locus-tag	class	description
TES1_0007	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
TES1_0014	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
TES1_0020	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
TES1_0021	ENOG4105M7V	2'-5' rna ligase
TES1_0037	ENOG4108K16	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
TES1_0040	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
TES1_0044	ENOG4107RFW	hydrolase family 57
TES1_0045	ENOG4108YZA	Nitrogen regulatory protein pii
TES1_0047	ENOG4105C8J	)-transporter
TES1_0048	ENOG4105D82	Glutamate dehydrogenase
TES1_0050	ENOG4105KPK	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation (By similarity)
TES1_0051	ENOG4105CY0	Metallo-Beta-Lactamase
TES1_0054	ENOG4105E66	phosphoriboisomerase A
TES1_0056	ENOG4105CPP	Dehydrogenase, E1 component
TES1_0057	ENOG4107RUY	(E1 component), alpha subunit
TES1_0058	ENOG4107QKR	Dehydrogenase
TES1_0059	ENOG4105C7S	Dehydrogenase
TES1_0061	ENOG4106Z86	ATP-nad acox kinase
TES1_0062	ENOG4105DF9	Lipoate-protein, ligase
TES1_0063	ENOG4105UQX	Mate efflux family protein
TES1_0064	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
TES1_0069	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
TES1_0076	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
TES1_0078	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
TES1_0083	ENOG4105Q33	Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency
TES1_0084	ENOG4105E0A	ABC, transporter
TES1_0085	ENOG4105EHG	Permease protein
TES1_0086	ENOG4105S10	periplasmic binding protein
TES1_0089	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
TES1_0093	ENOG4105CQS	hydrogenase expression formation protein HypD
TES1_0095	ENOG41067SE	Tetr family transcriptional regulator
TES1_0096	ENOG4108IEG	Formate dehydrogenase Alpha subunit
TES1_0097	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
TES1_0098	ENOG4105D65	subunit l
TES1_0099	ENOG4108JPZ	Monovalent cation H antiporter subunit D
TES1_0100	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
TES1_0101	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
TES1_0102	ENOG4108RG7	formate hydrogenlyase complex iron-sulfur subunit
TES1_0103	ENOG4105C47	NADH ubiquinone oxidoreductase 20 kda subunit
TES1_0106	ENOG4105KJM	monovalent cation h antiporter subunit g
TES1_0109	ENOG4108ZE9	Monovalent cation H antiporter subunit C
TES1_0111	ENOG4108JPZ	Monovalent cation H antiporter subunit D
TES1_0114	ENOG4105EHG	Permease protein
TES1_0115	ENOG4108HWH	(ABC) transporter
TES1_0116	ENOG4105CTK	cobaltochelatase, cobn subunit
TES1_0117	ENOG4105EET	magnesium chelatase
TES1_0120	ENOG4105C4K	Nad synthetase
TES1_0122	ENOG41083NF	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
TES1_0125	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
TES1_0128	ENOG4108Z4T	Peptidase M50
TES1_0129	ENOG4108Y83	glucose-6-phosphate isomerase
TES1_0134	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
TES1_0138	ENOG4108JJB	ABC transporter
TES1_0141	ENOG4105CFT	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import (By similarity)
TES1_0150	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
TES1_0151	ENOG4105DBV	ornithine carbamoyltransferase
TES1_0152	ENOG41087GE	Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity)
TES1_0154	ENOG4105E3H	phosphoglycerate mutase
TES1_0158	ENOG4105C5R	Aminotransferase
TES1_0160	ENOG4105C5S	asparaginyl-tRNA synthetase
TES1_0161	ENOG4107Y03	Nitroreductase
TES1_0162	ENOG4105BZ8	glutamate synthase
TES1_0163	ENOG4105CDJ	oxidoreductase FAD NAD(P)-binding domain protein
TES1_0165	ENOG4105DF0	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity)
TES1_0173	ENOG4105CKX	Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP
TES1_0179	ENOG4105D8K	carboxyl transferase
TES1_0181	ENOG4107QSA	Oxaloacetate decarboxylase
TES1_0182	ENOG4105D9Q	decarboxylase (Beta subunit)
TES1_0183	ENOG4105CJW	magnesium transporter
TES1_0184	ENOG4105D6E	homoserine dehydrogenase
TES1_0191	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
TES1_0193	ENOG4105KZR	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
TES1_0194	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
TES1_0195	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
TES1_0197	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
TES1_0198	ENOG41082SA	50s ribosomal protein l29
TES1_0199	ENOG4108ZJT	translation initiation factor, Sui1
TES1_0201	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
TES1_0202	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
TES1_0203	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
TES1_0205	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
TES1_0207	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
TES1_0208	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
TES1_0211	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
TES1_0213	ENOG410849U	50S ribosomal protein L30
TES1_0214	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
TES1_0219	ENOG4108Z4J	Cytidine monophosphate kinase
TES1_0221	ENOG4105CHR	reductase
TES1_0222	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
TES1_0223	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
TES1_0224	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
TES1_0225	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
TES1_0227	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
