A3L08_04830 82a294e63e6b79242b1dff3e01b7316d 106 Hamap MF_01478 50S ribosomal protein L12 [rpl12]. 1 103 14.757 T 23-10-2018 IPR027534 Ribosomal protein L12 family GO:0003735|GO:0005622|GO:0005840|GO:0006414 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_04830 82a294e63e6b79242b1dff3e01b7316d 106 Pfam PF00428 60s Acidic ribosomal protein 16 105 1.1E-19 T 23-10-2018 A3L08_04830 82a294e63e6b79242b1dff3e01b7316d 106 TIGRFAM TIGR03685 ribo_P1_arch: 50S ribosomal protein P1 1 106 1.1E-40 T 23-10-2018 IPR022295 Ribosomal protein L12, archaea GO:0003735|GO:0005840|GO:0006414 A3L08_04830 82a294e63e6b79242b1dff3e01b7316d 106 Gene3D G3DSA:1.10.10.1410 1 58 1.5E-30 T 23-10-2018 IPR038716 Ribosomal protein P1/P2, N-terminal domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_00730 44c2eb56fcc46d918dae90ea752bc3b1 178 Gene3D G3DSA:3.30.300.130 74 178 1.6E-35 T 23-10-2018 IPR034904 Fe-S cluster assembly domain superfamily A3L08_00730 44c2eb56fcc46d918dae90ea752bc3b1 178 SUPERFAMILY SSF117916 79 176 4.9E-32 T 23-10-2018 IPR034904 Fe-S cluster assembly domain superfamily A3L08_00730 44c2eb56fcc46d918dae90ea752bc3b1 178 Pfam PF01883 Iron-sulfur cluster assembly protein 83 155 4.2E-21 T 23-10-2018 IPR002744 MIP18 family-like A3L08_06790 35840157a25ba72faabb89bfff592038 324 SMART SM00729 17 247 2.3E-26 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A3L08_06790 35840157a25ba72faabb89bfff592038 324 PIRSF PIRSF004954 1 319 1.3E-99 T 23-10-2018 IPR005909 Conserved hypothetical protein CHP01210 A3L08_06790 35840157a25ba72faabb89bfff592038 324 Pfam PF04055 Radical SAM superfamily 35 180 5.3E-8 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L08_06790 35840157a25ba72faabb89bfff592038 324 SUPERFAMILY SSF102114 16 255 1.57E-15 T 23-10-2018 A3L08_06790 35840157a25ba72faabb89bfff592038 324 TIGRFAM TIGR01210 TIGR01210: radical SAM enzyme, TIGR01210 family 3 321 4.9E-123 T 23-10-2018 IPR005909 Conserved hypothetical protein CHP01210 A3L08_08065 077b78e4402e0426edfeaeb64f9b5a0a 82 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 39 76 3.6E-5 T 23-10-2018 A3L08_08065 077b78e4402e0426edfeaeb64f9b5a0a 82 SUPERFAMILY SSF53335 5 78 7.66E-12 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L08_08065 077b78e4402e0426edfeaeb64f9b5a0a 82 Gene3D G3DSA:3.40.50.150 12 80 2.4E-9 T 23-10-2018 A3L08_05705 31d5457401d8a2a1a1ca52461a7d12c7 439 TIGRFAM TIGR02153 gatD_arch: glutamyl-tRNA(Gln) amidotransferase, subunit D 32 433 5.8E-192 T 23-10-2018 IPR011878 Glutamyl-tRNA(Gln) amidotransferase subunit D GO:0006450 A3L08_05705 31d5457401d8a2a1a1ca52461a7d12c7 439 SUPERFAMILY SSF53774 89 436 3.27E-116 T 23-10-2018 IPR036152 Asparaginase/glutaminase-like superfamily Reactome: R-HSA-70614 A3L08_05705 31d5457401d8a2a1a1ca52461a7d12c7 439 Pfam PF00710 Asparaginase, N-terminal 95 288 3.8E-60 T 23-10-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 A3L08_05705 31d5457401d8a2a1a1ca52461a7d12c7 439 Gene3D G3DSA:3.40.50.1170 80 301 9.1E-83 T 23-10-2018 IPR037152 L-asparaginase, N-terminal domain superfamily Reactome: R-HSA-70614 A3L08_05705 31d5457401d8a2a1a1ca52461a7d12c7 439 ProSitePatterns PS00144 Asparaginase / glutaminase active site signature 1. 97 105 - T 23-10-2018 IPR020827 Asparaginase/glutaminase, active site 1 GO:0006520 A3L08_05705 31d5457401d8a2a1a1ca52461a7d12c7 439 PRINTS PR00139 Asparaginase/glutaminase family signature 95 106 2.3E-18 T 23-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 A3L08_05705 31d5457401d8a2a1a1ca52461a7d12c7 439 PRINTS PR00139 Asparaginase/glutaminase family signature 354 372 2.3E-18 T 23-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 A3L08_05705 31d5457401d8a2a1a1ca52461a7d12c7 439 PRINTS PR00139 Asparaginase/glutaminase family signature 171 189 2.3E-18 T 23-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 A3L08_05705 31d5457401d8a2a1a1ca52461a7d12c7 439 TIGRFAM TIGR00519 asnASE_I: L-asparaginase, type I 93 429 5.4E-143 T 23-10-2018 IPR006033 L-asparaginase, type I GO:0004067|GO:0006520 Reactome: R-HSA-70614 A3L08_05705 31d5457401d8a2a1a1ca52461a7d12c7 439 Gene3D G3DSA:2.30.30.520 2 78 5.8E-20 T 23-10-2018 IPR037222 GatD, N-terminal A3L08_05705 31d5457401d8a2a1a1ca52461a7d12c7 439 Hamap MF_00586 Glutamyl-tRNA(Gln) amidotransferase subunit D [gatD]. 19 433 48.556 T 23-10-2018 IPR011878 Glutamyl-tRNA(Gln) amidotransferase subunit D GO:0006450 A3L08_05705 31d5457401d8a2a1a1ca52461a7d12c7 439 PIRSF PIRSF500175 13 437 6.5E-185 T 23-10-2018 IPR011878 Glutamyl-tRNA(Gln) amidotransferase subunit D GO:0006450 A3L08_05705 31d5457401d8a2a1a1ca52461a7d12c7 439 PIRSF PIRSF001220 89 428 4.0E-109 T 23-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 A3L08_05705 31d5457401d8a2a1a1ca52461a7d12c7 439 Gene3D G3DSA:3.40.50.40 302 439 2.3E-57 T 23-10-2018 IPR027473 L-asparaginase, C-terminal Reactome: R-HSA-70614 A3L08_05705 31d5457401d8a2a1a1ca52461a7d12c7 439 ProSitePatterns PS00917 Asparaginase / glutaminase active site signature 2. 172 182 - T 23-10-2018 IPR027475 Asparaginase/glutaminase, active site 2 Reactome: R-HSA-70614 A3L08_05705 31d5457401d8a2a1a1ca52461a7d12c7 439 SUPERFAMILY SSF141300 4 76 1.29E-18 T 23-10-2018 IPR037222 GatD, N-terminal A3L08_05705 31d5457401d8a2a1a1ca52461a7d12c7 439 SMART SM00870 94 417 1.3E-150 T 23-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 A3L08_05430 be42e432fde9485ce66ad8a591f9b233 222 Gene3D G3DSA:3.40.50.2020 1 218 6.6E-60 T 23-10-2018 A3L08_05430 be42e432fde9485ce66ad8a591f9b233 222 SUPERFAMILY SSF53271 13 217 1.41E-57 T 23-10-2018 IPR029057 Phosphoribosyltransferase-like A3L08_05430 be42e432fde9485ce66ad8a591f9b233 222 Hamap MF_01218_A Uracil phosphoribosyltransferase [upp]. 9 217 40.524 T 23-10-2018 IPR034331 Uracil phosphoribosyltransferase, archaea GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 A3L08_05430 be42e432fde9485ce66ad8a591f9b233 222 Pfam PF14681 Uracil phosphoribosyltransferase 15 218 6.5E-51 T 23-10-2018 A3L08_05430 be42e432fde9485ce66ad8a591f9b233 222 TIGRFAM TIGR01091 upp: uracil phosphoribosyltransferase 15 218 6.1E-77 T 23-10-2018 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 A3L08_00285 e68cd72b9c3b1198c973635ebbd8a526 326 SMART SM00382 34 247 1.4E-12 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L08_00285 e68cd72b9c3b1198c973635ebbd8a526 326 SUPERFAMILY SSF52540 34 323 2.39E-68 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_00285 e68cd72b9c3b1198c973635ebbd8a526 326 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 239 325 9.0E-31 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A3L08_00285 e68cd72b9c3b1198c973635ebbd8a526 326 Gene3D G3DSA:3.40.50.300 3 326 9.6E-99 T 23-10-2018 A3L08_00285 e68cd72b9c3b1198c973635ebbd8a526 326 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 241 305 8.9E-21 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A3L08_00285 e68cd72b9c3b1198c973635ebbd8a526 326 ProSitePatterns PS00211 ABC transporters family signature. 162 176 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L08_00285 e68cd72b9c3b1198c973635ebbd8a526 326 Pfam PF00005 ABC transporter 26 189 3.1E-25 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L08_01525 b5f75d6740934dff7d4bb3f58e8da35d 195 SUPERFAMILY SSF52141 8 191 1.14E-60 T 23-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A3L08_01525 b5f75d6740934dff7d4bb3f58e8da35d 195 Pfam PF03167 Uracil DNA glycosylase superfamily 31 182 2.5E-45 T 23-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A3L08_01525 b5f75d6740934dff7d4bb3f58e8da35d 195 SMART SM00987 31 185 1.5E-36 T 23-10-2018 A3L08_01525 b5f75d6740934dff7d4bb3f58e8da35d 195 SMART SM00986 31 185 1.5E-36 T 23-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A3L08_01525 b5f75d6740934dff7d4bb3f58e8da35d 195 TIGRFAM TIGR00758 UDG_fam4: uracil-DNA glycosylase, family 4 17 191 3.9E-77 T 23-10-2018 IPR005273 Uracil-DNA glycosylase family 4 A3L08_01525 b5f75d6740934dff7d4bb3f58e8da35d 195 Gene3D G3DSA:3.40.470.10 5 193 6.0E-70 T 23-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A3L08_02550 6f3b6b0cdcf7f7ad4b6efe1632390fda 139 TIGRFAM TIGR03330 SAM_DCase_Bsu: S-adenosylmethionine decarboxylase proenzyme 3 113 5.7E-45 T 23-10-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 A3L08_02550 6f3b6b0cdcf7f7ad4b6efe1632390fda 139 SUPERFAMILY SSF56276 3 117 7.26E-42 T 23-10-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 A3L08_02550 6f3b6b0cdcf7f7ad4b6efe1632390fda 139 Pfam PF02675 S-adenosylmethionine decarboxylase 7 113 2.1E-39 T 23-10-2018 IPR003826 S-adenosylmethionine decarboxylase family, prokaryotic GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 A3L08_02550 6f3b6b0cdcf7f7ad4b6efe1632390fda 139 Gene3D G3DSA:3.30.160.750 63 127 6.8E-25 T 23-10-2018 A3L08_02550 6f3b6b0cdcf7f7ad4b6efe1632390fda 139 Hamap MF_00464 S-adenosylmethionine decarboxylase proenzyme [speH]. 1 117 31.587 T 23-10-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 A3L08_02550 6f3b6b0cdcf7f7ad4b6efe1632390fda 139 Gene3D G3DSA:3.30.360.110 1 62 1.9E-20 T 23-10-2018 A3L08_06740 fa0320be3f56b67a3e8bb1b2daa81682 744 Gene3D G3DSA:1.10.730.10 398 548 1.8E-104 T 23-10-2018 A3L08_06740 fa0320be3f56b67a3e8bb1b2daa81682 744 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 5 549 2.1E-176 T 23-10-2018 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A3L08_06740 fa0320be3f56b67a3e8bb1b2daa81682 744 Pfam PF09334 tRNA synthetases class I (M) 4 409 1.9E-158 T 23-10-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L08_06740 fa0320be3f56b67a3e8bb1b2daa81682 744 Pfam PF01588 Putative tRNA binding domain 650 741 1.6E-32 T 23-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 A3L08_06740 fa0320be3f56b67a3e8bb1b2daa81682 744 Pfam PF08264 Anticodon-binding domain of tRNA 430 525 1.0E-13 T 23-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 A3L08_06740 fa0320be3f56b67a3e8bb1b2daa81682 744 Gene3D G3DSA:2.170.220.10 98 252 1.2E-142 T 23-10-2018 A3L08_06740 fa0320be3f56b67a3e8bb1b2daa81682 744 SUPERFAMILY SSF47323 398 589 4.67E-48 T 23-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L08_06740 fa0320be3f56b67a3e8bb1b2daa81682 744 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 11 22 - T 23-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L08_06740 fa0320be3f56b67a3e8bb1b2daa81682 744 SUPERFAMILY SSF57770 139 173 1.02E-10 T 23-10-2018 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A3L08_06740 fa0320be3f56b67a3e8bb1b2daa81682 744 Hamap MF_00098 Methionine--tRNA ligase [metG]. 2 560 42.835 T 23-10-2018 IPR023458 Methionine-tRNA ligase, type 1 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A3L08_06740 fa0320be3f56b67a3e8bb1b2daa81682 744 PRINTS PR01041 Methionyl-tRNA synthetase signature 6 19 1.1E-32 T 23-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A3L08_06740 fa0320be3f56b67a3e8bb1b2daa81682 744 PRINTS PR01041 Methionyl-tRNA synthetase signature 39 53 1.1E-32 T 23-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A3L08_06740 fa0320be3f56b67a3e8bb1b2daa81682 744 PRINTS PR01041 Methionyl-tRNA synthetase signature 396 407 1.1E-32 T 23-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A3L08_06740 fa0320be3f56b67a3e8bb1b2daa81682 744 PRINTS PR01041 Methionyl-tRNA synthetase signature 252 263 1.1E-32 T 23-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A3L08_06740 fa0320be3f56b67a3e8bb1b2daa81682 744 PRINTS PR01041 Methionyl-tRNA synthetase signature 294 309 1.1E-32 T 23-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A3L08_06740 fa0320be3f56b67a3e8bb1b2daa81682 744 PRINTS PR01041 Methionyl-tRNA synthetase signature 87 98 1.1E-32 T 23-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A3L08_06740 fa0320be3f56b67a3e8bb1b2daa81682 744 SUPERFAMILY SSF50249 643 743 4.9E-38 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L08_06740 fa0320be3f56b67a3e8bb1b2daa81682 744 Gene3D G3DSA:2.40.50.140 638 744 1.1E-44 T 23-10-2018 A3L08_06740 fa0320be3f56b67a3e8bb1b2daa81682 744 Gene3D G3DSA:1.10.730.10 341 581 1.8E-104 T 23-10-2018 A3L08_06740 fa0320be3f56b67a3e8bb1b2daa81682 744 SUPERFAMILY SSF52374 3 395 1.9E-105 T 23-10-2018 A3L08_06740 fa0320be3f56b67a3e8bb1b2daa81682 744 Gene3D G3DSA:3.40.50.620 5 316 1.2E-142 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L08_06740 fa0320be3f56b67a3e8bb1b2daa81682 744 TIGRFAM TIGR00399 metG_C_term: methionine--tRNA ligase, beta subunit 618 744 6.7E-41 T 23-10-2018 IPR004495 Methionyl-tRNA synthetase, beta subunit, C-terminal GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A3L08_05270 31198a5cbb1cd26ed5c704d902b127be 96 Pfam PF01458 Uncharacterized protein family (UPF0051) 20 70 7.9E-15 T 23-10-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 A3L08_05270 31198a5cbb1cd26ed5c704d902b127be 96 SUPERFAMILY SSF101960 21 84 5.62E-16 T 23-10-2018 IPR037284 SUF system FeS cluster assembly, SufBD superfamily A3L08_06525 2da0069db3ffebe158a2445ffe8474af 544 SUPERFAMILY SSF143243 4 179 1.7E-37 T 23-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L08_06525 2da0069db3ffebe158a2445ffe8474af 544 Gene3D G3DSA:3.30.460.80 1 125 1.0E-13 T 23-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L08_06525 2da0069db3ffebe158a2445ffe8474af 544 Gene3D G3DSA:1.10.645.20 166 522 5.0E-130 T 23-10-2018 IPR038290 NADH-quinone oxidoreductase, subunit D superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L08_06525 2da0069db3ffebe158a2445ffe8474af 544 Pfam PF00374 Nickel-dependent hydrogenase 203 273 9.3E-15 T 23-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 A3L08_06525 2da0069db3ffebe158a2445ffe8474af 544 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 79 132 2.0E-11 T 23-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L08_06525 2da0069db3ffebe158a2445ffe8474af 544 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 450 522 3.7E-15 T 23-10-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L08_06525 2da0069db3ffebe158a2445ffe8474af 544 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 280 445 2.4E-48 T 23-10-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L08_06525 2da0069db3ffebe158a2445ffe8474af 544 SUPERFAMILY SSF56762 177 522 3.27E-116 T 23-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L08_06525 2da0069db3ffebe158a2445ffe8474af 544 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 28 147 1.7E-24 T 23-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L08_00845 569e644a134bf2dc3dd8df34427a98e2 312 Pfam PF09202 Rio2, N-terminal 13 93 1.8E-22 T 23-10-2018 IPR015285 RIO2 kinase winged helix domain, N-terminal GO:0004674|GO:0005524|GO:0006468 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6791226 A3L08_00845 569e644a134bf2dc3dd8df34427a98e2 312 Pfam PF01163 RIO1 family 111 287 5.8E-46 T 23-10-2018 A3L08_00845 569e644a134bf2dc3dd8df34427a98e2 312 Gene3D G3DSA:3.30.200.20 98 196 6.0E-23 T 23-10-2018 A3L08_00845 569e644a134bf2dc3dd8df34427a98e2 312 Gene3D G3DSA:1.10.510.10 203 297 4.7E-16 T 23-10-2018 A3L08_00845 569e644a134bf2dc3dd8df34427a98e2 312 SUPERFAMILY SSF46785 9 94 1.41E-22 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L08_00845 569e644a134bf2dc3dd8df34427a98e2 312 SMART SM00090 68 299 7.7E-79 T 23-10-2018 IPR000687 RIO kinase GO:0004674|GO:0005524 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6791226 A3L08_00845 569e644a134bf2dc3dd8df34427a98e2 312 SUPERFAMILY SSF56112 102 273 4.45E-25 T 23-10-2018 IPR011009 Protein kinase-like domain superfamily A3L08_00845 569e644a134bf2dc3dd8df34427a98e2 312 Gene3D G3DSA:1.10.10.10 5 94 2.2E-15 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L08_03180 5d621409892340302cfbd4407a3a6bda 660 Pfam PF13086 AAA domain 175 424 4.9E-56 T 23-10-2018 A3L08_03180 5d621409892340302cfbd4407a3a6bda 660 Gene3D G3DSA:3.40.50.300 452 658 1.9E-61 T 23-10-2018 A3L08_03180 5d621409892340302cfbd4407a3a6bda 660 Gene3D G3DSA:2.40.30.270 33 127 4.6E-94 T 23-10-2018 A3L08_03180 5d621409892340302cfbd4407a3a6bda 660 TIGRFAM TIGR00376 TIGR00376: putative DNA helicase 19 652 7.4E-247 T 23-10-2018 IPR004483 Helicase SMUBP-2/Hcs1-like GO:0003677|GO:0005524 A3L08_03180 5d621409892340302cfbd4407a3a6bda 660 Gene3D G3DSA:3.40.50.300 14 435 4.6E-94 T 23-10-2018 A3L08_03180 5d621409892340302cfbd4407a3a6bda 660 Pfam PF13087 AAA domain 429 630 3.7E-57 T 23-10-2018 A3L08_03180 5d621409892340302cfbd4407a3a6bda 660 SUPERFAMILY SSF52540 169 639 1.46E-64 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_01560 d671779834c7d9249481390375cee83c 146 TIGRFAM TIGR00721 tfx: DNA-binding protein, Tfx family 3 136 3.0E-58 T 23-10-2018 IPR004645 DNA-binding protein Tfx, archaea GO:0003677 A3L08_01560 d671779834c7d9249481390375cee83c 146 Pfam PF04545 Sigma-70, region 4 6 48 2.0E-7 T 23-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 A3L08_01560 d671779834c7d9249481390375cee83c 146 Pfam PF14601 DNA_binding protein, TFX, C-term 51 131 7.2E-23 T 23-10-2018 IPR029291 DNA binding protein Tfx, C-terminal A3L08_01560 d671779834c7d9249481390375cee83c 146 SMART SM00421 3 60 0.009 T 23-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A3L08_01560 d671779834c7d9249481390375cee83c 146 Gene3D G3DSA:3.30.1190.10 16 134 1.6E-36 T 23-10-2018 IPR036657 DNA-binding protein Tfx superfamily, archaea GO:0003677 A3L08_01560 d671779834c7d9249481390375cee83c 146 PIRSF PIRSF004932 2 146 8.8E-66 T 23-10-2018 IPR018384 DNA-binding protein Tfx, euryarchaeota GO:0003677 A3L08_01560 d671779834c7d9249481390375cee83c 146 SUPERFAMILY SSF89915 16 111 3.53E-23 T 23-10-2018 IPR036657 DNA-binding protein Tfx superfamily, archaea GO:0003677 A3L08_04825 a63f95ac44d9c90132f55de852bf713f 340 SUPERFAMILY SSF160369 5 141 1.2E-25 T 23-10-2018 A3L08_04825 a63f95ac44d9c90132f55de852bf713f 340 Gene3D G3DSA:3.90.105.20 107 186 3.6E-74 T 23-10-2018 A3L08_04825 a63f95ac44d9c90132f55de852bf713f 340 Gene3D G3DSA:3.30.70.1730 15 210 3.6E-74 T 23-10-2018 A3L08_04825 a63f95ac44d9c90132f55de852bf713f 340 Pfam PF00466 Ribosomal protein L10 5 105 1.1E-21 T 23-10-2018 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 A3L08_04825 a63f95ac44d9c90132f55de852bf713f 340 Pfam PF00428 60s Acidic ribosomal protein 232 339 5.8E-7 T 23-10-2018 A3L08_04825 a63f95ac44d9c90132f55de852bf713f 340 Hamap MF_00280 50S ribosomal protein L10 [rpl10]. 1 283 35.843 T 23-10-2018 IPR022909 50S ribosomal protein L10, archaea A3L08_04870 4f09f0d1d54f9696f5d38feb26c5d18f 572 Gene3D G3DSA:2.40.240.10 418 516 1.4E-43 T 23-10-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, N-terminal Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A3L08_04870 4f09f0d1d54f9696f5d38feb26c5d18f 572 Gene3D G3DSA:2.40.240.100 409 571 1.4E-43 T 23-10-2018 A3L08_04870 4f09f0d1d54f9696f5d38feb26c5d18f 572 Hamap MF_02076 Glutamate--tRNA ligase [gltX]. 7 570 39.938 T 23-10-2018 IPR004526 Glutamyl-tRNA synthetase, archaeal/eukaryotic cytosolic GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 A3L08_04870 4f09f0d1d54f9696f5d38feb26c5d18f 572 PRINTS PR00987 Glutamyl-tRNA synthetase signature 103 115 3.7E-21 T 23-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 A3L08_04870 4f09f0d1d54f9696f5d38feb26c5d18f 572 PRINTS PR00987 Glutamyl-tRNA synthetase signature 117 128 3.7E-21 T 23-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 A3L08_04870 4f09f0d1d54f9696f5d38feb26c5d18f 572 PRINTS PR00987 Glutamyl-tRNA synthetase signature 132 145 3.7E-21 T 23-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 A3L08_04870 4f09f0d1d54f9696f5d38feb26c5d18f 572 PRINTS PR00987 Glutamyl-tRNA synthetase signature 296 304 3.7E-21 T 23-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 A3L08_04870 4f09f0d1d54f9696f5d38feb26c5d18f 572 PRINTS PR00987 Glutamyl-tRNA synthetase signature 280 290 3.7E-21 T 23-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 A3L08_04870 4f09f0d1d54f9696f5d38feb26c5d18f 572 SUPERFAMILY SSF52374 99 415 1.98E-90 T 23-10-2018 A3L08_04870 4f09f0d1d54f9696f5d38feb26c5d18f 572 SUPERFAMILY SSF50715 409 569 3.66E-29 T 23-10-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A3L08_04870 4f09f0d1d54f9696f5d38feb26c5d18f 572 Gene3D G3DSA:3.40.50.620 93 408 2.0E-119 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L08_04870 4f09f0d1d54f9696f5d38feb26c5d18f 572 TIGRFAM TIGR00463 gltX_arch: glutamate--tRNA ligase 3 572 5.3E-213 T 23-10-2018 IPR004526 Glutamyl-tRNA synthetase, archaeal/eukaryotic cytosolic GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 A3L08_04870 4f09f0d1d54f9696f5d38feb26c5d18f 572 Pfam PF03950 tRNA synthetases class I (E and Q), anti-codon binding domain 409 558 5.0E-28 T 23-10-2018 IPR020059 Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A3L08_04870 4f09f0d1d54f9696f5d38feb26c5d18f 572 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 99 403 4.4E-84 T 23-10-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0004812|GO:0005524|GO:0043039 A3L08_04225 81000a9d0bebd20986c4443368e06178 140 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 12 137 23.642 T 23-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 A3L08_04225 81000a9d0bebd20986c4443368e06178 140 Pfam PF00411 Ribosomal protein S11 18 136 2.1E-47 T 23-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 A3L08_04225 81000a9d0bebd20986c4443368e06178 140 PIRSF PIRSF002131 1 139 7.0E-36 T 23-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 A3L08_04225 81000a9d0bebd20986c4443368e06178 140 TIGRFAM TIGR03628 arch_S11P: ribosomal protein uS11 16 132 7.2E-67 T 23-10-2018 IPR019961 Ribosomal protein S11, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L08_04225 81000a9d0bebd20986c4443368e06178 140 Gene3D G3DSA:3.30.420.80 4 140 4.1E-65 T 23-10-2018 IPR036967 Ribosomal protein S11 superfamily GO:0003735|GO:0005840|GO:0006412 A3L08_04225 81000a9d0bebd20986c4443368e06178 140 SUPERFAMILY SSF53137 12 138 3.53E-39 T 23-10-2018 A3L08_04225 81000a9d0bebd20986c4443368e06178 140 ProSitePatterns PS00054 Ribosomal protein S11 signature. 105 127 - T 23-10-2018 IPR018102 Ribosomal S11, conserved site A3L08_09730 9848813fd8fa398009fdafd184c1bee0 111 Pfam PF04266 ASCH domain 7 108 1.1E-14 T 23-10-2018 IPR007374 ASCH domain A3L08_09730 9848813fd8fa398009fdafd184c1bee0 111 PIRSF PIRSF016134 2 111 1.2E-43 T 23-10-2018 IPR016645 Uncharacterised conserved protein UCP016134 A3L08_09730 9848813fd8fa398009fdafd184c1bee0 111 Gene3D G3DSA:2.30.130.30 1 111 1.6E-39 T 23-10-2018 A3L08_09730 9848813fd8fa398009fdafd184c1bee0 111 SUPERFAMILY SSF88697 1 108 4.1E-31 T 23-10-2018 IPR015947 PUA-like superfamily A3L08_09730 9848813fd8fa398009fdafd184c1bee0 111 SMART SM01022 6 109 3.2E-11 T 23-10-2018 IPR007374 ASCH domain A3L08_00610 84fdf32b89f1298c0b543c257c1bf612 150 SUPERFAMILY SSF54909 65 150 1.01E-20 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel A3L08_00610 84fdf32b89f1298c0b543c257c1bf612 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 5 21 5.0E-17 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L08_00610 84fdf32b89f1298c0b543c257c1bf612 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 32 51 5.0E-17 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L08_00610 84fdf32b89f1298c0b543c257c1bf612 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 21 32 5.0E-17 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L08_00610 84fdf32b89f1298c0b543c257c1bf612 150 Pfam PF13404 AsnC-type helix-turn-helix domain 5 46 5.2E-17 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L08_00610 84fdf32b89f1298c0b543c257c1bf612 150 Pfam PF01037 Lrp/AsnC ligand binding domain 71 140 3.3E-18 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A3L08_00610 84fdf32b89f1298c0b543c257c1bf612 150 Gene3D G3DSA:1.10.10.10 2 55 3.7E-23 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L08_00610 84fdf32b89f1298c0b543c257c1bf612 150 SMART SM00344 5 111 5.3E-49 T 23-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A3L08_00610 84fdf32b89f1298c0b543c257c1bf612 150 Gene3D G3DSA:3.30.70.920 57 150 2.8E-26 T 23-10-2018 A3L08_00610 84fdf32b89f1298c0b543c257c1bf612 150 SUPERFAMILY SSF46785 5 65 9.69E-18 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L08_05690 e7fc2ae0908b9096657a474185c54d98 408 ProSitePatterns PS00318 Hydroxymethylglutaryl-coenzyme A reductases signature 2. 340 347 - T 23-10-2018 IPR023076 Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A3L08_05690 e7fc2ae0908b9096657a474185c54d98 408 Gene3D G3DSA:3.90.770.10 75 395 6.1E-134 T 23-10-2018 IPR023074 Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic domain superfamily GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A3L08_05690 e7fc2ae0908b9096657a474185c54d98 408 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 328 349 1.4E-59 T 23-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A3L08_05690 e7fc2ae0908b9096657a474185c54d98 408 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 276 302 1.4E-59 T 23-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A3L08_05690 e7fc2ae0908b9096657a474185c54d98 408 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 64 85 1.4E-59 T 23-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A3L08_05690 e7fc2ae0908b9096657a474185c54d98 408 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 95 115 1.4E-59 T 23-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A3L08_05690 e7fc2ae0908b9096657a474185c54d98 408 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 185 203 1.4E-59 T 23-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A3L08_05690 e7fc2ae0908b9096657a474185c54d98 408 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 225 250 1.4E-59 T 23-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A3L08_05690 e7fc2ae0908b9096657a474185c54d98 408 TIGRFAM TIGR00533 HMG_CoA_R_NADP: hydroxymethylglutaryl-CoA reductase (NADPH) 4 408 4.3E-169 T 23-10-2018 IPR004554 Hydroxymethylglutaryl-CoA reductase, eukaryotic/archaeal type GO:0004420|GO:0008299|GO:0016021|GO:0050661|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A3L08_05690 e7fc2ae0908b9096657a474185c54d98 408 ProSitePatterns PS00066 Hydroxymethylglutaryl-coenzyme A reductases signature 1. 187 201 - T 23-10-2018 IPR023076 Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A3L08_05690 e7fc2ae0908b9096657a474185c54d98 408 SUPERFAMILY SSF55035 129 244 4.19E-40 T 23-10-2018 IPR009023 Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain superfamily GO:0050662 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A3L08_05690 e7fc2ae0908b9096657a474185c54d98 408 SUPERFAMILY SSF56542 4 398 5.36E-94 T 23-10-2018 IPR009029 Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding domain superfamily GO:0015936|GO:0016616|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A3L08_05690 e7fc2ae0908b9096657a474185c54d98 408 Gene3D G3DSA:3.30.70.420 129 244 6.1E-134 T 23-10-2018 IPR009023 Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain superfamily GO:0050662 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A3L08_05690 e7fc2ae0908b9096657a474185c54d98 408 Gene3D G3DSA:1.10.3270.10 1 74 8.2E-8 T 23-10-2018 IPR023282 Hydroxymethylglutaryl-CoA reductase, N-terminal GO:0004420 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A3L08_05690 e7fc2ae0908b9096657a474185c54d98 408 Pfam PF00368 Hydroxymethylglutaryl-coenzyme A reductase 32 408 2.1E-141 T 23-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A3L08_04595 37f340f1040f0e94f7e3fd296fe4c887 438 PRINTS PR01042 Aspartyl-tRNA synthetase signature 204 217 1.3E-22 T 23-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L08_04595 37f340f1040f0e94f7e3fd296fe4c887 438 PRINTS PR01042 Aspartyl-tRNA synthetase signature 393 407 1.3E-22 T 23-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L08_04595 37f340f1040f0e94f7e3fd296fe4c887 438 PRINTS PR01042 Aspartyl-tRNA synthetase signature 353 369 1.3E-22 T 23-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L08_04595 37f340f1040f0e94f7e3fd296fe4c887 438 PRINTS PR01042 Aspartyl-tRNA synthetase signature 187 199 1.3E-22 T 23-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L08_04595 37f340f1040f0e94f7e3fd296fe4c887 438 SUPERFAMILY SSF55681 96 437 1.99E-99 T 23-10-2018 A3L08_04595 37f340f1040f0e94f7e3fd296fe4c887 438 TIGRFAM TIGR00458 aspS_nondisc: aspartate--tRNA(Asn) ligase 5 438 1.9E-184 T 23-10-2018 IPR004523 Aspartate-tRNA synthetase, type 2 GO:0000166|GO:0004815|GO:0005524|GO:0005737|GO:0006422 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A3L08_04595 37f340f1040f0e94f7e3fd296fe4c887 438 Hamap MF_02075 Aspartate--tRNA(Asp) ligase [aspS]. 2 438 43.513 T 23-10-2018 IPR004523 Aspartate-tRNA synthetase, type 2 GO:0000166|GO:0004815|GO:0005524|GO:0005737|GO:0006422 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A3L08_04595 37f340f1040f0e94f7e3fd296fe4c887 438 Gene3D G3DSA:2.40.50.140 1 105 1.6E-28 T 23-10-2018 A3L08_04595 37f340f1040f0e94f7e3fd296fe4c887 438 SUPERFAMILY SSF50249 1 102 1.68E-27 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L08_04595 37f340f1040f0e94f7e3fd296fe4c887 438 Gene3D G3DSA:3.30.930.10 107 438 3.2E-122 T 23-10-2018 A3L08_04595 37f340f1040f0e94f7e3fd296fe4c887 438 Pfam PF01336 OB-fold nucleic acid binding domain 19 98 4.7E-12 T 23-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 A3L08_04595 37f340f1040f0e94f7e3fd296fe4c887 438 Pfam PF00152 tRNA synthetases class II (D, K and N) 118 432 4.8E-96 T 23-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L08_01425 8873a4d022db5fe8e6adcbb6cc0e2248 202 Gene3D G3DSA:3.40.50.150 19 194 8.0E-38 T 23-10-2018 A3L08_01425 8873a4d022db5fe8e6adcbb6cc0e2248 202 SUPERFAMILY SSF53335 10 199 4.71E-40 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L08_01425 8873a4d022db5fe8e6adcbb6cc0e2248 202 Pfam PF08241 Methyltransferase domain 41 135 6.8E-26 T 23-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 A3L08_01425 8873a4d022db5fe8e6adcbb6cc0e2248 202 ProSitePatterns PS01184 ubiE/COQ5 methyltransferase family signature 2. 125 139 - T 23-10-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 A3L08_09055 9c9939f07c1a62c9e5c8b9a2831152d3 1188 PIRSF PIRSF005719 1 1168 5.7E-281 T 23-10-2018 IPR024704 Structural maintenance of chromosomes protein A3L08_09055 9c9939f07c1a62c9e5c8b9a2831152d3 1188 SUPERFAMILY SSF75553 482 677 6.54E-51 T 23-10-2018 IPR036277 SMCs flexible hinge superfamily GO:0005515|GO:0005524|GO:0005694|GO:0051276 A3L08_09055 9c9939f07c1a62c9e5c8b9a2831152d3 1188 TIGRFAM TIGR02168 SMC_prok_B: chromosome segregation protein SMC 3 1161 2.3E-235 T 23-10-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 A3L08_09055 9c9939f07c1a62c9e5c8b9a2831152d3 1188 SUPERFAMILY SSF52540 1 1168 1.84E-56 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_09055 9c9939f07c1a62c9e5c8b9a2831152d3 1188 TIGRFAM TIGR02169 SMC_prok_A: chromosome segregation protein SMC 3 1161 0.0 T 23-10-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 A3L08_09055 9c9939f07c1a62c9e5c8b9a2831152d3 1188 Gene3D G3DSA:3.40.50.300 1010 1181 7.0E-60 T 23-10-2018 A3L08_09055 9c9939f07c1a62c9e5c8b9a2831152d3 1188 SUPERFAMILY SSF57997 730 964 7.19E-5 T 23-10-2018 A3L08_09055 9c9939f07c1a62c9e5c8b9a2831152d3 1188 Gene3D G3DSA:3.40.50.300 2 233 1.5E-60 T 23-10-2018 A3L08_09055 9c9939f07c1a62c9e5c8b9a2831152d3 1188 Hamap MF_01894 Chromosome partition protein Smc [smc]. 2 1163 21.309 T 23-10-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 A3L08_09055 9c9939f07c1a62c9e5c8b9a2831152d3 1188 Pfam PF02463 RecF/RecN/SMC N terminal domain 3 1153 7.9E-78 T 23-10-2018 IPR003395 RecF/RecN/SMC, N-terminal A3L08_09055 9c9939f07c1a62c9e5c8b9a2831152d3 1188 Gene3D G3DSA:1.20.1060.20 507 661 9.1E-46 T 23-10-2018 A3L08_09055 9c9939f07c1a62c9e5c8b9a2831152d3 1188 Gene3D G3DSA:3.30.70.1620 581 658 9.1E-46 T 23-10-2018 A3L08_09055 9c9939f07c1a62c9e5c8b9a2831152d3 1188 Gene3D G3DSA:1.20.5.340 376 496 5.2E-5 T 23-10-2018 A3L08_09055 9c9939f07c1a62c9e5c8b9a2831152d3 1188 Gene3D G3DSA:1.20.5.340 777 876 1.1E-7 T 23-10-2018 A3L08_09055 9c9939f07c1a62c9e5c8b9a2831152d3 1188 SMART SM00968 520 632 1.1E-42 T 23-10-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 A3L08_09055 9c9939f07c1a62c9e5c8b9a2831152d3 1188 SUPERFAMILY SSF57997 379 511 5.89E-7 T 23-10-2018 A3L08_09055 9c9939f07c1a62c9e5c8b9a2831152d3 1188 Pfam PF06470 SMC proteins Flexible Hinge Domain 520 630 1.3E-33 T 23-10-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 A3L08_04575 fc5a17313077cd9252ed0e4d307ee6cc 243 Gene3D G3DSA:3.90.1070.10 88 155 8.8E-73 T 23-10-2018 A3L08_04575 fc5a17313077cd9252ed0e4d307ee6cc 243 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 7 198 2.5E-15 T 23-10-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 A3L08_04575 fc5a17313077cd9252ed0e4d307ee6cc 243 SUPERFAMILY SSF56784 3 230 1.68E-39 T 23-10-2018 IPR036412 HAD-like superfamily A3L08_04575 fc5a17313077cd9252ed0e4d307ee6cc 243 TIGRFAM TIGR01482 SPP-subfamily: sucrose-phosphate phosphatase subfamily 7 234 6.4E-72 T 23-10-2018 A3L08_04575 fc5a17313077cd9252ed0e4d307ee6cc 243 TIGRFAM TIGR01487 Pglycolate_arch: phosphoglycolate phosphatase, TA0175-type 4 224 7.1E-75 T 23-10-2018 A3L08_04575 fc5a17313077cd9252ed0e4d307ee6cc 243 Hamap MF_01419 Phosphoglycolate phosphatase. 4 231 32.634 T 23-10-2018 IPR006382 Phosphoglycolate phosphatase GO:0000287|GO:0008967|GO:0016311 KEGG: 00630+3.1.3.18|MetaCyc: PWY-181 A3L08_04575 fc5a17313077cd9252ed0e4d307ee6cc 243 Pfam PF08282 haloacid dehalogenase-like hydrolase 141 223 2.1E-18 T 23-10-2018 A3L08_04575 fc5a17313077cd9252ed0e4d307ee6cc 243 Pfam PF08282 haloacid dehalogenase-like hydrolase 7 80 4.1E-6 T 23-10-2018 A3L08_04575 fc5a17313077cd9252ed0e4d307ee6cc 243 Gene3D G3DSA:3.40.50.1000 5 225 8.8E-73 T 23-10-2018 IPR023214 HAD superfamily A3L08_09800 9b93a8250185d1f7c6f51309563692df 335 Gene3D G3DSA:3.40.190.10 113 279 3.1E-134 T 23-10-2018 A3L08_09800 9b93a8250185d1f7c6f51309563692df 335 SUPERFAMILY SSF53850 24 327 7.53E-56 T 23-10-2018 A3L08_09800 9b93a8250185d1f7c6f51309563692df 335 TIGRFAM TIGR03730 tungstate_WtpA: tungstate ABC transporter binding protein WtpA 26 297 1.6E-125 T 23-10-2018 IPR022498 Tungstate ABC transporter, substrate-binding protein WtpA GO:1901359 A3L08_09800 9b93a8250185d1f7c6f51309563692df 335 Pfam PF13531 Bacterial extracellular solute-binding protein 28 309 9.4E-36 T 23-10-2018 A3L08_09800 9b93a8250185d1f7c6f51309563692df 335 Gene3D G3DSA:3.40.190.10 27 328 3.1E-134 T 23-10-2018 A3L08_08500 0026dea0148f0f13583a909e33010692 209 Pfam PF08241 Methyltransferase domain 44 128 2.3E-18 T 23-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 A3L08_08500 0026dea0148f0f13583a909e33010692 209 SUPERFAMILY SSF53335 7 182 8.52E-35 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L08_08500 0026dea0148f0f13583a909e33010692 209 Gene3D G3DSA:3.40.50.150 2 209 9.4E-62 T 23-10-2018 A3L08_06720 b9179a549d897549e783c75e3dd335ad 244 Pfam PF01925 Sulfite exporter TauE/SafE 8 242 4.7E-51 T 23-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 A3L08_04300 6c2a2a478e3f897bb4c00017f9066c7c 253 Gene3D G3DSA:3.60.21.10 1 253 6.7E-49 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like A3L08_04300 6c2a2a478e3f897bb4c00017f9066c7c 253 SUPERFAMILY SSF56300 1 252 1.58E-57 T 23-10-2018 A3L08_07340 1c4688cf5422ee9c2310592a6d469da0 386 Hamap MF_00132 Type 2 DNA topoisomerase 6 subunit A [top6A]. 17 385 40.275 T 23-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 A3L08_07340 1c4688cf5422ee9c2310592a6d469da0 386 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 147 162 5.2E-29 T 23-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 A3L08_07340 1c4688cf5422ee9c2310592a6d469da0 386 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 129 146 5.2E-29 T 23-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 A3L08_07340 1c4688cf5422ee9c2310592a6d469da0 386 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 226 247 5.2E-29 T 23-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 A3L08_07340 1c4688cf5422ee9c2310592a6d469da0 386 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 107 118 5.2E-29 T 23-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 A3L08_07340 1c4688cf5422ee9c2310592a6d469da0 386 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 202 219 5.2E-29 T 23-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 A3L08_07340 1c4688cf5422ee9c2310592a6d469da0 386 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 258 274 5.2E-29 T 23-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 A3L08_07340 1c4688cf5422ee9c2310592a6d469da0 386 SUPERFAMILY SSF56726 81 383 4.71E-79 T 23-10-2018 IPR036078 Spo11/DNA topoisomerase VI subunit A superfamily GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 A3L08_07340 1c4688cf5422ee9c2310592a6d469da0 386 Gene3D G3DSA:3.40.1360.10 156 385 1.6E-64 T 23-10-2018 A3L08_07340 1c4688cf5422ee9c2310592a6d469da0 386 Gene3D G3DSA:1.10.10.10 11 155 1.1E-52 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L08_07340 1c4688cf5422ee9c2310592a6d469da0 386 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 49 69 3.5E-47 T 23-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 A3L08_07340 1c4688cf5422ee9c2310592a6d469da0 386 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 123 140 3.5E-47 T 23-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 A3L08_07340 1c4688cf5422ee9c2310592a6d469da0 386 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 176 194 3.5E-47 T 23-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 A3L08_07340 1c4688cf5422ee9c2310592a6d469da0 386 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 356 379 3.5E-47 T 23-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 A3L08_07340 1c4688cf5422ee9c2310592a6d469da0 386 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 232 252 3.5E-47 T 23-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 A3L08_07340 1c4688cf5422ee9c2310592a6d469da0 386 Pfam PF04406 Type IIB DNA topoisomerase 83 151 1.1E-18 T 23-10-2018 IPR013049 Spo11/DNA topoisomerase VI, subunit A, N-terminal GO:0003677|GO:0003824|GO:0005524|GO:0005694|GO:0006259 Reactome: R-HSA-912446 A3L08_03530 0f65e6d85e8fb483a66f1d6cea41726d 442 Gene3D G3DSA:3.30.70.1170 180 233 2.1E-9 T 23-10-2018 A3L08_03530 0f65e6d85e8fb483a66f1d6cea41726d 442 TIGRFAM TIGR00446 nop2p: NOL1/NOP2/sun family putative RNA methylase 182 439 4.4E-63 T 23-10-2018 IPR011023 Nop2p GO:0003723|GO:0006364|GO:0008757 Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 A3L08_03530 0f65e6d85e8fb483a66f1d6cea41726d 442 Pfam PF01189 16S rRNA methyltransferase RsmB/F 244 437 5.5E-64 T 23-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 A3L08_03530 0f65e6d85e8fb483a66f1d6cea41726d 442 Gene3D G3DSA:1.10.940.10 1 151 6.4E-41 T 23-10-2018 IPR035926 NusB-like superfamily A3L08_03530 0f65e6d85e8fb483a66f1d6cea41726d 442 Gene3D G3DSA:3.40.50.150 242 442 4.7E-73 T 23-10-2018 A3L08_03530 0f65e6d85e8fb483a66f1d6cea41726d 442 SUPERFAMILY SSF53335 145 440 6.14E-76 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L08_03530 0f65e6d85e8fb483a66f1d6cea41726d 442 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 226 240 7.7E-24 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L08_03530 0f65e6d85e8fb483a66f1d6cea41726d 442 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 323 335 7.7E-24 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L08_03530 0f65e6d85e8fb483a66f1d6cea41726d 442 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 255 265 7.7E-24 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L08_03530 0f65e6d85e8fb483a66f1d6cea41726d 442 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 422 439 7.7E-24 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L08_03530 0f65e6d85e8fb483a66f1d6cea41726d 442 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 373 389 7.7E-24 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L08_03530 0f65e6d85e8fb483a66f1d6cea41726d 442 Pfam PF17125 N-terminal domain of 16S rRNA methyltransferase RsmF 152 214 2.4E-9 T 23-10-2018 IPR031341 Ribosomal RNA small subunit methyltransferase F, N-terminal Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 A3L08_03530 0f65e6d85e8fb483a66f1d6cea41726d 442 Gene3D G3DSA:1.10.287.730 152 177 1.4E-5 T 23-10-2018 A3L08_07040 528cb708410d4137c78783858afb8eaa 580 SUPERFAMILY SSF88802 357 502 9.15E-42 T 23-10-2018 A3L08_07040 528cb708410d4137c78783858afb8eaa 580 Gene3D G3DSA:3.10.450.90 427 501 2.8E-28 T 23-10-2018 IPR038250 TGT, patch-forming C2 domain superfamily MetaCyc: PWY-6711|MetaCyc: PWY-7923 A3L08_07040 528cb708410d4137c78783858afb8eaa 580 SUPERFAMILY SSF51713 4 354 1.09E-115 T 23-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 A3L08_07040 528cb708410d4137c78783858afb8eaa 580 TIGRFAM TIGR00449 tgt_general: tRNA-guanine family transglycosylase 6 338 3.2E-88 T 23-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 A3L08_07040 528cb708410d4137c78783858afb8eaa 580 Pfam PF14810 Patch-forming domain C2 of tRNA-guanine transglycosylase 436 503 1.0E-23 T 23-10-2018 IPR029402 tRNA-guanine transglycosylase, patch-forming domain C2 MetaCyc: PWY-6711|MetaCyc: PWY-7923 A3L08_07040 528cb708410d4137c78783858afb8eaa 580 SMART SM00359 505 579 2.5E-21 T 23-10-2018 IPR002478 PUA domain GO:0003723 A3L08_07040 528cb708410d4137c78783858afb8eaa 580 Pfam PF01702 Queuine tRNA-ribosyltransferase 109 330 1.4E-40 T 23-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 A3L08_07040 528cb708410d4137c78783858afb8eaa 580 Pfam PF14809 C1 domain of tRNA-guanine transglycosylase dimerisation 357 426 3.8E-40 T 23-10-2018 IPR032729 tRNA-guanine(15) transglycosylase, C1 domain MetaCyc: PWY-6711|MetaCyc: PWY-7923 A3L08_07040 528cb708410d4137c78783858afb8eaa 580 SUPERFAMILY SSF88697 504 578 3.54E-21 T 23-10-2018 IPR015947 PUA-like superfamily A3L08_07040 528cb708410d4137c78783858afb8eaa 580 Pfam PF01472 PUA domain 506 577 3.6E-16 T 23-10-2018 IPR002478 PUA domain GO:0003723 A3L08_07040 528cb708410d4137c78783858afb8eaa 580 Gene3D G3DSA:3.90.1020.10 357 426 1.5E-27 T 23-10-2018 IPR038370 TGT, C1 domain superfamily MetaCyc: PWY-6711|MetaCyc: PWY-7923 A3L08_07040 528cb708410d4137c78783858afb8eaa 580 Hamap MF_01634 tRNA-guanine(15) transglycosylase [tgtA]. 6 531 48.465 T 23-10-2018 IPR004804 tRNA-guanine(15) transglycosylase GO:0006400|GO:0016763 MetaCyc: PWY-6711|MetaCyc: PWY-7923 A3L08_07040 528cb708410d4137c78783858afb8eaa 580 Gene3D G3DSA:3.20.20.105 2 356 2.0E-124 T 23-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 A3L08_07040 528cb708410d4137c78783858afb8eaa 580 TIGRFAM TIGR00432 arcsn_tRNA_tgt: tRNA-guanine(15) transglycosylase 6 388 2.0E-170 T 23-10-2018 IPR004804 tRNA-guanine(15) transglycosylase GO:0006400|GO:0016763 MetaCyc: PWY-6711|MetaCyc: PWY-7923 A3L08_07040 528cb708410d4137c78783858afb8eaa 580 TIGRFAM TIGR00451 unchar_dom_2: uncharacterized domain 2 486 575 2.0E-10 T 23-10-2018 IPR004521 Uncharacterised domain CHP00451 GO:0003723 A3L08_07040 528cb708410d4137c78783858afb8eaa 580 Gene3D G3DSA:2.30.130.10 502 579 1.3E-33 T 23-10-2018 IPR036974 PUA domain superfamily GO:0003723 A3L08_02380 3405394085f0d0d9a805b9bcadef11bb 391 Gene3D G3DSA:1.20.1530.20 1 391 4.8E-77 T 23-10-2018 IPR038770 Sodium/solute symporter superfamily A3L08_02380 3405394085f0d0d9a805b9bcadef11bb 391 Pfam PF00999 Sodium/hydrogen exchanger family 9 382 3.3E-56 T 23-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 A3L08_03925 cc55fb085417c694a0ea7106c170a9e5 839 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 525 547 6.8E-9 T 23-10-2018 IPR030934 Intein C-terminal splicing region A3L08_03925 cc55fb085417c694a0ea7106c170a9e5 839 Gene3D G3DSA:3.40.50.300 262 389 2.4E-52 T 23-10-2018 A3L08_03925 cc55fb085417c694a0ea7106c170a9e5 839 PRINTS PR00379 Intein signature 541 550 3.0E-7 T 23-10-2018 IPR006142 Intein GO:0016539 A3L08_03925 cc55fb085417c694a0ea7106c170a9e5 839 PRINTS PR00379 Intein signature 523 540 3.0E-7 T 23-10-2018 IPR006142 Intein GO:0016539 A3L08_03925 cc55fb085417c694a0ea7106c170a9e5 839 PRINTS PR00379 Intein signature 12 24 3.0E-7 T 23-10-2018 IPR006142 Intein GO:0016539 A3L08_03925 cc55fb085417c694a0ea7106c170a9e5 839 SUPERFAMILY SSF52540 547 746 1.92E-29 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_03925 cc55fb085417c694a0ea7106c170a9e5 839 SUPERFAMILY SSF50249 10 247 1.42E-61 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L08_03925 cc55fb085417c694a0ea7106c170a9e5 839 Gene3D G3DSA:2.20.28.10 131 176 2.4E-29 T 23-10-2018 A3L08_03925 cc55fb085417c694a0ea7106c170a9e5 839 TIGRFAM TIGR01445 intein_Nterm: intein N-terminal splicing region 390 480 5.7E-12 T 23-10-2018 IPR006141 Intein N-terminal splicing region GO:0016539 Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A3L08_03925 cc55fb085417c694a0ea7106c170a9e5 839 SUPERFAMILY SSF51294 390 547 1.51E-31 T 23-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A3L08_03925 cc55fb085417c694a0ea7106c170a9e5 839 Gene3D G3DSA:2.170.16.10 390 543 1.5E-35 T 23-10-2018 A3L08_03925 cc55fb085417c694a0ea7106c170a9e5 839 Pfam PF17207 MCM OB domain 104 229 1.6E-35 T 23-10-2018 IPR033762 MCM OB domain Reactome: R-HSA-176187|Reactome: R-HSA-176974|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962 A3L08_03925 cc55fb085417c694a0ea7106c170a9e5 839 Pfam PF14551 MCM N-terminal domain 8 83 2.4E-11 T 23-10-2018 IPR027925 MCM N-terminal domain Reactome: R-HSA-176187|Reactome: R-HSA-176974|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962|Reactome: R-HSA-69052 A3L08_03925 cc55fb085417c694a0ea7106c170a9e5 839 Gene3D G3DSA:3.40.50.300 544 767 4.6E-73 T 23-10-2018 A3L08_03925 cc55fb085417c694a0ea7106c170a9e5 839 Pfam PF14890 Intein splicing domain 397 504 5.1E-11 T 23-10-2018 A3L08_03925 cc55fb085417c694a0ea7106c170a9e5 839 SMART SM00305 506 552 2.9E-11 T 23-10-2018 IPR003586 Hint domain C-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A3L08_03925 cc55fb085417c694a0ea7106c170a9e5 839 Gene3D G3DSA:2.40.50.140 177 256 2.5E-27 T 23-10-2018 A3L08_03925 cc55fb085417c694a0ea7106c170a9e5 839 SMART SM00306 388 504 1.4E-17 T 23-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A3L08_03925 cc55fb085417c694a0ea7106c170a9e5 839 Pfam PF00493 MCM2/3/5 family 547 749 3.4E-80 T 23-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 A3L08_03925 cc55fb085417c694a0ea7106c170a9e5 839 Pfam PF00493 MCM2/3/5 family 265 391 1.8E-50 T 23-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 A3L08_03925 cc55fb085417c694a0ea7106c170a9e5 839 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 615 623 8.3E-22 T 23-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 A3L08_03925 cc55fb085417c694a0ea7106c170a9e5 839 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 564 577 8.3E-22 T 23-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 A3L08_03925 cc55fb085417c694a0ea7106c170a9e5 839 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 588 600 8.3E-22 T 23-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 A3L08_03925 cc55fb085417c694a0ea7106c170a9e5 839 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 319 334 8.3E-22 T 23-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 A3L08_03925 cc55fb085417c694a0ea7106c170a9e5 839 SMART SM00350 100 750 1.7E-168 T 23-10-2018 IPR031327 Mini-chromosome maintenance protein A3L08_03925 cc55fb085417c694a0ea7106c170a9e5 839 Gene3D G3DSA:3.30.1640.10 1 99 7.8E-37 T 23-10-2018 A3L08_03925 cc55fb085417c694a0ea7106c170a9e5 839 SUPERFAMILY SSF52540 288 389 3.19E-12 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_06700 d1187a0d22f6305e7c7b48411951f4f1 333 SUPERFAMILY SSF51735 98 287 2.69E-49 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L08_06700 d1187a0d22f6305e7c7b48411951f4f1 333 Gene3D G3DSA:3.40.50.720 16 318 7.1E-110 T 23-10-2018 A3L08_06700 d1187a0d22f6305e7c7b48411951f4f1 333 SUPERFAMILY SSF52283 1 132 8.13E-33 T 23-10-2018 A3L08_06700 d1187a0d22f6305e7c7b48411951f4f1 333 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 106 286 4.1E-53 T 23-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 A3L08_06700 d1187a0d22f6305e7c7b48411951f4f1 333 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 10 318 4.0E-34 T 23-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 A3L08_06700 d1187a0d22f6305e7c7b48411951f4f1 333 Gene3D G3DSA:3.40.50.720 95 286 7.1E-110 T 23-10-2018 A3L08_06700 d1187a0d22f6305e7c7b48411951f4f1 333 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 149 176 - T 23-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 A3L08_02220 18cd06c07f793144f3d6a7f07e9519cc 423 Pfam PF01882 Protein of unknown function DUF58 203 282 8.8E-22 T 23-10-2018 IPR002881 Domain of unknown function DUF58 A3L08_07840 2b918ebe8c01d2b6823058ef5f73a15e 404 Gene3D G3DSA:3.40.50.10300 187 404 4.3E-70 T 23-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 A3L08_07840 2b918ebe8c01d2b6823058ef5f73a15e 404 SUPERFAMILY SSF52507 18 217 1.31E-47 T 23-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 A3L08_07840 2b918ebe8c01d2b6823058ef5f73a15e 404 Pfam PF02441 Flavoprotein 19 188 3.7E-42 T 23-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 A3L08_07840 2b918ebe8c01d2b6823058ef5f73a15e 404 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 193 374 1.4E-56 T 23-10-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 A3L08_07840 2b918ebe8c01d2b6823058ef5f73a15e 404 Gene3D G3DSA:3.40.50.1950 15 186 4.6E-48 T 23-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 A3L08_07840 2b918ebe8c01d2b6823058ef5f73a15e 404 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 18 400 1.3E-126 T 23-10-2018 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5|MetaCyc: PWY-7851 A3L08_07840 2b918ebe8c01d2b6823058ef5f73a15e 404 SUPERFAMILY SSF102645 180 403 3.53E-66 T 23-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 A3L08_00375 b97ef21da94d51a40ba0adb63c3b13f4 91 TIGRFAM TIGR01300 CPA3_mnhG_phaG: monovalent cation/proton antiporter, MnhG/PhaG subunit 2 86 5.0E-26 T 23-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 A3L08_00375 b97ef21da94d51a40ba0adb63c3b13f4 91 Pfam PF03334 Na+/H+ antiporter subunit 1 73 1.3E-20 T 23-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 A3L08_03950 8d615a189b89665024432f77f87681bb 344 TIGRFAM TIGR03399 RNA_3prim_cycl: RNA 3'-phosphate cyclase 4 325 2.7E-128 T 23-10-2018 IPR017770 RNA 3'-terminal phosphate cyclase type 1 GO:0003963|GO:0006396 A3L08_03950 8d615a189b89665024432f77f87681bb 344 SUPERFAMILY SSF55205 4 216 4.58E-65 T 23-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 A3L08_03950 8d615a189b89665024432f77f87681bb 344 SUPERFAMILY SSF55205 268 331 3.86E-5 T 23-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 A3L08_03950 8d615a189b89665024432f77f87681bb 344 Hamap MF_00200 RNA 3'-terminal phosphate cyclase [rtcA]. 3 338 40.062 T 23-10-2018 IPR017770 RNA 3'-terminal phosphate cyclase type 1 GO:0003963|GO:0006396 A3L08_03950 8d615a189b89665024432f77f87681bb 344 SUPERFAMILY SSF52913 184 279 3.53E-25 T 23-10-2018 IPR036553 RNA 3'-terminal phosphate cyclase, insert domain superfamily A3L08_03950 8d615a189b89665024432f77f87681bb 344 ProSitePatterns PS01287 RNA 3'-terminal phosphate cyclase signature. 154 164 - T 23-10-2018 IPR020719 RNA 3'-terminal phosphate cyclase-like, conserved site A3L08_03950 8d615a189b89665024432f77f87681bb 344 Gene3D G3DSA:3.65.10.20 5 321 8.8E-129 T 23-10-2018 IPR037136 RNA 3'-terminal phosphate cyclase domain superfamily A3L08_03950 8d615a189b89665024432f77f87681bb 344 Pfam PF01137 RNA 3'-terminal phosphate cyclase 10 326 4.3E-77 T 23-10-2018 IPR023797 RNA 3'-terminal phosphate cyclase domain A3L08_03950 8d615a189b89665024432f77f87681bb 344 Pfam PF05189 RNA 3'-terminal phosphate cyclase (RTC), insert domain 182 275 1.6E-23 T 23-10-2018 IPR013791 RNA 3'-terminal phosphate cyclase, insert domain A3L08_03950 8d615a189b89665024432f77f87681bb 344 PIRSF PIRSF005378 1 343 7.8E-113 T 23-10-2018 IPR000228 RNA 3'-terminal phosphate cyclase GO:0006396 A3L08_03950 8d615a189b89665024432f77f87681bb 344 Gene3D G3DSA:3.30.360.20 182 276 8.8E-129 T 23-10-2018 IPR036553 RNA 3'-terminal phosphate cyclase, insert domain superfamily A3L08_02770 8e7ce155dbcdf07231fbb747f1a66b84 422 SUPERFAMILY SSF55031 212 323 3.14E-18 T 23-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain A3L08_02770 8e7ce155dbcdf07231fbb747f1a66b84 422 Gene3D G3DSA:3.30.70.360 214 323 9.1E-18 T 23-10-2018 A3L08_02770 8e7ce155dbcdf07231fbb747f1a66b84 422 SUPERFAMILY SSF53187 5 420 3.02E-62 T 23-10-2018 A3L08_02770 8e7ce155dbcdf07231fbb747f1a66b84 422 TIGRFAM TIGR01910 DapE-ArgE: peptidase, ArgE/DapE family 20 415 2.8E-79 T 23-10-2018 IPR010182 N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine deformylase/Succinyl-diaminopimelate desuccinylase A3L08_02770 8e7ce155dbcdf07231fbb747f1a66b84 422 Gene3D G3DSA:3.40.630.10 9 213 5.8E-43 T 23-10-2018 A3L08_02770 8e7ce155dbcdf07231fbb747f1a66b84 422 Pfam PF01546 Peptidase family M20/M25/M40 97 420 7.3E-37 T 23-10-2018 IPR002933 Peptidase M20 GO:0016787 A3L08_02770 8e7ce155dbcdf07231fbb747f1a66b84 422 Gene3D G3DSA:3.40.630.10 324 422 3.1E-11 T 23-10-2018 A3L08_02770 8e7ce155dbcdf07231fbb747f1a66b84 422 Pfam PF07687 Peptidase dimerisation domain 207 318 6.9E-20 T 23-10-2018 IPR011650 Peptidase M20, dimerisation domain A3L08_06975 61ea42d99a0bbf58f13fe8244e0b9909 498 SUPERFAMILY SSF51445 94 473 1.85E-28 T 23-10-2018 IPR017853 Glycoside hydrolase superfamily A3L08_06975 61ea42d99a0bbf58f13fe8244e0b9909 498 Gene3D G3DSA:3.20.20.80 42 489 1.9E-122 T 23-10-2018 A3L08_06975 61ea42d99a0bbf58f13fe8244e0b9909 498 Pfam PF11790 Glycosyl hydrolase catalytic core 362 449 3.3E-4 T 23-10-2018 IPR024655 Uncharacterised protein family, glycosyl hydrolase catalytic domain A3L08_07205 a963d93a3ebdf446fadc5800660dcb19 88 Hamap MF_00573 50S ribosomal protein L35Ae [rpl35ae]. 4 88 24.477 T 23-10-2018 IPR001780 Ribosomal protein L35A GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_07205 a963d93a3ebdf446fadc5800660dcb19 88 SUPERFAMILY SSF50447 4 87 2.3E-23 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily A3L08_07205 a963d93a3ebdf446fadc5800660dcb19 88 Pfam PF01247 Ribosomal protein L35Ae 4 87 4.5E-15 T 23-10-2018 IPR001780 Ribosomal protein L35A GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_07205 a963d93a3ebdf446fadc5800660dcb19 88 ProDom PD012670 RIBOSOMAL L35A 60S RIBONUCLEOPROTEIN L35A L35AE 50S RNA-BINDING TRNA-BINDING SEQUENCE 5 87 3.0E-30 T 23-10-2018 IPR001780 Ribosomal protein L35A GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_07205 a963d93a3ebdf446fadc5800660dcb19 88 ProSitePatterns PS01105 Ribosomal protein L35Ae signature. 56 77 - T 23-10-2018 IPR018266 Ribosomal protein L35Ae, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_07205 a963d93a3ebdf446fadc5800660dcb19 88 Gene3D G3DSA:2.40.10.190 2 88 1.9E-24 T 23-10-2018 IPR038661 Ribosomal protein L35A superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_02805 f83daedb03301b0da7a8c0440d390e7a 1347 SUPERFAMILY SSF88713 33 577 7.34E-67 T 23-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 A3L08_02805 f83daedb03301b0da7a8c0440d390e7a 1347 Gene3D G3DSA:3.20.110.20 231 504 8.6E-25 T 23-10-2018 A3L08_02805 f83daedb03301b0da7a8c0440d390e7a 1347 Pfam PF09985 C-terminal binding-module, SLH-like, of glucodextranase 1038 1268 3.4E-75 T 23-10-2018 IPR019248 Glucodextranase-like, C-terminal A3L08_02805 f83daedb03301b0da7a8c0440d390e7a 1347 Pfam PF09985 C-terminal binding-module, SLH-like, of glucodextranase 794 1026 7.2E-77 T 23-10-2018 IPR019248 Glucodextranase-like, C-terminal A3L08_02805 f83daedb03301b0da7a8c0440d390e7a 1347 SUPERFAMILY SSF49344 793 1027 7.85E-78 T 23-10-2018 A3L08_02805 f83daedb03301b0da7a8c0440d390e7a 1347 SUPERFAMILY SSF49344 1037 1270 1.88E-75 T 23-10-2018 A3L08_02805 f83daedb03301b0da7a8c0440d390e7a 1347 Pfam PF03065 Glycosyl hydrolase family 57 37 538 3.0E-129 T 23-10-2018 IPR004300 Glycoside hydrolase family 57, N-terminal domain GO:0003824|GO:0005975 A3L08_02805 f83daedb03301b0da7a8c0440d390e7a 1347 TIGRFAM TIGR04288 CGP_CTERM: CGP-CTERM domain 1327 1346 9.7E-7 T 23-10-2018 IPR027552 CGP-CTERM domain A3L08_02805 f83daedb03301b0da7a8c0440d390e7a 1347 Gene3D G3DSA:2.60.40.1190 791 1030 1.7E-62 T 23-10-2018 A3L08_02805 f83daedb03301b0da7a8c0440d390e7a 1347 Gene3D G3DSA:2.60.40.1190 1036 1273 3.0E-62 T 23-10-2018 A3L08_01840 007f10aa3926038593adefea971357df 330 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 18 321 4.1E-123 T 23-10-2018 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00450+1.8.1.9 A3L08_01840 007f10aa3926038593adefea971357df 330 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 154 174 - T 23-10-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 A3L08_01840 007f10aa3926038593adefea971357df 330 Gene3D G3DSA:3.50.50.60 136 257 1.7E-117 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L08_01840 007f10aa3926038593adefea971357df 330 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 19 310 7.1E-61 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A3L08_01840 007f10aa3926038593adefea971357df 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 285 303 3.4E-67 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A3L08_01840 007f10aa3926038593adefea971357df 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 125 133 3.4E-67 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A3L08_01840 007f10aa3926038593adefea971357df 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 72 82 3.4E-67 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A3L08_01840 007f10aa3926038593adefea971357df 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 19 41 3.4E-67 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A3L08_01840 007f10aa3926038593adefea971357df 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 51 66 3.4E-67 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A3L08_01840 007f10aa3926038593adefea971357df 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 147 159 3.4E-67 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A3L08_01840 007f10aa3926038593adefea971357df 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 162 186 3.4E-67 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A3L08_01840 007f10aa3926038593adefea971357df 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 213 229 3.4E-67 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A3L08_01840 007f10aa3926038593adefea971357df 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 251 272 3.4E-67 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A3L08_01840 007f10aa3926038593adefea971357df 330 SUPERFAMILY SSF51905 15 320 1.43E-62 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L08_01840 007f10aa3926038593adefea971357df 330 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 275 297 4.9E-41 T 23-10-2018 A3L08_01840 007f10aa3926038593adefea971357df 330 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 20 39 4.9E-41 T 23-10-2018 A3L08_01840 007f10aa3926038593adefea971357df 330 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 249 265 4.9E-41 T 23-10-2018 A3L08_01840 007f10aa3926038593adefea971357df 330 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 124 142 4.9E-41 T 23-10-2018 A3L08_01840 007f10aa3926038593adefea971357df 330 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 166 184 4.9E-41 T 23-10-2018 A3L08_01840 007f10aa3926038593adefea971357df 330 Gene3D G3DSA:3.50.50.60 18 315 1.7E-117 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L08_04095 ba20572caf0e6d574310267d4dbeb033 111 Gene3D G3DSA:2.40.50.1000 1 111 5.2E-39 T 23-10-2018 A3L08_04095 ba20572caf0e6d574310267d4dbeb033 111 ProSitePatterns PS00056 Ribosomal protein S17 signature. 82 94 - T 23-10-2018 IPR019979 Ribosomal protein S17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_04095 ba20572caf0e6d574310267d4dbeb033 111 Hamap MF_01345_A 30S ribosomal protein S17 [rpsQ]. 2 106 33.505 T 23-10-2018 IPR019978 Ribosomal protein S17, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L08_04095 ba20572caf0e6d574310267d4dbeb033 111 PRINTS PR00973 Ribosomal protein S17 family signature 49 72 3.5E-11 T 23-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L08_04095 ba20572caf0e6d574310267d4dbeb033 111 PRINTS PR00973 Ribosomal protein S17 family signature 82 92 3.5E-11 T 23-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L08_04095 ba20572caf0e6d574310267d4dbeb033 111 PRINTS PR00973 Ribosomal protein S17 family signature 92 99 3.5E-11 T 23-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L08_04095 ba20572caf0e6d574310267d4dbeb033 111 Pfam PF00366 Ribosomal protein S17 35 102 2.1E-27 T 23-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L08_04095 ba20572caf0e6d574310267d4dbeb033 111 SUPERFAMILY SSF50249 29 109 6.85E-29 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L08_04095 ba20572caf0e6d574310267d4dbeb033 111 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 31 102 2.0E-32 T 23-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L08_04095 ba20572caf0e6d574310267d4dbeb033 111 TIGRFAM TIGR03630 uS17_arch: ribosomal protein uS17 4 104 1.0E-47 T 23-10-2018 IPR028333 Ribosomal protein S17, archaeal/eukaryotic Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_02500 5c1a2651a6674bb7dd19b2307bc5d127 591 PIRSF PIRSF005669 1 573 4.5E-249 T 23-10-2018 IPR034687 Elongator complex protein 3-like Reactome: R-HSA-3214847 A3L08_02500 5c1a2651a6674bb7dd19b2307bc5d127 591 Gene3D G3DSA:3.80.30.20 232 382 1.0E-12 T 23-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe A3L08_02500 5c1a2651a6674bb7dd19b2307bc5d127 591 SUPERFAMILY SSF102114 84 381 4.32E-35 T 23-10-2018 A3L08_02500 5c1a2651a6674bb7dd19b2307bc5d127 591 Pfam PF04055 Radical SAM superfamily 86 319 7.5E-31 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L08_02500 5c1a2651a6674bb7dd19b2307bc5d127 591 TIGRFAM TIGR01211 ELP3: radical SAM enzyme/protein acetyltransferase, ELP3 family 13 572 3.8E-263 T 23-10-2018 IPR034687 Elongator complex protein 3-like Reactome: R-HSA-3214847 A3L08_02500 5c1a2651a6674bb7dd19b2307bc5d127 591 Pfam PF16199 Radical_SAM C-terminal domain 335 414 1.1E-26 T 23-10-2018 IPR032432 Radical SAM, C-terminal extension Reactome: R-HSA-3214847 A3L08_02500 5c1a2651a6674bb7dd19b2307bc5d127 591 Gene3D G3DSA:3.40.630.30 419 573 1.8E-8 T 23-10-2018 A3L08_02500 5c1a2651a6674bb7dd19b2307bc5d127 591 SMART SM00729 79 374 3.5E-49 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A3L08_02500 5c1a2651a6674bb7dd19b2307bc5d127 591 Pfam PF00583 Acetyltransferase (GNAT) family 449 561 1.5E-8 T 23-10-2018 IPR000182 GNAT domain A3L08_02500 5c1a2651a6674bb7dd19b2307bc5d127 591 SUPERFAMILY SSF55729 445 567 1.18E-10 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase A3L08_02195 af0155b3f638f933a5f26c1aed3734c8 163 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 3 147 1.2E-22 T 23-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain A3L08_02195 af0155b3f638f933a5f26c1aed3734c8 163 SUPERFAMILY SSF54534 2 150 8.05E-49 T 23-10-2018 A3L08_02195 af0155b3f638f933a5f26c1aed3734c8 163 Gene3D G3DSA:3.10.50.80 2 157 1.1E-55 T 23-10-2018 A3L08_00575 a781eda9fbb61a480f777f121b96103a 213 Pfam PF01914 MarC family integral membrane protein 6 211 3.9E-61 T 23-10-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 A3L08_00575 a781eda9fbb61a480f777f121b96103a 213 TIGRFAM TIGR00427 TIGR00427: membrane protein, MarC family 4 207 4.7E-63 T 23-10-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 A3L08_06460 aa0804de9b695c4a26181773b25589cf 143 SUPERFAMILY SSF88723 1 132 1.15E-19 T 23-10-2018 IPR029060 PIN-like domain superfamily A3L08_06460 aa0804de9b695c4a26181773b25589cf 143 Gene3D G3DSA:3.40.50.1010 3 137 3.0E-17 T 23-10-2018 A3L08_06460 aa0804de9b695c4a26181773b25589cf 143 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 4 139 10.117 T 23-10-2018 IPR022907 VapC family GO:0004540 A3L08_06460 aa0804de9b695c4a26181773b25589cf 143 SMART SM00670 2 131 7.7E-16 T 23-10-2018 IPR002716 PIN domain A3L08_06460 aa0804de9b695c4a26181773b25589cf 143 Pfam PF01850 PIN domain 4 133 4.6E-22 T 23-10-2018 IPR002716 PIN domain A3L08_04570 e64ffa567605e683283485c4f1104859 383 SUPERFAMILY SSF53187 7 382 2.63E-87 T 23-10-2018 A3L08_04570 e64ffa567605e683283485c4f1104859 383 SUPERFAMILY SSF55031 185 287 4.32E-31 T 23-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain A3L08_04570 e64ffa567605e683283485c4f1104859 383 PIRSF PIRSF005962 1 383 3.7E-135 T 23-10-2018 IPR017439 Amidohydrolase GO:0016787 A3L08_04570 e64ffa567605e683283485c4f1104859 383 Gene3D G3DSA:3.40.630.10 16 367 5.0E-145 T 23-10-2018 A3L08_04570 e64ffa567605e683283485c4f1104859 383 Pfam PF01546 Peptidase family M20/M25/M40 70 373 9.2E-37 T 23-10-2018 IPR002933 Peptidase M20 GO:0016787 A3L08_04570 e64ffa567605e683283485c4f1104859 383 Pfam PF07687 Peptidase dimerisation domain 187 278 2.1E-11 T 23-10-2018 IPR011650 Peptidase M20, dimerisation domain A3L08_04570 e64ffa567605e683283485c4f1104859 383 Gene3D G3DSA:3.30.70.360 178 292 5.0E-145 T 23-10-2018 A3L08_04570 e64ffa567605e683283485c4f1104859 383 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 16 370 1.1E-118 T 23-10-2018 IPR017439 Amidohydrolase GO:0016787 A3L08_02565 47f55c0416c6e4e4cb72472995f9ddc5 230 Gene3D G3DSA:3.30.70.1450 141 222 8.4E-16 T 23-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 A3L08_02565 47f55c0416c6e4e4cb72472995f9ddc5 230 SUPERFAMILY SSF116726 135 220 2.22E-12 T 23-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 A3L08_02565 47f55c0416c6e4e4cb72472995f9ddc5 230 SUPERFAMILY SSF51735 1 144 1.81E-37 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L08_02565 47f55c0416c6e4e4cb72472995f9ddc5 230 Pfam PF02254 TrkA-N domain 3 124 1.3E-28 T 23-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 A3L08_02565 47f55c0416c6e4e4cb72472995f9ddc5 230 Gene3D G3DSA:3.40.50.720 1 140 2.8E-41 T 23-10-2018 A3L08_02565 47f55c0416c6e4e4cb72472995f9ddc5 230 PRINTS PR00335 TrkA potassium uptake protein signature 2 16 2.2E-13 T 23-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 A3L08_02565 47f55c0416c6e4e4cb72472995f9ddc5 230 PRINTS PR00335 TrkA potassium uptake protein signature 60 70 2.2E-13 T 23-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 A3L08_02565 47f55c0416c6e4e4cb72472995f9ddc5 230 PRINTS PR00335 TrkA potassium uptake protein signature 73 87 2.2E-13 T 23-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 A3L08_02565 47f55c0416c6e4e4cb72472995f9ddc5 230 PRINTS PR00335 TrkA potassium uptake protein signature 19 33 2.2E-13 T 23-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 A3L08_02565 47f55c0416c6e4e4cb72472995f9ddc5 230 PRINTS PR00335 TrkA potassium uptake protein signature 49 59 2.2E-13 T 23-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 A3L08_02565 47f55c0416c6e4e4cb72472995f9ddc5 230 Pfam PF02080 TrkA-C domain 153 217 3.4E-12 T 23-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A3L08_07770 560629aab15f67974faf2494078bc1c8 326 Gene3D G3DSA:3.30.460.20 1 136 1.5E-22 T 23-10-2018 A3L08_07770 560629aab15f67974faf2494078bc1c8 326 Pfam PF01544 CorA-like Mg2+ transporter protein 39 322 3.3E-64 T 23-10-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 A3L08_07770 560629aab15f67974faf2494078bc1c8 326 SUPERFAMILY SSF143865 2 259 9.02E-58 T 23-10-2018 A3L08_07770 560629aab15f67974faf2494078bc1c8 326 Gene3D G3DSA:1.20.58.340 137 247 5.3E-31 T 23-10-2018 A3L08_07770 560629aab15f67974faf2494078bc1c8 326 TIGRFAM TIGR00383 corA: magnesium and cobalt transport protein CorA 10 326 2.5E-80 T 23-10-2018 IPR004488 Magnesium/cobalt transport protein CorA GO:0006824|GO:0015087|GO:0015095|GO:0015693|GO:0016020 A3L08_07770 560629aab15f67974faf2494078bc1c8 326 SUPERFAMILY SSF144083 261 323 1.57E-21 T 23-10-2018 A3L08_07770 560629aab15f67974faf2494078bc1c8 326 Gene3D G3DSA:1.20.58.340 249 326 2.4E-32 T 23-10-2018 A3L08_02815 e69640dc49c2340eff8a523a6ed173f4 301 SUPERFAMILY SSF160964 6 42 4.32E-7 T 23-10-2018 A3L08_02815 e69640dc49c2340eff8a523a6ed173f4 301 SUPERFAMILY SSF161098 60 286 7.72E-50 T 23-10-2018 IPR035906 MetI-like superfamily A3L08_02815 e69640dc49c2340eff8a523a6ed173f4 301 Gene3D G3DSA:1.10.3720.10 56 298 3.0E-58 T 23-10-2018 IPR035906 MetI-like superfamily A3L08_02815 e69640dc49c2340eff8a523a6ed173f4 301 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 91 285 4.3E-18 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A3L08_01380 2039de1e30a859417196cdafd21b687d 296 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 228 241 - T 23-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 A3L08_01380 2039de1e30a859417196cdafd21b687d 296 SUPERFAMILY SSF53613 1 278 1.23E-63 T 23-10-2018 IPR029056 Ribokinase-like A3L08_01380 2039de1e30a859417196cdafd21b687d 296 Pfam PF00294 pfkB family carbohydrate kinase 6 273 3.1E-42 T 23-10-2018 IPR011611 Carbohydrate kinase PfkB A3L08_01380 2039de1e30a859417196cdafd21b687d 296 Gene3D G3DSA:3.40.1190.20 4 288 1.9E-61 T 23-10-2018 IPR029056 Ribokinase-like A3L08_01380 2039de1e30a859417196cdafd21b687d 296 PRINTS PR00990 Ribokinase signature 8 29 1.8E-7 T 23-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A3L08_01380 2039de1e30a859417196cdafd21b687d 296 PRINTS PR00990 Ribokinase signature 105 118 1.8E-7 T 23-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A3L08_01380 2039de1e30a859417196cdafd21b687d 296 PRINTS PR00990 Ribokinase signature 166 181 1.8E-7 T 23-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A3L08_01380 2039de1e30a859417196cdafd21b687d 296 PRINTS PR00990 Ribokinase signature 198 209 1.8E-7 T 23-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A3L08_01380 2039de1e30a859417196cdafd21b687d 296 PRINTS PR00990 Ribokinase signature 35 54 1.8E-7 T 23-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A3L08_07385 339bae06ce6a834b46fa8668e6fb1706 102 Pfam PF00338 Ribosomal protein S10p/S20e 5 98 5.8E-28 T 23-10-2018 IPR027486 Ribosomal protein S10 domain A3L08_07385 339bae06ce6a834b46fa8668e6fb1706 102 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 1 100 25.008 T 23-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_07385 339bae06ce6a834b46fa8668e6fb1706 102 ProSitePatterns PS00361 Ribosomal protein S10 signature. 27 42 - T 23-10-2018 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_07385 339bae06ce6a834b46fa8668e6fb1706 102 SMART SM01403 5 99 3.0E-41 T 23-10-2018 IPR027486 Ribosomal protein S10 domain A3L08_07385 339bae06ce6a834b46fa8668e6fb1706 102 Gene3D G3DSA:3.30.70.600 1 101 6.2E-35 T 23-10-2018 IPR036838 Ribosomal protein S10 domain superfamily A3L08_07385 339bae06ce6a834b46fa8668e6fb1706 102 SUPERFAMILY SSF54999 3 100 2.62E-29 T 23-10-2018 IPR036838 Ribosomal protein S10 domain superfamily A3L08_07385 339bae06ce6a834b46fa8668e6fb1706 102 PRINTS PR00971 Ribosomal protein S10 family signature 3 16 5.1E-17 T 23-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_07385 339bae06ce6a834b46fa8668e6fb1706 102 PRINTS PR00971 Ribosomal protein S10 family signature 60 74 5.1E-17 T 23-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_07385 339bae06ce6a834b46fa8668e6fb1706 102 PRINTS PR00971 Ribosomal protein S10 family signature 38 53 5.1E-17 T 23-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_07385 339bae06ce6a834b46fa8668e6fb1706 102 TIGRFAM TIGR01046 uS10_euk_arch: ribosomal protein uS10 2 100 4.0E-50 T 23-10-2018 IPR005729 Ribosomal protein S10, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_02695 3a0c162ca386f430bf2fcf3d367c8b03 441 SMART SM01230 98 341 2.3E-134 T 23-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A3L08_02695 3a0c162ca386f430bf2fcf3d367c8b03 441 SUPERFAMILY SSF54368 18 97 3.66E-19 T 23-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A3L08_02695 3a0c162ca386f430bf2fcf3d367c8b03 441 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 224 239 - T 23-10-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 A3L08_02695 3a0c162ca386f430bf2fcf3d367c8b03 441 Pfam PF00120 Glutamine synthetase, catalytic domain 99 437 1.6E-128 T 23-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A3L08_02695 3a0c162ca386f430bf2fcf3d367c8b03 441 ProSitePatterns PS00180 Glutamine synthetase signature 1. 50 68 - T 23-10-2018 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 A3L08_02695 3a0c162ca386f430bf2fcf3d367c8b03 441 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 18 92 4.1E-20 T 23-10-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 A3L08_02695 3a0c162ca386f430bf2fcf3d367c8b03 441 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 136 439 6.2E-134 T 23-10-2018 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A3L08_02695 3a0c162ca386f430bf2fcf3d367c8b03 441 Gene3D G3DSA:3.10.20.70 5 100 1.0E-22 T 23-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A3L08_02695 3a0c162ca386f430bf2fcf3d367c8b03 441 SUPERFAMILY SSF55931 100 440 2.06E-122 T 23-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 A3L08_02695 3a0c162ca386f430bf2fcf3d367c8b03 441 Gene3D G3DSA:3.30.590.10 101 441 1.1E-127 T 23-10-2018 A3L08_02445 5b705a5dba1e1797dbb49010d4892c82 436 TIGRFAM TIGR00443 hisZ_biosyn_reg: ATP phosphoribosyltransferase, regulatory subunit 11 326 5.7E-87 T 23-10-2018 IPR004517 ATP phosphoribosyltransferase regulatory subunit GO:0000105|GO:0005737 A3L08_02445 5b705a5dba1e1797dbb49010d4892c82 436 Pfam PF13393 Histidyl-tRNA synthetase 9 323 4.5E-67 T 23-10-2018 A3L08_02445 5b705a5dba1e1797dbb49010d4892c82 436 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 6 422 2.3E-127 T 23-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 A3L08_02445 5b705a5dba1e1797dbb49010d4892c82 436 SUPERFAMILY SSF52954 331 434 3.47E-24 T 23-10-2018 A3L08_02445 5b705a5dba1e1797dbb49010d4892c82 436 Hamap MF_00125 ATP phosphoribosyltransferase regulatory subunit [hisZ]. 16 385 26.556 T 23-10-2018 IPR004517 ATP phosphoribosyltransferase regulatory subunit GO:0000105|GO:0005737 A3L08_02445 5b705a5dba1e1797dbb49010d4892c82 436 Gene3D G3DSA:3.30.930.10 1 328 5.3E-111 T 23-10-2018 A3L08_02445 5b705a5dba1e1797dbb49010d4892c82 436 Gene3D G3DSA:3.40.50.800 338 432 2.0E-25 T 23-10-2018 IPR036621 Anticodon-binding domain superfamily A3L08_02445 5b705a5dba1e1797dbb49010d4892c82 436 PIRSF PIRSF001549 1 432 1.5E-140 T 23-10-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 A3L08_02445 5b705a5dba1e1797dbb49010d4892c82 436 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 2 432 31.1 T 23-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 A3L08_02445 5b705a5dba1e1797dbb49010d4892c82 436 SUPERFAMILY SSF55681 6 331 9.36E-87 T 23-10-2018 A3L08_02445 5b705a5dba1e1797dbb49010d4892c82 436 Pfam PF03129 Anticodon binding domain 341 431 3.5E-21 T 23-10-2018 IPR004154 Anticodon-binding A3L08_08565 8831609de8747a05fa9d638eca855270 451 PRINTS PR00149 Fumarate lyase superfamily signature 227 254 2.0E-27 T 23-10-2018 IPR000362 Fumarate lyase family A3L08_08565 8831609de8747a05fa9d638eca855270 451 PRINTS PR00149 Fumarate lyase superfamily signature 96 114 2.0E-27 T 23-10-2018 IPR000362 Fumarate lyase family A3L08_08565 8831609de8747a05fa9d638eca855270 451 PRINTS PR00149 Fumarate lyase superfamily signature 141 159 2.0E-27 T 23-10-2018 IPR000362 Fumarate lyase family A3L08_08565 8831609de8747a05fa9d638eca855270 451 PRINTS PR00149 Fumarate lyase superfamily signature 272 288 2.0E-27 T 23-10-2018 IPR000362 Fumarate lyase family A3L08_08565 8831609de8747a05fa9d638eca855270 451 ProSitePatterns PS00163 Fumarate lyases signature. 272 281 - T 23-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 A3L08_08565 8831609de8747a05fa9d638eca855270 451 Gene3D G3DSA:1.10.275.10 1 100 1.4E-37 T 23-10-2018 IPR024083 Fumarase/histidase, N-terminal A3L08_08565 8831609de8747a05fa9d638eca855270 451 Pfam PF00206 Lyase 13 293 7.2E-59 T 23-10-2018 IPR022761 Fumarate lyase, N-terminal A3L08_08565 8831609de8747a05fa9d638eca855270 451 SMART SM00998 360 439 2.9E-33 T 23-10-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A3L08_08565 8831609de8747a05fa9d638eca855270 451 Gene3D G3DSA:1.10.40.30 360 439 4.0E-24 T 23-10-2018 A3L08_08565 8831609de8747a05fa9d638eca855270 451 Pfam PF10397 Adenylosuccinate lyase C-terminus 362 438 3.3E-20 T 23-10-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A3L08_08565 8831609de8747a05fa9d638eca855270 451 Gene3D G3DSA:1.20.200.10 101 359 1.9E-96 T 23-10-2018 A3L08_08565 8831609de8747a05fa9d638eca855270 451 SUPERFAMILY SSF48557 4 442 1.12E-135 T 23-10-2018 IPR008948 L-Aspartase-like GO:0003824 A3L08_08565 8831609de8747a05fa9d638eca855270 451 PRINTS PR00145 Argininosuccinate lyase family signature 272 288 1.7E-11 T 23-10-2018 A3L08_08565 8831609de8747a05fa9d638eca855270 451 PRINTS PR00145 Argininosuccinate lyase family signature 136 156 1.7E-11 T 23-10-2018 A3L08_08565 8831609de8747a05fa9d638eca855270 451 PRINTS PR00145 Argininosuccinate lyase family signature 227 251 1.7E-11 T 23-10-2018 A3L08_08565 8831609de8747a05fa9d638eca855270 451 PRINTS PR00145 Argininosuccinate lyase family signature 95 117 1.7E-11 T 23-10-2018 A3L08_08565 8831609de8747a05fa9d638eca855270 451 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 6 438 2.7E-188 T 23-10-2018 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A3L08_06270 c7cce78e40648e6e93b91c313a0c17b7 376 PIRSF PIRSF005357 1 346 3.2E-116 T 23-10-2018 IPR007152 Protein of unknown function DUF354 A3L08_06270 c7cce78e40648e6e93b91c313a0c17b7 376 Pfam PF04007 Protein of unknown function (DUF354) 1 338 2.7E-99 T 23-10-2018 IPR007152 Protein of unknown function DUF354 A3L08_06270 c7cce78e40648e6e93b91c313a0c17b7 376 SUPERFAMILY SSF53756 1 319 2.39E-23 T 23-10-2018 A3L08_08350 c7ef674078b46e4240077313b4fd05cb 174 Gene3D G3DSA:3.40.630.30 1 143 1.1E-62 T 23-10-2018 A3L08_08350 c7ef674078b46e4240077313b4fd05cb 174 Pfam PF00583 Acetyltransferase (GNAT) family 46 159 1.6E-19 T 23-10-2018 IPR000182 GNAT domain A3L08_08350 c7ef674078b46e4240077313b4fd05cb 174 SUPERFAMILY SSF55729 14 168 3.06E-27 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase A3L08_08350 c7ef674078b46e4240077313b4fd05cb 174 Gene3D G3DSA:3.30.1990.20 144 174 3.7E-11 T 23-10-2018 A3L08_07240 4fc7aaa4d8c9698e51c27579964718be 75 Pfam PF04023 FeoA domain 3 73 6.1E-20 T 23-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 A3L08_07240 4fc7aaa4d8c9698e51c27579964718be 75 Gene3D G3DSA:2.30.30.90 12 75 2.4E-21 T 23-10-2018 IPR038157 Ferrous iron transporter, core domain A3L08_07240 4fc7aaa4d8c9698e51c27579964718be 75 SMART SM00899 3 74 5.3E-20 T 23-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 A3L08_07240 4fc7aaa4d8c9698e51c27579964718be 75 SUPERFAMILY SSF50037 5 74 1.58E-17 T 23-10-2018 IPR008988 Transcriptional repressor, C-terminal A3L08_08765 121648fa64208e7751daf91686cf9fc3 62 Pfam PF01904 Protein of unknown function DUF72 15 58 2.0E-14 T 23-10-2018 IPR002763 Protein of unknown function DUF72 A3L08_08765 121648fa64208e7751daf91686cf9fc3 62 SUPERFAMILY SSF117396 1 58 8.24E-19 T 23-10-2018 IPR036520 UPF0759 superfamily A3L08_08765 121648fa64208e7751daf91686cf9fc3 62 Gene3D G3DSA:3.20.20.410 1 59 8.2E-15 T 23-10-2018 IPR036520 UPF0759 superfamily A3L08_00465 cc9daed211accd41fdbca05f01b3dafc 646 TIGRFAM TIGR03336 IOR_alpha: indolepyruvate ferredoxin oxidoreductase, alpha subunit 16 638 9.4E-266 T 23-10-2018 IPR017721 Indolepyruvate ferredoxin oxidoreductase, alpha subunit GO:0043805|GO:0055114 A3L08_00465 cc9daed211accd41fdbca05f01b3dafc 646 SUPERFAMILY SSF54862 582 640 5.45E-14 T 23-10-2018 A3L08_00465 cc9daed211accd41fdbca05f01b3dafc 646 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 28 209 4.1E-15 T 23-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 A3L08_00465 cc9daed211accd41fdbca05f01b3dafc 646 PIRSF PIRSF006439 5 645 1.6E-258 T 23-10-2018 IPR017721 Indolepyruvate ferredoxin oxidoreductase, alpha subunit GO:0043805|GO:0055114 A3L08_00465 cc9daed211accd41fdbca05f01b3dafc 646 SUPERFAMILY SSF52518 380 599 4.64E-33 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold A3L08_00465 cc9daed211accd41fdbca05f01b3dafc 646 Gene3D G3DSA:3.30.70.20 568 640 3.5E-11 T 23-10-2018 A3L08_00465 cc9daed211accd41fdbca05f01b3dafc 646 SUPERFAMILY SSF52922 249 355 7.26E-7 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A3L08_00465 cc9daed211accd41fdbca05f01b3dafc 646 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 410 562 4.4E-30 T 23-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 A3L08_00465 cc9daed211accd41fdbca05f01b3dafc 646 Pfam PF12838 4Fe-4S dicluster domain 591 637 1.2E-6 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L08_00465 cc9daed211accd41fdbca05f01b3dafc 646 Gene3D G3DSA:3.40.50.970 5 196 1.2E-53 T 23-10-2018 A3L08_00465 cc9daed211accd41fdbca05f01b3dafc 646 SUPERFAMILY SSF52518 14 246 3.24E-57 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold A3L08_00465 cc9daed211accd41fdbca05f01b3dafc 646 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 623 634 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L08_00465 cc9daed211accd41fdbca05f01b3dafc 646 Gene3D G3DSA:3.40.50.970 392 567 2.9E-21 T 23-10-2018 A3L08_06890 86e63f490fa09dea855b878887c3dfd0 428 Gene3D G3DSA:3.40.1190.20 1 251 2.5E-70 T 23-10-2018 IPR029056 Ribokinase-like A3L08_06890 86e63f490fa09dea855b878887c3dfd0 428 Pfam PF10120 Thiamine-phosphate synthase 258 423 2.2E-55 T 23-10-2018 IPR019293 Thiamine-phosphate synthase ThiN GO:0004789 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A3L08_06890 86e63f490fa09dea855b878887c3dfd0 428 Pfam PF08543 Phosphomethylpyrimidine kinase 10 235 4.2E-70 T 23-10-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 A3L08_06890 86e63f490fa09dea855b878887c3dfd0 428 SUPERFAMILY SSF53613 3 237 4.83E-56 T 23-10-2018 IPR029056 Ribokinase-like A3L08_06890 86e63f490fa09dea855b878887c3dfd0 428 SUPERFAMILY SSF53639 252 425 2.79E-56 T 23-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily A3L08_06890 86e63f490fa09dea855b878887c3dfd0 428 Gene3D G3DSA:3.40.225.10 252 427 8.6E-65 T 23-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily A3L08_06890 86e63f490fa09dea855b878887c3dfd0 428 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 3 232 5.8E-66 T 23-10-2018 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A3L08_07795 c0f0511fbb7f9ad510dcf76d8879a9f6 177 Pfam PF02441 Flavoprotein 1 156 9.8E-30 T 23-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 A3L08_07795 c0f0511fbb7f9ad510dcf76d8879a9f6 177 SUPERFAMILY SSF52507 1 176 5.23E-60 T 23-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 A3L08_07795 c0f0511fbb7f9ad510dcf76d8879a9f6 177 Gene3D G3DSA:3.40.50.1950 1 177 7.6E-75 T 23-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 A3L08_07795 c0f0511fbb7f9ad510dcf76d8879a9f6 177 Hamap MF_01984 Flavin prenyltransferase UbiX [ubiX]. 1 177 38.0 T 23-10-2018 IPR004507 Flavin prenyltransferase UbiX-like A3L08_07795 c0f0511fbb7f9ad510dcf76d8879a9f6 177 TIGRFAM TIGR00421 ubiX_pad: polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylases 2 175 2.9E-73 T 23-10-2018 IPR004507 Flavin prenyltransferase UbiX-like A3L08_00760 159df4de06bb53c0f9be866aaa91591a 482 Gene3D G3DSA:1.10.1060.10 3 152 3.1E-39 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 A3L08_00760 159df4de06bb53c0f9be866aaa91591a 482 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 23 141 1.7E-38 T 23-10-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 A3L08_00760 159df4de06bb53c0f9be866aaa91591a 482 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 159 459 7.5E-42 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A3L08_00760 159df4de06bb53c0f9be866aaa91591a 482 Gene3D G3DSA:3.50.50.60 268 408 3.8E-46 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L08_00760 159df4de06bb53c0f9be866aaa91591a 482 SUPERFAMILY SSF51971 159 408 2.77E-71 T 23-10-2018 A3L08_00760 159df4de06bb53c0f9be866aaa91591a 482 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 400 416 2.7E-22 T 23-10-2018 A3L08_00760 159df4de06bb53c0f9be866aaa91591a 482 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 298 316 2.7E-22 T 23-10-2018 A3L08_00760 159df4de06bb53c0f9be866aaa91591a 482 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 160 179 2.7E-22 T 23-10-2018 A3L08_00760 159df4de06bb53c0f9be866aaa91591a 482 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 428 450 2.7E-22 T 23-10-2018 A3L08_00760 159df4de06bb53c0f9be866aaa91591a 482 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 243 261 2.7E-22 T 23-10-2018 A3L08_00760 159df4de06bb53c0f9be866aaa91591a 482 SUPERFAMILY SSF46548 10 168 1.26E-31 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 A3L08_00760 159df4de06bb53c0f9be866aaa91591a 482 TIGRFAM TIGR01316 gltA: glutamate synthase (NADPH), homotetrameric 19 474 2.3E-219 T 23-10-2018 IPR006004 Glutamate synthase (NADPH), homotetrameric KEGG: 00195+1.18.1.2|MetaCyc: PWY-101 A3L08_00760 159df4de06bb53c0f9be866aaa91591a 482 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 298 323 3.6E-16 T 23-10-2018 A3L08_00760 159df4de06bb53c0f9be866aaa91591a 482 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 401 415 3.6E-16 T 23-10-2018 A3L08_00760 159df4de06bb53c0f9be866aaa91591a 482 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 443 450 3.6E-16 T 23-10-2018 A3L08_00760 159df4de06bb53c0f9be866aaa91591a 482 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 159 181 3.6E-16 T 23-10-2018 A3L08_00760 159df4de06bb53c0f9be866aaa91591a 482 SUPERFAMILY SSF51971 341 474 2.47E-13 T 23-10-2018 A3L08_00760 159df4de06bb53c0f9be866aaa91591a 482 Gene3D G3DSA:3.40.50.720 155 267 2.5E-25 T 23-10-2018 A3L08_07430 6093bdb3bd5129fe25c62dd97c58f1a1 436 PIRSF PIRSF009445 1 435 5.7E-197 T 23-10-2018 IPR016557 Cyclic 2, 3-diphospoglycerate synthetase GO:0005737|GO:0006094|GO:0036356 A3L08_07430 6093bdb3bd5129fe25c62dd97c58f1a1 436 Hamap MF_01908 Cyclic 2,3-diphosphoglycerate synthetase [cpgS]. 1 434 49.38 T 23-10-2018 IPR016557 Cyclic 2, 3-diphospoglycerate synthetase GO:0005737|GO:0006094|GO:0036356 A3L08_07430 6093bdb3bd5129fe25c62dd97c58f1a1 436 Gene3D G3DSA:3.40.50.300 191 320 4.9E-6 T 23-10-2018 A3L08_08815 07337a2dfdd082392b7c41cd2f66866a 123 PRINTS PR00881 Ribosomal protein L7A/RS6 family signature 32 46 1.6E-22 T 23-10-2018 IPR018492 Ribosomal protein L7Ae/L8/Nhp2 family A3L08_08815 07337a2dfdd082392b7c41cd2f66866a 123 PRINTS PR00881 Ribosomal protein L7A/RS6 family signature 67 77 1.6E-22 T 23-10-2018 IPR018492 Ribosomal protein L7Ae/L8/Nhp2 family A3L08_08815 07337a2dfdd082392b7c41cd2f66866a 123 PRINTS PR00881 Ribosomal protein L7A/RS6 family signature 77 91 1.6E-22 T 23-10-2018 IPR018492 Ribosomal protein L7Ae/L8/Nhp2 family A3L08_08815 07337a2dfdd082392b7c41cd2f66866a 123 PRINTS PR00881 Ribosomal protein L7A/RS6 family signature 51 64 1.6E-22 T 23-10-2018 IPR018492 Ribosomal protein L7Ae/L8/Nhp2 family A3L08_08815 07337a2dfdd082392b7c41cd2f66866a 123 PRINTS PR00884 Ribosomal protein HS6 signature 50 61 2.7E-31 T 23-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L08_08815 07337a2dfdd082392b7c41cd2f66866a 123 PRINTS PR00884 Ribosomal protein HS6 signature 77 87 2.7E-31 T 23-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L08_08815 07337a2dfdd082392b7c41cd2f66866a 123 PRINTS PR00884 Ribosomal protein HS6 signature 91 107 2.7E-31 T 23-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L08_08815 07337a2dfdd082392b7c41cd2f66866a 123 PRINTS PR00884 Ribosomal protein HS6 signature 6 17 2.7E-31 T 23-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L08_08815 07337a2dfdd082392b7c41cd2f66866a 123 PRINTS PR00884 Ribosomal protein HS6 signature 40 50 2.7E-31 T 23-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L08_08815 07337a2dfdd082392b7c41cd2f66866a 123 SUPERFAMILY SSF55315 4 120 1.62E-40 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like A3L08_08815 07337a2dfdd082392b7c41cd2f66866a 123 TIGRFAM TIGR03677 eL8_ribo: ribosomal protein eL8 6 121 2.3E-58 T 23-10-2018 IPR022481 Ribosomal protein L7Ae, archaea GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L08_08815 07337a2dfdd082392b7c41cd2f66866a 123 Gene3D G3DSA:3.30.1330.30 1 123 1.6E-43 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like A3L08_08815 07337a2dfdd082392b7c41cd2f66866a 123 Hamap MF_00326 50S ribosomal protein L7Ae [rpl7ae]. 3 122 35.506 T 23-10-2018 IPR022481 Ribosomal protein L7Ae, archaea GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L08_08815 07337a2dfdd082392b7c41cd2f66866a 123 Pfam PF01248 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family 18 110 5.0E-33 T 23-10-2018 IPR004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45 A3L08_08815 07337a2dfdd082392b7c41cd2f66866a 123 ProSitePatterns PS01082 Ribosomal protein L7Ae signature. 70 87 - T 23-10-2018 IPR004037 Ribosomal protein L7Ae conserved site GO:0042254|GO:1990904 Reactome: R-HSA-6791226 A3L08_03890 8bfb3cf7ddcf5f4e59e8625f81518e24 336 SUPERFAMILY SSF51735 3 176 2.64E-29 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L08_03890 8bfb3cf7ddcf5f4e59e8625f81518e24 336 Gene3D G3DSA:3.40.50.720 6 327 1.7E-95 T 23-10-2018 A3L08_03890 8bfb3cf7ddcf5f4e59e8625f81518e24 336 Gene3D G3DSA:3.30.360.10 167 310 1.7E-95 T 23-10-2018 A3L08_03890 8bfb3cf7ddcf5f4e59e8625f81518e24 336 PIRSF PIRSF036497 1 335 2.0E-88 T 23-10-2018 IPR022697 Homoserine dehydrogenase lacking ACT domain GO:0004412 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 A3L08_03890 8bfb3cf7ddcf5f4e59e8625f81518e24 336 SUPERFAMILY SSF55347 156 314 1.11E-37 T 23-10-2018 A3L08_03890 8bfb3cf7ddcf5f4e59e8625f81518e24 336 Pfam PF00742 Homoserine dehydrogenase 156 327 6.7E-47 T 23-10-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 A3L08_03890 8bfb3cf7ddcf5f4e59e8625f81518e24 336 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 10 148 4.3E-10 T 23-10-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 A3L08_03890 8bfb3cf7ddcf5f4e59e8625f81518e24 336 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 201 223 - T 23-10-2018 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 A3L08_07960 a73ae068876f9f15ea97cdfbcce8269f 636 SMART SM00926 1 53 3.4E-8 T 23-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L08_07960 a73ae068876f9f15ea97cdfbcce8269f 636 Gene3D G3DSA:2.40.40.20 517 636 7.3E-29 T 23-10-2018 A3L08_07960 a73ae068876f9f15ea97cdfbcce8269f 636 ProSitePatterns PS00932 Prokaryotic molybdopterin oxidoreductases signature 3. 558 585 - T 23-10-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 A3L08_07960 a73ae068876f9f15ea97cdfbcce8269f 636 SUPERFAMILY SSF53706 3 525 2.22E-142 T 23-10-2018 A3L08_07960 a73ae068876f9f15ea97cdfbcce8269f 636 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 4 47 2.1E-7 T 23-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L08_07960 a73ae068876f9f15ea97cdfbcce8269f 636 Gene3D G3DSA:3.30.2070.10 407 487 2.5E-125 T 23-10-2018 A3L08_07960 a73ae068876f9f15ea97cdfbcce8269f 636 Gene3D G3DSA:2.20.25.90 2 58 1.6E-8 T 23-10-2018 A3L08_07960 a73ae068876f9f15ea97cdfbcce8269f 636 Gene3D G3DSA:3.40.228.10 133 505 2.5E-125 T 23-10-2018 A3L08_07960 a73ae068876f9f15ea97cdfbcce8269f 636 Pfam PF01568 Molydopterin dinucleotide binding domain 525 629 3.5E-21 T 23-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 A3L08_07960 a73ae068876f9f15ea97cdfbcce8269f 636 SUPERFAMILY SSF50692 516 636 3.39E-33 T 23-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily A3L08_07960 a73ae068876f9f15ea97cdfbcce8269f 636 Gene3D G3DSA:3.40.50.740 67 450 2.5E-125 T 23-10-2018 A3L08_07960 a73ae068876f9f15ea97cdfbcce8269f 636 Pfam PF00384 Molybdopterin oxidoreductase 56 427 2.3E-49 T 23-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L08_03195 83986878b96419b97d7c7da7c3901830 466 Pfam PF00890 FAD binding domain 6 348 4.5E-66 T 23-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A3L08_03195 83986878b96419b97d7c7da7c3901830 466 SUPERFAMILY SSF56425 205 309 5.08E-33 T 23-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 A3L08_03195 83986878b96419b97d7c7da7c3901830 466 Gene3D G3DSA:3.50.50.60 6 355 1.4E-110 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L08_03195 83986878b96419b97d7c7da7c3901830 466 TIGRFAM TIGR00551 nadB: L-aspartate oxidase 3 447 5.5E-154 T 23-10-2018 IPR005288 L-aspartate oxidase GO:0005737|GO:0008734|GO:0009435|GO:0055114 KEGG: 00250+1.4.3.16|KEGG: 00760+1.4.3.16|MetaCyc: PWY-5316|MetaCyc: PWY-7342 A3L08_03195 83986878b96419b97d7c7da7c3901830 466 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 321 339 1.0E-6 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A3L08_03195 83986878b96419b97d7c7da7c3901830 466 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 3 25 1.0E-6 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A3L08_03195 83986878b96419b97d7c7da7c3901830 466 SUPERFAMILY SSF46977 386 451 2.22E-18 T 23-10-2018 IPR037099 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A3L08_03195 83986878b96419b97d7c7da7c3901830 466 Pfam PF02910 Fumarate reductase flavoprotein C-term 423 448 1.2E-5 T 23-10-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A3L08_03195 83986878b96419b97d7c7da7c3901830 466 Gene3D G3DSA:1.20.58.100 370 461 1.4E-17 T 23-10-2018 A3L08_03195 83986878b96419b97d7c7da7c3901830 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 5.2E-11 T 23-10-2018 A3L08_03195 83986878b96419b97d7c7da7c3901830 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 311 333 5.2E-11 T 23-10-2018 A3L08_03195 83986878b96419b97d7c7da7c3901830 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 164 182 5.2E-11 T 23-10-2018 A3L08_03195 83986878b96419b97d7c7da7c3901830 466 SUPERFAMILY SSF51905 6 384 2.25E-47 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L08_03195 83986878b96419b97d7c7da7c3901830 466 Gene3D G3DSA:3.90.700.10 213 303 1.4E-110 T 23-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 A3L08_05940 395939eb271a4a4e86252816fd7c791c 483 Hamap MF_00028 Cobyric acid synthase [cobQ]. 1 483 163.583 T 23-10-2018 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 A3L08_05940 395939eb271a4a4e86252816fd7c791c 483 SUPERFAMILY SSF52540 1 236 1.49E-49 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_05940 395939eb271a4a4e86252816fd7c791c 483 TIGRFAM TIGR00313 cobQ: cobyric acid synthase CobQ 5 476 6.1E-159 T 23-10-2018 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 A3L08_05940 395939eb271a4a4e86252816fd7c791c 483 Gene3D G3DSA:3.40.50.880 248 401 1.6E-16 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A3L08_05940 395939eb271a4a4e86252816fd7c791c 483 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 250 432 1.3E-50 T 23-10-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 A3L08_05940 395939eb271a4a4e86252816fd7c791c 483 Gene3D G3DSA:3.40.50.300 2 241 7.5E-50 T 23-10-2018 A3L08_05940 395939eb271a4a4e86252816fd7c791c 483 SUPERFAMILY SSF52317 192 389 3.97E-28 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A3L08_05940 395939eb271a4a4e86252816fd7c791c 483 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 5 229 1.5E-20 T 23-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain A3L08_00550 ce34cc3829938fff7b272bcc537385e3 322 Gene3D G3DSA:3.40.50.10470 115 310 2.8E-84 T 23-10-2018 A3L08_00550 ce34cc3829938fff7b272bcc537385e3 322 SUPERFAMILY SSF100950 4 311 2.99E-101 T 23-10-2018 IPR037171 NagB/RpiA transferase-like A3L08_00550 ce34cc3829938fff7b272bcc537385e3 322 TIGRFAM TIGR00511 ribulose_e2b2: ribose-1,5-bisphosphate isomerase, e2b2 family 6 312 8.6E-149 T 23-10-2018 IPR005250 Ribose-1,5-bisphosphate isomerase, e2b2 family MetaCyc: PWY-5532 A3L08_00550 ce34cc3829938fff7b272bcc537385e3 322 Gene3D G3DSA:1.20.120.420 1 114 2.9E-46 T 23-10-2018 IPR027363 Methylthioribose-1-phosphate isomerase, N-terminal KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 A3L08_00550 ce34cc3829938fff7b272bcc537385e3 322 TIGRFAM TIGR00524 eIF-2B_rel: eIF-2B alpha/beta/delta-related uncharacterized proteins 5 299 1.0E-97 T 23-10-2018 IPR011559 Initiation factor 2B alpha/beta/delta GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 A3L08_00550 ce34cc3829938fff7b272bcc537385e3 322 Pfam PF01008 Initiation factor 2 subunit family 19 299 3.6E-93 T 23-10-2018 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 A3L08_01735 65edb6aba15644ed30980800f5512c34 167 PIRSF PIRSF019239 1 165 3.5E-40 T 23-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 A3L08_01735 65edb6aba15644ed30980800f5512c34 167 Pfam PF01899 Na+/H+ ion antiporter subunit 7 164 2.9E-42 T 23-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 A3L08_06970 3c2b7d2efe829d5460b3ccd7d4160ab2 384 TIGRFAM TIGR04288 CGP_CTERM: CGP-CTERM domain 364 383 1.0E-7 T 23-10-2018 IPR027552 CGP-CTERM domain A3L08_06970 3c2b7d2efe829d5460b3ccd7d4160ab2 384 Gene3D G3DSA:2.60.120.180 46 309 2.4E-39 T 23-10-2018 IPR013319 Glycoside hydrolase family 11/12 GO:0004553 MetaCyc: PWY-6717|MetaCyc: PWY-6784 A3L08_03705 9d57910b390072e81e60155272e323c9 451 Gene3D G3DSA:3.40.50.150 154 450 2.0E-79 T 23-10-2018 A3L08_03705 9d57910b390072e81e60155272e323c9 451 Pfam PF01189 16S rRNA methyltransferase RsmB/F 255 449 2.4E-48 T 23-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 A3L08_03705 9d57910b390072e81e60155272e323c9 451 Gene3D G3DSA:1.10.940.10 6 151 4.3E-14 T 23-10-2018 IPR035926 NusB-like superfamily A3L08_03705 9d57910b390072e81e60155272e323c9 451 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 237 251 4.0E-21 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L08_03705 9d57910b390072e81e60155272e323c9 451 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 381 397 4.0E-21 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L08_03705 9d57910b390072e81e60155272e323c9 451 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 433 450 4.0E-21 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L08_03705 9d57910b390072e81e60155272e323c9 451 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 331 343 4.0E-21 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L08_03705 9d57910b390072e81e60155272e323c9 451 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 266 276 4.0E-21 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L08_03705 9d57910b390072e81e60155272e323c9 451 SUPERFAMILY SSF48013 9 163 2.49E-24 T 23-10-2018 IPR035926 NusB-like superfamily A3L08_03705 9d57910b390072e81e60155272e323c9 451 SUPERFAMILY SSF53335 147 450 1.25E-71 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L08_03705 9d57910b390072e81e60155272e323c9 451 Pfam PF01029 NusB family 10 133 3.7E-19 T 23-10-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 A3L08_05210 dcb601b9aafcb7b1a3d368e048636c5b 314 Pfam PF00753 Metallo-beta-lactamase superfamily 18 76 6.3E-10 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L08_05210 dcb601b9aafcb7b1a3d368e048636c5b 314 Gene3D G3DSA:3.60.15.10 1 299 4.3E-84 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L08_05210 dcb601b9aafcb7b1a3d368e048636c5b 314 Hamap MF_01818 Ribonuclease BN [rbn]. 2 299 34.731 T 23-10-2018 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 A3L08_05210 dcb601b9aafcb7b1a3d368e048636c5b 314 Pfam PF12706 Beta-lactamase superfamily domain 187 263 1.7E-7 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L08_05210 dcb601b9aafcb7b1a3d368e048636c5b 314 SMART SM00849 19 207 2.5E-5 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L08_05210 dcb601b9aafcb7b1a3d368e048636c5b 314 TIGRFAM TIGR02651 RNase_Z: ribonuclease Z 3 295 5.9E-99 T 23-10-2018 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 A3L08_05210 dcb601b9aafcb7b1a3d368e048636c5b 314 SUPERFAMILY SSF56281 3 298 1.65E-75 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L08_04850 8b60dba3bbe8408ee2449b6b65a7dc05 424 Pfam PF02310 B12 binding domain 18 109 2.9E-9 T 23-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 A3L08_04850 8b60dba3bbe8408ee2449b6b65a7dc05 424 SMART SM00729 164 382 1.8E-46 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A3L08_04850 8b60dba3bbe8408ee2449b6b65a7dc05 424 Gene3D G3DSA:3.40.50.280 3 126 1.3E-25 T 23-10-2018 A3L08_04850 8b60dba3bbe8408ee2449b6b65a7dc05 424 SUPERFAMILY SSF102114 155 376 2.35E-38 T 23-10-2018 A3L08_04850 8b60dba3bbe8408ee2449b6b65a7dc05 424 Pfam PF04055 Radical SAM superfamily 168 338 4.1E-24 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L08_04850 8b60dba3bbe8408ee2449b6b65a7dc05 424 TIGRFAM TIGR04013 B12_SAM_MJ_1487: B12-binding domain/radical SAM domain protein, MJ_1487 family 4 392 4.9E-142 T 23-10-2018 IPR023980 Conserved hypothetical protein CHP04013, B12-binding/radical SAM-type A3L08_04850 8b60dba3bbe8408ee2449b6b65a7dc05 424 Gene3D G3DSA:3.80.30.20 163 389 3.2E-36 T 23-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe A3L08_03190 7ee06225e4689e84f133b6734bf37be7 485 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 291 303 - T 23-10-2018 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 A3L08_03190 7ee06225e4689e84f133b6734bf37be7 485 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 14 452 1.3E-192 T 23-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 A3L08_03190 7ee06225e4689e84f133b6734bf37be7 485 SMART SM00116 102 149 1.7E-10 T 23-10-2018 IPR000644 CBS domain A3L08_03190 7ee06225e4689e84f133b6734bf37be7 485 SMART SM00116 159 207 2.9E-16 T 23-10-2018 IPR000644 CBS domain A3L08_03190 7ee06225e4689e84f133b6734bf37be7 485 Gene3D G3DSA:3.20.20.70 4 483 1.2E-200 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L08_03190 7ee06225e4689e84f133b6734bf37be7 485 Pfam PF00571 CBS domain 152 205 4.7E-17 T 23-10-2018 IPR000644 CBS domain A3L08_03190 7ee06225e4689e84f133b6734bf37be7 485 Pfam PF00571 CBS domain 100 145 1.9E-11 T 23-10-2018 IPR000644 CBS domain A3L08_03190 7ee06225e4689e84f133b6734bf37be7 485 SMART SM01240 13 470 2.1E-267 T 23-10-2018 A3L08_03190 7ee06225e4689e84f133b6734bf37be7 485 PIRSF PIRSF000130 3 485 8.9E-198 T 23-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 A3L08_03190 7ee06225e4689e84f133b6734bf37be7 485 SUPERFAMILY SSF51412 10 474 1.16E-112 T 23-10-2018 A3L08_03190 7ee06225e4689e84f133b6734bf37be7 485 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 14 483 81.132 T 23-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 A3L08_03190 7ee06225e4689e84f133b6734bf37be7 485 SUPERFAMILY SSF54631 94 204 3.79E-33 T 23-10-2018 A3L08_03190 7ee06225e4689e84f133b6734bf37be7 485 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 14 470 5.4E-149 T 23-10-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 A3L08_05365 f0fbf478cce1e6c546b108e8246c5c58 399 Gene3D G3DSA:3.90.1150.10 7 387 1.8E-147 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A3L08_05365 f0fbf478cce1e6c546b108e8246c5c58 399 Pfam PF00266 Aminotransferase class-V 18 386 1.9E-140 T 23-10-2018 IPR000192 Aminotransferase class V domain A3L08_05365 f0fbf478cce1e6c546b108e8246c5c58 399 PIRSF PIRSF005572 15 399 1.4E-51 T 23-10-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 A3L08_05365 f0fbf478cce1e6c546b108e8246c5c58 399 Gene3D G3DSA:3.40.640.10 29 287 1.8E-147 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A3L08_05365 f0fbf478cce1e6c546b108e8246c5c58 399 SUPERFAMILY SSF53383 5 397 5.38E-120 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A3L08_04810 f8c6ee9174e8746779ba2c369eb5dbb8 152 Gene3D G3DSA:3.30.70.940 2 87 3.4E-34 T 23-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 A3L08_04810 f8c6ee9174e8746779ba2c369eb5dbb8 152 TIGRFAM TIGR00405 KOW_elon_Spt5: transcription elongation factor Spt5 7 150 2.4E-51 T 23-10-2018 IPR011590 Transcription elongation factor Spt5, archaeal GO:0003746 A3L08_04810 f8c6ee9174e8746779ba2c369eb5dbb8 152 SUPERFAMILY SSF50104 54 147 2.82E-17 T 23-10-2018 IPR008991 Translation protein SH3-like domain superfamily A3L08_04810 f8c6ee9174e8746779ba2c369eb5dbb8 152 SMART SM00738 3 87 5.4E-20 T 23-10-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 A3L08_04810 f8c6ee9174e8746779ba2c369eb5dbb8 152 Pfam PF03439 Early transcription elongation factor of RNA pol II, NGN section 5 84 4.4E-24 T 23-10-2018 IPR005100 NGN domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 A3L08_04810 f8c6ee9174e8746779ba2c369eb5dbb8 152 SMART SM00739 92 119 1.2E-6 T 23-10-2018 IPR005824 KOW A3L08_04810 f8c6ee9174e8746779ba2c369eb5dbb8 152 Gene3D G3DSA:2.30.30.30 88 152 1.6E-27 T 23-10-2018 IPR014722 Ribosomal protein L2, domain 2 A3L08_04810 f8c6ee9174e8746779ba2c369eb5dbb8 152 Hamap MF_00950 Transcription elongation factor Spt5 [spt5]. 5 148 38.318 T 23-10-2018 IPR011590 Transcription elongation factor Spt5, archaeal GO:0003746 A3L08_04810 f8c6ee9174e8746779ba2c369eb5dbb8 152 Pfam PF00467 KOW motif 95 126 2.3E-8 T 23-10-2018 IPR005824 KOW A3L08_08930 deebda70b1dfaabf8c8bbd02e4e3800e 263 SUPERFAMILY SSF52540 2 220 2.25E-63 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_08930 deebda70b1dfaabf8c8bbd02e4e3800e 263 Gene3D G3DSA:3.40.50.300 1 245 2.5E-69 T 23-10-2018 A3L08_08930 deebda70b1dfaabf8c8bbd02e4e3800e 263 Pfam PF00005 ABC transporter 27 162 8.2E-30 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L08_08930 deebda70b1dfaabf8c8bbd02e4e3800e 263 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L08_08930 deebda70b1dfaabf8c8bbd02e4e3800e 263 SMART SM00382 26 211 2.9E-14 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L08_01120 3ae7aafe008c6f24a29edab81e8c3c5c 451 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 151 246 8.1E-20 T 23-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L08_01120 3ae7aafe008c6f24a29edab81e8c3c5c 451 SUPERFAMILY SSF53738 3 170 6.67E-47 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L08_01120 3ae7aafe008c6f24a29edab81e8c3c5c 451 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 254 357 2.1E-19 T 23-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L08_01120 3ae7aafe008c6f24a29edab81e8c3c5c 451 Gene3D G3DSA:3.30.310.50 360 451 1.8E-22 T 23-10-2018 A3L08_01120 3ae7aafe008c6f24a29edab81e8c3c5c 451 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 89 103 2.6E-14 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L08_01120 3ae7aafe008c6f24a29edab81e8c3c5c 451 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 226 241 2.6E-14 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L08_01120 3ae7aafe008c6f24a29edab81e8c3c5c 451 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 165 184 2.6E-14 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L08_01120 3ae7aafe008c6f24a29edab81e8c3c5c 451 SUPERFAMILY SSF53738 150 249 4.32E-24 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L08_01120 3ae7aafe008c6f24a29edab81e8c3c5c 451 Gene3D G3DSA:3.40.120.10 166 345 1.5E-54 T 23-10-2018 A3L08_01120 3ae7aafe008c6f24a29edab81e8c3c5c 451 Hamap MF_01554_A Phosphoglucosamine mutase [glmM]. 2 446 52.502 T 23-10-2018 IPR023666 Phosphoglucosamine mutase, archaeal GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L08_01120 3ae7aafe008c6f24a29edab81e8c3c5c 451 SUPERFAMILY SSF55957 348 448 4.19E-24 T 23-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L08_01120 3ae7aafe008c6f24a29edab81e8c3c5c 451 TIGRFAM TIGR03990 Arch_GlmM: phosphoglucosamine mutase 3 441 5.0E-165 T 23-10-2018 IPR024086 Phosphoglucosamine mutase, archaeal type GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L08_01120 3ae7aafe008c6f24a29edab81e8c3c5c 451 SUPERFAMILY SSF53738 252 355 5.3E-23 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L08_01120 3ae7aafe008c6f24a29edab81e8c3c5c 451 Gene3D G3DSA:3.40.120.10 247 330 1.5E-54 T 23-10-2018 A3L08_01120 3ae7aafe008c6f24a29edab81e8c3c5c 451 Gene3D G3DSA:3.40.120.10 1 147 1.4E-52 T 23-10-2018 A3L08_01120 3ae7aafe008c6f24a29edab81e8c3c5c 451 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 90 99 - T 23-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L08_01120 3ae7aafe008c6f24a29edab81e8c3c5c 451 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 3 132 9.3E-46 T 23-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L08_01120 3ae7aafe008c6f24a29edab81e8c3c5c 451 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 366 440 1.8E-7 T 23-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L08_00335 2136a85d86b9dd5ca58dc1c257fc4c2e 481 Gene3D G3DSA:1.10.1060.10 4 151 4.4E-39 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 A3L08_00335 2136a85d86b9dd5ca58dc1c257fc4c2e 481 TIGRFAM TIGR01316 gltA: glutamate synthase (NADPH), homotetrameric 18 472 8.9E-208 T 23-10-2018 IPR006004 Glutamate synthase (NADPH), homotetrameric KEGG: 00195+1.18.1.2|MetaCyc: PWY-101 A3L08_00335 2136a85d86b9dd5ca58dc1c257fc4c2e 481 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 441 448 6.8E-18 T 23-10-2018 A3L08_00335 2136a85d86b9dd5ca58dc1c257fc4c2e 481 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 401 415 6.8E-18 T 23-10-2018 A3L08_00335 2136a85d86b9dd5ca58dc1c257fc4c2e 481 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 159 181 6.8E-18 T 23-10-2018 A3L08_00335 2136a85d86b9dd5ca58dc1c257fc4c2e 481 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 298 323 6.8E-18 T 23-10-2018 A3L08_00335 2136a85d86b9dd5ca58dc1c257fc4c2e 481 Gene3D G3DSA:3.50.50.60 294 481 2.4E-30 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L08_00335 2136a85d86b9dd5ca58dc1c257fc4c2e 481 Gene3D G3DSA:3.50.50.60 154 286 3.2E-37 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L08_00335 2136a85d86b9dd5ca58dc1c257fc4c2e 481 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 159 457 4.4E-39 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A3L08_00335 2136a85d86b9dd5ca58dc1c257fc4c2e 481 SUPERFAMILY SSF51971 378 473 5.89E-15 T 23-10-2018 A3L08_00335 2136a85d86b9dd5ca58dc1c257fc4c2e 481 SUPERFAMILY SSF51971 157 408 1.94E-70 T 23-10-2018 A3L08_00335 2136a85d86b9dd5ca58dc1c257fc4c2e 481 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 22 140 2.5E-38 T 23-10-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 A3L08_00335 2136a85d86b9dd5ca58dc1c257fc4c2e 481 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 400 416 8.4E-24 T 23-10-2018 A3L08_00335 2136a85d86b9dd5ca58dc1c257fc4c2e 481 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 298 316 8.4E-24 T 23-10-2018 A3L08_00335 2136a85d86b9dd5ca58dc1c257fc4c2e 481 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 426 448 8.4E-24 T 23-10-2018 A3L08_00335 2136a85d86b9dd5ca58dc1c257fc4c2e 481 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 160 179 8.4E-24 T 23-10-2018 A3L08_00335 2136a85d86b9dd5ca58dc1c257fc4c2e 481 SUPERFAMILY SSF46548 7 168 8.89E-32 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 A3L08_06705 5ebaf09ec458573efae4400a95eebdb7 331 Gene3D G3DSA:3.40.630.10 8 324 1.8E-114 T 23-10-2018 A3L08_06705 5ebaf09ec458573efae4400a95eebdb7 331 SUPERFAMILY SSF53187 2 330 1.38E-54 T 23-10-2018 A3L08_06705 5ebaf09ec458573efae4400a95eebdb7 331 Gene3D G3DSA:2.40.30.40 64 155 1.8E-114 T 23-10-2018 IPR023367 Peptidase M42, domain 2 A3L08_06705 5ebaf09ec458573efae4400a95eebdb7 331 SUPERFAMILY SSF101821 65 172 1.34E-21 T 23-10-2018 A3L08_06705 5ebaf09ec458573efae4400a95eebdb7 331 PIRSF PIRSF001123 1 331 2.0E-88 T 23-10-2018 IPR008007 Peptidase M42 A3L08_06705 5ebaf09ec458573efae4400a95eebdb7 331 Pfam PF05343 M42 glutamyl aminopeptidase 42 323 2.6E-86 T 23-10-2018 IPR008007 Peptidase M42 A3L08_08725 629122500bfc5439d69169d8a97f0458 324 Pfam PF02915 Rubrerythrin 25 159 6.6E-21 T 23-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 A3L08_08725 629122500bfc5439d69169d8a97f0458 324 SUPERFAMILY SSF47240 19 165 4.56E-27 T 23-10-2018 IPR009078 Ferritin-like superfamily A3L08_08725 629122500bfc5439d69169d8a97f0458 324 Gene3D G3DSA:1.20.1260.10 15 163 3.7E-32 T 23-10-2018 IPR012347 Ferritin-like A3L08_08725 629122500bfc5439d69169d8a97f0458 324 Pfam PF05763 Protein of unknown function (DUF835) 183 320 2.3E-29 T 23-10-2018 IPR008553 Domain of unknown function DUF835 A3L08_05575 547242dcf657ee419fd5b746dc48faed 626 SUPERFAMILY SSF55681 207 489 1.83E-57 T 23-10-2018 A3L08_05575 547242dcf657ee419fd5b746dc48faed 626 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 288 492 2.0E-18 T 23-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L08_05575 547242dcf657ee419fd5b746dc48faed 626 Gene3D G3DSA:3.40.50.800 504 607 9.9E-35 T 23-10-2018 IPR036621 Anticodon-binding domain superfamily A3L08_05575 547242dcf657ee419fd5b746dc48faed 626 Gene3D G3DSA:3.50.80.10 1 139 2.9E-58 T 23-10-2018 IPR023509 D-aminoacyl-tRNA deacylase-like superfamily A3L08_05575 547242dcf657ee419fd5b746dc48faed 626 SUPERFAMILY SSF52954 504 606 1.22E-32 T 23-10-2018 A3L08_05575 547242dcf657ee419fd5b746dc48faed 626 Gene3D G3DSA:3.30.930.10 203 494 1.8E-61 T 23-10-2018 A3L08_05575 547242dcf657ee419fd5b746dc48faed 626 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 35 602 29.161 T 23-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A3L08_05575 547242dcf657ee419fd5b746dc48faed 626 PRINTS PR01047 Threonyl-tRNA synthetase signature 428 456 1.6E-32 T 23-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A3L08_05575 547242dcf657ee419fd5b746dc48faed 626 PRINTS PR01047 Threonyl-tRNA synthetase signature 506 518 1.6E-32 T 23-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A3L08_05575 547242dcf657ee419fd5b746dc48faed 626 PRINTS PR01047 Threonyl-tRNA synthetase signature 471 484 1.6E-32 T 23-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A3L08_05575 547242dcf657ee419fd5b746dc48faed 626 PRINTS PR01047 Threonyl-tRNA synthetase signature 294 322 1.6E-32 T 23-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A3L08_05575 547242dcf657ee419fd5b746dc48faed 626 PRINTS PR01047 Threonyl-tRNA synthetase signature 328 351 1.6E-32 T 23-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A3L08_05575 547242dcf657ee419fd5b746dc48faed 626 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 28 603 2.1E-174 T 23-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A3L08_05575 547242dcf657ee419fd5b746dc48faed 626 Pfam PF08915 Archaea-specific editing domain of threonyl-tRNA synthetase 1 139 7.7E-57 T 23-10-2018 IPR015011 Threonyl-tRNA synthetase, editing domain, archaea GO:0004829|GO:0005524|GO:0005737|GO:0008270 KEGG: 00970+6.1.1.3 A3L08_05575 547242dcf657ee419fd5b746dc48faed 626 Pfam PF03129 Anticodon binding domain 513 602 7.1E-26 T 23-10-2018 IPR004154 Anticodon-binding A3L08_05575 547242dcf657ee419fd5b746dc48faed 626 ProDom PD016189 SYNTHETASE LIGASE THREONYL-TRNA AMINOACYL-TRNA NUCLEOTIDE-BINDING BIOSYNTHESIS ATP-BINDING ZINC METAL-BINDING THRRS 1 139 1.0E-61 T 23-10-2018 IPR015011 Threonyl-tRNA synthetase, editing domain, archaea GO:0004829|GO:0005524|GO:0005737|GO:0008270 KEGG: 00970+6.1.1.3 A3L08_09455 14e433a4717cc77810692645136e904e 299 Gene3D G3DSA:1.10.472.170 6 197 5.7E-68 T 23-10-2018 A3L08_09455 14e433a4717cc77810692645136e904e 299 Pfam PF08271 TFIIB zinc-binding 6 47 1.4E-18 T 23-10-2018 IPR013137 Zinc finger, TFIIB-type A3L08_09455 14e433a4717cc77810692645136e904e 299 Pfam PF00382 Transcription factor TFIIB repeat 212 282 2.0E-23 T 23-10-2018 IPR013150 Transcription factor TFIIB, cyclin-like domain GO:0017025 A3L08_09455 14e433a4717cc77810692645136e904e 299 Pfam PF00382 Transcription factor TFIIB repeat 117 186 3.2E-20 T 23-10-2018 IPR013150 Transcription factor TFIIB, cyclin-like domain GO:0017025 A3L08_09455 14e433a4717cc77810692645136e904e 299 PRINTS PR00685 Transcription initiation factor IIB signature 245 261 8.2E-62 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 A3L08_09455 14e433a4717cc77810692645136e904e 299 PRINTS PR00685 Transcription initiation factor IIB signature 182 197 8.2E-62 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 A3L08_09455 14e433a4717cc77810692645136e904e 299 PRINTS PR00685 Transcription initiation factor IIB signature 54 75 8.2E-62 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 A3L08_09455 14e433a4717cc77810692645136e904e 299 PRINTS PR00685 Transcription initiation factor IIB signature 277 291 8.2E-62 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 A3L08_09455 14e433a4717cc77810692645136e904e 299 PRINTS PR00685 Transcription initiation factor IIB signature 19 39 8.2E-62 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 A3L08_09455 14e433a4717cc77810692645136e904e 299 PRINTS PR00685 Transcription initiation factor IIB signature 41 54 8.2E-62 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 A3L08_09455 14e433a4717cc77810692645136e904e 299 PRINTS PR00685 Transcription initiation factor IIB signature 156 175 8.2E-62 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 A3L08_09455 14e433a4717cc77810692645136e904e 299 PRINTS PR00685 Transcription initiation factor IIB signature 211 229 8.2E-62 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 A3L08_09455 14e433a4717cc77810692645136e904e 299 SUPERFAMILY SSF47954 113 200 9.92E-28 T 23-10-2018 IPR036915 Cyclin-like superfamily A3L08_09455 14e433a4717cc77810692645136e904e 299 SUPERFAMILY SSF57783 3 50 3.74E-17 T 23-10-2018 A3L08_09455 14e433a4717cc77810692645136e904e 299 ProSitePatterns PS00782 Transcription factor TFIIB repeat signature. 244 259 - T 23-10-2018 IPR023486 Transcription factor TFIIB, conserved site Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-674695|Reactome: R-HSA-6807505|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-76042 A3L08_09455 14e433a4717cc77810692645136e904e 299 ProSitePatterns PS00782 Transcription factor TFIIB repeat signature. 148 163 - T 23-10-2018 IPR023486 Transcription factor TFIIB, conserved site Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-674695|Reactome: R-HSA-6807505|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-76042 A3L08_09455 14e433a4717cc77810692645136e904e 299 SUPERFAMILY SSF47954 206 298 1.75E-30 T 23-10-2018 IPR036915 Cyclin-like superfamily A3L08_09455 14e433a4717cc77810692645136e904e 299 Gene3D G3DSA:1.10.472.10 207 299 2.5E-29 T 23-10-2018 A3L08_09455 14e433a4717cc77810692645136e904e 299 Hamap MF_00383 Transcription initiation factor IIB [tfb]. 1 297 44.633 T 23-10-2018 IPR023484 Transcription initiation factor TFIIB, archaea A3L08_09455 14e433a4717cc77810692645136e904e 299 SMART SM00385 114 195 6.9E-12 T 23-10-2018 IPR013763 Cyclin-like A3L08_09455 14e433a4717cc77810692645136e904e 299 SMART SM00385 210 291 3.2E-14 T 23-10-2018 IPR013763 Cyclin-like A3L08_03405 e0d208876b13815c417134bb3b27e995 182 Pfam PF06510 Protein of unknown function (DUF1102) 37 178 2.6E-50 T 23-10-2018 IPR009482 Protein of unknown function DUF1102 A3L08_04065 697943a60c37de8eb99c4dccb45d58ef 133 PRINTS PR00975 Ribosomal protein S19 family signature 66 85 2.2E-19 T 23-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_04065 697943a60c37de8eb99c4dccb45d58ef 133 PRINTS PR00975 Ribosomal protein S19 family signature 86 98 2.2E-19 T 23-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_04065 697943a60c37de8eb99c4dccb45d58ef 133 PRINTS PR00975 Ribosomal protein S19 family signature 98 113 2.2E-19 T 23-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_04065 697943a60c37de8eb99c4dccb45d58ef 133 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 33 122 25.713 T 23-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_04065 697943a60c37de8eb99c4dccb45d58ef 133 Pfam PF00203 Ribosomal protein S19 35 116 1.1E-35 T 23-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_04065 697943a60c37de8eb99c4dccb45d58ef 133 PIRSF PIRSF002144 1 133 1.7E-40 T 23-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_04065 697943a60c37de8eb99c4dccb45d58ef 133 Gene3D G3DSA:3.30.860.20 2 133 2.2E-53 T 23-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_04065 697943a60c37de8eb99c4dccb45d58ef 133 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 35 117 1.3E-26 T 23-10-2018 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 A3L08_04065 697943a60c37de8eb99c4dccb45d58ef 133 TIGRFAM TIGR01025 uS19_arch: ribosomal protein uS19 4 133 8.0E-66 T 23-10-2018 IPR005713 Ribosomal protein S19A/S15e GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_04065 697943a60c37de8eb99c4dccb45d58ef 133 SUPERFAMILY SSF54570 34 117 6.93E-31 T 23-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_04065 697943a60c37de8eb99c4dccb45d58ef 133 ProSitePatterns PS00323 Ribosomal protein S19 signature. 86 110 - T 23-10-2018 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_05135 d3f77106d8f23fc04d840456fc63827c 65 Gene3D G3DSA:2.20.25.100 11 65 6.4E-25 T 23-10-2018 IPR023407 Ribosomal protein S27e, zinc-binding domain superfamily A3L08_05135 d3f77106d8f23fc04d840456fc63827c 65 ProSitePatterns PS01168 Ribosomal protein S27e signature. 19 51 - T 23-10-2018 IPR000592 Ribosomal protein S27e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_05135 d3f77106d8f23fc04d840456fc63827c 65 Pfam PF01667 Ribosomal protein S27 11 64 2.3E-26 T 23-10-2018 IPR000592 Ribosomal protein S27e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_05135 d3f77106d8f23fc04d840456fc63827c 65 Hamap MF_00371 30S ribosomal protein S27e [rps27e]. 5 64 22.447 T 23-10-2018 IPR000592 Ribosomal protein S27e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_05135 d3f77106d8f23fc04d840456fc63827c 65 SUPERFAMILY SSF57829 11 65 3.66E-19 T 23-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 A3L08_09770 2cd12b36a18091972ca9336bdf60f1f0 421 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 6 138 3.9E-34 T 23-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 A3L08_09770 2cd12b36a18091972ca9336bdf60f1f0 421 TIGRFAM TIGR00936 ahcY: adenosylhomocysteinase 7 421 1.4E-209 T 23-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 A3L08_09770 2cd12b36a18091972ca9336bdf60f1f0 421 ProSitePatterns PS00738 S-adenosyl-L-homocysteine hydrolase signature 1. 78 92 - T 23-10-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 A3L08_09770 2cd12b36a18091972ca9336bdf60f1f0 421 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 142 416 5.5E-29 T 23-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 A3L08_09770 2cd12b36a18091972ca9336bdf60f1f0 421 Pfam PF00670 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 188 348 1.0E-50 T 23-10-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 A3L08_09770 2cd12b36a18091972ca9336bdf60f1f0 421 Gene3D G3DSA:3.40.50.720 190 349 6.1E-178 T 23-10-2018 A3L08_09770 2cd12b36a18091972ca9336bdf60f1f0 421 Gene3D G3DSA:3.40.50.1480 9 410 6.1E-178 T 23-10-2018 A3L08_09770 2cd12b36a18091972ca9336bdf60f1f0 421 SUPERFAMILY SSF52283 5 421 5.55E-103 T 23-10-2018 A3L08_09770 2cd12b36a18091972ca9336bdf60f1f0 421 Hamap MF_00563 Adenosylhomocysteinase [ahcY]. 2 421 50.649 T 23-10-2018 IPR034373 Adenosylhomocysteinase GO:0004013|GO:0019510|GO:0051287 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-2408508|Reactome: R-HSA-5578997 A3L08_09770 2cd12b36a18091972ca9336bdf60f1f0 421 SMART SM00997 188 349 7.1E-108 T 23-10-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 A3L08_09770 2cd12b36a18091972ca9336bdf60f1f0 421 PIRSF PIRSF001109 1 421 2.7E-197 T 23-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 A3L08_09770 2cd12b36a18091972ca9336bdf60f1f0 421 SMART SM00996 6 420 3.9E-142 T 23-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 A3L08_09770 2cd12b36a18091972ca9336bdf60f1f0 421 SUPERFAMILY SSF51735 188 350 5.71E-68 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L08_09770 2cd12b36a18091972ca9336bdf60f1f0 421 ProSitePatterns PS00739 S-adenosyl-L-homocysteine hydrolase signature 2. 210 226 - T 23-10-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 A3L08_02605 706685038521c3f13ae3312e7d4bfd1d 462 SUPERFAMILY SSF52540 79 355 2.41E-89 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_02605 706685038521c3f13ae3312e7d4bfd1d 462 Hamap MF_00310 V-type ATP synthase beta chain [atpB]. 3 459 62.49 T 23-10-2018 IPR022879 V-type ATP synthase regulatory subunit B/beta Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A3L08_02605 706685038521c3f13ae3312e7d4bfd1d 462 TIGRFAM TIGR01041 ATP_syn_B_arch: ATP synthase archaeal, B subunit 5 460 1.5E-266 T 23-10-2018 IPR005724 ATPase, A1 complex, beta subunit GO:0015986|GO:0033178|GO:0046933 A3L08_02605 706685038521c3f13ae3312e7d4bfd1d 462 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 9 75 6.4E-14 T 23-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A3L08_02605 706685038521c3f13ae3312e7d4bfd1d 462 Gene3D G3DSA:3.40.50.12240 2 459 3.5E-196 T 23-10-2018 A3L08_02605 706685038521c3f13ae3312e7d4bfd1d 462 PIRSF PIRSF039114 1 462 7.7E-256 T 23-10-2018 IPR022879 V-type ATP synthase regulatory subunit B/beta Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A3L08_02605 706685038521c3f13ae3312e7d4bfd1d 462 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 341 350 - T 23-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A3L08_02605 706685038521c3f13ae3312e7d4bfd1d 462 SUPERFAMILY SSF50615 5 67 6.28E-5 T 23-10-2018 IPR036121 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A3L08_02605 706685038521c3f13ae3312e7d4bfd1d 462 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 132 350 1.4E-69 T 23-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A3L08_02605 706685038521c3f13ae3312e7d4bfd1d 462 SUPERFAMILY SSF47917 362 420 2.01E-9 T 23-10-2018 A3L08_08995 375cc6f19a94556e91049ad50f61e77a 670 SUPERFAMILY SSF56300 129 397 4.32E-28 T 23-10-2018 A3L08_08995 375cc6f19a94556e91049ad50f61e77a 670 TIGRFAM TIGR04288 CGP_CTERM: CGP-CTERM domain 650 669 1.6E-7 T 23-10-2018 IPR027552 CGP-CTERM domain A3L08_08995 375cc6f19a94556e91049ad50f61e77a 670 Gene3D G3DSA:3.60.21.10 177 422 1.4E-17 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like A3L08_08995 375cc6f19a94556e91049ad50f61e77a 670 Pfam PF00149 Calcineurin-like phosphoesterase 129 371 1.2E-10 T 23-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 A3L08_07705 ef1ff79fe637ba89cf7979254b39dddd 166 Pfam PF00565 Staphylococcal nuclease homologue 85 161 7.6E-10 T 23-10-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold Reactome: R-HSA-6802952 A3L08_07705 ef1ff79fe637ba89cf7979254b39dddd 166 SMART SM00318 59 165 0.001 T 23-10-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold Reactome: R-HSA-6802952 A3L08_07705 ef1ff79fe637ba89cf7979254b39dddd 166 Gene3D G3DSA:2.40.50.90 53 165 7.0E-25 T 23-10-2018 IPR035437 SNase-like, OB-fold superfamily A3L08_07705 ef1ff79fe637ba89cf7979254b39dddd 166 SUPERFAMILY SSF50199 57 163 3.92E-19 T 23-10-2018 A3L08_08205 ef6390dd8d9e07b0570d736e64e8ac37 400 Gene3D G3DSA:3.40.50.2000 192 380 6.5E-116 T 23-10-2018 A3L08_08205 ef6390dd8d9e07b0570d736e64e8ac37 400 Gene3D G3DSA:3.40.50.2000 5 397 6.5E-116 T 23-10-2018 A3L08_08205 ef6390dd8d9e07b0570d736e64e8ac37 400 Pfam PF00534 Glycosyl transferases group 1 204 378 5.9E-40 T 23-10-2018 IPR001296 Glycosyl transferase, family 1 A3L08_08205 ef6390dd8d9e07b0570d736e64e8ac37 400 Pfam PF13439 Glycosyltransferase Family 4 22 195 2.1E-32 T 23-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 A3L08_08205 ef6390dd8d9e07b0570d736e64e8ac37 400 SUPERFAMILY SSF53756 1 400 9.42E-95 T 23-10-2018 A3L08_07375 525ece194439bb48d40942ac84681516 732 Pfam PF00009 Elongation factor Tu GTP binding domain 20 257 1.8E-64 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L08_07375 525ece194439bb48d40942ac84681516 732 Gene3D G3DSA:3.40.50.300 7 222 9.4E-74 T 23-10-2018 A3L08_07375 525ece194439bb48d40942ac84681516 732 SUPERFAMILY SSF52540 10 261 1.25E-69 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_07375 525ece194439bb48d40942ac84681516 732 SUPERFAMILY SSF54211 463 623 1.49E-48 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A3L08_07375 525ece194439bb48d40942ac84681516 732 Gene3D G3DSA:3.30.70.870 388 465 3.6E-27 T 23-10-2018 A3L08_07375 525ece194439bb48d40942ac84681516 732 SUPERFAMILY SSF50447 259 375 1.73E-33 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily A3L08_07375 525ece194439bb48d40942ac84681516 732 Pfam PF00679 Elongation factor G C-terminus 621 707 2.1E-24 T 23-10-2018 IPR000640 Elongation factor EFG, domain V-like A3L08_07375 525ece194439bb48d40942ac84681516 732 SUPERFAMILY SSF54980 624 718 2.88E-24 T 23-10-2018 IPR035647 EF-G domain III/V-like A3L08_07375 525ece194439bb48d40942ac84681516 732 Pfam PF03144 Elongation factor Tu domain 2 306 372 9.0E-15 T 23-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 A3L08_07375 525ece194439bb48d40942ac84681516 732 Gene3D G3DSA:2.40.30.10 259 386 4.5E-28 T 23-10-2018 A3L08_07375 525ece194439bb48d40942ac84681516 732 Gene3D G3DSA:3.30.230.10 472 720 1.6E-76 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A3L08_07375 525ece194439bb48d40942ac84681516 732 PRINTS PR00315 GTP-binding elongation factor signature 143 152 6.6E-16 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L08_07375 525ece194439bb48d40942ac84681516 732 PRINTS PR00315 GTP-binding elongation factor signature 67 75 6.6E-16 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L08_07375 525ece194439bb48d40942ac84681516 732 PRINTS PR00315 GTP-binding elongation factor signature 107 118 6.6E-16 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L08_07375 525ece194439bb48d40942ac84681516 732 PRINTS PR00315 GTP-binding elongation factor signature 23 36 6.6E-16 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L08_07375 525ece194439bb48d40942ac84681516 732 PRINTS PR00315 GTP-binding elongation factor signature 91 101 6.6E-16 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L08_07375 525ece194439bb48d40942ac84681516 732 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 21 153 2.9E-20 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A3L08_07375 525ece194439bb48d40942ac84681516 732 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 60 75 - T 23-10-2018 IPR031157 Tr-type G domain, conserved site A3L08_07375 525ece194439bb48d40942ac84681516 732 TIGRFAM TIGR00490 aEF-2: translation elongation factor aEF-2 3 720 0.0 T 23-10-2018 IPR004543 Translation elongation factor EFG/EF2, archaeal GO:0003746|GO:0005525|GO:0005737|GO:0006414 A3L08_07375 525ece194439bb48d40942ac84681516 732 Hamap MF_00054_A Elongation factor G [fusA]. 2 725 43.87 T 23-10-2018 IPR004543 Translation elongation factor EFG/EF2, archaeal GO:0003746|GO:0005525|GO:0005737|GO:0006414 A3L08_07375 525ece194439bb48d40942ac84681516 732 SMART SM00838 621 708 1.0E-45 T 23-10-2018 IPR000640 Elongation factor EFG, domain V-like A3L08_07375 525ece194439bb48d40942ac84681516 732 SUPERFAMILY SSF54980 388 463 3.2E-22 T 23-10-2018 IPR035647 EF-G domain III/V-like A3L08_07375 525ece194439bb48d40942ac84681516 732 Pfam PF03764 Elongation factor G, domain IV 513 619 6.9E-27 T 23-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 A3L08_07375 525ece194439bb48d40942ac84681516 732 Gene3D G3DSA:3.30.70.240 466 718 1.6E-76 T 23-10-2018 A3L08_07375 525ece194439bb48d40942ac84681516 732 Pfam PF14492 Elongation Factor G, domain II 387 459 3.8E-26 T 23-10-2018 A3L08_07375 525ece194439bb48d40942ac84681516 732 SMART SM00889 505 619 4.4E-19 T 23-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 A3L08_00415 e3218873ed1b323377c25cc7ecc2f630 157 Hamap MF_01404 Pyruvoyl-dependent arginine decarboxylase [pdaD]. 1 157 46.114 T 23-10-2018 IPR002724 Pyruvoyl-dependent arginine decarboxylase GO:0006527|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 A3L08_00415 e3218873ed1b323377c25cc7ecc2f630 157 Gene3D G3DSA:3.50.20.10 44 156 1.5E-33 T 23-10-2018 IPR016105 Pyruvoyl-dependent histidine/arginine decarboxylase, 3-layer sandwich domain GO:0006520|GO:0016831 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 A3L08_00415 e3218873ed1b323377c25cc7ecc2f630 157 ProDom PD010449 DECARBOXYLASE PYRUVOYL-DEPENDENT ARGININE SUBUNIT ALPHA CONTAINS: BETA PVLARGDC LYA DECARBOX 6 141 2.0E-70 T 23-10-2018 IPR002724 Pyruvoyl-dependent arginine decarboxylase GO:0006527|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 A3L08_00415 e3218873ed1b323377c25cc7ecc2f630 157 Gene3D G3DSA:3.30.60.30 1 43 3.5E-18 T 23-10-2018 A3L08_00415 e3218873ed1b323377c25cc7ecc2f630 157 Pfam PF01862 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) 5 154 2.9E-40 T 23-10-2018 IPR002724 Pyruvoyl-dependent arginine decarboxylase GO:0006527|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 A3L08_00415 e3218873ed1b323377c25cc7ecc2f630 157 PIRSF PIRSF005216 2 157 1.6E-46 T 23-10-2018 IPR002724 Pyruvoyl-dependent arginine decarboxylase GO:0006527|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 A3L08_00415 e3218873ed1b323377c25cc7ecc2f630 157 SUPERFAMILY SSF56271 2 155 7.32E-46 T 23-10-2018 IPR016104 Pyruvoyl-dependent histidine/arginine decarboxylase GO:0006520|GO:0016831 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 A3L08_00415 e3218873ed1b323377c25cc7ecc2f630 157 TIGRFAM TIGR00286 TIGR00286: arginine decarboxylase, pyruvoyl-dependent 6 153 8.7E-38 T 23-10-2018 IPR002724 Pyruvoyl-dependent arginine decarboxylase GO:0006527|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 A3L08_02145 f781d568c5ef0f72c3be84e51312da85 365 SUPERFAMILY SSF143437 100 181 2.96E-9 T 23-10-2018 A3L08_02145 f781d568c5ef0f72c3be84e51312da85 365 SUPERFAMILY SSF53335 179 359 2.16E-35 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L08_02145 f781d568c5ef0f72c3be84e51312da85 365 Gene3D G3DSA:3.40.50.150 190 365 3.3E-51 T 23-10-2018 A3L08_02145 f781d568c5ef0f72c3be84e51312da85 365 Pfam PF02926 THUMP domain 18 182 2.3E-27 T 23-10-2018 IPR004114 THUMP domain GO:0003723 A3L08_02145 f781d568c5ef0f72c3be84e51312da85 365 Gene3D G3DSA:3.30.2130.30 1 189 9.0E-83 T 23-10-2018 A3L08_02145 f781d568c5ef0f72c3be84e51312da85 365 Pfam PF01170 Putative RNA methylase family UPF0020 191 358 1.5E-37 T 23-10-2018 IPR000241 Putative RNA methylase domain A3L08_02145 f781d568c5ef0f72c3be84e51312da85 365 ProSitePatterns PS01261 Uncharacterized protein family UPF0020 signature. 223 234 - T 23-10-2018 IPR000241 Putative RNA methylase domain A3L08_02145 f781d568c5ef0f72c3be84e51312da85 365 SMART SM00981 86 182 6.1E-14 T 23-10-2018 IPR004114 THUMP domain GO:0003723 A3L08_09005 d7f7ce3cd52868c8fdd52fa98e868a27 715 Pfam PF04471 Restriction endonuclease 19 124 8.9E-14 T 23-10-2018 IPR007560 Restriction endonuclease type IV, Mrr GO:0003677|GO:0004519|GO:0009307 A3L08_09005 d7f7ce3cd52868c8fdd52fa98e868a27 715 SUPERFAMILY SSF52980 20 130 1.5E-7 T 23-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 A3L08_00160 52f26276decb4dcefbedac732d4ebcd8 152 Hamap MF_02115 FAD synthase [ribL]. 11 151 30.024 T 23-10-2018 IPR024902 FAD synthase RibL GO:0003919|GO:0006747|GO:0046444 KEGG: 00740+2.7.7.2|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A3L08_00160 52f26276decb4dcefbedac732d4ebcd8 152 SUPERFAMILY SSF52374 11 146 9.7E-27 T 23-10-2018 A3L08_00160 52f26276decb4dcefbedac732d4ebcd8 152 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 12 78 1.6E-19 T 23-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 A3L08_00160 52f26276decb4dcefbedac732d4ebcd8 152 Pfam PF01467 Cytidylyltransferase-like 14 145 6.0E-22 T 23-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 A3L08_00160 52f26276decb4dcefbedac732d4ebcd8 152 Gene3D G3DSA:3.40.50.620 1 152 1.3E-40 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L08_00960 394a169508fe4973d62fdbe8a21236e6 308 Pfam PF06463 Molybdenum Cofactor Synthesis C 180 307 8.2E-21 T 23-10-2018 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A3L08_00960 394a169508fe4973d62fdbe8a21236e6 308 Pfam PF13353 4Fe-4S single cluster domain 18 105 7.9E-12 T 23-10-2018 A3L08_00960 394a169508fe4973d62fdbe8a21236e6 308 Hamap MF_01225_A GTP 3',8-cyclase [moaA]. 3 308 42.601 T 23-10-2018 IPR013485 Molybdenum cofactor biosynthesis protein A, archaea GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823 A3L08_00960 394a169508fe4973d62fdbe8a21236e6 308 Pfam PF04055 Radical SAM superfamily 17 172 1.2E-34 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L08_00960 394a169508fe4973d62fdbe8a21236e6 308 Gene3D G3DSA:3.20.20.70 1 306 7.2E-78 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L08_00960 394a169508fe4973d62fdbe8a21236e6 308 SMART SM00729 12 213 4.5E-15 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A3L08_00960 394a169508fe4973d62fdbe8a21236e6 308 SUPERFAMILY SSF102114 4 297 2.35E-69 T 23-10-2018 A3L08_00960 394a169508fe4973d62fdbe8a21236e6 308 TIGRFAM TIGR02668 moaA_archaeal: probable molybdenum cofactor biosynthesis protein A 3 308 1.1E-125 T 23-10-2018 IPR013485 Molybdenum cofactor biosynthesis protein A, archaea GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823 A3L08_00960 394a169508fe4973d62fdbe8a21236e6 308 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 18 29 - T 23-10-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A3L08_06065 c30c6b2cd05b13785e4644a85db59233 253 Pfam PF04055 Radical SAM superfamily 31 187 5.6E-14 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L08_06065 c30c6b2cd05b13785e4644a85db59233 253 SUPERFAMILY SSF102114 32 209 1.44E-12 T 23-10-2018 A3L08_06065 c30c6b2cd05b13785e4644a85db59233 253 Pfam PF13353 4Fe-4S single cluster domain 29 147 2.8E-8 T 23-10-2018 A3L08_06065 c30c6b2cd05b13785e4644a85db59233 253 Hamap MF_00917 7-carboxy-7-deazaguanine synthase [queE]. 3 253 39.752 T 23-10-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 A3L08_06065 c30c6b2cd05b13785e4644a85db59233 253 Gene3D G3DSA:3.20.20.70 4 253 4.2E-27 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L08_06065 c30c6b2cd05b13785e4644a85db59233 253 PIRSF PIRSF000370 2 253 2.4E-32 T 23-10-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 A3L08_05140 84c746aa95f471e1b151153e5f899af0 275 SUPERFAMILY SSF50249 7 87 2.86E-21 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L08_05140 84c746aa95f471e1b151153e5f899af0 275 Gene3D G3DSA:2.40.50.140 3 85 2.2E-32 T 23-10-2018 A3L08_05140 84c746aa95f471e1b151153e5f899af0 275 SUPERFAMILY SSF110993 176 260 8.89E-22 T 23-10-2018 IPR024055 Translation initiation factor 2, alpha subunit, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-381042|Reactome: R-HSA-382556|Reactome: R-HSA-72649|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72731 A3L08_05140 84c746aa95f471e1b151153e5f899af0 275 Hamap MF_00231 Translation initiation factor 2 subunit alpha [eif2a]. 3 263 34.099 T 23-10-2018 IPR022964 Translation initiation factor 2, alpha subunit, archaeal A3L08_05140 84c746aa95f471e1b151153e5f899af0 275 SMART SM00316 10 83 2.1E-24 T 23-10-2018 IPR022967 RNA-binding domain, S1 A3L08_05140 84c746aa95f471e1b151153e5f899af0 275 Gene3D G3DSA:3.30.70.1130 173 262 1.4E-32 T 23-10-2018 IPR024055 Translation initiation factor 2, alpha subunit, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-381042|Reactome: R-HSA-382556|Reactome: R-HSA-72649|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72731 A3L08_05140 84c746aa95f471e1b151153e5f899af0 275 Pfam PF07541 Eukaryotic translation initiation factor 2 alpha subunit 122 233 7.2E-23 T 23-10-2018 IPR011488 Translation initiation factor 2, alpha subunit GO:0003723|GO:0003743 Reactome: R-HSA-156827|Reactome: R-HSA-381042|Reactome: R-HSA-382556|Reactome: R-HSA-72649|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72731 A3L08_05140 84c746aa95f471e1b151153e5f899af0 275 Gene3D G3DSA:1.10.150.190 86 171 3.7E-33 T 23-10-2018 IPR024054 Translation initiation factor 2, alpha subunit, middle domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-381042|Reactome: R-HSA-382556|Reactome: R-HSA-72649|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72731 A3L08_05140 84c746aa95f471e1b151153e5f899af0 275 SUPERFAMILY SSF116742 85 174 4.05E-24 T 23-10-2018 IPR024054 Translation initiation factor 2, alpha subunit, middle domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-381042|Reactome: R-HSA-382556|Reactome: R-HSA-72649|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72731 A3L08_05140 84c746aa95f471e1b151153e5f899af0 275 Pfam PF00575 S1 RNA binding domain 9 83 7.7E-15 T 23-10-2018 IPR003029 S1 domain GO:0003676 A3L08_01890 0babd597fe918ce717c4928cf0d7e93d 278 Gene3D G3DSA:3.20.20.70 5 245 3.8E-16 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L08_01890 0babd597fe918ce717c4928cf0d7e93d 278 SUPERFAMILY SSF102114 16 231 3.92E-28 T 23-10-2018 A3L08_01890 0babd597fe918ce717c4928cf0d7e93d 278 Pfam PF04055 Radical SAM superfamily 21 162 7.9E-8 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L08_01890 0babd597fe918ce717c4928cf0d7e93d 278 SMART SM00729 16 219 3.0E-4 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A3L08_08585 4214033730d0d06e3314f696688991e8 180 Pfam PF03266 NTPase 4 167 7.6E-56 T 23-10-2018 IPR004948 Nucleoside-triphosphatase, THEP1 type GO:0098519 KEGG: 00230+3.6.1.15|KEGG: 00730+3.6.1.15|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210 A3L08_08585 4214033730d0d06e3314f696688991e8 180 SMART SM00382 1 158 6.4E-6 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L08_08585 4214033730d0d06e3314f696688991e8 180 SUPERFAMILY SSF52540 5 169 1.19E-21 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_08585 4214033730d0d06e3314f696688991e8 180 Gene3D G3DSA:3.40.50.300 3 175 2.4E-42 T 23-10-2018 A3L08_08585 4214033730d0d06e3314f696688991e8 180 Hamap MF_00796 Nucleoside-triphosphatase . 3 175 30.084 T 23-10-2018 IPR004948 Nucleoside-triphosphatase, THEP1 type GO:0098519 KEGG: 00230+3.6.1.15|KEGG: 00730+3.6.1.15|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210 A3L08_00685 b732fcf1030e1c5900bbc05e0c8aaefb 481 Gene3D G3DSA:3.10.20.440 4 100 1.1E-32 T 23-10-2018 A3L08_00685 b732fcf1030e1c5900bbc05e0c8aaefb 481 Gene3D G3DSA:3.50.50.60 237 367 2.4E-59 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L08_00685 b732fcf1030e1c5900bbc05e0c8aaefb 481 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 269 287 7.9E-27 T 23-10-2018 A3L08_00685 b732fcf1030e1c5900bbc05e0c8aaefb 481 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 391 413 7.9E-27 T 23-10-2018 A3L08_00685 b732fcf1030e1c5900bbc05e0c8aaefb 481 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 119 138 7.9E-27 T 23-10-2018 A3L08_00685 b732fcf1030e1c5900bbc05e0c8aaefb 481 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 359 375 7.9E-27 T 23-10-2018 A3L08_00685 b732fcf1030e1c5900bbc05e0c8aaefb 481 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 225 243 7.9E-27 T 23-10-2018 A3L08_00685 b732fcf1030e1c5900bbc05e0c8aaefb 481 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 118 425 2.3E-38 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A3L08_00685 b732fcf1030e1c5900bbc05e0c8aaefb 481 Gene3D G3DSA:3.50.50.60 118 442 2.4E-59 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L08_00685 b732fcf1030e1c5900bbc05e0c8aaefb 481 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 15 95 1.1E-26 T 23-10-2018 A3L08_00685 b732fcf1030e1c5900bbc05e0c8aaefb 481 SUPERFAMILY SSF51905 107 433 5.59E-42 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L08_00685 b732fcf1030e1c5900bbc05e0c8aaefb 481 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 60 68 - T 23-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 A3L08_00685 b732fcf1030e1c5900bbc05e0c8aaefb 481 SUPERFAMILY SSF54292 17 99 7.42E-21 T 23-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 A3L08_00685 b732fcf1030e1c5900bbc05e0c8aaefb 481 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 228 237 2.0E-22 T 23-10-2018 A3L08_00685 b732fcf1030e1c5900bbc05e0c8aaefb 481 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 269 294 2.0E-22 T 23-10-2018 A3L08_00685 b732fcf1030e1c5900bbc05e0c8aaefb 481 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 118 140 2.0E-22 T 23-10-2018 A3L08_00685 b732fcf1030e1c5900bbc05e0c8aaefb 481 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 360 374 2.0E-22 T 23-10-2018 A3L08_00685 b732fcf1030e1c5900bbc05e0c8aaefb 481 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 406 413 2.0E-22 T 23-10-2018 A3L08_06910 83a8e351be7a2ae9942e1bc419eafc97 321 Pfam PF06973 Domain of unknown function (DUF1297) 157 310 3.9E-43 T 23-10-2018 IPR009720 IMP biosynthesis enzyme PurP, C-terminal GO:0000287|GO:0005524|GO:0006188|GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 A3L08_06910 83a8e351be7a2ae9942e1bc419eafc97 321 SUPERFAMILY SSF56059 99 310 6.45E-68 T 23-10-2018 A3L08_06910 83a8e351be7a2ae9942e1bc419eafc97 321 Gene3D G3DSA:3.30.1490.20 112 165 2.6E-77 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 A3L08_06910 83a8e351be7a2ae9942e1bc419eafc97 321 Gene3D G3DSA:3.30.470.20 85 308 2.6E-77 T 23-10-2018 A3L08_06910 83a8e351be7a2ae9942e1bc419eafc97 321 Gene3D G3DSA:3.40.50.20 1 83 1.3E-29 T 23-10-2018 A3L08_06910 83a8e351be7a2ae9942e1bc419eafc97 321 Pfam PF06849 Protein of unknown function (DUF1246) 3 113 8.4E-34 T 23-10-2018 IPR010672 IMP biosynthesis enzyme PurP, N-terminal GO:0000287|GO:0005524|GO:0006188|GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 A3L08_06910 83a8e351be7a2ae9942e1bc419eafc97 321 SUPERFAMILY SSF52440 3 95 7.1E-31 T 23-10-2018 IPR016185 Pre-ATP-grasp domain superfamily A3L08_03790 74815bf0007ea6ab1c5a10bf96da5fe8 132 Pfam PF09999 Uncharacterized protein conserved in archaea (DUF2240) 9 127 2.6E-10 T 23-10-2018 IPR018716 Protein of unknown function DUF2240 A3L08_08975 cebc29eb2008fbfa70721097b298d5dc 480 Pfam PF13416 Bacterial extracellular solute-binding protein 87 326 1.0E-17 T 23-10-2018 IPR006059 Bacterial extracellular solute-binding protein A3L08_08975 cebc29eb2008fbfa70721097b298d5dc 480 Gene3D G3DSA:3.40.190.10 85 312 1.3E-32 T 23-10-2018 A3L08_08975 cebc29eb2008fbfa70721097b298d5dc 480 Gene3D G3DSA:3.40.190.10 150 269 1.3E-32 T 23-10-2018 A3L08_08975 cebc29eb2008fbfa70721097b298d5dc 480 SUPERFAMILY SSF53850 68 325 1.61E-38 T 23-10-2018 A3L08_01080 9da2f37cf21e5252accb96b8f23d4e59 309 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 5 307 39.686 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A3L08_01080 9da2f37cf21e5252accb96b8f23d4e59 309 Gene3D G3DSA:3.40.50.1370 135 292 2.5E-124 T 23-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 A3L08_01080 9da2f37cf21e5252accb96b8f23d4e59 309 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 51 70 1.1E-23 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A3L08_01080 9da2f37cf21e5252accb96b8f23d4e59 309 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 270 293 1.1E-23 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A3L08_01080 9da2f37cf21e5252accb96b8f23d4e59 309 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 260 269 1.1E-23 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A3L08_01080 9da2f37cf21e5252accb96b8f23d4e59 309 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 135 146 1.1E-23 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A3L08_01080 9da2f37cf21e5252accb96b8f23d4e59 309 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 6 304 2.7E-133 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A3L08_01080 9da2f37cf21e5252accb96b8f23d4e59 309 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 154 302 5.6E-30 T 23-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 A3L08_01080 9da2f37cf21e5252accb96b8f23d4e59 309 SUPERFAMILY SSF53671 2 306 1.02E-102 T 23-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 A3L08_01080 9da2f37cf21e5252accb96b8f23d4e59 309 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 6 147 1.0E-49 T 23-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 A3L08_01080 9da2f37cf21e5252accb96b8f23d4e59 309 Gene3D G3DSA:3.40.50.1370 7 301 2.5E-124 T 23-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 A3L08_01080 9da2f37cf21e5252accb96b8f23d4e59 309 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 51 58 - T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A3L08_01080 9da2f37cf21e5252accb96b8f23d4e59 309 PRINTS PR00101 Aspartate carbamoyltransferase signature 286 300 2.6E-38 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A3L08_01080 9da2f37cf21e5252accb96b8f23d4e59 309 PRINTS PR00101 Aspartate carbamoyltransferase signature 225 234 2.6E-38 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A3L08_01080 9da2f37cf21e5252accb96b8f23d4e59 309 PRINTS PR00101 Aspartate carbamoyltransferase signature 80 89 2.6E-38 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A3L08_01080 9da2f37cf21e5252accb96b8f23d4e59 309 PRINTS PR00101 Aspartate carbamoyltransferase signature 134 151 2.6E-38 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A3L08_01080 9da2f37cf21e5252accb96b8f23d4e59 309 PRINTS PR00101 Aspartate carbamoyltransferase signature 41 63 2.6E-38 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A3L08_01080 9da2f37cf21e5252accb96b8f23d4e59 309 PRINTS PR00101 Aspartate carbamoyltransferase signature 264 269 2.6E-38 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A3L08_01220 57383451cab0a71c1dd4c205fa66449d 368 Pfam PF01546 Peptidase family M20/M25/M40 61 365 2.9E-28 T 23-10-2018 IPR002933 Peptidase M20 GO:0016787 A3L08_01220 57383451cab0a71c1dd4c205fa66449d 368 Gene3D G3DSA:3.30.70.360 167 278 2.1E-77 T 23-10-2018 A3L08_01220 57383451cab0a71c1dd4c205fa66449d 368 SUPERFAMILY SSF55031 166 265 8.37E-14 T 23-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain A3L08_01220 57383451cab0a71c1dd4c205fa66449d 368 SUPERFAMILY SSF53187 4 367 4.29E-56 T 23-10-2018 A3L08_01220 57383451cab0a71c1dd4c205fa66449d 368 Pfam PF07687 Peptidase dimerisation domain 164 267 6.6E-14 T 23-10-2018 IPR011650 Peptidase M20, dimerisation domain A3L08_01220 57383451cab0a71c1dd4c205fa66449d 368 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 93 131 - T 23-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 A3L08_01220 57383451cab0a71c1dd4c205fa66449d 368 Gene3D G3DSA:3.40.630.10 5 356 2.1E-77 T 23-10-2018 A3L08_08850 b1149a71651fbfcd4c6bd87bed110d16 431 Pfam PF00152 tRNA synthetases class II (D, K and N) 110 425 3.0E-86 T 23-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L08_08850 b1149a71651fbfcd4c6bd87bed110d16 431 Gene3D G3DSA:2.40.50.140 1 101 5.2E-30 T 23-10-2018 A3L08_08850 b1149a71651fbfcd4c6bd87bed110d16 431 SUPERFAMILY SSF50249 4 99 1.22E-25 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L08_08850 b1149a71651fbfcd4c6bd87bed110d16 431 PRINTS PR01042 Aspartyl-tRNA synthetase signature 197 210 9.8E-15 T 23-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L08_08850 b1149a71651fbfcd4c6bd87bed110d16 431 PRINTS PR01042 Aspartyl-tRNA synthetase signature 386 400 9.8E-15 T 23-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L08_08850 b1149a71651fbfcd4c6bd87bed110d16 431 PRINTS PR01042 Aspartyl-tRNA synthetase signature 346 362 9.8E-15 T 23-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L08_08850 b1149a71651fbfcd4c6bd87bed110d16 431 PRINTS PR01042 Aspartyl-tRNA synthetase signature 181 193 9.8E-15 T 23-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L08_08850 b1149a71651fbfcd4c6bd87bed110d16 431 Pfam PF01336 OB-fold nucleic acid binding domain 19 97 3.5E-15 T 23-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 A3L08_08850 b1149a71651fbfcd4c6bd87bed110d16 431 Gene3D G3DSA:3.30.930.10 105 431 2.7E-116 T 23-10-2018 A3L08_08850 b1149a71651fbfcd4c6bd87bed110d16 431 TIGRFAM TIGR00457 asnS: asparagine--tRNA ligase 14 430 1.5E-129 T 23-10-2018 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22 A3L08_08850 b1149a71651fbfcd4c6bd87bed110d16 431 SUPERFAMILY SSF55681 110 426 3.03E-87 T 23-10-2018 A3L08_08840 96dfdf4e2da49cedbc5a3021d8aa35c1 141 Gene3D G3DSA:2.40.50.140 69 141 4.3E-17 T 23-10-2018 A3L08_08840 96dfdf4e2da49cedbc5a3021d8aa35c1 141 SUPERFAMILY SSF141322 75 141 1.27E-14 T 23-10-2018 A3L08_08840 96dfdf4e2da49cedbc5a3021d8aa35c1 141 Pfam PF01957 NfeD-like C-terminal, partner-binding 8 140 7.9E-13 T 23-10-2018 IPR002810 NfeD-like, C-terminal domain A3L08_01800 d35e24cfc3ff2d77f8ab7ec6f98de361 141 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 77 88 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L08_01800 d35e24cfc3ff2d77f8ab7ec6f98de361 141 SUPERFAMILY SSF54862 27 106 2.23E-21 T 23-10-2018 A3L08_01800 d35e24cfc3ff2d77f8ab7ec6f98de361 141 Gene3D G3DSA:3.30.70.3270 23 141 4.8E-21 T 23-10-2018 A3L08_01800 d35e24cfc3ff2d77f8ab7ec6f98de361 141 Pfam PF13187 4Fe-4S dicluster domain 45 91 1.0E-10 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L08_01800 d35e24cfc3ff2d77f8ab7ec6f98de361 141 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 46 57 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L08_08395 bea0d90eeab4fd78242c9bafafa688b3 212 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 170 208 1.5E-9 T 23-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 A3L08_08395 bea0d90eeab4fd78242c9bafafa688b3 212 Gene3D G3DSA:3.30.980.10 85 212 4.3E-43 T 23-10-2018 A3L08_08395 bea0d90eeab4fd78242c9bafafa688b3 212 SMART SM00863 165 208 3.3E-9 T 23-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 A3L08_08395 bea0d90eeab4fd78242c9bafafa688b3 212 SUPERFAMILY SSF50447 2 84 1.98E-21 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily A3L08_08395 bea0d90eeab4fd78242c9bafafa688b3 212 SUPERFAMILY SSF55186 85 210 2.22E-33 T 23-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 A3L08_08395 bea0d90eeab4fd78242c9bafafa688b3 212 Pfam PF01411 tRNA synthetases class II (A) 13 87 5.1E-13 T 23-10-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 A3L08_08395 bea0d90eeab4fd78242c9bafafa688b3 212 Gene3D G3DSA:2.40.30.130 13 84 3.3E-32 T 23-10-2018 A3L08_01170 4737942752d6f19a2819b9afe6c09801 425 Gene3D G3DSA:3.30.2290.10 1 204 1.1E-18 T 23-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal A3L08_01170 4737942752d6f19a2819b9afe6c09801 425 Pfam PF01523 Putative modulator of DNA gyrase 15 300 2.3E-46 T 23-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 A3L08_01170 4737942752d6f19a2819b9afe6c09801 425 SUPERFAMILY SSF111283 2 420 2.09E-85 T 23-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 A3L08_01580 e212e1bbde70fdba93db5ceecb29525b 83 Pfam PF03685 Uncharacterised protein family (UPF0147) 3 82 5.0E-33 T 23-10-2018 IPR005354 Uncharacterised protein family UPF0147 A3L08_01580 e212e1bbde70fdba93db5ceecb29525b 83 ProDom PD029943 UPF0147 ARCHAEAL PF0239 ST0460.1 MM1385 CYTOSOLIC SACI_0891 TV0625 APES069 TA0600 1 83 1.0E-38 T 23-10-2018 IPR005354 Uncharacterised protein family UPF0147 A3L08_01580 e212e1bbde70fdba93db5ceecb29525b 83 Hamap MF_00342 UPF0147 protein . 1 83 29.529 T 23-10-2018 IPR005354 Uncharacterised protein family UPF0147 A3L08_01580 e212e1bbde70fdba93db5ceecb29525b 83 Gene3D G3DSA:1.20.1440.50 2 83 5.5E-31 T 23-10-2018 IPR023130 Ta0600-like superfamily A3L08_01580 e212e1bbde70fdba93db5ceecb29525b 83 SUPERFAMILY SSF158436 3 83 9.81E-30 T 23-10-2018 A3L08_00045 2268e3c6a2282713b0a3eb911d49fe8f 266 SUPERFAMILY SSF102114 30 219 1.31E-7 T 23-10-2018 A3L08_00045 2268e3c6a2282713b0a3eb911d49fe8f 266 Pfam PF04055 Radical SAM superfamily 29 183 1.2E-9 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L08_01990 ec5454158eaee14c74093470106ad171 181 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 8 61 3.8E-12 T 23-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 A3L08_01990 ec5454158eaee14c74093470106ad171 181 Pfam PF01467 Cytidylyltransferase-like 9 145 5.3E-14 T 23-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 A3L08_01990 ec5454158eaee14c74093470106ad171 181 Gene3D G3DSA:3.40.50.620 6 154 3.9E-41 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L08_01990 ec5454158eaee14c74093470106ad171 181 SUPERFAMILY SSF52374 3 147 7.6E-20 T 23-10-2018 A3L08_06145 865c276b0abd7a1432298d219ef6412d 153 Gene3D G3DSA:1.10.10.10 4 58 7.2E-22 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L08_06145 865c276b0abd7a1432298d219ef6412d 153 SUPERFAMILY SSF46785 7 76 4.42E-16 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L08_06145 865c276b0abd7a1432298d219ef6412d 153 Gene3D G3DSA:3.30.70.920 59 147 1.1E-20 T 23-10-2018 A3L08_06145 865c276b0abd7a1432298d219ef6412d 153 SMART SM00344 7 113 1.1E-42 T 23-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A3L08_06145 865c276b0abd7a1432298d219ef6412d 153 Pfam PF13404 AsnC-type helix-turn-helix domain 7 47 2.2E-16 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L08_06145 865c276b0abd7a1432298d219ef6412d 153 Pfam PF01037 Lrp/AsnC ligand binding domain 73 142 1.9E-14 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A3L08_06145 865c276b0abd7a1432298d219ef6412d 153 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 23 34 6.3E-13 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L08_06145 865c276b0abd7a1432298d219ef6412d 153 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 7 23 6.3E-13 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L08_06145 865c276b0abd7a1432298d219ef6412d 153 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 34 53 6.3E-13 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L08_06145 865c276b0abd7a1432298d219ef6412d 153 SUPERFAMILY SSF54909 67 144 1.11E-16 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel A3L08_03650 8c51b9631c0dea7fd0841a9b5020ffea 146 SUPERFAMILY SSF46785 4 63 1.77E-15 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L08_03650 8c51b9631c0dea7fd0841a9b5020ffea 146 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 64 129 3.0E-20 T 23-10-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 A3L08_03650 8c51b9631c0dea7fd0841a9b5020ffea 146 Gene3D G3DSA:1.10.60.10 69 124 1.0E-19 T 23-10-2018 IPR036421 Iron dependent repressor, metal binding and dimerisation domain superfamily GO:0046914|GO:0046983 A3L08_03650 8c51b9631c0dea7fd0841a9b5020ffea 146 SUPERFAMILY SSF47979 64 124 2.88E-17 T 23-10-2018 IPR036421 Iron dependent repressor, metal binding and dimerisation domain superfamily GO:0046914|GO:0046983 A3L08_03650 8c51b9631c0dea7fd0841a9b5020ffea 146 Gene3D G3DSA:1.10.10.10 3 68 4.6E-25 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L08_03650 8c51b9631c0dea7fd0841a9b5020ffea 146 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 3 58 3.8E-17 T 23-10-2018 IPR022687 DTXR-type HTH domain GO:0003677 A3L08_03650 8c51b9631c0dea7fd0841a9b5020ffea 146 SMART SM00529 25 124 2.9E-43 T 23-10-2018 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 A3L08_06445 e3de2846e3a867e2dac46735f6cb9c08 246 SUPERFAMILY SSF52540 2 226 4.65E-47 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_06445 e3de2846e3a867e2dac46735f6cb9c08 246 Pfam PF00005 ABC transporter 17 167 2.1E-22 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L08_06445 e3de2846e3a867e2dac46735f6cb9c08 246 TIGRFAM TIGR01978 sufC: FeS assembly ATPase SufC 2 239 6.7E-84 T 23-10-2018 IPR010230 FeS cluster assembly SUF system, ATPase SufC GO:0005524 A3L08_06445 e3de2846e3a867e2dac46735f6cb9c08 246 Gene3D G3DSA:3.40.50.300 1 243 4.1E-56 T 23-10-2018 A3L08_06445 e3de2846e3a867e2dac46735f6cb9c08 246 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L08_06445 e3de2846e3a867e2dac46735f6cb9c08 246 SMART SM00382 26 219 4.3E-9 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L08_08460 6756efe24aeae667ce51d6238e6f3c64 339 Pfam PF00709 Adenylosuccinate synthetase 149 289 1.6E-44 T 23-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 A3L08_08460 6756efe24aeae667ce51d6238e6f3c64 339 Pfam PF00709 Adenylosuccinate synthetase 5 148 6.4E-38 T 23-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 A3L08_08460 6756efe24aeae667ce51d6238e6f3c64 339 Pfam PF00709 Adenylosuccinate synthetase 294 333 6.1E-6 T 23-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 A3L08_08460 6756efe24aeae667ce51d6238e6f3c64 339 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 10 17 - T 23-10-2018 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 A3L08_08460 6756efe24aeae667ce51d6238e6f3c64 339 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 339 99.286 T 23-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 A3L08_08460 6756efe24aeae667ce51d6238e6f3c64 339 SUPERFAMILY SSF52540 1 335 1.59E-108 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_08460 6756efe24aeae667ce51d6238e6f3c64 339 Gene3D G3DSA:3.40.440.10 1 339 1.1E-138 T 23-10-2018 A3L08_08460 6756efe24aeae667ce51d6238e6f3c64 339 SMART SM00788 3 334 1.6E-160 T 23-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 A3L08_03165 fdfd6042bae64480e61b7f84d6c6efc6 545 Gene3D G3DSA:3.30.260.10 147 405 4.9E-212 T 23-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily A3L08_03165 fdfd6042bae64480e61b7f84d6c6efc6 545 Gene3D G3DSA:3.50.7.10 218 369 4.9E-212 T 23-10-2018 IPR027409 GroEL-like apical domain superfamily A3L08_03165 fdfd6042bae64480e61b7f84d6c6efc6 545 Gene3D G3DSA:1.10.560.10 28 522 4.9E-212 T 23-10-2018 IPR027413 GroEL-like equatorial domain superfamily A3L08_03165 fdfd6042bae64480e61b7f84d6c6efc6 545 SUPERFAMILY SSF52029 212 378 3.35E-63 T 23-10-2018 IPR027409 GroEL-like apical domain superfamily A3L08_03165 fdfd6042bae64480e61b7f84d6c6efc6 545 SUPERFAMILY SSF54849 146 404 4.88E-29 T 23-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily A3L08_03165 fdfd6042bae64480e61b7f84d6c6efc6 545 ProSitePatterns PS00750 Chaperonins TCP-1 signature 1. 40 52 - T 23-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 A3L08_03165 fdfd6042bae64480e61b7f84d6c6efc6 545 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 89 108 2.8E-34 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 A3L08_03165 fdfd6042bae64480e61b7f84d6c6efc6 545 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 373 395 2.8E-34 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 A3L08_03165 fdfd6042bae64480e61b7f84d6c6efc6 545 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 37 53 2.8E-34 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 A3L08_03165 fdfd6042bae64480e61b7f84d6c6efc6 545 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 407 419 2.8E-34 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 A3L08_03165 fdfd6042bae64480e61b7f84d6c6efc6 545 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 59 77 2.8E-34 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 A3L08_03165 fdfd6042bae64480e61b7f84d6c6efc6 545 ProSitePatterns PS00995 Chaperonins TCP-1 signature 3. 89 97 - T 23-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 A3L08_03165 fdfd6042bae64480e61b7f84d6c6efc6 545 SUPERFAMILY SSF48592 17 524 3.46E-93 T 23-10-2018 IPR027413 GroEL-like equatorial domain superfamily A3L08_03165 fdfd6042bae64480e61b7f84d6c6efc6 545 Pfam PF00118 TCP-1/cpn60 chaperonin family 35 525 2.2E-183 T 23-10-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 A3L08_03165 fdfd6042bae64480e61b7f84d6c6efc6 545 TIGRFAM TIGR02339 thermosome_arch: thermosome, various subunits, archaeal 8 524 4.2E-243 T 23-10-2018 IPR012714 Thermosome, archaeal GO:0005524|GO:0006457|GO:0051082 A3L08_03165 fdfd6042bae64480e61b7f84d6c6efc6 545 ProSitePatterns PS00751 Chaperonins TCP-1 signature 2. 61 77 - T 23-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 A3L08_09015 b1bc72a11722f75290a0e9f24f4bf75f 255 TIGRFAM TIGR01247 drrB: daunorubicin resistance ABC transporter membrane protein 10 249 2.9E-106 T 23-10-2018 IPR005942 Daunorubicin resistance ABC transporter membrane protein A3L08_09015 b1bc72a11722f75290a0e9f24f4bf75f 255 PIRSF PIRSF006648 1 254 8.3E-66 T 23-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A3L08_09015 b1bc72a11722f75290a0e9f24f4bf75f 255 Pfam PF01061 ABC-2 type transporter 4 215 7.9E-41 T 23-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 A3L08_09015 b1bc72a11722f75290a0e9f24f4bf75f 255 PRINTS PR00164 ABC-2 type transport system membrane protein signature 175 194 1.1E-16 T 23-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A3L08_09015 b1bc72a11722f75290a0e9f24f4bf75f 255 PRINTS PR00164 ABC-2 type transport system membrane protein signature 22 43 1.1E-16 T 23-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A3L08_09015 b1bc72a11722f75290a0e9f24f4bf75f 255 PRINTS PR00164 ABC-2 type transport system membrane protein signature 195 214 1.1E-16 T 23-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A3L08_09015 b1bc72a11722f75290a0e9f24f4bf75f 255 PRINTS PR00164 ABC-2 type transport system membrane protein signature 138 162 1.1E-16 T 23-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A3L08_09015 b1bc72a11722f75290a0e9f24f4bf75f 255 PRINTS PR00164 ABC-2 type transport system membrane protein signature 101 126 1.1E-16 T 23-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A3L08_00820 b0ba1da97b06d8c69a1c2c3a0d50d438 440 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 37 177 2.3E-6 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L08_00820 b0ba1da97b06d8c69a1c2c3a0d50d438 440 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 3 14 4.2E-7 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L08_00820 b0ba1da97b06d8c69a1c2c3a0d50d438 440 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 172 185 4.2E-7 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L08_00820 b0ba1da97b06d8c69a1c2c3a0d50d438 440 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 145 165 4.2E-7 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L08_00820 b0ba1da97b06d8c69a1c2c3a0d50d438 440 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 94 107 4.2E-7 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L08_00820 b0ba1da97b06d8c69a1c2c3a0d50d438 440 Gene3D G3DSA:3.90.550.10 214 436 3.1E-46 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L08_00820 b0ba1da97b06d8c69a1c2c3a0d50d438 440 SUPERFAMILY SSF56784 1 217 2.94E-37 T 23-10-2018 IPR036412 HAD-like superfamily A3L08_00820 b0ba1da97b06d8c69a1c2c3a0d50d438 440 SUPERFAMILY SSF53448 219 423 4.1E-32 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L08_00820 b0ba1da97b06d8c69a1c2c3a0d50d438 440 Pfam PF00535 Glycosyl transferase family 2 221 343 4.6E-23 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A3L08_00820 b0ba1da97b06d8c69a1c2c3a0d50d438 440 Gene3D G3DSA:3.40.50.1000 6 184 9.6E-31 T 23-10-2018 IPR023214 HAD superfamily A3L08_00820 b0ba1da97b06d8c69a1c2c3a0d50d438 440 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 182 3.8E-23 T 23-10-2018 A3L08_00820 b0ba1da97b06d8c69a1c2c3a0d50d438 440 Gene3D G3DSA:1.10.150.240 18 80 9.6E-31 T 23-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 A3L08_00745 9f40d91d65dd2c0c8ee007836653cf0d 299 SUPERFAMILY SSF56281 1 248 5.11E-18 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L08_00745 9f40d91d65dd2c0c8ee007836653cf0d 299 Hamap MF_01406 UPF0282 protein . 