locus-tag	class	description
A3L08_00030	ENOG4105K4P	CoA-binding domain protein
A3L08_00055	ENOG4108RMN	UPF0128 protein
A3L08_00075	ENOG4107104	thymidine kinase
A3L08_00080	ENOG4105DT1	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate
A3L08_00125	ENOG4105CJ1	ABC, transporter
A3L08_00135	ENOG4108Y5D	Inherit from COG: cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
A3L08_00150	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
A3L08_00160	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
A3L08_00170	ENOG4107QJE	Chromosome Partitioning Protein
A3L08_00175	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
A3L08_00190	ENOG4105CHM	Aminotransferase
A3L08_00235	ENOG4105VZ8	Transcriptional regulator
A3L08_00245	ENOG4105CJ1	ABC, transporter
A3L08_00280	ENOG4108JQ7	(ABC) transporter
A3L08_00290	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
A3L08_00295	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
A3L08_00300	ENOG4105DEF	Extracellular solute-binding protein, family 5
A3L08_00330	ENOG4105CDJ	oxidoreductase FAD NAD(P)-binding domain protein
A3L08_00345	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
A3L08_00360	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
A3L08_00365	ENOG4105SC1	monovalent cation H antiporter subunit E
A3L08_00370	ENOG41080TA	Multiple resistance and ph regulation protein f
A3L08_00375	ENOG4105KJM	monovalent cation h antiporter subunit g
A3L08_00400	ENOG4108JPZ	Monovalent cation H antiporter subunit D
A3L08_00425	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
A3L08_00450	ENOG4107WCI	zn-dependent hydrolase of the beta-lactamase fold-like protein
A3L08_00455	ENOG4105CK7	Sodium proline symporter
A3L08_00525	ENOG4105CHU	acetyl-coa acetyltransferase
A3L08_00530	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
A3L08_00550	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
A3L08_00555	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
A3L08_00560	ENOG4108Z86	Glutamine amidotransferase
A3L08_00570	ENOG4108UKZ	OsmC family
A3L08_00575	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
A3L08_00605	ENOG4107R7Y	intracellular protease Pfpi family
A3L08_00615	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
A3L08_00630	ENOG4105CK7	Sodium proline symporter
A3L08_00645	ENOG4105C6X	Major Facilitator
A3L08_00665	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
A3L08_00670	ENOG41080HI	glycine oxidase
A3L08_00695	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
A3L08_00700	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
A3L08_00720	ENOG4108JVH	Protein of unknown function DUF43
A3L08_00730	ENOG4105VG1	fes assembly suf system protein
A3L08_00735	ENOG41084T3	4fe-4S ferredoxin iron-sulfur binding domain-containing protein
A3L08_00760	ENOG4105BZ8	glutamate synthase
A3L08_00765	ENOG4105CDJ	oxidoreductase FAD NAD(P)-binding domain protein
A3L08_00805	ENOG4105D0M	Protease HtpX homolog
A3L08_00810	ENOG4108UK2	deaminase
A3L08_00820	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
A3L08_00835	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
A3L08_00840	ENOG4105DJB	Major Facilitator Superfamily
A3L08_00855	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
A3L08_00865	ENOG4105D44	asparaginase
A3L08_00870	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
A3L08_00890	ENOG4105DK7	lysyl-tRNA synthetase
A3L08_00930	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
A3L08_00945	ENOG4105EHU	Circadian clock protein KaiC
A3L08_00960	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
A3L08_00975	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
A3L08_00980	ENOG4105D1H	recombination factor protein RarA
A3L08_00985	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
A3L08_01000	ENOG4108ESU	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane (By similarity)
A3L08_01005	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
A3L08_01010	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
A3L08_01020	ENOG4105C7B	Threonine dehydratase
A3L08_01030	ENOG4105NBF	ammecr1 domain protein
A3L08_01040	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
A3L08_01045	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
A3L08_01080	ENOG4105CXT	aspartate transcarbamylase
A3L08_01085	ENOG4108R9M	Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity)
A3L08_01100	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
A3L08_01120	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
A3L08_01205	ENOG4108J9M	Transporter
A3L08_01220	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
A3L08_01235	ENOG4107GFK	fumarate
A3L08_01245	ENOG4108JQ1	Dehydrogenase
A3L08_01255	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
A3L08_01260	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