TES1_0228	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
TES1_0229	ENOG4108UJD	30S ribosomal protein S9
TES1_0232	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
TES1_0233	ENOG4105CE9	30S ribosomal protein S2
TES1_0234	ENOG41074MP	UPF0103 Mediator of ErbB2-driven cell motility-containing protein
TES1_0235	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
TES1_0236	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
TES1_0237	ENOG4106UJV	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
TES1_0241	ENOG4105C8T	Leucyl-tRNA synthetase
TES1_0246	ENOG4105C28	cystathionine
TES1_0250	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
TES1_0252	ENOG4108JEB	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
TES1_0254	ENOG4105F7N	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation (By similarity)
TES1_0257	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
TES1_0258	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
TES1_0267	ENOG4105BZR	domain protein
TES1_0270	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
TES1_0271	ENOG4105CV8	reductase
TES1_0273	ENOG4108T9Q	UPF0278 protein
TES1_0280	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
TES1_0283	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
TES1_0284	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
TES1_0288	ENOG4105DHP	deoxycytidine triphosphate deaminase
TES1_0293	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
TES1_0295	ENOG4105CNB	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
TES1_0296	ENOG4105C0M	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity)
TES1_0299	ENOG4107R76	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
TES1_0301	ENOG4105CX6	glutaminyL-tRNA synthetase
TES1_0304	ENOG4107TE1	transport protein
TES1_0306	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
TES1_0307	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
TES1_0310	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
TES1_0321	ENOG4107B2H	carbonic anhydrase
TES1_0324	ENOG4107RGW	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
TES1_0327	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
TES1_0329	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
TES1_0333	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
TES1_0334	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
TES1_0336	ENOG4108IYI	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
TES1_0337	ENOG4108I5U	Uridine phosphorylase
TES1_0338	ENOG4105CB1	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
TES1_0341	ENOG41079KZ	Major Facilitator Superfamily
TES1_0345	ENOG4108UPS	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis (By similarity)
TES1_0347	ENOG4105FKN	transcriptional regulator, AsnC family
TES1_0363	ENOG4105D22	carbon starvation protein
TES1_0364	ENOG4107QSA	Oxaloacetate decarboxylase
TES1_0365	ENOG41061GT	Aldolase
TES1_0366	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
TES1_0369	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
TES1_0370	ENOG4105VZ9	UPF0235 protein
TES1_0372	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
TES1_0376	ENOG4105UQX	Mate efflux family protein
TES1_0378	ENOG4108K3F	N(2),N(2)-dimethylguanosine tRNA methyltransferase
TES1_0380	ENOG4105DC7	peptidase M24
TES1_0382	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
TES1_0383	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
TES1_0386	ENOG4105CE1	Ferrous iron transport protein b
TES1_0390	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
TES1_0391	ENOG4108VVK	transcriptional Regulator, AsnC
TES1_0395	ENOG4105C3G	gtp-binding protein
TES1_0398	ENOG4105D7N	magnesium and cobalt transport protein CorA
TES1_0405	ENOG4105U0R	haloacid dehalogenase-like hydrolase
TES1_0407	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
TES1_0414	ENOG4108J2R	molybdopterin oxidoreductase
TES1_0415	ENOG4105D3R	alkyl hydroperoxide reductase
TES1_0421	ENOG4105DQU	oxidoreductase, subunit beta
TES1_0422	ENOG4105D3R	alkyl hydroperoxide reductase
TES1_0423	ENOG4105CNW	domain protein
TES1_0424	ENOG4108EQM	faD-dependent pyridine nucleotide-disulfide oxidoreductase
TES1_0425	ENOG4108RAC	Rubrerythrin
TES1_0426	ENOG4105VCQ	rubredoxin
TES1_0427	ENOG4108YZ8	Superoxide reductase
TES1_0433	ENOG4105EHU	Circadian clock protein KaiC
TES1_0444	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
TES1_0449	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
TES1_0454	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
TES1_0461	ENOG4105HDK	L-asparaginase
TES1_0462	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
TES1_0467	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
TES1_0468	ENOG4105CPQ	Dehydrogenase
TES1_0469	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
TES1_0472	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
TES1_0473	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
TES1_0474	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
TES1_0476	ENOG4107QK3	aspartate-semialdehyde dehydrogenase (EC 1.2.1.11
TES1_0477	ENOG4108IYI	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
TES1_0478	ENOG4107RDY	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
TES1_0479	ENOG4105CFH	Aspartokinase
TES1_0481	ENOG4108HHA	Transketolase
TES1_0482	ENOG4108IUS	Transketolase
TES1_0483	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
