locus-tag	class	description
A0127_00010	ENOG4108JJB	ABC transporter
A0127_00030	ENOG4108RCS	geranylgeranylglyceryl phosphate synthase
A0127_00045	ENOG4105C1J	atp-dependent rna helicase
A0127_00065	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
A0127_00075	ENOG4107QRT	dEAD DEAH box helicase
A0127_00105	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
A0127_00125	ENOG4105E5G	Alpha beta hydrolase fold
A0127_00145	ENOG4105VG1	fes assembly suf system protein
A0127_00150	ENOG4105D0U	Arsenite-activated ATPase (ArsA)
A0127_00165	ENOG4105D22	carbon starvation protein
A0127_00170	ENOG4107QSA	Oxaloacetate decarboxylase
A0127_00175	ENOG41061GT	Aldolase
A0127_00180	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
A0127_00185	ENOG4105CK2	sodium dicarboxylate symporter
A0127_00195	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
A0127_00215	ENOG4105ZHF	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
A0127_00220	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
A0127_00245	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
A0127_00255	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
A0127_00275	ENOG4105UQX	Mate efflux family protein
A0127_00295	ENOG4108K3F	N(2),N(2)-dimethylguanosine tRNA methyltransferase
A0127_00310	ENOG4105DC7	peptidase M24
A0127_00350	ENOG4105CE1	Ferrous iron transport protein b
A0127_00365	ENOG4108Z03	MAF-like protein
A0127_00375	ENOG4105CTP	PilT protein domain protein
A0127_00390	ENOG4105CAQ	asparagine synthetase
A0127_00400	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
A0127_00445	ENOG4105CD5	CoA-binding domain protein
A0127_00490	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
A0127_00495	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
A0127_00500	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
A0127_00520	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
A0127_00525	ENOG4105CPQ	Dehydrogenase
A0127_00550	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
A0127_00555	ENOG4105HDK	L-asparaginase
A0127_00565	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
A0127_00595	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
A0127_00605	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
A0127_00635	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
A0127_00640	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
A0127_00650	ENOG4105CMQ	Chloride channel
A0127_00660	ENOG4107RWR	Sodium hydrogen exchanger
A0127_00680	ENOG4107R3E	Citrate transporter
A0127_00730	ENOG4105DBV	ornithine carbamoyltransferase
A0127_00740	ENOG4108V3W	Chemotaxis protein, CheW
A0127_00745	ENOG4108N3W	hemolysin secretion protein
A0127_00750	ENOG4105BZU	Histidine kinase
A0127_00755	ENOG4107YTP	response regulator receiver protein
A0127_00760	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
A0127_00765	ENOG4105CBS	Chea signal transduction histidine kinase
A0127_00780	ENOG4105C8Q	Methyl-accepting chemotaxis
A0127_00785	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
A0127_00800	ENOG41087GE	Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity)
A0127_00820	ENOG4105E3H	phosphoglycerate mutase
A0127_00825	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
A0127_00830	ENOG4105CPC	Aldo Keto reductase
A0127_00870	ENOG4105EMU	Dehydrogenase
A0127_00875	ENOG4105F4P	)-transporter
A0127_00915	ENOG4105C3K	feS assembly ATPase SufC
A0127_00920	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
A0127_00925	ENOG4105D06	uba thif-type nad fad binding protein
A0127_00930	ENOG4107Y03	Nitroreductase
A0127_00960	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
A0127_00970	ENOG4108EQM	faD-dependent pyridine nucleotide-disulfide oxidoreductase
A0127_01000	ENOG4105DQU	oxidoreductase, subunit beta
A0127_01005	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
A0127_01020	ENOG4108ESE	uses NADH to detoxify nitric oxide (NO), protecting several 4Fe-4S NO-sensitive enzymes. Has at least 2 reductase partners, only one of which (NorW, flavorubredoxin reductase) has been identified. NO probably binds to the di-iron center
A0127_01030	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
A0127_01045	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
A0127_01065	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
A0127_01075	ENOG4105FDK	ABC transporter
A0127_01095	ENOG41065SU	Two-component system sensor kinase
A0127_01115	ENOG4105FBQ	ATPase associated with various cellular activities aaa_5
A0127_01125	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
A0127_01135	ENOG4108I6A	alcohol dehydrogenase
A0127_01145	ENOG4105ECY	inositol monophosphatase
A0127_01150	ENOG4107ZXI	Rhomboid family
A0127_01165	ENOG4105DVT	helicase
A0127_01180	ENOG4105CN9	Peptidase m42 family protein
A0127_01195	ENOG4105PW4	Sugar fermentation stimulation protein homolog
A0127_01205	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
A0127_01215	ENOG4105DER	m42 family
A0127_01225	ENOG4105EYF	MMPL domain protein
A0127_01240	ENOG4105VZ9	UPF0235 protein
A0127_01250	ENOG4107QRT	dEAD DEAH box helicase