1 286 39.169 T 23-10-2018 IPR014426 Uncharacterised protein family UPF0282, hydrolase, metallo-beta-lactamase A3L08_00745 9f40d91d65dd2c0c8ee007836653cf0d 299 Pfam PF12706 Beta-lactamase superfamily domain 27 206 1.6E-8 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L08_00745 9f40d91d65dd2c0c8ee007836653cf0d 299 PIRSF PIRSF004944 1 299 2.7E-115 T 23-10-2018 IPR014426 Uncharacterised protein family UPF0282, hydrolase, metallo-beta-lactamase A3L08_00745 9f40d91d65dd2c0c8ee007836653cf0d 299 SMART SM00849 14 244 0.0084 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L08_00745 9f40d91d65dd2c0c8ee007836653cf0d 299 Gene3D G3DSA:3.60.15.10 8 267 4.5E-17 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L08_03005 3d00a9d5504f60f833f4bab2a23d3261 271 Pfam PF09721 Transmembrane exosortase (Exosortase_EpsH) 29 255 1.9E-17 T 23-10-2018 IPR019127 Exosortase A3L08_03005 3d00a9d5504f60f833f4bab2a23d3261 271 TIGRFAM TIGR04178 exo_archaeo: exosortase/archaeosortase family protein 166 258 6.6E-16 T 23-10-2018 IPR026392 Exosortase/Archaeosortase domain A3L08_02050 a92aa935ca48820a2d74562eefd4349d 242 Gene3D G3DSA:3.40.50.10900 1 242 9.4E-73 T 23-10-2018 IPR038389 Proteasome assembly chaperone 2 superfamily A3L08_02050 a92aa935ca48820a2d74562eefd4349d 242 TIGRFAM TIGR00161 TIGR00161: TIGR00161 family protein 2 234 3.5E-66 T 23-10-2018 IPR004425 Conserved hypothetical protein CHP00061 A3L08_02050 a92aa935ca48820a2d74562eefd4349d 242 Pfam PF09754 PAC2 family 19 222 2.5E-45 T 23-10-2018 IPR019151 Proteasome assembly chaperone 2 A3L08_02050 a92aa935ca48820a2d74562eefd4349d 242 SUPERFAMILY SSF159659 11 237 2.22E-48 T 23-10-2018 A3L08_08220 d05c0c611de9dd755bb674ca36c58a1d 372 Pfam PF00005 ABC transporter 20 167 2.5E-31 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L08_08220 d05c0c611de9dd755bb674ca36c58a1d 372 Gene3D G3DSA:3.40.50.300 1 243 1.7E-77 T 23-10-2018 A3L08_08220 d05c0c611de9dd755bb674ca36c58a1d 372 Pfam PF08402 TOBE domain 288 363 4.9E-5 T 23-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 A3L08_08220 d05c0c611de9dd755bb674ca36c58a1d 372 SUPERFAMILY SSF52540 4 248 9.94E-91 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_08220 d05c0c611de9dd755bb674ca36c58a1d 372 Gene3D G3DSA:2.40.50.140 310 354 3.4E-21 T 23-10-2018 A3L08_08220 d05c0c611de9dd755bb674ca36c58a1d 372 SUPERFAMILY SSF50331 242 371 6.07E-24 T 23-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal A3L08_08220 d05c0c611de9dd755bb674ca36c58a1d 372 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L08_08220 d05c0c611de9dd755bb674ca36c58a1d 372 Gene3D G3DSA:2.40.50.100 245 304 2.0E-22 T 23-10-2018 A3L08_08220 d05c0c611de9dd755bb674ca36c58a1d 372 SMART SM00382 28 217 7.9E-14 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L08_00190 acca67cf775f2ef097df3f06d023734b 392 Pfam PF00155 Aminotransferase class I and II 34 384 2.5E-77 T 23-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A3L08_00190 acca67cf775f2ef097df3f06d023734b 392 Gene3D G3DSA:3.90.1150.10 34 384 4.3E-134 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A3L08_00190 acca67cf775f2ef097df3f06d023734b 392 Gene3D G3DSA:3.40.640.10 65 284 4.3E-134 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A3L08_00190 acca67cf775f2ef097df3f06d023734b 392 SUPERFAMILY SSF53383 10 391 3.36E-123 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A3L08_00190 acca67cf775f2ef097df3f06d023734b 392 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 234 247 - T 23-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 A3L08_04150 530d4ce8d63bcf3959b35c8e61cdc7ac 229 Pfam PF00333 Ribosomal protein S5, N-terminal domain 56 117 3.4E-21 T 23-10-2018 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 A3L08_04150 530d4ce8d63bcf3959b35c8e61cdc7ac 229 Gene3D G3DSA:3.30.160.770 6 116 2.9E-37 T 23-10-2018 A3L08_04150 530d4ce8d63bcf3959b35c8e61cdc7ac 229 SUPERFAMILY SSF54768 56 119 3.56E-18 T 23-10-2018 A3L08_04150 530d4ce8d63bcf3959b35c8e61cdc7ac 229 ProSitePatterns PS00585 Ribosomal protein S5 signature. 71 103 - T 23-10-2018 IPR018192 Ribosomal protein S5, N-terminal, conserved site A3L08_04150 530d4ce8d63bcf3959b35c8e61cdc7ac 229 SUPERFAMILY SSF54211 132 204 2.07E-19 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A3L08_04150 530d4ce8d63bcf3959b35c8e61cdc7ac 229 Pfam PF03719 Ribosomal protein S5, C-terminal domain 139 205 1.5E-21 T 23-10-2018 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 A3L08_04150 530d4ce8d63bcf3959b35c8e61cdc7ac 229 Hamap MF_01307_A 30S ribosomal protein S5 [rpsE]. 2 206 47.767 T 23-10-2018 IPR005711 Ribosomal protein S5, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-3214858|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8876725|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_04150 530d4ce8d63bcf3959b35c8e61cdc7ac 229 Gene3D G3DSA:3.30.230.10 117 209 8.4E-30 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A3L08_04150 530d4ce8d63bcf3959b35c8e61cdc7ac 229 TIGRFAM TIGR01020 uS5_euk_arch: ribosomal protein uS5 4 215 1.4E-105 T 23-10-2018 IPR005711 Ribosomal protein S5, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-3214858|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8876725|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_01510 60cff6a9729a7150079ccd335ee36465 559 SUPERFAMILY SSF117018 2 242 3.92E-71 T 23-10-2018 IPR036599 DNA ligase, ATP-dependent, N-terminal domain superfamily GO:0003677|GO:0003910|GO:0006281|GO:0006310 A3L08_01510 60cff6a9729a7150079ccd335ee36465 559 SUPERFAMILY SSF50249 425 552 3.2E-40 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L08_01510 60cff6a9729a7150079ccd335ee36465 559 Gene3D G3DSA:2.40.50.140 423 559 2.0E-52 T 23-10-2018 A3L08_01510 60cff6a9729a7150079ccd335ee36465 559 Gene3D G3DSA:1.10.3260.10 1 220 9.8E-86 T 23-10-2018 IPR036599 DNA ligase, ATP-dependent, N-terminal domain superfamily GO:0003677|GO:0003910|GO:0006281|GO:0006310 A3L08_01510 60cff6a9729a7150079ccd335ee36465 559 ProSitePatterns PS00697 ATP-dependent DNA ligase AMP-binding site. 247 255 - T 23-10-2018 IPR016059 DNA ligase, ATP-dependent, conserved site GO:0003909|GO:0051103 A3L08_01510 60cff6a9729a7150079ccd335ee36465 559 Pfam PF04679 ATP dependent DNA ligase C terminal region 443 534 1.9E-20 T 23-10-2018 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 A3L08_01510 60cff6a9729a7150079ccd335ee36465 559 Pfam PF04675 DNA ligase N terminus 3 176 3.5E-39 T 23-10-2018 IPR012308 DNA ligase, ATP-dependent, N-terminal GO:0003677|GO:0003910|GO:0006281|GO:0006310 A3L08_01510 60cff6a9729a7150079ccd335ee36465 559 SUPERFAMILY SSF56091 219 422 2.37E-54 T 23-10-2018 A3L08_01510 60cff6a9729a7150079ccd335ee36465 559 Hamap MF_00407 DNA ligase [lig]. 1 550 34.682 T 23-10-2018 IPR022865 DNA ligase, ATP-dependent, bacterial/archaeal GO:0003910 A3L08_01510 60cff6a9729a7150079ccd335ee36465 559 Pfam PF01068 ATP dependent DNA ligase domain 224 422 4.4E-65 T 23-10-2018 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 A3L08_01510 60cff6a9729a7150079ccd335ee36465 559 Gene3D G3DSA:3.30.470.30 221 422 7.7E-74 T 23-10-2018 A3L08_01510 60cff6a9729a7150079ccd335ee36465 559 TIGRFAM TIGR00574 dnl1: DNA ligase I, ATP-dependent (dnl1) 57 550 2.0E-162 T 23-10-2018 IPR000977 DNA ligase, ATP-dependent GO:0003910|GO:0005524|GO:0006281|GO:0006310|GO:0071897 A3L08_01510 60cff6a9729a7150079ccd335ee36465 559 ProSitePatterns PS00333 ATP-dependent DNA ligase signature 2. 398 422 - T 23-10-2018 IPR016059 DNA ligase, ATP-dependent, conserved site GO:0003909|GO:0051103 A3L08_01410 17748d5ff5e10ea5e35f46ef4cbec084 398 Pfam PF01571 Aminomethyltransferase folate-binding domain 8 287 4.6E-98 T 23-10-2018 IPR006222 Aminomethyltransferase, folate-binding domain A3L08_01410 17748d5ff5e10ea5e35f46ef4cbec084 398 PIRSF PIRSF006487 1 398 1.6E-105 T 23-10-2018 IPR028896 Aminomethyltransferase-like KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 A3L08_01410 17748d5ff5e10ea5e35f46ef4cbec084 398 Gene3D G3DSA:3.30.1360.120 8 255 1.2E-90 T 23-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 A3L08_01410 17748d5ff5e10ea5e35f46ef4cbec084 398 Gene3D G3DSA:4.10.1250.10 269 305 1.4E-8 T 23-10-2018 A3L08_01410 17748d5ff5e10ea5e35f46ef4cbec084 398 TIGRFAM TIGR00528 gcvT: glycine cleavage system T protein 3 387 2.1E-93 T 23-10-2018 IPR006223 Glycine cleavage system T protein GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 A3L08_01410 17748d5ff5e10ea5e35f46ef4cbec084 398 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 293 383 5.4E-25 T 23-10-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 A3L08_01410 17748d5ff5e10ea5e35f46ef4cbec084 398 Gene3D G3DSA:3.30.70.1400 52 143 1.2E-90 T 23-10-2018 A3L08_01410 17748d5ff5e10ea5e35f46ef4cbec084 398 Hamap MF_00259 Aminomethyltransferase [gcvT]. 1 389 43.317 T 23-10-2018 IPR022903 Glycine cleavage system T protein, bacteria GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 A3L08_01410 17748d5ff5e10ea5e35f46ef4cbec084 398 Gene3D G3DSA:2.40.30.110 310 383 4.8E-31 T 23-10-2018 A3L08_01410 17748d5ff5e10ea5e35f46ef4cbec084 398 SUPERFAMILY SSF103025 2 308 1.08E-94 T 23-10-2018 A3L08_01410 17748d5ff5e10ea5e35f46ef4cbec084 398 SUPERFAMILY SSF101790 311 392 7.19E-25 T 23-10-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal A3L08_00290 2050aa1654869066657eb6addb230ba2 392 Gene3D G3DSA:1.10.3720.10 131 370 1.0E-28 T 23-10-2018 IPR035906 MetI-like superfamily A3L08_00290 2050aa1654869066657eb6addb230ba2 392 SUPERFAMILY SSF161098 137 356 2.88E-30 T 23-10-2018 IPR035906 MetI-like superfamily A3L08_00290 2050aa1654869066657eb6addb230ba2 392 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 160 375 1.5E-32 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A3L08_04885 fb8dc20a3ec235467df1a1301304ddd3 624 ProSitePatterns PS00505 Phosphoenolpyruvate carboxykinase (GTP) signature. 268 276 - T 23-10-2018 IPR018091 Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site GO:0004613 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 A3L08_04885 fb8dc20a3ec235467df1a1301304ddd3 624 SUPERFAMILY SSF53795 244 605 2.98E-109 T 23-10-2018 A3L08_04885 fb8dc20a3ec235467df1a1301304ddd3 624 Gene3D G3DSA:2.170.8.10 65 398 4.4E-148 T 23-10-2018 A3L08_04885 fb8dc20a3ec235467df1a1301304ddd3 624 Pfam PF17297 Phosphoenolpyruvate carboxykinase N-terminal domain 30 239 2.1E-58 T 23-10-2018 IPR035078 Phosphoenolpyruvate carboxykinase, GTP-utilising, N-terminal GO:0004611|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 A3L08_04885 fb8dc20a3ec235467df1a1301304ddd3 624 Hamap MF_00452 Phosphoenolpyruvate carboxykinase [GTP] [pckG]. 18 606 36.691 T 23-10-2018 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 A3L08_04885 fb8dc20a3ec235467df1a1301304ddd3 624 Pfam PF00821 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain 244 605 8.2E-107 T 23-10-2018 IPR035077 Phosphoenolpyruvate carboxykinase, GTP-utilising, C-terminal GO:0004611|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 A3L08_04885 fb8dc20a3ec235467df1a1301304ddd3 624 Gene3D G3DSA:3.40.449.10 27 246 4.4E-148 T 23-10-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 A3L08_04885 fb8dc20a3ec235467df1a1301304ddd3 624 SUPERFAMILY SSF68923 11 243 1.41E-63 T 23-10-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 A3L08_04885 fb8dc20a3ec235467df1a1301304ddd3 624 Gene3D G3DSA:3.90.228.20 247 604 4.4E-148 T 23-10-2018 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 A3L08_04885 fb8dc20a3ec235467df1a1301304ddd3 624 PIRSF PIRSF001348 5 609 7.1E-211 T 23-10-2018 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 A3L08_06665 ea7050b4439b8176f76d310275c42e57 405 Gene3D G3DSA:3.30.300.340 18 286 1.0E-171 T 23-10-2018 A3L08_06665 ea7050b4439b8176f76d310275c42e57 405 Hamap MF_00136 S-adenosylmethionine synthase [mat]. 5 405 52.01 T 23-10-2018 IPR002795 S-adenosylmethionine synthetase, archaea GO:0004478|GO:0005524|GO:0006730 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912 A3L08_06665 ea7050b4439b8176f76d310275c42e57 405 ProDom PD011777 SYNTHETASE TRANSFERASE METHIONINE ADENOSYLTRANSFERASE S-ADENOSYLMETHIONINE NUCLEOTIDE-BINDING METABOLISM ATP-BINDING MAGNESIUM ONE-CARBON 21 405 0.0 T 23-10-2018 A3L08_06665 ea7050b4439b8176f76d310275c42e57 405 Gene3D G3DSA:3.30.300.10 30 154 1.0E-171 T 23-10-2018 A3L08_06665 ea7050b4439b8176f76d310275c42e57 405 Gene3D G3DSA:3.30.300.280 16 398 1.0E-171 T 23-10-2018 A3L08_06665 ea7050b4439b8176f76d310275c42e57 405 Pfam PF01941 S-adenosylmethionine synthetase (AdoMet synthetase) 6 401 4.4E-180 T 23-10-2018 IPR027790 S-adenosylmethionine synthase KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912 A3L08_02415 88fe29bfa42c9ec605ececed0ceeea0c 304 Gene3D G3DSA:3.40.50.620 1 303 1.5E-88 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L08_02415 88fe29bfa42c9ec605ececed0ceeea0c 304 PIRSF PIRSF004976 1 303 5.8E-94 T 23-10-2018 IPR035107 tRNA thiolation protein, TtcA/Ctu1 type GO:0008033 Reactome: R-HSA-6782315 A3L08_02415 88fe29bfa42c9ec605ececed0ceeea0c 304 TIGRFAM TIGR00269 TIGR00269: TIGR00269 family protein 192 291 3.0E-25 T 23-10-2018 IPR000541 Cytoplasmic tRNA 2-thiolation protein 1 GO:0000049|GO:0002098|GO:0034227 Reactome: R-HSA-6782315 A3L08_02415 88fe29bfa42c9ec605ececed0ceeea0c 304 SUPERFAMILY SSF52402 24 245 1.12E-49 T 23-10-2018 A3L08_02415 88fe29bfa42c9ec605ececed0ceeea0c 304 Pfam PF01171 PP-loop family 49 221 1.7E-13 T 23-10-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 A3L08_01160 8df96b6d25f17d4cd75c68c425d7362e 710 Pfam PF16657 Maltogenic Amylase, C-terminal domain 409 482 1.2E-8 T 23-10-2018 IPR032091 Maltogenic Amylase, C-terminal A3L08_01160 8df96b6d25f17d4cd75c68c425d7362e 710 Pfam PF00128 Alpha amylase, catalytic domain 48 367 2.7E-57 T 23-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 A3L08_01160 8df96b6d25f17d4cd75c68c425d7362e 710 SUPERFAMILY SSF81296 491 565 1.54E-12 T 23-10-2018 IPR014756 Immunoglobulin E-set A3L08_01160 8df96b6d25f17d4cd75c68c425d7362e 710 SUPERFAMILY SSF51011 409 485 3.06E-15 T 23-10-2018 A3L08_01160 8df96b6d25f17d4cd75c68c425d7362e 710 Gene3D G3DSA:3.20.20.80 9 402 1.6E-106 T 23-10-2018 A3L08_01160 8df96b6d25f17d4cd75c68c425d7362e 710 Gene3D G3DSA:2.60.40.1180 403 487 1.2E-13 T 23-10-2018 IPR013780 Glycosyl hydrolase, all-beta A3L08_01160 8df96b6d25f17d4cd75c68c425d7362e 710 SMART SM00642 17 400 4.6E-83 T 23-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 A3L08_01160 8df96b6d25f17d4cd75c68c425d7362e 710 Pfam PF01833 IPT/TIG domain 492 570 1.9E-9 T 23-10-2018 IPR002909 IPT domain A3L08_01160 8df96b6d25f17d4cd75c68c425d7362e 710 Gene3D G3DSA:2.60.40.10 491 568 4.1E-14 T 23-10-2018 IPR013783 Immunoglobulin-like fold A3L08_01160 8df96b6d25f17d4cd75c68c425d7362e 710 SMART SM00632 412 488 9.3E-4 T 23-10-2018 IPR031319 Alpha-amylase, C-terminal domain Reactome: R-HSA-189085 A3L08_01160 8df96b6d25f17d4cd75c68c425d7362e 710 SUPERFAMILY SSF51445 9 406 3.43E-83 T 23-10-2018 IPR017853 Glycoside hydrolase superfamily A3L08_09545 fd40e953db9e115aa7aef887ec6577a5 132 Gene3D G3DSA:3.40.140.10 3 132 1.0E-31 T 23-10-2018 A3L08_09545 fd40e953db9e115aa7aef887ec6577a5 132 SMART SM00232 2 129 2.8E-16 T 23-10-2018 IPR000555 JAB1/MPN/MOV34 metalloenzyme domain GO:0005515 A3L08_09545 fd40e953db9e115aa7aef887ec6577a5 132 SUPERFAMILY SSF102712 2 126 5.75E-26 T 23-10-2018 A3L08_09545 fd40e953db9e115aa7aef887ec6577a5 132 Pfam PF14464 Prokaryotic homologs of the JAB domain 17 109 1.6E-18 T 23-10-2018 IPR028090 JAB domain, prokaryotic A3L08_09685 5c6ac2ce967ceca14a6082003849bd45 146 Gene3D G3DSA:1.10.10.10 54 136 3.8E-7 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L08_09685 5c6ac2ce967ceca14a6082003849bd45 146 SUPERFAMILY SSF46785 59 133 7.87E-8 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L08_08040 78878fef3b0a2e468bba8c7bebf340d7 746 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 377 383 - T 23-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 A3L08_08040 78878fef3b0a2e468bba8c7bebf340d7 746 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 185 199 2.7E-11 T 23-10-2018 A3L08_08040 78878fef3b0a2e468bba8c7bebf340d7 746 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 153 169 2.7E-11 T 23-10-2018 A3L08_08040 78878fef3b0a2e468bba8c7bebf340d7 746 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 374 386 2.7E-11 T 23-10-2018 A3L08_08040 78878fef3b0a2e468bba8c7bebf340d7 746 SUPERFAMILY SSF53335 60 703 1.52E-49 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L08_08040 78878fef3b0a2e468bba8c7bebf340d7 746 Pfam PF02384 N-6 DNA Methylase 581 662 3.7E-6 T 23-10-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 A3L08_08040 78878fef3b0a2e468bba8c7bebf340d7 746 Pfam PF02384 N-6 DNA Methylase 131 256 3.0E-13 T 23-10-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 A3L08_08040 78878fef3b0a2e468bba8c7bebf340d7 746 Gene3D G3DSA:3.40.50.150 543 674 3.3E-15 T 23-10-2018 A3L08_02060 6541850a1d7c554c30e4be3d5dc248e0 424 Pfam PF01979 Amidohydrolase family 51 397 3.4E-78 T 23-10-2018 IPR006680 Amidohydrolase-related GO:0016787 A3L08_02060 6541850a1d7c554c30e4be3d5dc248e0 424 Hamap MF_01281 5'-deoxyadenosine deaminase [dadD]. 2 424 48.17 T 23-10-2018 IPR023512 Deaminase MtaD/DadD GO:0019239 A3L08_02060 6541850a1d7c554c30e4be3d5dc248e0 424 SUPERFAMILY SSF51338 1 423 6.2E-38 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A3L08_02060 6541850a1d7c554c30e4be3d5dc248e0 424 Gene3D G3DSA:3.20.20.140 55 344 5.6E-155 T 23-10-2018 A3L08_02060 6541850a1d7c554c30e4be3d5dc248e0 424 SUPERFAMILY SSF51556 54 347 7.99E-105 T 23-10-2018 IPR032466 Metal-dependent hydrolase A3L08_02060 6541850a1d7c554c30e4be3d5dc248e0 424 Gene3D G3DSA:2.30.40.10 4 416 5.6E-155 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A3L08_01975 30777bd0ad8a591e3fee408ac40ee3fb 325 ProSitePatterns PS01016 Glycoprotease family signature. 92 112 - T 23-10-2018 IPR017860 Peptidase M22, conserved site Reactome: R-HSA-6782315 A3L08_01975 30777bd0ad8a591e3fee408ac40ee3fb 325 TIGRFAM TIGR03722 arch_KAE1: universal archaeal protein Kae1 4 324 1.6E-152 T 23-10-2018 IPR022449 tRNA N6-adenosine threonylcarbamoyltransferase Kae1, archaea GO:0000408|GO:0002949 A3L08_01975 30777bd0ad8a591e3fee408ac40ee3fb 325 Gene3D G3DSA:3.30.420.40 4 299 5.2E-114 T 23-10-2018 A3L08_01975 30777bd0ad8a591e3fee408ac40ee3fb 325 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 124 136 1.4E-41 T 23-10-2018 IPR017861 Kae1/TsaD family A3L08_01975 30777bd0ad8a591e3fee408ac40ee3fb 325 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 93 112 1.4E-41 T 23-10-2018 IPR017861 Kae1/TsaD family A3L08_01975 30777bd0ad8a591e3fee408ac40ee3fb 325 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 146 167 1.4E-41 T 23-10-2018 IPR017861 Kae1/TsaD family A3L08_01975 30777bd0ad8a591e3fee408ac40ee3fb 325 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 4 17 1.4E-41 T 23-10-2018 IPR017861 Kae1/TsaD family A3L08_01975 30777bd0ad8a591e3fee408ac40ee3fb 325 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 72 92 1.4E-41 T 23-10-2018 IPR017861 Kae1/TsaD family A3L08_01975 30777bd0ad8a591e3fee408ac40ee3fb 325 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 248 257 1.4E-41 T 23-10-2018 IPR017861 Kae1/TsaD family A3L08_01975 30777bd0ad8a591e3fee408ac40ee3fb 325 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 4 291 9.4E-101 T 23-10-2018 IPR017861 Kae1/TsaD family A3L08_01975 30777bd0ad8a591e3fee408ac40ee3fb 325 Pfam PF00814 Glycoprotease family 23 292 3.1E-95 T 23-10-2018 IPR000905 Gcp-like domain A3L08_01975 30777bd0ad8a591e3fee408ac40ee3fb 325 Hamap MF_01446 tRNA N6-adenosine threonylcarbamoyltransferase [kae1]. 1 325 38.338 T 23-10-2018 IPR034680 tRNA N6-adenosine threonylcarbamoyltransferase Kae1/OSGEP GO:0000408|GO:0002949 Reactome: R-HSA-6782315 A3L08_01975 30777bd0ad8a591e3fee408ac40ee3fb 325 Gene3D G3DSA:3.30.420.40 122 278 5.2E-114 T 23-10-2018 A3L08_01975 30777bd0ad8a591e3fee408ac40ee3fb 325 SUPERFAMILY SSF53067 1 293 2.81E-38 T 23-10-2018 A3L08_03285 9eb7fcde3e93ea6a2f5c19e0d986493f 307 Pfam PF02540 NAD synthase 157 186 7.3E-5 T 23-10-2018 IPR022310 NAD/GMP synthase A3L08_03285 9eb7fcde3e93ea6a2f5c19e0d986493f 307 Pfam PF02540 NAD synthase 4 81 2.2E-6 T 23-10-2018 IPR022310 NAD/GMP synthase A3L08_03285 9eb7fcde3e93ea6a2f5c19e0d986493f 307 SUPERFAMILY SSF54810 189 307 1.24E-44 T 23-10-2018 A3L08_03285 9eb7fcde3e93ea6a2f5c19e0d986493f 307 Pfam PF00958 GMP synthase C terminal domain 218 306 6.8E-34 T 23-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 A3L08_03285 9eb7fcde3e93ea6a2f5c19e0d986493f 307 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 4 307 8.8E-152 T 23-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 A3L08_03285 9eb7fcde3e93ea6a2f5c19e0d986493f 307 SUPERFAMILY SSF52402 2 224 1.37E-54 T 23-10-2018 A3L08_03285 9eb7fcde3e93ea6a2f5c19e0d986493f 307 Gene3D G3DSA:3.40.50.620 2 189 1.6E-78 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L08_03285 9eb7fcde3e93ea6a2f5c19e0d986493f 307 Gene3D G3DSA:3.30.300.10 190 307 1.4E-52 T 23-10-2018 A3L08_03285 9eb7fcde3e93ea6a2f5c19e0d986493f 307 Hamap MF_00345 GMP synthase [glutamine-hydrolyzing] subunit B [guaAB]. 1 307 45.741 T 23-10-2018 IPR026598 GMP synthase subunit B KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 A3L08_09715 4e80181b77edf2d2fc5267337c7656a2 236 SUPERFAMILY SSF56784 1 231 5.74E-48 T 23-10-2018 IPR036412 HAD-like superfamily A3L08_09715 4e80181b77edf2d2fc5267337c7656a2 236 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 146 162 1.3E-9 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L08_09715 4e80181b77edf2d2fc5267337c7656a2 236 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 2 13 1.3E-9 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L08_09715 4e80181b77edf2d2fc5267337c7656a2 236 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 164 184 1.3E-9 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L08_09715 4e80181b77edf2d2fc5267337c7656a2 236 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 115 128 1.3E-9 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L08_09715 4e80181b77edf2d2fc5267337c7656a2 236 Gene3D G3DSA:1.10.150.240 16 101 1.9E-58 T 23-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 A3L08_09715 4e80181b77edf2d2fc5267337c7656a2 236 Gene3D G3DSA:3.40.50.1000 4 223 1.9E-58 T 23-10-2018 IPR023214 HAD superfamily A3L08_09715 4e80181b77edf2d2fc5267337c7656a2 236 TIGRFAM TIGR02253 CTE7: HAD hydrolase, TIGR02253 family 1 227 9.1E-55 T 23-10-2018 IPR011950 HAD-superfamily hydrolase, subfamily IA, CTE7 GO:0016787 Reactome: R-HSA-4085001 A3L08_09715 4e80181b77edf2d2fc5267337c7656a2 236 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 106 203 4.9E-8 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L08_09715 4e80181b77edf2d2fc5267337c7656a2 236 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 110 197 4.3E-11 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L08_09715 4e80181b77edf2d2fc5267337c7656a2 236 Pfam PF13419 Haloacid dehalogenase-like hydrolase 56 202 1.0E-26 T 23-10-2018 A3L08_09210 97b865324fb77fd6c0a472b600c40477 280 Gene3D G3DSA:3.30.1360.130 118 264 2.4E-75 T 23-10-2018 A3L08_09210 97b865324fb77fd6c0a472b600c40477 280 SUPERFAMILY SSF63992 1 275 2.75E-84 T 23-10-2018 IPR036177 Peptidase M55, D-aminopeptidase superfamily A3L08_09210 97b865324fb77fd6c0a472b600c40477 280 Pfam PF04951 D-aminopeptidase 1 265 6.0E-83 T 23-10-2018 IPR007035 Peptidase M55, D-aminopeptidase A3L08_09210 97b865324fb77fd6c0a472b600c40477 280 Gene3D G3DSA:3.40.50.10780 1 217 2.4E-75 T 23-10-2018 IPR027476 D-aminopeptidase, N-terminal A3L08_09210 97b865324fb77fd6c0a472b600c40477 280 PIRSF PIRSF015853 1 277 2.5E-98 T 23-10-2018 IPR007035 Peptidase M55, D-aminopeptidase A3L08_07990 1aa7162f5b1e7092836e740b84acd86b 372 Pfam PF01497 Periplasmic binding protein 52 293 1.1E-29 T 23-10-2018 IPR002491 ABC transporter periplasmic binding domain A3L08_07990 1aa7162f5b1e7092836e740b84acd86b 372 Gene3D G3DSA:3.40.50.1980 173 368 9.0E-86 T 23-10-2018 A3L08_07990 1aa7162f5b1e7092836e740b84acd86b 372 Gene3D G3DSA:3.40.50.1980 27 172 8.4E-59 T 23-10-2018 A3L08_07990 1aa7162f5b1e7092836e740b84acd86b 372 SUPERFAMILY SSF53807 36 349 1.57E-59 T 23-10-2018 A3L08_05725 4a118435c93bc013da631d5c58dd0128 122 SUPERFAMILY SSF47819 1 120 6.1E-24 T 23-10-2018 IPR010997 HRDC-like superfamily GO:0000166|GO:0003824|GO:0044237 A3L08_05725 4a118435c93bc013da631d5c58dd0128 122 Pfam PF03874 RNA polymerase Rpb4 11 119 3.9E-7 T 23-10-2018 IPR005574 RNA polymerase subunit RPB4/RPC9 GO:0006352|GO:0030880 A3L08_05725 4a118435c93bc013da631d5c58dd0128 122 Gene3D G3DSA:1.10.150.80 55 122 2.7E-29 T 23-10-2018 A3L08_05725 4a118435c93bc013da631d5c58dd0128 122 Gene3D G3DSA:1.10.287.420 1 54 1.5E-36 T 23-10-2018 A3L08_05725 4a118435c93bc013da631d5c58dd0128 122 PIRSF PIRSF005053 1 120 3.2E-29 T 23-10-2018 IPR010924 DNA-directed RNA polymerase subunit F (Rpo4) A3L08_04945 eb7426d47c4b01ec0eadeb7c3ce9435d 493 SUPERFAMILY SSF53067 249 487 3.61E-83 T 23-10-2018 A3L08_04945 eb7426d47c4b01ec0eadeb7c3ce9435d 493 PIRSF PIRSF000538 2 493 7.5E-179 T 23-10-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 A3L08_04945 eb7426d47c4b01ec0eadeb7c3ce9435d 493 Gene3D G3DSA:3.30.420.40 248 493 5.2E-94 T 23-10-2018 A3L08_04945 eb7426d47c4b01ec0eadeb7c3ce9435d 493 Gene3D G3DSA:3.30.420.40 1 247 7.6E-115 T 23-10-2018 A3L08_04945 eb7426d47c4b01ec0eadeb7c3ce9435d 493 Hamap MF_00186 Glycerol kinase [glpK]. 2 488 57.478 T 23-10-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 A3L08_04945 eb7426d47c4b01ec0eadeb7c3ce9435d 493 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 4 246 1.7E-87 T 23-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 A3L08_04945 eb7426d47c4b01ec0eadeb7c3ce9435d 493 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 355 375 - T 23-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 A3L08_04945 eb7426d47c4b01ec0eadeb7c3ce9435d 493 SUPERFAMILY SSF53067 4 248 2.83E-94 T 23-10-2018 A3L08_04945 eb7426d47c4b01ec0eadeb7c3ce9435d 493 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 132 144 - T 23-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 A3L08_04945 eb7426d47c4b01ec0eadeb7c3ce9435d 493 TIGRFAM TIGR01311 glycerol_kin: glycerol kinase 4 487 3.5E-215 T 23-10-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 A3L08_04945 eb7426d47c4b01ec0eadeb7c3ce9435d 493 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 256 441 3.0E-55 T 23-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 A3L08_04165 8045b1c108d9c9a26423ea1e0c4d2914 482 Hamap MF_01465 Protein translocase subunit SecY [secY]. 18 477 20.433 T 23-10-2018 IPR026593 Protein translocase subunit SecY A3L08_04165 8045b1c108d9c9a26423ea1e0c4d2914 482 PIRSF PIRSF004557 6 482 1.2E-101 T 23-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A3L08_04165 8045b1c108d9c9a26423ea1e0c4d2914 482 Gene3D G3DSA:1.10.3370.10 27 482 1.1E-177 T 23-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A3L08_04165 8045b1c108d9c9a26423ea1e0c4d2914 482 SUPERFAMILY SSF103491 8 468 5.23E-110 T 23-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A3L08_04165 8045b1c108d9c9a26423ea1e0c4d2914 482 PRINTS PR00303 Preprotein translocase SecY subunit signature 446 464 9.1E-7 T 23-10-2018 A3L08_04165 8045b1c108d9c9a26423ea1e0c4d2914 482 PRINTS PR00303 Preprotein translocase SecY subunit signature 160 185 9.1E-7 T 23-10-2018 A3L08_04165 8045b1c108d9c9a26423ea1e0c4d2914 482 PRINTS PR00303 Preprotein translocase SecY subunit signature 186 209 9.1E-7 T 23-10-2018 A3L08_04165 8045b1c108d9c9a26423ea1e0c4d2914 482 PRINTS PR00303 Preprotein translocase SecY subunit signature 31 49 9.1E-7 T 23-10-2018 A3L08_04165 8045b1c108d9c9a26423ea1e0c4d2914 482 ProSitePatterns PS00755 Protein secY signature 1. 73 92 - T 23-10-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A3L08_04165 8045b1c108d9c9a26423ea1e0c4d2914 482 ProSitePatterns PS00756 Protein secY signature 2. 179 196 - T 23-10-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A3L08_04165 8045b1c108d9c9a26423ea1e0c4d2914 482 Pfam PF10559 Plug domain of Sec61p 39 72 1.2E-10 T 23-10-2018 IPR019561 Translocon Sec61/SecY, plug domain Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A3L08_04165 8045b1c108d9c9a26423ea1e0c4d2914 482 Pfam PF00344 SecY translocase 73 461 2.5E-70 T 23-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A3L08_04165 8045b1c108d9c9a26423ea1e0c4d2914 482 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 28 470 2.5E-90 T 23-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A3L08_09410 60c6d631b7015e844c19e76169b653e5 455 Gene3D G3DSA:1.10.287.40 1 107 2.5E-34 T 23-10-2018 A3L08_09410 60c6d631b7015e844c19e76169b653e5 455 PRINTS PR00981 Seryl-tRNA synthetase signature 285 297 1.3E-32 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A3L08_09410 60c6d631b7015e844c19e76169b653e5 455 PRINTS PR00981 Seryl-tRNA synthetase signature 354 370 1.3E-32 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A3L08_09410 60c6d631b7015e844c19e76169b653e5 455 PRINTS PR00981 Seryl-tRNA synthetase signature 297 310 1.3E-32 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A3L08_09410 60c6d631b7015e844c19e76169b653e5 455 PRINTS PR00981 Seryl-tRNA synthetase signature 337 350 1.3E-32 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A3L08_09410 60c6d631b7015e844c19e76169b653e5 455 PRINTS PR00981 Seryl-tRNA synthetase signature 372 388 1.3E-32 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A3L08_09410 60c6d631b7015e844c19e76169b653e5 455 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 243 421 1.1E-38 T 23-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L08_09410 60c6d631b7015e844c19e76169b653e5 455 TIGRFAM TIGR00414 serS: serine--tRNA ligase 1 438 2.4E-161 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A3L08_09410 60c6d631b7015e844c19e76169b653e5 455 SUPERFAMILY SSF46589 1 115 7.32E-28 T 23-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 A3L08_09410 60c6d631b7015e844c19e76169b653e5 455 PIRSF PIRSF001529 1 447 4.3E-154 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A3L08_09410 60c6d631b7015e844c19e76169b653e5 455 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 443 41.585 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A3L08_09410 60c6d631b7015e844c19e76169b653e5 455 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 109 1.4E-27 T 23-10-2018 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: R-HSA-2408557|Reactome: R-HSA-379716 A3L08_09410 60c6d631b7015e844c19e76169b653e5 455 SUPERFAMILY SSF55681 154 446 1.26E-87 T 23-10-2018 A3L08_09410 60c6d631b7015e844c19e76169b653e5 455 Gene3D G3DSA:3.30.930.10 108 455 2.1E-135 T 23-10-2018 A3L08_06650 27809cc211fdce96a59a8f98cb7eb827 212 SUPERFAMILY SSF46785 6 80 5.79E-15 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L08_06650 27809cc211fdce96a59a8f98cb7eb827 212 SMART SM00347 1 101 0.0044 T 23-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A3L08_06650 27809cc211fdce96a59a8f98cb7eb827 212 SMART SM00419 14 66 1.1E-4 T 23-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 A3L08_06650 27809cc211fdce96a59a8f98cb7eb827 212 Gene3D G3DSA:1.10.10.10 1 83 7.7E-17 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L08_06650 27809cc211fdce96a59a8f98cb7eb827 212 Gene3D G3DSA:2.40.30.30 85 212 1.6E-39 T 23-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 A3L08_06650 27809cc211fdce96a59a8f98cb7eb827 212 Pfam PF13545 Crp-like helix-turn-helix domain 6 64 1.5E-8 T 23-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 A3L08_06650 27809cc211fdce96a59a8f98cb7eb827 212 Pfam PF01982 Domain of unknown function DUF120 92 209 1.6E-36 T 23-10-2018 IPR023602 Riboflavin kinase domain, CTP-dependent GO:0016773 KEGG: 00740+2.7.1.161|MetaCyc: PWY-6167 A3L08_06650 27809cc211fdce96a59a8f98cb7eb827 212 SUPERFAMILY SSF82114 87 209 4.58E-39 T 23-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 A3L08_06650 27809cc211fdce96a59a8f98cb7eb827 212 Hamap MF_01285 Riboflavin kinase [ribK]. 86 209 24.763 T 23-10-2018 IPR023470 Riboflavin kinase, archaeal GO:0008531|GO:0009231 KEGG: 00740+2.7.1.161|MetaCyc: PWY-6167 A3L08_03785 e96ee4fb4ddd7c8d5ac5beeca2d1fab5 138 Pfam PF03061 Thioesterase superfamily 40 92 2.2E-7 T 23-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 A3L08_03785 e96ee4fb4ddd7c8d5ac5beeca2d1fab5 138 Gene3D G3DSA:3.10.129.10 1 138 2.9E-41 T 23-10-2018 A3L08_03785 e96ee4fb4ddd7c8d5ac5beeca2d1fab5 138 SUPERFAMILY SSF54637 13 129 5.13E-25 T 23-10-2018 IPR029069 HotDog domain superfamily A3L08_01455 85c46f0544bc291d0a675bd116374a0b 420 Pfam PF13450 NAD(P)-binding Rossmann-like domain 5 69 3.0E-12 T 23-10-2018 A3L08_01455 85c46f0544bc291d0a675bd116374a0b 420 Gene3D G3DSA:3.50.50.60 4 403 2.7E-142 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L08_01455 85c46f0544bc291d0a675bd116374a0b 420 SUPERFAMILY SSF51905 3 319 5.99E-36 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L08_01455 85c46f0544bc291d0a675bd116374a0b 420 PRINTS PR00419 Adrenodoxin reductase family signature 2 24 6.0E-5 T 23-10-2018 A3L08_01455 85c46f0544bc291d0a675bd116374a0b 420 PRINTS PR00419 Adrenodoxin reductase family signature 25 38 6.0E-5 T 23-10-2018 A3L08_01455 85c46f0544bc291d0a675bd116374a0b 420 Gene3D G3DSA:3.90.660.50 83 359 2.7E-142 T 23-10-2018 A3L08_04470 04934a4daed6428eb948d7626ec4bd8d 441 PIRSF PIRSF001413 6 430 1.6E-157 T 23-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A3L08_04470 04934a4daed6428eb948d7626ec4bd8d 441 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 103 117 - T 23-10-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A3L08_04470 04934a4daed6428eb948d7626ec4bd8d 441 PIRSF PIRSF500824 1 433 1.1E-212 T 23-10-2018 IPR006316 Tryptophan synthase, beta chain-like GO:0000162|GO:0004834|GO:0030170 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A3L08_04470 04934a4daed6428eb948d7626ec4bd8d 441 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 18 424 42.65 T 23-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A3L08_04470 04934a4daed6428eb948d7626ec4bd8d 441 Gene3D G3DSA:3.40.50.1100 11 236 6.0E-178 T 23-10-2018 A3L08_04470 04934a4daed6428eb948d7626ec4bd8d 441 Gene3D G3DSA:3.40.50.1100 10 417 6.0E-178 T 23-10-2018 A3L08_04470 04934a4daed6428eb948d7626ec4bd8d 441 SUPERFAMILY SSF53686 24 423 2.75E-111 T 23-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme A3L08_04470 04934a4daed6428eb948d7626ec4bd8d 441 TIGRFAM TIGR01415 trpB_rel: pyridoxal-phosphate dependent TrpB-like enzyme 10 426 1.4E-219 T 23-10-2018 IPR006316 Tryptophan synthase, beta chain-like GO:0000162|GO:0004834|GO:0030170 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A3L08_04470 04934a4daed6428eb948d7626ec4bd8d 441 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 75 411 3.5E-45 T 23-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme A3L08_03995 cec99c1df426977d7d809277289f521f 600 SUPERFAMILY SSF52833 7 98 1.45E-20 T 23-10-2018 IPR036249 Thioredoxin-like superfamily A3L08_03995 cec99c1df426977d7d809277289f521f 600 Gene3D G3DSA:3.10.20.600 342 436 5.1E-33 T 23-10-2018 A3L08_03995 cec99c1df426977d7d809277289f521f 600 Gene3D G3DSA:3.30.70.20 543 592 1.6E-12 T 23-10-2018 A3L08_03995 cec99c1df426977d7d809277289f521f 600 Pfam PF10531 SLBB domain 353 401 6.1E-9 T 23-10-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L08_03995 cec99c1df426977d7d809277289f521f 600 SUPERFAMILY SSF142019 112 350 1.29E-96 T 23-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L08_03995 cec99c1df426977d7d809277289f521f 600 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 440 524 3.4E-31 T 23-10-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L08_03995 cec99c1df426977d7d809277289f521f 600 SUPERFAMILY SSF54862 540 596 6.58E-14 T 23-10-2018 A3L08_03995 cec99c1df426977d7d809277289f521f 600 Gene3D G3DSA:1.20.1440.230 437 538 1.6E-33 T 23-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L08_03995 cec99c1df426977d7d809277289f521f 600 Gene3D G3DSA:3.40.30.10 5 97 4.5E-21 T 23-10-2018 A3L08_03995 cec99c1df426977d7d809277289f521f 600 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 160 329 4.5E-50 T 23-10-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L08_03995 cec99c1df426977d7d809277289f521f 600 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 547 558 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L08_03995 cec99c1df426977d7d809277289f521f 600 SUPERFAMILY SSF140490 435 531 1.83E-36 T 23-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L08_03995 cec99c1df426977d7d809277289f521f 600 Pfam PF00037 4Fe-4S binding domain 540 562 1.1E-4 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L08_03995 cec99c1df426977d7d809277289f521f 600 Pfam PF00037 4Fe-4S binding domain 571 593 1.2E-7 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L08_03995 cec99c1df426977d7d809277289f521f 600 SMART SM00928 439 484 2.8E-23 T 23-10-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L08_03995 cec99c1df426977d7d809277289f521f 600 Gene3D G3DSA:3.40.50.11540 163 341 3.4E-84 T 23-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L08_03995 cec99c1df426977d7d809277289f521f 600 SUPERFAMILY SSF142984 351 434 1.83E-25 T 23-10-2018 A3L08_02235 8ad2baf3e10f6b7706c3763d129fa974 499 PIRSF PIRSF006615 5 499 5.3E-201 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A3L08_02235 8ad2baf3e10f6b7706c3763d129fa974 499 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 336 355 1.2E-87 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A3L08_02235 8ad2baf3e10f6b7706c3763d129fa974 499 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 296 312 1.2E-87 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A3L08_02235 8ad2baf3e10f6b7706c3763d129fa974 499 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 450 468 1.2E-87 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A3L08_02235 8ad2baf3e10f6b7706c3763d129fa974 499 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 269 288 1.2E-87 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A3L08_02235 8ad2baf3e10f6b7706c3763d129fa974 499 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 405 426 1.2E-87 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A3L08_02235 8ad2baf3e10f6b7706c3763d129fa974 499 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 249 268 1.2E-87 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A3L08_02235 8ad2baf3e10f6b7706c3763d129fa974 499 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 150 170 1.2E-87 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A3L08_02235 8ad2baf3e10f6b7706c3763d129fa974 499 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 232 248 1.2E-87 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A3L08_02235 8ad2baf3e10f6b7706c3763d129fa974 499 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 382 399 1.2E-87 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A3L08_02235 8ad2baf3e10f6b7706c3763d129fa974 499 Gene3D G3DSA:1.10.1370.30 1 499 6.3E-201 T 23-10-2018 A3L08_02235 8ad2baf3e10f6b7706c3763d129fa974 499 Pfam PF02074 Carboxypeptidase Taq (M32) metallopeptidase 11 498 5.5E-109 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A3L08_02235 8ad2baf3e10f6b7706c3763d129fa974 499 SUPERFAMILY SSF55486 7 499 9.89E-117 T 23-10-2018 A3L08_02020 4d5735abfbf4fe9b26a49770c35875fd 415 Gene3D G3DSA:1.10.8.60 19 295 5.1E-109 T 23-10-2018 A3L08_02020 4d5735abfbf4fe9b26a49770c35875fd 415 SUPERFAMILY SSF52540 19 291 6.93E-56 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_02020 4d5735abfbf4fe9b26a49770c35875fd 415 Hamap MF_01407 ORC1-type DNA replication protein. 12 394 34.145 T 23-10-2018 IPR014277 Orc1/Cdc6-type DNA replication protein, archaea A3L08_02020 4d5735abfbf4fe9b26a49770c35875fd 415 SMART SM01074 312 393 8.3E-36 T 23-10-2018 IPR015163 Cdc6, C-terminal Reactome: R-HSA-176187|Reactome: R-HSA-539107|Reactome: R-HSA-68689|Reactome: R-HSA-68827|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962 A3L08_02020 4d5735abfbf4fe9b26a49770c35875fd 415 SMART SM00382 57 218 1.7E-11 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L08_02020 4d5735abfbf4fe9b26a49770c35875fd 415 Gene3D G3DSA:1.10.10.10 304 405 1.9E-33 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L08_02020 4d5735abfbf4fe9b26a49770c35875fd 415 SUPERFAMILY SSF46785 297 401 5.89E-31 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L08_02020 4d5735abfbf4fe9b26a49770c35875fd 415 Pfam PF13191 AAA ATPase domain 35 175 2.6E-9 T 23-10-2018 A3L08_02020 4d5735abfbf4fe9b26a49770c35875fd 415 TIGRFAM TIGR02928 TIGR02928: orc1/cdc6 family replication initiation protein 19 383 1.9E-150 T 23-10-2018 IPR014277 Orc1/Cdc6-type DNA replication protein, archaea A3L08_02020 4d5735abfbf4fe9b26a49770c35875fd 415 Gene3D G3DSA:3.40.50.300 35 216 5.1E-109 T 23-10-2018 A3L08_02020 4d5735abfbf4fe9b26a49770c35875fd 415 Pfam PF09079 CDC6, C terminal winged helix domain 312 391 2.1E-26 T 23-10-2018 IPR015163 Cdc6, C-terminal Reactome: R-HSA-176187|Reactome: R-HSA-539107|Reactome: R-HSA-68689|Reactome: R-HSA-68827|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962 A3L08_00405 a06fb7eb9026ef898e175788a686dbd3 135 Pfam PF01842 ACT domain 59 124 2.5E-10 T 23-10-2018 IPR002912 ACT domain A3L08_00405 a06fb7eb9026ef898e175788a686dbd3 135 SUPERFAMILY SSF55021 60 131 3.72E-12 T 23-10-2018 A3L08_00405 a06fb7eb9026ef898e175788a686dbd3 135 Gene3D G3DSA:3.30.70.260 47 131 3.3E-11 T 23-10-2018 A3L08_00405 a06fb7eb9026ef898e175788a686dbd3 135 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 65 130 0.01 T 23-10-2018 A3L08_02130 f4124b570cef854d9151c96b6c9b2313 225 Gene3D G3DSA:3.90.850.10 2 221 1.6E-91 T 23-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 A3L08_02130 f4124b570cef854d9151c96b6c9b2313 225 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 17 217 1.8E-70 T 23-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 A3L08_02130 f4124b570cef854d9151c96b6c9b2313 225 SUPERFAMILY SSF56529 12 221 4.32E-82 T 23-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 A3L08_08680 0c7a87fa5f487c85fef53271c38622a0 318 Pfam PF03747 ADP-ribosylglycohydrolase 13 290 4.7E-68 T 23-10-2018 IPR005502 ADP-ribosylation/Crystallin J1 A3L08_08680 0c7a87fa5f487c85fef53271c38622a0 318 Gene3D G3DSA:1.10.4080.10 5 315 5.8E-85 T 23-10-2018 IPR036705 ADP-ribosylation/Crystallin J1 superfamily A3L08_08680 0c7a87fa5f487c85fef53271c38622a0 318 SUPERFAMILY SSF101478 5 309 1.29E-72 T 23-10-2018 IPR036705 ADP-ribosylation/Crystallin J1 superfamily A3L08_03240 af40943b7869e406cb33776647bb4ad9 334 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 2 321 3.0E-125 T 23-10-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A3L08_03240 af40943b7869e406cb33776647bb4ad9 334 Pfam PF00586 AIR synthase related protein, N-terminal domain 57 159 7.2E-19 T 23-10-2018 IPR016188 PurM-like, N-terminal domain A3L08_03240 af40943b7869e406cb33776647bb4ad9 334 Gene3D G3DSA:3.30.1330.10 2 165 2.2E-52 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A3L08_03240 af40943b7869e406cb33776647bb4ad9 334 Pfam PF02769 AIR synthase related protein, C-terminal domain 171 327 2.1E-25 T 23-10-2018 IPR010918 PurM-like, C-terminal domain A3L08_03240 af40943b7869e406cb33776647bb4ad9 334 Gene3D G3DSA:3.90.650.10 166 334 1.2E-50 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A3L08_03240 af40943b7869e406cb33776647bb4ad9 334 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 2 330 38.118 T 23-10-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A3L08_03240 af40943b7869e406cb33776647bb4ad9 334 SUPERFAMILY SSF56042 166 327 6.73E-44 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A3L08_03240 af40943b7869e406cb33776647bb4ad9 334 SUPERFAMILY SSF55326 2 165 1.09E-40 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A3L08_04335 bc18f47999b9d00f2dd81d8c3ede9ede 448 Gene3D G3DSA:1.20.120.140 6 305 6.6E-123 T 23-10-2018 A3L08_04335 bc18f47999b9d00f2dd81d8c3ede9ede 448 Gene3D G3DSA:3.40.50.300 91 284 6.6E-123 T 23-10-2018 A3L08_04335 bc18f47999b9d00f2dd81d8c3ede9ede 448 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 6 438 38.083 T 23-10-2018 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 A3L08_04335 bc18f47999b9d00f2dd81d8c3ede9ede 448 SUPERFAMILY SSF47446 297 429 2.62E-43 T 23-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 A3L08_04335 bc18f47999b9d00f2dd81d8c3ede9ede 448 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 268 281 - T 23-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A3L08_04335 bc18f47999b9d00f2dd81d8c3ede9ede 448 SMART SM00962 100 295 8.3E-101 T 23-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A3L08_04335 bc18f47999b9d00f2dd81d8c3ede9ede 448 SMART SM00963 2 87 3.9E-23 T 23-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A3L08_04335 bc18f47999b9d00f2dd81d8c3ede9ede 448 Pfam PF00448 SRP54-type protein, GTPase domain 100 295 2.8E-75 T 23-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A3L08_04335 bc18f47999b9d00f2dd81d8c3ede9ede 448 Gene3D G3DSA:1.10.260.30 309 435 1.8E-45 T 23-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 A3L08_04335 bc18f47999b9d00f2dd81d8c3ede9ede 448 Pfam PF02881 SRP54-type protein, helical bundle domain 6 83 5.5E-20 T 23-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A3L08_04335 bc18f47999b9d00f2dd81d8c3ede9ede 448 SUPERFAMILY SSF47364 1 94 4.71E-23 T 23-10-2018 IPR036225 SRP/SRP receptor, N-terminal Reactome: R-HSA-1799339 A3L08_04335 bc18f47999b9d00f2dd81d8c3ede9ede 448 SMART SM00382 99 300 7.1E-6 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L08_04335 bc18f47999b9d00f2dd81d8c3ede9ede 448 SUPERFAMILY SSF52540 96 297 4.62E-50 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_04335 bc18f47999b9d00f2dd81d8c3ede9ede 448 Pfam PF02978 Signal peptide binding domain 327 425 7.8E-34 T 23-10-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 A3L08_04285 af591355abd01fafc07d9e744dbf60b9 52 Gene3D G3DSA:2.20.28.70 1 49 6.3E-19 T 23-10-2018 IPR038587 Ribosomal protein L40e superfamily Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 A3L08_04285 af591355abd01fafc07d9e744dbf60b9 52 SUPERFAMILY SSF57829 2 46 5.49E-16 T 23-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 A3L08_04285 af591355abd01fafc07d9e744dbf60b9 52 SMART SM01377 1 46 8.2E-9 T 23-10-2018 IPR001975 Ribosomal protein L40e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 A3L08_04285 af591355abd01fafc07d9e744dbf60b9 52 Hamap MF_00788 50S ribosomal protein L40e [rpl40e]. 2 47 19.648 T 23-10-2018 IPR023657 Ribosomal protein L40e, archaeal GO:0003735|GO:0005840|GO:0006412 A3L08_09260 ea1cc086b9f439ef0f22b8f5cd264653 281 Pfam PF00589 Phage integrase family 99 262 2.5E-51 T 23-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 A3L08_09260 ea1cc086b9f439ef0f22b8f5cd264653 281 SUPERFAMILY SSF56349 6 270 4.41E-60 T 23-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A3L08_09260 ea1cc086b9f439ef0f22b8f5cd264653 281 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 8 77 3.6E-8 T 23-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 A3L08_09260 ea1cc086b9f439ef0f22b8f5cd264653 281 Gene3D G3DSA:1.10.150.130 3 90 2.2E-20 T 23-10-2018 IPR010998 Integrase/recombinase, N-terminal A3L08_09260 ea1cc086b9f439ef0f22b8f5cd264653 281 Hamap MF_02055 Tyrosine recombinase XerA [xerA]. 4 274 42.906 T 23-10-2018 IPR033686 Tyrosine recombinase XerA A3L08_09260 ea1cc086b9f439ef0f22b8f5cd264653 281 Gene3D G3DSA:1.10.443.10 91 281 2.1E-76 T 23-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 A3L08_06380 ee8e1701c1644bd0bbc0c46c2d6a7401 151 SUPERFAMILY SSF47060 66 142 1.32E-24 T 23-10-2018 IPR009068 S15/NS1, RNA-binding A3L08_06380 ee8e1701c1644bd0bbc0c46c2d6a7401 151 SMART SM01386 1 60 6.0E-34 T 23-10-2018 IPR012606 Ribosomal protein S13/S15, N-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_06380 ee8e1701c1644bd0bbc0c46c2d6a7401 151 ProSitePatterns PS00362 Ribosomal protein S15 signature. 98 128 - T 23-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L08_06380 ee8e1701c1644bd0bbc0c46c2d6a7401 151 Hamap MF_01343_A 30S ribosomal protein S15 [rpsO]. 3 149 37.353 T 23-10-2018 IPR023029 Ribosomal protein S15P Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_06380 ee8e1701c1644bd0bbc0c46c2d6a7401 151 Pfam PF08069 Ribosomal S13/S15 N-terminal domain 1 60 9.2E-27 T 23-10-2018 IPR012606 Ribosomal protein S13/S15, N-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_06380 ee8e1701c1644bd0bbc0c46c2d6a7401 151 Gene3D G3DSA:1.10.8.1030 36 82 6.7E-21 T 23-10-2018 A3L08_06380 ee8e1701c1644bd0bbc0c46c2d6a7401 151 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 91 133 3.0E-4 T 23-10-2018 A3L08_06380 ee8e1701c1644bd0bbc0c46c2d6a7401 151 Gene3D G3DSA:1.10.287.10 83 151 5.8E-32 T 23-10-2018 A3L08_06380 ee8e1701c1644bd0bbc0c46c2d6a7401 151 Pfam PF00312 Ribosomal protein S15 73 148 8.1E-20 T 23-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L08_06380 ee8e1701c1644bd0bbc0c46c2d6a7401 151 SMART SM01387 70 149 9.9E-26 T 23-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L08_01500 10d3ce80454b274bdf832a8a0bae8b76 183 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 183 27.935 T 23-10-2018 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A3L08_01500 10d3ce80454b274bdf832a8a0bae8b76 183 Pfam PF00156 Phosphoribosyl transferase domain 35 156 2.0E-21 T 23-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 A3L08_01500 10d3ce80454b274bdf832a8a0bae8b76 183 SUPERFAMILY SSF53271 4 162 1.84E-45 T 23-10-2018 IPR029057 Phosphoribosyltransferase-like A3L08_01500 10d3ce80454b274bdf832a8a0bae8b76 183 TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase 12 171 1.1E-50 T 23-10-2018 IPR004467 Orotate phosphoribosyl transferase domain GO:0004588 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A3L08_01500 10d3ce80454b274bdf832a8a0bae8b76 183 Gene3D G3DSA:3.40.50.2020 1 176 7.6E-58 T 23-10-2018 A3L08_04295 0dec099de28ca9d926f798bdf6178e83 99 Pfam PF04930 FUN14 family 12 96 6.6E-15 T 23-10-2018 IPR007014 FUN14 A3L08_04950 87952d3bee1a7bb75c790d0d6f10b032 496 Pfam PF04324 BFD-like [2Fe-2S] binding domain 406 464 6.2E-16 T 23-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain A3L08_04950 87952d3bee1a7bb75c790d0d6f10b032 496 Gene3D G3DSA:1.10.10.1100 393 472 4.5E-18 T 23-10-2018 A3L08_04950 87952d3bee1a7bb75c790d0d6f10b032 496 SUPERFAMILY SSF51905 3 390 3.8E-56 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L08_04950 87952d3bee1a7bb75c790d0d6f10b032 496 Gene3D G3DSA:3.30.9.10 90 321 4.5E-114 T 23-10-2018 A3L08_04950 87952d3bee1a7bb75c790d0d6f10b032 496 Pfam PF01266 FAD dependent oxidoreductase 4 360 4.1E-67 T 23-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 A3L08_04950 87952d3bee1a7bb75c790d0d6f10b032 496 SUPERFAMILY SSF54373 223 318 4.05E-8 T 23-10-2018 A3L08_04950 87952d3bee1a7bb75c790d0d6f10b032 496 Gene3D G3DSA:3.50.50.60 5 354 4.5E-114 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L08_07245 6df45250166579acd31fa59c9f85b077 659 Pfam PF02421 Ferrous iron transport protein B 5 160 1.8E-64 T 23-10-2018 IPR030389 FeoB-type guanine nucleotide-binding (G) domain GO:0005525 A3L08_07245 6df45250166579acd31fa59c9f85b077 659 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 3 159 1.5E-12 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A3L08_07245 6df45250166579acd31fa59c9f85b077 659 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 27 45 2.1E-6 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L08_07245 6df45250166579acd31fa59c9f85b077 659 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 6 26 2.1E-6 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L08_07245 6df45250166579acd31fa59c9f85b077 659 Pfam PF07664 Ferrous iron transport protein B C terminus 458 510 1.4E-18 T 23-10-2018 IPR011640 Ferrous iron transport protein B, C-terminal GO:0015093|GO:0015684|GO:0016021 A3L08_07245 6df45250166579acd31fa59c9f85b077 659 Gene3D G3DSA:3.40.50.300 1 169 1.4E-48 T 23-10-2018 A3L08_07245 6df45250166579acd31fa59c9f85b077 659 Pfam PF07670 Nucleoside recognition 354 443 9.1E-13 T 23-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 A3L08_07245 6df45250166579acd31fa59c9f85b077 659 Pfam PF07670 Nucleoside recognition 515 629 2.4E-27 T 23-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 A3L08_07245 6df45250166579acd31fa59c9f85b077 659 TIGRFAM TIGR00437 feoB: ferrous iron transport protein B 10 626 1.2E-188 T 23-10-2018 IPR003373 Ferrous iron transport protein B GO:0005525|GO:0015093|GO:0015684|GO:0016021 A3L08_07245 6df45250166579acd31fa59c9f85b077 659 SUPERFAMILY SSF52540 6 179 1.87E-43 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_00485 8ed4ada7efbf53f3f01c85eaea1f8cf0 190 Pfam PF00352 Transcription factor TFIID (or TATA-binding protein, TBP) 100 181 1.3E-28 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 A3L08_00485 8ed4ada7efbf53f3f01c85eaea1f8cf0 190 Pfam PF00352 Transcription factor TFIID (or TATA-binding protein, TBP) 9 89 9.7E-28 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 A3L08_00485 8ed4ada7efbf53f3f01c85eaea1f8cf0 190 Hamap MF_00408 TATA-box-binding protein [tbp]. 5 184 37.739 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 A3L08_00485 8ed4ada7efbf53f3f01c85eaea1f8cf0 190 SUPERFAMILY SSF55945 96 182 2.36E-30 T 23-10-2018 A3L08_00485 8ed4ada7efbf53f3f01c85eaea1f8cf0 190 PRINTS PR00686 Transcription initiation factor TFIID signature 125 140 1.0E-43 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 A3L08_00485 8ed4ada7efbf53f3f01c85eaea1f8cf0 190 PRINTS PR00686 Transcription initiation factor TFIID signature 35 54 1.0E-43 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 A3L08_00485 8ed4ada7efbf53f3f01c85eaea1f8cf0 190 PRINTS PR00686 Transcription initiation factor TFIID signature 102 118 1.0E-43 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 A3L08_00485 8ed4ada7efbf53f3f01c85eaea1f8cf0 190 PRINTS PR00686 Transcription initiation factor TFIID signature 144 160 1.0E-43 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 A3L08_00485 8ed4ada7efbf53f3f01c85eaea1f8cf0 190 PRINTS PR00686 Transcription initiation factor TFIID signature 11 26 1.0E-43 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 A3L08_00485 8ed4ada7efbf53f3f01c85eaea1f8cf0 190 PRINTS PR00686 Transcription initiation factor TFIID signature 54 72 1.0E-43 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 A3L08_00485 8ed4ada7efbf53f3f01c85eaea1f8cf0 190 SUPERFAMILY SSF55945 5 94 4.24E-29 T 23-10-2018 A3L08_00485 8ed4ada7efbf53f3f01c85eaea1f8cf0 190 ProSitePatterns PS00351 Transcription factor TFIID repeat signature. 129 178 - T 23-10-2018 IPR030491 TATA-box binding protein, conserved site A3L08_00485 8ed4ada7efbf53f3f01c85eaea1f8cf0 190 Gene3D G3DSA:3.30.310.10 16 98 7.6E-33 T 23-10-2018 IPR012295 TBP domain superfamily A3L08_00485 8ed4ada7efbf53f3f01c85eaea1f8cf0 190 Gene3D G3DSA:3.30.310.10 99 182 4.3E-35 T 23-10-2018 IPR012295 TBP domain superfamily A3L08_05530 d5ea7c258bd0efa63a8b6f2e3486b334 177 Pfam PF01928 CYTH domain 2 169 5.3E-34 T 23-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 A3L08_05530 d5ea7c258bd0efa63a8b6f2e3486b334 177 SMART SM01118 1 175 1.7E-24 T 23-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 A3L08_05530 d5ea7c258bd0efa63a8b6f2e3486b334 177 ProDom PD009560 CYCLASE ADENYLATE CYCLASE ADENYLYL CYAB LYASE CLASS CYAB-TYPE THERMOPHILIC MJ0240 1 152 4.0E-65 T 23-10-2018 A3L08_05530 d5ea7c258bd0efa63a8b6f2e3486b334 177 TIGRFAM TIGR00318 cyaB: putative adenylyl cyclase CyaB 2 173 1.1E-44 T 23-10-2018 IPR008173 Adenylyl cyclase CyaB KEGG: 00230+4.6.1.1 A3L08_05530 d5ea7c258bd0efa63a8b6f2e3486b334 177 SUPERFAMILY SSF55154 2 173 5.23E-37 T 23-10-2018 IPR033469 CYTH-like domain superfamily Reactome: R-HSA-196819 A3L08_05530 d5ea7c258bd0efa63a8b6f2e3486b334 177 Gene3D G3DSA:2.40.320.10 1 177 3.5E-56 T 23-10-2018 A3L08_09340 d157ef5d192a034feaca9f357cd381d5 142 Gene3D G3DSA:3.10.330.10 1 77 1.2E-25 T 23-10-2018 A3L08_09340 d157ef5d192a034feaca9f357cd381d5 142 Gene3D G3DSA:2.40.10.360 80 142 1.3E-10 T 23-10-2018 A3L08_09340 d157ef5d192a034feaca9f357cd381d5 142 Pfam PF02933 Cell division protein 48 (CDC48), domain 2 14 68 2.6E-5 T 23-10-2018 IPR004201 CDC48, domain 2 A3L08_09340 d157ef5d192a034feaca9f357cd381d5 142 SMART SM01072 12 74 2.2E-4 T 23-10-2018 IPR004201 CDC48, domain 2 A3L08_09340 d157ef5d192a034feaca9f357cd381d5 142 SUPERFAMILY SSF54585 2 73 9.81E-11 T 23-10-2018 IPR029067 CDC48 domain 2-like superfamily A3L08_03500 59b9d7e96b88b2317b86159b3be3c94b 112 Gene3D G3DSA:3.30.110.70 7 112 3.8E-30 T 23-10-2018 A3L08_03500 59b9d7e96b88b2317b86159b3be3c94b 112 SUPERFAMILY SSF117782 8 111 3.01E-35 T 23-10-2018 IPR035439 UPF0145 domain superfamily A3L08_03500 59b9d7e96b88b2317b86159b3be3c94b 112 Hamap MF_00338 UPF0145 protein YbjQ [ybjQ]. 7 109 24.566 T 23-10-2018 IPR002765 Uncharacterised protein family UPF0145 A3L08_03500 59b9d7e96b88b2317b86159b3be3c94b 112 Pfam PF01906 Putative heavy-metal-binding 7 109 1.7E-35 T 23-10-2018 IPR002765 Uncharacterised protein family UPF0145 A3L08_03865 85aac92aa90bdea98ee41d83398071e3 269 Gene3D G3DSA:3.30.230.70 1 268 1.9E-85 T 23-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A3L08_03865 85aac92aa90bdea98ee41d83398071e3 269 Pfam PF03725 3' exoribonuclease family, domain 2 189 253 8.3E-12 T 23-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A3L08_03865 85aac92aa90bdea98ee41d83398071e3 269 SUPERFAMILY SSF55666 184 268 7.4E-24 T 23-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A3L08_03865 85aac92aa90bdea98ee41d83398071e3 269 SUPERFAMILY SSF54211 10 212 3.69E-51 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A3L08_03865 85aac92aa90bdea98ee41d83398071e3 269 Pfam PF01138 3' exoribonuclease family, domain 1 30 164 4.4E-26 T 23-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A3L08_03865 85aac92aa90bdea98ee41d83398071e3 269 Hamap MF_00622 Exosome complex component Rrp42 [rrp42]. 1 265 44.744 T 23-10-2018 IPR020869 Exosome complex component Rrp42, archaea GO:0000178|GO:0006401 A3L08_05680 ce8f19d9736ba2707a83144b23866d52 350 TIGRFAM TIGR00692 tdh: L-threonine 3-dehydrogenase 7 346 5.3E-179 T 23-10-2018 IPR004627 L-threonine 3-dehydrogenase GO:0006567|GO:0008270|GO:0008743|GO:0055114 KEGG: 00260+1.1.1.103|MetaCyc: PWY-7378 A3L08_05680 ce8f19d9736ba2707a83144b23866d52 350 SMART SM00829 16 345 2.0E-6 T 23-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 A3L08_05680 ce8f19d9736ba2707a83144b23866d52 350 SUPERFAMILY SSF51735 146 310 2.37E-34 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L08_05680 ce8f19d9736ba2707a83144b23866d52 350 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 66 80 - T 23-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 A3L08_05680 ce8f19d9736ba2707a83144b23866d52 350 SUPERFAMILY SSF50129 3 177 2.59E-54 T 23-10-2018 IPR011032 GroES-like superfamily A3L08_05680 ce8f19d9736ba2707a83144b23866d52 350 Gene3D G3DSA:3.40.50.720 157 291 6.4E-135 T 23-10-2018 A3L08_05680 ce8f19d9736ba2707a83144b23866d52 350 Hamap MF_00627 L-threonine 3-dehydrogenase [tdh]. 5 347 53.783 T 23-10-2018 IPR004627 L-threonine 3-dehydrogenase GO:0006567|GO:0008270|GO:0008743|GO:0055114 KEGG: 00260+1.1.1.103|MetaCyc: PWY-7378 A3L08_05680 ce8f19d9736ba2707a83144b23866d52 350 Pfam PF00107 Zinc-binding dehydrogenase 178 306 6.2E-30 T 23-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 A3L08_05680 ce8f19d9736ba2707a83144b23866d52 350 Gene3D G3DSA:3.90.180.10 21 338 6.4E-135 T 23-10-2018 A3L08_05680 ce8f19d9736ba2707a83144b23866d52 350 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 138 1.7E-36 T 23-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 A3L08_08990 8eccf4c8df4d4cbb33d59fdcc41b7485 198 Pfam PF04289 Protein of unknown function (DUF447) 13 185 2.1E-23 T 23-10-2018 IPR007386 Protein of unknown function DUF447 A3L08_08990 8eccf4c8df4d4cbb33d59fdcc41b7485 198 PIRSF PIRSF018747 1 194 2.5E-44 T 23-10-2018 IPR016733 Uncharacterised conserved protein UCP018747 A3L08_08990 8eccf4c8df4d4cbb33d59fdcc41b7485 198 Gene3D G3DSA:1.20.58.290 60 164 4.6E-10 T 23-10-2018 A3L08_08990 8eccf4c8df4d4cbb33d59fdcc41b7485 198 SUPERFAMILY SSF50475 6 190 5.23E-29 T 23-10-2018 A3L08_08990 8eccf4c8df4d4cbb33d59fdcc41b7485 198 Gene3D G3DSA:2.30.110.10 12 130 4.6E-10 T 23-10-2018 IPR012349 FMN-binding split barrel GO:0048037 A3L08_01310 bc0e11046a09e12b407b94c0868f0725 105 Gene3D G3DSA:3.30.70.20 69 105 6.3E-10 T 23-10-2018 A3L08_01310 bc0e11046a09e12b407b94c0868f0725 105 Gene3D G3DSA:3.30.70.20 33 68 8.7E-6 T 23-10-2018 A3L08_01310 bc0e11046a09e12b407b94c0868f0725 105 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 83 94 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L08_01310 bc0e11046a09e12b407b94c0868f0725 105 Pfam PF14697 4Fe-4S dicluster domain 47 100 8.3E-11 T 23-10-2018 A3L08_01310 bc0e11046a09e12b407b94c0868f0725 105 TIGRFAM TIGR02179 PorD_KorD: 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate family 32 104 7.7E-34 T 23-10-2018 IPR011898 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate GO:0016625|GO:0051539 A3L08_01310 bc0e11046a09e12b407b94c0868f0725 105 SUPERFAMILY SSF54862 32 103 1.62E-24 T 23-10-2018 A3L08_04450 cd13c255493212f6034c684f1860f38b 358 Gene3D G3DSA:3.40.350.10 1 131 6.2E-32 T 23-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal A3L08_04450 cd13c255493212f6034c684f1860f38b 358 SUPERFAMILY SSF55920 132 357 3.53E-76 T 23-10-2018 IPR036005 Creatinase/aminopeptidase-like A3L08_04450 cd13c255493212f6034c684f1860f38b 358 Pfam PF01321 Creatinase/Prolidase N-terminal domain 2 133 1.9E-19 T 23-10-2018 IPR000587 Creatinase, N-terminal GO:0016787 A3L08_04450 cd13c255493212f6034c684f1860f38b 358 Pfam PF00557 Metallopeptidase family M24 141 340 4.6E-68 T 23-10-2018 IPR000994 Peptidase M24 A3L08_04450 cd13c255493212f6034c684f1860f38b 358 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 288 300 - T 23-10-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site A3L08_04450 cd13c255493212f6034c684f1860f38b 358 SUPERFAMILY SSF53092 2 131 3.49E-17 T 23-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal A3L08_04450 cd13c255493212f6034c684f1860f38b 358 Gene3D G3DSA:3.90.230.10 133 357 5.6E-82 T 23-10-2018 A3L08_05045 756f5002734fd1b51b1a2d304ece8a98 391 SUPERFAMILY SSF64484 27 385 1.56E-106 T 23-10-2018 A3L08_05045 756f5002734fd1b51b1a2d304ece8a98 391 TIGRFAM TIGR02389 RNA_pol_rpoA2: DNA-directed RNA polymerase, subunit A'' 16 382 5.2E-150 T 23-10-2018 IPR012757 DNA-directed RNA polymerase subunit A'' GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L08_05045 756f5002734fd1b51b1a2d304ece8a98 391 Hamap MF_00411 DNA-directed RNA polymerase subunit A'' [rpoA2]. 3 385 40.88 T 23-10-2018 IPR012757 DNA-directed RNA polymerase subunit A'' GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L08_05045 756f5002734fd1b51b1a2d304ece8a98 391 Gene3D G3DSA:1.10.150.390 333 378 1.0E-22 T 23-10-2018 A3L08_05045 756f5002734fd1b51b1a2d304ece8a98 391 Pfam PF04998 RNA polymerase Rpb1, domain 5 28 332 1.1E-56 T 23-10-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L08_09465 c906feb6a5569c4df1e350825cd0da14 112 SUPERFAMILY SSF46950 8 111 8.89E-28 T 23-10-2018 IPR036883 PDCD5-like superfamily GO:0003677 A3L08_09465 c906feb6a5569c4df1e350825cd0da14 112 Gene3D G3DSA:1.10.8.140 24 112 1.3E-25 T 23-10-2018 IPR036883 PDCD5-like superfamily GO:0003677 A3L08_09465 c906feb6a5569c4df1e350825cd0da14 112 Pfam PF01984 Double-stranded DNA-binding domain 8 111 6.4E-27 T 23-10-2018 IPR002836 PDCD5-like GO:0003677 A3L08_09465 c906feb6a5569c4df1e350825cd0da14 112 PIRSF PIRSF015730 1 112 7.2E-34 T 23-10-2018 IPR002836 PDCD5-like GO:0003677 A3L08_09465 c906feb6a5569c4df1e350825cd0da14 112 Hamap MF_00026 DNA-binding protein . 3 112 15.995 T 23-10-2018 IPR022889 DNA-binding protein, archaeal A3L08_02320 26e5a48626cbc750648677d1f639ecc3 239 Gene3D G3DSA:3.40.720.10 51 229 1.4E-6 T 23-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 A3L08_02320 26e5a48626cbc750648677d1f639ecc3 239 SUPERFAMILY SSF53649 122 211 4.71E-7 T 23-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 A3L08_02320 26e5a48626cbc750648677d1f639ecc3 239 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 74 202 4.8E-6 T 23-10-2018 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 A3L08_06875 292e10a072d015b86f6087b971b7ec67 200 Pfam PF02517 CAAX protease self-immunity 111 188 7.3E-10 T 23-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 A3L08_00655 62a89408f50f0eb323f354659911fcf6 578 Gene3D G3DSA:3.60.10.10 352 578 3.8E-32 T 23-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily A3L08_00655 62a89408f50f0eb323f354659911fcf6 578 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 371 568 1.7E-7 T 23-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase A3L08_00655 62a89408f50f0eb323f354659911fcf6 578 SUPERFAMILY SSF56219 349 576 3.66E-31 T 23-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily A3L08_04045 ec8a0937c0f2d4247828af3c195fc7f3 347 TIGRFAM TIGR03626 L3_arch: ribosomal protein uL3 5 346 1.5E-135 T 23-10-2018 IPR019928 Ribosomal protein L3, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L08_04045 ec8a0937c0f2d4247828af3c195fc7f3 347 Gene3D G3DSA:4.10.960.10 6 257 6.3E-123 T 23-10-2018 A3L08_04045 ec8a0937c0f2d4247828af3c195fc7f3 347 Gene3D G3DSA:2.40.30.10 39 326 6.3E-123 T 23-10-2018 A3L08_04045 ec8a0937c0f2d4247828af3c195fc7f3 347 Hamap MF_01325_A 50S ribosomal protein L3 [rplC]. 1 347 49.137 T 23-10-2018 IPR019928 Ribosomal protein L3, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L08_04045 ec8a0937c0f2d4247828af3c195fc7f3 347 ProSitePatterns PS00474 Ribosomal protein L3 signature. 193 216 - T 23-10-2018 IPR019926 Ribosomal protein L3, conserved site A3L08_04045 ec8a0937c0f2d4247828af3c195fc7f3 347 SUPERFAMILY SSF50447 3 347 5.3E-95 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily A3L08_04045 ec8a0937c0f2d4247828af3c195fc7f3 347 Pfam PF00297 Ribosomal protein L3 3 347 6.6E-90 T 23-10-2018 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L08_04045 ec8a0937c0f2d4247828af3c195fc7f3 347 Gene3D G3DSA:3.30.1430.10 77 188 6.3E-123 T 23-10-2018 A3L08_06655 a05e50dd12e9db798ffbea620ed431bb 188 Gene3D G3DSA:3.30.2170.10 2 147 7.5E-36 T 23-10-2018 A3L08_06655 a05e50dd12e9db798ffbea620ed431bb 188 Pfam PF04493 Endonuclease V 15 140 6.5E-31 T 23-10-2018 IPR007581 Endonuclease V GO:0004519|GO:0006281 A3L08_05305 37396d356d5502db8d5f7802ca773b00 244 Hamap MF_02040 Iron-sulfur cluster carrier protein. 14 238 28.521 T 23-10-2018 IPR019591 Mrp/NBP35 ATP-binding protein A3L08_05305 37396d356d5502db8d5f7802ca773b00 244 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 18 243 2.4E-55 T 23-10-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 A3L08_05305 37396d356d5502db8d5f7802ca773b00 244 Gene3D G3DSA:3.40.50.300 2 226 9.8E-68 T 23-10-2018 A3L08_05305 37396d356d5502db8d5f7802ca773b00 244 SUPERFAMILY SSF52540 20 244 1.21E-42 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_05890 0e25de746882ca438722a96983b6c430 411 Gene3D G3DSA:3.30.70.2130 81 230 4.5E-144 T 23-10-2018 A3L08_05890 0e25de746882ca438722a96983b6c430 411 SUPERFAMILY SSF53649 5 404 5.89E-46 T 23-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 A3L08_05890 0e25de746882ca438722a96983b6c430 411 Pfam PF10143 2,3-bisphosphoglycerate-independent phosphoglycerate mutase 40 208 1.9E-54 T 23-10-2018 IPR004456 2,3-bisphosphoglycerate-independent phosphoglycerate mutase GO:0003824|GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L08_05890 0e25de746882ca438722a96983b6c430 411 TIGRFAM TIGR00306 apgM: phosphoglycerate mutase (2,3-diphosphoglycerate-independent), archaeal form 7 401 7.4E-136 T 23-10-2018 IPR004456 2,3-bisphosphoglycerate-independent phosphoglycerate mutase GO:0003824|GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L08_05890 0e25de746882ca438722a96983b6c430 411 Gene3D G3DSA:3.40.720.10 7 397 4.5E-144 T 23-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 A3L08_05890 0e25de746882ca438722a96983b6c430 411 Hamap MF_01402_A 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [apgM]. 4 402 45.654 T 23-10-2018 IPR023665 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, prokaryotes GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L08_05890 0e25de746882ca438722a96983b6c430 411 Pfam PF01676 Metalloenzyme superfamily 5 400 7.0E-56 T 23-10-2018 IPR006124 Metalloenzyme GO:0003824|GO:0046872 A3L08_05890 0e25de746882ca438722a96983b6c430 411 PIRSF PIRSF006392 1 407 2.5E-156 T 23-10-2018 IPR004456 2,3-bisphosphoglycerate-independent phosphoglycerate mutase GO:0003824|GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L08_09125 4a517ea1d1478b7aa2aa29ba60e0f472 166 Gene3D G3DSA:3.40.50.1010 1 122 1.9E-42 T 23-10-2018 A3L08_09125 4a517ea1d1478b7aa2aa29ba60e0f472 166 SUPERFAMILY SSF88723 58 118 5.56E-8 T 23-10-2018 IPR029060 PIN-like domain superfamily A3L08_09125 4a517ea1d1478b7aa2aa29ba60e0f472 166 SMART SM00670 6 104 6.8E-7 T 23-10-2018 IPR002716 PIN domain A3L08_09125 4a517ea1d1478b7aa2aa29ba60e0f472 166 Gene3D G3DSA:2.20.28.10 123 160 5.3E-21 T 23-10-2018 A3L08_09125 4a517ea1d1478b7aa2aa29ba60e0f472 166 Pfam PF17146 PIN domain of ribonuclease 9 91 2.2E-19 T 23-10-2018 IPR033411 Ribonuclease, PIN domain Reactome: R-HSA-6791226 A3L08_09580 216364862c5cec8ebdf8fa4e34956279 122 SUPERFAMILY SSF81301 31 115 6.54E-18 T 23-10-2018 A3L08_09580 216364862c5cec8ebdf8fa4e34956279 122 Pfam PF01909 Nucleotidyltransferase domain 32 91 5.6E-9 T 23-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 A3L08_09580 216364862c5cec8ebdf8fa4e34956279 122 Gene3D G3DSA:3.30.460.10 26 119 2.1E-17 T 23-10-2018 A3L08_08425 bf33144b5aadd490ac24c4151955f61c 605 SUPERFAMILY SSF51569 2 301 8.97E-87 T 23-10-2018 A3L08_08425 bf33144b5aadd490ac24c4151955f61c 605 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 561 578 - T 23-10-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A3L08_08425 bf33144b5aadd490ac24c4151955f61c 605 SUPERFAMILY SSF89000 297 445 6.67E-54 T 23-10-2018 A3L08_08425 bf33144b5aadd490ac24c4151955f61c 605 Pfam PF00682 HMGL-like 3 234 6.0E-42 T 23-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 A3L08_08425 bf33144b5aadd490ac24c4151955f61c 605 Gene3D G3DSA:2.40.50.100 531 605 7.3E-29 T 23-10-2018 A3L08_08425 bf33144b5aadd490ac24c4151955f61c 605 SUPERFAMILY SSF51230 529 604 7.46E-26 T 23-10-2018 IPR011053 Single hybrid motif A3L08_08425 bf33144b5aadd490ac24c4151955f61c 605 Pfam PF00364 Biotin-requiring enzyme 539 604 2.3E-24 T 23-10-2018 IPR000089 Biotin/lipoyl attachment A3L08_08425 bf33144b5aadd490ac24c4151955f61c 605 Gene3D G3DSA:3.20.20.70 1 456 8.9E-167 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L08_08425 bf33144b5aadd490ac24c4151955f61c 605 Pfam PF02436 Conserved carboxylase domain 292 474 8.5E-58 T 23-10-2018 IPR003379 Carboxylase, conserved domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 A3L08_03560 ad2705d55c4d917f5555a5f65e0c5fa4 258 SUPERFAMILY SSF109604 51 177 7.14E-9 T 23-10-2018 A3L08_03560 ad2705d55c4d917f5555a5f65e0c5fa4 258 Gene3D G3DSA:1.10.3210.10 36 202 2.7E-7 T 23-10-2018 A3L08_03560 ad2705d55c4d917f5555a5f65e0c5fa4 258 SMART SM00471 48 181 0.0056 T 23-10-2018 IPR003607 HD/PDEase domain A3L08_03265 7a9fb3a4e94db5d9b1bd2dc402042dc4 80 Pfam PF02700 Phosphoribosylformylglycinamidine (FGAM) synthase 4 76 3.6E-26 T 23-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A3L08_03265 7a9fb3a4e94db5d9b1bd2dc402042dc4 80 Gene3D G3DSA:3.30.1280.10 1 80 1.1E-27 T 23-10-2018 IPR036604 Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A3L08_03265 7a9fb3a4e94db5d9b1bd2dc402042dc4 80 TIGRFAM TIGR00302 TIGR00302: phosphoribosylformylglycinamidine synthase, purS protein 4 77 9.6E-25 T 23-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A3L08_03265 7a9fb3a4e94db5d9b1bd2dc402042dc4 80 ProDom PD010362 PHOSPHORIBOSYLFORMYLGLYCINAMIDINE PURS SYNTHETASE SYNTHASE COMPONENT SYNTHASE LIGASE FGAM UPF0062 I 10 80 5.0E-22 T 23-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A3L08_03265 7a9fb3a4e94db5d9b1bd2dc402042dc4 80 Hamap MF_01926 Phosphoribosylformylglycinamidine synthase subunit PurS [purS]. 3 76 20.524 T 23-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A3L08_03265 7a9fb3a4e94db5d9b1bd2dc402042dc4 80 SUPERFAMILY SSF82697 3 78 1.24E-24 T 23-10-2018 IPR036604 Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A3L08_07220 6dffa210feae803660f5deef138cfe3d 357 SUPERFAMILY SSF53137 131 259 1.57E-33 T 23-10-2018 A3L08_07220 6dffa210feae803660f5deef138cfe3d 357 Pfam PF03463 eRF1 domain 1 1 127 8.6E-29 T 23-10-2018 IPR005140 eRF1 domain 1/Pelota-like A3L08_07220 6dffa210feae803660f5deef138cfe3d 357 Gene3D G3DSA:2.30.30.870 1 129 3.1E-38 T 23-10-2018 IPR038069 Pelota/DOM34, N-terminal domain A3L08_07220 6dffa210feae803660f5deef138cfe3d 357 SUPERFAMILY SSF55315 251 356 2.87E-29 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like A3L08_07220 6dffa210feae803660f5deef138cfe3d 357 Hamap MF_01853 Protein pelota homolog [pelA]. 2 356 37.182 T 23-10-2018 IPR023521 Translation release factor pelota, archaea GO:0070481|GO:0070966|GO:0071025 A3L08_07220 6dffa210feae803660f5deef138cfe3d 357 Pfam PF03465 eRF1 domain 3 261 356 2.2E-25 T 23-10-2018 IPR005142 eRF1 domain 3 A3L08_07220 6dffa210feae803660f5deef138cfe3d 357 Pfam PF03464 eRF1 domain 2 136 252 2.9E-18 T 23-10-2018 IPR005141 eRF1 domain 2 A3L08_07220 6dffa210feae803660f5deef138cfe3d 357 TIGRFAM TIGR00111 pelota: mRNA surveillance protein pelota 1 356 2.9E-112 T 23-10-2018 IPR004405 Translation release factor pelota GO:0070481|GO:0070966|GO:0071025 A3L08_07220 6dffa210feae803660f5deef138cfe3d 357 SMART SM01194 1 129 3.6E-48 T 23-10-2018 IPR005140 eRF1 domain 1/Pelota-like A3L08_07220 6dffa210feae803660f5deef138cfe3d 357 Gene3D G3DSA:3.30.1330.30 258 357 5.6E-33 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like A3L08_07220 6dffa210feae803660f5deef138cfe3d 357 Gene3D G3DSA:3.30.420.60 133 257 1.4E-37 T 23-10-2018 A3L08_07220 6dffa210feae803660f5deef138cfe3d 357 SUPERFAMILY SSF159065 1 129 7.72E-36 T 23-10-2018 IPR038069 Pelota/DOM34, N-terminal domain A3L08_05675 f36f828fe55ac4430df982b23210ccf3 501 Gene3D G3DSA:1.10.10.10 1 111 5.7E-6 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L08_05675 f36f828fe55ac4430df982b23210ccf3 501 SUPERFAMILY SSF46785 70 142 5.56E-5 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L08_05675 f36f828fe55ac4430df982b23210ccf3 501 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 189 497 2.6E-95 T 23-10-2018 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 A3L08_05675 f36f828fe55ac4430df982b23210ccf3 501 SUPERFAMILY SSF46785 2 70 9.35E-5 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L08_05675 f36f828fe55ac4430df982b23210ccf3 501 Hamap MF_00282 Phenylalanine--tRNA ligase alpha subunit [pheS]. 2 498 38.265 T 23-10-2018 IPR022917 Phenylalanine-tRNA ligase alpha subunit, bacterial/archaeal GO:0004826 KEGG: 00970+6.1.1.20 A3L08_05675 f36f828fe55ac4430df982b23210ccf3 501 SUPERFAMILY SSF55681 224 497 2.95E-59 T 23-10-2018 A3L08_05675 f36f828fe55ac4430df982b23210ccf3 501 Pfam PF01409 tRNA synthetases class II core domain (F) 224 496 3.6E-82 T 23-10-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 A3L08_05675 f36f828fe55ac4430df982b23210ccf3 501 Gene3D G3DSA:3.30.930.10 194 500 1.1E-89 T 23-10-2018 A3L08_05060 f64a8c6094d8dcc91932544bb04145ea 147 SUPERFAMILY SSF50249 23 147 4.88E-37 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L08_05060 f64a8c6094d8dcc91932544bb04145ea 147 PRINTS PR01034 Ribosomal protein S12 signature 47 62 9.7E-5 T 23-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L08_05060 f64a8c6094d8dcc91932544bb04145ea 147 PRINTS PR01034 Ribosomal protein S12 signature 79 98 9.7E-5 T 23-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L08_05060 f64a8c6094d8dcc91932544bb04145ea 147 PRINTS PR01034 Ribosomal protein S12 signature 62 77 9.7E-5 T 23-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L08_05060 f64a8c6094d8dcc91932544bb04145ea 147 PIRSF PIRSF002133 19 147 2.0E-37 T 23-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L08_05060 f64a8c6094d8dcc91932544bb04145ea 147 TIGRFAM TIGR00982 uS12_E_A: ribosomal protein uS12 9 147 1.1E-81 T 23-10-2018 IPR005680 Ribosomal protein S23, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_05060 f64a8c6094d8dcc91932544bb04145ea 147 Pfam PF00164 Ribosomal protein S12/S23 32 146 7.5E-51 T 23-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L08_05060 f64a8c6094d8dcc91932544bb04145ea 147 Hamap MF_00403_A 30S ribosomal protein S12 [rpsL]. 1 147 45.158 T 23-10-2018 IPR022863 Ribosomal protein S12, archaea A3L08_05060 f64a8c6094d8dcc91932544bb04145ea 147 Gene3D G3DSA:2.40.50.140 28 147 1.1E-51 T 23-10-2018 A3L08_05060 f64a8c6094d8dcc91932544bb04145ea 147 ProSitePatterns PS00055 Ribosomal protein S12 signature. 63 70 - T 23-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L08_09745 eddcbe73797ddef0a3a5f7732939d453 220 Hamap MF_00090 Protein-L-isoaspartate O-methyltransferase [pcm]. 3 218 41.591 T 23-10-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 A3L08_09745 eddcbe73797ddef0a3a5f7732939d453 220 ProSitePatterns PS01279 Protein-L-isoaspartate(D-aspartate) O-methyltransferase signature. 137 152 - T 23-10-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 A3L08_09745 eddcbe73797ddef0a3a5f7732939d453 220 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 12 215 6.6E-68 T 23-10-2018 A3L08_09745 eddcbe73797ddef0a3a5f7732939d453 220 Gene3D G3DSA:3.40.50.150 1 220 4.9E-96 T 23-10-2018 A3L08_09745 eddcbe73797ddef0a3a5f7732939d453 220 TIGRFAM TIGR00080 pimt: protein-L-isoaspartate O-methyltransferase 12 215 3.6E-64 T 23-10-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 A3L08_09745 eddcbe73797ddef0a3a5f7732939d453 220 SUPERFAMILY SSF53335 6 215 7.9E-54 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L08_04100 9d4515b9cb629efded3a6864ab304d5c 141 Pfam PF00238 Ribosomal protein L14p/L23e 23 140 1.0E-34 T 23-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 A3L08_04100 9d4515b9cb629efded3a6864ab304d5c 141 SUPERFAMILY SSF50193 16 141 2.88E-44 T 23-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 A3L08_04100 9d4515b9cb629efded3a6864ab304d5c 141 TIGRFAM TIGR03673 uL14_arch: 50S ribosomal protein uL14 15 140 1.6E-60 T 23-10-2018 IPR019971 Ribosomal protein L14P, archaeal A3L08_04100 9d4515b9cb629efded3a6864ab304d5c 141 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 20 141 19.396 T 23-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 A3L08_04100 9d4515b9cb629efded3a6864ab304d5c 141 SMART SM01374 20 141 6.3E-57 T 23-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 A3L08_04100 9d4515b9cb629efded3a6864ab304d5c 141 Gene3D G3DSA:2.40.150.20 1 140 3.8E-49 T 23-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 A3L08_07865 58555c6ad7a8e1c42cb72c5bcf2fc9f9 473 Pfam PF01523 Putative modulator of DNA gyrase 19 325 9.0E-59 T 23-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 A3L08_07865 58555c6ad7a8e1c42cb72c5bcf2fc9f9 473 SUPERFAMILY SSF111283 1 468 4.58E-105 T 23-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 A3L08_07865 58555c6ad7a8e1c42cb72c5bcf2fc9f9 473 Gene3D G3DSA:3.30.2290.10 1 195 4.2E-26 T 23-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal A3L08_07865 58555c6ad7a8e1c42cb72c5bcf2fc9f9 473 PIRSF PIRSF004919 1 472 6.9E-154 T 23-10-2018 IPR025502 TldD A3L08_05600 093978a9fabc1573919d8e89645b6462 128 Gene3D G3DSA:1.10.1520.20 2 128 2.4E-45 T 23-10-2018 IPR038133 Ribonuclease III superfamily, archaeal A3L08_05600 093978a9fabc1573919d8e89645b6462 128 SUPERFAMILY SSF69065 7 127 1.57E-47 T 23-10-2018 IPR036389 Ribonuclease III, endonuclease domain superfamily GO:0004525|GO:0006396 A3L08_05600 093978a9fabc1573919d8e89645b6462 128 Pfam PF11469 Ribonuclease III 10 127 3.2E-56 T 23-10-2018 IPR021568 Ribonuclease III, archaeal A3L08_05385 5e60455464479fb894a0c580ba019d2d 442 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 304 7.8E-57 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A3L08_05385 5e60455464479fb894a0c580ba019d2d 442 Gene3D G3DSA:3.50.50.60 6 315 1.5E-112 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L08_05385 5e60455464479fb894a0c580ba019d2d 442 SUPERFAMILY SSF55424 321 439 2.23E-29 T 23-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 A3L08_05385 5e60455464479fb894a0c580ba019d2d 442 Gene3D G3DSA:3.50.50.60 44 242 1.5E-112 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L08_05385 5e60455464479fb894a0c580ba019d2d 442 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 150 175 1.3E-21 T 23-10-2018 A3L08_05385 5e60455464479fb894a0c580ba019d2d 442 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 234 248 1.3E-21 T 23-10-2018 A3L08_05385 5e60455464479fb894a0c580ba019d2d 442 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 275 282 1.3E-21 T 23-10-2018 A3L08_05385 5e60455464479fb894a0c580ba019d2d 442 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 1.3E-21 T 23-10-2018 A3L08_05385 5e60455464479fb894a0c580ba019d2d 442 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 385 400 1.3E-21 T 23-10-2018 A3L08_05385 5e60455464479fb894a0c580ba019d2d 442 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 233 249 5.9E-27 T 23-10-2018 A3L08_05385 5e60455464479fb894a0c580ba019d2d 442 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 103 121 5.9E-27 T 23-10-2018 A3L08_05385 5e60455464479fb894a0c580ba019d2d 442 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 260 282 5.9E-27 T 23-10-2018 A3L08_05385 5e60455464479fb894a0c580ba019d2d 442 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 5.9E-27 T 23-10-2018 A3L08_05385 5e60455464479fb894a0c580ba019d2d 442 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 150 168 5.9E-27 T 23-10-2018 A3L08_05385 5e60455464479fb894a0c580ba019d2d 442 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 327 428 1.9E-18 T 23-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 A3L08_05385 5e60455464479fb894a0c580ba019d2d 442 TIGRFAM TIGR03385 CoA_CoA_reduc: CoA-disulfide reductase 6 437 2.4E-181 T 23-10-2018 IPR017758 Coenzyme A disulphide reductase GO:0003756|GO:0050451|GO:0050660|GO:0050661|GO:0055114 A3L08_05385 5e60455464479fb894a0c580ba019d2d 442 Gene3D G3DSA:3.50.50.60 321 442 2.1E-44 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L08_05385 5e60455464479fb894a0c580ba019d2d 442 SUPERFAMILY SSF51905 1 345 1.8E-50 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L08_02360 fbb294c0f617da137f87aef115163752 75 SUPERFAMILY SSF47598 7 49 1.1E-6 T 23-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 A3L08_06410 d12dd8223a88583cf018902f94510fc2 149 SMART SM00344 5 111 4.8E-21 T 23-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A3L08_06410 d12dd8223a88583cf018902f94510fc2 149 SUPERFAMILY SSF54909 67 146 6.26E-6 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel A3L08_06410 d12dd8223a88583cf018902f94510fc2 149 Gene3D G3DSA:1.10.10.10 1 56 9.8E-20 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L08_06410 d12dd8223a88583cf018902f94510fc2 149 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 5 21 1.2E-10 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L08_06410 d12dd8223a88583cf018902f94510fc2 149 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 32 51 1.2E-10 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L08_06410 d12dd8223a88583cf018902f94510fc2 149 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 21 32 1.2E-10 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L08_06410 d12dd8223a88583cf018902f94510fc2 149 SUPERFAMILY SSF46785 5 65 4.68E-14 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L08_06410 d12dd8223a88583cf018902f94510fc2 149 Pfam PF13412 Winged helix-turn-helix DNA-binding 7 52 3.8E-15 T 23-10-2018 A3L08_06410 d12dd8223a88583cf018902f94510fc2 149 Gene3D G3DSA:3.30.70.920 57 149 2.8E-28 T 23-10-2018 A3L08_06410 d12dd8223a88583cf018902f94510fc2 149 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 20 36 8.7E-5 T 23-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 A3L08_06410 d12dd8223a88583cf018902f94510fc2 149 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 36 51 8.7E-5 T 23-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 A3L08_03070 c5fe47cfc65c4345f444a7ce9e690c7d 478 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 30 384 5.6E-26 T 23-10-2018 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 A3L08_03070 c5fe47cfc65c4345f444a7ce9e690c7d 478 Gene3D G3DSA:3.40.720.10 364 451 1.8E-8 T 23-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 A3L08_03070 c5fe47cfc65c4345f444a7ce9e690c7d 478 Gene3D G3DSA:3.40.720.10 1 257 3.7E-32 T 23-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 A3L08_03070 c5fe47cfc65c4345f444a7ce9e690c7d 478 SUPERFAMILY SSF53649 3 420 7.56E-34 T 23-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 A3L08_05345 f8faf75e0bad0c2ae780ca6b44b68030 369 Gene3D G3DSA:3.40.50.11750 17 262 6.7E-111 T 23-10-2018 A3L08_05345 f8faf75e0bad0c2ae780ca6b44b68030 369 Pfam PF01924 Hydrogenase formation hypA family 12 366 1.1E-135 T 23-10-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 A3L08_05345 f8faf75e0bad0c2ae780ca6b44b68030 369 PIRSF PIRSF005622 1 369 3.9E-144 T 23-10-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 A3L08_05345 f8faf75e0bad0c2ae780ca6b44b68030 369 Gene3D G3DSA:1.10.10.2140 317 369 1.2E-25 T 23-10-2018 A3L08_05345 f8faf75e0bad0c2ae780ca6b44b68030 369 TIGRFAM TIGR00075 hypD: hydrogenase expression/formation protein HypD 6 366 1.8E-134 T 23-10-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 A3L08_05345 f8faf75e0bad0c2ae780ca6b44b68030 369 Gene3D G3DSA:3.40.50.11740 61 302 6.7E-111 T 23-10-2018 A3L08_02310 c3d8b456b29b78b7469c65bf5ec029bf 427 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 318 412 1.4E-23 T 23-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A3L08_02310 c3d8b456b29b78b7469c65bf5ec029bf 427 PIRSF PIRSF500134 1 423 8.5E-145 T 23-10-2018 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346|MetaCyc: PWY-7820 A3L08_02310 c3d8b456b29b78b7469c65bf5ec029bf 427 Gene3D G3DSA:3.40.50.720 1 216 1.0E-79 T 23-10-2018 A3L08_02310 c3d8b456b29b78b7469c65bf5ec029bf 427 SMART SM00984 317 415 1.4E-36 T 23-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A3L08_02310 c3d8b456b29b78b7469c65bf5ec029bf 427 SUPERFAMILY SSF48179 202 296 2.38E-32 T 23-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 A3L08_02310 c3d8b456b29b78b7469c65bf5ec029bf 427 SUPERFAMILY SSF51735 1 194 1.88E-55 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L08_02310 c3d8b456b29b78b7469c65bf5ec029bf 427 PIRSF PIRSF000124 1 427 7.6E-140 T 23-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 A3L08_02310 c3d8b456b29b78b7469c65bf5ec029bf 427 SUPERFAMILY SSF52413 303 417 3.27E-30 T 23-10-2018 IPR036220 UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily Reactome: R-HSA-173599 A3L08_02310 c3d8b456b29b78b7469c65bf5ec029bf 427 Gene3D G3DSA:3.40.50.720 217 427 7.8E-76 T 23-10-2018 A3L08_02310 c3d8b456b29b78b7469c65bf5ec029bf 427 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 1 409 4.5E-143 T 23-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 A3L08_02310 c3d8b456b29b78b7469c65bf5ec029bf 427 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 1 188 5.0E-66 T 23-10-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A3L08_02310 c3d8b456b29b78b7469c65bf5ec029bf 427 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 202 294 1.7E-38 T 23-10-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A3L08_09090 e80b15256c6869cd1d56f451856d5e96 256 Gene3D G3DSA:3.30.540.10 2 139 1.6E-34 T 23-10-2018 A3L08_09090 e80b15256c6869cd1d56f451856d5e96 256 Gene3D G3DSA:3.40.190.80 145 254 7.3E-28 T 23-10-2018 A3L08_09090 e80b15256c6869cd1d56f451856d5e96 256 Pfam PF00459 Inositol monophosphatase family 7 251 4.3E-35 T 23-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A3L08_09090 e80b15256c6869cd1d56f451856d5e96 256 SUPERFAMILY SSF56655 7 248 2.09E-54 T 23-10-2018 A3L08_09090 e80b15256c6869cd1d56f451856d5e96 256 PRINTS PR00377 Inositol monophosphatase superfamily signature 40 60 1.9E-26 T 23-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A3L08_09090 e80b15256c6869cd1d56f451856d5e96 256 PRINTS PR00377 Inositol monophosphatase superfamily signature 164 185 1.9E-26 T 23-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A3L08_09090 e80b15256c6869cd1d56f451856d5e96 256 PRINTS PR00377 Inositol monophosphatase superfamily signature 197 221 1.9E-26 T 23-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A3L08_09090 e80b15256c6869cd1d56f451856d5e96 256 PRINTS PR00377 Inositol monophosphatase superfamily signature 129 152 1.9E-26 T 23-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A3L08_09090 e80b15256c6869cd1d56f451856d5e96 256 PRINTS PR00377 Inositol monophosphatase superfamily signature 80 96 1.9E-26 T 23-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A3L08_01175 d229132bdf25efb572a61be1c91f8c2d 162 Pfam PF02915 Rubrerythrin 23 143 2.9E-8 T 23-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 A3L08_01175 d229132bdf25efb572a61be1c91f8c2d 162 SUPERFAMILY SSF47240 22 159 1.01E-16 T 23-10-2018 IPR009078 Ferritin-like superfamily A3L08_01175 d229132bdf25efb572a61be1c91f8c2d 162 Gene3D G3DSA:1.20.1260.10 15 160 1.1E-22 T 23-10-2018 IPR012347 Ferritin-like A3L08_06870 3758b021e286f545120983955fc71c46 357 Gene3D G3DSA:3.10.50.80 3 165 4.5E-52 T 23-10-2018 A3L08_06870 3758b021e286f545120983955fc71c46 357 SUPERFAMILY SSF54534 3 156 1.06E-42 T 23-10-2018 A3L08_06870 3758b021e286f545120983955fc71c46 357 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 3 154 1.1E-17 T 23-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain A3L08_05320 b38592a0129bf9f50d215dbb34f4371c 161 Pfam PF01750 Hydrogenase maturation protease 31 151 4.3E-16 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 A3L08_05320 b38592a0129bf9f50d215dbb34f4371c 161 PRINTS PR00446 Hydrogen uptake protein signature 45 62 2.6E-8 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 A3L08_05320 b38592a0129bf9f50d215dbb34f4371c 161 PRINTS PR00446 Hydrogen uptake protein signature 26 37 2.6E-8 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 A3L08_05320 b38592a0129bf9f50d215dbb34f4371c 161 PRINTS PR00446 Hydrogen uptake protein signature 68 78 2.6E-8 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 A3L08_05320 b38592a0129bf9f50d215dbb34f4371c 161 PRINTS PR00446 Hydrogen uptake protein signature 14 26 2.6E-8 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 A3L08_05320 b38592a0129bf9f50d215dbb34f4371c 161 TIGRFAM TIGR00072 hydrog_prot: hydrogenase maturation protease 15 152 8.3E-32 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 A3L08_05320 b38592a0129bf9f50d215dbb34f4371c 161 SUPERFAMILY SSF53163 12 157 1.03E-30 T 23-10-2018 IPR023430 Peptidase HybD-like domain superfamily A3L08_05320 b38592a0129bf9f50d215dbb34f4371c 161 Gene3D G3DSA:3.40.50.1450 10 160 3.5E-42 T 23-10-2018 IPR023430 Peptidase HybD-like domain superfamily A3L08_05810 afc6be01a7d78a23f8a2bc9fe4fc7c21 164 SMART SM00116 105 152 0.0017 T 23-10-2018 IPR000644 CBS domain A3L08_05810 afc6be01a7d78a23f8a2bc9fe4fc7c21 164 SMART SM00116 24 72 3.9 T 23-10-2018 IPR000644 CBS domain A3L08_05810 afc6be01a7d78a23f8a2bc9fe4fc7c21 164 Gene3D G3DSA:3.10.580.10 1 73 6.1E-5 T 23-10-2018 A3L08_05810 afc6be01a7d78a23f8a2bc9fe4fc7c21 164 Gene3D G3DSA:3.10.580.10 77 156 2.0E-10 T 23-10-2018 A3L08_05810 afc6be01a7d78a23f8a2bc9fe4fc7c21 164 Pfam PF00571 CBS domain 99 150 3.9E-7 T 23-10-2018 IPR000644 CBS domain A3L08_05810 afc6be01a7d78a23f8a2bc9fe4fc7c21 164 Pfam PF00571 CBS domain 24 71 7.6E-4 T 23-10-2018 IPR000644 CBS domain A3L08_05810 afc6be01a7d78a23f8a2bc9fe4fc7c21 164 SUPERFAMILY SSF54631 6 152 2.74E-19 T 23-10-2018 A3L08_07160 4b38b905eaa9c636ce34107653be7ffb 245 Pfam PF01925 Sulfite exporter TauE/SafE 8 240 1.9E-37 T 23-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 A3L08_07520 1160fa5a14d43e9252040bc495eb250b 284 Gene3D G3DSA:3.20.20.60 2 272 4.0E-108 T 23-10-2018 A3L08_07520 1160fa5a14d43e9252040bc495eb250b 284 TIGRFAM TIGR00222 panB: 3-methyl-2-oxobutanoate hydroxymethyltransferase 3 262 3.6E-88 T 23-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 A3L08_07520 1160fa5a14d43e9252040bc495eb250b 284 Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. 4 262 40.691 T 23-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 A3L08_07520 1160fa5a14d43e9252040bc495eb250b 284 Pfam PF02548 Ketopantoate hydroxymethyltransferase 4 257 5.7E-105 T 23-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 A3L08_07520 1160fa5a14d43e9252040bc495eb250b 284 SUPERFAMILY SSF51621 4 262 8.24E-101 T 23-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 A3L08_07520 1160fa5a14d43e9252040bc495eb250b 284 PIRSF PIRSF000388 1 265 1.6E-102 T 23-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 A3L08_04770 1d9336ac83ad1e14cb54065ae8191ee6 199 Hamap MF_01078 UPF0278 protein . 1 193 29.921 T 23-10-2018 IPR014856 PIN-domain ribonuclease A3L08_04770 1d9336ac83ad1e14cb54065ae8191ee6 199 SUPERFAMILY SSF88723 71 184 2.69E-7 T 23-10-2018 IPR029060 PIN-like domain superfamily A3L08_04770 1d9336ac83ad1e14cb54065ae8191ee6 199 TIGRFAM TIGR03875 RNA_lig_partner: RNA ligase partner, MJ_0950 family 2 189 1.4E-70 T 23-10-2018 IPR014856 PIN-domain ribonuclease A3L08_04770 1d9336ac83ad1e14cb54065ae8191ee6 199 Pfam PF08745 PINc domain ribonuclease 2 189 8.8E-66 T 23-10-2018 IPR014856 PIN-domain ribonuclease A3L08_01210 131923d687ee71b5f9f92fbd6cad8460 183 Gene3D G3DSA:3.40.50.620 42 183 8.6E-8 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L08_01210 131923d687ee71b5f9f92fbd6cad8460 183 Pfam PF00582 Universal stress protein family 69 182 1.0E-4 T 23-10-2018 IPR006016 UspA A3L08_01210 131923d687ee71b5f9f92fbd6cad8460 183 SUPERFAMILY SSF52402 64 182 1.67E-8 T 23-10-2018 A3L08_01460 58aedff1cba09f26141d9924d6edd42c 652 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 267 576 4.3E-18 T 23-10-2018 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 A3L08_01460 58aedff1cba09f26141d9924d6edd42c 652 Gene3D G3DSA:3.60.9.10 2 228 3.7E-24 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily A3L08_01460 58aedff1cba09f26141d9924d6edd42c 652 SMART SM00790 1 226 4.7E-71 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 A3L08_01460 58aedff1cba09f26141d9924d6edd42c 652 SUPERFAMILY SSF48310 241 650 6.28E-67 T 23-10-2018 IPR036021 Aldehyde ferredoxin oxidoreductase-like, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 A3L08_01460 58aedff1cba09f26141d9924d6edd42c 652 SUPERFAMILY SSF56228 3 228 1.96E-44 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily A3L08_01460 58aedff1cba09f26141d9924d6edd42c 652 Gene3D G3DSA:1.10.569.10 280 474 4.0E-13 T 23-10-2018 IPR013984 Aldehyde ferredoxin oxidoreductase, domain 2 A3L08_01460 58aedff1cba09f26141d9924d6edd42c 652 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 4 225 3.9E-41 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 A3L08_05125 ec711ea7fb10b5472561646567741111 193 Pfam PF03956 Lysine exporter LysO 9 190 1.1E-57 T 23-10-2018 IPR005642 Lysine exporter LysO A3L08_05125 ec711ea7fb10b5472561646567741111 193 ProDom PD022789 MEMBRANE SURFACE PRECURSOR SIGNAL PROTEIN YBJE TRANSMEMBRANE INNER PREDICTED STY0934 24 193 8.0E-47 T 23-10-2018 IPR005642 Lysine exporter LysO A3L08_08150 99aa11604358f583b020e98bd1a11b7c 361 Pfam PF03065 Glycosyl hydrolase family 57 3 313 1.9E-50 T 23-10-2018 IPR004300 Glycoside hydrolase family 57, N-terminal domain GO:0003824|GO:0005975 A3L08_08150 99aa11604358f583b020e98bd1a11b7c 361 SUPERFAMILY SSF88713 3 307 3.25E-44 T 23-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 A3L08_08150 99aa11604358f583b020e98bd1a11b7c 361 Gene3D G3DSA:3.20.110.20 3 182 8.9E-27 T 23-10-2018 A3L08_04455 b68f1d8c4abe9d0c4113ca3ee6180ee8 194 Hamap MF_00256 50S ribosomal protein L15e [rpl15e]. 1 193 43.408 T 23-10-2018 IPR020926 Ribosomal protein L15e, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L08_04455 b68f1d8c4abe9d0c4113ca3ee6180ee8 194 SUPERFAMILY SSF54189 1 192 5.76E-88 T 23-10-2018 IPR012678 Ribosomal protein L23/L15e core domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L08_04455 b68f1d8c4abe9d0c4113ca3ee6180ee8 194 SMART SM01384 2 191 4.3E-135 T 23-10-2018 IPR000439 Ribosomal protein L15e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_04455 b68f1d8c4abe9d0c4113ca3ee6180ee8 194 Gene3D G3DSA:3.40.1120.10 1 193 1.9E-90 T 23-10-2018 IPR024794 Ribosomal protein L15e core domain superfamily GO:0003735|GO:0005840 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_04455 b68f1d8c4abe9d0c4113ca3ee6180ee8 194 Pfam PF00827 Ribosomal L15 2 189 2.9E-90 T 23-10-2018 IPR000439 Ribosomal protein L15e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_04455 b68f1d8c4abe9d0c4113ca3ee6180ee8 194 ProSitePatterns PS01194 Ribosomal protein L15e signature. 46 69 - T 23-10-2018 IPR020925 Ribosomal protein L15e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_04540 ea7577813def12998a7bbe880644b3a0 648 Pfam PF16661 Metallo-beta-lactamase superfamily domain 205 351 8.2E-9 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L08_04540 ea7577813def12998a7bbe880644b3a0 648 SUPERFAMILY SSF56281 183 647 4.29E-132 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L08_04540 ea7577813def12998a7bbe880644b3a0 648 SMART SM01027 433 557 6.6E-55 T 23-10-2018 IPR022712 Beta-Casp domain A3L08_04540 ea7577813def12998a7bbe880644b3a0 648 Pfam PF17214 KH domain 9 76 7.0E-27 T 23-10-2018 IPR033769 KH domain, archaeal A3L08_04540 ea7577813def12998a7bbe880644b3a0 648 Gene3D G3DSA:3.40.50.10890 401 588 1.3E-164 T 23-10-2018 A3L08_04540 ea7577813def12998a7bbe880644b3a0 648 SMART SM00849 198 428 7.8E-26 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L08_04540 ea7577813def12998a7bbe880644b3a0 648 Gene3D G3DSA:3.30.300.20 72 142 3.8E-64 T 23-10-2018 IPR015946 K homology domain-like, alpha/beta A3L08_04540 ea7577813def12998a7bbe880644b3a0 648 SUPERFAMILY SSF54814 96 141 2.22E-5 T 23-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 A3L08_04540 ea7577813def12998a7bbe880644b3a0 648 Gene3D G3DSA:3.60.15.10 191 627 1.3E-164 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L08_04540 ea7577813def12998a7bbe880644b3a0 648 Pfam PF10996 Beta-Casp domain 433 556 3.2E-24 T 23-10-2018 IPR022712 Beta-Casp domain A3L08_04540 ea7577813def12998a7bbe880644b3a0 648 SMART SM00322 102 169 4.2E-5 T 23-10-2018 IPR004087 K Homology domain GO:0003676 A3L08_04540 ea7577813def12998a7bbe880644b3a0 648 TIGRFAM TIGR03675 arCOG00543: arCOG00543 universal archaeal KH-domain/beta-lactamase-domain protein 13 647 2.3E-298 T 23-10-2018 IPR019975 KH-domain/beta-lactamase-domain protein, archaea A3L08_04540 ea7577813def12998a7bbe880644b3a0 648 Gene3D G3DSA:3.30.300.230 17 176 3.8E-64 T 23-10-2018 A3L08_04540 ea7577813def12998a7bbe880644b3a0 648 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 576 639 5.2E-17 T 23-10-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain A3L08_03215 2f05f01b901e342ee218d26fd82b7d53 335 ProSitePatterns PS01235 PdxS/SNZ family signature. 248 266 - T 23-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A3L08_03215 2f05f01b901e342ee218d26fd82b7d53 335 Pfam PF05690 Thiazole biosynthesis protein ThiG 245 299 4.7E-8 T 23-10-2018 IPR033983 Thiazole synthase ThiG KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 A3L08_03215 2f05f01b901e342ee218d26fd82b7d53 335 PIRSF PIRSF029271 3 335 1.1E-146 T 23-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A3L08_03215 2f05f01b901e342ee218d26fd82b7d53 335 Hamap MF_01824 Pyridoxal 5'-phosphate synthase subunit PdxS [pdxS]. 10 335 52.846 T 23-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A3L08_03215 2f05f01b901e342ee218d26fd82b7d53 335 Gene3D G3DSA:3.20.20.70 1 316 2.0E-152 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L08_03215 2f05f01b901e342ee218d26fd82b7d53 335 SUPERFAMILY SSF51366 24 310 4.33E-60 T 23-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 A3L08_03215 2f05f01b901e342ee218d26fd82b7d53 335 Pfam PF01680 SOR/SNZ family 13 213 2.1E-94 T 23-10-2018 IPR033755 PdxS/SNZ N-terminal domain KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A3L08_03215 2f05f01b901e342ee218d26fd82b7d53 335 TIGRFAM TIGR00343 TIGR00343: pyridoxal 5'-phosphate synthase, synthase subunit Pdx1 15 334 1.0E-144 T 23-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A3L08_00310 c55ffe6a6eb0d1de62745c96d668124a 114 Pfam PF01922 SRP19 protein 5 84 7.4E-13 T 23-10-2018 IPR002778 Signal recognition particle, SRP19 subunit GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 A3L08_00310 c55ffe6a6eb0d1de62745c96d668124a 114 Gene3D G3DSA:3.30.56.30 1 105 3.7E-30 T 23-10-2018 IPR036521 Signal recognition particle, subunit SRP19-like superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 A3L08_00310 c55ffe6a6eb0d1de62745c96d668124a 114 SUPERFAMILY SSF69695 2 107 5.62E-22 T 23-10-2018 IPR036521 Signal recognition particle, subunit SRP19-like superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 A3L08_07140 89335031df5b381fe0feb3ffd8c10270 334 SUPERFAMILY SSF51735 3 158 3.63E-47 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L08_07140 89335031df5b381fe0feb3ffd8c10270 334 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 3 108 7.5E-14 T 23-10-2018 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A3L08_07140 89335031df5b381fe0feb3ffd8c10270 334 SUPERFAMILY SSF55347 140 301 2.34E-51 T 23-10-2018 A3L08_07140 89335031df5b381fe0feb3ffd8c10270 334 Hamap MF_00559 Glyceraldehyde-3-phosphate dehydrogenase [gap]. 1 334 189.585 T 23-10-2018 IPR006436 Glyceraldehyde-3-phosphate dehydrogenase, type II GO:0005737|GO:0006096|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.59|KEGG: 00710+1.2.1.59 A3L08_07140 89335031df5b381fe0feb3ffd8c10270 334 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 146 296 4.4E-30 T 23-10-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L08_07140 89335031df5b381fe0feb3ffd8c10270 334 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 139 146 - T 23-10-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L08_07140 89335031df5b381fe0feb3ffd8c10270 334 SMART SM00846 3 141 8.1E-21 T 23-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L08_07140 89335031df5b381fe0feb3ffd8c10270 334 Gene3D G3DSA:3.40.50.720 3 331 3.2E-149 T 23-10-2018 A3L08_07140 89335031df5b381fe0feb3ffd8c10270 334 PIRSF PIRSF000149 1 318 1.3E-85 T 23-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L08_07140 89335031df5b381fe0feb3ffd8c10270 334 TIGRFAM TIGR01546 GAPDH-II_archae: glyceraldehyde-3-phosphate dehydrogenase, type II 5 333 2.9E-179 T 23-10-2018 IPR006436 Glyceraldehyde-3-phosphate dehydrogenase, type II GO:0005737|GO:0006096|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.59|KEGG: 00710+1.2.1.59 A3L08_07140 89335031df5b381fe0feb3ffd8c10270 334 Gene3D G3DSA:3.30.360.10 140 301 3.2E-149 T 23-10-2018 A3L08_06865 8a3681e897bb7414f77367cadf3a114f 476 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 3 474 39.593 T 23-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 A3L08_06865 8a3681e897bb7414f77367cadf3a114f 476 SMART SM00840 356 417 1.5E-15 T 23-10-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 A3L08_06865 8a3681e897bb7414f77367cadf3a114f 476 SUPERFAMILY SSF47323 316 473 1.92E-35 T 23-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L08_06865 8a3681e897bb7414f77367cadf3a114f 476 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 222 243 4.0E-30 T 23-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 A3L08_06865 8a3681e897bb7414f77367cadf3a114f 476 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 191 209 4.0E-30 T 23-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 A3L08_06865 8a3681e897bb7414f77367cadf3a114f 476 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 26 37 4.0E-30 T 23-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 A3L08_06865 8a3681e897bb7414f77367cadf3a114f 476 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 62 71 4.0E-30 T 23-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 A3L08_06865 8a3681e897bb7414f77367cadf3a114f 476 Gene3D G3DSA:1.20.120.640 306 473 2.7E-38 T 23-10-2018 A3L08_06865 8a3681e897bb7414f77367cadf3a114f 476 Pfam PF09190 DALR domain 356 415 2.6E-16 T 23-10-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 A3L08_06865 8a3681e897bb7414f77367cadf3a114f 476 SUPERFAMILY SSF52374 3 314 1.15E-110 T 23-10-2018 A3L08_06865 8a3681e897bb7414f77367cadf3a114f 476 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 3 473 2.1E-181 T 23-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 A3L08_06865 8a3681e897bb7414f77367cadf3a114f 476 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 16 314 6.9E-138 T 23-10-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 A3L08_06865 8a3681e897bb7414f77367cadf3a114f 476 Gene3D G3DSA:3.40.50.620 1 305 4.7E-149 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L08_04895 b8568c05c7ee1c387703456092754d29 235 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 9 68 5.7E-5 T 23-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L08_04895 b8568c05c7ee1c387703456092754d29 235 SUPERFAMILY SSF53738 9 76 1.06E-6 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L08_04895 b8568c05c7ee1c387703456092754d29 235 Gene3D G3DSA:3.40.120.10 3 78 1.2E-5 T 23-10-2018 A3L08_04895 b8568c05c7ee1c387703456092754d29 235 SUPERFAMILY SSF53738 128 207 4.06E-7 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L08_03625 b94d94ab0183e47f118c5026d19bb932 357 Gene3D G3DSA:2.40.50.140 166 315 8.2E-11 T 23-10-2018 A3L08_03625 b94d94ab0183e47f118c5026d19bb932 357 Pfam PF01336 OB-fold nucleic acid binding domain 73 151 6.2E-14 T 23-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 A3L08_03625 b94d94ab0183e47f118c5026d19bb932 357 Gene3D G3DSA:2.40.50.140 58 159 3.1E-22 T 23-10-2018 A3L08_03625 b94d94ab0183e47f118c5026d19bb932 357 SUPERFAMILY SSF50249 182 348 5.31E-15 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L08_03625 b94d94ab0183e47f118c5026d19bb932 357 SUPERFAMILY SSF50249 53 176 5.14E-28 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L08_03625 b94d94ab0183e47f118c5026d19bb932 357 Pfam PF08646 Replication factor-A C terminal domain 193 278 1.3E-9 T 23-10-2018 IPR013955 Replication factor A, C-terminal A3L08_09385 bfad197814c9761726beec2259de8e1d 343 Pfam PF00534 Glycosyl transferases group 1 174 309 6.3E-23 T 23-10-2018 IPR001296 Glycosyl transferase, family 1 A3L08_09385 bfad197814c9761726beec2259de8e1d 343 Gene3D G3DSA:3.40.50.2000 171 317 2.3E-29 T 23-10-2018 A3L08_09385 bfad197814c9761726beec2259de8e1d 343 SUPERFAMILY SSF53756 5 342 1.74E-72 T 23-10-2018 A3L08_09385 bfad197814c9761726beec2259de8e1d 343 Pfam PF13439 Glycosyltransferase Family 4 14 168 2.6E-30 T 23-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 A3L08_09385 bfad197814c9761726beec2259de8e1d 343 Gene3D G3DSA:3.40.50.2000 1 170 5.9E-40 T 23-10-2018 A3L08_04175 fa1d22bfb17c67f68708f7e3c4f93269 175 Pfam PF01956 Integral membrane protein DUF106 10 173 2.7E-31 T 23-10-2018 IPR002809 Integral membrane protein EMC3/TMCO1-like GO:0016020 A3L08_04175 fa1d22bfb17c67f68708f7e3c4f93269 175 SMART SM01415 10 174 1.8E-27 T 23-10-2018 IPR002809 Integral membrane protein EMC3/TMCO1-like GO:0016020 A3L08_01290 4c3d6ed3d71c54437cb44d3aa3447df1 119 SUPERFAMILY SSF69118 9 110 5.1E-27 T 23-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 A3L08_01290 4c3d6ed3d71c54437cb44d3aa3447df1 119 Pfam PF02627 Carboxymuconolactone decarboxylase family 30 107 1.7E-18 T 23-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 A3L08_01290 4c3d6ed3d71c54437cb44d3aa3447df1 119 Gene3D G3DSA:1.20.1290.10 2 114 1.2E-28 T 23-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 A3L08_01290 4c3d6ed3d71c54437cb44d3aa3447df1 119 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 43 86 5.3E-12 T 23-10-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 A3L08_03235 15be25bdb9b4243603e67d4a5ab37dce 239 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 4 233 32.608 T 23-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A3L08_03235 15be25bdb9b4243603e67d4a5ab37dce 239 Gene3D G3DSA:3.30.470.20 84 219 7.0E-96 T 23-10-2018 A3L08_03235 15be25bdb9b4243603e67d4a5ab37dce 239 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 3 214 1.6E-73 T 23-10-2018 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 A3L08_03235 15be25bdb9b4243603e67d4a5ab37dce 239 Gene3D G3DSA:3.30.200.20 21 230 7.0E-96 T 23-10-2018 A3L08_03235 15be25bdb9b4243603e67d4a5ab37dce 239 SUPERFAMILY SSF56104 7 234 1.11E-80 T 23-10-2018 A3L08_03235 15be25bdb9b4243603e67d4a5ab37dce 239 ProSitePatterns PS01057 SAICAR synthetase signature 1. 85 99 - T 23-10-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A3L08_03235 15be25bdb9b4243603e67d4a5ab37dce 239 Pfam PF01259 SAICAR synthetase 7 227 2.2E-67 T 23-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A3L08_03235 15be25bdb9b4243603e67d4a5ab37dce 239 ProSitePatterns PS01058 SAICAR synthetase signature 2. 171 179 - T 23-10-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A3L08_07535 daac5bbe3b66a6f46d7db9fe45e3e4e9 142 Gene3D G3DSA:3.55.10.10 1 142 6.2E-53 T 23-10-2018 IPR036820 Archease domain superfamily Reactome: R-HSA-6784531 A3L08_07535 daac5bbe3b66a6f46d7db9fe45e3e4e9 142 Pfam PF01951 Archease protein family (MTH1598/TM1083) 4 141 2.9E-45 T 23-10-2018 IPR023572 Archease domain Reactome: R-HSA-6784531 A3L08_07535 daac5bbe3b66a6f46d7db9fe45e3e4e9 142 ProDom PD012969 UPF0211 RIKEN CDNA ENRICHED MALE FULL-LENGTH LIBRARY ZBTB8OS ADULT C43H8.1 8 142 3.0E-35 T 23-10-2018 IPR023572 Archease domain Reactome: R-HSA-6784531 A3L08_07535 daac5bbe3b66a6f46d7db9fe45e3e4e9 142 SUPERFAMILY SSF69819 2 142 2.22E-48 T 23-10-2018 IPR036820 Archease domain superfamily Reactome: R-HSA-6784531 A3L08_07535 daac5bbe3b66a6f46d7db9fe45e3e4e9 142 Hamap MF_01222 Protein archease. 2 142 41.453 T 23-10-2018 IPR022952 Archease, archaea A3L08_03535 832c668fff2f98d721bfcf4ca8d93e47 328 Pfam PF00924 Mechanosensitive ion channel 106 305 8.6E-62 T 23-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 A3L08_03535 832c668fff2f98d721bfcf4ca8d93e47 328 Gene3D G3DSA:2.30.30.60 166 215 7.2E-14 T 23-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily A3L08_03535 832c668fff2f98d721bfcf4ca8d93e47 328 SUPERFAMILY SSF82689 219 315 1.7E-32 T 23-10-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 A3L08_03535 832c668fff2f98d721bfcf4ca8d93e47 328 SUPERFAMILY SSF82861 66 149 2.75E-8 T 23-10-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 A3L08_03535 832c668fff2f98d721bfcf4ca8d93e47 328 ProSitePatterns PS01246 Uncharacterized protein family UPF0003 signature. 180 214 - T 23-10-2018 IPR006686 Mechanosensitive ion channel MscS, conserved site GO:0016020 A3L08_03535 832c668fff2f98d721bfcf4ca8d93e47 328 SUPERFAMILY SSF50182 151 215 3.6E-18 T 23-10-2018 IPR010920 LSM domain superfamily A3L08_03535 832c668fff2f98d721bfcf4ca8d93e47 328 Gene3D G3DSA:3.30.70.100 217 309 3.3E-30 T 23-10-2018 A3L08_08700 b68d830437e9cf20e00b7e7797607459 316 Gene3D G3DSA:3.10.450.620 22 103 2.3E-5 T 23-10-2018 A3L08_08700 b68d830437e9cf20e00b7e7797607459 316 Pfam PF08843 Nucleotidyl transferase AbiEii toxin, Type IV TA system 37 275 2.7E-28 T 23-10-2018 IPR014942 Nucleotidyl transferase AbiEii toxin, Type IV TA system A3L08_04880 c635b124cc1eaea44ed9590089667436 830 Gene3D G3DSA:3.40.50.2000 270 406 3.1E-8 T 23-10-2018 A3L08_04880 c635b124cc1eaea44ed9590089667436 830 Pfam PF00343 Carbohydrate phosphorylase 273 612 4.1E-27 T 23-10-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 A3L08_04880 c635b124cc1eaea44ed9590089667436 830 Pfam PF00343 Carbohydrate phosphorylase 127 174 8.0E-5 T 23-10-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 A3L08_04880 c635b124cc1eaea44ed9590089667436 830 PIRSF PIRSF000460 2 768 5.5E-275 T 23-10-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 A3L08_04880 c635b124cc1eaea44ed9590089667436 830 ProSitePatterns PS00102 Phosphorylase pyridoxal-phosphate attachment site. 586 598 - T 23-10-2018 IPR035090 Phosphorylase pyridoxal-phosphate attachment site KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 A3L08_04880 c635b124cc1eaea44ed9590089667436 830 TIGRFAM TIGR02094 more_P_ylases: alpha-glucan phosphorylases 110 692 7.6E-256 T 23-10-2018 IPR011834 Alpha-glucan phosphorylase GO:0004645|GO:0005975|GO:0030170 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238 A3L08_04880 c635b124cc1eaea44ed9590089667436 830 Gene3D G3DSA:3.40.50.2000 117 185 7.9E-11 T 23-10-2018 A3L08_04880 c635b124cc1eaea44ed9590089667436 830 Pfam PF11897 Protein of unknown function (DUF3417) 16 123 6.9E-31 T 23-10-2018 IPR024517 Glycogen phosphorylase, domain of unknown function DUF3417 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238 A3L08_04880 c635b124cc1eaea44ed9590089667436 830 SUPERFAMILY SSF53756 16 726 1.61E-207 T 23-10-2018 A3L08_04880 c635b124cc1eaea44ed9590089667436 830 Gene3D G3DSA:3.40.50.2000 407 727 1.9E-44 T 23-10-2018 A3L08_05830 e1d48a6d59634faf675f25b32c1fc937 219 SUPERFAMILY SSF75217 1 215 3.45E-61 T 23-10-2018 IPR029028 Alpha/beta knot methyltransferases A3L08_05830 e1d48a6d59634faf675f25b32c1fc937 219 Hamap MF_00554 Ribosomal RNA small subunit methyltransferase Nep1 [nep1]. 2 216 39.664 T 23-10-2018 IPR023503 Ribosome biogenesis methyltransferase NEP1, archaea GO:0008168 A3L08_05830 e1d48a6d59634faf675f25b32c1fc937 219 Gene3D G3DSA:3.40.1280.10 1 218 4.0E-74 T 23-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal A3L08_05830 e1d48a6d59634faf675f25b32c1fc937 219 Pfam PF03587 EMG1/NEP1 methyltransferase 5 215 6.8E-49 T 23-10-2018 IPR005304 Ribosomal biogenesis, methyltransferase, EMG1/NEP1 GO:0008168 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 A3L08_01100 e2f259e85842d535e375e8155ec4777a 192 Gene3D G3DSA:3.40.50.300 1 189 1.0E-42 T 23-10-2018 A3L08_01100 e2f259e85842d535e375e8155ec4777a 192 SUPERFAMILY SSF52540 1 189 3.63E-19 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_01100 e2f259e85842d535e375e8155ec4777a 192 Pfam PF13238 AAA domain 3 138 1.7E-18 T 23-10-2018 A3L08_05285 13c58472b4469676488c1b83a9f15d4e 393 Pfam PF04055 Radical SAM superfamily 43 208 1.1E-16 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L08_05285 13c58472b4469676488c1b83a9f15d4e 393 PIRSF PIRSF037420 302 380 7.9E-7 T 23-10-2018 IPR017200 Coenzyme PQQ synthesis protein E A3L08_05285 13c58472b4469676488c1b83a9f15d4e 393 PIRSF PIRSF037420 33 237 6.0E-27 T 23-10-2018 IPR017200 Coenzyme PQQ synthesis protein E A3L08_05285 13c58472b4469676488c1b83a9f15d4e 393 Pfam PF13186 Iron-sulfur cluster-binding domain 270 348 3.2E-17 T 23-10-2018 IPR023885 4Fe4S-binding SPASM domain A3L08_05285 13c58472b4469676488c1b83a9f15d4e 393 SMART SM00729 39 252 2.1E-4 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A3L08_05285 13c58472b4469676488c1b83a9f15d4e 393 TIGRFAM TIGR04317 W_rSAM_matur: tungsten cofactor oxidoreducase radical SAM maturase 37 383 6.9E-152 T 23-10-2018 IPR027604 Tungsten cofactor oxidoreducase radical SAM maturase A3L08_05285 13c58472b4469676488c1b83a9f15d4e 393 SUPERFAMILY SSF102114 40 353 2.35E-59 T 23-10-2018 A3L08_05285 13c58472b4469676488c1b83a9f15d4e 393 Pfam PF13394 4Fe-4S single cluster domain 46 130 2.8E-7 T 23-10-2018 A3L08_06755 34927dccc60ce249d81414ea97a29abb 186 Gene3D G3DSA:3.40.920.10 1 185 3.2E-55 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 A3L08_06755 34927dccc60ce249d81414ea97a29abb 186 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 11 176 3.3E-35 T 23-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 A3L08_06755 34927dccc60ce249d81414ea97a29abb 186 SUPERFAMILY SSF53323 1 180 3.92E-41 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 A3L08_07225 fc7eca5616998a79f486d5747105fd17 332 SUPERFAMILY SSF56042 154 315 3.44E-27 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A3L08_07225 fc7eca5616998a79f486d5747105fd17 332 Pfam PF00586 AIR synthase related protein, N-terminal domain 45 144 1.1E-14 T 23-10-2018 IPR016188 PurM-like, N-terminal domain A3L08_07225 fc7eca5616998a79f486d5747105fd17 332 Pfam PF02769 AIR synthase related protein, C-terminal domain 155 306 1.7E-15 T 23-10-2018 IPR010918 PurM-like, C-terminal domain A3L08_07225 fc7eca5616998a79f486d5747105fd17 332 PIRSF PIRSF005644 1 330 2.8E-62 T 23-10-2018 IPR011854 Carbamoyl dehydratase HypE A3L08_07225 fc7eca5616998a79f486d5747105fd17 332 SUPERFAMILY SSF55326 7 148 3.49E-23 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A3L08_07225 fc7eca5616998a79f486d5747105fd17 332 Gene3D G3DSA:3.90.650.10 153 329 3.4E-31 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A3L08_07225 fc7eca5616998a79f486d5747105fd17 332 Gene3D G3DSA:3.30.1330.10 3 147 1.4E-24 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A3L08_06905 266e4107c354a36a4b3292400b040bfb 219 Gene3D G3DSA:3.30.200.20 4 86 1.7E-57 T 23-10-2018 A3L08_06905 266e4107c354a36a4b3292400b040bfb 219 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 1 219 19.186 T 23-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A3L08_06905 266e4107c354a36a4b3292400b040bfb 219 Pfam PF01259 SAICAR synthetase 4 203 1.4E-31 T 23-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A3L08_06905 266e4107c354a36a4b3292400b040bfb 219 Gene3D G3DSA:3.30.470.20 87 205 1.7E-57 T 23-10-2018 A3L08_06905 266e4107c354a36a4b3292400b040bfb 219 SUPERFAMILY SSF56104 1 205 6.87E-49 T 23-10-2018 A3L08_06905 266e4107c354a36a4b3292400b040bfb 219 ProSitePatterns PS01058 SAICAR synthetase signature 2. 175 183 - T 23-10-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A3L08_01365 03435c8539c944258aa9289c7c95ebbd 324 SMART SM00382 39 232 9.2E-16 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L08_01365 03435c8539c944258aa9289c7c95ebbd 324 Pfam PF13732 Domain of unknown function (DUF4162) 234 318 1.5E-7 T 23-10-2018 IPR025302 Domain of unknown function DUF4162 A3L08_01365 03435c8539c944258aa9289c7c95ebbd 324 Gene3D G3DSA:3.40.50.300 2 260 2.3E-66 T 23-10-2018 A3L08_01365 03435c8539c944258aa9289c7c95ebbd 324 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 27 319 1.1E-98 T 23-10-2018 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 A3L08_01365 03435c8539c944258aa9289c7c95ebbd 324 SUPERFAMILY SSF52540 4 235 6.84E-62 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_01365 03435c8539c944258aa9289c7c95ebbd 324 Pfam PF00005 ABC transporter 31 174 1.1E-29 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L08_01705 23b6776f325047aa4bc0d299a2c8b640 224 Pfam PF01865 Protein of unknown function DUF47 6 222 1.3E-45 T 23-10-2018 IPR018445 Putative phosphate transport regulator A3L08_01705 23b6776f325047aa4bc0d299a2c8b640 224 SUPERFAMILY SSF109755 25 221 9.1E-18 T 23-10-2018 A3L08_01705 23b6776f325047aa4bc0d299a2c8b640 224 Gene3D G3DSA:1.20.58.220 1 224 2.2E-49 T 23-10-2018 IPR038078 PhoU-like domain superfamily A3L08_01705 23b6776f325047aa4bc0d299a2c8b640 224 TIGRFAM TIGR00153 TIGR00153: TIGR00153 family protein 5 222 2.4E-35 T 23-10-2018 IPR002727 Protein of unknown function DUF47 A3L08_02090 c95a8879ad2c2f59a9488391001b87c2 480 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 204 479 21.49 T 23-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 A3L08_02090 c95a8879ad2c2f59a9488391001b87c2 480 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 211 474 2.9E-70 T 23-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 A3L08_02090 c95a8879ad2c2f59a9488391001b87c2 480 Hamap MF_01966 NAD(P)H-hydrate epimerase [nnrE]. 1 198 18.645 T 23-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 A3L08_02090 c95a8879ad2c2f59a9488391001b87c2 480 Pfam PF03853 YjeF-related protein N-terminus 22 182 2.4E-32 T 23-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 A3L08_02090 c95a8879ad2c2f59a9488391001b87c2 480 Gene3D G3DSA:3.40.1190.20 209 476 1.5E-73 T 23-10-2018 IPR029056 Ribokinase-like A3L08_02090 c95a8879ad2c2f59a9488391001b87c2 480 SUPERFAMILY SSF64153 4 225 5.23E-48 T 23-10-2018 IPR036652 YjeF N-terminal domain superfamily MetaCyc: PWY-6938 A3L08_02090 c95a8879ad2c2f59a9488391001b87c2 480 ProSitePatterns PS01050 YjeF C-terminal domain signature 2. 415 425 - T 23-10-2018 IPR017953 Carbohydrate kinase, predicted, conserved site A3L08_02090 c95a8879ad2c2f59a9488391001b87c2 480 PIRSF PIRSF017184 1 479 1.0E-96 T 23-10-2018 IPR030677 Bifunctional NAD(P)H-hydrate repair enzyme Nnr GO:0052855 MetaCyc: PWY-6938 A3L08_02090 c95a8879ad2c2f59a9488391001b87c2 480 Gene3D G3DSA:3.40.50.10260 9 202 1.3E-40 T 23-10-2018 IPR036652 YjeF N-terminal domain superfamily MetaCyc: PWY-6938 A3L08_02090 c95a8879ad2c2f59a9488391001b87c2 480 TIGRFAM TIGR00197 yjeF_nterm: YjeF family N-terminal domain 8 183 2.7E-42 T 23-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 A3L08_02090 c95a8879ad2c2f59a9488391001b87c2 480 Pfam PF01256 Carbohydrate kinase 227 471 1.9E-50 T 23-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 A3L08_02090 c95a8879ad2c2f59a9488391001b87c2 480 SUPERFAMILY SSF53613 212 473 2.12E-58 T 23-10-2018 IPR029056 Ribokinase-like A3L08_00905 411d257b5b621f4d9687396bdfaaf1f0 188 PIRSF PIRSF006503 1 188 4.8E-85 T 23-10-2018 IPR007162 Protein of unknown function DUF366 A3L08_00905 411d257b5b621f4d9687396bdfaaf1f0 188 Gene3D G3DSA:3.30.930.10 1 188 6.3E-73 T 23-10-2018 A3L08_00905 411d257b5b621f4d9687396bdfaaf1f0 188 Pfam PF04017 Domain of unknown function (DUF366) 5 185 3.6E-69 T 23-10-2018 IPR007162 Protein of unknown function DUF366 A3L08_00905 411d257b5b621f4d9687396bdfaaf1f0 188 SUPERFAMILY SSF55681 3 186 5.59E-72 T 23-10-2018 A3L08_00905 411d257b5b621f4d9687396bdfaaf1f0 188 ProDom PD022700 PH0223 5/5 GENOME PF0133 SEGMENT UNCHARACTERIZED MA4198 MJ0805 4 186 3.0E-93 T 23-10-2018 IPR007162 Protein of unknown function DUF366 A3L08_02250 180a0afe2eb5a63a187c80cab19fce03 202 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 160 172 5.1E-43 T 23-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 A3L08_02250 180a0afe2eb5a63a187c80cab19fce03 202 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 60 72 5.1E-43 T 23-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 A3L08_02250 180a0afe2eb5a63a187c80cab19fce03 202 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 130 146 5.1E-43 T 23-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 A3L08_02250 180a0afe2eb5a63a187c80cab19fce03 202 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 3 26 5.1E-43 T 23-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 A3L08_02250 180a0afe2eb5a63a187c80cab19fce03 202 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 78 98 5.1E-43 T 23-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 A3L08_02250 180a0afe2eb5a63a187c80cab19fce03 202 ProSitePatterns PS01334 Pyrrolidone-carboxylate peptidase cysteine active site. 128 142 - T 23-10-2018 IPR033694 Pyroglutamyl peptidase I, Cys active site MetaCyc: PWY-7942 A3L08_02250 180a0afe2eb5a63a187c80cab19fce03 202 ProSitePatterns PS01333 Pyrrolidone-carboxylate peptidase glutamic acid active site. 67 83 - T 23-10-2018 IPR033693 Pyroglutamyl peptidase I, Glu active site MetaCyc: PWY-7942 A3L08_02250 180a0afe2eb5a63a187c80cab19fce03 202 SUPERFAMILY SSF53182 1 199 1.02E-68 T 23-10-2018 IPR036440 Peptidase C15, pyroglutamyl peptidase I-like superfamily MetaCyc: PWY-7942 A3L08_02250 180a0afe2eb5a63a187c80cab19fce03 202 TIGRFAM TIGR00504 pyro_pdase: pyroglutamyl-peptidase I 2 198 2.1E-73 T 23-10-2018 IPR029762 Pyroglutamyl peptidase I, bacterial-type GO:0005829|GO:0006508|GO:0008234|GO:0016920 MetaCyc: PWY-7942 A3L08_02250 180a0afe2eb5a63a187c80cab19fce03 202 PIRSF PIRSF015592 1 201 2.1E-77 T 23-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 A3L08_02250 180a0afe2eb5a63a187c80cab19fce03 202 Pfam PF01470 Pyroglutamyl peptidase 1 199 1.1E-74 T 23-10-2018 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like MetaCyc: PWY-7942 A3L08_02250 180a0afe2eb5a63a187c80cab19fce03 202 Hamap MF_00417 Pyrrolidone-carboxylate peptidase [pcp]. 1 198 37.307 T 23-10-2018 IPR029762 Pyroglutamyl peptidase I, bacterial-type GO:0005829|GO:0006508|GO:0008234|GO:0016920 MetaCyc: PWY-7942 A3L08_02250 180a0afe2eb5a63a187c80cab19fce03 202 Gene3D G3DSA:3.40.630.20 1 202 1.1E-75 T 23-10-2018 IPR036440 Peptidase C15, pyroglutamyl peptidase I-like superfamily MetaCyc: PWY-7942 A3L08_08915 413db88d7189db2794f93b06c05159be 198 SUPERFAMILY SSF53448 14 132 7.41E-9 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L08_08915 413db88d7189db2794f93b06c05159be 198 Gene3D G3DSA:3.90.550.10 16 196 5.6E-13 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L08_09285 bba7fc13d4d97e948e29e8a5256e7851 381 Pfam PF02926 THUMP domain 29 168 8.3E-27 T 23-10-2018 IPR004114 THUMP domain GO:0003723 A3L08_09285 bba7fc13d4d97e948e29e8a5256e7851 381 Pfam PF02568 Thiamine biosynthesis protein (ThiI) 178 369 1.7E-66 T 23-10-2018 IPR020536 Thil, AANH domain GO:0004810 KEGG: 00730+2.8.1.4 A3L08_09285 bba7fc13d4d97e948e29e8a5256e7851 381 Gene3D G3DSA:3.30.70.1510 2 84 8.4E-33 T 23-10-2018 A3L08_09285 bba7fc13d4d97e948e29e8a5256e7851 381 Gene3D G3DSA:3.40.50.620 178 377 1.8E-66 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L08_09285 bba7fc13d4d97e948e29e8a5256e7851 381 SUPERFAMILY SSF143437 2 176 1.74E-47 T 23-10-2018 A3L08_09285 bba7fc13d4d97e948e29e8a5256e7851 381 Gene3D G3DSA:3.30.2300.10 85 166 1.4E-29 T 23-10-2018 A3L08_09285 bba7fc13d4d97e948e29e8a5256e7851 381 SMART SM00981 74 168 9.6E-21 T 23-10-2018 IPR004114 THUMP domain GO:0003723 A3L08_09285 bba7fc13d4d97e948e29e8a5256e7851 381 TIGRFAM TIGR00342 TIGR00342: tRNA sulfurtransferase ThiI 5 366 5.0E-104 T 23-10-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 KEGG: 00730+2.8.1.4 A3L08_09285 bba7fc13d4d97e948e29e8a5256e7851 381 SUPERFAMILY SSF52402 178 337 8.38E-51 T 23-10-2018 A3L08_09285 bba7fc13d4d97e948e29e8a5256e7851 381 Hamap MF_00021 tRNA sulfurtransferase [thiI]. 1 381 126.308 T 23-10-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 KEGG: 00730+2.8.1.4 A3L08_09020 a583175fea22d67aabb7eb10f4a850de 325 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L08_09020 a583175fea22d67aabb7eb10f4a850de 325 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 13 306 6.8E-122 T 23-10-2018 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 A3L08_09020 a583175fea22d67aabb7eb10f4a850de 325 Pfam PF13732 Domain of unknown function (DUF4162) 219 304 6.1E-8 T 23-10-2018 IPR025302 Domain of unknown function DUF4162 A3L08_09020 a583175fea22d67aabb7eb10f4a850de 325 SMART SM00382 30 214 1.7E-11 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L08_09020 a583175fea22d67aabb7eb10f4a850de 325 Pfam PF00005 ABC transporter 22 164 1.5E-35 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L08_09020 a583175fea22d67aabb7eb10f4a850de 325 Gene3D G3DSA:3.40.50.300 1 233 6.6E-78 T 23-10-2018 A3L08_09020 a583175fea22d67aabb7eb10f4a850de 325 SUPERFAMILY SSF52540 4 226 7.38E-72 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_05900 3ee9d05285b0fdbdabfb0152236aceeb 294 Pfam PF03186 CobD/Cbib protein 8 268 3.6E-85 T 23-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 A3L08_05900 3ee9d05285b0fdbdabfb0152236aceeb 294 Hamap MF_00024 Cobalamin biosynthesis protein CbiB [cbiB]. 1 292 80.268 T 23-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 A3L08_05900 3ee9d05285b0fdbdabfb0152236aceeb 294 TIGRFAM TIGR00380 cobD: cobalamin biosynthesis protein CobD 3 284 3.4E-85 T 23-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 A3L08_07255 a65fa9afccd5282f487d1ad6bf17990b 413 Pfam PF00483 Nucleotidyl transferase 2 230 1.4E-47 T 23-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 A3L08_07255 a65fa9afccd5282f487d1ad6bf17990b 413 SUPERFAMILY SSF51161 240 359 4.37E-14 T 23-10-2018 IPR011004 Trimeric LpxA-like superfamily A3L08_07255 a65fa9afccd5282f487d1ad6bf17990b 413 SUPERFAMILY SSF53448 1 345 5.63E-75 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L08_07255 a65fa9afccd5282f487d1ad6bf17990b 413 Gene3D G3DSA:2.160.10.10 238 369 1.7E-17 T 23-10-2018 A3L08_07255 a65fa9afccd5282f487d1ad6bf17990b 413 Gene3D G3DSA:3.90.550.10 1 237 1.9E-75 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L08_07255 a65fa9afccd5282f487d1ad6bf17990b 413 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 313 346 4.9E-5 T 23-10-2018 IPR001451 Hexapeptide repeat A3L08_07255 a65fa9afccd5282f487d1ad6bf17990b 413 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 261 287 1.4E-4 T 23-10-2018 IPR001451 Hexapeptide repeat A3L08_05640 f79842df2c797980e3153dc439c70a9b 263 Pfam PF09171 N-glycosylase/DNA lyase 23 246 1.7E-83 T 23-10-2018 IPR015254 N-glycosylase/DNA lyase-like GO:0003906|GO:0016799 A3L08_05640 f79842df2c797980e3153dc439c70a9b 263 Gene3D G3DSA:1.10.340.30 41 188 1.5E-79 T 23-10-2018 A3L08_05640 f79842df2c797980e3153dc439c70a9b 263 Hamap MF_01168 N-glycosylase/DNA lyase. 20 257 39.252 T 23-10-2018 IPR016544 N-glycosylase/DNA lyase GO:0000702|GO:0003906|GO:0006284 A3L08_05640 f79842df2c797980e3153dc439c70a9b 263 SUPERFAMILY SSF48150 16 247 9.42E-79 T 23-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 A3L08_05640 f79842df2c797980e3153dc439c70a9b 263 Gene3D G3DSA:1.10.1670.10 20 251 1.5E-79 T 23-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 A3L08_05640 f79842df2c797980e3153dc439c70a9b 263 PIRSF PIRSF008955 12 263 1.8E-100 T 23-10-2018 IPR016544 N-glycosylase/DNA lyase GO:0000702|GO:0003906|GO:0006284 A3L08_03570 ae26c7d5caa69a5fb024a95c5d2fcf2f 410 Hamap MF_00119 Translation initiation factor 2 subunit gamma [eif2g]. 4 409 60.823 T 23-10-2018 IPR022424 Translation initiation factor 2, gamma subunit A3L08_03570 ae26c7d5caa69a5fb024a95c5d2fcf2f 410 Gene3D G3DSA:2.40.30.10 319 410 6.8E-34 T 23-10-2018 A3L08_03570 ae26c7d5caa69a5fb024a95c5d2fcf2f 410 PRINTS PR00315 GTP-binding elongation factor signature 13 26 4.1E-14 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L08_03570 ae26c7d5caa69a5fb024a95c5d2fcf2f 410 PRINTS PR00315 GTP-binding elongation factor signature 140 149 4.1E-14 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L08_03570 ae26c7d5caa69a5fb024a95c5d2fcf2f 410 PRINTS PR00315 GTP-binding elongation factor signature 103 114 4.1E-14 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L08_03570 ae26c7d5caa69a5fb024a95c5d2fcf2f 410 PRINTS PR00315 GTP-binding elongation factor signature 87 97 4.1E-14 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L08_03570 ae26c7d5caa69a5fb024a95c5d2fcf2f 410 Pfam PF03144 Elongation factor Tu domain 2 231 311 2.2E-11 T 23-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 A3L08_03570 ae26c7d5caa69a5fb024a95c5d2fcf2f 410 Pfam PF00009 Elongation factor Tu GTP binding domain 12 199 8.2E-37 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L08_03570 ae26c7d5caa69a5fb024a95c5d2fcf2f 410 Pfam PF09173 Initiation factor eIF2 gamma, C terminal 324 408 8.0E-31 T 23-10-2018 IPR015256 Translation initiation factor 2, gamma subunit, C-terminal A3L08_03570 ae26c7d5caa69a5fb024a95c5d2fcf2f 410 Gene3D G3DSA:3.40.50.300 3 203 2.0E-68 T 23-10-2018 A3L08_03570 ae26c7d5caa69a5fb024a95c5d2fcf2f 410 SUPERFAMILY SSF52540 4 209 1.11E-53 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_03570 ae26c7d5caa69a5fb024a95c5d2fcf2f 410 TIGRFAM TIGR03680 eif2g_arch: translation initiation factor 2, gamma subunit 8 409 8.6E-206 T 23-10-2018 IPR022424 Translation initiation factor 2, gamma subunit A3L08_03570 ae26c7d5caa69a5fb024a95c5d2fcf2f 410 SUPERFAMILY SSF50447 204 316 4.99E-38 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily A3L08_03570 ae26c7d5caa69a5fb024a95c5d2fcf2f 410 Gene3D G3DSA:2.40.30.10 204 318 2.9E-46 T 23-10-2018 A3L08_03570 ae26c7d5caa69a5fb024a95c5d2fcf2f 410 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 10 193 2.8E-18 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A3L08_03570 ae26c7d5caa69a5fb024a95c5d2fcf2f 410 SUPERFAMILY SSF50465 317 409 5.4E-33 T 23-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal A3L08_03270 a1c1b78b4f61ff3866751bbe0e12a933 223 Gene3D G3DSA:3.40.50.880 2 223 1.9E-78 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A3L08_03270 a1c1b78b4f61ff3866751bbe0e12a933 223 SUPERFAMILY SSF52317 3 221 8.2E-77 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A3L08_03270 a1c1b78b4f61ff3866751bbe0e12a933 223 Hamap MF_00421 Phosphoribosylformylglycinamidine synthase subunit PurQ [purQ]. 2 219 44.646 T 23-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A3L08_03270 a1c1b78b4f61ff3866751bbe0e12a933 223 SMART SM01211 1 221 1.2E-129 T 23-10-2018 A3L08_03270 a1c1b78b4f61ff3866751bbe0e12a933 223 TIGRFAM TIGR01737 FGAM_synth_I: phosphoribosylformylglycinamidine synthase I 2 220 1.6E-95 T 23-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A3L08_03270 a1c1b78b4f61ff3866751bbe0e12a933 223 PIRSF PIRSF001586 1 223 1.2E-82 T 23-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A3L08_03270 a1c1b78b4f61ff3866751bbe0e12a933 223 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 2 220 1.4E-49 T 23-10-2018 A3L08_07020 72eecf58c240d6bad501b6f4e2431500 866 SMART SM00382 50 428 0.0053 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L08_07020 72eecf58c240d6bad501b6f4e2431500 866 SMART SM00490 302 388 9.2E-17 T 23-10-2018 IPR001650 Helicase, C-terminal A3L08_07020 72eecf58c240d6bad501b6f4e2431500 866 Gene3D G3DSA:3.40.50.300 18 238 3.6E-53 T 23-10-2018 A3L08_07020 72eecf58c240d6bad501b6f4e2431500 866 Pfam PF00270 DEAD/DEAH box helicase 38 222 1.1E-26 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A3L08_07020 72eecf58c240d6bad501b6f4e2431500 866 SMART SM00487 33 259 2.2E-34 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A3L08_07020 72eecf58c240d6bad501b6f4e2431500 866 Gene3D G3DSA:3.40.50.300 263 420 1.6E-24 T 23-10-2018 A3L08_07020 72eecf58c240d6bad501b6f4e2431500 866 SUPERFAMILY SSF52540 49 395 3.12E-46 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_07020 72eecf58c240d6bad501b6f4e2431500 866 Pfam PF00271 Helicase conserved C-terminal domain 277 384 1.8E-15 T 23-10-2018 IPR001650 Helicase, C-terminal A3L08_07020 72eecf58c240d6bad501b6f4e2431500 866 Pfam PF08494 DEAD/H associated 642 830 3.6E-54 T 23-10-2018 IPR013701 DEAD/H associated GO:0005524|GO:0016818 A3L08_07020 72eecf58c240d6bad501b6f4e2431500 866 PIRSF PIRSF037307 9 865 1.2E-288 T 23-10-2018 IPR017170 Lhr-like ATP-dependent RNA helicase, predicted GO:0005524|GO:0016818 A3L08_05295 e0760d142da0c7867d0dc20dd4d1afde 605 SUPERFAMILY SSF48310 211 604 7.19E-146 T 23-10-2018 IPR036021 Aldehyde ferredoxin oxidoreductase-like, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 A3L08_05295 e0760d142da0c7867d0dc20dd4d1afde 605 SMART SM00790 4 207 1.0E-134 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 A3L08_05295 e0760d142da0c7867d0dc20dd4d1afde 605 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 223 601 1.6E-143 T 23-10-2018 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 A3L08_05295 e0760d142da0c7867d0dc20dd4d1afde 605 Gene3D G3DSA:1.10.599.10 240 601 7.7E-159 T 23-10-2018 IPR013985 Aldehyde ferredoxin oxidoreductase, domain 3 GO:0016625|GO:0051536|GO:0055114 KEGG: 00030+1.2.7.5 A3L08_05295 e0760d142da0c7867d0dc20dd4d1afde 605 Gene3D G3DSA:1.10.569.10 242 427 7.7E-159 T 23-10-2018 IPR013984 Aldehyde ferredoxin oxidoreductase, domain 2 A3L08_05295 e0760d142da0c7867d0dc20dd4d1afde 605 Gene3D G3DSA:3.60.9.10 1 211 1.1E-96 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily A3L08_05295 e0760d142da0c7867d0dc20dd4d1afde 605 SUPERFAMILY SSF56228 1 209 1.44E-80 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily A3L08_05295 e0760d142da0c7867d0dc20dd4d1afde 605 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 6 205 8.4E-84 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 A3L08_00725 7213180cd67014d4bdcf424fc7569566 246 SUPERFAMILY SSF52402 49 190 6.16E-15 T 23-10-2018 A3L08_00725 7213180cd67014d4bdcf424fc7569566 246 PIRSF PIRSF006601 1 246 3.5E-85 T 23-10-2018 IPR012096 ATPase, PP-loop, MJ1638-related A3L08_00725 7213180cd67014d4bdcf424fc7569566 246 Gene3D G3DSA:3.40.50.620 55 204 2.4E-10 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L08_02430 98f70f499d7c96aef9a613fd214bdfcf 380 Pfam PF00999 Sodium/hydrogen exchanger family 9 377 2.4E-65 T 23-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 A3L08_02430 98f70f499d7c96aef9a613fd214bdfcf 380 Gene3D G3DSA:1.20.1530.20 1 380 1.1E-98 T 23-10-2018 IPR038770 Sodium/solute symporter superfamily A3L08_00150 243d7a985257a5ad01e95f8a734561f2 211 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 2 203 4.8E-41 T 23-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A3L08_00150 243d7a985257a5ad01e95f8a734561f2 211 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 56 69 - T 23-10-2018 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A3L08_00150 243d7a985257a5ad01e95f8a734561f2 211 Hamap MF_01200_A Orotidine 5'-phosphate decarboxylase [pyrF]. 4 209 37.492 T 23-10-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A3L08_00150 243d7a985257a5ad01e95f8a734561f2 211 Gene3D G3DSA:3.20.20.70 3 209 5.6E-67 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L08_00150 243d7a985257a5ad01e95f8a734561f2 211 SUPERFAMILY SSF51366 2 208 2.73E-61 T 23-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 A3L08_00150 243d7a985257a5ad01e95f8a734561f2 211 SMART SM00934 3 203 4.8E-66 T 23-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A3L08_00150 243d7a985257a5ad01e95f8a734561f2 211 TIGRFAM TIGR01740 pyrF: orotidine 5'-phosphate decarboxylase 4 203 1.9E-51 T 23-10-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A3L08_03245 f385cb4e65ef91073611eb3f3bfcef45 422 SUPERFAMILY SSF56059 118 324 1.68E-51 T 23-10-2018 A3L08_03245 f385cb4e65ef91073611eb3f3bfcef45 422 Hamap MF_01643 Formate-dependent phosphoribosylglycinamide formyltransferase [purT]. 12 411 49.063 T 23-10-2018 IPR005862 Formate-dependent phosphoribosylglycinamide formyltransferase GO:0000287|GO:0004644|GO:0005524|GO:0009152|GO:0016742 A3L08_03245 f385cb4e65ef91073611eb3f3bfcef45 422 Gene3D G3DSA:3.30.1490.20 129 200 5.0E-32 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 A3L08_03245 f385cb4e65ef91073611eb3f3bfcef45 422 Gene3D G3DSA:3.30.470.20 201 422 1.9E-76 T 23-10-2018 A3L08_03245 f385cb4e65ef91073611eb3f3bfcef45 422 SUPERFAMILY SSF52440 8 115 6.62E-34 T 23-10-2018 IPR016185 Pre-ATP-grasp domain superfamily A3L08_03245 f385cb4e65ef91073611eb3f3bfcef45 422 Pfam PF02222 ATP-grasp domain 127 303 3.6E-55 T 23-10-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type A3L08_03245 f385cb4e65ef91073611eb3f3bfcef45 422 TIGRFAM TIGR01142 purT: phosphoribosylglycinamide formyltransferase 2 18 410 1.2E-189 T 23-10-2018 IPR005862 Formate-dependent phosphoribosylglycinamide formyltransferase GO:0000287|GO:0004644|GO:0005524|GO:0009152|GO:0016742 A3L08_03245 f385cb4e65ef91073611eb3f3bfcef45 422 SUPERFAMILY SSF51246 339 410 9.73E-18 T 23-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 A3L08_03245 f385cb4e65ef91073611eb3f3bfcef45 422 Gene3D G3DSA:3.40.50.20 1 128 7.0E-57 T 23-10-2018 A3L08_00505 215ecd01bf769fc90971f1246da4ef2b 179 Gene3D G3DSA:1.10.260.40 81 179 5.9E-10 T 23-10-2018 A3L08_00505 215ecd01bf769fc90971f1246da4ef2b 179 SUPERFAMILY SSF47413 83 144 5.04E-7 T 23-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A3L08_00505 215ecd01bf769fc90971f1246da4ef2b 179 SMART SM00530 92 147 1.9E-5 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A3L08_00505 215ecd01bf769fc90971f1246da4ef2b 179 TIGRFAM TIGR00270 TIGR00270: TIGR00270 family protein 8 173 1.9E-21 T 23-10-2018 IPR004451 Conserved hypothetical protein CHP00270 A3L08_00505 215ecd01bf769fc90971f1246da4ef2b 179 Pfam PF01381 Helix-turn-helix 96 144 1.7E-6 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A3L08_08000 03eab7857c6a4a777b5eab9307063b91 138 Gene3D G3DSA:3.30.70.1150 51 138 2.7E-35 T 23-10-2018 IPR027271 Acetolactate synthase/Transcription factor NikR, C-terminal A3L08_08000 03eab7857c6a4a777b5eab9307063b91 138 Pfam PF08753 NikR C terminal nickel binding domain 55 131 3.7E-32 T 23-10-2018 IPR014864 Transcription factor, NikR, nickel binding C-terminal A3L08_08000 03eab7857c6a4a777b5eab9307063b91 138 Hamap MF_00476 Nickel-responsive regulator [nikR]. 3 133 29.769 T 23-10-2018 IPR022988 Nickel-responsive transcriptional regulator NikR GO:0003677|GO:0006355|GO:0010045|GO:0016151 A3L08_08000 03eab7857c6a4a777b5eab9307063b91 138 SUPERFAMILY SSF55021 53 133 2.29E-27 T 23-10-2018 A3L08_08000 03eab7857c6a4a777b5eab9307063b91 138 SUPERFAMILY SSF47598 3 48 1.93E-13 T 23-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 A3L08_08000 03eab7857c6a4a777b5eab9307063b91 138 Pfam PF01402 Ribbon-helix-helix protein, copG family 5 42 2.4E-8 T 23-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 A3L08_08000 03eab7857c6a4a777b5eab9307063b91 138 Gene3D G3DSA:1.10.1220.10 10 50 4.4E-22 T 23-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 A3L08_03905 ce78d53e6000b22b5135d4d54b9d864d 157 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 113 130 - T 23-10-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A3L08_03905 ce78d53e6000b22b5135d4d54b9d864d 157 Pfam PF00364 Biotin-requiring enzyme 91 156 6.9E-25 T 23-10-2018 IPR000089 Biotin/lipoyl attachment A3L08_03905 ce78d53e6000b22b5135d4d54b9d864d 157 SUPERFAMILY SSF51230 80 156 1.05E-26 T 23-10-2018 IPR011053 Single hybrid motif A3L08_03905 ce78d53e6000b22b5135d4d54b9d864d 157 Gene3D G3DSA:2.40.50.100 83 157 1.6E-29 T 23-10-2018 A3L08_03095 fd813e7caea19419bc180078c11f72e6 128 Gene3D G3DSA:3.40.50.300 2 125 2.8E-15 T 23-10-2018 A3L08_03095 fd813e7caea19419bc180078c11f72e6 128 SUPERFAMILY SSF52540 10 105 3.02E-10 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_03095 fd813e7caea19419bc180078c11f72e6 128 Pfam PF02223 Thymidylate kinase 10 106 8.9E-10 T 23-10-2018 IPR039430 Thymidylate kinase-like domain KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210 A3L08_02625 d29755a389b2aa8e987704c6469624b2 321 Gene3D G3DSA:1.10.3720.10 83 307 4.9E-8 T 23-10-2018 IPR035906 MetI-like superfamily A3L08_02625 d29755a389b2aa8e987704c6469624b2 321 SUPERFAMILY SSF161098 84 283 1.96E-8 T 23-10-2018 IPR035906 MetI-like superfamily A3L08_02625 d29755a389b2aa8e987704c6469624b2 321 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 103 315 7.0E-20 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A3L08_06430 67e0123eede3d724514df7c61bbef122 130 TIGRFAM TIGR00004 TIGR00004: reactive intermediate/imine deaminase 4 129 8.4E-53 T 23-10-2018 IPR006056 RidA family Reactome: R-HSA-8849175 A3L08_06430 67e0123eede3d724514df7c61bbef122 130 Gene3D G3DSA:3.30.1330.40 1 130 5.1E-57 T 23-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 A3L08_06430 67e0123eede3d724514df7c61bbef122 130 Pfam PF01042 Endoribonuclease L-PSP 9 129 3.9E-46 T 23-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 A3L08_06430 67e0123eede3d724514df7c61bbef122 130 SUPERFAMILY SSF55298 3 130 4.4E-49 T 23-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 A3L08_06430 67e0123eede3d724514df7c61bbef122 130 ProSitePatterns PS01094 Uncharacterized protein family UPF0076 signature. 106 124 - T 23-10-2018 IPR019897 RidA, conserved site Reactome: R-HSA-8849175 A3L08_06260 7100babd696cf92507ecba7e81a73a7f 377 Gene3D G3DSA:3.40.50.2000 183 347 3.2E-137 T 23-10-2018 A3L08_06260 7100babd696cf92507ecba7e81a73a7f 377 Gene3D G3DSA:3.40.50.2000 6 357 3.2E-137 T 23-10-2018 A3L08_06260 7100babd696cf92507ecba7e81a73a7f 377 TIGRFAM TIGR00236 wecB: UDP-N-acetylglucosamine 2-epimerase 5 362 3.0E-132 T 23-10-2018 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 A3L08_06260 7100babd696cf92507ecba7e81a73a7f 377 SUPERFAMILY SSF53756 4 364 1.53E-124 T 23-10-2018 A3L08_06260 7100babd696cf92507ecba7e81a73a7f 377 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 27 360 8.2E-121 T 23-10-2018 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 A3L08_06710 95517ad0386a7af039406635fd063262 254 Pfam PF01925 Sulfite exporter TauE/SafE 8 244 6.6E-59 T 23-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 A3L08_05005 8edd6eb7a9f431b4576cc84678be4e55 502 SUPERFAMILY SSF53383 12 488 8.68E-122 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A3L08_05005 8edd6eb7a9f431b4576cc84678be4e55 502 Hamap MF_00713 Probable glycine dehydrogenase (decarboxylating) subunit 2 [gcvPB]. 10 490 61.166 T 23-10-2018 IPR023012 Probable glycine dehydrogenase (decarboxylating) subunit 2 GO:0004375|GO:0019464 KEGG: 00260+1.4.4.2 A3L08_05005 8edd6eb7a9f431b4576cc84678be4e55 502 Gene3D G3DSA:3.90.1150.10 340 475 4.8E-44 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A3L08_05005 8edd6eb7a9f431b4576cc84678be4e55 502 Pfam PF02347 Glycine cleavage system P-protein 33 307 8.2E-11 T 23-10-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 A3L08_05005 8edd6eb7a9f431b4576cc84678be4e55 502 Gene3D G3DSA:3.40.640.10 86 316 2.5E-60 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A3L08_02645 edc693946cb72afb592d0413c18550a1 233 Pfam PF00175 Oxidoreductase NAD-binding domain 94 183 2.3E-6 T 23-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 A3L08_02645 edc693946cb72afb592d0413c18550a1 233 PRINTS PR00409 Phthalate dioxygenase reductase family signature 93 112 5.4E-5 T 23-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 A3L08_02645 edc693946cb72afb592d0413c18550a1 233 PRINTS PR00409 Phthalate dioxygenase reductase family signature 170 178 5.4E-5 T 23-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 A3L08_02645 edc693946cb72afb592d0413c18550a1 233 SUPERFAMILY SSF63380 4 85 1.2E-18 T 23-10-2018 IPR017938 Riboflavin synthase-like beta-barrel A3L08_02645 edc693946cb72afb592d0413c18550a1 233 Gene3D G3DSA:2.40.30.10 3 84 1.5E-11 T 23-10-2018 A3L08_02645 edc693946cb72afb592d0413c18550a1 233 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 197 229 4.8E-10 T 23-10-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain A3L08_02645 edc693946cb72afb592d0413c18550a1 233 Hamap MF_01211 Dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit [pyrK]. 2 231 34.136 T 23-10-2018 IPR023455 Dihydroorotate dehydrogenase electron transfer subunit A3L08_02645 edc693946cb72afb592d0413c18550a1 233 SUPERFAMILY SSF52343 80 228 1.83E-32 T 23-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A3L08_02645 edc693946cb72afb592d0413c18550a1 233 Gene3D G3DSA:3.40.50.80 86 196 1.3E-26 T 23-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A3L08_02645 edc693946cb72afb592d0413c18550a1 233 PIRSF PIRSF006816 2 232 3.1E-75 T 23-10-2018 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 A3L08_04625 80d7a515bb5efe810989241ce3ba953a 406 SUPERFAMILY SSF53697 215 404 1.37E-39 T 23-10-2018 A3L08_04625 80d7a515bb5efe810989241ce3ba953a 406 SMART SM00934 2 203 1.5E-43 T 23-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A3L08_04625 80d7a515bb5efe810989241ce3ba953a 406 SUPERFAMILY SSF51366 2 214 2.02E-44 T 23-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 A3L08_04625 80d7a515bb5efe810989241ce3ba953a 406 Pfam PF01380 SIS domain 246 347 2.7E-21 T 23-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 A3L08_04625 80d7a515bb5efe810989241ce3ba953a 406 Gene3D G3DSA:3.40.50.10490 213 406 1.3E-58 T 23-10-2018 A3L08_04625 80d7a515bb5efe810989241ce3ba953a 406 Gene3D G3DSA:3.20.20.70 1 208 1.0E-74 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L08_04625 80d7a515bb5efe810989241ce3ba953a 406 TIGRFAM TIGR03127 RuMP_HxlB: 6-phospho 3-hexuloisomerase 219 406 1.0E-74 T 23-10-2018 IPR017552 3-hexulose-6-phosphate isomerase GO:0016853 A3L08_04625 80d7a515bb5efe810989241ce3ba953a 406 TIGRFAM TIGR03128 RuMP_HxlA: 3-hexulose-6-phosphate synthase 3 206 1.2E-82 T 23-10-2018 IPR017553 3-hexulose-6-phosphate synthase GO:0005975|GO:0043801 KEGG: 00030+4.1.2.43|KEGG: 00680+4.1.2.43|MetaCyc: PWY-1861|MetaCyc: PWY-7796 A3L08_04625 80d7a515bb5efe810989241ce3ba953a 406 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 3 203 1.2E-26 T 23-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A3L08_02465 2d07899a285967ea1bf99838ff4ef930 916 Hamap MF_00036_A Alanine--tRNA ligase [alaS]. 4 912 24.242 T 23-10-2018 IPR022429 Alanine-tRNA ligase, archaea GO:0000166|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 A3L08_02465 2d07899a285967ea1bf99838ff4ef930 916 Gene3D G3DSA:3.30.54.20 678 729 5.0E-30 T 23-10-2018 A3L08_02465 2d07899a285967ea1bf99838ff4ef930 916 SUPERFAMILY SSF50447 515 600 2.68E-19 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily A3L08_02465 2d07899a285967ea1bf99838ff4ef930 916 Gene3D G3DSA:3.30.930.10 1 260 7.6E-114 T 23-10-2018 A3L08_02465 2d07899a285967ea1bf99838ff4ef930 916 TIGRFAM TIGR03683 A-tRNA_syn_arch: alanine--tRNA ligase 4 914 0.0 T 23-10-2018 IPR022429 Alanine-tRNA ligase, archaea GO:0000166|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 A3L08_02465 2d07899a285967ea1bf99838ff4ef930 916 SUPERFAMILY SSF101353 305 519 5.89E-51 T 23-10-2018 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain superfamily GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 A3L08_02465 2d07899a285967ea1bf99838ff4ef930 916 Pfam PF01411 tRNA synthetases class II (A) 61 606 2.2E-162 T 23-10-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 A3L08_02465 2d07899a285967ea1bf99838ff4ef930 916 SUPERFAMILY SSF55681 57 264 1.99E-57 T 23-10-2018 A3L08_02465 2d07899a285967ea1bf99838ff4ef930 916 Pfam PF02272 DHHA1 domain 785 914 8.9E-19 T 23-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 A3L08_02465 2d07899a285967ea1bf99838ff4ef930 916 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 61 896 1.8E-236 T 23-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 A3L08_02465 2d07899a285967ea1bf99838ff4ef930 916 SUPERFAMILY SSF55186 606 755 4.97E-49 T 23-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 A3L08_02465 2d07899a285967ea1bf99838ff4ef930 916 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 705 747 8.5E-16 T 23-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 A3L08_02465 2d07899a285967ea1bf99838ff4ef930 916 Gene3D G3DSA:3.10.310.40 816 916 2.0E-19 T 23-10-2018 A3L08_02465 2d07899a285967ea1bf99838ff4ef930 916 Gene3D G3DSA:3.30.980.10 608 677 1.2E-21 T 23-10-2018 A3L08_02465 2d07899a285967ea1bf99838ff4ef930 916 PRINTS PR00980 Alanyl-tRNA synthetase signature 245 258 4.2E-21 T 23-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 A3L08_02465 2d07899a285967ea1bf99838ff4ef930 916 PRINTS PR00980 Alanyl-tRNA synthetase signature 127 138 4.2E-21 T 23-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 A3L08_02465 2d07899a285967ea1bf99838ff4ef930 916 PRINTS PR00980 Alanyl-tRNA synthetase signature 206 217 4.2E-21 T 23-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 A3L08_02465 2d07899a285967ea1bf99838ff4ef930 916 PRINTS PR00980 Alanyl-tRNA synthetase signature 336 352 4.2E-21 T 23-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 A3L08_02465 2d07899a285967ea1bf99838ff4ef930 916 PRINTS PR00980 Alanyl-tRNA synthetase signature 360 373 4.2E-21 T 23-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 A3L08_02465 2d07899a285967ea1bf99838ff4ef930 916 SMART SM00863 705 748 2.7E-18 T 23-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 A3L08_02465 2d07899a285967ea1bf99838ff4ef930 916 Gene3D G3DSA:2.40.30.130 505 602 2.8E-36 T 23-10-2018 A3L08_02350 0bfb3a107d34094cb9e52d891ea1d05e 311 SUPERFAMILY SSF64182 3 310 5.76E-28 T 23-10-2018 IPR038763 DHH phosphoesterase superfamily A3L08_02350 0bfb3a107d34094cb9e52d891ea1d05e 311 Pfam PF02272 DHHA1 domain 192 310 7.2E-6 T 23-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 A3L08_06605 3b3667c304b07e8c443b7f72e9fd6c8e 230 Gene3D G3DSA:3.40.50.700 2 155 1.6E-33 T 23-10-2018 IPR037024 [NiFe]-hydrogenase, small subunit, N-terminal domain superfamily A3L08_06605 3b3667c304b07e8c443b7f72e9fd6c8e 230 Pfam PF13187 4Fe-4S dicluster domain 173 215 1.0E-7 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L08_06605 3b3667c304b07e8c443b7f72e9fd6c8e 230 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 14 131 1.0E-21 T 23-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L08_06605 3b3667c304b07e8c443b7f72e9fd6c8e 230 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 173 184 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L08_06605 3b3667c304b07e8c443b7f72e9fd6c8e 230 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 202 213 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L08_06605 3b3667c304b07e8c443b7f72e9fd6c8e 230 SUPERFAMILY SSF56770 3 214 2.75E-34 T 23-10-2018 A3L08_06605 3b3667c304b07e8c443b7f72e9fd6c8e 230 Gene3D G3DSA:3.30.70.20 158 220 2.9E-18 T 23-10-2018 A3L08_08010 a9fea0f2312727da21752f245765ac1f 101 ProSitePatterns PS00194 Thioredoxin family active site. 17 35 - T 23-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 A3L08_08010 a9fea0f2312727da21752f245765ac1f 101 Pfam PF00085 Thioredoxin 12 91 6.4E-14 T 23-10-2018 IPR013766 Thioredoxin domain GO:0045454 A3L08_08010 a9fea0f2312727da21752f245765ac1f 101 SUPERFAMILY SSF52833 13 96 2.91E-19 T 23-10-2018 IPR036249 Thioredoxin-like superfamily A3L08_08010 a9fea0f2312727da21752f245765ac1f 101 Gene3D G3DSA:3.40.30.10 4 100 2.7E-16 T 23-10-2018 A3L08_06615 1fb28fdd8103ace814ca1d7ef8e02186 622 Gene3D G3DSA:3.40.50.1980 68 198 4.1E-32 T 23-10-2018 A3L08_06615 1fb28fdd8103ace814ca1d7ef8e02186 622 SUPERFAMILY SSF53807 65 330 1.18E-67 T 23-10-2018 A3L08_06615 1fb28fdd8103ace814ca1d7ef8e02186 622 Gene3D G3DSA:3.40.50.1980 474 601 1.1E-35 T 23-10-2018 A3L08_06615 1fb28fdd8103ace814ca1d7ef8e02186 622 Gene3D G3DSA:3.40.50.1980 202 329 7.0E-34 T 23-10-2018 A3L08_06615 1fb28fdd8103ace814ca1d7ef8e02186 622 Gene3D G3DSA:3.40.50.1980 335 457 5.0E-35 T 23-10-2018 A3L08_06615 1fb28fdd8103ace814ca1d7ef8e02186 622 Pfam PF01497 Periplasmic binding protein 86 304 2.0E-32 T 23-10-2018 IPR002491 ABC transporter periplasmic binding domain A3L08_06615 1fb28fdd8103ace814ca1d7ef8e02186 622 Pfam PF01497 Periplasmic binding protein 357 575 1.8E-34 T 23-10-2018 IPR002491 ABC transporter periplasmic binding domain A3L08_06615 1fb28fdd8103ace814ca1d7ef8e02186 622 SUPERFAMILY SSF53807 341 606 3.73E-72 T 23-10-2018 A3L08_02135 61e1fc9ae154e7f06477edf486e61e5c 576 PRINTS PR00173 Glutamate-aspartate symporter signature 394 413 8.9E-6 T 23-10-2018 A3L08_02135 61e1fc9ae154e7f06477edf486e61e5c 576 PRINTS PR00173 Glutamate-aspartate symporter signature 266 285 8.9E-6 T 23-10-2018 A3L08_02135 61e1fc9ae154e7f06477edf486e61e5c 576 PRINTS PR00173 Glutamate-aspartate symporter signature 105 130 8.9E-6 T 23-10-2018 A3L08_02135 61e1fc9ae154e7f06477edf486e61e5c 576 PRINTS PR00173 Glutamate-aspartate symporter signature 13 33 8.9E-6 T 23-10-2018 A3L08_02135 61e1fc9ae154e7f06477edf486e61e5c 576 Pfam PF03169 OPT oligopeptide transporter protein 17 568 8.8E-65 T 23-10-2018 IPR004813 Oligopeptide transporter, OPT superfamily GO:0055085 A3L08_04670 f35a3b92e2881cf267cef1016d2d230d 232 Pfam PF13549 ATP-grasp domain 16 231 4.6E-83 T 23-10-2018 A3L08_04670 f35a3b92e2881cf267cef1016d2d230d 232 SUPERFAMILY SSF56059 23 232 1.01E-50 T 23-10-2018 A3L08_04670 f35a3b92e2881cf267cef1016d2d230d 232 Gene3D G3DSA:3.30.1490.20 39 116 2.1E-90 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 A3L08_04670 f35a3b92e2881cf267cef1016d2d230d 232 Gene3D G3DSA:3.30.470.20 21 230 2.1E-90 T 23-10-2018 A3L08_02765 349864d2fc073ccd32fd19bc61d1eaf3 420 Pfam PF00079 Serpin (serine protease inhibitor) 58 418 1.3E-115 T 23-10-2018 IPR023796 Serpin domain A3L08_02765 349864d2fc073ccd32fd19bc61d1eaf3 420 SUPERFAMILY SSF56574 37 418 9.82E-120 T 23-10-2018 IPR036186 Serpin superfamily A3L08_02765 349864d2fc073ccd32fd19bc61d1eaf3 420 SMART SM00093 63 418 8.5E-126 T 23-10-2018 IPR023796 Serpin domain A3L08_02765 349864d2fc073ccd32fd19bc61d1eaf3 420 ProSitePatterns PS00284 Serpins signature. 391 401 - T 23-10-2018 IPR023795 Serpin, conserved site A3L08_02765 349864d2fc073ccd32fd19bc61d1eaf3 420 Gene3D G3DSA:3.30.497.10 61 363 5.6E-122 T 23-10-2018 A3L08_02765 349864d2fc073ccd32fd19bc61d1eaf3 420 Gene3D G3DSA:2.30.39.10 220 418 5.6E-122 T 23-10-2018 A3L08_04650 a877553de0354e51ea08966f178c0f1a 1228 SMART SM00487 81 331 1.8E-21 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A3L08_04650 a877553de0354e51ea08966f178c0f1a 1228 SUPERFAMILY SSF52540 3 240 5.31E-33 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_04650 a877553de0354e51ea08966f178c0f1a 1228 Pfam PF01751 Toprim domain 644 805 4.6E-28 T 23-10-2018 IPR006171 TOPRIM domain A3L08_04650 a877553de0354e51ea08966f178c0f1a 1228 SMART SM00436 796 883 1.2E-41 T 23-10-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 A3L08_04650 a877553de0354e51ea08966f178c0f1a 1228 SUPERFAMILY SSF52540 326 625 1.48E-38 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_04650 a877553de0354e51ea08966f178c0f1a 1228 Gene3D G3DSA:1.10.290.10 926 1050 3.9E-139 T 23-10-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 A3L08_04650 a877553de0354e51ea08966f178c0f1a 1228 SUPERFAMILY SSF56712 637 1218 6.28E-142 T 23-10-2018 IPR023405 DNA topoisomerase, type IA, core domain A3L08_04650 a877553de0354e51ea08966f178c0f1a 1228 Hamap MF_01125 Reverse gyrase [rgy]. 1 1220 64.352 T 23-10-2018 IPR005736 Reverse gyrase GO:0003677|GO:0003916|GO:0006265 A3L08_04650 a877553de0354e51ea08966f178c0f1a 1228 Pfam PF00270 DEAD/DEAH box helicase 88 222 1.6E-10 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A3L08_04650 a877553de0354e51ea08966f178c0f1a 1228 Gene3D G3DSA:3.40.50.140 630 819 2.8E-30 T 23-10-2018 A3L08_04650 a877553de0354e51ea08966f178c0f1a 1228 SMART SM00437 916 1172 9.1E-95 T 23-10-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 A3L08_04650 a877553de0354e51ea08966f178c0f1a 1228 SMART SM00493 642 795 3.9E-44 T 23-10-2018 IPR006171 TOPRIM domain A3L08_04650 a877553de0354e51ea08966f178c0f1a 1228 Gene3D G3DSA:1.10.460.10 825 1213 3.9E-139 T 23-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 A3L08_04650 a877553de0354e51ea08966f178c0f1a 1228 Gene3D G3DSA:3.40.50.300 320 503 4.2E-33 T 23-10-2018 A3L08_04650 a877553de0354e51ea08966f178c0f1a 1228 Gene3D G3DSA:3.40.50.300 546 629 6.0E-15 T 23-10-2018 A3L08_04650 a877553de0354e51ea08966f178c0f1a 1228 Gene3D G3DSA:2.60.510.20 877 1117 3.9E-139 T 23-10-2018 A3L08_04650 a877553de0354e51ea08966f178c0f1a 1228 TIGRFAM TIGR01054 rgy: reverse gyrase 2 1218 0.0 T 23-10-2018 IPR005736 Reverse gyrase GO:0003677|GO:0003916|GO:0006265 A3L08_04650 a877553de0354e51ea08966f178c0f1a 1228 Pfam PF01131 DNA topoisomerase 820 1209 1.5E-79 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A3L08_04650 a877553de0354e51ea08966f178c0f1a 1228 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 855 873 9.7E-27 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A3L08_04650 a877553de0354e51ea08966f178c0f1a 1228 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 1039 1055 9.7E-27 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A3L08_04650 a877553de0354e51ea08966f178c0f1a 1228 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 769 782 9.7E-27 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A3L08_04650 a877553de0354e51ea08966f178c0f1a 1228 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 958 967 9.7E-27 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A3L08_04650 a877553de0354e51ea08966f178c0f1a 1228 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 1133 1147 9.7E-27 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A3L08_05130 b9743f91100c24ab185657ac8524114e 94 Gene3D G3DSA:3.10.450.80 1 93 8.7E-31 T 23-10-2018 A3L08_05130 b9743f91100c24ab185657ac8524114e 94 Pfam PF00935 Ribosomal protein L44 16 92 4.7E-26 T 23-10-2018 IPR000552 Ribosomal protein L44e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_05130 b9743f91100c24ab185657ac8524114e 94 ProDom PD002841 RIBOSOMAL RIBONUCLEOPROTEIN 60S L44 L44E L41 RESISTANCE 50S ANTIBIOTIC CYCLOHEXIMIDE 9 93 2.0E-40 T 23-10-2018 IPR000552 Ribosomal protein L44e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_05130 b9743f91100c24ab185657ac8524114e 94 SUPERFAMILY SSF57829 1 93 2.15E-30 T 23-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 A3L08_05130 b9743f91100c24ab185657ac8524114e 94 Hamap MF_01476 50S ribosomal protein L44e [rpl44e]. 1 92 24.828 T 23-10-2018 IPR000552 Ribosomal protein L44e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_05130 b9743f91100c24ab185657ac8524114e 94 ProSitePatterns PS01172 Ribosomal protein L44e signature. 60 71 - T 23-10-2018 IPR000552 Ribosomal protein L44e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_00700 0ff87a6704e7543d1d073fb8d86d89f1 239 Hamap MF_01633 7-cyano-7-deazaguanine synthase [queC]. 2 231 45.495 T 23-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 A3L08_00700 0ff87a6704e7543d1d073fb8d86d89f1 239 Pfam PF06508 Queuosine biosynthesis protein QueC 3 224 1.5E-62 T 23-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 A3L08_00700 0ff87a6704e7543d1d073fb8d86d89f1 239 SUPERFAMILY SSF52402 1 235 6.84E-51 T 23-10-2018 A3L08_00700 0ff87a6704e7543d1d073fb8d86d89f1 239 TIGRFAM TIGR00364 TIGR00364: queuosine biosynthesis protein QueC 4 218 1.9E-47 T 23-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 A3L08_00700 0ff87a6704e7543d1d073fb8d86d89f1 239 Gene3D G3DSA:3.40.50.620 1 235 1.3E-60 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L08_00700 0ff87a6704e7543d1d073fb8d86d89f1 239 PIRSF PIRSF006293 1 237 3.9E-68 T 23-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 A3L08_04200 b25a8eb87ec9ebe29c339f512ae12619 336 Hamap MF_01081 Probable tRNA pseudouridine synthase B [truB]. 40 325 51.625 T 23-10-2018 IPR026326 Probable tRNA pseudouridine synthase B, archaeal GO:0006396 A3L08_04200 b25a8eb87ec9ebe29c339f512ae12619 336 Gene3D G3DSA:3.30.2350.10 40 243 2.5E-147 T 23-10-2018 A3L08_04200 b25a8eb87ec9ebe29c339f512ae12619 336 TIGRFAM TIGR00451 unchar_dom_2: uncharacterized domain 2 240 320 2.5E-10 T 23-10-2018 IPR004521 Uncharacterised domain CHP00451 GO:0003723 A3L08_04200 b25a8eb87ec9ebe29c339f512ae12619 336 Gene3D G3DSA:2.30.130.70 23 332 2.5E-147 T 23-10-2018 A3L08_04200 b25a8eb87ec9ebe29c339f512ae12619 336 SUPERFAMILY SSF55120 21 247 9.11E-77 T 23-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 A3L08_04200 b25a8eb87ec9ebe29c339f512ae12619 336 TIGRFAM TIGR00425 CBF5: putative rRNA pseudouridine synthase 17 334 8.0E-136 T 23-10-2018 IPR004802 tRNA pseudouridine synthase B family GO:0006396 Reactome: R-HSA-171319|Reactome: R-HSA-6790901 A3L08_04200 b25a8eb87ec9ebe29c339f512ae12619 336 SUPERFAMILY SSF88697 249 332 1.27E-22 T 23-10-2018 IPR015947 PUA-like superfamily A3L08_04200 b25a8eb87ec9ebe29c339f512ae12619 336 Pfam PF08068 DKCLD (NUC011) domain 15 63 1.3E-18 T 23-10-2018 IPR012960 Dyskerin-like Reactome: R-HSA-171319|Reactome: R-HSA-6790901 A3L08_04200 b25a8eb87ec9ebe29c339f512ae12619 336 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 67 118 3.3E-15 T 23-10-2018 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 A3L08_04200 b25a8eb87ec9ebe29c339f512ae12619 336 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 120 180 1.5E-6 T 23-10-2018 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 A3L08_04200 b25a8eb87ec9ebe29c339f512ae12619 336 SMART SM01136 4 63 1.6E-25 T 23-10-2018 IPR012960 Dyskerin-like Reactome: R-HSA-171319|Reactome: R-HSA-6790901 A3L08_04200 b25a8eb87ec9ebe29c339f512ae12619 336 SMART SM00359 251 325 1.4E-20 T 23-10-2018 IPR002478 PUA domain GO:0003723 A3L08_04200 b25a8eb87ec9ebe29c339f512ae12619 336 Pfam PF01472 PUA domain 251 323 4.1E-20 T 23-10-2018 IPR002478 PUA domain GO:0003723 A3L08_04200 b25a8eb87ec9ebe29c339f512ae12619 336 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 181 247 1.4E-22 T 23-10-2018 IPR032819 tRNA pseudouridylate synthase B, C-terminal Reactome: R-HSA-171319|Reactome: R-HSA-6790901 A3L08_05510 cb943ba97c9f79bcbfb999989ee762ad 295 TIGRFAM TIGR00501 met_pdase_II: methionine aminopeptidase, type II 2 295 1.0E-118 T 23-10-2018 IPR002468 Peptidase M24A, methionine aminopeptidase, subfamily 2 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800|Reactome: R-HSA-2514859 A3L08_05510 cb943ba97c9f79bcbfb999989ee762ad 295 SUPERFAMILY SSF55920 3 295 1.13E-67 T 23-10-2018 IPR036005 Creatinase/aminopeptidase-like A3L08_05510 cb943ba97c9f79bcbfb999989ee762ad 295 PRINTS PR00599 Methionine aminopeptidase-1 signature 145 157 4.1E-16 T 23-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 A3L08_05510 cb943ba97c9f79bcbfb999989ee762ad 295 PRINTS PR00599 Methionine aminopeptidase-1 signature 53 66 4.1E-16 T 23-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 A3L08_05510 cb943ba97c9f79bcbfb999989ee762ad 295 PRINTS PR00599 Methionine aminopeptidase-1 signature 78 94 4.1E-16 T 23-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 A3L08_05510 cb943ba97c9f79bcbfb999989ee762ad 295 PRINTS PR00599 Methionine aminopeptidase-1 signature 177 189 4.1E-16 T 23-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 A3L08_05510 cb943ba97c9f79bcbfb999989ee762ad 295 Gene3D G3DSA:3.90.230.10 9 286 6.3E-109 T 23-10-2018 A3L08_05510 cb943ba97c9f79bcbfb999989ee762ad 295 ProSitePatterns PS01202 Methionine aminopeptidase subfamily 2 signature. 78 94 - T 23-10-2018 IPR018349 Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site MetaCyc: PWY-7799|MetaCyc: PWY-7800 A3L08_05510 cb943ba97c9f79bcbfb999989ee762ad 295 SUPERFAMILY SSF46785 196 271 2.18E-17 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L08_05510 cb943ba97c9f79bcbfb999989ee762ad 295 Pfam PF00557 Metallopeptidase family M24 7 287 3.2E-45 T 23-10-2018 IPR000994 Peptidase M24 A3L08_05510 cb943ba97c9f79bcbfb999989ee762ad 295 Hamap MF_01975 Methionine aminopeptidase [map]. 4 295 47.965 T 23-10-2018 IPR028595 Methionine aminopeptidase, archaeal GO:0004177|GO:0006508 MetaCyc: PWY-7799|MetaCyc: PWY-7800 A3L08_05510 cb943ba97c9f79bcbfb999989ee762ad 295 Gene3D G3DSA:1.10.10.10 196 272 6.3E-109 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L08_04000 e33776709089a21c000cb25fd0245559 953 Gene3D G3DSA:3.30.70.20 613 694 5.1E-13 T 23-10-2018 A3L08_04000 e33776709089a21c000cb25fd0245559 953 ProSitePatterns PS00641 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. 