TES1_0486	ENOG4105E2X	shikimate dehydrogenase
TES1_0487	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
TES1_0488	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
TES1_0489	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
TES1_0491	ENOG4105CHM	Aminotransferase
TES1_0493	ENOG4105C59	p-type ATPase
TES1_0495	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
TES1_0496	ENOG4108YZA	Nitrogen regulatory protein pii
TES1_0498	ENOG4105CDH	Citrulline--aspartate ligase
TES1_0499	ENOG4105CH7	arginosuccinase
TES1_0500	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
TES1_0502	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
TES1_0503	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
TES1_0504	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
TES1_0505	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
TES1_0507	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
TES1_0508	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
TES1_0509	ENOG4105CAS	nag kinase
TES1_0510	ENOG4105C8Y	Acetylornithine aminotransferase
TES1_0511	ENOG4108KB0	deacetylase
TES1_0513	ENOG4105CIH	Imidazole acetol-phosphate transaminase
TES1_0514	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
TES1_0515	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
TES1_0516	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
TES1_0517	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
TES1_0518	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
TES1_0520	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
TES1_0524	ENOG4105EEI	dihydropteroate synthase
TES1_0527	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
TES1_0530	ENOG4105DRS	transport system, permease
TES1_0531	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
TES1_0538	ENOG41066FR	extracellular solute-binding protein
TES1_0539	ENOG4105E0C	molybdate abc transporter
TES1_0540	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
TES1_0542	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
TES1_0543	ENOG4105CEV	competence damage-inducible protein
TES1_0544	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
TES1_0547	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
TES1_0548	ENOG4105KJJ	Uncharacterized ACR, COG1993
TES1_0549	ENOG4105WMR	Protein CrcB homolog
TES1_0555	ENOG4107QJZ	Glycosyl transferase, family 2
TES1_0564	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
TES1_0565	ENOG4105C6E	dna polymerase iii
TES1_0567	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
TES1_0573	ENOG4107WZZ	SMC domain protein
TES1_0573	ENOG4107WZZ	SMC domain protein
TES1_0575	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
TES1_0577	ENOG4105CND	Glycosyl transferase, family 2
TES1_0579	ENOG4108IUQ	atp-dependent protease
TES1_0581	ENOG4105KME	endoribonuclease L-psp
TES1_0586	ENOG4108ZPQ	MazG nucleotide pyrophosphohydrolase
TES1_0589	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
TES1_0590	ENOG4105DQW	permease for cytosine purines, uracil, thiamine, allantoin
TES1_0591	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
TES1_0592	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
TES1_0593	ENOG4105DWF	phosphomethylpyrimidine kinase
TES1_0594	ENOG4105FDK	ABC transporter
TES1_0596	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
TES1_0598	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
TES1_0601	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
TES1_0602	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
TES1_0605	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
TES1_0610	ENOG4108JU3	Alkyl hydroperoxide reductase
TES1_0612	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
TES1_0613	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
TES1_0615	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
TES1_0619	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
TES1_0622	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
TES1_0628	ENOG4105CJ1	ABC, transporter
TES1_0631	ENOG4105F8V	Hydrolase, tatD family
TES1_0633	ENOG4107VMB	Beta-lactamase domain protein
TES1_0634	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
TES1_0638	ENOG4107QRT	dEAD DEAH box helicase
TES1_0640	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
TES1_0643	ENOG4105E0A	ABC, transporter
TES1_0644	ENOG4105EHG	Permease protein
TES1_0657	ENOG4105DQU	oxidoreductase, subunit beta
TES1_0658	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
TES1_0660	ENOG4105DQU	oxidoreductase, subunit beta
TES1_0661	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
TES1_0665	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
TES1_0666	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
TES1_0670	ENOG41065SU	Two-component system sensor kinase
TES1_0675	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
TES1_0679	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
TES1_0684	ENOG4105CK7	Sodium proline symporter
TES1_0685	ENOG4105DT1	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate
TES1_0686	ENOG4107104	thymidine kinase
TES1_0692	ENOG4105D1Z	hydroxypyruvate reductase
TES1_0696	ENOG4106ETB	IIa component
TES1_0697	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
TES1_0698	ENOG4106ETB	IIa component
TES1_0699	ENOG4105KRI	phosphocarrier protein (HPr
TES1_0700	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
TES1_0701	ENOG4108SU4	UPF0309 protein