A3L08_01265	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
A3L08_01295	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
A3L08_01300	ENOG4105CJ3	phosphate transporter
A3L08_01315	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
A3L08_01320	ENOG4105DDK	oxidoreductase, beta subunit
A3L08_01330	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
A3L08_01335	ENOG4105DDK	oxidoreductase, beta subunit
A3L08_01340	ENOG4105D1F	ATP-binding protein
A3L08_01365	ENOG4105CJ1	ABC, transporter
A3L08_01380	ENOG4108RVA	ribokinase
A3L08_01390	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
A3L08_01400	ENOG4108UUC	Protein of unknown function DUF99
A3L08_01410	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
A3L08_01425	ENOG4107UX3	phosphatidylethanolamine N-methyltransferase
A3L08_01455	ENOG4105EWK	phytoene
A3L08_01465	ENOG4107NFR	Fructose-1,6-bisphosphatase
A3L08_01480	ENOG4108VVK	transcriptional Regulator, AsnC
A3L08_01485	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
A3L08_01500	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
A3L08_01520	ENOG4107S6Z	Na H antiporter
A3L08_01525	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
A3L08_01535	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
A3L08_01550	ENOG4105VAW	lrga family
A3L08_01555	ENOG41067MG	lrgb family
A3L08_01575	ENOG4107W7X	Aldolase
A3L08_01585	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
A3L08_01635	ENOG4107S5Z	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity)
A3L08_01640	ENOG4105VFR	signal peptidase
A3L08_01655	ENOG4108IGT	Dipeptidase
A3L08_01665	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
A3L08_01710	ENOG4105CJ3	phosphate transporter
A3L08_01725	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
A3L08_01730	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
A3L08_01735	ENOG4105SC1	monovalent cation H antiporter subunit E
A3L08_01745	ENOG4105KJM	monovalent cation h antiporter subunit g
A3L08_01770	ENOG4108JPZ	Monovalent cation H antiporter subunit D
A3L08_01780	ENOG4105C47	NADH ubiquinone oxidoreductase 20 kda subunit
A3L08_01785	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
A3L08_01790	ENOG4108HM5	NADH-ubiquinone oxidoreductase chain 49kDa
A3L08_01795	ENOG4107TDF	Formate hydrogenlyase subunit 4
A3L08_01840	ENOG4105C3M	thioredoxin reductase
A3L08_01845	ENOG4108JPW	Aminotransferase
A3L08_01875	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
A3L08_01895	ENOG4108VVK	transcriptional Regulator, AsnC
A3L08_01900	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
A3L08_01920	ENOG4108ZAF	Molybdopterin
A3L08_01930	ENOG4105D06	uba thif-type nad fad binding protein
A3L08_01955	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
A3L08_01965	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
A3L08_01975	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
A3L08_02030	ENOG4105EYW	Ion transport protein
A3L08_02040	ENOG4105CYV	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures (By similarity)
A3L08_02055	ENOG4105CB1	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
A3L08_02060	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
A3L08_02065	ENOG4105D1H	recombination factor protein RarA
A3L08_02090	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
A3L08_02110	ENOG41082SX	arsR family transcriptional regulator
A3L08_02130	ENOG4105ERH	Fumarylacetoacetate hydrolase
A3L08_02145	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
A3L08_02150	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
A3L08_02160	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
A3L08_02195	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
A3L08_02215	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
A3L08_02235	ENOG4105CTD	carboxy-peptidase
A3L08_02245	ENOG4107SCK	Monooxygenase
A3L08_02250	ENOG4108KN7	Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity)
A3L08_02290	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
A3L08_02295	ENOG4105C0H	protease
A3L08_02300	ENOG4105K64	Glycosyl transferase, family 2
A3L08_02305	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
A3L08_02310	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
A3L08_02315	ENOG4107Y2G	Glycosyl transferase (Group 1
A3L08_02335	ENOG4107TSN	permease
A3L08_02340	ENOG4107T1U	Catalyzes the synthesis of activated sulfate (By similarity)
A3L08_02355	ENOG4107RIQ	Sulfate adenylate transferase
A3L08_02380	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
A3L08_02405	ENOG4105C6W	4-alpha-glucanotransferase (EC 2.4.1.25)
A3L08_02415	ENOG4107R56	PP-loop domain protein
A3L08_02420	ENOG4105DZ0	fad dependent oxidoreductase
A3L08_02425	ENOG4105W87	Cbs domain
A3L08_02430	ENOG4107RWR	Sodium hydrogen exchanger
A3L08_02435	ENOG4107RWR	Sodium hydrogen exchanger
A3L08_02445	ENOG4105CUT	histidyl-tRNA synthetase