31 48 - T 23-10-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L08_04000 e33776709089a21c000cb25fd0245559 953 SUPERFAMILY SSF54862 580 693 1.9E-18 T 23-10-2018 A3L08_04000 e33776709089a21c000cb25fd0245559 953 SUPERFAMILY SSF54292 1 97 5.65E-24 T 23-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 A3L08_04000 e33776709089a21c000cb25fd0245559 953 PRINTS PR00419 Adrenodoxin reductase family signature 354 367 3.8E-22 T 23-10-2018 A3L08_04000 e33776709089a21c000cb25fd0245559 953 PRINTS PR00419 Adrenodoxin reductase family signature 321 335 3.8E-22 T 23-10-2018 A3L08_04000 e33776709089a21c000cb25fd0245559 953 PRINTS PR00419 Adrenodoxin reductase family signature 213 226 3.8E-22 T 23-10-2018 A3L08_04000 e33776709089a21c000cb25fd0245559 953 PRINTS PR00419 Adrenodoxin reductase family signature 255 265 3.8E-22 T 23-10-2018 A3L08_04000 e33776709089a21c000cb25fd0245559 953 PRINTS PR00419 Adrenodoxin reductase family signature 190 212 3.8E-22 T 23-10-2018 A3L08_04000 e33776709089a21c000cb25fd0245559 953 SUPERFAMILY SSF46548 96 199 4.81E-22 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 A3L08_04000 e33776709089a21c000cb25fd0245559 953 SUPERFAMILY SSF51971 187 429 5.65E-75 T 23-10-2018 A3L08_04000 e33776709089a21c000cb25fd0245559 953 Gene3D G3DSA:3.50.50.60 316 516 2.2E-31 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L08_04000 e33776709089a21c000cb25fd0245559 953 Gene3D G3DSA:3.50.50.60 186 314 4.3E-38 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L08_04000 e33776709089a21c000cb25fd0245559 953 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 98 176 8.2E-19 T 23-10-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 A3L08_04000 e33776709089a21c000cb25fd0245559 953 Gene3D G3DSA:3.10.20.740 1 115 3.4E-25 T 23-10-2018 A3L08_04000 e33776709089a21c000cb25fd0245559 953 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 189 482 4.6E-42 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A3L08_04000 e33776709089a21c000cb25fd0245559 953 SUPERFAMILY SSF53706 703 945 4.88E-14 T 23-10-2018 A3L08_04000 e33776709089a21c000cb25fd0245559 953 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 1 73 2.3E-10 T 23-10-2018 A3L08_04000 e33776709089a21c000cb25fd0245559 953 Gene3D G3DSA:2.20.25.90 706 756 3.9E-5 T 23-10-2018 A3L08_04580 e6c87266b2b0fac68659605a4ecf030f 416 PIRSF PIRSF037016 33 393 4.8E-63 T 23-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 A3L08_04580 e6c87266b2b0fac68659605a4ecf030f 416 PIRSF PIRSF037016 389 416 0.014 T 23-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 A3L08_04580 e6c87266b2b0fac68659605a4ecf030f 416 TIGRFAM TIGR00094 tRNA_TruD_broad: tRNA pseudouridine synthase, TruD family 12 415 1.3E-84 T 23-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 A3L08_04580 e6c87266b2b0fac68659605a4ecf030f 416 Gene3D G3DSA:1.10.1510.30 171 256 5.6E-117 T 23-10-2018 A3L08_04580 e6c87266b2b0fac68659605a4ecf030f 416 Gene3D G3DSA:3.30.70.3160 43 125 5.6E-117 T 23-10-2018 A3L08_04580 e6c87266b2b0fac68659605a4ecf030f 416 SUPERFAMILY SSF55120 7 414 1.04E-92 T 23-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 A3L08_04580 e6c87266b2b0fac68659605a4ecf030f 416 Hamap MF_01082 tRNA pseudouridine synthase D [truD]. 8 416 29.548 T 23-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 A3L08_04580 e6c87266b2b0fac68659605a4ecf030f 416 ProSitePatterns PS01268 Uncharacterized protein family UPF0024 signature. 80 93 - T 23-10-2018 IPR020119 Pseudouridine synthase TruD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 Reactome: R-HSA-6782315 A3L08_04580 e6c87266b2b0fac68659605a4ecf030f 416 Gene3D G3DSA:3.30.2350.20 126 411 5.6E-117 T 23-10-2018 A3L08_04580 e6c87266b2b0fac68659605a4ecf030f 416 Pfam PF01142 tRNA pseudouridine synthase D (TruD) 10 412 3.3E-135 T 23-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 A3L08_02540 a84ac72fb5dc3ef620de0af25d63b923 248 SUPERFAMILY SSF52540 3 235 2.63E-48 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_02540 a84ac72fb5dc3ef620de0af25d63b923 248 PRINTS PR01874 DNA repair protein radA signature 14 42 5.1E-10 T 23-10-2018 A3L08_02540 a84ac72fb5dc3ef620de0af25d63b923 248 PRINTS PR01874 DNA repair protein radA signature 135 159 5.1E-10 T 23-10-2018 A3L08_02540 a84ac72fb5dc3ef620de0af25d63b923 248 PRINTS PR01874 DNA repair protein radA signature 56 73 5.1E-10 T 23-10-2018 A3L08_02540 a84ac72fb5dc3ef620de0af25d63b923 248 Pfam PF06745 KaiC 5 237 8.2E-92 T 23-10-2018 IPR014774 KaiC-like domain A3L08_02540 a84ac72fb5dc3ef620de0af25d63b923 248 Gene3D G3DSA:3.40.50.300 1 247 4.8E-80 T 23-10-2018 A3L08_02540 a84ac72fb5dc3ef620de0af25d63b923 248 Hamap MF_01076 UPF0273 protein . 2 243 63.336 T 23-10-2018 IPR022475 Uncharacterised protein family UPF0273, KaiC-like A3L08_02540 a84ac72fb5dc3ef620de0af25d63b923 248 TIGRFAM TIGR03877 thermo_KaiC_1: KaiC domain protein, Ph0284 family 2 239 8.2E-142 T 23-10-2018 IPR022475 Uncharacterised protein family UPF0273, KaiC-like A3L08_07010 3bb2067b92bce5e59bef49ca770cbb65 617 Gene3D G3DSA:3.40.50.1820 2 611 1.5E-137 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold A3L08_07010 3bb2067b92bce5e59bef49ca770cbb65 617 SUPERFAMILY SSF53474 368 615 1.33E-49 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold A3L08_07010 3bb2067b92bce5e59bef49ca770cbb65 617 Pfam PF02897 Prolyl oligopeptidase, N-terminal beta-propeller domain 2 352 9.7E-19 T 23-10-2018 IPR023302 Peptidase S9A, N-terminal domain GO:0004252|GO:0070008 A3L08_07010 3bb2067b92bce5e59bef49ca770cbb65 617 Pfam PF00326 Prolyl oligopeptidase family 413 616 3.5E-54 T 23-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 A3L08_07010 3bb2067b92bce5e59bef49ca770cbb65 617 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 449 468 2.9E-52 T 23-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 A3L08_07010 3bb2067b92bce5e59bef49ca770cbb65 617 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 530 545 2.9E-52 T 23-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 A3L08_07010 3bb2067b92bce5e59bef49ca770cbb65 617 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 421 445 2.9E-52 T 23-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 A3L08_07010 3bb2067b92bce5e59bef49ca770cbb65 617 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 475 495 2.9E-52 T 23-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 A3L08_07010 3bb2067b92bce5e59bef49ca770cbb65 617 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 549 571 2.9E-52 T 23-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 A3L08_07010 3bb2067b92bce5e59bef49ca770cbb65 617 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 395 413 2.9E-52 T 23-10-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 A3L08_07010 3bb2067b92bce5e59bef49ca770cbb65 617 SUPERFAMILY SSF50993 2 367 3.4E-46 T 23-10-2018 A3L08_07010 3bb2067b92bce5e59bef49ca770cbb65 617 Gene3D G3DSA:2.130.10.120 49 362 1.5E-137 T 23-10-2018 A3L08_00680 b37866a299c4b43a80511dd54f1cf570 167 SUPERFAMILY SSF54862 4 137 2.24E-20 T 23-10-2018 A3L08_00680 b37866a299c4b43a80511dd54f1cf570 167 Gene3D G3DSA:3.30.70.20 37 106 2.0E-12 T 23-10-2018 A3L08_00680 b37866a299c4b43a80511dd54f1cf570 167 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 74 85 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L08_00680 b37866a299c4b43a80511dd54f1cf570 167 Pfam PF00037 4Fe-4S binding domain 67 88 1.5E-7 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L08_00715 215a50c2752645af787e18db54888ee9 225 SUPERFAMILY SSF81301 14 76 1.87E-9 T 23-10-2018 A3L08_00715 215a50c2752645af787e18db54888ee9 225 Pfam PF01909 Nucleotidyltransferase domain 18 89 4.7E-9 T 23-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 A3L08_00715 215a50c2752645af787e18db54888ee9 225 Gene3D G3DSA:3.30.460.10 3 87 4.3E-7 T 23-10-2018 A3L08_07315 55d7731e03114131beb28cbb991759b9 264 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L08_07315 55d7731e03114131beb28cbb991759b9 264 Pfam PF00005 ABC transporter 19 165 9.9E-27 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L08_07315 55d7731e03114131beb28cbb991759b9 264 SMART SM00382 28 215 5.7E-16 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L08_07315 55d7731e03114131beb28cbb991759b9 264 Gene3D G3DSA:3.40.50.300 1 239 3.0E-63 T 23-10-2018 A3L08_07315 55d7731e03114131beb28cbb991759b9 264 SUPERFAMILY SSF52540 4 228 9.35E-58 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_09780 0438b51a69c452be5bb83d7326ba4ff3 344 Pfam PF03459 TOBE domain 281 343 3.8E-16 T 23-10-2018 IPR005116 Transport-associated OB, type 1 A3L08_09780 0438b51a69c452be5bb83d7326ba4ff3 344 Gene3D G3DSA:2.40.50.140 245 343 1.2E-27 T 23-10-2018 A3L08_09780 0438b51a69c452be5bb83d7326ba4ff3 344 Pfam PF00005 ABC transporter 16 159 1.6E-32 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L08_09780 0438b51a69c452be5bb83d7326ba4ff3 344 SMART SM00382 25 271 4.7E-12 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L08_09780 0438b51a69c452be5bb83d7326ba4ff3 344 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L08_09780 0438b51a69c452be5bb83d7326ba4ff3 344 SUPERFAMILY SSF50331 235 344 3.4E-23 T 23-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal A3L08_09780 0438b51a69c452be5bb83d7326ba4ff3 344 Gene3D G3DSA:2.40.50.100 268 339 1.2E-27 T 23-10-2018 A3L08_09780 0438b51a69c452be5bb83d7326ba4ff3 344 Gene3D G3DSA:3.40.50.300 1 234 1.9E-73 T 23-10-2018 A3L08_09780 0438b51a69c452be5bb83d7326ba4ff3 344 SUPERFAMILY SSF52540 1 237 6.28E-80 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_09780 0438b51a69c452be5bb83d7326ba4ff3 344 TIGRFAM TIGR00638 Mop: molybdenum-pterin binding domain 279 343 5.4E-18 T 23-10-2018 IPR004606 Molybdenum-pterin binding GO:0015689 A3L08_05560 935cc89da626116ca0edcbe4cfadd705 264 Gene3D G3DSA:3.40.1180.10 20 264 2.3E-101 T 23-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 A3L08_05560 935cc89da626116ca0edcbe4cfadd705 264 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 34 263 8.6E-87 T 23-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 A3L08_05560 935cc89da626116ca0edcbe4cfadd705 264 Pfam PF01255 Putative undecaprenyl diphosphate synthase 41 263 3.9E-82 T 23-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 A3L08_05560 935cc89da626116ca0edcbe4cfadd705 264 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 209 226 - T 23-10-2018 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199|Reactome: R-HSA-4755609 A3L08_05560 935cc89da626116ca0edcbe4cfadd705 264 SUPERFAMILY SSF64005 32 259 2.09E-87 T 23-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 A3L08_05560 935cc89da626116ca0edcbe4cfadd705 264 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 34 264 39.658 T 23-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 A3L08_04440 3aeca90edb20d531f07c329a31ebf5ba 967 SUPERFAMILY SSF50677 210 443 3.4E-34 T 23-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 A3L08_04440 3aeca90edb20d531f07c329a31ebf5ba 967 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 12 689 7.0E-68 T 23-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L08_04440 3aeca90edb20d531f07c329a31ebf5ba 967 Gene3D G3DSA:3.90.740.10 205 451 1.4E-301 T 23-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 A3L08_04440 3aeca90edb20d531f07c329a31ebf5ba 967 Pfam PF08264 Anticodon-binding domain of tRNA 726 861 5.9E-32 T 23-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 A3L08_04440 3aeca90edb20d531f07c329a31ebf5ba 967 Hamap MF_00049_A Leucine--tRNA ligase [leuS]. 6 967 18.468 T 23-10-2018 IPR020791 Leucine-tRNA ligase, archaeal GO:0000166|GO:0004823|GO:0005524|GO:0005737|GO:0006429 KEGG: 00970+6.1.1.4 A3L08_04440 3aeca90edb20d531f07c329a31ebf5ba 967 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 43 54 - T 23-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L08_04440 3aeca90edb20d531f07c329a31ebf5ba 967 SUPERFAMILY SSF52374 4 694 8.7E-102 T 23-10-2018 A3L08_04440 3aeca90edb20d531f07c329a31ebf5ba 967 Gene3D G3DSA:1.10.10.720 866 917 2.9E-48 T 23-10-2018 A3L08_04440 3aeca90edb20d531f07c329a31ebf5ba 967 TIGRFAM TIGR00395 leuS_arch: leucine--tRNA ligase 8 967 0.0 T 23-10-2018 IPR004493 Leucyl-tRNA synthetase, class Ia, archaeal/eukaryotic cytosolic GO:0000166|GO:0004823|GO:0005524|GO:0005737|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A3L08_04440 3aeca90edb20d531f07c329a31ebf5ba 967 Gene3D G3DSA:3.30.2320.20 835 967 2.9E-48 T 23-10-2018 A3L08_04440 3aeca90edb20d531f07c329a31ebf5ba 967 Gene3D G3DSA:3.40.50.620 9 688 1.4E-301 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L08_04440 3aeca90edb20d531f07c329a31ebf5ba 967 SUPERFAMILY SSF47323 697 904 9.53E-41 T 23-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L08_04440 3aeca90edb20d531f07c329a31ebf5ba 967 Gene3D G3DSA:1.10.730.10 690 810 1.0E-36 T 23-10-2018 A3L08_02955 a6b453d0a3521f603316b92fddfa8489 272 Pfam PF13242 HAD-hyrolase-like 188 260 5.2E-21 T 23-10-2018 A3L08_02955 a6b453d0a3521f603316b92fddfa8489 272 Pfam PF13344 Haloacid dehalogenase-like hydrolase 7 106 8.1E-30 T 23-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA A3L08_02955 a6b453d0a3521f603316b92fddfa8489 272 Gene3D G3DSA:3.40.50.1000 8 254 2.9E-95 T 23-10-2018 IPR023214 HAD superfamily A3L08_02955 a6b453d0a3521f603316b92fddfa8489 272 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 8 236 3.5E-49 T 23-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA A3L08_02955 a6b453d0a3521f603316b92fddfa8489 272 PIRSF PIRSF000915 6 266 1.0E-65 T 23-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA A3L08_02955 a6b453d0a3521f603316b92fddfa8489 272 SUPERFAMILY SSF56784 7 261 9.49E-71 T 23-10-2018 IPR036412 HAD-like superfamily A3L08_02955 a6b453d0a3521f603316b92fddfa8489 272 Gene3D G3DSA:3.40.50.1000 72 188 2.9E-95 T 23-10-2018 IPR023214 HAD superfamily A3L08_00995 5333ca52d9983fbae3e26db697683fe0 167 SUPERFAMILY SSF55729 16 158 1.96E-40 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase A3L08_00995 5333ca52d9983fbae3e26db697683fe0 167 Gene3D G3DSA:3.40.630.30 16 163 3.8E-49 T 23-10-2018 A3L08_00995 5333ca52d9983fbae3e26db697683fe0 167 Pfam PF00583 Acetyltransferase (GNAT) family 28 137 2.8E-28 T 23-10-2018 IPR000182 GNAT domain A3L08_00995 5333ca52d9983fbae3e26db697683fe0 167 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 27 156 1.7E-36 T 23-10-2018 IPR006464 N-acetyltransferase RimI/Ard1 GO:0006474|GO:0016407 A3L08_03465 703a0b0dba5815eecb939b9905c0f830 264 SUPERFAMILY SSF56317 1 264 6.28E-77 T 23-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily A3L08_03465 703a0b0dba5815eecb939b9905c0f830 264 Pfam PF00795 Carbon-nitrogen hydrolase 2 244 2.7E-60 T 23-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 A3L08_03465 703a0b0dba5815eecb939b9905c0f830 264 Gene3D G3DSA:3.60.110.10 1 263 1.5E-103 T 23-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily A3L08_05965 110645e7036fe9e0e9c8ec38222dd95f 618 Gene3D G3DSA:3.60.9.10 1 207 2.3E-73 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily A3L08_05965 110645e7036fe9e0e9c8ec38222dd95f 618 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 218 598 1.8E-96 T 23-10-2018 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 A3L08_05965 110645e7036fe9e0e9c8ec38222dd95f 618 Gene3D G3DSA:1.10.569.10 237 428 5.5E-90 T 23-10-2018 IPR013984 Aldehyde ferredoxin oxidoreductase, domain 2 A3L08_05965 110645e7036fe9e0e9c8ec38222dd95f 618 SUPERFAMILY SSF48310 207 601 7.59E-104 T 23-10-2018 IPR036021 Aldehyde ferredoxin oxidoreductase-like, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 A3L08_05965 110645e7036fe9e0e9c8ec38222dd95f 618 SMART SM00790 4 204 1.1E-113 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 A3L08_05965 110645e7036fe9e0e9c8ec38222dd95f 618 Gene3D G3DSA:1.10.599.10 235 598 5.5E-90 T 23-10-2018 IPR013985 Aldehyde ferredoxin oxidoreductase, domain 3 GO:0016625|GO:0051536|GO:0055114 KEGG: 00030+1.2.7.5 A3L08_05965 110645e7036fe9e0e9c8ec38222dd95f 618 SUPERFAMILY SSF56228 1 203 4.71E-67 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily A3L08_05965 110645e7036fe9e0e9c8ec38222dd95f 618 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 7 200 9.2E-69 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 A3L08_00855 3114d3dd0abf3ca493635011285e5dba 317 SUPERFAMILY SSF102114 21 242 1.2E-36 T 23-10-2018 A3L08_00855 3114d3dd0abf3ca493635011285e5dba 317 Pfam PF04055 Radical SAM superfamily 39 196 8.9E-11 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L08_00855 3114d3dd0abf3ca493635011285e5dba 317 SMART SM00729 26 240 1.1E-17 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A3L08_00855 3114d3dd0abf3ca493635011285e5dba 317 Gene3D G3DSA:3.20.20.70 19 244 1.2E-23 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L08_00425 47057b89c598648787432144287107a6 290 Gene3D G3DSA:3.40.50.150 62 288 1.7E-74 T 23-10-2018 A3L08_00425 47057b89c598648787432144287107a6 290 Hamap MF_00198 Polyamine aminopropyltransferase [speE]. 8 286 35.781 T 23-10-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 A3L08_00425 47057b89c598648787432144287107a6 290 Gene3D G3DSA:2.30.140.10 6 60 3.0E-23 T 23-10-2018 IPR037163 Spermidine synthase, tetramerisation domain superfamily KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 A3L08_00425 47057b89c598648787432144287107a6 290 ProSitePatterns PS01330 Polyamine biosynthesis (PABS) domain signature. 84 97 - T 23-10-2018 IPR030373 Polyamine biosynthesis domain, conserved site KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 A3L08_00425 47057b89c598648787432144287107a6 290 TIGRFAM TIGR00417 speE: spermidine synthase 10 280 4.0E-79 T 23-10-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 A3L08_00425 47057b89c598648787432144287107a6 290 Pfam PF17284 Spermidine synthase tetramerisation domain 10 60 4.2E-13 T 23-10-2018 IPR035246 Spermidine synthase, tetramerisation domain KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 A3L08_00425 47057b89c598648787432144287107a6 290 SUPERFAMILY SSF53335 9 286 4.58E-73 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L08_00425 47057b89c598648787432144287107a6 290 Pfam PF01564 Spermine/spermidine synthase domain 64 247 2.8E-47 T 23-10-2018 A3L08_06425 960ba670726a2d7ecddb718a51182517 123 SUPERFAMILY SSF102712 3 121 5.23E-29 T 23-10-2018 A3L08_06425 960ba670726a2d7ecddb718a51182517 123 Gene3D G3DSA:3.40.140.10 2 123 6.0E-29 T 23-10-2018 A3L08_06425 960ba670726a2d7ecddb718a51182517 123 Pfam PF14464 Prokaryotic homologs of the JAB domain 10 101 1.5E-11 T 23-10-2018 IPR028090 JAB domain, prokaryotic A3L08_09820 3cc0325a134cd4bf22c7ee93c45cb34c 140 PIRSF PIRSF004681 2 133 4.7E-40 T 23-10-2018 IPR001602 Uncharacterised protein family UPF0047 A3L08_09820 3cc0325a134cd4bf22c7ee93c45cb34c 140 SUPERFAMILY SSF111038 3 131 4.32E-40 T 23-10-2018 IPR035917 YjbQ-like superfamily A3L08_09820 3cc0325a134cd4bf22c7ee93c45cb34c 140 Pfam PF01894 Uncharacterised protein family UPF0047 17 130 7.6E-37 T 23-10-2018 IPR001602 Uncharacterised protein family UPF0047 A3L08_09820 3cc0325a134cd4bf22c7ee93c45cb34c 140 Gene3D G3DSA:2.60.120.460 1 133 1.3E-47 T 23-10-2018 IPR035917 YjbQ-like superfamily A3L08_09820 3cc0325a134cd4bf22c7ee93c45cb34c 140 TIGRFAM TIGR00149 TIGR00149_YjbQ: secondary thiamine-phosphate synthase enzyme 4 131 1.3E-40 T 23-10-2018 IPR001602 Uncharacterised protein family UPF0047 A3L08_00280 0c38a28c1264c89551dd574942ca4264 326 ProSitePatterns PS00211 ABC transporters family signature. 153 167 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L08_00280 0c38a28c1264c89551dd574942ca4264 326 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 230 322 5.8E-28 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A3L08_00280 0c38a28c1264c89551dd574942ca4264 326 Gene3D G3DSA:3.40.50.300 3 326 2.5E-102 T 23-10-2018 A3L08_00280 0c38a28c1264c89551dd574942ca4264 326 SUPERFAMILY SSF52540 5 251 8.05E-77 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_00280 0c38a28c1264c89551dd574942ca4264 326 Pfam PF00005 ABC transporter 31 181 5.2E-33 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L08_00280 0c38a28c1264c89551dd574942ca4264 326 SMART SM00382 39 238 3.9E-14 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L08_00280 0c38a28c1264c89551dd574942ca4264 326 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 232 300 1.4E-19 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A3L08_07710 592fceaaa109ed4d06e665f6a5421685 159 Pfam PF00932 Lamin Tail Domain 46 159 2.2E-28 T 23-10-2018 IPR001322 Lamin tail domain A3L08_07710 592fceaaa109ed4d06e665f6a5421685 159 SUPERFAMILY SSF74853 44 157 1.83E-22 T 23-10-2018 IPR036415 Lamin tail domain superfamily A3L08_07710 592fceaaa109ed4d06e665f6a5421685 159 Gene3D G3DSA:2.60.40.1260 41 158 2.0E-6 T 23-10-2018 IPR036415 Lamin tail domain superfamily A3L08_04960 e6621cba835afafb6b48cf55b3596ad8 115 Gene3D G3DSA:3.10.530.10 50 113 7.5E-17 T 23-10-2018 IPR036593 CPE0013-like superfamily A3L08_04960 e6621cba835afafb6b48cf55b3596ad8 115 SUPERFAMILY SSF53706 3 52 6.81E-8 T 23-10-2018 A3L08_04960 e6621cba835afafb6b48cf55b3596ad8 115 Pfam PF07892 Protein of unknown function (DUF1667) 35 113 3.2E-28 T 23-10-2018 IPR012460 Protein of unknown function DUF1667 A3L08_04960 e6621cba835afafb6b48cf55b3596ad8 115 Gene3D G3DSA:2.20.25.90 1 49 2.1E-5 T 23-10-2018 A3L08_04960 e6621cba835afafb6b48cf55b3596ad8 115 SUPERFAMILY SSF160148 47 114 2.88E-20 T 23-10-2018 IPR036593 CPE0013-like superfamily A3L08_00520 701164d8201854316b1627911bd4a102 138 SUPERFAMILY SSF50249 8 116 2.06E-30 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L08_00520 701164d8201854316b1627911bd4a102 138 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 18 47 2.9E-6 T 23-10-2018 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal A3L08_00520 701164d8201854316b1627911bd4a102 138 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 51 112 6.3E-21 T 23-10-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal A3L08_08155 8f3cc2d2426e3bf8957aafc209bcda96 348 ProSitePatterns PS00106 Galactokinase signature. 7 18 - T 23-10-2018 IPR019741 Galactokinase, conserved site KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 A3L08_08155 8f3cc2d2426e3bf8957aafc209bcda96 348 Pfam PF00288 GHMP kinases N terminal domain 92 155 5.2E-14 T 23-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 A3L08_08155 8f3cc2d2426e3bf8957aafc209bcda96 348 PRINTS PR00959 Mevalonate kinase family signature 296 313 7.1E-41 T 23-10-2018 A3L08_08155 8f3cc2d2426e3bf8957aafc209bcda96 348 PRINTS PR00959 Mevalonate kinase family signature 136 155 7.1E-41 T 23-10-2018 A3L08_08155 8f3cc2d2426e3bf8957aafc209bcda96 348 PRINTS PR00959 Mevalonate kinase family signature 93 115 7.1E-41 T 23-10-2018 A3L08_08155 8f3cc2d2426e3bf8957aafc209bcda96 348 PRINTS PR00959 Mevalonate kinase family signature 5 29 7.1E-41 T 23-10-2018 A3L08_08155 8f3cc2d2426e3bf8957aafc209bcda96 348 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 95 106 - T 23-10-2018 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 A3L08_08155 8f3cc2d2426e3bf8957aafc209bcda96 348 Pfam PF10509 Galactokinase galactose-binding signature 5 35 1.4E-14 T 23-10-2018 IPR019539 Galactokinase galactose-binding domain GO:0005534 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 A3L08_08155 8f3cc2d2426e3bf8957aafc209bcda96 348 PIRSF PIRSF000530 1 348 7.8E-103 T 23-10-2018 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 A3L08_08155 8f3cc2d2426e3bf8957aafc209bcda96 348 Gene3D G3DSA:3.30.70.890 180 348 9.4E-57 T 23-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily A3L08_08155 8f3cc2d2426e3bf8957aafc209bcda96 348 PRINTS PR00473 Galactokinase signature 233 247 7.3E-21 T 23-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 A3L08_08155 8f3cc2d2426e3bf8957aafc209bcda96 348 PRINTS PR00473 Galactokinase signature 66 77 7.3E-21 T 23-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 A3L08_08155 8f3cc2d2426e3bf8957aafc209bcda96 348 PRINTS PR00473 Galactokinase signature 86 104 7.3E-21 T 23-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 A3L08_08155 8f3cc2d2426e3bf8957aafc209bcda96 348 PRINTS PR00473 Galactokinase signature 7 25 7.3E-21 T 23-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 A3L08_08155 8f3cc2d2426e3bf8957aafc209bcda96 348 Gene3D G3DSA:3.30.230.10 1 179 2.0E-58 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A3L08_08155 8f3cc2d2426e3bf8957aafc209bcda96 348 SUPERFAMILY SSF55060 179 347 1.01E-41 T 23-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily A3L08_08155 8f3cc2d2426e3bf8957aafc209bcda96 348 SUPERFAMILY SSF54211 2 177 8.35E-52 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A3L08_08155 8f3cc2d2426e3bf8957aafc209bcda96 348 Pfam PF08544 GHMP kinases C terminal 249 324 4.4E-14 T 23-10-2018 IPR013750 GHMP kinase, C-terminal domain A3L08_08155 8f3cc2d2426e3bf8957aafc209bcda96 348 TIGRFAM TIGR00131 gal_kin: galactokinase 2 347 3.8E-75 T 23-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 A3L08_05895 67c2849d5bf525fd509a8a752461d818 326 Pfam PF00155 Aminotransferase class I and II 26 315 1.8E-32 T 23-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A3L08_05895 67c2849d5bf525fd509a8a752461d818 326 Gene3D G3DSA:3.90.1150.10 19 316 2.0E-72 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A3L08_05895 67c2849d5bf525fd509a8a752461d818 326 Gene3D G3DSA:3.40.640.10 30 233 2.0E-72 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A3L08_05895 67c2849d5bf525fd509a8a752461d818 326 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 188 197 - T 23-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 A3L08_05895 67c2849d5bf525fd509a8a752461d818 326 SUPERFAMILY SSF53383 13 318 2.89E-57 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A3L08_07435 88f116c47ce11f5e60a767ed4b5b71a8 292 SUPERFAMILY SSF52540 93 247 1.68E-9 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_07435 88f116c47ce11f5e60a767ed4b5b71a8 292 Gene3D G3DSA:3.40.50.300 84 291 2.0E-7 T 23-10-2018 A3L08_07435 88f116c47ce11f5e60a767ed4b5b71a8 292 Pfam PF03477 ATP cone domain 13 86 5.2E-8 T 23-10-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 A3L08_07435 88f116c47ce11f5e60a767ed4b5b71a8 292 Hamap MF_00769 2-phosphoglycerate kinase [pgk2]. 5 292 42.464 T 23-10-2018 IPR020872 2-phosphoglycerate kinase GO:0016774 A3L08_00980 ea60afc234b03e062c77f0316ab3cb78 326 SUPERFAMILY SSF48019 235 324 2.41E-24 T 23-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 A3L08_00980 ea60afc234b03e062c77f0316ab3cb78 326 Gene3D G3DSA:3.40.50.300 1 169 2.3E-62 T 23-10-2018 A3L08_00980 ea60afc234b03e062c77f0316ab3cb78 326 SMART SM00382 45 172 6.1E-15 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L08_00980 ea60afc234b03e062c77f0316ab3cb78 326 Gene3D G3DSA:1.10.8.60 170 233 4.2E-27 T 23-10-2018 A3L08_00980 ea60afc234b03e062c77f0316ab3cb78 326 Hamap MF_01509 Replication factor C small subunit [rfcS]. 11 325 51.543 T 23-10-2018 IPR023748 Replication factor C small subunit, archaeal GO:0003689|GO:0005524|GO:0005663|GO:0006260 A3L08_00980 ea60afc234b03e062c77f0316ab3cb78 326 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 49 167 1.2E-18 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A3L08_00980 ea60afc234b03e062c77f0316ab3cb78 326 SUPERFAMILY SSF52540 12 227 2.49E-59 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_00980 ea60afc234b03e062c77f0316ab3cb78 326 Gene3D G3DSA:1.20.272.10 234 326 1.6E-37 T 23-10-2018 A3L08_00980 ea60afc234b03e062c77f0316ab3cb78 326 Pfam PF08542 Replication factor C C-terminal domain 235 320 1.0E-22 T 23-10-2018 IPR013748 Replication factor C, C-terminal Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-176187|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804756|Reactome: R-HSA-69091|Reactome: R-HSA-69473 A3L08_07590 ffa4a21c2f0456a53615a76d222b6d6e 551 Gene3D G3DSA:3.50.7.10 218 369 2.6E-218 T 23-10-2018 IPR027409 GroEL-like apical domain superfamily A3L08_07590 ffa4a21c2f0456a53615a76d222b6d6e 551 SUPERFAMILY SSF48592 17 524 1.7E-91 T 23-10-2018 IPR027413 GroEL-like equatorial domain superfamily A3L08_07590 ffa4a21c2f0456a53615a76d222b6d6e 551 Gene3D G3DSA:3.30.260.10 147 405 2.6E-218 T 23-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily A3L08_07590 ffa4a21c2f0456a53615a76d222b6d6e 551 Gene3D G3DSA:1.10.560.10 28 522 2.6E-218 T 23-10-2018 IPR027413 GroEL-like equatorial domain superfamily A3L08_07590 ffa4a21c2f0456a53615a76d222b6d6e 551 SUPERFAMILY SSF52029 212 378 2.03E-62 T 23-10-2018 IPR027409 GroEL-like apical domain superfamily A3L08_07590 ffa4a21c2f0456a53615a76d222b6d6e 551 ProSitePatterns PS00750 Chaperonins TCP-1 signature 1. 40 52 - T 23-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 A3L08_07590 ffa4a21c2f0456a53615a76d222b6d6e 551 Pfam PF00118 TCP-1/cpn60 chaperonin family 35 525 4.3E-183 T 23-10-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 A3L08_07590 ffa4a21c2f0456a53615a76d222b6d6e 551 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 59 77 8.2E-35 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 A3L08_07590 ffa4a21c2f0456a53615a76d222b6d6e 551 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 37 53 8.2E-35 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 A3L08_07590 ffa4a21c2f0456a53615a76d222b6d6e 551 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 407 419 8.2E-35 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 A3L08_07590 ffa4a21c2f0456a53615a76d222b6d6e 551 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 89 108 8.2E-35 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 A3L08_07590 ffa4a21c2f0456a53615a76d222b6d6e 551 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 373 395 8.2E-35 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 A3L08_07590 ffa4a21c2f0456a53615a76d222b6d6e 551 ProSitePatterns PS00995 Chaperonins TCP-1 signature 3. 89 97 - T 23-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 A3L08_07590 ffa4a21c2f0456a53615a76d222b6d6e 551 TIGRFAM TIGR02339 thermosome_arch: thermosome, various subunits, archaeal 8 525 5.1E-239 T 23-10-2018 IPR012714 Thermosome, archaeal GO:0005524|GO:0006457|GO:0051082 A3L08_07590 ffa4a21c2f0456a53615a76d222b6d6e 551 SUPERFAMILY SSF54849 149 405 1.86E-31 T 23-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily A3L08_07590 ffa4a21c2f0456a53615a76d222b6d6e 551 ProSitePatterns PS00751 Chaperonins TCP-1 signature 2. 61 77 - T 23-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 A3L08_09270 469aa51b067f0199c3b37aa4e675ed78 237 Pfam PF01177 Asp/Glu/Hydantoin racemase 8 212 4.6E-14 T 23-10-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A3L08_09270 469aa51b067f0199c3b37aa4e675ed78 237 PIRSF PIRSF015736 1 237 5.7E-91 T 23-10-2018 IPR026286 Maleate isomerase/Arylmalonate decarboxylase A3L08_09270 469aa51b067f0199c3b37aa4e675ed78 237 Gene3D G3DSA:3.40.50.12500 6 237 8.8E-88 T 23-10-2018 A3L08_00990 4aed0608cfb8e612c8be805c16bc4edb 171 SUPERFAMILY SSF53032 79 169 1.12E-28 T 23-10-2018 IPR036167 tRNA intron endonuclease, catalytic domain-like superfamily GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803|Reactome: R-HSA-6784531 A3L08_00990 4aed0608cfb8e612c8be805c16bc4edb 171 Pfam PF02778 tRNA intron endonuclease, N-terminal domain 8 69 5.1E-20 T 23-10-2018 IPR006678 tRNA intron endonuclease, N-terminal GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803|Reactome: R-HSA-6784531 A3L08_00990 4aed0608cfb8e612c8be805c16bc4edb 171 Pfam PF01974 tRNA intron endonuclease, catalytic C-terminal domain 80 163 1.3E-29 T 23-10-2018 IPR006677 tRNA intron endonuclease, catalytic domain-like GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803|Reactome: R-HSA-6784531 A3L08_00990 4aed0608cfb8e612c8be805c16bc4edb 171 SUPERFAMILY SSF55267 6 77 7.06E-19 T 23-10-2018 IPR036740 tRNA intron endonuclease, N-terminal domain superfamily GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803 A3L08_00990 4aed0608cfb8e612c8be805c16bc4edb 171 TIGRFAM TIGR00324 endA: tRNA-intron lyase 8 169 3.0E-38 T 23-10-2018 IPR006676 tRNA-splicing endonuclease GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803|Reactome: R-HSA-6784531 A3L08_00990 4aed0608cfb8e612c8be805c16bc4edb 171 Hamap MF_01833 tRNA-splicing endonuclease [endA]. 5 171 33.061 T 23-10-2018 IPR016442 tRNA-splicing endonuclease, archaeal short subfamily MetaCyc: PWY-6689|MetaCyc: PWY-7803 A3L08_00990 4aed0608cfb8e612c8be805c16bc4edb 171 Gene3D G3DSA:3.40.1170.20 8 73 1.4E-17 T 23-10-2018 A3L08_00990 4aed0608cfb8e612c8be805c16bc4edb 171 Gene3D G3DSA:3.40.1350.10 79 171 1.2E-31 T 23-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 A3L08_00990 4aed0608cfb8e612c8be805c16bc4edb 171 PIRSF PIRSF005285 8 171 5.4E-64 T 23-10-2018 IPR016442 tRNA-splicing endonuclease, archaeal short subfamily MetaCyc: PWY-6689|MetaCyc: PWY-7803 A3L08_03400 8f2163eadadd6e4b969fd16418adebfd 355 Pfam PF00717 Peptidase S24-like 36 94 1.8E-9 T 23-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C A3L08_03400 8f2163eadadd6e4b969fd16418adebfd 355 PRINTS PR00728 Eukaryotic signal peptidase (S26B) family signature 35 50 9.8E-7 T 23-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 A3L08_03400 8f2163eadadd6e4b969fd16418adebfd 355 PRINTS PR00728 Eukaryotic signal peptidase (S26B) family signature 86 97 9.8E-7 T 23-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 A3L08_03400 8f2163eadadd6e4b969fd16418adebfd 355 TIGRFAM TIGR02228 sigpep_I_arch: signal peptidase I 5 118 1.2E-20 T 23-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 A3L08_03400 8f2163eadadd6e4b969fd16418adebfd 355 Gene3D G3DSA:2.10.109.10 36 108 6.6E-6 T 23-10-2018 A3L08_03400 8f2163eadadd6e4b969fd16418adebfd 355 SUPERFAMILY SSF51306 36 118 5.23E-10 T 23-10-2018 IPR036286 LexA/Signal peptidase-like superfamily A3L08_04195 6192ebcdd8dea7f45746402baaccc107 236 Gene3D G3DSA:3.40.50.720 1 234 4.8E-54 T 23-10-2018 A3L08_04195 6192ebcdd8dea7f45746402baaccc107 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 145 164 3.0E-14 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L08_04195 6192ebcdd8dea7f45746402baaccc107 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 3.0E-14 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L08_04195 6192ebcdd8dea7f45746402baaccc107 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 74 85 3.0E-14 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L08_04195 6192ebcdd8dea7f45746402baaccc107 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 166 183 3.0E-14 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L08_04195 6192ebcdd8dea7f45746402baaccc107 236 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 74 85 2.6E-5 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L08_04195 6192ebcdd8dea7f45746402baaccc107 236 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 145 164 2.6E-5 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L08_04195 6192ebcdd8dea7f45746402baaccc107 236 SUPERFAMILY SSF51735 1 211 1.42E-50 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L08_04195 6192ebcdd8dea7f45746402baaccc107 236 Pfam PF00106 short chain dehydrogenase 2 184 2.2E-39 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L08_09130 9233631a6cfe3ed7811d4d62a7d66aa3 177 Gene3D G3DSA:3.40.50.300 1 177 7.0E-55 T 23-10-2018 A3L08_09130 9233631a6cfe3ed7811d4d62a7d66aa3 177 Hamap MF_00039 Putative adenylate kinase. 1 160 25.556 T 23-10-2018 IPR020618 Adenylate kinase isoenzyme 6 GO:0004017|GO:0005524 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A3L08_09130 9233631a6cfe3ed7811d4d62a7d66aa3 177 SUPERFAMILY SSF52540 2 154 1.15E-21 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_09130 9233631a6cfe3ed7811d4d62a7d66aa3 177 Pfam PF13238 AAA domain 3 116 1.0E-22 T 23-10-2018 A3L08_09315 30eb431eb54d9420fe0c802ee5e1a1df 473 Pfam PF13380 CoA binding domain 16 145 3.3E-25 T 23-10-2018 IPR003781 CoA-binding GO:0048037 A3L08_09315 30eb431eb54d9420fe0c802ee5e1a1df 473 SUPERFAMILY SSF51735 10 141 1.03E-38 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L08_09315 30eb431eb54d9420fe0c802ee5e1a1df 473 Gene3D G3DSA:3.40.50.261 142 306 6.5E-61 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A3L08_09315 30eb431eb54d9420fe0c802ee5e1a1df 473 Gene3D G3DSA:3.40.50.720 9 140 2.2E-43 T 23-10-2018 A3L08_09315 30eb431eb54d9420fe0c802ee5e1a1df 473 Gene3D G3DSA:3.40.50.261 308 472 2.6E-51 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A3L08_09315 30eb431eb54d9420fe0c802ee5e1a1df 473 SMART SM00881 12 111 4.6E-37 T 23-10-2018 IPR003781 CoA-binding GO:0048037 A3L08_09315 30eb431eb54d9420fe0c802ee5e1a1df 473 SUPERFAMILY SSF52210 143 304 4.32E-45 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A3L08_09315 30eb431eb54d9420fe0c802ee5e1a1df 473 SUPERFAMILY SSF52210 311 468 2.22E-40 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A3L08_09315 30eb431eb54d9420fe0c802ee5e1a1df 473 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 167 303 7.1E-57 T 23-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain A3L08_02230 6b5dc9584c3ac16f9bc073755480418f 277 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 232 245 - T 23-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 A3L08_02230 6b5dc9584c3ac16f9bc073755480418f 277 SUPERFAMILY SSF53613 2 274 1.26E-58 T 23-10-2018 IPR029056 Ribokinase-like A3L08_02230 6b5dc9584c3ac16f9bc073755480418f 277 Gene3D G3DSA:3.40.1190.20 2 276 9.8E-62 T 23-10-2018 IPR029056 Ribokinase-like A3L08_02230 6b5dc9584c3ac16f9bc073755480418f 277 PRINTS PR00990 Ribokinase signature 23 42 3.4E-7 T 23-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A3L08_02230 6b5dc9584c3ac16f9bc073755480418f 277 PRINTS PR00990 Ribokinase signature 162 177 3.4E-7 T 23-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A3L08_02230 6b5dc9584c3ac16f9bc073755480418f 277 PRINTS PR00990 Ribokinase signature 201 212 3.4E-7 T 23-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A3L08_02230 6b5dc9584c3ac16f9bc073755480418f 277 Pfam PF00294 pfkB family carbohydrate kinase 5 274 4.2E-43 T 23-10-2018 IPR011611 Carbohydrate kinase PfkB A3L08_01935 e62ee179bb2a622d16a5de5ac4ee1e8f 88 Pfam PF02597 ThiS family 5 88 8.5E-22 T 23-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 A3L08_01935 e62ee179bb2a622d16a5de5ac4ee1e8f 88 SUPERFAMILY SSF54285 1 86 4.3E-25 T 23-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp A3L08_01935 e62ee179bb2a622d16a5de5ac4ee1e8f 88 Gene3D G3DSA:3.10.20.30 1 88 8.2E-30 T 23-10-2018 IPR012675 Beta-grasp domain superfamily A3L08_01935 e62ee179bb2a622d16a5de5ac4ee1e8f 88 TIGRFAM TIGR01687 moaD_arch: MoaD family protein 3 88 2.4E-27 T 23-10-2018 IPR010038 MoaD, archaeal-type A3L08_09120 f62e80cbed5df05fe83912d56f945e62 255 Gene3D G3DSA:3.20.20.370 1 255 1.5E-113 T 23-10-2018 A3L08_09120 f62e80cbed5df05fe83912d56f945e62 255 Pfam PF03746 LamB/YcsF family 3 241 1.2E-106 T 23-10-2018 IPR005501 UPF0271 family, LamB/YcsF/PxpA KEGG: 00480+3.5.2.9|MetaCyc: PWY-4041|MetaCyc: PWY-7942 A3L08_09120 f62e80cbed5df05fe83912d56f945e62 255 Hamap MF_00691 UPF0271 protein YbgL [ybgL]. 1 245 47.888 T 23-10-2018 IPR005501 UPF0271 family, LamB/YcsF/PxpA KEGG: 00480+3.5.2.9|MetaCyc: PWY-4041|MetaCyc: PWY-7942 A3L08_09120 f62e80cbed5df05fe83912d56f945e62 255 SUPERFAMILY SSF88713 1 252 2.06E-106 T 23-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 A3L08_02830 69e6fb80c206ac16be973ebef5870c1d 340 SUPERFAMILY SSF159071 255 339 7.85E-19 T 23-10-2018 A3L08_02830 69e6fb80c206ac16be973ebef5870c1d 340 SUPERFAMILY SSF46785 3 95 9.25E-10 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L08_02830 69e6fb80c206ac16be973ebef5870c1d 340 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 10 77 2.6E-25 T 23-10-2018 IPR002831 Transcription regulator TrmB, N-terminal A3L08_02830 69e6fb80c206ac16be973ebef5870c1d 340 Gene3D G3DSA:1.10.10.10 2 100 9.9E-30 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L08_02830 69e6fb80c206ac16be973ebef5870c1d 340 Pfam PF11495 Archaeal transcriptional regulator TrmB 112 338 2.7E-53 T 23-10-2018 IPR021586 Transcription regulator TrmB, C-terminal A3L08_01540 e1f13e9b058acdfd0a1d98a10b8a3501 103 Gene3D G3DSA:3.30.70.1750 5 101 6.0E-30 T 23-10-2018 A3L08_01540 e1f13e9b058acdfd0a1d98a10b8a3501 103 Pfam PF11491 Protein of unknown function (DUF3213) 16 98 3.9E-38 T 23-10-2018 IPR021583 Protein of unknown function DUF3213 A3L08_09265 ae6595401667b5926747a7629bb66825 461 Gene3D G3DSA:3.40.1190.20 14 448 1.1E-159 T 23-10-2018 IPR029056 Ribokinase-like A3L08_09265 ae6595401667b5926747a7629bb66825 461 Pfam PF04587 ADP-specific Phosphofructokinase/Glucokinase conserved region 13 449 2.0E-110 T 23-10-2018 IPR007666 ADP-specific phosphofructokinase/glucokinase GO:0005975|GO:0016773 Reactome: R-HSA-70171 A3L08_09265 ae6595401667b5926747a7629bb66825 461 TIGRFAM TIGR02045 P_fruct_ADP: ADP-specific phosphofructokinase 13 458 7.2E-236 T 23-10-2018 IPR011790 ADP-specific phosphofructokinase, archaeal GO:0005737|GO:0006000|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.146|KEGG: 00030+2.7.1.146|KEGG: 00680+2.7.1.146|MetaCyc: PWY-6142 A3L08_09265 ae6595401667b5926747a7629bb66825 461 Gene3D G3DSA:3.30.1110.20 20 200 1.1E-159 T 23-10-2018 A3L08_09265 ae6595401667b5926747a7629bb66825 461 PIRSF PIRSF015883 1 458 3.8E-203 T 23-10-2018 IPR015990 ADP-specific phosphofructokinase/glucokinase, archaeal GO:0000287|GO:0006096|GO:0016773 A3L08_09265 ae6595401667b5926747a7629bb66825 461 SUPERFAMILY SSF53613 12 457 2.35E-157 T 23-10-2018 IPR029056 Ribokinase-like A3L08_09265 ae6595401667b5926747a7629bb66825 461 Hamap MF_00561 ADP-specific phosphofructokinase [pfkC]. 6 458 44.485 T 23-10-2018 IPR011790 ADP-specific phosphofructokinase, archaeal GO:0005737|GO:0006000|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.146|KEGG: 00030+2.7.1.146|KEGG: 00680+2.7.1.146|MetaCyc: PWY-6142 A3L08_05415 6cd7791483e261da2313b7d924aa08c8 783 Gene3D G3DSA:3.30.1490.20 3 197 1.3E-72 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 A3L08_05415 6cd7791483e261da2313b7d924aa08c8 783 TIGRFAM TIGR01418 PEP_synth: phosphoenolpyruvate synthase 7 770 6.4E-290 T 23-10-2018 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484|MetaCyc: PWY-6142 A3L08_05415 6cd7791483e261da2313b7d924aa08c8 783 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 676 694 - T 23-10-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 A3L08_05415 6cd7791483e261da2313b7d924aa08c8 783 PIRSF PIRSF000854 1 775 1.5E-205 T 23-10-2018 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484|MetaCyc: PWY-6142 A3L08_05415 6cd7791483e261da2313b7d924aa08c8 783 Gene3D G3DSA:3.30.470.20 198 354 1.2E-53 T 23-10-2018 A3L08_05415 6cd7791483e261da2313b7d924aa08c8 783 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 412 423 - T 23-10-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 A3L08_05415 6cd7791483e261da2313b7d924aa08c8 783 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 19 351 7.0E-119 T 23-10-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 A3L08_05415 6cd7791483e261da2313b7d924aa08c8 783 Pfam PF00391 PEP-utilising enzyme, mobile domain 381 453 2.7E-27 T 23-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 A3L08_05415 6cd7791483e261da2313b7d924aa08c8 783 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 676 691 1.3E-12 T 23-10-2018 A3L08_05415 6cd7791483e261da2313b7d924aa08c8 783 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 693 708 1.3E-12 T 23-10-2018 A3L08_05415 6cd7791483e261da2313b7d924aa08c8 783 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 512 531 1.3E-12 T 23-10-2018 A3L08_05415 6cd7791483e261da2313b7d924aa08c8 783 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 729 741 1.3E-12 T 23-10-2018 A3L08_05415 6cd7791483e261da2313b7d924aa08c8 783 SUPERFAMILY SSF56059 3 381 9.06E-107 T 23-10-2018 A3L08_05415 6cd7791483e261da2313b7d924aa08c8 783 Gene3D G3DSA:3.20.20.60 462 783 3.9E-103 T 23-10-2018 A3L08_05415 6cd7791483e261da2313b7d924aa08c8 783 SUPERFAMILY SSF51621 485 775 6.54E-93 T 23-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 A3L08_05415 6cd7791483e261da2313b7d924aa08c8 783 Gene3D G3DSA:3.50.30.10 355 461 7.7E-44 T 23-10-2018 A3L08_05415 6cd7791483e261da2313b7d924aa08c8 783 SUPERFAMILY SSF52009 353 461 2.62E-36 T 23-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 A3L08_05415 6cd7791483e261da2313b7d924aa08c8 783 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 479 769 2.4E-93 T 23-10-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 A3L08_00640 c047333b1c0cd17f14882cff3f69c022 386 SUPERFAMILY SSF51905 11 376 4.86E-60 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L08_00640 c047333b1c0cd17f14882cff3f69c022 386 Gene3D G3DSA:3.50.50.60 12 360 4.6E-141 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L08_00640 c047333b1c0cd17f14882cff3f69c022 386 Gene3D G3DSA:3.30.9.10 88 315 4.6E-141 T 23-10-2018 A3L08_00640 c047333b1c0cd17f14882cff3f69c022 386 Pfam PF01266 FAD dependent oxidoreductase 12 355 2.5E-74 T 23-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 A3L08_00640 c047333b1c0cd17f14882cff3f69c022 386 SUPERFAMILY SSF54373 224 316 1.05E-9 T 23-10-2018 A3L08_00560 2889414f4e3034f10ddeceeaf62fde0b 295 Pfam PF07722 Peptidase C26 3 222 4.5E-56 T 23-10-2018 IPR011697 Peptidase C26 GO:0016787 Reactome: R-HSA-6798695 A3L08_00560 2889414f4e3034f10ddeceeaf62fde0b 295 Gene3D G3DSA:3.40.50.880 1 250 4.3E-68 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A3L08_00560 2889414f4e3034f10ddeceeaf62fde0b 295 SUPERFAMILY SSF52317 3 243 9.35E-35 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A3L08_07715 3041332bc71c0af9cf5db43431194438 330 Gene3D G3DSA:3.40.50.150 143 330 1.5E-56 T 23-10-2018 A3L08_07715 3041332bc71c0af9cf5db43431194438 330 Gene3D G3DSA:3.30.300.110 61 142 9.4E-28 T 23-10-2018 A3L08_07715 3041332bc71c0af9cf5db43431194438 330 Pfam PF02475 Met-10+ like-protein 82 277 7.7E-71 T 23-10-2018 IPR030382 SAM-dependent methyltransferase TRM5/TYW2-type Reactome: R-HSA-6782861 A3L08_07715 3041332bc71c0af9cf5db43431194438 330 SUPERFAMILY SSF53335 72 329 4.18E-73 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L08_07715 3041332bc71c0af9cf5db43431194438 330 Gene3D G3DSA:3.30.70.2580 1 60 3.4E-5 T 23-10-2018 A3L08_08285 cfc8d4959741175c83955f0c153bc01f 257 Gene3D G3DSA:3.60.15.10 6 244 4.7E-43 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L08_08285 cfc8d4959741175c83955f0c153bc01f 257 Pfam PF00753 Metallo-beta-lactamase superfamily 34 224 3.7E-17 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L08_08285 cfc8d4959741175c83955f0c153bc01f 257 SUPERFAMILY SSF56281 30 251 2.52E-32 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L08_08285 cfc8d4959741175c83955f0c153bc01f 257 SMART SM00849 33 224 3.6E-18 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L08_02200 faec9656dd8fff6166dfb5833f2e6946 164 Gene3D G3DSA:2.40.50.100 97 163 1.1E-30 T 23-10-2018 A3L08_02200 faec9656dd8fff6166dfb5833f2e6946 164 Pfam PF09891 Uncharacterized protein conserved in archaea (DUF2118) 3 163 7.2E-55 T 23-10-2018 IPR019217 Protein of unknown function DUF2118 A3L08_02200 faec9656dd8fff6166dfb5833f2e6946 164 PIRSF PIRSF019115 1 164 4.5E-67 T 23-10-2018 IPR019217 Protein of unknown function DUF2118 A3L08_01230 bb9005932d79f9228edb5b3a000e2b49 428 PIRSF PIRSF000106 28 418 1.8E-75 T 23-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 A3L08_01230 bb9005932d79f9228edb5b3a000e2b49 428 SMART SM00919 158 388 2.4E-96 T 23-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 A3L08_01230 bb9005932d79f9228edb5b3a000e2b49 428 Pfam PF00390 Malic enzyme, N-terminal domain 23 146 6.7E-27 T 23-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 A3L08_01230 bb9005932d79f9228edb5b3a000e2b49 428 SMART SM01274 14 146 2.4E-77 T 23-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 A3L08_01230 bb9005932d79f9228edb5b3a000e2b49 428 Gene3D G3DSA:3.40.50.10380 2 155 3.0E-67 T 23-10-2018 IPR037062 Malic enzyme, N-terminal domain superfamily GO:0004471|GO:0055114 A3L08_01230 bb9005932d79f9228edb5b3a000e2b49 428 Gene3D G3DSA:3.40.50.720 156 428 8.3E-96 T 23-10-2018 A3L08_01230 bb9005932d79f9228edb5b3a000e2b49 428 SUPERFAMILY SSF51735 158 415 3.71E-64 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L08_01230 bb9005932d79f9228edb5b3a000e2b49 428 SUPERFAMILY SSF53223 11 156 1.29E-51 T 23-10-2018 A3L08_01230 bb9005932d79f9228edb5b3a000e2b49 428 Pfam PF03949 Malic enzyme, NAD binding domain 271 369 9.1E-10 T 23-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 A3L08_01230 bb9005932d79f9228edb5b3a000e2b49 428 Pfam PF03949 Malic enzyme, NAD binding domain 159 201 1.7E-5 T 23-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 A3L08_01230 bb9005932d79f9228edb5b3a000e2b49 428 ProSitePatterns PS00331 Malic enzymes signature. 154 170 - T 23-10-2018 IPR015884 Malic enzyme, conserved site GO:0004471|GO:0055114 A3L08_04615 02753d392becb811a876a4394359c575 214 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 128 144 2.5E-17 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L08_04615 02753d392becb811a876a4394359c575 214 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 98 111 2.5E-17 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L08_04615 02753d392becb811a876a4394359c575 214 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 1 12 2.5E-17 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L08_04615 02753d392becb811a876a4394359c575 214 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 174 187 2.5E-17 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L08_04615 02753d392becb811a876a4394359c575 214 ProSitePatterns PS01228 Hypothetical cof family signature 1. 3 14 - T 23-10-2018 A3L08_04615 02753d392becb811a876a4394359c575 214 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 101 179 1.4E-13 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L08_04615 02753d392becb811a876a4394359c575 214 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 84 185 7.3E-13 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L08_04615 02753d392becb811a876a4394359c575 214 TIGRFAM TIGR02253 CTE7: HAD hydrolase, TIGR02253 family 2 206 3.6E-54 T 23-10-2018 IPR011950 HAD-superfamily hydrolase, subfamily IA, CTE7 GO:0016787 Reactome: R-HSA-4085001 A3L08_04615 02753d392becb811a876a4394359c575 214 Gene3D G3DSA:3.40.50.1000 2 206 1.1E-52 T 23-10-2018 IPR023214 HAD superfamily A3L08_04615 02753d392becb811a876a4394359c575 214 Pfam PF13419 Haloacid dehalogenase-like hydrolase 4 185 3.2E-31 T 23-10-2018 A3L08_04615 02753d392becb811a876a4394359c575 214 Gene3D G3DSA:1.10.150.520 15 86 1.1E-52 T 23-10-2018 A3L08_04615 02753d392becb811a876a4394359c575 214 SUPERFAMILY SSF56784 1 211 1.84E-52 T 23-10-2018 IPR036412 HAD-like superfamily A3L08_00765 4b1aab7d045ab8da82bf8f621b5b1836 282 PIRSF PIRSF006816 1 256 7.1E-44 T 23-10-2018 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 A3L08_00765 4b1aab7d045ab8da82bf8f621b5b1836 282 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 214 250 2.0E-12 T 23-10-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain A3L08_00765 4b1aab7d045ab8da82bf8f621b5b1836 282 SUPERFAMILY SSF52343 115 249 1.19E-13 T 23-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A3L08_00765 4b1aab7d045ab8da82bf8f621b5b1836 282 Gene3D G3DSA:3.40.50.80 99 204 6.8E-15 T 23-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A3L08_00765 4b1aab7d045ab8da82bf8f621b5b1836 282 SUPERFAMILY SSF63380 3 91 1.68E-13 T 23-10-2018 IPR017938 Riboflavin synthase-like beta-barrel A3L08_00765 4b1aab7d045ab8da82bf8f621b5b1836 282 Gene3D G3DSA:2.40.30.10 1 91 3.0E-12 T 23-10-2018 A3L08_02905 c0d9ea524fd37b959cc39351a43702b4 72 Pfam PF02597 ThiS family 8 72 3.6E-11 T 23-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 A3L08_02905 c0d9ea524fd37b959cc39351a43702b4 72 SUPERFAMILY SSF54285 15 72 1.28E-10 T 23-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp A3L08_02905 c0d9ea524fd37b959cc39351a43702b4 72 Gene3D G3DSA:3.10.20.30 2 72 9.8E-13 T 23-10-2018 IPR012675 Beta-grasp domain superfamily A3L08_07940 860486427056d63696d97cde9721f565 110 SUPERFAMILY SSF57783 1 34 2.98E-6 T 23-10-2018 A3L08_07940 860486427056d63696d97cde9721f565 110 SUPERFAMILY SSF57783 47 109 1.02E-23 T 23-10-2018 A3L08_07940 860486427056d63696d97cde9721f565 110 TIGRFAM TIGR01384 TFS_arch: transcription factor S 2 110 5.6E-39 T 23-10-2018 IPR006288 Transcription factor S GO:0006355 A3L08_07940 860486427056d63696d97cde9721f565 110 ProSitePatterns PS00466 Zinc finger TFIIS-type signature. 71 106 - T 23-10-2018 IPR001222 Zinc finger, TFIIS-type GO:0003676|GO:0006351|GO:0008270 A3L08_07940 860486427056d63696d97cde9721f565 110 Gene3D G3DSA:2.20.25.10 55 110 1.3E-28 T 23-10-2018 A3L08_07940 860486427056d63696d97cde9721f565 110 ProSitePatterns PS01030 RNA polymerases M / 15 Kd subunits signature. 3 25 - T 23-10-2018 IPR019761 DNA-directed RNA polymerase M, 15kDa subunit, conserved site A3L08_07940 860486427056d63696d97cde9721f565 110 SMART SM00440 69 108 6.1E-24 T 23-10-2018 IPR001222 Zinc finger, TFIIS-type GO:0003676|GO:0006351|GO:0008270 A3L08_07940 860486427056d63696d97cde9721f565 110 Pfam PF01096 Transcription factor S-II (TFIIS) 70 107 1.3E-21 T 23-10-2018 IPR001222 Zinc finger, TFIIS-type GO:0003676|GO:0006351|GO:0008270 A3L08_07940 860486427056d63696d97cde9721f565 110 SMART SM00661 2 56 8.7E-15 T 23-10-2018 IPR001529 DNA-directed RNA polymerase, M/15kDa subunit GO:0006351 A3L08_07940 860486427056d63696d97cde9721f565 110 Pfam PF02150 RNA polymerases M/15 Kd subunit 1 34 2.2E-16 T 23-10-2018 IPR001529 DNA-directed RNA polymerase, M/15kDa subunit GO:0006351 A3L08_07940 860486427056d63696d97cde9721f565 110 PIRSF PIRSF005586 1 110 2.7E-38 T 23-10-2018 IPR012164 DNA-directed RNA polymerase subunit/transcription factor S GO:0006351 A3L08_01875 f9c9426ad7d57e7eb47c73bfc7dfb863 430 ProSitePatterns PS00164 Enolase signature. 337 350 - T 23-10-2018 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L08_01875 f9c9426ad7d57e7eb47c73bfc7dfb863 430 Pfam PF00113 Enolase, C-terminal TIM barrel domain 141 427 3.1E-130 T 23-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L08_01875 f9c9426ad7d57e7eb47c73bfc7dfb863 430 SUPERFAMILY SSF51604 139 428 4.32E-125 T 23-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily A3L08_01875 f9c9426ad7d57e7eb47c73bfc7dfb863 430 PRINTS PR00148 Enolase signature 162 175 2.2E-50 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L08_01875 f9c9426ad7d57e7eb47c73bfc7dfb863 430 PRINTS PR00148 Enolase signature 108 124 2.2E-50 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L08_01875 f9c9426ad7d57e7eb47c73bfc7dfb863 430 PRINTS PR00148 Enolase signature 366 383 2.2E-50 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L08_01875 f9c9426ad7d57e7eb47c73bfc7dfb863 430 PRINTS PR00148 Enolase signature 337 351 2.2E-50 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L08_01875 f9c9426ad7d57e7eb47c73bfc7dfb863 430 PRINTS PR00148 Enolase signature 39 53 2.2E-50 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L08_01875 f9c9426ad7d57e7eb47c73bfc7dfb863 430 PRINTS PR00148 Enolase signature 314 325 2.2E-50 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L08_01875 f9c9426ad7d57e7eb47c73bfc7dfb863 430 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 7 426 1.4E-198 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L08_01875 f9c9426ad7d57e7eb47c73bfc7dfb863 430 SMART SM01192 140 428 7.5E-205 T 23-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L08_01875 f9c9426ad7d57e7eb47c73bfc7dfb863 430 PIRSF PIRSF001400 3 427 7.3E-196 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L08_01875 f9c9426ad7d57e7eb47c73bfc7dfb863 430 Hamap MF_00318 Enolase [eno]. 5 414 45.99 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L08_01875 f9c9426ad7d57e7eb47c73bfc7dfb863 430 Gene3D G3DSA:3.30.390.10 2 128 1.0E-56 T 23-10-2018 IPR029017 Enolase-like, N-terminal A3L08_01875 f9c9426ad7d57e7eb47c73bfc7dfb863 430 Gene3D G3DSA:3.20.20.120 129 428 6.4E-133 T 23-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily A3L08_01875 f9c9426ad7d57e7eb47c73bfc7dfb863 430 SUPERFAMILY SSF54826 6 140 3.39E-58 T 23-10-2018 A3L08_01875 f9c9426ad7d57e7eb47c73bfc7dfb863 430 SMART SM01193 7 135 1.1E-95 T 23-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L08_01875 f9c9426ad7d57e7eb47c73bfc7dfb863 430 Pfam PF03952 Enolase, N-terminal domain 7 135 3.3E-60 T 23-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L08_00830 7c0ea09186e5176ada951a3776342b38 249 PIRSF PIRSF005054 1 242 2.3E-64 T 23-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 A3L08_00830 7c0ea09186e5176ada951a3776342b38 249 Gene3D G3DSA:3.30.70.1900 123 242 4.1E-38 T 23-10-2018 A3L08_00830 7c0ea09186e5176ada951a3776342b38 249 TIGRFAM TIGR01877 cas_cas6: CRISPR-associated endoribonuclease Cas6 50 237 8.1E-44 T 23-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 A3L08_00830 7c0ea09186e5176ada951a3776342b38 249 Pfam PF01881 CRISPR associated protein Cas6 95 238 2.7E-32 T 23-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 A3L08_00830 7c0ea09186e5176ada951a3776342b38 249 Gene3D G3DSA:3.30.70.1890 1 121 2.4E-44 T 23-10-2018 A3L08_05175 c4f89120b2480116c0e42408d2129cbc 456 Gene3D G3DSA:3.40.120.10 1 152 8.5E-63 T 23-10-2018 A3L08_05175 c4f89120b2480116c0e42408d2129cbc 456 TIGRFAM TIGR03990 Arch_GlmM: phosphoglucosamine mutase 3 446 9.0E-180 T 23-10-2018 IPR024086 Phosphoglucosamine mutase, archaeal type GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L08_05175 c4f89120b2480116c0e42408d2129cbc 456 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 261 370 2.8E-27 T 23-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L08_05175 c4f89120b2480116c0e42408d2129cbc 456 Gene3D G3DSA:3.40.120.10 169 358 1.9E-78 T 23-10-2018 A3L08_05175 c4f89120b2480116c0e42408d2129cbc 456 SUPERFAMILY SSF53738 261 367 1.53E-26 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L08_05175 c4f89120b2480116c0e42408d2129cbc 456 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 174 193 4.3E-18 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L08_05175 c4f89120b2480116c0e42408d2129cbc 456 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 236 251 4.3E-18 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L08_05175 c4f89120b2480116c0e42408d2129cbc 456 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 208 221 4.3E-18 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L08_05175 c4f89120b2480116c0e42408d2129cbc 456 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 94 108 4.3E-18 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L08_05175 c4f89120b2480116c0e42408d2129cbc 456 SUPERFAMILY SSF53738 155 259 5.1E-31 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L08_05175 c4f89120b2480116c0e42408d2129cbc 456 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 3 137 8.7E-47 T 23-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L08_05175 c4f89120b2480116c0e42408d2129cbc 456 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 156 256 8.0E-30 T 23-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L08_05175 c4f89120b2480116c0e42408d2129cbc 456 Gene3D G3DSA:3.30.310.50 371 455 1.9E-32 T 23-10-2018 A3L08_05175 c4f89120b2480116c0e42408d2129cbc 456 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 379 442 5.5E-13 T 23-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L08_05175 c4f89120b2480116c0e42408d2129cbc 456 SUPERFAMILY SSF53738 3 180 4.32E-47 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L08_05175 c4f89120b2480116c0e42408d2129cbc 456 SUPERFAMILY SSF55957 358 454 5.1E-24 T 23-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L08_05175 c4f89120b2480116c0e42408d2129cbc 456 Gene3D G3DSA:3.40.120.10 257 365 1.9E-78 T 23-10-2018 A3L08_02285 16dd09bd484baf5c8d5910b848e7606d 65 TIGRFAM TIGR04140 chp_AF_0576: TIGR04140 family protein 2 65 1.5E-25 T 23-10-2018 IPR026486 Uncharacterised protein AF_0576 A3L08_09100 c81a58b133ab9b2cac1c127baa223eda 353 Gene3D G3DSA:1.20.1090.10 163 352 9.0E-68 T 23-10-2018 A3L08_09100 c81a58b133ab9b2cac1c127baa223eda 353 Gene3D G3DSA:3.40.50.1970 5 162 4.0E-36 T 23-10-2018 A3L08_09100 c81a58b133ab9b2cac1c127baa223eda 353 PIRSF PIRSF000112 4 350 7.8E-67 T 23-10-2018 IPR016205 Glycerol dehydrogenase GO:0016614|GO:0046872|GO:0055114 KEGG: 00564+1.1.1.261|MetaCyc: PWY-6349 A3L08_09100 c81a58b133ab9b2cac1c127baa223eda 353 SUPERFAMILY SSF56796 9 346 1.18E-73 T 23-10-2018 A3L08_09100 c81a58b133ab9b2cac1c127baa223eda 353 Pfam PF13685 Iron-containing alcohol dehydrogenase 20 275 4.3E-73 T 23-10-2018 IPR032837 Glycerol-1-phosphate dehydrogenase KEGG: 00564+1.1.1.261|MetaCyc: PWY-6349 A3L08_09100 c81a58b133ab9b2cac1c127baa223eda 353 Hamap MF_00497_A Glycerol-1-phosphate dehydrogenase [NAD(P)+] [egsA]. 10 353 46.897 T 23-10-2018 IPR023002 Glycerol-1-phosphate dehydrogenase, archaea GO:0050492|GO:0055114 KEGG: 00564+1.1.1.261|MetaCyc: PWY-6349 A3L08_04525 ead96741c77eb611bcc191b35968835e 419 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 173 195 4.9E-30 T 23-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A3L08_04525 ead96741c77eb611bcc191b35968835e 419 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 343 354 4.9E-30 T 23-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A3L08_04525 ead96741c77eb611bcc191b35968835e 419 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 91 105 4.9E-30 T 23-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A3L08_04525 ead96741c77eb611bcc191b35968835e 419 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 215 235 4.9E-30 T 23-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A3L08_04525 ead96741c77eb611bcc191b35968835e 419 Gene3D G3DSA:3.40.50.720 182 418 1.9E-97 T 23-10-2018 A3L08_04525 ead96741c77eb611bcc191b35968835e 419 SUPERFAMILY SSF51735 182 417 2.5E-83 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L08_04525 ead96741c77eb611bcc191b35968835e 419 PIRSF PIRSF000185 1 418 3.5E-173 T 23-10-2018 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 A3L08_04525 ead96741c77eb611bcc191b35968835e 419 SUPERFAMILY SSF53223 4 184 1.28E-66 T 23-10-2018 A3L08_04525 ead96741c77eb611bcc191b35968835e 419 Gene3D G3DSA:3.40.50.10860 36 180 5.3E-66 T 23-10-2018 A3L08_04525 ead96741c77eb611bcc191b35968835e 419 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 182 415 2.0E-76 T 23-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A3L08_04525 ead96741c77eb611bcc191b35968835e 419 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 99 112 - T 23-10-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A3L08_04525 ead96741c77eb611bcc191b35968835e 419 SMART SM00839 184 415 5.2E-100 T 23-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A3L08_04525 ead96741c77eb611bcc191b35968835e 419 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 34 161 3.6E-53 T 23-10-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A3L08_08610 dbc77f2234f2524f1c780b6863690366 333 PIRSF PIRSF026760 1 333 1.6E-119 T 23-10-2018 IPR011669 Uncharacterised conserved protein UCP026760 A3L08_08610 dbc77f2234f2524f1c780b6863690366 333 Pfam PF07755 Domain of unknown function (DUF1611_C) P-loop domain 143 333 3.3E-59 T 23-10-2018 IPR035086 Domain of unknown function DUF1611, P-loop A3L08_08610 dbc77f2234f2524f1c780b6863690366 333 Pfam PF17396 Domain of unknown function (DUF1611_N) Rossmann-like domain 39 134 6.6E-30 T 23-10-2018 IPR035402 Domain of unknown function DUF1611-N, Rossmann-like domain A3L08_08610 dbc77f2234f2524f1c780b6863690366 333 Gene3D G3DSA:3.40.50.300 141 333 7.9E-57 T 23-10-2018 A3L08_08610 dbc77f2234f2524f1c780b6863690366 333 SUPERFAMILY SSF52540 3 310 1.91E-90 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_08610 dbc77f2234f2524f1c780b6863690366 333 Gene3D G3DSA:3.40.50.720 1 136 5.3E-49 T 23-10-2018 A3L08_03835 6b00f71ec0fda3ed1b0dcd601fca60db 150 SUPERFAMILY SSF54197 2 120 1.47E-37 T 23-10-2018 IPR036265 HIT-like superfamily A3L08_03835 6b00f71ec0fda3ed1b0dcd601fca60db 150 ProSitePatterns PS00892 HIT domain signature. 81 99 - T 23-10-2018 IPR019808 Histidine triad, conserved site A3L08_03835 6b00f71ec0fda3ed1b0dcd601fca60db 150 Gene3D G3DSA:3.30.428.10 1 136 2.8E-38 T 23-10-2018 IPR036265 HIT-like superfamily A3L08_03835 6b00f71ec0fda3ed1b0dcd601fca60db 150 Pfam PF01230 HIT domain 11 100 4.0E-22 T 23-10-2018 IPR001310 Histidine triad (HIT) protein A3L08_03200 a069bb206942c686501d2df66c371263 395 Pfam PF04165 Protein of unknown function (DUF401) 3 387 1.8E-65 T 23-10-2018 IPR007294 Protein of unknown function DUF401 A3L08_03200 a069bb206942c686501d2df66c371263 395 TIGRFAM TIGR00529 AF0261: integral membrane protein, TIGR00529 family 5 392 3.0E-133 T 23-10-2018 IPR005253 Conserved hypothetical protein CHP00529 A3L08_05700 fce8105b42314157caf3545827db1180 629 SUPERFAMILY SSF55261 279 404 3.11E-46 T 23-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 A3L08_05700 fce8105b42314157caf3545827db1180 629 SMART SM00845 484 624 2.8E-35 T 23-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 A3L08_05700 fce8105b42314157caf3545827db1180 629 ProDom PD609240 SUBUNIT E AMIDOTRANSFERASE 6.3.5.- LIGASE GLUTAMYL-TRNAGLN GLU-ADT BIOSYNTHESIS TRANSFERASE B 282 406 4.0E-58 T 23-10-2018 A3L08_05700 fce8105b42314157caf3545827db1180 629 Pfam PF02637 GatB domain 485 624 6.4E-28 T 23-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 A3L08_05700 fce8105b42314157caf3545827db1180 629 Pfam PF02934 GatB/GatE catalytic domain 13 444 8.7E-65 T 23-10-2018 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 A3L08_05700 fce8105b42314157caf3545827db1180 629 Gene3D G3DSA:1.10.10.410 566 624 2.5E-13 T 23-10-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal A3L08_05700 fce8105b42314157caf3545827db1180 629 SUPERFAMILY SSF89095 482 624 7.59E-27 T 23-10-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-like GO:0016884 A3L08_05700 fce8105b42314157caf3545827db1180 629 Pfam PF02938 GAD domain 299 390 1.9E-17 T 23-10-2018 IPR029351 GAD domain Reactome: R-HSA-379726 A3L08_05700 fce8105b42314157caf3545827db1180 629 SUPERFAMILY SSF55931 4 453 5.89E-98 T 23-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 A3L08_05700 fce8105b42314157caf3545827db1180 629 Hamap MF_00588 Glutamyl-tRNA(Gln) amidotransferase subunit E [gatE]. 1 629 336.172 T 23-10-2018 IPR004414 Glutamyl-tRNA(Gln) amidotransferase subunit E GO:0016884 A3L08_05700 fce8105b42314157caf3545827db1180 629 Gene3D G3DSA:3.30.1360.30 274 404 4.6E-53 T 23-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 A3L08_05700 fce8105b42314157caf3545827db1180 629 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 177 191 - T 23-10-2018 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 A3L08_05700 fce8105b42314157caf3545827db1180 629 TIGRFAM TIGR00134 gatE_arch: glutamyl-tRNA(Gln) amidotransferase, subunit E 5 627 1.7E-240 T 23-10-2018 IPR004414 Glutamyl-tRNA(Gln) amidotransferase subunit E GO:0016884 A3L08_05700 fce8105b42314157caf3545827db1180 629 Gene3D G3DSA:1.10.150.380 453 546 9.7E-24 T 23-10-2018 A3L08_06900 0422c56637938873ab076ae2bc392904 428 Hamap MF_00089 Phosphomethylpyrimidine synthase [thiC]. 1 425 87.563 T 23-10-2018 IPR037509 Phosphomethylpyrimidine synthase GO:0009228|GO:0016830 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 A3L08_06900 0422c56637938873ab076ae2bc392904 428 TIGRFAM TIGR00190 thiC: phosphomethylpyrimidine synthase 1 422 1.7E-185 T 23-10-2018 IPR002817 Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 A3L08_06900 0422c56637938873ab076ae2bc392904 428 Pfam PF01964 Radical SAM ThiC family 2 420 1.9E-181 T 23-10-2018 IPR002817 Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 A3L08_06900 0422c56637938873ab076ae2bc392904 428 Gene3D G3DSA:3.20.20.540 44 362 1.5E-137 T 23-10-2018 IPR038521 ThiC/Bza superfamily KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 A3L08_06265 5e036687e5733c788ef4b8a0b6f6dd9a 428 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 209 295 8.5E-24 T 23-10-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A3L08_06265 5e036687e5733c788ef4b8a0b6f6dd9a 428 SMART SM00984 322 413 3.0E-34 T 23-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A3L08_06265 5e036687e5733c788ef4b8a0b6f6dd9a 428 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 11 191 2.6E-52 T 23-10-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A3L08_06265 5e036687e5733c788ef4b8a0b6f6dd9a 428 PIRSF PIRSF500136 2 425 1.3E-144 T 23-10-2018 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 A3L08_06265 5e036687e5733c788ef4b8a0b6f6dd9a 428 SUPERFAMILY SSF51735 12 201 2.74E-51 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L08_06265 5e036687e5733c788ef4b8a0b6f6dd9a 428 Gene3D G3DSA:3.40.50.720 240 428 3.7E-68 T 23-10-2018 A3L08_06265 5e036687e5733c788ef4b8a0b6f6dd9a 428 SUPERFAMILY SSF52413 312 412 8.24E-25 T 23-10-2018 IPR036220 UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily Reactome: R-HSA-173599 A3L08_06265 5e036687e5733c788ef4b8a0b6f6dd9a 428 SUPERFAMILY SSF48179 209 298 1.09E-26 T 23-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 A3L08_06265 5e036687e5733c788ef4b8a0b6f6dd9a 428 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 322 412 3.2E-24 T 23-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A3L08_06265 5e036687e5733c788ef4b8a0b6f6dd9a 428 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 11 408 3.4E-127 T 23-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 A3L08_06265 5e036687e5733c788ef4b8a0b6f6dd9a 428 Gene3D G3DSA:3.40.50.720 11 206 1.6E-74 T 23-10-2018 A3L08_06265 5e036687e5733c788ef4b8a0b6f6dd9a 428 PIRSF PIRSF000124 10 416 7.7E-82 T 23-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 A3L08_02875 8b0b3f5a31e97ba9435faf91b592eae3 1067 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 223 246 5.3E-30 T 23-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A3L08_02875 8b0b3f5a31e97ba9435faf91b592eae3 1067 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 42 53 5.3E-30 T 23-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A3L08_02875 8b0b3f5a31e97ba9435faf91b592eae3 1067 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 584 593 5.3E-30 T 23-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A3L08_02875 8b0b3f5a31e97ba9435faf91b592eae3 1067 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 545 558 5.3E-30 T 23-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A3L08_02875 8b0b3f5a31e97ba9435faf91b592eae3 1067 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 399 414 5.3E-30 T 23-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A3L08_02875 8b0b3f5a31e97ba9435faf91b592eae3 1067 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 49 60 - T 23-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L08_02875 8b0b3f5a31e97ba9435faf91b592eae3 1067 Hamap MF_02003 Isoleucine--tRNA ligase [ileS]. 3 1066 13.769 T 23-10-2018 IPR023586 Isoleucine-tRNA ligase, type 2 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A3L08_02875 8b0b3f5a31e97ba9435faf91b592eae3 1067 SUPERFAMILY SSF52374 2 674 7.59E-134 T 23-10-2018 A3L08_02875 8b0b3f5a31e97ba9435faf91b592eae3 1067 SUPERFAMILY SSF50677 201 401 3.66E-56 T 23-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 A3L08_02875 8b0b3f5a31e97ba9435faf91b592eae3 1067 Gene3D G3DSA:3.90.740.10 199 405 9.8E-231 T 23-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 A3L08_02875 8b0b3f5a31e97ba9435faf91b592eae3 1067 SUPERFAMILY SSF47323 983 1051 5.3E-6 T 23-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L08_02875 8b0b3f5a31e97ba9435faf91b592eae3 1067 Pfam PF08264 Anticodon-binding domain of tRNA 711 862 2.4E-37 T 23-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 A3L08_02875 8b0b3f5a31e97ba9435faf91b592eae3 1067 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 21 663 5.5E-190 T 23-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L08_02875 8b0b3f5a31e97ba9435faf91b592eae3 1067 Gene3D G3DSA:1.10.730.10 669 853 3.7E-55 T 23-10-2018 A3L08_02875 8b0b3f5a31e97ba9435faf91b592eae3 1067 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 10 876 0.0 T 23-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A3L08_02875 8b0b3f5a31e97ba9435faf91b592eae3 1067 SUPERFAMILY SSF47323 676 912 2.43E-61 T 23-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L08_02875 8b0b3f5a31e97ba9435faf91b592eae3 1067 Gene3D G3DSA:3.40.50.620 16 651 9.8E-231 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L08_04265 f1d68ed3467dfcfce00db4df14a59155 57 SUPERFAMILY SSF63562 3 55 5.1E-20 T 23-10-2018 IPR036161 RPB6/omega subunit-like superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A3L08_04265 f1d68ed3467dfcfce00db4df14a59155 57 Gene3D G3DSA:3.90.940.50 1 57 1.1E-27 T 23-10-2018 A3L08_04265 f1d68ed3467dfcfce00db4df14a59155 57 ProSitePatterns PS01111 RNA polymerases K / 14 to 18 Kd subunits signature. 5 19 - T 23-10-2018 IPR020708 DNA-directed RNA polymerase, 14-18kDa subunit, conserved site GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A3L08_04265 f1d68ed3467dfcfce00db4df14a59155 57 Hamap MF_00192 DNA-directed RNA polymerase subunit K [rpoK]. 2 57 21.785 T 23-10-2018 IPR006111 Archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A3L08_04265 f1d68ed3467dfcfce00db4df14a59155 57 Pfam PF01192 RNA polymerase Rpb6 5 51 4.9E-11 T 23-10-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A3L08_04265 f1d68ed3467dfcfce00db4df14a59155 57 PIRSF PIRSF000778 1 57 4.2E-22 T 23-10-2018 IPR006111 Archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A3L08_06960 e111dd9784cdb4d79f93c6cec35fb23f 679 Gene3D G3DSA:3.10.105.10 300 547 5.5E-173 T 23-10-2018 A3L08_06960 e111dd9784cdb4d79f93c6cec35fb23f 679 Gene3D G3DSA:3.40.190.10 33 567 5.5E-173 T 23-10-2018 A3L08_06960 e111dd9784cdb4d79f93c6cec35fb23f 679 SUPERFAMILY SSF53850 39 569 1.56E-98 T 23-10-2018 A3L08_06960 e111dd9784cdb4d79f93c6cec35fb23f 679 Gene3D G3DSA:3.90.76.10 70 251 5.5E-173 T 23-10-2018 A3L08_06960 e111dd9784cdb4d79f93c6cec35fb23f 679 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 93 476 2.6E-70 T 23-10-2018 IPR000914 Solute-binding protein family 5 domain A3L08_02405 1f6ae66cfb49d82342081cae113cb848 653 Pfam PF03065 Glycosyl hydrolase family 57 5 288 1.4E-65 T 23-10-2018 IPR004300 Glycoside hydrolase family 57, N-terminal domain GO:0003824|GO:0005975 A3L08_02405 1f6ae66cfb49d82342081cae113cb848 653 SUPERFAMILY SSF88713 3 307 8.9E-68 T 23-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 A3L08_02405 1f6ae66cfb49d82342081cae113cb848 653 Pfam PF09094 Domain of unknown function (DUF1925) 309 380 3.3E-36 T 23-10-2018 IPR015178 Alpha-amylase/4-alpha-glucanotransferase, central domain A3L08_02405 1f6ae66cfb49d82342081cae113cb848 653 SUPERFAMILY SSF88688 309 381 1.05E-36 T 23-10-2018 IPR028995 Glycoside hydrolase families 57/38, central domain superfamily A3L08_02405 1f6ae66cfb49d82342081cae113cb848 653 Gene3D G3DSA:2.70.98.10 386 652 1.8E-86 T 23-10-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 A3L08_02405 1f6ae66cfb49d82342081cae113cb848 653 Gene3D G3DSA:3.20.110.20 1 379 9.5E-176 T 23-10-2018 A3L08_02405 1f6ae66cfb49d82342081cae113cb848 653 ProDom PD014405 HYDROLASE METABOLISM CARBOHYDRATE GLYCOSIDASE ALPHA-AMYLASE TRANSFERASE 4-ALPHA-GLUCANOTRANSFERASE GLYCOSYLTRANSFERASE FAMILY DIRECT 317 382 5.0E-30 T 23-10-2018 IPR015178 Alpha-amylase/4-alpha-glucanotransferase, central domain A3L08_02405 1f6ae66cfb49d82342081cae113cb848 653 SUPERFAMILY SSF74650 386 651 5.02E-97 T 23-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 A3L08_02405 1f6ae66cfb49d82342081cae113cb848 653 Pfam PF09095 Domain of unknown function (DUF1926) 390 648 1.4E-78 T 23-10-2018 IPR015179 Alpha-amylase/4-alpha-glucanotransferase, C-terminal GO:0003824|GO:0005975|GO:0030246 A3L08_07030 5a19a8d407dd49ce12371f607928b455 349 Gene3D G3DSA:3.90.550.10 28 241 2.8E-47 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L08_07030 5a19a8d407dd49ce12371f607928b455 349 SUPERFAMILY SSF53448 36 300 1.3E-56 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L08_07030 5a19a8d407dd49ce12371f607928b455 349 Pfam PF00535 Glycosyl transferase family 2 40 200 1.8E-36 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A3L08_08085 ede1710b191ae069d0f9be132ef4651d 125 Pfam PF03625 Domain of unknown function DUF302 49 88 1.0E-5 T 23-10-2018 IPR005180 Domain of unknown function DUF302 A3L08_08085 ede1710b191ae069d0f9be132ef4651d 125 Gene3D G3DSA:3.30.310.70 7 124 6.4E-9 T 23-10-2018 IPR035923 TT1751-like domain superfamily A3L08_08085 ede1710b191ae069d0f9be132ef4651d 125 SUPERFAMILY SSF103247 14 124 4.05E-14 T 23-10-2018 IPR035923 TT1751-like domain superfamily A3L08_04930 2926f4670b1a1b2b7345384aa435deb2 255 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 17 82 1.0E-11 T 23-10-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 A3L08_04930 2926f4670b1a1b2b7345384aa435deb2 255 Gene3D G3DSA:3.20.20.190 7 240 1.4E-34 T 23-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 A3L08_04930 2926f4670b1a1b2b7345384aa435deb2 255 SUPERFAMILY SSF51695 12 230 4.71E-32 T 23-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 A3L08_09345 b6126c32df931ebde53ad00af5dad89f 184 TIGRFAM TIGR00172 maf: septum formation protein Maf 2 175 4.1E-52 T 23-10-2018 IPR003697 Maf-like protein GO:0047429 A3L08_09345 b6126c32df931ebde53ad00af5dad89f 184 Pfam PF02545 Maf-like protein 2 175 4.7E-59 T 23-10-2018 IPR003697 Maf-like protein GO:0047429 A3L08_09345 b6126c32df931ebde53ad00af5dad89f 184 PIRSF PIRSF006305 1 183 2.5E-59 T 23-10-2018 IPR003697 Maf-like protein GO:0047429 A3L08_09345 b6126c32df931ebde53ad00af5dad89f 184 Hamap MF_00528 Septum formation protein Maf [maf]. 1 183 32.08 T 23-10-2018 IPR003697 Maf-like protein GO:0047429 A3L08_09345 b6126c32df931ebde53ad00af5dad89f 184 Gene3D G3DSA:3.90.950.10 1 180 9.5E-67 T 23-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like A3L08_09345 b6126c32df931ebde53ad00af5dad89f 184 SUPERFAMILY SSF52972 1 175 5.82E-60 T 23-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like A3L08_09705 178615f72bd0bd3aa99f273ccfb2ef59 177 SUPERFAMILY SSF75217 1 175 6.28E-71 T 23-10-2018 IPR029028 Alpha/beta knot methyltransferases A3L08_09705 178615f72bd0bd3aa99f273ccfb2ef59 177 Pfam PF01994 tRNA ribose 2'-O-methyltransferase, aTrm56 54 175 2.1E-52 T 23-10-2018 IPR002845 tRNA ribose 2'-O-methyltransferase, aTrm56 GO:0002128|GO:0005737|GO:0008175 A3L08_09705 178615f72bd0bd3aa99f273ccfb2ef59 177 Hamap MF_00077 tRNA (cytidine(56)-2'-O)-methyltransferase. 1 177 44.85 T 23-10-2018 IPR002845 tRNA ribose 2'-O-methyltransferase, aTrm56 GO:0002128|GO:0005737|GO:0008175 A3L08_09705 178615f72bd0bd3aa99f273ccfb2ef59 177 PIRSF PIRSF016123 1 177 5.2E-87 T 23-10-2018 IPR002845 tRNA ribose 2'-O-methyltransferase, aTrm56 GO:0002128|GO:0005737|GO:0008175 A3L08_09705 178615f72bd0bd3aa99f273ccfb2ef59 177 Gene3D G3DSA:3.40.1280.10 1 177 3.3E-79 T 23-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal A3L08_09705 178615f72bd0bd3aa99f273ccfb2ef59 177 ProDom PD016584 UPF0106 MK0803 MM0086 METAL MA3241 UNCHARACTERIZED DOMAIN TA0931 APE2006 ST0333 54 177 1.0E-56 T 23-10-2018 IPR002845 tRNA ribose 2'-O-methyltransferase, aTrm56 GO:0002128|GO:0005737|GO:0008175 A3L08_02155 cfd75c80a29bdcc1056eddb4dce455eb 415 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 232 406 1.3E-9 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A3L08_02155 cfd75c80a29bdcc1056eddb4dce455eb 415 SUPERFAMILY SSF161098 209 404 1.26E-13 T 23-10-2018 IPR035906 MetI-like superfamily A3L08_02155 cfd75c80a29bdcc1056eddb4dce455eb 415 Gene3D G3DSA:1.10.3720.10 203 414 5.7E-11 T 23-10-2018 IPR035906 MetI-like superfamily A3L08_04320 3f3b1ec406d0e9b66c539e9d087d01bf 238 Pfam PF01381 Helix-turn-helix 17 61 1.7E-5 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A3L08_04320 3f3b1ec406d0e9b66c539e9d087d01bf 238 Gene3D G3DSA:3.40.50.2020 65 238 4.3E-39 T 23-10-2018 A3L08_04320 3f3b1ec406d0e9b66c539e9d087d01bf 238 SUPERFAMILY SSF47413 16 62 8.28E-5 T 23-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A3L08_04320 3f3b1ec406d0e9b66c539e9d087d01bf 238 Pfam PF00156 Phosphoribosyl transferase domain 99 214 4.6E-12 T 23-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 A3L08_04320 3f3b1ec406d0e9b66c539e9d087d01bf 238 SUPERFAMILY SSF53271 75 237 5.64E-35 T 23-10-2018 IPR029057 Phosphoribosyltransferase-like A3L08_03915 689e465e09a13835f39b583a43c5956b 522 Pfam PF01039 Carboxyl transferase domain 28 520 5.0E-203 T 23-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 A3L08_03915 689e465e09a13835f39b583a43c5956b 522 SUPERFAMILY SSF52096 244 522 6.43E-93 T 23-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A3L08_03915 689e465e09a13835f39b583a43c5956b 522 Gene3D G3DSA:3.90.226.10 1 260 3.3E-98 T 23-10-2018 A3L08_03915 689e465e09a13835f39b583a43c5956b 522 Gene3D G3DSA:3.90.226.10 262 522 4.9E-96 T 23-10-2018 A3L08_03915 689e465e09a13835f39b583a43c5956b 522 SUPERFAMILY SSF52096 3 257 2.34E-79 T 23-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A3L08_03655 cb53f5aa46821ebf0daec1ea23120dbb 445 PIRSF PIRSF005353 1 442 1.8E-168 T 23-10-2018 IPR026033 Purine permease PbuG-like A3L08_03655 cb53f5aa46821ebf0daec1ea23120dbb 445 Pfam PF00860 Permease family 20 400 1.8E-45 T 23-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 A3L08_06560 1afb544a8f41c2663f8280ab3b370b29 229 Pfam PF04039 Domain related to MnhB subunit of Na+/H+ antiporter 91 215 2.4E-20 T 23-10-2018 IPR007182 Na+/H+ antiporter MnhB subunit-related protein A3L08_04740 7cea6ab6aa0655a9f4b8046f8ad15a75 238 SUPERFAMILY SSF46785 1 82 2.2E-14 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L08_04740 7cea6ab6aa0655a9f4b8046f8ad15a75 238 Gene3D G3DSA:1.10.10.10 4 79 3.3E-20 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L08_04740 7cea6ab6aa0655a9f4b8046f8ad15a75 238 SUPERFAMILY SSF46785 155 206 3.56E-5 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L08_04740 7cea6ab6aa0655a9f4b8046f8ad15a75 238 SMART SM00418 7 88 1.0E-9 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L08_04740 7cea6ab6aa0655a9f4b8046f8ad15a75 238 Gene3D G3DSA:1.10.10.10 166 234 1.9E-35 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L08_04740 7cea6ab6aa0655a9f4b8046f8ad15a75 238 Pfam PF12840 Helix-turn-helix domain 7 61 2.3E-8 T 23-10-2018 A3L08_03665 1f993923fc355d82d4c98cf9414db6fc 541 SUPERFAMILY SSF161098 288 536 3.64E-54 T 23-10-2018 IPR035906 MetI-like superfamily A3L08_03665 1f993923fc355d82d4c98cf9414db6fc 541 Gene3D G3DSA:1.10.3720.10 286 540 5.3E-54 T 23-10-2018 IPR035906 MetI-like superfamily A3L08_03665 1f993923fc355d82d4c98cf9414db6fc 541 Gene3D G3DSA:1.10.3720.10 5 263 7.2E-62 T 23-10-2018 IPR035906 MetI-like superfamily A3L08_03665 1f993923fc355d82d4c98cf9414db6fc 541 SUPERFAMILY SSF161098 7 258 4.45E-53 T 23-10-2018 IPR035906 MetI-like superfamily A3L08_03665 1f993923fc355d82d4c98cf9414db6fc 541 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 359 533 2.2E-13 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A3L08_03665 1f993923fc355d82d4c98cf9414db6fc 541 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 74 256 1.3E-16 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A3L08_01480 e59429aeedaaa4a37ef415b48d79dc45 141 Pfam PF01037 Lrp/AsnC ligand binding domain 68 138 1.2E-14 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A3L08_01480 e59429aeedaaa4a37ef415b48d79dc45 141 Pfam PF13412 Winged helix-turn-helix DNA-binding 2 49 1.4E-14 T 23-10-2018 A3L08_01480 e59429aeedaaa4a37ef415b48d79dc45 141 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 18 29 4.9E-16 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L08_01480 e59429aeedaaa4a37ef415b48d79dc45 141 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 2 18 4.9E-16 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L08_01480 e59429aeedaaa4a37ef415b48d79dc45 141 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 29 48 4.9E-16 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L08_01480 e59429aeedaaa4a37ef415b48d79dc45 141 SUPERFAMILY SSF46785 1 62 1.82E-18 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L08_01480 e59429aeedaaa4a37ef415b48d79dc45 141 Gene3D G3DSA:3.30.70.920 65 141 2.2E-20 T 23-10-2018 A3L08_01480 e59429aeedaaa4a37ef415b48d79dc45 141 Gene3D G3DSA:1.10.10.10 1 52 6.9E-22 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L08_01480 e59429aeedaaa4a37ef415b48d79dc45 141 SUPERFAMILY SSF54909 62 141 1.14E-16 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel A3L08_01480 e59429aeedaaa4a37ef415b48d79dc45 141 SMART SM00344 2 108 5.5E-49 T 23-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A3L08_01480 e59429aeedaaa4a37ef415b48d79dc45 141 ProSitePatterns PS00519 AsnC-type HTH domain signature. 20 46 - T 23-10-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site A3L08_03440 7bee7eeff8cf378c9853819bd2fd8b4d 352 SUPERFAMILY SSF53448 2 227 1.0E-45 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L08_03440 7bee7eeff8cf378c9853819bd2fd8b4d 352 Pfam PF04138 GtrA-like protein 236 351 1.2E-26 T 23-10-2018 IPR007267 GtrA-like protein GO:0000271|GO:0016021 A3L08_03440 7bee7eeff8cf378c9853819bd2fd8b4d 352 Pfam PF00535 Glycosyl transferase family 2 4 167 7.4E-38 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A3L08_03440 7bee7eeff8cf378c9853819bd2fd8b4d 352 Gene3D G3DSA:3.90.550.10 1 239 7.5E-54 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L08_02790 aac248575d099b242757b6704887ce47 456 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 149 245 6.7E-26 T 23-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L08_02790 aac248575d099b242757b6704887ce47 456 Gene3D G3DSA:3.30.310.50 357 453 1.4E-17 T 23-10-2018 A3L08_02790 aac248575d099b242757b6704887ce47 456 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 2 130 8.6E-40 T 23-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L08_02790 aac248575d099b242757b6704887ce47 456 TIGRFAM TIGR03990 Arch_GlmM: phosphoglucosamine mutase 1 440 3.4E-148 T 23-10-2018 IPR024086 Phosphoglucosamine mutase, archaeal type GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L08_02790 aac248575d099b242757b6704887ce47 456 SUPERFAMILY SSF55957 345 449 6.41E-20 T 23-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L08_02790 aac248575d099b242757b6704887ce47 456 SUPERFAMILY SSF53738 250 351 1.06E-12 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L08_02790 aac248575d099b242757b6704887ce47 456 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 163 182 3.5E-16 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L08_02790 aac248575d099b242757b6704887ce47 456 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 225 240 3.5E-16 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L08_02790 aac248575d099b242757b6704887ce47 456 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 197 210 3.5E-16 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L08_02790 aac248575d099b242757b6704887ce47 456 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 87 101 3.5E-16 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L08_02790 aac248575d099b242757b6704887ce47 456 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 250 356 5.2E-7 T 23-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L08_02790 aac248575d099b242757b6704887ce47 456 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 371 437 5.2E-11 T 23-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L08_02790 aac248575d099b242757b6704887ce47 456 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 88 97 - T 23-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L08_02790 aac248575d099b242757b6704887ce47 456 Gene3D G3DSA:3.40.120.10 162 344 2.6E-47 T 23-10-2018 A3L08_02790 aac248575d099b242757b6704887ce47 456 Gene3D G3DSA:3.40.120.10 246 349 2.6E-47 T 23-10-2018 A3L08_02790 aac248575d099b242757b6704887ce47 456 SUPERFAMILY SSF53738 148 247 4.32E-27 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L08_02790 aac248575d099b242757b6704887ce47 456 SUPERFAMILY SSF53738 2 169 7.85E-42 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A3L08_02790 aac248575d099b242757b6704887ce47 456 Gene3D G3DSA:3.40.120.10 1 144 2.3E-47 T 23-10-2018 A3L08_09335 271c6075ee7f709ef939b0cb625ff3c9 237 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 208 224 - T 23-10-2018 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 A3L08_09335 271c6075ee7f709ef939b0cb625ff3c9 237 Pfam PF00633 Helix-hairpin-helix motif 119 148 3.0E-7 T 23-10-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 A3L08_09335 271c6075ee7f709ef939b0cb625ff3c9 237 ProSitePatterns PS01155 Endonuclease III family signature. 122 151 - T 23-10-2018 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 A3L08_09335 271c6075ee7f709ef939b0cb625ff3c9 237 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 52 189 9.0E-17 T 23-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 A3L08_09335 271c6075ee7f709ef939b0cb625ff3c9 237 PIRSF PIRSF001435 18 230 6.1E-42 T 23-10-2018 A3L08_09335 271c6075ee7f709ef939b0cb625ff3c9 237 SUPERFAMILY SSF48150 23 227 2.2E-62 T 23-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 A3L08_09335 271c6075ee7f709ef939b0cb625ff3c9 237 Gene3D G3DSA:1.10.340.30 39 152 1.4E-64 T 23-10-2018 A3L08_09335 271c6075ee7f709ef939b0cb625ff3c9 237 SMART SM00525 207 227 7.1E-7 T 23-10-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 A3L08_09335 271c6075ee7f709ef939b0cb625ff3c9 237 Gene3D G3DSA:1.10.1670.10 34 224 1.4E-64 T 23-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 A3L08_09335 271c6075ee7f709ef939b0cb625ff3c9 237 SMART SM00478 56 206 7.1E-56 T 23-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 A3L08_09335 271c6075ee7f709ef939b0cb625ff3c9 237 Hamap MF_00942 Endonuclease III [nth]. 20 230 33.847 T 23-10-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 A3L08_04215 4462722ad614565c41a493bd830e7b5d 149 Gene3D G3DSA:4.10.910.10 88 138 2.2E-20 T 23-10-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_04215 4462722ad614565c41a493bd830e7b5d 149 Pfam PF00416 Ribosomal protein S13/S18 10 137 1.2E-39 T 23-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_04215 4462722ad614565c41a493bd830e7b5d 149 SUPERFAMILY SSF46946 9 148 4.21E-34 T 23-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 A3L08_04215 4462722ad614565c41a493bd830e7b5d 149 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 8 148 24.514 T 23-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_04215 4462722ad614565c41a493bd830e7b5d 149 TIGRFAM TIGR03629 uS13_arch: ribosomal protein uS13 4 148 2.7E-60 T 23-10-2018 IPR019977 Ribosomal protein S13, archaeal GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L08_04215 4462722ad614565c41a493bd830e7b5d 149 Gene3D G3DSA:1.10.8.50 1 76 3.4E-26 T 23-10-2018 A3L08_04215 4462722ad614565c41a493bd830e7b5d 149 PIRSF PIRSF002134 2 149 6.7E-41 T 23-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_09030 5eea02a2537e5e03cd2497b6b28b96f6 217 SUPERFAMILY SSF89550 5 213 1.15E-39 T 23-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 A3L08_09030 5eea02a2537e5e03cd2497b6b28b96f6 217 SMART SM00481 5 77 2.8E-11 T 23-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal A3L08_09030 5eea02a2537e5e03cd2497b6b28b96f6 217 Pfam PF02811 PHP domain 6 80 3.1E-9 T 23-10-2018 IPR004013 PHP domain GO:0003824 A3L08_09030 5eea02a2537e5e03cd2497b6b28b96f6 217 Gene3D G3DSA:3.20.20.140 2 216 3.8E-47 T 23-10-2018 A3L08_08475 3cf728275f9043c4dcc6b66dfd8e3351 296 Gene3D G3DSA:3.30.70.20 52 133 6.7E-15 T 23-10-2018 A3L08_08475 3cf728275f9043c4dcc6b66dfd8e3351 296 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 71 82 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L08_08475 3cf728275f9043c4dcc6b66dfd8e3351 296 SUPERFAMILY SSF54862 53 121 9.07E-18 T 23-10-2018 A3L08_08475 3cf728275f9043c4dcc6b66dfd8e3351 296 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 101 112 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L08_08475 3cf728275f9043c4dcc6b66dfd8e3351 296 Pfam PF14697 4Fe-4S dicluster domain 64 118 7.7E-12 T 23-10-2018 A3L08_08475 3cf728275f9043c4dcc6b66dfd8e3351 296 SUPERFAMILY SSF52540 2 294 1.65E-36 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_08475 3cf728275f9043c4dcc6b66dfd8e3351 296 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 3 264 6.5E-22 T 23-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain A3L08_09185 5e66a1816a2239a9549d56b79ade5022 503 Gene3D G3DSA:3.40.1030.10 152 412 2.9E-101 T 23-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 A3L08_09185 5e66a1816a2239a9549d56b79ade5022 503 SMART SM00941 424 491 5.6E-26 T 23-10-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A3L08_09185 5e66a1816a2239a9549d56b79ade5022 503 TIGRFAM TIGR03327 AMP_phos: AMP phosphorylase 3 500 7.5E-245 T 23-10-2018 IPR017713 AMP phosphorylase GO:0009032|GO:0046125 MetaCyc: PWY-5532 A3L08_09185 5e66a1816a2239a9549d56b79ade5022 503 ProSitePatterns PS00647 Thymidine and pyrimidine-nucleoside phosphorylases signature. 193 208 - T 23-10-2018 IPR017872 Pyrimidine-nucleoside phosphorylase, conserved site GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A3L08_09185 5e66a1816a2239a9549d56b79ade5022 503 SUPERFAMILY SSF54680 412 495 3.14E-19 T 23-10-2018 IPR036566 Pyrimidine nucleoside phosphorylase-like, C-terminal domain superfamily GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A3L08_09185 5e66a1816a2239a9549d56b79ade5022 503 Gene3D G3DSA:3.90.1170.30 413 493 1.1E-29 T 23-10-2018 IPR036566 Pyrimidine nucleoside phosphorylase-like, C-terminal domain superfamily GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A3L08_09185 5e66a1816a2239a9549d56b79ade5022 503 Hamap MF_02132 AMP phosphorylase. 1 503 46.797 T 23-10-2018 IPR017713 AMP phosphorylase GO:0009032|GO:0046125 MetaCyc: PWY-5532 A3L08_09185 5e66a1816a2239a9549d56b79ade5022 503 Pfam PF00591 Glycosyl transferase family, a/b domain 158 386 1.3E-14 T 23-10-2018 IPR000312 Glycosyl transferase, family 3 GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A3L08_09185 5e66a1816a2239a9549d56b79ade5022 503 TIGRFAM TIGR02645 ARCH_P_rylase: putative thymidine phosphorylase 4 494 1.0E-229 T 23-10-2018 IPR013466 Thymidine phosphorylase/AMP phosphorylase GO:0016763 A3L08_09185 5e66a1816a2239a9549d56b79ade5022 503 Gene3D G3DSA:1.20.970.10 84 151 2.7E-24 T 23-10-2018 A3L08_09185 5e66a1816a2239a9549d56b79ade5022 503 Pfam PF07831 Pyrimidine nucleoside phosphorylase C-terminal domain 424 485 8.9E-16 T 23-10-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A3L08_09185 5e66a1816a2239a9549d56b79ade5022 503 SUPERFAMILY SSF52418 155 405 4.58E-69 T 23-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 A3L08_09185 5e66a1816a2239a9549d56b79ade5022 503 Pfam PF02885 Glycosyl transferase family, helical bundle domain 89 150 3.0E-15 T 23-10-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 A3L08_09185 5e66a1816a2239a9549d56b79ade5022 503 PIRSF PIRSF000478 84 502 4.5E-125 T 23-10-2018 IPR000053 Thymidine/pyrimidine-nucleoside phosphorylase GO:0004645|GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A3L08_09185 5e66a1816a2239a9549d56b79ade5022 503 Gene3D G3DSA:2.40.40.20 1 83 5.9E-36 T 23-10-2018 A3L08_09185 5e66a1816a2239a9549d56b79ade5022 503 SUPERFAMILY SSF47648 86 153 7.46E-17 T 23-10-2018 IPR036320 Glycosyl transferase family 3, N-terminal domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 A3L08_06005 3f930649b6514b94236042de2aff101d 103 Pfam PF11419 Protein of unknown function (DUF3194) 12 94 3.3E-26 T 23-10-2018 IPR024502 Protein of unknown function DUF3194 A3L08_06005 3f930649b6514b94236042de2aff101d 103 Gene3D G3DSA:3.30.300.100 1 103 1.1E-36 T 23-10-2018 IPR035954 MTH677-like superfamily A3L08_06005 3f930649b6514b94236042de2aff101d 103 SUPERFAMILY SSF110783 12 99 3.27E-5 T 23-10-2018 IPR035954 MTH677-like superfamily A3L08_02825 bbc98cd33cb9e9ae44dbc2e3a50eced5 630 SUPERFAMILY SSF51445 194 586 1.48E-97 T 23-10-2018 IPR017853 Glycoside hydrolase superfamily A3L08_02825 bbc98cd33cb9e9ae44dbc2e3a50eced5 630 Pfam PF00128 Alpha amylase, catalytic domain 238 546 6.7E-65 T 23-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 A3L08_02825 bbc98cd33cb9e9ae44dbc2e3a50eced5 630 SMART SM00642 213 579 5.4E-101 T 23-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 A3L08_02825 bbc98cd33cb9e9ae44dbc2e3a50eced5 630 Gene3D G3DSA:2.60.40.10 4 105 3.5E-16 T 23-10-2018 IPR013783 Immunoglobulin-like fold A3L08_02825 bbc98cd33cb9e9ae44dbc2e3a50eced5 630 Gene3D G3DSA:3.20.20.80 201 585 5.0E-150 T 23-10-2018 A3L08_02825 bbc98cd33cb9e9ae44dbc2e3a50eced5 630 Pfam PF02903 Alpha amylase, N-terminal ig-like domain 111 194 1.8E-5 T 23-10-2018 IPR004185 Glycoside hydrolase, family 13, N-terminal Ig-like domain GO:0004553|GO:0005975 A3L08_02825 bbc98cd33cb9e9ae44dbc2e3a50eced5 630 SUPERFAMILY SSF81296 30 87 3.03E-9 T 23-10-2018 IPR014756 Immunoglobulin E-set A3L08_02825 bbc98cd33cb9e9ae44dbc2e3a50eced5 630 SUPERFAMILY SSF81296 110 200 3.64E-9 T 23-10-2018 IPR014756 Immunoglobulin E-set A3L08_02825 bbc98cd33cb9e9ae44dbc2e3a50eced5 630 Gene3D G3DSA:2.60.40.10 106 199 6.4E-23 T 23-10-2018 IPR013783 Immunoglobulin-like fold A3L08_04030 d34a0f2dc4e5355ff7cd78d5156cc0b2 182 Hamap MF_00448 50S ribosomal protein L10e [rpl10e]. 1 174 36.661 T 23-10-2018 IPR022981 Ribosomal protein L10e, archaea A3L08_04030 d34a0f2dc4e5355ff7cd78d5156cc0b2 182 Gene3D G3DSA:3.90.1170.10 1 180 4.6E-64 T 23-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 A3L08_04030 d34a0f2dc4e5355ff7cd78d5156cc0b2 182 Pfam PF00252 Ribosomal protein L16p/L10e 14 159 8.1E-33 T 23-10-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 A3L08_04030 d34a0f2dc4e5355ff7cd78d5156cc0b2 182 PIRSF PIRSF005590 1 180 3.3E-69 T 23-10-2018 IPR001197 Ribosomal protein L10e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_04030 d34a0f2dc4e5355ff7cd78d5156cc0b2 182 SUPERFAMILY SSF54686 4 168 6.15E-56 T 23-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 A3L08_04030 d34a0f2dc4e5355ff7cd78d5156cc0b2 182 ProSitePatterns PS01257 Ribosomal protein L10e signature. 105 126 - T 23-10-2018 IPR018255 Ribosomal protein L10e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_04555 6960d56fbcc8f0a6fd50cf36bef155aa 227 SUPERFAMILY SSF100950 2 150 2.74E-46 T 23-10-2018 IPR037171 NagB/RpiA transferase-like A3L08_04555 6960d56fbcc8f0a6fd50cf36bef155aa 227 Hamap MF_00170 Ribose-5-phosphate isomerase A [rpiA]. 1 225 36.713 T 23-10-2018 IPR020672 Ribose-5-phosphate isomerase, type A, subgroup GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 A3L08_04555 6960d56fbcc8f0a6fd50cf36bef155aa 227 Gene3D G3DSA:3.40.50.1360 5 221 3.2E-90 T 23-10-2018 A3L08_04555 6960d56fbcc8f0a6fd50cf36bef155aa 227 Gene3D G3DSA:3.30.70.260 127 205 3.2E-90 T 23-10-2018 A3L08_04555 6960d56fbcc8f0a6fd50cf36bef155aa 227 TIGRFAM TIGR00021 rpiA: ribose 5-phosphate isomerase A 4 223 1.5E-83 T 23-10-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 A3L08_04555 6960d56fbcc8f0a6fd50cf36bef155aa 227 Pfam PF06026 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) 51 221 7.9E-67 T 23-10-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 A3L08_04555 6960d56fbcc8f0a6fd50cf36bef155aa 227 SUPERFAMILY SSF75445 131 207 2.62E-25 T 23-10-2018 A3L08_03850 9cbdd7a490c833acfb0d2cefc51531dd 236 Gene3D G3DSA:3.30.70.240 163 235 7.5E-29 T 23-10-2018 A3L08_03850 9cbdd7a490c833acfb0d2cefc51531dd 236 TIGRFAM TIGR00291 RNA_SBDS: rRNA metabolism protein, SBDS family 3 231 4.1E-90 T 23-10-2018 IPR002140 Ribosome maturation protein Sdo1/SBDS GO:0042256 A3L08_03850 9cbdd7a490c833acfb0d2cefc51531dd 236 SUPERFAMILY SSF89895 4 87 1.44E-25 T 23-10-2018 IPR036786 Ribosome maturation protein SBDS, N-terminal domain superfamily A3L08_03850 9cbdd7a490c833acfb0d2cefc51531dd 236 SUPERFAMILY SSF54980 157 227 8.39E-22 T 23-10-2018 IPR035647 EF-G domain III/V-like A3L08_03850 9cbdd7a490c833acfb0d2cefc51531dd 236 SUPERFAMILY SSF109728 88 161 9.94E-25 T 23-10-2018 IPR037188 Ribosome maturation protein Sdo1/SBDS, central domain superfamily A3L08_03850 9cbdd7a490c833acfb0d2cefc51531dd 236 Pfam PF01172 Shwachman-Bodian-Diamond syndrome (SBDS) protein 8 94 8.7E-26 T 23-10-2018 IPR019783 Ribosome maturation protein SBDS, N-terminal A3L08_03850 9cbdd7a490c833acfb0d2cefc51531dd 236 ProSitePatterns PS01267 Uncharacterized protein family UPF0023 signature. 37 56 - T 23-10-2018 IPR018023 Ribosome maturation protein SBDS, conserved site A3L08_03850 9cbdd7a490c833acfb0d2cefc51531dd 236 Pfam PF09377 SBDS protein C-terminal domain 101 210 2.5E-17 T 23-10-2018 IPR018978 Ribosome maturation protein SBDS, C-terminal GO:0042254 A3L08_03850 9cbdd7a490c833acfb0d2cefc51531dd 236 Gene3D G3DSA:3.30.1250.10 8 87 4.8E-31 T 23-10-2018 IPR036786 Ribosome maturation protein SBDS, N-terminal domain superfamily A3L08_03850 9cbdd7a490c833acfb0d2cefc51531dd 236 Gene3D G3DSA:1.10.10.900 88 162 1.6E-29 T 23-10-2018 IPR037188 Ribosome maturation protein Sdo1/SBDS, central domain superfamily A3L08_03255 f60350b3eb868bb6a59208e468cbe72e 438 Gene3D G3DSA:3.90.600.10 329 418 5.7E-8 T 23-10-2018 IPR037123 Phosphoribosylglycinamide synthetase, C-domain superfamily GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A3L08_03255 f60350b3eb868bb6a59208e468cbe72e 438 Gene3D G3DSA:3.30.1490.20 121 187 1.1E-14 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 A3L08_03255 f60350b3eb868bb6a59208e468cbe72e 438 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 1 416 8.6E-147 T 23-10-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A3L08_03255 f60350b3eb868bb6a59208e468cbe72e 438 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 1 418 36.128 T 23-10-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A3L08_03255 f60350b3eb868bb6a59208e468cbe72e 438 SUPERFAMILY SSF52440 1 102 7.48E-23 T 23-10-2018 IPR016185 Pre-ATP-grasp domain superfamily A3L08_03255 f60350b3eb868bb6a59208e468cbe72e 438 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 330 416 8.1E-12 T 23-10-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A3L08_03255 f60350b3eb868bb6a59208e468cbe72e 438 SUPERFAMILY SSF51246 327 416 2.59E-15 T 23-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 A3L08_03255 f60350b3eb868bb6a59208e468cbe72e 438 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 1 101 2.5E-20 T 23-10-2018 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A3L08_03255 f60350b3eb868bb6a59208e468cbe72e 438 Gene3D G3DSA:3.40.50.20 2 94 1.7E-18 T 23-10-2018 A3L08_03255 f60350b3eb868bb6a59208e468cbe72e 438 SMART SM01210 328 418 1.1E-17 T 23-10-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A3L08_03255 f60350b3eb868bb6a59208e468cbe72e 438 SUPERFAMILY SSF56059 103 321 6.72E-49 T 23-10-2018 A3L08_03255 f60350b3eb868bb6a59208e468cbe72e 438 ProSitePatterns PS00184 Phosphoribosylglycinamide synthetase signature. 290 297 - T 23-10-2018 IPR020559 Phosphoribosylglycinamide synthetase, conserved site GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A3L08_03255 f60350b3eb868bb6a59208e468cbe72e 438 SMART SM01209 102 296 4.0E-96 T 23-10-2018 A3L08_03255 f60350b3eb868bb6a59208e468cbe72e 438 Gene3D G3DSA:3.30.470.20 189 328 2.7E-48 T 23-10-2018 A3L08_03255 f60350b3eb868bb6a59208e468cbe72e 438 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 102 296 1.8E-61 T 23-10-2018 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A3L08_08890 5633afe753ff21b93949b3036a9c62c7 631 Pfam PF00326 Prolyl oligopeptidase family 421 631 8.6E-60 T 23-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 A3L08_08890 5633afe753ff21b93949b3036a9c62c7 631 SUPERFAMILY SSF53474 374 631 7.88E-71 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold A3L08_08890 5633afe753ff21b93949b3036a9c62c7 631 Pfam PF07676 WD40-like Beta Propeller Repeat 54 89 4.6E-7 T 23-10-2018 IPR011659 WD40-like Beta Propeller A3L08_08890 5633afe753ff21b93949b3036a9c62c7 631 Gene3D G3DSA:2.120.10.30 23 143 2.9E-15 T 23-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like A3L08_08890 5633afe753ff21b93949b3036a9c62c7 631 Gene3D G3DSA:2.120.10.30 149 294 6.8E-8 T 23-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like A3L08_08890 5633afe753ff21b93949b3036a9c62c7 631 SUPERFAMILY SSF82171 24 365 5.36E-34 T 23-10-2018 A3L08_08890 5633afe753ff21b93949b3036a9c62c7 631 Gene3D G3DSA:3.40.50.1820 377 631 1.4E-73 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold A3L08_09440 1006396754fa4ebd7494be21cd794ea3 465 Pfam PF13380 CoA binding domain 13 142 4.9E-20 T 23-10-2018 IPR003781 CoA-binding GO:0048037 A3L08_09440 1006396754fa4ebd7494be21cd794ea3 465 SUPERFAMILY SSF52210 139 298 1.7E-44 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A3L08_09440 1006396754fa4ebd7494be21cd794ea3 465 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 159 296 1.4E-54 T 23-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain A3L08_09440 1006396754fa4ebd7494be21cd794ea3 465 SUPERFAMILY SSF52210 302 459 6.41E-32 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A3L08_09440 1006396754fa4ebd7494be21cd794ea3 465 TIGRFAM TIGR02717 AcCoA-syn-alpha: acetyl coenzyme A synthetase (ADP forming), alpha domain 7 455 5.5E-185 T 23-10-2018 IPR014089 Acetate-CoA ligase [ADP-forming], alpha domain KEGG: 00010+6.2.1.13|KEGG: 00620+6.2.1.13|KEGG: 00640+6.2.1.13|MetaCyc: PWY-5483|MetaCyc: PWY-5535 A3L08_09440 1006396754fa4ebd7494be21cd794ea3 465 SUPERFAMILY SSF51735 6 137 8.09E-38 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L08_09440 1006396754fa4ebd7494be21cd794ea3 465 Gene3D G3DSA:3.40.50.261 138 299 1.3E-63 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A3L08_09440 1006396754fa4ebd7494be21cd794ea3 465 SMART SM00881 9 108 5.7E-39 T 23-10-2018 IPR003781 CoA-binding GO:0048037 A3L08_09440 1006396754fa4ebd7494be21cd794ea3 465 Gene3D G3DSA:3.40.50.720 4 137 5.2E-45 T 23-10-2018 A3L08_09440 1006396754fa4ebd7494be21cd794ea3 465 Gene3D G3DSA:3.40.50.261 300 465 1.7E-49 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A3L08_02485 12cd96e194edc347cd0b306239c3123a 305 Gene3D G3DSA:3.40.50.300 1 241 2.9E-59 T 23-10-2018 A3L08_02485 12cd96e194edc347cd0b306239c3123a 305 SUPERFAMILY SSF52540 2 229 2.83E-56 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_02485 12cd96e194edc347cd0b306239c3123a 305 SMART SM00382 26 229 2.0E-11 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L08_02485 12cd96e194edc347cd0b306239c3123a 305 Pfam PF00005 ABC transporter 17 167 3.9E-30 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L08_02485 12cd96e194edc347cd0b306239c3123a 305 Pfam PF13732 Domain of unknown function (DUF4162) 222 304 2.0E-7 T 23-10-2018 IPR025302 Domain of unknown function DUF4162 A3L08_02485 12cd96e194edc347cd0b306239c3123a 305 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L08_09495 717316d376c3e80ffa02193f60a6e076 228 TIGRFAM TIGR00323 eIF-6: putative translation initiation factor eIF-6 5 226 5.5E-66 T 23-10-2018 IPR002769 Translation initiation factor IF6 GO:0042256|GO:0043022 A3L08_09495 717316d376c3e80ffa02193f60a6e076 228 PIRSF PIRSF006413 2 228 1.8E-80 T 23-10-2018 IPR002769 Translation initiation factor IF6 GO:0042256|GO:0043022 A3L08_09495 717316d376c3e80ffa02193f60a6e076 228 SMART SM00654 4 206 4.3E-108 T 23-10-2018 IPR002769 Translation initiation factor IF6 GO:0042256|GO:0043022 A3L08_09495 717316d376c3e80ffa02193f60a6e076 228 SUPERFAMILY SSF55909 3 226 2.45E-75 T 23-10-2018 A3L08_09495 717316d376c3e80ffa02193f60a6e076 228 Pfam PF01912 eIF-6 family 5 206 3.4E-70 T 23-10-2018 IPR002769 Translation initiation factor IF6 GO:0042256|GO:0043022 A3L08_09495 717316d376c3e80ffa02193f60a6e076 228 Hamap MF_00032 Translation initiation factor 6 [eif6]. 1 228 98.5 T 23-10-2018 IPR002769 Translation initiation factor IF6 GO:0042256|GO:0043022 A3L08_09495 717316d376c3e80ffa02193f60a6e076 228 Gene3D G3DSA:3.75.10.10 1 227 1.9E-80 T 23-10-2018 A3L08_04655 0bde304e4f127fd2626400b0cf6440bb 176 Pfam PF04434 SWIM zinc finger 44 68 7.8E-7 T 23-10-2018 IPR007527 Zinc finger, SWIM-type GO:0008270 A3L08_08955 530262d6f31c37712d367bc7e744c720 872 Pfam PF00270 DEAD/DEAH box helicase 219 382 1.0E-24 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A3L08_08955 530262d6f31c37712d367bc7e744c720 872 SMART SM00487 213 410 5.3E-30 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A3L08_08955 530262d6f31c37712d367bc7e744c720 872 SMART SM00490 453 538 1.8E-19 T 23-10-2018 IPR001650 Helicase, C-terminal A3L08_08955 530262d6f31c37712d367bc7e744c720 872 Gene3D G3DSA:3.40.50.300 404 594 7.3E-30 T 23-10-2018 A3L08_08955 530262d6f31c37712d367bc7e744c720 872 SUPERFAMILY SSF52540 227 552 4.19E-50 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_08955 530262d6f31c37712d367bc7e744c720 872 Gene3D G3DSA:3.40.50.300 200 402 2.2E-51 T 23-10-2018 A3L08_08955 530262d6f31c37712d367bc7e744c720 872 Pfam PF00271 Helicase conserved C-terminal domain 418 536 1.8E-13 T 23-10-2018 IPR001650 Helicase, C-terminal A3L08_04385 00052df23b3577c251c0107112a4ace9 334 TIGRFAM TIGR00549 mevalon_kin: mevalonate kinase 7 298 1.1E-83 T 23-10-2018 IPR006205 Mevalonate kinase GO:0004496|GO:0005524|GO:0005737|GO:0008299 KEGG: 00900+2.7.1.36|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-2426168 A3L08_04385 00052df23b3577c251c0107112a4ace9 334 Pfam PF00288 GHMP kinases N terminal domain 103 169 3.9E-16 T 23-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 A3L08_04385 00052df23b3577c251c0107112a4ace9 334 PRINTS PR00959 Mevalonate kinase family signature 7 31 6.7E-29 T 23-10-2018 A3L08_04385 00052df23b3577c251c0107112a4ace9 334 PRINTS PR00959 Mevalonate kinase family signature 150 169 6.7E-29 T 23-10-2018 A3L08_04385 00052df23b3577c251c0107112a4ace9 334 PRINTS PR00959 Mevalonate kinase family signature 107 129 6.7E-29 T 23-10-2018 A3L08_04385 00052df23b3577c251c0107112a4ace9 334 PRINTS PR00959 Mevalonate kinase family signature 283 300 6.7E-29 T 23-10-2018 A3L08_04385 00052df23b3577c251c0107112a4ace9 334 Pfam PF08544 GHMP kinases C terminal 243 310 5.9E-14 T 23-10-2018 IPR013750 GHMP kinase, C-terminal domain A3L08_04385 00052df23b3577c251c0107112a4ace9 334 Gene3D G3DSA:3.30.230.10 1 183 8.5E-51 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A3L08_04385 00052df23b3577c251c0107112a4ace9 334 Hamap MF_00217 Mevalonate kinase [mvk]. 3 327 59.225 T 23-10-2018 IPR022937 Mevalonate kinase, archaeal GO:0004496 KEGG: 00900+2.7.1.36|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-922 A3L08_04385 00052df23b3577c251c0107112a4ace9 334 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 109 120 - T 23-10-2018 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 A3L08_04385 00052df23b3577c251c0107112a4ace9 334 SUPERFAMILY SSF54211 3 180 6.53E-45 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A3L08_04385 00052df23b3577c251c0107112a4ace9 334 Gene3D G3DSA:3.30.70.890 187 319 2.3E-41 T 23-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily A3L08_04385 00052df23b3577c251c0107112a4ace9 334 SUPERFAMILY SSF55060 183 329 6.3E-38 T 23-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily A3L08_04180 31ea01c12be89a5acef3c91a736e36b4 90 Hamap MF_00349 50S ribosomal protein L34e [rpl34e]. 1 86 28.88 T 23-10-2018 IPR008195 Ribosomal protein L34Ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_04180 31ea01c12be89a5acef3c91a736e36b4 90 PRINTS PR01250 Ribosomal protein L34 signature 18 35 1.9E-16 T 23-10-2018 IPR008195 Ribosomal protein L34Ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_04180 31ea01c12be89a5acef3c91a736e36b4 90 PRINTS PR01250 Ribosomal protein L34 signature 5 18 1.9E-16 T 23-10-2018 IPR008195 Ribosomal protein L34Ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_04180 31ea01c12be89a5acef3c91a736e36b4 90 PRINTS PR01250 Ribosomal protein L34 signature 56 78 1.9E-16 T 23-10-2018 IPR008195 Ribosomal protein L34Ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_04180 31ea01c12be89a5acef3c91a736e36b4 90 PRINTS PR01250 Ribosomal protein L34 signature 36 46 1.9E-16 T 23-10-2018 IPR008195 Ribosomal protein L34Ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_04180 31ea01c12be89a5acef3c91a736e36b4 90 ProSitePatterns PS01145 Ribosomal protein L34e signature. 7 20 - T 23-10-2018 IPR018065 Ribosomal protein L34e, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_04180 31ea01c12be89a5acef3c91a736e36b4 90 Gene3D G3DSA:3.40.1800.40 29 86 2.0E-9 T 23-10-2018 IPR038562 Ribosomal protein L34Ae superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_04180 31ea01c12be89a5acef3c91a736e36b4 90 Pfam PF01199 Ribosomal protein L34e 3 83 5.0E-24 T 23-10-2018 IPR008195 Ribosomal protein L34Ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_05785 b4eeda5602d9382aaa1e5a01111e4718 322 Gene3D G3DSA:3.90.650.10 139 309 2.5E-43 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A3L08_05785 b4eeda5602d9382aaa1e5a01111e4718 322 TIGRFAM TIGR01379 thiL: thiamine-phosphate kinase 3 309 2.3E-84 T 23-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 A3L08_05785 b4eeda5602d9382aaa1e5a01111e4718 322 Hamap MF_02128 Thiamine-monophosphate kinase [thiL]. 1 309 28.424 T 23-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 A3L08_05785 b4eeda5602d9382aaa1e5a01111e4718 322 Gene3D G3DSA:3.30.1330.10 1 138 7.1E-35 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A3L08_05785 b4eeda5602d9382aaa1e5a01111e4718 322 Pfam PF00586 AIR synthase related protein, N-terminal domain 24 133 7.4E-18 T 23-10-2018 IPR016188 PurM-like, N-terminal domain A3L08_05785 b4eeda5602d9382aaa1e5a01111e4718 322 SUPERFAMILY SSF56042 137 295 1.33E-37 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A3L08_05785 b4eeda5602d9382aaa1e5a01111e4718 322 SUPERFAMILY SSF55326 10 133 4.78E-31 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A3L08_05785 b4eeda5602d9382aaa1e5a01111e4718 322 PIRSF PIRSF005303 1 309 1.8E-92 T 23-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 A3L08_05785 b4eeda5602d9382aaa1e5a01111e4718 322 Pfam PF02769 AIR synthase related protein, C-terminal domain 145 292 9.5E-10 T 23-10-2018 IPR010918 PurM-like, C-terminal domain A3L08_05735 fa56a91a8c22cbaaf55b7f6a7057aa91 280 SUPERFAMILY SSF53335 12 266 7.19E-62 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L08_05735 fa56a91a8c22cbaaf55b7f6a7057aa91 280 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 46 73 - T 23-10-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 A3L08_05735 fa56a91a8c22cbaaf55b7f6a7057aa91 280 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 14 267 45.662 T 23-10-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 A3L08_05735 fa56a91a8c22cbaaf55b7f6a7057aa91 280 Pfam PF00398 Ribosomal RNA adenine dimethylase 15 234 5.0E-49 T 23-10-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm A3L08_05735 fa56a91a8c22cbaaf55b7f6a7057aa91 280 SMART SM00650 30 193 3.0E-76 T 23-10-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 A3L08_05735 fa56a91a8c22cbaaf55b7f6a7057aa91 280 Gene3D G3DSA:1.10.8.100 195 270 5.9E-10 T 23-10-2018 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201|Reactome: R-HSA-6793080 A3L08_05735 fa56a91a8c22cbaaf55b7f6a7057aa91 280 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 15 264 5.2E-73 T 23-10-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 A3L08_05735 fa56a91a8c22cbaaf55b7f6a7057aa91 280 Gene3D G3DSA:3.40.50.150 2 193 5.4E-63 T 23-10-2018 A3L08_07270 88c00ee74e8323b65e0b83011efebc3b 223 Gene3D G3DSA:3.40.50.300 1 218 1.8E-74 T 23-10-2018 A3L08_07270 88c00ee74e8323b65e0b83011efebc3b 223 ProSitePatterns PS00113 Adenylate kinase signature. 79 90 - T 23-10-2018 IPR033690 Adenylate kinase, conserved site KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A3L08_07270 88c00ee74e8323b65e0b83011efebc3b 223 PRINTS PR00094 Adenylate kinase signature 79 95 2.9E-29 T 23-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A3L08_07270 88c00ee74e8323b65e0b83011efebc3b 223 PRINTS PR00094 Adenylate kinase signature 175 189 2.9E-29 T 23-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A3L08_07270 88c00ee74e8323b65e0b83011efebc3b 223 PRINTS PR00094 Adenylate kinase signature 4 17 2.9E-29 T 23-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A3L08_07270 88c00ee74e8323b65e0b83011efebc3b 223 PRINTS PR00094 Adenylate kinase signature 158 173 2.9E-29 T 23-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A3L08_07270 88c00ee74e8323b65e0b83011efebc3b 223 PRINTS PR00094 Adenylate kinase signature 32 46 2.9E-29 T 23-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A3L08_07270 88c00ee74e8323b65e0b83011efebc3b 223 Pfam PF05191 Adenylate kinase, active site lid 125 160 5.7E-15 T 23-10-2018 IPR007862 Adenylate kinase, active site lid domain GO:0004017 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 A3L08_07270 88c00ee74e8323b65e0b83011efebc3b 223 TIGRFAM TIGR01351 adk: adenylate kinase 2 209 1.2E-71 T 23-10-2018 IPR006259 Adenylate kinase subfamily GO:0004017|GO:0005524|GO:0016776 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 A3L08_07270 88c00ee74e8323b65e0b83011efebc3b 223 Hamap MF_00235 Adenylate kinase [adk]. 1 211 44.613 T 23-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A3L08_07270 88c00ee74e8323b65e0b83011efebc3b 223 SUPERFAMILY SSF52540 2 212 1.38E-38 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_07270 88c00ee74e8323b65e0b83011efebc3b 223 Pfam PF00406 Adenylate kinase 5 188 1.7E-42 T 23-10-2018 A3L08_04230 14492dc482730950d47d2a3377b0bc90 260 ProSitePatterns PS00446 RNA polymerases D / 30 to 40 Kd subunits signature. 28 68 - T 23-10-2018 IPR001514 DNA-directed RNA polymerase, 30-40kDa subunit, conserved site GO:0003677|GO:0003899|GO:0006351 A3L08_04230 14492dc482730950d47d2a3377b0bc90 260 SUPERFAMILY SSF56553 39 149 1.29E-29 T 23-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L08_04230 14492dc482730950d47d2a3377b0bc90 260 SMART SM00662 14 254 2.1E-85 T 23-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L08_04230 14492dc482730950d47d2a3377b0bc90 260 Hamap MF_00320 DNA-directed RNA polymerase subunit D [rpoD]. 3 257 32.868 T 23-10-2018 IPR022842 DNA-directed RNA polymerase subunit D (Rpo3) GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L08_04230 14492dc482730950d47d2a3377b0bc90 260 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 46 148 1.3E-28 T 23-10-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L08_04230 14492dc482730950d47d2a3377b0bc90 260 Gene3D G3DSA:2.170.120.12 40 147 6.9E-96 T 23-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L08_04230 14492dc482730950d47d2a3377b0bc90 260 Gene3D G3DSA:3.30.1360.10 6 251 6.9E-96 T 23-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L08_04230 14492dc482730950d47d2a3377b0bc90 260 Gene3D G3DSA:3.30.70.3110 157 218 6.9E-96 T 23-10-2018 A3L08_04230 14492dc482730950d47d2a3377b0bc90 260 SUPERFAMILY SSF55257 2 257 2.75E-29 T 23-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L08_04230 14492dc482730950d47d2a3377b0bc90 260 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 16 247 1.4E-19 T 23-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L08_06435 84cd800649818bc5085f42d054c0999e 267 Pfam PF10869 Protein of unknown function (DUF2666) 4 116 8.5E-12 T 23-10-2018 IPR022620 Protein of unknown function DUF2666 A3L08_06435 84cd800649818bc5085f42d054c0999e 267 Pfam PF10869 Protein of unknown function (DUF2666) 138 266 2.8E-37 T 23-10-2018 IPR022620 Protein of unknown function DUF2666 A3L08_06435 84cd800649818bc5085f42d054c0999e 267 ProDom PD033097 PH0063 MJ0596 ARCHAEAL PF2050 138 266 1.0E-42 T 23-10-2018 IPR022620 Protein of unknown function DUF2666 A3L08_06435 84cd800649818bc5085f42d054c0999e 267 ProDom PD033097 PH0063 MJ0596 ARCHAEAL PF2050 4 88 3.0E-23 T 23-10-2018 IPR022620 Protein of unknown function DUF2666 A3L08_00740 8722c7793ad8378666a0b104b9970560 390 SUPERFAMILY SSF54675 2 115 2.36E-33 T 23-10-2018 A3L08_00740 8722c7793ad8378666a0b104b9970560 390 Gene3D G3DSA:3.20.140.10 303 389 5.4E-6 T 23-10-2018 A3L08_00740 8722c7793ad8378666a0b104b9970560 390 PIRSF PIRSF000484 9 72 3.7 T 23-10-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 A3L08_00740 8722c7793ad8378666a0b104b9970560 390 PIRSF PIRSF000484 68 388 2.0E-49 T 23-10-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 A3L08_00740 8722c7793ad8378666a0b104b9970560 390 Gene3D G3DSA:3.20.20.70 107 297 1.0E-64 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L08_00740 8722c7793ad8378666a0b104b9970560 390 Gene3D G3DSA:3.90.1170.20 1 106 2.9E-46 T 23-10-2018 IPR037128 Quinolinate phosphoribosyl transferase, N-terminal domain superfamily GO:0016763 Reactome: R-HSA-196807 A3L08_00740 8722c7793ad8378666a0b104b9970560 390 SUPERFAMILY SSF51690 112 386 6.93E-79 T 23-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 A3L08_00740 8722c7793ad8378666a0b104b9970560 390 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 53 113 5.3E-6 T 23-10-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 A3L08_00740 8722c7793ad8378666a0b104b9970560 390 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 115 303 3.2E-26 T 23-10-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 Reactome: R-HSA-196807 A3L08_09330 298c13a82492dbdead05ebe658aaa0c7 190 Gene3D G3DSA:3.30.70.1450 111 189 9.8E-19 T 23-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 A3L08_09330 298c13a82492dbdead05ebe658aaa0c7 190 SUPERFAMILY SSF116726 103 182 2.62E-17 T 23-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 A3L08_09330 298c13a82492dbdead05ebe658aaa0c7 190 Pfam PF01895 PhoU domain 11 95 1.6E-9 T 23-10-2018 IPR026022 PhoU domain A3L08_09330 298c13a82492dbdead05ebe658aaa0c7 190 Pfam PF02080 TrkA-C domain 118 183 5.5E-16 T 23-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A3L08_09330 298c13a82492dbdead05ebe658aaa0c7 190 SUPERFAMILY SSF109755 3 97 5.23E-17 T 23-10-2018 A3L08_09330 298c13a82492dbdead05ebe658aaa0c7 190 Gene3D G3DSA:1.20.58.220 1 110 4.9E-20 T 23-10-2018 IPR038078 PhoU-like domain superfamily A3L08_08440 0a179c673c7ee1e317ee31b2e7174dbb 330 Gene3D G3DSA:3.40.50.300 2 330 1.4E-86 T 23-10-2018 A3L08_08440 0a179c673c7ee1e317ee31b2e7174dbb 330 Pfam PF02374 Anion-transporting ATPase 12 327 4.5E-72 T 23-10-2018 IPR025723 Anion-transporting ATPase-like domain Reactome: R-HSA-381038 A3L08_08440 0a179c673c7ee1e317ee31b2e7174dbb 330 TIGRFAM TIGR00345 GET3_arsA_TRC40: transport-energizing ATPase, TRC40/GET3/ArsA family 15 323 2.3E-73 T 23-10-2018 IPR016300 Arsenical pump ATPase, ArsA/GET3 GO:0005524|GO:0016887 Reactome: R-HSA-381038 A3L08_08440 0a179c673c7ee1e317ee31b2e7174dbb 330 SUPERFAMILY SSF52540 11 321 4.15E-44 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_03815 48bdc4eeb407eaffed3a8f58ec2196d1 637 SUPERFAMILY SSF54862 565 629 1.36E-13 T 23-10-2018 A3L08_03815 48bdc4eeb407eaffed3a8f58ec2196d1 637 Gene3D G3DSA:3.30.70.20 575 636 5.0E-10 T 23-10-2018 A3L08_03815 48bdc4eeb407eaffed3a8f58ec2196d1 637 Pfam PF00037 4Fe-4S binding domain 606 628 1.5E-5 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L08_03815 48bdc4eeb407eaffed3a8f58ec2196d1 637 Gene3D G3DSA:3.40.50.970 5 198 3.9E-55 T 23-10-2018 A3L08_03815 48bdc4eeb407eaffed3a8f58ec2196d1 637 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 414 555 4.5E-32 T 23-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 A3L08_03815 48bdc4eeb407eaffed3a8f58ec2196d1 637 TIGRFAM TIGR03336 IOR_alpha: indolepyruvate ferredoxin oxidoreductase, alpha subunit 21 627 2.1E-221 T 23-10-2018 IPR017721 Indolepyruvate ferredoxin oxidoreductase, alpha subunit GO:0043805|GO:0055114 A3L08_03815 48bdc4eeb407eaffed3a8f58ec2196d1 637 Gene3D G3DSA:3.40.50.970 413 570 8.9E-24 T 23-10-2018 A3L08_03815 48bdc4eeb407eaffed3a8f58ec2196d1 637 SUPERFAMILY SSF52922 247 333 1.66E-7 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A3L08_03815 48bdc4eeb407eaffed3a8f58ec2196d1 637 PIRSF PIRSF006439 11 634 1.0E-224 T 23-10-2018 IPR017721 Indolepyruvate ferredoxin oxidoreductase, alpha subunit GO:0043805|GO:0055114 A3L08_03815 48bdc4eeb407eaffed3a8f58ec2196d1 637 SUPERFAMILY SSF52518 20 245 8.96E-58 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold A3L08_03815 48bdc4eeb407eaffed3a8f58ec2196d1 637 SUPERFAMILY SSF52518 377 562 1.62E-37 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold A3L08_03815 48bdc4eeb407eaffed3a8f58ec2196d1 637 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 33 215 1.7E-14 T 23-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 A3L08_03815 48bdc4eeb407eaffed3a8f58ec2196d1 637 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 612 623 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L08_00890 3374a916044f1a42f291a2da99f58a03 526 TIGRFAM TIGR00467 lysS_arch: lysine--tRNA ligase 2 522 4.2E-161 T 23-10-2018 IPR002904 Lysine-tRNA ligase GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 A3L08_00890 3374a916044f1a42f291a2da99f58a03 526 SUPERFAMILY SSF48163 323 523 2.88E-50 T 23-10-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 A3L08_00890 3374a916044f1a42f291a2da99f58a03 526 Hamap MF_00177 Lysine--tRNA ligase [lysS]. 2 526 38.137 T 23-10-2018 IPR002904 Lysine-tRNA ligase GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 A3L08_00890 3374a916044f1a42f291a2da99f58a03 526 Gene3D G3DSA:2.30.30.300 170 213 5.2E-110 T 23-10-2018 IPR023386 Lysine-tRNA ligase, insertion domain superfamily GO:0004824 KEGG: 00970+6.1.1.6 A3L08_00890 3374a916044f1a42f291a2da99f58a03 526 Gene3D G3DSA:3.40.50.620 4 270 5.2E-110 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L08_00890 3374a916044f1a42f291a2da99f58a03 526 Gene3D G3DSA:1.10.10.770 319 433 6.2E-41 T 23-10-2018 A3L08_00890 3374a916044f1a42f291a2da99f58a03 526 Gene3D G3DSA:1.10.10.860 271 318 2.3E-23 T 23-10-2018 A3L08_00890 3374a916044f1a42f291a2da99f58a03 526 Gene3D G3DSA:1.10.10.350 434 526 5.4E-25 T 23-10-2018 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 A3L08_00890 3374a916044f1a42f291a2da99f58a03 526 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 30 39 - T 23-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L08_00890 3374a916044f1a42f291a2da99f58a03 526 Pfam PF01921 tRNA synthetases class I (K) 3 362 1.3E-138 T 23-10-2018 IPR002904 Lysine-tRNA ligase GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 A3L08_00890 3374a916044f1a42f291a2da99f58a03 526 SUPERFAMILY SSF52374 3 319 5.36E-67 T 23-10-2018 A3L08_06310 86ced74e87b791192a72e7e79ad981c1 476 SUPERFAMILY SSF102114 173 410 1.44E-51 T 23-10-2018 A3L08_06310 86ced74e87b791192a72e7e79ad981c1 476 Gene3D G3DSA:3.80.30.20 205 403 5.0E-33 T 23-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe A3L08_06310 86ced74e87b791192a72e7e79ad981c1 476 Pfam PF04055 Radical SAM superfamily 212 374 1.4E-25 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L08_06310 86ced74e87b791192a72e7e79ad981c1 476 Pfam PF02310 B12 binding domain 28 140 3.6E-8 T 23-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 A3L08_06310 86ced74e87b791192a72e7e79ad981c1 476 SMART SM00729 206 418 2.0E-42 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A3L08_08950 0f08d3a01597b9d30349501785bfd39a 268 Pfam PF01889 Membrane protein of unknown function DUF63 9 266 2.1E-74 T 23-10-2018 IPR002749 Protein of unknown function DUF63 A3L08_00670 4ebeb14037aa82a58358277e9357d5f1 388 Gene3D G3DSA:3.30.9.10 82 317 2.6E-117 T 23-10-2018 A3L08_00670 4ebeb14037aa82a58358277e9357d5f1 388 SUPERFAMILY SSF54373 225 318 1.9E-7 T 23-10-2018 A3L08_00670 4ebeb14037aa82a58358277e9357d5f1 388 Pfam PF01266 FAD dependent oxidoreductase 3 355 1.6E-74 T 23-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 A3L08_00670 4ebeb14037aa82a58358277e9357d5f1 388 SUPERFAMILY SSF51905 2 379 6.47E-61 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L08_00670 4ebeb14037aa82a58358277e9357d5f1 388 Gene3D G3DSA:3.50.50.60 4 359 2.6E-117 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L08_04060 17617297b87e2fc3fc3cd89c134ab28e 239 SUPERFAMILY SSF50249 2 93 2.4E-23 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L08_04060 17617297b87e2fc3fc3cd89c134ab28e 239 Gene3D G3DSA:4.10.950.10 163 239 3.4E-34 T 23-10-2018 IPR014726 Ribosomal protein L2, domain 3 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_04060 17617297b87e2fc3fc3cd89c134ab28e 239 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 11 84 1.8E-20 T 23-10-2018 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L08_04060 17617297b87e2fc3fc3cd89c134ab28e 239 Gene3D G3DSA:2.30.30.30 85 162 1.7E-29 T 23-10-2018 IPR014722 Ribosomal protein L2, domain 2 A3L08_04060 17617297b87e2fc3fc3cd89c134ab28e 239 SMART SM01382 91 223 2.0E-60 T 23-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 A3L08_04060 17617297b87e2fc3fc3cd89c134ab28e 239 SMART SM01383 11 85 4.9E-25 T 23-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L08_04060 17617297b87e2fc3fc3cd89c134ab28e 239 Hamap MF_01320_A 50S ribosomal protein L2 [rplB]. 1 238 42.239 T 23-10-2018 IPR023672 Ribosomal protein L2, archaeal-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_04060 17617297b87e2fc3fc3cd89c134ab28e 239 Gene3D G3DSA:2.40.50.140 1 81 3.7E-31 T 23-10-2018 A3L08_04060 17617297b87e2fc3fc3cd89c134ab28e 239 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 92 222 4.4E-42 T 23-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 A3L08_04060 17617297b87e2fc3fc3cd89c134ab28e 239 SUPERFAMILY SSF50104 94 237 1.87E-47 T 23-10-2018 IPR008991 Translation protein SH3-like domain superfamily A3L08_04060 17617297b87e2fc3fc3cd89c134ab28e 239 PIRSF PIRSF002158 1 239 1.1E-72 T 23-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L08_04170 7c2a2a3753a727e478f1a2ff49396247 196 Gene3D G3DSA:3.40.50.300 3 189 1.4E-57 T 23-10-2018 A3L08_04170 7c2a2a3753a727e478f1a2ff49396247 196 Pfam PF13207 AAA domain 8 145 1.9E-36 T 23-10-2018 A3L08_04170 7c2a2a3753a727e478f1a2ff49396247 196 SUPERFAMILY SSF52540 1 188 2.21E-20 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_04170 7c2a2a3753a727e478f1a2ff49396247 196 Hamap MF_00234 Adenylate kinase [adkA]. 3 189 44.493 T 23-10-2018 IPR023477 Adenylate kinase AdkA GO:0004017 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 A3L08_07125 fc60ae63170e6ff3587af4f95be89832 719 SUPERFAMILY SSF52317 471 717 1.21E-25 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A3L08_07125 fc60ae63170e6ff3587af4f95be89832 719 Gene3D G3DSA:3.40.50.880 487 714 4.6E-12 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A3L08_07125 fc60ae63170e6ff3587af4f95be89832 719 Pfam PF06283 Trehalose utilisation 507 630 7.5E-9 T 23-10-2018 IPR029010 ThuA-like domain A3L08_07125 fc60ae63170e6ff3587af4f95be89832 719 Pfam PF09822 ABC-type uncharacterized transport system 375 594 1.4E-10 T 23-10-2018 IPR019196 ABC-type uncharacterised transport system Reactome: R-HSA-5610787|Reactome: R-HSA-5620924 A3L08_01730 735bf8cef1a39399b2c15b210a15ea5a 70 Pfam PF01938 TRAM domain 14 70 5.5E-15 T 23-10-2018 IPR002792 TRAM domain A3L08_01730 735bf8cef1a39399b2c15b210a15ea5a 70 Gene3D G3DSA:2.40.50.140 5 70 4.1E-26 T 23-10-2018 A3L08_01730 735bf8cef1a39399b2c15b210a15ea5a 70 SUPERFAMILY SSF50249 10 70 1.14E-16 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L08_06935 92777d1fb09a85c901cd305672a7dffd 487 Pfam PF00232 Glycosyl hydrolase family 1 3 92 3.8E-8 T 23-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A3L08_06935 92777d1fb09a85c901cd305672a7dffd 487 Pfam PF00232 Glycosyl hydrolase family 1 127 470 1.1E-57 T 23-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A3L08_06935 92777d1fb09a85c901cd305672a7dffd 487 Gene3D G3DSA:3.20.20.80 1 486 6.9E-156 T 23-10-2018 A3L08_06935 92777d1fb09a85c901cd305672a7dffd 487 PRINTS PR00131 Glycosyl hydrolase family 1 signature 416 433 1.2E-19 T 23-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A3L08_06935 92777d1fb09a85c901cd305672a7dffd 487 PRINTS PR00131 Glycosyl hydrolase family 1 signature 440 452 1.2E-19 T 23-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A3L08_06935 92777d1fb09a85c901cd305672a7dffd 487 PRINTS PR00131 Glycosyl hydrolase family 1 signature 383 391 1.2E-19 T 23-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A3L08_06935 92777d1fb09a85c901cd305672a7dffd 487 PRINTS PR00131 Glycosyl hydrolase family 1 signature 313 327 1.2E-19 T 23-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A3L08_06935 92777d1fb09a85c901cd305672a7dffd 487 PRINTS PR00131 Glycosyl hydrolase family 1 signature 395 406 1.2E-19 T 23-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A3L08_06935 92777d1fb09a85c901cd305672a7dffd 487 SUPERFAMILY SSF51445 2 476 9.81E-134 T 23-10-2018 IPR017853 Glycoside hydrolase superfamily A3L08_06935 92777d1fb09a85c901cd305672a7dffd 487 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 8 22 - T 23-10-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site A3L08_09450 7fa9951da1ab161965749a87bf21e398 341 Hamap MF_00614 Flap endonuclease 1 [fen]. 1 340 147.92 T 23-10-2018 IPR023426 Flap endonuclease 1 GO:0016788 Reactome: R-HSA-110362|Reactome: R-HSA-162594|Reactome: R-HSA-174437|Reactome: R-HSA-5651801|Reactome: R-HSA-5685939|Reactome: R-HSA-69166 A3L08_09450 7fa9951da1ab161965749a87bf21e398 341 ProSitePatterns PS00841 XPG protein signature 1. 73 87 - T 23-10-2018 IPR019974 XPG conserved site GO:0016788 A3L08_09450 7fa9951da1ab161965749a87bf21e398 341 SMART SM00484 140 221 1.3E-38 T 23-10-2018 IPR006086 XPG-I domain GO:0004518 A3L08_09450 7fa9951da1ab161965749a87bf21e398 341 SUPERFAMILY SSF88723 8 236 9.48E-68 T 23-10-2018 IPR029060 PIN-like domain superfamily A3L08_09450 7fa9951da1ab161965749a87bf21e398 341 Gene3D G3DSA:1.10.150.20 221 281 1.2E-21 T 23-10-2018 A3L08_09450 7fa9951da1ab161965749a87bf21e398 341 SMART SM00485 1 101 4.2E-51 T 23-10-2018 IPR006085 XPG N-terminal GO:0004518|GO:0006281 A3L08_09450 7fa9951da1ab161965749a87bf21e398 341 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 139 156 5.4E-33 T 23-10-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 A3L08_09450 7fa9951da1ab161965749a87bf21e398 341 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 226 241 5.4E-33 T 23-10-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 A3L08_09450 7fa9951da1ab161965749a87bf21e398 341 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 75 94 5.4E-33 T 23-10-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 A3L08_09450 7fa9951da1ab161965749a87bf21e398 341 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 21 35 5.4E-33 T 23-10-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 A3L08_09450 7fa9951da1ab161965749a87bf21e398 341 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 160 180 5.4E-33 T 23-10-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 A3L08_09450 7fa9951da1ab161965749a87bf21e398 341 Pfam PF00867 XPG I-region 141 236 1.0E-28 T 23-10-2018 IPR006086 XPG-I domain GO:0004518 A3L08_09450 7fa9951da1ab161965749a87bf21e398 341 SMART SM00279 223 257 2.1E-11 T 23-10-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 A3L08_09450 7fa9951da1ab161965749a87bf21e398 341 TIGRFAM TIGR03674 fen_arch: flap structure-specific endonuclease 1 338 1.8E-158 T 23-10-2018 IPR019973 Flap structure-specific endonuclease, archaea GO:0016788 A3L08_09450 7fa9951da1ab161965749a87bf21e398 341 Gene3D G3DSA:3.40.50.1010 1 220 1.4E-90 T 23-10-2018 A3L08_09450 7fa9951da1ab161965749a87bf21e398 341 SUPERFAMILY SSF47807 221 339 1.12E-32 T 23-10-2018 IPR036279 5'-3' exonuclease, C-terminal domain superfamily A3L08_09450 7fa9951da1ab161965749a87bf21e398 341 Pfam PF00752 XPG N-terminal domain 12 101 2.2E-22 T 23-10-2018 IPR006085 XPG N-terminal GO:0004518|GO:0006281 A3L08_00875 31a891e3c4479bbec00ea6eb914a7568 388 SUPERFAMILY SSF103473 11 386 1.31E-39 T 23-10-2018 IPR036259 MFS transporter superfamily A3L08_00875 31a891e3c4479bbec00ea6eb914a7568 388 Gene3D G3DSA:1.20.1250.20 11 198 2.1E-14 T 23-10-2018 A3L08_00875 31a891e3c4479bbec00ea6eb914a7568 388 Gene3D G3DSA:1.20.1250.20 209 388 1.6E-14 T 23-10-2018 A3L08_00875 31a891e3c4479bbec00ea6eb914a7568 388 Pfam PF07690 Major Facilitator Superfamily 24 345 3.3E-17 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A3L08_03055 181188d535d3fa3fa963086ef7a608cb 156 Gene3D G3DSA:3.40.50.1010 5 147 2.5E-9 T 23-10-2018 A3L08_03055 181188d535d3fa3fa963086ef7a608cb 156 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 6 142 9.621 T 23-10-2018 IPR022907 VapC family GO:0004540 A3L08_03055 181188d535d3fa3fa963086ef7a608cb 156 SUPERFAMILY SSF88723 5 134 4.77E-17 T 23-10-2018 IPR029060 PIN-like domain superfamily A3L08_03055 181188d535d3fa3fa963086ef7a608cb 156 Pfam PF01850 PIN domain 7 134 3.2E-20 T 23-10-2018 IPR002716 PIN domain A3L08_03055 181188d535d3fa3fa963086ef7a608cb 156 SMART SM00670 4 133 1.7E-9 T 23-10-2018 IPR002716 PIN domain A3L08_03160 ea96124432940aa26adb09c86f9925f1 341 Gene3D G3DSA:1.25.40.10 38 127 1.6E-11 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A3L08_03160 ea96124432940aa26adb09c86f9925f1 341 SUPERFAMILY SSF48452 52 238 1.2E-24 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A3L08_03160 ea96124432940aa26adb09c86f9925f1 341 SMART SM00028 211 244 91.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A3L08_03160 ea96124432940aa26adb09c86f9925f1 341 SMART SM00028 134 167 2.5 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A3L08_03160 ea96124432940aa26adb09c86f9925f1 341 SMART SM00028 174 207 20.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A3L08_03160 ea96124432940aa26adb09c86f9925f1 341 SMART SM00028 93 126 0.0025 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A3L08_03160 ea96124432940aa26adb09c86f9925f1 341 SMART SM00028 55 88 31.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A3L08_03160 ea96124432940aa26adb09c86f9925f1 341 Gene3D G3DSA:1.25.40.10 128 324 7.8E-17 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A3L08_03160 ea96124432940aa26adb09c86f9925f1 341 Pfam PF13424 Tetratricopeptide repeat 58 121 1.3E-8 T 23-10-2018 A3L08_03160 ea96124432940aa26adb09c86f9925f1 341 Pfam PF13424 Tetratricopeptide repeat 133 203 9.8E-11 T 23-10-2018 A3L08_00175 a10d0e334e8011f829722285a0e474ab 417 ProSitePatterns PS01134 FtsZ protein signature 1. 68 102 - T 23-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 A3L08_00175 a10d0e334e8011f829722285a0e474ab 417 Pfam PF12327 FtsZ family, C-terminal domain 253 347 5.5E-24 T 23-10-2018 IPR024757 Cell division protein FtsZ, C-terminal A3L08_00175 a10d0e334e8011f829722285a0e474ab 417 SUPERFAMILY SSF52490 36 239 3.53E-57 T 23-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 A3L08_00175 a10d0e334e8011f829722285a0e474ab 417 SMART SM00865 238 355 1.1E-37 T 23-10-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-380320 A3L08_00175 a10d0e334e8011f829722285a0e474ab 417 SUPERFAMILY SSF55307 238 352 1.69E-34 T 23-10-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 A3L08_00175 a10d0e334e8011f829722285a0e474ab 417 PRINTS PR00423 Cell division protein FtsZ signature 122 142 5.7E-36 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A3L08_00175 a10d0e334e8011f829722285a0e474ab 417 PRINTS PR00423 Cell division protein FtsZ signature 158 179 5.7E-36 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A3L08_00175 a10d0e334e8011f829722285a0e474ab 417 PRINTS PR00423 Cell division protein FtsZ signature 243 264 5.7E-36 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A3L08_00175 a10d0e334e8011f829722285a0e474ab 417 PRINTS PR00423 Cell division protein FtsZ signature 220 242 5.7E-36 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A3L08_00175 a10d0e334e8011f829722285a0e474ab 417 ProSitePatterns PS01135 FtsZ protein signature 2. 121 142 - T 23-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 A3L08_00175 a10d0e334e8011f829722285a0e474ab 417 SMART SM00864 37 236 3.8E-85 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A3L08_00175 a10d0e334e8011f829722285a0e474ab 417 Gene3D G3DSA:3.40.50.1440 35 347 9.5E-99 T 23-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 A3L08_00175 a10d0e334e8011f829722285a0e474ab 417 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 33 393 33.601 T 23-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 A3L08_00175 a10d0e334e8011f829722285a0e474ab 417 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 31 357 1.6E-111 T 23-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 A3L08_00175 a10d0e334e8011f829722285a0e474ab 417 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 37 205 3.7E-44 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A3L08_01270 1c09bb1201b314d61542f954282f3178 342 Pfam PF13429 Tetratricopeptide repeat 165 249 8.4E-7 T 23-10-2018 A3L08_01270 1c09bb1201b314d61542f954282f3178 342 Gene3D G3DSA:1.25.40.10 112 335 2.4E-16 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A3L08_01270 1c09bb1201b314d61542f954282f3178 342 SUPERFAMILY SSF48452 130 327 3.8E-22 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A3L08_09525 bca5cdb249d95a63308a9ad9b89a079b 312 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L08_09525 bca5cdb249d95a63308a9ad9b89a079b 312 Gene3D G3DSA:3.40.50.300 1 239 3.4E-57 T 23-10-2018 A3L08_09525 bca5cdb249d95a63308a9ad9b89a079b 312 SUPERFAMILY SSF52540 4 225 2.09E-56 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_09525 bca5cdb249d95a63308a9ad9b89a079b 312 SMART SM00382 30 230 7.6E-11 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L08_09525 bca5cdb249d95a63308a9ad9b89a079b 312 Pfam PF00005 ABC transporter 23 165 1.2E-27 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L08_03740 6fdb69100887d9a98407ca0cd7b8b179 345 ProDom PD038575 MJECL12 PLASMID PH0156 102 325 6.0E-86 T 23-10-2018 IPR024508 Protein of unknown function DUF3226 A3L08_03740 6fdb69100887d9a98407ca0cd7b8b179 345 SUPERFAMILY SSF160945 101 337 9.81E-86 T 23-10-2018 A3L08_03740 6fdb69100887d9a98407ca0cd7b8b179 345 Gene3D G3DSA:3.40.50.10620 101 237 1.0E-64 T 23-10-2018 A3L08_03740 6fdb69100887d9a98407ca0cd7b8b179 345 Gene3D G3DSA:1.10.3490.10 238 323 1.0E-64 T 23-10-2018 A3L08_03740 6fdb69100887d9a98407ca0cd7b8b179 345 Pfam PF11536 Protein of unknown function (DUF3226) 103 339 4.3E-79 T 23-10-2018 IPR024508 Protein of unknown function DUF3226 A3L08_08640 644ebd7122bd041c9f2e1d6cb3ee4b37 928 SUPERFAMILY SSF52540 29 350 1.41E-51 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_08640 644ebd7122bd041c9f2e1d6cb3ee4b37 928 Gene3D G3DSA:3.40.50.300 2 200 1.3E-45 T 23-10-2018 A3L08_08640 644ebd7122bd041c9f2e1d6cb3ee4b37 928 SMART SM00490 259 341 1.6E-24 T 23-10-2018 IPR001650 Helicase, C-terminal A3L08_08640 644ebd7122bd041c9f2e1d6cb3ee4b37 928 Pfam PF08494 DEAD/H associated 583 750 5.1E-17 T 23-10-2018 IPR013701 DEAD/H associated GO:0005524|GO:0016818 A3L08_08640 644ebd7122bd041c9f2e1d6cb3ee4b37 928 PIRSF PIRSF037307 1 912 0.0 T 23-10-2018 IPR017170 Lhr-like ATP-dependent RNA helicase, predicted GO:0005524|GO:0016818 A3L08_08640 644ebd7122bd041c9f2e1d6cb3ee4b37 928 Gene3D G3DSA:3.40.50.300 209 372 3.3E-31 T 23-10-2018 A3L08_08640 644ebd7122bd041c9f2e1d6cb3ee4b37 928 Pfam PF00270 DEAD/DEAH box helicase 18 182 7.6E-27 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A3L08_08640 644ebd7122bd041c9f2e1d6cb3ee4b37 928 SMART SM00487 12 210 4.2E-35 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A3L08_08640 644ebd7122bd041c9f2e1d6cb3ee4b37 928 Pfam PF00271 Helicase conserved C-terminal domain 237 336 1.9E-19 T 23-10-2018 IPR001650 Helicase, C-terminal A3L08_09165 bad028587c127fda87da2633be70413f 279 Gene3D G3DSA:3.30.479.30 52 183 1.3E-51 T 23-10-2018 A3L08_09165 bad028587c127fda87da2633be70413f 279 Pfam PF01145 SPFH domain / Band 7 family 28 198 1.8E-38 T 23-10-2018 IPR001107 Band 7 domain A3L08_09165 bad028587c127fda87da2633be70413f 279 SMART SM00244 24 181 1.9E-70 T 23-10-2018 IPR001107 Band 7 domain A3L08_09165 bad028587c127fda87da2633be70413f 279 PRINTS PR00721 Stomatin signature 133 156 1.9E-73 T 23-10-2018 IPR001972 Stomatin family GO:0016020 A3L08_09165 bad028587c127fda87da2633be70413f 279 PRINTS PR00721 Stomatin signature 201 224 1.9E-73 T 23-10-2018 IPR001972 Stomatin family GO:0016020 A3L08_09165 bad028587c127fda87da2633be70413f 279 PRINTS PR00721 Stomatin signature 157 175 1.9E-73 T 23-10-2018 IPR001972 Stomatin family GO:0016020 A3L08_09165 bad028587c127fda87da2633be70413f 279 PRINTS PR00721 Stomatin signature 176 197 1.9E-73 T 23-10-2018 IPR001972 Stomatin family GO:0016020 A3L08_09165 bad028587c127fda87da2633be70413f 279 PRINTS PR00721 Stomatin signature 78 99 1.9E-73 T 23-10-2018 IPR001972 Stomatin family GO:0016020 A3L08_09165 bad028587c127fda87da2633be70413f 279 PRINTS PR00721 Stomatin signature 113 130 1.9E-73 T 23-10-2018 IPR001972 Stomatin family GO:0016020 A3L08_09165 bad028587c127fda87da2633be70413f 279 PRINTS PR00721 Stomatin signature 31 53 1.9E-73 T 23-10-2018 IPR001972 Stomatin family GO:0016020 A3L08_09165 bad028587c127fda87da2633be70413f 279 SUPERFAMILY SSF117892 55 188 6.8E-47 T 23-10-2018 IPR036013 Band 7/SPFH domain superfamily A3L08_04240 f97463066e2fc671d4955856dc81db87 121 Hamap MF_00329 50S ribosomal protein L18e [rpl18e]. 5 121 30.948 T 23-10-2018 IPR022947 Ribosomal protein L18e, archaea A3L08_04240 f97463066e2fc671d4955856dc81db87 121 Gene3D G3DSA:3.100.10.10 6 121 6.2E-41 T 23-10-2018 A3L08_04240 f97463066e2fc671d4955856dc81db87 121 ProSitePatterns PS01106 Ribosomal protein L18e signature. 36 53 - T 23-10-2018 IPR021132 Ribosomal protein L18e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_04240 f97463066e2fc671d4955856dc81db87 121 Pfam PF17135 Ribosomal protein 60S L18 and 50S L18e 12 120 6.9E-18 T 23-10-2018 IPR021131 Ribosomal protein L18e/L15P A3L08_04240 f97463066e2fc671d4955856dc81db87 121 SUPERFAMILY SSF52080 6 120 3.92E-31 T 23-10-2018 IPR036227 Ribosomal L18e/L15P superfamily A3L08_05945 9b224336a9450dcd643ef40ebaa2cf4c 334 SUPERFAMILY SSF52733 18 328 4.84E-42 T 23-10-2018 IPR036087 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like superfamily GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 A3L08_05945 9b224336a9450dcd643ef40ebaa2cf4c 334 Gene3D G3DSA:3.40.50.10210 1 333 8.5E-126 T 23-10-2018 A3L08_05945 9b224336a9450dcd643ef40ebaa2cf4c 334 Hamap MF_01086 UPF0284 protein . 1 334 136.94 T 23-10-2018 IPR002805 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, putative A3L08_05945 9b224336a9450dcd643ef40ebaa2cf4c 334 TIGRFAM TIGR00303 TIGR00303: TIGR00303 family protein 2 323 1.2E-100 T 23-10-2018 IPR002805 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, putative A3L08_08015 eccd63f431f10b2aa25063cb26b0232d 799 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 489 495 - T 23-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 A3L08_08015 eccd63f431f10b2aa25063cb26b0232d 799 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 223 794 6.1E-197 T 23-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 A3L08_08015 eccd63f431f10b2aa25063cb26b0232d 799 Gene3D G3DSA:3.40.1110.10 498 617 6.8E-100 T 23-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 A3L08_08015 eccd63f431f10b2aa25063cb26b0232d 799 SUPERFAMILY SSF55008 71 139 2.75E-22 T 23-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 A3L08_08015 eccd63f431f10b2aa25063cb26b0232d 799 TIGRFAM TIGR00003 TIGR00003: copper ion binding protein 3 66 2.5E-16 T 23-10-2018 IPR006122 Heavy metal-associated domain, copper ion-binding GO:0005507 Reactome: R-HSA-936837 A3L08_08015 eccd63f431f10b2aa25063cb26b0232d 799 TIGRFAM TIGR00003 TIGR00003: copper ion binding protein 75 135 1.3E-12 T 23-10-2018 IPR006122 Heavy metal-associated domain, copper ion-binding GO:0005507 Reactome: R-HSA-936837 A3L08_08015 eccd63f431f10b2aa25063cb26b0232d 799 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 205 795 1.2E-180 T 23-10-2018 A3L08_08015 eccd63f431f10b2aa25063cb26b0232d 799 Pfam PF00403 Heavy-metal-associated domain 75 134 7.1E-18 T 23-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 A3L08_08015 eccd63f431f10b2aa25063cb26b0232d 799 Pfam PF00403 Heavy-metal-associated domain 4 65 1.1E-16 T 23-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 A3L08_08015 eccd63f431f10b2aa25063cb26b0232d 799 SUPERFAMILY SSF81665 250 479 7.06E-14 T 23-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 A3L08_08015 eccd63f431f10b2aa25063cb26b0232d 799 Gene3D G3DSA:3.40.50.1000 468 737 6.8E-100 T 23-10-2018 IPR023214 HAD superfamily A3L08_08015 eccd63f431f10b2aa25063cb26b0232d 799 Pfam PF00122 E1-E2 ATPase 287 466 5.0E-59 T 23-10-2018 A3L08_08015 eccd63f431f10b2aa25063cb26b0232d 799 Gene3D G3DSA:3.30.70.100 71 156 3.6E-24 T 23-10-2018 A3L08_08015 eccd63f431f10b2aa25063cb26b0232d 799 Pfam PF00702 haloacid dehalogenase-like hydrolase 485 699 5.7E-43 T 23-10-2018 A3L08_08015 eccd63f431f10b2aa25063cb26b0232d 799 SUPERFAMILY SSF56784 485 792 1.7E-64 T 23-10-2018 IPR036412 HAD-like superfamily A3L08_08015 eccd63f431f10b2aa25063cb26b0232d 799 SUPERFAMILY SSF81653 290 386 6.8E-30 T 23-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 A3L08_08015 eccd63f431f10b2aa25063cb26b0232d 799 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 259 765 8.1E-106 T 23-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A3L08_08015 eccd63f431f10b2aa25063cb26b0232d 799 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 487 501 2.7E-26 T 23-10-2018 A3L08_08015 eccd63f431f10b2aa25063cb26b0232d 799 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 708 720 2.7E-26 T 23-10-2018 A3L08_08015 eccd63f431f10b2aa25063cb26b0232d 799 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 336 350 2.7E-26 T 23-10-2018 A3L08_08015 eccd63f431f10b2aa25063cb26b0232d 799 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 685 704 2.7E-26 T 23-10-2018 A3L08_08015 eccd63f431f10b2aa25063cb26b0232d 799 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 610 621 2.7E-26 T 23-10-2018 A3L08_08015 eccd63f431f10b2aa25063cb26b0232d 799 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 632 642 2.7E-26 T 23-10-2018 A3L08_08015 eccd63f431f10b2aa25063cb26b0232d 799 SUPERFAMILY SSF55008 1 67 5.89E-21 T 23-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 A3L08_08015 eccd63f431f10b2aa25063cb26b0232d 799 Gene3D G3DSA:2.70.150.20 279 391 9.2E-44 T 23-10-2018 A3L08_08015 eccd63f431f10b2aa25063cb26b0232d 799 PRINTS PR00943 Copper-transporting ATPase signature 256 275 5.8E-13 T 23-10-2018 A3L08_08015 eccd63f431f10b2aa25063cb26b0232d 799 PRINTS PR00943 Copper-transporting ATPase signature 409 423 5.8E-13 T 23-10-2018 A3L08_08015 eccd63f431f10b2aa25063cb26b0232d 799 PRINTS PR00943 Copper-transporting ATPase signature 116 136 5.8E-13 T 23-10-2018 A3L08_08015 eccd63f431f10b2aa25063cb26b0232d 799 PRINTS PR00943 Copper-transporting ATPase signature 719 733 5.8E-13 T 23-10-2018 A3L08_08015 eccd63f431f10b2aa25063cb26b0232d 799 PRINTS PR00943 Copper-transporting ATPase signature 662 679 5.8E-13 T 23-10-2018 A3L08_08015 eccd63f431f10b2aa25063cb26b0232d 799 PRINTS PR00943 Copper-transporting ATPase signature 188 206 5.8E-13 T 23-10-2018 A3L08_08015 eccd63f431f10b2aa25063cb26b0232d 799 Gene3D G3DSA:3.30.70.100 1 70 6.1E-23 T 23-10-2018 A3L08_07805 be3b6e76e1b867c715ee6bdae523eaf9 478 SUPERFAMILY SSF52935 324 478 1.96E-32 T 23-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A3L08_07805 be3b6e76e1b867c715ee6bdae523eaf9 478 PRINTS PR01050 Pyruvate kinase family signature 245 269 7.3E-65 T 23-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A3L08_07805 be3b6e76e1b867c715ee6bdae523eaf9 478 PRINTS PR01050 Pyruvate kinase family signature 270 294 7.3E-65 T 23-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A3L08_07805 be3b6e76e1b867c715ee6bdae523eaf9 478 PRINTS PR01050 Pyruvate kinase family signature 63 79 7.3E-65 T 23-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A3L08_07805 be3b6e76e1b867c715ee6bdae523eaf9 478 PRINTS PR01050 Pyruvate kinase family signature 295 313 7.3E-65 T 23-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A3L08_07805 be3b6e76e1b867c715ee6bdae523eaf9 478 PRINTS PR01050 Pyruvate kinase family signature 188 202 7.3E-65 T 23-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A3L08_07805 be3b6e76e1b867c715ee6bdae523eaf9 478 PRINTS PR01050 Pyruvate kinase family signature 218 244 7.3E-65 T 23-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A3L08_07805 be3b6e76e1b867c715ee6bdae523eaf9 478 PRINTS PR01050 Pyruvate kinase family signature 314 330 7.3E-65 T 23-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A3L08_07805 be3b6e76e1b867c715ee6bdae523eaf9 478 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 6 478 3.7E-170 T 23-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A3L08_07805 be3b6e76e1b867c715ee6bdae523eaf9 478 Pfam PF00224 Pyruvate kinase, barrel domain 6 338 2.8E-120 T 23-10-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A3L08_07805 be3b6e76e1b867c715ee6bdae523eaf9 478 Pfam PF02887 Pyruvate kinase, alpha/beta domain 368 475 3.7E-23 T 23-10-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A3L08_07805 be3b6e76e1b867c715ee6bdae523eaf9 478 Gene3D G3DSA:3.20.20.60 7 336 4.6E-167 T 23-10-2018 A3L08_07805 be3b6e76e1b867c715ee6bdae523eaf9 478 SUPERFAMILY SSF51621 4 340 5.58E-96 T 23-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 A3L08_07805 be3b6e76e1b867c715ee6bdae523eaf9 478 Gene3D G3DSA:2.40.33.10 74 170 4.6E-167 T 23-10-2018 IPR015806 Pyruvate kinase, insert domain superfamily GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A3L08_07805 be3b6e76e1b867c715ee6bdae523eaf9 478 SUPERFAMILY SSF50800 75 166 1.92E-24 T 23-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily A3L08_07805 be3b6e76e1b867c715ee6bdae523eaf9 478 Gene3D G3DSA:3.40.1380.20 337 474 4.6E-167 T 23-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A3L08_06895 339e9c344501ec9dd0eac7018b879a88 251 Hamap MF_00304 Thiamine thiazole synthase [thi4]. 2 251 44.694 T 23-10-2018 IPR022828 Thiazole biosynthetic enzyme, prokaryotic A3L08_06895 339e9c344501ec9dd0eac7018b879a88 251 Gene3D G3DSA:3.50.50.60 1 251 6.9E-102 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L08_06895 339e9c344501ec9dd0eac7018b879a88 251 PRINTS PR00419 Adrenodoxin reductase family signature 49 62 2.8E-7 T 23-10-2018 A3L08_06895 339e9c344501ec9dd0eac7018b879a88 251 PRINTS PR00419 Adrenodoxin reductase family signature 26 48 2.8E-7 T 23-10-2018 A3L08_06895 339e9c344501ec9dd0eac7018b879a88 251 Pfam PF01946 Thi4 family 8 232 6.6E-82 T 23-10-2018 A3L08_06895 339e9c344501ec9dd0eac7018b879a88 251 TIGRFAM TIGR00292 TIGR00292: thiazole biosynthesis enzyme 4 250 1.8E-95 T 23-10-2018 IPR002922 Thiazole biosynthetic enzyme Thi4 family A3L08_06895 339e9c344501ec9dd0eac7018b879a88 251 SUPERFAMILY SSF51905 5 243 1.8E-47 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L08_09230 3db378d1d4b3e71808bb96ce3cc2878b 643 Pfam PF13307 Helicase C-terminal domain 449 621 3.4E-37 T 23-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 A3L08_09230 3db378d1d4b3e71808bb96ce3cc2878b 643 Gene3D G3DSA:3.40.50.300 24 403 6.5E-116 T 23-10-2018 A3L08_09230 3db378d1d4b3e71808bb96ce3cc2878b 643 SUPERFAMILY SSF52540 6 230 4.7E-19 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_09230 3db378d1d4b3e71808bb96ce3cc2878b 643 Pfam PF06733 DEAD_2 68 238 1.4E-33 T 23-10-2018 IPR010614 DEAD2 GO:0003677|GO:0004003|GO:0005524 A3L08_09230 3db378d1d4b3e71808bb96ce3cc2878b 643 Gene3D G3DSA:1.10.275.40 234 371 6.5E-116 T 23-10-2018 A3L08_09230 3db378d1d4b3e71808bb96ce3cc2878b 643 TIGRFAM TIGR00604 rad3: DNA repair helicase (rad3) 9 630 1.9E-142 T 23-10-2018 IPR013020 ATP-dependent helicase Rad3/Chl1-like GO:0004003 A3L08_09230 3db378d1d4b3e71808bb96ce3cc2878b 643 SMART SM00487 12 270 6.2E-8 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A3L08_09230 3db378d1d4b3e71808bb96ce3cc2878b 643 Pfam PF06777 Helical and beta-bridge domain 244 435 4.0E-64 T 23-10-2018 IPR010643 Helical and beta-bridge domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167246|Reactome: R-HSA-2564830|Reactome: R-HSA-427413|Reactome: R-HSA-5696395|Reactome: R-HSA-5696400|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73863|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-77075 A3L08_09230 3db378d1d4b3e71808bb96ce3cc2878b 643 SMART SM00491 466 608 1.7E-45 T 23-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 A3L08_09230 3db378d1d4b3e71808bb96ce3cc2878b 643 SMART SM00488 7 258 1.7E-75 T 23-10-2018 IPR006554 Helicase-like, DEXD box c2 type GO:0004003|GO:0016818 A3L08_09230 3db378d1d4b3e71808bb96ce3cc2878b 643 Gene3D G3DSA:3.40.50.300 418 631 6.3E-43 T 23-10-2018 A3L08_09230 3db378d1d4b3e71808bb96ce3cc2878b 643 SUPERFAMILY SSF52540 29 602 1.59E-13 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_09230 3db378d1d4b3e71808bb96ce3cc2878b 643 Gene3D G3DSA:1.10.30.20 99 175 6.5E-116 T 23-10-2018 A3L08_06290 12728fa3a76caf038b884e4725f76861 293 Pfam PF00701 Dihydrodipicolinate synthetase family 2 289 4.4E-62 T 23-10-2018 IPR002220 DapA-like GO:0016829 A3L08_06290 12728fa3a76caf038b884e4725f76861 293 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 131 161 - T 23-10-2018 IPR020625 Schiff base-forming aldolase, active site GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 A3L08_06290 12728fa3a76caf038b884e4725f76861 293 SUPERFAMILY SSF51569 2 291 1.88E-78 T 23-10-2018 A3L08_06290 12728fa3a76caf038b884e4725f76861 293 PRINTS PR00146 Dihydrodipicolinate synthase signature 126 143 1.3E-17 T 23-10-2018 IPR002220 DapA-like GO:0016829 A3L08_06290 12728fa3a76caf038b884e4725f76861 293 PRINTS PR00146 Dihydrodipicolinate synthase signature 69 87 1.3E-17 T 23-10-2018 IPR002220 DapA-like GO:0016829 A3L08_06290 12728fa3a76caf038b884e4725f76861 293 PRINTS PR00146 Dihydrodipicolinate synthase signature 101 117 1.3E-17 T 23-10-2018 IPR002220 DapA-like GO:0016829 A3L08_06290 12728fa3a76caf038b884e4725f76861 293 PRINTS PR00146 Dihydrodipicolinate synthase signature 34 55 1.3E-17 T 23-10-2018 IPR002220 DapA-like GO:0016829 A3L08_06290 12728fa3a76caf038b884e4725f76861 293 SMART SM01130 1 292 4.1E-95 T 23-10-2018 IPR002220 DapA-like GO:0016829 A3L08_06290 12728fa3a76caf038b884e4725f76861 293 Gene3D G3DSA:3.20.20.70 1 292 1.5E-89 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L08_06290 12728fa3a76caf038b884e4725f76861 293 PIRSF PIRSF001365 1 292 4.8E-83 T 23-10-2018 IPR002220 DapA-like GO:0016829 A3L08_09540 32c65b0334bb2985c247301ec05467e0 796 SUPERFAMILY SSF52540 512 791 9.6E-82 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_09540 32c65b0334bb2985c247301ec05467e0 796 SUPERFAMILY SSF50692 2 91 3.98E-30 T 23-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily A3L08_09540 32c65b0334bb2985c247301ec05467e0 796 Gene3D G3DSA:1.10.8.60 425 506 3.7E-17 T 23-10-2018 A3L08_09540 32c65b0334bb2985c247301ec05467e0 796 SMART SM01073 8 92 4.3E-44 T 23-10-2018 IPR003338 CDC48, N-terminal subdomain A3L08_09540 32c65b0334bb2985c247301ec05467e0 796 ProSitePatterns PS00674 AAA-protein family signature. 654 672 - T 23-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 A3L08_09540 32c65b0334bb2985c247301ec05467e0 796 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 554 683 1.8E-49 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A3L08_09540 32c65b0334bb2985c247301ec05467e0 796 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 219 348 1.3E-51 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A3L08_09540 32c65b0334bb2985c247301ec05467e0 796 SMART SM01072 107 170 1.8E-18 T 23-10-2018 IPR004201 CDC48, domain 2 A3L08_09540 32c65b0334bb2985c247301ec05467e0 796 Pfam PF02359 Cell division protein 48 (CDC48), N-terminal domain 8 92 2.5E-35 T 23-10-2018 IPR003338 CDC48, N-terminal subdomain A3L08_09540 32c65b0334bb2985c247301ec05467e0 796 SMART SM00382 215 351 1.8E-25 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L08_09540 32c65b0334bb2985c247301ec05467e0 796 SMART SM00382 550 686 8.9E-25 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L08_09540 32c65b0334bb2985c247301ec05467e0 796 Gene3D G3DSA:3.40.50.300 509 683 2.2E-75 T 23-10-2018 A3L08_09540 32c65b0334bb2985c247301ec05467e0 796 Gene3D G3DSA:1.10.8.60 685 793 1.4E-34 T 23-10-2018 A3L08_09540 32c65b0334bb2985c247301ec05467e0 796 Pfam PF02933 Cell division protein 48 (CDC48), domain 2 107 169 4.7E-14 T 23-10-2018 IPR004201 CDC48, domain 2 A3L08_09540 32c65b0334bb2985c247301ec05467e0 796 Gene3D G3DSA:3.10.330.10 93 173 2.3E-7 T 23-10-2018 A3L08_09540 32c65b0334bb2985c247301ec05467e0 796 Pfam PF09336 Vps4 C terminal oligomerisation domain 750 787 5.6E-5 T 23-10-2018 IPR015415 Vps4 oligomerisation, C-terminal A3L08_09540 32c65b0334bb2985c247301ec05467e0 796 SUPERFAMILY SSF52540 179 503 1.89E-70 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_09540 32c65b0334bb2985c247301ec05467e0 796 Gene3D G3DSA:1.10.8.60 350 411 1.8E-83 T 23-10-2018 A3L08_09540 32c65b0334bb2985c247301ec05467e0 796 Gene3D G3DSA:2.40.40.20 1 92 4.3E-37 T 23-10-2018 A3L08_09540 32c65b0334bb2985c247301ec05467e0 796 TIGRFAM TIGR01243 CDC48: AAA family ATPase, CDC48 subfamily 7 794 0.0 T 23-10-2018 IPR005938 AAA ATPase, CDC48 family GO:0016787 Reactome: R-HSA-110320|Reactome: R-HSA-3371511|Reactome: R-HSA-382556|Reactome: R-HSA-532668|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5678895|Reactome: R-HSA-5689877|Reactome: R-HSA-5689896|Reactome: R-HSA-6798695|Reactome: R-HSA-8866654|Reactome: R-HSA-8876725 A3L08_09540 32c65b0334bb2985c247301ec05467e0 796 ProSitePatterns PS00674 AAA-protein family signature. 319 337 - T 23-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 A3L08_09540 32c65b0334bb2985c247301ec05467e0 796 Gene3D G3DSA:3.40.50.300 179 349 1.8E-83 T 23-10-2018 A3L08_09540 32c65b0334bb2985c247301ec05467e0 796 SUPERFAMILY SSF54585 92 184 9.81E-21 T 23-10-2018 IPR029067 CDC48 domain 2-like superfamily A3L08_08465 40b1b784c210d1a7cdf5ee560fa3833a 310 Gene3D G3DSA:3.40.50.720 8 289 1.6E-106 T 23-10-2018 A3L08_08465 40b1b784c210d1a7cdf5ee560fa3833a 310 Pfam PF01370 NAD dependent epimerase/dehydratase family 6 236 6.3E-61 T 23-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 A3L08_08465 40b1b784c210d1a7cdf5ee560fa3833a 310 Gene3D G3DSA:3.90.25.10 168 301 1.6E-106 T 23-10-2018 A3L08_08465 40b1b784c210d1a7cdf5ee560fa3833a 310 SUPERFAMILY SSF51735 1 304 3.97E-100 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L08_07845 78a8016723b953dc052fc4b68556132f 240 Gene3D G3DSA:3.40.50.300 3 239 1.2E-31 T 23-10-2018 A3L08_07845 78a8016723b953dc052fc4b68556132f 240 SUPERFAMILY SSF52540 1 225 6.94E-36 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_07845 78a8016723b953dc052fc4b68556132f 240 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 10 215 2.0E-10 T 23-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain A3L08_06385 e452000c544f12dcc80948b9ee5e28b4 475 Gene3D G3DSA:3.90.1640.30 4 236 9.0E-19 T 23-10-2018 A3L08_06385 e452000c544f12dcc80948b9ee5e28b4 475 Pfam PF02272 DHHA1 domain 328 464 7.6E-21 T 23-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 A3L08_06385 e452000c544f12dcc80948b9ee5e28b4 475 Gene3D G3DSA:3.10.310.30 336 468 7.7E-10 T 23-10-2018 A3L08_06385 e452000c544f12dcc80948b9ee5e28b4 475 SUPERFAMILY SSF64182 7 470 3.14E-63 T 23-10-2018 IPR038763 DHH phosphoesterase superfamily A3L08_03155 b8f430aa29aca3243693c45e486ff848 91 SMART SM00888 5 91 2.6E-30 T 23-10-2018 IPR014038 Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain GO:0003746|GO:0006414 Reactome: R-HSA-156842 A3L08_03155 b8f430aa29aca3243693c45e486ff848 91 PIRSF PIRSF006521 3 91 4.8E-31 T 23-10-2018 IPR004542 Translation elongation factor EF1B, beta chain, archaeal GO:0003746|GO:0006414 A3L08_03155 b8f430aa29aca3243693c45e486ff848 91 Pfam PF00736 EF-1 guanine nucleotide exchange domain 9 91 3.0E-20 T 23-10-2018 IPR014038 Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain GO:0003746|GO:0006414 Reactome: R-HSA-156842 A3L08_03155 b8f430aa29aca3243693c45e486ff848 91 Gene3D G3DSA:3.30.70.60 1 91 1.9E-34 T 23-10-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 A3L08_03155 b8f430aa29aca3243693c45e486ff848 91 Hamap MF_00043 Elongation factor 1-beta [ef1b]. 1 91 39.188 T 23-10-2018 IPR004542 Translation elongation factor EF1B, beta chain, archaeal GO:0003746|GO:0006414 A3L08_03155 b8f430aa29aca3243693c45e486ff848 91 TIGRFAM TIGR00489 aEF-1_beta: translation elongation factor aEF-1 beta 7 90 9.3E-21 T 23-10-2018 IPR004542 Translation elongation factor EF1B, beta chain, archaeal GO:0003746|GO:0006414 A3L08_03155 b8f430aa29aca3243693c45e486ff848 91 SUPERFAMILY SSF54984 9 91 3.53E-20 T 23-10-2018 IPR036219 Translation elongation factor eEF-1beta-like superfamily Reactome: R-HSA-156842 A3L08_08135 f1d3730af1c4439ec0fee3fb6d1eb227 330 Pfam PF01087 Galactose-1-phosphate uridyl transferase, N-terminal domain 2 151 6.2E-26 T 23-10-2018 IPR005849 Galactose-1-phosphate uridyl transferase, N-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 A3L08_08135 f1d3730af1c4439ec0fee3fb6d1eb227 330 PIRSF PIRSF000808 1 314 8.5E-112 T 23-10-2018 IPR001937 Galactose-1-phosphate uridyl transferase, class I GO:0008108|GO:0008270|GO:0033499 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 A3L08_08135 f1d3730af1c4439ec0fee3fb6d1eb227 330 Gene3D G3DSA:3.30.428.10 3 309 2.5E-93 T 23-10-2018 IPR036265 HIT-like superfamily A3L08_08135 f1d3730af1c4439ec0fee3fb6d1eb227 330 SUPERFAMILY SSF54197 155 314 1.86E-43 T 23-10-2018 IPR036265 HIT-like superfamily A3L08_08135 f1d3730af1c4439ec0fee3fb6d1eb227 330 SUPERFAMILY SSF54197 1 151 3.21E-46 T 23-10-2018 IPR036265 HIT-like superfamily A3L08_08135 f1d3730af1c4439ec0fee3fb6d1eb227 330 Pfam PF02744 Galactose-1-phosphate uridyl transferase, C-terminal domain 159 312 3.5E-15 T 23-10-2018 IPR005850 Galactose-1-phosphate uridyl transferase, C-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 A3L08_08135 f1d3730af1c4439ec0fee3fb6d1eb227 330 TIGRFAM TIGR00209 galT_1: galactose-1-phosphate uridylyltransferase 5 310 1.4E-53 T 23-10-2018 IPR001937 Galactose-1-phosphate uridyl transferase, class I GO:0008108|GO:0008270|GO:0033499 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 A3L08_08135 f1d3730af1c4439ec0fee3fb6d1eb227 330 Gene3D G3DSA:3.30.428.10 31 150 2.5E-93 T 23-10-2018 IPR036265 HIT-like superfamily A3L08_04865 e8b699e306b11dc90eff2ca3a4414b5a 471 SUPERFAMILY SSF56731 199 313 5.75E-11 T 23-10-2018 A3L08_04865 e8b699e306b11dc90eff2ca3a4414b5a 471 SMART SM00493 200 269 2.0E-12 T 23-10-2018 IPR006171 TOPRIM domain A3L08_04865 e8b699e306b11dc90eff2ca3a4414b5a 471 Hamap MF_00007 DNA primase DnaG [dnaG]. 36 470 36.334 T 23-10-2018 IPR020607 DNA primase DnaG, archaea GO:0000178|GO:0003896|GO:0008143 A3L08_04865 e8b699e306b11dc90eff2ca3a4414b5a 471 Pfam PF13662 Toprim domain 201 284 1.4E-12 T 23-10-2018 IPR006171 TOPRIM domain A3L08_04865 e8b699e306b11dc90eff2ca3a4414b5a 471 Gene3D G3DSA:3.40.1360.10 198 291 1.3E-12 T 23-10-2018 A3L08_03930 2a7ed825e486479365a20e8943600f16 164 Pfam PF05916 GINS complex protein 28 147 6.8E-7 T 23-10-2018 IPR021151 GINS subunit, domain A Reactome: R-HSA-176974 A3L08_03930 2a7ed825e486479365a20e8943600f16 164 Gene3D G3DSA:1.20.58.2050 1 164 1.6E-84 T 23-10-2018 IPR038437 GINS complex, subunit Psf3 superfamily Reactome: R-HSA-176974 A3L08_05770 4eb83e919bca8f666d3c562ba1551948 240 Pfam PF01522 Polysaccharide deacetylase 3 125 5.9E-19 T 23-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 A3L08_05770 4eb83e919bca8f666d3c562ba1551948 240 SUPERFAMILY SSF88713 2 230 3.06E-32 T 23-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 A3L08_05770 4eb83e919bca8f666d3c562ba1551948 240 Gene3D G3DSA:3.20.20.370 1 238 1.5E-37 T 23-10-2018 A3L08_07790 4723126001d0063c91015e4ee95a799d 160 SUPERFAMILY SSF46785 3 58 3.21E-13 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L08_07790 4723126001d0063c91015e4ee95a799d 160 Pfam PF13412 Winged helix-turn-helix DNA-binding 4 50 2.5E-14 T 23-10-2018 A3L08_07790 4723126001d0063c91015e4ee95a799d 160 Gene3D G3DSA:1.10.10.10 1 56 6.8E-24 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L08_07790 4723126001d0063c91015e4ee95a799d 160 Gene3D G3DSA:3.30.70.920 57 160 1.3E-30 T 23-10-2018 A3L08_07790 4723126001d0063c91015e4ee95a799d 160 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 4 20 7.1E-12 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L08_07790 4723126001d0063c91015e4ee95a799d 160 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 20 31 7.1E-12 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L08_07790 4723126001d0063c91015e4ee95a799d 160 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 31 50 7.1E-12 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L08_07790 4723126001d0063c91015e4ee95a799d 160 SMART SM00344 4 105 3.4E-7 T 23-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A3L08_04585 a15fff002a5c39152812b16e796858ee 118 Gene3D G3DSA:3.40.1490.10 1 118 3.8E-47 T 23-10-2018 IPR023476 Peptidyl-tRNA hydrolase II domain superfamily MetaCyc: PWY-6308 A3L08_04585 a15fff002a5c39152812b16e796858ee 118 TIGRFAM TIGR00283 arch_pth2: peptidyl-tRNA hydrolase 5 117 3.1E-42 T 23-10-2018 IPR002833 Peptidyl-tRNA hydrolase, PTH2 GO:0004045 MetaCyc: PWY-6308 A3L08_04585 a15fff002a5c39152812b16e796858ee 118 Hamap MF_00628 Peptidyl-tRNA hydrolase [pth]. 