TES1_0702	ENOG4105CE4	GlcNAc 6-P deacetylase
TES1_0707	ENOG4105K4P	CoA-binding domain protein
TES1_0713	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
TES1_0715	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
TES1_0716	ENOG4105C5X	domain protein
TES1_0717	ENOG4108R96	Methyltransferase, YaeB family
TES1_0720	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
TES1_0723	ENOG4105WE2	aldehyde ferredoxin oxidoreductase
TES1_0734	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
TES1_0735	ENOG4105F73	Catalyzes the deformylation of 4-deoxy-4-formamido-L- arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
TES1_0736	ENOG4107UU3	sucrose-phosphate synthase (EC 2.4.1.14)
TES1_0744	ENOG4108VCT	Sulfite exporter TauE/SafE
TES1_0746	ENOG4105CD5	CoA-binding domain protein
TES1_0751	ENOG4106K5Q	Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication (By similarity)
TES1_0756	ENOG4108VA3	3-hexulose-6-phosphate synthase
TES1_0758	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
TES1_0763	ENOG4105C5S	asparaginyl-tRNA synthetase
TES1_0766	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
TES1_0767	ENOG410667J	hydrolase
TES1_0768	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
TES1_0769	ENOG4108Z0R	Transferase
TES1_0773	ENOG4105CN9	Peptidase m42 family protein
TES1_0777	ENOG4108JJB	ABC transporter
TES1_0778	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
TES1_0779	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
TES1_0780	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
TES1_0781	ENOG4105CJW	magnesium transporter
TES1_0783	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
TES1_0784	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
TES1_0787	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
TES1_0792	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
TES1_0814	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
TES1_0815	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
TES1_0816	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
TES1_0822	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
TES1_0825	ENOG4105CN9	Peptidase m42 family protein
TES1_0826	ENOG4105C5I	Dehydrogenase
TES1_0827	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
TES1_0829	ENOG4105CHM	Aminotransferase
TES1_0832	ENOG4105F4P	)-transporter
TES1_0834	ENOG4105EPU	Molybdenum cofactor synthesis domain protein
TES1_0835	ENOG4108D32	Methyltransferase
TES1_0837	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
TES1_0841	ENOG4105MRR	Transcriptional regulator (By similarity)
TES1_0843	ENOG4105CHR	reductase
TES1_0844	ENOG4108V1U	phospholipid-binding protein
TES1_0850	ENOG4107RWR	Sodium hydrogen exchanger
TES1_0852	ENOG4107RIU	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins (By similarity)
TES1_0856	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
TES1_0859	ENOG4105D9Y	Splits dipeptides with a prolyl residue in the C- terminal position (By similarity)
TES1_0860	ENOG4105EKT	)-iron permease
TES1_0866	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
TES1_0867	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
TES1_0868	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
TES1_0869	ENOG4108IZQ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
TES1_0870	ENOG4108JPZ	Monovalent cation H antiporter subunit D
TES1_0871	ENOG4108JPZ	Monovalent cation H antiporter subunit D
TES1_0873	ENOG4105D65	subunit l
TES1_0875	ENOG4105KJM	monovalent cation h antiporter subunit g
TES1_0876	ENOG410684G	monovalent cation H antiporter subunit F
TES1_0877	ENOG4105SC1	monovalent cation H antiporter subunit E
TES1_0879	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
TES1_0881	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
TES1_0882	ENOG4108IJ1	Dehydrogenase
TES1_0887	ENOG4105C75	arginyL-tRNA synthetase
TES1_0889	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
TES1_0901	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
TES1_0905	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
TES1_0907	ENOG4105C22	threonyL-tRNA synthetase
TES1_0913	ENOG4105D07	Signal peptide peptidase, SppA
TES1_0915	ENOG4105F4G	Membrane
TES1_0917	ENOG4105FDK	ABC transporter
TES1_0918	ENOG4108I5C	dEAD DEAH box helicase
TES1_0923	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
TES1_0924	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
TES1_0925	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
TES1_0926	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
TES1_0928	ENOG4105CIH	Imidazole acetol-phosphate transaminase
TES1_0937	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
TES1_0938	ENOG4105C98	muts2 protein
TES1_0939	ENOG4105G0J	serine threonine protein kinase
TES1_0941	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
TES1_0945	ENOG4105DCI	Phosphohydrolase
TES1_0953	ENOG4105D0M	Protease HtpX homolog
TES1_0954	ENOG4107RB4	Cytidine monophosphate kinase
TES1_0956	ENOG4105DZH	s-adenosylmethionine synthetase (EC 2.5.1.6)
TES1_0958	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
TES1_0962	ENOG4105C1A	potassium transporter peripheral membrane
TES1_0967	ENOG4108K7V	UPF0284 protein
TES1_0968	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
TES1_0970	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
TES1_0971	ENOG4105GSQ	TM1410 hypothetical-related protein
