17f3dd51eb96ba01cc 266 TIGRFAM TIGR00162 TIGR00162: TIGR00162 family protein 9 265 5.2E-75 T 23-10-2018 IPR004426 Conserved hypothetical protein CHP00062 TON_0239 dfac2844af0cde17f3dd51eb96ba01cc 266 Pfam PF09754 PAC2 family 19 242 1.2E-46 T 23-10-2018 IPR019151 Proteasome assembly chaperone 2 TON_0239 dfac2844af0cde17f3dd51eb96ba01cc 266 Gene3D G3DSA:3.40.50.10900 1 244 2.3E-75 T 23-10-2018 IPR038389 Proteasome assembly chaperone 2 superfamily TON_0239 dfac2844af0cde17f3dd51eb96ba01cc 266 SUPERFAMILY SSF159659 2 252 3.53E-43 T 23-10-2018 TON_0393 3687beb9b21ccbd06383bf1f8d3cfd1f 458 SMART SM00490 330 408 1.5E-12 T 23-10-2018 IPR001650 Helicase, C-terminal TON_0393 3687beb9b21ccbd06383bf1f8d3cfd1f 458 Gene3D G3DSA:3.40.50.300 275 457 5.4E-33 T 23-10-2018 TON_0393 3687beb9b21ccbd06383bf1f8d3cfd1f 458 Pfam PF04851 Type III restriction enzyme, res subunit 96 233 9.2E-18 T 23-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 TON_0393 3687beb9b21ccbd06383bf1f8d3cfd1f 458 SMART SM00487 93 274 3.1E-26 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TON_0393 3687beb9b21ccbd06383bf1f8d3cfd1f 458 Gene3D G3DSA:3.40.50.300 86 263 2.0E-34 T 23-10-2018 TON_0393 3687beb9b21ccbd06383bf1f8d3cfd1f 458 SUPERFAMILY SSF52540 138 421 2.1E-34 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_0393 3687beb9b21ccbd06383bf1f8d3cfd1f 458 Pfam PF00271 Helicase conserved C-terminal domain 305 406 4.0E-11 T 23-10-2018 IPR001650 Helicase, C-terminal TON_0904 f0391a75764826eba17b55bbb6ba5473 594 Gene3D G3DSA:3.20.20.70 1 454 1.2E-164 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TON_0904 f0391a75764826eba17b55bbb6ba5473 594 Gene3D G3DSA:2.40.50.100 522 594 3.5E-29 T 23-10-2018 TON_0904 f0391a75764826eba17b55bbb6ba5473 594 SUPERFAMILY SSF51569 2 299 6.59E-85 T 23-10-2018 TON_0904 f0391a75764826eba17b55bbb6ba5473 594 Pfam PF00364 Biotin-requiring enzyme 528 593 6.5E-25 T 23-10-2018 IPR000089 Biotin/lipoyl attachment TON_0904 f0391a75764826eba17b55bbb6ba5473 594 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 550 567 - T 23-10-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 TON_0904 f0391a75764826eba17b55bbb6ba5473 594 Pfam PF00682 HMGL-like 2 232 4.0E-40 T 23-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 TON_0904 f0391a75764826eba17b55bbb6ba5473 594 SUPERFAMILY SSF51230 519 593 2.22E-25 T 23-10-2018 IPR011053 Single hybrid motif TON_0904 f0391a75764826eba17b55bbb6ba5473 594 Pfam PF02436 Conserved carboxylase domain 290 472 5.8E-56 T 23-10-2018 IPR003379 Carboxylase, conserved domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 TON_0904 f0391a75764826eba17b55bbb6ba5473 594 SUPERFAMILY SSF89000 295 442 1.49E-53 T 23-10-2018 TON_0710 c122d496b9e52d3271801337151bcbaf 419 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 195 359 4.2E-38 T 23-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TON_0710 c122d496b9e52d3271801337151bcbaf 419 SMART SM00283 143 418 7.6E-46 T 23-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TON_0710 c122d496b9e52d3271801337151bcbaf 419 Gene3D G3DSA:1.10.287.950 110 418 2.1E-60 T 23-10-2018 TON_0710 c122d496b9e52d3271801337151bcbaf 419 SUPERFAMILY SSF58104 149 418 1.22E-57 T 23-10-2018 TON_1358 063eb96d828b4f4f054e698aa13f641d 350 SUPERFAMILY SSF53335 165 285 3.03E-8 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TON_1358 063eb96d828b4f4f054e698aa13f641d 350 Gene3D G3DSA:3.40.50.150 101 326 6.9E-86 T 23-10-2018 TON_1358 063eb96d828b4f4f054e698aa13f641d 350 Gene3D G3DSA:1.10.10.10 1 83 1.9E-32 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TON_1358 063eb96d828b4f4f054e698aa13f641d 350 PIRSF PIRSF005895 1 350 5.6E-161 T 23-10-2018 IPR014435 N(4)-bis(aminopropyl)spermidine synthase GO:0006596|GO:0016765 TON_1358 063eb96d828b4f4f054e698aa13f641d 350 Hamap MF_01947 N(4)-bis(aminopropyl)spermidine synthase [bpsA]. 15 350 50.975 T 23-10-2018 IPR014435 N(4)-bis(aminopropyl)spermidine synthase GO:0006596|GO:0016765 TON_1358 063eb96d828b4f4f054e698aa13f641d 350 Pfam PF01861 Protein of unknown function DUF43 106 349 1.3E-119 T 23-10-2018 IPR002723 N(4)-bis(aminopropyl)spermidine synthase, C-terminal TON_1421 0db8a4ef98be11eb364ca63a315e5e95 456 Gene3D G3DSA:3.60.21.10 1 280 2.0E-127 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like TON_1421 0db8a4ef98be11eb364ca63a315e5e95 456 Pfam PF00149 Calcineurin-like phosphoesterase 1 217 1.9E-16 T 23-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 TON_1421 0db8a4ef98be11eb364ca63a315e5e95 456 Gene3D G3DSA:3.30.110.80 238 334 2.0E-127 T 23-10-2018 TON_1421 0db8a4ef98be11eb364ca63a315e5e95 456 SUPERFAMILY SSF56300 1 337 1.35E-60 T 23-10-2018 TON_1421 0db8a4ef98be11eb364ca63a315e5e95 456 Hamap MF_02044 DNA double-strand break repair protein Mre11 [mre11]. 1 409 24.376 T 23-10-2018 IPR032885 DNA double-strand break repair protein Mre11, archaea-type GO:0006302 TON_1103 fe32e84e929b9787d41921a0feb01ec0 150 ProSitePatterns PS00628 Ribosomal protein S19e signature. 87 106 - T 23-10-2018 IPR018277 Ribosomal protein S19e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_1103 fe32e84e929b9787d41921a0feb01ec0 150 ProDom PD003854 RIBOSOMAL 40S RIBONUCLEOPROTEIN S19 S19E 30S MULTIGENE FAMILY S19 SSU 3 115 3.0E-58 T 23-10-2018 IPR001266 Ribosomal protein S19e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_1103 fe32e84e929b9787d41921a0feb01ec0 150 SUPERFAMILY SSF46785 3 150 3.11E-61 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TON_1103 fe32e84e929b9787d41921a0feb01ec0 150 Gene3D G3DSA:1.10.10.2700 1 150 2.6E-66 T 23-10-2018 IPR038111 Ribosomal protein S19e domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_1103 fe32e84e929b9787d41921a0feb01ec0 150 SMART SM01413 3 139 2.0E-91 T 23-10-2018 IPR001266 Ribosomal protein S19e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_1103 fe32e84e929b9787d41921a0feb01ec0 150 Hamap MF_01474 30S ribosomal protein S19e [rps19e]. 1 148 38.035 T 23-10-2018 IPR027548 Ribosomal protein S19e, archaeal GO:0003735|GO:0005840|GO:0006412 TON_1103 fe32e84e929b9787d41921a0feb01ec0 150 Pfam PF01090 Ribosomal protein S19e 3 138 1.8E-58 T 23-10-2018 IPR001266 Ribosomal protein S19e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_1055 ee1f352173ac94b5621bd5390b68b8a9 275 Gene3D G3DSA:1.10.340.30 98 212 1.0E-34 T 23-10-2018 TON_1055 ee1f352173ac94b5621bd5390b68b8a9 275 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 104 246 5.6E-12 T 23-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 TON_1055 ee1f352173ac94b5621bd5390b68b8a9 275 SMART SM00478 108 266 1.1E-19 T 23-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 TON_1055 ee1f352173ac94b5621bd5390b68b8a9 275 SUPERFAMILY SSF48150 87 265 6.28E-34 T 23-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 TON_1055 ee1f352173ac94b5621bd5390b68b8a9 275 Gene3D G3DSA:1.10.1670.40 77 261 1.0E-34 T 23-10-2018 TON_0002 f6751aef5c72b024ddd713dc96f34140 231 Gene3D G3DSA:3.40.50.1000 2 215 3.9E-63 T 23-10-2018 IPR023214 HAD superfamily TON_0002 f6751aef5c72b024ddd713dc96f34140 231 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 140 193 1.7E-6 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TON_0002 f6751aef5c72b024ddd713dc96f34140 231 Gene3D G3DSA:1.10.150.400 14 92 3.9E-63 T 23-10-2018 TON_0002 f6751aef5c72b024ddd713dc96f34140 231 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 142 158 6.0E-7 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TON_0002 f6751aef5c72b024ddd713dc96f34140 231 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 1 12 6.0E-7 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TON_0002 f6751aef5c72b024ddd713dc96f34140 231 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 188 201 6.0E-7 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TON_0002 f6751aef5c72b024ddd713dc96f34140 231 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 108 121 6.0E-7 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TON_0002 f6751aef5c72b024ddd713dc96f34140 231 SUPERFAMILY SSF56784 1 228 3.83E-34 T 23-10-2018 IPR036412 HAD-like superfamily TON_0002 f6751aef5c72b024ddd713dc96f34140 231 Pfam PF13419 Haloacid dehalogenase-like hydrolase 42 199 1.0E-15 T 23-10-2018 TON_0054 85ab8cad0084251bb90b050d86b73161 291 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 248 282 2.8E-13 T 23-10-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain TON_0054 85ab8cad0084251bb90b050d86b73161 291 SUPERFAMILY SSF52343 99 282 1.83E-30 T 23-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain TON_0054 85ab8cad0084251bb90b050d86b73161 291 Pfam PF00970 Oxidoreductase FAD-binding domain 15 102 6.8E-8 T 23-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 TON_0054 85ab8cad0084251bb90b050d86b73161 291 Gene3D G3DSA:2.40.30.10 3 103 7.4E-19 T 23-10-2018 TON_0054 85ab8cad0084251bb90b050d86b73161 291 Pfam PF00175 Oxidoreductase NAD-binding domain 116 229 8.9E-11 T 23-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 TON_0054 85ab8cad0084251bb90b050d86b73161 291 Gene3D G3DSA:3.40.50.80 105 248 2.3E-21 T 23-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain TON_0054 85ab8cad0084251bb90b050d86b73161 291 PIRSF PIRSF006816 5 291 6.3E-83 T 23-10-2018 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 TON_0054 85ab8cad0084251bb90b050d86b73161 291 Gene3D G3DSA:2.10.240.10 249 283 1.1E-8 T 23-10-2018 IPR037117 Dihydroorotate dehydrogenase, electron transfer subunit, Fe-S binding domain superfamily TON_0054 85ab8cad0084251bb90b050d86b73161 291 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 152 163 5.7E-7 T 23-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 TON_0054 85ab8cad0084251bb90b050d86b73161 291 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 140 149 5.7E-7 T 23-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 TON_0054 85ab8cad0084251bb90b050d86b73161 291 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 115 134 5.7E-7 T 23-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 TON_0054 85ab8cad0084251bb90b050d86b73161 291 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 216 224 5.7E-7 T 23-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 TON_0054 85ab8cad0084251bb90b050d86b73161 291 PRINTS PR00410 Phenol hydroxylase reductase family signature 216 224 5.8E-10 T 23-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 TON_0054 85ab8cad0084251bb90b050d86b73161 291 PRINTS PR00410 Phenol hydroxylase reductase family signature 41 53 5.8E-10 T 23-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 TON_0054 85ab8cad0084251bb90b050d86b73161 291 PRINTS PR00410 Phenol hydroxylase reductase family signature 140 149 5.8E-10 T 23-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 TON_0054 85ab8cad0084251bb90b050d86b73161 291 PRINTS PR00410 Phenol hydroxylase reductase family signature 115 134 5.8E-10 T 23-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 TON_0054 85ab8cad0084251bb90b050d86b73161 291 SUPERFAMILY SSF63380 7 104 1.2E-22 T 23-10-2018 IPR017938 Riboflavin synthase-like beta-barrel TON_0546 1bcfe49fa4a5f3b05c5df54f61213230 624 SUPERFAMILY SSF53807 69 333 5.1E-68 T 23-10-2018 TON_0546 1bcfe49fa4a5f3b05c5df54f61213230 624 Gene3D G3DSA:3.40.50.1980 206 334 2.2E-35 T 23-10-2018 TON_0546 1bcfe49fa4a5f3b05c5df54f61213230 624 Gene3D G3DSA:3.40.50.1980 478 604 5.3E-38 T 23-10-2018 TON_0546 1bcfe49fa4a5f3b05c5df54f61213230 624 Pfam PF01497 Periplasmic binding protein 361 579 1.8E-40 T 23-10-2018 IPR002491 ABC transporter periplasmic binding domain TON_0546 1bcfe49fa4a5f3b05c5df54f61213230 624 Pfam PF01497 Periplasmic binding protein 90 308 4.1E-37 T 23-10-2018 IPR002491 ABC transporter periplasmic binding domain TON_0546 1bcfe49fa4a5f3b05c5df54f61213230 624 SUPERFAMILY SSF53807 345 608 5.89E-72 T 23-10-2018 TON_0546 1bcfe49fa4a5f3b05c5df54f61213230 624 Gene3D G3DSA:3.40.50.1980 343 473 1.1E-32 T 23-10-2018 TON_0546 1bcfe49fa4a5f3b05c5df54f61213230 624 Gene3D G3DSA:3.40.50.1980 72 201 4.2E-32 T 23-10-2018 TON_1975 7a8740900a24e40bc3bd557d41811389 140 Pfam PF00535 Glycosyl transferase family 2 7 62 9.5E-10 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TON_1975 7a8740900a24e40bc3bd557d41811389 140 Gene3D G3DSA:3.90.550.10 1 120 5.6E-17 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TON_1975 7a8740900a24e40bc3bd557d41811389 140 SUPERFAMILY SSF53448 4 72 5.06E-17 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TON_0179 f98a318a6e060e07a99e89d1989b2a75 163 SMART SM00649 5 138 2.9E-65 T 23-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 TON_0179 f98a318a6e060e07a99e89d1989b2a75 163 Gene3D G3DSA:1.10.10.250 73 163 3.8E-36 T 23-10-2018 IPR036769 Ribosomal protein L11, C-terminal domain superfamily TON_0179 f98a318a6e060e07a99e89d1989b2a75 163 Pfam PF00298 Ribosomal protein L11, RNA binding domain 70 137 8.6E-23 T 23-10-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 TON_0179 f98a318a6e060e07a99e89d1989b2a75 163 SUPERFAMILY SSF46906 71 142 4.58E-23 T 23-10-2018 IPR036769 Ribosomal protein L11, C-terminal domain superfamily TON_0179 f98a318a6e060e07a99e89d1989b2a75 163 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 1 139 28.153 T 23-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 TON_0179 f98a318a6e060e07a99e89d1989b2a75 163 Pfam PF03946 Ribosomal protein L11, N-terminal domain 5 58 4.3E-23 T 23-10-2018 IPR020784 Ribosomal protein L11, N-terminal TON_0179 f98a318a6e060e07a99e89d1989b2a75 163 SUPERFAMILY SSF54747 3 82 3.79E-26 T 23-10-2018 IPR036796 Ribosomal protein L11/L12, N-terminal domain superfamily TON_0179 f98a318a6e060e07a99e89d1989b2a75 163 ProSitePatterns PS00359 Ribosomal protein L11 signature. 124 139 - T 23-10-2018 IPR020785 Ribosomal protein L11, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0179 f98a318a6e060e07a99e89d1989b2a75 163 Gene3D G3DSA:2.10.260.30 1 69 6.7E-28 T 23-10-2018 TON_0373 82834fd025f67bd685bfba72efda3c08 264 SUPERFAMILY SSF64005 32 259 2.22E-89 T 23-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 TON_0373 82834fd025f67bd685bfba72efda3c08 264 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 209 226 - T 23-10-2018 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199|Reactome: R-HSA-4755609 TON_0373 82834fd025f67bd685bfba72efda3c08 264 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 34 263 2.2E-88 T 23-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 TON_0373 82834fd025f67bd685bfba72efda3c08 264 Gene3D G3DSA:3.40.1180.10 19 264 5.5E-103 T 23-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 TON_0373 82834fd025f67bd685bfba72efda3c08 264 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 34 264 40.367 T 23-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 TON_0373 82834fd025f67bd685bfba72efda3c08 264 Pfam PF01255 Putative undecaprenyl diphosphate synthase 41 263 1.4E-83 T 23-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 TON_1874 7fcf22342b3a13599f265b70a6744cc8 257 Gene3D G3DSA:3.40.50.300 1 250 1.0E-64 T 23-10-2018 TON_1874 7fcf22342b3a13599f265b70a6744cc8 257 Pfam PF00005 ABC transporter 18 165 1.2E-30 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TON_1874 7fcf22342b3a13599f265b70a6744cc8 257 SMART SM00382 25 214 1.2E-19 T 23-10-2018 IPR003593 AAA+ ATPase domain TON_1874 7fcf22342b3a13599f265b70a6744cc8 257 SUPERFAMILY SSF52540 1 227 2.46E-62 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_1874 7fcf22342b3a13599f265b70a6744cc8 257 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TON_1733 0a9aad54bbea3b0936d4f93e4fbb80e9 592 Gene3D G3DSA:3.40.630.30 420 573 3.8E-9 T 23-10-2018 TON_1733 0a9aad54bbea3b0936d4f93e4fbb80e9 592 SMART SM00729 80 375 7.5E-50 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TON_1733 0a9aad54bbea3b0936d4f93e4fbb80e9 592 Pfam PF16199 Radical_SAM C-terminal domain 336 415 2.9E-25 T 23-10-2018 IPR032432 Radical SAM, C-terminal extension Reactome: R-HSA-3214847 TON_1733 0a9aad54bbea3b0936d4f93e4fbb80e9 592 PIRSF PIRSF005669 1 574 6.4E-249 T 23-10-2018 IPR034687 Elongator complex protein 3-like Reactome: R-HSA-3214847 TON_1733 0a9aad54bbea3b0936d4f93e4fbb80e9 592 Pfam PF00583 Acetyltransferase (GNAT) family 450 562 1.2E-8 T 23-10-2018 IPR000182 GNAT domain TON_1733 0a9aad54bbea3b0936d4f93e4fbb80e9 592 Pfam PF04055 Radical SAM superfamily 87 320 3.7E-32 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TON_1733 0a9aad54bbea3b0936d4f93e4fbb80e9 592 SUPERFAMILY SSF102114 86 382 5.49E-35 T 23-10-2018 TON_1733 0a9aad54bbea3b0936d4f93e4fbb80e9 592 Gene3D G3DSA:3.80.30.20 233 383 4.4E-13 T 23-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe TON_1733 0a9aad54bbea3b0936d4f93e4fbb80e9 592 SUPERFAMILY SSF55729 438 569 1.12E-10 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase TON_1733 0a9aad54bbea3b0936d4f93e4fbb80e9 592 TIGRFAM TIGR01211 ELP3: radical SAM enzyme/protein acetyltransferase, ELP3 family 15 573 2.4E-263 T 23-10-2018 IPR034687 Elongator complex protein 3-like Reactome: R-HSA-3214847 TON_0342 dc93d5688c731917f2c8d17165c3722f 170 Gene3D G3DSA:3.30.300.20 46 97 8.1E-10 T 23-10-2018 IPR015946 K homology domain-like, alpha/beta TON_0342 dc93d5688c731917f2c8d17165c3722f 170 SUPERFAMILY SSF54814 39 96 2.81E-8 T 23-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 TON_0342 dc93d5688c731917f2c8d17165c3722f 170 Pfam PF13184 NusA-like KH domain 57 124 1.0E-10 T 23-10-2018 IPR025249 KH domain, NusA-like GO:0003723 TON_0342 dc93d5688c731917f2c8d17165c3722f 170 SMART SM00322 57 119 1.1E-4 T 23-10-2018 IPR004087 K Homology domain GO:0003676 TON_0028 7503156a66e01fc8747adebf3cf73911 236 Pfam PF09377 SBDS protein C-terminal domain 101 210 3.3E-16 T 23-10-2018 IPR018978 Ribosome maturation protein SBDS, C-terminal GO:0042254 TON_0028 7503156a66e01fc8747adebf3cf73911 236 TIGRFAM TIGR00291 RNA_SBDS: rRNA metabolism protein, SBDS family 3 231 8.0E-92 T 23-10-2018 IPR002140 Ribosome maturation protein Sdo1/SBDS GO:0042256 TON_0028 7503156a66e01fc8747adebf3cf73911 236 SUPERFAMILY SSF109728 82 155 6.15E-25 T 23-10-2018 IPR037188 Ribosome maturation protein Sdo1/SBDS, central domain superfamily TON_0028 7503156a66e01fc8747adebf3cf73911 236 SUPERFAMILY SSF89895 4 87 1.2E-25 T 23-10-2018 IPR036786 Ribosome maturation protein SBDS, N-terminal domain superfamily TON_0028 7503156a66e01fc8747adebf3cf73911 236 Pfam PF01172 Shwachman-Bodian-Diamond syndrome (SBDS) protein 8 94 2.9E-25 T 23-10-2018 IPR019783 Ribosome maturation protein SBDS, N-terminal TON_0028 7503156a66e01fc8747adebf3cf73911 236 Gene3D G3DSA:1.10.10.900 88 162 1.4E-30 T 23-10-2018 IPR037188 Ribosome maturation protein Sdo1/SBDS, central domain superfamily TON_0028 7503156a66e01fc8747adebf3cf73911 236 SUPERFAMILY SSF54980 157 228 2.4E-22 T 23-10-2018 IPR035647 EF-G domain III/V-like TON_0028 7503156a66e01fc8747adebf3cf73911 236 ProSitePatterns PS01267 Uncharacterized protein family UPF0023 signature. 37 56 - T 23-10-2018 IPR018023 Ribosome maturation protein SBDS, conserved site TON_0028 7503156a66e01fc8747adebf3cf73911 236 Gene3D G3DSA:3.30.1250.10 8 87 5.3E-31 T 23-10-2018 IPR036786 Ribosome maturation protein SBDS, N-terminal domain superfamily TON_0028 7503156a66e01fc8747adebf3cf73911 236 Gene3D G3DSA:3.30.70.240 163 235 8.0E-29 T 23-10-2018 TON_0144 115bb9a803a34efc5621fb2e5e8e7e15 194 Gene3D G3DSA:3.40.1120.10 1 193 1.0E-90 T 23-10-2018 IPR024794 Ribosomal protein L15e core domain superfamily GO:0003735|GO:0005840 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0144 115bb9a803a34efc5621fb2e5e8e7e15 194 ProSitePatterns PS01194 Ribosomal protein L15e signature. 46 69 - T 23-10-2018 IPR020925 Ribosomal protein L15e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0144 115bb9a803a34efc5621fb2e5e8e7e15 194 SUPERFAMILY SSF54189 1 191 1.01E-87 T 23-10-2018 IPR012678 Ribosomal protein L23/L15e core domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 TON_0144 115bb9a803a34efc5621fb2e5e8e7e15 194 SMART SM01384 2 191 4.0E-135 T 23-10-2018 IPR000439 Ribosomal protein L15e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0144 115bb9a803a34efc5621fb2e5e8e7e15 194 Pfam PF00827 Ribosomal L15 2 189 5.0E-90 T 23-10-2018 IPR000439 Ribosomal protein L15e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0144 115bb9a803a34efc5621fb2e5e8e7e15 194 Hamap MF_00256 50S ribosomal protein L15e [rpl15e]. 1 193 43.665 T 23-10-2018 IPR020926 Ribosomal protein L15e, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 TON_1887 1fafc2b0512a333db47abd4dce94a119 302 Hamap MF_00568 Quinolinate synthase A [nadA]. 4 301 45.878 T 23-10-2018 IPR023066 Quinolinate synthase A, type 2 GO:0016765 MetaCyc: PWY-5316|MetaCyc: PWY-7342 TON_1887 1fafc2b0512a333db47abd4dce94a119 302 Pfam PF02445 Quinolinate synthetase A protein 9 300 1.6E-112 T 23-10-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 TON_1887 1fafc2b0512a333db47abd4dce94a119 302 Gene3D G3DSA:3.40.50.10800 173 257 1.6E-124 T 23-10-2018 TON_1887 1fafc2b0512a333db47abd4dce94a119 302 Gene3D G3DSA:3.40.50.10800 8 282 1.6E-124 T 23-10-2018 TON_1887 1fafc2b0512a333db47abd4dce94a119 302 Gene3D G3DSA:3.40.50.10800 88 300 1.6E-124 T 23-10-2018 TON_1887 1fafc2b0512a333db47abd4dce94a119 302 TIGRFAM TIGR00550 nadA: quinolinate synthetase complex, A subunit 1 302 1.4E-117 T 23-10-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 TON_1887 1fafc2b0512a333db47abd4dce94a119 302 SUPERFAMILY SSF142754 5 301 1.29E-115 T 23-10-2018 IPR036094 Quinolinate synthetase A superfamily GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 TON_1972 2e9943e5a6000f96f4828e1065e3f57b 272 Gene3D G3DSA:3.40.50.150 10 232 9.0E-68 T 23-10-2018 TON_1972 2e9943e5a6000f96f4828e1065e3f57b 272 SUPERFAMILY SSF53335 3 233 4.0E-38 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TON_1972 2e9943e5a6000f96f4828e1065e3f57b 272 Pfam PF13649 Methyltransferase domain 45 139 5.0E-21 T 23-10-2018 TON_1972 2e9943e5a6000f96f4828e1065e3f57b 272 Gene3D G3DSA:2.20.25.110 147 209 9.0E-68 T 23-10-2018 TON_0765 ffa1cf080a4305de8ac2785314b46133 234 Gene3D G3DSA:3.30.1370.10 35 117 4.3E-34 T 23-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 TON_0765 ffa1cf080a4305de8ac2785314b46133 234 SUPERFAMILY SSF54791 134 204 6.14E-18 T 23-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 TON_0765 ffa1cf080a4305de8ac2785314b46133 234 Pfam PF00013 KH domain 142 189 9.7E-6 T 23-10-2018 IPR004088 K Homology domain, type 1 GO:0003723 TON_0765 ffa1cf080a4305de8ac2785314b46133 234 Pfam PF00013 KH domain 39 86 8.9E-9 T 23-10-2018 IPR004088 K Homology domain, type 1 GO:0003723 TON_0765 ffa1cf080a4305de8ac2785314b46133 234 SUPERFAMILY SSF54791 40 114 1.25E-12 T 23-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 TON_0765 ffa1cf080a4305de8ac2785314b46133 234 Gene3D G3DSA:3.30.1370.10 118 222 7.8E-33 T 23-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 TON_0765 ffa1cf080a4305de8ac2785314b46133 234 SMART SM00322 126 193 1.3E-6 T 23-10-2018 IPR004087 K Homology domain GO:0003676 TON_0765 ffa1cf080a4305de8ac2785314b46133 234 SMART SM00322 35 105 3.1E-10 T 23-10-2018 IPR004087 K Homology domain GO:0003676 TON_0765 ffa1cf080a4305de8ac2785314b46133 234 TIGRFAM TIGR03665 arCOG04150: arCOG04150 universal archaeal KH domain protein 41 214 7.7E-69 T 23-10-2018 IPR019964 KH domain protein, archaea TON_0851 cd7fea761619edcf1573bbb64e0a131b 247 Gene3D G3DSA:3.40.50.300 1 241 2.7E-56 T 23-10-2018 TON_0851 cd7fea761619edcf1573bbb64e0a131b 247 TIGRFAM TIGR01978 sufC: FeS assembly ATPase SufC 2 237 7.3E-86 T 23-10-2018 IPR010230 FeS cluster assembly SUF system, ATPase SufC GO:0005524 TON_0851 cd7fea761619edcf1573bbb64e0a131b 247 Pfam PF00005 ABC transporter 17 167 1.3E-21 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TON_0851 cd7fea761619edcf1573bbb64e0a131b 247 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TON_0851 cd7fea761619edcf1573bbb64e0a131b 247 SUPERFAMILY SSF52540 2 225 1.62E-46 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_0851 cd7fea761619edcf1573bbb64e0a131b 247 SMART SM00382 26 217 3.4E-6 T 23-10-2018 IPR003593 AAA+ ATPase domain TON_0003 65fa207bb9d9ab1054587e1269efa102 338 Gene3D G3DSA:3.40.50.10620 101 324 2.2E-66 T 23-10-2018 TON_0003 65fa207bb9d9ab1054587e1269efa102 338 ProDom PD038575 MJECL12 PLASMID PH0156 102 322 3.0E-76 T 23-10-2018 IPR024508 Protein of unknown function DUF3226 TON_0003 65fa207bb9d9ab1054587e1269efa102 338 SUPERFAMILY SSF160945 100 333 3.4E-90 T 23-10-2018 TON_0003 65fa207bb9d9ab1054587e1269efa102 338 Gene3D G3DSA:1.10.3490.10 235 323 2.2E-66 T 23-10-2018 TON_0003 65fa207bb9d9ab1054587e1269efa102 338 Pfam PF11536 Protein of unknown function (DUF3226) 102 333 1.1E-76 T 23-10-2018 IPR024508 Protein of unknown function DUF3226 TON_0042 2390947195129b4eff1643f5e3071a7f 143 Gene3D G3DSA:3.30.70.3150 41 131 9.8E-32 T 23-10-2018 TON_0042 2390947195129b4eff1643f5e3071a7f 143 Pfam PF01873 Domain found in IF2B/IF5 25 136 1.5E-35 T 23-10-2018 IPR002735 Translation initiation factor IF2/IF5 GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 TON_0042 2390947195129b4eff1643f5e3071a7f 143 SUPERFAMILY SSF100966 9 110 4.45E-27 T 23-10-2018 IPR016189 Translation initiation factor IF2/IF5, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 TON_0042 2390947195129b4eff1643f5e3071a7f 143 Hamap MF_00232 Translation initiation factor 2 subunit beta [eif2b]. 9 143 32.892 T 23-10-2018 IPR004458 Translation initiation factor 2, beta subunit GO:0003743|GO:0006413 TON_0042 2390947195129b4eff1643f5e3071a7f 143 SUPERFAMILY SSF75689 107 142 8.37E-12 T 23-10-2018 IPR016190 Translation initiation factor IF2/IF5, zinc-binding GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 TON_0042 2390947195129b4eff1643f5e3071a7f 143 SMART SM00653 30 137 3.1E-58 T 23-10-2018 IPR002735 Translation initiation factor IF2/IF5 GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 TON_0042 2390947195129b4eff1643f5e3071a7f 143 TIGRFAM TIGR00311 aIF-2beta: putative translation initiation factor aIF-2, beta subunit 10 141 2.8E-50 T 23-10-2018 IPR004458 Translation initiation factor 2, beta subunit GO:0003743|GO:0006413 TON_0335 5b68e8ff2b0d6c6172d5c013036e538c 241 Pfam PF00491 Arginase family 56 223 1.3E-18 T 23-10-2018 IPR006035 Ureohydrolase GO:0046872 TON_0335 5b68e8ff2b0d6c6172d5c013036e538c 241 Gene3D G3DSA:3.40.800.10 31 240 2.3E-19 T 23-10-2018 TON_0335 5b68e8ff2b0d6c6172d5c013036e538c 241 PIRSF PIRSF036979 26 228 2.3E-16 T 23-10-2018 IPR006035 Ureohydrolase GO:0046872 TON_0335 5b68e8ff2b0d6c6172d5c013036e538c 241 SUPERFAMILY SSF52768 56 225 5.04E-26 T 23-10-2018 IPR023696 Ureohydrolase domain superfamily TON_0940 67ef93b8eebcffce058930199211dddc 87 Hamap MF_01245 UPF0248 protein . 10 79 18.161 T 23-10-2018 IPR007547 Uncharacterised protein family UPF0248 TON_0940 67ef93b8eebcffce058930199211dddc 87 Pfam PF04457 Protein of unknown function (DUF504) 26 77 2.9E-14 T 23-10-2018 IPR007547 Uncharacterised protein family UPF0248 TON_1083 592c99788011bba7281e42af8d652803 480 PIRSF PIRSF001589 1 374 2.9E-56 T 23-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 TON_1083 592c99788011bba7281e42af8d652803 480 PIRSF PIRSF001589 368 479 9.6E-19 T 23-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 TON_1083 592c99788011bba7281e42af8d652803 480 Gene3D G3DSA:3.60.20.10 2 212 2.0E-42 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TON_1083 592c99788011bba7281e42af8d652803 480 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 363 2.4E-81 T 23-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 TON_1083 592c99788011bba7281e42af8d652803 480 Pfam PF00733 Asparagine synthase 364 460 2.0E-20 T 23-10-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 TON_1083 592c99788011bba7281e42af8d652803 480 Pfam PF00733 Asparagine synthase 229 361 1.1E-33 T 23-10-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 TON_1083 592c99788011bba7281e42af8d652803 480 SUPERFAMILY SSF56235 12 208 3.0E-42 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TON_1083 592c99788011bba7281e42af8d652803 480 SUPERFAMILY SSF52402 218 468 6.4E-57 T 23-10-2018 TON_1083 592c99788011bba7281e42af8d652803 480 Pfam PF13537 Glutamine amidotransferase domain 61 179 4.7E-25 T 23-10-2018 IPR017932 Glutamine amidotransferase type 2 domain TON_1083 592c99788011bba7281e42af8d652803 480 Gene3D G3DSA:3.40.50.620 214 479 1.4E-72 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TON_1667 f51135466b54e39fc973a66ee6cbc6d7 225 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 17 217 4.1E-72 T 23-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 TON_1667 f51135466b54e39fc973a66ee6cbc6d7 225 SUPERFAMILY SSF56529 12 222 3.4E-81 T 23-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 TON_1667 f51135466b54e39fc973a66ee6cbc6d7 225 Gene3D G3DSA:3.90.850.10 3 221 3.7E-92 T 23-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 TON_1024 5d4c0f3e72c22e42c7e34556456a1f29 191 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 16 135 1.3E-20 T 23-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_1024 5d4c0f3e72c22e42c7e34556456a1f29 191 SUPERFAMILY SSF56770 4 150 1.44E-41 T 23-10-2018 TON_1024 5d4c0f3e72c22e42c7e34556456a1f29 191 Gene3D G3DSA:3.40.50.12280 1 153 5.7E-42 T 23-10-2018 TON_1049 7a1d973e56a5149ce16d90d0b44838de 333 TIGRFAM TIGR00724 urea_amlyse_rel: biotin-dependent carboxylase uncharacterized domain 1 307 9.8E-112 T 23-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B TON_1049 7a1d973e56a5149ce16d90d0b44838de 333 Pfam PF02626 Carboxyltransferase domain, subdomain A and B 24 283 1.1E-84 T 23-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B TON_1049 7a1d973e56a5149ce16d90d0b44838de 333 SMART SM00797 23 300 1.3E-144 T 23-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B TON_1049 7a1d973e56a5149ce16d90d0b44838de 333 SUPERFAMILY SSF50891 174 290 2.12E-12 T 23-10-2018 IPR029000 Cyclophilin-like domain superfamily TON_1049 7a1d973e56a5149ce16d90d0b44838de 333 Gene3D G3DSA:2.40.100.10 171 311 4.2E-50 T 23-10-2018 IPR029000 Cyclophilin-like domain superfamily TON_0227 3c44d90648b16cd284a8f57a4ba9e48a 421 Pfam PF04894 Archaeal Nre, N-terminal 19 284 7.7E-104 T 23-10-2018 IPR006978 Archaeal Nre, N-terminal TON_0227 3c44d90648b16cd284a8f57a4ba9e48a 421 Hamap MF_02096 DNA repair protein. 1 406 39.999 T 23-10-2018 IPR033167 Archaeal Nre GO:0006281 TON_0227 3c44d90648b16cd284a8f57a4ba9e48a 421 Pfam PF04895 Archaeal Nre, C-terminal 296 406 3.7E-37 T 23-10-2018 IPR006979 Archaeal Nre, C-terminal TON_0954 746f40f040f26d50ef1f4dd3d8669c00 123 ProSitePatterns PS01082 Ribosomal protein L7Ae signature. 70 87 - T 23-10-2018 IPR004037 Ribosomal protein L7Ae conserved site GO:0042254|GO:1990904 Reactome: R-HSA-6791226 TON_0954 746f40f040f26d50ef1f4dd3d8669c00 123 SUPERFAMILY SSF55315 4 120 1.24E-39 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like TON_0954 746f40f040f26d50ef1f4dd3d8669c00 123 TIGRFAM TIGR03677 eL8_ribo: ribosomal protein eL8 6 121 2.5E-57 T 23-10-2018 IPR022481 Ribosomal protein L7Ae, archaea GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 TON_0954 746f40f040f26d50ef1f4dd3d8669c00 123 PRINTS PR00884 Ribosomal protein HS6 signature 77 87 2.7E-30 T 23-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 TON_0954 746f40f040f26d50ef1f4dd3d8669c00 123 PRINTS PR00884 Ribosomal protein HS6 signature 6 17 2.7E-30 T 23-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 TON_0954 746f40f040f26d50ef1f4dd3d8669c00 123 PRINTS PR00884 Ribosomal protein HS6 signature 40 50 2.7E-30 T 23-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 TON_0954 746f40f040f26d50ef1f4dd3d8669c00 123 PRINTS PR00884 Ribosomal protein HS6 signature 50 61 2.7E-30 T 23-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 TON_0954 746f40f040f26d50ef1f4dd3d8669c00 123 PRINTS PR00884 Ribosomal protein HS6 signature 91 107 2.7E-30 T 23-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 TON_0954 746f40f040f26d50ef1f4dd3d8669c00 123 Hamap MF_00326 50S ribosomal protein L7Ae [rpl7ae]. 3 122 35.212 T 23-10-2018 IPR022481 Ribosomal protein L7Ae, archaea GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 TON_0954 746f40f040f26d50ef1f4dd3d8669c00 123 Pfam PF01248 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family 18 110 6.3E-32 T 23-10-2018 IPR004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45 TON_0954 746f40f040f26d50ef1f4dd3d8669c00 123 Gene3D G3DSA:3.30.1330.30 1 123 4.1E-43 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like TON_0954 746f40f040f26d50ef1f4dd3d8669c00 123 PRINTS PR00881 Ribosomal protein L7A/RS6 family signature 32 46 1.6E-22 T 23-10-2018 IPR018492 Ribosomal protein L7Ae/L8/Nhp2 family TON_0954 746f40f040f26d50ef1f4dd3d8669c00 123 PRINTS PR00881 Ribosomal protein L7A/RS6 family signature 67 77 1.6E-22 T 23-10-2018 IPR018492 Ribosomal protein L7Ae/L8/Nhp2 family TON_0954 746f40f040f26d50ef1f4dd3d8669c00 123 PRINTS PR00881 Ribosomal protein L7A/RS6 family signature 77 91 1.6E-22 T 23-10-2018 IPR018492 Ribosomal protein L7Ae/L8/Nhp2 family TON_0954 746f40f040f26d50ef1f4dd3d8669c00 123 PRINTS PR00881 Ribosomal protein L7A/RS6 family signature 51 64 1.6E-22 T 23-10-2018 IPR018492 Ribosomal protein L7Ae/L8/Nhp2 family TON_1086 ce71b36db19bbda8b4aceb7c413b9fcf 339 SUPERFAMILY SSF55821 9 209 2.04E-69 T 23-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily TON_1086 ce71b36db19bbda8b4aceb7c413b9fcf 339 Pfam PF03481 Putative GTP-binding controlling metal-binding 200 333 1.1E-27 T 23-10-2018 IPR005145 Putative GTP-binding controlling metal-binding domain TON_1086 ce71b36db19bbda8b4aceb7c413b9fcf 339 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 12 207 1.1E-67 T 23-10-2018 IPR006070 YrdC-like domain GO:0003725 TON_1086 ce71b36db19bbda8b4aceb7c413b9fcf 339 Gene3D G3DSA:3.40.50.11030 216 339 1.2E-39 T 23-10-2018 IPR038385 Threonylcarbamoyl-AMP synthase, C-terminal domain superfamily TON_1086 ce71b36db19bbda8b4aceb7c413b9fcf 339 PIRSF PIRSF004930 1 338 2.4E-133 T 23-10-2018 IPR010923 tRNA threonylcarbamoyladenosine biosynthesis protein SUA5 TON_1086 ce71b36db19bbda8b4aceb7c413b9fcf 339 Gene3D G3DSA:3.90.870.10 3 212 1.7E-86 T 23-10-2018 TON_1086 ce71b36db19bbda8b4aceb7c413b9fcf 339 Pfam PF01300 Telomere recombination 22 196 7.7E-61 T 23-10-2018 IPR006070 YrdC-like domain GO:0003725 TON_0044 bf976f126d4b5e5a18ad8f4b69adc250 164 Pfam PF05916 GINS complex protein 28 147 2.4E-8 T 23-10-2018 IPR021151 GINS subunit, domain A Reactome: R-HSA-176974 TON_0044 bf976f126d4b5e5a18ad8f4b69adc250 164 Gene3D G3DSA:1.20.58.2050 1 164 1.1E-82 T 23-10-2018 IPR038437 GINS complex, subunit Psf3 superfamily Reactome: R-HSA-176974 TON_0187 2f058c95802babd19fca0ce88d6f727a 133 Hamap MF_01095 UPF0292 protein . 3 123 33.576 T 23-10-2018 IPR022972 Uncharacterised protein family UPF0292 TON_0187 2f058c95802babd19fca0ce88d6f727a 133 Gene3D G3DSA:3.40.1360.10 3 117 1.5E-23 T 23-10-2018 TON_0187 2f058c95802babd19fca0ce88d6f727a 133 SUPERFAMILY SSF110455 19 95 1.03E-6 T 23-10-2018 TON_0187 2f058c95802babd19fca0ce88d6f727a 133 Pfam PF01751 Toprim domain 23 86 3.0E-6 T 23-10-2018 IPR006171 TOPRIM domain TON_0187 2f058c95802babd19fca0ce88d6f727a 133 SMART SM00493 20 90 5.1E-9 T 23-10-2018 IPR006171 TOPRIM domain TON_0146 00867214dadf4ff024071531dfcfd62d 223 ProDom PD016938 P COMPONENT RIBONUCLEASE RNASE HYDROLASE PROCESSING TRNA SUBUNIT SIMILAR P/RNASE 119 211 2.0E-38 T 23-10-2018 TON_0146 00867214dadf4ff024071531dfcfd62d 223 Gene3D G3DSA:3.20.20.140 4 221 7.5E-97 T 23-10-2018 TON_0146 00867214dadf4ff024071531dfcfd62d 223 SUPERFAMILY SSF89550 15 219 4.32E-32 T 23-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 TON_0146 00867214dadf4ff024071531dfcfd62d 223 Hamap MF_00756 Ribonuclease P protein component 3 [rnp3]. 13 223 23.099 T 23-10-2018 IPR023539 Ribonuclease P, protein component 3, archaeal GO:0001682|GO:0004526 TON_0146 00867214dadf4ff024071531dfcfd62d 223 Pfam PF01876 RNase P subunit p30 46 212 4.1E-32 T 23-10-2018 IPR002738 RNase P subunit p30 GO:0004540|GO:0008033 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 TON_0888 4b854f8e93b72fc3a7be134a2ed5ffc5 262 Gene3D G3DSA:1.10.3730.10 155 257 1.5E-37 T 23-10-2018 TON_0888 4b854f8e93b72fc3a7be134a2ed5ffc5 262 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 2 91 8.2E-21 T 23-10-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal TON_0888 4b854f8e93b72fc3a7be134a2ed5ffc5 262 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 1 256 26.396 T 23-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 TON_0888 4b854f8e93b72fc3a7be134a2ed5ffc5 262 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 3 254 1.0E-78 T 23-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 TON_0888 4b854f8e93b72fc3a7be134a2ed5ffc5 262 PIRSF PIRSF000193 1 259 8.4E-75 T 23-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 TON_0888 4b854f8e93b72fc3a7be134a2ed5ffc5 262 SUPERFAMILY SSF48179 151 257 3.57E-35 T 23-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 TON_0888 4b854f8e93b72fc3a7be134a2ed5ffc5 262 SUPERFAMILY SSF51735 2 150 8.33E-34 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TON_0888 4b854f8e93b72fc3a7be134a2ed5ffc5 262 Gene3D G3DSA:3.40.50.720 1 154 1.4E-48 T 23-10-2018 TON_0888 4b854f8e93b72fc3a7be134a2ed5ffc5 262 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 152 254 4.3E-37 T 23-10-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 TON_0041 4e2602e5a7b679cca3716db75ea10e92 522 SUPERFAMILY SSF52096 3 257 1.61E-79 T 23-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TON_0041 4e2602e5a7b679cca3716db75ea10e92 522 Gene3D G3DSA:3.90.226.10 262 522 7.5E-97 T 23-10-2018 TON_0041 4e2602e5a7b679cca3716db75ea10e92 522 SUPERFAMILY SSF52096 244 522 9.74E-93 T 23-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TON_0041 4e2602e5a7b679cca3716db75ea10e92 522 Gene3D G3DSA:3.90.226.10 1 260 3.5E-98 T 23-10-2018 TON_0041 4e2602e5a7b679cca3716db75ea10e92 522 Pfam PF01039 Carboxyl transferase domain 28 520 1.1E-202 T 23-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 TON_0410 2bd190355029af3bf300b9ea55bbc548 184 Pfam PF02915 Rubrerythrin 42 171 4.0E-12 T 23-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 TON_0410 2bd190355029af3bf300b9ea55bbc548 184 Gene3D G3DSA:1.20.1260.10 20 175 6.4E-27 T 23-10-2018 IPR012347 Ferritin-like TON_0410 2bd190355029af3bf300b9ea55bbc548 184 SUPERFAMILY SSF47240 26 171 9.47E-19 T 23-10-2018 IPR009078 Ferritin-like superfamily TON_0853 d5f01d1c37a3dc72af47c2dd646dec9d 363 Hamap MF_00021 tRNA sulfurtransferase [thiI]. 1 363 108.87 T 23-10-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 KEGG: 00730+2.8.1.4 TON_0853 d5f01d1c37a3dc72af47c2dd646dec9d 363 SMART SM00981 67 153 2.4E-19 T 23-10-2018 IPR004114 THUMP domain GO:0003723 TON_0853 d5f01d1c37a3dc72af47c2dd646dec9d 363 Gene3D G3DSA:3.30.2130.30 1 162 8.0E-46 T 23-10-2018 TON_0853 d5f01d1c37a3dc72af47c2dd646dec9d 363 SUPERFAMILY SSF52402 162 362 2.87E-45 T 23-10-2018 TON_0853 d5f01d1c37a3dc72af47c2dd646dec9d 363 SUPERFAMILY SSF143437 1 161 7.32E-42 T 23-10-2018 TON_0853 d5f01d1c37a3dc72af47c2dd646dec9d 363 TIGRFAM TIGR00342 TIGR00342: tRNA sulfurtransferase ThiI 2 335 4.8E-99 T 23-10-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 KEGG: 00730+2.8.1.4 TON_0853 d5f01d1c37a3dc72af47c2dd646dec9d 363 Pfam PF02568 Thiamine biosynthesis protein (ThiI) 163 347 4.8E-52 T 23-10-2018 IPR020536 Thil, AANH domain GO:0004810 KEGG: 00730+2.8.1.4 TON_0853 d5f01d1c37a3dc72af47c2dd646dec9d 363 Pfam PF02926 THUMP domain 26 152 7.3E-24 T 23-10-2018 IPR004114 THUMP domain GO:0003723 TON_0853 d5f01d1c37a3dc72af47c2dd646dec9d 363 Gene3D G3DSA:3.40.50.620 163 362 2.2E-54 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TON_0587 80bad1055244d119d3002bbbc71327aa 396 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 34 270 3.8E-76 T 23-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 TON_0587 80bad1055244d119d3002bbbc71327aa 396 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 294 388 2.3E-18 T 23-10-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II TON_0587 80bad1055244d119d3002bbbc71327aa 396 Gene3D G3DSA:3.40.50.970 12 211 3.3E-76 T 23-10-2018 TON_0587 80bad1055244d119d3002bbbc71327aa 396 SUPERFAMILY SSF52518 23 277 8.83E-66 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold TON_0587 80bad1055244d119d3002bbbc71327aa 396 Gene3D G3DSA:3.40.50.920 282 395 4.1E-22 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TON_0587 80bad1055244d119d3002bbbc71327aa 396 SUPERFAMILY SSF52922 286 393 1.28E-22 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TON_0774 2f713621eeca1b8be669c029515bbbe7 602 SUPERFAMILY SSF56235 2 227 1.89E-73 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TON_0774 2f713621eeca1b8be669c029515bbbe7 602 Gene3D G3DSA:3.40.50.10490 250 601 3.0E-139 T 23-10-2018 TON_0774 2f713621eeca1b8be669c029515bbbe7 602 Gene3D G3DSA:3.40.50.10490 442 587 3.0E-139 T 23-10-2018 TON_0774 2f713621eeca1b8be669c029515bbbe7 602 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 602 40.877 T 23-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 TON_0774 2f713621eeca1b8be669c029515bbbe7 602 Gene3D G3DSA:3.60.20.10 2 238 1.2E-77 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TON_0774 2f713621eeca1b8be669c029515bbbe7 602 Pfam PF01380 SIS domain 457 584 3.1E-21 T 23-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 TON_0774 2f713621eeca1b8be669c029515bbbe7 602 Pfam PF01380 SIS domain 284 413 2.4E-35 T 23-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 TON_0774 2f713621eeca1b8be669c029515bbbe7 602 Pfam PF13522 Glutamine amidotransferase domain 67 187 1.9E-21 T 23-10-2018 TON_0774 2f713621eeca1b8be669c029515bbbe7 602 SUPERFAMILY SSF53697 247 602 7.89E-112 T 23-10-2018 TON_0774 2f713621eeca1b8be669c029515bbbe7 602 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 602 5.8E-248 T 23-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 TON_0409 9a9fd30eab3730adac19504bf21576f6 272 Gene3D G3DSA:3.40.50.150 2 195 1.5E-64 T 23-10-2018 TON_0409 9a9fd30eab3730adac19504bf21576f6 272 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 15 265 8.2E-76 T 23-10-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 TON_0409 9a9fd30eab3730adac19504bf21576f6 272 SMART SM00650 30 193 5.8E-80 T 23-10-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 TON_0409 9a9fd30eab3730adac19504bf21576f6 272 Pfam PF00398 Ribosomal RNA adenine dimethylase 15 237 6.5E-53 T 23-10-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm TON_0409 9a9fd30eab3730adac19504bf21576f6 272 Gene3D G3DSA:1.10.8.100 196 271 6.8E-10 T 23-10-2018 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201|Reactome: R-HSA-6793080 TON_0409 9a9fd30eab3730adac19504bf21576f6 272 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 14 267 46.225 T 23-10-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 TON_0409 9a9fd30eab3730adac19504bf21576f6 272 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 46 73 - T 23-10-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 TON_0409 9a9fd30eab3730adac19504bf21576f6 272 SUPERFAMILY SSF53335 11 264 4.15E-63 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TON_0627 beff714064dbe523595d890b69cbd34e 340 Gene3D G3DSA:3.40.630.10 11 333 3.4E-113 T 23-10-2018 TON_0627 beff714064dbe523595d890b69cbd34e 340 PIRSF PIRSF001123 1 339 6.5E-38 T 23-10-2018 IPR008007 Peptidase M42 TON_0627 beff714064dbe523595d890b69cbd34e 340 SUPERFAMILY SSF53187 2 335 4.72E-48 T 23-10-2018 TON_0627 beff714064dbe523595d890b69cbd34e 340 Gene3D G3DSA:2.40.30.40 70 164 3.4E-113 T 23-10-2018 IPR023367 Peptidase M42, domain 2 TON_0627 beff714064dbe523595d890b69cbd34e 340 Pfam PF05343 M42 glutamyl aminopeptidase 48 328 8.9E-72 T 23-10-2018 IPR008007 Peptidase M42 TON_0627 beff714064dbe523595d890b69cbd34e 340 SUPERFAMILY SSF101821 67 178 1.1E-26 T 23-10-2018 TON_1740 8800c185b7498ddcc2ec9505a8cd0e62 248 TIGRFAM TIGR03877 thermo_KaiC_1: KaiC domain protein, Ph0284 family 2 239 4.8E-141 T 23-10-2018 IPR022475 Uncharacterised protein family UPF0273, KaiC-like TON_1740 8800c185b7498ddcc2ec9505a8cd0e62 248 Pfam PF06745 KaiC 5 237 2.0E-91 T 23-10-2018 IPR014774 KaiC-like domain TON_1740 8800c185b7498ddcc2ec9505a8cd0e62 248 Gene3D G3DSA:3.40.50.300 1 247 4.6E-82 T 23-10-2018 TON_1740 8800c185b7498ddcc2ec9505a8cd0e62 248 Hamap MF_01076 UPF0273 protein . 2 245 62.971 T 23-10-2018 IPR022475 Uncharacterised protein family UPF0273, KaiC-like TON_1740 8800c185b7498ddcc2ec9505a8cd0e62 248 SUPERFAMILY SSF52540 2 236 6.93E-50 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_1740 8800c185b7498ddcc2ec9505a8cd0e62 248 PRINTS PR01874 DNA repair protein radA signature 56 73 4.4E-9 T 23-10-2018 TON_1740 8800c185b7498ddcc2ec9505a8cd0e62 248 PRINTS PR01874 DNA repair protein radA signature 14 42 4.4E-9 T 23-10-2018 TON_1740 8800c185b7498ddcc2ec9505a8cd0e62 248 PRINTS PR01874 DNA repair protein radA signature 167 195 4.4E-9 T 23-10-2018 TON_1976 7035111aa657f1b171b930a8f5eb4779 154 Gene3D G3DSA:1.10.10.10 9 80 1.1E-8 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TON_1976 7035111aa657f1b171b930a8f5eb4779 154 Pfam PF12802 MarR family 7 65 8.5E-9 T 23-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TON_1976 7035111aa657f1b171b930a8f5eb4779 154 Gene3D G3DSA:3.30.70.920 81 154 2.6E-10 T 23-10-2018 TON_1976 7035111aa657f1b171b930a8f5eb4779 154 SUPERFAMILY SSF46785 31 138 7.26E-11 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TON_1976 7035111aa657f1b171b930a8f5eb4779 154 Pfam PF01037 Lrp/AsnC ligand binding domain 87 152 3.1E-8 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain TON_1976 7035111aa657f1b171b930a8f5eb4779 154 SMART SM00419 21 72 4.3E-10 T 23-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 TON_0647 24cd72cadc6c0527e490a9a0df7daef7 364 Gene3D G3DSA:1.20.1260.10 4 143 4.5E-7 T 23-10-2018 IPR012347 Ferritin-like TON_0647 24cd72cadc6c0527e490a9a0df7daef7 364 Pfam PF02915 Rubrerythrin 12 137 7.4E-7 T 23-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 TON_0647 24cd72cadc6c0527e490a9a0df7daef7 364 SUPERFAMILY SSF47240 4 139 3.08E-16 T 23-10-2018 IPR009078 Ferritin-like superfamily TON_0647 24cd72cadc6c0527e490a9a0df7daef7 364 Pfam PF01988 VIT family 149 353 1.3E-46 T 23-10-2018 IPR008217 Ccc1 family TON_1420 180562b692a6d8387371d480a82dacbd 586 SUPERFAMILY SSF52540 150 540 5.71E-38 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_1420 180562b692a6d8387371d480a82dacbd 586 Pfam PF01935 Domain of unknown function DUF87 150 374 1.0E-52 T 23-10-2018 IPR002789 Helicase HerA, central domain TON_1420 180562b692a6d8387371d480a82dacbd 586 Gene3D G3DSA:3.40.50.300 136 279 6.5E-21 T 23-10-2018 TON_1420 180562b692a6d8387371d480a82dacbd 586 Pfam PF09378 HAS barrel domain 8 110 1.2E-19 T 23-10-2018 IPR018538 Helicase HerA, barrel domain TON_1420 180562b692a6d8387371d480a82dacbd 586 Pfam PF05872 Bacterial protein of unknown function (DUF853) 432 526 1.7E-4 T 23-10-2018 IPR033186 Helicase HerA-like C-terminal TON_1365 6445141607f105bede23409a6d5deb5f 302 Pfam PF00953 Glycosyl transferase family 4 70 215 9.9E-33 T 23-10-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 TON_0799 7d24cb2bb19e63dae74fbe7f871fbf7b 245 SUPERFAMILY SSF82861 2 75 1.44E-7 T 23-10-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 TON_0799 7d24cb2bb19e63dae74fbe7f871fbf7b 245 Gene3D G3DSA:2.30.30.60 92 141 5.7E-15 T 23-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily TON_0799 7d24cb2bb19e63dae74fbe7f871fbf7b 245 SUPERFAMILY SSF50182 76 142 8.83E-15 T 23-10-2018 IPR010920 LSM domain superfamily TON_0799 7d24cb2bb19e63dae74fbe7f871fbf7b 245 SUPERFAMILY SSF82689 143 241 1.31E-33 T 23-10-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 TON_0799 7d24cb2bb19e63dae74fbe7f871fbf7b 245 Gene3D G3DSA:3.30.70.100 142 236 9.2E-31 T 23-10-2018 TON_0799 7d24cb2bb19e63dae74fbe7f871fbf7b 245 Pfam PF00924 Mechanosensitive ion channel 35 231 5.9E-49 T 23-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 TON_1873 ce8805f021fab50937f0ccbf389bf9be 348 Pfam PF01032 FecCD transport family 14 341 2.9E-88 T 23-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 TON_1873 ce8805f021fab50937f0ccbf389bf9be 348 SUPERFAMILY SSF81345 7 341 5.75E-78 T 23-10-2018 IPR037294 ABC transporter, BtuC-like TON_1873 ce8805f021fab50937f0ccbf389bf9be 348 Gene3D G3DSA:1.10.3470.10 2 345 1.5E-97 T 23-10-2018 IPR037294 ABC transporter, BtuC-like TON_1961 de24c6d6fb27b8c1755c54402d5e0af5 281 Pfam PF01261 Xylose isomerase-like TIM barrel 30 239 1.1E-18 T 23-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain TON_1961 de24c6d6fb27b8c1755c54402d5e0af5 281 Gene3D G3DSA:3.20.20.150 12 281 1.0E-41 T 23-10-2018 TON_1961 de24c6d6fb27b8c1755c54402d5e0af5 281 SUPERFAMILY SSF51658 7 278 3.65E-60 T 23-10-2018 IPR036237 Xylose isomerase-like superfamily TON_1961 de24c6d6fb27b8c1755c54402d5e0af5 281 SMART SM00518 4 276 1.7E-87 T 23-10-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 TON_1013 462dadad3c131c53607d30644e32ad69 282 Hamap MF_02055 Tyrosine recombinase XerA [xerA]. 4 274 41.985 T 23-10-2018 IPR033686 Tyrosine recombinase XerA TON_1013 462dadad3c131c53607d30644e32ad69 282 Gene3D G3DSA:1.10.150.130 2 90 1.2E-21 T 23-10-2018 IPR010998 Integrase/recombinase, N-terminal TON_1013 462dadad3c131c53607d30644e32ad69 282 SUPERFAMILY SSF56349 5 270 3.24E-61 T 23-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 TON_1013 462dadad3c131c53607d30644e32ad69 282 Gene3D G3DSA:1.10.443.10 91 282 4.1E-77 T 23-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 TON_1013 462dadad3c131c53607d30644e32ad69 282 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 8 77 2.6E-8 T 23-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 TON_1013 462dadad3c131c53607d30644e32ad69 282 Pfam PF00589 Phage integrase family 99 262 9.0E-50 T 23-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 TON_0135 23af633565356225595df41ec86b30ed 374 SUPERFAMILY SSF51395 32 368 4.55E-81 T 23-10-2018 TON_0135 23af633565356225595df41ec86b30ed 374 Gene3D G3DSA:3.20.20.70 10 374 2.1E-128 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TON_0135 23af633565356225595df41ec86b30ed 374 TIGRFAM TIGR02151 IPP_isom_2: isopentenyl-diphosphate delta-isomerase, type 2 13 352 7.6E-132 T 23-10-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 TON_0135 23af633565356225595df41ec86b30ed 374 PIRSF PIRSF003314 7 363 2.3E-133 T 23-10-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 TON_0135 23af633565356225595df41ec86b30ed 374 Pfam PF01070 FMN-dependent dehydrogenase 186 346 5.9E-16 T 23-10-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 Reactome: R-HSA-9033241 TON_0135 23af633565356225595df41ec86b30ed 374 Pfam PF01070 FMN-dependent dehydrogenase 14 105 5.5E-9 T 23-10-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 Reactome: R-HSA-9033241 TON_0135 23af633565356225595df41ec86b30ed 374 SMART SM01240 30 349 5.4E-4 T 23-10-2018 TON_0135 23af633565356225595df41ec86b30ed 374 Hamap MF_00354 Isopentenyl-diphosphate delta-isomerase [fni]. 10 353 41.134 T 23-10-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 TON_0016 aea302ef6f744df0eb108a8501cec64d 240 SUPERFAMILY SSF52540 3 235 3.34E-72 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_0016 aea302ef6f744df0eb108a8501cec64d 240 Pfam PF00005 ABC transporter 19 163 6.6E-34 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TON_0016 aea302ef6f744df0eb108a8501cec64d 240 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TON_0016 aea302ef6f744df0eb108a8501cec64d 240 Gene3D G3DSA:3.40.50.300 1 238 7.5E-77 T 23-10-2018 TON_0016 aea302ef6f744df0eb108a8501cec64d 240 SMART SM00382 28 212 3.6E-14 T 23-10-2018 IPR003593 AAA+ ATPase domain TON_1743 337e8770769b57d95f8875b7fd2b17e7 305 Pfam PF02355 Protein export membrane protein 130 295 1.7E-29 T 23-10-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial TON_1743 337e8770769b57d95f8875b7fd2b17e7 305 SUPERFAMILY SSF82866 123 293 5.75E-24 T 23-10-2018 TON_1743 337e8770769b57d95f8875b7fd2b17e7 305 Hamap MF_01464_A Protein-export membrane protein SecF [secF]. 28 300 25.637 T 23-10-2018 IPR024921 Protein-export membrane protein SecF, archaeal GO:0016021|GO:0065002 TON_1743 337e8770769b57d95f8875b7fd2b17e7 305 Gene3D G3DSA:1.20.1640.10 112 301 3.2E-15 T 23-10-2018 TON_1720 b32471f927c3ad335a3e5c4fde68e1dc 380 Pfam PF00999 Sodium/hydrogen exchanger family 9 375 2.6E-67 T 23-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 TON_1720 b32471f927c3ad335a3e5c4fde68e1dc 380 Gene3D G3DSA:1.20.1530.20 1 380 2.9E-100 T 23-10-2018 IPR038770 Sodium/solute symporter superfamily TON_0536 63ee4d44209ac4c20682e761b08fa713 291 PIRSF PIRSF006816 13 290 1.5E-83 T 23-10-2018 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 TON_0536 63ee4d44209ac4c20682e761b08fa713 291 Gene3D G3DSA:2.10.240.10 247 284 2.3E-7 T 23-10-2018 IPR037117 Dihydroorotate dehydrogenase, electron transfer subunit, Fe-S binding domain superfamily TON_0536 63ee4d44209ac4c20682e761b08fa713 291 Pfam PF00970 Oxidoreductase FAD-binding domain 31 110 3.4E-8 T 23-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 TON_0536 63ee4d44209ac4c20682e761b08fa713 291 SUPERFAMILY SSF63380 11 115 9.85E-24 T 23-10-2018 IPR017938 Riboflavin synthase-like beta-barrel TON_0536 63ee4d44209ac4c20682e761b08fa713 291 SUPERFAMILY SSF52343 107 282 5.63E-32 T 23-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain TON_0536 63ee4d44209ac4c20682e761b08fa713 291 Gene3D G3DSA:2.40.30.10 17 111 5.2E-20 T 23-10-2018 TON_0536 63ee4d44209ac4c20682e761b08fa713 291 PRINTS PR00410 Phenol hydroxylase reductase family signature 215 223 1.7E-7 T 23-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 TON_0536 63ee4d44209ac4c20682e761b08fa713 291 PRINTS PR00410 Phenol hydroxylase reductase family signature 123 142 1.7E-7 T 23-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 TON_0536 63ee4d44209ac4c20682e761b08fa713 291 PRINTS PR00410 Phenol hydroxylase reductase family signature 49 61 1.7E-7 T 23-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 TON_0536 63ee4d44209ac4c20682e761b08fa713 291 Pfam PF00175 Oxidoreductase NAD-binding domain 124 228 1.9E-13 T 23-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 TON_0536 63ee4d44209ac4c20682e761b08fa713 291 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 247 283 8.8E-13 T 23-10-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain TON_0536 63ee4d44209ac4c20682e761b08fa713 291 Gene3D G3DSA:3.40.50.80 114 245 2.1E-22 T 23-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain TON_1432 52c00e50c47a22ee5dc9169ca3fb5abc 448 Gene3D G3DSA:3.40.50.720 3 132 5.9E-9 T 23-10-2018 TON_1432 52c00e50c47a22ee5dc9169ca3fb5abc 448 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 241 299 4.2E-5 T 23-10-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain TON_1432 52c00e50c47a22ee5dc9169ca3fb5abc 448 SUPERFAMILY SSF52540 125 294 9.73E-12 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_1432 52c00e50c47a22ee5dc9169ca3fb5abc 448 Gene3D G3DSA:3.40.50.300 211 304 1.5E-7 T 23-10-2018 TON_0343 090503916b1539e09325583b955ccab0 443 Pfam PF00152 tRNA synthetases class II (D, K and N) 123 437 3.3E-95 T 23-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 TON_0343 090503916b1539e09325583b955ccab0 443 Pfam PF01336 OB-fold nucleic acid binding domain 24 103 1.9E-11 T 23-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 TON_0343 090503916b1539e09325583b955ccab0 443 PRINTS PR01042 Aspartyl-tRNA synthetase signature 209 222 4.4E-23 T 23-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 TON_0343 090503916b1539e09325583b955ccab0 443 PRINTS PR01042 Aspartyl-tRNA synthetase signature 192 204 4.4E-23 T 23-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 TON_0343 090503916b1539e09325583b955ccab0 443 PRINTS PR01042 Aspartyl-tRNA synthetase signature 398 412 4.4E-23 T 23-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 TON_0343 090503916b1539e09325583b955ccab0 443 PRINTS PR01042 Aspartyl-tRNA synthetase signature 358 374 4.4E-23 T 23-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 TON_0343 090503916b1539e09325583b955ccab0 443 Gene3D G3DSA:3.30.930.10 112 443 1.8E-121 T 23-10-2018 TON_0343 090503916b1539e09325583b955ccab0 443 SUPERFAMILY SSF50249 6 106 1.3E-26 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold TON_0343 090503916b1539e09325583b955ccab0 443 Gene3D G3DSA:2.40.50.140 6 110 3.3E-27 T 23-10-2018 TON_0343 090503916b1539e09325583b955ccab0 443 SUPERFAMILY SSF55681 101 442 6.51E-98 T 23-10-2018 TON_0343 090503916b1539e09325583b955ccab0 443 Hamap MF_02075 Aspartate--tRNA(Asp) ligase [aspS]. 7 443 43.485 T 23-10-2018 IPR004523 Aspartate-tRNA synthetase, type 2 GO:0000166|GO:0004815|GO:0005524|GO:0005737|GO:0006422 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 TON_0343 090503916b1539e09325583b955ccab0 443 TIGRFAM TIGR00458 aspS_nondisc: aspartate--tRNA(Asn) ligase 10 443 1.6E-183 T 23-10-2018 IPR004523 Aspartate-tRNA synthetase, type 2 GO:0000166|GO:0004815|GO:0005524|GO:0005737|GO:0006422 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 TON_1132 b1cf43d70560e9a97cbefc5604004478 306 SUPERFAMILY SSF52518 4 169 4.12E-51 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold TON_1132 b1cf43d70560e9a97cbefc5604004478 306 Pfam PF02780 Transketolase, C-terminal domain 177 297 2.3E-28 T 23-10-2018 IPR033248 Transketolase, C-terminal domain TON_1132 b1cf43d70560e9a97cbefc5604004478 306 Gene3D G3DSA:3.40.50.920 177 306 1.6E-33 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TON_1132 b1cf43d70560e9a97cbefc5604004478 306 SUPERFAMILY SSF52922 174 305 1.07E-31 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TON_1132 b1cf43d70560e9a97cbefc5604004478 306 Gene3D G3DSA:3.40.50.970 2 176 1.4E-58 T 23-10-2018 TON_1132 b1cf43d70560e9a97cbefc5604004478 306 SMART SM00861 3 168 2.1E-48 T 23-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain TON_1132 b1cf43d70560e9a97cbefc5604004478 306 Pfam PF02779 Transketolase, pyrimidine binding domain 5 163 8.2E-35 T 23-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain TON_1139 11fe64e9432161b6f2b876b6e68d6214 356 SUPERFAMILY SSF103263 3 350 9.81E-120 T 23-10-2018 IPR035904 Chorismate synthase AroC superfamily KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 TON_1139 11fe64e9432161b6f2b876b6e68d6214 356 Gene3D G3DSA:3.60.150.10 1 353 1.5E-129 T 23-10-2018 IPR035904 Chorismate synthase AroC superfamily KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 TON_1139 11fe64e9432161b6f2b876b6e68d6214 356 Hamap MF_00300 Chorismate synthase [aroC]. 4 351 34.73 T 23-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 TON_1139 11fe64e9432161b6f2b876b6e68d6214 356 Pfam PF01264 Chorismate synthase 5 344 6.8E-120 T 23-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 TON_1139 11fe64e9432161b6f2b876b6e68d6214 356 ProSitePatterns PS00789 Chorismate synthase signature 3. 318 334 - T 23-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 TON_1139 11fe64e9432161b6f2b876b6e68d6214 356 TIGRFAM TIGR00033 aroC: chorismate synthase 5 347 9.7E-116 T 23-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 TON_1139 11fe64e9432161b6f2b876b6e68d6214 356 ProSitePatterns PS00788 Chorismate synthase signature 2. 118 134 - T 23-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 TON_1139 11fe64e9432161b6f2b876b6e68d6214 356 PIRSF PIRSF001456 1 354 8.4E-134 T 23-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 TON_0079 3dbe6809b4a1be6fa3b736c511ed785a 183 SUPERFAMILY SSF55282 15 180 2.17E-56 T 23-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0079 3dbe6809b4a1be6fa3b736c511ed785a 183 Pfam PF00673 ribosomal L5P family C-terminus 72 171 6.6E-26 T 23-10-2018 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0079 3dbe6809b4a1be6fa3b736c511ed785a 183 PIRSF PIRSF002161 2 180 3.8E-56 T 23-10-2018 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0079 3dbe6809b4a1be6fa3b736c511ed785a 183 Pfam PF00281 Ribosomal protein L5 16 68 1.3E-19 T 23-10-2018 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0079 3dbe6809b4a1be6fa3b736c511ed785a 183 Hamap MF_01333_A 50S ribosomal protein L5 [rplE]. 14 181 42.804 T 23-10-2018 IPR022804 Ribosomal protein L5, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 TON_0079 3dbe6809b4a1be6fa3b736c511ed785a 183 Gene3D G3DSA:3.30.1440.10 10 181 1.7E-71 T 23-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0734 49496a1cc354f72086fe88a31089e1e1 98 SMART SM00418 10 88 3.7E-11 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TON_0734 49496a1cc354f72086fe88a31089e1e1 98 Pfam PF12840 Helix-turn-helix domain 11 64 4.7E-14 T 23-10-2018 TON_0734 49496a1cc354f72086fe88a31089e1e1 98 SUPERFAMILY SSF46785 5 93 6.45E-22 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TON_0734 49496a1cc354f72086fe88a31089e1e1 98 Gene3D G3DSA:1.10.10.10 5 97 5.9E-21 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TON_0533 62cdfdc36f57653d6c1c27b090e0305f 149 SUPERFAMILY SSF53163 1 148 7.59E-31 T 23-10-2018 IPR023430 Peptidase HybD-like domain superfamily TON_0533 62cdfdc36f57653d6c1c27b090e0305f 149 TIGRFAM TIGR00072 hydrog_prot: hydrogenase maturation protease 4 146 7.0E-31 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 TON_0533 62cdfdc36f57653d6c1c27b090e0305f 149 Pfam PF01750 Hydrogenase maturation protease 28 144 7.5E-20 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 TON_0533 62cdfdc36f57653d6c1c27b090e0305f 149 PRINTS PR00446 Hydrogen uptake protein signature 63 79 2.5E-6 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 TON_0533 62cdfdc36f57653d6c1c27b090e0305f 149 PRINTS PR00446 Hydrogen uptake protein signature 3 15 2.5E-6 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 TON_0533 62cdfdc36f57653d6c1c27b090e0305f 149 PRINTS PR00446 Hydrogen uptake protein signature 15 26 2.5E-6 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 TON_0533 62cdfdc36f57653d6c1c27b090e0305f 149 PRINTS PR00446 Hydrogen uptake protein signature 51 61 2.5E-6 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 TON_0533 62cdfdc36f57653d6c1c27b090e0305f 149 Gene3D G3DSA:3.40.50.1450 1 148 7.2E-35 T 23-10-2018 IPR023430 Peptidase HybD-like domain superfamily TON_0763 5cc150e2e108a2d9d6f454774cbf7d17 386 Pfam PF04406 Type IIB DNA topoisomerase 83 151 2.0E-19 T 23-10-2018 IPR013049 Spo11/DNA topoisomerase VI, subunit A, N-terminal GO:0003677|GO:0003824|GO:0005524|GO:0005694|GO:0006259 Reactome: R-HSA-912446 TON_0763 5cc150e2e108a2d9d6f454774cbf7d17 386 Gene3D G3DSA:3.40.1360.10 156 385 1.8E-65 T 23-10-2018 TON_0763 5cc150e2e108a2d9d6f454774cbf7d17 386 Gene3D G3DSA:1.10.10.10 15 155 1.6E-52 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TON_0763 5cc150e2e108a2d9d6f454774cbf7d17 386 SUPERFAMILY SSF56726 81 383 1.83E-79 T 23-10-2018 IPR036078 Spo11/DNA topoisomerase VI subunit A superfamily GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 TON_0763 5cc150e2e108a2d9d6f454774cbf7d17 386 Hamap MF_00132 Type 2 DNA topoisomerase 6 subunit A [top6A]. 17 385 40.719 T 23-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 TON_0763 5cc150e2e108a2d9d6f454774cbf7d17 386 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 147 162 6.2E-29 T 23-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 TON_0763 5cc150e2e108a2d9d6f454774cbf7d17 386 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 226 247 6.2E-29 T 23-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 TON_0763 5cc150e2e108a2d9d6f454774cbf7d17 386 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 107 118 6.2E-29 T 23-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 TON_0763 5cc150e2e108a2d9d6f454774cbf7d17 386 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 129 146 6.2E-29 T 23-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 TON_0763 5cc150e2e108a2d9d6f454774cbf7d17 386 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 202 219 6.2E-29 T 23-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 TON_0763 5cc150e2e108a2d9d6f454774cbf7d17 386 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 258 274 6.2E-29 T 23-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 TON_0763 5cc150e2e108a2d9d6f454774cbf7d17 386 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 49 69 1.4E-48 T 23-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 TON_0763 5cc150e2e108a2d9d6f454774cbf7d17 386 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 232 252 1.4E-48 T 23-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 TON_0763 5cc150e2e108a2d9d6f454774cbf7d17 386 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 123 140 1.4E-48 T 23-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 TON_0763 5cc150e2e108a2d9d6f454774cbf7d17 386 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 356 379 1.4E-48 T 23-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 TON_0763 5cc150e2e108a2d9d6f454774cbf7d17 386 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 176 194 1.4E-48 T 23-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 TON_0947 d552c9dd527ea9d2c85d9c3ce7e13642 419 Gene3D G3DSA:3.40.1350.30 113 261 1.8E-94 T 23-10-2018 TON_0947 d552c9dd527ea9d2c85d9c3ce7e13642 419 Gene3D G3DSA:2.40.50.140 2 62 2.1E-13 T 23-10-2018 TON_0947 d552c9dd527ea9d2c85d9c3ce7e13642 419 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 11 411 1.5E-67 T 23-10-2018 TON_0947 d552c9dd527ea9d2c85d9c3ce7e13642 419 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 344 419 2.6E-14 T 23-10-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 TON_0947 d552c9dd527ea9d2c85d9c3ce7e13642 419 Pfam PF02475 Met-10+ like-protein 276 332 3.0E-8 T 23-10-2018 IPR030382 SAM-dependent methyltransferase TRM5/TYW2-type Reactome: R-HSA-6782861 TON_0947 d552c9dd527ea9d2c85d9c3ce7e13642 419 SUPERFAMILY SSF53335 61 418 6.55E-67 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TON_0947 d552c9dd527ea9d2c85d9c3ce7e13642 419 SUPERFAMILY SSF50249 4 59 1.03E-7 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold TON_0947 d552c9dd527ea9d2c85d9c3ce7e13642 419 Gene3D G3DSA:3.40.50.150 74 413 1.8E-94 T 23-10-2018 TON_1467 b59b3570ff147937f4efb7c03a6ad4c2 179 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 93 170 1.5E-23 T 23-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 TON_1467 b59b3570ff147937f4efb7c03a6ad4c2 179 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 140 146 - T 23-10-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 TON_1467 b59b3570ff147937f4efb7c03a6ad4c2 179 Gene3D G3DSA:1.10.10.10 90 175 7.2E-31 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TON_1467 b59b3570ff147937f4efb7c03a6ad4c2 179 ProDom PD068053 METHYLTRANSFERASE DNA METHYLATED-DNA--PROTEIN-CYSTEINE 6-O- O-6-METHYLGUANINE-DNA- REPAIR MGMT DAMAGE ALKYLTRANSFERASE METHYLGUANINE-DNA 1 97 8.0E-18 T 23-10-2018 IPR015236 Domain of unknown function DUF1938 GO:0005737 TON_1467 b59b3570ff147937f4efb7c03a6ad4c2 179 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 91 168 4.6E-25 T 23-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 TON_1467 b59b3570ff147937f4efb7c03a6ad4c2 179 Gene3D G3DSA:3.30.160.70 1 89 9.1E-20 T 23-10-2018 TON_1467 b59b3570ff147937f4efb7c03a6ad4c2 179 Pfam PF09153 Domain of unknown function (DUF1938) 1 85 6.5E-30 T 23-10-2018 IPR015236 Domain of unknown function DUF1938 GO:0005737 TON_1467 b59b3570ff147937f4efb7c03a6ad4c2 179 SUPERFAMILY SSF46767 91 170 5.36E-22 T 23-10-2018 IPR036217 Methylated DNA-protein cysteine methyltransferase, DNA binding domain Reactome: R-HSA-5657655 TON_1467 b59b3570ff147937f4efb7c03a6ad4c2 179 SUPERFAMILY SSF53155 1 87 1.73E-24 T 23-10-2018 IPR036631 Methylated DNA-protein cysteine methyltransferase domain superfamily GO:0003908|GO:0006281 Reactome: R-HSA-5657655 TON_0842 289f24cb15997d6f3da3a1313147427d 267 SUPERFAMILY SSF103481 39 122 3.92E-15 T 23-10-2018 TON_0842 289f24cb15997d6f3da3a1313147427d 267 Pfam PF00892 EamA-like transporter family 8 119 3.0E-18 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TON_0842 289f24cb15997d6f3da3a1313147427d 267 Pfam PF00892 EamA-like transporter family 132 265 6.8E-16 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TON_0842 289f24cb15997d6f3da3a1313147427d 267 SUPERFAMILY SSF103481 172 266 6.54E-9 T 23-10-2018 TON_1671 5d6696b035008d896d4901b55c70d5ae 365 SMART SM00981 86 182 1.3E-13 T 23-10-2018 IPR004114 THUMP domain GO:0003723 TON_1671 5d6696b035008d896d4901b55c70d5ae 365 Gene3D G3DSA:3.40.50.150 190 365 9.0E-52 T 23-10-2018 TON_1671 5d6696b035008d896d4901b55c70d5ae 365 SUPERFAMILY SSF143437 96 182 1.6E-10 T 23-10-2018 TON_1671 5d6696b035008d896d4901b55c70d5ae 365 SUPERFAMILY SSF53335 179 359 7.93E-36 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TON_1671 5d6696b035008d896d4901b55c70d5ae 365 Pfam PF02926 THUMP domain 32 182 1.1E-29 T 23-10-2018 IPR004114 THUMP domain GO:0003723 TON_1671 5d6696b035008d896d4901b55c70d5ae 365 Gene3D G3DSA:3.30.2130.30 1 189 5.6E-85 T 23-10-2018 TON_1671 5d6696b035008d896d4901b55c70d5ae 365 ProSitePatterns PS01261 Uncharacterized protein family UPF0020 signature. 