4 118 29.663 T 23-10-2018 IPR034759 Peptidyl-tRNA hydrolase, archaea GO:0004045 MetaCyc: PWY-6308 A3L08_04585 a15fff002a5c39152812b16e796858ee 118 SUPERFAMILY SSF102462 3 117 9.42E-42 T 23-10-2018 IPR023476 Peptidyl-tRNA hydrolase II domain superfamily MetaCyc: PWY-6308 A3L08_04585 a15fff002a5c39152812b16e796858ee 118 Pfam PF01981 Peptidyl-tRNA hydrolase PTH2 4 117 2.4E-43 T 23-10-2018 IPR002833 Peptidyl-tRNA hydrolase, PTH2 GO:0004045 MetaCyc: PWY-6308 A3L08_05475 87e7412c3363d359db6b774aa95eaaa9 358 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 169 326 1.9E-16 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A3L08_05475 87e7412c3363d359db6b774aa95eaaa9 358 SUPERFAMILY SSF52540 168 352 3.15E-42 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_05475 87e7412c3363d359db6b774aa95eaaa9 358 Pfam PF06858 Nucleolar GTP-binding protein 1 (NOG1) 234 291 1.0E-24 T 23-10-2018 IPR010674 Nucleolar GTP-binding protein 1, Rossman-fold domain GO:0005525 A3L08_05475 87e7412c3363d359db6b774aa95eaaa9 358 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 218 233 1.2E-13 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L08_05475 87e7412c3363d359db6b774aa95eaaa9 358 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 170 190 1.2E-13 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L08_05475 87e7412c3363d359db6b774aa95eaaa9 358 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 191 209 1.2E-13 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L08_05475 87e7412c3363d359db6b774aa95eaaa9 358 Gene3D G3DSA:1.20.120.1190 1 161 7.5E-55 T 23-10-2018 A3L08_05475 87e7412c3363d359db6b774aa95eaaa9 358 Gene3D G3DSA:3.40.50.300 162 357 1.1E-57 T 23-10-2018 A3L08_02355 5c6ecda9977c65533c716604c72a8b12 379 Hamap MF_00066 Sulfate adenylyltransferase [sat]. 26 376 50.608 T 23-10-2018 IPR020792 Sulphate adenylyltransferase, prokaryotic-type GO:0000103|GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 A3L08_02355 5c6ecda9977c65533c716604c72a8b12 379 SUPERFAMILY SSF52374 164 372 1.21E-77 T 23-10-2018 A3L08_02355 5c6ecda9977c65533c716604c72a8b12 379 Gene3D G3DSA:3.40.50.620 164 373 3.9E-90 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L08_02355 5c6ecda9977c65533c716604c72a8b12 379 Pfam PF14306 PUA-like domain 4 156 3.1E-51 T 23-10-2018 IPR025980 ATP-sulfurylase PUA-like domain KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 A3L08_02355 5c6ecda9977c65533c716604c72a8b12 379 TIGRFAM TIGR00339 sopT: sulfate adenylyltransferase 5 371 3.6E-120 T 23-10-2018 IPR002650 Sulphate adenylyltransferase GO:0000103|GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 A3L08_02355 5c6ecda9977c65533c716604c72a8b12 379 Pfam PF01747 ATP-sulfurylase 164 372 2.7E-86 T 23-10-2018 IPR024951 Sulphate adenylyltransferase catalytic domain GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 A3L08_02355 5c6ecda9977c65533c716604c72a8b12 379 SUPERFAMILY SSF88697 4 161 3.88E-49 T 23-10-2018 IPR015947 PUA-like superfamily A3L08_02355 5c6ecda9977c65533c716604c72a8b12 379 Gene3D G3DSA:3.10.400.10 1 159 5.1E-48 T 23-10-2018 A3L08_00155 15ff16d95b10a371680625d011d822bc 172 Pfam PF01472 PUA domain 89 161 4.7E-24 T 23-10-2018 IPR002478 PUA domain GO:0003723 A3L08_00155 15ff16d95b10a371680625d011d822bc 172 TIGRFAM TIGR00451 unchar_dom_2: uncharacterized domain 2 52 164 2.1E-29 T 23-10-2018 IPR004521 Uncharacterised domain CHP00451 GO:0003723 A3L08_00155 15ff16d95b10a371680625d011d822bc 172 SUPERFAMILY SSF88697 88 169 3.09E-23 T 23-10-2018 IPR015947 PUA-like superfamily A3L08_00155 15ff16d95b10a371680625d011d822bc 172 Gene3D G3DSA:3.10.450.120 1 78 1.9E-35 T 23-10-2018 A3L08_00155 15ff16d95b10a371680625d011d822bc 172 SMART SM00359 88 163 1.1E-23 T 23-10-2018 IPR002478 PUA domain GO:0003723 A3L08_00155 15ff16d95b10a371680625d011d822bc 172 PIRSF PIRSF005067 1 172 9.2E-43 T 23-10-2018 IPR016437 MCT-1/Tma20 A3L08_00155 15ff16d95b10a371680625d011d822bc 172 TIGRFAM TIGR03684 arCOG00985: arCOG04150 universal archaeal PUA-domain protein 6 169 5.6E-57 T 23-10-2018 IPR022430 Conserved hypothetical protein CHP03684 A3L08_00155 15ff16d95b10a371680625d011d822bc 172 Pfam PF09183 Domain of unknown function (DUF1947) 6 75 4.1E-6 T 23-10-2018 IPR015266 Domain of unknown function DUF1947 A3L08_00155 15ff16d95b10a371680625d011d822bc 172 Gene3D G3DSA:2.30.130.10 79 171 3.5E-35 T 23-10-2018 IPR036974 PUA domain superfamily GO:0003723 A3L08_05815 eddac34bd475ec39ae2cb8d6e8aa1f09 288 PIRSF PIRSF036979 3 286 1.7E-82 T 23-10-2018 IPR006035 Ureohydrolase GO:0046872 A3L08_05815 eddac34bd475ec39ae2cb8d6e8aa1f09 288 Gene3D G3DSA:3.40.800.10 5 286 1.7E-75 T 23-10-2018 A3L08_05815 eddac34bd475ec39ae2cb8d6e8aa1f09 288 Pfam PF00491 Arginase family 22 279 4.5E-62 T 23-10-2018 IPR006035 Ureohydrolase GO:0046872 A3L08_05815 eddac34bd475ec39ae2cb8d6e8aa1f09 288 SUPERFAMILY SSF52768 16 284 1.57E-72 T 23-10-2018 IPR023696 Ureohydrolase domain superfamily A3L08_05815 eddac34bd475ec39ae2cb8d6e8aa1f09 288 TIGRFAM TIGR01230 agmatinase: agmatinase 20 278 2.0E-69 T 23-10-2018 IPR005925 Agmatinase-related KEGG: 00330+3.5.3.11|MetaCyc: PWY-40|MetaCyc: PWY-6305|Reactome: R-HSA-351143 A3L08_04105 2d03016528a1c62699cc03324667ee41 121 Pfam PF00467 KOW motif 48 79 7.9E-10 T 23-10-2018 IPR005824 KOW A3L08_04105 2d03016528a1c62699cc03324667ee41 121 Pfam PF16906 Ribosomal proteins L26 eukaryotic, L24P archaeal 5 119 1.3E-33 T 23-10-2018 IPR005756 Ribosomal protein L26/L24, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_04105 2d03016528a1c62699cc03324667ee41 121 TIGRFAM TIGR01080 rplX_A_E: ribosomal protein uL24 6 120 4.4E-56 T 23-10-2018 IPR005756 Ribosomal protein L26/L24, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_04105 2d03016528a1c62699cc03324667ee41 121 ProSitePatterns PS01108 Ribosomal protein L24 signature. 49 66 - T 23-10-2018 IPR005825 Ribosomal protein L24/L26, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L08_04105 2d03016528a1c62699cc03324667ee41 121 SMART SM00739 45 72 4.5E-7 T 23-10-2018 IPR005824 KOW A3L08_04105 2d03016528a1c62699cc03324667ee41 121 Hamap MF_01326_A 50S ribosomal protein L24 [rplX]. 5 118 31.094 T 23-10-2018 IPR005756 Ribosomal protein L26/L24, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_04105 2d03016528a1c62699cc03324667ee41 121 SUPERFAMILY SSF50104 5 116 9.89E-38 T 23-10-2018 IPR008991 Translation protein SH3-like domain superfamily A3L08_04105 2d03016528a1c62699cc03324667ee41 121 Gene3D G3DSA:2.30.30.30 2 121 4.5E-51 T 23-10-2018 IPR014722 Ribosomal protein L2, domain 2 A3L08_01415 1b7dd938505f92c649a440206492cb05 277 Pfam PF00892 EamA-like transporter family 145 272 3.1E-13 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A3L08_01415 1b7dd938505f92c649a440206492cb05 277 Pfam PF00892 EamA-like transporter family 6 130 1.1E-17 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A3L08_01415 1b7dd938505f92c649a440206492cb05 277 SUPERFAMILY SSF103481 188 274 5.1E-7 T 23-10-2018 A3L08_01415 1b7dd938505f92c649a440206492cb05 277 SUPERFAMILY SSF103481 38 133 6.8E-14 T 23-10-2018 A3L08_08330 31cdb2feb5c5ac0c5b598a8bdcee2f2e 153 ProSitePatterns PS00201 Flavodoxin signature. 5 21 - T 23-10-2018 IPR001226 Flavodoxin, conserved site GO:0009055|GO:0010181 A3L08_08330 31cdb2feb5c5ac0c5b598a8bdcee2f2e 153 Gene3D G3DSA:3.40.50.360 1 149 1.4E-29 T 23-10-2018 IPR029039 Flavoprotein-like superfamily A3L08_08330 31cdb2feb5c5ac0c5b598a8bdcee2f2e 153 SUPERFAMILY SSF52218 2 145 8.39E-20 T 23-10-2018 IPR029039 Flavoprotein-like superfamily A3L08_02160 6adc79a6209afd9c2d37df90d75e0002 357 Pfam PF01926 50S ribosome-binding GTPase 107 162 3.8E-13 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L08_02160 6adc79a6209afd9c2d37df90d75e0002 357 SUPERFAMILY SSF52540 4 168 1.24E-39 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_02160 6adc79a6209afd9c2d37df90d75e0002 357 Gene3D G3DSA:3.40.50.300 5 162 2.4E-45 T 23-10-2018 A3L08_02160 6adc79a6209afd9c2d37df90d75e0002 357 Gene3D G3DSA:1.10.1580.10 170 252 3.4E-14 T 23-10-2018 IPR023179 GTP-binding protein, orthogonal bundle domain superfamily A3L08_09595 5db3994a7f75db32d1ba52d48f5d7c8a 187 Pfam PF00881 Nitroreductase family 8 165 6.2E-28 T 23-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 A3L08_09595 5db3994a7f75db32d1ba52d48f5d7c8a 187 SUPERFAMILY SSF55469 1 187 2.36E-46 T 23-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A3L08_09595 5db3994a7f75db32d1ba52d48f5d7c8a 187 Gene3D G3DSA:3.40.109.10 1 185 8.1E-49 T 23-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A3L08_02670 c0e31d9069eccad5c8093ad81ce98581 319 Pfam PF00005 ABC transporter 25 182 5.1E-28 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L08_02670 c0e31d9069eccad5c8093ad81ce98581 319 SMART SM00382 34 240 4.0E-10 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L08_02670 c0e31d9069eccad5c8093ad81ce98581 319 SUPERFAMILY SSF52540 5 254 1.11E-68 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_02670 c0e31d9069eccad5c8093ad81ce98581 319 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L08_02670 c0e31d9069eccad5c8093ad81ce98581 319 Gene3D G3DSA:3.40.50.300 2 319 1.4E-104 T 23-10-2018 A3L08_02670 c0e31d9069eccad5c8093ad81ce98581 319 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 234 298 6.7E-20 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A3L08_02670 c0e31d9069eccad5c8093ad81ce98581 319 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 232 318 3.7E-30 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A3L08_03205 3dcd2256aa2e42d0a60ee94318d4a1e7 302 TIGRFAM TIGR00550 nadA: quinolinate synthetase complex, A subunit 3 302 2.3E-115 T 23-10-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 A3L08_03205 3dcd2256aa2e42d0a60ee94318d4a1e7 302 Pfam PF02445 Quinolinate synthetase A protein 9 300 5.6E-111 T 23-10-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 A3L08_03205 3dcd2256aa2e42d0a60ee94318d4a1e7 302 Gene3D G3DSA:3.40.50.10800 8 282 2.1E-122 T 23-10-2018 A3L08_03205 3dcd2256aa2e42d0a60ee94318d4a1e7 302 Gene3D G3DSA:3.40.50.10800 88 300 2.1E-122 T 23-10-2018 A3L08_03205 3dcd2256aa2e42d0a60ee94318d4a1e7 302 Hamap MF_00568 Quinolinate synthase A [nadA]. 4 301 45.037 T 23-10-2018 IPR023066 Quinolinate synthase A, type 2 GO:0016765 MetaCyc: PWY-5316|MetaCyc: PWY-7342 A3L08_03205 3dcd2256aa2e42d0a60ee94318d4a1e7 302 SUPERFAMILY SSF142754 6 301 8.5E-114 T 23-10-2018 IPR036094 Quinolinate synthetase A superfamily GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 A3L08_03205 3dcd2256aa2e42d0a60ee94318d4a1e7 302 Gene3D G3DSA:3.40.50.10800 173 257 2.1E-122 T 23-10-2018 A3L08_05040 37f7ba1def1d0bef2d8d61079321ec55 905 Gene3D G3DSA:3.30.1490.180 354 418 2.3E-80 T 23-10-2018 A3L08_05040 37f7ba1def1d0bef2d8d61079321ec55 905 Pfam PF05000 RNA polymerase Rpb1, domain 4 699 804 6.3E-31 T 23-10-2018 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L08_05040 37f7ba1def1d0bef2d8d61079321ec55 905 SMART SM00663 211 515 3.1E-205 T 23-10-2018 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L08_05040 37f7ba1def1d0bef2d8d61079321ec55 905 Gene3D G3DSA:2.20.25.410 850 901 1.4E-21 T 23-10-2018 A3L08_05040 37f7ba1def1d0bef2d8d61079321ec55 905 Pfam PF04983 RNA polymerase Rpb1, domain 3 490 672 1.8E-38 T 23-10-2018 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L08_05040 37f7ba1def1d0bef2d8d61079321ec55 905 Pfam PF00623 RNA polymerase Rpb1, domain 2 321 487 1.1E-73 T 23-10-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L08_05040 37f7ba1def1d0bef2d8d61079321ec55 905 Pfam PF04998 RNA polymerase Rpb1, domain 5 811 876 4.2E-29 T 23-10-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L08_05040 37f7ba1def1d0bef2d8d61079321ec55 905 SUPERFAMILY SSF64484 4 887 0.0 T 23-10-2018 A3L08_05040 37f7ba1def1d0bef2d8d61079321ec55 905 Gene3D G3DSA:1.10.274.100 491 671 1.6E-66 T 23-10-2018 A3L08_05040 37f7ba1def1d0bef2d8d61079321ec55 905 Gene3D G3DSA:1.10.132.30 672 813 3.8E-44 T 23-10-2018 IPR038120 RNA polymerase Rpb1, funnel domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L08_05040 37f7ba1def1d0bef2d8d61079321ec55 905 TIGRFAM TIGR02390 RNA_pol_rpoA1: DNA-directed RNA polymerase subunit A' 5 894 0.0 T 23-10-2018 IPR012758 DNA-directed RNA polymerase subunit A' (Rpo1N) GO:0003677|GO:0003899|GO:0006351|GO:0008270 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L08_05040 37f7ba1def1d0bef2d8d61079321ec55 905 Gene3D G3DSA:2.40.40.20 311 482 2.3E-80 T 23-10-2018 A3L08_05040 37f7ba1def1d0bef2d8d61079321ec55 905 Gene3D G3DSA:1.20.120.1280 235 284 2.2E-11 T 23-10-2018 A3L08_05040 37f7ba1def1d0bef2d8d61079321ec55 905 Gene3D G3DSA:1.20.120.1280 1 121 2.0E-30 T 23-10-2018 A3L08_05040 37f7ba1def1d0bef2d8d61079321ec55 905 Pfam PF04997 RNA polymerase Rpb1, domain 1 6 319 7.4E-107 T 23-10-2018 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L08_05455 9f8536ba2208c5dc58bd9c6a06606118 533 SUPERFAMILY SSF52540 3 265 1.65E-120 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_05455 9f8536ba2208c5dc58bd9c6a06606118 533 SUPERFAMILY SSF52317 288 529 1.47E-80 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A3L08_05455 9f8536ba2208c5dc58bd9c6a06606118 533 Pfam PF06418 CTP synthase N-terminus 3 265 5.5E-127 T 23-10-2018 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 A3L08_05455 9f8536ba2208c5dc58bd9c6a06606118 533 TIGRFAM TIGR00337 PyrG: CTP synthase 2 525 6.4E-255 T 23-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 A3L08_05455 9f8536ba2208c5dc58bd9c6a06606118 533 Gene3D G3DSA:3.40.50.300 1 283 5.8E-139 T 23-10-2018 A3L08_05455 9f8536ba2208c5dc58bd9c6a06606118 533 Pfam PF00117 Glutamine amidotransferase class-I 300 525 4.5E-58 T 23-10-2018 IPR017926 Glutamine amidotransferase A3L08_05455 9f8536ba2208c5dc58bd9c6a06606118 533 Hamap MF_01227 CTP synthase [pyrG]. 2 530 53.09 T 23-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 A3L08_05455 9f8536ba2208c5dc58bd9c6a06606118 533 Gene3D G3DSA:3.40.50.880 284 533 2.0E-108 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A3L08_07170 f76f036ddd3fcfd137b4faac6346bdc4 570 Gene3D G3DSA:1.10.30.30 363 426 3.1E-142 T 23-10-2018 A3L08_07170 f76f036ddd3fcfd137b4faac6346bdc4 570 SUPERFAMILY SSF55681 7 478 1.34E-116 T 23-10-2018 A3L08_07170 f76f036ddd3fcfd137b4faac6346bdc4 570 Gene3D G3DSA:3.40.50.800 473 570 1.2E-32 T 23-10-2018 IPR036621 Anticodon-binding domain superfamily A3L08_07170 f76f036ddd3fcfd137b4faac6346bdc4 570 PRINTS PR01043 Glycyl-tRNA synthetase signature 27 41 1.4E-56 T 23-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A3L08_07170 f76f036ddd3fcfd137b4faac6346bdc4 570 PRINTS PR01043 Glycyl-tRNA synthetase signature 435 447 1.4E-56 T 23-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A3L08_07170 f76f036ddd3fcfd137b4faac6346bdc4 570 PRINTS PR01043 Glycyl-tRNA synthetase signature 513 532 1.4E-56 T 23-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A3L08_07170 f76f036ddd3fcfd137b4faac6346bdc4 570 PRINTS PR01043 Glycyl-tRNA synthetase signature 193 210 1.4E-56 T 23-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A3L08_07170 f76f036ddd3fcfd137b4faac6346bdc4 570 PRINTS PR01043 Glycyl-tRNA synthetase signature 210 220 1.4E-56 T 23-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A3L08_07170 f76f036ddd3fcfd137b4faac6346bdc4 570 PRINTS PR01043 Glycyl-tRNA synthetase signature 142 154 1.4E-56 T 23-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A3L08_07170 f76f036ddd3fcfd137b4faac6346bdc4 570 PRINTS PR01043 Glycyl-tRNA synthetase signature 161 178 1.4E-56 T 23-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A3L08_07170 f76f036ddd3fcfd137b4faac6346bdc4 570 SUPERFAMILY SSF52954 462 567 3.47E-33 T 23-10-2018 A3L08_07170 f76f036ddd3fcfd137b4faac6346bdc4 570 Hamap MF_00253_A Glycine--tRNA ligase [glyQS]. 6 568 47.337 T 23-10-2018 IPR022960 Glycine-tRNA ligase, archaeal GO:0004820 KEGG: 00970+6.1.1.14 A3L08_07170 f76f036ddd3fcfd137b4faac6346bdc4 570 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 158 342 4.7E-11 T 23-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L08_07170 f76f036ddd3fcfd137b4faac6346bdc4 570 Pfam PF03129 Anticodon binding domain 475 565 4.8E-24 T 23-10-2018 IPR004154 Anticodon-binding A3L08_07170 f76f036ddd3fcfd137b4faac6346bdc4 570 Gene3D G3DSA:1.20.1430.20 84 147 3.1E-142 T 23-10-2018 A3L08_07170 f76f036ddd3fcfd137b4faac6346bdc4 570 TIGRFAM TIGR00389 glyS_dimeric: glycine--tRNA ligase 7 565 2.3E-219 T 23-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A3L08_07170 f76f036ddd3fcfd137b4faac6346bdc4 570 Gene3D G3DSA:3.30.930.10 14 458 3.1E-142 T 23-10-2018 A3L08_03745 ca9cd65519a39115bd4a0ea99bb54f32 169 Pfam PF09622 Putative integral membrane protein (DUF2391) 43 163 6.7E-11 T 23-10-2018 IPR024464 Protein of unknown function DUF2391 A3L08_08060 b708b0bc1326794c049a2c69ce896f8f 106 SUPERFAMILY SSF53335 1 91 1.4E-10 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L08_08060 b708b0bc1326794c049a2c69ce896f8f 106 Gene3D G3DSA:3.40.50.150 1 84 1.3E-10 T 23-10-2018 A3L08_02420 3dd0345f8fc9792df97fa709e432db13 488 SUPERFAMILY SSF51905 9 463 1.65E-30 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L08_02420 3dd0345f8fc9792df97fa709e432db13 488 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 11 210 4.6E-9 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A3L08_02420 3dd0345f8fc9792df97fa709e432db13 488 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 419 441 2.5E-10 T 23-10-2018 A3L08_02420 3dd0345f8fc9792df97fa709e432db13 488 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 13 32 2.5E-10 T 23-10-2018 A3L08_02420 3dd0345f8fc9792df97fa709e432db13 488 Gene3D G3DSA:3.50.50.60 422 458 2.6E-6 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L08_02420 3dd0345f8fc9792df97fa709e432db13 488 Gene3D G3DSA:3.50.50.60 2 97 3.7E-20 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L08_02420 3dd0345f8fc9792df97fa709e432db13 488 PIRSF PIRSF038984 3 93 3.8E-10 T 23-10-2018 IPR028348 FAD dependent protein A3L08_02420 3dd0345f8fc9792df97fa709e432db13 488 PIRSF PIRSF038984 135 467 6.5E-25 T 23-10-2018 IPR028348 FAD dependent protein A3L08_02420 3dd0345f8fc9792df97fa709e432db13 488 Pfam PF01134 Glucose inhibited division protein A 385 461 4.5E-4 T 23-10-2018 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 A3L08_07115 012540bcfb9536e3a95b829d1a00f817 420 Gene3D G3DSA:1.20.1250.20 2 393 9.2E-36 T 23-10-2018 A3L08_07115 012540bcfb9536e3a95b829d1a00f817 420 SUPERFAMILY SSF103473 4 397 9.68E-39 T 23-10-2018 IPR036259 MFS transporter superfamily A3L08_07115 012540bcfb9536e3a95b829d1a00f817 420 PRINTS PR01988 Putative bacilysin exporter bacE signature 162 179 2.6E-8 T 23-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 A3L08_07115 012540bcfb9536e3a95b829d1a00f817 420 PRINTS PR01988 Putative bacilysin exporter bacE signature 293 316 2.6E-8 T 23-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 A3L08_07115 012540bcfb9536e3a95b829d1a00f817 420 PRINTS PR01988 Putative bacilysin exporter bacE signature 72 90 2.6E-8 T 23-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 A3L08_07115 012540bcfb9536e3a95b829d1a00f817 420 PRINTS PR01988 Putative bacilysin exporter bacE signature 135 156 2.6E-8 T 23-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 A3L08_07115 012540bcfb9536e3a95b829d1a00f817 420 Pfam PF07690 Major Facilitator Superfamily 11 354 6.7E-28 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A3L08_02900 31dc2ab175e8645dd3df49f33e0fb257 623 Gene3D G3DSA:1.10.569.10 251 445 4.8E-76 T 23-10-2018 IPR013984 Aldehyde ferredoxin oxidoreductase, domain 2 A3L08_02900 31dc2ab175e8645dd3df49f33e0fb257 623 Gene3D G3DSA:3.60.9.10 1 222 8.8E-69 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily A3L08_02900 31dc2ab175e8645dd3df49f33e0fb257 623 Gene3D G3DSA:1.10.599.10 250 607 4.8E-76 T 23-10-2018 IPR013985 Aldehyde ferredoxin oxidoreductase, domain 3 GO:0016625|GO:0051536|GO:0055114 KEGG: 00030+1.2.7.5 A3L08_02900 31dc2ab175e8645dd3df49f33e0fb257 623 SUPERFAMILY SSF48310 224 609 4.84E-87 T 23-10-2018 IPR036021 Aldehyde ferredoxin oxidoreductase-like, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 A3L08_02900 31dc2ab175e8645dd3df49f33e0fb257 623 SMART SM00790 4 219 6.6E-89 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 A3L08_02900 31dc2ab175e8645dd3df49f33e0fb257 623 SUPERFAMILY SSF56228 1 221 2.62E-55 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily A3L08_02900 31dc2ab175e8645dd3df49f33e0fb257 623 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 6 217 7.6E-60 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 A3L08_02900 31dc2ab175e8645dd3df49f33e0fb257 623 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 245 607 7.9E-79 T 23-10-2018 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 A3L08_01235 c3d267e2e981523420f2662557c936ee 171 Pfam PF05683 Fumarase C-terminus 3 171 5.9E-42 T 23-10-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 A3L08_01235 c3d267e2e981523420f2662557c936ee 171 SUPERFAMILY SSF117457 4 171 1.57E-54 T 23-10-2018 IPR036660 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain superfamily GO:0016836 A3L08_01235 c3d267e2e981523420f2662557c936ee 171 TIGRFAM TIGR00723 ttdB_fumA_fumB: hydrolyase, tartrate beta subunit/fumarate domain protein, Fe-S type 12 171 1.1E-58 T 23-10-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 A3L08_01235 c3d267e2e981523420f2662557c936ee 171 Gene3D G3DSA:3.20.130.10 1 171 1.1E-68 T 23-10-2018 IPR036660 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain superfamily GO:0016836 A3L08_07605 1be5a0a17b61d8e499de070a3780dd2d 268 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 262 3.3E-31 T 23-10-2018 A3L08_07605 1be5a0a17b61d8e499de070a3780dd2d 268 Gene3D G3DSA:3.40.50.720 1 265 2.3E-47 T 23-10-2018 A3L08_07605 1be5a0a17b61d8e499de070a3780dd2d 268 SUPERFAMILY SSF51735 12 263 4.29E-50 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L08_07605 1be5a0a17b61d8e499de070a3780dd2d 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 226 246 6.0E-16 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L08_07605 1be5a0a17b61d8e499de070a3780dd2d 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 6.0E-16 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L08_07605 1be5a0a17b61d8e499de070a3780dd2d 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 6.0E-16 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L08_07605 1be5a0a17b61d8e499de070a3780dd2d 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 150 6.0E-16 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L08_07605 1be5a0a17b61d8e499de070a3780dd2d 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 6.0E-16 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L08_07605 1be5a0a17b61d8e499de070a3780dd2d 268 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 6.0E-16 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L08_05670 c6cc19bf6a949080b0b672ce35e06886 573 SUPERFAMILY SSF55681 345 567 2.73E-43 T 23-10-2018 A3L08_05670 c6cc19bf6a949080b0b672ce35e06886 573 SUPERFAMILY SSF46955 281 352 1.92E-16 T 23-10-2018 IPR009061 Putative DNA-binding domain superfamily A3L08_05670 c6cc19bf6a949080b0b672ce35e06886 573 Gene3D G3DSA:3.30.930.10 365 568 3.3E-50 T 23-10-2018 A3L08_05670 c6cc19bf6a949080b0b672ce35e06886 573 Gene3D G3DSA:3.30.56.10 1 80 1.7E-22 T 23-10-2018 A3L08_05670 c6cc19bf6a949080b0b672ce35e06886 573 SUPERFAMILY SSF46955 5 81 4.67E-9 T 23-10-2018 IPR009061 Putative DNA-binding domain superfamily A3L08_05670 c6cc19bf6a949080b0b672ce35e06886 573 Hamap MF_00284 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 565 36.076 T 23-10-2018 IPR022918 Phenylalanine-tRNA ligase beta chain 2, bacterial/archaeal GO:0004826 KEGG: 00970+6.1.1.20 A3L08_05670 c6cc19bf6a949080b0b672ce35e06886 573 SMART SM00874 280 348 2.1E-19 T 23-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 A3L08_05670 c6cc19bf6a949080b0b672ce35e06886 573 Gene3D G3DSA:3.30.56.10 279 348 4.1E-26 T 23-10-2018 A3L08_05670 c6cc19bf6a949080b0b672ce35e06886 573 SMART SM00873 100 259 1.9E-20 T 23-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 A3L08_05670 c6cc19bf6a949080b0b672ce35e06886 573 TIGRFAM TIGR00471 pheT_arch: phenylalanine--tRNA ligase, beta subunit 1 562 4.1E-178 T 23-10-2018 IPR004531 Phenylalanyl-tRNA synthetase, class IIc, beta subunit, archae/euk cytosolic GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 A3L08_05670 c6cc19bf6a949080b0b672ce35e06886 573 SUPERFAMILY SSF56037 142 257 2.14E-5 T 23-10-2018 A3L08_05670 c6cc19bf6a949080b0b672ce35e06886 573 Pfam PF03483 B3/4 domain 119 244 4.2E-16 T 23-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 A3L08_05670 c6cc19bf6a949080b0b672ce35e06886 573 Pfam PF03484 tRNA synthetase B5 domain 284 348 2.7E-14 T 23-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 A3L08_05670 c6cc19bf6a949080b0b672ce35e06886 573 Gene3D G3DSA:3.50.40.10 81 278 8.5E-75 T 23-10-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 KEGG: 00970+6.1.1.20 A3L08_00615 9b96fc2bfd2f46fb08f38e9dc374ccb2 388 SUPERFAMILY SSF81271 309 386 9.94E-19 T 23-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 A3L08_00615 9b96fc2bfd2f46fb08f38e9dc374ccb2 388 Pfam PF02824 TGS domain 315 386 4.5E-24 T 23-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 A3L08_00615 9b96fc2bfd2f46fb08f38e9dc374ccb2 388 Pfam PF16897 C-terminal region of MMR_HSR1 domain 206 310 3.2E-18 T 23-10-2018 IPR031662 GTP binding protein, second domain A3L08_00615 9b96fc2bfd2f46fb08f38e9dc374ccb2 388 Gene3D G3DSA:3.10.20.30 311 388 8.2E-29 T 23-10-2018 IPR012675 Beta-grasp domain superfamily A3L08_00615 9b96fc2bfd2f46fb08f38e9dc374ccb2 388 SUPERFAMILY SSF52540 84 323 2.46E-51 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_00615 9b96fc2bfd2f46fb08f38e9dc374ccb2 388 Pfam PF01926 50S ribosome-binding GTPase 84 185 1.5E-21 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L08_00615 9b96fc2bfd2f46fb08f38e9dc374ccb2 388 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 85 105 3.4E-28 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L08_00615 9b96fc2bfd2f46fb08f38e9dc374ccb2 388 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 106 124 3.4E-28 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L08_00615 9b96fc2bfd2f46fb08f38e9dc374ccb2 388 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 150 168 3.4E-28 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L08_00615 9b96fc2bfd2f46fb08f38e9dc374ccb2 388 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 133 148 3.4E-28 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L08_00615 9b96fc2bfd2f46fb08f38e9dc374ccb2 388 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 83 190 2.8E-13 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A3L08_07920 a63d5e7e0bd66cf40759ee08a91db342 429 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 5 418 43.55 T 23-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 A3L08_07920 a63d5e7e0bd66cf40759ee08a91db342 429 PIRSF PIRSF000412 2 427 9.3E-145 T 23-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 A3L08_07920 a63d5e7e0bd66cf40759ee08a91db342 429 Gene3D G3DSA:3.40.640.10 38 280 5.6E-84 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A3L08_07920 a63d5e7e0bd66cf40759ee08a91db342 429 SUPERFAMILY SSF53383 5 425 1.48E-133 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A3L08_07920 a63d5e7e0bd66cf40759ee08a91db342 429 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 220 236 - T 23-10-2018 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 A3L08_07920 a63d5e7e0bd66cf40759ee08a91db342 429 Pfam PF00464 Serine hydroxymethyltransferase 10 390 2.9E-82 T 23-10-2018 IPR039429 Serine hydroxymethyltransferase-like domain KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 A3L08_07920 a63d5e7e0bd66cf40759ee08a91db342 429 Gene3D G3DSA:3.90.1150.10 281 426 3.5E-53 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A3L08_06915 e4bc807c02fcf1c84506c4bcf90091f4 197 SUPERFAMILY SSF75569 3 195 5.62E-61 T 23-10-2018 IPR036795 Inosine monophosphate cyclohydrolase-like superfamily GO:0003937|GO:0006164|GO:0006188 KEGG: 00230+3.5.4.10|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 A3L08_06915 e4bc807c02fcf1c84506c4bcf90091f4 197 Pfam PF07826 IMP cyclohydrolase-like protein 3 188 2.4E-49 T 23-10-2018 IPR020600 Inosine monophosphate cyclohydrolase-like GO:0003937|GO:0006164|GO:0006188 KEGG: 00230+3.5.4.10|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 A3L08_06915 e4bc807c02fcf1c84506c4bcf90091f4 197 TIGRFAM TIGR01922 purO_arch: IMP cyclohydrolase 3 195 4.8E-49 T 23-10-2018 IPR010191 IMP cyclohydrolase GO:0003937|GO:0006164|GO:0006188 KEGG: 00230+3.5.4.10|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 A3L08_06915 e4bc807c02fcf1c84506c4bcf90091f4 197 PIRSF PIRSF004866 2 197 1.5E-70 T 23-10-2018 IPR010191 IMP cyclohydrolase GO:0003937|GO:0006164|GO:0006188 KEGG: 00230+3.5.4.10|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 A3L08_06915 e4bc807c02fcf1c84506c4bcf90091f4 197 Hamap MF_00705 IMP cyclohydrolase [purO]. 1 197 65.1 T 23-10-2018 IPR010191 IMP cyclohydrolase GO:0003937|GO:0006164|GO:0006188 KEGG: 00230+3.5.4.10|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 A3L08_06915 e4bc807c02fcf1c84506c4bcf90091f4 197 Gene3D G3DSA:3.60.20.20 2 197 1.2E-52 T 23-10-2018 IPR036795 Inosine monophosphate cyclohydrolase-like superfamily GO:0003937|GO:0006164|GO:0006188 KEGG: 00230+3.5.4.10|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 A3L08_07970 0d8a4a9520d33ddaa52617b811e1c86f 390 SUPERFAMILY SSF111126 257 385 3.3E-18 T 23-10-2018 IPR024096 NO signalling/Golgi transport ligand-binding domain superfamily A3L08_07970 0d8a4a9520d33ddaa52617b811e1c86f 390 Pfam PF06745 KaiC 2 157 7.0E-8 T 23-10-2018 IPR014774 KaiC-like domain A3L08_07970 0d8a4a9520d33ddaa52617b811e1c86f 390 Gene3D G3DSA:3.40.50.300 1 193 1.1E-19 T 23-10-2018 A3L08_07970 0d8a4a9520d33ddaa52617b811e1c86f 390 Gene3D G3DSA:3.30.1380.20 249 389 3.5E-12 T 23-10-2018 A3L08_07970 0d8a4a9520d33ddaa52617b811e1c86f 390 SUPERFAMILY SSF52540 2 162 2.7E-13 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_07970 0d8a4a9520d33ddaa52617b811e1c86f 390 Pfam PF02830 V4R domain 338 386 2.0E-12 T 23-10-2018 IPR004096 4-vinyl reductase, 4VR A3L08_07970 0d8a4a9520d33ddaa52617b811e1c86f 390 SMART SM00989 325 387 1.2E-10 T 23-10-2018 IPR004096 4-vinyl reductase, 4VR A3L08_01385 138b0b72b4ff92508dddbac85bc5ad84 196 PIRSF PIRSF004897 1 165 1.3E-45 T 23-10-2018 IPR014424 Uncharacterised conserved protein UCP004897, ACT- type A3L08_07615 9d7fcdf72e4dda8ef7aea9f85626c438 424 Pfam PF08489 Domain of unknown function (DUF1743) 140 253 9.5E-37 T 23-10-2018 IPR013696 Domain of unknown function DUF1743 A3L08_07615 9d7fcdf72e4dda8ef7aea9f85626c438 424 Gene3D G3DSA:3.30.70.2200 1 155 2.4E-60 T 23-10-2018 A3L08_07615 9d7fcdf72e4dda8ef7aea9f85626c438 424 Pfam PF01336 OB-fold nucleic acid binding domain 270 341 6.9E-9 T 23-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 A3L08_07615 9d7fcdf72e4dda8ef7aea9f85626c438 424 Gene3D G3DSA:2.40.50.1010 252 401 2.1E-41 T 23-10-2018 A3L08_07615 9d7fcdf72e4dda8ef7aea9f85626c438 424 Hamap MF_01892 tRNA(Ile2) 2-agmatinylcytidine synthetase TiaS [tiaS]. 3 422 36.757 T 23-10-2018 IPR024913 tRNA(Ile2) 2-agmatinylcytidine synthetase TiaS GO:0002101|GO:0016879 A3L08_07615 9d7fcdf72e4dda8ef7aea9f85626c438 424 Gene3D G3DSA:3.90.600.20 156 251 2.1E-34 T 23-10-2018 A3L08_07470 e55d76f84f2459880c8159dbf2b1dbfa 592 SUPERFAMILY SSF54862 5 125 4.61E-24 T 23-10-2018 A3L08_07470 e55d76f84f2459880c8159dbf2b1dbfa 592 PRINTS PR01868 ABC transporter family E signature 151 177 8.8E-63 T 23-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 A3L08_07470 e55d76f84f2459880c8159dbf2b1dbfa 592 PRINTS PR01868 ABC transporter family E signature 104 129 8.8E-63 T 23-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 A3L08_07470 e55d76f84f2459880c8159dbf2b1dbfa 592 PRINTS PR01868 ABC transporter family E signature 49 73 8.8E-63 T 23-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 A3L08_07470 e55d76f84f2459880c8159dbf2b1dbfa 592 PRINTS PR01868 ABC transporter family E signature 76 96 8.8E-63 T 23-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 A3L08_07470 e55d76f84f2459880c8159dbf2b1dbfa 592 PRINTS PR01868 ABC transporter family E signature 21 36 8.8E-63 T 23-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 A3L08_07470 e55d76f84f2459880c8159dbf2b1dbfa 592 PRINTS PR01868 ABC transporter family E signature 135 151 8.8E-63 T 23-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 A3L08_07470 e55d76f84f2459880c8159dbf2b1dbfa 592 SMART SM00382 364 532 4.0E-10 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L08_07470 e55d76f84f2459880c8159dbf2b1dbfa 592 SMART SM00382 99 287 7.2E-10 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L08_07470 e55d76f84f2459880c8159dbf2b1dbfa 592 Gene3D G3DSA:3.40.50.300 328 590 2.4E-66 T 23-10-2018 A3L08_07470 e55d76f84f2459880c8159dbf2b1dbfa 592 Pfam PF00005 ABC transporter 361 483 2.3E-21 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L08_07470 e55d76f84f2459880c8159dbf2b1dbfa 592 Pfam PF00037 4Fe-4S binding domain 46 68 7.0E-7 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L08_07470 e55d76f84f2459880c8159dbf2b1dbfa 592 SUPERFAMILY SSF52540 339 530 1.92E-40 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_07470 e55d76f84f2459880c8159dbf2b1dbfa 592 SUPERFAMILY SSF52540 97 286 4.84E-34 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_07470 e55d76f84f2459880c8159dbf2b1dbfa 592 ProSitePatterns PS00211 ABC transporters family signature. 212 226 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L08_07470 e55d76f84f2459880c8159dbf2b1dbfa 592 Pfam PF04068 Possible Fer4-like domain in RNase L inhibitor, RLI 3 33 3.8E-11 T 23-10-2018 IPR007209 RNase L inhibitor RLI, possible metal-binding domain A3L08_07470 e55d76f84f2459880c8159dbf2b1dbfa 592 Pfam PF00005 ABC transporter 97 239 2.7E-17 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L08_07470 e55d76f84f2459880c8159dbf2b1dbfa 592 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 52 63 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L08_07470 e55d76f84f2459880c8159dbf2b1dbfa 592 Gene3D G3DSA:3.40.50.300 1 327 1.5E-103 T 23-10-2018 A3L08_01845 816305b622607d2f521d0d6baa24ccbb 445 Pfam PF00202 Aminotransferase class-III 34 438 1.0E-114 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A3L08_01845 816305b622607d2f521d0d6baa24ccbb 445 Gene3D G3DSA:3.90.1150.10 15 438 2.2E-150 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A3L08_01845 816305b622607d2f521d0d6baa24ccbb 445 Gene3D G3DSA:3.40.640.10 72 340 2.2E-150 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A3L08_01845 816305b622607d2f521d0d6baa24ccbb 445 SUPERFAMILY SSF53383 33 441 1.87E-124 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A3L08_01845 816305b622607d2f521d0d6baa24ccbb 445 PIRSF PIRSF000521 2 142 4.6E-8 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A3L08_01845 816305b622607d2f521d0d6baa24ccbb 445 PIRSF PIRSF000521 132 443 1.3E-54 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A3L08_08455 07e219f403797b2ca458575af87413c7 261 PRINTS PR00111 Alpha/beta hydrolase fold signature 85 98 4.5E-6 T 23-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A3L08_08455 07e219f403797b2ca458575af87413c7 261 PRINTS PR00111 Alpha/beta hydrolase fold signature 42 57 4.5E-6 T 23-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A3L08_08455 07e219f403797b2ca458575af87413c7 261 PRINTS PR00111 Alpha/beta hydrolase fold signature 99 112 4.5E-6 T 23-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A3L08_08455 07e219f403797b2ca458575af87413c7 261 PRINTS PR00111 Alpha/beta hydrolase fold signature 197 211 4.5E-6 T 23-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A3L08_08455 07e219f403797b2ca458575af87413c7 261 Gene3D G3DSA:3.40.50.1820 1 259 1.3E-68 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold A3L08_08455 07e219f403797b2ca458575af87413c7 261 Pfam PF12146 Serine aminopeptidase, S33 13 242 3.6E-70 T 23-10-2018 IPR022742 Serine aminopeptidase, S33 A3L08_08455 07e219f403797b2ca458575af87413c7 261 SUPERFAMILY SSF53474 10 257 1.59E-48 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold A3L08_06550 4d0601f386d9533af4b0af9dc102c353 110 Pfam PF03334 Na+/H+ antiporter subunit 10 91 4.4E-16 T 23-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 A3L08_06550 4d0601f386d9533af4b0af9dc102c353 110 TIGRFAM TIGR01300 CPA3_mnhG_phaG: monovalent cation/proton antiporter, MnhG/PhaG subunit 10 99 1.5E-21 T 23-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 A3L08_06850 b9621c3bd7cf13a0982a78e624d60f75 613 Pfam PF16286 Domain of unknown function (DUF4932) 34 209 6.1E-11 T 23-10-2018 IPR032560 Protein of unknown function DUF4932 A3L08_02610 4444b2776dcf2956aa93d6fc7ecc268d 217 TIGRFAM TIGR00309 V_ATPase_subD: V-type ATPase, D subunit 6 209 1.2E-69 T 23-10-2018 IPR002699 ATPase, V1 complex, subunit D GO:0042626 Reactome: R-HSA-1222556|Reactome: R-HSA-6798695|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A3L08_02610 4444b2776dcf2956aa93d6fc7ecc268d 217 Pfam PF01813 ATP synthase subunit D 13 206 2.2E-61 T 23-10-2018 IPR002699 ATPase, V1 complex, subunit D GO:0042626 Reactome: R-HSA-1222556|Reactome: R-HSA-6798695|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A3L08_02610 4444b2776dcf2956aa93d6fc7ecc268d 217 Hamap MF_00271 V-type ATP synthase subunit D [atpD]. 4 211 25.482 T 23-10-2018 IPR002699 ATPase, V1 complex, subunit D GO:0042626 Reactome: R-HSA-1222556|Reactome: R-HSA-6798695|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A3L08_07995 3e514e56e33a3b6aa9c42cc7d9730ddd 230 SUPERFAMILY SSF143555 12 181 3.01E-48 T 23-10-2018 A3L08_07995 3e514e56e33a3b6aa9c42cc7d9730ddd 230 Gene3D G3DSA:3.30.1330.130 3 173 1.1E-41 T 23-10-2018 A3L08_07995 3e514e56e33a3b6aa9c42cc7d9730ddd 230 Pfam PF02663 FmdE, Molybdenum formylmethanofuran dehydrogenase operon 23 165 2.8E-37 T 23-10-2018 IPR003814 Formylmethanofuran dehydrogenase, subunit E domain A3L08_07995 3e514e56e33a3b6aa9c42cc7d9730ddd 230 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 180 215 3.6E-8 T 23-10-2018 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 A3L08_07995 3e514e56e33a3b6aa9c42cc7d9730ddd 230 PIRSF PIRSF006578 3 216 5.3E-50 T 23-10-2018 IPR026328 Formylmethanofuran dehydrogenase, subunit E A3L08_05605 271a9aa0933f832978112bab69e92bf6 268 Gene3D G3DSA:3.20.20.150 1 256 1.4E-26 T 23-10-2018 A3L08_05605 271a9aa0933f832978112bab69e92bf6 268 Pfam PF01261 Xylose isomerase-like TIM barrel 29 228 2.1E-16 T 23-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain A3L08_05605 271a9aa0933f832978112bab69e92bf6 268 SUPERFAMILY SSF51658 1 239 2.62E-27 T 23-10-2018 IPR036237 Xylose isomerase-like superfamily A3L08_09740 bd1e9129183025ee25c101daa8034e51 206 Gene3D G3DSA:3.40.50.1000 1 198 8.9E-52 T 23-10-2018 IPR023214 HAD superfamily A3L08_09740 bd1e9129183025ee25c101daa8034e51 206 TIGRFAM TIGR01491 HAD-SF-IB-PSPlk: phosphoserine phosphatase-like hydrolase, archaeal 1 183 6.3E-57 T 23-10-2018 IPR006386 HAD-superfamily hydrolase, subfamily IB, PSPase-like, archaeal A3L08_09740 bd1e9129183025ee25c101daa8034e51 206 SUPERFAMILY SSF56784 2 202 4.0E-42 T 23-10-2018 IPR036412 HAD-like superfamily A3L08_09740 bd1e9129183025ee25c101daa8034e51 206 Pfam PF12710 haloacid dehalogenase-like hydrolase 5 172 5.8E-19 T 23-10-2018 A3L08_09740 bd1e9129183025ee25c101daa8034e51 206 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 4 173 4.5E-33 T 23-10-2018 A3L08_02190 dc94877279307dd2e29fe014aba6fe5e 298 Gene3D G3DSA:1.20.81.30 86 205 9.2E-7 T 23-10-2018 A3L08_02190 dc94877279307dd2e29fe014aba6fe5e 298 Pfam PF00482 Type II secretion system (T2SS), protein F 101 225 1.1E-16 T 23-10-2018 IPR018076 Type II secretion system F domain A3L08_02920 0beb78ef4424c7ce2d4bd890a076d02a 454 Pfam PF09249 tRNA nucleotidyltransferase, second domain 155 278 9.7E-39 T 23-10-2018 IPR015329 tRNA nucleotidyltransferase, substrate binding GO:0004810|GO:0016437 A3L08_02920 0beb78ef4424c7ce2d4bd890a076d02a 454 TIGRFAM TIGR03671 cca_archaeal: CCA-adding enzyme 6 418 2.5E-144 T 23-10-2018 IPR008229 tRNA nucleotidyltransferase, archaea GO:0001680|GO:0003723|GO:0004810 A3L08_02920 0beb78ef4424c7ce2d4bd890a076d02a 454 Gene3D G3DSA:3.30.460.10 16 152 4.1E-87 T 23-10-2018 A3L08_02920 0beb78ef4424c7ce2d4bd890a076d02a 454 SUPERFAMILY SSF55003 265 449 8.63E-41 T 23-10-2018 IPR011068 Nucleotidyltransferase, class I-like, C-terminal GO:0003723|GO:0016779|GO:0031123 A3L08_02920 0beb78ef4424c7ce2d4bd890a076d02a 454 SUPERFAMILY SSF81631 153 279 2.35E-37 T 23-10-2018 A3L08_02920 0beb78ef4424c7ce2d4bd890a076d02a 454 SUPERFAMILY SSF81301 1 150 6.22E-35 T 23-10-2018 A3L08_02920 0beb78ef4424c7ce2d4bd890a076d02a 454 Gene3D G3DSA:3.30.70.1550 360 399 2.4E-26 T 23-10-2018 A3L08_02920 0beb78ef4424c7ce2d4bd890a076d02a 454 Gene3D G3DSA:1.10.1410.30 9 278 4.1E-87 T 23-10-2018 A3L08_02920 0beb78ef4424c7ce2d4bd890a076d02a 454 Gene3D G3DSA:3.30.70.590 290 425 2.4E-26 T 23-10-2018 A3L08_02920 0beb78ef4424c7ce2d4bd890a076d02a 454 PIRSF PIRSF005335 1 454 2.3E-153 T 23-10-2018 IPR008229 tRNA nucleotidyltransferase, archaea GO:0001680|GO:0003723|GO:0004810 A3L08_02920 0beb78ef4424c7ce2d4bd890a076d02a 454 Pfam PF01909 Nucleotidyltransferase domain 37 141 6.6E-12 T 23-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 A3L08_02920 0beb78ef4424c7ce2d4bd890a076d02a 454 Hamap MF_01264 CCA-adding enzyme [cca]. 1 454 163.087 T 23-10-2018 IPR008229 tRNA nucleotidyltransferase, archaea GO:0001680|GO:0003723|GO:0004810 A3L08_06420 03cf909419b53abba7ff5c273c07f4b5 125 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 65 76 2.0E-18 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L08_06420 03cf909419b53abba7ff5c273c07f4b5 125 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 78 93 2.0E-18 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L08_06420 03cf909419b53abba7ff5c273c07f4b5 125 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 46 61 2.0E-18 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L08_06420 03cf909419b53abba7ff5c273c07f4b5 125 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 93 108 2.0E-18 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L08_06420 03cf909419b53abba7ff5c273c07f4b5 125 Gene3D G3DSA:1.10.10.10 11 124 3.5E-27 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L08_06420 03cf909419b53abba7ff5c273c07f4b5 125 SUPERFAMILY SSF46785 40 116 1.43E-23 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L08_06420 03cf909419b53abba7ff5c273c07f4b5 125 Pfam PF01022 Bacterial regulatory protein, arsR family 51 96 5.6E-14 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L08_06420 03cf909419b53abba7ff5c273c07f4b5 125 SMART SM00418 44 121 4.4E-27 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L08_05465 9f2d63b12d7dc1d4ea858870a5e9a610 130 Hamap MF_00029 30S ribosomal protein S8e [rps8e]. 2 126 32.591 T 23-10-2018 IPR020919 Ribosomal protein S8e, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L08_05465 9f2d63b12d7dc1d4ea858870a5e9a610 130 Pfam PF01201 Ribosomal protein S8e 2 125 2.1E-34 T 23-10-2018 IPR022309 Ribosomal protein S8e/ribosomal biogenesis NSA2 A3L08_05465 9f2d63b12d7dc1d4ea858870a5e9a610 130 ProSitePatterns PS01193 Ribosomal protein S8e signature. 10 29 - T 23-10-2018 IPR018283 Ribosomal protein S8e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_05465 9f2d63b12d7dc1d4ea858870a5e9a610 130 Gene3D G3DSA:2.40.10.310 61 130 6.6E-33 T 23-10-2018 A3L08_05465 9f2d63b12d7dc1d4ea858870a5e9a610 130 TIGRFAM TIGR00307 eS8: ribosomal protein eS8 1 127 5.9E-50 T 23-10-2018 IPR001047 Ribosomal protein S8e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_07360 bb259ddc26fdeba976595eb2a5ac4a7b 463 Pfam PF10117 McrBC 5-methylcytosine restriction system component 60 392 5.1E-49 T 23-10-2018 IPR019292 5-methylcytosine restriction system component A3L08_02985 77c711fab6b8f028992d14a589c20dbd 332 Pfam PF14258 Domain of unknown function (DUF4350) 37 107 4.2E-8 T 23-10-2018 IPR025646 Domain of unknown function DUF4350 A3L08_03350 31e7057725a471f15279145ff11ff885 333 TIGRFAM TIGR03972 rSAM_TYW1: wyosine biosynthesis protein TYW1 17 314 1.2E-129 T 23-10-2018 IPR023993 S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase, archaea GO:0008033|GO:0016829|GO:0051539 MetaCyc: PWY-7285|MetaCyc: PWY-7286 A3L08_03350 31e7057725a471f15279145ff11ff885 333 Pfam PF04055 Radical SAM superfamily 67 252 1.6E-25 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L08_03350 31e7057725a471f15279145ff11ff885 333 Hamap MF_01921 S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase [taw1]. 15 316 49.39 T 23-10-2018 IPR023993 S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase, archaea GO:0008033|GO:0016829|GO:0051539 MetaCyc: PWY-7285|MetaCyc: PWY-7286 A3L08_03350 31e7057725a471f15279145ff11ff885 333 Gene3D G3DSA:3.20.20.70 2 333 2.1E-132 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L08_03350 31e7057725a471f15279145ff11ff885 333 Pfam PF08608 Wyosine base formation 255 315 2.8E-22 T 23-10-2018 IPR013917 tRNA wybutosine-synthesis MetaCyc: PWY-7285|MetaCyc: PWY-7286 A3L08_03350 31e7057725a471f15279145ff11ff885 333 SUPERFAMILY SSF102114 65 293 1.29E-17 T 23-10-2018 A3L08_03340 377505f07c7b29724bb9b292860c8d08 389 Hamap MF_01946 Tubulin-like protein CetZ [cetZ]. 1 354 26.083 T 23-10-2018 IPR032907 Tubulin-like protein CetZ GO:0008360 A3L08_03340 377505f07c7b29724bb9b292860c8d08 389 PRINTS PR00423 Cell division protein FtsZ signature 183 205 7.2E-10 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A3L08_03340 377505f07c7b29724bb9b292860c8d08 389 PRINTS PR00423 Cell division protein FtsZ signature 123 144 7.2E-10 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A3L08_03340 377505f07c7b29724bb9b292860c8d08 389 PRINTS PR00423 Cell division protein FtsZ signature 93 113 7.2E-10 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A3L08_03340 377505f07c7b29724bb9b292860c8d08 389 SMART SM00864 2 199 3.3E-34 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A3L08_03340 377505f07c7b29724bb9b292860c8d08 389 Gene3D G3DSA:3.40.50.1440 2 362 5.8E-85 T 23-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 A3L08_03340 377505f07c7b29724bb9b292860c8d08 389 SUPERFAMILY SSF52490 3 199 4.45E-39 T 23-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 A3L08_03340 377505f07c7b29724bb9b292860c8d08 389 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 5 168 3.5E-25 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A3L08_03340 377505f07c7b29724bb9b292860c8d08 389 ProSitePatterns PS00227 Tubulin subunits alpha, beta, and gamma signature. 101 107 - T 23-10-2018 IPR017975 Tubulin, conserved site GO:0005525|GO:0005874|GO:0007017 Reactome: R-HSA-380320 A3L08_03895 658607c0f01e109a42c69f854a214610 281 SUPERFAMILY SSF54631 125 278 1.52E-31 T 23-10-2018 A3L08_03895 658607c0f01e109a42c69f854a214610 281 Pfam PF00571 CBS domain 3 55 4.9E-9 T 23-10-2018 IPR000644 CBS domain A3L08_03895 658607c0f01e109a42c69f854a214610 281 Pfam PF00571 CBS domain 224 279 2.3E-13 T 23-10-2018 IPR000644 CBS domain A3L08_03895 658607c0f01e109a42c69f854a214610 281 Pfam PF00571 CBS domain 136 181 5.0E-6 T 23-10-2018 IPR000644 CBS domain A3L08_03895 658607c0f01e109a42c69f854a214610 281 Pfam PF00571 CBS domain 67 116 1.1E-11 T 23-10-2018 IPR000644 CBS domain A3L08_03895 658607c0f01e109a42c69f854a214610 281 SUPERFAMILY SSF54631 1 118 1.26E-27 T 23-10-2018 A3L08_03895 658607c0f01e109a42c69f854a214610 281 SMART SM00116 70 118 5.3E-9 T 23-10-2018 IPR000644 CBS domain A3L08_03895 658607c0f01e109a42c69f854a214610 281 SMART SM00116 231 279 9.6E-11 T 23-10-2018 IPR000644 CBS domain A3L08_03895 658607c0f01e109a42c69f854a214610 281 SMART SM00116 136 184 0.18 T 23-10-2018 IPR000644 CBS domain A3L08_03895 658607c0f01e109a42c69f854a214610 281 SMART SM00116 10 59 1.2E-5 T 23-10-2018 IPR000644 CBS domain A3L08_03895 658607c0f01e109a42c69f854a214610 281 Gene3D G3DSA:3.10.580.10 1 122 3.6E-39 T 23-10-2018 A3L08_03895 658607c0f01e109a42c69f854a214610 281 Gene3D G3DSA:3.10.580.10 123 281 9.0E-37 T 23-10-2018 A3L08_07080 94ec0fff0e2aecd880bc0872277afd70 224 Gene3D G3DSA:1.10.150.240 17 86 2.0E-34 T 23-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 A3L08_07080 94ec0fff0e2aecd880bc0872277afd70 224 Gene3D G3DSA:3.40.50.1000 6 194 2.0E-34 T 23-10-2018 IPR023214 HAD superfamily A3L08_07080 94ec0fff0e2aecd880bc0872277afd70 224 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 103 184 5.5E-8 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L08_07080 94ec0fff0e2aecd880bc0872277afd70 224 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 123 188 2.3E-8 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L08_07080 94ec0fff0e2aecd880bc0872277afd70 224 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 2 13 1.9E-7 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L08_07080 94ec0fff0e2aecd880bc0872277afd70 224 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 152 172 1.9E-7 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L08_07080 94ec0fff0e2aecd880bc0872277afd70 224 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 179 192 1.9E-7 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L08_07080 94ec0fff0e2aecd880bc0872277afd70 224 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 101 114 1.9E-7 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L08_07080 94ec0fff0e2aecd880bc0872277afd70 224 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 190 3.4E-26 T 23-10-2018 A3L08_07080 94ec0fff0e2aecd880bc0872277afd70 224 SUPERFAMILY SSF56784 1 218 1.6E-44 T 23-10-2018 IPR036412 HAD-like superfamily A3L08_04255 f9f4acae2f3e3c2c3eeb30e94d759350 65 Pfam PF01194 RNA polymerases N / 8 kDa subunit 2 58 2.8E-30 T 23-10-2018 IPR000268 DNA-directed RNA polymerase, subunit N/Rpb10 GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A3L08_04255 f9f4acae2f3e3c2c3eeb30e94d759350 65 ProSitePatterns PS01112 RNA polymerases N / 8 Kd subunits signature. 2 11 - T 23-10-2018 IPR020789 RNA polymerases, subunit N, zinc binding site GO:0003677|GO:0003899|GO:0006351|GO:0008270 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A3L08_04255 f9f4acae2f3e3c2c3eeb30e94d759350 65 SUPERFAMILY SSF46924 2 63 7.72E-28 T 23-10-2018 IPR023580 RNA polymerase subunit RPB10 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A3L08_04255 f9f4acae2f3e3c2c3eeb30e94d759350 65 ProDom PD006539 RNA POLYMERASE DNA-DIRECTED SUBUNIT TRANSFERASE NUCLEOTIDYLTRANSFERASE METAL-BINDING ZINC TRANSCRIPTION N 10 49 3.0E-14 T 23-10-2018 IPR000268 DNA-directed RNA polymerase, subunit N/Rpb10 GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A3L08_04255 f9f4acae2f3e3c2c3eeb30e94d759350 65 Hamap MF_00250 DNA-directed RNA polymerase subunit N [rpoN]. 1 63 23.716 T 23-10-2018 IPR000268 DNA-directed RNA polymerase, subunit N/Rpb10 GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A3L08_04255 f9f4acae2f3e3c2c3eeb30e94d759350 65 Gene3D G3DSA:1.10.10.60 1 65 4.9E-33 T 23-10-2018 A3L08_04255 f9f4acae2f3e3c2c3eeb30e94d759350 65 PIRSF PIRSF005653 1 65 4.1E-32 T 23-10-2018 IPR000268 DNA-directed RNA polymerase, subunit N/Rpb10 GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A3L08_07335 2d0f5022235fe8a07f6268fd304e42ea 563 Hamap MF_00322 Type 2 DNA topoisomerase 6 subunit B [top6B]. 8 550 31.651 T 23-10-2018 IPR005734 DNA topoisomerase VI, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A3L08_07335 2d0f5022235fe8a07f6268fd304e42ea 563 Gene3D G3DSA:3.30.230.10 353 561 6.2E-72 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A3L08_07335 2d0f5022235fe8a07f6268fd304e42ea 563 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 32 130 4.8E-11 T 23-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A3L08_07335 2d0f5022235fe8a07f6268fd304e42ea 563 PIRSF PIRSF006553 1 562 8.8E-212 T 23-10-2018 IPR005734 DNA topoisomerase VI, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A3L08_07335 2d0f5022235fe8a07f6268fd304e42ea 563 ProDom PD013790 TOPOISOMERASE ISOMERASE SUBUNIT DNA B VI TYPE II NUCLEOTIDE-BINDING ATP-BINDING 353 550 5.0E-104 T 23-10-2018 IPR015320 DNA topoisomerase VI, subunit B, transducer GO:0003677|GO:0003918|GO:0006265 A3L08_07335 2d0f5022235fe8a07f6268fd304e42ea 563 SUPERFAMILY SSF54211 353 514 2.88E-61 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A3L08_07335 2d0f5022235fe8a07f6268fd304e42ea 563 Pfam PF09239 Topoisomerase VI B subunit, transducer 354 509 1.1E-56 T 23-10-2018 IPR015320 DNA topoisomerase VI, subunit B, transducer GO:0003677|GO:0003918|GO:0006265 A3L08_07335 2d0f5022235fe8a07f6268fd304e42ea 563 SUPERFAMILY SSF55874 18 229 2.1E-25 T 23-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A3L08_07335 2d0f5022235fe8a07f6268fd304e42ea 563 SMART SM00387 31 182 1.7E-8 T 23-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A3L08_07335 2d0f5022235fe8a07f6268fd304e42ea 563 Gene3D G3DSA:1.10.8.50 233 312 3.8E-9 T 23-10-2018 A3L08_07335 2d0f5022235fe8a07f6268fd304e42ea 563 TIGRFAM TIGR01052 top6b: DNA topoisomerase VI, B subunit 10 533 6.2E-228 T 23-10-2018 IPR005734 DNA topoisomerase VI, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A3L08_07335 2d0f5022235fe8a07f6268fd304e42ea 563 Gene3D G3DSA:3.30.565.10 1 232 1.1E-65 T 23-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A3L08_06415 4a77e6c47c4bf254d61724cbbc9c22ad 104 PIRSF PIRSF029904 1 102 2.4E-34 T 23-10-2018 IPR012359 NTP pyrophosphohydrolase MazG-related, YpjD A3L08_06415 4a77e6c47c4bf254d61724cbbc9c22ad 104 SUPERFAMILY SSF101386 2 95 1.74E-21 T 23-10-2018 A3L08_06415 4a77e6c47c4bf254d61724cbbc9c22ad 104 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 23 95 3.5E-16 T 23-10-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core A3L08_06415 4a77e6c47c4bf254d61724cbbc9c22ad 104 Gene3D G3DSA:1.10.287.1080 1 103 4.1E-27 T 23-10-2018 A3L08_04145 6bb5c595dd0aad673c7093c52f3f4545 201 Pfam PF17144 Ribosomal large subunit proteins 60S L5, and 50S L18 100 134 7.5E-9 T 23-10-2018 IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0008097 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_04145 6bb5c595dd0aad673c7093c52f3f4545 201 Pfam PF17144 Ribosomal large subunit proteins 60S L5, and 50S L18 6 94 1.4E-14 T 23-10-2018 IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0008097 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_04145 6bb5c595dd0aad673c7093c52f3f4545 201 Pfam PF14204 Ribosomal L18 C-terminal region 143 194 3.2E-11 T 23-10-2018 IPR025607 Ribosomal protein L5 eukaryotic/L18 archaeal, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_04145 6bb5c595dd0aad673c7093c52f3f4545 201 PRINTS PR00058 Ribosomal protein L5 signature 123 142 6.7E-10 T 23-10-2018 IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0008097 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_04145 6bb5c595dd0aad673c7093c52f3f4545 201 PRINTS PR00058 Ribosomal protein L5 signature 1 12 6.7E-10 T 23-10-2018 IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0008097 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_04145 6bb5c595dd0aad673c7093c52f3f4545 201 PRINTS PR00058 Ribosomal protein L5 signature 103 122 6.7E-10 T 23-10-2018 IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0008097 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_04145 6bb5c595dd0aad673c7093c52f3f4545 201 Gene3D G3DSA:3.30.420.100 1 197 5.2E-72 T 23-10-2018 A3L08_04145 6bb5c595dd0aad673c7093c52f3f4545 201 Hamap MF_01337_A 50S ribosomal protein L18 [rplR]. 5 192 44.991 T 23-10-2018 IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0008097 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_04145 6bb5c595dd0aad673c7093c52f3f4545 201 SUPERFAMILY SSF53137 2 195 1.81E-63 T 23-10-2018 A3L08_00250 a4924fc9b922746f132add768f4a4d54 423 Gene3D G3DSA:3.40.1710.10 42 202 5.5E-37 T 23-10-2018 A3L08_00250 a4924fc9b922746f132add768f4a4d54 423 Pfam PF12698 ABC-2 family transporter protein 19 403 2.1E-38 T 23-10-2018 A3L08_05780 42187b43774ff696728a55e747aabc78 293 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 9 274 1.2E-40 T 23-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD A3L08_05780 42187b43774ff696728a55e747aabc78 293 TIGRFAM TIGR00374 TIGR00374: TIGR00374 family protein 170 280 2.7E-20 T 23-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD A3L08_05780 42187b43774ff696728a55e747aabc78 293 TIGRFAM TIGR00374 TIGR00374: TIGR00374 family protein 11 142 4.7E-18 T 23-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD A3L08_03230 09e1e025b19b678a74040f21412d5e37 449 Gene3D G3DSA:3.40.50.2020 263 427 7.4E-143 T 23-10-2018 A3L08_03230 09e1e025b19b678a74040f21412d5e37 449 SUPERFAMILY SSF53271 239 444 9.31E-70 T 23-10-2018 IPR029057 Phosphoribosyltransferase-like A3L08_03230 09e1e025b19b678a74040f21412d5e37 449 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 4 442 45.183 T 23-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 A3L08_03230 09e1e025b19b678a74040f21412d5e37 449 Pfam PF13537 Glutamine amidotransferase domain 72 199 6.0E-19 T 23-10-2018 IPR017932 Glutamine amidotransferase type 2 domain A3L08_03230 09e1e025b19b678a74040f21412d5e37 449 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 5 443 1.9E-159 T 23-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 A3L08_03230 09e1e025b19b678a74040f21412d5e37 449 SUPERFAMILY SSF56235 5 245 4.29E-53 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A3L08_03230 09e1e025b19b678a74040f21412d5e37 449 Gene3D G3DSA:3.60.20.10 5 443 7.4E-143 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A3L08_03230 09e1e025b19b678a74040f21412d5e37 449 Pfam PF00156 Phosphoribosyl transferase domain 272 374 2.3E-8 T 23-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 A3L08_03230 09e1e025b19b678a74040f21412d5e37 449 PIRSF PIRSF000485 1 446 2.5E-158 T 23-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 A3L08_06000 6dccd3a7a780712869a908de6ff22a38 71 Gene3D G3DSA:1.20.120.330 29 70 1.4E-6 T 23-10-2018 A3L08_06000 6dccd3a7a780712869a908de6ff22a38 71 Pfam PF05168 HEPN domain 8 65 1.8E-4 T 23-10-2018 IPR007842 HEPN domain A3L08_05355 bd2242db73394e2bbb91d1bf3ec97f8d 338 SUPERFAMILY SSF56042 157 332 3.59E-47 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A3L08_05355 bd2242db73394e2bbb91d1bf3ec97f8d 338 PIRSF PIRSF005644 1 338 1.0E-123 T 23-10-2018 IPR011854 Carbamoyl dehydratase HypE A3L08_05355 bd2242db73394e2bbb91d1bf3ec97f8d 338 Gene3D G3DSA:3.90.650.10 156 338 5.4E-57 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A3L08_05355 bd2242db73394e2bbb91d1bf3ec97f8d 338 Gene3D G3DSA:3.30.1330.10 1 155 7.5E-45 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A3L08_05355 bd2242db73394e2bbb91d1bf3ec97f8d 338 SUPERFAMILY SSF55326 6 155 1.92E-33 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A3L08_05355 bd2242db73394e2bbb91d1bf3ec97f8d 338 TIGRFAM TIGR02124 hypE: hydrogenase expression/formation protein HypE 4 338 3.7E-119 T 23-10-2018 IPR011854 Carbamoyl dehydratase HypE A3L08_05355 bd2242db73394e2bbb91d1bf3ec97f8d 338 Pfam PF00586 AIR synthase related protein, N-terminal domain 42 151 3.9E-17 T 23-10-2018 IPR016188 PurM-like, N-terminal domain A3L08_05355 bd2242db73394e2bbb91d1bf3ec97f8d 338 Pfam PF02769 AIR synthase related protein, C-terminal domain 162 316 5.1E-32 T 23-10-2018 IPR010918 PurM-like, C-terminal domain A3L08_04600 2c19f6a03d4ca63dcb5494df0e60859d 170 Gene3D G3DSA:3.30.300.20 47 97 4.2E-9 T 23-10-2018 IPR015946 K homology domain-like, alpha/beta A3L08_04600 2c19f6a03d4ca63dcb5494df0e60859d 170 SUPERFAMILY SSF54814 40 96 2.22E-8 T 23-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 A3L08_04600 2c19f6a03d4ca63dcb5494df0e60859d 170 SMART SM00322 57 158 2.7E-4 T 23-10-2018 IPR004087 K Homology domain GO:0003676 A3L08_04600 2c19f6a03d4ca63dcb5494df0e60859d 170 Pfam PF13184 NusA-like KH domain 57 124 3.6E-11 T 23-10-2018 IPR025249 KH domain, NusA-like GO:0003723 A3L08_05925 067574f43b951ec390445896e1bab932 179 SUPERFAMILY SSF53448 2 174 2.48E-21 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L08_05925 067574f43b951ec390445896e1bab932 179 Gene3D G3DSA:3.90.550.10 2 176 1.5E-29 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L08_05925 067574f43b951ec390445896e1bab932 179 Pfam PF12804 MobA-like NTP transferase domain 3 116 4.4E-17 T 23-10-2018 IPR025877 MobA-like NTP transferase A3L08_02455 a5f3c4603f65e4baabe32b2d3a6e2eea 516 PRINTS PR00175 Sodium/alanine symporter signature 480 500 6.0E-55 T 23-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A3L08_02455 a5f3c4603f65e4baabe32b2d3a6e2eea 516 PRINTS PR00175 Sodium/alanine symporter signature 244 262 6.0E-55 T 23-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A3L08_02455 a5f3c4603f65e4baabe32b2d3a6e2eea 516 PRINTS PR00175 Sodium/alanine symporter signature 363 381 6.0E-55 T 23-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A3L08_02455 a5f3c4603f65e4baabe32b2d3a6e2eea 516 PRINTS PR00175 Sodium/alanine symporter signature 272 291 6.0E-55 T 23-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A3L08_02455 a5f3c4603f65e4baabe32b2d3a6e2eea 516 PRINTS PR00175 Sodium/alanine symporter signature 408 430 6.0E-55 T 23-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A3L08_02455 a5f3c4603f65e4baabe32b2d3a6e2eea 516 PRINTS PR00175 Sodium/alanine symporter signature 92 114 6.0E-55 T 23-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A3L08_02455 a5f3c4603f65e4baabe32b2d3a6e2eea 516 ProSitePatterns PS00873 Sodium:alanine symporter family signature. 92 107 - T 23-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A3L08_02455 a5f3c4603f65e4baabe32b2d3a6e2eea 516 TIGRFAM TIGR00835 agcS: amino acid carrier protein 206 511 3.8E-93 T 23-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A3L08_02455 a5f3c4603f65e4baabe32b2d3a6e2eea 516 Gene3D G3DSA:1.20.1740.10 199 514 3.8E-8 T 23-10-2018 A3L08_02455 a5f3c4603f65e4baabe32b2d3a6e2eea 516 Pfam PF01235 Sodium:alanine symporter family 55 188 3.4E-36 T 23-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A3L08_02455 a5f3c4603f65e4baabe32b2d3a6e2eea 516 Pfam PF01235 Sodium:alanine symporter family 204 513 5.2E-99 T 23-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 A3L08_09245 aea32f0713bd0c6f20ee6d8e4b70f383 348 SUPERFAMILY SSF53187 4 344 2.17E-71 T 23-10-2018 A3L08_09245 aea32f0713bd0c6f20ee6d8e4b70f383 348 SUPERFAMILY SSF101821 68 177 3.21E-29 T 23-10-2018 A3L08_09245 aea32f0713bd0c6f20ee6d8e4b70f383 348 PIRSF PIRSF001123 1 348 1.5E-121 T 23-10-2018 IPR008007 Peptidase M42 A3L08_09245 aea32f0713bd0c6f20ee6d8e4b70f383 348 Gene3D G3DSA:3.40.630.10 6 336 6.1E-136 T 23-10-2018 A3L08_09245 aea32f0713bd0c6f20ee6d8e4b70f383 348 Pfam PF05343 M42 glutamyl aminopeptidase 45 335 2.5E-111 T 23-10-2018 IPR008007 Peptidase M42 A3L08_09245 aea32f0713bd0c6f20ee6d8e4b70f383 348 Gene3D G3DSA:2.40.30.40 68 161 6.1E-136 T 23-10-2018 IPR023367 Peptidase M42, domain 2 A3L08_08740 7392098e625c0cbad6edf829b2df9ca5 515 TIGRFAM TIGR00284 TIGR00284: dihydropteroate synthase-related protein 6 504 5.2E-97 T 23-10-2018 IPR005236 Dihydropteroate synthase-related protein synthase-related protein A3L08_08740 7392098e625c0cbad6edf829b2df9ca5 515 Pfam PF00809 Pterin binding enzyme 173 239 7.1E-7 T 23-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A3L08_08740 7392098e625c0cbad6edf829b2df9ca5 515 SUPERFAMILY SSF51717 161 386 8.63E-26 T 23-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A3L08_00300 02e0dfcfca091a0eb726d644adec16c3 724 Gene3D G3DSA:3.40.190.10 213 548 1.5E-44 T 23-10-2018 A3L08_00300 02e0dfcfca091a0eb726d644adec16c3 724 Gene3D G3DSA:3.10.105.10 555 719 1.3E-41 T 23-10-2018 A3L08_00300 02e0dfcfca091a0eb726d644adec16c3 724 Gene3D G3DSA:3.40.190.10 188 198 8.0E-6 T 23-10-2018 A3L08_00300 02e0dfcfca091a0eb726d644adec16c3 724 SUPERFAMILY SSF53850 130 212 3.44E-8 T 23-10-2018 A3L08_00300 02e0dfcfca091a0eb726d644adec16c3 724 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 277 713 1.4E-65 T 23-10-2018 IPR000914 Solute-binding protein family 5 domain A3L08_00300 02e0dfcfca091a0eb726d644adec16c3 724 Gene3D G3DSA:3.10.105.10 113 187 8.0E-6 T 23-10-2018 A3L08_00300 02e0dfcfca091a0eb726d644adec16c3 724 SUPERFAMILY SSF53850 231 712 7.31E-84 T 23-10-2018 A3L08_00300 02e0dfcfca091a0eb726d644adec16c3 724 PIRSF PIRSF002741 1 71 27.0 T 23-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 A3L08_00300 02e0dfcfca091a0eb726d644adec16c3 724 PIRSF PIRSF002741 211 433 8.6E-10 T 23-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 A3L08_00300 02e0dfcfca091a0eb726d644adec16c3 724 PIRSF PIRSF002741 116 215 4.5E-5 T 23-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 A3L08_00300 02e0dfcfca091a0eb726d644adec16c3 724 PIRSF PIRSF002741 447 718 4.0E-52 T 23-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 A3L08_01355 9719a7aeca895bded8bcbfc9722c43d3 181 SMART SM00531 19 158 1.4E-54 T 23-10-2018 IPR002853 Transcription initiation factor IIE subunit alpha, N-terminal GO:0006367 Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-674695|Reactome: R-HSA-6807505|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-76042 A3L08_01355 9719a7aeca895bded8bcbfc9722c43d3 181 Hamap MF_01909 Transcription factor E [tfe]. 3 166 26.607 T 23-10-2018 IPR016481 Transcription factor TFE, archaea GO:0006355 A3L08_01355 9719a7aeca895bded8bcbfc9722c43d3 181 Gene3D G3DSA:1.10.10.10 4 87 2.7E-27 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L08_01355 9719a7aeca895bded8bcbfc9722c43d3 181 TIGRFAM TIGR00373 TIGR00373: transcription factor E 11 165 1.0E-47 T 23-10-2018 IPR016481 Transcription factor TFE, archaea GO:0006355 A3L08_01355 9719a7aeca895bded8bcbfc9722c43d3 181 SUPERFAMILY SSF46785 6 87 5.57E-24 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L08_01355 9719a7aeca895bded8bcbfc9722c43d3 181 PIRSF PIRSF006373 1 179 2.0E-70 T 23-10-2018 IPR016481 Transcription factor TFE, archaea GO:0006355 A3L08_01355 9719a7aeca895bded8bcbfc9722c43d3 181 Pfam PF02002 TFIIE alpha subunit 11 110 2.9E-24 T 23-10-2018 IPR024550 TFIIEalpha/SarR/Rpc3 HTH domain Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-674695|Reactome: R-HSA-6807505|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-76042 A3L08_06360 fa171c522ce5b07fdc226873a249b91a 386 Pfam PF04412 Protein of unknown function (DUF521) 1 383 4.6E-148 T 23-10-2018 IPR007506 Aconitase X catalytic domain, putative A3L08_08250 969765bbdb87edf9933bb88f7a7d2bf5 115 Gene3D G3DSA:2.60.40.730 1 115 1.3E-51 T 23-10-2018 IPR036073 Desulfoferrodoxin, ferrous iron-binding domain superfamily GO:0005506|GO:0016491|GO:0055114 A3L08_08250 969765bbdb87edf9933bb88f7a7d2bf5 115 SUPERFAMILY SSF49367 5 114 4.19E-40 T 23-10-2018 IPR036073 Desulfoferrodoxin, ferrous iron-binding domain superfamily GO:0005506|GO:0016491|GO:0055114 A3L08_08250 969765bbdb87edf9933bb88f7a7d2bf5 115 TIGRFAM TIGR00332 neela_ferrous: desulfoferrodoxin ferrous iron-binding domain 8 114 1.1E-35 T 23-10-2018 IPR002742 Desulfoferrodoxin, ferrous iron-binding domain GO:0005506|GO:0016491|GO:0055114 A3L08_08250 969765bbdb87edf9933bb88f7a7d2bf5 115 Pfam PF01880 Desulfoferrodoxin 9 111 9.1E-33 T 23-10-2018 IPR002742 Desulfoferrodoxin, ferrous iron-binding domain GO:0005506|GO:0016491|GO:0055114 A3L08_09105 988cc44f336432ae0093fa2b01d1245b 144 PIRSF PIRSF006595 1 144 5.6E-50 T 23-10-2018 IPR005369 Uncharacterised protein family UPF0179 A3L08_09105 988cc44f336432ae0093fa2b01d1245b 144 Hamap MF_00498 UPF0179 protein . 2 141 23.894 T 23-10-2018 IPR005369 Uncharacterised protein family UPF0179 A3L08_09105 988cc44f336432ae0093fa2b01d1245b 144 ProDom PD016182 UPF0179 TK0790 TV1250 PAE0681 PF1381 AF2154 MA3685 VNG1401C MJ1627 PH1477 3 143 2.0E-67 T 23-10-2018 IPR005369 Uncharacterised protein family UPF0179 A3L08_09105 988cc44f336432ae0093fa2b01d1245b 144 Pfam PF03684 Uncharacterised protein family (UPF0179) 4 139 8.7E-43 T 23-10-2018 IPR005369 Uncharacterised protein family UPF0179 A3L08_06695 d3ccfa45aea455e838d25bcb8efb9d1b 483 Gene3D G3DSA:3.30.930.10 13 284 1.4E-85 T 23-10-2018 A3L08_06695 d3ccfa45aea455e838d25bcb8efb9d1b 483 Gene3D G3DSA:3.40.50.800 285 403 5.7E-36 T 23-10-2018 IPR036621 Anticodon-binding domain superfamily A3L08_06695 d3ccfa45aea455e838d25bcb8efb9d1b 483 Pfam PF09180 Prolyl-tRNA synthetase, C-terminal 413 483 4.5E-18 T 23-10-2018 IPR016061 Proline-tRNA ligase, class II, C-terminal GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 A3L08_06695 d3ccfa45aea455e838d25bcb8efb9d1b 483 SUPERFAMILY SSF64586 407 483 1.96E-22 T 23-10-2018 IPR017449 Prolyl-tRNA synthetase, class II GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 A3L08_06695 d3ccfa45aea455e838d25bcb8efb9d1b 483 Hamap MF_01571 Proline--tRNA ligase [proS]. 7 483 41.37 T 23-10-2018 IPR004499 Proline-tRNA ligase, class IIa, archaeal-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 A3L08_06695 d3ccfa45aea455e838d25bcb8efb9d1b 483 Gene3D G3DSA:3.30.110.30 406 482 3.6E-20 T 23-10-2018 IPR017449 Prolyl-tRNA synthetase, class II GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 A3L08_06695 d3ccfa45aea455e838d25bcb8efb9d1b 483 SMART SM00946 412 483 1.8E-26 T 23-10-2018 IPR016061 Proline-tRNA ligase, class II, C-terminal GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 A3L08_06695 d3ccfa45aea455e838d25bcb8efb9d1b 483 TIGRFAM TIGR00408 proS_fam_I: proline--tRNA ligase 11 483 1.5E-180 T 23-10-2018 IPR004499 Proline-tRNA ligase, class IIa, archaeal-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 A3L08_06695 d3ccfa45aea455e838d25bcb8efb9d1b 483 Pfam PF03129 Anticodon binding domain 291 385 5.2E-23 T 23-10-2018 IPR004154 Anticodon-binding A3L08_06695 d3ccfa45aea455e838d25bcb8efb9d1b 483 SUPERFAMILY SSF55681 12 278 1.32E-75 T 23-10-2018 A3L08_06695 d3ccfa45aea455e838d25bcb8efb9d1b 483 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 101 273 1.7E-24 T 23-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L08_06695 d3ccfa45aea455e838d25bcb8efb9d1b 483 PRINTS PR01046 Prolyl-tRNA synthetase signature 137 145 2.1E-12 T 23-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 A3L08_06695 d3ccfa45aea455e838d25bcb8efb9d1b 483 PRINTS PR01046 Prolyl-tRNA synthetase signature 66 84 2.1E-12 T 23-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 A3L08_06695 d3ccfa45aea455e838d25bcb8efb9d1b 483 PRINTS PR01046 Prolyl-tRNA synthetase signature 147 158 2.1E-12 T 23-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 A3L08_06695 d3ccfa45aea455e838d25bcb8efb9d1b 483 PRINTS PR01046 Prolyl-tRNA synthetase signature 107 118 2.1E-12 T 23-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 A3L08_06695 d3ccfa45aea455e838d25bcb8efb9d1b 483 SUPERFAMILY SSF52954 279 404 3.78E-37 T 23-10-2018 A3L08_05610 7256f8d9fc25d5be682c34d10439ebd9 332 Pfam PF01343 Peptidase family S49 147 295 1.7E-39 T 23-10-2018 IPR002142 Peptidase S49 GO:0006508|GO:0008233 A3L08_05610 7256f8d9fc25d5be682c34d10439ebd9 332 TIGRFAM TIGR00706 SppA_dom: signal peptide peptidase SppA, 36K type 88 291 1.1E-67 T 23-10-2018 IPR004635 Peptidase S49, SppA GO:0006508|GO:0008233 A3L08_05610 7256f8d9fc25d5be682c34d10439ebd9 332 Gene3D G3DSA:3.40.1750.20 186 252 1.1E-53 T 23-10-2018 A3L08_05610 7256f8d9fc25d5be682c34d10439ebd9 332 Gene3D G3DSA:3.90.226.10 91 287 1.1E-53 T 23-10-2018 A3L08_05610 7256f8d9fc25d5be682c34d10439ebd9 332 SUPERFAMILY SSF52096 82 280 1.99E-38 T 23-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A3L08_04020 f549502bc6d6a3d5990cb11dff0b9ba6 385 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 202 222 - T 23-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site A3L08_04020 f549502bc6d6a3d5990cb11dff0b9ba6 385 Gene3D G3DSA:3.90.1150.10 25 379 3.3E-137 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A3L08_04020 f549502bc6d6a3d5990cb11dff0b9ba6 385 Gene3D G3DSA:3.40.640.10 35 280 3.3E-137 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A3L08_04020 f549502bc6d6a3d5990cb11dff0b9ba6 385 PIRSF PIRSF000524 17 385 4.4E-102 T 23-10-2018 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832|Reactome: R-HSA-389661|Reactome: R-HSA-9033241 A3L08_04020 f549502bc6d6a3d5990cb11dff0b9ba6 385 SUPERFAMILY SSF53383 22 383 1.48E-97 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A3L08_04020 f549502bc6d6a3d5990cb11dff0b9ba6 385 Pfam PF00266 Aminotransferase class-V 45 370 1.4E-41 T 23-10-2018 IPR000192 Aminotransferase class V domain A3L08_00780 140790c6dd02dacb2db98df99bc45e02 264 TIGRFAM TIGR00522 dph5: diphthine synthase 3 256 4.0E-105 T 23-10-2018 IPR004551 Diphthine synthase GO:0004164|GO:0017183 Reactome: R-HSA-5358493 A3L08_00780 140790c6dd02dacb2db98df99bc45e02 264 Gene3D G3DSA:3.40.1010.10 1 114 1.1E-41 T 23-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 A3L08_00780 140790c6dd02dacb2db98df99bc45e02 264 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 3 213 1.0E-21 T 23-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 A3L08_00780 140790c6dd02dacb2db98df99bc45e02 264 Gene3D G3DSA:3.30.950.10 115 264 1.8E-53 T 23-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 A3L08_00780 140790c6dd02dacb2db98df99bc45e02 264 PIRSF PIRSF036432 2 260 2.4E-99 T 23-10-2018 IPR004551 Diphthine synthase GO:0004164|GO:0017183 Reactome: R-HSA-5358493 A3L08_00780 140790c6dd02dacb2db98df99bc45e02 264 SUPERFAMILY SSF53790 1 259 2.49E-63 T 23-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 A3L08_00780 140790c6dd02dacb2db98df99bc45e02 264 Hamap MF_01084 Diphthine synthase [dphB]. 2 256 36.524 T 23-10-2018 IPR004551 Diphthine synthase GO:0004164|GO:0017183 Reactome: R-HSA-5358493 A3L08_01965 2b3f20429c53590d0a71e52cbe01e415 278 Hamap MF_00361 NAD kinase [nadK]. 1 278 30.484 T 23-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 A3L08_01965 2b3f20429c53590d0a71e52cbe01e415 278 Pfam PF01513 ATP-NAD kinase 2 261 2.3E-72 T 23-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 A3L08_01965 2b3f20429c53590d0a71e52cbe01e415 278 Gene3D G3DSA:3.40.50.10330 20 267 4.3E-70 T 23-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 A3L08_01965 2b3f20429c53590d0a71e52cbe01e415 278 SUPERFAMILY SSF111331 3 270 6.41E-72 T 23-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily A3L08_01965 2b3f20429c53590d0a71e52cbe01e415 278 Gene3D G3DSA:2.60.200.30 121 254 4.3E-70 T 23-10-2018 IPR017437 ATP-NAD kinase, PpnK-type, C-terminal GO:0003951|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 A3L08_07415 15bfbcf3679b28153f75e2f72e646092 211 Gene3D G3DSA:3.90.320.10 10 208 4.9E-24 T 23-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal A3L08_07415 15bfbcf3679b28153f75e2f72e646092 211 Pfam PF12705 PD-(D/E)XK nuclease superfamily 62 206 4.2E-6 T 23-10-2018 IPR038726 PD-(D/E)XK endonuclease-like domain, AddAB-type A3L08_07415 15bfbcf3679b28153f75e2f72e646092 211 TIGRFAM TIGR00372 cas4: CRISPR-associated protein Cas4 14 208 9.3E-30 T 23-10-2018 IPR013343 CRISPR-associated protein Cas4 A3L08_05220 2ba278a5c13a617c0eb1a1ef40f7855d 299 Gene3D G3DSA:1.20.1510.10 11 205 8.9E-49 T 23-10-2018 IPR027469 Cation efflux transmembrane domain superfamily A3L08_05220 2ba278a5c13a617c0eb1a1ef40f7855d 299 SUPERFAMILY SSF160240 209 282 2.62E-15 T 23-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 A3L08_05220 2ba278a5c13a617c0eb1a1ef40f7855d 299 Pfam PF01545 Cation efflux family 16 205 3.6E-50 T 23-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 A3L08_05220 2ba278a5c13a617c0eb1a1ef40f7855d 299 Gene3D G3DSA:3.30.70.1350 206 284 8.7E-8 T 23-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 A3L08_05220 2ba278a5c13a617c0eb1a1ef40f7855d 299 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 13 284 1.8E-92 T 23-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 A3L08_05220 2ba278a5c13a617c0eb1a1ef40f7855d 299 Pfam PF16916 Dimerisation domain of Zinc Transporter 214 282 2.1E-11 T 23-10-2018 IPR027470 Cation efflux protein, cytoplasmic domain A3L08_05220 2ba278a5c13a617c0eb1a1ef40f7855d 299 SUPERFAMILY SSF161111 11 206 8.89E-59 T 23-10-2018 IPR027469 Cation efflux transmembrane domain superfamily A3L08_05975 1b92de7d85357dc24cbc2c0f7d9ab813 241 Pfam PF01588 Putative tRNA binding domain 138 224 1.3E-18 T 23-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 A3L08_05975 1b92de7d85357dc24cbc2c0f7d9ab813 241 Gene3D G3DSA:2.40.50.140 125 241 2.0E-35 T 23-10-2018 A3L08_05975 1b92de7d85357dc24cbc2c0f7d9ab813 241 Gene3D G3DSA:1.20.1440.150 1 124 8.9E-58 T 23-10-2018 A3L08_05975 1b92de7d85357dc24cbc2c0f7d9ab813 241 SUPERFAMILY SSF50249 134 223 1.62E-16 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L08_08865 c9fcfbfd15839eecfc63fb21622d6ace 167 Pfam PF01936 NYN domain 29 160 4.4E-21 T 23-10-2018 IPR021139 NYN domain, limkain-b1-type A3L08_08865 c9fcfbfd15839eecfc63fb21622d6ace 167 TIGRFAM TIGR00288 TIGR00288: TIGR00288 family protein 22 161 8.4E-65 T 23-10-2018 IPR002790 Conserved hypothetical protein CHP00288 A3L08_08865 c9fcfbfd15839eecfc63fb21622d6ace 167 ProDom PD010896 FAMILY DUF88 ARCHAEBACTERIAL PROTEIN MJ0482 PH0073 PF2040 VNG1608C MA3857 PF2039 28 101 4.0E-31 T 23-10-2018 A3L08_08865 c9fcfbfd15839eecfc63fb21622d6ace 167 Gene3D G3DSA:3.40.50.1010 19 162 4.0E-12 T 23-10-2018 A3L08_08555 dbb19d6878ea7db529f7f3d4deaedf96 153 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 10 149 3.9E-27 T 23-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 A3L08_08555 dbb19d6878ea7db529f7f3d4deaedf96 153 SUPERFAMILY SSF55620 10 148 3.5E-34 T 23-10-2018 A3L08_08555 dbb19d6878ea7db529f7f3d4deaedf96 153 Gene3D G3DSA:3.30.479.10 11 150 7.4E-32 T 23-10-2018 IPR038418 6-pyruvoyl tetrahydropterin synthase/QueD superfamily Reactome: R-HSA-1474151 A3L08_03855 a80c2c19e577d8a48433c6e7b5d9b171 256 Hamap MF_00623 Exosome complex component Rrp4 [rrp4]. 7 235 39.549 T 23-10-2018 IPR023474 Exosome complex component Rrp4 GO:0000178|GO:0008143 A3L08_03855 a80c2c19e577d8a48433c6e7b5d9b171 256 SUPERFAMILY SSF54791 148 228 3.29E-18 T 23-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 A3L08_03855 a80c2c19e577d8a48433c6e7b5d9b171 256 SMART SM00316 63 137 1.6E-7 T 23-10-2018 IPR022967 RNA-binding domain, S1 A3L08_03855 a80c2c19e577d8a48433c6e7b5d9b171 256 SUPERFAMILY SSF110324 3 58 1.23E-13 T 23-10-2018 A3L08_03855 a80c2c19e577d8a48433c6e7b5d9b171 256 Pfam PF15985 KH domain 149 195 3.6E-9 T 23-10-2018 IPR004088 K Homology domain, type 1 GO:0003723 A3L08_03855 a80c2c19e577d8a48433c6e7b5d9b171 256 SUPERFAMILY SSF50249 59 152 4.03E-18 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L08_03855 a80c2c19e577d8a48433c6e7b5d9b171 256 Pfam PF14382 Exosome complex exonuclease RRP4 N-terminal region 11 46 3.2E-7 T 23-10-2018 IPR025721 Exosome complex component, N-terminal domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A3L08_03855 a80c2c19e577d8a48433c6e7b5d9b171 256 Gene3D G3DSA:3.30.1370.10 149 235 1.1E-33 T 23-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 A3L08_03855 a80c2c19e577d8a48433c6e7b5d9b171 256 Gene3D G3DSA:2.40.50.100 1 57 8.5E-22 T 23-10-2018 A3L08_03855 a80c2c19e577d8a48433c6e7b5d9b171 256 SMART SM00322 146 211 2.5E-7 T 23-10-2018 IPR004087 K Homology domain GO:0003676 A3L08_03855 a80c2c19e577d8a48433c6e7b5d9b171 256 Gene3D G3DSA:2.40.50.140 58 141 2.5E-20 T 23-10-2018 A3L08_03575 6dfda6e7d057a8b9be0459a3d36d377d 125 Pfam PF01092 Ribosomal protein S6e 4 123 2.4E-35 T 23-10-2018 IPR001377 Ribosomal protein S6e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-166208|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_03575 6dfda6e7d057a8b9be0459a3d36d377d 125 Hamap MF_00512 30S ribosomal protein S6e [rps6e]. 2 125 18.272 T 23-10-2018 IPR020924 Ribosomal protein S6e, archaeal GO:0003735|GO:0005840|GO:0006412 A3L08_03575 6dfda6e7d057a8b9be0459a3d36d377d 125 SMART SM01405 4 124 3.5E-50 T 23-10-2018 IPR001377 Ribosomal protein S6e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-166208|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_04890 d4067f8e47b771134b89ba0a0c87bc56 361 SUPERFAMILY SSF53448 1 303 1.31E-80 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L08_04890 d4067f8e47b771134b89ba0a0c87bc56 361 Gene3D G3DSA:2.160.10.10 250 361 6.9E-20 T 23-10-2018 A3L08_04890 d4067f8e47b771134b89ba0a0c87bc56 361 SUPERFAMILY SSF51161 200 355 3.19E-26 T 23-10-2018 IPR011004 Trimeric LpxA-like superfamily A3L08_04890 d4067f8e47b771134b89ba0a0c87bc56 361 Pfam PF00483 Nucleotidyl transferase 2 231 1.1E-53 T 23-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 A3L08_04890 d4067f8e47b771134b89ba0a0c87bc56 361 Gene3D G3DSA:3.90.550.10 1 238 8.6E-78 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L08_04890 d4067f8e47b771134b89ba0a0c87bc56 361 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 257 293 4.6E-6 T 23-10-2018 IPR001451 Hexapeptide repeat A3L08_04890 d4067f8e47b771134b89ba0a0c87bc56 361 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 296 329 3.2E-7 T 23-10-2018 IPR001451 Hexapeptide repeat A3L08_07280 d7e7b70b7a2218db66a50b93741620de 965 Gene3D G3DSA:2.40.128.390 614 681 2.8E-82 T 23-10-2018 A3L08_07280 d7e7b70b7a2218db66a50b93741620de 965 Gene3D G3DSA:2.60.40.3020 724 964 1.3E-109 T 23-10-2018 A3L08_07280 d7e7b70b7a2218db66a50b93741620de 965 Gene3D G3DSA:2.60.40.3030 824 956 1.3E-109 T 23-10-2018 A3L08_07280 d7e7b70b7a2218db66a50b93741620de 965 Gene3D G3DSA:3.40.50.12610 508 722 2.8E-82 T 23-10-2018 A3L08_07280 d7e7b70b7a2218db66a50b93741620de 965 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 101 205 6.0E-9 T 23-10-2018 IPR038731 Glycosyltransferase RgtA/B/C/D-like A3L08_07740 2129b7842686401bf2925dfa6ce566e3 1575 Gene3D G3DSA:3.30.565.10 36 211 5.4E-20 T 23-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A3L08_07740 2129b7842686401bf2925dfa6ce566e3 1575 SUPERFAMILY SSF55874 50 196 1.14E-17 T 23-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A3L08_07740 2129b7842686401bf2925dfa6ce566e3 1575 Pfam PF13020 Domain of unknown function (DUF3883) 1464 1549 1.5E-19 T 23-10-2018 IPR024975 Domain of unknown function DUF3883 A3L08_07900 4801b78149b23c1adcebbd3ee8dfb755 244 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 97 193 9.1E-12 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L08_07900 4801b78149b23c1adcebbd3ee8dfb755 244 Gene3D G3DSA:1.10.150.520 16 94 2.0E-86 T 23-10-2018 A3L08_07900 4801b78149b23c1adcebbd3ee8dfb755 244 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 91 195 4.7E-13 T 23-10-2018 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 A3L08_07900 4801b78149b23c1adcebbd3ee8dfb755 244 TIGRFAM TIGR02253 CTE7: HAD hydrolase, TIGR02253 family 1 220 1.7E-86 T 23-10-2018 IPR011950 HAD-superfamily hydrolase, subfamily IA, CTE7 GO:0016787 Reactome: R-HSA-4085001 A3L08_07900 4801b78149b23c1adcebbd3ee8dfb755 244 Gene3D G3DSA:3.40.50.1000 3 220 2.0E-86 T 23-10-2018 IPR023214 HAD superfamily A3L08_07900 4801b78149b23c1adcebbd3ee8dfb755 244 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 108 188 7.7E-14 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L08_07900 4801b78149b23c1adcebbd3ee8dfb755 244 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 106 119 2.4E-9 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L08_07900 4801b78149b23c1adcebbd3ee8dfb755 244 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 2 13 2.4E-9 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L08_07900 4801b78149b23c1adcebbd3ee8dfb755 244 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 137 153 2.4E-9 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L08_07900 4801b78149b23c1adcebbd3ee8dfb755 244 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 155 175 2.4E-9 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L08_07900 4801b78149b23c1adcebbd3ee8dfb755 244 SUPERFAMILY SSF56784 1 225 2.4E-49 T 23-10-2018 IPR036412 HAD-like superfamily A3L08_07900 4801b78149b23c1adcebbd3ee8dfb755 244 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 193 4.1E-32 T 23-10-2018 A3L08_04140 d8486821210de8358c2428fb700e7ab3 148 Gene3D G3DSA:1.10.1650.10 1 54 6.6E-25 T 23-10-2018 IPR015972 Ribosomal protein L19/L19e, domain 1 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_04140 d8486821210de8358c2428fb700e7ab3 148 Pfam PF01280 Ribosomal protein L19e 2 143 2.1E-58 T 23-10-2018 IPR000196 Ribosomal protein L19/L19e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_04140 d8486821210de8358c2428fb700e7ab3 148 Gene3D G3DSA:1.10.1200.240 56 147 5.9E-30 T 23-10-2018 A3L08_04140 d8486821210de8358c2428fb700e7ab3 148 SMART SM01416 1 144 5.8E-88 T 23-10-2018 IPR000196 Ribosomal protein L19/L19e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_04140 d8486821210de8358c2428fb700e7ab3 148 ProSitePatterns PS00526 Ribosomal protein L19e signature. 5 24 - T 23-10-2018 IPR023638 Ribosomal protein L19/L19e conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_04140 d8486821210de8358c2428fb700e7ab3 148 SUPERFAMILY SSF48140 1 141 3.4E-57 T 23-10-2018 IPR035970 Ribosomal protein L19/L19e superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_04140 d8486821210de8358c2428fb700e7ab3 148 Hamap MF_01475 50S ribosomal protein L19e [rpl19e]. 1 147 25.908 T 23-10-2018 IPR000196 Ribosomal protein L19/L19e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_06455 d6c3a71ef23c2e0eba1fec56c6346667 149 SUPERFAMILY SSF53163 2 148 1.7E-31 T 23-10-2018 IPR023430 Peptidase HybD-like domain superfamily A3L08_06455 d6c3a71ef23c2e0eba1fec56c6346667 149 TIGRFAM TIGR00072 hydrog_prot: hydrogenase maturation protease 4 145 6.3E-32 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 A3L08_06455 d6c3a71ef23c2e0eba1fec56c6346667 149 PRINTS PR00446 Hydrogen uptake protein signature 63 79 1.0E-7 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 A3L08_06455 d6c3a71ef23c2e0eba1fec56c6346667 149 PRINTS PR00446 Hydrogen uptake protein signature 3 15 1.0E-7 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 A3L08_06455 d6c3a71ef23c2e0eba1fec56c6346667 149 PRINTS PR00446 Hydrogen uptake protein signature 51 61 1.0E-7 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 A3L08_06455 d6c3a71ef23c2e0eba1fec56c6346667 149 PRINTS PR00446 Hydrogen uptake protein signature 15 26 1.0E-7 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 A3L08_06455 d6c3a71ef23c2e0eba1fec56c6346667 149 Gene3D G3DSA:3.40.50.1450 1 148 7.1E-37 T 23-10-2018 IPR023430 Peptidase HybD-like domain superfamily A3L08_06455 d6c3a71ef23c2e0eba1fec56c6346667 149 Pfam PF01750 Hydrogenase maturation protease 28 144 2.4E-21 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 A3L08_07485 54be8976f415c0be13573785f15e4148 894 Pfam PF09369 Domain of unknown function (DUF1998) 782 864 1.9E-15 T 23-10-2018 IPR018973 DEAD/DEAH-box helicase, putative A3L08_07485 54be8976f415c0be13573785f15e4148 894 Pfam PF00271 Helicase conserved C-terminal domain 267 375 1.8E-19 T 23-10-2018 IPR001650 Helicase, C-terminal A3L08_07485 54be8976f415c0be13573785f15e4148 894 SUPERFAMILY SSF52540 57 378 3.1E-49 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_07485 54be8976f415c0be13573785f15e4148 894 Pfam PF00270 DEAD/DEAH box helicase 50 225 2.5E-22 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A3L08_07485 54be8976f415c0be13573785f15e4148 894 SMART SM00490 292 376 9.4E-19 T 23-10-2018 IPR001650 Helicase, C-terminal A3L08_07485 54be8976f415c0be13573785f15e4148 894 Gene3D G3DSA:3.40.50.300 254 401 6.9E-24 T 23-10-2018 A3L08_07485 54be8976f415c0be13573785f15e4148 894 Gene3D G3DSA:3.40.50.300 32 242 1.4E-40 T 23-10-2018 A3L08_07485 54be8976f415c0be13573785f15e4148 894 SMART SM00487 44 253 2.9E-27 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A3L08_06295 22212b95093fcb454b16edcae77b7670 415 SUPERFAMILY SSF53137 138 271 1.26E-43 T 23-10-2018 A3L08_06295 22212b95093fcb454b16edcae77b7670 415 Gene3D G3DSA:3.30.1330.30 274 415 9.7E-44 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like A3L08_06295 22212b95093fcb454b16edcae77b7670 415 Pfam PF03463 eRF1 domain 1 17 133 3.2E-9 T 23-10-2018 IPR005140 eRF1 domain 1/Pelota-like A3L08_06295 22212b95093fcb454b16edcae77b7670 415 SMART SM01194 1 135 1.5E-33 T 23-10-2018 IPR005140 eRF1 domain 1/Pelota-like A3L08_06295 22212b95093fcb454b16edcae77b7670 415 TIGRFAM TIGR03676 aRF1/eRF1: peptide chain release factor 1, archaeal and eukaryotic forms 7 414 1.7E-181 T 23-10-2018 IPR004403 Peptide chain release factor eRF1/aRF1 GO:0003747|GO:0005737|GO:0006415 Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_06295 22212b95093fcb454b16edcae77b7670 415 SUPERFAMILY SSF55315 272 414 9.42E-41 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like A3L08_06295 22212b95093fcb454b16edcae77b7670 415 Gene3D G3DSA:3.30.420.60 131 271 1.9E-54 T 23-10-2018 A3L08_06295 22212b95093fcb454b16edcae77b7670 415 SUPERFAMILY SSF55481 3 135 1.57E-48 T 23-10-2018 IPR024049 Peptide Chain Release Factor eRF1/aRF1, N-terminal Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_06295 22212b95093fcb454b16edcae77b7670 415 Pfam PF03465 eRF1 domain 3 276 414 1.2E-34 T 23-10-2018 IPR005142 eRF1 domain 3 A3L08_06295 22212b95093fcb454b16edcae77b7670 415 Gene3D G3DSA:3.30.960.10 1 130 1.8E-54 T 23-10-2018 IPR024049 Peptide Chain Release Factor eRF1/aRF1, N-terminal Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_06295 22212b95093fcb454b16edcae77b7670 415 Hamap MF_00424 Peptide chain release factor subunit 1 [prf1]. 18 415 45.328 T 23-10-2018 IPR020918 Peptide chain release factor aRF1 GO:0003747|GO:0005737|GO:0006415 A3L08_06295 22212b95093fcb454b16edcae77b7670 415 Pfam PF03464 eRF1 domain 2 140 272 1.7E-49 T 23-10-2018 IPR005141 eRF1 domain 2 A3L08_02475 9da111ba4715fa15c350d97b1b5212a6 517 Pfam PF12679 ABC-2 family transporter protein 304 516 1.1E-17 T 23-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 A3L08_08860 20e0279e3a58b818cb1d7239460ceaf3 379 Gene3D G3DSA:3.40.190.10 30 306 2.6E-117 T 23-10-2018 A3L08_08860 20e0279e3a58b818cb1d7239460ceaf3 379 TIGRFAM TIGR01254 sfuA: ABC transporter periplasmic binding protein, thiB subfamily 25 330 5.9E-100 T 23-10-2018 IPR005948 Thiamine/thiamin pyrophosphate-binding periplasmic protein, ABC transporter GO:0015888|GO:0030975 A3L08_08860 20e0279e3a58b818cb1d7239460ceaf3 379 Pfam PF13343 Bacterial extracellular solute-binding protein 77 321 1.6E-32 T 23-10-2018 A3L08_08860 20e0279e3a58b818cb1d7239460ceaf3 379 TIGRFAM TIGR04288 CGP_CTERM: CGP-CTERM domain 359 378 3.5E-8 T 23-10-2018 IPR027552 CGP-CTERM domain A3L08_08860 20e0279e3a58b818cb1d7239460ceaf3 379 Gene3D G3DSA:3.40.190.10 131 331 2.6E-117 T 23-10-2018 A3L08_08860 20e0279e3a58b818cb1d7239460ceaf3 379 SUPERFAMILY SSF53850 25 331 1.2E-81 T 23-10-2018 A3L08_08860 20e0279e3a58b818cb1d7239460ceaf3 379 PIRSF PIRSF002825 15 335 1.4E-50 T 23-10-2018 IPR026045 Ferric binding protein A3L08_05535 6c52c3f5ab040a0d07dd816bd295938e 112 Gene3D G3DSA:1.20.120.580 43 110 2.9E-5 T 23-10-2018 IPR037038 Bsu32300-like superfamily A3L08_05535 6c52c3f5ab040a0d07dd816bd295938e 112 Pfam PF01934 Protein of unknown function DUF86 5 105 8.9E-9 T 23-10-2018 IPR008201 Protein of unknown function DUF86 A3L08_04420 08e8c154674b6b80c85045efab2ff196 444 SUPERFAMILY SSF56281 2 443 1.9E-63 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L08_04420 08e8c154674b6b80c85045efab2ff196 444 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 375 425 2.5E-13 T 23-10-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain A3L08_04420 08e8c154674b6b80c85045efab2ff196 444 SMART SM00849 14 225 4.0E-20 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L08_04420 08e8c154674b6b80c85045efab2ff196 444 TIGRFAM TIGR00649 MG423: beta-CASP ribonuclease, RNase J family 2 443 8.8E-157 T 23-10-2018 IPR004613 Ribonuclease J GO:0003723|GO:0046872 A3L08_04420 08e8c154674b6b80c85045efab2ff196 444 ProSitePatterns PS01292 Uncharacterized protein family UPF0036 signature. 382 410 - T 23-10-2018 IPR001587 Ribonuclease J, conserved site A3L08_04420 08e8c154674b6b80c85045efab2ff196 444 Hamap MF_01492 Ribonuclease J [rnj]. 1 444 48.687 T 23-10-2018 IPR030879 Ribonuclease J, archaea GO:0003723|GO:0004534|GO:0090503 A3L08_04420 08e8c154674b6b80c85045efab2ff196 444 Gene3D G3DSA:3.60.15.10 3 443 1.9E-134 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L08_04420 08e8c154674b6b80c85045efab2ff196 444 Gene3D G3DSA:3.40.50.10710 219 378 1.9E-134 T 23-10-2018 A3L08_04420 08e8c154674b6b80c85045efab2ff196 444 Pfam PF00753 Metallo-beta-lactamase superfamily 16 187 9.3E-13 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L08_09435 543644b147ac8ef43f6a6c75d594995b 235 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 1 196 6.9E-31 T 23-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 A3L08_09435 543644b147ac8ef43f6a6c75d594995b 235 Gene3D G3DSA:3.60.21.10 2 235 9.3E-73 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like A3L08_09435 543644b147ac8ef43f6a6c75d594995b 235 SUPERFAMILY SSF56300 1 235 1.22E-66 T 23-10-2018 A3L08_09435 543644b147ac8ef43f6a6c75d594995b 235 PIRSF PIRSF000883 1 235 4.5E-74 T 23-10-2018 IPR011152 Phosphoesterase MJ0912 A3L08_05555 3dabd112e663394cac346d403c8ed40a 174 SUPERFAMILY SSF51161 5 169 7.49E-50 T 23-10-2018 IPR011004 Trimeric LpxA-like superfamily A3L08_05555 3dabd112e663394cac346d403c8ed40a 174 Gene3D G3DSA:2.160.10.10 1 173 4.7E-63 T 23-10-2018 A3L08_05555 3dabd112e663394cac346d403c8ed40a 174 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 89 121 1.5E-7 T 23-10-2018 IPR001451 Hexapeptide repeat A3L08_06440 51ba2228a5e1ead3ce19daa2184b159e 634 Pfam PF01078 Magnesium chelatase, subunit ChlI 40 92 1.6E-9 T 23-10-2018 IPR000523 Magnesium chelatase ChlI domain A3L08_06440 51ba2228a5e1ead3ce19daa2184b159e 634 TIGRFAM TIGR00764 lon_rel: putative ATP-dependent protease 23 628 0.0 T 23-10-2018 IPR004663 Lon protease, archaeal GO:0004176|GO:0005524|GO:0030163 A3L08_06440 51ba2228a5e1ead3ce19daa2184b159e 634 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 433 614 5.3E-36 T 23-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 A3L08_06440 51ba2228a5e1ead3ce19daa2184b159e 634 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 439 455 8.0E-29 T 23-10-2018 A3L08_06440 51ba2228a5e1ead3ce19daa2184b159e 634 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 569 587 8.0E-29 T 23-10-2018 A3L08_06440 51ba2228a5e1ead3ce19daa2184b159e 634 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 516 535 8.0E-29 T 23-10-2018 A3L08_06440 51ba2228a5e1ead3ce19daa2184b159e 634 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 546 565 8.0E-29 T 23-10-2018 A3L08_06440 51ba2228a5e1ead3ce19daa2184b159e 634 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 66 85 8.0E-29 T 23-10-2018 A3L08_06440 51ba2228a5e1ead3ce19daa2184b159e 634 Gene3D G3DSA:3.30.230.10 431 634 1.8E-79 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A3L08_06440 51ba2228a5e1ead3ce19daa2184b159e 634 SMART SM00382 58 317 2.2E-5 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L08_06440 51ba2228a5e1ead3ce19daa2184b159e 634 Pfam PF13654 AAA domain 182 410 9.1E-23 T 23-10-2018 A3L08_06440 51ba2228a5e1ead3ce19daa2184b159e 634 Gene3D G3DSA:1.10.8.60 320 412 9.1E-44 T 23-10-2018 A3L08_06440 51ba2228a5e1ead3ce19daa2184b159e 634 Gene3D G3DSA:3.40.50.300 161 319 8.7E-43 T 23-10-2018 A3L08_06440 51ba2228a5e1ead3ce19daa2184b159e 634 Gene3D G3DSA:3.40.50.300 19 130 2.3E-31 T 23-10-2018 A3L08_06440 51ba2228a5e1ead3ce19daa2184b159e 634 SUPERFAMILY SSF54211 439 612 2.88E-43 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A3L08_06440 51ba2228a5e1ead3ce19daa2184b159e 634 SUPERFAMILY SSF52540 35 413 1.73E-37 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_07725 cd54ba10980ffbd548f4cbc52cf98a9a 441 Pfam PF01523 Putative modulator of DNA gyrase 15 304 2.4E-44 T 23-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 A3L08_07725 cd54ba10980ffbd548f4cbc52cf98a9a 441 Gene3D G3DSA:3.30.2290.10 1 206 1.4E-18 T 23-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal A3L08_07725 cd54ba10980ffbd548f4cbc52cf98a9a 441 SUPERFAMILY SSF111283 3 439 4.97E-94 T 23-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 A3L08_09500 e014be23a0fd5f48267591b67d401520 90 Hamap MF_00410 50S ribosomal protein L31e [rpl31e]. 4 90 22.127 T 23-10-2018 IPR000054 Ribosomal protein L31e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_09500 e014be23a0fd5f48267591b67d401520 90 ProSitePatterns PS01144 Ribosomal protein L31e signature. 48 62 - T 23-10-2018 IPR020052 Ribosomal protein L31e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_09500 e014be23a0fd5f48267591b67d401520 90 SUPERFAMILY SSF54575 7 84 1.83E-22 T 23-10-2018 IPR023621 Ribosomal protein L31e domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_09500 e014be23a0fd5f48267591b67d401520 90 ProDom PD006030 RIBOSOMAL 60S L31 RIBONUCLEOPROTEIN L31E 50S L31 SUBUNIT STRAIN PHOSPHORYLATION 13 58 7.0E-18 T 23-10-2018 IPR000054 Ribosomal protein L31e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_09500 e014be23a0fd5f48267591b67d401520 90 SMART SM01380 8 85 2.1E-20 T 23-10-2018 IPR000054 Ribosomal protein L31e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_09500 e014be23a0fd5f48267591b67d401520 90 Gene3D G3DSA:3.10.440.10 2 90 4.4E-26 T 23-10-2018 IPR023621 Ribosomal protein L31e domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_09500 e014be23a0fd5f48267591b67d401520 90 Pfam PF01198 Ribosomal protein L31e 13 80 1.3E-9 T 23-10-2018 IPR000054 Ribosomal protein L31e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_05795 7c34472324025702f5880b5243f53022 572 SMART SM00116 451 499 7.5E-7 T 23-10-2018 IPR000644 CBS domain A3L08_05795 7c34472324025702f5880b5243f53022 572 SMART SM00116 512 563 0.14 T 23-10-2018 IPR000644 CBS domain A3L08_05795 7c34472324025702f5880b5243f53022 572 Pfam PF00654 Voltage gated chloride channel 69 411 2.3E-89 T 23-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 A3L08_05795 7c34472324025702f5880b5243f53022 572 Pfam PF00571 CBS domain 444 497 4.0E-12 T 23-10-2018 IPR000644 CBS domain A3L08_05795 7c34472324025702f5880b5243f53022 572 Pfam PF00571 CBS domain 518 561 3.7E-6 T 23-10-2018 IPR000644 CBS domain A3L08_05795 7c34472324025702f5880b5243f53022 572 Gene3D G3DSA:1.10.3080.10 2 432 1.7E-98 T 23-10-2018 IPR014743 Chloride channel, core Reactome: R-HSA-2672351 A3L08_05795 7c34472324025702f5880b5243f53022 572 SUPERFAMILY SSF81340 4 431 8.89E-102 T 23-10-2018 IPR014743 Chloride channel, core Reactome: R-HSA-2672351 A3L08_05795 7c34472324025702f5880b5243f53022 572 Gene3D G3DSA:3.10.580.10 437 564 5.4E-23 T 23-10-2018 A3L08_05795 7c34472324025702f5880b5243f53022 572 PRINTS PR00762 Chloride channel signature 81 98 2.4E-17 T 23-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 A3L08_05795 7c34472324025702f5880b5243f53022 572 PRINTS PR00762 Chloride channel signature 326 346 2.4E-17 T 23-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 A3L08_05795 7c34472324025702f5880b5243f53022 572 PRINTS PR00762 Chloride channel signature 161 180 2.4E-17 T 23-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 A3L08_05795 7c34472324025702f5880b5243f53022 572 PRINTS PR00762 Chloride channel signature 361 377 2.4E-17 T 23-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 A3L08_05795 7c34472324025702f5880b5243f53022 572 SUPERFAMILY SSF54631 437 563 7.67E-26 T 23-10-2018 A3L08_05850 31d824e9a546897d5d4046aeb4ce1041 309 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 117 127 7.0E-30 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L08_05850 31d824e9a546897d5d4046aeb4ce1041 309 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 183 195 7.0E-30 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L08_05850 31d824e9a546897d5d4046aeb4ce1041 309 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 291 308 7.0E-30 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L08_05850 31d824e9a546897d5d4046aeb4ce1041 309 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 233 249 7.0E-30 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L08_05850 31d824e9a546897d5d4046aeb4ce1041 309 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 88 102 7.0E-30 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L08_05850 31d824e9a546897d5d4046aeb4ce1041 309 SUPERFAMILY SSF53335 8 308 8.9E-78 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L08_05850 31d824e9a546897d5d4046aeb4ce1041 309 Gene3D G3DSA:3.30.70.3130 1 101 6.9E-36 T 23-10-2018 A3L08_05850 31d824e9a546897d5d4046aeb4ce1041 309 ProSitePatterns PS01153 NOL1/NOP2/sun family signature. 182 193 - T 23-10-2018 IPR018314 Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site GO:0003723|GO:0008168 A3L08_05850 31d824e9a546897d5d4046aeb4ce1041 309 Pfam PF17125 N-terminal domain of 16S rRNA methyltransferase RsmF 12 102 3.6E-20 T 23-10-2018 IPR031341 Ribosomal RNA small subunit methyltransferase F, N-terminal Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 A3L08_05850 31d824e9a546897d5d4046aeb4ce1041 309 Pfam PF01189 16S rRNA methyltransferase RsmB/F 106 307 2.7E-58 T 23-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 A3L08_05850 31d824e9a546897d5d4046aeb4ce1041 309 Gene3D G3DSA:3.40.50.150 103 309 1.4E-69 T 23-10-2018 A3L08_05850 31d824e9a546897d5d4046aeb4ce1041 309 TIGRFAM TIGR00446 nop2p: NOL1/NOP2/sun family putative RNA methylase 42 308 4.3E-89 T 23-10-2018 IPR011023 Nop2p GO:0003723|GO:0006364|GO:0008757 Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 A3L08_08745 5a36e1000dd86b5a2394f3e21ff97969 556 Gene3D G3DSA:3.40.50.300 308 528 2.5E-56 T 23-10-2018 A3L08_08745 5a36e1000dd86b5a2394f3e21ff97969 556 Gene3D G3DSA:3.40.50.300 126 269 3.2E-22 T 23-10-2018 A3L08_08745 5a36e1000dd86b5a2394f3e21ff97969 556 Pfam PF01935 Domain of unknown function DUF87 139 369 1.9E-43 T 23-10-2018 IPR002789 Helicase HerA, central domain A3L08_08745 5a36e1000dd86b5a2394f3e21ff97969 556 Pfam PF05872 Bacterial protein of unknown function (DUF853) 401 501 4.4E-5 T 23-10-2018 IPR033186 Helicase HerA-like C-terminal A3L08_08745 5a36e1000dd86b5a2394f3e21ff97969 556 Pfam PF09378 HAS barrel domain 7 99 4.0E-8 T 23-10-2018 IPR018538 Helicase HerA, barrel domain A3L08_08745 5a36e1000dd86b5a2394f3e21ff97969 556 SUPERFAMILY SSF52540 131 520 3.34E-40 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_09375 80e53cdc383e8650848d18e2f91a85f1 480 Gene3D G3DSA:3.60.20.10 2 215 1.9E-42 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A3L08_09375 80e53cdc383e8650848d18e2f91a85f1 480 Pfam PF00733 Asparagine synthase 230 360 2.2E-34 T 23-10-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 A3L08_09375 80e53cdc383e8650848d18e2f91a85f1 480 Pfam PF00733 Asparagine synthase 364 456 1.5E-18 T 23-10-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 A3L08_09375 80e53cdc383e8650848d18e2f91a85f1 480 Gene3D G3DSA:3.40.50.620 216 479 1.4E-72 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L08_09375 80e53cdc383e8650848d18e2f91a85f1 480 SUPERFAMILY SSF56235 11 206 1.37E-42 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A3L08_09375 80e53cdc383e8650848d18e2f91a85f1 480 SUPERFAMILY SSF52402 217 477 1.01E-57 T 23-10-2018 A3L08_09375 80e53cdc383e8650848d18e2f91a85f1 480 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 363 3.9E-84 T 23-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 A3L08_09375 80e53cdc383e8650848d18e2f91a85f1 480 Pfam PF13537 Glutamine amidotransferase domain 61 179 6.0E-26 T 23-10-2018 IPR017932 Glutamine amidotransferase type 2 domain A3L08_09375 80e53cdc383e8650848d18e2f91a85f1 480 PIRSF PIRSF001589 365 480 1.1E-14 T 23-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 A3L08_09375 80e53cdc383e8650848d18e2f91a85f1 480 PIRSF PIRSF001589 1 378 4.0E-61 T 23-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 A3L08_02895 9ccf3c516e9cf20c4dfdf7d3254981f3 173 SUPERFAMILY SSF54862 1 139 9.21E-35 T 23-10-2018 A3L08_02895 9ccf3c516e9cf20c4dfdf7d3254981f3 173 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 89 100 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L08_02895 9ccf3c516e9cf20c4dfdf7d3254981f3 173 Gene3D G3DSA:3.30.70.20 62 115 8.4E-20 T 23-10-2018 A3L08_02895 9ccf3c516e9cf20c4dfdf7d3254981f3 173 Gene3D G3DSA:3.30.70.20 10 132 8.4E-20 T 23-10-2018 A3L08_02895 9ccf3c516e9cf20c4dfdf7d3254981f3 173 Pfam PF13247 4Fe-4S dicluster domain 52 130 5.4E-11 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L08_02895 9ccf3c516e9cf20c4dfdf7d3254981f3 173 Pfam PF12800 4Fe-4S binding domain 13 27 0.026 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L08_05350 ebcb0c3ffb100107175602617e253afd 772 Pfam PF01300 Telomere recombination 208 383 9.0E-46 T 23-10-2018 IPR006070 YrdC-like domain GO:0003725 A3L08_05350 ebcb0c3ffb100107175602617e253afd 772 TIGRFAM TIGR00143 hypF: carbamoyltransferase HypF 6 755 3.7E-262 T 23-10-2018 IPR004421 Carbamoyltransferase, HypF-type GO:0016743|GO:0046872|GO:0046944 A3L08_05350 ebcb0c3ffb100107175602617e253afd 772 Pfam PF00814 Glycoprotease family 609 740 2.9E-7 T 23-10-2018 IPR000905 Gcp-like domain A3L08_05350 ebcb0c3ffb100107175602617e253afd 772 Gene3D G3DSA:3.30.110.120 252 371 1.2E-144 T 23-10-2018 A3L08_05350 ebcb0c3ffb100107175602617e253afd 772 Gene3D G3DSA:3.90.870.50 6 362 1.2E-144 T 23-10-2018 A3L08_05350 ebcb0c3ffb100107175602617e253afd 772 Gene3D G3DSA:3.30.420.360 383 755 8.6E-104 T 23-10-2018 A3L08_05350 ebcb0c3ffb100107175602617e253afd 772 Gene3D G3DSA:3.30.420.350 486 743 8.6E-104 T 23-10-2018 A3L08_05350 ebcb0c3ffb100107175602617e253afd 772 SUPERFAMILY SSF55821 175 390 2.53E-44 T 23-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily A3L08_05350 ebcb0c3ffb100107175602617e253afd 772 SUPERFAMILY SSF53067 400 736 2.12E-8 T 23-10-2018 A3L08_05350 ebcb0c3ffb100107175602617e253afd 772 Pfam PF07503 HypF finger 158 191 2.2E-15 T 23-10-2018 IPR011125 Zinc finger, HypF-type GO:0008270 A3L08_05350 ebcb0c3ffb100107175602617e253afd 772 Pfam PF07503 HypF finger 108 141 1.5E-16 T 23-10-2018 IPR011125 Zinc finger, HypF-type GO:0008270 A3L08_05350 ebcb0c3ffb100107175602617e253afd 772 PIRSF PIRSF006256 1 765 8.5E-283 T 23-10-2018 IPR004421 Carbamoyltransferase, HypF-type GO:0016743|GO:0046872|GO:0046944 A3L08_05350 ebcb0c3ffb100107175602617e253afd 772 SUPERFAMILY SSF54975 1 88 2.07E-27 T 23-10-2018 IPR036046 Acylphosphatase-like domain superfamily KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 A3L08_05350 ebcb0c3ffb100107175602617e253afd 772 Pfam PF00708 Acylphosphatase 4 86 8.8E-25 T 23-10-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 A3L08_08190 3d2731515f253839c153201f9c63e4fb 450 Gene3D G3DSA:3.40.190.10 51 407 9.6E-114 T 23-10-2018 A3L08_08190 3d2731515f253839c153201f9c63e4fb 450 ProSitePatterns PS01037 Bacterial extracellular solute-binding proteins, family 1 signature. 160 177 - T 23-10-2018 IPR006061 Solute-binding family 1, conserved site GO:0055085 A3L08_08190 3d2731515f253839c153201f9c63e4fb 450 Gene3D G3DSA:3.40.190.10 165 442 9.6E-114 T 23-10-2018 A3L08_08190 3d2731515f253839c153201f9c63e4fb 450 Pfam PF13416 Bacterial extracellular solute-binding protein 67 385 2.6E-52 T 23-10-2018 IPR006059 Bacterial extracellular solute-binding protein A3L08_08190 3d2731515f253839c153201f9c63e4fb 450 SUPERFAMILY SSF53850 48 445 2.87E-98 T 23-10-2018 A3L08_06980 f25947ea9fdc56e787346e57a2e0c98e 502 PRINTS PR00131 Glycosyl hydrolase family 1 signature 456 468 1.1E-16 T 23-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A3L08_06980 f25947ea9fdc56e787346e57a2e0c98e 502 PRINTS PR00131 Glycosyl hydrolase family 1 signature 411 422 1.1E-16 T 23-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A3L08_06980 f25947ea9fdc56e787346e57a2e0c98e 502 PRINTS PR00131 Glycosyl hydrolase family 1 signature 322 336 1.1E-16 T 23-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A3L08_06980 f25947ea9fdc56e787346e57a2e0c98e 502 PRINTS PR00131 Glycosyl hydrolase family 1 signature 399 407 1.1E-16 T 23-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A3L08_06980 f25947ea9fdc56e787346e57a2e0c98e 502 PRINTS PR00131 Glycosyl hydrolase family 1 signature 432 449 1.1E-16 T 23-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A3L08_06980 f25947ea9fdc56e787346e57a2e0c98e 502 SUPERFAMILY SSF51445 3 491 1.37E-123 T 23-10-2018 IPR017853 Glycoside hydrolase superfamily A3L08_06980 f25947ea9fdc56e787346e57a2e0c98e 502 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 5 19 - T 23-10-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site A3L08_06980 f25947ea9fdc56e787346e57a2e0c98e 502 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 399 407 - T 23-10-2018 IPR018120 Glycoside hydrolase family 1, active site A3L08_06980 f25947ea9fdc56e787346e57a2e0c98e 502 Pfam PF00232 Glycosyl hydrolase family 1 124 486 5.3E-57 T 23-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A3L08_06980 f25947ea9fdc56e787346e57a2e0c98e 502 Pfam PF00232 Glycosyl hydrolase family 1 2 91 1.1E-8 T 23-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A3L08_06980 f25947ea9fdc56e787346e57a2e0c98e 502 Gene3D G3DSA:3.20.20.80 1 498 1.1E-139 T 23-10-2018 A3L08_08320 13370e9d0b1c94aef71b4d177e239a57 270 Pfam PF00924 Mechanosensitive ion channel 60 256 4.8E-50 T 23-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 A3L08_08320 13370e9d0b1c94aef71b4d177e239a57 270 Gene3D G3DSA:2.30.30.60 117 166 3.1E-15 T 23-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily A3L08_08320 13370e9d0b1c94aef71b4d177e239a57 270 SUPERFAMILY SSF82689 168 266 1.03E-35 T 23-10-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 A3L08_08320 13370e9d0b1c94aef71b4d177e239a57 270 SUPERFAMILY SSF82861 16 100 3.79E-10 T 23-10-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 A3L08_08320 13370e9d0b1c94aef71b4d177e239a57 270 SUPERFAMILY SSF50182 101 167 3.27E-15 T 23-10-2018 IPR010920 LSM domain superfamily A3L08_08320 13370e9d0b1c94aef71b4d177e239a57 270 Gene3D G3DSA:3.30.70.100 167 261 1.7E-32 T 23-10-2018 A3L08_00140 c229ecab6ac13a5f8b4a442599632da5 382 SUPERFAMILY SSF51735 1 379 2.05E-75 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L08_00140 c229ecab6ac13a5f8b4a442599632da5 382 Gene3D G3DSA:3.30.360.10 216 319 5.9E-139 T 23-10-2018 A3L08_00140 c229ecab6ac13a5f8b4a442599632da5 382 Pfam PF01658 Myo-inositol-1-phosphate synthase 212 317 4.6E-20 T 23-10-2018 IPR013021 Myo-inositol-1-phosphate synthase, GAPDH-like KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 A3L08_00140 c229ecab6ac13a5f8b4a442599632da5 382 PIRSF PIRSF015578 1 379 1.1E-97 T 23-10-2018 IPR002587 Myo-inositol-1-phosphate synthase GO:0004512|GO:0006021|GO:0008654 KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 A3L08_00140 c229ecab6ac13a5f8b4a442599632da5 382 Pfam PF07994 Myo-inositol-1-phosphate synthase 121 211 1.0E-9 T 23-10-2018 IPR002587 Myo-inositol-1-phosphate synthase GO:0004512|GO:0006021|GO:0008654 KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 A3L08_00140 c229ecab6ac13a5f8b4a442599632da5 382 Gene3D G3DSA:3.40.50.720 3 354 5.9E-139 T 23-10-2018 A3L08_00140 c229ecab6ac13a5f8b4a442599632da5 382 SUPERFAMILY SSF55347 211 316 1.57E-28 T 23-10-2018 A3L08_03700 fadcf40e23aa385482ffdf1ac413dafe 205 Pfam PF01871 AMMECR1 13 190 4.8E-54 T 23-10-2018 IPR002733 AMMECR1 domain A3L08_03700 fadcf40e23aa385482ffdf1ac413dafe 205 SUPERFAMILY SSF143447 4 202 3.01E-70 T 23-10-2018 IPR036071 AMMECR1 domain superfamily A3L08_03700 fadcf40e23aa385482ffdf1ac413dafe 205 TIGRFAM TIGR04335 AmmeMemoSam_A: AmmeMemoRadiSam system protein A 11 190 8.0E-59 T 23-10-2018 IPR027623 AmmeMemoRadiSam system protein A A3L08_03700 fadcf40e23aa385482ffdf1ac413dafe 205 Hamap MF_00645 Protein . 5 188 42.032 T 23-10-2018 IPR023472 Uncharacterised protein family MJ0810 A3L08_03700 fadcf40e23aa385482ffdf1ac413dafe 205 Gene3D G3DSA:3.30.700.20 6 197 7.9E-74 T 23-10-2018 IPR027485 AMMECR1, N-terminal A3L08_03700 fadcf40e23aa385482ffdf1ac413dafe 205 Gene3D G3DSA:3.30.1490.150 113 186 7.9E-74 T 23-10-2018 A3L08_03700 fadcf40e23aa385482ffdf1ac413dafe 205 TIGRFAM TIGR00296 TIGR00296: uncharacterized protein, PH0010 family 4 197 1.5E-68 T 23-10-2018 IPR023473 AMMECR1 A3L08_09010 1a95bc45809e3f02816667466b520bb6 412 Gene3D G3DSA:3.40.50.1260 8 397 2.0E-139 T 23-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L08_09010 1a95bc45809e3f02816667466b520bb6 412 ProSitePatterns PS00111 Phosphoglycerate kinase signature. 13 23 - T 23-10-2018 IPR015911 Phosphoglycerate kinase, conserved site GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L08_09010 1a95bc45809e3f02816667466b520bb6 412 PIRSF PIRSF000724 1 407 2.8E-130 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L08_09010 1a95bc45809e3f02816667466b520bb6 412 SUPERFAMILY SSF53748 2 398 4.0E-116 T 23-10-2018 IPR036043 Phosphoglycerate kinase superfamily GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L08_09010 1a95bc45809e3f02816667466b520bb6 412 PRINTS PR00477 Phosphoglycerate kinase family signature 354 365 6.1E-66 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L08_09010 1a95bc45809e3f02816667466b520bb6 412 PRINTS PR00477 Phosphoglycerate kinase family signature 105 120 6.1E-66 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L08_09010 1a95bc45809e3f02816667466b520bb6 412 PRINTS PR00477 Phosphoglycerate kinase family signature 170 192 6.1E-66 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L08_09010 1a95bc45809e3f02816667466b520bb6 412 PRINTS PR00477 Phosphoglycerate kinase family signature 140 162 6.1E-66 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L08_09010 1a95bc45809e3f02816667466b520bb6 412 PRINTS PR00477 Phosphoglycerate kinase family signature 8 24 6.1E-66 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L08_09010 1a95bc45809e3f02816667466b520bb6 412 PRINTS PR00477 Phosphoglycerate kinase family signature 193 212 6.1E-66 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L08_09010 1a95bc45809e3f02816667466b520bb6 412 PRINTS PR00477 Phosphoglycerate kinase family signature 321 346 6.1E-66 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L08_09010 1a95bc45809e3f02816667466b520bb6 412 PRINTS PR00477 Phosphoglycerate kinase family signature 376 393 6.1E-66 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L08_09010 1a95bc45809e3f02816667466b520bb6 412 PRINTS PR00477 Phosphoglycerate kinase family signature 29 51 6.1E-66 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L08_09010 1a95bc45809e3f02816667466b520bb6 412 Gene3D G3DSA:3.40.50.1260 189 390 2.0E-139 T 23-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L08_09010 1a95bc45809e3f02816667466b520bb6 412 Pfam PF00162 Phosphoglycerate kinase 5 389 1.0E-106 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L08_09010 1a95bc45809e3f02816667466b520bb6 412 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 4 400 34.547 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L08_08470 41fbcb9d74482525d8988af732471efc 147 TIGRFAM TIGR00293 TIGR00293: prefoldin, alpha subunit 8 138 4.1E-37 T 23-10-2018 IPR011599 Prefoldin alpha subunit, archaea-type GO:0006457|GO:0016272|GO:0051082 Reactome: R-HSA-389957 A3L08_08470 41fbcb9d74482525d8988af732471efc 147 SUPERFAMILY SSF46579 7 139 9.68E-31 T 23-10-2018 A3L08_08470 41fbcb9d74482525d8988af732471efc 147 Pfam PF02996 Prefoldin subunit 18 137 1.7E-27 T 23-10-2018 IPR004127 Prefoldin alpha-like A3L08_08470 41fbcb9d74482525d8988af732471efc 147 Gene3D G3DSA:1.10.287.370 1 146 8.9E-47 T 23-10-2018 IPR009053 Prefoldin A3L08_08470 41fbcb9d74482525d8988af732471efc 147 Hamap MF_00308 Prefoldin subunit alpha [pfdA]. 3 138 15.796 T 23-10-2018 IPR011599 Prefoldin alpha subunit, archaea-type GO:0006457|GO:0016272|GO:0051082 Reactome: R-HSA-389957 A3L08_00470 2800844ffa2bbed1a834c95fbe0e3e26 202 SUPERFAMILY SSF53323 4 199 6.93E-45 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 A3L08_00470 2800844ffa2bbed1a834c95fbe0e3e26 202 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 12 194 1.5E-40 T 23-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 A3L08_00470 2800844ffa2bbed1a834c95fbe0e3e26 202 TIGRFAM TIGR03334 IOR_beta: indolepyruvate ferredoxin oxidoreductase, beta subunit 4 193 8.9E-88 T 23-10-2018 IPR017719 Indolepyruvate ferredoxin oxidoreductase, beta subunit GO:0043805|GO:0055114 A3L08_00470 2800844ffa2bbed1a834c95fbe0e3e26 202 Gene3D G3DSA:3.40.920.10 1 200 6.7E-50 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 A3L08_08755 1ddcfa1ba7dd3cbb59c7b1cdc00ea41c 887 Hamap MF_00449 DNA double-strand break repair Rad50 ATPase [rad50]. 1 881 12.419 T 23-10-2018 IPR022982 DNA double-strand break repair Rad50 ATPase, archaeal type A3L08_08755 1ddcfa1ba7dd3cbb59c7b1cdc00ea41c 887 Gene3D G3DSA:3.40.50.300 2 232 2.5E-35 T 23-10-2018 A3L08_08755 1ddcfa1ba7dd3cbb59c7b1cdc00ea41c 887 Gene3D G3DSA:3.40.50.300 670 883 3.1E-36 T 23-10-2018 A3L08_08755 1ddcfa1ba7dd3cbb59c7b1cdc00ea41c 887 SUPERFAMILY SSF52540 2 871 1.35E-25 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_08755 1ddcfa1ba7dd3cbb59c7b1cdc00ea41c 887 Gene3D G3DSA:1.10.287.510 385 500 3.6E-9 T 23-10-2018 A3L08_08755 1ddcfa1ba7dd3cbb59c7b1cdc00ea41c 887 Pfam PF04423 Rad50 zinc hook motif 425 468 9.2E-8 T 23-10-2018 IPR013134 RAD50, zinc hook Reactome: R-HSA-2559586|Reactome: R-HSA-5685938|Reactome: R-HSA-5685939|Reactome: R-HSA-5685942|Reactome: R-HSA-5693548|Reactome: R-HSA-5693554|Reactome: R-HSA-5693565|Reactome: R-HSA-5693568|Reactome: R-HSA-5693571|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 A3L08_08755 1ddcfa1ba7dd3cbb59c7b1cdc00ea41c 887 SUPERFAMILY SSF52540 492 879 3.1E-16 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_08755 1ddcfa1ba7dd3cbb59c7b1cdc00ea41c 887 Pfam PF13555 P-loop containing region of AAA domain 4 48 8.0E-7 T 23-10-2018 A3L08_08755 1ddcfa1ba7dd3cbb59c7b1cdc00ea41c 887 SUPERFAMILY SSF75712 392 488 1.15E-10 T 23-10-2018 A3L08_08755 1ddcfa1ba7dd3cbb59c7b1cdc00ea41c 887 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 614 860 1.5E-6 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A3L08_08755 1ddcfa1ba7dd3cbb59c7b1cdc00ea41c 887 SMART SM00382 22 874 0.003 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L08_08245 679a6a6759b3085ee16569d4b4d94b19 53 PRINTS PR00163 Rubredoxin signature 3 19 4.0E-12 T 23-10-2018 IPR024935 Rubredoxin domain GO:0005506 A3L08_08245 679a6a6759b3085ee16569d4b4d94b19 53 PRINTS PR00163 Rubredoxin signature 33 49 4.0E-12 T 23-10-2018 IPR024935 Rubredoxin domain GO:0005506 A3L08_08245 679a6a6759b3085ee16569d4b4d94b19 53 PIRSF PIRSF000071 1 53 4.7E-29 T 23-10-2018 IPR024922 Rubredoxin GO:0005506|GO:0009055 A3L08_08245 679a6a6759b3085ee16569d4b4d94b19 53 ProSitePatterns PS00202 Rubredoxin signature. 33 43 - T 23-10-2018 IPR018527 Rubredoxin, iron-binding site GO:0046872 A3L08_08245 679a6a6759b3085ee16569d4b4d94b19 53 SUPERFAMILY SSF57802 1 53 5.05E-25 T 23-10-2018 A3L08_08245 679a6a6759b3085ee16569d4b4d94b19 53 Gene3D G3DSA:2.20.28.10 2 53 2.0E-29 T 23-10-2018 A3L08_08245 679a6a6759b3085ee16569d4b4d94b19 53 Pfam PF00301 Rubredoxin 3 49 7.4E-26 T 23-10-2018 IPR024935 Rubredoxin domain GO:0005506 A3L08_02035 da60aff179c2450a1366cdd5d4df6d7d 354 Gene3D G3DSA:3.40.50.300 104 354 1.4E-84 T 23-10-2018 A3L08_02035 da60aff179c2450a1366cdd5d4df6d7d 354 Hamap MF_00348 DNA repair and recombination protein RadA [radA]. 39 354 81.054 T 23-10-2018 IPR011938 DNA recombination/repair protein RadA GO:0003684|GO:0005524|GO:0006281|GO:0006310|GO:0008094 A3L08_02035 da60aff179c2450a1366cdd5d4df6d7d 354 Pfam PF08423 Rad51 102 354 3.5E-91 T 23-10-2018 IPR013632 DNA recombination and repair protein Rad51-like, C-terminal Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579 A3L08_02035 da60aff179c2450a1366cdd5d4df6d7d 354 SUPERFAMILY SSF47794 38 98 2.04E-13 T 23-10-2018 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 A3L08_02035 da60aff179c2450a1366cdd5d4df6d7d 354 SUPERFAMILY SSF52540 116 352 2.81E-59 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_02035 da60aff179c2450a1366cdd5d4df6d7d 354 TIGRFAM TIGR02236 recomb_radA: DNA repair and recombination protein RadA 42 354 4.2E-164 T 23-10-2018 IPR011938 DNA recombination/repair protein RadA GO:0003684|GO:0005524|GO:0006281|GO:0006310|GO:0008094 A3L08_02035 da60aff179c2450a1366cdd5d4df6d7d 354 Gene3D G3DSA:1.10.150.20 40 103 2.2E-25 T 23-10-2018 A3L08_02035 da60aff179c2450a1366cdd5d4df6d7d 354 Pfam PF14520 Helix-hairpin-helix domain 40 95 3.3E-12 T 23-10-2018 A3L08_02035 da60aff179c2450a1366cdd5d4df6d7d 354 SMART SM00382 135 324 1.2E-10 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L08_02035 da60aff179c2450a1366cdd5d4df6d7d 354 PIRSF PIRSF005856 30 354 3.1E-135 T 23-10-2018 IPR016467 DNA recombination and repair protein, RecA-like Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579 A3L08_02035 da60aff179c2450a1366cdd5d4df6d7d 354 SMART SM00278 73 92 360.0 T 23-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A3L08_02035 da60aff179c2450a1366cdd5d4df6d7d 354 SMART SM00278 40 59 0.011 T 23-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A3L08_02290 a98090fbf66dc624989a8f77c23508ee 324 SUPERFAMILY SSF52402 26 258 1.61E-53 T 23-10-2018 A3L08_02290 a98090fbf66dc624989a8f77c23508ee 324 TIGRFAM TIGR00269 TIGR00269: TIGR00269 family protein 205 306 1.0E-37 T 23-10-2018 IPR000541 Cytoplasmic tRNA 2-thiolation protein 1 GO:0000049|GO:0002098|GO:0034227 Reactome: R-HSA-6782315 A3L08_02290 a98090fbf66dc624989a8f77c23508ee 324 Gene3D G3DSA:3.40.50.620 2 320 4.9E-85 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L08_02290 a98090fbf66dc624989a8f77c23508ee 324 PIRSF PIRSF004976 1 318 4.7E-111 T 23-10-2018 IPR035107 tRNA thiolation protein, TtcA/Ctu1 type GO:0008033 Reactome: R-HSA-6782315 A3L08_02290 a98090fbf66dc624989a8f77c23508ee 324 Pfam PF01171 PP-loop family 51 229 5.6E-14 T 23-10-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 A3L08_00110 6c5edea808f57d622607753def333266 169 ProSitePatterns PS00893 Nudix box signature. 75 96 - T 23-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 A3L08_00110 6c5edea808f57d622607753def333266 169 Pfam PF00293 NUDIX domain 46 164 6.5E-24 T 23-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 A3L08_00110 6c5edea808f57d622607753def333266 169 Gene3D G3DSA:3.90.79.10 40 169 5.9E-43 T 23-10-2018 A3L08_00110 6c5edea808f57d622607753def333266 169 SUPERFAMILY SSF55811 37 166 5.01E-34 T 23-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 A3L08_00110 6c5edea808f57d622607753def333266 169 PRINTS PR00502 NUDIX hydrolase family signature 84 99 1.5E-7 T 23-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 A3L08_00110 6c5edea808f57d622607753def333266 169 PRINTS PR00502 NUDIX hydrolase family signature 70 84 1.5E-7 T 23-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 A3L08_03525 4ec09032ecfeba9a607f30530fd7dbb5 210 SUPERFAMILY SSF53335 3 201 5.32E-37 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L08_03525 4ec09032ecfeba9a607f30530fd7dbb5 210 Gene3D G3DSA:3.40.50.150 1 206 1.6E-68 T 23-10-2018 A3L08_03525 4ec09032ecfeba9a607f30530fd7dbb5 210 Pfam PF05175 Methyltransferase small domain 40 127 1.1E-14 T 23-10-2018 IPR007848 Methyltransferase small domain GO:0008168 A3L08_03525 4ec09032ecfeba9a607f30530fd7dbb5 210 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 115 121 - T 23-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 A3L08_07540 a1bc754616840e916b0d39bc965aa3d6 311 Pfam PF17125 N-terminal domain of 16S rRNA methyltransferase RsmF 12 97 3.4E-17 T 23-10-2018 IPR031341 Ribosomal RNA small subunit methyltransferase F, N-terminal Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 A3L08_07540 a1bc754616840e916b0d39bc965aa3d6 311 TIGRFAM TIGR00446 nop2p: NOL1/NOP2/sun family putative RNA methylase 39 306 1.1E-91 T 23-10-2018 IPR011023 Nop2p GO:0003723|GO:0006364|GO:0008757 Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 A3L08_07540 a1bc754616840e916b0d39bc965aa3d6 311 SUPERFAMILY SSF53335 21 306 1.02E-60 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L08_07540 a1bc754616840e916b0d39bc965aa3d6 311 Gene3D G3DSA:3.30.70.3130 3 96 8.2E-18 T 23-10-2018 A3L08_07540 a1bc754616840e916b0d39bc965aa3d6 311 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 228 244 1.2E-23 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L08_07540 a1bc754616840e916b0d39bc965aa3d6 311 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 83 97 1.2E-23 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L08_07540 a1bc754616840e916b0d39bc965aa3d6 311 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 112 122 1.2E-23 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L08_07540 a1bc754616840e916b0d39bc965aa3d6 311 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 289 306 1.2E-23 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L08_07540 a1bc754616840e916b0d39bc965aa3d6 311 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 178 190 1.2E-23 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L08_07540 a1bc754616840e916b0d39bc965aa3d6 311 Gene3D G3DSA:3.40.50.150 101 311 7.6E-72 T 23-10-2018 A3L08_07540 a1bc754616840e916b0d39bc965aa3d6 311 Pfam PF01189 16S rRNA methyltransferase RsmB/F 101 304 2.3E-52 T 23-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 A3L08_08675 52a827282945a150dd772a274439375a 441 Pfam PF03352 Methyladenine glycosylase 219 348 7.8E-17 T 23-10-2018 IPR005019 Methyladenine glycosylase GO:0006284|GO:0008725 A3L08_08675 52a827282945a150dd772a274439375a 441 Gene3D G3DSA:1.10.340.30 214 356 1.0E-20 T 23-10-2018 A3L08_08675 52a827282945a150dd772a274439375a 441 SUPERFAMILY SSF48150 219 355 6.42E-24 T 23-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 A3L08_03150 5407160600210f1d9b668779894113a9 59 Pfam PF07754 Domain of unknown function (DUF1610) 10 33 2.5E-14 T 23-10-2018 IPR011668 Domain of unknown function DUF1610 A3L08_07965 0c3babe8f10326c1452b4b813cf7f218 216 SUPERFAMILY SSF52833 1 215 1.17E-63 T 23-10-2018 IPR036249 Thioredoxin-like superfamily A3L08_07965 0c3babe8f10326c1452b4b813cf7f218 216 Pfam PF00578 AhpC/TSA family 4 134 7.2E-33 T 23-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A3L08_07965 0c3babe8f10326c1452b4b813cf7f218 216 Gene3D G3DSA:3.40.30.10 1 144 1.0E-45 T 23-10-2018 A3L08_07965 0c3babe8f10326c1452b4b813cf7f218 216 Gene3D G3DSA:3.30.1020.10 145 216 1.2E-34 T 23-10-2018 A3L08_07965 0c3babe8f10326c1452b4b813cf7f218 216 Hamap MF_00401 Peroxiredoxin. 2 215 51.298 T 23-10-2018 IPR022915 Peroxiredoxin, TDXH subfamily GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 A3L08_07965 0c3babe8f10326c1452b4b813cf7f218 216 PIRSF PIRSF000239 1 215 3.4E-70 T 23-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A3L08_07965 0c3babe8f10326c1452b4b813cf7f218 216 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 155 195 1.5E-7 T 23-10-2018 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A3L08_07085 cf574bc84bda40202cdbcdd6d9de3442 792 SUPERFAMILY SSF53850 44 366 3.41E-14 T 23-10-2018 A3L08_07085 cf574bc84bda40202cdbcdd6d9de3442 792 Gene3D G3DSA:3.10.105.10 101 385 6.1E-15 T 23-10-2018 A3L08_07085 cf574bc84bda40202cdbcdd6d9de3442 792 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 45 273 6.9E-12 T 23-10-2018 IPR000914 Solute-binding protein family 5 domain A3L08_08030 240291a581909803098be6c0f65e33f2 76 Pfam PF09851 Short C-terminal domain 48 74 1.1E-8 T 23-10-2018 IPR018649 SHOCT domain A3L08_04480 8f73d670b95638ea47e7eae667a9348c 333 TIGRFAM TIGR00341 TIGR00341: TIGR00341 family protein 101 331 3.1E-40 T 23-10-2018 A3L08_04480 8f73d670b95638ea47e7eae667a9348c 333 Pfam PF04087 Domain of unknown function (DUF389) 146 284 2.4E-26 T 23-10-2018 IPR005240 Protein of unknown function DUF389 A3L08_09425 be0223947c68bed49c2376147ae9cfb0 837 SMART SM01072 116 200 5.8E-15 T 23-10-2018 IPR004201 CDC48, domain 2 A3L08_09425 be0223947c68bed49c2376147ae9cfb0 837 Pfam PF02359 Cell division protein 48 (CDC48), N-terminal domain 14 98 3.7E-29 T 23-10-2018 IPR003338 CDC48, N-terminal subdomain A3L08_09425 be0223947c68bed49c2376147ae9cfb0 837 TIGRFAM TIGR01243 CDC48: AAA family ATPase, CDC48 subfamily 13 823 0.0 T 23-10-2018 IPR005938 AAA ATPase, CDC48 family GO:0016787 Reactome: R-HSA-110320|Reactome: R-HSA-3371511|Reactome: R-HSA-382556|Reactome: R-HSA-532668|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5678895|Reactome: R-HSA-5689877|Reactome: R-HSA-5689896|Reactome: R-HSA-6798695|Reactome: R-HSA-8866654|Reactome: R-HSA-8876725 A3L08_09425 be0223947c68bed49c2376147ae9cfb0 837 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 583 712 2.2E-47 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A3L08_09425 be0223947c68bed49c2376147ae9cfb0 837 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 248 377 1.6E-50 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A3L08_09425 be0223947c68bed49c2376147ae9cfb0 837 ProSitePatterns PS00674 AAA-protein family signature. 683 701 - T 23-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 A3L08_09425 be0223947c68bed49c2376147ae9cfb0 837 SUPERFAMILY SSF50692 11 96 1.07E-26 T 23-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily A3L08_09425 be0223947c68bed49c2376147ae9cfb0 837 SUPERFAMILY SSF52540 206 529 3.73E-68 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_09425 be0223947c68bed49c2376147ae9cfb0 837 Pfam PF02933 Cell division protein 48 (CDC48), domain 2 120 200 9.3E-13 T 23-10-2018 IPR004201 CDC48, domain 2 A3L08_09425 be0223947c68bed49c2376147ae9cfb0 837 SMART SM00382 579 715 1.1E-23 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L08_09425 be0223947c68bed49c2376147ae9cfb0 837 SMART SM00382 244 380 1.6E-25 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L08_09425 be0223947c68bed49c2376147ae9cfb0 837 ProSitePatterns PS00674 AAA-protein family signature. 348 366 - T 23-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 A3L08_09425 be0223947c68bed49c2376147ae9cfb0 837 Gene3D G3DSA:1.10.8.60 379 414 5.1E-6 T 23-10-2018 A3L08_09425 be0223947c68bed49c2376147ae9cfb0 837 Gene3D G3DSA:3.40.50.300 203 378 4.6E-74 T 23-10-2018 A3L08_09425 be0223947c68bed49c2376147ae9cfb0 837 Gene3D G3DSA:3.40.50.300 538 712 1.3E-74 T 23-10-2018 A3L08_09425 be0223947c68bed49c2376147ae9cfb0 837 Gene3D G3DSA:2.40.40.20 8 98 1.0E-32 T 23-10-2018 A3L08_09425 be0223947c68bed49c2376147ae9cfb0 837 Gene3D G3DSA:1.10.8.60 714 822 7.4E-32 T 23-10-2018 A3L08_09425 be0223947c68bed49c2376147ae9cfb0 837 Gene3D G3DSA:1.10.8.60 449 535 5.1E-16 T 23-10-2018 A3L08_09425 be0223947c68bed49c2376147ae9cfb0 837 Pfam PF09336 Vps4 C terminal oligomerisation domain 780 818 1.7E-4 T 23-10-2018 IPR015415 Vps4 oligomerisation, C-terminal A3L08_09425 be0223947c68bed49c2376147ae9cfb0 837 SUPERFAMILY SSF52540 541 817 2.74E-80 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_09425 be0223947c68bed49c2376147ae9cfb0 837 SMART SM01073 14 98 3.8E-36 T 23-10-2018 IPR003338 CDC48, N-terminal subdomain A3L08_09425 be0223947c68bed49c2376147ae9cfb0 837 SUPERFAMILY SSF54585 98 213 1.99E-17 T 23-10-2018 IPR029067 CDC48 domain 2-like superfamily A3L08_08805 00fe86abdfd58004f4da2588865ac340 67 Hamap MF_00773 50S ribosomal protein L24e [rpl24e]. 2 55 26.979 T 23-10-2018 IPR023438 Ribosomal protein L24e GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L08_08805 00fe86abdfd58004f4da2588865ac340 67 Pfam PF01246 Ribosomal protein L24e 3 60 3.1E-25 T 23-10-2018 IPR000988 Ribosomal protein L24e-related A3L08_08805 00fe86abdfd58004f4da2588865ac340 67 SMART SM00746 7 45 2.8E-11 T 23-10-2018 IPR011017 TRASH domain A3L08_08805 00fe86abdfd58004f4da2588865ac340 67 Gene3D G3DSA:2.30.170.20 2 66 5.4E-27 T 23-10-2018 IPR038630 Ribosomal protein L24e/L24 superfamily A3L08_08805 00fe86abdfd58004f4da2588865ac340 67 SUPERFAMILY SSF57716 6 56 3.35E-21 T 23-10-2018 A3L08_08805 00fe86abdfd58004f4da2588865ac340 67 ProSitePatterns PS01073 Ribosomal protein L24e signature. 9 26 - T 23-10-2018 IPR023442 Ribosomal protein L24e, conserved site A3L08_00130 ac175632c7b6fbd6e57b9f2db998a5c3 225 Pfam PF01902 Diphthamide synthase 1 219 9.5E-88 T 23-10-2018 IPR002761 Diphthamide synthase domain MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 A3L08_00130 ac175632c7b6fbd6e57b9f2db998a5c3 225 SUPERFAMILY SSF52402 1 221 3.2E-75 T 23-10-2018 A3L08_00130 ac175632c7b6fbd6e57b9f2db998a5c3 225 PIRSF PIRSF039123 1 225 1.4E-80 T 23-10-2018 IPR030662 Diphthine--ammonia ligase/Uncharacterised protein MJ0570 MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 A3L08_00130 ac175632c7b6fbd6e57b9f2db998a5c3 225 Gene3D G3DSA:3.40.50.620 1 135 2.2E-48 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L08_00130 ac175632c7b6fbd6e57b9f2db998a5c3 225 TIGRFAM TIGR00289 TIGR00289: TIGR00289 family protein 1 224 8.5E-94 T 23-10-2018 IPR005237 Uncharacterised protein MJ0570 A3L08_00130 ac175632c7b6fbd6e57b9f2db998a5c3 225 TIGRFAM TIGR00290 MJ0570_dom: MJ0570-related uncharacterized domain 1 220 1.7E-86 T 23-10-2018 IPR002761 Diphthamide synthase domain MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 A3L08_00130 ac175632c7b6fbd6e57b9f2db998a5c3 225 Gene3D G3DSA:3.90.1490.10 137 225 1.2E-32 T 23-10-2018 A3L08_00130 ac175632c7b6fbd6e57b9f2db998a5c3 225 TIGRFAM TIGR03679 arCOG00187: arCOG00187 universal archaeal metal-binding-domain/4Fe-4S-binding-domain containing ABC transporter, ATP-binding protein 4 211 1.6E-88 T 23-10-2018 IPR022427 Uncharacterised protein MJ0570, ATP-binding A3L08_03910 0dab938aa7ed0e1d4dce31d15c2df95c 125 Pfam PF04277 Oxaloacetate decarboxylase, gamma chain 6 82 1.9E-16 T 23-10-2018 IPR005899 Sodium ion-translocating decarboxylase GO:0008948|GO:0015081|GO:0016020|GO:0036376 KEGG: 00620+4.1.1.3 A3L08_03910 0dab938aa7ed0e1d4dce31d15c2df95c 125 PIRSF PIRSF018867 1 122 5.1E-30 T 23-10-2018 IPR014497 Methylmalonyl-CoA decarboxylase, delta subunit A3L08_03910 0dab938aa7ed0e1d4dce31d15c2df95c 125 TIGRFAM TIGR01195 oadG_fam: sodium pump decarboxylases, gamma subunit 4 84 8.8E-15 T 23-10-2018 IPR005899 Sodium ion-translocating decarboxylase GO:0008948|GO:0015081|GO:0016020|GO:0036376 KEGG: 00620+4.1.1.3 A3L08_02115 39e1233842a9b3c98fd61034c3e59366 469 Gene3D G3DSA:3.40.50.261 302 467 2.5E-44 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A3L08_02115 39e1233842a9b3c98fd61034c3e59366 469 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 161 297 7.6E-58 T 23-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain A3L08_02115 39e1233842a9b3c98fd61034c3e59366 469 Pfam PF13380 CoA binding domain 13 139 6.6E-22 T 23-10-2018 IPR003781 CoA-binding GO:0048037 A3L08_02115 39e1233842a9b3c98fd61034c3e59366 469 SUPERFAMILY SSF52210 136 298 5.23E-43 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A3L08_02115 39e1233842a9b3c98fd61034c3e59366 469 SUPERFAMILY SSF51735 6 135 8.22E-36 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L08_02115 39e1233842a9b3c98fd61034c3e59366 469 SMART SM00881 9 107 1.3E-37 T 23-10-2018 IPR003781 CoA-binding GO:0048037 A3L08_02115 39e1233842a9b3c98fd61034c3e59366 469 Gene3D G3DSA:3.40.50.720 4 134 7.6E-43 T 23-10-2018 A3L08_02115 39e1233842a9b3c98fd61034c3e59366 469 SUPERFAMILY SSF52210 304 463 3.92E-35 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A3L08_02115 39e1233842a9b3c98fd61034c3e59366 469 Gene3D G3DSA:3.40.50.261 136 300 1.5E-60 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A3L08_04085 72a383adf90e5ccef49222bb98304890 98 PIRSF PIRSF037511 5 97 7.4E-26 T 23-10-2018 IPR005872 Archaeal/bacterial translation initiation factor SUI1 GO:0003743 A3L08_04085 72a383adf90e5ccef49222bb98304890 98 TIGRFAM TIGR01158 SUI1_rel: putative translation initiation factor SUI1 4 97 2.6E-36 T 23-10-2018 IPR005872 Archaeal/bacterial translation initiation factor SUI1 GO:0003743 A3L08_04085 72a383adf90e5ccef49222bb98304890 98 Gene3D G3DSA:3.30.780.10 20 98 3.5E-29 T 23-10-2018 A3L08_04085 72a383adf90e5ccef49222bb98304890 98 Hamap MF_00604 Protein translation factor SUI1 homolog. 2 93 26.744 T 23-10-2018 IPR022851 Translation factor SUI1 homolog, archaea A3L08_04085 72a383adf90e5ccef49222bb98304890 98 SUPERFAMILY SSF55159 5 90 1.57E-24 T 23-10-2018 IPR036877 SUI1 domain superfamily GO:0003743|GO:0006413 A3L08_04085 72a383adf90e5ccef49222bb98304890 98 Pfam PF01253 Translation initiation factor SUI1 20 90 9.0E-21 T 23-10-2018 IPR001950 SUI1 domain GO:0003743|GO:0006413 A3L08_01315 57c74d98c5d5b80cedd9b946ecfab279 394 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 264 367 7.8E-34 T 23-10-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II A3L08_01315 57c74d98c5d5b80cedd9b946ecfab279 394 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 19 241 1.8E-78 T 23-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 A3L08_01315 57c74d98c5d5b80cedd9b946ecfab279 394 Gene3D G3DSA:3.40.50.920 254 394 2.8E-45 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A3L08_01315 57c74d98c5d5b80cedd9b946ecfab279 394 Gene3D G3DSA:3.40.50.970 6 253 1.4E-98 T 23-10-2018 A3L08_01315 57c74d98c5d5b80cedd9b946ecfab279 394 SUPERFAMILY SSF52518 7 252 9.57E-70 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold A3L08_01315 57c74d98c5d5b80cedd9b946ecfab279 394 SUPERFAMILY SSF52922 255 376 7.33E-36 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A3L08_05035 60078b06a3947cf50a72b27e249e818d 1122 Pfam PF04566 RNA polymerase Rpb2, domain 4 521 584 3.7E-19 T 23-10-2018 IPR007646 RNA polymerase Rpb2, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L08_05035 60078b06a3947cf50a72b27e249e818d 1122 Gene3D G3DSA:3.90.1100.10 21 177 3.4E-12 T 23-10-2018 A3L08_05035 60078b06a3947cf50a72b27e249e818d 1122 Pfam PF04567 RNA polymerase Rpb2, domain 5 605 637 1.3E-8 T 23-10-2018 IPR007647 RNA polymerase Rpb2, domain 5 GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L08_05035 60078b06a3947cf50a72b27e249e818d 1122 Pfam PF04561 RNA polymerase Rpb2, domain 2 175 348 1.4E-41 T 23-10-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L08_05035 60078b06a3947cf50a72b27e249e818d 1122 Pfam PF00562 RNA polymerase Rpb2, domain 6 653 1025 6.5E-132 T 23-10-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L08_05035 60078b06a3947cf50a72b27e249e818d 1122 Gene3D G3DSA:3.90.1800.10 1012 1120 5.8E-41 T 23-10-2018 A3L08_05035 60078b06a3947cf50a72b27e249e818d 1122 Gene3D G3DSA:2.40.50.150 683 874 2.3E-145 T 23-10-2018 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L08_05035 60078b06a3947cf50a72b27e249e818d 1122 Pfam PF04565 RNA polymerase Rpb2, domain 3 424 488 4.9E-30 T 23-10-2018 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L08_05035 60078b06a3947cf50a72b27e249e818d 1122 Pfam PF04563 RNA polymerase beta subunit 28 381 1.0E-54 T 23-10-2018 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L08_05035 60078b06a3947cf50a72b27e249e818d 1122 Gene3D G3DSA:2.40.270.10 653 1011 2.3E-145 T 23-10-2018 IPR037033 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L08_05035 60078b06a3947cf50a72b27e249e818d 1122 Gene3D G3DSA:3.90.1100.10 337 509 2.8E-55 T 23-10-2018 A3L08_05035 60078b06a3947cf50a72b27e249e818d 1122 Pfam PF04560 RNA polymerase Rpb2, domain 7 1027 1116 7.1E-31 T 23-10-2018 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L08_05035 60078b06a3947cf50a72b27e249e818d 1122 TIGRFAM TIGR03670 rpoB_arch: DNA-directed RNA polymerase subunit B 521 1121 0.0 T 23-10-2018 IPR019969 DNA-directed RNA polymerase subunit B (Rpo2) GO:0003677|GO:0003899|GO:0006351|GO:0008270 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L08_05035 60078b06a3947cf50a72b27e249e818d 1122 ProSitePatterns PS01166 RNA polymerases beta chain signature. 878 890 - T 23-10-2018 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L08_05035 60078b06a3947cf50a72b27e249e818d 1122 Gene3D G3DSA:3.90.1110.10 178 336 2.3E-59 T 23-10-2018 IPR037034 RNA polymerase Rpb2, domain 2 superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L08_05035 60078b06a3947cf50a72b27e249e818d 1122 SUPERFAMILY SSF64484 12 1118 0.0 T 23-10-2018 A3L08_04920 60aca0e91aa83c594177be56de8aef84 418 Gene3D G3DSA:1.20.1250.20 3 207 1.2E-15 T 23-10-2018 A3L08_04920 60aca0e91aa83c594177be56de8aef84 418 SUPERFAMILY SSF103473 7 412 7.59E-45 T 23-10-2018 IPR036259 MFS transporter superfamily A3L08_04920 60aca0e91aa83c594177be56de8aef84 418 Gene3D G3DSA:1.20.1250.20 216 417 3.2E-19 T 23-10-2018 A3L08_04920 60aca0e91aa83c594177be56de8aef84 418 Pfam PF07690 Major Facilitator Superfamily 15 247 1.1E-16 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A3L08_09070 b08b813b0762aae3872796c85e70562a 794 Gene3D G3DSA:1.20.1320.20 213 339 1.1E-98 T 23-10-2018 A3L08_09070 b08b813b0762aae3872796c85e70562a 794 Gene3D G3DSA:3.40.50.300 210 479 1.1E-98 T 23-10-2018 A3L08_09070 b08b813b0762aae3872796c85e70562a 794 Pfam PF02732 ERCC4 domain 586 704 1.4E-28 T 23-10-2018 IPR006166 ERCC4 domain GO:0003677|GO:0004518 Reactome: R-HSA-6783310 A3L08_09070 b08b813b0762aae3872796c85e70562a 794 Gene3D G3DSA:3.40.50.300 3 200 4.1E-71 T 23-10-2018 A3L08_09070 b08b813b0762aae3872796c85e70562a 794 SUPERFAMILY SSF47781 721 790 5.19E-16 T 23-10-2018 IPR010994 RuvA domain 2-like A3L08_09070 b08b813b0762aae3872796c85e70562a 794 SMART SM00278 734 753 850.0 T 23-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A3L08_09070 b08b813b0762aae3872796c85e70562a 794 SMART SM00278 766 785 0.021 T 23-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A3L08_09070 b08b813b0762aae3872796c85e70562a 794 SMART SM00487 7 202 2.4E-30 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A3L08_09070 b08b813b0762aae3872796c85e70562a 794 Pfam PF12826 Helix-hairpin-helix motif 738 789 5.8E-10 T 23-10-2018 A3L08_09070 b08b813b0762aae3872796c85e70562a 794 Pfam PF00270 DEAD/DEAH box helicase 15 147 4.5E-19 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A3L08_09070 b08b813b0762aae3872796c85e70562a 794 Pfam PF00271 Helicase conserved C-terminal domain 342 461 1.1E-22 T 23-10-2018 IPR001650 Helicase, C-terminal A3L08_09070 b08b813b0762aae3872796c85e70562a 794 SMART SM00891 583 663 1.2E-31 T 23-10-2018 IPR006166 ERCC4 domain GO:0003677|GO:0004518 Reactome: R-HSA-6783310 A3L08_09070 b08b813b0762aae3872796c85e70562a 794 SUPERFAMILY SSF52980 582 711 4.02E-38 T 23-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 A3L08_09070 b08b813b0762aae3872796c85e70562a 794 Gene3D G3DSA:3.40.50.10130 579 720 1.9E-52 T 23-10-2018 A3L08_09070 b08b813b0762aae3872796c85e70562a 794 SUPERFAMILY SSF52540 53 481 2.17E-57 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_09070 b08b813b0762aae3872796c85e70562a 794 Gene3D G3DSA:1.10.150.20 721 794 3.6E-23 T 23-10-2018 A3L08_09070 b08b813b0762aae3872796c85e70562a 794 SMART SM00490 373 462 1.4E-23 T 23-10-2018 IPR001650 Helicase, C-terminal A3L08_04055 7c49a2586fdc638f89194fec3af6a765 86 ProSitePatterns PS00050 Ribosomal protein L23 signature. 64 79 - T 23-10-2018 IPR001014 Ribosomal protein L23/L25, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_04055 7c49a2586fdc638f89194fec3af6a765 86 TIGRFAM TIGR03636 uL23_arch: ribosomal protein uL23 10 86 7.4E-39 T 23-10-2018 IPR019985 Ribosomal protein L23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_04055 7c49a2586fdc638f89194fec3af6a765 86 SUPERFAMILY SSF54189 4 78 2.3E-27 T 23-10-2018 IPR012678 Ribosomal protein L23/L15e core domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L08_04055 7c49a2586fdc638f89194fec3af6a765 86 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 4 82 14.648 T 23-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 A3L08_04055 7c49a2586fdc638f89194fec3af6a765 86 Pfam PF00276 Ribosomal protein L23 5 73 5.7E-19 T 23-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 A3L08_04055 7c49a2586fdc638f89194fec3af6a765 86 Hamap MF_01369_A 50S ribosomal protein L23 [rplW]. 6 86 27.55 T 23-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 A3L08_04055 7c49a2586fdc638f89194fec3af6a765 86 Gene3D G3DSA:3.30.70.330 1 86 7.2E-37 T 23-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily A3L08_00940 939044adeb1f530cd26583eabbf13668 211 Gene3D G3DSA:3.60.15.10 1 201 1.4E-48 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L08_00940 939044adeb1f530cd26583eabbf13668 211 Pfam PF13483 Beta-lactamase superfamily domain 3 175 2.2E-28 T 23-10-2018 A3L08_00940 939044adeb1f530cd26583eabbf13668 211 SUPERFAMILY SSF56281 1 197 1.16E-36 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L08_00940 939044adeb1f530cd26583eabbf13668 211 SMART SM00849 7 175 2.8E-18 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L08_06780 5ca2bafb6835bdd5da934dca965b8729 396 Gene3D G3DSA:3.40.50.920 283 395 1.7E-22 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A3L08_06780 5ca2bafb6835bdd5da934dca965b8729 396 SUPERFAMILY SSF52518 23 277 7.36E-67 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold A3L08_06780 5ca2bafb6835bdd5da934dca965b8729 396 Gene3D G3DSA:3.40.50.970 10 211 8.7E-77 T 23-10-2018 A3L08_06780 5ca2bafb6835bdd5da934dca965b8729 396 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 34 270 1.1E-76 T 23-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 A3L08_06780 5ca2bafb6835bdd5da934dca965b8729 396 SUPERFAMILY SSF52922 286 393 7.85E-23 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A3L08_06780 5ca2bafb6835bdd5da934dca965b8729 396 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 294 388 3.7E-19 T 23-10-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II A3L08_05170 1517a53ca97502eecfd5b4682683b0a8 268 SUPERFAMILY SSF52540 1 225 2.87E-64 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_05170 1517a53ca97502eecfd5b4682683b0a8 268 TIGRFAM TIGR01166 cbiO: cobalt ABC transporter, ATP-binding protein 13 194 7.5E-68 T 23-10-2018 IPR005876 Cobalt transport protein ATP-binding subunit GO:0006824 A3L08_05170 1517a53ca97502eecfd5b4682683b0a8 268 Pfam PF00005 ABC transporter 17 162 6.7E-29 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L08_05170 1517a53ca97502eecfd5b4682683b0a8 268 Gene3D G3DSA:3.40.50.300 1 243 1.2E-72 T 23-10-2018 A3L08_05170 1517a53ca97502eecfd5b4682683b0a8 268 SMART SM00382 26 217 5.4E-12 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L08_05170 1517a53ca97502eecfd5b4682683b0a8 268 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L08_08420 ee2252d704638e7ec2d228f968e89578 281 Pfam PF01791 DeoC/LacD family aldolase 24 251 1.2E-34 T 23-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 A3L08_08420 ee2252d704638e7ec2d228f968e89578 281 PIRSF PIRSF038992 4 280 1.7E-91 T 23-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 A3L08_08420 ee2252d704638e7ec2d228f968e89578 281 SUPERFAMILY SSF51569 8 266 2.64E-69 T 23-10-2018 A3L08_08420 ee2252d704638e7ec2d228f968e89578 281 SMART SM01133 23 251 5.3E-43 T 23-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 A3L08_08420 ee2252d704638e7ec2d228f968e89578 281 Gene3D G3DSA:3.20.20.70 2 279 4.1E-84 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L08_03035 1b7065f7e30e96fa613d298f89e50997 352 TIGRFAM TIGR01208 rmlA_long: glucose-1-phosphate thymidylyltransferase 2 352 6.2E-161 T 23-10-2018 IPR005908 Glucose-1-phosphate thymidylyltransferase, long form A3L08_03035 1b7065f7e30e96fa613d298f89e50997 352 Gene3D G3DSA:3.90.550.10 1 239 5.2E-65 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L08_03035 1b7065f7e30e96fa613d298f89e50997 352 Pfam PF00483 Nucleotidyl transferase 2 234 1.1E-48 T 23-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 A3L08_03035 1b7065f7e30e96fa613d298f89e50997 352 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 254 282 1.3E-5 T 23-10-2018 IPR001451 Hexapeptide repeat A3L08_03035 1b7065f7e30e96fa613d298f89e50997 352 Gene3D G3DSA:2.160.10.10 240 350 1.4E-14 T 23-10-2018 A3L08_03035 1b7065f7e30e96fa613d298f89e50997 352 SUPERFAMILY SSF53448 1 304 3.29E-73 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L08_05085 3a0ee11fb3a4522a72d57c61c8a592be 422 Hamap MF_02096 DNA repair protein. 1 407 40.157 T 23-10-2018 IPR033167 Archaeal Nre GO:0006281 A3L08_05085 3a0ee11fb3a4522a72d57c61c8a592be 422 Pfam PF04895 Archaeal Nre, C-terminal 297 407 1.8E-38 T 23-10-2018 IPR006979 Archaeal Nre, C-terminal A3L08_05085 3a0ee11fb3a4522a72d57c61c8a592be 422 Pfam PF04894 Archaeal Nre, N-terminal 20 285 4.5E-104 T 23-10-2018 IPR006978 Archaeal Nre, N-terminal A3L08_08655 090831f555c564e8e07de2fe467d74fb 517 SUPERFAMILY SSF56281 1 514 9.76E-39 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L08_08655 090831f555c564e8e07de2fe467d74fb 517 Pfam PF00753 Metallo-beta-lactamase superfamily 88 116 1.2E-4 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L08_00970 b17bb47ba1bc43795e21a40626d0cf40 337 Gene3D G3DSA:3.40.50.150 150 337 3.0E-35 T 23-10-2018 A3L08_00970 b17bb47ba1bc43795e21a40626d0cf40 337 Pfam PF02475 Met-10+ like-protein 89 266 4.7E-36 T 23-10-2018 IPR030382 SAM-dependent methyltransferase TRM5/TYW2-type Reactome: R-HSA-6782861 A3L08_00970 b17bb47ba1bc43795e21a40626d0cf40 337 Gene3D G3DSA:3.30.300.110 64 146 1.2E-12 T 23-10-2018 A3L08_00970 b17bb47ba1bc43795e21a40626d0cf40 337 SUPERFAMILY SSF53335 88 335 8.07E-47 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L08_04330 d122119f51e4e46d1d3c31575c6fefc5 79 SUPERFAMILY SSF54909 3 76 1.88E-16 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel A3L08_04330 d122119f51e4e46d1d3c31575c6fefc5 79 Pfam PF01037 Lrp/AsnC ligand binding domain 6 74 5.5E-18 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A3L08_04330 d122119f51e4e46d1d3c31575c6fefc5 79 Gene3D G3DSA:3.30.70.920 1 74 4.5E-21 T 23-10-2018 A3L08_02010 e749685923a8c4a8bcd21dc53eb4e984 1316 PIRSF PIRSF016275 1 1212 0.0 T 23-10-2018 IPR004475 DNA polymerase II large subunit DP2 GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A3L08_02010 e749685923a8c4a8bcd21dc53eb4e984 1316 TIGRFAM TIGR00354 polC: DNA polymerase II, large subunit DP2 9 1204 0.0 T 23-10-2018 IPR004475 DNA polymerase II large subunit DP2 GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A3L08_02010 e749685923a8c4a8bcd21dc53eb4e984 1316 Hamap MF_00324 DNA polymerase II large subunit [polC]. 1 1226 522.091 T 23-10-2018 IPR004475 DNA polymerase II large subunit DP2 GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A3L08_02010 e749685923a8c4a8bcd21dc53eb4e984 1316 Pfam PF03833 DNA polymerase II large subunit DP2 13 961 0.0 T 23-10-2018 IPR016033 DNA polymerase II large subunit DP2, N-terminal KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A3L08_00770 37379190e7f772a42f39cbd85163c6e6 262 PIRSF PIRSF004853 1 253 1.1E-113 T 23-10-2018 IPR002855 Phosphopantoate/pantothenate synthetase A3L08_00770 37379190e7f772a42f39cbd85163c6e6 262 ProDom PD016827 ARCHAEA ST0532 APE1937 VNG0250C MM2281 PAE3406 AF0927 UNCHARACTERIZED C3_0043 MJ0209 70 251 2.0E-94 T 23-10-2018 IPR002855 Phosphopantoate/pantothenate synthetase A3L08_00770 37379190e7f772a42f39cbd85163c6e6 262 Gene3D G3DSA:3.40.50.12640 1 261 2.2E-122 T 23-10-2018 IPR038138 Phosphopantoate/pantothenate synthetase superfamily A3L08_00770 37379190e7f772a42f39cbd85163c6e6 262 Pfam PF02006 Phosphopantothenate/pantothenate synthetase 66 240 2.9E-76 T 23-10-2018 IPR002855 Phosphopantoate/pantothenate synthetase A3L08_02410 d298950f0ea9e46c064fc12dd047ca10 219 Gene3D G3DSA:3.40.50.11570 6 218 3.5E-45 T 23-10-2018 A3L08_02410 d298950f0ea9e46c064fc12dd047ca10 219 Pfam PF03192 Pyrococcus protein of unknown function, DUF257 11 214 8.1E-50 T 23-10-2018 IPR005489 Protein of unknown function DUF257 A3L08_00350 255f0d3e5457cc824ba01f0ffeb8d7c6 385 SUPERFAMILY SSF53756 2 382 2.34E-97 T 23-10-2018 A3L08_00350 255f0d3e5457cc824ba01f0ffeb8d7c6 385 Pfam PF00534 Glycosyl transferases group 1 189 358 2.3E-47 T 23-10-2018 IPR001296 Glycosyl transferase, family 1 A3L08_00350 255f0d3e5457cc824ba01f0ffeb8d7c6 385 Pfam PF13439 Glycosyltransferase Family 4 14 181 1.3E-27 T 23-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 A3L08_00350 255f0d3e5457cc824ba01f0ffeb8d7c6 385 Gene3D G3DSA:3.40.50.2000 5 367 1.2E-93 T 23-10-2018 A3L08_00350 255f0d3e5457cc824ba01f0ffeb8d7c6 385 Gene3D G3DSA:3.40.50.2000 179 366 1.2E-93 T 23-10-2018 A3L08_08960 78b9d6c773923acef4a4b6a03210630c 157 ProSitePatterns PS00519 AsnC-type HTH domain signature. 22 48 - T 23-10-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site A3L08_08960 78b9d6c773923acef4a4b6a03210630c 157 Gene3D G3DSA:3.30.70.920 56 149 2.4E-12 T 23-10-2018 A3L08_08960 78b9d6c773923acef4a4b6a03210630c 157 Pfam PF01037 Lrp/AsnC ligand binding domain 79 128 6.4E-7 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A3L08_08960 78b9d6c773923acef4a4b6a03210630c 157 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 4 20 1.8E-15 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L08_08960 78b9d6c773923acef4a4b6a03210630c 157 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 31 50 1.8E-15 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L08_08960 78b9d6c773923acef4a4b6a03210630c 157 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 20 31 1.8E-15 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L08_08960 78b9d6c773923acef4a4b6a03210630c 157 Gene3D G3DSA:1.10.10.10 2 55 1.9E-20 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L08_08960 78b9d6c773923acef4a4b6a03210630c 157 SUPERFAMILY SSF46785 4 63 2.46E-16 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L08_08960 78b9d6c773923acef4a4b6a03210630c 157 Pfam PF13412 Winged helix-turn-helix DNA-binding 5 51 9.8E-15 T 23-10-2018 A3L08_08960 78b9d6c773923acef4a4b6a03210630c 157 SUPERFAMILY SSF54909 67 148 2.41E-7 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel A3L08_08960 78b9d6c773923acef4a4b6a03210630c 157 SMART SM00344 4 112 3.1E-32 T 23-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A3L08_01440 ab030c132277b99c5a4b643e1242bb26 568 SUPERFAMILY SSF88697 512 566 1.55E-12 T 23-10-2018 IPR015947 PUA-like superfamily A3L08_01440 ab030c132277b99c5a4b643e1242bb26 568 SUPERFAMILY SSF52141 265 422 5.1E-40 T 23-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A3L08_01440 ab030c132277b99c5a4b643e1242bb26 568 Gene3D G3DSA:3.40.50.10630 252 423 1.4E-46 T 23-10-2018 A3L08_01440 ab030c132277b99c5a4b643e1242bb26 568 SMART SM00359 502 568 4.6E-8 T 23-10-2018 IPR002478 PUA domain GO:0003723 A3L08_01440 ab030c132277b99c5a4b643e1242bb26 568 Pfam PF01472 PUA domain 513 566 8.5E-10 T 23-10-2018 IPR002478 PUA domain GO:0003723 A3L08_01440 ab030c132277b99c5a4b643e1242bb26 568 SUPERFAMILY SSF51713 1 243 6.02E-21 T 23-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 A3L08_01440 ab030c132277b99c5a4b643e1242bb26 568 TIGRFAM TIGR00451 unchar_dom_2: uncharacterized domain 2 511 565 4.9E-9 T 23-10-2018 IPR004521 Uncharacterised domain CHP00451 GO:0003723 A3L08_01440 ab030c132277b99c5a4b643e1242bb26 568 SUPERFAMILY SSF88802 247 500 1.63E-16 T 23-10-2018 A3L08_01440 ab030c132277b99c5a4b643e1242bb26 568 Gene3D G3DSA:2.30.130.10 502 568 2.8E-23 T 23-10-2018 IPR036974 PUA domain superfamily GO:0003723 A3L08_09395 0f897e2da26469ffe43e29c2910cc10d 387 SUPERFAMILY SSF48452 117 258 7.68E-6 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A3L08_03735 f68a596d660c98da77f223492fe10b34 234 Gene3D G3DSA:1.10.150.400 14 92 3.2E-65 T 23-10-2018 A3L08_03735 f68a596d660c98da77f223492fe10b34 234 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 1 12 2.1E-5 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L08_03735 f68a596d660c98da77f223492fe10b34 234 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 142 158 2.1E-5 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L08_03735 f68a596d660c98da77f223492fe10b34 234 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 160 180 2.1E-5 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L08_03735 f68a596d660c98da77f223492fe10b34 234 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 108 121 2.1E-5 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L08_03735 f68a596d660c98da77f223492fe10b34 234 SUPERFAMILY SSF56784 1 226 5.56E-32 T 23-10-2018 IPR036412 HAD-like superfamily A3L08_03735 f68a596d660c98da77f223492fe10b34 234 Gene3D G3DSA:3.40.50.1000 2 215 3.2E-65 T 23-10-2018 IPR023214 HAD superfamily A3L08_03735 f68a596d660c98da77f223492fe10b34 234 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 130 193 1.1E-6 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L08_03735 f68a596d660c98da77f223492fe10b34 234 Pfam PF13419 Haloacid dehalogenase-like hydrolase 43 199 2.1E-15 T 23-10-2018 A3L08_00555 6056cfd91aa2f167388ef11d963aa50c 418 Gene3D G3DSA:3.90.1150.10 34 409 1.5E-165 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A3L08_00555 6056cfd91aa2f167388ef11d963aa50c 418 Gene3D G3DSA:3.40.640.10 79 304 1.5E-165 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A3L08_00555 6056cfd91aa2f167388ef11d963aa50c 418 Pfam PF00155 Aminotransferase class I and II 44 405 1.1E-40 T 23-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A3L08_00555 6056cfd91aa2f167388ef11d963aa50c 418 SUPERFAMILY SSF53383 16 411 4.49E-121 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A3L08_09475 ea1bb36a367e62b02accfbaa09ede30d 150 ProDom PD003854 RIBOSOMAL 40S RIBONUCLEOPROTEIN S19 S19E 30S MULTIGENE FAMILY S19 SSU 3 115 2.0E-57 T 23-10-2018 IPR001266 Ribosomal protein S19e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_09475 ea1bb36a367e62b02accfbaa09ede30d 150 Hamap MF_01474 30S ribosomal protein S19e [rps19e]. 1 148 38.004 T 23-10-2018 IPR027548 Ribosomal protein S19e, archaeal GO:0003735|GO:0005840|GO:0006412 A3L08_09475 ea1bb36a367e62b02accfbaa09ede30d 150 SUPERFAMILY SSF46785 3 150 1.69E-61 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L08_09475 ea1bb36a367e62b02accfbaa09ede30d 150 Pfam PF01090 Ribosomal protein S19e 3 138 5.8E-59 T 23-10-2018 IPR001266 Ribosomal protein S19e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_09475 ea1bb36a367e62b02accfbaa09ede30d 150 Gene3D G3DSA:1.10.10.2700 1 150 1.3E-66 T 23-10-2018 IPR038111 Ribosomal protein S19e domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_09475 ea1bb36a367e62b02accfbaa09ede30d 150 ProSitePatterns PS00628 Ribosomal protein S19e signature. 87 106 - T 23-10-2018 IPR018277 Ribosomal protein S19e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_09475 ea1bb36a367e62b02accfbaa09ede30d 150 SMART SM01413 3 139 1.2E-91 T 23-10-2018 IPR001266 Ribosomal protein S19e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_03770 ec7a8a83e0c6f5f37527c8444d939b63 329 SUPERFAMILY SSF53774 2 327 3.53E-97 T 23-10-2018 IPR036152 Asparaginase/glutaminase-like superfamily Reactome: R-HSA-70614 A3L08_03770 ec7a8a83e0c6f5f37527c8444d939b63 329 TIGRFAM TIGR00519 asnASE_I: L-asparaginase, type I 3 326 1.3E-90 T 23-10-2018 IPR006033 L-asparaginase, type I GO:0004067|GO:0006520 Reactome: R-HSA-70614 A3L08_03770 ec7a8a83e0c6f5f37527c8444d939b63 329 PIRSF PIRSF001220 1 325 7.3E-92 T 23-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 A3L08_03770 ec7a8a83e0c6f5f37527c8444d939b63 329 PIRSF PIRSF500176 1 323 3.4E-96 T 23-10-2018 A3L08_03770 ec7a8a83e0c6f5f37527c8444d939b63 329 Gene3D G3DSA:3.40.50.40 201 327 7.8E-40 T 23-10-2018 IPR027473 L-asparaginase, C-terminal Reactome: R-HSA-70614 A3L08_03770 ec7a8a83e0c6f5f37527c8444d939b63 329 Pfam PF00710 Asparaginase, N-terminal 2 187 3.8E-61 T 23-10-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 A3L08_03770 ec7a8a83e0c6f5f37527c8444d939b63 329 ProSitePatterns PS00917 Asparaginase / glutaminase active site signature 2. 78 88 - T 23-10-2018 IPR027475 Asparaginase/glutaminase, active site 2 Reactome: R-HSA-70614 A3L08_03770 ec7a8a83e0c6f5f37527c8444d939b63 329 PRINTS PR00139 Asparaginase/glutaminase family signature 77 95 2.9E-13 T 23-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 A3L08_03770 ec7a8a83e0c6f5f37527c8444d939b63 329 PRINTS PR00139 Asparaginase/glutaminase family signature 251 269 2.9E-13 T 23-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 A3L08_03770 ec7a8a83e0c6f5f37527c8444d939b63 329 PRINTS PR00139 Asparaginase/glutaminase family signature 3 14 2.9E-13 T 23-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 A3L08_03770 ec7a8a83e0c6f5f37527c8444d939b63 329 ProSitePatterns PS00144 Asparaginase / glutaminase active site signature 1. 5 13 - T 23-10-2018 IPR020827 Asparaginase/glutaminase, active site 1 GO:0006520 A3L08_03770 ec7a8a83e0c6f5f37527c8444d939b63 329 Gene3D G3DSA:3.40.50.1170 1 199 1.2E-69 T 23-10-2018 IPR037152 L-asparaginase, N-terminal domain superfamily Reactome: R-HSA-70614 A3L08_03770 ec7a8a83e0c6f5f37527c8444d939b63 329 SMART SM00870 2 314 2.4E-117 T 23-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 A3L08_07370 46bc619700c55ccf1dad5f8df9ea1dc7 358 Gene3D G3DSA:1.10.3210.10 1 258 2.4E-75 T 23-10-2018 A3L08_07370 46bc619700c55ccf1dad5f8df9ea1dc7 358 Pfam PF01966 HD domain 50 125 4.2E-9 T 23-10-2018 IPR006674 HD domain A3L08_07370 46bc619700c55ccf1dad5f8df9ea1dc7 358 SMART SM00471 46 156 4.4E-13 T 23-10-2018 IPR003607 HD/PDEase domain A3L08_07370 46bc619700c55ccf1dad5f8df9ea1dc7 358 SUPERFAMILY SSF109604 1 341 2.83E-82 T 23-10-2018 A3L08_03555 d50e9fcd4705451dfa305aea9dbb6fd8 215 Pfam PF04256 Protein of unknown function (DUF434) 2 56 4.6E-24 T 23-10-2018 IPR007368 Protein of unknown function DUF434 A3L08_03555 d50e9fcd4705451dfa305aea9dbb6fd8 215 ProDom PD019177 PF1672 MJ0935 ST1363 PH1730 UNCHARACTERIZED ARCHAEAL 2 49 2.0E-14 T 23-10-2018 IPR007368 Protein of unknown function DUF434 A3L08_05645 3630c51fa5e428c4ae7aa4d9c6aa4fa5 289 Pfam PF12679 ABC-2 family transporter protein 6 288 1.1E-38 T 23-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 A3L08_03935 ca10a80793aca76011287da8efb10451 170 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 1 151 5.7E-33 T 23-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 A3L08_03935 ca10a80793aca76011287da8efb10451 170 SUPERFAMILY SSF56300 1 159 2.58E-39 T 23-10-2018 A3L08_03935 ca10a80793aca76011287da8efb10451 170 TIGRFAM TIGR00040 yfcE: phosphodiesterase, MJ0936 family 1 155 1.7E-38 T 23-10-2018 IPR000979 Phosphodiesterase MJ0936/Vps29 Reactome: R-HSA-3238698 A3L08_03935 ca10a80793aca76011287da8efb10451 170 ProSitePatterns PS01269 Uncharacterized protein family UPF0025 signature. 108 132 - T 23-10-2018 IPR020935 Phosphodiesterase YfcE, conserved site A3L08_03935 ca10a80793aca76011287da8efb10451 170 Gene3D G3DSA:3.60.21.10 1 159 1.7E-51 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like A3L08_07660 86b048d8a72c31f1e5dfd5763ee78684 890 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 43 54 - T 23-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L08_07660 86b048d8a72c31f1e5dfd5763ee78684 890 Hamap MF_02005 Valine--tRNA ligase [valS]. 2 795 29.07 T 23-10-2018 IPR022874 Valine-tRNA ligase, type 2 GO:0004832 KEGG: 00970+6.1.1.9 A3L08_07660 86b048d8a72c31f1e5dfd5763ee78684 890 Pfam PF08264 Anticodon-binding domain of tRNA 616 764 5.1E-38 T 23-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 A3L08_07660 86b048d8a72c31f1e5dfd5763ee78684 890 SUPERFAMILY SSF50677 187 335 8.76E-50 T 23-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 A3L08_07660 86b048d8a72c31f1e5dfd5763ee78684 890 TIGRFAM TIGR00422 valS: valine--tRNA ligase 3 866 2.3E-271 T 23-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 A3L08_07660 86b048d8a72c31f1e5dfd5763ee78684 890 Gene3D G3DSA:1.10.730.10 2 752 7.1E-242 T 23-10-2018 A3L08_07660 86b048d8a72c31f1e5dfd5763ee78684 890 Gene3D G3DSA:3.40.50.620 22 537 7.1E-242 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L08_07660 86b048d8a72c31f1e5dfd5763ee78684 890 PRINTS PR00986 Valyl-tRNA synthetase signature 36 47 2.2E-18 T 23-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 A3L08_07660 86b048d8a72c31f1e5dfd5763ee78684 890 PRINTS PR00986 Valyl-tRNA synthetase signature 343 356 2.2E-18 T 23-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 A3L08_07660 86b048d8a72c31f1e5dfd5763ee78684 890 PRINTS PR00986 Valyl-tRNA synthetase signature 488 506 2.2E-18 T 23-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 A3L08_07660 86b048d8a72c31f1e5dfd5763ee78684 890 PRINTS PR00986 Valyl-tRNA synthetase signature 450 471 2.2E-18 T 23-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 A3L08_07660 86b048d8a72c31f1e5dfd5763ee78684 890 PRINTS PR00986 Valyl-tRNA synthetase signature 225 242 2.2E-18 T 23-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 A3L08_07660 86b048d8a72c31f1e5dfd5763ee78684 890 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 14 572 1.1E-139 T 23-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L08_07660 86b048d8a72c31f1e5dfd5763ee78684 890 SUPERFAMILY SSF47323 588 827 2.43E-61 T 23-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L08_07660 86b048d8a72c31f1e5dfd5763ee78684 890 SUPERFAMILY SSF52374 3 581 2.92E-127 T 23-10-2018 A3L08_07660 86b048d8a72c31f1e5dfd5763ee78684 890 Gene3D G3DSA:3.90.740.10 170 337 7.1E-242 T 23-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 A3L08_05540 38ec16a2006811c1ec9743c97c0994f2 345 PIRSF PIRSF001123 1 344 2.1E-102 T 23-10-2018 IPR008007 Peptidase M42 A3L08_05540 38ec16a2006811c1ec9743c97c0994f2 345 Pfam PF05343 M42 glutamyl aminopeptidase 45 329 1.7E-97 T 23-10-2018 IPR008007 Peptidase M42 A3L08_05540 38ec16a2006811c1ec9743c97c0994f2 345 Gene3D G3DSA:2.40.30.40 68 160 1.4E-131 T 23-10-2018 IPR023367 Peptidase M42, domain 2 A3L08_05540 38ec16a2006811c1ec9743c97c0994f2 345 Gene3D G3DSA:3.40.630.10 7 332 1.4E-131 T 23-10-2018 A3L08_05540 38ec16a2006811c1ec9743c97c0994f2 345 SUPERFAMILY SSF101821 68 176 4.27E-27 T 23-10-2018 A3L08_05540 38ec16a2006811c1ec9743c97c0994f2 345 SUPERFAMILY SSF53187 4 339 3.39E-63 T 23-10-2018 A3L08_02425 004a14d87712749066460f66b7e62357 184 Pfam PF00571 CBS domain 50 100 4.7E-12 T 23-10-2018 IPR000644 CBS domain A3L08_02425 004a14d87712749066460f66b7e62357 184 Pfam PF00571 CBS domain 125 179 3.7E-10 T 23-10-2018 IPR000644 CBS domain A3L08_02425 004a14d87712749066460f66b7e62357 184 SMART SM00116 54 101 5.6E-4 T 23-10-2018 IPR000644 CBS domain A3L08_02425 004a14d87712749066460f66b7e62357 184 SMART SM00116 132 180 5.6E-6 T 23-10-2018 IPR000644 CBS domain A3L08_02425 004a14d87712749066460f66b7e62357 184 SUPERFAMILY SSF54631 35 179 4.07E-28 T 23-10-2018 A3L08_02425 004a14d87712749066460f66b7e62357 184 Gene3D G3DSA:3.10.580.10 3 102 9.3E-14 T 23-10-2018 A3L08_02425 004a14d87712749066460f66b7e62357 184 Gene3D G3DSA:3.10.580.10 104 182 1.0E-13 T 23-10-2018 A3L08_02300 55b16ab2e28670eefa1f090575df7ce9 300 Gene3D G3DSA:3.90.550.10 1 240 2.9E-75 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L08_02300 55b16ab2e28670eefa1f090575df7ce9 300 SUPERFAMILY SSF53448 4 217 1.5E-66 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L08_02300 55b16ab2e28670eefa1f090575df7ce9 300 Pfam PF00535 Glycosyl transferase family 2 7 167 2.8E-40 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A3L08_05820 38990fafdb5776cfd75a85aca227e506 136 Gene3D G3DSA:2.30.30.30 2 69 1.5E-27 T 23-10-2018 IPR014722 Ribosomal protein L2, domain 2 A3L08_05820 38990fafdb5776cfd75a85aca227e506 136 SUPERFAMILY SSF50249 71 133 2.91E-14 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L08_05820 38990fafdb5776cfd75a85aca227e506 136 ProSitePatterns PS00302 Eukaryotic initiation factor 5A hypusine signature. 