TES1_0973	ENOG4108UHF	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
TES1_0978	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
TES1_0980	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
TES1_0983	ENOG4105CIH	Imidazole acetol-phosphate transaminase
TES1_0984	ENOG4108393	oxidoreductase Fe-S subunit
TES1_0985	ENOG4105BZ8	glutamate synthase
TES1_0989	ENOG4107QRT	dEAD DEAH box helicase
TES1_0993	ENOG4105D5T	phosphonate abc transporter
TES1_0996	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
TES1_0997	ENOG4105C8N	cysteinyl-tRNA synthetase
TES1_0999	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
TES1_1003	ENOG4105DSE	periplasmic solute binding protein
TES1_1005	ENOG4105UIB	(ABC) transporter
TES1_1006	ENOG4108JQ9	ABC transporter
TES1_1007	ENOG4105DIH	basic membrane
TES1_1009	ENOG4105ZHF	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
TES1_1010	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
TES1_1015	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
TES1_1022	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
TES1_1027	ENOG4105DK7	lysyl-tRNA synthetase
TES1_1030	ENOG4105D44	asparaginase
TES1_1031	ENOG4105C6X	Major Facilitator
TES1_1035	ENOG4105DJB	Major Facilitator Superfamily
TES1_1036	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
TES1_1038	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
TES1_1041	ENOG4108UK2	deaminase
TES1_1042	ENOG4105D0M	Protease HtpX homolog
TES1_1044	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
TES1_1047	ENOG4108UMS	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase (By similarity)
TES1_1049	ENOG4105CJP	fad dependent oxidoreductase
TES1_1055	ENOG4105CIF	Ornithine Cyclodeaminase
TES1_1056	ENOG4105CTU	Proline racemase
TES1_1057	ENOG4105C8J	)-transporter
TES1_1058	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
TES1_1059	ENOG4108UMR	transcriptional regulator AsnC family
TES1_1060	ENOG4107R7Y	intracellular protease Pfpi family
TES1_1065	ENOG4108UKZ	OsmC family
TES1_1067	ENOG4108Z86	Glutamine amidotransferase
TES1_1069	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
TES1_1072	ENOG4107R0K	CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity)
TES1_1074	ENOG4105C2X	Arabinose 5-phosphate isomerase
TES1_1077	ENOG4105C83	adenylosuccinate lyase
TES1_1078	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
TES1_1080	ENOG4105D1F	ATP-binding protein
TES1_1083	ENOG4105VYW	UPF0251 protein
TES1_1091	ENOG4105C1J	atp-dependent rna helicase
TES1_1095	ENOG4108RCS	geranylgeranylglyceryl phosphate synthase
TES1_1098	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
TES1_1100	ENOG4107QX8	SPFH domain, Band 7 family protein
TES1_1108	ENOG4105EW9	transcriptional regulator AsnC family
TES1_1110	ENOG4105E7W	lamb ycsf family protein
TES1_1111	ENOG4105P4J	Allophanate hydrolase, subunit 1
TES1_1114	ENOG4108MDK	Dehydrogenase
TES1_1118	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
TES1_1119	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
TES1_1123	ENOG4105D5P	Methylmalonyl-coA mutase
TES1_1124	ENOG4105DCG	PHP domain protein
TES1_1125	ENOG4108Z03	MAF-like protein
TES1_1129	ENOG4105CAQ	asparagine synthetase
TES1_1131	ENOG4105CPK	Glycosyl transferase (Group 1
TES1_1132	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
TES1_1135	ENOG4106IPI	cyclase, family
TES1_1136	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
TES1_1140	ENOG4105E8V	Alpha Beta Hydrolase Fold protein
TES1_1142	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
TES1_1145	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
TES1_1160	ENOG4105CD5	CoA-binding domain protein
TES1_1163	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
TES1_1165	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
TES1_1166	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
TES1_1173	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
TES1_1174	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
TES1_1176	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
TES1_1177	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
TES1_1178	ENOG4105C5I	Dehydrogenase
TES1_1181	ENOG4108Y5D	Inherit from COG: cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
TES1_1193	ENOG4105DVT	helicase
TES1_1195	ENOG4105CN9	Peptidase m42 family protein
TES1_1197	ENOG4108JPZ	Monovalent cation H antiporter subunit D
TES1_1199	ENOG4105MKQ	Monovalent cation H antiporter subunit C
TES1_1200	ENOG4108PMQ	Na H antiporter MnhB subunit-related protein
TES1_1202	ENOG4105KJM	monovalent cation h antiporter subunit g
TES1_1204	ENOG4105C47	NADH ubiquinone oxidoreductase 20 kda subunit
TES1_1206	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
TES1_1207	ENOG4107TDF	Formate hydrogenlyase subunit 4
TES1_1208	ENOG4108JPZ	Monovalent cation H antiporter subunit D
TES1_1210	ENOG4105D0U	Arsenite-activated ATPase (ArsA)
TES1_1211	ENOG4105CJG	carbon-monoxide dehydrogenase catalytic subunit
TES1_1212	ENOG4105QAX	Iron-sulfur
TES1_1215	ENOG4105PW4	Sugar fermentation stimulation protein homolog
TES1_1217	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
TES1_1220	ENOG4108TVJ	Nitroreductase
TES1_1222	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
TES1_1223	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
TES1_1230	ENOG4105CD5	CoA-binding domain protein
TES1_1234	ENOG4105CSM	endonuclease III