A3L08_02450	ENOG4108JPW	Aminotransferase
A3L08_02455	ENOG4105BZG	amino acid carrier protein
A3L08_02465	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
A3L08_02495	ENOG4107XF7	NGG1p interacting factor 3 protein, NIF3
A3L08_02540	ENOG4105EHU	Circadian clock protein KaiC
A3L08_02550	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
A3L08_02555	ENOG4108JIS	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
A3L08_02560	ENOG4105C3D	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
A3L08_02565	ENOG4105C1A	potassium transporter peripheral membrane
A3L08_02585	ENOG4105K4G	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
A3L08_02600	ENOG4108JIQ	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit (By similarity)
A3L08_02615	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
A3L08_02630	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
A3L08_02645	ENOG4105DF0	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity)
A3L08_02650	ENOG4105CD3	dihydroorotase
A3L08_02665	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
A3L08_02670	ENOG4105C3U	ABC transporter
A3L08_02675	ENOG4108JQ7	(ABC) transporter
A3L08_02685	ENOG4105C4K	Nad synthetase
A3L08_02695	ENOG4105C5F	glutamine synthetase
A3L08_02735	ENOG4105EHU	Circadian clock protein KaiC
A3L08_02755	ENOG4105DR4	Methyltransferase
A3L08_02760	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
A3L08_02770	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
A3L08_02780	ENOG4105EPD	Oligopeptide transporter, Opt family
A3L08_02785	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
A3L08_02790	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
A3L08_02810	ENOG4105EG2	ABC transporter, permease
A3L08_02820	ENOG4107FKK	extracellular solute-binding protein family 1
A3L08_02830	ENOG4108NGU	Transcriptional regulator
A3L08_02835	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
A3L08_02875	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
A3L08_02880	ENOG4108K16	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
A3L08_02895	ENOG4105BZ8	glutamate synthase
A3L08_02900	ENOG4105WE2	aldehyde ferredoxin oxidoreductase
A3L08_02905	ENOG4108G2S	Thiamine biosynthesis protein thiS
A3L08_02925	ENOG4105M7V	2'-5' rna ligase
A3L08_02945	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
A3L08_02955	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
A3L08_02965	ENOG4108IAJ	Nad-dependent epimerase dehydratase
A3L08_02990	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
A3L08_03035	ENOG4107V9E	glucose-1-phosphate thymidylyltransferase
A3L08_03045	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
A3L08_03100	ENOG4107UU3	sucrose-phosphate synthase (EC 2.4.1.14)
A3L08_03110	ENOG4105CKK	Glycosyl transferase, family 2
A3L08_03120	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
A3L08_03190	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
A3L08_03195	ENOG4108IYU	L-aspartate oxidase
A3L08_03205	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
A3L08_03210	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
A3L08_03215	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
A3L08_03220	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
A3L08_03235	ENOG4105C8V	SAICAR synthetase
A3L08_03240	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
A3L08_03245	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
A3L08_03250	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
A3L08_03255	ENOG4107QNG	Phosphoribosylglycinamide synthetase
A3L08_03270	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
A3L08_03275	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
A3L08_03285	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
A3L08_03290	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
A3L08_03355	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
A3L08_03385	ENOG4105F0N	pyrophosphate phospho-hydrolase
A3L08_03445	ENOG4105IIU	Aminopeptidase
A3L08_03525	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
A3L08_03530	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
A3L08_03535	ENOG4105D64	Mechanosensitive ion channel
A3L08_03570	ENOG4105EM7	Selenocysteine-specific translation elongation factor
A3L08_03590	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
A3L08_03595	ENOG410825M	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
A3L08_03605	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
A3L08_03655	ENOG4105C7N	Xanthine uracil vitamin C permease
A3L08_03665	ENOG4108N53	binding-protein-dependent transport systems inner membrane Component
A3L08_03700	ENOG4105NBF	ammecr1 domain protein
A3L08_03705	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
A3L08_03720	ENOG4105CQ2	DNA polymerase
A3L08_03755	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