35 42 - T 23-10-2018 IPR019769 Translation elongation factor, IF5A, hypusine site GO:0003723|GO:0003746|GO:0043022|GO:0045901|GO:0045905 A3L08_05820 38990fafdb5776cfd75a85aca227e506 136 SUPERFAMILY SSF50104 5 78 6.52E-20 T 23-10-2018 IPR008991 Translation protein SH3-like domain superfamily A3L08_05820 38990fafdb5776cfd75a85aca227e506 136 Hamap MF_00085 Translation initiation factor 5A [eif5a]. 3 133 34.747 T 23-10-2018 IPR022847 Translation elongation factor IF5A, archaeal A3L08_05820 38990fafdb5776cfd75a85aca227e506 136 Pfam PF01287 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold 70 134 3.1E-11 T 23-10-2018 IPR020189 Translation elongation factor, IF5A C-terminal GO:0003723|GO:0003746|GO:0006452|GO:0043022|GO:0045901|GO:0045905 A3L08_05820 38990fafdb5776cfd75a85aca227e506 136 Gene3D G3DSA:2.40.50.140 70 135 1.5E-29 T 23-10-2018 A3L08_05820 38990fafdb5776cfd75a85aca227e506 136 PIRSF PIRSF003025 1 136 1.4E-44 T 23-10-2018 IPR001884 Translation elongation factor IF5A-like GO:0003723|GO:0003746|GO:0043022|GO:0045901 A3L08_05820 38990fafdb5776cfd75a85aca227e506 136 TIGRFAM TIGR00037 eIF_5A: translation elongation factor IF5A 4 134 7.8E-48 T 23-10-2018 IPR001884 Translation elongation factor IF5A-like GO:0003723|GO:0003746|GO:0043022|GO:0045901 A3L08_05820 38990fafdb5776cfd75a85aca227e506 136 SMART SM01376 70 134 1.9E-17 T 23-10-2018 IPR020189 Translation elongation factor, IF5A C-terminal GO:0003723|GO:0003746|GO:0006452|GO:0043022|GO:0045901|GO:0045905 A3L08_03175 f4a0ea2ef958566e9e3e2cbc0e03ac75 195 Pfam PF02676 Methyltransferase TYW3 11 193 6.0E-47 T 23-10-2018 IPR003827 tRNA wybutosine-synthesizing protein MetaCyc: PWY-7286|Reactome: R-HSA-6782861 A3L08_03175 f4a0ea2ef958566e9e3e2cbc0e03ac75 195 SUPERFAMILY SSF111278 7 193 2.88E-62 T 23-10-2018 IPR036602 tRNA wybutosine-synthesizing-like superfamily MetaCyc: PWY-7286|Reactome: R-HSA-6782861 A3L08_03175 f4a0ea2ef958566e9e3e2cbc0e03ac75 195 Hamap MF_00266 tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase [taw3]. 9 195 30.986 T 23-10-2018 IPR022908 tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase GO:0008175|GO:0030488|GO:0031591 MetaCyc: PWY-7286 A3L08_03175 f4a0ea2ef958566e9e3e2cbc0e03ac75 195 Gene3D G3DSA:3.30.1960.10 2 195 4.4E-69 T 23-10-2018 IPR036602 tRNA wybutosine-synthesizing-like superfamily MetaCyc: PWY-7286|Reactome: R-HSA-6782861 A3L08_03720 51896f2dd1ff4086e5ac7bb4d7f7ed1f 774 SMART SM00486 133 550 2.5E-145 T 23-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A3L08_03720 51896f2dd1ff4086e5ac7bb4d7f7ed1f 774 Gene3D G3DSA:1.10.287.690 448 499 3.6E-24 T 23-10-2018 A3L08_03720 51896f2dd1ff4086e5ac7bb4d7f7ed1f 774 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 536 544 8.9E-10 T 23-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A3L08_03720 51896f2dd1ff4086e5ac7bb4d7f7ed1f 774 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 483 495 8.9E-10 T 23-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A3L08_03720 51896f2dd1ff4086e5ac7bb4d7f7ed1f 774 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 400 413 8.9E-10 T 23-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A3L08_03720 51896f2dd1ff4086e5ac7bb4d7f7ed1f 774 Gene3D G3DSA:1.10.132.60 607 773 2.2E-63 T 23-10-2018 A3L08_03720 51896f2dd1ff4086e5ac7bb4d7f7ed1f 774 Pfam PF03104 DNA polymerase family B, exonuclease domain 130 278 2.0E-34 T 23-10-2018 IPR006133 DNA-directed DNA polymerase, family B, exonuclease domain KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A3L08_03720 51896f2dd1ff4086e5ac7bb4d7f7ed1f 774 Pfam PF03104 DNA polymerase family B, exonuclease domain 23 129 1.5E-14 T 23-10-2018 IPR006133 DNA-directed DNA polymerase, family B, exonuclease domain KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A3L08_03720 51896f2dd1ff4086e5ac7bb4d7f7ed1f 774 Gene3D G3DSA:3.30.342.10 3 366 8.3E-174 T 23-10-2018 A3L08_03720 51896f2dd1ff4086e5ac7bb4d7f7ed1f 774 SUPERFAMILY SSF56672 349 759 1.5E-134 T 23-10-2018 A3L08_03720 51896f2dd1ff4086e5ac7bb4d7f7ed1f 774 ProSitePatterns PS00116 DNA polymerase family B signature. 538 546 - T 23-10-2018 IPR017964 DNA-directed DNA polymerase, family B, conserved site GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A3L08_03720 51896f2dd1ff4086e5ac7bb4d7f7ed1f 774 Pfam PF00136 DNA polymerase family B 352 746 1.9E-83 T 23-10-2018 IPR006134 DNA-directed DNA polymerase, family B, multifunctional domain GO:0000166|GO:0003677 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A3L08_03720 51896f2dd1ff4086e5ac7bb4d7f7ed1f 774 Gene3D G3DSA:3.30.420.10 131 347 8.3E-174 T 23-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 A3L08_03720 51896f2dd1ff4086e5ac7bb4d7f7ed1f 774 TIGRFAM TIGR00592 pol2: DNA polymerase (pol2) 2 491 1.2E-103 T 23-10-2018 A3L08_03720 51896f2dd1ff4086e5ac7bb4d7f7ed1f 774 TIGRFAM TIGR00592 pol2: DNA polymerase (pol2) 446 745 4.1E-114 T 23-10-2018 A3L08_03720 51896f2dd1ff4086e5ac7bb4d7f7ed1f 774 SUPERFAMILY SSF53098 1 346 1.05E-91 T 23-10-2018 IPR012337 Ribonuclease H-like superfamily A3L08_06230 50a8f959d46977f5c535d15c1fd21dad 176 PIRSF PIRSF019239 4 176 7.7E-55 T 23-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 A3L08_06230 50a8f959d46977f5c535d15c1fd21dad 176 Pfam PF01899 Na+/H+ ion antiporter subunit 15 157 3.2E-47 T 23-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 A3L08_04605 6f95e375e15fba2830823c1a70650240 206 SMART SM00471 30 147 1.8E-11 T 23-10-2018 IPR003607 HD/PDEase domain A3L08_04605 6f95e375e15fba2830823c1a70650240 206 Pfam PF01966 HD domain 35 137 9.1E-19 T 23-10-2018 IPR006674 HD domain A3L08_04605 6f95e375e15fba2830823c1a70650240 206 TIGRFAM TIGR00277 HDIG: HDIG domain 34 96 2.5E-8 T 23-10-2018 IPR006675 HDIG domain A3L08_04605 6f95e375e15fba2830823c1a70650240 206 SUPERFAMILY SSF109604 13 205 3.43E-61 T 23-10-2018 A3L08_04605 6f95e375e15fba2830823c1a70650240 206 Gene3D G3DSA:1.10.3210.50 13 206 6.8E-66 T 23-10-2018 A3L08_02495 bf3c81654fa626619985c5c09ac1f620 250 Gene3D G3DSA:3.40.1390.30 6 238 1.8E-74 T 23-10-2018 A3L08_02495 bf3c81654fa626619985c5c09ac1f620 250 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 5 237 4.4E-55 T 23-10-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 A3L08_02495 bf3c81654fa626619985c5c09ac1f620 250 TIGRFAM TIGR00486 YbgI_SA1388: dinuclear metal center protein, YbgI/SA1388 family 1 248 1.1E-57 T 23-10-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 A3L08_02495 bf3c81654fa626619985c5c09ac1f620 250 Gene3D G3DSA:3.40.1390.30 96 221 1.8E-74 T 23-10-2018 A3L08_02495 bf3c81654fa626619985c5c09ac1f620 250 SUPERFAMILY SSF102705 1 249 1.02E-66 T 23-10-2018 IPR036069 GTP cyclohydrolase 1 type 2/Nif3 superfamily A3L08_01190 27438dbfe01823ed529733d839c01f16 169 Gene3D G3DSA:1.10.10.10 63 150 1.5E-22 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L08_01190 27438dbfe01823ed529733d839c01f16 169 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 102 117 5.2E-9 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L08_01190 27438dbfe01823ed529733d839c01f16 169 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 117 132 5.2E-9 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L08_01190 27438dbfe01823ed529733d839c01f16 169 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 70 85 5.2E-9 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L08_01190 27438dbfe01823ed529733d839c01f16 169 SMART SM00418 68 148 5.5E-18 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L08_01190 27438dbfe01823ed529733d839c01f16 169 SUPERFAMILY SSF46785 4 59 3.71E-10 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L08_01190 27438dbfe01823ed529733d839c01f16 169 SMART SM00419 82 131 9.7E-4 T 23-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 A3L08_01190 27438dbfe01823ed529733d839c01f16 169 SUPERFAMILY SSF46785 65 157 5.56E-23 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L08_01190 27438dbfe01823ed529733d839c01f16 169 Pfam PF13412 Winged helix-turn-helix DNA-binding 6 46 4.4E-6 T 23-10-2018 A3L08_01190 27438dbfe01823ed529733d839c01f16 169 Pfam PF01022 Bacterial regulatory protein, arsR family 76 120 5.8E-13 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L08_01190 27438dbfe01823ed529733d839c01f16 169 Gene3D G3DSA:1.10.10.10 1 62 1.2E-14 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L08_05990 700fafcea3373fd1491ab2e5cd1f98b4 113 Gene3D G3DSA:1.10.10.1220 1 90 1.8E-41 T 23-10-2018 A3L08_07490 c0a07910cff3ffb07d949a42b5dfefe9 205 TIGRFAM TIGR00257 IMPACT_YIGZ: uncharacterized protein, YigZ family 5 198 6.3E-53 T 23-10-2018 IPR015796 Impact family, bacterial/archaeal A3L08_07490 c0a07910cff3ffb07d949a42b5dfefe9 205 Gene3D G3DSA:3.30.230.30 2 130 5.1E-47 T 23-10-2018 IPR036956 Impact, N-terminal domain superfamily A3L08_07490 c0a07910cff3ffb07d949a42b5dfefe9 205 ProSitePatterns PS00910 Uncharacterized protein family UPF0029 signature. 78 107 - T 23-10-2018 IPR020569 Uncharacterised protein family UPF0029, Impact, conserved site A3L08_07490 c0a07910cff3ffb07d949a42b5dfefe9 205 Pfam PF01205 Uncharacterized protein family UPF0029 17 123 1.3E-32 T 23-10-2018 IPR001498 Impact, N-terminal A3L08_07490 c0a07910cff3ffb07d949a42b5dfefe9 205 SUPERFAMILY SSF54980 136 198 1.37E-10 T 23-10-2018 IPR035647 EF-G domain III/V-like A3L08_07490 c0a07910cff3ffb07d949a42b5dfefe9 205 Pfam PF09186 Domain of unknown function (DUF1949) 139 194 5.5E-14 T 23-10-2018 IPR015269 Uncharacterised domain UPF0029, Impact, C-terminal A3L08_07490 c0a07910cff3ffb07d949a42b5dfefe9 205 SUPERFAMILY SSF54211 3 130 8.34E-42 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A3L08_04815 7a691fcb814bf7912e8ac3d453cacc26 163 SUPERFAMILY SSF46906 66 138 6.67E-23 T 23-10-2018 IPR036769 Ribosomal protein L11, C-terminal domain superfamily A3L08_04815 7a691fcb814bf7912e8ac3d453cacc26 163 Gene3D G3DSA:2.10.260.30 1 69 1.7E-28 T 23-10-2018 A3L08_04815 7a691fcb814bf7912e8ac3d453cacc26 163 ProSitePatterns PS00359 Ribosomal protein L11 signature. 124 139 - T 23-10-2018 IPR020785 Ribosomal protein L11, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_04815 7a691fcb814bf7912e8ac3d453cacc26 163 Pfam PF00298 Ribosomal protein L11, RNA binding domain 70 137 8.9E-23 T 23-10-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 A3L08_04815 7a691fcb814bf7912e8ac3d453cacc26 163 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 1 139 28.66 T 23-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 A3L08_04815 7a691fcb814bf7912e8ac3d453cacc26 163 Gene3D G3DSA:1.10.10.250 73 163 1.2E-35 T 23-10-2018 IPR036769 Ribosomal protein L11, C-terminal domain superfamily A3L08_04815 7a691fcb814bf7912e8ac3d453cacc26 163 SMART SM00649 5 138 4.9E-65 T 23-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 A3L08_04815 7a691fcb814bf7912e8ac3d453cacc26 163 SUPERFAMILY SSF54747 3 82 2.75E-26 T 23-10-2018 IPR036796 Ribosomal protein L11/L12, N-terminal domain superfamily A3L08_04815 7a691fcb814bf7912e8ac3d453cacc26 163 Pfam PF03946 Ribosomal protein L11, N-terminal domain 5 58 6.0E-23 T 23-10-2018 IPR020784 Ribosomal protein L11, N-terminal A3L08_01995 63f18cc7ecd39c481ff46405420b022e 226 Pfam PF05690 Thiazole biosynthesis protein ThiG 165 216 4.5E-6 T 23-10-2018 IPR033983 Thiazole synthase ThiG KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 A3L08_01995 63f18cc7ecd39c481ff46405420b022e 226 ProSitePatterns PS00171 Triosephosphate isomerase active site. 142 152 - T 23-10-2018 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L08_01995 63f18cc7ecd39c481ff46405420b022e 226 Gene3D G3DSA:3.20.20.70 1 225 1.2E-94 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L08_01995 63f18cc7ecd39c481ff46405420b022e 226 Hamap MF_00147_A Triosephosphate isomerase [tpiA]. 6 225 43.758 T 23-10-2018 IPR022891 Triosephosphate isomerase, archaeal GO:0004807|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003 A3L08_01995 63f18cc7ecd39c481ff46405420b022e 226 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 8 212 2.9E-63 T 23-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L08_01995 63f18cc7ecd39c481ff46405420b022e 226 SUPERFAMILY SSF51351 4 221 3.67E-47 T 23-10-2018 IPR035990 Triosephosphate isomerase superfamily GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L08_01995 63f18cc7ecd39c481ff46405420b022e 226 Pfam PF00121 Triosephosphate isomerase 8 115 5.0E-11 T 23-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A3L08_06805 9d930450f069f9ec75728a10c2b5cf36 264 Pfam PF01975 Survival protein SurE 3 192 2.0E-54 T 23-10-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 A3L08_06805 9d930450f069f9ec75728a10c2b5cf36 264 SUPERFAMILY SSF64167 1 253 6.54E-73 T 23-10-2018 A3L08_06805 9d930450f069f9ec75728a10c2b5cf36 264 Hamap MF_00060 5'/3'-nucleotidase SurE [surE]. 1 260 33.901 T 23-10-2018 IPR030048 Survival protein SurE GO:0008252 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 A3L08_06805 9d930450f069f9ec75728a10c2b5cf36 264 Gene3D G3DSA:3.40.1210.10 1 261 2.3E-86 T 23-10-2018 IPR036523 SurE-like phosphatase/nucleotidase superfamily GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 A3L08_06805 9d930450f069f9ec75728a10c2b5cf36 264 TIGRFAM TIGR00087 surE: 5'/3'-nucleotidase SurE 1 243 1.9E-72 T 23-10-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 A3L08_04380 743e37c499fe92b9289d7823ec8873cd 291 TIGRFAM TIGR04336 AmmeMemoSam_B: AmmeMemoRadiSam system protein B 3 288 1.3E-89 T 23-10-2018 A3L08_04380 743e37c499fe92b9289d7823ec8873cd 291 Gene3D G3DSA:3.40.830.10 1 291 4.8E-69 T 23-10-2018 A3L08_04380 743e37c499fe92b9289d7823ec8873cd 291 Pfam PF01875 Memo-like protein 5 288 5.5E-73 T 23-10-2018 IPR002737 MEMO1 family Reactome: R-HSA-6785631 A3L08_04380 743e37c499fe92b9289d7823ec8873cd 291 Hamap MF_00055 MEMO1 family protein . 1 290 61.072 T 23-10-2018 IPR002737 MEMO1 family Reactome: R-HSA-6785631 A3L08_04380 743e37c499fe92b9289d7823ec8873cd 291 SUPERFAMILY SSF53213 57 248 3.66E-8 T 23-10-2018 A3L08_00095 f1b0a851dd75430205d7869881dee50f 303 Pfam PF08271 TFIIB zinc-binding 6 47 2.6E-20 T 23-10-2018 IPR013137 Zinc finger, TFIIB-type A3L08_00095 f1b0a851dd75430205d7869881dee50f 303 Gene3D G3DSA:1.10.472.170 6 202 2.1E-68 T 23-10-2018 A3L08_00095 f1b0a851dd75430205d7869881dee50f 303 Gene3D G3DSA:1.10.472.10 211 303 8.6E-27 T 23-10-2018 A3L08_00095 f1b0a851dd75430205d7869881dee50f 303 Hamap MF_00383 Transcription initiation factor IIB [tfb]. 1 301 46.485 T 23-10-2018 IPR023484 Transcription initiation factor TFIIB, archaea A3L08_00095 f1b0a851dd75430205d7869881dee50f 303 SUPERFAMILY SSF47954 211 302 3.4E-29 T 23-10-2018 IPR036915 Cyclin-like superfamily A3L08_00095 f1b0a851dd75430205d7869881dee50f 303 PRINTS PR00685 Transcription initiation factor IIB signature 281 295 1.1E-58 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 A3L08_00095 f1b0a851dd75430205d7869881dee50f 303 PRINTS PR00685 Transcription initiation factor IIB signature 215 233 1.1E-58 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 A3L08_00095 f1b0a851dd75430205d7869881dee50f 303 PRINTS PR00685 Transcription initiation factor IIB signature 41 54 1.1E-58 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 A3L08_00095 f1b0a851dd75430205d7869881dee50f 303 PRINTS PR00685 Transcription initiation factor IIB signature 162 181 1.1E-58 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 A3L08_00095 f1b0a851dd75430205d7869881dee50f 303 PRINTS PR00685 Transcription initiation factor IIB signature 19 39 1.1E-58 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 A3L08_00095 f1b0a851dd75430205d7869881dee50f 303 PRINTS PR00685 Transcription initiation factor IIB signature 54 75 1.1E-58 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 A3L08_00095 f1b0a851dd75430205d7869881dee50f 303 PRINTS PR00685 Transcription initiation factor IIB signature 188 203 1.1E-58 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 A3L08_00095 f1b0a851dd75430205d7869881dee50f 303 PRINTS PR00685 Transcription initiation factor IIB signature 249 265 1.1E-58 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 A3L08_00095 f1b0a851dd75430205d7869881dee50f 303 SUPERFAMILY SSF57783 4 50 1.36E-18 T 23-10-2018 A3L08_00095 f1b0a851dd75430205d7869881dee50f 303 SMART SM00385 214 295 1.5E-10 T 23-10-2018 IPR013763 Cyclin-like A3L08_00095 f1b0a851dd75430205d7869881dee50f 303 SMART SM00385 120 201 9.9E-13 T 23-10-2018 IPR013763 Cyclin-like A3L08_00095 f1b0a851dd75430205d7869881dee50f 303 Pfam PF00382 Transcription factor TFIIB repeat 216 286 1.2E-19 T 23-10-2018 IPR013150 Transcription factor TFIIB, cyclin-like domain GO:0017025 A3L08_00095 f1b0a851dd75430205d7869881dee50f 303 Pfam PF00382 Transcription factor TFIIB repeat 123 192 5.0E-20 T 23-10-2018 IPR013150 Transcription factor TFIIB, cyclin-like domain GO:0017025 A3L08_00095 f1b0a851dd75430205d7869881dee50f 303 ProSitePatterns PS00782 Transcription factor TFIIB repeat signature. 154 169 - T 23-10-2018 IPR023486 Transcription factor TFIIB, conserved site Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-674695|Reactome: R-HSA-6807505|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-76042 A3L08_00095 f1b0a851dd75430205d7869881dee50f 303 SUPERFAMILY SSF47954 114 207 7.42E-26 T 23-10-2018 IPR036915 Cyclin-like superfamily A3L08_00095 f1b0a851dd75430205d7869881dee50f 303 ProSitePatterns PS00782 Transcription factor TFIIB repeat signature. 248 263 - T 23-10-2018 IPR023486 Transcription factor TFIIB, conserved site Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-674695|Reactome: R-HSA-6807505|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-76042 A3L08_06590 5e8fd4698107caec34d1c5501ed71cb8 168 SUPERFAMILY SSF54862 5 149 1.74E-48 T 23-10-2018 A3L08_06590 5e8fd4698107caec34d1c5501ed71cb8 168 Pfam PF13247 4Fe-4S dicluster domain 44 135 9.4E-26 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L08_06590 5e8fd4698107caec34d1c5501ed71cb8 168 PRINTS PR00354 7Fe ferredoxin signature 48 58 1.0E-5 T 23-10-2018 IPR000813 7Fe ferredoxin GO:0009055 A3L08_06590 5e8fd4698107caec34d1c5501ed71cb8 168 PRINTS PR00354 7Fe ferredoxin signature 75 92 1.0E-5 T 23-10-2018 IPR000813 7Fe ferredoxin GO:0009055 A3L08_06590 5e8fd4698107caec34d1c5501ed71cb8 168 PRINTS PR00354 7Fe ferredoxin signature 58 68 1.0E-5 T 23-10-2018 IPR000813 7Fe ferredoxin GO:0009055 A3L08_06590 5e8fd4698107caec34d1c5501ed71cb8 168 Gene3D G3DSA:3.30.70.20 28 161 3.5E-39 T 23-10-2018 A3L08_06590 5e8fd4698107caec34d1c5501ed71cb8 168 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 80 91 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L08_07215 abeeaa1a749f9846175bc24a148e0a5a 348 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 280 292 - T 23-10-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site A3L08_07215 abeeaa1a749f9846175bc24a148e0a5a 348 SUPERFAMILY SSF55920 123 347 1.31E-84 T 23-10-2018 IPR036005 Creatinase/aminopeptidase-like A3L08_07215 abeeaa1a749f9846175bc24a148e0a5a 348 Gene3D G3DSA:3.90.230.10 123 348 9.6E-90 T 23-10-2018 A3L08_07215 abeeaa1a749f9846175bc24a148e0a5a 348 Gene3D G3DSA:3.40.350.10 1 122 2.9E-30 T 23-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal A3L08_07215 abeeaa1a749f9846175bc24a148e0a5a 348 Pfam PF01321 Creatinase/Prolidase N-terminal domain 2 124 2.2E-22 T 23-10-2018 IPR000587 Creatinase, N-terminal GO:0016787 A3L08_07215 abeeaa1a749f9846175bc24a148e0a5a 348 Pfam PF00557 Metallopeptidase family M24 133 334 2.7E-70 T 23-10-2018 IPR000994 Peptidase M24 A3L08_07215 abeeaa1a749f9846175bc24a148e0a5a 348 SUPERFAMILY SSF53092 6 124 2.09E-25 T 23-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal A3L08_08125 114868a1685d181133633b6ec2ee43de 173 Pfam PF00210 Ferritin-like domain 7 143 3.0E-47 T 23-10-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 A3L08_08125 114868a1685d181133633b6ec2ee43de 173 SUPERFAMILY SSF47240 1 160 6.2E-62 T 23-10-2018 IPR009078 Ferritin-like superfamily A3L08_08125 114868a1685d181133633b6ec2ee43de 173 Gene3D G3DSA:1.20.1260.10 1 173 2.2E-58 T 23-10-2018 IPR012347 Ferritin-like A3L08_08690 041f3fab2f1a6da01b1a4ca33f9434b1 523 Pfam PF13181 Tetratricopeptide repeat 387 411 0.13 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A3L08_08690 041f3fab2f1a6da01b1a4ca33f9434b1 523 SUPERFAMILY SSF48452 315 405 3.19E-10 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A3L08_08690 041f3fab2f1a6da01b1a4ca33f9434b1 523 Pfam PF13374 Tetratricopeptide repeat 349 375 0.0015 T 23-10-2018 A3L08_08690 041f3fab2f1a6da01b1a4ca33f9434b1 523 Gene3D G3DSA:1.25.40.10 231 472 4.2E-15 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A3L08_03755 608c5dab8e602d2d07063795f24a3c60 740 SUPERFAMILY SSF50249 225 296 8.19E-11 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L08_03755 608c5dab8e602d2d07063795f24a3c60 740 SMART SM00316 131 196 4.5E-14 T 23-10-2018 IPR022967 RNA-binding domain, S1 A3L08_03755 608c5dab8e602d2d07063795f24a3c60 740 Gene3D G3DSA:2.40.50.140 218 307 1.1E-7 T 23-10-2018 A3L08_03755 608c5dab8e602d2d07063795f24a3c60 740 SUPERFAMILY SSF50249 121 196 2.61E-12 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L08_03755 608c5dab8e602d2d07063795f24a3c60 740 SUPERFAMILY SSF64182 336 734 1.7E-42 T 23-10-2018 IPR038763 DHH phosphoesterase superfamily A3L08_03755 608c5dab8e602d2d07063795f24a3c60 740 Gene3D G3DSA:3.90.1640.30 333 539 2.6E-9 T 23-10-2018 A3L08_03755 608c5dab8e602d2d07063795f24a3c60 740 Pfam PF01336 OB-fold nucleic acid binding domain 227 297 5.2E-11 T 23-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 A3L08_03755 608c5dab8e602d2d07063795f24a3c60 740 Gene3D G3DSA:2.40.50.140 128 202 5.6E-14 T 23-10-2018 A3L08_03755 608c5dab8e602d2d07063795f24a3c60 740 Pfam PF00575 S1 RNA binding domain 130 193 1.6E-10 T 23-10-2018 IPR003029 S1 domain GO:0003676 A3L08_01665 e76109d1a8053d9ca9f4445c7deb7cf0 626 Gene3D G3DSA:2.120.10.30 25 137 5.8E-11 T 23-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like A3L08_01665 e76109d1a8053d9ca9f4445c7deb7cf0 626 SUPERFAMILY SSF53474 352 606 4.09E-57 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold A3L08_01665 e76109d1a8053d9ca9f4445c7deb7cf0 626 Gene3D G3DSA:3.40.50.1820 353 622 3.5E-82 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold A3L08_01665 e76109d1a8053d9ca9f4445c7deb7cf0 626 Pfam PF00326 Prolyl oligopeptidase family 396 607 1.0E-52 T 23-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 A3L08_01665 e76109d1a8053d9ca9f4445c7deb7cf0 626 SUPERFAMILY SSF82171 26 340 1.57E-22 T 23-10-2018 A3L08_08985 ae4ed90217170015fc02dba2f85d2143 354 Gene3D G3DSA:2.40.50.100 238 344 2.4E-7 T 23-10-2018 A3L08_08985 ae4ed90217170015fc02dba2f85d2143 354 Gene3D G3DSA:3.40.50.300 1 237 1.9E-79 T 23-10-2018 A3L08_08985 ae4ed90217170015fc02dba2f85d2143 354 SUPERFAMILY SSF50331 237 349 5.44E-14 T 23-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal A3L08_08985 ae4ed90217170015fc02dba2f85d2143 354 TIGRFAM TIGR01187 potA: polyamine ABC transporter, ATP-binding protein 34 324 1.5E-109 T 23-10-2018 IPR005893 Spermidine/putrescine ABC transporter, ATP-binding subunit GO:0015417|GO:0015846|GO:0043190 A3L08_08985 ae4ed90217170015fc02dba2f85d2143 354 SMART SM00382 28 211 6.0E-16 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L08_08985 ae4ed90217170015fc02dba2f85d2143 354 Gene3D G3DSA:2.40.50.140 289 340 2.4E-7 T 23-10-2018 A3L08_08985 ae4ed90217170015fc02dba2f85d2143 354 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L08_08985 ae4ed90217170015fc02dba2f85d2143 354 Pfam PF08402 TOBE domain 275 349 4.4E-7 T 23-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 A3L08_08985 ae4ed90217170015fc02dba2f85d2143 354 Pfam PF00005 ABC transporter 19 161 1.5E-34 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L08_08985 ae4ed90217170015fc02dba2f85d2143 354 SUPERFAMILY SSF52540 4 244 1.64E-89 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_01465 052f58d6d2a477f0e3903ba1c93d45c4 375 ProDom PD014260 DIHYDROOROTATE DEHYDROGENASE THERMOPHILE-SPECIFIC TA1428 ST0318 BLL2851 16-BISPHOSPHATASE APE1109 PF0613 MJ0299 6 371 0.0 T 23-10-2018 IPR002803 Fructose-1,6-bisphosphatase, class V KEGG: 00010+4.1.2.13+3.1.3.11|KEGG: 00030+4.1.2.13+3.1.3.11|KEGG: 00051+4.1.2.13+3.1.3.11|KEGG: 00680+4.1.2.13+3.1.3.11|KEGG: 00710+4.1.2.13+3.1.3.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 A3L08_01465 052f58d6d2a477f0e3903ba1c93d45c4 375 PIRSF PIRSF015647 5 375 3.2E-191 T 23-10-2018 IPR002803 Fructose-1,6-bisphosphatase, class V KEGG: 00010+4.1.2.13+3.1.3.11|KEGG: 00030+4.1.2.13+3.1.3.11|KEGG: 00051+4.1.2.13+3.1.3.11|KEGG: 00680+4.1.2.13+3.1.3.11|KEGG: 00710+4.1.2.13+3.1.3.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 A3L08_01465 052f58d6d2a477f0e3903ba1c93d45c4 375 SUPERFAMILY SSF111249 6 372 1.31E-177 T 23-10-2018 IPR036076 Fructose-1,6-bisphosphatase, class V superfamily KEGG: 00010+3.1.3.11+4.1.2.13|KEGG: 00030+3.1.3.11+4.1.2.13|KEGG: 00051+3.1.3.11+4.1.2.13|KEGG: 00680+3.1.3.11+4.1.2.13|KEGG: 00710+3.1.3.11+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 A3L08_01465 052f58d6d2a477f0e3903ba1c93d45c4 375 Hamap MF_02067 Fructose-1,6-bisphosphate aldolase/phosphatase [fbp]. 5 372 61.875 T 23-10-2018 IPR002803 Fructose-1,6-bisphosphatase, class V KEGG: 00010+4.1.2.13+3.1.3.11|KEGG: 00030+4.1.2.13+3.1.3.11|KEGG: 00051+4.1.2.13+3.1.3.11|KEGG: 00680+4.1.2.13+3.1.3.11|KEGG: 00710+4.1.2.13+3.1.3.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 A3L08_01465 052f58d6d2a477f0e3903ba1c93d45c4 375 Pfam PF01950 Fructose-1,6-bisphosphatase 6 372 4.3E-186 T 23-10-2018 IPR002803 Fructose-1,6-bisphosphatase, class V KEGG: 00010+4.1.2.13+3.1.3.11|KEGG: 00030+4.1.2.13+3.1.3.11|KEGG: 00051+4.1.2.13+3.1.3.11|KEGG: 00680+4.1.2.13+3.1.3.11|KEGG: 00710+4.1.2.13+3.1.3.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 A3L08_07330 01cf96ce19dea39c47b20ae0d2897f96 244 Gene3D G3DSA:3.30.1370.10 35 117 2.7E-34 T 23-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 A3L08_07330 01cf96ce19dea39c47b20ae0d2897f96 244 Pfam PF00013 KH domain 142 189 3.7E-6 T 23-10-2018 IPR004088 K Homology domain, type 1 GO:0003723 A3L08_07330 01cf96ce19dea39c47b20ae0d2897f96 244 Pfam PF00013 KH domain 40 86 3.3E-9 T 23-10-2018 IPR004088 K Homology domain, type 1 GO:0003723 A3L08_07330 01cf96ce19dea39c47b20ae0d2897f96 244 TIGRFAM TIGR03665 arCOG04150: arCOG04150 universal archaeal KH domain protein 41 214 1.5E-68 T 23-10-2018 IPR019964 KH domain protein, archaea A3L08_07330 01cf96ce19dea39c47b20ae0d2897f96 244 SUPERFAMILY SSF54791 137 204 5.26E-18 T 23-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 A3L08_07330 01cf96ce19dea39c47b20ae0d2897f96 244 SUPERFAMILY SSF54791 39 114 8.14E-13 T 23-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 A3L08_07330 01cf96ce19dea39c47b20ae0d2897f96 244 Gene3D G3DSA:3.30.1370.10 118 223 2.5E-32 T 23-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 A3L08_07330 01cf96ce19dea39c47b20ae0d2897f96 244 SMART SM00322 126 193 1.5E-7 T 23-10-2018 IPR004087 K Homology domain GO:0003676 A3L08_07330 01cf96ce19dea39c47b20ae0d2897f96 244 SMART SM00322 35 105 3.6E-10 T 23-10-2018 IPR004087 K Homology domain GO:0003676 A3L08_08780 b193042b1e17b13b0751dc86526bb784 422 SUPERFAMILY SSF53335 62 419 2.6E-66 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L08_08780 b193042b1e17b13b0751dc86526bb784 422 Gene3D G3DSA:3.40.1350.30 114 262 4.2E-95 T 23-10-2018 A3L08_08780 b193042b1e17b13b0751dc86526bb784 422 Gene3D G3DSA:3.40.50.150 75 414 4.2E-95 T 23-10-2018 A3L08_08780 b193042b1e17b13b0751dc86526bb784 422 Gene3D G3DSA:2.40.50.140 3 63 3.8E-16 T 23-10-2018 A3L08_08780 b193042b1e17b13b0751dc86526bb784 422 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 402 412 - T 23-10-2018 IPR030391 RNA methyltransferase TrmA, conserved site A3L08_08780 b193042b1e17b13b0751dc86526bb784 422 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 351 380 - T 23-10-2018 IPR030390 RNA methyltransferase TrmA, active site A3L08_08780 b193042b1e17b13b0751dc86526bb784 422 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 251 420 3.2E-19 T 23-10-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 A3L08_08780 b193042b1e17b13b0751dc86526bb784 422 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 13 412 8.0E-67 T 23-10-2018 A3L08_08780 b193042b1e17b13b0751dc86526bb784 422 SUPERFAMILY SSF50249 5 60 1.31E-5 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L08_05580 9ef05a61eec4947cba1992faf80e809c 196 Pfam PF10447 Exosome component EXOSC1/CSL4 66 122 8.6E-6 T 23-10-2018 IPR019495 Exosome complex component CSL4, C-terminal GO:0000178|GO:0003723 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A3L08_05580 9ef05a61eec4947cba1992faf80e809c 196 Gene3D G3DSA:2.40.50.140 65 155 2.0E-24 T 23-10-2018 A3L08_05580 9ef05a61eec4947cba1992faf80e809c 196 Pfam PF14382 Exosome complex exonuclease RRP4 N-terminal region 12 48 1.6E-6 T 23-10-2018 IPR025721 Exosome complex component, N-terminal domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A3L08_05580 9ef05a61eec4947cba1992faf80e809c 196 SMART SM00316 68 149 2.4E-10 T 23-10-2018 IPR022967 RNA-binding domain, S1 A3L08_05580 9ef05a61eec4947cba1992faf80e809c 196 Gene3D G3DSA:2.20.70.10 156 189 5.7E-17 T 23-10-2018 A3L08_05580 9ef05a61eec4947cba1992faf80e809c 196 Hamap MF_00975 Exosome complex component Csl4 [csl4]. 12 193 28.801 T 23-10-2018 IPR030850 Exosome complex component Csl4, archaea GO:0000178|GO:0006396 A3L08_05580 9ef05a61eec4947cba1992faf80e809c 196 SUPERFAMILY SSF50249 64 186 9.8E-30 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L08_05580 9ef05a61eec4947cba1992faf80e809c 196 SUPERFAMILY SSF110324 11 63 3.98E-12 T 23-10-2018 A3L08_05580 9ef05a61eec4947cba1992faf80e809c 196 Gene3D G3DSA:2.40.50.100 11 61 9.1E-16 T 23-10-2018 A3L08_06535 3bcede2cfa3f4ad0f1d844cc2b2fa47b 253 Gene3D G3DSA:3.40.50.12280 1 162 1.3E-45 T 23-10-2018 A3L08_06535 3bcede2cfa3f4ad0f1d844cc2b2fa47b 253 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 14 136 2.0E-25 T 23-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L08_06535 3bcede2cfa3f4ad0f1d844cc2b2fa47b 253 SUPERFAMILY SSF56770 2 150 1.57E-46 T 23-10-2018 A3L08_05230 655b6b03301390b2e16b77f4520fd49b 136 SUPERFAMILY SSF82784 3 124 4.84E-28 T 23-10-2018 IPR036102 OsmC/Ohr superfamily A3L08_05230 655b6b03301390b2e16b77f4520fd49b 136 Gene3D G3DSA:3.30.300.20 1 122 3.6E-25 T 23-10-2018 IPR015946 K homology domain-like, alpha/beta A3L08_05230 655b6b03301390b2e16b77f4520fd49b 136 Pfam PF02566 OsmC-like protein 35 128 2.2E-18 T 23-10-2018 IPR003718 OsmC/Ohr family A3L08_00660 2ec318d0ae4482e55dc4b30227bdeeca 439 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 229 243 4.5E-17 T 23-10-2018 A3L08_00660 2ec318d0ae4482e55dc4b30227bdeeca 439 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 268 275 4.5E-17 T 23-10-2018 A3L08_00660 2ec318d0ae4482e55dc4b30227bdeeca 439 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 2 24 4.5E-17 T 23-10-2018 A3L08_00660 2ec318d0ae4482e55dc4b30227bdeeca 439 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 145 170 4.5E-17 T 23-10-2018 A3L08_00660 2ec318d0ae4482e55dc4b30227bdeeca 439 SUPERFAMILY SSF55424 316 437 8.08E-28 T 23-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 A3L08_00660 2ec318d0ae4482e55dc4b30227bdeeca 439 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 228 244 2.2E-22 T 23-10-2018 A3L08_00660 2ec318d0ae4482e55dc4b30227bdeeca 439 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 3 22 2.2E-22 T 23-10-2018 A3L08_00660 2ec318d0ae4482e55dc4b30227bdeeca 439 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 98 116 2.2E-22 T 23-10-2018 A3L08_00660 2ec318d0ae4482e55dc4b30227bdeeca 439 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 145 163 2.2E-22 T 23-10-2018 A3L08_00660 2ec318d0ae4482e55dc4b30227bdeeca 439 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 253 275 2.2E-22 T 23-10-2018 A3L08_00660 2ec318d0ae4482e55dc4b30227bdeeca 439 Gene3D G3DSA:3.50.50.60 2 331 9.4E-149 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L08_00660 2ec318d0ae4482e55dc4b30227bdeeca 439 Gene3D G3DSA:3.50.50.60 107 431 9.4E-149 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L08_00660 2ec318d0ae4482e55dc4b30227bdeeca 439 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 324 423 5.5E-17 T 23-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 A3L08_00660 2ec318d0ae4482e55dc4b30227bdeeca 439 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 295 1.1E-69 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A3L08_00660 2ec318d0ae4482e55dc4b30227bdeeca 439 SUPERFAMILY SSF51905 142 307 6.22E-35 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L08_00660 2ec318d0ae4482e55dc4b30227bdeeca 439 SUPERFAMILY SSF51905 1 191 2.81E-48 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L08_00930 99ad47b2a43e59071704eaa241192fd7 279 Gene3D G3DSA:3.40.50.2020 16 138 6.2E-82 T 23-10-2018 A3L08_00930 99ad47b2a43e59071704eaa241192fd7 279 Gene3D G3DSA:3.40.50.2020 139 263 6.2E-82 T 23-10-2018 A3L08_00930 99ad47b2a43e59071704eaa241192fd7 279 SMART SM01400 1 113 8.6E-33 T 23-10-2018 A3L08_00930 99ad47b2a43e59071704eaa241192fd7 279 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 5 110 7.1E-20 T 23-10-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 A3L08_00930 99ad47b2a43e59071704eaa241192fd7 279 SUPERFAMILY SSF53271 80 263 3.45E-37 T 23-10-2018 IPR029057 Phosphoribosyltransferase-like A3L08_00930 99ad47b2a43e59071704eaa241192fd7 279 Hamap MF_00583_A Putative ribose-phosphate pyrophosphokinase [prs]. 1 278 36.532 T 23-10-2018 IPR037514 Ribose-phosphate pyrophosphokinase, archaea GO:0004749 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 A3L08_00930 99ad47b2a43e59071704eaa241192fd7 279 Pfam PF00156 Phosphoribosyl transferase domain 141 239 1.4E-16 T 23-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 A3L08_00930 99ad47b2a43e59071704eaa241192fd7 279 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 2 274 2.2E-89 T 23-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 A3L08_04410 0c2d2d977f8cda3d3576891a545ae0ae 453 SUPERFAMILY SSF52540 235 453 7.09E-48 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_04410 0c2d2d977f8cda3d3576891a545ae0ae 453 SUPERFAMILY SSF52540 5 222 2.9E-32 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_04410 0c2d2d977f8cda3d3576891a545ae0ae 453 Pfam PF06745 KaiC 238 453 5.2E-43 T 23-10-2018 IPR014774 KaiC-like domain A3L08_04410 0c2d2d977f8cda3d3576891a545ae0ae 453 Pfam PF06745 KaiC 3 222 1.5E-60 T 23-10-2018 IPR014774 KaiC-like domain A3L08_04410 0c2d2d977f8cda3d3576891a545ae0ae 453 Gene3D G3DSA:3.40.50.300 230 453 9.1E-59 T 23-10-2018 A3L08_04410 0c2d2d977f8cda3d3576891a545ae0ae 453 Gene3D G3DSA:3.40.50.300 3 225 1.0E-48 T 23-10-2018 A3L08_04410 0c2d2d977f8cda3d3576891a545ae0ae 453 PRINTS PR01874 DNA repair protein radA signature 289 306 2.6E-7 T 23-10-2018 A3L08_04410 0c2d2d977f8cda3d3576891a545ae0ae 453 PRINTS PR01874 DNA repair protein radA signature 247 275 2.6E-7 T 23-10-2018 A3L08_04410 0c2d2d977f8cda3d3576891a545ae0ae 453 SMART SM00382 20 185 4.0 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L08_04410 0c2d2d977f8cda3d3576891a545ae0ae 453 SMART SM00382 255 415 5.9E-5 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L08_04410 0c2d2d977f8cda3d3576891a545ae0ae 453 PIRSF PIRSF039117 2 453 9.2E-118 T 23-10-2018 IPR030665 Circadian clock protein kinase KaiC KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1 A3L08_00985 93741b90d328027a85378f842141917b 395 Gene3D G3DSA:3.90.1150.10 35 385 1.3E-138 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A3L08_00985 93741b90d328027a85378f842141917b 395 Pfam PF00155 Aminotransferase class I and II 39 383 1.3E-69 T 23-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A3L08_00985 93741b90d328027a85378f842141917b 395 Gene3D G3DSA:3.40.640.10 55 291 1.3E-138 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A3L08_00985 93741b90d328027a85378f842141917b 395 SUPERFAMILY SSF53383 4 391 7.71E-118 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A3L08_00985 93741b90d328027a85378f842141917b 395 TIGRFAM TIGR01825 gly_Cac_T_rel: putative pyridoxal phosphate-dependent acyltransferase 7 394 2.2E-199 T 23-10-2018 IPR010962 Putative 8-amino-7-oxononanoate synthase, Archaea/Firmicutes type A3L08_00985 93741b90d328027a85378f842141917b 395 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 238 247 - T 23-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 A3L08_00530 e4d4807e38d10457c47042d82507ba91 350 Gene3D G3DSA:3.40.47.10 8 348 6.1E-68 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 A3L08_00530 e4d4807e38d10457c47042d82507ba91 350 Hamap MF_01409 UPF0219 protein . 10 350 60.062 T 23-10-2018 IPR004656 Putative condensing enzyme FabH-related A3L08_00530 e4d4807e38d10457c47042d82507ba91 350 TIGRFAM TIGR00748 HMG_CoA_syn_Arc: putative hydroxymethylglutaryl-CoA synthase 11 350 2.9E-187 T 23-10-2018 IPR004656 Putative condensing enzyme FabH-related A3L08_00530 e4d4807e38d10457c47042d82507ba91 350 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 224 303 1.0E-9 T 23-10-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 A3L08_00530 e4d4807e38d10457c47042d82507ba91 350 SUPERFAMILY SSF53901 11 169 1.91E-30 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 A3L08_00530 e4d4807e38d10457c47042d82507ba91 350 SUPERFAMILY SSF53901 174 348 4.45E-45 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 A3L08_08215 587ebdd6c769dd396eb575683972aca0 338 SUPERFAMILY SSF159071 247 326 1.22E-11 T 23-10-2018 A3L08_08215 587ebdd6c769dd396eb575683972aca0 338 SUPERFAMILY SSF56024 108 235 6.91E-22 T 23-10-2018 A3L08_08215 587ebdd6c769dd396eb575683972aca0 338 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 8 75 4.4E-20 T 23-10-2018 IPR002831 Transcription regulator TrmB, N-terminal A3L08_08215 587ebdd6c769dd396eb575683972aca0 338 Gene3D G3DSA:1.10.10.10 1 99 7.6E-24 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L08_08215 587ebdd6c769dd396eb575683972aca0 338 Gene3D G3DSA:3.30.870.10 107 242 1.5E-57 T 23-10-2018 A3L08_08215 587ebdd6c769dd396eb575683972aca0 338 Pfam PF11495 Archaeal transcriptional regulator TrmB 108 326 7.9E-23 T 23-10-2018 IPR021586 Transcription regulator TrmB, C-terminal A3L08_08215 587ebdd6c769dd396eb575683972aca0 338 SUPERFAMILY SSF46785 3 93 5.15E-7 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L08_05745 cc2a98dac9470d6cad8ea97222f887ea 581 SUPERFAMILY SSF102114 196 444 7.72E-26 T 23-10-2018 A3L08_05745 cc2a98dac9470d6cad8ea97222f887ea 581 SMART SM00729 200 447 1.0E-29 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A3L08_05745 cc2a98dac9470d6cad8ea97222f887ea 581 SUPERFAMILY SSF81585 511 573 1.57E-8 T 23-10-2018 A3L08_05745 cc2a98dac9470d6cad8ea97222f887ea 581 Pfam PF04055 Radical SAM superfamily 204 402 7.1E-25 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L08_05745 cc2a98dac9470d6cad8ea97222f887ea 581 Gene3D G3DSA:3.80.30.20 200 457 1.0E-24 T 23-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe A3L08_05745 cc2a98dac9470d6cad8ea97222f887ea 581 Gene3D G3DSA:1.10.150.320 519 576 3.1E-6 T 23-10-2018 A3L08_00865 d3b19b314a1c1b1182d85f61c1650c1b 306 Pfam PF01112 Asparaginase 3 298 9.9E-93 T 23-10-2018 IPR000246 Peptidase T2, asparaginase 2 GO:0016787 A3L08_00865 d3b19b314a1c1b1182d85f61c1650c1b 306 SUPERFAMILY SSF56235 18 299 2.11E-86 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A3L08_00865 d3b19b314a1c1b1182d85f61c1650c1b 306 Gene3D G3DSA:3.60.20.30 176 303 2.9E-32 T 23-10-2018 A3L08_08775 639a0b420eb677c63fac9ad36f36b977 404 Pfam PF00155 Aminotransferase class I and II 35 396 9.3E-44 T 23-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A3L08_08775 639a0b420eb677c63fac9ad36f36b977 404 SUPERFAMILY SSF53383 3 402 2.99E-106 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A3L08_08775 639a0b420eb677c63fac9ad36f36b977 404 Gene3D G3DSA:3.90.1150.10 22 397 2.1E-142 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A3L08_08775 639a0b420eb677c63fac9ad36f36b977 404 Gene3D G3DSA:3.40.640.10 70 294 2.1E-142 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A3L08_08800 c81d08b1aad4bfdf7675d110a452d26c 174 SUPERFAMILY SSF54919 6 152 1.7E-60 T 23-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A3L08_08800 c81d08b1aad4bfdf7675d110a452d26c 174 SMART SM00562 6 146 2.7E-82 T 23-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A3L08_08800 c81d08b1aad4bfdf7675d110a452d26c 174 Pfam PF00334 Nucleoside diphosphate kinase 7 143 5.1E-57 T 23-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A3L08_08800 c81d08b1aad4bfdf7675d110a452d26c 174 ProSitePatterns PS00469 Nucleoside diphosphate kinases active site. 120 128 - T 23-10-2018 IPR023005 Nucleoside diphosphate kinase, active site KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A3L08_08800 c81d08b1aad4bfdf7675d110a452d26c 174 PRINTS PR01243 Nucleoside diphosphate kinase signature 73 90 1.8E-42 T 23-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A3L08_08800 c81d08b1aad4bfdf7675d110a452d26c 174 PRINTS PR01243 Nucleoside diphosphate kinase signature 94 110 1.8E-42 T 23-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A3L08_08800 c81d08b1aad4bfdf7675d110a452d26c 174 PRINTS PR01243 Nucleoside diphosphate kinase signature 120 139 1.8E-42 T 23-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A3L08_08800 c81d08b1aad4bfdf7675d110a452d26c 174 PRINTS PR01243 Nucleoside diphosphate kinase signature 9 31 1.8E-42 T 23-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A3L08_08800 c81d08b1aad4bfdf7675d110a452d26c 174 PRINTS PR01243 Nucleoside diphosphate kinase signature 53 72 1.8E-42 T 23-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A3L08_08800 c81d08b1aad4bfdf7675d110a452d26c 174 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 6 144 35.998 T 23-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A3L08_08800 c81d08b1aad4bfdf7675d110a452d26c 174 Gene3D G3DSA:3.30.70.141 1 159 1.3E-69 T 23-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A3L08_01030 f20cd10dc26591bbf53d4cfcca63bab9 261 Gene3D G3DSA:3.40.830.10 1 260 1.6E-72 T 23-10-2018 A3L08_01030 f20cd10dc26591bbf53d4cfcca63bab9 261 SUPERFAMILY SSF53213 4 258 6.41E-25 T 23-10-2018 A3L08_01030 f20cd10dc26591bbf53d4cfcca63bab9 261 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 5 252 9.5E-16 T 23-10-2018 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 A3L08_09690 0aca84dee4caf41d6a00f951581abdd6 190 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 6 64 2.3E-18 T 23-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 A3L08_09690 0aca84dee4caf41d6a00f951581abdd6 190 TIGRFAM TIGR01527 arch_NMN_Atrans: nicotinamide-nucleotide adenylyltransferase 6 171 1.1E-69 T 23-10-2018 IPR006418 Nicotinamide-nucleotide adenylyltransferase, archaeal type GO:0000309|GO:0005737|GO:0009435 KEGG: 00760+2.7.7.1 A3L08_09690 0aca84dee4caf41d6a00f951581abdd6 190 Pfam PF01467 Cytidylyltransferase-like 8 139 1.1E-18 T 23-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 A3L08_09690 0aca84dee4caf41d6a00f951581abdd6 190 SUPERFAMILY SSF52374 5 169 1.01E-36 T 23-10-2018 A3L08_09690 0aca84dee4caf41d6a00f951581abdd6 190 Hamap MF_00243 Nicotinamide-nucleotide adenylyltransferase. 1 190 90.956 T 23-10-2018 IPR006418 Nicotinamide-nucleotide adenylyltransferase, archaeal type GO:0000309|GO:0005737|GO:0009435 KEGG: 00760+2.7.7.1 A3L08_09690 0aca84dee4caf41d6a00f951581abdd6 190 Gene3D G3DSA:3.40.50.620 3 181 8.7E-55 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L08_02110 fa471a7eb10351f5d7623dcd12fddbd1 191 SUPERFAMILY SSF46785 1 166 1.74E-35 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L08_02110 fa471a7eb10351f5d7623dcd12fddbd1 191 Gene3D G3DSA:1.10.20.10 90 191 5.7E-50 T 23-10-2018 IPR009072 Histone-fold GO:0046982 A3L08_02110 fa471a7eb10351f5d7623dcd12fddbd1 191 Pfam PF12840 Helix-turn-helix domain 11 67 1.1E-15 T 23-10-2018 A3L08_02110 fa471a7eb10351f5d7623dcd12fddbd1 191 Gene3D G3DSA:1.10.10.10 1 89 1.3E-31 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L08_02110 fa471a7eb10351f5d7623dcd12fddbd1 191 SMART SM00418 11 105 8.4E-11 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L08_07780 b9e2bf297e3aca705c72c4870618efef 397 Pfam PF08438 GTPase of unknown function C-terminal 220 327 2.8E-35 T 23-10-2018 IPR013646 Uncharacterised GTP-binding protein, C-terminal A3L08_07780 b9e2bf297e3aca705c72c4870618efef 397 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 92 110 4.4E-31 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L08_07780 b9e2bf297e3aca705c72c4870618efef 397 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 3 23 4.4E-31 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L08_07780 b9e2bf297e3aca705c72c4870618efef 397 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 75 90 4.4E-31 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L08_07780 b9e2bf297e3aca705c72c4870618efef 397 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 24 42 4.4E-31 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L08_07780 b9e2bf297e3aca705c72c4870618efef 397 Gene3D G3DSA:1.10.8.470 126 215 7.0E-31 T 23-10-2018 A3L08_07780 b9e2bf297e3aca705c72c4870618efef 397 Pfam PF02824 TGS domain 341 393 6.4E-14 T 23-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 A3L08_07780 b9e2bf297e3aca705c72c4870618efef 397 Pfam PF01926 50S ribosome-binding GTPase 2 121 8.9E-20 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L08_07780 b9e2bf297e3aca705c72c4870618efef 397 SUPERFAMILY SSF81271 323 393 6.28E-19 T 23-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 A3L08_07780 b9e2bf297e3aca705c72c4870618efef 397 Gene3D G3DSA:3.10.20.30 319 397 2.0E-31 T 23-10-2018 IPR012675 Beta-grasp domain superfamily A3L08_07780 b9e2bf297e3aca705c72c4870618efef 397 SUPERFAMILY SSF52540 1 315 6.2E-70 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_06815 26a0a338183807bf1ef5f1c320fa58cc 330 Pfam PF00448 SRP54-type protein, GTPase domain 133 327 9.0E-80 T 23-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A3L08_06815 26a0a338183807bf1ef5f1c320fa58cc 330 SUPERFAMILY SSF52540 131 328 4.69E-56 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_06815 26a0a338183807bf1ef5f1c320fa58cc 330 Gene3D G3DSA:1.20.120.140 2 116 1.1E-23 T 23-10-2018 A3L08_06815 26a0a338183807bf1ef5f1c320fa58cc 330 Gene3D G3DSA:3.40.50.300 119 327 1.5E-85 T 23-10-2018 A3L08_06815 26a0a338183807bf1ef5f1c320fa58cc 330 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 53 328 59.248 T 23-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 A3L08_06815 26a0a338183807bf1ef5f1c320fa58cc 330 Pfam PF02881 SRP54-type protein, helical bundle domain 48 109 1.9E-12 T 23-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A3L08_06815 26a0a338183807bf1ef5f1c320fa58cc 330 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 301 314 - T 23-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A3L08_06815 26a0a338183807bf1ef5f1c320fa58cc 330 SMART SM00963 32 114 2.3E-12 T 23-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A3L08_06815 26a0a338183807bf1ef5f1c320fa58cc 330 SMART SM00962 133 328 2.7E-113 T 23-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A3L08_06815 26a0a338183807bf1ef5f1c320fa58cc 330 SUPERFAMILY SSF47364 48 118 3.14E-16 T 23-10-2018 IPR036225 SRP/SRP receptor, N-terminal Reactome: R-HSA-1799339 A3L08_06815 26a0a338183807bf1ef5f1c320fa58cc 330 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 54 327 3.7E-110 T 23-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 A3L08_06815 26a0a338183807bf1ef5f1c320fa58cc 330 SMART SM00382 132 327 1.1E-8 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L08_00270 ff34ea0c779829be1c2c078f097145bb 726 SUPERFAMILY SSF158702 493 701 8.37E-61 T 23-10-2018 A3L08_00270 ff34ea0c779829be1c2c078f097145bb 726 SUPERFAMILY SSF52540 36 388 1.26E-47 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_00270 ff34ea0c779829be1c2c078f097145bb 726 Gene3D G3DSA:3.40.50.300 201 399 4.8E-63 T 23-10-2018 A3L08_00270 ff34ea0c779829be1c2c078f097145bb 726 SMART SM00490 288 374 8.0E-16 T 23-10-2018 IPR001650 Helicase, C-terminal A3L08_00270 ff34ea0c779829be1c2c078f097145bb 726 Pfam PF00270 DEAD/DEAH box helicase 26 180 6.2E-25 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A3L08_00270 ff34ea0c779829be1c2c078f097145bb 726 SMART SM00487 20 210 1.4E-30 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A3L08_00270 ff34ea0c779829be1c2c078f097145bb 726 SUPERFAMILY SSF46785 405 492 5.98E-16 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L08_00270 ff34ea0c779829be1c2c078f097145bb 726 Gene3D G3DSA:1.10.150.20 643 699 2.8E-22 T 23-10-2018 A3L08_00270 ff34ea0c779829be1c2c078f097145bb 726 Gene3D G3DSA:3.40.50.300 8 200 4.2E-74 T 23-10-2018 A3L08_00270 ff34ea0c779829be1c2c078f097145bb 726 Hamap MF_00442 ATP-dependent DNA helicase Hel308 [hel308]. 9 700 30.671 T 23-10-2018 IPR022965 ATP-dependent DNA helicase Hel308 GO:0004386 A3L08_00270 ff34ea0c779829be1c2c078f097145bb 726 Pfam PF00271 Helicase conserved C-terminal domain 233 373 1.4E-9 T 23-10-2018 IPR001650 Helicase, C-terminal A3L08_00270 ff34ea0c779829be1c2c078f097145bb 726 Gene3D G3DSA:1.10.3380.30 411 641 2.8E-73 T 23-10-2018 A3L08_00270 ff34ea0c779829be1c2c078f097145bb 726 Pfam PF14520 Helix-hairpin-helix domain 646 692 3.8E-11 T 23-10-2018 A3L08_00270 ff34ea0c779829be1c2c078f097145bb 726 SMART SM00278 678 697 0.52 T 23-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A3L08_00270 ff34ea0c779829be1c2c078f097145bb 726 SMART SM00278 645 664 0.59 T 23-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A3L08_05855 455e1d7ec3aa03de655c382358139f0f 315 SUPERFAMILY SSF53671 4 313 4.98E-116 T 23-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 A3L08_05855 455e1d7ec3aa03de655c382358139f0f 315 Gene3D G3DSA:3.40.50.1370 10 307 7.5E-138 T 23-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 A3L08_05855 455e1d7ec3aa03de655c382358139f0f 315 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 53 60 - T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A3L08_05855 455e1d7ec3aa03de655c382358139f0f 315 PRINTS PR00102 Ornithine carbamoyltransferase signature 124 138 1.8E-30 T 23-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 A3L08_05855 455e1d7ec3aa03de655c382358139f0f 315 PRINTS PR00102 Ornithine carbamoyltransferase signature 84 97 1.8E-30 T 23-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 A3L08_05855 455e1d7ec3aa03de655c382358139f0f 315 PRINTS PR00102 Ornithine carbamoyltransferase signature 227 237 1.8E-30 T 23-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 A3L08_05855 455e1d7ec3aa03de655c382358139f0f 315 PRINTS PR00102 Ornithine carbamoyltransferase signature 51 65 1.8E-30 T 23-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 A3L08_05855 455e1d7ec3aa03de655c382358139f0f 315 PRINTS PR00102 Ornithine carbamoyltransferase signature 289 300 1.8E-30 T 23-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 A3L08_05855 455e1d7ec3aa03de655c382358139f0f 315 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 8 148 6.6E-51 T 23-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 A3L08_05855 455e1d7ec3aa03de655c382358139f0f 315 Gene3D G3DSA:3.40.50.1370 138 297 7.5E-138 T 23-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 A3L08_05855 455e1d7ec3aa03de655c382358139f0f 315 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 8 310 3.8E-145 T 23-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 A3L08_05855 455e1d7ec3aa03de655c382358139f0f 315 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 7 311 85.425 T 23-10-2018 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 A3L08_05855 455e1d7ec3aa03de655c382358139f0f 315 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 275 298 2.2E-29 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A3L08_05855 455e1d7ec3aa03de655c382358139f0f 315 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 135 146 2.2E-29 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A3L08_05855 455e1d7ec3aa03de655c382358139f0f 315 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 53 72 2.2E-29 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A3L08_05855 455e1d7ec3aa03de655c382358139f0f 315 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 263 272 2.2E-29 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A3L08_05855 455e1d7ec3aa03de655c382358139f0f 315 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 155 308 1.1E-65 T 23-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 A3L08_08345 1ce57dbd28ebccb948a121480896ae5a 159 Gene3D G3DSA:1.20.1260.10 1 143 2.2E-26 T 23-10-2018 IPR012347 Ferritin-like A3L08_08345 1ce57dbd28ebccb948a121480896ae5a 159 Pfam PF02915 Rubrerythrin 5 138 1.0E-16 T 23-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 A3L08_08345 1ce57dbd28ebccb948a121480896ae5a 159 SUPERFAMILY SSF47240 1 147 1.24E-27 T 23-10-2018 IPR009078 Ferritin-like superfamily A3L08_02600 630b2189b7ff1d314df6fda74802ecf5 585 Gene3D G3DSA:1.10.1140.10 435 585 8.7E-60 T 23-10-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A3L08_02600 630b2189b7ff1d314df6fda74802ecf5 585 SUPERFAMILY SSF52540 163 440 1.55E-85 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_02600 630b2189b7ff1d314df6fda74802ecf5 585 SUPERFAMILY SSF50615 1 68 1.57E-13 T 23-10-2018 IPR036121 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A3L08_02600 630b2189b7ff1d314df6fda74802ecf5 585 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 211 434 8.4E-93 T 23-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A3L08_02600 630b2189b7ff1d314df6fda74802ecf5 585 SUPERFAMILY SSF47917 447 552 3.92E-27 T 23-10-2018 A3L08_02600 630b2189b7ff1d314df6fda74802ecf5 585 Gene3D G3DSA:2.40.50.100 113 184 4.3E-185 T 23-10-2018 A3L08_02600 630b2189b7ff1d314df6fda74802ecf5 585 TIGRFAM TIGR01043 ATP_syn_A_arch: ATP synthase archaeal, A subunit 1 580 0.0 T 23-10-2018 IPR005726 ATP synthase alpha chain, archaea GO:0015986|GO:0033178|GO:0046961 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A3L08_02600 630b2189b7ff1d314df6fda74802ecf5 585 Hamap MF_00309 V-type ATP synthase alpha chain [atpA]. 1 583 54.905 T 23-10-2018 IPR022878 V-type ATP synthase catalytic alpha chain GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A3L08_02600 630b2189b7ff1d314df6fda74802ecf5 585 Pfam PF16886 ATPsynthase alpha/beta subunit N-term extension 82 202 1.4E-47 T 23-10-2018 IPR031686 ATPsynthase alpha/beta subunit, N-terminal extension KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A3L08_02600 630b2189b7ff1d314df6fda74802ecf5 585 Gene3D G3DSA:2.40.30.20 1 69 8.7E-30 T 23-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A3L08_02600 630b2189b7ff1d314df6fda74802ecf5 585 SMART SM00382 223 411 0.0016 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L08_02600 630b2189b7ff1d314df6fda74802ecf5 585 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 4 66 9.0E-15 T 23-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A3L08_02600 630b2189b7ff1d314df6fda74802ecf5 585 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 425 434 - T 23-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A3L08_02600 630b2189b7ff1d314df6fda74802ecf5 585 Gene3D G3DSA:3.40.50.300 70 434 4.3E-185 T 23-10-2018 A3L08_03630 8c994a99f8c1a6bd4f60596ba8967a65 209 SUPERFAMILY SSF46785 3 81 1.82E-13 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L08_03630 8c994a99f8c1a6bd4f60596ba8967a65 209 SUPERFAMILY SSF46785 85 152 4.33E-15 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L08_03630 8c994a99f8c1a6bd4f60596ba8967a65 209 Gene3D G3DSA:1.10.10.10 83 163 1.7E-12 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L08_03630 8c994a99f8c1a6bd4f60596ba8967a65 209 Gene3D G3DSA:1.10.10.10 2 82 1.1E-11 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L08_03630 8c994a99f8c1a6bd4f60596ba8967a65 209 PIRSF PIRSF019345 2 194 3.8E-46 T 23-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 A3L08_03630 8c994a99f8c1a6bd4f60596ba8967a65 209 Pfam PF04079 Segregation and condensation complex subunit ScpB 9 153 6.8E-36 T 23-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 A3L08_03630 8c994a99f8c1a6bd4f60596ba8967a65 209 TIGRFAM TIGR00281 TIGR00281: segregation and condensation protein B 7 175 1.0E-31 T 23-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 A3L08_07670 a25e8c4dfe1f2f76b46e9a416214d410 369 Gene3D G3DSA:3.40.1280.30 92 237 7.5E-11 T 23-10-2018 IPR038459 tRNA methyltransferase TRM10-type domain superfamily A3L08_07670 a25e8c4dfe1f2f76b46e9a416214d410 369 Pfam PF04252 Predicted SAM-dependent RNA methyltransferase 166 214 1.1E-4 T 23-10-2018 IPR007364 RNA methyltransferase TK0422/Sfm1 GO:0008168 A3L08_07670 a25e8c4dfe1f2f76b46e9a416214d410 369 PIRSF PIRSF018978 1 369 3.8E-178 T 23-10-2018 IPR016742 tRNA methyltransferase, archaea GO:0008175|GO:0030488 A3L08_02365 43c939129c2e508dc8d0c893ab6a805d 198 Pfam PF12389 Camelysin metallo-endopeptidase 5 95 2.0E-5 T 23-10-2018 IPR022121 Peptidase M73, camelysin A3L08_01330 a032f0907dd22b820b3aa827335732c7 394 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 16 240 9.7E-81 T 23-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 A3L08_01330 a032f0907dd22b820b3aa827335732c7 394 Gene3D G3DSA:3.40.50.970 3 252 1.6E-104 T 23-10-2018 A3L08_01330 a032f0907dd22b820b3aa827335732c7 394 SUPERFAMILY SSF52518 5 251 5.1E-70 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold A3L08_01330 a032f0907dd22b820b3aa827335732c7 394 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 262 365 1.1E-28 T 23-10-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II A3L08_01330 a032f0907dd22b820b3aa827335732c7 394 SUPERFAMILY SSF52922 254 370 6.28E-33 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A3L08_01330 a032f0907dd22b820b3aa827335732c7 394 Gene3D G3DSA:3.40.50.920 253 391 1.3E-39 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A3L08_08130 9806c4f866179ccffcee379fad807a92 179 Gene3D G3DSA:3.40.109.10 1 168 3.5E-52 T 23-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A3L08_08130 9806c4f866179ccffcee379fad807a92 179 SUPERFAMILY SSF55469 1 159 3.27E-50 T 23-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A3L08_08130 9806c4f866179ccffcee379fad807a92 179 Pfam PF00881 Nitroreductase family 7 63 3.1E-18 T 23-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 A3L08_06285 83372b392ebe3e9db6ea28c05de31eb6 642 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 14 366 2.3E-81 T 23-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 A3L08_06285 83372b392ebe3e9db6ea28c05de31eb6 642 SUPERFAMILY SSF52374 120 513 1.2E-77 T 23-10-2018 A3L08_06285 83372b392ebe3e9db6ea28c05de31eb6 642 PRINTS PR01038 Arginyl-tRNA synthetase signature 330 351 2.4E-23 T 23-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 A3L08_06285 83372b392ebe3e9db6ea28c05de31eb6 642 PRINTS PR01038 Arginyl-tRNA synthetase signature 125 140 2.4E-23 T 23-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 A3L08_06285 83372b392ebe3e9db6ea28c05de31eb6 642 PRINTS PR01038 Arginyl-tRNA synthetase signature 164 177 2.4E-23 T 23-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 A3L08_06285 83372b392ebe3e9db6ea28c05de31eb6 642 PRINTS PR01038 Arginyl-tRNA synthetase signature 140 156 2.4E-23 T 23-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 A3L08_06285 83372b392ebe3e9db6ea28c05de31eb6 642 Gene3D G3DSA:3.30.1360.70 6 121 4.5E-32 T 23-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 A3L08_06285 83372b392ebe3e9db6ea28c05de31eb6 642 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 135 144 - T 23-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L08_06285 83372b392ebe3e9db6ea28c05de31eb6 642 SUPERFAMILY SSF55190 7 116 1.7E-19 T 23-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 A3L08_06285 83372b392ebe3e9db6ea28c05de31eb6 642 Hamap MF_00123 Arginine--tRNA ligase [argS]. 12 642 28.157 T 23-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 A3L08_06285 83372b392ebe3e9db6ea28c05de31eb6 642 SMART SM00836 520 642 5.8E-52 T 23-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 A3L08_06285 83372b392ebe3e9db6ea28c05de31eb6 642 Gene3D G3DSA:3.40.50.620 122 523 3.7E-160 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L08_06285 83372b392ebe3e9db6ea28c05de31eb6 642 SUPERFAMILY SSF47323 516 642 1.57E-35 T 23-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L08_06285 83372b392ebe3e9db6ea28c05de31eb6 642 SMART SM01016 8 95 2.8E-22 T 23-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A3L08_06285 83372b392ebe3e9db6ea28c05de31eb6 642 Pfam PF05746 DALR anticodon binding domain 520 642 3.5E-37 T 23-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 A3L08_06285 83372b392ebe3e9db6ea28c05de31eb6 642 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 14 95 9.4E-15 T 23-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A3L08_06285 83372b392ebe3e9db6ea28c05de31eb6 642 Pfam PF00750 tRNA synthetases class I (R) 388 492 5.6E-11 T 23-10-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 A3L08_06285 83372b392ebe3e9db6ea28c05de31eb6 642 Pfam PF00750 tRNA synthetases class I (R) 105 361 2.1E-26 T 23-10-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 A3L08_06285 83372b392ebe3e9db6ea28c05de31eb6 642 Gene3D G3DSA:1.10.730.10 524 642 1.0E-42 T 23-10-2018 A3L08_06680 42c2b72ce7ea60f90a777d33528ace07 218 SUPERFAMILY SSF56300 1 211 3.28E-70 T 23-10-2018 A3L08_06680 42c2b72ce7ea60f90a777d33528ace07 218 Gene3D G3DSA:3.60.21.10 1 214 4.0E-43 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like A3L08_06680 42c2b72ce7ea60f90a777d33528ace07 218 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 1 203 3.6E-20 T 23-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 A3L08_01045 467bec3c58ea61c84844c6ec468a5fb0 145 Pfam PF04073 Aminoacyl-tRNA editing domain 21 133 1.2E-28 T 23-10-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 A3L08_01045 467bec3c58ea61c84844c6ec468a5fb0 145 SUPERFAMILY SSF55826 13 144 5.36E-31 T 23-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 A3L08_01045 467bec3c58ea61c84844c6ec468a5fb0 145 Gene3D G3DSA:3.90.960.10 1 144 3.9E-38 T 23-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 A3L08_05955 fa7e5d905b7806b589d3455d72ee398f 201 Gene3D G3DSA:3.60.15.10 2 198 3.3E-42 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L08_05955 fa7e5d905b7806b589d3455d72ee398f 201 SMART SM00849 16 180 1.3E-33 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L08_05955 fa7e5d905b7806b589d3455d72ee398f 201 SUPERFAMILY SSF56281 2 199 6.55E-44 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L08_05955 fa7e5d905b7806b589d3455d72ee398f 201 Pfam PF00753 Metallo-beta-lactamase superfamily 16 164 4.9E-21 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L08_02450 bf112d55f13a0ba23b69abe29a177d4a 459 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 261 298 - T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A3L08_02450 bf112d55f13a0ba23b69abe29a177d4a 459 SUPERFAMILY SSF53383 34 444 1.31E-116 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A3L08_02450 bf112d55f13a0ba23b69abe29a177d4a 459 Gene3D G3DSA:3.40.640.10 73 343 1.2E-141 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A3L08_02450 bf112d55f13a0ba23b69abe29a177d4a 459 PIRSF PIRSF000521 137 446 4.3E-33 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A3L08_02450 bf112d55f13a0ba23b69abe29a177d4a 459 PIRSF PIRSF000521 1 143 7.5E-11 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A3L08_02450 bf112d55f13a0ba23b69abe29a177d4a 459 Gene3D G3DSA:3.90.1150.10 19 439 1.2E-141 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A3L08_02450 bf112d55f13a0ba23b69abe29a177d4a 459 Pfam PF00202 Aminotransferase class-III 37 443 4.3E-100 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A3L08_03275 6140844d9d8c80ddd01a1afc2d502fc8 714 TIGRFAM TIGR01736 FGAM_synth_II: phosphoribosylformylglycinamidine synthase II 3 705 2.3E-295 T 23-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A3L08_03275 6140844d9d8c80ddd01a1afc2d502fc8 714 SUPERFAMILY SSF55326 19 178 7.33E-48 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A3L08_03275 6140844d9d8c80ddd01a1afc2d502fc8 714 Pfam PF02769 AIR synthase related protein, C-terminal domain 557 680 4.4E-21 T 23-10-2018 IPR010918 PurM-like, C-terminal domain A3L08_03275 6140844d9d8c80ddd01a1afc2d502fc8 714 Pfam PF02769 AIR synthase related protein, C-terminal domain 185 340 3.2E-35 T 23-10-2018 IPR010918 PurM-like, C-terminal domain A3L08_03275 6140844d9d8c80ddd01a1afc2d502fc8 714 Hamap MF_00420 Phosphoribosylformylglycinamidine synthase subunit PurL [purL]. 1 714 260.924 T 23-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A3L08_03275 6140844d9d8c80ddd01a1afc2d502fc8 714 SUPERFAMILY SSF55326 376 534 1.57E-49 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A3L08_03275 6140844d9d8c80ddd01a1afc2d502fc8 714 Gene3D G3DSA:3.30.1330.10 27 175 2.8E-122 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A3L08_03275 6140844d9d8c80ddd01a1afc2d502fc8 714 Gene3D G3DSA:3.90.650.10 543 710 5.7E-38 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A3L08_03275 6140844d9d8c80ddd01a1afc2d502fc8 714 SUPERFAMILY SSF56042 545 706 6.58E-37 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A3L08_03275 6140844d9d8c80ddd01a1afc2d502fc8 714 SUPERFAMILY SSF56042 184 402 3.44E-51 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A3L08_03275 6140844d9d8c80ddd01a1afc2d502fc8 714 Gene3D G3DSA:3.90.650.10 12 340 2.8E-122 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A3L08_03275 6140844d9d8c80ddd01a1afc2d502fc8 714 PIRSF PIRSF001587 1 713 3.0E-286 T 23-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A3L08_03275 6140844d9d8c80ddd01a1afc2d502fc8 714 Gene3D G3DSA:3.30.1330.10 363 535 5.1E-56 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A3L08_03275 6140844d9d8c80ddd01a1afc2d502fc8 714 Pfam PF00586 AIR synthase related protein, N-terminal domain 67 172 4.3E-25 T 23-10-2018 IPR016188 PurM-like, N-terminal domain A3L08_03275 6140844d9d8c80ddd01a1afc2d502fc8 714 Pfam PF00586 AIR synthase related protein, N-terminal domain 429 533 2.4E-20 T 23-10-2018 IPR016188 PurM-like, N-terminal domain A3L08_01075 572d0fc5afaa0bded46b674194796375 300 Gene3D G3DSA:3.40.225.10 120 299 1.5E-44 T 23-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily A3L08_01075 572d0fc5afaa0bded46b674194796375 300 Gene3D G3DSA:1.10.260.40 18 80 9.0E-7 T 23-10-2018 A3L08_01075 572d0fc5afaa0bded46b674194796375 300 Pfam PF01381 Helix-turn-helix 27 64 9.7E-8 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A3L08_01075 572d0fc5afaa0bded46b674194796375 300 SUPERFAMILY SSF53639 125 296 6.28E-46 T 23-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily A3L08_01075 572d0fc5afaa0bded46b674194796375 300 SMART SM00530 15 84 0.0034 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A3L08_01075 572d0fc5afaa0bded46b674194796375 300 Pfam PF10120 Thiamine-phosphate synthase 133 291 7.6E-46 T 23-10-2018 IPR019293 Thiamine-phosphate synthase ThiN GO:0004789 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A3L08_01075 572d0fc5afaa0bded46b674194796375 300 SUPERFAMILY SSF47413 16 64 1.47E-8 T 23-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A3L08_03750 d375826b11032daa6bb157aed5649af5 391 SUPERFAMILY SSF103473 11 385 2.75E-48 T 23-10-2018 IPR036259 MFS transporter superfamily A3L08_03750 d375826b11032daa6bb157aed5649af5 391 Gene3D G3DSA:1.20.1250.20 209 384 1.2E-19 T 23-10-2018 A3L08_03750 d375826b11032daa6bb157aed5649af5 391 Gene3D G3DSA:1.20.1250.20 8 208 8.8E-21 T 23-10-2018 A3L08_03750 d375826b11032daa6bb157aed5649af5 391 Pfam PF07690 Major Facilitator Superfamily 214 383 2.0E-15 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A3L08_03750 d375826b11032daa6bb157aed5649af5 391 Pfam PF07690 Major Facilitator Superfamily 20 186 1.4E-17 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A3L08_07285 9e52cbb15eac51a26387964b30f2e793 602 Gene3D G3DSA:3.40.50.10490 250 601 2.2E-137 T 23-10-2018 A3L08_07285 9e52cbb15eac51a26387964b30f2e793 602 Pfam PF01380 SIS domain 284 412 1.0E-33 T 23-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 A3L08_07285 9e52cbb15eac51a26387964b30f2e793 602 Pfam PF01380 SIS domain 457 584 5.5E-23 T 23-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 A3L08_07285 9e52cbb15eac51a26387964b30f2e793 602 SUPERFAMILY SSF56235 2 229 1.12E-73 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A3L08_07285 9e52cbb15eac51a26387964b30f2e793 602 Gene3D G3DSA:3.40.50.10490 442 587 2.2E-137 T 23-10-2018 A3L08_07285 9e52cbb15eac51a26387964b30f2e793 602 SUPERFAMILY SSF53697 247 602 2.32E-111 T 23-10-2018 A3L08_07285 9e52cbb15eac51a26387964b30f2e793 602 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 602 2.7E-246 T 23-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 A3L08_07285 9e52cbb15eac51a26387964b30f2e793 602 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 602 40.75 T 23-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 A3L08_07285 9e52cbb15eac51a26387964b30f2e793 602 Pfam PF13522 Glutamine amidotransferase domain 67 186 2.8E-21 T 23-10-2018 A3L08_07285 9e52cbb15eac51a26387964b30f2e793 602 Gene3D G3DSA:3.60.20.10 2 239 1.5E-76 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A3L08_09170 e86d86187b88280edd7c676dfaebe8a5 259 SUPERFAMILY SSF52540 3 236 2.44E-58 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_09170 e86d86187b88280edd7c676dfaebe8a5 259 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 6 212 6.0E-24 T 23-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain A3L08_09170 e86d86187b88280edd7c676dfaebe8a5 259 SMART SM00382 3 163 0.0031 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L08_09170 e86d86187b88280edd7c676dfaebe8a5 259 Gene3D G3DSA:3.40.50.300 4 233 1.4E-66 T 23-10-2018 A3L08_09170 e86d86187b88280edd7c676dfaebe8a5 259 TIGRFAM TIGR01969 minD_arch: cell division ATPase MinD 4 251 7.8E-117 T 23-10-2018 IPR010224 ATP binding protein MinD, archaea A3L08_09170 e86d86187b88280edd7c676dfaebe8a5 259 PIRSF PIRSF003092 1 259 3.2E-65 T 23-10-2018 IPR025501 ATP binding protein MinD A3L08_04005 2bc46b8d80521cf061eea7094b08de32 392 Gene3D G3DSA:3.90.1150.10 13 381 8.8E-68 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A3L08_04005 2bc46b8d80521cf061eea7094b08de32 392 Pfam PF00266 Aminotransferase class-V 275 382 8.8E-8 T 23-10-2018 IPR000192 Aminotransferase class V domain A3L08_04005 2bc46b8d80521cf061eea7094b08de32 392 Pfam PF00266 Aminotransferase class-V 57 236 2.8E-21 T 23-10-2018 IPR000192 Aminotransferase class V domain A3L08_04005 2bc46b8d80521cf061eea7094b08de32 392 SUPERFAMILY SSF53383 2 386 5.03E-61 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A3L08_04005 2bc46b8d80521cf061eea7094b08de32 392 Gene3D G3DSA:3.40.640.10 25 298 8.8E-68 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A3L08_06070 f3b9708d752b92718dc0ca3e3b82a502 440 Gene3D G3DSA:3.40.50.300 17 349 1.8E-112 T 23-10-2018 A3L08_06070 f3b9708d752b92718dc0ca3e3b82a502 440 SUPERFAMILY SSF52540 37 423 1.69E-40 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_06070 f3b9708d752b92718dc0ca3e3b82a502 440 Pfam PF06068 TIP49 C-terminus 14 403 2.7E-160 T 23-10-2018 IPR010339 TIP49, C-terminal GO:0003678|GO:0005524 Reactome: R-HSA-171319|Reactome: R-HSA-3214847 A3L08_06070 f3b9708d752b92718dc0ca3e3b82a502 440 Gene3D G3DSA:2.40.50.360 119 243 1.8E-112 T 23-10-2018 A3L08_06070 f3b9708d752b92718dc0ca3e3b82a502 440 SMART SM00382 62 353 1.4E-12 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L08_06070 f3b9708d752b92718dc0ca3e3b82a502 440 Gene3D G3DSA:1.10.8.60 354 438 5.3E-26 T 23-10-2018 A3L08_04755 0cf1b0d1d43fd12f31b60a2a4f7b64cf 728 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 308 322 - T 23-10-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 A3L08_04755 0cf1b0d1d43fd12f31b60a2a4f7b64cf 728 Gene3D G3DSA:1.10.290.10 279 406 1.3E-124 T 23-10-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 A3L08_04755 0cf1b0d1d43fd12f31b60a2a4f7b64cf 728 SMART SM00437 271 527 5.3E-105 T 23-10-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 A3L08_04755 0cf1b0d1d43fd12f31b60a2a4f7b64cf 728 SMART SM00436 131 226 9.4E-43 T 23-10-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 A3L08_04755 0cf1b0d1d43fd12f31b60a2a4f7b64cf 728 TIGRFAM TIGR01057 topA_arch: DNA topoisomerase I 6 593 1.1E-275 T 23-10-2018 IPR005739 DNA topoisomerase I, archeal-type GO:0003677|GO:0003916|GO:0006265 A3L08_04755 0cf1b0d1d43fd12f31b60a2a4f7b64cf 728 Hamap MF_00952 DNA topoisomerase 1 [topA]. 2 716 50.857 T 23-10-2018 IPR028612 DNA topoisomerase I, type IA GO:0003677|GO:0003916|GO:0006265 A3L08_04755 0cf1b0d1d43fd12f31b60a2a4f7b64cf 728 Pfam PF01751 Toprim domain 3 139 7.3E-18 T 23-10-2018 IPR006171 TOPRIM domain A3L08_04755 0cf1b0d1d43fd12f31b60a2a4f7b64cf 728 SUPERFAMILY SSF57783 648 686 1.6E-5 T 23-10-2018 A3L08_04755 0cf1b0d1d43fd12f31b60a2a4f7b64cf 728 Gene3D G3DSA:2.70.20.10 220 475 1.3E-124 T 23-10-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 A3L08_04755 0cf1b0d1d43fd12f31b60a2a4f7b64cf 728 SUPERFAMILY SSF56712 2 659 4.97E-164 T 23-10-2018 IPR023405 DNA topoisomerase, type IA, core domain A3L08_04755 0cf1b0d1d43fd12f31b60a2a4f7b64cf 728 Pfam PF01131 DNA topoisomerase 156 564 5.6E-134 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A3L08_04755 0cf1b0d1d43fd12f31b60a2a4f7b64cf 728 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 647 684 9.4E-14 T 23-10-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 A3L08_04755 0cf1b0d1d43fd12f31b60a2a4f7b64cf 728 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 491 505 6.8E-25 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A3L08_04755 0cf1b0d1d43fd12f31b60a2a4f7b64cf 728 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 103 116 6.8E-25 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A3L08_04755 0cf1b0d1d43fd12f31b60a2a4f7b64cf 728 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 196 214 6.8E-25 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A3L08_04755 0cf1b0d1d43fd12f31b60a2a4f7b64cf 728 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 313 322 6.8E-25 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A3L08_04755 0cf1b0d1d43fd12f31b60a2a4f7b64cf 728 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 392 408 6.8E-25 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A3L08_04755 0cf1b0d1d43fd12f31b60a2a4f7b64cf 728 SMART SM00493 2 129 2.6E-19 T 23-10-2018 IPR006171 TOPRIM domain A3L08_04755 0cf1b0d1d43fd12f31b60a2a4f7b64cf 728 Gene3D G3DSA:3.40.50.140 1 154 1.7E-30 T 23-10-2018 A3L08_04755 0cf1b0d1d43fd12f31b60a2a4f7b64cf 728 Gene3D G3DSA:1.10.460.10 163 575 1.3E-124 T 23-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 A3L08_06470 6642cc456cdd680b04b04e8e5279f8c4 143 SUPERFAMILY SSF88723 1 131 1.4E-20 T 23-10-2018 IPR029060 PIN-like domain superfamily A3L08_06470 6642cc456cdd680b04b04e8e5279f8c4 143 Gene3D G3DSA:3.40.50.1010 4 140 1.7E-14 T 23-10-2018 A3L08_06470 6642cc456cdd680b04b04e8e5279f8c4 143 Pfam PF01850 PIN domain 5 130 3.8E-21 T 23-10-2018 IPR002716 PIN domain A3L08_06470 6642cc456cdd680b04b04e8e5279f8c4 143 SMART SM00670 2 131 8.0E-19 T 23-10-2018 IPR002716 PIN domain A3L08_00950 09dfde7a84445bd98bba18e82723549e 471 Pfam PF04167 Protein of unknown function (DUF402) 379 442 1.0E-13 T 23-10-2018 IPR007295 Domain of unknown function DUF402 A3L08_00950 09dfde7a84445bd98bba18e82723549e 471 SUPERFAMILY SSF159234 321 471 3.27E-29 T 23-10-2018 IPR035930 FomD-like superfamily A3L08_00950 09dfde7a84445bd98bba18e82723549e 471 Gene3D G3DSA:2.40.380.10 344 471 2.6E-9 T 23-10-2018 IPR035930 FomD-like superfamily A3L08_00950 09dfde7a84445bd98bba18e82723549e 471 PIRSF PIRSF018644 5 471 4.6E-192 T 23-10-2018 IPR016730 RNA-binding AU-1 GO:0003723 A3L08_00950 09dfde7a84445bd98bba18e82723549e 471 SMART SM00316 92 152 0.0035 T 23-10-2018 IPR022967 RNA-binding domain, S1 A3L08_00950 09dfde7a84445bd98bba18e82723549e 471 Hamap MF_01910 RNA-binding protein AU-1 [aubA]. 7 471 33.922 T 23-10-2018 IPR016730 RNA-binding AU-1 GO:0003723 A3L08_00950 09dfde7a84445bd98bba18e82723549e 471 Pfam PF10150 Ribonuclease E/G family 152 263 2.8E-11 T 23-10-2018 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 A3L08_08625 477e26fcdf61980657dcd3b87bfd7ff6 422 Pfam PF07690 Major Facilitator Superfamily 42 384 8.3E-26 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A3L08_08625 477e26fcdf61980657dcd3b87bfd7ff6 422 SUPERFAMILY SSF103473 40 419 2.62E-45 T 23-10-2018 IPR036259 MFS transporter superfamily A3L08_08625 477e26fcdf61980657dcd3b87bfd7ff6 422 Gene3D G3DSA:1.20.1250.20 32 419 2.8E-41 T 23-10-2018 A3L08_05615 b38800b0fcec7952e23599d1763f2635 159 SUPERFAMILY SSF159902 1 155 1.44E-69 T 23-10-2018 A3L08_05615 b38800b0fcec7952e23599d1763f2635 159 Pfam PF09638 Ph1570 protein 1 155 2.2E-80 T 23-10-2018 IPR023110 PH1570-like domain A3L08_05615 b38800b0fcec7952e23599d1763f2635 159 Gene3D G3DSA:3.40.1600.10 1 155 2.9E-69 T 23-10-2018 IPR036807 PH1570-like superfamily A3L08_07175 5680e2539148e6acd19a4c637903bf05 695 SMART SM00642 224 613 3.2E-104 T 23-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 A3L08_07175 5680e2539148e6acd19a4c637903bf05 695 Pfam PF00128 Alpha amylase, catalytic domain 278 583 7.1E-63 T 23-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 A3L08_07175 5680e2539148e6acd19a4c637903bf05 695 Pfam PF16561 Glycogen recognition site of AMP-activated protein kinase 14 76 4.0E-11 T 23-10-2018 IPR032640 AMP-activated protein kinase, glycogen-binding domain Reactome: R-HSA-1445148|Reactome: R-HSA-1632852|Reactome: R-HSA-2151209|Reactome: R-HSA-380972|Reactome: R-HSA-5628897|Reactome: R-HSA-6804756 A3L08_07175 5680e2539148e6acd19a4c637903bf05 695 Pfam PF11941 Domain of unknown function (DUF3459) 606 691 9.0E-6 T 23-10-2018 IPR022567 Glycosyl hydrolase, C-terminal (DUF3459) A3L08_07175 5680e2539148e6acd19a4c637903bf05 695 Gene3D G3DSA:3.20.20.80 210 615 3.6E-120 T 23-10-2018 A3L08_07175 5680e2539148e6acd19a4c637903bf05 695 Gene3D G3DSA:2.60.40.10 3 107 8.3E-20 T 23-10-2018 IPR013783 Immunoglobulin-like fold A3L08_07175 5680e2539148e6acd19a4c637903bf05 695 SUPERFAMILY SSF81296 26 107 5.6E-15 T 23-10-2018 IPR014756 Immunoglobulin E-set A3L08_07175 5680e2539148e6acd19a4c637903bf05 695 SUPERFAMILY SSF51445 155 620 1.95E-107 T 23-10-2018 IPR017853 Glycoside hydrolase superfamily A3L08_04310 705e6b68f905d7df46c42bfdfb0e7f9a 149 SUPERFAMILY SSF54909 61 145 3.49E-17 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel A3L08_04310 705e6b68f905d7df46c42bfdfb0e7f9a 149 SMART SM00344 1 107 7.1E-43 T 23-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A3L08_04310 705e6b68f905d7df46c42bfdfb0e7f9a 149 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 1.2E-13 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L08_04310 705e6b68f905d7df46c42bfdfb0e7f9a 149 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 1.2E-13 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L08_04310 705e6b68f905d7df46c42bfdfb0e7f9a 149 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 1.2E-13 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L08_04310 705e6b68f905d7df46c42bfdfb0e7f9a 149 Gene3D G3DSA:3.30.70.920 53 146 4.2E-22 T 23-10-2018 A3L08_04310 705e6b68f905d7df46c42bfdfb0e7f9a 149 Pfam PF13412 Winged helix-turn-helix DNA-binding 2 48 1.2E-17 T 23-10-2018 A3L08_04310 705e6b68f905d7df46c42bfdfb0e7f9a 149 Pfam PF01037 Lrp/AsnC ligand binding domain 67 136 2.5E-14 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A3L08_04310 705e6b68f905d7df46c42bfdfb0e7f9a 149 Gene3D G3DSA:1.10.10.10 1 51 5.3E-21 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L08_04310 705e6b68f905d7df46c42bfdfb0e7f9a 149 SUPERFAMILY SSF46785 1 61 2.25E-17 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L08_01780 339e48bba261b3fb1bb93f5a1fc27fae 173 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 44 153 3.3E-28 T 23-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L08_01780 339e48bba261b3fb1bb93f5a1fc27fae 173 Gene3D G3DSA:3.40.50.12280 3 171 9.3E-53 T 23-10-2018 A3L08_01780 339e48bba261b3fb1bb93f5a1fc27fae 173 SUPERFAMILY SSF56770 31 161 1.44E-53 T 23-10-2018 A3L08_05715 455ceb9b8c0a5f05d2184985c1f6343d 386 SUPERFAMILY SSF55120 272 383 1.98E-11 T 23-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 A3L08_05715 455ceb9b8c0a5f05d2184985c1f6343d 386 TIGRFAM TIGR01213 pseudo_Pus10arc: tRNA pseudouridine(54/55) synthase 8 385 1.9E-145 T 23-10-2018 IPR005912 tRNA pseudouridine synthase, Pus10 GO:0000049|GO:0001522|GO:0006400|GO:0009982 A3L08_05715 455ceb9b8c0a5f05d2184985c1f6343d 386 Pfam PF02926 THUMP domain 22 162 1.2E-8 T 23-10-2018 IPR004114 THUMP domain GO:0003723 A3L08_05715 455ceb9b8c0a5f05d2184985c1f6343d 386 Hamap MF_01893 tRNA pseudouridine synthase Pus10 [pus10]. 7 385 51.967 T 23-10-2018 IPR005912 tRNA pseudouridine synthase, Pus10 GO:0000049|GO:0001522|GO:0006400|GO:0009982 A3L08_05715 455ceb9b8c0a5f05d2184985c1f6343d 386 Gene3D G3DSA:3.30.70.3190 276 384 1.4E-29 T 23-10-2018 A3L08_05715 455ceb9b8c0a5f05d2184985c1f6343d 386 Gene3D G3DSA:3.30.70.2510 162 275 6.2E-30 T 23-10-2018 A3L08_08020 955709d73352e571a705c25f7f05d85e 201 Pfam PF13412 Winged helix-turn-helix DNA-binding 5 52 9.9E-17 T 23-10-2018 A3L08_08020 955709d73352e571a705c25f7f05d85e 201 Gene3D G3DSA:1.10.10.10 1 56 1.3E-21 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L08_08020 955709d73352e571a705c25f7f05d85e 201 ProSitePatterns PS00519 AsnC-type HTH domain signature. 23 49 - T 23-10-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site A3L08_08020 955709d73352e571a705c25f7f05d85e 201 SMART SM00746 145 181 3.0E-10 T 23-10-2018 IPR011017 TRASH domain A3L08_08020 955709d73352e571a705c25f7f05d85e 201 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 32 51 2.9E-15 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L08_08020 955709d73352e571a705c25f7f05d85e 201 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 5 21 2.9E-15 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L08_08020 955709d73352e571a705c25f7f05d85e 201 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 21 32 2.9E-15 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L08_08020 955709d73352e571a705c25f7f05d85e 201 SMART SM00344 5 104 7.8E-21 T 23-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A3L08_08020 955709d73352e571a705c25f7f05d85e 201 SUPERFAMILY SSF46785 4 63 3.73E-16 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L08_08020 955709d73352e571a705c25f7f05d85e 201 Pfam PF08394 Archaeal TRASH domain 145 181 1.2E-20 T 23-10-2018 IPR013603 TRASH transcription regulator C-terminal, archaeal A3L08_08020 955709d73352e571a705c25f7f05d85e 201 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 35 51 3.0E-6 T 23-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A3L08_08020 955709d73352e571a705c25f7f05d85e 201 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 21 35 3.0E-6 T 23-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A3L08_07955 cd6d3ae5b33bd226ab073965bcdfdb44 193 Gene3D G3DSA:1.20.58.1030 1 112 1.7E-43 T 23-10-2018 A3L08_07955 cd6d3ae5b33bd226ab073965bcdfdb44 193 Gene3D G3DSA:3.40.5.50 135 192 1.3E-25 T 23-10-2018 A3L08_04425 a5af29c8e17e32b645bb4db8f141b6c5 343 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 83 97 - T 23-10-2018 IPR033749 Polyprenyl synthetase, conserved site A3L08_04425 a5af29c8e17e32b645bb4db8f141b6c5 343 Gene3D G3DSA:1.10.600.10 1 343 2.7E-133 T 23-10-2018 IPR008949 Isoprenoid synthase domain superfamily A3L08_04425 a5af29c8e17e32b645bb4db8f141b6c5 343 SUPERFAMILY SSF48576 4 342 4.0E-96 T 23-10-2018 IPR008949 Isoprenoid synthase domain superfamily A3L08_04425 a5af29c8e17e32b645bb4db8f141b6c5 343 Pfam PF00348 Polyprenyl synthetase 33 270 6.0E-69 T 23-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 A3L08_04425 a5af29c8e17e32b645bb4db8f141b6c5 343 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 210 222 - T 23-10-2018 IPR033749 Polyprenyl synthetase, conserved site A3L08_09415 30a167972b5b86cb127da0fbec41bd67 400 SUPERFAMILY SSF63867 331 399 1.44E-18 T 23-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A3L08_09415 30a167972b5b86cb127da0fbec41bd67 400 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 180 317 5.2E-34 T 23-10-2018 IPR001453 MoaB/Mog domain A3L08_09415 30a167972b5b86cb127da0fbec41bd67 400 SUPERFAMILY SSF53218 181 325 4.45E-42 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily A3L08_09415 30a167972b5b86cb127da0fbec41bd67 400 Gene3D G3DSA:2.40.340.10 329 400 8.7E-26 T 23-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A3L08_09415 30a167972b5b86cb127da0fbec41bd67 400 Pfam PF03453 MoeA N-terminal region (domain I and II) 8 171 3.1E-44 T 23-10-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A3L08_09415 30a167972b5b86cb127da0fbec41bd67 400 Pfam PF03454 MoeA C-terminal region (domain IV) 335 399 1.6E-18 T 23-10-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A3L08_09415 30a167972b5b86cb127da0fbec41bd67 400 Gene3D G3DSA:2.170.190.11 49 145 2.1E-116 T 23-10-2018 A3L08_09415 30a167972b5b86cb127da0fbec41bd67 400 SMART SM00852 184 321 3.0E-36 T 23-10-2018 IPR001453 MoaB/Mog domain A3L08_09415 30a167972b5b86cb127da0fbec41bd67 400 Gene3D G3DSA:3.40.980.10 179 320 2.1E-116 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily A3L08_09415 30a167972b5b86cb127da0fbec41bd67 400 SUPERFAMILY SSF63882 7 180 4.32E-58 T 23-10-2018 IPR036135 MoeA, N-terminal and linker domain superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A3L08_09415 30a167972b5b86cb127da0fbec41bd67 400 Gene3D G3DSA:3.90.105.10 26 178 2.1E-116 T 23-10-2018 A3L08_09415 30a167972b5b86cb127da0fbec41bd67 400 Pfam PF00994 Probable molybdopterin binding domain 184 320 4.9E-24 T 23-10-2018 IPR001453 MoaB/Mog domain A3L08_09045 edd3120db9b99fff15301dc6f2a0d7a6 132 TIGRFAM TIGR03081 metmalonyl_epim: methylmalonyl-CoA epimerase 4 130 1.9E-53 T 23-10-2018 IPR017515 Methylmalonyl-CoA epimerase KEGG: 00280+5.1.99.1|KEGG: 00630+5.1.99.1|KEGG: 00640+5.1.99.1|KEGG: 00720+5.1.99.1|MetaCyc: PWY-5741|MetaCyc: PWY-5743|MetaCyc: PWY-5789|MetaCyc: PWY-6728|MetaCyc: PWY-7384|MetaCyc: PWY-7854|Reactome: R-HSA-71032 A3L08_09045 edd3120db9b99fff15301dc6f2a0d7a6 132 Gene3D G3DSA:3.10.180.10 1 131 1.0E-43 T 23-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A3L08_09045 edd3120db9b99fff15301dc6f2a0d7a6 132 SUPERFAMILY SSF54593 1 131 4.19E-35 T 23-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A3L08_09045 edd3120db9b99fff15301dc6f2a0d7a6 132 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 115 5.9E-26 T 23-10-2018 A3L08_04910 281cff7aa2584847e44faf4a42c6bcb8 277 SUPERFAMILY SSF88713 48 252 4.73E-16 T 23-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 A3L08_04910 281cff7aa2584847e44faf4a42c6bcb8 277 Gene3D G3DSA:3.20.20.370 28 255 3.6E-13 T 23-10-2018 A3L08_04910 281cff7aa2584847e44faf4a42c6bcb8 277 Pfam PF10096 Uncharacterized protein conserved in bacteria (DUF2334) 49 247 5.3E-32 T 23-10-2018 IPR018763 Protein of unknown function DUF2334 A3L08_02435 a276490503f502d5015dc5d703565f03 374 Gene3D G3DSA:1.20.1530.20 1 374 1.4E-85 T 23-10-2018 IPR038770 Sodium/solute symporter superfamily A3L08_02435 a276490503f502d5015dc5d703565f03 374 Pfam PF00999 Sodium/hydrogen exchanger family 8 371 2.3E-66 T 23-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 A3L08_07810 f17a8cfb37a0f7308af878844f687398 153 Pfam PF00578 AhpC/TSA family 7 128 5.1E-33 T 23-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A3L08_07810 f17a8cfb37a0f7308af878844f687398 153 Gene3D G3DSA:3.40.30.10 2 149 5.9E-44 T 23-10-2018 A3L08_07810 f17a8cfb37a0f7308af878844f687398 153 PIRSF PIRSF000239 3 150 1.8E-24 T 23-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A3L08_07810 f17a8cfb37a0f7308af878844f687398 153 SUPERFAMILY SSF52833 7 149 2.39E-44 T 23-10-2018 IPR036249 Thioredoxin-like superfamily A3L08_07950 1645b37eadd43e85b820ee0341a6a594 249 Pfam PF00705 Proliferating cell nuclear antigen, N-terminal domain 4 112 2.7E-17 T 23-10-2018 IPR022648 Proliferating cell nuclear antigen, PCNA, N-terminal GO:0003677|GO:0006275 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 A3L08_07950 1645b37eadd43e85b820ee0341a6a594 249 SUPERFAMILY SSF55979 3 117 4.32E-33 T 23-10-2018 A3L08_07950 1645b37eadd43e85b820ee0341a6a594 249 Pfam PF02747 Proliferating cell nuclear antigen, C-terminal domain 126 245 3.3E-9 T 23-10-2018 IPR022649 Proliferating cell nuclear antigen, PCNA, C-terminal GO:0003677|GO:0006275 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 A3L08_07950 1645b37eadd43e85b820ee0341a6a594 249 TIGRFAM TIGR00590 pcna: proliferating cell nuclear antigen (pcna) 3 249 4.1E-38 T 23-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 A3L08_07950 1645b37eadd43e85b820ee0341a6a594 249 SUPERFAMILY SSF55979 125 247 1.1E-31 T 23-10-2018 A3L08_07950 1645b37eadd43e85b820ee0341a6a594 249 Gene3D G3DSA:3.70.10.10 2 242 5.8E-79 T 23-10-2018 A3L08_07950 1645b37eadd43e85b820ee0341a6a594 249 ProSitePatterns PS01251 Proliferating cell nuclear antigen signature 1. 35 58 - T 23-10-2018 IPR022659 Proliferating cell nuclear antigen, PCNA, conserved site Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 A3L08_07950 1645b37eadd43e85b820ee0341a6a594 249 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 35 53 5.3E-15 T 23-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 A3L08_07950 1645b37eadd43e85b820ee0341a6a594 249 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 57 81 5.3E-15 T 23-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 A3L08_07950 1645b37eadd43e85b820ee0341a6a594 249 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 107 129 5.3E-15 T 23-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 A3L08_07950 1645b37eadd43e85b820ee0341a6a594 249 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 233 249 5.3E-15 T 23-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 A3L08_07950 1645b37eadd43e85b820ee0341a6a594 249 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 195 209 5.3E-15 T 23-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 A3L08_07950 1645b37eadd43e85b820ee0341a6a594 249 Hamap MF_00317 DNA polymerase sliding clamp [pcn]. 3 247 32.876 T 23-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 A3L08_08035 20141ad9f109675913ed6f69abec91ad 455 Pfam PF03008 Archaea bacterial proteins of unknown function 307 400 5.8E-28 T 23-10-2018 IPR004256 Domain of unknown function DUF234, DEXX-box ATPase C-terminal A3L08_08035 20141ad9f109675913ed6f69abec91ad 455 Pfam PF01022 Bacterial regulatory protein, arsR family 240 282 1.4E-4 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L08_08035 20141ad9f109675913ed6f69abec91ad 455 SUPERFAMILY SSF46785 223 351 3.51E-8 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L08_08035 20141ad9f109675913ed6f69abec91ad 455 Pfam PF01637 ATPase domain predominantly from Archaea 5 199 2.3E-22 T 23-10-2018 IPR011579 ATPase domain GO:0005524 A3L08_08035 20141ad9f109675913ed6f69abec91ad 455 Gene3D G3DSA:3.40.50.300 3 164 3.8E-30 T 23-10-2018 A3L08_08035 20141ad9f109675913ed6f69abec91ad 455 SUPERFAMILY SSF52540 3 239 1.4E-36 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_02590 d0d23398b6beda76f8f0936921dbee20 366 Gene3D G3DSA:1.20.1690.10 220 323 2.5E-61 T 23-10-2018 IPR035067 V-type ATPase subunit c Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A3L08_02590 d0d23398b6beda76f8f0936921dbee20 366 TIGRFAM TIGR02923 AhaC: ATP synthase A1, C subunit 32 361 2.6E-106 T 23-10-2018 IPR014272 ATPase, V0 complex, c subunit GO:0033179|GO:0046961 A3L08_02590 d0d23398b6beda76f8f0936921dbee20 366 Gene3D G3DSA:1.20.1690.10 112 209 2.5E-61 T 23-10-2018 IPR035067 V-type ATPase subunit c Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A3L08_02590 d0d23398b6beda76f8f0936921dbee20 366 Pfam PF01992 ATP synthase (C/AC39) subunit 39 360 2.0E-66 T 23-10-2018 IPR002843 ATPase, V0 complex, c/d subunit Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A3L08_02590 d0d23398b6beda76f8f0936921dbee20 366 Gene3D G3DSA:1.10.132.50 35 356 2.5E-61 T 23-10-2018 A3L08_02590 d0d23398b6beda76f8f0936921dbee20 366 SUPERFAMILY SSF103486 35 361 1.15E-79 T 23-10-2018 IPR036079 V-type ATP synthase subunit C-like Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A3L08_02590 d0d23398b6beda76f8f0936921dbee20 366 Hamap MF_00314 V-type ATP synthase subunit C [atpC]. 31 363 25.034 T 23-10-2018 IPR014272 ATPase, V0 complex, c subunit GO:0033179|GO:0046961 A3L08_00245 d15861bc6493fddfc0b36e0e0d6875cc 248 Gene3D G3DSA:3.40.50.300 1 244 1.1E-68 T 23-10-2018 A3L08_00245 d15861bc6493fddfc0b36e0e0d6875cc 248 SMART SM00382 28 211 8.8E-9 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L08_00245 d15861bc6493fddfc0b36e0e0d6875cc 248 Pfam PF00005 ABC transporter 19 162 7.7E-29 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L08_00245 d15861bc6493fddfc0b36e0e0d6875cc 248 SUPERFAMILY SSF52540 3 227 1.71E-60 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_01815 5aa17b92a8d0b1e14673bcf241d1ae01 159 Pfam PF02915 Rubrerythrin 18 154 1.9E-12 T 23-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 A3L08_01815 5aa17b92a8d0b1e14673bcf241d1ae01 159 Gene3D G3DSA:1.20.1260.10 8 157 2.6E-32 T 23-10-2018 IPR012347 Ferritin-like A3L08_01815 5aa17b92a8d0b1e14673bcf241d1ae01 159 SUPERFAMILY SSF47240 14 158 2.14E-25 T 23-10-2018 IPR009078 Ferritin-like superfamily A3L08_03860 3c8a8c1af87ba33fac029de1fd366146 249 Pfam PF01138 3' exoribonuclease family, domain 1 25 154 4.3E-35 T 23-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A3L08_03860 3c8a8c1af87ba33fac029de1fd366146 249 SUPERFAMILY SSF55666 154 241 6.15E-26 T 23-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A3L08_03860 3c8a8c1af87ba33fac029de1fd366146 249 SUPERFAMILY SSF54211 10 180 1.52E-47 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A3L08_03860 3c8a8c1af87ba33fac029de1fd366146 249 Pfam PF03725 3' exoribonuclease family, domain 2 157 222 2.4E-16 T 23-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A3L08_03860 3c8a8c1af87ba33fac029de1fd366146 249 Gene3D G3DSA:3.30.230.70 5 244 3.8E-78 T 23-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A3L08_03860 3c8a8c1af87ba33fac029de1fd366146 249 TIGRFAM TIGR02065 ECX1: exosome complex exonuclease 1 9 238 9.3E-121 T 23-10-2018 IPR011807 Exosome complex component Rrp41 GO:0000178|GO:0006401|GO:0016896 A3L08_03860 3c8a8c1af87ba33fac029de1fd366146 249 Hamap MF_00591 Exosome complex component Rrp41 [rrp41]. 6 242 61.301 T 23-10-2018 IPR011807 Exosome complex component Rrp41 GO:0000178|GO:0006401|GO:0016896 A3L08_07185 5f433e1fa7497f925a3d604d64046a75 63 SUPERFAMILY SSF57829 1 56 9.7E-19 T 23-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 A3L08_07185 5f433e1fa7497f925a3d604d64046a75 63 ProDom PD005132 RIBOSOMAL RRNA-BINDING METAL-BINDING RNA-BINDING ZINC RIBONUCLEOPROTEIN ZINC-FINGER L37 60S L37E 9 51 2.0E-16 T 23-10-2018 IPR001569 Ribosomal protein L37e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_07185 5f433e1fa7497f925a3d604d64046a75 63 Pfam PF01907 Ribosomal protein L37e 3 56 5.4E-21 T 23-10-2018 IPR001569 Ribosomal protein L37e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_07185 5f433e1fa7497f925a3d604d64046a75 63 ProSitePatterns PS01077 Ribosomal protein L37e signature. 4 24 - T 23-10-2018 IPR018267 Ribosomal protein L37e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_07185 5f433e1fa7497f925a3d604d64046a75 63 Gene3D G3DSA:2.20.25.30 1 58 2.1E-19 T 23-10-2018 IPR011331 Ribosomal protein L37ae/L37e GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L08_07185 5f433e1fa7497f925a3d604d64046a75 63 Hamap MF_00547 50S ribosomal protein L37e [rpl37e]. 2 55 20.058 T 23-10-2018 IPR001569 Ribosomal protein L37e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_07380 7208337c482a5fdce171b6420afa3494 428 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 59 74 - T 23-10-2018 IPR031157 Tr-type G domain, conserved site A3L08_07380 7208337c482a5fdce171b6420afa3494 428 Pfam PF03143 Elongation factor Tu C-terminal domain 317 424 2.2E-37 T 23-10-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal A3L08_07380 7208337c482a5fdce171b6420afa3494 428 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 8 190 1.2E-15 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A3L08_07380 7208337c482a5fdce171b6420afa3494 428 SUPERFAMILY SSF52540 3 236 4.01E-74 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_07380 7208337c482a5fdce171b6420afa3494 428 Gene3D G3DSA:2.40.30.10 216 310 5.7E-41 T 23-10-2018 A3L08_07380 7208337c482a5fdce171b6420afa3494 428 Hamap MF_00118_A Elongation factor Tu [tuf]. 2 427 60.908 T 23-10-2018 IPR004539 Translation elongation factor EF1A, eukaryotic/archaeal GO:0003746|GO:0005525|GO:0005737|GO:0006414 Reactome: R-HSA-156842 A3L08_07380 7208337c482a5fdce171b6420afa3494 428 Pfam PF03144 Elongation factor Tu domain 2 235 306 1.5E-17 T 23-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 A3L08_07380 7208337c482a5fdce171b6420afa3494 428 SUPERFAMILY SSF50447 213 315 3.33E-28 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily A3L08_07380 7208337c482a5fdce171b6420afa3494 428 Gene3D G3DSA:2.40.30.10 320 425 9.5E-42 T 23-10-2018 A3L08_07380 7208337c482a5fdce171b6420afa3494 428 TIGRFAM TIGR00483 EF-1_alpha: translation elongation factor EF-1, subunit alpha 1 426 1.1E-211 T 23-10-2018 IPR004539 Translation elongation factor EF1A, eukaryotic/archaeal GO:0003746|GO:0005525|GO:0005737|GO:0006414 Reactome: R-HSA-156842 A3L08_07380 7208337c482a5fdce171b6420afa3494 428 Pfam PF00009 Elongation factor Tu GTP binding domain 5 209 3.2E-57 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L08_07380 7208337c482a5fdce171b6420afa3494 428 SUPERFAMILY SSF50465 321 424 1.01E-39 T 23-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal A3L08_07380 7208337c482a5fdce171b6420afa3494 428 Gene3D G3DSA:3.40.50.300 1 212 2.5E-86 T 23-10-2018 A3L08_07380 7208337c482a5fdce171b6420afa3494 428 PRINTS PR00315 GTP-binding elongation factor signature 66 74 2.4E-24 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L08_07380 7208337c482a5fdce171b6420afa3494 428 PRINTS PR00315 GTP-binding elongation factor signature 102 113 2.4E-24 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L08_07380 7208337c482a5fdce171b6420afa3494 428 PRINTS PR00315 GTP-binding elongation factor signature 139 148 2.4E-24 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L08_07380 7208337c482a5fdce171b6420afa3494 428 PRINTS PR00315 GTP-binding elongation factor signature 86 96 2.4E-24 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L08_07380 7208337c482a5fdce171b6420afa3494 428 PRINTS PR00315 GTP-binding elongation factor signature 9 22 2.4E-24 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L08_08820 321692b2eec5c2a5a1e8fe72935223d5 204 SUPERFAMILY SSF75689 4 38 1.16E-5 T 23-10-2018 IPR016190 Translation initiation factor IF2/IF5, zinc-binding GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 A3L08_08820 321692b2eec5c2a5a1e8fe72935223d5 204 Pfam PF01873 Domain found in IF2B/IF5 2 34 6.2E-5 T 23-10-2018 IPR002735 Translation initiation factor IF2/IF5 GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 A3L08_08820 321692b2eec5c2a5a1e8fe72935223d5 204 PIRSF PIRSF015877 1 199 1.4E-67 T 23-10-2018 IPR012041 Uncharacterised conserved protein UCP015877, zinc finger-containing A3L08_08070 b3baed284b37f39948f3bd23ee863803 394 Pfam PF01769 Divalent cation transporter 60 184 1.1E-21 T 23-10-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 A3L08_08070 b3baed284b37f39948f3bd23ee863803 394 Pfam PF01769 Divalent cation transporter 262 387 1.3E-17 T 23-10-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 A3L08_08070 b3baed284b37f39948f3bd23ee863803 394 SUPERFAMILY SSF161093 17 189 1.31E-30 T 23-10-2018 IPR036739 SLC41 divalent cation transporters, integral membrane domain superfamily GO:0006812|GO:0008324 A3L08_08070 b3baed284b37f39948f3bd23ee863803 394 Gene3D G3DSA:1.10.357.20 16 190 1.8E-10 T 23-10-2018 IPR038048 Magnesium transporter MgtE, transmembrane domain A3L08_08070 b3baed284b37f39948f3bd23ee863803 394 Gene3D G3DSA:1.10.357.20 217 394 8.2E-16 T 23-10-2018 IPR038048 Magnesium transporter MgtE, transmembrane domain A3L08_08070 b3baed284b37f39948f3bd23ee863803 394 SUPERFAMILY SSF161093 224 393 7.45E-27 T 23-10-2018 IPR036739 SLC41 divalent cation transporters, integral membrane domain superfamily GO:0006812|GO:0008324 A3L08_07015 5b6e568420d0063d6983632e44c0c980 234 SUPERFAMILY SSF52540 3 227 4.46E-40 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_07015 5b6e568420d0063d6983632e44c0c980 234 SMART SM00382 23 190 0.0092 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L08_07015 5b6e568420d0063d6983632e44c0c980 234 PRINTS PR01874 DNA repair protein radA signature 15 43 1.0E-9 T 23-10-2018 A3L08_07015 5b6e568420d0063d6983632e44c0c980 234 PRINTS PR01874 DNA repair protein radA signature 57 74 1.0E-9 T 23-10-2018 A3L08_07015 5b6e568420d0063d6983632e44c0c980 234 Gene3D G3DSA:3.40.50.300 3 230 1.4E-56 T 23-10-2018 A3L08_07015 5b6e568420d0063d6983632e44c0c980 234 Pfam PF06745 KaiC 6 228 5.4E-50 T 23-10-2018 IPR014774 KaiC-like domain A3L08_09650 116cd606349429ebea4d5977ce7d1c64 578 Pfam PF00664 ABC transporter transmembrane region 24 293 2.0E-44 T 23-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 A3L08_09650 116cd606349429ebea4d5977ce7d1c64 578 Pfam PF00005 ABC transporter 355 503 1.3E-36 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L08_09650 116cd606349429ebea4d5977ce7d1c64 578 SUPERFAMILY SSF52540 328 572 1.78E-84 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_09650 116cd606349429ebea4d5977ce7d1c64 578 SMART SM00382 364 558 1.3E-17 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L08_09650 116cd606349429ebea4d5977ce7d1c64 578 SUPERFAMILY SSF90123 10 326 9.16E-73 T 23-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A3L08_09650 116cd606349429ebea4d5977ce7d1c64 578 Gene3D G3DSA:3.40.50.300 329 577 2.4E-92 T 23-10-2018 A3L08_09650 116cd606349429ebea4d5977ce7d1c64 578 ProSitePatterns PS00211 ABC transporters family signature. 476 490 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L08_09650 116cd606349429ebea4d5977ce7d1c64 578 Gene3D G3DSA:1.20.1560.10 2 326 1.6E-80 T 23-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A3L08_00860 7c6ff3f8de801987069e3f423598f641 390 PRINTS PR01035 Tetracycline resistance protein signature 298 318 6.0E-7 T 23-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A3L08_00860 7c6ff3f8de801987069e3f423598f641 390 PRINTS PR01035 Tetracycline resistance protein signature 43 62 6.0E-7 T 23-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A3L08_00860 7c6ff3f8de801987069e3f423598f641 390 PRINTS PR01035 Tetracycline resistance protein signature 135 157 6.0E-7 T 23-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A3L08_00860 7c6ff3f8de801987069e3f423598f641 390 Pfam PF07690 Major Facilitator Superfamily 13 347 9.6E-45 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A3L08_00860 7c6ff3f8de801987069e3f423598f641 390 SUPERFAMILY SSF103473 6 382 2.88E-57 T 23-10-2018 IPR036259 MFS transporter superfamily A3L08_00860 7c6ff3f8de801987069e3f423598f641 390 Gene3D G3DSA:1.20.1250.20 2 383 8.9E-52 T 23-10-2018 A3L08_00870 d69f65f9492ff5e6b76b02532bdfb9fd 304 Gene3D G3DSA:1.20.58.220 135 236 7.1E-13 T 23-10-2018 IPR038078 PhoU-like domain superfamily A3L08_00870 d69f65f9492ff5e6b76b02532bdfb9fd 304 SMART SM00966 8 54 2.9E-9 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 A3L08_00870 d69f65f9492ff5e6b76b02532bdfb9fd 304 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 8 51 2.9E-8 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 A3L08_00870 d69f65f9492ff5e6b76b02532bdfb9fd 304 SUPERFAMILY SSF109755 125 301 7.59E-19 T 23-10-2018 A3L08_00870 d69f65f9492ff5e6b76b02532bdfb9fd 304 Pfam PF01895 PhoU domain 138 230 2.4E-15 T 23-10-2018 IPR026022 PhoU domain A3L08_06320 0dec6c125b29b37db8c586f7576e1174 502 Pfam PF09852 Predicted membrane protein (DUF2079) 27 444 1.5E-61 T 23-10-2018 IPR018650 Sulfolobus virus STSV1, Orf64 A3L08_06170 6e49a5f7081068fcf054857dccc9ccb1 210 Pfam PF12838 4Fe-4S dicluster domain 60 110 4.1E-11 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L08_06170 6e49a5f7081068fcf054857dccc9ccb1 210 SUPERFAMILY SSF54862 40 140 3.35E-23 T 23-10-2018 A3L08_06170 6e49a5f7081068fcf054857dccc9ccb1 210 Gene3D G3DSA:3.30.70.3270 39 176 9.2E-23 T 23-10-2018 A3L08_06170 6e49a5f7081068fcf054857dccc9ccb1 210 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 96 107 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L08_07545 7ad0eb98bfafad1ef21f29ba87244f29 152 Gene3D G3DSA:2.30.130.90 53 150 1.6E-8 T 23-10-2018 A3L08_07545 7ad0eb98bfafad1ef21f29ba87244f29 152 Pfam PF13636 RNA-binding PUA-like domain of methyltransferase RsmF 100 147 1.3E-12 T 23-10-2018 IPR027391 rRNA small subunit methyltransferase F, RNA-binding PUA-like domain A3L08_01725 82439590dbaf8d3b9eb873c0849d2b8a 425 Pfam PF04055 Radical SAM superfamily 142 314 4.8E-26 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L08_01725 82439590dbaf8d3b9eb873c0849d2b8a 425 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 3 421 2.0E-130 T 23-10-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 A3L08_01725 82439590dbaf8d3b9eb873c0849d2b8a 425 SMART SM00729 138 355 4.9E-62 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A3L08_01725 82439590dbaf8d3b9eb873c0849d2b8a 425 Pfam PF01938 TRAM domain 366 424 6.0E-10 T 23-10-2018 IPR002792 TRAM domain A3L08_01725 82439590dbaf8d3b9eb873c0849d2b8a 425 Pfam PF00919 Uncharacterized protein family UPF0004 3 85 5.4E-21 T 23-10-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 A3L08_01725 82439590dbaf8d3b9eb873c0849d2b8a 425 Gene3D G3DSA:3.80.30.20 138 369 8.7E-76 T 23-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe A3L08_01725 82439590dbaf8d3b9eb873c0849d2b8a 425 Gene3D G3DSA:3.40.50.12160 2 124 1.1E-24 T 23-10-2018 IPR038135 Methylthiotransferase, N-terminal domain superfamily A3L08_01725 82439590dbaf8d3b9eb873c0849d2b8a 425 TIGRFAM TIGR01578 MiaB-like-B: MiaB-like tRNA modifying enzyme, archaeal-type 3 422 3.4E-142 T 23-10-2018 IPR006466 MiaB-like tRNA modifying enzyme, archaeal-type Reactome: R-HSA-6782315 A3L08_01725 82439590dbaf8d3b9eb873c0849d2b8a 425 SUPERFAMILY SSF102114 128 359 1.02E-52 T 23-10-2018 A3L08_01725 82439590dbaf8d3b9eb873c0849d2b8a 425 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 142 162 - T 23-10-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 A3L08_07775 041eb4b316d0e7999a4145e08e1508c5 276 SUPERFAMILY SSF56281 1 274 9.17E-38 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L08_07775 041eb4b316d0e7999a4145e08e1508c5 276 Gene3D G3DSA:3.60.15.10 1 273 6.3E-88 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L08_07775 041eb4b316d0e7999a4145e08e1508c5 276 Pfam PF00753 Metallo-beta-lactamase superfamily 22 108 5.2E-15 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L08_07775 041eb4b316d0e7999a4145e08e1508c5 276 SMART SM00849 21 245 9.3E-12 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L08_02785 9ebd7b86b9b52e61628d7a758ffbd6b6 271 Pfam PF12706 Beta-lactamase superfamily domain 32 220 7.2E-27 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L08_02785 9ebd7b86b9b52e61628d7a758ffbd6b6 271 Gene3D G3DSA:3.60.15.10 1 253 8.9E-31 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L08_02785 9ebd7b86b9b52e61628d7a758ffbd6b6 271 SUPERFAMILY SSF56281 3 252 1.9E-37 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L08_09550 fe71cb617598d5328e08203fea6dd68e 244 Pfam PF03205 Molybdopterin guanine dinucleotide synthesis protein B 4 111 1.8E-17 T 23-10-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 A3L08_09550 fe71cb617598d5328e08203fea6dd68e 244 Pfam PF04060 Putative Fe-S cluster 160 191 1.2E-8 T 23-10-2018 IPR007202 4Fe-4S domain GO:0051536 A3L08_09550 fe71cb617598d5328e08203fea6dd68e 244 TIGRFAM TIGR00176 mobB: molybdopterin-guanine dinucleotide biosynthesis protein B 5 154 6.7E-23 T 23-10-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 A3L08_09550 fe71cb617598d5328e08203fea6dd68e 244 SUPERFAMILY SSF52540 1 105 9.38E-12 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_09550 fe71cb617598d5328e08203fea6dd68e 244 Gene3D G3DSA:3.40.50.300 1 157 1.4E-28 T 23-10-2018 A3L08_09550 fe71cb617598d5328e08203fea6dd68e 244 Gene3D G3DSA:3.20.20.20 158 220 6.5E-6 T 23-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A3L08_09765 851b119ace5a130a34b523c426dec550 192 Pfam PF04199 Putative cyclase 3 134 2.4E-24 T 23-10-2018 IPR007325 Kynurenine formamidase/cyclase-like GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 A3L08_09765 851b119ace5a130a34b523c426dec550 192 Gene3D G3DSA:3.50.30.50 1 190 1.0E-58 T 23-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 A3L08_09765 851b119ace5a130a34b523c426dec550 192 SUPERFAMILY SSF102198 2 188 1.44E-55 T 23-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 A3L08_02800 4556a9cbb3804706589462b0eadc68f2 372 SUPERFAMILY SSF50331 242 370 5.83E-25 T 23-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal A3L08_02800 4556a9cbb3804706589462b0eadc68f2 372 SMART SM00382 28 217 3.0E-15 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L08_02800 4556a9cbb3804706589462b0eadc68f2 372 Pfam PF00005 ABC transporter 20 167 3.4E-31 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L08_02800 4556a9cbb3804706589462b0eadc68f2 372 Gene3D G3DSA:3.40.50.300 2 243 9.8E-77 T 23-10-2018 A3L08_02800 4556a9cbb3804706589462b0eadc68f2 372 SUPERFAMILY SSF52540 5 249 6.65E-89 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_02800 4556a9cbb3804706589462b0eadc68f2 372 Gene3D G3DSA:2.40.50.100 245 304 1.9E-23 T 23-10-2018 A3L08_02800 4556a9cbb3804706589462b0eadc68f2 372 Pfam PF08402 TOBE domain 288 363 6.9E-6 T 23-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 A3L08_02800 4556a9cbb3804706589462b0eadc68f2 372 Gene3D G3DSA:2.40.50.140 310 354 1.7E-25 T 23-10-2018 A3L08_02800 4556a9cbb3804706589462b0eadc68f2 372 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L08_05960 b12ad343ce51e03f21dfee9dffc2c4da 278 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 137 154 - T 23-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 A3L08_05960 b12ad343ce51e03f21dfee9dffc2c4da 278 Pfam PF00248 Aldo/keto reductase family 21 276 5.6E-62 T 23-10-2018 IPR023210 NADP-dependent oxidoreductase domain A3L08_05960 b12ad343ce51e03f21dfee9dffc2c4da 278 PRINTS PR00069 Aldo-keto reductase signature 105 123 1.1E-18 T 23-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A3L08_05960 b12ad343ce51e03f21dfee9dffc2c4da 278 PRINTS PR00069 Aldo-keto reductase signature 49 73 1.1E-18 T 23-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A3L08_05960 b12ad343ce51e03f21dfee9dffc2c4da 278 PRINTS PR00069 Aldo-keto reductase signature 212 236 1.1E-18 T 23-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A3L08_05960 b12ad343ce51e03f21dfee9dffc2c4da 278 PRINTS PR00069 Aldo-keto reductase signature 137 154 1.1E-18 T 23-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A3L08_05960 b12ad343ce51e03f21dfee9dffc2c4da 278 Gene3D G3DSA:3.20.20.100 11 276 1.3E-88 T 23-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily A3L08_05960 b12ad343ce51e03f21dfee9dffc2c4da 278 SUPERFAMILY SSF51430 16 272 1.96E-76 T 23-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily A3L08_05960 b12ad343ce51e03f21dfee9dffc2c4da 278 PIRSF PIRSF000097 125 276 2.0E-19 T 23-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A3L08_05960 b12ad343ce51e03f21dfee9dffc2c4da 278 PIRSF PIRSF000097 11 129 1.1E-19 T 23-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A3L08_06995 5743d403ef96ff1a7ce8e5c48fc67c65 340 SUPERFAMILY SSF49899 85 338 1.22E-81 T 23-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily A3L08_06995 5743d403ef96ff1a7ce8e5c48fc67c65 340 Pfam PF00722 Glycosyl hydrolases family 16 131 333 2.1E-42 T 23-10-2018 IPR000757 Glycoside hydrolase family 16 GO:0004553|GO:0005975 A3L08_06995 5743d403ef96ff1a7ce8e5c48fc67c65 340 Gene3D G3DSA:2.60.120.200 78 338 1.6E-105 T 23-10-2018 A3L08_08965 b152f513aac028c506c4b5960f36b401 375 Hamap MF_02009 Tyrosine--tRNA ligase [tyrS]. 5 359 47.851 T 23-10-2018 IPR023678 Tyrosine-tRNA ligase, type 4 GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 A3L08_08965 b152f513aac028c506c4b5960f36b401 375 SUPERFAMILY SSF52374 2 363 7.03E-66 T 23-10-2018 A3L08_08965 b152f513aac028c506c4b5960f36b401 375 PIRSF PIRSF006588 1 375 9.7E-130 T 23-10-2018 IPR023617 Tyrosine-tRNA ligase, archaeal/eukaryotic-type GO:0004831 KEGG: 00970+6.1.1.1 A3L08_08965 b152f513aac028c506c4b5960f36b401 375 Gene3D G3DSA:3.40.50.620 1 226 1.8E-59 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L08_08965 b152f513aac028c506c4b5960f36b401 375 Pfam PF00579 tRNA synthetases class I (W and Y) 34 352 2.2E-43 T 23-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L08_08965 b152f513aac028c506c4b5960f36b401 375 Gene3D G3DSA:1.10.240.10 227 375 1.8E-56 T 23-10-2018 A3L08_02120 91b0c89b206e067151166f6197bf4e46 384 SUPERFAMILY SSF52374 4 368 7.29E-91 T 23-10-2018 A3L08_02120 91b0c89b206e067151166f6197bf4e46 384 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 72 381 3.6E-105 T 23-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 A3L08_02120 91b0c89b206e067151166f6197bf4e46 384 Gene3D G3DSA:1.10.240.10 255 367 3.5E-44 T 23-10-2018 A3L08_02120 91b0c89b206e067151166f6197bf4e46 384 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 81 90 - T 23-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L08_02120 91b0c89b206e067151166f6197bf4e46 384 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 208 229 5.3E-20 T 23-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 A3L08_02120 91b0c89b206e067151166f6197bf4e46 384 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 85 101 5.3E-20 T 23-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 A3L08_02120 91b0c89b206e067151166f6197bf4e46 384 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 252 262 5.3E-20 T 23-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 A3L08_02120 91b0c89b206e067151166f6197bf4e46 384 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 138 157 5.3E-20 T 23-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 A3L08_02120 91b0c89b206e067151166f6197bf4e46 384 Gene3D G3DSA:3.40.50.620 1 254 9.7E-103 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L08_02120 91b0c89b206e067151166f6197bf4e46 384 Pfam PF00579 tRNA synthetases class I (W and Y) 73 347 2.6E-25 T 23-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L08_02120 91b0c89b206e067151166f6197bf4e46 384 Hamap MF_00140_A Tryptophan--tRNA ligase [trpS]. 5 366 45.783 T 23-10-2018 IPR020653 Tryptophan-tRNA ligase, archaea GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 A3L08_08485 6f443b4551a92f42626aa9b852b4e28a 138 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 13 113 4.2E-16 T 23-10-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis A3L08_08485 6f443b4551a92f42626aa9b852b4e28a 138 SUPERFAMILY SSF53146 3 116 6.15E-15 T 23-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily A3L08_08485 6f443b4551a92f42626aa9b852b4e28a 138 Gene3D G3DSA:3.30.420.130 2 127 8.5E-15 T 23-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily A3L08_01650 f162f0d5b4034cf792d758ef96e47812 351 Gene3D G3DSA:1.25.40.10 1 351 1.6E-84 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A3L08_01650 f162f0d5b4034cf792d758ef96e47812 351 SUPERFAMILY SSF48452 7 173 7.59E-10 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A3L08_04630 ce2b9937c68b9b70c9e2d3e0ac41843a 241 SUPERFAMILY SSF52768 56 232 1.98E-23 T 23-10-2018 IPR023696 Ureohydrolase domain superfamily A3L08_04630 ce2b9937c68b9b70c9e2d3e0ac41843a 241 Gene3D G3DSA:3.40.800.10 46 241 1.1E-16 T 23-10-2018 A3L08_04630 ce2b9937c68b9b70c9e2d3e0ac41843a 241 Pfam PF00491 Arginase family 56 224 6.3E-16 T 23-10-2018 IPR006035 Ureohydrolase GO:0046872 A3L08_04630 ce2b9937c68b9b70c9e2d3e0ac41843a 241 PIRSF PIRSF036979 36 239 3.9E-13 T 23-10-2018 IPR006035 Ureohydrolase GO:0046872 A3L08_08310 98689df286a7f4c20a998e0bc48062cc 452 Gene3D G3DSA:3.90.550.10 76 304 5.8E-39 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L08_08310 98689df286a7f4c20a998e0bc48062cc 452 Pfam PF00535 Glycosyl transferase family 2 93 235 4.5E-31 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A3L08_08310 98689df286a7f4c20a998e0bc48062cc 452 SUPERFAMILY SSF53448 86 353 2.84E-53 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L08_08090 9412bdf05816cd0d76aba7a662f88a04 300 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 248 3.7E-70 T 23-10-2018 A3L08_08090 9412bdf05816cd0d76aba7a662f88a04 300 SUPERFAMILY SSF51735 6 248 3.76E-84 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L08_08090 9412bdf05816cd0d76aba7a662f88a04 300 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 7.4E-43 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L08_08090 9412bdf05816cd0d76aba7a662f88a04 300 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 7.4E-43 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L08_08090 9412bdf05816cd0d76aba7a662f88a04 300 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 231 7.4E-43 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L08_08090 9412bdf05816cd0d76aba7a662f88a04 300 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 7.4E-43 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L08_08090 9412bdf05816cd0d76aba7a662f88a04 300 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 7.4E-43 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L08_08090 9412bdf05816cd0d76aba7a662f88a04 300 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 7.4E-43 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L08_08090 9412bdf05816cd0d76aba7a662f88a04 300 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 23-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A3L08_08090 9412bdf05816cd0d76aba7a662f88a04 300 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 3.1E-14 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L08_08090 9412bdf05816cd0d76aba7a662f88a04 300 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 3.1E-14 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L08_08090 9412bdf05816cd0d76aba7a662f88a04 300 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 3.1E-14 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L08_08090 9412bdf05816cd0d76aba7a662f88a04 300 Gene3D G3DSA:3.40.50.720 1 272 5.3E-85 T 23-10-2018 A3L08_06685 abe448d1d8f4a5756cf1b6aa2ce0f95c 389 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 230 243 - T 23-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 A3L08_06685 abe448d1d8f4a5756cf1b6aa2ce0f95c 389 Pfam PF00155 Aminotransferase class I and II 27 378 2.4E-80 T 23-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A3L08_06685 abe448d1d8f4a5756cf1b6aa2ce0f95c 389 Gene3D G3DSA:3.90.1150.10 27 378 2.5E-154 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A3L08_06685 abe448d1d8f4a5756cf1b6aa2ce0f95c 389 SUPERFAMILY SSF53383 2 385 1.09E-126 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A3L08_06685 abe448d1d8f4a5756cf1b6aa2ce0f95c 389 Gene3D G3DSA:3.40.640.10 58 280 2.5E-154 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A3L08_03680 67e095b7f0bb38d21a4ad1b8c3e418bf 281 Pfam PF01261 Xylose isomerase-like TIM barrel 28 239 7.3E-21 T 23-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain A3L08_03680 67e095b7f0bb38d21a4ad1b8c3e418bf 281 SUPERFAMILY SSF51658 7 279 9.76E-63 T 23-10-2018 IPR036237 Xylose isomerase-like superfamily A3L08_03680 67e095b7f0bb38d21a4ad1b8c3e418bf 281 Gene3D G3DSA:3.20.20.150 13 281 1.1E-42 T 23-10-2018 A3L08_03680 67e095b7f0bb38d21a4ad1b8c3e418bf 281 SMART SM00518 4 276 1.7E-90 T 23-10-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 A3L08_08160 7b263a3f40180506f3ed47b89cd70142 458 Pfam PF01554 MatE 26 186 1.5E-38 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A3L08_08160 7b263a3f40180506f3ed47b89cd70142 458 Pfam PF01554 MatE 248 413 5.2E-25 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A3L08_08160 7b263a3f40180506f3ed47b89cd70142 458 TIGRFAM TIGR00797 matE: MATE efflux family protein 26 426 1.2E-82 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A3L08_08160 7b263a3f40180506f3ed47b89cd70142 458 PIRSF PIRSF006603 4 457 1.6E-100 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A3L08_00065 8a1ce706475493d71d3a6cfbd7e17708 67 Hamap MF_00511 30S ribosomal protein S17e [rps17e]. 1 63 22.031 T 23-10-2018 IPR001210 Ribosomal protein S17e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_00065 8a1ce706475493d71d3a6cfbd7e17708 67 SUPERFAMILY SSF116820 1 60 1.96E-23 T 23-10-2018 IPR036401 Ribosomal protein S17e-like superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_00065 8a1ce706475493d71d3a6cfbd7e17708 67 Pfam PF00833 Ribosomal S17 1 64 2.6E-15 T 23-10-2018 IPR001210 Ribosomal protein S17e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_00065 8a1ce706475493d71d3a6cfbd7e17708 67 Gene3D G3DSA:1.10.60.20 1 62 3.0E-29 T 23-10-2018 IPR036401 Ribosomal protein S17e-like superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_00065 8a1ce706475493d71d3a6cfbd7e17708 67 ProSitePatterns PS00712 Ribosomal protein S17e signature. 41 56 - T 23-10-2018 IPR018273 Ribosomal protein S17e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_08830 298c43151210cc5bb1d31ed49dae4293 631 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 607 618 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L08_08830 298c43151210cc5bb1d31ed49dae4293 631 SMART SM00359 133 207 3.8E-17 T 23-10-2018 IPR002478 PUA domain GO:0003723 A3L08_08830 298c43151210cc5bb1d31ed49dae4293 631 Gene3D G3DSA:2.30.130.10 130 207 1.2E-14 T 23-10-2018 IPR036974 PUA domain superfamily GO:0003723 A3L08_08830 298c43151210cc5bb1d31ed49dae4293 631 TIGRFAM TIGR00451 unchar_dom_2: uncharacterized domain 2 95 203 1.1E-10 T 23-10-2018 IPR004521 Uncharacterised domain CHP00451 GO:0003723 A3L08_08830 298c43151210cc5bb1d31ed49dae4293 631 SUPERFAMILY SSF52402 223 416 1.4E-43 T 23-10-2018 A3L08_08830 298c43151210cc5bb1d31ed49dae4293 631 Gene3D G3DSA:3.40.50.620 212 479 2.9E-49 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L08_08830 298c43151210cc5bb1d31ed49dae4293 631 SUPERFAMILY SSF88697 132 204 7.73E-16 T 23-10-2018 IPR015947 PUA-like superfamily A3L08_08830 298c43151210cc5bb1d31ed49dae4293 631 SUPERFAMILY SSF54862 570 623 2.82E-15 T 23-10-2018 A3L08_08830 298c43151210cc5bb1d31ed49dae4293 631 Pfam PF01472 PUA domain 134 204 2.4E-15 T 23-10-2018 IPR002478 PUA domain GO:0003723 A3L08_08830 298c43151210cc5bb1d31ed49dae4293 631 Pfam PF12838 4Fe-4S dicluster domain 576 618 3.9E-9 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L08_08830 298c43151210cc5bb1d31ed49dae4293 631 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 576 587 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L08_08830 298c43151210cc5bb1d31ed49dae4293 631 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 252 430 5.2E-43 T 23-10-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824 Reactome: R-HSA-196843 A3L08_08830 298c43151210cc5bb1d31ed49dae4293 631 Gene3D G3DSA:3.30.70.20 572 622 8.7E-11 T 23-10-2018 A3L08_01955 6ba598b47f1f7f6f26dd2555db0feb52 385 Pfam PF17125 N-terminal domain of 16S rRNA methyltransferase RsmF 8 78 4.2E-7 T 23-10-2018 IPR031341 Ribosomal RNA small subunit methyltransferase F, N-terminal Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 A3L08_01955 6ba598b47f1f7f6f26dd2555db0feb52 385 Pfam PF01189 16S rRNA methyltransferase RsmB/F 192 381 1.3E-56 T 23-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 A3L08_01955 6ba598b47f1f7f6f26dd2555db0feb52 385 TIGRFAM TIGR00446 nop2p: NOL1/NOP2/sun family putative RNA methylase 168 382 1.7E-63 T 23-10-2018 IPR011023 Nop2p GO:0003723|GO:0006364|GO:0008757 Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 A3L08_01955 6ba598b47f1f7f6f26dd2555db0feb52 385 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 203 213 6.9E-25 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L08_01955 6ba598b47f1f7f6f26dd2555db0feb52 385 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 174 188 6.9E-25 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L08_01955 6ba598b47f1f7f6f26dd2555db0feb52 385 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 316 332 6.9E-25 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L08_01955 6ba598b47f1f7f6f26dd2555db0feb52 385 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 269 281 6.9E-25 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L08_01955 6ba598b47f1f7f6f26dd2555db0feb52 385 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 365 382 6.9E-25 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A3L08_01955 6ba598b47f1f7f6f26dd2555db0feb52 385 Gene3D G3DSA:3.40.50.150 188 385 9.5E-61 T 23-10-2018 A3L08_01955 6ba598b47f1f7f6f26dd2555db0feb52 385 SUPERFAMILY SSF53335 4 383 4.06E-55 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L08_01955 6ba598b47f1f7f6f26dd2555db0feb52 385 SMART SM00359 90 164 4.8E-19 T 23-10-2018 IPR002478 PUA domain GO:0003723 A3L08_01955 6ba598b47f1f7f6f26dd2555db0feb52 385 Gene3D G3DSA:3.30.70.3130 2 83 7.4E-13 T 23-10-2018 A3L08_01955 6ba598b47f1f7f6f26dd2555db0feb52 385 Pfam PF01472 PUA domain 93 159 3.3E-16 T 23-10-2018 IPR002478 PUA domain GO:0003723 A3L08_01955 6ba598b47f1f7f6f26dd2555db0feb52 385 Gene3D G3DSA:2.30.130.70 84 163 6.9E-15 T 23-10-2018 A3L08_01955 6ba598b47f1f7f6f26dd2555db0feb52 385 SUPERFAMILY SSF88697 89 160 1.49E-16 T 23-10-2018 IPR015947 PUA-like superfamily A3L08_03260 58cffe041e07881b3aa198e5091cdbaf 380 Pfam PF06849 Protein of unknown function (DUF1246) 21 154 3.0E-42 T 23-10-2018 IPR010672 IMP biosynthesis enzyme PurP, N-terminal GO:0000287|GO:0005524|GO:0006188|GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 A3L08_03260 58cffe041e07881b3aa198e5091cdbaf 380 SUPERFAMILY SSF52440 1 133 7.39E-41 T 23-10-2018 IPR016185 Pre-ATP-grasp domain superfamily A3L08_03260 58cffe041e07881b3aa198e5091cdbaf 380 Pfam PF06973 Domain of unknown function (DUF1297) 189 380 6.3E-80 T 23-10-2018 IPR009720 IMP biosynthesis enzyme PurP, C-terminal GO:0000287|GO:0005524|GO:0006188|GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 A3L08_03260 58cffe041e07881b3aa198e5091cdbaf 380 Gene3D G3DSA:3.30.1490.20 152 218 7.7E-93 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 A3L08_03260 58cffe041e07881b3aa198e5091cdbaf 380 SUPERFAMILY SSF56059 139 380 9.96E-76 T 23-10-2018 A3L08_03260 58cffe041e07881b3aa198e5091cdbaf 380 PIRSF PIRSF004602 1 380 1.5E-141 T 23-10-2018 IPR023656 IMP biosynthesis enzyme PurP GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 A3L08_03260 58cffe041e07881b3aa198e5091cdbaf 380 Gene3D G3DSA:3.30.470.20 122 379 7.7E-93 T 23-10-2018 A3L08_03260 58cffe041e07881b3aa198e5091cdbaf 380 Gene3D G3DSA:3.40.50.20 1 121 2.2E-42 T 23-10-2018 A3L08_04535 03ae76d12ac3253362ae114e21728603 203 Hamap MF_02113_A Proteasome subunit beta [prcB]. 3 197 35.535 T 23-10-2018 IPR019983 Peptidase T1A, proteasome beta-subunit, archaeal GO:0004175|GO:0005839|GO:0051603 A3L08_04535 03ae76d12ac3253362ae114e21728603 203 TIGRFAM TIGR03634 arc_protsome_B: proteasome endopeptidase complex, archaeal, beta subunit 7 190 4.9E-76 T 23-10-2018 IPR019983 Peptidase T1A, proteasome beta-subunit, archaeal GO:0004175|GO:0005839|GO:0051603 A3L08_04535 03ae76d12ac3253362ae114e21728603 203 Gene3D G3DSA:3.60.20.10 3 203 8.2E-66 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A3L08_04535 03ae76d12ac3253362ae114e21728603 203 ProSitePatterns PS00854 Proteasome beta-type subunits signature. 11 58 - T 23-10-2018 IPR016050 Proteasome beta-type subunit, conserved site GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 A3L08_04535 03ae76d12ac3253362ae114e21728603 203 PRINTS PR00141 Proteasome component signature 15 30 1.8E-9 T 23-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 A3L08_04535 03ae76d12ac3253362ae114e21728603 203 PRINTS PR00141 Proteasome component signature 171 182 1.8E-9 T 23-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 A3L08_04535 03ae76d12ac3253362ae114e21728603 203 PRINTS PR00141 Proteasome component signature 135 146 1.8E-9 T 23-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 A3L08_04535 03ae76d12ac3253362ae114e21728603 203 PRINTS PR00141 Proteasome component signature 146 157 1.8E-9 T 23-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 A3L08_04535 03ae76d12ac3253362ae114e21728603 203 Pfam PF00227 Proteasome subunit 6 185 1.0E-51 T 23-10-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 A3L08_04535 03ae76d12ac3253362ae114e21728603 203 SUPERFAMILY SSF56235 5 202 8.14E-62 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A3L08_05055 61a95619088764cd4f8d0d8c2baae56a 145 SUPERFAMILY SSF54814 13 74 1.18E-11 T 23-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 A3L08_05055 61a95619088764cd4f8d0d8c2baae56a 145 SMART SM00322 32 115 0.0032 T 23-10-2018 IPR004087 K Homology domain GO:0003676 A3L08_05055 61a95619088764cd4f8d0d8c2baae56a 145 Hamap MF_00945_A Transcription termination/antitermination protein NusA [nusA]. 1 145 30.1 T 23-10-2018 IPR010212 Probable transcription termination protein NusA, archaeal A3L08_05055 61a95619088764cd4f8d0d8c2baae56a 145 TIGRFAM TIGR01952 nusA_arch: NusA family KH domain protein, archaeal 1 145 2.3E-59 T 23-10-2018 IPR010212 Probable transcription termination protein NusA, archaeal A3L08_05055 61a95619088764cd4f8d0d8c2baae56a 145 Gene3D G3DSA:3.30.300.20 74 144 9.0E-23 T 23-10-2018 IPR015946 K homology domain-like, alpha/beta A3L08_05055 61a95619088764cd4f8d0d8c2baae56a 145 Pfam PF07650 KH domain 14 94 4.2E-17 T 23-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_05055 61a95619088764cd4f8d0d8c2baae56a 145 SUPERFAMILY SSF54814 88 141 3.92E-7 T 23-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 A3L08_05055 61a95619088764cd4f8d0d8c2baae56a 145 Gene3D G3DSA:3.30.300.20 2 73 4.5E-27 T 23-10-2018 IPR015946 K homology domain-like, alpha/beta A3L08_06490 b778ea9589fa1dd51375ac506e8eee5e 295 Gene3D G3DSA:2.40.30.10 17 115 4.6E-19 T 23-10-2018 A3L08_06490 b778ea9589fa1dd51375ac506e8eee5e 295 SUPERFAMILY SSF52343 111 286 1.57E-31 T 23-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A3L08_06490 b778ea9589fa1dd51375ac506e8eee5e 295 Gene3D G3DSA:2.10.240.10 252 288 9.5E-8 T 23-10-2018 IPR037117 Dihydroorotate dehydrogenase, electron transfer subunit, Fe-S binding domain superfamily A3L08_06490 b778ea9589fa1dd51375ac506e8eee5e 295 Pfam PF00175 Oxidoreductase NAD-binding domain 128 232 4.0E-12 T 23-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 A3L08_06490 b778ea9589fa1dd51375ac506e8eee5e 295 PRINTS PR00410 Phenol hydroxylase reductase family signature 53 65 1.4E-7 T 23-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 A3L08_06490 b778ea9589fa1dd51375ac506e8eee5e 295 PRINTS PR00410 Phenol hydroxylase reductase family signature 127 146 1.4E-7 T 23-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 A3L08_06490 b778ea9589fa1dd51375ac506e8eee5e 295 PRINTS PR00410 Phenol hydroxylase reductase family signature 219 227 1.4E-7 T 23-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 A3L08_06490 b778ea9589fa1dd51375ac506e8eee5e 295 SUPERFAMILY SSF63380 16 119 9.85E-24 T 23-10-2018 IPR017938 Riboflavin synthase-like beta-barrel A3L08_06490 b778ea9589fa1dd51375ac506e8eee5e 295 Pfam PF00970 Oxidoreductase FAD-binding domain 38 114 4.2E-8 T 23-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 A3L08_06490 b778ea9589fa1dd51375ac506e8eee5e 295 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 251 287 9.1E-13 T 23-10-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain A3L08_06490 b778ea9589fa1dd51375ac506e8eee5e 295 PIRSF PIRSF006816 17 294 6.5E-83 T 23-10-2018 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 A3L08_06490 b778ea9589fa1dd51375ac506e8eee5e 295 Gene3D G3DSA:3.40.50.80 120 251 2.0E-22 T 23-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A3L08_00085 4b3c0ce91d90ee9f022a9258edc9d354 67 SMART SM00803 12 66 0.0036 T 23-10-2018 IPR004823 TATA box binding protein associated factor (TAF) GO:0006352 A3L08_00085 4b3c0ce91d90ee9f022a9258edc9d354 67 Pfam PF00808 Histone-like transcription factor (CBF/NF-Y) and archaeal histone 2 65 2.3E-21 T 23-10-2018 IPR003958 Transcription factor CBF/NF-Y/archaeal histone domain A3L08_00085 4b3c0ce91d90ee9f022a9258edc9d354 67 Gene3D G3DSA:1.10.20.10 1 67 1.5E-22 T 23-10-2018 IPR009072 Histone-fold GO:0046982 A3L08_00085 4b3c0ce91d90ee9f022a9258edc9d354 67 SUPERFAMILY SSF47113 3 66 4.92E-20 T 23-10-2018 IPR009072 Histone-fold GO:0046982 A3L08_06950 a0810795cb47d7f0a1e9b5e29c998e50 282 Gene3D G3DSA:1.10.3720.10 63 280 3.8E-10 T 23-10-2018 IPR035906 MetI-like superfamily A3L08_06950 a0810795cb47d7f0a1e9b5e29c998e50 282 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 92 280 2.8E-16 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A3L08_06950 a0810795cb47d7f0a1e9b5e29c998e50 282 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 3 44 1.8E-7 T 23-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain A3L08_06950 a0810795cb47d7f0a1e9b5e29c998e50 282 SUPERFAMILY SSF161098 71 260 8.5E-14 T 23-10-2018 IPR035906 MetI-like superfamily A3L08_00835 a22084c5f20bbdc6a215bbd1eba6ef09 398 Hamap MF_00553 Proteasome-activating nucleotidase [pan]. 2 397 47.637 T 23-10-2018 IPR023501 Proteasome-activating nucleotidase PAN A3L08_00835 a22084c5f20bbdc6a215bbd1eba6ef09 398 Pfam PF16450 Proteasomal ATPase OB/ID domain 65 122 3.3E-7 T 23-10-2018 IPR032501 Proteasomal ATPase, OB/ID domain A3L08_00835 a22084c5f20bbdc6a215bbd1eba6ef09 398 Gene3D G3DSA:1.10.8.60 310 381 3.4E-30 T 23-10-2018 A3L08_00835 a22084c5f20bbdc6a215bbd1eba6ef09 398 ProSitePatterns PS00674 AAA-protein family signature. 279 297 - T 23-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 A3L08_00835 a22084c5f20bbdc6a215bbd1eba6ef09 398 SMART SM00382 172 311 1.0E-23 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L08_00835 a22084c5f20bbdc6a215bbd1eba6ef09 398 TIGRFAM TIGR01242 26Sp45: 26S proteasome subunit P45 family 19 380 2.5E-199 T 23-10-2018 IPR005937 26S proteasome regulatory subunit P45-like GO:0005737|GO:0016787|GO:0030163 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 A3L08_00835 a22084c5f20bbdc6a215bbd1eba6ef09 398 Gene3D G3DSA:2.40.50.140 25 128 2.4E-26 T 23-10-2018 A3L08_00835 a22084c5f20bbdc6a215bbd1eba6ef09 398 SUPERFAMILY SSF52540 134 382 4.28E-72 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_00835 a22084c5f20bbdc6a215bbd1eba6ef09 398 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 176 309 1.4E-43 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A3L08_00835 a22084c5f20bbdc6a215bbd1eba6ef09 398 Gene3D G3DSA:3.40.50.300 129 309 7.3E-71 T 23-10-2018 A3L08_07325 10e7e4b9260bac4852f78708bea6702d 257 Gene3D G3DSA:1.10.510.10 156 255 1.1E-24 T 23-10-2018 A3L08_07325 10e7e4b9260bac4852f78708bea6702d 257 SUPERFAMILY SSF56112 55 238 5.22E-21 T 23-10-2018 IPR011009 Protein kinase-like domain superfamily A3L08_07325 10e7e4b9260bac4852f78708bea6702d 257 Gene3D G3DSA:3.30.200.20 51 151 2.9E-13 T 23-10-2018 A3L08_07325 10e7e4b9260bac4852f78708bea6702d 257 SMART SM00090 23 257 3.1E-116 T 23-10-2018 IPR000687 RIO kinase GO:0004674|GO:0005524 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6791226 A3L08_07325 10e7e4b9260bac4852f78708bea6702d 257 ProSitePatterns PS01245 RIO1/ZK632.3/MJ0444 family signature. 191 202 - T 23-10-2018 IPR018935 RIO kinase, conserved site GO:0004674|GO:0005524 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6791226 A3L08_07325 10e7e4b9260bac4852f78708bea6702d 257 Pfam PF01163 RIO1 family 65 247 5.9E-54 T 23-10-2018 A3L08_07975 5b11a0c0f43d27ae2434c3d2c3dbe2dc 409 PIRSF PIRSF005243 4 408 1.4E-112 T 23-10-2018 IPR016440 Rubredoxin-oxygen oxidoreductase GO:0009055|GO:0010181|GO:0016491|GO:0046872 A3L08_07975 5b11a0c0f43d27ae2434c3d2c3dbe2dc 409 Gene3D G3DSA:3.60.15.10 1 258 7.7E-88 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L08_07975 5b11a0c0f43d27ae2434c3d2c3dbe2dc 409 Pfam PF00753 Metallo-beta-lactamase superfamily 41 185 2.9E-6 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L08_07975 5b11a0c0f43d27ae2434c3d2c3dbe2dc 409 Gene3D G3DSA:3.40.50.360 259 404 1.1E-28 T 23-10-2018 IPR029039 Flavoprotein-like superfamily A3L08_07975 5b11a0c0f43d27ae2434c3d2c3dbe2dc 409 SUPERFAMILY SSF56281 9 255 1.18E-43 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L08_07975 5b11a0c0f43d27ae2434c3d2c3dbe2dc 409 SUPERFAMILY SSF52218 261 408 2.1E-30 T 23-10-2018 IPR029039 Flavoprotein-like superfamily A3L08_07975 5b11a0c0f43d27ae2434c3d2c3dbe2dc 409 SMART SM00849 39 209 2.0E-24 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L08_05145 5f269ff0dc6c17941d65608db27150ec 59 Pfam PF04135 Nucleolar RNA-binding protein, Nop10p family 1 51 1.1E-27 T 23-10-2018 IPR007264 H/ACA ribonucleoprotein complex, subunit Nop10 GO:0001522|GO:0030515|GO:0042254 Reactome: R-HSA-6790901 A3L08_05145 5f269ff0dc6c17941d65608db27150ec 59 Gene3D G3DSA:2.20.28.40 1 59 1.1E-30 T 23-10-2018 IPR036756 H/ACA ribonucleoprotein complex, subunit Nop10 superfamily GO:0001522|GO:0030515|GO:0042254 Reactome: R-HSA-6790901 A3L08_05145 5f269ff0dc6c17941d65608db27150ec 59 SUPERFAMILY SSF144210 4 51 3.79E-22 T 23-10-2018 IPR036756 H/ACA ribonucleoprotein complex, subunit Nop10 superfamily GO:0001522|GO:0030515|GO:0042254 Reactome: R-HSA-6790901 A3L08_05145 5f269ff0dc6c17941d65608db27150ec 59 Hamap MF_00803 Ribosome biogenesis protein Nop10 [nop10]. 3 53 21.346 T 23-10-2018 IPR023532 H/ACA ribonucleoprotein complex subunit Nop10 , archaeal-type GO:0001522|GO:0030515|GO:0042254 A3L08_05910 65daa8bf0b386a01bd489fa1e2059eb6 213 Gene3D G3DSA:3.90.1490.10 117 209 5.0E-12 T 23-10-2018 A3L08_05910 65daa8bf0b386a01bd489fa1e2059eb6 213 SUPERFAMILY SSF52402 2 208 4.65E-50 T 23-10-2018 A3L08_05910 65daa8bf0b386a01bd489fa1e2059eb6 213 TIGRFAM TIGR00290 MJ0570_dom: MJ0570-related uncharacterized domain 2 207 1.2E-34 T 23-10-2018 IPR002761 Diphthamide synthase domain MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 A3L08_05910 65daa8bf0b386a01bd489fa1e2059eb6 213 Pfam PF01902 Diphthamide synthase 2 206 4.1E-35 T 23-10-2018 IPR002761 Diphthamide synthase domain MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 A3L08_05910 65daa8bf0b386a01bd489fa1e2059eb6 213 Gene3D G3DSA:3.40.50.620 1 116 1.3E-15 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L08_03045 53a29ebd7ff04820ed4cd7d603cfc6f9 166 Gene3D G3DSA:2.60.120.10 3 166 2.5E-70 T 23-10-2018 IPR014710 RmlC-like jelly roll fold A3L08_03045 53a29ebd7ff04820ed4cd7d603cfc6f9 166 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 8 166 2.8E-72 T 23-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 A3L08_03045 53a29ebd7ff04820ed4cd7d603cfc6f9 166 SUPERFAMILY SSF51182 3 165 1.13E-73 T 23-10-2018 IPR011051 RmlC-like cupin domain superfamily A3L08_03045 53a29ebd7ff04820ed4cd7d603cfc6f9 166 TIGRFAM TIGR01221 rmlC: dTDP-4-dehydrorhamnose 3,5-epimerase 5 163 1.6E-82 T 23-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 A3L08_03045 53a29ebd7ff04820ed4cd7d603cfc6f9 166 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 3 166 2.0E-83 T 23-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 A3L08_04640 4793451ec89152e87eaf67760e3a999b 70 SUPERFAMILY SSF46785 4 51 8.25E-10 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L08_04640 4793451ec89152e87eaf67760e3a999b 70 Pfam PF09339 IclR helix-turn-helix domain 4 45 1.0E-5 T 23-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 A3L08_04640 4793451ec89152e87eaf67760e3a999b 70 Gene3D G3DSA:1.10.10.10 1 70 1.0E-8 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L08_00645 d9a98ca51eeeac351641a8e6ea01d152 412 PRINTS PR01035 Tetracycline resistance protein signature 38 54 8.2E-7 T 23-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A3L08_00645 d9a98ca51eeeac351641a8e6ea01d152 412 PRINTS PR01035 Tetracycline resistance protein signature 301 322 8.2E-7 T 23-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A3L08_00645 d9a98ca51eeeac351641a8e6ea01d152 412 PRINTS PR01035 Tetracycline resistance protein signature 362 385 8.2E-7 T 23-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A3L08_00645 d9a98ca51eeeac351641a8e6ea01d152 412 PRINTS PR01035 Tetracycline resistance protein signature 152 174 8.2E-7 T 23-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A3L08_00645 d9a98ca51eeeac351641a8e6ea01d152 412 SUPERFAMILY SSF103473 25 410 9.55E-58 T 23-10-2018 IPR036259 MFS transporter superfamily A3L08_00645 d9a98ca51eeeac351641a8e6ea01d152 412 Gene3D G3DSA:1.20.1250.20 20 240 1.4E-32 T 23-10-2018 A3L08_00645 d9a98ca51eeeac351641a8e6ea01d152 412 Gene3D G3DSA:1.20.1250.20 241 412 2.0E-26 T 23-10-2018 A3L08_00645 d9a98ca51eeeac351641a8e6ea01d152 412 Pfam PF07690 Major Facilitator Superfamily 32 270 3.5E-26 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A3L08_09470 5e09203cddacaf1b1d542f944ff82258 253 SUPERFAMILY SSF54001 33 191 1.0E-9 T 23-10-2018 IPR038765 Papain-like cysteine peptidase superfamily A3L08_09470 5e09203cddacaf1b1d542f944ff82258 253 Gene3D G3DSA:3.10.620.30 76 198 2.1E-6 T 23-10-2018 A3L08_09470 5e09203cddacaf1b1d542f944ff82258 253 Pfam PF04473 Transglutaminase-like domain 87 201 2.9E-20 T 23-10-2018 IPR007562 Transglutaminase-like domain A3L08_00120 3d6634bbe4b7e8c0fbb9521c5eaf5e89 487 Pfam PF09847 Membrane protein of 12 TMs 40 480 5.3E-78 T 23-10-2018 IPR018646 Membrane protein of 12 TMs A3L08_00120 3d6634bbe4b7e8c0fbb9521c5eaf5e89 487 PIRSF PIRSF018875 1 486 3.1E-82 T 23-10-2018 IPR018646 Membrane protein of 12 TMs A3L08_03505 a0da4c2284b7026de26470901c9c454b 342 Gene3D G3DSA:3.40.50.11860 212 313 9.8E-35 T 23-10-2018 A3L08_03505 a0da4c2284b7026de26470901c9c454b 342 Gene3D G3DSA:3.40.50.11850 100 208 1.9E-40 T 23-10-2018 A3L08_03505 a0da4c2284b7026de26470901c9c454b 342 TIGRFAM TIGR00322 diphth2_R: diphthamide biosynthesis enzyme Dph1/Dph2 domain 4 313 7.6E-91 T 23-10-2018 IPR016435 Diphthamide synthesis DPH1/DPH2 MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 A3L08_03505 a0da4c2284b7026de26470901c9c454b 342 Gene3D G3DSA:3.40.50.11840 5 98 7.8E-29 T 23-10-2018 A3L08_03505 a0da4c2284b7026de26470901c9c454b 342 Pfam PF01866 Putative diphthamide synthesis protein 26 317 6.9E-77 T 23-10-2018 IPR016435 Diphthamide synthesis DPH1/DPH2 MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 A3L08_03505 a0da4c2284b7026de26470901c9c454b 342 PIRSF PIRSF004967 1 335 1.7E-80 T 23-10-2018 IPR035435 Diphthamide synthesis DHP1/DPH2, eukaryotes and archaea GO:0017183 MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 A3L08_03505 a0da4c2284b7026de26470901c9c454b 342 TIGRFAM TIGR03682 arCOG04112: diphthamide biosynthesis enzyme Dph2 18 324 6.3E-112 T 23-10-2018 IPR022428 Diphthamide synthesis Dph2, archaea GO:0017183 MetaCyc: PWY-6482|MetaCyc: PWY-7546 A3L08_08560 28954b616079e4998e2f7fcbbd870c48 118 Gene3D G3DSA:1.10.10.10 47 96 3.2E-11 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L08_08560 28954b616079e4998e2f7fcbbd870c48 118 Pfam PF02001 Protein of unknown function DUF134 13 102 1.4E-26 T 23-10-2018 IPR002852 Uncharacterised protein family UPF0251 A3L08_08560 28954b616079e4998e2f7fcbbd870c48 118 SUPERFAMILY SSF88659 48 93 5.23E-9 T 23-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A3L08_08560 28954b616079e4998e2f7fcbbd870c48 118 Hamap MF_00674 UPF0251 protein . 14 111 23.751 T 23-10-2018 IPR002852 Uncharacterised protein family UPF0251 A3L08_09445 7f15f85804c72a88e5dc862fbb496154 153 Pfam PF06146 Phosphate-starvation-inducible E 63 129 5.2E-17 T 23-10-2018 IPR020948 Phosphate-starvation-induced PsiE-like A3L08_04035 29cbe574d0b530b095481512722dac72 380 Gene3D G3DSA:2.20.25.320 7 67 2.4E-21 T 23-10-2018 A3L08_04035 29cbe574d0b530b095481512722dac72 380 Gene3D G3DSA:3.30.70.3360 314 362 6.5E-38 T 23-10-2018 A3L08_04035 29cbe574d0b530b095481512722dac72 380 Gene3D G3DSA:3.30.1490.70 70 241 2.7E-70 T 23-10-2018 A3L08_04035 29cbe574d0b530b095481512722dac72 380 Pfam PF09414 RNA ligase 86 240 1.5E-17 T 23-10-2018 IPR021122 RNA ligase domain, REL/Rln2 A3L08_04035 29cbe574d0b530b095481512722dac72 380 TIGRFAM TIGR01209 TIGR01209: RNA ligase, Pab1020 family 12 380 2.1E-145 T 23-10-2018 IPR001072 RNA ligase, Pab1020 family A3L08_04035 29cbe574d0b530b095481512722dac72 380 PRINTS PR01048 Hypothetical protein Y414 family signature 260 278 4.0E-55 T 23-10-2018 IPR001072 RNA ligase, Pab1020 family A3L08_04035 29cbe574d0b530b095481512722dac72 380 PRINTS PR01048 Hypothetical protein Y414 family signature 87 100 4.0E-55 T 23-10-2018 IPR001072 RNA ligase, Pab1020 family A3L08_04035 29cbe574d0b530b095481512722dac72 380 PRINTS PR01048 Hypothetical protein Y414 family signature 164 185 4.0E-55 T 23-10-2018 IPR001072 RNA ligase, Pab1020 family A3L08_04035 29cbe574d0b530b095481512722dac72 380 PRINTS PR01048 Hypothetical protein Y414 family signature 108 123 4.0E-55 T 23-10-2018 IPR001072 RNA ligase, Pab1020 family A3L08_04035 29cbe574d0b530b095481512722dac72 380 PRINTS PR01048 Hypothetical protein Y414 family signature 138 153 4.0E-55 T 23-10-2018 IPR001072 RNA ligase, Pab1020 family A3L08_04035 29cbe574d0b530b095481512722dac72 380 PRINTS PR01048 Hypothetical protein Y414 family signature 64 82 4.0E-55 T 23-10-2018 IPR001072 RNA ligase, Pab1020 family A3L08_04035 29cbe574d0b530b095481512722dac72 380 PRINTS PR01048 Hypothetical protein Y414 family signature 219 232 4.0E-55 T 23-10-2018 IPR001072 RNA ligase, Pab1020 family A3L08_04035 29cbe574d0b530b095481512722dac72 380 PRINTS PR01048 Hypothetical protein Y414 family signature 355 375 4.0E-55 T 23-10-2018 IPR001072 RNA ligase, Pab1020 family A3L08_04035 29cbe574d0b530b095481512722dac72 380 PRINTS PR01048 Hypothetical protein Y414 family signature 42 56 4.0E-55 T 23-10-2018 IPR001072 RNA ligase, Pab1020 family A3L08_04035 29cbe574d0b530b095481512722dac72 380 PRINTS PR01048 Hypothetical protein Y414 family signature 291 305 4.0E-55 T 23-10-2018 IPR001072 RNA ligase, Pab1020 family A3L08_04035 29cbe574d0b530b095481512722dac72 380 Gene3D G3DSA:3.30.70.3350 244 374 6.5E-38 T 23-10-2018 A3L08_04035 29cbe574d0b530b095481512722dac72 380 Gene3D G3DSA:3.30.470.30 96 197 2.7E-70 T 23-10-2018 A3L08_04035 29cbe574d0b530b095481512722dac72 380 SUPERFAMILY SSF56091 64 236 5.44E-38 T 23-10-2018 A3L08_05500 276a090ea0f9e7c075202fa2954e7be7 391 SMART SM00116 75 123 0.0089 T 23-10-2018 IPR000644 CBS domain A3L08_05500 276a090ea0f9e7c075202fa2954e7be7 391 SMART SM00116 217 265 5.3E-9 T 23-10-2018 IPR000644 CBS domain A3L08_05500 276a090ea0f9e7c075202fa2954e7be7 391 SMART SM00116 139 187 2.7E-10 T 23-10-2018 IPR000644 CBS domain A3L08_05500 276a090ea0f9e7c075202fa2954e7be7 391 SUPERFAMILY SSF54631 126 261 6.54E-34 T 23-10-2018 A3L08_05500 276a090ea0f9e7c075202fa2954e7be7 391 Pfam PF00571 CBS domain 211 261 3.3E-12 T 23-10-2018 IPR000644 CBS domain A3L08_05500 276a090ea0f9e7c075202fa2954e7be7 391 Pfam PF00571 CBS domain 69 122 8.5E-6 T 23-10-2018 IPR000644 CBS domain A3L08_05500 276a090ea0f9e7c075202fa2954e7be7 391 Pfam PF00571 CBS domain 6 54 0.0069 T 23-10-2018 IPR000644 CBS domain A3L08_05500 276a090ea0f9e7c075202fa2954e7be7 391 Pfam PF00571 CBS domain 133 183 2.9E-16 T 23-10-2018 IPR000644 CBS domain A3L08_05500 276a090ea0f9e7c075202fa2954e7be7 391 SUPERFAMILY SSF54631 4 122 4.04E-18 T 23-10-2018 A3L08_05500 276a090ea0f9e7c075202fa2954e7be7 391 PIRSF PIRSF036983 2 391 1.8E-141 T 23-10-2018 IPR014651 Uncharacterised conserved protein, 2xCBS, MJ1404 type A3L08_05500 276a090ea0f9e7c075202fa2954e7be7 391 Gene3D G3DSA:3.10.580.10 127 206 1.6E-17 T 23-10-2018 A3L08_05500 276a090ea0f9e7c075202fa2954e7be7 391 Gene3D G3DSA:3.10.580.10 207 300 8.2E-16 T 23-10-2018 A3L08_05500 276a090ea0f9e7c075202fa2954e7be7 391 Gene3D G3DSA:3.10.580.10 2 126 1.8E-17 T 23-10-2018 A3L08_07530 dc28f25f759f7b8044189213631d4b9c 153 Pfam PF01850 PIN domain 6 140 4.4E-12 T 23-10-2018 IPR002716 PIN domain A3L08_07530 dc28f25f759f7b8044189213631d4b9c 153 Gene3D G3DSA:3.40.50.1010 6 143 1.6E-10 T 23-10-2018 A3L08_07530 dc28f25f759f7b8044189213631d4b9c 153 SUPERFAMILY SSF88723 6 145 1.23E-16 T 23-10-2018 IPR029060 PIN-like domain superfamily A3L08_07195 09f637fbd8eb85bdb8cedfde2dea12b5 364 Pfam PF02915 Rubrerythrin 13 137 4.3E-6 T 23-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 A3L08_07195 09f637fbd8eb85bdb8cedfde2dea12b5 364 SUPERFAMILY SSF47240 11 139 1.31E-12 T 23-10-2018 IPR009078 Ferritin-like superfamily A3L08_07195 09f637fbd8eb85bdb8cedfde2dea12b5 364 Pfam PF01988 VIT family 148 353 5.0E-44 T 23-10-2018 IPR008217 Ccc1 family A3L08_07195 09f637fbd8eb85bdb8cedfde2dea12b5 364 Gene3D G3DSA:1.20.1260.10 13 143 2.2E-5 T 23-10-2018 IPR012347 Ferritin-like A3L08_00075 9959ad5f9eee6cdbc7ecf35063b48a4f 193 Gene3D G3DSA:3.40.50.300 2 143 9.2E-45 T 23-10-2018 A3L08_00075 9959ad5f9eee6cdbc7ecf35063b48a4f 193 SUPERFAMILY SSF52540 6 144 3.31E-38 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_00075 9959ad5f9eee6cdbc7ecf35063b48a4f 193 Pfam PF00265 Thymidine kinase 7 190 3.2E-51 T 23-10-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 A3L08_00075 9959ad5f9eee6cdbc7ecf35063b48a4f 193 PIRSF PIRSF035805 4 193 1.4E-64 T 23-10-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 A3L08_00075 9959ad5f9eee6cdbc7ecf35063b48a4f 193 Gene3D G3DSA:3.30.60.20 145 193 9.9E-24 T 23-10-2018 A3L08_00075 9959ad5f9eee6cdbc7ecf35063b48a4f 193 SUPERFAMILY SSF57716 145 192 1.05E-15 T 23-10-2018 A3L08_00075 9959ad5f9eee6cdbc7ecf35063b48a4f 193 ProSitePatterns PS00603 Thymidine kinase cellular-type signature. 177 190 - T 23-10-2018 IPR020633 Thymidine kinase, conserved site GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 A3L08_00075 9959ad5f9eee6cdbc7ecf35063b48a4f 193 Hamap MF_00124 Thymidine kinase [tdk]. 5 193 35.324 T 23-10-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 A3L08_09365 f9ac1162631f7a54519f542d1ac414f8 245 Gene3D G3DSA:3.40.50.300 1 235 1.4E-76 T 23-10-2018 A3L08_09365 f9ac1162631f7a54519f542d1ac414f8 245 SUPERFAMILY SSF52540 1 235 3.34E-65 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_09365 f9ac1162631f7a54519f542d1ac414f8 245 TIGRFAM TIGR01969 minD_arch: cell division ATPase MinD 3 236 9.7E-102 T 23-10-2018 IPR010224 ATP binding protein MinD, archaea A3L08_09365 f9ac1162631f7a54519f542d1ac414f8 245 Pfam PF13614 AAA domain 3 147 1.1E-27 T 23-10-2018 IPR025669 AAA domain A3L08_09365 f9ac1162631f7a54519f542d1ac414f8 245 PIRSF PIRSF003092 1 241 7.1E-58 T 23-10-2018 IPR025501 ATP binding protein MinD A3L08_02735 6c51ba60fd1c7cc786fd410b153e0a04 249 Gene3D G3DSA:3.40.50.300 2 249 1.2E-72 T 23-10-2018 A3L08_02735 6c51ba60fd1c7cc786fd410b153e0a04 249 Pfam PF06745 KaiC 10 246 2.4E-77 T 23-10-2018 IPR014774 KaiC-like domain A3L08_02735 6c51ba60fd1c7cc786fd410b153e0a04 249 SUPERFAMILY SSF52540 7 244 1.23E-43 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_03345 2d845d1c71e6bff94770a9eafe1835ea 736 SUPERFAMILY SSF48239 57 256 3.0E-18 T 23-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid A3L08_03345 2d845d1c71e6bff94770a9eafe1835ea 736 Gene3D G3DSA:1.50.10.20 21 180 5.7E-16 T 23-10-2018 A3L08_03345 2d845d1c71e6bff94770a9eafe1835ea 736 Gene3D G3DSA:1.50.10.20 277 485 6.6E-14 T 23-10-2018 A3L08_03345 2d845d1c71e6bff94770a9eafe1835ea 736 SUPERFAMILY SSF48239 257 489 2.2E-16 T 23-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid A3L08_07460 3b484846e0ebdeab5a71c0c2dc32e25c 330 PIRSF PIRSF005644 2 330 4.0E-96 T 23-10-2018 IPR011854 Carbamoyl dehydratase HypE A3L08_07460 3b484846e0ebdeab5a71c0c2dc32e25c 330 Pfam PF00586 AIR synthase related protein, N-terminal domain 37 140 2.3E-18 T 23-10-2018 IPR016188 PurM-like, N-terminal domain A3L08_07460 3b484846e0ebdeab5a71c0c2dc32e25c 330 SUPERFAMILY SSF56042 146 322 7.33E-38 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A3L08_07460 3b484846e0ebdeab5a71c0c2dc32e25c 330 Pfam PF02769 AIR synthase related protein, C-terminal domain 152 308 1.1E-26 T 23-10-2018 IPR010918 PurM-like, C-terminal domain A3L08_07460 3b484846e0ebdeab5a71c0c2dc32e25c 330 Gene3D G3DSA:3.90.650.10 146 330 9.1E-53 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A3L08_07460 3b484846e0ebdeab5a71c0c2dc32e25c 330 SUPERFAMILY SSF55326 5 144 2.44E-28 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A3L08_07460 3b484846e0ebdeab5a71c0c2dc32e25c 330 Gene3D G3DSA:3.30.1330.10 10 144 1.5E-31 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A3L08_04465 ae6c845a85bcdb818b8c0ef0b5e44c29 228 Hamap MF_00756 Ribonuclease P protein component 3 [rnp3]. 18 228 23.507 T 23-10-2018 IPR023539 Ribonuclease P, protein component 3, archaeal GO:0001682|GO:0004526 A3L08_04465 ae6c845a85bcdb818b8c0ef0b5e44c29 228 Pfam PF01876 RNase P subunit p30 28 217 1.3E-33 T 23-10-2018 IPR002738 RNase P subunit p30 GO:0004540|GO:0008033 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 A3L08_04465 ae6c845a85bcdb818b8c0ef0b5e44c29 228 Gene3D G3DSA:3.20.20.140 8 227 4.7E-100 T 23-10-2018 A3L08_04465 ae6c845a85bcdb818b8c0ef0b5e44c29 228 SUPERFAMILY SSF89550 20 224 2.71E-33 T 23-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 A3L08_04465 ae6c845a85bcdb818b8c0ef0b5e44c29 228 ProDom PD016938 P COMPONENT RIBONUCLEASE RNASE HYDROLASE PROCESSING TRNA SUBUNIT SIMILAR P/RNASE 124 216 1.0E-34 T 23-10-2018 A3L08_00030 5e008ab338b3ba7633d4f78408af7de3 142 Gene3D G3DSA:3.40.50.720 4 142 2.3E-50 T 23-10-2018 A3L08_00030 5e008ab338b3ba7633d4f78408af7de3 142 SUPERFAMILY SSF51735 7 139 3.69E-46 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L08_00030 5e008ab338b3ba7633d4f78408af7de3 142 SMART SM00881 18 111 6.9E-32 T 23-10-2018 IPR003781 CoA-binding GO:0048037 A3L08_00030 5e008ab338b3ba7633d4f78408af7de3 142 Pfam PF13380 CoA binding domain 23 137 4.4E-41 T 23-10-2018 IPR003781 CoA-binding GO:0048037 A3L08_06920 e3695e551b4bac1cf42dfc9f6feb0270 387 Pfam PF00474 Sodium:solute symporter family 5 334 5.8E-42 T 23-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 A3L08_06920 e3695e551b4bac1cf42dfc9f6feb0270 387 Gene3D G3DSA:1.20.1730.10 1 385 3.2E-75 T 23-10-2018 IPR038377 Sodium/glucose symporter superfamily A3L08_06920 e3695e551b4bac1cf42dfc9f6feb0270 387 ProSitePatterns PS00457 Sodium:solute symporter family signature 2. 316 336 - T 23-10-2018 IPR018212 Sodium/solute symporter, conserved site A3L08_04590 474be882ca5f203b215469b001e7e27e 687 Pfam PF05753 Translocon-associated protein beta (TRAPB) 336 450 3.4E-7 T 23-10-2018 A3L08_00225 20c027b45ab3b01c9a977552e118a542 96 Pfam PF09946 Predicted membrane protein (DUF2178) 5 61 1.8E-5 T 23-10-2018 IPR019235 Protein of unknown function DUF2178, transmembrane A3L08_09645 3af24a1dbfd629efd9da9dec24e7852d 580 SUPERFAMILY SSF90123 11 321 4.45E-81 T 23-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A3L08_09645 3af24a1dbfd629efd9da9dec24e7852d 580 SUPERFAMILY SSF52540 329 573 2.31E-86 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_09645 3af24a1dbfd629efd9da9dec24e7852d 580 Gene3D G3DSA:3.40.50.300 334 578 3.6E-90 T 23-10-2018 A3L08_09645 3af24a1dbfd629efd9da9dec24e7852d 580 SMART SM00382 363 549 3.0E-17 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L08_09645 3af24a1dbfd629efd9da9dec24e7852d 580 Gene3D G3DSA:1.20.1560.10 2 325 7.5E-93 T 23-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 A3L08_09645 3af24a1dbfd629efd9da9dec24e7852d 580 ProSitePatterns PS00211 ABC transporters family signature. 475 489 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L08_09645 3af24a1dbfd629efd9da9dec24e7852d 580 Pfam PF00664 ABC transporter transmembrane region 24 293 1.9E-57 T 23-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 A3L08_09645 3af24a1dbfd629efd9da9dec24e7852d 580 Pfam PF00005 ABC transporter 354 502 2.4E-33 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L08_04355 eb28df9c93c1a90f265c9b98ef8c98f2 445 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 326 424 5.3E-17 T 23-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 A3L08_04355 eb28df9c93c1a90f265c9b98ef8c98f2 445 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 268 275 3.5E-22 T 23-10-2018 A3L08_04355 eb28df9c93c1a90f265c9b98ef8c98f2 445 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 3.5E-22 T 23-10-2018 A3L08_04355 eb28df9c93c1a90f265c9b98ef8c98f2 445 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 228 242 3.5E-22 T 23-10-2018 A3L08_04355 eb28df9c93c1a90f265c9b98ef8c98f2 445 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 144 169 3.5E-22 T 23-10-2018 A3L08_04355 eb28df9c93c1a90f265c9b98ef8c98f2 445 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 297 1.2E-58 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A3L08_04355 eb28df9c93c1a90f265c9b98ef8c98f2 445 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 227 243 7.7E-28 T 23-10-2018 A3L08_04355 eb28df9c93c1a90f265c9b98ef8c98f2 445 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 144 162 7.7E-28 T 23-10-2018 A3L08_04355 eb28df9c93c1a90f265c9b98ef8c98f2 445 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 98 116 7.7E-28 T 23-10-2018 A3L08_04355 eb28df9c93c1a90f265c9b98ef8c98f2 445 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 253 275 7.7E-28 T 23-10-2018 A3L08_04355 eb28df9c93c1a90f265c9b98ef8c98f2 445 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 7.7E-28 T 23-10-2018 A3L08_04355 eb28df9c93c1a90f265c9b98ef8c98f2 445 Gene3D G3DSA:3.50.50.60 107 423 4.2E-119 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L08_04355 eb28df9c93c1a90f265c9b98ef8c98f2 445 SUPERFAMILY SSF51905 2 306 4.92E-48 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L08_04355 eb28df9c93c1a90f265c9b98ef8c98f2 445 SUPERFAMILY SSF55424 318 441 2.58E-26 T 23-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 A3L08_04355 eb28df9c93c1a90f265c9b98ef8c98f2 445 Gene3D G3DSA:3.50.50.60 5 333 4.2E-119 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L08_01980 4327601ee629043799e054ec9c81b5bb 177 SMART SM00903 5 156 8.8E-20 T 23-10-2018 IPR002563 Flavin reductase like domain GO:0010181 A3L08_01980 4327601ee629043799e054ec9c81b5bb 177 SUPERFAMILY SSF50475 3 156 5.89E-38 T 23-10-2018 A3L08_01980 4327601ee629043799e054ec9c81b5bb 177 Gene3D G3DSA:2.30.110.10 1 163 3.8E-44 T 23-10-2018 IPR012349 FMN-binding split barrel GO:0048037 A3L08_01980 4327601ee629043799e054ec9c81b5bb 177 Pfam PF01613 Flavin reductase like domain 8 140 1.9E-22 T 23-10-2018 IPR002563 Flavin reductase like domain GO:0010181 A3L08_07630 4167b205351de5662cf121db414a27a6 176 SUPERFAMILY SSF55729 3 173 1.43E-39 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase A3L08_07630 4167b205351de5662cf121db414a27a6 176 Gene3D G3DSA:3.40.630.30 6 173 2.3E-41 T 23-10-2018 A3L08_07630 4167b205351de5662cf121db414a27a6 176 Pfam PF13302 Acetyltransferase (GNAT) domain 19 149 4.5E-25 T 23-10-2018 IPR000182 GNAT domain A3L08_00825 b9ad535b654c86518c5d1acebd9dda88 302 Pfam PF00953 Glycosyl transferase family 4 69 215 2.9E-32 T 23-10-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 A3L08_01610 4ab411db44f639a60e624b6133b1b5de 123 ProSitePatterns PS00028 Zinc finger C2H2 type domain signature. 58 79 - T 23-10-2018 IPR013087 Zinc finger C2H2-type GO:0003676 A3L08_02595 b6b0b2e3bd219684d015de8cf0d784b4 102 Pfam PF01990 ATP synthase (F/14-kDa) subunit 3 90 2.5E-16 T 23-10-2018 IPR008218 ATPase, V1 complex, subunit F GO:0034220 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A3L08_02595 b6b0b2e3bd219684d015de8cf0d784b4 102 SUPERFAMILY SSF159468 3 100 9.02E-19 T 23-10-2018 IPR036906 ATPase, V1 complex, subunit F superfamily GO:0034220 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A3L08_02595 b6b0b2e3bd219684d015de8cf0d784b4 102 Hamap MF_00312 V-type ATP synthase subunit F [atpF]. 1 101 18.64 T 23-10-2018 IPR022944 ATPase, V1 complex, subunit F, bacterial/archaeal A3L08_02595 b6b0b2e3bd219684d015de8cf0d784b4 102 Gene3D G3DSA:3.40.50.10580 1 102 2.1E-31 T 23-10-2018 IPR036906 ATPase, V1 complex, subunit F superfamily GO:0034220 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A3L08_08230 c78ebbbcfa06f75ff2d58e94e2b1616f 119 SUPERFAMILY SSF52833 27 111 3.52E-16 T 23-10-2018 IPR036249 Thioredoxin-like superfamily A3L08_08230 c78ebbbcfa06f75ff2d58e94e2b1616f 119 Pfam PF13192 Thioredoxin domain 33 107 1.6E-9 T 23-10-2018 IPR012336 Thioredoxin-like fold A3L08_08230 c78ebbbcfa06f75ff2d58e94e2b1616f 119 Gene3D G3DSA:3.40.30.10 16 109 1.4E-15 T 23-10-2018 A3L08_02100 4432fa1a210520e6d9c8c6ca661dbadf 185 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 45 60 4.6E-5 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L08_02100 4432fa1a210520e6d9c8c6ca661dbadf 185 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 13 28 4.6E-5 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L08_02100 4432fa1a210520e6d9c8c6ca661dbadf 185 SMART SM00418 11 87 1.2E-9 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L08_02100 4432fa1a210520e6d9c8c6ca661dbadf 185 Gene3D G3DSA:1.10.10.10 1 85 1.8E-21 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L08_02100 4432fa1a210520e6d9c8c6ca661dbadf 185 SUPERFAMILY SSF46785 3 133 1.66E-23 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L08_02100 4432fa1a210520e6d9c8c6ca661dbadf 185 Pfam PF12840 Helix-turn-helix domain 14 64 1.2E-12 T 23-10-2018 A3L08_09215 b9cc2ceb53b1fb4949fd692cc40ec7d7 396 SMART SM00490 219 300 1.0E-33 T 23-10-2018 IPR001650 Helicase, C-terminal A3L08_09215 b9cc2ceb53b1fb4949fd692cc40ec7d7 396 Pfam PF00270 DEAD/DEAH box helicase 3 157 3.6E-44 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A3L08_09215 b9cc2ceb53b1fb4949fd692cc40ec7d7 396 SMART SM00487 1 183 6.3E-49 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A3L08_09215 b9cc2ceb53b1fb4949fd692cc40ec7d7 396 Gene3D G3DSA:3.40.50.300 178 366 2.5E-53 T 23-10-2018 A3L08_09215 b9cc2ceb53b1fb4949fd692cc40ec7d7 396 Pfam PF00271 Helicase conserved C-terminal domain 195 300 9.3E-27 T 23-10-2018 IPR001650 Helicase, C-terminal A3L08_09215 b9cc2ceb53b1fb4949fd692cc40ec7d7 396 SUPERFAMILY SSF52540 34 322 4.73E-77 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_09215 b9cc2ceb53b1fb4949fd692cc40ec7d7 396 Gene3D G3DSA:3.40.50.300 1 172 2.0E-64 T 23-10-2018 A3L08_09215 b9cc2ceb53b1fb4949fd692cc40ec7d7 396 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 114 122 - T 23-10-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site A3L08_06795 95b72fd92ecaf9e92b500a99e60affff 72 Pfam PF02381 MraZ protein, putative antitoxin-like 8 46 9.7E-6 T 23-10-2018 IPR020603 MraZ domain A3L08_06795 95b72fd92ecaf9e92b500a99e60affff 72 SUPERFAMILY SSF89447 1 52 3.92E-7 T 23-10-2018 IPR037914 SpoVT-AbrB domain superfamily A3L08_06795 95b72fd92ecaf9e92b500a99e60affff 72 Gene3D G3DSA:2.40.330.20 2 69 1.1E-6 T 23-10-2018 IPR038619 MraZ superfamily A3L08_06795 95b72fd92ecaf9e92b500a99e60affff 72 ProDom PD006745 MRAZ YABB DIVISION CELL 3D-STRUCTURE UNCHARACTERIZED BCR SIMILAR PROTEIN 9 46 8.0E-4 T 23-10-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 A3L08_06795 95b72fd92ecaf9e92b500a99e60affff 72 SMART SM00966 6 46 0.0032 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 A3L08_06210 214596e09b020e6b71da3f3b7f366740 235 Pfam PF04039 Domain related to MnhB subunit of Na+/H+ antiporter 98 221 1.1E-23 T 23-10-2018 IPR007182 Na+/H+ antiporter MnhB subunit-related protein A3L08_01250 74d8b85c3620ee28f0342d57d0d0811b 215 Gene3D G3DSA:1.20.58.220 3 212 1.2E-48 T 23-10-2018 IPR038078 PhoU-like domain superfamily A3L08_01250 74d8b85c3620ee28f0342d57d0d0811b 215 Pfam PF01865 Protein of unknown function DUF47 7 211 5.5E-42 T 23-10-2018 IPR018445 Putative phosphate transport regulator A3L08_01250 74d8b85c3620ee28f0342d57d0d0811b 215 SUPERFAMILY SSF109755 25 209 3.14E-8 T 23-10-2018 A3L08_01250 74d8b85c3620ee28f0342d57d0d0811b 215 TIGRFAM TIGR00153 TIGR00153: TIGR00153 family protein 16 214 2.9E-39 T 23-10-2018 IPR002727 Protein of unknown function DUF47 A3L08_08970 d168a3ae8a3e6f05eda6103fb4e7a5d3 351 TIGRFAM TIGR04288 CGP_CTERM: CGP-CTERM domain 330 349 1.2E-7 T 23-10-2018 IPR027552 CGP-CTERM domain A3L08_08970 d168a3ae8a3e6f05eda6103fb4e7a5d3 351 SUPERFAMILY SSF52317 83 311 7.32E-5 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A3L08_04390 eb35d69bcebf6d260f0afe287f2c9344 263 Gene3D G3DSA:3.40.1160.10 1 262 6.2E-61 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily A3L08_04390 eb35d69bcebf6d260f0afe287f2c9344 263 PIRSF PIRSF016496 1 263 1.5E-82 T 23-10-2018 IPR024192 Fosfomycin resistance kinase, FomA-type GO:0016301 KEGG: 00900+2.7.4.26|MetaCyc: PWY-6174|MetaCyc: PWY-7524 A3L08_04390 eb35d69bcebf6d260f0afe287f2c9344 263 Pfam PF00696 Amino acid kinase family 1 236 4.7E-42 T 23-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 A3L08_04390 eb35d69bcebf6d260f0afe287f2c9344 263 SUPERFAMILY SSF53633 1 262 3.67E-33 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily A3L08_00480 bfff8af9a538a99de46b9beaa0ca17ba 399 Pfam PF07728 AAA domain (dynein-related subfamily) 34 184 8.7E-7 T 23-10-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 A3L08_00480 bfff8af9a538a99de46b9beaa0ca17ba 399 SUPERFAMILY SSF52540 28 276 2.41E-19 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_00480 bfff8af9a538a99de46b9beaa0ca17ba 399 Gene3D G3DSA:3.40.50.300 18 209 1.9E-22 T 23-10-2018 A3L08_00480 bfff8af9a538a99de46b9beaa0ca17ba 399 SMART SM00382 30 208 0.0014 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L08_01770 f631ea81b01ecfbc59fb7a4f71cacc9a 511 Pfam PF00361 Proton-conducting membrane transporter 134 434 1.3E-63 T 23-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L08_01770 f631ea81b01ecfbc59fb7a4f71cacc9a 511 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 317 329 5.9E-15 T 23-10-2018 A3L08_01770 f631ea81b01ecfbc59fb7a4f71cacc9a 511 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 110 130 5.9E-15 T 23-10-2018 A3L08_01770 f631ea81b01ecfbc59fb7a4f71cacc9a 511 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 222 243 5.9E-15 T 23-10-2018 A3L08_01770 f631ea81b01ecfbc59fb7a4f71cacc9a 511 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 82 107 5.9E-15 T 23-10-2018 A3L08_01770 f631ea81b01ecfbc59fb7a4f71cacc9a 511 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 72 120 1.5E-12 T 23-10-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L08_04995 14431fc975f6f4891b7dc76caed8bbd7 225 Gene3D G3DSA:1.10.150.240 13 85 3.8E-12 T 23-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 A3L08_04995 14431fc975f6f4891b7dc76caed8bbd7 225 SUPERFAMILY SSF56784 1 185 3.5E-18 T 23-10-2018 IPR036412 HAD-like superfamily A3L08_04995 14431fc975f6f4891b7dc76caed8bbd7 225 Gene3D G3DSA:3.40.50.1000 5 135 3.8E-12 T 23-10-2018 IPR023214 HAD superfamily A3L08_04995 14431fc975f6f4891b7dc76caed8bbd7 225 Pfam PF13419 Haloacid dehalogenase-like hydrolase 3 135 1.4E-12 T 23-10-2018 A3L08_07035 6a2018186e90dad95eec7e1461ed42ac 305 Pfam PF01384 Phosphate transporter family 14 297 1.3E-51 T 23-10-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 A3L08_04745 469822e84aa175abf1b38d1c0cc13e9d 67 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 14 25 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L08_04745 469822e84aa175abf1b38d1c0cc13e9d 67 SUPERFAMILY SSF54862 3 64 2.05E-17 T 23-10-2018 A3L08_04745 469822e84aa175abf1b38d1c0cc13e9d 67 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 43 54 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L08_04745 469822e84aa175abf1b38d1c0cc13e9d 67 Gene3D G3DSA:3.30.70.20 1 31 2.2E-6 T 23-10-2018 A3L08_04745 469822e84aa175abf1b38d1c0cc13e9d 67 Pfam PF00037 4Fe-4S binding domain 40 58 2.0E-8 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L08_04745 469822e84aa175abf1b38d1c0cc13e9d 67 Pfam PF00037 4Fe-4S binding domain 7 30 2.9E-6 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L08_04745 469822e84aa175abf1b38d1c0cc13e9d 67 Gene3D G3DSA:3.30.70.20 32 67 4.6E-7 T 23-10-2018 A3L08_08825 0d41d0cbbf24edd12ada15a6d7b7e668 321 SUPERFAMILY SSF46785 263 316 5.74E-12 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L08_08825 0d41d0cbbf24edd12ada15a6d7b7e668 321 Pfam PF12802 MarR family 265 307 2.4E-8 T 23-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A3L08_08825 0d41d0cbbf24edd12ada15a6d7b7e668 321 Gene3D G3DSA:1.10.10.10 240 319 5.5E-11 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L08_04245 ab56fdf6151a2739bb436faa514baf57 142 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 1 132 20.611 T 23-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 A3L08_04245 ab56fdf6151a2739bb436faa514baf57 142 TIGRFAM TIGR01077 L13_A_E: ribosomal protein uL13 3 142 3.3E-64 T 23-10-2018 IPR005755 Ribosomal protein L13, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 A3L08_04245 ab56fdf6151a2739bb436faa514baf57 142 SUPERFAMILY SSF52161 2 142 9.03E-44 T 23-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 A3L08_04245 ab56fdf6151a2739bb436faa514baf57 142 Gene3D G3DSA:3.90.1180.10 1 142 1.1E-57 T 23-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 A3L08_04245 ab56fdf6151a2739bb436faa514baf57 142 PIRSF PIRSF002181 1 142 1.7E-43 T 23-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 A3L08_04245 ab56fdf6151a2739bb436faa514baf57 142 Pfam PF00572 Ribosomal protein L13 3 103 6.8E-12 T 23-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 A3L08_04245 ab56fdf6151a2739bb436faa514baf57 142 ProSitePatterns PS00783 Ribosomal protein L13 signature. 