A0127_01260	ENOG4107QJZ	Glycosyl transferase, family 2
A0127_01270	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
A0127_01285	ENOG4105C5S	asparaginyl-tRNA synthetase
A0127_01290	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
A0127_01295	ENOG4105DP9	ABC transporter
A0127_01310	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
A0127_01315	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
A0127_01340	ENOG4105VKD	bioY protein
A0127_01345	ENOG4108JJB	ABC transporter
A0127_01350	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
A0127_01380	ENOG4105CHR	reductase
A0127_01385	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
A0127_01395	ENOG4105C3K	feS assembly ATPase SufC
A0127_01405	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
A0127_01460	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
A0127_01465	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
A0127_01475	ENOG4105D1F	ATP-binding protein
A0127_01485	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
A0127_01500	ENOG41079KZ	Major Facilitator Superfamily
A0127_01505	ENOG4108J2R	molybdopterin oxidoreductase
A0127_01535	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
A0127_01545	ENOG4105C5I	Dehydrogenase
A0127_01550	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
A0127_01560	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
A0127_01565	ENOG4105D0M	Protease HtpX homolog
A0127_01570	ENOG4105CHR	reductase
A0127_01575	ENOG4105BZ8	glutamate synthase
A0127_01585	ENOG4105E0R	Deoxyhypusine synthase
A0127_01595	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
A0127_01610	ENOG4105CD5	CoA-binding domain protein
A0127_01615	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
A0127_01640	ENOG4105UIB	(ABC) transporter
A0127_01645	ENOG4108JQ9	ABC transporter
A0127_01650	ENOG4105DIH	basic membrane
A0127_01660	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
A0127_01700	ENOG4108YZ8	Superoxide reductase
A0127_01705	ENOG4105VCQ	rubredoxin
A0127_01710	ENOG4108RAC	Rubrerythrin
A0127_01715	ENOG4108I5C	dEAD DEAH box helicase
A0127_01720	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
A0127_01730	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
A0127_01740	ENOG4105KJJ	Uncharacterized ACR, COG1993
A0127_01745	ENOG4105WMR	Protein CrcB homolog
A0127_01785	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
A0127_01790	ENOG4108VVK	transcriptional Regulator, AsnC
A0127_01800	ENOG4105C3G	gtp-binding protein
A0127_01805	ENOG4105D7N	magnesium and cobalt transport protein CorA
A0127_01810	ENOG4105CG9	aspartate racemase
A0127_01850	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
A0127_01855	ENOG4105ECW	sulfate abc transporter
A0127_01900	ENOG4105VYW	UPF0251 protein
A0127_01905	ENOG4105C83	adenylosuccinate lyase
A0127_01920	ENOG41080XQ	Signal transduction protein with cbs domains
A0127_01930	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
A0127_01945	ENOG4105CN9	Peptidase m42 family protein
A0127_01950	ENOG4105C5I	Dehydrogenase
A0127_01955	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
A0127_01965	ENOG4105CHM	Aminotransferase
A0127_01980	ENOG4105DZH	s-adenosylmethionine synthetase (EC 2.5.1.6)
A0127_01985	ENOG4105GSQ	TM1410 hypothetical-related protein
A0127_02005	ENOG4108K7V	UPF0284 protein
A0127_02015	ENOG4105EPU	Molybdenum cofactor synthesis domain protein
A0127_02020	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
A0127_02030	ENOG4105DCI	Phosphohydrolase
A0127_02045	ENOG4105D3R	alkyl hydroperoxide reductase
A0127_02075	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
A0127_02090	ENOG4105SFS	phosphoesterase RecJ domain protein
A0127_02120	ENOG4105C8S	subunit m
A0127_02145	ENOG4105KJM	monovalent cation h antiporter subunit g
A0127_02150	ENOG4105W4C	monovalent cation H antiporter subunit F
A0127_02155	ENOG4105SC1	monovalent cation H antiporter subunit E
A0127_02190	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
A0127_02195	ENOG4105UQX	Mate efflux family protein
A0127_02215	ENOG4108R6K	riboflavin synthase, subunit alpha
A0127_02220	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
A0127_02235	ENOG4108IA2	Sodium pantothenate symporter
A0127_02250	ENOG4105C8V	SAICAR synthetase
A0127_02260	ENOG4105IQJ	Involved in biosynthesis of the thiamine precursor thiazole (By similarity)
A0127_02265	ENOG4105DWF	phosphomethylpyrimidine kinase
A0127_02275	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
A0127_02295	ENOG4105C8N	cysteinyl-tRNA synthetase
A0127_02305	ENOG4105CD5	CoA-binding domain protein
A0127_02325	ENOG4106K5Q	Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication (By similarity)
A0127_02345	ENOG4105CYW	agmatinase
A0127_02350	ENOG4108VA3	3-hexulose-6-phosphate synthase
A0127_02360	ENOG4107XGZ	Hydrolase
A0127_02385	ENOG4105C5S	asparaginyl-tRNA synthetase
A0127_02395	ENOG4105CH2	amidohydrolase
A0127_02450	ENOG4108DBC	nitroreductase
A0127_02460	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