223 234 - T 23-10-2018 IPR000241 Putative RNA methylase domain TON_1671 5d6696b035008d896d4901b55c70d5ae 365 Pfam PF01170 Putative RNA methylase family UPF0020 191 358 2.8E-36 T 23-10-2018 IPR000241 Putative RNA methylase domain TON_0999 298fabe3665dadaa965a8e28b7237415 389 Pfam PF01769 Divalent cation transporter 256 379 6.9E-17 T 23-10-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 TON_0999 298fabe3665dadaa965a8e28b7237415 389 Pfam PF01769 Divalent cation transporter 53 175 3.8E-22 T 23-10-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 TON_0999 298fabe3665dadaa965a8e28b7237415 389 SUPERFAMILY SSF161093 217 387 8.63E-27 T 23-10-2018 IPR036739 SLC41 divalent cation transporters, integral membrane domain superfamily GO:0006812|GO:0008324 TON_0999 298fabe3665dadaa965a8e28b7237415 389 Gene3D G3DSA:1.10.357.20 5 182 5.9E-11 T 23-10-2018 IPR038048 Magnesium transporter MgtE, transmembrane domain TON_0999 298fabe3665dadaa965a8e28b7237415 389 Gene3D G3DSA:1.10.357.20 206 387 1.6E-13 T 23-10-2018 IPR038048 Magnesium transporter MgtE, transmembrane domain TON_0999 298fabe3665dadaa965a8e28b7237415 389 SUPERFAMILY SSF161093 8 181 2.62E-32 T 23-10-2018 IPR036739 SLC41 divalent cation transporters, integral membrane domain superfamily GO:0006812|GO:0008324 TON_0007 14f0cabbc578b5ea09b09c16538904df 741 SUPERFAMILY SSF50249 225 296 2.57E-10 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold TON_0007 14f0cabbc578b5ea09b09c16538904df 741 Gene3D G3DSA:2.10.230.10 1 87 3.9E-7 T 23-10-2018 TON_0007 14f0cabbc578b5ea09b09c16538904df 741 Gene3D G3DSA:2.40.50.140 128 202 3.8E-13 T 23-10-2018 TON_0007 14f0cabbc578b5ea09b09c16538904df 741 Gene3D G3DSA:3.90.1640.30 333 530 3.0E-9 T 23-10-2018 TON_0007 14f0cabbc578b5ea09b09c16538904df 741 Pfam PF00575 S1 RNA binding domain 130 193 2.1E-9 T 23-10-2018 IPR003029 S1 domain GO:0003676 TON_0007 14f0cabbc578b5ea09b09c16538904df 741 SUPERFAMILY SSF50249 121 197 1.95E-11 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold TON_0007 14f0cabbc578b5ea09b09c16538904df 741 SUPERFAMILY SSF64182 336 734 3.4E-42 T 23-10-2018 IPR038763 DHH phosphoesterase superfamily TON_0007 14f0cabbc578b5ea09b09c16538904df 741 SMART SM00316 131 196 5.1E-14 T 23-10-2018 IPR022967 RNA-binding domain, S1 TON_0007 14f0cabbc578b5ea09b09c16538904df 741 SUPERFAMILY SSF57938 5 32 9.42E-5 T 23-10-2018 IPR036410 Heat shock protein DnaJ, cysteine-rich domain superfamily TON_0007 14f0cabbc578b5ea09b09c16538904df 741 Pfam PF01336 OB-fold nucleic acid binding domain 227 296 4.1E-10 T 23-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 TON_0007 14f0cabbc578b5ea09b09c16538904df 741 Gene3D G3DSA:2.40.50.140 218 304 2.4E-7 T 23-10-2018 TON_1406 3c04a955d5956c1441af39ba6aafaf5b 211 Gene3D G3DSA:3.60.15.10 1 200 2.1E-48 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TON_1406 3c04a955d5956c1441af39ba6aafaf5b 211 SUPERFAMILY SSF56281 1 198 2.75E-38 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TON_1406 3c04a955d5956c1441af39ba6aafaf5b 211 SMART SM00849 7 175 1.4E-19 T 23-10-2018 IPR001279 Metallo-beta-lactamase TON_1406 3c04a955d5956c1441af39ba6aafaf5b 211 Pfam PF13483 Beta-lactamase superfamily domain 3 175 4.6E-29 T 23-10-2018 TON_0520 c6201f7a5ce383381a7fee76bf5ce9e7 200 Pfam PF01015 Ribosomal S3Ae family 11 198 1.4E-66 T 23-10-2018 IPR001593 Ribosomal protein S3Ae GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0520 c6201f7a5ce383381a7fee76bf5ce9e7 200 Hamap MF_00359 30S ribosomal protein S3Ae [rps3ae]. 8 198 36.834 T 23-10-2018 IPR030838 30S ribosomal protein S3Ae GO:0003735|GO:0005840|GO:0006412 TON_0520 c6201f7a5ce383381a7fee76bf5ce9e7 200 ProSitePatterns PS01191 Ribosomal protein S3Ae signature. 47 59 - T 23-10-2018 IPR018281 Ribosomal protein S3Ae, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0520 c6201f7a5ce383381a7fee76bf5ce9e7 200 SMART SM01397 8 198 2.9E-100 T 23-10-2018 IPR001593 Ribosomal protein S3Ae GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_1610 813261f2206b75cd7e7091720f70db76 405 TIGRFAM TIGR04292 heavy_Cys_CGP: heavy-Cys/CGP-CTERM domain protein 20 405 8.0E-178 T 23-10-2018 IPR027556 Heavy-Cys/GCP-CTERM domain protein TON_1610 813261f2206b75cd7e7091720f70db76 405 TIGRFAM TIGR04289 heavy_Cys: eight-cysteine-cluster domain 145 198 9.2E-23 T 23-10-2018 IPR027553 Eight-cysteine-cluster domain TON_1610 813261f2206b75cd7e7091720f70db76 405 TIGRFAM TIGR04288 CGP_CTERM: CGP-CTERM domain 387 405 1.9E-5 T 23-10-2018 IPR027552 CGP-CTERM domain TON_0371 2d6c548f58005b7679dc213ccaab33f1 133 Gene3D G3DSA:3.40.1350.10 2 129 1.7E-39 T 23-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 TON_0371 2d6c548f58005b7679dc213ccaab33f1 133 ProDom PD015874 RESOLVASE HOLLIDAY JUNCTION ARCHAEAL HOLLIDAY-JUNCTION TYPE MJ0497 ORF-C21_024 PF1503 NEQ424 10 126 8.0E-31 T 23-10-2018 IPR014428 Holliday junction resolvase Hjc, archaeal TON_0371 2d6c548f58005b7679dc213ccaab33f1 133 PIRSF PIRSF004985 1 126 7.4E-41 T 23-10-2018 IPR014428 Holliday junction resolvase Hjc, archaeal TON_0371 2d6c548f58005b7679dc213ccaab33f1 133 Pfam PF01870 Archaeal holliday junction resolvase (hjc) 9 94 6.6E-31 T 23-10-2018 IPR002732 Holliday junction resolvase Hjc TON_0371 2d6c548f58005b7679dc213ccaab33f1 133 Hamap MF_01490 Holliday junction resolvase Hjc [hjc]. 2 125 37.541 T 23-10-2018 IPR014428 Holliday junction resolvase Hjc, archaeal TON_0371 2d6c548f58005b7679dc213ccaab33f1 133 SUPERFAMILY SSF52980 3 109 2.55E-29 T 23-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 TON_0804 4b22893e9734a7bbc3f98cec43a1a990 473 PIRSF PIRSF004919 1 472 4.5E-149 T 23-10-2018 IPR025502 TldD TON_0804 4b22893e9734a7bbc3f98cec43a1a990 473 Pfam PF01523 Putative modulator of DNA gyrase 19 325 8.1E-59 T 23-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 TON_0804 4b22893e9734a7bbc3f98cec43a1a990 473 SUPERFAMILY SSF111283 1 468 8.76E-106 T 23-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 TON_0804 4b22893e9734a7bbc3f98cec43a1a990 473 Gene3D G3DSA:3.30.2290.10 1 195 1.2E-27 T 23-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal TON_1052 3dce12ed3379a2bf84af7142449aec5a 161 Pfam PF17146 PIN domain of ribonuclease 3 85 8.3E-20 T 23-10-2018 IPR033411 Ribonuclease, PIN domain Reactome: R-HSA-6791226 TON_1052 3dce12ed3379a2bf84af7142449aec5a 161 Gene3D G3DSA:2.20.28.10 117 154 7.3E-20 T 23-10-2018 TON_1052 3dce12ed3379a2bf84af7142449aec5a 161 Gene3D G3DSA:3.40.50.1010 1 116 4.3E-43 T 23-10-2018 TON_1052 3dce12ed3379a2bf84af7142449aec5a 161 SUPERFAMILY SSF88723 18 112 3.48E-8 T 23-10-2018 IPR029060 PIN-like domain superfamily TON_1052 3dce12ed3379a2bf84af7142449aec5a 161 SMART SM00670 1 98 0.0074 T 23-10-2018 IPR002716 PIN domain TON_0968 9a234920267f1608a94f0ef5f6297e50 810 Pfam PF08351 Domain of unknown function (DUF1726) 129 221 6.0E-33 T 23-10-2018 IPR013562 tRNA(Met) cytidine acetyltransferase TmcA, N-terminal Reactome: R-HSA-6790901 TON_0968 9a234920267f1608a94f0ef5f6297e50 810 Gene3D G3DSA:3.40.630.30 457 662 2.1E-55 T 23-10-2018 TON_0968 9a234920267f1608a94f0ef5f6297e50 810 Gene3D G3DSA:3.40.50.11040 24 247 2.7E-11 T 23-10-2018 TON_0968 9a234920267f1608a94f0ef5f6297e50 810 Pfam PF05127 Helicase 285 458 5.9E-56 T 23-10-2018 IPR007807 Helicase domain Reactome: R-HSA-6790901 TON_0968 9a234920267f1608a94f0ef5f6297e50 810 Pfam PF13718 GNAT acetyltransferase 2 498 614 4.4E-33 T 23-10-2018 IPR000182 GNAT domain TON_0968 9a234920267f1608a94f0ef5f6297e50 810 Hamap MF_01886 tRNA(Met) cytidine acetyltransferase TmcA [tmcA]. 39 807 48.633 T 23-10-2018 IPR024914 tRNA(Met) cytidine acetyltransferase TmcA GO:0000049|GO:0002101|GO:0051391|GO:0051392 TON_0968 9a234920267f1608a94f0ef5f6297e50 810 SUPERFAMILY SSF52540 227 397 3.68E-8 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_0968 9a234920267f1608a94f0ef5f6297e50 810 SUPERFAMILY SSF55729 490 644 1.77E-10 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase TON_0968 9a234920267f1608a94f0ef5f6297e50 810 Gene3D G3DSA:3.40.50.12320 281 448 4.5E-34 T 23-10-2018 TON_1405 7e605fb89797017c0ffb47ae1d1a36d8 127 Pfam PF04266 ASCH domain 15 106 3.1E-11 T 23-10-2018 IPR007374 ASCH domain TON_1405 7e605fb89797017c0ffb47ae1d1a36d8 127 SMART SM01022 13 107 1.5E-5 T 23-10-2018 IPR007374 ASCH domain TON_1405 7e605fb89797017c0ffb47ae1d1a36d8 127 SUPERFAMILY SSF88697 9 118 4.8E-28 T 23-10-2018 IPR015947 PUA-like superfamily TON_1405 7e605fb89797017c0ffb47ae1d1a36d8 127 Gene3D G3DSA:2.30.130.30 10 109 8.6E-32 T 23-10-2018 TON_1443 1be236432e0af0c8c02c91158f4d2011 580 Gene3D G3DSA:3.40.50.300 1 166 2.5E-13 T 23-10-2018 TON_1443 1be236432e0af0c8c02c91158f4d2011 580 Pfam PF00515 Tetratricopeptide repeat 485 513 2.7E-7 T 23-10-2018 IPR001440 Tetratricopeptide repeat 1 GO:0005515 TON_1443 1be236432e0af0c8c02c91158f4d2011 580 SUPERFAMILY SSF52540 10 234 1.37E-21 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_1443 1be236432e0af0c8c02c91158f4d2011 580 Gene3D G3DSA:1.25.40.10 371 576 5.5E-26 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TON_1443 1be236432e0af0c8c02c91158f4d2011 580 SMART SM00028 432 465 0.047 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TON_1443 1be236432e0af0c8c02c91158f4d2011 580 SMART SM00028 483 516 8.1E-6 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TON_1443 1be236432e0af0c8c02c91158f4d2011 580 SMART SM00028 523 556 29.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TON_1443 1be236432e0af0c8c02c91158f4d2011 580 SUPERFAMILY SSF48452 390 549 6.83E-14 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TON_0896 2eab938c31e73d40356c69a98b846c42 289 TIGRFAM TIGR01903 cas5_csm4: CRISPR type III-A/MTUBE-associated RAMP protein Csm4 7 277 2.0E-55 T 23-10-2018 IPR005510 CRISPR type III-associated RAMP protein Csm4 TON_0714 e91ad03a56f2e40591bf9890feee58be 479 SUPERFAMILY SSF103365 2 479 9.29E-185 T 23-10-2018 IPR036025 tRNA-splicing ligase RtcB-like superfamily GO:0006396|GO:0008452 Reactome: R-HSA-6784531 TON_0714 e91ad03a56f2e40591bf9890feee58be 479 Gene3D G3DSA:3.90.1860.10 1 479 8.5E-227 T 23-10-2018 IPR036025 tRNA-splicing ligase RtcB-like superfamily GO:0006396|GO:0008452 Reactome: R-HSA-6784531 TON_0714 e91ad03a56f2e40591bf9890feee58be 479 Pfam PF01139 tRNA-splicing ligase RtcB 45 479 3.7E-180 T 23-10-2018 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 TON_0374 abf754700644f0ca6d8285cd4294e3c4 226 Gene3D G3DSA:3.40.1350.70 1 99 9.1E-49 T 23-10-2018 IPR038230 TBP-interacting protein, N-terminal superfamily TON_0374 abf754700644f0ca6d8285cd4294e3c4 226 Pfam PF15517 TBP-interacting protein N-terminus 3 101 1.4E-46 T 23-10-2018 IPR029125 TBP-interacting protein, N-terminal TON_0374 abf754700644f0ca6d8285cd4294e3c4 226 SUPERFAMILY SSF159612 2 218 1.44E-116 T 23-10-2018 TON_0374 abf754700644f0ca6d8285cd4294e3c4 226 Gene3D G3DSA:3.90.79.30 100 219 3.0E-61 T 23-10-2018 TON_0083 54124309c389a6cf8a9cbe0c5edb0667 126 Hamap MF_00810 50S ribosomal protein L32e [rpl32e]. 2 126 31.47 T 23-10-2018 IPR023654 Ribosomal protein L32e, archaeal GO:0003735|GO:0005840|GO:0006412 TON_0083 54124309c389a6cf8a9cbe0c5edb0667 126 ProSitePatterns PS00580 Ribosomal protein L32e signature. 21 43 - T 23-10-2018 IPR018263 Ribosomal protein L32e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0083 54124309c389a6cf8a9cbe0c5edb0667 126 ProDom PD003823 RIBOSOMAL L32 RIBONUCLEOPROTEIN 60S L32E 50S L32 STRAIN CHROMOSOME DIRECT 21 126 7.0E-53 T 23-10-2018 IPR001515 Ribosomal protein L32e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0083 54124309c389a6cf8a9cbe0c5edb0667 126 SUPERFAMILY SSF52042 5 126 1.44E-45 T 23-10-2018 IPR036351 Ribosomal protein L32e superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0083 54124309c389a6cf8a9cbe0c5edb0667 126 SMART SM01393 18 125 5.1E-61 T 23-10-2018 IPR001515 Ribosomal protein L32e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0083 54124309c389a6cf8a9cbe0c5edb0667 126 Pfam PF01655 Ribosomal protein L32 18 125 2.0E-40 T 23-10-2018 IPR001515 Ribosomal protein L32e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0718 d0b35dc50afd92f781e7c83e43d17755 285 Gene3D G3DSA:3.20.20.60 2 273 1.4E-110 T 23-10-2018 TON_0718 d0b35dc50afd92f781e7c83e43d17755 285 PIRSF PIRSF000388 1 265 8.2E-104 T 23-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 TON_0718 d0b35dc50afd92f781e7c83e43d17755 285 Pfam PF02548 Ketopantoate hydroxymethyltransferase 4 257 1.8E-106 T 23-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 TON_0718 d0b35dc50afd92f781e7c83e43d17755 285 SUPERFAMILY SSF51621 4 262 2.9E-102 T 23-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 TON_0718 d0b35dc50afd92f781e7c83e43d17755 285 Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. 4 262 41.204 T 23-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 TON_0718 d0b35dc50afd92f781e7c83e43d17755 285 TIGRFAM TIGR00222 panB: 3-methyl-2-oxobutanoate hydroxymethyltransferase 7 262 6.3E-89 T 23-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 TON_0819 fcc8848f47eae426b23f0f2260de2c85 250 Pfam PF02146 Sir2 family 20 198 2.0E-58 T 23-10-2018 IPR003000 Sirtuin family GO:0070403 TON_0819 fcc8848f47eae426b23f0f2260de2c85 250 Hamap MF_01121 NAD-dependent protein deacylase [cobB]. 13 248 61.258 T 23-10-2018 IPR027546 Sirtuin, class III GO:0036054|GO:0036055|GO:0070403 Reactome: R-HSA-2151201 TON_0819 fcc8848f47eae426b23f0f2260de2c85 250 Gene3D G3DSA:3.30.1600.10 29 168 3.6E-91 T 23-10-2018 IPR026591 Sirtuin, catalytic core small domain superfamily TON_0819 fcc8848f47eae426b23f0f2260de2c85 250 SUPERFAMILY SSF52467 2 246 4.91E-90 T 23-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily TON_0819 fcc8848f47eae426b23f0f2260de2c85 250 Gene3D G3DSA:3.40.50.1220 12 242 3.6E-91 T 23-10-2018 TON_0458 ad1562805d29640c5104766a613359c5 253 Hamap MF_00917 7-carboxy-7-deazaguanine synthase [queE]. 3 253 38.096 T 23-10-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 TON_0458 ad1562805d29640c5104766a613359c5 253 Gene3D G3DSA:3.20.20.70 4 253 3.8E-26 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TON_0458 ad1562805d29640c5104766a613359c5 253 SUPERFAMILY SSF102114 32 208 3.66E-12 T 23-10-2018 TON_0458 ad1562805d29640c5104766a613359c5 253 Pfam PF13394 4Fe-4S single cluster domain 29 120 8.5E-7 T 23-10-2018 TON_0458 ad1562805d29640c5104766a613359c5 253 Pfam PF04055 Radical SAM superfamily 31 196 1.3E-13 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TON_0806 993d830b2d0dee8f776b334692d65486 202 Gene3D G3DSA:3.90.1720.10 41 200 3.7E-15 T 23-10-2018 TON_0806 993d830b2d0dee8f776b334692d65486 202 SUPERFAMILY SSF54001 43 199 1.47E-26 T 23-10-2018 IPR038765 Papain-like cysteine peptidase superfamily TON_0806 993d830b2d0dee8f776b334692d65486 202 Pfam PF05708 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family 43 198 2.0E-30 T 23-10-2018 IPR024453 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family TON_0806 993d830b2d0dee8f776b334692d65486 202 ProDom PD011073 ORF G6R 56R G6 RPXV073 FPV119 SPV053 ORF8R CPXV094 MPXV-COP-070 43 161 0.002 T 23-10-2018 IPR008548 Poxvirus G6 TON_0860 985cdd97b0ad91b04a5ebf0a3809fe16 570 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 16 177 4.2E-28 T 23-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 TON_0860 985cdd97b0ad91b04a5ebf0a3809fe16 570 SUPERFAMILY SSF52922 464 567 2.62E-13 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TON_0860 985cdd97b0ad91b04a5ebf0a3809fe16 570 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 213 444 8.9E-59 T 23-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 TON_0860 985cdd97b0ad91b04a5ebf0a3809fe16 570 Gene3D G3DSA:3.40.50.970 188 388 3.2E-73 T 23-10-2018 TON_0860 985cdd97b0ad91b04a5ebf0a3809fe16 570 SUPERFAMILY SSF53323 8 222 1.31E-35 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 TON_0860 985cdd97b0ad91b04a5ebf0a3809fe16 570 TIGRFAM TIGR03710 OAFO_sf: 2-oxoacid:acceptor oxidoreductase, alpha subunit 7 563 1.3E-202 T 23-10-2018 IPR022367 2-oxoacid:acceptor oxidoreductase, alpha subunit KEGG: 00020+1.2.7.3|KEGG: 00720+1.2.7.3|MetaCyc: PWY-5392|MetaCyc: PWY-6969 TON_0860 985cdd97b0ad91b04a5ebf0a3809fe16 570 SUPERFAMILY SSF52518 201 449 4.17E-68 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold TON_0860 985cdd97b0ad91b04a5ebf0a3809fe16 570 Gene3D G3DSA:3.40.920.10 5 187 7.2E-24 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 TON_0860 985cdd97b0ad91b04a5ebf0a3809fe16 570 Gene3D G3DSA:3.40.50.920 459 570 1.4E-25 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TON_0197 e9ab8db637cd8697078e056c459b1cbd 289 SUPERFAMILY SSF53474 14 287 3.03E-51 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold TON_0197 e9ab8db637cd8697078e056c459b1cbd 289 Gene3D G3DSA:3.40.50.1820 43 289 3.5E-42 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold TON_0197 e9ab8db637cd8697078e056c459b1cbd 289 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 80 180 3.9E-12 T 23-10-2018 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 TON_1906 9024f614b97cab605eed41460357f96c 194 Pfam PF05175 Methyltransferase small domain 23 165 9.7E-19 T 23-10-2018 IPR007848 Methyltransferase small domain GO:0008168 TON_1906 9024f614b97cab605eed41460357f96c 194 Gene3D G3DSA:3.40.50.150 1 182 1.1E-40 T 23-10-2018 TON_1906 9024f614b97cab605eed41460357f96c 194 TIGRFAM TIGR00537 hemK_rel_arch: putative methylase 16 190 4.3E-61 T 23-10-2018 IPR004557 Eukaryotic/archaeal PrmC-related GO:0008276 Reactome: R-HSA-156581|Reactome: R-HSA-72764 TON_1906 9024f614b97cab605eed41460357f96c 194 SUPERFAMILY SSF53335 3 180 2.39E-41 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TON_1360 8f73b7a8f4288da725f6cbad2c6d0340 176 Gene3D G3DSA:3.30.300.130 72 176 5.1E-36 T 23-10-2018 IPR034904 Fe-S cluster assembly domain superfamily TON_1360 8f73b7a8f4288da725f6cbad2c6d0340 176 SUPERFAMILY SSF117916 77 174 6.21E-32 T 23-10-2018 IPR034904 Fe-S cluster assembly domain superfamily TON_1360 8f73b7a8f4288da725f6cbad2c6d0340 176 Pfam PF01883 Iron-sulfur cluster assembly protein 80 153 2.6E-21 T 23-10-2018 IPR002744 MIP18 family-like TON_0713 1f1efee0659f9ad7c829e0761c7ea2c0 156 TIGRFAM TIGR00581 moaC: molybdenum cofactor biosynthesis protein C 4 145 1.1E-53 T 23-10-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TON_0713 1f1efee0659f9ad7c829e0761c7ea2c0 156 Gene3D G3DSA:3.30.70.640 1 156 4.2E-67 T 23-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TON_0713 1f1efee0659f9ad7c829e0761c7ea2c0 156 Hamap MF_01224_A Cyclic pyranopterin monophosphate synthase [moaC]. 9 154 38.898 T 23-10-2018 IPR023047 Probable cyclic pyranopterin monophosphate synthase accessory protein, archaea KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823 TON_0713 1f1efee0659f9ad7c829e0761c7ea2c0 156 Pfam PF01967 MoaC family 14 152 1.9E-50 T 23-10-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TON_0713 1f1efee0659f9ad7c829e0761c7ea2c0 156 SUPERFAMILY SSF55040 12 153 2.22E-49 T 23-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TON_0912 2458f834681f3cf4f0c94895f62237d2 308 SUPERFAMILY SSF51735 1 306 1.69E-99 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TON_0912 2458f834681f3cf4f0c94895f62237d2 308 Gene3D G3DSA:3.40.50.720 8 289 4.2E-107 T 23-10-2018 TON_0912 2458f834681f3cf4f0c94895f62237d2 308 Gene3D G3DSA:3.90.25.10 168 301 4.2E-107 T 23-10-2018 TON_0912 2458f834681f3cf4f0c94895f62237d2 308 Pfam PF01370 NAD dependent epimerase/dehydratase family 6 236 2.0E-62 T 23-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 TON_0437 e300ac3823fbbedb37469f47d4a55680 245 Hamap MF_01408 Flavin-dependent thymidylate synthase [thyX]. 5 219 30.658 T 23-10-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 TON_0437 e300ac3823fbbedb37469f47d4a55680 245 Pfam PF02511 Thymidylate synthase complementing protein 8 198 4.3E-62 T 23-10-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 TON_0437 e300ac3823fbbedb37469f47d4a55680 245 Gene3D G3DSA:3.30.1360.170 1 202 8.9E-63 T 23-10-2018 TON_0437 e300ac3823fbbedb37469f47d4a55680 245 SUPERFAMILY SSF69796 3 198 1.7E-59 T 23-10-2018 IPR036098 Thymidylate synthase ThyX superfamily GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 TON_0437 e300ac3823fbbedb37469f47d4a55680 245 TIGRFAM TIGR02170 thyX: thymidylate synthase, flavin-dependent 6 199 1.1E-52 T 23-10-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 TON_0529 787d96c99c155800bebe196d3cd1927a 635 Pfam PF01078 Magnesium chelatase, subunit ChlI 41 93 1.1E-9 T 23-10-2018 IPR000523 Magnesium chelatase ChlI domain TON_0529 787d96c99c155800bebe196d3cd1927a 635 SUPERFAMILY SSF52540 36 414 2.0E-37 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_0529 787d96c99c155800bebe196d3cd1927a 635 Gene3D G3DSA:3.30.230.10 432 635 2.3E-80 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TON_0529 787d96c99c155800bebe196d3cd1927a 635 SUPERFAMILY SSF54211 440 613 1.25E-44 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TON_0529 787d96c99c155800bebe196d3cd1927a 635 Gene3D G3DSA:1.10.8.60 321 413 1.7E-44 T 23-10-2018 TON_0529 787d96c99c155800bebe196d3cd1927a 635 Gene3D G3DSA:3.40.50.300 20 134 6.9E-32 T 23-10-2018 TON_0529 787d96c99c155800bebe196d3cd1927a 635 Gene3D G3DSA:3.40.50.300 162 320 3.5E-43 T 23-10-2018 TON_0529 787d96c99c155800bebe196d3cd1927a 635 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 434 615 1.9E-36 T 23-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 TON_0529 787d96c99c155800bebe196d3cd1927a 635 TIGRFAM TIGR00764 lon_rel: putative ATP-dependent protease 24 629 0.0 T 23-10-2018 IPR004663 Lon protease, archaeal GO:0004176|GO:0005524|GO:0030163 TON_0529 787d96c99c155800bebe196d3cd1927a 635 SMART SM00382 59 289 3.7E-5 T 23-10-2018 IPR003593 AAA+ ATPase domain TON_0529 787d96c99c155800bebe196d3cd1927a 635 Pfam PF13654 AAA domain 183 411 7.8E-23 T 23-10-2018 TON_0529 787d96c99c155800bebe196d3cd1927a 635 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 517 536 5.7E-29 T 23-10-2018 TON_0529 787d96c99c155800bebe196d3cd1927a 635 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 67 86 5.7E-29 T 23-10-2018 TON_0529 787d96c99c155800bebe196d3cd1927a 635 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 570 588 5.7E-29 T 23-10-2018 TON_0529 787d96c99c155800bebe196d3cd1927a 635 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 440 456 5.7E-29 T 23-10-2018 TON_0529 787d96c99c155800bebe196d3cd1927a 635 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 547 566 5.7E-29 T 23-10-2018 TON_0468 56e66c913a047839c7ba4bd96e3cb425 83 Gene3D G3DSA:1.20.1280.290 1 83 3.3E-10 T 23-10-2018 TON_0468 56e66c913a047839c7ba4bd96e3cb425 83 Pfam PF04193 PQ loop repeat 4 58 8.3E-5 T 23-10-2018 IPR006603 PQ-loop repeat TON_0528 4406d4ef8b0d6084e91cc6045e382fcc 267 ProDom PD033097 PH0063 MJ0596 ARCHAEAL PF2050 4 103 1.0E-27 T 23-10-2018 IPR022620 Protein of unknown function DUF2666 TON_0528 4406d4ef8b0d6084e91cc6045e382fcc 267 ProDom PD033097 PH0063 MJ0596 ARCHAEAL PF2050 138 266 3.0E-46 T 23-10-2018 IPR022620 Protein of unknown function DUF2666 TON_0528 4406d4ef8b0d6084e91cc6045e382fcc 267 Pfam PF10869 Protein of unknown function (DUF2666) 138 266 5.6E-43 T 23-10-2018 IPR022620 Protein of unknown function DUF2666 TON_0528 4406d4ef8b0d6084e91cc6045e382fcc 267 Pfam PF10869 Protein of unknown function (DUF2666) 4 116 5.7E-14 T 23-10-2018 IPR022620 Protein of unknown function DUF2666 TON_0711 015443e95a73c1a1e10e0946d327f783 576 SMART SM00534 386 574 1.1E-22 T 23-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 TON_0711 015443e95a73c1a1e10e0946d327f783 576 SUPERFAMILY SSF52540 373 553 1.67E-17 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_0711 015443e95a73c1a1e10e0946d327f783 576 PIRSF PIRSF029254 1 575 1.0E-193 T 23-10-2018 IPR012401 DNA-binding protein MutS2, archaea TON_0711 015443e95a73c1a1e10e0946d327f783 576 Pfam PF00488 MutS domain V 389 470 1.7E-6 T 23-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 TON_0711 015443e95a73c1a1e10e0946d327f783 576 Gene3D G3DSA:3.40.50.300 338 526 1.4E-19 T 23-10-2018 TON_0711 015443e95a73c1a1e10e0946d327f783 576 Hamap MF_00971 DNA-binding protein MutS2 [mutS2]. 3 573 25.107 T 23-10-2018 IPR012401 DNA-binding protein MutS2, archaea TON_0087 2df38fbc403a324c1274ff34e6579f63 155 SUPERFAMILY SSF55129 5 155 1.14E-48 T 23-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily TON_0087 2df38fbc403a324c1274ff34e6579f63 155 Gene3D G3DSA:3.30.1390.20 5 143 5.9E-55 T 23-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily TON_0087 2df38fbc403a324c1274ff34e6579f63 155 ProSitePatterns PS00634 Ribosomal protein L30 signature. 22 54 - T 23-10-2018 IPR018038 Ribosomal protein L30, conserved site TON_0087 2df38fbc403a324c1274ff34e6579f63 155 Pfam PF00327 Ribosomal protein L30p/L7e 6 54 1.6E-14 T 23-10-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain TON_0087 2df38fbc403a324c1274ff34e6579f63 155 TIGRFAM TIGR01309 uL30_arch: ribosomal protein uL30 4 155 9.1E-63 T 23-10-2018 IPR005997 Ribosomal protein L30, archaeal GO:0003735|GO:0006412|GO:0015934 TON_0087 2df38fbc403a324c1274ff34e6579f63 155 Hamap MF_01371_A 50S ribosomal protein L30 [rpmD]. 1 155 81.197 T 23-10-2018 IPR005997 Ribosomal protein L30, archaeal GO:0003735|GO:0006412|GO:0015934 TON_0087 2df38fbc403a324c1274ff34e6579f63 155 Gene3D G3DSA:1.10.15.30 60 114 5.9E-55 T 23-10-2018 IPR023106 Ribosomal protein L30, central domain, archaeal type TON_0504 6e8822ad5ac5dc02a8c8304339caf97d 92 SUPERFAMILY SSF82649 4 86 2.46E-11 T 23-10-2018 TON_0504 6e8822ad5ac5dc02a8c8304339caf97d 92 Gene3D G3DSA:3.30.390.50 1 88 4.6E-27 T 23-10-2018 TON_0504 6e8822ad5ac5dc02a8c8304339caf97d 92 Pfam PF10437 Bacterial lipoate protein ligase C-terminus 7 63 2.7E-8 T 23-10-2018 IPR019491 Lipoate protein ligase, C-terminal KEGG: 00785+6.3.1.20 TON_1220 3daf6204be7eae4cbd569ae64c692ee5 427 Gene3D G3DSA:1.25.40.10 260 408 8.9E-10 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TON_1220 3daf6204be7eae4cbd569ae64c692ee5 427 Gene3D G3DSA:1.25.40.10 2 218 5.7E-9 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TON_0901 08f61b5238086fead7a228064a2b2450 424 Pfam PF00375 Sodium:dicarboxylate symporter family 15 412 7.6E-129 T 23-10-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 TON_0901 08f61b5238086fead7a228064a2b2450 424 ProSitePatterns PS00713 Sodium:dicarboxylate symporter family signature 1. 41 56 - T 23-10-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site TON_0901 08f61b5238086fead7a228064a2b2450 424 Gene3D G3DSA:1.10.3860.10 2 424 2.1E-165 T 23-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 TON_0901 08f61b5238086fead7a228064a2b2450 424 SUPERFAMILY SSF118215 16 414 2.62E-123 T 23-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 TON_0901 08f61b5238086fead7a228064a2b2450 424 PRINTS PR00173 Glutamate-aspartate symporter signature 49 69 2.7E-45 T 23-10-2018 TON_0901 08f61b5238086fead7a228064a2b2450 424 PRINTS PR00173 Glutamate-aspartate symporter signature 8 28 2.7E-45 T 23-10-2018 TON_0901 08f61b5238086fead7a228064a2b2450 424 PRINTS PR00173 Glutamate-aspartate symporter signature 78 103 2.7E-45 T 23-10-2018 TON_0901 08f61b5238086fead7a228064a2b2450 424 PRINTS PR00173 Glutamate-aspartate symporter signature 298 324 2.7E-45 T 23-10-2018 TON_0901 08f61b5238086fead7a228064a2b2450 424 PRINTS PR00173 Glutamate-aspartate symporter signature 333 352 2.7E-45 T 23-10-2018 TON_0901 08f61b5238086fead7a228064a2b2450 424 PRINTS PR00173 Glutamate-aspartate symporter signature 360 380 2.7E-45 T 23-10-2018 TON_0901 08f61b5238086fead7a228064a2b2450 424 PRINTS PR00173 Glutamate-aspartate symporter signature 197 216 2.7E-45 T 23-10-2018 TON_1820 39dbe8b97e3eebb70c340154b9e6cf6b 784 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 97 249 2.3E-6 T 23-10-2018 IPR038731 Glycosyltransferase RgtA/B/C/D-like TON_1820 39dbe8b97e3eebb70c340154b9e6cf6b 784 Gene3D G3DSA:3.40.50.12610 483 609 2.4E-10 T 23-10-2018 TON_1478 5b732b86c400e655a94e247589164a3d 395 SUPERFAMILY SSF52518 7 253 6.54E-70 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold TON_1478 5b732b86c400e655a94e247589164a3d 395 Gene3D G3DSA:3.40.50.920 255 395 2.4E-44 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TON_1478 5b732b86c400e655a94e247589164a3d 395 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 265 368 3.7E-33 T 23-10-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II TON_1478 5b732b86c400e655a94e247589164a3d 395 Gene3D G3DSA:3.40.50.970 6 254 2.4E-99 T 23-10-2018 TON_1478 5b732b86c400e655a94e247589164a3d 395 SUPERFAMILY SSF52922 256 377 1.96E-35 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TON_1478 5b732b86c400e655a94e247589164a3d 395 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 19 242 2.3E-79 T 23-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 TON_1106 4e79063500b5a2856bf1e0a9d22ae7ea 77 Gene3D G3DSA:3.10.20.10 3 76 3.0E-28 T 23-10-2018 TON_1106 4e79063500b5a2856bf1e0a9d22ae7ea 77 Pfam PF01775 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A 2 58 1.0E-11 T 23-10-2018 IPR023573 Ribosomal protein 50S-L18Ae/60S-L20/60S-L18A GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_1106 4e79063500b5a2856bf1e0a9d22ae7ea 77 Hamap MF_00273 50S ribosomal protein L18Ae [rpl18a]. 3 58 20.238 T 23-10-2018 IPR028877 50S ribosomal protein L18Ae/60S ribosomal protein L20 and L18a Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_1106 4e79063500b5a2856bf1e0a9d22ae7ea 77 SUPERFAMILY SSF160374 1 73 1.18E-24 T 23-10-2018 TON_1106 4e79063500b5a2856bf1e0a9d22ae7ea 77 ProDom PD010302 RIBOSOMAL LX 50S RIBONUCLEOPROTEIN HL32 DIRECT SEQUENCING LXA LSU 6 51 2.0E-18 T 23-10-2018 IPR002768 50S ribosomal protein L18Ae, archaea GO:0003735|GO:0005840|GO:0006412 TON_0313 f9343397fe4aa98abd37b28f7773d1f9 474 PIRSF PIRSF006603 3 473 1.8E-151 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 TON_0313 f9343397fe4aa98abd37b28f7773d1f9 474 TIGRFAM TIGR00797 matE: MATE efflux family protein 28 427 3.8E-78 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 TON_0313 f9343397fe4aa98abd37b28f7773d1f9 474 Pfam PF01554 MatE 28 188 3.1E-32 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 TON_0313 f9343397fe4aa98abd37b28f7773d1f9 474 Pfam PF01554 MatE 253 414 4.4E-28 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 TON_1808 5f37a20b5c38c16da73a213461d8d5d8 73 Gene3D G3DSA:3.10.20.30 2 73 3.3E-11 T 23-10-2018 IPR012675 Beta-grasp domain superfamily TON_1808 5f37a20b5c38c16da73a213461d8d5d8 73 Pfam PF02597 ThiS family 16 73 8.1E-12 T 23-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 TON_1808 5f37a20b5c38c16da73a213461d8d5d8 73 SUPERFAMILY SSF54285 18 73 1.0E-11 T 23-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp TON_1506 891358076d871e78bd46efd08ffba356 766 Gene3D G3DSA:3.30.420.10 528 766 3.3E-47 T 23-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 TON_1506 891358076d871e78bd46efd08ffba356 766 Pfam PF02171 Piwi domain 466 745 2.6E-12 T 23-10-2018 IPR003165 Piwi domain GO:0003676 TON_1506 891358076d871e78bd46efd08ffba356 766 SUPERFAMILY SSF53098 294 766 1.9E-28 T 23-10-2018 IPR012337 Ribonuclease H-like superfamily TON_1506 891358076d871e78bd46efd08ffba356 766 SMART SM00950 463 751 4.9E-4 T 23-10-2018 IPR003165 Piwi domain GO:0003676 TON_1233 2182d9232c541a63f3dea36f24b50fec 192 PIRSF PIRSF035805 3 192 6.7E-65 T 23-10-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 TON_1233 2182d9232c541a63f3dea36f24b50fec 192 Pfam PF00265 Thymidine kinase 6 189 1.0E-51 T 23-10-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 TON_1233 2182d9232c541a63f3dea36f24b50fec 192 Gene3D G3DSA:3.30.60.20 144 192 2.8E-24 T 23-10-2018 TON_1233 2182d9232c541a63f3dea36f24b50fec 192 ProSitePatterns PS00603 Thymidine kinase cellular-type signature. 176 189 - T 23-10-2018 IPR020633 Thymidine kinase, conserved site GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 TON_1233 2182d9232c541a63f3dea36f24b50fec 192 Hamap MF_00124 Thymidine kinase [tdk]. 4 192 35.97 T 23-10-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 TON_1233 2182d9232c541a63f3dea36f24b50fec 192 Gene3D G3DSA:3.40.50.300 1 142 1.8E-46 T 23-10-2018 TON_1233 2182d9232c541a63f3dea36f24b50fec 192 SUPERFAMILY SSF57716 144 191 1.62E-15 T 23-10-2018 TON_1233 2182d9232c541a63f3dea36f24b50fec 192 SUPERFAMILY SSF52540 5 143 1.06E-38 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_0932 9aff42ebf058ade5a532d153b1cc3782 181 SMART SM00116 14 61 1.2E-8 T 23-10-2018 IPR000644 CBS domain TON_0932 9aff42ebf058ade5a532d153b1cc3782 181 SMART SM00116 79 126 2.3E-8 T 23-10-2018 IPR000644 CBS domain TON_0932 9aff42ebf058ade5a532d153b1cc3782 181 Gene3D G3DSA:3.10.580.10 3 179 1.3E-40 T 23-10-2018 TON_0932 9aff42ebf058ade5a532d153b1cc3782 181 Pfam PF00571 CBS domain 72 125 7.2E-11 T 23-10-2018 IPR000644 CBS domain TON_0932 9aff42ebf058ade5a532d153b1cc3782 181 Pfam PF00571 CBS domain 7 60 2.6E-11 T 23-10-2018 IPR000644 CBS domain TON_0932 9aff42ebf058ade5a532d153b1cc3782 181 SUPERFAMILY SSF54631 5 127 1.01E-30 T 23-10-2018 TON_0641 1c937a0cd769993a401a653763b797a7 94 SMART SM01152 7 82 1.7E-34 T 23-10-2018 IPR003746 Protein of unknown function DUF167 TON_0641 1c937a0cd769993a401a653763b797a7 94 SUPERFAMILY SSF69786 2 92 1.83E-29 T 23-10-2018 IPR036591 YggU-like superfamily TON_0641 1c937a0cd769993a401a653763b797a7 94 Pfam PF02594 Uncharacterised ACR, YggU family COG1872 11 80 3.9E-24 T 23-10-2018 IPR003746 Protein of unknown function DUF167 TON_0641 1c937a0cd769993a401a653763b797a7 94 Hamap MF_00634 UPF0235 protein YggU [yggU]. 7 94 21.059 T 23-10-2018 IPR003746 Protein of unknown function DUF167 TON_0641 1c937a0cd769993a401a653763b797a7 94 Gene3D G3DSA:3.30.1200.10 1 94 2.6E-33 T 23-10-2018 IPR036591 YggU-like superfamily TON_0641 1c937a0cd769993a401a653763b797a7 94 TIGRFAM TIGR00251 TIGR00251: TIGR00251 family protein 4 88 8.1E-30 T 23-10-2018 IPR005228 Conserved hypothetical protein CHP00251 TON_1559 ebb2619c96953da3dbe911728959b11a 392 SUPERFAMILY SSF56762 3 386 2.35E-74 T 23-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_1559 ebb2619c96953da3dbe911728959b11a 392 Pfam PF00374 Nickel-dependent hydrogenase 39 109 7.0E-14 T 23-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 TON_1559 ebb2619c96953da3dbe911728959b11a 392 ProSitePatterns PS00507 Nickel-dependent hydrogenases large subunit signature 1. 39 64 - T 23-10-2018 IPR018194 Nickel-dependent hydrogenase, large subunit, nickel binding site GO:0008901|GO:0016151|GO:0055114 TON_1559 ebb2619c96953da3dbe911728959b11a 392 Gene3D G3DSA:1.10.645.10 1 386 5.5E-91 T 23-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_1148 895e48ddb0d94a7feefe775788ddb12f 256 Pfam PF09968 Uncharacterized protein domain (DUF2202) 86 247 1.4E-65 T 23-10-2018 IPR019243 Domain of unknown function DUF2202 TON_1148 895e48ddb0d94a7feefe775788ddb12f 256 SUPERFAMILY SSF47240 85 225 2.37E-14 T 23-10-2018 IPR009078 Ferritin-like superfamily TON_1148 895e48ddb0d94a7feefe775788ddb12f 256 Gene3D G3DSA:1.20.1260.10 81 255 1.9E-72 T 23-10-2018 IPR012347 Ferritin-like TON_0338 37f3a47b51cc9a7e41c3cf2f6e6afd14 214 ProSitePatterns PS01228 Hypothetical cof family signature 1. 3 14 - T 23-10-2018 TON_0338 37f3a47b51cc9a7e41c3cf2f6e6afd14 214 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 76 186 1.7E-12 T 23-10-2018 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 TON_0338 37f3a47b51cc9a7e41c3cf2f6e6afd14 214 Gene3D G3DSA:1.10.150.520 15 86 9.4E-50 T 23-10-2018 TON_0338 37f3a47b51cc9a7e41c3cf2f6e6afd14 214 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 99 179 1.8E-13 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TON_0338 37f3a47b51cc9a7e41c3cf2f6e6afd14 214 Pfam PF13419 Haloacid dehalogenase-like hydrolase 4 185 1.5E-31 T 23-10-2018 TON_0338 37f3a47b51cc9a7e41c3cf2f6e6afd14 214 Gene3D G3DSA:3.40.50.1000 2 206 9.4E-50 T 23-10-2018 IPR023214 HAD superfamily TON_0338 37f3a47b51cc9a7e41c3cf2f6e6afd14 214 SUPERFAMILY SSF56784 1 211 1.17E-50 T 23-10-2018 IPR036412 HAD-like superfamily TON_0338 37f3a47b51cc9a7e41c3cf2f6e6afd14 214 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 1 12 1.2E-16 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TON_0338 37f3a47b51cc9a7e41c3cf2f6e6afd14 214 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 174 187 1.2E-16 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TON_0338 37f3a47b51cc9a7e41c3cf2f6e6afd14 214 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 98 111 1.2E-16 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TON_0338 37f3a47b51cc9a7e41c3cf2f6e6afd14 214 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 128 144 1.2E-16 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TON_0338 37f3a47b51cc9a7e41c3cf2f6e6afd14 214 TIGRFAM TIGR02253 CTE7: HAD hydrolase, TIGR02253 family 2 206 2.4E-54 T 23-10-2018 IPR011950 HAD-superfamily hydrolase, subfamily IA, CTE7 GO:0016787 Reactome: R-HSA-4085001 TON_0338 37f3a47b51cc9a7e41c3cf2f6e6afd14 214 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 75 185 1.1E-13 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TON_0522 188af20e1163b7ef4b8a3338443e3aaf 237 Pfam PF01940 Integral membrane protein DUF92 12 215 1.2E-51 T 23-10-2018 IPR002794 Protein of unknown function DUF92, TMEM19 GO:0016021 TON_1527 1875a3abae1e865b58e45221091c825d 185 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 8 180 1.5E-45 T 23-10-2018 IPR001303 Class II aldolase/adducin N-terminal TON_1527 1875a3abae1e865b58e45221091c825d 185 SUPERFAMILY SSF53639 5 183 9.42E-52 T 23-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily TON_1527 1875a3abae1e865b58e45221091c825d 185 Gene3D G3DSA:3.40.225.10 3 185 1.0E-57 T 23-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily TON_1527 1875a3abae1e865b58e45221091c825d 185 SMART SM01007 7 181 7.8E-55 T 23-10-2018 IPR001303 Class II aldolase/adducin N-terminal TON_1576 b6249ddcf1b9f70182f82156c631d749 84 Pfam PF13244 Domain of unknown function (DUF4040) 16 80 1.1E-11 T 23-10-2018 IPR025383 Domain of unknown function DUF4040 TON_1042 7d8f57c79a07f376e350089606aa49e1 403 SUPERFAMILY SSF52540 70 353 2.19E-75 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_1042 7d8f57c79a07f376e350089606aa49e1 403 Pfam PF00271 Helicase conserved C-terminal domain 229 333 5.2E-26 T 23-10-2018 IPR001650 Helicase, C-terminal TON_1042 7d8f57c79a07f376e350089606aa49e1 403 Gene3D G3DSA:3.40.50.300 1 207 6.0E-78 T 23-10-2018 TON_1042 7d8f57c79a07f376e350089606aa49e1 403 Gene3D G3DSA:3.40.50.300 214 397 9.6E-52 T 23-10-2018 TON_1042 7d8f57c79a07f376e350089606aa49e1 403 SMART SM00490 252 333 1.9E-32 T 23-10-2018 IPR001650 Helicase, C-terminal TON_1042 7d8f57c79a07f376e350089606aa49e1 403 SMART SM00487 20 223 2.6E-66 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TON_1042 7d8f57c79a07f376e350089606aa49e1 403 Pfam PF00270 DEAD/DEAH box helicase 25 189 1.4E-49 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 TON_1042 7d8f57c79a07f376e350089606aa49e1 403 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 149 157 - T 23-10-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site TON_1837 b670436ebfe2994b872b85439abe1971 340 Gene3D G3DSA:2.160.10.10 248 339 2.8E-7 T 23-10-2018 TON_1837 b670436ebfe2994b872b85439abe1971 340 Gene3D G3DSA:3.90.550.10 6 247 7.7E-56 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TON_1837 b670436ebfe2994b872b85439abe1971 340 SUPERFAMILY SSF53448 9 287 4.96E-55 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TON_1837 b670436ebfe2994b872b85439abe1971 340 Pfam PF00483 Nucleotidyl transferase 12 242 4.6E-39 T 23-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 TON_1837 b670436ebfe2994b872b85439abe1971 340 SUPERFAMILY SSF51161 249 320 1.12E-9 T 23-10-2018 IPR011004 Trimeric LpxA-like superfamily TON_0421 654c96cb893e7e4cbcf3341fa7587c1f 421 SUPERFAMILY SSF89550 7 229 2.55E-15 T 23-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 TON_0421 654c96cb893e7e4cbcf3341fa7587c1f 421 Gene3D G3DSA:3.20.20.140 4 235 1.2E-16 T 23-10-2018 TON_0421 654c96cb893e7e4cbcf3341fa7587c1f 421 Pfam PF13263 PHP-associated 177 227 2.3E-5 T 23-10-2018 TON_0421 654c96cb893e7e4cbcf3341fa7587c1f 421 TIGRFAM TIGR00375 TIGR00375: TIGR00375 family protein 8 382 1.9E-126 T 23-10-2018 IPR005287 Conserved hypothetical protein CHP00375 TON_1095 170cf490483b15238e8b32e2e028799a 105 SUPERFAMILY SSF50346 4 79 1.07E-12 T 23-10-2018 IPR011033 PRC-barrel-like superfamily TON_1095 170cf490483b15238e8b32e2e028799a 105 Gene3D G3DSA:2.30.30.240 4 81 2.1E-5 T 23-10-2018 TON_1095 170cf490483b15238e8b32e2e028799a 105 Pfam PF05239 PRC-barrel domain 3 82 1.3E-13 T 23-10-2018 IPR027275 PRC-barrel domain TON_1344 1f7ffdeda9a54363bddc08a5eefe70dc 185 Pfam PF13207 AAA domain 6 137 3.1E-21 T 23-10-2018 TON_1344 1f7ffdeda9a54363bddc08a5eefe70dc 185 Gene3D G3DSA:3.40.50.300 1 183 8.6E-46 T 23-10-2018 TON_1344 1f7ffdeda9a54363bddc08a5eefe70dc 185 SUPERFAMILY SSF52540 1 182 3.8E-20 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_1344 1f7ffdeda9a54363bddc08a5eefe70dc 185 Hamap MF_01111 UPF0200 protein . 2 182 32.488 T 23-10-2018 IPR022970 Nucleoside triphosphate hydrolase-related TON_1228 2c1dd8c905084159783cf3ec3f430dd4 439 Gene3D G3DSA:3.40.50.10180 26 271 1.4E-163 T 23-10-2018 IPR038614 Glycerate kinase, N-terminal domain superfamily Reactome: R-HSA-70350 TON_1228 2c1dd8c905084159783cf3ec3f430dd4 439 SUPERFAMILY SSF82544 5 438 1.83E-133 T 23-10-2018 TON_1228 2c1dd8c905084159783cf3ec3f430dd4 439 Pfam PF13660 Domain of unknown function (DUF4147) 12 247 1.1E-81 T 23-10-2018 IPR025286 MOFRL-associated domain Reactome: R-HSA-70350 TON_1228 2c1dd8c905084159783cf3ec3f430dd4 439 Gene3D G3DSA:3.40.1480.10 272 435 1.4E-163 T 23-10-2018 IPR037035 Glycerate kinase-like, C-terminal domain superfamily TON_1228 2c1dd8c905084159783cf3ec3f430dd4 439 Pfam PF05161 MOFRL family 328 431 6.1E-33 T 23-10-2018 IPR007835 MOFRL domain Reactome: R-HSA-70350 TON_1956 71615ecccb57a4598d4dd3b5e94b9f8c 144 SUPERFAMILY SSF46785 4 63 1.98E-16 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TON_1956 71615ecccb57a4598d4dd3b5e94b9f8c 144 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 64 129 3.5E-21 T 23-10-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 TON_1956 71615ecccb57a4598d4dd3b5e94b9f8c 144 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 3 58 3.4E-18 T 23-10-2018 IPR022687 DTXR-type HTH domain GO:0003677 TON_1956 71615ecccb57a4598d4dd3b5e94b9f8c 144 SUPERFAMILY SSF47979 64 137 3.66E-18 T 23-10-2018 IPR036421 Iron dependent repressor, metal binding and dimerisation domain superfamily GO:0046914|GO:0046983 TON_1956 71615ecccb57a4598d4dd3b5e94b9f8c 144 SMART SM00529 25 124 2.6E-42 T 23-10-2018 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 TON_1956 71615ecccb57a4598d4dd3b5e94b9f8c 144 Gene3D G3DSA:1.10.60.10 69 123 2.5E-20 T 23-10-2018 IPR036421 Iron dependent repressor, metal binding and dimerisation domain superfamily GO:0046914|GO:0046983 TON_1956 71615ecccb57a4598d4dd3b5e94b9f8c 144 Gene3D G3DSA:1.10.10.10 3 68 1.6E-25 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TON_0651 c840a686fe832c62b311b5af504bb38f 348 Pfam PF01321 Creatinase/Prolidase N-terminal domain 2 124 4.2E-23 T 23-10-2018 IPR000587 Creatinase, N-terminal GO:0016787 TON_0651 c840a686fe832c62b311b5af504bb38f 348 SUPERFAMILY SSF55920 123 347 7.07E-85 T 23-10-2018 IPR036005 Creatinase/aminopeptidase-like TON_0651 c840a686fe832c62b311b5af504bb38f 348 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 280 292 - T 23-10-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site TON_0651 c840a686fe832c62b311b5af504bb38f 348 SUPERFAMILY SSF53092 6 124 1.67E-25 T 23-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal TON_0651 c840a686fe832c62b311b5af504bb38f 348 Pfam PF00557 Metallopeptidase family M24 133 334 2.3E-70 T 23-10-2018 IPR000994 Peptidase M24 TON_0651 c840a686fe832c62b311b5af504bb38f 348 Gene3D G3DSA:3.90.230.10 123 348 3.4E-90 T 23-10-2018 TON_0651 c840a686fe832c62b311b5af504bb38f 348 Gene3D G3DSA:3.40.350.10 1 122 2.0E-29 T 23-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal TON_0736 acb9f04f79bf144c0c78bde969f90bfd 330 SUPERFAMILY SSF55326 26 140 5.76E-25 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily TON_0736 acb9f04f79bf144c0c78bde969f90bfd 330 Pfam PF00586 AIR synthase related protein, N-terminal domain 40 140 9.3E-17 T 23-10-2018 IPR016188 PurM-like, N-terminal domain TON_0736 acb9f04f79bf144c0c78bde969f90bfd 330 Gene3D G3DSA:3.30.1330.10 10 144 2.0E-29 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily TON_0736 acb9f04f79bf144c0c78bde969f90bfd 330 PIRSF PIRSF005644 2 330 3.9E-94 T 23-10-2018 IPR011854 Carbamoyl dehydratase HypE TON_0736 acb9f04f79bf144c0c78bde969f90bfd 330 Gene3D G3DSA:3.90.650.10 146 330 2.4E-53 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily TON_0736 acb9f04f79bf144c0c78bde969f90bfd 330 Pfam PF02769 AIR synthase related protein, C-terminal domain 152 310 1.4E-28 T 23-10-2018 IPR010918 PurM-like, C-terminal domain TON_0736 acb9f04f79bf144c0c78bde969f90bfd 330 SUPERFAMILY SSF56042 146 314 8.52E-37 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily TON_1840 9d6df63b2c0ad297d5a22caadda18fed 134 SUPERFAMILY SSF46785 57 132 2.72E-16 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TON_1840 9d6df63b2c0ad297d5a22caadda18fed 134 Gene3D G3DSA:1.10.10.10 57 133 1.1E-20 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TON_1840 9d6df63b2c0ad297d5a22caadda18fed 134 Gene3D G3DSA:1.10.8.60 1 56 4.5E-13 T 23-10-2018 TON_0476 436548d36ec9798e3036da52c44d2e6d 454 TIGRFAM TIGR01703 hybrid_clust: hydroxylamine reductase 31 437 3.3E-189 T 23-10-2018 IPR010048 Hydroxylamine reductase GO:0005737|GO:0016661|GO:0051536|GO:0055114 KEGG: 00910+1.7.99.1 TON_0476 436548d36ec9798e3036da52c44d2e6d 454 Pfam PF03063 Prismane/CO dehydrogenase family 9 91 2.6E-16 T 23-10-2018 IPR004137 Hydroxylamine reductase/Ni-containing CO dehydrogenase GO:0016491|GO:0055114 KEGG: 00910+1.7.99.1 TON_0476 436548d36ec9798e3036da52c44d2e6d 454 SUPERFAMILY SSF56821 7 437 8.5E-148 T 23-10-2018 IPR011254 Prismane-like superfamily GO:0003824|GO:0016491|GO:0055114 TON_0476 436548d36ec9798e3036da52c44d2e6d 454 Hamap MF_00069 Hydroxylamine reductase [hcp]. 9 438 16.338 T 23-10-2018 IPR010048 Hydroxylamine reductase GO:0005737|GO:0016661|GO:0051536|GO:0055114 KEGG: 00910+1.7.99.1 TON_0476 436548d36ec9798e3036da52c44d2e6d 454 Gene3D G3DSA:3.40.50.2030 269 437 7.2E-60 T 23-10-2018 IPR016099 Prismane-like, alpha/beta-sandwich GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 TON_0476 436548d36ec9798e3036da52c44d2e6d 454 Gene3D G3DSA:3.40.50.2030 121 268 1.2E-54 T 23-10-2018 IPR016099 Prismane-like, alpha/beta-sandwich GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 TON_0476 436548d36ec9798e3036da52c44d2e6d 454 Pfam PF03063 Prismane/CO dehydrogenase family 88 434 4.2E-96 T 23-10-2018 IPR004137 Hydroxylamine reductase/Ni-containing CO dehydrogenase GO:0016491|GO:0055114 KEGG: 00910+1.7.99.1 TON_0476 436548d36ec9798e3036da52c44d2e6d 454 Gene3D G3DSA:1.20.1270.20 30 115 1.4E-27 T 23-10-2018 IPR016100 Prismane, alpha-bundle GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 TON_1463 dd5ac6e614689120ea956ded305e79a6 307 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 108 283 1.3E-71 T 23-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 TON_1463 dd5ac6e614689120ea956ded305e79a6 307 SUPERFAMILY SSF52283 4 136 2.27E-39 T 23-10-2018 TON_1463 dd5ac6e614689120ea956ded305e79a6 307 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 193 215 - T 23-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site TON_1463 dd5ac6e614689120ea956ded305e79a6 307 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 145 172 - T 23-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 TON_1463 dd5ac6e614689120ea956ded305e79a6 307 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 6 306 1.9E-40 T 23-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 TON_1463 dd5ac6e614689120ea956ded305e79a6 307 Gene3D G3DSA:3.40.50.720 95 285 2.7E-134 T 23-10-2018 TON_1463 dd5ac6e614689120ea956ded305e79a6 307 SUPERFAMILY SSF51735 102 283 1.91E-67 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TON_1463 dd5ac6e614689120ea956ded305e79a6 307 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 222 238 - T 23-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site TON_1463 dd5ac6e614689120ea956ded305e79a6 307 Gene3D G3DSA:3.40.50.720 10 301 2.7E-134 T 23-10-2018 TON_1251 eca88d0e603fd184d5bdc0e1d2d9caa8 215 SMART SM00934 8 208 2.8E-60 T 23-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TON_1251 eca88d0e603fd184d5bdc0e1d2d9caa8 215 SUPERFAMILY SSF51366 4 213 1.07E-58 T 23-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 TON_1251 eca88d0e603fd184d5bdc0e1d2d9caa8 215 Hamap MF_01200_A Orotidine 5'-phosphate decarboxylase [pyrF]. 9 214 36.609 T 23-10-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TON_1251 eca88d0e603fd184d5bdc0e1d2d9caa8 215 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 61 74 - T 23-10-2018 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TON_1251 eca88d0e603fd184d5bdc0e1d2d9caa8 215 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 8 207 3.5E-37 T 23-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TON_1251 eca88d0e603fd184d5bdc0e1d2d9caa8 215 TIGRFAM TIGR01740 pyrF: orotidine 5'-phosphate decarboxylase 9 208 2.4E-50 T 23-10-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TON_1251 eca88d0e603fd184d5bdc0e1d2d9caa8 215 Gene3D G3DSA:3.20.20.70 1 214 3.2E-63 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TON_1618 c89ddbcc287d2b076ab5ae5bc9a1cfb9 305 SUPERFAMILY SSF46785 146 202 2.51E-7 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TON_1618 c89ddbcc287d2b076ab5ae5bc9a1cfb9 305 Pfam PF13412 Winged helix-turn-helix DNA-binding 153 197 3.4E-9 T 23-10-2018 TON_1618 c89ddbcc287d2b076ab5ae5bc9a1cfb9 305 Gene3D G3DSA:1.10.10.10 155 201 7.5E-10 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TON_1168 e5d2da74f2d264b91d27d2c94c8d07d5 187 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 68 90 - T 23-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 TON_1168 e5d2da74f2d264b91d27d2c94c8d07d5 187 Gene3D G3DSA:1.20.120.1760 7 187 1.0E-51 T 23-10-2018 TON_1168 e5d2da74f2d264b91d27d2c94c8d07d5 187 Pfam PF01066 CDP-alcohol phosphatidyltransferase 26 90 2.0E-15 T 23-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 TON_1522 e79c97a51e734f5e73e1c4240baf4d1a 482 PIRSF PIRSF016666 1 482 3.1E-238 T 23-10-2018 IPR016675 Uncharacterised conserved protein UCP016666 TON_1522 e79c97a51e734f5e73e1c4240baf4d1a 482 Pfam PF09910 Uncharacterized protein conserved in archaea (DUF2139) 31 356 1.9E-152 T 23-10-2018 IPR016675 Uncharacterised conserved protein UCP016666 TON_1522 e79c97a51e734f5e73e1c4240baf4d1a 482 SUPERFAMILY SSF75011 73 220 9.15E-9 T 23-10-2018 TON_1522 e79c97a51e734f5e73e1c4240baf4d1a 482 Gene3D G3DSA:2.130.10.10 55 258 1.7E-5 T 23-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 TON_1144 df2d98d8e6f306daa95d62c8c05eb170 245 Gene3D G3DSA:1.20.1260.10 68 240 6.0E-74 T 23-10-2018 IPR012347 Ferritin-like TON_1144 df2d98d8e6f306daa95d62c8c05eb170 245 Pfam PF09968 Uncharacterized protein domain (DUF2202) 73 233 1.2E-65 T 23-10-2018 IPR019243 Domain of unknown function DUF2202 TON_1144 df2d98d8e6f306daa95d62c8c05eb170 245 SUPERFAMILY SSF47240 74 212 1.31E-11 T 23-10-2018 IPR009078 Ferritin-like superfamily TON_1852 aea45bc8e52252c1ded76bdeefc245a2 474 Pfam PF01943 Polysaccharide biosynthesis protein 8 276 2.5E-42 T 23-10-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 TON_1852 aea45bc8e52252c1ded76bdeefc245a2 474 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 328 459 1.1E-16 T 23-10-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain TON_1594 59dd22959f0823911949bea10cea5b0b 330 Pfam PF00146 NADH dehydrogenase 17 324 1.1E-60 T 23-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_0555 36e9adda5e0acf64500bb36466a3457d 69 SUPERFAMILY SSF50346 1 66 2.83E-15 T 23-10-2018 IPR011033 PRC-barrel-like superfamily TON_0555 36e9adda5e0acf64500bb36466a3457d 69 Pfam PF05239 PRC-barrel domain 2 68 2.1E-13 T 23-10-2018 IPR027275 PRC-barrel domain TON_0555 36e9adda5e0acf64500bb36466a3457d 69 Gene3D G3DSA:2.30.30.240 3 69 7.6E-8 T 23-10-2018 TON_0885 2391777cfaa719ff61a589ed0cd98f94 208 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 31 103 2.5E-31 T 23-10-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 TON_0885 2391777cfaa719ff61a589ed0cd98f94 208 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 123 206 1.0E-13 T 23-10-2018 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 TON_0885 2391777cfaa719ff61a589ed0cd98f94 208 SUPERFAMILY SSF141734 3 109 4.45E-43 T 23-10-2018 IPR038019 Phosphoribosyl-AMP cyclohydrolase domain superfamily KEGG: 00340+3.5.4.19 TON_0885 2391777cfaa719ff61a589ed0cd98f94 208 Hamap MF_01019 Histidine biosynthesis bifunctional protein HisIE [hisI]. 6 208 35.982 T 23-10-2018 IPR023019 Histidine biosynthesis bifunctional protein HisIE GO:0000105|GO:0004635|GO:0004636 KEGG: 00340+3.6.1.31+3.5.4.19 TON_0885 2391777cfaa719ff61a589ed0cd98f94 208 TIGRFAM TIGR03188 histidine_hisI: phosphoribosyl-ATP diphosphatase 123 203 1.2E-27 T 23-10-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 TON_0885 2391777cfaa719ff61a589ed0cd98f94 208 Hamap MF_01020 Phosphoribosyl-ATP pyrophosphatase [hisE]. 120 203 19.011 T 23-10-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 TON_0885 2391777cfaa719ff61a589ed0cd98f94 208 Gene3D G3DSA:1.10.287.1080 120 208 2.0E-26 T 23-10-2018 TON_0885 2391777cfaa719ff61a589ed0cd98f94 208 Gene3D G3DSA:3.10.20.400 2 94 3.9E-34 T 23-10-2018 IPR038019 Phosphoribosyl-AMP cyclohydrolase domain superfamily KEGG: 00340+3.5.4.19 TON_0885 2391777cfaa719ff61a589ed0cd98f94 208 Hamap MF_01021 Phosphoribosyl-AMP cyclohydrolase [hisI]. 5 107 28.605 T 23-10-2018 IPR026660 Phosphoribosyl-AMP cyclohydrolase GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 TON_0885 2391777cfaa719ff61a589ed0cd98f94 208 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 53 106 2.0E-23 T 23-10-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 TON_0885 2391777cfaa719ff61a589ed0cd98f94 208 SUPERFAMILY SSF101386 122 207 9.16E-23 T 23-10-2018 TON_0250 dc4f4c860abcc292346afc00fc7ab961 61 ProDom PD256538 PF0630 PYRAB06030 AF2407.1 5 61 3.0E-25 T 23-10-2018 IPR020199 Uncharacterised protein family PYRAB06030 TON_0250 dc4f4c860abcc292346afc00fc7ab961 61 Pfam PF14354 Restriction alleviation protein Lar 9 48 1.3E-6 T 23-10-2018 TON_1957 8a3cd4847b5b45e8b1ad94d530751c53 444 Pfam PF00860 Permease family 20 399 2.1E-46 T 23-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 TON_1957 8a3cd4847b5b45e8b1ad94d530751c53 444 PIRSF PIRSF005353 1 441 3.4E-168 T 23-10-2018 IPR026033 Purine permease PbuG-like TON_0158 6025305a9d0850804b1adc76baa3c49a 342 Pfam PF02653 Branched-chain amino acid transport system / permease component 7 316 8.7E-50 T 23-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TON_0722 38ec4e88bd01fe64fb8013a652a44fc1 271 SUPERFAMILY SSF48317 62 223 1.98E-7 T 23-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily TON_0722 38ec4e88bd01fe64fb8013a652a44fc1 271 Gene3D G3DSA:1.20.144.10 141 230 2.0E-6 T 23-10-2018 TON_0722 38ec4e88bd01fe64fb8013a652a44fc1 271 Pfam PF14378 PAP2 superfamily 64 213 3.5E-11 T 23-10-2018 IPR026841 Inositolphosphotransferase Aur1/Ipt1 TON_0487 b20deaae421dd30f285beb0d83ce9df7 391 Gene3D G3DSA:1.10.645.20 27 391 2.7E-112 T 23-10-2018 IPR038290 NADH-quinone oxidoreductase, subunit D superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_0487 b20deaae421dd30f285beb0d83ce9df7 391 ProSitePatterns PS00535 Respiratory chain NADH dehydrogenase 49 Kd subunit signature. 61 72 - T 23-10-2018 IPR014029 NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_0487 b20deaae421dd30f285beb0d83ce9df7 391 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 139 391 3.3E-70 T 23-10-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_0487 b20deaae421dd30f285beb0d83ce9df7 391 SUPERFAMILY SSF56762 38 391 2.22E-91 T 23-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_1683 3d031d8a8bc519839f7785243c389e30 317 Gene3D G3DSA:3.40.50.300 21 187 4.3E-49 T 23-10-2018 TON_1683 3d031d8a8bc519839f7785243c389e30 317 PIRSF PIRSF002849 1 316 3.6E-140 T 23-10-2018 TON_1683 3d031d8a8bc519839f7785243c389e30 317 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 40 170 1.3E-68 T 23-10-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 TON_1683 3d031d8a8bc519839f7785243c389e30 317 Gene3D G3DSA:1.10.8.300 202 311 4.0E-37 T 23-10-2018 TON_1683 3d031d8a8bc519839f7785243c389e30 317 SUPERFAMILY SSF52540 16 287 2.95E-48 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_0983 c3188bfd14b868646f5b3cf54fa22dd8 483 SUPERFAMILY SSF53850 86 321 1.29E-38 T 23-10-2018 TON_0983 c3188bfd14b868646f5b3cf54fa22dd8 483 Pfam PF13416 Bacterial extracellular solute-binding protein 89 320 3.5E-19 T 23-10-2018 IPR006059 Bacterial extracellular solute-binding protein TON_0983 c3188bfd14b868646f5b3cf54fa22dd8 483 Gene3D G3DSA:3.40.190.10 153 272 3.9E-33 T 23-10-2018 TON_0983 c3188bfd14b868646f5b3cf54fa22dd8 483 Gene3D G3DSA:3.40.190.10 87 308 3.9E-33 T 23-10-2018 TON_0649 a0a1628ce34cfa08d29efa81cf153b4d 88 Hamap MF_00573 50S ribosomal protein L35Ae [rpl35ae]. 4 88 23.379 T 23-10-2018 IPR001780 Ribosomal protein L35A GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0649 a0a1628ce34cfa08d29efa81cf153b4d 88 ProDom PD012670 RIBOSOMAL L35A 60S RIBONUCLEOPROTEIN L35A L35AE 50S RNA-BINDING TRNA-BINDING SEQUENCE 5 87 6.0E-31 T 23-10-2018 IPR001780 Ribosomal protein L35A GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0649 a0a1628ce34cfa08d29efa81cf153b4d 88 Pfam PF01247 Ribosomal protein L35Ae 5 87 7.5E-14 T 23-10-2018 IPR001780 Ribosomal protein L35A GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0649 a0a1628ce34cfa08d29efa81cf153b4d 88 SUPERFAMILY SSF50447 5 87 2.03E-22 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily TON_0649 a0a1628ce34cfa08d29efa81cf153b4d 88 Gene3D G3DSA:2.40.10.190 3 88 9.9E-24 T 23-10-2018 IPR038661 Ribosomal protein L35A superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0958 d02d66dab4c32401e8fc86042e5eb37c 318 ProSitePatterns PS01270 Band 7 protein family signature. 135 163 - T 23-10-2018 IPR018080 Band 7/stomatin-like, conserved site TON_0958 d02d66dab4c32401e8fc86042e5eb37c 318 Gene3D G3DSA:3.30.479.30 50 181 7.0E-51 T 23-10-2018 TON_0958 d02d66dab4c32401e8fc86042e5eb37c 318 SUPERFAMILY SSF117892 53 186 4.84E-46 T 23-10-2018 IPR036013 Band 7/SPFH domain superfamily TON_0958 d02d66dab4c32401e8fc86042e5eb37c 318 SMART SM00244 22 179 1.9E-72 T 23-10-2018 IPR001107 Band 7 domain TON_0958 d02d66dab4c32401e8fc86042e5eb37c 318 PRINTS PR00721 Stomatin signature 131 154 1.7E-34 T 23-10-2018 IPR001972 Stomatin family GO:0016020 TON_0958 d02d66dab4c32401e8fc86042e5eb37c 318 PRINTS PR00721 Stomatin signature 155 173 1.7E-34 T 23-10-2018 IPR001972 Stomatin family GO:0016020 TON_0958 d02d66dab4c32401e8fc86042e5eb37c 318 PRINTS PR00721 Stomatin signature 76 97 1.7E-34 T 23-10-2018 IPR001972 Stomatin family GO:0016020 TON_0958 d02d66dab4c32401e8fc86042e5eb37c 318 PRINTS PR00721 Stomatin signature 111 128 1.7E-34 T 23-10-2018 IPR001972 Stomatin family GO:0016020 TON_0958 d02d66dab4c32401e8fc86042e5eb37c 318 PRINTS PR00721 Stomatin signature 29 51 1.7E-34 T 23-10-2018 IPR001972 Stomatin family GO:0016020 TON_0958 d02d66dab4c32401e8fc86042e5eb37c 318 PRINTS PR00721 Stomatin signature 174 195 1.7E-34 T 23-10-2018 IPR001972 Stomatin family GO:0016020 TON_0958 d02d66dab4c32401e8fc86042e5eb37c 318 Pfam PF01145 SPFH domain / Band 7 family 26 195 4.2E-42 T 23-10-2018 IPR001107 Band 7 domain TON_0350 c9266ce8186fc282b3eb1864ed91f880 126 Hamap MF_01223 UPF0212 protein . 1 112 32.377 T 23-10-2018 IPR007564 Uncharacterised protein family UPF0212 TON_0350 c9266ce8186fc282b3eb1864ed91f880 126 Pfam PF04475 Protein of unknown function (DUF555) 3 104 2.9E-40 T 23-10-2018 IPR007564 Uncharacterised protein family UPF0212 TON_0350 c9266ce8186fc282b3eb1864ed91f880 126 PIRSF PIRSF016934 1 122 5.1E-53 T 23-10-2018 IPR007564 Uncharacterised protein family UPF0212 TON_0350 c9266ce8186fc282b3eb1864ed91f880 126 ProDom PD020367 UPF0212 RRNAC1165 RRNAC0441 AF0282 VNG1264C MJ0068 PYRAB08340 PH1312 MA1372 TK1194 1 102 2.0E-51 T 23-10-2018 IPR007564 Uncharacterised protein family UPF0212 TON_1948 1440838a1cc587e0d446599a4e1e0b2a 203 Gene3D G3DSA:3.40.50.300 1 185 2.0E-52 T 23-10-2018 TON_1948 1440838a1cc587e0d446599a4e1e0b2a 203 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 2 177 1.8E-15 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 TON_1948 1440838a1cc587e0d446599a4e1e0b2a 203 Pfam PF01926 50S ribosome-binding GTPase 2 129 3.0E-19 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 TON_1948 1440838a1cc587e0d446599a4e1e0b2a 203 Hamap MF_00321 Probable GTP-binding protein EngB [engB]. 1 180 21.673 T 23-10-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 TON_1948 1440838a1cc587e0d446599a4e1e0b2a 203 SUPERFAMILY SSF52540 2 182 3.82E-33 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_0543 7a124276243ac668411babb352a44563 168 Pfam PF00037 4Fe-4S binding domain 7 23 1.4E-4 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TON_0543 7a124276243ac668411babb352a44563 168 Gene3D G3DSA:3.30.70.20 26 159 3.2E-40 T 23-10-2018 TON_0543 7a124276243ac668411babb352a44563 168 PRINTS PR00354 7Fe ferredoxin signature 48 58 2.5E-5 T 23-10-2018 IPR000813 7Fe ferredoxin GO:0009055 TON_0543 7a124276243ac668411babb352a44563 168 PRINTS PR00354 7Fe ferredoxin signature 75 92 2.5E-5 T 23-10-2018 IPR000813 7Fe ferredoxin GO:0009055 TON_0543 7a124276243ac668411babb352a44563 168 PRINTS PR00354 7Fe ferredoxin signature 58 68 2.5E-5 T 23-10-2018 IPR000813 7Fe ferredoxin GO:0009055 TON_0543 7a124276243ac668411babb352a44563 168 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 80 91 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TON_0543 7a124276243ac668411babb352a44563 168 Pfam PF13247 4Fe-4S dicluster domain 44 135 6.8E-27 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TON_0543 7a124276243ac668411babb352a44563 168 SUPERFAMILY SSF54862 1 149 1.67E-50 T 23-10-2018 TON_0196 eb24fb60df2af0d659c1dacffdc9983c 205 Hamap MF_00165 Thymidylate kinase [tmk]. 1 202 28.385 T 23-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 TON_0196 eb24fb60df2af0d659c1dacffdc9983c 205 ProSitePatterns PS01331 Thymidylate kinase signature. 96 108 - T 23-10-2018 IPR018095 Thymidylate kinase, conserved site GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 TON_0196 eb24fb60df2af0d659c1dacffdc9983c 205 SUPERFAMILY SSF52540 1 199 2.07E-53 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_0196 eb24fb60df2af0d659c1dacffdc9983c 205 Gene3D G3DSA:3.40.50.300 1 202 2.6E-69 T 23-10-2018 TON_0196 eb24fb60df2af0d659c1dacffdc9983c 205 Pfam PF02223 Thymidylate kinase 5 194 6.4E-55 T 23-10-2018 IPR039430 Thymidylate kinase-like domain KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210 TON_0196 eb24fb60df2af0d659c1dacffdc9983c 205 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 1 194 7.4E-59 T 23-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 TON_0442 4e8bc295c43634bee5c9065f10f03d12 410 Hamap MF_01402_A 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [apgM]. 3 401 45.508 T 23-10-2018 IPR023665 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, prokaryotes GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TON_0442 4e8bc295c43634bee5c9065f10f03d12 410 SUPERFAMILY SSF53649 3 403 2.62E-44 T 23-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 TON_0442 4e8bc295c43634bee5c9065f10f03d12 410 PIRSF PIRSF006392 1 406 4.3E-155 T 23-10-2018 IPR004456 2,3-bisphosphoglycerate-independent phosphoglycerate mutase GO:0003824|GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TON_0442 4e8bc295c43634bee5c9065f10f03d12 410 TIGRFAM TIGR00306 apgM: phosphoglycerate mutase (2,3-diphosphoglycerate-independent), archaeal form 6 400 5.8E-137 T 23-10-2018 IPR004456 2,3-bisphosphoglycerate-independent phosphoglycerate mutase GO:0003824|GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TON_0442 4e8bc295c43634bee5c9065f10f03d12 410 Gene3D G3DSA:3.30.70.2130 80 229 6.0E-143 T 23-10-2018 TON_0442 4e8bc295c43634bee5c9065f10f03d12 410 Gene3D G3DSA:3.40.720.10 6 395 6.0E-143 T 23-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 TON_0442 4e8bc295c43634bee5c9065f10f03d12 410 Pfam PF10143 2,3-bisphosphoglycerate-independent phosphoglycerate mutase 39 207 4.3E-54 T 23-10-2018 IPR004456 2,3-bisphosphoglycerate-independent phosphoglycerate mutase GO:0003824|GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TON_0442 4e8bc295c43634bee5c9065f10f03d12 410 Pfam PF01676 Metalloenzyme superfamily 4 400 1.9E-55 T 23-10-2018 IPR006124 Metalloenzyme GO:0003824|GO:0046872 TON_1076 51467a01a15201dbd557426a0cc27124 146 TIGRFAM TIGR00640 acid_CoA_mut_C: methylmalonyl-CoA mutase C-terminal domain 6 138 5.1E-59 T 23-10-2018 IPR006159 Methylmalonyl-CoA mutase, C-terminal GO:0016853 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 TON_1076 51467a01a15201dbd557426a0cc27124 146 SUPERFAMILY SSF52242 5 131 1.57E-48 T 23-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 TON_1076 51467a01a15201dbd557426a0cc27124 146 Pfam PF02310 B12 binding domain 8 121 8.3E-23 T 23-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 TON_1076 51467a01a15201dbd557426a0cc27124 146 Gene3D G3DSA:3.40.50.280 1 144 7.1E-57 T 23-10-2018 TON_1135 9f32b9b9f89ac43f406be65a565cd473 215 Gene3D G3DSA:3.20.20.70 2 213 3.7E-54 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TON_1135 9f32b9b9f89ac43f406be65a565cd473 215 Hamap MF_00214 3-dehydroquinate dehydratase [aroD]. 1 211 31.632 T 23-10-2018 IPR001381 3-dehydroquinate dehydratase type I GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 TON_1135 9f32b9b9f89ac43f406be65a565cd473 215 SUPERFAMILY SSF51569 2 211 2.34E-51 T 23-10-2018 TON_1135 9f32b9b9f89ac43f406be65a565cd473 215 TIGRFAM TIGR01093 aroD: 3-dehydroquinate dehydratase, type I 7 207 1.3E-44 T 23-10-2018 IPR001381 3-dehydroquinate dehydratase type I GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 TON_1135 9f32b9b9f89ac43f406be65a565cd473 215 Pfam PF01487 Type I 3-dehydroquinase 7 207 3.2E-51 T 23-10-2018 IPR001381 3-dehydroquinate dehydratase type I GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 TON_1472 61036c8cce1e0768588fd83e71aeda11 111 SUPERFAMILY SSF46934 69 110 1.83E-8 T 23-10-2018 IPR009060 UBA-like superfamily GO:0005515 TON_1472 61036c8cce1e0768588fd83e71aeda11 111 TIGRFAM TIGR00264 TIGR00264: alpha-NAC homolog 3 110 8.1E-35 T 23-10-2018 IPR005231 Nascent polypeptide-associated complex (NAC), archaeal GO:0003723 TON_1472 61036c8cce1e0768588fd83e71aeda11 111 Hamap MF_00814 Nascent polypeptide-associated complex protein [nac]. 7 109 20.337 T 23-10-2018 IPR005231 Nascent polypeptide-associated complex (NAC), archaeal GO:0003723 TON_1472 61036c8cce1e0768588fd83e71aeda11 111 Pfam PF01849 NAC domain 6 61 2.5E-9 T 23-10-2018 IPR002715 Nascent polypeptide-associated complex NAC domain TON_1472 61036c8cce1e0768588fd83e71aeda11 111 SMART SM01407 6 66 3.3E-15 T 23-10-2018 IPR002715 Nascent polypeptide-associated complex NAC domain TON_1472 61036c8cce1e0768588fd83e71aeda11 111 Gene3D G3DSA:1.10.8.10 70 109 2.2E-20 T 23-10-2018 TON_1472 61036c8cce1e0768588fd83e71aeda11 111 Gene3D G3DSA:2.20.70.30 10 68 3.5E-18 T 23-10-2018 IPR038187 NAC A/B domain superfamily TON_0563 9ac2600c023a8f334f39a32d69417c90 285 Hamap MF_00188 Protease HtpX [htpX]. 6 277 25.714 T 23-10-2018 IPR022919 Peptidase M48, protease HtpX, putative GO:0004222 TON_0563 9ac2600c023a8f334f39a32d69417c90 285 Pfam PF01435 Peptidase family M48 70 276 4.2E-30 T 23-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 TON_0563 9ac2600c023a8f334f39a32d69417c90 285 Gene3D G3DSA:3.30.2010.10 60 150 6.5E-26 T 23-10-2018 TON_1512 bef022d9f8c4684826bba5b588f6aafa 71 SUPERFAMILY SSF46785 12 58 2.25E-5 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TON_1407 3a2f283d4c061e2667643b0543cc21ab 224 SUPERFAMILY SSF52540 2 219 2.14E-39 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_1407 3a2f283d4c061e2667643b0543cc21ab 224 Hamap MF_00350 DNA repair and recombination protein RadB [radB]. 8 217 36.751 T 23-10-2018 IPR011939 DNA repair and recombination protein RadB GO:0003684|GO:0005524|GO:0006281|GO:0006310 TON_1407 3a2f283d4c061e2667643b0543cc21ab 224 Gene3D G3DSA:3.40.50.300 7 220 7.5E-61 T 23-10-2018 TON_1407 3a2f283d4c061e2667643b0543cc21ab 224 TIGRFAM TIGR02237 recomb_radB: DNA repair and recombination protein RadB 9 217 4.0E-69 T 23-10-2018 IPR011939 DNA repair and recombination protein RadB GO:0003684|GO:0005524|GO:0006281|GO:0006310 TON_1407 3a2f283d4c061e2667643b0543cc21ab 224 PIRSF PIRSF003336 1 220 1.4E-97 T 23-10-2018 IPR011939 DNA repair and recombination protein RadB GO:0003684|GO:0005524|GO:0006281|GO:0006310 TON_1407 3a2f283d4c061e2667643b0543cc21ab 224 Pfam PF08423 Rad51 2 218 2.4E-31 T 23-10-2018 IPR013632 DNA recombination and repair protein Rad51-like, C-terminal Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579 TON_1407 3a2f283d4c061e2667643b0543cc21ab 224 PRINTS PR01874 DNA repair protein radA signature 11 39 1.1E-6 T 23-10-2018 TON_1407 3a2f283d4c061e2667643b0543cc21ab 224 PRINTS PR01874 DNA repair protein radA signature 190 216 1.1E-6 T 23-10-2018 TON_0095 3981cc66350d147c1bc387e9ccb1dd5d 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 144 163 9.2E-15 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TON_0095 3981cc66350d147c1bc387e9ccb1dd5d 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 182 9.2E-15 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TON_0095 3981cc66350d147c1bc387e9ccb1dd5d 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 9.2E-15 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TON_0095 3981cc66350d147c1bc387e9ccb1dd5d 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 73 84 9.2E-15 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TON_0095 3981cc66350d147c1bc387e9ccb1dd5d 235 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 73 84 7.1E-6 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TON_0095 3981cc66350d147c1bc387e9ccb1dd5d 235 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 124 132 7.1E-6 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TON_0095 3981cc66350d147c1bc387e9ccb1dd5d 235 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 144 163 7.1E-6 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TON_0095 3981cc66350d147c1bc387e9ccb1dd5d 235 Gene3D G3DSA:3.40.50.720 1 231 1.7E-49 T 23-10-2018 TON_0095 3981cc66350d147c1bc387e9ccb1dd5d 235 Pfam PF00106 short chain dehydrogenase 2 185 1.4E-35 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TON_0095 3981cc66350d147c1bc387e9ccb1dd5d 235 SUPERFAMILY SSF51735 1 214 8.87E-46 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TON_1355 09c5a78eb8512df9fbffc05e92a9d05e 656 Pfam PF00082 Subtilase family 156 426 7.8E-67 T 23-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 TON_1355 09c5a78eb8512df9fbffc05e92a9d05e 656 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 161 172 - T 23-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site TON_1355 09c5a78eb8512df9fbffc05e92a9d05e 656 PRINTS PR00723 Subtilisin serine protease family (S8) signature 194 207 7.4E-25 T 23-10-2018 IPR015500 Peptidase S8, subtilisin-related TON_1355 09c5a78eb8512df9fbffc05e92a9d05e 656 PRINTS PR00723 Subtilisin serine protease family (S8) signature 156 175 7.4E-25 T 23-10-2018 IPR015500 Peptidase S8, subtilisin-related TON_1355 09c5a78eb8512df9fbffc05e92a9d05e 656 PRINTS PR00723 Subtilisin serine protease family (S8) signature 374 390 7.4E-25 T 23-10-2018 IPR015500 Peptidase S8, subtilisin-related TON_1355 09c5a78eb8512df9fbffc05e92a9d05e 656 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 375 385 - T 23-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site TON_1355 09c5a78eb8512df9fbffc05e92a9d05e 656 Gene3D G3DSA:3.30.70.80 39 130 9.0E-43 T 23-10-2018 IPR037045 Peptidase S8 propeptide/proteinase inhibitor I9 superfamily Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 TON_1355 09c5a78eb8512df9fbffc05e92a9d05e 656 SUPERFAMILY SSF52743 140 436 4.58E-94 T 23-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 TON_1355 09c5a78eb8512df9fbffc05e92a9d05e 656 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 198 208 - T 23-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site TON_1355 09c5a78eb8512df9fbffc05e92a9d05e 656 PIRSF PIRSF037907 1 656 0.0 T 23-10-2018 IPR017319 Subtilisin-like serine protease TK1689-type TON_1355 09c5a78eb8512df9fbffc05e92a9d05e 656 Gene3D G3DSA:2.60.120.380 556 654 3.0E-15 T 23-10-2018 TON_1355 09c5a78eb8512df9fbffc05e92a9d05e 656 Gene3D G3DSA:2.60.120.380 439 539 3.4E-21 T 23-10-2018 TON_1355 09c5a78eb8512df9fbffc05e92a9d05e 656 Pfam PF04151 Bacterial pre-peptidase C-terminal domain 571 637 2.0E-7 T 23-10-2018 IPR007280 Peptidase, C-terminal, archaeal/bacterial TON_1355 09c5a78eb8512df9fbffc05e92a9d05e 656 Gene3D G3DSA:3.40.50.200 131 438 1.6E-135 T 23-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 TON_1355 09c5a78eb8512df9fbffc05e92a9d05e 656 SUPERFAMILY SSF49785 446 522 1.79E-6 T 23-10-2018 IPR008979 Galactose-binding-like domain superfamily TON_1276 bb40bffd5bf684b0b634201e72ba098b 387 Pfam PF01435 Peptidase family M48 191 383 4.6E-24 T 23-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 TON_1276 bb40bffd5bf684b0b634201e72ba098b 387 Gene3D G3DSA:3.30.2010.10 188 265 1.0E-13 T 23-10-2018 TON_1798 85ebd55d8c07a7a0dad97c4e3136110b 450 SUPERFAMILY SSF53756 1 439 3.21E-89 T 23-10-2018 TON_1798 85ebd55d8c07a7a0dad97c4e3136110b 450 Pfam PF00534 Glycosyl transferases group 1 252 420 1.8E-23 T 23-10-2018 IPR001296 Glycosyl transferase, family 1 TON_1798 85ebd55d8c07a7a0dad97c4e3136110b 450 Gene3D G3DSA:3.40.50.2000 220 428 7.6E-115 T 23-10-2018 TON_1798 85ebd55d8c07a7a0dad97c4e3136110b 450 Gene3D G3DSA:3.40.50.2000 2 438 7.6E-115 T 23-10-2018 TON_1798 85ebd55d8c07a7a0dad97c4e3136110b 450 Pfam PF08323 Starch synthase catalytic domain 2 205 2.0E-36 T 23-10-2018 IPR013534 Starch synthase, catalytic domain KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 TON_1891 c5beb726394723f42356de209f30a039 197 Pfam PF01174 SNO glutamine amidotransferase family 6 195 4.1E-60 T 23-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 TON_1891 c5beb726394723f42356de209f30a039 197 Hamap MF_01615 Pyridoxal 5'-phosphate synthase subunit PdxT [pdxT]. 