79 102 - T 23-10-2018 IPR023563 Ribosomal protein L13, conserved site GO:0003735|GO:0005840|GO:0006412 A3L08_04925 7248ca6e990e81da02652ec5cefa51fe 453 SUPERFAMILY SSF103473 8 440 4.84E-60 T 23-10-2018 IPR036259 MFS transporter superfamily A3L08_04925 7248ca6e990e81da02652ec5cefa51fe 453 Gene3D G3DSA:1.20.1250.20 4 270 2.9E-35 T 23-10-2018 A3L08_04925 7248ca6e990e81da02652ec5cefa51fe 453 Gene3D G3DSA:1.20.1250.20 271 445 5.6E-19 T 23-10-2018 A3L08_04925 7248ca6e990e81da02652ec5cefa51fe 453 Pfam PF07690 Major Facilitator Superfamily 12 261 8.7E-33 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A3L08_04925 7248ca6e990e81da02652ec5cefa51fe 453 Pfam PF07690 Major Facilitator Superfamily 283 430 5.7E-19 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A3L08_04635 815d27915dd9ad756ce5d09aaa2e9fd6 107 SMART SM00661 26 72 0.0088 T 23-10-2018 IPR001529 DNA-directed RNA polymerase, M/15kDa subunit GO:0006351 A3L08_04635 815d27915dd9ad756ce5d09aaa2e9fd6 107 Pfam PF06677 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) 16 48 9.0E-14 T 23-10-2018 IPR009563 Sjoegren syndrome/scleroderma autoantigen 1 A3L08_05250 a1b7048096831b4de36b4205ee0a7a1c 364 TIGRFAM TIGR00832 acr3: arsenical-resistance protein 6 341 3.4E-117 T 23-10-2018 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 A3L08_05250 a1b7048096831b4de36b4205ee0a7a1c 364 Pfam PF01758 Sodium Bile acid symporter family 52 253 1.0E-46 T 23-10-2018 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 A3L08_05250 a1b7048096831b4de36b4205ee0a7a1c 364 PIRSF PIRSF005508 1 358 5.3E-140 T 23-10-2018 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 A3L08_05250 a1b7048096831b4de36b4205ee0a7a1c 364 Gene3D G3DSA:1.20.1530.20 3 343 1.2E-22 T 23-10-2018 IPR038770 Sodium/solute symporter superfamily A3L08_06745 8ba03cb7772768b0ade99ef3b9f2d34e 115 SUPERFAMILY SSF55620 1 114 3.22E-33 T 23-10-2018 A3L08_06745 8ba03cb7772768b0ade99ef3b9f2d34e 115 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 6 113 1.5E-28 T 23-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 A3L08_06745 8ba03cb7772768b0ade99ef3b9f2d34e 115 Gene3D G3DSA:3.30.479.10 1 115 1.5E-39 T 23-10-2018 IPR038418 6-pyruvoyl tetrahydropterin synthase/QueD superfamily Reactome: R-HSA-1474151 A3L08_06745 8ba03cb7772768b0ade99ef3b9f2d34e 115 PIRSF PIRSF006113 1 115 2.8E-33 T 23-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 A3L08_00055 b20237a94527db942f31acdd0c557271 222 TIGRFAM TIGR00703 TIGR00703: TIGR00703 family protein 1 222 2.4E-98 T 23-10-2018 IPR005266 Uncharacterised protein family UPF0128 A3L08_00055 b20237a94527db942f31acdd0c557271 222 Pfam PF03673 Uncharacterised protein family (UPF0128) 1 222 2.3E-106 T 23-10-2018 IPR005266 Uncharacterised protein family UPF0128 A3L08_00055 b20237a94527db942f31acdd0c557271 222 Hamap MF_00264 UPF0128 protein . 1 222 135.424 T 23-10-2018 IPR005266 Uncharacterised protein family UPF0128 A3L08_00055 b20237a94527db942f31acdd0c557271 222 ProDom PD023377 UPF0128 PYRAB08320 PH1314 PF1488 MJ1463 AQ_756 1 222 3.0E-121 T 23-10-2018 IPR005266 Uncharacterised protein family UPF0128 A3L08_01060 e5e115ba08b60408274a8c1cd0979087 138 SUPERFAMILY SSF103481 38 137 6.41E-10 T 23-10-2018 A3L08_01060 e5e115ba08b60408274a8c1cd0979087 138 Pfam PF00892 EamA-like transporter family 5 137 1.7E-24 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A3L08_01010 636c6a2759baa073cb9712c8e1e2a15b 200 Hamap MF_02113_A Proteasome subunit beta [prcB]. 3 199 34.607 T 23-10-2018 IPR019983 Peptidase T1A, proteasome beta-subunit, archaeal GO:0004175|GO:0005839|GO:0051603 A3L08_01010 636c6a2759baa073cb9712c8e1e2a15b 200 PRINTS PR00141 Proteasome component signature 135 146 4.8E-5 T 23-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 A3L08_01010 636c6a2759baa073cb9712c8e1e2a15b 200 PRINTS PR00141 Proteasome component signature 15 30 4.8E-5 T 23-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 A3L08_01010 636c6a2759baa073cb9712c8e1e2a15b 200 PRINTS PR00141 Proteasome component signature 146 157 4.8E-5 T 23-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 A3L08_01010 636c6a2759baa073cb9712c8e1e2a15b 200 Gene3D G3DSA:3.60.20.10 1 198 2.5E-62 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A3L08_01010 636c6a2759baa073cb9712c8e1e2a15b 200 SUPERFAMILY SSF56235 2 193 3.87E-59 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A3L08_01010 636c6a2759baa073cb9712c8e1e2a15b 200 ProSitePatterns PS00854 Proteasome beta-type subunits signature. 11 58 - T 23-10-2018 IPR016050 Proteasome beta-type subunit, conserved site GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 A3L08_01010 636c6a2759baa073cb9712c8e1e2a15b 200 Pfam PF00227 Proteasome subunit 5 186 1.2E-52 T 23-10-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 A3L08_01010 636c6a2759baa073cb9712c8e1e2a15b 200 TIGRFAM TIGR03634 arc_protsome_B: proteasome endopeptidase complex, archaeal, beta subunit 7 191 8.2E-78 T 23-10-2018 IPR019983 Peptidase T1A, proteasome beta-subunit, archaeal GO:0004175|GO:0005839|GO:0051603 A3L08_04015 9a81dac64dea1b271b203d5bf77b5b6f 193 Gene3D G3DSA:3.40.50.300 3 171 9.8E-16 T 23-10-2018 A3L08_04015 9a81dac64dea1b271b203d5bf77b5b6f 193 SUPERFAMILY SSF52540 19 169 4.07E-11 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_04015 9a81dac64dea1b271b203d5bf77b5b6f 193 Pfam PF00437 Type II/IV secretion system protein 7 110 2.9E-7 T 23-10-2018 IPR001482 Type II/IV secretion system protein A3L08_03595 084845e6f8c2aaffbf3b6f27da8ee703 154 SUPERFAMILY SSF54909 85 153 9.65E-9 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel A3L08_03595 084845e6f8c2aaffbf3b6f27da8ee703 154 Gene3D G3DSA:3.30.70.920 84 150 1.6E-10 T 23-10-2018 A3L08_03595 084845e6f8c2aaffbf3b6f27da8ee703 154 SMART SM00419 21 72 8.5E-10 T 23-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 A3L08_03595 084845e6f8c2aaffbf3b6f27da8ee703 154 Pfam PF12802 MarR family 6 65 6.5E-9 T 23-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A3L08_03595 084845e6f8c2aaffbf3b6f27da8ee703 154 Gene3D G3DSA:1.10.10.10 10 82 1.2E-8 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L08_03595 084845e6f8c2aaffbf3b6f27da8ee703 154 SUPERFAMILY SSF46785 5 82 1.11E-11 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L08_03595 084845e6f8c2aaffbf3b6f27da8ee703 154 Pfam PF01037 Lrp/AsnC ligand binding domain 87 152 1.0E-8 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A3L08_03595 084845e6f8c2aaffbf3b6f27da8ee703 154 SMART SM00418 5 105 0.0046 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L08_00315 8d98840ba2663abb34f1fad6339025fc 212 Pfam PF03192 Pyrococcus protein of unknown function, DUF257 11 199 1.3E-13 T 23-10-2018 IPR005489 Protein of unknown function DUF257 A3L08_00315 8d98840ba2663abb34f1fad6339025fc 212 Gene3D G3DSA:3.40.50.11570 5 210 6.4E-17 T 23-10-2018 A3L08_00060 ff545faa87e70a295a0a8677e93c3998 141 Gene3D G3DSA:2.60.120.630 1 140 4.3E-53 T 23-10-2018 IPR023131 Mth639-like domain superfamily A3L08_00060 ff545faa87e70a295a0a8677e93c3998 141 Pfam PF04027 Domain of unknown function (DUF371) 6 137 2.1E-50 T 23-10-2018 IPR007171 Protein of unknown function DUF371 A3L08_01630 fccaa2762becb3e6290eeb58a48060e7 212 Hamap MF_00266 tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase [taw3]. 1 186 27.464 T 23-10-2018 IPR022908 tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase GO:0008175|GO:0030488|GO:0031591 MetaCyc: PWY-7286 A3L08_01630 fccaa2762becb3e6290eeb58a48060e7 212 Pfam PF02676 Methyltransferase TYW3 3 184 1.5E-41 T 23-10-2018 IPR003827 tRNA wybutosine-synthesizing protein MetaCyc: PWY-7286|Reactome: R-HSA-6782861 A3L08_01630 fccaa2762becb3e6290eeb58a48060e7 212 Gene3D G3DSA:3.30.1960.10 1 184 2.2E-50 T 23-10-2018 IPR036602 tRNA wybutosine-synthesizing-like superfamily MetaCyc: PWY-7286|Reactome: R-HSA-6782861 A3L08_01630 fccaa2762becb3e6290eeb58a48060e7 212 SUPERFAMILY SSF111278 2 183 9.68E-51 T 23-10-2018 IPR036602 tRNA wybutosine-synthesizing-like superfamily MetaCyc: PWY-7286|Reactome: R-HSA-6782861 A3L08_02015 7d20f791133e8e51de6df21d37f77bff 739 Pfam PF04042 DNA polymerase alpha/epsilon subunit B 473 676 4.1E-18 T 23-10-2018 IPR007185 DNA polymerase alpha/epsilon, subunit B GO:0003677|GO:0003887|GO:0006260 A3L08_02015 7d20f791133e8e51de6df21d37f77bff 739 Gene3D G3DSA:1.10.8.800 2 71 5.5E-24 T 23-10-2018 A3L08_02015 7d20f791133e8e51de6df21d37f77bff 739 SUPERFAMILY SSF56300 473 700 4.2E-19 T 23-10-2018 A3L08_02015 7d20f791133e8e51de6df21d37f77bff 739 Hamap MF_00325 DNA polymerase II small subunit [polB]. 2 729 32.675 T 23-10-2018 IPR011149 DNA polymerase II small subunit, archaeal GO:0003676|GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A3L08_02015 7d20f791133e8e51de6df21d37f77bff 739 Gene3D G3DSA:3.60.21.50 456 713 5.1E-26 T 23-10-2018 A3L08_02015 7d20f791133e8e51de6df21d37f77bff 739 PIRSF PIRSF000803 114 736 3.8E-176 T 23-10-2018 IPR011149 DNA polymerase II small subunit, archaeal GO:0003676|GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A3L08_04250 a11d664672ac69051cde913b928aff15 135 TIGRFAM TIGR03627 uS9_arch: ribosomal protein uS9 3 135 6.3E-62 T 23-10-2018 IPR019958 Ribosomal protein S9, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L08_04250 a11d664672ac69051cde913b928aff15 135 Hamap MF_00532_A 30S ribosomal protein S9 [rpsI]. 3 135 37.194 T 23-10-2018 IPR019958 Ribosomal protein S9, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L08_04250 a11d664672ac69051cde913b928aff15 135 Pfam PF00380 Ribosomal protein S9/S16 8 135 1.4E-30 T 23-10-2018 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 A3L08_04250 a11d664672ac69051cde913b928aff15 135 SUPERFAMILY SSF54211 3 135 5.31E-34 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A3L08_04250 a11d664672ac69051cde913b928aff15 135 ProSitePatterns PS00360 Ribosomal protein S9 signature. 68 86 - T 23-10-2018 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 A3L08_04250 a11d664672ac69051cde913b928aff15 135 Gene3D G3DSA:3.30.230.10 1 135 5.3E-51 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A3L08_00365 422df40cdf2995688cb346ab317bafc3 201 PIRSF PIRSF019239 29 201 1.6E-50 T 23-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 A3L08_00365 422df40cdf2995688cb346ab317bafc3 201 Pfam PF01899 Na+/H+ ion antiporter subunit 40 199 8.9E-42 T 23-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 A3L08_03280 9c1fd727f21570be726fbfb860071980 331 Gene3D G3DSA:3.30.470.20 87 330 1.8E-98 T 23-10-2018 A3L08_03280 9c1fd727f21570be726fbfb860071980 331 SUPERFAMILY SSF56059 101 331 2.02E-79 T 23-10-2018 A3L08_03280 9c1fd727f21570be726fbfb860071980 331 Gene3D G3DSA:3.30.1490.20 114 174 1.8E-98 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 A3L08_03280 9c1fd727f21570be726fbfb860071980 331 Pfam PF06973 Domain of unknown function (DUF1297) 150 331 1.0E-72 T 23-10-2018 IPR009720 IMP biosynthesis enzyme PurP, C-terminal GO:0000287|GO:0005524|GO:0006188|GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 A3L08_03280 9c1fd727f21570be726fbfb860071980 331 PIRSF PIRSF004602 1 331 2.1E-133 T 23-10-2018 IPR023656 IMP biosynthesis enzyme PurP GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 A3L08_03280 9c1fd727f21570be726fbfb860071980 331 SUPERFAMILY SSF52440 1 97 4.6E-31 T 23-10-2018 IPR016185 Pre-ATP-grasp domain superfamily A3L08_03280 9c1fd727f21570be726fbfb860071980 331 Gene3D G3DSA:3.40.50.20 1 85 1.1E-28 T 23-10-2018 A3L08_03280 9c1fd727f21570be726fbfb860071980 331 Pfam PF06849 Protein of unknown function (DUF1246) 3 117 2.6E-33 T 23-10-2018 IPR010672 IMP biosynthesis enzyme PurP, N-terminal GO:0000287|GO:0005524|GO:0006188|GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 A3L08_03280 9c1fd727f21570be726fbfb860071980 331 Hamap MF_01163 5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase [purP]. 1 331 49.67 T 23-10-2018 IPR023656 IMP biosynthesis enzyme PurP GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 A3L08_06195 7203d14dab9719c627736774265061d6 617 Pfam PF00361 Proton-conducting membrane transporter 116 423 1.2E-61 T 23-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L08_01810 e582fa79df39d84c411caacd7dfd42b7 160 Pfam PF02915 Rubrerythrin 16 152 2.9E-17 T 23-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 A3L08_01810 e582fa79df39d84c411caacd7dfd42b7 160 SUPERFAMILY SSF47240 12 155 9.7E-27 T 23-10-2018 IPR009078 Ferritin-like superfamily A3L08_01810 e582fa79df39d84c411caacd7dfd42b7 160 Gene3D G3DSA:1.20.1260.10 6 156 3.6E-32 T 23-10-2018 IPR012347 Ferritin-like A3L08_09040 b12407406c9e93cf71d7e7699777ceaa 319 Pfam PF03308 ArgK protein 18 282 3.0E-102 T 23-10-2018 A3L08_09040 b12407406c9e93cf71d7e7699777ceaa 319 Gene3D G3DSA:3.40.50.300 43 252 8.0E-88 T 23-10-2018 A3L08_09040 b12407406c9e93cf71d7e7699777ceaa 319 SUPERFAMILY SSF52540 2 311 1.93E-80 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_09040 b12407406c9e93cf71d7e7699777ceaa 319 Gene3D G3DSA:1.20.5.170 1 42 3.1E-5 T 23-10-2018 A3L08_09040 b12407406c9e93cf71d7e7699777ceaa 319 SMART SM00382 44 194 3.7E-4 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L08_09040 b12407406c9e93cf71d7e7699777ceaa 319 TIGRFAM TIGR00750 lao: LAO/AO transport system ATPase 12 312 9.3E-129 T 23-10-2018 IPR005129 SIMIBI class G3E GTPase, ArgK/MeaB GO:0003924|GO:0005525 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 A3L08_05290 d55299d1b3a539cf8dc99b17046a73c2 82 Gene3D G3DSA:3.10.20.30 1 82 6.1E-24 T 23-10-2018 IPR012675 Beta-grasp domain superfamily A3L08_05290 d55299d1b3a539cf8dc99b17046a73c2 82 SUPERFAMILY SSF54285 2 82 1.09E-20 T 23-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp A3L08_05290 d55299d1b3a539cf8dc99b17046a73c2 82 Pfam PF02597 ThiS family 3 82 3.6E-21 T 23-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 A3L08_05290 d55299d1b3a539cf8dc99b17046a73c2 82 TIGRFAM TIGR01687 moaD_arch: MoaD family protein 1 82 4.8E-22 T 23-10-2018 IPR010038 MoaD, archaeal-type A3L08_06945 f9d6992656f4a0ea480210b9649de13a 338 SMART SM00382 37 251 1.4E-12 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L08_06945 f9d6992656f4a0ea480210b9649de13a 338 ProSitePatterns PS00211 ABC transporters family signature. 165 179 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L08_06945 f9d6992656f4a0ea480210b9649de13a 338 Pfam PF00005 ABC transporter 29 193 7.3E-26 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L08_06945 f9d6992656f4a0ea480210b9649de13a 338 Gene3D G3DSA:3.40.50.300 5 337 1.6E-80 T 23-10-2018 A3L08_06945 f9d6992656f4a0ea480210b9649de13a 338 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 245 311 1.1E-20 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A3L08_06945 f9d6992656f4a0ea480210b9649de13a 338 SUPERFAMILY SSF52540 6 272 3.03E-50 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_06945 f9d6992656f4a0ea480210b9649de13a 338 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 243 330 4.1E-28 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A3L08_09160 581bd53f5b7f45a7dcfbeeca68328ca5 445 SUPERFAMILY SSF141322 371 440 4.18E-18 T 23-10-2018 A3L08_09160 581bd53f5b7f45a7dcfbeeca68328ca5 445 Pfam PF01957 NfeD-like C-terminal, partner-binding 294 439 1.8E-36 T 23-10-2018 IPR002810 NfeD-like, C-terminal domain A3L08_09160 581bd53f5b7f45a7dcfbeeca68328ca5 445 Gene3D G3DSA:3.90.226.10 21 243 1.3E-67 T 23-10-2018 A3L08_09160 581bd53f5b7f45a7dcfbeeca68328ca5 445 Gene3D G3DSA:2.40.50.140 375 445 6.6E-24 T 23-10-2018 A3L08_09160 581bd53f5b7f45a7dcfbeeca68328ca5 445 SUPERFAMILY SSF52096 8 190 7.47E-32 T 23-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A3L08_09160 581bd53f5b7f45a7dcfbeeca68328ca5 445 Pfam PF00574 Clp protease 52 190 3.4E-10 T 23-10-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA A3L08_07620 1891e3e884fc097748cd6bb95cfdbc3a 463 Pfam PF00686 Starch binding domain 103 192 8.9E-7 T 23-10-2018 IPR002044 Carbohydrate binding module family 20 GO:2001070 A3L08_07620 1891e3e884fc097748cd6bb95cfdbc3a 463 SUPERFAMILY SSF49452 99 200 8.97E-16 T 23-10-2018 IPR013784 Carbohydrate-binding-like fold GO:0030246 A3L08_07620 1891e3e884fc097748cd6bb95cfdbc3a 463 Pfam PF00756 Putative esterase 227 459 1.4E-34 T 23-10-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 A3L08_07620 1891e3e884fc097748cd6bb95cfdbc3a 463 Gene3D G3DSA:3.40.50.1820 211 462 2.2E-65 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold A3L08_07620 1891e3e884fc097748cd6bb95cfdbc3a 463 Gene3D G3DSA:2.60.40.10 88 201 8.9E-12 T 23-10-2018 IPR013783 Immunoglobulin-like fold A3L08_07620 1891e3e884fc097748cd6bb95cfdbc3a 463 SMART SM01065 102 197 1.1E-17 T 23-10-2018 IPR002044 Carbohydrate binding module family 20 GO:2001070 A3L08_07620 1891e3e884fc097748cd6bb95cfdbc3a 463 SUPERFAMILY SSF53474 213 462 1.8E-56 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold A3L08_03455 271daa646fefc61e7c4709d532ef1597 216 PIRSF PIRSF000887 5 215 1.1E-37 T 23-10-2018 IPR024173 Phosphoesterase, MJ0037 A3L08_03455 271daa646fefc61e7c4709d532ef1597 216 Gene3D G3DSA:3.60.21.10 11 112 2.1E-10 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like A3L08_03455 271daa646fefc61e7c4709d532ef1597 216 SUPERFAMILY SSF56300 20 172 1.74E-14 T 23-10-2018 A3L08_03455 271daa646fefc61e7c4709d532ef1597 216 Pfam PF00149 Calcineurin-like phosphoesterase 20 120 7.4E-9 T 23-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 A3L08_04735 ae7f2fb3f099a341f91e49e1512d716b 226 Pfam PF00085 Thioredoxin 12 92 5.8E-5 T 23-10-2018 IPR013766 Thioredoxin domain GO:0045454 A3L08_04735 ae7f2fb3f099a341f91e49e1512d716b 226 Pfam PF13192 Thioredoxin domain 137 222 7.2E-15 T 23-10-2018 IPR012336 Thioredoxin-like fold A3L08_04735 ae7f2fb3f099a341f91e49e1512d716b 226 SUPERFAMILY SSF52833 121 221 1.14E-20 T 23-10-2018 IPR036249 Thioredoxin-like superfamily A3L08_04735 ae7f2fb3f099a341f91e49e1512d716b 226 TIGRFAM TIGR02187 GlrX_arch: glutaredoxin-like domain protein 4 223 2.2E-88 T 23-10-2018 IPR011903 Glutaredoxin-like domain A3L08_04735 ae7f2fb3f099a341f91e49e1512d716b 226 Gene3D G3DSA:3.40.30.10 120 225 9.3E-27 T 23-10-2018 A3L08_04735 ae7f2fb3f099a341f91e49e1512d716b 226 Gene3D G3DSA:3.40.30.10 1 117 3.5E-36 T 23-10-2018 A3L08_04735 ae7f2fb3f099a341f91e49e1512d716b 226 SUPERFAMILY SSF52833 5 116 1.41E-25 T 23-10-2018 IPR036249 Thioredoxin-like superfamily A3L08_01350 090769eb5f0bf45a855dbcdf9b9761a0 242 Pfam PF09883 Uncharacterized protein conserved in archaea (DUF2110) 6 235 5.9E-72 T 23-10-2018 IPR016757 Uncharacterised conserved protein UCP019322 A3L08_01350 090769eb5f0bf45a855dbcdf9b9761a0 242 PIRSF PIRSF019322 2 242 6.9E-89 T 23-10-2018 IPR016757 Uncharacterised conserved protein UCP019322 A3L08_08325 52291e9b57d86e0b5392efb073e2b4b9 65 Gene3D G3DSA:3.30.429.10 2 58 5.5E-18 T 23-10-2018 IPR014347 Tautomerase/MIF superfamily A3L08_08325 52291e9b57d86e0b5392efb073e2b4b9 65 SUPERFAMILY SSF55331 8 57 3.66E-9 T 23-10-2018 IPR014347 Tautomerase/MIF superfamily A3L08_08325 52291e9b57d86e0b5392efb073e2b4b9 65 Pfam PF01361 Tautomerase enzyme 5 57 1.4E-9 T 23-10-2018 IPR004370 4-oxalocrotonate tautomerase GO:0006725|GO:0016853 A3L08_06760 b7734d1568506e9ff2c6ef9870d4f99f 281 SUPERFAMILY SSF52518 19 253 1.59E-74 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold A3L08_06760 b7734d1568506e9ff2c6ef9870d4f99f 281 Gene3D G3DSA:3.40.50.970 86 250 1.2E-28 T 23-10-2018 A3L08_06760 b7734d1568506e9ff2c6ef9870d4f99f 281 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 56 202 7.8E-35 T 23-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 A3L08_01825 30c2666f6b41b7a9743394ca9a945d39 401 Gene3D G3DSA:3.40.50.300 47 235 7.6E-11 T 23-10-2018 A3L08_01825 30c2666f6b41b7a9743394ca9a945d39 401 SUPERFAMILY SSF52540 55 303 3.37E-23 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_01825 30c2666f6b41b7a9743394ca9a945d39 401 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 66 200 2.6E-4 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A3L08_09115 5bc43e61572e4bbe2d90b5f6cd758f40 231 Gene3D G3DSA:3.30.1360.40 4 85 8.2E-27 T 23-10-2018 A3L08_09115 5bc43e61572e4bbe2d90b5f6cd758f40 231 SUPERFAMILY SSF160467 5 93 1.83E-22 T 23-10-2018 A3L08_09115 5bc43e61572e4bbe2d90b5f6cd758f40 231 SUPERFAMILY SSF50891 88 218 1.25E-51 T 23-10-2018 IPR029000 Cyclophilin-like domain superfamily A3L08_09115 5bc43e61572e4bbe2d90b5f6cd758f40 231 Pfam PF02682 Carboxyltransferase domain, subdomain C and D 5 202 1.9E-79 T 23-10-2018 IPR003833 Carboxyltransferase domain, subdomain C and D A3L08_09115 5bc43e61572e4bbe2d90b5f6cd758f40 231 SMART SM00796 3 202 2.0E-113 T 23-10-2018 IPR003833 Carboxyltransferase domain, subdomain C and D A3L08_09115 5bc43e61572e4bbe2d90b5f6cd758f40 231 TIGRFAM TIGR00370 TIGR00370: sensor histidine kinase inhibitor, KipI family 9 211 5.9E-73 T 23-10-2018 IPR010016 KipI family KEGG: 00480+3.5.2.9|MetaCyc: PWY-4041|MetaCyc: PWY-7942 A3L08_09115 5bc43e61572e4bbe2d90b5f6cd758f40 231 Gene3D G3DSA:2.40.100.10 87 227 4.4E-66 T 23-10-2018 IPR029000 Cyclophilin-like domain superfamily A3L08_02150 cd861ce031de7dc6784430af08c01aae 343 Gene3D G3DSA:1.10.3720.10 107 337 3.2E-12 T 23-10-2018 IPR035906 MetI-like superfamily A3L08_02150 cd861ce031de7dc6784430af08c01aae 343 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 128 342 2.1E-19 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A3L08_02150 cd861ce031de7dc6784430af08c01aae 343 SUPERFAMILY SSF161098 109 302 2.78E-8 T 23-10-2018 IPR035906 MetI-like superfamily A3L08_08355 63fe2e0ded329f09d18879b626e7e810 231 SMART SM00382 27 212 2.7E-6 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L08_08355 63fe2e0ded329f09d18879b626e7e810 231 SUPERFAMILY SSF52540 3 219 4.62E-46 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_08355 63fe2e0ded329f09d18879b626e7e810 231 Gene3D G3DSA:3.40.50.300 1 224 2.5E-45 T 23-10-2018 A3L08_08355 63fe2e0ded329f09d18879b626e7e810 231 Pfam PF00005 ABC transporter 19 157 7.7E-21 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L08_08355 63fe2e0ded329f09d18879b626e7e810 231 ProSitePatterns PS00211 ABC transporters family signature. 129 143 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L08_08880 513d61f676841a8e373e788633b504e3 810 Gene3D G3DSA:3.40.50.11040 24 251 5.8E-12 T 23-10-2018 A3L08_08880 513d61f676841a8e373e788633b504e3 810 Pfam PF08351 Domain of unknown function (DUF1726) 129 221 6.7E-31 T 23-10-2018 IPR013562 tRNA(Met) cytidine acetyltransferase TmcA, N-terminal Reactome: R-HSA-6790901 A3L08_08880 513d61f676841a8e373e788633b504e3 810 Pfam PF13718 GNAT acetyltransferase 2 499 615 1.7E-33 T 23-10-2018 IPR000182 GNAT domain A3L08_08880 513d61f676841a8e373e788633b504e3 810 Gene3D G3DSA:3.40.50.12320 281 448 6.9E-34 T 23-10-2018 A3L08_08880 513d61f676841a8e373e788633b504e3 810 Hamap MF_01886 tRNA(Met) cytidine acetyltransferase TmcA [tmcA]. 39 807 47.937 T 23-10-2018 IPR024914 tRNA(Met) cytidine acetyltransferase TmcA GO:0000049|GO:0002101|GO:0051391|GO:0051392 A3L08_08880 513d61f676841a8e373e788633b504e3 810 Gene3D G3DSA:3.40.630.30 456 662 4.0E-55 T 23-10-2018 A3L08_08880 513d61f676841a8e373e788633b504e3 810 Pfam PF05127 Helicase 285 458 3.3E-55 T 23-10-2018 IPR007807 Helicase domain Reactome: R-HSA-6790901 A3L08_08880 513d61f676841a8e373e788633b504e3 810 SUPERFAMILY SSF55729 491 644 2.47E-10 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase A3L08_08880 513d61f676841a8e373e788633b504e3 810 SUPERFAMILY SSF52540 227 397 6.33E-8 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_04800 3dd7369ddda60383d3436dcd94981b74 374 SUPERFAMILY SSF52490 37 235 1.3E-70 T 23-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 A3L08_04800 3dd7369ddda60383d3436dcd94981b74 374 Pfam PF12327 FtsZ family, C-terminal domain 251 343 3.3E-32 T 23-10-2018 IPR024757 Cell division protein FtsZ, C-terminal A3L08_04800 3dd7369ddda60383d3436dcd94981b74 374 Gene3D G3DSA:3.30.1330.20 254 364 6.5E-35 T 23-10-2018 IPR037103 Tubulin/FtsZ, C-terminal domain superfamily Reactome: R-HSA-380320 A3L08_04800 3dd7369ddda60383d3436dcd94981b74 374 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 32 358 3.0E-136 T 23-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 A3L08_04800 3dd7369ddda60383d3436dcd94981b74 374 ProSitePatterns PS01135 FtsZ protein signature 2. 127 148 - T 23-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 A3L08_04800 3dd7369ddda60383d3436dcd94981b74 374 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 43 203 1.4E-47 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A3L08_04800 3dd7369ddda60383d3436dcd94981b74 374 SUPERFAMILY SSF55307 233 347 2.52E-38 T 23-10-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 A3L08_04800 3dd7369ddda60383d3436dcd94981b74 374 ProSitePatterns PS01134 FtsZ protein signature 1. 74 108 - T 23-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 A3L08_04800 3dd7369ddda60383d3436dcd94981b74 374 SMART SM00865 236 352 3.4E-49 T 23-10-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-380320 A3L08_04800 3dd7369ddda60383d3436dcd94981b74 374 PRINTS PR00423 Cell division protein FtsZ signature 241 262 7.9E-44 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A3L08_04800 3dd7369ddda60383d3436dcd94981b74 374 PRINTS PR00423 Cell division protein FtsZ signature 218 240 7.9E-44 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A3L08_04800 3dd7369ddda60383d3436dcd94981b74 374 PRINTS PR00423 Cell division protein FtsZ signature 128 148 7.9E-44 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A3L08_04800 3dd7369ddda60383d3436dcd94981b74 374 PRINTS PR00423 Cell division protein FtsZ signature 156 177 7.9E-44 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A3L08_04800 3dd7369ddda60383d3436dcd94981b74 374 Gene3D G3DSA:3.40.50.1440 35 249 1.7E-83 T 23-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 A3L08_04800 3dd7369ddda60383d3436dcd94981b74 374 SMART SM00864 43 234 4.0E-108 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A3L08_04800 3dd7369ddda60383d3436dcd94981b74 374 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 39 374 38.338 T 23-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 A3L08_03210 0d344a5ad5f88a8fb1b8936a2201ed8a 277 Gene3D G3DSA:3.20.20.70 120 263 2.8E-91 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L08_03210 0d344a5ad5f88a8fb1b8936a2201ed8a 277 SUPERFAMILY SSF54675 5 103 4.94E-31 T 23-10-2018 A3L08_03210 0d344a5ad5f88a8fb1b8936a2201ed8a 277 TIGRFAM TIGR00078 nadC: nicotinate-nucleotide diphosphorylase (carboxylating) 7 273 5.0E-99 T 23-10-2018 IPR004393 Nicotinate-nucleotide pyrophosphorylase GO:0004514|GO:0019363 KEGG: 00760+2.4.2.19|MetaCyc: PWY-5316|MetaCyc: PWY-5653|MetaCyc: PWY-7342|Reactome: R-HSA-196807 A3L08_03210 0d344a5ad5f88a8fb1b8936a2201ed8a 277 SUPERFAMILY SSF51690 104 273 3.3E-49 T 23-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 A3L08_03210 0d344a5ad5f88a8fb1b8936a2201ed8a 277 Gene3D G3DSA:3.90.1170.20 10 271 2.8E-91 T 23-10-2018 IPR037128 Quinolinate phosphoribosyl transferase, N-terminal domain superfamily GO:0016763 Reactome: R-HSA-196807 A3L08_03210 0d344a5ad5f88a8fb1b8936a2201ed8a 277 PIRSF PIRSF006250 3 276 9.8E-94 T 23-10-2018 IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD Reactome: R-HSA-196807 A3L08_03210 0d344a5ad5f88a8fb1b8936a2201ed8a 277 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 16 102 8.0E-32 T 23-10-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 A3L08_03210 0d344a5ad5f88a8fb1b8936a2201ed8a 277 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 104 272 5.8E-51 T 23-10-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 Reactome: R-HSA-196807 A3L08_07985 a9c2960f5fc0c73b6cb082ab559d4a82 344 SUPERFAMILY SSF81345 5 339 2.48E-86 T 23-10-2018 IPR037294 ABC transporter, BtuC-like A3L08_07985 a9c2960f5fc0c73b6cb082ab559d4a82 344 Pfam PF01032 FecCD transport family 21 339 1.5E-97 T 23-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 A3L08_07985 a9c2960f5fc0c73b6cb082ab559d4a82 344 Gene3D G3DSA:1.10.3470.10 8 343 2.4E-105 T 23-10-2018 IPR037294 ABC transporter, BtuC-like A3L08_01260 0b3003f14f0bf33d63e5e4bdf4418816 239 SUPERFAMILY SSF75217 2 175 5.95E-31 T 23-10-2018 IPR029028 Alpha/beta knot methyltransferases A3L08_01260 0b3003f14f0bf33d63e5e4bdf4418816 239 Gene3D G3DSA:3.40.1280.10 1 157 1.2E-48 T 23-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal A3L08_01260 0b3003f14f0bf33d63e5e4bdf4418816 239 PIRSF PIRSF004808 1 236 4.6E-74 T 23-10-2018 IPR004384 RNA methyltransferase TrmJ/LasT GO:0006396|GO:0008173 A3L08_01260 0b3003f14f0bf33d63e5e4bdf4418816 239 TIGRFAM TIGR00050 rRNA_methyl_1: RNA methyltransferase, TrmH family, group 1 3 227 4.4E-63 T 23-10-2018 IPR004384 RNA methyltransferase TrmJ/LasT GO:0006396|GO:0008173 A3L08_01260 0b3003f14f0bf33d63e5e4bdf4418816 239 Pfam PF00588 SpoU rRNA Methylase family 4 151 7.6E-32 T 23-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 A3L08_02655 a5bfbd5ea7a45e83c2be1406847f8cfe 795 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 45 356 2.0E-17 T 23-10-2018 IPR000914 Solute-binding protein family 5 domain A3L08_02655 a5bfbd5ea7a45e83c2be1406847f8cfe 795 Gene3D G3DSA:3.10.105.10 168 396 6.4E-18 T 23-10-2018 A3L08_02655 a5bfbd5ea7a45e83c2be1406847f8cfe 795 SUPERFAMILY SSF53850 9 366 5.79E-21 T 23-10-2018 A3L08_01265 5991701670e23994803faff52d152486 179 ProDom PD068053 METHYLTRANSFERASE DNA METHYLATED-DNA--PROTEIN-CYSTEINE 6-O- O-6-METHYLGUANINE-DNA- REPAIR MGMT DAMAGE ALKYLTRANSFERASE METHYLGUANINE-DNA 1 96 2.0E-19 T 23-10-2018 IPR015236 Domain of unknown function DUF1938 GO:0005737 A3L08_01265 5991701670e23994803faff52d152486 179 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 139 145 - T 23-10-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 A3L08_01265 5991701670e23994803faff52d152486 179 SUPERFAMILY SSF53155 1 88 8.63E-26 T 23-10-2018 IPR036631 Methylated DNA-protein cysteine methyltransferase domain superfamily GO:0003908|GO:0006281 Reactome: R-HSA-5657655 A3L08_01265 5991701670e23994803faff52d152486 179 Gene3D G3DSA:3.30.160.70 1 88 8.5E-20 T 23-10-2018 A3L08_01265 5991701670e23994803faff52d152486 179 Gene3D G3DSA:1.10.10.10 89 174 4.5E-31 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L08_01265 5991701670e23994803faff52d152486 179 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 91 169 6.0E-23 T 23-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 A3L08_01265 5991701670e23994803faff52d152486 179 Pfam PF09153 Domain of unknown function (DUF1938) 1 85 2.1E-22 T 23-10-2018 IPR015236 Domain of unknown function DUF1938 GO:0005737 A3L08_01265 5991701670e23994803faff52d152486 179 SUPERFAMILY SSF46767 90 169 2.49E-21 T 23-10-2018 IPR036217 Methylated DNA-protein cysteine methyltransferase, DNA binding domain Reactome: R-HSA-5657655 A3L08_01265 5991701670e23994803faff52d152486 179 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 90 167 6.5E-25 T 23-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 A3L08_05225 fe51f804863804f60a4595ec82f10741 109 SUPERFAMILY SSF53146 6 106 3.01E-18 T 23-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily A3L08_05225 fe51f804863804f60a4595ec82f10741 109 Gene3D G3DSA:3.30.420.130 5 109 8.9E-18 T 23-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily A3L08_05225 fe51f804863804f60a4595ec82f10741 109 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 16 108 1.9E-11 T 23-10-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis A3L08_08785 3a6d3e9bb906a6fe5b0ee316712f2269 598 SUPERFAMILY SSF50447 466 593 4.2E-25 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily A3L08_08785 3a6d3e9bb906a6fe5b0ee316712f2269 598 Gene3D G3DSA:2.40.30.10 233 350 1.0E-40 T 23-10-2018 A3L08_08785 3a6d3e9bb906a6fe5b0ee316712f2269 598 Hamap MF_00100_A Translation initiation factor IF-2 [infB]. 3 597 43.655 T 23-10-2018 IPR004544 Translation initiation factor aIF-2, archaea GO:0003743|GO:0005525|GO:0005622|GO:0006413 A3L08_08785 3a6d3e9bb906a6fe5b0ee316712f2269 598 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 165 7.7E-21 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A3L08_08785 3a6d3e9bb906a6fe5b0ee316712f2269 598 Pfam PF11987 Translation-initiation factor 2 350 447 1.9E-23 T 23-10-2018 IPR023115 Translation initiation factor IF- 2, domain 3 A3L08_08785 3a6d3e9bb906a6fe5b0ee316712f2269 598 PRINTS PR00315 GTP-binding elongation factor signature 9 22 1.8E-10 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L08_08785 3a6d3e9bb906a6fe5b0ee316712f2269 598 PRINTS PR00315 GTP-binding elongation factor signature 75 85 1.8E-10 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L08_08785 3a6d3e9bb906a6fe5b0ee316712f2269 598 PRINTS PR00315 GTP-binding elongation factor signature 91 102 1.8E-10 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L08_08785 3a6d3e9bb906a6fe5b0ee316712f2269 598 PRINTS PR00315 GTP-binding elongation factor signature 127 136 1.8E-10 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L08_08785 3a6d3e9bb906a6fe5b0ee316712f2269 598 Pfam PF03144 Elongation factor Tu domain 2 248 326 3.6E-13 T 23-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 A3L08_08785 3a6d3e9bb906a6fe5b0ee316712f2269 598 Gene3D G3DSA:3.40.50.10050 351 458 2.5E-36 T 23-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily A3L08_08785 3a6d3e9bb906a6fe5b0ee316712f2269 598 SUPERFAMILY SSF52540 6 289 5.04E-54 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_08785 3a6d3e9bb906a6fe5b0ee316712f2269 598 Gene3D G3DSA:3.40.50.300 1 228 3.1E-65 T 23-10-2018 A3L08_08785 3a6d3e9bb906a6fe5b0ee316712f2269 598 Gene3D G3DSA:2.40.30.10 467 557 1.2E-30 T 23-10-2018 A3L08_08785 3a6d3e9bb906a6fe5b0ee316712f2269 598 Pfam PF00009 Elongation factor Tu GTP binding domain 9 215 7.8E-33 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A3L08_08785 3a6d3e9bb906a6fe5b0ee316712f2269 598 TIGRFAM TIGR00491 aIF-2: translation initiation factor aIF-2 4 595 1.9E-241 T 23-10-2018 IPR004544 Translation initiation factor aIF-2, archaea GO:0003743|GO:0005525|GO:0005622|GO:0006413 A3L08_08785 3a6d3e9bb906a6fe5b0ee316712f2269 598 Pfam PF14578 Elongation factor Tu domain 4 468 554 6.9E-29 T 23-10-2018 IPR029459 Elongation factor Tu-type domain A3L08_08785 3a6d3e9bb906a6fe5b0ee316712f2269 598 SUPERFAMILY SSF52156 335 461 1.57E-35 T 23-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily A3L08_01495 7686af1c5bc57661c760ec476852ff9a 261 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 1 205 4.2E-10 T 23-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain A3L08_01495 7686af1c5bc57661c760ec476852ff9a 261 Gene3D G3DSA:3.40.50.300 1 223 1.2E-36 T 23-10-2018 A3L08_01495 7686af1c5bc57661c760ec476852ff9a 261 SUPERFAMILY SSF52540 2 222 2.1E-31 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_09490 d2c6c5bcb29231797bc18b9174978a05 76 Pfam PF01775 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A 2 58 2.0E-11 T 23-10-2018 IPR023573 Ribosomal protein 50S-L18Ae/60S-L20/60S-L18A GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_09490 d2c6c5bcb29231797bc18b9174978a05 76 SUPERFAMILY SSF160374 1 74 9.94E-24 T 23-10-2018 A3L08_09490 d2c6c5bcb29231797bc18b9174978a05 76 Hamap MF_00273 50S ribosomal protein L18Ae [rpl18a]. 3 58 18.063 T 23-10-2018 IPR028877 50S ribosomal protein L18Ae/60S ribosomal protein L20 and L18a Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_09490 d2c6c5bcb29231797bc18b9174978a05 76 ProDom PD010302 RIBOSOMAL LX 50S RIBONUCLEOPROTEIN HL32 DIRECT SEQUENCING LXA LSU 6 53 9.0E-14 T 23-10-2018 IPR002768 50S ribosomal protein L18Ae, archaea GO:0003735|GO:0005840|GO:0006412 A3L08_09490 d2c6c5bcb29231797bc18b9174978a05 76 Gene3D G3DSA:3.10.20.10 3 75 1.6E-25 T 23-10-2018 A3L08_00170 ca5e02fbe763271af6fcdeeb4e0e3c08 256 Pfam PF13614 AAA domain 4 178 9.3E-55 T 23-10-2018 IPR025669 AAA domain A3L08_00170 ca5e02fbe763271af6fcdeeb4e0e3c08 256 Gene3D G3DSA:3.40.50.300 1 255 1.2E-74 T 23-10-2018 A3L08_00170 ca5e02fbe763271af6fcdeeb4e0e3c08 256 PIRSF PIRSF009320 91 256 3.5E-5 T 23-10-2018 A3L08_00170 ca5e02fbe763271af6fcdeeb4e0e3c08 256 PIRSF PIRSF009320 2 83 2.6E-15 T 23-10-2018 A3L08_00170 ca5e02fbe763271af6fcdeeb4e0e3c08 256 SUPERFAMILY SSF52540 1 254 2.74E-60 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_07090 51467c241897dc663f896f29805cdedf 339 Pfam PF05343 M42 glutamyl aminopeptidase 48 328 8.4E-70 T 23-10-2018 IPR008007 Peptidase M42 A3L08_07090 51467c241897dc663f896f29805cdedf 339 SUPERFAMILY SSF53187 2 335 1.64E-48 T 23-10-2018 A3L08_07090 51467c241897dc663f896f29805cdedf 339 PIRSF PIRSF001123 1 337 1.4E-37 T 23-10-2018 IPR008007 Peptidase M42 A3L08_07090 51467c241897dc663f896f29805cdedf 339 SUPERFAMILY SSF101821 67 178 1.98E-25 T 23-10-2018 A3L08_07090 51467c241897dc663f896f29805cdedf 339 Gene3D G3DSA:2.40.30.40 70 164 1.4E-111 T 23-10-2018 IPR023367 Peptidase M42, domain 2 A3L08_07090 51467c241897dc663f896f29805cdedf 339 Gene3D G3DSA:3.40.630.10 11 333 1.4E-111 T 23-10-2018 A3L08_02270 42c7bfcb3938b12d3af3b3b00753af4d 102 SUPERFAMILY SSF46785 6 95 2.33E-17 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L08_02270 42c7bfcb3938b12d3af3b3b00753af4d 102 Gene3D G3DSA:1.10.10.10 1 99 4.9E-26 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L08_02270 42c7bfcb3938b12d3af3b3b00753af4d 102 SMART SM00418 8 79 0.0034 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L08_02270 42c7bfcb3938b12d3af3b3b00753af4d 102 Pfam PF13601 Winged helix DNA-binding domain 18 94 1.5E-20 T 23-10-2018 IPR027395 Winged helix DNA-binding domain A3L08_05875 55d8df07512d350e85f106351be557dc 70 SUPERFAMILY SSF50249 9 69 3.83E-16 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L08_05875 55d8df07512d350e85f106351be557dc 70 Pfam PF01938 TRAM domain 13 69 4.1E-15 T 23-10-2018 IPR002792 TRAM domain A3L08_05875 55d8df07512d350e85f106351be557dc 70 Gene3D G3DSA:2.40.50.140 4 69 1.3E-26 T 23-10-2018 A3L08_04415 614d8c3805056a0dc8f752facfcfa1bd 374 TIGRFAM TIGR02151 IPP_isom_2: isopentenyl-diphosphate delta-isomerase, type 2 13 352 5.3E-131 T 23-10-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 A3L08_04415 614d8c3805056a0dc8f752facfcfa1bd 374 PIRSF PIRSF003314 7 363 8.3E-133 T 23-10-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 A3L08_04415 614d8c3805056a0dc8f752facfcfa1bd 374 Hamap MF_00354 Isopentenyl-diphosphate delta-isomerase [fni]. 10 353 41.199 T 23-10-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 A3L08_04415 614d8c3805056a0dc8f752facfcfa1bd 374 SMART SM01240 30 349 0.0012 T 23-10-2018 A3L08_04415 614d8c3805056a0dc8f752facfcfa1bd 374 Gene3D G3DSA:3.20.20.70 10 373 2.7E-128 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L08_04415 614d8c3805056a0dc8f752facfcfa1bd 374 SUPERFAMILY SSF51395 32 365 1.41E-79 T 23-10-2018 A3L08_04415 614d8c3805056a0dc8f752facfcfa1bd 374 Pfam PF01070 FMN-dependent dehydrogenase 13 346 1.1E-24 T 23-10-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 Reactome: R-HSA-9033241 A3L08_07445 1f09b6ee4b63fd343aa0f7679cd65f40 136 SMART SM00116 79 126 1.2E-7 T 23-10-2018 IPR000644 CBS domain A3L08_07445 1f09b6ee4b63fd343aa0f7679cd65f40 136 SMART SM00116 14 62 7.8E-9 T 23-10-2018 IPR000644 CBS domain A3L08_07445 1f09b6ee4b63fd343aa0f7679cd65f40 136 Gene3D G3DSA:3.10.580.10 1 136 8.4E-45 T 23-10-2018 A3L08_07445 1f09b6ee4b63fd343aa0f7679cd65f40 136 SUPERFAMILY SSF54631 7 128 3.16E-32 T 23-10-2018 A3L08_07445 1f09b6ee4b63fd343aa0f7679cd65f40 136 Pfam PF00571 CBS domain 10 61 2.7E-10 T 23-10-2018 IPR000644 CBS domain A3L08_07445 1f09b6ee4b63fd343aa0f7679cd65f40 136 Pfam PF00571 CBS domain 72 124 3.7E-14 T 23-10-2018 IPR000644 CBS domain A3L08_03365 540936b6fdf51b3a4c663c8b97aac26e 98 Pfam PF01282 Ribosomal protein S24e 21 97 6.4E-28 T 23-10-2018 IPR001976 Ribosomal protein S24e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_03365 540936b6fdf51b3a4c663c8b97aac26e 98 SUPERFAMILY SSF54189 1 97 6.47E-33 T 23-10-2018 IPR012678 Ribosomal protein L23/L15e core domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L08_03365 540936b6fdf51b3a4c663c8b97aac26e 98 Hamap MF_00545 30S ribosomal protein S24e [rps24e]. 1 98 21.556 T 23-10-2018 IPR001976 Ribosomal protein S24e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_03365 540936b6fdf51b3a4c663c8b97aac26e 98 ProSitePatterns PS00529 Ribosomal protein S24e signature. 60 82 - T 23-10-2018 IPR018098 Ribosomal S24e conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_03365 540936b6fdf51b3a4c663c8b97aac26e 98 Gene3D G3DSA:3.30.70.330 1 98 2.3E-39 T 23-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily A3L08_03365 540936b6fdf51b3a4c663c8b97aac26e 98 ProDom PD006052 RIBOSOMAL S24 40S RIBONUCLEOPROTEIN S24E 30S S24 CDNA RIKEN ACETYLATION 11 76 3.0E-28 T 23-10-2018 IPR001976 Ribosomal protein S24e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_03845 241033c7469ae5dcfaa8c97c1eee1643 260 TIGRFAM TIGR03633 arc_protsome_A: proteasome endopeptidase complex, archaeal, alpha subunit 8 234 5.8E-106 T 23-10-2018 IPR019982 Proteasome alpha subunit, archaeal GO:0004298|GO:0005839|GO:0051603 A3L08_03845 241033c7469ae5dcfaa8c97c1eee1643 260 ProSitePatterns PS00388 Proteasome alpha-type subunits signature. 10 32 - T 23-10-2018 IPR000426 Proteasome alpha-subunit, N-terminal domain GO:0004175|GO:0006511|GO:0019773 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 A3L08_03845 241033c7469ae5dcfaa8c97c1eee1643 260 Pfam PF00227 Proteasome subunit 33 215 1.5E-65 T 23-10-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 A3L08_03845 241033c7469ae5dcfaa8c97c1eee1643 260 SUPERFAMILY SSF56235 7 241 4.48E-83 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A3L08_03845 241033c7469ae5dcfaa8c97c1eee1643 260 Hamap MF_00289_A Proteasome subunit alpha [prcA]. 5 234 47.532 T 23-10-2018 IPR019982 Proteasome alpha subunit, archaeal GO:0004298|GO:0005839|GO:0051603 A3L08_03845 241033c7469ae5dcfaa8c97c1eee1643 260 Pfam PF10584 Proteasome subunit A N-terminal signature 10 32 4.0E-12 T 23-10-2018 IPR000426 Proteasome alpha-subunit, N-terminal domain GO:0004175|GO:0006511|GO:0019773 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 A3L08_03845 241033c7469ae5dcfaa8c97c1eee1643 260 SMART SM00948 10 32 3.4E-10 T 23-10-2018 IPR000426 Proteasome alpha-subunit, N-terminal domain GO:0004175|GO:0006511|GO:0019773 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 A3L08_03845 241033c7469ae5dcfaa8c97c1eee1643 260 Gene3D G3DSA:3.60.20.10 5 253 1.7E-92 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A3L08_04510 1cb77a094cdcdc529052850d624a0f6a 105 SUPERFAMILY SSF54913 1 104 5.4E-35 T 23-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta A3L08_04510 1cb77a094cdcdc529052850d624a0f6a 105 Gene3D G3DSA:3.30.70.120 1 104 2.3E-37 T 23-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal A3L08_04510 1cb77a094cdcdc529052850d624a0f6a 105 PRINTS PR00340 P-II protein signature 2 17 5.9E-24 T 23-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 A3L08_04510 1cb77a094cdcdc529052850d624a0f6a 105 PRINTS PR00340 P-II protein signature 75 95 5.9E-24 T 23-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 A3L08_04510 1cb77a094cdcdc529052850d624a0f6a 105 PRINTS PR00340 P-II protein signature 44 67 5.9E-24 T 23-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 A3L08_04510 1cb77a094cdcdc529052850d624a0f6a 105 SMART SM00938 4 97 2.9E-42 T 23-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 A3L08_04510 1cb77a094cdcdc529052850d624a0f6a 105 Pfam PF00543 Nitrogen regulatory protein P-II 4 97 1.5E-28 T 23-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 A3L08_09760 69bc7ac8d31ebfde70989fe8a718ae05 124 PIRSF PIRSF004878 1 117 5.2E-42 T 23-10-2018 IPR016432 Ribonuclease P, protein component 4 GO:0001682|GO:0004526 A3L08_09760 69bc7ac8d31ebfde70989fe8a718ae05 124 Pfam PF04032 RNAse P Rpr2/Rpp21/SNM1 subunit domain 22 101 2.4E-16 T 23-10-2018 IPR007175 RNAse P, Rpr2/Rpp21 subunit Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 A3L08_09760 69bc7ac8d31ebfde70989fe8a718ae05 124 Gene3D G3DSA:2.20.25.200 65 120 2.3E-23 T 23-10-2018 A3L08_09760 69bc7ac8d31ebfde70989fe8a718ae05 124 Hamap MF_00757 Ribonuclease P protein component 4 [rnp4]. 11 110 25.586 T 23-10-2018 IPR016432 Ribonuclease P, protein component 4 GO:0001682|GO:0004526 A3L08_09760 69bc7ac8d31ebfde70989fe8a718ae05 124 Gene3D G3DSA:1.20.5.420 6 64 2.0E-21 T 23-10-2018 A3L08_07830 6bffffb31e806d6e4cddff87523e82fb 126 Gene3D G3DSA:3.30.70.120 1 126 1.6E-57 T 23-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal A3L08_07830 6bffffb31e806d6e4cddff87523e82fb 126 Pfam PF02641 Uncharacterized ACR, COG1993 11 104 4.3E-39 T 23-10-2018 IPR003793 Domain of unknown function DUF190 A3L08_07830 6bffffb31e806d6e4cddff87523e82fb 126 SUPERFAMILY SSF54913 8 106 2.8E-34 T 23-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta A3L08_08635 935eba74be91cc4badb53628b29bd122 496 Gene3D G3DSA:1.20.1720.10 18 223 1.9E-45 T 23-10-2018 A3L08_08635 935eba74be91cc4badb53628b29bd122 496 Gene3D G3DSA:1.20.1250.20 269 477 2.1E-17 T 23-10-2018 A3L08_08635 935eba74be91cc4badb53628b29bd122 496 Pfam PF07690 Major Facilitator Superfamily 26 419 5.5E-49 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A3L08_08635 935eba74be91cc4badb53628b29bd122 496 SUPERFAMILY SSF103473 15 489 2.35E-67 T 23-10-2018 IPR036259 MFS transporter superfamily A3L08_09790 207446849e5f722741e6a64d8f2c9dfc 94 Pfam PF01402 Ribbon-helix-helix protein, copG family 7 45 1.4E-7 T 23-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 A3L08_09790 207446849e5f722741e6a64d8f2c9dfc 94 Gene3D G3DSA:1.10.1220.10 11 47 3.1E-9 T 23-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 A3L08_09790 207446849e5f722741e6a64d8f2c9dfc 94 SUPERFAMILY SSF47598 5 47 2.45E-10 T 23-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 A3L08_02560 b60b2d1caac88b30b73c04db3c082227 507 Gene3D G3DSA:1.20.1640.10 313 501 6.4E-14 T 23-10-2018 A3L08_02560 b60b2d1caac88b30b73c04db3c082227 507 Gene3D G3DSA:3.30.70.3400 35 117 5.4E-10 T 23-10-2018 A3L08_02560 b60b2d1caac88b30b73c04db3c082227 507 Hamap MF_01463_A Protein translocase subunit SecD [secD]. 6 506 18.98 T 23-10-2018 IPR024912 Protein translocase subunit SecD, archaeal A3L08_02560 b60b2d1caac88b30b73c04db3c082227 507 SUPERFAMILY SSF82866 299 492 2.35E-27 T 23-10-2018 A3L08_02560 b60b2d1caac88b30b73c04db3c082227 507 Pfam PF02355 Protein export membrane protein 330 490 1.6E-18 T 23-10-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial A3L08_01245 81810f75b89f52a03eaf7a658360270f 304 Gene3D G3DSA:3.40.50.720 7 298 6.7E-136 T 23-10-2018 A3L08_01245 81810f75b89f52a03eaf7a658360270f 304 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 219 235 - T 23-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site A3L08_01245 81810f75b89f52a03eaf7a658360270f 304 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 142 169 - T 23-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 A3L08_01245 81810f75b89f52a03eaf7a658360270f 304 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 190 212 - T 23-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site A3L08_01245 81810f75b89f52a03eaf7a658360270f 304 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 3 303 1.1E-39 T 23-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 A3L08_01245 81810f75b89f52a03eaf7a658360270f 304 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 105 280 7.6E-73 T 23-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 A3L08_01245 81810f75b89f52a03eaf7a658360270f 304 SUPERFAMILY SSF51735 99 281 1.8E-67 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L08_01245 81810f75b89f52a03eaf7a658360270f 304 SUPERFAMILY SSF52283 2 133 1.81E-39 T 23-10-2018 A3L08_01245 81810f75b89f52a03eaf7a658360270f 304 Gene3D G3DSA:3.40.50.720 92 282 6.7E-136 T 23-10-2018 A3L08_06105 4323782323d1c1c021d862422e9ae654 240 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 236 3.4E-57 T 23-10-2018 A3L08_06105 4323782323d1c1c021d862422e9ae654 240 SUPERFAMILY SSF51735 5 239 2.1E-76 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L08_06105 4323782323d1c1c021d862422e9ae654 240 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 23-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A3L08_06105 4323782323d1c1c021d862422e9ae654 240 Gene3D G3DSA:3.40.50.720 1 239 7.9E-79 T 23-10-2018 A3L08_06105 4323782323d1c1c021d862422e9ae654 240 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 4.8E-14 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L08_06105 4323782323d1c1c021d862422e9ae654 240 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 4.8E-14 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L08_06105 4323782323d1c1c021d862422e9ae654 240 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 4.8E-14 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L08_06105 4323782323d1c1c021d862422e9ae654 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 2.3E-41 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L08_06105 4323782323d1c1c021d862422e9ae654 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 203 223 2.3E-41 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L08_06105 4323782323d1c1c021d862422e9ae654 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 2.3E-41 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L08_06105 4323782323d1c1c021d862422e9ae654 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 2.3E-41 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L08_06105 4323782323d1c1c021d862422e9ae654 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 2.3E-41 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L08_06105 4323782323d1c1c021d862422e9ae654 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 2.3E-41 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L08_06105 4323782323d1c1c021d862422e9ae654 240 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 170 0.0043 T 23-10-2018 A3L08_05155 6b226708c5bf428dd37e035d9f259169 204 Gene3D G3DSA:1.10.1760.20 1 196 5.1E-63 T 23-10-2018 A3L08_05155 6b226708c5bf428dd37e035d9f259169 204 Pfam PF01891 Cobalt uptake substrate-specific transmembrane region 2 194 2.0E-60 T 23-10-2018 IPR002751 Metal transport protein CbiM/NikMN GO:0000041|GO:0016021 A3L08_06750 b5313f72c5cec91708d0648cb18a66e6 162 Pfam PF02643 Uncharacterized ACR, COG1430 15 114 1.5E-17 T 23-10-2018 IPR003795 Protein of unknown function DUF192 A3L08_06750 b5313f72c5cec91708d0648cb18a66e6 162 Gene3D G3DSA:2.60.120.1140 1 123 1.4E-12 T 23-10-2018 IPR038695 Saro_0823-like superfamily A3L08_06750 b5313f72c5cec91708d0648cb18a66e6 162 Hamap MF_00263 UPF0127 protein . 2 116 28.332 T 23-10-2018 IPR022906 Uncharacterised protein family UPF0127 A3L08_01450 2caae2c4d72307dccc7da3b76f100c66 315 SUPERFAMILY SSF53633 1 313 2.49E-87 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily A3L08_01450 2caae2c4d72307dccc7da3b76f100c66 315 Pfam PF00696 Amino acid kinase family 2 296 2.2E-30 T 23-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 A3L08_01450 2caae2c4d72307dccc7da3b76f100c66 315 TIGRFAM TIGR00746 arcC: carbamate kinase 2 313 5.0E-144 T 23-10-2018 IPR003964 Carbamate kinase GO:0006525|GO:0008804 KEGG: 00220+2.7.2.2|KEGG: 00230+2.7.2.2|KEGG: 00910+2.7.2.2 A3L08_01450 2caae2c4d72307dccc7da3b76f100c66 315 PRINTS PR01469 Bacterial carbamate kinase signature 214 229 1.1E-67 T 23-10-2018 A3L08_01450 2caae2c4d72307dccc7da3b76f100c66 315 PRINTS PR01469 Bacterial carbamate kinase signature 184 202 1.1E-67 T 23-10-2018 A3L08_01450 2caae2c4d72307dccc7da3b76f100c66 315 PRINTS PR01469 Bacterial carbamate kinase signature 44 63 1.1E-67 T 23-10-2018 A3L08_01450 2caae2c4d72307dccc7da3b76f100c66 315 PRINTS PR01469 Bacterial carbamate kinase signature 77 95 1.1E-67 T 23-10-2018 A3L08_01450 2caae2c4d72307dccc7da3b76f100c66 315 PRINTS PR01469 Bacterial carbamate kinase signature 161 180 1.1E-67 T 23-10-2018 A3L08_01450 2caae2c4d72307dccc7da3b76f100c66 315 PRINTS PR01469 Bacterial carbamate kinase signature 269 284 1.1E-67 T 23-10-2018 A3L08_01450 2caae2c4d72307dccc7da3b76f100c66 315 PRINTS PR01469 Bacterial carbamate kinase signature 112 131 1.1E-67 T 23-10-2018 A3L08_01450 2caae2c4d72307dccc7da3b76f100c66 315 PIRSF PIRSF000723 1 314 3.7E-140 T 23-10-2018 IPR003964 Carbamate kinase GO:0006525|GO:0008804 KEGG: 00220+2.7.2.2|KEGG: 00230+2.7.2.2|KEGG: 00910+2.7.2.2 A3L08_01450 2caae2c4d72307dccc7da3b76f100c66 315 Gene3D G3DSA:3.40.1160.10 1 314 2.9E-136 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily A3L08_05660 971934b7d2303528cd1092308edd76a4 464 Pfam PF04851 Type III restriction enzyme, res subunit 93 231 2.9E-17 T 23-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 A3L08_05660 971934b7d2303528cd1092308edd76a4 464 Gene3D G3DSA:3.40.50.300 84 261 1.9E-34 T 23-10-2018 A3L08_05660 971934b7d2303528cd1092308edd76a4 464 SMART SM00490 328 406 3.2E-13 T 23-10-2018 IPR001650 Helicase, C-terminal A3L08_05660 971934b7d2303528cd1092308edd76a4 464 Gene3D G3DSA:3.40.50.300 275 455 2.6E-32 T 23-10-2018 A3L08_05660 971934b7d2303528cd1092308edd76a4 464 SMART SM00487 91 262 4.0E-27 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A3L08_05660 971934b7d2303528cd1092308edd76a4 464 SUPERFAMILY SSF52540 136 419 1.07E-34 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_05660 971934b7d2303528cd1092308edd76a4 464 Pfam PF00271 Helicase conserved C-terminal domain 306 404 2.7E-11 T 23-10-2018 IPR001650 Helicase, C-terminal A3L08_01320 abbdf0ce1f0dd2031ed0bd7f0cc02460 311 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 72 218 1.1E-20 T 23-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 A3L08_01320 abbdf0ce1f0dd2031ed0bd7f0cc02460 311 SUPERFAMILY SSF52518 17 309 1.53E-72 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold A3L08_01320 abbdf0ce1f0dd2031ed0bd7f0cc02460 311 Gene3D G3DSA:3.40.50.970 96 310 1.3E-70 T 23-10-2018 A3L08_06545 2ec7c930c3f54889162a9c929abe596e 89 Pfam PF04066 Multiple resistance and pH regulation protein F (MrpF / PhaF) 32 82 1.8E-5 T 23-10-2018 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 A3L08_04790 8b246c8866ba625446155c1445acbdb5 329 Pfam PF16868 NMT1-like family 38 320 3.5E-88 T 23-10-2018 IPR011852 TRAP transporter solute receptor, TAXI family A3L08_04790 8b246c8866ba625446155c1445acbdb5 329 TIGRFAM TIGR02122 TRAP_TAXI: TRAP transporter solute receptor, TAXI family 8 320 6.1E-102 T 23-10-2018 IPR011852 TRAP transporter solute receptor, TAXI family A3L08_04790 8b246c8866ba625446155c1445acbdb5 329 Gene3D G3DSA:3.40.190.10 38 320 4.5E-102 T 23-10-2018 A3L08_04790 8b246c8866ba625446155c1445acbdb5 329 Gene3D G3DSA:3.40.190.10 120 257 4.5E-102 T 23-10-2018 A3L08_04790 8b246c8866ba625446155c1445acbdb5 329 SUPERFAMILY SSF53850 34 321 3.15E-77 T 23-10-2018 A3L08_00545 ae6c74935597f5eeb12645cfedc4cc2e 428 Gene3D G3DSA:3.30.420.220 1 125 3.6E-48 T 23-10-2018 A3L08_00545 ae6c74935597f5eeb12645cfedc4cc2e 428 SUPERFAMILY SSF89124 126 365 5.75E-79 T 23-10-2018 IPR036070 Nop domain superfamily A3L08_00545 ae6c74935597f5eeb12645cfedc4cc2e 428 Gene3D G3DSA:1.10.287.660 131 243 3.2E-37 T 23-10-2018 IPR029012 Helix hairpin bin domain superfamily A3L08_00545 ae6c74935597f5eeb12645cfedc4cc2e 428 SMART SM00931 130 182 3.3E-26 T 23-10-2018 IPR012976 NOSIC A3L08_00545 ae6c74935597f5eeb12645cfedc4cc2e 428 Gene3D G3DSA:1.10.150.460 161 212 3.2E-37 T 23-10-2018 A3L08_00545 ae6c74935597f5eeb12645cfedc4cc2e 428 Pfam PF01798 snoRNA binding domain, fibrillarin 138 363 6.3E-71 T 23-10-2018 IPR002687 Nop domain A3L08_00545 ae6c74935597f5eeb12645cfedc4cc2e 428 Gene3D G3DSA:1.10.246.90 244 368 6.6E-52 T 23-10-2018 A3L08_05685 57f674a989b41465f11ce69d8b5da016 247 Gene3D G3DSA:3.40.50.300 2 241 1.7E-47 T 23-10-2018 A3L08_05685 57f674a989b41465f11ce69d8b5da016 247 SUPERFAMILY SSF52540 2 244 7.24E-48 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_05685 57f674a989b41465f11ce69d8b5da016 247 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 3 221 5.5E-20 T 23-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain A3L08_07100 565973459b90ad9bdbaf29215aee16e4 136 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 57 72 2.0E-7 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L08_07100 565973459b90ad9bdbaf29215aee16e4 136 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 89 104 2.0E-7 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L08_07100 565973459b90ad9bdbaf29215aee16e4 136 Gene3D G3DSA:1.10.10.10 36 124 5.4E-18 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L08_07100 565973459b90ad9bdbaf29215aee16e4 136 SMART SM00418 55 133 2.3E-8 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L08_07100 565973459b90ad9bdbaf29215aee16e4 136 Pfam PF01022 Bacterial regulatory protein, arsR family 62 108 6.7E-12 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L08_07100 565973459b90ad9bdbaf29215aee16e4 136 SUPERFAMILY SSF46785 49 122 9.29E-16 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L08_07295 cac239d9b5d4154875611bed739bf12c 383 Gene3D G3DSA:3.40.50.150 42 236 5.2E-26 T 23-10-2018 A3L08_07295 cac239d9b5d4154875611bed739bf12c 383 Pfam PF13847 Methyltransferase domain 86 151 3.8E-7 T 23-10-2018 IPR025714 Methyltransferase domain A3L08_07295 cac239d9b5d4154875611bed739bf12c 383 SUPERFAMILY SSF53335 18 160 1.63E-20 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L08_08380 50a7288aed4c521bfad9018c470d26ba 174 Gene3D G3DSA:1.20.1260.10 1 152 2.1E-31 T 23-10-2018 IPR012347 Ferritin-like A3L08_08380 50a7288aed4c521bfad9018c470d26ba 174 SUPERFAMILY SSF47240 4 153 4.51E-20 T 23-10-2018 IPR009078 Ferritin-like superfamily A3L08_08380 50a7288aed4c521bfad9018c470d26ba 174 Pfam PF02915 Rubrerythrin 7 147 2.1E-14 T 23-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 A3L08_05765 087a7349ec6b5e3e5ae4f570efc30313 348 Gene3D G3DSA:3.20.20.70 63 286 1.1E-36 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L08_05765 087a7349ec6b5e3e5ae4f570efc30313 348 Pfam PF13353 4Fe-4S single cluster domain 73 172 7.8E-7 T 23-10-2018 A3L08_05765 087a7349ec6b5e3e5ae4f570efc30313 348 Pfam PF04055 Radical SAM superfamily 78 234 9.0E-23 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L08_05765 087a7349ec6b5e3e5ae4f570efc30313 348 PIRSF PIRSF004869 1 313 5.8E-99 T 23-10-2018 IPR016431 Pyruvate-formate lyase-activating enzyme, predicted A3L08_05765 087a7349ec6b5e3e5ae4f570efc30313 348 TIGRFAM TIGR04337 AmmeMemoSam_rS: AmmeMemoRadiSam system radical SAM enzyme 5 345 1.8E-111 T 23-10-2018 IPR027596 AmmeMemoRadiSam system radical SAM enzyme A3L08_05765 087a7349ec6b5e3e5ae4f570efc30313 348 SUPERFAMILY SSF102114 58 315 1.14E-36 T 23-10-2018 A3L08_05150 f34de9c22e84e342ea3c637478a592db 267 Gene3D G3DSA:3.40.50.10900 1 244 1.0E-73 T 23-10-2018 IPR038389 Proteasome assembly chaperone 2 superfamily A3L08_05150 f34de9c22e84e342ea3c637478a592db 267 SUPERFAMILY SSF159659 2 258 2.75E-44 T 23-10-2018 A3L08_05150 f34de9c22e84e342ea3c637478a592db 267 TIGRFAM TIGR00162 TIGR00162: TIGR00162 family protein 9 264 5.2E-74 T 23-10-2018 IPR004426 Conserved hypothetical protein CHP00062 A3L08_05150 f34de9c22e84e342ea3c637478a592db 267 Pfam PF09754 PAC2 family 19 242 1.5E-46 T 23-10-2018 IPR019151 Proteasome assembly chaperone 2 A3L08_01485 bae7cce117f07869fef6d2b04a2a5a01 417 Gene3D G3DSA:3.40.1350.30 112 257 1.5E-115 T 23-10-2018 A3L08_01485 bae7cce117f07869fef6d2b04a2a5a01 417 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 238 414 1.7E-21 T 23-10-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 A3L08_01485 bae7cce117f07869fef6d2b04a2a5a01 417 SUPERFAMILY SSF50249 4 58 1.26E-8 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L08_01485 bae7cce117f07869fef6d2b04a2a5a01 417 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 398 408 - T 23-10-2018 IPR030391 RNA methyltransferase TrmA, conserved site A3L08_01485 bae7cce117f07869fef6d2b04a2a5a01 417 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 347 378 - T 23-10-2018 IPR030390 RNA methyltransferase TrmA, active site A3L08_01485 bae7cce117f07869fef6d2b04a2a5a01 417 Gene3D G3DSA:3.40.50.150 73 410 1.5E-115 T 23-10-2018 A3L08_01485 bae7cce117f07869fef6d2b04a2a5a01 417 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 8 408 1.8E-84 T 23-10-2018 A3L08_01485 bae7cce117f07869fef6d2b04a2a5a01 417 SUPERFAMILY SSF53335 60 413 2.91E-70 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L08_01485 bae7cce117f07869fef6d2b04a2a5a01 417 Gene3D G3DSA:2.40.50.140 2 71 4.4E-15 T 23-10-2018 A3L08_02810 d700beffa05fa5f8612d8a269158ea4a 416 Gene3D G3DSA:1.10.3720.10 169 403 6.6E-47 T 23-10-2018 IPR035906 MetI-like superfamily A3L08_02810 d700beffa05fa5f8612d8a269158ea4a 416 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 242 402 4.3E-15 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A3L08_02810 d700beffa05fa5f8612d8a269158ea4a 416 Gene3D G3DSA:1.10.3720.10 2 82 3.1E-7 T 23-10-2018 IPR035906 MetI-like superfamily A3L08_02810 d700beffa05fa5f8612d8a269158ea4a 416 SUPERFAMILY SSF161098 8 68 1.01E-5 T 23-10-2018 IPR035906 MetI-like superfamily A3L08_02810 d700beffa05fa5f8612d8a269158ea4a 416 SUPERFAMILY SSF161098 179 415 5.23E-53 T 23-10-2018 IPR035906 MetI-like superfamily A3L08_01745 74000ec070c58284a393391a1fbd0071 123 TIGRFAM TIGR01300 CPA3_mnhG_phaG: monovalent cation/proton antiporter, MnhG/PhaG subunit 11 114 1.5E-34 T 23-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 A3L08_01745 74000ec070c58284a393391a1fbd0071 123 Pfam PF03334 Na+/H+ antiporter subunit 11 100 2.7E-23 T 23-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 A3L08_03490 1ea92d11899b97ce005ba8aafc5838e1 119 SUPERFAMILY SSF46785 15 114 2.73E-24 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L08_03490 1ea92d11899b97ce005ba8aafc5838e1 119 Gene3D G3DSA:1.10.10.10 4 117 1.1E-28 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L08_03490 1ea92d11899b97ce005ba8aafc5838e1 119 Pfam PF03551 Transcriptional regulator PadR-like family 26 99 3.9E-23 T 23-10-2018 IPR005149 Transcription regulator PadR, N-terminal A3L08_07055 48cea21bd378994ac255534f9ac38fb7 282 Pfam PF01937 Protein of unknown function DUF89 4 277 8.4E-54 T 23-10-2018 IPR002791 Domain of unknown function DUF89 A3L08_07055 48cea21bd378994ac255534f9ac38fb7 282 Gene3D G3DSA:1.10.8.380 1 67 7.7E-27 T 23-10-2018 A3L08_07055 48cea21bd378994ac255534f9ac38fb7 282 Gene3D G3DSA:3.40.50.10880 132 282 2.6E-60 T 23-10-2018 A3L08_07055 48cea21bd378994ac255534f9ac38fb7 282 PIRSF PIRSF006593 1 282 1.1E-100 T 23-10-2018 IPR014444 Uncharacterised conserved protein UCP006593 A3L08_07055 48cea21bd378994ac255534f9ac38fb7 282 SUPERFAMILY SSF111321 1 281 2.22E-83 T 23-10-2018 IPR036075 AF1104-like superfamily A3L08_07055 48cea21bd378994ac255534f9ac38fb7 282 Gene3D G3DSA:1.10.285.20 68 131 2.0E-20 T 23-10-2018 A3L08_08260 852608a1a272de550a44759cfdd336a5 119 SUPERFAMILY SSF117916 17 58 3.04E-5 T 23-10-2018 IPR034904 Fe-S cluster assembly domain superfamily A3L08_08260 852608a1a272de550a44759cfdd336a5 119 Pfam PF01883 Iron-sulfur cluster assembly protein 17 53 2.0E-5 T 23-10-2018 IPR002744 MIP18 family-like A3L08_01255 900494d068c85d90d1093c09ca793c91 304 SUPERFAMILY SSF51735 1 148 3.94E-21 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L08_01255 900494d068c85d90d1093c09ca793c91 304 Gene3D G3DSA:3.40.50.720 1 171 1.1E-64 T 23-10-2018 A3L08_01255 900494d068c85d90d1093c09ca793c91 304 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 172 295 3.6E-31 T 23-10-2018 IPR013752 Ketopantoate reductase, C-terminal domain A3L08_01255 900494d068c85d90d1093c09ca793c91 304 Pfam PF02558 Ketopantoate reductase PanE/ApbA 3 146 2.5E-38 T 23-10-2018 IPR013332 Ketopantoate reductase, N-terminal domain A3L08_01255 900494d068c85d90d1093c09ca793c91 304 SUPERFAMILY SSF48179 172 295 1.73E-28 T 23-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 A3L08_01255 900494d068c85d90d1093c09ca793c91 304 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 2 296 6.9E-82 T 23-10-2018 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0008677|GO:0015940 KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 A3L08_01255 900494d068c85d90d1093c09ca793c91 304 Gene3D G3DSA:1.10.1040.10 172 296 3.1E-41 T 23-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A3L08_02180 bce76f0a07710244743a96a96204f267 619 SMART SM00382 352 517 0.0066 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L08_02180 bce76f0a07710244743a96a96204f267 619 Pfam PF00437 Type II/IV secretion system protein 225 479 1.8E-64 T 23-10-2018 IPR001482 Type II/IV secretion system protein A3L08_02180 bce76f0a07710244743a96a96204f267 619 Gene3D G3DSA:3.40.50.300 320 607 1.2E-101 T 23-10-2018 A3L08_02180 bce76f0a07710244743a96a96204f267 619 Gene3D G3DSA:3.30.450.380 102 319 2.2E-66 T 23-10-2018 A3L08_02180 bce76f0a07710244743a96a96204f267 619 SUPERFAMILY SSF52540 205 525 1.0E-56 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_05070 cb41d71ba11feddc8138b6bdae0be070 372 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 6 322 7.1E-49 T 23-10-2018 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 A3L08_05070 cb41d71ba11feddc8138b6bdae0be070 372 SUPERFAMILY SSF53649 1 359 5.67E-75 T 23-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 A3L08_05070 cb41d71ba11feddc8138b6bdae0be070 372 Gene3D G3DSA:3.40.720.10 1 371 2.5E-55 T 23-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 A3L08_02040 8908b466a4cf767ceaa456cd889c4e2e 223 Gene3D G3DSA:3.40.1350.10 98 209 9.6E-43 T 23-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 A3L08_02040 8908b466a4cf767ceaa456cd889c4e2e 223 Gene3D G3DSA:2.70.180.20 1 97 3.6E-37 T 23-10-2018 A3L08_02040 8908b466a4cf767ceaa456cd889c4e2e 223 Pfam PF01939 Endonuclease NucS 2 220 1.4E-90 T 23-10-2018 IPR002793 Endonuclease NucS GO:0004519 A3L08_02040 8908b466a4cf767ceaa456cd889c4e2e 223 Hamap MF_00722 Endonuclease NucS [nucS]. 1 214 38.986 T 23-10-2018 IPR002793 Endonuclease NucS GO:0004519 A3L08_06220 cf9db2689d4b817e159191621bac4b5d 135 TIGRFAM TIGR01300 CPA3_mnhG_phaG: monovalent cation/proton antiporter, MnhG/PhaG subunit 10 110 2.1E-29 T 23-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 A3L08_06220 cf9db2689d4b817e159191621bac4b5d 135 Pfam PF03334 Na+/H+ antiporter subunit 11 95 1.4E-25 T 23-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 A3L08_02570 58b161bbe97d0ba3542b8b3947be12c3 103 SUPERFAMILY SSF81573 36 89 2.09E-6 T 23-10-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain superfamily A3L08_02570 58b161bbe97d0ba3542b8b3947be12c3 103 Gene3D G3DSA:1.20.5.620 41 91 4.4E-6 T 23-10-2018 A3L08_02570 58b161bbe97d0ba3542b8b3947be12c3 103 TIGRFAM TIGR02926 AhaH: ATP synthase archaeal, H subunit 5 88 6.7E-17 T 23-10-2018 IPR014275 ATPase, A1A0, subunit H A3L08_01305 359f20e4bf4af1bd60541e7d8e4888cc 185 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 10 176 5.4E-43 T 23-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 A3L08_01305 359f20e4bf4af1bd60541e7d8e4888cc 185 Gene3D G3DSA:3.40.920.10 1 181 1.7E-71 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 A3L08_01305 359f20e4bf4af1bd60541e7d8e4888cc 185 TIGRFAM TIGR02175 PorC_KorC: 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate family 1 180 1.4E-77 T 23-10-2018 IPR011894 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate GO:0016625|GO:0055114 A3L08_01305 359f20e4bf4af1bd60541e7d8e4888cc 185 SUPERFAMILY SSF53323 1 179 1.7E-56 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 A3L08_00525 0ed858b2f027408e1babab28b735383d 388 SUPERFAMILY SSF53901 5 229 4.76E-45 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 A3L08_00525 0ed858b2f027408e1babab28b735383d 388 Gene3D G3DSA:3.40.47.10 5 387 9.3E-122 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 A3L08_00525 0ed858b2f027408e1babab28b735383d 388 PIRSF PIRSF000429 1 385 3.5E-64 T 23-10-2018 IPR002155 Thiolase GO:0016747 A3L08_00525 0ed858b2f027408e1babab28b735383d 388 Pfam PF02803 Thiolase, C-terminal domain 260 355 5.3E-11 T 23-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 A3L08_00525 0ed858b2f027408e1babab28b735383d 388 SUPERFAMILY SSF53901 246 375 7.11E-29 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 A3L08_00525 0ed858b2f027408e1babab28b735383d 388 Pfam PF00108 Thiolase, N-terminal domain 5 221 3.7E-24 T 23-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 A3L08_02295 f384dbea2d3df234177afb513b626cc4 377 SUPERFAMILY SSF50156 204 293 3.42E-21 T 23-10-2018 IPR036034 PDZ superfamily GO:0005515 A3L08_02295 f384dbea2d3df234177afb513b626cc4 377 Pfam PF02163 Peptidase family M50 115 365 4.5E-22 T 23-10-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 A3L08_02295 f384dbea2d3df234177afb513b626cc4 377 Gene3D G3DSA:2.30.42.10 205 282 5.2E-24 T 23-10-2018 A3L08_02295 f384dbea2d3df234177afb513b626cc4 377 Pfam PF13180 PDZ domain 205 272 3.3E-14 T 23-10-2018 IPR001478 PDZ domain GO:0005515 A3L08_02295 f384dbea2d3df234177afb513b626cc4 377 SMART SM00228 190 263 2.9E-9 T 23-10-2018 IPR001478 PDZ domain GO:0005515 A3L08_02295 f384dbea2d3df234177afb513b626cc4 377 PRINTS PR01000 Sterol regulatory element binding protein site 2 protease (M50) signature 103 122 2.4E-21 T 23-10-2018 IPR001193 Membrane-bound transcription factor site-2 protease GO:0004222|GO:0006508|GO:0016020 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 A3L08_02295 f384dbea2d3df234177afb513b626cc4 377 PRINTS PR01000 Sterol regulatory element binding protein site 2 protease (M50) signature 123 137 2.4E-21 T 23-10-2018 IPR001193 Membrane-bound transcription factor site-2 protease GO:0004222|GO:0006508|GO:0016020 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 A3L08_02295 f384dbea2d3df234177afb513b626cc4 377 PRINTS PR01000 Sterol regulatory element binding protein site 2 protease (M50) signature 155 167 2.4E-21 T 23-10-2018 IPR001193 Membrane-bound transcription factor site-2 protease GO:0004222|GO:0006508|GO:0016020 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 A3L08_02295 f384dbea2d3df234177afb513b626cc4 377 PRINTS PR01000 Sterol regulatory element binding protein site 2 protease (M50) signature 139 154 2.4E-21 T 23-10-2018 IPR001193 Membrane-bound transcription factor site-2 protease GO:0004222|GO:0006508|GO:0016020 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 A3L08_01490 8d7a3666232aad9ea3b37ce4f975baac 71 SUPERFAMILY SSF46785 13 58 2.13E-5 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L08_01490 8d7a3666232aad9ea3b37ce4f975baac 71 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 9 51 1.4E-4 T 23-10-2018 IPR022687 DTXR-type HTH domain GO:0003677 A3L08_05710 2300980d310f480f9a7f18789dc1eeb2 97 Gene3D G3DSA:2.20.28.10 1 97 3.5E-33 T 23-10-2018 A3L08_05710 2300980d310f480f9a7f18789dc1eeb2 97 SUPERFAMILY SSF46785 1 95 2.09E-33 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L08_07785 f7f1d18b48845069976f5ed5c0160729 168 SUPERFAMILY SSF55154 1 164 3.43E-41 T 23-10-2018 IPR033469 CYTH-like domain superfamily Reactome: R-HSA-196819 A3L08_07785 f7f1d18b48845069976f5ed5c0160729 168 ProDom PD009560 CYCLASE ADENYLATE CYCLASE ADENYLYL CYAB LYASE CLASS CYAB-TYPE THERMOPHILIC MJ0240 2 141 1.0E-56 T 23-10-2018 A3L08_07785 f7f1d18b48845069976f5ed5c0160729 168 Pfam PF01928 CYTH domain 2 160 7.3E-27 T 23-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 A3L08_07785 f7f1d18b48845069976f5ed5c0160729 168 TIGRFAM TIGR00318 cyaB: putative adenylyl cyclase CyaB 1 164 4.1E-30 T 23-10-2018 IPR008173 Adenylyl cyclase CyaB KEGG: 00230+4.6.1.1 A3L08_07785 f7f1d18b48845069976f5ed5c0160729 168 Gene3D G3DSA:2.40.320.10 1 168 1.2E-50 T 23-10-2018 A3L08_07785 f7f1d18b48845069976f5ed5c0160729 168 SMART SM01118 1 166 2.1E-13 T 23-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 A3L08_03145 736d37cf7bdc3bc142f32a5143a8a33f 146 Pfam PF13470 PIN domain 2 109 1.1E-13 T 23-10-2018 IPR002716 PIN domain A3L08_03145 736d37cf7bdc3bc142f32a5143a8a33f 146 SUPERFAMILY SSF88723 1 115 2.43E-9 T 23-10-2018 IPR029060 PIN-like domain superfamily A3L08_03145 736d37cf7bdc3bc142f32a5143a8a33f 146 TIGRFAM TIGR00305 TIGR00305: putative toxin-antitoxin system toxin component, PIN family 2 115 9.6E-21 T 23-10-2018 IPR002850 PIN family, putative toxin-antitoxin system toxin component A3L08_03145 736d37cf7bdc3bc142f32a5143a8a33f 146 SMART SM00670 1 114 2.0E-11 T 23-10-2018 IPR002716 PIN domain A3L08_02630 6691568da1d7c2caca96ccf1ec7aba7f 276 SUPERFAMILY SSF52402 30 203 4.41E-30 T 23-10-2018 A3L08_02630 6691568da1d7c2caca96ccf1ec7aba7f 276 PIRSF PIRSF036668 1 275 7.1E-125 T 23-10-2018 IPR012121 ATPase, PP-loop, MJ1599-related A3L08_02630 6691568da1d7c2caca96ccf1ec7aba7f 276 Pfam PF06508 Queuosine biosynthesis protein QueC 54 134 1.6E-7 T 23-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 A3L08_02630 6691568da1d7c2caca96ccf1ec7aba7f 276 Gene3D G3DSA:3.40.50.620 2 163 4.9E-29 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L08_08750 27059444aa08ad93a44aa5ccfb70d7f5 476 SUPERFAMILY SSF56300 1 321 2.97E-48 T 23-10-2018 A3L08_08750 27059444aa08ad93a44aa5ccfb70d7f5 476 Gene3D G3DSA:3.30.110.80 237 337 9.7E-90 T 23-10-2018 A3L08_08750 27059444aa08ad93a44aa5ccfb70d7f5 476 Pfam PF00149 Calcineurin-like phosphoesterase 1 212 3.9E-15 T 23-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 A3L08_08750 27059444aa08ad93a44aa5ccfb70d7f5 476 Gene3D G3DSA:3.60.21.10 1 283 9.7E-90 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like A3L08_08750 27059444aa08ad93a44aa5ccfb70d7f5 476 Hamap MF_02044 DNA double-strand break repair protein Mre11 [mre11]. 1 428 22.221 T 23-10-2018 IPR032885 DNA double-strand break repair protein Mre11, archaea-type GO:0006302 A3L08_01950 6a8c05f1bd3e8e6c15bfeddff1e35376 172 Gene3D G3DSA:3.30.930.10 1 170 8.3E-64 T 23-10-2018 A3L08_01950 6a8c05f1bd3e8e6c15bfeddff1e35376 172 SUPERFAMILY SSF142913 3 170 2.07E-52 T 23-10-2018 A3L08_01950 6a8c05f1bd3e8e6c15bfeddff1e35376 172 Pfam PF11447 Protein of unknown function (DUF3201) 8 159 6.8E-68 T 23-10-2018 IPR024505 Protein of unknown function DUF3201 A3L08_09630 a14592c81e603919f42296006f1e45e0 257 Pfam PF02517 CAAX protease self-immunity 104 200 2.6E-13 T 23-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 A3L08_00650 9bb390e51d012fedd200fe276d026a4c 181 Hamap MF_00299 Probable RNA 2'-phosphotransferase [kptA]. 5 177 32.898 T 23-10-2018 IPR022928 RNA 2'-phosphotransferase KptA, putative GO:0016773 A3L08_00650 9bb390e51d012fedd200fe276d026a4c 181 Gene3D G3DSA:1.10.10.970 5 76 5.4E-22 T 23-10-2018 A3L08_00650 9bb390e51d012fedd200fe276d026a4c 181 Gene3D G3DSA:3.20.170.30 96 181 1.2E-27 T 23-10-2018 A3L08_00650 9bb390e51d012fedd200fe276d026a4c 181 Pfam PF01885 RNA 2'-phosphotransferase, Tpt1 / KptA family 6 171 5.6E-32 T 23-10-2018 IPR002745 Phosphotransferase KptA/Tpt1 GO:0006388|GO:0016772 A3L08_00650 9bb390e51d012fedd200fe276d026a4c 181 SUPERFAMILY SSF56399 8 178 7.19E-56 T 23-10-2018 A3L08_07765 7773d08271606fc18f8cf790014e7154 232 SUPERFAMILY SSF53681 119 227 7.85E-27 T 23-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A3L08_07765 7773d08271606fc18f8cf790014e7154 232 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 81 89 - T 23-10-2018 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A3L08_07765 7773d08271606fc18f8cf790014e7154 232 Pfam PF01177 Asp/Glu/Hydantoin racemase 9 222 1.7E-64 T 23-10-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A3L08_07765 7773d08271606fc18f8cf790014e7154 232 SUPERFAMILY SSF53681 4 117 2.45E-37 T 23-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A3L08_07765 7773d08271606fc18f8cf790014e7154 232 Gene3D G3DSA:3.40.50.1860 6 220 1.3E-90 T 23-10-2018 A3L08_07765 7773d08271606fc18f8cf790014e7154 232 Gene3D G3DSA:3.40.50.1860 107 214 1.3E-90 T 23-10-2018 A3L08_07765 7773d08271606fc18f8cf790014e7154 232 TIGRFAM TIGR00035 asp_race: aspartate racemase 3 230 6.1E-109 T 23-10-2018 IPR004380 Aspartate racemase GO:0006520|GO:0016855 A3L08_05245 1d70e94dccc4f68279bb33410a8dff0a 150 Gene3D G3DSA:3.40.50.2300 3 136 1.1E-44 T 23-10-2018 A3L08_05245 1d70e94dccc4f68279bb33410a8dff0a 150 SMART SM00226 4 130 1.4E-43 T 23-10-2018 IPR023485 Phosphotyrosine protein phosphatase I A3L08_05245 1d70e94dccc4f68279bb33410a8dff0a 150 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 6 127 2.8E-25 T 23-10-2018 IPR023485 Phosphotyrosine protein phosphatase I A3L08_05245 1d70e94dccc4f68279bb33410a8dff0a 150 SUPERFAMILY SSF52788 5 128 3.53E-36 T 23-10-2018 IPR036196 Phosphotyrosine protein phosphatase I superfamily A3L08_01960 bb9b39b0e9d3bd828a5c0708ad8c9719 350 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 11 321 1.6E-60 T 23-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD A3L08_01960 bb9b39b0e9d3bd828a5c0708ad8c9719 350 TIGRFAM TIGR00374 TIGR00374: TIGR00374 family protein 11 336 4.3E-61 T 23-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD A3L08_00540 2dd3bc33f2f84f53542f71044857227b 226 Hamap MF_00351 Fibrillarin-like rRNA/tRNA 2'-O-methyltransferase [flpA]. 16 226 43.78 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 A3L08_00540 2dd3bc33f2f84f53542f71044857227b 226 SUPERFAMILY SSF53335 3 225 4.02E-60 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L08_00540 2dd3bc33f2f84f53542f71044857227b 226 Gene3D G3DSA:3.40.50.150 51 226 6.6E-74 T 23-10-2018 A3L08_00540 2dd3bc33f2f84f53542f71044857227b 226 SMART SM01206 3 226 2.8E-144 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 A3L08_00540 2dd3bc33f2f84f53542f71044857227b 226 Gene3D G3DSA:3.30.200.20 1 50 3.5E-25 T 23-10-2018 A3L08_00540 2dd3bc33f2f84f53542f71044857227b 226 ProSitePatterns PS00566 Fibrillarin signature. 98 112 - T 23-10-2018 IPR020813 Fibrillarin, conserved site GO:0003723|GO:0006364|GO:0008168 A3L08_00540 2dd3bc33f2f84f53542f71044857227b 226 PIRSF PIRSF006540 1 226 1.0E-99 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 A3L08_00540 2dd3bc33f2f84f53542f71044857227b 226 PRINTS PR00052 Fibrillarin signature 73 94 2.9E-78 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 A3L08_00540 2dd3bc33f2f84f53542f71044857227b 226 PRINTS PR00052 Fibrillarin signature 123 152 2.9E-78 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 A3L08_00540 2dd3bc33f2f84f53542f71044857227b 226 PRINTS PR00052 Fibrillarin signature 204 225 2.9E-78 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 A3L08_00540 2dd3bc33f2f84f53542f71044857227b 226 PRINTS PR00052 Fibrillarin signature 153 182 2.9E-78 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 A3L08_00540 2dd3bc33f2f84f53542f71044857227b 226 PRINTS PR00052 Fibrillarin signature 98 115 2.9E-78 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 A3L08_00540 2dd3bc33f2f84f53542f71044857227b 226 PRINTS PR00052 Fibrillarin signature 23 42 2.9E-78 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 A3L08_00540 2dd3bc33f2f84f53542f71044857227b 226 PRINTS PR00052 Fibrillarin signature 46 65 2.9E-78 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 A3L08_00540 2dd3bc33f2f84f53542f71044857227b 226 Pfam PF01269 Fibrillarin 4 224 3.2E-100 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 A3L08_09815 6666cdc516a979a37ab340f0ee4f3e6e 185 Gene3D G3DSA:3.40.50.300 1 183 2.0E-37 T 23-10-2018 A3L08_09815 6666cdc516a979a37ab340f0ee4f3e6e 185 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 65 80 1.5E-5 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L08_09815 6666cdc516a979a37ab340f0ee4f3e6e 185 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 4 24 1.5E-5 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L08_09815 6666cdc516a979a37ab340f0ee4f3e6e 185 Pfam PF01926 50S ribosome-binding GTPase 3 136 3.3E-22 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L08_09815 6666cdc516a979a37ab340f0ee4f3e6e 185 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 2 176 9.4E-21 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A3L08_09815 6666cdc516a979a37ab340f0ee4f3e6e 185 SUPERFAMILY SSF52540 2 182 1.12E-35 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_04135 768e3450168b1baddfba5447313c7bba 126 Pfam PF01655 Ribosomal protein L32 18 125 1.4E-40 T 23-10-2018 IPR001515 Ribosomal protein L32e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_04135 768e3450168b1baddfba5447313c7bba 126 ProDom PD003823 RIBOSOMAL L32 RIBONUCLEOPROTEIN 60S L32E 50S L32 STRAIN CHROMOSOME DIRECT 19 126 1.0E-53 T 23-10-2018 IPR001515 Ribosomal protein L32e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_04135 768e3450168b1baddfba5447313c7bba 126 SUPERFAMILY SSF52042 5 126 1.96E-46 T 23-10-2018 IPR036351 Ribosomal protein L32e superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_04135 768e3450168b1baddfba5447313c7bba 126 ProSitePatterns PS00580 Ribosomal protein L32e signature. 21 43 - T 23-10-2018 IPR018263 Ribosomal protein L32e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_04135 768e3450168b1baddfba5447313c7bba 126 Hamap MF_00810 50S ribosomal protein L32e [rpl32e]. 2 126 32.01 T 23-10-2018 IPR023654 Ribosomal protein L32e, archaeal GO:0003735|GO:0005840|GO:0006412 A3L08_04135 768e3450168b1baddfba5447313c7bba 126 SMART SM01393 18 125 5.1E-62 T 23-10-2018 IPR001515 Ribosomal protein L32e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_01005 855ac2d73569cfde0da788e9d350506b 242 Gene3D G3DSA:3.40.50.300 5 236 2.0E-64 T 23-10-2018 A3L08_01005 855ac2d73569cfde0da788e9d350506b 242 SMART SM00382 26 201 2.8E-17 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L08_01005 855ac2d73569cfde0da788e9d350506b 242 SUPERFAMILY SSF52540 6 213 2.61E-60 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_01005 855ac2d73569cfde0da788e9d350506b 242 Pfam PF00005 ABC transporter 17 154 1.8E-30 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L08_05590 ab4160da13cc46cab5c484191eaa09ec 95 Hamap MF_00261 DNA-directed RNA polymerase subunit L [rpoL]. 1 89 19.68 T 23-10-2018 IPR022905 DNA-directed RNA polymerase subunit L (Rpo11) GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L08_05590 ab4160da13cc46cab5c484191eaa09ec 95 Pfam PF13656 RNA polymerase Rpb3/Rpb11 dimerisation domain 13 84 2.6E-20 T 23-10-2018 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 A3L08_05590 ab4160da13cc46cab5c484191eaa09ec 95 SUPERFAMILY SSF55257 1 94 4.97E-25 T 23-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L08_05590 ab4160da13cc46cab5c484191eaa09ec 95 ProSitePatterns PS01154 RNA polymerases L / 13 to 16 Kd subunits signature. 17 48 - T 23-10-2018 IPR008193 DNA-directed RNA polymerase Rpb11, 13-16kDa subunit, conserved site GO:0003677|GO:0003899|GO:0006351 A3L08_05590 ab4160da13cc46cab5c484191eaa09ec 95 Gene3D G3DSA:3.30.1360.10 1 94 6.0E-34 T 23-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L08_06940 e43d9e73174c3d00aeb6b9725d0c8ce8 272 SMART SM00382 37 233 7.0E-13 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L08_06940 e43d9e73174c3d00aeb6b9725d0c8ce8 272 Pfam PF00005 ABC transporter 29 183 2.0E-27 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L08_06940 e43d9e73174c3d00aeb6b9725d0c8ce8 272 SUPERFAMILY SSF52540 5 267 1.17E-61 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_06940 e43d9e73174c3d00aeb6b9725d0c8ce8 272 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L08_06940 e43d9e73174c3d00aeb6b9725d0c8ce8 272 Gene3D G3DSA:3.40.50.300 4 270 1.8E-72 T 23-10-2018 A3L08_06940 e43d9e73174c3d00aeb6b9725d0c8ce8 272 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 235 267 1.4E-6 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A3L08_06675 fe6c42c4659073f6778133fe4351cabd 65 Pfam PF13238 AAA domain 3 51 5.4E-9 T 23-10-2018 A3L08_06675 fe6c42c4659073f6778133fe4351cabd 65 Gene3D G3DSA:3.40.50.300 1 43 4.0E-11 T 23-10-2018 A3L08_06675 fe6c42c4659073f6778133fe4351cabd 65 SUPERFAMILY SSF52540 1 46 1.83E-10 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_07150 637ab76da96bb8c18bdf4e06e79df511 95 Hamap MF_00634 UPF0235 protein YggU [yggU]. 8 95 21.674 T 23-10-2018 IPR003746 Protein of unknown function DUF167 A3L08_07150 637ab76da96bb8c18bdf4e06e79df511 95 Pfam PF02594 Uncharacterised ACR, YggU family COG1872 12 81 4.4E-26 T 23-10-2018 IPR003746 Protein of unknown function DUF167 A3L08_07150 637ab76da96bb8c18bdf4e06e79df511 95 SMART SM01152 8 83 3.7E-37 T 23-10-2018 IPR003746 Protein of unknown function DUF167 A3L08_07150 637ab76da96bb8c18bdf4e06e79df511 95 TIGRFAM TIGR00251 TIGR00251: TIGR00251 family protein 5 86 1.6E-30 T 23-10-2018 IPR005228 Conserved hypothetical protein CHP00251 A3L08_07150 637ab76da96bb8c18bdf4e06e79df511 95 SUPERFAMILY SSF69786 3 93 7.85E-30 T 23-10-2018 IPR036591 YggU-like superfamily A3L08_07150 637ab76da96bb8c18bdf4e06e79df511 95 Gene3D G3DSA:3.30.1200.10 1 95 2.2E-34 T 23-10-2018 IPR036591 YggU-like superfamily A3L08_08045 d02f3f7dbd67eff041fde4693b29b4af 473 SUPERFAMILY SSF116734 46 237 1.41E-25 T 23-10-2018 A3L08_08045 d02f3f7dbd67eff041fde4693b29b4af 473 Pfam PF01420 Type I restriction modification DNA specificity domain 69 228 2.2E-10 T 23-10-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 A3L08_08045 d02f3f7dbd67eff041fde4693b29b4af 473 SUPERFAMILY SSF116734 285 454 4.91E-13 T 23-10-2018 A3L08_08045 d02f3f7dbd67eff041fde4693b29b4af 473 Gene3D G3DSA:3.90.220.20 280 465 1.0E-23 T 23-10-2018 A3L08_08045 d02f3f7dbd67eff041fde4693b29b4af 473 Gene3D G3DSA:3.90.220.20 38 238 1.2E-24 T 23-10-2018 A3L08_05265 a958e13936239a5ab4d6d3dc16d99b23 334 Gene3D G3DSA:1.50.10.150 3 333 8.8E-38 T 23-10-2018 IPR038665 Voltage-dependent anion channel superfamily A3L08_05265 a958e13936239a5ab4d6d3dc16d99b23 334 Pfam PF03595 Voltage-dependent anion channel 8 328 2.1E-67 T 23-10-2018 IPR004695 Voltage-dependent anion channel GO:0016021|GO:0055085 A3L08_05265 a958e13936239a5ab4d6d3dc16d99b23 334 TIGRFAM TIGR00816 tdt: C4-dicarboxylate transporter/malic acid transport protein 8 330 5.9E-89 T 23-10-2018 IPR011552 Tellurite resistance protein TehA/malic acid transport protein GO:0016021 A3L08_00180 ab7d19e9d42ffcb82c0c5d250a7471a9 63 SUPERFAMILY SSF47598 3 46 1.61E-12 T 23-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 A3L08_00180 ab7d19e9d42ffcb82c0c5d250a7471a9 63 Pfam PF01402 Ribbon-helix-helix protein, copG family 7 45 3.9E-9 T 23-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 A3L08_00180 ab7d19e9d42ffcb82c0c5d250a7471a9 63 Gene3D G3DSA:1.10.1220.10 11 46 2.2E-10 T 23-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 A3L08_04405 dbbea90af511fae80afe65ad53034cc6 99 Gene3D G3DSA:1.10.1200.200 1 99 3.2E-36 T 23-10-2018 A3L08_04405 dbbea90af511fae80afe65ad53034cc6 99 Pfam PF11537 Protein of unknown function (DUF3227) 3 94 1.2E-32 T 23-10-2018 IPR021609 Protein of unknown function DUF3227 A3L08_05335 474c83ae4596a5dce1632872680b8ee3 195 Gene3D G3DSA:3.90.550.10 3 193 1.2E-42 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L08_05335 474c83ae4596a5dce1632872680b8ee3 195 SUPERFAMILY SSF53448 1 184 5.18E-31 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L08_05335 474c83ae4596a5dce1632872680b8ee3 195 Hamap MF_00316 Molybdenum cofactor guanylyltransferase [mobA]. 1 187 19.298 T 23-10-2018 IPR013482 Molybdenum cofactor guanylyltransferase GO:0003824|GO:0006777 KEGG: 00790+2.7.7.77|MetaCyc: PWY-5964|MetaCyc: PWY-7639 A3L08_05335 474c83ae4596a5dce1632872680b8ee3 195 Pfam PF12804 MobA-like NTP transferase domain 3 141 4.5E-27 T 23-10-2018 IPR025877 MobA-like NTP transferase A3L08_07230 d2943d43ac21d0534dfefeb099f77ca2 266 SUPERFAMILY SSF52402 22 206 5.07E-33 T 23-10-2018 A3L08_07230 d2943d43ac21d0534dfefeb099f77ca2 266 Gene3D G3DSA:3.40.50.620 21 228 1.5E-28 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L08_07230 d2943d43ac21d0534dfefeb099f77ca2 266 PIRSF PIRSF036670 3 264 1.9E-120 T 23-10-2018 IPR012122 ATPase, PP-loop, MJ1016-related A3L08_07230 d2943d43ac21d0534dfefeb099f77ca2 266 Pfam PF06508 Queuosine biosynthesis protein QueC 24 84 5.2E-8 T 23-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 A3L08_09310 6fe17aa2fddd4e347b25b277cf8aecf2 242 Pfam PF13549 ATP-grasp domain 12 234 6.1E-82 T 23-10-2018 A3L08_09310 6fe17aa2fddd4e347b25b277cf8aecf2 242 SUPERFAMILY SSF56059 19 236 7.42E-46 T 23-10-2018 A3L08_09310 6fe17aa2fddd4e347b25b277cf8aecf2 242 Gene3D G3DSA:3.30.1490.20 38 115 2.2E-92 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 A3L08_09310 6fe17aa2fddd4e347b25b277cf8aecf2 242 Gene3D G3DSA:3.30.470.20 17 232 2.2E-92 T 23-10-2018 A3L08_06500 d493939fec19542ca207d562c78a4c10 623 Gene3D G3DSA:2.40.40.20 526 620 7.6E-11 T 23-10-2018 A3L08_06500 d493939fec19542ca207d562c78a4c10 623 Pfam PF00384 Molybdopterin oxidoreductase 59 458 8.7E-50 T 23-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L08_06500 d493939fec19542ca207d562c78a4c10 623 Gene3D G3DSA:3.40.50.740 68 480 3.6E-85 T 23-10-2018 A3L08_06500 d493939fec19542ca207d562c78a4c10 623 SUPERFAMILY SSF53706 5 490 3.14E-111 T 23-10-2018 A3L08_06500 d493939fec19542ca207d562c78a4c10 623 Pfam PF01568 Molydopterin dinucleotide binding domain 537 595 4.0E-9 T 23-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 A3L08_06500 d493939fec19542ca207d562c78a4c10 623 Gene3D G3DSA:3.40.228.10 136 321 3.6E-85 T 23-10-2018 A3L08_06500 d493939fec19542ca207d562c78a4c10 623 SUPERFAMILY SSF50692 542 593 2.94E-10 T 23-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily A3L08_08145 78fb82c247753e6ee2c62e27554aece3 444 Gene3D G3DSA:1.20.1250.20 4 419 1.2E-63 T 23-10-2018 A3L08_08145 78fb82c247753e6ee2c62e27554aece3 444 SUPERFAMILY SSF103473 4 421 1.15E-68 T 23-10-2018 IPR036259 MFS transporter superfamily A3L08_08145 78fb82c247753e6ee2c62e27554aece3 444 Pfam PF07690 Major Facilitator Superfamily 14 364 1.9E-53 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A3L08_00340 41706a53cd18d3bc0217c8833d208b35 109 Gene3D G3DSA:1.10.10.10 1 106 5.0E-32 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L08_00340 41706a53cd18d3bc0217c8833d208b35 109 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 12 81 3.1E-9 T 23-10-2018 IPR002831 Transcription regulator TrmB, N-terminal A3L08_00340 41706a53cd18d3bc0217c8833d208b35 109 SUPERFAMILY SSF46785 4 100 7.37E-15 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L08_01405 1de0795980e312a19fbe0170fd7692bb 278 Gene3D G3DSA:3.40.50.620 1 145 4.1E-33 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L08_01405 1de0795980e312a19fbe0170fd7692bb 278 Gene3D G3DSA:3.40.50.620 148 278 2.6E-24 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L08_01405 1de0795980e312a19fbe0170fd7692bb 278 SUPERFAMILY SSF52402 1 133 5.27E-28 T 23-10-2018 A3L08_01405 1de0795980e312a19fbe0170fd7692bb 278 PRINTS PR01438 Universal stress protein signature 254 276 4.5E-17 T 23-10-2018 IPR006015 Universal stress protein A A3L08_01405 1de0795980e312a19fbe0170fd7692bb 278 PRINTS PR01438 Universal stress protein signature 236 248 4.5E-17 T 23-10-2018 IPR006015 Universal stress protein A A3L08_01405 1de0795980e312a19fbe0170fd7692bb 278 PRINTS PR01438 Universal stress protein signature 2 20 4.5E-17 T 23-10-2018 IPR006015 Universal stress protein A A3L08_01405 1de0795980e312a19fbe0170fd7692bb 278 SUPERFAMILY SSF52402 151 276 1.76E-22 T 23-10-2018 A3L08_01405 1de0795980e312a19fbe0170fd7692bb 278 Pfam PF00582 Universal stress protein family 1 133 8.3E-23 T 23-10-2018 IPR006016 UspA A3L08_01405 1de0795980e312a19fbe0170fd7692bb 278 Pfam PF00582 Universal stress protein family 153 276 1.6E-16 T 23-10-2018 IPR006016 UspA A3L08_07420 a369ffff795b0946785299efa1617baf 293 Pfam PF00753 Metallo-beta-lactamase superfamily 16 192 1.4E-12 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L08_07420 a369ffff795b0946785299efa1617baf 293 SMART SM00849 15 201 3.1E-16 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L08_07420 a369ffff795b0946785299efa1617baf 293 Gene3D G3DSA:3.60.15.10 1 220 1.3E-28 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L08_07420 a369ffff795b0946785299efa1617baf 293 SUPERFAMILY SSF56281 4 278 1.27E-35 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L08_08895 570b8cb86102233968ce8d8a41ce33d9 68 Pfam PF00005 ABC transporter 19 66 2.2E-12 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L08_08895 570b8cb86102233968ce8d8a41ce33d9 68 Gene3D G3DSA:3.40.50.300 1 68 1.9E-20 T 23-10-2018 A3L08_08895 570b8cb86102233968ce8d8a41ce33d9 68 SUPERFAMILY SSF52540 3 65 4.57E-22 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_04350 c44bc686a7a5f9d06facfe051b4f82bc 267 ProSitePatterns PS01240 Purine and other phosphorylases family 2 signature. 48 88 - T 23-10-2018 IPR018099 Purine phosphorylase, family 2, conserved site GO:0016763 A3L08_04350 c44bc686a7a5f9d06facfe051b4f82bc 267 Gene3D G3DSA:3.40.50.1580 1 266 1.3E-99 T 23-10-2018 A3L08_04350 c44bc686a7a5f9d06facfe051b4f82bc 267 Pfam PF01048 Phosphorylase superfamily 3 246 1.7E-54 T 23-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 A3L08_04350 c44bc686a7a5f9d06facfe051b4f82bc 267 SUPERFAMILY SSF53167 1 264 2.09E-95 T 23-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 A3L08_04350 c44bc686a7a5f9d06facfe051b4f82bc 267 TIGRFAM TIGR01694 MTAP: methylthioadenosine phosphorylase 4 247 1.9E-96 T 23-10-2018 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112|Reactome: R-HSA-8950505 A3L08_04350 c44bc686a7a5f9d06facfe051b4f82bc 267 Hamap MF_01963 S-methyl-5'-thioadenosine phosphorylase [mtnP]. 2 266 43.539 T 23-10-2018 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112|Reactome: R-HSA-8950505 A3L08_06785 006077ee9015322f1345cfaf2a324856 90 Gene3D G3DSA:3.30.70.20 2 90 8.6E-17 T 23-10-2018 A3L08_06785 006077ee9015322f1345cfaf2a324856 90 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 71 82 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L08_06785 006077ee9015322f1345cfaf2a324856 90 SUPERFAMILY SSF54862 21 89 2.51E-15 T 23-10-2018 A3L08_06785 006077ee9015322f1345cfaf2a324856 90 Pfam PF12838 4Fe-4S dicluster domain 34 82 3.2E-11 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L08_06785 006077ee9015322f1345cfaf2a324856 90 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 34 45 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L08_08715 743fe172c66300f949432900b562d197 239 SUPERFAMILY SSF56281 15 236 1.07E-45 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L08_08715 743fe172c66300f949432900b562d197 239 Pfam PF00753 Metallo-beta-lactamase superfamily 31 221 4.8E-24 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L08_08715 743fe172c66300f949432900b562d197 239 Gene3D G3DSA:3.60.15.10 4 235 1.1E-46 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L08_08715 743fe172c66300f949432900b562d197 239 SMART SM00849 31 221 3.9E-41 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L08_07000 306c4da78664481f83289278a4dcfb16 1061 SUPERFAMILY SSF48208 405 994 4.42E-14 T 23-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 A3L08_02880 e143a8fd9802d29097978322ba6c5baf 193 Hamap MF_00648 Non-canonical purine NTP phosphatase. 1 175 35.377 T 23-10-2018 IPR002786 Non-canonical purine NTP phosphatase A3L08_02880 e143a8fd9802d29097978322ba6c5baf 193 Pfam PF01931 Protein of unknown function DUF84 6 169 2.1E-55 T 23-10-2018 IPR026533 Non-canonical purine NTP phosphatase/PRRC1 A3L08_02880 e143a8fd9802d29097978322ba6c5baf 193 Gene3D G3DSA:3.90.950.10 1 176 2.6E-57 T 23-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like A3L08_02880 e143a8fd9802d29097978322ba6c5baf 193 TIGRFAM TIGR00258 TIGR00258: inosine/xanthosine triphosphatase 5 175 3.9E-60 T 23-10-2018 IPR002786 Non-canonical purine NTP phosphatase A3L08_02880 e143a8fd9802d29097978322ba6c5baf 193 SUPERFAMILY SSF52972 2 175 6.54E-53 T 23-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like A3L08_06600 baa9bd2a02aaf6fe6b781faa98acfd3d 392 Gene3D G3DSA:1.10.645.10 2 386 1.4E-89 T 23-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L08_06600 baa9bd2a02aaf6fe6b781faa98acfd3d 392 Pfam PF00374 Nickel-dependent hydrogenase 39 108 5.1E-14 T 23-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 A3L08_06600 baa9bd2a02aaf6fe6b781faa98acfd3d 392 ProSitePatterns PS00507 Nickel-dependent hydrogenases large subunit signature 1. 39 64 - T 23-10-2018 IPR018194 Nickel-dependent hydrogenase, large subunit, nickel binding site GO:0008901|GO:0016151|GO:0055114 A3L08_06600 baa9bd2a02aaf6fe6b781faa98acfd3d 392 SUPERFAMILY SSF56762 3 386 3.27E-76 T 23-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L08_06485 43341c9bf871b263d6f5e86bfa9c6aac 265 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 17 152 5.3E-26 T 23-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L08_06485 43341c9bf871b263d6f5e86bfa9c6aac 265 SUPERFAMILY SSF56770 6 212 8.5E-47 T 23-10-2018 A3L08_06485 43341c9bf871b263d6f5e86bfa9c6aac 265 Gene3D G3DSA:3.40.50.700 5 165 2.1E-42 T 23-10-2018 IPR037024 [NiFe]-hydrogenase, small subunit, N-terminal domain superfamily A3L08_05720 06a256a73d61cf4f9566d70731447764 98 Hamap MF_00369 50S ribosomal protein L21e [rpl21e]. 3 97 30.066 T 23-10-2018 IPR022856 Ribosomal protein L21e, archaeal A3L08_05720 06a256a73d61cf4f9566d70731447764 98 SUPERFAMILY SSF50104 6 96 3.31E-31 T 23-10-2018 IPR008991 Translation protein SH3-like domain superfamily A3L08_05720 06a256a73d61cf4f9566d70731447764 98 ProSitePatterns PS01171 Ribosomal protein L21e signature. 38 63 - T 23-10-2018 IPR018259 Ribosomal protein L21e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_05720 06a256a73d61cf4f9566d70731447764 98 Gene3D G3DSA:2.30.30.70 2 97 2.3E-36 T 23-10-2018 IPR036948 Ribosomal protein L21 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_05720 06a256a73d61cf4f9566d70731447764 98 Pfam PF01157 Ribosomal protein L21e 6 95 7.5E-32 T 23-10-2018 IPR001147 Ribosomal protein L21e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_06845 0988f898181d7ba8a37235e6c6f504dd 328 PRINTS PR00690 Adhesin family signature 71 88 3.5E-5 T 23-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 A3L08_06845 0988f898181d7ba8a37235e6c6f504dd 328 PRINTS PR00690 Adhesin family signature 58 71 3.5E-5 T 23-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 A3L08_06845 0988f898181d7ba8a37235e6c6f504dd 328 PRINTS PR00690 Adhesin family signature 27 45 3.5E-5 T 23-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 A3L08_06845 0988f898181d7ba8a37235e6c6f504dd 328 Pfam PF01297 Zinc-uptake complex component A periplasmic 30 259 2.6E-31 T 23-10-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 A3L08_06845 0988f898181d7ba8a37235e6c6f504dd 328 Gene3D G3DSA:3.40.50.1980 27 188 2.5E-31 T 23-10-2018 A3L08_06845 0988f898181d7ba8a37235e6c6f504dd 328 SUPERFAMILY SSF53807 26 290 2.35E-43 T 23-10-2018 A3L08_05050 9231fee177c7d04648e2c6cfb5cef000 101 Pfam PF01248 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family 7 95 2.6E-19 T 23-10-2018 IPR004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45 A3L08_05050 9231fee177c7d04648e2c6cfb5cef000 101 SUPERFAMILY SSF55315 3 96 3.68E-27 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like A3L08_05050 9231fee177c7d04648e2c6cfb5cef000 101 ProSitePatterns PS00993 Ribosomal protein L30e signature 2. 70 90 - T 23-10-2018 IPR022991 Ribosomal protein L30e, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_05050 9231fee177c7d04648e2c6cfb5cef000 101 Gene3D G3DSA:3.30.1330.30 1 101 1.6E-38 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like A3L08_05050 9231fee177c7d04648e2c6cfb5cef000 101 ProSitePatterns PS00709 Ribosomal protein L30e signature 1. 14 38 - T 23-10-2018 IPR022991 Ribosomal protein L30e, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_05050 9231fee177c7d04648e2c6cfb5cef000 101 Hamap MF_00481 50S ribosomal protein L30e [rpl30e]. 2 99 29.722 T 23-10-2018 IPR000231 Ribosomal protein L30e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_01655 80302c35b4f9a7b5ba73d0e0d3c8beae 311 SUPERFAMILY SSF51556 1 310 7.03E-74 T 23-10-2018 IPR032466 Metal-dependent hydrolase A3L08_01655 80302c35b4f9a7b5ba73d0e0d3c8beae 311 ProSitePatterns PS00869 Renal dipeptidase active site. 99 121 - T 23-10-2018 IPR000180 Membrane dipeptidase, active site GO:0006508|GO:0008235|GO:0008239|GO:0016805 MetaCyc: PWY-7533|Reactome: R-HSA-2142691|Reactome: R-HSA-5423646 A3L08_01655 80302c35b4f9a7b5ba73d0e0d3c8beae 311 Pfam PF01244 Membrane dipeptidase (Peptidase family M19) 2 307 1.6E-90 T 23-10-2018 IPR008257 Peptidase M19 GO:0006508|GO:0016805 MetaCyc: PWY-7533|Reactome: R-HSA-2142691|Reactome: R-HSA-5423646 A3L08_01655 80302c35b4f9a7b5ba73d0e0d3c8beae 311 Gene3D G3DSA:3.20.20.140 1 311 2.1E-92 T 23-10-2018 A3L08_06125 98567e4ee735e257578ae5896db0d98b 180 Gene3D G3DSA:3.40.30.10 44 152 8.6E-7 T 23-10-2018 A3L08_06125 98567e4ee735e257578ae5896db0d98b 180 SUPERFAMILY SSF52833 50 129 1.37E-9 T 23-10-2018 IPR036249 Thioredoxin-like superfamily A3L08_00080 d6d0a6732b65694fabed267473571ee4 444 Pfam PF02788 Ribulose bisphosphate carboxylase large chain, N-terminal domain 12 132 2.1E-46 T 23-10-2018 IPR017443 Ribulose bisphosphate carboxylase, large subunit, ferrodoxin-like N-terminal GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 A3L08_00080 d6d0a6732b65694fabed267473571ee4 444 Gene3D G3DSA:3.30.70.150 1 136 2.2E-46 T 23-10-2018 IPR036422 RuBisCO large subunit, N-terminal domain superfamily GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 A3L08_00080 d6d0a6732b65694fabed267473571ee4 444 Gene3D G3DSA:3.20.20.110 137 438 1.3E-122 T 23-10-2018 IPR036376 Ribulose bisphosphate carboxylase, large subunit, C-terminal domain superfamily GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 A3L08_00080 d6d0a6732b65694fabed267473571ee4 444 SUPERFAMILY SSF54966 3 136 6.15E-40 T 23-10-2018 IPR036422 RuBisCO large subunit, N-terminal domain superfamily GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 A3L08_00080 d6d0a6732b65694fabed267473571ee4 444 SUPERFAMILY SSF51649 136 441 9.95E-107 T 23-10-2018 IPR036376 Ribulose bisphosphate carboxylase, large subunit, C-terminal domain superfamily GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 A3L08_00080 d6d0a6732b65694fabed267473571ee4 444 TIGRFAM TIGR03326 rubisco_III: ribulose bisphosphate carboxylase, type III 11 438 2.2E-211 T 23-10-2018 IPR017712 Ribulose bisphosphate carboxylase, type III GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 A3L08_00080 d6d0a6732b65694fabed267473571ee4 444 Hamap MF_01133 Ribulose bisphosphate carboxylase [rbcL]. 10 439 52.462 T 23-10-2018 IPR017712 Ribulose bisphosphate carboxylase, type III GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 A3L08_00080 d6d0a6732b65694fabed267473571ee4 444 Pfam PF00016 Ribulose bisphosphate carboxylase large chain, catalytic domain 142 438 4.7E-95 T 23-10-2018 IPR000685 Ribulose bisphosphate carboxylase, large subunit, C-terminal GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 A3L08_08590 0377f5e525d2951bffcf11bb82c95f6e 357 Pfam PF01008 Initiation factor 2 subunit family 55 341 3.6E-83 T 23-10-2018 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 A3L08_08590 0377f5e525d2951bffcf11bb82c95f6e 357 Gene3D G3DSA:3.40.50.10470 159 356 7.5E-61 T 23-10-2018 A3L08_08590 0377f5e525d2951bffcf11bb82c95f6e 357 Gene3D G3DSA:1.20.120.420 11 156 8.8E-46 T 23-10-2018 IPR027363 Methylthioribose-1-phosphate isomerase, N-terminal KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 A3L08_08590 0377f5e525d2951bffcf11bb82c95f6e 357 SUPERFAMILY SSF100950 12 351 1.88E-114 T 23-10-2018 IPR037171 NagB/RpiA transferase-like A3L08_08590 0377f5e525d2951bffcf11bb82c95f6e 357 TIGRFAM TIGR00512 salvage_mtnA: S-methyl-5-thioribose-1-phosphate isomerase 15 341 3.9E-129 T 23-10-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 A3L08_08590 0377f5e525d2951bffcf11bb82c95f6e 357 TIGRFAM TIGR00524 eIF-2B_rel: eIF-2B alpha/beta/delta-related uncharacterized proteins 42 342 1.6E-115 T 23-10-2018 IPR011559 Initiation factor 2B alpha/beta/delta GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 A3L08_08590 0377f5e525d2951bffcf11bb82c95f6e 357 Hamap MF_01678 Putative methylthioribose-1-phosphate isomerase [mtnA]. 13 353 39.974 T 23-10-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 A3L08_01900 bc424a3fe3b975eb536b9a0bd10ad14d 184 Gene3D G3DSA:3.90.950.10 1 184 2.0E-72 T 23-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like A3L08_01900 bc424a3fe3b975eb536b9a0bd10ad14d 184 Pfam PF01725 Ham1 family 3 178 3.2E-51 T 23-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 A3L08_01900 bc424a3fe3b975eb536b9a0bd10ad14d 184 Hamap MF_01405 dITP/XTP pyrophosphatase. 1 181 42.296 T 23-10-2018 IPR020922 dITP/XTP pyrophosphatase GO:0009143|GO:0017111 KEGG: 00230+3.6.1.66 A3L08_01900 bc424a3fe3b975eb536b9a0bd10ad14d 184 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 3 179 2.5E-63 T 23-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 A3L08_01900 bc424a3fe3b975eb536b9a0bd10ad14d 184 SUPERFAMILY SSF52972 1 182 3.14E-63 T 23-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like A3L08_02660 1d9c231eb4443d0b36ac8f05225f36de 351 SUPERFAMILY SSF161098 122 327 1.01E-13 T 23-10-2018 IPR035906 MetI-like superfamily A3L08_02660 1d9c231eb4443d0b36ac8f05225f36de 351 Gene3D G3DSA:1.10.3720.10 114 340 3.1E-16 T 23-10-2018 IPR035906 MetI-like superfamily A3L08_02660 1d9c231eb4443d0b36ac8f05225f36de 351 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 141 344 6.7E-36 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A3L08_00695 4c930f2ce5cd9efebf60e01bfd1d1357 301 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 235 255 - T 23-10-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 A3L08_00695 4c930f2ce5cd9efebf60e01bfd1d1357 301 Hamap MF_00224 Dihydroorotate dehydrogenase [pyrD]. 4 298 36.52 T 23-10-2018 IPR024920 Dihydroorotate dehydrogenase, class 1 GO:0004152|GO:0005737|GO:0006221 A3L08_00695 4c930f2ce5cd9efebf60e01bfd1d1357 301 PIRSF PIRSF000164 1 300 1.1E-87 T 23-10-2018 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 A3L08_00695 4c930f2ce5cd9efebf60e01bfd1d1357 301 Gene3D G3DSA:3.20.20.70 12 289 1.3E-92 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L08_00695 4c930f2ce5cd9efebf60e01bfd1d1357 301 TIGRFAM TIGR01037 pyrD_sub1_fam: dihydroorotate dehydrogenase family protein 4 298 1.5E-128 T 23-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 A3L08_00695 4c930f2ce5cd9efebf60e01bfd1d1357 301 ProSitePatterns PS00911 Dihydroorotate dehydrogenase signature 1. 40 59 - T 23-10-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 A3L08_00695 4c930f2ce5cd9efebf60e01bfd1d1357 301 Pfam PF01180 Dihydroorotate dehydrogenase 4 283 2.3E-64 T 23-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 A3L08_00695 4c930f2ce5cd9efebf60e01bfd1d1357 301 Gene3D G3DSA:2.30.26.10 55 212 1.3E-92 T 23-10-2018 IPR023359 Dihydroorotate dehydrogenase A, chain A, domain 2 A3L08_00695 4c930f2ce5cd9efebf60e01bfd1d1357 301 SUPERFAMILY SSF51395 1 299 2.4E-83 T 23-10-2018 A3L08_08735 51d930c21a0866ee6c1d6b65857034dd 100 Gene3D G3DSA:1.20.120.460 4 100 2.5E-33 T 23-10-2018 IPR038317 Pf1176-like superfamily A3L08_08735 51d930c21a0866ee6c1d6b65857034dd 100 Pfam PF11505 Protein of unknown function (DUF3216) 8 99 1.4E-36 T 23-10-2018 IPR023108 Domain of unknown function, DUF3216 A3L08_04545 a006f1d6b06f06e048067394f47f621b 443 Gene3D G3DSA:1.10.10.10 370 441 2.0E-15 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L08_04545 a006f1d6b06f06e048067394f47f621b 443 SMART SM00418 365 443 1.1E-10 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L08_04545 a006f1d6b06f06e048067394f47f621b 443 SUPERFAMILY SSF46785 372 439 6.83E-17 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L08_04545 a006f1d6b06f06e048067394f47f621b 443 Gene3D G3DSA:3.40.50.1100 95 191 5.3E-94 T 23-10-2018 A3L08_04545 a006f1d6b06f06e048067394f47f621b 443 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 61 352 4.6E-60 T 23-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme A3L08_04545 a006f1d6b06f06e048067394f47f621b 443 Gene3D G3DSA:3.40.50.1100 48 357 5.3E-94 T 23-10-2018 A3L08_04545 a006f1d6b06f06e048067394f47f621b 443 SUPERFAMILY SSF53686 4 357 1.96E-70 T 23-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme A3L08_04545 a006f1d6b06f06e048067394f47f621b 443 Pfam PF03551 Transcriptional regulator PadR-like family 376 439 2.0E-10 T 23-10-2018 IPR005149 Transcription regulator PadR, N-terminal A3L08_05075 38e0b0ab8ca8a6238373d1bced000241 111 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 2 106 6.3E-11 T 23-10-2018 IPR003477 mRNA interferase PemK-like GO:0003677 A3L08_05075 38e0b0ab8ca8a6238373d1bced000241 111 Gene3D G3DSA:2.30.30.110 14 110 7.5E-12 T 23-10-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor A3L08_05075 38e0b0ab8ca8a6238373d1bced000241 111 SUPERFAMILY SSF50118 2 109 3.49E-13 T 23-10-2018 A3L08_07350 f08ac265d27038e0b99da91e0371069d 133 SUPERFAMILY SSF46689 85 126 8.36E-8 T 23-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A3L08_07350 f08ac265d27038e0b99da91e0371069d 133 Gene3D G3DSA:1.10.10.60 85 128 9.2E-9 T 23-10-2018 A3L08_07350 f08ac265d27038e0b99da91e0371069d 133 Pfam PF02796 Helix-turn-helix domain of resolvase 85 123 4.0E-6 T 23-10-2018 IPR006120 Resolvase, HTH domain GO:0000150|GO:0003677|GO:0006310 A3L08_06165 71af6cf3424c8024b4e370f484a57ca5 196 Pfam PF06195 Protein of unknown function (DUF996) 39 171 5.9E-24 T 23-10-2018 IPR010397 Protein of unknown function DUF996 A3L08_02375 4fd5216f32cfd203a634f8a36500614d 386 TIGRFAM TIGR03812 tyr_de_CO2_Arch: tyrosine decarboxylase MnfA 8 380 5.1E-170 T 23-10-2018 IPR020931 Decarboxylase MfnA, archaea GO:0016831 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 A3L08_02375 4fd5216f32cfd203a634f8a36500614d 386 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 66 331 1.3E-35 T 23-10-2018 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 A3L08_02375 4fd5216f32cfd203a634f8a36500614d 386 SUPERFAMILY SSF53383 2 383 1.16E-106 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A3L08_02375 4fd5216f32cfd203a634f8a36500614d 386 Hamap MF_01610 Probable L-tyrosine/L-aspartate decarboxylase [mfnA]. 14 381 51.696 T 23-10-2018 IPR020931 Decarboxylase MfnA, archaea GO:0016831 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 A3L08_02375 4fd5216f32cfd203a634f8a36500614d 386 Gene3D G3DSA:3.90.1150.10 5 374 3.4E-126 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A3L08_02375 4fd5216f32cfd203a634f8a36500614d 386 ProSitePatterns PS00392 DDC / GAD / HDC / TyrDC pyridoxal-phosphate attachment site. 224 245 - T 23-10-2018 IPR021115 Pyridoxal-phosphate binding site GO:0016831 A3L08_02375 4fd5216f32cfd203a634f8a36500614d 386 Gene3D G3DSA:3.40.640.10 40 290 3.4E-126 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A3L08_03830 b3f7a43657c8902aeb0e41a3b8b9dfcf 108 SUPERFAMILY SSF101386 2 105 1.22E-32 T 23-10-2018 A3L08_03830 b3f7a43657c8902aeb0e41a3b8b9dfcf 108 Gene3D G3DSA:1.10.287.1080 1 105 6.8E-35 T 23-10-2018 A3L08_03830 b3f7a43657c8902aeb0e41a3b8b9dfcf 108 Pfam PF12643 MazG-like family 30 104 3.0E-23 T 23-10-2018 IPR025984 dCTP pyrophosphatase 1 GO:0009143|GO:0047429 KEGG: 00240+3.6.1.12|Reactome: R-HSA-499943 A3L08_03830 b3f7a43657c8902aeb0e41a3b8b9dfcf 108 PIRSF PIRSF029826 1 108 7.3E-40 T 23-10-2018 IPR025984 dCTP pyrophosphatase 1 GO:0009143|GO:0047429 KEGG: 00240+3.6.1.12|Reactome: R-HSA-499943 A3L08_02690 3bc40533fc525f94cb6c80457b9ee30e 290 Gene3D G3DSA:1.10.3730.20 198 280 4.5E-5 T 23-10-2018 A3L08_02690 3bc40533fc525f94cb6c80457b9ee30e 290 SUPERFAMILY SSF103481 181 277 1.7E-18 T 23-10-2018 A3L08_02690 3bc40533fc525f94cb6c80457b9ee30e 290 Pfam PF00892 EamA-like transporter family 146 273 3.2E-26 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A3L08_02690 3bc40533fc525f94cb6c80457b9ee30e 290 Pfam PF00892 EamA-like transporter family 3 137 3.7E-24 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A3L08_02690 3bc40533fc525f94cb6c80457b9ee30e 290 SUPERFAMILY SSF103481 38 138 8.37E-14 T 23-10-2018 A3L08_01920 0f21befcf5197bfbb3ff5cb47815df81 142 Pfam PF02391 MoaE protein 5 117 7.1E-37 T 23-10-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 A3L08_01920 0f21befcf5197bfbb3ff5cb47815df81 142 SUPERFAMILY SSF54690 3 135 1.44E-47 T 23-10-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 A3L08_01920 0f21befcf5197bfbb3ff5cb47815df81 142 Gene3D G3DSA:3.90.1170.40 1 136 2.5E-50 T 23-10-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 A3L08_04915 0b4a2cd0cb31892f970d56dec34ffac4 288 Gene3D G3DSA:3.40.50.1820 42 288 5.3E-46 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold A3L08_04915 0b4a2cd0cb31892f970d56dec34ffac4 288 Pfam PF00326 Prolyl oligopeptidase family 89 288 3.9E-13 T 23-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 A3L08_04915 0b4a2cd0cb31892f970d56dec34ffac4 288 SUPERFAMILY SSF53474 24 288 5.0E-55 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold A3L08_02585 9f8d909000013c18b7553b9b991b0607 203 Gene3D G3DSA:1.20.5.620 18 98 3.6E-25 T 23-10-2018 A3L08_02585 9f8d909000013c18b7553b9b991b0607 203 Hamap MF_00311 V-type proton ATPase subunit E [atpE]. 2 203 15.496 T 23-10-2018 IPR002842 V-type ATPase subunit E GO:0015991|GO:0033178|GO:0046961 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A3L08_02585 9f8d909000013c18b7553b9b991b0607 203 SUPERFAMILY SSF81573 23 82 1.18E-5 T 23-10-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain superfamily A3L08_02585 9f8d909000013c18b7553b9b991b0607 203 Pfam PF01991 ATP synthase (E/31 kDa) subunit 10 202 4.0E-38 T 23-10-2018 IPR002842 V-type ATPase subunit E GO:0015991|GO:0033178|GO:0046961 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A3L08_02585 9f8d909000013c18b7553b9b991b0607 203 Gene3D G3DSA:3.30.2320.30 100 203 1.3E-19 T 23-10-2018 IPR038495 V-type ATPase subunit E, C-terminal domain superfamily Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A3L08_02585 9f8d909000013c18b7553b9b991b0607 203 SUPERFAMILY SSF160527 81 203 1.44E-26 T 23-10-2018 A3L08_02950 640c31152e7878d8c2bc513d9f80ef7c 144 Gene3D G3DSA:1.20.1260.10 1 144 3.3E-12 T 23-10-2018 IPR012347 Ferritin-like A3L08_02950 640c31152e7878d8c2bc513d9f80ef7c 144 SUPERFAMILY SSF47240 4 142 1.64E-14 T 23-10-2018 IPR009078 Ferritin-like superfamily A3L08_00135 b4d54e9070c380bd0943f4659172c4d5 426 Gene3D G3DSA:1.20.120.1760 229 423 7.3E-56 T 23-10-2018 A3L08_00135 b4d54e9070c380bd0943f4659172c4d5 426 Gene3D G3DSA:3.90.550.10 4 219 1.7E-55 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L08_00135 b4d54e9070c380bd0943f4659172c4d5 426 SUPERFAMILY SSF53448 4 220 4.98E-33 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L08_00135 b4d54e9070c380bd0943f4659172c4d5 426 Pfam PF12804 MobA-like NTP transferase domain 5 104 6.9E-17 T 23-10-2018 IPR025877 MobA-like NTP transferase A3L08_00135 b4d54e9070c380bd0943f4659172c4d5 426 Pfam PF01066 CDP-alcohol phosphatidyltransferase 253 316 7.0E-10 T 23-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 A3L08_00135 b4d54e9070c380bd0943f4659172c4d5 426 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 294 316 - T 23-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 A3L08_02675 e644f8f6356389522dc4bb4083e6c03e 335 ProSitePatterns PS00211 ABC transporters family signature. 164 178 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L08_02675 e644f8f6356389522dc4bb4083e6c03e 335 Pfam PF00005 ABC transporter 37 191 2.8E-31 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L08_02675 e644f8f6356389522dc4bb4083e6c03e 335 SMART SM00382 45 249 4.4E-11 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L08_02675 e644f8f6356389522dc4bb4083e6c03e 335 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 243 311 2.1E-19 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A3L08_02675 e644f8f6356389522dc4bb4083e6c03e 335 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 241 331 2.2E-28 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A3L08_02675 e644f8f6356389522dc4bb4083e6c03e 335 SUPERFAMILY SSF52540 5 263 4.05E-70 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_02675 e644f8f6356389522dc4bb4083e6c03e 335 Gene3D G3DSA:3.40.50.300 3 335 9.1E-96 T 23-10-2018 A3L08_07320 2a89029a5afa3c19efee1066a3f21738 121 TIGRFAM TIGR00523 eIF-1A: translation initiation factor eIF-1A 18 109 8.3E-35 T 23-10-2018 IPR001253 Translation initiation factor 1A (eIF-1A) GO:0003743|GO:0006413 A3L08_07320 2a89029a5afa3c19efee1066a3f21738 121 ProDom PD005579 INITIATION FACTOR TRANSLATION 1A BIOSYNTHESIS EUKARYOTIC EIF-1A AIF-1A EIF-4C 1A 52 109 1.0E-25 T 23-10-2018 IPR001253 Translation initiation factor 1A (eIF-1A) GO:0003743|GO:0006413 A3L08_07320 2a89029a5afa3c19efee1066a3f21738 121 SUPERFAMILY SSF50249 6 113 8.28E-31 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L08_07320 2a89029a5afa3c19efee1066a3f21738 121 SMART SM00652 27 110 6.8E-43 T 23-10-2018 IPR001253 Translation initiation factor 1A (eIF-1A) GO:0003743|GO:0006413 A3L08_07320 2a89029a5afa3c19efee1066a3f21738 121 Pfam PF01176 Translation initiation factor 1A / IF-1 31 94 5.7E-20 T 23-10-2018 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 A3L08_07320 2a89029a5afa3c19efee1066a3f21738 121 Hamap MF_00216 Translation initiation factor 1A [eif1a]. 16 110 28.198 T 23-10-2018 IPR001253 Translation initiation factor 1A (eIF-1A) GO:0003743|GO:0006413 A3L08_07320 2a89029a5afa3c19efee1066a3f21738 121 Gene3D G3DSA:2.40.50.140 9 121 5.5E-41 T 23-10-2018 A3L08_07320 2a89029a5afa3c19efee1066a3f21738 121 ProSitePatterns PS01262 Eukaryotic initiation factor 1A signature. 40 62 - T 23-10-2018 IPR018104 Translation initiation factor 1A (eIF-1A), conserved site GO:0003743|GO:0006413 A3L08_06395 2421b061e6d7c0a7f264b654f63e5fdd 200 ProSitePatterns PS01191 Ribosomal protein S3Ae signature. 47 59 - T 23-10-2018 IPR018281 Ribosomal protein S3Ae, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_06395 2421b061e6d7c0a7f264b654f63e5fdd 200 Hamap MF_00359 30S ribosomal protein S3Ae [rps3ae]. 8 198 36.822 T 23-10-2018 IPR030838 30S ribosomal protein S3Ae GO:0003735|GO:0005840|GO:0006412 A3L08_06395 2421b061e6d7c0a7f264b654f63e5fdd 200 SMART SM01397 8 198 2.1E-101 T 23-10-2018 IPR001593 Ribosomal protein S3Ae GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_06395 2421b061e6d7c0a7f264b654f63e5fdd 200 Pfam PF01015 Ribosomal S3Ae family 11 198 9.2E-67 T 23-10-2018 IPR001593 Ribosomal protein S3Ae GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_09485 f541765ff63b1e87c01e959e23d21a98 205 SUPERFAMILY SSF52402 6 152 9.26E-24 T 23-10-2018 A3L08_09485 f541765ff63b1e87c01e959e23d21a98 205 Pfam PF00733 Asparagine synthase 8 73 3.2E-5 T 23-10-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 A3L08_09485 f541765ff63b1e87c01e959e23d21a98 205 Gene3D G3DSA:3.40.50.620 2 200 1.1E-63 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L08_06635 6e3916f2c328b031a66f87ecabe8499c 487 Pfam PF02254 TrkA-N domain 3 104 2.0E-18 T 23-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 A3L08_06635 6e3916f2c328b031a66f87ecabe8499c 487 SUPERFAMILY SSF51735 1 139 3.81E-20 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L08_06635 6e3916f2c328b031a66f87ecabe8499c 487 Pfam PF01368 DHH family 165 315 1.7E-10 T 23-10-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 A3L08_06635 6e3916f2c328b031a66f87ecabe8499c 487 Pfam PF02272 DHHA1 domain 355 473 7.3E-13 T 23-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 A3L08_06635 6e3916f2c328b031a66f87ecabe8499c 487 Gene3D G3DSA:3.90.1640.10 163 366 2.3E-28 T 23-10-2018 A3L08_06635 6e3916f2c328b031a66f87ecabe8499c 487 Gene3D G3DSA:3.40.50.720 1 141 4.4E-21 T 23-10-2018 A3L08_06635 6e3916f2c328b031a66f87ecabe8499c 487 SUPERFAMILY SSF64182 162 453 2.88E-56 T 23-10-2018 IPR038763 DHH phosphoesterase superfamily A3L08_04075 87e0ae9e29602700bb11c1d694801fcf 209 Gene3D G3DSA:3.30.300.20 1 86 1.4E-29 T 23-10-2018 IPR015946 K homology domain-like, alpha/beta A3L08_04075 87e0ae9e29602700bb11c1d694801fcf 209 SUPERFAMILY SSF54814 7 93 1.81E-25 T 23-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 A3L08_04075 87e0ae9e29602700bb11c1d694801fcf 209 Hamap MF_01309_A 30S ribosomal protein S3 [rpsC]. 2 197 42.416 T 23-10-2018 IPR027488 Ribosomal protein S3, archaeal GO:0003735|GO:0006412|GO:0015935 A3L08_04075 87e0ae9e29602700bb11c1d694801fcf 209 SMART SM00322 38 104 6.6E-7 T 23-10-2018 IPR004087 K Homology domain GO:0003676 A3L08_04075 87e0ae9e29602700bb11c1d694801fcf 209 Pfam PF07650 KH domain 17 88 3.6E-15 T 23-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_04075 87e0ae9e29602700bb11c1d694801fcf 209 Pfam PF00189 Ribosomal protein S3, C-terminal domain 99 182 1.6E-23 T 23-10-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_04075 87e0ae9e29602700bb11c1d694801fcf 209 Gene3D G3DSA:3.30.1140.32 87 209 1.4E-41 T 23-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_04075 87e0ae9e29602700bb11c1d694801fcf 209 SUPERFAMILY SSF54821 86 186 6.67E-26 T 23-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_04075 87e0ae9e29602700bb11c1d694801fcf 209 TIGRFAM TIGR01008 uS3_euk_arch: ribosomal protein uS3 3 197 1.4E-93 T 23-10-2018 IPR005703 Ribosomal protein S3, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_07400 3106478edef809a58d435d430e197ad6 621 SUPERFAMILY SSF48310 211 619 1.83E-126 T 23-10-2018 IPR036021 Aldehyde ferredoxin oxidoreductase-like, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 A3L08_07400 3106478edef809a58d435d430e197ad6 621 SUPERFAMILY SSF56228 1 209 4.71E-74 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily A3L08_07400 3106478edef809a58d435d430e197ad6 621 Gene3D G3DSA:3.60.9.10 1 209 7.3E-91 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily A3L08_07400 3106478edef809a58d435d430e197ad6 621 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 218 607 6.8E-113 T 23-10-2018 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 A3L08_07400 3106478edef809a58d435d430e197ad6 621 Gene3D G3DSA:1.10.599.10 237 607 9.0E-133 T 23-10-2018 IPR013985 Aldehyde ferredoxin oxidoreductase, domain 3 GO:0016625|GO:0051536|GO:0055114 KEGG: 00030+1.2.7.5 A3L08_07400 3106478edef809a58d435d430e197ad6 621 Gene3D G3DSA:1.10.569.10 239 419 9.0E-133 T 23-10-2018 IPR013984 Aldehyde ferredoxin oxidoreductase, domain 2 A3L08_07400 3106478edef809a58d435d430e197ad6 621 SMART SM00790 4 205 1.3E-119 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 A3L08_07400 3106478edef809a58d435d430e197ad6 621 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 6 204 6.8E-78 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 A3L08_02370 cdc40767f1ae5b38ba7dedb6b7c4f5af 286 Gene3D G3DSA:1.20.1510.10 4 200 4.8E-61 T 23-10-2018 IPR027469 Cation efflux transmembrane domain superfamily A3L08_02370 cdc40767f1ae5b38ba7dedb6b7c4f5af 286 SUPERFAMILY SSF161111 4 202 1.07E-54 T 23-10-2018 IPR027469 Cation efflux transmembrane domain superfamily A3L08_02370 cdc40767f1ae5b38ba7dedb6b7c4f5af 286 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 6 281 4.9E-81 T 23-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 A3L08_02370 cdc40767f1ae5b38ba7dedb6b7c4f5af 286 SUPERFAMILY SSF160240 205 280 1.29E-21 T 23-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 A3L08_02370 cdc40767f1ae5b38ba7dedb6b7c4f5af 286 Gene3D G3DSA:3.30.70.1350 207 282 8.2E-22 T 23-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 A3L08_02370 cdc40767f1ae5b38ba7dedb6b7c4f5af 286 Pfam PF16916 Dimerisation domain of Zinc Transporter 208 280 1.2E-22 T 23-10-2018 IPR027470 Cation efflux protein, cytoplasmic domain A3L08_02370 cdc40767f1ae5b38ba7dedb6b7c4f5af 286 Pfam PF01545 Cation efflux family 8 200 3.1E-45 T 23-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 A3L08_08410 b2360f76b798fe50bc040fd9026c1b1d 234 SUPERFAMILY SSF50037 187 232 3.34E-7 T 23-10-2018 IPR008988 Transcriptional repressor, C-terminal A3L08_08410 b2360f76b798fe50bc040fd9026c1b1d 234 Gene3D G3DSA:3.30.930.10 5 181 2.8E-55 T 23-10-2018 A3L08_08410 b2360f76b798fe50bc040fd9026c1b1d 234 Pfam PF03099 Biotin/lipoate A/B protein ligase family 13 124 9.2E-17 T 23-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 A3L08_08410 b2360f76b798fe50bc040fd9026c1b1d 234 Pfam PF02237 Biotin protein ligase C terminal domain 187 232 1.7E-5 T 23-10-2018 IPR003142 Biotin protein ligase, C-terminal GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A3L08_08410 b2360f76b798fe50bc040fd9026c1b1d 234 Gene3D G3DSA:2.30.30.100 187 233 9.7E-11 T 23-10-2018 A3L08_08410 b2360f76b798fe50bc040fd9026c1b1d 234 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 6 232 3.9E-55 T 23-10-2018 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A3L08_08410 b2360f76b798fe50bc040fd9026c1b1d 234 SUPERFAMILY SSF55681 3 171 4.47E-49 T 23-10-2018 A3L08_06175 fa4c2e3f2f680c022b4ff85c9f1c3efc 391 SUPERFAMILY SSF56762 39 391 3.27E-93 T 23-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L08_06175 fa4c2e3f2f680c022b4ff85c9f1c3efc 391 Gene3D G3DSA:1.10.645.20 27 391 2.6E-112 T 23-10-2018 IPR038290 NADH-quinone oxidoreductase, subunit D superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L08_06175 fa4c2e3f2f680c022b4ff85c9f1c3efc 391 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 139 391 2.8E-70 T 23-10-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L08_06175 fa4c2e3f2f680c022b4ff85c9f1c3efc 391 ProSitePatterns PS00535 Respiratory chain NADH dehydrogenase 49 Kd subunit signature. 61 72 - T 23-10-2018 IPR014029 NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L08_06570 4427bd099b25723d2dcdb60873f3710d 164 PIRSF PIRSF019239 1 161 8.0E-37 T 23-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 A3L08_06570 4427bd099b25723d2dcdb60873f3710d 164 Pfam PF01899 Na+/H+ ion antiporter subunit 8 158 2.7E-33 T 23-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 A3L08_05260 e18b85ae117e11481abb89dc39f1dee7 130 SUPERFAMILY SSF53146 1 112 6.67E-32 T 23-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily A3L08_05260 e18b85ae117e11481abb89dc39f1dee7 130 Gene3D G3DSA:3.30.420.130 1 104 1.8E-32 T 23-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily A3L08_05260 e18b85ae117e11481abb89dc39f1dee7 130 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 14 103 4.2E-21 T 23-10-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis A3L08_00320 6dc61a96c2eb1f4a5a3e414c5a6c665b 253 Gene3D G3DSA:3.10.330.20 1 61 6.4E-25 T 23-10-2018 A3L08_00320 6dc61a96c2eb1f4a5a3e414c5a6c665b 253 Pfam PF08704 tRNA methyltransferase complex GCD14 subunit 74 233 7.4E-27 T 23-10-2018 IPR014816 tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 GO:0016429|GO:0030488|GO:0031515 MetaCyc: PWY-6829 A3L08_00320 6dc61a96c2eb1f4a5a3e414c5a6c665b 253 Gene3D G3DSA:3.40.50.150 63 253 1.7E-67 T 23-10-2018 A3L08_00320 6dc61a96c2eb1f4a5a3e414c5a6c665b 253 PIRSF PIRSF017269 1 253 1.8E-80 T 23-10-2018 IPR014816 tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 GO:0016429|GO:0030488|GO:0031515 MetaCyc: PWY-6829 A3L08_00320 6dc61a96c2eb1f4a5a3e414c5a6c665b 253 SUPERFAMILY SSF53335 2 252 2.81E-78 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L08_00320 6dc61a96c2eb1f4a5a3e414c5a6c665b 253 Pfam PF14801 tRNA methyltransferase complex GCD14 subunit N-term 2 46 8.9E-9 T 23-10-2018 A3L08_00410 3fd4821ea2a47f98a2ab05c330bcebf5 382 Gene3D G3DSA:1.20.1530.20 2 379 2.8E-44 T 23-10-2018 IPR038770 Sodium/solute symporter superfamily A3L08_00410 3fd4821ea2a47f98a2ab05c330bcebf5 382 Pfam PF00999 Sodium/hydrogen exchanger family 8 362 1.6E-29 T 23-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 A3L08_02835 20f26d43a13da8ede001c7ed99b5700c 450 Pfam PF08323 Starch synthase catalytic domain 2 204 1.0E-36 T 23-10-2018 IPR013534 Starch synthase, catalytic domain KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 A3L08_02835 20f26d43a13da8ede001c7ed99b5700c 450 Gene3D G3DSA:3.40.50.2000 220 428 1.2E-115 T 23-10-2018 A3L08_02835 20f26d43a13da8ede001c7ed99b5700c 450 Gene3D G3DSA:3.40.50.2000 2 438 1.2E-115 T 23-10-2018 A3L08_02835 20f26d43a13da8ede001c7ed99b5700c 450 SUPERFAMILY SSF53756 1 438 6.57E-89 T 23-10-2018 A3L08_02835 20f26d43a13da8ede001c7ed99b5700c 450 Pfam PF00534 Glycosyl transferases group 1 253 420 4.8E-25 T 23-10-2018 IPR001296 Glycosyl transferase, family 1 A3L08_01850 09a58273b3edff6907dd7e41198cda95 199 Gene3D G3DSA:1.10.1760.20 32 194 5.2E-47 T 23-10-2018 A3L08_01850 09a58273b3edff6907dd7e41198cda95 199 Pfam PF07155 ECF-type riboflavin transporter, S component 38 190 3.3E-38 T 23-10-2018 IPR009825 ECF transporter, substrate-specific component-like GO:0016020 A3L08_03480 b530432f8736eab83032fd69f8ecacdc 130 SUPERFAMILY SSF88659 9 48 2.09E-7 T 23-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A3L08_03480 b530432f8736eab83032fd69f8ecacdc 130 Gene3D G3DSA:1.10.10.10 1 50 8.0E-7 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L08_03480 b530432f8736eab83032fd69f8ecacdc 130 Pfam PF08281 Sigma-70, region 4 3 46 5.7E-6 T 23-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 A3L08_07560 0217de615586d5b854067cefc10517cc 711 SUPERFAMILY SSF49452 379 453 2.35E-5 T 23-10-2018 IPR013784 Carbohydrate-binding-like fold GO:0030246 A3L08_07560 0217de615586d5b854067cefc10517cc 711 Gene3D G3DSA:2.60.40.1120 383 456 7.5E-9 T 23-10-2018 A3L08_07560 0217de615586d5b854067cefc10517cc 711 Pfam PF10633 NPCBM-associated, NEW3 domain of alpha-galactosidase 588 666 3.7E-6 T 23-10-2018 IPR018905 Alpha-galactosidase, NEW3 domain A3L08_00200 c2c5738775b89840c3dd2f73919d0fb2 401 Gene3D G3DSA:1.20.1250.20 2 192 2.1E-13 T 23-10-2018 A3L08_00200 c2c5738775b89840c3dd2f73919d0fb2 401 Pfam PF07690 Major Facilitator Superfamily 33 356 4.2E-18 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A3L08_00200 c2c5738775b89840c3dd2f73919d0fb2 401 SUPERFAMILY SSF103473 3 387 2.09E-29 T 23-10-2018 IPR036259 MFS transporter superfamily A3L08_00200 c2c5738775b89840c3dd2f73919d0fb2 401 Gene3D G3DSA:1.20.1250.20 197 391 9.8E-8 T 23-10-2018 A3L08_00945 f4487380419b8f277917737d0ae91d80 234 Gene3D G3DSA:3.40.50.300 7 219 7.9E-57 T 23-10-2018 A3L08_00945 f4487380419b8f277917737d0ae91d80 234 Hamap MF_00350 DNA repair and recombination protein RadB [radB]. 8 217 36.758 T 23-10-2018 IPR011939 DNA repair and recombination protein RadB GO:0003684|GO:0005524|GO:0006281|GO:0006310 A3L08_00945 f4487380419b8f277917737d0ae91d80 234 TIGRFAM TIGR02237 recomb_radB: DNA repair and recombination protein RadB 9 217 8.3E-71 T 23-10-2018 IPR011939 DNA repair and recombination protein RadB GO:0003684|GO:0005524|GO:0006281|GO:0006310 A3L08_00945 f4487380419b8f277917737d0ae91d80 234 PRINTS PR01874 DNA repair protein radA signature 11 39 3.1E-7 T 23-10-2018 A3L08_00945 f4487380419b8f277917737d0ae91d80 234 PRINTS PR01874 DNA repair protein radA signature 190 216 3.1E-7 T 23-10-2018 A3L08_00945 f4487380419b8f277917737d0ae91d80 234 PIRSF PIRSF003336 1 220 1.4E-96 T 23-10-2018 IPR011939 DNA repair and recombination protein RadB GO:0003684|GO:0005524|GO:0006281|GO:0006310 A3L08_00945 f4487380419b8f277917737d0ae91d80 234 SUPERFAMILY SSF52540 2 218 4.6E-36 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_00945 f4487380419b8f277917737d0ae91d80 234 Pfam PF08423 Rad51 2 205 1.1E-28 T 23-10-2018 IPR013632 DNA recombination and repair protein Rad51-like, C-terminal Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579 A3L08_03920 713253128e6c1fd59fd985454725691d 143 TIGRFAM TIGR00311 aIF-2beta: putative translation initiation factor aIF-2, beta subunit 10 143 5.0E-51 T 23-10-2018 IPR004458 Translation initiation factor 2, beta subunit GO:0003743|GO:0006413 A3L08_03920 713253128e6c1fd59fd985454725691d 143 SUPERFAMILY SSF75689 107 142 6.28E-12 T 23-10-2018 IPR016190 Translation initiation factor IF2/IF5, zinc-binding GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 A3L08_03920 713253128e6c1fd59fd985454725691d 143 Gene3D G3DSA:3.30.70.3150 41 131 5.3E-32 T 23-10-2018 A3L08_03920 713253128e6c1fd59fd985454725691d 143 Pfam PF01873 Domain found in IF2B/IF5 24 136 5.1E-37 T 23-10-2018 IPR002735 Translation initiation factor IF2/IF5 GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 A3L08_03920 713253128e6c1fd59fd985454725691d 143 SMART SM00653 30 137 4.7E-59 T 23-10-2018 IPR002735 Translation initiation factor IF2/IF5 GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 A3L08_03920 713253128e6c1fd59fd985454725691d 143 SUPERFAMILY SSF100966 9 110 6.41E-28 T 23-10-2018 IPR016189 Translation initiation factor IF2/IF5, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 A3L08_03920 713253128e6c1fd59fd985454725691d 143 Hamap MF_00232 Translation initiation factor 2 subunit beta [eif2b]. 9 143 33.188 T 23-10-2018 IPR004458 Translation initiation factor 2, beta subunit GO:0003743|GO:0006413 A3L08_04080 13067cd6c2a92a3608faa159b672de51 66 Pfam PF00831 Ribosomal L29 protein 4 61 7.5E-17 T 23-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_04080 13067cd6c2a92a3608faa159b672de51 66 ProSitePatterns PS00579 Ribosomal protein L29 signature. 40 54 - T 23-10-2018 IPR018254 Ribosomal protein L29, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_04080 13067cd6c2a92a3608faa159b672de51 66 TIGRFAM TIGR00012 L29: ribosomal protein uL29 5 61 7.5E-21 T 23-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_04080 13067cd6c2a92a3608faa159b672de51 66 Gene3D G3DSA:1.10.287.310 1 66 6.7E-20 T 23-10-2018 A3L08_04080 13067cd6c2a92a3608faa159b672de51 66 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 1 61 15.475 T 23-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_04080 13067cd6c2a92a3608faa159b672de51 66 SUPERFAMILY SSF46561 1 61 5.49E-16 T 23-10-2018 IPR036049 Ribosomal protein L29/L35 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_02990 cf7912b40a91e2264a9958c8752aef06 306 Gene3D G3DSA:1.10.8.300 193 301 2.2E-32 T 23-10-2018 A3L08_02990 cf7912b40a91e2264a9958c8752aef06 306 Gene3D G3DSA:3.40.50.300 14 180 2.1E-47 T 23-10-2018 A3L08_02990 cf7912b40a91e2264a9958c8752aef06 306 SUPERFAMILY SSF52540 3 276 1.44E-48 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_02990 cf7912b40a91e2264a9958c8752aef06 306 SMART SM00382 30 172 3.0E-4 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L08_02990 cf7912b40a91e2264a9958c8752aef06 306 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 33 163 1.2E-60 T 23-10-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 A3L08_02990 cf7912b40a91e2264a9958c8752aef06 306 PIRSF PIRSF002849 1 306 3.1E-124 T 23-10-2018 A3L08_05490 d2bc20dee9c03e6a58d0c069a4181e12 419 SUPERFAMILY SSF53448 2 312 8.55E-72 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L08_05490 d2bc20dee9c03e6a58d0c069a4181e12 419 TIGRFAM TIGR03992 Arch_glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 2 398 2.6E-154 T 23-10-2018 IPR023915 UDP-GlcNAc diphosphorylase/GlcNAc-1-P N-acetyltransferase, GlmU, archaeal-type GO:0003977|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|MetaCyc: PWY-5514 A3L08_05490 d2bc20dee9c03e6a58d0c069a4181e12 419 Pfam PF00483 Nucleotidyl transferase 2 232 1.5E-38 T 23-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 A3L08_05490 d2bc20dee9c03e6a58d0c069a4181e12 419 SUPERFAMILY SSF51161 243 409 4.07E-39 T 23-10-2018 IPR011004 Trimeric LpxA-like superfamily A3L08_05490 d2bc20dee9c03e6a58d0c069a4181e12 419 Gene3D G3DSA:3.90.550.10 1 224 2.4E-53 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L08_05490 d2bc20dee9c03e6a58d0c069a4181e12 419 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 254 287 3.9E-9 T 23-10-2018 IPR001451 Hexapeptide repeat A3L08_05490 d2bc20dee9c03e6a58d0c069a4181e12 419 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 365 398 1.9E-6 T 23-10-2018 IPR001451 Hexapeptide repeat A3L08_05490 d2bc20dee9c03e6a58d0c069a4181e12 419 Gene3D G3DSA:2.160.10.10 225 410 6.1E-60 T 23-10-2018 A3L08_06355 aea33347d039e53568d41f8e2efc5dff 133 Gene3D G3DSA:3.50.30.10 1 133 5.8E-51 T 23-10-2018 A3L08_06355 aea33347d039e53568d41f8e2efc5dff 133 Pfam PF01989 Protein of unknown function DUF126 24 103 1.1E-35 T 23-10-2018 IPR002840 Aconitase X swivel domain, putative A3L08_06355 aea33347d039e53568d41f8e2efc5dff 133 PIRSF PIRSF004966 1 131 1.2E-55 T 23-10-2018 IPR012016 Aconitase X subunit 2, putative A3L08_06355 aea33347d039e53568d41f8e2efc5dff 133 Hamap MF_00078 UPF0107 protein . 2 129 33.816 T 23-10-2018 IPR020794 Aconitase X subunit 2, archaeal, putative A3L08_06355 aea33347d039e53568d41f8e2efc5dff 133 SUPERFAMILY SSF52016 1 129 3.92E-45 T 23-10-2018 A3L08_09570 1cbf1d6dfa099166384f090bfdbd6439 154 Pfam PF01927 Mut7-C RNAse domain 1 144 1.4E-45 T 23-10-2018 IPR002782 Mut7-C RNAse domain A3L08_08270 110a90eb777cb1406307579a40b6b801 174 SUPERFAMILY SSF47240 15 163 2.03E-28 T 23-10-2018 IPR009078 Ferritin-like superfamily A3L08_08270 110a90eb777cb1406307579a40b6b801 174 Pfam PF02915 Rubrerythrin 22 157 1.4E-30 T 23-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 A3L08_08270 110a90eb777cb1406307579a40b6b801 174 Gene3D G3DSA:1.20.1260.10 12 161 7.8E-49 T 23-10-2018 IPR012347 Ferritin-like A3L08_01395 835ddf77a7a0ffb97f2c73983af00d70 104 Pfam PF03091 CutA1 divalent ion tolerance protein 5 99 4.1E-30 T 23-10-2018 IPR004323 Divalent ion tolerance protein, CutA GO:0010038 A3L08_01395 835ddf77a7a0ffb97f2c73983af00d70 104 Gene3D G3DSA:3.30.70.120 1 103 1.8E-34 T 23-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal A3L08_01395 835ddf77a7a0ffb97f2c73983af00d70 104 SUPERFAMILY SSF54913 4 100 1.0E-31 T 23-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta A3L08_06565 b4567b16ba25e3da5d3008a825cc40b9 125 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 10 120 1.4E-22 T 23-10-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like A3L08_00040 6f9a1d8b9271777cdd369b4d963eebf3 215 Pfam PF01863 Protein of unknown function DUF45 11 197 5.7E-50 T 23-10-2018 IPR002725 Protein of unknown function DUF45 A3L08_00040 6f9a1d8b9271777cdd369b4d963eebf3 215 Gene3D G3DSA:3.30.2010.10 106 201 5.4E-20 T 23-10-2018 A3L08_04675 e9594f4d7452295e9a2f68c1c94188b1 262 PIRSF PIRSF005054 1 243 1.7E-66 T 23-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 A3L08_04675 e9594f4d7452295e9a2f68c1c94188b1 262 Gene3D G3DSA:3.30.70.1890 1 122 1.0E-37 T 23-10-2018 A3L08_04675 e9594f4d7452295e9a2f68c1c94188b1 262 Gene3D G3DSA:3.30.70.1900 123 241 6.4E-37 T 23-10-2018 A3L08_04675 e9594f4d7452295e9a2f68c1c94188b1 262 Pfam PF01881 CRISPR associated protein Cas6 95 239 1.3E-33 T 23-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 A3L08_04675 e9594f4d7452295e9a2f68c1c94188b1 262 TIGRFAM TIGR01877 cas_cas6: CRISPR-associated endoribonuclease Cas6 43 238 5.1E-47 T 23-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 A3L08_04025 34bf36c950c5b42a41187e0dea56de72 388 Pfam PF07690 Major Facilitator Superfamily 12 343 1.4E-18 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A3L08_04025 34bf36c950c5b42a41187e0dea56de72 388 Gene3D G3DSA:1.20.1250.20 206 382 1.2E-7 T 23-10-2018 A3L08_04025 34bf36c950c5b42a41187e0dea56de72 388 SUPERFAMILY SSF103473 8 379 3.53E-27 T 23-10-2018 IPR036259 MFS transporter superfamily A3L08_04025 34bf36c950c5b42a41187e0dea56de72 388 Gene3D G3DSA:1.20.1250.20 1 199 2.5E-13 T 23-10-2018 A3L08_00635 51ed9c5d479c6a64ecf4c7dd973570a1 494 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 110 257 2.4E-13 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A3L08_00635 51ed9c5d479c6a64ecf4c7dd973570a1 494 Gene3D G3DSA:1.10.10.1100 399 475 5.9E-140 T 23-10-2018 A3L08_00635 51ed9c5d479c6a64ecf4c7dd973570a1 494 Gene3D G3DSA:3.50.50.60 110 482 5.9E-140 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L08_00635 51ed9c5d479c6a64ecf4c7dd973570a1 494 SUPERFAMILY SSF51905 105 276 2.07E-23 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L08_00635 51ed9c5d479c6a64ecf4c7dd973570a1 494 Gene3D G3DSA:3.10.20.440 1 95 2.2E-38 T 23-10-2018 A3L08_00635 51ed9c5d479c6a64ecf4c7dd973570a1 494 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 13 88 7.7E-16 T 23-10-2018 A3L08_00635 51ed9c5d479c6a64ecf4c7dd973570a1 494 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 331 353 3.9E-6 T 23-10-2018 A3L08_00635 51ed9c5d479c6a64ecf4c7dd973570a1 494 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 111 130 3.9E-6 T 23-10-2018 A3L08_00635 51ed9c5d479c6a64ecf4c7dd973570a1 494 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 302 318 3.9E-6 T 23-10-2018 A3L08_00635 51ed9c5d479c6a64ecf4c7dd973570a1 494 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 208 226 3.9E-6 T 23-10-2018 A3L08_00635 51ed9c5d479c6a64ecf4c7dd973570a1 494 Gene3D G3DSA:3.50.50.60 220 310 5.9E-140 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L08_02650 3a3ece83201a3f90f53be0d16c36ebd2 409 SUPERFAMILY SSF51556 53 335 6.01E-74 T 23-10-2018 IPR032466 Metal-dependent hydrolase A3L08_02650 3a3ece83201a3f90f53be0d16c36ebd2 409 SUPERFAMILY SSF51338 291 403 1.57E-23 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A3L08_02650 3a3ece83201a3f90f53be0d16c36ebd2 409 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 15 391 2.8E-119 T 23-10-2018 A3L08_02650 3a3ece83201a3f90f53be0d16c36ebd2 409 SUPERFAMILY SSF51338 16 65 3.02E-7 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A3L08_02650 3a3ece83201a3f90f53be0d16c36ebd2 409 Hamap MF_00220_A Dihydroorotase [pyrC]. 4 396 65.452 T 23-10-2018 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A3L08_02650 3a3ece83201a3f90f53be0d16c36ebd2 409 Gene3D G3DSA:3.20.20.140 44 408 1.7E-107 T 23-10-2018 A3L08_02650 3a3ece83201a3f90f53be0d16c36ebd2 409 Pfam PF01979 Amidohydrolase family 49 388 9.1E-21 T 23-10-2018 IPR006680 Amidohydrolase-related GO:0016787 A3L08_02650 3a3ece83201a3f90f53be0d16c36ebd2 409 ProSitePatterns PS00483 Dihydroorotase signature 2. 275 286 - T 23-10-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A3L08_00580 fb6e0858b24230764908e7c402b27007 93 ProDom PD029791 ORF 3'REGION GAP PF1875 PF0899 PH1831 B PHS036 2 92 8.0E-26 T 23-10-2018 IPR014418 Uncharacterised conserved protein UCP004604 A3L08_00580 fb6e0858b24230764908e7c402b27007 93 Pfam PF08967 Domain of unknown function (DUF1884) 2 92 1.6E-39 T 23-10-2018 IPR014418 Uncharacterised conserved protein UCP004604 A3L08_00580 fb6e0858b24230764908e7c402b27007 93 Gene3D G3DSA:3.30.2320.10 1 93 3.5E-27 T 23-10-2018 A3L08_00580 fb6e0858b24230764908e7c402b27007 93 SUPERFAMILY SSF111057 1 92 4.97E-32 T 23-10-2018 IPR036216 Hypothetical protein UCP004604 superfamily A3L08_00580 fb6e0858b24230764908e7c402b27007 93 PIRSF PIRSF004604 1 93 8.5E-22 T 23-10-2018 IPR014418 Uncharacterised conserved protein UCP004604 A3L08_01050 a1a874a769451271ae588e24104c6a26 448 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 241 299 3.6E-5 T 23-10-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain A3L08_01050 a1a874a769451271ae588e24104c6a26 448 SUPERFAMILY SSF52540 125 294 5.33E-12 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_01050 a1a874a769451271ae588e24104c6a26 448 Gene3D G3DSA:3.40.50.300 211 304 9.5E-8 T 23-10-2018 A3L08_01050 a1a874a769451271ae588e24104c6a26 448 Gene3D G3DSA:3.40.50.720 4 132 8.3E-9 T 23-10-2018 A3L08_04725 7a70b97f5da2b96c8776d012671073c7 434 PRINTS PR00173 Glutamate-aspartate symporter signature 214 233 2.0E-39 T 23-10-2018 A3L08_04725 7a70b97f5da2b96c8776d012671073c7 434 PRINTS PR00173 Glutamate-aspartate symporter signature 88 113 2.0E-39 T 23-10-2018 A3L08_04725 7a70b97f5da2b96c8776d012671073c7 434 PRINTS PR00173 Glutamate-aspartate symporter signature 59 79 2.0E-39 T 23-10-2018 A3L08_04725 7a70b97f5da2b96c8776d012671073c7 434 PRINTS PR00173 Glutamate-aspartate symporter signature 351 370 2.0E-39 T 23-10-2018 A3L08_04725 7a70b97f5da2b96c8776d012671073c7 434 PRINTS PR00173 Glutamate-aspartate symporter signature 316 342 2.0E-39 T 23-10-2018 A3L08_04725 7a70b97f5da2b96c8776d012671073c7 434 PRINTS PR00173 Glutamate-aspartate symporter signature 378 398 2.0E-39 T 23-10-2018 A3L08_04725 7a70b97f5da2b96c8776d012671073c7 434 PRINTS PR00173 Glutamate-aspartate symporter signature 249 268 2.0E-39 T 23-10-2018 A3L08_04725 7a70b97f5da2b96c8776d012671073c7 434 Gene3D G3DSA:1.10.3860.10 1 434 1.5E-122 T 23-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 A3L08_04725 7a70b97f5da2b96c8776d012671073c7 434 Pfam PF00375 Sodium:dicarboxylate symporter family 14 427 1.5E-107 T 23-10-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A3L08_04725 7a70b97f5da2b96c8776d012671073c7 434 SUPERFAMILY SSF118215 12 428 7.19E-101 T 23-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 A3L08_02315 ef147fb83ef6c25a0ba429a6ea781cd9 347 SUPERFAMILY SSF53756 37 345 1.3E-39 T 23-10-2018 A3L08_02315 ef147fb83ef6c25a0ba429a6ea781cd9 347 Gene3D G3DSA:3.40.50.2000 148 324 9.4E-27 T 23-10-2018 A3L08_02315 ef147fb83ef6c25a0ba429a6ea781cd9 347 Gene3D G3DSA:3.40.50.2000 21 340 9.4E-27 T 23-10-2018 A3L08_02315 ef147fb83ef6c25a0ba429a6ea781cd9 347 Pfam PF00534 Glycosyl transferases group 1 162 257 2.3E-11 T 23-10-2018 IPR001296 Glycosyl transferase, family 1 A3L08_02480 e00db42f503410ac36d2ca8da75b08f3 306 Pfam PF12679 ABC-2 family transporter protein 5 305 1.6E-47 T 23-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 A3L08_05185 30a92d65646c44d2c6c3bf0296dd9d1a 454 Hamap MF_00809 ADP-dependent glucokinase [glkA]. 2 454 59.312 T 23-10-2018 IPR031299 ADP-dependent glucokinase, archaeal KEGG: 00010+2.7.1.147|MetaCyc: PWY-6855 A3L08_05185 30a92d65646c44d2c6c3bf0296dd9d1a 454 Gene3D G3DSA:3.30.1110.20 32 204 4.6E-150 T 23-10-2018 A3L08_05185 30a92d65646c44d2c6c3bf0296dd9d1a 454 Pfam PF04587 ADP-specific Phosphofructokinase/Glucokinase conserved region 24 448 2.0E-93 T 23-10-2018 IPR007666 ADP-specific phosphofructokinase/glucokinase GO:0005975|GO:0016773 Reactome: R-HSA-70171 A3L08_05185 30a92d65646c44d2c6c3bf0296dd9d1a 454 Gene3D G3DSA:3.40.1190.20 25 448 4.6E-150 T 23-10-2018 IPR029056 Ribokinase-like A3L08_05185 30a92d65646c44d2c6c3bf0296dd9d1a 454 SUPERFAMILY SSF53613 3 453 5.35E-153 T 23-10-2018 IPR029056 Ribokinase-like A3L08_05185 30a92d65646c44d2c6c3bf0296dd9d1a 454 PIRSF PIRSF015883 9 454 4.6E-159 T 23-10-2018 IPR015990 ADP-specific phosphofructokinase/glucokinase, archaeal GO:0000287|GO:0006096|GO:0016773 A3L08_04185 ab8d29fd04c0e61acf3df6d8ee474c61 197 Gene3D G3DSA:3.40.50.300 2 177 7.5E-45 T 23-10-2018 A3L08_04185 ab8d29fd04c0e61acf3df6d8ee474c61 197 TIGRFAM TIGR02173 cyt_kin_arch: putative cytidylate kinase 6 175 1.8E-62 T 23-10-2018 IPR011892 Cytidylate kinase, putative GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 A3L08_04185 ab8d29fd04c0e61acf3df6d8ee474c61 197 Hamap MF_00239 Cytidylate kinase [cmk]. 6 178 48.083 T 23-10-2018 IPR011892 Cytidylate kinase, putative GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 A3L08_04185 ab8d29fd04c0e61acf3df6d8ee474c61 197 Pfam PF13189 Cytidylate kinase-like family 7 160 4.2E-24 T 23-10-2018 A3L08_04185 ab8d29fd04c0e61acf3df6d8ee474c61 197 SUPERFAMILY SSF52540 7 175 4.3E-22 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_01400 64e709921cfe5dbd486df7e152e6ec25 195 Gene3D G3DSA:3.30.2170.10 3 195 1.4E-61 T 23-10-2018 A3L08_01400 64e709921cfe5dbd486df7e152e6ec25 195 Hamap MF_00582 UPF0215 protein . 9 189 34.757 T 23-10-2018 IPR002802 Protein of unknown function DUF99 A3L08_01400 64e709921cfe5dbd486df7e152e6ec25 195 Pfam PF01949 Protein of unknown function DUF99 8 188 4.8E-66 T 23-10-2018 IPR002802 Protein of unknown function DUF99 A3L08_01400 64e709921cfe5dbd486df7e152e6ec25 195 PIRSF PIRSF006380 1 195 1.5E-71 T 23-10-2018 IPR002802 Protein of unknown function DUF99 A3L08_01400 64e709921cfe5dbd486df7e152e6ec25 195 ProDom PD016744 UPF0215 ST0304 TK2033 MA4269 PAE0952 SSO0256 NEQ431 MK0057 PTO0905 TV0037 72 184 1.0E-44 T 23-10-2018 IPR002802 Protein of unknown function DUF99 A3L08_06585 ebf4ae3f9ec807a479f1c7c77f4d2990 352 Gene3D G3DSA:3.50.50.60 132 283 1.1E-55 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L08_06585 ebf4ae3f9ec807a479f1c7c77f4d2990 352 Gene3D G3DSA:3.50.50.60 22 343 1.1E-55 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L08_06585 ebf4ae3f9ec807a479f1c7c77f4d2990 352 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 312 330 2.6E-16 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A3L08_06585 ebf4ae3f9ec807a479f1c7c77f4d2990 352 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 20 42 2.6E-16 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A3L08_06585 ebf4ae3f9ec807a479f1c7c77f4d2990 352 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 224 240 2.6E-16 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A3L08_06585 ebf4ae3f9ec807a479f1c7c77f4d2990 352 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 170 194 2.6E-16 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A3L08_06585 ebf4ae3f9ec807a479f1c7c77f4d2990 352 SUPERFAMILY SSF51971 17 284 1.77E-57 T 23-10-2018 A3L08_06585 ebf4ae3f9ec807a479f1c7c77f4d2990 352 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 19 336 1.0E-35 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A3L08_06585 ebf4ae3f9ec807a479f1c7c77f4d2990 352 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 302 324 9.1E-23 T 23-10-2018 A3L08_06585 ebf4ae3f9ec807a479f1c7c77f4d2990 352 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 174 192 9.1E-23 T 23-10-2018 A3L08_06585 ebf4ae3f9ec807a479f1c7c77f4d2990 352 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 21 40 9.1E-23 T 23-10-2018 A3L08_06585 ebf4ae3f9ec807a479f1c7c77f4d2990 352 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 119 137 9.1E-23 T 23-10-2018 A3L08_06585 ebf4ae3f9ec807a479f1c7c77f4d2990 352 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 275 291 9.1E-23 T 23-10-2018 A3L08_03875 e06e955cbe9bb88050fba37828d81bf3 236 Pfam PF03367 ZPR1 zinc-finger domain 21 177 6.8E-39 T 23-10-2018 IPR004457 Zinc finger, ZPR1-type GO:0008270 A3L08_03875 e06e955cbe9bb88050fba37828d81bf3 236 TIGRFAM TIGR00340 zpr1_rel: zinc finger protein ZPR1 homolog 22 187 6.9E-70 T 23-10-2018 IPR004470 Zinc finger, ZPR1-type, subgroup GO:0008270 A3L08_03875 e06e955cbe9bb88050fba37828d81bf3 236 TIGRFAM TIGR00310 ZPR1_znf: ZPR1 zinc finger domain 21 200 1.0E-60 T 23-10-2018 IPR004457 Zinc finger, ZPR1-type GO:0008270 A3L08_03875 e06e955cbe9bb88050fba37828d81bf3 236 Gene3D G3DSA:2.60.120.1040 69 194 1.3E-21 T 23-10-2018 A3L08_03875 e06e955cbe9bb88050fba37828d81bf3 236 Gene3D G3DSA:2.20.25.420 13 65 4.3E-7 T 23-10-2018 A3L08_03875 e06e955cbe9bb88050fba37828d81bf3 236 SMART SM00709 20 180 1.3E-75 T 23-10-2018 IPR004457 Zinc finger, ZPR1-type GO:0008270 A3L08_05100 70bc33bdc7292e985cf22eaae2cfc30e 67 SUPERFAMILY SSF54285 5 67 1.45E-13 T 23-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp A3L08_05100 70bc33bdc7292e985cf22eaae2cfc30e 67 Gene3D G3DSA:3.10.20.30 1 67 1.1E-25 T 23-10-2018 IPR012675 Beta-grasp domain superfamily A3L08_05100 70bc33bdc7292e985cf22eaae2cfc30e 67 Pfam PF02597 ThiS family 10 67 5.0E-12 T 23-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 A3L08_02780 e8e7850c8857f67f5180c50cd5743554 624 TIGRFAM TIGR00728 OPT_sfam: oligopeptide transporter, OPT superfamily 10 594 1.8E-120 T 23-10-2018 IPR004813 Oligopeptide transporter, OPT superfamily GO:0055085 A3L08_02780 e8e7850c8857f67f5180c50cd5743554 624 TIGRFAM TIGR00733 TIGR00733: oligopeptide transporter, OPT family 15 591 3.3E-254 T 23-10-2018 IPR004814 Oligopeptide transporter OPT A3L08_02780 e8e7850c8857f67f5180c50cd5743554 624 Pfam PF03169 OPT oligopeptide transporter protein 15 589 6.3E-104 T 23-10-2018 IPR004813 Oligopeptide transporter, OPT superfamily GO:0055085 A3L08_04490 a79ce96abdb6ddb6a35d5f960c84ec2d 138 Gene3D G3DSA:3.30.70.1150 51 138 2.3E-36 T 23-10-2018 IPR027271 Acetolactate synthase/Transcription factor NikR, C-terminal A3L08_04490 a79ce96abdb6ddb6a35d5f960c84ec2d 138 Hamap MF_00476 Nickel-responsive regulator [nikR]. 3 133 30.392 T 23-10-2018 IPR022988 Nickel-responsive transcriptional regulator NikR GO:0003677|GO:0006355|GO:0010045|GO:0016151 A3L08_04490 a79ce96abdb6ddb6a35d5f960c84ec2d 138 SUPERFAMILY SSF47598 2 48 1.41E-13 T 23-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 A3L08_04490 a79ce96abdb6ddb6a35d5f960c84ec2d 138 Pfam PF01402 Ribbon-helix-helix protein, copG family 5 42 2.4E-8 T 23-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 A3L08_04490 a79ce96abdb6ddb6a35d5f960c84ec2d 138 SUPERFAMILY SSF55021 52 133 2.52E-28 T 23-10-2018 A3L08_04490 a79ce96abdb6ddb6a35d5f960c84ec2d 138 Pfam PF08753 NikR C terminal nickel binding domain 55 131 5.9E-33 T 23-10-2018 IPR014864 Transcription factor, NikR, nickel binding C-terminal A3L08_04490 a79ce96abdb6ddb6a35d5f960c84ec2d 138 Gene3D G3DSA:1.10.1220.10 10 50 4.4E-22 T 23-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 A3L08_04900 3a997b7206e4d91608c82d0d9bbc58b1 205 Hamap MF_00165 Thymidylate kinase [tmk]. 1 202 27.99 T 23-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 A3L08_04900 3a997b7206e4d91608c82d0d9bbc58b1 205 SUPERFAMILY SSF52540 1 199 3.76E-52 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_04900 3a997b7206e4d91608c82d0d9bbc58b1 205 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 1 194 6.5E-58 T 23-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 A3L08_04900 3a997b7206e4d91608c82d0d9bbc58b1 205 Gene3D G3DSA:3.40.50.300 1 202 2.0E-67 T 23-10-2018 A3L08_04900 3a997b7206e4d91608c82d0d9bbc58b1 205 ProSitePatterns PS01331 Thymidylate kinase signature. 96 108 - T 23-10-2018 IPR018095 Thymidylate kinase, conserved site GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 A3L08_04900 3a997b7206e4d91608c82d0d9bbc58b1 205 Pfam PF02223 Thymidylate kinase 5 194 2.1E-54 T 23-10-2018 IPR039430 Thymidylate kinase-like domain KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210 A3L08_00015 fab09bf12f2d225a68455e3ace67abe4 366 Pfam PF01170 Putative RNA methylase family UPF0020 175 321 4.2E-12 T 23-10-2018 IPR000241 Putative RNA methylase domain A3L08_00015 fab09bf12f2d225a68455e3ace67abe4 366 Gene3D G3DSA:3.40.50.150 169 348 3.0E-27 T 23-10-2018 A3L08_00015 fab09bf12f2d225a68455e3ace67abe4 366 SUPERFAMILY SSF53335 172 339 1.84E-22 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L08_07585 08868bce0be7be500062e8b7edbaf57e 222 ProSitePatterns PS00109 Tyrosine protein kinases specific active-site signature. 126 138 - T 23-10-2018 IPR008266 Tyrosine-protein kinase, active site GO:0004672|GO:0006468 A3L08_07585 08868bce0be7be500062e8b7edbaf57e 222 Gene3D G3DSA:3.30.200.20 21 90 1.6E-27 T 23-10-2018 A3L08_07585 08868bce0be7be500062e8b7edbaf57e 222 SMART SM00220 1 221 6.0E-4 T 23-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A3L08_07585 08868bce0be7be500062e8b7edbaf57e 222 Pfam PF01163 RIO1 family 44 149 1.5E-16 T 23-10-2018 A3L08_07585 08868bce0be7be500062e8b7edbaf57e 222 TIGRFAM TIGR03724 arch_bud32: Kae1-associated kinase Bud32 4 215 9.2E-74 T 23-10-2018 IPR022495 Serine/threonine-protein kinase Bud32 GO:0004674 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6782315|Reactome: R-HSA-6804756 A3L08_07585 08868bce0be7be500062e8b7edbaf57e 222 Gene3D G3DSA:1.10.510.10 99 217 2.6E-33 T 23-10-2018 A3L08_07585 08868bce0be7be500062e8b7edbaf57e 222 SUPERFAMILY SSF56112 2 159 5.66E-29 T 23-10-2018 IPR011009 Protein kinase-like domain superfamily A3L08_04070 de6c1cc7285acde2594278a73f2315a8 156 Gene3D G3DSA:3.90.470.10 6 156 2.3E-51 T 23-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 A3L08_04070 de6c1cc7285acde2594278a73f2315a8 156 SUPERFAMILY SSF54843 8 153 3.14E-47 T 23-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 A3L08_04070 de6c1cc7285acde2594278a73f2315a8 156 ProSitePatterns PS00464 Ribosomal protein L22 signature. 127 151 - T 23-10-2018 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_04070 de6c1cc7285acde2594278a73f2315a8 156 TIGRFAM TIGR01038 uL22_arch_euk: ribosomal protein uL22 8 153 2.7E-66 T 23-10-2018 IPR005721 Ribosomal protein L22/L17, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_04070 de6c1cc7285acde2594278a73f2315a8 156 Hamap MF_01331_A 50S ribosomal protein L22 [rplV]. 4 154 33.643 T 23-10-2018 IPR005721 Ribosomal protein L22/L17, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_04070 de6c1cc7285acde2594278a73f2315a8 156 Pfam PF00237 Ribosomal protein L22p/L17e 21 151 3.5E-35 T 23-10-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 A3L08_05440 b6a5fd663b417b5140621e6e7d7cc93e 95 SUPERFAMILY SSF158372 5 85 1.44E-25 T 23-10-2018 IPR036809 AF1782-like superfamily A3L08_05440 b6a5fd663b417b5140621e6e7d7cc93e 95 Gene3D G3DSA:1.20.1270.90 5 84 9.2E-25 T 23-10-2018 A3L08_05440 b6a5fd663b417b5140621e6e7d7cc93e 95 Pfam PF04010 Protein of unknown function (DUF357) 12 84 3.5E-29 T 23-10-2018 IPR023140 Domain of unknown function DUF357 A3L08_05445 1a51c68bb342ff6fdbb0675be2b6a753 126 Pfam PF04475 Protein of unknown function (DUF555) 3 104 2.1E-40 T 23-10-2018 IPR007564 Uncharacterised protein family UPF0212 A3L08_05445 1a51c68bb342ff6fdbb0675be2b6a753 126 ProDom PD020367 UPF0212 RRNAC1165 RRNAC0441 AF0282 VNG1264C MJ0068 PYRAB08340 PH1312 MA1372 TK1194 1 102 4.0E-51 T 23-10-2018 IPR007564 Uncharacterised protein family UPF0212 A3L08_05445 1a51c68bb342ff6fdbb0675be2b6a753 126 PIRSF PIRSF016934 1 122 5.1E-53 T 23-10-2018 IPR007564 Uncharacterised protein family UPF0212 A3L08_05445 1a51c68bb342ff6fdbb0675be2b6a753 126 Hamap MF_01223 UPF0212 protein . 1 112 32.369 T 23-10-2018 IPR007564 Uncharacterised protein family UPF0212 A3L08_07405 123739c617089ecae3d4df33f4e91246 282 Hamap MF_01922 tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase [taw2]. 30 280 40.859 T 23-10-2018 IPR030867 tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase GO:0006400|GO:0016765 MetaCyc: PWY-7286 A3L08_07405 123739c617089ecae3d4df33f4e91246 282 SUPERFAMILY SSF53335 23 280 6.57E-70 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L08_07405 123739c617089ecae3d4df33f4e91246 282 Pfam PF02475 Met-10+ like-protein 33 227 1.9E-68 T 23-10-2018 IPR030382 SAM-dependent methyltransferase TRM5/TYW2-type Reactome: R-HSA-6782861 A3L08_07405 123739c617089ecae3d4df33f4e91246 282 Gene3D G3DSA:3.30.300.110 23 90 6.2E-28 T 23-10-2018 A3L08_07405 123739c617089ecae3d4df33f4e91246 282 Gene3D G3DSA:3.40.50.150 91 282 2.1E-58 T 23-10-2018 A3L08_02945 deebbfb9d97e90fd05cccce68fea6fd5 909 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 113 268 2.8E-28 T 23-10-2018 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A3L08_02945 deebbfb9d97e90fd05cccce68fea6fd5 909 SUPERFAMILY SSF48168 9 154 6.02E-13 T 23-10-2018 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A3L08_02945 deebbfb9d97e90fd05cccce68fea6fd5 909 Pfam PF02867 Ribonucleotide reductase, barrel domain 271 771 6.1E-234 T 23-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A3L08_02945 deebbfb9d97e90fd05cccce68fea6fd5 909 SUPERFAMILY SSF51998 270 782 1.77E-153 T 23-10-2018 A3L08_02945 deebbfb9d97e90fd05cccce68fea6fd5 909 TIGRFAM TIGR02504 NrdJ_Z: ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent 120 780 6.2E-231 T 23-10-2018 IPR013344 Ribonucleotide reductase, adenosylcobalamin-dependent GO:0000166|GO:0004748|GO:0031419|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A3L08_02945 deebbfb9d97e90fd05cccce68fea6fd5 909 PRINTS PR01183 Ribonucleotide reductase large chain signature 493 516 1.7E-31 T 23-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A3L08_02945 deebbfb9d97e90fd05cccce68fea6fd5 909 PRINTS PR01183 Ribonucleotide reductase large chain signature 531 553 1.7E-31 T 23-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A3L08_02945 deebbfb9d97e90fd05cccce68fea6fd5 909 PRINTS PR01183 Ribonucleotide reductase large chain signature 624 651 1.7E-31 T 23-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A3L08_02945 deebbfb9d97e90fd05cccce68fea6fd5 909 PRINTS PR01183 Ribonucleotide reductase large chain signature 559 582 1.7E-31 T 23-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A3L08_02945 deebbfb9d97e90fd05cccce68fea6fd5 909 PRINTS PR01183 Ribonucleotide reductase large chain signature 346 365 1.7E-31 T 23-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A3L08_02945 deebbfb9d97e90fd05cccce68fea6fd5 909 Pfam PF03477 ATP cone domain 5 92 2.5E-21 T 23-10-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 A3L08_02945 deebbfb9d97e90fd05cccce68fea6fd5 909 Gene3D G3DSA:3.20.70.20 209 786 6.4E-204 T 23-10-2018 A3L08_02945 deebbfb9d97e90fd05cccce68fea6fd5 909 Gene3D G3DSA:3.20.70.20 61 166 3.5E-6 T 23-10-2018 A3L08_01105 228451dbfc5fdabb7f3570dfaf655d97 70 SUPERFAMILY SSF141694 8 68 8.89E-14 T 23-10-2018 A3L08_01105 228451dbfc5fdabb7f3570dfaf655d97 70 Pfam PF01954 Protein of unknown function DUF104 8 64 2.2E-15 T 23-10-2018 IPR008203 Uncharacterised protein family UPF0165 A3L08_01105 228451dbfc5fdabb7f3570dfaf655d97 70 Gene3D G3DSA:4.10.1150.10 7 70 5.1E-13 T 23-10-2018 IPR024069 AF2212-like domain superfamily A3L08_02215 e3f8f2dd74d775365793df0b30c3ec1a 317 Gene3D G3DSA:3.40.50.300 21 187 1.5E-49 T 23-10-2018 A3L08_02215 e3f8f2dd74d775365793df0b30c3ec1a 317 SUPERFAMILY SSF52540 15 287 7.26E-49 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_02215 e3f8f2dd74d775365793df0b30c3ec1a 317 Gene3D G3DSA:1.10.8.300 202 311 2.7E-37 T 23-10-2018 A3L08_02215 e3f8f2dd74d775365793df0b30c3ec1a 317 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 40 170 4.9E-68 T 23-10-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 A3L08_02215 e3f8f2dd74d775365793df0b30c3ec1a 317 PIRSF PIRSF002849 1 316 2.4E-139 T 23-10-2018 A3L08_05400 70c7ff23a2ad3372e46fb8d52177fca4 1428 Gene3D G3DSA:3.40.50.200 316 642 2.0E-66 T 23-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 A3L08_05400 70c7ff23a2ad3372e46fb8d52177fca4 1428 PRINTS PR00723 Subtilisin serine protease family (S8) signature 375 388 4.6E-19 T 23-10-2018 IPR015500 Peptidase S8, subtilisin-related A3L08_05400 70c7ff23a2ad3372e46fb8d52177fca4 1428 PRINTS PR00723 Subtilisin serine protease family (S8) signature 572 588 4.6E-19 T 23-10-2018 IPR015500 Peptidase S8, subtilisin-related A3L08_05400 70c7ff23a2ad3372e46fb8d52177fca4 1428 PRINTS PR00723 Subtilisin serine protease family (S8) signature 182 201 4.6E-19 T 23-10-2018 IPR015500 Peptidase S8, subtilisin-related A3L08_05400 70c7ff23a2ad3372e46fb8d52177fca4 1428 SUPERFAMILY SSF52743 166 633 5.12E-63 T 23-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 A3L08_05400 70c7ff23a2ad3372e46fb8d52177fca4 1428 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 187 198 - T 23-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site A3L08_05400 70c7ff23a2ad3372e46fb8d52177fca4 1428 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 573 583 - T 23-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site A3L08_05400 70c7ff23a2ad3372e46fb8d52177fca4 1428 Gene3D G3DSA:3.40.50.200 164 298 2.2E-7 T 23-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 A3L08_05400 70c7ff23a2ad3372e46fb8d52177fca4 1428 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 379 389 - T 23-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site A3L08_05400 70c7ff23a2ad3372e46fb8d52177fca4 1428 Pfam PF00082 Subtilase family 182 625 2.1E-55 T 23-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A3L08_06690 0893dcd6663916f26527ffdc44e99365 543 Gene3D G3DSA:3.30.420.40 9 312 5.7E-64 T 23-10-2018 A3L08_06690 0893dcd6663916f26527ffdc44e99365 543 Gene3D G3DSA:3.90.870.20 330 534 3.7E-74 T 23-10-2018 IPR038152 Carbamoyltransferase, C-terminal domain superfamily A3L08_06690 0893dcd6663916f26527ffdc44e99365 543 Pfam PF16861 Carbamoyltransferase C-terminus 365 533 1.1E-63 T 23-10-2018 IPR031730 Carbamoyltransferase, C-terminal A3L08_06690 0893dcd6663916f26527ffdc44e99365 543 SUPERFAMILY SSF53067 9 315 1.94E-12 T 23-10-2018 A3L08_06690 0893dcd6663916f26527ffdc44e99365 543 Pfam PF02543 Carbamoyltransferase N-terminus 87 312 6.3E-38 T 23-10-2018 IPR003696 Carbamoyltransferase GO:0003824|GO:0009058 A3L08_06690 0893dcd6663916f26527ffdc44e99365 543 Pfam PF02543 Carbamoyltransferase N-terminus 2 64 3.0E-7 T 23-10-2018 IPR003696 Carbamoyltransferase GO:0003824|GO:0009058 A3L08_06690 0893dcd6663916f26527ffdc44e99365 543 Gene3D G3DSA:3.30.420.350 95 305 5.7E-64 T 23-10-2018 A3L08_00460 ee71d55e71ff397541125c1be4aa117f 458 SUPERFAMILY SSF52210 292 451 4.45E-39 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A3L08_00460 ee71d55e71ff397541125c1be4aa117f 458 Pfam PF13380 CoA binding domain 10 135 1.2E-26 T 23-10-2018 IPR003781 CoA-binding GO:0048037 A3L08_00460 ee71d55e71ff397541125c1be4aa117f 458 SUPERFAMILY SSF52210 132 288 2.49E-45 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A3L08_00460 ee71d55e71ff397541125c1be4aa117f 458 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 150 287 9.2E-57 T 23-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain A3L08_00460 ee71d55e71ff397541125c1be4aa117f 458 Gene3D G3DSA:3.40.50.261 130 289 8.3E-62 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A3L08_00460 ee71d55e71ff397541125c1be4aa117f 458 SUPERFAMILY SSF51735 3 130 4.14E-39 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L08_00460 ee71d55e71ff397541125c1be4aa117f 458 Gene3D G3DSA:3.40.50.720 3 129 1.5E-46 T 23-10-2018 A3L08_00460 ee71d55e71ff397541125c1be4aa117f 458 SMART SM00881 6 100 8.2E-35 T 23-10-2018 IPR003781 CoA-binding GO:0048037 A3L08_00460 ee71d55e71ff397541125c1be4aa117f 458 Gene3D G3DSA:3.40.50.261 290 458 2.8E-65 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A3L08_02385 11b4be88d5ba862f768f13fe100bcc64 82 Pfam PF01998 Protein of unknown function DUF131 32 74 3.4E-17 T 23-10-2018 IPR002849 Protein of unknown function DUF131 A3L08_03105 9b014e0f002f75cc11023d0e807e5b09 379 Gene3D G3DSA:3.40.50.2000 28 364 3.1E-37 T 23-10-2018 A3L08_03105 9b014e0f002f75cc11023d0e807e5b09 379 Pfam PF13692 Glycosyl transferases group 1 198 327 8.5E-16 T 23-10-2018 A3L08_03105 9b014e0f002f75cc11023d0e807e5b09 379 Gene3D G3DSA:3.40.50.2000 178 357 3.1E-37 T 23-10-2018 A3L08_03105 9b014e0f002f75cc11023d0e807e5b09 379 SUPERFAMILY SSF53756 21 369 5.23E-37 T 23-10-2018 A3L08_09660 cb556d53d7e7109f9d52a8387a32abc9 393 SUPERFAMILY SSF103473 23 385 2.49E-31 T 23-10-2018 IPR036259 MFS transporter superfamily A3L08_09660 cb556d53d7e7109f9d52a8387a32abc9 393 Gene3D G3DSA:1.20.1250.20 18 382 2.5E-28 T 23-10-2018 A3L08_05995 5695abb680cd38ec2a931cb2cfa60f7a 327 Pfam PF02272 DHHA1 domain 241 317 2.8E-12 T 23-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 A3L08_05995 5695abb680cd38ec2a931cb2cfa60f7a 327 SUPERFAMILY SSF64182 18 306 5.23E-50 T 23-10-2018 IPR038763 DHH phosphoesterase superfamily A3L08_05995 5695abb680cd38ec2a931cb2cfa60f7a 327 Pfam PF01368 DHH family 19 159 4.8E-12 T 23-10-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 A3L08_05995 5695abb680cd38ec2a931cb2cfa60f7a 327 Gene3D G3DSA:3.10.310.40 220 321 9.2E-7 T 23-10-2018 A3L08_05995 5695abb680cd38ec2a931cb2cfa60f7a 327 Gene3D G3DSA:3.90.1640.10 7 188 1.3E-37 T 23-10-2018 A3L08_02965 21ccb6202b64b48a26d68edc9c9384b1 317 SUPERFAMILY SSF51735 1 314 1.21E-84 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L08_02965 21ccb6202b64b48a26d68edc9c9384b1 317 Gene3D G3DSA:3.90.25.10 223 317 3.4E-28 T 23-10-2018 A3L08_02965 21ccb6202b64b48a26d68edc9c9384b1 317 Gene3D G3DSA:3.90.25.10 180 222 2.2E-12 T 23-10-2018 A3L08_02965 21ccb6202b64b48a26d68edc9c9384b1 317 Gene3D G3DSA:3.40.50.720 1 179 9.0E-51 T 23-10-2018 A3L08_02965 21ccb6202b64b48a26d68edc9c9384b1 317 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 240 4.5E-55 T 23-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 A3L08_09655 533dc203bf68dbc40ea3d537912a0f2b 278 SUPERFAMILY SSF55729 1 134 4.9E-23 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase A3L08_09655 533dc203bf68dbc40ea3d537912a0f2b 278 Gene3D G3DSA:3.40.630.30 1 183 2.2E-31 T 23-10-2018 A3L08_09655 533dc203bf68dbc40ea3d537912a0f2b 278 Pfam PF00583 Acetyltransferase (GNAT) family 28 126 3.4E-13 T 23-10-2018 IPR000182 GNAT domain A3L08_05030 5263d567cc2b311fab56856f0e49ebac 82 Pfam PF01191 RNA polymerase Rpb5, C-terminal domain 7 79 6.0E-32 T 23-10-2018 IPR000783 RNA polymerase, subunit H/Rpb5 C-terminal GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A3L08_05030 5263d567cc2b311fab56856f0e49ebac 82 ProDom PD005155 RNA POLYMERASE DNA-DIRECTED SUBUNIT NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION II H POLYPEPTIDE 37 79 2.0E-17 T 23-10-2018 IPR000783 RNA polymerase, subunit H/Rpb5 C-terminal GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A3L08_05030 5263d567cc2b311fab56856f0e49ebac 82 ProSitePatterns PS01110 RNA polymerases H / 23 Kd subunits signature. 