A0127_02470	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
A0127_02485	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
A0127_02525	ENOG4108T0W	nitrous oxide maturation protein NosY
A0127_02540	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
A0127_02550	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
A0127_02565	ENOG4107QMS	site-determining protein
A0127_02570	ENOG4107QX8	SPFH domain, Band 7 family protein
A0127_02605	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
A0127_02610	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
A0127_02620	ENOG4105E7W	lamb ycsf family protein
A0127_02625	ENOG4105P4J	Allophanate hydrolase, subunit 1
A0127_02650	ENOG4105D5P	Methylmalonyl-coA mutase
A0127_02670	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
A0127_02680	ENOG4105F8V	Hydrolase, tatD family
A0127_02695	ENOG4105C5X	domain protein
A0127_02700	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
A0127_02705	ENOG4105DCI	Phosphohydrolase
A0127_02710	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
A0127_02720	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
A0127_02730	ENOG4105C1J	atp-dependent rna helicase
A0127_02750	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
A0127_02765	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
A0127_02795	ENOG4108IYU	L-aspartate oxidase
A0127_02805	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
A0127_02825	ENOG4107SA6	carbon-phosphorus lyase complex accessory protein
A0127_02830	ENOG4108TVJ	Nitroreductase
A0127_02840	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
A0127_02925	ENOG4105CNB	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
A0127_02930	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
A0127_02935	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
A0127_02940	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
A0127_02945	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
A0127_02955	ENOG4105C8V	SAICAR synthetase
A0127_02965	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
A0127_02985	ENOG4107QNG	Phosphoribosylglycinamide synthetase
A0127_03000	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
A0127_03010	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
A0127_03025	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
A0127_03030	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
A0127_03035	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
A0127_03040	ENOG4108UKZ	OsmC family
A0127_03055	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
A0127_03060	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
A0127_03085	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
A0127_03090	ENOG4105CHU	acetyl-coa acetyltransferase
A0127_03115	ENOG4105NBF	ammecr1 domain protein
A0127_03160	ENOG4105E0C	molybdate abc transporter
A0127_03165	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
A0127_03170	ENOG4105C7N	Xanthine uracil vitamin C permease
A0127_03180	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
A0127_03205	ENOG4107R7Y	intracellular protease Pfpi family
A0127_03215	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
A0127_03230	ENOG4107R5H	iron (metal) dependent repressor, dtxr family
A0127_03245	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
A0127_03270	ENOG4105CK7	Sodium proline symporter
A0127_03315	ENOG41080E2	ribosomal-protein-alanine acetyltransferase
A0127_03375	ENOG4107WCI	zn-dependent hydrolase of the beta-lactamase fold-like protein
A0127_03405	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
A0127_03420	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
A0127_03435	ENOG4105BZ8	glutamate synthase
A0127_03440	ENOG4105CDJ	oxidoreductase FAD NAD(P)-binding domain protein
A0127_03470	ENOG4105DEF	Extracellular solute-binding protein, family 5
A0127_03475	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
A0127_03480	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
A0127_03490	ENOG4108JQ7	(ABC) transporter
A0127_03520	ENOG4105CJ1	ABC, transporter
A0127_03530	ENOG4105VZ8	Transcriptional regulator
A0127_03550	ENOG4105WE2	aldehyde ferredoxin oxidoreductase
A0127_03555	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
A0127_03625	ENOG4105EAC	phosphoserine phosphatase
A0127_03630	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
A0127_03745	ENOG4107VWA	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation (By similarity)
A0127_03755	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
A0127_03760	ENOG4108R96	Methyltransferase, YaeB family
A0127_03765	ENOG4107XGZ	Hydrolase
A0127_03770	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
A0127_03775	ENOG4105E0C	molybdate abc transporter
A0127_03780	ENOG41066FR	extracellular solute-binding protein
A0127_03795	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
A0127_03820	ENOG4105K4P	CoA-binding domain protein
A0127_03835	ENOG4108VKG	metal-dependent hydrolase
A0127_03840	ENOG4105CQ2	DNA polymerase
A0127_03845	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
A0127_03855	ENOG4105CJ1	ABC, transporter