4 195 36.329 T 23-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 TON_1891 c5beb726394723f42356de209f30a039 197 PIRSF PIRSF005639 1 197 1.1E-69 T 23-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 TON_1891 c5beb726394723f42356de209f30a039 197 Gene3D G3DSA:3.40.50.880 1 197 3.1E-70 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like TON_1891 c5beb726394723f42356de209f30a039 197 TIGRFAM TIGR03800 PLP_synth_Pdx2: pyridoxal 5'-phosphate synthase, glutaminase subunit Pdx2 3 193 7.7E-75 T 23-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 TON_1891 c5beb726394723f42356de209f30a039 197 ProSitePatterns PS01236 PdxT/SNO family family signature. 47 57 - T 23-10-2018 IPR021196 PdxT/SNO family, conserved site KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 TON_1891 c5beb726394723f42356de209f30a039 197 SUPERFAMILY SSF52317 3 194 1.36E-50 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like TON_1138 71a99e7c9fc161edef906de75f3ce8e3 402 ProSitePatterns PS00885 EPSP synthase signature 2. 315 333 - T 23-10-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 TON_1138 71a99e7c9fc161edef906de75f3ce8e3 402 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 13 401 8.1E-121 T 23-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 TON_1138 71a99e7c9fc161edef906de75f3ce8e3 402 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 9 402 31.258 T 23-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 TON_1138 71a99e7c9fc161edef906de75f3ce8e3 402 Gene3D G3DSA:3.65.10.10 21 218 1.4E-115 T 23-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 TON_1138 71a99e7c9fc161edef906de75f3ce8e3 402 Gene3D G3DSA:3.65.10.10 13 394 1.4E-115 T 23-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 TON_1138 71a99e7c9fc161edef906de75f3ce8e3 402 SUPERFAMILY SSF55205 4 400 1.11E-104 T 23-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 TON_1138 71a99e7c9fc161edef906de75f3ce8e3 402 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 6 397 3.4E-95 T 23-10-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 TON_1138 71a99e7c9fc161edef906de75f3ce8e3 402 PIRSF PIRSF000505 3 402 1.2E-128 T 23-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 TON_1882 e364ef4958d601466b2eae447932dc56 660 SUPERFAMILY SSF52540 164 639 9.25E-67 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_1882 e364ef4958d601466b2eae447932dc56 660 Gene3D G3DSA:3.40.50.300 448 656 4.8E-62 T 23-10-2018 TON_1882 e364ef4958d601466b2eae447932dc56 660 Gene3D G3DSA:3.40.50.300 12 431 8.2E-94 T 23-10-2018 TON_1882 e364ef4958d601466b2eae447932dc56 660 Pfam PF13087 AAA domain 425 626 1.6E-57 T 23-10-2018 TON_1882 e364ef4958d601466b2eae447932dc56 660 Gene3D G3DSA:2.40.30.270 29 123 8.2E-94 T 23-10-2018 TON_1882 e364ef4958d601466b2eae447932dc56 660 TIGRFAM TIGR00376 TIGR00376: putative DNA helicase 15 651 5.6E-248 T 23-10-2018 IPR004483 Helicase SMUBP-2/Hcs1-like GO:0003677|GO:0005524 TON_1882 e364ef4958d601466b2eae447932dc56 660 Pfam PF13086 AAA domain 171 420 1.4E-56 T 23-10-2018 TON_1882 e364ef4958d601466b2eae447932dc56 660 SMART SM00382 185 435 0.0027 T 23-10-2018 IPR003593 AAA+ ATPase domain TON_1904 89df6e2daf7851e3733f7c2cb06a8965 739 Gene3D G3DSA:1.50.10.20 107 234 2.1E-6 T 23-10-2018 TON_1904 89df6e2daf7851e3733f7c2cb06a8965 739 SUPERFAMILY SSF48239 69 356 2.27E-26 T 23-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid TON_1904 89df6e2daf7851e3733f7c2cb06a8965 739 Pfam PF00432 Prenyltransferase and squalene oxidase repeat 306 336 4.0E-4 T 23-10-2018 IPR001330 PFTB repeat GO:0003824 TON_1904 89df6e2daf7851e3733f7c2cb06a8965 739 Pfam PF00432 Prenyltransferase and squalene oxidase repeat 66 102 3.5E-4 T 23-10-2018 IPR001330 PFTB repeat GO:0003824 TON_1904 89df6e2daf7851e3733f7c2cb06a8965 739 Gene3D G3DSA:1.50.10.20 44 106 3.2E-9 T 23-10-2018 TON_1904 89df6e2daf7851e3733f7c2cb06a8965 739 SUPERFAMILY SSF48239 308 516 5.57E-23 T 23-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid TON_1904 89df6e2daf7851e3733f7c2cb06a8965 739 Gene3D G3DSA:1.50.10.20 380 527 1.2E-14 T 23-10-2018 TON_1904 89df6e2daf7851e3733f7c2cb06a8965 739 Gene3D G3DSA:1.50.10.20 263 379 6.5E-12 T 23-10-2018 TON_0701 100c78bd24713dae2157f3b3ebcdb6b5 335 Pfam PF01916 Deoxyhypusine synthase 34 331 5.7E-111 T 23-10-2018 IPR002773 Deoxyhypusine synthase GO:0008612 Reactome: R-HSA-204626 TON_0701 100c78bd24713dae2157f3b3ebcdb6b5 335 Gene3D G3DSA:3.40.910.10 2 335 1.1E-143 T 23-10-2018 IPR036982 Deoxyhypusine synthase superfamily GO:0008612 Reactome: R-HSA-204626 TON_0701 100c78bd24713dae2157f3b3ebcdb6b5 335 TIGRFAM TIGR00321 dhys: deoxyhypusine synthase 20 334 1.1E-121 T 23-10-2018 IPR002773 Deoxyhypusine synthase GO:0008612 Reactome: R-HSA-204626 TON_0701 100c78bd24713dae2157f3b3ebcdb6b5 335 Hamap MF_00153 Probable deoxyhypusine synthase [dys]. 31 334 42.669 T 23-10-2018 IPR022899 Deoxyhypusine synthase, putative, archaeal GO:0034038 TON_0701 100c78bd24713dae2157f3b3ebcdb6b5 335 SUPERFAMILY SSF52467 5 334 1.73E-114 T 23-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily TON_1026 b9a4878bdd62f9618ffc1cedf306be68 119 TIGRFAM TIGR01300 CPA3_mnhG_phaG: monovalent cation/proton antiporter, MnhG/PhaG subunit 11 111 2.9E-27 T 23-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 TON_1026 b9a4878bdd62f9618ffc1cedf306be68 119 Pfam PF03334 Na+/H+ antiporter subunit 12 98 4.8E-17 T 23-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 TON_1422 07ae899d86422aa4fb03907554c7cf52 884 Gene3D G3DSA:1.10.287.510 391 502 1.0E-25 T 23-10-2018 TON_1422 07ae899d86422aa4fb03907554c7cf52 884 Gene3D G3DSA:3.40.50.300 1 216 4.5E-47 T 23-10-2018 TON_1422 07ae899d86422aa4fb03907554c7cf52 884 Gene3D G3DSA:3.40.50.300 677 880 2.0E-44 T 23-10-2018 TON_1422 07ae899d86422aa4fb03907554c7cf52 884 Pfam PF04423 Rad50 zinc hook motif 419 470 6.5E-12 T 23-10-2018 IPR013134 RAD50, zinc hook Reactome: R-HSA-2559586|Reactome: R-HSA-5685938|Reactome: R-HSA-5685939|Reactome: R-HSA-5685942|Reactome: R-HSA-5693548|Reactome: R-HSA-5693554|Reactome: R-HSA-5693565|Reactome: R-HSA-5693568|Reactome: R-HSA-5693571|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 TON_1422 07ae899d86422aa4fb03907554c7cf52 884 SMART SM00382 22 872 0.0011 T 23-10-2018 IPR003593 AAA+ ATPase domain TON_1422 07ae899d86422aa4fb03907554c7cf52 884 SUPERFAMILY SSF52540 1 314 2.42E-15 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_1422 07ae899d86422aa4fb03907554c7cf52 884 SUPERFAMILY SSF75712 395 488 3.14E-18 T 23-10-2018 TON_1422 07ae899d86422aa4fb03907554c7cf52 884 Hamap MF_00449 DNA double-strand break repair Rad50 ATPase [rad50]. 1 879 13.555 T 23-10-2018 IPR022982 DNA double-strand break repair Rad50 ATPase, archaeal type TON_1422 07ae899d86422aa4fb03907554c7cf52 884 Pfam PF13476 AAA domain 5 202 1.0E-21 T 23-10-2018 IPR038729 Rad50/SbcC-type AAA domain TON_1422 07ae899d86422aa4fb03907554c7cf52 884 SUPERFAMILY SSF52540 1 868 3.62E-35 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_0717 38cb2e33542b3bffe03c5b1ce4b628cc 297 Hamap MF_01222 Protein archease. 157 297 41.76 T 23-10-2018 IPR022952 Archease, archaea TON_0717 38cb2e33542b3bffe03c5b1ce4b628cc 297 Pfam PF01951 Archease protein family (MTH1598/TM1083) 159 296 4.1E-45 T 23-10-2018 IPR023572 Archease domain Reactome: R-HSA-6784531 TON_0717 38cb2e33542b3bffe03c5b1ce4b628cc 297 Gene3D G3DSA:3.55.10.10 155 297 8.8E-52 T 23-10-2018 IPR036820 Archease domain superfamily Reactome: R-HSA-6784531 TON_0717 38cb2e33542b3bffe03c5b1ce4b628cc 297 SUPERFAMILY SSF69819 157 297 2.22E-46 T 23-10-2018 IPR036820 Archease domain superfamily Reactome: R-HSA-6784531 TON_0717 38cb2e33542b3bffe03c5b1ce4b628cc 297 ProDom PD012969 UPF0211 RIKEN CDNA ENRICHED MALE FULL-LENGTH LIBRARY ZBTB8OS ADULT C43H8.1 163 297 8.0E-31 T 23-10-2018 IPR023572 Archease domain Reactome: R-HSA-6784531 TON_1553 892236bd5b503200c469b248401d2155 545 Pfam PF00149 Calcineurin-like phosphoesterase 314 492 1.8E-11 T 23-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 TON_1553 892236bd5b503200c469b248401d2155 545 SUPERFAMILY SSF56300 321 543 2.8E-32 T 23-10-2018 TON_1553 892236bd5b503200c469b248401d2155 545 Gene3D G3DSA:3.60.21.10 308 536 2.8E-21 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like TON_0642 3218da591d28d31afc906d27550f7131 168 Pfam PF04167 Protein of unknown function (DUF402) 55 121 7.6E-14 T 23-10-2018 IPR007295 Domain of unknown function DUF402 TON_0642 3218da591d28d31afc906d27550f7131 168 Gene3D G3DSA:2.40.380.10 27 164 1.7E-13 T 23-10-2018 IPR035930 FomD-like superfamily TON_0642 3218da591d28d31afc906d27550f7131 168 SUPERFAMILY SSF159234 2 162 5.89E-40 T 23-10-2018 IPR035930 FomD-like superfamily TON_0918 d2ba5747cdb25910cfdde8fbeb82358e 179 PIRSF PIRSF037213 4 178 2.9E-56 T 23-10-2018 IPR017139 Uncharacterised conserved protein UCP037213 TON_0918 d2ba5747cdb25910cfdde8fbeb82358e 179 Pfam PF10007 Uncharacterized protein conserved in archaea (DUF2250) 15 105 5.2E-33 T 23-10-2018 IPR019254 Protein of unknown function DUF2250 TON_0918 d2ba5747cdb25910cfdde8fbeb82358e 179 Gene3D G3DSA:1.10.10.10 19 113 4.6E-5 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TON_0461 9da74b013bbcaa5f85c2d46e57b7b3dd 315 Gene3D G3DSA:2.20.28.30 1 38 2.1E-7 T 23-10-2018 TON_0461 9da74b013bbcaa5f85c2d46e57b7b3dd 315 SUPERFAMILY SSF63393 3 30 6.28E-5 T 23-10-2018 IPR029040 RNA polymerase subunit RPABC4/transcription elongation factor Spt4 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-75955 TON_0321 fa01e032aa0e094ddb67087902756748 222 Gene3D G3DSA:3.90.320.10 8 220 3.7E-19 T 23-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal TON_1483 f7765db43b6ebf3b15182b8fbf520ff0 305 Hamap MF_02040 Iron-sulfur cluster carrier protein. 21 283 37.278 T 23-10-2018 IPR019591 Mrp/NBP35 ATP-binding protein TON_1483 f7765db43b6ebf3b15182b8fbf520ff0 305 ProSitePatterns PS01215 Mrp family signature. 147 163 - T 23-10-2018 IPR000808 Mrp, conserved site GO:0005524 TON_1483 f7765db43b6ebf3b15182b8fbf520ff0 305 Gene3D G3DSA:3.40.50.300 18 282 2.9E-82 T 23-10-2018 TON_1483 f7765db43b6ebf3b15182b8fbf520ff0 305 SUPERFAMILY SSF52540 20 267 3.27E-59 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_1483 f7765db43b6ebf3b15182b8fbf520ff0 305 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 31 282 1.9E-96 T 23-10-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 TON_1174 3fac1a29b8de8159c620e0c303ba2e3a 376 Pfam PF01478 Type IV leader peptidase family 8 126 1.9E-5 T 23-10-2018 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 TON_1174 3fac1a29b8de8159c620e0c303ba2e3a 376 Gene3D G3DSA:1.20.120.1220 1 145 2.3E-20 T 23-10-2018 TON_1174 3fac1a29b8de8159c620e0c303ba2e3a 376 Pfam PF06819 Archaeal Peptidase A24 C-terminal Domain 232 340 3.6E-28 T 23-10-2018 IPR009639 Peptidase A24A-predicted, C-terminal archaea TON_1605 60b3db0d44ac7350144d8c75a2bc50ad 445 Gene3D G3DSA:3.90.1150.10 14 438 2.9E-150 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TON_1605 60b3db0d44ac7350144d8c75a2bc50ad 445 Pfam PF00202 Aminotransferase class-III 34 438 1.9E-115 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TON_1605 60b3db0d44ac7350144d8c75a2bc50ad 445 PIRSF PIRSF000521 2 138 3.9E-8 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TON_1605 60b3db0d44ac7350144d8c75a2bc50ad 445 PIRSF PIRSF000521 136 443 2.9E-55 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TON_1605 60b3db0d44ac7350144d8c75a2bc50ad 445 SUPERFAMILY SSF53383 33 441 2.3E-124 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TON_1605 60b3db0d44ac7350144d8c75a2bc50ad 445 Gene3D G3DSA:3.40.640.10 72 340 2.9E-150 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TON_0814 a53260d8ba13b5d3be80c184c20b6898 407 Gene3D G3DSA:3.40.50.2000 179 361 1.4E-86 T 23-10-2018 TON_0814 a53260d8ba13b5d3be80c184c20b6898 407 Pfam PF13439 Glycosyltransferase Family 4 17 182 3.8E-28 T 23-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 TON_0814 a53260d8ba13b5d3be80c184c20b6898 407 SUPERFAMILY SSF53756 5 379 3.93E-91 T 23-10-2018 TON_0814 a53260d8ba13b5d3be80c184c20b6898 407 Pfam PF00534 Glycosyl transferases group 1 190 355 2.4E-38 T 23-10-2018 IPR001296 Glycosyl transferase, family 1 TON_0814 a53260d8ba13b5d3be80c184c20b6898 407 Gene3D G3DSA:3.40.50.2000 17 370 1.4E-86 T 23-10-2018 TON_1253 c4a2b1660f8c63662bbfe9999850f5e4 150 Pfam PF01467 Cytidylyltransferase-like 12 143 7.8E-23 T 23-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 TON_1253 c4a2b1660f8c63662bbfe9999850f5e4 150 Gene3D G3DSA:3.40.50.620 1 150 3.3E-41 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TON_1253 c4a2b1660f8c63662bbfe9999850f5e4 150 Hamap MF_02115 FAD synthase [ribL]. 9 149 30.617 T 23-10-2018 IPR024902 FAD synthase RibL GO:0003919|GO:0006747|GO:0046444 KEGG: 00740+2.7.7.2|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TON_1253 c4a2b1660f8c63662bbfe9999850f5e4 150 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 10 76 1.3E-19 T 23-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 TON_1253 c4a2b1660f8c63662bbfe9999850f5e4 150 SUPERFAMILY SSF52374 9 144 8.3E-27 T 23-10-2018 TON_1628 89e15952477674e52ac682c5aafe1722 299 Pfam PF03168 Late embryogenesis abundant protein 183 265 1.1E-13 T 23-10-2018 IPR004864 Late embryogenesis abundant protein, LEA_2 subgroup TON_1628 89e15952477674e52ac682c5aafe1722 299 Gene3D G3DSA:2.60.40.10 30 147 1.4E-10 T 23-10-2018 IPR013783 Immunoglobulin-like fold TON_1628 89e15952477674e52ac682c5aafe1722 299 Gene3D G3DSA:2.60.40.10 162 293 2.8E-32 T 23-10-2018 IPR013783 Immunoglobulin-like fold TON_1628 89e15952477674e52ac682c5aafe1722 299 SMART SM00769 29 143 0.28 T 23-10-2018 IPR013990 Water stress and hypersensitive response domain GO:0009269 TON_1628 89e15952477674e52ac682c5aafe1722 299 SMART SM00769 163 280 7.6E-21 T 23-10-2018 IPR013990 Water stress and hypersensitive response domain GO:0009269 TON_1628 89e15952477674e52ac682c5aafe1722 299 SUPERFAMILY SSF117070 157 259 1.83E-19 T 23-10-2018 TON_1878 2a7bd0ac20529dfbd5e4bc259463f88b 355 SUPERFAMILY SSF53067 1 308 1.68E-8 T 23-10-2018 TON_1878 2a7bd0ac20529dfbd5e4bc259463f88b 355 Pfam PF07318 Protein of unknown function (DUF1464) 5 351 1.6E-130 T 23-10-2018 IPR009927 Protein of unknown function DUF1464 TON_1878 2a7bd0ac20529dfbd5e4bc259463f88b 355 PIRSF PIRSF009433 1 354 3.0E-142 T 23-10-2018 IPR009927 Protein of unknown function DUF1464 TON_0117 52e6b4c67bae130e4ece04b061f0e26c 253 Gene3D G3DSA:3.60.21.10 3 253 2.6E-51 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like TON_0117 52e6b4c67bae130e4ece04b061f0e26c 253 SUPERFAMILY SSF56300 3 252 6.83E-59 T 23-10-2018 TON_0117 52e6b4c67bae130e4ece04b061f0e26c 253 PIRSF PIRSF000883 4 253 1.2E-26 T 23-10-2018 IPR011152 Phosphoesterase MJ0912 TON_0104 ecd7e7882fc11d84dacf5ecf56dede05 139 Gene3D G3DSA:3.30.420.80 2 139 2.0E-65 T 23-10-2018 IPR036967 Ribosomal protein S11 superfamily GO:0003735|GO:0005840|GO:0006412 TON_0104 ecd7e7882fc11d84dacf5ecf56dede05 139 ProSitePatterns PS00054 Ribosomal protein S11 signature. 104 126 - T 23-10-2018 IPR018102 Ribosomal S11, conserved site TON_0104 ecd7e7882fc11d84dacf5ecf56dede05 139 SUPERFAMILY SSF53137 11 137 4.19E-39 T 23-10-2018 TON_0104 ecd7e7882fc11d84dacf5ecf56dede05 139 PIRSF PIRSF002131 1 138 1.1E-35 T 23-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 TON_0104 ecd7e7882fc11d84dacf5ecf56dede05 139 TIGRFAM TIGR03628 arch_S11P: ribosomal protein uS11 15 131 4.8E-67 T 23-10-2018 IPR019961 Ribosomal protein S11, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 TON_0104 ecd7e7882fc11d84dacf5ecf56dede05 139 Pfam PF00411 Ribosomal protein S11 17 135 1.5E-47 T 23-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 TON_0104 ecd7e7882fc11d84dacf5ecf56dede05 139 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 11 136 23.698 T 23-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 TON_0751 4864fb8cf36af2a068e2959122c83e0b 102 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 1 100 24.652 T 23-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0751 4864fb8cf36af2a068e2959122c83e0b 102 TIGRFAM TIGR01046 uS10_euk_arch: ribosomal protein uS10 2 100 2.6E-50 T 23-10-2018 IPR005729 Ribosomal protein S10, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0751 4864fb8cf36af2a068e2959122c83e0b 102 SMART SM01403 5 99 7.5E-41 T 23-10-2018 IPR027486 Ribosomal protein S10 domain TON_0751 4864fb8cf36af2a068e2959122c83e0b 102 Pfam PF00338 Ribosomal protein S10p/S20e 5 98 1.2E-27 T 23-10-2018 IPR027486 Ribosomal protein S10 domain TON_0751 4864fb8cf36af2a068e2959122c83e0b 102 PRINTS PR00971 Ribosomal protein S10 family signature 3 16 1.6E-16 T 23-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0751 4864fb8cf36af2a068e2959122c83e0b 102 PRINTS PR00971 Ribosomal protein S10 family signature 60 74 1.6E-16 T 23-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0751 4864fb8cf36af2a068e2959122c83e0b 102 PRINTS PR00971 Ribosomal protein S10 family signature 38 53 1.6E-16 T 23-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0751 4864fb8cf36af2a068e2959122c83e0b 102 SUPERFAMILY SSF54999 3 100 4.05E-29 T 23-10-2018 IPR036838 Ribosomal protein S10 domain superfamily TON_0751 4864fb8cf36af2a068e2959122c83e0b 102 Gene3D G3DSA:3.30.70.600 1 101 5.7E-35 T 23-10-2018 IPR036838 Ribosomal protein S10 domain superfamily TON_0751 4864fb8cf36af2a068e2959122c83e0b 102 ProSitePatterns PS00361 Ribosomal protein S10 signature. 27 42 - T 23-10-2018 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_1327 9525a93f2f8974cb8a686866f00824a4 85 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 2 83 3.3E-16 T 23-10-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like TON_1850 fedcdba1e1737b2e5e6cc10f626f2944 156 Pfam PF01850 PIN domain 7 134 4.1E-20 T 23-10-2018 IPR002716 PIN domain TON_1850 fedcdba1e1737b2e5e6cc10f626f2944 156 Gene3D G3DSA:3.40.50.1010 5 144 1.0E-7 T 23-10-2018 TON_1850 fedcdba1e1737b2e5e6cc10f626f2944 156 SUPERFAMILY SSF88723 5 134 3.64E-16 T 23-10-2018 IPR029060 PIN-like domain superfamily TON_1850 fedcdba1e1737b2e5e6cc10f626f2944 156 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 6 141 9.597 T 23-10-2018 IPR022907 VapC family GO:0004540 TON_1850 fedcdba1e1737b2e5e6cc10f626f2944 156 SMART SM00670 4 133 1.5E-11 T 23-10-2018 IPR002716 PIN domain TON_1064 9b54050f557fac3a026cb3cfa6a28430 147 SMART SM00465 17 113 3.4E-7 T 23-10-2018 IPR000305 GIY-YIG endonuclease TON_1064 9b54050f557fac3a026cb3cfa6a28430 147 Pfam PF01986 Domain of unknown function DUF123 26 110 1.9E-21 T 23-10-2018 IPR002837 Protein of unknown function DUF123 TON_0157 bd9c8fe657b45946cdaafad39723eb47 419 SUPERFAMILY SSF53223 4 184 1.34E-67 T 23-10-2018 TON_0157 bd9c8fe657b45946cdaafad39723eb47 419 Gene3D G3DSA:3.40.50.10860 36 180 3.5E-66 T 23-10-2018 TON_0157 bd9c8fe657b45946cdaafad39723eb47 419 SUPERFAMILY SSF51735 182 417 4.31E-82 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TON_0157 bd9c8fe657b45946cdaafad39723eb47 419 Gene3D G3DSA:3.40.50.720 182 418 1.4E-96 T 23-10-2018 TON_0157 bd9c8fe657b45946cdaafad39723eb47 419 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 99 112 - T 23-10-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 TON_0157 bd9c8fe657b45946cdaafad39723eb47 419 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 173 195 3.6E-30 T 23-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 TON_0157 bd9c8fe657b45946cdaafad39723eb47 419 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 215 235 3.6E-30 T 23-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 TON_0157 bd9c8fe657b45946cdaafad39723eb47 419 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 343 354 3.6E-30 T 23-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 TON_0157 bd9c8fe657b45946cdaafad39723eb47 419 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 91 105 3.6E-30 T 23-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 TON_0157 bd9c8fe657b45946cdaafad39723eb47 419 PIRSF PIRSF000185 1 418 1.9E-174 T 23-10-2018 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 TON_0157 bd9c8fe657b45946cdaafad39723eb47 419 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 182 415 1.9E-75 T 23-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 TON_0157 bd9c8fe657b45946cdaafad39723eb47 419 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 34 161 4.2E-53 T 23-10-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 TON_0157 bd9c8fe657b45946cdaafad39723eb47 419 SMART SM00839 184 415 7.2E-99 T 23-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 TON_0092 cb3dd32b44c58bc313a4b2da2cdbe468 90 PRINTS PR01250 Ribosomal protein L34 signature 56 78 1.0E-17 T 23-10-2018 IPR008195 Ribosomal protein L34Ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0092 cb3dd32b44c58bc313a4b2da2cdbe468 90 PRINTS PR01250 Ribosomal protein L34 signature 36 46 1.0E-17 T 23-10-2018 IPR008195 Ribosomal protein L34Ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0092 cb3dd32b44c58bc313a4b2da2cdbe468 90 PRINTS PR01250 Ribosomal protein L34 signature 5 18 1.0E-17 T 23-10-2018 IPR008195 Ribosomal protein L34Ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0092 cb3dd32b44c58bc313a4b2da2cdbe468 90 PRINTS PR01250 Ribosomal protein L34 signature 18 35 1.0E-17 T 23-10-2018 IPR008195 Ribosomal protein L34Ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0092 cb3dd32b44c58bc313a4b2da2cdbe468 90 Pfam PF01199 Ribosomal protein L34e 3 83 2.9E-25 T 23-10-2018 IPR008195 Ribosomal protein L34Ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0092 cb3dd32b44c58bc313a4b2da2cdbe468 90 ProSitePatterns PS01145 Ribosomal protein L34e signature. 7 20 - T 23-10-2018 IPR018065 Ribosomal protein L34e, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0092 cb3dd32b44c58bc313a4b2da2cdbe468 90 Hamap MF_00349 50S ribosomal protein L34e [rpl34e]. 1 86 29.048 T 23-10-2018 IPR008195 Ribosomal protein L34Ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0092 cb3dd32b44c58bc313a4b2da2cdbe468 90 Gene3D G3DSA:3.40.1800.40 29 86 1.3E-10 T 23-10-2018 IPR038562 Ribosomal protein L34Ae superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0665 695290d43839f2977989d65bf40d095c 330 SUPERFAMILY SSF51445 38 249 3.48E-30 T 23-10-2018 IPR017853 Glycoside hydrolase superfamily TON_0665 695290d43839f2977989d65bf40d095c 330 Pfam PF03537 Glycoside-hydrolase family GH114 75 277 2.7E-18 T 23-10-2018 IPR004352 Glycoside-hydrolase family GH114, TIM-barrel domain TON_0665 695290d43839f2977989d65bf40d095c 330 Gene3D G3DSA:3.20.20.70 55 284 3.7E-25 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TON_0554 7e5271ed17e8eb29e87f5488eceb7c72 487 SUPERFAMILY SSF64182 162 453 1.22E-54 T 23-10-2018 IPR038763 DHH phosphoesterase superfamily TON_0554 7e5271ed17e8eb29e87f5488eceb7c72 487 Gene3D G3DSA:3.90.1640.10 163 366 2.8E-25 T 23-10-2018 TON_0554 7e5271ed17e8eb29e87f5488eceb7c72 487 Pfam PF02254 TrkA-N domain 3 109 6.0E-20 T 23-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 TON_0554 7e5271ed17e8eb29e87f5488eceb7c72 487 SUPERFAMILY SSF51735 1 138 2.5E-20 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TON_0554 7e5271ed17e8eb29e87f5488eceb7c72 487 Pfam PF02272 DHHA1 domain 355 471 3.9E-14 T 23-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 TON_0554 7e5271ed17e8eb29e87f5488eceb7c72 487 Pfam PF01368 DHH family 165 315 5.6E-8 T 23-10-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 TON_0554 7e5271ed17e8eb29e87f5488eceb7c72 487 Gene3D G3DSA:3.40.50.720 1 140 2.4E-22 T 23-10-2018 TON_0432 87edd8055783a53ea2d206583c819fd6 223 Gene3D G3DSA:3.40.50.11570 1 211 1.6E-50 T 23-10-2018 TON_0432 87edd8055783a53ea2d206583c819fd6 223 Pfam PF03192 Pyrococcus protein of unknown function, DUF257 6 207 1.2E-46 T 23-10-2018 IPR005489 Protein of unknown function DUF257 TON_1492 3ff3026ee75d2be897d54bb34c513091 202 ProDom PD016744 UPF0215 ST0304 TK2033 MA4269 PAE0952 SSO0256 NEQ431 MK0057 PTO0905 TV0037 79 191 3.0E-42 T 23-10-2018 IPR002802 Protein of unknown function DUF99 TON_1492 3ff3026ee75d2be897d54bb34c513091 202 Gene3D G3DSA:3.30.2170.10 10 202 8.9E-60 T 23-10-2018 TON_1492 3ff3026ee75d2be897d54bb34c513091 202 PIRSF PIRSF006380 4 202 1.5E-69 T 23-10-2018 IPR002802 Protein of unknown function DUF99 TON_1492 3ff3026ee75d2be897d54bb34c513091 202 Pfam PF01949 Protein of unknown function DUF99 15 195 6.9E-64 T 23-10-2018 IPR002802 Protein of unknown function DUF99 TON_1492 3ff3026ee75d2be897d54bb34c513091 202 Hamap MF_00582 UPF0215 protein . 16 196 33.749 T 23-10-2018 IPR002802 Protein of unknown function DUF99 TON_0174 6f40833d6f1ecf7d5a6a9665ab298837 329 Pfam PF16868 NMT1-like family 38 320 1.5E-86 T 23-10-2018 IPR011852 TRAP transporter solute receptor, TAXI family TON_0174 6f40833d6f1ecf7d5a6a9665ab298837 329 Gene3D G3DSA:3.40.190.10 120 257 4.2E-102 T 23-10-2018 TON_0174 6f40833d6f1ecf7d5a6a9665ab298837 329 TIGRFAM TIGR02122 TRAP_TAXI: TRAP transporter solute receptor, TAXI family 1 320 9.5E-104 T 23-10-2018 IPR011852 TRAP transporter solute receptor, TAXI family TON_0174 6f40833d6f1ecf7d5a6a9665ab298837 329 SUPERFAMILY SSF53850 34 321 3.22E-78 T 23-10-2018 TON_0174 6f40833d6f1ecf7d5a6a9665ab298837 329 Gene3D G3DSA:3.40.190.10 38 320 4.2E-102 T 23-10-2018 TON_1697 7639a2e3d1f2b6caff4199b0d43705b8 363 SUPERFAMILY SSF53756 21 359 6.8E-36 T 23-10-2018 TON_1697 7639a2e3d1f2b6caff4199b0d43705b8 363 Gene3D G3DSA:3.40.50.2000 16 186 9.3E-19 T 23-10-2018 TON_1697 7639a2e3d1f2b6caff4199b0d43705b8 363 Gene3D G3DSA:3.40.50.2000 187 341 2.4E-12 T 23-10-2018 TON_1697 7639a2e3d1f2b6caff4199b0d43705b8 363 Pfam PF13439 Glycosyltransferase Family 4 18 180 7.4E-15 T 23-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 TON_1665 2435e2589b2860852ebc2d4442af005a 469 Pfam PF13380 CoA binding domain 13 139 1.8E-21 T 23-10-2018 IPR003781 CoA-binding GO:0048037 TON_1665 2435e2589b2860852ebc2d4442af005a 469 SUPERFAMILY SSF52210 305 463 5.89E-35 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TON_1665 2435e2589b2860852ebc2d4442af005a 469 Gene3D G3DSA:3.40.50.261 136 300 8.5E-61 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TON_1665 2435e2589b2860852ebc2d4442af005a 469 Gene3D G3DSA:3.40.50.261 302 466 1.7E-44 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TON_1665 2435e2589b2860852ebc2d4442af005a 469 SUPERFAMILY SSF52210 136 298 3.53E-43 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TON_1665 2435e2589b2860852ebc2d4442af005a 469 Gene3D G3DSA:3.40.50.720 4 134 9.9E-42 T 23-10-2018 TON_1665 2435e2589b2860852ebc2d4442af005a 469 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 160 297 5.0E-58 T 23-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain TON_1665 2435e2589b2860852ebc2d4442af005a 469 SUPERFAMILY SSF51735 6 135 9.18E-35 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TON_1665 2435e2589b2860852ebc2d4442af005a 469 SMART SM00881 9 107 4.4E-36 T 23-10-2018 IPR003781 CoA-binding GO:0048037 TON_1795 6b434df663ac63a17e42cef09bcf53d9 439 SUPERFAMILY SSF53850 62 433 6.73E-91 T 23-10-2018 TON_1795 6b434df663ac63a17e42cef09bcf53d9 439 ProSitePatterns PS01037 Bacterial extracellular solute-binding proteins, family 1 signature. 170 187 - T 23-10-2018 IPR006061 Solute-binding family 1, conserved site GO:0055085 TON_1795 6b434df663ac63a17e42cef09bcf53d9 439 Gene3D G3DSA:3.40.190.10 68 394 9.5E-137 T 23-10-2018 TON_1795 6b434df663ac63a17e42cef09bcf53d9 439 PRINTS PR00181 Maltose binding protein signature 188 207 2.6E-13 T 23-10-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0008643|GO:0015144 TON_1795 6b434df663ac63a17e42cef09bcf53d9 439 PRINTS PR00181 Maltose binding protein signature 265 284 2.6E-13 T 23-10-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0008643|GO:0015144 TON_1795 6b434df663ac63a17e42cef09bcf53d9 439 PRINTS PR00181 Maltose binding protein signature 167 186 2.6E-13 T 23-10-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0008643|GO:0015144 TON_1795 6b434df663ac63a17e42cef09bcf53d9 439 PRINTS PR00181 Maltose binding protein signature 394 413 2.6E-13 T 23-10-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0008643|GO:0015144 TON_1795 6b434df663ac63a17e42cef09bcf53d9 439 PRINTS PR00181 Maltose binding protein signature 105 123 2.6E-13 T 23-10-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0008643|GO:0015144 TON_1795 6b434df663ac63a17e42cef09bcf53d9 439 Pfam PF13416 Bacterial extracellular solute-binding protein 83 378 2.8E-51 T 23-10-2018 IPR006059 Bacterial extracellular solute-binding protein TON_1795 6b434df663ac63a17e42cef09bcf53d9 439 Gene3D G3DSA:3.40.190.10 175 409 9.5E-137 T 23-10-2018 TON_0121 6f3dbd3e58c666efa0e991741abf8b2e 166 Pfam PF03692 Putative zinc- or iron-chelating domain 25 130 2.4E-18 T 23-10-2018 IPR005358 Putative zinc- or iron-chelating domain containing protein TON_1412 c9b927f38bfbc565fa3a2fe483a870e6 337 SUPERFAMILY SSF53335 87 335 6.66E-46 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TON_1412 c9b927f38bfbc565fa3a2fe483a870e6 337 Gene3D G3DSA:3.40.50.150 150 337 4.0E-35 T 23-10-2018 TON_1412 c9b927f38bfbc565fa3a2fe483a870e6 337 Pfam PF02475 Met-10+ like-protein 89 266 2.4E-36 T 23-10-2018 IPR030382 SAM-dependent methyltransferase TRM5/TYW2-type Reactome: R-HSA-6782861 TON_1412 c9b927f38bfbc565fa3a2fe483a870e6 337 Gene3D G3DSA:3.30.300.110 64 146 9.9E-13 T 23-10-2018 TON_0253 cf20d3eb5cf416648beca53052ca271b 319 Pfam PF13424 Tetratricopeptide repeat 83 153 1.3E-9 T 23-10-2018 TON_0253 cf20d3eb5cf416648beca53052ca271b 319 SMART SM00028 81 114 19.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TON_0253 cf20d3eb5cf416648beca53052ca271b 319 SMART SM00028 121 154 0.0017 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TON_0253 cf20d3eb5cf416648beca53052ca271b 319 Gene3D G3DSA:1.25.40.10 30 237 4.2E-15 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TON_0253 cf20d3eb5cf416648beca53052ca271b 319 SUPERFAMILY SSF48452 76 219 1.16E-13 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TON_0147 1af1e1d605e20227178292131feb0c38 443 PIRSF PIRSF001413 6 430 5.6E-159 T 23-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 TON_0147 1af1e1d605e20227178292131feb0c38 443 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 18 424 42.611 T 23-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 TON_0147 1af1e1d605e20227178292131feb0c38 443 Gene3D G3DSA:3.40.50.1100 11 236 2.3E-178 T 23-10-2018 TON_0147 1af1e1d605e20227178292131feb0c38 443 Gene3D G3DSA:3.40.50.1100 10 417 2.3E-178 T 23-10-2018 TON_0147 1af1e1d605e20227178292131feb0c38 443 PIRSF PIRSF500824 1 433 4.0E-216 T 23-10-2018 IPR006316 Tryptophan synthase, beta chain-like GO:0000162|GO:0004834|GO:0030170 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 TON_0147 1af1e1d605e20227178292131feb0c38 443 SUPERFAMILY SSF53686 24 422 1.57E-111 T 23-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme TON_0147 1af1e1d605e20227178292131feb0c38 443 TIGRFAM TIGR01415 trpB_rel: pyridoxal-phosphate dependent TrpB-like enzyme 10 427 6.3E-223 T 23-10-2018 IPR006316 Tryptophan synthase, beta chain-like GO:0000162|GO:0004834|GO:0030170 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 TON_0147 1af1e1d605e20227178292131feb0c38 443 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 103 117 - T 23-10-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 TON_0147 1af1e1d605e20227178292131feb0c38 443 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 75 411 2.8E-47 T 23-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme TON_0265 f7fcd8287742083519ec5fcb3c3b18a5 146 Gene3D G3DSA:3.30.460.10 3 117 5.7E-8 T 23-10-2018 TON_0265 f7fcd8287742083519ec5fcb3c3b18a5 146 SUPERFAMILY SSF81301 5 117 9.16E-8 T 23-10-2018 TON_1612 cf7670467139a4a2e72d5fa3cca5dda5 301 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 94 105 - T 23-10-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TON_1612 cf7670467139a4a2e72d5fa3cca5dda5 301 Gene3D G3DSA:3.20.20.70 91 298 8.5E-51 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TON_1612 cf7670467139a4a2e72d5fa3cca5dda5 301 Pfam PF04055 Radical SAM superfamily 92 256 5.6E-15 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TON_1612 cf7670467139a4a2e72d5fa3cca5dda5 301 Pfam PF13353 4Fe-4S single cluster domain 96 207 9.3E-12 T 23-10-2018 TON_1612 cf7670467139a4a2e72d5fa3cca5dda5 301 SUPERFAMILY SSF102114 92 278 7.59E-31 T 23-10-2018 TON_0404 af288e6120dd0aa0feecf5540f8499cf 125 SUPERFAMILY SSF46785 24 123 1.66E-35 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TON_0404 af288e6120dd0aa0feecf5540f8499cf 125 Gene3D G3DSA:2.20.28.10 28 125 2.1E-33 T 23-10-2018 TON_1281 00539fe4282d4e005852008738e4db3f 386 Pfam PF01266 FAD dependent oxidoreductase 12 355 1.5E-73 T 23-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 TON_1281 00539fe4282d4e005852008738e4db3f 386 SUPERFAMILY SSF54373 224 316 1.7E-9 T 23-10-2018 TON_1281 00539fe4282d4e005852008738e4db3f 386 Gene3D G3DSA:3.50.50.60 12 359 1.9E-142 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TON_1281 00539fe4282d4e005852008738e4db3f 386 SUPERFAMILY SSF51905 11 376 2.46E-61 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TON_1281 00539fe4282d4e005852008738e4db3f 386 Gene3D G3DSA:3.30.9.10 88 315 1.9E-142 T 23-10-2018 TON_0438 6c630972ae114e342618514b3ef8eb23 218 SUPERFAMILY SSF55021 144 214 6.27E-9 T 23-10-2018 TON_0438 6c630972ae114e342618514b3ef8eb23 218 Gene3D G3DSA:3.30.2130.10 82 216 6.8E-10 T 23-10-2018 TON_0438 6c630972ae114e342618514b3ef8eb23 218 Pfam PF13840 ACT domain 151 212 7.5E-13 T 23-10-2018 IPR027795 CASTOR, ACT domain TON_0438 6c630972ae114e342618514b3ef8eb23 218 PIRSF PIRSF014439 1 218 3.8E-74 T 23-10-2018 IPR016619 Uncharacterised conserved protein UCP014439, ACT TON_1562 d40cfcd6504714ad335ed5d717b76e2a 252 Hamap MF_00187 Sulfur carrier protein FdhD [fdhD]. 1 251 26.519 T 23-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 TON_1562 d40cfcd6504714ad335ed5d717b76e2a 252 Pfam PF02634 FdhD/NarQ family 36 250 3.8E-58 T 23-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 TON_1562 d40cfcd6504714ad335ed5d717b76e2a 252 Gene3D G3DSA:3.40.140.10 107 252 1.9E-46 T 23-10-2018 TON_1562 d40cfcd6504714ad335ed5d717b76e2a 252 SUPERFAMILY SSF53927 7 250 2.29E-58 T 23-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 TON_1562 d40cfcd6504714ad335ed5d717b76e2a 252 TIGRFAM TIGR00129 fdhD_narQ: formate dehydrogenase family accessory protein FdhD 38 250 5.4E-56 T 23-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 TON_1562 d40cfcd6504714ad335ed5d717b76e2a 252 PIRSF PIRSF015626 2 252 1.1E-61 T 23-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 TON_1453 3f78538c0b2d61300bbdeeb14d449e81 431 SUPERFAMILY SSF111283 1 425 2.88E-85 T 23-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 TON_1453 3f78538c0b2d61300bbdeeb14d449e81 431 Gene3D G3DSA:3.30.2290.10 1 210 5.9E-23 T 23-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal TON_1453 3f78538c0b2d61300bbdeeb14d449e81 431 Pfam PF01523 Putative modulator of DNA gyrase 15 306 3.8E-49 T 23-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 TON_1032 a64192b54705721bce7c18443a9051fc 348 Pfam PF05343 M42 glutamyl aminopeptidase 45 335 3.4E-111 T 23-10-2018 IPR008007 Peptidase M42 TON_1032 a64192b54705721bce7c18443a9051fc 348 SUPERFAMILY SSF101821 68 177 8.24E-30 T 23-10-2018 TON_1032 a64192b54705721bce7c18443a9051fc 348 Gene3D G3DSA:2.40.30.40 68 161 6.2E-136 T 23-10-2018 IPR023367 Peptidase M42, domain 2 TON_1032 a64192b54705721bce7c18443a9051fc 348 Gene3D G3DSA:3.40.630.10 6 336 6.2E-136 T 23-10-2018 TON_1032 a64192b54705721bce7c18443a9051fc 348 PIRSF PIRSF001123 1 347 6.0E-122 T 23-10-2018 IPR008007 Peptidase M42 TON_1032 a64192b54705721bce7c18443a9051fc 348 SUPERFAMILY SSF53187 5 343 9.98E-70 T 23-10-2018 TON_0133 799c77efd13780f496176edfe12c0ee4 334 SUPERFAMILY SSF54211 3 180 6.07E-46 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TON_0133 799c77efd13780f496176edfe12c0ee4 334 SUPERFAMILY SSF55060 183 329 8.28E-37 T 23-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily TON_0133 799c77efd13780f496176edfe12c0ee4 334 Pfam PF08544 GHMP kinases C terminal 245 310 2.3E-13 T 23-10-2018 IPR013750 GHMP kinase, C-terminal domain TON_0133 799c77efd13780f496176edfe12c0ee4 334 Hamap MF_00217 Mevalonate kinase [mvk]. 3 327 59.122 T 23-10-2018 IPR022937 Mevalonate kinase, archaeal GO:0004496 KEGG: 00900+2.7.1.36|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-922 TON_0133 799c77efd13780f496176edfe12c0ee4 334 PRINTS PR00959 Mevalonate kinase family signature 150 169 6.0E-29 T 23-10-2018 TON_0133 799c77efd13780f496176edfe12c0ee4 334 PRINTS PR00959 Mevalonate kinase family signature 107 129 6.0E-29 T 23-10-2018 TON_0133 799c77efd13780f496176edfe12c0ee4 334 PRINTS PR00959 Mevalonate kinase family signature 7 31 6.0E-29 T 23-10-2018 TON_0133 799c77efd13780f496176edfe12c0ee4 334 PRINTS PR00959 Mevalonate kinase family signature 283 300 6.0E-29 T 23-10-2018 TON_0133 799c77efd13780f496176edfe12c0ee4 334 TIGRFAM TIGR00549 mevalon_kin: mevalonate kinase 7 298 3.6E-86 T 23-10-2018 IPR006205 Mevalonate kinase GO:0004496|GO:0005524|GO:0005737|GO:0008299 KEGG: 00900+2.7.1.36|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-2426168 TON_0133 799c77efd13780f496176edfe12c0ee4 334 Gene3D G3DSA:3.30.70.890 187 319 3.7E-41 T 23-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily TON_0133 799c77efd13780f496176edfe12c0ee4 334 Gene3D G3DSA:3.30.230.10 1 182 1.4E-50 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TON_0133 799c77efd13780f496176edfe12c0ee4 334 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 109 120 - T 23-10-2018 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 TON_0133 799c77efd13780f496176edfe12c0ee4 334 Pfam PF00288 GHMP kinases N terminal domain 103 169 6.6E-17 T 23-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 TON_1580 28df4a4efa352b40bfff448a8eaaff4f 522 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 167 191 2.8E-6 T 23-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_1580 28df4a4efa352b40bfff448a8eaaff4f 522 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 136 155 2.8E-6 T 23-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_1580 28df4a4efa352b40bfff448a8eaaff4f 522 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 249 273 2.8E-6 T 23-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_1580 28df4a4efa352b40bfff448a8eaaff4f 522 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 397 423 2.8E-6 T 23-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_1580 28df4a4efa352b40bfff448a8eaaff4f 522 Pfam PF00361 Proton-conducting membrane transporter 132 439 5.3E-59 T 23-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_1580 28df4a4efa352b40bfff448a8eaaff4f 522 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 74 115 2.3E-6 T 23-10-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_0006 c25f59aa0818e1bb24d1fd586ffb46b5 392 Gene3D G3DSA:1.20.1250.20 7 208 1.2E-28 T 23-10-2018 TON_0006 c25f59aa0818e1bb24d1fd586ffb46b5 392 SUPERFAMILY SSF103473 11 384 1.14E-56 T 23-10-2018 IPR036259 MFS transporter superfamily TON_0006 c25f59aa0818e1bb24d1fd586ffb46b5 392 Gene3D G3DSA:1.20.1250.20 209 386 1.1E-20 T 23-10-2018 TON_0006 c25f59aa0818e1bb24d1fd586ffb46b5 392 Pfam PF07690 Major Facilitator Superfamily 20 338 8.8E-34 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TON_0742 543da2dc41ce0363a44301468898531b 296 Gene3D G3DSA:3.40.50.300 92 292 5.6E-9 T 23-10-2018 TON_0742 543da2dc41ce0363a44301468898531b 296 Hamap MF_00769 2-phosphoglycerate kinase [pgk2]. 5 294 44.801 T 23-10-2018 IPR020872 2-phosphoglycerate kinase GO:0016774 TON_0742 543da2dc41ce0363a44301468898531b 296 SUPERFAMILY SSF52540 91 283 1.18E-10 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_0742 543da2dc41ce0363a44301468898531b 296 Pfam PF03477 ATP cone domain 13 86 1.3E-10 T 23-10-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 TON_0340 d0770e959fabaef3f3b5c3e02921c155 268 Pfam PF14336 Domain of unknown function (DUF4392) 3 260 3.8E-65 T 23-10-2018 IPR025504 Domain of unknown function DUF4392 KEGG: 00471+4.2.1.48 TON_0340 d0770e959fabaef3f3b5c3e02921c155 268 Gene3D G3DSA:3.90.1640.20 1 268 2.7E-109 T 23-10-2018 TON_1881 64f03f7eb3c3d41d8439d820780a5990 195 Hamap MF_00266 tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase [taw3]. 9 195 31.43 T 23-10-2018 IPR022908 tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase GO:0008175|GO:0030488|GO:0031591 MetaCyc: PWY-7286 TON_1881 64f03f7eb3c3d41d8439d820780a5990 195 Pfam PF02676 Methyltransferase TYW3 11 193 2.3E-47 T 23-10-2018 IPR003827 tRNA wybutosine-synthesizing protein MetaCyc: PWY-7286|Reactome: R-HSA-6782861 TON_1881 64f03f7eb3c3d41d8439d820780a5990 195 SUPERFAMILY SSF111278 7 192 7.32E-62 T 23-10-2018 IPR036602 tRNA wybutosine-synthesizing-like superfamily MetaCyc: PWY-7286|Reactome: R-HSA-6782861 TON_1881 64f03f7eb3c3d41d8439d820780a5990 195 Gene3D G3DSA:3.30.1960.10 2 195 3.6E-70 T 23-10-2018 IPR036602 tRNA wybutosine-synthesizing-like superfamily MetaCyc: PWY-7286|Reactome: R-HSA-6782861 TON_1918 399207330ad2653acfb2518640246c5d 352 Pfam PF00535 Glycosyl transferase family 2 4 168 1.0E-38 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TON_1918 399207330ad2653acfb2518640246c5d 352 SUPERFAMILY SSF53448 1 258 3.44E-47 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TON_1918 399207330ad2653acfb2518640246c5d 352 Pfam PF04138 GtrA-like protein 236 351 7.9E-26 T 23-10-2018 IPR007267 GtrA-like protein GO:0000271|GO:0016021 TON_1918 399207330ad2653acfb2518640246c5d 352 Gene3D G3DSA:3.90.550.10 1 239 1.0E-52 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TON_1259 ec1de31f855aea9c9012df5733d0dbb0 392 Pfam PF00155 Aminotransferase class I and II 34 384 2.0E-76 T 23-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 TON_1259 ec1de31f855aea9c9012df5733d0dbb0 392 Gene3D G3DSA:3.40.640.10 65 284 4.1E-133 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TON_1259 ec1de31f855aea9c9012df5733d0dbb0 392 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 234 247 - T 23-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 TON_1259 ec1de31f855aea9c9012df5733d0dbb0 392 Gene3D G3DSA:3.90.1150.10 34 384 4.1E-133 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TON_1259 ec1de31f855aea9c9012df5733d0dbb0 392 SUPERFAMILY SSF53383 10 391 3.5E-123 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TON_1606 e23885faca539a860545493c818210b2 199 Pfam PF07155 ECF-type riboflavin transporter, S component 38 190 2.1E-38 T 23-10-2018 IPR009825 ECF transporter, substrate-specific component-like GO:0016020 TON_1606 e23885faca539a860545493c818210b2 199 Gene3D G3DSA:1.10.1760.20 33 194 5.3E-46 T 23-10-2018 TON_0929 75df1a607d28a420e69d2b25b1d059d0 451 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 6 438 9.4E-187 T 23-10-2018 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TON_0929 75df1a607d28a420e69d2b25b1d059d0 451 SMART SM00998 360 439 1.1E-27 T 23-10-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TON_0929 75df1a607d28a420e69d2b25b1d059d0 451 Gene3D G3DSA:1.10.40.30 360 439 2.3E-21 T 23-10-2018 TON_0929 75df1a607d28a420e69d2b25b1d059d0 451 ProSitePatterns PS00163 Fumarate lyases signature. 272 281 - T 23-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 TON_0929 75df1a607d28a420e69d2b25b1d059d0 451 Pfam PF10397 Adenylosuccinate lyase C-terminus 362 438 2.0E-17 T 23-10-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TON_0929 75df1a607d28a420e69d2b25b1d059d0 451 Gene3D G3DSA:1.20.200.10 101 359 1.1E-96 T 23-10-2018 TON_0929 75df1a607d28a420e69d2b25b1d059d0 451 Gene3D G3DSA:1.10.275.10 1 100 6.8E-38 T 23-10-2018 IPR024083 Fumarase/histidase, N-terminal TON_0929 75df1a607d28a420e69d2b25b1d059d0 451 SUPERFAMILY SSF48557 4 441 5.03E-135 T 23-10-2018 IPR008948 L-Aspartase-like GO:0003824 TON_0929 75df1a607d28a420e69d2b25b1d059d0 451 PRINTS PR00145 Argininosuccinate lyase family signature 272 288 5.5E-12 T 23-10-2018 TON_0929 75df1a607d28a420e69d2b25b1d059d0 451 PRINTS PR00145 Argininosuccinate lyase family signature 136 156 5.5E-12 T 23-10-2018 TON_0929 75df1a607d28a420e69d2b25b1d059d0 451 PRINTS PR00145 Argininosuccinate lyase family signature 227 251 5.5E-12 T 23-10-2018 TON_0929 75df1a607d28a420e69d2b25b1d059d0 451 PRINTS PR00145 Argininosuccinate lyase family signature 95 117 5.5E-12 T 23-10-2018 TON_0929 75df1a607d28a420e69d2b25b1d059d0 451 PRINTS PR00149 Fumarate lyase superfamily signature 227 254 2.4E-27 T 23-10-2018 IPR000362 Fumarate lyase family TON_0929 75df1a607d28a420e69d2b25b1d059d0 451 PRINTS PR00149 Fumarate lyase superfamily signature 141 159 2.4E-27 T 23-10-2018 IPR000362 Fumarate lyase family TON_0929 75df1a607d28a420e69d2b25b1d059d0 451 PRINTS PR00149 Fumarate lyase superfamily signature 96 114 2.4E-27 T 23-10-2018 IPR000362 Fumarate lyase family TON_0929 75df1a607d28a420e69d2b25b1d059d0 451 PRINTS PR00149 Fumarate lyase superfamily signature 272 288 2.4E-27 T 23-10-2018 IPR000362 Fumarate lyase family TON_0929 75df1a607d28a420e69d2b25b1d059d0 451 Pfam PF00206 Lyase 13 293 3.7E-58 T 23-10-2018 IPR022761 Fumarate lyase, N-terminal TON_0869 1589bf37397767a0eca65c247a440105 119 SUPERFAMILY SSF117916 16 59 1.05E-5 T 23-10-2018 IPR034904 Fe-S cluster assembly domain superfamily TON_0869 1589bf37397767a0eca65c247a440105 119 Pfam PF01883 Iron-sulfur cluster assembly protein 17 56 6.8E-6 T 23-10-2018 IPR002744 MIP18 family-like TON_0858 dd7de4bd41faed65c8bce7ab9334597e 431 SUPERFAMILY SSF52833 30 169 1.08E-8 T 23-10-2018 IPR036249 Thioredoxin-like superfamily TON_0858 dd7de4bd41faed65c8bce7ab9334597e 431 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 207 413 4.1E-10 T 23-10-2018 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 TON_0858 dd7de4bd41faed65c8bce7ab9334597e 431 Gene3D G3DSA:3.40.30.10 22 173 5.6E-9 T 23-10-2018 TON_1047 f798d5385bc18060a4d2a363abb2a506 343 Gene3D G3DSA:3.40.50.1970 1 152 7.7E-33 T 23-10-2018 TON_1047 f798d5385bc18060a4d2a363abb2a506 343 PIRSF PIRSF000112 1 340 6.0E-65 T 23-10-2018 IPR016205 Glycerol dehydrogenase GO:0016614|GO:0046872|GO:0055114 KEGG: 00564+1.1.1.261|MetaCyc: PWY-6349 TON_1047 f798d5385bc18060a4d2a363abb2a506 343 Hamap MF_00497_A Glycerol-1-phosphate dehydrogenase [NAD(P)+] [egsA]. 1 343 45.607 T 23-10-2018 IPR023002 Glycerol-1-phosphate dehydrogenase, archaea GO:0050492|GO:0055114 KEGG: 00564+1.1.1.261|MetaCyc: PWY-6349 TON_1047 f798d5385bc18060a4d2a363abb2a506 343 Gene3D G3DSA:1.20.1090.10 153 342 5.2E-65 T 23-10-2018 TON_1047 f798d5385bc18060a4d2a363abb2a506 343 Pfam PF13685 Iron-containing alcohol dehydrogenase 10 265 4.5E-72 T 23-10-2018 IPR032837 Glycerol-1-phosphate dehydrogenase KEGG: 00564+1.1.1.261|MetaCyc: PWY-6349 TON_1047 f798d5385bc18060a4d2a363abb2a506 343 SUPERFAMILY SSF56796 2 336 5.1E-72 T 23-10-2018 TON_0660 6fa7b2f3ba9cac1d253cfc741f30830c 267 SUPERFAMILY SSF143597 92 260 4.97E-29 T 23-10-2018 IPR036888 DNA integrity scanning protein, DisA, N-terminal domain superfamily TON_0660 6fa7b2f3ba9cac1d253cfc741f30830c 267 Hamap MF_00840 Diadenylate cyclase [dacZ]. 8 266 34.469 T 23-10-2018 IPR014499 Diadenylate cyclase, DacZ-type TON_0660 6fa7b2f3ba9cac1d253cfc741f30830c 267 PIRSF PIRSF019073 4 267 1.7E-76 T 23-10-2018 IPR014499 Diadenylate cyclase, DacZ-type TON_0660 6fa7b2f3ba9cac1d253cfc741f30830c 267 Gene3D G3DSA:3.40.1700.10 169 265 3.3E-13 T 23-10-2018 IPR036888 DNA integrity scanning protein, DisA, N-terminal domain superfamily TON_0660 6fa7b2f3ba9cac1d253cfc741f30830c 267 Pfam PF02457 DisA bacterial checkpoint controller nucleotide-binding 133 255 5.9E-21 T 23-10-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal TON_1337 e6975f3ed030e6a97b348b19ce9457e3 288 SUPERFAMILY SSF52343 89 256 1.19E-15 T 23-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain TON_1337 e6975f3ed030e6a97b348b19ce9457e3 288 PIRSF PIRSF006816 1 263 9.7E-65 T 23-10-2018 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 TON_1337 e6975f3ed030e6a97b348b19ce9457e3 288 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 221 256 6.8E-12 T 23-10-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain TON_1337 e6975f3ed030e6a97b348b19ce9457e3 288 Gene3D G3DSA:2.40.30.10 1 92 2.8E-16 T 23-10-2018 TON_1337 e6975f3ed030e6a97b348b19ce9457e3 288 SUPERFAMILY SSF63380 2 93 7.94E-16 T 23-10-2018 IPR017938 Riboflavin synthase-like beta-barrel TON_1337 e6975f3ed030e6a97b348b19ce9457e3 288 Gene3D G3DSA:3.40.50.80 100 211 6.5E-24 T 23-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain TON_1030 63b6e1b0f3c3396388d7d291c9af5f7e 161 PIRSF PIRSF019239 1 161 1.6E-39 T 23-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 TON_1030 63b6e1b0f3c3396388d7d291c9af5f7e 161 Pfam PF01899 Na+/H+ ion antiporter subunit 10 159 2.8E-37 T 23-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 TON_0199 5c2de3feffa45ce1bdca57b10977cbe0 441 Gene3D G3DSA:1.20.1250.20 224 425 1.2E-23 T 23-10-2018 TON_0199 5c2de3feffa45ce1bdca57b10977cbe0 441 SUPERFAMILY SSF103473 6 424 1.28E-63 T 23-10-2018 IPR036259 MFS transporter superfamily TON_0199 5c2de3feffa45ce1bdca57b10977cbe0 441 Pfam PF07690 Major Facilitator Superfamily 13 274 6.0E-35 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TON_0199 5c2de3feffa45ce1bdca57b10977cbe0 441 Gene3D G3DSA:1.20.1250.20 4 197 8.7E-30 T 23-10-2018 TON_1673 92d1876b3911fe0add9f0ddad36ab72b 476 Pfam PF04415 Protein of unknown function (DUF515) 30 475 6.1E-143 T 23-10-2018 IPR007509 Protein of unknown function DUF515 TON_1457 255908dc5b33632e3f389c6758920706 149 Pfam PF00582 Universal stress protein family 2 149 1.0E-20 T 23-10-2018 IPR006016 UspA TON_1457 255908dc5b33632e3f389c6758920706 149 Gene3D G3DSA:3.40.50.620 1 149 7.8E-31 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TON_1457 255908dc5b33632e3f389c6758920706 149 SUPERFAMILY SSF52402 2 149 7.53E-26 T 23-10-2018 TON_1315 c71f16249c699d7e9e3d4bd3c36da933 332 Pfam PF04122 Putative cell wall binding repeat 2 112 190 1.7E-7 T 23-10-2018 IPR007253 Putative cell wall binding repeat 2 TON_1315 c71f16249c699d7e9e3d4bd3c36da933 332 SUPERFAMILY SSF46785 264 328 2.73E-10 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TON_1315 c71f16249c699d7e9e3d4bd3c36da933 332 Gene3D G3DSA:1.10.10.10 264 328 1.1E-9 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TON_0749 87fae794a12487c5a905b4cccaf1f702 621 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 8 206 3.1E-77 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 TON_0749 87fae794a12487c5a905b4cccaf1f702 621 SMART SM00790 6 207 1.8E-118 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 TON_0749 87fae794a12487c5a905b4cccaf1f702 621 Gene3D G3DSA:1.10.599.10 239 607 4.2E-132 T 23-10-2018 IPR013985 Aldehyde ferredoxin oxidoreductase, domain 3 GO:0016625|GO:0051536|GO:0055114 KEGG: 00030+1.2.7.5 TON_0749 87fae794a12487c5a905b4cccaf1f702 621 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 220 607 1.6E-110 T 23-10-2018 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 TON_0749 87fae794a12487c5a905b4cccaf1f702 621 SUPERFAMILY SSF56228 3 211 3.4E-73 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily TON_0749 87fae794a12487c5a905b4cccaf1f702 621 SUPERFAMILY SSF48310 213 620 5.23E-127 T 23-10-2018 IPR036021 Aldehyde ferredoxin oxidoreductase-like, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 TON_0749 87fae794a12487c5a905b4cccaf1f702 621 Gene3D G3DSA:3.60.9.10 3 211 1.3E-89 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily TON_0749 87fae794a12487c5a905b4cccaf1f702 621 Gene3D G3DSA:1.10.569.10 241 419 4.2E-132 T 23-10-2018 IPR013984 Aldehyde ferredoxin oxidoreductase, domain 2 TON_1437 3f3314de87241de305a0a4bf805d33d0 310 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 154 302 4.0E-30 T 23-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 TON_1437 3f3314de87241de305a0a4bf805d33d0 310 PRINTS PR00101 Aspartate carbamoyltransferase signature 286 300 2.6E-38 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TON_1437 3f3314de87241de305a0a4bf805d33d0 310 PRINTS PR00101 Aspartate carbamoyltransferase signature 225 234 2.6E-38 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TON_1437 3f3314de87241de305a0a4bf805d33d0 310 PRINTS PR00101 Aspartate carbamoyltransferase signature 41 63 2.6E-38 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TON_1437 3f3314de87241de305a0a4bf805d33d0 310 PRINTS PR00101 Aspartate carbamoyltransferase signature 80 89 2.6E-38 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TON_1437 3f3314de87241de305a0a4bf805d33d0 310 PRINTS PR00101 Aspartate carbamoyltransferase signature 134 151 2.6E-38 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TON_1437 3f3314de87241de305a0a4bf805d33d0 310 PRINTS PR00101 Aspartate carbamoyltransferase signature 264 269 2.6E-38 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TON_1437 3f3314de87241de305a0a4bf805d33d0 310 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 6 304 2.2E-132 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TON_1437 3f3314de87241de305a0a4bf805d33d0 310 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 135 146 3.7E-24 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TON_1437 3f3314de87241de305a0a4bf805d33d0 310 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 270 293 3.7E-24 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TON_1437 3f3314de87241de305a0a4bf805d33d0 310 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 260 269 3.7E-24 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TON_1437 3f3314de87241de305a0a4bf805d33d0 310 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 51 70 3.7E-24 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TON_1437 3f3314de87241de305a0a4bf805d33d0 310 Gene3D G3DSA:3.40.50.1370 135 292 4.4E-124 T 23-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 TON_1437 3f3314de87241de305a0a4bf805d33d0 310 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 5 307 39.745 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TON_1437 3f3314de87241de305a0a4bf805d33d0 310 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 51 58 - T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TON_1437 3f3314de87241de305a0a4bf805d33d0 310 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 6 147 6.2E-50 T 23-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 TON_1437 3f3314de87241de305a0a4bf805d33d0 310 Gene3D G3DSA:3.40.50.1370 7 301 4.4E-124 T 23-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 TON_1437 3f3314de87241de305a0a4bf805d33d0 310 SUPERFAMILY SSF53671 2 306 4.98E-102 T 23-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 TON_1435 3a4038256ba28124e1dabea1ca321caf 97 Pfam PF04892 VanZ like family 30 90 1.5E-8 T 23-10-2018 IPR006976 VanZ-like TON_1435 3a4038256ba28124e1dabea1ca321caf 97 SUPERFAMILY SSF144091 3 94 1.57E-5 T 23-10-2018 TON_0811 f674ea890b0cfdec8dd7ae2110a6a293 177 SUPERFAMILY SSF46785 4 65 3.83E-12 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TON_0811 f674ea890b0cfdec8dd7ae2110a6a293 177 SUPERFAMILY SSF46785 71 169 6.61E-17 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TON_0811 f674ea890b0cfdec8dd7ae2110a6a293 177 SMART SM00418 75 153 5.9E-7 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TON_0811 f674ea890b0cfdec8dd7ae2110a6a293 177 SMART SM00418 4 74 0.049 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TON_0811 f674ea890b0cfdec8dd7ae2110a6a293 177 Pfam PF13412 Winged helix-turn-helix DNA-binding 6 53 8.3E-10 T 23-10-2018 TON_0811 f674ea890b0cfdec8dd7ae2110a6a293 177 Pfam PF13412 Winged helix-turn-helix DNA-binding 84 128 1.8E-13 T 23-10-2018 TON_0811 f674ea890b0cfdec8dd7ae2110a6a293 177 Gene3D G3DSA:1.10.10.10 6 76 1.0E-16 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TON_0811 f674ea890b0cfdec8dd7ae2110a6a293 177 Gene3D G3DSA:1.10.10.10 78 144 4.9E-16 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TON_1953 87dd563c88db44e6cccd04633da5571f 125 SUPERFAMILY SSF50249 24 89 4.37E-5 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold TON_1137 0d144546a0fc203ac2a0854527956fdc 270 Pfam PF00288 GHMP kinases N terminal domain 75 144 9.1E-14 T 23-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 TON_1137 0d144546a0fc203ac2a0854527956fdc 270 Hamap MF_00370 Shikimate kinase [aroK]. 1 270 102.436 T 23-10-2018 IPR010189 Shikimate kinase, archaea GO:0004765|GO:0005737|GO:0009073 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 TON_1137 0d144546a0fc203ac2a0854527956fdc 270 Gene3D G3DSA:3.30.230.10 19 156 1.5E-20 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TON_1137 0d144546a0fc203ac2a0854527956fdc 270 PIRSF PIRSF005758 1 270 7.6E-91 T 23-10-2018 IPR010189 Shikimate kinase, archaea GO:0004765|GO:0005737|GO:0009073 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 TON_1137 0d144546a0fc203ac2a0854527956fdc 270 SUPERFAMILY SSF54211 18 154 2.5E-21 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TON_1137 0d144546a0fc203ac2a0854527956fdc 270 TIGRFAM TIGR01920 Shik_kin_archae: shikimate kinase 5 266 1.7E-87 T 23-10-2018 IPR010189 Shikimate kinase, archaea GO:0004765|GO:0005737|GO:0009073 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 TON_1599 da6246901b38712680e81c79a2638679 161 Gene3D G3DSA:3.30.2130.30 1 151 5.6E-18 T 23-10-2018 TON_1599 da6246901b38712680e81c79a2638679 161 SMART SM00981 63 150 8.9E-17 T 23-10-2018 IPR004114 THUMP domain GO:0003723 TON_1599 da6246901b38712680e81c79a2638679 161 SUPERFAMILY SSF143437 43 148 1.74E-17 T 23-10-2018 TON_1599 da6246901b38712680e81c79a2638679 161 Pfam PF02926 THUMP domain 28 149 2.3E-24 T 23-10-2018 IPR004114 THUMP domain GO:0003723 TON_1867 cae0338950d9222d9c49520839bd8784 335 Pfam PF01047 MarR family 22 71 6.4E-8 T 23-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TON_1867 cae0338950d9222d9c49520839bd8784 335 Gene3D G3DSA:1.10.10.10 10 95 2.2E-10 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TON_1867 cae0338950d9222d9c49520839bd8784 335 SUPERFAMILY SSF46785 20 73 4.65E-10 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TON_0137 721f57d92456f65861e05587af5c6d0e 342 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 210 222 - T 23-10-2018 IPR033749 Polyprenyl synthetase, conserved site TON_0137 721f57d92456f65861e05587af5c6d0e 342 Gene3D G3DSA:1.10.600.10 1 342 1.8E-136 T 23-10-2018 IPR008949 Isoprenoid synthase domain superfamily TON_0137 721f57d92456f65861e05587af5c6d0e 342 SUPERFAMILY SSF48576 3 341 2.28E-97 T 23-10-2018 IPR008949 Isoprenoid synthase domain superfamily TON_0137 721f57d92456f65861e05587af5c6d0e 342 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 83 97 - T 23-10-2018 IPR033749 Polyprenyl synthetase, conserved site TON_0137 721f57d92456f65861e05587af5c6d0e 342 Pfam PF00348 Polyprenyl synthetase 33 275 3.4E-71 T 23-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 TON_0169 c8e35bcf7dcb3925ee55083af73ca0d0 199 Hamap MF_01078 UPF0278 protein . 1 193 29.976 T 23-10-2018 IPR014856 PIN-domain ribonuclease TON_0169 c8e35bcf7dcb3925ee55083af73ca0d0 199 Pfam PF08745 PINc domain ribonuclease 2 190 7.2E-66 T 23-10-2018 IPR014856 PIN-domain ribonuclease TON_0169 c8e35bcf7dcb3925ee55083af73ca0d0 199 TIGRFAM TIGR03875 RNA_lig_partner: RNA ligase partner, MJ_0950 family 2 189 2.8E-70 T 23-10-2018 IPR014856 PIN-domain ribonuclease TON_0169 c8e35bcf7dcb3925ee55083af73ca0d0 199 SUPERFAMILY SSF88723 70 185 1.43E-7 T 23-10-2018 IPR029060 PIN-like domain superfamily TON_1442 1df1d130c913597f08164182a1946588 190 Gene3D G3DSA:3.40.50.300 1 189 3.7E-42 T 23-10-2018 TON_1442 1df1d130c913597f08164182a1946588 190 SUPERFAMILY SSF52540 1 188 2.34E-19 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_1442 1df1d130c913597f08164182a1946588 190 Pfam PF13238 AAA domain 3 138 4.3E-17 T 23-10-2018 TON_0748 58bbd60299f057ccbe969672aaabe1d9 279 Gene3D G3DSA:3.30.300.110 20 87 5.0E-29 T 23-10-2018 TON_0748 58bbd60299f057ccbe969672aaabe1d9 279 Pfam PF02475 Met-10+ like-protein 30 224 3.4E-69 T 23-10-2018 IPR030382 SAM-dependent methyltransferase TRM5/TYW2-type Reactome: R-HSA-6782861 TON_0748 58bbd60299f057ccbe969672aaabe1d9 279 SUPERFAMILY SSF53335 20 277 3.7E-71 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TON_0748 58bbd60299f057ccbe969672aaabe1d9 279 Hamap MF_01922 tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase [taw2]. 27 277 41.404 T 23-10-2018 IPR030867 tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase GO:0006400|GO:0016765 MetaCyc: PWY-7286 TON_0748 58bbd60299f057ccbe969672aaabe1d9 279 Gene3D G3DSA:3.40.50.150 88 279 9.0E-59 T 23-10-2018 TON_1361 5828724c36ff04710df39bdba607f84c 67 Gene3D G3DSA:3.30.70.20 2 67 1.0E-23 T 23-10-2018 TON_1361 5828724c36ff04710df39bdba607f84c 67 SUPERFAMILY SSF54862 3 65 1.96E-15 T 23-10-2018 TON_1361 5828724c36ff04710df39bdba607f84c 67 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 7 62 1.3E-18 T 23-10-2018 TON_1361 5828724c36ff04710df39bdba607f84c 67 PRINTS PR00352 3Fe-4S ferredoxin signature 18 28 1.1E-9 T 23-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 TON_1361 5828724c36ff04710df39bdba607f84c 67 PRINTS PR00352 3Fe-4S ferredoxin signature 50 62 1.1E-9 T 23-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 TON_1361 5828724c36ff04710df39bdba607f84c 67 PRINTS PR00352 3Fe-4S ferredoxin signature 7 18 1.1E-9 T 23-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 TON_1022 bd155da36b9dfc00fbe2e62d3b8c9b57 293 ProSitePatterns PS00668 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. 188 201 - T 23-10-2018 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_1022 bd155da36b9dfc00fbe2e62d3b8c9b57 293 Pfam PF00146 NADH dehydrogenase 9 288 4.3E-50 T 23-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_1238 5fae5a098cb7eb3660f0bed2cbb90968 103 SUPERFAMILY SSF50447 1 72 1.13E-17 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily TON_1238 5fae5a098cb7eb3660f0bed2cbb90968 103 Gene3D G3DSA:2.40.10.230 1 75 5.8E-25 T 23-10-2018 IPR038664 H/ACA RNP complex subunit Gar1/Naf1, Cbf5-binding domain TON_1238 5fae5a098cb7eb3660f0bed2cbb90968 103 Pfam PF04410 Gar1/Naf1 RNA binding region 2 75 5.2E-10 T 23-10-2018 IPR007504 H/ACA ribonucleoprotein complex, subunit Gar1/Naf1 GO:0001522|GO:0042254 TON_1238 5fae5a098cb7eb3660f0bed2cbb90968 103 ProDom PD064583 RNA-BINDING GAR1 COMPONENT RNP SNORNP HOMOLOG NUCLEOLAR PROCESSING RRNA VNG1366H 1 71 7.0E-27 T 23-10-2018 IPR020321 H/ACA ribonucleoprotein complex, subunit Gar1, archaea GO:0001522|GO:0042254 TON_0597 c88447a10428517e470fb9eee3aa2010 298 Pfam PF02653 Branched-chain amino acid transport system / permease component 11 278 1.2E-38 T 23-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TON_0930 22af3cbcbd39ffd4bef69b967e80fc94 91 Gene3D G3DSA:3.30.110.20 2 90 1.4E-38 T 23-10-2018 IPR036882 Alba-like domain superfamily GO:0003676 TON_0930 22af3cbcbd39ffd4bef69b967e80fc94 91 TIGRFAM TIGR00285 TIGR00285: DNA-binding protein Alba 4 90 4.7E-46 T 23-10-2018 IPR013795 DNA/RNA-binding protein Alba GO:0003677|GO:0003723|GO:0005737 TON_0930 22af3cbcbd39ffd4bef69b967e80fc94 91 Pfam PF01918 Alba 6 66 6.4E-22 T 23-10-2018 IPR002775 DNA/RNA-binding protein Alba-like GO:0003676 TON_0930 22af3cbcbd39ffd4bef69b967e80fc94 91 ProDom PD010497 ALBA DNA-BINDING DNA/RNA-BINDING RNA-BINDING ACETYLATION 3D-STRUCTURE DNA CONDENSATION AF1 SSO10B 8 90 2.0E-40 T 23-10-2018 TON_0930 22af3cbcbd39ffd4bef69b967e80fc94 91 SUPERFAMILY SSF82704 5 90 3.92E-27 T 23-10-2018 IPR036882 Alba-like domain superfamily GO:0003676 TON_0930 22af3cbcbd39ffd4bef69b967e80fc94 91 PIRSF PIRSF028732 1 91 2.5E-40 T 23-10-2018 IPR013795 DNA/RNA-binding protein Alba GO:0003677|GO:0003723|GO:0005737 TON_0930 22af3cbcbd39ffd4bef69b967e80fc94 91 Hamap MF_01122 DNA/RNA-binding protein Alba [albA]. 1 90 27.952 T 23-10-2018 IPR013795 DNA/RNA-binding protein Alba GO:0003677|GO:0003723|GO:0005737 TON_1388 35ada03264703886042ba9ab8e06ef48 311 Gene3D G3DSA:1.10.10.10 5 94 1.9E-16 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TON_1388 35ada03264703886042ba9ab8e06ef48 311 Pfam PF01163 RIO1 family 111 287 1.8E-47 T 23-10-2018 TON_1388 35ada03264703886042ba9ab8e06ef48 311 SMART SM00090 68 299 1.6E-81 T 23-10-2018 IPR000687 RIO kinase GO:0004674|GO:0005524 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6791226 TON_1388 35ada03264703886042ba9ab8e06ef48 311 Gene3D G3DSA:1.10.510.10 203 297 1.2E-15 T 23-10-2018 TON_1388 35ada03264703886042ba9ab8e06ef48 311 SUPERFAMILY SSF56112 103 273 2.46E-24 T 23-10-2018 IPR011009 Protein kinase-like domain superfamily TON_1388 35ada03264703886042ba9ab8e06ef48 311 Gene3D G3DSA:3.30.200.20 98 196 5.5E-24 T 23-10-2018 TON_1388 35ada03264703886042ba9ab8e06ef48 311 Pfam PF09202 Rio2, N-terminal 13 93 4.1E-23 T 23-10-2018 IPR015285 RIO2 kinase winged helix domain, N-terminal GO:0004674|GO:0005524|GO:0006468 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6791226 TON_1388 35ada03264703886042ba9ab8e06ef48 311 SUPERFAMILY SSF46785 8 94 2.28E-23 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TON_0834 4c27328eac4f07655502f73cb1c07a54 105 ProSitePatterns PS00194 Thioredoxin family active site. 19 37 - T 23-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 TON_0834 4c27328eac4f07655502f73cb1c07a54 105 SUPERFAMILY SSF52833 11 102 1.79E-24 T 23-10-2018 IPR036249 Thioredoxin-like superfamily TON_0834 4c27328eac4f07655502f73cb1c07a54 105 Gene3D G3DSA:3.40.30.10 9 100 4.3E-23 T 23-10-2018 TON_0834 4c27328eac4f07655502f73cb1c07a54 105 Pfam PF00085 Thioredoxin 14 97 5.0E-18 T 23-10-2018 IPR013766 Thioredoxin domain GO:0045454 TON_0450 9401d2dabea97d2a6c02f368fbbfa561 110 Pfam PF11419 Protein of unknown function (DUF3194) 15 97 5.0E-28 T 23-10-2018 IPR024502 Protein of unknown function DUF3194 TON_0450 9401d2dabea97d2a6c02f368fbbfa561 110 Gene3D G3DSA:3.30.300.100 1 110 1.2E-51 T 23-10-2018 IPR035954 MTH677-like superfamily TON_0450 9401d2dabea97d2a6c02f368fbbfa561 110 SUPERFAMILY SSF110783 15 98 5.62E-7 T 23-10-2018 IPR035954 MTH677-like superfamily TON_1634 15a3d984c266e1c378746b6fdd5180e0 325 Pfam PF00814 Glycoprotease family 23 292 9.5E-97 T 23-10-2018 IPR000905 Gcp-like domain TON_1634 15a3d984c266e1c378746b6fdd5180e0 325 Gene3D G3DSA:3.30.420.40 122 278 1.0E-114 T 23-10-2018 TON_1634 15a3d984c266e1c378746b6fdd5180e0 325 ProSitePatterns PS01016 Glycoprotease family signature. 92 112 - T 23-10-2018 IPR017860 Peptidase M22, conserved site Reactome: R-HSA-6782315 TON_1634 15a3d984c266e1c378746b6fdd5180e0 325 TIGRFAM TIGR03722 arch_KAE1: universal archaeal protein Kae1 4 324 1.1E-152 T 23-10-2018 IPR022449 tRNA N6-adenosine threonylcarbamoyltransferase Kae1, archaea GO:0000408|GO:0002949 TON_1634 15a3d984c266e1c378746b6fdd5180e0 325 SUPERFAMILY SSF53067 1 293 9.71E-38 T 23-10-2018 TON_1634 15a3d984c266e1c378746b6fdd5180e0 325 Gene3D G3DSA:3.30.420.40 4 298 1.0E-114 T 23-10-2018 TON_1634 15a3d984c266e1c378746b6fdd5180e0 325 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 93 112 8.1E-41 T 23-10-2018 IPR017861 Kae1/TsaD family TON_1634 15a3d984c266e1c378746b6fdd5180e0 325 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 124 136 8.1E-41 T 23-10-2018 IPR017861 Kae1/TsaD family TON_1634 15a3d984c266e1c378746b6fdd5180e0 325 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 146 167 8.1E-41 T 23-10-2018 IPR017861 Kae1/TsaD family TON_1634 15a3d984c266e1c378746b6fdd5180e0 325 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 72 92 8.1E-41 T 23-10-2018 IPR017861 Kae1/TsaD family TON_1634 15a3d984c266e1c378746b6fdd5180e0 325 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 4 17 8.1E-41 T 23-10-2018 IPR017861 Kae1/TsaD family TON_1634 15a3d984c266e1c378746b6fdd5180e0 325 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 248 257 8.1E-41 T 23-10-2018 IPR017861 Kae1/TsaD family TON_1634 15a3d984c266e1c378746b6fdd5180e0 325 Hamap MF_01446 tRNA N6-adenosine threonylcarbamoyltransferase [kae1]. 