A3L08_03770	ENOG4105HDK	L-asparaginase
A3L08_03775	ENOG4105D94	Major Facilitator Superfamily
A3L08_03780	ENOG4105VUN	Transcriptional regulator
A3L08_03785	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
A3L08_03795	ENOG4108RWI	nicotinamidase
A3L08_03815	ENOG4105DQU	oxidoreductase, subunit beta
A3L08_03855	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
A3L08_03860	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
A3L08_03865	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
A3L08_03895	ENOG4105C2X	Arabinose 5-phosphate isomerase
A3L08_03900	ENOG4105D9Q	decarboxylase (Beta subunit)
A3L08_03905	ENOG4107QSA	Oxaloacetate decarboxylase
A3L08_03915	ENOG4105D8K	carboxyl transferase
A3L08_03925	ENOG4105CDU	Replicative dna helicase
A3L08_03950	ENOG4105CKX	Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP
A3L08_03995	ENOG4107QIZ	NADH dehydrogenase
A3L08_04010	ENOG4105C5S	asparaginyl-tRNA synthetase
A3L08_04020	ENOG4105C5R	Aminotransferase
A3L08_04045	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
A3L08_04055	ENOG4105KZR	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
A3L08_04060	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
A3L08_04065	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
A3L08_04070	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
A3L08_04075	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
A3L08_04080	ENOG41082SA	50s ribosomal protein l29
A3L08_04085	ENOG4108ZJT	translation initiation factor, Sui1
A3L08_04095	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
A3L08_04100	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
A3L08_04105	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
A3L08_04115	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
A3L08_04125	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
A3L08_04130	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
A3L08_04145	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
A3L08_04150	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
A3L08_04155	ENOG4105VPB	50S ribosomal protein L30
A3L08_04160	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
A3L08_04185	ENOG4108Z4J	Cytidine monophosphate kinase
A3L08_04200	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
A3L08_04205	ENOG4107Y49	methyltransferase
A3L08_04215	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
A3L08_04220	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
A3L08_04225	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
A3L08_04245	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
A3L08_04250	ENOG4108UJD	30S ribosomal protein S9
A3L08_04275	ENOG4105CE9	30S ribosomal protein S2
A3L08_04310	ENOG4108YXU	transcriptional regulator AsnC family
A3L08_04320	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
A3L08_04335	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
A3L08_04350	ENOG4105CB1	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
A3L08_04370	ENOG4108I5U	Uridine phosphorylase
A3L08_04375	ENOG4108IYI	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
A3L08_04380	ENOG41074MP	UPF0103 Mediator of ErbB2-driven cell motility-containing protein
A3L08_04385	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
A3L08_04410	ENOG4105EHU	Circadian clock protein KaiC
A3L08_04415	ENOG4106UJV	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
A3L08_04430	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
A3L08_04430	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
A3L08_04440	ENOG4105C8T	Leucyl-tRNA synthetase
A3L08_04450	ENOG4105DC7	peptidase M24
A3L08_04470	ENOG4108JEB	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
A3L08_04490	ENOG4105MRR	Transcriptional regulator (By similarity)
A3L08_04510	ENOG4108YZA	Nitrogen regulatory protein pii
A3L08_04520	ENOG4105C8J	)-transporter
A3L08_04525	ENOG4105D82	Glutamate dehydrogenase
A3L08_04535	ENOG4105KPK	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation (By similarity)
A3L08_04540	ENOG4105CY0	Metallo-Beta-Lactamase
A3L08_04555	ENOG4105E66	phosphoriboisomerase A
A3L08_04570	ENOG4105CH2	amidohydrolase
A3L08_04580	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
A3L08_04595	ENOG4105C5S	asparaginyl-tRNA synthetase
A3L08_04615	ENOG4105U0R	haloacid dehalogenase-like hydrolase
A3L08_04625	ENOG4108VA3	3-hexulose-6-phosphate synthase
A3L08_04650	ENOG4106K5Q	Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication (By similarity)
A3L08_04670	ENOG4105CD5	CoA-binding domain protein
A3L08_04725	ENOG4108IYC	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
A3L08_04735	ENOG4108JU3	Alkyl hydroperoxide reductase
A3L08_04750	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
A3L08_04755	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
A3L08_04770	ENOG4108T9Q	UPF0278 protein