TES1_1237	ENOG4105CJ1	ABC, transporter
TES1_1240	ENOG4105BZA	Phosphoglycerate kinase
TES1_1244	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
TES1_1245	ENOG4107RCV	ABC transporter, permease
TES1_1249	ENOG4105C1J	atp-dependent rna helicase
TES1_1251	ENOG4105C5S	asparaginyl-tRNA synthetase
TES1_1252	ENOG41080U2	Amidohydrolase family
TES1_1256	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
TES1_1275	ENOG4105VEV	-acetyltransferase
TES1_1280	ENOG4105DXX	methyltransferase
TES1_1285	ENOG4107UX3	phosphatidylethanolamine N-methyltransferase
TES1_1295	ENOG4107SA6	carbon-phosphorus lyase complex accessory protein
TES1_1303	ENOG4107XMU	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
TES1_1304	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
TES1_1305	ENOG4107Y70	Heat shock protein
TES1_1307	ENOG4108JPW	Aminotransferase
TES1_1311	ENOG4105CHM	Aminotransferase
TES1_1314	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
TES1_1315	ENOG4107QJE	Chromosome Partitioning Protein
TES1_1317	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
TES1_1320	ENOG4105D5P	Methylmalonyl-coA mutase
TES1_1321	ENOG4107T0X	DNA ligase
TES1_1327	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
TES1_1328	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
TES1_1333	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
TES1_1334	ENOG4105CHU	acetyl-coa acetyltransferase
TES1_1346	ENOG4107WCI	zn-dependent hydrolase of the beta-lactamase fold-like protein
TES1_1350	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
TES1_1351	ENOG4105WE2	aldehyde ferredoxin oxidoreductase
TES1_1354	ENOG41084T3	4fe-4S ferredoxin iron-sulfur binding domain-containing protein
TES1_1355	ENOG41084T3	4fe-4S ferredoxin iron-sulfur binding domain-containing protein
TES1_1356	ENOG4105VG1	fes assembly suf system protein
TES1_1360	ENOG4107W9I	Creatinine amidohydrolase
TES1_1361	ENOG4105E2K	Glycosyl transferase (Group 1
TES1_1365	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
TES1_1366	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
TES1_1375	ENOG4105KJM	monovalent cation h antiporter subunit g
TES1_1376	ENOG41080TA	Multiple resistance and ph regulation protein f
TES1_1377	ENOG4105SC1	monovalent cation H antiporter subunit E
TES1_1379	ENOG4105C45	hydrogenase expression formation protein (HypE)
TES1_1380	ENOG41080XS	Cobyrinic acid ac-diamide synthase
TES1_1386	ENOG4108JVH	Protein of unknown function DUF43
TES1_1390	ENOG4105SZ6	Thioredoxin
TES1_1394	ENOG4107UX3	phosphatidylethanolamine N-methyltransferase
TES1_1396	ENOG4105C28	cystathionine
TES1_1408	ENOG4105C3K	feS assembly ATPase SufC
TES1_1409	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
TES1_1410	ENOG4105D06	uba thif-type nad fad binding protein
TES1_1411	ENOG41090A1	ferritin
TES1_1414	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
TES1_1416	ENOG4107ZCS	Phosphomethylpyrimidine kinase
TES1_1420	ENOG4105C9B	Cysteine desulfurase
TES1_1426	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
TES1_1428	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
TES1_1438	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
TES1_1439	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
TES1_1443	ENOG4107R3E	Citrate transporter
TES1_1451	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
TES1_1452	ENOG4107TDF	Formate hydrogenlyase subunit 4
TES1_1453	ENOG4108HM5	NADH-ubiquinone oxidoreductase chain 49kDa
TES1_1454	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
TES1_1455	ENOG4105C47	NADH ubiquinone oxidoreductase 20 kda subunit
TES1_1457	ENOG4108JPZ	Monovalent cation H antiporter subunit D
TES1_1458	ENOG4105MKQ	Monovalent cation H antiporter subunit C
TES1_1462	ENOG4105KJM	monovalent cation h antiporter subunit g
TES1_1463	ENOG41080TA	Multiple resistance and ph regulation protein f
TES1_1466	ENOG4107TDF	Formate hydrogenlyase subunit 4
TES1_1467	ENOG4108HM5	NADH-ubiquinone oxidoreductase chain 49kDa
TES1_1468	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
TES1_1469	ENOG4105C47	NADH ubiquinone oxidoreductase 20 kda subunit
TES1_1471	ENOG4108JPZ	Monovalent cation H antiporter subunit D
TES1_1472	ENOG4108ZE9	Monovalent cation H antiporter subunit C
TES1_1476	ENOG4105KJM	monovalent cation h antiporter subunit g
TES1_1478	ENOG4105SC1	monovalent cation H antiporter subunit E
TES1_1479	ENOG4108JPZ	Monovalent cation H antiporter subunit D
TES1_1481	ENOG4105MKQ	Monovalent cation H antiporter subunit C
TES1_1482	ENOG4108PMQ	Na H antiporter MnhB subunit-related protein
TES1_1484	ENOG4105KJM	monovalent cation h antiporter subunit g
TES1_1486	ENOG4105TMB	Formate nitrite transporter
TES1_1488	ENOG4105C47	NADH ubiquinone oxidoreductase 20 kda subunit
TES1_1489	ENOG4108RG7	formate hydrogenlyase complex iron-sulfur subunit
TES1_1490	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
TES1_1491	ENOG4107TDF	Formate hydrogenlyase subunit 4
TES1_1492	ENOG4108JPZ	Monovalent cation H antiporter subunit D
TES1_1493	ENOG4108JPZ	Monovalent cation H antiporter subunit D
TES1_1494	ENOG4105D65	subunit l
TES1_1495	ENOG4108393	oxidoreductase Fe-S subunit
TES1_1496	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
TES1_1497	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
TES1_1500	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
TES1_1502	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