1 325 38.354 T 23-10-2018 IPR034680 tRNA N6-adenosine threonylcarbamoyltransferase Kae1/OSGEP GO:0000408|GO:0002949 Reactome: R-HSA-6782315 TON_1634 15a3d984c266e1c378746b6fdd5180e0 325 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 4 291 1.1E-101 T 23-10-2018 IPR017861 Kae1/TsaD family TON_1648 e3849122494899f175c777a034d7c935 250 Hamap MF_00722 Endonuclease NucS [nucS]. 28 241 38.619 T 23-10-2018 IPR002793 Endonuclease NucS GO:0004519 TON_1648 e3849122494899f175c777a034d7c935 250 Pfam PF01939 Endonuclease NucS 26 241 7.4E-89 T 23-10-2018 IPR002793 Endonuclease NucS GO:0004519 TON_1648 e3849122494899f175c777a034d7c935 250 Gene3D G3DSA:2.70.180.20 1 124 3.0E-42 T 23-10-2018 TON_1648 e3849122494899f175c777a034d7c935 250 Gene3D G3DSA:3.40.1350.10 125 236 7.4E-42 T 23-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 TON_1178 a7589195e5fd140b0b678eeb679ae1bf 576 Pfam PF00482 Type II secretion system (T2SS), protein F 338 462 2.1E-8 T 23-10-2018 IPR018076 Type II secretion system F domain TON_1178 a7589195e5fd140b0b678eeb679ae1bf 576 Pfam PF00482 Type II secretion system (T2SS), protein F 88 215 2.6E-8 T 23-10-2018 IPR018076 Type II secretion system F domain TON_0584 275f6a230a70541de4ee307bb96f4934 382 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 22 258 1.0E-80 T 23-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 TON_0584 275f6a230a70541de4ee307bb96f4934 382 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 282 376 1.4E-20 T 23-10-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II TON_0584 275f6a230a70541de4ee307bb96f4934 382 SUPERFAMILY SSF52922 274 379 3.4E-27 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TON_0584 275f6a230a70541de4ee307bb96f4934 382 Gene3D G3DSA:3.40.50.920 272 381 4.2E-26 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TON_0584 275f6a230a70541de4ee307bb96f4934 382 SUPERFAMILY SSF52518 12 265 1.03E-70 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold TON_0584 275f6a230a70541de4ee307bb96f4934 382 Gene3D G3DSA:3.40.50.970 1 199 3.4E-84 T 23-10-2018 TON_1221 d2bc67fc8638b5d3abc636778fe06a28 364 Pfam PF01170 Putative RNA methylase family UPF0020 173 319 2.8E-13 T 23-10-2018 IPR000241 Putative RNA methylase domain TON_1221 d2bc67fc8638b5d3abc636778fe06a28 364 Gene3D G3DSA:3.40.50.150 169 349 3.3E-27 T 23-10-2018 TON_1221 d2bc67fc8638b5d3abc636778fe06a28 364 SUPERFAMILY SSF53335 169 337 3.8E-21 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TON_1908 4eb1baf1d12645ede3ad97647ddb358f 426 SUPERFAMILY SSF54897 41 92 1.25E-7 T 23-10-2018 TON_1908 4eb1baf1d12645ede3ad97647ddb358f 426 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 139 150 - T 23-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site TON_1908 4eb1baf1d12645ede3ad97647ddb358f 426 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 181 191 - T 23-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site TON_1908 4eb1baf1d12645ede3ad97647ddb358f 426 Gene3D G3DSA:3.40.50.200 106 426 2.9E-110 T 23-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 TON_1908 4eb1baf1d12645ede3ad97647ddb358f 426 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 350 360 - T 23-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site TON_1908 4eb1baf1d12645ede3ad97647ddb358f 426 Gene3D G3DSA:3.30.70.80 31 95 1.1E-27 T 23-10-2018 IPR037045 Peptidase S8 propeptide/proteinase inhibitor I9 superfamily Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 TON_1908 4eb1baf1d12645ede3ad97647ddb358f 426 SUPERFAMILY SSF52743 110 424 4.58E-85 T 23-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 TON_1908 4eb1baf1d12645ede3ad97647ddb358f 426 PRINTS PR00723 Subtilisin serine protease family (S8) signature 349 365 4.2E-21 T 23-10-2018 IPR015500 Peptidase S8, subtilisin-related TON_1908 4eb1baf1d12645ede3ad97647ddb358f 426 PRINTS PR00723 Subtilisin serine protease family (S8) signature 134 153 4.2E-21 T 23-10-2018 IPR015500 Peptidase S8, subtilisin-related TON_1908 4eb1baf1d12645ede3ad97647ddb358f 426 PRINTS PR00723 Subtilisin serine protease family (S8) signature 177 190 4.2E-21 T 23-10-2018 IPR015500 Peptidase S8, subtilisin-related TON_1908 4eb1baf1d12645ede3ad97647ddb358f 426 Pfam PF00082 Subtilase family 138 413 8.4E-49 T 23-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 TON_1001 19224e3dda7bf4eb9539997b9a7d3204 472 Pfam PF13380 CoA binding domain 16 145 2.7E-25 T 23-10-2018 IPR003781 CoA-binding GO:0048037 TON_1001 19224e3dda7bf4eb9539997b9a7d3204 472 SUPERFAMILY SSF52210 143 304 2.09E-44 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TON_1001 19224e3dda7bf4eb9539997b9a7d3204 472 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 167 303 1.1E-56 T 23-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain TON_1001 19224e3dda7bf4eb9539997b9a7d3204 472 SMART SM00881 12 111 6.2E-37 T 23-10-2018 IPR003781 CoA-binding GO:0048037 TON_1001 19224e3dda7bf4eb9539997b9a7d3204 472 SUPERFAMILY SSF52210 311 468 1.96E-40 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TON_1001 19224e3dda7bf4eb9539997b9a7d3204 472 Gene3D G3DSA:3.40.50.261 308 470 2.2E-51 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TON_1001 19224e3dda7bf4eb9539997b9a7d3204 472 Gene3D G3DSA:3.40.50.720 9 140 2.2E-43 T 23-10-2018 TON_1001 19224e3dda7bf4eb9539997b9a7d3204 472 SUPERFAMILY SSF51735 10 141 1.15E-38 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TON_1001 19224e3dda7bf4eb9539997b9a7d3204 472 Gene3D G3DSA:3.40.50.261 142 306 1.7E-60 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TON_1206 683ac1a159cf9bb3f5c98d080234a93d 248 Gene3D G3DSA:1.25.10.10 1 247 1.1E-71 T 23-10-2018 IPR011989 Armadillo-like helical TON_1206 683ac1a159cf9bb3f5c98d080234a93d 248 SUPERFAMILY SSF48371 24 223 4.87E-21 T 23-10-2018 IPR016024 Armadillo-type fold TON_1589 ded1b2a035059a0e3d31a1d2af2b1b11 532 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 86 111 6.2E-10 T 23-10-2018 TON_1589 ded1b2a035059a0e3d31a1d2af2b1b11 532 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 114 134 6.2E-10 T 23-10-2018 TON_1589 ded1b2a035059a0e3d31a1d2af2b1b11 532 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 226 247 6.2E-10 T 23-10-2018 TON_1589 ded1b2a035059a0e3d31a1d2af2b1b11 532 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 76 124 6.3E-12 T 23-10-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_1589 ded1b2a035059a0e3d31a1d2af2b1b11 532 Pfam PF00361 Proton-conducting membrane transporter 138 451 2.6E-58 T 23-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_0668 8fb41748b01174d6241d6fd9b5ef0070 39 Pfam PF01544 CorA-like Mg2+ transporter protein 1 35 2.0E-8 T 23-10-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 TON_0668 8fb41748b01174d6241d6fd9b5ef0070 39 Gene3D G3DSA:1.20.58.340 1 39 4.1E-14 T 23-10-2018 TON_0668 8fb41748b01174d6241d6fd9b5ef0070 39 SUPERFAMILY SSF144083 1 37 2.22E-9 T 23-10-2018 TON_0172 36720857a10b36de497b63e9d284a6cf 773 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 149 692 1.9E-80 T 23-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit TON_0172 36720857a10b36de497b63e9d284a6cf 773 TIGRFAM TIGR02123 TRAP_fused: TRAP transporter, 4TM/12TM fusion protein 65 745 1.2E-164 T 23-10-2018 IPR011853 TRAP C4-dicarboxylate transport system permease, fused DctM-DctQ TON_1248 5e3ca2886ff8010ab49e034c34095a50 425 Pfam PF12804 MobA-like NTP transferase domain 6 113 5.0E-16 T 23-10-2018 IPR025877 MobA-like NTP transferase TON_1248 5e3ca2886ff8010ab49e034c34095a50 425 SUPERFAMILY SSF53448 5 220 3.55E-34 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TON_1248 5e3ca2886ff8010ab49e034c34095a50 425 Gene3D G3DSA:3.90.550.10 2 219 8.1E-57 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TON_1248 5e3ca2886ff8010ab49e034c34095a50 425 Pfam PF01066 CDP-alcohol phosphatidyltransferase 254 316 4.7E-11 T 23-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 TON_1248 5e3ca2886ff8010ab49e034c34095a50 425 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 294 316 - T 23-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 TON_1248 5e3ca2886ff8010ab49e034c34095a50 425 Gene3D G3DSA:1.20.120.1760 229 420 1.5E-55 T 23-10-2018 TON_0754 f52b8bda5d087168edba2ac64278eeaa 178 Gene3D G3DSA:3.40.50.300 60 159 1.4E-13 T 23-10-2018 TON_0754 f52b8bda5d087168edba2ac64278eeaa 178 Pfam PF01637 ATPase domain predominantly from Archaea 4 162 2.4E-20 T 23-10-2018 IPR011579 ATPase domain GO:0005524 TON_0754 f52b8bda5d087168edba2ac64278eeaa 178 SUPERFAMILY SSF52540 3 169 5.22E-23 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_1359 6fdfbd46fd1ac2aa6c06e8679873ae57 263 PIRSF PIRSF006601 17 263 1.1E-84 T 23-10-2018 IPR012096 ATPase, PP-loop, MJ1638-related TON_1359 6fdfbd46fd1ac2aa6c06e8679873ae57 263 Gene3D G3DSA:3.40.50.620 72 248 2.9E-12 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TON_1359 6fdfbd46fd1ac2aa6c06e8679873ae57 263 SUPERFAMILY SSF52402 67 207 3.26E-16 T 23-10-2018 TON_0877 e811b7d1f3c2d94f4f394b85b1f1717a 197 Gene3D G3DSA:1.20.1260.10 23 175 2.3E-31 T 23-10-2018 IPR012347 Ferritin-like TON_0877 e811b7d1f3c2d94f4f394b85b1f1717a 197 SUPERFAMILY SSF47240 27 177 2.66E-21 T 23-10-2018 IPR009078 Ferritin-like superfamily TON_0877 e811b7d1f3c2d94f4f394b85b1f1717a 197 Pfam PF02915 Rubrerythrin 30 170 2.9E-13 T 23-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 TON_0813 83aa6227c3cf045b45f9cffda58bd71c 290 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 8 271 7.8E-43 T 23-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD TON_0813 83aa6227c3cf045b45f9cffda58bd71c 290 TIGRFAM TIGR00374 TIGR00374: TIGR00374 family protein 19 143 1.3E-15 T 23-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD TON_0813 83aa6227c3cf045b45f9cffda58bd71c 290 TIGRFAM TIGR00374 TIGR00374: TIGR00374 family protein 172 278 7.8E-22 T 23-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD TON_0790 250338e4eea72f1ad6dc1c5245a20ae7 212 PIRSF PIRSF005785 1 212 6.6E-35 T 23-10-2018 IPR012091 Peptidase M54, archaemetzincin, archaeal/bacterial GO:0006508|GO:0008237|GO:0008270 TON_0790 250338e4eea72f1ad6dc1c5245a20ae7 212 SUPERFAMILY SSF55486 158 205 1.14E-9 T 23-10-2018 TON_0790 250338e4eea72f1ad6dc1c5245a20ae7 212 Pfam PF07998 Peptidase family M54 1 209 4.8E-46 T 23-10-2018 IPR012962 Peptidase M54, archaemetzincin GO:0008270 TON_0790 250338e4eea72f1ad6dc1c5245a20ae7 212 Gene3D G3DSA:3.40.390.10 68 209 1.3E-18 T 23-10-2018 IPR024079 Metallopeptidase, catalytic domain superfamily GO:0008237 TON_1607 172810687f15f1ce51257b66bf90cd89 94 SUPERFAMILY SSF111057 2 76 2.35E-24 T 23-10-2018 IPR036216 Hypothetical protein UCP004604 superfamily TON_1607 172810687f15f1ce51257b66bf90cd89 94 Pfam PF08967 Domain of unknown function (DUF1884) 1 78 1.4E-24 T 23-10-2018 IPR014418 Uncharacterised conserved protein UCP004604 TON_1607 172810687f15f1ce51257b66bf90cd89 94 ProDom PD029791 ORF 3'REGION GAP PF1875 PF0899 PH1831 B PHS036 4 76 7.0E-21 T 23-10-2018 IPR014418 Uncharacterised conserved protein UCP004604 TON_1607 172810687f15f1ce51257b66bf90cd89 94 PIRSF PIRSF004604 1 93 2.5E-31 T 23-10-2018 IPR014418 Uncharacterised conserved protein UCP004604 TON_1607 172810687f15f1ce51257b66bf90cd89 94 Gene3D G3DSA:3.30.2320.10 1 77 3.9E-22 T 23-10-2018 TON_0739 00e9a72ac582dd35c907f338c50132d7 263 Pfam PF13522 Glutamine amidotransferase domain 81 155 5.2E-8 T 23-10-2018 TON_0739 00e9a72ac582dd35c907f338c50132d7 263 SUPERFAMILY SSF56235 32 247 1.03E-15 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TON_0739 00e9a72ac582dd35c907f338c50132d7 263 Gene3D G3DSA:3.60.20.10 34 261 1.1E-16 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TON_0214 20f3009d7c2c1722764b6145a2f7a9af 502 Gene3D G3DSA:3.40.640.10 86 315 1.4E-60 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TON_0214 20f3009d7c2c1722764b6145a2f7a9af 502 Gene3D G3DSA:3.90.1150.10 340 475 1.4E-44 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TON_0214 20f3009d7c2c1722764b6145a2f7a9af 502 SUPERFAMILY SSF53383 12 488 1.73E-121 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TON_0214 20f3009d7c2c1722764b6145a2f7a9af 502 Hamap MF_00713 Probable glycine dehydrogenase (decarboxylating) subunit 2 [gcvPB]. 10 490 61.476 T 23-10-2018 IPR023012 Probable glycine dehydrogenase (decarboxylating) subunit 2 GO:0004375|GO:0019464 KEGG: 00260+1.4.4.2 TON_0214 20f3009d7c2c1722764b6145a2f7a9af 502 Pfam PF02347 Glycine cleavage system P-protein 34 309 2.6E-10 T 23-10-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 TON_1184 319ed153f774d5168c128ce26907a1cf 158 SUPERFAMILY SSF58100 41 140 2.2E-5 T 23-10-2018 TON_1184 319ed153f774d5168c128ce26907a1cf 158 Pfam PF05377 Flagella accessory protein C (FlaC) 49 102 4.4E-21 T 23-10-2018 IPR009205 Predicted archaeal flagellar protein C TON_1184 319ed153f774d5168c128ce26907a1cf 158 Gene3D G3DSA:1.20.5.340 26 142 2.0E-6 T 23-10-2018 TON_1184 319ed153f774d5168c128ce26907a1cf 158 PIRSF PIRSF018660 6 158 6.2E-19 T 23-10-2018 IPR009205 Predicted archaeal flagellar protein C TON_0357 dcdc13f2c05f52af157d64df76d49911 268 Gene3D G3DSA:3.60.15.10 1 268 3.5E-73 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TON_0357 dcdc13f2c05f52af157d64df76d49911 268 SUPERFAMILY SSF56281 7 268 2.49E-32 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TON_0357 dcdc13f2c05f52af157d64df76d49911 268 Pfam PF00753 Metallo-beta-lactamase superfamily 22 144 1.2E-16 T 23-10-2018 IPR001279 Metallo-beta-lactamase TON_0357 dcdc13f2c05f52af157d64df76d49911 268 SMART SM00849 21 239 7.9E-11 T 23-10-2018 IPR001279 Metallo-beta-lactamase TON_1893 c10140a42603cc2bd268c9496dd1ece4 307 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 5 307 9.7E-151 T 23-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 TON_1893 c10140a42603cc2bd268c9496dd1ece4 307 Gene3D G3DSA:3.40.50.620 2 189 3.3E-75 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TON_1893 c10140a42603cc2bd268c9496dd1ece4 307 Gene3D G3DSA:3.30.300.10 190 307 1.6E-52 T 23-10-2018 TON_1893 c10140a42603cc2bd268c9496dd1ece4 307 SUPERFAMILY SSF54810 189 307 6.02E-45 T 23-10-2018 TON_1893 c10140a42603cc2bd268c9496dd1ece4 307 SUPERFAMILY SSF52402 2 224 3.97E-53 T 23-10-2018 TON_1893 c10140a42603cc2bd268c9496dd1ece4 307 Pfam PF00958 GMP synthase C terminal domain 217 306 3.1E-34 T 23-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 TON_1893 c10140a42603cc2bd268c9496dd1ece4 307 Hamap MF_00345 GMP synthase [glutamine-hydrolyzing] subunit B [guaAB]. 1 307 45.733 T 23-10-2018 IPR026598 GMP synthase subunit B KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 TON_1893 c10140a42603cc2bd268c9496dd1ece4 307 Pfam PF02540 NAD synthase 11 83 2.3E-6 T 23-10-2018 IPR022310 NAD/GMP synthase TON_1893 c10140a42603cc2bd268c9496dd1ece4 307 Pfam PF02540 NAD synthase 157 186 7.3E-5 T 23-10-2018 IPR022310 NAD/GMP synthase TON_0581 dc8ad312a158bd7b6760b193fd6a2882 156 Pfam PF02643 Uncharacterized ACR, COG1430 14 114 8.6E-18 T 23-10-2018 IPR003795 Protein of unknown function DUF192 TON_0581 dc8ad312a158bd7b6760b193fd6a2882 156 Hamap MF_00263 UPF0127 protein . 2 116 29.176 T 23-10-2018 IPR022906 Uncharacterised protein family UPF0127 TON_0581 dc8ad312a158bd7b6760b193fd6a2882 156 Gene3D G3DSA:2.60.120.1140 1 124 2.5E-12 T 23-10-2018 IPR038695 Saro_0823-like superfamily TON_1108 b34ee47d9e180f1730e93b6798e3c7bb 91 SUPERFAMILY SSF54575 7 83 2.22E-23 T 23-10-2018 IPR023621 Ribosomal protein L31e domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_1108 b34ee47d9e180f1730e93b6798e3c7bb 91 Pfam PF01198 Ribosomal protein L31e 12 79 6.4E-11 T 23-10-2018 IPR000054 Ribosomal protein L31e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_1108 b34ee47d9e180f1730e93b6798e3c7bb 91 ProDom PD006030 RIBOSOMAL 60S L31 RIBONUCLEOPROTEIN L31E 50S L31 SUBUNIT STRAIN PHOSPHORYLATION 34 58 6.0E-5 T 23-10-2018 IPR000054 Ribosomal protein L31e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_1108 b34ee47d9e180f1730e93b6798e3c7bb 91 Gene3D G3DSA:3.10.440.10 3 91 1.1E-26 T 23-10-2018 IPR023621 Ribosomal protein L31e domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_1108 b34ee47d9e180f1730e93b6798e3c7bb 91 SMART SM01380 8 84 2.1E-22 T 23-10-2018 IPR000054 Ribosomal protein L31e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_1108 b34ee47d9e180f1730e93b6798e3c7bb 91 Hamap MF_00410 50S ribosomal protein L31e [rpl31e]. 4 90 23.099 T 23-10-2018 IPR000054 Ribosomal protein L31e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_1108 b34ee47d9e180f1730e93b6798e3c7bb 91 ProSitePatterns PS01144 Ribosomal protein L31e signature. 48 62 - T 23-10-2018 IPR020052 Ribosomal protein L31e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_1751 da21050f27dc63cd1114c4ed0d57d662 102 SUPERFAMILY SSF159468 3 100 4.19E-19 T 23-10-2018 IPR036906 ATPase, V1 complex, subunit F superfamily GO:0034220 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TON_1751 da21050f27dc63cd1114c4ed0d57d662 102 Pfam PF01990 ATP synthase (F/14-kDa) subunit 3 91 1.6E-17 T 23-10-2018 IPR008218 ATPase, V1 complex, subunit F GO:0034220 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TON_1751 da21050f27dc63cd1114c4ed0d57d662 102 Gene3D G3DSA:3.40.50.10580 1 102 2.2E-32 T 23-10-2018 IPR036906 ATPase, V1 complex, subunit F superfamily GO:0034220 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TON_1751 da21050f27dc63cd1114c4ed0d57d662 102 Hamap MF_00312 V-type ATP synthase subunit F [atpF]. 1 101 18.857 T 23-10-2018 IPR022944 ATPase, V1 complex, subunit F, bacterial/archaeal TON_0731 ae953789e14489da6ce39a2b238873fd 276 Pfam PF09968 Uncharacterized protein domain (DUF2202) 58 217 1.6E-66 T 23-10-2018 IPR019243 Domain of unknown function DUF2202 TON_0731 ae953789e14489da6ce39a2b238873fd 276 SUPERFAMILY SSF47240 58 198 1.08E-13 T 23-10-2018 IPR009078 Ferritin-like superfamily TON_0731 ae953789e14489da6ce39a2b238873fd 276 Gene3D G3DSA:1.20.1260.10 53 224 2.2E-70 T 23-10-2018 IPR012347 Ferritin-like TON_1633 582a7071429c49cb39409efbefec048c 263 Pfam PF05763 Protein of unknown function (DUF835) 133 249 1.3E-26 T 23-10-2018 IPR008553 Domain of unknown function DUF835 TON_1534 e0a18e505e1349c6883d062daa04f38c 183 Pfam PF04407 Protein of unknown function (DUF531) 1 169 9.3E-80 T 23-10-2018 IPR007501 Protein of unknown function DUF531 TON_1534 e0a18e505e1349c6883d062daa04f38c 183 PIRSF PIRSF006006 1 178 1.5E-86 T 23-10-2018 IPR007501 Protein of unknown function DUF531 TON_0482 678f51df13e12a6bf502e34f2ca64426 153 SMART SM00344 7 113 6.5E-43 T 23-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 TON_0482 678f51df13e12a6bf502e34f2ca64426 153 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 7 23 2.7E-13 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TON_0482 678f51df13e12a6bf502e34f2ca64426 153 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 23 34 2.7E-13 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TON_0482 678f51df13e12a6bf502e34f2ca64426 153 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 34 53 2.7E-13 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TON_0482 678f51df13e12a6bf502e34f2ca64426 153 Pfam PF01037 Lrp/AsnC ligand binding domain 73 142 2.1E-15 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain TON_0482 678f51df13e12a6bf502e34f2ca64426 153 Pfam PF13404 AsnC-type helix-turn-helix domain 7 47 2.3E-16 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TON_0482 678f51df13e12a6bf502e34f2ca64426 153 Gene3D G3DSA:3.30.70.920 59 148 9.0E-22 T 23-10-2018 TON_0482 678f51df13e12a6bf502e34f2ca64426 153 SUPERFAMILY SSF46785 7 75 4.55E-16 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TON_0482 678f51df13e12a6bf502e34f2ca64426 153 Gene3D G3DSA:1.10.10.10 4 58 6.9E-22 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TON_0482 678f51df13e12a6bf502e34f2ca64426 153 SUPERFAMILY SSF54909 67 144 1.34E-17 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel TON_0526 b273c74f991aaf805e6f58977cdd8c6e 123 Pfam PF14464 Prokaryotic homologs of the JAB domain 13 101 3.7E-10 T 23-10-2018 IPR028090 JAB domain, prokaryotic TON_0526 b273c74f991aaf805e6f58977cdd8c6e 123 Gene3D G3DSA:3.40.140.10 2 123 5.1E-27 T 23-10-2018 TON_0526 b273c74f991aaf805e6f58977cdd8c6e 123 SUPERFAMILY SSF102712 3 121 1.83E-27 T 23-10-2018 TON_0296 b9decd74674d500cc876974ccb8f5128 536 Pfam PF01497 Periplasmic binding protein 236 477 2.2E-35 T 23-10-2018 IPR002491 ABC transporter periplasmic binding domain TON_0296 b9decd74674d500cc876974ccb8f5128 536 Gene3D G3DSA:3.40.50.1980 204 532 3.7E-90 T 23-10-2018 TON_0296 b9decd74674d500cc876974ccb8f5128 536 SUPERFAMILY SSF53807 220 528 2.86E-70 T 23-10-2018 TON_0296 b9decd74674d500cc876974ccb8f5128 536 SUPERFAMILY SSF56524 57 200 1.44E-12 T 23-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 TON_0848 bf7abda5cfc0b3bec3daa469b9c9f540 191 Pfam PF03358 NADPH-dependent FMN reductase 1 135 6.0E-28 T 23-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 TON_0848 bf7abda5cfc0b3bec3daa469b9c9f540 191 Gene3D G3DSA:3.40.50.360 1 190 4.1E-37 T 23-10-2018 IPR029039 Flavoprotein-like superfamily TON_0848 bf7abda5cfc0b3bec3daa469b9c9f540 191 SUPERFAMILY SSF52218 1 168 6.09E-33 T 23-10-2018 IPR029039 Flavoprotein-like superfamily TON_1603 8f1540a8428609520fd9d47a9fdf6841 330 SUPERFAMILY SSF51905 17 320 4.3E-62 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TON_1603 8f1540a8428609520fd9d47a9fdf6841 330 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 19 310 2.6E-61 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TON_1603 8f1540a8428609520fd9d47a9fdf6841 330 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 124 142 1.5E-40 T 23-10-2018 TON_1603 8f1540a8428609520fd9d47a9fdf6841 330 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 275 297 1.5E-40 T 23-10-2018 TON_1603 8f1540a8428609520fd9d47a9fdf6841 330 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 249 265 1.5E-40 T 23-10-2018 TON_1603 8f1540a8428609520fd9d47a9fdf6841 330 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 20 39 1.5E-40 T 23-10-2018 TON_1603 8f1540a8428609520fd9d47a9fdf6841 330 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 166 184 1.5E-40 T 23-10-2018 TON_1603 8f1540a8428609520fd9d47a9fdf6841 330 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 18 321 4.4E-123 T 23-10-2018 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00450+1.8.1.9 TON_1603 8f1540a8428609520fd9d47a9fdf6841 330 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 154 174 - T 23-10-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 TON_1603 8f1540a8428609520fd9d47a9fdf6841 330 Gene3D G3DSA:3.50.50.60 136 257 1.3E-116 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TON_1603 8f1540a8428609520fd9d47a9fdf6841 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 19 41 1.1E-66 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TON_1603 8f1540a8428609520fd9d47a9fdf6841 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 285 303 1.1E-66 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TON_1603 8f1540a8428609520fd9d47a9fdf6841 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 72 82 1.1E-66 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TON_1603 8f1540a8428609520fd9d47a9fdf6841 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 125 133 1.1E-66 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TON_1603 8f1540a8428609520fd9d47a9fdf6841 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 213 229 1.1E-66 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TON_1603 8f1540a8428609520fd9d47a9fdf6841 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 51 66 1.1E-66 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TON_1603 8f1540a8428609520fd9d47a9fdf6841 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 147 159 1.1E-66 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TON_1603 8f1540a8428609520fd9d47a9fdf6841 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 162 186 1.1E-66 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TON_1603 8f1540a8428609520fd9d47a9fdf6841 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 251 272 1.1E-66 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TON_1603 8f1540a8428609520fd9d47a9fdf6841 330 Gene3D G3DSA:3.50.50.60 18 315 1.3E-116 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TON_0980 ec4d04aec2721b7b2fa4e44329f25572 153 Gene3D G3DSA:1.10.10.10 1 55 3.6E-19 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TON_0980 ec4d04aec2721b7b2fa4e44329f25572 153 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 4 20 5.3E-14 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TON_0980 ec4d04aec2721b7b2fa4e44329f25572 153 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 31 50 5.3E-14 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TON_0980 ec4d04aec2721b7b2fa4e44329f25572 153 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 20 31 5.3E-14 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TON_0980 ec4d04aec2721b7b2fa4e44329f25572 153 SUPERFAMILY SSF46785 4 62 2.81E-15 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TON_0980 ec4d04aec2721b7b2fa4e44329f25572 153 Pfam PF13412 Winged helix-turn-helix DNA-binding 5 51 8.1E-14 T 23-10-2018 TON_0980 ec4d04aec2721b7b2fa4e44329f25572 153 Gene3D G3DSA:3.30.70.920 56 148 2.8E-9 T 23-10-2018 TON_0980 ec4d04aec2721b7b2fa4e44329f25572 153 SUPERFAMILY SSF54909 68 147 6.03E-5 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel TON_0980 ec4d04aec2721b7b2fa4e44329f25572 153 SMART SM00344 4 112 6.2E-33 T 23-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 TON_0849 6c4f961435941677722502a5e98dee1f 371 SUPERFAMILY SSF101960 10 352 2.62E-40 T 23-10-2018 IPR037284 SUF system FeS cluster assembly, SufBD superfamily TON_0849 6c4f961435941677722502a5e98dee1f 371 Pfam PF01458 Uncharacterized protein family (UPF0051) 130 343 4.2E-30 T 23-10-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 TON_0639 a0b3a404e0b8604fda8c9648331d2989 334 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 139 146 - T 23-10-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 TON_0639 a0b3a404e0b8604fda8c9648331d2989 334 TIGRFAM TIGR01546 GAPDH-II_archae: glyceraldehyde-3-phosphate dehydrogenase, type II 5 333 7.5E-183 T 23-10-2018 IPR006436 Glyceraldehyde-3-phosphate dehydrogenase, type II GO:0005737|GO:0006096|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.59|KEGG: 00710+1.2.1.59 TON_0639 a0b3a404e0b8604fda8c9648331d2989 334 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 147 296 1.2E-29 T 23-10-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 TON_0639 a0b3a404e0b8604fda8c9648331d2989 334 SMART SM00846 3 141 1.7E-20 T 23-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 TON_0639 a0b3a404e0b8604fda8c9648331d2989 334 SUPERFAMILY SSF51735 3 158 5.92E-47 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TON_0639 a0b3a404e0b8604fda8c9648331d2989 334 PIRSF PIRSF000149 1 318 6.4E-86 T 23-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 TON_0639 a0b3a404e0b8604fda8c9648331d2989 334 Gene3D G3DSA:3.40.50.720 3 331 3.5E-147 T 23-10-2018 TON_0639 a0b3a404e0b8604fda8c9648331d2989 334 Gene3D G3DSA:3.30.360.10 140 301 3.5E-147 T 23-10-2018 TON_0639 a0b3a404e0b8604fda8c9648331d2989 334 SUPERFAMILY SSF55347 140 301 2.24E-51 T 23-10-2018 TON_0639 a0b3a404e0b8604fda8c9648331d2989 334 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 3 108 2.2E-13 T 23-10-2018 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 TON_0639 a0b3a404e0b8604fda8c9648331d2989 334 Hamap MF_00559 Glyceraldehyde-3-phosphate dehydrogenase [gap]. 1 334 189.376 T 23-10-2018 IPR006436 Glyceraldehyde-3-phosphate dehydrogenase, type II GO:0005737|GO:0006096|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.59|KEGG: 00710+1.2.1.59 TON_0406 2675f9c028db1b3dbb0eec76e8531598 116 SUPERFAMILY SSF50104 24 114 2.8E-31 T 23-10-2018 IPR008991 Translation protein SH3-like domain superfamily TON_0406 2675f9c028db1b3dbb0eec76e8531598 116 ProSitePatterns PS01171 Ribosomal protein L21e signature. 56 81 - T 23-10-2018 IPR018259 Ribosomal protein L21e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0406 2675f9c028db1b3dbb0eec76e8531598 116 Pfam PF01157 Ribosomal protein L21e 24 113 4.5E-32 T 23-10-2018 IPR001147 Ribosomal protein L21e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0406 2675f9c028db1b3dbb0eec76e8531598 116 Gene3D G3DSA:2.30.30.70 20 115 1.6E-36 T 23-10-2018 IPR036948 Ribosomal protein L21 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0406 2675f9c028db1b3dbb0eec76e8531598 116 Hamap MF_00369 50S ribosomal protein L21e [rpl21e]. 21 115 30.012 T 23-10-2018 IPR022856 Ribosomal protein L21e, archaeal TON_1513 570f35909563febd2fbe59c979c68884 185 SUPERFAMILY SSF53271 3 162 3.63E-46 T 23-10-2018 IPR029057 Phosphoribosyltransferase-like TON_1513 570f35909563febd2fbe59c979c68884 185 Pfam PF00156 Phosphoribosyl transferase domain 37 162 1.2E-22 T 23-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 TON_1513 570f35909563febd2fbe59c979c68884 185 TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase 12 171 4.3E-51 T 23-10-2018 IPR004467 Orotate phosphoribosyl transferase domain GO:0004588 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TON_1513 570f35909563febd2fbe59c979c68884 185 Gene3D G3DSA:3.40.50.2020 1 176 4.2E-59 T 23-10-2018 TON_1513 570f35909563febd2fbe59c979c68884 185 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 185 27.193 T 23-10-2018 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TON_0372 78536598e591aa351e14dee858c37213 174 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 89 121 5.0E-8 T 23-10-2018 IPR001451 Hexapeptide repeat TON_0372 78536598e591aa351e14dee858c37213 174 SUPERFAMILY SSF51161 3 168 7.9E-52 T 23-10-2018 IPR011004 Trimeric LpxA-like superfamily TON_0372 78536598e591aa351e14dee858c37213 174 Gene3D G3DSA:2.160.10.10 1 172 2.7E-65 T 23-10-2018 TON_1920 2b90c5c355fb318a3d0626cbb6a6c36e 113 SUPERFAMILY SSF46785 3 105 1.21E-16 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TON_1920 2b90c5c355fb318a3d0626cbb6a6c36e 113 Gene3D G3DSA:1.10.10.10 1 109 2.0E-36 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TON_1920 2b90c5c355fb318a3d0626cbb6a6c36e 113 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 12 83 4.4E-10 T 23-10-2018 IPR002831 Transcription regulator TrmB, N-terminal TON_1279 53948db1d450fbe2f753147ecd5fe225 412 PRINTS PR01035 Tetracycline resistance protein signature 305 329 2.0E-6 T 23-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 TON_1279 53948db1d450fbe2f753147ecd5fe225 412 PRINTS PR01035 Tetracycline resistance protein signature 363 385 2.0E-6 T 23-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 TON_1279 53948db1d450fbe2f753147ecd5fe225 412 PRINTS PR01035 Tetracycline resistance protein signature 274 293 2.0E-6 T 23-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 TON_1279 53948db1d450fbe2f753147ecd5fe225 412 Pfam PF07690 Major Facilitator Superfamily 33 271 1.9E-29 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TON_1279 53948db1d450fbe2f753147ecd5fe225 412 Pfam PF07690 Major Facilitator Superfamily 274 408 1.3E-21 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TON_1279 53948db1d450fbe2f753147ecd5fe225 412 Gene3D G3DSA:1.20.1250.20 243 412 5.2E-28 T 23-10-2018 TON_1279 53948db1d450fbe2f753147ecd5fe225 412 Gene3D G3DSA:1.20.1250.20 21 242 8.8E-35 T 23-10-2018 TON_1279 53948db1d450fbe2f753147ecd5fe225 412 SUPERFAMILY SSF103473 25 410 7.32E-59 T 23-10-2018 IPR036259 MFS transporter superfamily TON_0447 5463c68c430f7fb7e5b6aaec012fc625 372 Gene3D G3DSA:1.25.40.10 2 349 6.8E-64 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TON_0447 5463c68c430f7fb7e5b6aaec012fc625 372 Pfam PF13424 Tetratricopeptide repeat 63 135 6.9E-8 T 23-10-2018 TON_0447 5463c68c430f7fb7e5b6aaec012fc625 372 SUPERFAMILY SSF48452 62 340 1.7E-11 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TON_0447 5463c68c430f7fb7e5b6aaec012fc625 372 SMART SM00028 64 97 0.0071 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TON_0447 5463c68c430f7fb7e5b6aaec012fc625 372 SMART SM00028 104 137 35.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TON_0382 4772a4b578a4e9dd43f9788fad84a636 268 Pfam PF01261 Xylose isomerase-like TIM barrel 30 228 1.6E-16 T 23-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain TON_0382 4772a4b578a4e9dd43f9788fad84a636 268 SUPERFAMILY SSF51658 1 238 1.7E-27 T 23-10-2018 IPR036237 Xylose isomerase-like superfamily TON_0382 4772a4b578a4e9dd43f9788fad84a636 268 Gene3D G3DSA:3.20.20.150 1 255 5.8E-27 T 23-10-2018 TON_1794 7148acf33f8817a298294071ba183f16 299 SUPERFAMILY SSF160964 7 43 8.76E-8 T 23-10-2018 TON_1794 7148acf33f8817a298294071ba183f16 299 SUPERFAMILY SSF161098 58 284 6.02E-49 T 23-10-2018 IPR035906 MetI-like superfamily TON_1794 7148acf33f8817a298294071ba183f16 299 Gene3D G3DSA:1.10.3720.10 54 296 1.8E-57 T 23-10-2018 IPR035906 MetI-like superfamily TON_1794 7148acf33f8817a298294071ba183f16 299 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 90 284 1.6E-15 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TON_1278 7e676b97f60b8dc25eaeceb04f1868d0 180 Hamap MF_00299 Probable RNA 2'-phosphotransferase [kptA]. 4 176 33.875 T 23-10-2018 IPR022928 RNA 2'-phosphotransferase KptA, putative GO:0016773 TON_1278 7e676b97f60b8dc25eaeceb04f1868d0 180 Pfam PF01885 RNA 2'-phosphotransferase, Tpt1 / KptA family 6 167 3.5E-33 T 23-10-2018 IPR002745 Phosphotransferase KptA/Tpt1 GO:0006388|GO:0016772 TON_1278 7e676b97f60b8dc25eaeceb04f1868d0 180 Gene3D G3DSA:3.20.170.30 95 180 1.3E-31 T 23-10-2018 TON_1278 7e676b97f60b8dc25eaeceb04f1868d0 180 Gene3D G3DSA:1.10.10.970 4 75 4.4E-22 T 23-10-2018 TON_1278 7e676b97f60b8dc25eaeceb04f1868d0 180 SUPERFAMILY SSF56399 7 178 2.88E-57 T 23-10-2018 TON_1319 bbe766fbe291448c849aac335641cf29 238 SUPERFAMILY SSF102215 1 235 1.83E-60 T 23-10-2018 IPR024087 Creatininase-like superfamily KEGG: 00740+3.5.1.102|MetaCyc: PWY-6167 TON_1319 bbe766fbe291448c849aac335641cf29 238 Gene3D G3DSA:3.40.50.10310 1 235 1.4E-65 T 23-10-2018 IPR024087 Creatininase-like superfamily KEGG: 00740+3.5.1.102|MetaCyc: PWY-6167 TON_1319 bbe766fbe291448c849aac335641cf29 238 Pfam PF02633 Creatinine amidohydrolase 4 233 6.5E-62 T 23-10-2018 IPR003785 Creatininase/formamide hydrolase KEGG: 00740+3.5.1.102|MetaCyc: PWY-6167 TON_1787 336b9a33d3fdc1348bdffc6b4adcf3c2 625 Pfam PF03169 OPT oligopeptide transporter protein 15 590 3.5E-101 T 23-10-2018 IPR004813 Oligopeptide transporter, OPT superfamily GO:0055085 TON_1787 336b9a33d3fdc1348bdffc6b4adcf3c2 625 TIGRFAM TIGR00733 TIGR00733: oligopeptide transporter, OPT family 15 592 4.5E-255 T 23-10-2018 IPR004814 Oligopeptide transporter OPT TON_1787 336b9a33d3fdc1348bdffc6b4adcf3c2 625 TIGRFAM TIGR00728 OPT_sfam: oligopeptide transporter, OPT superfamily 10 593 3.9E-122 T 23-10-2018 IPR004813 Oligopeptide transporter, OPT superfamily GO:0055085 TON_1565 bd623cfa97c7c6ce4c37627a20bd9174 480 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 241 267 2.1E-28 T 23-10-2018 TON_1565 bd623cfa97c7c6ce4c37627a20bd9174 480 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 76 101 2.1E-28 T 23-10-2018 TON_1565 bd623cfa97c7c6ce4c37627a20bd9174 480 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 111 131 2.1E-28 T 23-10-2018 TON_1565 bd623cfa97c7c6ce4c37627a20bd9174 480 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 157 178 2.1E-28 T 23-10-2018 TON_1565 bd623cfa97c7c6ce4c37627a20bd9174 480 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 310 322 2.1E-28 T 23-10-2018 TON_1565 bd623cfa97c7c6ce4c37627a20bd9174 480 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 219 240 2.1E-28 T 23-10-2018 TON_1565 bd623cfa97c7c6ce4c37627a20bd9174 480 Pfam PF00361 Proton-conducting membrane transporter 134 418 1.6E-47 T 23-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_1565 bd623cfa97c7c6ce4c37627a20bd9174 480 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 71 121 1.7E-6 T 23-10-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_0298 8265cf32a275b608a3285dd76659f4cd 259 SUPERFAMILY SSF52540 1 227 1.55E-61 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_0298 8265cf32a275b608a3285dd76659f4cd 259 Gene3D G3DSA:3.40.50.300 1 248 6.2E-67 T 23-10-2018 TON_0298 8265cf32a275b608a3285dd76659f4cd 259 Pfam PF00005 ABC transporter 17 165 3.6E-29 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TON_0298 8265cf32a275b608a3285dd76659f4cd 259 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TON_0298 8265cf32a275b608a3285dd76659f4cd 259 SMART SM00382 25 214 6.2E-14 T 23-10-2018 IPR003593 AAA+ ATPase domain TON_0368 1955b607b8fe308cc02fb085d4cc677a 129 Pfam PF01934 Protein of unknown function DUF86 8 123 5.8E-12 T 23-10-2018 IPR008201 Protein of unknown function DUF86 TON_0368 1955b607b8fe308cc02fb085d4cc677a 129 Gene3D G3DSA:1.20.120.580 1 127 1.6E-6 T 23-10-2018 IPR037038 Bsu32300-like superfamily TON_0368 1955b607b8fe308cc02fb085d4cc677a 129 SUPERFAMILY SSF81593 26 125 9.42E-5 T 23-10-2018 TON_1362 196d83e3f2141346c307aba4f91bd720 390 SUPERFAMILY SSF54675 2 115 1.44E-33 T 23-10-2018 TON_1362 196d83e3f2141346c307aba4f91bd720 390 PIRSF PIRSF000484 69 386 1.0E-49 T 23-10-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 TON_1362 196d83e3f2141346c307aba4f91bd720 390 PIRSF PIRSF000484 7 72 0.73 T 23-10-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 TON_1362 196d83e3f2141346c307aba4f91bd720 390 SUPERFAMILY SSF51690 112 386 9.03E-78 T 23-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 TON_1362 196d83e3f2141346c307aba4f91bd720 390 Gene3D G3DSA:3.20.140.10 318 387 2.5E-6 T 23-10-2018 TON_1362 196d83e3f2141346c307aba4f91bd720 390 Gene3D G3DSA:3.90.1170.20 1 106 1.9E-46 T 23-10-2018 IPR037128 Quinolinate phosphoribosyl transferase, N-terminal domain superfamily GO:0016763 Reactome: R-HSA-196807 TON_1362 196d83e3f2141346c307aba4f91bd720 390 Gene3D G3DSA:3.20.20.70 107 297 7.0E-65 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TON_1362 196d83e3f2141346c307aba4f91bd720 390 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 52 113 3.9E-6 T 23-10-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 TON_1362 196d83e3f2141346c307aba4f91bd720 390 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 115 303 6.5E-27 T 23-10-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 Reactome: R-HSA-196807 TON_0590 2c2239bd285a4560b916437c89c3104c 260 SUPERFAMILY SSF64167 3 256 3.01E-70 T 23-10-2018 TON_0590 2c2239bd285a4560b916437c89c3104c 260 TIGRFAM TIGR00087 surE: 5'/3'-nucleotidase SurE 3 244 7.9E-69 T 23-10-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 TON_0590 2c2239bd285a4560b916437c89c3104c 260 Hamap MF_00060 5'/3'-nucleotidase SurE [surE]. 2 260 32.708 T 23-10-2018 IPR030048 Survival protein SurE GO:0008252 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 TON_0590 2c2239bd285a4560b916437c89c3104c 260 Gene3D G3DSA:3.40.1210.10 3 258 5.2E-82 T 23-10-2018 IPR036523 SurE-like phosphatase/nucleotidase superfamily GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 TON_0590 2c2239bd285a4560b916437c89c3104c 260 Pfam PF01975 Survival protein SurE 4 194 3.2E-54 T 23-10-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 TON_0670 f6b92c5a436fad25adbabcbf16d41f4a 114 SUPERFAMILY SSF51182 11 101 2.42E-24 T 23-10-2018 IPR011051 RmlC-like cupin domain superfamily TON_0670 f6b92c5a436fad25adbabcbf16d41f4a 114 Pfam PF07883 Cupin domain 32 100 5.0E-19 T 23-10-2018 IPR013096 Cupin 2, conserved barrel TON_0670 f6b92c5a436fad25adbabcbf16d41f4a 114 Gene3D G3DSA:2.60.120.10 12 105 3.0E-22 T 23-10-2018 IPR014710 RmlC-like jelly roll fold TON_1889 7975a615e5d4c48a307a556fc8dd9397 277 Gene3D G3DSA:3.90.1170.20 10 271 2.1E-90 T 23-10-2018 IPR037128 Quinolinate phosphoribosyl transferase, N-terminal domain superfamily GO:0016763 Reactome: R-HSA-196807 TON_1889 7975a615e5d4c48a307a556fc8dd9397 277 Gene3D G3DSA:3.20.20.70 120 263 2.1E-90 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TON_1889 7975a615e5d4c48a307a556fc8dd9397 277 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 16 102 2.6E-31 T 23-10-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 TON_1889 7975a615e5d4c48a307a556fc8dd9397 277 SUPERFAMILY SSF54675 5 103 2.05E-30 T 23-10-2018 TON_1889 7975a615e5d4c48a307a556fc8dd9397 277 SUPERFAMILY SSF51690 104 273 1.02E-47 T 23-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 TON_1889 7975a615e5d4c48a307a556fc8dd9397 277 TIGRFAM TIGR00078 nadC: nicotinate-nucleotide diphosphorylase (carboxylating) 8 273 5.0E-97 T 23-10-2018 IPR004393 Nicotinate-nucleotide pyrophosphorylase GO:0004514|GO:0019363 KEGG: 00760+2.4.2.19|MetaCyc: PWY-5316|MetaCyc: PWY-5653|MetaCyc: PWY-7342|Reactome: R-HSA-196807 TON_1889 7975a615e5d4c48a307a556fc8dd9397 277 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 104 272 7.9E-51 T 23-10-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 Reactome: R-HSA-196807 TON_1889 7975a615e5d4c48a307a556fc8dd9397 277 PIRSF PIRSF006250 2 276 1.6E-91 T 23-10-2018 IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD Reactome: R-HSA-196807 TON_0424 6484b4bec4b3a2933799bcd87a01a41d 446 Pfam PF00999 Sodium/hydrogen exchanger family 20 423 1.7E-54 T 23-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 TON_0424 6484b4bec4b3a2933799bcd87a01a41d 446 Gene3D G3DSA:1.20.1530.20 12 435 2.3E-22 T 23-10-2018 IPR038770 Sodium/solute symporter superfamily TON_1591 b71482afadc4a6ed92dd0054d69a9178 175 Gene3D G3DSA:3.40.50.12280 7 172 3.5E-52 T 23-10-2018 TON_1591 b71482afadc4a6ed92dd0054d69a9178 175 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 47 156 4.7E-27 T 23-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_1591 b71482afadc4a6ed92dd0054d69a9178 175 SUPERFAMILY SSF56770 34 164 7.33E-53 T 23-10-2018 TON_1240 0532306f7df235f88d148275f23946b3 169 SUPERFAMILY SSF55811 37 167 2.03E-32 T 23-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 TON_1240 0532306f7df235f88d148275f23946b3 169 ProSitePatterns PS00893 Nudix box signature. 75 96 - T 23-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 TON_1240 0532306f7df235f88d148275f23946b3 169 Gene3D G3DSA:3.90.79.10 41 168 2.8E-42 T 23-10-2018 TON_1240 0532306f7df235f88d148275f23946b3 169 Pfam PF00293 NUDIX domain 47 164 4.6E-22 T 23-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 TON_1240 0532306f7df235f88d148275f23946b3 169 PRINTS PR00502 NUDIX hydrolase family signature 84 99 5.2E-7 T 23-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 TON_1240 0532306f7df235f88d148275f23946b3 169 PRINTS PR00502 NUDIX hydrolase family signature 70 84 5.2E-7 T 23-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 TON_0609 c710b9ba98319671597417cbacd68fd3 185 SUPERFAMILY SSF63380 2 81 3.66E-15 T 23-10-2018 IPR017938 Riboflavin synthase-like beta-barrel TON_0609 c710b9ba98319671597417cbacd68fd3 185 Gene3D G3DSA:2.40.30.20 90 185 1.0E-29 T 23-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TON_0609 c710b9ba98319671597417cbacd68fd3 185 Pfam PF00677 Lumazine binding domain 88 171 2.0E-22 T 23-10-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TON_0609 c710b9ba98319671597417cbacd68fd3 185 Pfam PF00677 Lumazine binding domain 4 75 1.0E-11 T 23-10-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TON_0609 c710b9ba98319671597417cbacd68fd3 185 TIGRFAM TIGR00187 ribE: riboflavin synthase, alpha subunit 2 180 4.9E-49 T 23-10-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TON_0609 c710b9ba98319671597417cbacd68fd3 185 Gene3D G3DSA:2.40.30.20 1 77 2.9E-15 T 23-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TON_0609 c710b9ba98319671597417cbacd68fd3 185 PIRSF PIRSF000498 1 185 1.0E-55 T 23-10-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TON_0609 c710b9ba98319671597417cbacd68fd3 185 SUPERFAMILY SSF63380 81 181 2.98E-29 T 23-10-2018 IPR017938 Riboflavin synthase-like beta-barrel TON_1299 0ad53d8d63c185f0731f8d1d34cc86c9 420 Gene3D G3DSA:1.10.246.90 244 368 2.6E-52 T 23-10-2018 TON_1299 0ad53d8d63c185f0731f8d1d34cc86c9 420 Gene3D G3DSA:1.10.287.660 131 243 2.2E-39 T 23-10-2018 IPR029012 Helix hairpin bin domain superfamily TON_1299 0ad53d8d63c185f0731f8d1d34cc86c9 420 Pfam PF01798 snoRNA binding domain, fibrillarin 138 363 1.4E-73 T 23-10-2018 IPR002687 Nop domain TON_1299 0ad53d8d63c185f0731f8d1d34cc86c9 420 SUPERFAMILY SSF89124 126 366 1.14E-81 T 23-10-2018 IPR036070 Nop domain superfamily TON_1299 0ad53d8d63c185f0731f8d1d34cc86c9 420 SMART SM00931 130 182 4.0E-28 T 23-10-2018 IPR012976 NOSIC TON_1299 0ad53d8d63c185f0731f8d1d34cc86c9 420 Gene3D G3DSA:3.30.420.220 1 125 2.9E-47 T 23-10-2018 TON_1299 0ad53d8d63c185f0731f8d1d34cc86c9 420 Gene3D G3DSA:1.10.150.460 161 212 2.2E-39 T 23-10-2018 TON_0414 804fc2599f79a9f8a5a2ab34f4068f77 274 ProDom PD039347 PF1398 MJ0538 PH1392 4 253 4.0E-68 T 23-10-2018 IPR020292 Uncharacterised protein family MJ0538 TON_0542 3183d2abca73ef2ffd7ed45e28b78d1a 352 SUPERFAMILY SSF51971 17 285 9.06E-55 T 23-10-2018 TON_0542 3183d2abca73ef2ffd7ed45e28b78d1a 352 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 19 338 4.0E-37 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TON_0542 3183d2abca73ef2ffd7ed45e28b78d1a 352 Gene3D G3DSA:3.50.50.60 22 344 1.6E-53 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TON_0542 3183d2abca73ef2ffd7ed45e28b78d1a 352 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 20 42 3.9E-13 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TON_0542 3183d2abca73ef2ffd7ed45e28b78d1a 352 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 170 194 3.9E-13 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TON_0542 3183d2abca73ef2ffd7ed45e28b78d1a 352 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 313 331 3.9E-13 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TON_0542 3183d2abca73ef2ffd7ed45e28b78d1a 352 Gene3D G3DSA:3.50.50.60 132 284 1.6E-53 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TON_0542 3183d2abca73ef2ffd7ed45e28b78d1a 352 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 303 325 1.2E-21 T 23-10-2018 TON_0542 3183d2abca73ef2ffd7ed45e28b78d1a 352 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 276 292 1.2E-21 T 23-10-2018 TON_0542 3183d2abca73ef2ffd7ed45e28b78d1a 352 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 119 137 1.2E-21 T 23-10-2018 TON_0542 3183d2abca73ef2ffd7ed45e28b78d1a 352 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 174 192 1.2E-21 T 23-10-2018 TON_0542 3183d2abca73ef2ffd7ed45e28b78d1a 352 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 21 40 1.2E-21 T 23-10-2018 TON_1778 684b2a6509df95606df980ab2ab52161 401 Pfam PF04104 Eukaryotic and archaeal DNA primase, large subunit 144 369 2.8E-30 T 23-10-2018 IPR007238 DNA primase large subunit, eukaryotic/archaeal GO:0003896|GO:0006269 Reactome: R-HSA-113501|Reactome: R-HSA-174411|Reactome: R-HSA-174430|Reactome: R-HSA-68952|Reactome: R-HSA-68962|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183 TON_1778 684b2a6509df95606df980ab2ab52161 401 Gene3D G3DSA:1.20.930.50 8 224 1.7E-46 T 23-10-2018 TON_1778 684b2a6509df95606df980ab2ab52161 401 Hamap MF_00701 DNA primase large subunit PriL [priL]. 1 389 28.87 T 23-10-2018 IPR023642 DNA primase large subunit PriL GO:0003896 TON_1778 684b2a6509df95606df980ab2ab52161 401 SUPERFAMILY SSF140914 2 249 1.44E-22 T 23-10-2018 TON_1778 684b2a6509df95606df980ab2ab52161 401 Gene3D G3DSA:2.20.20.80 109 171 1.7E-46 T 23-10-2018 TON_0586 93f2ad04d6bc6afae20d79fa8086b7f1 284 Gene3D G3DSA:3.40.50.970 69 251 4.1E-33 T 23-10-2018 TON_0586 93f2ad04d6bc6afae20d79fa8086b7f1 284 SUPERFAMILY SSF52518 19 274 9.03E-75 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold TON_0586 93f2ad04d6bc6afae20d79fa8086b7f1 284 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 57 205 1.1E-39 T 23-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 TON_0944 72b9b21b4b2263cd6d28f3bac425d4cb 248 Pfam PF01904 Protein of unknown function DUF72 26 246 1.2E-38 T 23-10-2018 IPR002763 Protein of unknown function DUF72 TON_0944 72b9b21b4b2263cd6d28f3bac425d4cb 248 SUPERFAMILY SSF117396 12 248 4.71E-50 T 23-10-2018 IPR036520 UPF0759 superfamily TON_0944 72b9b21b4b2263cd6d28f3bac425d4cb 248 Gene3D G3DSA:3.20.20.410 7 248 2.2E-44 T 23-10-2018 IPR036520 UPF0759 superfamily TON_1662 73ab1bcd3395064dd03119ecd859f4a5 101 ProDom PD012512 ARCHAEA PH1931 STS176 TA1183 MJ0319 PRECURSOR TVG0378908 UNCHARACTERIZED DUF211 AF1549 12 95 6.0E-39 T 23-10-2018 IPR003831 Protein of unknown function DUF211 TON_1662 73ab1bcd3395064dd03119ecd859f4a5 101 Gene3D G3DSA:3.30.70.1340 1 86 2.0E-34 T 23-10-2018 IPR023129 MTH889-like domain superfamily TON_1662 73ab1bcd3395064dd03119ecd859f4a5 101 Pfam PF02680 Uncharacterized ArCR, COG1888 5 90 2.0E-37 T 23-10-2018 IPR003831 Protein of unknown function DUF211 TON_1662 73ab1bcd3395064dd03119ecd859f4a5 101 SUPERFAMILY SSF160363 4 93 2.49E-34 T 23-10-2018 IPR023129 MTH889-like domain superfamily TON_0367 8e9d891a7e5664d7f829050237da1cf2 184 PIRSF PIRSF005785 1 184 6.3E-59 T 23-10-2018 IPR012091 Peptidase M54, archaemetzincin, archaeal/bacterial GO:0006508|GO:0008237|GO:0008270 TON_0367 8e9d891a7e5664d7f829050237da1cf2 184 SUPERFAMILY SSF55486 56 174 7.59E-16 T 23-10-2018 TON_0367 8e9d891a7e5664d7f829050237da1cf2 184 Pfam PF07998 Peptidase family M54 46 178 2.4E-30 T 23-10-2018 IPR012962 Peptidase M54, archaemetzincin GO:0008270 TON_0367 8e9d891a7e5664d7f829050237da1cf2 184 Hamap MF_01842 Archaemetzincin [amzA]. 1 177 34.178 T 23-10-2018 IPR012091 Peptidase M54, archaemetzincin, archaeal/bacterial GO:0006508|GO:0008237|GO:0008270 TON_0367 8e9d891a7e5664d7f829050237da1cf2 184 Gene3D G3DSA:3.40.390.10 7 183 2.1E-48 T 23-10-2018 IPR024079 Metallopeptidase, catalytic domain superfamily GO:0008237 TON_0963 684219c8837c766246c7d4fd36b3b705 380 PIRSF PIRSF002825 1 335 3.0E-51 T 23-10-2018 IPR026045 Ferric binding protein TON_0963 684219c8837c766246c7d4fd36b3b705 380 Gene3D G3DSA:3.40.190.10 30 306 1.2E-117 T 23-10-2018 TON_0963 684219c8837c766246c7d4fd36b3b705 380 TIGRFAM TIGR01254 sfuA: ABC transporter periplasmic binding protein, thiB subfamily 25 330 2.0E-98 T 23-10-2018 IPR005948 Thiamine/thiamin pyrophosphate-binding periplasmic protein, ABC transporter GO:0015888|GO:0030975 TON_0963 684219c8837c766246c7d4fd36b3b705 380 SUPERFAMILY SSF53850 24 332 3.34E-81 T 23-10-2018 TON_0963 684219c8837c766246c7d4fd36b3b705 380 Pfam PF13416 Bacterial extracellular solute-binding protein 44 304 1.7E-33 T 23-10-2018 IPR006059 Bacterial extracellular solute-binding protein TON_0963 684219c8837c766246c7d4fd36b3b705 380 Gene3D G3DSA:3.40.190.10 131 331 1.2E-117 T 23-10-2018 TON_0963 684219c8837c766246c7d4fd36b3b705 380 TIGRFAM TIGR04288 CGP_CTERM: CGP-CTERM domain 360 379 4.6E-8 T 23-10-2018 IPR027552 CGP-CTERM domain TON_1793 c7f7222b8ddda41a97dc60b4b4ff679e 415 SUPERFAMILY SSF161098 6 67 2.4E-6 T 23-10-2018 IPR035906 MetI-like superfamily TON_1793 c7f7222b8ddda41a97dc60b4b4ff679e 415 SUPERFAMILY SSF161098 191 414 4.84E-50 T 23-10-2018 IPR035906 MetI-like superfamily TON_1793 c7f7222b8ddda41a97dc60b4b4ff679e 415 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 213 401 1.1E-14 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TON_1793 c7f7222b8ddda41a97dc60b4b4ff679e 415 Gene3D G3DSA:1.10.3720.10 2 80 5.4E-8 T 23-10-2018 IPR035906 MetI-like superfamily TON_1793 c7f7222b8ddda41a97dc60b4b4ff679e 415 Gene3D G3DSA:1.10.3720.10 173 405 1.3E-43 T 23-10-2018 IPR035906 MetI-like superfamily TON_1081 65348c67fc319e6a81761eae9ef50df7 246 SUPERFAMILY SSF52540 1 235 1.94E-64 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_1081 65348c67fc319e6a81761eae9ef50df7 246 PIRSF PIRSF003092 1 243 9.6E-58 T 23-10-2018 IPR025501 ATP binding protein MinD TON_1081 65348c67fc319e6a81761eae9ef50df7 246 Pfam PF13614 AAA domain 3 145 1.1E-27 T 23-10-2018 IPR025669 AAA domain TON_1081 65348c67fc319e6a81761eae9ef50df7 246 TIGRFAM TIGR01969 minD_arch: cell division ATPase MinD 3 237 5.5E-100 T 23-10-2018 IPR010224 ATP binding protein MinD, archaea TON_1081 65348c67fc319e6a81761eae9ef50df7 246 Pfam PF00142 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family 157 234 4.7E-7 T 23-10-2018 IPR000392 NifH/frxC family GO:0005524|GO:0016491|GO:0055114 TON_1081 65348c67fc319e6a81761eae9ef50df7 246 Gene3D G3DSA:3.40.50.300 1 235 1.0E-75 T 23-10-2018 TON_1596 b602651f297ae0216277e9a00480fcf4 162 Pfam PF02915 Rubrerythrin 18 152 3.7E-15 T 23-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 TON_1596 b602651f297ae0216277e9a00480fcf4 162 Gene3D G3DSA:1.20.1260.10 8 158 8.9E-31 T 23-10-2018 IPR012347 Ferritin-like TON_1596 b602651f297ae0216277e9a00480fcf4 162 SUPERFAMILY SSF47240 15 158 4.51E-25 T 23-10-2018 IPR009078 Ferritin-like superfamily TON_1974 4bbb302b9448bf1df2e2c7e25ce27e04 179 Pfam PF04458 Protein of unknown function (DUF505) 2 126 2.2E-22 T 23-10-2018 IPR007548 Protein of unknown function DUF505 TON_1488 06d8e56f0332134640fc46a553905c90 297 Gene3D G3DSA:3.40.1190.20 6 289 1.2E-61 T 23-10-2018 IPR029056 Ribokinase-like TON_1488 06d8e56f0332134640fc46a553905c90 297 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 229 242 - T 23-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 TON_1488 06d8e56f0332134640fc46a553905c90 297 SUPERFAMILY SSF53613 5 276 1.25E-62 T 23-10-2018 IPR029056 Ribokinase-like TON_1488 06d8e56f0332134640fc46a553905c90 297 PRINTS PR00990 Ribokinase signature 167 182 7.2E-9 T 23-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 TON_1488 06d8e56f0332134640fc46a553905c90 297 PRINTS PR00990 Ribokinase signature 9 30 7.2E-9 T 23-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 TON_1488 06d8e56f0332134640fc46a553905c90 297 PRINTS PR00990 Ribokinase signature 106 119 7.2E-9 T 23-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 TON_1488 06d8e56f0332134640fc46a553905c90 297 PRINTS PR00990 Ribokinase signature 36 55 7.2E-9 T 23-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 TON_1488 06d8e56f0332134640fc46a553905c90 297 PRINTS PR00990 Ribokinase signature 199 210 7.2E-9 T 23-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 TON_1488 06d8e56f0332134640fc46a553905c90 297 Pfam PF00294 pfkB family carbohydrate kinase 9 274 2.8E-41 T 23-10-2018 IPR011611 Carbohydrate kinase PfkB TON_0056 ae9ae55960b970f984039647c02131ae 278 SUPERFAMILY SSF63380 2 91 7.05E-20 T 23-10-2018 IPR017938 Riboflavin synthase-like beta-barrel TON_0056 ae9ae55960b970f984039647c02131ae 278 SUPERFAMILY SSF52343 88 248 1.7E-31 T 23-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain TON_0056 ae9ae55960b970f984039647c02131ae 278 PIRSF PIRSF006816 1 255 3.2E-69 T 23-10-2018 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 TON_0056 ae9ae55960b970f984039647c02131ae 278 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 212 249 4.8E-13 T 23-10-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain TON_0056 ae9ae55960b970f984039647c02131ae 278 Gene3D G3DSA:2.40.30.10 1 91 8.9E-21 T 23-10-2018 TON_0056 ae9ae55960b970f984039647c02131ae 278 Gene3D G3DSA:3.40.50.80 99 203 3.8E-39 T 23-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain TON_1031 ef47875015a0fbd915dc8d00e916bde6 520 Pfam PF00361 Proton-conducting membrane transporter 132 439 3.9E-60 T 23-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_1031 ef47875015a0fbd915dc8d00e916bde6 520 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 249 273 1.8E-5 T 23-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_1031 ef47875015a0fbd915dc8d00e916bde6 520 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 136 155 1.8E-5 T 23-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_1031 ef47875015a0fbd915dc8d00e916bde6 520 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 397 423 1.8E-5 T 23-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_1031 ef47875015a0fbd915dc8d00e916bde6 520 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 74 115 9.9E-7 T 23-10-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_1266 0647e3503e787cb3bfb00aff9bf2e7f0 168 Gene3D G3DSA:3.30.70.20 47 94 3.2E-12 T 23-10-2018 TON_1266 0647e3503e787cb3bfb00aff9bf2e7f0 168 SUPERFAMILY SSF54862 6 137 7.48E-19 T 23-10-2018 TON_1266 0647e3503e787cb3bfb00aff9bf2e7f0 168 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 74 85 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TON_1266 0647e3503e787cb3bfb00aff9bf2e7f0 168 Pfam PF00037 4Fe-4S binding domain 67 88 1.4E-7 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TON_1616 1f29fd009a7e71b285b516c47dc230bb 184 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 3 179 1.8E-63 T 23-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 TON_1616 1f29fd009a7e71b285b516c47dc230bb 184 Gene3D G3DSA:3.90.950.10 1 184 1.8E-72 T 23-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like TON_1616 1f29fd009a7e71b285b516c47dc230bb 184 Hamap MF_01405 dITP/XTP pyrophosphatase. 1 181 42.396 T 23-10-2018 IPR020922 dITP/XTP pyrophosphatase GO:0009143|GO:0017111 KEGG: 00230+3.6.1.66 TON_1616 1f29fd009a7e71b285b516c47dc230bb 184 SUPERFAMILY SSF52972 1 182 5.23E-62 T 23-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like TON_1616 1f29fd009a7e71b285b516c47dc230bb 184 Pfam PF01725 Ham1 family 3 178 4.0E-49 T 23-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 TON_0767 2869690d1781e9c8d3aa66dfe3a0cc02 118 Gene3D G3DSA:2.40.50.140 7 118 5.8E-41 T 23-10-2018 TON_0767 2869690d1781e9c8d3aa66dfe3a0cc02 118 ProDom PD005579 INITIATION FACTOR TRANSLATION 1A BIOSYNTHESIS EUKARYOTIC EIF-1A AIF-1A EIF-4C 1A 49 106 3.0E-26 T 23-10-2018 IPR001253 Translation initiation factor 1A (eIF-1A) GO:0003743|GO:0006413 TON_0767 2869690d1781e9c8d3aa66dfe3a0cc02 118 SUPERFAMILY SSF50249 3 110 7.71E-32 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold TON_0767 2869690d1781e9c8d3aa66dfe3a0cc02 118 Pfam PF01176 Translation initiation factor 1A / IF-1 28 91 2.4E-20 T 23-10-2018 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 TON_0767 2869690d1781e9c8d3aa66dfe3a0cc02 118 SMART SM00652 24 107 6.7E-43 T 23-10-2018 IPR001253 Translation initiation factor 1A (eIF-1A) GO:0003743|GO:0006413 TON_0767 2869690d1781e9c8d3aa66dfe3a0cc02 118 ProSitePatterns PS01262 Eukaryotic initiation factor 1A signature. 37 59 - T 23-10-2018 IPR018104 Translation initiation factor 1A (eIF-1A), conserved site GO:0003743|GO:0006413 TON_0767 2869690d1781e9c8d3aa66dfe3a0cc02 118 TIGRFAM TIGR00523 eIF-1A: translation initiation factor eIF-1A 15 106 1.1E-34 T 23-10-2018 IPR001253 Translation initiation factor 1A (eIF-1A) GO:0003743|GO:0006413 TON_0767 2869690d1781e9c8d3aa66dfe3a0cc02 118 Hamap MF_00216 Translation initiation factor 1A [eif1a]. 13 107 28.19 T 23-10-2018 IPR001253 Translation initiation factor 1A (eIF-1A) GO:0003743|GO:0006413 TON_0379 ceb64cb86329419fe609ae43156fd99e 95 Hamap MF_00261 DNA-directed RNA polymerase subunit L [rpoL]. 1 89 19.68 T 23-10-2018 IPR022905 DNA-directed RNA polymerase subunit L (Rpo11) GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TON_0379 ceb64cb86329419fe609ae43156fd99e 95 Pfam PF13656 RNA polymerase Rpb3/Rpb11 dimerisation domain 13 84 1.7E-20 T 23-10-2018 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 TON_0379 ceb64cb86329419fe609ae43156fd99e 95 Gene3D G3DSA:3.30.1360.10 1 93 1.5E-33 T 23-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TON_0379 ceb64cb86329419fe609ae43156fd99e 95 ProSitePatterns PS01154 RNA polymerases L / 13 to 16 Kd subunits signature. 17 48 - T 23-10-2018 IPR008193 DNA-directed RNA polymerase Rpb11, 13-16kDa subunit, conserved site GO:0003677|GO:0003899|GO:0006351 TON_0379 ceb64cb86329419fe609ae43156fd99e 95 SUPERFAMILY SSF55257 1 90 2.49E-24 T 23-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TON_0050 a6f2c9d666b49050727bc4706a38ba9d 281 PIRSF PIRSF004961 1 281 4.8E-123 T 23-10-2018 IPR011589 Protein of unknown function UCP004961 TON_0050 a6f2c9d666b49050727bc4706a38ba9d 281 SUPERFAMILY SSF51556 1 278 5.02E-33 T 23-10-2018 IPR032466 Metal-dependent hydrolase TON_0050 a6f2c9d666b49050727bc4706a38ba9d 281 Pfam PF01026 TatD related DNase 5 275 8.5E-31 T 23-10-2018 IPR001130 TatD family GO:0016788 TON_0050 a6f2c9d666b49050727bc4706a38ba9d 281 Gene3D G3DSA:3.20.20.140 3 281 4.0E-29 T 23-10-2018 TON_0050 a6f2c9d666b49050727bc4706a38ba9d 281 ProDom PD038341 HYDROLASE COFACTOR MOLYBDENUM BIOSYNTHESIS METAL-DEPENDENT DEOXYRIBONUCLEASE PREDICTED TATD-RELATED TVG0313409 A 114 280 1.0E-81 T 23-10-2018 TON_0132 d77499847ff4745209c6dedb40f14867 291 Gene3D G3DSA:3.40.830.10 1 290 2.3E-68 T 23-10-2018 TON_0132 d77499847ff4745209c6dedb40f14867 291 Hamap MF_00055 MEMO1 family protein . 1 290 60.261 T 23-10-2018 IPR002737 MEMO1 family Reactome: R-HSA-6785631 TON_0132 d77499847ff4745209c6dedb40f14867 291 Pfam PF01875 Memo-like protein 5 288 1.4E-72 T 23-10-2018 IPR002737 MEMO1 family Reactome: R-HSA-6785631 TON_0132 d77499847ff4745209c6dedb40f14867 291 SUPERFAMILY SSF53213 55 288 9.94E-9 T 23-10-2018 TON_0132 d77499847ff4745209c6dedb40f14867 291 TIGRFAM TIGR04336 AmmeMemoSam_B: AmmeMemoRadiSam system protein B 3 289 2.6E-91 T 23-10-2018 TON_0795 575c6edac7e5135b0294b0ae6190a731 123 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 8 117 5.1E-25 T 23-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 TON_0795 575c6edac7e5135b0294b0ae6190a731 123 TIGRFAM TIGR00494 crcB: protein CrcB 8 121 1.4E-28 T 23-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 TON_0795 575c6edac7e5135b0294b0ae6190a731 123 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 6 122 19.569 T 23-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 TON_0803 aca2823659fd1177f248e432e4cd00fe 378 SUPERFAMILY SSF103473 8 372 1.96E-30 T 23-10-2018 IPR036259 MFS transporter superfamily TON_0803 aca2823659fd1177f248e432e4cd00fe 378 Gene3D G3DSA:1.20.1250.20 7 375 5.8E-28 T 23-10-2018 TON_0803 aca2823659fd1177f248e432e4cd00fe 378 Pfam PF07690 Major Facilitator Superfamily 12 332 5.2E-15 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TON_0182 7d61a21d06e479ad9c8196700dad1a6b 105 Gene3D G3DSA:1.10.10.1410 1 58 2.9E-31 T 23-10-2018 IPR038716 Ribosomal protein P1/P2, N-terminal domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0182 7d61a21d06e479ad9c8196700dad1a6b 105 Hamap MF_01478 50S ribosomal protein L12 [rpl12]. 1 102 14.556 T 23-10-2018 IPR027534 Ribosomal protein L12 family GO:0003735|GO:0005622|GO:0005840|GO:0006414 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0182 7d61a21d06e479ad9c8196700dad1a6b 105 Pfam PF00428 60s Acidic ribosomal protein 16 104 4.7E-20 T 23-10-2018 TON_0182 7d61a21d06e479ad9c8196700dad1a6b 105 TIGRFAM TIGR03685 ribo_P1_arch: 50S ribosomal protein P1 1 105 2.3E-42 T 23-10-2018 IPR022295 Ribosomal protein L12, archaea GO:0003735|GO:0005840|GO:0006414 TON_0305 17d58bff6a46ae22f2f40b58ebcd543b 441 TIGRFAM TIGR03385 CoA_CoA_reduc: CoA-disulfide reductase 5 436 5.1E-185 T 23-10-2018 IPR017758 Coenzyme A disulphide reductase GO:0003756|GO:0050451|GO:0050660|GO:0050661|GO:0055114 TON_0305 17d58bff6a46ae22f2f40b58ebcd543b 441 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 149 174 4.3E-22 T 23-10-2018 TON_0305 17d58bff6a46ae22f2f40b58ebcd543b 441 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 233 247 4.3E-22 T 23-10-2018 TON_0305 17d58bff6a46ae22f2f40b58ebcd543b 441 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 384 399 4.3E-22 T 23-10-2018 TON_0305 17d58bff6a46ae22f2f40b58ebcd543b 441 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 274 281 4.3E-22 T 23-10-2018 TON_0305 17d58bff6a46ae22f2f40b58ebcd543b 441 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 4.3E-22 T 23-10-2018 TON_0305 17d58bff6a46ae22f2f40b58ebcd543b 441 SUPERFAMILY SSF55424 320 438 2.58E-31 T 23-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 TON_0305 17d58bff6a46ae22f2f40b58ebcd543b 441 Gene3D G3DSA:3.50.50.60 43 241 9.1E-115 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TON_0305 17d58bff6a46ae22f2f40b58ebcd543b 441 Gene3D G3DSA:3.50.50.60 320 441 9.9E-45 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TON_0305 17d58bff6a46ae22f2f40b58ebcd543b 441 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 326 427 1.2E-19 T 23-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 TON_0305 17d58bff6a46ae22f2f40b58ebcd543b 441 SUPERFAMILY SSF51905 3 344 3.13E-48 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TON_0305 17d58bff6a46ae22f2f40b58ebcd543b 441 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 8.0E-28 T 23-10-2018 TON_0305 17d58bff6a46ae22f2f40b58ebcd543b 441 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 259 281 8.0E-28 T 23-10-2018 TON_0305 17d58bff6a46ae22f2f40b58ebcd543b 441 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 102 120 8.0E-28 T 23-10-2018 TON_0305 17d58bff6a46ae22f2f40b58ebcd543b 441 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 149 167 8.0E-28 T 23-10-2018 TON_0305 17d58bff6a46ae22f2f40b58ebcd543b 441 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 232 248 8.0E-28 T 23-10-2018 TON_0305 17d58bff6a46ae22f2f40b58ebcd543b 441 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 296 3.7E-58 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TON_0305 17d58bff6a46ae22f2f40b58ebcd543b 441 Gene3D G3DSA:3.50.50.60 5 314 9.1E-115 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TON_1171 982d707b74638291438a088c9af9e3fb 189 SUPERFAMILY SSF88697 2 103 6.09E-23 T 23-10-2018 IPR015947 PUA-like superfamily TON_1171 982d707b74638291438a088c9af9e3fb 189 SMART SM01022 4 104 1.1E-26 T 23-10-2018 IPR007374 ASCH domain TON_1171 982d707b74638291438a088c9af9e3fb 189 Pfam PF04266 ASCH domain 4 104 7.1E-19 T 23-10-2018 IPR007374 ASCH domain TON_0573 5ed0de119b7e62f61f00fceaf5dded55 243 Pfam PF01925 Sulfite exporter TauE/SafE 8 241 6.5E-56 T 23-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 TON_1914 6e95c1e4e729cf742d458a4af272790b 178 SUPERFAMILY SSF50324 1 176 3.14E-67 T 23-10-2018 IPR036649 Inorganic pyrophosphatase superfamily GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 TON_1914 6e95c1e4e729cf742d458a4af272790b 178 Gene3D G3DSA:3.90.80.10 1 178 6.3E-75 T 23-10-2018 IPR036649 Inorganic pyrophosphatase superfamily GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 TON_1914 6e95c1e4e729cf742d458a4af272790b 178 Hamap MF_00209 Inorganic pyrophosphatase [ppa]. 15 171 36.206 T 23-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 TON_1914 6e95c1e4e729cf742d458a4af272790b 178 Pfam PF00719 Inorganic pyrophosphatase 20 171 1.1E-57 T 23-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 TON_1914 6e95c1e4e729cf742d458a4af272790b 178 ProSitePatterns PS00387 Inorganic pyrophosphatase signature. 66 72 - T 23-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 TON_0702 7bd46ef6523d8f84b2d252c322c64bef 348 PRINTS PR00419 Adrenodoxin reductase family signature 169 183 3.3E-15 T 23-10-2018 TON_0702 7bd46ef6523d8f84b2d252c322c64bef 348 PRINTS PR00419 Adrenodoxin reductase family signature 39 52 3.3E-15 T 23-10-2018 TON_0702 7bd46ef6523d8f84b2d252c322c64bef 348 PRINTS PR00419 Adrenodoxin reductase family signature 16 38 3.3E-15 T 23-10-2018 TON_0702 7bd46ef6523d8f84b2d252c322c64bef 348 Gene3D G3DSA:3.40.50.720 11 134 1.7E-18 T 23-10-2018 TON_0702 7bd46ef6523d8f84b2d252c322c64bef 348 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 16 311 5.8E-29 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TON_0702 7bd46ef6523d8f84b2d252c322c64bef 348 SUPERFAMILY SSF51971 14 270 1.29E-54 T 23-10-2018 TON_0702 7bd46ef6523d8f84b2d252c322c64bef 348 Gene3D G3DSA:3.50.50.60 135 269 8.4E-24 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TON_0560 e33fdd6928aa5e6976b5f794a646a262 405 Gene3D G3DSA:3.30.300.340 18 286 6.8E-171 T 23-10-2018 TON_0560 e33fdd6928aa5e6976b5f794a646a262 405 Gene3D G3DSA:3.30.300.10 30 154 6.8E-171 T 23-10-2018 TON_0560 e33fdd6928aa5e6976b5f794a646a262 405 Hamap MF_00136 S-adenosylmethionine synthase [mat]. 5 405 52.287 T 23-10-2018 IPR002795 S-adenosylmethionine synthetase, archaea GO:0004478|GO:0005524|GO:0006730 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912 TON_0560 e33fdd6928aa5e6976b5f794a646a262 405 Gene3D G3DSA:3.30.300.280 16 398 6.8E-171 T 23-10-2018 TON_0560 e33fdd6928aa5e6976b5f794a646a262 405 Pfam PF01941 S-adenosylmethionine synthetase (AdoMet synthetase) 6 401 1.6E-180 T 23-10-2018 IPR027790 S-adenosylmethionine synthase KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912 TON_0560 e33fdd6928aa5e6976b5f794a646a262 405 ProDom PD011777 SYNTHETASE TRANSFERASE METHIONINE ADENOSYLTRANSFERASE S-ADENOSYLMETHIONINE NUCLEOTIDE-BINDING METABOLISM ATP-BINDING MAGNESIUM ONE-CARBON 21 405 0.0 T 23-10-2018 TON_1037 e175275f8fea34f3f7c54752b65910b5 217 SMART SM00382 25 199 3.0E-4 T 23-10-2018 IPR003593 AAA+ ATPase domain TON_1037 e175275f8fea34f3f7c54752b65910b5 217 ProSitePatterns PS00211 ABC transporters family signature. 124 138 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TON_1037 e175275f8fea34f3f7c54752b65910b5 217 SUPERFAMILY SSF52540 2 213 1.38E-46 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_1037 e175275f8fea34f3f7c54752b65910b5 217 Pfam PF00005 ABC transporter 17 152 2.7E-21 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TON_1037 e175275f8fea34f3f7c54752b65910b5 217 Gene3D G3DSA:3.40.50.300 1 217 2.5E-48 T 23-10-2018 TON_1943 2faed47a8a9d9a82d25ee76d5281d4e4 136 Pfam PF04900 Fcf1 31 128 5.4E-7 T 23-10-2018 IPR006984 rRNA-processing protein Fcf1/Utp23 GO:0032040 TON_1943 2faed47a8a9d9a82d25ee76d5281d4e4 136 SUPERFAMILY SSF88723 5 128 4.32E-23 T 23-10-2018 IPR029060 PIN-like domain superfamily TON_1943 2faed47a8a9d9a82d25ee76d5281d4e4 136 Gene3D G3DSA:3.40.50.1010 5 134 3.7E-30 T 23-10-2018 TON_1943 2faed47a8a9d9a82d25ee76d5281d4e4 136 SMART SM00670 5 111 1.7E-8 T 23-10-2018 IPR002716 PIN domain TON_0527 af4cc8815ea61ec51ec54b8ea29ea935 127 Gene3D G3DSA:3.30.1330.40 1 127 6.7E-53 T 23-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 TON_0527 af4cc8815ea61ec51ec54b8ea29ea935 127 TIGRFAM TIGR00004 TIGR00004: reactive intermediate/imine deaminase 2 126 3.6E-52 T 23-10-2018 IPR006056 RidA family Reactome: R-HSA-8849175 TON_0527 af4cc8815ea61ec51ec54b8ea29ea935 127 SUPERFAMILY SSF55298 1 127 1.24E-45 T 23-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 TON_0527 af4cc8815ea61ec51ec54b8ea29ea935 127 Pfam PF01042 Endoribonuclease L-PSP 7 126 4.8E-44 T 23-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 TON_0527 af4cc8815ea61ec51ec54b8ea29ea935 127 ProSitePatterns PS01094 Uncharacterized protein family UPF0076 signature. 