A3L08_04800	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
A3L08_04815	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
A3L08_04820	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
A3L08_04840	ENOG4105DHP	deoxycytidine triphosphate deaminase
A3L08_04870	ENOG4105CX6	glutaminyL-tRNA synthetase
A3L08_04880	ENOG4107R76	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
A3L08_04885	ENOG4105C0M	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity)
A3L08_04900	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
A3L08_04930	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
A3L08_04935	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
A3L08_04945	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
A3L08_05000	ENOG4107QK8	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
A3L08_05005	ENOG4107RGW	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
A3L08_05035	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
A3L08_05045	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
A3L08_05065	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
A3L08_05070	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
A3L08_05115	ENOG4105CHM	Aminotransferase
A3L08_05140	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
A3L08_05155	ENOG4105CFT	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import (By similarity)
A3L08_05170	ENOG4108JJB	ABC transporter
A3L08_05190	ENOG4108Y83	glucose-6-phosphate isomerase
A3L08_05210	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
A3L08_05220	ENOG4105PGM	cation diffusion facilitator family transporter
A3L08_05235	ENOG4105D6J	arsenicaL-resistance protein
A3L08_05250	ENOG4105D6J	arsenicaL-resistance protein
A3L08_05295	ENOG4105WE2	aldehyde ferredoxin oxidoreductase
A3L08_05335	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
A3L08_05345	ENOG4105CQS	hydrogenase expression formation protein HypD
A3L08_05355	ENOG4105C45	hydrogenase expression formation protein (HypE)
A3L08_05385	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
A3L08_05400	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
A3L08_05420	ENOG4105UQX	Mate efflux family protein
A3L08_05430	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
A3L08_05455	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
A3L08_05475	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
A3L08_05485	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
A3L08_05490	ENOG4107V9E	glucose-1-phosphate thymidylyltransferase
A3L08_05500	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
A3L08_05510	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
A3L08_05515	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
A3L08_05520	ENOG4108JJB	ABC transporter
A3L08_05540	ENOG4105CN9	Peptidase m42 family protein
A3L08_05555	ENOG4108Z0R	Transferase
A3L08_05560	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
A3L08_05575	ENOG4105C22	threonyL-tRNA synthetase
A3L08_05620	ENOG4105F4G	Membrane
A3L08_05655	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
A3L08_05660	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
A3L08_05665	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
A3L08_05675	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
A3L08_05680	ENOG4105CPQ	Dehydrogenase
A3L08_05700	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
A3L08_05705	ENOG4105HDK	L-asparaginase
A3L08_05735	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
A3L08_05745	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
A3L08_05775	ENOG4105CG5	Glycosyl transferase (Group 1
A3L08_05785	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
A3L08_05805	ENOG4107RWR	Sodium hydrogen exchanger
A3L08_05850	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
A3L08_05855	ENOG4105DBV	ornithine carbamoyltransferase
A3L08_05860	ENOG41087GE	Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity)
A3L08_05865	ENOG4107S6Z	Na H antiporter
A3L08_05875	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
A3L08_05890	ENOG4105E3H	phosphoglycerate mutase
A3L08_05895	ENOG4105CIH	Imidazole acetol-phosphate transaminase
A3L08_05900	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
A3L08_05920	ENOG4108UHF	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
A3L08_05925	ENOG41085AN	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
A3L08_05940	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
A3L08_05945	ENOG4108K7V	UPF0284 protein
A3L08_05955	ENOG4108W8B	Beta-lactamase domain protein
A3L08_05960	ENOG4105CV8	reductase
A3L08_05975	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
A3L08_05995	ENOG4105BZR	domain protein
A3L08_06065	ENOG4107WPW	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
A3L08_06105	ENOG4105CHR	reductase