A0127_03865	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
A0127_03905	ENOG4108RMN	UPF0128 protein
A0127_03925	ENOG4105DT1	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate
A0127_03970	ENOG4108Y5D	Inherit from COG: cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
A0127_03985	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
A0127_03995	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
A0127_04005	ENOG4107QJE	Chromosome Partitioning Protein
A0127_04010	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
A0127_04025	ENOG4105CHM	Aminotransferase
A0127_04060	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
A0127_04065	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
A0127_04080	ENOG4105D0M	Protease HtpX homolog
A0127_04085	ENOG4108UK2	deaminase
A0127_04095	ENOG4107XGZ	Hydrolase
A0127_04100	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
A0127_04110	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
A0127_04115	ENOG4105DJB	Major Facilitator Superfamily
A0127_04130	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
A0127_04140	ENOG4105D44	asparaginase
A0127_04165	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
A0127_04170	ENOG4105DK7	lysyl-tRNA synthetase
A0127_04210	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
A0127_04225	ENOG4105E8R	UPF0173 metal-dependent hydrolase
A0127_04230	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
A0127_04245	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
A0127_04260	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
A0127_04265	ENOG4105C6E	dna polymerase iii
A0127_04275	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
A0127_04290	ENOG4108Z24	l-2,4-diaminobutyric acid acetyltransferase
A0127_04305	ENOG4107WZZ	SMC domain protein
A0127_04305	ENOG4107WZZ	SMC domain protein
A0127_04315	ENOG4105EHG	Permease protein
A0127_04325	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
A0127_04335	ENOG4105NBF	ammecr1 domain protein
A0127_04360	ENOG4105CXT	aspartate transcarbamylase
A0127_04365	ENOG4108R9M	Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity)
A0127_04385	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
A0127_04405	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
A0127_04455	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
A0127_04460	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
A0127_04475	ENOG4107PP3	Acetylornithine deacetylase
A0127_04490	ENOG4105EHU	Circadian clock protein KaiC
A0127_04500	ENOG4105IIU	Aminopeptidase
A0127_04600	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
A0127_04615	ENOG4105D64	Mechanosensitive ion channel
A0127_04645	ENOG4105EM7	Selenocysteine-specific translation elongation factor
A0127_04665	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
A0127_04670	ENOG410825M	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
A0127_04730	ENOG4107NFR	Fructose-1,6-bisphosphatase
A0127_04740	ENOG4105EWK	phytoene
A0127_04780	ENOG41067MG	lrgb family
A0127_04785	ENOG4105VAW	lrga family
A0127_04795	ENOG4105C8Q	Methyl-accepting chemotaxis
A0127_04805	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
A0127_04815	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
A0127_04820	ENOG4107S6Z	Na H antiporter
A0127_04840	ENOG4107SW0	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
A0127_04845	ENOG4107U53	septum site-determining protein minD
A0127_04855	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
A0127_04860	ENOG4108VVK	transcriptional Regulator, AsnC
A0127_04875	ENOG4108S8N	class II Aldolase
A0127_04885	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
A0127_04900	ENOG4108JQ1	Dehydrogenase
A0127_04910	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
A0127_04920	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
A0127_04965	ENOG4107RWR	Sodium hydrogen exchanger
A0127_04985	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
A0127_04990	ENOG4105CJ3	phosphate transporter
A0127_05005	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
A0127_05010	ENOG4105DDK	oxidoreductase, beta subunit
A0127_05015	ENOG4107XUH	ferredoxin (flavodoxin) oxidoreductase
A0127_05020	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
A0127_05025	ENOG4105DDK	oxidoreductase, beta subunit
A0127_05040	ENOG4105EHG	Permease protein
A0127_05045	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
A0127_05050	ENOG4105D1F	ATP-binding protein
A0127_05075	ENOG4105CJ1	ABC, transporter
A0127_05090	ENOG4108RVA	ribokinase
A0127_05100	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
A0127_05110	ENOG4108UUC	Protein of unknown function DUF99
A0127_05115	ENOG4107YZX	Universal stress protein
A0127_05120	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
A0127_05130	ENOG4105VFR	signal peptidase
A0127_05145	ENOG4108IGT	Dipeptidase
A0127_05190	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
A0127_05235	ENOG4107QXV	Phosphate transporter
A0127_05250	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