103 121 - T 23-10-2018 IPR019897 RidA, conserved site Reactome: R-HSA-8849175 TON_1859 0146f11ff73508f12664c822d6bbe87e 159 Gene3D G3DSA:3.40.50.2000 1 155 3.2E-27 T 23-10-2018 TON_1859 0146f11ff73508f12664c822d6bbe87e 159 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 1 148 1.3E-20 T 23-10-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-5633231 TON_1859 0146f11ff73508f12664c822d6bbe87e 159 SUPERFAMILY SSF53756 2 134 2.69E-13 T 23-10-2018 TON_1204 94c4ce9c2d4ef119d76971fa6b0e3985 341 Gene3D G3DSA:1.10.10.10 244 340 7.5E-6 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TON_1204 94c4ce9c2d4ef119d76971fa6b0e3985 341 Pfam PF04283 Chemotaxis signal transduction system protein F from archaea 98 228 1.4E-13 T 23-10-2018 IPR007381 Chemotaxis signal transduction system protein F TON_1201 08ba2775b355f234a3274d1a9c903977 162 SUPERFAMILY SSF64438 3 156 2.65E-48 T 23-10-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic TON_1201 08ba2775b355f234a3274d1a9c903977 162 Gene3D G3DSA:3.30.1330.200 2 161 6.5E-54 T 23-10-2018 IPR038592 CheD-like superfamily TON_1201 08ba2775b355f234a3274d1a9c903977 162 Hamap MF_01440 Chemoreceptor glutamine deamidase CheD [cheD]. 3 155 26.339 T 23-10-2018 IPR005659 Chemoreceptor glutamine deamidase CheD GO:0006935|GO:0050568 TON_1201 08ba2775b355f234a3274d1a9c903977 162 Pfam PF03975 CheD chemotactic sensory transduction 47 151 3.0E-34 T 23-10-2018 IPR005659 Chemoreceptor glutamine deamidase CheD GO:0006935|GO:0050568 TON_0052 95cb5164f8fc8815038b5dfe82f79dff 415 SUPERFAMILY SSF56762 2 411 1.13E-92 T 23-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_0052 95cb5164f8fc8815038b5dfe82f79dff 415 Gene3D G3DSA:1.10.645.10 1 411 6.4E-99 T 23-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_0052 95cb5164f8fc8815038b5dfe82f79dff 415 ProSitePatterns PS00508 Nickel-dependent hydrogenases large subunit signature 2. 402 411 - T 23-10-2018 IPR018194 Nickel-dependent hydrogenase, large subunit, nickel binding site GO:0008901|GO:0016151|GO:0055114 TON_0052 95cb5164f8fc8815038b5dfe82f79dff 415 Pfam PF00374 Nickel-dependent hydrogenase 224 411 2.7E-17 T 23-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 TON_0052 95cb5164f8fc8815038b5dfe82f79dff 415 Pfam PF00374 Nickel-dependent hydrogenase 39 123 4.5E-13 T 23-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 TON_1945 7ce57ba7a0b9cb14def8544f4fa76ee7 125 ProSitePatterns PS00578 Ribosomal protein S6e signature. 63 74 - T 23-10-2018 IPR018282 Ribosomal protein S6e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-166208|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_1945 7ce57ba7a0b9cb14def8544f4fa76ee7 125 Pfam PF01092 Ribosomal protein S6e 4 124 2.2E-36 T 23-10-2018 IPR001377 Ribosomal protein S6e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-166208|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_1945 7ce57ba7a0b9cb14def8544f4fa76ee7 125 SMART SM01405 4 124 7.8E-51 T 23-10-2018 IPR001377 Ribosomal protein S6e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-166208|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_1945 7ce57ba7a0b9cb14def8544f4fa76ee7 125 Hamap MF_00512 30S ribosomal protein S6e [rps6e]. 2 125 18.785 T 23-10-2018 IPR020924 Ribosomal protein S6e, archaeal GO:0003735|GO:0005840|GO:0006412 TON_1766 287e1b5544398cebe60d0e74e7df7c1b 486 SUPERFAMILY SSF161098 274 467 6.54E-23 T 23-10-2018 IPR035906 MetI-like superfamily TON_1766 287e1b5544398cebe60d0e74e7df7c1b 486 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 298 485 1.6E-28 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TON_1766 287e1b5544398cebe60d0e74e7df7c1b 486 Gene3D G3DSA:1.10.3720.10 270 485 2.8E-22 T 23-10-2018 IPR035906 MetI-like superfamily TON_0746 82708e346b36311333137337ae6db399 214 Pfam PF12705 PD-(D/E)XK nuclease superfamily 80 208 4.8E-5 T 23-10-2018 IPR038726 PD-(D/E)XK endonuclease-like domain, AddAB-type TON_0746 82708e346b36311333137337ae6db399 214 TIGRFAM TIGR00372 cas4: CRISPR-associated protein Cas4 16 209 1.8E-29 T 23-10-2018 IPR013343 CRISPR-associated protein Cas4 TON_0746 82708e346b36311333137337ae6db399 214 Gene3D G3DSA:3.90.320.10 2 211 1.2E-23 T 23-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal TON_0636 9c333b84fd9f9428020fa3e555819057 879 Gene3D G3DSA:2.60.40.10 393 483 8.6E-8 T 23-10-2018 IPR013783 Immunoglobulin-like fold TON_0636 9c333b84fd9f9428020fa3e555819057 879 Gene3D G3DSA:3.40.50.880 651 875 1.9E-12 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like TON_0636 9c333b84fd9f9428020fa3e555819057 879 SUPERFAMILY SSF52317 648 878 2.98E-26 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like TON_0636 9c333b84fd9f9428020fa3e555819057 879 Pfam PF09822 ABC-type uncharacterized transport system 654 754 1.2E-9 T 23-10-2018 IPR019196 ABC-type uncharacterised transport system Reactome: R-HSA-5610787|Reactome: R-HSA-5620924 TON_1439 b3de26885c270c3ccb10cef27dfaf536 520 SUPERFAMILY SSF48208 331 505 8.51E-10 T 23-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 TON_1439 b3de26885c270c3ccb10cef27dfaf536 520 Pfam PF06662 D-glucuronyl C5-epimerase C-terminus 331 498 4.0E-41 T 23-10-2018 IPR010598 D-glucuronyl C5-epimerase, C-terminal KEGG: 00534+5.1.3.17|MetaCyc: PWY-6558|Reactome: R-HSA-2022928 TON_1370 23e1d1d68a81d3b59a216213402d23b5 121 Pfam PF03965 Penicillinase repressor 19 111 6.9E-16 T 23-10-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 TON_1370 23e1d1d68a81d3b59a216213402d23b5 121 Gene3D G3DSA:1.10.10.10 19 85 2.2E-13 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TON_1370 23e1d1d68a81d3b59a216213402d23b5 121 SUPERFAMILY SSF46785 17 117 9.43E-16 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TON_0887 014f6ed3600d8c539f7e851baa1bfc14 240 SUPERFAMILY SSF56784 1 208 7.85E-12 T 23-10-2018 IPR036412 HAD-like superfamily TON_0235 b9743f91100c24ab185657ac8524114e 94 Pfam PF00935 Ribosomal protein L44 16 92 4.7E-26 T 23-10-2018 IPR000552 Ribosomal protein L44e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0235 b9743f91100c24ab185657ac8524114e 94 Gene3D G3DSA:3.10.450.80 1 93 8.7E-31 T 23-10-2018 TON_0235 b9743f91100c24ab185657ac8524114e 94 ProSitePatterns PS01172 Ribosomal protein L44e signature. 60 71 - T 23-10-2018 IPR000552 Ribosomal protein L44e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0235 b9743f91100c24ab185657ac8524114e 94 ProDom PD002841 RIBOSOMAL RIBONUCLEOPROTEIN 60S L44 L44E L41 RESISTANCE 50S ANTIBIOTIC CYCLOHEXIMIDE 9 93 2.0E-40 T 23-10-2018 IPR000552 Ribosomal protein L44e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0235 b9743f91100c24ab185657ac8524114e 94 SUPERFAMILY SSF57829 1 93 2.15E-30 T 23-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 TON_0235 b9743f91100c24ab185657ac8524114e 94 Hamap MF_01476 50S ribosomal protein L44e [rpl44e]. 1 92 24.828 T 23-10-2018 IPR000552 Ribosomal protein L44e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_1546 84969f1f2e84d680187474ef89a68fe6 75 Gene3D G3DSA:3.30.70.920 1 74 8.7E-27 T 23-10-2018 TON_1546 84969f1f2e84d680187474ef89a68fe6 75 Pfam PF01037 Lrp/AsnC ligand binding domain 9 74 2.3E-18 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain TON_1546 84969f1f2e84d680187474ef89a68fe6 75 SUPERFAMILY SSF54909 1 74 9.52E-18 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel TON_1454 90eb6545410cc089d7bcbd10f5453bd4 453 Gene3D G3DSA:3.30.2290.10 1 188 2.8E-20 T 23-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal TON_1454 90eb6545410cc089d7bcbd10f5453bd4 453 PIRSF PIRSF004919 1 453 1.8E-164 T 23-10-2018 IPR025502 TldD TON_1454 90eb6545410cc089d7bcbd10f5453bd4 453 SUPERFAMILY SSF111283 2 447 1.57E-114 T 23-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 TON_1454 90eb6545410cc089d7bcbd10f5453bd4 453 Pfam PF01523 Putative modulator of DNA gyrase 19 307 6.5E-63 T 23-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 TON_1300 85d0eeed794d869f8a05ee8fedc09eb2 226 ProSitePatterns PS00566 Fibrillarin signature. 98 112 - T 23-10-2018 IPR020813 Fibrillarin, conserved site GO:0003723|GO:0006364|GO:0008168 TON_1300 85d0eeed794d869f8a05ee8fedc09eb2 226 PRINTS PR00052 Fibrillarin signature 23 42 7.0E-79 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 TON_1300 85d0eeed794d869f8a05ee8fedc09eb2 226 PRINTS PR00052 Fibrillarin signature 204 225 7.0E-79 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 TON_1300 85d0eeed794d869f8a05ee8fedc09eb2 226 PRINTS PR00052 Fibrillarin signature 73 94 7.0E-79 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 TON_1300 85d0eeed794d869f8a05ee8fedc09eb2 226 PRINTS PR00052 Fibrillarin signature 123 152 7.0E-79 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 TON_1300 85d0eeed794d869f8a05ee8fedc09eb2 226 PRINTS PR00052 Fibrillarin signature 153 182 7.0E-79 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 TON_1300 85d0eeed794d869f8a05ee8fedc09eb2 226 PRINTS PR00052 Fibrillarin signature 46 65 7.0E-79 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 TON_1300 85d0eeed794d869f8a05ee8fedc09eb2 226 PRINTS PR00052 Fibrillarin signature 98 115 7.0E-79 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 TON_1300 85d0eeed794d869f8a05ee8fedc09eb2 226 SMART SM01206 3 226 3.6E-145 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 TON_1300 85d0eeed794d869f8a05ee8fedc09eb2 226 Pfam PF01269 Fibrillarin 4 224 6.0E-101 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 TON_1300 85d0eeed794d869f8a05ee8fedc09eb2 226 PIRSF PIRSF006540 1 226 2.1E-100 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 TON_1300 85d0eeed794d869f8a05ee8fedc09eb2 226 SUPERFAMILY SSF53335 3 225 4.99E-60 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TON_1300 85d0eeed794d869f8a05ee8fedc09eb2 226 Gene3D G3DSA:3.40.50.150 51 226 2.2E-74 T 23-10-2018 TON_1300 85d0eeed794d869f8a05ee8fedc09eb2 226 Hamap MF_00351 Fibrillarin-like rRNA/tRNA 2'-O-methyltransferase [flpA]. 16 226 44.146 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 TON_1300 85d0eeed794d869f8a05ee8fedc09eb2 226 Gene3D G3DSA:3.30.200.20 1 50 1.7E-25 T 23-10-2018 TON_0939 bbe82e35020608dfd1eeeb13b263feff 233 Gene3D G3DSA:3.60.15.10 2 228 6.9E-45 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TON_0939 bbe82e35020608dfd1eeeb13b263feff 233 SMART SM00849 27 215 3.2E-40 T 23-10-2018 IPR001279 Metallo-beta-lactamase TON_0939 bbe82e35020608dfd1eeeb13b263feff 233 Pfam PF00753 Metallo-beta-lactamase superfamily 28 215 7.5E-27 T 23-10-2018 IPR001279 Metallo-beta-lactamase TON_0939 bbe82e35020608dfd1eeeb13b263feff 233 SUPERFAMILY SSF56281 13 233 7.99E-46 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TON_1838 2feaeb789f34ba15dcc1529337090914 73 Gene3D G3DSA:3.40.50.300 2 73 7.1E-11 T 23-10-2018 TON_1838 2feaeb789f34ba15dcc1529337090914 73 SUPERFAMILY SSF52540 7 63 1.69E-9 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_1090 cb5c9b3d8155fc4f53ca8ca0afebf51e 457 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 243 421 1.7E-39 T 23-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 TON_1090 cb5c9b3d8155fc4f53ca8ca0afebf51e 457 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 109 3.9E-28 T 23-10-2018 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: R-HSA-2408557|Reactome: R-HSA-379716 TON_1090 cb5c9b3d8155fc4f53ca8ca0afebf51e 457 SUPERFAMILY SSF46589 1 115 4.87E-28 T 23-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 TON_1090 cb5c9b3d8155fc4f53ca8ca0afebf51e 457 SUPERFAMILY SSF55681 154 445 2.9E-89 T 23-10-2018 TON_1090 cb5c9b3d8155fc4f53ca8ca0afebf51e 457 TIGRFAM TIGR00414 serS: serine--tRNA ligase 1 438 3.6E-163 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 TON_1090 cb5c9b3d8155fc4f53ca8ca0afebf51e 457 PRINTS PR00981 Seryl-tRNA synthetase signature 285 297 1.3E-32 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 TON_1090 cb5c9b3d8155fc4f53ca8ca0afebf51e 457 PRINTS PR00981 Seryl-tRNA synthetase signature 372 388 1.3E-32 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 TON_1090 cb5c9b3d8155fc4f53ca8ca0afebf51e 457 PRINTS PR00981 Seryl-tRNA synthetase signature 354 370 1.3E-32 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 TON_1090 cb5c9b3d8155fc4f53ca8ca0afebf51e 457 PRINTS PR00981 Seryl-tRNA synthetase signature 297 310 1.3E-32 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 TON_1090 cb5c9b3d8155fc4f53ca8ca0afebf51e 457 PRINTS PR00981 Seryl-tRNA synthetase signature 337 350 1.3E-32 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 TON_1090 cb5c9b3d8155fc4f53ca8ca0afebf51e 457 PIRSF PIRSF001529 1 447 7.3E-155 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 TON_1090 cb5c9b3d8155fc4f53ca8ca0afebf51e 457 Gene3D G3DSA:1.10.287.40 1 107 1.3E-34 T 23-10-2018 TON_1090 cb5c9b3d8155fc4f53ca8ca0afebf51e 457 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 443 41.806 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 TON_1090 cb5c9b3d8155fc4f53ca8ca0afebf51e 457 Gene3D G3DSA:3.30.930.10 108 455 2.0E-137 T 23-10-2018 TON_0396 0eb9cffeeb0479423c6612ee95ff9a4c 500 Gene3D G3DSA:3.30.930.10 193 499 2.3E-90 T 23-10-2018 TON_0396 0eb9cffeeb0479423c6612ee95ff9a4c 500 SUPERFAMILY SSF46785 3 111 2.38E-6 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TON_0396 0eb9cffeeb0479423c6612ee95ff9a4c 500 Pfam PF01409 tRNA synthetases class II core domain (F) 224 495 8.2E-82 T 23-10-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 TON_0396 0eb9cffeeb0479423c6612ee95ff9a4c 500 Gene3D G3DSA:1.10.10.10 3 80 8.4E-6 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TON_0396 0eb9cffeeb0479423c6612ee95ff9a4c 500 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 182 496 9.8E-93 T 23-10-2018 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 TON_0396 0eb9cffeeb0479423c6612ee95ff9a4c 500 SUPERFAMILY SSF55681 225 496 1.03E-58 T 23-10-2018 TON_0396 0eb9cffeeb0479423c6612ee95ff9a4c 500 Hamap MF_00282 Phenylalanine--tRNA ligase alpha subunit [pheS]. 2 497 38.147 T 23-10-2018 IPR022917 Phenylalanine-tRNA ligase alpha subunit, bacterial/archaeal GO:0004826 KEGG: 00970+6.1.1.20 TON_1913 7fc817afb1b373fdbb52fd4fc954434c 188 Gene3D G3DSA:3.30.1490.120 1 81 2.9E-32 T 23-10-2018 IPR036898 RNA polymerase Rpb7-like, N-terminal domain superfamily GO:0003899|GO:0006351 TON_1913 7fc817afb1b373fdbb52fd4fc954434c 188 Pfam PF00575 S1 RNA binding domain 78 150 1.7E-15 T 23-10-2018 IPR003029 S1 domain GO:0003676 TON_1913 7fc817afb1b373fdbb52fd4fc954434c 188 SMART SM00316 80 166 8.2E-18 T 23-10-2018 IPR022967 RNA-binding domain, S1 TON_1913 7fc817afb1b373fdbb52fd4fc954434c 188 Pfam PF03876 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 8 77 1.9E-19 T 23-10-2018 IPR005576 RNA polymerase Rpb7, N-terminal GO:0003899|GO:0006351 TON_1913 7fc817afb1b373fdbb52fd4fc954434c 188 Gene3D G3DSA:2.40.50.140 82 188 1.8E-32 T 23-10-2018 TON_1913 7fc817afb1b373fdbb52fd4fc954434c 188 SUPERFAMILY SSF88798 1 78 1.27E-21 T 23-10-2018 IPR036898 RNA polymerase Rpb7-like, N-terminal domain superfamily GO:0003899|GO:0006351 TON_1913 7fc817afb1b373fdbb52fd4fc954434c 188 SUPERFAMILY SSF50249 80 179 5.22E-25 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold TON_1913 7fc817afb1b373fdbb52fd4fc954434c 188 TIGRFAM TIGR00448 rpoE: DNA-directed RNA polymerase 1 179 5.8E-67 T 23-10-2018 IPR004519 DNA-directed RNA polymerase, subunit E/RPC8 GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-1834949|Reactome: R-HSA-73780|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071 TON_0310 093c99db46670466f05653f4560904d2 821 Gene3D G3DSA:3.40.50.12610 379 499 4.9E-8 T 23-10-2018 TON_0310 093c99db46670466f05653f4560904d2 821 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 69 219 1.4E-14 T 23-10-2018 IPR038731 Glycosyltransferase RgtA/B/C/D-like TON_0310 093c99db46670466f05653f4560904d2 821 SUPERFAMILY SSF48239 529 779 1.05E-12 T 23-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid TON_1653 84971e5cdda20883145fa39c938a8cf5 424 Hamap MF_01281 5'-deoxyadenosine deaminase [dadD]. 2 424 48.568 T 23-10-2018 IPR023512 Deaminase MtaD/DadD GO:0019239 TON_1653 84971e5cdda20883145fa39c938a8cf5 424 SUPERFAMILY SSF51338 1 423 2.16E-37 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 TON_1653 84971e5cdda20883145fa39c938a8cf5 424 Pfam PF01979 Amidohydrolase family 51 397 3.7E-77 T 23-10-2018 IPR006680 Amidohydrolase-related GO:0016787 TON_1653 84971e5cdda20883145fa39c938a8cf5 424 SUPERFAMILY SSF51556 54 347 2.3E-106 T 23-10-2018 IPR032466 Metal-dependent hydrolase TON_1653 84971e5cdda20883145fa39c938a8cf5 424 Gene3D G3DSA:2.30.40.10 4 415 1.1E-156 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 TON_1653 84971e5cdda20883145fa39c938a8cf5 424 Gene3D G3DSA:3.20.20.140 55 344 1.1E-156 T 23-10-2018 TON_0946 4131b1059e07b7683507170dd813ba0d 404 Gene3D G3DSA:3.40.640.10 70 294 3.8E-141 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TON_0946 4131b1059e07b7683507170dd813ba0d 404 Gene3D G3DSA:3.90.1150.10 22 397 3.8E-141 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TON_0946 4131b1059e07b7683507170dd813ba0d 404 SUPERFAMILY SSF53383 6 399 2.29E-103 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TON_0946 4131b1059e07b7683507170dd813ba0d 404 Pfam PF00155 Aminotransferase class I and II 35 396 1.1E-41 T 23-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 TON_1224 776f1dbe4664c315a7e48abeb77b1297 127 Gene3D G3DSA:2.40.50.140 63 127 7.7E-16 T 23-10-2018 TON_1224 776f1dbe4664c315a7e48abeb77b1297 127 Pfam PF01957 NfeD-like C-terminal, partner-binding 17 124 4.1E-13 T 23-10-2018 IPR002810 NfeD-like, C-terminal domain TON_1224 776f1dbe4664c315a7e48abeb77b1297 127 SUPERFAMILY SSF141322 61 124 1.27E-9 T 23-10-2018 TON_0987 872dfc0e0bab8975ef2c78cd96157d37 672 SUPERFAMILY SSF56300 130 391 3.99E-29 T 23-10-2018 TON_0987 872dfc0e0bab8975ef2c78cd96157d37 672 TIGRFAM TIGR04288 CGP_CTERM: CGP-CTERM domain 652 671 1.0E-7 T 23-10-2018 IPR027552 CGP-CTERM domain TON_0987 872dfc0e0bab8975ef2c78cd96157d37 672 Pfam PF00149 Calcineurin-like phosphoesterase 130 370 5.5E-9 T 23-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 TON_0987 872dfc0e0bab8975ef2c78cd96157d37 672 Gene3D G3DSA:3.60.21.10 186 378 3.0E-17 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like TON_0987 872dfc0e0bab8975ef2c78cd96157d37 672 Gene3D G3DSA:2.60.40.10 535 644 7.4E-5 T 23-10-2018 IPR013783 Immunoglobulin-like fold TON_1147 6f85e9447625fdedcdbcff40935f462c 232 Pfam PF04240 Carotenoid biosynthesis protein 26 216 1.4E-26 T 23-10-2018 IPR007354 Carotene biosynthesis associated membrane protein TON_0316 f67822579630fc4265db35971a1bc3da 396 Pfam PF01494 FAD binding domain 6 322 2.1E-16 T 23-10-2018 IPR002938 FAD-binding domain GO:0071949 TON_0316 f67822579630fc4265db35971a1bc3da 396 Gene3D G3DSA:3.30.9.10 72 359 5.1E-107 T 23-10-2018 TON_0316 f67822579630fc4265db35971a1bc3da 396 TIGRFAM TIGR02032 GG-red-SF: geranylgeranyl reductase family 6 304 3.7E-76 T 23-10-2018 IPR011777 Geranylgeranyl reductase family GO:0016628|GO:0055114 TON_0316 f67822579630fc4265db35971a1bc3da 396 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 269 284 2.8E-10 T 23-10-2018 TON_0316 f67822579630fc4265db35971a1bc3da 396 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 7 29 2.8E-10 T 23-10-2018 TON_0316 f67822579630fc4265db35971a1bc3da 396 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 147 162 2.8E-10 T 23-10-2018 TON_0316 f67822579630fc4265db35971a1bc3da 396 Hamap MF_01287 Digeranylgeranylglycerophospholipid reductase. 4 390 39.284 T 23-10-2018 IPR023590 Digeranylgeranylglycerophospholipid reductase GO:0016628|GO:0045550|GO:0046467|GO:0055114 KEGG: 00564+1.3.7.11|MetaCyc: PWY-6349 TON_0316 f67822579630fc4265db35971a1bc3da 396 Gene3D G3DSA:3.50.50.60 6 341 5.1E-107 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TON_0316 f67822579630fc4265db35971a1bc3da 396 SUPERFAMILY SSF51905 4 337 1.13E-38 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TON_0898 a971ffadf4e74af3f5d8083e281f5dc3 432 TIGRFAM TIGR02549 CRISPR_DxTHG: CRISPR-associated DxTHG motif protein 125 145 2.5E-5 T 23-10-2018 IPR013383 CRISPR-associated protein DxTHG, conserved site TON_0898 a971ffadf4e74af3f5d8083e281f5dc3 432 SUPERFAMILY SSF160980 1 422 1.44E-80 T 23-10-2018 TON_0898 a971ffadf4e74af3f5d8083e281f5dc3 432 TIGRFAM TIGR01897 cas_MJ1666: CRISPR-associated protein, MJ1666 family 1 394 1.3E-71 T 23-10-2018 IPR010171 CRISPR-associated protein, MJ1666 TON_0898 a971ffadf4e74af3f5d8083e281f5dc3 432 Pfam PF09455 CRISPR-associated (Cas) DxTHG family 4 384 8.5E-13 T 23-10-2018 IPR019016 CRISPR-associated DxTHG protein TON_0832 f8ea957b5bcf7b3015bbb4ac6f226298 283 SUPERFAMILY SSF52540 2 217 1.64E-58 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_0832 f8ea957b5bcf7b3015bbb4ac6f226298 283 ProSitePatterns PS00211 ABC transporters family signature. 130 144 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TON_0832 f8ea957b5bcf7b3015bbb4ac6f226298 283 Pfam PF00005 ABC transporter 20 157 1.2E-28 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TON_0832 f8ea957b5bcf7b3015bbb4ac6f226298 283 SMART SM00382 28 213 7.2E-10 T 23-10-2018 IPR003593 AAA+ ATPase domain TON_0832 f8ea957b5bcf7b3015bbb4ac6f226298 283 Gene3D G3DSA:3.40.50.300 1 233 2.9E-61 T 23-10-2018 TON_0148 120be4940d27f9027dd5e4e99245236e 335 Pfam PF04087 Domain of unknown function (DUF389) 146 285 2.8E-27 T 23-10-2018 IPR005240 Protein of unknown function DUF389 TON_0148 120be4940d27f9027dd5e4e99245236e 335 TIGRFAM TIGR00341 TIGR00341: TIGR00341 family protein 102 328 7.0E-40 T 23-10-2018 TON_1160 632abb387163aad2d8d5972368702962 395 SUPERFAMILY SSF103473 15 381 2.49E-28 T 23-10-2018 IPR036259 MFS transporter superfamily TON_1160 632abb387163aad2d8d5972368702962 395 Gene3D G3DSA:1.20.1250.20 18 381 5.6E-23 T 23-10-2018 TON_0716 d8ca2399e6ffe711cd69d92fd378aba8 312 TIGRFAM TIGR00446 nop2p: NOL1/NOP2/sun family putative RNA methylase 39 306 1.1E-91 T 23-10-2018 IPR011023 Nop2p GO:0003723|GO:0006364|GO:0008757 Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 TON_0716 d8ca2399e6ffe711cd69d92fd378aba8 312 Gene3D G3DSA:3.30.70.3130 5 96 5.4E-17 T 23-10-2018 TON_0716 d8ca2399e6ffe711cd69d92fd378aba8 312 Gene3D G3DSA:3.40.50.150 101 312 5.1E-71 T 23-10-2018 TON_0716 d8ca2399e6ffe711cd69d92fd378aba8 312 Pfam PF01189 16S rRNA methyltransferase RsmB/F 101 304 1.5E-52 T 23-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 TON_0716 d8ca2399e6ffe711cd69d92fd378aba8 312 Pfam PF17125 N-terminal domain of 16S rRNA methyltransferase RsmF 12 97 6.6E-17 T 23-10-2018 IPR031341 Ribosomal RNA small subunit methyltransferase F, N-terminal Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 TON_0716 d8ca2399e6ffe711cd69d92fd378aba8 312 SUPERFAMILY SSF53335 21 306 1.13E-61 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TON_0716 d8ca2399e6ffe711cd69d92fd378aba8 312 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 112 122 9.1E-24 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TON_0716 d8ca2399e6ffe711cd69d92fd378aba8 312 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 83 97 9.1E-24 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TON_0716 d8ca2399e6ffe711cd69d92fd378aba8 312 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 228 244 9.1E-24 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TON_0716 d8ca2399e6ffe711cd69d92fd378aba8 312 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 178 190 9.1E-24 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TON_0716 d8ca2399e6ffe711cd69d92fd378aba8 312 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 289 306 9.1E-24 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TON_0448 ed763f1950491568adccd8079e90e447 108 Gene3D G3DSA:1.10.10.1220 1 88 3.5E-42 T 23-10-2018 TON_1724 bab9a402b248e5bd1f0e642ca97a8be7 254 SMART SM00155 199 226 9.2E-4 T 23-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 TON_1724 bab9a402b248e5bd1f0e642ca97a8be7 254 Pfam PF13091 PLD-like domain 124 251 2.5E-23 T 23-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 TON_1724 bab9a402b248e5bd1f0e642ca97a8be7 254 SUPERFAMILY SSF56024 118 252 1.01E-29 T 23-10-2018 TON_1724 bab9a402b248e5bd1f0e642ca97a8be7 254 Gene3D G3DSA:3.30.870.10 83 254 9.7E-35 T 23-10-2018 TON_1537 abea3186eaa0966d4a2951505bcb43a7 66 Pfam PF01954 Protein of unknown function DUF104 1 54 8.5E-13 T 23-10-2018 IPR008203 Uncharacterised protein family UPF0165 TON_1537 abea3186eaa0966d4a2951505bcb43a7 66 Gene3D G3DSA:4.10.1150.10 1 65 5.1E-7 T 23-10-2018 IPR024069 AF2212-like domain superfamily TON_1537 abea3186eaa0966d4a2951505bcb43a7 66 SUPERFAMILY SSF141694 1 47 3.14E-13 T 23-10-2018 TON_1058 4c062b883e93dcb8b1d56f7dd7552acb 268 PRINTS PR00721 Stomatin signature 76 97 9.3E-74 T 23-10-2018 IPR001972 Stomatin family GO:0016020 TON_1058 4c062b883e93dcb8b1d56f7dd7552acb 268 PRINTS PR00721 Stomatin signature 199 222 9.3E-74 T 23-10-2018 IPR001972 Stomatin family GO:0016020 TON_1058 4c062b883e93dcb8b1d56f7dd7552acb 268 PRINTS PR00721 Stomatin signature 131 154 9.3E-74 T 23-10-2018 IPR001972 Stomatin family GO:0016020 TON_1058 4c062b883e93dcb8b1d56f7dd7552acb 268 PRINTS PR00721 Stomatin signature 111 128 9.3E-74 T 23-10-2018 IPR001972 Stomatin family GO:0016020 TON_1058 4c062b883e93dcb8b1d56f7dd7552acb 268 PRINTS PR00721 Stomatin signature 29 51 9.3E-74 T 23-10-2018 IPR001972 Stomatin family GO:0016020 TON_1058 4c062b883e93dcb8b1d56f7dd7552acb 268 PRINTS PR00721 Stomatin signature 174 195 9.3E-74 T 23-10-2018 IPR001972 Stomatin family GO:0016020 TON_1058 4c062b883e93dcb8b1d56f7dd7552acb 268 PRINTS PR00721 Stomatin signature 155 173 9.3E-74 T 23-10-2018 IPR001972 Stomatin family GO:0016020 TON_1058 4c062b883e93dcb8b1d56f7dd7552acb 268 SMART SM00244 22 179 4.1E-71 T 23-10-2018 IPR001107 Band 7 domain TON_1058 4c062b883e93dcb8b1d56f7dd7552acb 268 Gene3D G3DSA:3.30.479.30 50 181 6.4E-51 T 23-10-2018 TON_1058 4c062b883e93dcb8b1d56f7dd7552acb 268 SUPERFAMILY SSF117892 53 186 1.7E-46 T 23-10-2018 IPR036013 Band 7/SPFH domain superfamily TON_1058 4c062b883e93dcb8b1d56f7dd7552acb 268 Pfam PF01145 SPFH domain / Band 7 family 26 196 1.2E-37 T 23-10-2018 IPR001107 Band 7 domain TON_0332 2d8504e55f2ac7f82e8213387dc2581a 264 Gene3D G3DSA:3.30.870.10 122 264 1.1E-77 T 23-10-2018 TON_0332 2d8504e55f2ac7f82e8213387dc2581a 264 SUPERFAMILY SSF46785 10 96 6.96E-7 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TON_0332 2d8504e55f2ac7f82e8213387dc2581a 264 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 10 77 1.7E-18 T 23-10-2018 IPR002831 Transcription regulator TrmB, N-terminal TON_0332 2d8504e55f2ac7f82e8213387dc2581a 264 Gene3D G3DSA:1.10.10.10 1 75 3.2E-21 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TON_1434 56a37ebba906bae0090d2f623693edba 137 Pfam PF01894 Uncharacterised protein family UPF0047 20 134 3.6E-36 T 23-10-2018 IPR001602 Uncharacterised protein family UPF0047 TON_1434 56a37ebba906bae0090d2f623693edba 137 SUPERFAMILY SSF111038 1 137 1.83E-44 T 23-10-2018 IPR035917 YjbQ-like superfamily TON_1434 56a37ebba906bae0090d2f623693edba 137 Gene3D G3DSA:2.60.120.460 1 137 6.0E-51 T 23-10-2018 IPR035917 YjbQ-like superfamily TON_1434 56a37ebba906bae0090d2f623693edba 137 PIRSF PIRSF004681 1 137 3.2E-38 T 23-10-2018 IPR001602 Uncharacterised protein family UPF0047 TON_1434 56a37ebba906bae0090d2f623693edba 137 TIGRFAM TIGR00149 TIGR00149_YjbQ: secondary thiamine-phosphate synthase enzyme 8 137 8.3E-39 T 23-10-2018 IPR001602 Uncharacterised protein family UPF0047 TON_0186 939d33f7f55a6058e5a1967e0bd33439 424 Pfam PF04055 Radical SAM superfamily 168 338 2.4E-25 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TON_0186 939d33f7f55a6058e5a1967e0bd33439 424 Gene3D G3DSA:3.80.30.20 163 390 6.1E-37 T 23-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe TON_0186 939d33f7f55a6058e5a1967e0bd33439 424 SUPERFAMILY SSF102114 152 377 2.09E-39 T 23-10-2018 TON_0186 939d33f7f55a6058e5a1967e0bd33439 424 Pfam PF02310 B12 binding domain 24 112 1.0E-8 T 23-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 TON_0186 939d33f7f55a6058e5a1967e0bd33439 424 Gene3D G3DSA:3.40.50.280 2 127 2.6E-25 T 23-10-2018 TON_0186 939d33f7f55a6058e5a1967e0bd33439 424 SMART SM00729 164 382 6.8E-48 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TON_0186 939d33f7f55a6058e5a1967e0bd33439 424 TIGRFAM TIGR04013 B12_SAM_MJ_1487: B12-binding domain/radical SAM domain protein, MJ_1487 family 4 392 8.4E-142 T 23-10-2018 IPR023980 Conserved hypothetical protein CHP04013, B12-binding/radical SAM-type TON_0257 77c16ad142153c8ea6c6fa0dc061b4c8 232 SUPERFAMILY SSF143555 12 180 2.09E-48 T 23-10-2018 TON_0257 77c16ad142153c8ea6c6fa0dc061b4c8 232 Gene3D G3DSA:3.30.1330.130 3 173 1.3E-41 T 23-10-2018 TON_0257 77c16ad142153c8ea6c6fa0dc061b4c8 232 PIRSF PIRSF006578 2 217 3.4E-48 T 23-10-2018 IPR026328 Formylmethanofuran dehydrogenase, subunit E TON_0257 77c16ad142153c8ea6c6fa0dc061b4c8 232 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 182 216 7.9E-7 T 23-10-2018 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 TON_0257 77c16ad142153c8ea6c6fa0dc061b4c8 232 Pfam PF02663 FmdE, Molybdenum formylmethanofuran dehydrogenase operon 23 165 6.5E-35 T 23-10-2018 IPR003814 Formylmethanofuran dehydrogenase, subunit E domain TON_0045 3745fb03c6a04fe7ba653cf6d81b8e63 170 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 1 151 2.1E-33 T 23-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 TON_0045 3745fb03c6a04fe7ba653cf6d81b8e63 170 Gene3D G3DSA:3.60.21.10 1 159 7.9E-53 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like TON_0045 3745fb03c6a04fe7ba653cf6d81b8e63 170 ProSitePatterns PS01269 Uncharacterized protein family UPF0025 signature. 108 132 - T 23-10-2018 IPR020935 Phosphodiesterase YfcE, conserved site TON_0045 3745fb03c6a04fe7ba653cf6d81b8e63 170 SUPERFAMILY SSF56300 1 161 1.36E-39 T 23-10-2018 TON_0045 3745fb03c6a04fe7ba653cf6d81b8e63 170 TIGRFAM TIGR00040 yfcE: phosphodiesterase, MJ0936 family 1 155 2.6E-39 T 23-10-2018 IPR000979 Phosphodiesterase MJ0936/Vps29 Reactome: R-HSA-3238698 TON_1256 ee8ce7270c29c46a4cd6fb1205d5651d 416 SUPERFAMILY SSF55307 238 352 1.88E-34 T 23-10-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 TON_1256 ee8ce7270c29c46a4cd6fb1205d5651d 416 Pfam PF12327 FtsZ family, C-terminal domain 253 347 9.9E-24 T 23-10-2018 IPR024757 Cell division protein FtsZ, C-terminal TON_1256 ee8ce7270c29c46a4cd6fb1205d5651d 416 ProSitePatterns PS01134 FtsZ protein signature 1. 68 102 - T 23-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 TON_1256 ee8ce7270c29c46a4cd6fb1205d5651d 416 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 37 205 3.8E-43 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TON_1256 ee8ce7270c29c46a4cd6fb1205d5651d 416 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 34 357 6.8E-111 T 23-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 TON_1256 ee8ce7270c29c46a4cd6fb1205d5651d 416 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 33 383 33.447 T 23-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 TON_1256 ee8ce7270c29c46a4cd6fb1205d5651d 416 ProSitePatterns PS01135 FtsZ protein signature 2. 121 142 - T 23-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 TON_1256 ee8ce7270c29c46a4cd6fb1205d5651d 416 SMART SM00864 37 236 6.7E-84 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TON_1256 ee8ce7270c29c46a4cd6fb1205d5651d 416 SUPERFAMILY SSF52490 33 235 1.01E-56 T 23-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 TON_1256 ee8ce7270c29c46a4cd6fb1205d5651d 416 PRINTS PR00423 Cell division protein FtsZ signature 220 242 1.3E-35 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TON_1256 ee8ce7270c29c46a4cd6fb1205d5651d 416 PRINTS PR00423 Cell division protein FtsZ signature 122 142 1.3E-35 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TON_1256 ee8ce7270c29c46a4cd6fb1205d5651d 416 PRINTS PR00423 Cell division protein FtsZ signature 158 179 1.3E-35 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TON_1256 ee8ce7270c29c46a4cd6fb1205d5651d 416 PRINTS PR00423 Cell division protein FtsZ signature 243 264 1.3E-35 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TON_1256 ee8ce7270c29c46a4cd6fb1205d5651d 416 Gene3D G3DSA:3.40.50.1440 35 347 3.2E-99 T 23-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 TON_1256 ee8ce7270c29c46a4cd6fb1205d5651d 416 SMART SM00865 238 355 2.4E-37 T 23-10-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-380320 TON_1380 83a4da85498e7d714c254bd33fc40a6d 533 Gene3D G3DSA:3.40.50.300 1 267 3.6E-25 T 23-10-2018 TON_1380 83a4da85498e7d714c254bd33fc40a6d 533 Gene3D G3DSA:3.40.50.300 367 519 1.9E-16 T 23-10-2018 TON_1380 83a4da85498e7d714c254bd33fc40a6d 533 Pfam PF13361 UvrD-like helicase C-terminal domain 163 498 3.9E-14 T 23-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 TON_1380 83a4da85498e7d714c254bd33fc40a6d 533 SUPERFAMILY SSF52540 9 511 7.79E-54 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_1261 22d027cb028df1eb574b73f50e3c6a0b 401 Pfam PF07690 Major Facilitator Superfamily 19 355 4.2E-20 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TON_1261 22d027cb028df1eb574b73f50e3c6a0b 401 Gene3D G3DSA:1.20.1250.20 2 392 7.3E-18 T 23-10-2018 TON_1261 22d027cb028df1eb574b73f50e3c6a0b 401 SUPERFAMILY SSF103473 3 390 2.75E-33 T 23-10-2018 IPR036259 MFS transporter superfamily TON_0140 3c6197d4a2088f03a99ea4be1748ac44 269 SUPERFAMILY SSF53335 28 208 1.67E-17 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TON_0140 3c6197d4a2088f03a99ea4be1748ac44 269 Pfam PF13649 Methyltransferase domain 51 145 1.8E-7 T 23-10-2018 TON_0140 3c6197d4a2088f03a99ea4be1748ac44 269 Gene3D G3DSA:3.40.50.150 26 217 1.2E-20 T 23-10-2018 TON_0128 43d1149ba4b2b1c348753ef6696529ce 267 Gene3D G3DSA:3.40.50.1580 1 266 3.4E-100 T 23-10-2018 TON_0128 43d1149ba4b2b1c348753ef6696529ce 267 Hamap MF_01963 S-methyl-5'-thioadenosine phosphorylase [mtnP]. 2 266 43.533 T 23-10-2018 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112|Reactome: R-HSA-8950505 TON_0128 43d1149ba4b2b1c348753ef6696529ce 267 ProSitePatterns PS01240 Purine and other phosphorylases family 2 signature. 48 88 - T 23-10-2018 IPR018099 Purine phosphorylase, family 2, conserved site GO:0016763 TON_0128 43d1149ba4b2b1c348753ef6696529ce 267 Pfam PF01048 Phosphorylase superfamily 3 246 3.9E-55 T 23-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 TON_0128 43d1149ba4b2b1c348753ef6696529ce 267 SUPERFAMILY SSF53167 1 264 7.72E-96 T 23-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 TON_0128 43d1149ba4b2b1c348753ef6696529ce 267 TIGRFAM TIGR01694 MTAP: methylthioadenosine phosphorylase 4 247 6.1E-96 T 23-10-2018 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112|Reactome: R-HSA-8950505 TON_0165 dce747bef9ad78b69a9229c5c60e81c8 648 SMART SM00322 102 169 2.9E-4 T 23-10-2018 IPR004087 K Homology domain GO:0003676 TON_0165 dce747bef9ad78b69a9229c5c60e81c8 648 Pfam PF17214 KH domain 9 76 2.8E-27 T 23-10-2018 IPR033769 KH domain, archaeal TON_0165 dce747bef9ad78b69a9229c5c60e81c8 648 Gene3D G3DSA:3.30.300.20 72 142 8.4E-65 T 23-10-2018 IPR015946 K homology domain-like, alpha/beta TON_0165 dce747bef9ad78b69a9229c5c60e81c8 648 Pfam PF10996 Beta-Casp domain 433 556 4.5E-24 T 23-10-2018 IPR022712 Beta-Casp domain TON_0165 dce747bef9ad78b69a9229c5c60e81c8 648 Gene3D G3DSA:3.60.15.10 191 627 7.3E-165 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TON_0165 dce747bef9ad78b69a9229c5c60e81c8 648 Pfam PF16661 Metallo-beta-lactamase superfamily domain 205 351 7.3E-9 T 23-10-2018 IPR001279 Metallo-beta-lactamase TON_0165 dce747bef9ad78b69a9229c5c60e81c8 648 TIGRFAM TIGR03675 arCOG00543: arCOG00543 universal archaeal KH-domain/beta-lactamase-domain protein 13 647 1.7E-299 T 23-10-2018 IPR019975 KH-domain/beta-lactamase-domain protein, archaea TON_0165 dce747bef9ad78b69a9229c5c60e81c8 648 Gene3D G3DSA:3.40.50.10890 401 588 7.3E-165 T 23-10-2018 TON_0165 dce747bef9ad78b69a9229c5c60e81c8 648 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 576 639 8.2E-19 T 23-10-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain TON_0165 dce747bef9ad78b69a9229c5c60e81c8 648 Gene3D G3DSA:3.30.300.230 17 176 8.4E-65 T 23-10-2018 TON_0165 dce747bef9ad78b69a9229c5c60e81c8 648 SUPERFAMILY SSF54814 94 139 2.88E-5 T 23-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 TON_0165 dce747bef9ad78b69a9229c5c60e81c8 648 SUPERFAMILY SSF56281 183 647 8.44E-132 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TON_0165 dce747bef9ad78b69a9229c5c60e81c8 648 SMART SM00849 198 428 4.2E-26 T 23-10-2018 IPR001279 Metallo-beta-lactamase TON_0165 dce747bef9ad78b69a9229c5c60e81c8 648 SMART SM01027 433 557 3.2E-57 T 23-10-2018 IPR022712 Beta-Casp domain TON_1020 ebda6b84ffb53fe93248b147bd122ab1 64 Pfam PF10133 Predicted RNA-binding protein 1 57 7.9E-14 T 23-10-2018 IPR019300 RNA-binding protein, predicted TON_1180 d333b1eda014bfba52085cea67b4a8c9 232 Gene3D G3DSA:3.40.50.300 3 232 6.6E-45 T 23-10-2018 TON_1180 d333b1eda014bfba52085cea67b4a8c9 232 SUPERFAMILY SSF52540 4 221 4.49E-27 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_1180 d333b1eda014bfba52085cea67b4a8c9 232 Pfam PF06745 KaiC 15 220 7.7E-18 T 23-10-2018 IPR014774 KaiC-like domain TON_1244 bbedd03bd3ed9ad5600f113e9c7e34d0 436 Pfam PF07282 Putative transposase DNA-binding domain 318 387 8.2E-21 T 23-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal TON_1244 bbedd03bd3ed9ad5600f113e9c7e34d0 436 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 268 345 3.0E-8 T 23-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal TON_1244 bbedd03bd3ed9ad5600f113e9c7e34d0 436 Pfam PF01385 Probable transposase 178 298 1.5E-36 T 23-10-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 TON_0489 78ab43d92d3127d78df6f87f7e3e3b90 190 SUPERFAMILY SSF56770 6 155 6.28E-52 T 23-10-2018 TON_0489 78ab43d92d3127d78df6f87f7e3e3b90 190 TIGRFAM TIGR01957 nuoB_fam: NADH-quinone oxidoreductase, B subunit 8 142 1.7E-42 T 23-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_0489 78ab43d92d3127d78df6f87f7e3e3b90 190 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 25 136 2.6E-19 T 23-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_0489 78ab43d92d3127d78df6f87f7e3e3b90 190 Gene3D G3DSA:3.40.50.12280 2 163 1.2E-49 T 23-10-2018 TON_1699 a5e2831feaa60b50e95097698df440c7 145 Gene3D G3DSA:2.160.10.10 9 143 2.5E-34 T 23-10-2018 TON_1699 a5e2831feaa60b50e95097698df440c7 145 SUPERFAMILY SSF51161 4 141 4.02E-36 T 23-10-2018 IPR011004 Trimeric LpxA-like superfamily TON_1699 a5e2831feaa60b50e95097698df440c7 145 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 78 111 4.2E-9 T 23-10-2018 IPR001451 Hexapeptide repeat TON_1699 a5e2831feaa60b50e95097698df440c7 145 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 86 114 - T 23-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 TON_1593 99a826f5bacbd63748bfd3cae24127de 426 Pfam PF00374 Nickel-dependent hydrogenase 47 114 1.1E-14 T 23-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 TON_1593 99a826f5bacbd63748bfd3cae24127de 426 SUPERFAMILY SSF56762 18 381 9.29E-104 T 23-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_1593 99a826f5bacbd63748bfd3cae24127de 426 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 122 381 1.2E-58 T 23-10-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_1593 99a826f5bacbd63748bfd3cae24127de 426 Gene3D G3DSA:1.10.645.20 9 381 7.9E-121 T 23-10-2018 IPR038290 NADH-quinone oxidoreductase, subunit D superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_1010 5a8ad52a0198cc982b043358f7d79d8c 202 Gene3D G3DSA:3.40.109.10 1 201 1.5E-48 T 23-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 TON_1010 5a8ad52a0198cc982b043358f7d79d8c 202 Pfam PF00881 Nitroreductase family 7 181 1.3E-33 T 23-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 TON_1010 5a8ad52a0198cc982b043358f7d79d8c 202 SUPERFAMILY SSF55469 4 201 1.15E-43 T 23-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 TON_1872 76c1e4a4f13fa61e5698795d8ba1363b 376 Pfam PF01497 Periplasmic binding protein 79 324 1.8E-30 T 23-10-2018 IPR002491 ABC transporter periplasmic binding domain TON_1872 76c1e4a4f13fa61e5698795d8ba1363b 376 Gene3D G3DSA:3.40.50.1980 48 375 9.7E-71 T 23-10-2018 TON_1872 76c1e4a4f13fa61e5698795d8ba1363b 376 SUPERFAMILY SSF53807 63 374 1.06E-59 T 23-10-2018 TON_0376 b906b581f13e8e1ce791ed4bd87eb1eb 627 Gene3D G3DSA:3.30.930.10 204 495 7.4E-64 T 23-10-2018 TON_0376 b906b581f13e8e1ce791ed4bd87eb1eb 627 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 35 607 29.123 T 23-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 TON_0376 b906b581f13e8e1ce791ed4bd87eb1eb 627 SUPERFAMILY SSF52954 505 607 2.57E-31 T 23-10-2018 TON_0376 b906b581f13e8e1ce791ed4bd87eb1eb 627 SUPERFAMILY SSF55681 208 490 2.68E-58 T 23-10-2018 TON_0376 b906b581f13e8e1ce791ed4bd87eb1eb 627 Gene3D G3DSA:3.40.50.800 505 608 5.0E-34 T 23-10-2018 IPR036621 Anticodon-binding domain superfamily TON_0376 b906b581f13e8e1ce791ed4bd87eb1eb 627 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 290 493 1.0E-18 T 23-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 TON_0376 b906b581f13e8e1ce791ed4bd87eb1eb 627 Gene3D G3DSA:3.50.80.10 1 139 6.2E-58 T 23-10-2018 IPR023509 D-aminoacyl-tRNA deacylase-like superfamily TON_0376 b906b581f13e8e1ce791ed4bd87eb1eb 627 Pfam PF08915 Archaea-specific editing domain of threonyl-tRNA synthetase 1 139 2.2E-56 T 23-10-2018 IPR015011 Threonyl-tRNA synthetase, editing domain, archaea GO:0004829|GO:0005524|GO:0005737|GO:0008270 KEGG: 00970+6.1.1.3 TON_0376 b906b581f13e8e1ce791ed4bd87eb1eb 627 ProDom PD016189 SYNTHETASE LIGASE THREONYL-TRNA AMINOACYL-TRNA NUCLEOTIDE-BINDING BIOSYNTHESIS ATP-BINDING ZINC METAL-BINDING THRRS 1 139 5.0E-60 T 23-10-2018 IPR015011 Threonyl-tRNA synthetase, editing domain, archaea GO:0004829|GO:0005524|GO:0005737|GO:0008270 KEGG: 00970+6.1.1.3 TON_0376 b906b581f13e8e1ce791ed4bd87eb1eb 627 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 25 604 7.0E-177 T 23-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 TON_0376 b906b581f13e8e1ce791ed4bd87eb1eb 627 Pfam PF03129 Anticodon binding domain 514 603 1.0E-24 T 23-10-2018 IPR004154 Anticodon-binding TON_0376 b906b581f13e8e1ce791ed4bd87eb1eb 627 PRINTS PR01047 Threonyl-tRNA synthetase signature 329 352 1.5E-32 T 23-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 TON_0376 b906b581f13e8e1ce791ed4bd87eb1eb 627 PRINTS PR01047 Threonyl-tRNA synthetase signature 472 485 1.5E-32 T 23-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 TON_0376 b906b581f13e8e1ce791ed4bd87eb1eb 627 PRINTS PR01047 Threonyl-tRNA synthetase signature 295 323 1.5E-32 T 23-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 TON_0376 b906b581f13e8e1ce791ed4bd87eb1eb 627 PRINTS PR01047 Threonyl-tRNA synthetase signature 507 519 1.5E-32 T 23-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 TON_0376 b906b581f13e8e1ce791ed4bd87eb1eb 627 PRINTS PR01047 Threonyl-tRNA synthetase signature 429 457 1.5E-32 T 23-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 TON_0897 20843b735ca82588914a814490afe4dc 397 TIGRFAM TIGR01899 cas_TM1807_csm5: CRISPR type III-A/MTUBE-associated RAMP protein Csm5 5 395 5.4E-81 T 23-10-2018 IPR010173 CRISPR-associated protein, TM1807 TON_0897 20843b735ca82588914a814490afe4dc 397 Pfam PF03787 RAMP superfamily 5 342 5.6E-21 T 23-10-2018 IPR005537 CRISPR type III-associated RAMP protein TON_0905 eb36cfcc6cefbe35c4bfe66010b240d6 566 Pfam PF02554 Carbon starvation protein CstA 1 364 3.1E-112 T 23-10-2018 IPR003706 CstA, N-terminal domain GO:0009267|GO:0016020 TON_0905 eb36cfcc6cefbe35c4bfe66010b240d6 566 Pfam PF13722 5TM C-terminal transporter carbon starvation CstA 402 520 3.5E-31 T 23-10-2018 IPR025299 CstA, C-terminal domain TON_1017 f2b83241c658b01733a72ccc9ac7d02b 212 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 101 112 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TON_1017 f2b83241c658b01733a72ccc9ac7d02b 212 Pfam PF13247 4Fe-4S dicluster domain 62 156 3.8E-25 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TON_1017 f2b83241c658b01733a72ccc9ac7d02b 212 Pfam PF12837 4Fe-4S binding domain 14 32 7.0E-6 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TON_1017 f2b83241c658b01733a72ccc9ac7d02b 212 SUPERFAMILY SSF54862 9 170 2.62E-58 T 23-10-2018 TON_1017 f2b83241c658b01733a72ccc9ac7d02b 212 Gene3D G3DSA:3.30.70.20 5 206 3.2E-48 T 23-10-2018 TON_1717 4b8222fddf9507a592c3ee03e33d15e4 305 PIRSF PIRSF004976 1 301 1.7E-97 T 23-10-2018 IPR035107 tRNA thiolation protein, TtcA/Ctu1 type GO:0008033 Reactome: R-HSA-6782315 TON_1717 4b8222fddf9507a592c3ee03e33d15e4 305 TIGRFAM TIGR00269 TIGR00269: TIGR00269 family protein 192 291 2.5E-26 T 23-10-2018 IPR000541 Cytoplasmic tRNA 2-thiolation protein 1 GO:0000049|GO:0002098|GO:0034227 Reactome: R-HSA-6782315 TON_1717 4b8222fddf9507a592c3ee03e33d15e4 305 SUPERFAMILY SSF52402 26 245 9.26E-52 T 23-10-2018 TON_1717 4b8222fddf9507a592c3ee03e33d15e4 305 Gene3D G3DSA:3.40.50.620 3 304 1.3E-92 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TON_1717 4b8222fddf9507a592c3ee03e33d15e4 305 Pfam PF01171 PP-loop family 52 220 1.8E-12 T 23-10-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 TON_1656 ec647b14a4e534c3def43e1719e45ae0 190 Gene3D G3DSA:3.40.50.300 1 128 1.5E-26 T 23-10-2018 TON_1656 ec647b14a4e534c3def43e1719e45ae0 190 SUPERFAMILY SSF52540 6 105 7.91E-25 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_1656 ec647b14a4e534c3def43e1719e45ae0 190 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 25 88 2.0E-11 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TON_0267 f7a21460496266f6151cbc9ea7fe5731 161 PIRSF PIRSF019239 1 161 2.0E-40 T 23-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 TON_0267 f7a21460496266f6151cbc9ea7fe5731 161 Pfam PF01899 Na+/H+ ion antiporter subunit 9 159 1.4E-36 T 23-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 TON_0866 e7e6d7436c112020ff4d9a89ba6702b2 171 SUPERFAMILY SSF57802 137 170 2.36E-10 T 23-10-2018 TON_0866 e7e6d7436c112020ff4d9a89ba6702b2 171 Pfam PF02915 Rubrerythrin 10 124 1.1E-26 T 23-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 TON_0866 e7e6d7436c112020ff4d9a89ba6702b2 171 SUPERFAMILY SSF47240 5 133 4.38E-39 T 23-10-2018 IPR009078 Ferritin-like superfamily TON_0866 e7e6d7436c112020ff4d9a89ba6702b2 171 Gene3D G3DSA:1.20.1260.10 3 132 1.4E-47 T 23-10-2018 IPR012347 Ferritin-like TON_0866 e7e6d7436c112020ff4d9a89ba6702b2 171 Gene3D G3DSA:2.20.28.10 133 171 5.2E-17 T 23-10-2018 TON_0737 9fd3df2e7ab6ac3db587878d18382136 290 Pfam PF13588 Type I restriction enzyme R protein N terminus (HSDR_N) 25 119 1.2E-8 T 23-10-2018 IPR029464 Type I restriction enzyme R protein, N-terminal domain TON_1747 80b58d311bed42d65a423411ab3ef01e 659 Gene3D G3DSA:3.30.70.2750 149 224 1.8E-24 T 23-10-2018 TON_1747 80b58d311bed42d65a423411ab3ef01e 659 Gene3D G3DSA:1.20.1460.20 47 290 1.8E-24 T 23-10-2018 TON_1747 80b58d311bed42d65a423411ab3ef01e 659 Pfam PF01496 V-type ATPase 116kDa subunit family 547 647 2.0E-12 T 23-10-2018 IPR002490 V-type ATPase, V0 complex, 116kDa subunit family GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TON_1747 80b58d311bed42d65a423411ab3ef01e 659 Pfam PF01496 V-type ATPase 116kDa subunit family 142 448 9.4E-26 T 23-10-2018 IPR002490 V-type ATPase, V0 complex, 116kDa subunit family GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TON_1747 80b58d311bed42d65a423411ab3ef01e 659 Gene3D G3DSA:3.30.70.2170 7 310 1.8E-24 T 23-10-2018 TON_1112 157a0a0f70ae401af02700c58c2fbbe0 161 Gene3D G3DSA:2.30.30.60 105 154 1.9E-9 T 23-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily TON_1112 157a0a0f70ae401af02700c58c2fbbe0 161 Pfam PF00924 Mechanosensitive ion channel 48 155 2.7E-19 T 23-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 TON_1112 157a0a0f70ae401af02700c58c2fbbe0 161 SUPERFAMILY SSF50182 89 153 2.13E-13 T 23-10-2018 IPR010920 LSM domain superfamily TON_1112 157a0a0f70ae401af02700c58c2fbbe0 161 SUPERFAMILY SSF82861 4 87 7.72E-7 T 23-10-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 TON_0862 7427633fca844544f8ebad38c7b44d90 150 SUPERFAMILY SSF52833 1 149 4.99E-47 T 23-10-2018 IPR036249 Thioredoxin-like superfamily TON_0862 7427633fca844544f8ebad38c7b44d90 150 PIRSF PIRSF000239 1 150 5.7E-23 T 23-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 TON_0862 7427633fca844544f8ebad38c7b44d90 150 Pfam PF00578 AhpC/TSA family 4 129 8.7E-34 T 23-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 TON_0862 7427633fca844544f8ebad38c7b44d90 150 Gene3D G3DSA:3.40.30.10 1 150 4.0E-46 T 23-10-2018 TON_0865 ca9fafcdef35e37277f5ab75d276e7c1 361 SUPERFAMILY SSF51905 114 287 1.81E-26 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TON_0865 ca9fafcdef35e37277f5ab75d276e7c1 361 SUPERFAMILY SSF51905 2 172 1.09E-39 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TON_0865 ca9fafcdef35e37277f5ab75d276e7c1 361 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 279 6.3E-54 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TON_0865 ca9fafcdef35e37277f5ab75d276e7c1 361 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 94 112 1.1E-20 T 23-10-2018 TON_0865 ca9fafcdef35e37277f5ab75d276e7c1 361 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 240 262 1.1E-20 T 23-10-2018 TON_0865 ca9fafcdef35e37277f5ab75d276e7c1 361 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 137 155 1.1E-20 T 23-10-2018 TON_0865 ca9fafcdef35e37277f5ab75d276e7c1 361 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 3 22 1.1E-20 T 23-10-2018 TON_0865 ca9fafcdef35e37277f5ab75d276e7c1 361 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 133 157 1.2E-6 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TON_0865 ca9fafcdef35e37277f5ab75d276e7c1 361 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 250 268 1.2E-6 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TON_0865 ca9fafcdef35e37277f5ab75d276e7c1 361 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 2 24 1.2E-6 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TON_0865 ca9fafcdef35e37277f5ab75d276e7c1 361 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 95 103 1.2E-6 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TON_0865 ca9fafcdef35e37277f5ab75d276e7c1 361 Gene3D G3DSA:3.30.390.30 299 357 6.2E-24 T 23-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 TON_0865 ca9fafcdef35e37277f5ab75d276e7c1 361 Gene3D G3DSA:3.50.50.60 3 277 3.4E-99 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TON_0865 ca9fafcdef35e37277f5ab75d276e7c1 361 SUPERFAMILY SSF55424 291 351 1.76E-20 T 23-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 TON_0865 ca9fafcdef35e37277f5ab75d276e7c1 361 Gene3D G3DSA:3.50.50.60 106 223 3.4E-99 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TON_1310 1ba5f80ae16812638c8278c4a85a0051 335 Gene3D G3DSA:3.40.800.20 5 332 3.7E-82 T 23-10-2018 IPR037138 Histone deacetylase domain superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 TON_1310 1ba5f80ae16812638c8278c4a85a0051 335 Pfam PF00850 Histone deacetylase domain 21 289 2.9E-66 T 23-10-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 TON_1310 1ba5f80ae16812638c8278c4a85a0051 335 SUPERFAMILY SSF52768 6 334 7.67E-88 T 23-10-2018 IPR023696 Ureohydrolase domain superfamily TON_1310 1ba5f80ae16812638c8278c4a85a0051 335 PRINTS PR01270 Histone deacetylase superfamily signature 240 250 3.7E-11 T 23-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 TON_1310 1ba5f80ae16812638c8278c4a85a0051 335 PRINTS PR01270 Histone deacetylase superfamily signature 124 147 3.7E-11 T 23-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 TON_1310 1ba5f80ae16812638c8278c4a85a0051 335 PRINTS PR01270 Histone deacetylase superfamily signature 156 171 3.7E-11 T 23-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 TON_1721 1396e552c04c017bf1d1ab2f17994e96 205 Pfam PF01914 MarC family integral membrane protein 4 196 2.8E-30 T 23-10-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 TON_1660 c475906350608463b6a3be006c1b8125 458 Gene3D G3DSA:3.20.20.80 26 360 1.3E-105 T 23-10-2018 TON_1660 c475906350608463b6a3be006c1b8125 458 SMART SM00642 33 378 5.1E-24 T 23-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 TON_1660 c475906350608463b6a3be006c1b8125 458 SUPERFAMILY SSF51011 385 458 5.25E-38 T 23-10-2018 TON_1660 c475906350608463b6a3be006c1b8125 458 Gene3D G3DSA:2.60.40.1180 361 458 1.2E-50 T 23-10-2018 IPR013780 Glycosyl hydrolase, all-beta TON_1660 c475906350608463b6a3be006c1b8125 458 Pfam PF00128 Alpha amylase, catalytic domain 63 318 8.6E-12 T 23-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 TON_1660 c475906350608463b6a3be006c1b8125 458 Pfam PF09154 Domain of unknown function (DUF1939) 387 453 6.0E-22 T 23-10-2018 IPR015237 Alpha-amylase C-terminal, prokaryotic GO:0004553 TON_1660 c475906350608463b6a3be006c1b8125 458 SUPERFAMILY SSF51445 30 382 2.66E-68 T 23-10-2018 IPR017853 Glycoside hydrolase superfamily TON_1660 c475906350608463b6a3be006c1b8125 458 PIRSF PIRSF001021 3 458 1.3E-115 T 23-10-2018 IPR013776 Alpha-amylase, thermostable GO:0004553|GO:0005509|GO:0005975 KEGG: 00500+3.2.1.1 TON_0662 6943650e1b2280e1b40a638ad95bbe2a 160 SMART SM00344 4 105 2.3E-8 T 23-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 TON_0662 6943650e1b2280e1b40a638ad95bbe2a 160 Gene3D G3DSA:3.30.70.920 57 160 4.1E-33 T 23-10-2018 TON_0662 6943650e1b2280e1b40a638ad95bbe2a 160 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 31 50 6.6E-12 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TON_0662 6943650e1b2280e1b40a638ad95bbe2a 160 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 4 20 6.6E-12 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TON_0662 6943650e1b2280e1b40a638ad95bbe2a 160 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 20 31 6.6E-12 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TON_0662 6943650e1b2280e1b40a638ad95bbe2a 160 Gene3D G3DSA:1.10.10.10 1 56 1.6E-23 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TON_0662 6943650e1b2280e1b40a638ad95bbe2a 160 Pfam PF13412 Winged helix-turn-helix DNA-binding 4 50 2.6E-14 T 23-10-2018 TON_0662 6943650e1b2280e1b40a638ad95bbe2a 160 SUPERFAMILY SSF46785 3 59 1.61E-13 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TON_0907 e1213492eab3d9304ecad9e4dcabf631 330 Gene3D G3DSA:3.40.50.300 6 330 1.0E-87 T 23-10-2018 TON_0907 e1213492eab3d9304ecad9e4dcabf631 330 Pfam PF02374 Anion-transporting ATPase 12 326 4.6E-72 T 23-10-2018 IPR025723 Anion-transporting ATPase-like domain Reactome: R-HSA-381038 TON_0907 e1213492eab3d9304ecad9e4dcabf631 330 TIGRFAM TIGR00345 GET3_arsA_TRC40: transport-energizing ATPase, TRC40/GET3/ArsA family 15 323 7.6E-74 T 23-10-2018 IPR016300 Arsenical pump ATPase, ArsA/GET3 GO:0005524|GO:0016887 Reactome: R-HSA-381038 TON_0907 e1213492eab3d9304ecad9e4dcabf631 330 SUPERFAMILY SSF52540 12 321 1.09E-45 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_0384 eb9cad6d90b013b8089a1bb258c8a897 160 SUPERFAMILY SSF159902 2 156 3.14E-71 T 23-10-2018 TON_0384 eb9cad6d90b013b8089a1bb258c8a897 160 Pfam PF09638 Ph1570 protein 1 156 1.5E-79 T 23-10-2018 IPR023110 PH1570-like domain TON_0384 eb9cad6d90b013b8089a1bb258c8a897 160 Gene3D G3DSA:3.40.1600.10 1 157 6.6E-71 T 23-10-2018 IPR036807 PH1570-like superfamily TON_1675 37fd612be1f0855926147955ef5b6be2 619 SMART SM00382 352 517 0.006 T 23-10-2018 IPR003593 AAA+ ATPase domain TON_1675 37fd612be1f0855926147955ef5b6be2 619 Gene3D G3DSA:3.40.50.300 320 607 3.2E-102 T 23-10-2018 TON_1675 37fd612be1f0855926147955ef5b6be2 619 SUPERFAMILY SSF52540 205 519 1.94E-56 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_1675 37fd612be1f0855926147955ef5b6be2 619 Gene3D G3DSA:3.30.450.380 101 319 9.5E-66 T 23-10-2018 TON_1675 37fd612be1f0855926147955ef5b6be2 619 Pfam PF00437 Type II/IV secretion system protein 225 484 5.4E-65 T 23-10-2018 IPR001482 Type II/IV secretion system protein TON_1397 b83a6ab7f07926977ad140a690dda964 526 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 30 39 - T 23-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 TON_1397 b83a6ab7f07926977ad140a690dda964 526 Gene3D G3DSA:2.30.30.300 170 213 1.0E-109 T 23-10-2018 IPR023386 Lysine-tRNA ligase, insertion domain superfamily GO:0004824 KEGG: 00970+6.1.1.6 TON_1397 b83a6ab7f07926977ad140a690dda964 526 SUPERFAMILY SSF48163 323 523 4.05E-49 T 23-10-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 TON_1397 b83a6ab7f07926977ad140a690dda964 526 Gene3D G3DSA:1.10.10.350 434 526 9.0E-25 T 23-10-2018 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 TON_1397 b83a6ab7f07926977ad140a690dda964 526 Gene3D G3DSA:1.10.10.770 319 433 5.1E-39 T 23-10-2018 TON_1397 b83a6ab7f07926977ad140a690dda964 526 TIGRFAM TIGR00467 lysS_arch: lysine--tRNA ligase 2 523 5.2E-159 T 23-10-2018 IPR002904 Lysine-tRNA ligase GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 TON_1397 b83a6ab7f07926977ad140a690dda964 526 SUPERFAMILY SSF52374 3 319 8.45E-69 T 23-10-2018 TON_1397 b83a6ab7f07926977ad140a690dda964 526 Gene3D G3DSA:1.10.10.860 271 318 2.1E-23 T 23-10-2018 TON_1397 b83a6ab7f07926977ad140a690dda964 526 Gene3D G3DSA:3.40.50.620 4 270 1.0E-109 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TON_1397 b83a6ab7f07926977ad140a690dda964 526 Pfam PF01921 tRNA synthetases class I (K) 3 362 5.0E-138 T 23-10-2018 IPR002904 Lysine-tRNA ligase GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 TON_1397 b83a6ab7f07926977ad140a690dda964 526 Hamap MF_00177 Lysine--tRNA ligase [lysS]. 2 526 37.936 T 23-10-2018 IPR002904 Lysine-tRNA ligase GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 TON_1691 60e0669d0859d2a33936c6044761aa11 644 Pfam PF04312 Protein of unknown function (DUF460) 189 329 3.1E-49 T 23-10-2018 IPR007408 Protein of unknown function DUF460 TON_1788 03b0bec001f8fc9427e4c6fe7c735e0d 281 SUPERFAMILY SSF56281 13 261 1.31E-34 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TON_1788 03b0bec001f8fc9427e4c6fe7c735e0d 281 Gene3D G3DSA:3.60.15.10 9 263 5.2E-28 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TON_1788 03b0bec001f8fc9427e4c6fe7c735e0d 281 Pfam PF12706 Beta-lactamase superfamily domain 42 230 1.4E-25 T 23-10-2018 IPR001279 Metallo-beta-lactamase TON_0585 d34d143628ce39833c30c345d3e5b40e 170 Gene3D G3DSA:3.40.920.10 1 170 2.4E-54 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 TON_0585 d34d143628ce39833c30c345d3e5b40e 170 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 9 166 2.7E-38 T 23-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 TON_0585 d34d143628ce39833c30c345d3e5b40e 170 SUPERFAMILY SSF53323 2 168 9.02E-43 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 TON_0278 6a62f3d8bfa45fdcae43f144e1088180 659 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 297 309 8.4E-14 T 23-10-2018 TON_0278 6a62f3d8bfa45fdcae43f144e1088180 659 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 415 434 8.4E-14 T 23-10-2018 TON_0278 6a62f3d8bfa45fdcae43f144e1088180 659 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 65 90 8.4E-14 T 23-10-2018 TON_0278 6a62f3d8bfa45fdcae43f144e1088180 659 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 206 227 8.4E-14 T 23-10-2018 TON_0278 6a62f3d8bfa45fdcae43f144e1088180 659 Pfam PF00361 Proton-conducting membrane transporter 120 417 4.7E-52 T 23-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_0278 6a62f3d8bfa45fdcae43f144e1088180 659 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 59 97 9.2E-7 T 23-10-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_0156 680bf5dfb39569aa23a18644eb8a85ab 527 ProSitePatterns PS00610 Sodium:neurotransmitter symporter family signature 1. 28 42 - T 23-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 TON_0156 680bf5dfb39569aa23a18644eb8a85ab 527 SUPERFAMILY SSF161070 4 480 4.45E-109 T 23-10-2018 IPR037272 Sodium:neurotransmitter symporter superfamily GO:0005328 TON_0156 680bf5dfb39569aa23a18644eb8a85ab 527 Pfam PF00209 Sodium:neurotransmitter symporter family 4 132 6.7E-24 T 23-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 TON_0156 680bf5dfb39569aa23a18644eb8a85ab 527 Pfam PF00209 Sodium:neurotransmitter symporter family 164 463 3.8E-31 T 23-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 TON_0156 680bf5dfb39569aa23a18644eb8a85ab 527 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 397 417 1.8E-18 T 23-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 TON_0156 680bf5dfb39569aa23a18644eb8a85ab 527 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 320 339 1.8E-18 T 23-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 TON_0156 680bf5dfb39569aa23a18644eb8a85ab 527 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 12 33 1.8E-18 T 23-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 TON_0156 680bf5dfb39569aa23a18644eb8a85ab 527 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 41 60 1.8E-18 T 23-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 TON_1864 336f3aa28c1184f4cc99f52eed5cc8a0 263 Gene3D G3DSA:3.10.450.620 21 136 2.3E-5 T 23-10-2018 TON_1864 336f3aa28c1184f4cc99f52eed5cc8a0 263 Pfam PF08843 Nucleotidyl transferase AbiEii toxin, Type IV TA system 35 250 1.6E-27 T 23-10-2018 IPR014942 Nucleotidyl transferase AbiEii toxin, Type IV TA system TON_0145 5bf33ae2bdb4dacaaf49770858d7e45d 151 Gene3D G3DSA:3.30.1440.10 2 149 1.1E-43 T 23-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0145 5bf33ae2bdb4dacaaf49770858d7e45d 151 Pfam PF01877 RNA binding 9 131 1.5E-37 T 23-10-2018 IPR002739 Uncharacterised protein family UPF0201 TON_0145 5bf33ae2bdb4dacaaf49770858d7e45d 151 SUPERFAMILY SSF55282 7 149 1.53E-41 T 23-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0540 9bd9f63d12270317f4f62371b3d629fd 163 Pfam PF13247 4Fe-4S dicluster domain 41 130 3.7E-25 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TON_0540 9bd9f63d12270317f4f62371b3d629fd 163 PRINTS PR00354 7Fe ferredoxin signature 45 55 6.6E-5 T 23-10-2018 IPR000813 7Fe ferredoxin GO:0009055 TON_0540 9bd9f63d12270317f4f62371b3d629fd 163 PRINTS PR00354 7Fe ferredoxin signature 55 65 6.6E-5 T 23-10-2018 IPR000813 7Fe ferredoxin GO:0009055 TON_0540 9bd9f63d12270317f4f62371b3d629fd 163 PRINTS PR00354 7Fe ferredoxin signature 72 89 6.6E-5 T 23-10-2018 IPR000813 7Fe ferredoxin GO:0009055 TON_0540 9bd9f63d12270317f4f62371b3d629fd 163 Gene3D G3DSA:3.30.70.20 30 163 1.4E-38 T 23-10-2018 TON_0540 9bd9f63d12270317f4f62371b3d629fd 163 SUPERFAMILY SSF54862 3 146 2.83E-50 T 23-10-2018 TON_0540 9bd9f63d12270317f4f62371b3d629fd 163 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 77 88 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TON_0326 75f0bceb3b647c3eb56b7fea2ab23db9 263 Gene3D G3DSA:3.30.70.1890 1 122 8.5E-39 T 23-10-2018 TON_0326 75f0bceb3b647c3eb56b7fea2ab23db9 263 Pfam PF01881 CRISPR associated protein Cas6 95 239 4.8E-34 T 23-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 TON_0326 75f0bceb3b647c3eb56b7fea2ab23db9 263 TIGRFAM TIGR01877 cas_cas6: CRISPR-associated endoribonuclease Cas6 43 238 2.0E-47 T 23-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 TON_0326 75f0bceb3b647c3eb56b7fea2ab23db9 263 Gene3D G3DSA:3.30.70.1900 123 241 2.3E-38 T 23-10-2018 TON_0326 75f0bceb3b647c3eb56b7fea2ab23db9 263 PIRSF PIRSF005054 1 243 5.0E-68 T 23-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 TON_1417 f0bedbf456d5e3b380ceb51648b85bcf 171 TIGRFAM TIGR00324 endA: tRNA-intron lyase 7 169 8.0E-42 T 23-10-2018 IPR006676 tRNA-splicing endonuclease GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803|Reactome: R-HSA-6784531 TON_1417 f0bedbf456d5e3b380ceb51648b85bcf 171 PIRSF PIRSF005285 8 171 1.3E-65 T 23-10-2018 IPR016442 tRNA-splicing endonuclease, archaeal short subfamily MetaCyc: PWY-6689|MetaCyc: PWY-7803 TON_1417 f0bedbf456d5e3b380ceb51648b85bcf 171 Pfam PF02778 tRNA intron endonuclease, N-terminal domain 6 70 1.5E-21 T 23-10-2018 IPR006678 tRNA intron endonuclease, N-terminal GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803|Reactome: R-HSA-6784531 TON_1417 f0bedbf456d5e3b380ceb51648b85bcf 171 Pfam PF01974 tRNA intron endonuclease, catalytic C-terminal domain 80 163 2.5E-30 T 23-10-2018 IPR006677 tRNA intron endonuclease, catalytic domain-like GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803|Reactome: R-HSA-6784531 TON_1417 f0bedbf456d5e3b380ceb51648b85bcf 171 Gene3D G3DSA:3.40.1170.20 5 73 5.1E-18 T 23-10-2018 TON_1417 f0bedbf456d5e3b380ceb51648b85bcf 171 SUPERFAMILY SSF55267 5 76 4.12E-19 T 23-10-2018 IPR036740 tRNA intron endonuclease, N-terminal domain superfamily GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803 TON_1417 f0bedbf456d5e3b380ceb51648b85bcf 171 SUPERFAMILY SSF53032 79 169 1.02E-29 T 23-10-2018 IPR036167 tRNA intron endonuclease, catalytic domain-like superfamily GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803|Reactome: R-HSA-6784531 TON_1417 f0bedbf456d5e3b380ceb51648b85bcf 171 Gene3D G3DSA:3.40.1350.10 79 171 1.5E-32 T 23-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 TON_1417 f0bedbf456d5e3b380ceb51648b85bcf 171 Hamap MF_01833 tRNA-splicing endonuclease [endA]. 5 171 34.477 T 23-10-2018 IPR016442 tRNA-splicing endonuclease, archaeal short subfamily MetaCyc: PWY-6689|MetaCyc: PWY-7803 TON_0884 143e5b79dded65d1169c526f4c219097 252 SUPERFAMILY SSF51366 1 249 3.92E-86 T 23-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 TON_0884 143e5b79dded65d1169c526f4c219097 252 Gene3D G3DSA:3.20.20.70 1 252 9.2E-110 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TON_0884 143e5b79dded65d1169c526f4c219097 252 Pfam PF00977 Histidine biosynthesis protein 5 233 2.5E-89 T 23-10-2018 IPR006062 Histidine biosynthesis GO:0000105 TON_0884 143e5b79dded65d1169c526f4c219097 252 Hamap MF_01013 Imidazole glycerol phosphate synthase subunit HisF [hisF]. 1 249 48.26 T 23-10-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 TON_0884 143e5b79dded65d1169c526f4c219097 252 TIGRFAM TIGR00735 hisF: imidazoleglycerol phosphate synthase, cyclase subunit 1 249 2.8E-110 T 23-10-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 TON_1862 5619a925483fae1438eab7ac697f969e 296 SUPERFAMILY SSF53448 4 209 1.95E-39 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TON_1862 5619a925483fae1438eab7ac697f969e 296 Pfam PF00535 Glycosyl transferase family 2 7 165 3.5E-27 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TON_1862 5619a925483fae1438eab7ac697f969e 296 Gene3D G3DSA:3.90.550.10 2 229 2.4E-52 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TON_1894 204c108dcecbcedf5c719736a87efe5a 188 Pfam PF00117 Glutamine amidotransferase class-I 4 181 2.0E-45 T 23-10-2018 IPR017926 Glutamine amidotransferase TON_1894 204c108dcecbcedf5c719736a87efe5a 188 SUPERFAMILY SSF52317 1 186 2.81E-54 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like TON_1894 204c108dcecbcedf5c719736a87efe5a 188 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 43 57 7.6E-6 T 23-10-2018 TON_1894 204c108dcecbcedf5c719736a87efe5a 188 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 73 89 7.6E-6 T 23-10-2018 TON_1894 204c108dcecbcedf5c719736a87efe5a 188 PRINTS PR00096 Glutamine amidotransferase superfamily signature 46 55 1.1E-9 T 23-10-2018 TON_1894 204c108dcecbcedf5c719736a87efe5a 188 PRINTS PR00096 Glutamine amidotransferase superfamily signature 73 84 1.1E-9 T 23-10-2018 TON_1894 204c108dcecbcedf5c719736a87efe5a 188 PRINTS PR00096 Glutamine amidotransferase superfamily signature 161 174 1.1E-9 T 23-10-2018 TON_1894 204c108dcecbcedf5c719736a87efe5a 188 PRINTS PR00097 Anthranilate synthase component II signature 2 16 1.9E-11 T 23-10-2018 TON_1894 204c108dcecbcedf5c719736a87efe5a 188 PRINTS PR00097 Anthranilate synthase component II signature 46 55 1.9E-11 T 23-10-2018 TON_1894 204c108dcecbcedf5c719736a87efe5a 188 PRINTS PR00097 Anthranilate synthase component II signature 73 84 1.9E-11 T 23-10-2018 TON_1894 204c108dcecbcedf5c719736a87efe5a 188 PRINTS PR00097 Anthranilate synthase component II signature 161 174 1.9E-11 T 23-10-2018 TON_1894 204c108dcecbcedf5c719736a87efe5a 188 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 2 186 8.3E-82 T 23-10-2018 IPR004739 GMP synthase, glutamine amidotransferase GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 TON_1894 204c108dcecbcedf5c719736a87efe5a 188 Gene3D G3DSA:3.40.50.880 1 187 1.0E-60 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like TON_1894 204c108dcecbcedf5c719736a87efe5a 188 Hamap MF_01510 GMP synthase [glutamine-hydrolyzing] subunit A [guaAA]. 