TES1_1503	ENOG4105EHU	Circadian clock protein KaiC
TES1_1504	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
TES1_1507	ENOG4105VZ8	Transcriptional regulator
TES1_1508	ENOG4105CJ1	ABC, transporter
TES1_1513	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
TES1_1519	ENOG4105CDJ	oxidoreductase FAD NAD(P)-binding domain protein
TES1_1520	ENOG4105BZ8	glutamate synthase
TES1_1522	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
TES1_1525	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
TES1_1527	ENOG4108UUC	Protein of unknown function DUF99
TES1_1528	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
TES1_1531	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
TES1_1533	ENOG4105C3M	thioredoxin reductase
TES1_1534	ENOG4108JPW	Aminotransferase
TES1_1536	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
TES1_1539	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
TES1_1540	ENOG4108RVA	ribokinase
TES1_1543	ENOG4105CJ1	ABC, transporter
TES1_1548	ENOG4105D1F	ATP-binding protein
TES1_1549	ENOG4105DDK	oxidoreductase, beta subunit
TES1_1550	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
TES1_1552	ENOG4105DDK	oxidoreductase, beta subunit
TES1_1553	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
TES1_1554	ENOG4105WGB	oxidoreductase, delta subunit
TES1_1556	ENOG4107QXV	Phosphate transporter
TES1_1557	ENOG4105CJ3	phosphate transporter
TES1_1558	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
TES1_1560	ENOG4107RWR	Sodium hydrogen exchanger
TES1_1564	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
TES1_1566	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
TES1_1568	ENOG4108JQ1	Dehydrogenase
TES1_1570	ENOG4107GFK	fumarate
TES1_1575	ENOG4107YZX	Universal stress protein
TES1_1576	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
TES1_1578	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
TES1_1579	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
TES1_1596	ENOG4105EB1	binding-protein-dependent transport systems inner membrane Component
TES1_1597	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
TES1_1603	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
TES1_1604	ENOG4108JQ7	(ABC) transporter
TES1_1606	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
TES1_1607	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
TES1_1608	ENOG4105DEF	Extracellular solute-binding protein, family 5
TES1_1612	ENOG4105C6K	Malic enzyme
TES1_1613	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
TES1_1618	ENOG4105C7N	Xanthine uracil vitamin C permease
TES1_1621	ENOG4108S8N	class II Aldolase
TES1_1623	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
TES1_1630	ENOG4105NBF	ammecr1 domain protein
TES1_1631	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
TES1_1632	ENOG4105CQ2	DNA polymerase
TES1_1643	ENOG4105VUN	Transcriptional regulator
TES1_1644	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
TES1_1647	ENOG4108RWI	nicotinamidase
TES1_1654	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
TES1_1656	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
TES1_1657	ENOG4108NGU	Transcriptional regulator
TES1_1659	ENOG4107FKK	extracellular solute-binding protein family 1
TES1_1661	ENOG4105EG2	ABC transporter, permease
TES1_1665	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
TES1_1666	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
TES1_1667	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
TES1_1668	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
TES1_1669	ENOG4105DR4	Methyltransferase
TES1_1674	ENOG4105EHU	Circadian clock protein KaiC
TES1_1682	ENOG4105C5F	glutamine synthetase
TES1_1684	ENOG4105C4K	Nad synthetase
TES1_1686	ENOG4108JQ7	(ABC) transporter
TES1_1687	ENOG4105C3U	ABC transporter
TES1_1688	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
TES1_1694	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
TES1_1695	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
TES1_1696	ENOG4105M56	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
TES1_1698	ENOG4108JIQ	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit (By similarity)
TES1_1701	ENOG4105K4G	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
TES1_1705	ENOG4105C1A	potassium transporter peripheral membrane
TES1_1706	ENOG4105C3D	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
TES1_1707	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
TES1_1708	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
TES1_1710	ENOG4105EHU	Circadian clock protein KaiC
TES1_1715	ENOG4107XF7	NGG1p interacting factor 3 protein, NIF3
TES1_1717	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
TES1_1718	ENOG4105BZG	amino acid carrier protein
TES1_1719	ENOG4108JPW	Aminotransferase
TES1_1721	ENOG4105CUT	histidyl-tRNA synthetase
TES1_1723	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
TES1_1734	ENOG4105IIU	Aminopeptidase
TES1_1735	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
TES1_1738	ENOG4105DP9	ABC transporter
TES1_1742	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
TES1_1743	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
TES1_1744	ENOG4105ESI	atpase involved in dna repair
TES1_1749	ENOG4108MYP	Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four- carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
TES1_1751	ENOG4105VKD	bioY protein