A0127_05255	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
A0127_05285	ENOG4107SHJ	sulfite reductase subunit b
A0127_05295	ENOG4105SC1	monovalent cation H antiporter subunit E
A0127_05300	ENOG41080TA	Multiple resistance and ph regulation protein f
A0127_05305	ENOG4105KJM	monovalent cation h antiporter subunit g
A0127_05330	ENOG4108JPZ	Monovalent cation H antiporter subunit D
A0127_05340	ENOG4105C47	NADH ubiquinone oxidoreductase 20 kda subunit
A0127_05345	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
A0127_05350	ENOG4108HM5	NADH-ubiquinone oxidoreductase chain 49kDa
A0127_05355	ENOG4107TDF	Formate hydrogenlyase subunit 4
A0127_05390	ENOG4105C3M	thioredoxin reductase
A0127_05395	ENOG4108JPW	Aminotransferase
A0127_05410	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
A0127_05420	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
A0127_05445	ENOG4105EW9	transcriptional regulator AsnC family
A0127_05470	ENOG4108ZAF	Molybdopterin
A0127_05545	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
A0127_05555	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
A0127_05565	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
A0127_05570	ENOG4105CD5	CoA-binding domain protein
A0127_05590	ENOG4107S5Z	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity)
A0127_05625	ENOG4105C0D	helicase
A0127_05740	ENOG4105EYW	Ion transport protein
A0127_05750	ENOG4105CYV	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures (By similarity)
A0127_05765	ENOG4105CB1	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
A0127_05775	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
A0127_05780	ENOG4105D1H	recombination factor protein RarA
A0127_05795	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
A0127_05805	ENOG4105E5K	Alpha-amylase
A0127_05820	ENOG41082SX	arsR family transcriptional regulator
A0127_05830	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
A0127_05840	ENOG4105VXP	Protein of unknown function DUF86
A0127_05870	ENOG4105C31	Tryptophanyl-tRNA synthetase
A0127_05885	ENOG4105ERH	Fumarylacetoacetate hydrolase
A0127_05895	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
A0127_05900	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
A0127_05935	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
A0127_05960	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
A0127_05980	ENOG4105CTD	carboxy-peptidase
A0127_06010	ENOG4107SCK	Monooxygenase
A0127_06015	ENOG4108KN7	Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity)
A0127_06045	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
A0127_06055	ENOG4105C0H	protease
A0127_06105	ENOG4105C6W	4-alpha-glucanotransferase (EC 2.4.1.25)
A0127_06130	ENOG4105DF0	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity)
A0127_06135	ENOG4105CD3	dihydroorotase
A0127_06150	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
A0127_06155	ENOG4105C3U	ABC transporter
A0127_06160	ENOG4108JQ7	(ABC) transporter
A0127_06170	ENOG4105C4K	Nad synthetase
A0127_06180	ENOG4105C5F	glutamine synthetase
A0127_06220	ENOG4105EHU	Circadian clock protein KaiC
A0127_06240	ENOG4105DR4	Methyltransferase
A0127_06280	ENOG4107XZC	Restriction modification system DNA (Specificity
A0127_06290	ENOG4105DZR	Type I site-specific deoxyribonuclease
A0127_06310	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
A0127_06315	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
A0127_06320	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
A0127_06325	ENOG4105D6M	Phosphoglucomutase Phosphomannomutase
A0127_06345	ENOG4105EG2	ABC transporter, permease
A0127_06350	ENOG4105D56	permease protein
A0127_06355	ENOG4107FKK	extracellular solute-binding protein family 1
A0127_06360	ENOG4108NGU	Transcriptional regulator
A0127_06365	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
A0127_06385	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
A0127_06425	ENOG41081HM	2'-5' rna ligase
A0127_06440	ENOG4105CJ1	ABC, transporter
A0127_06450	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
A0127_06450	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
A0127_06480	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
A0127_06505	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
A0127_06515	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
A0127_06520	ENOG4105CBG	Sulfatase
A0127_06525	ENOG4105K64	Glycosyl transferase, family 2
A0127_06540	ENOG4105D5D	udp-galactopyranose mutase
A0127_06545	ENOG4105CBG	Sulfatase
A0127_06580	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
A0127_06600	ENOG4107V9E	glucose-1-phosphate thymidylyltransferase
A0127_06615	ENOG4105CBG	Sulfatase
A0127_06620	ENOG41076QQ	Glycosyl transferase, family 2
A0127_06630	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
A0127_06650	ENOG4107TSN	permease
A0127_06655	ENOG4107T1U	Catalyzes the synthesis of activated sulfate (By similarity)
A0127_06680	ENOG4107RIQ	Sulfate adenylate transferase
A0127_06745	ENOG4105F0N	pyrophosphate phospho-hydrolase
A0127_06775	ENOG41084T3	4fe-4S ferredoxin iron-sulfur binding domain-containing protein