1 187 45.231 T 23-10-2018 IPR023686 GMP synthase (glutamine-hydrolyzing) subunit A GO:0003922 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 TON_0610 b7f537ba4997450cc502e02a66548d77 361 Gene3D G3DSA:3.40.140.10 1 146 1.6E-50 T 23-10-2018 TON_0610 b7f537ba4997450cc502e02a66548d77 361 SUPERFAMILY SSF53597 152 351 7.4E-42 T 23-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 TON_0610 b7f537ba4997450cc502e02a66548d77 361 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 52 93 - T 23-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 TON_0610 b7f537ba4997450cc502e02a66548d77 361 Gene3D G3DSA:3.40.430.10 147 356 3.0E-50 T 23-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 TON_0610 b7f537ba4997450cc502e02a66548d77 361 SUPERFAMILY SSF53927 5 149 1.05E-47 T 23-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 TON_0610 b7f537ba4997450cc502e02a66548d77 361 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 2 105 1.1E-23 T 23-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain TON_0610 b7f537ba4997450cc502e02a66548d77 361 Pfam PF01872 RibD C-terminal domain 152 347 1.9E-29 T 23-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 TON_0610 b7f537ba4997450cc502e02a66548d77 361 TIGRFAM TIGR00326 eubact_ribD: riboflavin biosynthesis protein RibD 9 347 1.1E-98 T 23-10-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-7991 TON_0610 b7f537ba4997450cc502e02a66548d77 361 PIRSF PIRSF006769 1 354 2.2E-110 T 23-10-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-7991 TON_0249 1b9f0c2365b060153f1ff7aafaef6d68 59 Pfam PF07650 KH domain 7 56 1.6E-5 T 23-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0249 1b9f0c2365b060153f1ff7aafaef6d68 59 Gene3D G3DSA:3.30.300.20 5 58 4.3E-9 T 23-10-2018 IPR015946 K homology domain-like, alpha/beta TON_0249 1b9f0c2365b060153f1ff7aafaef6d68 59 SUPERFAMILY SSF54814 13 58 1.22E-7 T 23-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 TON_1755 102abdec5460db484ee48bea2f85a4bf 255 Pfam PF00753 Metallo-beta-lactamase superfamily 37 228 2.2E-18 T 23-10-2018 IPR001279 Metallo-beta-lactamase TON_1755 102abdec5460db484ee48bea2f85a4bf 255 SMART SM00849 39 228 4.9E-21 T 23-10-2018 IPR001279 Metallo-beta-lactamase TON_1755 102abdec5460db484ee48bea2f85a4bf 255 Gene3D G3DSA:3.60.15.10 3 247 9.3E-44 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TON_1755 102abdec5460db484ee48bea2f85a4bf 255 SUPERFAMILY SSF56281 34 244 4.72E-32 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TON_0676 c33e070ba64e90e7299793bed27c6cf6 193 SUPERFAMILY SSF47240 24 174 2.55E-23 T 23-10-2018 IPR009078 Ferritin-like superfamily TON_0676 c33e070ba64e90e7299793bed27c6cf6 193 Gene3D G3DSA:1.20.1260.10 22 172 2.1E-29 T 23-10-2018 IPR012347 Ferritin-like TON_0676 c33e070ba64e90e7299793bed27c6cf6 193 Pfam PF02915 Rubrerythrin 32 168 3.0E-21 T 23-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 TON_1650 88e520040965ae3d9fe8cb838d33e306 242 Gene3D G3DSA:3.40.50.10900 1 242 4.1E-73 T 23-10-2018 IPR038389 Proteasome assembly chaperone 2 superfamily TON_1650 88e520040965ae3d9fe8cb838d33e306 242 Pfam PF09754 PAC2 family 19 222 1.4E-47 T 23-10-2018 IPR019151 Proteasome assembly chaperone 2 TON_1650 88e520040965ae3d9fe8cb838d33e306 242 SUPERFAMILY SSF159659 11 240 1.01E-49 T 23-10-2018 TON_1650 88e520040965ae3d9fe8cb838d33e306 242 TIGRFAM TIGR00161 TIGR00161: TIGR00161 family protein 5 235 2.0E-66 T 23-10-2018 IPR004425 Conserved hypothetical protein CHP00061 TON_0076 f85780ff99dfc70716992a7aa8dca752 141 Pfam PF00238 Ribosomal protein L14p/L23e 24 140 9.9E-35 T 23-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 TON_0076 f85780ff99dfc70716992a7aa8dca752 141 SMART SM01374 20 141 1.2E-56 T 23-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 TON_0076 f85780ff99dfc70716992a7aa8dca752 141 TIGRFAM TIGR03673 uL14_arch: 50S ribosomal protein uL14 15 140 1.4E-60 T 23-10-2018 IPR019971 Ribosomal protein L14P, archaeal TON_0076 f85780ff99dfc70716992a7aa8dca752 141 Gene3D G3DSA:2.40.150.20 1 140 3.8E-49 T 23-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 TON_0076 f85780ff99dfc70716992a7aa8dca752 141 SUPERFAMILY SSF50193 16 141 6.02E-44 T 23-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 TON_0076 f85780ff99dfc70716992a7aa8dca752 141 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 20 141 19.514 T 23-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 TON_1860 d30c3e2eca036e1ba9d3823dc9f43087 147 SUPERFAMILY SSF53756 9 144 1.47E-13 T 23-10-2018 TON_1860 d30c3e2eca036e1ba9d3823dc9f43087 147 Pfam PF08660 Oligosaccharide biosynthesis protein Alg14 like 52 145 3.4E-17 T 23-10-2018 IPR013969 Oligosaccharide biosynthesis protein Alg14-like GO:0006488 Reactome: R-HSA-446193|Reactome: R-HSA-5633231 TON_1860 d30c3e2eca036e1ba9d3823dc9f43087 147 Gene3D G3DSA:3.40.50.2000 2 141 2.8E-12 T 23-10-2018 TON_0654 949c54c36fd2c088f795f88ad251eb3f 264 Pfam PF06508 Queuosine biosynthesis protein QueC 23 82 4.4E-8 T 23-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 TON_0654 949c54c36fd2c088f795f88ad251eb3f 264 Gene3D G3DSA:3.40.50.620 1 255 3.8E-29 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TON_0654 949c54c36fd2c088f795f88ad251eb3f 264 SUPERFAMILY SSF52402 21 212 1.1E-32 T 23-10-2018 TON_0654 949c54c36fd2c088f795f88ad251eb3f 264 PIRSF PIRSF036670 1 262 2.2E-123 T 23-10-2018 IPR012122 ATPase, PP-loop, MJ1016-related TON_0231 cf67053b3bffaddd9bb9159ee232b95b 399 Gene3D G3DSA:3.40.640.10 53 294 1.7E-144 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TON_0231 cf67053b3bffaddd9bb9159ee232b95b 399 PIRSF PIRSF000517 3 399 2.0E-80 T 23-10-2018 IPR005958 Tyrosine/nicotianamine aminotransferase GO:0006520|GO:0008483|GO:0030170 Reactome: R-HSA-71182 TON_0231 cf67053b3bffaddd9bb9159ee232b95b 399 SUPERFAMILY SSF53383 12 394 3.86E-107 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TON_0231 cf67053b3bffaddd9bb9159ee232b95b 399 Gene3D G3DSA:3.90.1150.10 24 390 1.7E-144 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TON_0231 cf67053b3bffaddd9bb9159ee232b95b 399 Pfam PF00155 Aminotransferase class I and II 31 383 2.2E-61 T 23-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 TON_1381 aa68b2b0164106b2bc67f70459022dea 191 Gene3D G3DSA:3.40.50.1390 1 132 2.4E-21 T 23-10-2018 TON_1381 aa68b2b0164106b2bc67f70459022dea 191 Pfam PF00239 Resolvase, N terminal domain 3 125 6.8E-21 T 23-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 TON_1381 aa68b2b0164106b2bc67f70459022dea 191 SMART SM00857 2 126 7.9E-8 T 23-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 TON_1381 aa68b2b0164106b2bc67f70459022dea 191 SUPERFAMILY SSF53041 2 125 2.09E-19 T 23-10-2018 IPR036162 Resolvase-like, N-terminal catalytic domain superfamily GO:0000150|GO:0003677|GO:0006310 TON_0419 a4189b6d8edf07d1c1283a1f44d49b28 311 PIRSF PIRSF005303 1 308 7.7E-90 T 23-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 TON_0419 a4189b6d8edf07d1c1283a1f44d49b28 311 Hamap MF_02128 Thiamine-monophosphate kinase [thiL]. 3 308 26.787 T 23-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 TON_0419 a4189b6d8edf07d1c1283a1f44d49b28 311 SUPERFAMILY SSF56042 136 294 4.78E-40 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily TON_0419 a4189b6d8edf07d1c1283a1f44d49b28 311 SUPERFAMILY SSF55326 9 132 2.99E-29 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily TON_0419 a4189b6d8edf07d1c1283a1f44d49b28 311 Pfam PF00586 AIR synthase related protein, N-terminal domain 23 132 6.2E-17 T 23-10-2018 IPR016188 PurM-like, N-terminal domain TON_0419 a4189b6d8edf07d1c1283a1f44d49b28 311 Pfam PF02769 AIR synthase related protein, C-terminal domain 143 290 9.3E-9 T 23-10-2018 IPR010918 PurM-like, C-terminal domain TON_0419 a4189b6d8edf07d1c1283a1f44d49b28 311 Gene3D G3DSA:3.90.650.10 138 308 1.6E-45 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily TON_0419 a4189b6d8edf07d1c1283a1f44d49b28 311 TIGRFAM TIGR01379 thiL: thiamine-phosphate kinase 2 308 3.5E-86 T 23-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 TON_0419 a4189b6d8edf07d1c1283a1f44d49b28 311 Gene3D G3DSA:3.30.1330.10 1 136 2.1E-32 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily TON_1333 5af3d218d6d5d8dcc414822870afa824 201 Pfam PF01899 Na+/H+ ion antiporter subunit 42 199 5.6E-40 T 23-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 TON_1333 5af3d218d6d5d8dcc414822870afa824 201 PIRSF PIRSF019239 29 201 3.9E-49 T 23-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 TON_1105 eed2234ff82ceaf447120954e6001793 199 SUPERFAMILY SSF52402 1 149 6.4E-23 T 23-10-2018 TON_1105 eed2234ff82ceaf447120954e6001793 199 Gene3D G3DSA:3.40.50.620 1 199 2.5E-64 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TON_1105 eed2234ff82ceaf447120954e6001793 199 Pfam PF00733 Asparagine synthase 8 66 1.4E-4 T 23-10-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 TON_1217 757bbabb524c0e59092df80f0df1cfd9 185 Pfam PF01926 50S ribosome-binding GTPase 3 136 1.7E-22 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 TON_1217 757bbabb524c0e59092df80f0df1cfd9 185 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 2 176 2.6E-20 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 TON_1217 757bbabb524c0e59092df80f0df1cfd9 185 Gene3D G3DSA:3.40.50.300 1 182 6.7E-36 T 23-10-2018 TON_1217 757bbabb524c0e59092df80f0df1cfd9 185 SUPERFAMILY SSF52540 2 182 2.88E-35 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_1217 757bbabb524c0e59092df80f0df1cfd9 185 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 4 24 4.3E-6 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 TON_1217 757bbabb524c0e59092df80f0df1cfd9 185 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 65 80 4.3E-6 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 TON_1316 bf1f484e951e0ba251fa447c22287f95 48 SUPERFAMILY SSF57667 13 43 1.57E-5 T 23-10-2018 IPR036236 Zinc finger C2H2 superfamily TON_1316 bf1f484e951e0ba251fa447c22287f95 48 Pfam PF00096 Zinc finger, C2H2 type 18 41 2.2E-6 T 23-10-2018 IPR013087 Zinc finger C2H2-type GO:0003676 TON_1316 bf1f484e951e0ba251fa447c22287f95 48 ProSitePatterns PS00028 Zinc finger C2H2 type domain signature. 20 41 - T 23-10-2018 IPR013087 Zinc finger C2H2-type GO:0003676 TON_1529 0ae3d809c6764717d3bcf7da916a4d23 175 Pfam PF02572 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP 8 175 7.3E-63 T 23-10-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17 TON_1529 0ae3d809c6764717d3bcf7da916a4d23 175 PIRSF PIRSF015617 1 175 3.2E-64 T 23-10-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17 TON_1529 0ae3d809c6764717d3bcf7da916a4d23 175 SUPERFAMILY SSF52540 4 175 1.01E-58 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_1529 0ae3d809c6764717d3bcf7da916a4d23 175 TIGRFAM TIGR00708 cobA: cob(I)yrinic acid a,c-diamide adenosyltransferase 3 175 1.0E-71 T 23-10-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17 TON_1529 0ae3d809c6764717d3bcf7da916a4d23 175 Gene3D G3DSA:3.40.50.300 2 175 4.7E-66 T 23-10-2018 TON_1797 7777cc40ce2312cf160d2fdf6bef8492 340 Gene3D G3DSA:1.10.10.10 2 101 5.7E-30 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TON_1797 7777cc40ce2312cf160d2fdf6bef8492 340 SUPERFAMILY SSF46785 4 94 8.69E-10 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TON_1797 7777cc40ce2312cf160d2fdf6bef8492 340 Pfam PF11495 Archaeal transcriptional regulator TrmB 112 338 7.8E-52 T 23-10-2018 IPR021586 Transcription regulator TrmB, C-terminal TON_1797 7777cc40ce2312cf160d2fdf6bef8492 340 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 10 77 1.2E-24 T 23-10-2018 IPR002831 Transcription regulator TrmB, N-terminal TON_1797 7777cc40ce2312cf160d2fdf6bef8492 340 SUPERFAMILY SSF159071 255 339 2.09E-20 T 23-10-2018 TON_0725 edea9fd1f4cc02f66fb638c6fdc7a11d 891 Gene3D G3DSA:3.40.50.300 253 409 8.9E-25 T 23-10-2018 TON_0725 edea9fd1f4cc02f66fb638c6fdc7a11d 891 Pfam PF09369 Domain of unknown function (DUF1998) 782 864 2.0E-15 T 23-10-2018 IPR018973 DEAD/DEAH-box helicase, putative TON_0725 edea9fd1f4cc02f66fb638c6fdc7a11d 891 SMART SM00487 44 253 3.1E-28 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TON_0725 edea9fd1f4cc02f66fb638c6fdc7a11d 891 Pfam PF00270 DEAD/DEAH box helicase 51 224 1.3E-21 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 TON_0725 edea9fd1f4cc02f66fb638c6fdc7a11d 891 SMART SM00490 292 376 1.8E-20 T 23-10-2018 IPR001650 Helicase, C-terminal TON_0725 edea9fd1f4cc02f66fb638c6fdc7a11d 891 Gene3D G3DSA:3.40.50.300 28 241 2.0E-40 T 23-10-2018 TON_0725 edea9fd1f4cc02f66fb638c6fdc7a11d 891 SUPERFAMILY SSF52540 58 378 1.84E-49 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_0725 edea9fd1f4cc02f66fb638c6fdc7a11d 891 Pfam PF00271 Helicase conserved C-terminal domain 273 375 2.2E-19 T 23-10-2018 IPR001650 Helicase, C-terminal TON_0782 21e49aa3c7f4c91f07fafd060960f174 203 Pfam PF04013 Putative SAM-dependent RNA methyltransferase 1 197 4.4E-47 T 23-10-2018 IPR007158 tRNA (pseudouridine(54)-N(1))-methyltransferase, TrmY GO:0008175 TON_0782 21e49aa3c7f4c91f07fafd060960f174 203 SUPERFAMILY SSF75217 1 198 2.97E-65 T 23-10-2018 IPR029028 Alpha/beta knot methyltransferases TON_0782 21e49aa3c7f4c91f07fafd060960f174 203 Gene3D G3DSA:3.40.1280.10 1 200 4.2E-69 T 23-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal TON_0782 21e49aa3c7f4c91f07fafd060960f174 203 Hamap MF_00587 tRNA (pseudouridine(54)-N(1))-methyltransferase [trmY]. 1 200 35.712 T 23-10-2018 IPR007158 tRNA (pseudouridine(54)-N(1))-methyltransferase, TrmY GO:0008175 TON_1927 a9711fe08a09e934c4fcdef51e925242 129 Pfam PF08281 Sigma-70, region 4 11 46 1.9E-6 T 23-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TON_1927 a9711fe08a09e934c4fcdef51e925242 129 Gene3D G3DSA:1.10.10.10 1 52 6.0E-7 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TON_1927 a9711fe08a09e934c4fcdef51e925242 129 SUPERFAMILY SSF88659 10 49 2.62E-7 T 23-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like TON_0827 0631dd58691b86213b03171e32813aff 189 Gene3D G3DSA:1.20.58.1030 1 113 3.7E-46 T 23-10-2018 TON_0827 0631dd58691b86213b03171e32813aff 189 Gene3D G3DSA:3.40.5.50 135 188 3.5E-25 T 23-10-2018 TON_0820 82bb06400a7d162c79eca5fe13eb2d55 394 Pfam PF03222 Tryptophan/tyrosine permease family 65 393 2.0E-26 T 23-10-2018 IPR018227 Amino acid/polyamine transporter 2 GO:0003333 TON_1499 fc455cebbe7b79b5b81f06f2da1fcd90 557 SUPERFAMILY SSF48239 360 555 6.91E-10 T 23-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid TON_1499 fc455cebbe7b79b5b81f06f2da1fcd90 557 SUPERFAMILY SSF48239 27 345 9.6E-9 T 23-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid TON_1142 798334d1c394651779feab0b1da441c8 256 Gene3D G3DSA:3.40.50.720 1 155 1.2E-22 T 23-10-2018 TON_1142 798334d1c394651779feab0b1da441c8 256 Pfam PF02153 Prephenate dehydrogenase 44 174 6.7E-12 T 23-10-2018 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 TON_1142 798334d1c394651779feab0b1da441c8 256 SUPERFAMILY SSF51735 1 147 2.99E-22 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TON_1209 29db5becd18170b51b2bcf90e075e143 134 Gene3D G3DSA:2.20.25.200 65 120 3.2E-26 T 23-10-2018 TON_1209 29db5becd18170b51b2bcf90e075e143 134 Hamap MF_00757 Ribonuclease P protein component 4 [rnp4]. 11 110 25.884 T 23-10-2018 IPR016432 Ribonuclease P, protein component 4 GO:0001682|GO:0004526 TON_1209 29db5becd18170b51b2bcf90e075e143 134 PIRSF PIRSF004878 1 117 2.8E-42 T 23-10-2018 IPR016432 Ribonuclease P, protein component 4 GO:0001682|GO:0004526 TON_1209 29db5becd18170b51b2bcf90e075e143 134 Pfam PF04032 RNAse P Rpr2/Rpp21/SNM1 subunit domain 22 101 4.9E-18 T 23-10-2018 IPR007175 RNAse P, Rpr2/Rpp21 subunit Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 TON_1209 29db5becd18170b51b2bcf90e075e143 134 Gene3D G3DSA:1.20.5.420 6 64 5.0E-22 T 23-10-2018 TON_1554 39146d35024881a58c09a58f5a83ac6f 118 Gene3D G3DSA:2.60.120.10 4 116 1.3E-32 T 23-10-2018 IPR014710 RmlC-like jelly roll fold TON_1554 39146d35024881a58c09a58f5a83ac6f 118 Pfam PF07883 Cupin domain 38 103 2.6E-15 T 23-10-2018 IPR013096 Cupin 2, conserved barrel TON_1554 39146d35024881a58c09a58f5a83ac6f 118 SUPERFAMILY SSF51182 7 105 4.89E-28 T 23-10-2018 IPR011051 RmlC-like cupin domain superfamily TON_1027 98dfaa844b997b8ecd7a15290d354d2e 84 Pfam PF13244 Domain of unknown function (DUF4040) 16 79 6.5E-11 T 23-10-2018 IPR025383 Domain of unknown function DUF4040 TON_1303 2c061871dc2a8d5dbbac36fce46ca51f 134 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 49 111 4.2E-22 T 23-10-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal TON_1303 2c061871dc2a8d5dbbac36fce46ca51f 134 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 17 47 4.6E-10 T 23-10-2018 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal TON_1303 2c061871dc2a8d5dbbac36fce46ca51f 134 SUPERFAMILY SSF50249 7 116 1.88E-33 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold TON_1303 2c061871dc2a8d5dbbac36fce46ca51f 134 Gene3D G3DSA:1.10.12.20 4 51 7.8E-6 T 23-10-2018 TON_1821 1b1ae3cde18a5fbabeb684baf8990514 374 SUPERFAMILY SSF53756 1 372 1.88E-69 T 23-10-2018 TON_1821 1b1ae3cde18a5fbabeb684baf8990514 374 Pfam PF13439 Glycosyltransferase Family 4 16 181 2.2E-18 T 23-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 TON_1821 1b1ae3cde18a5fbabeb684baf8990514 374 Gene3D G3DSA:3.40.50.2000 1 193 6.4E-20 T 23-10-2018 TON_1821 1b1ae3cde18a5fbabeb684baf8990514 374 Gene3D G3DSA:3.40.50.2000 194 359 8.0E-39 T 23-10-2018 TON_1821 1b1ae3cde18a5fbabeb684baf8990514 374 Pfam PF00534 Glycosyl transferases group 1 183 352 3.4E-34 T 23-10-2018 IPR001296 Glycosyl transferase, family 1 TON_1229 e4e3eb5d9639664e23cbe6418c8441c6 139 Pfam PF04027 Domain of unknown function (DUF371) 6 136 3.0E-50 T 23-10-2018 IPR007171 Protein of unknown function DUF371 TON_1229 e4e3eb5d9639664e23cbe6418c8441c6 139 Gene3D G3DSA:2.60.120.630 1 139 2.6E-53 T 23-10-2018 IPR023131 Mth639-like domain superfamily TON_0242 f66ee47f8ee1ab357dea6f7f98eb5a26 219 Pfam PF02361 Cobalt transport protein 6 193 1.8E-28 T 23-10-2018 IPR003339 ABC/ECF transporter, transmembrane component TON_1305 2a836bc085faf6ba7ce02650abc97159 167 SUPERFAMILY SSF55729 1 154 4.39E-30 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase TON_1305 2a836bc085faf6ba7ce02650abc97159 167 Pfam PF00583 Acetyltransferase (GNAT) family 40 141 6.7E-20 T 23-10-2018 IPR000182 GNAT domain TON_1305 2a836bc085faf6ba7ce02650abc97159 167 Gene3D G3DSA:3.40.630.30 1 159 6.1E-51 T 23-10-2018 TON_1340 ae6cace8b9bd32127e5b1c41a0116696 212 Gene3D G3DSA:3.40.50.11570 6 207 4.1E-15 T 23-10-2018 TON_1340 ae6cace8b9bd32127e5b1c41a0116696 212 Pfam PF03192 Pyrococcus protein of unknown function, DUF257 15 197 1.5E-12 T 23-10-2018 IPR005489 Protein of unknown function DUF257 TON_1547 81e9c9c4d0432f3cc307df384e7c1ee8 284 Pfam PF12679 ABC-2 family transporter protein 80 283 6.4E-17 T 23-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 TON_0833 15f7ff3d5626c86fa2e13a08453a3253 118 SUPERFAMILY SSF53335 1 81 2.26E-12 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TON_0833 15f7ff3d5626c86fa2e13a08453a3253 118 Pfam PF13847 Methyltransferase domain 1 86 2.7E-7 T 23-10-2018 IPR025714 Methyltransferase domain TON_0833 15f7ff3d5626c86fa2e13a08453a3253 118 Gene3D G3DSA:3.40.50.150 1 112 1.7E-14 T 23-10-2018 TON_0481 0f003d7fbafbf7c5e8d94296771bf0f4 359 Gene3D G3DSA:3.90.230.10 143 359 1.9E-41 T 23-10-2018 TON_0481 0f003d7fbafbf7c5e8d94296771bf0f4 359 Pfam PF01321 Creatinase/Prolidase N-terminal domain 12 143 1.5E-11 T 23-10-2018 IPR000587 Creatinase, N-terminal GO:0016787 TON_0481 0f003d7fbafbf7c5e8d94296771bf0f4 359 SUPERFAMILY SSF55920 142 359 3.79E-43 T 23-10-2018 IPR036005 Creatinase/aminopeptidase-like TON_0481 0f003d7fbafbf7c5e8d94296771bf0f4 359 SUPERFAMILY SSF53092 7 142 5.76E-23 T 23-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal TON_0481 0f003d7fbafbf7c5e8d94296771bf0f4 359 Gene3D G3DSA:3.40.350.10 9 142 2.9E-19 T 23-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal TON_0481 0f003d7fbafbf7c5e8d94296771bf0f4 359 Pfam PF00557 Metallopeptidase family M24 151 351 4.8E-30 T 23-10-2018 IPR000994 Peptidase M24 TON_0705 6381aefc0f2bc6d9b5dbaccd2a2d3475 290 Gene3D G3DSA:3.30.2010.10 61 151 1.9E-33 T 23-10-2018 TON_0705 6381aefc0f2bc6d9b5dbaccd2a2d3475 290 Hamap MF_00188 Protease HtpX [htpX]. 6 282 30.948 T 23-10-2018 IPR022919 Peptidase M48, protease HtpX, putative GO:0004222 TON_0705 6381aefc0f2bc6d9b5dbaccd2a2d3475 290 Pfam PF01435 Peptidase family M48 68 282 2.3E-37 T 23-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 TON_1045 311c9ceda956a5fc389e6228573f59a9 260 PRINTS PR00377 Inositol monophosphatase superfamily signature 201 225 3.3E-27 T 23-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 TON_1045 311c9ceda956a5fc389e6228573f59a9 260 PRINTS PR00377 Inositol monophosphatase superfamily signature 133 156 3.3E-27 T 23-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 TON_1045 311c9ceda956a5fc389e6228573f59a9 260 PRINTS PR00377 Inositol monophosphatase superfamily signature 168 189 3.3E-27 T 23-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 TON_1045 311c9ceda956a5fc389e6228573f59a9 260 PRINTS PR00377 Inositol monophosphatase superfamily signature 44 64 3.3E-27 T 23-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 TON_1045 311c9ceda956a5fc389e6228573f59a9 260 PRINTS PR00377 Inositol monophosphatase superfamily signature 84 100 3.3E-27 T 23-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 TON_1045 311c9ceda956a5fc389e6228573f59a9 260 Gene3D G3DSA:3.30.540.10 6 143 2.2E-36 T 23-10-2018 TON_1045 311c9ceda956a5fc389e6228573f59a9 260 Gene3D G3DSA:3.40.190.80 148 257 1.1E-28 T 23-10-2018 TON_1045 311c9ceda956a5fc389e6228573f59a9 260 Pfam PF00459 Inositol monophosphatase family 11 255 7.6E-37 T 23-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 TON_1045 311c9ceda956a5fc389e6228573f59a9 260 SUPERFAMILY SSF56655 11 252 3.93E-57 T 23-10-2018 TON_0697 2eda171200689253c8d8206b3bddcffc 319 SUPERFAMILY SSF47413 127 187 2.02E-12 T 23-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TON_0697 2eda171200689253c8d8206b3bddcffc 319 Hamap MF_00584 Putative HTH-type transcriptional regulatory protein . 3 301 28.511 T 23-10-2018 IPR020886 Transcription regulator HTH, Cro/C1-type DNA-binding GO:0003700|GO:0006355 TON_0697 2eda171200689253c8d8206b3bddcffc 319 Gene3D G3DSA:1.10.260.40 129 188 3.6E-12 T 23-10-2018 TON_0697 2eda171200689253c8d8206b3bddcffc 319 SMART SM00530 131 186 6.2E-12 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TON_0697 2eda171200689253c8d8206b3bddcffc 319 Pfam PF01381 Helix-turn-helix 132 185 3.8E-12 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TON_0240 441e22c57d78a837029616a5928c62fe 204 Pfam PF01891 Cobalt uptake substrate-specific transmembrane region 2 196 1.9E-61 T 23-10-2018 IPR002751 Metal transport protein CbiM/NikMN GO:0000041|GO:0016021 TON_0240 441e22c57d78a837029616a5928c62fe 204 Gene3D G3DSA:1.10.1760.20 1 197 1.2E-64 T 23-10-2018 TON_1205 a49794bfe3b74588cb5323339038b72c 427 Gene3D G3DSA:2.130.10.10 174 415 8.2E-18 T 23-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 TON_1205 a49794bfe3b74588cb5323339038b72c 427 Pfam PF13360 PQQ-like domain 255 397 2.1E-9 T 23-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat TON_1205 a49794bfe3b74588cb5323339038b72c 427 TIGRFAM TIGR04288 CGP_CTERM: CGP-CTERM domain 407 426 5.3E-7 T 23-10-2018 IPR027552 CGP-CTERM domain TON_1205 a49794bfe3b74588cb5323339038b72c 427 SMART SM00564 374 406 860.0 T 23-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat TON_1205 a49794bfe3b74588cb5323339038b72c 427 SMART SM00564 238 272 25.0 T 23-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat TON_1205 a49794bfe3b74588cb5323339038b72c 427 SMART SM00564 320 367 14.0 T 23-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat TON_1205 a49794bfe3b74588cb5323339038b72c 427 SMART SM00564 46 92 150.0 T 23-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat TON_1205 a49794bfe3b74588cb5323339038b72c 427 SMART SM00564 189 230 730.0 T 23-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat TON_1205 a49794bfe3b74588cb5323339038b72c 427 SMART SM00564 278 313 9.3 T 23-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat TON_1205 a49794bfe3b74588cb5323339038b72c 427 SUPERFAMILY SSF50998 45 397 5.18E-15 T 23-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily TON_1779 df0d25bbbef58aab007b1fb1770dec8d 249 SUPERFAMILY SSF52540 7 244 2.48E-44 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_1779 df0d25bbbef58aab007b1fb1770dec8d 249 Pfam PF06745 KaiC 10 246 5.6E-77 T 23-10-2018 IPR014774 KaiC-like domain TON_1779 df0d25bbbef58aab007b1fb1770dec8d 249 Gene3D G3DSA:3.40.50.300 2 249 1.2E-73 T 23-10-2018 TON_1508 b1074b1fe04fe1f6d8653eaea1cd0555 211 Pfam PF04252 Predicted SAM-dependent RNA methyltransferase 4 187 3.1E-47 T 23-10-2018 IPR007364 RNA methyltransferase TK0422/Sfm1 GO:0008168 TON_0191 621166f7e48146e2352052976d7a26c4 833 Gene3D G3DSA:3.40.50.2000 408 733 1.5E-42 T 23-10-2018 TON_0191 621166f7e48146e2352052976d7a26c4 833 Gene3D G3DSA:3.40.50.2000 270 407 6.7E-9 T 23-10-2018 TON_0191 621166f7e48146e2352052976d7a26c4 833 ProSitePatterns PS00102 Phosphorylase pyridoxal-phosphate attachment site. 587 599 - T 23-10-2018 IPR035090 Phosphorylase pyridoxal-phosphate attachment site KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 TON_0191 621166f7e48146e2352052976d7a26c4 833 Pfam PF00343 Carbohydrate phosphorylase 273 613 8.1E-26 T 23-10-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 TON_0191 621166f7e48146e2352052976d7a26c4 833 Pfam PF00343 Carbohydrate phosphorylase 127 175 4.6E-5 T 23-10-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 TON_0191 621166f7e48146e2352052976d7a26c4 833 Gene3D G3DSA:3.40.50.2000 117 185 6.0E-11 T 23-10-2018 TON_0191 621166f7e48146e2352052976d7a26c4 833 SUPERFAMILY SSF53756 18 727 2.69E-205 T 23-10-2018 TON_0191 621166f7e48146e2352052976d7a26c4 833 Pfam PF11897 Protein of unknown function (DUF3417) 16 123 2.5E-32 T 23-10-2018 IPR024517 Glycogen phosphorylase, domain of unknown function DUF3417 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238 TON_0191 621166f7e48146e2352052976d7a26c4 833 TIGRFAM TIGR02094 more_P_ylases: alpha-glucan phosphorylases 110 693 3.2E-252 T 23-10-2018 IPR011834 Alpha-glucan phosphorylase GO:0004645|GO:0005975|GO:0030170 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238 TON_0191 621166f7e48146e2352052976d7a26c4 833 PIRSF PIRSF000460 3 770 2.0E-270 T 23-10-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 TON_1816 fb355fe9ae737f668fc74a373a7198b0 910 SUPERFAMILY SSF48168 9 155 1.15E-12 T 23-10-2018 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TON_1816 fb355fe9ae737f668fc74a373a7198b0 910 Pfam PF03477 ATP cone domain 5 93 3.3E-21 T 23-10-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 TON_1816 fb355fe9ae737f668fc74a373a7198b0 910 Gene3D G3DSA:3.20.70.20 72 170 3.0E-6 T 23-10-2018 TON_1816 fb355fe9ae737f668fc74a373a7198b0 910 PRINTS PR01183 Ribonucleotide reductase large chain signature 493 516 3.6E-31 T 23-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TON_1816 fb355fe9ae737f668fc74a373a7198b0 910 PRINTS PR01183 Ribonucleotide reductase large chain signature 559 582 3.6E-31 T 23-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TON_1816 fb355fe9ae737f668fc74a373a7198b0 910 PRINTS PR01183 Ribonucleotide reductase large chain signature 531 553 3.6E-31 T 23-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TON_1816 fb355fe9ae737f668fc74a373a7198b0 910 PRINTS PR01183 Ribonucleotide reductase large chain signature 624 651 3.6E-31 T 23-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TON_1816 fb355fe9ae737f668fc74a373a7198b0 910 PRINTS PR01183 Ribonucleotide reductase large chain signature 346 365 3.6E-31 T 23-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TON_1816 fb355fe9ae737f668fc74a373a7198b0 910 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 113 268 3.2E-29 T 23-10-2018 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TON_1816 fb355fe9ae737f668fc74a373a7198b0 910 Gene3D G3DSA:3.20.70.20 204 786 4.4E-202 T 23-10-2018 TON_1816 fb355fe9ae737f668fc74a373a7198b0 910 TIGRFAM TIGR02504 NrdJ_Z: ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent 120 780 9.6E-232 T 23-10-2018 IPR013344 Ribonucleotide reductase, adenosylcobalamin-dependent GO:0000166|GO:0004748|GO:0031419|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TON_1816 fb355fe9ae737f668fc74a373a7198b0 910 Pfam PF02867 Ribonucleotide reductase, barrel domain 271 771 2.3E-236 T 23-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TON_1816 fb355fe9ae737f668fc74a373a7198b0 910 SUPERFAMILY SSF51998 270 782 3.2E-154 T 23-10-2018 TON_1332 d1a0f60ac94eed5f53ae8a699bfae474 90 Pfam PF04066 Multiple resistance and pH regulation protein F (MrpF / PhaF) 32 84 1.9E-15 T 23-10-2018 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 TON_1126 638e38382f359eebef7672ec308710ba 46 Gene3D G3DSA:3.60.15.10 1 46 1.6E-7 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TON_1267 1e1ae515e028e3776bf29c9a0f667d80 90 Gene3D G3DSA:1.10.10.1100 1 67 2.7E-20 T 23-10-2018 TON_1267 1e1ae515e028e3776bf29c9a0f667d80 90 Pfam PF04324 BFD-like [2Fe-2S] binding domain 6 58 1.5E-12 T 23-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain TON_1564 590572bcfeec97aac64ee6985a3708d3 166 Gene3D G3DSA:3.30.70.20 31 162 1.9E-39 T 23-10-2018 TON_1564 590572bcfeec97aac64ee6985a3708d3 166 Pfam PF13247 4Fe-4S dicluster domain 42 135 1.0E-24 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TON_1564 590572bcfeec97aac64ee6985a3708d3 166 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 80 91 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TON_1564 590572bcfeec97aac64ee6985a3708d3 166 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 13 24 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TON_1564 590572bcfeec97aac64ee6985a3708d3 166 PRINTS PR00354 7Fe ferredoxin signature 58 68 8.0E-5 T 23-10-2018 IPR000813 7Fe ferredoxin GO:0009055 TON_1564 590572bcfeec97aac64ee6985a3708d3 166 PRINTS PR00354 7Fe ferredoxin signature 75 92 8.0E-5 T 23-10-2018 IPR000813 7Fe ferredoxin GO:0009055 TON_1564 590572bcfeec97aac64ee6985a3708d3 166 PRINTS PR00354 7Fe ferredoxin signature 48 58 8.0E-5 T 23-10-2018 IPR000813 7Fe ferredoxin GO:0009055 TON_1564 590572bcfeec97aac64ee6985a3708d3 166 SUPERFAMILY SSF54862 1 150 4.08E-52 T 23-10-2018 TON_1970 18d9167a86fe7b1a645ed6b7c260d071 115 SUPERFAMILY SSF49777 53 97 2.88E-5 T 23-10-2018 IPR036610 PEBP-like superfamily TON_0347 d615fc8412daf83977c1ac745efa02e7 235 Gene3D G3DSA:3.90.1070.10 85 152 2.2E-73 T 23-10-2018 TON_0347 d615fc8412daf83977c1ac745efa02e7 235 Pfam PF08282 haloacid dehalogenase-like hydrolase 5 82 2.5E-8 T 23-10-2018 TON_0347 d615fc8412daf83977c1ac745efa02e7 235 Pfam PF08282 haloacid dehalogenase-like hydrolase 139 218 1.5E-17 T 23-10-2018 TON_0347 d615fc8412daf83977c1ac745efa02e7 235 Hamap MF_01419 Phosphoglycolate phosphatase. 2 228 32.232 T 23-10-2018 IPR006382 Phosphoglycolate phosphatase GO:0000287|GO:0008967|GO:0016311 KEGG: 00630+3.1.3.18|MetaCyc: PWY-181 TON_0347 d615fc8412daf83977c1ac745efa02e7 235 TIGRFAM TIGR01482 SPP-subfamily: sucrose-phosphate phosphatase subfamily 5 231 5.7E-70 T 23-10-2018 TON_0347 d615fc8412daf83977c1ac745efa02e7 235 TIGRFAM TIGR01487 Pglycolate_arch: phosphoglycolate phosphatase, TA0175-type 2 222 4.9E-75 T 23-10-2018 TON_0347 d615fc8412daf83977c1ac745efa02e7 235 Gene3D G3DSA:3.40.50.1000 3 222 2.2E-73 T 23-10-2018 IPR023214 HAD superfamily TON_0347 d615fc8412daf83977c1ac745efa02e7 235 SUPERFAMILY SSF56784 1 227 5.74E-42 T 23-10-2018 IPR036412 HAD-like superfamily TON_0312 9a56ad89f481a120fe3fa8d18aaef41b 461 Pfam PF01554 MatE 256 416 1.5E-31 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 TON_0312 9a56ad89f481a120fe3fa8d18aaef41b 461 Pfam PF01554 MatE 31 190 9.0E-35 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 TON_0312 9a56ad89f481a120fe3fa8d18aaef41b 461 TIGRFAM TIGR00797 matE: MATE efflux family protein 31 429 1.4E-82 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 TON_0312 9a56ad89f481a120fe3fa8d18aaef41b 461 PIRSF PIRSF006603 6 461 5.8E-152 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 TON_1617 fe758a79f7e8841225ac75eaef8c11e4 162 Pfam PF04008 Adenosine specific kinase 7 160 4.4E-63 T 23-10-2018 IPR007153 Adenosine specific kinase TON_1617 fe758a79f7e8841225ac75eaef8c11e4 162 Gene3D G3DSA:3.40.1520.10 1 162 7.2E-73 T 23-10-2018 IPR036902 Ta1353-like superfamily TON_1617 fe758a79f7e8841225ac75eaef8c11e4 162 SUPERFAMILY SSF103165 2 160 3.92E-61 T 23-10-2018 IPR036902 Ta1353-like superfamily TON_0928 f4941fbc38d30bc4ac31d9fec2fde7a4 118 Pfam PF02001 Protein of unknown function DUF134 13 102 4.6E-25 T 23-10-2018 IPR002852 Uncharacterised protein family UPF0251 TON_0928 f4941fbc38d30bc4ac31d9fec2fde7a4 118 Hamap MF_00674 UPF0251 protein . 14 111 23.605 T 23-10-2018 IPR002852 Uncharacterised protein family UPF0251 TON_0928 f4941fbc38d30bc4ac31d9fec2fde7a4 118 Gene3D G3DSA:1.10.10.10 47 96 1.6E-10 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TON_0928 f4941fbc38d30bc4ac31d9fec2fde7a4 118 SUPERFAMILY SSF88659 49 95 6.73E-9 T 23-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like TON_0704 76891e838bd2214f38fb68c8b95cc7a5 380 SUPERFAMILY SSF51338 7 377 2.65E-6 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 TON_0704 76891e838bd2214f38fb68c8b95cc7a5 380 Pfam PF01979 Amidohydrolase family 242 371 7.9E-13 T 23-10-2018 IPR006680 Amidohydrolase-related GO:0016787 TON_0704 76891e838bd2214f38fb68c8b95cc7a5 380 SUPERFAMILY SSF51556 49 342 1.99E-29 T 23-10-2018 IPR032466 Metal-dependent hydrolase TON_0704 76891e838bd2214f38fb68c8b95cc7a5 380 Gene3D G3DSA:3.20.20.140 50 338 2.7E-75 T 23-10-2018 TON_0704 76891e838bd2214f38fb68c8b95cc7a5 380 Gene3D G3DSA:2.30.40.10 16 372 2.7E-75 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 TON_1155 d8a5a5b104555f6aa296b5d18914974f 145 Gene3D G3DSA:1.10.10.10 54 134 1.3E-6 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TON_1155 d8a5a5b104555f6aa296b5d18914974f 145 SUPERFAMILY SSF46785 57 129 5.37E-8 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TON_0682 5a45d33f7bc2e39fde1bea126e5d38bd 213 SUPERFAMILY SSF52402 2 209 1.31E-48 T 23-10-2018 TON_0682 5a45d33f7bc2e39fde1bea126e5d38bd 213 Pfam PF01902 Diphthamide synthase 2 211 1.4E-33 T 23-10-2018 IPR002761 Diphthamide synthase domain MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 TON_0682 5a45d33f7bc2e39fde1bea126e5d38bd 213 Gene3D G3DSA:3.40.50.620 1 116 1.5E-11 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TON_0682 5a45d33f7bc2e39fde1bea126e5d38bd 213 Gene3D G3DSA:3.90.1490.10 117 211 1.6E-13 T 23-10-2018 TON_1777 27e50d011caef6ac9456a771dd55e6dc 346 Pfam PF01896 DNA primase small subunit 96 306 8.3E-14 T 23-10-2018 IPR002755 DNA primase, small subunit GO:0003896|GO:0006269 Reactome: R-HSA-113501|Reactome: R-HSA-174411|Reactome: R-HSA-174430|Reactome: R-HSA-68952|Reactome: R-HSA-68962|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183 TON_1777 27e50d011caef6ac9456a771dd55e6dc 346 Gene3D G3DSA:1.10.8.160 176 277 1.0E-122 T 23-10-2018 TON_1777 27e50d011caef6ac9456a771dd55e6dc 346 Hamap MF_00700 DNA primase small subunit PriS [priS]. 11 343 23.729 T 23-10-2018 IPR023639 DNA primase small subunit PriS GO:0003896 TON_1777 27e50d011caef6ac9456a771dd55e6dc 346 Gene3D G3DSA:3.90.920.10 9 326 1.0E-122 T 23-10-2018 TON_1777 27e50d011caef6ac9456a771dd55e6dc 346 TIGRFAM TIGR00335 primase_sml: putative DNA primase, eukaryotic-type, small subunit 12 329 9.0E-58 T 23-10-2018 IPR014052 DNA primase, small subunit, eukaryotic/archaeal GO:0003896|GO:0006269 Reactome: R-HSA-113501|Reactome: R-HSA-174411|Reactome: R-HSA-174430|Reactome: R-HSA-68952|Reactome: R-HSA-68962|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183 TON_1777 27e50d011caef6ac9456a771dd55e6dc 346 SUPERFAMILY SSF56747 6 341 2.18E-95 T 23-10-2018 TON_0659 49becaabcce3ba121ebcad60ab09e046 413 Pfam PF00483 Nucleotidyl transferase 2 230 1.7E-47 T 23-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 TON_0659 49becaabcce3ba121ebcad60ab09e046 413 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 313 346 0.0016 T 23-10-2018 IPR001451 Hexapeptide repeat TON_0659 49becaabcce3ba121ebcad60ab09e046 413 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 262 289 2.6E-4 T 23-10-2018 IPR001451 Hexapeptide repeat TON_0659 49becaabcce3ba121ebcad60ab09e046 413 Gene3D G3DSA:3.90.550.10 1 238 2.5E-76 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TON_0659 49becaabcce3ba121ebcad60ab09e046 413 SUPERFAMILY SSF53448 1 299 1.53E-75 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TON_0659 49becaabcce3ba121ebcad60ab09e046 413 Gene3D G3DSA:2.160.10.10 239 371 7.9E-18 T 23-10-2018 TON_1400 761c0a0536f6a6f86ff750619f7498dd 188 Gene3D G3DSA:3.30.930.10 1 188 1.3E-72 T 23-10-2018 TON_1400 761c0a0536f6a6f86ff750619f7498dd 188 ProDom PD022700 PH0223 5/5 GENOME PF0133 SEGMENT UNCHARACTERIZED MA4198 MJ0805 4 186 6.0E-88 T 23-10-2018 IPR007162 Protein of unknown function DUF366 TON_1400 761c0a0536f6a6f86ff750619f7498dd 188 Pfam PF04017 Domain of unknown function (DUF366) 5 185 8.1E-69 T 23-10-2018 IPR007162 Protein of unknown function DUF366 TON_1400 761c0a0536f6a6f86ff750619f7498dd 188 PIRSF PIRSF006503 1 188 5.8E-83 T 23-10-2018 IPR007162 Protein of unknown function DUF366 TON_1400 761c0a0536f6a6f86ff750619f7498dd 188 SUPERFAMILY SSF55681 3 186 2.61E-73 T 23-10-2018 TON_0188 1eb27ef07eb13324336849ca6df3180f 464 SUPERFAMILY SSF56731 199 310 4.71E-11 T 23-10-2018 TON_0188 1eb27ef07eb13324336849ca6df3180f 464 SMART SM00493 200 269 2.0E-12 T 23-10-2018 IPR006171 TOPRIM domain TON_0188 1eb27ef07eb13324336849ca6df3180f 464 Gene3D G3DSA:3.40.1360.10 198 295 9.6E-13 T 23-10-2018 TON_0188 1eb27ef07eb13324336849ca6df3180f 464 Pfam PF13662 Toprim domain 201 284 1.3E-12 T 23-10-2018 IPR006171 TOPRIM domain TON_0188 1eb27ef07eb13324336849ca6df3180f 464 Hamap MF_00007 DNA primase DnaG [dnaG]. 36 463 36.374 T 23-10-2018 IPR020607 DNA primase DnaG, archaea GO:0000178|GO:0003896|GO:0008143 TON_0345 ad76b44569085fedfc0bc3c07688513f 118 TIGRFAM TIGR00283 arch_pth2: peptidyl-tRNA hydrolase 5 117 3.0E-44 T 23-10-2018 IPR002833 Peptidyl-tRNA hydrolase, PTH2 GO:0004045 MetaCyc: PWY-6308 TON_0345 ad76b44569085fedfc0bc3c07688513f 118 Gene3D G3DSA:3.40.1490.10 1 118 2.3E-48 T 23-10-2018 IPR023476 Peptidyl-tRNA hydrolase II domain superfamily MetaCyc: PWY-6308 TON_0345 ad76b44569085fedfc0bc3c07688513f 118 Hamap MF_00628 Peptidyl-tRNA hydrolase [pth]. 4 118 29.96 T 23-10-2018 IPR034759 Peptidyl-tRNA hydrolase, archaea GO:0004045 MetaCyc: PWY-6308 TON_0345 ad76b44569085fedfc0bc3c07688513f 118 SUPERFAMILY SSF102462 3 118 9.94E-44 T 23-10-2018 IPR023476 Peptidyl-tRNA hydrolase II domain superfamily MetaCyc: PWY-6308 TON_0345 ad76b44569085fedfc0bc3c07688513f 118 Pfam PF01981 Peptidyl-tRNA hydrolase PTH2 4 117 1.0E-45 T 23-10-2018 IPR002833 Peptidyl-tRNA hydrolase, PTH2 GO:0004045 MetaCyc: PWY-6308 TON_0205 8aa3a32d30960da04f063f26fd99a4ee 116 SUPERFAMILY SSF53706 3 60 3.71E-8 T 23-10-2018 TON_0205 8aa3a32d30960da04f063f26fd99a4ee 116 SUPERFAMILY SSF160148 48 115 7.06E-19 T 23-10-2018 IPR036593 CPE0013-like superfamily TON_0205 8aa3a32d30960da04f063f26fd99a4ee 116 Pfam PF07892 Protein of unknown function (DUF1667) 36 114 9.0E-27 T 23-10-2018 IPR012460 Protein of unknown function DUF1667 TON_0205 8aa3a32d30960da04f063f26fd99a4ee 116 Gene3D G3DSA:3.10.530.10 48 114 1.6E-16 T 23-10-2018 IPR036593 CPE0013-like superfamily TON_0889 0bd0818173a9a76cd8dfaa0424376bef 234 SUPERFAMILY SSF52540 1 228 3.21E-40 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_0889 0bd0818173a9a76cd8dfaa0424376bef 234 PRINTS PR01874 DNA repair protein radA signature 13 41 2.9E-11 T 23-10-2018 TON_0889 0bd0818173a9a76cd8dfaa0424376bef 234 PRINTS PR01874 DNA repair protein radA signature 55 72 2.9E-11 T 23-10-2018 TON_0889 0bd0818173a9a76cd8dfaa0424376bef 234 Pfam PF06745 KaiC 4 229 7.1E-50 T 23-10-2018 IPR014774 KaiC-like domain TON_0889 0bd0818173a9a76cd8dfaa0424376bef 234 Gene3D G3DSA:3.40.50.300 1 231 1.2E-56 T 23-10-2018 TON_0080 4520627ba3242f5f7641c61ce56aea22 56 ProSitePatterns PS00527 Ribosomal protein S14 signature. 23 44 - T 23-10-2018 IPR018271 Ribosomal protein S14, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0080 4520627ba3242f5f7641c61ce56aea22 56 Hamap MF_01364_A 30S ribosomal protein S14 type Z [rpsZ]. 2 56 17.461 T 23-10-2018 IPR023676 Ribosomal protein S14, type Z, archaeal GO:0003723|GO:0003735|GO:0006412|GO:0015935 TON_0080 4520627ba3242f5f7641c61ce56aea22 56 Gene3D G3DSA:4.10.830.10 1 56 2.2E-20 T 23-10-2018 TON_0080 4520627ba3242f5f7641c61ce56aea22 56 Pfam PF00253 Ribosomal protein S14p/S29e 8 55 1.9E-9 T 23-10-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TON_1541 ae809400ec1c43ecaa2710e15d682696 440 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 8 415 4.1E-50 T 23-10-2018 IPR002823 Protein of unknown function DUF112, transmembrane TON_0796 5b1715e0d1eadf004b59a454a8e8b029 126 Pfam PF02641 Uncharacterized ACR, COG1993 12 104 3.1E-38 T 23-10-2018 IPR003793 Domain of unknown function DUF190 TON_0796 5b1715e0d1eadf004b59a454a8e8b029 126 Gene3D G3DSA:3.30.70.120 1 126 4.6E-56 T 23-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal TON_0796 5b1715e0d1eadf004b59a454a8e8b029 126 SUPERFAMILY SSF54913 8 104 7.12E-34 T 23-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta TON_1134 b454f5c34a6ed2d239467b864a6031c8 325 SUPERFAMILY SSF56796 7 323 2.62E-85 T 23-10-2018 TON_1134 b454f5c34a6ed2d239467b864a6031c8 325 Gene3D G3DSA:3.40.50.1970 3 153 3.9E-46 T 23-10-2018 TON_1134 b454f5c34a6ed2d239467b864a6031c8 325 Gene3D G3DSA:1.20.1090.10 154 324 5.4E-43 T 23-10-2018 TON_1134 b454f5c34a6ed2d239467b864a6031c8 325 Pfam PF01761 3-dehydroquinate synthase 49 291 8.2E-78 T 23-10-2018 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 TON_1134 b454f5c34a6ed2d239467b864a6031c8 325 PIRSF PIRSF001455 8 325 3.8E-92 T 23-10-2018 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 TON_0720 aa5f478bad26d41044723d4e0c496f70 280 SUPERFAMILY SSF103481 183 272 1.57E-5 T 23-10-2018 TON_0720 aa5f478bad26d41044723d4e0c496f70 280 Pfam PF00892 EamA-like transporter family 6 140 1.2E-19 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TON_0720 aa5f478bad26d41044723d4e0c496f70 280 Pfam PF00892 EamA-like transporter family 149 270 7.1E-12 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TON_0720 aa5f478bad26d41044723d4e0c496f70 280 SUPERFAMILY SSF103481 45 143 5.23E-12 T 23-10-2018 TON_1071 51e0b36d6f47762a5af0a553ffe11ba6 220 Gene3D G3DSA:1.10.10.580 147 216 8.1E-36 T 23-10-2018 IPR023093 ScpA-like, C-terminal TON_1071 51e0b36d6f47762a5af0a553ffe11ba6 220 Pfam PF02616 Segregation and condensation protein ScpA 18 162 8.5E-13 T 23-10-2018 IPR003768 Segregation and condensation protein A TON_1339 654e80ed39f8e01c381d4351da393fba 253 Gene3D G3DSA:3.40.50.150 63 253 4.7E-68 T 23-10-2018 TON_1339 654e80ed39f8e01c381d4351da393fba 253 Gene3D G3DSA:3.10.330.20 1 61 1.9E-22 T 23-10-2018 TON_1339 654e80ed39f8e01c381d4351da393fba 253 SUPERFAMILY SSF53335 2 252 1.7E-76 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TON_1339 654e80ed39f8e01c381d4351da393fba 253 Pfam PF08704 tRNA methyltransferase complex GCD14 subunit 74 234 4.0E-27 T 23-10-2018 IPR014816 tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 GO:0016429|GO:0030488|GO:0031515 MetaCyc: PWY-6829 TON_1339 654e80ed39f8e01c381d4351da393fba 253 PIRSF PIRSF017269 1 253 2.1E-78 T 23-10-2018 IPR014816 tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 GO:0016429|GO:0030488|GO:0031515 MetaCyc: PWY-6829 TON_1528 dbf4a56df98a6a693d5d14921655344b 83 ProDom PD029943 UPF0147 ARCHAEAL PF0239 ST0460.1 MM1385 CYTOSOLIC SACI_0891 TV0625 APES069 TA0600 1 83 7.0E-39 T 23-10-2018 IPR005354 Uncharacterised protein family UPF0147 TON_1528 dbf4a56df98a6a693d5d14921655344b 83 Pfam PF03685 Uncharacterised protein family (UPF0147) 2 82 3.6E-33 T 23-10-2018 IPR005354 Uncharacterised protein family UPF0147 TON_1528 dbf4a56df98a6a693d5d14921655344b 83 SUPERFAMILY SSF158436 3 83 8.11E-30 T 23-10-2018 TON_1528 dbf4a56df98a6a693d5d14921655344b 83 Gene3D G3DSA:1.20.1440.50 2 83 5.4E-31 T 23-10-2018 IPR023130 Ta0600-like superfamily TON_1528 dbf4a56df98a6a693d5d14921655344b 83 Hamap MF_00342 UPF0147 protein . 1 83 29.668 T 23-10-2018 IPR005354 Uncharacterised protein family UPF0147 TON_0598 dd6a5f4badb92a154c2eaef31a26c40a 327 Pfam PF01297 Zinc-uptake complex component A periplasmic 29 264 5.8E-32 T 23-10-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 TON_0598 dd6a5f4badb92a154c2eaef31a26c40a 327 Gene3D G3DSA:3.40.50.1980 25 186 4.4E-29 T 23-10-2018 TON_0598 dd6a5f4badb92a154c2eaef31a26c40a 327 SUPERFAMILY SSF53807 25 289 3.09E-41 T 23-10-2018 TON_1790 b46055bab27ef1ac5a97c69d672107e5 134 SUPERFAMILY SSF53335 5 85 6.98E-6 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TON_1790 b46055bab27ef1ac5a97c69d672107e5 134 ProDom PD021130 UPF0146 MJ0688 SIMILAR ARCHAEA UNCHARACTERIZED AF0739.1 MTH1000 PYRAB01940 PH0209 VNG2609C 19 112 4.0E-40 T 23-10-2018 IPR005353 Uncharacterised protein family UPF0146 TON_1790 b46055bab27ef1ac5a97c69d672107e5 134 Gene3D G3DSA:3.40.50.150 3 134 1.6E-24 T 23-10-2018 TON_1790 b46055bab27ef1ac5a97c69d672107e5 134 Hamap MF_00341 UPF0146 protein . 3 132 25.913 T 23-10-2018 IPR005353 Uncharacterised protein family UPF0146 TON_1790 b46055bab27ef1ac5a97c69d672107e5 134 Pfam PF03686 Uncharacterised protein family (UPF0146) 4 131 6.4E-29 T 23-10-2018 IPR005353 Uncharacterised protein family UPF0146 TON_1542 6ed9a6fc30b3487cdd73a4f868045a4c 991 Pfam PF01336 OB-fold nucleic acid binding domain 918 981 2.7E-6 T 23-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 TON_1542 6ed9a6fc30b3487cdd73a4f868045a4c 991 Gene3D G3DSA:2.40.50.140 902 988 1.0E-6 T 23-10-2018 TON_1542 6ed9a6fc30b3487cdd73a4f868045a4c 991 SUPERFAMILY SSF50249 916 983 5.82E-6 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold TON_1542 6ed9a6fc30b3487cdd73a4f868045a4c 991 SUPERFAMILY SSF50249 361 438 5.71E-5 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold TON_0601 a9c3dbac3e3ad42937751d4702a3c52d 215 Gene3D G3DSA:3.40.50.2020 6 180 3.1E-41 T 23-10-2018 TON_0601 a9c3dbac3e3ad42937751d4702a3c52d 215 Pfam PF00156 Phosphoribosyl transferase domain 17 152 2.2E-20 T 23-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 TON_0601 a9c3dbac3e3ad42937751d4702a3c52d 215 SUPERFAMILY SSF53271 7 160 4.85E-37 T 23-10-2018 IPR029057 Phosphoribosyltransferase-like TON_0068 e207c9d23c547acb8694581e23703f27 86 Hamap MF_01369_A 50S ribosomal protein L23 [rplW]. 6 86 27.83 T 23-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 TON_0068 e207c9d23c547acb8694581e23703f27 86 Gene3D G3DSA:3.30.70.330 1 86 4.1E-37 T 23-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily TON_0068 e207c9d23c547acb8694581e23703f27 86 SUPERFAMILY SSF54189 4 78 2.84E-28 T 23-10-2018 IPR012678 Ribosomal protein L23/L15e core domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 TON_0068 e207c9d23c547acb8694581e23703f27 86 Pfam PF00276 Ribosomal protein L23 5 73 1.5E-19 T 23-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 TON_0068 e207c9d23c547acb8694581e23703f27 86 ProSitePatterns PS00050 Ribosomal protein L23 signature. 64 79 - T 23-10-2018 IPR001014 Ribosomal protein L23/L25, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0068 e207c9d23c547acb8694581e23703f27 86 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 4 82 14.682 T 23-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 TON_0068 e207c9d23c547acb8694581e23703f27 86 TIGRFAM TIGR03636 uL23_arch: ribosomal protein uL23 10 86 8.5E-40 T 23-10-2018 IPR019985 Ribosomal protein L23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_1085 10765c95f97f2fced5988989bf991510 345 Gene3D G3DSA:3.40.50.2000 1 171 8.0E-40 T 23-10-2018 TON_1085 10765c95f97f2fced5988989bf991510 345 Pfam PF13439 Glycosyltransferase Family 4 14 168 3.7E-30 T 23-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 TON_1085 10765c95f97f2fced5988989bf991510 345 Gene3D G3DSA:3.40.50.2000 172 314 2.4E-31 T 23-10-2018 TON_1085 10765c95f97f2fced5988989bf991510 345 SUPERFAMILY SSF53756 5 342 2.48E-74 T 23-10-2018 TON_1085 10765c95f97f2fced5988989bf991510 345 Pfam PF00534 Glycosyl transferases group 1 173 313 9.2E-24 T 23-10-2018 IPR001296 Glycosyl transferase, family 1 TON_1801 20b8e1aa4447b840e60551feff41d9dd 258 ProDom PD359573 MEMBRANE TRANSMEMBRANE AF2132 PROTEIN 38 157 1.0E-16 T 23-10-2018 TON_0194 8211be9231763ebed45272c5bc4943c0 66 Gene3D G3DSA:2.160.10.10 1 66 3.6E-9 T 23-10-2018 TON_0194 8211be9231763ebed45272c5bc4943c0 66 SUPERFAMILY SSF51161 4 65 2.77E-12 T 23-10-2018 IPR011004 Trimeric LpxA-like superfamily TON_0194 8211be9231763ebed45272c5bc4943c0 66 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 7 33 2.5E-4 T 23-10-2018 IPR001451 Hexapeptide repeat TON_1242 da001bfb7bd56f14486d2a6f023eae35 487 PIRSF PIRSF018875 1 486 1.1E-77 T 23-10-2018 IPR018646 Membrane protein of 12 TMs TON_1242 da001bfb7bd56f14486d2a6f023eae35 487 Pfam PF09847 Membrane protein of 12 TMs 40 481 2.5E-79 T 23-10-2018 IPR018646 Membrane protein of 12 TMs TON_1694 22b87f1bb1d55189f96432f8ec7f2e9e 379 Pfam PF13180 PDZ domain 207 274 3.6E-12 T 23-10-2018 IPR001478 PDZ domain GO:0005515 TON_1694 22b87f1bb1d55189f96432f8ec7f2e9e 379 PRINTS PR01000 Sterol regulatory element binding protein site 2 protease (M50) signature 157 169 1.3E-22 T 23-10-2018 IPR001193 Membrane-bound transcription factor site-2 protease GO:0004222|GO:0006508|GO:0016020 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 TON_1694 22b87f1bb1d55189f96432f8ec7f2e9e 379 PRINTS PR01000 Sterol regulatory element binding protein site 2 protease (M50) signature 141 156 1.3E-22 T 23-10-2018 IPR001193 Membrane-bound transcription factor site-2 protease GO:0004222|GO:0006508|GO:0016020 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 TON_1694 22b87f1bb1d55189f96432f8ec7f2e9e 379 PRINTS PR01000 Sterol regulatory element binding protein site 2 protease (M50) signature 105 124 1.3E-22 T 23-10-2018 IPR001193 Membrane-bound transcription factor site-2 protease GO:0004222|GO:0006508|GO:0016020 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 TON_1694 22b87f1bb1d55189f96432f8ec7f2e9e 379 PRINTS PR01000 Sterol regulatory element binding protein site 2 protease (M50) signature 125 139 1.3E-22 T 23-10-2018 IPR001193 Membrane-bound transcription factor site-2 protease GO:0004222|GO:0006508|GO:0016020 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 TON_1694 22b87f1bb1d55189f96432f8ec7f2e9e 379 SMART SM00228 192 265 4.4E-9 T 23-10-2018 IPR001478 PDZ domain GO:0005515 TON_1694 22b87f1bb1d55189f96432f8ec7f2e9e 379 Pfam PF02163 Peptidase family M50 117 366 6.4E-20 T 23-10-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 TON_1694 22b87f1bb1d55189f96432f8ec7f2e9e 379 Gene3D G3DSA:2.30.42.10 205 291 7.6E-23 T 23-10-2018 TON_1694 22b87f1bb1d55189f96432f8ec7f2e9e 379 SUPERFAMILY SSF50156 206 296 1.3E-22 T 23-10-2018 IPR036034 PDZ superfamily GO:0005515 TON_1748 2ac703d4e2b593cfa1bfeabad758f37a 162 SUPERFAMILY SSF81333 6 70 2.09E-10 T 23-10-2018 IPR035921 F/V-ATP synthase subunit C superfamily TON_1748 2ac703d4e2b593cfa1bfeabad758f37a 162 Gene3D G3DSA:1.20.120.610 2 158 1.1E-40 T 23-10-2018 TON_1748 2ac703d4e2b593cfa1bfeabad758f37a 162 Pfam PF00137 ATP synthase subunit C 9 68 1.6E-12 T 23-10-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 TON_1748 2ac703d4e2b593cfa1bfeabad758f37a 162 Pfam PF00137 ATP synthase subunit C 97 155 1.6E-15 T 23-10-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 TON_1748 2ac703d4e2b593cfa1bfeabad758f37a 162 SUPERFAMILY SSF81333 89 156 6.93E-14 T 23-10-2018 IPR035921 F/V-ATP synthase subunit C superfamily TON_1321 03b3464acc36840173688a2fba4a6656 262 Gene3D G3DSA:1.10.357.140 16 158 3.8E-9 T 23-10-2018 TON_1321 03b3464acc36840173688a2fba4a6656 262 Pfam PF01040 UbiA prenyltransferase family 22 235 1.9E-33 T 23-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 TON_1932 743e885cb5d63ce23d216461678d6abe 234 Pfam PF10086 Putative membrane peptidase family (DUF2324) 135 204 4.7E-8 T 23-10-2018 IPR011397 Uncharacterised conserved protein UCP033101 TON_1932 743e885cb5d63ce23d216461678d6abe 234 Pfam PF10086 Putative membrane peptidase family (DUF2324) 24 127 1.5E-6 T 23-10-2018 IPR011397 Uncharacterised conserved protein UCP033101 TON_0861 98edd7644829e22b4ee88d95d964021a 293 SUPERFAMILY SSF52518 19 279 3.16E-79 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold TON_0861 98edd7644829e22b4ee88d95d964021a 293 Pfam PF12367 Pyruvate ferredoxin oxidoreductase beta subunit C terminal 206 267 2.6E-25 T 23-10-2018 IPR032686 Pyruvate ferredoxin oxidoreductase beta subunit, C-terminal TON_0861 98edd7644829e22b4ee88d95d964021a 293 TIGRFAM TIGR02177 PorB_KorB: 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate family 21 287 5.9E-110 T 23-10-2018 IPR011896 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate TON_0861 98edd7644829e22b4ee88d95d964021a 293 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 59 202 4.7E-32 T 23-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 TON_0861 98edd7644829e22b4ee88d95d964021a 293 Gene3D G3DSA:3.40.50.970 77 219 2.4E-25 T 23-10-2018 TON_1239 fa968c74bec8421d106cf65297044eb4 279 Pfam PF00294 pfkB family carbohydrate kinase 174 255 2.0E-5 T 23-10-2018 IPR011611 Carbohydrate kinase PfkB TON_1239 fa968c74bec8421d106cf65297044eb4 279 SUPERFAMILY SSF53613 1 266 1.18E-38 T 23-10-2018 IPR029056 Ribokinase-like TON_1239 fa968c74bec8421d106cf65297044eb4 279 Gene3D G3DSA:3.40.1190.20 1 275 5.7E-94 T 23-10-2018 IPR029056 Ribokinase-like TON_0535 8e650608be854848c916eb56756fbb18 265 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 15 149 2.5E-25 T 23-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_0535 8e650608be854848c916eb56756fbb18 265 Gene3D G3DSA:3.40.50.700 3 163 9.7E-41 T 23-10-2018 IPR037024 [NiFe]-hydrogenase, small subunit, N-terminal domain superfamily TON_0535 8e650608be854848c916eb56756fbb18 265 SUPERFAMILY SSF56770 4 210 1.83E-44 T 23-10-2018 TON_1285 e41fb19e84430d20ebefa33d5ef7ef16 166 Pfam PF01965 DJ-1/PfpI family 1 163 5.7E-58 T 23-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 TON_1285 e41fb19e84430d20ebefa33d5ef7ef16 166 TIGRFAM TIGR01382 PfpI: intracellular protease, PfpI family 2 165 2.7E-67 T 23-10-2018 IPR006286 Deglycase PfpI TON_1285 e41fb19e84430d20ebefa33d5ef7ef16 166 Gene3D G3DSA:3.40.50.880 1 166 3.9E-51 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like TON_1285 e41fb19e84430d20ebefa33d5ef7ef16 166 SUPERFAMILY SSF52317 1 165 1.36E-50 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like TON_1357 33f1d8a6951318a0fe9dbaccd5504d7a 223 Pfam PF01909 Nucleotidyltransferase domain 6 86 6.1E-8 T 23-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 TON_1357 33f1d8a6951318a0fe9dbaccd5504d7a 223 SUPERFAMILY SSF81301 4 83 5.38E-9 T 23-10-2018 TON_1357 33f1d8a6951318a0fe9dbaccd5504d7a 223 Gene3D G3DSA:3.30.460.10 2 89 6.2E-7 T 23-10-2018 TON_0870 1b2e4e7196822e320876138a4a91b69c 116 Gene3D G3DSA:3.30.300.130 23 108 1.8E-14 T 23-10-2018 IPR034904 Fe-S cluster assembly domain superfamily TON_0870 1b2e4e7196822e320876138a4a91b69c 116 Pfam PF01883 Iron-sulfur cluster assembly protein 26 87 2.0E-11 T 23-10-2018 IPR002744 MIP18 family-like TON_0870 1b2e4e7196822e320876138a4a91b69c 116 SUPERFAMILY SSF117916 25 89 4.58E-13 T 23-10-2018 IPR034904 Fe-S cluster assembly domain superfamily TON_1173 cd9fcfac8e1560c3316b5ad363805304 55 Pfam PF04021 Class III signal peptide 3 28 7.3E-8 T 23-10-2018 IPR007166 Class III signal peptide motif TON_1786 5d99424442ec5562c1e83fa8261cb12f 111 Pfam PF05402 Coenzyme PQQ synthesis protein D (PqqD) 44 102 1.8E-16 T 23-10-2018 IPR008792 Coenzyme PQQ synthesis D TON_1786 5d99424442ec5562c1e83fa8261cb12f 111 Gene3D G3DSA:1.10.10.1150 41 103 3.6E-8 T 23-10-2018 TON_1449 447401275b7ff621caebf167100d1bbb 261 PIRSF PIRSF005956 1 259 9.9E-98 T 23-10-2018 IPR005137 Membrane complex biogenesis protein, BtpA family TON_1449 447401275b7ff621caebf167100d1bbb 261 SUPERFAMILY SSF51366 21 254 2.59E-26 T 23-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 TON_1449 447401275b7ff621caebf167100d1bbb 261 Pfam PF03437 BtpA family 5 254 1.2E-107 T 23-10-2018 IPR005137 Membrane complex biogenesis protein, BtpA family TON_1449 447401275b7ff621caebf167100d1bbb 261 ProDom PD011184 BTPA I PHOTOSYSTEM BIOGENESIS ASSEMBLY SGCQ TRIPHOSPHATASE NUCLEOSIDE PAE3553 ENZYME 28 199 7.0E-81 T 23-10-2018 IPR005137 Membrane complex biogenesis protein, BtpA family TON_1449 447401275b7ff621caebf167100d1bbb 261 TIGRFAM TIGR00259 thylakoid_BtpA: membrane complex biogenesis protein, BtpA family 5 255 3.3E-109 T 23-10-2018 IPR005137 Membrane complex biogenesis protein, BtpA family TON_1161 41cce1acecd5a9e38ef5d36d875a3192 194 Pfam PF12710 haloacid dehalogenase-like hydrolase 5 159 8.5E-12 T 23-10-2018 TON_1161 41cce1acecd5a9e38ef5d36d875a3192 194 Gene3D G3DSA:1.10.150.210 14 73 2.6E-76 T 23-10-2018 IPR023190 Phosphoserine phosphatase, domain 2 GO:0004647|GO:0006564 KEGG: 00260+3.1.3.3|KEGG: 00680+3.1.3.3|Reactome: R-HSA-977347 TON_1161 41cce1acecd5a9e38ef5d36d875a3192 194 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 4 162 9.5E-21 T 23-10-2018 TON_1161 41cce1acecd5a9e38ef5d36d875a3192 194 Gene3D G3DSA:3.40.50.1000 3 186 2.6E-76 T 23-10-2018 IPR023214 HAD superfamily TON_1161 41cce1acecd5a9e38ef5d36d875a3192 194 SUPERFAMILY SSF56784 1 192 6.5E-33 T 23-10-2018 IPR036412 HAD-like superfamily TON_1462 9c77d15aac7e4181a1dcdf5c169356be 368 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 93 131 - T 23-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 TON_1462 9c77d15aac7e4181a1dcdf5c169356be 368 SUPERFAMILY SSF53187 4 367 2.1E-53 T 23-10-2018 TON_1462 9c77d15aac7e4181a1dcdf5c169356be 368 SUPERFAMILY SSF55031 166 273 1.06E-11 T 23-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain TON_1462 9c77d15aac7e4181a1dcdf5c169356be 368 Pfam PF01546 Peptidase family M20/M25/M40 61 365 2.8E-28 T 23-10-2018 IPR002933 Peptidase M20 GO:0016787 TON_1462 9c77d15aac7e4181a1dcdf5c169356be 368 Gene3D G3DSA:3.40.630.10 5 356 5.5E-75 T 23-10-2018 TON_1462 9c77d15aac7e4181a1dcdf5c169356be 368 Gene3D G3DSA:3.30.70.360 167 278 5.5E-75 T 23-10-2018 TON_1462 9c77d15aac7e4181a1dcdf5c169356be 368 Pfam PF07687 Peptidase dimerisation domain 164 265 4.7E-10 T 23-10-2018 IPR011650 Peptidase M20, dimerisation domain TON_1164 a1a3cabf3c9a720aaf18971ab78588b3 187 Gene3D G3DSA:3.40.50.620 1 177 3.0E-55 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TON_1164 a1a3cabf3c9a720aaf18971ab78588b3 187 Pfam PF01467 Cytidylyltransferase-like 6 136 5.4E-18 T 23-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 TON_1164 a1a3cabf3c9a720aaf18971ab78588b3 187 TIGRFAM TIGR01527 arch_NMN_Atrans: nicotinamide-nucleotide adenylyltransferase 4 168 2.0E-69 T 23-10-2018 IPR006418 Nicotinamide-nucleotide adenylyltransferase, archaeal type GO:0000309|GO:0005737|GO:0009435 KEGG: 00760+2.7.7.1 TON_1164 a1a3cabf3c9a720aaf18971ab78588b3 187 Hamap MF_00243 Nicotinamide-nucleotide adenylyltransferase. 1 187 92.19 T 23-10-2018 IPR006418 Nicotinamide-nucleotide adenylyltransferase, archaeal type GO:0000309|GO:0005737|GO:0009435 KEGG: 00760+2.7.7.1 TON_1164 a1a3cabf3c9a720aaf18971ab78588b3 187 SUPERFAMILY SSF52374 3 166 7.41E-38 T 23-10-2018 TON_1164 a1a3cabf3c9a720aaf18971ab78588b3 187 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 4 62 2.1E-18 T 23-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 TON_1275 af8c209008ba29137167d1458349e43a 56 SUPERFAMILY SSF56219 10 55 9.29E-10 T 23-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily TON_1275 af8c209008ba29137167d1458349e43a 56 Gene3D G3DSA:3.60.10.10 3 55 3.2E-7 T 23-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily TON_1044 cb2379231d482ef7f0776cbc37bcfc05 202 Pfam PF01694 Rhomboid family 55 188 7.8E-27 T 23-10-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 TON_1044 cb2379231d482ef7f0776cbc37bcfc05 202 SUPERFAMILY SSF144091 9 193 1.09E-38 T 23-10-2018 TON_1044 cb2379231d482ef7f0776cbc37bcfc05 202 Gene3D G3DSA:1.20.1540.10 4 198 7.1E-40 T 23-10-2018 IPR035952 Rhomboid-like superfamily TON_0576 f46b4660f33eb29c50d54567110deb12 282 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 237 248 1.9E-5 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TON_0576 f46b4660f33eb29c50d54567110deb12 282 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 248 267 1.9E-5 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TON_0576 f46b4660f33eb29c50d54567110deb12 282 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 221 237 1.9E-5 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 TON_0576 f46b4660f33eb29c50d54567110deb12 282 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 215 274 1.7E-8 T 23-10-2018 IPR002831 Transcription regulator TrmB, N-terminal TON_0576 f46b4660f33eb29c50d54567110deb12 282 SUPERFAMILY SSF46785 208 274 2.27E-11 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TON_0576 f46b4660f33eb29c50d54567110deb12 282 Gene3D G3DSA:1.10.10.10 204 280 2.2E-9 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TON_1190 9c79d8a5a82431f6a108f74199b11cb3 317 Pfam PF13489 Methyltransferase domain 145 302 5.9E-14 T 23-10-2018 TON_1190 9c79d8a5a82431f6a108f74199b11cb3 317 SUPERFAMILY SSF53335 132 306 1.78E-29 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TON_1190 9c79d8a5a82431f6a108f74199b11cb3 317 Gene3D G3DSA:3.40.50.150 121 313 8.0E-26 T 23-10-2018 TON_0443 cd1c2ce936e241a5bd18a5868c6394b1 278 Gene3D G3DSA:3.20.20.100 10 276 4.4E-87 T 23-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily TON_0443 cd1c2ce936e241a5bd18a5868c6394b1 278 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 137 154 - T 23-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 TON_0443 cd1c2ce936e241a5bd18a5868c6394b1 278 SUPERFAMILY SSF51430 17 272 4.19E-75 T 23-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily TON_0443 cd1c2ce936e241a5bd18a5868c6394b1 278 PIRSF PIRSF000097 10 276 5.8E-37 T 23-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 TON_0443 cd1c2ce936e241a5bd18a5868c6394b1 278 PRINTS PR00069 Aldo-keto reductase signature 49 73 2.7E-19 T 23-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 TON_0443 cd1c2ce936e241a5bd18a5868c6394b1 278 PRINTS PR00069 Aldo-keto reductase signature 212 236 2.7E-19 T 23-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 TON_0443 cd1c2ce936e241a5bd18a5868c6394b1 278 PRINTS PR00069 Aldo-keto reductase signature 105 123 2.7E-19 T 23-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 TON_0443 cd1c2ce936e241a5bd18a5868c6394b1 278 PRINTS PR00069 Aldo-keto reductase signature 137 154 2.7E-19 T 23-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 TON_0443 cd1c2ce936e241a5bd18a5868c6394b1 278 Pfam PF00248 Aldo/keto reductase family 21 276 6.4E-61 T 23-10-2018 IPR023210 NADP-dependent oxidoreductase domain TON_0644 0a5b0960b9b2bdaf8ff5a02069f11960 78 SMART SM00651 7 72 2.6E-21 T 23-10-2018 IPR001163 LSM domain, eukaryotic/archaea-type TON_0644 0a5b0960b9b2bdaf8ff5a02069f11960 78 SUPERFAMILY SSF50182 3 74 6.29E-18 T 23-10-2018 IPR010920 LSM domain superfamily TON_0644 0a5b0960b9b2bdaf8ff5a02069f11960 78 Pfam PF01423 LSM domain 9 72 2.4E-18 T 23-10-2018 IPR001163 LSM domain, eukaryotic/archaea-type TON_0644 0a5b0960b9b2bdaf8ff5a02069f11960 78 Gene3D G3DSA:2.30.30.100 1 74 3.1E-23 T 23-10-2018 TON_0644 0a5b0960b9b2bdaf8ff5a02069f11960 78 Hamap MF_00257 Putative snRNP Sm-like protein. 1 72 25.585 T 23-10-2018 IPR022901 snRNP Sm-like, putative, archaea TON_1672 8540a827a0595dd8198e0f355b900bb1 357 Gene3D G3DSA:1.10.1580.10 170 252 1.1E-13 T 23-10-2018 IPR023179 GTP-binding protein, orthogonal bundle domain superfamily TON_1672 8540a827a0595dd8198e0f355b900bb1 357 Pfam PF01926 50S ribosome-binding GTPase 107 162 5.8E-13 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 TON_1672 8540a827a0595dd8198e0f355b900bb1 357 Gene3D G3DSA:3.40.50.300 5 162 7.2E-46 T 23-10-2018 TON_1672 8540a827a0595dd8198e0f355b900bb1 357 SUPERFAMILY SSF52540 4 168 3.3E-39 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_1749 fe177182df4cc255f493a7e1ef7db740 203 Gene3D G3DSA:1.20.5.620 18 98 1.5E-23 T 23-10-2018 TON_1749 fe177182df4cc255f493a7e1ef7db740 203 SUPERFAMILY SSF160527 82 203 2.48E-25 T 23-10-2018 TON_1749 fe177182df4cc255f493a7e1ef7db740 203 Gene3D G3DSA:3.30.2320.30 100 203 7.4E-19 T 23-10-2018 IPR038495 V-type ATPase subunit E, C-terminal domain superfamily Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TON_1749 fe177182df4cc255f493a7e1ef7db740 203 Hamap MF_00311 V-type proton ATPase subunit E [atpE]. 2 203 15.317 T 23-10-2018 IPR002842 V-type ATPase subunit E GO:0015991|GO:0033178|GO:0046961 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TON_1749 fe177182df4cc255f493a7e1ef7db740 203 Pfam PF01991 ATP synthase (E/31 kDa) subunit 10 202 4.7E-38 T 23-10-2018 IPR002842 V-type ATPase subunit E GO:0015991|GO:0033178|GO:0046961 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TON_1629 0f8f537989e4b9e89bc34c0e245cb3f9 172 Pfam PF11447 Protein of unknown function (DUF3201) 8 158 1.3E-67 T 23-10-2018 IPR024505 Protein of unknown function DUF3201 TON_1629 0f8f537989e4b9e89bc34c0e245cb3f9 172 SUPERFAMILY SSF142913 3 170 7.59E-52 T 23-10-2018 TON_1629 0f8f537989e4b9e89bc34c0e245cb3f9 172 Gene3D G3DSA:3.30.930.10 1 170 6.6E-65 T 23-10-2018 TON_0429 4bd06881f4eec12adb201d233bbdac80 362 SUPERFAMILY SSF51735 1 169 2.57E-22 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TON_0429 4bd06881f4eec12adb201d233bbdac80 362 Gene3D G3DSA:3.30.360.10 118 299 5.8E-132 T 23-10-2018 TON_0429 4bd06881f4eec12adb201d233bbdac80 362 Pfam PF16653 Saccharopine dehydrogenase C-terminal domain 117 349 2.1E-31 T 23-10-2018 IPR032095 Saccharopine dehydrogenase, C-terminal Reactome: R-HSA-71064 TON_0429 4bd06881f4eec12adb201d233bbdac80 362 SUPERFAMILY SSF55347 118 252 7.85E-40 T 23-10-2018 TON_0429 4bd06881f4eec12adb201d233bbdac80 362 Pfam PF03435 Saccharopine dehydrogenase NADP binding domain 3 113 1.6E-19 T 23-10-2018 IPR005097 Saccharopine dehydrogenase, NADP binding domain GO:0016491|GO:0055114 TON_0429 4bd06881f4eec12adb201d233bbdac80 362 Gene3D G3DSA:3.40.50.720 2 349 5.8E-132 T 23-10-2018 TON_0703 29cc4afe3356d32a07703ad5245f60e2 268 SUPERFAMILY SSF51735 12 263 2.4E-50 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TON_0703 29cc4afe3356d32a07703ad5245f60e2 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 5.4E-15 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TON_0703 29cc4afe3356d32a07703ad5245f60e2 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 150 5.4E-15 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TON_0703 29cc4afe3356d32a07703ad5245f60e2 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 5.4E-15 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TON_0703 29cc4afe3356d32a07703ad5245f60e2 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 5.4E-15 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TON_0703 29cc4afe3356d32a07703ad5245f60e2 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 5.4E-15 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TON_0703 29cc4afe3356d32a07703ad5245f60e2 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 226 246 5.4E-15 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TON_0703 29cc4afe3356d32a07703ad5245f60e2 268 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 262 1.1E-30 T 23-10-2018 TON_0703 29cc4afe3356d32a07703ad5245f60e2 268 Gene3D G3DSA:3.40.50.720 1 265 2.0E-48 T 23-10-2018 TON_0936 f4d4bbb951025e1754692e6787d20046 377 Gene3D G3DSA:3.40.50.1970 1 183 8.7E-43 T 23-10-2018 TON_0936 f4d4bbb951025e1754692e6787d20046 377 SUPERFAMILY SSF56796 2 376 2.09E-97 T 23-10-2018 TON_0936 f4d4bbb951025e1754692e6787d20046 377 Pfam PF00465 Iron-containing alcohol dehydrogenase 6 366 3.8E-96 T 23-10-2018 IPR001670 Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 TON_0936 f4d4bbb951025e1754692e6787d20046 377 Gene3D G3DSA:1.20.1090.10 185 377 2.4E-53 T 23-10-2018 TON_0756 c927116a2ffaf6951fe0d2b45bdd296f 354 SMART SM00471 46 157 1.1E-12 T 23-10-2018 IPR003607 HD/PDEase domain TON_0756 c927116a2ffaf6951fe0d2b45bdd296f 354 Gene3D G3DSA:1.10.3210.10 1 259 1.7E-76 T 23-10-2018 TON_0756 c927116a2ffaf6951fe0d2b45bdd296f 354 Pfam PF01966 HD domain 50 148 1.8E-10 T 23-10-2018 IPR006674 HD domain TON_0756 c927116a2ffaf6951fe0d2b45bdd296f 354 SUPERFAMILY SSF109604 2 352 4.25E-83 T 23-10-2018 TON_0838 5a5e184958f8a26dbf8356abeae0fd7e 204 Gene3D G3DSA:3.40.50.150 8 204 1.6E-41 T 23-10-2018 TON_0838 5a5e184958f8a26dbf8356abeae0fd7e 204 Pfam PF08241 Methyltransferase domain 46 141 1.0E-24 T 23-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 TON_0838 5a5e184958f8a26dbf8356abeae0fd7e 204 SUPERFAMILY SSF53335 9 199 2.79E-41 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TON_1973 03e3a18bb696fbb4ca5c05cb100d626a 277 Pfam PF07722 Peptidase C26 3 219 4.9E-54 T 23-10-2018 IPR011697 Peptidase C26 GO:0016787 Reactome: R-HSA-6798695 TON_1973 03e3a18bb696fbb4ca5c05cb100d626a 277 Gene3D G3DSA:3.40.50.880 1 248 4.8E-66 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like TON_1973 03e3a18bb696fbb4ca5c05cb100d626a 277 SUPERFAMILY SSF52317 3 241 4.2E-32 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like TON_0534 6165ca0cee77eb2105b6fe5fb399b31b 429 Gene3D G3DSA:1.10.645.10 6 425 4.5E-104 T 23-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_0534 6165ca0cee77eb2105b6fe5fb399b31b 429 Pfam PF00374 Nickel-dependent hydrogenase 43 128 1.6E-12 T 23-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 TON_0534 6165ca0cee77eb2105b6fe5fb399b31b 429 Pfam PF00374 Nickel-dependent hydrogenase 325 425 2.7E-9 T 23-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 TON_0534 6165ca0cee77eb2105b6fe5fb399b31b 429 ProSitePatterns PS00508 Nickel-dependent hydrogenases large subunit signature 2. 416 425 - T 23-10-2018 IPR018194 Nickel-dependent hydrogenase, large subunit, nickel binding site GO:0008901|GO:0016151|GO:0055114 TON_0534 6165ca0cee77eb2105b6fe5fb399b31b 429 SUPERFAMILY SSF56762 8 425 7.59E-94 T 23-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_0475 db43dd7e731755326a75a9e35dc7edf5 128 SMART SM00530 20 77 1.5E-5 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TON_0475 db43dd7e731755326a75a9e35dc7edf5 128 Pfam PF01022 Bacterial regulatory protein, arsR family 17 51 3.7E-6 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TON_0475 db43dd7e731755326a75a9e35dc7edf5 128 SUPERFAMILY SSF47413 14 53 6.47E-7 T 23-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TON_0475 db43dd7e731755326a75a9e35dc7edf5 128 Gene3D G3DSA:1.10.260.40 9 62 1.4E-7 T 23-10-2018 TON_1942 a710bb38e5e4e84090d7b68c008ba026 256 Gene3D G3DSA:1.10.3210.10 13 200 6.4E-8 T 23-10-2018 TON_1942 a710bb38e5e4e84090d7b68c008ba026 256 SUPERFAMILY SSF109604 47 170 2.61E-8 T 23-10-2018 TON_1942 a710bb38e5e4e84090d7b68c008ba026 256 SMART SM00471 48 181 0.0095 T 23-10-2018 IPR003607 HD/PDEase domain TON_0277 c9c68cbfceeddafe1adbdc9f5a677659 300 ProSitePatterns PS00668 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. 