TES1_1752	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
TES1_1754	ENOG4108JJB	ABC transporter
TES1_1755	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
TES1_1759	ENOG4108I5C	dEAD DEAH box helicase
TES1_1760	ENOG4105EW9	transcriptional regulator AsnC family
TES1_1761	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
TES1_1765	ENOG4107QXV	Phosphate transporter
TES1_1770	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
TES1_1772	ENOG4108IGT	Dipeptidase
TES1_1774	ENOG4105VFR	signal peptidase
TES1_1775	ENOG4107S5Z	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity)
TES1_1784	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
TES1_1791	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
TES1_1793	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
TES1_1795	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
TES1_1804	ENOG4105D06	uba thif-type nad fad binding protein
TES1_1806	ENOG4105D0M	Protease HtpX homolog
TES1_1811	ENOG4108ZAF	Molybdopterin
TES1_1815	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
TES1_1816	ENOG4108VVK	transcriptional Regulator, AsnC
TES1_1818	ENOG4107NFR	Fructose-1,6-bisphosphatase
TES1_1828	ENOG4106J7S	Glycosyl transferase, family 2
TES1_1835	ENOG4105CYV	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures (By similarity)
TES1_1838	ENOG4105CB1	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
TES1_1839	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
TES1_1840	ENOG4105D1H	recombination factor protein RarA
TES1_1841	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
TES1_1844	ENOG41082SX	arsR family transcriptional regulator
TES1_1845	ENOG4107QWE	)-transporter
TES1_1849	ENOG4105ERH	Fumarylacetoacetate hydrolase
TES1_1851	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
TES1_1852	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
TES1_1859	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
TES1_1864	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
TES1_1868	ENOG4105CTD	carboxy-peptidase
TES1_1872	ENOG4108KN7	Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity)
TES1_1876	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
TES1_1884	ENOG4105J5G	Transferase hexapeptide repeat containing protein
TES1_1886	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
TES1_1887	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
TES1_1889	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
TES1_1893	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
TES1_1899	ENOG4105C6W	4-alpha-glucanotransferase (EC 2.4.1.25)
TES1_1901	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
TES1_1903	ENOG4105DZ0	fad dependent oxidoreductase
TES1_1905	ENOG4107RWR	Sodium hydrogen exchanger
TES1_1906	ENOG4107RWR	Sodium hydrogen exchanger
TES1_1907	ENOG4108VVK	transcriptional Regulator, AsnC
TES1_1908	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
TES1_1910	ENOG4107RYT	DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair (By similarity)
TES1_1913	ENOG4105CEC	DNA methylase N-4 N-6
TES1_1914	ENOG4107S6Z	Na H antiporter
TES1_1915	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
TES1_1917	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
TES1_1921	ENOG4105D7K	pfkb domain protein
TES1_1924	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
TES1_1925	ENOG4105HS6	binding-protein-dependent transport systems inner membrane Component
TES1_1927	ENOG41088YS	Glycosyl transferase (Group 1
TES1_1930	ENOG4105VAW	lrga family
TES1_1931	ENOG41067MG	lrgb family
TES1_1954	ENOG410825M	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
TES1_1955	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
TES1_1959	ENOG4105EM7	Selenocysteine-specific translation elongation factor
TES1_1961	ENOG4105F0N	pyrophosphate phospho-hydrolase
TES1_1962	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
TES1_1967	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
TES1_1968	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
TES1_1980	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
TES1_1981	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
TES1_1982	ENOG4105IQJ	Involved in biosynthesis of the thiamine precursor thiazole (By similarity)
TES1_1984	ENOG4105C8V	SAICAR synthetase
TES1_1987	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
TES1_1988	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
TES1_1989	ENOG4108R6K	riboflavin synthase, subunit alpha
TES1_1990	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
TES1_1991	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
TES1_1996	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
TES1_1998	ENOG4105G6Z	alkaline phosphatase
TES1_2007	ENOG4107RIQ	Sulfate adenylate transferase
TES1_2012	ENOG4107T1U	Catalyzes the synthesis of activated sulfate (By similarity)
TES1_2013	ENOG4107TSN	permease
TES1_2020	ENOG4105CNB	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
TES1_2026	ENOG4107V9E	glucose-1-phosphate thymidylyltransferase
TES1_2028	ENOG4105E0M	Sulfatase
TES1_2030	ENOG4107XB0	Lipopolysaccharide 1,2-N-acetylglucosaminetransferase
TES1_2032	ENOG4105CPK	Glycosyl transferase (Group 1
TES1_2034	ENOG4107RA4	Glycosyl transferase (Group 1
TES1_2036	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
TES1_2040	ENOG4105J5G	Transferase hexapeptide repeat containing protein