A0127_06780	ENOG4105VG1	fes assembly suf system protein
A0127_06790	ENOG4108JVH	Protein of unknown function DUF43
A0127_06805	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
A0127_06825	ENOG4105C6T	cysteine synthase
A0127_06835	ENOG4105CDJ	oxidoreductase FAD NAD(P)-binding domain protein
A0127_06840	ENOG4105BZ8	glutamate synthase
A0127_06860	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
A0127_06870	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
A0127_06930	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
A0127_06945	ENOG4105HDK	L-asparaginase
A0127_06955	ENOG4105VUN	Transcriptional regulator
A0127_06960	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
A0127_06970	ENOG4108RWI	nicotinamidase
A0127_06995	ENOG4105DQU	oxidoreductase, subunit beta
A0127_07030	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
A0127_07035	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
A0127_07040	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
A0127_07070	ENOG4105D6E	homoserine dehydrogenase
A0127_07075	ENOG4105C2X	Arabinose 5-phosphate isomerase
A0127_07080	ENOG4105D9Q	decarboxylase (Beta subunit)
A0127_07085	ENOG4107QSA	Oxaloacetate decarboxylase
A0127_07095	ENOG4105D8K	carboxyl transferase
A0127_07130	ENOG4105CKX	Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP
A0127_07135	ENOG4105DPX	Hydrogenase, large subunit
A0127_07145	ENOG4105DF0	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity)
A0127_07155	ENOG4105GKE	subunit e
A0127_07160	ENOG4107QIZ	NADH dehydrogenase
A0127_07190	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
A0127_07195	ENOG4105EC8	Methyl-accepting chemotaxis
A0127_07220	ENOG4108JIQ	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit (By similarity)
A0127_07225	ENOG4105KXQ	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
A0127_07235	ENOG4105K4G	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
A0127_07255	ENOG4105C1A	potassium transporter peripheral membrane
A0127_07260	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
A0127_07265	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
A0127_07270	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
A0127_07280	ENOG4105EHU	Circadian clock protein KaiC
A0127_07300	ENOG4107XF7	NGG1p interacting factor 3 protein, NIF3
A0127_07315	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
A0127_07335	ENOG4105CUT	histidyl-tRNA synthetase
A0127_07340	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
A0127_07355	ENOG4105C8Q	Methyl-accepting chemotaxis
A0127_07370	ENOG4107RWR	Sodium hydrogen exchanger
A0127_07375	ENOG4107RWR	Sodium hydrogen exchanger
A0127_07380	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
A0127_07385	ENOG4105DZ0	fad dependent oxidoreductase
A0127_07390	ENOG4107R56	PP-loop domain protein
A0127_07415	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
A0127_07420	ENOG4105C5S	asparaginyl-tRNA synthetase
A0127_07430	ENOG4107STF	Involved in phosphonate degradation (By similarity)
A0127_07470	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
A0127_07480	ENOG41080UE	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
A0127_07485	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
A0127_07490	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
A0127_07500	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
A0127_07505	ENOG41082SA	50s ribosomal protein l29
A0127_07520	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
A0127_07525	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
A0127_07530	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
A0127_07540	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
A0127_07550	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
A0127_07555	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
A0127_07570	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
A0127_07575	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
A0127_07580	ENOG4105VPB	50S ribosomal protein L30
A0127_07585	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
A0127_07610	ENOG4108Z4J	Cytidine monophosphate kinase
A0127_07620	ENOG4105CHR	reductase
A0127_07625	ENOG41071TK	Uncharacterised protein family (UPF0150)
A0127_07630	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
A0127_07640	ENOG4107Y49	methyltransferase
A0127_07650	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
A0127_07655	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
A0127_07660	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
A0127_07665	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
A0127_07680	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
A0127_07685	ENOG4108UJD	30S ribosomal protein S9
A0127_07705	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
A0127_07710	ENOG4105CE9	30S ribosomal protein S2
A0127_07725	ENOG4105K7K	Transcriptional regulator
A0127_07745	ENOG4108YXU	transcriptional regulator AsnC family
A0127_07755	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