187 200 - T 23-10-2018 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_0277 c9c68cbfceeddafe1adbdc9f5a677659 300 Pfam PF00146 NADH dehydrogenase 8 295 4.1E-42 T 23-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_1756 47f2eb1b65b4d139950904f5cc272e46 257 Gene3D G3DSA:1.10.287.950 2 249 6.8E-37 T 23-10-2018 TON_1756 47f2eb1b65b4d139950904f5cc272e46 257 SMART SM00283 4 256 3.5E-5 T 23-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TON_1756 47f2eb1b65b4d139950904f5cc272e46 257 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 99 126 7.9E-19 T 23-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TON_1756 47f2eb1b65b4d139950904f5cc272e46 257 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 175 204 7.9E-19 T 23-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TON_1756 47f2eb1b65b4d139950904f5cc272e46 257 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 128 157 7.9E-19 T 23-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 TON_1756 47f2eb1b65b4d139950904f5cc272e46 257 SUPERFAMILY SSF58104 18 238 1.31E-38 T 23-10-2018 TON_1756 47f2eb1b65b4d139950904f5cc272e46 257 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 82 205 1.5E-29 T 23-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 TON_1211 f4dcfac1f5bd9380179462a049f4fdc8 189 Gene3D G3DSA:3.50.30.50 1 189 1.7E-55 T 23-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 TON_1211 f4dcfac1f5bd9380179462a049f4fdc8 189 SUPERFAMILY SSF102198 2 187 2.62E-52 T 23-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 TON_1211 f4dcfac1f5bd9380179462a049f4fdc8 189 Pfam PF04199 Putative cyclase 3 134 5.3E-22 T 23-10-2018 IPR007325 Kynurenine formamidase/cyclase-like GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 TON_0854 399b19f298b5981f7ee077c15943eff7 324 Gene3D G3DSA:3.30.310.10 239 323 3.0E-6 T 23-10-2018 IPR012295 TBP domain superfamily TON_0854 399b19f298b5981f7ee077c15943eff7 324 Pfam PF00899 ThiF family 9 229 1.0E-46 T 23-10-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 TON_0854 399b19f298b5981f7ee077c15943eff7 324 SUPERFAMILY SSF69572 8 313 2.49E-65 T 23-10-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 TON_0854 399b19f298b5981f7ee077c15943eff7 324 Pfam PF00352 Transcription factor TFIID (or TATA-binding protein, TBP) 261 321 1.1E-5 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 TON_0854 399b19f298b5981f7ee077c15943eff7 324 Gene3D G3DSA:3.40.50.720 5 237 1.0E-59 T 23-10-2018 TON_0839 d07a20165baf80284321544574048a83 77 Pfam PF09851 Short C-terminal domain 49 75 3.4E-11 T 23-10-2018 IPR018649 SHOCT domain TON_1771 363456cf98ecf6b347368ceb6ef2a88a 289 SUPERFAMILY SSF103481 38 140 1.7E-14 T 23-10-2018 TON_1771 363456cf98ecf6b347368ceb6ef2a88a 289 SUPERFAMILY SSF103481 180 276 3.53E-17 T 23-10-2018 TON_1771 363456cf98ecf6b347368ceb6ef2a88a 289 Gene3D G3DSA:1.10.3730.20 195 280 2.6E-5 T 23-10-2018 TON_1771 363456cf98ecf6b347368ceb6ef2a88a 289 Pfam PF00892 EamA-like transporter family 3 136 3.5E-24 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TON_1771 363456cf98ecf6b347368ceb6ef2a88a 289 Pfam PF00892 EamA-like transporter family 145 272 1.5E-26 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TON_0715 8daa30637a7fdd740636f2f8db2b4b4c 148 Pfam PF13636 RNA-binding PUA-like domain of methyltransferase RsmF 97 144 2.8E-16 T 23-10-2018 IPR027391 rRNA small subunit methyltransferase F, RNA-binding PUA-like domain TON_0715 8daa30637a7fdd740636f2f8db2b4b4c 148 Gene3D G3DSA:2.30.130.90 47 147 4.5E-9 T 23-10-2018 TON_0224 1c58f6ef96ae526a1787c1248d2176d0 374 SUPERFAMILY SSF53649 2 358 9.01E-75 T 23-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 TON_0224 1c58f6ef96ae526a1787c1248d2176d0 374 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 5 321 4.3E-49 T 23-10-2018 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 TON_0224 1c58f6ef96ae526a1787c1248d2176d0 374 Gene3D G3DSA:3.40.720.10 1 371 5.2E-56 T 23-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 TON_1325 ed2776b271439c23a767b9a73bb84990 135 Gene3D G3DSA:3.30.70.260 47 131 6.5E-10 T 23-10-2018 TON_1325 ed2776b271439c23a767b9a73bb84990 135 Pfam PF01842 ACT domain 59 117 1.1E-10 T 23-10-2018 IPR002912 ACT domain TON_1325 ed2776b271439c23a767b9a73bb84990 135 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 59 106 0.005 T 23-10-2018 TON_1325 ed2776b271439c23a767b9a73bb84990 135 SUPERFAMILY SSF55021 57 129 2.87E-11 T 23-10-2018 TON_0675 636d877c5d39530f1f35054bfc5ea375 385 Gene3D G3DSA:3.40.1280.30 105 247 2.2E-8 T 23-10-2018 IPR038459 tRNA methyltransferase TRM10-type domain superfamily TON_0675 636d877c5d39530f1f35054bfc5ea375 385 Pfam PF04252 Predicted SAM-dependent RNA methyltransferase 174 230 6.9E-5 T 23-10-2018 IPR007364 RNA methyltransferase TK0422/Sfm1 GO:0008168 TON_0675 636d877c5d39530f1f35054bfc5ea375 385 PIRSF PIRSF018978 16 385 2.1E-177 T 23-10-2018 IPR016742 tRNA methyltransferase, archaea GO:0008175|GO:0030488 TON_0864 6db706eabdeb4095c8365c3ff69dcce0 179 Gene3D G3DSA:1.20.1260.10 5 148 1.2E-23 T 23-10-2018 IPR012347 Ferritin-like TON_0864 6db706eabdeb4095c8365c3ff69dcce0 179 SUPERFAMILY SSF47240 8 148 3.88E-18 T 23-10-2018 IPR009078 Ferritin-like superfamily TON_0864 6db706eabdeb4095c8365c3ff69dcce0 179 Pfam PF02915 Rubrerythrin 15 141 2.4E-16 T 23-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 TON_0564 ded31e4b0c3a6ed9cce96395ab032e1b 216 Gene3D G3DSA:3.60.21.10 1 214 4.1E-42 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like TON_0564 ded31e4b0c3a6ed9cce96395ab032e1b 216 Pfam PF00149 Calcineurin-like phosphoesterase 1 175 5.6E-21 T 23-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 TON_0564 ded31e4b0c3a6ed9cce96395ab032e1b 216 SUPERFAMILY SSF56300 1 207 1.26E-73 T 23-10-2018 TON_1390 5e5ee8b4b02b6df010408df0d0e0bd49 315 SMART SM00729 26 238 1.6E-17 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TON_1390 5e5ee8b4b02b6df010408df0d0e0bd49 315 Gene3D G3DSA:3.20.20.70 17 244 1.9E-24 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TON_1390 5e5ee8b4b02b6df010408df0d0e0bd49 315 SUPERFAMILY SSF102114 15 240 2.62E-38 T 23-10-2018 TON_1390 5e5ee8b4b02b6df010408df0d0e0bd49 315 Pfam PF04055 Radical SAM superfamily 36 194 5.4E-12 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TON_0082 af38a810b4a19ea58d5cf11e3c301934 184 TIGRFAM TIGR03653 uL6_arch: ribosomal protein uL6 8 177 7.6E-80 T 23-10-2018 IPR019907 Ribosomal protein L6P, archaea GO:0003735|GO:0005840|GO:0006412|GO:0019843 TON_0082 af38a810b4a19ea58d5cf11e3c301934 184 ProSitePatterns PS00700 Ribosomal protein L6 signature 2. 156 177 - T 23-10-2018 IPR002359 Ribosomal protein L6, conserved site-2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0082 af38a810b4a19ea58d5cf11e3c301934 184 Gene3D G3DSA:3.90.930.12 86 182 2.7E-38 T 23-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0082 af38a810b4a19ea58d5cf11e3c301934 184 SUPERFAMILY SSF56053 86 177 4.1E-31 T 23-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0082 af38a810b4a19ea58d5cf11e3c301934 184 PIRSF PIRSF002162 5 182 4.4E-41 T 23-10-2018 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0082 af38a810b4a19ea58d5cf11e3c301934 184 SUPERFAMILY SSF56053 8 85 3.4E-22 T 23-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0082 af38a810b4a19ea58d5cf11e3c301934 184 Pfam PF00347 Ribosomal protein L6 13 85 1.7E-17 T 23-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0082 af38a810b4a19ea58d5cf11e3c301934 184 Pfam PF00347 Ribosomal protein L6 97 171 1.3E-15 T 23-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0082 af38a810b4a19ea58d5cf11e3c301934 184 Hamap MF_01365_A 50S ribosomal protein L6 [rplF]. 2 178 39.351 T 23-10-2018 IPR019907 Ribosomal protein L6P, archaea GO:0003735|GO:0005840|GO:0006412|GO:0019843 TON_0082 af38a810b4a19ea58d5cf11e3c301934 184 Gene3D G3DSA:3.90.930.12 6 85 1.4E-30 T 23-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0655 c01c9813c2d65e76c4b11c523b6d9480 132 Pfam PF09685 Domain of unknown function (DUF4870) 32 118 2.2E-11 T 23-10-2018 IPR019109 Protein of unknown function DUF4870 TON_0150 defab4f02895d48afa034462f8becf90 138 Pfam PF01402 Ribbon-helix-helix protein, copG family 5 42 4.4E-8 T 23-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 TON_0150 defab4f02895d48afa034462f8becf90 138 SUPERFAMILY SSF55021 53 133 3.43E-29 T 23-10-2018 TON_0150 defab4f02895d48afa034462f8becf90 138 Hamap MF_00476 Nickel-responsive regulator [nikR]. 3 133 31.0 T 23-10-2018 IPR022988 Nickel-responsive transcriptional regulator NikR GO:0003677|GO:0006355|GO:0010045|GO:0016151 TON_0150 defab4f02895d48afa034462f8becf90 138 Gene3D G3DSA:1.10.1220.10 10 50 5.1E-22 T 23-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 TON_0150 defab4f02895d48afa034462f8becf90 138 SUPERFAMILY SSF47598 2 49 4.89E-14 T 23-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 TON_0150 defab4f02895d48afa034462f8becf90 138 Pfam PF08753 NikR C terminal nickel binding domain 55 131 6.6E-34 T 23-10-2018 IPR014864 Transcription factor, NikR, nickel binding C-terminal TON_0150 defab4f02895d48afa034462f8becf90 138 Gene3D G3DSA:3.30.70.1150 51 138 9.5E-38 T 23-10-2018 IPR027271 Acetolactate synthase/Transcription factor NikR, C-terminal TON_1969 23bb6591fa8d53eaae3e06784ea8a8dc 125 SUPERFAMILY SSF101744 38 124 2.96E-24 T 23-10-2018 IPR023534 Rof/RNase P-like Reactome: R-HSA-6784531 TON_1969 23bb6591fa8d53eaae3e06784ea8a8dc 125 Hamap MF_00754 Ribonuclease P protein component 1 [rnp1]. 45 120 19.53 T 23-10-2018 IPR023538 Ribonuclease P protein component 1 GO:0001682|GO:0004526 TON_1969 23bb6591fa8d53eaae3e06784ea8a8dc 125 Pfam PF01868 Domain of unknown function UPF0086 42 121 2.0E-19 T 23-10-2018 IPR002730 Ribonuclease P/MRP, subunit p29 GO:0003723|GO:0004540|GO:0006396|GO:0030677 Reactome: R-HSA-6784531 TON_1969 23bb6591fa8d53eaae3e06784ea8a8dc 125 SMART SM00538 37 125 2.4E-32 T 23-10-2018 IPR002730 Ribonuclease P/MRP, subunit p29 GO:0003723|GO:0004540|GO:0006396|GO:0030677 Reactome: R-HSA-6784531 TON_1969 23bb6591fa8d53eaae3e06784ea8a8dc 125 Gene3D G3DSA:2.30.30.210 17 125 6.2E-38 T 23-10-2018 IPR036980 Ribonuclease P/MRP, subunit p29 superfamily GO:0003723|GO:0004540|GO:0008033|GO:0030677 Reactome: R-HSA-6784531 TON_0807 12e8c64962b3fb0d33747ee32a19bcd3 485 ProSitePatterns PS00217 Sugar transport proteins signature 2. 172 197 - T 23-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 TON_0807 12e8c64962b3fb0d33747ee32a19bcd3 485 Pfam PF00083 Sugar (and other) transporter 111 484 1.0E-45 T 23-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 TON_0807 12e8c64962b3fb0d33747ee32a19bcd3 485 Gene3D G3DSA:1.10.286.90 252 284 1.1E-6 T 23-10-2018 TON_0807 12e8c64962b3fb0d33747ee32a19bcd3 485 ProSitePatterns PS00216 Sugar transport proteins signature 1. 353 368 - T 23-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 TON_0807 12e8c64962b3fb0d33747ee32a19bcd3 485 SUPERFAMILY SSF103473 62 483 1.44E-79 T 23-10-2018 IPR036259 MFS transporter superfamily TON_1960 a6c71f9839dc47e6a033b02584a31799 350 SUPERFAMILY SSF56266 2 345 3.4E-101 T 23-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 TON_1960 a6c71f9839dc47e6a033b02584a31799 350 Gene3D G3DSA:3.60.70.12 1 347 1.7E-137 T 23-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 TON_1960 a6c71f9839dc47e6a033b02584a31799 350 Pfam PF03576 Peptidase family S58 19 326 1.5E-110 T 23-10-2018 IPR005321 Peptidase S58, DmpA TON_1532 1275b736ee38faa126dbdd49ce8cffa3 249 Gene3D G3DSA:3.30.930.10 8 249 1.8E-62 T 23-10-2018 TON_1532 1275b736ee38faa126dbdd49ce8cffa3 249 Pfam PF03099 Biotin/lipoate A/B protein ligase family 63 157 4.5E-12 T 23-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 TON_1532 1275b736ee38faa126dbdd49ce8cffa3 249 SUPERFAMILY SSF55681 1 246 2.8E-69 T 23-10-2018 TON_0470 e41341dffed772d64171290fde672b94 205 TIGRFAM TIGR04288 CGP_CTERM: CGP-CTERM domain 184 203 1.3E-4 T 23-10-2018 IPR027552 CGP-CTERM domain TON_0470 e41341dffed772d64171290fde672b94 205 Gene3D G3DSA:3.40.30.10 13 119 3.4E-9 T 23-10-2018 TON_0470 e41341dffed772d64171290fde672b94 205 SUPERFAMILY SSF52833 18 108 9.39E-13 T 23-10-2018 IPR036249 Thioredoxin-like superfamily TON_0470 e41341dffed772d64171290fde672b94 205 Pfam PF00462 Glutaredoxin 35 92 9.9E-5 T 23-10-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 TON_0541 6b928254174d0a492fa454c296a4826f 125 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 7 18 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TON_0541 6b928254174d0a492fa454c296a4826f 125 Pfam PF12838 4Fe-4S dicluster domain 7 54 6.3E-10 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TON_0541 6b928254174d0a492fa454c296a4826f 125 SUPERFAMILY SSF54862 4 76 1.36E-14 T 23-10-2018 TON_0541 6b928254174d0a492fa454c296a4826f 125 Gene3D G3DSA:3.30.70.20 2 57 6.9E-12 T 23-10-2018 TON_1188 1c908312af2305134a458315431ff7ca 343 TIGRFAM TIGR02537 arch_flag_Nterm: archaeal flagellin N-terminal-like domain 5 28 1.7E-5 T 23-10-2018 IPR013373 Flagellin/pilin, N-terminal TON_1188 1c908312af2305134a458315431ff7ca 343 Pfam PF01917 Archaebacterial flagellin 218 329 7.1E-9 T 23-10-2018 IPR002774 Flagellin, archaea GO:0005198|GO:0006928 TON_1188 1c908312af2305134a458315431ff7ca 343 Pfam PF01917 Archaebacterial flagellin 7 215 8.4E-34 T 23-10-2018 IPR002774 Flagellin, archaea GO:0005198|GO:0006928 TON_1805 a3a0dd9cd9aae4ce35a7907f7fd1020f 276 Pfam PF00892 EamA-like transporter family 139 269 4.5E-19 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TON_1805 a3a0dd9cd9aae4ce35a7907f7fd1020f 276 Pfam PF00892 EamA-like transporter family 5 131 5.4E-21 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TON_1805 a3a0dd9cd9aae4ce35a7907f7fd1020f 276 SUPERFAMILY SSF103481 176 269 6.54E-14 T 23-10-2018 TON_1805 a3a0dd9cd9aae4ce35a7907f7fd1020f 276 SUPERFAMILY SSF103481 38 133 3.66E-12 T 23-10-2018 TON_1257 09945547c3e05c3dd6da16025304266d 63 Gene3D G3DSA:1.10.1220.10 11 46 4.8E-10 T 23-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 TON_1257 09945547c3e05c3dd6da16025304266d 63 Pfam PF01402 Ribbon-helix-helix protein, copG family 7 45 5.7E-9 T 23-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 TON_1257 09945547c3e05c3dd6da16025304266d 63 SUPERFAMILY SSF47598 3 46 1.95E-12 T 23-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 TON_1176 66d78eb0a2152746103980cd8a108a14 220 TIGRFAM TIGR00080 pimt: protein-L-isoaspartate O-methyltransferase 12 216 1.4E-61 T 23-10-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 TON_1176 66d78eb0a2152746103980cd8a108a14 220 Gene3D G3DSA:3.40.50.150 3 220 4.1E-93 T 23-10-2018 TON_1176 66d78eb0a2152746103980cd8a108a14 220 SUPERFAMILY SSF53335 3 215 2.32E-54 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TON_1176 66d78eb0a2152746103980cd8a108a14 220 ProSitePatterns PS01279 Protein-L-isoaspartate(D-aspartate) O-methyltransferase signature. 137 152 - T 23-10-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 TON_1176 66d78eb0a2152746103980cd8a108a14 220 Hamap MF_00090 Protein-L-isoaspartate O-methyltransferase [pcm]. 3 218 40.831 T 23-10-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 TON_1176 66d78eb0a2152746103980cd8a108a14 220 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 13 215 1.4E-67 T 23-10-2018 TON_0830 4a8a6b55351aa61d39717c47ee98be10 234 Pfam PF12698 ABC-2 family transporter protein 51 228 2.0E-9 T 23-10-2018 TON_0878 045a798a7f808063c98a36f4a12d8d33 295 Pfam PF13393 Histidyl-tRNA synthetase 190 256 3.1E-9 T 23-10-2018 TON_0878 045a798a7f808063c98a36f4a12d8d33 295 Pfam PF13393 Histidyl-tRNA synthetase 5 180 2.4E-18 T 23-10-2018 TON_0878 045a798a7f808063c98a36f4a12d8d33 295 Gene3D G3DSA:3.30.930.10 10 256 1.3E-38 T 23-10-2018 TON_0878 045a798a7f808063c98a36f4a12d8d33 295 SUPERFAMILY SSF55681 12 254 2.88E-34 T 23-10-2018 TON_1533 a551f489417fc943eb0f6bb066d14bce 158 Pfam PF00717 Peptidase S24-like 39 91 6.4E-8 T 23-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C TON_1533 a551f489417fc943eb0f6bb066d14bce 158 TIGRFAM TIGR02228 sigpep_I_arch: signal peptidase I 5 151 7.7E-36 T 23-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 TON_1533 a551f489417fc943eb0f6bb066d14bce 158 PRINTS PR00728 Eukaryotic signal peptidase (S26B) family signature 39 54 1.5E-8 T 23-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 TON_1533 a551f489417fc943eb0f6bb066d14bce 158 PRINTS PR00728 Eukaryotic signal peptidase (S26B) family signature 104 115 1.5E-8 T 23-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 TON_1533 a551f489417fc943eb0f6bb066d14bce 158 SUPERFAMILY SSF51306 36 89 8.89E-11 T 23-10-2018 IPR036286 LexA/Signal peptidase-like superfamily TON_1664 95d3ea32f8eb6ae8678c132b77a1c2a8 438 Pfam PF03600 Citrate transporter 40 326 1.1E-38 T 23-10-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 TON_1664 95d3ea32f8eb6ae8678c132b77a1c2a8 438 ProSitePatterns PS01271 Sodium:sulfate symporter family signature. 386 402 - T 23-10-2018 IPR031312 Sodium/sulphate symporter, conserved site Reactome: R-HSA-433137 TON_0812 6ecd7d174acf8d1581f101233db8bc85 171 Gene3D G3DSA:3.10.450.40 66 136 4.7E-18 T 23-10-2018 TON_0812 6ecd7d174acf8d1581f101233db8bc85 171 Pfam PF03413 Peptidase propeptide and YPEB domain 75 132 2.9E-14 T 23-10-2018 IPR025711 PepSY domain TON_0766 6b18e2fbf8253619ad061552a32e2dca 259 SMART SM00090 23 257 1.6E-117 T 23-10-2018 IPR000687 RIO kinase GO:0004674|GO:0005524 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6791226 TON_0766 6b18e2fbf8253619ad061552a32e2dca 259 Gene3D G3DSA:1.10.510.10 156 258 1.6E-25 T 23-10-2018 TON_0766 6b18e2fbf8253619ad061552a32e2dca 259 ProSitePatterns PS01245 RIO1/ZK632.3/MJ0444 family signature. 191 202 - T 23-10-2018 IPR018935 RIO kinase, conserved site GO:0004674|GO:0005524 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6791226 TON_0766 6b18e2fbf8253619ad061552a32e2dca 259 ProSitePatterns PS00109 Tyrosine protein kinases specific active-site signature. 191 203 - T 23-10-2018 IPR008266 Tyrosine-protein kinase, active site GO:0004672|GO:0006468 TON_0766 6b18e2fbf8253619ad061552a32e2dca 259 Pfam PF01163 RIO1 family 65 246 1.2E-53 T 23-10-2018 TON_0766 6b18e2fbf8253619ad061552a32e2dca 259 SUPERFAMILY SSF56112 45 228 6.62E-22 T 23-10-2018 IPR011009 Protein kinase-like domain superfamily TON_0766 6b18e2fbf8253619ad061552a32e2dca 259 Gene3D G3DSA:3.30.200.20 51 151 1.1E-12 T 23-10-2018 TON_0915 7eac21825adaec5ae32de917131c4d2b 295 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 100 111 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TON_0915 7eac21825adaec5ae32de917131c4d2b 295 Gene3D G3DSA:3.30.70.20 69 115 3.8E-11 T 23-10-2018 TON_0915 7eac21825adaec5ae32de917131c4d2b 295 SUPERFAMILY SSF52540 2 292 6.64E-37 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_0915 7eac21825adaec5ae32de917131c4d2b 295 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 3 265 2.3E-22 T 23-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain TON_0915 7eac21825adaec5ae32de917131c4d2b 295 Pfam PF14697 4Fe-4S dicluster domain 64 117 1.6E-10 T 23-10-2018 TON_0915 7eac21825adaec5ae32de917131c4d2b 295 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 71 82 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TON_0915 7eac21825adaec5ae32de917131c4d2b 295 SUPERFAMILY SSF54862 54 121 5.23E-17 T 23-10-2018 TON_0059 acae5bed834454b98ceb4125f1c123d1 197 SUPERFAMILY SSF52540 9 174 1.52E-14 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_0059 acae5bed834454b98ceb4125f1c123d1 197 Gene3D G3DSA:3.40.50.300 5 197 1.5E-18 T 23-10-2018 TON_0059 acae5bed834454b98ceb4125f1c123d1 197 SMART SM00382 31 171 2.0E-5 T 23-10-2018 IPR003593 AAA+ ATPase domain TON_0059 acae5bed834454b98ceb4125f1c123d1 197 Pfam PF00437 Type II/IV secretion system protein 7 112 1.3E-10 T 23-10-2018 IPR001482 Type II/IV secretion system protein TON_0142 efb6c7914b41fcd8a533595cfe291df4 696 Pfam PF11977 Zc3h12a-like Ribonuclease NYN domain 560 684 3.5E-20 T 23-10-2018 IPR021869 Ribonuclease Zc3h12a-like, NYN domain TON_0142 efb6c7914b41fcd8a533595cfe291df4 696 Gene3D G3DSA:3.40.50.11980 559 693 5.1E-25 T 23-10-2018 TON_1742 9e7ec466fbd89029fd959888e9b41b28 141 Pfam PF02675 S-adenosylmethionine decarboxylase 7 113 1.8E-37 T 23-10-2018 IPR003826 S-adenosylmethionine decarboxylase family, prokaryotic GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 TON_1742 9e7ec466fbd89029fd959888e9b41b28 141 Hamap MF_00464 S-adenosylmethionine decarboxylase proenzyme [speH]. 1 117 31.298 T 23-10-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 TON_1742 9e7ec466fbd89029fd959888e9b41b28 141 Gene3D G3DSA:3.30.360.110 1 62 2.6E-19 T 23-10-2018 TON_1742 9e7ec466fbd89029fd959888e9b41b28 141 TIGRFAM TIGR03330 SAM_DCase_Bsu: S-adenosylmethionine decarboxylase proenzyme 3 113 1.1E-43 T 23-10-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 TON_1742 9e7ec466fbd89029fd959888e9b41b28 141 Gene3D G3DSA:3.30.160.750 63 126 3.0E-24 T 23-10-2018 TON_1742 9e7ec466fbd89029fd959888e9b41b28 141 SUPERFAMILY SSF56276 3 117 5.36E-42 T 23-10-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 TON_0228 9d07fdf8fd5c7bdf066ccbd3c9da8468 67 SUPERFAMILY SSF54285 4 67 4.36E-13 T 23-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp TON_0228 9d07fdf8fd5c7bdf066ccbd3c9da8468 67 Gene3D G3DSA:3.10.20.30 1 67 7.3E-26 T 23-10-2018 IPR012675 Beta-grasp domain superfamily TON_0228 9d07fdf8fd5c7bdf066ccbd3c9da8468 67 Pfam PF02597 ThiS family 10 67 7.3E-11 T 23-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 TON_1225 038786b2667e998ac04cb0a6177e9441 215 Pfam PF01863 Protein of unknown function DUF45 11 197 6.9E-48 T 23-10-2018 IPR002725 Protein of unknown function DUF45 TON_1225 038786b2667e998ac04cb0a6177e9441 215 Gene3D G3DSA:3.30.2010.10 106 202 9.9E-19 T 23-10-2018 TON_0895 56926a54196744ce6ede9d44104e2fd1 290 TIGRFAM TIGR02582 cas7_TM1809: CRISPR type III-A/MTUBE-associated RAMP protein Csm3 121 238 5.1E-40 T 23-10-2018 IPR013412 CRISPR-associated RAMP Csm3 TON_0895 56926a54196744ce6ede9d44104e2fd1 290 TIGRFAM TIGR02582 cas7_TM1809: CRISPR type III-A/MTUBE-associated RAMP protein Csm3 7 68 1.7E-24 T 23-10-2018 IPR013412 CRISPR-associated RAMP Csm3 TON_0895 56926a54196744ce6ede9d44104e2fd1 290 Pfam PF03787 RAMP superfamily 14 237 2.9E-23 T 23-10-2018 IPR005537 CRISPR type III-associated RAMP protein TON_0646 5723ceaf69d752d1c369181ded15dca6 455 PIRSF PIRSF006603 5 455 1.3E-109 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 TON_0646 5723ceaf69d752d1c369181ded15dca6 455 Pfam PF01554 MatE 240 406 4.7E-35 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 TON_0646 5723ceaf69d752d1c369181ded15dca6 455 Pfam PF01554 MatE 16 176 1.2E-38 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 TON_0646 5723ceaf69d752d1c369181ded15dca6 455 TIGRFAM TIGR00797 matE: MATE efflux family protein 16 417 5.3E-128 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 TON_1374 df16e87d77c6844d216481a5b0ef377b 261 PIRSF PIRSF004853 1 253 2.8E-113 T 23-10-2018 IPR002855 Phosphopantoate/pantothenate synthetase TON_1374 df16e87d77c6844d216481a5b0ef377b 261 Pfam PF02006 Phosphopantothenate/pantothenate synthetase 66 241 1.5E-74 T 23-10-2018 IPR002855 Phosphopantoate/pantothenate synthetase TON_1374 df16e87d77c6844d216481a5b0ef377b 261 ProDom PD016827 ARCHAEA ST0532 APE1937 VNG0250C MM2281 PAE3406 AF0927 UNCHARACTERIZED C3_0043 MJ0209 67 251 3.0E-93 T 23-10-2018 IPR002855 Phosphopantoate/pantothenate synthetase TON_1374 df16e87d77c6844d216481a5b0ef377b 261 Gene3D G3DSA:3.40.50.12640 1 261 6.9E-122 T 23-10-2018 IPR038138 Phosphopantoate/pantothenate synthetase superfamily TON_0484 7643f05cbfab403629a8493d85c00410 433 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 348 368 - T 23-10-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 TON_0484 7643f05cbfab403629a8493d85c00410 433 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 22 430 4.5E-99 T 23-10-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 TON_0484 7643f05cbfab403629a8493d85c00410 433 Pfam PF00860 Permease family 24 401 2.6E-95 T 23-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 TON_1592 4542d994081ba6694899912f03705045 189 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 105 166 5.0E-21 T 23-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_1592 4542d994081ba6694899912f03705045 189 SUPERFAMILY SSF143243 23 175 9.15E-30 T 23-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_1592 4542d994081ba6694899912f03705045 189 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 51 167 3.0E-21 T 23-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_1592 4542d994081ba6694899912f03705045 189 Gene3D G3DSA:3.30.460.80 19 149 3.3E-17 T 23-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_0669 a34a0444a1d391a1ae03866277c5211b 229 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 81 89 - T 23-10-2018 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 TON_0669 a34a0444a1d391a1ae03866277c5211b 229 Gene3D G3DSA:3.40.50.1860 6 220 1.8E-88 T 23-10-2018 TON_0669 a34a0444a1d391a1ae03866277c5211b 229 Pfam PF01177 Asp/Glu/Hydantoin racemase 9 222 2.5E-62 T 23-10-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 TON_0669 a34a0444a1d391a1ae03866277c5211b 229 Gene3D G3DSA:3.40.50.1860 107 214 1.8E-88 T 23-10-2018 TON_0669 a34a0444a1d391a1ae03866277c5211b 229 TIGRFAM TIGR00035 asp_race: aspartate racemase 3 228 1.6E-104 T 23-10-2018 IPR004380 Aspartate racemase GO:0006520|GO:0016855 TON_0669 a34a0444a1d391a1ae03866277c5211b 229 SUPERFAMILY SSF53681 4 117 1.46E-36 T 23-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 TON_0669 a34a0444a1d391a1ae03866277c5211b 229 SUPERFAMILY SSF53681 119 227 9.81E-25 T 23-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 TON_0486 59dc3a5e87ad6c2b367927992a0f5a8b 232 Pfam PF12838 4Fe-4S dicluster domain 59 113 1.1E-10 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TON_0486 59dc3a5e87ad6c2b367927992a0f5a8b 232 SUPERFAMILY SSF54862 22 118 1.35E-21 T 23-10-2018 TON_0486 59dc3a5e87ad6c2b367927992a0f5a8b 232 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 60 71 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TON_0486 59dc3a5e87ad6c2b367927992a0f5a8b 232 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 99 110 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TON_0486 59dc3a5e87ad6c2b367927992a0f5a8b 232 Gene3D G3DSA:3.30.70.3270 38 150 9.1E-22 T 23-10-2018 TON_1608 f1b8735a9cf8b1ccb000c9ec6e71f242 227 Gene3D G3DSA:3.20.20.70 2 225 1.7E-109 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TON_1608 f1b8735a9cf8b1ccb000c9ec6e71f242 227 Hamap MF_00114 Deoxyribose-phosphate aldolase [deoC]. 7 223 40.007 T 23-10-2018 IPR028581 Deoxyribose-phosphate aldolase type I GO:0004139 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180 TON_1608 f1b8735a9cf8b1ccb000c9ec6e71f242 227 Pfam PF01791 DeoC/LacD family aldolase 11 218 7.6E-24 T 23-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 TON_1608 f1b8735a9cf8b1ccb000c9ec6e71f242 227 SMART SM01133 8 221 5.2E-120 T 23-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 TON_1608 f1b8735a9cf8b1ccb000c9ec6e71f242 227 SUPERFAMILY SSF51569 6 222 3.14E-95 T 23-10-2018 TON_1608 f1b8735a9cf8b1ccb000c9ec6e71f242 227 PIRSF PIRSF001357 3 226 2.2E-92 T 23-10-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 TON_1608 f1b8735a9cf8b1ccb000c9ec6e71f242 227 TIGRFAM TIGR00126 deoC: deoxyribose-phosphate aldolase 9 219 2.9E-93 T 23-10-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 TON_0134 5b49e40dc9bfae32426c3177d2746f4d 258 SUPERFAMILY SSF53633 1 257 1.31E-32 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily TON_0134 5b49e40dc9bfae32426c3177d2746f4d 258 PIRSF PIRSF016496 1 258 7.2E-81 T 23-10-2018 IPR024192 Fosfomycin resistance kinase, FomA-type GO:0016301 KEGG: 00900+2.7.4.26|MetaCyc: PWY-6174|MetaCyc: PWY-7524 TON_0134 5b49e40dc9bfae32426c3177d2746f4d 258 Gene3D G3DSA:3.40.1160.10 1 257 3.5E-63 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily TON_0134 5b49e40dc9bfae32426c3177d2746f4d 258 Pfam PF00696 Amino acid kinase family 1 228 3.9E-41 T 23-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 TON_0619 8daa03cd365cc639efe6e2b9b4868e70 381 Pfam PF05559 Protein of unknown function (DUF763) 4 335 1.7E-121 T 23-10-2018 IPR008482 Protein of unknown function DUF763 TON_1166 7f27e7a3bb2f98a78d0de361d5ce4dd7 535 SUPERFAMILY SSF54001 277 457 1.64E-10 T 23-10-2018 IPR038765 Papain-like cysteine peptidase superfamily TON_1166 7f27e7a3bb2f98a78d0de361d5ce4dd7 535 Pfam PF01841 Transglutaminase-like superfamily 291 387 3.3E-8 T 23-10-2018 IPR002931 Transglutaminase-like TON_1166 7f27e7a3bb2f98a78d0de361d5ce4dd7 535 Gene3D G3DSA:3.10.620.30 261 401 6.1E-8 T 23-10-2018 TON_0959 38363cc9a75d9f27b7a08fccf95bfdc8 137 Pfam PF01957 NfeD-like C-terminal, partner-binding 8 136 3.7E-16 T 23-10-2018 IPR002810 NfeD-like, C-terminal domain TON_0959 38363cc9a75d9f27b7a08fccf95bfdc8 137 SUPERFAMILY SSF141322 71 137 7.32E-19 T 23-10-2018 TON_0959 38363cc9a75d9f27b7a08fccf95bfdc8 137 Gene3D G3DSA:2.40.50.140 69 137 5.0E-19 T 23-10-2018 TON_1404 e42845549259fa23ae911374f0a4a859 234 Pfam PF07758 Protein of unknown function (DUF1614) 56 233 7.3E-58 T 23-10-2018 IPR011672 Protein of unknown function DUF1614 TON_0800 3caeb10da8475b25a063e0851be7ce66 240 Gene3D G3DSA:3.40.50.300 6 239 2.7E-38 T 23-10-2018 TON_0800 3caeb10da8475b25a063e0851be7ce66 240 SUPERFAMILY SSF52540 7 228 2.04E-39 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_0800 3caeb10da8475b25a063e0851be7ce66 240 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 11 215 6.5E-11 T 23-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain TON_0994 34226891a828852786f9e9de13cd707c 149 SUPERFAMILY SSF46785 6 89 9.75E-23 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TON_0994 34226891a828852786f9e9de13cd707c 149 Pfam PF03551 Transcriptional regulator PadR-like family 14 82 5.6E-16 T 23-10-2018 IPR005149 Transcription regulator PadR, N-terminal TON_0994 34226891a828852786f9e9de13cd707c 149 Gene3D G3DSA:1.10.10.10 1 101 3.4E-25 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TON_1640 aa21754297a1e52dad122fc530c5e2e1 226 Hamap MF_00147_A Triosephosphate isomerase [tpiA]. 6 225 44.133 T 23-10-2018 IPR022891 Triosephosphate isomerase, archaeal GO:0004807|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003 TON_1640 aa21754297a1e52dad122fc530c5e2e1 226 Pfam PF00121 Triosephosphate isomerase 8 114 2.2E-10 T 23-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TON_1640 aa21754297a1e52dad122fc530c5e2e1 226 Gene3D G3DSA:3.20.20.70 1 225 3.0E-95 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TON_1640 aa21754297a1e52dad122fc530c5e2e1 226 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 8 212 3.4E-63 T 23-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TON_1640 aa21754297a1e52dad122fc530c5e2e1 226 ProSitePatterns PS00171 Triosephosphate isomerase active site. 142 152 - T 23-10-2018 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TON_1640 aa21754297a1e52dad122fc530c5e2e1 226 Pfam PF05690 Thiazole biosynthesis protein ThiG 170 216 1.1E-5 T 23-10-2018 IPR033983 Thiazole synthase ThiG KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 TON_1640 aa21754297a1e52dad122fc530c5e2e1 226 SUPERFAMILY SSF51351 3 221 9.82E-47 T 23-10-2018 IPR035990 Triosephosphate isomerase superfamily GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TON_0114 17ef4f6cea466e97adcd78f0e0bcae26 108 Gene3D G3DSA:1.10.10.10 2 107 4.7E-26 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TON_0114 17ef4f6cea466e97adcd78f0e0bcae26 108 SUPERFAMILY SSF46785 3 105 2.27E-23 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TON_0114 17ef4f6cea466e97adcd78f0e0bcae26 108 Pfam PF03551 Transcriptional regulator PadR-like family 21 94 7.1E-19 T 23-10-2018 IPR005149 Transcription regulator PadR, N-terminal TON_0264 427ee22a2f813bd7a749da7aedddac50 193 Pfam PF12804 MobA-like NTP transferase domain 3 157 7.0E-32 T 23-10-2018 IPR025877 MobA-like NTP transferase TON_0264 427ee22a2f813bd7a749da7aedddac50 193 Hamap MF_00316 Molybdenum cofactor guanylyltransferase [mobA]. 1 188 20.717 T 23-10-2018 IPR013482 Molybdenum cofactor guanylyltransferase GO:0003824|GO:0006777 KEGG: 00790+2.7.7.77|MetaCyc: PWY-5964|MetaCyc: PWY-7639 TON_0264 427ee22a2f813bd7a749da7aedddac50 193 SUPERFAMILY SSF53448 1 185 1.08E-29 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TON_0264 427ee22a2f813bd7a749da7aedddac50 193 Gene3D G3DSA:3.90.550.10 4 192 9.0E-47 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TON_0616 6035c58ce3391132104628a6f9e02bc7 305 Pfam PF01384 Phosphate transporter family 14 296 5.0E-50 T 23-10-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 TON_1921 433ea862e1dde527cf0e39ab5a33c063 216 Pfam PF00149 Calcineurin-like phosphoesterase 20 129 1.2E-8 T 23-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 TON_1921 433ea862e1dde527cf0e39ab5a33c063 216 Gene3D G3DSA:3.60.21.10 11 139 2.3E-10 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like TON_1921 433ea862e1dde527cf0e39ab5a33c063 216 PIRSF PIRSF000887 4 215 1.8E-36 T 23-10-2018 IPR024173 Phosphoesterase, MJ0037 TON_1921 433ea862e1dde527cf0e39ab5a33c063 216 SUPERFAMILY SSF56300 20 156 4.43E-15 T 23-10-2018 TON_0466 b5f804db6dd75f3ed206f5e1fed05cea 153 Pfam PF10050 Predicted metal-binding protein (DUF2284) 8 138 1.3E-34 T 23-10-2018 IPR019271 Protein of unknown function DUF2284, metal-binding TON_0466 b5f804db6dd75f3ed206f5e1fed05cea 153 PIRSF PIRSF018748 1 153 8.9E-58 T 23-10-2018 IPR019271 Protein of unknown function DUF2284, metal-binding TON_0469 a43a269df75307d2421f4dabc78beed4 154 Gene3D G3DSA:1.25.40.10 51 153 4.6E-21 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TON_0469 a43a269df75307d2421f4dabc78beed4 154 Gene3D G3DSA:1.25.40.10 2 50 3.1E-8 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TON_0469 a43a269df75307d2421f4dabc78beed4 154 SUPERFAMILY SSF48452 22 144 6.72E-8 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TON_0872 051aa6ead7b97558d60a97b41054d9fb 104 SUPERFAMILY SSF47240 18 89 1.98E-19 T 23-10-2018 IPR009078 Ferritin-like superfamily TON_0872 051aa6ead7b97558d60a97b41054d9fb 104 Gene3D G3DSA:1.20.1260.10 4 97 1.2E-10 T 23-10-2018 IPR012347 Ferritin-like TON_0872 051aa6ead7b97558d60a97b41054d9fb 104 Pfam PF02915 Rubrerythrin 28 91 1.2E-8 T 23-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 TON_1761 f0c0858cf21079311e26ff966b5c4b25 300 Gene3D G3DSA:3.20.20.70 50 285 2.9E-30 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TON_1761 f0c0858cf21079311e26ff966b5c4b25 300 Pfam PF04055 Radical SAM superfamily 60 209 1.2E-13 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TON_1761 f0c0858cf21079311e26ff966b5c4b25 300 SUPERFAMILY SSF102114 59 261 4.97E-31 T 23-10-2018 TON_1761 f0c0858cf21079311e26ff966b5c4b25 300 SMART SM00729 55 252 3.0E-5 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TON_0945 c33554fb71d28d86ebe42c1dba123958 334 Gene3D G3DSA:3.40.50.720 4 317 2.0E-141 T 23-10-2018 TON_0945 c33554fb71d28d86ebe42c1dba123958 334 Gene3D G3DSA:3.40.50.720 98 290 2.0E-141 T 23-10-2018 TON_0945 c33554fb71d28d86ebe42c1dba123958 334 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 110 290 8.1E-68 T 23-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 TON_0945 c33554fb71d28d86ebe42c1dba123958 334 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 5 322 4.1E-37 T 23-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 TON_0945 c33554fb71d28d86ebe42c1dba123958 334 SUPERFAMILY SSF51735 103 290 1.76E-66 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TON_0945 c33554fb71d28d86ebe42c1dba123958 334 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 230 246 - T 23-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site TON_0945 c33554fb71d28d86ebe42c1dba123958 334 SUPERFAMILY SSF52283 2 133 4.73E-43 T 23-10-2018 TON_0945 c33554fb71d28d86ebe42c1dba123958 334 Hamap MF_00776 Glyoxylate reductase [gyaR]. 1 331 60.392 T 23-10-2018 IPR023519 Glyoxylate reductase GyaR GO:0047964|GO:0055114 KEGG: 00630+1.1.1.26|MetaCyc: PWY-7294|MetaCyc: PWY-7295 TON_0356 8f5ca1a8b8d619ab1b1b1ae9bac84f9b 358 Gene3D G3DSA:3.40.50.300 162 357 2.0E-58 T 23-10-2018 TON_0356 8f5ca1a8b8d619ab1b1b1ae9bac84f9b 358 Gene3D G3DSA:1.20.120.1190 1 161 3.8E-58 T 23-10-2018 TON_0356 8f5ca1a8b8d619ab1b1b1ae9bac84f9b 358 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 218 233 1.2E-13 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 TON_0356 8f5ca1a8b8d619ab1b1b1ae9bac84f9b 358 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 170 190 1.2E-13 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 TON_0356 8f5ca1a8b8d619ab1b1b1ae9bac84f9b 358 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 191 209 1.2E-13 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 TON_0356 8f5ca1a8b8d619ab1b1b1ae9bac84f9b 358 SUPERFAMILY SSF52540 168 350 8.14E-43 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_0356 8f5ca1a8b8d619ab1b1b1ae9bac84f9b 358 Pfam PF06858 Nucleolar GTP-binding protein 1 (NOG1) 234 291 1.0E-24 T 23-10-2018 IPR010674 Nucleolar GTP-binding protein 1, Rossman-fold domain GO:0005525 TON_0356 8f5ca1a8b8d619ab1b1b1ae9bac84f9b 358 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 169 326 3.4E-17 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 TON_0162 db40a0cac65af3b9f42cbae900bafc44 428 SUPERFAMILY SSF53822 42 416 8.83E-59 T 23-10-2018 IPR028082 Periplasmic binding protein-like I TON_0162 db40a0cac65af3b9f42cbae900bafc44 428 Gene3D G3DSA:3.40.50.2300 43 392 5.5E-52 T 23-10-2018 TON_0162 db40a0cac65af3b9f42cbae900bafc44 428 Pfam PF13458 Periplasmic binding protein 42 410 1.4E-35 T 23-10-2018 IPR028081 Leucine-binding protein domain TON_0162 db40a0cac65af3b9f42cbae900bafc44 428 Gene3D G3DSA:3.40.50.2300 167 308 5.5E-52 T 23-10-2018 TON_0970 09be0965741fb32709eb809cae377599 196 SUPERFAMILY SSF53448 17 122 6.49E-6 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TON_0970 09be0965741fb32709eb809cae377599 196 Gene3D G3DSA:3.90.550.10 16 195 6.9E-12 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TON_0596 afa70116309902a489b288dd9b0c148e 344 PRINTS PR00173 Glutamate-aspartate symporter signature 4 29 4.1E-5 T 23-10-2018 TON_0596 afa70116309902a489b288dd9b0c148e 344 PRINTS PR00173 Glutamate-aspartate symporter signature 302 322 4.1E-5 T 23-10-2018 TON_0596 afa70116309902a489b288dd9b0c148e 344 PRINTS PR00173 Glutamate-aspartate symporter signature 97 119 4.1E-5 T 23-10-2018 TON_0596 afa70116309902a489b288dd9b0c148e 344 PRINTS PR00173 Glutamate-aspartate symporter signature 142 161 4.1E-5 T 23-10-2018 TON_0596 afa70116309902a489b288dd9b0c148e 344 Pfam PF02653 Branched-chain amino acid transport system / permease component 55 327 5.3E-41 T 23-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TON_1561 9dab02b13a68da66a9e08de7bcdc893d 276 Pfam PF04432 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus 101 249 2.8E-28 T 23-10-2018 IPR007525 Coenzyme F420 hydrogenase/dehydrogenase beta subunit, C-terminal TON_1561 9dab02b13a68da66a9e08de7bcdc893d 276 Pfam PF04422 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term 16 89 1.1E-21 T 23-10-2018 IPR007516 Coenzyme F420 hydrogenase/dehydrogenase beta subunit, N-terminal TON_1193 bee30f2da59da176cf3dbb068a4317f7 146 Gene3D G3DSA:2.40.50.180 22 142 1.2E-40 T 23-10-2018 TON_1193 bee30f2da59da176cf3dbb068a4317f7 146 SMART SM00260 1 142 7.3E-48 T 23-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 TON_1193 bee30f2da59da176cf3dbb068a4317f7 146 SUPERFAMILY SSF50341 2 144 1.2E-37 T 23-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 TON_1193 bee30f2da59da176cf3dbb068a4317f7 146 Gene3D G3DSA:2.30.30.40 7 136 1.2E-40 T 23-10-2018 TON_1193 bee30f2da59da176cf3dbb068a4317f7 146 Pfam PF01584 CheW-like domain 5 144 1.4E-35 T 23-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 TON_0193 2482b70b508d955f61f16fe27cc889e9 68 Gene3D G3DSA:3.90.550.10 1 68 2.0E-21 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TON_0193 2482b70b508d955f61f16fe27cc889e9 68 SUPERFAMILY SSF53448 1 67 1.67E-21 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TON_0193 2482b70b508d955f61f16fe27cc889e9 68 Pfam PF00483 Nucleotidyl transferase 2 67 2.9E-11 T 23-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 TON_0690 6fe83ada827277fb06813bea801ff283 171 Pfam PF00994 Probable molybdopterin binding domain 17 161 5.1E-37 T 23-10-2018 IPR001453 MoaB/Mog domain TON_0690 6fe83ada827277fb06813bea801ff283 171 SMART SM00852 17 165 4.8E-30 T 23-10-2018 IPR001453 MoaB/Mog domain TON_0690 6fe83ada827277fb06813bea801ff283 171 ProSitePatterns PS01078 Molybdenum cofactor biosynthesis proteins signature 1. 76 89 - T 23-10-2018 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 TON_0690 6fe83ada827277fb06813bea801ff283 171 Gene3D G3DSA:3.40.980.10 12 171 3.2E-49 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily TON_0690 6fe83ada827277fb06813bea801ff283 171 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 14 160 4.3E-37 T 23-10-2018 IPR001453 MoaB/Mog domain TON_0690 6fe83ada827277fb06813bea801ff283 171 PIRSF PIRSF006443 1 171 2.2E-58 T 23-10-2018 IPR012245 Molybdenum cofactor biosynthesis protein MoaB GO:0006777 TON_0690 6fe83ada827277fb06813bea801ff283 171 SUPERFAMILY SSF53218 13 169 2.22E-44 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily TON_0091 f95da59333a67d9075ba9cac5f9e89db 175 Pfam PF01956 Integral membrane protein DUF106 14 173 1.9E-28 T 23-10-2018 IPR002809 Integral membrane protein EMC3/TMCO1-like GO:0016020 TON_0091 f95da59333a67d9075ba9cac5f9e89db 175 SMART SM01415 10 174 2.4E-19 T 23-10-2018 IPR002809 Integral membrane protein EMC3/TMCO1-like GO:0016020 TON_1936 610442e0446252418ce5ee85d4295b5a 319 SUPERFAMILY SSF48371 10 247 2.19E-18 T 23-10-2018 IPR016024 Armadillo-type fold TON_1936 610442e0446252418ce5ee85d4295b5a 319 Gene3D G3DSA:1.25.10.10 1 259 4.9E-88 T 23-10-2018 IPR011989 Armadillo-like helical TON_1912 4b9bdf1fbec0f94dbd12cbd3a1c5a3fa 61 Pfam PF06093 Spt4/RpoE2 zinc finger 3 61 1.3E-16 T 23-10-2018 IPR022800 Spt4/RpoE2 zinc finger Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-75955 TON_1912 4b9bdf1fbec0f94dbd12cbd3a1c5a3fa 61 SUPERFAMILY SSF63393 3 61 1.86E-22 T 23-10-2018 IPR029040 RNA polymerase subunit RPABC4/transcription elongation factor Spt4 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-75955 TON_1912 4b9bdf1fbec0f94dbd12cbd3a1c5a3fa 61 Gene3D G3DSA:2.20.28.90 1 61 1.0E-31 T 23-10-2018 IPR038589 Archaeal transcription elongation factor Spt4 superfamily TON_1912 4b9bdf1fbec0f94dbd12cbd3a1c5a3fa 61 Hamap MF_00949 Transcription elongation factor Spt4 [spt4]. 5 61 28.338 T 23-10-2018 IPR007178 Archaeal transcription elongation factor Spt4 GO:0006355 TON_1912 4b9bdf1fbec0f94dbd12cbd3a1c5a3fa 61 ProDom PD019197 RNA DNA-DIRECTED POLYMERASE SUBUNIT E'' POLYMERASE RPOE2 TRANSFERASE NUCLEOTIDYLTRANSFERASE E 18 60 5.0E-14 T 23-10-2018 IPR007178 Archaeal transcription elongation factor Spt4 GO:0006355 TON_1912 4b9bdf1fbec0f94dbd12cbd3a1c5a3fa 61 SMART SM01389 3 61 1.5E-29 T 23-10-2018 IPR022800 Spt4/RpoE2 zinc finger Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-75955 TON_1046 8f82c4b8d16b2f726af0aa964b9fed94 269 Pfam PF01889 Membrane protein of unknown function DUF63 4 269 2.2E-85 T 23-10-2018 IPR002749 Protein of unknown function DUF63 TON_0723 c45b871016d1910ddc18f42685a1f078 148 Gene3D G3DSA:3.40.50.1000 9 140 3.3E-9 T 23-10-2018 IPR023214 HAD superfamily TON_0723 c45b871016d1910ddc18f42685a1f078 148 SUPERFAMILY SSF56784 12 130 1.36E-11 T 23-10-2018 IPR036412 HAD-like superfamily TON_0314 6d1df96aa10aac46828cc4e734936491 222 TIGRFAM TIGR01091 upp: uracil phosphoribosyltransferase 15 218 7.5E-77 T 23-10-2018 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 TON_0314 6d1df96aa10aac46828cc4e734936491 222 Hamap MF_01218_A Uracil phosphoribosyltransferase [upp]. 9 217 40.447 T 23-10-2018 IPR034331 Uracil phosphoribosyltransferase, archaea GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 TON_0314 6d1df96aa10aac46828cc4e734936491 222 SUPERFAMILY SSF53271 13 217 6.39E-57 T 23-10-2018 IPR029057 Phosphoribosyltransferase-like TON_0314 6d1df96aa10aac46828cc4e734936491 222 Gene3D G3DSA:3.40.50.2020 13 217 2.6E-59 T 23-10-2018 TON_0314 6d1df96aa10aac46828cc4e734936491 222 Pfam PF14681 Uracil phosphoribosyltransferase 15 218 8.0E-50 T 23-10-2018 TON_1764 a03c8fe7a1006678e0a24e14789e235c 810 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 244 706 4.2E-19 T 23-10-2018 IPR000914 Solute-binding protein family 5 domain TON_1764 a03c8fe7a1006678e0a24e14789e235c 810 Gene3D G3DSA:3.10.105.10 531 746 3.1E-17 T 23-10-2018 TON_1764 a03c8fe7a1006678e0a24e14789e235c 810 SUPERFAMILY SSF53850 273 723 7.6E-23 T 23-10-2018 TON_1250 352cc0aba821e94715da27641f3ff5a0 200 Pfam PF14544 Domain of unknown function (DUF4443) 80 191 3.8E-53 T 23-10-2018 IPR029349 Domain of unknown function DUF4443 TON_1250 352cc0aba821e94715da27641f3ff5a0 200 Gene3D G3DSA:1.10.10.10 1 82 1.0E-23 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TON_1250 352cc0aba821e94715da27641f3ff5a0 200 SUPERFAMILY SSF46785 17 76 1.34E-10 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TON_1250 352cc0aba821e94715da27641f3ff5a0 200 SUPERFAMILY SSF55261 87 198 5.23E-38 T 23-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 TON_1250 352cc0aba821e94715da27641f3ff5a0 200 Gene3D G3DSA:3.30.1360.30 83 191 9.7E-43 T 23-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 TON_1458 93b4047cd62c21c64a5b6f9148fe170a 425 PRINTS PR00758 Arsenical pump membrane protein signature 361 386 2.5E-14 T 23-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 TON_1458 93b4047cd62c21c64a5b6f9148fe170a 425 PRINTS PR00758 Arsenical pump membrane protein signature 394 418 2.5E-14 T 23-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 TON_1458 93b4047cd62c21c64a5b6f9148fe170a 425 PRINTS PR00758 Arsenical pump membrane protein signature 100 124 2.5E-14 T 23-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 TON_1458 93b4047cd62c21c64a5b6f9148fe170a 425 PRINTS PR00758 Arsenical pump membrane protein signature 321 343 2.5E-14 T 23-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 TON_1458 93b4047cd62c21c64a5b6f9148fe170a 425 PRINTS PR00758 Arsenical pump membrane protein signature 220 245 2.5E-14 T 23-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 TON_1458 93b4047cd62c21c64a5b6f9148fe170a 425 PRINTS PR00758 Arsenical pump membrane protein signature 277 301 2.5E-14 T 23-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 TON_1458 93b4047cd62c21c64a5b6f9148fe170a 425 Pfam PF03600 Citrate transporter 15 365 1.7E-51 T 23-10-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 TON_0284 efbad9f133ab6b9724c64d35608bdde6 118 Gene3D G3DSA:3.40.50.11740 59 114 7.7E-29 T 23-10-2018 TON_0284 efbad9f133ab6b9724c64d35608bdde6 118 Gene3D G3DSA:3.40.50.11750 15 58 7.7E-29 T 23-10-2018 TON_0284 efbad9f133ab6b9724c64d35608bdde6 118 Pfam PF01924 Hydrogenase formation hypA family 10 114 6.8E-33 T 23-10-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 TON_0829 4e40d8eed456c1d740cbd12aacb17503 216 Gene3D G3DSA:3.30.1020.10 145 216 3.2E-36 T 23-10-2018 TON_0829 4e40d8eed456c1d740cbd12aacb17503 216 SUPERFAMILY SSF52833 1 215 3.08E-65 T 23-10-2018 IPR036249 Thioredoxin-like superfamily TON_0829 4e40d8eed456c1d740cbd12aacb17503 216 Gene3D G3DSA:3.40.30.10 1 144 9.4E-45 T 23-10-2018 TON_0829 4e40d8eed456c1d740cbd12aacb17503 216 PIRSF PIRSF000239 1 215 1.3E-72 T 23-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 TON_0829 4e40d8eed456c1d740cbd12aacb17503 216 Pfam PF00578 AhpC/TSA family 4 134 9.4E-32 T 23-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 TON_0829 4e40d8eed456c1d740cbd12aacb17503 216 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 155 195 2.2E-11 T 23-10-2018 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 TON_0829 4e40d8eed456c1d740cbd12aacb17503 216 Hamap MF_00401 Peroxiredoxin. 2 215 52.379 T 23-10-2018 IPR022915 Peroxiredoxin, TDXH subfamily GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 TON_0589 50684e894b848c69f588b84883b00ae3 323 TIGRFAM TIGR01210 TIGR01210: radical SAM enzyme, TIGR01210 family 3 320 3.1E-119 T 23-10-2018 IPR005909 Conserved hypothetical protein CHP01210 TON_0589 50684e894b848c69f588b84883b00ae3 323 Pfam PF04055 Radical SAM superfamily 35 179 1.8E-8 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TON_0589 50684e894b848c69f588b84883b00ae3 323 SMART SM00729 17 246 2.0E-25 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TON_0589 50684e894b848c69f588b84883b00ae3 323 PIRSF PIRSF004954 1 318 8.2E-97 T 23-10-2018 IPR005909 Conserved hypothetical protein CHP01210 TON_0589 50684e894b848c69f588b84883b00ae3 323 SUPERFAMILY SSF102114 16 254 3.53E-17 T 23-10-2018 TON_1567 692bbb11c89462894232c96a2fd6607e 690 Pfam PF00361 Proton-conducting membrane transporter 133 432 1.1E-52 T 23-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_1567 692bbb11c89462894232c96a2fd6607e 690 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 237 261 2.2E-9 T 23-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_1567 692bbb11c89462894232c96a2fd6607e 690 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 389 415 2.2E-9 T 23-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_1567 692bbb11c89462894232c96a2fd6607e 690 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 169 193 2.2E-9 T 23-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_1959 5690edd6905a73c9dc186290dafd4168 539 SUPERFAMILY SSF161098 287 534 2.51E-55 T 23-10-2018 IPR035906 MetI-like superfamily TON_1959 5690edd6905a73c9dc186290dafd4168 539 SUPERFAMILY SSF161098 3 256 6.98E-53 T 23-10-2018 IPR035906 MetI-like superfamily TON_1959 5690edd6905a73c9dc186290dafd4168 539 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 72 256 1.3E-17 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TON_1959 5690edd6905a73c9dc186290dafd4168 539 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 365 533 9.7E-14 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TON_1959 5690edd6905a73c9dc186290dafd4168 539 Gene3D G3DSA:1.10.3720.10 2 261 1.2E-60 T 23-10-2018 IPR035906 MetI-like superfamily TON_1959 5690edd6905a73c9dc186290dafd4168 539 Gene3D G3DSA:1.10.3720.10 284 538 1.4E-55 T 23-10-2018 IPR035906 MetI-like superfamily TON_0488 c9992bb2db4e91dcd79cd4f8d9961cc5 177 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 36 155 7.2E-25 T 23-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_0488 c9992bb2db4e91dcd79cd4f8d9961cc5 177 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 87 129 1.0E-17 T 23-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_0488 c9992bb2db4e91dcd79cd4f8d9961cc5 177 SUPERFAMILY SSF143243 28 165 9.94E-30 T 23-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_0488 c9992bb2db4e91dcd79cd4f8d9961cc5 177 Gene3D G3DSA:3.30.460.80 3 133 1.4E-24 T 23-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_0019 c5b178b4c045f9b42d343db810f145c1 227 Pfam PF13680 Protein of unknown function (DUF4152) 1 224 1.6E-126 T 23-10-2018 IPR025206 Protein of unknown function DUF4152 TON_0019 c5b178b4c045f9b42d343db810f145c1 227 Gene3D G3DSA:3.30.420.440 1 227 2.4E-107 T 23-10-2018 TON_1814 c197f282fe64c1adbb0eb0adc64672f4 988 Gene3D G3DSA:3.90.70.10 86 345 2.3E-39 T 23-10-2018 TON_1814 c197f282fe64c1adbb0eb0adc64672f4 988 ProSitePatterns PS00639 Eukaryotic thiol (cysteine) proteases histidine active site. 293 303 - T 23-10-2018 IPR025660 Cysteine peptidase, histidine active site Reactome: R-HSA-2132295 TON_1814 c197f282fe64c1adbb0eb0adc64672f4 988 SUPERFAMILY SSF54001 76 355 1.1E-31 T 23-10-2018 IPR038765 Papain-like cysteine peptidase superfamily TON_1814 c197f282fe64c1adbb0eb0adc64672f4 988 Pfam PF00112 Papain family cysteine protease 266 338 7.2E-9 T 23-10-2018 IPR000668 Peptidase C1A, papain C-terminal GO:0006508|GO:0008234 TON_1814 c197f282fe64c1adbb0eb0adc64672f4 988 Pfam PF08308 PEGA domain 709 774 9.0E-18 T 23-10-2018 IPR013229 PEGA TON_0122 d839acc2756d92bdff92708df5a9140f 79 SUPERFAMILY SSF54909 2 75 6.44E-16 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel TON_0122 d839acc2756d92bdff92708df5a9140f 79 Gene3D G3DSA:3.30.70.920 1 74 6.1E-21 T 23-10-2018 TON_0122 d839acc2756d92bdff92708df5a9140f 79 Pfam PF01037 Lrp/AsnC ligand binding domain 6 74 2.3E-16 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain TON_0551 063d83efb0656fd59d3630e6dbe86883 264 Gene3D G3DSA:1.10.10.10 1 75 5.7E-7 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TON_0551 063d83efb0656fd59d3630e6dbe86883 264 Pfam PF08350 Domain of unknown function (DUF1724) 202 261 9.5E-20 T 23-10-2018 IPR013561 Domain of unknown function DUF1724 TON_0551 063d83efb0656fd59d3630e6dbe86883 264 SUPERFAMILY SSF46785 13 115 7.68E-11 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TON_0551 063d83efb0656fd59d3630e6dbe86883 264 Pfam PF01022 Bacterial regulatory protein, arsR family 15 54 5.3E-5 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TON_0551 063d83efb0656fd59d3630e6dbe86883 264 PIRSF PIRSF006692 1 264 6.1E-66 T 23-10-2018 IPR016490 Transcriptional regulator, HTH, AF0396-type TON_0680 653a815cf2f349962013830e50478f10 248 Gene3D G3DSA:3.40.470.10 69 245 1.5E-25 T 23-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 TON_0680 653a815cf2f349962013830e50478f10 248 SMART SM00986 104 237 1.9E-11 T 23-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 TON_0680 653a815cf2f349962013830e50478f10 248 SMART SM00987 104 237 1.9E-11 T 23-10-2018 TON_0680 653a815cf2f349962013830e50478f10 248 SUPERFAMILY SSF52141 97 244 3.04E-26 T 23-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 TON_0680 653a815cf2f349962013830e50478f10 248 Pfam PF03167 Uracil DNA glycosylase superfamily 110 223 1.5E-20 T 23-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 TON_1156 54b8654621109c63409a0947638be52b 202 Gene3D G3DSA:3.40.50.150 21 197 2.1E-34 T 23-10-2018 TON_1156 54b8654621109c63409a0947638be52b 202 SUPERFAMILY SSF53335 4 179 1.19E-31 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TON_1156 54b8654621109c63409a0947638be52b 202 Pfam PF08241 Methyltransferase domain 43 133 1.9E-17 T 23-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 TON_1828 d3b8562c2e1d64592c4c3d059a9d3c99 329 PIRSF PIRSF018671 1 329 1.9E-120 T 23-10-2018 IPR014495 Uncharacterised conserved protein UCP018671 TON_1828 d3b8562c2e1d64592c4c3d059a9d3c99 329 Pfam PF07760 Protein of unknown function (DUF1616) 11 324 2.5E-91 T 23-10-2018 IPR011674 Domain of unknown function DUF1616 TON_1853 9b3c936e8e62d0f42007295777ffccc0 189 Gene3D G3DSA:3.40.50.150 1 188 5.1E-15 T 23-10-2018 TON_1853 9b3c936e8e62d0f42007295777ffccc0 189 SUPERFAMILY SSF53335 4 137 2.64E-19 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TON_1853 9b3c936e8e62d0f42007295777ffccc0 189 Pfam PF13489 Methyltransferase domain 4 123 1.6E-12 T 23-10-2018 TON_1293 41b2814292537b6a05e15c00d75454c5 280 SMART SM00729 18 225 2.1E-9 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TON_1293 41b2814292537b6a05e15c00d75454c5 280 Gene3D G3DSA:3.80.30.30 51 257 1.1E-12 T 23-10-2018 TON_1293 41b2814292537b6a05e15c00d75454c5 280 Pfam PF04055 Radical SAM superfamily 23 187 6.4E-14 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TON_1293 41b2814292537b6a05e15c00d75454c5 280 SUPERFAMILY SSF102114 9 242 1.44E-15 T 23-10-2018 TON_0271 d43a20b1bb4bfd20a6f62fec803cc853 118 TIGRFAM TIGR01300 CPA3_mnhG_phaG: monovalent cation/proton antiporter, MnhG/PhaG subunit 11 111 6.2E-28 T 23-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 TON_0271 d43a20b1bb4bfd20a6f62fec803cc853 118 Pfam PF03334 Na+/H+ antiporter subunit 11 97 3.4E-16 T 23-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 TON_1930 185431a6a6ad7e7d1caac02c70cd40e9 258 Pfam PF13630 SdpI/YhfL protein family 25 86 2.4E-12 T 23-10-2018 IPR025962 SdpI/YhfL protein family TON_1930 185431a6a6ad7e7d1caac02c70cd40e9 258 Pfam PF07853 Protein of unknown function (DUF1648) 130 174 1.6E-16 T 23-10-2018 IPR012867 Domain of unknown function DUF1648 TON_0035 f7d0dbe04aed20afb778de847f6ca1ae 174 SUPERFAMILY SSF88697 3 143 1.01E-15 T 23-10-2018 IPR015947 PUA-like superfamily TON_0035 f7d0dbe04aed20afb778de847f6ca1ae 174 Pfam PF04266 ASCH domain 6 86 1.4E-5 T 23-10-2018 IPR007374 ASCH domain TON_0035 f7d0dbe04aed20afb778de847f6ca1ae 174 SMART SM01022 5 105 5.6E-6 T 23-10-2018 IPR007374 ASCH domain TON_1933 e200ad71530b7fbeb3b18c94b46af8b5 109 Pfam PF01906 Putative heavy-metal-binding 4 106 1.8E-34 T 23-10-2018 IPR002765 Uncharacterised protein family UPF0145 TON_1933 e200ad71530b7fbeb3b18c94b46af8b5 109 SUPERFAMILY SSF117782 4 108 1.83E-34 T 23-10-2018 IPR035439 UPF0145 domain superfamily TON_1933 e200ad71530b7fbeb3b18c94b46af8b5 109 Hamap MF_00338 UPF0145 protein YbjQ [ybjQ]. 4 106 24.252 T 23-10-2018 IPR002765 Uncharacterised protein family UPF0145 TON_1933 e200ad71530b7fbeb3b18c94b46af8b5 109 Gene3D G3DSA:3.30.110.70 4 109 4.2E-30 T 23-10-2018 TON_1497 8868925b145a50bc7db3a5be0483b67d 375 ProDom PD014260 DIHYDROOROTATE DEHYDROGENASE THERMOPHILE-SPECIFIC TA1428 ST0318 BLL2851 16-BISPHOSPHATASE APE1109 PF0613 MJ0299 6 371 0.0 T 23-10-2018 IPR002803 Fructose-1,6-bisphosphatase, class V KEGG: 00010+4.1.2.13+3.1.3.11|KEGG: 00030+4.1.2.13+3.1.3.11|KEGG: 00051+4.1.2.13+3.1.3.11|KEGG: 00680+4.1.2.13+3.1.3.11|KEGG: 00710+4.1.2.13+3.1.3.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 TON_1497 8868925b145a50bc7db3a5be0483b67d 375 Pfam PF01950 Fructose-1,6-bisphosphatase 6 372 1.2E-186 T 23-10-2018 IPR002803 Fructose-1,6-bisphosphatase, class V KEGG: 00010+4.1.2.13+3.1.3.11|KEGG: 00030+4.1.2.13+3.1.3.11|KEGG: 00051+4.1.2.13+3.1.3.11|KEGG: 00680+4.1.2.13+3.1.3.11|KEGG: 00710+4.1.2.13+3.1.3.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 TON_1497 8868925b145a50bc7db3a5be0483b67d 375 Hamap MF_02067 Fructose-1,6-bisphosphate aldolase/phosphatase [fbp]. 5 372 62.08 T 23-10-2018 IPR002803 Fructose-1,6-bisphosphatase, class V KEGG: 00010+4.1.2.13+3.1.3.11|KEGG: 00030+4.1.2.13+3.1.3.11|KEGG: 00051+4.1.2.13+3.1.3.11|KEGG: 00680+4.1.2.13+3.1.3.11|KEGG: 00710+4.1.2.13+3.1.3.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 TON_1497 8868925b145a50bc7db3a5be0483b67d 375 PIRSF PIRSF015647 5 375 4.3E-192 T 23-10-2018 IPR002803 Fructose-1,6-bisphosphatase, class V KEGG: 00010+4.1.2.13+3.1.3.11|KEGG: 00030+4.1.2.13+3.1.3.11|KEGG: 00051+4.1.2.13+3.1.3.11|KEGG: 00680+4.1.2.13+3.1.3.11|KEGG: 00710+4.1.2.13+3.1.3.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 TON_1497 8868925b145a50bc7db3a5be0483b67d 375 SUPERFAMILY SSF111249 6 372 7.59E-178 T 23-10-2018 IPR036076 Fructose-1,6-bisphosphatase, class V superfamily KEGG: 00010+3.1.3.11+4.1.2.13|KEGG: 00030+3.1.3.11+4.1.2.13|KEGG: 00051+3.1.3.11+4.1.2.13|KEGG: 00680+3.1.3.11+4.1.2.13|KEGG: 00710+3.1.3.11+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 TON_0115 10f45fedc6ad18bebf364ce861eede7e 99 Pfam PF04930 FUN14 family 12 96 2.7E-12 T 23-10-2018 IPR007014 FUN14 TON_0580 d6cc02df2264ade98861957ba4e037e0 115 SUPERFAMILY SSF55620 1 114 4.39E-32 T 23-10-2018 TON_0580 d6cc02df2264ade98861957ba4e037e0 115 PIRSF PIRSF006113 1 115 7.4E-34 T 23-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 TON_0580 d6cc02df2264ade98861957ba4e037e0 115 Gene3D G3DSA:3.30.479.10 1 115 1.7E-38 T 23-10-2018 IPR038418 6-pyruvoyl tetrahydropterin synthase/QueD superfamily Reactome: R-HSA-1474151 TON_0580 d6cc02df2264ade98861957ba4e037e0 115 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 5 113 5.4E-27 T 23-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 TON_1863 e8c0ec3bd18ff35c14fcf2ca7fe9fabf 263 Pfam PF09407 AbiEi antitoxin C-terminal domain 87 204 6.1E-5 T 23-10-2018 IPR018547 AbiEi antitoxin C-terminal domain TON_1863 e8c0ec3bd18ff35c14fcf2ca7fe9fabf 263 SUPERFAMILY SSF46785 4 61 1.74E-6 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TON_1652 bbad9ec90f9070881e1c9690819e9c3d 152 SUPERFAMILY SSF50199 29 145 1.18E-23 T 23-10-2018 TON_1652 bbad9ec90f9070881e1c9690819e9c3d 152 SMART SM00318 27 148 9.5E-7 T 23-10-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold Reactome: R-HSA-6802952 TON_1652 bbad9ec90f9070881e1c9690819e9c3d 152 Pfam PF00565 Staphylococcal nuclease homologue 57 143 3.1E-11 T 23-10-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold Reactome: R-HSA-6802952 TON_1652 bbad9ec90f9070881e1c9690819e9c3d 152 Gene3D G3DSA:2.40.50.90 23 148 7.3E-21 T 23-10-2018 IPR035437 SNase-like, OB-fold superfamily TON_0500 4d8dbaa2838aaaf7d4a22bebc5539bd7 419 Pfam PF04055 Radical SAM superfamily 123 287 2.7E-27 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TON_0500 4d8dbaa2838aaaf7d4a22bebc5539bd7 419 SUPERFAMILY SSF102114 109 325 3.14E-39 T 23-10-2018 TON_0500 4d8dbaa2838aaaf7d4a22bebc5539bd7 419 SMART SM00729 115 330 3.2E-15 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TON_0500 4d8dbaa2838aaaf7d4a22bebc5539bd7 419 Gene3D G3DSA:3.20.20.70 111 357 4.2E-39 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TON_0781 a0bf62acc0a957ff19d9bbb8cb290552 148 Pfam PF10015 Uncharacterized protein conserved in archaea (DUF2258) 3 73 4.2E-23 T 23-10-2018 IPR017140 Uncharacterised conserved protein UCP037214 TON_0195 bf18c4681dd96f469551c94742572fea 235 Gene3D G3DSA:3.40.120.10 3 78 3.6E-6 T 23-10-2018 TON_0195 bf18c4681dd96f469551c94742572fea 235 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 8 68 3.6E-5 T 23-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TON_0195 bf18c4681dd96f469551c94742572fea 235 SUPERFAMILY SSF53738 128 207 1.71E-6 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TON_0195 bf18c4681dd96f469551c94742572fea 235 SUPERFAMILY SSF53738 8 76 8.24E-7 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TON_0306 d857ee928b5a84af66710ce2f8ee4076 388 SUPERFAMILY SSF50249 332 383 6.43E-6 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold TON_0306 d857ee928b5a84af66710ce2f8ee4076 388 Pfam PF04981 NMD3 family 6 276 2.0E-61 T 23-10-2018 IPR007064 Nmd3, N-terminal TON_0306 d857ee928b5a84af66710ce2f8ee4076 388 Gene3D G3DSA:2.40.50.140 331 387 2.2E-9 T 23-10-2018 TON_0544 ee90a3196847e810b98659674a37f099 406 SUPERFAMILY SSF56796 12 401 1.96E-105 T 23-10-2018 TON_0544 ee90a3196847e810b98659674a37f099 406 Gene3D G3DSA:1.20.1090.10 203 401 3.2E-44 T 23-10-2018 TON_0544 ee90a3196847e810b98659674a37f099 406 Pfam PF00465 Iron-containing alcohol dehydrogenase 21 377 6.7E-96 T 23-10-2018 IPR001670 Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 TON_0544 ee90a3196847e810b98659674a37f099 406 Gene3D G3DSA:3.40.50.1970 11 199 3.4E-49 T 23-10-2018 TON_1811 8286e2ec82dc617c42f42bcc3ca9659e 578 SUPERFAMILY SSF88713 9 230 1.0E-14 T 23-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 TON_1971 30b894f98317da9eeceaced0b3614f18 190 Pfam PF01944 Stage II sporulation protein M 17 184 7.9E-33 T 23-10-2018 IPR002798 Stage II sporulation protein M-like TON_1475 d803f99891bc5e228ce0a662de96e38f 320 Pfam PF01384 Phosphate transporter family 19 307 1.1E-69 T 23-10-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 TON_0875 2197475a82da2d23231719b067e851a2 117 SUPERFAMILY SSF103481 13 103 6.8E-5 T 23-10-2018 TON_1218 5b6604b5c9038518d329288536dbd6c9 134 PIRSF PIRSF004681 1 133 3.4E-40 T 23-10-2018 IPR001602 Uncharacterised protein family UPF0047 TON_1218 5b6604b5c9038518d329288536dbd6c9 134 TIGRFAM TIGR00149 TIGR00149_YjbQ: secondary thiamine-phosphate synthase enzyme 4 131 1.9E-41 T 23-10-2018 IPR001602 Uncharacterised protein family UPF0047 TON_1218 5b6604b5c9038518d329288536dbd6c9 134 Pfam PF01894 Uncharacterised protein family UPF0047 17 131 2.1E-37 T 23-10-2018 IPR001602 Uncharacterised protein family UPF0047 TON_1218 5b6604b5c9038518d329288536dbd6c9 134 Gene3D G3DSA:2.60.120.460 1 133 2.5E-49 T 23-10-2018 IPR035917 YjbQ-like superfamily TON_1218 5b6604b5c9038518d329288536dbd6c9 134 SUPERFAMILY SSF111038 2 131 4.97E-41 T 23-10-2018 IPR035917 YjbQ-like superfamily TON_0658 22f470dfbd9063bef11a71ea19d4b11d 84 SUPERFAMILY SSF46785 1 63 4.14E-7 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TON_0658 22f470dfbd9063bef11a71ea19d4b11d 84 Gene3D G3DSA:1.10.10.10 2 56 1.7E-6 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TON_1577 023e1c9284f0aa1d1f62969ee7a523a4 251 Pfam PF04039 Domain related to MnhB subunit of Na+/H+ antiporter 107 230 1.4E-23 T 23-10-2018 IPR007182 Na+/H+ antiporter MnhB subunit-related protein TON_0302 13e0661af142265feb781114cbf73871 263 SUPERFAMILY SSF56524 40 159 1.37E-7 T 23-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 TON_1676 23b1f33dec134f394097759a0d647e53 355 Gene3D G3DSA:1.20.81.30 179 286 3.8E-12 T 23-10-2018 TON_1676 23b1f33dec134f394097759a0d647e53 355 Pfam PF00482 Type II secretion system (T2SS), protein F 186 311 2.3E-23 T 23-10-2018 IPR018076 Type II secretion system F domain TON_1632 1d42fafc49ee4147bc6c87cd141b5825 278 SUPERFAMILY SSF111331 2 275 4.84E-73 T 23-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily TON_1632 1d42fafc49ee4147bc6c87cd141b5825 278 Gene3D G3DSA:2.60.200.30 121 254 1.8E-69 T 23-10-2018 IPR017437 ATP-NAD kinase, PpnK-type, C-terminal GO:0003951|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 TON_1632 1d42fafc49ee4147bc6c87cd141b5825 278 Gene3D G3DSA:3.40.50.10330 20 267 1.8E-69 T 23-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 TON_1632 1d42fafc49ee4147bc6c87cd141b5825 278 Hamap MF_00361 NAD kinase [nadK]. 1 276 29.96 T 23-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 TON_1632 1d42fafc49ee4147bc6c87cd141b5825 278 Pfam PF01513 ATP-NAD kinase 2 261 8.3E-71 T 23-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 TON_1624 bfd178f954f2f391e813b93c56d105c0 170 Pfam PF01864 CDP-archaeol synthase 6 170 9.8E-58 T 23-10-2018 IPR032690 CDP-archaeol synthase KEGG: 00564+2.7.7.67|MetaCyc: PWY-6349 TON_1624 bfd178f954f2f391e813b93c56d105c0 170 Hamap MF_01117 CDP-archaeol synthase [carS]. 13 170 27.772 T 23-10-2018 IPR002726 CDP-archaeol synthase, archaea KEGG: 00564+2.7.7.67|MetaCyc: PWY-6349 TON_1447 590bf9da93a18103305d5613b998a5a3 567 TIGRFAM TIGR04288 CGP_CTERM: CGP-CTERM domain 547 566 1.6E-4 T 23-10-2018 IPR027552 CGP-CTERM domain TON_1832 8bd052a87444498edd2a1a374dade4fd 332 SUPERFAMILY SSF52317 72 233 8.01E-7 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like TON_1832 8bd052a87444498edd2a1a374dade4fd 332 Pfam PF14258 Domain of unknown function (DUF4350) 37 107 1.6E-9 T 23-10-2018 IPR025646 Domain of unknown function DUF4350 TON_1183 6cf30f2179c31f6bfb6de460d69c7e83 443 Pfam PF04659 Archaeal flagella protein 322 415 5.6E-29 T 23-10-2018 IPR006752 Archaeal flagella protein FlaD/E domain GO:0097588 TON_1183 6cf30f2179c31f6bfb6de460d69c7e83 443 ProDom PD012942 FLAGELLUM FLAGELLA-RELATED E D ACCESSORY FLAGELLA ARCHAEAL FLAD SIMILAR D 326 427 6.0E-52 T 23-10-2018 IPR006752 Archaeal flagella protein FlaD/E domain GO:0097588 TON_1183 6cf30f2179c31f6bfb6de460d69c7e83 443 PIRSF PIRSF017066 2 443 2.5E-139 T 23-10-2018 IPR016682 Flagella accessory protein D, predicted, archaeal TON_1677 e5f6ba8e0b2853aba37903bde13dd68f 304 Pfam PF00482 Type II secretion system (T2SS), protein F 105 229 9.4E-16 T 23-10-2018 IPR018076 Type II secretion system F domain TON_1677 e5f6ba8e0b2853aba37903bde13dd68f 304 Gene3D G3DSA:1.20.81.30 90 209 2.4E-6 T 23-10-2018 TON_0719 28034f6842362f171658a3132c3e277d 221 SUPERFAMILY SSF53448 5 209 1.55E-49 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TON_0719 28034f6842362f171658a3132c3e277d 221 Pfam PF00535 Glycosyl transferase family 2 8 164 1.2E-38 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TON_0719 28034f6842362f171658a3132c3e277d 221 Gene3D G3DSA:3.90.550.10 2 220 1.4E-59 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TON_1846 198967189960aff38fcb08cc07e0e31f 67 Pfam PF10047 Protein of unknown function (DUF2281) 5 61 6.1E-19 T 23-10-2018 IPR018739 Domain of unknown function DUF2281 TON_0599 3571f1dd3178919a4c322626abe98303 596 Pfam PF16286 Domain of unknown function (DUF4932) 29 204 1.8E-11 T 23-10-2018 IPR032560 Protein of unknown function DUF4932 TON_0599 3571f1dd3178919a4c322626abe98303 596 Pfam PF05124 S-layer like family, C-terminal region 454 564 1.3E-10 T 23-10-2018 IPR022651 S-layer protein, C-terminal TON_1669 6d9e86304d9ba87a2719acc57104d0fa 570 Pfam PF03169 OPT oligopeptide transporter protein 10 562 5.0E-67 T 23-10-2018 IPR004813 Oligopeptide transporter, OPT superfamily GO:0055085 TON_1669 6d9e86304d9ba87a2719acc57104d0fa 570 PRINTS PR00173 Glutamate-aspartate symporter signature 6 26 8.8E-6 T 23-10-2018 TON_1669 6d9e86304d9ba87a2719acc57104d0fa 570 PRINTS PR00173 Glutamate-aspartate symporter signature 259 278 8.8E-6 T 23-10-2018 TON_1669 6d9e86304d9ba87a2719acc57104d0fa 570 PRINTS PR00173 Glutamate-aspartate symporter signature 98 123 8.8E-6 T 23-10-2018 TON_1669 6d9e86304d9ba87a2719acc57104d0fa 570 PRINTS PR00173 Glutamate-aspartate symporter signature 388 407 8.8E-6 T 23-10-2018 TON_1839 da60446f012313d042341d8ff4033e2e 87 SUPERFAMILY SSF52540 4 86 2.23E-10 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_1839 da60446f012313d042341d8ff4033e2e 87 Gene3D G3DSA:3.40.50.300 1 82 2.0E-15 T 23-10-2018 TON_0398 41066ee39340832ed5ab8be3a2edae2b 247 Gene3D G3DSA:3.40.50.300 2 241 8.1E-48 T 23-10-2018 TON_0398 41066ee39340832ed5ab8be3a2edae2b 247 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 3 220 6.1E-20 T 23-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain TON_0398 41066ee39340832ed5ab8be3a2edae2b 247 SUPERFAMILY SSF52540 3 244 4.02E-48 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_1473 34694e0d9dfa16432519a95a108a6f0b 119 SUPERFAMILY SSF69118 10 109 1.7E-27 T 23-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 TON_1473 34694e0d9dfa16432519a95a108a6f0b 119 Gene3D G3DSA:1.20.1290.10 2 114 3.4E-30 T 23-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 TON_1473 34694e0d9dfa16432519a95a108a6f0b 119 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 43 86 1.7E-12 T 23-10-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 TON_1473 34694e0d9dfa16432519a95a108a6f0b 119 Pfam PF02627 Carboxymuconolactone decarboxylase family 29 106 2.5E-19 T 23-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 TON_0503 024503f30d6ee5a389685cc83e2df364 375 PIRSF PIRSF005357 1 346 5.2E-119 T 23-10-2018 IPR007152 Protein of unknown function DUF354 TON_0503 024503f30d6ee5a389685cc83e2df364 375 SUPERFAMILY SSF53756 1 317 4.71E-24 T 23-10-2018 TON_0503 024503f30d6ee5a389685cc83e2df364 375 Pfam PF04007 Protein of unknown function (DUF354) 1 338 5.6E-100 T 23-10-2018 IPR007152 Protein of unknown function DUF354 TON_0011 afcc955cffd2ff1f1d0b3318e4228bfc 96 SUPERFAMILY SSF46785 2 94 3.85E-27 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TON_0011 afcc955cffd2ff1f1d0b3318e4228bfc 96 Pfam PF03551 Transcriptional regulator PadR-like family 11 81 7.2E-19 T 23-10-2018 IPR005149 Transcription regulator PadR, N-terminal TON_0011 afcc955cffd2ff1f1d0b3318e4228bfc 96 Gene3D G3DSA:1.10.10.10 1 96 2.4E-26 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TON_0761 3ad154e23c9323a9959d7f281e6a89fa 136 SUPERFAMILY SSF46689 85 125 1.34E-6 T 23-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TON_0761 3ad154e23c9323a9959d7f281e6a89fa 136 Gene3D G3DSA:1.10.10.60 85 128 5.9E-8 T 23-10-2018 TON_0294 af38a539eb0dea658a5bd061d4b92d8e 80 Pfam PF14358 Domain of unknown function (DUF4405) 8 68 1.1E-9 T 23-10-2018 IPR025517 Domain of unknown function DUF4405 TON_1322 d401e9b2e9d7e1fd0855ce9a972f6fe5 282 Pfam PF01564 Spermine/spermidine synthase domain 64 241 6.2E-54 T 23-10-2018 TON_1322 d401e9b2e9d7e1fd0855ce9a972f6fe5 282 Gene3D G3DSA:2.30.140.10 6 60 1.1E-23 T 23-10-2018 IPR037163 Spermidine synthase, tetramerisation domain superfamily KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 TON_1322 d401e9b2e9d7e1fd0855ce9a972f6fe5 282 SUPERFAMILY SSF53335 10 280 7.41E-78 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TON_1322 d401e9b2e9d7e1fd0855ce9a972f6fe5 282 TIGRFAM TIGR00417 speE: spermidine synthase 10 274 6.7E-85 T 23-10-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 TON_1322 d401e9b2e9d7e1fd0855ce9a972f6fe5 282 ProSitePatterns PS01330 Polyamine biosynthesis (PABS) domain signature. 