12 25 - T 23-10-2018 IPR020608 RNA polymerase, subunit H/Rpb5, conserved site Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A3L08_05030 5263d567cc2b311fab56856f0e49ebac 82 Hamap MF_00025 DNA-directed RNA polymerase subunit H [rpoH]. 7 80 23.72 T 23-10-2018 IPR020609 Archaeal RpoH /eukaryotic RPB5 RNA polymerase subunit GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A3L08_05030 5263d567cc2b311fab56856f0e49ebac 82 Gene3D G3DSA:3.90.940.20 1 82 1.2E-36 T 23-10-2018 IPR035913 RPB5-like RNA polymerase subunit superfamily Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A3L08_05030 5263d567cc2b311fab56856f0e49ebac 82 SUPERFAMILY SSF55287 7 80 6.41E-28 T 23-10-2018 IPR035913 RPB5-like RNA polymerase subunit superfamily Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A3L08_06340 95f163c90d6cbec10e3f7dbad152d325 61 Pfam PF04021 Class III signal peptide 3 29 1.7E-9 T 23-10-2018 IPR007166 Class III signal peptide motif A3L08_02325 cbb4eca575f54b768c208c9495ef5549 322 SUPERFAMILY SSF52540 24 299 2.69E-20 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_02325 cbb4eca575f54b768c208c9495ef5549 322 Gene3D G3DSA:3.40.50.300 10 305 2.2E-16 T 23-10-2018 A3L08_08730 45eb529e75626ea4410c2fda28437162 252 SUPERFAMILY SSF51556 1 250 1.46E-54 T 23-10-2018 IPR032466 Metal-dependent hydrolase A3L08_08730 45eb529e75626ea4410c2fda28437162 252 TIGRFAM TIGR00010 TIGR00010: hydrolase, TatD family 1 249 2.2E-65 T 23-10-2018 IPR015991 Uncharacterised hydrolase TatD-type GO:0004536 A3L08_08730 45eb529e75626ea4410c2fda28437162 252 Pfam PF01026 TatD related DNase 2 248 6.1E-54 T 23-10-2018 IPR001130 TatD family GO:0016788 A3L08_08730 45eb529e75626ea4410c2fda28437162 252 PIRSF PIRSF005902 1 252 3.1E-55 T 23-10-2018 IPR001130 TatD family GO:0016788 A3L08_08730 45eb529e75626ea4410c2fda28437162 252 Gene3D G3DSA:3.20.20.140 1 251 6.9E-60 T 23-10-2018 A3L08_08730 45eb529e75626ea4410c2fda28437162 252 ProSitePatterns PS01091 TatD deoxyribonuclease family signature 3. 187 203 - T 23-10-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 A3L08_00675 c1da45ae8bc675522aad63fcba191a5a 90 Gene3D G3DSA:1.10.10.1100 1 67 4.4E-23 T 23-10-2018 A3L08_00675 c1da45ae8bc675522aad63fcba191a5a 90 Pfam PF04324 BFD-like [2Fe-2S] binding domain 6 58 1.0E-15 T 23-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain A3L08_09565 46127f4d6b57f9f52712155a3134651d 235 Hamap MF_02131 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase [mptE]. 7 224 36.179 T 23-10-2018 IPR027510 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, MptE GO:0003848|GO:0005524 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 A3L08_09565 46127f4d6b57f9f52712155a3134651d 235 Pfam PF01973 Protein of unknown function DUF115 49 186 1.1E-27 T 23-10-2018 IPR002826 6-hydroxymethylpterin diphosphokinase MptE-like A3L08_09565 46127f4d6b57f9f52712155a3134651d 235 SUPERFAMILY SSF63999 52 107 8.63E-9 T 23-10-2018 IPR036759 Thiamin pyrophosphokinase, catalytic domain superfamily GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 A3L08_09255 150993acf91f70eab5eedb0ee08d5acd 303 Pfam PF01751 Toprim domain 8 88 4.9E-8 T 23-10-2018 IPR006171 TOPRIM domain A3L08_09255 150993acf91f70eab5eedb0ee08d5acd 303 Gene3D G3DSA:3.40.1360.10 4 121 8.3E-7 T 23-10-2018 A3L08_09255 150993acf91f70eab5eedb0ee08d5acd 303 SMART SM00493 5 84 1.6E-7 T 23-10-2018 IPR006171 TOPRIM domain A3L08_02305 51fbd842514f0b9d5d46e947c98bba05 292 SUPERFAMILY SSF53448 3 268 9.25E-69 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L08_02305 51fbd842514f0b9d5d46e947c98bba05 292 TIGRFAM TIGR01099 galU: UTP--glucose-1-phosphate uridylyltransferase 3 263 1.3E-111 T 23-10-2018 IPR005771 UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type GO:0003983|GO:0006011 KEGG: 00040+2.7.7.9|KEGG: 00052+2.7.7.9|KEGG: 00500+2.7.7.9|KEGG: 00520+2.7.7.9|MetaCyc: PWY-3801|MetaCyc: PWY-6527|MetaCyc: PWY-7238|MetaCyc: PWY-7343|MetaCyc: PWY-7817 A3L08_02305 51fbd842514f0b9d5d46e947c98bba05 292 Pfam PF00483 Nucleotidyl transferase 5 266 7.8E-34 T 23-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 A3L08_02305 51fbd842514f0b9d5d46e947c98bba05 292 Gene3D G3DSA:3.90.550.10 1 289 2.7E-89 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L08_08445 8da85d42a4e26f36e3eaec3d2f10e96e 95 Pfam PF01883 Iron-sulfur cluster assembly protein 5 65 3.5E-6 T 23-10-2018 IPR002744 MIP18 family-like A3L08_08445 8da85d42a4e26f36e3eaec3d2f10e96e 95 Gene3D G3DSA:3.30.300.130 2 86 5.8E-8 T 23-10-2018 IPR034904 Fe-S cluster assembly domain superfamily A3L08_08445 8da85d42a4e26f36e3eaec3d2f10e96e 95 SUPERFAMILY SSF117916 4 67 2.91E-9 T 23-10-2018 IPR034904 Fe-S cluster assembly domain superfamily A3L08_02055 dc30c7bada0dda20bd6d8db58fbdfa5f 257 ProSitePatterns PS01240 Purine and other phosphorylases family 2 signature. 48 88 - T 23-10-2018 IPR018099 Purine phosphorylase, family 2, conserved site GO:0016763 A3L08_02055 dc30c7bada0dda20bd6d8db58fbdfa5f 257 Hamap MF_01963 S-methyl-5'-thioadenosine phosphorylase [mtnP]. 2 257 45.278 T 23-10-2018 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112|Reactome: R-HSA-8950505 A3L08_02055 dc30c7bada0dda20bd6d8db58fbdfa5f 257 Pfam PF01048 Phosphorylase superfamily 3 237 1.6E-49 T 23-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 A3L08_02055 dc30c7bada0dda20bd6d8db58fbdfa5f 257 Gene3D G3DSA:3.40.50.1580 1 257 2.2E-102 T 23-10-2018 A3L08_02055 dc30c7bada0dda20bd6d8db58fbdfa5f 257 TIGRFAM TIGR01694 MTAP: methylthioadenosine phosphorylase 3 238 5.6E-101 T 23-10-2018 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112|Reactome: R-HSA-8950505 A3L08_02055 dc30c7bada0dda20bd6d8db58fbdfa5f 257 SUPERFAMILY SSF53167 1 255 7.2E-92 T 23-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 A3L08_04275 db53d72382bd7b9d4d85ca0d2b7495db 201 Gene3D G3DSA:3.40.50.10490 7 201 5.8E-72 T 23-10-2018 A3L08_04275 db53d72382bd7b9d4d85ca0d2b7495db 201 TIGRFAM TIGR01012 uS2_euk_arch: ribosomal protein uS2 3 197 8.8E-100 T 23-10-2018 IPR005707 Ribosomal protein S2, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_04275 db53d72382bd7b9d4d85ca0d2b7495db 201 ProSitePatterns PS00963 Ribosomal protein S2 signature 2. 111 135 - T 23-10-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 A3L08_04275 db53d72382bd7b9d4d85ca0d2b7495db 201 PRINTS PR00395 Ribosomal protein S2 signature 128 139 5.9E-31 T 23-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L08_04275 db53d72382bd7b9d4d85ca0d2b7495db 201 PRINTS PR00395 Ribosomal protein S2 signature 111 128 5.9E-31 T 23-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L08_04275 db53d72382bd7b9d4d85ca0d2b7495db 201 PRINTS PR00395 Ribosomal protein S2 signature 8 26 5.9E-31 T 23-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L08_04275 db53d72382bd7b9d4d85ca0d2b7495db 201 PRINTS PR00395 Ribosomal protein S2 signature 86 103 5.9E-31 T 23-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L08_04275 db53d72382bd7b9d4d85ca0d2b7495db 201 PRINTS PR00395 Ribosomal protein S2 signature 149 163 5.9E-31 T 23-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L08_04275 db53d72382bd7b9d4d85ca0d2b7495db 201 PRINTS PR00395 Ribosomal protein S2 signature 38 47 5.9E-31 T 23-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L08_04275 db53d72382bd7b9d4d85ca0d2b7495db 201 Pfam PF00318 Ribosomal protein S2 12 104 8.4E-11 T 23-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L08_04275 db53d72382bd7b9d4d85ca0d2b7495db 201 Pfam PF00318 Ribosomal protein S2 110 174 5.7E-14 T 23-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L08_04275 db53d72382bd7b9d4d85ca0d2b7495db 201 Hamap MF_00291_A 30S ribosomal protein S2 [rpsB]. 1 198 48.533 T 23-10-2018 IPR023454 Ribosomal protein S2, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L08_04275 db53d72382bd7b9d4d85ca0d2b7495db 201 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 8 19 - T 23-10-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 A3L08_04275 db53d72382bd7b9d4d85ca0d2b7495db 201 SUPERFAMILY SSF52313 3 192 2.35E-62 T 23-10-2018 IPR023591 Ribosomal protein S2, flavodoxin-like domain superfamily A3L08_05165 8a21df39a2eb7816d51856b4cab3d156 219 Pfam PF02361 Cobalt transport protein 6 193 5.5E-25 T 23-10-2018 IPR003339 ABC/ECF transporter, transmembrane component A3L08_07450 6093674d25da63095ebf6c341b10dda8 266 Gene3D G3DSA:3.60.20.10 19 250 1.6E-17 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A3L08_07450 6093674d25da63095ebf6c341b10dda8 266 Pfam PF13230 Glutamine amidotransferases class-II 31 181 2.4E-9 T 23-10-2018 IPR026869 Putative glutamine amidotransferase type 2 A3L08_07450 6093674d25da63095ebf6c341b10dda8 266 SUPERFAMILY SSF56235 2 252 6.18E-18 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A3L08_08140 e4df0973087d6d699e2ecd16513b8f08 421 Pfam PF00232 Glycosyl hydrolase family 1 4 405 1.7E-92 T 23-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A3L08_08140 e4df0973087d6d699e2ecd16513b8f08 421 SUPERFAMILY SSF51445 4 411 1.83E-132 T 23-10-2018 IPR017853 Glycoside hydrolase superfamily A3L08_08140 e4df0973087d6d699e2ecd16513b8f08 421 Gene3D G3DSA:3.20.20.80 1 420 7.2E-154 T 23-10-2018 A3L08_08140 e4df0973087d6d699e2ecd16513b8f08 421 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 320 328 - T 23-10-2018 IPR018120 Glycoside hydrolase family 1, active site A3L08_08140 e4df0973087d6d699e2ecd16513b8f08 421 PRINTS PR00131 Glycosyl hydrolase family 1 signature 320 328 8.7E-22 T 23-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A3L08_08140 e4df0973087d6d699e2ecd16513b8f08 421 PRINTS PR00131 Glycosyl hydrolase family 1 signature 332 343 8.7E-22 T 23-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A3L08_08140 e4df0973087d6d699e2ecd16513b8f08 421 PRINTS PR00131 Glycosyl hydrolase family 1 signature 377 389 8.7E-22 T 23-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A3L08_08140 e4df0973087d6d699e2ecd16513b8f08 421 PRINTS PR00131 Glycosyl hydrolase family 1 signature 353 370 8.7E-22 T 23-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A3L08_08140 e4df0973087d6d699e2ecd16513b8f08 421 PRINTS PR00131 Glycosyl hydrolase family 1 signature 258 272 8.7E-22 T 23-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A3L08_01985 acf52231be3adeaaf90224c28b525cdf 440 SMART SM00881 6 100 1.1E-16 T 23-10-2018 IPR003781 CoA-binding GO:0048037 A3L08_01985 acf52231be3adeaaf90224c28b525cdf 440 SUPERFAMILY SSF51735 2 133 8.13E-22 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L08_01985 acf52231be3adeaaf90224c28b525cdf 440 Gene3D G3DSA:3.40.50.261 136 288 8.0E-61 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A3L08_01985 acf52231be3adeaaf90224c28b525cdf 440 Pfam PF13380 CoA binding domain 11 131 1.3E-16 T 23-10-2018 IPR003781 CoA-binding GO:0048037 A3L08_01985 acf52231be3adeaaf90224c28b525cdf 440 SUPERFAMILY SSF52210 130 286 4.97E-45 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A3L08_01985 acf52231be3adeaaf90224c28b525cdf 440 Gene3D G3DSA:3.40.50.261 289 440 5.4E-53 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A3L08_01985 acf52231be3adeaaf90224c28b525cdf 440 SUPERFAMILY SSF52210 292 438 2.88E-38 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A3L08_01985 acf52231be3adeaaf90224c28b525cdf 440 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 148 285 4.3E-58 T 23-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain A3L08_01985 acf52231be3adeaaf90224c28b525cdf 440 Gene3D G3DSA:3.40.50.720 1 127 1.3E-30 T 23-10-2018 A3L08_02345 d4dfe9e421e01d529400b735cf6869e7 476 SUPERFAMILY SSF53649 15 462 1.11E-39 T 23-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 A3L08_02345 d4dfe9e421e01d529400b735cf6869e7 476 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 17 423 1.0E-63 T 23-10-2018 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 A3L08_02345 d4dfe9e421e01d529400b735cf6869e7 476 Gene3D G3DSA:3.40.720.10 6 304 4.4E-51 T 23-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 A3L08_07250 3192b1c86e7930cb2763220b89a47b53 86 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 11 46 7.1E-6 T 23-10-2018 IPR002831 Transcription regulator TrmB, N-terminal A3L08_07250 3192b1c86e7930cb2763220b89a47b53 86 Gene3D G3DSA:1.10.10.10 1 69 5.8E-5 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L08_07250 3192b1c86e7930cb2763220b89a47b53 86 SUPERFAMILY SSF46785 5 50 1.11E-5 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L08_01150 8bb6975b1c4dff4f878af2fec5a06a8e 258 Pfam PF03437 BtpA family 5 254 2.2E-108 T 23-10-2018 IPR005137 Membrane complex biogenesis protein, BtpA family A3L08_01150 8bb6975b1c4dff4f878af2fec5a06a8e 258 ProDom PD011184 BTPA I PHOTOSYSTEM BIOGENESIS ASSEMBLY SGCQ TRIPHOSPHATASE NUCLEOSIDE PAE3553 ENZYME 28 199 2.0E-80 T 23-10-2018 IPR005137 Membrane complex biogenesis protein, BtpA family A3L08_01150 8bb6975b1c4dff4f878af2fec5a06a8e 258 TIGRFAM TIGR00259 thylakoid_BtpA: membrane complex biogenesis protein, BtpA family 6 256 1.2E-109 T 23-10-2018 IPR005137 Membrane complex biogenesis protein, BtpA family A3L08_01150 8bb6975b1c4dff4f878af2fec5a06a8e 258 PIRSF PIRSF005956 1 258 2.9E-98 T 23-10-2018 IPR005137 Membrane complex biogenesis protein, BtpA family A3L08_01150 8bb6975b1c4dff4f878af2fec5a06a8e 258 SUPERFAMILY SSF51366 11 251 2.59E-27 T 23-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 A3L08_03080 5f478fe3a659c73bc8f25cf3aa162695 383 Pfam PF00534 Glycosyl transferases group 1 180 350 1.8E-32 T 23-10-2018 IPR001296 Glycosyl transferase, family 1 A3L08_03080 5f478fe3a659c73bc8f25cf3aa162695 383 SUPERFAMILY SSF53756 47 372 4.04E-52 T 23-10-2018 A3L08_03080 5f478fe3a659c73bc8f25cf3aa162695 383 Gene3D G3DSA:3.40.50.2000 68 365 5.7E-45 T 23-10-2018 A3L08_03080 5f478fe3a659c73bc8f25cf3aa162695 383 Gene3D G3DSA:3.40.50.2000 178 356 5.7E-45 T 23-10-2018 A3L08_03360 85c9ab1b59795bfb78057f31c3539f9f 60 SUPERFAMILY SSF57829 13 59 3.11E-21 T 23-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 A3L08_03360 85c9ab1b59795bfb78057f31c3539f9f 60 Hamap MF_00777 30S ribosomal protein S27ae [rps27ae]. 13 58 19.75 T 23-10-2018 IPR022845 Ribosomal protein S27ae A3L08_03360 85c9ab1b59795bfb78057f31c3539f9f 60 Gene3D G3DSA:2.20.25.660 2 58 6.9E-20 T 23-10-2018 IPR038582 S27a-like superfamily Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 A3L08_03360 85c9ab1b59795bfb78057f31c3539f9f 60 SMART SM01402 13 55 1.2E-24 T 23-10-2018 IPR002906 Ribosomal protein S27a GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 A3L08_03360 85c9ab1b59795bfb78057f31c3539f9f 60 Pfam PF01599 Ribosomal protein S27a 14 55 3.1E-22 T 23-10-2018 IPR002906 Ribosomal protein S27a GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 A3L08_05200 bce686aff38285f2674606d6085ced8a 59 Pfam PF07650 KH domain 8 57 8.8E-5 T 23-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_05200 bce686aff38285f2674606d6085ced8a 59 Gene3D G3DSA:3.30.300.20 5 58 4.8E-9 T 23-10-2018 IPR015946 K homology domain-like, alpha/beta A3L08_05200 bce686aff38285f2674606d6085ced8a 59 SUPERFAMILY SSF54814 15 57 2.55E-7 T 23-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 A3L08_08810 eb85c83e6c080a1f94214fd3071dc4f6 70 ProDom PD005541 RIBOSOMAL RIBONUCLEOPROTEIN 40S S28 S28E 30S ACETYLATION S33 S33 CG15527 1 48 4.0E-8 T 23-10-2018 IPR000289 Ribosomal protein S28e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_08810 eb85c83e6c080a1f94214fd3071dc4f6 70 Hamap MF_00292 30S ribosomal protein S28e [rps28e]. 1 67 25.169 T 23-10-2018 IPR000289 Ribosomal protein S28e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_08810 eb85c83e6c080a1f94214fd3071dc4f6 70 Pfam PF01200 Ribosomal protein S28e 5 66 4.0E-29 T 23-10-2018 IPR000289 Ribosomal protein S28e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_08810 eb85c83e6c080a1f94214fd3071dc4f6 70 ProSitePatterns PS00961 Ribosomal protein S28e signature. 58 66 - T 23-10-2018 IPR028626 Ribosomal protein S28e conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_08810 eb85c83e6c080a1f94214fd3071dc4f6 70 SUPERFAMILY SSF50249 3 69 2.46E-25 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L08_08810 eb85c83e6c080a1f94214fd3071dc4f6 70 Gene3D G3DSA:2.40.50.140 1 70 2.8E-32 T 23-10-2018 A3L08_07165 fff7b24f5fc31cc6b21f6c39c165a013 71 Pfam PF01934 Protein of unknown function DUF86 15 66 1.0E-15 T 23-10-2018 IPR008201 Protein of unknown function DUF86 A3L08_01895 02b07b643bd035aad65b1779a4d0caa4 150 SUPERFAMILY SSF54909 65 147 1.22E-16 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel A3L08_01895 02b07b643bd035aad65b1779a4d0caa4 150 Pfam PF13412 Winged helix-turn-helix DNA-binding 5 52 3.4E-14 T 23-10-2018 A3L08_01895 02b07b643bd035aad65b1779a4d0caa4 150 Gene3D G3DSA:3.30.70.920 59 150 2.7E-22 T 23-10-2018 A3L08_01895 02b07b643bd035aad65b1779a4d0caa4 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 21 32 1.0E-12 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L08_01895 02b07b643bd035aad65b1779a4d0caa4 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 32 51 1.0E-12 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L08_01895 02b07b643bd035aad65b1779a4d0caa4 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 5 21 1.0E-12 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A3L08_01895 02b07b643bd035aad65b1779a4d0caa4 150 SMART SM00344 5 114 3.9E-42 T 23-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A3L08_01895 02b07b643bd035aad65b1779a4d0caa4 150 Pfam PF01037 Lrp/AsnC ligand binding domain 80 142 2.0E-14 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A3L08_01895 02b07b643bd035aad65b1779a4d0caa4 150 Gene3D G3DSA:1.10.10.10 2 56 6.8E-19 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L08_01895 02b07b643bd035aad65b1779a4d0caa4 150 SUPERFAMILY SSF46785 4 63 2.54E-11 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L08_08980 4f090221007bb611122d1b13f2f017b5 612 SUPERFAMILY SSF161098 333 605 1.96E-40 T 23-10-2018 IPR035906 MetI-like superfamily A3L08_08980 4f090221007bb611122d1b13f2f017b5 612 SUPERFAMILY SSF161098 23 312 3.92E-42 T 23-10-2018 IPR035906 MetI-like superfamily A3L08_08980 4f090221007bb611122d1b13f2f017b5 612 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 116 305 1.1E-12 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A3L08_08980 4f090221007bb611122d1b13f2f017b5 612 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 419 601 8.4E-15 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A3L08_08980 4f090221007bb611122d1b13f2f017b5 612 Gene3D G3DSA:1.10.3720.10 19 317 1.4E-48 T 23-10-2018 IPR035906 MetI-like superfamily A3L08_08980 4f090221007bb611122d1b13f2f017b5 612 Gene3D G3DSA:1.10.3720.10 336 607 1.5E-36 T 23-10-2018 IPR035906 MetI-like superfamily A3L08_05635 3500e81c788cd92e096a73026f35c486 323 Gene3D G3DSA:3.30.70.890 155 271 2.6E-12 T 23-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily A3L08_05635 3500e81c788cd92e096a73026f35c486 323 Pfam PF00288 GHMP kinases N terminal domain 75 136 4.4E-7 T 23-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 A3L08_05635 3500e81c788cd92e096a73026f35c486 323 Pfam PF08544 GHMP kinases C terminal 203 272 6.2E-5 T 23-10-2018 IPR013750 GHMP kinase, C-terminal domain A3L08_05635 3500e81c788cd92e096a73026f35c486 323 TIGRFAM TIGR00144 beta_RFAP_syn: beta-ribofuranosylaminobenzene 5'-phosphate synthase family 1 307 6.8E-46 T 23-10-2018 IPR004422 GHMP kinase group 1 KEGG: 00790+2.4.2.54|MetaCyc: PWY-6148 A3L08_05635 3500e81c788cd92e096a73026f35c486 323 Gene3D G3DSA:3.30.230.10 21 154 2.6E-12 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A3L08_05635 3500e81c788cd92e096a73026f35c486 323 SUPERFAMILY SSF54211 4 149 1.06E-18 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A3L08_05635 3500e81c788cd92e096a73026f35c486 323 PIRSF PIRSF004884 1 309 3.3E-101 T 23-10-2018 IPR004422 GHMP kinase group 1 KEGG: 00790+2.4.2.54|MetaCyc: PWY-6148 A3L08_07910 2c2a7df6d0299740df5fe69459666f7e 250 Gene3D G3DSA:3.40.50.1220 12 242 4.4E-93 T 23-10-2018 A3L08_07910 2c2a7df6d0299740df5fe69459666f7e 250 Hamap MF_01121 NAD-dependent protein deacylase [cobB]. 13 248 61.789 T 23-10-2018 IPR027546 Sirtuin, class III GO:0036054|GO:0036055|GO:0070403 Reactome: R-HSA-2151201 A3L08_07910 2c2a7df6d0299740df5fe69459666f7e 250 Gene3D G3DSA:3.30.1600.10 29 168 4.4E-93 T 23-10-2018 IPR026591 Sirtuin, catalytic core small domain superfamily A3L08_07910 2c2a7df6d0299740df5fe69459666f7e 250 SUPERFAMILY SSF52467 2 246 7.64E-92 T 23-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily A3L08_07910 2c2a7df6d0299740df5fe69459666f7e 250 Pfam PF02146 Sir2 family 20 198 2.4E-59 T 23-10-2018 IPR003000 Sirtuin family GO:0070403 A3L08_03670 d4caab7213ea53c56750bf39383a9d2f 347 Gene3D G3DSA:3.60.70.12 1 346 2.1E-136 T 23-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 A3L08_03670 d4caab7213ea53c56750bf39383a9d2f 347 SUPERFAMILY SSF56266 2 342 2.54E-100 T 23-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 A3L08_03670 d4caab7213ea53c56750bf39383a9d2f 347 Pfam PF03576 Peptidase family S58 19 324 8.5E-111 T 23-10-2018 IPR005321 Peptidase S58, DmpA A3L08_06330 b5b03e1218ff1755e02f100170d9ea5e 735 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 62 194 1.4E-17 T 23-10-2018 IPR038731 Glycosyltransferase RgtA/B/C/D-like A3L08_07565 70f9c279fa63b2e2117c91a7271b0f67 309 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L08_07565 70f9c279fa63b2e2117c91a7271b0f67 309 SMART SM00382 30 213 3.3E-11 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L08_07565 70f9c279fa63b2e2117c91a7271b0f67 309 SUPERFAMILY SSF52540 5 227 1.63E-61 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_07565 70f9c279fa63b2e2117c91a7271b0f67 309 Gene3D G3DSA:3.40.50.300 1 238 2.3E-67 T 23-10-2018 A3L08_07565 70f9c279fa63b2e2117c91a7271b0f67 309 Pfam PF13732 Domain of unknown function (DUF4162) 218 302 1.5E-7 T 23-10-2018 IPR025302 Domain of unknown function DUF4162 A3L08_07565 70f9c279fa63b2e2117c91a7271b0f67 309 Pfam PF00005 ABC transporter 22 165 3.2E-31 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L08_04345 84b0d648b1e311992d1ee38e3ec93394 433 Gene3D G3DSA:1.25.40.10 278 407 9.3E-11 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A3L08_04345 84b0d648b1e311992d1ee38e3ec93394 433 Gene3D G3DSA:1.25.40.10 3 179 6.9E-17 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A3L08_00910 e9eacd1df65d8bd7651aa74cb4383506 158 TIGRFAM TIGR01681 HAD-SF-IIIC: HAD phosphatase, family IIIC 3 130 1.2E-15 T 23-10-2018 IPR010033 HAD-superfamily phosphatase, subfamily IIIC A3L08_00910 e9eacd1df65d8bd7651aa74cb4383506 158 TIGRFAM TIGR01685 MDP-1: magnesium-dependent phosphatase-1 2 152 1.6E-27 T 23-10-2018 IPR010036 Magnesium-dependent phosphatase-1, eukaryotic/archaeal-type GO:0016791 A3L08_00910 e9eacd1df65d8bd7651aa74cb4383506 158 Pfam PF12689 Acid Phosphatase 1 64 2.5E-7 T 23-10-2018 IPR010036 Magnesium-dependent phosphatase-1, eukaryotic/archaeal-type GO:0016791 A3L08_00910 e9eacd1df65d8bd7651aa74cb4383506 158 Gene3D G3DSA:3.40.50.1000 1 157 2.2E-26 T 23-10-2018 IPR023214 HAD superfamily A3L08_00910 e9eacd1df65d8bd7651aa74cb4383506 158 SUPERFAMILY SSF56784 2 125 3.47E-17 T 23-10-2018 IPR036412 HAD-like superfamily A3L08_09805 74d92e928315789a16a6012d77f66b79 188 SMART SM00471 30 147 3.7E-11 T 23-10-2018 IPR003607 HD/PDEase domain A3L08_09805 74d92e928315789a16a6012d77f66b79 188 Pfam PF13023 HD domain 13 152 9.5E-29 T 23-10-2018 IPR006674 HD domain A3L08_09805 74d92e928315789a16a6012d77f66b79 188 SUPERFAMILY SSF109604 5 171 9.11E-41 T 23-10-2018 A3L08_09805 74d92e928315789a16a6012d77f66b79 188 Gene3D G3DSA:1.10.3210.10 2 185 1.4E-58 T 23-10-2018 A3L08_06040 91d2e7fba0777bceecab0eaaaa77be2e 215 SMART SM00879 3 190 2.4E-15 T 23-10-2018 IPR007109 Brix domain A3L08_06040 91d2e7fba0777bceecab0eaaaa77be2e 215 SUPERFAMILY SSF52954 1 193 1.11E-34 T 23-10-2018 A3L08_06040 91d2e7fba0777bceecab0eaaaa77be2e 215 Gene3D G3DSA:3.40.50.10480 1 186 5.4E-33 T 23-10-2018 A3L08_06040 91d2e7fba0777bceecab0eaaaa77be2e 215 Hamap MF_00699 Probable Brix domain-containing ribosomal biogenesis protein. 2 191 29.326 T 23-10-2018 IPR023548 Probable Brix domain-containing ribosomal biogenesis protein A3L08_04795 26b8ada07357d4f4b0a6e21599597cdf 272 Hamap MF_00562 D-aminoacyl-tRNA deacylase [dtdA]. 1 271 35.95 T 23-10-2018 IPR018033 D-aminoacyl-tRNA deacylase, archaea GO:0016788|GO:0019478|GO:0051499 A3L08_04795 26b8ada07357d4f4b0a6e21599597cdf 272 Gene3D G3DSA:3.40.50.10700 187 272 1.6E-30 T 23-10-2018 A3L08_04795 26b8ada07357d4f4b0a6e21599597cdf 272 Pfam PF04414 D-aminoacyl-tRNA deacylase 68 269 1.3E-68 T 23-10-2018 IPR007508 D-aminoacyl-tRNA deacylase DtdA GO:0016788|GO:0051499 A3L08_04795 26b8ada07357d4f4b0a6e21599597cdf 272 Gene3D G3DSA:3.40.630.50 1 186 3.1E-71 T 23-10-2018 A3L08_04795 26b8ada07357d4f4b0a6e21599597cdf 272 PIRSF PIRSF016210 1 272 3.0E-83 T 23-10-2018 IPR018033 D-aminoacyl-tRNA deacylase, archaea GO:0016788|GO:0019478|GO:0051499 A3L08_04795 26b8ada07357d4f4b0a6e21599597cdf 272 SUPERFAMILY SSF142535 1 270 6.54E-89 T 23-10-2018 A3L08_09585 bb2780df98ee4dd32f8ea34096c6bec4 249 Gene3D G3DSA:3.60.15.10 1 249 4.4E-51 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L08_09585 bb2780df98ee4dd32f8ea34096c6bec4 249 SMART SM00849 37 215 3.6E-17 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L08_09585 bb2780df98ee4dd32f8ea34096c6bec4 249 SUPERFAMILY SSF56281 1 247 1.4E-42 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L08_09585 bb2780df98ee4dd32f8ea34096c6bec4 249 Pfam PF12706 Beta-lactamase superfamily domain 50 216 5.2E-20 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L08_06505 195bc13d7ac91c3676087bb96f19c0a7 164 SUPERFAMILY SSF54862 4 149 3.98E-50 T 23-10-2018 A3L08_06505 195bc13d7ac91c3676087bb96f19c0a7 164 Gene3D G3DSA:3.30.70.20 36 154 2.9E-36 T 23-10-2018 A3L08_06505 195bc13d7ac91c3676087bb96f19c0a7 164 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 78 89 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L08_06505 195bc13d7ac91c3676087bb96f19c0a7 164 Pfam PF13247 4Fe-4S dicluster domain 39 130 5.3E-24 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L08_06505 195bc13d7ac91c3676087bb96f19c0a7 164 Gene3D G3DSA:3.30.70.20 1 35 6.1E-6 T 23-10-2018 A3L08_03715 4c572034ec7300257c507b094ba029b9 158 Pfam PF11848 Domain of unknown function (DUF3368) 111 153 2.6E-7 T 23-10-2018 IPR021799 Protein of unknown function DUF3368 A3L08_06620 f03bd0b304fb5664544f9433b63c5d14 190 SUPERFAMILY SSF54631 67 185 1.25E-27 T 23-10-2018 A3L08_06620 f03bd0b304fb5664544f9433b63c5d14 190 Pfam PF00571 CBS domain 134 184 3.5E-7 T 23-10-2018 IPR000644 CBS domain A3L08_06620 f03bd0b304fb5664544f9433b63c5d14 190 Pfam PF00571 CBS domain 70 121 4.1E-12 T 23-10-2018 IPR000644 CBS domain A3L08_06620 f03bd0b304fb5664544f9433b63c5d14 190 Pfam PF01381 Helix-turn-helix 13 60 1.4E-14 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A3L08_06620 f03bd0b304fb5664544f9433b63c5d14 190 SUPERFAMILY SSF47413 11 60 1.47E-14 T 23-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A3L08_06620 f03bd0b304fb5664544f9433b63c5d14 190 Gene3D G3DSA:1.10.260.40 10 63 7.8E-17 T 23-10-2018 A3L08_06620 f03bd0b304fb5664544f9433b63c5d14 190 SMART SM00116 77 124 5.3E-6 T 23-10-2018 IPR000644 CBS domain A3L08_06620 f03bd0b304fb5664544f9433b63c5d14 190 SMART SM00116 141 187 0.064 T 23-10-2018 IPR000644 CBS domain A3L08_06620 f03bd0b304fb5664544f9433b63c5d14 190 SMART SM00530 12 68 2.1E-14 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A3L08_06620 f03bd0b304fb5664544f9433b63c5d14 190 PIRSF PIRSF037253 2 190 1.2E-81 T 23-10-2018 IPR017158 Transcription regulator, CBS domain-containing, predicted A3L08_06620 f03bd0b304fb5664544f9433b63c5d14 190 Gene3D G3DSA:3.10.580.10 64 186 1.1E-27 T 23-10-2018 A3L08_03250 094b38d39a479d38fb76f0eba3c1c469 143 Pfam PF00731 AIR carboxylase 2 142 9.5E-56 T 23-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 A3L08_03250 094b38d39a479d38fb76f0eba3c1c469 143 Gene3D G3DSA:3.40.50.7700 2 143 4.7E-61 T 23-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 A3L08_03250 094b38d39a479d38fb76f0eba3c1c469 143 SUPERFAMILY SSF52255 2 141 4.32E-52 T 23-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 A3L08_03250 094b38d39a479d38fb76f0eba3c1c469 143 PIRSF PIRSF001338 1 143 3.9E-58 T 23-10-2018 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 A3L08_03250 094b38d39a479d38fb76f0eba3c1c469 143 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 3 143 25.494 T 23-10-2018 IPR033747 Class I PurE A3L08_03250 094b38d39a479d38fb76f0eba3c1c469 143 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 3 141 8.7E-55 T 23-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 A3L08_03250 094b38d39a479d38fb76f0eba3c1c469 143 SMART SM01001 1 143 3.1E-70 T 23-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 A3L08_04845 fb9015f80f4898f1cb20ac49da5ffbd0 67 SUPERFAMILY SSF47113 3 66 1.59E-20 T 23-10-2018 IPR009072 Histone-fold GO:0046982 A3L08_04845 fb9015f80f4898f1cb20ac49da5ffbd0 67 Gene3D G3DSA:1.10.20.10 1 67 3.5E-25 T 23-10-2018 IPR009072 Histone-fold GO:0046982 A3L08_04845 fb9015f80f4898f1cb20ac49da5ffbd0 67 Pfam PF00808 Histone-like transcription factor (CBF/NF-Y) and archaeal histone 2 65 4.0E-21 T 23-10-2018 IPR003958 Transcription factor CBF/NF-Y/archaeal histone domain A3L08_08390 8891a4c01b05b27b2fc42834814f3961 219 Gene3D G3DSA:3.40.50.11570 6 216 2.1E-49 T 23-10-2018 A3L08_08390 8891a4c01b05b27b2fc42834814f3961 219 Pfam PF03192 Pyrococcus protein of unknown function, DUF257 11 210 1.2E-39 T 23-10-2018 IPR005489 Protein of unknown function DUF257 A3L08_00510 a32bfdd71122bb6ef9b197fd4129a6cd 167 Gene3D G3DSA:3.40.630.30 1 159 2.5E-49 T 23-10-2018 A3L08_00510 a32bfdd71122bb6ef9b197fd4129a6cd 167 SUPERFAMILY SSF55729 8 154 1.8E-28 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase A3L08_00510 a32bfdd71122bb6ef9b197fd4129a6cd 167 Pfam PF00583 Acetyltransferase (GNAT) family 20 141 3.4E-19 T 23-10-2018 IPR000182 GNAT domain A3L08_04805 4a69c28077329aa5c743d27c20a88729 61 Gene3D G3DSA:1.20.5.820 1 61 2.5E-21 T 23-10-2018 IPR023391 Protein translocase SecE domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A3L08_04805 4a69c28077329aa5c743d27c20a88729 61 ProSitePatterns PS01067 Protein secE/sec61-gamma signature. 11 39 - T 23-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A3L08_04805 4a69c28077329aa5c743d27c20a88729 61 Hamap MF_00422 Protein translocase subunit SecE [secE]. 6 60 10.918 T 23-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A3L08_04805 4a69c28077329aa5c743d27c20a88729 61 SUPERFAMILY SSF103456 3 58 3.79E-18 T 23-10-2018 IPR023391 Protein translocase SecE domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A3L08_04805 4a69c28077329aa5c743d27c20a88729 61 TIGRFAM TIGR00327 secE_euk_arch: protein translocase SEC61 complex gamma subunit, archaeal and eukaryotic 5 60 1.5E-16 T 23-10-2018 IPR008158 Protein translocase SEC61 complex, gamma subunit GO:0015031|GO:0015450|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A3L08_00125 cca1d97cbf2366a52ba80f3ee0a013eb 253 Gene3D G3DSA:3.40.50.300 1 242 4.8E-70 T 23-10-2018 A3L08_00125 cca1d97cbf2366a52ba80f3ee0a013eb 253 SUPERFAMILY SSF52540 1 221 1.0E-63 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_00125 cca1d97cbf2366a52ba80f3ee0a013eb 253 Pfam PF00005 ABC transporter 18 161 2.5E-28 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L08_00125 cca1d97cbf2366a52ba80f3ee0a013eb 253 SMART SM00382 26 209 5.7E-14 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L08_02925 18a619c3f8f0357f401fdcbaeff23d33 184 SUPERFAMILY SSF55144 1 182 1.66E-46 T 23-10-2018 IPR009097 Cyclic phosphodiesterase A3L08_02925 18a619c3f8f0357f401fdcbaeff23d33 184 Hamap MF_01940 RNA 2',3'-cyclic phosphodiesterase [thpR]. 1 182 27.329 T 23-10-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 A3L08_02925 18a619c3f8f0357f401fdcbaeff23d33 184 Gene3D G3DSA:3.90.1140.10 1 184 6.0E-67 T 23-10-2018 A3L08_02925 18a619c3f8f0357f401fdcbaeff23d33 184 TIGRFAM TIGR02258 2_5_ligase: 2'-5' RNA ligase 1 182 6.1E-55 T 23-10-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 A3L08_02925 18a619c3f8f0357f401fdcbaeff23d33 184 Pfam PF02834 LigT like Phosphoesterase 7 91 1.4E-20 T 23-10-2018 IPR014051 Phosphoesterase, HXTX A3L08_02925 18a619c3f8f0357f401fdcbaeff23d33 184 Pfam PF02834 LigT like Phosphoesterase 98 174 8.0E-14 T 23-10-2018 IPR014051 Phosphoesterase, HXTX A3L08_03985 35f87e5ceb106a307f533e3cc782cd82 76 Gene3D G3DSA:3.30.930.10 8 73 1.3E-9 T 23-10-2018 A3L08_03985 35f87e5ceb106a307f533e3cc782cd82 76 SUPERFAMILY SSF55681 24 70 3.29E-9 T 23-10-2018 A3L08_03985 35f87e5ceb106a307f533e3cc782cd82 76 Pfam PF00152 tRNA synthetases class II (D, K and N) 19 68 1.1E-6 T 23-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L08_00295 f3de1bc6866e02bfe7bfd4b3a6e6a8f4 333 Gene3D G3DSA:1.10.3720.10 92 327 2.7E-26 T 23-10-2018 IPR035906 MetI-like superfamily A3L08_00295 f3de1bc6866e02bfe7bfd4b3a6e6a8f4 333 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 116 333 2.3E-43 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A3L08_00295 f3de1bc6866e02bfe7bfd4b3a6e6a8f4 333 SUPERFAMILY SSF161098 96 320 9.97E-17 T 23-10-2018 IPR035906 MetI-like superfamily A3L08_04780 17727594687c20d36edcf90fd994422b 777 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 156 490 1.8E-56 T 23-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit A3L08_04780 17727594687c20d36edcf90fd994422b 777 TIGRFAM TIGR02123 TRAP_fused: TRAP transporter, 4TM/12TM fusion protein 73 490 2.2E-113 T 23-10-2018 IPR011853 TRAP C4-dicarboxylate transport system permease, fused DctM-DctQ A3L08_02185 6bbbc421b3ae530ae774068147e0e54f 354 Pfam PF00482 Type II secretion system (T2SS), protein F 186 310 1.5E-23 T 23-10-2018 IPR018076 Type II secretion system F domain A3L08_02185 6bbbc421b3ae530ae774068147e0e54f 354 Gene3D G3DSA:1.20.81.30 172 286 5.8E-12 T 23-10-2018 A3L08_08340 c70b109058aa238ff21cfda85cab8759 100 Pfam PF02915 Rubrerythrin 24 92 1.5E-7 T 23-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 A3L08_08340 c70b109058aa238ff21cfda85cab8759 100 Gene3D G3DSA:1.20.1260.10 4 75 2.5E-10 T 23-10-2018 IPR012347 Ferritin-like A3L08_08340 c70b109058aa238ff21cfda85cab8759 100 SUPERFAMILY SSF47240 6 85 8.13E-20 T 23-10-2018 IPR009078 Ferritin-like superfamily A3L08_06045 7fe180201d52d5cde8ff6547714158dd 49 Hamap MF_00615 DNA-directed RNA polymerase subunit P [rpoP]. 6 49 16.941 T 23-10-2018 IPR023464 DNA-directed RNA polymerase subunit P (Rpo12) GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A3L08_06045 7fe180201d52d5cde8ff6547714158dd 49 SUPERFAMILY SSF63393 4 48 7.32E-13 T 23-10-2018 IPR029040 RNA polymerase subunit RPABC4/transcription elongation factor Spt4 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-75955 A3L08_06045 7fe180201d52d5cde8ff6547714158dd 49 Pfam PF03604 DNA directed RNA polymerase, 7 kDa subunit 6 39 7.4E-11 T 23-10-2018 IPR006591 RNA polymerase archaeal subunit P/eukaryotic subunit RPABC4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A3L08_06045 7fe180201d52d5cde8ff6547714158dd 49 SMART SM00659 4 49 1.2E-20 T 23-10-2018 IPR006591 RNA polymerase archaeal subunit P/eukaryotic subunit RPABC4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A3L08_06045 7fe180201d52d5cde8ff6547714158dd 49 Gene3D G3DSA:2.20.28.30 1 49 1.3E-23 T 23-10-2018 A3L08_07870 a420d0f6d62aaa5c0312a557df91d21c 440 Gene3D G3DSA:3.30.2290.10 3 209 9.5E-16 T 23-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal A3L08_07870 a420d0f6d62aaa5c0312a557df91d21c 440 Pfam PF01523 Putative modulator of DNA gyrase 21 303 1.2E-48 T 23-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 A3L08_07870 a420d0f6d62aaa5c0312a557df91d21c 440 SUPERFAMILY SSF111283 3 436 7.32E-93 T 23-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 A3L08_00880 b0cd1fd25cc1fd141c303afa55db5c7f 194 SUPERFAMILY SSF53323 2 192 2.75E-29 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 A3L08_00880 b0cd1fd25cc1fd141c303afa55db5c7f 194 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 11 190 7.4E-36 T 23-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 A3L08_00880 b0cd1fd25cc1fd141c303afa55db5c7f 194 Gene3D G3DSA:3.40.920.10 1 194 1.4E-37 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 A3L08_08290 297c72ea616b18622cca5289c0429834 268 SUPERFAMILY SSF55961 1 132 4.46E-6 T 23-10-2018 A3L08_07895 57271d4862b4ea0374af368d90734ee9 182 SUPERFAMILY SSF88697 3 101 2.61E-19 T 23-10-2018 IPR015947 PUA-like superfamily A3L08_07895 57271d4862b4ea0374af368d90734ee9 182 SMART SM01022 1 102 1.5E-18 T 23-10-2018 IPR007374 ASCH domain A3L08_07895 57271d4862b4ea0374af368d90734ee9 182 Pfam PF04266 ASCH domain 4 101 1.6E-19 T 23-10-2018 IPR007374 ASCH domain A3L08_07005 80dc7c282b29ab7306866a4c30a86f6d 228 Gene3D G3DSA:3.40.50.720 1 228 3.9E-63 T 23-10-2018 A3L08_07005 80dc7c282b29ab7306866a4c30a86f6d 228 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 137 165 - T 23-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A3L08_07005 80dc7c282b29ab7306866a4c30a86f6d 228 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 1.1E-16 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L08_07005 80dc7c282b29ab7306866a4c30a86f6d 228 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 169 186 1.1E-16 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L08_07005 80dc7c282b29ab7306866a4c30a86f6d 228 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 1.1E-16 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L08_07005 80dc7c282b29ab7306866a4c30a86f6d 228 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 1.1E-16 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L08_07005 80dc7c282b29ab7306866a4c30a86f6d 228 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 1.1E-16 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L08_07005 80dc7c282b29ab7306866a4c30a86f6d 228 SUPERFAMILY SSF51735 2 221 1.84E-55 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L08_07005 80dc7c282b29ab7306866a4c30a86f6d 228 Pfam PF00106 short chain dehydrogenase 2 185 5.5E-44 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A3L08_03385 5995692ba44ce288b4c144e8b9fbb026 178 Gene3D G3DSA:3.90.80.10 1 178 4.1E-75 T 23-10-2018 IPR036649 Inorganic pyrophosphatase superfamily GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 A3L08_03385 5995692ba44ce288b4c144e8b9fbb026 178 ProSitePatterns PS00387 Inorganic pyrophosphatase signature. 66 72 - T 23-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 A3L08_03385 5995692ba44ce288b4c144e8b9fbb026 178 Hamap MF_00209 Inorganic pyrophosphatase [ppa]. 15 171 36.541 T 23-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 A3L08_03385 5995692ba44ce288b4c144e8b9fbb026 178 Pfam PF00719 Inorganic pyrophosphatase 20 171 4.4E-58 T 23-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 A3L08_03385 5995692ba44ce288b4c144e8b9fbb026 178 SUPERFAMILY SSF50324 1 176 7.46E-68 T 23-10-2018 IPR036649 Inorganic pyrophosphatase superfamily GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 A3L08_04750 6b6da168c9f11bd0074f3b1a9855a91d 393 Gene3D G3DSA:3.50.50.60 3 338 3.7E-107 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L08_04750 6b6da168c9f11bd0074f3b1a9855a91d 393 Hamap MF_01287 Digeranylgeranylglycerophospholipid reductase. 1 387 39.611 T 23-10-2018 IPR023590 Digeranylgeranylglycerophospholipid reductase GO:0016628|GO:0045550|GO:0046467|GO:0055114 KEGG: 00564+1.3.7.11|MetaCyc: PWY-6349 A3L08_04750 6b6da168c9f11bd0074f3b1a9855a91d 393 SUPERFAMILY SSF51905 1 331 1.06E-39 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L08_04750 6b6da168c9f11bd0074f3b1a9855a91d 393 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 266 281 6.3E-10 T 23-10-2018 A3L08_04750 6b6da168c9f11bd0074f3b1a9855a91d 393 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 144 159 6.3E-10 T 23-10-2018 A3L08_04750 6b6da168c9f11bd0074f3b1a9855a91d 393 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 6.3E-10 T 23-10-2018 A3L08_04750 6b6da168c9f11bd0074f3b1a9855a91d 393 Pfam PF05834 Lycopene cyclase protein 4 332 1.3E-13 T 23-10-2018 A3L08_04750 6b6da168c9f11bd0074f3b1a9855a91d 393 Gene3D G3DSA:3.30.9.10 69 356 3.7E-107 T 23-10-2018 A3L08_04750 6b6da168c9f11bd0074f3b1a9855a91d 393 TIGRFAM TIGR02032 GG-red-SF: geranylgeranyl reductase family 3 301 5.6E-76 T 23-10-2018 IPR011777 Geranylgeranyl reductase family GO:0016628|GO:0055114 A3L08_01640 7e0157d21b77019d4fd460be26aadd1f 158 PRINTS PR00728 Eukaryotic signal peptidase (S26B) family signature 39 54 1.2E-8 T 23-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 A3L08_01640 7e0157d21b77019d4fd460be26aadd1f 158 PRINTS PR00728 Eukaryotic signal peptidase (S26B) family signature 104 115 1.2E-8 T 23-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 A3L08_01640 7e0157d21b77019d4fd460be26aadd1f 158 SUPERFAMILY SSF51306 36 92 1.48E-10 T 23-10-2018 IPR036286 LexA/Signal peptidase-like superfamily A3L08_01640 7e0157d21b77019d4fd460be26aadd1f 158 TIGRFAM TIGR02228 sigpep_I_arch: signal peptidase I 5 151 2.9E-34 T 23-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 A3L08_01640 7e0157d21b77019d4fd460be26aadd1f 158 Pfam PF00717 Peptidase S24-like 39 89 1.6E-6 T 23-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C A3L08_02390 f7dc7d0b79c7ff71d9b48acb9556be59 231 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 92 188 6.1E-11 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A3L08_02390 f7dc7d0b79c7ff71d9b48acb9556be59 231 Pfam PF13419 Haloacid dehalogenase-like hydrolase 3 194 2.0E-20 T 23-10-2018 A3L08_02390 f7dc7d0b79c7ff71d9b48acb9556be59 231 SUPERFAMILY SSF56784 3 222 6.8E-37 T 23-10-2018 IPR036412 HAD-like superfamily A3L08_02390 f7dc7d0b79c7ff71d9b48acb9556be59 231 Gene3D G3DSA:1.10.150.520 14 96 4.4E-38 T 23-10-2018 A3L08_02390 f7dc7d0b79c7ff71d9b48acb9556be59 231 Gene3D G3DSA:3.40.50.1000 3 216 4.4E-38 T 23-10-2018 IPR023214 HAD superfamily A3L08_03795 090451b1b62d793c60e46916cebc939f 178 SUPERFAMILY SSF52499 4 178 7.59E-55 T 23-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 A3L08_03795 090451b1b62d793c60e46916cebc939f 178 Pfam PF00857 Isochorismatase family 5 177 2.2E-45 T 23-10-2018 IPR000868 Isochorismatase-like GO:0003824 A3L08_03795 090451b1b62d793c60e46916cebc939f 178 Gene3D G3DSA:3.40.50.850 1 178 1.7E-71 T 23-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 A3L08_05625 27410db22b9c436d89d5ad545cd38bef 272 Gene3D G3DSA:3.20.20.20 3 271 2.4E-90 T 23-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A3L08_05625 27410db22b9c436d89d5ad545cd38bef 272 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 12 266 1.8E-73 T 23-10-2018 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 A3L08_05625 27410db22b9c436d89d5ad545cd38bef 272 SUPERFAMILY SSF51717 6 269 1.96E-80 T 23-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A3L08_05625 27410db22b9c436d89d5ad545cd38bef 272 Pfam PF00809 Pterin binding enzyme 14 252 5.0E-62 T 23-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A3L08_03445 13f9d2c3507a6a86db7f2cf4b1ca9eef 562 SUPERFAMILY SSF52025 94 198 4.19E-7 T 23-10-2018 A3L08_03445 13f9d2c3507a6a86db7f2cf4b1ca9eef 562 Pfam PF02225 PA domain 118 185 9.5E-6 T 23-10-2018 IPR003137 PA domain A3L08_03445 13f9d2c3507a6a86db7f2cf4b1ca9eef 562 Gene3D G3DSA:3.40.630.10 28 405 5.3E-57 T 23-10-2018 A3L08_03445 13f9d2c3507a6a86db7f2cf4b1ca9eef 562 Pfam PF04389 Peptidase family M28 228 412 2.7E-18 T 23-10-2018 IPR007484 Peptidase M28 A3L08_03445 13f9d2c3507a6a86db7f2cf4b1ca9eef 562 SUPERFAMILY SSF53187 9 420 1.26E-31 T 23-10-2018 A3L08_03445 13f9d2c3507a6a86db7f2cf4b1ca9eef 562 Gene3D G3DSA:3.50.30.30 73 208 5.3E-57 T 23-10-2018 A3L08_00145 ebab8566dd996cd0da6467c32bd98a48 200 Gene3D G3DSA:3.30.1360.30 81 191 2.0E-44 T 23-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 A3L08_00145 ebab8566dd996cd0da6467c32bd98a48 200 Pfam PF14544 Domain of unknown function (DUF4443) 80 189 1.2E-55 T 23-10-2018 IPR029349 Domain of unknown function DUF4443 A3L08_00145 ebab8566dd996cd0da6467c32bd98a48 200 SUPERFAMILY SSF46785 18 76 8.49E-10 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L08_00145 ebab8566dd996cd0da6467c32bd98a48 200 Gene3D G3DSA:1.10.10.10 1 80 7.3E-23 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L08_00145 ebab8566dd996cd0da6467c32bd98a48 200 SUPERFAMILY SSF55261 88 198 7.41E-39 T 23-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 A3L08_04160 1014ffa6fb050e8e21f85d6ab18d231f 148 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 29 146 8.3E-19 T 23-10-2018 IPR021131 Ribosomal protein L18e/L15P A3L08_04160 1014ffa6fb050e8e21f85d6ab18d231f 148 Gene3D G3DSA:3.100.10.10 63 148 1.1E-21 T 23-10-2018 A3L08_04160 1014ffa6fb050e8e21f85d6ab18d231f 148 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 1 148 14.108 T 23-10-2018 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 A3L08_04160 1014ffa6fb050e8e21f85d6ab18d231f 148 ProSitePatterns PS00475 Ribosomal protein L15 signature. 112 142 - T 23-10-2018 IPR001196 Ribosomal protein L15, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_04160 1014ffa6fb050e8e21f85d6ab18d231f 148 Gene3D G3DSA:4.10.990.10 4 53 4.4E-10 T 23-10-2018 IPR027386 50S ribosomal protein L15, N-terminal A3L08_04160 1014ffa6fb050e8e21f85d6ab18d231f 148 SUPERFAMILY SSF52080 5 147 5.49E-33 T 23-10-2018 IPR036227 Ribosomal L18e/L15P superfamily A3L08_02685 14d397ed4b56b909bf7d1e16b4c62fd7 254 TIGRFAM TIGR00552 nadE: NAD+ synthetase 8 249 5.7E-85 T 23-10-2018 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 A3L08_02685 14d397ed4b56b909bf7d1e16b4c62fd7 254 Gene3D G3DSA:3.40.50.620 8 254 2.8E-94 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L08_02685 14d397ed4b56b909bf7d1e16b4c62fd7 254 Pfam PF02540 NAD synthase 10 249 3.7E-86 T 23-10-2018 IPR022310 NAD/GMP synthase A3L08_02685 14d397ed4b56b909bf7d1e16b4c62fd7 254 SUPERFAMILY SSF52402 4 249 4.85E-78 T 23-10-2018 A3L08_02685 14d397ed4b56b909bf7d1e16b4c62fd7 254 Hamap MF_00193 NH(3)-dependent NAD(+) synthetase [nadE]. 5 252 51.434 T 23-10-2018 IPR022926 NH(3)-dependent NAD(+) synthetase GO:0008795|GO:0009435 KEGG: 00760+6.3.1.5 A3L08_03605 37981289bb4f818de39f572bb09d599d 276 Hamap MF_01286 Digeranylgeranylglyceryl phosphate synthase. 3 275 22.754 T 23-10-2018 IPR023547 Digeranylgeranylglyceryl phosphate synthase GO:0000287|GO:0005886|GO:0008654|GO:0047295 KEGG: 00564+2.5.1.42|MetaCyc: PWY-6349 A3L08_03605 37981289bb4f818de39f572bb09d599d 276 Pfam PF01040 UbiA prenyltransferase family 23 256 1.7E-45 T 23-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 A3L08_03605 37981289bb4f818de39f572bb09d599d 276 Gene3D G3DSA:1.10.357.140 9 155 7.1E-17 T 23-10-2018 A3L08_03605 37981289bb4f818de39f572bb09d599d 276 Gene3D G3DSA:1.20.120.1780 158 276 1.3E-5 T 23-10-2018 A3L08_04090 de462c1f4b7c7fdf85d838f2260e7258 88 SUPERFAMILY SSF101744 2 87 4.19E-24 T 23-10-2018 IPR023534 Rof/RNase P-like Reactome: R-HSA-6784531 A3L08_04090 de462c1f4b7c7fdf85d838f2260e7258 88 SMART SM00538 1 88 9.4E-31 T 23-10-2018 IPR002730 Ribonuclease P/MRP, subunit p29 GO:0003723|GO:0004540|GO:0006396|GO:0030677 Reactome: R-HSA-6784531 A3L08_04090 de462c1f4b7c7fdf85d838f2260e7258 88 Gene3D G3DSA:2.30.30.210 1 88 3.4E-32 T 23-10-2018 IPR036980 Ribonuclease P/MRP, subunit p29 superfamily GO:0003723|GO:0004540|GO:0008033|GO:0030677 Reactome: R-HSA-6784531 A3L08_04090 de462c1f4b7c7fdf85d838f2260e7258 88 Pfam PF01868 Domain of unknown function UPF0086 5 84 3.5E-20 T 23-10-2018 IPR002730 Ribonuclease P/MRP, subunit p29 GO:0003723|GO:0004540|GO:0006396|GO:0030677 Reactome: R-HSA-6784531 A3L08_04090 de462c1f4b7c7fdf85d838f2260e7258 88 Hamap MF_00754 Ribonuclease P protein component 1 [rnp1]. 8 83 19.755 T 23-10-2018 IPR023538 Ribonuclease P protein component 1 GO:0001682|GO:0004526 A3L08_00020 151e3e1af7571fe9e682d296a5be8f14 119 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 9 115 2.9E-15 T 23-10-2018 IPR003477 mRNA interferase PemK-like GO:0003677 A3L08_00020 151e3e1af7571fe9e682d296a5be8f14 119 SUPERFAMILY SSF50118 8 118 6.1E-21 T 23-10-2018 A3L08_00020 151e3e1af7571fe9e682d296a5be8f14 119 Gene3D G3DSA:2.30.30.110 25 119 6.5E-21 T 23-10-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor A3L08_00400 25b1c733db63586dcdb6b24ee7c99f58 498 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 126 145 2.0E-8 T 23-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L08_00400 25b1c733db63586dcdb6b24ee7c99f58 498 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 308 327 2.0E-8 T 23-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L08_00400 25b1c733db63586dcdb6b24ee7c99f58 498 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 156 180 2.0E-8 T 23-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L08_00400 25b1c733db63586dcdb6b24ee7c99f58 498 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 225 249 2.0E-8 T 23-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L08_00400 25b1c733db63586dcdb6b24ee7c99f58 498 Pfam PF00361 Proton-conducting membrane transporter 120 398 1.1E-44 T 23-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L08_09615 83940638588f8981d525b9386e8bed45 147 Gene3D G3DSA:3.40.50.150 1 140 3.9E-23 T 23-10-2018 A3L08_09615 83940638588f8981d525b9386e8bed45 147 Pfam PF13847 Methyltransferase domain 1 117 3.9E-13 T 23-10-2018 IPR025714 Methyltransferase domain A3L08_09615 83940638588f8981d525b9386e8bed45 147 SUPERFAMILY SSF53335 1 125 1.53E-25 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L08_03085 317f95bb9fcf3b94d6c78b6ce9f91c4c 500 SUPERFAMILY SSF53649 2 293 1.46E-38 T 23-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 A3L08_03085 317f95bb9fcf3b94d6c78b6ce9f91c4c 500 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 5 427 1.2E-37 T 23-10-2018 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 A3L08_05425 b15a914f7e40776fc112f98768d176ac 473 Pfam PF01554 MatE 249 410 2.5E-26 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A3L08_05425 b15a914f7e40776fc112f98768d176ac 473 Pfam PF01554 MatE 28 188 8.4E-33 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A3L08_05425 b15a914f7e40776fc112f98768d176ac 473 PIRSF PIRSF006603 5 473 1.4E-155 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A3L08_05425 b15a914f7e40776fc112f98768d176ac 473 TIGRFAM TIGR00797 matE: MATE efflux family protein 28 416 5.4E-72 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A3L08_07580 58d609dcae3ad516704e18be7b09a4a0 576 PIRSF PIRSF029254 1 575 8.0E-195 T 23-10-2018 IPR012401 DNA-binding protein MutS2, archaea A3L08_07580 58d609dcae3ad516704e18be7b09a4a0 576 SUPERFAMILY SSF52540 347 552 7.19E-18 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_07580 58d609dcae3ad516704e18be7b09a4a0 576 Gene3D G3DSA:3.40.50.300 338 527 1.1E-21 T 23-10-2018 A3L08_07580 58d609dcae3ad516704e18be7b09a4a0 576 Hamap MF_00971 DNA-binding protein MutS2 [mutS2]. 3 573 25.183 T 23-10-2018 IPR012401 DNA-binding protein MutS2, archaea A3L08_07580 58d609dcae3ad516704e18be7b09a4a0 576 SMART SM00534 386 574 1.5E-26 T 23-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 A3L08_07580 58d609dcae3ad516704e18be7b09a4a0 576 Pfam PF00488 MutS domain V 389 470 5.0E-7 T 23-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 A3L08_05000 846658a4d5233ec479e5b5157926cf31 453 Gene3D G3DSA:3.40.640.10 81 351 1.8E-148 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A3L08_05000 846658a4d5233ec479e5b5157926cf31 453 Hamap MF_00712 Probable glycine dehydrogenase (decarboxylating) subunit 1 [gcvPA]. 3 447 47.323 T 23-10-2018 IPR023010 Probable glycine dehydrogenase (decarboxylating) subunit 1 GO:0004375|GO:0009116 KEGG: 00260+1.4.4.2 A3L08_05000 846658a4d5233ec479e5b5157926cf31 453 PIRSF PIRSF006815 3 448 1.4E-158 T 23-10-2018 IPR023010 Probable glycine dehydrogenase (decarboxylating) subunit 1 GO:0004375|GO:0009116 KEGG: 00260+1.4.4.2 A3L08_05000 846658a4d5233ec479e5b5157926cf31 453 Pfam PF02347 Glycine cleavage system P-protein 3 443 1.1E-122 T 23-10-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 A3L08_05000 846658a4d5233ec479e5b5157926cf31 453 SUPERFAMILY SSF53383 3 447 2.23E-102 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A3L08_05000 846658a4d5233ec479e5b5157926cf31 453 Gene3D G3DSA:3.90.1150.10 70 444 1.8E-148 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A3L08_04520 b802b069aa828f2bb2b630833164ec8f 502 SUPERFAMILY SSF161070 1 465 1.28E-90 T 23-10-2018 IPR037272 Sodium:neurotransmitter symporter superfamily GO:0005328 A3L08_04520 b802b069aa828f2bb2b630833164ec8f 502 Pfam PF00209 Sodium:neurotransmitter symporter family 2 116 9.3E-14 T 23-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 A3L08_04520 b802b069aa828f2bb2b630833164ec8f 502 Pfam PF00209 Sodium:neurotransmitter symporter family 129 457 3.3E-20 T 23-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 A3L08_04520 b802b069aa828f2bb2b630833164ec8f 502 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 25 44 7.4E-5 T 23-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 A3L08_04520 b802b069aa828f2bb2b630833164ec8f 502 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 321 340 7.4E-5 T 23-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 A3L08_08185 be9d53aba0191565e333856a49d76e0e 280 Gene3D G3DSA:3.40.50.720 1 151 3.0E-40 T 23-10-2018 A3L08_08185 be9d53aba0191565e333856a49d76e0e 280 Gene3D G3DSA:1.10.1040.10 152 279 1.8E-35 T 23-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A3L08_08185 be9d53aba0191565e333856a49d76e0e 280 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 155 274 9.5E-28 T 23-10-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 A3L08_08185 be9d53aba0191565e333856a49d76e0e 280 SUPERFAMILY SSF51735 2 152 3.52E-36 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L08_08185 be9d53aba0191565e333856a49d76e0e 280 PIRSF PIRSF000103 1 279 6.9E-76 T 23-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 A3L08_08185 be9d53aba0191565e333856a49d76e0e 280 SUPERFAMILY SSF48179 153 278 7.71E-34 T 23-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 A3L08_08185 be9d53aba0191565e333856a49d76e0e 280 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 2 149 4.2E-34 T 23-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 A3L08_06800 32be5fa7c611ae4de026859b24f0fc3d 138 SUPERFAMILY SSF88723 3 136 1.09E-23 T 23-10-2018 IPR029060 PIN-like domain superfamily A3L08_06800 32be5fa7c611ae4de026859b24f0fc3d 138 Pfam PF01850 PIN domain 3 133 7.9E-26 T 23-10-2018 IPR002716 PIN domain A3L08_06800 32be5fa7c611ae4de026859b24f0fc3d 138 Gene3D G3DSA:3.40.50.1010 2 138 1.4E-21 T 23-10-2018 A3L08_06800 32be5fa7c611ae4de026859b24f0fc3d 138 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 2 138 10.41 T 23-10-2018 IPR022907 VapC family GO:0004540 A3L08_06800 32be5fa7c611ae4de026859b24f0fc3d 138 SMART SM00670 1 130 8.4E-4 T 23-10-2018 IPR002716 PIN domain A3L08_09535 cc72e8f06d454a7fb9bfc7861c35b42f 162 SUPERFAMILY SSF49764 42 154 4.19E-33 T 23-10-2018 IPR008978 HSP20-like chaperone A3L08_09535 cc72e8f06d454a7fb9bfc7861c35b42f 162 Pfam PF00011 Hsp20/alpha crystallin family 58 154 1.1E-19 T 23-10-2018 IPR002068 Alpha crystallin/Hsp20 domain A3L08_09535 cc72e8f06d454a7fb9bfc7861c35b42f 162 Gene3D G3DSA:2.60.40.790 3 161 1.5E-33 T 23-10-2018 IPR008978 HSP20-like chaperone A3L08_00805 245f3996099a7ed27bee80f9d483d23f 260 Gene3D G3DSA:3.30.2010.10 49 132 4.7E-17 T 23-10-2018 A3L08_00805 245f3996099a7ed27bee80f9d483d23f 260 Pfam PF01435 Peptidase family M48 57 244 1.2E-20 T 23-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 A3L08_01715 ccabc724a0cfd0b5e8e2561fee38d73b 544 SUPERFAMILY SSF56300 315 543 1.04E-30 T 23-10-2018 A3L08_01715 ccabc724a0cfd0b5e8e2561fee38d73b 544 Pfam PF00149 Calcineurin-like phosphoesterase 315 492 1.1E-11 T 23-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 A3L08_01715 ccabc724a0cfd0b5e8e2561fee38d73b 544 Gene3D G3DSA:3.60.21.10 312 538 9.6E-17 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like A3L08_07060 db7453778286aec024ed841007ef0733 577 Pfam PF04473 Transglutaminase-like domain 297 414 2.2E-39 T 23-10-2018 IPR007562 Transglutaminase-like domain A3L08_07060 db7453778286aec024ed841007ef0733 577 Gene3D G3DSA:3.10.620.30 302 405 1.2E-9 T 23-10-2018 A3L08_07060 db7453778286aec024ed841007ef0733 577 SUPERFAMILY SSF54001 308 411 6.62E-8 T 23-10-2018 IPR038765 Papain-like cysteine peptidase superfamily A3L08_01855 608f86095777be4594d563cacdbe8f82 94 Gene3D G3DSA:3.30.2320.10 1 77 3.5E-23 T 23-10-2018 A3L08_01855 608f86095777be4594d563cacdbe8f82 94 Pfam PF08967 Domain of unknown function (DUF1884) 1 78 5.2E-25 T 23-10-2018 IPR014418 Uncharacterised conserved protein UCP004604 A3L08_01855 608f86095777be4594d563cacdbe8f82 94 SUPERFAMILY SSF111057 3 76 9.68E-25 T 23-10-2018 IPR036216 Hypothetical protein UCP004604 superfamily A3L08_01855 608f86095777be4594d563cacdbe8f82 94 ProDom PD029791 ORF 3'REGION GAP PF1875 PF0899 PH1831 B PHS036 6 76 2.0E-20 T 23-10-2018 IPR014418 Uncharacterised conserved protein UCP004604 A3L08_01855 608f86095777be4594d563cacdbe8f82 94 PIRSF PIRSF004604 1 93 9.8E-31 T 23-10-2018 IPR014418 Uncharacterised conserved protein UCP004604 A3L08_07800 2cee4465cc6f509b713c720bfeffffe8 267 SUPERFAMILY SSF143597 111 260 1.7E-30 T 23-10-2018 IPR036888 DNA integrity scanning protein, DisA, N-terminal domain superfamily A3L08_07800 2cee4465cc6f509b713c720bfeffffe8 267 PIRSF PIRSF019073 5 267 1.1E-76 T 23-10-2018 IPR014499 Diadenylate cyclase, DacZ-type A3L08_07800 2cee4465cc6f509b713c720bfeffffe8 267 Hamap MF_00840 Diadenylate cyclase [dacZ]. 8 266 34.4 T 23-10-2018 IPR014499 Diadenylate cyclase, DacZ-type A3L08_07800 2cee4465cc6f509b713c720bfeffffe8 267 Gene3D G3DSA:3.40.1700.10 178 265 1.8E-14 T 23-10-2018 IPR036888 DNA integrity scanning protein, DisA, N-terminal domain superfamily A3L08_07800 2cee4465cc6f509b713c720bfeffffe8 267 Pfam PF02457 DisA bacterial checkpoint controller nucleotide-binding 133 255 3.2E-22 T 23-10-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal A3L08_02795 2d30d5d127cd3244ff5178795cde2c24 134 Pfam PF03686 Uncharacterised protein family (UPF0146) 4 130 6.8E-29 T 23-10-2018 IPR005353 Uncharacterised protein family UPF0146 A3L08_02795 2d30d5d127cd3244ff5178795cde2c24 134 Hamap MF_00341 UPF0146 protein . 3 132 24.779 T 23-10-2018 IPR005353 Uncharacterised protein family UPF0146 A3L08_02795 2d30d5d127cd3244ff5178795cde2c24 134 ProDom PD021130 UPF0146 MJ0688 SIMILAR ARCHAEA UNCHARACTERIZED AF0739.1 MTH1000 PYRAB01940 PH0209 VNG2609C 19 112 2.0E-40 T 23-10-2018 IPR005353 Uncharacterised protein family UPF0146 A3L08_02795 2d30d5d127cd3244ff5178795cde2c24 134 Gene3D G3DSA:3.40.50.150 1 133 4.0E-22 T 23-10-2018 A3L08_05650 b62cefcf5364e131c67607dba2867def 305 Gene3D G3DSA:3.40.50.300 1 240 6.1E-59 T 23-10-2018 A3L08_05650 b62cefcf5364e131c67607dba2867def 305 SMART SM00382 26 227 8.2E-12 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L08_05650 b62cefcf5364e131c67607dba2867def 305 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L08_05650 b62cefcf5364e131c67607dba2867def 305 Pfam PF00005 ABC transporter 17 167 1.3E-29 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L08_05650 b62cefcf5364e131c67607dba2867def 305 SUPERFAMILY SSF52540 2 228 1.3E-55 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_08650 ff27eba47a0b8e340d69746fb7c98038 155 SUPERFAMILY SSF88697 6 146 4.05E-8 T 23-10-2018 IPR015947 PUA-like superfamily A3L08_07850 12e5189ca557525bebcf944343d1af70 226 SUPERFAMILY SSF53681 116 224 2.07E-25 T 23-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A3L08_07850 12e5189ca557525bebcf944343d1af70 226 TIGRFAM TIGR00035 asp_race: aspartate racemase 1 224 1.2E-52 T 23-10-2018 IPR004380 Aspartate racemase GO:0006520|GO:0016855 A3L08_07850 12e5189ca557525bebcf944343d1af70 226 Gene3D G3DSA:3.40.50.1860 3 215 4.9E-74 T 23-10-2018 A3L08_07850 12e5189ca557525bebcf944343d1af70 226 Pfam PF01177 Asp/Glu/Hydantoin racemase 7 220 1.8E-51 T 23-10-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A3L08_07850 12e5189ca557525bebcf944343d1af70 226 Gene3D G3DSA:3.40.50.1860 102 211 4.9E-74 T 23-10-2018 A3L08_07850 12e5189ca557525bebcf944343d1af70 226 SUPERFAMILY SSF53681 1 114 3.05E-28 T 23-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A3L08_03880 950e803a49bf26da9b505019ca3328a9 174 SUPERFAMILY SSF88697 3 143 1.57E-16 T 23-10-2018 IPR015947 PUA-like superfamily A3L08_03880 950e803a49bf26da9b505019ca3328a9 174 Pfam PF04266 ASCH domain 6 115 1.7E-8 T 23-10-2018 IPR007374 ASCH domain A3L08_03880 950e803a49bf26da9b505019ca3328a9 174 SMART SM01022 5 125 6.0E-8 T 23-10-2018 IPR007374 ASCH domain A3L08_00185 a505f5946d49acdf84fc51cf060eac3e 135 SUPERFAMILY SSF143870 12 127 8.5E-24 T 23-10-2018 IPR036504 CGI121/TPRKB superfamily Reactome: R-HSA-6782315 A3L08_00185 a505f5946d49acdf84fc51cf060eac3e 135 Gene3D G3DSA:3.30.2380.10 6 135 6.1E-43 T 23-10-2018 IPR036504 CGI121/TPRKB superfamily Reactome: R-HSA-6782315 A3L08_08385 25889aa1ed36680ce51372a6e526b642 332 SUPERFAMILY SSF53335 146 311 4.4E-31 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L08_08385 25889aa1ed36680ce51372a6e526b642 332 Gene3D G3DSA:3.30.2130.30 10 142 3.9E-6 T 23-10-2018 A3L08_08385 25889aa1ed36680ce51372a6e526b642 332 SMART SM00981 56 141 1.2E-8 T 23-10-2018 IPR004114 THUMP domain GO:0003723 A3L08_08385 25889aa1ed36680ce51372a6e526b642 332 Pfam PF02926 THUMP domain 41 133 1.1E-11 T 23-10-2018 IPR004114 THUMP domain GO:0003723 A3L08_08385 25889aa1ed36680ce51372a6e526b642 332 Gene3D G3DSA:3.40.50.150 153 332 1.5E-35 T 23-10-2018 A3L08_08385 25889aa1ed36680ce51372a6e526b642 332 SUPERFAMILY SSF143437 38 132 1.92E-9 T 23-10-2018 A3L08_08385 25889aa1ed36680ce51372a6e526b642 332 TIGRFAM TIGR01177 TIGR01177: putative methyltransferase, TIGR01177 family 3 328 4.2E-101 T 23-10-2018 IPR005885 tRNA guanine(10)-N2-dimethyltransferase GO:0004809|GO:0030488 A3L08_08385 25889aa1ed36680ce51372a6e526b642 332 Pfam PF01170 Putative RNA methylase family UPF0020 156 297 3.5E-26 T 23-10-2018 IPR000241 Putative RNA methylase domain A3L08_08385 25889aa1ed36680ce51372a6e526b642 332 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 251 257 - T 23-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 A3L08_08385 25889aa1ed36680ce51372a6e526b642 332 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 183 197 3.6E-8 T 23-10-2018 A3L08_08385 25889aa1ed36680ce51372a6e526b642 332 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 270 294 3.6E-8 T 23-10-2018 A3L08_08385 25889aa1ed36680ce51372a6e526b642 332 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 248 260 3.6E-8 T 23-10-2018 A3L08_06155 56c6c51896170ca0b4339100fa77910f 433 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 348 368 - T 23-10-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 A3L08_06155 56c6c51896170ca0b4339100fa77910f 433 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 23 430 1.2E-96 T 23-10-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 A3L08_06155 56c6c51896170ca0b4339100fa77910f 433 Pfam PF00860 Permease family 24 400 8.5E-93 T 23-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 A3L08_03580 6714b24c2cd7b0ba8e22421fc34662e7 56 Pfam PF03911 Sec61beta family 11 51 2.8E-16 T 23-10-2018 IPR016482 Protein transport protein SecG/Sec61-beta/Sbh Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A3L08_03580 6714b24c2cd7b0ba8e22421fc34662e7 56 Hamap MF_00751 Preprotein translocase subunit SecG [secG]. 1 51 15.035 T 23-10-2018 IPR023531 Preprotein translocase subunit SecG A3L08_07720 ebe1034952eadb1ac44d5997dd5811b7 422 Pfam PF13173 AAA domain 33 164 2.1E-32 T 23-10-2018 A3L08_07720 ebe1034952eadb1ac44d5997dd5811b7 422 SUPERFAMILY SSF52540 33 166 1.56E-19 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_07720 ebe1034952eadb1ac44d5997dd5811b7 422 Pfam PF13635 Domain of unknown function (DUF4143) 245 358 1.7E-10 T 23-10-2018 IPR025420 Domain of unknown function DUF4143 A3L08_06765 2f6468eebd0aa52e37ea7a323877b76b 382 Gene3D G3DSA:3.40.50.920 272 381 2.6E-25 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A3L08_06765 2f6468eebd0aa52e37ea7a323877b76b 382 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 22 257 4.2E-82 T 23-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 A3L08_06765 2f6468eebd0aa52e37ea7a323877b76b 382 Gene3D G3DSA:3.40.50.970 1 199 8.8E-85 T 23-10-2018 A3L08_06765 2f6468eebd0aa52e37ea7a323877b76b 382 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 282 376 5.7E-21 T 23-10-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II A3L08_06765 2f6468eebd0aa52e37ea7a323877b76b 382 SUPERFAMILY SSF52518 12 265 7.85E-72 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold A3L08_06765 2f6468eebd0aa52e37ea7a323877b76b 382 SUPERFAMILY SSF52922 274 378 7.33E-27 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A3L08_07825 47a09f35574f82b3613e714c7205982d 123 TIGRFAM TIGR00494 crcB: protein CrcB 8 121 1.3E-25 T 23-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 A3L08_07825 47a09f35574f82b3613e714c7205982d 123 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 6 122 19.152 T 23-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 A3L08_07825 47a09f35574f82b3613e714c7205982d 123 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 8 117 2.0E-24 T 23-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 A3L08_02845 b34e3bcb115804cea0f28e00fdf5d2c4 360 SUPERFAMILY SSF102114 27 207 9.81E-23 T 23-10-2018 A3L08_02845 b34e3bcb115804cea0f28e00fdf5d2c4 360 Gene3D G3DSA:3.20.20.70 24 286 7.0E-16 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L08_02845 b34e3bcb115804cea0f28e00fdf5d2c4 360 Pfam PF04055 Radical SAM superfamily 33 186 2.8E-11 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L08_08080 67bcd994649fbea8115fe4465e4efc3a 68 SUPERFAMILY SSF55008 1 66 1.01E-17 T 23-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 A3L08_08080 67bcd994649fbea8115fe4465e4efc3a 68 Gene3D G3DSA:3.30.70.100 1 67 2.1E-17 T 23-10-2018 A3L08_08080 67bcd994649fbea8115fe4465e4efc3a 68 Pfam PF00403 Heavy-metal-associated domain 5 64 8.9E-13 T 23-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 A3L08_03040 2bd7b8fa5ab50a67b2a894b6a34308c3 333 Gene3D G3DSA:3.40.50.720 4 294 2.0E-132 T 23-10-2018 A3L08_03040 2bd7b8fa5ab50a67b2a894b6a34308c3 333 SUPERFAMILY SSF51735 1 320 2.26E-95 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L08_03040 2bd7b8fa5ab50a67b2a894b6a34308c3 333 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 304 2.1E-83 T 23-10-2018 IPR016040 NAD(P)-binding domain A3L08_03040 2bd7b8fa5ab50a67b2a894b6a34308c3 333 Gene3D G3DSA:3.90.25.10 177 309 2.0E-132 T 23-10-2018 A3L08_03040 2bd7b8fa5ab50a67b2a894b6a34308c3 333 TIGRFAM TIGR01181 dTDP_gluc_dehyt: dTDP-glucose 4,6-dehydratase 2 318 8.8E-163 T 23-10-2018 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|KEGG: 00525+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 A3L08_00585 5f58dfca737634cf671057373dfcd8c8 308 Pfam PF01874 ATP:dephospho-CoA triphosphoribosyl transferase 8 286 5.2E-51 T 23-10-2018 IPR002736 Triphosphoribosyl-dephospho-CoA protein GO:0005524|GO:0016310|GO:0046917 MetaCyc: PWY-5796 A3L08_00585 5f58dfca737634cf671057373dfcd8c8 308 Gene3D G3DSA:1.10.4200.10 25 293 4.9E-61 T 23-10-2018 A3L08_05380 514c34167a3f2b045a360aded2e0d849 480 Pfam PF07885 Ion channel 400 479 3.0E-12 T 23-10-2018 IPR013099 Potassium channel domain A3L08_05380 514c34167a3f2b045a360aded2e0d849 480 Gene3D G3DSA:1.10.287.70 386 480 5.2E-13 T 23-10-2018 A3L08_05380 514c34167a3f2b045a360aded2e0d849 480 SUPERFAMILY SSF81324 394 479 3.4E-15 T 23-10-2018 A3L08_01280 74c22e3d45fa73778afb8b39925ca406 452 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 12 437 1.1E-53 T 23-10-2018 IPR002823 Protein of unknown function DUF112, transmembrane A3L08_01200 300aa7ac9c872e2623fc15026b9706e4 149 SUPERFAMILY SSF52402 2 149 2.18E-26 T 23-10-2018 A3L08_01200 300aa7ac9c872e2623fc15026b9706e4 149 Pfam PF00582 Universal stress protein family 2 149 9.9E-21 T 23-10-2018 IPR006016 UspA A3L08_01200 300aa7ac9c872e2623fc15026b9706e4 149 Gene3D G3DSA:3.40.50.620 1 149 4.8E-30 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L08_01535 ea730759280faf53d1f19823710f3d9c 589 Pfam PF13353 4Fe-4S single cluster domain 142 225 4.0E-6 T 23-10-2018 A3L08_01535 ea730759280faf53d1f19823710f3d9c 589 SUPERFAMILY SSF102114 127 395 2.49E-44 T 23-10-2018 A3L08_01535 ea730759280faf53d1f19823710f3d9c 589 Pfam PF04055 Radical SAM superfamily 142 301 1.7E-21 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L08_01535 ea730759280faf53d1f19823710f3d9c 589 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 144 155 - T 23-10-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A3L08_01535 ea730759280faf53d1f19823710f3d9c 589 Gene3D G3DSA:3.20.20.70 127 401 2.4E-33 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L08_06830 cedebdd49981278259c8ce7d89f2ef48 515 Pfam PF00005 ABC transporter 280 437 1.1E-16 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L08_06830 cedebdd49981278259c8ce7d89f2ef48 515 Pfam PF00005 ABC transporter 26 176 7.7E-27 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L08_06830 cedebdd49981278259c8ce7d89f2ef48 515 Gene3D G3DSA:3.40.50.300 259 505 1.0E-42 T 23-10-2018 A3L08_06830 cedebdd49981278259c8ce7d89f2ef48 515 SMART SM00382 35 224 1.7E-17 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L08_06830 cedebdd49981278259c8ce7d89f2ef48 515 SUPERFAMILY SSF52540 8 235 1.96E-60 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_06830 cedebdd49981278259c8ce7d89f2ef48 515 Gene3D G3DSA:3.40.50.300 2 244 1.2E-58 T 23-10-2018 A3L08_06830 cedebdd49981278259c8ce7d89f2ef48 515 ProSitePatterns PS00211 ABC transporters family signature. 410 424 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L08_06830 cedebdd49981278259c8ce7d89f2ef48 515 SUPERFAMILY SSF52540 261 498 1.66E-46 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_06530 89682bf636be0a6a79260b3ea0c3cad0 163 Pfam PF12838 4Fe-4S dicluster domain 29 78 1.2E-13 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L08_06530 89682bf636be0a6a79260b3ea0c3cad0 163 SUPERFAMILY SSF54862 7 108 5.02E-20 T 23-10-2018 A3L08_06530 89682bf636be0a6a79260b3ea0c3cad0 163 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 64 75 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L08_06530 89682bf636be0a6a79260b3ea0c3cad0 163 Gene3D G3DSA:3.30.70.3270 7 126 8.7E-21 T 23-10-2018 A3L08_04110 da0fd657ec5a5e636034ba27cfcc5042 243 Gene3D G3DSA:3.10.290.40 1 118 9.7E-50 T 23-10-2018 A3L08_04110 da0fd657ec5a5e636034ba27cfcc5042 243 Pfam PF00900 Ribosomal family S4e 96 173 6.5E-22 T 23-10-2018 IPR013845 Ribosomal protein S4e, central region Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_04110 da0fd657ec5a5e636034ba27cfcc5042 243 Pfam PF08071 RS4NT (NUC023) domain 4 39 1.9E-16 T 23-10-2018 IPR013843 Ribosomal protein S4e, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_04110 da0fd657ec5a5e636034ba27cfcc5042 243 SMART SM00363 44 107 9.8E-10 T 23-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_04110 da0fd657ec5a5e636034ba27cfcc5042 243 ProSitePatterns PS00528 Ribosomal protein S4e signature. 9 23 - T 23-10-2018 IPR018199 Ribosomal protein S4e, N-terminal, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_04110 da0fd657ec5a5e636034ba27cfcc5042 243 PIRSF PIRSF002116 2 243 8.7E-101 T 23-10-2018 IPR000876 Ribosomal protein S4e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_04110 da0fd657ec5a5e636034ba27cfcc5042 243 ProDom PD002667 RIBOSOMAL RIBONUCLEOPROTEIN RNA-BINDING 40S S4 S4 S4E 30S ISOFORM X 88 182 5.0E-42 T 23-10-2018 IPR013845 Ribosomal protein S4e, central region Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_04110 da0fd657ec5a5e636034ba27cfcc5042 243 SUPERFAMILY SSF55174 53 104 5.89E-8 T 23-10-2018 A3L08_04110 da0fd657ec5a5e636034ba27cfcc5042 243 Gene3D G3DSA:2.30.30.30 179 243 1.2E-18 T 23-10-2018 IPR014722 Ribosomal protein L2, domain 2 A3L08_04110 da0fd657ec5a5e636034ba27cfcc5042 243 Pfam PF01479 S4 domain 45 91 2.7E-13 T 23-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_04110 da0fd657ec5a5e636034ba27cfcc5042 243 Hamap MF_00485 30S ribosomal protein S4e [rps4e]. 8 242 42.873 T 23-10-2018 IPR000876 Ribosomal protein S4e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_04110 da0fd657ec5a5e636034ba27cfcc5042 243 Gene3D G3DSA:2.40.50.740 123 177 1.1E-15 T 23-10-2018 IPR038237 Ribosomal protein S4e, central domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_02720 7c84cfb0cb8ede8bba1f5fdde81d7766 282 Pfam PF00892 EamA-like transporter family 150 276 1.1E-18 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A3L08_02720 7c84cfb0cb8ede8bba1f5fdde81d7766 282 Pfam PF00892 EamA-like transporter family 7 137 1.4E-16 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A3L08_02720 7c84cfb0cb8ede8bba1f5fdde81d7766 282 SUPERFAMILY SSF103481 43 141 8.11E-14 T 23-10-2018 A3L08_02720 7c84cfb0cb8ede8bba1f5fdde81d7766 282 SUPERFAMILY SSF103481 184 280 5.49E-13 T 23-10-2018 A3L08_07200 2106d9383eb25c563c5d14a2e3c4fb3d 378 Gene3D G3DSA:3.40.50.150 1 317 2.4E-101 T 23-10-2018 A3L08_07200 2106d9383eb25c563c5d14a2e3c4fb3d 378 SUPERFAMILY SSF53335 3 375 5.43E-103 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L08_07200 2106d9383eb25c563c5d14a2e3c4fb3d 378 TIGRFAM TIGR00308 TRM1: N2,N2-dimethylguanosine tRNA methyltransferase 6 375 3.2E-94 T 23-10-2018 IPR002905 tRNA methyltransferase, Trm1 GO:0003723|GO:0004809|GO:0008033 MetaCyc: PWY-6829 A3L08_07200 2106d9383eb25c563c5d14a2e3c4fb3d 378 Hamap MF_00290 tRNA (guanine(26)-N(2))-dimethyltransferase [trm1]. 4 376 42.782 T 23-10-2018 IPR022923 tRNA (guanine(26)-N(2))-dimethyltransferase, archaeal and bacterial GO:0004809 MetaCyc: PWY-6829 A3L08_07200 2106d9383eb25c563c5d14a2e3c4fb3d 378 Gene3D G3DSA:3.30.56.70 318 377 1.3E-19 T 23-10-2018 A3L08_07200 2106d9383eb25c563c5d14a2e3c4fb3d 378 Pfam PF02005 N2,N2-dimethylguanosine tRNA methyltransferase 10 375 4.8E-113 T 23-10-2018 IPR002905 tRNA methyltransferase, Trm1 GO:0003723|GO:0004809|GO:0008033 MetaCyc: PWY-6829 A3L08_07130 b3a2df4644e621ba6b471840fb623ac4 275 SUPERFAMILY SSF100950 10 272 4.96E-67 T 23-10-2018 IPR037171 NagB/RpiA transferase-like A3L08_07130 b3a2df4644e621ba6b471840fb623ac4 275 Gene3D G3DSA:1.20.120.420 1 95 4.5E-32 T 23-10-2018 IPR027363 Methylthioribose-1-phosphate isomerase, N-terminal KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 A3L08_07130 b3a2df4644e621ba6b471840fb623ac4 275 Pfam PF01008 Initiation factor 2 subunit family 19 271 2.2E-49 T 23-10-2018 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 A3L08_07130 b3a2df4644e621ba6b471840fb623ac4 275 Gene3D G3DSA:3.40.50.10470 96 275 1.8E-60 T 23-10-2018 A3L08_03810 b4551af8ae6a33743ec5fce45a1f29a8 227 Gene3D G3DSA:3.30.420.440 1 227 1.2E-105 T 23-10-2018 A3L08_03810 b4551af8ae6a33743ec5fce45a1f29a8 227 Pfam PF13680 Protein of unknown function (DUF4152) 1 224 1.8E-131 T 23-10-2018 IPR025206 Protein of unknown function DUF4152 A3L08_01585 f352e3698d1193a82e75d3983087a1f2 175 SUPERFAMILY SSF52540 4 175 5.52E-57 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_01585 f352e3698d1193a82e75d3983087a1f2 175 Pfam PF02572 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP 8 175 1.3E-61 T 23-10-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17 A3L08_01585 f352e3698d1193a82e75d3983087a1f2 175 PIRSF PIRSF015617 1 175 2.2E-62 T 23-10-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17 A3L08_01585 f352e3698d1193a82e75d3983087a1f2 175 Gene3D G3DSA:3.40.50.300 1 175 1.2E-65 T 23-10-2018 A3L08_01585 f352e3698d1193a82e75d3983087a1f2 175 TIGRFAM TIGR00708 cobA: cob(I)yrinic acid a,c-diamide adenosyltransferase 3 175 8.3E-70 T 23-10-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17 A3L08_07570 0e372125ca7ae1666f16d7621287e78c 153 Gene3D G3DSA:3.30.70.640 1 153 2.0E-68 T 23-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A3L08_07570 0e372125ca7ae1666f16d7621287e78c 153 Hamap MF_01224_A Cyclic pyranopterin monophosphate synthase [moaC]. 8 153 38.932 T 23-10-2018 IPR023047 Probable cyclic pyranopterin monophosphate synthase accessory protein, archaea KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823 A3L08_07570 0e372125ca7ae1666f16d7621287e78c 153 SUPERFAMILY SSF55040 11 153 3.66E-51 T 23-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A3L08_07570 0e372125ca7ae1666f16d7621287e78c 153 TIGRFAM TIGR00581 moaC: molybdenum cofactor biosynthesis protein C 3 140 2.0E-54 T 23-10-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A3L08_07570 0e372125ca7ae1666f16d7621287e78c 153 Pfam PF01967 MoaC family 13 153 3.4E-52 T 23-10-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A3L08_07650 4c32b812d4f75897a14883f5e5e11a28 396 SMART SM00852 186 317 1.5E-30 T 23-10-2018 IPR001453 MoaB/Mog domain A3L08_07650 4c32b812d4f75897a14883f5e5e11a28 396 SUPERFAMILY SSF53218 181 321 5.63E-34 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily A3L08_07650 4c32b812d4f75897a14883f5e5e11a28 396 Pfam PF03454 MoeA C-terminal region (domain IV) 329 395 3.3E-17 T 23-10-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A3L08_07650 4c32b812d4f75897a14883f5e5e11a28 396 SUPERFAMILY SSF63867 327 396 2.22E-19 T 23-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A3L08_07650 4c32b812d4f75897a14883f5e5e11a28 396 Gene3D G3DSA:3.90.105.10 27 181 5.6E-106 T 23-10-2018 A3L08_07650 4c32b812d4f75897a14883f5e5e11a28 396 Gene3D G3DSA:2.170.190.11 50 148 5.6E-106 T 23-10-2018 A3L08_07650 4c32b812d4f75897a14883f5e5e11a28 396 Pfam PF03453 MoeA N-terminal region (domain I and II) 9 173 6.8E-47 T 23-10-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A3L08_07650 4c32b812d4f75897a14883f5e5e11a28 396 Pfam PF00994 Probable molybdopterin binding domain 186 315 4.6E-19 T 23-10-2018 IPR001453 MoaB/Mog domain A3L08_07650 4c32b812d4f75897a14883f5e5e11a28 396 Gene3D G3DSA:2.40.340.10 320 396 2.5E-27 T 23-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A3L08_07650 4c32b812d4f75897a14883f5e5e11a28 396 SUPERFAMILY SSF63882 7 182 1.11E-57 T 23-10-2018 IPR036135 MoeA, N-terminal and linker domain superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A3L08_07650 4c32b812d4f75897a14883f5e5e11a28 396 Gene3D G3DSA:3.40.980.10 19 314 5.6E-106 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily A3L08_08835 8d428056fc5eb0684a709eaa300e1abf 308 ProSitePatterns PS01270 Band 7 protein family signature. 134 162 - T 23-10-2018 IPR018080 Band 7/stomatin-like, conserved site A3L08_08835 8d428056fc5eb0684a709eaa300e1abf 308 Pfam PF01145 SPFH domain / Band 7 family 25 194 5.4E-41 T 23-10-2018 IPR001107 Band 7 domain A3L08_08835 8d428056fc5eb0684a709eaa300e1abf 308 Gene3D G3DSA:3.30.479.30 49 180 2.2E-51 T 23-10-2018 A3L08_08835 8d428056fc5eb0684a709eaa300e1abf 308 SMART SM00244 21 178 2.0E-71 T 23-10-2018 IPR001107 Band 7 domain A3L08_08835 8d428056fc5eb0684a709eaa300e1abf 308 PRINTS PR00721 Stomatin signature 173 194 9.7E-35 T 23-10-2018 IPR001972 Stomatin family GO:0016020 A3L08_08835 8d428056fc5eb0684a709eaa300e1abf 308 PRINTS PR00721 Stomatin signature 75 96 9.7E-35 T 23-10-2018 IPR001972 Stomatin family GO:0016020 A3L08_08835 8d428056fc5eb0684a709eaa300e1abf 308 PRINTS PR00721 Stomatin signature 154 172 9.7E-35 T 23-10-2018 IPR001972 Stomatin family GO:0016020 A3L08_08835 8d428056fc5eb0684a709eaa300e1abf 308 PRINTS PR00721 Stomatin signature 110 127 9.7E-35 T 23-10-2018 IPR001972 Stomatin family GO:0016020 A3L08_08835 8d428056fc5eb0684a709eaa300e1abf 308 PRINTS PR00721 Stomatin signature 28 50 9.7E-35 T 23-10-2018 IPR001972 Stomatin family GO:0016020 A3L08_08835 8d428056fc5eb0684a709eaa300e1abf 308 PRINTS PR00721 Stomatin signature 130 153 9.7E-35 T 23-10-2018 IPR001972 Stomatin family GO:0016020 A3L08_08835 8d428056fc5eb0684a709eaa300e1abf 308 SUPERFAMILY SSF117892 52 185 1.7E-46 T 23-10-2018 IPR036013 Band 7/SPFH domain superfamily A3L08_04500 49654e8e4e08a40ec6c18de9e8fa80da 650 Pfam PF05833 Fibronectin-binding protein A N-terminus (FbpA) 7 442 1.6E-82 T 23-10-2018 A3L08_04500 49654e8e4e08a40ec6c18de9e8fa80da 650 Pfam PF05670 Domain of unknown function (DUF814) 455 553 1.8E-25 T 23-10-2018 IPR008532 Domain of unknown function DUF814 A3L08_04500 49654e8e4e08a40ec6c18de9e8fa80da 650 Gene3D G3DSA:2.30.310.10 5 150 2.0E-32 T 23-10-2018 A3L08_01675 d225c20e31ccc74db6a4e76c51241901 215 SUPERFAMILY SSF56112 7 154 2.45E-14 T 23-10-2018 IPR011009 Protein kinase-like domain superfamily A3L08_01885 15faf02970934e6755b7125d2eb10880 1372 SUPERFAMILY SSF82866 1125 1361 6.93E-22 T 23-10-2018 A3L08_01885 15faf02970934e6755b7125d2eb10880 1372 Gene3D G3DSA:1.20.1640.10 799 982 7.1E-7 T 23-10-2018 A3L08_01885 15faf02970934e6755b7125d2eb10880 1372 SUPERFAMILY SSF82866 750 982 1.44E-25 T 23-10-2018 A3L08_01885 15faf02970934e6755b7125d2eb10880 1372 Pfam PF03176 MMPL family 1045 1361 5.2E-30 T 23-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 A3L08_01885 15faf02970934e6755b7125d2eb10880 1372 Pfam PF03176 MMPL family 742 989 3.1E-37 T 23-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 A3L08_05340 68f7e5bd6203ab02a449731c15557d07 74 Pfam PF01455 HupF/HypC family 1 65 1.8E-30 T 23-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC A3L08_05340 68f7e5bd6203ab02a449731c15557d07 74 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 17 33 1.4E-14 T 23-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC A3L08_05340 68f7e5bd6203ab02a449731c15557d07 74 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 56 68 1.4E-14 T 23-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC A3L08_05340 68f7e5bd6203ab02a449731c15557d07 74 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 2 9 1.4E-14 T 23-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC A3L08_05340 68f7e5bd6203ab02a449731c15557d07 74 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 38 54 1.4E-14 T 23-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC A3L08_05340 68f7e5bd6203ab02a449731c15557d07 74 SUPERFAMILY SSF159127 1 73 1.96E-27 T 23-10-2018 IPR037254 HupF/HypC superfamily A3L08_05340 68f7e5bd6203ab02a449731c15557d07 74 Gene3D G3DSA:2.40.50.970 1 74 1.3E-34 T 23-10-2018 IPR037254 HupF/HypC superfamily A3L08_05340 68f7e5bd6203ab02a449731c15557d07 74 ProSitePatterns PS01097 Hydrogenases expression/synthesis hupF/hypC family signature. 1 9 - T 23-10-2018 IPR019812 Hydrogenase assembly chaperone, conserved site A3L08_05340 68f7e5bd6203ab02a449731c15557d07 74 TIGRFAM TIGR00074 hypC_hupF: hydrogenase assembly chaperone HypC/HupF 1 72 3.7E-28 T 23-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC A3L08_06110 b51efb1b4edc8cc07bbf54ad02c140ad 155 SUPERFAMILY SSF49777 7 154 1.83E-45 T 23-10-2018 IPR036610 PEBP-like superfamily A3L08_06110 b51efb1b4edc8cc07bbf54ad02c140ad 155 TIGRFAM TIGR00481 TIGR00481: Raf kinase inhibitor-like protein, YbhB/YbcL family 20 152 1.2E-43 T 23-10-2018 IPR005247 YbhB/YbcL A3L08_06110 b51efb1b4edc8cc07bbf54ad02c140ad 155 Pfam PF01161 Phosphatidylethanolamine-binding protein 15 152 1.9E-34 T 23-10-2018 IPR008914 Phosphatidylethanolamine-binding protein A3L08_06110 b51efb1b4edc8cc07bbf54ad02c140ad 155 Gene3D G3DSA:3.90.280.10 5 155 1.7E-50 T 23-10-2018 IPR036610 PEBP-like superfamily A3L08_09275 1d4fc9948de1eb8b42c16c980e80bde7 202 SUPERFAMILY SSF55469 1 201 8.77E-47 T 23-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A3L08_09275 1d4fc9948de1eb8b42c16c980e80bde7 202 Pfam PF00881 Nitroreductase family 7 181 6.5E-35 T 23-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 A3L08_09275 1d4fc9948de1eb8b42c16c980e80bde7 202 Gene3D G3DSA:3.40.109.10 1 201 4.3E-49 T 23-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A3L08_00570 6ba2dacb0c1ae94c1ac9801a5773bbfe 136 Gene3D G3DSA:3.30.300.20 5 136 1.3E-34 T 23-10-2018 IPR015946 K homology domain-like, alpha/beta A3L08_00570 6ba2dacb0c1ae94c1ac9801a5773bbfe 136 SUPERFAMILY SSF82784 8 133 4.71E-32 T 23-10-2018 IPR036102 OsmC/Ohr superfamily A3L08_00570 6ba2dacb0c1ae94c1ac9801a5773bbfe 136 Pfam PF02566 OsmC-like protein 32 119 4.2E-16 T 23-10-2018 IPR003718 OsmC/Ohr family A3L08_09150 39bf01ec5347b29a16f3b78c33951063 291 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 111 246 8.7E-14 T 23-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 A3L08_09150 39bf01ec5347b29a16f3b78c33951063 291 SUPERFAMILY SSF48150 93 271 1.05E-34 T 23-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 A3L08_09150 39bf01ec5347b29a16f3b78c33951063 291 Gene3D G3DSA:1.10.340.30 104 218 4.2E-34 T 23-10-2018 A3L08_09150 39bf01ec5347b29a16f3b78c33951063 291 SMART SM00478 114 272 1.7E-20 T 23-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 A3L08_09150 39bf01ec5347b29a16f3b78c33951063 291 Gene3D G3DSA:1.10.1670.40 84 267 4.2E-34 T 23-10-2018 A3L08_01575 d263a44c5b681d117e2296ae78d235f8 192 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 8 182 2.9E-46 T 23-10-2018 IPR001303 Class II aldolase/adducin N-terminal A3L08_01575 d263a44c5b681d117e2296ae78d235f8 192 Gene3D G3DSA:3.40.225.10 2 192 3.2E-59 T 23-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily A3L08_01575 d263a44c5b681d117e2296ae78d235f8 192 SUPERFAMILY SSF53639 5 186 6.67E-53 T 23-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily A3L08_01575 d263a44c5b681d117e2296ae78d235f8 192 SMART SM01007 7 183 1.5E-57 T 23-10-2018 IPR001303 Class II aldolase/adducin N-terminal A3L08_00360 9748f93ecfb094a9944d41b82e27be83 134 Gene3D G3DSA:2.40.50.100 2 132 2.7E-52 T 23-10-2018 A3L08_00360 9748f93ecfb094a9944d41b82e27be83 134 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 11 132 1.9E-46 T 23-10-2018 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 A3L08_00360 9748f93ecfb094a9944d41b82e27be83 134 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 54 83 - T 23-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 A3L08_00360 9748f93ecfb094a9944d41b82e27be83 134 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 10 132 41.274 T 23-10-2018 IPR002930 Glycine cleavage system H-protein GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 A3L08_00360 9748f93ecfb094a9944d41b82e27be83 134 Pfam PF01597 Glycine cleavage H-protein 13 133 7.5E-50 T 23-10-2018 IPR033753 Glycine cleavage system H-protein/Simiate A3L08_00360 9748f93ecfb094a9944d41b82e27be83 134 SUPERFAMILY SSF51230 10 133 4.97E-43 T 23-10-2018 IPR011053 Single hybrid motif A3L08_05065 dd31bbc8aa72716b0147ca04c1bf305e 215 Pfam PF00177 Ribosomal protein S7p/S5e 58 215 9.3E-38 T 23-10-2018 IPR023798 Ribosomal protein S7 domain A3L08_05065 dd31bbc8aa72716b0147ca04c1bf305e 215 TIGRFAM TIGR01028 uS7_euk_arch: ribosomal protein uS7 16 215 1.0E-88 T 23-10-2018 IPR005716 Ribosomal protein S5/S7, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_05065 dd31bbc8aa72716b0147ca04c1bf305e 215 Hamap MF_00480_A 30S ribosomal protein S7 [rpsG]. 15 215 38.012 T 23-10-2018 IPR026018 Ribosomal protein S7, archaeal A3L08_05065 dd31bbc8aa72716b0147ca04c1bf305e 215 Gene3D G3DSA:1.10.455.10 16 215 3.8E-79 T 23-10-2018 IPR036823 Ribosomal protein S7 domain superfamily A3L08_05065 dd31bbc8aa72716b0147ca04c1bf305e 215 SUPERFAMILY SSF47973 16 215 1.83E-62 T 23-10-2018 IPR036823 Ribosomal protein S7 domain superfamily A3L08_05065 dd31bbc8aa72716b0147ca04c1bf305e 215 PIRSF PIRSF002122 1 215 3.3E-49 T 23-10-2018 IPR000235 Ribosomal protein S5/S7 GO:0006412 A3L08_04270 9cc0042d3c63bcbaac3c8ef58af7553e 341 SMART SM01192 124 340 3.5E-13 T 23-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L08_04270 9cc0042d3c63bcbaac3c8ef58af7553e 341 SUPERFAMILY SSF54826 1 123 5.48E-30 T 23-10-2018 A3L08_04270 9cc0042d3c63bcbaac3c8ef58af7553e 341 SUPERFAMILY SSF51604 125 337 6.4E-29 T 23-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily A3L08_04270 9cc0042d3c63bcbaac3c8ef58af7553e 341 Gene3D G3DSA:3.20.20.120 221 339 8.2E-13 T 23-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily A3L08_04270 9cc0042d3c63bcbaac3c8ef58af7553e 341 Pfam PF03952 Enolase, N-terminal domain 38 119 4.6E-22 T 23-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L08_04270 9cc0042d3c63bcbaac3c8ef58af7553e 341 Pfam PF00113 Enolase, C-terminal TIM barrel domain 247 334 1.5E-8 T 23-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L08_04270 9cc0042d3c63bcbaac3c8ef58af7553e 341 Gene3D G3DSA:3.30.390.10 1 111 1.4E-20 T 23-10-2018 IPR029017 Enolase-like, N-terminal A3L08_04270 9cc0042d3c63bcbaac3c8ef58af7553e 341 PRINTS PR00148 Enolase signature 92 108 2.5E-5 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L08_04270 9cc0042d3c63bcbaac3c8ef58af7553e 341 PRINTS PR00148 Enolase signature 316 330 2.5E-5 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L08_04270 9cc0042d3c63bcbaac3c8ef58af7553e 341 SMART SM01193 4 119 1.0E-33 T 23-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A3L08_08645 1f059c4b67e2727bb5a2ada95bfd6a9a 350 SUPERFAMILY SSF53187 8 341 1.06E-40 T 23-10-2018 A3L08_08645 1f059c4b67e2727bb5a2ada95bfd6a9a 350 Gene3D G3DSA:3.40.630.10 15 336 2.4E-62 T 23-10-2018 A3L08_08645 1f059c4b67e2727bb5a2ada95bfd6a9a 350 SUPERFAMILY SSF55031 156 259 4.64E-10 T 23-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain A3L08_08645 1f059c4b67e2727bb5a2ada95bfd6a9a 350 Pfam PF01546 Peptidase family M20/M25/M40 64 341 5.1E-26 T 23-10-2018 IPR002933 Peptidase M20 GO:0016787 A3L08_08645 1f059c4b67e2727bb5a2ada95bfd6a9a 350 Gene3D G3DSA:3.30.70.360 155 264 2.4E-62 T 23-10-2018 A3L08_08645 1f059c4b67e2727bb5a2ada95bfd6a9a 350 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 87 124 - T 23-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 A3L08_08645 1f059c4b67e2727bb5a2ada95bfd6a9a 350 Pfam PF07687 Peptidase dimerisation domain 152 257 2.2E-8 T 23-10-2018 IPR011650 Peptidase M20, dimerisation domain A3L08_08925 cee51f1cf96c52aca06f0e70fb9199cb 244 Pfam PF03099 Biotin/lipoate A/B protein ligase family 82 201 1.0E-10 T 23-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 A3L08_08925 cee51f1cf96c52aca06f0e70fb9199cb 244 Gene3D G3DSA:3.30.930.10 71 242 1.9E-36 T 23-10-2018 A3L08_08925 cee51f1cf96c52aca06f0e70fb9199cb 244 Pfam PF08279 HTH domain 9 58 4.6E-13 T 23-10-2018 IPR013196 Helix-turn-helix, type 11 A3L08_08925 cee51f1cf96c52aca06f0e70fb9199cb 244 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 79 221 4.2E-32 T 23-10-2018 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A3L08_08925 cee51f1cf96c52aca06f0e70fb9199cb 244 SUPERFAMILY SSF46785 4 61 4.68E-10 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L08_08925 cee51f1cf96c52aca06f0e70fb9199cb 244 SUPERFAMILY SSF55681 69 230 2.77E-35 T 23-10-2018 A3L08_08925 cee51f1cf96c52aca06f0e70fb9199cb 244 Gene3D G3DSA:1.10.10.10 2 62 4.3E-17 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L08_03370 8d2bbc1e05f0e677b7986a46a45a59bb 178 Pfam PF04019 Protein of unknown function (DUF359) 51 172 1.1E-38 T 23-10-2018 IPR007164 Protein of unknown function DUF359 A3L08_03370 8d2bbc1e05f0e677b7986a46a45a59bb 178 PIRSF PIRSF006533 1 176 1.1E-53 T 23-10-2018 IPR007164 Protein of unknown function DUF359 A3L08_03370 8d2bbc1e05f0e677b7986a46a45a59bb 178 Hamap MF_00590 UPF0218 protein . 7 174 29.198 T 23-10-2018 IPR007164 Protein of unknown function DUF359 A3L08_00665 1a5b303d1eab61854961bd205ec2c231 225 Gene3D G3DSA:3.40.1160.10 1 225 2.2E-60 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily A3L08_00665 1a5b303d1eab61854961bd205ec2c231 225 Hamap MF_01220_A Uridylate kinase [pyrH]. 1 225 35.242 T 23-10-2018 IPR011818 Uridylate kinase, archaeal/spirochete, putative GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 A3L08_00665 1a5b303d1eab61854961bd205ec2c231 225 SUPERFAMILY SSF53633 1 224 3.8E-51 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily A3L08_00665 1a5b303d1eab61854961bd205ec2c231 225 Pfam PF00696 Amino acid kinase family 1 202 3.9E-34 T 23-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 A3L08_00665 1a5b303d1eab61854961bd205ec2c231 225 TIGRFAM TIGR02076 pyrH_arch: putative uridylate kinase 3 224 7.2E-87 T 23-10-2018 IPR011818 Uridylate kinase, archaeal/spirochete, putative GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 A3L08_00665 1a5b303d1eab61854961bd205ec2c231 225 PIRSF PIRSF005650 1 225 2.1E-59 T 23-10-2018 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 A3L08_01860 9357bdf10612b4b048ddf09310af6bf2 223 PIRSF PIRSF001357 1 223 1.1E-91 T 23-10-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 A3L08_01860 9357bdf10612b4b048ddf09310af6bf2 223 Pfam PF01791 DeoC/LacD family aldolase 10 217 5.7E-23 T 23-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 A3L08_01860 9357bdf10612b4b048ddf09310af6bf2 223 SMART SM01133 5 220 9.0E-118 T 23-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 A3L08_01860 9357bdf10612b4b048ddf09310af6bf2 223 TIGRFAM TIGR00126 deoC: deoxyribose-phosphate aldolase 6 218 5.5E-92 T 23-10-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 A3L08_01860 9357bdf10612b4b048ddf09310af6bf2 223 SUPERFAMILY SSF51569 2 220 2.41E-94 T 23-10-2018 A3L08_01860 9357bdf10612b4b048ddf09310af6bf2 223 Gene3D G3DSA:3.20.20.70 1 223 3.2E-108 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L08_01860 9357bdf10612b4b048ddf09310af6bf2 223 Hamap MF_00114 Deoxyribose-phosphate aldolase [deoC]. 4 222 39.872 T 23-10-2018 IPR028581 Deoxyribose-phosphate aldolase type I GO:0004139 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180 A3L08_01880 48f799ddf802536242c175e720fa315c 165 Pfam PF03551 Transcriptional regulator PadR-like family 19 92 1.6E-15 T 23-10-2018 IPR005149 Transcription regulator PadR, N-terminal A3L08_01880 48f799ddf802536242c175e720fa315c 165 SUPERFAMILY SSF46785 7 99 6.42E-22 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L08_01880 48f799ddf802536242c175e720fa315c 165 Gene3D G3DSA:1.10.10.10 6 118 8.3E-20 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L08_02575 72534c5c38e77175b56d10b2105d27d1 668 Gene3D G3DSA:1.20.1460.20 47 290 5.6E-22 T 23-10-2018 A3L08_02575 72534c5c38e77175b56d10b2105d27d1 668 Gene3D G3DSA:3.30.70.2750 149 224 5.6E-22 T 23-10-2018 A3L08_02575 72534c5c38e77175b56d10b2105d27d1 668 Pfam PF01496 V-type ATPase 116kDa subunit family 80 447 3.8E-24 T 23-10-2018 IPR002490 V-type ATPase, V0 complex, 116kDa subunit family GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A3L08_02575 72534c5c38e77175b56d10b2105d27d1 668 Pfam PF01496 V-type ATPase 116kDa subunit family 560 653 1.4E-12 T 23-10-2018 IPR002490 V-type ATPase, V0 complex, 116kDa subunit family GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A3L08_02575 72534c5c38e77175b56d10b2105d27d1 668 Gene3D G3DSA:3.30.70.2170 7 310 5.6E-22 T 23-10-2018 A3L08_03380 9dd066096f63407ae96311d1f26555f4 186 SUPERFAMILY SSF50249 80 179 5.74E-25 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L08_03380 9dd066096f63407ae96311d1f26555f4 186 Gene3D G3DSA:2.40.50.140 82 186 7.4E-32 T 23-10-2018 A3L08_03380 9dd066096f63407ae96311d1f26555f4 186 Pfam PF00575 S1 RNA binding domain 78 154 5.7E-16 T 23-10-2018 IPR003029 S1 domain GO:0003676 A3L08_03380 9dd066096f63407ae96311d1f26555f4 186 Pfam PF03876 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 8 77 8.2E-19 T 23-10-2018 IPR005576 RNA polymerase Rpb7, N-terminal GO:0003899|GO:0006351 A3L08_03380 9dd066096f63407ae96311d1f26555f4 186 TIGRFAM TIGR00448 rpoE: DNA-directed RNA polymerase 1 179 2.1E-68 T 23-10-2018 IPR004519 DNA-directed RNA polymerase, subunit E/RPC8 GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-1834949|Reactome: R-HSA-73780|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071 A3L08_03380 9dd066096f63407ae96311d1f26555f4 186 Gene3D G3DSA:3.30.1490.120 1 81 2.6E-32 T 23-10-2018 IPR036898 RNA polymerase Rpb7-like, N-terminal domain superfamily GO:0003899|GO:0006351 A3L08_03380 9dd066096f63407ae96311d1f26555f4 186 SUPERFAMILY SSF88798 1 78 1.02E-21 T 23-10-2018 IPR036898 RNA polymerase Rpb7-like, N-terminal domain superfamily GO:0003899|GO:0006351 A3L08_03380 9dd066096f63407ae96311d1f26555f4 186 SMART SM00316 80 166 4.5E-18 T 23-10-2018 IPR022967 RNA-binding domain, S1 A3L08_07135 3c6552db455b3b2d701629832a3d98f7 252 SUPERFAMILY SSF53218 1 205 5.5E-41 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily A3L08_07135 3c6552db455b3b2d701629832a3d98f7 252 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 3 174 1.1E-25 T 23-10-2018 IPR001453 MoaB/Mog domain A3L08_07135 3c6552db455b3b2d701629832a3d98f7 252 SMART SM00852 4 179 2.4E-42 T 23-10-2018 IPR001453 MoaB/Mog domain A3L08_07135 3c6552db455b3b2d701629832a3d98f7 252 Pfam PF00994 Probable molybdopterin binding domain 4 176 1.1E-35 T 23-10-2018 IPR001453 MoaB/Mog domain A3L08_07135 3c6552db455b3b2d701629832a3d98f7 252 Gene3D G3DSA:3.40.980.10 2 179 2.5E-54 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily A3L08_07135 3c6552db455b3b2d701629832a3d98f7 252 Hamap MF_00226_A Putative competence-damage inducible protein [cinA]. 1 249 38.55 T 23-10-2018 IPR023055 Putative competence-damage inducible protein, Archaea A3L08_08175 23168ff9587c484c0ea9dbfe4edab807 432 Gene3D G3DSA:3.40.30.10 23 172 9.8E-12 T 23-10-2018 A3L08_08175 23168ff9587c484c0ea9dbfe4edab807 432 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 209 414 8.6E-10 T 23-10-2018 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 A3L08_08175 23168ff9587c484c0ea9dbfe4edab807 432 SUPERFAMILY SSF52833 29 170 2.15E-12 T 23-10-2018 IPR036249 Thioredoxin-like superfamily A3L08_05835 14ec9a677e74a67e19a6e05310a01f9d 362 SUPERFAMILY SSF51735 1 169 5.31E-22 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L08_05835 14ec9a677e74a67e19a6e05310a01f9d 362 SUPERFAMILY SSF55347 118 252 1.83E-39 T 23-10-2018 A3L08_05835 14ec9a677e74a67e19a6e05310a01f9d 362 Pfam PF03435 Saccharopine dehydrogenase NADP binding domain 3 113 3.4E-18 T 23-10-2018 IPR005097 Saccharopine dehydrogenase, NADP binding domain GO:0016491|GO:0055114 A3L08_05835 14ec9a677e74a67e19a6e05310a01f9d 362 Pfam PF16653 Saccharopine dehydrogenase C-terminal domain 117 349 1.2E-29 T 23-10-2018 IPR032095 Saccharopine dehydrogenase, C-terminal Reactome: R-HSA-71064 A3L08_05835 14ec9a677e74a67e19a6e05310a01f9d 362 Gene3D G3DSA:3.40.50.720 2 349 6.2E-132 T 23-10-2018 A3L08_05835 14ec9a677e74a67e19a6e05310a01f9d 362 Gene3D G3DSA:3.30.360.10 118 299 6.2E-132 T 23-10-2018 A3L08_00720 45fad66b8b4ea9e51678aafcd17f93dd 351 PIRSF PIRSF005895 1 351 8.7E-159 T 23-10-2018 IPR014435 N(4)-bis(aminopropyl)spermidine synthase GO:0006596|GO:0016765 A3L08_00720 45fad66b8b4ea9e51678aafcd17f93dd 351 Gene3D G3DSA:3.40.50.150 101 326 1.2E-86 T 23-10-2018 A3L08_00720 45fad66b8b4ea9e51678aafcd17f93dd 351 Pfam PF01861 Protein of unknown function DUF43 106 350 9.5E-121 T 23-10-2018 IPR002723 N(4)-bis(aminopropyl)spermidine synthase, C-terminal A3L08_00720 45fad66b8b4ea9e51678aafcd17f93dd 351 SUPERFAMILY SSF53335 165 282 7.44E-9 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L08_00720 45fad66b8b4ea9e51678aafcd17f93dd 351 Gene3D G3DSA:1.10.10.10 1 83 8.2E-32 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L08_00720 45fad66b8b4ea9e51678aafcd17f93dd 351 Hamap MF_01947 N(4)-bis(aminopropyl)spermidine synthase [bpsA]. 15 351 50.427 T 23-10-2018 IPR014435 N(4)-bis(aminopropyl)spermidine synthase GO:0006596|GO:0016765 A3L08_09325 289146759e0b9bc1b9e31b2ff9023662 201 Pfam PF01895 PhoU domain 18 100 1.4E-8 T 23-10-2018 IPR026022 PhoU domain A3L08_09325 289146759e0b9bc1b9e31b2ff9023662 201 Pfam PF02080 TrkA-C domain 124 190 3.3E-15 T 23-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A3L08_09325 289146759e0b9bc1b9e31b2ff9023662 201 Gene3D G3DSA:1.20.58.220 7 115 7.8E-20 T 23-10-2018 IPR038078 PhoU-like domain superfamily A3L08_09325 289146759e0b9bc1b9e31b2ff9023662 201 Gene3D G3DSA:3.30.70.1450 116 201 1.1E-23 T 23-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 A3L08_09325 289146759e0b9bc1b9e31b2ff9023662 201 SUPERFAMILY SSF109755 11 114 7.59E-15 T 23-10-2018 A3L08_09325 289146759e0b9bc1b9e31b2ff9023662 201 SUPERFAMILY SSF116726 107 190 5.49E-21 T 23-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 A3L08_06150 d4318c3f6ce1ca2c84d7c45fb5d33266 447 SUPERFAMILY SSF53383 24 430 3.5E-130 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A3L08_06150 d4318c3f6ce1ca2c84d7c45fb5d33266 447 Gene3D G3DSA:3.40.640.10 63 328 4.9E-149 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A3L08_06150 d4318c3f6ce1ca2c84d7c45fb5d33266 447 Pfam PF00202 Aminotransferase class-III 25 428 6.9E-114 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A3L08_06150 d4318c3f6ce1ca2c84d7c45fb5d33266 447 Gene3D G3DSA:3.90.1150.10 9 424 4.9E-149 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A3L08_06150 d4318c3f6ce1ca2c84d7c45fb5d33266 447 PIRSF PIRSF000521 30 133 5.8E-7 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A3L08_06150 d4318c3f6ce1ca2c84d7c45fb5d33266 447 PIRSF PIRSF000521 127 431 4.9E-35 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A3L08_06150 d4318c3f6ce1ca2c84d7c45fb5d33266 447 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 245 282 - T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A3L08_02890 fc7434918d687ba26d7eb2a021d3c280 278 SUPERFAMILY SSF103481 39 133 1.57E-12 T 23-10-2018 A3L08_02890 fc7434918d687ba26d7eb2a021d3c280 278 SUPERFAMILY SSF103481 176 273 6.15E-14 T 23-10-2018 A3L08_02890 fc7434918d687ba26d7eb2a021d3c280 278 Pfam PF00892 EamA-like transporter family 7 131 4.1E-20 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A3L08_02890 fc7434918d687ba26d7eb2a021d3c280 278 Pfam PF00892 EamA-like transporter family 140 268 2.4E-17 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A3L08_07755 2bd2f1fbca0966e235c56ef6786f2b2a 234 Pfam PF12698 ABC-2 family transporter protein 51 228 1.3E-8 T 23-10-2018 A3L08_09145 78040c95fa25a1f6d2ead143d79e6f13 151 SMART SM00670 2 127 1.0E-8 T 23-10-2018 IPR002716 PIN domain A3L08_09145 78040c95fa25a1f6d2ead143d79e6f13 151 SUPERFAMILY SSF88723 1 128 1.49E-18 T 23-10-2018 IPR029060 PIN-like domain superfamily A3L08_09145 78040c95fa25a1f6d2ead143d79e6f13 151 Gene3D G3DSA:3.40.50.1010 4 140 1.3E-7 T 23-10-2018 A3L08_09145 78040c95fa25a1f6d2ead143d79e6f13 151 Pfam PF01850 PIN domain 4 130 1.6E-15 T 23-10-2018 IPR002716 PIN domain A3L08_05115 96700a60b29c54eacf51736f620ebc01 399 Gene3D G3DSA:3.40.640.10 53 294 5.9E-143 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A3L08_05115 96700a60b29c54eacf51736f620ebc01 399 Pfam PF00155 Aminotransferase class I and II 31 375 5.9E-62 T 23-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A3L08_05115 96700a60b29c54eacf51736f620ebc01 399 Gene3D G3DSA:3.90.1150.10 24 390 5.9E-143 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A3L08_05115 96700a60b29c54eacf51736f620ebc01 399 SUPERFAMILY SSF53383 12 394 6.78E-106 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A3L08_05655 d3bf06624e3e3e9fbbfbf5e7f6c5001f 421 SUPERFAMILY SSF50475 5 279 1.26E-63 T 23-10-2018 A3L08_05655 d3bf06624e3e3e9fbbfbf5e7f6c5001f 421 Pfam PF01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 7 385 7.3E-99 T 23-10-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 A3L08_05655 d3bf06624e3e3e9fbbfbf5e7f6c5001f 421 Gene3D G3DSA:3.40.1670.10 296 408 8.5E-38 T 23-10-2018 A3L08_05655 d3bf06624e3e3e9fbbfbf5e7f6c5001f 421 TIGRFAM TIGR00148 TIGR00148: decarboxylase, UbiD family 3 409 3.1E-112 T 23-10-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 A3L08_05655 d3bf06624e3e3e9fbbfbf5e7f6c5001f 421 SUPERFAMILY SSF143968 282 419 1.96E-41 T 23-10-2018 A3L08_04645 057f9d9f87b16087965c23f4506e0c42 264 SUPERFAMILY SSF46785 8 96 4.19E-7 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L08_04645 057f9d9f87b16087965c23f4506e0c42 264 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 10 78 8.3E-19 T 23-10-2018 IPR002831 Transcription regulator TrmB, N-terminal A3L08_04645 057f9d9f87b16087965c23f4506e0c42 264 Gene3D G3DSA:3.30.870.10 122 264 1.4E-80 T 23-10-2018 A3L08_04645 057f9d9f87b16087965c23f4506e0c42 264 Gene3D G3DSA:1.10.10.10 1 75 1.8E-21 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L08_04645 057f9d9f87b16087965c23f4506e0c42 264 Pfam PF11495 Archaeal transcriptional regulator TrmB 126 262 2.8E-5 T 23-10-2018 IPR021586 Transcription regulator TrmB, C-terminal A3L08_00215 5fed7f31f4ca8c484a34cf0a6d5efa78 126 Pfam PF09946 Predicted membrane protein (DUF2178) 14 97 2.3E-13 T 23-10-2018 IPR019235 Protein of unknown function DUF2178, transmembrane A3L08_05755 11a372db0958b93ecbf68b6866054740 1051 Pfam PF05123 S-layer like family, N-terminal region 4 120 2.2E-41 T 23-10-2018 IPR022650 S-layer protein, N-terminal A3L08_05755 11a372db0958b93ecbf68b6866054740 1051 TIGRFAM TIGR01564 S_layer_MJ: S-layer protein 4 103 1.0E-36 T 23-10-2018 IPR006454 S-layer protein GO:0005618 A3L08_05755 11a372db0958b93ecbf68b6866054740 1051 TIGRFAM TIGR01564 S_layer_MJ: S-layer protein 726 1048 3.6E-37 T 23-10-2018 IPR006454 S-layer protein GO:0005618 A3L08_05755 11a372db0958b93ecbf68b6866054740 1051 Pfam PF05124 S-layer like family, C-terminal region 845 1048 2.1E-34 T 23-10-2018 IPR022651 S-layer protein, C-terminal A3L08_05665 75174fc1c459c3a8ca37e8bd965634b2 267 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 2 221 3.6E-53 T 23-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 A3L08_05665 75174fc1c459c3a8ca37e8bd965634b2 267 SUPERFAMILY SSF55120 1 233 8.49E-66 T 23-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 A3L08_05665 75174fc1c459c3a8ca37e8bd965634b2 267 Gene3D G3DSA:3.30.70.580 1 103 7.7E-24 T 23-10-2018 A3L08_05665 75174fc1c459c3a8ca37e8bd965634b2 267 Pfam PF01416 tRNA pseudouridine synthase 129 228 2.8E-24 T 23-10-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 A3L08_05665 75174fc1c459c3a8ca37e8bd965634b2 267 PIRSF PIRSF001430 1 243 2.0E-76 T 23-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 A3L08_05665 75174fc1c459c3a8ca37e8bd965634b2 267 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 1 227 30.676 T 23-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 A3L08_05665 75174fc1c459c3a8ca37e8bd965634b2 267 Gene3D G3DSA:3.30.70.660 104 226 1.6E-26 T 23-10-2018 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0003723|GO:0009982 A3L08_08195 69c12fe5b519e33e9698af836f288c3c 286 SUPERFAMILY SSF161098 48 273 1.96E-66 T 23-10-2018 IPR035906 MetI-like superfamily A3L08_08195 69c12fe5b519e33e9698af836f288c3c 286 Gene3D G3DSA:1.10.3720.10 44 282 3.5E-74 T 23-10-2018 IPR035906 MetI-like superfamily A3L08_08195 69c12fe5b519e33e9698af836f288c3c 286 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 80 272 7.1E-22 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A3L08_01660 e1248ccc045979a067288b63efab0f74 285 Gene3D G3DSA:3.40.50.150 99 277 3.5E-26 T 23-10-2018 A3L08_01660 e1248ccc045979a067288b63efab0f74 285 Pfam PF13649 Methyltransferase domain 131 232 2.3E-9 T 23-10-2018 A3L08_01660 e1248ccc045979a067288b63efab0f74 285 SUPERFAMILY SSF53335 91 264 7.5E-35 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L08_08845 b2f87ce57d04a3b98ba983e548a63321 421 Gene3D G3DSA:3.20.20.140 55 341 2.3E-124 T 23-10-2018 A3L08_08845 b2f87ce57d04a3b98ba983e548a63321 421 SUPERFAMILY SSF51556 54 344 4.3E-84 T 23-10-2018 IPR032466 Metal-dependent hydrolase A3L08_08845 b2f87ce57d04a3b98ba983e548a63321 421 SUPERFAMILY SSF51338 12 404 1.18E-24 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A3L08_08845 b2f87ce57d04a3b98ba983e548a63321 421 Pfam PF01979 Amidohydrolase family 52 395 2.6E-61 T 23-10-2018 IPR006680 Amidohydrolase-related GO:0016787 A3L08_08845 b2f87ce57d04a3b98ba983e548a63321 421 Gene3D G3DSA:2.30.40.10 8 404 2.3E-124 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A3L08_07655 9624b45be2330f15e1c14668cd0b16b2 171 Pfam PF00994 Probable molybdopterin binding domain 17 159 2.5E-37 T 23-10-2018 IPR001453 MoaB/Mog domain A3L08_07655 9624b45be2330f15e1c14668cd0b16b2 171 PIRSF PIRSF006443 1 171 9.5E-59 T 23-10-2018 IPR012245 Molybdenum cofactor biosynthesis protein MoaB GO:0006777 A3L08_07655 9624b45be2330f15e1c14668cd0b16b2 171 Gene3D G3DSA:3.40.980.10 12 170 2.0E-49 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily A3L08_07655 9624b45be2330f15e1c14668cd0b16b2 171 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 14 159 3.2E-37 T 23-10-2018 IPR001453 MoaB/Mog domain A3L08_07655 9624b45be2330f15e1c14668cd0b16b2 171 SUPERFAMILY SSF53218 13 168 1.31E-44 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily A3L08_07655 9624b45be2330f15e1c14668cd0b16b2 171 SMART SM00852 17 165 2.9E-28 T 23-10-2018 IPR001453 MoaB/Mog domain A3L08_01065 30287662ea66122838144cafb0712f61 137 Gene3D G3DSA:2.60.120.460 1 137 4.2E-50 T 23-10-2018 IPR035917 YjbQ-like superfamily A3L08_01065 30287662ea66122838144cafb0712f61 137 Pfam PF01894 Uncharacterised protein family UPF0047 20 134 5.8E-36 T 23-10-2018 IPR001602 Uncharacterised protein family UPF0047 A3L08_01065 30287662ea66122838144cafb0712f61 137 PIRSF PIRSF004681 1 137 1.5E-38 T 23-10-2018 IPR001602 Uncharacterised protein family UPF0047 A3L08_01065 30287662ea66122838144cafb0712f61 137 SUPERFAMILY SSF111038 1 137 6.02E-44 T 23-10-2018 IPR035917 YjbQ-like superfamily A3L08_01065 30287662ea66122838144cafb0712f61 137 TIGRFAM TIGR00149 TIGR00149_YjbQ: secondary thiamine-phosphate synthase enzyme 9 137 8.0E-39 T 23-10-2018 IPR001602 Uncharacterised protein family UPF0047 A3L08_09605 2c65a0a8296b81469f42c76b15d5a92e 109 Pfam PF01588 Putative tRNA binding domain 14 107 7.7E-25 T 23-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 A3L08_09605 2c65a0a8296b81469f42c76b15d5a92e 109 Gene3D G3DSA:2.40.50.140 1 109 8.3E-35 T 23-10-2018 A3L08_09605 2c65a0a8296b81469f42c76b15d5a92e 109 TIGRFAM TIGR00399 metG_C_term: methionine--tRNA ligase, beta subunit 4 108 2.9E-36 T 23-10-2018 IPR004495 Methionyl-tRNA synthetase, beta subunit, C-terminal GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A3L08_09605 2c65a0a8296b81469f42c76b15d5a92e 109 SUPERFAMILY SSF50249 8 108 8.81E-30 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L08_08630 43a3831f4b4355db619a36fd405190cc 376 Pfam PF00465 Iron-containing alcohol dehydrogenase 6 368 2.5E-98 T 23-10-2018 IPR001670 Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 A3L08_08630 43a3831f4b4355db619a36fd405190cc 376 Gene3D G3DSA:1.20.1090.10 186 376 1.8E-54 T 23-10-2018 A3L08_08630 43a3831f4b4355db619a36fd405190cc 376 Gene3D G3DSA:3.40.50.1970 1 184 2.5E-43 T 23-10-2018 A3L08_08630 43a3831f4b4355db619a36fd405190cc 376 SUPERFAMILY SSF56796 2 375 1.05E-96 T 23-10-2018 A3L08_04040 61391402ad3385229caf276ce17297ea 256 SUPERFAMILY SSF75217 4 254 1.75E-46 T 23-10-2018 IPR029028 Alpha/beta knot methyltransferases A3L08_04040 61391402ad3385229caf276ce17297ea 256 SUPERFAMILY SSF50249 91 156 1.18E-11 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L08_04040 61391402ad3385229caf276ce17297ea 256 Gene3D G3DSA:2.40.50.140 91 153 7.3E-76 T 23-10-2018 A3L08_04040 61391402ad3385229caf276ce17297ea 256 Gene3D G3DSA:3.40.1280.10 5 252 7.3E-76 T 23-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal A3L08_04040 61391402ad3385229caf276ce17297ea 256 Pfam PF02598 Putative RNA methyltransferase 5 249 6.3E-50 T 23-10-2018 IPR003750 Putative RNA methyltransferase A3L08_03220 9414ecbd3875cfec1b9988c771905750 197 ProSitePatterns PS01236 PdxT/SNO family family signature. 47 57 - T 23-10-2018 IPR021196 PdxT/SNO family, conserved site KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A3L08_03220 9414ecbd3875cfec1b9988c771905750 197 Gene3D G3DSA:3.40.50.880 1 197 9.2E-69 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A3L08_03220 9414ecbd3875cfec1b9988c771905750 197 Pfam PF01174 SNO glutamine amidotransferase family 6 195 2.9E-58 T 23-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A3L08_03220 9414ecbd3875cfec1b9988c771905750 197 TIGRFAM TIGR03800 PLP_synth_Pdx2: pyridoxal 5'-phosphate synthase, glutaminase subunit Pdx2 3 193 1.1E-76 T 23-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A3L08_03220 9414ecbd3875cfec1b9988c771905750 197 Hamap MF_01615 Pyridoxal 5'-phosphate synthase subunit PdxT [pdxT]. 4 195 35.416 T 23-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A3L08_03220 9414ecbd3875cfec1b9988c771905750 197 PIRSF PIRSF005639 1 197 1.2E-68 T 23-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A3L08_03220 9414ecbd3875cfec1b9988c771905750 197 SUPERFAMILY SSF52317 2 194 2.22E-49 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A3L08_09505 7a771407e4fcb5195ceae829f016aab5 51 Gene3D G3DSA:1.10.1620.10 2 51 1.1E-18 T 23-10-2018 IPR023626 Ribosomal protein L39e domain superfamily A3L08_09505 7a771407e4fcb5195ceae829f016aab5 51 SUPERFAMILY SSF48662 4 50 1.44E-18 T 23-10-2018 IPR023626 Ribosomal protein L39e domain superfamily A3L08_09505 7a771407e4fcb5195ceae829f016aab5 51 Hamap MF_00629 50S ribosomal protein L39e [rpl39e]. 1 51 19.186 T 23-10-2018 IPR000077 Ribosomal protein L39e GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L08_09505 7a771407e4fcb5195ceae829f016aab5 51 Pfam PF00832 Ribosomal L39 protein 9 50 2.2E-21 T 23-10-2018 IPR000077 Ribosomal protein L39e GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L08_03980 0dc89991da3ed9b66621dbaf5f7c82d7 222 Pfam PF03192 Pyrococcus protein of unknown function, DUF257 8 211 1.3E-63 T 23-10-2018 IPR005489 Protein of unknown function DUF257 A3L08_03980 0dc89991da3ed9b66621dbaf5f7c82d7 222 Gene3D G3DSA:3.40.50.11570 2 215 3.2E-55 T 23-10-2018 A3L08_05205 2568e7fe644f9885caf75f2f0c0a9047 231 Pfam PF01963 TraB family 9 222 2.2E-12 T 23-10-2018 IPR002816 Pheromone shutdown, TraB A3L08_04130 5d6e5ab09035289eaff2a6faee7c49fc 184 Hamap MF_01365_A 50S ribosomal protein L6 [rplF]. 2 178 39.428 T 23-10-2018 IPR019907 Ribosomal protein L6P, archaea GO:0003735|GO:0005840|GO:0006412|GO:0019843 A3L08_04130 5d6e5ab09035289eaff2a6faee7c49fc 184 PIRSF PIRSF002162 5 182 3.8E-41 T 23-10-2018 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_04130 5d6e5ab09035289eaff2a6faee7c49fc 184 TIGRFAM TIGR03653 uL6_arch: ribosomal protein uL6 8 177 5.7E-79 T 23-10-2018 IPR019907 Ribosomal protein L6P, archaea GO:0003735|GO:0005840|GO:0006412|GO:0019843 A3L08_04130 5d6e5ab09035289eaff2a6faee7c49fc 184 Pfam PF00347 Ribosomal protein L6 13 85 2.0E-20 T 23-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_04130 5d6e5ab09035289eaff2a6faee7c49fc 184 Pfam PF00347 Ribosomal protein L6 97 171 4.3E-15 T 23-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_04130 5d6e5ab09035289eaff2a6faee7c49fc 184 SUPERFAMILY SSF56053 86 177 1.32E-30 T 23-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_04130 5d6e5ab09035289eaff2a6faee7c49fc 184 SUPERFAMILY SSF56053 8 85 5.52E-24 T 23-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_04130 5d6e5ab09035289eaff2a6faee7c49fc 184 Gene3D G3DSA:3.90.930.12 86 182 7.3E-38 T 23-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_04130 5d6e5ab09035289eaff2a6faee7c49fc 184 Gene3D G3DSA:3.90.930.12 6 85 1.0E-31 T 23-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_04130 5d6e5ab09035289eaff2a6faee7c49fc 184 ProSitePatterns PS00700 Ribosomal protein L6 signature 2. 156 177 - T 23-10-2018 IPR002359 Ribosomal protein L6, conserved site-2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_03375 7c162822faa74993f3701d523a64dc93 61 SMART SM01389 3 61 8.1E-31 T 23-10-2018 IPR022800 Spt4/RpoE2 zinc finger Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-75955 A3L08_03375 7c162822faa74993f3701d523a64dc93 61 ProDom PD019197 RNA DNA-DIRECTED POLYMERASE SUBUNIT E'' POLYMERASE RPOE2 TRANSFERASE NUCLEOTIDYLTRANSFERASE E 18 60 3.0E-14 T 23-10-2018 IPR007178 Archaeal transcription elongation factor Spt4 GO:0006355 A3L08_03375 7c162822faa74993f3701d523a64dc93 61 SUPERFAMILY SSF63393 3 61 4.71E-23 T 23-10-2018 IPR029040 RNA polymerase subunit RPABC4/transcription elongation factor Spt4 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-75955 A3L08_03375 7c162822faa74993f3701d523a64dc93 61 Pfam PF06093 Spt4/RpoE2 zinc finger 3 61 1.3E-16 T 23-10-2018 IPR022800 Spt4/RpoE2 zinc finger Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-75955 A3L08_03375 7c162822faa74993f3701d523a64dc93 61 Gene3D G3DSA:2.20.28.90 1 61 2.8E-32 T 23-10-2018 IPR038589 Archaeal transcription elongation factor Spt4 superfamily A3L08_03375 7c162822faa74993f3701d523a64dc93 61 Hamap MF_00949 Transcription elongation factor Spt4 [spt4]. 5 61 29.044 T 23-10-2018 IPR007178 Archaeal transcription elongation factor Spt4 GO:0006355 A3L08_05405 c8ebb04ccc79b0b09325e3e44ed47abc 349 Pfam PF01901 Putative O-antigen polymerase 113 323 7.7E-17 T 23-10-2018 IPR002760 Putative O-antigen polymerase A3L08_01295 e835f098f6f27f5ebac6bf0d2b905654 436 PIRSF PIRSF006809 1 421 8.7E-121 T 23-10-2018 IPR016496 GTPase HflX GO:0005525 A3L08_01295 e835f098f6f27f5ebac6bf0d2b905654 436 Gene3D G3DSA:3.40.50.11060 8 129 4.6E-34 T 23-10-2018 A3L08_01295 e835f098f6f27f5ebac6bf0d2b905654 436 Pfam PF01926 50S ribosome-binding GTPase 189 307 3.1E-21 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L08_01295 e835f098f6f27f5ebac6bf0d2b905654 436 SUPERFAMILY SSF52540 188 389 5.55E-39 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_01295 e835f098f6f27f5ebac6bf0d2b905654 436 Pfam PF13167 GTP-binding GTPase N-terminal 17 100 1.9E-24 T 23-10-2018 IPR025121 GTPase HflX, N-terminal A3L08_01295 e835f098f6f27f5ebac6bf0d2b905654 436 Pfam PF16360 GTP-binding GTPase Middle Region 103 180 1.1E-17 T 23-10-2018 IPR032305 GTP-binding protein, middle domain A3L08_01295 e835f098f6f27f5ebac6bf0d2b905654 436 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 188 208 5.1E-7 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L08_01295 e835f098f6f27f5ebac6bf0d2b905654 436 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 254 272 5.1E-7 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L08_01295 e835f098f6f27f5ebac6bf0d2b905654 436 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 209 227 5.1E-7 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L08_01295 e835f098f6f27f5ebac6bf0d2b905654 436 Gene3D G3DSA:3.40.50.300 188 361 1.6E-42 T 23-10-2018 A3L08_01295 e835f098f6f27f5ebac6bf0d2b905654 436 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 9 343 9.8E-94 T 23-10-2018 IPR016496 GTPase HflX GO:0005525 A3L08_01295 e835f098f6f27f5ebac6bf0d2b905654 436 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 188 325 3.5E-13 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A3L08_01295 e835f098f6f27f5ebac6bf0d2b905654 436 Hamap MF_00900 GTPase HflX [hflX]. 17 391 42.697 T 23-10-2018 IPR016496 GTPase HflX GO:0005525 A3L08_03590 c9da34bae06c4c9e5d8c767042958841 204 Gene3D G3DSA:3.40.50.300 1 186 2.7E-50 T 23-10-2018 A3L08_03590 c9da34bae06c4c9e5d8c767042958841 204 SUPERFAMILY SSF52540 2 182 1.35E-30 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_03590 c9da34bae06c4c9e5d8c767042958841 204 Pfam PF01926 50S ribosome-binding GTPase 2 129 5.7E-18 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A3L08_03590 c9da34bae06c4c9e5d8c767042958841 204 Hamap MF_00321 Probable GTP-binding protein EngB [engB]. 1 180 21.678 T 23-10-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 A3L08_09575 57d5782845bf3f64bde04fbb1b87119b 125 SMART SM00748 1 105 9.3E-27 T 23-10-2018 IPR007842 HEPN domain A3L08_09575 57d5782845bf3f64bde04fbb1b87119b 125 Pfam PF05168 HEPN domain 1 111 3.6E-23 T 23-10-2018 IPR007842 HEPN domain A3L08_09575 57d5782845bf3f64bde04fbb1b87119b 125 Gene3D G3DSA:1.20.120.330 1 113 3.4E-21 T 23-10-2018 A3L08_09575 57d5782845bf3f64bde04fbb1b87119b 125 SUPERFAMILY SSF81593 1 114 1.37E-26 T 23-10-2018 A3L08_00100 594fdaf2c7fa5f5a00ad18a1e2c92f46 110 SUPERFAMILY SSF50447 1 72 7.77E-17 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily A3L08_00100 594fdaf2c7fa5f5a00ad18a1e2c92f46 110 Gene3D G3DSA:2.40.10.230 1 75 2.6E-25 T 23-10-2018 IPR038664 H/ACA RNP complex subunit Gar1/Naf1, Cbf5-binding domain A3L08_00100 594fdaf2c7fa5f5a00ad18a1e2c92f46 110 Pfam PF04410 Gar1/Naf1 RNA binding region 2 58 6.2E-9 T 23-10-2018 IPR007504 H/ACA ribonucleoprotein complex, subunit Gar1/Naf1 GO:0001522|GO:0042254 A3L08_00100 594fdaf2c7fa5f5a00ad18a1e2c92f46 110 ProDom PD064583 RNA-BINDING GAR1 COMPONENT RNP SNORNP HOMOLOG NUCLEOLAR PROCESSING RRNA VNG1366H 1 71 2.0E-26 T 23-10-2018 IPR020321 H/ACA ribonucleoprotein complex, subunit Gar1, archaea GO:0001522|GO:0042254 A3L08_02505 16f8b61fbd4d12d550a45db9bffbc465 257 Pfam PF02080 TrkA-C domain 156 227 6.0E-12 T 23-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A3L08_02505 16f8b61fbd4d12d550a45db9bffbc465 257 SUPERFAMILY SSF116726 145 228 4.19E-14 T 23-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 A3L08_02505 16f8b61fbd4d12d550a45db9bffbc465 257 Gene3D G3DSA:3.30.70.1450 153 238 1.4E-15 T 23-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 A3L08_00840 44edcca5cf44565e6569abc437f835d9 378 Gene3D G3DSA:1.20.1250.20 1 190 5.9E-43 T 23-10-2018 A3L08_00840 44edcca5cf44565e6569abc437f835d9 378 Gene3D G3DSA:1.20.1250.20 193 364 1.3E-25 T 23-10-2018 A3L08_00840 44edcca5cf44565e6569abc437f835d9 378 Pfam PF07690 Major Facilitator Superfamily 11 330 2.5E-44 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A3L08_00840 44edcca5cf44565e6569abc437f835d9 378 SUPERFAMILY SSF103473 2 360 5.36E-71 T 23-10-2018 IPR036259 MFS transporter superfamily A3L08_00090 5fd5cae94534695718fffb9d7f40e3bd 164 Gene3D G3DSA:3.60.21.10 1 164 1.6E-41 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like A3L08_00090 5fd5cae94534695718fffb9d7f40e3bd 164 SUPERFAMILY SSF56300 3 163 3.63E-37 T 23-10-2018 A3L08_00090 5fd5cae94534695718fffb9d7f40e3bd 164 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 3 152 3.9E-26 T 23-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 A3L08_00090 5fd5cae94534695718fffb9d7f40e3bd 164 TIGRFAM TIGR00040 yfcE: phosphodiesterase, MJ0936 family 3 158 3.4E-34 T 23-10-2018 IPR000979 Phosphodiesterase MJ0936/Vps29 Reactome: R-HSA-3238698 A3L08_08570 36cc600d57fe44d50ea57cd36346cba7 91 PIRSF PIRSF028732 1 91 1.5E-40 T 23-10-2018 IPR013795 DNA/RNA-binding protein Alba GO:0003677|GO:0003723|GO:0005737 A3L08_08570 36cc600d57fe44d50ea57cd36346cba7 91 TIGRFAM TIGR00285 TIGR00285: DNA-binding protein Alba 4 90 5.7E-46 T 23-10-2018 IPR013795 DNA/RNA-binding protein Alba GO:0003677|GO:0003723|GO:0005737 A3L08_08570 36cc600d57fe44d50ea57cd36346cba7 91 Hamap MF_01122 DNA/RNA-binding protein Alba [albA]. 1 90 28.162 T 23-10-2018 IPR013795 DNA/RNA-binding protein Alba GO:0003677|GO:0003723|GO:0005737 A3L08_08570 36cc600d57fe44d50ea57cd36346cba7 91 SUPERFAMILY SSF82704 5 90 1.7E-27 T 23-10-2018 IPR036882 Alba-like domain superfamily GO:0003676 A3L08_08570 36cc600d57fe44d50ea57cd36346cba7 91 ProDom PD010497 ALBA DNA-BINDING DNA/RNA-BINDING RNA-BINDING ACETYLATION 3D-STRUCTURE DNA CONDENSATION AF1 SSO10B 8 90 7.0E-40 T 23-10-2018 A3L08_08570 36cc600d57fe44d50ea57cd36346cba7 91 Gene3D G3DSA:3.30.110.20 2 90 7.1E-39 T 23-10-2018 IPR036882 Alba-like domain superfamily GO:0003676 A3L08_08570 36cc600d57fe44d50ea57cd36346cba7 91 Pfam PF01918 Alba 6 66 1.6E-22 T 23-10-2018 IPR002775 DNA/RNA-binding protein Alba-like GO:0003676 A3L08_00115 96b3b4184c541459bac7178eaf8c99f1 118 Pfam PF04430 Protein of unknown function (DUF498/DUF598) 7 115 1.1E-13 T 23-10-2018 IPR007523 NDUFAF3/Mth938 domain-containing protein A3L08_00115 96b3b4184c541459bac7178eaf8c99f1 118 Gene3D G3DSA:3.40.1230.10 1 118 1.1E-36 T 23-10-2018 IPR036748 MTH938-like superfamily A3L08_00115 96b3b4184c541459bac7178eaf8c99f1 118 SUPERFAMILY SSF64076 5 118 3.4E-36 T 23-10-2018 IPR036748 MTH938-like superfamily A3L08_02620 bec79b407b93fd1f096f1b142f8cb55a 422 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 229 417 9.5E-10 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A3L08_02620 bec79b407b93fd1f096f1b142f8cb55a 422 Gene3D G3DSA:1.10.3720.10 205 416 2.2E-13 T 23-10-2018 IPR035906 MetI-like superfamily A3L08_02620 bec79b407b93fd1f096f1b142f8cb55a 422 SUPERFAMILY SSF161098 210 405 1.96E-15 T 23-10-2018 IPR035906 MetI-like superfamily A3L08_01945 b8eb7f8ed12ace6bbfdfa304c3e5d0f5 301 SMART SM00769 165 284 1.8E-13 T 23-10-2018 IPR013990 Water stress and hypersensitive response domain GO:0009269 A3L08_01945 b8eb7f8ed12ace6bbfdfa304c3e5d0f5 301 Pfam PF03168 Late embryogenesis abundant protein 185 269 2.4E-11 T 23-10-2018 IPR004864 Late embryogenesis abundant protein, LEA_2 subgroup A3L08_01945 b8eb7f8ed12ace6bbfdfa304c3e5d0f5 301 Gene3D G3DSA:2.60.40.10 164 295 2.4E-30 T 23-10-2018 IPR013783 Immunoglobulin-like fold A3L08_01945 b8eb7f8ed12ace6bbfdfa304c3e5d0f5 301 Gene3D G3DSA:2.60.40.10 30 145 6.1E-10 T 23-10-2018 IPR013783 Immunoglobulin-like fold A3L08_01945 b8eb7f8ed12ace6bbfdfa304c3e5d0f5 301 SUPERFAMILY SSF117070 160 264 3.66E-16 T 23-10-2018 A3L08_08100 e01ff7784b476e8b4c3a154967d4cb59 588 Pfam PF06202 Amylo-alpha-1,6-glucosidase 233 576 3.2E-16 T 23-10-2018 IPR032790 Glycogen debranching enzyme, C-terminal KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-6798695|Reactome: R-HSA-70221 A3L08_08100 e01ff7784b476e8b4c3a154967d4cb59 588 Gene3D G3DSA:1.50.10.10 210 584 4.7E-47 T 23-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 A3L08_08100 e01ff7784b476e8b4c3a154967d4cb59 588 SUPERFAMILY SSF48208 228 581 1.28E-66 T 23-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 A3L08_04125 1334a742223019e325ffdc4e6fc49b55 130 Gene3D G3DSA:3.30.1490.10 70 128 1.5E-27 T 23-10-2018 A3L08_04125 1334a742223019e325ffdc4e6fc49b55 130 SUPERFAMILY SSF56047 3 130 1.31E-39 T 23-10-2018 IPR035987 Ribosomal protein S8 superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_04125 1334a742223019e325ffdc4e6fc49b55 130 Gene3D G3DSA:3.30.1370.30 1 69 7.0E-32 T 23-10-2018 A3L08_04125 1334a742223019e325ffdc4e6fc49b55 130 Pfam PF00410 Ribosomal protein S8 5 130 5.8E-28 T 23-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_04125 1334a742223019e325ffdc4e6fc49b55 130 ProSitePatterns PS00053 Ribosomal protein S8 signature. 100 117 - T 23-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_04125 1334a742223019e325ffdc4e6fc49b55 130 Hamap MF_01302_A 30S ribosomal protein S8 [rpsH]. 2 130 38.258 T 23-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_07635 4943f9061de26e7f0b79197a98c7d352 318 Hamap MF_00584 Putative HTH-type transcriptional regulatory protein . 2 300 28.81 T 23-10-2018 IPR020886 Transcription regulator HTH, Cro/C1-type DNA-binding GO:0003700|GO:0006355 A3L08_07635 4943f9061de26e7f0b79197a98c7d352 318 SUPERFAMILY SSF47413 126 185 4.02E-13 T 23-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A3L08_07635 4943f9061de26e7f0b79197a98c7d352 318 Pfam PF01381 Helix-turn-helix 131 184 1.1E-13 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A3L08_07635 4943f9061de26e7f0b79197a98c7d352 318 Gene3D G3DSA:1.10.260.40 129 186 1.5E-12 T 23-10-2018 A3L08_07635 4943f9061de26e7f0b79197a98c7d352 318 SMART SM00530 130 185 3.3E-13 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A3L08_05300 55c1b7de7ced4275bd774ccf39e93201 139 Gene3D G3DSA:2.20.28.10 69 123 1.5E-29 T 23-10-2018 A3L08_05300 55c1b7de7ced4275bd774ccf39e93201 139 Gene3D G3DSA:3.30.2320.50 2 130 1.5E-29 T 23-10-2018 A3L08_05300 55c1b7de7ced4275bd774ccf39e93201 139 Pfam PF01155 Hydrogenase/urease nickel incorporation, metallochaperone, hypA 1 131 1.4E-29 T 23-10-2018 IPR000688 Hydrogenase maturation factor HypA/HybF GO:0016151|GO:0051604 A3L08_05300 55c1b7de7ced4275bd774ccf39e93201 139 Hamap MF_00213 Hydrogenase maturation factor HypA [hypA]. 1 134 22.265 T 23-10-2018 IPR000688 Hydrogenase maturation factor HypA/HybF GO:0016151|GO:0051604 A3L08_05300 55c1b7de7ced4275bd774ccf39e93201 139 ProSitePatterns PS01249 Hydrogenases expression/synthesis hypA family signature. 34 76 - T 23-10-2018 IPR020538 Hydrogenase nickel incorporation protein HypA/HybF, conserved site A3L08_05300 55c1b7de7ced4275bd774ccf39e93201 139 PIRSF PIRSF004761 1 137 8.1E-37 T 23-10-2018 IPR000688 Hydrogenase maturation factor HypA/HybF GO:0016151|GO:0051604 A3L08_08300 04343845f46eeaf3a2bd383f03f8fbff 169 TIGRFAM TIGR04178 exo_archaeo: exosortase/archaeosortase family protein 70 154 8.7E-16 T 23-10-2018 IPR026392 Exosortase/Archaeosortase domain A3L08_08300 04343845f46eeaf3a2bd383f03f8fbff 169 TIGRFAM TIGR04293 archaeo_artF: archaeosortase family protein ArtF 10 161 3.1E-51 T 23-10-2018 IPR027557 Archaeosortase ArtF A3L08_08300 04343845f46eeaf3a2bd383f03f8fbff 169 Pfam PF09721 Transmembrane exosortase (Exosortase_EpsH) 14 153 9.3E-13 T 23-10-2018 IPR019127 Exosortase A3L08_02700 0189ac7d9658af15c8d28bd93e2efa75 135 PIRSF PIRSF005264 1 135 1.7E-44 T 23-10-2018 IPR002746 Uncharacterised protein family UPF0216 A3L08_02700 0189ac7d9658af15c8d28bd93e2efa75 135 Hamap MF_00585 UPF0216 protein . 4 135 26.878 T 23-10-2018 IPR002746 Uncharacterised protein family UPF0216 A3L08_02700 0189ac7d9658af15c8d28bd93e2efa75 135 Pfam PF01886 Protein of unknown function DUF61 6 132 2.9E-35 T 23-10-2018 IPR002746 Uncharacterised protein family UPF0216 A3L08_02700 0189ac7d9658af15c8d28bd93e2efa75 135 ProDom PD016056 UPF0216 PYRAB16100 PH0358 MTH949 MK1676 AF0460 PF0452 MJ1224 8 132 3.0E-33 T 23-10-2018 IPR002746 Uncharacterised protein family UPF0216 A3L08_01335 751b9733ce0fb749a9d777270bf56e3b 331 Gene3D G3DSA:3.40.50.970 98 324 1.6E-67 T 23-10-2018 A3L08_01335 751b9733ce0fb749a9d777270bf56e3b 331 Gene3D G3DSA:3.40.50.970 12 97 7.8E-11 T 23-10-2018 A3L08_01335 751b9733ce0fb749a9d777270bf56e3b 331 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 57 218 2.9E-24 T 23-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 A3L08_01335 751b9733ce0fb749a9d777270bf56e3b 331 SUPERFAMILY SSF52518 12 317 3.6E-74 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold A3L08_09060 19db280de1a29ae2eefbfd2fe22525e5 220 Pfam PF02616 Segregation and condensation protein ScpA 18 161 1.0E-14 T 23-10-2018 IPR003768 Segregation and condensation protein A A3L08_09060 19db280de1a29ae2eefbfd2fe22525e5 220 Gene3D G3DSA:1.10.10.580 147 216 2.6E-32 T 23-10-2018 IPR023093 ScpA-like, C-terminal A3L08_02030 fb55dd30bcfa4140ca5b2298b18c5417 339 PRINTS PR00169 Potassium channel signature 45 67 4.1E-7 T 23-10-2018 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 A3L08_02030 fb55dd30bcfa4140ca5b2298b18c5417 339 PRINTS PR00169 Potassium channel signature 74 100 4.1E-7 T 23-10-2018 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 A3L08_02030 fb55dd30bcfa4140ca5b2298b18c5417 339 Gene3D G3DSA:1.10.287.70 4 117 6.5E-22 T 23-10-2018 A3L08_02030 fb55dd30bcfa4140ca5b2298b18c5417 339 Pfam PF02254 TrkA-N domain 121 241 3.5E-18 T 23-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 A3L08_02030 fb55dd30bcfa4140ca5b2298b18c5417 339 Gene3D G3DSA:3.40.50.720 118 266 1.7E-27 T 23-10-2018 A3L08_02030 fb55dd30bcfa4140ca5b2298b18c5417 339 SUPERFAMILY SSF51735 116 264 4.73E-21 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L08_02030 fb55dd30bcfa4140ca5b2298b18c5417 339 Pfam PF07885 Ion channel 29 101 2.2E-17 T 23-10-2018 IPR013099 Potassium channel domain A3L08_02030 fb55dd30bcfa4140ca5b2298b18c5417 339 SUPERFAMILY SSF81324 8 137 4.45E-28 T 23-10-2018 A3L08_02915 15cdecc877bdea6883803c7df26964ac 578 SUPERFAMILY SSF88713 5 227 3.33E-13 T 23-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 A3L08_03900 cbcd177f36b42cc65a84dea20bb59cbb 401 PIRSF PIRSF015658 1 401 1.3E-166 T 23-10-2018 IPR005661 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit GO:0006814|GO:0016829 KEGG: 00620+4.1.1.3 A3L08_03900 cbcd177f36b42cc65a84dea20bb59cbb 401 TIGRFAM TIGR01109 Na_pump_decarbB: sodium ion-translocating decarboxylase, beta subunit 23 395 1.5E-157 T 23-10-2018 IPR005661 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit GO:0006814|GO:0016829 KEGG: 00620+4.1.1.3 A3L08_03900 cbcd177f36b42cc65a84dea20bb59cbb 401 Pfam PF03977 Na+-transporting oxaloacetate decarboxylase beta subunit 24 399 1.5E-157 T 23-10-2018 IPR005661 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit GO:0006814|GO:0016829 KEGG: 00620+4.1.1.3 A3L08_06775 46bdfc2e3ca42350b031fb83b14bd100 284 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 57 205 3.0E-40 T 23-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 A3L08_06775 46bdfc2e3ca42350b031fb83b14bd100 284 Gene3D G3DSA:3.40.50.970 68 261 1.6E-33 T 23-10-2018 A3L08_06775 46bdfc2e3ca42350b031fb83b14bd100 284 SUPERFAMILY SSF52518 19 274 1.84E-76 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold A3L08_09725 a50765b22f67e43b59bbd28daf6c63db 189 SMART SM01022 4 104 1.2E-24 T 23-10-2018 IPR007374 ASCH domain A3L08_09725 a50765b22f67e43b59bbd28daf6c63db 189 SUPERFAMILY SSF88697 1 102 4.67E-22 T 23-10-2018 IPR015947 PUA-like superfamily A3L08_09725 a50765b22f67e43b59bbd28daf6c63db 189 Pfam PF04266 ASCH domain 4 101 1.3E-16 T 23-10-2018 IPR007374 ASCH domain A3L08_07120 801a907815045d23ef1a9a215d004452 171 Pfam PF01923 Cobalamin adenosyltransferase 3 159 1.7E-49 T 23-10-2018 IPR016030 Cobalamin adenosyltransferase-like KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 A3L08_07120 801a907815045d23ef1a9a215d004452 171 SUPERFAMILY SSF89028 1 165 5.89E-51 T 23-10-2018 IPR036451 Cobalamin adenosyltransferase-like superfamily KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 A3L08_07120 801a907815045d23ef1a9a215d004452 171 TIGRFAM TIGR00636 PduO_Nterm: ATP:cob(I)alamin adenosyltransferase 4 170 7.6E-59 T 23-10-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 A3L08_07120 801a907815045d23ef1a9a215d004452 171 ProDom PD007457 TRANSFERASE ADENOSYLTRANSFERASE COBALAMIN ATP:COBIALAMIN ADENOSYLTRANSFERASE PDUO TYPE RELATED ACIDURIA YVQK 20 165 6.0E-67 T 23-10-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 A3L08_07120 801a907815045d23ef1a9a215d004452 171 Gene3D G3DSA:1.20.1200.10 24 171 3.6E-49 T 23-10-2018 IPR036451 Cobalamin adenosyltransferase-like superfamily KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 A3L08_05790 eff2edf51d52bf30196012d767029b5c 420 Gene3D G3DSA:3.20.20.140 3 233 9.7E-15 T 23-10-2018 A3L08_05790 eff2edf51d52bf30196012d767029b5c 420 SUPERFAMILY SSF89550 5 227 1.84E-14 T 23-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 A3L08_05790 eff2edf51d52bf30196012d767029b5c 420 TIGRFAM TIGR00375 TIGR00375: TIGR00375 family protein 5 380 9.7E-130 T 23-10-2018 IPR005287 Conserved hypothetical protein CHP00375 A3L08_09390 482a528b20bfb61b901c35173729a838 339 Gene3D G3DSA:3.90.870.10 2 211 5.8E-85 T 23-10-2018 A3L08_09390 482a528b20bfb61b901c35173729a838 339 Pfam PF01300 Telomere recombination 22 196 5.5E-60 T 23-10-2018 IPR006070 YrdC-like domain GO:0003725 A3L08_09390 482a528b20bfb61b901c35173729a838 339 PIRSF PIRSF004930 1 338 1.4E-130 T 23-10-2018 IPR010923 tRNA threonylcarbamoyladenosine biosynthesis protein SUA5 A3L08_09390 482a528b20bfb61b901c35173729a838 339 Gene3D G3DSA:3.40.50.11030 235 339 4.9E-39 T 23-10-2018 IPR038385 Threonylcarbamoyl-AMP synthase, C-terminal domain superfamily A3L08_09390 482a528b20bfb61b901c35173729a838 339 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 10 207 2.9E-66 T 23-10-2018 IPR006070 YrdC-like domain GO:0003725 A3L08_09390 482a528b20bfb61b901c35173729a838 339 SUPERFAMILY SSF55821 9 209 3.97E-68 T 23-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily A3L08_09390 482a528b20bfb61b901c35173729a838 339 Pfam PF03481 Putative GTP-binding controlling metal-binding 200 333 4.3E-27 T 23-10-2018 IPR005145 Putative GTP-binding controlling metal-binding domain A3L08_09025 7166b3e4246b475d52d9d12efe5f3585 158 SUPERFAMILY SSF46785 10 139 3.28E-26 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L08_09025 7166b3e4246b475d52d9d12efe5f3585 158 Gene3D G3DSA:1.10.10.10 2 102 8.3E-26 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L08_09025 7166b3e4246b475d52d9d12efe5f3585 158 Pfam PF03551 Transcriptional regulator PadR-like family 14 84 1.3E-18 T 23-10-2018 IPR005149 Transcription regulator PadR, N-terminal A3L08_01635 da7dec1e3b2f22511e163f02fe48aff2 249 Pfam PF03099 Biotin/lipoate A/B protein ligase family 54 158 6.3E-13 T 23-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 A3L08_01635 da7dec1e3b2f22511e163f02fe48aff2 249 SUPERFAMILY SSF55681 1 246 8.7E-71 T 23-10-2018 A3L08_01635 da7dec1e3b2f22511e163f02fe48aff2 249 Gene3D G3DSA:3.30.930.10 8 249 6.5E-64 T 23-10-2018 A3L08_02725 ca5f8a1d862a80dfa4970dd273b29047 346 TIGRFAM TIGR00335 primase_sml: putative DNA primase, eukaryotic-type, small subunit 12 329 1.7E-58 T 23-10-2018 IPR014052 DNA primase, small subunit, eukaryotic/archaeal GO:0003896|GO:0006269 Reactome: R-HSA-113501|Reactome: R-HSA-174411|Reactome: R-HSA-174430|Reactome: R-HSA-68952|Reactome: R-HSA-68962|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183 A3L08_02725 ca5f8a1d862a80dfa4970dd273b29047 346 Gene3D G3DSA:3.90.920.10 9 326 4.1E-120 T 23-10-2018 A3L08_02725 ca5f8a1d862a80dfa4970dd273b29047 346 Hamap MF_00700 DNA primase small subunit PriS [priS]. 11 343 23.606 T 23-10-2018 IPR023639 DNA primase small subunit PriS GO:0003896 A3L08_02725 ca5f8a1d862a80dfa4970dd273b29047 346 Pfam PF01896 DNA primase small subunit 96 306 1.4E-12 T 23-10-2018 IPR002755 DNA primase, small subunit GO:0003896|GO:0006269 Reactome: R-HSA-113501|Reactome: R-HSA-174411|Reactome: R-HSA-174430|Reactome: R-HSA-68952|Reactome: R-HSA-68962|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183 A3L08_02725 ca5f8a1d862a80dfa4970dd273b29047 346 Gene3D G3DSA:1.10.8.160 176 277 4.1E-120 T 23-10-2018 A3L08_02725 ca5f8a1d862a80dfa4970dd273b29047 346 SUPERFAMILY SSF56747 6 340 1.98E-93 T 23-10-2018 A3L08_03565 1b664371ae4e2f6c6d512f2709fbb3f1 137 SMART SM00670 6 112 3.5E-8 T 23-10-2018 IPR002716 PIN domain A3L08_03565 1b664371ae4e2f6c6d512f2709fbb3f1 137 Gene3D G3DSA:3.40.50.1010 5 135 1.3E-29 T 23-10-2018 A3L08_03565 1b664371ae4e2f6c6d512f2709fbb3f1 137 SUPERFAMILY SSF88723 6 129 1.57E-23 T 23-10-2018 IPR029060 PIN-like domain superfamily A3L08_03565 1b664371ae4e2f6c6d512f2709fbb3f1 137 Pfam PF04900 Fcf1 32 129 9.6E-8 T 23-10-2018 IPR006984 rRNA-processing protein Fcf1/Utp23 GO:0032040 A3L08_02755 37ee7615c09d91e7b52b5ad4b599f15e 396 Gene3D G3DSA:3.30.750.80 72 178 2.8E-37 T 23-10-2018 A3L08_02755 37ee7615c09d91e7b52b5ad4b599f15e 396 Gene3D G3DSA:2.30.130.10 1 70 1.5E-21 T 23-10-2018 IPR036974 PUA domain superfamily GO:0003723 A3L08_02755 37ee7615c09d91e7b52b5ad4b599f15e 396 SUPERFAMILY SSF53335 78 389 8.22E-68 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L08_02755 37ee7615c09d91e7b52b5ad4b599f15e 396 Gene3D G3DSA:3.40.50.150 179 396 4.7E-71 T 23-10-2018 A3L08_02755 37ee7615c09d91e7b52b5ad4b599f15e 396 SUPERFAMILY SSF88697 1 69 1.44E-17 T 23-10-2018 IPR015947 PUA-like superfamily A3L08_02755 37ee7615c09d91e7b52b5ad4b599f15e 396 Pfam PF10672 S-adenosylmethionine-dependent methyltransferase 169 334 1.6E-20 T 23-10-2018 IPR019614 S-adenosylmethionine-dependent methyltransferase GO:0008168 A3L08_02755 37ee7615c09d91e7b52b5ad4b599f15e 396 Pfam PF01472 PUA domain 3 74 3.8E-14 T 23-10-2018 IPR002478 PUA domain GO:0003723 A3L08_02755 37ee7615c09d91e7b52b5ad4b599f15e 396 SMART SM00359 2 87 1.4E-20 T 23-10-2018 IPR002478 PUA domain GO:0003723 A3L08_04010 09eb11a81c3125bcf6a88a547967e3c6 300 SUPERFAMILY SSF55681 9 295 1.47E-54 T 23-10-2018 A3L08_04010 09eb11a81c3125bcf6a88a547967e3c6 300 Gene3D G3DSA:3.30.930.10 1 299 1.4E-74 T 23-10-2018 A3L08_04010 09eb11a81c3125bcf6a88a547967e3c6 300 Pfam PF00152 tRNA synthetases class II (D, K and N) 3 293 9.3E-45 T 23-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 A3L08_00775 cbb2e983f6b28f03d39c4eaf4c9e2734 243 PIRSF PIRSF037724 1 237 9.8E-106 T 23-10-2018 IPR017271 Transcription regulator HTH, MJ1545, predicted A3L08_00775 cbb2e983f6b28f03d39c4eaf4c9e2734 243 SMART SM00530 26 81 1.0E-12 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A3L08_00775 cbb2e983f6b28f03d39c4eaf4c9e2734 243 Gene3D G3DSA:1.10.260.40 24 80 5.7E-11 T 23-10-2018 A3L08_00775 cbb2e983f6b28f03d39c4eaf4c9e2734 243 Pfam PF01381 Helix-turn-helix 28 75 4.1E-9 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A3L08_00775 cbb2e983f6b28f03d39c4eaf4c9e2734 243 SUPERFAMILY SSF47413 22 75 3.58E-12 T 23-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A3L08_02555 baad083670522778b56c8da7989431e9 304 Pfam PF02355 Protein export membrane protein 121 295 2.4E-30 T 23-10-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial A3L08_02555 baad083670522778b56c8da7989431e9 304 SUPERFAMILY SSF82866 124 289 5.1E-24 T 23-10-2018 A3L08_02555 baad083670522778b56c8da7989431e9 304 Hamap MF_01464_A Protein-export membrane protein SecF [secF]. 28 300 25.614 T 23-10-2018 IPR024921 Protein-export membrane protein SecF, archaeal GO:0016021|GO:0065002 A3L08_02555 baad083670522778b56c8da7989431e9 304 Gene3D G3DSA:1.20.1640.10 116 302 5.8E-13 T 23-10-2018 A3L08_06180 0d6a6b0ade007b5cee3a45687f692b65 179 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 40 158 2.2E-25 T 23-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L08_06180 0d6a6b0ade007b5cee3a45687f692b65 179 Gene3D G3DSA:3.30.460.80 12 134 1.5E-25 T 23-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L08_06180 0d6a6b0ade007b5cee3a45687f692b65 179 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 90 131 1.0E-12 T 23-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L08_06180 0d6a6b0ade007b5cee3a45687f692b65 179 SUPERFAMILY SSF143243 28 169 7.59E-31 T 23-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L08_05280 7e8590dcef39bac59e28e90b3542da04 158 SMART SM00418 30 94 0.0017 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L08_05280 7e8590dcef39bac59e28e90b3542da04 158 Gene3D G3DSA:1.10.10.10 2 85 2.6E-18 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L08_05280 7e8590dcef39bac59e28e90b3542da04 158 SUPERFAMILY SSF46785 6 136 1.5E-18 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L08_05280 7e8590dcef39bac59e28e90b3542da04 158 PIRSF PIRSF006707 2 157 5.5E-31 T 23-10-2018 IPR026282 DNA-binding protein, MJ1563 type A3L08_05280 7e8590dcef39bac59e28e90b3542da04 158 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 23 86 6.5E-8 T 23-10-2018 IPR002831 Transcription regulator TrmB, N-terminal A3L08_07745 6f2a6537ba5a4fc51ceb379eb5269ff3 283 SMART SM00382 28 213 1.1E-10 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L08_07745 6f2a6537ba5a4fc51ceb379eb5269ff3 283 Pfam PF00005 ABC transporter 20 157 1.0E-27 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L08_07745 6f2a6537ba5a4fc51ceb379eb5269ff3 283 SUPERFAMILY SSF52540 2 221 6.76E-59 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_07745 6f2a6537ba5a4fc51ceb379eb5269ff3 283 ProSitePatterns PS00211 ABC transporters family signature. 130 144 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L08_07745 6f2a6537ba5a4fc51ceb379eb5269ff3 283 Gene3D G3DSA:3.40.50.300 1 233 4.2E-60 T 23-10-2018 A3L08_01040 8896047c6fd9b78e6bb12022353c0c09 153 SUPERFAMILY SSF55186 5 148 2.09E-35 T 23-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 A3L08_01040 8896047c6fd9b78e6bb12022353c0c09 153 Gene3D G3DSA:3.30.54.20 76 119 1.4E-20 T 23-10-2018 A3L08_01040 8896047c6fd9b78e6bb12022353c0c09 153 Gene3D G3DSA:3.30.980.10 2 75 4.8E-34 T 23-10-2018 A3L08_00235 f8338ecfe58d0504c4064bf35e65e007 70 Pfam PF01381 Helix-turn-helix 5 58 9.4E-21 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A3L08_00235 f8338ecfe58d0504c4064bf35e65e007 70 SUPERFAMILY SSF47413 3 67 7.24E-22 T 23-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A3L08_00235 f8338ecfe58d0504c4064bf35e65e007 70 Gene3D G3DSA:1.10.260.40 1 65 3.4E-32 T 23-10-2018 A3L08_00235 f8338ecfe58d0504c4064bf35e65e007 70 SMART SM00530 4 59 8.3E-22 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A3L08_07980 74199c5d4415b7e19d184d1f1c259992 248 SUPERFAMILY SSF52540 4 219 2.09E-60 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_07980 74199c5d4415b7e19d184d1f1c259992 248 SMART SM00382 28 211 1.2E-15 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L08_07980 74199c5d4415b7e19d184d1f1c259992 248 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L08_07980 74199c5d4415b7e19d184d1f1c259992 248 Pfam PF00005 ABC transporter 19 163 1.9E-28 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L08_07980 74199c5d4415b7e19d184d1f1c259992 248 Gene3D G3DSA:3.40.50.300 1 240 3.7E-65 T 23-10-2018 A3L08_07640 cda92c6d471f86e37bc84e45c2d4908f 416 SMART SM00471 48 188 2.1E-12 T 23-10-2018 IPR003607 HD/PDEase domain A3L08_07640 cda92c6d471f86e37bc84e45c2d4908f 416 SUPERFAMILY SSF109604 3 411 1.73E-88 T 23-10-2018 A3L08_07640 cda92c6d471f86e37bc84e45c2d4908f 416 Pfam PF01966 HD domain 52 179 5.9E-15 T 23-10-2018 IPR006674 HD domain A3L08_07640 cda92c6d471f86e37bc84e45c2d4908f 416 Gene3D G3DSA:1.10.3210.10 3 287 5.2E-84 T 23-10-2018 A3L08_03970 db71786b52c76c5b0df298589e9fb2ad 106 SUPERFAMILY SSF50447 23 103 1.94E-9 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily A3L08_03970 db71786b52c76c5b0df298589e9fb2ad 106 Gene3D G3DSA:2.40.30.10 17 106 1.9E-16 T 23-10-2018 A3L08_01000 3533988311618d88ac1a1f79b57a5d3e 338 SUPERFAMILY SSF81345 3 330 7.45E-78 T 23-10-2018 IPR037294 ABC transporter, BtuC-like A3L08_01000 3533988311618d88ac1a1f79b57a5d3e 338 Gene3D G3DSA:1.10.3470.10 2 335 8.1E-93 T 23-10-2018 IPR037294 ABC transporter, BtuC-like A3L08_01000 3533988311618d88ac1a1f79b57a5d3e 338 Pfam PF01032 FecCD transport family 13 330 1.7E-84 T 23-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 A3L08_06480 4b9edbf25d5a140dae5553643b9790ae 428 Gene3D G3DSA:1.10.645.10 6 424 2.2E-107 T 23-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L08_06480 4b9edbf25d5a140dae5553643b9790ae 428 ProSitePatterns PS00508 Nickel-dependent hydrogenases large subunit signature 2. 415 424 - T 23-10-2018 IPR018194 Nickel-dependent hydrogenase, large subunit, nickel binding site GO:0008901|GO:0016151|GO:0055114 A3L08_06480 4b9edbf25d5a140dae5553643b9790ae 428 SUPERFAMILY SSF56762 8 424 1.09E-97 T 23-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L08_06480 4b9edbf25d5a140dae5553643b9790ae 428 Pfam PF00374 Nickel-dependent hydrogenase 244 424 1.7E-12 T 23-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 A3L08_06480 4b9edbf25d5a140dae5553643b9790ae 428 Pfam PF00374 Nickel-dependent hydrogenase 43 121 1.6E-11 T 23-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 A3L08_07305 81d5e02da3b677a1476918c53a996b7a 212 Hamap MF_00052_A Ribonuclease HII [rnhB]. 1 189 29.788 T 23-10-2018 IPR020787 Ribonuclease HII, archaea GO:0004523|GO:0005737|GO:0006401|GO:0030145 A3L08_07305 81d5e02da3b677a1476918c53a996b7a 212 Pfam PF01351 Ribonuclease HII 1 183 9.0E-40 T 23-10-2018 IPR024567 Ribonuclease HII/HIII domain A3L08_07305 81d5e02da3b677a1476918c53a996b7a 212 Gene3D G3DSA:3.30.420.10 1 144 7.4E-47 T 23-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 A3L08_07305 81d5e02da3b677a1476918c53a996b7a 212 TIGRFAM TIGR00729 TIGR00729: ribonuclease HII 1 189 7.5E-65 T 23-10-2018 IPR004649 Ribonuclease H2, subunit A GO:0004523|GO:0016070 A3L08_07305 81d5e02da3b677a1476918c53a996b7a 212 Gene3D G3DSA:1.10.10.460 145 191 1.5E-25 T 23-10-2018 IPR023160 Ribonuclease HII, helix-loop-helix cap domain superfamily GO:0004523 A3L08_07305 81d5e02da3b677a1476918c53a996b7a 212 SUPERFAMILY SSF53098 1 192 1.67E-48 T 23-10-2018 IPR012337 Ribonuclease H-like superfamily A3L08_08240 457b0c96de566fc74302ba893102d483 171 Gene3D G3DSA:1.20.1260.10 2 132 6.9E-48 T 23-10-2018 IPR012347 Ferritin-like A3L08_08240 457b0c96de566fc74302ba893102d483 171 SUPERFAMILY SSF47240 3 132 3.66E-39 T 23-10-2018 IPR009078 Ferritin-like superfamily A3L08_08240 457b0c96de566fc74302ba893102d483 171 Gene3D G3DSA:2.20.28.10 133 171 2.6E-18 T 23-10-2018 A3L08_08240 457b0c96de566fc74302ba893102d483 171 SUPERFAMILY SSF57802 137 170 1.85E-10 T 23-10-2018 A3L08_08240 457b0c96de566fc74302ba893102d483 171 Pfam PF02915 Rubrerythrin 10 124 1.7E-26 T 23-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 A3L08_03960 f35673741aa44f64b0c218b857dcf9d8 92 Gene3D G3DSA:3.30.460.10 1 83 2.1E-18 T 23-10-2018 A3L08_03960 f35673741aa44f64b0c218b857dcf9d8 92 Pfam PF01909 Nucleotidyltransferase domain 2 80 1.7E-12 T 23-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 A3L08_03960 f35673741aa44f64b0c218b857dcf9d8 92 SUPERFAMILY SSF81301 1 88 5.84E-21 T 23-10-2018 A3L08_09250 e643d4420221f5bfd010a4a90a789734 241 Gene3D G3DSA:2.40.50.580 5 81 2.0E-25 T 23-10-2018 A3L08_09250 e643d4420221f5bfd010a4a90a789734 241 Hamap MF_00095 Sugar fermentation stimulation protein A [sfsA]. 6 236 38.579 T 23-10-2018 IPR005224 Sugar fermentation stimulation protein A3L08_09250 e643d4420221f5bfd010a4a90a789734 241 Pfam PF03749 Sugar fermentation stimulation protein 17 223 1.5E-48 T 23-10-2018 IPR005224 Sugar fermentation stimulation protein A3L08_09250 e643d4420221f5bfd010a4a90a789734 241 TIGRFAM TIGR00230 sfsA: sugar fermentation stimulation protein 10 235 4.2E-52 T 23-10-2018 IPR005224 Sugar fermentation stimulation protein A3L08_09250 e643d4420221f5bfd010a4a90a789734 241 Gene3D G3DSA:3.40.1350.60 82 236 2.7E-41 T 23-10-2018 A3L08_06400 72d28f4c8c72bfc9c0faefe7505b2731 350 SUPERFAMILY SSF75217 186 336 6.54E-18 T 23-10-2018 IPR029028 Alpha/beta knot methyltransferases A3L08_06400 72d28f4c8c72bfc9c0faefe7505b2731 350 SUPERFAMILY SSF143437 3 147 3.01E-27 T 23-10-2018 A3L08_06400 72d28f4c8c72bfc9c0faefe7505b2731 350 SMART SM00981 60 149 5.6E-24 T 23-10-2018 IPR004114 THUMP domain GO:0003723 A3L08_06400 72d28f4c8c72bfc9c0faefe7505b2731 350 Pfam PF02926 THUMP domain 25 149 2.2E-29 T 23-10-2018 IPR004114 THUMP domain GO:0003723 A3L08_06400 72d28f4c8c72bfc9c0faefe7505b2731 350 Gene3D G3DSA:3.30.2130.30 1 149 5.4E-23 T 23-10-2018 A3L08_06400 72d28f4c8c72bfc9c0faefe7505b2731 350 Pfam PF14419 AF2226-like SPOUT RNA Methylase fused to THUMP 169 342 4.0E-81 T 23-10-2018 IPR025849 AF2226-like SPOUT RNA methylase fused to THUMP A3L08_06235 79815999c09eee8a2f9b8a8826fd40d1 166 SUPERFAMILY SSF55021 105 164 1.06E-8 T 23-10-2018 A3L08_06235 79815999c09eee8a2f9b8a8826fd40d1 166 Pfam PF01842 ACT domain 105 158 6.3E-7 T 23-10-2018 IPR002912 ACT domain A3L08_06235 79815999c09eee8a2f9b8a8826fd40d1 166 PIRSF PIRSF004897 1 166 3.0E-70 T 23-10-2018 IPR014424 Uncharacterised conserved protein UCP004897, ACT- type A3L08_03965 b5c70c1739b47a17f7d0b9c7362897ed 281 ProDom PD038341 HYDROLASE COFACTOR MOLYBDENUM BIOSYNTHESIS METAL-DEPENDENT DEOXYRIBONUCLEASE PREDICTED TATD-RELATED TVG0313409 A 114 280 7.0E-82 T 23-10-2018 A3L08_03965 b5c70c1739b47a17f7d0b9c7362897ed 281 Gene3D G3DSA:3.20.20.140 3 280 7.9E-27 T 23-10-2018 A3L08_03965 b5c70c1739b47a17f7d0b9c7362897ed 281 Pfam PF01026 TatD related DNase 5 275 3.7E-30 T 23-10-2018 IPR001130 TatD family GO:0016788 A3L08_03965 b5c70c1739b47a17f7d0b9c7362897ed 281 PIRSF PIRSF004961 1 281 9.6E-122 T 23-10-2018 IPR011589 Protein of unknown function UCP004961 A3L08_03965 b5c70c1739b47a17f7d0b9c7362897ed 281 SUPERFAMILY SSF51556 1 278 2.51E-32 T 23-10-2018 IPR032466 Metal-dependent hydrolase A3L08_03615 a3f9727be7844840c96015feb493851f 271 SUPERFAMILY SSF50249 35 131 1.83E-11 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L08_03615 a3f9727be7844840c96015feb493851f 271 Pfam PF01336 OB-fold nucleic acid binding domain 56 115 9.4E-9 T 23-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 A3L08_03615 a3f9727be7844840c96015feb493851f 271 Gene3D G3DSA:2.40.50.140 21 140 1.2E-14 T 23-10-2018 A3L08_03870 c88d5663c51bc70c66333987405b6a9c 134 PIRSF PIRSF019313 1 134 5.6E-31 T 23-10-2018 IPR012426 Uncharacterised protein family SepF-related, archaea A3L08_03870 c88d5663c51bc70c66333987405b6a9c 134 Gene3D G3DSA:3.30.110.150 50 134 8.5E-26 T 23-10-2018 IPR038594 SepF-like superfamily A3L08_03870 c88d5663c51bc70c66333987405b6a9c 134 Pfam PF04472 Cell division protein SepF 60 132 2.5E-14 T 23-10-2018 IPR007561 Cell division protein SepF/SepF-related GO:0090529 A3L08_05570 196e4f7ae47fb6bd218b36e224973326 221 Gene3D G3DSA:3.40.50.300 1 208 3.3E-52 T 23-10-2018 A3L08_03520 919b777b0e121e717e70087d29ff17d2 448 PRINTS PR01874 DNA repair protein radA signature 13 41 1.5E-10 T 23-10-2018 A3L08_03520 919b777b0e121e717e70087d29ff17d2 448 PRINTS PR01874 DNA repair protein radA signature 154 182 1.5E-10 T 23-10-2018 A3L08_03520 919b777b0e121e717e70087d29ff17d2 448 Gene3D G3DSA:3.40.50.300 226 448 1.9E-48 T 23-10-2018 A3L08_03520 919b777b0e121e717e70087d29ff17d2 448 SMART SM00382 255 405 5.5E-9 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L08_03520 919b777b0e121e717e70087d29ff17d2 448 SMART SM00382 21 152 0.21 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L08_03520 919b777b0e121e717e70087d29ff17d2 448 SUPERFAMILY SSF52540 2 229 2.6E-39 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_03520 919b777b0e121e717e70087d29ff17d2 448 Pfam PF06745 KaiC 4 222 2.4E-46 T 23-10-2018 IPR014774 KaiC-like domain A3L08_03520 919b777b0e121e717e70087d29ff17d2 448 Pfam PF06745 KaiC 238 447 1.5E-28 T 23-10-2018 IPR014774 KaiC-like domain A3L08_03520 919b777b0e121e717e70087d29ff17d2 448 Gene3D G3DSA:3.40.50.300 1 225 6.7E-51 T 23-10-2018 A3L08_03520 919b777b0e121e717e70087d29ff17d2 448 PIRSF PIRSF039117 1 448 2.5E-112 T 23-10-2018 IPR030665 Circadian clock protein kinase KaiC KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1 A3L08_03520 919b777b0e121e717e70087d29ff17d2 448 SUPERFAMILY SSF52540 232 447 4.91E-37 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_08050 a8b3b1eceabb0e3d74d8245316b72158 377 Pfam PF07728 AAA domain (dynein-related subfamily) 132 282 2.9E-18 T 23-10-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 A3L08_08050 a8b3b1eceabb0e3d74d8245316b72158 377 SUPERFAMILY SSF52540 111 315 9.71E-21 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_08050 a8b3b1eceabb0e3d74d8245316b72158 377 Gene3D G3DSA:3.40.50.300 115 296 4.8E-28 T 23-10-2018 A3L08_08050 a8b3b1eceabb0e3d74d8245316b72158 377 SMART SM00382 128 290 0.0011 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L08_01615 c4776aba7f2d797e5774fc5a0eb93e64 122 Pfam PF03625 Domain of unknown function DUF302 35 92 1.9E-14 T 23-10-2018 IPR005180 Domain of unknown function DUF302 A3L08_01615 c4776aba7f2d797e5774fc5a0eb93e64 122 SUPERFAMILY SSF103247 9 117 3.4E-23 T 23-10-2018 IPR035923 TT1751-like domain superfamily A3L08_01615 c4776aba7f2d797e5774fc5a0eb93e64 122 Gene3D G3DSA:3.30.310.70 2 121 1.3E-25 T 23-10-2018 IPR035923 TT1751-like domain superfamily A3L08_07735 64c7cd7c12b280c6cf39cece62497e14 218 SUPERFAMILY SSF88659 161 214 2.31E-5 T 23-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A3L08_07735 64c7cd7c12b280c6cf39cece62497e14 218 Pfam PF04967 HTH DNA binding domain 162 213 2.1E-19 T 23-10-2018 IPR007050 Bacterioopsin activator-type, HTH domain A3L08_07735 64c7cd7c12b280c6cf39cece62497e14 218 Gene3D G3DSA:1.10.10.10 150 217 4.6E-6 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L08_01340 43a783abac714042e9d3e24e218c141b 297 Gene3D G3DSA:3.40.50.300 17 281 6.8E-82 T 23-10-2018 A3L08_01340 43a783abac714042e9d3e24e218c141b 297 Hamap MF_02040 Iron-sulfur cluster carrier protein. 20 282 37.184 T 23-10-2018 IPR019591 Mrp/NBP35 ATP-binding protein A3L08_01340 43a783abac714042e9d3e24e218c141b 297 SUPERFAMILY SSF52540 20 266 6.13E-59 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_01340 43a783abac714042e9d3e24e218c141b 297 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 30 281 3.4E-96 T 23-10-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 A3L08_01340 43a783abac714042e9d3e24e218c141b 297 ProSitePatterns PS01215 Mrp family signature. 146 162 - T 23-10-2018 IPR000808 Mrp, conserved site GO:0005524 A3L08_07180 f2de4d0f75d611f86c016f85b9a527e9 76 Hamap MF_00257 Putative snRNP Sm-like protein. 1 72 25.31 T 23-10-2018 IPR022901 snRNP Sm-like, putative, archaea A3L08_07180 f2de4d0f75d611f86c016f85b9a527e9 76 Gene3D G3DSA:2.30.30.100 1 74 1.9E-22 T 23-10-2018 A3L08_07180 f2de4d0f75d611f86c016f85b9a527e9 76 SUPERFAMILY SSF50182 5 74 5.54E-17 T 23-10-2018 IPR010920 LSM domain superfamily A3L08_07180 f2de4d0f75d611f86c016f85b9a527e9 76 Pfam PF01423 LSM domain 9 72 1.9E-18 T 23-10-2018 IPR001163 LSM domain, eukaryotic/archaea-type A3L08_07180 f2de4d0f75d611f86c016f85b9a527e9 76 SMART SM00651 7 72 4.6E-20 T 23-10-2018 IPR001163 LSM domain, eukaryotic/archaea-type A3L08_05520 61a8edc0c311ee7b884ccd9e9aaee6cf 286 SMART SM00382 30 227 9.3E-14 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L08_05520 61a8edc0c311ee7b884ccd9e9aaee6cf 286 Gene3D G3DSA:3.40.50.300 2 272 4.6E-72 T 23-10-2018 A3L08_05520 61a8edc0c311ee7b884ccd9e9aaee6cf 286 SUPERFAMILY SSF52540 3 240 4.77E-59 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_05520 61a8edc0c311ee7b884ccd9e9aaee6cf 286 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L08_05520 61a8edc0c311ee7b884ccd9e9aaee6cf 286 Pfam PF00005 ABC transporter 21 178 4.4E-25 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L08_03170 1f8377c16943f2bd97088f36bd1f5c71 355 SUPERFAMILY SSF53067 1 310 4.12E-8 T 23-10-2018 A3L08_03170 1f8377c16943f2bd97088f36bd1f5c71 355 PIRSF PIRSF009433 1 354 1.3E-143 T 23-10-2018 IPR009927 Protein of unknown function DUF1464 A3L08_03170 1f8377c16943f2bd97088f36bd1f5c71 355 Pfam PF07318 Protein of unknown function (DUF1464) 5 350 1.5E-132 T 23-10-2018 IPR009927 Protein of unknown function DUF1464 A3L08_09200 f3c44e7b3e94cf40d9bcb8524b5d85b1 253 Gene3D G3DSA:3.20.20.390 4 252 8.1E-100 T 23-10-2018 IPR038597 GGGP/HepGP synthase superfamily A3L08_09200 f3c44e7b3e94cf40d9bcb8524b5d85b1 253 Pfam PF01884 PcrB family 17 238 1.7E-67 T 23-10-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 A3L08_09200 f3c44e7b3e94cf40d9bcb8524b5d85b1 253 SUPERFAMILY SSF51395 20 235 2.23E-47 T 23-10-2018 A3L08_09200 f3c44e7b3e94cf40d9bcb8524b5d85b1 253 TIGRFAM TIGR01768 GGGP-family: geranylgeranylglyceryl phosphate synthase family protein 21 242 1.4E-79 T 23-10-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 A3L08_09200 f3c44e7b3e94cf40d9bcb8524b5d85b1 253 TIGRFAM TIGR01769 GGGP: phosphoglycerol geranylgeranyltransferase 22 228 1.0E-83 T 23-10-2018 IPR010946 Geranylgeranylglyceryl phosphate synthase GO:0000287|GO:0005737|GO:0006650|GO:0047294 KEGG: 00564+2.5.1.41|MetaCyc: PWY-6349 A3L08_09200 f3c44e7b3e94cf40d9bcb8524b5d85b1 253 Hamap MF_00112 Geranylgeranylglyceryl phosphate synthase [pcrB]. 15 247 35.553 T 23-10-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 A3L08_08430 650438c6749aa706edf32717032edc2d 584 Pfam PF13722 5TM C-terminal transporter carbon starvation CstA 409 532 8.5E-33 T 23-10-2018 IPR025299 CstA, C-terminal domain A3L08_08430 650438c6749aa706edf32717032edc2d 584 Pfam PF02554 Carbon starvation protein CstA 1 366 1.1E-107 T 23-10-2018 IPR003706 CstA, N-terminal domain GO:0009267|GO:0016020 A3L08_04050 0811093682cc3a49218dcc4ce83e272f 255 ProSitePatterns PS00939 Ribosomal protein L1e signature. 106 132 - T 23-10-2018 IPR013000 Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_04050 0811093682cc3a49218dcc4ce83e272f 255 Gene3D G3DSA:3.40.1370.10 1 255 6.7E-100 T 23-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 A3L08_04050 0811093682cc3a49218dcc4ce83e272f 255 TIGRFAM TIGR03672 rpl4p_arch: 50S ribosomal protein uL4 1 252 2.6E-117 T 23-10-2018 IPR019970 Ribosomal protein L4 GO:0003735|GO:0005840|GO:0006412|GO:0019843 A3L08_04050 0811093682cc3a49218dcc4ce83e272f 255 Pfam PF00573 Ribosomal protein L4/L1 family 16 252 3.2E-49 T 23-10-2018 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 A3L08_04050 0811093682cc3a49218dcc4ce83e272f 255 Hamap MF_01328_A 50S ribosomal protein L4 [rplD]. 2 253 44.483 T 23-10-2018 IPR019970 Ribosomal protein L4 GO:0003735|GO:0005840|GO:0006412|GO:0019843 A3L08_04050 0811093682cc3a49218dcc4ce83e272f 255 SUPERFAMILY SSF52166 1 252 3.27E-73 T 23-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 A3L08_07365 fbfcd2a005b57b63a01b85228891b13b 268 Pfam PF02649 Type I GTP cyclohydrolase folE2 5 264 7.3E-66 T 23-10-2018 IPR003801 GTP cyclohydrolase FolE2/MptA GO:0003933 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852 A3L08_07365 fbfcd2a005b57b63a01b85228891b13b 268 Hamap MF_01527_A GTP cyclohydrolase FolE2 [folE2]. 