A0127_07770	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
A0127_07785	ENOG4105CB1	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
A0127_07790	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
A0127_07810	ENOG4108I5U	Uridine phosphorylase
A0127_07815	ENOG4108IYI	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
A0127_07820	ENOG41074MP	UPF0103 Mediator of ErbB2-driven cell motility-containing protein
A0127_07825	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
A0127_07840	ENOG4105CEV	competence damage-inducible protein
A0127_07850	ENOG4106UJV	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
A0127_07870	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
A0127_07870	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
A0127_07885	ENOG4105C8T	Leucyl-tRNA synthetase
A0127_07915	ENOG4108JEB	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
A0127_07930	ENOG4105MRR	Transcriptional regulator (By similarity)
A0127_07945	ENOG4107RFW	hydrolase family 57
A0127_07950	ENOG4108YZA	Nitrogen regulatory protein pii
A0127_07960	ENOG4105C8J	)-transporter
A0127_07965	ENOG4105D82	Glutamate dehydrogenase
A0127_07975	ENOG4105KPK	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation (By similarity)
A0127_07980	ENOG4105CY0	Metallo-Beta-Lactamase
A0127_07990	ENOG4105E66	phosphoriboisomerase A
A0127_08015	ENOG4108T9Q	UPF0278 protein
A0127_08035	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
A0127_08050	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
A0127_08055	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
A0127_08075	ENOG4105DHP	deoxycytidine triphosphate deaminase
A0127_08105	ENOG4105CX6	glutaminyL-tRNA synthetase
A0127_08115	ENOG4107R76	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
A0127_08120	ENOG4105C0M	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity)
A0127_08130	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
A0127_08140	ENOG4107TE1	transport protein
A0127_08150	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
A0127_08155	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
A0127_08160	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
A0127_08170	ENOG4108JU3	Alkyl hydroperoxide reductase
A0127_08230	ENOG4107RGW	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
A0127_08250	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
A0127_08255	ENOG4105C8Q	Methyl-accepting chemotaxis
A0127_08260	ENOG4105UQX	Mate efflux family protein
A0127_08315	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
A0127_08345	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
A0127_08370	ENOG4105C9B	Cysteine desulfurase
A0127_08385	ENOG4105C45	hydrogenase expression formation protein (HypE)
A0127_08400	ENOG41090A1	ferritin
A0127_08405	ENOG4107EEM	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
A0127_08415	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
A0127_08445	ENOG4105C11	sulfate adenylyltransferase), subunit 2
A0127_08450	ENOG4107QX8	SPFH domain, Band 7 family protein
A0127_08460	ENOG4107104	thymidine kinase
A0127_08490	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
A0127_08530	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
A0127_08535	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
A0127_08540	ENOG4105CIH	Imidazole acetol-phosphate transaminase
A0127_08545	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
A0127_08570	ENOG4108UHF	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
A0127_08610	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
A0127_08625	ENOG4105KTU	Transcriptional regulator, arsr family
A0127_08630	ENOG4108ZPQ	MazG nucleotide pyrophosphohydrolase
A0127_08635	ENOG4108VVK	transcriptional Regulator, AsnC
A0127_08645	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
A0127_08665	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
A0127_08725	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
A0127_08730	ENOG4105C75	arginyL-tRNA synthetase
A0127_08760	ENOG4108IJ1	Dehydrogenase
A0127_08765	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
A0127_08785	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
A0127_08795	ENOG4105SC1	monovalent cation H antiporter subunit E
A0127_08805	ENOG4105KJM	monovalent cation h antiporter subunit g
A0127_08815	ENOG4105D65	subunit l
A0127_08820	ENOG4108ZE9	Monovalent cation H antiporter subunit C
A0127_08825	ENOG4108JPZ	Monovalent cation H antiporter subunit D
A0127_08830	ENOG4108JPZ	Monovalent cation H antiporter subunit D
A0127_08840	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
A0127_08845	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
A0127_08850	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
A0127_08870	ENOG4108JPW	Aminotransferase
A0127_08900	ENOG4108V1U	phospholipid-binding protein
A0127_08905	ENOG4105CHR	reductase
A0127_08940	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
A0127_08945	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
A0127_08970	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