84 97 - T 23-10-2018 IPR030373 Polyamine biosynthesis domain, conserved site KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 TON_1322 d401e9b2e9d7e1fd0855ce9a972f6fe5 282 Hamap MF_00198 Polyamine aminopropyltransferase [speE]. 1 280 36.522 T 23-10-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 TON_1322 d401e9b2e9d7e1fd0855ce9a972f6fe5 282 Gene3D G3DSA:3.40.50.150 62 282 1.2E-75 T 23-10-2018 TON_1322 d401e9b2e9d7e1fd0855ce9a972f6fe5 282 Pfam PF17284 Spermidine synthase tetramerisation domain 10 60 1.0E-12 T 23-10-2018 IPR035246 Spermidine synthase, tetramerisation domain KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 TON_1507 cbca56d7778e950c67ad13a53b81ec30 98 Pfam PF09876 Predicted metal-binding protein (DUF2103) 5 93 3.1E-21 T 23-10-2018 IPR018664 Protein of unknown function DUF2103, metal-binding TON_0852 a78d749b6d621402c389945ae18d6359 174 Gene3D G3DSA:1.20.1260.10 1 174 2.3E-57 T 23-10-2018 IPR012347 Ferritin-like TON_0852 a78d749b6d621402c389945ae18d6359 174 SUPERFAMILY SSF47240 1 161 1.2E-62 T 23-10-2018 IPR009078 Ferritin-like superfamily TON_0852 a78d749b6d621402c389945ae18d6359 174 Pfam PF00210 Ferritin-like domain 7 142 2.6E-46 T 23-10-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 TON_0831 3219a50853296f769c6d5235014b59b7 234 Pfam PF12698 ABC-2 family transporter protein 40 217 1.0E-8 T 23-10-2018 TON_0230 4575e2c3923f17abcc705d9de29c1948 305 SUPERFAMILY SSF82171 108 251 3.02E-5 T 23-10-2018 TON_0524 5145e68b3fb9ba9667e13f82237112da 100 PIRSF PIRSF029904 1 100 2.4E-34 T 23-10-2018 IPR012359 NTP pyrophosphohydrolase MazG-related, YpjD TON_0524 5145e68b3fb9ba9667e13f82237112da 100 SUPERFAMILY SSF101386 2 95 4.07E-22 T 23-10-2018 TON_0524 5145e68b3fb9ba9667e13f82237112da 100 Gene3D G3DSA:1.10.287.1080 1 99 5.4E-26 T 23-10-2018 TON_0524 5145e68b3fb9ba9667e13f82237112da 100 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 23 95 9.3E-15 T 23-10-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core TON_0846 c8dd1508e2be8e9a4c52f9646c962139 285 Pfam PF03239 Iron permease FTR1 family 4 263 4.8E-65 T 23-10-2018 IPR004923 Iron permease FTR1/Fip1/EfeU GO:0005381|GO:0016020|GO:0033573|GO:0034755 TON_1326 878f15c480e4833fdb9ced1acd4e43cc 500 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 225 249 1.4E-10 T 23-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_1326 878f15c480e4833fdb9ced1acd4e43cc 500 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 308 327 1.4E-10 T 23-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_1326 878f15c480e4833fdb9ced1acd4e43cc 500 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 126 145 1.4E-10 T 23-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_1326 878f15c480e4833fdb9ced1acd4e43cc 500 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 156 180 1.4E-10 T 23-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_1326 878f15c480e4833fdb9ced1acd4e43cc 500 Pfam PF00361 Proton-conducting membrane transporter 120 398 3.7E-50 T 23-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_1131 9c6b3fed522c29a12b1c914105504e0f 216 SUPERFAMILY SSF52518 38 213 1.11E-54 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold TON_1131 9c6b3fed522c29a12b1c914105504e0f 216 Gene3D G3DSA:3.40.50.970 5 216 8.3E-65 T 23-10-2018 TON_1131 9c6b3fed522c29a12b1c914105504e0f 216 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 40 212 4.4E-27 T 23-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 TON_1741 f044407461cdda15b7529eede881ae38 202 TIGRFAM TIGR03879 near_KaiC_dom: probable regulatory domain 29 101 2.3E-25 T 23-10-2018 IPR022285 Conserved hypothetical protein CHP03879, regulatory domain, putative TON_1741 f044407461cdda15b7529eede881ae38 202 Gene3D G3DSA:1.10.10.60 55 83 5.4E-6 T 23-10-2018 TON_0605 3f6586924edfe730e615709be0c95ccc 250 Pfam PF07786 Protein of unknown function (DUF1624) 11 232 2.4E-65 T 23-10-2018 IPR012429 Domain of unknown function DUF1624 Reactome: R-HSA-2024096|Reactome: R-HSA-2206291|Reactome: R-HSA-6798695 TON_0013 79306913ab37fb8dcec49df2619619ee 132 Pfam PF09999 Uncharacterized protein conserved in archaea (DUF2240) 10 128 5.6E-8 T 23-10-2018 IPR018716 Protein of unknown function DUF2240 TON_1479 b1ceebcda9017ac354724d0069c37422 311 Gene3D G3DSA:3.40.50.970 12 101 1.4E-5 T 23-10-2018 TON_1479 b1ceebcda9017ac354724d0069c37422 311 Gene3D G3DSA:3.40.50.970 102 310 3.7E-69 T 23-10-2018 TON_1479 b1ceebcda9017ac354724d0069c37422 311 SUPERFAMILY SSF52518 16 308 6.55E-74 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold TON_1479 b1ceebcda9017ac354724d0069c37422 311 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 63 218 9.5E-21 T 23-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 TON_1530 a515b2a8aa15cc239eb76f3d4297de24 295 Gene3D G3DSA:3.40.1350.10 214 294 1.0E-6 T 23-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 TON_0485 e86fc075c883351c921f439d6aad25e7 194 Pfam PF06195 Protein of unknown function (DUF996) 38 170 7.7E-28 T 23-10-2018 IPR010397 Protein of unknown function DUF996 TON_0845 8570bb0d9c5c6b8955ba462718665c58 122 SUPERFAMILY SSF51735 5 120 1.32E-36 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TON_0845 8570bb0d9c5c6b8955ba462718665c58 122 SMART SM00881 2 95 7.3E-25 T 23-10-2018 IPR003781 CoA-binding GO:0048037 TON_0845 8570bb0d9c5c6b8955ba462718665c58 122 Gene3D G3DSA:3.40.50.720 2 122 3.9E-42 T 23-10-2018 TON_0845 8570bb0d9c5c6b8955ba462718665c58 122 Pfam PF13380 CoA binding domain 7 120 2.3E-34 T 23-10-2018 IPR003781 CoA-binding GO:0048037 TON_1291 67d677472051583e083f727782c096ba 213 TIGRFAM TIGR00427 TIGR00427: membrane protein, MarC family 3 207 2.3E-61 T 23-10-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 TON_1291 67d677472051583e083f727782c096ba 213 Pfam PF01914 MarC family integral membrane protein 6 211 2.7E-59 T 23-10-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 TON_1165 43e463175cb259d99c7cd9cf0914b7ba 257 PIRSF PIRSF006779 1 256 2.2E-78 T 23-10-2018 IPR002747 SAM-dependent chlorinase/fluorinase TON_1165 43e463175cb259d99c7cd9cf0914b7ba 257 Gene3D G3DSA:2.40.30.90 161 256 1.5E-33 T 23-10-2018 IPR023227 S-adenosyl-l-methionine hydroxide adenosyltransferase, C-terminal TON_1165 43e463175cb259d99c7cd9cf0914b7ba 257 Gene3D G3DSA:3.40.50.10790 1 160 4.8E-60 T 23-10-2018 IPR023228 S-adenosyl-l-methionine hydroxide adenosyltransferase, N-terminal TON_1165 43e463175cb259d99c7cd9cf0914b7ba 257 Pfam PF01887 S-adenosyl-l-methionine hydroxide adenosyltransferase 2 252 1.8E-75 T 23-10-2018 IPR002747 SAM-dependent chlorinase/fluorinase TON_1165 43e463175cb259d99c7cd9cf0914b7ba 257 SUPERFAMILY SSF102522 1 161 3.14E-54 T 23-10-2018 IPR023228 S-adenosyl-l-methionine hydroxide adenosyltransferase, N-terminal TON_1165 43e463175cb259d99c7cd9cf0914b7ba 257 SUPERFAMILY SSF101852 163 254 7.45E-24 T 23-10-2018 IPR023227 S-adenosyl-l-methionine hydroxide adenosyltransferase, C-terminal TON_1684 439a49d29763e3686b13012862eff0d9 435 Pfam PF01882 Protein of unknown function DUF58 215 294 5.8E-22 T 23-10-2018 IPR002881 Domain of unknown function DUF58 TON_0073 f3bf49e2f0e9a2a1646ed1a4c871f204 66 SUPERFAMILY SSF46561 1 61 1.26E-16 T 23-10-2018 IPR036049 Ribosomal protein L29/L35 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0073 f3bf49e2f0e9a2a1646ed1a4c871f204 66 TIGRFAM TIGR00012 L29: ribosomal protein uL29 5 61 1.1E-20 T 23-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0073 f3bf49e2f0e9a2a1646ed1a4c871f204 66 ProSitePatterns PS00579 Ribosomal protein L29 signature. 40 54 - T 23-10-2018 IPR018254 Ribosomal protein L29, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0073 f3bf49e2f0e9a2a1646ed1a4c871f204 66 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 1 61 16.061 T 23-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_0073 f3bf49e2f0e9a2a1646ed1a4c871f204 66 Gene3D G3DSA:1.10.287.310 1 66 1.2E-19 T 23-10-2018 TON_0073 f3bf49e2f0e9a2a1646ed1a4c871f204 66 Pfam PF00831 Ribosomal L29 protein 4 61 7.4E-18 T 23-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_1468 bce49bbce0f378473bcb96f048c7a993 345 Gene3D G3DSA:1.25.40.10 114 340 1.5E-15 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TON_1468 bce49bbce0f378473bcb96f048c7a993 345 Pfam PF13429 Tetratricopeptide repeat 168 317 5.8E-9 T 23-10-2018 TON_1468 bce49bbce0f378473bcb96f048c7a993 345 SUPERFAMILY SSF103473 7 110 3.92E-5 T 23-10-2018 IPR036259 MFS transporter superfamily TON_1468 bce49bbce0f378473bcb96f048c7a993 345 SUPERFAMILY SSF48452 135 333 5.69E-23 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TON_1450 cd3db464c9b8b81d31826bf8cbcec898 191 Pfam PF09851 Short C-terminal domain 161 188 1.7E-11 T 23-10-2018 IPR018649 SHOCT domain TON_1450 cd3db464c9b8b81d31826bf8cbcec898 191 Pfam PF14470 Bacterial PH domain 13 105 1.9E-20 T 23-10-2018 IPR039519 YokE-like, PH domain TON_0417 d6d59e89ef2f46b560f36c2218ad2a9b 407 Pfam PF00534 Glycosyl transferases group 1 195 365 2.0E-24 T 23-10-2018 IPR001296 Glycosyl transferase, family 1 TON_0417 d6d59e89ef2f46b560f36c2218ad2a9b 407 Pfam PF13439 Glycosyltransferase Family 4 17 185 1.2E-28 T 23-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 TON_0417 d6d59e89ef2f46b560f36c2218ad2a9b 407 Gene3D G3DSA:3.40.50.2000 183 372 2.1E-77 T 23-10-2018 TON_0417 d6d59e89ef2f46b560f36c2218ad2a9b 407 SUPERFAMILY SSF53756 5 384 1.14E-74 T 23-10-2018 TON_0417 d6d59e89ef2f46b560f36c2218ad2a9b 407 Gene3D G3DSA:3.40.50.2000 8 373 2.1E-77 T 23-10-2018 TON_1292 c865bdc38442fb42a7d3bbee4c1b943d 135 Gene3D G3DSA:3.30.300.20 4 134 4.1E-34 T 23-10-2018 IPR015946 K homology domain-like, alpha/beta TON_1292 c865bdc38442fb42a7d3bbee4c1b943d 135 Pfam PF02566 OsmC-like protein 32 119 5.9E-16 T 23-10-2018 IPR003718 OsmC/Ohr family TON_1292 c865bdc38442fb42a7d3bbee4c1b943d 135 SUPERFAMILY SSF82784 8 133 4.84E-32 T 23-10-2018 IPR036102 OsmC/Ohr superfamily TON_0344 f5dee55af0ffd99e3d6dbf01bfd45039 682 Pfam PF05753 Translocon-associated protein beta (TRAPB) 337 455 2.0E-7 T 23-10-2018 TON_1888 17f1f034869225c8488384ef8b6c29cc 436 Pfam PF13173 AAA domain 35 165 2.8E-34 T 23-10-2018 TON_1888 17f1f034869225c8488384ef8b6c29cc 436 SUPERFAMILY SSF52540 22 227 1.36E-19 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_1888 17f1f034869225c8488384ef8b6c29cc 436 Pfam PF13635 Domain of unknown function (DUF4143) 223 373 5.4E-17 T 23-10-2018 IPR025420 Domain of unknown function DUF4143 TON_1701 68ba896967e69497d55be9cf9e06193d 341 Gene3D G3DSA:3.40.50.720 8 311 5.4E-108 T 23-10-2018 TON_1701 68ba896967e69497d55be9cf9e06193d 341 Pfam PF02719 Polysaccharide biosynthesis protein 11 294 8.5E-90 T 23-10-2018 IPR003869 Polysaccharide biosynthesis protein, CapD-like domain TON_1701 68ba896967e69497d55be9cf9e06193d 341 Gene3D G3DSA:3.90.25.30 171 323 5.4E-108 T 23-10-2018 TON_1701 68ba896967e69497d55be9cf9e06193d 341 SUPERFAMILY SSF51735 8 245 4.91E-51 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TON_1163 7fdd722980dab8510f62d0aee0bceb95 135 SUPERFAMILY SSF81301 19 112 2.36E-8 T 23-10-2018 TON_1163 7fdd722980dab8510f62d0aee0bceb95 135 Gene3D G3DSA:3.30.460.10 5 117 3.6E-11 T 23-10-2018 TON_1163 7fdd722980dab8510f62d0aee0bceb95 135 Pfam PF01909 Nucleotidyltransferase domain 10 55 7.0E-7 T 23-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 TON_0740 e26ee86b49d27fce04b9f7ab1940ed5c 135 Gene3D G3DSA:3.10.580.10 1 135 2.4E-44 T 23-10-2018 TON_0740 e26ee86b49d27fce04b9f7ab1940ed5c 135 SMART SM00116 78 125 5.0E-8 T 23-10-2018 IPR000644 CBS domain TON_0740 e26ee86b49d27fce04b9f7ab1940ed5c 135 SMART SM00116 14 61 5.9E-11 T 23-10-2018 IPR000644 CBS domain TON_0740 e26ee86b49d27fce04b9f7ab1940ed5c 135 Pfam PF00571 CBS domain 71 123 8.2E-15 T 23-10-2018 IPR000644 CBS domain TON_0740 e26ee86b49d27fce04b9f7ab1940ed5c 135 Pfam PF00571 CBS domain 10 60 5.3E-10 T 23-10-2018 IPR000644 CBS domain TON_0740 e26ee86b49d27fce04b9f7ab1940ed5c 135 SUPERFAMILY SSF54631 7 127 2.78E-31 T 23-10-2018 TON_1346 02a10ce625eb5ba6f6e437bbbe816ca7 135 Hamap MF_01112 UPF0201 protein . 3 132 25.166 T 23-10-2018 IPR002739 Uncharacterised protein family UPF0201 TON_1346 02a10ce625eb5ba6f6e437bbbe816ca7 135 Pfam PF01877 RNA binding 4 113 5.9E-18 T 23-10-2018 IPR002739 Uncharacterised protein family UPF0201 TON_1346 02a10ce625eb5ba6f6e437bbbe816ca7 135 SUPERFAMILY SSF55282 4 134 1.24E-40 T 23-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_1346 02a10ce625eb5ba6f6e437bbbe816ca7 135 Gene3D G3DSA:3.30.1440.10 1 134 6.9E-45 T 23-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_1235 9ec6c214b3ff80666751218890a3ac2c 67 Pfam PF00808 Histone-like transcription factor (CBF/NF-Y) and archaeal histone 2 65 4.1E-21 T 23-10-2018 IPR003958 Transcription factor CBF/NF-Y/archaeal histone domain TON_1235 9ec6c214b3ff80666751218890a3ac2c 67 SUPERFAMILY SSF47113 3 66 9.69E-20 T 23-10-2018 IPR009072 Histone-fold GO:0046982 TON_1235 9ec6c214b3ff80666751218890a3ac2c 67 SMART SM00803 12 66 0.002 T 23-10-2018 IPR004823 TATA box binding protein associated factor (TAF) GO:0006352 TON_1235 9ec6c214b3ff80666751218890a3ac2c 67 Gene3D G3DSA:1.10.20.10 1 67 1.1E-22 T 23-10-2018 IPR009072 Histone-fold GO:0046982 TON_1109 7a771407e4fcb5195ceae829f016aab5 51 Gene3D G3DSA:1.10.1620.10 2 51 1.1E-18 T 23-10-2018 IPR023626 Ribosomal protein L39e domain superfamily TON_1109 7a771407e4fcb5195ceae829f016aab5 51 SUPERFAMILY SSF48662 4 50 1.44E-18 T 23-10-2018 IPR023626 Ribosomal protein L39e domain superfamily TON_1109 7a771407e4fcb5195ceae829f016aab5 51 Hamap MF_00629 50S ribosomal protein L39e [rpl39e]. 1 51 19.186 T 23-10-2018 IPR000077 Ribosomal protein L39e GO:0003735|GO:0005622|GO:0005840|GO:0006412 TON_1109 7a771407e4fcb5195ceae829f016aab5 51 Pfam PF00832 Ribosomal L39 protein 9 50 2.2E-21 T 23-10-2018 IPR000077 Ribosomal protein L39e GO:0003735|GO:0005622|GO:0005840|GO:0006412 TON_0964 ad0055c910878b2afa9c83a8a6d296cf 311 Pfam PF01699 Sodium/calcium exchanger protein 165 303 9.2E-26 T 23-10-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 TON_0964 ad0055c910878b2afa9c83a8a6d296cf 311 Pfam PF01699 Sodium/calcium exchanger protein 5 143 1.3E-25 T 23-10-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 TON_0964 ad0055c910878b2afa9c83a8a6d296cf 311 TIGRFAM TIGR00367 TIGR00367: K+-dependent Na+/Ca+ exchanger homolog 3 299 1.7E-62 T 23-10-2018 IPR004481 Sodium/potassium/calcium exchanger Reactome: R-HSA-425561 TON_0964 ad0055c910878b2afa9c83a8a6d296cf 311 Gene3D G3DSA:1.20.58.1130 8 195 3.1E-81 T 23-10-2018 TON_0964 ad0055c910878b2afa9c83a8a6d296cf 311 Gene3D G3DSA:1.20.1420.30 35 297 3.1E-81 T 23-10-2018 TON_1631 f4c1c73dd5dd0853a64a498b7250a414 348 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 11 321 3.2E-62 T 23-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD TON_1631 f4c1c73dd5dd0853a64a498b7250a414 348 TIGRFAM TIGR00374 TIGR00374: TIGR00374 family protein 11 338 2.7E-66 T 23-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD TON_0334 0d669a9442b24e5b5dbe258c99ce5164 109 Pfam PF06677 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) 18 50 5.1E-13 T 23-10-2018 IPR009563 Sjoegren syndrome/scleroderma autoantigen 1 TON_0802 d23a7424026ac88032f778e2802ac684 97 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 25 82 7.6E-14 T 23-10-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core TON_0802 d23a7424026ac88032f778e2802ac684 97 Gene3D G3DSA:1.10.287.1080 1 79 1.2E-27 T 23-10-2018 TON_0802 d23a7424026ac88032f778e2802ac684 97 SUPERFAMILY SSF101386 1 79 3.78E-21 T 23-10-2018 TON_1545 6a6b9c33e41d4d82940a2a439d7e6c75 215 SUPERFAMILY SSF56112 7 154 1.42E-14 T 23-10-2018 IPR011009 Protein kinase-like domain superfamily TON_0683 6acf2ca4d1ea5ee2469c73bc45f8a2dd 136 TIGRFAM TIGR03161 ribazole_CobZ: alpha-ribazole phosphatase CobZ 8 132 8.6E-52 T 23-10-2018 IPR017577 Alpha-ribazole phosphatase, CobZ TON_0683 6acf2ca4d1ea5ee2469c73bc45f8a2dd 136 Pfam PF04608 Phosphatidylglycerophosphatase A 14 133 3.1E-10 T 23-10-2018 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 TON_0683 6acf2ca4d1ea5ee2469c73bc45f8a2dd 136 Gene3D G3DSA:1.10.3760.10 3 136 3.6E-13 T 23-10-2018 TON_0683 6acf2ca4d1ea5ee2469c73bc45f8a2dd 136 SUPERFAMILY SSF101307 7 133 3.66E-33 T 23-10-2018 IPR036681 PgpA-like superfamily GO:0006629|GO:0008962 TON_1151 14f8483b54440dc50fd59c44ab270004 381 SUPERFAMILY SSF55486 192 359 1.17E-9 T 23-10-2018 TON_1151 14f8483b54440dc50fd59c44ab270004 381 Gene3D G3DSA:1.10.390.60 187 381 2.2E-8 T 23-10-2018 TON_1043 c45187d499fb6884dda2bb198fb2a7cc 393 Pfam PF04473 Transglutaminase-like domain 108 254 5.2E-40 T 23-10-2018 IPR007562 Transglutaminase-like domain TON_1768 beca83beb9def6b0a4089b49246acb6c 335 Gene3D G3DSA:3.40.50.300 3 335 2.3E-97 T 23-10-2018 TON_1768 beca83beb9def6b0a4089b49246acb6c 335 SMART SM00382 45 241 8.0E-12 T 23-10-2018 IPR003593 AAA+ ATPase domain TON_1768 beca83beb9def6b0a4089b49246acb6c 335 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 241 331 2.3E-27 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TON_1768 beca83beb9def6b0a4089b49246acb6c 335 ProSitePatterns PS00211 ABC transporters family signature. 164 178 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TON_1768 beca83beb9def6b0a4089b49246acb6c 335 Pfam PF00005 ABC transporter 37 191 7.7E-32 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TON_1768 beca83beb9def6b0a4089b49246acb6c 335 SUPERFAMILY SSF52540 6 263 1.12E-70 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TON_1768 beca83beb9def6b0a4089b49246acb6c 335 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 243 311 1.6E-20 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TON_1392 fa91dd95dca04412bf7ced0e3de46dfb 306 SUPERFAMILY SSF56235 18 299 1.18E-86 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TON_1392 fa91dd95dca04412bf7ced0e3de46dfb 306 Gene3D G3DSA:3.60.20.30 176 304 3.8E-33 T 23-10-2018 TON_1392 fa91dd95dca04412bf7ced0e3de46dfb 306 Pfam PF01112 Asparaginase 3 298 1.2E-92 T 23-10-2018 IPR000246 Peptidase T2, asparaginase 2 GO:0016787 TON_1595 668f20c5545cac631ba43283a1d64e82 152 Gene3D G3DSA:3.30.70.3270 23 152 3.7E-20 T 23-10-2018 TON_1595 668f20c5545cac631ba43283a1d64e82 152 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 46 57 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TON_1595 668f20c5545cac631ba43283a1d64e82 152 Pfam PF13187 4Fe-4S dicluster domain 45 91 1.7E-9 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TON_1595 668f20c5545cac631ba43283a1d64e82 152 SUPERFAMILY SSF54862 27 112 6.98E-21 T 23-10-2018 TON_1595 668f20c5545cac631ba43283a1d64e82 152 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 77 88 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TON_0425 736e519930c1fd36c0de5f1f1e11262b 287 Pfam PF00491 Arginase family 23 279 7.4E-64 T 23-10-2018 IPR006035 Ureohydrolase GO:0046872 TON_0425 736e519930c1fd36c0de5f1f1e11262b 287 Gene3D G3DSA:3.40.800.10 5 285 1.1E-76 T 23-10-2018 TON_0425 736e519930c1fd36c0de5f1f1e11262b 287 TIGRFAM TIGR01230 agmatinase: agmatinase 19 278 4.0E-72 T 23-10-2018 IPR005925 Agmatinase-related KEGG: 00330+3.5.3.11|MetaCyc: PWY-40|MetaCyc: PWY-6305|Reactome: R-HSA-351143 TON_0425 736e519930c1fd36c0de5f1f1e11262b 287 PIRSF PIRSF036979 2 286 1.6E-86 T 23-10-2018 IPR006035 Ureohydrolase GO:0046872 TON_0425 736e519930c1fd36c0de5f1f1e11262b 287 SUPERFAMILY SSF52768 16 284 1.53E-74 T 23-10-2018 IPR023696 Ureohydrolase domain superfamily TON_0857 3e8370dce7325c13af998221742ba7eb 109 Gene3D G3DSA:3.40.1260.10 2 109 9.2E-15 T 23-10-2018 IPR027396 DsrEFH-like TON_0269 c29919ed5a0ca4eebb9d6d1933d417bd 257 Pfam PF04039 Domain related to MnhB subunit of Na+/H+ antiporter 112 236 3.1E-21 T 23-10-2018 IPR007182 Na+/H+ antiporter MnhB subunit-related protein TON_1232 223ca20f8919257ce229517afbe67193 389 TIGRFAM TIGR00260 thrC: threonine synthase 57 379 4.7E-69 T 23-10-2018 IPR004450 Threonine synthase-like TON_1232 223ca20f8919257ce229517afbe67193 389 PIRSF PIRSF038945 42 389 3.1E-90 T 23-10-2018 IPR026260 Threonine synthase, bacterial/archaeal GO:0004795|GO:0009088 KEGG: 00260+4.2.3.1|KEGG: 00750+4.2.3.1 TON_1232 223ca20f8919257ce229517afbe67193 389 Gene3D G3DSA:3.40.50.1100 63 380 3.0E-112 T 23-10-2018 TON_1232 223ca20f8919257ce229517afbe67193 389 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 74 374 3.7E-73 T 23-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme TON_1232 223ca20f8919257ce229517afbe67193 389 Gene3D G3DSA:3.40.50.1100 110 204 3.0E-112 T 23-10-2018 TON_1232 223ca20f8919257ce229517afbe67193 389 SUPERFAMILY SSF53686 4 387 7.99E-95 T 23-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme TON_0674 e199b58b8058140054713057d9835cfa 250 Gene3D G3DSA:3.40.50.300 4 249 9.7E-75 T 23-10-2018 TON_0514 1d8fa35750da19ce8e4df0ee6c5ef7ab 386 Pfam PF04412 Protein of unknown function (DUF521) 1 383 5.5E-148 T 23-10-2018 IPR007506 Aconitase X catalytic domain, putative TON_0510 7ac80869000db1ecc17c35d7bacbaf2e 58 Pfam PF04021 Class III signal peptide 3 25 1.1E-8 T 23-10-2018 IPR007166 Class III signal peptide motif TON_0299 a3f4aafc98ec20c66a99f18212d66774 277 Gene3D G3DSA:2.70.70.10 27 132 2.0E-6 T 23-10-2018 IPR011055 Duplicated hybrid motif TON_0355 d3f8de0ff3fafeef82903d102691ec2e 308 Pfam PF12773 Double zinc ribbon 255 298 8.1E-10 T 23-10-2018 IPR025874 Double zinc ribbon TON_1011 b04aa9c111e7b6e3e5cf2d0bfe3a4320 237 PIRSF PIRSF015736 1 237 5.8E-88 T 23-10-2018 IPR026286 Maleate isomerase/Arylmalonate decarboxylase TON_1011 b04aa9c111e7b6e3e5cf2d0bfe3a4320 237 Pfam PF01177 Asp/Glu/Hydantoin racemase 9 215 4.7E-16 T 23-10-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 TON_1011 b04aa9c111e7b6e3e5cf2d0bfe3a4320 237 Gene3D G3DSA:3.40.50.12500 6 237 2.0E-88 T 23-10-2018 TON_0509 18bfb8f0318a4ef7a6e88e515cdaa5a9 159 SUPERFAMILY SSF48371 6 121 1.36E-13 T 23-10-2018 IPR016024 Armadillo-type fold TON_0509 18bfb8f0318a4ef7a6e88e515cdaa5a9 159 Gene3D G3DSA:1.25.10.10 4 133 5.2E-9 T 23-10-2018 IPR011989 Armadillo-like helical TON_1931 a4e69de0e5aed28fc93c744581c50434 122 SUPERFAMILY SSF46785 14 115 2.05E-24 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TON_1931 a4e69de0e5aed28fc93c744581c50434 122 Gene3D G3DSA:1.10.10.10 10 118 1.5E-28 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TON_1931 a4e69de0e5aed28fc93c744581c50434 122 Pfam PF03551 Transcriptional regulator PadR-like family 26 99 4.0E-23 T 23-10-2018 IPR005149 Transcription regulator PadR, N-terminal TON_0467 8a7cb95d4a08833360d512ed3f463372 35 Pfam PF01161 Phosphatidylethanolamine-binding protein 2 35 1.8E-5 T 23-10-2018 IPR008914 Phosphatidylethanolamine-binding protein TON_0467 8a7cb95d4a08833360d512ed3f463372 35 Gene3D G3DSA:3.90.280.10 1 35 1.5E-10 T 23-10-2018 IPR036610 PEBP-like superfamily TON_0467 8a7cb95d4a08833360d512ed3f463372 35 SUPERFAMILY SSF49777 1 35 6.67E-8 T 23-10-2018 IPR036610 PEBP-like superfamily TON_0772 3f50786eb04679a658592ae0e295ce3d 382 Gene3D G3DSA:3.40.50.150 38 235 2.1E-27 T 23-10-2018 TON_0772 3f50786eb04679a658592ae0e295ce3d 382 SUPERFAMILY SSF53335 55 159 6.27E-20 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TON_0772 3f50786eb04679a658592ae0e295ce3d 382 Pfam PF13847 Methyltransferase domain 85 156 1.4E-8 T 23-10-2018 IPR025714 Methyltransferase domain TON_1696 2cce06c3cb2d951dd608cdf3d1182376 423 SUPERFAMILY SSF53649 2 334 2.91E-40 T 23-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 TON_1696 2cce06c3cb2d951dd608cdf3d1182376 423 Pfam PF00884 Sulfatase 4 329 3.1E-23 T 23-10-2018 IPR000917 Sulfatase, N-terminal GO:0008484 TON_0381 8c9548dbffda9e03ec5ed82e42b12173 128 Pfam PF11469 Ribonuclease III 10 127 3.8E-60 T 23-10-2018 IPR021568 Ribonuclease III, archaeal TON_0381 8c9548dbffda9e03ec5ed82e42b12173 128 SUPERFAMILY SSF69065 7 127 6.8E-51 T 23-10-2018 IPR036389 Ribonuclease III, endonuclease domain superfamily GO:0004525|GO:0006396 TON_0381 8c9548dbffda9e03ec5ed82e42b12173 128 Gene3D G3DSA:1.10.1520.20 2 128 2.4E-47 T 23-10-2018 IPR038133 Ribonuclease III superfamily, archaeal TON_0973 939863289ec9f7615e12edda4d5d1add 171 PIRSF PIRSF016661 1 170 5.7E-49 T 23-10-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 TON_0973 939863289ec9f7615e12edda4d5d1add 171 Pfam PF02632 BioY family 26 166 1.2E-40 T 23-10-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 TON_0973 939863289ec9f7615e12edda4d5d1add 171 Gene3D G3DSA:1.10.1760.20 1 170 4.4E-56 T 23-10-2018 TON_0942 f57f2f9fd9a49c85d5803abe19a8519e 97 Pfam PF11505 Protein of unknown function (DUF3216) 6 96 8.6E-34 T 23-10-2018 IPR023108 Domain of unknown function, DUF3216 TON_0942 f57f2f9fd9a49c85d5803abe19a8519e 97 Gene3D G3DSA:1.20.120.460 2 97 6.4E-37 T 23-10-2018 IPR038317 Pf1176-like superfamily TON_0436 f7168f84d02a084a26e18d86d1ff4ccd 168 Pfam PF06195 Protein of unknown function (DUF996) 22 145 9.4E-26 T 23-10-2018 IPR010397 Protein of unknown function DUF996 TON_1880 68ba6bcf1893b95b4feb4d6066d9a1a0 263 ProDom PD359573 MEMBRANE TRANSMEMBRANE AF2132 PROTEIN 1 168 7.0E-37 T 23-10-2018 TON_0923 aafcebcc5d45301d672cd6b73f8ccfdc 204 SUPERFAMILY SSF51735 2 199 2.08E-50 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TON_0923 aafcebcc5d45301d672cd6b73f8ccfdc 204 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 98 117 5.2E-19 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TON_0923 aafcebcc5d45301d672cd6b73f8ccfdc 204 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 119 136 5.2E-19 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TON_0923 aafcebcc5d45301d672cd6b73f8ccfdc 204 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 163 183 5.2E-19 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TON_0923 aafcebcc5d45301d672cd6b73f8ccfdc 204 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 72 88 5.2E-19 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TON_0923 aafcebcc5d45301d672cd6b73f8ccfdc 204 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 4 198 2.9E-38 T 23-10-2018 TON_0923 aafcebcc5d45301d672cd6b73f8ccfdc 204 Gene3D G3DSA:3.40.50.720 1 199 2.4E-46 T 23-10-2018 TON_1895 e4537e219ca13cb322e7f3fffd09a8e6 245 Pfam PF09874 Predicted membrane protein (DUF2101) 23 228 2.1E-75 T 23-10-2018 IPR018663 Protein of unknown function DUF2101, membrane TON_1587 d7bfc0745c13dd6004375365c84e09d9 148 Pfam PF04039 Domain related to MnhB subunit of Na+/H+ antiporter 8 134 1.8E-26 T 23-10-2018 IPR007182 Na+/H+ antiporter MnhB subunit-related protein TON_0924 5ae0e85a0dd6c18b131d75e298630b38 193 Pfam PF06197 Protein of unknown function (DUF998) 11 181 6.1E-25 T 23-10-2018 IPR009339 Protein of unknown function DUF998 TON_1289 4ba82e3adc1dc8b39f2bf3b5d098f19f 298 Pfam PF01874 ATP:dephospho-CoA triphosphoribosyl transferase 12 286 1.4E-51 T 23-10-2018 IPR002736 Triphosphoribosyl-dephospho-CoA protein GO:0005524|GO:0016310|GO:0046917 MetaCyc: PWY-5796 TON_1289 4ba82e3adc1dc8b39f2bf3b5d098f19f 298 Gene3D G3DSA:1.10.4200.10 25 293 3.1E-60 T 23-10-2018 TON_1910 007f7e75923af08f61d7dc12b9702bbc 98 ProDom PD006052 RIBOSOMAL S24 40S RIBONUCLEOPROTEIN S24E 30S S24 CDNA RIKEN ACETYLATION 11 76 1.0E-28 T 23-10-2018 IPR001976 Ribosomal protein S24e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_1910 007f7e75923af08f61d7dc12b9702bbc 98 Hamap MF_00545 30S ribosomal protein S24e [rps24e]. 1 98 21.158 T 23-10-2018 IPR001976 Ribosomal protein S24e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_1910 007f7e75923af08f61d7dc12b9702bbc 98 ProSitePatterns PS00529 Ribosomal protein S24e signature. 60 82 - T 23-10-2018 IPR018098 Ribosomal S24e conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_1910 007f7e75923af08f61d7dc12b9702bbc 98 Gene3D G3DSA:3.30.70.330 1 98 2.2E-38 T 23-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily TON_1910 007f7e75923af08f61d7dc12b9702bbc 98 SUPERFAMILY SSF54189 1 97 5.4E-32 T 23-10-2018 IPR012678 Ribosomal protein L23/L15e core domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 TON_1910 007f7e75923af08f61d7dc12b9702bbc 98 Pfam PF01282 Ribosomal protein S24e 21 97 7.4E-27 T 23-10-2018 IPR001976 Ribosomal protein S24e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TON_1940 8c9361a34ddce2aae21968dddd30768a 212 Pfam PF04254 Protein of unknown function (DUF432) 51 165 1.3E-26 T 23-10-2018 IPR007366 Protein of unknown function DUF432 TON_1940 8c9361a34ddce2aae21968dddd30768a 212 PIRSF PIRSF019202 1 212 1.6E-44 T 23-10-2018 IPR007366 Protein of unknown function DUF432 TON_0225 22c5a20188fa82b471f1ad840d213de6 111 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 4 105 8.5E-10 T 23-10-2018 IPR003477 mRNA interferase PemK-like GO:0003677 TON_0225 22c5a20188fa82b471f1ad840d213de6 111 Gene3D G3DSA:2.30.30.110 15 111 3.2E-11 T 23-10-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor TON_0225 22c5a20188fa82b471f1ad840d213de6 111 SUPERFAMILY SSF50118 4 110 3.49E-14 T 23-10-2018 TON_1658 7f08cec6c14cc141d8ad218f47e779dc 677 SUPERFAMILY SSF82171 44 326 5.1E-5 T 23-10-2018 TON_1658 7f08cec6c14cc141d8ad218f47e779dc 677 Pfam PF08308 PEGA domain 491 558 1.7E-4 T 23-10-2018 IPR013229 PEGA TON_1658 7f08cec6c14cc141d8ad218f47e779dc 677 Pfam PF08308 PEGA domain 563 628 1.7E-16 T 23-10-2018 IPR013229 PEGA TON_1658 7f08cec6c14cc141d8ad218f47e779dc 677 Pfam PF08308 PEGA domain 431 488 3.5E-9 T 23-10-2018 IPR013229 PEGA TON_1658 7f08cec6c14cc141d8ad218f47e779dc 677 TIGRFAM TIGR04288 CGP_CTERM: CGP-CTERM domain 657 676 1.4E-4 T 23-10-2018 IPR027552 CGP-CTERM domain TON_1702 185bfbc476c236594fb78e89a2d854a0 516 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 344 479 7.3E-24 T 23-10-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain TON_1702 185bfbc476c236594fb78e89a2d854a0 516 Pfam PF01943 Polysaccharide biosynthesis protein 14 282 8.3E-30 T 23-10-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 TON_0201 14a77cb85fe5b2595c714ccd151e04b3 249 Gene3D G3DSA:3.20.20.190 2 249 2.5E-97 T 23-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 TON_0201 14a77cb85fe5b2595c714ccd151e04b3 249 SUPERFAMILY SSF51695 7 215 1.38E-56 T 23-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 TON_0201 14a77cb85fe5b2595c714ccd151e04b3 249 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 13 213 1.2E-31 T 23-10-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 TON_1187 6cdd1aa93709651d0bc670bded98f0e6 246 TIGRFAM TIGR02537 arch_flag_Nterm: archaeal flagellin N-terminal-like domain 6 29 1.1E-5 T 23-10-2018 IPR013373 Flagellin/pilin, N-terminal TON_1187 6cdd1aa93709651d0bc670bded98f0e6 246 Pfam PF01917 Archaebacterial flagellin 8 232 5.6E-50 T 23-10-2018 IPR002774 Flagellin, archaea GO:0005198|GO:0006928 TON_0494 d96e92183af952c3d0115e389201340d 236 Pfam PF04039 Domain related to MnhB subunit of Na+/H+ antiporter 99 222 3.4E-23 T 23-10-2018 IPR007182 Na+/H+ antiporter MnhB subunit-related protein TON_1573 bb68d9abde8ad7f436768b056fbe9f37 342 Gene3D G3DSA:1.20.1080.10 10 279 1.3E-75 T 23-10-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 TON_1573 bb68d9abde8ad7f436768b056fbe9f37 342 Pfam PF01226 Formate/nitrite transporter 15 268 3.3E-71 T 23-10-2018 IPR000292 Formate/nitrite transporter GO:0016020|GO:0022857|GO:0055085 TON_1693 2d03d054d54e37a3c4734034ebb44531 242 Gene3D G3DSA:3.40.50.300 1 242 4.1E-64 T 23-10-2018 TON_0650 9eee9e8c5ab338eaa9b8bcdc17608640 218 SUPERFAMILY SSF56784 4 187 4.84E-15 T 23-10-2018 IPR036412 HAD-like superfamily TON_0650 9eee9e8c5ab338eaa9b8bcdc17608640 218 Gene3D G3DSA:3.40.50.1000 5 134 1.3E-9 T 23-10-2018 IPR023214 HAD superfamily TON_0650 9eee9e8c5ab338eaa9b8bcdc17608640 218 Gene3D G3DSA:1.10.150.520 15 84 1.3E-9 T 23-10-2018 TON_0538 d3396a92a5edb2fc11fd3beed95796f5 329 Gene3D G3DSA:1.20.1080.10 10 274 5.9E-78 T 23-10-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 TON_0538 d3396a92a5edb2fc11fd3beed95796f5 329 Pfam PF01226 Formate/nitrite transporter 14 263 7.5E-72 T 23-10-2018 IPR000292 Formate/nitrite transporter GO:0016020|GO:0022857|GO:0055085 TON_1896 78a65c916a4f711494a04ee29ae300d8 1139 Pfam PF10102 Domain of unknown function (DUF2341) 569 630 3.0E-10 T 23-10-2018 IPR018765 Domain of unknown function DUF2341 TON_1830 306b57e21e78b988b2f62e9e36c7cd04 427 Pfam PF01882 Protein of unknown function DUF58 181 263 9.1E-16 T 23-10-2018 IPR002881 Domain of unknown function DUF58 TON_0922 06f71a76dff023c61a3795399dd52c2d 34 Gene3D G3DSA:3.40.50.720 2 34 1.4E-5 T 23-10-2018 TON_0922 06f71a76dff023c61a3795399dd52c2d 34 SUPERFAMILY SSF51735 4 34 2.5E-6 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily TON_0698 d024cd779b69fccd9532e20a27f159ae 177 SUPERFAMILY SSF55729 2 174 1.46E-42 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase TON_0698 d024cd779b69fccd9532e20a27f159ae 177 Gene3D G3DSA:3.40.630.30 4 173 2.6E-44 T 23-10-2018 TON_0698 d024cd779b69fccd9532e20a27f159ae 177 Pfam PF13302 Acetyltransferase (GNAT) domain 19 149 2.2E-28 T 23-10-2018 IPR000182 GNAT domain TON_0418 7e026525090c138c44aff80f6b78b059 292 TIGRFAM TIGR00374 TIGR00374: TIGR00374 family protein 10 134 8.5E-18 T 23-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD TON_0418 7e026525090c138c44aff80f6b78b059 292 TIGRFAM TIGR00374 TIGR00374: TIGR00374 family protein 180 281 1.1E-19 T 23-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD TON_0418 7e026525090c138c44aff80f6b78b059 292 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 13 273 5.8E-39 T 23-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD TON_1925 487040ba6c87dabb3792034372db05e4 262 Pfam PF13649 Methyltransferase domain 45 144 1.2E-9 T 23-10-2018 TON_1925 487040ba6c87dabb3792034372db05e4 262 SUPERFAMILY SSF53335 16 201 3.04E-20 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TON_1925 487040ba6c87dabb3792034372db05e4 262 Gene3D G3DSA:3.40.50.150 28 166 3.0E-14 T 23-10-2018 TON_1536 dadf59c346991e77b0c3b26b82602826 311 SUPERFAMILY SSF51556 1 310 1.77E-76 T 23-10-2018 IPR032466 Metal-dependent hydrolase TON_1536 dadf59c346991e77b0c3b26b82602826 311 Gene3D G3DSA:3.20.20.140 1 311 3.9E-95 T 23-10-2018 TON_1536 dadf59c346991e77b0c3b26b82602826 311 Pfam PF01244 Membrane dipeptidase (Peptidase family M19) 2 307 1.1E-94 T 23-10-2018 IPR008257 Peptidase M19 GO:0006508|GO:0016805 MetaCyc: PWY-7533|Reactome: R-HSA-2142691|Reactome: R-HSA-5423646 TON_1552 1d2ad85e056bc09ec7094c349a41f60c 406 Pfam PF01384 Phosphate transporter family 22 395 5.7E-110 T 23-10-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 TON_0769 75d3c708b6ec44ce4002601a6ce393f7 273 SUPERFAMILY SSF81345 4 272 4.32E-17 T 23-10-2018 IPR037294 ABC transporter, BtuC-like TON_0769 75d3c708b6ec44ce4002601a6ce393f7 273 Pfam PF00950 ABC 3 transport family 4 266 9.1E-26 T 23-10-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 TON_1686 b107883c35fe5766e6b152d7359b94ca 277 Pfam PF00294 pfkB family carbohydrate kinase 5 272 1.2E-39 T 23-10-2018 IPR011611 Carbohydrate kinase PfkB TON_1686 b107883c35fe5766e6b152d7359b94ca 277 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 230 243 - T 23-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 TON_1686 b107883c35fe5766e6b152d7359b94ca 277 SUPERFAMILY SSF53613 1 273 2.81E-55 T 23-10-2018 IPR029056 Ribokinase-like TON_1686 b107883c35fe5766e6b152d7359b94ca 277 Gene3D G3DSA:3.40.1190.20 1 275 3.2E-58 T 23-10-2018 IPR029056 Ribokinase-like TON_0130 0083d633924ab52356241544f455e4c1 241 Gene3D G3DSA:3.40.50.300 1 240 1.4E-56 T 23-10-2018 TON_0375 aa4d65c4620be7843dd818a20ea41280 244 Gene3D G3DSA:3.40.50.300 14 240 3.3E-61 T 23-10-2018 TON_1424 56801722c86a61fc2136758c9a0282a6 338 Gene3D G3DSA:1.10.3470.10 2 335 1.5E-93 T 23-10-2018 IPR037294 ABC transporter, BtuC-like TON_1424 56801722c86a61fc2136758c9a0282a6 338 SUPERFAMILY SSF81345 4 330 6.93E-78 T 23-10-2018 IPR037294 ABC transporter, BtuC-like TON_1424 56801722c86a61fc2136758c9a0282a6 338 Pfam PF01032 FecCD transport family 13 330 8.9E-86 T 23-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 TON_1111 9a1925adad91544dc4e581b2f237d20b 285 Gene3D G3DSA:3.60.15.10 50 127 2.4E-23 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TON_1111 9a1925adad91544dc4e581b2f237d20b 285 SUPERFAMILY SSF56281 14 285 1.76E-42 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TON_1111 9a1925adad91544dc4e581b2f237d20b 285 Gene3D G3DSA:3.40.50.10890 128 190 2.4E-23 T 23-10-2018 TON_0378 cbc2764cefe4d221c9b36dced4389288 210 Pfam PF09840 Uncharacterized protein conserved in archaea (DUF2067) 10 197 1.4E-52 T 23-10-2018 IPR019202 Protein of unknown function DUF2067 TON_1459 0d87f08663d5fb0eba781ae4b9c1b1a2 181 Gene3D G3DSA:3.40.50.620 42 181 2.2E-7 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TON_1459 0d87f08663d5fb0eba781ae4b9c1b1a2 181 SUPERFAMILY SSF52402 41 175 4.35E-7 T 23-10-2018 TON_0441 f4f502b6f2ddc1f5a997d1463aacb5d1 167 SUPERFAMILY SSF54197 1 158 5.86E-46 T 23-10-2018 IPR036265 HIT-like superfamily TON_0441 f4f502b6f2ddc1f5a997d1463aacb5d1 167 Gene3D G3DSA:3.30.428.10 1 165 6.1E-58 T 23-10-2018 IPR036265 HIT-like superfamily TON_0441 f4f502b6f2ddc1f5a997d1463aacb5d1 167 Pfam PF01230 HIT domain 35 125 1.8E-13 T 23-10-2018 IPR001310 Histidine triad (HIT) protein TON_0841 f3e769652a2b80afe9cfe0e6d41fbe7d 38 Gene3D G3DSA:1.10.10.10 1 38 9.5E-10 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TON_0841 f3e769652a2b80afe9cfe0e6d41fbe7d 38 SUPERFAMILY SSF46785 1 36 1.79E-6 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TON_1087 72dc249de8e3b666a55572ba01d887c9 393 Gene3D G3DSA:1.25.40.10 213 385 1.3E-6 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TON_1087 72dc249de8e3b666a55572ba01d887c9 393 SUPERFAMILY SSF48452 11 318 7.59E-6 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TON_1087 72dc249de8e3b666a55572ba01d887c9 393 SMART SM00028 289 322 6.4 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TON_1087 72dc249de8e3b666a55572ba01d887c9 393 SMART SM00028 127 160 18.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TON_0452 3788a793f363aad46c1519e2f84aae08 92 Gene3D G3DSA:3.30.310.50 7 92 6.1E-25 T 23-10-2018 TON_0452 3788a793f363aad46c1519e2f84aae08 92 Pfam PF09341 Transcription factor Pcc1 20 90 6.6E-12 T 23-10-2018 IPR015419 CTAG/Pcc1 family TON_0550 ff725d83a69e420bcb07dd7bcbd7c090 275 Pfam PF01040 UbiA prenyltransferase family 5 250 1.8E-24 T 23-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 TON_1350 80d6f90bc1181599ceeefe9743b6ab0a 99 Pfam PF09946 Predicted membrane protein (DUF2178) 5 63 2.0E-5 T 23-10-2018 IPR019235 Protein of unknown function DUF2178, transmembrane TON_0992 3d605dc46c246cc2dc3e8ce6f864009e 254 Pfam PF01061 ABC-2 type transporter 3 216 4.4E-44 T 23-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 TON_0992 3d605dc46c246cc2dc3e8ce6f864009e 254 PIRSF PIRSF006648 1 253 3.5E-71 T 23-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 TON_0992 3d605dc46c246cc2dc3e8ce6f864009e 254 PRINTS PR00164 ABC-2 type transport system membrane protein signature 175 194 8.9E-16 T 23-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 TON_0992 3d605dc46c246cc2dc3e8ce6f864009e 254 PRINTS PR00164 ABC-2 type transport system membrane protein signature 195 214 8.9E-16 T 23-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 TON_0992 3d605dc46c246cc2dc3e8ce6f864009e 254 PRINTS PR00164 ABC-2 type transport system membrane protein signature 138 162 8.9E-16 T 23-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 TON_0992 3d605dc46c246cc2dc3e8ce6f864009e 254 PRINTS PR00164 ABC-2 type transport system membrane protein signature 101 126 8.9E-16 T 23-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 TON_0992 3d605dc46c246cc2dc3e8ce6f864009e 254 PRINTS PR00164 ABC-2 type transport system membrane protein signature 22 43 8.9E-16 T 23-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 TON_0992 3d605dc46c246cc2dc3e8ce6f864009e 254 TIGRFAM TIGR01247 drrB: daunorubicin resistance ABC transporter membrane protein 10 248 1.7E-119 T 23-10-2018 IPR005942 Daunorubicin resistance ABC transporter membrane protein TON_1901 45f6d9c09d34a2cc8607fe76dd346b05 211 Pfam PF04021 Class III signal peptide 6 31 6.5E-8 T 23-10-2018 IPR007166 Class III signal peptide motif TON_1524 73d3fd1eb50610d5926ecdc69a699b33 224 TIGRFAM TIGR00659 TIGR00659: TIGR00659 family protein 6 223 4.7E-80 T 23-10-2018 IPR005261 Conserved hypothetical protein CHP00659 TON_1524 73d3fd1eb50610d5926ecdc69a699b33 224 Pfam PF04172 LrgB-like family 9 221 9.4E-72 T 23-10-2018 IPR007300 CidB/LrgB family TON_0762 c5cdf2961ea46c5bb9685fec53adb628 415 PIRSF PIRSF018863 1 415 9.0E-198 T 23-10-2018 IPR014496 Uncharacterised conserved protein UCP018863 TON_0762 c5cdf2961ea46c5bb9685fec53adb628 415 Pfam PF04409 Protein of unknown function (DUF530) 5 255 4.8E-23 T 23-10-2018 IPR007503 Protein of unknown function DUF530 TON_0837 9a3ccf33a0b06d148f51055f1c4fd27f 111 SUPERFAMILY SSF158791 52 107 9.94E-5 T 23-10-2018 TON_0497 234dfc5a4a7e84def910e0d90179dfa4 84 Pfam PF04066 Multiple resistance and pH regulation protein F (MrpF / PhaF) 30 81 3.7E-18 T 23-10-2018 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 TON_1433 c0b0542d67ad0fa3eddc20fa4ec74a34 80 Pfam PF13396 Phospholipase_D-nuclease N-terminal 24 65 4.5E-8 T 23-10-2018 IPR027379 Cardiolipin synthase N-terminal TON_1460 b317297dd639accca607fd4b752463f9 638 Gene3D G3DSA:3.30.230.10 32 227 3.3E-28 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TON_1460 b317297dd639accca607fd4b752463f9 638 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 69 179 1.0E-12 T 23-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 TON_1460 b317297dd639accca607fd4b752463f9 638 SUPERFAMILY SSF54211 49 230 2.66E-25 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TON_1875 27e536cd2159318c9c0b8a4a53bc3bb5 1252 Pfam PF02514 CobN/Magnesium Chelatase 92 1194 0.0 T 23-10-2018 IPR003672 CobN/magnesium chelatase GO:0009058 TON_0531 4c34d10dbafaf474d9adebe4b13cd468 445 Pfam PF01458 Uncharacterized protein family (UPF0051) 194 417 2.3E-53 T 23-10-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 TON_0531 4c34d10dbafaf474d9adebe4b13cd468 445 SUPERFAMILY SSF101960 18 441 8.37E-102 T 23-10-2018 IPR037284 SUF system FeS cluster assembly, SufBD superfamily TON_1378 ac74feead8c03b73aa60e87bbca73988 367 Gene3D G3DSA:1.10.443.10 157 332 3.2E-12 T 23-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 TON_1378 ac74feead8c03b73aa60e87bbca73988 367 SUPERFAMILY SSF56349 39 317 2.18E-19 T 23-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 TON_1378 ac74feead8c03b73aa60e87bbca73988 367 Gene3D G3DSA:1.10.150.130 35 123 2.8E-5 T 23-10-2018 IPR010998 Integrase/recombinase, N-terminal TON_1470 f369d5006ebdd23f9d7da1fae6b9304a 388 Gene3D G3DSA:1.20.1530.20 2 381 6.8E-85 T 23-10-2018 IPR038770 Sodium/solute symporter superfamily TON_1470 f369d5006ebdd23f9d7da1fae6b9304a 388 Pfam PF00999 Sodium/hydrogen exchanger family 11 372 2.2E-60 T 23-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 TON_1181 6a5f3b58922a9031c676564a7592486c 159 SUPERFAMILY SSF49373 51 129 6.02E-5 T 23-10-2018 IPR008964 Invasin/intimin cell-adhesion fragments TON_1181 6a5f3b58922a9031c676564a7592486c 159 Pfam PF01917 Archaebacterial flagellin 5 156 4.4E-23 T 23-10-2018 IPR002774 Flagellin, archaea GO:0005198|GO:0006928 TON_0386 c53688f1ce36eddd34622b69d2c78e56 272 Gene3D G3DSA:3.20.20.20 1 270 3.8E-92 T 23-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TON_0386 c53688f1ce36eddd34622b69d2c78e56 272 SUPERFAMILY SSF51717 5 269 2.62E-82 T 23-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TON_0386 c53688f1ce36eddd34622b69d2c78e56 272 Pfam PF00809 Pterin binding enzyme 14 252 2.1E-63 T 23-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TON_0386 c53688f1ce36eddd34622b69d2c78e56 272 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 13 266 1.3E-72 T 23-10-2018 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 TON_1711 686a52ec03f56bd5d4b12257434492b7 391 Pfam PF00999 Sodium/hydrogen exchanger family 9 382 5.9E-56 T 23-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 TON_1711 686a52ec03f56bd5d4b12257434492b7 391 Gene3D G3DSA:1.20.1530.20 1 391 1.7E-76 T 23-10-2018 IPR038770 Sodium/solute symporter superfamily TON_1946 879769bf5df78ded5ef928f5b29ff920 56 Hamap MF_00751 Preprotein translocase subunit SecG [secG]. 1 51 14.969 T 23-10-2018 IPR023531 Preprotein translocase subunit SecG TON_1946 879769bf5df78ded5ef928f5b29ff920 56 Pfam PF03911 Sec61beta family 11 51 3.2E-15 T 23-10-2018 IPR016482 Protein transport protein SecG/Sec61-beta/Sbh Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TON_1482 b889025b681c9773061512058d3bb1df 331 Gene3D G3DSA:3.40.50.970 92 321 2.0E-68 T 23-10-2018 TON_1482 b889025b681c9773061512058d3bb1df 331 SUPERFAMILY SSF52518 12 318 2.19E-76 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold TON_1482 b889025b681c9773061512058d3bb1df 331 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 57 218 5.7E-26 T 23-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 TON_1200 712bcb0f5708cc6bf718dacb3b247afc 241 Pfam PF04509 CheC-like family 14 46 1.8E-4 T 23-10-2018 IPR007597 CheC-like protein GO:0016787 TON_1200 712bcb0f5708cc6bf718dacb3b247afc 241 Gene3D G3DSA:3.40.1550.10 7 203 4.6E-36 T 23-10-2018 IPR028976 CheC-like superfamily TON_1200 712bcb0f5708cc6bf718dacb3b247afc 241 Pfam PF13690 Chemotaxis phosphatase CheX 67 143 1.2E-8 T 23-10-2018 IPR028051 Chemotaxis phosphatase CheX-like domain TON_1200 712bcb0f5708cc6bf718dacb3b247afc 241 SUPERFAMILY SSF103039 7 201 4.27E-33 T 23-10-2018 IPR028976 CheC-like superfamily TON_0955 2a8f81209a0c70a67d07b57aa26335ee 203 PIRSF PIRSF015877 1 199 1.1E-68 T 23-10-2018 IPR012041 Uncharacterised conserved protein UCP015877, zinc finger-containing TON_0955 2a8f81209a0c70a67d07b57aa26335ee 203 Pfam PF01873 Domain found in IF2B/IF5 2 34 5.1E-5 T 23-10-2018 IPR002735 Translation initiation factor IF2/IF5 GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 TON_0955 2a8f81209a0c70a67d07b57aa26335ee 203 SUPERFAMILY SSF75689 4 38 3.27E-5 T 23-10-2018 IPR016190 Translation initiation factor IF2/IF5, zinc-binding GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 TON_1923 a67889b6db78851af9f4192e396ab963 264 SUPERFAMILY SSF56317 1 262 1.05E-74 T 23-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily TON_1923 a67889b6db78851af9f4192e396ab963 264 Gene3D G3DSA:3.60.110.10 1 263 1.4E-104 T 23-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily TON_1923 a67889b6db78851af9f4192e396ab963 264 Pfam PF00795 Carbon-nitrogen hydrolase 2 244 2.6E-59 T 23-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 TON_0978 d0769e607aafc5eff0144ff37ec9b719 263 Pfam PF01889 Membrane protein of unknown function DUF63 6 262 8.4E-75 T 23-10-2018 IPR002749 Protein of unknown function DUF63 TON_1408 ebb526288a151895184e0a338d4e6286 471 Gene3D G3DSA:2.40.380.10 374 471 7.5E-11 T 23-10-2018 IPR035930 FomD-like superfamily TON_1408 ebb526288a151895184e0a338d4e6286 471 SUPERFAMILY SSF159234 318 469 3.66E-31 T 23-10-2018 IPR035930 FomD-like superfamily TON_1408 ebb526288a151895184e0a338d4e6286 471 Hamap MF_01910 RNA-binding protein AU-1 [aubA]. 7 471 34.567 T 23-10-2018 IPR016730 RNA-binding AU-1 GO:0003723 TON_1408 ebb526288a151895184e0a338d4e6286 471 PIRSF PIRSF018644 5 471 2.5E-193 T 23-10-2018 IPR016730 RNA-binding AU-1 GO:0003723 TON_1408 ebb526288a151895184e0a338d4e6286 471 Pfam PF10150 Ribonuclease E/G family 152 264 2.8E-12 T 23-10-2018 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 TON_1408 ebb526288a151895184e0a338d4e6286 471 Pfam PF04167 Protein of unknown function (DUF402) 379 443 1.7E-13 T 23-10-2018 IPR007295 Domain of unknown function DUF402 TON_1258 9ae11009cda824ac0aa898549c96610d 135 Pfam PF08617 Kinase binding protein CGI-121 42 105 1.2E-4 T 23-10-2018 IPR013926 CGI121/TPRKB Reactome: R-HSA-6782315 TON_1258 9ae11009cda824ac0aa898549c96610d 135 SUPERFAMILY SSF143870 14 127 2.09E-23 T 23-10-2018 IPR036504 CGI121/TPRKB superfamily Reactome: R-HSA-6782315 TON_1258 9ae11009cda824ac0aa898549c96610d 135 Gene3D G3DSA:3.30.2380.10 5 135 1.0E-46 T 23-10-2018 IPR036504 CGI121/TPRKB superfamily Reactome: R-HSA-6782315 TON_0427 9e6fc3c2280b11f870b4c5b31a9214e2 459 SUPERFAMILY SSF161070 13 391 1.83E-7 T 23-10-2018 IPR037272 Sodium:neurotransmitter symporter superfamily GO:0005328 TON_0921 25cc937f4323dd554e0b1eae723c6353 135 SUPERFAMILY SSF53146 1 113 1.7E-30 T 23-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily TON_0921 25cc937f4323dd554e0b1eae723c6353 135 Gene3D G3DSA:3.30.420.130 1 122 3.1E-31 T 23-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily TON_0921 25cc937f4323dd554e0b1eae723c6353 135 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 13 106 5.6E-22 T 23-10-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis TON_0678 2092d891f2609c9961bc32756bf58b6b 320 SUPERFAMILY SSF53383 13 317 9.32E-57 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TON_0678 2092d891f2609c9961bc32756bf58b6b 320 Pfam PF00155 Aminotransferase class I and II 28 315 4.4E-37 T 23-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 TON_0678 2092d891f2609c9961bc32756bf58b6b 320 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 188 197 - T 23-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 TON_0678 2092d891f2609c9961bc32756bf58b6b 320 Gene3D G3DSA:3.40.640.10 30 233 1.0E-70 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TON_0678 2092d891f2609c9961bc32756bf58b6b 320 Gene3D G3DSA:3.90.1150.10 19 315 1.0E-70 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TON_0337 df487ba142a30a4c46bc7d079bc7a266 251 SUPERFAMILY SSF55307 159 246 1.19E-9 T 23-10-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 TON_0337 df487ba142a30a4c46bc7d079bc7a266 251 Gene3D G3DSA:3.40.50.1440 117 249 3.2E-5 T 23-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 TON_1307 c0aaf675086e62632d8e4ca480ea1de4 135 PIRSF PIRSF006606 3 132 2.2E-45 T 23-10-2018 IPR007154 Protein of unknown function DUF356 TON_1307 c0aaf675086e62632d8e4ca480ea1de4 135 Pfam PF04009 Protein of unknown function (DUF356) 5 110 8.9E-35 T 23-10-2018 IPR007154 Protein of unknown function DUF356 TON_0490 246642f9bb654e568cb96f79dfa4cbf1 309 Pfam PF00146 NADH dehydrogenase 8 306 2.2E-53 T 23-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_1539 c0718ca81a215d845aac8b914bba8b36 282 Pfam PF13649 Methyltransferase domain 130 231 3.3E-9 T 23-10-2018 TON_1539 c0718ca81a215d845aac8b914bba8b36 282 Gene3D G3DSA:3.40.50.150 112 281 5.0E-27 T 23-10-2018 TON_1539 c0718ca81a215d845aac8b914bba8b36 282 SUPERFAMILY SSF53335 90 263 4.62E-37 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TON_0272 4d4636bc08f0d07baa933681c72c2f75 94 Pfam PF04066 Multiple resistance and pH regulation protein F (MrpF / PhaF) 36 87 1.9E-10 T 23-10-2018 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 TON_0259 42644c638805b9f8b15014b442adb014 341 TIGRFAM TIGR00816 tdt: C4-dicarboxylate transporter/malic acid transport protein 8 334 1.7E-88 T 23-10-2018 IPR011552 Tellurite resistance protein TehA/malic acid transport protein GO:0016021 TON_0259 42644c638805b9f8b15014b442adb014 341 Pfam PF03595 Voltage-dependent anion channel 8 328 3.6E-69 T 23-10-2018 IPR004695 Voltage-dependent anion channel GO:0016021|GO:0055085 TON_0259 42644c638805b9f8b15014b442adb014 341 Gene3D G3DSA:1.50.10.150 4 336 1.6E-41 T 23-10-2018 IPR038665 Voltage-dependent anion channel superfamily TON_0571 ece3c39fd737b9ba6170192786a091d4 254 Pfam PF01925 Sulfite exporter TauE/SafE 8 244 1.9E-58 T 23-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 TON_0233 ea208b33cf6f935a42a4de124e6b3a51 193 Pfam PF03956 Lysine exporter LysO 9 190 7.6E-58 T 23-10-2018 IPR005642 Lysine exporter LysO TON_0233 ea208b33cf6f935a42a4de124e6b3a51 193 ProDom PD022789 MEMBRANE SURFACE PRECURSOR SIGNAL PROTEIN YBJE TRANSMEMBRANE INNER PREDICTED STY0934 24 193 6.0E-45 T 23-10-2018 IPR005642 Lysine exporter LysO TON_1865 5407160600210f1d9b668779894113a9 59 Pfam PF07754 Domain of unknown function (DUF1610) 10 33 2.5E-14 T 23-10-2018 IPR011668 Domain of unknown function DUF1610 TON_1489 8810fbf930e8c5107c4dd1d47f013125 197 PIRSF PIRSF004897 1 165 3.5E-46 T 23-10-2018 IPR014424 Uncharacterised conserved protein UCP004897, ACT- type TON_0631 b5bf0c3cbcfb069ada6829ba994382bf 226 Pfam PF13349 Putative adhesin 10 120 3.0E-7 T 23-10-2018 IPR025164 Putative adhesin TON_1588 6e48c748c210c7a611b8bd98e0821daa 119 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 6 116 4.4E-27 T 23-10-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like TON_0439 bd1ce1c2c4dea85396d34599c2d21ac4 543 Pfam PF03553 Na+/H+ antiporter family 167 496 4.3E-75 T 23-10-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 TON_0017 748263051dac734f8e0340534c40c5e7 348 Pfam PF01594 AI-2E family transporter 12 322 4.1E-33 T 23-10-2018 IPR002549 Transmembrane protein TqsA-like TON_1007 d5661b9bbbdafb46703d0dabfdc91af1 184 Pfam PF06197 Protein of unknown function (DUF998) 13 175 2.4E-13 T 23-10-2018 IPR009339 Protein of unknown function DUF998 TON_1029 bdaad858e7c4e34147fc6f5345e64e33 134 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 13 125 3.4E-22 T 23-10-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like TON_1680 17d4ee1caadf5bce38fdf626b5436197 164 PIRSF PIRSF019115 1 164 6.7E-65 T 23-10-2018 IPR019217 Protein of unknown function DUF2118 TON_1680 17d4ee1caadf5bce38fdf626b5436197 164 Pfam PF09891 Uncharacterized protein conserved in archaea (DUF2118) 3 163 1.2E-51 T 23-10-2018 IPR019217 Protein of unknown function DUF2118 TON_1680 17d4ee1caadf5bce38fdf626b5436197 164 Gene3D G3DSA:2.40.50.100 97 163 2.2E-31 T 23-10-2018 TON_1827 4ba38b32e6fa673f82797bff8a5f768e 198 Pfam PF12389 Camelysin metallo-endopeptidase 7 198 4.0E-6 T 23-10-2018 IPR022121 Peptidase M73, camelysin TON_0693 e2f97c4e05e774fa33a9555af4f3d268 379 Pfam PF05763 Protein of unknown function (DUF835) 248 377 5.3E-30 T 23-10-2018 IPR008553 Domain of unknown function DUF835 TON_0913 1caf72a8ede9dd472c9b6c47fe47a44a 480 Pfam PF10102 Domain of unknown function (DUF2341) 187 262 8.7E-16 T 23-10-2018 IPR018765 Domain of unknown function DUF2341 TON_0127 41bc3632d2d2900f5f6f5fada424057f 433 Gene3D G3DSA:1.25.40.10 3 175 6.6E-16 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TON_0127 41bc3632d2d2900f5f6f5fada424057f 433 Gene3D G3DSA:1.25.40.10 268 408 3.6E-10 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TON_0274 c2e427aa07888d510581c5908a55f393 266 Gene3D G3DSA:3.40.50.12280 2 168 1.5E-40 T 23-10-2018 TON_0274 c2e427aa07888d510581c5908a55f393 266 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 17 147 1.1E-24 T 23-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_0274 c2e427aa07888d510581c5908a55f393 266 SUPERFAMILY SSF56770 5 160 4.06E-43 T 23-10-2018 TON_0493 b2c7d93939d1ff7a17d8ce61a6cf53c4 114 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 5 111 7.2E-32 T 23-10-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like TON_0477 f3944c8956a7920ca15ed6b33265c7c6 84 SUPERFAMILY SSF140683 15 77 7.19E-17 T 23-10-2018 IPR038062 ScdA-like, N-terminal domain superfamily TON_0477 f3944c8956a7920ca15ed6b33265c7c6 84 Gene3D G3DSA:1.10.3910.10 8 78 1.7E-19 T 23-10-2018 IPR038062 ScdA-like, N-terminal domain superfamily TON_0477 f3944c8956a7920ca15ed6b33265c7c6 84 Pfam PF08984 Domain of unknown function (DUF1858) 15 70 7.9E-17 T 23-10-2018 IPR015077 Domain of unknown function DUF1858 TON_0558 3aacdbc65fa84ff60defeacf579dad35 189 Hamap MF_00801 Endonuclease V [nfi]. 6 189 25.763 T 23-10-2018 IPR007581 Endonuclease V GO:0004519|GO:0006281 TON_0558 3aacdbc65fa84ff60defeacf579dad35 189 Pfam PF04493 Endonuclease V 17 139 5.0E-33 T 23-10-2018 IPR007581 Endonuclease V GO:0004519|GO:0006281 TON_0558 3aacdbc65fa84ff60defeacf579dad35 189 Pfam PF04493 Endonuclease V 144 182 7.3E-5 T 23-10-2018 IPR007581 Endonuclease V GO:0004519|GO:0006281 TON_0558 3aacdbc65fa84ff60defeacf579dad35 189 Gene3D G3DSA:3.30.2170.10 144 188 4.0E-7 T 23-10-2018 TON_0558 3aacdbc65fa84ff60defeacf579dad35 189 Gene3D G3DSA:3.30.2170.10 4 143 1.4E-36 T 23-10-2018 TON_1041 0889f3290c0a050c960c78be27447f02 248 Pfam PF05763 Protein of unknown function (DUF835) 125 243 8.5E-34 T 23-10-2018 IPR008553 Domain of unknown function DUF835 TON_1290 207a9d72bb6efba6476c98538fabb578 93 SUPERFAMILY SSF111057 1 92 2.22E-31 T 23-10-2018 IPR036216 Hypothetical protein UCP004604 superfamily TON_1290 207a9d72bb6efba6476c98538fabb578 93 Gene3D G3DSA:3.30.2320.10 1 93 3.1E-25 T 23-10-2018 TON_1290 207a9d72bb6efba6476c98538fabb578 93 PIRSF PIRSF004604 1 93 8.3E-22 T 23-10-2018 IPR014418 Uncharacterised conserved protein UCP004604 TON_1290 207a9d72bb6efba6476c98538fabb578 93 Pfam PF08967 Domain of unknown function (DUF1884) 2 91 3.6E-38 T 23-10-2018 IPR014418 Uncharacterised conserved protein UCP004604 TON_1290 207a9d72bb6efba6476c98538fabb578 93 ProDom PD029791 ORF 3'REGION GAP PF1875 PF0899 PH1831 B PHS036 2 92 2.0E-21 T 23-10-2018 IPR014418 Uncharacterised conserved protein UCP004604 TON_0474 31abcfe070b6d5cea807b7ed15069341 271 SUPERFAMILY SSF100950 12 121 2.2E-6 T 23-10-2018 IPR037171 NagB/RpiA transferase-like TON_1186 2c1687ce5c04857195627d1c96aa0753 221 Pfam PF01917 Archaebacterial flagellin 4 207 3.1E-43 T 23-10-2018 IPR002774 Flagellin, archaea GO:0005198|GO:0006928 TON_1186 2c1687ce5c04857195627d1c96aa0753 221 TIGRFAM TIGR02537 arch_flag_Nterm: archaeal flagellin N-terminal-like domain 2 25 1.0E-5 T 23-10-2018 IPR013373 Flagellin/pilin, N-terminal TON_1367 885c7552d30bb9d5d42959e5909b3216 121 Pfam PF10066 Uncharacterized conserved protein (DUF2304) 4 107 4.7E-26 T 23-10-2018 IPR019277 Protein of unknown function DUF2304 TON_1963 7a4650a8571218745ef60c676c247462 377 Pfam PF04123 Domain of unknown function (DUF373) 6 346 4.9E-100 T 23-10-2018 IPR007254 Protein of unknown function DUF373 TON_0491 50be890722a5fdee5540e6cc2cdc23d1 620 Pfam PF00361 Proton-conducting membrane transporter 119 424 6.5E-60 T 23-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_1824 67ad6a19cbb8400f6fb8b412d027af6f 1937 Pfam PF13620 Carboxypeptidase regulatory-like domain 1635 1727 5.4E-8 T 23-10-2018 TON_0818 b1765b70fc6e583f8ce8c961bfe03b65 138 Pfam PF12646 Domain of unknown function (DUF3783) 60 115 1.3E-16 T 23-10-2018 IPR016621 Uncharacterised conserved protein UCP014543 TON_0818 b1765b70fc6e583f8ce8c961bfe03b65 138 PIRSF PIRSF014543 2 125 2.1E-41 T 23-10-2018 IPR016621 Uncharacterised conserved protein UCP014543 TON_0363 3e4eac9f0a871e5a4bc8763ea6ebac6d 493 Pfam PF02386 Cation transport protein 56 479 1.4E-66 T 23-10-2018 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 TON_0363 3e4eac9f0a871e5a4bc8763ea6ebac6d 493 TIGRFAM TIGR00933 2a38: potassium uptake protein, TrkH family 96 469 3.8E-110 T 23-10-2018 IPR004772 TrkH potassium transport family GO:0015379|GO:0016021|GO:0071805 TON_0788 9a970b5df9d4d8d549a51f327d0201a3 66 TIGRFAM TIGR04140 chp_AF_0576: TIGR04140 family protein 1 66 1.6E-31 T 23-10-2018 IPR026486 Uncharacterised protein AF_0576 TON_1703 c4e1fd5a7f07f257964437f95db9f616 247 Pfam PF01925 Sulfite exporter TauE/SafE 8 241 1.0E-41 T 23-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 TON_1540 c57544f21447ded9fb0dd262037d4a99 465 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 299 394 4.4E-8 T 23-10-2018 IPR007404 LexA-binding, inner membrane-associated putative hydrolase TON_1579 bac32179c6e75ef5fd1e23b8abed86f0 161 Pfam PF01899 Na+/H+ ion antiporter subunit 9 159 9.3E-40 T 23-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 TON_1579 bac32179c6e75ef5fd1e23b8abed86f0 161 PIRSF PIRSF019239 1 161 1.6E-42 T 23-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 TON_1575 741e0deebd878e0d1bdfd4b18abd035c 119 Pfam PF03334 Na+/H+ antiporter subunit 12 98 1.0E-15 T 23-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 TON_1575 741e0deebd878e0d1bdfd4b18abd035c 119 TIGRFAM TIGR01300 CPA3_mnhG_phaG: monovalent cation/proton antiporter, MnhG/PhaG subunit 11 112 9.7E-27 T 23-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 TON_1517 13fc4eefd304d6fef4846fc56cf06db3 552 Pfam PF03553 Na+/H+ antiporter family 156 506 1.5E-65 T 23-10-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 TON_1521 c0de26e541490c3d174b4a502a462986 101 Gene3D G3DSA:3.30.70.1750 4 99 3.2E-29 T 23-10-2018 TON_1521 c0de26e541490c3d174b4a502a462986 101 Pfam PF11491 Protein of unknown function (DUF3213) 14 96 4.2E-35 T 23-10-2018 IPR021583 Protein of unknown function DUF3213 TON_1356 aa7c03085d9abfd0b0052ef14ef8da91 586 Gene3D G3DSA:1.50.10.20 319 481 4.9E-8 T 23-10-2018 TON_1356 aa7c03085d9abfd0b0052ef14ef8da91 586 Gene3D G3DSA:1.50.10.20 37 188 1.5E-12 T 23-10-2018 TON_1356 aa7c03085d9abfd0b0052ef14ef8da91 586 SUPERFAMILY SSF48239 32 481 4.32E-23 T 23-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid TON_0360 2859906f8e82b85346ee03d9552f16e3 369 Pfam PF05763 Protein of unknown function (DUF835) 242 366 6.2E-35 T 23-10-2018 IPR008553 Domain of unknown function DUF835 TON_0251 ffb69a1705395d15d78e23c8c3d010b0 233 Pfam PF01963 TraB family 9 224 2.6E-15 T 23-10-2018 IPR002816 Pheromone shutdown, TraB TON_1654 4eee8205a06d539738f9528ddcff916b 319 Pfam PF05763 Protein of unknown function (DUF835) 214 318 6.7E-30 T 23-10-2018 IPR008553 Domain of unknown function DUF835 TON_1578 63426992364b4628ff98285eb0d9c262 134 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 11 121 8.1E-21 T 23-10-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like TON_0496 ad2046f680fe156190c04251646dbc60 136 Pfam PF03334 Na+/H+ antiporter subunit 11 95 1.9E-24 T 23-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 TON_0496 ad2046f680fe156190c04251646dbc60 136 TIGRFAM TIGR01300 CPA3_mnhG_phaG: monovalent cation/proton antiporter, MnhG/PhaG subunit 10 110 2.9E-28 T 23-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 TON_0728 c7ecb68fa3e1c94a1a6bbc41902f9adf 235 Pfam PF14358 Domain of unknown function (DUF4405) 13 76 3.4E-17 T 23-10-2018 IPR025517 Domain of unknown function DUF4405 TON_0270 24da666542c404f41bc685ed560eb08b 84 Pfam PF13244 Domain of unknown function (DUF4040) 16 80 2.5E-14 T 23-10-2018 IPR025383 Domain of unknown function DUF4040 TON_1781 baf9e666b943cf2e0a3ed8779ee68faf 375 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 5 365 5.2E-39 T 23-10-2018 IPR002823 Protein of unknown function DUF112, transmembrane TON_1584 f8f9ace2772529c3fcb5ad16cea426b4 123 Pfam PF03334 Na+/H+ antiporter subunit 11 100 2.6E-23 T 23-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 TON_1584 f8f9ace2772529c3fcb5ad16cea426b4 123 TIGRFAM TIGR01300 CPA3_mnhG_phaG: monovalent cation/proton antiporter, MnhG/PhaG subunit 11 114 1.1E-34 T 23-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 TON_0744 0f14672d3b4f52c625ef62ef2956db54 59 SUPERFAMILY SSF47113 6 59 1.35E-6 T 23-10-2018 IPR009072 Histone-fold GO:0046982 TON_1328 9c8e6cefc6fbe2bed7971a3603e87f5d 133 Pfam PF04039 Domain related to MnhB subunit of Na+/H+ antiporter 6 120 7.7E-26 T 23-10-2018 IPR007182 Na+/H+ antiporter MnhB subunit-related protein TON_1389 278df3fbbea0abd899ef85e03105c895 163 Gene3D G3DSA:1.25.40.10 2 163 1.5E-5 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TON_0268 f9c8649dd9d0f2420115ed03cbb9e4a1 130 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 13 125 5.4E-24 T 23-10-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like TON_0163 2ceb1964b9c1df7d02b7eb552e3721be 387 Gene3D G3DSA:3.40.50.300 1 183 5.8E-14 T 23-10-2018 TON_1868 64ddf56e0f5f1f00c048f74b07af3ca8 247 SUPERFAMILY SSF81301 30 183 5.89E-5 T 23-10-2018 TON_1260 b17409eb268e574fcd88494d537043d4 87 Pfam PF01169 Uncharacterized protein family UPF0016 5 79 6.5E-23 T 23-10-2018 IPR001727 Gdt1 family TON_0330 b79c6d8a008d42cacefec44149f1b199 176 Pfam PF04434 SWIM zinc finger 46 69 4.2E-6 T 23-10-2018 IPR007527 Zinc finger, SWIM-type GO:0008270 TON_1736 3753d5d6de5451789d5498cf7cb0be46 173 Pfam PF03692 Putative zinc- or iron-chelating domain 16 127 7.9E-15 T 23-10-2018 IPR005358 Putative zinc- or iron-chelating domain containing protein TON_0495 1929bb0fee1bb582c76883d8686eeb9f 94 Pfam PF13244 Domain of unknown function (DUF4040) 13 79 2.6E-19 T 23-10-2018 IPR025383 Domain of unknown function DUF4040 TON_1782 9ba179c1f9d58dc4b3bd4fa334d20eba 102 Gene3D G3DSA:3.30.720.70 1 102 3.6E-40 T 23-10-2018 TON_1708 9cabbcc4c0c37119c785136cc60c50fb 75 SUPERFAMILY SSF47598 7 49 7.23E-7 T 23-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 TON_1330 798b8a41a74dc49b9d14f87a6ccdb440 76 Pfam PF13244 Domain of unknown function (DUF4040) 12 74 2.6E-11 T 23-10-2018 IPR025383 Domain of unknown function DUF4040 TON_0971 47c4f69aa695ee56924c2ca7410b7e35 121 SUPERFAMILY SSF52317 30 107 2.75E-5 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like TON_0689 80c58fa5b773e2662e463eaf376df208 195 Pfam PF01955 Adenosylcobinamide amidohydrolase 10 182 7.5E-46 T 23-10-2018 IPR002808 Adenosylcobinamide amidohydrolase, CbiZ TON_1287 e0e6fe2f7ad446593b0dec70a1b63f72 137 Pfam PF04024 PspC domain 1 56 1.6E-17 T 23-10-2018 IPR007168 Phage shock protein, PspC, N-terminal TON_1382 af34842eb3ee892dca520c14327a6dba 394 Pfam PF09545 AccI restriction endonuclease 28 390 1.2E-71 T 23-10-2018 IPR019054 Restriction endonuclease, type II, AccI TON_1028 28e829f59e16663c021af739bf4723e0 256 Pfam PF04039 Domain related to MnhB subunit of Na+/H+ antiporter 109 233 1.7E-22 T 23-10-2018 IPR007182 Na+/H+ antiporter MnhB subunit-related protein TON_0005 806a2822044780cd0920c9b9be916267 489 Pfam PF05124 S-layer like family, C-terminal region 402 488 3.4E-9 T 23-10-2018 IPR022651 S-layer protein, C-terminal TON_1728 e1dae3bdca812c90796564dbea11032c 98 Pfam PF06156 Initiation control protein YabA 8 70 5.6E-7 T 23-10-2018 IPR010377 Initiation control protein YabA GO:0006260 TON_1191 072f013422f457067bbf096a9f87c55a 109 Pfam PF07381 Winged helix DNA-binding domain (DUF1495) 10 98 1.8E-35 T 23-10-2018 IPR010863 Protein of unknown function DUF1495 TON_1191 072f013422f457067bbf096a9f87c55a 109 SUPERFAMILY SSF46785 18 108 3.33E-9 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TON_0358 ba06fa31dd6c14b81fd97d3015a64cd2 271 Pfam PF02673 Bacitracin resistance protein BacA 11 255 9.9E-28 T 23-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 TON_0552 79f2420d9a23b454b8131727a48691e5 246 Gene3D G3DSA:3.40.50.300 3 240 4.4E-76 T 23-10-2018 TON_0051 1a97a0797e03dc7f43ba32c97a7619aa 107 Gene3D G3DSA:2.40.30.10 19 107 3.4E-19 T 23-10-2018 TON_0051 1a97a0797e03dc7f43ba32c97a7619aa 107 SUPERFAMILY SSF50447 26 106 5.2E-11 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily TON_1411 5d9bb10a00862d383e418bd26f5db61b 315 Pfam PF05763 Protein of unknown function (DUF835) 116 250 2.2E-37 T 23-10-2018 IPR008553 Domain of unknown function DUF835 TON_1566 24e25e49a29353d0566db24a8a8a03c2 404 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 256 275 7.8E-9 T 23-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_1566 24e25e49a29353d0566db24a8a8a03c2 404 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 102 126 7.8E-9 T 23-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_1566 24e25e49a29353d0566db24a8a8a03c2 404 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 165 189 7.8E-9 T 23-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_1566 24e25e49a29353d0566db24a8a8a03c2 404 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 308 334 7.8E-9 T 23-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_1566 24e25e49a29353d0566db24a8a8a03c2 404 Pfam PF00361 Proton-conducting membrane transporter 65 347 8.3E-46 T 23-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TON_1706 75073e51242bb6b14479079dbd9ae70e 311 SUPERFAMILY SSF64182 3 310 9.68E-30 T 23-10-2018 IPR038763 DHH phosphoesterase superfamily TON_1585 4de7d31a03c0e3626c17584ef27b2c0b 88 Pfam PF13244 Domain of unknown function (DUF4040) 18 82 6.6E-17 T 23-10-2018 IPR025383 Domain of unknown function DUF4040 TON_0512 389ea7ffc05f4c64c9ec2e6efd5a2b42 416 Pfam PF02163 Peptidase family M50 302 347 1.6E-7 T 23-10-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 TON_0808 b377ab5f90fd839b1e25c720f263dddc 155 Pfam PF06695 Putative small multi-drug export protein 17 143 3.0E-29 T 23-10-2018 IPR009577 Putative small multi-drug export TON_1121 e2fe6fdc1e3ca1f38bcf7a1bb17f081c 71 Gene3D G3DSA:2.30.30.100 2 71 2.8E-30 T 23-10-2018 TON_1121 e2fe6fdc1e3ca1f38bcf7a1bb17f081c 71 SUPERFAMILY SSF50182 6 71 2.45E-28 T 23-10-2018 IPR010920 LSM domain superfamily TON_0667 aba6bfebf81d858558e7384166f612bf 64 Gene3D G3DSA:3.60.15.10 1 62 3.8E-13 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TON_1681 5ef97c6e2a61dddaa6387ae135dc8efe 286 Pfam PF13559 Domain of unknown function (DUF4129) 210 276 1.2E-6 T 23-10-2018 IPR025403 Domain of unknown function DUF4129 TON_1574 07ca517569c58f04bcb14a6859883669 93 Pfam PF04066 Multiple resistance and pH regulation protein F (MrpF / PhaF) 35 86 3.7E-12 T 23-10-2018 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 TON_1523 6b807260ebcdc5417bd19c8986929b87 117 Pfam PF03788 LrgA family 13 104 2.8E-29 T 23-10-2018 IPR005538 LrgA/CidA family GO:0016021