2 268 26.824 T 23-10-2018 IPR022840 GTP cyclohydrolase MptA GO:0003933 KEGG: 00790+3.5.4.39|MetaCyc: PWY-6797|MetaCyc: PWY-7853 A3L08_07365 fbfcd2a005b57b63a01b85228891b13b 268 Gene3D G3DSA:3.10.270.10 3 267 7.9E-67 T 23-10-2018 A3L08_03060 dba214527341239c88005d651243f442 287 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 112 140 - T 23-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A3L08_03060 dba214527341239c88005d651243f442 287 Gene3D G3DSA:3.90.25.10 164 277 1.1E-94 T 23-10-2018 A3L08_03060 dba214527341239c88005d651243f442 287 TIGRFAM TIGR01214 rmlD: dTDP-4-dehydrorhamnose reductase 2 282 4.4E-109 T 23-10-2018 IPR005913 dTDP-4-dehydrorhamnose reductase family Reactome: R-HSA-156581|Reactome: R-HSA-5689880 A3L08_03060 dba214527341239c88005d651243f442 287 SUPERFAMILY SSF51735 2 283 9.06E-83 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L08_03060 dba214527341239c88005d651243f442 287 Gene3D G3DSA:3.40.50.720 3 271 1.1E-94 T 23-10-2018 A3L08_03060 dba214527341239c88005d651243f442 287 Pfam PF04321 RmlD substrate binding domain 2 283 1.5E-84 T 23-10-2018 IPR029903 RmlD-like substrate binding domain Reactome: R-HSA-156581|Reactome: R-HSA-5689880 A3L08_02535 3d4b3fb646fc7b9c210040772fe31808 168 Gene3D G3DSA:3.10.450.220 1 94 7.3E-44 T 23-10-2018 A3L08_02535 3d4b3fb646fc7b9c210040772fe31808 168 Pfam PF03657 Uncharacterised protein family (UPF0113) 6 166 9.1E-11 T 23-10-2018 IPR005155 Ribosome biogenesis factor NIP7-like Reactome: R-HSA-6791226 A3L08_02535 3d4b3fb646fc7b9c210040772fe31808 168 Gene3D G3DSA:2.30.130.10 95 166 3.4E-19 T 23-10-2018 IPR036974 PUA domain superfamily GO:0003723 A3L08_09370 d1d51a87c3dd963df719be0902a86eff 247 Gene3D G3DSA:3.40.50.300 1 243 3.3E-57 T 23-10-2018 A3L08_09370 d1d51a87c3dd963df719be0902a86eff 247 Pfam PF03029 Conserved hypothetical ATP binding protein 6 241 9.8E-51 T 23-10-2018 IPR004130 GPN-loop GTPase A3L08_09370 d1d51a87c3dd963df719be0902a86eff 247 SUPERFAMILY SSF52540 1 239 4.62E-37 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_09620 8d2d250eb7375ff0a56c2c928245eaea 157 Gene3D G3DSA:3.30.460.40 1 156 1.3E-54 T 23-10-2018 A3L08_09620 8d2d250eb7375ff0a56c2c928245eaea 157 SUPERFAMILY SSF81301 1 153 1.08E-39 T 23-10-2018 A3L08_09695 e7a75cc85c1638f3409044970b572e2b 259 SUPERFAMILY SSF101852 163 254 6.28E-25 T 23-10-2018 IPR023227 S-adenosyl-l-methionine hydroxide adenosyltransferase, C-terminal A3L08_09695 e7a75cc85c1638f3409044970b572e2b 259 Pfam PF01887 S-adenosyl-l-methionine hydroxide adenosyltransferase 2 252 4.8E-78 T 23-10-2018 IPR002747 SAM-dependent chlorinase/fluorinase A3L08_09695 e7a75cc85c1638f3409044970b572e2b 259 SUPERFAMILY SSF102522 1 161 4.71E-56 T 23-10-2018 IPR023228 S-adenosyl-l-methionine hydroxide adenosyltransferase, N-terminal A3L08_09695 e7a75cc85c1638f3409044970b572e2b 259 Gene3D G3DSA:2.40.30.90 161 256 2.4E-34 T 23-10-2018 IPR023227 S-adenosyl-l-methionine hydroxide adenosyltransferase, C-terminal A3L08_09695 e7a75cc85c1638f3409044970b572e2b 259 Gene3D G3DSA:3.40.50.10790 1 160 1.4E-61 T 23-10-2018 IPR023228 S-adenosyl-l-methionine hydroxide adenosyltransferase, N-terminal A3L08_09695 e7a75cc85c1638f3409044970b572e2b 259 PIRSF PIRSF006779 1 256 1.4E-77 T 23-10-2018 IPR002747 SAM-dependent chlorinase/fluorinase A3L08_09290 8e8137a045e68e7c21bb57051f2a32a5 183 Pfam PF06197 Protein of unknown function (DUF998) 14 176 1.3E-14 T 23-10-2018 IPR009339 Protein of unknown function DUF998 A3L08_01915 e4b482ec04914fca58b10859416cf1e0 310 SUPERFAMILY SSF102114 136 286 9.02E-11 T 23-10-2018 A3L08_01915 e4b482ec04914fca58b10859416cf1e0 310 Pfam PF13186 Iron-sulfur cluster-binding domain 225 281 1.8E-5 T 23-10-2018 IPR023885 4Fe4S-binding SPASM domain A3L08_01915 e4b482ec04914fca58b10859416cf1e0 310 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 222 302 1.4E-8 T 23-10-2018 IPR023885 4Fe4S-binding SPASM domain A3L08_01915 e4b482ec04914fca58b10859416cf1e0 310 Gene3D G3DSA:3.20.20.70 187 309 1.5E-9 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L08_09360 2f57c92805b92a9cefff07485c9da8f2 602 Gene3D G3DSA:3.40.50.1010 1 127 1.9E-33 T 23-10-2018 A3L08_09360 2f57c92805b92a9cefff07485c9da8f2 602 Pfam PF00437 Type II/IV secretion system protein 213 370 1.4E-9 T 23-10-2018 IPR001482 Type II/IV secretion system protein A3L08_09360 2f57c92805b92a9cefff07485c9da8f2 602 SUPERFAMILY SSF52540 133 438 7.64E-29 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_09360 2f57c92805b92a9cefff07485c9da8f2 602 Gene3D G3DSA:3.40.50.300 239 426 2.4E-17 T 23-10-2018 A3L08_09360 2f57c92805b92a9cefff07485c9da8f2 602 SMART SM00670 2 115 2.4E-21 T 23-10-2018 IPR002716 PIN domain A3L08_09360 2f57c92805b92a9cefff07485c9da8f2 602 SUPERFAMILY SSF54814 466 521 6.28E-6 T 23-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 A3L08_09360 2f57c92805b92a9cefff07485c9da8f2 602 SUPERFAMILY SSF88723 1 131 6.17E-17 T 23-10-2018 IPR029060 PIN-like domain superfamily A3L08_02400 ddf37558ffbc0d66555f730932756c74 459 Gene3D G3DSA:2.60.40.1190 247 453 5.3E-5 T 23-10-2018 A3L08_02400 ddf37558ffbc0d66555f730932756c74 459 SUPERFAMILY SSF49344 252 409 6.28E-13 T 23-10-2018 A3L08_08540 e4879c98c0c8d28f1895109d96df7e1f 187 Pfam PF06197 Protein of unknown function (DUF998) 10 181 1.5E-29 T 23-10-2018 IPR009339 Protein of unknown function DUF998 A3L08_06010 540ebd43e8417584277f8c70cc97ddcc 117 TIGRFAM TIGR02338 gimC_beta: prefoldin, beta subunit 4 112 4.2E-40 T 23-10-2018 IPR012713 Prefoldin subunit beta GO:0006457|GO:0016272|GO:0051082 A3L08_06010 540ebd43e8417584277f8c70cc97ddcc 117 SUPERFAMILY SSF46579 6 110 1.1E-22 T 23-10-2018 A3L08_06010 540ebd43e8417584277f8c70cc97ddcc 117 Hamap MF_00307 Prefoldin subunit beta [pfdB]. 1 117 50.474 T 23-10-2018 IPR012713 Prefoldin subunit beta GO:0006457|GO:0016272|GO:0051082 A3L08_06010 540ebd43e8417584277f8c70cc97ddcc 117 Gene3D G3DSA:1.10.287.370 1 117 1.0E-40 T 23-10-2018 IPR009053 Prefoldin A3L08_06010 540ebd43e8417584277f8c70cc97ddcc 117 Pfam PF01920 Prefoldin subunit 9 111 3.2E-24 T 23-10-2018 IPR002777 Prefoldin beta-like GO:0006457|GO:0016272|GO:0051082 Reactome: R-HSA-389957 A3L08_05860 a96ef648e4ff68950e0111721236ce17 245 Hamap MF_01408 Flavin-dependent thymidylate synthase [thyX]. 5 219 30.789 T 23-10-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 A3L08_05860 a96ef648e4ff68950e0111721236ce17 245 Pfam PF02511 Thymidylate synthase complementing protein 8 198 1.8E-63 T 23-10-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 A3L08_05860 a96ef648e4ff68950e0111721236ce17 245 Gene3D G3DSA:3.30.1360.170 1 202 2.5E-64 T 23-10-2018 A3L08_05860 a96ef648e4ff68950e0111721236ce17 245 TIGRFAM TIGR02170 thyX: thymidylate synthase, flavin-dependent 6 199 6.9E-54 T 23-10-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 A3L08_05860 a96ef648e4ff68950e0111721236ce17 245 SUPERFAMILY SSF69796 3 198 1.31E-60 T 23-10-2018 IPR036098 Thymidylate synthase ThyX superfamily GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 A3L08_03330 31685d8e732778cc06069a496b91d7b1 191 Pfam PF04021 Class III signal peptide 5 26 9.1E-6 T 23-10-2018 IPR007166 Class III signal peptide motif A3L08_01910 bc627b5bc49c8cc1401ae71caed1742e 305 Pfam PF13412 Winged helix-turn-helix DNA-binding 156 195 8.8E-12 T 23-10-2018 A3L08_01910 bc627b5bc49c8cc1401ae71caed1742e 305 SMART SM00344 155 247 0.0015 T 23-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A3L08_01910 bc627b5bc49c8cc1401ae71caed1742e 305 Gene3D G3DSA:1.10.10.10 152 198 1.2E-12 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L08_01910 bc627b5bc49c8cc1401ae71caed1742e 305 SUPERFAMILY SSF46785 151 201 3.74E-9 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L08_06100 bd915e6aa02bc6c93e09b5faa3f81a39 153 Pfam PF10050 Predicted metal-binding protein (DUF2284) 8 138 2.9E-33 T 23-10-2018 IPR019271 Protein of unknown function DUF2284, metal-binding A3L08_06100 bd915e6aa02bc6c93e09b5faa3f81a39 153 PIRSF PIRSF018748 1 153 1.3E-53 T 23-10-2018 IPR019271 Protein of unknown function DUF2284, metal-binding A3L08_09600 1933dbc6d1fbf6c4026fcb6868ea09ec 150 SMART SM00195 4 146 1.4E-9 T 23-10-2018 IPR020422 Dual specificity protein phosphatase domain GO:0006470|GO:0008138 A3L08_09600 1933dbc6d1fbf6c4026fcb6868ea09ec 150 ProSitePatterns PS00383 Tyrosine specific protein phosphatases active site. 91 101 - T 23-10-2018 IPR016130 Protein-tyrosine phosphatase, active site GO:0004725|GO:0016311 A3L08_09600 1933dbc6d1fbf6c4026fcb6868ea09ec 150 SUPERFAMILY SSF52799 29 148 9.25E-36 T 23-10-2018 IPR029021 Protein-tyrosine phosphatase-like A3L08_09600 1933dbc6d1fbf6c4026fcb6868ea09ec 150 SMART SM00404 52 146 3.2E-5 T 23-10-2018 IPR003595 Protein-tyrosine phosphatase, catalytic A3L08_09600 1933dbc6d1fbf6c4026fcb6868ea09ec 150 Pfam PF00782 Dual specificity phosphatase, catalytic domain 50 144 1.2E-17 T 23-10-2018 IPR000340 Dual specificity phosphatase, catalytic domain GO:0008138|GO:0016311 A3L08_09600 1933dbc6d1fbf6c4026fcb6868ea09ec 150 Gene3D G3DSA:3.90.190.10 6 149 9.6E-35 T 23-10-2018 IPR029021 Protein-tyrosine phosphatase-like A3L08_03725 a8b7829c057edaac3703368cfdcb712b 334 SUPERFAMILY SSF48150 199 315 3.77E-8 T 23-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 A3L08_02615 fe7c32a3c3e9d995745028203a011003 408 Gene3D G3DSA:3.10.310.40 302 405 9.7E-9 T 23-10-2018 A3L08_02615 fe7c32a3c3e9d995745028203a011003 408 SUPERFAMILY SSF55186 95 241 2.35E-37 T 23-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 A3L08_02615 fe7c32a3c3e9d995745028203a011003 408 SUPERFAMILY SSF50447 1 91 3.04E-15 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily A3L08_02615 fe7c32a3c3e9d995745028203a011003 408 Gene3D G3DSA:3.30.980.10 92 248 2.9E-42 T 23-10-2018 A3L08_02615 fe7c32a3c3e9d995745028203a011003 408 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 191 234 1.7E-10 T 23-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 A3L08_02615 fe7c32a3c3e9d995745028203a011003 408 Gene3D G3DSA:2.40.30.130 1 91 2.5E-19 T 23-10-2018 A3L08_02615 fe7c32a3c3e9d995745028203a011003 408 SMART SM00863 191 234 6.9E-15 T 23-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 A3L08_02615 fe7c32a3c3e9d995745028203a011003 408 Pfam PF01411 tRNA synthetases class II (A) 24 94 1.5E-11 T 23-10-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 A3L08_02615 fe7c32a3c3e9d995745028203a011003 408 Pfam PF02272 DHHA1 domain 270 400 2.2E-11 T 23-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 A3L08_09795 60fc63291f32ea3f00afc3bcbfc53837 124 Gene3D G3DSA:2.30.30.110 22 124 1.8E-19 T 23-10-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor A3L08_09795 60fc63291f32ea3f00afc3bcbfc53837 124 SUPERFAMILY SSF50118 12 123 6.54E-18 T 23-10-2018 A3L08_09795 60fc63291f32ea3f00afc3bcbfc53837 124 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 13 123 4.1E-19 T 23-10-2018 IPR003477 mRNA interferase PemK-like GO:0003677 A3L08_08235 96ad726050d224aaae441a45f4406cfc 361 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 3 22 1.5E-20 T 23-10-2018 A3L08_08235 96ad726050d224aaae441a45f4406cfc 361 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 94 112 1.5E-20 T 23-10-2018 A3L08_08235 96ad726050d224aaae441a45f4406cfc 361 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 137 155 1.5E-20 T 23-10-2018 A3L08_08235 96ad726050d224aaae441a45f4406cfc 361 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 240 262 1.5E-20 T 23-10-2018 A3L08_08235 96ad726050d224aaae441a45f4406cfc 361 SUPERFAMILY SSF51905 1 172 1.23E-36 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L08_08235 96ad726050d224aaae441a45f4406cfc 361 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 1 276 2.6E-53 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A3L08_08235 96ad726050d224aaae441a45f4406cfc 361 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 250 268 2.5E-8 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A3L08_08235 96ad726050d224aaae441a45f4406cfc 361 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 95 103 2.5E-8 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A3L08_08235 96ad726050d224aaae441a45f4406cfc 361 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 2 24 2.5E-8 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A3L08_08235 96ad726050d224aaae441a45f4406cfc 361 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 133 157 2.5E-8 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A3L08_08235 96ad726050d224aaae441a45f4406cfc 361 SUPERFAMILY SSF55424 290 351 9.89E-24 T 23-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 A3L08_08235 96ad726050d224aaae441a45f4406cfc 361 Gene3D G3DSA:3.50.50.60 3 276 2.3E-98 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L08_08235 96ad726050d224aaae441a45f4406cfc 361 SUPERFAMILY SSF51905 114 287 8.87E-26 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L08_08235 96ad726050d224aaae441a45f4406cfc 361 Gene3D G3DSA:3.50.50.60 106 223 2.3E-98 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L08_08235 96ad726050d224aaae441a45f4406cfc 361 Gene3D G3DSA:3.30.390.30 299 357 2.7E-25 T 23-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 A3L08_04445 86530f56abbc55893278b8d63920bf33 536 Gene3D G3DSA:3.10.310.70 84 199 3.5E-162 T 23-10-2018 A3L08_04445 86530f56abbc55893278b8d63920bf33 536 SUPERFAMILY SSF51556 65 497 2.5E-46 T 23-10-2018 IPR032466 Metal-dependent hydrolase A3L08_04445 86530f56abbc55893278b8d63920bf33 536 Gene3D G3DSA:3.20.20.140 66 496 3.5E-162 T 23-10-2018 A3L08_04445 86530f56abbc55893278b8d63920bf33 536 Gene3D G3DSA:2.30.40.10 11 514 3.5E-162 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A3L08_04445 86530f56abbc55893278b8d63920bf33 536 SUPERFAMILY SSF51338 10 536 2.47E-15 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A3L08_04445 86530f56abbc55893278b8d63920bf33 536 Pfam PF07969 Amidohydrolase family 54 535 2.2E-129 T 23-10-2018 IPR013108 Amidohydrolase 3 A3L08_06770 532d212fb84eae6a83fec11a6d99202d 170 SUPERFAMILY SSF53323 2 167 2.35E-42 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 A3L08_06770 532d212fb84eae6a83fec11a6d99202d 170 Gene3D G3DSA:3.40.920.10 1 170 5.6E-54 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 A3L08_06770 532d212fb84eae6a83fec11a6d99202d 170 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 9 166 7.8E-38 T 23-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 A3L08_07610 1d1fd203531ccf4f839e0cf36bfcc4b7 336 TIGRFAM TIGR00321 dhys: deoxyhypusine synthase 20 334 4.5E-121 T 23-10-2018 IPR002773 Deoxyhypusine synthase GO:0008612 Reactome: R-HSA-204626 A3L08_07610 1d1fd203531ccf4f839e0cf36bfcc4b7 336 Pfam PF01916 Deoxyhypusine synthase 34 331 3.7E-112 T 23-10-2018 IPR002773 Deoxyhypusine synthase GO:0008612 Reactome: R-HSA-204626 A3L08_07610 1d1fd203531ccf4f839e0cf36bfcc4b7 336 Gene3D G3DSA:3.40.910.10 2 336 1.6E-145 T 23-10-2018 IPR036982 Deoxyhypusine synthase superfamily GO:0008612 Reactome: R-HSA-204626 A3L08_07610 1d1fd203531ccf4f839e0cf36bfcc4b7 336 SUPERFAMILY SSF52467 5 334 3.24E-116 T 23-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily A3L08_07610 1d1fd203531ccf4f839e0cf36bfcc4b7 336 Hamap MF_00153 Probable deoxyhypusine synthase [dys]. 31 334 42.549 T 23-10-2018 IPR022899 Deoxyhypusine synthase, putative, archaeal GO:0034038 A3L08_03775 f669d7c152695ac3ba61fc633f2b06c0 394 SUPERFAMILY SSF103473 12 391 2.75E-56 T 23-10-2018 IPR036259 MFS transporter superfamily A3L08_03775 f669d7c152695ac3ba61fc633f2b06c0 394 Gene3D G3DSA:1.20.1250.20 209 394 1.6E-22 T 23-10-2018 A3L08_03775 f669d7c152695ac3ba61fc633f2b06c0 394 Pfam PF07690 Major Facilitator Superfamily 19 263 1.6E-24 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A3L08_03775 f669d7c152695ac3ba61fc633f2b06c0 394 Gene3D G3DSA:1.20.1250.20 12 207 1.4E-23 T 23-10-2018 A3L08_02545 16a63adb303e4f45469e0c313dcd4c64 167 Gene3D G3DSA:1.10.10.60 55 83 2.5E-5 T 23-10-2018 A3L08_02545 16a63adb303e4f45469e0c313dcd4c64 167 TIGRFAM TIGR03879 near_KaiC_dom: probable regulatory domain 29 101 4.4E-26 T 23-10-2018 IPR022285 Conserved hypothetical protein CHP03879, regulatory domain, putative A3L08_03990 1d1ba9431b2ac1f46094befc3c658a8a 154 TIGRFAM TIGR01958 nuoE_fam: NADH-quinone oxidoreductase, E subunit 8 147 6.4E-44 T 23-10-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L08_03990 1d1ba9431b2ac1f46094befc3c658a8a 154 Gene3D G3DSA:3.40.30.10 66 153 2.9E-32 T 23-10-2018 A3L08_03990 1d1ba9431b2ac1f46094befc3c658a8a 154 PIRSF PIRSF000216 3 154 9.0E-61 T 23-10-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L08_03990 1d1ba9431b2ac1f46094befc3c658a8a 154 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 7 147 1.5E-54 T 23-10-2018 A3L08_03990 1d1ba9431b2ac1f46094befc3c658a8a 154 ProSitePatterns PS01099 Respiratory-chain NADH dehydrogenase 24 Kd subunit signature. 105 123 - T 23-10-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L08_03990 1d1ba9431b2ac1f46094befc3c658a8a 154 SUPERFAMILY SSF52833 7 151 1.23E-53 T 23-10-2018 IPR036249 Thioredoxin-like superfamily A3L08_03990 1d1ba9431b2ac1f46094befc3c658a8a 154 Gene3D G3DSA:1.10.10.1590 4 65 2.4E-20 T 23-10-2018 A3L08_05180 bec090e2f7f01cfc18c55ead0dab34ce 464 Gene3D G3DSA:3.90.550.10 1 345 1.9E-112 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L08_05180 bec090e2f7f01cfc18c55ead0dab34ce 464 Gene3D G3DSA:2.60.120.10 347 451 8.6E-19 T 23-10-2018 IPR014710 RmlC-like jelly roll fold A3L08_05180 bec090e2f7f01cfc18c55ead0dab34ce 464 TIGRFAM TIGR01479 GMP_PMI: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase 3 462 2.5E-156 T 23-10-2018 IPR006375 Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase GO:0000271|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882 A3L08_05180 bec090e2f7f01cfc18c55ead0dab34ce 464 SUPERFAMILY SSF51182 191 463 1.11E-69 T 23-10-2018 IPR011051 RmlC-like cupin domain superfamily A3L08_05180 bec090e2f7f01cfc18c55ead0dab34ce 464 Pfam PF01050 Mannose-6-phosphate isomerase 309 459 2.7E-68 T 23-10-2018 IPR001538 Mannose-6-phosphate isomerase, type II, C-terminal GO:0005976|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882 A3L08_05180 bec090e2f7f01cfc18c55ead0dab34ce 464 Pfam PF00483 Nucleotidyl transferase 2 277 6.8E-59 T 23-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 A3L08_05180 bec090e2f7f01cfc18c55ead0dab34ce 464 SUPERFAMILY SSF53448 1 270 1.34E-66 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L08_02960 1016d14622dd5851938496107294e42b 331 Gene3D G3DSA:2.160.10.10 239 330 3.5E-7 T 23-10-2018 A3L08_02960 1016d14622dd5851938496107294e42b 331 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 253 281 8.9E-4 T 23-10-2018 IPR001451 Hexapeptide repeat A3L08_02960 1016d14622dd5851938496107294e42b 331 Pfam PF00483 Nucleotidyl transferase 3 234 2.5E-38 T 23-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 A3L08_02960 1016d14622dd5851938496107294e42b 331 Gene3D G3DSA:3.90.550.10 1 238 4.3E-54 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L08_02960 1016d14622dd5851938496107294e42b 331 SUPERFAMILY SSF53448 1 286 7.43E-54 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L08_08200 e3b42a02f2f0a56f40a995d806077b8b 278 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 94 269 1.9E-20 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A3L08_08200 e3b42a02f2f0a56f40a995d806077b8b 278 Gene3D G3DSA:1.10.3720.10 4 269 9.7E-63 T 23-10-2018 IPR035906 MetI-like superfamily A3L08_08200 e3b42a02f2f0a56f40a995d806077b8b 278 SUPERFAMILY SSF161098 13 278 8.13E-68 T 23-10-2018 IPR035906 MetI-like superfamily A3L08_03090 cb610e03056a549d957f593a2ea610d8 234 SUPERFAMILY SSF51161 31 197 6.86E-45 T 23-10-2018 IPR011004 Trimeric LpxA-like superfamily A3L08_03090 cb610e03056a549d957f593a2ea610d8 234 Gene3D G3DSA:2.160.10.10 18 223 1.6E-43 T 23-10-2018 A3L08_03090 cb610e03056a549d957f593a2ea610d8 234 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 33 64 9.0E-5 T 23-10-2018 IPR001451 Hexapeptide repeat A3L08_03090 cb610e03056a549d957f593a2ea610d8 234 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 122 155 1.7E-11 T 23-10-2018 IPR001451 Hexapeptide repeat A3L08_03090 cb610e03056a549d957f593a2ea610d8 234 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 129 157 - T 23-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 A3L08_05420 215aeef467d97c2b14b333b920b72444 469 PIRSF PIRSF006603 2 469 8.7E-141 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A3L08_05420 215aeef467d97c2b14b333b920b72444 469 Pfam PF01554 MatE 290 426 1.6E-26 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A3L08_05420 215aeef467d97c2b14b333b920b72444 469 Pfam PF01554 MatE 28 188 7.5E-34 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A3L08_05420 215aeef467d97c2b14b333b920b72444 469 TIGRFAM TIGR00797 matE: MATE efflux family protein 28 439 1.0E-71 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A3L08_01055 3afd316630892e365f1a6302ca5e5f79 89 Pfam PF13396 Phospholipase_D-nuclease N-terminal 23 65 7.5E-8 T 23-10-2018 IPR027379 Cardiolipin synthase N-terminal A3L08_09195 747d2b0dc444e8857e7f71f71655b770 147 Pfam PF01986 Domain of unknown function DUF123 25 110 7.0E-21 T 23-10-2018 IPR002837 Protein of unknown function DUF123 A3L08_09195 747d2b0dc444e8857e7f71f71655b770 147 SMART SM00465 18 113 1.5E-5 T 23-10-2018 IPR000305 GIY-YIG endonuclease A3L08_00535 7ae9c9cd668f4beffa7c9bb95dd6a6c0 222 Pfam PF01987 Mitochondrial biogenesis AIM24 3 205 6.8E-65 T 23-10-2018 IPR002838 Mitochondrial biogenesis protein AIM24 A3L08_00535 7ae9c9cd668f4beffa7c9bb95dd6a6c0 222 SUPERFAMILY SSF51219 1 220 6.28E-75 T 23-10-2018 IPR016031 Tryptophan RNA-binding attenuator protein-like domain superfamily A3L08_00535 7ae9c9cd668f4beffa7c9bb95dd6a6c0 222 Gene3D G3DSA:3.60.160.10 1 222 3.5E-86 T 23-10-2018 IPR036983 Mitochondrial biogenesis AIM24 superfamily A3L08_00535 7ae9c9cd668f4beffa7c9bb95dd6a6c0 222 TIGRFAM TIGR00266 TIGR00266: TIGR00266 family protein 1 220 1.1E-86 T 23-10-2018 IPR002838 Mitochondrial biogenesis protein AIM24 A3L08_00440 931a460ebd6776cecc0ed4f3cd2c9909 47 SMART SM00355 18 41 0.0078 T 23-10-2018 IPR013087 Zinc finger C2H2-type GO:0003676 A3L08_00440 931a460ebd6776cecc0ed4f3cd2c9909 47 ProSitePatterns PS00028 Zinc finger C2H2 type domain signature. 20 41 - T 23-10-2018 IPR013087 Zinc finger C2H2-type GO:0003676 A3L08_00440 931a460ebd6776cecc0ed4f3cd2c9909 47 SUPERFAMILY SSF57667 10 38 4.52E-5 T 23-10-2018 IPR036236 Zinc finger C2H2 superfamily A3L08_05315 a88dbc69a626dd746a3c59de24ebb0d3 121 SMART SM00748 7 113 2.9E-19 T 23-10-2018 IPR007842 HEPN domain A3L08_05315 a88dbc69a626dd746a3c59de24ebb0d3 121 Gene3D G3DSA:1.20.120.330 1 121 1.4E-34 T 23-10-2018 A3L08_05315 a88dbc69a626dd746a3c59de24ebb0d3 121 SUPERFAMILY SSF81593 5 118 3.49E-29 T 23-10-2018 A3L08_05315 a88dbc69a626dd746a3c59de24ebb0d3 121 Pfam PF05168 HEPN domain 3 118 4.1E-33 T 23-10-2018 IPR007842 HEPN domain A3L08_00595 953e5abe237a8ab9e11ecaf9b8628dfc 144 Pfam PF04024 PspC domain 3 61 1.4E-18 T 23-10-2018 IPR007168 Phage shock protein, PspC, N-terminal A3L08_09480 6a95666f9acb94a0c20ac983fbb545e2 138 Gene3D G3DSA:3.30.110.60 4 108 2.3E-19 T 23-10-2018 IPR035920 YhbY-like superfamily A3L08_09480 6a95666f9acb94a0c20ac983fbb545e2 138 ProDom PD010559 RNA-BINDING YHBY UPF0044 PREDICTED RNA RIBOSOMAL CONTAINING KH BINDING DOMAIN 11 95 1.0E-36 T 23-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 A3L08_09480 6a95666f9acb94a0c20ac983fbb545e2 138 SUPERFAMILY SSF75471 5 101 9.42E-17 T 23-10-2018 IPR035920 YhbY-like superfamily A3L08_09480 6a95666f9acb94a0c20ac983fbb545e2 138 Pfam PF01985 CRS1 / YhbY (CRM) domain 5 92 1.8E-10 T 23-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 A3L08_09480 6a95666f9acb94a0c20ac983fbb545e2 138 SMART SM01103 5 92 4.8E-24 T 23-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 A3L08_05840 6a5e25d20ccede5c029932da3de60811 192 SUPERFAMILY SSF56300 22 156 8.79E-21 T 23-10-2018 A3L08_05840 6a5e25d20ccede5c029932da3de60811 192 Gene3D G3DSA:3.60.21.10 15 138 1.6E-10 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like A3L08_05840 6a5e25d20ccede5c029932da3de60811 192 Pfam PF00149 Calcineurin-like phosphoesterase 23 136 4.7E-8 T 23-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 A3L08_01390 e8168cdd402e8dc1bc89e25a0934fdb4 91 SUPERFAMILY SSF54975 2 89 4.14E-32 T 23-10-2018 IPR036046 Acylphosphatase-like domain superfamily KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 A3L08_01390 e8168cdd402e8dc1bc89e25a0934fdb4 91 ProSitePatterns PS00150 Acylphosphatase signature 1. 10 20 - T 23-10-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 A3L08_01390 e8168cdd402e8dc1bc89e25a0934fdb4 91 ProSitePatterns PS00151 Acylphosphatase signature 2. 34 50 - T 23-10-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 A3L08_01390 e8168cdd402e8dc1bc89e25a0934fdb4 91 PRINTS PR00112 Acylphosphatase signature 5 20 1.5E-9 T 23-10-2018 IPR020456 Acylphosphatase GO:0003998 KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 A3L08_01390 e8168cdd402e8dc1bc89e25a0934fdb4 91 PRINTS PR00112 Acylphosphatase signature 26 51 1.5E-9 T 23-10-2018 IPR020456 Acylphosphatase GO:0003998 KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 A3L08_01390 e8168cdd402e8dc1bc89e25a0934fdb4 91 Pfam PF00708 Acylphosphatase 7 88 4.1E-29 T 23-10-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 A3L08_01390 e8168cdd402e8dc1bc89e25a0934fdb4 91 Gene3D G3DSA:3.30.70.100 1 91 4.7E-39 T 23-10-2018 A3L08_03290 a47bc1e0c60fa04dd3eaa96a2da2139b 189 PRINTS PR00096 Glutamine amidotransferase superfamily signature 46 55 1.4E-9 T 23-10-2018 A3L08_03290 a47bc1e0c60fa04dd3eaa96a2da2139b 189 PRINTS PR00096 Glutamine amidotransferase superfamily signature 161 174 1.4E-9 T 23-10-2018 A3L08_03290 a47bc1e0c60fa04dd3eaa96a2da2139b 189 PRINTS PR00096 Glutamine amidotransferase superfamily signature 73 84 1.4E-9 T 23-10-2018 A3L08_03290 a47bc1e0c60fa04dd3eaa96a2da2139b 189 SUPERFAMILY SSF52317 1 186 3.52E-55 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A3L08_03290 a47bc1e0c60fa04dd3eaa96a2da2139b 189 Hamap MF_01510 GMP synthase [glutamine-hydrolyzing] subunit A [guaAA]. 1 187 44.859 T 23-10-2018 IPR023686 GMP synthase (glutamine-hydrolyzing) subunit A GO:0003922 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 A3L08_03290 a47bc1e0c60fa04dd3eaa96a2da2139b 189 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 43 57 1.3E-5 T 23-10-2018 A3L08_03290 a47bc1e0c60fa04dd3eaa96a2da2139b 189 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 73 89 1.3E-5 T 23-10-2018 A3L08_03290 a47bc1e0c60fa04dd3eaa96a2da2139b 189 Gene3D G3DSA:3.40.50.880 1 187 6.1E-60 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A3L08_03290 a47bc1e0c60fa04dd3eaa96a2da2139b 189 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 2 186 7.1E-81 T 23-10-2018 IPR004739 GMP synthase, glutamine amidotransferase GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 A3L08_03290 a47bc1e0c60fa04dd3eaa96a2da2139b 189 Pfam PF00117 Glutamine amidotransferase class-I 4 181 1.4E-44 T 23-10-2018 IPR017926 Glutamine amidotransferase A3L08_03290 a47bc1e0c60fa04dd3eaa96a2da2139b 189 PRINTS PR00097 Anthranilate synthase component II signature 46 55 2.4E-11 T 23-10-2018 A3L08_03290 a47bc1e0c60fa04dd3eaa96a2da2139b 189 PRINTS PR00097 Anthranilate synthase component II signature 2 16 2.4E-11 T 23-10-2018 A3L08_03290 a47bc1e0c60fa04dd3eaa96a2da2139b 189 PRINTS PR00097 Anthranilate synthase component II signature 73 84 2.4E-11 T 23-10-2018 A3L08_03290 a47bc1e0c60fa04dd3eaa96a2da2139b 189 PRINTS PR00097 Anthranilate synthase component II signature 161 174 2.4E-11 T 23-10-2018 A3L08_07855 8680020283bbcf207a97158a96409b0d 97 SUPERFAMILY SSF101386 1 79 3.27E-21 T 23-10-2018 A3L08_07855 8680020283bbcf207a97158a96409b0d 97 Gene3D G3DSA:1.10.287.1080 1 79 1.8E-28 T 23-10-2018 A3L08_07855 8680020283bbcf207a97158a96409b0d 97 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 25 77 9.6E-15 T 23-10-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core A3L08_09050 ebf956a6b6c02a924f52619c1f10d93a 133 Pfam PF05763 Protein of unknown function (DUF835) 23 131 4.2E-18 T 23-10-2018 IPR008553 Domain of unknown function DUF835 A3L08_04370 cbf51a4b85dc57acd1a06b73036f1cb2 277 ProSitePatterns PS01232 Purine and other phosphorylases family 1 signature. 76 91 - T 23-10-2018 IPR018016 Nucleoside phosphorylase, conserved site GO:0016763 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-73614|Reactome: R-HSA-73621 A3L08_04370 cbf51a4b85dc57acd1a06b73036f1cb2 277 Gene3D G3DSA:3.40.50.1580 7 261 1.6E-86 T 23-10-2018 A3L08_04370 cbf51a4b85dc57acd1a06b73036f1cb2 277 SUPERFAMILY SSF53167 18 247 7.46E-76 T 23-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 A3L08_04370 cbf51a4b85dc57acd1a06b73036f1cb2 277 TIGRFAM TIGR01718 Uridine-psphlse: uridine phosphorylase 18 257 1.7E-97 T 23-10-2018 IPR010058 Uridine phosphorylase GO:0004850|GO:0005737|GO:0009166 KEGG: 00240+2.4.2.3|KEGG: 00983+2.4.2.3|MetaCyc: PWY-5532 A3L08_04370 cbf51a4b85dc57acd1a06b73036f1cb2 277 Pfam PF01048 Phosphorylase superfamily 31 256 1.6E-45 T 23-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 A3L08_08920 7920a3796593ec40ff17e6d9a06e2293 173 Pfam PF02632 BioY family 26 168 7.8E-40 T 23-10-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 A3L08_08920 7920a3796593ec40ff17e6d9a06e2293 173 PIRSF PIRSF016661 1 173 9.0E-46 T 23-10-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 A3L08_08920 7920a3796593ec40ff17e6d9a06e2293 173 Gene3D G3DSA:1.10.1760.20 1 172 6.6E-55 T 23-10-2018 A3L08_07070 cd8836a35ebab778b3c9563bb409d403 242 SUPERFAMILY SSF110849 12 241 6.54E-61 T 23-10-2018 IPR036086 ParB/Sulfiredoxin superfamily A3L08_07070 cd8836a35ebab778b3c9563bb409d403 242 Gene3D G3DSA:3.90.1530.10 17 238 2.0E-83 T 23-10-2018 A3L08_07070 cd8836a35ebab778b3c9563bb409d403 242 Gene3D G3DSA:3.30.1760.10 98 227 2.0E-83 T 23-10-2018 IPR023098 ParB-like nuclease, C-terminal A3L08_07070 cd8836a35ebab778b3c9563bb409d403 242 SMART SM00470 19 114 4.5E-11 T 23-10-2018 IPR003115 ParB/Sulfiredoxin A3L08_07070 cd8836a35ebab778b3c9563bb409d403 242 Pfam PF02195 ParB-like nuclease domain 22 92 2.0E-9 T 23-10-2018 IPR003115 ParB/Sulfiredoxin A3L08_05215 998b6ec72f6ac5e9a27609e2f3009805 319 SMART SM00028 81 114 21.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A3L08_05215 998b6ec72f6ac5e9a27609e2f3009805 319 SMART SM00028 121 154 0.041 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A3L08_05215 998b6ec72f6ac5e9a27609e2f3009805 319 Gene3D G3DSA:1.25.40.10 29 232 9.3E-15 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A3L08_05215 998b6ec72f6ac5e9a27609e2f3009805 319 Pfam PF13424 Tetratricopeptide repeat 85 152 4.3E-8 T 23-10-2018 A3L08_05215 998b6ec72f6ac5e9a27609e2f3009805 319 SUPERFAMILY SSF48452 76 190 1.99E-13 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A3L08_08075 69a02d19ff41ff56b323974339e2f3f3 196 Gene3D G3DSA:3.40.109.10 1 195 1.4E-76 T 23-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A3L08_08075 69a02d19ff41ff56b323974339e2f3f3 196 Pfam PF00881 Nitroreductase family 20 193 2.7E-33 T 23-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 A3L08_08075 69a02d19ff41ff56b323974339e2f3f3 196 SUPERFAMILY SSF55469 14 195 2.55E-41 T 23-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A3L08_08075 69a02d19ff41ff56b323974339e2f3f3 196 TIGRFAM TIGR03605 antibiot_sagB: SagB-type dehydrogenase domain 35 193 2.3E-46 T 23-10-2018 IPR020051 SagB-type dehydrogenase domain A3L08_05740 c441cfa914391da654ce8b966e17d250 175 SUPERFAMILY SSF47240 18 172 1.1E-18 T 23-10-2018 IPR009078 Ferritin-like superfamily A3L08_05740 c441cfa914391da654ce8b966e17d250 175 Pfam PF02915 Rubrerythrin 27 166 2.6E-13 T 23-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 A3L08_05740 c441cfa914391da654ce8b966e17d250 175 Gene3D G3DSA:1.20.1260.10 17 170 1.4E-26 T 23-10-2018 IPR012347 Ferritin-like A3L08_00810 12898d56ba5a757957771bf295dfaf70 178 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 21 132 2.4E-28 T 23-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain A3L08_00810 12898d56ba5a757957771bf295dfaf70 178 SUPERFAMILY SSF53927 22 143 1.47E-39 T 23-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 A3L08_00810 12898d56ba5a757957771bf295dfaf70 178 PIRSF PIRSF006019 12 168 2.8E-56 T 23-10-2018 IPR016473 Deoxycytidylate deaminase GO:0004132|GO:0006220|GO:0008270 KEGG: 00240+3.5.4.12|MetaCyc: PWY-7210|Reactome: R-HSA-499943 A3L08_00810 12898d56ba5a757957771bf295dfaf70 178 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 86 121 - T 23-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 A3L08_00810 12898d56ba5a757957771bf295dfaf70 178 Gene3D G3DSA:3.40.140.10 18 167 7.0E-48 T 23-10-2018 A3L08_08480 f119df9da39d4820e2fb807411d11fd2 290 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 3 264 6.1E-20 T 23-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain A3L08_08480 f119df9da39d4820e2fb807411d11fd2 290 Gene3D G3DSA:3.30.70.20 62 116 1.0E-9 T 23-10-2018 A3L08_08480 f119df9da39d4820e2fb807411d11fd2 290 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 100 111 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L08_08480 f119df9da39d4820e2fb807411d11fd2 290 Pfam PF12837 4Fe-4S binding domain 63 85 3.0E-6 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L08_08480 f119df9da39d4820e2fb807411d11fd2 290 SUPERFAMILY SSF52540 3 286 1.26E-31 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_08480 f119df9da39d4820e2fb807411d11fd2 290 SUPERFAMILY SSF54862 48 113 2.41E-13 T 23-10-2018 A3L08_07690 f020f555ab81003390da4620b4599be9 193 SUPERFAMILY SSF55729 13 146 1.14E-7 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase A3L08_07690 f020f555ab81003390da4620b4599be9 193 Gene3D G3DSA:3.40.630.30 1 166 1.2E-20 T 23-10-2018 A3L08_08115 1b10b0fcdf25b4c03bb7458baa37f80f 235 Gene3D G3DSA:3.20.20.70 2 232 5.4E-70 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L08_08115 1b10b0fcdf25b4c03bb7458baa37f80f 235 ProSitePatterns PS00614 Indole-3-glycerol phosphate synthase signature. 18 33 - T 23-10-2018 IPR001468 Indole-3-glycerol phosphate synthase, conserved site GO:0004425|GO:0006568 KEGG: 00400+4.1.1.48 A3L08_08115 1b10b0fcdf25b4c03bb7458baa37f80f 235 SUPERFAMILY SSF51366 4 225 4.08E-60 T 23-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 A3L08_08115 1b10b0fcdf25b4c03bb7458baa37f80f 235 Pfam PF00218 Indole-3-glycerol phosphate synthase 7 223 1.7E-55 T 23-10-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 A3L08_08115 1b10b0fcdf25b4c03bb7458baa37f80f 235 Hamap MF_00134_A Indole-3-glycerol phosphate synthase [trpC]. 1 221 30.647 T 23-10-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 A3L08_09405 98d103b02f082cffadfc3f9cce842887 232 PIRSF PIRSF005928 10 232 2.9E-102 T 23-10-2018 IPR009185 Predicted nucleotidyltransferase A3L08_09405 98d103b02f082cffadfc3f9cce842887 232 SUPERFAMILY SSF81301 20 74 3.16E-8 T 23-10-2018 A3L08_09405 98d103b02f082cffadfc3f9cce842887 232 Pfam PF01909 Nucleotidyltransferase domain 35 106 4.2E-7 T 23-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 A3L08_09405 98d103b02f082cffadfc3f9cce842887 232 Gene3D G3DSA:3.30.460.10 20 97 9.8E-7 T 23-10-2018 A3L08_00345 5caf350f73ed80f1d474e02c3e4320b8 268 Gene3D G3DSA:1.10.357.140 17 163 3.4E-11 T 23-10-2018 A3L08_00345 5caf350f73ed80f1d474e02c3e4320b8 268 Pfam PF01040 UbiA prenyltransferase family 21 237 4.7E-36 T 23-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 A3L08_09190 5c3d456441d3bbf04ebdff02e514e884 131 Pfam PF09868 Uncharacterized protein conserved in archaea (DUF2095) 4 129 6.4E-65 T 23-10-2018 IPR018662 Protein of unknown function DUF2095 A3L08_04220 0b72d7128698849cdf07a20dcc87aea3 180 ProSitePatterns PS00632 Ribosomal protein S4 signature. 101 125 - T 23-10-2018 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_04220 0b72d7128698849cdf07a20dcc87aea3 180 Hamap MF_01306_A 30S ribosomal protein S4 [rpsD]. 1 156 33.902 T 23-10-2018 IPR022802 Ribosomal protein S4, archaeal GO:0006412|GO:0019843 A3L08_04220 0b72d7128698849cdf07a20dcc87aea3 180 SMART SM00363 103 165 2.7E-15 T 23-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_04220 0b72d7128698849cdf07a20dcc87aea3 180 Gene3D G3DSA:3.10.290.10 104 176 7.8E-17 T 23-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 A3L08_04220 0b72d7128698849cdf07a20dcc87aea3 180 SMART SM01390 5 102 1.0E-6 T 23-10-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 A3L08_04220 0b72d7128698849cdf07a20dcc87aea3 180 SUPERFAMILY SSF55174 9 160 5.5E-34 T 23-10-2018 A3L08_04220 0b72d7128698849cdf07a20dcc87aea3 180 TIGRFAM TIGR01018 uS4_arch: ribosomal protein uS4 1 161 4.3E-75 T 23-10-2018 IPR005710 Ribosomal protein S4/S9, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_04220 0b72d7128698849cdf07a20dcc87aea3 180 Pfam PF01479 S4 domain 103 148 1.9E-16 T 23-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_00220 a250bffe7d9970ca3da9e28ca6bafdcf 127 Pfam PF09946 Predicted membrane protein (DUF2178) 11 111 4.3E-13 T 23-10-2018 IPR019235 Protein of unknown function DUF2178, transmembrane A3L08_08505 cf9ba34f3bba399fb5dc778b82c5e01c 315 SUPERFAMILY SSF102114 25 217 3.79E-23 T 23-10-2018 A3L08_08505 cf9ba34f3bba399fb5dc778b82c5e01c 315 Pfam PF04055 Radical SAM superfamily 25 192 7.5E-15 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L08_08505 cf9ba34f3bba399fb5dc778b82c5e01c 315 Gene3D G3DSA:3.20.20.70 19 258 4.1E-22 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L08_08505 cf9ba34f3bba399fb5dc778b82c5e01c 315 SMART SM00729 15 228 0.0017 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A3L08_03470 513d3a76ef818c45b490617ab3fcaf3e 266 Gene3D G3DSA:3.40.50.150 7 197 9.8E-19 T 23-10-2018 A3L08_03470 513d3a76ef818c45b490617ab3fcaf3e 266 SUPERFAMILY SSF53335 30 211 7.0E-24 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L08_03470 513d3a76ef818c45b490617ab3fcaf3e 266 Pfam PF13649 Methyltransferase domain 44 143 8.7E-12 T 23-10-2018 A3L08_00935 94c12dc908a882e8532ae11c06d6d360 234 Pfam PF07758 Protein of unknown function (DUF1614) 56 233 1.4E-56 T 23-10-2018 IPR011672 Protein of unknown function DUF1614 A3L08_06035 126b840c75f9e95eb3f3914c5dc0d599 94 Gene3D G3DSA:3.30.310.50 9 94 9.3E-25 T 23-10-2018 A3L08_06035 126b840c75f9e95eb3f3914c5dc0d599 94 Pfam PF09341 Transcription factor Pcc1 22 92 2.8E-12 T 23-10-2018 IPR015419 CTAG/Pcc1 family A3L08_02940 71db8f771957ca24737e9eb2ce72ac44 154 SUPERFAMILY SSF53271 2 146 7.34E-34 T 23-10-2018 IPR029057 Phosphoribosyltransferase-like A3L08_02940 71db8f771957ca24737e9eb2ce72ac44 154 Gene3D G3DSA:3.40.50.2020 1 154 5.1E-52 T 23-10-2018 A3L08_02940 71db8f771957ca24737e9eb2ce72ac44 154 Pfam PF00156 Phosphoribosyl transferase domain 14 151 1.5E-27 T 23-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 A3L08_06345 693a1ab9203d76856dabb7e89bdc1ee5 188 Gene3D G3DSA:1.10.10.10 124 186 4.1E-6 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L08_06345 693a1ab9203d76856dabb7e89bdc1ee5 188 Pfam PF08279 HTH domain 145 177 1.9E-4 T 23-10-2018 IPR013196 Helix-turn-helix, type 11 A3L08_03495 3db983bd0e70ac3136519acef84ade1f 243 Pfam PF10086 Putative membrane peptidase family (DUF2324) 21 127 3.5E-6 T 23-10-2018 IPR011397 Uncharacterised conserved protein UCP033101 A3L08_03495 3db983bd0e70ac3136519acef84ade1f 243 Pfam PF10086 Putative membrane peptidase family (DUF2324) 135 194 1.4E-5 T 23-10-2018 IPR011397 Uncharacterised conserved protein UCP033101 A3L08_01940 8788df92700fb20be1164264c52006a8 171 Pfam PF01864 CDP-archaeol synthase 6 171 1.3E-58 T 23-10-2018 IPR032690 CDP-archaeol synthase KEGG: 00564+2.7.7.67|MetaCyc: PWY-6349 A3L08_01940 8788df92700fb20be1164264c52006a8 171 Hamap MF_01117 CDP-archaeol synthase [carS]. 14 171 28.057 T 23-10-2018 IPR002726 CDP-archaeol synthase, archaea KEGG: 00564+2.7.7.67|MetaCyc: PWY-6349 A3L08_09775 e956851d5fd0794e365ec69e80344c0d 221 SUPERFAMILY SSF118196 4 139 3.27E-39 T 23-10-2018 IPR036413 YaeB-like superfamily A3L08_09775 e956851d5fd0794e365ec69e80344c0d 221 Gene3D G3DSA:2.40.30.70 8 145 3.7E-33 T 23-10-2018 IPR036414 YaeB, N-terminal domain superfamily A3L08_09775 e956851d5fd0794e365ec69e80344c0d 221 ProSitePatterns PS01318 TsaA-like domain signature. 76 87 - T 23-10-2018 IPR023368 Uncharacterised protein family UPF0066, conserved site A3L08_09775 e956851d5fd0794e365ec69e80344c0d 221 TIGRFAM TIGR00104 tRNA_TsaA: tRNA-Thr(GGU) m(6)t(6)A37 methyltransferase TsaA 21 133 3.4E-36 T 23-10-2018 IPR023370 YaeB-like, N-terminal domain A3L08_09775 e956851d5fd0794e365ec69e80344c0d 221 Pfam PF01980 Uncharacterised protein family UPF0066 19 128 1.6E-30 T 23-10-2018 IPR023370 YaeB-like, N-terminal domain A3L08_08660 23ca74a6ff81c058a8d3de68423ec82a 1120 SUPERFAMILY SSF88697 667 788 6.46E-5 T 23-10-2018 IPR015947 PUA-like superfamily A3L08_08660 23ca74a6ff81c058a8d3de68423ec82a 1120 SMART SM00382 623 986 1.1E-7 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L08_08660 23ca74a6ff81c058a8d3de68423ec82a 1120 Pfam PF07728 AAA domain (dynein-related subfamily) 883 976 2.1E-9 T 23-10-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 A3L08_08660 23ca74a6ff81c058a8d3de68423ec82a 1120 SUPERFAMILY SSF52540 607 986 2.77E-13 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_06405 827f7bfb8a56da2691f5ef9d87b7003d 237 Pfam PF01940 Integral membrane protein DUF92 11 215 6.8E-53 T 23-10-2018 IPR002794 Protein of unknown function DUF92, TMEM19 GO:0016021 A3L08_00255 6b127eead283bde41a7363e828282811 137 Hamap MF_01112 UPF0201 protein . 5 134 25.056 T 23-10-2018 IPR002739 Uncharacterised protein family UPF0201 A3L08_00255 6b127eead283bde41a7363e828282811 137 Pfam PF01877 RNA binding 6 115 4.9E-18 T 23-10-2018 IPR002739 Uncharacterised protein family UPF0201 A3L08_00255 6b127eead283bde41a7363e828282811 137 Gene3D G3DSA:3.30.1440.10 1 136 2.0E-45 T 23-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_00255 6b127eead283bde41a7363e828282811 137 SUPERFAMILY SSF55282 6 136 1.03E-40 T 23-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_01765 6c07dfc4cff7fef9ce06644d921efbaf 119 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 6 115 2.9E-27 T 23-10-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like A3L08_00450 eee1bea7fa955da19410f20a4df77deb 224 SUPERFAMILY SSF56281 1 223 1.44E-39 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L08_00450 eee1bea7fa955da19410f20a4df77deb 224 SMART SM00849 8 189 1.1E-19 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L08_00450 eee1bea7fa955da19410f20a4df77deb 224 Pfam PF13483 Beta-lactamase superfamily domain 3 189 1.1E-33 T 23-10-2018 A3L08_00450 eee1bea7fa955da19410f20a4df77deb 224 Hamap MF_00457 UPF0173 metal-dependent hydrolase . 2 224 38.954 T 23-10-2018 IPR022877 Protein of unknown funcion UPF0173 A3L08_00450 eee1bea7fa955da19410f20a4df77deb 224 Gene3D G3DSA:3.60.15.10 2 224 6.2E-74 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L08_04985 1fad4cb356a5ceb0aa8c2424f0f5b122 228 PIRSF PIRSF000887 4 224 2.3E-61 T 23-10-2018 IPR024173 Phosphoesterase, MJ0037 A3L08_04985 1fad4cb356a5ceb0aa8c2424f0f5b122 228 TIGRFAM TIGR00024 SbcD_rel_arch: putative phosphoesterase 9 220 1.7E-48 T 23-10-2018 IPR004376 Conserved hypothetical protein CHP00024, phosphoesterase-like A3L08_04985 1fad4cb356a5ceb0aa8c2424f0f5b122 228 Pfam PF00149 Calcineurin-like phosphoesterase 15 112 7.3E-7 T 23-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 A3L08_04985 1fad4cb356a5ceb0aa8c2424f0f5b122 228 Gene3D G3DSA:3.60.21.10 13 152 7.3E-11 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like A3L08_04985 1fad4cb356a5ceb0aa8c2424f0f5b122 228 SUPERFAMILY SSF56300 15 124 1.1E-15 T 23-10-2018 A3L08_08265 4a23a8a65affb9ec1033f30ae5388255 126 SUPERFAMILY SSF117916 27 90 1.93E-10 T 23-10-2018 IPR034904 Fe-S cluster assembly domain superfamily A3L08_08265 4a23a8a65affb9ec1033f30ae5388255 126 Gene3D G3DSA:3.30.300.130 25 109 3.8E-12 T 23-10-2018 IPR034904 Fe-S cluster assembly domain superfamily A3L08_08265 4a23a8a65affb9ec1033f30ae5388255 126 Pfam PF01883 Iron-sulfur cluster assembly protein 28 89 1.6E-9 T 23-10-2018 IPR002744 MIP18 family-like A3L08_08405 18e646aef75e688ed2d83b10abec674b 427 Gene3D G3DSA:1.10.3860.10 2 427 2.2E-169 T 23-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 A3L08_08405 18e646aef75e688ed2d83b10abec674b 427 Pfam PF00375 Sodium:dicarboxylate symporter family 13 415 6.5E-123 T 23-10-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A3L08_08405 18e646aef75e688ed2d83b10abec674b 427 SUPERFAMILY SSF118215 13 417 1.09E-119 T 23-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 A3L08_08405 18e646aef75e688ed2d83b10abec674b 427 PRINTS PR00173 Glutamate-aspartate symporter signature 53 73 1.4E-52 T 23-10-2018 A3L08_08405 18e646aef75e688ed2d83b10abec674b 427 PRINTS PR00173 Glutamate-aspartate symporter signature 82 107 1.4E-52 T 23-10-2018 A3L08_08405 18e646aef75e688ed2d83b10abec674b 427 PRINTS PR00173 Glutamate-aspartate symporter signature 363 383 1.4E-52 T 23-10-2018 A3L08_08405 18e646aef75e688ed2d83b10abec674b 427 PRINTS PR00173 Glutamate-aspartate symporter signature 201 220 1.4E-52 T 23-10-2018 A3L08_08405 18e646aef75e688ed2d83b10abec674b 427 PRINTS PR00173 Glutamate-aspartate symporter signature 301 327 1.4E-52 T 23-10-2018 A3L08_08405 18e646aef75e688ed2d83b10abec674b 427 PRINTS PR00173 Glutamate-aspartate symporter signature 232 251 1.4E-52 T 23-10-2018 A3L08_08405 18e646aef75e688ed2d83b10abec674b 427 PRINTS PR00173 Glutamate-aspartate symporter signature 336 355 1.4E-52 T 23-10-2018 A3L08_08405 18e646aef75e688ed2d83b10abec674b 427 PRINTS PR00173 Glutamate-aspartate symporter signature 10 30 1.4E-52 T 23-10-2018 A3L08_08405 18e646aef75e688ed2d83b10abec674b 427 ProSitePatterns PS00713 Sodium:dicarboxylate symporter family signature 1. 45 60 - T 23-10-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site A3L08_03660 d77b9cf784bc8379f201cce7d9cef23a 334 Gene3D G3DSA:3.40.50.300 3 236 4.5E-75 T 23-10-2018 A3L08_03660 d77b9cf784bc8379f201cce7d9cef23a 334 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A3L08_03660 d77b9cf784bc8379f201cce7d9cef23a 334 SUPERFAMILY SSF52540 4 241 1.69E-88 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_03660 d77b9cf784bc8379f201cce7d9cef23a 334 SMART SM00382 27 210 1.8E-16 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L08_03660 d77b9cf784bc8379f201cce7d9cef23a 334 Pfam PF00005 ABC transporter 22 160 8.1E-36 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A3L08_03675 50cc09d042565dc3d305f11210ed0b23 536 SMART SM00729 215 448 3.5E-4 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A3L08_03675 50cc09d042565dc3d305f11210ed0b23 536 SUPERFAMILY SSF102114 216 457 2.62E-13 T 23-10-2018 A3L08_03675 50cc09d042565dc3d305f11210ed0b23 536 Pfam PF04055 Radical SAM superfamily 219 403 1.5E-18 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L08_03675 50cc09d042565dc3d305f11210ed0b23 536 Gene3D G3DSA:3.80.30.20 215 410 1.1E-13 T 23-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe A3L08_01085 ffe75994a3dc219e485d877cecb9e3a1 151 SUPERFAMILY SSF54893 3 98 3.4E-33 T 23-10-2018 IPR036793 Aspartate carbamoyltransferase regulatory subunit, N-terminal domain superfamily A3L08_01085 ffe75994a3dc219e485d877cecb9e3a1 151 Pfam PF02748 Aspartate carbamoyltransferase regulatory chain, metal binding domain 100 147 3.0E-21 T 23-10-2018 IPR020542 Aspartate carbamoyltransferase regulatory subunit, C-terminal A3L08_01085 ffe75994a3dc219e485d877cecb9e3a1 151 ProDom PD006194 REGULATORY ASPARTATE CARBAMOYLTRANSFERASE CHAIN METAL-BINDING ZINC PYRIMIDINE BIOSYNTHESIS SUBUNIT TRANSFERASE 6 97 5.0E-35 T 23-10-2018 IPR020545 Aspartate carbamoyltransferase regulatory subunit, N-terminal A3L08_01085 ffe75994a3dc219e485d877cecb9e3a1 151 Gene3D G3DSA:2.30.30.20 98 148 4.1E-23 T 23-10-2018 A3L08_01085 ffe75994a3dc219e485d877cecb9e3a1 151 SUPERFAMILY SSF57825 100 148 5.36E-17 T 23-10-2018 IPR036792 Aspartate carbamoyltransferase regulatory subunit, C-terminal domain superfamily A3L08_01085 ffe75994a3dc219e485d877cecb9e3a1 151 Pfam PF01948 Aspartate carbamoyltransferase regulatory chain, allosteric domain 4 95 1.2E-33 T 23-10-2018 IPR020545 Aspartate carbamoyltransferase regulatory subunit, N-terminal A3L08_01085 ffe75994a3dc219e485d877cecb9e3a1 151 Hamap MF_00002 Aspartate carbamoyltransferase regulatory chain [pyrI]. 1 149 34.708 T 23-10-2018 IPR002801 Aspartate transcarbamylase regulatory subunit GO:0006207|GO:0009347 A3L08_01085 ffe75994a3dc219e485d877cecb9e3a1 151 TIGRFAM TIGR00240 ATCase_reg: aspartate carbamoyltransferase, regulatory subunit 2 148 6.0E-63 T 23-10-2018 IPR002801 Aspartate transcarbamylase regulatory subunit GO:0006207|GO:0009347 A3L08_01085 ffe75994a3dc219e485d877cecb9e3a1 151 Gene3D G3DSA:3.30.70.140 1 97 8.3E-37 T 23-10-2018 IPR036793 Aspartate carbamoyltransferase regulatory subunit, N-terminal domain superfamily A3L08_08105 001ea1627cd7628bfa294a5f677c1910 404 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 307 315 - T 23-10-2018 IPR018120 Glycoside hydrolase family 1, active site A3L08_08105 001ea1627cd7628bfa294a5f677c1910 404 Gene3D G3DSA:3.20.20.80 1 400 1.1E-125 T 23-10-2018 A3L08_08105 001ea1627cd7628bfa294a5f677c1910 404 PRINTS PR00131 Glycosyl hydrolase family 1 signature 340 357 2.0E-18 T 23-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A3L08_08105 001ea1627cd7628bfa294a5f677c1910 404 PRINTS PR00131 Glycosyl hydrolase family 1 signature 364 376 2.0E-18 T 23-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A3L08_08105 001ea1627cd7628bfa294a5f677c1910 404 PRINTS PR00131 Glycosyl hydrolase family 1 signature 307 315 2.0E-18 T 23-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A3L08_08105 001ea1627cd7628bfa294a5f677c1910 404 PRINTS PR00131 Glycosyl hydrolase family 1 signature 247 261 2.0E-18 T 23-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A3L08_08105 001ea1627cd7628bfa294a5f677c1910 404 PRINTS PR00131 Glycosyl hydrolase family 1 signature 319 330 2.0E-18 T 23-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A3L08_08105 001ea1627cd7628bfa294a5f677c1910 404 SUPERFAMILY SSF51445 3 392 5.06E-114 T 23-10-2018 IPR017853 Glycoside hydrolase superfamily A3L08_08105 001ea1627cd7628bfa294a5f677c1910 404 Pfam PF00232 Glycosyl hydrolase family 1 3 391 8.8E-81 T 23-10-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 A3L08_05275 592acc25a974e9dfbed0dcf0c4200a2f 244 Pfam PF01925 Sulfite exporter TauE/SafE 7 238 2.4E-41 T 23-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 A3L08_06965 4f98b7d5490a2c03af7eb206735f9079 1077 Gene3D G3DSA:2.60.120.180 329 605 8.6E-34 T 23-10-2018 IPR013319 Glycoside hydrolase family 11/12 GO:0004553 MetaCyc: PWY-6717|MetaCyc: PWY-6784 A3L08_06965 4f98b7d5490a2c03af7eb206735f9079 1077 Gene3D G3DSA:2.60.120.180 46 310 2.1E-31 T 23-10-2018 IPR013319 Glycoside hydrolase family 11/12 GO:0004553 MetaCyc: PWY-6717|MetaCyc: PWY-6784 A3L08_06965 4f98b7d5490a2c03af7eb206735f9079 1077 Gene3D G3DSA:2.60.120.180 813 1068 1.8E-26 T 23-10-2018 IPR013319 Glycoside hydrolase family 11/12 GO:0004553 MetaCyc: PWY-6717|MetaCyc: PWY-6784 A3L08_00490 baa886b8853d2d6737bddc010d55fe08 280 SUPERFAMILY SSF52096 65 240 1.36E-28 T 23-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A3L08_00490 baa886b8853d2d6737bddc010d55fe08 280 Pfam PF01972 Serine dehydrogenase proteinase 1 277 5.7E-155 T 23-10-2018 IPR002825 Peptidase S49, serine-peptidase prokaryotes GO:0016021 A3L08_00490 baa886b8853d2d6737bddc010d55fe08 280 Gene3D G3DSA:3.90.226.10 57 268 3.2E-24 T 23-10-2018 A3L08_01240 9cac911aac0b69f5fd86b65f9935a3a0 286 Pfam PF05681 Fumarate hydratase (Fumerase) 6 272 1.2E-95 T 23-10-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 A3L08_01240 9cac911aac0b69f5fd86b65f9935a3a0 286 TIGRFAM TIGR00722 ttdA_fumA_fumB: hydrolyase, tartrate alpha subunit/fumarate domain protein, Fe-S type 5 275 1.3E-121 T 23-10-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 A3L08_03690 e28880dd28e72eaae4d0e08a85b9b3be 374 Pfam PF04123 Domain of unknown function (DUF373) 3 349 9.6E-96 T 23-10-2018 IPR007254 Protein of unknown function DUF373 A3L08_00500 d190443814ddc669f9a8199701570aae 141 Pfam PF04009 Protein of unknown function (DUF356) 5 110 9.7E-35 T 23-10-2018 IPR007154 Protein of unknown function DUF356 A3L08_00500 d190443814ddc669f9a8199701570aae 141 PIRSF PIRSF006606 3 133 1.3E-45 T 23-10-2018 IPR007154 Protein of unknown function DUF356 A3L08_01545 21de228816781b16fc69fda602355d67 487 Gene3D G3DSA:2.130.10.10 16 385 4.3E-6 T 23-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 A3L08_01545 21de228816781b16fc69fda602355d67 487 Pfam PF09910 Uncharacterized protein conserved in archaea (DUF2139) 31 361 1.7E-150 T 23-10-2018 IPR016675 Uncharacterised conserved protein UCP016666 A3L08_01545 21de228816781b16fc69fda602355d67 487 PIRSF PIRSF016666 1 487 9.2E-246 T 23-10-2018 IPR016675 Uncharacterised conserved protein UCP016666 A3L08_01545 21de228816781b16fc69fda602355d67 487 SUPERFAMILY SSF50998 15 212 1.1E-9 T 23-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily A3L08_02245 808fc47e83cce2facdb451a4643e95ce 370 Pfam PF01494 FAD binding domain 3 269 6.5E-15 T 23-10-2018 IPR002938 FAD-binding domain GO:0071949 A3L08_02245 808fc47e83cce2facdb451a4643e95ce 370 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 134 149 1.7E-11 T 23-10-2018 A3L08_02245 808fc47e83cce2facdb451a4643e95ce 370 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 244 259 1.7E-11 T 23-10-2018 A3L08_02245 808fc47e83cce2facdb451a4643e95ce 370 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 1.7E-11 T 23-10-2018 A3L08_02245 808fc47e83cce2facdb451a4643e95ce 370 Gene3D G3DSA:3.50.50.60 1 367 8.4E-57 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L08_02245 808fc47e83cce2facdb451a4643e95ce 370 TIGRFAM TIGR02032 GG-red-SF: geranylgeranyl reductase family 3 272 1.2E-52 T 23-10-2018 IPR011777 Geranylgeranyl reductase family GO:0016628|GO:0055114 A3L08_02245 808fc47e83cce2facdb451a4643e95ce 370 SUPERFAMILY SSF51905 2 285 6.68E-34 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L08_04290 03a1a03de21d6853b43d998b1325f995 109 Gene3D G3DSA:1.10.10.10 2 107 3.7E-26 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L08_04290 03a1a03de21d6853b43d998b1325f995 109 SUPERFAMILY SSF46785 3 107 1.82E-23 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L08_04290 03a1a03de21d6853b43d998b1325f995 109 Pfam PF03551 Transcriptional regulator PadR-like family 21 93 8.0E-19 T 23-10-2018 IPR005149 Transcription regulator PadR, N-terminal A3L08_03450 abc9ee0954feaecb702dd54769cc4d11 113 SUPERFAMILY SSF46785 3 105 1.86E-16 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L08_03450 abc9ee0954feaecb702dd54769cc4d11 113 Gene3D G3DSA:1.10.10.10 1 109 7.7E-35 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L08_03450 abc9ee0954feaecb702dd54769cc4d11 113 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 12 83 5.6E-9 T 23-10-2018 IPR002831 Transcription regulator TrmB, N-terminal A3L08_08705 ffa4241a0380a548f769f8c162423a73 163 Pfam PF00589 Phage integrase family 58 152 4.0E-10 T 23-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 A3L08_08705 ffa4241a0380a548f769f8c162423a73 163 SUPERFAMILY SSF56349 62 154 3.24E-13 T 23-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A3L08_08705 ffa4241a0380a548f769f8c162423a73 163 Gene3D G3DSA:1.10.443.10 37 162 2.9E-13 T 23-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 A3L08_06305 b95ed9d7336e0d5e76ffae7d66ffcbd8 189 Gene3D G3DSA:1.25.10.10 18 157 2.1E-10 T 23-10-2018 IPR011989 Armadillo-like helical A3L08_06305 b95ed9d7336e0d5e76ffae7d66ffcbd8 189 SUPERFAMILY SSF48371 34 147 1.73E-14 T 23-10-2018 IPR016024 Armadillo-type fold A3L08_04955 071b7eb5f4026f3cdf88494cf29f3ff8 413 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 6.9E-24 T 23-10-2018 A3L08_04955 071b7eb5f4026f3cdf88494cf29f3ff8 413 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 276 298 6.9E-24 T 23-10-2018 A3L08_04955 071b7eb5f4026f3cdf88494cf29f3ff8 413 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 158 176 6.9E-24 T 23-10-2018 A3L08_04955 071b7eb5f4026f3cdf88494cf29f3ff8 413 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 248 264 6.9E-24 T 23-10-2018 A3L08_04955 071b7eb5f4026f3cdf88494cf29f3ff8 413 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 111 129 6.9E-24 T 23-10-2018 A3L08_04955 071b7eb5f4026f3cdf88494cf29f3ff8 413 Gene3D G3DSA:3.50.50.60 4 297 1.7E-53 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L08_04955 071b7eb5f4026f3cdf88494cf29f3ff8 413 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 296 5.3E-30 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A3L08_04955 071b7eb5f4026f3cdf88494cf29f3ff8 413 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 112 120 1.5E-19 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A3L08_04955 071b7eb5f4026f3cdf88494cf29f3ff8 413 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 5 27 1.5E-19 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A3L08_04955 071b7eb5f4026f3cdf88494cf29f3ff8 413 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 286 304 1.5E-19 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A3L08_04955 071b7eb5f4026f3cdf88494cf29f3ff8 413 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 206 222 1.5E-19 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A3L08_04955 071b7eb5f4026f3cdf88494cf29f3ff8 413 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 61 71 1.5E-19 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A3L08_04955 071b7eb5f4026f3cdf88494cf29f3ff8 413 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 154 178 1.5E-19 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A3L08_04955 071b7eb5f4026f3cdf88494cf29f3ff8 413 Gene3D G3DSA:3.50.50.60 123 256 1.7E-53 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L08_04955 071b7eb5f4026f3cdf88494cf29f3ff8 413 SUPERFAMILY SSF51905 1 325 3.33E-42 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A3L08_05515 91862a953b488f08a6e22244f8941f93 493 Pfam PF02386 Cation transport protein 57 480 4.9E-70 T 23-10-2018 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 A3L08_05515 91862a953b488f08a6e22244f8941f93 493 TIGRFAM TIGR00933 2a38: potassium uptake protein, TrkH family 96 469 2.0E-112 T 23-10-2018 IPR004772 TrkH potassium transport family GO:0015379|GO:0016021|GO:0071805 A3L08_07050 b0dc4c60d420674bb3258f59a3f74b83 154 Pfam PF01844 HNH endonuclease 32 74 2.6E-12 T 23-10-2018 IPR002711 HNH endonuclease GO:0003676|GO:0004519 A3L08_07050 b0dc4c60d420674bb3258f59a3f74b83 154 SMART SM00507 19 72 4.3E-10 T 23-10-2018 IPR003615 HNH nuclease A3L08_07050 b0dc4c60d420674bb3258f59a3f74b83 154 Gene3D G3DSA:3.30.40.60 4 124 8.1E-14 T 23-10-2018 A3L08_02820 79c490c6b42505ce9eb8bb46d83ac52b 438 Pfam PF13416 Bacterial extracellular solute-binding protein 81 376 1.4E-51 T 23-10-2018 IPR006059 Bacterial extracellular solute-binding protein A3L08_02820 79c490c6b42505ce9eb8bb46d83ac52b 438 ProSitePatterns PS01037 Bacterial extracellular solute-binding proteins, family 1 signature. 168 185 - T 23-10-2018 IPR006061 Solute-binding family 1, conserved site GO:0055085 A3L08_02820 79c490c6b42505ce9eb8bb46d83ac52b 438 PRINTS PR00181 Maltose binding protein signature 103 121 4.3E-12 T 23-10-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0008643|GO:0015144 A3L08_02820 79c490c6b42505ce9eb8bb46d83ac52b 438 PRINTS PR00181 Maltose binding protein signature 186 205 4.3E-12 T 23-10-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0008643|GO:0015144 A3L08_02820 79c490c6b42505ce9eb8bb46d83ac52b 438 PRINTS PR00181 Maltose binding protein signature 392 411 4.3E-12 T 23-10-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0008643|GO:0015144 A3L08_02820 79c490c6b42505ce9eb8bb46d83ac52b 438 PRINTS PR00181 Maltose binding protein signature 165 184 4.3E-12 T 23-10-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0008643|GO:0015144 A3L08_02820 79c490c6b42505ce9eb8bb46d83ac52b 438 PRINTS PR00181 Maltose binding protein signature 263 282 4.3E-12 T 23-10-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0008643|GO:0015144 A3L08_02820 79c490c6b42505ce9eb8bb46d83ac52b 438 Gene3D G3DSA:3.40.190.10 66 392 2.3E-139 T 23-10-2018 A3L08_02820 79c490c6b42505ce9eb8bb46d83ac52b 438 Gene3D G3DSA:3.40.190.10 173 407 2.3E-139 T 23-10-2018 A3L08_02820 79c490c6b42505ce9eb8bb46d83ac52b 438 SUPERFAMILY SSF53850 60 431 1.99E-93 T 23-10-2018 A3L08_01645 4816f4e9a97ac0961817858b665c1a09 183 PIRSF PIRSF006006 1 178 6.8E-86 T 23-10-2018 IPR007501 Protein of unknown function DUF531 A3L08_01645 4816f4e9a97ac0961817858b665c1a09 183 Pfam PF04407 Protein of unknown function (DUF531) 1 169 6.0E-78 T 23-10-2018 IPR007501 Protein of unknown function DUF531 A3L08_03120 220a5189bb5ef99a7d1bbddfa3029fbb 294 Gene3D G3DSA:3.90.550.10 1 229 2.2E-52 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L08_03120 220a5189bb5ef99a7d1bbddfa3029fbb 294 Pfam PF00535 Glycosyl transferase family 2 5 164 5.3E-28 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A3L08_03120 220a5189bb5ef99a7d1bbddfa3029fbb 294 SUPERFAMILY SSF53448 4 233 1.93E-40 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L08_05730 069c55849a0a9f171c6a30bb65ee63e4 206 SUPERFAMILY SSF160975 23 199 1.24E-90 T 23-10-2018 A3L08_05730 069c55849a0a9f171c6a30bb65ee63e4 206 Gene3D G3DSA:1.10.150.280 93 190 4.9E-42 T 23-10-2018 A3L08_05730 069c55849a0a9f171c6a30bb65ee63e4 206 Gene3D G3DSA:2.40.50.140 23 92 1.4E-21 T 23-10-2018 A3L08_05730 069c55849a0a9f171c6a30bb65ee63e4 206 Pfam PF04919 Protein of unknown function (DUF655) 23 198 8.7E-68 T 23-10-2018 IPR007003 Protein of unknown function DUF655 A3L08_03780 0c611bb1c8e6ce11270924384b52e224 99 Gene3D G3DSA:1.10.10.10 1 98 2.6E-23 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L08_03780 0c611bb1c8e6ce11270924384b52e224 99 SUPERFAMILY SSF46785 3 96 1.68E-25 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L08_03780 0c611bb1c8e6ce11270924384b52e224 99 Pfam PF03551 Transcriptional regulator PadR-like family 14 84 3.0E-15 T 23-10-2018 IPR005149 Transcription regulator PadR, N-terminal A3L08_01555 5e63f01a5d856e6fd853b7cfb0ab3d8f 224 TIGRFAM TIGR00659 TIGR00659: TIGR00659 family protein 6 223 1.2E-78 T 23-10-2018 IPR005261 Conserved hypothetical protein CHP00659 A3L08_01555 5e63f01a5d856e6fd853b7cfb0ab3d8f 224 Pfam PF04172 LrgB-like family 9 221 8.1E-72 T 23-10-2018 IPR007300 CidB/LrgB family A3L08_07625 3163541649106aacc29fbb84c14d718a 108 SUPERFAMILY SSF51182 2 102 3.13E-22 T 23-10-2018 IPR011051 RmlC-like cupin domain superfamily A3L08_07625 3163541649106aacc29fbb84c14d718a 108 Gene3D G3DSA:2.60.120.10 2 104 1.7E-29 T 23-10-2018 IPR014710 RmlC-like jelly roll fold A3L08_07625 3163541649106aacc29fbb84c14d718a 108 Pfam PF07883 Cupin domain 40 90 8.9E-11 T 23-10-2018 IPR013096 Cupin 2, conserved barrel A3L08_02280 e890269ef0c61a2871fb2b1ca8dc7e94 247 Gene3D G3DSA:3.40.50.300 3 247 6.5E-71 T 23-10-2018 A3L08_05565 66aa4d725a40337f30d21c8506f71301 224 SUPERFAMILY SSF159612 2 218 3.14E-108 T 23-10-2018 A3L08_05565 66aa4d725a40337f30d21c8506f71301 224 Gene3D G3DSA:3.90.79.30 101 220 3.7E-59 T 23-10-2018 A3L08_05565 66aa4d725a40337f30d21c8506f71301 224 Pfam PF15517 TBP-interacting protein N-terminus 3 102 4.4E-44 T 23-10-2018 IPR029125 TBP-interacting protein, N-terminal A3L08_05565 66aa4d725a40337f30d21c8506f71301 224 Gene3D G3DSA:3.40.1350.70 1 100 3.3E-47 T 23-10-2018 IPR038230 TBP-interacting protein, N-terminal superfamily A3L08_04840 1f6d73afa3de40cc8bc667c4863ee385 155 Gene3D G3DSA:2.70.40.10 1 155 5.7E-43 T 23-10-2018 IPR036157 dUTPase-like superfamily A3L08_04840 1f6d73afa3de40cc8bc667c4863ee385 155 TIGRFAM TIGR02274 dCTP_deam: deoxycytidine triphosphate deaminase 9 152 5.3E-47 T 23-10-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 A3L08_04840 1f6d73afa3de40cc8bc667c4863ee385 155 Hamap MF_00146 dCTP deaminase [dcd]. 1 153 27.731 T 23-10-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 A3L08_04840 1f6d73afa3de40cc8bc667c4863ee385 155 Pfam PF00692 dUTPase 46 139 2.6E-14 T 23-10-2018 IPR029054 dUTPase-like A3L08_04840 1f6d73afa3de40cc8bc667c4863ee385 155 SUPERFAMILY SSF51283 1 153 4.06E-40 T 23-10-2018 IPR036157 dUTPase-like superfamily A3L08_05825 c6a03e580931efad4e6043e002076400 459 SUPERFAMILY SSF161070 78 369 5.89E-5 T 23-10-2018 IPR037272 Sodium:neurotransmitter symporter superfamily GO:0005328 A3L08_04190 f0ab6ab4f44dff3dbae3901a4ee55f37 83 Hamap MF_00721 50S ribosomal protein L14e [rpl14e]. 1 79 26.494 T 23-10-2018 IPR023651 Ribosomal protein L14e GO:0003735|GO:0005840|GO:0006412 A3L08_04190 f0ab6ab4f44dff3dbae3901a4ee55f37 83 Gene3D G3DSA:2.30.30.30 2 83 1.4E-29 T 23-10-2018 IPR014722 Ribosomal protein L2, domain 2 A3L08_04190 f0ab6ab4f44dff3dbae3901a4ee55f37 83 SUPERFAMILY SSF50104 2 80 5.92E-20 T 23-10-2018 IPR008991 Translation protein SH3-like domain superfamily A3L08_04190 f0ab6ab4f44dff3dbae3901a4ee55f37 83 Pfam PF01929 Ribosomal protein L14 44 81 1.3E-4 T 23-10-2018 IPR002784 Ribosomal protein L14e domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_02340 4f4b4e21b686519635a4604630dae4a1 181 TIGRFAM TIGR00455 apsK: adenylyl-sulfate kinase 5 171 2.4E-68 T 23-10-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 A3L08_02340 4f4b4e21b686519635a4604630dae4a1 181 Hamap MF_00065 Adenylyl-sulfate kinase [cysC]. 8 178 37.199 T 23-10-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 A3L08_02340 4f4b4e21b686519635a4604630dae4a1 181 Gene3D G3DSA:3.40.50.300 4 181 4.0E-61 T 23-10-2018 A3L08_02340 4f4b4e21b686519635a4604630dae4a1 181 Pfam PF01583 Adenylylsulphate kinase 9 160 1.8E-60 T 23-10-2018 A3L08_02340 4f4b4e21b686519635a4604630dae4a1 181 SUPERFAMILY SSF52540 6 176 7.21E-37 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_01750 ba616b3c4b04ef7b53b76146af8107dd 87 Pfam PF13244 Domain of unknown function (DUF4040) 17 82 2.8E-17 T 23-10-2018 IPR025383 Domain of unknown function DUF4040 A3L08_07440 0656812422b829b9f804b864a1b8bc3d 498 SUPERFAMILY SSF56300 256 485 9.64E-34 T 23-10-2018 A3L08_07440 0656812422b829b9f804b864a1b8bc3d 498 Gene3D G3DSA:3.60.21.10 254 491 2.4E-22 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like A3L08_07440 0656812422b829b9f804b864a1b8bc3d 498 Gene3D G3DSA:3.60.21.10 1 253 1.3E-39 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like A3L08_07440 0656812422b829b9f804b864a1b8bc3d 498 SUPERFAMILY SSF56300 1 234 7.32E-50 T 23-10-2018 A3L08_07440 0656812422b829b9f804b864a1b8bc3d 498 Pfam PF00149 Calcineurin-like phosphoesterase 1 184 3.3E-21 T 23-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 A3L08_07440 0656812422b829b9f804b864a1b8bc3d 498 Pfam PF00149 Calcineurin-like phosphoesterase 275 433 7.9E-8 T 23-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 A3L08_09085 38a6ca775bab681a2b15ef9e7a2b72a2 203 Gene3D G3DSA:1.20.1540.10 4 197 1.2E-36 T 23-10-2018 IPR035952 Rhomboid-like superfamily A3L08_09085 38a6ca775bab681a2b15ef9e7a2b72a2 203 SUPERFAMILY SSF144091 8 193 1.7E-38 T 23-10-2018 A3L08_09085 38a6ca775bab681a2b15ef9e7a2b72a2 203 Pfam PF01694 Rhomboid family 55 189 2.0E-31 T 23-10-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 A3L08_08685 0195b46d1d68587b4f0f8fa404d3b123 381 Gene3D G3DSA:1.10.4080.10 49 360 1.4E-52 T 23-10-2018 IPR036705 ADP-ribosylation/Crystallin J1 superfamily A3L08_08685 0195b46d1d68587b4f0f8fa404d3b123 381 SUPERFAMILY SSF101478 51 358 2.88E-51 T 23-10-2018 IPR036705 ADP-ribosylation/Crystallin J1 superfamily A3L08_08685 0195b46d1d68587b4f0f8fa404d3b123 381 Pfam PF03747 ADP-ribosylglycohydrolase 56 340 7.0E-50 T 23-10-2018 IPR005502 ADP-ribosylation/Crystallin J1 A3L08_09300 4e990feea3b3593b4a4634d9ad5fa877 273 SUPERFAMILY SSF53686 3 270 6.42E-65 T 23-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme A3L08_09300 4e990feea3b3593b4a4634d9ad5fa877 273 Gene3D G3DSA:3.40.50.1100 3 263 3.0E-72 T 23-10-2018 A3L08_09300 4e990feea3b3593b4a4634d9ad5fa877 273 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 3 257 2.8E-47 T 23-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme A3L08_09300 4e990feea3b3593b4a4634d9ad5fa877 273 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 5 24 - T 23-10-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 A3L08_09300 4e990feea3b3593b4a4634d9ad5fa877 273 Gene3D G3DSA:3.40.50.1100 19 120 3.0E-72 T 23-10-2018 A3L08_01185 b2274594f95784576b559e5229943bb4 453 Pfam PF01523 Putative modulator of DNA gyrase 19 307 1.3E-65 T 23-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 A3L08_01185 b2274594f95784576b559e5229943bb4 453 Gene3D G3DSA:3.30.2290.10 1 188 9.6E-16 T 23-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal A3L08_01185 b2274594f95784576b559e5229943bb4 453 PIRSF PIRSF004919 1 453 1.8E-161 T 23-10-2018 IPR025502 TldD A3L08_01185 b2274594f95784576b559e5229943bb4 453 SUPERFAMILY SSF111283 2 447 3.4E-114 T 23-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 A3L08_05885 019445bf541d2e164faa0a7301aa2242 310 Gene3D G3DSA:1.20.1420.30 38 298 9.9E-76 T 23-10-2018 A3L08_05885 019445bf541d2e164faa0a7301aa2242 310 Pfam PF01699 Sodium/calcium exchanger protein 168 304 2.5E-23 T 23-10-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 A3L08_05885 019445bf541d2e164faa0a7301aa2242 310 Pfam PF01699 Sodium/calcium exchanger protein 10 145 1.2E-20 T 23-10-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 A3L08_05885 019445bf541d2e164faa0a7301aa2242 310 Gene3D G3DSA:1.20.58.1130 12 198 9.9E-76 T 23-10-2018 A3L08_02525 cd88e07721c3f29b37fe7c54a9b83853 175 Pfam PF03692 Putative zinc- or iron-chelating domain 15 126 4.5E-16 T 23-10-2018 IPR005358 Putative zinc- or iron-chelating domain containing protein A3L08_08770 958fd9225dd5eaf5e0ec619ac7c6b676 334 Gene3D G3DSA:3.40.50.720 4 317 2.0E-141 T 23-10-2018 A3L08_08770 958fd9225dd5eaf5e0ec619ac7c6b676 334 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 230 246 - T 23-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site A3L08_08770 958fd9225dd5eaf5e0ec619ac7c6b676 334 SUPERFAMILY SSF51735 103 290 1.6E-66 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A3L08_08770 958fd9225dd5eaf5e0ec619ac7c6b676 334 Hamap MF_00776 Glyoxylate reductase [gyaR]. 1 331 60.88 T 23-10-2018 IPR023519 Glyoxylate reductase GyaR GO:0047964|GO:0055114 KEGG: 00630+1.1.1.26|MetaCyc: PWY-7294|MetaCyc: PWY-7295 A3L08_08770 958fd9225dd5eaf5e0ec619ac7c6b676 334 Gene3D G3DSA:3.40.50.720 98 290 2.0E-141 T 23-10-2018 A3L08_08770 958fd9225dd5eaf5e0ec619ac7c6b676 334 SUPERFAMILY SSF52283 2 133 2.08E-42 T 23-10-2018 A3L08_08770 958fd9225dd5eaf5e0ec619ac7c6b676 334 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 5 322 1.0E-37 T 23-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 A3L08_08770 958fd9225dd5eaf5e0ec619ac7c6b676 334 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 110 290 9.1E-68 T 23-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 A3L08_01740 598651fbaf52689e536d29950e015ea3 87 Pfam PF04066 Multiple resistance and pH regulation protein F (MrpF / PhaF) 31 82 1.2E-21 T 23-10-2018 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 A3L08_09610 fe763acb5015e1a903ae42aba64ad3d5 223 Gene3D G3DSA:3.60.110.10 1 220 9.1E-34 T 23-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily A3L08_09610 fe763acb5015e1a903ae42aba64ad3d5 223 SUPERFAMILY SSF56317 1 217 2.22E-38 T 23-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily A3L08_09610 fe763acb5015e1a903ae42aba64ad3d5 223 Pfam PF00795 Carbon-nitrogen hydrolase 2 165 1.0E-16 T 23-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 A3L08_07495 43560a8446c865665995556a2f716bec 148 Gene3D G3DSA:3.40.50.1000 5 142 5.2E-10 T 23-10-2018 IPR023214 HAD superfamily A3L08_07495 43560a8446c865665995556a2f716bec 148 SUPERFAMILY SSF56784 11 130 1.68E-11 T 23-10-2018 IPR036412 HAD-like superfamily A3L08_04460 7a7c3d6ebe80daa6ecc20e46a92e6b99 151 SUPERFAMILY SSF55282 7 149 1.24E-40 T 23-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_04460 7a7c3d6ebe80daa6ecc20e46a92e6b99 151 Gene3D G3DSA:3.30.1440.10 2 149 4.1E-45 T 23-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_04460 7a7c3d6ebe80daa6ecc20e46a92e6b99 151 Pfam PF01877 RNA binding 8 131 8.7E-38 T 23-10-2018 IPR002739 Uncharacterised protein family UPF0201 A3L08_01515 7041cfa53bbc62971c95b881f8d33b83 300 PIRSF PIRSF016896 1 296 5.4E-94 T 23-10-2018 IPR012043 Pantoate kinase KEGG: 00770+2.7.1.169|MetaCyc: PWY-6654 A3L08_01515 7041cfa53bbc62971c95b881f8d33b83 300 SUPERFAMILY SSF54211 1 156 5.09E-13 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A3L08_01515 7041cfa53bbc62971c95b881f8d33b83 300 Gene3D G3DSA:3.30.230.10 26 162 1.9E-5 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A3L08_01515 7041cfa53bbc62971c95b881f8d33b83 300 Pfam PF00288 GHMP kinases N terminal domain 93 151 1.4E-6 T 23-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 A3L08_08935 c71a1b6ffbf018aacd9b9395dc6225aa 253 Pfam PF02361 Cobalt transport protein 11 204 1.6E-27 T 23-10-2018 IPR003339 ABC/ECF transporter, transmembrane component A3L08_07915 17e20dc2f86a5bdd52de5020e266b1ed 398 Pfam PF03222 Tryptophan/tyrosine permease family 68 396 6.1E-26 T 23-10-2018 IPR018227 Amino acid/polyamine transporter 2 GO:0003333 A3L08_07815 75c573c31a9b7e3e85e5ee2289cdcf4a 242 SUPERFAMILY SSF55486 174 220 6.36E-9 T 23-10-2018 A3L08_07815 75c573c31a9b7e3e85e5ee2289cdcf4a 242 Gene3D G3DSA:3.40.390.10 75 228 2.9E-18 T 23-10-2018 IPR024079 Metallopeptidase, catalytic domain superfamily GO:0008237 A3L08_07815 75c573c31a9b7e3e85e5ee2289cdcf4a 242 Pfam PF07998 Peptidase family M54 164 223 2.1E-22 T 23-10-2018 IPR012962 Peptidase M54, archaemetzincin GO:0008270 A3L08_07815 75c573c31a9b7e3e85e5ee2289cdcf4a 242 Pfam PF07998 Peptidase family M54 1 140 1.2E-19 T 23-10-2018 IPR012962 Peptidase M54, archaemetzincin GO:0008270 A3L08_08545 938c7a1260f3ec52e44420f1e034ed36 140 SUPERFAMILY SSF117856 3 129 3.4E-33 T 23-10-2018 A3L08_08545 938c7a1260f3ec52e44420f1e034ed36 140 PIRSF PIRSF016702 1 139 7.4E-44 T 23-10-2018 IPR025707 Predicted DNA-binding protein with PD1-like DNA-binding motif A3L08_08545 938c7a1260f3ec52e44420f1e034ed36 140 Gene3D G3DSA:3.30.1330.80 1 139 1.5E-47 T 23-10-2018 A3L08_08545 938c7a1260f3ec52e44420f1e034ed36 140 Pfam PF03479 Domain of unknown function (DUF296) 8 118 9.8E-19 T 23-10-2018 IPR005175 PPC domain A3L08_07550 6ebb66f1189dd0e607f5bffb4c89372d 479 SUPERFAMILY SSF103365 2 479 2.62E-185 T 23-10-2018 IPR036025 tRNA-splicing ligase RtcB-like superfamily GO:0006396|GO:0008452 Reactome: R-HSA-6784531 A3L08_07550 6ebb66f1189dd0e607f5bffb4c89372d 479 Pfam PF01139 tRNA-splicing ligase RtcB 45 479 8.8E-181 T 23-10-2018 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 A3L08_07550 6ebb66f1189dd0e607f5bffb4c89372d 479 Gene3D G3DSA:3.90.1860.10 1 479 1.4E-227 T 23-10-2018 IPR036025 tRNA-splicing ligase RtcB-like superfamily GO:0006396|GO:0008452 Reactome: R-HSA-6784531 A3L08_01680 84969f1f2e84d680187474ef89a68fe6 75 Gene3D G3DSA:3.30.70.920 1 74 8.7E-27 T 23-10-2018 A3L08_01680 84969f1f2e84d680187474ef89a68fe6 75 Pfam PF01037 Lrp/AsnC ligand binding domain 9 74 2.3E-18 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A3L08_01680 84969f1f2e84d680187474ef89a68fe6 75 SUPERFAMILY SSF54909 1 74 9.52E-18 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel A3L08_07395 c0244d97022a8ed59e9b63761eb7d473 76 Pfam PF02597 ThiS family 4 76 8.0E-9 T 23-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 A3L08_07395 c0244d97022a8ed59e9b63761eb7d473 76 Gene3D G3DSA:3.10.20.30 1 76 4.4E-14 T 23-10-2018 IPR012675 Beta-grasp domain superfamily A3L08_07395 c0244d97022a8ed59e9b63761eb7d473 76 SUPERFAMILY SSF54285 1 76 6.35E-11 T 23-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp A3L08_08275 09b7ec3c59fa8ea0ecab049f3799fe2a 823 SUPERFAMILY SSF52317 560 691 3.36E-8 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A3L08_08275 09b7ec3c59fa8ea0ecab049f3799fe2a 823 Pfam PF10131 6-pyruvoyl-tetrahydropterin synthase related domain; membrane protein 70 690 5.1E-61 T 23-10-2018 IPR018776 Membrane protein, 6-pyruvoyl-tetrahydropterin synthase-related domain A3L08_08275 09b7ec3c59fa8ea0ecab049f3799fe2a 823 Gene3D G3DSA:3.40.50.880 544 703 7.1E-9 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A3L08_06050 ace4abcf3e8301570220b1fc6cdf31ca 86 Hamap MF_00327 50S ribosomal protein L37Ae [rpl37ae]. 3 71 25.07 T 23-10-2018 IPR002674 Ribosomal protein L37ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L08_06050 ace4abcf3e8301570220b1fc6cdf31ca 86 Pfam PF01780 Ribosomal L37ae protein family 3 82 1.1E-33 T 23-10-2018 IPR002674 Ribosomal protein L37ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L08_06050 ace4abcf3e8301570220b1fc6cdf31ca 86 TIGRFAM TIGR00280 eL43_euk_arch: ribosomal protein eL43 1 80 8.0E-37 T 23-10-2018 IPR002674 Ribosomal protein L37ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L08_06050 ace4abcf3e8301570220b1fc6cdf31ca 86 Gene3D G3DSA:2.20.25.30 9 86 8.4E-32 T 23-10-2018 IPR011331 Ribosomal protein L37ae/L37e GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L08_06050 ace4abcf3e8301570220b1fc6cdf31ca 86 SUPERFAMILY SSF57829 10 80 1.34E-28 T 23-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 A3L08_05775 984412ab9fff42ab80e9a196fd121730 407 Pfam PF00534 Glycosyl transferases group 1 195 365 5.6E-25 T 23-10-2018 IPR001296 Glycosyl transferase, family 1 A3L08_05775 984412ab9fff42ab80e9a196fd121730 407 Gene3D G3DSA:3.40.50.2000 183 372 1.5E-73 T 23-10-2018 A3L08_05775 984412ab9fff42ab80e9a196fd121730 407 Pfam PF13439 Glycosyltransferase Family 4 17 185 1.5E-25 T 23-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 A3L08_05775 984412ab9fff42ab80e9a196fd121730 407 SUPERFAMILY SSF53756 5 384 4.93E-73 T 23-10-2018 A3L08_05775 984412ab9fff42ab80e9a196fd121730 407 Gene3D G3DSA:3.40.50.2000 8 373 1.5E-73 T 23-10-2018 A3L08_00565 6106c8fe91c386962de7ffc83023ef54 280 SUPERFAMILY SSF102114 10 189 4.45E-17 T 23-10-2018 A3L08_00565 6106c8fe91c386962de7ffc83023ef54 280 Pfam PF04055 Radical SAM superfamily 23 187 2.7E-17 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L08_00565 6106c8fe91c386962de7ffc83023ef54 280 SMART SM00729 18 225 2.0E-11 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A3L08_00565 6106c8fe91c386962de7ffc83023ef54 280 Gene3D G3DSA:3.80.30.30 50 255 3.7E-13 T 23-10-2018 A3L08_01685 c6a7348cd23a50e9e9283e8f0bdfa255 393 Gene3D G3DSA:1.10.3720.10 176 389 3.7E-18 T 23-10-2018 IPR035906 MetI-like superfamily A3L08_01685 c6a7348cd23a50e9e9283e8f0bdfa255 393 SUPERFAMILY SSF161098 181 379 1.96E-18 T 23-10-2018 IPR035906 MetI-like superfamily A3L08_01685 c6a7348cd23a50e9e9283e8f0bdfa255 393 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 203 380 5.6E-14 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A3L08_07890 1261606dde9a268bccdd0fb19e210263 216 SUPERFAMILY SSF48317 30 204 2.22E-31 T 23-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily A3L08_07890 1261606dde9a268bccdd0fb19e210263 216 Gene3D G3DSA:1.20.144.10 108 206 2.4E-17 T 23-10-2018 A3L08_07890 1261606dde9a268bccdd0fb19e210263 216 Pfam PF01569 PAP2 superfamily 83 190 6.1E-19 T 23-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase A3L08_07890 1261606dde9a268bccdd0fb19e210263 216 SMART SM00014 81 191 5.3E-11 T 23-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase A3L08_00445 a826c9172073c393581da6600ba28999 334 Pfam PF04122 Putative cell wall binding repeat 2 114 191 4.7E-6 T 23-10-2018 IPR007253 Putative cell wall binding repeat 2 A3L08_00445 a826c9172073c393581da6600ba28999 334 SUPERFAMILY SSF46785 266 330 1.49E-10 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L08_00445 a826c9172073c393581da6600ba28999 334 Gene3D G3DSA:1.10.10.10 266 330 2.6E-9 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L08_06990 87e4e27d7507dfce24a44bfbf26ee117 163 SUPERFAMILY SSF88723 3 143 5.33E-24 T 23-10-2018 IPR029060 PIN-like domain superfamily A3L08_06990 87e4e27d7507dfce24a44bfbf26ee117 163 Gene3D G3DSA:3.40.50.1010 1 146 1.3E-34 T 23-10-2018 A3L08_08210 06ccc3ab0c728899a2a280bf07e04420 286 SUPERFAMILY SSF53613 1 282 1.06E-63 T 23-10-2018 IPR029056 Ribokinase-like A3L08_08210 06ccc3ab0c728899a2a280bf07e04420 286 Pfam PF00294 pfkB family carbohydrate kinase 2 281 6.0E-51 T 23-10-2018 IPR011611 Carbohydrate kinase PfkB A3L08_08210 06ccc3ab0c728899a2a280bf07e04420 286 Gene3D G3DSA:3.40.1190.20 2 285 1.6E-68 T 23-10-2018 IPR029056 Ribokinase-like A3L08_02335 6e95d3922b97c00f923b0d28d1ada345 245 Pfam PF01925 Sulfite exporter TauE/SafE 6 239 1.9E-40 T 23-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 A3L08_01215 4afe9807528c92987d50c08f1c072251 648 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 69 178 9.2E-14 T 23-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 A3L08_01215 4afe9807528c92987d50c08f1c072251 648 Gene3D G3DSA:3.30.230.10 32 226 7.4E-29 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A3L08_01215 4afe9807528c92987d50c08f1c072251 648 SUPERFAMILY SSF54211 49 230 1.02E-25 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A3L08_01215 4afe9807528c92987d50c08f1c072251 648 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 140 159 7.2E-8 T 23-10-2018 A3L08_01215 4afe9807528c92987d50c08f1c072251 648 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 163 181 7.2E-8 T 23-10-2018 A3L08_01215 4afe9807528c92987d50c08f1c072251 648 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 110 129 7.2E-8 T 23-10-2018 A3L08_00630 10957239696f16b8092b2afe371e2462 538 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 33 435 4.9E-78 T 23-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 A3L08_00630 10957239696f16b8092b2afe371e2462 538 Pfam PF00474 Sodium:solute symporter family 33 435 1.6E-83 T 23-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 A3L08_00630 10957239696f16b8092b2afe371e2462 538 Gene3D G3DSA:1.20.1730.10 22 515 1.1E-90 T 23-10-2018 IPR038377 Sodium/glucose symporter superfamily A3L08_08670 2a6ff91e9759789933921314b6dbfb36 322 SUPERFAMILY SSF56235 2 190 1.16E-26 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A3L08_08670 2a6ff91e9759789933921314b6dbfb36 322 Gene3D G3DSA:3.60.20.10 1 260 1.1E-70 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A3L08_08670 2a6ff91e9759789933921314b6dbfb36 322 Pfam PF13230 Glutamine amidotransferases class-II 1 263 1.1E-68 T 23-10-2018 IPR026869 Putative glutamine amidotransferase type 2 A3L08_04860 45be070c4ba309b31191266973684e5c 133 Hamap MF_01095 UPF0292 protein . 3 123 33.106 T 23-10-2018 IPR022972 Uncharacterised protein family UPF0292 A3L08_04860 45be070c4ba309b31191266973684e5c 133 Gene3D G3DSA:3.40.1360.10 3 116 2.3E-22 T 23-10-2018 A3L08_04860 45be070c4ba309b31191266973684e5c 133 SMART SM00493 20 90 1.1E-6 T 23-10-2018 IPR006171 TOPRIM domain A3L08_04860 45be070c4ba309b31191266973684e5c 133 Pfam PF01751 Toprim domain 51 86 1.4E-6 T 23-10-2018 IPR006171 TOPRIM domain A3L08_04860 45be070c4ba309b31191266973684e5c 133 SUPERFAMILY SSF110455 19 91 5.36E-6 T 23-10-2018 A3L08_03110 4d6297d1f439ef566c6f3d4382e6b4ab 405 SUPERFAMILY SSF53448 40 300 4.42E-47 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L08_03110 4d6297d1f439ef566c6f3d4382e6b4ab 405 Pfam PF00535 Glycosyl transferase family 2 47 185 4.3E-27 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A3L08_03110 4d6297d1f439ef566c6f3d4382e6b4ab 405 Gene3D G3DSA:3.90.550.10 32 266 5.7E-36 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L08_03015 bb04908d3dc69f171841a388bac9119c 333 Pfam PF07760 Protein of unknown function (DUF1616) 15 302 1.6E-93 T 23-10-2018 IPR011674 Domain of unknown function DUF1616 A3L08_03015 bb04908d3dc69f171841a388bac9119c 333 PIRSF PIRSF018671 2 333 9.9E-121 T 23-10-2018 IPR014495 Uncharacterised conserved protein UCP018671 A3L08_08120 8ef8018ef0c4dccc279a2c03625da757 363 Pfam PF03600 Citrate transporter 13 300 1.1E-23 T 23-10-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 A3L08_01550 e9ddcaed2720af8382f2daf76d225a5a 115 Pfam PF03788 LrgA family 15 106 2.0E-29 T 23-10-2018 IPR005538 LrgA/CidA family GO:0016021 A3L08_02730 c59e4cc88c5eb862dd587ff0668d07f5 413 SUPERFAMILY SSF140914 2 249 1.06E-21 T 23-10-2018 A3L08_02730 c59e4cc88c5eb862dd587ff0668d07f5 413 Hamap MF_00701 DNA primase large subunit PriL [priL]. 1 389 27.099 T 23-10-2018 IPR023642 DNA primase large subunit PriL GO:0003896 A3L08_02730 c59e4cc88c5eb862dd587ff0668d07f5 413 Gene3D G3DSA:1.20.930.50 9 224 3.6E-43 T 23-10-2018 A3L08_02730 c59e4cc88c5eb862dd587ff0668d07f5 413 Gene3D G3DSA:2.20.20.80 109 171 3.6E-43 T 23-10-2018 A3L08_02730 c59e4cc88c5eb862dd587ff0668d07f5 413 Pfam PF04104 Eukaryotic and archaeal DNA primase, large subunit 143 362 3.3E-28 T 23-10-2018 IPR007238 DNA primase large subunit, eukaryotic/archaeal GO:0003896|GO:0006269 Reactome: R-HSA-113501|Reactome: R-HSA-174411|Reactome: R-HSA-174430|Reactome: R-HSA-68952|Reactome: R-HSA-68962|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183 A3L08_03540 9c998a71cd89a529735fa297343f12e4 213 Pfam PF04254 Protein of unknown function (DUF432) 51 165 1.7E-28 T 23-10-2018 IPR007366 Protein of unknown function DUF432 A3L08_03540 9c998a71cd89a529735fa297343f12e4 213 PIRSF PIRSF019202 1 213 9.9E-51 T 23-10-2018 IPR007366 Protein of unknown function DUF432 A3L08_04115 83254964860b4543cdf1752f57c365bf 183 PIRSF PIRSF002161 2 180 9.1E-55 T 23-10-2018 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_04115 83254964860b4543cdf1752f57c365bf 183 SUPERFAMILY SSF55282 15 178 6.12E-56 T 23-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_04115 83254964860b4543cdf1752f57c365bf 183 Pfam PF00673 ribosomal L5P family C-terminus 72 171 3.4E-26 T 23-10-2018 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_04115 83254964860b4543cdf1752f57c365bf 183 Hamap MF_01333_A 50S ribosomal protein L5 [rplE]. 14 181 41.157 T 23-10-2018 IPR022804 Ribosomal protein L5, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L08_04115 83254964860b4543cdf1752f57c365bf 183 Gene3D G3DSA:3.30.1440.10 10 181 6.2E-70 T 23-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_04115 83254964860b4543cdf1752f57c365bf 183 Pfam PF00281 Ribosomal protein L5 16 68 5.1E-19 T 23-10-2018 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_08180 22374f9388d3c2b722e1893b42216b3a 117 Pfam PF03625 Domain of unknown function DUF302 39 94 1.1E-17 T 23-10-2018 IPR005180 Domain of unknown function DUF302 A3L08_08180 22374f9388d3c2b722e1893b42216b3a 117 SUPERFAMILY SSF103247 4 116 8.5E-27 T 23-10-2018 IPR035923 TT1751-like domain superfamily A3L08_08180 22374f9388d3c2b722e1893b42216b3a 117 PIRSF PIRSF021774 1 117 1.8E-25 T 23-10-2018 IPR016796 Uncharacterised conserved protein UCP021774 A3L08_08180 22374f9388d3c2b722e1893b42216b3a 117 Gene3D G3DSA:3.30.310.70 1 117 2.4E-25 T 23-10-2018 IPR035923 TT1751-like domain superfamily A3L08_09510 d2014e975ca6a7e23e7ee4788a1952d1 562 Gene3D G3DSA:3.20.20.240 1 562 1.6E-270 T 23-10-2018 A3L08_09510 d2014e975ca6a7e23e7ee4788a1952d1 562 SUPERFAMILY SSF51703 9 556 3.53E-232 T 23-10-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 A3L08_09510 d2014e975ca6a7e23e7ee4788a1952d1 562 Pfam PF01642 Methylmalonyl-CoA mutase 39 554 8.2E-242 T 23-10-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 A3L08_09510 d2014e975ca6a7e23e7ee4788a1952d1 562 TIGRFAM TIGR00641 acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain 37 560 1.1E-291 T 23-10-2018 IPR006098 Methylmalonyl-CoA mutase, alpha chain, catalytic GO:0004494|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 A3L08_03600 c9cb3776d2763d9065135d1456acbf1e 355 Gene3D G3DSA:3.40.50.300 14 214 4.4E-26 T 23-10-2018 A3L08_03600 c9cb3776d2763d9065135d1456acbf1e 355 Pfam PF16575 mRNA cleavage and polyadenylation factor CLP1 P-loop 34 209 4.4E-41 T 23-10-2018 IPR032319 Polyribonucleotide 5'-hydroxyl-kinase Clp1, P-loop domain A3L08_03600 c9cb3776d2763d9065135d1456acbf1e 355 SUPERFAMILY SSF52540 29 162 2.55E-12 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_09295 38a2f414cf04c4fa657f707949f572d5 196 SUPERFAMILY SSF52402 2 156 1.87E-39 T 23-10-2018 A3L08_09295 38a2f414cf04c4fa657f707949f572d5 196 Pfam PF02568 Thiamine biosynthesis protein (ThiI) 2 188 1.9E-57 T 23-10-2018 IPR020536 Thil, AANH domain GO:0004810 KEGG: 00730+2.8.1.4 A3L08_09295 38a2f414cf04c4fa657f707949f572d5 196 Gene3D G3DSA:3.40.50.620 1 195 8.5E-56 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L08_05240 2a546e85555c35e7649e04905ca3f84a 157 Gene3D G3DSA:3.40.50.620 1 157 6.2E-52 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A3L08_05240 2a546e85555c35e7649e04905ca3f84a 157 SUPERFAMILY SSF52402 2 154 6.11E-26 T 23-10-2018 A3L08_05240 2a546e85555c35e7649e04905ca3f84a 157 PRINTS PR01438 Universal stress protein signature 2 20 1.9E-12 T 23-10-2018 IPR006015 Universal stress protein A A3L08_05240 2a546e85555c35e7649e04905ca3f84a 157 PRINTS PR01438 Universal stress protein signature 112 124 1.9E-12 T 23-10-2018 IPR006015 Universal stress protein A A3L08_05240 2a546e85555c35e7649e04905ca3f84a 157 PRINTS PR01438 Universal stress protein signature 130 152 1.9E-12 T 23-10-2018 IPR006015 Universal stress protein A A3L08_05240 2a546e85555c35e7649e04905ca3f84a 157 Pfam PF00582 Universal stress protein family 1 152 1.5E-23 T 23-10-2018 IPR006016 UspA A3L08_07730 cdf1034ea9e84908d92713e30c3b974a 455 Gene3D G3DSA:3.30.2290.10 1 216 4.4E-16 T 23-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal A3L08_07730 cdf1034ea9e84908d92713e30c3b974a 455 SUPERFAMILY SSF111283 2 450 1.12E-96 T 23-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 A3L08_07730 cdf1034ea9e84908d92713e30c3b974a 455 Pfam PF01523 Putative modulator of DNA gyrase 19 310 2.5E-45 T 23-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 A3L08_07730 cdf1034ea9e84908d92713e30c3b974a 455 PIRSF PIRSF004919 1 455 1.2E-157 T 23-10-2018 IPR025502 TldD A3L08_00260 4b4edf393e18c170c56bb1663cccd9ce 269 Pfam PF02535 ZIP Zinc transporter 124 264 4.9E-21 T 23-10-2018 IPR003689 Zinc/iron permease GO:0016020|GO:0030001|GO:0046873|GO:0055085 A3L08_08520 315a69f1c4e4a6085e127aa06c2a44e9 143 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 13 106 7.1E-23 T 23-10-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis A3L08_08520 315a69f1c4e4a6085e127aa06c2a44e9 143 Gene3D G3DSA:3.30.420.130 1 114 2.4E-31 T 23-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily A3L08_08520 315a69f1c4e4a6085e127aa06c2a44e9 143 SUPERFAMILY SSF53146 1 113 4.71E-31 T 23-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily A3L08_03410 a2823ed318e927051aa274955a0bb879 197 Pfam PF06510 Protein of unknown function (DUF1102) 39 185 5.3E-56 T 23-10-2018 IPR009482 Protein of unknown function DUF1102 A3L08_06625 ab7d8ce4d24fc918730fcb3502b46c3a 289 SUPERFAMILY SSF103481 47 145 1.57E-12 T 23-10-2018 A3L08_06625 ab7d8ce4d24fc918730fcb3502b46c3a 289 SUPERFAMILY SSF103481 198 287 4.05E-11 T 23-10-2018 A3L08_06625 ab7d8ce4d24fc918730fcb3502b46c3a 289 Pfam PF00892 EamA-like transporter family 6 141 2.2E-20 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A3L08_06625 ab7d8ce4d24fc918730fcb3502b46c3a 289 Pfam PF00892 EamA-like transporter family 153 288 1.2E-21 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A3L08_05375 61d8cab7868e73b8278347513c9c18f5 378 Pfam PF01513 ATP-NAD kinase 2 376 3.7E-48 T 23-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 A3L08_05375 61d8cab7868e73b8278347513c9c18f5 378 PIRSF PIRSF016907 1 378 9.6E-147 T 23-10-2018 IPR011386 Putative ATP-NAD kinase A3L08_05375 61d8cab7868e73b8278347513c9c18f5 378 SUPERFAMILY SSF111331 99 173 3.76E-6 T 23-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily A3L08_02840 ec12d600195fadd53698fdd71c7328fd 120 Pfam PF01900 Rpp14/Pop5 family 17 113 6.8E-23 T 23-10-2018 IPR002759 Ribonuclease P/MRP protein subunit GO:0004540|GO:0008033 Reactome: R-HSA-6784531 A3L08_02840 ec12d600195fadd53698fdd71c7328fd 120 PIRSF PIRSF004952 4 120 3.3E-47 T 23-10-2018 IPR016434 Ribonuclease P, protein component 2 GO:0001682|GO:0004526 A3L08_02840 ec12d600195fadd53698fdd71c7328fd 120 SUPERFAMILY SSF160350 4 116 3.79E-35 T 23-10-2018 IPR038085 Rnp2-like domain superfamily Reactome: R-HSA-6784531 A3L08_02840 ec12d600195fadd53698fdd71c7328fd 120 Gene3D G3DSA:3.30.70.3250 1 120 2.1E-49 T 23-10-2018 IPR038085 Rnp2-like domain superfamily Reactome: R-HSA-6784531 A3L08_02840 ec12d600195fadd53698fdd71c7328fd 120 Hamap MF_00755 Ribonuclease P protein component 2 [rnp2]. 5 116 27.138 T 23-10-2018 IPR002759 Ribonuclease P/MRP protein subunit GO:0004540|GO:0008033 Reactome: R-HSA-6784531 A3L08_04975 9b111e8008664e62b2c3681629bde1ff 233 PIRSF PIRSF016933 4 223 6.6E-34 T 23-10-2018 IPR023596 Peptidase PrsW, archaeal/bacterial GO:0008233 A3L08_04975 9b111e8008664e62b2c3681629bde1ff 233 Pfam PF13367 Protease prsW family 31 201 3.0E-31 T 23-10-2018 IPR026898 Protease PrsW GO:0008233 A3L08_06275 a1065bcba1923f29dd79b0017b2222d2 187 Pfam PF01944 Stage II sporulation protein M 15 182 2.1E-31 T 23-10-2018 IPR002798 Stage II sporulation protein M-like A3L08_04120 477dfc87d5d342a8d34c3b24e6349048 56 Hamap MF_01364_A 30S ribosomal protein S14 type Z [rpsZ]. 2 56 17.392 T 23-10-2018 IPR023676 Ribosomal protein S14, type Z, archaeal GO:0003723|GO:0003735|GO:0006412|GO:0015935 A3L08_04120 477dfc87d5d342a8d34c3b24e6349048 56 Pfam PF00253 Ribosomal protein S14p/S29e 8 55 9.8E-10 T 23-10-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A3L08_04120 477dfc87d5d342a8d34c3b24e6349048 56 Gene3D G3DSA:4.10.830.10 1 56 2.5E-20 T 23-10-2018 A3L08_04120 477dfc87d5d342a8d34c3b24e6349048 56 ProSitePatterns PS00527 Ribosomal protein S14 signature. 23 44 - T 23-10-2018 IPR018271 Ribosomal protein S14, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_05480 be994ea628500bf4f72e6405bf369565 268 Pfam PF00753 Metallo-beta-lactamase superfamily 20 134 3.6E-17 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L08_05480 be994ea628500bf4f72e6405bf369565 268 Gene3D G3DSA:3.60.15.10 1 268 1.5E-73 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L08_05480 be994ea628500bf4f72e6405bf369565 268 SUPERFAMILY SSF56281 9 268 6.42E-36 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L08_05480 be994ea628500bf4f72e6405bf369565 268 SMART SM00849 21 188 4.5E-8 T 23-10-2018 IPR001279 Metallo-beta-lactamase A3L08_04700 9e5dee4b4931cee20ac7ca4bc5b83dac 224 Gene3D G3DSA:3.90.320.10 7 216 1.1E-23 T 23-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal A3L08_04700 9e5dee4b4931cee20ac7ca4bc5b83dac 224 Pfam PF08696 DNA replication factor Dna2 29 72 7.8E-5 T 23-10-2018 IPR014808 DNA replication factor Dna2, N-terminal Reactome: R-HSA-174437|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69166|Reactome: R-HSA-69473 A3L08_06555 110dd6834c61d6a421f98e81c9589416 80 Pfam PF13244 Domain of unknown function (DUF4040) 11 75 8.6E-12 T 23-10-2018 IPR025383 Domain of unknown function DUF4040 A3L08_05390 44a35821951de23dae3e2ced6ed96cae 388 Pfam PF04981 NMD3 family 6 276 7.4E-62 T 23-10-2018 IPR007064 Nmd3, N-terminal A3L08_05390 44a35821951de23dae3e2ced6ed96cae 388 SUPERFAMILY SSF50249 332 383 5.57E-6 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L08_05390 44a35821951de23dae3e2ced6ed96cae 388 Gene3D G3DSA:2.40.50.140 332 384 4.2E-9 T 23-10-2018 A3L08_06640 fee545850b5ea92119802aabd927c7b4 69 Gene3D G3DSA:2.30.30.240 2 69 2.9E-7 T 23-10-2018 A3L08_06640 fee545850b5ea92119802aabd927c7b4 69 Pfam PF05239 PRC-barrel domain 2 68 1.8E-12 T 23-10-2018 IPR027275 PRC-barrel domain A3L08_06640 fee545850b5ea92119802aabd927c7b4 69 SUPERFAMILY SSF50346 1 66 2.51E-14 T 23-10-2018 IPR011033 PRC-barrel-like superfamily A3L08_05550 f86df791cbc2db07e6ca5f2c3b611faa 133 Hamap MF_01490 Holliday junction resolvase Hjc [hjc]. 2 125 36.405 T 23-10-2018 IPR014428 Holliday junction resolvase Hjc, archaeal A3L08_05550 f86df791cbc2db07e6ca5f2c3b611faa 133 Gene3D G3DSA:3.40.1350.10 1 127 1.2E-37 T 23-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 A3L08_05550 f86df791cbc2db07e6ca5f2c3b611faa 133 PIRSF PIRSF004985 1 126 2.2E-38 T 23-10-2018 IPR014428 Holliday junction resolvase Hjc, archaeal A3L08_05550 f86df791cbc2db07e6ca5f2c3b611faa 133 ProDom PD015874 RESOLVASE HOLLIDAY JUNCTION ARCHAEAL HOLLIDAY-JUNCTION TYPE MJ0497 ORF-C21_024 PF1503 NEQ424 10 96 6.0E-28 T 23-10-2018 IPR014428 Holliday junction resolvase Hjc, archaeal A3L08_05550 f86df791cbc2db07e6ca5f2c3b611faa 133 Pfam PF01870 Archaeal holliday junction resolvase (hjc) 9 94 8.0E-30 T 23-10-2018 IPR002732 Holliday junction resolvase Hjc A3L08_05550 f86df791cbc2db07e6ca5f2c3b611faa 133 SUPERFAMILY SSF52980 3 109 6.03E-28 T 23-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 A3L08_02105 c2b9e601763fed26d505df25104ff85e 101 Gene3D G3DSA:3.30.70.1340 1 86 3.4E-35 T 23-10-2018 IPR023129 MTH889-like domain superfamily A3L08_02105 c2b9e601763fed26d505df25104ff85e 101 SUPERFAMILY SSF160363 4 93 1.57E-34 T 23-10-2018 IPR023129 MTH889-like domain superfamily A3L08_02105 c2b9e601763fed26d505df25104ff85e 101 Pfam PF02680 Uncharacterized ArCR, COG1888 5 90 5.6E-38 T 23-10-2018 IPR003831 Protein of unknown function DUF211 A3L08_02105 c2b9e601763fed26d505df25104ff85e 101 ProDom PD012512 ARCHAEA PH1931 STS176 TA1183 MJ0319 PRECURSOR TVG0378908 UNCHARACTERIZED DUF211 AF1549 12 95 2.0E-39 T 23-10-2018 IPR003831 Protein of unknown function DUF211 A3L08_06280 915273ee85939287a9da79d8581efdc9 92 Pfam PF10437 Bacterial lipoate protein ligase C-terminus 7 57 9.7E-8 T 23-10-2018 IPR019491 Lipoate protein ligase, C-terminal KEGG: 00785+6.3.1.20 A3L08_06280 915273ee85939287a9da79d8581efdc9 92 Gene3D G3DSA:3.30.390.50 1 88 2.0E-24 T 23-10-2018 A3L08_06280 915273ee85939287a9da79d8581efdc9 92 SUPERFAMILY SSF82649 7 86 1.36E-10 T 23-10-2018 A3L08_00975 652ae1a1ba4b3eda6f678f0af0d37891 505 Gene3D G3DSA:3.40.50.300 5 158 1.3E-37 T 23-10-2018 A3L08_00975 652ae1a1ba4b3eda6f678f0af0d37891 505 Gene3D G3DSA:1.10.8.60 161 220 1.0E-10 T 23-10-2018 A3L08_00975 652ae1a1ba4b3eda6f678f0af0d37891 505 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 47 154 3.9E-15 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A3L08_00975 652ae1a1ba4b3eda6f678f0af0d37891 505 SMART SM00382 43 160 2.8E-12 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L08_00975 652ae1a1ba4b3eda6f678f0af0d37891 505 SUPERFAMILY SSF52540 5 207 1.21E-44 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_00975 652ae1a1ba4b3eda6f678f0af0d37891 505 Hamap MF_01508 Replication factor C large subunit [rfcL]. 5 438 34.554 T 23-10-2018 IPR023935 Replication factor C, large subunit A3L08_08510 79116108187c9ca4a15d21ede7e97452 203 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 13 107 2.1E-22 T 23-10-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis A3L08_08510 79116108187c9ca4a15d21ede7e97452 203 Gene3D G3DSA:3.30.420.130 1 118 9.1E-28 T 23-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily A3L08_08510 79116108187c9ca4a15d21ede7e97452 203 SUPERFAMILY SSF53146 1 118 3.66E-28 T 23-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily A3L08_00305 87da292dc6011edfa31fdb90b4f1ae2d 81 Gene3D G3DSA:3.30.70.920 2 74 8.7E-21 T 23-10-2018 A3L08_00305 87da292dc6011edfa31fdb90b4f1ae2d 81 Pfam PF01037 Lrp/AsnC ligand binding domain 6 76 1.9E-15 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A3L08_00305 87da292dc6011edfa31fdb90b4f1ae2d 81 SUPERFAMILY SSF54909 2 76 2.82E-16 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel A3L08_01155 47a0e5936d900edb01f42b8791d6e06b 195 Pfam PF14470 Bacterial PH domain 17 109 5.5E-22 T 23-10-2018 IPR039519 YokE-like, PH domain A3L08_01155 47a0e5936d900edb01f42b8791d6e06b 195 Pfam PF09851 Short C-terminal domain 165 192 1.2E-11 T 23-10-2018 IPR018649 SHOCT domain A3L08_04730 cc413aba08d32fa2cbfb234231c51891 307 SUPERFAMILY SSF53795 105 191 6.41E-6 T 23-10-2018 A3L08_02240 bfb0258d6f1f3514985beeea57ea33a2 116 SMART SM01022 6 109 1.9E-14 T 23-10-2018 IPR007374 ASCH domain A3L08_02240 bfb0258d6f1f3514985beeea57ea33a2 116 SUPERFAMILY SSF88697 1 108 4.64E-37 T 23-10-2018 IPR015947 PUA-like superfamily A3L08_02240 bfb0258d6f1f3514985beeea57ea33a2 116 PIRSF PIRSF016134 2 111 2.8E-46 T 23-10-2018 IPR016645 Uncharacterised conserved protein UCP016134 A3L08_02240 bfb0258d6f1f3514985beeea57ea33a2 116 Pfam PF04266 ASCH domain 6 108 3.5E-17 T 23-10-2018 IPR007374 ASCH domain A3L08_02240 bfb0258d6f1f3514985beeea57ea33a2 116 Gene3D G3DSA:2.30.130.30 2 109 3.8E-43 T 23-10-2018 A3L08_00475 347855c1137d1fea8c58fee91cc2b9fb 544 Pfam PF09823 Domain of unknown function (DUF2357) 68 331 3.2E-31 T 23-10-2018 IPR018633 Domain of unknown function DUF2357 A3L08_00475 347855c1137d1fea8c58fee91cc2b9fb 544 Pfam PF04411 PD-(D/E)XK nuclease superfamily 355 504 2.3E-13 T 23-10-2018 IPR007505 PD-(D/E)XK nuclease superfamily 7 A3L08_07695 6c4746c8cf6a6625e6f7fff3ce238d60 278 SUPERFAMILY SSF101576 103 171 5.89E-5 T 23-10-2018 IPR036598 GOLD domain superfamily A3L08_07515 9c3d4311b711e3614f9c3f0d9f6ff2b2 222 SUPERFAMILY SSF53448 5 220 1.07E-52 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L08_07515 9c3d4311b711e3614f9c3f0d9f6ff2b2 222 Gene3D G3DSA:3.90.550.10 2 221 1.9E-61 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L08_07515 9c3d4311b711e3614f9c3f0d9f6ff2b2 222 Pfam PF00535 Glycosyl transferase family 2 8 167 1.2E-36 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A3L08_07210 bf7e9180cdbb8a7b6f7450bf2456d506 220 SUPERFAMILY SSF56784 4 186 9.72E-14 T 23-10-2018 IPR036412 HAD-like superfamily A3L08_07210 bf7e9180cdbb8a7b6f7450bf2456d506 220 Gene3D G3DSA:1.10.150.520 15 84 1.4E-8 T 23-10-2018 A3L08_07210 bf7e9180cdbb8a7b6f7450bf2456d506 220 Gene3D G3DSA:3.40.50.1000 5 134 1.4E-8 T 23-10-2018 IPR023214 HAD superfamily A3L08_09430 6270cb006f0b307a2dd70887f0f02b74 102 SUPERFAMILY SSF50346 4 79 1.46E-12 T 23-10-2018 IPR011033 PRC-barrel-like superfamily A3L08_09430 6270cb006f0b307a2dd70887f0f02b74 102 Gene3D G3DSA:2.30.30.240 4 81 6.3E-6 T 23-10-2018 A3L08_09430 6270cb006f0b307a2dd70887f0f02b74 102 Pfam PF05239 PRC-barrel domain 3 82 6.2E-14 T 23-10-2018 IPR027275 PRC-barrel domain A3L08_01020 9b46337c911afb860760ceb8f02e073c 383 Gene3D G3DSA:3.40.50.1100 91 186 3.4E-107 T 23-10-2018 A3L08_01020 9b46337c911afb860760ceb8f02e073c 383 SUPERFAMILY SSF53686 3 360 2.1E-88 T 23-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme A3L08_01020 9b46337c911afb860760ceb8f02e073c 383 Gene3D G3DSA:3.40.50.1100 43 358 3.4E-107 T 23-10-2018 A3L08_01020 9b46337c911afb860760ceb8f02e073c 383 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 57 353 1.2E-69 T 23-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme A3L08_01020 9b46337c911afb860760ceb8f02e073c 383 TIGRFAM TIGR00260 thrC: threonine synthase 54 358 3.7E-59 T 23-10-2018 IPR004450 Threonine synthase-like A3L08_07190 681fe0a4a0fcd249d4928456a529f55b 456 TIGRFAM TIGR00797 matE: MATE efflux family protein 17 419 9.6E-127 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A3L08_07190 681fe0a4a0fcd249d4928456a529f55b 456 PIRSF PIRSF006603 5 456 4.2E-110 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A3L08_07190 681fe0a4a0fcd249d4928456a529f55b 456 Pfam PF01554 MatE 241 407 1.0E-35 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A3L08_07190 681fe0a4a0fcd249d4928456a529f55b 456 Pfam PF01554 MatE 17 177 2.6E-41 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A3L08_04820 404968c25c9085db08e9b5571a67a425 216 Gene3D G3DSA:3.40.50.790 59 150 6.0E-77 T 23-10-2018 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich A3L08_04820 404968c25c9085db08e9b5571a67a425 216 Pfam PF00687 Ribosomal protein L1p/L10e family 21 210 2.1E-48 T 23-10-2018 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein A3L08_04820 404968c25c9085db08e9b5571a67a425 216 SUPERFAMILY SSF56808 5 214 2.49E-65 T 23-10-2018 IPR023674 Ribosomal protein L1-like A3L08_04820 404968c25c9085db08e9b5571a67a425 216 Gene3D G3DSA:3.30.190.20 13 213 6.0E-77 T 23-10-2018 A3L08_04820 404968c25c9085db08e9b5571a67a425 216 Hamap MF_01318_A 50S ribosomal protein L1 [rplA]. 4 215 37.181 T 23-10-2018 IPR023669 Ribosomal protein L1, archaea GO:0003723|GO:0003735|GO:0006412|GO:0015934 A3L08_04820 404968c25c9085db08e9b5571a67a425 216 ProSitePatterns PS01199 Ribosomal protein L1 signature. 114 133 - T 23-10-2018 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_04820 404968c25c9085db08e9b5571a67a425 216 PIRSF PIRSF002155 1 216 1.5E-66 T 23-10-2018 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A3L08_03695 3592d428a534e0038f81f0bf693414d5 100 TIGRFAM TIGR00106 TIGR00106: uncharacterized protein, MTH1187 family 2 97 3.6E-30 T 23-10-2018 IPR002767 Thiamine-binding protein A3L08_03695 3592d428a534e0038f81f0bf693414d5 100 Gene3D G3DSA:3.30.70.930 1 97 2.3E-36 T 23-10-2018 IPR029756 MTH1187/YkoF-like A3L08_03695 3592d428a534e0038f81f0bf693414d5 100 Pfam PF01910 Thiamine-binding protein 4 93 2.5E-33 T 23-10-2018 IPR002767 Thiamine-binding protein A3L08_03695 3592d428a534e0038f81f0bf693414d5 100 SUPERFAMILY SSF89957 2 96 1.09E-30 T 23-10-2018 IPR029756 MTH1187/YkoF-like A3L08_00390 6273f50682e890734817bde7cf594766 133 Pfam PF04039 Domain related to MnhB subunit of Na+/H+ antiporter 6 120 1.0E-24 T 23-10-2018 IPR007182 Na+/H+ antiporter MnhB subunit-related protein A3L08_00735 67d62bf090ec907884bf586a3440219e 63 SUPERFAMILY SSF54862 3 61 2.86E-15 T 23-10-2018 A3L08_00735 67d62bf090ec907884bf586a3440219e 63 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 7 59 2.1E-17 T 23-10-2018 A3L08_00735 67d62bf090ec907884bf586a3440219e 63 PRINTS PR00352 3Fe-4S ferredoxin signature 7 18 5.2E-10 T 23-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 A3L08_00735 67d62bf090ec907884bf586a3440219e 63 PRINTS PR00352 3Fe-4S ferredoxin signature 18 28 5.2E-10 T 23-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 A3L08_00735 67d62bf090ec907884bf586a3440219e 63 PRINTS PR00352 3Fe-4S ferredoxin signature 46 58 5.2E-10 T 23-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 A3L08_00735 67d62bf090ec907884bf586a3440219e 63 Gene3D G3DSA:3.30.70.20 3 62 3.9E-23 T 23-10-2018 A3L08_06240 b05a9e5e3f97bbf8dae7481380ed09ea 419 Gene3D G3DSA:3.20.20.70 112 356 1.4E-38 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L08_06240 b05a9e5e3f97bbf8dae7481380ed09ea 419 SUPERFAMILY SSF102114 109 339 2.09E-39 T 23-10-2018 A3L08_06240 b05a9e5e3f97bbf8dae7481380ed09ea 419 SMART SM00729 115 333 8.6E-15 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A3L08_06240 b05a9e5e3f97bbf8dae7481380ed09ea 419 Pfam PF04055 Radical SAM superfamily 123 287 4.2E-27 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L08_08535 a17d43c2953b8cf99b97779aa598fddc 102 SUPERFAMILY SSF54909 2 69 2.55E-6 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel A3L08_03550 77fec6e6534c45dc96db515eeb99da16 391 SUPERFAMILY SSF69322 68 380 3.92E-10 T 23-10-2018 A3L08_00330 749d760dc4eb71e8be55ce3a179343df 291 SUPERFAMILY SSF63380 2 94 1.16E-17 T 23-10-2018 IPR017938 Riboflavin synthase-like beta-barrel A3L08_00330 749d760dc4eb71e8be55ce3a179343df 291 Gene3D G3DSA:3.40.50.80 101 212 1.9E-18 T 23-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A3L08_00330 749d760dc4eb71e8be55ce3a179343df 291 Gene3D G3DSA:2.40.30.10 1 93 7.1E-17 T 23-10-2018 A3L08_00330 749d760dc4eb71e8be55ce3a179343df 291 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 222 258 3.8E-10 T 23-10-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain A3L08_00330 749d760dc4eb71e8be55ce3a179343df 291 SUPERFAMILY SSF52343 90 257 6.69E-13 T 23-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A3L08_00330 749d760dc4eb71e8be55ce3a179343df 291 PIRSF PIRSF006816 1 264 4.7E-57 T 23-10-2018 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 A3L08_02640 20068c77f42eeee991c5c46fb4d74e81 302 SMART SM00729 56 253 1.3E-6 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A3L08_02640 20068c77f42eeee991c5c46fb4d74e81 302 Pfam PF04055 Radical SAM superfamily 102 210 5.5E-13 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A3L08_02640 20068c77f42eeee991c5c46fb4d74e81 302 SUPERFAMILY SSF102114 60 259 2.09E-31 T 23-10-2018 A3L08_02640 20068c77f42eeee991c5c46fb4d74e81 302 Gene3D G3DSA:3.20.20.70 51 281 1.1E-30 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A3L08_00965 640fda1301d4fb867b123b2f32e7db99 176 Pfam PF05763 Protein of unknown function (DUF835) 1 113 1.5E-30 T 23-10-2018 IPR008553 Domain of unknown function DUF835 A3L08_03800 247bcaacd19315630e8d97cedd2fa1f0 348 Pfam PF01594 AI-2E family transporter 11 322 5.5E-36 T 23-10-2018 IPR002549 Transmembrane protein TqsA-like A3L08_08760 0d00be7abc6e6a7eff186d2f7ccc4d6b 416 SMART SM00933 45 381 4.2E-15 T 23-10-2018 IPR018977 NurA domain A3L08_08760 0d00be7abc6e6a7eff186d2f7ccc4d6b 416 Pfam PF09376 NurA domain 46 381 2.5E-31 T 23-10-2018 IPR018977 NurA domain A3L08_04155 f61d83936132e519ae1758305c265ce3 155 Gene3D G3DSA:3.30.1390.20 5 143 2.1E-55 T 23-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily A3L08_04155 f61d83936132e519ae1758305c265ce3 155 SUPERFAMILY SSF55129 5 155 3.14E-49 T 23-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily A3L08_04155 f61d83936132e519ae1758305c265ce3 155 TIGRFAM TIGR01309 uL30_arch: ribosomal protein uL30 4 155 3.9E-63 T 23-10-2018 IPR005997 Ribosomal protein L30, archaeal GO:0003735|GO:0006412|GO:0015934 A3L08_04155 f61d83936132e519ae1758305c265ce3 155 Pfam PF00327 Ribosomal protein L30p/L7e 6 54 2.2E-15 T 23-10-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain A3L08_04155 f61d83936132e519ae1758305c265ce3 155 Hamap MF_01371_A 50S ribosomal protein L30 [rpmD]. 1 155 81.722 T 23-10-2018 IPR005997 Ribosomal protein L30, archaeal GO:0003735|GO:0006412|GO:0015934 A3L08_04155 f61d83936132e519ae1758305c265ce3 155 Gene3D G3DSA:1.10.15.30 60 114 2.1E-55 T 23-10-2018 IPR023106 Ribosomal protein L30, central domain, archaeal type A3L08_04155 f61d83936132e519ae1758305c265ce3 155 ProSitePatterns PS00634 Ribosomal protein L30 signature. 22 54 - T 23-10-2018 IPR018038 Ribosomal protein L30, conserved site A3L08_06120 5b0a0b79f511202865c3c47376732c14 154 Gene3D G3DSA:1.25.40.10 2 58 9.3E-8 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A3L08_06120 5b0a0b79f511202865c3c47376732c14 154 Gene3D G3DSA:1.25.40.10 59 153 3.1E-19 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A3L08_06120 5b0a0b79f511202865c3c47376732c14 154 SUPERFAMILY SSF48452 34 134 1.95E-5 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A3L08_09785 270a1ee2c106e69871c236fc8d3721b7 248 Gene3D G3DSA:1.10.3720.10 5 248 2.6E-65 T 23-10-2018 IPR035906 MetI-like superfamily A3L08_09785 270a1ee2c106e69871c236fc8d3721b7 248 SUPERFAMILY SSF161098 6 241 3.92E-48 T 23-10-2018 IPR035906 MetI-like superfamily A3L08_09785 270a1ee2c106e69871c236fc8d3721b7 248 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 70 242 1.6E-22 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A3L08_05620 3677d936634ffca8462a5092d019f83d 336 Pfam PF01594 AI-2E family transporter 10 322 4.8E-37 T 23-10-2018 IPR002549 Transmembrane protein TqsA-like A3L08_06190 58670c911560e5bbdbafc341fe79364a 309 Pfam PF00146 NADH dehydrogenase 8 306 1.1E-50 T 23-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L08_02760 ae836a9db281af2d9eb2e680e58eab6f 247 Pfam PF13649 Methyltransferase domain 85 158 1.6E-7 T 23-10-2018 A3L08_02760 ae836a9db281af2d9eb2e680e58eab6f 247 Gene3D G3DSA:3.40.50.150 66 247 8.0E-42 T 23-10-2018 A3L08_02760 ae836a9db281af2d9eb2e680e58eab6f 247 SUPERFAMILY SSF53335 9 232 2.84E-25 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L08_06335 c39c79788a79c91d85e95b8d0c5d5c95 66 Pfam PF04021 Class III signal peptide 5 29 2.2E-6 T 23-10-2018 IPR007166 Class III signal peptide motif A3L08_08905 74576f48a9bf62110f2ec82ba04653ac 153 Pfam PF09123 Domain of unknown function (DUF1931) 11 150 4.1E-47 T 23-10-2018 IPR015207 Protein of unknown function DUF1931 A3L08_08905 74576f48a9bf62110f2ec82ba04653ac 153 Gene3D G3DSA:1.10.20.10 5 153 7.0E-38 T 23-10-2018 IPR009072 Histone-fold GO:0046982 A3L08_08905 74576f48a9bf62110f2ec82ba04653ac 153 SUPERFAMILY SSF47113 1 153 4.19E-53 T 23-10-2018 IPR009072 Histone-fold GO:0046982 A3L08_05470 8d2bb42fcef2d7da8a2599d1828c88a8 301 Pfam PF12773 Double zinc ribbon 257 300 5.9E-9 T 23-10-2018 IPR025874 Double zinc ribbon A3L08_06225 a17366839fabd144240f69a7fa27b67d 84 Pfam PF04066 Multiple resistance and pH regulation protein F (MrpF / PhaF) 30 81 1.7E-18 T 23-10-2018 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 A3L08_06595 7b8d5045513ebcba14a875997da724f2 405 Pfam PF00465 Iron-containing alcohol dehydrogenase 30 376 3.3E-97 T 23-10-2018 IPR001670 Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 A3L08_06595 7b8d5045513ebcba14a875997da724f2 405 Gene3D G3DSA:1.20.1090.10 200 399 5.3E-47 T 23-10-2018 A3L08_06595 7b8d5045513ebcba14a875997da724f2 405 SUPERFAMILY SSF56796 13 399 3.53E-106 T 23-10-2018 A3L08_06595 7b8d5045513ebcba14a875997da724f2 405 Gene3D G3DSA:3.40.50.1970 11 196 5.3E-49 T 23-10-2018 A3L08_04430 2ba4c4bb3581ff5bd775267179c649f0 439 Gene3D G3DSA:3.40.630.10 1 210 5.8E-51 T 23-10-2018 A3L08_04430 2ba4c4bb3581ff5bd775267179c649f0 439 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 66 75 - T 23-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 A3L08_04430 2ba4c4bb3581ff5bd775267179c649f0 439 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 101 138 - T 23-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 A3L08_04430 2ba4c4bb3581ff5bd775267179c649f0 439 Pfam PF01546 Peptidase family M20/M25/M40 67 433 1.7E-33 T 23-10-2018 IPR002933 Peptidase M20 GO:0016787 A3L08_04430 2ba4c4bb3581ff5bd775267179c649f0 439 SUPERFAMILY SSF53187 3 437 1.23E-58 T 23-10-2018 A3L08_04430 2ba4c4bb3581ff5bd775267179c649f0 439 Gene3D G3DSA:3.30.70.360 313 352 2.1E-14 T 23-10-2018 A3L08_04430 2ba4c4bb3581ff5bd775267179c649f0 439 Gene3D G3DSA:3.40.630.10 353 427 2.1E-14 T 23-10-2018 A3L08_08600 41a1b5b2df1353b89ae91c15b8f09374 129 Gene3D G3DSA:3.40.630.30 1 118 2.1E-23 T 23-10-2018 A3L08_08600 41a1b5b2df1353b89ae91c15b8f09374 129 Pfam PF00583 Acetyltransferase (GNAT) family 13 118 7.9E-11 T 23-10-2018 IPR000182 GNAT domain A3L08_08600 41a1b5b2df1353b89ae91c15b8f09374 129 SUPERFAMILY SSF55729 18 125 1.36E-15 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase A3L08_04935 9d425ca3e5a300ad0a4c4d3d1794e7a7 250 SUPERFAMILY SSF51695 8 216 1.07E-58 T 23-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 A3L08_04935 9d425ca3e5a300ad0a4c4d3d1794e7a7 250 Gene3D G3DSA:3.20.20.190 3 250 5.0E-95 T 23-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 A3L08_04935 9d425ca3e5a300ad0a4c4d3d1794e7a7 250 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 14 214 2.4E-31 T 23-10-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 A3L08_05880 9ef0e86b97b23e1d067f225d148db6a6 164 Pfam PF01230 HIT domain 33 125 1.7E-14 T 23-10-2018 IPR001310 Histidine triad (HIT) protein A3L08_05880 9ef0e86b97b23e1d067f225d148db6a6 164 Gene3D G3DSA:3.30.428.10 1 163 6.1E-60 T 23-10-2018 IPR036265 HIT-like superfamily A3L08_05880 9ef0e86b97b23e1d067f225d148db6a6 164 SUPERFAMILY SSF54197 1 160 1.29E-47 T 23-10-2018 IPR036265 HIT-like superfamily A3L08_00070 58e4fcf91303dbc77d32f16cf6a3b536 198 SUPERFAMILY SSF46785 6 173 2.51E-28 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L08_00070 58e4fcf91303dbc77d32f16cf6a3b536 198 Pfam PF01022 Bacterial regulatory protein, arsR family 16 61 5.4E-13 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L08_00070 58e4fcf91303dbc77d32f16cf6a3b536 198 SMART SM00418 9 89 2.9E-17 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A3L08_00070 58e4fcf91303dbc77d32f16cf6a3b536 198 Gene3D G3DSA:1.10.10.10 4 105 1.4E-27 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L08_03620 86fb052c470091c0498aefee9672ef5a 125 SUPERFAMILY SSF50249 24 89 1.77E-6 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A3L08_05190 3c358ce34b60f516db24876fc717e52b 189 PIRSF PIRSF019325 1 189 3.5E-74 T 23-10-2018 IPR016758 Glucose-6-phosphate isomerase, archaea/bacteria GO:0004347|GO:0005506 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385 A3L08_05190 3c358ce34b60f516db24876fc717e52b 189 Gene3D G3DSA:2.60.120.10 1 189 1.1E-73 T 23-10-2018 IPR014710 RmlC-like jelly roll fold A3L08_05190 3c358ce34b60f516db24876fc717e52b 189 Pfam PF06560 Glucose-6-phosphate isomerase (GPI) 25 182 3.9E-40 T 23-10-2018 IPR010551 Glucose-6-phosphate isomerase, prokaryote GO:0004347|GO:0005737|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385 A3L08_05190 3c358ce34b60f516db24876fc717e52b 189 SUPERFAMILY SSF51182 2 188 4.98E-44 T 23-10-2018 IPR011051 RmlC-like cupin domain superfamily A3L08_09710 69fb7db07bd5c996a59f506ee5b5647e 187 Gene3D G3DSA:1.20.120.1760 7 187 6.9E-50 T 23-10-2018 A3L08_09710 69fb7db07bd5c996a59f506ee5b5647e 187 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 68 90 - T 23-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 A3L08_09710 69fb7db07bd5c996a59f506ee5b5647e 187 Pfam PF01066 CDP-alcohol phosphatidyltransferase 26 90 2.7E-16 T 23-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 A3L08_04375 1e257ffc7407d1ae3b4b2fae6e482b22 354 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 78 345 5.8E-63 T 23-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme A3L08_04375 1e257ffc7407d1ae3b4b2fae6e482b22 354 Gene3D G3DSA:3.40.50.1100 91 186 8.7E-83 T 23-10-2018 A3L08_04375 1e257ffc7407d1ae3b4b2fae6e482b22 354 Gene3D G3DSA:3.40.50.1100 62 349 8.7E-83 T 23-10-2018 A3L08_04375 1e257ffc7407d1ae3b4b2fae6e482b22 354 SUPERFAMILY SSF53686 2 352 2.36E-71 T 23-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme A3L08_05310 97aeecd5137c263403818117f1a8d109 106 Pfam PF01909 Nucleotidyltransferase domain 10 100 2.3E-12 T 23-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 A3L08_05310 97aeecd5137c263403818117f1a8d109 106 Gene3D G3DSA:3.30.460.10 1 103 2.2E-20 T 23-10-2018 A3L08_05310 97aeecd5137c263403818117f1a8d109 106 SUPERFAMILY SSF81301 3 103 6.54E-16 T 23-10-2018 A3L08_09700 da28e06d1785a7d5927b6cd3f3d093e4 535 Gene3D G3DSA:3.10.620.30 263 401 2.9E-6 T 23-10-2018 A3L08_09700 da28e06d1785a7d5927b6cd3f3d093e4 535 Pfam PF01841 Transglutaminase-like superfamily 298 387 3.5E-7 T 23-10-2018 IPR002931 Transglutaminase-like A3L08_09700 da28e06d1785a7d5927b6cd3f3d093e4 535 SUPERFAMILY SSF54001 288 442 4.35E-9 T 23-10-2018 IPR038765 Papain-like cysteine peptidase superfamily A3L08_00605 e83a9aa33ad2ad03236a2f8d386137cb 166 Pfam PF01965 DJ-1/PfpI family 1 163 1.5E-61 T 23-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 A3L08_00605 e83a9aa33ad2ad03236a2f8d386137cb 166 Gene3D G3DSA:3.40.50.880 1 166 4.9E-54 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A3L08_00605 e83a9aa33ad2ad03236a2f8d386137cb 166 SUPERFAMILY SSF52317 1 165 2.36E-53 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A3L08_00605 e83a9aa33ad2ad03236a2f8d386137cb 166 TIGRFAM TIGR01382 PfpI: intracellular protease, PfpI family 2 165 2.1E-69 T 23-10-2018 IPR006286 Deglycase PfpI A3L08_00455 5f2ea019dc7dc861458dd3cca9410bd8 488 Pfam PF00474 Sodium:solute symporter family 36 430 8.1E-64 T 23-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 A3L08_00455 5f2ea019dc7dc861458dd3cca9410bd8 488 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 35 431 1.1E-62 T 23-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 A3L08_00455 5f2ea019dc7dc861458dd3cca9410bd8 488 Gene3D G3DSA:1.20.1730.10 24 488 1.2E-76 T 23-10-2018 IPR038377 Sodium/glucose symporter superfamily A3L08_06825 20d2b20eee3936c012bf8b9c7c7d4996 410 SUPERFAMILY SSF53822 49 287 3.83E-9 T 23-10-2018 IPR028082 Periplasmic binding protein-like I A3L08_06825 20d2b20eee3936c012bf8b9c7c7d4996 410 Pfam PF02608 ABC transporter substrate-binding protein PnrA-like 37 339 2.3E-53 T 23-10-2018 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 A3L08_06825 20d2b20eee3936c012bf8b9c7c7d4996 410 Gene3D G3DSA:3.40.50.2300 138 324 1.2E-87 T 23-10-2018 A3L08_06825 20d2b20eee3936c012bf8b9c7c7d4996 410 Gene3D G3DSA:3.40.50.2300 36 312 1.2E-87 T 23-10-2018 A3L08_09530 0c58d26d93676980a17fcaa24f2d0c48 285 SUPERFAMILY SSF56281 16 278 2.39E-42 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L08_09530 0c58d26d93676980a17fcaa24f2d0c48 285 Gene3D G3DSA:3.60.15.10 50 127 1.8E-24 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A3L08_09530 0c58d26d93676980a17fcaa24f2d0c48 285 Gene3D G3DSA:3.40.50.10890 128 169 1.8E-24 T 23-10-2018 A3L08_04620 1ee4bcd0e6d27d3858fb24e240658e4e 251 Gene3D G3DSA:3.40.50.1440 117 249 2.1E-7 T 23-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 A3L08_04620 1ee4bcd0e6d27d3858fb24e240658e4e 251 SUPERFAMILY SSF55307 159 244 4.58E-12 T 23-10-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 A3L08_02580 cbe4f2e5a3d7bd19aa5c21fa09e13ace 162 Pfam PF00137 ATP synthase subunit C 97 155 2.0E-14 T 23-10-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 A3L08_02580 cbe4f2e5a3d7bd19aa5c21fa09e13ace 162 Pfam PF00137 ATP synthase subunit C 9 68 2.4E-12 T 23-10-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 A3L08_02580 cbe4f2e5a3d7bd19aa5c21fa09e13ace 162 SUPERFAMILY SSF81333 6 70 4.05E-10 T 23-10-2018 IPR035921 F/V-ATP synthase subunit C superfamily A3L08_02580 cbe4f2e5a3d7bd19aa5c21fa09e13ace 162 Gene3D G3DSA:1.20.120.610 2 158 1.5E-38 T 23-10-2018 A3L08_02580 cbe4f2e5a3d7bd19aa5c21fa09e13ace 162 PRINTS PR00122 Vacuolar ATP synthase 16kDa subunit signature 27 51 2.1E-6 T 23-10-2018 IPR000245 V-ATPase proteolipid subunit GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A3L08_02580 cbe4f2e5a3d7bd19aa5c21fa09e13ace 162 PRINTS PR00122 Vacuolar ATP synthase 16kDa subunit signature 134 157 2.1E-6 T 23-10-2018 IPR000245 V-ATPase proteolipid subunit GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A3L08_02580 cbe4f2e5a3d7bd19aa5c21fa09e13ace 162 PRINTS PR00122 Vacuolar ATP synthase 16kDa subunit signature 107 133 2.1E-6 T 23-10-2018 IPR000245 V-ATPase proteolipid subunit GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A3L08_02580 cbe4f2e5a3d7bd19aa5c21fa09e13ace 162 SUPERFAMILY SSF81333 89 156 1.12E-12 T 23-10-2018 IPR035921 F/V-ATP synthase subunit C superfamily A3L08_07760 a1dfeb47a07f46242659fef2a571f517 114 Gene3D G3DSA:2.60.120.10 10 105 2.2E-21 T 23-10-2018 IPR014710 RmlC-like jelly roll fold A3L08_07760 a1dfeb47a07f46242659fef2a571f517 114 SUPERFAMILY SSF51182 10 101 1.32E-23 T 23-10-2018 IPR011051 RmlC-like cupin domain superfamily A3L08_07760 a1dfeb47a07f46242659fef2a571f517 114 Pfam PF07883 Cupin domain 32 100 3.2E-18 T 23-10-2018 IPR013096 Cupin 2, conserved barrel A3L08_06835 f34eb6ffc7ee3d3d24bd84d427a8dcae 350 Pfam PF02653 Branched-chain amino acid transport system / permease component 60 331 8.1E-36 T 23-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 A3L08_01370 32fe2f44738317dc34b57515b1d8d4ea 255 Pfam PF01061 ABC-2 type transporter 8 209 1.1E-13 T 23-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 A3L08_01370 32fe2f44738317dc34b57515b1d8d4ea 255 PIRSF PIRSF006648 1 244 7.4E-17 T 23-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A3L08_08315 0398c3d58c6793a6a1406a547b4bb74e 424 Pfam PF08532 Beta-galactosidase trimerisation domain 81 210 1.4E-10 T 23-10-2018 IPR013738 Beta-galactosidase trimerisation GO:0004565|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 A3L08_08315 0398c3d58c6793a6a1406a547b4bb74e 424 SUPERFAMILY SSF52317 53 206 2.14E-11 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A3L08_08315 0398c3d58c6793a6a1406a547b4bb74e 424 Gene3D G3DSA:3.40.50.880 39 206 4.4E-18 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A3L08_08870 36fbc45fa02a5ad8b54f14324d3c08c2 170 TIGRFAM TIGR00288 TIGR00288: TIGR00288 family protein 22 167 7.8E-62 T 23-10-2018 IPR002790 Conserved hypothetical protein CHP00288 A3L08_08870 36fbc45fa02a5ad8b54f14324d3c08c2 170 Gene3D G3DSA:3.40.50.1010 24 166 2.5E-9 T 23-10-2018 A3L08_08870 36fbc45fa02a5ad8b54f14324d3c08c2 170 Pfam PF01936 NYN domain 32 163 5.4E-19 T 23-10-2018 IPR021139 NYN domain, limkain-b1-type A3L08_08870 36fbc45fa02a5ad8b54f14324d3c08c2 170 ProDom PD010896 FAMILY DUF88 ARCHAEBACTERIAL PROTEIN MJ0482 PH0073 PF2040 VNG1608C MA3857 PF2039 33 105 8.0E-29 T 23-10-2018 A3L08_04205 a52d02b98f2ca8bd6bc57053d59203cf 195 SUPERFAMILY SSF53335 6 190 5.29E-40 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L08_04205 a52d02b98f2ca8bd6bc57053d59203cf 195 Gene3D G3DSA:3.40.50.150 5 193 4.5E-48 T 23-10-2018 A3L08_04205 a52d02b98f2ca8bd6bc57053d59203cf 195 Pfam PF05175 Methyltransferase small domain 28 191 3.5E-44 T 23-10-2018 IPR007848 Methyltransferase small domain GO:0008168 A3L08_02775 45e18f0876a3fc3405ad70bc7caa841a 111 Gene3D G3DSA:1.10.10.1150 39 104 1.1E-8 T 23-10-2018 A3L08_02775 45e18f0876a3fc3405ad70bc7caa841a 111 Pfam PF05402 Coenzyme PQQ synthesis protein D (PqqD) 27 102 4.0E-16 T 23-10-2018 IPR008792 Coenzyme PQQ synthesis D A3L08_07455 4eca926584ac8b7e520a58d8daeab1bc 290 Pfam PF13588 Type I restriction enzyme R protein N terminus (HSDR_N) 25 119 1.8E-9 T 23-10-2018 IPR029464 Type I restriction enzyme R protein, N-terminal domain A3L08_07455 4eca926584ac8b7e520a58d8daeab1bc 290 Gene3D G3DSA:3.90.1570.30 4 144 4.9E-6 T 23-10-2018 A3L08_09110 7bc480bee456fb4bd94117169ab43afb 334 Gene3D G3DSA:2.40.100.10 171 311 6.4E-50 T 23-10-2018 IPR029000 Cyclophilin-like domain superfamily A3L08_09110 7bc480bee456fb4bd94117169ab43afb 334 SMART SM00797 23 300 1.1E-136 T 23-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B A3L08_09110 7bc480bee456fb4bd94117169ab43afb 334 Pfam PF02626 Carboxyltransferase domain, subdomain A and B 24 283 2.1E-84 T 23-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B A3L08_09110 7bc480bee456fb4bd94117169ab43afb 334 TIGRFAM TIGR00724 urea_amlyse_rel: biotin-dependent carboxylase uncharacterized domain 2 307 7.7E-106 T 23-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B A3L08_09110 7bc480bee456fb4bd94117169ab43afb 334 SUPERFAMILY SSF50891 174 290 6.07E-13 T 23-10-2018 IPR029000 Cyclophilin-like domain superfamily A3L08_02850 8448d2dc4e2a0f9553657793851c39d0 254 Pfam PF05763 Protein of unknown function (DUF835) 124 241 1.8E-34 T 23-10-2018 IPR008553 Domain of unknown function DUF835 A3L08_02665 932b182b8848cf7dd47f77f08ab470ed 489 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 301 488 2.6E-28 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A3L08_02665 932b182b8848cf7dd47f77f08ab470ed 489 Gene3D G3DSA:1.10.3720.10 273 488 1.5E-22 T 23-10-2018 IPR035906 MetI-like superfamily A3L08_02665 932b182b8848cf7dd47f77f08ab470ed 489 SUPERFAMILY SSF161098 277 470 1.18E-23 T 23-10-2018 IPR035906 MetI-like superfamily A3L08_02665 932b182b8848cf7dd47f77f08ab470ed 489 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 11 67 5.1E-5 T 23-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain A3L08_00815 5339f79c30f032fdeca194b189cb0074 132 Pfam PF10066 Uncharacterized conserved protein (DUF2304) 4 108 1.9E-26 T 23-10-2018 IPR019277 Protein of unknown function DUF2304 A3L08_01820 305c67026baed68d3f36d8e3d04ae0df 161 SMART SM00981 63 150 2.2E-14 T 23-10-2018 IPR004114 THUMP domain GO:0003723 A3L08_01820 305c67026baed68d3f36d8e3d04ae0df 161 SUPERFAMILY SSF143437 57 148 6.28E-15 T 23-10-2018 A3L08_01820 305c67026baed68d3f36d8e3d04ae0df 161 Pfam PF02926 THUMP domain 26 149 8.9E-21 T 23-10-2018 IPR004114 THUMP domain GO:0003723 A3L08_01820 305c67026baed68d3f36d8e3d04ae0df 161 Gene3D G3DSA:3.30.2130.30 2 152 6.6E-13 T 23-10-2018 A3L08_06575 834e5f1c9d8369b5fff8ae7a3707a2b3 510 Pfam PF00361 Proton-conducting membrane transporter 130 432 2.7E-55 T 23-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L08_06575 834e5f1c9d8369b5fff8ae7a3707a2b3 510 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 246 270 3.8E-14 T 23-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L08_06575 834e5f1c9d8369b5fff8ae7a3707a2b3 510 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 390 416 3.8E-14 T 23-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L08_06575 834e5f1c9d8369b5fff8ae7a3707a2b3 510 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 338 357 3.8E-14 T 23-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L08_06575 834e5f1c9d8369b5fff8ae7a3707a2b3 510 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 165 189 3.8E-14 T 23-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L08_08720 e591e42c071231904922566235259cb9 81 Hamap MF_01245 UPF0248 protein . 10 79 18.723 T 23-10-2018 IPR007547 Uncharacterised protein family UPF0248 A3L08_08720 e591e42c071231904922566235259cb9 81 Pfam PF04457 Protein of unknown function (DUF504) 26 77 1.3E-14 T 23-10-2018 IPR007547 Uncharacterised protein family UPF0248 A3L08_00195 f755c35b189c82ec08b48c9ed8cb8e27 87 Pfam PF01169 Uncharacterized protein family UPF0016 6 79 2.5E-22 T 23-10-2018 IPR001727 Gdt1 family A3L08_01285 8c31d8c00ef69be182ace471eebab9ee 111 Pfam PF01849 NAC domain 6 62 4.3E-12 T 23-10-2018 IPR002715 Nascent polypeptide-associated complex NAC domain A3L08_01285 8c31d8c00ef69be182ace471eebab9ee 111 Hamap MF_00814 Nascent polypeptide-associated complex protein [nac]. 7 109 21.466 T 23-10-2018 IPR005231 Nascent polypeptide-associated complex (NAC), archaeal GO:0003723 A3L08_01285 8c31d8c00ef69be182ace471eebab9ee 111 SUPERFAMILY SSF46934 70 110 1.02E-8 T 23-10-2018 IPR009060 UBA-like superfamily GO:0005515 A3L08_01285 8c31d8c00ef69be182ace471eebab9ee 111 Gene3D G3DSA:2.20.70.30 10 68 4.7E-23 T 23-10-2018 IPR038187 NAC A/B domain superfamily A3L08_01285 8c31d8c00ef69be182ace471eebab9ee 111 TIGRFAM TIGR00264 TIGR00264: alpha-NAC homolog 3 110 1.4E-36 T 23-10-2018 IPR005231 Nascent polypeptide-associated complex (NAC), archaeal GO:0003723 A3L08_01285 8c31d8c00ef69be182ace471eebab9ee 111 Gene3D G3DSA:1.10.8.10 70 109 4.4E-20 T 23-10-2018 A3L08_01285 8c31d8c00ef69be182ace471eebab9ee 111 SMART SM01407 6 66 1.8E-17 T 23-10-2018 IPR002715 Nascent polypeptide-associated complex NAC domain A3L08_05915 2cc904b5d9a553826d313bd4574c6a94 138 TIGRFAM TIGR03161 ribazole_CobZ: alpha-ribazole phosphatase CobZ 8 134 3.2E-52 T 23-10-2018 IPR017577 Alpha-ribazole phosphatase, CobZ A3L08_05915 2cc904b5d9a553826d313bd4574c6a94 138 SUPERFAMILY SSF101307 6 134 1.24E-33 T 23-10-2018 IPR036681 PgpA-like superfamily GO:0006629|GO:0008962 A3L08_05915 2cc904b5d9a553826d313bd4574c6a94 138 Pfam PF04608 Phosphatidylglycerophosphatase A 13 134 2.5E-9 T 23-10-2018 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 A3L08_05915 2cc904b5d9a553826d313bd4574c6a94 138 Gene3D G3DSA:1.10.3760.10 2 137 1.1E-11 T 23-10-2018 A3L08_08575 a0a1f99f1e83e77a5b3e5b32fec95614 223 Pfam PF12840 Helix-turn-helix domain 15 70 4.0E-9 T 23-10-2018 A3L08_08575 a0a1f99f1e83e77a5b3e5b32fec95614 223 SUPERFAMILY SSF46785 7 95 5.37E-16 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L08_08575 a0a1f99f1e83e77a5b3e5b32fec95614 223 Gene3D G3DSA:1.10.10.10 9 92 1.0E-14 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L08_05525 7f4d47d8ef7926b5cd812bba21b30590 275 Gene3D G3DSA:1.25.40.10 41 217 4.1E-9 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A3L08_04610 9802313a01f98670fa93671ad966d516 269 Pfam PF14336 Domain of unknown function (DUF4392) 3 260 2.1E-64 T 23-10-2018 IPR025504 Domain of unknown function DUF4392 KEGG: 00471+4.2.1.48 A3L08_04610 9802313a01f98670fa93671ad966d516 269 Gene3D G3DSA:3.90.1640.20 1 269 1.2E-101 T 23-10-2018 A3L08_07260 a8ecf269eed89d8f82735718c7c0354d 203 SUPERFAMILY SSF75217 1 198 5.84E-65 T 23-10-2018 IPR029028 Alpha/beta knot methyltransferases A3L08_07260 a8ecf269eed89d8f82735718c7c0354d 203 Gene3D G3DSA:3.40.1280.10 1 201 9.2E-69 T 23-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal A3L08_07260 a8ecf269eed89d8f82735718c7c0354d 203 Pfam PF04013 Putative SAM-dependent RNA methyltransferase 1 198 1.9E-48 T 23-10-2018 IPR007158 tRNA (pseudouridine(54)-N(1))-methyltransferase, TrmY GO:0008175 A3L08_07260 a8ecf269eed89d8f82735718c7c0354d 203 Hamap MF_00587 tRNA (pseudouridine(54)-N(1))-methyltransferase [trmY]. 1 200 36.275 T 23-10-2018 IPR007158 tRNA (pseudouridine(54)-N(1))-methyltransferase, TrmY GO:0008175 A3L08_07355 a916db81f37bd4057337bd820e899a21 716 SMART SM00382 407 607 3.1E-7 T 23-10-2018 IPR003593 AAA+ ATPase domain A3L08_07355 a916db81f37bd4057337bd820e899a21 716 SUPERFAMILY SSF52540 396 608 4.5E-15 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_07355 a916db81f37bd4057337bd820e899a21 716 SUPERFAMILY SSF82171 26 350 1.33E-8 T 23-10-2018 A3L08_07355 a916db81f37bd4057337bd820e899a21 716 Pfam PF07728 AAA domain (dynein-related subfamily) 411 597 7.2E-14 T 23-10-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 A3L08_01325 7cbd3f83aa17d1d6a6c749f1dfdb49ca 105 TIGRFAM TIGR02179 PorD_KorD: 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate family 29 104 6.4E-34 T 23-10-2018 IPR011898 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate GO:0016625|GO:0051539 A3L08_01325 7cbd3f83aa17d1d6a6c749f1dfdb49ca 105 Pfam PF14697 4Fe-4S dicluster domain 48 100 2.6E-11 T 23-10-2018 A3L08_01325 7cbd3f83aa17d1d6a6c749f1dfdb49ca 105 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 83 94 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L08_01325 7cbd3f83aa17d1d6a6c749f1dfdb49ca 105 Gene3D G3DSA:3.30.70.20 7 105 1.1E-15 T 23-10-2018 A3L08_01325 7cbd3f83aa17d1d6a6c749f1dfdb49ca 105 SUPERFAMILY SSF54862 30 103 6.98E-23 T 23-10-2018 A3L08_05920 8b502788fe8f28c52b8f990636b2df61 231 Hamap MF_00719 Adenosylcobinamide-GDP ribazoletransferase [cobS]. 1 231 28.789 T 23-10-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 A3L08_05920 8b502788fe8f28c52b8f990636b2df61 231 Pfam PF02654 Cobalamin-5-phosphate synthase 5 221 1.8E-39 T 23-10-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 A3L08_05920 8b502788fe8f28c52b8f990636b2df61 231 TIGRFAM TIGR00317 cobS: cobalamin 5'-phosphate synthase 2 224 1.7E-44 T 23-10-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 A3L08_07155 12ffc86654bff33a38f5dcd586073774 167 Gene3D G3DSA:2.40.380.10 12 166 4.1E-13 T 23-10-2018 IPR035930 FomD-like superfamily A3L08_07155 12ffc86654bff33a38f5dcd586073774 167 SUPERFAMILY SSF159234 4 165 1.05E-38 T 23-10-2018 IPR035930 FomD-like superfamily A3L08_07155 12ffc86654bff33a38f5dcd586073774 167 Pfam PF04167 Protein of unknown function (DUF402) 56 122 1.9E-13 T 23-10-2018 IPR007295 Domain of unknown function DUF402 A3L08_04875 9f06e9b273a73ce427f85beb4a30455e 427 SUPERFAMILY SSF161070 11 350 1.31E-6 T 23-10-2018 IPR037272 Sodium:neurotransmitter symporter superfamily GO:0005328 A3L08_06610 633e3998ff1ee8ff2e202e0d9a2e40a7 276 Pfam PF04422 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term 16 89 7.2E-19 T 23-10-2018 IPR007516 Coenzyme F420 hydrogenase/dehydrogenase beta subunit, N-terminal A3L08_06610 633e3998ff1ee8ff2e202e0d9a2e40a7 276 Pfam PF04432 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus 102 249 8.7E-26 T 23-10-2018 IPR007525 Coenzyme F420 hydrogenase/dehydrogenase beta subunit, C-terminal A3L08_01795 6f7a004196076b94ba4ed802b5208b2e 330 Pfam PF00146 NADH dehydrogenase 16 324 2.1E-59 T 23-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L08_06185 930ca679ab60c14bca83c552e2d75762 193 Gene3D G3DSA:3.40.50.12280 2 163 1.8E-48 T 23-10-2018 A3L08_06185 930ca679ab60c14bca83c552e2d75762 193 SUPERFAMILY SSF56770 6 155 1.3E-49 T 23-10-2018 A3L08_06185 930ca679ab60c14bca83c552e2d75762 193 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 25 136 1.3E-18 T 23-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L08_06160 ee90bc79d6d04a465aabfad77a2a897e 210 Pfam PF06195 Protein of unknown function (DUF996) 33 184 6.3E-27 T 23-10-2018 IPR010397 Protein of unknown function DUF996 A3L08_02065 79fd60ae93ec51935a4375ab42cbc94f 179 Pfam PF01661 Macro domain 19 144 7.8E-35 T 23-10-2018 IPR002589 Macro domain A3L08_02065 79fd60ae93ec51935a4375ab42cbc94f 179 Gene3D G3DSA:3.40.220.10 1 179 3.1E-54 T 23-10-2018 A3L08_02065 79fd60ae93ec51935a4375ab42cbc94f 179 SUPERFAMILY SSF52949 2 177 1.31E-51 T 23-10-2018 A3L08_02065 79fd60ae93ec51935a4375ab42cbc94f 179 SMART SM00506 2 145 2.1E-51 T 23-10-2018 IPR002589 Macro domain A3L08_06860 a1ac1bdc10d48354fa53205a48279bf6 215 SUPERFAMILY SSF53271 7 163 4.46E-37 T 23-10-2018 IPR029057 Phosphoribosyltransferase-like A3L08_06860 a1ac1bdc10d48354fa53205a48279bf6 215 Gene3D G3DSA:3.40.50.2020 6 181 3.1E-42 T 23-10-2018 A3L08_06860 a1ac1bdc10d48354fa53205a48279bf6 215 Pfam PF00156 Phosphoribosyl transferase domain 17 152 4.1E-21 T 23-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 A3L08_03100 a217190df08c397d24f458611a538d68 356 Pfam PF00534 Glycosyl transferases group 1 144 303 1.1E-16 T 23-10-2018 IPR001296 Glycosyl transferase, family 1 A3L08_03100 a217190df08c397d24f458611a538d68 356 Gene3D G3DSA:3.40.50.2000 36 321 7.5E-33 T 23-10-2018 A3L08_03100 a217190df08c397d24f458611a538d68 356 SUPERFAMILY SSF53756 15 326 2.04E-41 T 23-10-2018 A3L08_03100 a217190df08c397d24f458611a538d68 356 Gene3D G3DSA:3.40.50.2000 130 308 7.5E-33 T 23-10-2018 A3L08_09555 3b64f533f5ffebecfdd2ebd29f022160 71 Gene3D G3DSA:2.30.30.100 2 71 7.2E-31 T 23-10-2018 A3L08_09555 3b64f533f5ffebecfdd2ebd29f022160 71 SUPERFAMILY SSF50182 6 71 4.64E-29 T 23-10-2018 IPR010920 LSM domain superfamily A3L08_07345 5edaa917868e4b8592ef4d7b840b7f3a 415 Pfam PF04409 Protein of unknown function (DUF530) 5 255 5.4E-24 T 23-10-2018 IPR007503 Protein of unknown function DUF530 A3L08_07345 5edaa917868e4b8592ef4d7b840b7f3a 415 PIRSF PIRSF018863 1 415 1.4E-190 T 23-10-2018 IPR014496 Uncharacterised conserved protein UCP018863 A3L08_01720 a57134dbfa7fab239e88357cce7987c6 118 Pfam PF07883 Cupin domain 38 104 5.4E-17 T 23-10-2018 IPR013096 Cupin 2, conserved barrel A3L08_01720 a57134dbfa7fab239e88357cce7987c6 118 Gene3D G3DSA:2.60.120.10 4 117 1.8E-34 T 23-10-2018 IPR014710 RmlC-like jelly roll fold A3L08_01720 a57134dbfa7fab239e88357cce7987c6 118 SUPERFAMILY SSF51182 6 106 4.46E-28 T 23-10-2018 IPR011051 RmlC-like cupin domain superfamily A3L08_01785 8a915c5cf45f7ff566aa22ee4e26bc2b 189 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 103 164 1.0E-26 T 23-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L08_01785 8a915c5cf45f7ff566aa22ee4e26bc2b 189 SUPERFAMILY SSF143243 21 173 7.06E-27 T 23-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L08_01785 8a915c5cf45f7ff566aa22ee4e26bc2b 189 Gene3D G3DSA:3.30.460.80 20 147 2.9E-14 T 23-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L08_01785 8a915c5cf45f7ff566aa22ee4e26bc2b 189 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 49 165 2.0E-18 T 23-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L08_00800 da328653056f60b9e7abf3dfdc86a8fd 121 SUPERFAMILY SSF46785 17 116 1.26E-15 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A3L08_00800 da328653056f60b9e7abf3dfdc86a8fd 121 Gene3D G3DSA:1.10.10.10 19 85 1.3E-13 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A3L08_00800 da328653056f60b9e7abf3dfdc86a8fd 121 Pfam PF03965 Penicillinase repressor 19 110 1.2E-15 T 23-10-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 A3L08_01870 1b1c9536ad3cba347f70ab6a8afeefd1 405 TIGRFAM TIGR04292 heavy_Cys_CGP: heavy-Cys/CGP-CTERM domain protein 19 404 1.3E-165 T 23-10-2018 IPR027556 Heavy-Cys/GCP-CTERM domain protein A3L08_01870 1b1c9536ad3cba347f70ab6a8afeefd1 405 TIGRFAM TIGR04288 CGP_CTERM: CGP-CTERM domain 387 405 2.5E-7 T 23-10-2018 IPR027552 CGP-CTERM domain A3L08_01870 1b1c9536ad3cba347f70ab6a8afeefd1 405 TIGRFAM TIGR04289 heavy_Cys: eight-cysteine-cluster domain 145 198 3.3E-23 T 23-10-2018 IPR027553 Eight-cysteine-cluster domain A3L08_06660 8c0411d53a5ae9de2d9fee938257f276 212 SUPERFAMILY SSF74784 2 182 6.41E-37 T 23-10-2018 IPR036081 Translin superfamily GO:0043565 Reactome: R-HSA-426486 A3L08_06660 8c0411d53a5ae9de2d9fee938257f276 212 Gene3D G3DSA:1.20.58.2140 4 201 1.5E-65 T 23-10-2018 A3L08_06660 8c0411d53a5ae9de2d9fee938257f276 212 Pfam PF01997 Translin family 21 177 3.6E-11 T 23-10-2018 IPR002848 Translin family GO:0043565 Reactome: R-HSA-426486 A3L08_05760 d0bb302daae40d316c57e084225065b8 273 ProDom PD039347 PF1398 MJ0538 PH1392 4 254 5.0E-85 T 23-10-2018 IPR020292 Uncharacterised protein family MJ0538 A3L08_06840 a1e44b07cc6c4c3a9772dcb77df58d19 297 Pfam PF02653 Branched-chain amino acid transport system / permease component 10 277 1.4E-34 T 23-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 A3L08_02330 aedd728294dfed1fa85eaa3505cbb4d3 509 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 342 475 2.1E-23 T 23-10-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain A3L08_02330 aedd728294dfed1fa85eaa3505cbb4d3 509 Pfam PF13440 Polysaccharide biosynthesis protein 36 340 2.7E-23 T 23-10-2018 A3L08_08580 143a7d4ad2cb60cc35b2e1876054d462 177 Gene3D G3DSA:3.10.580.10 3 175 5.1E-42 T 23-10-2018 A3L08_08580 143a7d4ad2cb60cc35b2e1876054d462 177 SUPERFAMILY SSF54631 5 133 3.28E-31 T 23-10-2018 A3L08_08580 143a7d4ad2cb60cc35b2e1876054d462 177 SMART SM00116 79 126 3.5E-9 T 23-10-2018 IPR000644 CBS domain A3L08_08580 143a7d4ad2cb60cc35b2e1876054d462 177 SMART SM00116 14 61 7.7E-9 T 23-10-2018 IPR000644 CBS domain A3L08_08580 143a7d4ad2cb60cc35b2e1876054d462 177 Pfam PF00571 CBS domain 7 60 1.8E-11 T 23-10-2018 IPR000644 CBS domain A3L08_08580 143a7d4ad2cb60cc35b2e1876054d462 177 Pfam PF00571 CBS domain 72 125 9.0E-11 T 23-10-2018 IPR000644 CBS domain A3L08_01930 503ae8059fa4d1ea8ddfaa9602a4a28d 232 Pfam PF00899 ThiF family 10 229 4.7E-53 T 23-10-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 A3L08_01930 503ae8059fa4d1ea8ddfaa9602a4a28d 232 SUPERFAMILY SSF69572 2 228 3.53E-76 T 23-10-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 A3L08_01930 503ae8059fa4d1ea8ddfaa9602a4a28d 232 Gene3D G3DSA:3.40.50.720 2 232 4.4E-70 T 23-10-2018 A3L08_00380 8a0464c37f40d011471ef13af52c9605 76 Pfam PF13244 Domain of unknown function (DUF4040) 12 72 9.7E-11 T 23-10-2018 IPR025383 Domain of unknown function DUF4040 A3L08_08495 9d429f5c02de5e8c68836067c381bd49 245 Pfam PF04016 Putative heavy-metal chelation 103 242 1.9E-34 T 23-10-2018 IPR007161 Putative heavy-metal chelation domain A3L08_08495 9d429f5c02de5e8c68836067c381bd49 245 SUPERFAMILY SSF159713 2 243 3.01E-61 T 23-10-2018 A3L08_08495 9d429f5c02de5e8c68836067c381bd49 245 Gene3D G3DSA:3.30.390.100 29 221 1.3E-24 T 23-10-2018 A3L08_08495 9d429f5c02de5e8c68836067c381bd49 245 Pfam PF13938 Putative heavy-metal chelation 10 89 1.8E-12 T 23-10-2018 IPR025251 Domain of unknown function DUF4213 A3L08_08495 9d429f5c02de5e8c68836067c381bd49 245 Gene3D G3DSA:3.40.50.11590 103 216 1.3E-24 T 23-10-2018 A3L08_01520 38ad35da3cd8718b0b3a884909f1d713 552 Pfam PF03553 Na+/H+ antiporter family 156 507 7.8E-66 T 23-10-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 A3L08_02745 4f7a938681004bf22d35162a4c96176b 376 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 6 366 3.1E-41 T 23-10-2018 IPR002823 Protein of unknown function DUF112, transmembrane A3L08_05410 6265c2a0df802b2050c4b9c9d9a0011d 819 Gene3D G3DSA:3.40.50.12610 376 502 1.1E-7 T 23-10-2018 A3L08_05410 6265c2a0df802b2050c4b9c9d9a0011d 819 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 67 220 2.3E-11 T 23-10-2018 IPR038731 Glycosyltransferase RgtA/B/C/D-like A3L08_05410 6265c2a0df802b2050c4b9c9d9a0011d 819 Gene3D G3DSA:1.50.10.20 534 760 2.2E-11 T 23-10-2018 A3L08_05410 6265c2a0df802b2050c4b9c9d9a0011d 819 SUPERFAMILY SSF48239 518 753 3.45E-13 T 23-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid A3L08_05410 6265c2a0df802b2050c4b9c9d9a0011d 819 Pfam PF06662 D-glucuronyl C5-epimerase C-terminus 686 767 2.3E-5 T 23-10-2018 IPR010598 D-glucuronyl C5-epimerase, C-terminal KEGG: 00534+5.1.3.17|MetaCyc: PWY-6558|Reactome: R-HSA-2022928 A3L08_07065 5405a6ce42ebfa89ca3f910523b3fe01 381 Pfam PF05559 Protein of unknown function (DUF763) 4 335 1.7E-119 T 23-10-2018 IPR008482 Protein of unknown function DUF763 A3L08_04785 9183f87ea15539f3e881a806b0160d21 150 Pfam PF08905 Domain of unknown function (DUF1850) 43 123 3.2E-12 T 23-10-2018 IPR015001 Protein of unknown function DUF1850 A3L08_00025 f061755d9042ad9998be99a5928c8de1 62 Gene3D G3DSA:4.10.1150.10 1 59 1.7E-5 T 23-10-2018 IPR024069 AF2212-like domain superfamily A3L08_00025 f061755d9042ad9998be99a5928c8de1 62 Pfam PF01954 Protein of unknown function DUF104 1 60 1.7E-9 T 23-10-2018 IPR008203 Uncharacterised protein family UPF0165 A3L08_00025 f061755d9042ad9998be99a5928c8de1 62 SUPERFAMILY SSF141694 1 55 7.85E-11 T 23-10-2018 A3L08_09035 5232e10aab0fe7b5ae6b417e13876ba2 143 Gene3D G3DSA:3.40.50.280 1 141 2.7E-57 T 23-10-2018 A3L08_09035 5232e10aab0fe7b5ae6b417e13876ba2 143 SUPERFAMILY SSF52242 5 133 2.75E-49 T 23-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 A3L08_09035 5232e10aab0fe7b5ae6b417e13876ba2 143 TIGRFAM TIGR00640 acid_CoA_mut_C: methylmalonyl-CoA mutase C-terminal domain 6 138 3.6E-60 T 23-10-2018 IPR006159 Methylmalonyl-CoA mutase, C-terminal GO:0016853 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 A3L08_09035 5232e10aab0fe7b5ae6b417e13876ba2 143 Pfam PF02310 B12 binding domain 8 121 2.1E-24 T 23-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 A3L08_00105 0efd41c45351e65a0ad8e84070d62c35 275 Gene3D G3DSA:3.40.1190.20 1 274 2.3E-89 T 23-10-2018 IPR029056 Ribokinase-like A3L08_00105 0efd41c45351e65a0ad8e84070d62c35 275 SUPERFAMILY SSF53613 1 265 2.18E-34 T 23-10-2018 IPR029056 Ribokinase-like A3L08_00105 0efd41c45351e65a0ad8e84070d62c35 275 Pfam PF00294 pfkB family carbohydrate kinase 183 259 4.1E-5 T 23-10-2018 IPR011611 Carbohydrate kinase PfkB A3L08_08055 98bf77488d99ab3b05c102c296039f1f 413 Pfam PF10117 McrBC 5-methylcytosine restriction system component 50 365 9.8E-25 T 23-10-2018 IPR019292 5-methylcytosine restriction system component A3L08_00265 3808b23a2e9246d15d384fd10975b6ee 189 SUPERFAMILY SSF52540 1 181 2.79E-19 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A3L08_00265 3808b23a2e9246d15d384fd10975b6ee 189 Pfam PF13207 AAA domain 6 136 5.1E-20 T 23-10-2018 A3L08_00265 3808b23a2e9246d15d384fd10975b6ee 189 Hamap MF_01111 UPF0200 protein . 2 182 31.834 T 23-10-2018 IPR022970 Nucleoside triphosphate hydrolase-related A3L08_00265 3808b23a2e9246d15d384fd10975b6ee 189 Gene3D G3DSA:3.40.50.300 1 182 2.4E-44 T 23-10-2018 A3L08_09095 964cc31be83a0d83b7b927ef1d2553bb 271 Pfam PF01889 Membrane protein of unknown function DUF63 4 269 2.2E-84 T 23-10-2018 IPR002749 Protein of unknown function DUF63 A3L08_00395 8dcd6dda097ba2c92ceb3e72ab8fb310 99 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 9 92 3.6E-16 T 23-10-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like A3L08_05950 4106f3aafba902650d9ac08c7c38522c 182 Pfam PF01955 Adenosylcobinamide amidohydrolase 3 169 2.9E-43 T 23-10-2018 IPR002808 Adenosylcobinamide amidohydrolase, CbiZ A3L08_05395 14827774a064f178dffae5e6596a0b78 99 Gene3D G3DSA:3.30.1860.10 1 97 1.4E-35 T 23-10-2018 A3L08_05395 14827774a064f178dffae5e6596a0b78 99 Pfam PF04242 Protein of unknown function (DUF424) 7 97 9.6E-34 T 23-10-2018 IPR007355 Protein of unknown function DUF424 A3L08_01790 21fd127ad26eb5b24484a7ee3e912038 426 SUPERFAMILY SSF56762 18 381 1.13E-105 T 23-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L08_01790 21fd127ad26eb5b24484a7ee3e912038 426 Gene3D G3DSA:1.10.645.20 9 381 1.8E-121 T 23-10-2018 IPR038290 NADH-quinone oxidoreductase, subunit D superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L08_01790 21fd127ad26eb5b24484a7ee3e912038 426 Pfam PF00374 Nickel-dependent hydrogenase 47 115 2.4E-13 T 23-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 A3L08_01790 21fd127ad26eb5b24484a7ee3e912038 426 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 122 381 3.2E-56 T 23-10-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L08_01805 85e12680f4012d6c88cd6ad397646867 179 SUPERFAMILY SSF47240 18 161 1.91E-22 T 23-10-2018 IPR009078 Ferritin-like superfamily A3L08_01805 85e12680f4012d6c88cd6ad397646867 179 Pfam PF02915 Rubrerythrin 24 157 5.2E-13 T 23-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 A3L08_01805 85e12680f4012d6c88cd6ad397646867 179 Gene3D G3DSA:1.20.1260.10 13 162 4.1E-28 T 23-10-2018 IPR012347 Ferritin-like A3L08_07600 294338cddc36f59c62447c748b72c008 290 Gene3D G3DSA:3.30.2010.10 62 150 2.0E-33 T 23-10-2018 A3L08_07600 294338cddc36f59c62447c748b72c008 290 Pfam PF01435 Peptidase family M48 68 282 7.7E-38 T 23-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 A3L08_07600 294338cddc36f59c62447c748b72c008 290 Hamap MF_00188 Protease HtpX [htpX]. 6 282 30.236 T 23-10-2018 IPR022919 Peptidase M48, protease HtpX, putative GO:0004222 A3L08_03975 1ebbf88299d80976b78249fc6d9b7c4f 222 Pfam PF03192 Pyrococcus protein of unknown function, DUF257 8 204 1.4E-55 T 23-10-2018 IPR005489 Protein of unknown function DUF257 A3L08_03975 1ebbf88299d80976b78249fc6d9b7c4f 222 Gene3D G3DSA:3.40.50.11570 4 209 1.3E-50 T 23-10-2018 A3L08_03355 8382fce2b32348798363aa26407d1c9c 193 SUPERFAMILY SSF53335 3 180 5.78E-42 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A3L08_03355 8382fce2b32348798363aa26407d1c9c 193 Gene3D G3DSA:3.40.50.150 14 192 4.4E-40 T 23-10-2018 A3L08_03355 8382fce2b32348798363aa26407d1c9c 193 TIGRFAM TIGR00537 hemK_rel_arch: putative methylase 15 189 4.6E-61 T 23-10-2018 IPR004557 Eukaryotic/archaeal PrmC-related GO:0008276 Reactome: R-HSA-156581|Reactome: R-HSA-72764 A3L08_03355 8382fce2b32348798363aa26407d1c9c 193 Pfam PF05175 Methyltransferase small domain 22 164 6.5E-19 T 23-10-2018 IPR007848 Methyltransferase small domain GO:0008168 A3L08_07820 4316839b9e7770556037767b4a9744e2 292 SUPERFAMILY SSF48239 9 251 1.29E-15 T 23-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid A3L08_07820 4316839b9e7770556037767b4a9744e2 292 PIRSF PIRSF016175 7 286 4.0E-129 T 23-10-2018 IPR016648 Uncharacterised conserved protein UCP016175, prenyltransferase beta-subunit-related A3L08_01905 d45be66c02127f248b132f1b6e5c2149 162 Pfam PF04008 Adenosine specific kinase 7 160 3.3E-62 T 23-10-2018 IPR007153 Adenosine specific kinase A3L08_01905 d45be66c02127f248b132f1b6e5c2149 162 Gene3D G3DSA:3.40.1520.10 1 162 4.5E-72 T 23-10-2018 IPR036902 Ta1353-like superfamily A3L08_01905 d45be66c02127f248b132f1b6e5c2149 162 SUPERFAMILY SSF103165 2 160 2.22E-60 T 23-10-2018 IPR036902 Ta1353-like superfamily A3L08_01115 95cc708c045130d32b05f697ff2fb0d0 352 Pfam PF05763 Protein of unknown function (DUF835) 228 350 9.1E-36 T 23-10-2018 IPR008553 Domain of unknown function DUF835 A3L08_01205 cbc91cce02b35038cc58488f47927f6c 428 Pfam PF03600 Citrate transporter 18 368 2.3E-54 T 23-10-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 A3L08_01205 cbc91cce02b35038cc58488f47927f6c 428 PRINTS PR00758 Arsenical pump membrane protein signature 324 346 1.9E-14 T 23-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 A3L08_01205 cbc91cce02b35038cc58488f47927f6c 428 PRINTS PR00758 Arsenical pump membrane protein signature 364 389 1.9E-14 T 23-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 A3L08_01205 cbc91cce02b35038cc58488f47927f6c 428 PRINTS PR00758 Arsenical pump membrane protein signature 223 248 1.9E-14 T 23-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 A3L08_01205 cbc91cce02b35038cc58488f47927f6c 428 PRINTS PR00758 Arsenical pump membrane protein signature 280 304 1.9E-14 T 23-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 A3L08_01205 cbc91cce02b35038cc58488f47927f6c 428 PRINTS PR00758 Arsenical pump membrane protein signature 397 421 1.9E-14 T 23-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 A3L08_01205 cbc91cce02b35038cc58488f47927f6c 428 PRINTS PR00758 Arsenical pump membrane protein signature 103 127 1.9E-14 T 23-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 A3L08_09735 96f6b05f462de9ac56987bcc18e6edd4 401 Gene3D G3DSA:1.20.120.1220 50 170 3.8E-14 T 23-10-2018 A3L08_09735 96f6b05f462de9ac56987bcc18e6edd4 401 Pfam PF06819 Archaeal Peptidase A24 C-terminal Domain 257 365 1.2E-28 T 23-10-2018 IPR009639 Peptidase A24A-predicted, C-terminal archaea A3L08_06495 b4d92ecd5572eabc6769417ed0add4f1 367 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 233 244 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L08_06495 b4d92ecd5572eabc6769417ed0add4f1 367 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 312 323 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A3L08_06495 b4d92ecd5572eabc6769417ed0add4f1 367 SUPERFAMILY SSF46548 216 332 4.76E-12 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 A3L08_06495 b4d92ecd5572eabc6769417ed0add4f1 367 Pfam PF17179 4Fe-4S dicluster domain 233 326 2.3E-27 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A3L08_01375 c5a055fe5c36bb372a752f5fe3506bf2 272 PIRSF PIRSF006648 19 264 9.9E-15 T 23-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A3L08_01375 c5a055fe5c36bb372a752f5fe3506bf2 272 PRINTS PR00164 ABC-2 type transport system membrane protein signature 186 205 4.4E-5 T 23-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A3L08_01375 c5a055fe5c36bb372a752f5fe3506bf2 272 PRINTS PR00164 ABC-2 type transport system membrane protein signature 206 225 4.4E-5 T 23-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A3L08_01375 c5a055fe5c36bb372a752f5fe3506bf2 272 PRINTS PR00164 ABC-2 type transport system membrane protein signature 149 173 4.4E-5 T 23-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A3L08_01375 c5a055fe5c36bb372a752f5fe3506bf2 272 Pfam PF01061 ABC-2 type transporter 24 227 4.6E-16 T 23-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 A3L08_02165 e6568025b19771faef8450b65b51849f 111 TIGRFAM TIGR04076 TIGR04076: TIGR04076 family protein 1 96 1.3E-19 T 23-10-2018 IPR023811 Conserved hypothetical protein CHP04076 A3L08_06515 347019e520f72fcbcb092b155b23d6d6 593 Pfam PF00361 Proton-conducting membrane transporter 106 388 2.7E-55 T 23-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L08_06515 347019e520f72fcbcb092b155b23d6d6 593 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 209 233 1.2E-8 T 23-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L08_06515 347019e520f72fcbcb092b155b23d6d6 593 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 353 379 1.2E-8 T 23-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L08_06515 347019e520f72fcbcb092b155b23d6d6 593 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 302 321 1.2E-8 T 23-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L08_06515 347019e520f72fcbcb092b155b23d6d6 593 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 144 168 1.2E-8 T 23-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L08_01970 f4599ed153fbe5338c8bb8c4f626c26f 256 Pfam PF05763 Protein of unknown function (DUF835) 126 253 4.5E-32 T 23-10-2018 IPR008553 Domain of unknown function DUF835 A3L08_02870 0b517254dc78f0bcfe97671a8804c6a1 258 ProDom PD359573 MEMBRANE TRANSMEMBRANE AF2132 PROTEIN 5 256 7.0E-124 T 23-10-2018 A3L08_01165 b9b094223952355f2079068214047267 214 Pfam PF03192 Pyrococcus protein of unknown function, DUF257 10 203 1.3E-46 T 23-10-2018 IPR005489 Protein of unknown function DUF257 A3L08_01165 b9b094223952355f2079068214047267 214 Gene3D G3DSA:3.40.50.11570 3 212 4.8E-53 T 23-10-2018 A3L08_01090 ef8ba81448e43ae598c4c98699231a95 194 Gene3D G3DSA:1.10.1760.20 1 193 1.1E-17 T 23-10-2018 A3L08_00010 70e0853070009f692938b3a05dea5599 427 Gene3D G3DSA:1.25.40.10 314 410 3.2E-9 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A3L08_01430 484808d3ca0819f92e046843e184be82 211 Pfam PF04252 Predicted SAM-dependent RNA methyltransferase 5 188 3.9E-43 T 23-10-2018 IPR007364 RNA methyltransferase TK0422/Sfm1 GO:0008168 A3L08_03065 d3f66759d851d9269ffae183d80577ca 509 Pfam PF01943 Polysaccharide biosynthesis protein 12 280 5.1E-33 T 23-10-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 A3L08_03065 d3f66759d851d9269ffae183d80577ca 509 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 342 477 3.8E-22 T 23-10-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain A3L08_04325 4bf9a1373bbfc09c0251e0605b2dc6bf 166 Pfam PF03692 Putative zinc- or iron-chelating domain 25 131 9.8E-20 T 23-10-2018 IPR005358 Putative zinc- or iron-chelating domain containing protein A3L08_03300 7db93066e8a87a1328935dc92c195284 248 Pfam PF09874 Predicted membrane protein (DUF2101) 22 228 7.6E-76 T 23-10-2018 IPR018663 Protein of unknown function DUF2101, membrane A3L08_06955 a667220d70772d84624abcb0faee79ba 335 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 125 330 3.4E-32 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A3L08_06510 17907a46182151d2b32bfea04cfc5894 474 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 155 176 5.6E-24 T 23-10-2018 A3L08_06510 17907a46182151d2b32bfea04cfc5894 474 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 238 264 5.6E-24 T 23-10-2018 A3L08_06510 17907a46182151d2b32bfea04cfc5894 474 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 109 129 5.6E-24 T 23-10-2018 A3L08_06510 17907a46182151d2b32bfea04cfc5894 474 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 74 99 5.6E-24 T 23-10-2018 A3L08_06510 17907a46182151d2b32bfea04cfc5894 474 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 216 237 5.6E-24 T 23-10-2018 A3L08_06510 17907a46182151d2b32bfea04cfc5894 474 Pfam PF00361 Proton-conducting membrane transporter 133 408 5.9E-46 T 23-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L08_02995 293ff655cb4c028763e10b510a5e8035 427 Pfam PF01882 Protein of unknown function DUF58 181 261 3.0E-14 T 23-10-2018 IPR002881 Domain of unknown function DUF58 A3L08_05805 75bdf07f5750ab969e8046340e359c85 439 Pfam PF00999 Sodium/hydrogen exchanger family 12 404 1.7E-45 T 23-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 A3L08_05805 75bdf07f5750ab969e8046340e359c85 439 Gene3D G3DSA:1.20.1530.20 5 416 8.4E-68 T 23-10-2018 IPR038770 Sodium/solute symporter superfamily A3L08_06140 60e4d13a54a0e3daa3a66cde20ed760b 270 SUPERFAMILY SSF100950 12 120 8.27E-7 T 23-10-2018 IPR037171 NagB/RpiA transferase-like A3L08_01435 3f6645e481888793fd06dc1de1e0d853 97 Pfam PF09876 Predicted metal-binding protein (DUF2103) 5 92 1.4E-21 T 23-10-2018 IPR018664 Protein of unknown function DUF2103, metal-binding A3L08_07510 19cc93345b66ea9f26becca4edcf37cb 280 Pfam PF00892 EamA-like transporter family 149 270 4.2E-12 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A3L08_07510 19cc93345b66ea9f26becca4edcf37cb 280 Pfam PF00892 EamA-like transporter family 6 140 3.3E-18 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A3L08_07510 19cc93345b66ea9f26becca4edcf37cb 280 SUPERFAMILY SSF103481 182 271 4.97E-8 T 23-10-2018 A3L08_07510 19cc93345b66ea9f26becca4edcf37cb 280 SUPERFAMILY SSF103481 41 143 3.01E-11 T 23-10-2018 A3L08_05865 3c0bb7334f8b87b4aecd34ff0d1b2e33 564 Pfam PF03553 Na+/H+ antiporter family 167 496 1.8E-74 T 23-10-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 A3L08_08365 22f6c79f502fc557cf31122320bc9b77 247 Pfam PF12730 ABC-2 family transporter protein 55 176 1.5E-6 T 23-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 A3L08_03515 2d53abd039a714905c4f798ec314747c 100 Pfam PF11537 Protein of unknown function (DUF3227) 9 92 4.1E-24 T 23-10-2018 IPR021609 Protein of unknown function DUF3227 A3L08_03515 2d53abd039a714905c4f798ec314747c 100 Gene3D G3DSA:1.10.1200.200 6 100 1.8E-23 T 23-10-2018 A3L08_07905 a7d8b19b6c0458b1c0f4a1909d2fa7a3 136 Pfam PF12646 Domain of unknown function (DUF3783) 58 113 1.3E-14 T 23-10-2018 IPR016621 Uncharacterised conserved protein UCP014543 A3L08_07905 a7d8b19b6c0458b1c0f4a1909d2fa7a3 136 PIRSF PIRSF014543 1 123 3.1E-39 T 23-10-2018 IPR016621 Uncharacterised conserved protein UCP014543 A3L08_08665 b41538beed5e18f6e1d287c9d0b2d8ef 457 Pfam PF10117 McrBC 5-methylcytosine restriction system component 56 382 2.0E-63 T 23-10-2018 IPR019292 5-methylcytosine restriction system component A3L08_03115 b51835aad269d968017e5455c9aae050 69 Gene3D G3DSA:3.90.550.10 1 69 4.2E-6 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A3L08_03115 b51835aad269d968017e5455c9aae050 69 Pfam PF00535 Glycosyl transferase family 2 6 66 1.6E-5 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A3L08_05495 11072cc61d8cedfc962da8211124291b 367 Pfam PF05763 Protein of unknown function (DUF835) 229 365 1.8E-33 T 23-10-2018 IPR008553 Domain of unknown function DUF835 A3L08_01590 2ff43c06f80de0fa8f2adfe33b58b015 318 Pfam PF01939 Endonuclease NucS 215 281 7.9E-5 T 23-10-2018 IPR002793 Endonuclease NucS GO:0004519 A3L08_01590 2ff43c06f80de0fa8f2adfe33b58b015 318 Gene3D G3DSA:3.40.1350.10 207 288 6.6E-9 T 23-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 A3L08_07875 0d939af29eb9fe21a00de9c2e62c3fff 358 Pfam PF05763 Protein of unknown function (DUF835) 229 353 3.4E-33 T 23-10-2018 IPR008553 Domain of unknown function DUF835 A3L08_02045 38df24e0a827a03b5acce1869201faf0 127 Pfam PF04322 Protein of unknown function (DUF473) 1 111 4.2E-31 T 23-10-2018 IPR007417 Protein of unknown function DUF473 A3L08_02045 38df24e0a827a03b5acce1869201faf0 127 ProDom PD020987 PF0014 UNCHARACTERIZED AF1250 PH0127 MJ0105 MA4414 ARCHAEAL 1 104 3.0E-34 T 23-10-2018 IPR007417 Protein of unknown function DUF473 A3L08_01710 367e0ff175e54ce9a2ef8e16d70287a5 403 Pfam PF01384 Phosphate transporter family 19 392 3.0E-111 T 23-10-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 A3L08_06325 f1c11f2a9cd138dbdeaac7a8db6d4dac 152 Pfam PF04021 Class III signal peptide 2 24 5.0E-6 T 23-10-2018 IPR007166 Class III signal peptide motif A3L08_07555 22f6f7ba7f7e42ef8d2a650534d9e1bf 308 Pfam PF12679 ABC-2 family transporter protein 5 307 3.8E-62 T 23-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 A3L08_02510 1f64de4f651a53a7ac89de809b8b8bff 188 Pfam PF03729 Short repeat of unknown function (DUF308) 16 85 1.2E-10 T 23-10-2018 IPR005325 Protein of unknown function DUF308, membrane A3L08_02510 1f64de4f651a53a7ac89de809b8b8bff 188 Pfam PF03729 Short repeat of unknown function (DUF308) 78 141 3.9E-5 T 23-10-2018 IPR005325 Protein of unknown function DUF308, membrane A3L08_09520 6f177ef05288e0376a018e3989b0db25 263 Pfam PF12679 ABC-2 family transporter protein 7 202 8.0E-17 T 23-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 A3L08_07310 a9730ca3e4a1f76e7b878cdfd9d70ebf 273 SUPERFAMILY SSF81345 4 272 1.57E-18 T 23-10-2018 IPR037294 ABC transporter, BtuC-like A3L08_07310 a9730ca3e4a1f76e7b878cdfd9d70ebf 273 Pfam PF00950 ABC 3 transport family 4 268 1.8E-26 T 23-10-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 A3L08_01300 ee851a4131f3e6ace379a26427a88c27 320 Pfam PF01384 Phosphate transporter family 19 307 2.2E-70 T 23-10-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 A3L08_02205 6ad3997f472f10d5996bfedbed7b37bf 283 Pfam PF13559 Domain of unknown function (DUF4129) 207 273 6.6E-9 T 23-10-2018 IPR025403 Domain of unknown function DUF4129 A3L08_03305 51db158107b796fce76b1aff25f90822 1072 Pfam PF10102 Domain of unknown function (DUF2341) 536 592 3.1E-6 T 23-10-2018 IPR018765 Domain of unknown function DUF2341 A3L08_07525 4a9d9f929246ce72b468c773392cd18e 86 Pfam PF01402 Ribbon-helix-helix protein, copG family 6 41 9.5E-7 T 23-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 A3L08_01760 3b55b31e2aa50c0272dc128edc315e4c 144 Pfam PF04039 Domain related to MnhB subunit of Na+/H+ antiporter 4 130 3.1E-25 T 23-10-2018 IPR007182 Na+/H+ antiporter MnhB subunit-related protein A3L08_06200 2406079edcffd703542c1ac587ac0212 495 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 413 432 2.8E-9 T 23-10-2018 A3L08_06200 2406079edcffd703542c1ac587ac0212 495 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 78 103 2.8E-9 T 23-10-2018 A3L08_06200 2406079edcffd703542c1ac587ac0212 495 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 216 237 2.8E-9 T 23-10-2018 A3L08_06200 2406079edcffd703542c1ac587ac0212 495 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 151 172 2.8E-9 T 23-10-2018 A3L08_06200 2406079edcffd703542c1ac587ac0212 495 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 309 321 2.8E-9 T 23-10-2018 A3L08_06200 2406079edcffd703542c1ac587ac0212 495 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 238 264 2.8E-9 T 23-10-2018 A3L08_06200 2406079edcffd703542c1ac587ac0212 495 Pfam PF00361 Proton-conducting membrane transporter 129 416 3.1E-63 T 23-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L08_08170 ca090888307934f802703973968a5661 109 Gene3D G3DSA:3.40.1260.10 1 109 5.0E-15 T 23-10-2018 IPR027396 DsrEFH-like A3L08_01830 e856ffaa0fdb04f5326bdca075e28398 176 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 6 170 5.1E-13 T 23-10-2018 IPR007404 LexA-binding, inner membrane-associated putative hydrolase A3L08_06450 154171f3786b6468707c48b872427b4d 446 SUPERFAMILY SSF101960 16 442 6.02E-103 T 23-10-2018 IPR037284 SUF system FeS cluster assembly, SufBD superfamily A3L08_06450 154171f3786b6468707c48b872427b4d 446 Pfam PF01458 Uncharacterized protein family (UPF0051) 195 418 2.1E-53 T 23-10-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 A3L08_04775 c61b260f5a5df22f03888fac10310cdc 402 SUPERFAMILY SSF53743 1 281 8.89E-39 T 23-10-2018 IPR009015 L-fucose isomerase, N-terminal/central domain superfamily GO:0005737|GO:0005996|GO:0016861 A3L08_07885 fbd39bea3048d6ef1f8f4f86ee24c214 153 Pfam PF06695 Putative small multi-drug export protein 17 143 1.1E-29 T 23-10-2018 IPR009577 Putative small multi-drug export A3L08_06115 7eba0442c557cce105d9cc0aad07611f 91 Gene3D G3DSA:1.20.1280.290 1 86 3.7E-9 T 23-10-2018 A3L08_05235 000bd82daa2805251fb405984e6070d2 338 Gene3D G3DSA:1.20.1530.20 10 323 5.2E-46 T 23-10-2018 IPR038770 Sodium/solute symporter superfamily A3L08_05235 000bd82daa2805251fb405984e6070d2 338 Pfam PF01758 Sodium Bile acid symporter family 48 233 2.8E-36 T 23-10-2018 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 A3L08_02260 481009cd5aa1a23fc6a1a1f447865180 669 Pfam PF04312 Protein of unknown function (DUF460) 210 350 2.3E-48 T 23-10-2018 IPR007408 Protein of unknown function DUF460 A3L08_06205 5293092a21e5addb2d9731013e5257f0 114 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 5 111 1.8E-31 T 23-10-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like A3L08_06520 e8fabb1a020b8c2ad877febc320dc78e 292 Pfam PF00146 NADH dehydrogenase 10 286 6.9E-37 T 23-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A3L08_06215 6cf58dcb37c053f7173b643bc37fb2cb 94 Pfam PF13244 Domain of unknown function (DUF4040) 13 79 4.1E-20 T 23-10-2018 IPR025383 Domain of unknown function DUF4040 A3L08_02750 c9d5f3869e8e4c9f8d683efea4d6516c 102 Gene3D G3DSA:3.30.720.70 1 102 1.7E-45 T 23-10-2018 A3L08_07110 68f3ae5ee2285238299bde1b8f8db668 217 Pfam PF13349 Putative adhesin 86 214 3.8E-7 T 23-10-2018 IPR025164 Putative adhesin A3L08_06350 668bdde87427e1f3021b790dd611c48f 418 Pfam PF02163 Peptidase family M50 305 344 7.1E-7 T 23-10-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 A3L08_03390 ced9ad0de9f178769554a65ec4c87065 334 Pfam PF17231 Family of unknown function (DUF5305) 120 322 2.4E-10 T 23-10-2018 IPR035185 Protein of unknown function DUF5305 A3L08_05485 13075c924a56f7b084e352fd8403d216 271 Pfam PF02673 Bacitracin resistance protein BacA 11 254 1.5E-22 T 23-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 A3L08_05585 522a9b1852ed0f7816df2f6d68e40e35 210 Pfam PF09840 Uncharacterized protein conserved in archaea (DUF2067) 10 197 9.7E-53 T 23-10-2018 IPR019202 Protein of unknown function DUF2067 A3L08_04530 3392d1ee97d477ce6460939e649fcfa3 387 Gene3D G3DSA:3.40.50.300 1 183 4.1E-13 T 23-10-2018 A3L08_07235 d324e7933434f132880b488332b65a76 120 Pfam PF09685 Domain of unknown function (DUF4870) 25 106 1.1E-10 T 23-10-2018 IPR019109 Protein of unknown function DUF4870 A3L08_05160 748def20fd021b75d1c6246281a27253 82 ProDom PD486863 PRECURSOR CBIM SIGNAL COBALT MEMBRANE VITAMIN B12 BIOSYNTHESIS COBALAMIN ABC-TYPE 23 81 0.002 T 23-10-2018 A3L08_02440 ada6d5efdb5c377086a39d29ae15d924 204 Pfam PF01914 MarC family integral membrane protein 7 196 1.4E-29 T 23-10-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 A3L08_00495 709b3a88c1c59f1bf6e7e0739d650155 569 Pfam PF04458 Protein of unknown function (DUF505) 1 300 1.8E-75 T 23-10-2018 IPR007548 Protein of unknown function DUF505 A3L08_00495 709b3a88c1c59f1bf6e7e0739d650155 569 Pfam PF04458 Protein of unknown function (DUF505) 306 566 1.1E-80 T 23-10-2018 IPR007548 Protein of unknown function DUF505 A3L08_00370 7f9310788cb1249147d6b63e1b88389e 91 Pfam PF04066 Multiple resistance and pH regulation protein F (MrpF / PhaF) 32 84 4.3E-15 T 23-10-2018 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 A3L08_02170 2cbd899387e599cc7e3f818f58a580b9 481 Pfam PF04415 Protein of unknown function (DUF515) 29 480 3.9E-143 T 23-10-2018 IPR007509 Protein of unknown function DUF515 A3L08_07425 b9157e01470bb41c075db25b64d93f87 59 SUPERFAMILY SSF47113 6 59 7.88E-6 T 23-10-2018 IPR009072 Histone-fold GO:0046982 A3L08_02855 3bb889b4b11bbcb204751dabe20a505b 258 ProDom PD359573 MEMBRANE TRANSMEMBRANE AF2132 PROTEIN 57 256 4.0E-14 T 23-10-2018