A0127_08985	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
A0127_09000	ENOG4107V9E	glucose-1-phosphate thymidylyltransferase
A0127_09010	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
A0127_09020	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
A0127_09025	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
A0127_09030	ENOG4108JJB	ABC transporter
A0127_09050	ENOG4105CN9	Peptidase m42 family protein
A0127_09065	ENOG4108Z0R	Transferase
A0127_09070	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
A0127_09085	ENOG4105C22	threonyL-tRNA synthetase
A0127_09125	ENOG4105F4G	Membrane
A0127_09130	ENOG4105EEI	dihydropteroate synthase
A0127_09155	ENOG4107Y70	Heat shock protein
A0127_09200	ENOG4105BZA	Phosphoglycerate kinase
A0127_09220	ENOG4105CSM	endonuclease III
A0127_09225	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
A0127_09245	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
A0127_09265	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
A0127_09270	ENOG4105DQU	oxidoreductase, subunit beta
A0127_09280	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
A0127_09285	ENOG4105DQU	oxidoreductase, subunit beta
A0127_09310	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
A0127_09320	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
A0127_09325	ENOG4105CNW	domain protein
A0127_09340	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
A0127_09350	ENOG4107UX3	phosphatidylethanolamine N-methyltransferase
A0127_09355	ENOG4107UA9	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) (By similarity)
A0127_09360	ENOG4108JJB	ABC transporter
A0127_09370	ENOG4105D65	subunit l
A0127_09375	ENOG4105C8S	subunit m
A0127_09385	ENOG4105KJM	monovalent cation h antiporter subunit g
A0127_09400	ENOG4105MKQ	Monovalent cation H antiporter subunit C
A0127_09405	ENOG4105SC1	monovalent cation H antiporter subunit E
A0127_09410	ENOG4108JPZ	Monovalent cation H antiporter subunit D
A0127_09420	ENOG41080XS	Cobyrinic acid ac-diamide synthase
A0127_09430	ENOG4105CQS	hydrogenase expression formation protein HypD
A0127_09435	ENOG4105WRB	Hydrogenase assembly chaperone hypC hupF
A0127_09450	ENOG41067SE	Tetr family transcriptional regulator
A0127_09455	ENOG4108IEG	Formate dehydrogenase Alpha subunit
A0127_09460	ENOG4105QAX	Iron-sulfur
A0127_09465	ENOG4105D65	subunit l
A0127_09470	ENOG4108JPZ	Monovalent cation H antiporter subunit D
A0127_09475	ENOG4107TDF	Formate hydrogenlyase subunit 4
A0127_09480	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
A0127_09485	ENOG4108RG7	formate hydrogenlyase complex iron-sulfur subunit
A0127_09490	ENOG4105C47	NADH ubiquinone oxidoreductase 20 kda subunit
A0127_09505	ENOG41083NF	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
A0127_09520	ENOG4105WMM	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
A0127_09525	ENOG4105PGM	cation diffusion facilitator family transporter
A0127_09545	ENOG4105DIW	FeS assembly protein SUFB
A0127_09550	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
A0127_09620	ENOG4105WE2	aldehyde ferredoxin oxidoreductase
A0127_09625	ENOG4108MFN	small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex)
A0127_09655	ENOG4105WE2	aldehyde ferredoxin oxidoreductase
A0127_09665	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
A0127_09680	ENOG4108Y83	glucose-6-phosphate isomerase
A0127_09695	ENOG4108JJB	ABC transporter
A0127_09705	ENOG4105G01	cobalamin (vitamin B12) biosynthesis CbiM protein
A0127_09710	ENOG4105CFT	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import (By similarity)
A0127_09725	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
A0127_09755	ENOG4105CHM	Aminotransferase
A0127_09770	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
A0127_09785	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
A0127_09800	ENOG4108JU3	Alkyl hydroperoxide reductase
A0127_09810	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
A0127_09820	ENOG4107QR0	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
A0127_09840	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
A0127_09865	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
A0127_09875	ENOG4105WE2	aldehyde ferredoxin oxidoreductase
A0127_09890	ENOG41060GT	Translocates 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane (By similarity)
A0127_09920	ENOG4105N80	Ferric uptake regulator, Fur family
A0127_09940	ENOG4105HF0	Membrane
A0127_09975	ENOG4105EHU	Circadian clock protein KaiC
A0127_09980	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
A0127_09990	ENOG4108WBT	adenosyltransferase
A0127_10010	ENOG4107YCR	Transcriptional regulator, ARSR family
A0127_10030	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
A0127_10035	ENOG4105C2X	Arabinose 5-phosphate isomerase
A0127_10065	ENOG4105D6J	arsenicaL-resistance protein
A0127_10085	ENOG4105K63	Thioredoxin
A0127_10135	ENOG4105C28	cystathionine
A0127_10170	ENOG4108ZF3	Phosphatase
A0127_10180	ENOG4105D9P	serine threonine protein kinase
A0127_10300	ENOG4105EKT	)-iron permease
A0127_10305	ENOG4105D3R	alkyl hydroperoxide reductase