A3L08_06110	ENOG4108V1U	phospholipid-binding protein
A3L08_06150	ENOG4108JPW	Aminotransferase
A3L08_06170	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
A3L08_06175	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
A3L08_06180	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
A3L08_06185	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
A3L08_06190	ENOG4108IZQ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
A3L08_06195	ENOG4108JPZ	Monovalent cation H antiporter subunit D
A3L08_06200	ENOG4108JPZ	Monovalent cation H antiporter subunit D
A3L08_06205	ENOG4105MKQ	Monovalent cation H antiporter subunit C
A3L08_06210	ENOG4105D65	subunit l
A3L08_06220	ENOG4105KJM	monovalent cation h antiporter subunit g
A3L08_06225	ENOG410684G	monovalent cation H antiporter subunit F
A3L08_06230	ENOG4105SC1	monovalent cation H antiporter subunit E
A3L08_06240	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
A3L08_06260	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
A3L08_06265	ENOG4108IJ1	Dehydrogenase
A3L08_06285	ENOG4105C75	arginyL-tRNA synthetase
A3L08_06290	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
A3L08_06380	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
A3L08_06400	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
A3L08_06410	ENOG4108VVK	transcriptional Regulator, AsnC
A3L08_06430	ENOG4105KME	endoribonuclease L-psp
A3L08_06440	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
A3L08_06445	ENOG4105C3K	feS assembly ATPase SufC
A3L08_06450	ENOG4105DIW	FeS assembly protein SUFB
A3L08_06490	ENOG4107SHJ	sulfite reductase subunit b
A3L08_06500	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
A3L08_06505	ENOG4105QAX	Iron-sulfur
A3L08_06510	ENOG4105D65	subunit l
A3L08_06515	ENOG4108JPZ	Monovalent cation H antiporter subunit D
A3L08_06520	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
A3L08_06525	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
A3L08_06530	ENOG4108RG7	formate hydrogenlyase complex iron-sulfur subunit
A3L08_06535	ENOG4105C47	NADH ubiquinone oxidoreductase 20 kda subunit
A3L08_06565	ENOG4108ZE9	Monovalent cation H antiporter subunit C
A3L08_06575	ENOG4108JPZ	Monovalent cation H antiporter subunit D
A3L08_06590	ENOG4108393	oxidoreductase Fe-S subunit
A3L08_06605	ENOG4105E3S	small subunit
A3L08_06615	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
A3L08_06635	ENOG4105C1A	potassium transporter peripheral membrane
A3L08_06655	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
A3L08_06665	ENOG4105DZH	s-adenosylmethionine synthetase (EC 2.5.1.6)
A3L08_06675	ENOG4105Q33	Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency
A3L08_06685	ENOG4105CHM	Aminotransferase
A3L08_06695	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
A3L08_06700	ENOG4105C5I	Dehydrogenase
A3L08_06705	ENOG4105CN9	Peptidase m42 family protein
A3L08_06745	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
A3L08_06760	ENOG4105DQU	oxidoreductase, subunit beta
A3L08_06765	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
A3L08_06775	ENOG4105DQU	oxidoreductase, subunit beta
A3L08_06780	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
A3L08_06795	ENOG4108439	Cell division protein mraZ
A3L08_06805	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
A3L08_06815	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
A3L08_06825	ENOG4105DIH	basic membrane
A3L08_06830	ENOG4108JQ9	ABC transporter
A3L08_06835	ENOG4105UIB	(ABC) transporter
A3L08_06860	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
A3L08_06865	ENOG4105C8N	cysteinyl-tRNA synthetase
A3L08_06870	ENOG4108YZY	peptidylprolyl cis-trans isomerase
A3L08_06890	ENOG4105DWF	phosphomethylpyrimidine kinase
A3L08_06895	ENOG4105IQJ	Involved in biosynthesis of the thiamine precursor thiazole (By similarity)
A3L08_06900	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
A3L08_06905	ENOG4105C8V	SAICAR synthetase
A3L08_06920	ENOG4108IA2	Sodium pantothenate symporter
A3L08_06940	ENOG4108JQ7	(ABC) transporter
A3L08_06945	ENOG4105C3U	ABC transporter
A3L08_06950	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
A3L08_06955	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
A3L08_06980	ENOG4105CS2	ec 3.2.1.21
A3L08_07005	ENOG4105EMU	Dehydrogenase
A3L08_07015	ENOG4105EHU	Circadian clock protein KaiC
A3L08_07020	ENOG4107QRT	dEAD DEAH box helicase
A3L08_07030	ENOG4107QJZ	Glycosyl transferase, family 2
A3L08_07090	ENOG4105DER	m42 family
A3L08_07120	ENOG4108WBT	adenosyltransferase
A3L08_07130	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
A3L08_07135	ENOG4105CEV	competence damage-inducible protein
A3L08_07150	ENOG4105VZ9	UPF0235 protein
A3L08_07165	ENOG4105VXP	Protein of unknown function DUF86
A3L08_07170	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
A3L08_07190	ENOG4105UQX	Mate efflux family protein
A3L08_07200	ENOG4108K3F	N(2),N(2)-dimethylguanosine tRNA methyltransferase
A3L08_07215	ENOG4105DC7	peptidase M24
A3L08_07230	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
A3L08_07270	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
A3L08_07285	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
A3L08_07305	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
A3L08_07315	ENOG4105FDK	ABC transporter
A3L08_07335	ENOG41065SU	Two-component system sensor kinase
A3L08_07355	ENOG4105FBQ	ATPase associated with various cellular activities aaa_5
A3L08_07365	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
A3L08_07370	ENOG4105DCI	Phosphohydrolase
A3L08_07375	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
A3L08_07380	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
A3L08_07385	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
A3L08_07405	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
A3L08_07440	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
A3L08_07445	ENOG4108IJ8	ABC transporter
A3L08_07470	ENOG4105FDK	ABC transporter
A3L08_07485	ENOG4108I5C	dEAD DEAH box helicase
A3L08_07490	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
A3L08_07515	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
A3L08_07520	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
A3L08_07540	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
A3L08_07555	ENOG4108T0W	nitrous oxide maturation protein NosY
A3L08_07570	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
A3L08_07580	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
A3L08_07585	ENOG4105G0J	serine threonine protein kinase
A3L08_07600	ENOG4105D0M	Protease HtpX homolog
A3L08_07605	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
A3L08_07610	ENOG4105E0R	Deoxyhypusine synthase
A3L08_07620	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
A3L08_07640	ENOG4105DCI	Phosphohydrolase
A3L08_07650	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
A3L08_07655	ENOG4105EPU	Molybdenum cofactor synthesis domain protein
A3L08_07660	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
A3L08_07715	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
A3L08_07720	ENOG4105E4P	ATPase (AAA
A3L08_07765	ENOG4105CG9	aspartate racemase
A3L08_07770	ENOG4105D7N	magnesium and cobalt transport protein CorA
A3L08_07780	ENOG4105C3G	gtp-binding protein
A3L08_07795	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
A3L08_07810	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
A3L08_07825	ENOG4105WMR	Protein CrcB homolog
A3L08_07830	ENOG4105KJJ	Uncharacterized ACR, COG1993
A3L08_07840	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
A3L08_07900	ENOG4107XGZ	Hydrolase
A3L08_07910	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
A3L08_07920	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
A3L08_07960	ENOG4108J2R	molybdopterin oxidoreductase
A3L08_07965	ENOG4105D3R	alkyl hydroperoxide reductase
A3L08_07975	ENOG4105CNW	domain protein
A3L08_07980	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
A3L08_07985	ENOG4105EHG	Permease protein
A3L08_07990	ENOG4105S10	periplasmic binding protein
A3L08_08000	ENOG4105MRR	Transcriptional regulator (By similarity)
A3L08_08015	ENOG4105C59	p-type ATPase
A3L08_08050	ENOG4105FBQ	ATPase associated with various cellular activities aaa_5
A3L08_08090	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
A3L08_08105	ENOG4105CS2	ec 3.2.1.21
A3L08_08115	ENOG4105DK0	Indole-3-glycerol phosphate synthase
A3L08_08120	ENOG4105F4P	)-transporter
A3L08_08125	ENOG41090A1	ferritin
A3L08_08130	ENOG4107Y03	Nitroreductase
A3L08_08135	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
A3L08_08145	ENOG4105D2S	major facilitator superfamily
A3L08_08155	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
A3L08_08185	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
A3L08_08195	ENOG4105EQ7	Binding-protein-dependent transport systems, inner membrane component
A3L08_08200	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
A3L08_08205	ENOG4107STW	synthase
A3L08_08210	ENOG4107Y7Q	pfkb domain protein
A3L08_08240	ENOG4108RAC	Rubrerythrin
A3L08_08245	ENOG4105VCQ	rubredoxin
A3L08_08250	ENOG4108YZ8	Superoxide reductase
A3L08_08310	ENOG4107R8N	Glycosyl transferase, family 2
A3L08_08355	ENOG4105CIG	ABC transporter
A3L08_08395	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
A3L08_08405	ENOG4105CK2	sodium dicarboxylate symporter
A3L08_08410	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
A3L08_08420	ENOG41061GT	Aldolase
A3L08_08425	ENOG4107QSA	Oxaloacetate decarboxylase
A3L08_08430	ENOG4105D22	carbon starvation protein
A3L08_08455	ENOG4105E5G	Alpha beta hydrolase fold
A3L08_08460	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
A3L08_08465	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
A3L08_08475	ENOG4105D1F	ATP-binding protein
A3L08_08500	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
A3L08_08505	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
A3L08_08545	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
A3L08_08560	ENOG4105VYW	UPF0251 protein
A3L08_08565	ENOG4105C83	adenylosuccinate lyase
A3L08_08590	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
A3L08_08635	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
A3L08_08640	ENOG4107QRT	dEAD DEAH box helicase
A3L08_08645	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
A3L08_08660	ENOG4105FBQ	ATPase associated with various cellular activities aaa_5
A3L08_08670	ENOG4105E7A	Glutamine amidotransferase
A3L08_08680	ENOG41065RQ	ADP-ribosylation crystallin J1
A3L08_08685	ENOG41065RQ	ADP-ribosylation crystallin J1
A3L08_08715	ENOG4105C5X	domain protein
A3L08_08730	ENOG4105F8V	Hydrolase, tatD family
A3L08_08755	ENOG4107WZZ	SMC domain protein
A3L08_08755	ENOG4107WZZ	SMC domain protein
A3L08_08770	ENOG4105C5I	Dehydrogenase
A3L08_08775	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
A3L08_08780	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
A3L08_08785	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
A3L08_08800	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
A3L08_08830	ENOG4105C11	sulfate adenylyltransferase), subunit 2
A3L08_08845	ENOG4107SYB	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
A3L08_08850	ENOG4105C5S	asparaginyl-tRNA synthetase
A3L08_08860	ENOG4105DP9	ABC transporter
A3L08_08880	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
A3L08_08890	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
A3L08_08920	ENOG4105VKD	bioY protein
A3L08_08925	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
A3L08_08930	ENOG4108JJB	ABC transporter
A3L08_08935	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
A3L08_08980	ENOG4107QVT	Binding-protein-dependent transport systems, inner membrane component
A3L08_08985	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
A3L08_09010	ENOG4105BZA	Phosphoglycerate kinase
A3L08_09030	ENOG4107SSZ	Phosphatase
A3L08_09035	ENOG4105D5P	Methylmalonyl-coA mutase
A3L08_09055	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
A3L08_09070	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
A3L08_09090	ENOG4105ECY	inositol monophosphatase
A3L08_09100	ENOG4107S8T	NAD-dependent 4-hydroxybutyrate dehydrogenase
A3L08_09115	ENOG4105P4J	Allophanate hydrolase, subunit 1
A3L08_09120	ENOG4105E7W	lamb ycsf family protein
A3L08_09165	ENOG4107QX8	SPFH domain, Band 7 family protein
A3L08_09170	ENOG4107QMS	site-determining protein
A3L08_09185	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
A3L08_09200	ENOG4108RCS	geranylgeranylglyceryl phosphate synthase
A3L08_09230	ENOG4105DVT	helicase
A3L08_09245	ENOG4105CN9	Peptidase m42 family protein
A3L08_09250	ENOG4105PW4	Sugar fermentation stimulation protein homolog
A3L08_09260	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
A3L08_09275	ENOG4108TVJ	Nitroreductase
A3L08_09285	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
A3L08_09295	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
A3L08_09300	ENOG4105C6T	cysteine synthase
A3L08_09310	ENOG4105CD5	CoA-binding domain protein
A3L08_09335	ENOG4105CSM	endonuclease III
A3L08_09345	ENOG4108Z03	MAF-like protein
A3L08_09360	ENOG4105CTP	PilT protein domain protein
A3L08_09375	ENOG4105CAQ	asparagine synthetase
A3L08_09390	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
A3L08_09410	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
A3L08_09415	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
A3L08_09425	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
A3L08_09440	ENOG4105CD5	CoA-binding domain protein
A3L08_09535	ENOG4107Y70	Heat shock protein
A3L08_09585	ENOG4107SA6	carbon-phosphorus lyase complex accessory protein
A3L08_09595	ENOG4108TVJ	Nitroreductase
A3L08_09605	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
A3L08_09615	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
A3L08_09645	ENOG4105BZ1	(ABC) transporter
A3L08_09650	ENOG4105BZ1	(ABC) transporter
A3L08_09740	ENOG4105EAC	phosphoserine phosphatase
A3L08_09745	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
A3L08_09765	ENOG4106IPI	cyclase, family
A3L08_09770	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
A3L08_09775	ENOG4108R96	Methyltransferase, YaeB family
A3L08_09785	ENOG4108I5D	sulfate abc transporter
A3L08_09790	ENOG4105MRR	Transcriptional regulator (By similarity)
A3L08_09800	ENOG41066FR	extracellular solute-binding protein
A3L08_09815	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
A3L08_09820	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme