A0127_02070 f49af227bff04258e15000613a502fff 431 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 220 236 - T 23-10-2018 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 A0127_02070 f49af227bff04258e15000613a502fff 431 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 5 418 43.705 T 23-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 A0127_02070 f49af227bff04258e15000613a502fff 431 Pfam PF00464 Serine hydroxymethyltransferase 10 390 2.3E-81 T 23-10-2018 IPR039429 Serine hydroxymethyltransferase-like domain KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 A0127_02070 f49af227bff04258e15000613a502fff 431 Gene3D G3DSA:3.40.640.10 38 280 1.7E-84 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A0127_02070 f49af227bff04258e15000613a502fff 431 Gene3D G3DSA:3.90.1150.10 281 428 1.1E-53 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A0127_02070 f49af227bff04258e15000613a502fff 431 PIRSF PIRSF000412 4 424 1.2E-145 T 23-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 A0127_02070 f49af227bff04258e15000613a502fff 431 SUPERFAMILY SSF53383 6 424 6.86E-134 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A0127_03520 61536ac1f023db7711ff4f9f83916640 252 SMART SM00382 28 211 1.2E-9 T 23-10-2018 IPR003593 AAA+ ATPase domain A0127_03520 61536ac1f023db7711ff4f9f83916640 252 Pfam PF00005 ABC transporter 19 162 9.7E-29 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A0127_03520 61536ac1f023db7711ff4f9f83916640 252 SUPERFAMILY SSF52540 6 227 6.16E-61 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_03520 61536ac1f023db7711ff4f9f83916640 252 Gene3D G3DSA:3.40.50.300 1 243 3.0E-69 T 23-10-2018 A0127_05750 e5abcd958cd60fe04854d6f1e0e1da47 223 Hamap MF_00722 Endonuclease NucS [nucS]. 1 214 38.75 T 23-10-2018 IPR002793 Endonuclease NucS GO:0004519 A0127_05750 e5abcd958cd60fe04854d6f1e0e1da47 223 Pfam PF01939 Endonuclease NucS 2 218 7.5E-88 T 23-10-2018 IPR002793 Endonuclease NucS GO:0004519 A0127_05750 e5abcd958cd60fe04854d6f1e0e1da47 223 Gene3D G3DSA:3.40.1350.10 97 209 1.3E-43 T 23-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 A0127_05750 e5abcd958cd60fe04854d6f1e0e1da47 223 Gene3D G3DSA:2.70.180.20 1 96 1.5E-38 T 23-10-2018 A0127_08120 06095f296d74b6b389493a2b3725c65d 623 Gene3D G3DSA:3.90.228.20 247 603 1.8E-145 T 23-10-2018 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 A0127_08120 06095f296d74b6b389493a2b3725c65d 623 SUPERFAMILY SSF53795 244 604 2.29E-106 T 23-10-2018 A0127_08120 06095f296d74b6b389493a2b3725c65d 623 Hamap MF_00452 Phosphoenolpyruvate carboxykinase [GTP] [pckG]. 18 605 36.294 T 23-10-2018 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 A0127_08120 06095f296d74b6b389493a2b3725c65d 623 Gene3D G3DSA:2.170.8.10 65 398 1.8E-145 T 23-10-2018 A0127_08120 06095f296d74b6b389493a2b3725c65d 623 Pfam PF00821 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain 244 604 2.3E-103 T 23-10-2018 IPR035077 Phosphoenolpyruvate carboxykinase, GTP-utilising, C-terminal GO:0004611|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 A0127_08120 06095f296d74b6b389493a2b3725c65d 623 Pfam PF17297 Phosphoenolpyruvate carboxykinase N-terminal domain 29 239 5.1E-60 T 23-10-2018 IPR035078 Phosphoenolpyruvate carboxykinase, GTP-utilising, N-terminal GO:0004611|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 A0127_08120 06095f296d74b6b389493a2b3725c65d 623 ProSitePatterns PS00505 Phosphoenolpyruvate carboxykinase (GTP) signature. 268 276 - T 23-10-2018 IPR018091 Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site GO:0004613 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 A0127_08120 06095f296d74b6b389493a2b3725c65d 623 PIRSF PIRSF001348 5 608 1.9E-209 T 23-10-2018 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 A0127_08120 06095f296d74b6b389493a2b3725c65d 623 SUPERFAMILY SSF68923 11 243 2.67E-65 T 23-10-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 A0127_08120 06095f296d74b6b389493a2b3725c65d 623 Gene3D G3DSA:3.40.449.10 27 246 1.8E-145 T 23-10-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 A0127_01390 afc2211da9698c2aba01ca4df7a4efdb 166 SUPERFAMILY SSF53146 1 112 6.93E-30 T 23-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily A0127_01390 afc2211da9698c2aba01ca4df7a4efdb 166 Gene3D G3DSA:3.30.420.130 1 115 1.8E-30 T 23-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily A0127_01390 afc2211da9698c2aba01ca4df7a4efdb 166 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 13 106 8.1E-22 T 23-10-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis A0127_07165 c287379e7052a7a0647626f01d0be230 951 SUPERFAMILY SSF53706 702 942 7.97E-17 T 23-10-2018 A0127_07165 c287379e7052a7a0647626f01d0be230 951 ProSitePatterns PS00641 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. 30 47 - T 23-10-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A0127_07165 c287379e7052a7a0647626f01d0be230 951 SUPERFAMILY SSF54862 579 693 1.26E-19 T 23-10-2018 A0127_07165 c287379e7052a7a0647626f01d0be230 951 Gene3D G3DSA:3.30.70.20 612 693 2.8E-14 T 23-10-2018 A0127_07165 c287379e7052a7a0647626f01d0be230 951 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 188 481 5.9E-42 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A0127_07165 c287379e7052a7a0647626f01d0be230 951 SUPERFAMILY SSF46548 94 198 1.36E-21 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 A0127_07165 c287379e7052a7a0647626f01d0be230 951 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 97 175 1.4E-18 T 23-10-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 A0127_07165 c287379e7052a7a0647626f01d0be230 951 SUPERFAMILY SSF51971 186 428 1.06E-75 T 23-10-2018 A0127_07165 c287379e7052a7a0647626f01d0be230 951 PRINTS PR00419 Adrenodoxin reductase family signature 320 334 3.3E-23 T 23-10-2018 A0127_07165 c287379e7052a7a0647626f01d0be230 951 PRINTS PR00419 Adrenodoxin reductase family signature 189 211 3.3E-23 T 23-10-2018 A0127_07165 c287379e7052a7a0647626f01d0be230 951 PRINTS PR00419 Adrenodoxin reductase family signature 353 366 3.3E-23 T 23-10-2018 A0127_07165 c287379e7052a7a0647626f01d0be230 951 PRINTS PR00419 Adrenodoxin reductase family signature 254 264 3.3E-23 T 23-10-2018 A0127_07165 c287379e7052a7a0647626f01d0be230 951 PRINTS PR00419 Adrenodoxin reductase family signature 212 225 3.3E-23 T 23-10-2018 A0127_07165 c287379e7052a7a0647626f01d0be230 951 Gene3D G3DSA:3.50.50.60 186 312 1.6E-38 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A0127_07165 c287379e7052a7a0647626f01d0be230 951 Gene3D G3DSA:3.50.50.60 315 514 1.1E-30 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A0127_07165 c287379e7052a7a0647626f01d0be230 951 Gene3D G3DSA:1.10.1060.10 89 185 4.8E-25 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 A0127_07165 c287379e7052a7a0647626f01d0be230 951 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 2 73 2.6E-8 T 23-10-2018 A0127_07165 c287379e7052a7a0647626f01d0be230 951 Gene3D G3DSA:2.20.25.90 705 755 3.1E-5 T 23-10-2018 A0127_07165 c287379e7052a7a0647626f01d0be230 951 SUPERFAMILY SSF54292 1 96 2.42E-20 T 23-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 A0127_09770 317a0189f0652bd7c1afae9965fbc89d 720 SUPERFAMILY SSF56712 2 651 1.22E-164 T 23-10-2018 IPR023405 DNA topoisomerase, type IA, core domain A0127_09770 317a0189f0652bd7c1afae9965fbc89d 720 Pfam PF01131 DNA topoisomerase 156 564 5.4E-134 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A0127_09770 317a0189f0652bd7c1afae9965fbc89d 720 SMART SM00437 271 527 3.0E-106 T 23-10-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 A0127_09770 317a0189f0652bd7c1afae9965fbc89d 720 Gene3D G3DSA:1.10.290.10 279 406 4.6E-124 T 23-10-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 A0127_09770 317a0189f0652bd7c1afae9965fbc89d 720 Gene3D G3DSA:1.10.460.10 163 575 4.6E-124 T 23-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 A0127_09770 317a0189f0652bd7c1afae9965fbc89d 720 SMART SM00436 131 226 8.8E-42 T 23-10-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 A0127_09770 317a0189f0652bd7c1afae9965fbc89d 720 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 638 676 4.1E-14 T 23-10-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 A0127_09770 317a0189f0652bd7c1afae9965fbc89d 720 SUPERFAMILY SSF57783 634 678 4.42E-6 T 23-10-2018 A0127_09770 317a0189f0652bd7c1afae9965fbc89d 720 Gene3D G3DSA:3.40.50.140 1 154 1.4E-30 T 23-10-2018 A0127_09770 317a0189f0652bd7c1afae9965fbc89d 720 SMART SM00493 2 129 1.9E-19 T 23-10-2018 IPR006171 TOPRIM domain A0127_09770 317a0189f0652bd7c1afae9965fbc89d 720 TIGRFAM TIGR01057 topA_arch: DNA topoisomerase I 6 669 1.8E-286 T 23-10-2018 IPR005739 DNA topoisomerase I, archeal-type GO:0003677|GO:0003916|GO:0006265 A0127_09770 317a0189f0652bd7c1afae9965fbc89d 720 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 392 408 2.0E-25 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A0127_09770 317a0189f0652bd7c1afae9965fbc89d 720 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 196 214 2.0E-25 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A0127_09770 317a0189f0652bd7c1afae9965fbc89d 720 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 491 505 2.0E-25 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A0127_09770 317a0189f0652bd7c1afae9965fbc89d 720 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 103 116 2.0E-25 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A0127_09770 317a0189f0652bd7c1afae9965fbc89d 720 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 313 322 2.0E-25 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A0127_09770 317a0189f0652bd7c1afae9965fbc89d 720 Pfam PF01751 Toprim domain 3 139 2.5E-18 T 23-10-2018 IPR006171 TOPRIM domain A0127_09770 317a0189f0652bd7c1afae9965fbc89d 720 Gene3D G3DSA:2.70.20.10 220 475 4.6E-124 T 23-10-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 A0127_09770 317a0189f0652bd7c1afae9965fbc89d 720 Hamap MF_00952 DNA topoisomerase 1 [topA]. 2 708 50.732 T 23-10-2018 IPR028612 DNA topoisomerase I, type IA GO:0003677|GO:0003916|GO:0006265 A0127_03865 67fde2aa2fad171f8b2f00228cad6ba1 416 Gene3D G3DSA:1.10.1510.30 171 256 4.9E-119 T 23-10-2018 A0127_03865 67fde2aa2fad171f8b2f00228cad6ba1 416 Hamap MF_01082 tRNA pseudouridine synthase D [truD]. 8 416 29.825 T 23-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 A0127_03865 67fde2aa2fad171f8b2f00228cad6ba1 416 TIGRFAM TIGR00094 tRNA_TruD_broad: tRNA pseudouridine synthase, TruD family 12 415 1.6E-85 T 23-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 A0127_03865 67fde2aa2fad171f8b2f00228cad6ba1 416 ProSitePatterns PS01268 Uncharacterized protein family UPF0024 signature. 80 93 - T 23-10-2018 IPR020119 Pseudouridine synthase TruD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 Reactome: R-HSA-6782315 A0127_03865 67fde2aa2fad171f8b2f00228cad6ba1 416 SUPERFAMILY SSF55120 7 414 1.22E-93 T 23-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 A0127_03865 67fde2aa2fad171f8b2f00228cad6ba1 416 Gene3D G3DSA:3.30.70.3160 43 125 4.9E-119 T 23-10-2018 A0127_03865 67fde2aa2fad171f8b2f00228cad6ba1 416 Pfam PF01142 tRNA pseudouridine synthase D (TruD) 11 412 3.5E-136 T 23-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 A0127_03865 67fde2aa2fad171f8b2f00228cad6ba1 416 Gene3D G3DSA:3.30.2350.20 126 411 4.9E-119 T 23-10-2018 A0127_03865 67fde2aa2fad171f8b2f00228cad6ba1 416 PIRSF PIRSF037016 32 391 2.3E-65 T 23-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 A0127_03865 67fde2aa2fad171f8b2f00228cad6ba1 416 PIRSF PIRSF037016 389 416 0.0012 T 23-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 A0127_07485 40a15da27c34688a83821a36d7e32bb5 239 Gene3D G3DSA:2.30.30.30 85 162 7.4E-30 T 23-10-2018 IPR014722 Ribosomal protein L2, domain 2 A0127_07485 40a15da27c34688a83821a36d7e32bb5 239 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 11 84 2.4E-21 T 23-10-2018 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 A0127_07485 40a15da27c34688a83821a36d7e32bb5 239 SUPERFAMILY SSF50104 94 237 6.02E-48 T 23-10-2018 IPR008991 Translation protein SH3-like domain superfamily A0127_07485 40a15da27c34688a83821a36d7e32bb5 239 PIRSF PIRSF002158 1 239 7.9E-73 T 23-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A0127_07485 40a15da27c34688a83821a36d7e32bb5 239 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 93 222 1.7E-42 T 23-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 A0127_07485 40a15da27c34688a83821a36d7e32bb5 239 SMART SM01382 91 223 7.0E-61 T 23-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 A0127_07485 40a15da27c34688a83821a36d7e32bb5 239 SMART SM01383 11 85 3.6E-27 T 23-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A0127_07485 40a15da27c34688a83821a36d7e32bb5 239 Gene3D G3DSA:4.10.950.10 163 239 3.4E-34 T 23-10-2018 IPR014726 Ribosomal protein L2, domain 3 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_07485 40a15da27c34688a83821a36d7e32bb5 239 SUPERFAMILY SSF50249 2 92 2.81E-24 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A0127_07485 40a15da27c34688a83821a36d7e32bb5 239 Hamap MF_01320_A 50S ribosomal protein L2 [rplB]. 1 238 42.578 T 23-10-2018 IPR023672 Ribosomal protein L2, archaeal-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_07485 40a15da27c34688a83821a36d7e32bb5 239 Gene3D G3DSA:2.40.50.140 1 81 3.5E-31 T 23-10-2018 A0127_00435 5c0465194b8d1240588c868cd93857ad 256 Pfam PF01261 Xylose isomerase-like TIM barrel 22 219 1.7E-34 T 23-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain A0127_00435 5c0465194b8d1240588c868cd93857ad 256 SMART SM00518 2 255 0.0024 T 23-10-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 A0127_00435 5c0465194b8d1240588c868cd93857ad 256 SUPERFAMILY SSF51658 17 242 5.24E-50 T 23-10-2018 IPR036237 Xylose isomerase-like superfamily A0127_00435 5c0465194b8d1240588c868cd93857ad 256 Gene3D G3DSA:3.20.20.150 1 255 2.4E-61 T 23-10-2018 A0127_05625 e2ede95c962c1a442ea0d2e417105274 1000 Gene3D G3DSA:3.40.50.300 360 540 3.9E-33 T 23-10-2018 A0127_05625 e2ede95c962c1a442ea0d2e417105274 1000 SUPERFAMILY SSF52540 150 549 1.39E-42 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_05625 e2ede95c962c1a442ea0d2e417105274 1000 Pfam PF13020 Domain of unknown function (DUF3883) 870 956 1.7E-15 T 23-10-2018 IPR024975 Domain of unknown function DUF3883 A0127_05625 e2ede95c962c1a442ea0d2e417105274 1000 Pfam PF00271 Helicase conserved C-terminal domain 393 509 3.7E-20 T 23-10-2018 IPR001650 Helicase, C-terminal A0127_05625 e2ede95c962c1a442ea0d2e417105274 1000 SUPERFAMILY SSF52540 30 240 1.0E-33 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_05625 e2ede95c962c1a442ea0d2e417105274 1000 Gene3D G3DSA:3.40.50.10810 35 334 2.9E-49 T 23-10-2018 IPR038718 SNF2-like, N-terminal domain superfamily A0127_05625 e2ede95c962c1a442ea0d2e417105274 1000 Pfam PF00176 SNF2 family N-terminal domain 57 240 1.1E-13 T 23-10-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 A0127_05625 e2ede95c962c1a442ea0d2e417105274 1000 SMART SM00490 432 510 3.3E-17 T 23-10-2018 IPR001650 Helicase, C-terminal A0127_05625 e2ede95c962c1a442ea0d2e417105274 1000 SMART SM00487 33 223 2.2E-22 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A0127_06090 04cb324ac2378f7d793bad0d997944db 231 SUPERFAMILY SSF56784 3 222 9.47E-38 T 23-10-2018 IPR036412 HAD-like superfamily A0127_06090 04cb324ac2378f7d793bad0d997944db 231 Gene3D G3DSA:1.10.150.520 14 96 3.2E-36 T 23-10-2018 A0127_06090 04cb324ac2378f7d793bad0d997944db 231 Pfam PF13419 Haloacid dehalogenase-like hydrolase 3 194 4.6E-22 T 23-10-2018 A0127_06090 04cb324ac2378f7d793bad0d997944db 231 Gene3D G3DSA:3.40.50.1000 3 216 3.2E-36 T 23-10-2018 IPR023214 HAD superfamily A0127_06090 04cb324ac2378f7d793bad0d997944db 231 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 91 188 7.0E-11 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A0127_02265 17380094ba5aab8325dcecbfa5ee92e3 432 SUPERFAMILY SSF53639 254 427 1.26E-54 T 23-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily A0127_02265 17380094ba5aab8325dcecbfa5ee92e3 432 Pfam PF08543 Phosphomethylpyrimidine kinase 10 244 8.8E-70 T 23-10-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 A0127_02265 17380094ba5aab8325dcecbfa5ee92e3 432 Gene3D G3DSA:3.40.225.10 250 431 7.3E-63 T 23-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily A0127_02265 17380094ba5aab8325dcecbfa5ee92e3 432 Gene3D G3DSA:3.40.1190.20 1 248 2.0E-68 T 23-10-2018 IPR029056 Ribokinase-like A0127_02265 17380094ba5aab8325dcecbfa5ee92e3 432 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 3 236 6.2E-65 T 23-10-2018 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A0127_02265 17380094ba5aab8325dcecbfa5ee92e3 432 Pfam PF10120 Thiamine-phosphate synthase 260 425 3.7E-53 T 23-10-2018 IPR019293 Thiamine-phosphate synthase ThiN GO:0004789 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A0127_02265 17380094ba5aab8325dcecbfa5ee92e3 432 SUPERFAMILY SSF53613 3 253 1.08E-58 T 23-10-2018 IPR029056 Ribokinase-like A0127_03995 226a9e8314646453d67a9ccee1283746 149 Hamap MF_02115 FAD synthase [ribL]. 8 148 30.046 T 23-10-2018 IPR024902 FAD synthase RibL GO:0003919|GO:0006747|GO:0046444 KEGG: 00740+2.7.7.2|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A0127_03995 226a9e8314646453d67a9ccee1283746 149 Gene3D G3DSA:3.40.50.620 1 147 8.9E-42 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A0127_03995 226a9e8314646453d67a9ccee1283746 149 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 9 75 4.5E-21 T 23-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 A0127_03995 226a9e8314646453d67a9ccee1283746 149 Pfam PF01467 Cytidylyltransferase-like 11 142 2.3E-24 T 23-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 A0127_03995 226a9e8314646453d67a9ccee1283746 149 SUPERFAMILY SSF52374 8 143 2.17E-27 T 23-10-2018 A0127_06010 b96e08b93b12b3bc6360ee078a29f093 371 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 134 149 3.6E-11 T 23-10-2018 A0127_06010 b96e08b93b12b3bc6360ee078a29f093 371 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 3.6E-11 T 23-10-2018 A0127_06010 b96e08b93b12b3bc6360ee078a29f093 371 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 245 260 3.6E-11 T 23-10-2018 A0127_06010 b96e08b93b12b3bc6360ee078a29f093 371 SUPERFAMILY SSF51905 3 284 6.79E-32 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A0127_06010 b96e08b93b12b3bc6360ee078a29f093 371 TIGRFAM TIGR02032 GG-red-SF: geranylgeranyl reductase family 3 273 2.2E-50 T 23-10-2018 IPR011777 Geranylgeranyl reductase family GO:0016628|GO:0055114 A0127_06010 b96e08b93b12b3bc6360ee078a29f093 371 Gene3D G3DSA:3.50.50.60 1 369 7.3E-58 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A0127_06010 b96e08b93b12b3bc6360ee078a29f093 371 Pfam PF01494 FAD binding domain 3 282 2.5E-14 T 23-10-2018 IPR002938 FAD-binding domain GO:0071949 A0127_06780 f02f4d2fe3ee3609a899ecec8d1a4018 177 SUPERFAMILY SSF117916 78 175 1.5E-32 T 23-10-2018 IPR034904 Fe-S cluster assembly domain superfamily A0127_06780 f02f4d2fe3ee3609a899ecec8d1a4018 177 Pfam PF01883 Iron-sulfur cluster assembly protein 81 154 1.6E-21 T 23-10-2018 IPR002744 MIP18 family-like A0127_06780 f02f4d2fe3ee3609a899ecec8d1a4018 177 Gene3D G3DSA:3.30.300.130 72 177 1.7E-36 T 23-10-2018 IPR034904 Fe-S cluster assembly domain superfamily A0127_02165 7152b53b0e8b1c83333fbaeee8863cf4 49 Pfam PF03604 DNA directed RNA polymerase, 7 kDa subunit 6 39 1.3E-10 T 23-10-2018 IPR006591 RNA polymerase archaeal subunit P/eukaryotic subunit RPABC4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A0127_02165 7152b53b0e8b1c83333fbaeee8863cf4 49 Gene3D G3DSA:2.20.28.30 1 49 8.4E-25 T 23-10-2018 A0127_02165 7152b53b0e8b1c83333fbaeee8863cf4 49 Hamap MF_00615 DNA-directed RNA polymerase subunit P [rpoP]. 6 49 16.49 T 23-10-2018 IPR023464 DNA-directed RNA polymerase subunit P (Rpo12) GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A0127_02165 7152b53b0e8b1c83333fbaeee8863cf4 49 SUPERFAMILY SSF63393 4 48 1.05E-12 T 23-10-2018 IPR029040 RNA polymerase subunit RPABC4/transcription elongation factor Spt4 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-75955 A0127_02165 7152b53b0e8b1c83333fbaeee8863cf4 49 SMART SM00659 4 49 8.8E-20 T 23-10-2018 IPR006591 RNA polymerase archaeal subunit P/eukaryotic subunit RPABC4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A0127_08030 c78706dd61caaad6a1d379b0b4febb26 272 Pfam PF04414 D-aminoacyl-tRNA deacylase 69 269 4.1E-69 T 23-10-2018 IPR007508 D-aminoacyl-tRNA deacylase DtdA GO:0016788|GO:0051499 A0127_08030 c78706dd61caaad6a1d379b0b4febb26 272 SUPERFAMILY SSF142535 1 271 9.29E-89 T 23-10-2018 A0127_08030 c78706dd61caaad6a1d379b0b4febb26 272 Gene3D G3DSA:3.40.630.50 1 186 7.5E-71 T 23-10-2018 A0127_08030 c78706dd61caaad6a1d379b0b4febb26 272 PIRSF PIRSF016210 1 272 9.1E-87 T 23-10-2018 IPR018033 D-aminoacyl-tRNA deacylase, archaea GO:0016788|GO:0019478|GO:0051499 A0127_08030 c78706dd61caaad6a1d379b0b4febb26 272 Hamap MF_00562 D-aminoacyl-tRNA deacylase [dtdA]. 1 271 35.907 T 23-10-2018 IPR018033 D-aminoacyl-tRNA deacylase, archaea GO:0016788|GO:0019478|GO:0051499 A0127_08030 c78706dd61caaad6a1d379b0b4febb26 272 Gene3D G3DSA:3.40.50.10700 187 272 2.3E-32 T 23-10-2018 A0127_08500 9c2c54b1718ec8a506c771a89aefa646 300 ProSitePatterns PS00782 Transcription factor TFIIB repeat signature. 148 163 - T 23-10-2018 IPR023486 Transcription factor TFIIB, conserved site Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-674695|Reactome: R-HSA-6807505|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-76042 A0127_08500 9c2c54b1718ec8a506c771a89aefa646 300 Gene3D G3DSA:1.10.472.170 6 197 2.4E-68 T 23-10-2018 A0127_08500 9c2c54b1718ec8a506c771a89aefa646 300 ProSitePatterns PS00782 Transcription factor TFIIB repeat signature. 244 259 - T 23-10-2018 IPR023486 Transcription factor TFIIB, conserved site Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-674695|Reactome: R-HSA-6807505|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-76042 A0127_08500 9c2c54b1718ec8a506c771a89aefa646 300 SUPERFAMILY SSF47954 206 298 7.48E-31 T 23-10-2018 IPR036915 Cyclin-like superfamily A0127_08500 9c2c54b1718ec8a506c771a89aefa646 300 SMART SM00385 210 291 2.3E-14 T 23-10-2018 IPR013763 Cyclin-like A0127_08500 9c2c54b1718ec8a506c771a89aefa646 300 SMART SM00385 114 195 1.1E-11 T 23-10-2018 IPR013763 Cyclin-like A0127_08500 9c2c54b1718ec8a506c771a89aefa646 300 Hamap MF_00383 Transcription initiation factor IIB [tfb]. 1 297 44.961 T 23-10-2018 IPR023484 Transcription initiation factor TFIIB, archaea A0127_08500 9c2c54b1718ec8a506c771a89aefa646 300 Gene3D G3DSA:1.10.472.10 207 300 5.8E-30 T 23-10-2018 A0127_08500 9c2c54b1718ec8a506c771a89aefa646 300 Pfam PF00382 Transcription factor TFIIB repeat 117 186 1.0E-20 T 23-10-2018 IPR013150 Transcription factor TFIIB, cyclin-like domain GO:0017025 A0127_08500 9c2c54b1718ec8a506c771a89aefa646 300 Pfam PF00382 Transcription factor TFIIB repeat 212 282 9.4E-24 T 23-10-2018 IPR013150 Transcription factor TFIIB, cyclin-like domain GO:0017025 A0127_08500 9c2c54b1718ec8a506c771a89aefa646 300 SUPERFAMILY SSF47954 108 199 4.62E-28 T 23-10-2018 IPR036915 Cyclin-like superfamily A0127_08500 9c2c54b1718ec8a506c771a89aefa646 300 PRINTS PR00685 Transcription initiation factor IIB signature 19 39 6.8E-63 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 A0127_08500 9c2c54b1718ec8a506c771a89aefa646 300 PRINTS PR00685 Transcription initiation factor IIB signature 245 261 6.8E-63 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 A0127_08500 9c2c54b1718ec8a506c771a89aefa646 300 PRINTS PR00685 Transcription initiation factor IIB signature 54 75 6.8E-63 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 A0127_08500 9c2c54b1718ec8a506c771a89aefa646 300 PRINTS PR00685 Transcription initiation factor IIB signature 182 197 6.8E-63 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 A0127_08500 9c2c54b1718ec8a506c771a89aefa646 300 PRINTS PR00685 Transcription initiation factor IIB signature 211 229 6.8E-63 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 A0127_08500 9c2c54b1718ec8a506c771a89aefa646 300 PRINTS PR00685 Transcription initiation factor IIB signature 156 175 6.8E-63 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 A0127_08500 9c2c54b1718ec8a506c771a89aefa646 300 PRINTS PR00685 Transcription initiation factor IIB signature 41 54 6.8E-63 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 A0127_08500 9c2c54b1718ec8a506c771a89aefa646 300 PRINTS PR00685 Transcription initiation factor IIB signature 277 291 6.8E-63 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 A0127_08500 9c2c54b1718ec8a506c771a89aefa646 300 SUPERFAMILY SSF57783 4 50 2.95E-17 T 23-10-2018 A0127_08500 9c2c54b1718ec8a506c771a89aefa646 300 Pfam PF08271 TFIIB zinc-binding 6 47 2.2E-19 T 23-10-2018 IPR013137 Zinc finger, TFIIB-type A0127_02835 0751e012a803bcd003220171b846a1a9 161 Gene3D G3DSA:3.90.190.10 16 161 1.3E-35 T 23-10-2018 IPR029021 Protein-tyrosine phosphatase-like A0127_02835 0751e012a803bcd003220171b846a1a9 161 SMART SM00195 15 157 9.1E-7 T 23-10-2018 IPR020422 Dual specificity protein phosphatase domain GO:0006470|GO:0008138 A0127_02835 0751e012a803bcd003220171b846a1a9 161 SMART SM00404 63 157 1.5E-4 T 23-10-2018 IPR003595 Protein-tyrosine phosphatase, catalytic A0127_02835 0751e012a803bcd003220171b846a1a9 161 PRINTS PR00700 Protein tyrosine phosphatase signature 125 140 3.0E-5 T 23-10-2018 IPR000242 PTP type protein phosphatase GO:0004725|GO:0006470 A0127_02835 0751e012a803bcd003220171b846a1a9 161 PRINTS PR00700 Protein tyrosine phosphatase signature 141 151 3.0E-5 T 23-10-2018 IPR000242 PTP type protein phosphatase GO:0004725|GO:0006470 A0127_02835 0751e012a803bcd003220171b846a1a9 161 PRINTS PR00700 Protein tyrosine phosphatase signature 99 117 3.0E-5 T 23-10-2018 IPR000242 PTP type protein phosphatase GO:0004725|GO:0006470 A0127_02835 0751e012a803bcd003220171b846a1a9 161 Pfam PF00782 Dual specificity phosphatase, catalytic domain 39 156 6.3E-18 T 23-10-2018 IPR000340 Dual specificity phosphatase, catalytic domain GO:0008138|GO:0016311 A0127_02835 0751e012a803bcd003220171b846a1a9 161 SUPERFAMILY SSF52799 38 159 1.5E-35 T 23-10-2018 IPR029021 Protein-tyrosine phosphatase-like A0127_02835 0751e012a803bcd003220171b846a1a9 161 ProSitePatterns PS00383 Tyrosine specific protein phosphatases active site. 102 112 - T 23-10-2018 IPR016130 Protein-tyrosine phosphatase, active site GO:0004725|GO:0016311 A0127_02990 6be0fa2f0988e9e90847953094566502 380 SUPERFAMILY SSF52440 1 133 4.03E-43 T 23-10-2018 IPR016185 Pre-ATP-grasp domain superfamily A0127_02990 6be0fa2f0988e9e90847953094566502 380 Gene3D G3DSA:3.30.1490.20 152 218 3.8E-94 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 A0127_02990 6be0fa2f0988e9e90847953094566502 380 Pfam PF06849 Protein of unknown function (DUF1246) 21 153 7.5E-45 T 23-10-2018 IPR010672 IMP biosynthesis enzyme PurP, N-terminal GO:0000287|GO:0005524|GO:0006188|GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 A0127_02990 6be0fa2f0988e9e90847953094566502 380 Gene3D G3DSA:3.40.50.20 1 121 4.0E-44 T 23-10-2018 A0127_02990 6be0fa2f0988e9e90847953094566502 380 PIRSF PIRSF004602 1 380 7.7E-146 T 23-10-2018 IPR023656 IMP biosynthesis enzyme PurP GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 A0127_02990 6be0fa2f0988e9e90847953094566502 380 Gene3D G3DSA:3.30.470.20 122 379 3.8E-94 T 23-10-2018 A0127_02990 6be0fa2f0988e9e90847953094566502 380 Pfam PF06973 Domain of unknown function (DUF1297) 189 380 1.6E-80 T 23-10-2018 IPR009720 IMP biosynthesis enzyme PurP, C-terminal GO:0000287|GO:0005524|GO:0006188|GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 A0127_02990 6be0fa2f0988e9e90847953094566502 380 SUPERFAMILY SSF56059 139 380 1.74E-76 T 23-10-2018 A0127_01650 99f099adaba2be077e97e7acc67528b9 412 Gene3D G3DSA:3.40.50.2300 140 326 5.6E-92 T 23-10-2018 A0127_01650 99f099adaba2be077e97e7acc67528b9 412 Gene3D G3DSA:3.40.50.2300 39 314 5.6E-92 T 23-10-2018 A0127_01650 99f099adaba2be077e97e7acc67528b9 412 SUPERFAMILY SSF53822 51 301 9.16E-12 T 23-10-2018 IPR028082 Periplasmic binding protein-like I A0127_01650 99f099adaba2be077e97e7acc67528b9 412 Pfam PF02608 ABC transporter substrate-binding protein PnrA-like 40 342 2.1E-56 T 23-10-2018 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 A0127_09310 1c548e67cc06c063fde94db19ccd6f2e 421 SUPERFAMILY SSF50249 2 60 6.28E-7 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A0127_09310 1c548e67cc06c063fde94db19ccd6f2e 421 Gene3D G3DSA:3.40.50.150 75 414 3.9E-95 T 23-10-2018 A0127_09310 1c548e67cc06c063fde94db19ccd6f2e 421 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 10 412 2.7E-68 T 23-10-2018 A0127_09310 1c548e67cc06c063fde94db19ccd6f2e 421 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 345 420 1.9E-13 T 23-10-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 A0127_09310 1c548e67cc06c063fde94db19ccd6f2e 421 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 351 380 - T 23-10-2018 IPR030390 RNA methyltransferase TrmA, active site A0127_09310 1c548e67cc06c063fde94db19ccd6f2e 421 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 402 412 - T 23-10-2018 IPR030391 RNA methyltransferase TrmA, conserved site A0127_09310 1c548e67cc06c063fde94db19ccd6f2e 421 Gene3D G3DSA:2.40.50.140 3 63 5.6E-12 T 23-10-2018 A0127_09310 1c548e67cc06c063fde94db19ccd6f2e 421 Gene3D G3DSA:3.40.1350.30 114 262 3.9E-95 T 23-10-2018 A0127_09310 1c548e67cc06c063fde94db19ccd6f2e 421 SUPERFAMILY SSF53335 62 419 6.06E-65 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A0127_09310 1c548e67cc06c063fde94db19ccd6f2e 421 Pfam PF02475 Met-10+ like-protein 277 335 9.6E-10 T 23-10-2018 IPR030382 SAM-dependent methyltransferase TRM5/TYW2-type Reactome: R-HSA-6782861 A0127_00195 5b6ac249cf2d61401b53915191ed73dc 215 Gene3D G3DSA:3.30.980.10 86 214 6.4E-44 T 23-10-2018 A0127_00195 5b6ac249cf2d61401b53915191ed73dc 215 Gene3D G3DSA:2.40.30.130 14 85 6.3E-33 T 23-10-2018 A0127_00195 5b6ac249cf2d61401b53915191ed73dc 215 SUPERFAMILY SSF50447 2 85 1.73E-21 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily A0127_00195 5b6ac249cf2d61401b53915191ed73dc 215 SUPERFAMILY SSF55186 86 212 3.53E-33 T 23-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 A0127_00195 5b6ac249cf2d61401b53915191ed73dc 215 SMART SM00863 167 210 1.5E-6 T 23-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 A0127_00195 5b6ac249cf2d61401b53915191ed73dc 215 Pfam PF01411 tRNA synthetases class II (A) 14 88 8.9E-13 T 23-10-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 A0127_00195 5b6ac249cf2d61401b53915191ed73dc 215 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 179 210 4.0E-7 T 23-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 A0127_00800 3a351bcc25ba32d64153ecf46e997dda 245 SUPERFAMILY SSF69796 3 198 6.15E-60 T 23-10-2018 IPR036098 Thymidylate synthase ThyX superfamily GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 A0127_00800 3a351bcc25ba32d64153ecf46e997dda 245 TIGRFAM TIGR02170 thyX: thymidylate synthase, flavin-dependent 7 198 1.5E-52 T 23-10-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 A0127_00800 3a351bcc25ba32d64153ecf46e997dda 245 Gene3D G3DSA:3.30.1360.170 1 203 8.7E-63 T 23-10-2018 A0127_00800 3a351bcc25ba32d64153ecf46e997dda 245 Hamap MF_01408 Flavin-dependent thymidylate synthase [thyX]. 5 219 30.458 T 23-10-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 A0127_00800 3a351bcc25ba32d64153ecf46e997dda 245 Pfam PF02511 Thymidylate synthase complementing protein 8 198 3.4E-62 T 23-10-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 A0127_10325 cfe78918544b39c6f5f3ae02252ba8cc 447 SMART SM00382 8 188 2.7 T 23-10-2018 IPR003593 AAA+ ATPase domain A0127_10325 cfe78918544b39c6f5f3ae02252ba8cc 447 SMART SM00382 243 405 0.45 T 23-10-2018 IPR003593 AAA+ ATPase domain A0127_10325 cfe78918544b39c6f5f3ae02252ba8cc 447 SUPERFAMILY SSF52540 221 441 4.43E-42 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_10325 cfe78918544b39c6f5f3ae02252ba8cc 447 PIRSF PIRSF039117 1 446 8.0E-114 T 23-10-2018 IPR030665 Circadian clock protein kinase KaiC KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1 A0127_10325 cfe78918544b39c6f5f3ae02252ba8cc 447 Gene3D G3DSA:3.40.50.300 1 215 2.1E-45 T 23-10-2018 A0127_10325 cfe78918544b39c6f5f3ae02252ba8cc 447 Gene3D G3DSA:3.40.50.300 216 445 2.2E-57 T 23-10-2018 A0127_10325 cfe78918544b39c6f5f3ae02252ba8cc 447 SUPERFAMILY SSF52540 2 210 1.04E-31 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_10325 cfe78918544b39c6f5f3ae02252ba8cc 447 Pfam PF06745 KaiC 1 210 4.5E-58 T 23-10-2018 IPR014774 KaiC-like domain A0127_10325 cfe78918544b39c6f5f3ae02252ba8cc 447 Pfam PF06745 KaiC 226 442 2.2E-41 T 23-10-2018 IPR014774 KaiC-like domain A0127_04045 523088410db672eb1b38776858d35e2d 548 Pfam PF04473 Transglutaminase-like domain 266 385 7.3E-38 T 23-10-2018 IPR007562 Transglutaminase-like domain A0127_04045 523088410db672eb1b38776858d35e2d 548 Gene3D G3DSA:3.10.620.30 246 377 5.5E-10 T 23-10-2018 A0127_04045 523088410db672eb1b38776858d35e2d 548 SUPERFAMILY SSF54001 253 380 5.72E-11 T 23-10-2018 IPR038765 Papain-like cysteine peptidase superfamily A0127_09795 4387982a7e85fd2f02cdb697ff880625 236 SUPERFAMILY SSF46785 151 198 9.11E-6 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A0127_09795 4387982a7e85fd2f02cdb697ff880625 236 Pfam PF12840 Helix-turn-helix domain 5 59 1.5E-8 T 23-10-2018 A0127_09795 4387982a7e85fd2f02cdb697ff880625 236 SMART SM00418 5 86 1.3E-9 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A0127_09795 4387982a7e85fd2f02cdb697ff880625 236 Gene3D G3DSA:1.10.10.10 164 232 4.2E-36 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A0127_09795 4387982a7e85fd2f02cdb697ff880625 236 Gene3D G3DSA:1.10.10.10 2 77 2.3E-20 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A0127_09795 4387982a7e85fd2f02cdb697ff880625 236 SUPERFAMILY SSF46785 4 150 3.71E-15 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A0127_05805 add78b240448834d276f2ab08077b25e 461 Gene3D G3DSA:3.20.20.80 27 363 4.5E-108 T 23-10-2018 A0127_05805 add78b240448834d276f2ab08077b25e 461 SMART SM00642 36 381 2.6E-28 T 23-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 A0127_05805 add78b240448834d276f2ab08077b25e 461 PIRSF PIRSF001021 2 461 7.4E-117 T 23-10-2018 IPR013776 Alpha-amylase, thermostable GO:0004553|GO:0005509|GO:0005975 KEGG: 00500+3.2.1.1 A0127_05805 add78b240448834d276f2ab08077b25e 461 SUPERFAMILY SSF51445 33 385 6.03E-71 T 23-10-2018 IPR017853 Glycoside hydrolase superfamily A0127_05805 add78b240448834d276f2ab08077b25e 461 Pfam PF09154 Domain of unknown function (DUF1939) 390 456 1.2E-20 T 23-10-2018 IPR015237 Alpha-amylase C-terminal, prokaryotic GO:0004553 A0127_05805 add78b240448834d276f2ab08077b25e 461 Gene3D G3DSA:2.60.40.1180 364 461 7.7E-48 T 23-10-2018 IPR013780 Glycosyl hydrolase, all-beta A0127_05805 add78b240448834d276f2ab08077b25e 461 PRINTS PR00110 Alpha-amylase signature 305 317 3.3E-5 T 23-10-2018 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 A0127_05805 add78b240448834d276f2ab08077b25e 461 PRINTS PR00110 Alpha-amylase signature 218 229 3.3E-5 T 23-10-2018 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 A0127_05805 add78b240448834d276f2ab08077b25e 461 PRINTS PR00110 Alpha-amylase signature 126 137 3.3E-5 T 23-10-2018 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 A0127_05805 add78b240448834d276f2ab08077b25e 461 SUPERFAMILY SSF51011 388 461 1.94E-36 T 23-10-2018 A0127_05805 add78b240448834d276f2ab08077b25e 461 Pfam PF00128 Alpha amylase, catalytic domain 56 321 1.1E-11 T 23-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 A0127_06450 4ea3fb05103ab36cd1b4f5d690fb2a7c 1746 Pfam PF03477 ATP cone domain 5 93 4.1E-21 T 23-10-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 A0127_06450 4ea3fb05103ab36cd1b4f5d690fb2a7c 1746 SUPERFAMILY SSF51294 302 756 3.53E-43 T 23-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A0127_06450 4ea3fb05103ab36cd1b4f5d690fb2a7c 1746 TIGRFAM TIGR02504 NrdJ_Z: ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent 1296 1616 3.0E-127 T 23-10-2018 IPR013344 Ribonucleotide reductase, adenosylcobalamin-dependent GO:0000166|GO:0004748|GO:0031419|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A0127_06450 4ea3fb05103ab36cd1b4f5d690fb2a7c 1746 Pfam PF02867 Ribonucleotide reductase, barrel domain 756 1607 4.8E-222 T 23-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A0127_06450 4ea3fb05103ab36cd1b4f5d690fb2a7c 1746 Gene3D G3DSA:2.170.16.10 322 752 1.1E-180 T 23-10-2018 A0127_06450 4ea3fb05103ab36cd1b4f5d690fb2a7c 1746 SUPERFAMILY SSF55608 430 527 5.1E-46 T 23-10-2018 IPR027434 Homing endonuclease A0127_06450 4ea3fb05103ab36cd1b4f5d690fb2a7c 1746 SUPERFAMILY SSF54786 637 715 8.24E-41 T 23-10-2018 A0127_06450 4ea3fb05103ab36cd1b4f5d690fb2a7c 1746 PRINTS PR00379 Intein signature 1291 1300 4.3E-27 T 23-10-2018 IPR006142 Intein GO:0016539 A0127_06450 4ea3fb05103ab36cd1b4f5d690fb2a7c 1746 PRINTS PR00379 Intein signature 1011 1024 4.3E-27 T 23-10-2018 IPR006142 Intein GO:0016539 A0127_06450 4ea3fb05103ab36cd1b4f5d690fb2a7c 1746 PRINTS PR00379 Intein signature 1154 1166 4.3E-27 T 23-10-2018 IPR006142 Intein GO:0016539 A0127_06450 4ea3fb05103ab36cd1b4f5d690fb2a7c 1746 PRINTS PR00379 Intein signature 1181 1196 4.3E-27 T 23-10-2018 IPR006142 Intein GO:0016539 A0127_06450 4ea3fb05103ab36cd1b4f5d690fb2a7c 1746 PRINTS PR00379 Intein signature 1273 1290 4.3E-27 T 23-10-2018 IPR006142 Intein GO:0016539 A0127_06450 4ea3fb05103ab36cd1b4f5d690fb2a7c 1746 PRINTS PR00379 Intein signature 1060 1072 4.3E-27 T 23-10-2018 IPR006142 Intein GO:0016539 A0127_06450 4ea3fb05103ab36cd1b4f5d690fb2a7c 1746 Gene3D G3DSA:3.30.160.90 640 715 1.1E-180 T 23-10-2018 A0127_06450 4ea3fb05103ab36cd1b4f5d690fb2a7c 1746 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 1276 1297 1.2E-8 T 23-10-2018 IPR030934 Intein C-terminal splicing region A0127_06450 4ea3fb05103ab36cd1b4f5d690fb2a7c 1746 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 732 756 1.2E-6 T 23-10-2018 IPR030934 Intein C-terminal splicing region A0127_06450 4ea3fb05103ab36cd1b4f5d690fb2a7c 1746 SUPERFAMILY SSF55608 528 633 1.64E-22 T 23-10-2018 IPR027434 Homing endonuclease A0127_06450 4ea3fb05103ab36cd1b4f5d690fb2a7c 1746 SUPERFAMILY SSF55608 1136 1249 3.61E-21 T 23-10-2018 IPR027434 Homing endonuclease A0127_06450 4ea3fb05103ab36cd1b4f5d690fb2a7c 1746 Pfam PF14890 Intein splicing domain 995 1296 4.4E-22 T 23-10-2018 A0127_06450 4ea3fb05103ab36cd1b4f5d690fb2a7c 1746 Pfam PF14890 Intein splicing domain 309 755 3.9E-46 T 23-10-2018 A0127_06450 4ea3fb05103ab36cd1b4f5d690fb2a7c 1746 Gene3D G3DSA:2.170.16.10 916 1056 6.6E-15 T 23-10-2018 A0127_06450 4ea3fb05103ab36cd1b4f5d690fb2a7c 1746 Pfam PF09062 PI-PfuI Endonuclease subdomain 430 527 1.9E-56 T 23-10-2018 IPR015147 PI-PfuI intein endonuclease, subdomain KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A0127_06450 4ea3fb05103ab36cd1b4f5d690fb2a7c 1746 SUPERFAMILY SSF51998 209 302 7.63E-7 T 23-10-2018 A0127_06450 4ea3fb05103ab36cd1b4f5d690fb2a7c 1746 TIGRFAM TIGR01445 intein_Nterm: intein N-terminal splicing region 302 404 2.9E-12 T 23-10-2018 IPR006141 Intein N-terminal splicing region GO:0016539 Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A0127_06450 4ea3fb05103ab36cd1b4f5d690fb2a7c 1746 TIGRFAM TIGR01445 intein_Nterm: intein N-terminal splicing region 915 1024 1.8E-18 T 23-10-2018 IPR006141 Intein N-terminal splicing region GO:0016539 Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A0127_06450 4ea3fb05103ab36cd1b4f5d690fb2a7c 1746 Gene3D G3DSA:3.10.28.10 526 639 1.1E-180 T 23-10-2018 IPR027434 Homing endonuclease A0127_06450 4ea3fb05103ab36cd1b4f5d690fb2a7c 1746 Gene3D G3DSA:3.10.28.10 439 525 1.1E-180 T 23-10-2018 IPR027434 Homing endonuclease A0127_06450 4ea3fb05103ab36cd1b4f5d690fb2a7c 1746 SMART SM00306 913 1044 2.5E-26 T 23-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A0127_06450 4ea3fb05103ab36cd1b4f5d690fb2a7c 1746 SMART SM00306 300 429 3.2E-20 T 23-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A0127_06450 4ea3fb05103ab36cd1b4f5d690fb2a7c 1746 SMART SM00305 1257 1302 1.3E-10 T 23-10-2018 IPR003586 Hint domain C-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A0127_06450 4ea3fb05103ab36cd1b4f5d690fb2a7c 1746 SMART SM00305 715 761 2.0E-6 T 23-10-2018 IPR003586 Hint domain C-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A0127_06450 4ea3fb05103ab36cd1b4f5d690fb2a7c 1746 Gene3D G3DSA:3.20.70.20 753 915 3.3E-54 T 23-10-2018 A0127_06450 4ea3fb05103ab36cd1b4f5d690fb2a7c 1746 Gene3D G3DSA:3.20.70.20 1275 1622 4.1E-118 T 23-10-2018 A0127_06450 4ea3fb05103ab36cd1b4f5d690fb2a7c 1746 Pfam PF09061 Stirrup 637 715 5.0E-49 T 23-10-2018 IPR015146 Ribonucleotide reductase, stirrup GO:0016788 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A0127_06450 4ea3fb05103ab36cd1b4f5d690fb2a7c 1746 SUPERFAMILY SSF48168 9 155 1.46E-12 T 23-10-2018 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A0127_06450 4ea3fb05103ab36cd1b4f5d690fb2a7c 1746 SUPERFAMILY SSF51998 755 1618 7.55E-136 T 23-10-2018 A0127_06450 4ea3fb05103ab36cd1b4f5d690fb2a7c 1746 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 113 268 8.6E-28 T 23-10-2018 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A0127_06450 4ea3fb05103ab36cd1b4f5d690fb2a7c 1746 SUPERFAMILY SSF51294 914 1296 5.49E-42 T 23-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A0127_06450 4ea3fb05103ab36cd1b4f5d690fb2a7c 1746 Pfam PF14528 LAGLIDADG-like domain 1153 1242 6.6E-22 T 23-10-2018 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 A0127_06450 4ea3fb05103ab36cd1b4f5d690fb2a7c 1746 Pfam PF14528 LAGLIDADG-like domain 542 615 2.9E-12 T 23-10-2018 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 A0127_06450 4ea3fb05103ab36cd1b4f5d690fb2a7c 1746 Gene3D G3DSA:3.20.70.20 71 161 1.2E-5 T 23-10-2018 A0127_06450 4ea3fb05103ab36cd1b4f5d690fb2a7c 1746 Gene3D G3DSA:3.20.70.20 164 303 3.7E-20 T 23-10-2018 A0127_06450 4ea3fb05103ab36cd1b4f5d690fb2a7c 1746 Gene3D G3DSA:3.10.28.10 1057 1213 1.3E-32 T 23-10-2018 IPR027434 Homing endonuclease A0127_00310 c078365871b46ce01bad993f881031fe 348 Pfam PF01321 Creatinase/Prolidase N-terminal domain 2 124 7.9E-23 T 23-10-2018 IPR000587 Creatinase, N-terminal GO:0016787 A0127_00310 c078365871b46ce01bad993f881031fe 348 SUPERFAMILY SSF55920 123 347 7.07E-87 T 23-10-2018 IPR036005 Creatinase/aminopeptidase-like A0127_00310 c078365871b46ce01bad993f881031fe 348 SUPERFAMILY SSF53092 6 124 1.06E-25 T 23-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal A0127_00310 c078365871b46ce01bad993f881031fe 348 Gene3D G3DSA:3.40.350.10 1 122 2.4E-29 T 23-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal A0127_00310 c078365871b46ce01bad993f881031fe 348 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 280 292 - T 23-10-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site A0127_00310 c078365871b46ce01bad993f881031fe 348 Pfam PF00557 Metallopeptidase family M24 132 334 5.0E-71 T 23-10-2018 IPR000994 Peptidase M24 A0127_00310 c078365871b46ce01bad993f881031fe 348 Gene3D G3DSA:3.90.230.10 123 348 2.1E-90 T 23-10-2018 A0127_06840 ec23fb2adc347b41a9488cb57391836a 482 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 443 450 8.9E-17 T 23-10-2018 A0127_06840 ec23fb2adc347b41a9488cb57391836a 482 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 160 182 8.9E-17 T 23-10-2018 A0127_06840 ec23fb2adc347b41a9488cb57391836a 482 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 402 416 8.9E-17 T 23-10-2018 A0127_06840 ec23fb2adc347b41a9488cb57391836a 482 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 299 324 8.9E-17 T 23-10-2018 A0127_06840 ec23fb2adc347b41a9488cb57391836a 482 SUPERFAMILY SSF46548 10 169 5.75E-31 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 A0127_06840 ec23fb2adc347b41a9488cb57391836a 482 SUPERFAMILY SSF51971 160 409 1.65E-70 T 23-10-2018 A0127_06840 ec23fb2adc347b41a9488cb57391836a 482 TIGRFAM TIGR01316 gltA: glutamate synthase (NADPH), homotetrameric 19 474 6.2E-227 T 23-10-2018 IPR006004 Glutamate synthase (NADPH), homotetrameric KEGG: 00195+1.18.1.2|MetaCyc: PWY-101 A0127_06840 ec23fb2adc347b41a9488cb57391836a 482 Gene3D G3DSA:1.10.1060.10 11 153 4.2E-39 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 A0127_06840 ec23fb2adc347b41a9488cb57391836a 482 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 23 141 3.2E-39 T 23-10-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 A0127_06840 ec23fb2adc347b41a9488cb57391836a 482 Gene3D G3DSA:3.50.50.60 270 409 8.1E-46 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A0127_06840 ec23fb2adc347b41a9488cb57391836a 482 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 161 180 2.9E-23 T 23-10-2018 A0127_06840 ec23fb2adc347b41a9488cb57391836a 482 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 299 317 2.9E-23 T 23-10-2018 A0127_06840 ec23fb2adc347b41a9488cb57391836a 482 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 401 417 2.9E-23 T 23-10-2018 A0127_06840 ec23fb2adc347b41a9488cb57391836a 482 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 244 262 2.9E-23 T 23-10-2018 A0127_06840 ec23fb2adc347b41a9488cb57391836a 482 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 428 450 2.9E-23 T 23-10-2018 A0127_06840 ec23fb2adc347b41a9488cb57391836a 482 Gene3D G3DSA:3.40.50.720 157 269 7.2E-26 T 23-10-2018 A0127_06840 ec23fb2adc347b41a9488cb57391836a 482 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 160 459 2.7E-42 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A0127_05170 010bc3b3b662f7582e99115e1759cdb4 291 Pfam PF13649 Methyltransferase domain 132 233 3.4E-9 T 23-10-2018 A0127_05170 010bc3b3b662f7582e99115e1759cdb4 291 SUPERFAMILY SSF53335 92 264 6.58E-34 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A0127_05170 010bc3b3b662f7582e99115e1759cdb4 291 Gene3D G3DSA:3.40.50.150 120 287 4.0E-25 T 23-10-2018 A0127_01705 a6aec03c37f8311a8fe1344b2347ffc2 53 PRINTS PR00163 Rubredoxin signature 3 19 3.1E-12 T 23-10-2018 IPR024935 Rubredoxin domain GO:0005506 A0127_01705 a6aec03c37f8311a8fe1344b2347ffc2 53 PRINTS PR00163 Rubredoxin signature 33 49 3.1E-12 T 23-10-2018 IPR024935 Rubredoxin domain GO:0005506 A0127_01705 a6aec03c37f8311a8fe1344b2347ffc2 53 Gene3D G3DSA:2.20.28.10 2 53 2.1E-30 T 23-10-2018 A0127_01705 a6aec03c37f8311a8fe1344b2347ffc2 53 Pfam PF00301 Rubredoxin 3 49 3.9E-26 T 23-10-2018 IPR024935 Rubredoxin domain GO:0005506 A0127_01705 a6aec03c37f8311a8fe1344b2347ffc2 53 PIRSF PIRSF000071 1 53 1.7E-29 T 23-10-2018 IPR024922 Rubredoxin GO:0005506|GO:0009055 A0127_01705 a6aec03c37f8311a8fe1344b2347ffc2 53 ProSitePatterns PS00202 Rubredoxin signature. 33 43 - T 23-10-2018 IPR018527 Rubredoxin, iron-binding site GO:0046872 A0127_01705 a6aec03c37f8311a8fe1344b2347ffc2 53 SUPERFAMILY SSF57802 1 53 2.02E-25 T 23-10-2018 A0127_02470 491f2efb71cb28582abca81ca8bbc95f 195 Pfam PF02568 Thiamine biosynthesis protein (ThiI) 2 191 5.1E-56 T 23-10-2018 IPR020536 Thil, AANH domain GO:0004810 KEGG: 00730+2.8.1.4 A0127_02470 491f2efb71cb28582abca81ca8bbc95f 195 SUPERFAMILY SSF52402 2 156 2.96E-39 T 23-10-2018 A0127_02470 491f2efb71cb28582abca81ca8bbc95f 195 Gene3D G3DSA:3.40.50.620 1 194 1.9E-57 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A0127_06805 be80f6d736a0a2ee58a14a7afc59a7c5 662 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 381 391 - T 23-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site A0127_06805 be80f6d736a0a2ee58a14a7afc59a7c5 662 PIRSF PIRSF037907 1 662 0.0 T 23-10-2018 IPR017319 Subtilisin-like serine protease TK1689-type A0127_06805 be80f6d736a0a2ee58a14a7afc59a7c5 662 Pfam PF04151 Bacterial pre-peptidase C-terminal domain 576 643 1.2E-9 T 23-10-2018 IPR007280 Peptidase, C-terminal, archaeal/bacterial A0127_06805 be80f6d736a0a2ee58a14a7afc59a7c5 662 SUPERFAMILY SSF52743 151 441 4.19E-92 T 23-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 A0127_06805 be80f6d736a0a2ee58a14a7afc59a7c5 662 Gene3D G3DSA:2.60.120.380 446 546 1.5E-23 T 23-10-2018 A0127_06805 be80f6d736a0a2ee58a14a7afc59a7c5 662 Gene3D G3DSA:2.60.120.380 563 660 6.1E-16 T 23-10-2018 A0127_06805 be80f6d736a0a2ee58a14a7afc59a7c5 662 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 203 213 - T 23-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site A0127_06805 be80f6d736a0a2ee58a14a7afc59a7c5 662 SUPERFAMILY SSF49785 452 528 1.36E-6 T 23-10-2018 IPR008979 Galactose-binding-like domain superfamily A0127_06805 be80f6d736a0a2ee58a14a7afc59a7c5 662 Pfam PF00082 Subtilase family 161 432 2.1E-65 T 23-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A0127_06805 be80f6d736a0a2ee58a14a7afc59a7c5 662 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 166 177 - T 23-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site A0127_06805 be80f6d736a0a2ee58a14a7afc59a7c5 662 PRINTS PR00723 Subtilisin serine protease family (S8) signature 161 180 5.2E-22 T 23-10-2018 IPR015500 Peptidase S8, subtilisin-related A0127_06805 be80f6d736a0a2ee58a14a7afc59a7c5 662 PRINTS PR00723 Subtilisin serine protease family (S8) signature 380 396 5.2E-22 T 23-10-2018 IPR015500 Peptidase S8, subtilisin-related A0127_06805 be80f6d736a0a2ee58a14a7afc59a7c5 662 PRINTS PR00723 Subtilisin serine protease family (S8) signature 199 212 5.2E-22 T 23-10-2018 IPR015500 Peptidase S8, subtilisin-related A0127_06805 be80f6d736a0a2ee58a14a7afc59a7c5 662 Gene3D G3DSA:3.40.50.200 132 444 6.3E-140 T 23-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 A0127_06805 be80f6d736a0a2ee58a14a7afc59a7c5 662 Gene3D G3DSA:3.30.70.80 39 131 8.3E-57 T 23-10-2018 IPR037045 Peptidase S8 propeptide/proteinase inhibitor I9 superfamily Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 A0127_00955 77ef9f6e602c00fac396f61aaa237247 271 SUPERFAMILY SSF100950 12 121 1.15E-6 T 23-10-2018 IPR037171 NagB/RpiA transferase-like A0127_04360 7d78198f3dcd34461182211905ddcbea 308 PRINTS PR00101 Aspartate carbamoyltransferase signature 80 89 1.3E-38 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A0127_04360 7d78198f3dcd34461182211905ddcbea 308 PRINTS PR00101 Aspartate carbamoyltransferase signature 225 234 1.3E-38 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A0127_04360 7d78198f3dcd34461182211905ddcbea 308 PRINTS PR00101 Aspartate carbamoyltransferase signature 134 151 1.3E-38 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A0127_04360 7d78198f3dcd34461182211905ddcbea 308 PRINTS PR00101 Aspartate carbamoyltransferase signature 264 269 1.3E-38 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A0127_04360 7d78198f3dcd34461182211905ddcbea 308 PRINTS PR00101 Aspartate carbamoyltransferase signature 286 300 1.3E-38 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A0127_04360 7d78198f3dcd34461182211905ddcbea 308 PRINTS PR00101 Aspartate carbamoyltransferase signature 41 63 1.3E-38 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A0127_04360 7d78198f3dcd34461182211905ddcbea 308 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 6 304 2.7E-132 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A0127_04360 7d78198f3dcd34461182211905ddcbea 308 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 51 58 - T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A0127_04360 7d78198f3dcd34461182211905ddcbea 308 Gene3D G3DSA:3.40.50.1370 7 301 1.9E-124 T 23-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 A0127_04360 7d78198f3dcd34461182211905ddcbea 308 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 154 302 3.8E-30 T 23-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 A0127_04360 7d78198f3dcd34461182211905ddcbea 308 SUPERFAMILY SSF53671 2 306 1.44E-102 T 23-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 A0127_04360 7d78198f3dcd34461182211905ddcbea 308 Gene3D G3DSA:3.40.50.1370 135 292 1.9E-124 T 23-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 A0127_04360 7d78198f3dcd34461182211905ddcbea 308 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 270 293 4.3E-23 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A0127_04360 7d78198f3dcd34461182211905ddcbea 308 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 51 70 4.3E-23 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A0127_04360 7d78198f3dcd34461182211905ddcbea 308 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 260 269 4.3E-23 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A0127_04360 7d78198f3dcd34461182211905ddcbea 308 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 135 146 4.3E-23 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A0127_04360 7d78198f3dcd34461182211905ddcbea 308 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 5 307 39.402 T 23-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A0127_04360 7d78198f3dcd34461182211905ddcbea 308 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 6 147 3.9E-49 T 23-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 A0127_01135 2b78e369b677ea355c6cda4777026c09 347 Gene3D G3DSA:3.40.50.1970 1 156 4.7E-35 T 23-10-2018 A0127_01135 2b78e369b677ea355c6cda4777026c09 347 Pfam PF13685 Iron-containing alcohol dehydrogenase 13 269 2.2E-70 T 23-10-2018 IPR032837 Glycerol-1-phosphate dehydrogenase KEGG: 00564+1.1.1.261|MetaCyc: PWY-6349 A0127_01135 2b78e369b677ea355c6cda4777026c09 347 Gene3D G3DSA:1.20.1090.10 157 346 1.2E-66 T 23-10-2018 A0127_01135 2b78e369b677ea355c6cda4777026c09 347 Hamap MF_00497_A Glycerol-1-phosphate dehydrogenase [NAD(P)+] [egsA]. 3 347 45.983 T 23-10-2018 IPR023002 Glycerol-1-phosphate dehydrogenase, archaea GO:0050492|GO:0055114 KEGG: 00564+1.1.1.261|MetaCyc: PWY-6349 A0127_01135 2b78e369b677ea355c6cda4777026c09 347 PIRSF PIRSF000112 1 344 5.8E-67 T 23-10-2018 IPR016205 Glycerol dehydrogenase GO:0016614|GO:0046872|GO:0055114 KEGG: 00564+1.1.1.261|MetaCyc: PWY-6349 A0127_01135 2b78e369b677ea355c6cda4777026c09 347 SUPERFAMILY SSF56796 3 340 8.37E-73 T 23-10-2018 A0127_06480 2f2b9222064ddc49408060b17a9ac58f 306 SUPERFAMILY SSF52540 3 276 1.24E-45 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_06480 2f2b9222064ddc49408060b17a9ac58f 306 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 33 163 5.1E-60 T 23-10-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 A0127_06480 2f2b9222064ddc49408060b17a9ac58f 306 PIRSF PIRSF002849 1 306 6.2E-125 T 23-10-2018 A0127_06480 2f2b9222064ddc49408060b17a9ac58f 306 SMART SM00382 30 171 0.0083 T 23-10-2018 IPR003593 AAA+ ATPase domain A0127_06480 2f2b9222064ddc49408060b17a9ac58f 306 Gene3D G3DSA:1.10.8.300 193 301 3.7E-32 T 23-10-2018 A0127_06480 2f2b9222064ddc49408060b17a9ac58f 306 Gene3D G3DSA:3.40.50.300 14 180 7.6E-46 T 23-10-2018 A0127_04645 aed4ff806e90e3163f5b1b2fa06fbab5 410 SUPERFAMILY SSF52540 4 209 2.06E-54 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_04645 aed4ff806e90e3163f5b1b2fa06fbab5 410 PRINTS PR00315 GTP-binding elongation factor signature 13 26 4.1E-14 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A0127_04645 aed4ff806e90e3163f5b1b2fa06fbab5 410 PRINTS PR00315 GTP-binding elongation factor signature 140 149 4.1E-14 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A0127_04645 aed4ff806e90e3163f5b1b2fa06fbab5 410 PRINTS PR00315 GTP-binding elongation factor signature 103 114 4.1E-14 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A0127_04645 aed4ff806e90e3163f5b1b2fa06fbab5 410 PRINTS PR00315 GTP-binding elongation factor signature 87 97 4.1E-14 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A0127_04645 aed4ff806e90e3163f5b1b2fa06fbab5 410 Gene3D G3DSA:2.40.30.10 319 410 1.9E-34 T 23-10-2018 A0127_04645 aed4ff806e90e3163f5b1b2fa06fbab5 410 Pfam PF00009 Elongation factor Tu GTP binding domain 12 199 8.5E-37 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A0127_04645 aed4ff806e90e3163f5b1b2fa06fbab5 410 TIGRFAM TIGR03680 eif2g_arch: translation initiation factor 2, gamma subunit 8 409 3.9E-207 T 23-10-2018 IPR022424 Translation initiation factor 2, gamma subunit A0127_04645 aed4ff806e90e3163f5b1b2fa06fbab5 410 Pfam PF03144 Elongation factor Tu domain 2 231 311 1.1E-10 T 23-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 A0127_04645 aed4ff806e90e3163f5b1b2fa06fbab5 410 Hamap MF_00119 Translation initiation factor 2 subunit gamma [eif2g]. 4 409 61.6 T 23-10-2018 IPR022424 Translation initiation factor 2, gamma subunit A0127_04645 aed4ff806e90e3163f5b1b2fa06fbab5 410 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 10 193 3.4E-18 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A0127_04645 aed4ff806e90e3163f5b1b2fa06fbab5 410 SUPERFAMILY SSF50465 317 409 2.63E-33 T 23-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal A0127_04645 aed4ff806e90e3163f5b1b2fa06fbab5 410 Gene3D G3DSA:3.40.50.300 3 203 6.7E-70 T 23-10-2018 A0127_04645 aed4ff806e90e3163f5b1b2fa06fbab5 410 Pfam PF09173 Initiation factor eIF2 gamma, C terminal 324 408 2.1E-31 T 23-10-2018 IPR015256 Translation initiation factor 2, gamma subunit, C-terminal A0127_04645 aed4ff806e90e3163f5b1b2fa06fbab5 410 SUPERFAMILY SSF50447 203 316 1.12E-38 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily A0127_04645 aed4ff806e90e3163f5b1b2fa06fbab5 410 Gene3D G3DSA:2.40.30.10 204 318 8.0E-47 T 23-10-2018 A0127_07865 d60aebabe016246395ad3fc6bd441c33 343 SUPERFAMILY SSF48576 4 342 1.73E-96 T 23-10-2018 IPR008949 Isoprenoid synthase domain superfamily A0127_07865 d60aebabe016246395ad3fc6bd441c33 343 Gene3D G3DSA:1.10.600.10 1 343 2.9E-133 T 23-10-2018 IPR008949 Isoprenoid synthase domain superfamily A0127_07865 d60aebabe016246395ad3fc6bd441c33 343 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 83 97 - T 23-10-2018 IPR033749 Polyprenyl synthetase, conserved site A0127_07865 d60aebabe016246395ad3fc6bd441c33 343 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 210 222 - T 23-10-2018 IPR033749 Polyprenyl synthetase, conserved site A0127_07865 d60aebabe016246395ad3fc6bd441c33 343 Pfam PF00348 Polyprenyl synthetase 34 269 5.1E-70 T 23-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 A0127_03215 3625c2d69604f9ac30ad0a1e1cd44b13 388 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 106 124 3.7E-28 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A0127_03215 3625c2d69604f9ac30ad0a1e1cd44b13 388 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 150 168 3.7E-28 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A0127_03215 3625c2d69604f9ac30ad0a1e1cd44b13 388 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 85 105 3.7E-28 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A0127_03215 3625c2d69604f9ac30ad0a1e1cd44b13 388 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 133 148 3.7E-28 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A0127_03215 3625c2d69604f9ac30ad0a1e1cd44b13 388 Gene3D G3DSA:3.10.20.30 312 388 2.3E-29 T 23-10-2018 IPR012675 Beta-grasp domain superfamily A0127_03215 3625c2d69604f9ac30ad0a1e1cd44b13 388 Pfam PF16897 C-terminal region of MMR_HSR1 domain 206 310 5.1E-19 T 23-10-2018 IPR031662 GTP binding protein, second domain A0127_03215 3625c2d69604f9ac30ad0a1e1cd44b13 388 SUPERFAMILY SSF81271 309 386 5.76E-19 T 23-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 A0127_03215 3625c2d69604f9ac30ad0a1e1cd44b13 388 Pfam PF01926 50S ribosome-binding GTPase 84 186 7.4E-22 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A0127_03215 3625c2d69604f9ac30ad0a1e1cd44b13 388 Pfam PF02824 TGS domain 315 386 4.5E-24 T 23-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 A0127_03215 3625c2d69604f9ac30ad0a1e1cd44b13 388 SUPERFAMILY SSF52540 84 323 1.19E-51 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_03215 3625c2d69604f9ac30ad0a1e1cd44b13 388 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 83 190 1.4E-13 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A0127_02710 4e7b3ee6f596d373036132e4bb5188c0 732 Pfam PF14492 Elongation Factor G, domain II 387 459 5.3E-27 T 23-10-2018 A0127_02710 4e7b3ee6f596d373036132e4bb5188c0 732 Gene3D G3DSA:3.30.230.10 472 720 7.9E-76 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A0127_02710 4e7b3ee6f596d373036132e4bb5188c0 732 SUPERFAMILY SSF54980 388 463 5.76E-24 T 23-10-2018 IPR035647 EF-G domain III/V-like A0127_02710 4e7b3ee6f596d373036132e4bb5188c0 732 Pfam PF03764 Elongation factor G, domain IV 513 619 4.0E-27 T 23-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 A0127_02710 4e7b3ee6f596d373036132e4bb5188c0 732 Pfam PF00009 Elongation factor Tu GTP binding domain 20 257 2.4E-65 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A0127_02710 4e7b3ee6f596d373036132e4bb5188c0 732 Hamap MF_00054_A Elongation factor G [fusA]. 2 725 44.083 T 23-10-2018 IPR004543 Translation elongation factor EFG/EF2, archaeal GO:0003746|GO:0005525|GO:0005737|GO:0006414 A0127_02710 4e7b3ee6f596d373036132e4bb5188c0 732 SMART SM00838 621 708 3.2E-44 T 23-10-2018 IPR000640 Elongation factor EFG, domain V-like A0127_02710 4e7b3ee6f596d373036132e4bb5188c0 732 SUPERFAMILY SSF50447 259 373 1.92E-33 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily A0127_02710 4e7b3ee6f596d373036132e4bb5188c0 732 SUPERFAMILY SSF52540 10 261 5.86E-69 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_02710 4e7b3ee6f596d373036132e4bb5188c0 732 SUPERFAMILY SSF54211 463 623 2.78E-49 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A0127_02710 4e7b3ee6f596d373036132e4bb5188c0 732 Gene3D G3DSA:2.40.30.10 259 386 3.2E-28 T 23-10-2018 A0127_02710 4e7b3ee6f596d373036132e4bb5188c0 732 Gene3D G3DSA:3.40.50.300 7 222 1.3E-72 T 23-10-2018 A0127_02710 4e7b3ee6f596d373036132e4bb5188c0 732 TIGRFAM TIGR00490 aEF-2: translation elongation factor aEF-2 3 720 0.0 T 23-10-2018 IPR004543 Translation elongation factor EFG/EF2, archaeal GO:0003746|GO:0005525|GO:0005737|GO:0006414 A0127_02710 4e7b3ee6f596d373036132e4bb5188c0 732 Gene3D G3DSA:3.30.70.870 388 465 1.4E-28 T 23-10-2018 A0127_02710 4e7b3ee6f596d373036132e4bb5188c0 732 Gene3D G3DSA:3.30.70.240 466 718 7.9E-76 T 23-10-2018 A0127_02710 4e7b3ee6f596d373036132e4bb5188c0 732 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 60 75 - T 23-10-2018 IPR031157 Tr-type G domain, conserved site A0127_02710 4e7b3ee6f596d373036132e4bb5188c0 732 PRINTS PR00315 GTP-binding elongation factor signature 143 152 6.6E-16 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A0127_02710 4e7b3ee6f596d373036132e4bb5188c0 732 PRINTS PR00315 GTP-binding elongation factor signature 67 75 6.6E-16 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A0127_02710 4e7b3ee6f596d373036132e4bb5188c0 732 PRINTS PR00315 GTP-binding elongation factor signature 107 118 6.6E-16 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A0127_02710 4e7b3ee6f596d373036132e4bb5188c0 732 PRINTS PR00315 GTP-binding elongation factor signature 23 36 6.6E-16 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A0127_02710 4e7b3ee6f596d373036132e4bb5188c0 732 PRINTS PR00315 GTP-binding elongation factor signature 91 101 6.6E-16 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A0127_02710 4e7b3ee6f596d373036132e4bb5188c0 732 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 21 154 1.6E-20 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A0127_02710 4e7b3ee6f596d373036132e4bb5188c0 732 SMART SM00889 505 619 1.2E-20 T 23-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 A0127_02710 4e7b3ee6f596d373036132e4bb5188c0 732 SUPERFAMILY SSF54980 624 718 2.34E-23 T 23-10-2018 IPR035647 EF-G domain III/V-like A0127_02710 4e7b3ee6f596d373036132e4bb5188c0 732 Pfam PF03144 Elongation factor Tu domain 2 306 372 1.6E-15 T 23-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 A0127_02710 4e7b3ee6f596d373036132e4bb5188c0 732 Pfam PF00679 Elongation factor G C-terminus 621 706 9.2E-24 T 23-10-2018 IPR000640 Elongation factor EFG, domain V-like A0127_10045 01e628af94919735816ee5525e083c3d 289 Pfam PF13588 Type I restriction enzyme R protein N terminus (HSDR_N) 25 119 1.2E-7 T 23-10-2018 IPR029464 Type I restriction enzyme R protein, N-terminal domain A0127_10045 01e628af94919735816ee5525e083c3d 289 Gene3D G3DSA:3.90.1570.30 3 139 1.5E-5 T 23-10-2018 A0127_01090 80b9fda9c24c0310d9a4c71d1174a5f3 239 Pfam PF00013 KH domain 143 190 3.8E-6 T 23-10-2018 IPR004088 K Homology domain, type 1 GO:0003723 A0127_01090 80b9fda9c24c0310d9a4c71d1174a5f3 239 Pfam PF00013 KH domain 40 87 1.7E-9 T 23-10-2018 IPR004088 K Homology domain, type 1 GO:0003723 A0127_01090 80b9fda9c24c0310d9a4c71d1174a5f3 239 Gene3D G3DSA:3.30.1370.10 36 118 4.3E-35 T 23-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 A0127_01090 80b9fda9c24c0310d9a4c71d1174a5f3 239 SUPERFAMILY SSF54791 40 115 6.28E-13 T 23-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 A0127_01090 80b9fda9c24c0310d9a4c71d1174a5f3 239 TIGRFAM TIGR03665 arCOG04150: arCOG04150 universal archaeal KH domain protein 42 215 6.0E-69 T 23-10-2018 IPR019964 KH domain protein, archaea A0127_01090 80b9fda9c24c0310d9a4c71d1174a5f3 239 Gene3D G3DSA:3.30.1370.10 119 224 4.7E-33 T 23-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 A0127_01090 80b9fda9c24c0310d9a4c71d1174a5f3 239 SMART SM00322 36 106 6.0E-10 T 23-10-2018 IPR004087 K Homology domain GO:0003676 A0127_01090 80b9fda9c24c0310d9a4c71d1174a5f3 239 SMART SM00322 127 194 8.9E-7 T 23-10-2018 IPR004087 K Homology domain GO:0003676 A0127_01090 80b9fda9c24c0310d9a4c71d1174a5f3 239 SUPERFAMILY SSF54791 128 205 4.53E-18 T 23-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 A0127_02060 f6b07c96558941494ed90ff9de8ee04a 110 ProSitePatterns PS01030 RNA polymerases M / 15 Kd subunits signature. 3 25 - T 23-10-2018 IPR019761 DNA-directed RNA polymerase M, 15kDa subunit, conserved site A0127_02060 f6b07c96558941494ed90ff9de8ee04a 110 SMART SM00661 2 56 9.8E-15 T 23-10-2018 IPR001529 DNA-directed RNA polymerase, M/15kDa subunit GO:0006351 A0127_02060 f6b07c96558941494ed90ff9de8ee04a 110 TIGRFAM TIGR01384 TFS_arch: transcription factor S 2 110 1.3E-38 T 23-10-2018 IPR006288 Transcription factor S GO:0006355 A0127_02060 f6b07c96558941494ed90ff9de8ee04a 110 Gene3D G3DSA:2.20.25.10 55 110 1.9E-26 T 23-10-2018 A0127_02060 f6b07c96558941494ed90ff9de8ee04a 110 Pfam PF01096 Transcription factor S-II (TFIIS) 70 107 4.4E-21 T 23-10-2018 IPR001222 Zinc finger, TFIIS-type GO:0003676|GO:0006351|GO:0008270 A0127_02060 f6b07c96558941494ed90ff9de8ee04a 110 SUPERFAMILY SSF57783 1 34 2.98E-6 T 23-10-2018 A0127_02060 f6b07c96558941494ed90ff9de8ee04a 110 ProSitePatterns PS00466 Zinc finger TFIIS-type signature. 71 106 - T 23-10-2018 IPR001222 Zinc finger, TFIIS-type GO:0003676|GO:0006351|GO:0008270 A0127_02060 f6b07c96558941494ed90ff9de8ee04a 110 SMART SM00440 69 108 8.0E-24 T 23-10-2018 IPR001222 Zinc finger, TFIIS-type GO:0003676|GO:0006351|GO:0008270 A0127_02060 f6b07c96558941494ed90ff9de8ee04a 110 SUPERFAMILY SSF57783 48 109 3.74E-22 T 23-10-2018 A0127_02060 f6b07c96558941494ed90ff9de8ee04a 110 Pfam PF02150 RNA polymerases M/15 Kd subunit 1 34 2.2E-16 T 23-10-2018 IPR001529 DNA-directed RNA polymerase, M/15kDa subunit GO:0006351 A0127_02060 f6b07c96558941494ed90ff9de8ee04a 110 PIRSF PIRSF005586 1 110 8.6E-38 T 23-10-2018 IPR012164 DNA-directed RNA polymerase subunit/transcription factor S GO:0006351 A0127_00500 4d914fb2ea148f8f0dc8a906d585d297 267 SUPERFAMILY SSF55120 1 230 2.59E-66 T 23-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 A0127_00500 4d914fb2ea148f8f0dc8a906d585d297 267 PIRSF PIRSF001430 1 243 2.9E-78 T 23-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 A0127_00500 4d914fb2ea148f8f0dc8a906d585d297 267 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 2 222 5.3E-55 T 23-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 A0127_00500 4d914fb2ea148f8f0dc8a906d585d297 267 Pfam PF01416 tRNA pseudouridine synthase 129 228 4.3E-23 T 23-10-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 A0127_00500 4d914fb2ea148f8f0dc8a906d585d297 267 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 1 227 31.592 T 23-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 A0127_00500 4d914fb2ea148f8f0dc8a906d585d297 267 Gene3D G3DSA:3.30.70.660 104 226 1.8E-28 T 23-10-2018 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0003723|GO:0009982 A0127_00500 4d914fb2ea148f8f0dc8a906d585d297 267 Gene3D G3DSA:3.30.70.580 1 103 2.4E-23 T 23-10-2018 A0127_00495 092fe85986500eea5598afb7fb07113f 461 Gene3D G3DSA:3.40.50.300 84 261 1.7E-35 T 23-10-2018 A0127_00495 092fe85986500eea5598afb7fb07113f 461 Gene3D G3DSA:3.40.50.300 273 456 4.0E-34 T 23-10-2018 A0127_00495 092fe85986500eea5598afb7fb07113f 461 SUPERFAMILY SSF52540 25 209 5.2E-17 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_00495 092fe85986500eea5598afb7fb07113f 461 SUPERFAMILY SSF52540 136 419 4.37E-36 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_00495 092fe85986500eea5598afb7fb07113f 461 Pfam PF00271 Helicase conserved C-terminal domain 304 404 1.9E-11 T 23-10-2018 IPR001650 Helicase, C-terminal A0127_00495 092fe85986500eea5598afb7fb07113f 461 SMART SM00487 91 272 5.7E-27 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A0127_00495 092fe85986500eea5598afb7fb07113f 461 SMART SM00490 328 406 7.9E-13 T 23-10-2018 IPR001650 Helicase, C-terminal A0127_00495 092fe85986500eea5598afb7fb07113f 461 Pfam PF04851 Type III restriction enzyme, res subunit 92 231 2.0E-17 T 23-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 A0127_06220 1bb5b92056e8e9b35a1fd70b175c22c1 249 Gene3D G3DSA:3.40.50.300 4 249 1.6E-71 T 23-10-2018 A0127_06220 1bb5b92056e8e9b35a1fd70b175c22c1 249 SUPERFAMILY SSF52540 7 244 1.78E-46 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_06220 1bb5b92056e8e9b35a1fd70b175c22c1 249 Pfam PF06745 KaiC 10 246 1.7E-76 T 23-10-2018 IPR014774 KaiC-like domain A0127_02610 17d694df0f3a7dea551a5ec726551288 323 Gene3D G3DSA:3.40.630.40 30 205 2.3E-63 T 23-10-2018 A0127_02610 17d694df0f3a7dea551a5ec726551288 323 SUPERFAMILY SSF53187 32 205 8.27E-62 T 23-10-2018 A0127_02610 17d694df0f3a7dea551a5ec726551288 323 SMART SM00646 91 200 1.9E-40 T 23-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 A0127_02610 17d694df0f3a7dea551a5ec726551288 323 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 34 200 4.0E-53 T 23-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 A0127_02945 dbd0bedd215591e0a1e8fe3d0935d792 670 SUPERFAMILY SSF50692 524 659 5.65E-36 T 23-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily A0127_02945 dbd0bedd215591e0a1e8fe3d0935d792 670 Gene3D G3DSA:2.20.25.90 2 49 3.9E-8 T 23-10-2018 A0127_02945 dbd0bedd215591e0a1e8fe3d0935d792 670 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 5 48 4.9E-8 T 23-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A0127_02945 dbd0bedd215591e0a1e8fe3d0935d792 670 Gene3D G3DSA:2.40.40.20 543 659 8.8E-33 T 23-10-2018 A0127_02945 dbd0bedd215591e0a1e8fe3d0935d792 670 SMART SM00926 1 49 2.0E-6 T 23-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A0127_02945 dbd0bedd215591e0a1e8fe3d0935d792 670 Gene3D G3DSA:3.40.228.10 129 326 6.9E-165 T 23-10-2018 A0127_02945 dbd0bedd215591e0a1e8fe3d0935d792 670 TIGRFAM TIGR01591 Fdh-alpha: formate dehydrogenase, alpha subunit 4 656 1.3E-260 T 23-10-2018 IPR006478 Formate dehydrogenase, alpha subunit GO:0008863|GO:0015942|GO:0055114 KEGG: 00630+1.17.1.9|KEGG: 00680+1.17.1.9|MetaCyc: PWY-1881|MetaCyc: PWY-5497|MetaCyc: PWY-6696|MetaCyc: PWY-7985 A0127_02945 dbd0bedd215591e0a1e8fe3d0935d792 670 Pfam PF00384 Molybdopterin oxidoreductase 52 471 1.1E-82 T 23-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A0127_02945 dbd0bedd215591e0a1e8fe3d0935d792 670 Pfam PF01568 Molydopterin dinucleotide binding domain 552 650 8.6E-20 T 23-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 A0127_02945 dbd0bedd215591e0a1e8fe3d0935d792 670 SUPERFAMILY SSF53706 2 554 2.75E-190 T 23-10-2018 A0127_02945 dbd0bedd215591e0a1e8fe3d0935d792 670 Gene3D G3DSA:3.40.50.740 58 516 6.9E-165 T 23-10-2018 A0127_01055 047234066ef480ca78d8c85bdffbc8dc 383 Gene3D G3DSA:3.40.50.150 41 236 1.5E-27 T 23-10-2018 A0127_01055 047234066ef480ca78d8c85bdffbc8dc 383 SUPERFAMILY SSF53335 58 198 4.84E-21 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A0127_01055 047234066ef480ca78d8c85bdffbc8dc 383 Pfam PF13847 Methyltransferase domain 86 169 2.1E-9 T 23-10-2018 IPR025714 Methyltransferase domain A0127_07025 5032ae87def85e8839dd0a1e78b7ca1a 236 ProSitePatterns PS01267 Uncharacterized protein family UPF0023 signature. 37 56 - T 23-10-2018 IPR018023 Ribosome maturation protein SBDS, conserved site A0127_07025 5032ae87def85e8839dd0a1e78b7ca1a 236 SUPERFAMILY SSF54980 157 228 1.56E-22 T 23-10-2018 IPR035647 EF-G domain III/V-like A0127_07025 5032ae87def85e8839dd0a1e78b7ca1a 236 Gene3D G3DSA:3.30.70.240 163 235 3.1E-29 T 23-10-2018 A0127_07025 5032ae87def85e8839dd0a1e78b7ca1a 236 Gene3D G3DSA:1.10.10.900 88 162 1.0E-29 T 23-10-2018 IPR037188 Ribosome maturation protein Sdo1/SBDS, central domain superfamily A0127_07025 5032ae87def85e8839dd0a1e78b7ca1a 236 SUPERFAMILY SSF89895 4 87 4.97E-26 T 23-10-2018 IPR036786 Ribosome maturation protein SBDS, N-terminal domain superfamily A0127_07025 5032ae87def85e8839dd0a1e78b7ca1a 236 Pfam PF01172 Shwachman-Bodian-Diamond syndrome (SBDS) protein 8 94 8.1E-26 T 23-10-2018 IPR019783 Ribosome maturation protein SBDS, N-terminal A0127_07025 5032ae87def85e8839dd0a1e78b7ca1a 236 Gene3D G3DSA:3.30.1250.10 8 87 3.1E-31 T 23-10-2018 IPR036786 Ribosome maturation protein SBDS, N-terminal domain superfamily A0127_07025 5032ae87def85e8839dd0a1e78b7ca1a 236 Pfam PF09377 SBDS protein C-terminal domain 101 213 3.2E-16 T 23-10-2018 IPR018978 Ribosome maturation protein SBDS, C-terminal GO:0042254 A0127_07025 5032ae87def85e8839dd0a1e78b7ca1a 236 SUPERFAMILY SSF109728 82 155 3.01E-24 T 23-10-2018 IPR037188 Ribosome maturation protein Sdo1/SBDS, central domain superfamily A0127_07025 5032ae87def85e8839dd0a1e78b7ca1a 236 TIGRFAM TIGR00291 RNA_SBDS: rRNA metabolism protein, SBDS family 3 231 5.2E-91 T 23-10-2018 IPR002140 Ribosome maturation protein Sdo1/SBDS GO:0042256 A0127_05120 d8eae4082cd7be49f8dffa0ce458ce50 398 PIRSF PIRSF006487 1 398 1.4E-105 T 23-10-2018 IPR028896 Aminomethyltransferase-like KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 A0127_05120 d8eae4082cd7be49f8dffa0ce458ce50 398 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 293 383 6.5E-25 T 23-10-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 A0127_05120 d8eae4082cd7be49f8dffa0ce458ce50 398 SUPERFAMILY SSF103025 2 308 2.83E-94 T 23-10-2018 A0127_05120 d8eae4082cd7be49f8dffa0ce458ce50 398 SUPERFAMILY SSF101790 300 392 1.96E-25 T 23-10-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal A0127_05120 d8eae4082cd7be49f8dffa0ce458ce50 398 Gene3D G3DSA:2.40.30.110 310 383 2.0E-30 T 23-10-2018 A0127_05120 d8eae4082cd7be49f8dffa0ce458ce50 398 Hamap MF_00259 Aminomethyltransferase [gcvT]. 1 389 43.489 T 23-10-2018 IPR022903 Glycine cleavage system T protein, bacteria GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 A0127_05120 d8eae4082cd7be49f8dffa0ce458ce50 398 Gene3D G3DSA:3.30.1360.120 8 255 6.0E-90 T 23-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 A0127_05120 d8eae4082cd7be49f8dffa0ce458ce50 398 Gene3D G3DSA:3.30.70.1400 52 143 6.0E-90 T 23-10-2018 A0127_05120 d8eae4082cd7be49f8dffa0ce458ce50 398 Gene3D G3DSA:4.10.1250.10 269 305 6.0E-10 T 23-10-2018 A0127_05120 d8eae4082cd7be49f8dffa0ce458ce50 398 Pfam PF01571 Aminomethyltransferase folate-binding domain 8 287 1.5E-96 T 23-10-2018 IPR006222 Aminomethyltransferase, folate-binding domain A0127_05120 d8eae4082cd7be49f8dffa0ce458ce50 398 TIGRFAM TIGR00528 gcvT: glycine cleavage system T protein 3 387 2.5E-93 T 23-10-2018 IPR006223 Glycine cleavage system T protein GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 A0127_02170 e7e21f4b820d8be9bec83fccf91608ac 86 Gene3D G3DSA:2.20.25.30 9 86 2.9E-31 T 23-10-2018 IPR011331 Ribosomal protein L37ae/L37e GO:0003735|GO:0005622|GO:0005840|GO:0006412 A0127_02170 e7e21f4b820d8be9bec83fccf91608ac 86 TIGRFAM TIGR00280 eL43_euk_arch: ribosomal protein eL43 1 80 1.6E-36 T 23-10-2018 IPR002674 Ribosomal protein L37ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 A0127_02170 e7e21f4b820d8be9bec83fccf91608ac 86 Hamap MF_00327 50S ribosomal protein L37Ae [rpl37ae]. 3 71 25.043 T 23-10-2018 IPR002674 Ribosomal protein L37ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 A0127_02170 e7e21f4b820d8be9bec83fccf91608ac 86 Pfam PF01780 Ribosomal L37ae protein family 3 82 2.8E-33 T 23-10-2018 IPR002674 Ribosomal protein L37ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 A0127_02170 e7e21f4b820d8be9bec83fccf91608ac 86 SUPERFAMILY SSF57829 10 80 2.69E-28 T 23-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 A0127_09690 a991187580a35f4cb3ff0f914f8f9634 456 SUPERFAMILY SSF53738 155 259 9.03E-31 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A0127_09690 a991187580a35f4cb3ff0f914f8f9634 456 SUPERFAMILY SSF53738 261 367 3.92E-26 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A0127_09690 a991187580a35f4cb3ff0f914f8f9634 456 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 261 370 2.2E-27 T 23-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A0127_09690 a991187580a35f4cb3ff0f914f8f9634 456 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 236 251 7.0E-18 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A0127_09690 a991187580a35f4cb3ff0f914f8f9634 456 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 208 221 7.0E-18 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A0127_09690 a991187580a35f4cb3ff0f914f8f9634 456 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 174 193 7.0E-18 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A0127_09690 a991187580a35f4cb3ff0f914f8f9634 456 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 94 108 7.0E-18 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A0127_09690 a991187580a35f4cb3ff0f914f8f9634 456 Gene3D G3DSA:3.40.120.10 1 152 7.6E-65 T 23-10-2018 A0127_09690 a991187580a35f4cb3ff0f914f8f9634 456 TIGRFAM TIGR03990 Arch_GlmM: phosphoglucosamine mutase 3 446 1.2E-180 T 23-10-2018 IPR024086 Phosphoglucosamine mutase, archaeal type GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A0127_09690 a991187580a35f4cb3ff0f914f8f9634 456 Gene3D G3DSA:3.40.120.10 169 358 8.0E-78 T 23-10-2018 A0127_09690 a991187580a35f4cb3ff0f914f8f9634 456 SUPERFAMILY SSF53738 2 145 5.49E-48 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A0127_09690 a991187580a35f4cb3ff0f914f8f9634 456 Gene3D G3DSA:3.40.120.10 257 365 8.0E-78 T 23-10-2018 A0127_09690 a991187580a35f4cb3ff0f914f8f9634 456 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 156 256 3.2E-30 T 23-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A0127_09690 a991187580a35f4cb3ff0f914f8f9634 456 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 379 443 6.1E-13 T 23-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A0127_09690 a991187580a35f4cb3ff0f914f8f9634 456 SUPERFAMILY SSF55957 358 455 3.27E-24 T 23-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A0127_09690 a991187580a35f4cb3ff0f914f8f9634 456 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 3 137 5.8E-48 T 23-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A0127_09690 a991187580a35f4cb3ff0f914f8f9634 456 Gene3D G3DSA:3.30.310.50 371 455 1.2E-32 T 23-10-2018 A0127_00845 53a2af6f275121371255bf5f6c673aa1 185 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 2.3E-10 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A0127_00845 53a2af6f275121371255bf5f6c673aa1 185 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 2.3E-10 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A0127_00845 53a2af6f275121371255bf5f6c673aa1 185 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 2.3E-10 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A0127_00845 53a2af6f275121371255bf5f6c673aa1 185 SUPERFAMILY SSF54909 61 130 1.88E-6 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel A0127_00845 53a2af6f275121371255bf5f6c673aa1 185 Pfam PF01037 Lrp/AsnC ligand binding domain 67 132 7.2E-7 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A0127_00845 53a2af6f275121371255bf5f6c673aa1 185 SMART SM00344 1 106 4.1E-15 T 23-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A0127_00845 53a2af6f275121371255bf5f6c673aa1 185 Pfam PF13404 AsnC-type helix-turn-helix domain 1 42 2.2E-11 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A0127_00845 53a2af6f275121371255bf5f6c673aa1 185 Gene3D G3DSA:3.30.70.920 54 137 5.5E-7 T 23-10-2018 A0127_00845 53a2af6f275121371255bf5f6c673aa1 185 Gene3D G3DSA:1.10.10.10 1 50 3.2E-13 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A0127_00845 53a2af6f275121371255bf5f6c673aa1 185 SUPERFAMILY SSF46785 1 65 2.11E-11 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A0127_03140 fc9c095812f7e1904dd3e66dc062cc17 184 PIRSF PIRSF006707 2 177 5.4E-49 T 23-10-2018 IPR026282 DNA-binding protein, MJ1563 type A0127_03140 fc9c095812f7e1904dd3e66dc062cc17 184 Pfam PF01047 MarR family 38 81 7.2E-7 T 23-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A0127_03140 fc9c095812f7e1904dd3e66dc062cc17 184 Gene3D G3DSA:1.10.10.10 1 87 7.5E-25 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A0127_03140 fc9c095812f7e1904dd3e66dc062cc17 184 SUPERFAMILY SSF46785 3 138 1.66E-23 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A0127_03140 fc9c095812f7e1904dd3e66dc062cc17 184 SMART SM00347 16 110 0.0019 T 23-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A0127_02940 149efaa2e878b2a10de05815868b4129 197 SUPERFAMILY SSF52317 2 195 1.0E-49 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A0127_02940 149efaa2e878b2a10de05815868b4129 197 PIRSF PIRSF005639 1 197 4.7E-69 T 23-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A0127_02940 149efaa2e878b2a10de05815868b4129 197 Gene3D G3DSA:3.40.50.880 1 197 5.7E-69 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A0127_02940 149efaa2e878b2a10de05815868b4129 197 Hamap MF_01615 Pyridoxal 5'-phosphate synthase subunit PdxT [pdxT]. 4 195 35.239 T 23-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A0127_02940 149efaa2e878b2a10de05815868b4129 197 TIGRFAM TIGR03800 PLP_synth_Pdx2: pyridoxal 5'-phosphate synthase, glutaminase subunit Pdx2 3 193 4.0E-75 T 23-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A0127_02940 149efaa2e878b2a10de05815868b4129 197 ProSitePatterns PS01236 PdxT/SNO family family signature. 47 57 - T 23-10-2018 IPR021196 PdxT/SNO family, conserved site KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A0127_02940 149efaa2e878b2a10de05815868b4129 197 Pfam PF01174 SNO glutamine amidotransferase family 6 196 7.4E-58 T 23-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A0127_01875 96547ec610e5cae82457384f0661ff9e 166 Pfam PF13412 Winged helix-turn-helix DNA-binding 5 51 1.8E-13 T 23-10-2018 A0127_01875 96547ec610e5cae82457384f0661ff9e 166 SUPERFAMILY SSF46785 4 62 1.12E-14 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A0127_01875 96547ec610e5cae82457384f0661ff9e 166 Gene3D G3DSA:3.30.70.920 58 148 1.4E-11 T 23-10-2018 A0127_01875 96547ec610e5cae82457384f0661ff9e 166 SMART SM00344 4 112 1.2E-28 T 23-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A0127_01875 96547ec610e5cae82457384f0661ff9e 166 Gene3D G3DSA:1.10.10.10 2 57 2.0E-18 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A0127_01875 96547ec610e5cae82457384f0661ff9e 166 ProSitePatterns PS00519 AsnC-type HTH domain signature. 22 48 - T 23-10-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site A0127_01875 96547ec610e5cae82457384f0661ff9e 166 Pfam PF01037 Lrp/AsnC ligand binding domain 78 134 1.8E-9 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A0127_01875 96547ec610e5cae82457384f0661ff9e 166 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 31 50 4.0E-14 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A0127_01875 96547ec610e5cae82457384f0661ff9e 166 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 4 20 4.0E-14 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A0127_01875 96547ec610e5cae82457384f0661ff9e 166 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 20 31 4.0E-14 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A0127_01875 96547ec610e5cae82457384f0661ff9e 166 SUPERFAMILY SSF54909 80 134 2.15E-7 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel A0127_10130 fc7131166c45dab3a41f7f3ed17f88ae 390 Gene3D G3DSA:3.40.50.1100 14 364 1.9E-105 T 23-10-2018 A0127_10130 fc7131166c45dab3a41f7f3ed17f88ae 390 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 16 357 7.7E-62 T 23-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme A0127_10130 fc7131166c45dab3a41f7f3ed17f88ae 390 SUPERFAMILY SSF53686 10 378 9.57E-90 T 23-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme A0127_10130 fc7131166c45dab3a41f7f3ed17f88ae 390 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 42 60 - T 23-10-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 A0127_10130 fc7131166c45dab3a41f7f3ed17f88ae 390 Gene3D G3DSA:3.40.50.1100 53 197 1.9E-105 T 23-10-2018 A0127_08660 f8e8e6a94922c2268c98002d297e91be 477 Pfam PF02272 DHHA1 domain 329 464 6.7E-22 T 23-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 A0127_08660 f8e8e6a94922c2268c98002d297e91be 477 Gene3D G3DSA:3.10.310.30 336 468 1.3E-9 T 23-10-2018 A0127_08660 f8e8e6a94922c2268c98002d297e91be 477 SUPERFAMILY SSF64182 7 470 1.31E-64 T 23-10-2018 IPR038763 DHH phosphoesterase superfamily A0127_08660 f8e8e6a94922c2268c98002d297e91be 477 Gene3D G3DSA:3.90.1640.30 2 219 5.8E-19 T 23-10-2018 A0127_03925 4601f522bb276b85cb6c768b0423ad64 444 TIGRFAM TIGR03326 rubisco_III: ribulose bisphosphate carboxylase, type III 11 438 4.5E-224 T 23-10-2018 IPR017712 Ribulose bisphosphate carboxylase, type III GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 A0127_03925 4601f522bb276b85cb6c768b0423ad64 444 SUPERFAMILY SSF54966 4 137 4.06E-40 T 23-10-2018 IPR036422 RuBisCO large subunit, N-terminal domain superfamily GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 A0127_03925 4601f522bb276b85cb6c768b0423ad64 444 SUPERFAMILY SSF51649 136 441 5.23E-107 T 23-10-2018 IPR036376 Ribulose bisphosphate carboxylase, large subunit, C-terminal domain superfamily GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 A0127_03925 4601f522bb276b85cb6c768b0423ad64 444 Gene3D G3DSA:3.20.20.110 137 438 2.6E-126 T 23-10-2018 IPR036376 Ribulose bisphosphate carboxylase, large subunit, C-terminal domain superfamily GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 A0127_03925 4601f522bb276b85cb6c768b0423ad64 444 Pfam PF02788 Ribulose bisphosphate carboxylase large chain, N-terminal domain 12 131 3.8E-46 T 23-10-2018 IPR017443 Ribulose bisphosphate carboxylase, large subunit, ferrodoxin-like N-terminal GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 A0127_03925 4601f522bb276b85cb6c768b0423ad64 444 Pfam PF00016 Ribulose bisphosphate carboxylase large chain, catalytic domain 142 438 1.3E-94 T 23-10-2018 IPR000685 Ribulose bisphosphate carboxylase, large subunit, C-terminal GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 A0127_03925 4601f522bb276b85cb6c768b0423ad64 444 Gene3D G3DSA:3.30.70.150 1 136 1.7E-47 T 23-10-2018 IPR036422 RuBisCO large subunit, N-terminal domain superfamily GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 A0127_03925 4601f522bb276b85cb6c768b0423ad64 444 Hamap MF_01133 Ribulose bisphosphate carboxylase [rbcL]. 10 439 52.692 T 23-10-2018 IPR017712 Ribulose bisphosphate carboxylase, type III GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 A0127_07450 9e070a2b141d31706023b76e4185c145 458 SUPERFAMILY SSF52540 3 236 2.92E-35 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_07450 9e070a2b141d31706023b76e4185c145 458 Pfam PF03008 Archaea bacterial proteins of unknown function 303 401 3.0E-31 T 23-10-2018 IPR004256 Domain of unknown function DUF234, DEXX-box ATPase C-terminal A0127_07450 9e070a2b141d31706023b76e4185c145 458 Pfam PF01637 ATPase domain predominantly from Archaea 5 182 3.9E-21 T 23-10-2018 IPR011579 ATPase domain GO:0005524 A0127_07450 9e070a2b141d31706023b76e4185c145 458 Gene3D G3DSA:3.40.50.300 2 165 1.2E-30 T 23-10-2018 A0127_07450 9e070a2b141d31706023b76e4185c145 458 SUPERFAMILY SSF46785 233 312 9.58E-7 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A0127_04595 e452279b3496ae0cad2781fc840a99f7 448 PRINTS PR01874 DNA repair protein radA signature 154 182 1.4E-9 T 23-10-2018 A0127_04595 e452279b3496ae0cad2781fc840a99f7 448 PRINTS PR01874 DNA repair protein radA signature 13 41 1.4E-9 T 23-10-2018 A0127_04595 e452279b3496ae0cad2781fc840a99f7 448 PRINTS PR01874 DNA repair protein radA signature 55 72 1.4E-9 T 23-10-2018 A0127_04595 e452279b3496ae0cad2781fc840a99f7 448 PIRSF PIRSF039117 1 448 1.6E-124 T 23-10-2018 IPR030665 Circadian clock protein kinase KaiC KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1 A0127_04595 e452279b3496ae0cad2781fc840a99f7 448 Gene3D G3DSA:3.40.50.300 226 448 3.4E-49 T 23-10-2018 A0127_04595 e452279b3496ae0cad2781fc840a99f7 448 Pfam PF06745 KaiC 239 447 3.7E-31 T 23-10-2018 IPR014774 KaiC-like domain A0127_04595 e452279b3496ae0cad2781fc840a99f7 448 Pfam PF06745 KaiC 4 222 2.4E-50 T 23-10-2018 IPR014774 KaiC-like domain A0127_04595 e452279b3496ae0cad2781fc840a99f7 448 SMART SM00382 255 405 8.4E-6 T 23-10-2018 IPR003593 AAA+ ATPase domain A0127_04595 e452279b3496ae0cad2781fc840a99f7 448 SMART SM00382 21 194 0.011 T 23-10-2018 IPR003593 AAA+ ATPase domain A0127_04595 e452279b3496ae0cad2781fc840a99f7 448 SUPERFAMILY SSF52540 237 447 1.18E-37 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_04595 e452279b3496ae0cad2781fc840a99f7 448 SUPERFAMILY SSF52540 2 225 4.0E-40 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_04595 e452279b3496ae0cad2781fc840a99f7 448 Gene3D G3DSA:3.40.50.300 1 225 4.9E-52 T 23-10-2018 A0127_09265 50d81cfe25e9be1bd22ccea3918b8e2b 396 Gene3D G3DSA:3.40.50.970 10 211 1.0E-76 T 23-10-2018 A0127_09265 50d81cfe25e9be1bd22ccea3918b8e2b 396 SUPERFAMILY SSF52518 23 277 8.83E-67 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold A0127_09265 50d81cfe25e9be1bd22ccea3918b8e2b 396 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 34 270 3.3E-75 T 23-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 A0127_09265 50d81cfe25e9be1bd22ccea3918b8e2b 396 SUPERFAMILY SSF52922 286 393 5.42E-23 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A0127_09265 50d81cfe25e9be1bd22ccea3918b8e2b 396 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 294 388 1.3E-18 T 23-10-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II A0127_09265 50d81cfe25e9be1bd22ccea3918b8e2b 396 Gene3D G3DSA:3.40.50.920 283 395 3.0E-22 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A0127_01285 ab506bbfcedfbf348587893dd6408f32 431 Hamap MF_00534 Asparagine--tRNA ligase [asnS]. 4 431 37.53 T 23-10-2018 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22 A0127_01285 ab506bbfcedfbf348587893dd6408f32 431 Gene3D G3DSA:2.40.50.140 1 101 5.2E-29 T 23-10-2018 A0127_01285 ab506bbfcedfbf348587893dd6408f32 431 SUPERFAMILY SSF50249 5 99 1.47E-24 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A0127_01285 ab506bbfcedfbf348587893dd6408f32 431 TIGRFAM TIGR00457 asnS: asparagine--tRNA ligase 14 430 3.0E-129 T 23-10-2018 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22 A0127_01285 ab506bbfcedfbf348587893dd6408f32 431 Pfam PF00152 tRNA synthetases class II (D, K and N) 111 425 3.4E-87 T 23-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 A0127_01285 ab506bbfcedfbf348587893dd6408f32 431 PRINTS PR01042 Aspartyl-tRNA synthetase signature 197 210 9.8E-15 T 23-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A0127_01285 ab506bbfcedfbf348587893dd6408f32 431 PRINTS PR01042 Aspartyl-tRNA synthetase signature 386 400 9.8E-15 T 23-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A0127_01285 ab506bbfcedfbf348587893dd6408f32 431 PRINTS PR01042 Aspartyl-tRNA synthetase signature 346 362 9.8E-15 T 23-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A0127_01285 ab506bbfcedfbf348587893dd6408f32 431 PRINTS PR01042 Aspartyl-tRNA synthetase signature 181 193 9.8E-15 T 23-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A0127_01285 ab506bbfcedfbf348587893dd6408f32 431 Pfam PF01336 OB-fold nucleic acid binding domain 19 97 2.9E-14 T 23-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 A0127_01285 ab506bbfcedfbf348587893dd6408f32 431 SUPERFAMILY SSF55681 111 426 1.58E-88 T 23-10-2018 A0127_01285 ab506bbfcedfbf348587893dd6408f32 431 Gene3D G3DSA:3.30.930.10 105 431 8.6E-117 T 23-10-2018 A0127_08075 ec166d6cd38bcb62d810d3986de71717 155 SUPERFAMILY SSF51283 1 153 1.19E-39 T 23-10-2018 IPR036157 dUTPase-like superfamily A0127_08075 ec166d6cd38bcb62d810d3986de71717 155 Hamap MF_00146 dCTP deaminase [dcd]. 1 153 27.27 T 23-10-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 A0127_08075 ec166d6cd38bcb62d810d3986de71717 155 Gene3D G3DSA:2.70.40.10 1 155 4.7E-42 T 23-10-2018 IPR036157 dUTPase-like superfamily A0127_08075 ec166d6cd38bcb62d810d3986de71717 155 Pfam PF00692 dUTPase 49 140 1.8E-12 T 23-10-2018 IPR029054 dUTPase-like A0127_08075 ec166d6cd38bcb62d810d3986de71717 155 TIGRFAM TIGR02274 dCTP_deam: deoxycytidine triphosphate deaminase 9 152 1.9E-44 T 23-10-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 A0127_02985 f0a2006d624f72effe82c33ea54ed2e4 431 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 329 415 4.2E-13 T 23-10-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A0127_02985 f0a2006d624f72effe82c33ea54ed2e4 431 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 1 416 8.6E-149 T 23-10-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A0127_02985 f0a2006d624f72effe82c33ea54ed2e4 431 Gene3D G3DSA:3.90.600.10 328 417 1.1E-9 T 23-10-2018 IPR037123 Phosphoribosylglycinamide synthetase, C-domain superfamily GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A0127_02985 f0a2006d624f72effe82c33ea54ed2e4 431 Gene3D G3DSA:3.40.50.20 2 93 1.8E-21 T 23-10-2018 A0127_02985 f0a2006d624f72effe82c33ea54ed2e4 431 SUPERFAMILY SSF52440 1 101 6.62E-24 T 23-10-2018 IPR016185 Pre-ATP-grasp domain superfamily A0127_02985 f0a2006d624f72effe82c33ea54ed2e4 431 SMART SM01209 101 295 2.8E-96 T 23-10-2018 A0127_02985 f0a2006d624f72effe82c33ea54ed2e4 431 Gene3D G3DSA:3.30.1490.20 121 186 7.2E-15 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 A0127_02985 f0a2006d624f72effe82c33ea54ed2e4 431 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 1 100 6.5E-23 T 23-10-2018 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A0127_02985 f0a2006d624f72effe82c33ea54ed2e4 431 SMART SM01210 327 417 2.4E-20 T 23-10-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A0127_02985 f0a2006d624f72effe82c33ea54ed2e4 431 ProSitePatterns PS00184 Phosphoribosylglycinamide synthetase signature. 289 296 - T 23-10-2018 IPR020559 Phosphoribosylglycinamide synthetase, conserved site GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A0127_02985 f0a2006d624f72effe82c33ea54ed2e4 431 SUPERFAMILY SSF51246 326 416 1.65E-16 T 23-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 A0127_02985 f0a2006d624f72effe82c33ea54ed2e4 431 Gene3D G3DSA:3.30.470.20 188 327 2.7E-47 T 23-10-2018 A0127_02985 f0a2006d624f72effe82c33ea54ed2e4 431 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 101 295 2.7E-60 T 23-10-2018 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A0127_02985 f0a2006d624f72effe82c33ea54ed2e4 431 SUPERFAMILY SSF56059 102 320 1.47E-49 T 23-10-2018 A0127_02985 f0a2006d624f72effe82c33ea54ed2e4 431 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 1 417 36.899 T 23-10-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A0127_02600 d988669cf3f30d6796ad2554690a068a 359 SUPERFAMILY SSF102114 39 214 1.44E-13 T 23-10-2018 A0127_02600 d988669cf3f30d6796ad2554690a068a 359 Gene3D G3DSA:3.20.20.70 39 225 3.1E-10 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A0127_02600 d988669cf3f30d6796ad2554690a068a 359 Pfam PF04459 Protein of unknown function (DUF512) 247 328 8.2E-11 T 23-10-2018 IPR007549 Domain of unknown function DUF512 A0127_01240 d5b336baa91d4332aff8c578298b2a82 95 Pfam PF02594 Uncharacterised ACR, YggU family COG1872 11 81 1.4E-25 T 23-10-2018 IPR003746 Protein of unknown function DUF167 A0127_01240 d5b336baa91d4332aff8c578298b2a82 95 SMART SM01152 8 83 9.4E-37 T 23-10-2018 IPR003746 Protein of unknown function DUF167 A0127_01240 d5b336baa91d4332aff8c578298b2a82 95 SUPERFAMILY SSF69786 3 93 1.57E-29 T 23-10-2018 IPR036591 YggU-like superfamily A0127_01240 d5b336baa91d4332aff8c578298b2a82 95 TIGRFAM TIGR00251 TIGR00251: TIGR00251 family protein 5 83 1.2E-28 T 23-10-2018 IPR005228 Conserved hypothetical protein CHP00251 A0127_01240 d5b336baa91d4332aff8c578298b2a82 95 Hamap MF_00634 UPF0235 protein YggU [yggU]. 8 95 21.227 T 23-10-2018 IPR003746 Protein of unknown function DUF167 A0127_01240 d5b336baa91d4332aff8c578298b2a82 95 Gene3D G3DSA:3.30.1200.10 1 95 3.4E-33 T 23-10-2018 IPR036591 YggU-like superfamily A0127_09400 9f0e1eb7e72f388f36adef7b3d093fec 113 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 2 104 9.4E-23 T 23-10-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like A0127_04985 66a88a9d112860542504c321d72803ff 442 Pfam PF13167 GTP-binding GTPase N-terminal 18 100 9.2E-23 T 23-10-2018 IPR025121 GTPase HflX, N-terminal A0127_04985 66a88a9d112860542504c321d72803ff 442 Pfam PF01926 50S ribosome-binding GTPase 188 307 2.8E-19 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A0127_04985 66a88a9d112860542504c321d72803ff 442 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 10 351 1.3E-92 T 23-10-2018 IPR016496 GTPase HflX GO:0005525 A0127_04985 66a88a9d112860542504c321d72803ff 442 PIRSF PIRSF006809 1 422 3.7E-123 T 23-10-2018 IPR016496 GTPase HflX GO:0005525 A0127_04985 66a88a9d112860542504c321d72803ff 442 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 188 344 2.4E-12 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A0127_04985 66a88a9d112860542504c321d72803ff 442 SUPERFAMILY SSF52540 188 404 2.52E-37 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_04985 66a88a9d112860542504c321d72803ff 442 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 254 272 4.7E-7 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A0127_04985 66a88a9d112860542504c321d72803ff 442 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 188 208 4.7E-7 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A0127_04985 66a88a9d112860542504c321d72803ff 442 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 209 227 4.7E-7 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A0127_04985 66a88a9d112860542504c321d72803ff 442 Gene3D G3DSA:3.40.50.300 187 362 2.1E-41 T 23-10-2018 A0127_04985 66a88a9d112860542504c321d72803ff 442 Gene3D G3DSA:3.40.50.11060 8 129 2.9E-33 T 23-10-2018 A0127_04985 66a88a9d112860542504c321d72803ff 442 Hamap MF_00900 GTPase HflX [hflX]. 17 391 42.97 T 23-10-2018 IPR016496 GTPase HflX GO:0005525 A0127_04985 66a88a9d112860542504c321d72803ff 442 Pfam PF16360 GTP-binding GTPase Middle Region 103 180 3.3E-18 T 23-10-2018 IPR032305 GTP-binding protein, middle domain A0127_07575 1f15c0123b2fe720ba32062a3ada2615 235 Gene3D G3DSA:3.30.230.10 123 214 1.4E-29 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A0127_07575 1f15c0123b2fe720ba32062a3ada2615 235 TIGRFAM TIGR01020 uS5_euk_arch: ribosomal protein uS5 10 221 3.0E-106 T 23-10-2018 IPR005711 Ribosomal protein S5, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-3214858|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8876725|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_07575 1f15c0123b2fe720ba32062a3ada2615 235 ProSitePatterns PS00585 Ribosomal protein S5 signature. 77 109 - T 23-10-2018 IPR018192 Ribosomal protein S5, N-terminal, conserved site A0127_07575 1f15c0123b2fe720ba32062a3ada2615 235 Pfam PF00333 Ribosomal protein S5, N-terminal domain 62 123 2.5E-21 T 23-10-2018 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 A0127_07575 1f15c0123b2fe720ba32062a3ada2615 235 SUPERFAMILY SSF54768 62 125 1.57E-18 T 23-10-2018 A0127_07575 1f15c0123b2fe720ba32062a3ada2615 235 SUPERFAMILY SSF54211 138 210 4.8E-19 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A0127_07575 1f15c0123b2fe720ba32062a3ada2615 235 Pfam PF03719 Ribosomal protein S5, C-terminal domain 145 210 5.3E-21 T 23-10-2018 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 A0127_07575 1f15c0123b2fe720ba32062a3ada2615 235 Hamap MF_01307_A 30S ribosomal protein S5 [rpsE]. 8 212 48.053 T 23-10-2018 IPR005711 Ribosomal protein S5, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-3214858|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8876725|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_07575 1f15c0123b2fe720ba32062a3ada2615 235 Gene3D G3DSA:3.30.160.770 12 122 1.6E-37 T 23-10-2018 A0127_07850 9c3bcc22b90556bbf6cbaecf0e4dbfe5 373 Hamap MF_00354 Isopentenyl-diphosphate delta-isomerase [fni]. 10 353 41.063 T 23-10-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 A0127_07850 9c3bcc22b90556bbf6cbaecf0e4dbfe5 373 SMART SM01240 30 349 0.0019 T 23-10-2018 A0127_07850 9c3bcc22b90556bbf6cbaecf0e4dbfe5 373 TIGRFAM TIGR02151 IPP_isom_2: isopentenyl-diphosphate delta-isomerase, type 2 13 352 8.0E-131 T 23-10-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 A0127_07850 9c3bcc22b90556bbf6cbaecf0e4dbfe5 373 Gene3D G3DSA:3.20.20.70 10 373 1.6E-128 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A0127_07850 9c3bcc22b90556bbf6cbaecf0e4dbfe5 373 Pfam PF01070 FMN-dependent dehydrogenase 186 346 6.0E-16 T 23-10-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 Reactome: R-HSA-9033241 A0127_07850 9c3bcc22b90556bbf6cbaecf0e4dbfe5 373 Pfam PF01070 FMN-dependent dehydrogenase 14 105 1.1E-8 T 23-10-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 Reactome: R-HSA-9033241 A0127_07850 9c3bcc22b90556bbf6cbaecf0e4dbfe5 373 PIRSF PIRSF003314 7 363 7.6E-133 T 23-10-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 A0127_07850 9c3bcc22b90556bbf6cbaecf0e4dbfe5 373 SUPERFAMILY SSF51395 32 369 1.2E-80 T 23-10-2018 A0127_02910 096cdbb5aa5d0601d33b4dcd062674cf 122 SUPERFAMILY SSF81301 13 115 2.26E-17 T 23-10-2018 A0127_02910 096cdbb5aa5d0601d33b4dcd062674cf 122 Gene3D G3DSA:3.30.460.10 26 121 1.8E-17 T 23-10-2018 A0127_02910 096cdbb5aa5d0601d33b4dcd062674cf 122 Pfam PF01909 Nucleotidyltransferase domain 32 92 4.3E-9 T 23-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 A0127_06170 73450d56fe07a2f943209008bd45aaa6 254 Gene3D G3DSA:3.40.50.620 2 254 2.8E-93 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A0127_06170 73450d56fe07a2f943209008bd45aaa6 254 Hamap MF_00193 NH(3)-dependent NAD(+) synthetase [nadE]. 5 252 51.843 T 23-10-2018 IPR022926 NH(3)-dependent NAD(+) synthetase GO:0008795|GO:0009435 KEGG: 00760+6.3.1.5 A0127_06170 73450d56fe07a2f943209008bd45aaa6 254 SUPERFAMILY SSF52402 3 250 2.87E-78 T 23-10-2018 A0127_06170 73450d56fe07a2f943209008bd45aaa6 254 Pfam PF02540 NAD synthase 10 249 3.7E-87 T 23-10-2018 IPR022310 NAD/GMP synthase A0127_06170 73450d56fe07a2f943209008bd45aaa6 254 ProSitePatterns PS00304 Small, acid-soluble spore proteins, alpha/beta type, signature 1. 218 227 - T 23-10-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 A0127_06170 73450d56fe07a2f943209008bd45aaa6 254 TIGRFAM TIGR00552 nadE: NAD+ synthetase 7 249 2.1E-83 T 23-10-2018 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 A0127_00960 849053ad026cda9628db44c78267af8a 456 Gene3D G3DSA:1.20.1270.20 32 117 6.1E-28 T 23-10-2018 IPR016100 Prismane, alpha-bundle GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 A0127_00960 849053ad026cda9628db44c78267af8a 456 Hamap MF_00069 Hydroxylamine reductase [hcp]. 11 440 16.511 T 23-10-2018 IPR010048 Hydroxylamine reductase GO:0005737|GO:0016661|GO:0051536|GO:0055114 KEGG: 00910+1.7.99.1 A0127_00960 849053ad026cda9628db44c78267af8a 456 TIGRFAM TIGR01703 hybrid_clust: hydroxylamine reductase 34 439 8.5E-191 T 23-10-2018 IPR010048 Hydroxylamine reductase GO:0005737|GO:0016661|GO:0051536|GO:0055114 KEGG: 00910+1.7.99.1 A0127_00960 849053ad026cda9628db44c78267af8a 456 Gene3D G3DSA:3.40.50.2030 271 439 9.8E-61 T 23-10-2018 IPR016099 Prismane-like, alpha/beta-sandwich GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 A0127_00960 849053ad026cda9628db44c78267af8a 456 Pfam PF03063 Prismane/CO dehydrogenase family 90 435 3.5E-99 T 23-10-2018 IPR004137 Hydroxylamine reductase/Ni-containing CO dehydrogenase GO:0016491|GO:0055114 KEGG: 00910+1.7.99.1 A0127_00960 849053ad026cda9628db44c78267af8a 456 SUPERFAMILY SSF56821 9 439 6.41E-150 T 23-10-2018 IPR011254 Prismane-like superfamily GO:0003824|GO:0016491|GO:0055114 A0127_00960 849053ad026cda9628db44c78267af8a 456 Gene3D G3DSA:3.40.50.2030 123 270 3.3E-56 T 23-10-2018 IPR016099 Prismane-like, alpha/beta-sandwich GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 A0127_00960 849053ad026cda9628db44c78267af8a 456 Pfam PF03063 Prismane/CO dehydrogenase family 11 93 9.0E-17 T 23-10-2018 IPR004137 Hydroxylamine reductase/Ni-containing CO dehydrogenase GO:0016491|GO:0055114 KEGG: 00910+1.7.99.1 A0127_06015 4dd10411da1944a6ce74cbfaa9d77ba4 205 Gene3D G3DSA:3.40.630.20 1 203 8.4E-77 T 23-10-2018 IPR036440 Peptidase C15, pyroglutamyl peptidase I-like superfamily MetaCyc: PWY-7942 A0127_06015 4dd10411da1944a6ce74cbfaa9d77ba4 205 PIRSF PIRSF015592 1 204 4.9E-78 T 23-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 A0127_06015 4dd10411da1944a6ce74cbfaa9d77ba4 205 ProSitePatterns PS01333 Pyrrolidone-carboxylate peptidase glutamic acid active site. 67 83 - T 23-10-2018 IPR033693 Pyroglutamyl peptidase I, Glu active site MetaCyc: PWY-7942 A0127_06015 4dd10411da1944a6ce74cbfaa9d77ba4 205 TIGRFAM TIGR00504 pyro_pdase: pyroglutamyl-peptidase I 2 199 2.9E-74 T 23-10-2018 IPR029762 Pyroglutamyl peptidase I, bacterial-type GO:0005829|GO:0006508|GO:0008234|GO:0016920 MetaCyc: PWY-7942 A0127_06015 4dd10411da1944a6ce74cbfaa9d77ba4 205 Pfam PF01470 Pyroglutamyl peptidase 1 199 2.0E-76 T 23-10-2018 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like MetaCyc: PWY-7942 A0127_06015 4dd10411da1944a6ce74cbfaa9d77ba4 205 Hamap MF_00417 Pyrrolidone-carboxylate peptidase [pcp]. 1 198 37.648 T 23-10-2018 IPR029762 Pyroglutamyl peptidase I, bacterial-type GO:0005829|GO:0006508|GO:0008234|GO:0016920 MetaCyc: PWY-7942 A0127_06015 4dd10411da1944a6ce74cbfaa9d77ba4 205 SUPERFAMILY SSF53182 1 199 2.09E-70 T 23-10-2018 IPR036440 Peptidase C15, pyroglutamyl peptidase I-like superfamily MetaCyc: PWY-7942 A0127_06015 4dd10411da1944a6ce74cbfaa9d77ba4 205 ProSitePatterns PS01334 Pyrrolidone-carboxylate peptidase cysteine active site. 128 142 - T 23-10-2018 IPR033694 Pyroglutamyl peptidase I, Cys active site MetaCyc: PWY-7942 A0127_06015 4dd10411da1944a6ce74cbfaa9d77ba4 205 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 130 146 3.8E-42 T 23-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 A0127_06015 4dd10411da1944a6ce74cbfaa9d77ba4 205 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 78 98 3.8E-42 T 23-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 A0127_06015 4dd10411da1944a6ce74cbfaa9d77ba4 205 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 160 172 3.8E-42 T 23-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 A0127_06015 4dd10411da1944a6ce74cbfaa9d77ba4 205 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 3 26 3.8E-42 T 23-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 A0127_06015 4dd10411da1944a6ce74cbfaa9d77ba4 205 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 60 72 3.8E-42 T 23-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 A0127_01310 078194249f05e1b4c8be177facfc52c9 811 Hamap MF_01886 tRNA(Met) cytidine acetyltransferase TmcA [tmcA]. 39 807 47.874 T 23-10-2018 IPR024914 tRNA(Met) cytidine acetyltransferase TmcA GO:0000049|GO:0002101|GO:0051391|GO:0051392 A0127_01310 078194249f05e1b4c8be177facfc52c9 811 Gene3D G3DSA:3.40.50.12320 281 448 4.3E-33 T 23-10-2018 A0127_01310 078194249f05e1b4c8be177facfc52c9 811 Pfam PF13718 GNAT acetyltransferase 2 498 614 1.5E-32 T 23-10-2018 IPR000182 GNAT domain A0127_01310 078194249f05e1b4c8be177facfc52c9 811 SUPERFAMILY SSF55729 490 644 1.18E-10 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase A0127_01310 078194249f05e1b4c8be177facfc52c9 811 SUPERFAMILY SSF52540 259 397 9.41E-7 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_01310 078194249f05e1b4c8be177facfc52c9 811 Pfam PF08351 Domain of unknown function (DUF1726) 129 221 5.7E-33 T 23-10-2018 IPR013562 tRNA(Met) cytidine acetyltransferase TmcA, N-terminal Reactome: R-HSA-6790901 A0127_01310 078194249f05e1b4c8be177facfc52c9 811 Gene3D G3DSA:3.40.630.30 457 662 4.1E-55 T 23-10-2018 A0127_01310 078194249f05e1b4c8be177facfc52c9 811 Pfam PF05127 Helicase 285 458 7.0E-55 T 23-10-2018 IPR007807 Helicase domain Reactome: R-HSA-6790901 A0127_01310 078194249f05e1b4c8be177facfc52c9 811 Gene3D G3DSA:3.40.50.11040 24 252 9.2E-13 T 23-10-2018 A0127_01505 ac7e6aa74d7aa3dd739725fc06aae909 638 ProSitePatterns PS00932 Prokaryotic molybdopterin oxidoreductases signature 3. 559 586 - T 23-10-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 A0127_01505 ac7e6aa74d7aa3dd739725fc06aae909 638 Gene3D G3DSA:3.40.50.740 68 451 2.1E-122 T 23-10-2018 A0127_01505 ac7e6aa74d7aa3dd739725fc06aae909 638 Gene3D G3DSA:3.40.228.10 134 506 2.1E-122 T 23-10-2018 A0127_01505 ac7e6aa74d7aa3dd739725fc06aae909 638 Gene3D G3DSA:2.40.40.20 518 638 8.8E-30 T 23-10-2018 A0127_01505 ac7e6aa74d7aa3dd739725fc06aae909 638 Pfam PF00384 Molybdopterin oxidoreductase 57 435 8.3E-47 T 23-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A0127_01505 ac7e6aa74d7aa3dd739725fc06aae909 638 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 5 48 2.2E-7 T 23-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A0127_01505 ac7e6aa74d7aa3dd739725fc06aae909 638 SMART SM00926 1 54 1.4E-7 T 23-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A0127_01505 ac7e6aa74d7aa3dd739725fc06aae909 638 Gene3D G3DSA:2.20.25.90 2 59 7.9E-10 T 23-10-2018 A0127_01505 ac7e6aa74d7aa3dd739725fc06aae909 638 SUPERFAMILY SSF53706 4 519 5.37E-140 T 23-10-2018 A0127_01505 ac7e6aa74d7aa3dd739725fc06aae909 638 SUPERFAMILY SSF50692 517 637 3.32E-33 T 23-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily A0127_01505 ac7e6aa74d7aa3dd739725fc06aae909 638 Pfam PF01568 Molydopterin dinucleotide binding domain 531 630 4.4E-22 T 23-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 A0127_01505 ac7e6aa74d7aa3dd739725fc06aae909 638 Gene3D G3DSA:3.30.2070.10 408 488 2.1E-122 T 23-10-2018 A0127_01260 4914a781df6f26a74e00e54c14f631e0 350 Pfam PF00535 Glycosyl transferase family 2 41 201 5.5E-36 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A0127_01260 4914a781df6f26a74e00e54c14f631e0 350 Gene3D G3DSA:3.90.550.10 28 242 4.8E-47 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A0127_01260 4914a781df6f26a74e00e54c14f631e0 350 SUPERFAMILY SSF53448 32 275 4.28E-55 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A0127_04140 9c63b686e1a88f4620e7b1cd73569fcc 306 SUPERFAMILY SSF56235 18 298 4.89E-86 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A0127_04140 9c63b686e1a88f4620e7b1cd73569fcc 306 Gene3D G3DSA:3.60.20.30 176 303 3.6E-33 T 23-10-2018 A0127_04140 9c63b686e1a88f4620e7b1cd73569fcc 306 Pfam PF01112 Asparaginase 3 298 6.3E-93 T 23-10-2018 IPR000246 Peptidase T2, asparaginase 2 GO:0016787 A0127_01745 0a77cc591105783452c258a2be6bf5d4 123 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 6 122 19.83 T 23-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 A0127_01745 0a77cc591105783452c258a2be6bf5d4 123 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 7 117 2.7E-25 T 23-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 A0127_01745 0a77cc591105783452c258a2be6bf5d4 123 TIGRFAM TIGR00494 crcB: protein CrcB 8 121 1.4E-28 T 23-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 A0127_03135 fa3292542a57156e22d372f2fa6c0d18 281 SMART SM00518 4 276 1.3E-96 T 23-10-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 A0127_03135 fa3292542a57156e22d372f2fa6c0d18 281 SUPERFAMILY SSF51658 7 278 2.49E-63 T 23-10-2018 IPR036237 Xylose isomerase-like superfamily A0127_03135 fa3292542a57156e22d372f2fa6c0d18 281 Pfam PF01261 Xylose isomerase-like TIM barrel 28 239 1.1E-20 T 23-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain A0127_03135 fa3292542a57156e22d372f2fa6c0d18 281 Gene3D G3DSA:3.20.20.150 13 280 6.0E-43 T 23-10-2018 A0127_03145 f2fc778e49083ea4a009991f9d25f64c 77 Gene3D G3DSA:3.30.70.920 1 71 1.6E-10 T 23-10-2018 A0127_03145 f2fc778e49083ea4a009991f9d25f64c 77 SUPERFAMILY SSF54909 2 72 4.42E-9 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel A0127_03145 f2fc778e49083ea4a009991f9d25f64c 77 Pfam PF01037 Lrp/AsnC ligand binding domain 14 72 1.2E-7 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A0127_09470 f9c2328b49314f43876972c2ab00c3f9 671 Pfam PF00361 Proton-conducting membrane transporter 124 425 1.2E-49 T 23-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A0127_09470 f9c2328b49314f43876972c2ab00c3f9 671 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 65 90 5.0E-10 T 23-10-2018 A0127_09470 f9c2328b49314f43876972c2ab00c3f9 671 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 302 314 5.0E-10 T 23-10-2018 A0127_09470 f9c2328b49314f43876972c2ab00c3f9 671 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 211 232 5.0E-10 T 23-10-2018 A0127_09470 f9c2328b49314f43876972c2ab00c3f9 671 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 58 91 9.7E-8 T 23-10-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A0127_10175 db91bb1a5af116ef7d5e272c87dbec77 393 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 148 279 1.1E-37 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A0127_10175 db91bb1a5af116ef7d5e272c87dbec77 393 SMART SM00382 144 281 8.0E-16 T 23-10-2018 IPR003593 AAA+ ATPase domain A0127_10175 db91bb1a5af116ef7d5e272c87dbec77 393 Gene3D G3DSA:3.40.50.300 109 388 1.0E-84 T 23-10-2018 A0127_10175 db91bb1a5af116ef7d5e272c87dbec77 393 ProSitePatterns PS00674 AAA-protein family signature. 251 270 - T 23-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 A0127_10175 db91bb1a5af116ef7d5e272c87dbec77 393 Gene3D G3DSA:1.10.8.60 280 372 1.0E-84 T 23-10-2018 A0127_10175 db91bb1a5af116ef7d5e272c87dbec77 393 Pfam PF09336 Vps4 C terminal oligomerisation domain 347 392 3.8E-8 T 23-10-2018 IPR015415 Vps4 oligomerisation, C-terminal A0127_10175 db91bb1a5af116ef7d5e272c87dbec77 393 SUPERFAMILY SSF52540 112 391 2.76E-55 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_01815 1ffd03473ea7f0b3779eecdae0974140 114 Gene3D G3DSA:2.60.120.10 8 102 4.9E-22 T 23-10-2018 IPR014710 RmlC-like jelly roll fold A0127_01815 1ffd03473ea7f0b3779eecdae0974140 114 SUPERFAMILY SSF51182 10 101 2.9E-24 T 23-10-2018 IPR011051 RmlC-like cupin domain superfamily A0127_01815 1ffd03473ea7f0b3779eecdae0974140 114 Pfam PF07883 Cupin domain 32 100 4.2E-19 T 23-10-2018 IPR013096 Cupin 2, conserved barrel A0127_01775 ae87e48824f89fa24bd66f94067d339c 478 Pfam PF00224 Pyruvate kinase, barrel domain 6 338 1.5E-118 T 23-10-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A0127_01775 ae87e48824f89fa24bd66f94067d339c 478 Gene3D G3DSA:3.20.20.60 7 336 9.1E-166 T 23-10-2018 A0127_01775 ae87e48824f89fa24bd66f94067d339c 478 Gene3D G3DSA:3.40.1380.20 337 474 9.1E-166 T 23-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A0127_01775 ae87e48824f89fa24bd66f94067d339c 478 PRINTS PR01050 Pyruvate kinase family signature 245 269 1.6E-64 T 23-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A0127_01775 ae87e48824f89fa24bd66f94067d339c 478 PRINTS PR01050 Pyruvate kinase family signature 270 294 1.6E-64 T 23-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A0127_01775 ae87e48824f89fa24bd66f94067d339c 478 PRINTS PR01050 Pyruvate kinase family signature 63 79 1.6E-64 T 23-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A0127_01775 ae87e48824f89fa24bd66f94067d339c 478 PRINTS PR01050 Pyruvate kinase family signature 188 202 1.6E-64 T 23-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A0127_01775 ae87e48824f89fa24bd66f94067d339c 478 PRINTS PR01050 Pyruvate kinase family signature 295 313 1.6E-64 T 23-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A0127_01775 ae87e48824f89fa24bd66f94067d339c 478 PRINTS PR01050 Pyruvate kinase family signature 314 330 1.6E-64 T 23-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A0127_01775 ae87e48824f89fa24bd66f94067d339c 478 PRINTS PR01050 Pyruvate kinase family signature 218 244 1.6E-64 T 23-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A0127_01775 ae87e48824f89fa24bd66f94067d339c 478 SUPERFAMILY SSF52935 324 478 7.46E-32 T 23-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A0127_01775 ae87e48824f89fa24bd66f94067d339c 478 ProSitePatterns PS00110 Pyruvate kinase active site signature. 216 228 - T 23-10-2018 IPR018209 Pyruvate kinase, active site GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A0127_01775 ae87e48824f89fa24bd66f94067d339c 478 Gene3D G3DSA:2.40.33.10 74 170 9.1E-166 T 23-10-2018 IPR015806 Pyruvate kinase, insert domain superfamily GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A0127_01775 ae87e48824f89fa24bd66f94067d339c 478 Pfam PF02887 Pyruvate kinase, alpha/beta domain 368 475 4.5E-23 T 23-10-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A0127_01775 ae87e48824f89fa24bd66f94067d339c 478 SUPERFAMILY SSF50800 75 167 1.74E-24 T 23-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily A0127_01775 ae87e48824f89fa24bd66f94067d339c 478 SUPERFAMILY SSF51621 6 340 5.93E-93 T 23-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 A0127_01775 ae87e48824f89fa24bd66f94067d339c 478 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 6 478 1.4E-167 T 23-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 A0127_00290 63f75a5b17fec233f9e80cbc6ba8e4d5 364 SUPERFAMILY SSF47240 4 139 1.8E-14 T 23-10-2018 IPR009078 Ferritin-like superfamily A0127_00290 63f75a5b17fec233f9e80cbc6ba8e4d5 364 Pfam PF02915 Rubrerythrin 12 139 3.4E-8 T 23-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 A0127_00290 63f75a5b17fec233f9e80cbc6ba8e4d5 364 Pfam PF01988 VIT family 148 353 8.6E-46 T 23-10-2018 IPR008217 Ccc1 family A0127_00290 63f75a5b17fec233f9e80cbc6ba8e4d5 364 Gene3D G3DSA:1.20.1260.10 2 143 2.5E-8 T 23-10-2018 IPR012347 Ferritin-like A0127_09455 3886c9ffbe565eadf2b29d8d3c20d1ad 686 Pfam PF00384 Molybdopterin oxidoreductase 62 487 8.1E-95 T 23-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A0127_09455 3886c9ffbe565eadf2b29d8d3c20d1ad 686 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 4 59 6.8E-12 T 23-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A0127_09455 3886c9ffbe565eadf2b29d8d3c20d1ad 686 SMART SM00926 3 59 2.9E-14 T 23-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A0127_09455 3886c9ffbe565eadf2b29d8d3c20d1ad 686 Gene3D G3DSA:2.40.40.20 564 686 1.4E-42 T 23-10-2018 A0127_09455 3886c9ffbe565eadf2b29d8d3c20d1ad 686 Pfam PF01568 Molydopterin dinucleotide binding domain 575 677 3.3E-32 T 23-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 A0127_09455 3886c9ffbe565eadf2b29d8d3c20d1ad 686 TIGRFAM TIGR01591 Fdh-alpha: formate dehydrogenase, alpha subunit 8 681 1.1E-202 T 23-10-2018 IPR006478 Formate dehydrogenase, alpha subunit GO:0008863|GO:0015942|GO:0055114 KEGG: 00630+1.17.1.9|KEGG: 00680+1.17.1.9|MetaCyc: PWY-1881|MetaCyc: PWY-5497|MetaCyc: PWY-6696|MetaCyc: PWY-7985 A0127_09455 3886c9ffbe565eadf2b29d8d3c20d1ad 686 Gene3D G3DSA:3.40.228.10 143 342 1.8E-157 T 23-10-2018 A0127_09455 3886c9ffbe565eadf2b29d8d3c20d1ad 686 SUPERFAMILY SSF53706 3 577 9.82E-189 T 23-10-2018 A0127_09455 3886c9ffbe565eadf2b29d8d3c20d1ad 686 ProSitePatterns PS00490 Prokaryotic molybdopterin oxidoreductases signature 2. 433 450 - T 23-10-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 A0127_09455 3886c9ffbe565eadf2b29d8d3c20d1ad 686 Gene3D G3DSA:2.20.25.90 4 59 8.9E-14 T 23-10-2018 A0127_09455 3886c9ffbe565eadf2b29d8d3c20d1ad 686 Gene3D G3DSA:3.40.50.740 74 533 1.8E-157 T 23-10-2018 A0127_09455 3886c9ffbe565eadf2b29d8d3c20d1ad 686 SUPERFAMILY SSF50692 547 684 3.06E-47 T 23-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily A0127_02035 3d17e3b2b7fda0c6ff19176e142313cb 318 SMART SM00530 130 185 1.0E-11 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A0127_02035 3d17e3b2b7fda0c6ff19176e142313cb 318 Hamap MF_00584 Putative HTH-type transcriptional regulatory protein . 2 300 28.345 T 23-10-2018 IPR020886 Transcription regulator HTH, Cro/C1-type DNA-binding GO:0003700|GO:0006355 A0127_02035 3d17e3b2b7fda0c6ff19176e142313cb 318 Gene3D G3DSA:1.10.260.40 126 206 2.0E-12 T 23-10-2018 A0127_02035 3d17e3b2b7fda0c6ff19176e142313cb 318 SUPERFAMILY SSF47413 126 183 1.56E-12 T 23-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A0127_02035 3d17e3b2b7fda0c6ff19176e142313cb 318 Pfam PF01381 Helix-turn-helix 131 183 8.6E-13 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A0127_09620 57811ca086829ed1191a485c6d01eb08 601 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 220 599 4.7E-65 T 23-10-2018 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 A0127_09620 57811ca086829ed1191a485c6d01eb08 601 Gene3D G3DSA:1.10.599.10 410 598 6.0E-66 T 23-10-2018 IPR013985 Aldehyde ferredoxin oxidoreductase, domain 3 GO:0016625|GO:0051536|GO:0055114 KEGG: 00030+1.2.7.5 A0127_09620 57811ca086829ed1191a485c6d01eb08 601 Gene3D G3DSA:3.60.9.10 1 208 3.3E-73 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily A0127_09620 57811ca086829ed1191a485c6d01eb08 601 SMART SM00790 4 204 7.4E-107 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 A0127_09620 57811ca086829ed1191a485c6d01eb08 601 SUPERFAMILY SSF56228 1 207 1.96E-66 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily A0127_09620 57811ca086829ed1191a485c6d01eb08 601 SUPERFAMILY SSF48310 208 601 8.89E-83 T 23-10-2018 IPR036021 Aldehyde ferredoxin oxidoreductase-like, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 A0127_09620 57811ca086829ed1191a485c6d01eb08 601 Gene3D G3DSA:1.10.569.10 256 409 6.0E-66 T 23-10-2018 IPR013984 Aldehyde ferredoxin oxidoreductase, domain 2 A0127_09620 57811ca086829ed1191a485c6d01eb08 601 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 6 203 9.1E-70 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 A0127_05825 d343070df514089aa6f6687abeb69896 469 Gene3D G3DSA:3.40.50.261 302 466 2.8E-44 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A0127_05825 d343070df514089aa6f6687abeb69896 469 Gene3D G3DSA:3.40.50.720 4 134 5.6E-44 T 23-10-2018 A0127_05825 d343070df514089aa6f6687abeb69896 469 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 161 297 5.1E-57 T 23-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain A0127_05825 d343070df514089aa6f6687abeb69896 469 SMART SM00881 9 107 3.7E-39 T 23-10-2018 IPR003781 CoA-binding GO:0048037 A0127_05825 d343070df514089aa6f6687abeb69896 469 SUPERFAMILY SSF52210 136 298 4.58E-42 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A0127_05825 d343070df514089aa6f6687abeb69896 469 Gene3D G3DSA:3.40.50.261 136 300 6.9E-60 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A0127_05825 d343070df514089aa6f6687abeb69896 469 Pfam PF13380 CoA binding domain 13 139 9.9E-24 T 23-10-2018 IPR003781 CoA-binding GO:0048037 A0127_05825 d343070df514089aa6f6687abeb69896 469 SUPERFAMILY SSF52210 304 463 3.4E-34 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A0127_05825 d343070df514089aa6f6687abeb69896 469 SUPERFAMILY SSF51735 6 135 8.25E-38 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A0127_03160 39dde644a4abe276247f1a2becfc0c5b 542 SUPERFAMILY SSF161098 4 259 7.98E-51 T 23-10-2018 IPR035906 MetI-like superfamily A0127_03160 39dde644a4abe276247f1a2becfc0c5b 542 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 75 257 7.0E-16 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A0127_03160 39dde644a4abe276247f1a2becfc0c5b 542 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 364 533 4.7E-12 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A0127_03160 39dde644a4abe276247f1a2becfc0c5b 542 Gene3D G3DSA:1.10.3720.10 288 540 7.6E-57 T 23-10-2018 IPR035906 MetI-like superfamily A0127_03160 39dde644a4abe276247f1a2becfc0c5b 542 Gene3D G3DSA:1.10.3720.10 6 265 5.2E-59 T 23-10-2018 IPR035906 MetI-like superfamily A0127_03160 39dde644a4abe276247f1a2becfc0c5b 542 SUPERFAMILY SSF161098 291 536 1.05E-54 T 23-10-2018 IPR035906 MetI-like superfamily A0127_03415 aada101e342b36d9249d44691f2ada04 157 SUPERFAMILY SSF56271 2 155 1.57E-46 T 23-10-2018 IPR016104 Pyruvoyl-dependent histidine/arginine decarboxylase GO:0006520|GO:0016831 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 A0127_03415 aada101e342b36d9249d44691f2ada04 157 Gene3D G3DSA:3.50.20.10 44 155 3.9E-35 T 23-10-2018 IPR016105 Pyruvoyl-dependent histidine/arginine decarboxylase, 3-layer sandwich domain GO:0006520|GO:0016831 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 A0127_03415 aada101e342b36d9249d44691f2ada04 157 Hamap MF_01404 Pyruvoyl-dependent arginine decarboxylase [pdaD]. 1 157 47.437 T 23-10-2018 IPR002724 Pyruvoyl-dependent arginine decarboxylase GO:0006527|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 A0127_03415 aada101e342b36d9249d44691f2ada04 157 Pfam PF01862 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) 5 154 1.1E-40 T 23-10-2018 IPR002724 Pyruvoyl-dependent arginine decarboxylase GO:0006527|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 A0127_03415 aada101e342b36d9249d44691f2ada04 157 Gene3D G3DSA:3.30.60.30 1 43 3.4E-18 T 23-10-2018 A0127_03415 aada101e342b36d9249d44691f2ada04 157 TIGRFAM TIGR00286 TIGR00286: arginine decarboxylase, pyruvoyl-dependent 6 153 2.9E-39 T 23-10-2018 IPR002724 Pyruvoyl-dependent arginine decarboxylase GO:0006527|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 A0127_03415 aada101e342b36d9249d44691f2ada04 157 ProDom PD010449 DECARBOXYLASE PYRUVOYL-DEPENDENT ARGININE SUBUNIT ALPHA CONTAINS: BETA PVLARGDC LYA DECARBOX 6 141 9.0E-74 T 23-10-2018 IPR002724 Pyruvoyl-dependent arginine decarboxylase GO:0006527|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 A0127_03415 aada101e342b36d9249d44691f2ada04 157 PIRSF PIRSF005216 2 157 2.7E-47 T 23-10-2018 IPR002724 Pyruvoyl-dependent arginine decarboxylase GO:0006527|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 A0127_08870 b15bf20f62dc70acaf164c7b88a1bd90 443 Gene3D G3DSA:3.40.640.10 59 324 2.5E-148 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A0127_08870 b15bf20f62dc70acaf164c7b88a1bd90 443 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 241 278 - T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A0127_08870 b15bf20f62dc70acaf164c7b88a1bd90 443 Pfam PF00202 Aminotransferase class-III 21 424 4.4E-112 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A0127_08870 b15bf20f62dc70acaf164c7b88a1bd90 443 PIRSF PIRSF000521 7 132 2.9E-6 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A0127_08870 b15bf20f62dc70acaf164c7b88a1bd90 443 PIRSF PIRSF000521 124 427 8.2E-34 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A0127_08870 b15bf20f62dc70acaf164c7b88a1bd90 443 Gene3D G3DSA:3.90.1150.10 5 420 2.5E-148 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A0127_08870 b15bf20f62dc70acaf164c7b88a1bd90 443 SUPERFAMILY SSF53383 16 427 2.81E-128 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A0127_00905 44deb293ccbd389b78f5b0efe2184e80 371 Pfam PF01458 Uncharacterized protein family (UPF0051) 132 343 1.1E-31 T 23-10-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 A0127_00905 44deb293ccbd389b78f5b0efe2184e80 371 SUPERFAMILY SSF101960 10 352 3.53E-44 T 23-10-2018 IPR037284 SUF system FeS cluster assembly, SufBD superfamily A0127_05100 522628a5510242eee6d259e811ee1dcf 91 ProSitePatterns PS00151 Acylphosphatase signature 2. 34 50 - T 23-10-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 A0127_05100 522628a5510242eee6d259e811ee1dcf 91 Gene3D G3DSA:3.30.70.100 1 91 1.2E-37 T 23-10-2018 A0127_05100 522628a5510242eee6d259e811ee1dcf 91 SUPERFAMILY SSF54975 2 90 4.14E-31 T 23-10-2018 IPR036046 Acylphosphatase-like domain superfamily KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 A0127_05100 522628a5510242eee6d259e811ee1dcf 91 Pfam PF00708 Acylphosphatase 7 88 4.1E-28 T 23-10-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 A0127_05100 522628a5510242eee6d259e811ee1dcf 91 ProSitePatterns PS00150 Acylphosphatase signature 1. 10 20 - T 23-10-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 A0127_05100 522628a5510242eee6d259e811ee1dcf 91 PRINTS PR00112 Acylphosphatase signature 26 51 1.2E-9 T 23-10-2018 IPR020456 Acylphosphatase GO:0003998 KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 A0127_05100 522628a5510242eee6d259e811ee1dcf 91 PRINTS PR00112 Acylphosphatase signature 5 20 1.2E-9 T 23-10-2018 IPR020456 Acylphosphatase GO:0003998 KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 A0127_02055 168218d210bbbee854534e6e11917cfd 249 TIGRFAM TIGR00590 pcna: proliferating cell nuclear antigen (pcna) 3 249 1.6E-39 T 23-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 A0127_02055 168218d210bbbee854534e6e11917cfd 249 Pfam PF00705 Proliferating cell nuclear antigen, N-terminal domain 3 110 2.9E-17 T 23-10-2018 IPR022648 Proliferating cell nuclear antigen, PCNA, N-terminal GO:0003677|GO:0006275 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 A0127_02055 168218d210bbbee854534e6e11917cfd 249 SUPERFAMILY SSF55979 3 117 1.82E-32 T 23-10-2018 A0127_02055 168218d210bbbee854534e6e11917cfd 249 SUPERFAMILY SSF55979 124 247 3.37E-31 T 23-10-2018 A0127_02055 168218d210bbbee854534e6e11917cfd 249 Hamap MF_00317 DNA polymerase sliding clamp [pcn]. 3 247 32.793 T 23-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 A0127_02055 168218d210bbbee854534e6e11917cfd 249 Gene3D G3DSA:3.70.10.10 2 242 2.0E-78 T 23-10-2018 A0127_02055 168218d210bbbee854534e6e11917cfd 249 Pfam PF02747 Proliferating cell nuclear antigen, C-terminal domain 126 245 8.2E-10 T 23-10-2018 IPR022649 Proliferating cell nuclear antigen, PCNA, C-terminal GO:0003677|GO:0006275 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 A0127_02055 168218d210bbbee854534e6e11917cfd 249 ProSitePatterns PS01251 Proliferating cell nuclear antigen signature 1. 35 58 - T 23-10-2018 IPR022659 Proliferating cell nuclear antigen, PCNA, conserved site Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 A0127_02055 168218d210bbbee854534e6e11917cfd 249 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 35 53 1.3E-17 T 23-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 A0127_02055 168218d210bbbee854534e6e11917cfd 249 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 107 129 1.3E-17 T 23-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 A0127_02055 168218d210bbbee854534e6e11917cfd 249 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 11 30 1.3E-17 T 23-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 A0127_02055 168218d210bbbee854534e6e11917cfd 249 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 195 209 1.3E-17 T 23-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 A0127_02055 168218d210bbbee854534e6e11917cfd 249 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 233 249 1.3E-17 T 23-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 A0127_02055 168218d210bbbee854534e6e11917cfd 249 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 57 81 1.3E-17 T 23-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 A0127_01595 e5d165156c396d9b360b27af63730e60 835 ProSitePatterns PS00674 AAA-protein family signature. 681 699 - T 23-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 A0127_01595 e5d165156c396d9b360b27af63730e60 835 Gene3D G3DSA:1.10.8.60 377 416 3.5E-6 T 23-10-2018 A0127_01595 e5d165156c396d9b360b27af63730e60 835 Gene3D G3DSA:1.10.8.60 712 820 5.7E-31 T 23-10-2018 A0127_01595 e5d165156c396d9b360b27af63730e60 835 SUPERFAMILY SSF52540 539 815 7.83E-80 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_01595 e5d165156c396d9b360b27af63730e60 835 Gene3D G3DSA:1.10.8.60 447 533 9.1E-16 T 23-10-2018 A0127_01595 e5d165156c396d9b360b27af63730e60 835 SUPERFAMILY SSF52540 204 529 1.9E-69 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_01595 e5d165156c396d9b360b27af63730e60 835 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 581 710 5.9E-49 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A0127_01595 e5d165156c396d9b360b27af63730e60 835 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 246 375 4.4E-51 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A0127_01595 e5d165156c396d9b360b27af63730e60 835 SMART SM01073 14 98 9.8E-37 T 23-10-2018 IPR003338 CDC48, N-terminal subdomain A0127_01595 e5d165156c396d9b360b27af63730e60 835 Gene3D G3DSA:2.40.40.20 8 98 1.1E-32 T 23-10-2018 A0127_01595 e5d165156c396d9b360b27af63730e60 835 SMART SM00382 242 378 8.0E-26 T 23-10-2018 IPR003593 AAA+ ATPase domain A0127_01595 e5d165156c396d9b360b27af63730e60 835 SMART SM00382 577 713 3.5E-25 T 23-10-2018 IPR003593 AAA+ ATPase domain A0127_01595 e5d165156c396d9b360b27af63730e60 835 SUPERFAMILY SSF50692 12 96 5.09E-27 T 23-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily A0127_01595 e5d165156c396d9b360b27af63730e60 835 Pfam PF02359 Cell division protein 48 (CDC48), N-terminal domain 14 97 3.4E-30 T 23-10-2018 IPR003338 CDC48, N-terminal subdomain A0127_01595 e5d165156c396d9b360b27af63730e60 835 Pfam PF02933 Cell division protein 48 (CDC48), domain 2 121 198 3.4E-13 T 23-10-2018 IPR004201 CDC48, domain 2 A0127_01595 e5d165156c396d9b360b27af63730e60 835 TIGRFAM TIGR01243 CDC48: AAA family ATPase, CDC48 subfamily 13 821 0.0 T 23-10-2018 IPR005938 AAA ATPase, CDC48 family GO:0016787 Reactome: R-HSA-110320|Reactome: R-HSA-3371511|Reactome: R-HSA-382556|Reactome: R-HSA-532668|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5678895|Reactome: R-HSA-5689877|Reactome: R-HSA-5689896|Reactome: R-HSA-6798695|Reactome: R-HSA-8866654|Reactome: R-HSA-8876725 A0127_01595 e5d165156c396d9b360b27af63730e60 835 SUPERFAMILY SSF54585 98 211 5.89E-18 T 23-10-2018 IPR029067 CDC48 domain 2-like superfamily A0127_01595 e5d165156c396d9b360b27af63730e60 835 ProSitePatterns PS00674 AAA-protein family signature. 346 364 - T 23-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 A0127_01595 e5d165156c396d9b360b27af63730e60 835 SMART SM01072 116 198 2.8E-15 T 23-10-2018 IPR004201 CDC48, domain 2 A0127_01595 e5d165156c396d9b360b27af63730e60 835 Gene3D G3DSA:3.40.50.300 535 710 1.2E-75 T 23-10-2018 A0127_01595 e5d165156c396d9b360b27af63730e60 835 Gene3D G3DSA:3.40.50.300 195 375 1.4E-74 T 23-10-2018 A0127_00615 3497d26074eccee9b498454d727382fa 606 Pfam PF05124 S-layer like family, C-terminal region 373 602 3.8E-69 T 23-10-2018 IPR022651 S-layer protein, C-terminal A0127_00615 3497d26074eccee9b498454d727382fa 606 TIGRFAM TIGR01564 S_layer_MJ: S-layer protein 4 602 5.6E-100 T 23-10-2018 IPR006454 S-layer protein GO:0005618 A0127_00615 3497d26074eccee9b498454d727382fa 606 Pfam PF05123 S-layer like family, N-terminal region 4 319 6.6E-77 T 23-10-2018 IPR022650 S-layer protein, N-terminal A0127_03070 7b3b2d893c200fce46c68261527f5696 226 SUPERFAMILY SSF53335 3 225 6.91E-59 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A0127_03070 7b3b2d893c200fce46c68261527f5696 226 Hamap MF_00351 Fibrillarin-like rRNA/tRNA 2'-O-methyltransferase [flpA]. 16 226 43.679 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 A0127_03070 7b3b2d893c200fce46c68261527f5696 226 PRINTS PR00052 Fibrillarin signature 153 182 5.1E-78 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 A0127_03070 7b3b2d893c200fce46c68261527f5696 226 PRINTS PR00052 Fibrillarin signature 204 225 5.1E-78 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 A0127_03070 7b3b2d893c200fce46c68261527f5696 226 PRINTS PR00052 Fibrillarin signature 23 42 5.1E-78 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 A0127_03070 7b3b2d893c200fce46c68261527f5696 226 PRINTS PR00052 Fibrillarin signature 123 152 5.1E-78 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 A0127_03070 7b3b2d893c200fce46c68261527f5696 226 PRINTS PR00052 Fibrillarin signature 73 94 5.1E-78 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 A0127_03070 7b3b2d893c200fce46c68261527f5696 226 PRINTS PR00052 Fibrillarin signature 46 65 5.1E-78 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 A0127_03070 7b3b2d893c200fce46c68261527f5696 226 PRINTS PR00052 Fibrillarin signature 98 115 5.1E-78 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 A0127_03070 7b3b2d893c200fce46c68261527f5696 226 Gene3D G3DSA:3.40.50.150 51 226 6.0E-74 T 23-10-2018 A0127_03070 7b3b2d893c200fce46c68261527f5696 226 SMART SM01206 3 226 6.3E-143 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 A0127_03070 7b3b2d893c200fce46c68261527f5696 226 Gene3D G3DSA:3.30.200.20 1 50 4.3E-25 T 23-10-2018 A0127_03070 7b3b2d893c200fce46c68261527f5696 226 PIRSF PIRSF006540 1 226 1.3E-99 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 A0127_03070 7b3b2d893c200fce46c68261527f5696 226 Pfam PF01269 Fibrillarin 4 224 1.2E-99 T 23-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 A0127_03070 7b3b2d893c200fce46c68261527f5696 226 ProSitePatterns PS00566 Fibrillarin signature. 98 112 - T 23-10-2018 IPR020813 Fibrillarin, conserved site GO:0003723|GO:0006364|GO:0008168 A0127_01830 74208078eb75648148a456ae68286252 331 SUPERFAMILY SSF53335 72 330 9.54E-73 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A0127_01830 74208078eb75648148a456ae68286252 331 Gene3D G3DSA:3.40.50.150 143 331 1.2E-55 T 23-10-2018 A0127_01830 74208078eb75648148a456ae68286252 331 Gene3D G3DSA:3.30.300.110 56 142 1.9E-29 T 23-10-2018 A0127_01830 74208078eb75648148a456ae68286252 331 Pfam PF02475 Met-10+ like-protein 82 277 3.8E-69 T 23-10-2018 IPR030382 SAM-dependent methyltransferase TRM5/TYW2-type Reactome: R-HSA-6782861 A0127_01145 dcc01b5aa71aeba2b4334340df9c1972 256 PRINTS PR00377 Inositol monophosphatase superfamily signature 80 96 4.4E-31 T 23-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A0127_01145 dcc01b5aa71aeba2b4334340df9c1972 256 PRINTS PR00377 Inositol monophosphatase superfamily signature 129 152 4.4E-31 T 23-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A0127_01145 dcc01b5aa71aeba2b4334340df9c1972 256 PRINTS PR00377 Inositol monophosphatase superfamily signature 40 60 4.4E-31 T 23-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A0127_01145 dcc01b5aa71aeba2b4334340df9c1972 256 PRINTS PR00377 Inositol monophosphatase superfamily signature 197 221 4.4E-31 T 23-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A0127_01145 dcc01b5aa71aeba2b4334340df9c1972 256 PRINTS PR00377 Inositol monophosphatase superfamily signature 164 185 4.4E-31 T 23-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A0127_01145 dcc01b5aa71aeba2b4334340df9c1972 256 Gene3D G3DSA:3.40.190.80 144 253 7.6E-31 T 23-10-2018 A0127_01145 dcc01b5aa71aeba2b4334340df9c1972 256 Pfam PF00459 Inositol monophosphatase family 7 253 1.6E-38 T 23-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 A0127_01145 dcc01b5aa71aeba2b4334340df9c1972 256 Gene3D G3DSA:3.30.540.10 2 139 8.8E-36 T 23-10-2018 A0127_01145 dcc01b5aa71aeba2b4334340df9c1972 256 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 80 92 - T 23-10-2018 IPR020583 Inositol monophosphatase, metal-binding site A0127_01145 dcc01b5aa71aeba2b4334340df9c1972 256 SUPERFAMILY SSF56655 6 248 1.96E-56 T 23-10-2018 A0127_06125 75e60fd5f13f9a95559abde483dfa296 302 SMART SM00729 57 254 2.7E-6 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A0127_06125 75e60fd5f13f9a95559abde483dfa296 302 SUPERFAMILY SSF102114 61 263 3.66E-31 T 23-10-2018 A0127_06125 75e60fd5f13f9a95559abde483dfa296 302 Pfam PF04055 Radical SAM superfamily 62 211 3.0E-14 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A0127_06125 75e60fd5f13f9a95559abde483dfa296 302 Gene3D G3DSA:3.20.20.70 52 288 1.9E-30 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A0127_09045 fcd22f85df80edabc9a48c239ea8dada 184 Gene3D G3DSA:3.40.390.10 31 177 2.9E-49 T 23-10-2018 IPR024079 Metallopeptidase, catalytic domain superfamily GO:0008237 A0127_09045 fcd22f85df80edabc9a48c239ea8dada 184 SUPERFAMILY SSF55486 51 172 4.81E-16 T 23-10-2018 A0127_09045 fcd22f85df80edabc9a48c239ea8dada 184 Pfam PF07998 Peptidase family M54 74 176 4.3E-30 T 23-10-2018 IPR012962 Peptidase M54, archaemetzincin GO:0008270 A0127_09045 fcd22f85df80edabc9a48c239ea8dada 184 Hamap MF_01842 Archaemetzincin [amzA]. 1 177 35.78 T 23-10-2018 IPR012091 Peptidase M54, archaemetzincin, archaeal/bacterial GO:0006508|GO:0008237|GO:0008270 A0127_09045 fcd22f85df80edabc9a48c239ea8dada 184 PIRSF PIRSF005785 1 184 1.5E-67 T 23-10-2018 IPR012091 Peptidase M54, archaemetzincin, archaeal/bacterial GO:0006508|GO:0008237|GO:0008270 A0127_07085 ed6afd878836aaeea6b2c5a0d2a2627f 157 SUPERFAMILY SSF51230 81 156 2.62E-27 T 23-10-2018 IPR011053 Single hybrid motif A0127_07085 ed6afd878836aaeea6b2c5a0d2a2627f 157 Pfam PF00364 Biotin-requiring enzyme 91 156 3.0E-25 T 23-10-2018 IPR000089 Biotin/lipoyl attachment A0127_07085 ed6afd878836aaeea6b2c5a0d2a2627f 157 Gene3D G3DSA:2.40.50.100 84 157 1.1E-30 T 23-10-2018 A0127_07085 ed6afd878836aaeea6b2c5a0d2a2627f 157 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 113 130 - T 23-10-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A0127_04120 1c14d1c0900edb842c2b216ff48ac1f9 311 Gene3D G3DSA:1.10.10.10 5 94 3.8E-16 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A0127_04120 1c14d1c0900edb842c2b216ff48ac1f9 311 Pfam PF09202 Rio2, N-terminal 13 93 4.0E-23 T 23-10-2018 IPR015285 RIO2 kinase winged helix domain, N-terminal GO:0004674|GO:0005524|GO:0006468 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6791226 A0127_04120 1c14d1c0900edb842c2b216ff48ac1f9 311 Gene3D G3DSA:3.30.200.20 98 196 6.6E-23 T 23-10-2018 A0127_04120 1c14d1c0900edb842c2b216ff48ac1f9 311 SMART SM00090 68 299 2.3E-87 T 23-10-2018 IPR000687 RIO kinase GO:0004674|GO:0005524 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6791226 A0127_04120 1c14d1c0900edb842c2b216ff48ac1f9 311 Pfam PF01163 RIO1 family 111 291 1.2E-49 T 23-10-2018 A0127_04120 1c14d1c0900edb842c2b216ff48ac1f9 311 SUPERFAMILY SSF56112 102 275 3.51E-26 T 23-10-2018 IPR011009 Protein kinase-like domain superfamily A0127_04120 1c14d1c0900edb842c2b216ff48ac1f9 311 SUPERFAMILY SSF46785 8 94 1.41E-24 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A0127_04120 1c14d1c0900edb842c2b216ff48ac1f9 311 Gene3D G3DSA:1.10.510.10 203 297 7.1E-17 T 23-10-2018 A0127_07030 3ea6fa8337766145e18dae660d94450f 257 SUPERFAMILY SSF110324 3 58 2.88E-13 T 23-10-2018 A0127_07030 3ea6fa8337766145e18dae660d94450f 257 SUPERFAMILY SSF54791 148 226 1.19E-17 T 23-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 A0127_07030 3ea6fa8337766145e18dae660d94450f 257 Hamap MF_00623 Exosome complex component Rrp4 [rrp4]. 7 232 40.091 T 23-10-2018 IPR023474 Exosome complex component Rrp4 GO:0000178|GO:0008143 A0127_07030 3ea6fa8337766145e18dae660d94450f 257 SMART SM00322 146 211 7.2E-8 T 23-10-2018 IPR004087 K Homology domain GO:0003676 A0127_07030 3ea6fa8337766145e18dae660d94450f 257 SUPERFAMILY SSF50249 59 152 1.11E-17 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A0127_07030 3ea6fa8337766145e18dae660d94450f 257 Gene3D G3DSA:2.40.50.100 1 57 2.1E-22 T 23-10-2018 A0127_07030 3ea6fa8337766145e18dae660d94450f 257 SMART SM00316 63 137 3.3E-8 T 23-10-2018 IPR022967 RNA-binding domain, S1 A0127_07030 3ea6fa8337766145e18dae660d94450f 257 Pfam PF14382 Exosome complex exonuclease RRP4 N-terminal region 11 46 1.1E-6 T 23-10-2018 IPR025721 Exosome complex component, N-terminal domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A0127_07030 3ea6fa8337766145e18dae660d94450f 257 Gene3D G3DSA:2.40.50.140 58 142 4.5E-21 T 23-10-2018 A0127_07030 3ea6fa8337766145e18dae660d94450f 257 Gene3D G3DSA:3.30.1370.10 149 234 8.6E-34 T 23-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 A0127_07030 3ea6fa8337766145e18dae660d94450f 257 Pfam PF15985 KH domain 149 195 8.4E-10 T 23-10-2018 IPR004088 K Homology domain, type 1 GO:0003723 A0127_02045 3ac1d2622b1418648125c1d4471a3b4f 216 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 155 195 5.9E-8 T 23-10-2018 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A0127_02045 3ac1d2622b1418648125c1d4471a3b4f 216 Gene3D G3DSA:3.40.30.10 1 144 9.8E-44 T 23-10-2018 A0127_02045 3ac1d2622b1418648125c1d4471a3b4f 216 Hamap MF_00401 Peroxiredoxin. 2 215 51.889 T 23-10-2018 IPR022915 Peroxiredoxin, TDXH subfamily GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 A0127_02045 3ac1d2622b1418648125c1d4471a3b4f 216 SUPERFAMILY SSF52833 1 215 2.8E-63 T 23-10-2018 IPR036249 Thioredoxin-like superfamily A0127_02045 3ac1d2622b1418648125c1d4471a3b4f 216 Gene3D G3DSA:3.30.1020.10 145 216 2.2E-35 T 23-10-2018 A0127_02045 3ac1d2622b1418648125c1d4471a3b4f 216 Pfam PF00578 AhpC/TSA family 4 134 8.7E-32 T 23-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A0127_02045 3ac1d2622b1418648125c1d4471a3b4f 216 PIRSF PIRSF000239 1 215 3.3E-70 T 23-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A0127_07385 73453dbb26e23f61c9547d667ef8be26 488 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 13 32 1.9E-9 T 23-10-2018 A0127_07385 73453dbb26e23f61c9547d667ef8be26 488 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 419 441 1.9E-9 T 23-10-2018 A0127_07385 73453dbb26e23f61c9547d667ef8be26 488 Pfam PF01946 Thi4 family 11 41 3.2E-7 T 23-10-2018 A0127_07385 73453dbb26e23f61c9547d667ef8be26 488 SUPERFAMILY SSF51905 11 463 2.16E-30 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A0127_07385 73453dbb26e23f61c9547d667ef8be26 488 Gene3D G3DSA:3.50.50.60 409 463 1.0E-5 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A0127_07385 73453dbb26e23f61c9547d667ef8be26 488 Gene3D G3DSA:3.50.50.60 135 236 2.1E-5 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A0127_07385 73453dbb26e23f61c9547d667ef8be26 488 Gene3D G3DSA:3.50.50.60 2 97 5.3E-20 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A0127_07385 73453dbb26e23f61c9547d667ef8be26 488 PIRSF PIRSF038984 135 467 2.8E-23 T 23-10-2018 IPR028348 FAD dependent protein A0127_07385 73453dbb26e23f61c9547d667ef8be26 488 PIRSF PIRSF038984 2 93 3.4E-10 T 23-10-2018 IPR028348 FAD dependent protein A0127_03620 2023aabbc4f8a43f25b2e9b63c0b6ec1 400 Pfam PF06819 Archaeal Peptidase A24 C-terminal Domain 256 364 7.3E-35 T 23-10-2018 IPR009639 Peptidase A24A-predicted, C-terminal archaea A0127_03620 2023aabbc4f8a43f25b2e9b63c0b6ec1 400 Gene3D G3DSA:1.20.120.1220 55 177 1.9E-14 T 23-10-2018 A0127_08720 78d8c44ba0aa442294d2ad8d95ba4c13 415 Gene3D G3DSA:3.30.1330.30 274 415 4.4E-44 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like A0127_08720 78d8c44ba0aa442294d2ad8d95ba4c13 415 SUPERFAMILY SSF53137 138 271 1.44E-44 T 23-10-2018 A0127_08720 78d8c44ba0aa442294d2ad8d95ba4c13 415 Gene3D G3DSA:3.30.960.10 1 130 1.8E-54 T 23-10-2018 IPR024049 Peptide Chain Release Factor eRF1/aRF1, N-terminal Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_08720 78d8c44ba0aa442294d2ad8d95ba4c13 415 Hamap MF_00424 Peptide chain release factor subunit 1 [prf1]. 18 415 45.818 T 23-10-2018 IPR020918 Peptide chain release factor aRF1 GO:0003747|GO:0005737|GO:0006415 A0127_08720 78d8c44ba0aa442294d2ad8d95ba4c13 415 TIGRFAM TIGR03676 aRF1/eRF1: peptide chain release factor 1, archaeal and eukaryotic forms 7 414 8.8E-184 T 23-10-2018 IPR004403 Peptide chain release factor eRF1/aRF1 GO:0003747|GO:0005737|GO:0006415 Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_08720 78d8c44ba0aa442294d2ad8d95ba4c13 415 Pfam PF03464 eRF1 domain 2 140 272 2.7E-50 T 23-10-2018 IPR005141 eRF1 domain 2 A0127_08720 78d8c44ba0aa442294d2ad8d95ba4c13 415 SUPERFAMILY SSF55315 272 414 2.94E-41 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like A0127_08720 78d8c44ba0aa442294d2ad8d95ba4c13 415 Gene3D G3DSA:3.30.420.60 131 271 1.1E-54 T 23-10-2018 A0127_08720 78d8c44ba0aa442294d2ad8d95ba4c13 415 SMART SM01194 1 135 9.1E-34 T 23-10-2018 IPR005140 eRF1 domain 1/Pelota-like A0127_08720 78d8c44ba0aa442294d2ad8d95ba4c13 415 SUPERFAMILY SSF55481 3 135 5.62E-49 T 23-10-2018 IPR024049 Peptide Chain Release Factor eRF1/aRF1, N-terminal Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_08720 78d8c44ba0aa442294d2ad8d95ba4c13 415 Pfam PF03465 eRF1 domain 3 276 414 9.7E-35 T 23-10-2018 IPR005142 eRF1 domain 3 A0127_08720 78d8c44ba0aa442294d2ad8d95ba4c13 415 Pfam PF03463 eRF1 domain 1 17 133 2.7E-9 T 23-10-2018 IPR005140 eRF1 domain 1/Pelota-like A0127_04490 c286944f1a9c567cb70ba1d0b5fd1f9d 237 SUPERFAMILY SSF52540 8 233 4.71E-42 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_04490 c286944f1a9c567cb70ba1d0b5fd1f9d 237 Gene3D G3DSA:3.40.50.300 7 235 3.1E-59 T 23-10-2018 A0127_04490 c286944f1a9c567cb70ba1d0b5fd1f9d 237 Pfam PF06745 KaiC 13 234 2.2E-49 T 23-10-2018 IPR014774 KaiC-like domain A0127_00890 e37ad4b05c994a19870b586141bff7ba 667 Gene3D G3DSA:3.40.50.970 4 192 1.1E-46 T 23-10-2018 A0127_00890 e37ad4b05c994a19870b586141bff7ba 667 Pfam PF00037 4Fe-4S binding domain 613 634 5.1E-7 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A0127_00890 e37ad4b05c994a19870b586141bff7ba 667 Gene3D G3DSA:3.30.70.20 581 644 8.0E-8 T 23-10-2018 A0127_00890 e37ad4b05c994a19870b586141bff7ba 667 PIRSF PIRSF006439 3 640 5.6E-190 T 23-10-2018 IPR017721 Indolepyruvate ferredoxin oxidoreductase, alpha subunit GO:0043805|GO:0055114 A0127_00890 e37ad4b05c994a19870b586141bff7ba 667 SUPERFAMILY SSF52922 254 315 4.91E-9 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A0127_00890 e37ad4b05c994a19870b586141bff7ba 667 Gene3D G3DSA:3.40.50.970 394 569 3.8E-20 T 23-10-2018 A0127_00890 e37ad4b05c994a19870b586141bff7ba 667 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 418 557 2.2E-24 T 23-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 A0127_00890 e37ad4b05c994a19870b586141bff7ba 667 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 619 630 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A0127_00890 e37ad4b05c994a19870b586141bff7ba 667 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 25 190 1.2E-12 T 23-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 A0127_00890 e37ad4b05c994a19870b586141bff7ba 667 SUPERFAMILY SSF52518 384 568 2.36E-27 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold A0127_00890 e37ad4b05c994a19870b586141bff7ba 667 SUPERFAMILY SSF54862 575 635 9.43E-10 T 23-10-2018 A0127_00890 e37ad4b05c994a19870b586141bff7ba 667 SUPERFAMILY SSF52518 16 191 3.48E-47 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold A0127_09715 6a643d432019533226f9f46115d5fab7 267 SUPERFAMILY SSF159659 2 259 6.41E-47 T 23-10-2018 A0127_09715 6a643d432019533226f9f46115d5fab7 267 Gene3D G3DSA:3.40.50.10900 1 244 8.2E-77 T 23-10-2018 IPR038389 Proteasome assembly chaperone 2 superfamily A0127_09715 6a643d432019533226f9f46115d5fab7 267 TIGRFAM TIGR00162 TIGR00162: TIGR00162 family protein 12 266 7.3E-74 T 23-10-2018 IPR004426 Conserved hypothetical protein CHP00062 A0127_09715 6a643d432019533226f9f46115d5fab7 267 Pfam PF09754 PAC2 family 19 242 1.0E-49 T 23-10-2018 IPR019151 Proteasome assembly chaperone 2 A0127_07160 a409d2229da3ffb7e30245c8ba4cdf00 600 SUPERFAMILY SSF142019 112 350 2.88E-97 T 23-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A0127_07160 a409d2229da3ffb7e30245c8ba4cdf00 600 SMART SM00928 439 484 1.1E-23 T 23-10-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A0127_07160 a409d2229da3ffb7e30245c8ba4cdf00 600 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 547 558 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A0127_07160 a409d2229da3ffb7e30245c8ba4cdf00 600 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 440 524 9.9E-32 T 23-10-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A0127_07160 a409d2229da3ffb7e30245c8ba4cdf00 600 SUPERFAMILY SSF140490 435 533 2.75E-36 T 23-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A0127_07160 a409d2229da3ffb7e30245c8ba4cdf00 600 Gene3D G3DSA:3.30.70.20 542 592 2.2E-14 T 23-10-2018 A0127_07160 a409d2229da3ffb7e30245c8ba4cdf00 600 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 158 329 4.4E-51 T 23-10-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A0127_07160 a409d2229da3ffb7e30245c8ba4cdf00 600 Gene3D G3DSA:3.40.30.10 5 97 2.7E-21 T 23-10-2018 A0127_07160 a409d2229da3ffb7e30245c8ba4cdf00 600 Pfam PF10531 SLBB domain 353 401 6.1E-9 T 23-10-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A0127_07160 a409d2229da3ffb7e30245c8ba4cdf00 600 Gene3D G3DSA:1.20.1440.230 437 538 1.2E-33 T 23-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A0127_07160 a409d2229da3ffb7e30245c8ba4cdf00 600 Gene3D G3DSA:3.10.20.600 342 436 7.0E-33 T 23-10-2018 A0127_07160 a409d2229da3ffb7e30245c8ba4cdf00 600 Gene3D G3DSA:3.40.50.11540 163 341 1.7E-84 T 23-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A0127_07160 a409d2229da3ffb7e30245c8ba4cdf00 600 SUPERFAMILY SSF54862 540 596 7.12E-16 T 23-10-2018 A0127_07160 a409d2229da3ffb7e30245c8ba4cdf00 600 Pfam PF13237 4Fe-4S dicluster domain 540 587 9.3E-8 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A0127_07160 a409d2229da3ffb7e30245c8ba4cdf00 600 SUPERFAMILY SSF52833 7 98 1.9E-20 T 23-10-2018 IPR036249 Thioredoxin-like superfamily A0127_07160 a409d2229da3ffb7e30245c8ba4cdf00 600 SUPERFAMILY SSF142984 351 434 1.83E-25 T 23-10-2018 A0127_08890 20504d7aeb98ec5cebea5862406f3cb4 154 Gene3D G3DSA:1.25.40.10 55 153 1.2E-15 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A0127_08890 20504d7aeb98ec5cebea5862406f3cb4 154 SUPERFAMILY SSF48452 23 145 1.43E-5 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A0127_10180 b573873268be1f152935de8b3e7b6e4e 569 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 228 250 - T 23-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 A0127_10180 b573873268be1f152935de8b3e7b6e4e 569 Pfam PF00069 Protein kinase domain 222 463 3.5E-48 T 23-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A0127_10180 b573873268be1f152935de8b3e7b6e4e 569 Gene3D G3DSA:1.10.510.10 213 496 3.7E-66 T 23-10-2018 A0127_10180 b573873268be1f152935de8b3e7b6e4e 569 SMART SM00220 222 471 6.2E-59 T 23-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A0127_10180 b573873268be1f152935de8b3e7b6e4e 569 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 332 344 - T 23-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 A0127_10180 b573873268be1f152935de8b3e7b6e4e 569 SUPERFAMILY SSF56112 214 465 1.31E-69 T 23-10-2018 IPR011009 Protein kinase-like domain superfamily A0127_01200 0275c3cb34473ae41e4c57c9f9f51c49 303 Pfam PF01751 Toprim domain 8 88 4.5E-8 T 23-10-2018 IPR006171 TOPRIM domain A0127_01200 0275c3cb34473ae41e4c57c9f9f51c49 303 SMART SM00493 5 84 1.0E-7 T 23-10-2018 IPR006171 TOPRIM domain A0127_01200 0275c3cb34473ae41e4c57c9f9f51c49 303 Gene3D G3DSA:3.40.1360.10 4 121 1.1E-6 T 23-10-2018 A0127_04970 e8e356a8d1b690d27be8e37ab8abd5f6 111 Gene3D G3DSA:1.10.8.10 70 109 4.0E-20 T 23-10-2018 A0127_04970 e8e356a8d1b690d27be8e37ab8abd5f6 111 Pfam PF01849 NAC domain 6 62 7.3E-12 T 23-10-2018 IPR002715 Nascent polypeptide-associated complex NAC domain A0127_04970 e8e356a8d1b690d27be8e37ab8abd5f6 111 Gene3D G3DSA:2.20.70.30 10 69 5.0E-22 T 23-10-2018 IPR038187 NAC A/B domain superfamily A0127_04970 e8e356a8d1b690d27be8e37ab8abd5f6 111 Hamap MF_00814 Nascent polypeptide-associated complex protein [nac]. 7 109 21.935 T 23-10-2018 IPR005231 Nascent polypeptide-associated complex (NAC), archaeal GO:0003723 A0127_04970 e8e356a8d1b690d27be8e37ab8abd5f6 111 SMART SM01407 6 66 9.1E-18 T 23-10-2018 IPR002715 Nascent polypeptide-associated complex NAC domain A0127_04970 e8e356a8d1b690d27be8e37ab8abd5f6 111 SUPERFAMILY SSF46934 70 110 8.93E-8 T 23-10-2018 IPR009060 UBA-like superfamily GO:0005515 A0127_04970 e8e356a8d1b690d27be8e37ab8abd5f6 111 TIGRFAM TIGR00264 TIGR00264: alpha-NAC homolog 3 110 1.9E-37 T 23-10-2018 IPR005231 Nascent polypeptide-associated complex (NAC), archaeal GO:0003723 A0127_06510 1426a9d2579bee48968a826cc20bd90e 390 Pfam PF00534 Glycosyl transferases group 1 214 350 2.3E-8 T 23-10-2018 IPR001296 Glycosyl transferase, family 1 A0127_06510 1426a9d2579bee48968a826cc20bd90e 390 Gene3D G3DSA:3.40.50.2000 1 190 7.7E-12 T 23-10-2018 A0127_06510 1426a9d2579bee48968a826cc20bd90e 390 Pfam PF09314 Domain of unknown function (DUF1972) 4 187 6.5E-19 T 23-10-2018 IPR015393 Domain of unknown function DUF1972 A0127_06510 1426a9d2579bee48968a826cc20bd90e 390 SUPERFAMILY SSF53756 4 386 1.83E-40 T 23-10-2018 A0127_06510 1426a9d2579bee48968a826cc20bd90e 390 Gene3D G3DSA:3.40.50.2000 202 385 8.6E-17 T 23-10-2018 A0127_01365 f6c7cbede44d1822131dfd041961e94c 188 Pfam PF06197 Protein of unknown function (DUF998) 10 180 1.4E-27 T 23-10-2018 IPR009339 Protein of unknown function DUF998 A0127_02440 ab19957d6574787b609d9b84fae84a6c 461 TIGRFAM TIGR02045 P_fruct_ADP: ADP-specific phosphofructokinase 13 457 1.3E-236 T 23-10-2018 IPR011790 ADP-specific phosphofructokinase, archaeal GO:0005737|GO:0006000|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.146|KEGG: 00030+2.7.1.146|KEGG: 00680+2.7.1.146|MetaCyc: PWY-6142 A0127_02440 ab19957d6574787b609d9b84fae84a6c 461 Gene3D G3DSA:3.40.1190.20 14 448 2.3E-157 T 23-10-2018 IPR029056 Ribokinase-like A0127_02440 ab19957d6574787b609d9b84fae84a6c 461 Hamap MF_00561 ADP-specific phosphofructokinase [pfkC]. 6 458 43.975 T 23-10-2018 IPR011790 ADP-specific phosphofructokinase, archaeal GO:0005737|GO:0006000|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.146|KEGG: 00030+2.7.1.146|KEGG: 00680+2.7.1.146|MetaCyc: PWY-6142 A0127_02440 ab19957d6574787b609d9b84fae84a6c 461 Gene3D G3DSA:3.30.1110.20 20 200 2.3E-157 T 23-10-2018 A0127_02440 ab19957d6574787b609d9b84fae84a6c 461 PIRSF PIRSF015883 1 458 1.3E-201 T 23-10-2018 IPR015990 ADP-specific phosphofructokinase/glucokinase, archaeal GO:0000287|GO:0006096|GO:0016773 A0127_02440 ab19957d6574787b609d9b84fae84a6c 461 Pfam PF04587 ADP-specific Phosphofructokinase/Glucokinase conserved region 14 449 6.4E-111 T 23-10-2018 IPR007666 ADP-specific phosphofructokinase/glucokinase GO:0005975|GO:0016773 Reactome: R-HSA-70171 A0127_02440 ab19957d6574787b609d9b84fae84a6c 461 SUPERFAMILY SSF53613 12 457 3.52E-156 T 23-10-2018 IPR029056 Ribokinase-like A0127_04925 ebbb8546980225b27319fbc5214e9ff2 174 ProDom PD068053 METHYLTRANSFERASE DNA METHYLATED-DNA--PROTEIN-CYSTEINE 6-O- O-6-METHYLGUANINE-DNA- REPAIR MGMT DAMAGE ALKYLTRANSFERASE METHYLGUANINE-DNA 1 96 3.0E-42 T 23-10-2018 IPR015236 Domain of unknown function DUF1938 GO:0005737 A0127_04925 ebbb8546980225b27319fbc5214e9ff2 174 SUPERFAMILY SSF46767 90 169 1.7E-23 T 23-10-2018 IPR036217 Methylated DNA-protein cysteine methyltransferase, DNA binding domain Reactome: R-HSA-5657655 A0127_04925 ebbb8546980225b27319fbc5214e9ff2 174 Pfam PF09153 Domain of unknown function (DUF1938) 1 85 3.1E-36 T 23-10-2018 IPR015236 Domain of unknown function DUF1938 GO:0005737 A0127_04925 ebbb8546980225b27319fbc5214e9ff2 174 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 91 169 9.7E-26 T 23-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 A0127_04925 ebbb8546980225b27319fbc5214e9ff2 174 Gene3D G3DSA:1.10.10.10 89 174 7.6E-35 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A0127_04925 ebbb8546980225b27319fbc5214e9ff2 174 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 139 145 - T 23-10-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 A0127_04925 ebbb8546980225b27319fbc5214e9ff2 174 SUPERFAMILY SSF53155 1 88 1.1E-32 T 23-10-2018 IPR036631 Methylated DNA-protein cysteine methyltransferase domain superfamily GO:0003908|GO:0006281 Reactome: R-HSA-5657655 A0127_04925 ebbb8546980225b27319fbc5214e9ff2 174 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 90 167 2.6E-29 T 23-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 A0127_04925 ebbb8546980225b27319fbc5214e9ff2 174 Hamap MF_00772 Methylated-DNA--protein-cysteine methyltransferase [ogt]. 18 168 34.568 T 23-10-2018 IPR023546 Methylated-DNA--protein-cysteine methyltransferase GO:0003824|GO:0006281 A0127_04925 ebbb8546980225b27319fbc5214e9ff2 174 Gene3D G3DSA:3.30.160.70 1 88 4.1E-50 T 23-10-2018 A0127_03435 e56292d1f10727d6bc6fbb76d5657d3a 481 Gene3D G3DSA:1.10.1060.10 4 150 1.6E-39 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 A0127_03435 e56292d1f10727d6bc6fbb76d5657d3a 481 SUPERFAMILY SSF51971 156 407 8.24E-72 T 23-10-2018 A0127_03435 e56292d1f10727d6bc6fbb76d5657d3a 481 Gene3D G3DSA:3.50.50.60 293 481 6.5E-31 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A0127_03435 e56292d1f10727d6bc6fbb76d5657d3a 481 Gene3D G3DSA:3.50.50.60 153 282 7.9E-38 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A0127_03435 e56292d1f10727d6bc6fbb76d5657d3a 481 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 158 456 1.3E-39 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A0127_03435 e56292d1f10727d6bc6fbb76d5657d3a 481 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 21 139 1.7E-38 T 23-10-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 A0127_03435 e56292d1f10727d6bc6fbb76d5657d3a 481 TIGRFAM TIGR01316 gltA: glutamate synthase (NADPH), homotetrameric 17 471 1.4E-210 T 23-10-2018 IPR006004 Glutamate synthase (NADPH), homotetrameric KEGG: 00195+1.18.1.2|MetaCyc: PWY-101 A0127_03435 e56292d1f10727d6bc6fbb76d5657d3a 481 SUPERFAMILY SSF46548 5 167 5.13E-33 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 A0127_03435 e56292d1f10727d6bc6fbb76d5657d3a 481 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 440 447 6.0E-18 T 23-10-2018 A0127_03435 e56292d1f10727d6bc6fbb76d5657d3a 481 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 158 180 6.0E-18 T 23-10-2018 A0127_03435 e56292d1f10727d6bc6fbb76d5657d3a 481 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 297 322 6.0E-18 T 23-10-2018 A0127_03435 e56292d1f10727d6bc6fbb76d5657d3a 481 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 400 414 6.0E-18 T 23-10-2018 A0127_03435 e56292d1f10727d6bc6fbb76d5657d3a 481 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 399 415 3.7E-24 T 23-10-2018 A0127_03435 e56292d1f10727d6bc6fbb76d5657d3a 481 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 425 447 3.7E-24 T 23-10-2018 A0127_03435 e56292d1f10727d6bc6fbb76d5657d3a 481 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 159 178 3.7E-24 T 23-10-2018 A0127_03435 e56292d1f10727d6bc6fbb76d5657d3a 481 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 297 315 3.7E-24 T 23-10-2018 A0127_02815 7d85f140c1023395584309fb611ea726 231 Pfam PF01973 Protein of unknown function DUF115 49 186 1.1E-28 T 23-10-2018 IPR002826 6-hydroxymethylpterin diphosphokinase MptE-like A0127_02815 7d85f140c1023395584309fb611ea726 231 SUPERFAMILY SSF63999 52 107 1.23E-8 T 23-10-2018 IPR036759 Thiamin pyrophosphokinase, catalytic domain superfamily GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 A0127_02815 7d85f140c1023395584309fb611ea726 231 Hamap MF_02131 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase [mptE]. 7 224 36.164 T 23-10-2018 IPR027510 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, MptE GO:0003848|GO:0005524 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 A0127_06145 74fc578b94ae9b6ec4552637cbe5d4c3 344 SUPERFAMILY SSF161098 115 320 1.96E-13 T 23-10-2018 IPR035906 MetI-like superfamily A0127_06145 74fc578b94ae9b6ec4552637cbe5d4c3 344 Gene3D G3DSA:1.10.3720.10 108 332 4.3E-16 T 23-10-2018 IPR035906 MetI-like superfamily A0127_06145 74fc578b94ae9b6ec4552637cbe5d4c3 344 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 137 337 6.8E-37 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A0127_09295 192f947fe9cce4b56c9fecf6c0d1eaa4 157 Hamap MF_00263 UPF0127 protein . 2 116 28.979 T 23-10-2018 IPR022906 Uncharacterised protein family UPF0127 A0127_09295 192f947fe9cce4b56c9fecf6c0d1eaa4 157 Pfam PF02643 Uncharacterized ACR, COG1430 15 114 2.6E-17 T 23-10-2018 IPR003795 Protein of unknown function DUF192 A0127_09295 192f947fe9cce4b56c9fecf6c0d1eaa4 157 Gene3D G3DSA:2.60.120.1140 1 123 9.8E-13 T 23-10-2018 IPR038695 Saro_0823-like superfamily A0127_00415 27035a2e97057b611dd624a1447ad318 234 Gene3D G3DSA:3.30.460.10 21 94 1.6E-7 T 23-10-2018 A0127_00415 27035a2e97057b611dd624a1447ad318 234 SUPERFAMILY SSF81301 20 72 2.69E-9 T 23-10-2018 A0127_00415 27035a2e97057b611dd624a1447ad318 234 Pfam PF01909 Nucleotidyltransferase domain 30 79 1.0E-7 T 23-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 A0127_00415 27035a2e97057b611dd624a1447ad318 234 PIRSF PIRSF005928 10 232 5.8E-103 T 23-10-2018 IPR009185 Predicted nucleotidyltransferase A0127_00065 5f4c2e314eb6b151c8d4ae1e5cbcb5bb 1188 Gene3D G3DSA:1.20.5.340 357 492 1.3E-6 T 23-10-2018 A0127_00065 5f4c2e314eb6b151c8d4ae1e5cbcb5bb 1188 Gene3D G3DSA:1.20.5.340 772 873 6.1E-9 T 23-10-2018 A0127_00065 5f4c2e314eb6b151c8d4ae1e5cbcb5bb 1188 Gene3D G3DSA:3.30.70.1620 581 658 1.1E-44 T 23-10-2018 A0127_00065 5f4c2e314eb6b151c8d4ae1e5cbcb5bb 1188 Gene3D G3DSA:3.40.50.300 2 234 1.1E-60 T 23-10-2018 A0127_00065 5f4c2e314eb6b151c8d4ae1e5cbcb5bb 1188 SUPERFAMILY SSF57997 298 503 3.73E-7 T 23-10-2018 A0127_00065 5f4c2e314eb6b151c8d4ae1e5cbcb5bb 1188 Pfam PF02463 RecF/RecN/SMC N terminal domain 3 1154 3.7E-77 T 23-10-2018 IPR003395 RecF/RecN/SMC, N-terminal A0127_00065 5f4c2e314eb6b151c8d4ae1e5cbcb5bb 1188 SUPERFAMILY SSF75553 480 676 4.18E-50 T 23-10-2018 IPR036277 SMCs flexible hinge superfamily GO:0005515|GO:0005524|GO:0005694|GO:0051276 A0127_00065 5f4c2e314eb6b151c8d4ae1e5cbcb5bb 1188 ProDom PD936484 POLYPROTEIN GLYCOPROTEIN M G2 TRANSMEMBRANE NONSTRUCTURAL MEMBRANE CONTAINS: PRECURSOR SIGNAL 295 937 1.0E-10 T 23-10-2018 A0127_00065 5f4c2e314eb6b151c8d4ae1e5cbcb5bb 1188 Pfam PF06470 SMC proteins Flexible Hinge Domain 520 631 4.2E-33 T 23-10-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 A0127_00065 5f4c2e314eb6b151c8d4ae1e5cbcb5bb 1188 Gene3D G3DSA:1.20.1060.20 506 662 1.1E-44 T 23-10-2018 A0127_00065 5f4c2e314eb6b151c8d4ae1e5cbcb5bb 1188 SUPERFAMILY SSF57997 668 821 2.75E-5 T 23-10-2018 A0127_00065 5f4c2e314eb6b151c8d4ae1e5cbcb5bb 1188 PIRSF PIRSF005719 1 1168 6.0E-281 T 23-10-2018 IPR024704 Structural maintenance of chromosomes protein A0127_00065 5f4c2e314eb6b151c8d4ae1e5cbcb5bb 1188 SUPERFAMILY SSF52540 1 1169 7.8E-57 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_00065 5f4c2e314eb6b151c8d4ae1e5cbcb5bb 1188 SMART SM00968 520 632 8.7E-43 T 23-10-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 A0127_00065 5f4c2e314eb6b151c8d4ae1e5cbcb5bb 1188 Hamap MF_01894 Chromosome partition protein Smc [smc]. 2 1163 21.563 T 23-10-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 A0127_00065 5f4c2e314eb6b151c8d4ae1e5cbcb5bb 1188 Gene3D G3DSA:1.20.5.340 668 771 5.4E-6 T 23-10-2018 A0127_00065 5f4c2e314eb6b151c8d4ae1e5cbcb5bb 1188 TIGRFAM TIGR02169 SMC_prok_A: chromosome segregation protein SMC 3 1161 0.0 T 23-10-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 A0127_00065 5f4c2e314eb6b151c8d4ae1e5cbcb5bb 1188 Gene3D G3DSA:3.40.50.300 1010 1181 1.0E-60 T 23-10-2018 A0127_00065 5f4c2e314eb6b151c8d4ae1e5cbcb5bb 1188 TIGRFAM TIGR02168 SMC_prok_B: chromosome segregation protein SMC 3 1161 1.1E-241 T 23-10-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 A0127_08085 26c3af4cba6164160707297807fb59ad 424 TIGRFAM TIGR04013 B12_SAM_MJ_1487: B12-binding domain/radical SAM domain protein, MJ_1487 family 4 392 5.9E-143 T 23-10-2018 IPR023980 Conserved hypothetical protein CHP04013, B12-binding/radical SAM-type A0127_08085 26c3af4cba6164160707297807fb59ad 424 Pfam PF04055 Radical SAM superfamily 168 338 1.2E-25 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A0127_08085 26c3af4cba6164160707297807fb59ad 424 SUPERFAMILY SSF102114 155 377 9.03E-40 T 23-10-2018 A0127_08085 26c3af4cba6164160707297807fb59ad 424 Gene3D G3DSA:3.80.30.20 163 389 9.4E-38 T 23-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe A0127_08085 26c3af4cba6164160707297807fb59ad 424 Pfam PF02310 B12 binding domain 17 112 5.4E-9 T 23-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 A0127_08085 26c3af4cba6164160707297807fb59ad 424 Gene3D G3DSA:3.40.50.280 3 128 3.4E-26 T 23-10-2018 A0127_08085 26c3af4cba6164160707297807fb59ad 424 SMART SM00729 164 382 5.6E-48 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A0127_01795 b6418c0cc0d2c17ca019aeac303cfbc8 173 SMART SM01118 1 166 1.5E-12 T 23-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 A0127_01795 b6418c0cc0d2c17ca019aeac303cfbc8 173 Pfam PF01928 CYTH domain 2 160 1.0E-25 T 23-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 A0127_01795 b6418c0cc0d2c17ca019aeac303cfbc8 173 Gene3D G3DSA:2.40.320.10 1 172 1.9E-49 T 23-10-2018 A0127_01795 b6418c0cc0d2c17ca019aeac303cfbc8 173 ProDom PD009560 CYCLASE ADENYLATE CYCLASE ADENYLYL CYAB LYASE CLASS CYAB-TYPE THERMOPHILIC MJ0240 2 141 3.0E-66 T 23-10-2018 A0127_01795 b6418c0cc0d2c17ca019aeac303cfbc8 173 SUPERFAMILY SSF55154 1 164 7.19E-39 T 23-10-2018 IPR033469 CYTH-like domain superfamily Reactome: R-HSA-196819 A0127_01795 b6418c0cc0d2c17ca019aeac303cfbc8 173 TIGRFAM TIGR00318 cyaB: putative adenylyl cyclase CyaB 2 165 3.2E-31 T 23-10-2018 IPR008173 Adenylyl cyclase CyaB KEGG: 00230+4.6.1.1 A0127_09955 aac80211cb964c98b3d1102fe8369b2f 332 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 266 322 1.9E-6 T 23-10-2018 IPR002831 Transcription regulator TrmB, N-terminal A0127_09955 aac80211cb964c98b3d1102fe8369b2f 332 Gene3D G3DSA:1.10.10.10 244 331 4.5E-10 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A0127_09955 aac80211cb964c98b3d1102fe8369b2f 332 SUPERFAMILY SSF46785 260 328 1.05E-11 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A0127_04575 902691856fb237f063b3701ecc09a6b2 341 PIRSF PIRSF004967 2 335 1.0E-82 T 23-10-2018 IPR035435 Diphthamide synthesis DHP1/DPH2, eukaryotes and archaea GO:0017183 MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 A0127_04575 902691856fb237f063b3701ecc09a6b2 341 Gene3D G3DSA:3.40.50.11840 5 98 1.0E-31 T 23-10-2018 A0127_04575 902691856fb237f063b3701ecc09a6b2 341 Gene3D G3DSA:3.40.50.11860 212 313 9.0E-35 T 23-10-2018 A0127_04575 902691856fb237f063b3701ecc09a6b2 341 Gene3D G3DSA:3.40.50.11850 100 208 2.1E-40 T 23-10-2018 A0127_04575 902691856fb237f063b3701ecc09a6b2 341 TIGRFAM TIGR00322 diphth2_R: diphthamide biosynthesis enzyme Dph1/Dph2 domain 7 313 3.9E-93 T 23-10-2018 IPR016435 Diphthamide synthesis DPH1/DPH2 MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 A0127_04575 902691856fb237f063b3701ecc09a6b2 341 TIGRFAM TIGR03682 arCOG04112: diphthamide biosynthesis enzyme Dph2 17 324 5.5E-114 T 23-10-2018 IPR022428 Diphthamide synthesis Dph2, archaea GO:0017183 MetaCyc: PWY-6482|MetaCyc: PWY-7546 A0127_04575 902691856fb237f063b3701ecc09a6b2 341 Pfam PF01866 Putative diphthamide synthesis protein 26 318 7.5E-79 T 23-10-2018 IPR016435 Diphthamide synthesis DPH1/DPH2 MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 A0127_03385 6b8e8240cea51fc4a7d280e1cda9c376 47 Pfam PF00096 Zinc finger, C2H2 type 18 41 8.9E-6 T 23-10-2018 IPR013087 Zinc finger C2H2-type GO:0003676 A0127_03385 6b8e8240cea51fc4a7d280e1cda9c376 47 ProSitePatterns PS00028 Zinc finger C2H2 type domain signature. 20 41 - T 23-10-2018 IPR013087 Zinc finger C2H2-type GO:0003676 A0127_03385 6b8e8240cea51fc4a7d280e1cda9c376 47 Gene3D G3DSA:3.30.160.60 15 43 2.3E-5 T 23-10-2018 A0127_03385 6b8e8240cea51fc4a7d280e1cda9c376 47 SMART SM00355 18 41 0.0018 T 23-10-2018 IPR013087 Zinc finger C2H2-type GO:0003676 A0127_03385 6b8e8240cea51fc4a7d280e1cda9c376 47 SUPERFAMILY SSF57667 13 43 6.45E-5 T 23-10-2018 IPR036236 Zinc finger C2H2 superfamily A0127_02615 b151885fc9f0e6ae6f57e6bd117d1726 170 Gene3D G3DSA:2.20.28.10 126 164 1.8E-19 T 23-10-2018 A0127_02615 b151885fc9f0e6ae6f57e6bd117d1726 170 SUPERFAMILY SSF88723 61 121 2.06E-7 T 23-10-2018 IPR029060 PIN-like domain superfamily A0127_02615 b151885fc9f0e6ae6f57e6bd117d1726 170 Gene3D G3DSA:3.40.50.1010 1 125 2.3E-42 T 23-10-2018 A0127_02615 b151885fc9f0e6ae6f57e6bd117d1726 170 SMART SM00670 9 107 1.4E-5 T 23-10-2018 IPR002716 PIN domain A0127_02615 b151885fc9f0e6ae6f57e6bd117d1726 170 Pfam PF17146 PIN domain of ribonuclease 14 94 1.9E-18 T 23-10-2018 IPR033411 Ribonuclease, PIN domain Reactome: R-HSA-6791226 A0127_07945 29ffc66dfb6d05f61aa86a62f6cf9621 683 Pfam PF03065 Glycosyl hydrolase family 57 6 365 2.0E-78 T 23-10-2018 IPR004300 Glycoside hydrolase family 57, N-terminal domain GO:0003824|GO:0005975 A0127_07945 29ffc66dfb6d05f61aa86a62f6cf9621 683 SUPERFAMILY SSF88688 416 532 4.58E-34 T 23-10-2018 IPR028995 Glycoside hydrolase families 57/38, central domain superfamily A0127_07945 29ffc66dfb6d05f61aa86a62f6cf9621 683 Gene3D G3DSA:3.20.110.10 1 416 3.3E-182 T 23-10-2018 IPR027291 Glycoside hydrolase 38, N-terminal domain superfamily A0127_07945 29ffc66dfb6d05f61aa86a62f6cf9621 683 SUPERFAMILY SSF88713 3 416 2.22E-125 T 23-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 A0127_07945 29ffc66dfb6d05f61aa86a62f6cf9621 683 Gene3D G3DSA:1.20.1430.10 417 562 2.8E-66 T 23-10-2018 IPR037090 Glycoside hydrolase families 57, central domain KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900 A0127_07945 29ffc66dfb6d05f61aa86a62f6cf9621 683 Pfam PF09210 Domain of unknown function (DUF1957) 427 528 2.0E-28 T 23-10-2018 IPR015293 Domain of unknown function DUF1957 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900 A0127_07945 29ffc66dfb6d05f61aa86a62f6cf9621 683 Pfam PF14520 Helix-hairpin-helix domain 630 679 1.1E-11 T 23-10-2018 A0127_07945 29ffc66dfb6d05f61aa86a62f6cf9621 683 SUPERFAMILY SSF47794 630 681 4.24E-9 T 23-10-2018 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 A0127_07945 29ffc66dfb6d05f61aa86a62f6cf9621 683 Gene3D G3DSA:1.10.150.20 629 683 7.5E-15 T 23-10-2018 A0127_05765 4eff007ac4e7151b0674b7a445d5332e 257 SUPERFAMILY SSF53167 1 255 6.15E-92 T 23-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 A0127_05765 4eff007ac4e7151b0674b7a445d5332e 257 Pfam PF01048 Phosphorylase superfamily 3 235 3.7E-49 T 23-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 A0127_05765 4eff007ac4e7151b0674b7a445d5332e 257 ProSitePatterns PS01240 Purine and other phosphorylases family 2 signature. 48 88 - T 23-10-2018 IPR018099 Purine phosphorylase, family 2, conserved site GO:0016763 A0127_05765 4eff007ac4e7151b0674b7a445d5332e 257 Hamap MF_01963 S-methyl-5'-thioadenosine phosphorylase [mtnP]. 2 257 44.852 T 23-10-2018 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112|Reactome: R-HSA-8950505 A0127_05765 4eff007ac4e7151b0674b7a445d5332e 257 TIGRFAM TIGR01694 MTAP: methylthioadenosine phosphorylase 3 237 5.0E-100 T 23-10-2018 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112|Reactome: R-HSA-8950505 A0127_05765 4eff007ac4e7151b0674b7a445d5332e 257 Gene3D G3DSA:3.40.50.1580 1 257 6.1E-103 T 23-10-2018 A0127_08905 29a866e50c4d01bdb7ba62373031a545 240 SUPERFAMILY SSF51735 5 239 1.75E-76 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A0127_08905 29a866e50c4d01bdb7ba62373031a545 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 4.1E-41 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A0127_08905 29a866e50c4d01bdb7ba62373031a545 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 203 223 4.1E-41 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A0127_08905 29a866e50c4d01bdb7ba62373031a545 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 4.1E-41 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A0127_08905 29a866e50c4d01bdb7ba62373031a545 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 4.1E-41 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A0127_08905 29a866e50c4d01bdb7ba62373031a545 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 4.1E-41 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A0127_08905 29a866e50c4d01bdb7ba62373031a545 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 4.1E-41 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A0127_08905 29a866e50c4d01bdb7ba62373031a545 240 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 236 1.2E-60 T 23-10-2018 A0127_08905 29a866e50c4d01bdb7ba62373031a545 240 Gene3D G3DSA:3.40.50.720 1 239 2.8E-79 T 23-10-2018 A0127_08905 29a866e50c4d01bdb7ba62373031a545 240 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 23-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A0127_08905 29a866e50c4d01bdb7ba62373031a545 240 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 8.0E-14 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A0127_08905 29a866e50c4d01bdb7ba62373031a545 240 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 8.0E-14 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A0127_08905 29a866e50c4d01bdb7ba62373031a545 240 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 8.0E-14 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A0127_07230 17c00cea684cefd70e893bbd882fdbf0 365 Gene3D G3DSA:1.10.132.50 34 353 1.3E-62 T 23-10-2018 A0127_07230 17c00cea684cefd70e893bbd882fdbf0 365 Gene3D G3DSA:1.20.1690.10 219 322 1.3E-62 T 23-10-2018 IPR035067 V-type ATPase subunit c Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A0127_07230 17c00cea684cefd70e893bbd882fdbf0 365 Pfam PF01992 ATP synthase (C/AC39) subunit 38 359 7.4E-67 T 23-10-2018 IPR002843 ATPase, V0 complex, c/d subunit Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A0127_07230 17c00cea684cefd70e893bbd882fdbf0 365 TIGRFAM TIGR02923 AhaC: ATP synthase A1, C subunit 31 361 7.4E-123 T 23-10-2018 IPR014272 ATPase, V0 complex, c subunit GO:0033179|GO:0046961 A0127_07230 17c00cea684cefd70e893bbd882fdbf0 365 Hamap MF_00314 V-type ATP synthase subunit C [atpC]. 30 362 25.065 T 23-10-2018 IPR014272 ATPase, V0 complex, c subunit GO:0033179|GO:0046961 A0127_07230 17c00cea684cefd70e893bbd882fdbf0 365 SUPERFAMILY SSF103486 34 362 1.05E-79 T 23-10-2018 IPR036079 V-type ATP synthase subunit C-like Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A0127_07230 17c00cea684cefd70e893bbd882fdbf0 365 Gene3D G3DSA:1.20.1690.10 111 208 1.3E-62 T 23-10-2018 IPR035067 V-type ATPase subunit c Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A0127_01185 2273e478d2559ac3b2a8be232ed04f73 451 Gene3D G3DSA:1.10.10.10 235 337 2.8E-6 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A0127_01185 2273e478d2559ac3b2a8be232ed04f73 451 Gene3D G3DSA:3.40.50.300 1 167 6.6E-26 T 23-10-2018 A0127_01185 2273e478d2559ac3b2a8be232ed04f73 451 Pfam PF03008 Archaea bacterial proteins of unknown function 312 399 3.7E-16 T 23-10-2018 IPR004256 Domain of unknown function DUF234, DEXX-box ATPase C-terminal A0127_01185 2273e478d2559ac3b2a8be232ed04f73 451 SUPERFAMILY SSF46785 243 354 6.07E-9 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A0127_01185 2273e478d2559ac3b2a8be232ed04f73 451 Pfam PF01637 ATPase domain predominantly from Archaea 3 201 1.5E-13 T 23-10-2018 IPR011579 ATPase domain GO:0005524 A0127_01185 2273e478d2559ac3b2a8be232ed04f73 451 SUPERFAMILY SSF52540 1 205 7.14E-31 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_02220 37cddb628568ed9b8c2f77b9b10eaa87 386 SUPERFAMILY SSF55821 2 185 1.83E-44 T 23-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily A0127_02220 37cddb628568ed9b8c2f77b9b10eaa87 386 TIGRFAM TIGR00505 ribA: GTP cyclohydrolase II 198 382 2.2E-69 T 23-10-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 A0127_02220 37cddb628568ed9b8c2f77b9b10eaa87 386 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 5 185 3.2E-41 T 23-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A0127_02220 37cddb628568ed9b8c2f77b9b10eaa87 386 SUPERFAMILY SSF142695 193 360 1.07E-58 T 23-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 A0127_02220 37cddb628568ed9b8c2f77b9b10eaa87 386 Pfam PF00925 GTP cyclohydrolase II 199 358 4.1E-67 T 23-10-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 A0127_02220 37cddb628568ed9b8c2f77b9b10eaa87 386 Gene3D G3DSA:3.90.870.10 2 193 1.8E-42 T 23-10-2018 A0127_02220 37cddb628568ed9b8c2f77b9b10eaa87 386 Hamap MF_00179 GTP cyclohydrolase-2 [ribA]. 192 384 37.981 T 23-10-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 A0127_02220 37cddb628568ed9b8c2f77b9b10eaa87 386 PIRSF PIRSF001259 1 386 7.1E-128 T 23-10-2018 A0127_02220 37cddb628568ed9b8c2f77b9b10eaa87 386 Gene3D G3DSA:3.40.50.10990 194 358 1.4E-68 T 23-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 A0127_02720 1fb5872958208192940131d7ef3bd727 102 SUPERFAMILY SSF54999 3 100 3.92E-29 T 23-10-2018 IPR036838 Ribosomal protein S10 domain superfamily A0127_02720 1fb5872958208192940131d7ef3bd727 102 SMART SM01403 5 99 1.5E-41 T 23-10-2018 IPR027486 Ribosomal protein S10 domain A0127_02720 1fb5872958208192940131d7ef3bd727 102 Pfam PF00338 Ribosomal protein S10p/S20e 5 98 1.2E-27 T 23-10-2018 IPR027486 Ribosomal protein S10 domain A0127_02720 1fb5872958208192940131d7ef3bd727 102 Gene3D G3DSA:3.30.70.600 1 101 4.6E-35 T 23-10-2018 IPR036838 Ribosomal protein S10 domain superfamily A0127_02720 1fb5872958208192940131d7ef3bd727 102 PRINTS PR00971 Ribosomal protein S10 family signature 3 16 1.6E-16 T 23-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_02720 1fb5872958208192940131d7ef3bd727 102 PRINTS PR00971 Ribosomal protein S10 family signature 60 74 1.6E-16 T 23-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_02720 1fb5872958208192940131d7ef3bd727 102 PRINTS PR00971 Ribosomal protein S10 family signature 38 53 1.6E-16 T 23-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_02720 1fb5872958208192940131d7ef3bd727 102 ProSitePatterns PS00361 Ribosomal protein S10 signature. 27 42 - T 23-10-2018 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_02720 1fb5872958208192940131d7ef3bd727 102 TIGRFAM TIGR01046 uS10_euk_arch: ribosomal protein uS10 2 100 1.0E-50 T 23-10-2018 IPR005729 Ribosomal protein S10, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_02720 1fb5872958208192940131d7ef3bd727 102 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 1 100 24.692 T 23-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_06775 68fa6c45c6eaa46f44b6243b9c6a7e09 63 SUPERFAMILY SSF54862 3 60 2.59E-15 T 23-10-2018 A0127_06775 68fa6c45c6eaa46f44b6243b9c6a7e09 63 Gene3D G3DSA:3.30.70.20 3 62 2.7E-23 T 23-10-2018 A0127_06775 68fa6c45c6eaa46f44b6243b9c6a7e09 63 PRINTS PR00352 3Fe-4S ferredoxin signature 7 18 5.2E-10 T 23-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 A0127_06775 68fa6c45c6eaa46f44b6243b9c6a7e09 63 PRINTS PR00352 3Fe-4S ferredoxin signature 18 28 5.2E-10 T 23-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 A0127_06775 68fa6c45c6eaa46f44b6243b9c6a7e09 63 PRINTS PR00352 3Fe-4S ferredoxin signature 46 58 5.2E-10 T 23-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 A0127_06775 68fa6c45c6eaa46f44b6243b9c6a7e09 63 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 7 59 2.4E-17 T 23-10-2018 A0127_02345 d5450662ebf411b4f6ed3eb6c250ef4d 244 Pfam PF00491 Arginase family 56 230 3.1E-17 T 23-10-2018 IPR006035 Ureohydrolase GO:0046872 A0127_02345 d5450662ebf411b4f6ed3eb6c250ef4d 244 SUPERFAMILY SSF52768 56 235 8.46E-26 T 23-10-2018 IPR023696 Ureohydrolase domain superfamily A0127_02345 d5450662ebf411b4f6ed3eb6c250ef4d 244 PIRSF PIRSF036979 35 236 8.0E-16 T 23-10-2018 IPR006035 Ureohydrolase GO:0046872 A0127_02345 d5450662ebf411b4f6ed3eb6c250ef4d 244 Gene3D G3DSA:3.40.800.10 36 243 2.2E-18 T 23-10-2018 A0127_01920 79f919705a3ae62a877538afc2864865 177 Gene3D G3DSA:3.10.580.10 1 176 1.1E-42 T 23-10-2018 A0127_01920 79f919705a3ae62a877538afc2864865 177 Pfam PF00571 CBS domain 72 125 3.1E-13 T 23-10-2018 IPR000644 CBS domain A0127_01920 79f919705a3ae62a877538afc2864865 177 Pfam PF00571 CBS domain 6 60 5.4E-13 T 23-10-2018 IPR000644 CBS domain A0127_01920 79f919705a3ae62a877538afc2864865 177 SMART SM00116 79 126 1.0E-8 T 23-10-2018 IPR000644 CBS domain A0127_01920 79f919705a3ae62a877538afc2864865 177 SMART SM00116 13 61 2.2E-9 T 23-10-2018 IPR000644 CBS domain A0127_01920 79f919705a3ae62a877538afc2864865 177 SUPERFAMILY SSF54631 3 134 4.04E-33 T 23-10-2018 A0127_00395 c512030ea362442f82c0baba1f61169a 344 Gene3D G3DSA:3.40.50.2000 1 173 4.7E-44 T 23-10-2018 A0127_00395 c512030ea362442f82c0baba1f61169a 344 Gene3D G3DSA:3.40.50.2000 174 325 7.8E-32 T 23-10-2018 A0127_00395 c512030ea362442f82c0baba1f61169a 344 Pfam PF13439 Glycosyltransferase Family 4 14 168 3.2E-34 T 23-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 A0127_00395 c512030ea362442f82c0baba1f61169a 344 Pfam PF00534 Glycosyl transferases group 1 173 321 1.1E-24 T 23-10-2018 IPR001296 Glycosyl transferase, family 1 A0127_00395 c512030ea362442f82c0baba1f61169a 344 SUPERFAMILY SSF53756 5 343 9.42E-81 T 23-10-2018 A0127_01960 0bdf5d343f9571eda94f93f8c669c1e7 536 Gene3D G3DSA:3.90.870.20 330 535 2.3E-73 T 23-10-2018 IPR038152 Carbamoyltransferase, C-terminal domain superfamily A0127_01960 0bdf5d343f9571eda94f93f8c669c1e7 536 SUPERFAMILY SSF53067 11 313 9.71E-12 T 23-10-2018 A0127_01960 0bdf5d343f9571eda94f93f8c669c1e7 536 Pfam PF02543 Carbamoyltransferase N-terminus 2 68 6.3E-9 T 23-10-2018 IPR003696 Carbamoyltransferase GO:0003824|GO:0009058 A0127_01960 0bdf5d343f9571eda94f93f8c669c1e7 536 Pfam PF02543 Carbamoyltransferase N-terminus 87 312 9.7E-38 T 23-10-2018 IPR003696 Carbamoyltransferase GO:0003824|GO:0009058 A0127_01960 0bdf5d343f9571eda94f93f8c669c1e7 536 Gene3D G3DSA:3.30.420.350 95 305 4.0E-65 T 23-10-2018 A0127_01960 0bdf5d343f9571eda94f93f8c669c1e7 536 Gene3D G3DSA:3.30.420.40 9 312 4.0E-65 T 23-10-2018 A0127_01960 0bdf5d343f9571eda94f93f8c669c1e7 536 Pfam PF16861 Carbamoyltransferase C-terminus 366 536 1.3E-61 T 23-10-2018 IPR031730 Carbamoyltransferase, C-terminal A0127_07900 9a37f494d6201f45ff76be0edf316377 194 Pfam PF00827 Ribosomal L15 2 189 3.7E-89 T 23-10-2018 IPR000439 Ribosomal protein L15e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_07900 9a37f494d6201f45ff76be0edf316377 194 Hamap MF_00256 50S ribosomal protein L15e [rpl15e]. 1 193 43.125 T 23-10-2018 IPR020926 Ribosomal protein L15e, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 A0127_07900 9a37f494d6201f45ff76be0edf316377 194 SMART SM01384 2 191 9.2E-133 T 23-10-2018 IPR000439 Ribosomal protein L15e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_07900 9a37f494d6201f45ff76be0edf316377 194 SUPERFAMILY SSF54189 1 191 5.76E-87 T 23-10-2018 IPR012678 Ribosomal protein L23/L15e core domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 A0127_07900 9a37f494d6201f45ff76be0edf316377 194 Gene3D G3DSA:3.40.1120.10 1 193 5.3E-90 T 23-10-2018 IPR024794 Ribosomal protein L15e core domain superfamily GO:0003735|GO:0005840 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_07900 9a37f494d6201f45ff76be0edf316377 194 ProSitePatterns PS01194 Ribosomal protein L15e signature. 46 69 - T 23-10-2018 IPR020925 Ribosomal protein L15e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_07935 986a9913993f8e8f9d7cddd66a6653c7 650 Pfam PF05670 Domain of unknown function (DUF814) 455 553 6.5E-27 T 23-10-2018 IPR008532 Domain of unknown function DUF814 A0127_07935 986a9913993f8e8f9d7cddd66a6653c7 650 Pfam PF05833 Fibronectin-binding protein A N-terminus (FbpA) 7 436 3.6E-86 T 23-10-2018 A0127_07935 986a9913993f8e8f9d7cddd66a6653c7 650 SUPERFAMILY SSF46946 182 222 7.26E-5 T 23-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 A0127_07935 986a9913993f8e8f9d7cddd66a6653c7 650 Gene3D G3DSA:2.30.310.10 5 150 3.1E-32 T 23-10-2018 A0127_07610 ef2a7dfdbd940bd4f4295116f800bd5b 193 TIGRFAM TIGR02173 cyt_kin_arch: putative cytidylate kinase 6 175 4.0E-62 T 23-10-2018 IPR011892 Cytidylate kinase, putative GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 A0127_07610 ef2a7dfdbd940bd4f4295116f800bd5b 193 SUPERFAMILY SSF52540 7 175 1.59E-22 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_07610 ef2a7dfdbd940bd4f4295116f800bd5b 193 Pfam PF13189 Cytidylate kinase-like family 7 160 3.0E-25 T 23-10-2018 A0127_07610 ef2a7dfdbd940bd4f4295116f800bd5b 193 Hamap MF_00239 Cytidylate kinase [cmk]. 6 178 47.69 T 23-10-2018 IPR011892 Cytidylate kinase, putative GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 A0127_07610 ef2a7dfdbd940bd4f4295116f800bd5b 193 Gene3D G3DSA:3.40.50.300 2 177 2.1E-45 T 23-10-2018 A0127_01410 34855d01570db01964fb1f5313251ef4 384 Gene3D G3DSA:2.130.10.10 26 325 4.7E-20 T 23-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 A0127_01410 34855d01570db01964fb1f5313251ef4 384 SUPERFAMILY SSF50998 61 319 1.06E-25 T 23-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily A0127_01410 34855d01570db01964fb1f5313251ef4 384 Pfam PF13360 PQQ-like domain 139 271 8.0E-7 T 23-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat A0127_00030 118e49deec2f2be94cc4f78963f8d859 254 TIGRFAM TIGR01769 GGGP: phosphoglycerol geranylgeranyltransferase 21 227 1.1E-82 T 23-10-2018 IPR010946 Geranylgeranylglyceryl phosphate synthase GO:0000287|GO:0005737|GO:0006650|GO:0047294 KEGG: 00564+2.5.1.41|MetaCyc: PWY-6349 A0127_00030 118e49deec2f2be94cc4f78963f8d859 254 SUPERFAMILY SSF51395 18 236 3.66E-49 T 23-10-2018 A0127_00030 118e49deec2f2be94cc4f78963f8d859 254 Hamap MF_00112 Geranylgeranylglyceryl phosphate synthase [pcrB]. 14 246 35.954 T 23-10-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 A0127_00030 118e49deec2f2be94cc4f78963f8d859 254 Pfam PF01884 PcrB family 15 238 3.2E-67 T 23-10-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 A0127_00030 118e49deec2f2be94cc4f78963f8d859 254 Gene3D G3DSA:3.20.20.390 3 252 1.1E-100 T 23-10-2018 IPR038597 GGGP/HepGP synthase superfamily A0127_00030 118e49deec2f2be94cc4f78963f8d859 254 TIGRFAM TIGR01768 GGGP-family: geranylgeranylglyceryl phosphate synthase family protein 20 240 3.0E-78 T 23-10-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 A0127_05115 b1152af454874f92323e6655c88c5e7e 278 Gene3D G3DSA:3.40.50.620 148 278 1.3E-25 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A0127_05115 b1152af454874f92323e6655c88c5e7e 278 Pfam PF00582 Universal stress protein family 153 276 1.0E-15 T 23-10-2018 IPR006016 UspA A0127_05115 b1152af454874f92323e6655c88c5e7e 278 Pfam PF00582 Universal stress protein family 1 133 6.6E-21 T 23-10-2018 IPR006016 UspA A0127_05115 b1152af454874f92323e6655c88c5e7e 278 PRINTS PR01438 Universal stress protein signature 236 248 2.5E-17 T 23-10-2018 IPR006015 Universal stress protein A A0127_05115 b1152af454874f92323e6655c88c5e7e 278 PRINTS PR01438 Universal stress protein signature 2 20 2.5E-17 T 23-10-2018 IPR006015 Universal stress protein A A0127_05115 b1152af454874f92323e6655c88c5e7e 278 PRINTS PR01438 Universal stress protein signature 254 276 2.5E-17 T 23-10-2018 IPR006015 Universal stress protein A A0127_05115 b1152af454874f92323e6655c88c5e7e 278 Gene3D G3DSA:3.40.50.620 1 142 3.7E-29 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A0127_05115 b1152af454874f92323e6655c88c5e7e 278 SUPERFAMILY SSF52402 151 276 2.51E-22 T 23-10-2018 A0127_05115 b1152af454874f92323e6655c88c5e7e 278 SUPERFAMILY SSF52402 1 133 1.26E-26 T 23-10-2018 A0127_09655 efb2bfc91a714c8781d002508706c3bf 619 Gene3D G3DSA:3.60.9.10 1 209 3.9E-91 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily A0127_09655 efb2bfc91a714c8781d002508706c3bf 619 Gene3D G3DSA:1.10.599.10 237 605 7.1E-133 T 23-10-2018 IPR013985 Aldehyde ferredoxin oxidoreductase, domain 3 GO:0016625|GO:0051536|GO:0055114 KEGG: 00030+1.2.7.5 A0127_09655 efb2bfc91a714c8781d002508706c3bf 619 SUPERFAMILY SSF48310 211 618 7.98E-128 T 23-10-2018 IPR036021 Aldehyde ferredoxin oxidoreductase-like, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 A0127_09655 efb2bfc91a714c8781d002508706c3bf 619 SMART SM00790 4 205 1.9E-118 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 A0127_09655 efb2bfc91a714c8781d002508706c3bf 619 Gene3D G3DSA:1.10.569.10 239 417 7.1E-133 T 23-10-2018 IPR013984 Aldehyde ferredoxin oxidoreductase, domain 2 A0127_09655 efb2bfc91a714c8781d002508706c3bf 619 SUPERFAMILY SSF56228 1 209 5.36E-74 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily A0127_09655 efb2bfc91a714c8781d002508706c3bf 619 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 6 204 5.3E-78 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 A0127_09655 efb2bfc91a714c8781d002508706c3bf 619 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 218 605 2.9E-111 T 23-10-2018 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 A0127_09815 9bd880ad6adec9dae380bb1e3df764fb 906 SMART SM00663 211 515 4.9E-205 T 23-10-2018 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A0127_09815 9bd880ad6adec9dae380bb1e3df764fb 906 Gene3D G3DSA:2.40.40.20 311 482 3.5E-80 T 23-10-2018 A0127_09815 9bd880ad6adec9dae380bb1e3df764fb 906 Pfam PF04998 RNA polymerase Rpb1, domain 5 811 876 4.1E-29 T 23-10-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A0127_09815 9bd880ad6adec9dae380bb1e3df764fb 906 SUPERFAMILY SSF64484 4 887 0.0 T 23-10-2018 A0127_09815 9bd880ad6adec9dae380bb1e3df764fb 906 Gene3D G3DSA:1.10.132.30 672 813 4.4E-45 T 23-10-2018 IPR038120 RNA polymerase Rpb1, funnel domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A0127_09815 9bd880ad6adec9dae380bb1e3df764fb 906 Gene3D G3DSA:1.10.274.100 491 671 4.2E-66 T 23-10-2018 A0127_09815 9bd880ad6adec9dae380bb1e3df764fb 906 Pfam PF00623 RNA polymerase Rpb1, domain 2 321 487 1.6E-73 T 23-10-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A0127_09815 9bd880ad6adec9dae380bb1e3df764fb 906 TIGRFAM TIGR02390 RNA_pol_rpoA1: DNA-directed RNA polymerase subunit A' 5 894 0.0 T 23-10-2018 IPR012758 DNA-directed RNA polymerase subunit A' (Rpo1N) GO:0003677|GO:0003899|GO:0006351|GO:0008270 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A0127_09815 9bd880ad6adec9dae380bb1e3df764fb 906 Pfam PF04983 RNA polymerase Rpb1, domain 3 490 672 5.8E-38 T 23-10-2018 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A0127_09815 9bd880ad6adec9dae380bb1e3df764fb 906 Gene3D G3DSA:2.20.25.410 850 900 2.3E-22 T 23-10-2018 A0127_09815 9bd880ad6adec9dae380bb1e3df764fb 906 Gene3D G3DSA:1.20.120.1280 1 123 9.3E-32 T 23-10-2018 A0127_09815 9bd880ad6adec9dae380bb1e3df764fb 906 Gene3D G3DSA:1.20.120.1280 235 284 2.3E-11 T 23-10-2018 A0127_09815 9bd880ad6adec9dae380bb1e3df764fb 906 Gene3D G3DSA:3.30.1490.180 354 418 3.5E-80 T 23-10-2018 A0127_09815 9bd880ad6adec9dae380bb1e3df764fb 906 Pfam PF04997 RNA polymerase Rpb1, domain 1 6 319 4.9E-108 T 23-10-2018 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A0127_09815 9bd880ad6adec9dae380bb1e3df764fb 906 Pfam PF05000 RNA polymerase Rpb1, domain 4 698 804 1.0E-31 T 23-10-2018 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A0127_03555 0e42fe143c8e29ac247d281a0303927c 278 Pfam PF02475 Met-10+ like-protein 29 223 4.7E-70 T 23-10-2018 IPR030382 SAM-dependent methyltransferase TRM5/TYW2-type Reactome: R-HSA-6782861 A0127_03555 0e42fe143c8e29ac247d281a0303927c 278 Hamap MF_01922 tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase [taw2]. 26 276 42.282 T 23-10-2018 IPR030867 tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase GO:0006400|GO:0016765 MetaCyc: PWY-7286 A0127_03555 0e42fe143c8e29ac247d281a0303927c 278 Gene3D G3DSA:3.40.50.150 87 278 4.3E-58 T 23-10-2018 A0127_03555 0e42fe143c8e29ac247d281a0303927c 278 Gene3D G3DSA:3.30.300.110 19 86 1.5E-29 T 23-10-2018 A0127_03555 0e42fe143c8e29ac247d281a0303927c 278 SUPERFAMILY SSF53335 19 277 3.63E-70 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A0127_07625 688228f4daeb6b6a58067bd0fbcaf17b 73 Gene3D G3DSA:3.30.160.250 3 66 1.3E-10 T 23-10-2018 A0127_07625 688228f4daeb6b6a58067bd0fbcaf17b 73 SUPERFAMILY SSF143100 6 56 3.4E-12 T 23-10-2018 IPR035069 TTHA1013/TTHA0281-like A0127_09660 743e244491a7ee815b8d7152f4e7f0a4 319 SUPERFAMILY SSF48452 35 228 2.11E-11 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A0127_09660 743e244491a7ee815b8d7152f4e7f0a4 319 Gene3D G3DSA:1.25.40.10 6 230 1.4E-11 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A0127_09660 743e244491a7ee815b8d7152f4e7f0a4 319 SMART SM00028 121 154 0.0053 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A0127_09660 743e244491a7ee815b8d7152f4e7f0a4 319 SMART SM00028 81 114 440.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A0127_05455 097e28ccd4d8a390284d7e571ca49aac 162 Gene3D G3DSA:3.40.1520.10 1 162 1.0E-72 T 23-10-2018 IPR036902 Ta1353-like superfamily A0127_05455 097e28ccd4d8a390284d7e571ca49aac 162 Pfam PF04008 Adenosine specific kinase 7 159 1.3E-62 T 23-10-2018 IPR007153 Adenosine specific kinase A0127_05455 097e28ccd4d8a390284d7e571ca49aac 162 SUPERFAMILY SSF103165 2 160 3.4E-60 T 23-10-2018 IPR036902 Ta1353-like superfamily A0127_00605 05f35ad039214199badbbf8c78f368e6 581 SUPERFAMILY SSF81585 511 581 1.05E-10 T 23-10-2018 A0127_00605 05f35ad039214199badbbf8c78f368e6 581 SMART SM00729 200 450 2.5E-35 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A0127_00605 05f35ad039214199badbbf8c78f368e6 581 Gene3D G3DSA:3.80.30.20 200 457 3.8E-27 T 23-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe A0127_00605 05f35ad039214199badbbf8c78f368e6 581 Pfam PF04055 Radical SAM superfamily 204 403 1.5E-24 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A0127_00605 05f35ad039214199badbbf8c78f368e6 581 SUPERFAMILY SSF102114 188 447 5.76E-28 T 23-10-2018 A0127_00605 05f35ad039214199badbbf8c78f368e6 581 Gene3D G3DSA:1.10.150.320 518 580 1.4E-8 T 23-10-2018 A0127_00605 05f35ad039214199badbbf8c78f368e6 581 Pfam PF12836 Helix-hairpin-helix motif 525 568 5.6E-7 T 23-10-2018 A0127_08445 0aed393d4806b4f49f1f016cc6551c1a 631 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 576 587 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A0127_08445 0aed393d4806b4f49f1f016cc6551c1a 631 SUPERFAMILY SSF54862 558 623 9.9E-15 T 23-10-2018 A0127_08445 0aed393d4806b4f49f1f016cc6551c1a 631 SMART SM00359 133 207 1.5E-16 T 23-10-2018 IPR002478 PUA domain GO:0003723 A0127_08445 0aed393d4806b4f49f1f016cc6551c1a 631 Pfam PF12838 4Fe-4S dicluster domain 576 618 1.8E-8 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A0127_08445 0aed393d4806b4f49f1f016cc6551c1a 631 Gene3D G3DSA:2.30.130.10 130 205 1.2E-16 T 23-10-2018 IPR036974 PUA domain superfamily GO:0003723 A0127_08445 0aed393d4806b4f49f1f016cc6551c1a 631 SUPERFAMILY SSF88697 132 204 5.47E-19 T 23-10-2018 IPR015947 PUA-like superfamily A0127_08445 0aed393d4806b4f49f1f016cc6551c1a 631 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 253 429 8.0E-45 T 23-10-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824 Reactome: R-HSA-196843 A0127_08445 0aed393d4806b4f49f1f016cc6551c1a 631 Pfam PF01472 PUA domain 134 204 6.1E-18 T 23-10-2018 IPR002478 PUA domain GO:0003723 A0127_08445 0aed393d4806b4f49f1f016cc6551c1a 631 Gene3D G3DSA:3.30.70.20 570 622 9.7E-11 T 23-10-2018 A0127_08445 0aed393d4806b4f49f1f016cc6551c1a 631 Gene3D G3DSA:3.40.50.620 218 441 6.5E-49 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A0127_08445 0aed393d4806b4f49f1f016cc6551c1a 631 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 607 618 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A0127_08445 0aed393d4806b4f49f1f016cc6551c1a 631 TIGRFAM TIGR00451 unchar_dom_2: uncharacterized domain 2 93 201 7.5E-11 T 23-10-2018 IPR004521 Uncharacterised domain CHP00451 GO:0003723 A0127_08445 0aed393d4806b4f49f1f016cc6551c1a 631 SUPERFAMILY SSF52402 223 417 2.43E-45 T 23-10-2018 A0127_03040 ad60c31a0642f466aa1cc91796f57332 136 Pfam PF02566 OsmC-like protein 31 118 9.5E-16 T 23-10-2018 IPR003718 OsmC/Ohr family A0127_03040 ad60c31a0642f466aa1cc91796f57332 136 SUPERFAMILY SSF82784 13 132 7.33E-31 T 23-10-2018 IPR036102 OsmC/Ohr superfamily A0127_03040 ad60c31a0642f466aa1cc91796f57332 136 Gene3D G3DSA:3.30.300.20 3 133 1.1E-33 T 23-10-2018 IPR015946 K homology domain-like, alpha/beta A0127_01420 26a0fc64b82ea4575655a656f10cb9a6 239 Pfam PF01061 ABC-2 type transporter 6 204 9.5E-27 T 23-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 A0127_01420 26a0fc64b82ea4575655a656f10cb9a6 239 PIRSF PIRSF006648 2 238 6.9E-28 T 23-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A0127_04190 c140135e06b2e4f857f093aebdeb3e49 160 Pfam PF12689 Acid Phosphatase 1 63 2.9E-7 T 23-10-2018 IPR010036 Magnesium-dependent phosphatase-1, eukaryotic/archaeal-type GO:0016791 A0127_04190 c140135e06b2e4f857f093aebdeb3e49 160 TIGRFAM TIGR01685 MDP-1: magnesium-dependent phosphatase-1 2 150 1.2E-24 T 23-10-2018 IPR010036 Magnesium-dependent phosphatase-1, eukaryotic/archaeal-type GO:0016791 A0127_04190 c140135e06b2e4f857f093aebdeb3e49 160 Gene3D G3DSA:3.40.50.1000 1 157 4.8E-27 T 23-10-2018 IPR023214 HAD superfamily A0127_04190 c140135e06b2e4f857f093aebdeb3e49 160 TIGRFAM TIGR01681 HAD-SF-IIIC: HAD phosphatase, family IIIC 3 129 7.4E-15 T 23-10-2018 IPR010033 HAD-superfamily phosphatase, subfamily IIIC A0127_04190 c140135e06b2e4f857f093aebdeb3e49 160 SUPERFAMILY SSF56784 2 125 8.81E-18 T 23-10-2018 IPR036412 HAD-like superfamily A0127_06600 b6cc86d50c438217ffa287655e26a357 352 Gene3D G3DSA:3.90.550.10 1 239 6.3E-67 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A0127_06600 b6cc86d50c438217ffa287655e26a357 352 SUPERFAMILY SSF53448 1 304 6.1E-75 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A0127_06600 b6cc86d50c438217ffa287655e26a357 352 Gene3D G3DSA:2.160.10.10 240 350 4.4E-14 T 23-10-2018 A0127_06600 b6cc86d50c438217ffa287655e26a357 352 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 272 299 1.4E-5 T 23-10-2018 IPR001451 Hexapeptide repeat A0127_06600 b6cc86d50c438217ffa287655e26a357 352 TIGRFAM TIGR01208 rmlA_long: glucose-1-phosphate thymidylyltransferase 2 352 1.0E-163 T 23-10-2018 IPR005908 Glucose-1-phosphate thymidylyltransferase, long form A0127_06600 b6cc86d50c438217ffa287655e26a357 352 Pfam PF00483 Nucleotidyl transferase 2 234 6.2E-50 T 23-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 A0127_06215 300c0f8750227b452a5eb0a5542b5545 400 Pfam PF04104 Eukaryotic and archaeal DNA primase, large subunit 147 365 9.0E-35 T 23-10-2018 IPR007238 DNA primase large subunit, eukaryotic/archaeal GO:0003896|GO:0006269 Reactome: R-HSA-113501|Reactome: R-HSA-174411|Reactome: R-HSA-174430|Reactome: R-HSA-68952|Reactome: R-HSA-68962|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183 A0127_06215 300c0f8750227b452a5eb0a5542b5545 400 SUPERFAMILY SSF140914 2 253 3.27E-16 T 23-10-2018 A0127_06215 300c0f8750227b452a5eb0a5542b5545 400 Hamap MF_00701 DNA primase large subunit PriL [priL]. 1 392 27.731 T 23-10-2018 IPR023642 DNA primase large subunit PriL GO:0003896 A0127_06215 300c0f8750227b452a5eb0a5542b5545 400 Gene3D G3DSA:2.20.20.80 113 175 3.4E-41 T 23-10-2018 A0127_06215 300c0f8750227b452a5eb0a5542b5545 400 Gene3D G3DSA:1.20.930.50 8 230 3.4E-41 T 23-10-2018 A0127_06160 b79e3c8f92239d1f4c39ca0de62ae56d 335 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 243 311 3.0E-20 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A0127_06160 b79e3c8f92239d1f4c39ca0de62ae56d 335 SMART SM00382 45 249 1.1E-10 T 23-10-2018 IPR003593 AAA+ ATPase domain A0127_06160 b79e3c8f92239d1f4c39ca0de62ae56d 335 SUPERFAMILY SSF52540 5 263 4.36E-71 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_06160 b79e3c8f92239d1f4c39ca0de62ae56d 335 Pfam PF00005 ABC transporter 37 191 1.5E-31 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A0127_06160 b79e3c8f92239d1f4c39ca0de62ae56d 335 Gene3D G3DSA:3.40.50.300 3 335 2.3E-96 T 23-10-2018 A0127_06160 b79e3c8f92239d1f4c39ca0de62ae56d 335 ProSitePatterns PS00211 ABC transporters family signature. 164 178 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A0127_06160 b79e3c8f92239d1f4c39ca0de62ae56d 335 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 241 331 9.4E-28 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A0127_07260 d1f67425c927bfbb81bfdaad6225c8b3 506 Pfam PF02355 Protein export membrane protein 328 489 5.0E-19 T 23-10-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial A0127_07260 d1f67425c927bfbb81bfdaad6225c8b3 506 Gene3D G3DSA:3.30.70.3400 35 120 1.4E-8 T 23-10-2018 A0127_07260 d1f67425c927bfbb81bfdaad6225c8b3 506 Hamap MF_01463_A Protein translocase subunit SecD [secD]. 6 505 18.931 T 23-10-2018 IPR024912 Protein translocase subunit SecD, archaeal A0127_07260 d1f67425c927bfbb81bfdaad6225c8b3 506 Gene3D G3DSA:1.20.1640.10 313 498 6.8E-14 T 23-10-2018 A0127_07260 d1f67425c927bfbb81bfdaad6225c8b3 506 SUPERFAMILY SSF82866 305 491 2.49E-27 T 23-10-2018 A0127_05795 031ac2b6d91b8726818c6b79d70030ac 480 Gene3D G3DSA:3.40.50.10260 9 207 6.1E-44 T 23-10-2018 IPR036652 YjeF N-terminal domain superfamily MetaCyc: PWY-6938 A0127_05795 031ac2b6d91b8726818c6b79d70030ac 480 Gene3D G3DSA:3.40.1190.20 209 477 1.4E-74 T 23-10-2018 IPR029056 Ribokinase-like A0127_05795 031ac2b6d91b8726818c6b79d70030ac 480 Pfam PF03853 YjeF-related protein N-terminus 22 182 2.2E-34 T 23-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 A0127_05795 031ac2b6d91b8726818c6b79d70030ac 480 ProSitePatterns PS01050 YjeF C-terminal domain signature 2. 415 425 - T 23-10-2018 IPR017953 Carbohydrate kinase, predicted, conserved site A0127_05795 031ac2b6d91b8726818c6b79d70030ac 480 Hamap MF_01966 NAD(P)H-hydrate epimerase [nnrE]. 1 198 18.751 T 23-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 A0127_05795 031ac2b6d91b8726818c6b79d70030ac 480 TIGRFAM TIGR00197 yjeF_nterm: YjeF family N-terminal domain 8 183 1.2E-43 T 23-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 A0127_05795 031ac2b6d91b8726818c6b79d70030ac 480 SUPERFAMILY SSF64153 4 225 2.75E-50 T 23-10-2018 IPR036652 YjeF N-terminal domain superfamily MetaCyc: PWY-6938 A0127_05795 031ac2b6d91b8726818c6b79d70030ac 480 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 204 479 21.732 T 23-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 A0127_05795 031ac2b6d91b8726818c6b79d70030ac 480 PIRSF PIRSF017184 1 479 1.9E-98 T 23-10-2018 IPR030677 Bifunctional NAD(P)H-hydrate repair enzyme Nnr GO:0052855 MetaCyc: PWY-6938 A0127_05795 031ac2b6d91b8726818c6b79d70030ac 480 Pfam PF01256 Carbohydrate kinase 227 467 5.0E-50 T 23-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 A0127_05795 031ac2b6d91b8726818c6b79d70030ac 480 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 211 475 4.8E-70 T 23-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 A0127_05795 031ac2b6d91b8726818c6b79d70030ac 480 SUPERFAMILY SSF53613 212 474 1.12E-60 T 23-10-2018 IPR029056 Ribokinase-like A0127_05545 230f3dd3def1afdb137c874a40830dfa 383 Pfam PF17125 N-terminal domain of 16S rRNA methyltransferase RsmF 8 86 4.1E-7 T 23-10-2018 IPR031341 Ribosomal RNA small subunit methyltransferase F, N-terminal Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 A0127_05545 230f3dd3def1afdb137c874a40830dfa 383 TIGRFAM TIGR00446 nop2p: NOL1/NOP2/sun family putative RNA methylase 168 382 9.8E-65 T 23-10-2018 IPR011023 Nop2p GO:0003723|GO:0006364|GO:0008757 Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 A0127_05545 230f3dd3def1afdb137c874a40830dfa 383 Gene3D G3DSA:3.40.50.150 189 383 1.6E-62 T 23-10-2018 A0127_05545 230f3dd3def1afdb137c874a40830dfa 383 Gene3D G3DSA:3.30.70.3130 2 80 2.1E-12 T 23-10-2018 A0127_05545 230f3dd3def1afdb137c874a40830dfa 383 SMART SM00359 90 164 1.3E-22 T 23-10-2018 IPR002478 PUA domain GO:0003723 A0127_05545 230f3dd3def1afdb137c874a40830dfa 383 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 269 281 2.6E-26 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A0127_05545 230f3dd3def1afdb137c874a40830dfa 383 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 316 332 2.6E-26 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A0127_05545 230f3dd3def1afdb137c874a40830dfa 383 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 203 213 2.6E-26 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A0127_05545 230f3dd3def1afdb137c874a40830dfa 383 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 174 188 2.6E-26 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A0127_05545 230f3dd3def1afdb137c874a40830dfa 383 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 365 382 2.6E-26 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A0127_05545 230f3dd3def1afdb137c874a40830dfa 383 TIGRFAM TIGR00451 unchar_dom_2: uncharacterized domain 2 91 159 2.3E-7 T 23-10-2018 IPR004521 Uncharacterised domain CHP00451 GO:0003723 A0127_05545 230f3dd3def1afdb137c874a40830dfa 383 SUPERFAMILY SSF53335 7 383 3.34E-57 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A0127_05545 230f3dd3def1afdb137c874a40830dfa 383 Pfam PF01189 16S rRNA methyltransferase RsmB/F 193 381 1.9E-58 T 23-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 A0127_05545 230f3dd3def1afdb137c874a40830dfa 383 SUPERFAMILY SSF88697 89 160 3.2E-18 T 23-10-2018 IPR015947 PUA-like superfamily A0127_05545 230f3dd3def1afdb137c874a40830dfa 383 Gene3D G3DSA:2.30.130.70 81 163 2.2E-18 T 23-10-2018 A0127_05545 230f3dd3def1afdb137c874a40830dfa 383 Pfam PF01472 PUA domain 90 159 8.1E-18 T 23-10-2018 IPR002478 PUA domain GO:0003723 A0127_07285 4220d23482938a4c787e25178c8d81e8 169 Gene3D G3DSA:3.10.450.220 2 95 6.8E-46 T 23-10-2018 A0127_07285 4220d23482938a4c787e25178c8d81e8 169 Pfam PF03657 Uncharacterised protein family (UPF0113) 7 167 2.7E-13 T 23-10-2018 IPR005155 Ribosome biogenesis factor NIP7-like Reactome: R-HSA-6791226 A0127_07285 4220d23482938a4c787e25178c8d81e8 169 Gene3D G3DSA:2.30.130.10 96 167 4.8E-20 T 23-10-2018 IPR036974 PUA domain superfamily GO:0003723 A0127_06320 6880afcf9ed22ebee7c23300bb23d108 271 Gene3D G3DSA:3.60.15.10 1 253 2.2E-30 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A0127_06320 6880afcf9ed22ebee7c23300bb23d108 271 Pfam PF12706 Beta-lactamase superfamily domain 32 220 2.3E-28 T 23-10-2018 IPR001279 Metallo-beta-lactamase A0127_06320 6880afcf9ed22ebee7c23300bb23d108 271 SUPERFAMILY SSF56281 3 254 3.25E-38 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A0127_03490 5cf8d02945424906aca706e8dee9caf7 327 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 234 303 2.6E-20 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A0127_03490 5cf8d02945424906aca706e8dee9caf7 327 SMART SM00382 41 232 2.8E-15 T 23-10-2018 IPR003593 AAA+ ATPase domain A0127_03490 5cf8d02945424906aca706e8dee9caf7 327 Pfam PF00005 ABC transporter 33 183 4.6E-32 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A0127_03490 5cf8d02945424906aca706e8dee9caf7 327 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A0127_03490 5cf8d02945424906aca706e8dee9caf7 327 SUPERFAMILY SSF52540 7 253 1.33E-75 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_03490 5cf8d02945424906aca706e8dee9caf7 327 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 232 323 1.9E-29 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A0127_03490 5cf8d02945424906aca706e8dee9caf7 327 Gene3D G3DSA:3.40.50.300 5 327 1.3E-103 T 23-10-2018 A0127_05285 659cecc8cf5e703bf6242737f005241c 292 Pfam PF00175 Oxidoreductase NAD-binding domain 125 229 3.5E-13 T 23-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 A0127_05285 659cecc8cf5e703bf6242737f005241c 292 PRINTS PR00410 Phenol hydroxylase reductase family signature 50 62 1.3E-7 T 23-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 A0127_05285 659cecc8cf5e703bf6242737f005241c 292 PRINTS PR00410 Phenol hydroxylase reductase family signature 124 143 1.3E-7 T 23-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 A0127_05285 659cecc8cf5e703bf6242737f005241c 292 PRINTS PR00410 Phenol hydroxylase reductase family signature 216 224 1.3E-7 T 23-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 A0127_05285 659cecc8cf5e703bf6242737f005241c 292 Gene3D G3DSA:2.40.30.10 14 112 2.8E-20 T 23-10-2018 A0127_05285 659cecc8cf5e703bf6242737f005241c 292 Gene3D G3DSA:2.10.240.10 248 284 2.2E-7 T 23-10-2018 IPR037117 Dihydroorotate dehydrogenase, electron transfer subunit, Fe-S binding domain superfamily A0127_05285 659cecc8cf5e703bf6242737f005241c 292 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 248 283 2.2E-12 T 23-10-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain A0127_05285 659cecc8cf5e703bf6242737f005241c 292 Gene3D G3DSA:3.40.50.80 119 246 1.2E-21 T 23-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A0127_05285 659cecc8cf5e703bf6242737f005241c 292 SUPERFAMILY SSF63380 11 116 1.33E-24 T 23-10-2018 IPR017938 Riboflavin synthase-like beta-barrel A0127_05285 659cecc8cf5e703bf6242737f005241c 292 SUPERFAMILY SSF52343 108 283 2.23E-31 T 23-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A0127_05285 659cecc8cf5e703bf6242737f005241c 292 Pfam PF00970 Oxidoreductase FAD-binding domain 27 111 2.6E-8 T 23-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 A0127_05285 659cecc8cf5e703bf6242737f005241c 292 PIRSF PIRSF006816 14 291 1.4E-83 T 23-10-2018 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 A0127_03030 8b066e80c4ce188b367adff4157de579 307 Gene3D G3DSA:3.30.300.10 190 307 3.0E-53 T 23-10-2018 A0127_03030 8b066e80c4ce188b367adff4157de579 307 Gene3D G3DSA:3.40.50.620 2 189 1.6E-76 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A0127_03030 8b066e80c4ce188b367adff4157de579 307 Hamap MF_00345 GMP synthase [glutamine-hydrolyzing] subunit B [guaAB]. 1 307 45.528 T 23-10-2018 IPR026598 GMP synthase subunit B KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 A0127_03030 8b066e80c4ce188b367adff4157de579 307 Pfam PF00958 GMP synthase C terminal domain 217 306 2.8E-34 T 23-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 A0127_03030 8b066e80c4ce188b367adff4157de579 307 SUPERFAMILY SSF54810 189 307 5.23E-45 T 23-10-2018 A0127_03030 8b066e80c4ce188b367adff4157de579 307 SUPERFAMILY SSF52402 2 224 1.06E-53 T 23-10-2018 A0127_03030 8b066e80c4ce188b367adff4157de579 307 Pfam PF02540 NAD synthase 4 81 1.1E-5 T 23-10-2018 IPR022310 NAD/GMP synthase A0127_03030 8b066e80c4ce188b367adff4157de579 307 Pfam PF02540 NAD synthase 157 186 7.3E-5 T 23-10-2018 IPR022310 NAD/GMP synthase A0127_03030 8b066e80c4ce188b367adff4157de579 307 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 4 307 7.7E-150 T 23-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 A0127_09990 beed20fa7f2d5c08b5c549d66b6b9bb4 171 Pfam PF01923 Cobalamin adenosyltransferase 3 159 1.8E-49 T 23-10-2018 IPR016030 Cobalamin adenosyltransferase-like KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 A0127_09990 beed20fa7f2d5c08b5c549d66b6b9bb4 171 Gene3D G3DSA:1.20.1200.10 25 171 7.3E-49 T 23-10-2018 IPR036451 Cobalamin adenosyltransferase-like superfamily KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 A0127_09990 beed20fa7f2d5c08b5c549d66b6b9bb4 171 TIGRFAM TIGR00636 PduO_Nterm: ATP:cob(I)alamin adenosyltransferase 4 169 4.2E-59 T 23-10-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 A0127_09990 beed20fa7f2d5c08b5c549d66b6b9bb4 171 ProDom PD007457 TRANSFERASE ADENOSYLTRANSFERASE COBALAMIN ATP:COBIALAMIN ADENOSYLTRANSFERASE PDUO TYPE RELATED ACIDURIA YVQK 20 165 6.0E-64 T 23-10-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 A0127_09990 beed20fa7f2d5c08b5c549d66b6b9bb4 171 SUPERFAMILY SSF89028 2 165 4.71E-51 T 23-10-2018 IPR036451 Cobalamin adenosyltransferase-like superfamily KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 A0127_03450 d48d1eae8458214a46707e7eb1048ce8 253 Pfam PF08704 tRNA methyltransferase complex GCD14 subunit 74 233 2.6E-25 T 23-10-2018 IPR014816 tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 GO:0016429|GO:0030488|GO:0031515 MetaCyc: PWY-6829 A0127_03450 d48d1eae8458214a46707e7eb1048ce8 253 Gene3D G3DSA:3.40.50.150 63 253 5.9E-67 T 23-10-2018 A0127_03450 d48d1eae8458214a46707e7eb1048ce8 253 PIRSF PIRSF017269 1 253 2.7E-79 T 23-10-2018 IPR014816 tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 GO:0016429|GO:0030488|GO:0031515 MetaCyc: PWY-6829 A0127_03450 d48d1eae8458214a46707e7eb1048ce8 253 Pfam PF14801 tRNA methyltransferase complex GCD14 subunit N-term 3 46 1.2E-8 T 23-10-2018 A0127_03450 d48d1eae8458214a46707e7eb1048ce8 253 Gene3D G3DSA:3.10.330.20 1 61 2.0E-24 T 23-10-2018 A0127_03450 d48d1eae8458214a46707e7eb1048ce8 253 SUPERFAMILY SSF53335 1 252 1.13E-76 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A0127_07825 3d87f4fbd8458f581d167a303da05208 336 Gene3D G3DSA:3.30.230.10 1 185 3.1E-50 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A0127_07825 3d87f4fbd8458f581d167a303da05208 336 TIGRFAM TIGR00549 mevalon_kin: mevalonate kinase 10 301 4.5E-85 T 23-10-2018 IPR006205 Mevalonate kinase GO:0004496|GO:0005524|GO:0005737|GO:0008299 KEGG: 00900+2.7.1.36|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-2426168 A0127_07825 3d87f4fbd8458f581d167a303da05208 336 Hamap MF_00217 Mevalonate kinase [mvk]. 6 330 58.251 T 23-10-2018 IPR022937 Mevalonate kinase, archaeal GO:0004496 KEGG: 00900+2.7.1.36|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-922 A0127_07825 3d87f4fbd8458f581d167a303da05208 336 Gene3D G3DSA:3.30.70.890 190 322 7.0E-41 T 23-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily A0127_07825 3d87f4fbd8458f581d167a303da05208 336 Pfam PF08544 GHMP kinases C terminal 248 314 8.4E-13 T 23-10-2018 IPR013750 GHMP kinase, C-terminal domain A0127_07825 3d87f4fbd8458f581d167a303da05208 336 PRINTS PR00959 Mevalonate kinase family signature 153 172 7.2E-29 T 23-10-2018 A0127_07825 3d87f4fbd8458f581d167a303da05208 336 PRINTS PR00959 Mevalonate kinase family signature 286 303 7.2E-29 T 23-10-2018 A0127_07825 3d87f4fbd8458f581d167a303da05208 336 PRINTS PR00959 Mevalonate kinase family signature 10 34 7.2E-29 T 23-10-2018 A0127_07825 3d87f4fbd8458f581d167a303da05208 336 PRINTS PR00959 Mevalonate kinase family signature 110 132 7.2E-29 T 23-10-2018 A0127_07825 3d87f4fbd8458f581d167a303da05208 336 SUPERFAMILY SSF55060 186 332 8.82E-37 T 23-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily A0127_07825 3d87f4fbd8458f581d167a303da05208 336 Pfam PF00288 GHMP kinases N terminal domain 106 172 4.3E-16 T 23-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 A0127_07825 3d87f4fbd8458f581d167a303da05208 336 SUPERFAMILY SSF54211 1 183 6.45E-46 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A0127_07825 3d87f4fbd8458f581d167a303da05208 336 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 112 123 - T 23-10-2018 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 A0127_08230 06fb3808daa7256853b594019a1ba19e 502 SUPERFAMILY SSF53383 12 488 9.68E-122 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A0127_08230 06fb3808daa7256853b594019a1ba19e 502 Pfam PF02347 Glycine cleavage system P-protein 33 307 3.6E-10 T 23-10-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 A0127_08230 06fb3808daa7256853b594019a1ba19e 502 Gene3D G3DSA:3.40.640.10 86 316 2.1E-60 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A0127_08230 06fb3808daa7256853b594019a1ba19e 502 Hamap MF_00713 Probable glycine dehydrogenase (decarboxylating) subunit 2 [gcvPB]. 10 490 61.15 T 23-10-2018 IPR023012 Probable glycine dehydrogenase (decarboxylating) subunit 2 GO:0004375|GO:0019464 KEGG: 00260+1.4.4.2 A0127_08230 06fb3808daa7256853b594019a1ba19e 502 Gene3D G3DSA:3.90.1150.10 340 475 5.6E-43 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A0127_10240 caa1fe607d624d2fdae522fdc3759242 693 PRINTS PR00941 Cadmium-transporting ATPase signature 260 276 1.1E-10 T 23-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 A0127_10240 caa1fe607d624d2fdae522fdc3759242 693 PRINTS PR00941 Cadmium-transporting ATPase signature 5 14 1.1E-10 T 23-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 A0127_10240 caa1fe607d624d2fdae522fdc3759242 693 PRINTS PR00941 Cadmium-transporting ATPase signature 279 293 1.1E-10 T 23-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 A0127_10240 caa1fe607d624d2fdae522fdc3759242 693 PRINTS PR00941 Cadmium-transporting ATPase signature 107 124 1.1E-10 T 23-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 A0127_10240 caa1fe607d624d2fdae522fdc3759242 693 PRINTS PR00941 Cadmium-transporting ATPase signature 179 199 1.1E-10 T 23-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 A0127_10240 caa1fe607d624d2fdae522fdc3759242 693 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 397 403 - T 23-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 A0127_10240 caa1fe607d624d2fdae522fdc3759242 693 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 168 666 8.8E-82 T 23-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A0127_10240 caa1fe607d624d2fdae522fdc3759242 693 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 145 690 2.8E-178 T 23-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 A0127_10240 caa1fe607d624d2fdae522fdc3759242 693 ProSitePatterns PS01047 Heavy-metal-associated domain. 7 35 - T 23-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 A0127_10240 caa1fe607d624d2fdae522fdc3759242 693 Gene3D G3DSA:3.40.1110.10 406 517 1.5E-83 T 23-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 A0127_10240 caa1fe607d624d2fdae522fdc3759242 693 Pfam PF00702 haloacid dehalogenase-like hydrolase 393 602 2.2E-39 T 23-10-2018 A0127_10240 caa1fe607d624d2fdae522fdc3759242 693 SUPERFAMILY SSF81665 145 688 9.81E-15 T 23-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 A0127_10240 caa1fe607d624d2fdae522fdc3759242 693 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 145 693 1.3E-165 T 23-10-2018 A0127_10240 caa1fe607d624d2fdae522fdc3759242 693 Gene3D G3DSA:3.40.50.1000 376 641 1.5E-83 T 23-10-2018 IPR023214 HAD superfamily A0127_10240 caa1fe607d624d2fdae522fdc3759242 693 SUPERFAMILY SSF81653 199 294 2.35E-26 T 23-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 A0127_10240 caa1fe607d624d2fdae522fdc3759242 693 Pfam PF00122 E1-E2 ATPase 195 375 1.2E-55 T 23-10-2018 A0127_10240 caa1fe607d624d2fdae522fdc3759242 693 SUPERFAMILY SSF55008 4 58 1.7E-9 T 23-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 A0127_10240 caa1fe607d624d2fdae522fdc3759242 693 SUPERFAMILY SSF56784 393 689 7.76E-62 T 23-10-2018 IPR036412 HAD-like superfamily A0127_10240 caa1fe607d624d2fdae522fdc3759242 693 Pfam PF00403 Heavy-metal-associated domain 6 57 1.2E-10 T 23-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 A0127_10240 caa1fe607d624d2fdae522fdc3759242 693 Gene3D G3DSA:2.70.150.20 187 299 1.0E-34 T 23-10-2018 A0127_10240 caa1fe607d624d2fdae522fdc3759242 693 Gene3D G3DSA:3.30.70.100 3 81 4.7E-10 T 23-10-2018 A0127_10240 caa1fe607d624d2fdae522fdc3759242 693 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 533 543 2.2E-22 T 23-10-2018 A0127_10240 caa1fe607d624d2fdae522fdc3759242 693 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 395 409 2.2E-22 T 23-10-2018 A0127_10240 caa1fe607d624d2fdae522fdc3759242 693 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 244 258 2.2E-22 T 23-10-2018 A0127_10240 caa1fe607d624d2fdae522fdc3759242 693 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 588 607 2.2E-22 T 23-10-2018 A0127_10240 caa1fe607d624d2fdae522fdc3759242 693 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 612 624 2.2E-22 T 23-10-2018 A0127_04860 37cf21cb4ead6f97d21a77baa291c67a 141 SUPERFAMILY SSF54909 62 141 2.82E-17 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel A0127_04860 37cf21cb4ead6f97d21a77baa291c67a 141 Gene3D G3DSA:3.30.70.920 65 141 1.7E-20 T 23-10-2018 A0127_04860 37cf21cb4ead6f97d21a77baa291c67a 141 SUPERFAMILY SSF46785 1 62 1.28E-18 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A0127_04860 37cf21cb4ead6f97d21a77baa291c67a 141 Pfam PF01037 Lrp/AsnC ligand binding domain 70 138 1.8E-15 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A0127_04860 37cf21cb4ead6f97d21a77baa291c67a 141 SMART SM00344 2 108 1.5E-49 T 23-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A0127_04860 37cf21cb4ead6f97d21a77baa291c67a 141 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 18 29 4.3E-16 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A0127_04860 37cf21cb4ead6f97d21a77baa291c67a 141 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 29 48 4.3E-16 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A0127_04860 37cf21cb4ead6f97d21a77baa291c67a 141 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 2 18 4.3E-16 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A0127_04860 37cf21cb4ead6f97d21a77baa291c67a 141 Pfam PF13412 Winged helix-turn-helix DNA-binding 2 49 5.8E-15 T 23-10-2018 A0127_04860 37cf21cb4ead6f97d21a77baa291c67a 141 Gene3D G3DSA:1.10.10.10 1 52 1.2E-21 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A0127_04860 37cf21cb4ead6f97d21a77baa291c67a 141 ProSitePatterns PS00519 AsnC-type HTH domain signature. 20 46 - T 23-10-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site A0127_03335 42302bfea24fff89782b3c441a0a42b1 279 SUPERFAMILY SSF52096 65 240 7.79E-29 T 23-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A0127_03335 42302bfea24fff89782b3c441a0a42b1 279 Gene3D G3DSA:3.90.226.10 34 267 7.0E-24 T 23-10-2018 A0127_03335 42302bfea24fff89782b3c441a0a42b1 279 Pfam PF01972 Serine dehydrogenase proteinase 2 277 3.1E-155 T 23-10-2018 IPR002825 Peptidase S49, serine-peptidase prokaryotes GO:0016021 A0127_01725 7dfa15a0d50a63eff03413cfe23253fe 150 Gene3D G3DSA:3.40.50.1000 7 144 6.9E-10 T 23-10-2018 IPR023214 HAD superfamily A0127_01725 7dfa15a0d50a63eff03413cfe23253fe 150 SUPERFAMILY SSF56784 12 132 2.72E-12 T 23-10-2018 IPR036412 HAD-like superfamily A0127_01600 e18cc27b76421636d25bce51c10e08fc 111 SUPERFAMILY SSF50346 4 79 4.45E-13 T 23-10-2018 IPR011033 PRC-barrel-like superfamily A0127_01600 e18cc27b76421636d25bce51c10e08fc 111 Pfam PF05239 PRC-barrel domain 3 82 1.9E-13 T 23-10-2018 IPR027275 PRC-barrel domain A0127_01600 e18cc27b76421636d25bce51c10e08fc 111 Gene3D G3DSA:2.30.30.240 4 81 1.1E-5 T 23-10-2018 A0127_08885 f40ed694cadb8ca71d58490a4025c4a3 194 Gene3D G3DSA:3.40.30.10 30 135 1.8E-8 T 23-10-2018 A0127_08885 f40ed694cadb8ca71d58490a4025c4a3 194 SUPERFAMILY SSF52833 49 126 1.71E-11 T 23-10-2018 IPR036249 Thioredoxin-like superfamily A0127_01295 e880940d517b030796bdd7717b44728b 388 TIGRFAM TIGR01254 sfuA: ABC transporter periplasmic binding protein, thiB subfamily 26 333 1.1E-81 T 23-10-2018 IPR005948 Thiamine/thiamin pyrophosphate-binding periplasmic protein, ABC transporter GO:0015888|GO:0030975 A0127_01295 e880940d517b030796bdd7717b44728b 388 PIRSF PIRSF002825 2 338 4.4E-53 T 23-10-2018 IPR026045 Ferric binding protein A0127_01295 e880940d517b030796bdd7717b44728b 388 TIGRFAM TIGR04288 CGP_CTERM: CGP-CTERM domain 368 387 4.7E-8 T 23-10-2018 IPR027552 CGP-CTERM domain A0127_01295 e880940d517b030796bdd7717b44728b 388 SUPERFAMILY SSF53850 26 334 2.86E-75 T 23-10-2018 A0127_01295 e880940d517b030796bdd7717b44728b 388 Gene3D G3DSA:3.40.190.10 132 334 3.1E-105 T 23-10-2018 A0127_01295 e880940d517b030796bdd7717b44728b 388 Gene3D G3DSA:3.40.190.10 31 307 3.1E-105 T 23-10-2018 A0127_01295 e880940d517b030796bdd7717b44728b 388 Pfam PF13416 Bacterial extracellular solute-binding protein 46 301 1.2E-26 T 23-10-2018 IPR006059 Bacterial extracellular solute-binding protein A0127_09245 95766d9c678c13e374f2b3bf68b82dd4 257 Hamap MF_00060 5'/3'-nucleotidase SurE [surE]. 1 257 32.263 T 23-10-2018 IPR030048 Survival protein SurE GO:0008252 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 A0127_09245 95766d9c678c13e374f2b3bf68b82dd4 257 TIGRFAM TIGR00087 surE: 5'/3'-nucleotidase SurE 1 243 1.3E-67 T 23-10-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 A0127_09245 95766d9c678c13e374f2b3bf68b82dd4 257 SUPERFAMILY SSF64167 1 255 1.2E-71 T 23-10-2018 A0127_09245 95766d9c678c13e374f2b3bf68b82dd4 257 Gene3D G3DSA:3.40.1210.10 1 257 3.1E-81 T 23-10-2018 IPR036523 SurE-like phosphatase/nucleotidase superfamily GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 A0127_09245 95766d9c678c13e374f2b3bf68b82dd4 257 Pfam PF01975 Survival protein SurE 3 192 6.0E-52 T 23-10-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 A0127_10090 792f5929a7fa0c33f76d55bc8493cba7 799 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 223 794 2.0E-197 T 23-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 A0127_10090 792f5929a7fa0c33f76d55bc8493cba7 799 Gene3D G3DSA:2.70.150.20 279 391 3.9E-45 T 23-10-2018 A0127_10090 792f5929a7fa0c33f76d55bc8493cba7 799 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 204 795 1.8E-183 T 23-10-2018 A0127_10090 792f5929a7fa0c33f76d55bc8493cba7 799 Pfam PF00122 E1-E2 ATPase 287 465 6.8E-60 T 23-10-2018 A0127_10090 792f5929a7fa0c33f76d55bc8493cba7 799 Gene3D G3DSA:3.40.1110.10 498 617 9.8E-100 T 23-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 A0127_10090 792f5929a7fa0c33f76d55bc8493cba7 799 SUPERFAMILY SSF55008 1 67 1.44E-20 T 23-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 A0127_10090 792f5929a7fa0c33f76d55bc8493cba7 799 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 489 495 - T 23-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 A0127_10090 792f5929a7fa0c33f76d55bc8493cba7 799 SUPERFAMILY SSF81653 290 386 1.44E-31 T 23-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 A0127_10090 792f5929a7fa0c33f76d55bc8493cba7 799 Pfam PF00403 Heavy-metal-associated domain 5 65 2.2E-15 T 23-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 A0127_10090 792f5929a7fa0c33f76d55bc8493cba7 799 Pfam PF00403 Heavy-metal-associated domain 74 135 6.5E-16 T 23-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 A0127_10090 792f5929a7fa0c33f76d55bc8493cba7 799 Pfam PF00702 haloacid dehalogenase-like hydrolase 485 699 5.1E-46 T 23-10-2018 A0127_10090 792f5929a7fa0c33f76d55bc8493cba7 799 SUPERFAMILY SSF81665 251 479 2.75E-13 T 23-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 A0127_10090 792f5929a7fa0c33f76d55bc8493cba7 799 SUPERFAMILY SSF56784 485 792 1.03E-63 T 23-10-2018 IPR036412 HAD-like superfamily A0127_10090 792f5929a7fa0c33f76d55bc8493cba7 799 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 259 765 3.1E-106 T 23-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A0127_10090 792f5929a7fa0c33f76d55bc8493cba7 799 Gene3D G3DSA:3.30.70.100 70 157 4.7E-23 T 23-10-2018 A0127_10090 792f5929a7fa0c33f76d55bc8493cba7 799 Gene3D G3DSA:3.30.70.100 1 69 2.3E-22 T 23-10-2018 A0127_10090 792f5929a7fa0c33f76d55bc8493cba7 799 TIGRFAM TIGR00003 TIGR00003: copper ion binding protein 4 66 3.3E-16 T 23-10-2018 IPR006122 Heavy metal-associated domain, copper ion-binding GO:0005507 Reactome: R-HSA-936837 A0127_10090 792f5929a7fa0c33f76d55bc8493cba7 799 TIGRFAM TIGR00003 TIGR00003: copper ion binding protein 76 135 7.8E-14 T 23-10-2018 IPR006122 Heavy metal-associated domain, copper ion-binding GO:0005507 Reactome: R-HSA-936837 A0127_10090 792f5929a7fa0c33f76d55bc8493cba7 799 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 487 501 4.1E-27 T 23-10-2018 A0127_10090 792f5929a7fa0c33f76d55bc8493cba7 799 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 610 621 4.1E-27 T 23-10-2018 A0127_10090 792f5929a7fa0c33f76d55bc8493cba7 799 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 336 350 4.1E-27 T 23-10-2018 A0127_10090 792f5929a7fa0c33f76d55bc8493cba7 799 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 685 704 4.1E-27 T 23-10-2018 A0127_10090 792f5929a7fa0c33f76d55bc8493cba7 799 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 708 720 4.1E-27 T 23-10-2018 A0127_10090 792f5929a7fa0c33f76d55bc8493cba7 799 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 632 642 4.1E-27 T 23-10-2018 A0127_10090 792f5929a7fa0c33f76d55bc8493cba7 799 Gene3D G3DSA:3.40.50.1000 468 737 9.8E-100 T 23-10-2018 IPR023214 HAD superfamily A0127_10090 792f5929a7fa0c33f76d55bc8493cba7 799 SUPERFAMILY SSF55008 72 139 6.68E-21 T 23-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 A0127_10090 792f5929a7fa0c33f76d55bc8493cba7 799 PRINTS PR00943 Copper-transporting ATPase signature 409 423 1.1E-13 T 23-10-2018 A0127_10090 792f5929a7fa0c33f76d55bc8493cba7 799 PRINTS PR00943 Copper-transporting ATPase signature 116 136 1.1E-13 T 23-10-2018 A0127_10090 792f5929a7fa0c33f76d55bc8493cba7 799 PRINTS PR00943 Copper-transporting ATPase signature 256 275 1.1E-13 T 23-10-2018 A0127_10090 792f5929a7fa0c33f76d55bc8493cba7 799 PRINTS PR00943 Copper-transporting ATPase signature 662 679 1.1E-13 T 23-10-2018 A0127_10090 792f5929a7fa0c33f76d55bc8493cba7 799 PRINTS PR00943 Copper-transporting ATPase signature 719 733 1.1E-13 T 23-10-2018 A0127_10090 792f5929a7fa0c33f76d55bc8493cba7 799 PRINTS PR00943 Copper-transporting ATPase signature 276 294 1.1E-13 T 23-10-2018 A0127_10090 792f5929a7fa0c33f76d55bc8493cba7 799 PRINTS PR00943 Copper-transporting ATPase signature 470 485 1.1E-13 T 23-10-2018 A0127_08970 bc2f1760bc503b08e4d78dbfa5c87c5b 533 Gene3D G3DSA:3.40.50.300 1 283 5.7E-138 T 23-10-2018 A0127_08970 bc2f1760bc503b08e4d78dbfa5c87c5b 533 Pfam PF06418 CTP synthase N-terminus 3 265 5.5E-126 T 23-10-2018 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 A0127_08970 bc2f1760bc503b08e4d78dbfa5c87c5b 533 Hamap MF_01227 CTP synthase [pyrG]. 2 530 52.969 T 23-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 A0127_08970 bc2f1760bc503b08e4d78dbfa5c87c5b 533 SUPERFAMILY SSF52317 288 528 2.45E-79 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A0127_08970 bc2f1760bc503b08e4d78dbfa5c87c5b 533 SUPERFAMILY SSF52540 2 265 3.54E-120 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_08970 bc2f1760bc503b08e4d78dbfa5c87c5b 533 TIGRFAM TIGR00337 PyrG: CTP synthase 1 525 8.2E-253 T 23-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 A0127_08970 bc2f1760bc503b08e4d78dbfa5c87c5b 533 Pfam PF00117 Glutamine amidotransferase class-I 300 524 2.4E-57 T 23-10-2018 IPR017926 Glutamine amidotransferase A0127_08970 bc2f1760bc503b08e4d78dbfa5c87c5b 533 Gene3D G3DSA:3.40.50.880 284 533 1.5E-107 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A0127_04930 7fb1b041f96f9b4943fd0ee5ab26c784 343 Pfam PF13429 Tetratricopeptide repeat 165 312 1.3E-8 T 23-10-2018 A0127_04930 7fb1b041f96f9b4943fd0ee5ab26c784 343 Gene3D G3DSA:1.25.40.10 110 337 3.3E-17 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A0127_04930 7fb1b041f96f9b4943fd0ee5ab26c784 343 SUPERFAMILY SSF48452 130 323 7.27E-22 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A0127_09810 ebedf8684265284e7568f0fd382ea439 1123 Pfam PF04565 RNA polymerase Rpb2, domain 3 425 489 1.7E-30 T 23-10-2018 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A0127_09810 ebedf8684265284e7568f0fd382ea439 1123 Pfam PF00562 RNA polymerase Rpb2, domain 6 654 1026 1.8E-132 T 23-10-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A0127_09810 ebedf8684265284e7568f0fd382ea439 1123 TIGRFAM TIGR03670 rpoB_arch: DNA-directed RNA polymerase subunit B 522 1122 0.0 T 23-10-2018 IPR019969 DNA-directed RNA polymerase subunit B (Rpo2) GO:0003677|GO:0003899|GO:0006351|GO:0008270 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A0127_09810 ebedf8684265284e7568f0fd382ea439 1123 Gene3D G3DSA:2.40.270.10 654 1008 1.0E-146 T 23-10-2018 IPR037033 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A0127_09810 ebedf8684265284e7568f0fd382ea439 1123 Pfam PF04560 RNA polymerase Rpb2, domain 7 1028 1118 3.9E-31 T 23-10-2018 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A0127_09810 ebedf8684265284e7568f0fd382ea439 1123 ProSitePatterns PS01166 RNA polymerases beta chain signature. 879 891 - T 23-10-2018 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A0127_09810 ebedf8684265284e7568f0fd382ea439 1123 Gene3D G3DSA:2.40.50.150 684 875 1.0E-146 T 23-10-2018 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A0127_09810 ebedf8684265284e7568f0fd382ea439 1123 Pfam PF04566 RNA polymerase Rpb2, domain 4 522 585 1.3E-19 T 23-10-2018 IPR007646 RNA polymerase Rpb2, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A0127_09810 ebedf8684265284e7568f0fd382ea439 1123 Gene3D G3DSA:3.90.1100.10 22 180 2.7E-12 T 23-10-2018 A0127_09810 ebedf8684265284e7568f0fd382ea439 1123 Gene3D G3DSA:3.90.1100.10 338 514 5.1E-56 T 23-10-2018 A0127_09810 ebedf8684265284e7568f0fd382ea439 1123 SUPERFAMILY SSF64484 10 1121 0.0 T 23-10-2018 A0127_09810 ebedf8684265284e7568f0fd382ea439 1123 Gene3D G3DSA:3.90.1110.10 181 337 7.7E-61 T 23-10-2018 IPR037034 RNA polymerase Rpb2, domain 2 superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A0127_09810 ebedf8684265284e7568f0fd382ea439 1123 Pfam PF04561 RNA polymerase Rpb2, domain 2 176 349 8.9E-41 T 23-10-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A0127_09810 ebedf8684265284e7568f0fd382ea439 1123 Gene3D G3DSA:3.90.1800.10 1013 1121 2.9E-41 T 23-10-2018 A0127_09810 ebedf8684265284e7568f0fd382ea439 1123 Pfam PF04567 RNA polymerase Rpb2, domain 5 606 638 3.9E-9 T 23-10-2018 IPR007647 RNA polymerase Rpb2, domain 5 GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A0127_09810 ebedf8684265284e7568f0fd382ea439 1123 Pfam PF04563 RNA polymerase beta subunit 30 382 1.1E-53 T 23-10-2018 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A0127_01905 5640bee27de956a828470b6aed4738dd 454 Gene3D G3DSA:1.10.275.10 1 100 2.8E-37 T 23-10-2018 IPR024083 Fumarase/histidase, N-terminal A0127_01905 5640bee27de956a828470b6aed4738dd 454 PRINTS PR00145 Argininosuccinate lyase family signature 136 156 1.9E-11 T 23-10-2018 A0127_01905 5640bee27de956a828470b6aed4738dd 454 PRINTS PR00145 Argininosuccinate lyase family signature 227 251 1.9E-11 T 23-10-2018 A0127_01905 5640bee27de956a828470b6aed4738dd 454 PRINTS PR00145 Argininosuccinate lyase family signature 272 288 1.9E-11 T 23-10-2018 A0127_01905 5640bee27de956a828470b6aed4738dd 454 PRINTS PR00145 Argininosuccinate lyase family signature 95 117 1.9E-11 T 23-10-2018 A0127_01905 5640bee27de956a828470b6aed4738dd 454 Gene3D G3DSA:1.20.200.10 101 358 2.2E-94 T 23-10-2018 A0127_01905 5640bee27de956a828470b6aed4738dd 454 Pfam PF00206 Lyase 13 293 3.5E-58 T 23-10-2018 IPR022761 Fumarate lyase, N-terminal A0127_01905 5640bee27de956a828470b6aed4738dd 454 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 6 438 1.5E-185 T 23-10-2018 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A0127_01905 5640bee27de956a828470b6aed4738dd 454 ProSitePatterns PS00163 Fumarate lyases signature. 272 281 - T 23-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 A0127_01905 5640bee27de956a828470b6aed4738dd 454 PRINTS PR00149 Fumarate lyase superfamily signature 272 288 2.6E-27 T 23-10-2018 IPR000362 Fumarate lyase family A0127_01905 5640bee27de956a828470b6aed4738dd 454 PRINTS PR00149 Fumarate lyase superfamily signature 227 254 2.6E-27 T 23-10-2018 IPR000362 Fumarate lyase family A0127_01905 5640bee27de956a828470b6aed4738dd 454 PRINTS PR00149 Fumarate lyase superfamily signature 96 114 2.6E-27 T 23-10-2018 IPR000362 Fumarate lyase family A0127_01905 5640bee27de956a828470b6aed4738dd 454 PRINTS PR00149 Fumarate lyase superfamily signature 141 159 2.6E-27 T 23-10-2018 IPR000362 Fumarate lyase family A0127_01905 5640bee27de956a828470b6aed4738dd 454 SUPERFAMILY SSF48557 4 442 3.77E-133 T 23-10-2018 IPR008948 L-Aspartase-like GO:0003824 A0127_01905 5640bee27de956a828470b6aed4738dd 454 Pfam PF10397 Adenylosuccinate lyase C-terminus 362 438 9.2E-20 T 23-10-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A0127_01905 5640bee27de956a828470b6aed4738dd 454 SMART SM00998 360 439 6.2E-33 T 23-10-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A0127_01905 5640bee27de956a828470b6aed4738dd 454 Gene3D G3DSA:1.10.40.30 359 439 6.7E-24 T 23-10-2018 A0127_04275 e723d84a82279c06a66386947cd4925a 395 Pfam PF00155 Aminotransferase class I and II 39 383 6.0E-70 T 23-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A0127_04275 e723d84a82279c06a66386947cd4925a 395 TIGRFAM TIGR01825 gly_Cac_T_rel: putative pyridoxal phosphate-dependent acyltransferase 7 394 7.1E-202 T 23-10-2018 IPR010962 Putative 8-amino-7-oxononanoate synthase, Archaea/Firmicutes type A0127_04275 e723d84a82279c06a66386947cd4925a 395 SUPERFAMILY SSF53383 4 391 3.36E-118 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A0127_04275 e723d84a82279c06a66386947cd4925a 395 Gene3D G3DSA:3.90.1150.10 35 385 3.8E-140 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A0127_04275 e723d84a82279c06a66386947cd4925a 395 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 238 247 - T 23-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 A0127_04275 e723d84a82279c06a66386947cd4925a 395 Gene3D G3DSA:3.40.640.10 55 291 3.8E-140 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A0127_02245 d6dfc54239ddbbbbcaaa3bdf7aac2c1a 310 Gene3D G3DSA:3.40.50.20 1 83 5.1E-30 T 23-10-2018 A0127_02245 d6dfc54239ddbbbbcaaa3bdf7aac2c1a 310 Pfam PF06973 Domain of unknown function (DUF1297) 158 310 2.6E-42 T 23-10-2018 IPR009720 IMP biosynthesis enzyme PurP, C-terminal GO:0000287|GO:0005524|GO:0006188|GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 A0127_02245 d6dfc54239ddbbbbcaaa3bdf7aac2c1a 310 Gene3D G3DSA:3.30.1490.20 112 165 2.4E-78 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 A0127_02245 d6dfc54239ddbbbbcaaa3bdf7aac2c1a 310 Gene3D G3DSA:3.30.470.20 85 308 2.4E-78 T 23-10-2018 A0127_02245 d6dfc54239ddbbbbcaaa3bdf7aac2c1a 310 SUPERFAMILY SSF56059 99 310 3.18E-68 T 23-10-2018 A0127_02245 d6dfc54239ddbbbbcaaa3bdf7aac2c1a 310 SUPERFAMILY SSF52440 3 95 4.7E-31 T 23-10-2018 IPR016185 Pre-ATP-grasp domain superfamily A0127_02245 d6dfc54239ddbbbbcaaa3bdf7aac2c1a 310 Pfam PF06849 Protein of unknown function (DUF1246) 4 111 3.2E-33 T 23-10-2018 IPR010672 IMP biosynthesis enzyme PurP, N-terminal GO:0000287|GO:0005524|GO:0006188|GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 A0127_07170 aa5009b3ff279b088f5f7994b6b4e074 281 Pfam PF01026 TatD related DNase 5 275 7.3E-30 T 23-10-2018 IPR001130 TatD family GO:0016788 A0127_07170 aa5009b3ff279b088f5f7994b6b4e074 281 SUPERFAMILY SSF51556 1 278 2.59E-30 T 23-10-2018 IPR032466 Metal-dependent hydrolase A0127_07170 aa5009b3ff279b088f5f7994b6b4e074 281 ProDom PD038341 HYDROLASE COFACTOR MOLYBDENUM BIOSYNTHESIS METAL-DEPENDENT DEOXYRIBONUCLEASE PREDICTED TATD-RELATED TVG0313409 A 124 280 1.0E-83 T 23-10-2018 A0127_07170 aa5009b3ff279b088f5f7994b6b4e074 281 Gene3D G3DSA:3.20.20.140 3 280 2.4E-26 T 23-10-2018 A0127_07170 aa5009b3ff279b088f5f7994b6b4e074 281 PIRSF PIRSF004961 1 281 3.5E-123 T 23-10-2018 IPR011589 Protein of unknown function UCP004961 A0127_04665 765f2c460144efe4998b9befe97af415 183 Pfam PF01926 50S ribosome-binding GTPase 2 129 1.3E-17 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A0127_04665 765f2c460144efe4998b9befe97af415 183 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 2 177 7.5E-14 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A0127_04665 765f2c460144efe4998b9befe97af415 183 Hamap MF_00321 Probable GTP-binding protein EngB [engB]. 1 180 21.403 T 23-10-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 A0127_04665 765f2c460144efe4998b9befe97af415 183 SUPERFAMILY SSF52540 2 179 2.24E-30 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_04665 765f2c460144efe4998b9befe97af415 183 Gene3D G3DSA:3.40.50.300 1 182 1.3E-52 T 23-10-2018 A0127_02750 79d51f8903da21770b2383256636e9d3 225 PIRSF PIRSF005650 1 225 5.1E-61 T 23-10-2018 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 A0127_02750 79d51f8903da21770b2383256636e9d3 225 SUPERFAMILY SSF53633 1 224 6.28E-52 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily A0127_02750 79d51f8903da21770b2383256636e9d3 225 Hamap MF_01220_A Uridylate kinase [pyrH]. 1 225 34.99 T 23-10-2018 IPR011818 Uridylate kinase, archaeal/spirochete, putative GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 A0127_02750 79d51f8903da21770b2383256636e9d3 225 TIGRFAM TIGR02076 pyrH_arch: putative uridylate kinase 3 224 2.5E-87 T 23-10-2018 IPR011818 Uridylate kinase, archaeal/spirochete, putative GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 A0127_02750 79d51f8903da21770b2383256636e9d3 225 Gene3D G3DSA:3.40.1160.10 1 225 7.6E-62 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily A0127_02750 79d51f8903da21770b2383256636e9d3 225 Pfam PF00696 Amino acid kinase family 1 202 7.3E-35 T 23-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 A0127_03010 6954705dd39f0338e05437204b72a22f 713 Pfam PF02769 AIR synthase related protein, C-terminal domain 185 340 4.1E-35 T 23-10-2018 IPR010918 PurM-like, C-terminal domain A0127_03010 6954705dd39f0338e05437204b72a22f 713 Pfam PF02769 AIR synthase related protein, C-terminal domain 557 680 3.1E-19 T 23-10-2018 IPR010918 PurM-like, C-terminal domain A0127_03010 6954705dd39f0338e05437204b72a22f 713 SUPERFAMILY SSF56042 544 704 8.37E-36 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A0127_03010 6954705dd39f0338e05437204b72a22f 713 Gene3D G3DSA:3.90.650.10 12 341 9.8E-123 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A0127_03010 6954705dd39f0338e05437204b72a22f 713 PIRSF PIRSF001587 1 712 1.5E-284 T 23-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A0127_03010 6954705dd39f0338e05437204b72a22f 713 TIGRFAM TIGR01736 FGAM_synth_II: phosphoribosylformylglycinamidine synthase II 2 704 7.4E-294 T 23-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A0127_03010 6954705dd39f0338e05437204b72a22f 713 SUPERFAMILY SSF55326 19 178 2.69E-47 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A0127_03010 6954705dd39f0338e05437204b72a22f 713 SUPERFAMILY SSF56042 184 400 4.49E-49 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A0127_03010 6954705dd39f0338e05437204b72a22f 713 SUPERFAMILY SSF55326 378 534 3.27E-48 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A0127_03010 6954705dd39f0338e05437204b72a22f 713 Gene3D G3DSA:3.30.1330.10 27 175 9.8E-123 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A0127_03010 6954705dd39f0338e05437204b72a22f 713 Pfam PF00586 AIR synthase related protein, N-terminal domain 59 172 9.0E-25 T 23-10-2018 IPR016188 PurM-like, N-terminal domain A0127_03010 6954705dd39f0338e05437204b72a22f 713 Pfam PF00586 AIR synthase related protein, N-terminal domain 417 533 5.3E-20 T 23-10-2018 IPR016188 PurM-like, N-terminal domain A0127_03010 6954705dd39f0338e05437204b72a22f 713 Gene3D G3DSA:3.30.1330.10 368 537 1.2E-53 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A0127_03010 6954705dd39f0338e05437204b72a22f 713 Gene3D G3DSA:3.90.650.10 543 709 1.5E-36 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A0127_03010 6954705dd39f0338e05437204b72a22f 713 Hamap MF_00420 Phosphoribosylformylglycinamidine synthase subunit PurL [purL]. 1 713 255.434 T 23-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A0127_01405 81264a8f8005467dec2a05ea2cc623be 200 SUPERFAMILY SSF53335 3 189 6.91E-38 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A0127_01405 81264a8f8005467dec2a05ea2cc623be 200 Pfam PF08241 Methyltransferase domain 40 134 8.1E-26 T 23-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 A0127_01405 81264a8f8005467dec2a05ea2cc623be 200 ProSitePatterns PS01184 ubiE/COQ5 methyltransferase family signature 2. 124 138 - T 23-10-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 A0127_01405 81264a8f8005467dec2a05ea2cc623be 200 Gene3D G3DSA:3.40.50.150 12 189 1.0E-34 T 23-10-2018 A0127_08405 5b9cda3bb7fa4f518ecf496a3b6ab157 598 Pfam PF00009 Elongation factor Tu GTP binding domain 9 215 1.8E-32 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A0127_08405 5b9cda3bb7fa4f518ecf496a3b6ab157 598 SUPERFAMILY SSF52156 335 461 3.27E-35 T 23-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily A0127_08405 5b9cda3bb7fa4f518ecf496a3b6ab157 598 Pfam PF11987 Translation-initiation factor 2 352 447 2.0E-23 T 23-10-2018 IPR023115 Translation initiation factor IF- 2, domain 3 A0127_08405 5b9cda3bb7fa4f518ecf496a3b6ab157 598 Pfam PF14578 Elongation factor Tu domain 4 468 554 8.5E-30 T 23-10-2018 IPR029459 Elongation factor Tu-type domain A0127_08405 5b9cda3bb7fa4f518ecf496a3b6ab157 598 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 157 6.0E-20 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A0127_08405 5b9cda3bb7fa4f518ecf496a3b6ab157 598 Gene3D G3DSA:2.40.30.10 229 339 1.2E-40 T 23-10-2018 A0127_08405 5b9cda3bb7fa4f518ecf496a3b6ab157 598 Gene3D G3DSA:2.40.30.10 467 557 4.7E-31 T 23-10-2018 A0127_08405 5b9cda3bb7fa4f518ecf496a3b6ab157 598 PRINTS PR00315 GTP-binding elongation factor signature 9 22 1.6E-10 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A0127_08405 5b9cda3bb7fa4f518ecf496a3b6ab157 598 PRINTS PR00315 GTP-binding elongation factor signature 75 85 1.6E-10 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A0127_08405 5b9cda3bb7fa4f518ecf496a3b6ab157 598 PRINTS PR00315 GTP-binding elongation factor signature 91 102 1.6E-10 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A0127_08405 5b9cda3bb7fa4f518ecf496a3b6ab157 598 PRINTS PR00315 GTP-binding elongation factor signature 127 136 1.6E-10 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A0127_08405 5b9cda3bb7fa4f518ecf496a3b6ab157 598 SUPERFAMILY SSF52540 6 289 7.44E-56 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_08405 5b9cda3bb7fa4f518ecf496a3b6ab157 598 Pfam PF03144 Elongation factor Tu domain 2 248 326 2.1E-13 T 23-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 A0127_08405 5b9cda3bb7fa4f518ecf496a3b6ab157 598 Hamap MF_00100_A Translation initiation factor IF-2 [infB]. 3 597 43.985 T 23-10-2018 IPR004544 Translation initiation factor aIF-2, archaea GO:0003743|GO:0005525|GO:0005622|GO:0006413 A0127_08405 5b9cda3bb7fa4f518ecf496a3b6ab157 598 Gene3D G3DSA:3.40.50.10050 350 458 1.4E-36 T 23-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily A0127_08405 5b9cda3bb7fa4f518ecf496a3b6ab157 598 Gene3D G3DSA:3.40.50.300 2 228 4.3E-65 T 23-10-2018 A0127_08405 5b9cda3bb7fa4f518ecf496a3b6ab157 598 TIGRFAM TIGR00491 aIF-2: translation initiation factor aIF-2 4 595 1.1E-245 T 23-10-2018 IPR004544 Translation initiation factor aIF-2, archaea GO:0003743|GO:0005525|GO:0005622|GO:0006413 A0127_08405 5b9cda3bb7fa4f518ecf496a3b6ab157 598 SUPERFAMILY SSF50447 466 593 6.48E-26 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily A0127_00390 baa948e84c40a23121263b0792fde6ca 483 Pfam PF00733 Asparagine synthase 229 365 5.2E-36 T 23-10-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 A0127_00390 baa948e84c40a23121263b0792fde6ca 483 Pfam PF00733 Asparagine synthase 375 462 3.7E-16 T 23-10-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 A0127_00390 baa948e84c40a23121263b0792fde6ca 483 PIRSF PIRSF001589 364 483 1.1E-16 T 23-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 A0127_00390 baa948e84c40a23121263b0792fde6ca 483 PIRSF PIRSF001589 1 372 4.5E-63 T 23-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 A0127_00390 baa948e84c40a23121263b0792fde6ca 483 Gene3D G3DSA:3.40.50.620 222 480 8.0E-78 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A0127_00390 baa948e84c40a23121263b0792fde6ca 483 Gene3D G3DSA:3.60.20.10 2 221 3.9E-49 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A0127_00390 baa948e84c40a23121263b0792fde6ca 483 Pfam PF13537 Glutamine amidotransferase domain 61 179 1.9E-24 T 23-10-2018 IPR017932 Glutamine amidotransferase type 2 domain A0127_00390 baa948e84c40a23121263b0792fde6ca 483 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 364 2.2E-85 T 23-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 A0127_00390 baa948e84c40a23121263b0792fde6ca 483 SUPERFAMILY SSF52402 226 462 1.01E-59 T 23-10-2018 A0127_00390 baa948e84c40a23121263b0792fde6ca 483 SUPERFAMILY SSF56235 2 212 5.66E-42 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A0127_00010 0ac4a8e3252190757023bdeb031cca6b 592 SUPERFAMILY SSF54862 5 125 9.86E-24 T 23-10-2018 A0127_00010 0ac4a8e3252190757023bdeb031cca6b 592 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 52 63 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A0127_00010 0ac4a8e3252190757023bdeb031cca6b 592 Pfam PF04068 Possible Fer4-like domain in RNase L inhibitor, RLI 3 33 5.7E-11 T 23-10-2018 IPR007209 RNase L inhibitor RLI, possible metal-binding domain A0127_00010 0ac4a8e3252190757023bdeb031cca6b 592 Pfam PF00037 4Fe-4S binding domain 46 68 7.0E-7 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A0127_00010 0ac4a8e3252190757023bdeb031cca6b 592 SUPERFAMILY SSF52540 97 286 1.38E-33 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_00010 0ac4a8e3252190757023bdeb031cca6b 592 ProSitePatterns PS00211 ABC transporters family signature. 212 226 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A0127_00010 0ac4a8e3252190757023bdeb031cca6b 592 Pfam PF00005 ABC transporter 362 483 6.1E-21 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A0127_00010 0ac4a8e3252190757023bdeb031cca6b 592 PRINTS PR01868 ABC transporter family E signature 76 96 7.2E-63 T 23-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 A0127_00010 0ac4a8e3252190757023bdeb031cca6b 592 PRINTS PR01868 ABC transporter family E signature 49 73 7.2E-63 T 23-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 A0127_00010 0ac4a8e3252190757023bdeb031cca6b 592 PRINTS PR01868 ABC transporter family E signature 21 36 7.2E-63 T 23-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 A0127_00010 0ac4a8e3252190757023bdeb031cca6b 592 PRINTS PR01868 ABC transporter family E signature 104 129 7.2E-63 T 23-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 A0127_00010 0ac4a8e3252190757023bdeb031cca6b 592 PRINTS PR01868 ABC transporter family E signature 135 151 7.2E-63 T 23-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 A0127_00010 0ac4a8e3252190757023bdeb031cca6b 592 PRINTS PR01868 ABC transporter family E signature 151 177 7.2E-63 T 23-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 A0127_00010 0ac4a8e3252190757023bdeb031cca6b 592 Pfam PF00005 ABC transporter 97 239 1.7E-18 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A0127_00010 0ac4a8e3252190757023bdeb031cca6b 592 Gene3D G3DSA:3.40.50.300 1 327 5.9E-102 T 23-10-2018 A0127_00010 0ac4a8e3252190757023bdeb031cca6b 592 SUPERFAMILY SSF52540 361 530 7.7E-40 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_00010 0ac4a8e3252190757023bdeb031cca6b 592 Gene3D G3DSA:3.40.50.300 328 590 5.2E-67 T 23-10-2018 A0127_00010 0ac4a8e3252190757023bdeb031cca6b 592 SMART SM00382 364 532 6.1E-11 T 23-10-2018 IPR003593 AAA+ ATPase domain A0127_00010 0ac4a8e3252190757023bdeb031cca6b 592 SMART SM00382 99 289 1.0E-8 T 23-10-2018 IPR003593 AAA+ ATPase domain A0127_07035 4766d18060f0ae003060de9ec3f8174d 249 Pfam PF01138 3' exoribonuclease family, domain 1 25 154 9.8E-36 T 23-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A0127_07035 4766d18060f0ae003060de9ec3f8174d 249 TIGRFAM TIGR02065 ECX1: exosome complex exonuclease 1 9 238 2.0E-120 T 23-10-2018 IPR011807 Exosome complex component Rrp41 GO:0000178|GO:0006401|GO:0016896 A0127_07035 4766d18060f0ae003060de9ec3f8174d 249 SUPERFAMILY SSF54211 10 180 9.11E-48 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A0127_07035 4766d18060f0ae003060de9ec3f8174d 249 Pfam PF03725 3' exoribonuclease family, domain 2 157 222 1.1E-16 T 23-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A0127_07035 4766d18060f0ae003060de9ec3f8174d 249 Hamap MF_00591 Exosome complex component Rrp41 [rrp41]. 6 242 61.393 T 23-10-2018 IPR011807 Exosome complex component Rrp41 GO:0000178|GO:0006401|GO:0016896 A0127_07035 4766d18060f0ae003060de9ec3f8174d 249 SUPERFAMILY SSF55666 155 243 3.14E-26 T 23-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A0127_07035 4766d18060f0ae003060de9ec3f8174d 249 Gene3D G3DSA:3.30.230.70 24 249 1.8E-79 T 23-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A0127_03290 d9d9e8a2ba6d9fe2011f82a1ccf97e4f 172 Gene3D G3DSA:3.30.70.20 47 94 1.5E-12 T 23-10-2018 A0127_03290 d9d9e8a2ba6d9fe2011f82a1ccf97e4f 172 Pfam PF00037 4Fe-4S binding domain 67 88 3.7E-7 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A0127_03290 d9d9e8a2ba6d9fe2011f82a1ccf97e4f 172 SUPERFAMILY SSF54862 8 153 1.48E-19 T 23-10-2018 A0127_03290 d9d9e8a2ba6d9fe2011f82a1ccf97e4f 172 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 74 85 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A0127_06030 44faf8f621d5a191d70a6ec048fb05e1 99 Gene3D G3DSA:1.10.10.10 1 98 6.4E-26 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A0127_06030 44faf8f621d5a191d70a6ec048fb05e1 99 Pfam PF13601 Winged helix DNA-binding domain 17 94 4.2E-20 T 23-10-2018 IPR027395 Winged helix DNA-binding domain A0127_06030 44faf8f621d5a191d70a6ec048fb05e1 99 SUPERFAMILY SSF46785 11 97 6.11E-18 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A0127_06290 77b77c01c6fdea4c461aaeaed1d9945b 1006 TIGRFAM TIGR00348 hsdR: type I site-specific deoxyribonuclease, HsdR family 19 686 1.2E-183 T 23-10-2018 IPR004473 Restriction endonuclease, type I, HsdR GO:0003677|GO:0005524|GO:0009035|GO:0009307 A0127_06290 77b77c01c6fdea4c461aaeaed1d9945b 1006 Gene3D G3DSA:3.40.50.300 466 691 3.4E-40 T 23-10-2018 A0127_06290 77b77c01c6fdea4c461aaeaed1d9945b 1006 Pfam PF00271 Helicase conserved C-terminal domain 599 657 1.6E-4 T 23-10-2018 IPR001650 Helicase, C-terminal A0127_06290 77b77c01c6fdea4c461aaeaed1d9945b 1006 SUPERFAMILY SSF52540 220 501 7.77E-33 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_06290 77b77c01c6fdea4c461aaeaed1d9945b 1006 SMART SM00487 257 481 1.8E-11 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A0127_06290 77b77c01c6fdea4c461aaeaed1d9945b 1006 SUPERFAMILY SSF52540 288 711 6.73E-16 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_06290 77b77c01c6fdea4c461aaeaed1d9945b 1006 Gene3D G3DSA:3.40.50.300 260 462 8.9E-50 T 23-10-2018 A0127_06290 77b77c01c6fdea4c461aaeaed1d9945b 1006 Pfam PF04313 Type I restriction enzyme R protein N terminus (HSDR_N) 14 194 5.6E-39 T 23-10-2018 IPR007409 Restriction endonuclease, type I, HsdR, N-terminal GO:0003677|GO:0004519|GO:0006304 A0127_06290 77b77c01c6fdea4c461aaeaed1d9945b 1006 Pfam PF11867 Domain of unknown function (DUF3387) 731 968 6.9E-13 T 23-10-2018 IPR021810 Protein of unknown function DUF3387 A0127_06290 77b77c01c6fdea4c461aaeaed1d9945b 1006 Gene3D G3DSA:3.90.1570.50 97 257 1.5E-24 T 23-10-2018 A0127_06290 77b77c01c6fdea4c461aaeaed1d9945b 1006 Pfam PF04851 Type III restriction enzyme, res subunit 262 443 4.0E-21 T 23-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 A0127_05030 242eec44c306857e89b76e4998a68648 230 Pfam PF02663 FmdE, Molybdenum formylmethanofuran dehydrogenase operon 23 165 1.7E-36 T 23-10-2018 IPR003814 Formylmethanofuran dehydrogenase, subunit E domain A0127_05030 242eec44c306857e89b76e4998a68648 230 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 180 213 4.6E-9 T 23-10-2018 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 A0127_05030 242eec44c306857e89b76e4998a68648 230 PIRSF PIRSF006578 8 215 1.3E-49 T 23-10-2018 IPR026328 Formylmethanofuran dehydrogenase, subunit E A0127_05030 242eec44c306857e89b76e4998a68648 230 SUPERFAMILY SSF143555 13 181 6.8E-48 T 23-10-2018 A0127_05030 242eec44c306857e89b76e4998a68648 230 Gene3D G3DSA:3.30.1330.130 4 173 3.4E-42 T 23-10-2018 A0127_00295 1eea12d09f0fdcb4a73a97309897df2c 379 Pfam PF02005 N2,N2-dimethylguanosine tRNA methyltransferase 10 374 5.1E-116 T 23-10-2018 IPR002905 tRNA methyltransferase, Trm1 GO:0003723|GO:0004809|GO:0008033 MetaCyc: PWY-6829 A0127_00295 1eea12d09f0fdcb4a73a97309897df2c 379 Hamap MF_00290 tRNA (guanine(26)-N(2))-dimethyltransferase [trm1]. 4 375 43.562 T 23-10-2018 IPR022923 tRNA (guanine(26)-N(2))-dimethyltransferase, archaeal and bacterial GO:0004809 MetaCyc: PWY-6829 A0127_00295 1eea12d09f0fdcb4a73a97309897df2c 379 Gene3D G3DSA:3.40.50.150 1 316 6.3E-104 T 23-10-2018 A0127_00295 1eea12d09f0fdcb4a73a97309897df2c 379 TIGRFAM TIGR00308 TRM1: N2,N2-dimethylguanosine tRNA methyltransferase 6 377 1.7E-97 T 23-10-2018 IPR002905 tRNA methyltransferase, Trm1 GO:0003723|GO:0004809|GO:0008033 MetaCyc: PWY-6829 A0127_00295 1eea12d09f0fdcb4a73a97309897df2c 379 Gene3D G3DSA:3.30.56.70 317 376 5.0E-22 T 23-10-2018 A0127_00295 1eea12d09f0fdcb4a73a97309897df2c 379 SUPERFAMILY SSF53335 4 374 5.48E-109 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A0127_09725 87d1d19db7456dad4d0db42a95dda479 275 Gene3D G3DSA:1.10.150.190 86 171 2.4E-33 T 23-10-2018 IPR024054 Translation initiation factor 2, alpha subunit, middle domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-381042|Reactome: R-HSA-382556|Reactome: R-HSA-72649|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72731 A0127_09725 87d1d19db7456dad4d0db42a95dda479 275 SUPERFAMILY SSF50249 7 87 3.72E-21 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A0127_09725 87d1d19db7456dad4d0db42a95dda479 275 Pfam PF00575 S1 RNA binding domain 9 83 4.5E-13 T 23-10-2018 IPR003029 S1 domain GO:0003676 A0127_09725 87d1d19db7456dad4d0db42a95dda479 275 Hamap MF_00231 Translation initiation factor 2 subunit alpha [eif2a]. 3 263 33.976 T 23-10-2018 IPR022964 Translation initiation factor 2, alpha subunit, archaeal A0127_09725 87d1d19db7456dad4d0db42a95dda479 275 SMART SM00316 10 83 8.2E-25 T 23-10-2018 IPR022967 RNA-binding domain, S1 A0127_09725 87d1d19db7456dad4d0db42a95dda479 275 SUPERFAMILY SSF116742 85 174 4.32E-24 T 23-10-2018 IPR024054 Translation initiation factor 2, alpha subunit, middle domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-381042|Reactome: R-HSA-382556|Reactome: R-HSA-72649|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72731 A0127_09725 87d1d19db7456dad4d0db42a95dda479 275 SUPERFAMILY SSF110993 176 260 3.92E-22 T 23-10-2018 IPR024055 Translation initiation factor 2, alpha subunit, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-381042|Reactome: R-HSA-382556|Reactome: R-HSA-72649|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72731 A0127_09725 87d1d19db7456dad4d0db42a95dda479 275 Gene3D G3DSA:2.40.50.140 3 85 1.4E-31 T 23-10-2018 A0127_09725 87d1d19db7456dad4d0db42a95dda479 275 Gene3D G3DSA:3.30.70.1130 173 262 9.2E-33 T 23-10-2018 IPR024055 Translation initiation factor 2, alpha subunit, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-381042|Reactome: R-HSA-382556|Reactome: R-HSA-72649|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72731 A0127_09725 87d1d19db7456dad4d0db42a95dda479 275 Pfam PF07541 Eukaryotic translation initiation factor 2 alpha subunit 122 233 2.8E-23 T 23-10-2018 IPR011488 Translation initiation factor 2, alpha subunit GO:0003723|GO:0003743 Reactome: R-HSA-156827|Reactome: R-HSA-381042|Reactome: R-HSA-382556|Reactome: R-HSA-72649|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72731 A0127_08650 664053f7da0df666938c25b597cb1c05 200 SMART SM01397 8 198 6.9E-101 T 23-10-2018 IPR001593 Ribosomal protein S3Ae GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_08650 664053f7da0df666938c25b597cb1c05 200 Hamap MF_00359 30S ribosomal protein S3Ae [rps3ae]. 8 198 36.937 T 23-10-2018 IPR030838 30S ribosomal protein S3Ae GO:0003735|GO:0005840|GO:0006412 A0127_08650 664053f7da0df666938c25b597cb1c05 200 Pfam PF01015 Ribosomal S3Ae family 11 198 2.0E-66 T 23-10-2018 IPR001593 Ribosomal protein S3Ae GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_08650 664053f7da0df666938c25b597cb1c05 200 ProSitePatterns PS01191 Ribosomal protein S3Ae signature. 47 59 - T 23-10-2018 IPR018281 Ribosomal protein S3Ae, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_07430 df53b1a5c0780804538df0b82325be7f 385 Gene3D G3DSA:3.40.640.10 35 280 6.9E-137 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A0127_07430 df53b1a5c0780804538df0b82325be7f 385 Gene3D G3DSA:3.90.1150.10 25 379 6.9E-137 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A0127_07430 df53b1a5c0780804538df0b82325be7f 385 Pfam PF00266 Aminotransferase class-V 45 369 1.1E-41 T 23-10-2018 IPR000192 Aminotransferase class V domain A0127_07430 df53b1a5c0780804538df0b82325be7f 385 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 202 222 - T 23-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site A0127_07430 df53b1a5c0780804538df0b82325be7f 385 PIRSF PIRSF000524 17 385 2.0E-102 T 23-10-2018 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832|Reactome: R-HSA-389661|Reactome: R-HSA-9033241 A0127_07430 df53b1a5c0780804538df0b82325be7f 385 SUPERFAMILY SSF53383 22 383 4.57E-96 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A0127_03735 fb57c05f656109ef9e74d09a58470fac 119 Hamap MF_00757 Ribonuclease P protein component 4 [rnp4]. 10 109 26.399 T 23-10-2018 IPR016432 Ribonuclease P, protein component 4 GO:0001682|GO:0004526 A0127_03735 fb57c05f656109ef9e74d09a58470fac 119 PIRSF PIRSF004878 1 116 2.1E-44 T 23-10-2018 IPR016432 Ribonuclease P, protein component 4 GO:0001682|GO:0004526 A0127_03735 fb57c05f656109ef9e74d09a58470fac 119 Gene3D G3DSA:1.20.5.420 6 63 2.8E-22 T 23-10-2018 A0127_03735 fb57c05f656109ef9e74d09a58470fac 119 Pfam PF04032 RNAse P Rpr2/Rpp21/SNM1 subunit domain 21 100 7.6E-17 T 23-10-2018 IPR007175 RNAse P, Rpr2/Rpp21 subunit Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 A0127_03735 fb57c05f656109ef9e74d09a58470fac 119 Gene3D G3DSA:2.20.25.200 64 119 7.2E-27 T 23-10-2018 A0127_10160 50c2d7e2d2b4aa11cea5bef76d2760e0 666 Gene3D G3DSA:3.40.1110.10 370 488 8.8E-99 T 23-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 A0127_10160 50c2d7e2d2b4aa11cea5bef76d2760e0 666 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 359 373 6.2E-29 T 23-10-2018 A0127_10160 50c2d7e2d2b4aa11cea5bef76d2760e0 666 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 579 591 6.2E-29 T 23-10-2018 A0127_10160 50c2d7e2d2b4aa11cea5bef76d2760e0 666 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 481 492 6.2E-29 T 23-10-2018 A0127_10160 50c2d7e2d2b4aa11cea5bef76d2760e0 666 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 556 575 6.2E-29 T 23-10-2018 A0127_10160 50c2d7e2d2b4aa11cea5bef76d2760e0 666 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 503 513 6.2E-29 T 23-10-2018 A0127_10160 50c2d7e2d2b4aa11cea5bef76d2760e0 666 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 209 223 6.2E-29 T 23-10-2018 A0127_10160 50c2d7e2d2b4aa11cea5bef76d2760e0 666 SUPERFAMILY SSF81665 95 613 1.96E-12 T 23-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 A0127_10160 50c2d7e2d2b4aa11cea5bef76d2760e0 666 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 361 367 - T 23-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 A0127_10160 50c2d7e2d2b4aa11cea5bef76d2760e0 666 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 125 661 5.8E-120 T 23-10-2018 A0127_10160 50c2d7e2d2b4aa11cea5bef76d2760e0 666 SUPERFAMILY SSF56784 357 661 2.2E-61 T 23-10-2018 IPR036412 HAD-like superfamily A0127_10160 50c2d7e2d2b4aa11cea5bef76d2760e0 666 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 80 665 4.2E-196 T 23-10-2018 A0127_10160 50c2d7e2d2b4aa11cea5bef76d2760e0 666 Gene3D G3DSA:2.70.150.20 147 263 3.6E-40 T 23-10-2018 A0127_10160 50c2d7e2d2b4aa11cea5bef76d2760e0 666 Gene3D G3DSA:3.40.50.1000 353 606 8.8E-99 T 23-10-2018 IPR023214 HAD superfamily A0127_10160 50c2d7e2d2b4aa11cea5bef76d2760e0 666 SUPERFAMILY SSF81653 162 259 1.03E-27 T 23-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 A0127_10160 50c2d7e2d2b4aa11cea5bef76d2760e0 666 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 556 572 4.3E-10 T 23-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A0127_10160 50c2d7e2d2b4aa11cea5bef76d2760e0 666 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 403 421 4.3E-10 T 23-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A0127_10160 50c2d7e2d2b4aa11cea5bef76d2760e0 666 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 587 612 4.3E-10 T 23-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A0127_10160 50c2d7e2d2b4aa11cea5bef76d2760e0 666 Pfam PF00702 haloacid dehalogenase-like hydrolase 355 570 7.3E-45 T 23-10-2018 A0127_10160 50c2d7e2d2b4aa11cea5bef76d2760e0 666 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 98 663 7.1E-193 T 23-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 A0127_10160 50c2d7e2d2b4aa11cea5bef76d2760e0 666 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 135 636 3.0E-96 T 23-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 A0127_10160 50c2d7e2d2b4aa11cea5bef76d2760e0 666 Pfam PF00122 E1-E2 ATPase 159 337 2.5E-52 T 23-10-2018 A0127_02630 5e4ff797fc432f1b3eabafaeeb723a98 331 SMART SM00797 23 300 2.5E-131 T 23-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B A0127_02630 5e4ff797fc432f1b3eabafaeeb723a98 331 Gene3D G3DSA:2.40.100.10 172 311 6.6E-50 T 23-10-2018 IPR029000 Cyclophilin-like domain superfamily A0127_02630 5e4ff797fc432f1b3eabafaeeb723a98 331 TIGRFAM TIGR00724 urea_amlyse_rel: biotin-dependent carboxylase uncharacterized domain 2 309 1.3E-101 T 23-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B A0127_02630 5e4ff797fc432f1b3eabafaeeb723a98 331 Pfam PF02626 Carboxyltransferase domain, subdomain A and B 24 283 8.2E-82 T 23-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B A0127_02630 5e4ff797fc432f1b3eabafaeeb723a98 331 SUPERFAMILY SSF50891 173 290 7.21E-11 T 23-10-2018 IPR029000 Cyclophilin-like domain superfamily A0127_01510 2272c027267788f70647892e20e27e4f 199 SUPERFAMILY SSF54001 43 195 2.8E-25 T 23-10-2018 IPR038765 Papain-like cysteine peptidase superfamily A0127_01510 2272c027267788f70647892e20e27e4f 199 Gene3D G3DSA:3.90.1720.10 53 197 1.6E-14 T 23-10-2018 A0127_01510 2272c027267788f70647892e20e27e4f 199 Pfam PF05708 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family 43 195 5.1E-25 T 23-10-2018 IPR024453 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family A0127_08605 164513e80a59eb45e8bc03d881948bb8 192 PIRSF PIRSF037253 2 190 5.7E-85 T 23-10-2018 IPR017158 Transcription regulator, CBS domain-containing, predicted A0127_08605 164513e80a59eb45e8bc03d881948bb8 192 Gene3D G3DSA:3.10.580.10 65 186 6.9E-28 T 23-10-2018 A0127_08605 164513e80a59eb45e8bc03d881948bb8 192 Pfam PF01381 Helix-turn-helix 13 60 2.2E-15 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A0127_08605 164513e80a59eb45e8bc03d881948bb8 192 SUPERFAMILY SSF54631 69 184 1.39E-27 T 23-10-2018 A0127_08605 164513e80a59eb45e8bc03d881948bb8 192 Gene3D G3DSA:1.10.260.40 10 63 3.3E-17 T 23-10-2018 A0127_08605 164513e80a59eb45e8bc03d881948bb8 192 SMART SM00530 12 66 4.0E-14 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A0127_08605 164513e80a59eb45e8bc03d881948bb8 192 SUPERFAMILY SSF47413 11 60 1.39E-14 T 23-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A0127_08605 164513e80a59eb45e8bc03d881948bb8 192 Pfam PF00571 CBS domain 134 184 3.0E-7 T 23-10-2018 IPR000644 CBS domain A0127_08605 164513e80a59eb45e8bc03d881948bb8 192 Pfam PF00571 CBS domain 70 121 8.5E-14 T 23-10-2018 IPR000644 CBS domain A0127_08605 164513e80a59eb45e8bc03d881948bb8 192 SMART SM00116 141 187 0.19 T 23-10-2018 IPR000644 CBS domain A0127_08605 164513e80a59eb45e8bc03d881948bb8 192 SMART SM00116 77 124 7.8E-9 T 23-10-2018 IPR000644 CBS domain A0127_01100 032aaa0ee72d9b85cdeb9e9f4c971f35 385 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 106 117 7.8E-29 T 23-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 A0127_01100 032aaa0ee72d9b85cdeb9e9f4c971f35 385 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 201 218 7.8E-29 T 23-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 A0127_01100 032aaa0ee72d9b85cdeb9e9f4c971f35 385 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 146 161 7.8E-29 T 23-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 A0127_01100 032aaa0ee72d9b85cdeb9e9f4c971f35 385 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 257 273 7.8E-29 T 23-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 A0127_01100 032aaa0ee72d9b85cdeb9e9f4c971f35 385 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 225 246 7.8E-29 T 23-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 A0127_01100 032aaa0ee72d9b85cdeb9e9f4c971f35 385 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 128 145 7.8E-29 T 23-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 A0127_01100 032aaa0ee72d9b85cdeb9e9f4c971f35 385 Pfam PF04406 Type IIB DNA topoisomerase 82 151 1.5E-19 T 23-10-2018 IPR013049 Spo11/DNA topoisomerase VI, subunit A, N-terminal GO:0003677|GO:0003824|GO:0005524|GO:0005694|GO:0006259 Reactome: R-HSA-912446 A0127_01100 032aaa0ee72d9b85cdeb9e9f4c971f35 385 Gene3D G3DSA:1.10.10.10 11 154 3.1E-52 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A0127_01100 032aaa0ee72d9b85cdeb9e9f4c971f35 385 Hamap MF_00132 Type 2 DNA topoisomerase 6 subunit A [top6A]. 16 384 40.113 T 23-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 A0127_01100 032aaa0ee72d9b85cdeb9e9f4c971f35 385 Gene3D G3DSA:3.40.1360.10 155 384 8.9E-65 T 23-10-2018 A0127_01100 032aaa0ee72d9b85cdeb9e9f4c971f35 385 SUPERFAMILY SSF56726 81 383 7.85E-79 T 23-10-2018 IPR036078 Spo11/DNA topoisomerase VI subunit A superfamily GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 A0127_01100 032aaa0ee72d9b85cdeb9e9f4c971f35 385 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 355 378 2.4E-49 T 23-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 A0127_01100 032aaa0ee72d9b85cdeb9e9f4c971f35 385 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 231 251 2.4E-49 T 23-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 A0127_01100 032aaa0ee72d9b85cdeb9e9f4c971f35 385 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 122 139 2.4E-49 T 23-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 A0127_01100 032aaa0ee72d9b85cdeb9e9f4c971f35 385 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 48 68 2.4E-49 T 23-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 A0127_01100 032aaa0ee72d9b85cdeb9e9f4c971f35 385 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 175 193 2.4E-49 T 23-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 A0127_03240 d4000b0ead2efc72edb70b80c448cd06 337 Pfam PF11536 Protein of unknown function (DUF3226) 100 335 1.4E-99 T 23-10-2018 IPR024508 Protein of unknown function DUF3226 A0127_03240 d4000b0ead2efc72edb70b80c448cd06 337 SUPERFAMILY SSF160945 99 333 9.29E-90 T 23-10-2018 A0127_03240 d4000b0ead2efc72edb70b80c448cd06 337 Gene3D G3DSA:1.10.3490.10 234 318 8.2E-78 T 23-10-2018 A0127_03240 d4000b0ead2efc72edb70b80c448cd06 337 ProDom PD038575 MJECL12 PLASMID PH0156 100 321 5.0E-120 T 23-10-2018 IPR024508 Protein of unknown function DUF3226 A0127_03240 d4000b0ead2efc72edb70b80c448cd06 337 Gene3D G3DSA:3.40.50.10620 100 233 8.2E-78 T 23-10-2018 A0127_06750 84ff406e25002d40cea55b4304ad3a0d 190 Gene3D G3DSA:2.40.50.140 82 190 4.8E-34 T 23-10-2018 A0127_06750 84ff406e25002d40cea55b4304ad3a0d 190 Pfam PF03876 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 8 77 1.9E-18 T 23-10-2018 IPR005576 RNA polymerase Rpb7, N-terminal GO:0003899|GO:0006351 A0127_06750 84ff406e25002d40cea55b4304ad3a0d 190 Pfam PF00575 S1 RNA binding domain 78 154 1.9E-15 T 23-10-2018 IPR003029 S1 domain GO:0003676 A0127_06750 84ff406e25002d40cea55b4304ad3a0d 190 TIGRFAM TIGR00448 rpoE: DNA-directed RNA polymerase 1 179 9.8E-66 T 23-10-2018 IPR004519 DNA-directed RNA polymerase, subunit E/RPC8 GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-1834949|Reactome: R-HSA-73780|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071 A0127_06750 84ff406e25002d40cea55b4304ad3a0d 190 Gene3D G3DSA:3.30.1490.120 1 80 8.7E-32 T 23-10-2018 IPR036898 RNA polymerase Rpb7-like, N-terminal domain superfamily GO:0003899|GO:0006351 A0127_06750 84ff406e25002d40cea55b4304ad3a0d 190 SUPERFAMILY SSF88798 1 77 1.44E-20 T 23-10-2018 IPR036898 RNA polymerase Rpb7-like, N-terminal domain superfamily GO:0003899|GO:0006351 A0127_06750 84ff406e25002d40cea55b4304ad3a0d 190 SMART SM00316 80 166 4.7E-18 T 23-10-2018 IPR022967 RNA-binding domain, S1 A0127_06750 84ff406e25002d40cea55b4304ad3a0d 190 SUPERFAMILY SSF50249 80 179 5.97E-25 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A0127_05570 7782a69612682cc0b22e9cb9edcf8a6a 440 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 148 285 4.9E-57 T 23-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain A0127_05570 7782a69612682cc0b22e9cb9edcf8a6a 440 SUPERFAMILY SSF52210 130 285 6.41E-44 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A0127_05570 7782a69612682cc0b22e9cb9edcf8a6a 440 Gene3D G3DSA:3.40.50.261 289 440 6.1E-52 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A0127_05570 7782a69612682cc0b22e9cb9edcf8a6a 440 Pfam PF13380 CoA binding domain 11 131 4.5E-16 T 23-10-2018 IPR003781 CoA-binding GO:0048037 A0127_05570 7782a69612682cc0b22e9cb9edcf8a6a 440 Gene3D G3DSA:3.40.50.261 136 288 1.1E-59 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A0127_05570 7782a69612682cc0b22e9cb9edcf8a6a 440 Gene3D G3DSA:3.40.50.720 1 127 4.2E-31 T 23-10-2018 A0127_05570 7782a69612682cc0b22e9cb9edcf8a6a 440 SUPERFAMILY SSF52210 292 438 1.44E-38 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A0127_05570 7782a69612682cc0b22e9cb9edcf8a6a 440 SMART SM00881 6 100 2.0E-19 T 23-10-2018 IPR003781 CoA-binding GO:0048037 A0127_05570 7782a69612682cc0b22e9cb9edcf8a6a 440 SUPERFAMILY SSF51735 2 133 9.95E-23 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A0127_00525 45e95a4ec01b3540a4dd3186e6e83570 350 Gene3D G3DSA:3.90.180.10 21 338 7.1E-136 T 23-10-2018 A0127_00525 45e95a4ec01b3540a4dd3186e6e83570 350 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 138 2.5E-36 T 23-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 A0127_00525 45e95a4ec01b3540a4dd3186e6e83570 350 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 66 80 - T 23-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 A0127_00525 45e95a4ec01b3540a4dd3186e6e83570 350 SMART SM00829 16 345 1.2E-6 T 23-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 A0127_00525 45e95a4ec01b3540a4dd3186e6e83570 350 SUPERFAMILY SSF51735 146 310 4.21E-34 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A0127_00525 45e95a4ec01b3540a4dd3186e6e83570 350 SUPERFAMILY SSF50129 3 177 1.31E-54 T 23-10-2018 IPR011032 GroES-like superfamily A0127_00525 45e95a4ec01b3540a4dd3186e6e83570 350 Gene3D G3DSA:3.40.50.720 157 291 7.1E-136 T 23-10-2018 A0127_00525 45e95a4ec01b3540a4dd3186e6e83570 350 TIGRFAM TIGR00692 tdh: L-threonine 3-dehydrogenase 7 346 2.3E-180 T 23-10-2018 IPR004627 L-threonine 3-dehydrogenase GO:0006567|GO:0008270|GO:0008743|GO:0055114 KEGG: 00260+1.1.1.103|MetaCyc: PWY-7378 A0127_00525 45e95a4ec01b3540a4dd3186e6e83570 350 Pfam PF00107 Zinc-binding dehydrogenase 178 306 1.7E-28 T 23-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 A0127_00525 45e95a4ec01b3540a4dd3186e6e83570 350 Hamap MF_00627 L-threonine 3-dehydrogenase [tdh]. 5 347 54.304 T 23-10-2018 IPR004627 L-threonine 3-dehydrogenase GO:0006567|GO:0008270|GO:0008743|GO:0055114 KEGG: 00260+1.1.1.103|MetaCyc: PWY-7378 A0127_00040 0e50af743c961e95d261188b665d20d5 279 Gene3D G3DSA:3.30.1360.130 118 263 1.6E-75 T 23-10-2018 A0127_00040 0e50af743c961e95d261188b665d20d5 279 Gene3D G3DSA:3.40.50.10780 1 217 1.6E-75 T 23-10-2018 IPR027476 D-aminopeptidase, N-terminal A0127_00040 0e50af743c961e95d261188b665d20d5 279 PIRSF PIRSF015853 1 277 6.3E-101 T 23-10-2018 IPR007035 Peptidase M55, D-aminopeptidase A0127_00040 0e50af743c961e95d261188b665d20d5 279 Pfam PF04951 D-aminopeptidase 1 265 1.3E-83 T 23-10-2018 IPR007035 Peptidase M55, D-aminopeptidase A0127_00040 0e50af743c961e95d261188b665d20d5 279 SUPERFAMILY SSF63992 1 275 4.58E-85 T 23-10-2018 IPR036177 Peptidase M55, D-aminopeptidase superfamily A0127_03915 3c1838996795b6b2b4d4bb59eebf184a 67 Pfam PF00833 Ribosomal S17 1 64 2.1E-15 T 23-10-2018 IPR001210 Ribosomal protein S17e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_03915 3c1838996795b6b2b4d4bb59eebf184a 67 Gene3D G3DSA:1.10.60.20 1 62 4.2E-29 T 23-10-2018 IPR036401 Ribosomal protein S17e-like superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_03915 3c1838996795b6b2b4d4bb59eebf184a 67 SUPERFAMILY SSF116820 1 60 1.09E-23 T 23-10-2018 IPR036401 Ribosomal protein S17e-like superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_03915 3c1838996795b6b2b4d4bb59eebf184a 67 Hamap MF_00511 30S ribosomal protein S17e [rps17e]. 1 63 22.421 T 23-10-2018 IPR001210 Ribosomal protein S17e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_03915 3c1838996795b6b2b4d4bb59eebf184a 67 ProSitePatterns PS00712 Ribosomal protein S17e signature. 41 56 - T 23-10-2018 IPR018273 Ribosomal protein S17e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_06070 58c0a9a91d72d5c83fccf7323d40b0ba 286 Pfam PF16916 Dimerisation domain of Zinc Transporter 208 280 8.0E-23 T 23-10-2018 IPR027470 Cation efflux protein, cytoplasmic domain A0127_06070 58c0a9a91d72d5c83fccf7323d40b0ba 286 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 6 281 9.6E-82 T 23-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 A0127_06070 58c0a9a91d72d5c83fccf7323d40b0ba 286 Gene3D G3DSA:1.20.1510.10 4 200 5.6E-62 T 23-10-2018 IPR027469 Cation efflux transmembrane domain superfamily A0127_06070 58c0a9a91d72d5c83fccf7323d40b0ba 286 Gene3D G3DSA:3.30.70.1350 207 282 8.2E-22 T 23-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 A0127_06070 58c0a9a91d72d5c83fccf7323d40b0ba 286 SUPERFAMILY SSF160240 205 280 6.41E-22 T 23-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 A0127_06070 58c0a9a91d72d5c83fccf7323d40b0ba 286 SUPERFAMILY SSF161111 5 202 8.76E-57 T 23-10-2018 IPR027469 Cation efflux transmembrane domain superfamily A0127_06070 58c0a9a91d72d5c83fccf7323d40b0ba 286 Pfam PF01545 Cation efflux family 8 200 2.0E-47 T 23-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 A0127_02700 fe9ca8cfd2a14755dafe5b20f7f503c5 359 Pfam PF01546 Peptidase family M20/M25/M40 64 341 4.8E-25 T 23-10-2018 IPR002933 Peptidase M20 GO:0016787 A0127_02700 fe9ca8cfd2a14755dafe5b20f7f503c5 359 Pfam PF07687 Peptidase dimerisation domain 152 257 1.1E-8 T 23-10-2018 IPR011650 Peptidase M20, dimerisation domain A0127_02700 fe9ca8cfd2a14755dafe5b20f7f503c5 359 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 87 124 - T 23-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 A0127_02700 fe9ca8cfd2a14755dafe5b20f7f503c5 359 SUPERFAMILY SSF55031 155 271 4.19E-11 T 23-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain A0127_02700 fe9ca8cfd2a14755dafe5b20f7f503c5 359 Gene3D G3DSA:3.40.630.10 14 336 5.9E-61 T 23-10-2018 A0127_02700 fe9ca8cfd2a14755dafe5b20f7f503c5 359 Gene3D G3DSA:3.30.70.360 155 264 5.9E-61 T 23-10-2018 A0127_02700 fe9ca8cfd2a14755dafe5b20f7f503c5 359 SUPERFAMILY SSF53187 8 342 1.66E-41 T 23-10-2018 A0127_03405 1896d2f4516cebfe19d2cdc1d2e8b34a 288 Pfam PF17284 Spermidine synthase tetramerisation domain 10 60 7.4E-14 T 23-10-2018 IPR035246 Spermidine synthase, tetramerisation domain KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 A0127_03405 1896d2f4516cebfe19d2cdc1d2e8b34a 288 Hamap MF_00198 Polyamine aminopropyltransferase [speE]. 8 286 36.237 T 23-10-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 A0127_03405 1896d2f4516cebfe19d2cdc1d2e8b34a 288 ProSitePatterns PS01330 Polyamine biosynthesis (PABS) domain signature. 84 97 - T 23-10-2018 IPR030373 Polyamine biosynthesis domain, conserved site KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 A0127_03405 1896d2f4516cebfe19d2cdc1d2e8b34a 288 SUPERFAMILY SSF53335 9 286 8.97E-75 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A0127_03405 1896d2f4516cebfe19d2cdc1d2e8b34a 288 Pfam PF01564 Spermine/spermidine synthase domain 64 247 8.5E-49 T 23-10-2018 A0127_03405 1896d2f4516cebfe19d2cdc1d2e8b34a 288 TIGRFAM TIGR00417 speE: spermidine synthase 10 280 1.8E-79 T 23-10-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 A0127_03405 1896d2f4516cebfe19d2cdc1d2e8b34a 288 Gene3D G3DSA:3.40.50.150 62 287 2.5E-75 T 23-10-2018 A0127_03405 1896d2f4516cebfe19d2cdc1d2e8b34a 288 Gene3D G3DSA:2.30.140.10 6 60 3.5E-24 T 23-10-2018 IPR037163 Spermidine synthase, tetramerisation domain superfamily KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 A0127_07765 0eeb6e9973da38fb6e2610178d52b252 79 SUPERFAMILY SSF54909 2 74 1.05E-15 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel A0127_07765 0eeb6e9973da38fb6e2610178d52b252 79 Gene3D G3DSA:3.30.70.920 1 74 2.3E-22 T 23-10-2018 A0127_07765 0eeb6e9973da38fb6e2610178d52b252 79 Pfam PF01037 Lrp/AsnC ligand binding domain 6 74 2.5E-16 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A0127_05025 5dd34eba6a31df2733613cd9a1c98b8d 331 Gene3D G3DSA:3.40.50.970 12 97 7.6E-11 T 23-10-2018 A0127_05025 5dd34eba6a31df2733613cd9a1c98b8d 331 Gene3D G3DSA:3.40.50.970 98 321 2.7E-68 T 23-10-2018 A0127_05025 5dd34eba6a31df2733613cd9a1c98b8d 331 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 57 218 3.0E-26 T 23-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 A0127_05025 5dd34eba6a31df2733613cd9a1c98b8d 331 SUPERFAMILY SSF52518 12 318 2.49E-76 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold A0127_04105 20e12ce5622d8ad690bd3537bd1fdb0b 249 Gene3D G3DSA:3.30.70.1890 1 121 3.9E-41 T 23-10-2018 A0127_04105 20e12ce5622d8ad690bd3537bd1fdb0b 249 Pfam PF01881 CRISPR associated protein Cas6 94 238 3.3E-33 T 23-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 A0127_04105 20e12ce5622d8ad690bd3537bd1fdb0b 249 Gene3D G3DSA:3.30.70.1900 123 242 2.2E-38 T 23-10-2018 A0127_04105 20e12ce5622d8ad690bd3537bd1fdb0b 249 PIRSF PIRSF005054 1 242 2.1E-69 T 23-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 A0127_04105 20e12ce5622d8ad690bd3537bd1fdb0b 249 TIGRFAM TIGR01877 cas_cas6: CRISPR-associated endoribonuclease Cas6 50 237 1.9E-44 T 23-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 A0127_06325 b9cf93b5a5e05a4f1b71633620739f34 456 Gene3D G3DSA:3.40.120.10 1 144 1.4E-45 T 23-10-2018 A0127_06325 b9cf93b5a5e05a4f1b71633620739f34 456 Gene3D G3DSA:3.30.310.50 346 450 3.1E-19 T 23-10-2018 A0127_06325 b9cf93b5a5e05a4f1b71633620739f34 456 SUPERFAMILY SSF55957 343 445 1.1E-21 T 23-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A0127_06325 b9cf93b5a5e05a4f1b71633620739f34 456 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 2 129 3.7E-38 T 23-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A0127_06325 b9cf93b5a5e05a4f1b71633620739f34 456 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 249 353 1.0E-4 T 23-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A0127_06325 b9cf93b5a5e05a4f1b71633620739f34 456 Gene3D G3DSA:3.40.120.10 160 342 1.7E-46 T 23-10-2018 A0127_06325 b9cf93b5a5e05a4f1b71633620739f34 456 SUPERFAMILY SSF53738 147 247 1.22E-27 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A0127_06325 b9cf93b5a5e05a4f1b71633620739f34 456 SUPERFAMILY SSF53738 2 168 1.37E-41 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A0127_06325 b9cf93b5a5e05a4f1b71633620739f34 456 SUPERFAMILY SSF53738 248 350 3.26E-11 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A0127_06325 b9cf93b5a5e05a4f1b71633620739f34 456 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 369 435 2.8E-12 T 23-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A0127_06325 b9cf93b5a5e05a4f1b71633620739f34 456 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 87 96 - T 23-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A0127_06325 b9cf93b5a5e05a4f1b71633620739f34 456 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 162 181 7.8E-16 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A0127_06325 b9cf93b5a5e05a4f1b71633620739f34 456 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 86 100 7.8E-16 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A0127_06325 b9cf93b5a5e05a4f1b71633620739f34 456 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 224 239 7.8E-16 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A0127_06325 b9cf93b5a5e05a4f1b71633620739f34 456 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 196 209 7.8E-16 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A0127_06325 b9cf93b5a5e05a4f1b71633620739f34 456 TIGRFAM TIGR03990 Arch_GlmM: phosphoglucosamine mutase 1 440 1.0E-149 T 23-10-2018 IPR024086 Phosphoglucosamine mutase, archaeal type GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A0127_06325 b9cf93b5a5e05a4f1b71633620739f34 456 Gene3D G3DSA:3.40.120.10 245 345 1.7E-46 T 23-10-2018 A0127_06325 b9cf93b5a5e05a4f1b71633620739f34 456 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 148 244 3.0E-25 T 23-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A0127_01610 147241de319f4171382add7fb61cc5b4 465 TIGRFAM TIGR02717 AcCoA-syn-alpha: acetyl coenzyme A synthetase (ADP forming), alpha domain 7 455 3.8E-187 T 23-10-2018 IPR014089 Acetate-CoA ligase [ADP-forming], alpha domain KEGG: 00010+6.2.1.13|KEGG: 00620+6.2.1.13|KEGG: 00640+6.2.1.13|MetaCyc: PWY-5483|MetaCyc: PWY-5535 A0127_01610 147241de319f4171382add7fb61cc5b4 465 Gene3D G3DSA:3.40.50.720 4 137 3.0E-45 T 23-10-2018 A0127_01610 147241de319f4171382add7fb61cc5b4 465 SMART SM00881 9 108 1.8E-39 T 23-10-2018 IPR003781 CoA-binding GO:0048037 A0127_01610 147241de319f4171382add7fb61cc5b4 465 Gene3D G3DSA:3.40.50.261 300 465 2.5E-50 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A0127_01610 147241de319f4171382add7fb61cc5b4 465 Gene3D G3DSA:3.40.50.261 138 299 2.3E-66 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A0127_01610 147241de319f4171382add7fb61cc5b4 465 Pfam PF13380 CoA binding domain 13 142 1.4E-20 T 23-10-2018 IPR003781 CoA-binding GO:0048037 A0127_01610 147241de319f4171382add7fb61cc5b4 465 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 159 296 2.2E-57 T 23-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain A0127_01610 147241de319f4171382add7fb61cc5b4 465 SUPERFAMILY SSF52210 139 298 3.27E-45 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A0127_01610 147241de319f4171382add7fb61cc5b4 465 SUPERFAMILY SSF52210 302 460 1.15E-33 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A0127_01610 147241de319f4171382add7fb61cc5b4 465 SUPERFAMILY SSF51735 6 137 2.89E-38 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A0127_08485 5e6dc316b4f7bf315e3e2215485293d4 205 Gene3D G3DSA:3.40.50.620 1 200 1.0E-64 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A0127_08485 5e6dc316b4f7bf315e3e2215485293d4 205 SUPERFAMILY SSF52402 1 146 8.6E-24 T 23-10-2018 A0127_08485 5e6dc316b4f7bf315e3e2215485293d4 205 Pfam PF00733 Asparagine synthase 8 68 3.1E-5 T 23-10-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 A0127_01825 65cac131d1f6d761a3e02db7e1e9a664 441 SUPERFAMILY SSF111283 2 439 2.09E-94 T 23-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 A0127_01825 65cac131d1f6d761a3e02db7e1e9a664 441 Gene3D G3DSA:3.30.2290.10 1 206 8.6E-19 T 23-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal A0127_01825 65cac131d1f6d761a3e02db7e1e9a664 441 Pfam PF01523 Putative modulator of DNA gyrase 15 304 4.5E-46 T 23-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 A0127_07770 5e0bfe5472087406cf31f1519c7e844b 448 SMART SM00963 2 87 2.8E-24 T 23-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A0127_07770 5e0bfe5472087406cf31f1519c7e844b 448 SUPERFAMILY SSF47446 297 429 8.5E-44 T 23-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 A0127_07770 5e0bfe5472087406cf31f1519c7e844b 448 Gene3D G3DSA:1.20.120.140 6 305 7.5E-124 T 23-10-2018 A0127_07770 5e0bfe5472087406cf31f1519c7e844b 448 SUPERFAMILY SSF47364 1 94 2.36E-24 T 23-10-2018 IPR036225 SRP/SRP receptor, N-terminal Reactome: R-HSA-1799339 A0127_07770 5e0bfe5472087406cf31f1519c7e844b 448 SMART SM00382 99 300 3.9E-6 T 23-10-2018 IPR003593 AAA+ ATPase domain A0127_07770 5e0bfe5472087406cf31f1519c7e844b 448 Gene3D G3DSA:1.10.260.30 310 443 3.8E-50 T 23-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 A0127_07770 5e0bfe5472087406cf31f1519c7e844b 448 Pfam PF02881 SRP54-type protein, helical bundle domain 6 83 4.3E-21 T 23-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A0127_07770 5e0bfe5472087406cf31f1519c7e844b 448 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 268 281 - T 23-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A0127_07770 5e0bfe5472087406cf31f1519c7e844b 448 SMART SM00962 100 295 2.7E-100 T 23-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A0127_07770 5e0bfe5472087406cf31f1519c7e844b 448 Pfam PF02978 Signal peptide binding domain 327 425 3.3E-34 T 23-10-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 A0127_07770 5e0bfe5472087406cf31f1519c7e844b 448 Pfam PF00448 SRP54-type protein, GTPase domain 100 295 2.6E-75 T 23-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A0127_07770 5e0bfe5472087406cf31f1519c7e844b 448 SUPERFAMILY SSF52540 96 297 7.09E-50 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_07770 5e0bfe5472087406cf31f1519c7e844b 448 Gene3D G3DSA:3.40.50.300 91 284 7.5E-124 T 23-10-2018 A0127_07770 5e0bfe5472087406cf31f1519c7e844b 448 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 6 438 38.657 T 23-10-2018 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 A0127_08510 2341491bf0a2d6c89150450a2ebef6f6 112 SUPERFAMILY SSF46950 8 111 1.7E-27 T 23-10-2018 IPR036883 PDCD5-like superfamily GO:0003677 A0127_08510 2341491bf0a2d6c89150450a2ebef6f6 112 Pfam PF01984 Double-stranded DNA-binding domain 8 111 9.8E-27 T 23-10-2018 IPR002836 PDCD5-like GO:0003677 A0127_08510 2341491bf0a2d6c89150450a2ebef6f6 112 Gene3D G3DSA:1.10.8.140 31 112 2.1E-26 T 23-10-2018 IPR036883 PDCD5-like superfamily GO:0003677 A0127_08510 2341491bf0a2d6c89150450a2ebef6f6 112 Hamap MF_00026 DNA-binding protein . 3 112 16.059 T 23-10-2018 IPR022889 DNA-binding protein, archaeal A0127_08510 2341491bf0a2d6c89150450a2ebef6f6 112 PIRSF PIRSF015730 1 112 1.6E-34 T 23-10-2018 IPR002836 PDCD5-like GO:0003677 A0127_09880 9745b1cdc3bbed9c0e28c9992c5c23a4 82 TIGRFAM TIGR01687 moaD_arch: MoaD family protein 1 82 2.0E-21 T 23-10-2018 IPR010038 MoaD, archaeal-type A0127_09880 9745b1cdc3bbed9c0e28c9992c5c23a4 82 Pfam PF02597 ThiS family 3 82 1.4E-21 T 23-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 A0127_09880 9745b1cdc3bbed9c0e28c9992c5c23a4 82 SUPERFAMILY SSF54285 2 82 1.09E-20 T 23-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp A0127_09880 9745b1cdc3bbed9c0e28c9992c5c23a4 82 Gene3D G3DSA:3.10.20.30 1 82 1.2E-23 T 23-10-2018 IPR012675 Beta-grasp domain superfamily A0127_08960 d98a60c72b53bdfa7c94ec17bd6322b5 95 Gene3D G3DSA:1.20.1270.90 5 85 1.5E-24 T 23-10-2018 A0127_08960 d98a60c72b53bdfa7c94ec17bd6322b5 95 Pfam PF04010 Protein of unknown function (DUF357) 12 84 1.5E-29 T 23-10-2018 IPR023140 Domain of unknown function DUF357 A0127_08960 d98a60c72b53bdfa7c94ec17bd6322b5 95 SUPERFAMILY SSF158372 5 85 1.15E-25 T 23-10-2018 IPR036809 AF1782-like superfamily A0127_04510 ae9bf0cda765fdcdb695accc8894a852 216 SUPERFAMILY SSF56300 20 156 2.53E-16 T 23-10-2018 A0127_04510 ae9bf0cda765fdcdb695accc8894a852 216 Gene3D G3DSA:3.60.21.10 20 133 4.4E-10 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like A0127_04510 ae9bf0cda765fdcdb695accc8894a852 216 PIRSF PIRSF000887 7 215 9.8E-38 T 23-10-2018 IPR024173 Phosphoesterase, MJ0037 A0127_04510 ae9bf0cda765fdcdb695accc8894a852 216 Pfam PF00149 Calcineurin-like phosphoesterase 20 129 1.4E-10 T 23-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 A0127_07700 85da33e0b22704839fafd0f3364b3a7f 57 ProSitePatterns PS01111 RNA polymerases K / 14 to 18 Kd subunits signature. 5 19 - T 23-10-2018 IPR020708 DNA-directed RNA polymerase, 14-18kDa subunit, conserved site GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A0127_07700 85da33e0b22704839fafd0f3364b3a7f 57 Hamap MF_00192 DNA-directed RNA polymerase subunit K [rpoK]. 2 57 21.829 T 23-10-2018 IPR006111 Archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A0127_07700 85da33e0b22704839fafd0f3364b3a7f 57 Pfam PF01192 RNA polymerase Rpb6 5 51 2.3E-11 T 23-10-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A0127_07700 85da33e0b22704839fafd0f3364b3a7f 57 PIRSF PIRSF000778 1 57 6.1E-23 T 23-10-2018 IPR006111 Archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A0127_07700 85da33e0b22704839fafd0f3364b3a7f 57 SUPERFAMILY SSF63562 3 55 9.29E-21 T 23-10-2018 IPR036161 RPB6/omega subunit-like superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A0127_07700 85da33e0b22704839fafd0f3364b3a7f 57 Gene3D G3DSA:3.90.940.50 1 57 8.7E-29 T 23-10-2018 A0127_09545 143c64be5da54cbda8851d94d46f4d12 316 SUPERFAMILY SSF101960 65 314 3.79E-47 T 23-10-2018 IPR037284 SUF system FeS cluster assembly, SufBD superfamily A0127_09545 143c64be5da54cbda8851d94d46f4d12 316 Pfam PF01458 Uncharacterized protein family (UPF0051) 95 312 4.7E-34 T 23-10-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 A0127_02755 30c72b82e913f7afd66c74bd4c437ec2 89 SUPERFAMILY SSF47598 12 48 1.78E-7 T 23-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 A0127_02755 30c72b82e913f7afd66c74bd4c437ec2 89 Pfam PF01402 Ribbon-helix-helix protein, copG family 12 42 9.6E-7 T 23-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 A0127_02755 30c72b82e913f7afd66c74bd4c437ec2 89 Gene3D G3DSA:1.10.1220.10 12 44 1.3E-6 T 23-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 A0127_03630 12f263f2a7bca490e53efebb475a3e7c 216 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 10 210 4.2E-68 T 23-10-2018 A0127_03630 12f263f2a7bca490e53efebb475a3e7c 216 Gene3D G3DSA:3.40.50.150 2 216 2.1E-95 T 23-10-2018 A0127_03630 12f263f2a7bca490e53efebb475a3e7c 216 Hamap MF_00090 Protein-L-isoaspartate O-methyltransferase [pcm]. 1 214 41.479 T 23-10-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 A0127_03630 12f263f2a7bca490e53efebb475a3e7c 216 TIGRFAM TIGR00080 pimt: protein-L-isoaspartate O-methyltransferase 8 211 2.3E-63 T 23-10-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 A0127_03630 12f263f2a7bca490e53efebb475a3e7c 216 ProSitePatterns PS01279 Protein-L-isoaspartate(D-aspartate) O-methyltransferase signature. 133 148 - T 23-10-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 A0127_03630 12f263f2a7bca490e53efebb475a3e7c 216 SUPERFAMILY SSF53335 2 212 6.66E-55 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A0127_00985 5020085d7014a66145cd62c2b726321b 58 Gene3D G3DSA:1.10.10.10 2 55 9.1E-13 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A0127_00985 5020085d7014a66145cd62c2b726321b 58 SUPERFAMILY SSF46785 4 55 2.57E-13 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A0127_00575 c9a26ff990d224fefce96712697d346e 396 Hamap MF_01893 tRNA pseudouridine synthase Pus10 [pus10]. 7 385 52.754 T 23-10-2018 IPR005912 tRNA pseudouridine synthase, Pus10 GO:0000049|GO:0001522|GO:0006400|GO:0009982 A0127_00575 c9a26ff990d224fefce96712697d346e 396 Pfam PF02926 THUMP domain 22 162 5.9E-11 T 23-10-2018 IPR004114 THUMP domain GO:0003723 A0127_00575 c9a26ff990d224fefce96712697d346e 396 TIGRFAM TIGR01213 pseudo_Pus10arc: tRNA pseudouridine(54/55) synthase 7 385 1.8E-148 T 23-10-2018 IPR005912 tRNA pseudouridine synthase, Pus10 GO:0000049|GO:0001522|GO:0006400|GO:0009982 A0127_00575 c9a26ff990d224fefce96712697d346e 396 Gene3D G3DSA:3.30.70.2510 162 275 3.1E-30 T 23-10-2018 A0127_00575 c9a26ff990d224fefce96712697d346e 396 SUPERFAMILY SSF55120 272 383 7.55E-12 T 23-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 A0127_00575 c9a26ff990d224fefce96712697d346e 396 Gene3D G3DSA:3.30.70.3190 276 384 2.1E-28 T 23-10-2018 A0127_02810 02dfd071e828ae7bfd560516100ec129 436 SUPERFAMILY SSF161070 16 402 5.75E-21 T 23-10-2018 IPR037272 Sodium:neurotransmitter symporter superfamily GO:0005328 A0127_02810 02dfd071e828ae7bfd560516100ec129 436 Pfam PF00209 Sodium:neurotransmitter symporter family 8 108 1.2E-4 T 23-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 A0127_08050 3d496cc93c56fc1054beee7b12e76f01 165 SUPERFAMILY SSF54747 3 82 6.15E-26 T 23-10-2018 IPR036796 Ribosomal protein L11/L12, N-terminal domain superfamily A0127_08050 3d496cc93c56fc1054beee7b12e76f01 165 SMART SM00649 5 138 2.0E-64 T 23-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 A0127_08050 3d496cc93c56fc1054beee7b12e76f01 165 Gene3D G3DSA:2.10.260.30 1 69 3.4E-28 T 23-10-2018 A0127_08050 3d496cc93c56fc1054beee7b12e76f01 165 Gene3D G3DSA:1.10.10.250 73 164 1.1E-36 T 23-10-2018 IPR036769 Ribosomal protein L11, C-terminal domain superfamily A0127_08050 3d496cc93c56fc1054beee7b12e76f01 165 Pfam PF00298 Ribosomal protein L11, RNA binding domain 71 137 2.6E-23 T 23-10-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 A0127_08050 3d496cc93c56fc1054beee7b12e76f01 165 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 1 139 28.497 T 23-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 A0127_08050 3d496cc93c56fc1054beee7b12e76f01 165 ProSitePatterns PS00359 Ribosomal protein L11 signature. 124 139 - T 23-10-2018 IPR020785 Ribosomal protein L11, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_08050 3d496cc93c56fc1054beee7b12e76f01 165 SUPERFAMILY SSF46906 66 138 1.44E-23 T 23-10-2018 IPR036769 Ribosomal protein L11, C-terminal domain superfamily A0127_08050 3d496cc93c56fc1054beee7b12e76f01 165 Pfam PF03946 Ribosomal protein L11, N-terminal domain 5 58 1.3E-22 T 23-10-2018 IPR020784 Ribosomal protein L11, N-terminal A0127_04610 0ccfc1ac2572af12015a8a160492b39f 442 Gene3D G3DSA:3.40.50.150 149 439 5.1E-91 T 23-10-2018 A0127_04610 0ccfc1ac2572af12015a8a160492b39f 442 Pfam PF17125 N-terminal domain of 16S rRNA methyltransferase RsmF 152 203 1.8E-9 T 23-10-2018 IPR031341 Ribosomal RNA small subunit methyltransferase F, N-terminal Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 A0127_04610 0ccfc1ac2572af12015a8a160492b39f 442 SUPERFAMILY SSF53335 144 440 1.67E-78 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A0127_04610 0ccfc1ac2572af12015a8a160492b39f 442 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 226 240 6.7E-24 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A0127_04610 0ccfc1ac2572af12015a8a160492b39f 442 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 422 439 6.7E-24 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A0127_04610 0ccfc1ac2572af12015a8a160492b39f 442 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 255 265 6.7E-24 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A0127_04610 0ccfc1ac2572af12015a8a160492b39f 442 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 323 335 6.7E-24 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A0127_04610 0ccfc1ac2572af12015a8a160492b39f 442 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 373 389 6.7E-24 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A0127_04610 0ccfc1ac2572af12015a8a160492b39f 442 TIGRFAM TIGR00446 nop2p: NOL1/NOP2/sun family putative RNA methylase 182 439 2.0E-64 T 23-10-2018 IPR011023 Nop2p GO:0003723|GO:0006364|GO:0008757 Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 A0127_04610 0ccfc1ac2572af12015a8a160492b39f 442 Pfam PF01189 16S rRNA methyltransferase RsmB/F 244 437 1.3E-63 T 23-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 A0127_04610 0ccfc1ac2572af12015a8a160492b39f 442 Gene3D G3DSA:1.10.940.10 1 148 2.6E-41 T 23-10-2018 IPR035926 NusB-like superfamily A0127_05580 549150387519975a9b97ae54b1b76c2e 226 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 8 212 1.3E-63 T 23-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A0127_05580 549150387519975a9b97ae54b1b76c2e 226 SUPERFAMILY SSF51351 3 219 4.45E-46 T 23-10-2018 IPR035990 Triosephosphate isomerase superfamily GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A0127_05580 549150387519975a9b97ae54b1b76c2e 226 Pfam PF00121 Triosephosphate isomerase 8 114 4.0E-10 T 23-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A0127_05580 549150387519975a9b97ae54b1b76c2e 226 Pfam PF05690 Thiazole biosynthesis protein ThiG 166 216 7.3E-6 T 23-10-2018 IPR033983 Thiazole synthase ThiG KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 A0127_05580 549150387519975a9b97ae54b1b76c2e 226 Hamap MF_00147_A Triosephosphate isomerase [tpiA]. 6 225 43.825 T 23-10-2018 IPR022891 Triosephosphate isomerase, archaeal GO:0004807|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003 A0127_05580 549150387519975a9b97ae54b1b76c2e 226 ProSitePatterns PS00171 Triosephosphate isomerase active site. 142 152 - T 23-10-2018 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A0127_05580 549150387519975a9b97ae54b1b76c2e 226 Gene3D G3DSA:3.20.20.70 1 225 1.5E-93 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A0127_05420 ac2cde8ad2f1b82cd4c5432d45a8c23d 430 Pfam PF03952 Enolase, N-terminal domain 7 135 2.7E-60 T 23-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A0127_05420 ac2cde8ad2f1b82cd4c5432d45a8c23d 430 Gene3D G3DSA:3.20.20.120 129 428 4.2E-134 T 23-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily A0127_05420 ac2cde8ad2f1b82cd4c5432d45a8c23d 430 SUPERFAMILY SSF54826 6 140 6.19E-58 T 23-10-2018 A0127_05420 ac2cde8ad2f1b82cd4c5432d45a8c23d 430 SUPERFAMILY SSF51604 139 428 5.11E-125 T 23-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily A0127_05420 ac2cde8ad2f1b82cd4c5432d45a8c23d 430 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 7 426 2.4E-198 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A0127_05420 ac2cde8ad2f1b82cd4c5432d45a8c23d 430 SMART SM01193 7 135 1.6E-95 T 23-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A0127_05420 ac2cde8ad2f1b82cd4c5432d45a8c23d 430 Hamap MF_00318 Enolase [eno]. 5 414 46.023 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A0127_05420 ac2cde8ad2f1b82cd4c5432d45a8c23d 430 SMART SM01192 140 428 1.9E-206 T 23-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A0127_05420 ac2cde8ad2f1b82cd4c5432d45a8c23d 430 PIRSF PIRSF001400 3 427 3.0E-196 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A0127_05420 ac2cde8ad2f1b82cd4c5432d45a8c23d 430 Gene3D G3DSA:3.30.390.10 2 128 1.1E-56 T 23-10-2018 IPR029017 Enolase-like, N-terminal A0127_05420 ac2cde8ad2f1b82cd4c5432d45a8c23d 430 Pfam PF00113 Enolase, C-terminal TIM barrel domain 141 427 7.5E-130 T 23-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A0127_05420 ac2cde8ad2f1b82cd4c5432d45a8c23d 430 PRINTS PR00148 Enolase signature 162 175 8.5E-50 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A0127_05420 ac2cde8ad2f1b82cd4c5432d45a8c23d 430 PRINTS PR00148 Enolase signature 108 124 8.5E-50 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A0127_05420 ac2cde8ad2f1b82cd4c5432d45a8c23d 430 PRINTS PR00148 Enolase signature 366 383 8.5E-50 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A0127_05420 ac2cde8ad2f1b82cd4c5432d45a8c23d 430 PRINTS PR00148 Enolase signature 337 351 8.5E-50 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A0127_05420 ac2cde8ad2f1b82cd4c5432d45a8c23d 430 PRINTS PR00148 Enolase signature 39 53 8.5E-50 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A0127_05420 ac2cde8ad2f1b82cd4c5432d45a8c23d 430 PRINTS PR00148 Enolase signature 314 325 8.5E-50 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A0127_05420 ac2cde8ad2f1b82cd4c5432d45a8c23d 430 ProSitePatterns PS00164 Enolase signature. 337 350 - T 23-10-2018 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A0127_02145 70bad1ccbf0a890152a07ccb50a92d7f 104 TIGRFAM TIGR01300 CPA3_mnhG_phaG: monovalent cation/proton antiporter, MnhG/PhaG subunit 6 99 9.5E-32 T 23-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 A0127_02145 70bad1ccbf0a890152a07ccb50a92d7f 104 Pfam PF03334 Na+/H+ antiporter subunit 6 86 3.1E-25 T 23-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 A0127_00690 e565258dfbc0e2c69bc7da56f92af7ee 136 SUPERFAMILY SSF50249 71 130 5.14E-13 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A0127_00690 e565258dfbc0e2c69bc7da56f92af7ee 136 TIGRFAM TIGR00037 eIF_5A: translation elongation factor IF5A 4 133 3.4E-48 T 23-10-2018 IPR001884 Translation elongation factor IF5A-like GO:0003723|GO:0003746|GO:0043022|GO:0045901 A0127_00690 e565258dfbc0e2c69bc7da56f92af7ee 136 Pfam PF01287 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold 70 134 3.7E-12 T 23-10-2018 IPR020189 Translation elongation factor, IF5A C-terminal GO:0003723|GO:0003746|GO:0006452|GO:0043022|GO:0045901|GO:0045905 A0127_00690 e565258dfbc0e2c69bc7da56f92af7ee 136 ProSitePatterns PS00302 Eukaryotic initiation factor 5A hypusine signature. 35 42 - T 23-10-2018 IPR019769 Translation elongation factor, IF5A, hypusine site GO:0003723|GO:0003746|GO:0043022|GO:0045901|GO:0045905 A0127_00690 e565258dfbc0e2c69bc7da56f92af7ee 136 PIRSF PIRSF003025 1 136 6.9E-45 T 23-10-2018 IPR001884 Translation elongation factor IF5A-like GO:0003723|GO:0003746|GO:0043022|GO:0045901 A0127_00690 e565258dfbc0e2c69bc7da56f92af7ee 136 SUPERFAMILY SSF50104 5 78 1.05E-20 T 23-10-2018 IPR008991 Translation protein SH3-like domain superfamily A0127_00690 e565258dfbc0e2c69bc7da56f92af7ee 136 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 9 40 5.9E-5 T 23-10-2018 IPR013185 Translation elongation factor, KOW-like A0127_00690 e565258dfbc0e2c69bc7da56f92af7ee 136 SMART SM01376 70 134 2.3E-18 T 23-10-2018 IPR020189 Translation elongation factor, IF5A C-terminal GO:0003723|GO:0003746|GO:0006452|GO:0043022|GO:0045901|GO:0045905 A0127_00690 e565258dfbc0e2c69bc7da56f92af7ee 136 Hamap MF_00085 Translation initiation factor 5A [eif5a]. 3 133 34.538 T 23-10-2018 IPR022847 Translation elongation factor IF5A, archaeal A0127_00690 e565258dfbc0e2c69bc7da56f92af7ee 136 Gene3D G3DSA:2.40.50.140 71 135 2.4E-29 T 23-10-2018 A0127_00690 e565258dfbc0e2c69bc7da56f92af7ee 136 Gene3D G3DSA:2.30.30.30 1 70 1.4E-28 T 23-10-2018 IPR014722 Ribosomal protein L2, domain 2 A0127_06625 ed5ccc27b8861c7eccb2c0570cd07932 240 Gene3D G3DSA:3.40.720.10 49 228 9.2E-6 T 23-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 A0127_06625 ed5ccc27b8861c7eccb2c0570cd07932 240 SUPERFAMILY SSF53649 37 199 1.0E-5 T 23-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 A0127_06625 ed5ccc27b8861c7eccb2c0570cd07932 240 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 33 202 5.4E-5 T 23-10-2018 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 A0127_01935 6da7b1b5cb827807b49a844a0906b123 198 Pfam PF04013 Putative SAM-dependent RNA methyltransferase 1 196 1.3E-52 T 23-10-2018 IPR007158 tRNA (pseudouridine(54)-N(1))-methyltransferase, TrmY GO:0008175 A0127_01935 6da7b1b5cb827807b49a844a0906b123 198 SUPERFAMILY SSF75217 1 196 1.44E-66 T 23-10-2018 IPR029028 Alpha/beta knot methyltransferases A0127_01935 6da7b1b5cb827807b49a844a0906b123 198 Hamap MF_00587 tRNA (pseudouridine(54)-N(1))-methyltransferase [trmY]. 1 197 36.176 T 23-10-2018 IPR007158 tRNA (pseudouridine(54)-N(1))-methyltransferase, TrmY GO:0008175 A0127_01935 6da7b1b5cb827807b49a844a0906b123 198 Gene3D G3DSA:3.40.1280.10 1 198 1.4E-71 T 23-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal A0127_09275 a95b84a77de3be1634de008cb1787689 170 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 9 166 1.3E-37 T 23-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 A0127_09275 a95b84a77de3be1634de008cb1787689 170 SUPERFAMILY SSF53323 2 168 4.71E-41 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 A0127_09275 a95b84a77de3be1634de008cb1787689 170 Gene3D G3DSA:3.40.920.10 1 170 1.7E-53 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 A0127_08965 40d0c7b59eb0cb0dd1cbacbf8d42d36f 131 ProDom PD020367 UPF0212 RRNAC1165 RRNAC0441 AF0282 VNG1264C MJ0068 PYRAB08340 PH1312 MA1372 TK1194 1 91 3.0E-47 T 23-10-2018 IPR007564 Uncharacterised protein family UPF0212 A0127_08965 40d0c7b59eb0cb0dd1cbacbf8d42d36f 131 Hamap MF_01223 UPF0212 protein . 1 112 32.362 T 23-10-2018 IPR007564 Uncharacterised protein family UPF0212 A0127_08965 40d0c7b59eb0cb0dd1cbacbf8d42d36f 131 PIRSF PIRSF016934 1 125 4.8E-54 T 23-10-2018 IPR007564 Uncharacterised protein family UPF0212 A0127_08965 40d0c7b59eb0cb0dd1cbacbf8d42d36f 131 Pfam PF04475 Protein of unknown function (DUF555) 3 104 3.2E-40 T 23-10-2018 IPR007564 Uncharacterised protein family UPF0212 A0127_01020 3c1f4934fb73d711231ac23384980733 409 PIRSF PIRSF005243 4 409 7.0E-115 T 23-10-2018 IPR016440 Rubredoxin-oxygen oxidoreductase GO:0009055|GO:0010181|GO:0016491|GO:0046872 A0127_01020 3c1f4934fb73d711231ac23384980733 409 SUPERFAMILY SSF52218 262 408 1.9E-30 T 23-10-2018 IPR029039 Flavoprotein-like superfamily A0127_01020 3c1f4934fb73d711231ac23384980733 409 Pfam PF00753 Metallo-beta-lactamase superfamily 41 185 2.4E-6 T 23-10-2018 IPR001279 Metallo-beta-lactamase A0127_01020 3c1f4934fb73d711231ac23384980733 409 Gene3D G3DSA:3.40.50.360 259 407 2.1E-29 T 23-10-2018 IPR029039 Flavoprotein-like superfamily A0127_01020 3c1f4934fb73d711231ac23384980733 409 SUPERFAMILY SSF56281 15 255 2.23E-44 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A0127_01020 3c1f4934fb73d711231ac23384980733 409 Gene3D G3DSA:3.60.15.10 1 258 1.0E-88 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A0127_01020 3c1f4934fb73d711231ac23384980733 409 SMART SM00849 39 209 9.2E-28 T 23-10-2018 IPR001279 Metallo-beta-lactamase A0127_09835 3cc1376cbcbf09b3de81ccdb36f25b53 147 Pfam PF00164 Ribosomal protein S12/S23 32 146 4.8E-51 T 23-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A0127_09835 3cc1376cbcbf09b3de81ccdb36f25b53 147 SUPERFAMILY SSF50249 23 147 5.65E-37 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A0127_09835 3cc1376cbcbf09b3de81ccdb36f25b53 147 Hamap MF_00403_A 30S ribosomal protein S12 [rpsL]. 1 147 45.317 T 23-10-2018 IPR022863 Ribosomal protein S12, archaea A0127_09835 3cc1376cbcbf09b3de81ccdb36f25b53 147 TIGRFAM TIGR00982 uS12_E_A: ribosomal protein uS12 9 147 2.7E-82 T 23-10-2018 IPR005680 Ribosomal protein S23, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_09835 3cc1376cbcbf09b3de81ccdb36f25b53 147 PIRSF PIRSF002133 19 147 3.4E-37 T 23-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A0127_09835 3cc1376cbcbf09b3de81ccdb36f25b53 147 PRINTS PR01034 Ribosomal protein S12 signature 47 62 4.6E-5 T 23-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A0127_09835 3cc1376cbcbf09b3de81ccdb36f25b53 147 PRINTS PR01034 Ribosomal protein S12 signature 79 98 4.6E-5 T 23-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A0127_09835 3cc1376cbcbf09b3de81ccdb36f25b53 147 PRINTS PR01034 Ribosomal protein S12 signature 62 77 4.6E-5 T 23-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A0127_09835 3cc1376cbcbf09b3de81ccdb36f25b53 147 ProSitePatterns PS00055 Ribosomal protein S12 signature. 63 70 - T 23-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A0127_09835 3cc1376cbcbf09b3de81ccdb36f25b53 147 Gene3D G3DSA:2.40.50.140 28 147 2.3E-51 T 23-10-2018 A0127_03485 47255f4d725fbda96e9a0aed7384dee8 326 ProSitePatterns PS00211 ABC transporters family signature. 162 176 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A0127_03485 47255f4d725fbda96e9a0aed7384dee8 326 SUPERFAMILY SSF52540 34 323 4.33E-67 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_03485 47255f4d725fbda96e9a0aed7384dee8 326 Gene3D G3DSA:3.40.50.300 3 326 3.0E-97 T 23-10-2018 A0127_03485 47255f4d725fbda96e9a0aed7384dee8 326 Pfam PF00005 ABC transporter 26 189 4.3E-25 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A0127_03485 47255f4d725fbda96e9a0aed7384dee8 326 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 241 305 1.1E-20 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A0127_03485 47255f4d725fbda96e9a0aed7384dee8 326 SMART SM00382 34 247 2.5E-12 T 23-10-2018 IPR003593 AAA+ ATPase domain A0127_03485 47255f4d725fbda96e9a0aed7384dee8 326 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 239 325 3.8E-32 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A0127_06520 fa2d46363853966da62884058c77e06f 456 Pfam PF00884 Sulfatase 4 325 1.9E-18 T 23-10-2018 IPR000917 Sulfatase, N-terminal GO:0008484 A0127_06520 fa2d46363853966da62884058c77e06f 456 SUPERFAMILY SSF53649 4 441 1.37E-38 T 23-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 A0127_06520 fa2d46363853966da62884058c77e06f 456 Gene3D G3DSA:3.40.720.10 1 168 9.4E-16 T 23-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 A0127_06520 fa2d46363853966da62884058c77e06f 456 Gene3D G3DSA:3.40.720.10 171 355 1.2E-29 T 23-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 A0127_09925 af95c7027b7f1c3c8984a3cdb5f77427 158 SUPERFAMILY SSF47240 1 146 1.83E-29 T 23-10-2018 IPR009078 Ferritin-like superfamily A0127_09925 af95c7027b7f1c3c8984a3cdb5f77427 158 Gene3D G3DSA:1.20.1260.10 1 142 7.5E-27 T 23-10-2018 IPR012347 Ferritin-like A0127_09925 af95c7027b7f1c3c8984a3cdb5f77427 158 Pfam PF02915 Rubrerythrin 5 137 3.3E-15 T 23-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 A0127_01445 5102d2d284f84de3e0424c4e9f5bb89f 179 Pfam PF10007 Uncharacterized protein conserved in archaea (DUF2250) 16 106 1.2E-33 T 23-10-2018 IPR019254 Protein of unknown function DUF2250 A0127_01445 5102d2d284f84de3e0424c4e9f5bb89f 179 PIRSF PIRSF037213 4 178 1.0E-63 T 23-10-2018 IPR017139 Uncharacterised conserved protein UCP037213 A0127_01245 1acfb571c27332ab08a367f3d61e88c0 334 SMART SM00846 3 141 3.3E-28 T 23-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A0127_01245 1acfb571c27332ab08a367f3d61e88c0 334 TIGRFAM TIGR01546 GAPDH-II_archae: glyceraldehyde-3-phosphate dehydrogenase, type II 5 333 1.3E-180 T 23-10-2018 IPR006436 Glyceraldehyde-3-phosphate dehydrogenase, type II GO:0005737|GO:0006096|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.59|KEGG: 00710+1.2.1.59 A0127_01245 1acfb571c27332ab08a367f3d61e88c0 334 SUPERFAMILY SSF51735 3 158 2.29E-48 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A0127_01245 1acfb571c27332ab08a367f3d61e88c0 334 Gene3D G3DSA:3.30.360.10 140 301 1.5E-150 T 23-10-2018 A0127_01245 1acfb571c27332ab08a367f3d61e88c0 334 SUPERFAMILY SSF55347 140 301 3.03E-53 T 23-10-2018 A0127_01245 1acfb571c27332ab08a367f3d61e88c0 334 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 139 146 - T 23-10-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A0127_01245 1acfb571c27332ab08a367f3d61e88c0 334 PIRSF PIRSF000149 1 318 4.7E-87 T 23-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A0127_01245 1acfb571c27332ab08a367f3d61e88c0 334 Hamap MF_00559 Glyceraldehyde-3-phosphate dehydrogenase [gap]. 1 334 191.12 T 23-10-2018 IPR006436 Glyceraldehyde-3-phosphate dehydrogenase, type II GO:0005737|GO:0006096|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.59|KEGG: 00710+1.2.1.59 A0127_01245 1acfb571c27332ab08a367f3d61e88c0 334 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 3 118 2.2E-13 T 23-10-2018 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A0127_01245 1acfb571c27332ab08a367f3d61e88c0 334 Gene3D G3DSA:3.40.50.720 3 331 1.5E-150 T 23-10-2018 A0127_01245 1acfb571c27332ab08a367f3d61e88c0 334 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 146 296 1.5E-31 T 23-10-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 A0127_09900 91b07880da6cd4aae701ea5a5b458bef 270 SUPERFAMILY SSF82861 16 100 1.44E-10 T 23-10-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 A0127_09900 91b07880da6cd4aae701ea5a5b458bef 270 Gene3D G3DSA:3.30.70.100 167 261 4.1E-31 T 23-10-2018 A0127_09900 91b07880da6cd4aae701ea5a5b458bef 270 SUPERFAMILY SSF82689 168 266 5.75E-33 T 23-10-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 A0127_09900 91b07880da6cd4aae701ea5a5b458bef 270 SUPERFAMILY SSF50182 101 167 4.9E-15 T 23-10-2018 IPR010920 LSM domain superfamily A0127_09900 91b07880da6cd4aae701ea5a5b458bef 270 Pfam PF00924 Mechanosensitive ion channel 60 256 1.0E-48 T 23-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 A0127_09900 91b07880da6cd4aae701ea5a5b458bef 270 Pfam PF05552 Conserved TM helix 17 48 1.5E-6 T 23-10-2018 IPR008910 Conserved TM helix A0127_09900 91b07880da6cd4aae701ea5a5b458bef 270 Gene3D G3DSA:2.30.30.60 117 166 8.9E-16 T 23-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily A0127_05340 8b1aee32516556cfa025d3a1a56d7c4a 176 Gene3D G3DSA:3.40.50.12280 9 176 8.6E-53 T 23-10-2018 A0127_05340 8b1aee32516556cfa025d3a1a56d7c4a 176 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 47 156 3.2E-28 T 23-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A0127_05340 8b1aee32516556cfa025d3a1a56d7c4a 176 SUPERFAMILY SSF56770 34 165 1.44E-53 T 23-10-2018 A0127_09890 0b5e31a0134ed988321e75df52d13b36 123 Gene3D G3DSA:1.10.3730.20 13 123 1.8E-9 T 23-10-2018 A0127_09890 0b5e31a0134ed988321e75df52d13b36 123 SUPERFAMILY SSF103481 46 121 5.89E-15 T 23-10-2018 A0127_09890 0b5e31a0134ed988321e75df52d13b36 123 Pfam PF00892 EamA-like transporter family 48 119 4.5E-11 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A0127_00180 5c2ae405fa8f113950d17f1466a6cf5d 232 Pfam PF03099 Biotin/lipoate A/B protein ligase family 11 122 6.5E-21 T 23-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 A0127_00180 5c2ae405fa8f113950d17f1466a6cf5d 232 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 7 228 2.2E-55 T 23-10-2018 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A0127_00180 5c2ae405fa8f113950d17f1466a6cf5d 232 Pfam PF02237 Biotin protein ligase C terminal domain 184 229 1.5E-7 T 23-10-2018 IPR003142 Biotin protein ligase, C-terminal GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A0127_00180 5c2ae405fa8f113950d17f1466a6cf5d 232 SUPERFAMILY SSF50037 184 229 1.92E-7 T 23-10-2018 IPR008988 Transcriptional repressor, C-terminal A0127_00180 5c2ae405fa8f113950d17f1466a6cf5d 232 Gene3D G3DSA:3.30.930.10 3 181 2.5E-56 T 23-10-2018 A0127_00180 5c2ae405fa8f113950d17f1466a6cf5d 232 Gene3D G3DSA:2.30.30.100 183 232 5.6E-9 T 23-10-2018 A0127_00180 5c2ae405fa8f113950d17f1466a6cf5d 232 SUPERFAMILY SSF55681 2 171 2.42E-51 T 23-10-2018 A0127_09825 55c9174fad90e30603ec5bfa763cc92e 102 Pfam PF01248 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family 7 95 9.2E-20 T 23-10-2018 IPR004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45 A0127_09825 55c9174fad90e30603ec5bfa763cc92e 102 Hamap MF_00481 50S ribosomal protein L30e [rpl30e]. 2 99 29.776 T 23-10-2018 IPR000231 Ribosomal protein L30e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_09825 55c9174fad90e30603ec5bfa763cc92e 102 SUPERFAMILY SSF55315 3 97 4.53E-27 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like A0127_09825 55c9174fad90e30603ec5bfa763cc92e 102 ProSitePatterns PS00993 Ribosomal protein L30e signature 2. 70 90 - T 23-10-2018 IPR022991 Ribosomal protein L30e, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_09825 55c9174fad90e30603ec5bfa763cc92e 102 Gene3D G3DSA:3.30.1330.30 1 101 1.0E-38 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like A0127_03845 85d9843c820b4e5b7a98b41e6330a5ba 450 Gene3D G3DSA:1.10.940.10 6 150 8.9E-16 T 23-10-2018 IPR035926 NusB-like superfamily A0127_03845 85d9843c820b4e5b7a98b41e6330a5ba 450 SUPERFAMILY SSF53335 147 450 2.17E-70 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A0127_03845 85d9843c820b4e5b7a98b41e6330a5ba 450 Gene3D G3DSA:3.40.50.150 154 450 2.2E-76 T 23-10-2018 A0127_03845 85d9843c820b4e5b7a98b41e6330a5ba 450 Pfam PF01029 NusB family 10 133 2.3E-20 T 23-10-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 A0127_03845 85d9843c820b4e5b7a98b41e6330a5ba 450 Pfam PF01189 16S rRNA methyltransferase RsmB/F 255 448 3.2E-48 T 23-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 A0127_03845 85d9843c820b4e5b7a98b41e6330a5ba 450 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 381 397 4.1E-21 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A0127_03845 85d9843c820b4e5b7a98b41e6330a5ba 450 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 266 276 4.1E-21 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A0127_03845 85d9843c820b4e5b7a98b41e6330a5ba 450 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 331 343 4.1E-21 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A0127_03845 85d9843c820b4e5b7a98b41e6330a5ba 450 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 433 450 4.1E-21 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A0127_03845 85d9843c820b4e5b7a98b41e6330a5ba 450 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 237 251 4.1E-21 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A0127_03845 85d9843c820b4e5b7a98b41e6330a5ba 450 SUPERFAMILY SSF48013 9 163 2.88E-25 T 23-10-2018 IPR035926 NusB-like superfamily A0127_10055 0ba98b252f55cf986b2cc3e892de721e 330 SUPERFAMILY SSF56042 145 313 1.79E-35 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A0127_10055 0ba98b252f55cf986b2cc3e892de721e 330 Pfam PF02769 AIR synthase related protein, C-terminal domain 151 308 4.0E-26 T 23-10-2018 IPR010918 PurM-like, C-terminal domain A0127_10055 0ba98b252f55cf986b2cc3e892de721e 330 Pfam PF00586 AIR synthase related protein, N-terminal domain 41 139 4.8E-16 T 23-10-2018 IPR016188 PurM-like, N-terminal domain A0127_10055 0ba98b252f55cf986b2cc3e892de721e 330 PIRSF PIRSF005644 5 328 1.8E-88 T 23-10-2018 IPR011854 Carbamoyl dehydratase HypE A0127_10055 0ba98b252f55cf986b2cc3e892de721e 330 Gene3D G3DSA:3.30.1330.10 7 142 3.1E-29 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A0127_10055 0ba98b252f55cf986b2cc3e892de721e 330 Gene3D G3DSA:3.90.650.10 144 327 7.7E-49 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A0127_10055 0ba98b252f55cf986b2cc3e892de721e 330 SUPERFAMILY SSF55326 6 143 3.84E-25 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A0127_05405 e983ef44a4c8d46ab7e5b79978fcf9be 94 ProDom PD029791 ORF 3'REGION GAP PF1875 PF0899 PH1831 B PHS036 19 76 9.0E-27 T 23-10-2018 IPR014418 Uncharacterised conserved protein UCP004604 A0127_05405 e983ef44a4c8d46ab7e5b79978fcf9be 94 Pfam PF08967 Domain of unknown function (DUF1884) 1 78 4.0E-32 T 23-10-2018 IPR014418 Uncharacterised conserved protein UCP004604 A0127_05405 e983ef44a4c8d46ab7e5b79978fcf9be 94 Gene3D G3DSA:3.30.2320.10 1 77 3.2E-24 T 23-10-2018 A0127_05405 e983ef44a4c8d46ab7e5b79978fcf9be 94 PIRSF PIRSF004604 1 93 1.0E-31 T 23-10-2018 IPR014418 Uncharacterised conserved protein UCP004604 A0127_05405 e983ef44a4c8d46ab7e5b79978fcf9be 94 SUPERFAMILY SSF111057 1 76 7.59E-29 T 23-10-2018 IPR036216 Hypothetical protein UCP004604 superfamily A0127_00700 a66b902f71d167c196ec04dbad27d8dd 220 Pfam PF03587 EMG1/NEP1 methyltransferase 5 215 2.7E-51 T 23-10-2018 IPR005304 Ribosomal biogenesis, methyltransferase, EMG1/NEP1 GO:0008168 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 A0127_00700 a66b902f71d167c196ec04dbad27d8dd 220 SUPERFAMILY SSF75217 1 219 2.62E-63 T 23-10-2018 IPR029028 Alpha/beta knot methyltransferases A0127_00700 a66b902f71d167c196ec04dbad27d8dd 220 Hamap MF_00554 Ribosomal RNA small subunit methyltransferase Nep1 [nep1]. 2 216 40.164 T 23-10-2018 IPR023503 Ribosome biogenesis methyltransferase NEP1, archaea GO:0008168 A0127_00700 a66b902f71d167c196ec04dbad27d8dd 220 Gene3D G3DSA:3.40.1280.10 1 219 2.8E-76 T 23-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal A0127_04080 8c45061e8c2d24a7265614c96d18c9d2 259 Pfam PF01435 Peptidase family M48 55 248 3.5E-22 T 23-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 A0127_04080 8c45061e8c2d24a7265614c96d18c9d2 259 Gene3D G3DSA:3.30.2010.10 49 132 8.2E-18 T 23-10-2018 A0127_07665 45e5161e70d3b3fd94f750bb2e9e3467 261 Gene3D G3DSA:2.170.120.12 41 148 8.0E-99 T 23-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A0127_07665 45e5161e70d3b3fd94f750bb2e9e3467 261 Gene3D G3DSA:3.30.70.3110 158 219 8.0E-99 T 23-10-2018 A0127_07665 45e5161e70d3b3fd94f750bb2e9e3467 261 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 17 248 8.3E-19 T 23-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A0127_07665 45e5161e70d3b3fd94f750bb2e9e3467 261 SUPERFAMILY SSF55257 4 258 5.65E-29 T 23-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A0127_07665 45e5161e70d3b3fd94f750bb2e9e3467 261 SUPERFAMILY SSF56553 40 150 1.31E-28 T 23-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A0127_07665 45e5161e70d3b3fd94f750bb2e9e3467 261 Gene3D G3DSA:3.30.1360.10 7 252 8.0E-99 T 23-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A0127_07665 45e5161e70d3b3fd94f750bb2e9e3467 261 SMART SM00662 15 255 3.9E-83 T 23-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A0127_07665 45e5161e70d3b3fd94f750bb2e9e3467 261 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 47 149 1.2E-27 T 23-10-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A0127_07665 45e5161e70d3b3fd94f750bb2e9e3467 261 Hamap MF_00320 DNA-directed RNA polymerase subunit D [rpoD]. 4 258 32.949 T 23-10-2018 IPR022842 DNA-directed RNA polymerase subunit D (Rpo3) GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A0127_07665 45e5161e70d3b3fd94f750bb2e9e3467 261 ProSitePatterns PS00446 RNA polymerases D / 30 to 40 Kd subunits signature. 29 69 - T 23-10-2018 IPR001514 DNA-directed RNA polymerase, 30-40kDa subunit, conserved site GO:0003677|GO:0003899|GO:0006351 A0127_00045 5663259c42117ac73c634d8f82af2877 810 SMART SM00278 747 766 850.0 T 23-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A0127_00045 5663259c42117ac73c634d8f82af2877 810 SMART SM00278 779 798 0.021 T 23-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A0127_00045 5663259c42117ac73c634d8f82af2877 810 SMART SM00490 373 462 2.8E-25 T 23-10-2018 IPR001650 Helicase, C-terminal A0127_00045 5663259c42117ac73c634d8f82af2877 810 Pfam PF02732 ERCC4 domain 599 717 2.2E-29 T 23-10-2018 IPR006166 ERCC4 domain GO:0003677|GO:0004518 Reactome: R-HSA-6783310 A0127_00045 5663259c42117ac73c634d8f82af2877 810 SUPERFAMILY SSF47781 734 803 5.19E-16 T 23-10-2018 IPR010994 RuvA domain 2-like A0127_00045 5663259c42117ac73c634d8f82af2877 810 SMART SM00487 7 202 1.6E-31 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A0127_00045 5663259c42117ac73c634d8f82af2877 810 Pfam PF00270 DEAD/DEAH box helicase 15 170 5.3E-20 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A0127_00045 5663259c42117ac73c634d8f82af2877 810 Gene3D G3DSA:3.40.50.300 3 200 2.6E-73 T 23-10-2018 A0127_00045 5663259c42117ac73c634d8f82af2877 810 SMART SM00891 596 676 4.4E-32 T 23-10-2018 IPR006166 ERCC4 domain GO:0003677|GO:0004518 Reactome: R-HSA-6783310 A0127_00045 5663259c42117ac73c634d8f82af2877 810 Pfam PF00271 Helicase conserved C-terminal domain 344 461 1.0E-23 T 23-10-2018 IPR001650 Helicase, C-terminal A0127_00045 5663259c42117ac73c634d8f82af2877 810 Gene3D G3DSA:1.20.1320.20 213 339 2.3E-100 T 23-10-2018 A0127_00045 5663259c42117ac73c634d8f82af2877 810 Gene3D G3DSA:3.40.50.10130 592 733 1.9E-53 T 23-10-2018 A0127_00045 5663259c42117ac73c634d8f82af2877 810 Pfam PF12826 Helix-hairpin-helix motif 751 802 5.9E-10 T 23-10-2018 A0127_00045 5663259c42117ac73c634d8f82af2877 810 Gene3D G3DSA:1.10.150.20 734 808 2.5E-23 T 23-10-2018 A0127_00045 5663259c42117ac73c634d8f82af2877 810 Gene3D G3DSA:3.40.50.300 210 479 2.3E-100 T 23-10-2018 A0127_00045 5663259c42117ac73c634d8f82af2877 810 SUPERFAMILY SSF52540 53 481 5.95E-61 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_00045 5663259c42117ac73c634d8f82af2877 810 SUPERFAMILY SSF52980 595 724 3.75E-38 T 23-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 A0127_09385 6e0238f7290e4bdc7164f75c3a953769 149 Pfam PF03334 Na+/H+ antiporter subunit 14 100 8.9E-15 T 23-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 A0127_09385 6e0238f7290e4bdc7164f75c3a953769 149 TIGRFAM TIGR01300 CPA3_mnhG_phaG: monovalent cation/proton antiporter, MnhG/PhaG subunit 13 114 5.7E-19 T 23-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 A0127_09060 fa12aa727e7f11a85913ee3a78fb6d10 128 SUPERFAMILY SSF52980 3 113 8.58E-30 T 23-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 A0127_09060 fa12aa727e7f11a85913ee3a78fb6d10 128 Pfam PF01870 Archaeal holliday junction resolvase (hjc) 9 94 4.1E-28 T 23-10-2018 IPR002732 Holliday junction resolvase Hjc A0127_09060 fa12aa727e7f11a85913ee3a78fb6d10 128 Gene3D G3DSA:3.40.1350.10 2 128 6.8E-38 T 23-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 A0127_09060 fa12aa727e7f11a85913ee3a78fb6d10 128 PIRSF PIRSF004985 1 121 1.6E-38 T 23-10-2018 IPR014428 Holliday junction resolvase Hjc, archaeal A0127_09060 fa12aa727e7f11a85913ee3a78fb6d10 128 Hamap MF_01490 Holliday junction resolvase Hjc [hjc]. 2 124 38.2 T 23-10-2018 IPR014428 Holliday junction resolvase Hjc, archaeal A0127_09060 fa12aa727e7f11a85913ee3a78fb6d10 128 ProDom PD015874 RESOLVASE HOLLIDAY JUNCTION ARCHAEAL HOLLIDAY-JUNCTION TYPE MJ0497 ORF-C21_024 PF1503 NEQ424 10 90 6.0E-40 T 23-10-2018 IPR014428 Holliday junction resolvase Hjc, archaeal A0127_01005 27422f75032fef3c01690ea267b0030c 152 SUPERFAMILY SSF52833 2 148 4.92E-46 T 23-10-2018 IPR036249 Thioredoxin-like superfamily A0127_01005 27422f75032fef3c01690ea267b0030c 152 Pfam PF00578 AhpC/TSA family 3 127 4.5E-35 T 23-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A0127_01005 27422f75032fef3c01690ea267b0030c 152 Gene3D G3DSA:3.40.30.10 1 147 3.1E-47 T 23-10-2018 A0127_01005 27422f75032fef3c01690ea267b0030c 152 PIRSF PIRSF000239 1 147 6.5E-24 T 23-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A0127_07110 c21176fd98dbafbc5620c26e48d7d4bf 164 Gene3D G3DSA:1.20.58.2050 1 164 2.2E-93 T 23-10-2018 IPR038437 GINS complex, subunit Psf3 superfamily Reactome: R-HSA-176974 A0127_07110 c21176fd98dbafbc5620c26e48d7d4bf 164 Pfam PF05916 GINS complex protein 28 147 2.1E-9 T 23-10-2018 IPR021151 GINS subunit, domain A Reactome: R-HSA-176974 A0127_03225 5f66a43619ddc50fd20c1aa2a25a6d83 264 Gene3D G3DSA:3.30.950.10 115 264 2.7E-54 T 23-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 A0127_03225 5f66a43619ddc50fd20c1aa2a25a6d83 264 TIGRFAM TIGR00522 dph5: diphthine synthase 3 256 1.9E-107 T 23-10-2018 IPR004551 Diphthine synthase GO:0004164|GO:0017183 Reactome: R-HSA-5358493 A0127_03225 5f66a43619ddc50fd20c1aa2a25a6d83 264 Gene3D G3DSA:3.40.1010.10 1 114 1.2E-41 T 23-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 A0127_03225 5f66a43619ddc50fd20c1aa2a25a6d83 264 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 3 212 3.2E-21 T 23-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 A0127_03225 5f66a43619ddc50fd20c1aa2a25a6d83 264 Hamap MF_01084 Diphthine synthase [dphB]. 2 256 36.974 T 23-10-2018 IPR004551 Diphthine synthase GO:0004164|GO:0017183 Reactome: R-HSA-5358493 A0127_03225 5f66a43619ddc50fd20c1aa2a25a6d83 264 SUPERFAMILY SSF53790 1 259 5.23E-64 T 23-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 A0127_03225 5f66a43619ddc50fd20c1aa2a25a6d83 264 PIRSF PIRSF036432 2 260 1.3E-101 T 23-10-2018 IPR004551 Diphthine synthase GO:0004164|GO:0017183 Reactome: R-HSA-5358493 A0127_00780 fac6a80f0591a3acd8243e4a0f9dd54e 747 Gene3D G3DSA:1.10.287.950 442 746 2.1E-64 T 23-10-2018 A0127_00780 fac6a80f0591a3acd8243e4a0f9dd54e 747 SUPERFAMILY SSF58104 410 745 3.92E-62 T 23-10-2018 A0127_00780 fac6a80f0591a3acd8243e4a0f9dd54e 747 Gene3D G3DSA:3.30.450.20 122 200 5.8E-42 T 23-10-2018 A0127_00780 fac6a80f0591a3acd8243e4a0f9dd54e 747 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 569 596 4.1E-22 T 23-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 A0127_00780 fac6a80f0591a3acd8243e4a0f9dd54e 747 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 492 521 4.1E-22 T 23-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 A0127_00780 fac6a80f0591a3acd8243e4a0f9dd54e 747 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 598 627 4.1E-22 T 23-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 A0127_00780 fac6a80f0591a3acd8243e4a0f9dd54e 747 Gene3D G3DSA:3.30.450.20 201 293 5.8E-42 T 23-10-2018 A0127_00780 fac6a80f0591a3acd8243e4a0f9dd54e 747 SMART SM00283 471 746 2.1E-64 T 23-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 A0127_00780 fac6a80f0591a3acd8243e4a0f9dd54e 747 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 533 668 5.0E-37 T 23-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 A0127_00780 fac6a80f0591a3acd8243e4a0f9dd54e 747 SUPERFAMILY SSF103190 115 209 1.47E-16 T 23-10-2018 IPR029151 Periplasmic sensor-like domain superfamily A0127_00780 fac6a80f0591a3acd8243e4a0f9dd54e 747 Pfam PF02743 Cache domain 46 290 5.0E-41 T 23-10-2018 IPR033479 Double Cache domain 1 A0127_09615 dfae78df03b1cd312c245525086d02cc 581 Gene3D G3DSA:1.10.599.10 386 579 2.1E-33 T 23-10-2018 IPR013985 Aldehyde ferredoxin oxidoreductase, domain 3 GO:0016625|GO:0051536|GO:0055114 KEGG: 00030+1.2.7.5 A0127_09615 dfae78df03b1cd312c245525086d02cc 581 Gene3D G3DSA:1.10.569.10 241 385 1.3E-21 T 23-10-2018 IPR013984 Aldehyde ferredoxin oxidoreductase, domain 2 A0127_09615 dfae78df03b1cd312c245525086d02cc 581 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 6 192 1.8E-62 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 A0127_09615 dfae78df03b1cd312c245525086d02cc 581 SUPERFAMILY SSF48310 198 579 1.44E-77 T 23-10-2018 IPR036021 Aldehyde ferredoxin oxidoreductase-like, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 A0127_09615 dfae78df03b1cd312c245525086d02cc 581 SMART SM00790 4 193 1.0E-99 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 A0127_09615 dfae78df03b1cd312c245525086d02cc 581 Gene3D G3DSA:3.60.9.10 1 196 1.3E-64 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily A0127_09615 dfae78df03b1cd312c245525086d02cc 581 SUPERFAMILY SSF56228 1 194 2.88E-59 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily A0127_09615 dfae78df03b1cd312c245525086d02cc 581 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 247 577 2.9E-55 T 23-10-2018 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 A0127_07565 147c9eaffa76a8382e467af3e4a12500 148 ProSitePatterns PS00526 Ribosomal protein L19e signature. 5 24 - T 23-10-2018 IPR023638 Ribosomal protein L19/L19e conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_07565 147c9eaffa76a8382e467af3e4a12500 148 SMART SM01416 1 144 2.3E-87 T 23-10-2018 IPR000196 Ribosomal protein L19/L19e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_07565 147c9eaffa76a8382e467af3e4a12500 148 Pfam PF01280 Ribosomal protein L19e 2 143 3.6E-58 T 23-10-2018 IPR000196 Ribosomal protein L19/L19e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_07565 147c9eaffa76a8382e467af3e4a12500 148 Gene3D G3DSA:1.10.1200.240 56 147 9.5E-30 T 23-10-2018 A0127_07565 147c9eaffa76a8382e467af3e4a12500 148 Hamap MF_01475 50S ribosomal protein L19e [rpl19e]. 1 147 25.805 T 23-10-2018 IPR000196 Ribosomal protein L19/L19e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_07565 147c9eaffa76a8382e467af3e4a12500 148 SUPERFAMILY SSF48140 1 141 6.8E-57 T 23-10-2018 IPR035970 Ribosomal protein L19/L19e superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_07565 147c9eaffa76a8382e467af3e4a12500 148 Gene3D G3DSA:1.10.1650.10 1 54 3.3E-25 T 23-10-2018 IPR015972 Ribosomal protein L19/L19e, domain 1 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_09645 f725c22512a13ce411c09ade6f1bf7ae 137 Gene3D G3DSA:3.30.300.20 1 122 4.2E-26 T 23-10-2018 IPR015946 K homology domain-like, alpha/beta A0127_09645 f725c22512a13ce411c09ade6f1bf7ae 137 SUPERFAMILY SSF82784 3 124 7.85E-29 T 23-10-2018 IPR036102 OsmC/Ohr superfamily A0127_09645 f725c22512a13ce411c09ade6f1bf7ae 137 Pfam PF02566 OsmC-like protein 35 128 1.2E-19 T 23-10-2018 IPR003718 OsmC/Ohr family A0127_06885 f2948ff01e982c182ad4e9278e4de5e6 380 Hamap MF_01946 Tubulin-like protein CetZ [cetZ]. 1 354 26.837 T 23-10-2018 IPR032907 Tubulin-like protein CetZ GO:0008360 A0127_06885 f2948ff01e982c182ad4e9278e4de5e6 380 SUPERFAMILY SSF52490 3 199 1.7E-40 T 23-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 A0127_06885 f2948ff01e982c182ad4e9278e4de5e6 380 Gene3D G3DSA:3.40.50.1440 1 363 3.2E-87 T 23-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 A0127_06885 f2948ff01e982c182ad4e9278e4de5e6 380 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 25 168 1.1E-25 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A0127_06885 f2948ff01e982c182ad4e9278e4de5e6 380 SMART SM00864 2 199 1.2E-34 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A0127_06885 f2948ff01e982c182ad4e9278e4de5e6 380 PRINTS PR00423 Cell division protein FtsZ signature 183 205 5.2E-10 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A0127_06885 f2948ff01e982c182ad4e9278e4de5e6 380 PRINTS PR00423 Cell division protein FtsZ signature 93 113 5.2E-10 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A0127_06885 f2948ff01e982c182ad4e9278e4de5e6 380 PRINTS PR00423 Cell division protein FtsZ signature 123 144 5.2E-10 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A0127_06885 f2948ff01e982c182ad4e9278e4de5e6 380 ProSitePatterns PS00227 Tubulin subunits alpha, beta, and gamma signature. 101 107 - T 23-10-2018 IPR017975 Tubulin, conserved site GO:0005525|GO:0005874|GO:0007017 Reactome: R-HSA-380320 A0127_08390 e610eae6e848c8a37d0b066992a3cf62 772 Pfam PF01300 Telomere recombination 208 383 1.3E-45 T 23-10-2018 IPR006070 YrdC-like domain GO:0003725 A0127_08390 e610eae6e848c8a37d0b066992a3cf62 772 SUPERFAMILY SSF54975 1 88 3.49E-27 T 23-10-2018 IPR036046 Acylphosphatase-like domain superfamily KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 A0127_08390 e610eae6e848c8a37d0b066992a3cf62 772 Gene3D G3DSA:3.30.420.360 383 755 1.7E-108 T 23-10-2018 A0127_08390 e610eae6e848c8a37d0b066992a3cf62 772 Gene3D G3DSA:3.30.420.350 486 743 1.7E-108 T 23-10-2018 A0127_08390 e610eae6e848c8a37d0b066992a3cf62 772 Gene3D G3DSA:3.90.870.50 6 362 5.9E-145 T 23-10-2018 A0127_08390 e610eae6e848c8a37d0b066992a3cf62 772 SUPERFAMILY SSF55821 175 390 4.58E-44 T 23-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily A0127_08390 e610eae6e848c8a37d0b066992a3cf62 772 Gene3D G3DSA:3.30.110.120 252 371 5.9E-145 T 23-10-2018 A0127_08390 e610eae6e848c8a37d0b066992a3cf62 772 TIGRFAM TIGR00143 hypF: carbamoyltransferase HypF 6 755 8.8E-266 T 23-10-2018 IPR004421 Carbamoyltransferase, HypF-type GO:0016743|GO:0046872|GO:0046944 A0127_08390 e610eae6e848c8a37d0b066992a3cf62 772 Pfam PF07503 HypF finger 158 191 2.2E-15 T 23-10-2018 IPR011125 Zinc finger, HypF-type GO:0008270 A0127_08390 e610eae6e848c8a37d0b066992a3cf62 772 Pfam PF07503 HypF finger 108 141 1.3E-16 T 23-10-2018 IPR011125 Zinc finger, HypF-type GO:0008270 A0127_08390 e610eae6e848c8a37d0b066992a3cf62 772 Pfam PF00814 Glycoprotease family 608 740 8.9E-7 T 23-10-2018 IPR000905 Gcp-like domain A0127_08390 e610eae6e848c8a37d0b066992a3cf62 772 PIRSF PIRSF006256 1 765 1.6E-287 T 23-10-2018 IPR004421 Carbamoyltransferase, HypF-type GO:0016743|GO:0046872|GO:0046944 A0127_08390 e610eae6e848c8a37d0b066992a3cf62 772 SUPERFAMILY SSF53067 403 738 2.04E-6 T 23-10-2018 A0127_08390 e610eae6e848c8a37d0b066992a3cf62 772 Pfam PF00708 Acylphosphatase 4 87 4.5E-25 T 23-10-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 A0127_02330 2280408a2f5c13d727323004bed31f27 264 Gene3D G3DSA:1.10.10.10 2 109 3.3E-21 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A0127_02330 2280408a2f5c13d727323004bed31f27 264 Pfam PF11495 Archaeal transcriptional regulator TrmB 125 263 2.4E-5 T 23-10-2018 IPR021586 Transcription regulator TrmB, C-terminal A0127_02330 2280408a2f5c13d727323004bed31f27 264 Gene3D G3DSA:3.30.870.10 122 264 8.7E-87 T 23-10-2018 A0127_02330 2280408a2f5c13d727323004bed31f27 264 SUPERFAMILY SSF46785 10 96 4.57E-7 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A0127_02330 2280408a2f5c13d727323004bed31f27 264 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 10 78 8.3E-19 T 23-10-2018 IPR002831 Transcription regulator TrmB, N-terminal A0127_08175 88b5e7caea26e6cdc7dbe1da6d5ba8c9 114 SUPERFAMILY SSF53706 2 51 9.85E-8 T 23-10-2018 A0127_08175 88b5e7caea26e6cdc7dbe1da6d5ba8c9 114 Gene3D G3DSA:3.10.530.10 46 112 8.7E-16 T 23-10-2018 IPR036593 CPE0013-like superfamily A0127_08175 88b5e7caea26e6cdc7dbe1da6d5ba8c9 114 SUPERFAMILY SSF160148 46 113 1.44E-18 T 23-10-2018 IPR036593 CPE0013-like superfamily A0127_08175 88b5e7caea26e6cdc7dbe1da6d5ba8c9 114 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 6 32 5.9E-5 T 23-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A0127_08175 88b5e7caea26e6cdc7dbe1da6d5ba8c9 114 Pfam PF07892 Protein of unknown function (DUF1667) 34 112 1.4E-25 T 23-10-2018 IPR012460 Protein of unknown function DUF1667 A0127_04855 52a6e5c4a332d60dcee6b2c7392f4305 416 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 340 415 4.2E-18 T 23-10-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 A0127_04855 52a6e5c4a332d60dcee6b2c7392f4305 416 Pfam PF02475 Met-10+ like-protein 271 329 1.6E-8 T 23-10-2018 IPR030382 SAM-dependent methyltransferase TRM5/TYW2-type Reactome: R-HSA-6782861 A0127_04855 52a6e5c4a332d60dcee6b2c7392f4305 416 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 398 408 - T 23-10-2018 IPR030391 RNA methyltransferase TrmA, conserved site A0127_04855 52a6e5c4a332d60dcee6b2c7392f4305 416 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 347 378 - T 23-10-2018 IPR030390 RNA methyltransferase TrmA, active site A0127_04855 52a6e5c4a332d60dcee6b2c7392f4305 416 SUPERFAMILY SSF53335 60 415 8.37E-73 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A0127_04855 52a6e5c4a332d60dcee6b2c7392f4305 416 Gene3D G3DSA:2.40.50.140 1 61 3.2E-17 T 23-10-2018 A0127_04855 52a6e5c4a332d60dcee6b2c7392f4305 416 SUPERFAMILY SSF50249 3 58 6.85E-9 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A0127_04855 52a6e5c4a332d60dcee6b2c7392f4305 416 Gene3D G3DSA:3.40.1350.30 112 257 4.7E-121 T 23-10-2018 A0127_04855 52a6e5c4a332d60dcee6b2c7392f4305 416 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 9 408 6.3E-88 T 23-10-2018 A0127_04855 52a6e5c4a332d60dcee6b2c7392f4305 416 Gene3D G3DSA:3.40.50.150 73 410 4.7E-121 T 23-10-2018 A0127_04705 096514ea1326c98207306668f377234c 194 Gene3D G3DSA:1.10.10.10 2 82 5.7E-12 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A0127_04705 096514ea1326c98207306668f377234c 194 TIGRFAM TIGR00281 TIGR00281: segregation and condensation protein B 7 175 3.7E-31 T 23-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 A0127_04705 096514ea1326c98207306668f377234c 194 Gene3D G3DSA:1.10.10.10 83 168 9.6E-13 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A0127_04705 096514ea1326c98207306668f377234c 194 SUPERFAMILY SSF46785 3 79 3.6E-13 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A0127_04705 096514ea1326c98207306668f377234c 194 PIRSF PIRSF019345 2 194 1.1E-48 T 23-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 A0127_04705 096514ea1326c98207306668f377234c 194 Pfam PF04079 Segregation and condensation complex subunit ScpB 9 153 1.9E-36 T 23-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 A0127_04705 096514ea1326c98207306668f377234c 194 SUPERFAMILY SSF46785 84 152 1.18E-15 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A0127_06155 1e452a0f885050a5712cb59d53450b9d 319 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 232 318 1.1E-31 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A0127_06155 1e452a0f885050a5712cb59d53450b9d 319 SMART SM00382 34 240 4.0E-10 T 23-10-2018 IPR003593 AAA+ ATPase domain A0127_06155 1e452a0f885050a5712cb59d53450b9d 319 Gene3D G3DSA:3.40.50.300 3 319 1.5E-103 T 23-10-2018 A0127_06155 1e452a0f885050a5712cb59d53450b9d 319 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A0127_06155 1e452a0f885050a5712cb59d53450b9d 319 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 234 298 1.9E-20 T 23-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 A0127_06155 1e452a0f885050a5712cb59d53450b9d 319 SUPERFAMILY SSF52540 5 254 4.09E-68 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_06155 1e452a0f885050a5712cb59d53450b9d 319 Pfam PF00005 ABC transporter 26 182 6.5E-28 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A0127_09670 7b8080db4853b5a544c7b30a320d2a68 220 Pfam PF01963 TraB family 9 216 1.1E-12 T 23-10-2018 IPR002816 Pheromone shutdown, TraB A0127_07655 ffac7b264157956c4439be6caad1cdc8 180 Gene3D G3DSA:3.10.290.10 102 176 1.5E-17 T 23-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 A0127_07655 ffac7b264157956c4439be6caad1cdc8 180 SMART SM01390 5 102 1.3E-10 T 23-10-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 A0127_07655 ffac7b264157956c4439be6caad1cdc8 180 SUPERFAMILY SSF55174 9 160 1.59E-34 T 23-10-2018 A0127_07655 ffac7b264157956c4439be6caad1cdc8 180 ProSitePatterns PS00632 Ribosomal protein S4 signature. 101 125 - T 23-10-2018 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_07655 ffac7b264157956c4439be6caad1cdc8 180 Pfam PF01479 S4 domain 103 148 1.1E-17 T 23-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_07655 ffac7b264157956c4439be6caad1cdc8 180 TIGRFAM TIGR01018 uS4_arch: ribosomal protein uS4 1 161 3.2E-75 T 23-10-2018 IPR005710 Ribosomal protein S4/S9, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_07655 ffac7b264157956c4439be6caad1cdc8 180 Hamap MF_01306_A 30S ribosomal protein S4 [rpsD]. 1 156 34.471 T 23-10-2018 IPR022802 Ribosomal protein S4, archaeal GO:0006412|GO:0019843 A0127_07655 ffac7b264157956c4439be6caad1cdc8 180 SMART SM00363 103 165 1.2E-15 T 23-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_01545 bd3bd043f5fbb3d4ad28ca1b1cc89cc9 333 Hamap MF_00776 Glyoxylate reductase [gyaR]. 1 331 61.168 T 23-10-2018 IPR023519 Glyoxylate reductase GyaR GO:0047964|GO:0055114 KEGG: 00630+1.1.1.26|MetaCyc: PWY-7294|MetaCyc: PWY-7295 A0127_01545 bd3bd043f5fbb3d4ad28ca1b1cc89cc9 333 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 5 322 2.2E-37 T 23-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 A0127_01545 bd3bd043f5fbb3d4ad28ca1b1cc89cc9 333 Gene3D G3DSA:3.40.50.720 98 290 4.6E-142 T 23-10-2018 A0127_01545 bd3bd043f5fbb3d4ad28ca1b1cc89cc9 333 SUPERFAMILY SSF51735 103 290 1.47E-65 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A0127_01545 bd3bd043f5fbb3d4ad28ca1b1cc89cc9 333 SUPERFAMILY SSF52283 2 133 1.4E-42 T 23-10-2018 A0127_01545 bd3bd043f5fbb3d4ad28ca1b1cc89cc9 333 Gene3D G3DSA:3.40.50.720 4 317 4.6E-142 T 23-10-2018 A0127_01545 bd3bd043f5fbb3d4ad28ca1b1cc89cc9 333 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 230 246 - T 23-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site A0127_01545 bd3bd043f5fbb3d4ad28ca1b1cc89cc9 333 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 153 180 - T 23-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 A0127_01545 bd3bd043f5fbb3d4ad28ca1b1cc89cc9 333 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 110 290 4.8E-68 T 23-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 A0127_08490 404ee9571689e838be1aa025846e2166 400 SUPERFAMILY SSF53218 181 324 4.58E-42 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily A0127_08490 404ee9571689e838be1aa025846e2166 400 Pfam PF03454 MoeA C-terminal region (domain IV) 335 399 1.8E-18 T 23-10-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A0127_08490 404ee9571689e838be1aa025846e2166 400 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 180 317 2.9E-32 T 23-10-2018 IPR001453 MoaB/Mog domain A0127_08490 404ee9571689e838be1aa025846e2166 400 SUPERFAMILY SSF63882 7 180 7.33E-57 T 23-10-2018 IPR036135 MoeA, N-terminal and linker domain superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A0127_08490 404ee9571689e838be1aa025846e2166 400 Pfam PF03453 MoeA N-terminal region (domain I and II) 8 171 2.0E-43 T 23-10-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A0127_08490 404ee9571689e838be1aa025846e2166 400 Gene3D G3DSA:2.40.340.10 329 400 4.9E-26 T 23-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A0127_08490 404ee9571689e838be1aa025846e2166 400 Pfam PF00994 Probable molybdopterin binding domain 184 320 2.6E-23 T 23-10-2018 IPR001453 MoaB/Mog domain A0127_08490 404ee9571689e838be1aa025846e2166 400 Gene3D G3DSA:2.170.190.11 49 145 6.4E-113 T 23-10-2018 A0127_08490 404ee9571689e838be1aa025846e2166 400 Gene3D G3DSA:3.40.980.10 179 320 6.4E-113 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily A0127_08490 404ee9571689e838be1aa025846e2166 400 Gene3D G3DSA:3.90.105.10 26 178 6.4E-113 T 23-10-2018 A0127_08490 404ee9571689e838be1aa025846e2166 400 SUPERFAMILY SSF63867 330 399 1.7E-18 T 23-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A0127_08490 404ee9571689e838be1aa025846e2166 400 SMART SM00852 184 321 1.3E-38 T 23-10-2018 IPR001453 MoaB/Mog domain A0127_08575 e532dffe479ddb7e9024b295d025f20d 211 Gene3D G3DSA:1.10.10.10 1 83 8.5E-17 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A0127_08575 e532dffe479ddb7e9024b295d025f20d 211 SMART SM00419 14 66 2.2E-8 T 23-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 A0127_08575 e532dffe479ddb7e9024b295d025f20d 211 Pfam PF01982 Domain of unknown function DUF120 92 209 4.9E-39 T 23-10-2018 IPR023602 Riboflavin kinase domain, CTP-dependent GO:0016773 KEGG: 00740+2.7.1.161|MetaCyc: PWY-6167 A0127_08575 e532dffe479ddb7e9024b295d025f20d 211 Hamap MF_01285 Riboflavin kinase [ribK]. 86 209 24.74 T 23-10-2018 IPR023470 Riboflavin kinase, archaeal GO:0008531|GO:0009231 KEGG: 00740+2.7.1.161|MetaCyc: PWY-6167 A0127_08575 e532dffe479ddb7e9024b295d025f20d 211 Gene3D G3DSA:2.40.30.30 84 211 8.8E-42 T 23-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 A0127_08575 e532dffe479ddb7e9024b295d025f20d 211 SUPERFAMILY SSF82114 86 209 1.05E-40 T 23-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 A0127_08575 e532dffe479ddb7e9024b295d025f20d 211 SUPERFAMILY SSF46785 21 80 4.5E-13 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A0127_08575 e532dffe479ddb7e9024b295d025f20d 211 Pfam PF13545 Crp-like helix-turn-helix domain 7 65 8.5E-10 T 23-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 A0127_06385 324cc7d4dc348f03c1ac0c6fa48be918 1067 Gene3D G3DSA:3.90.740.10 199 405 4.2E-232 T 23-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 A0127_06385 324cc7d4dc348f03c1ac0c6fa48be918 1067 SUPERFAMILY SSF50677 203 401 1.26E-53 T 23-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 A0127_06385 324cc7d4dc348f03c1ac0c6fa48be918 1067 Gene3D G3DSA:3.40.50.620 16 651 4.2E-232 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A0127_06385 324cc7d4dc348f03c1ac0c6fa48be918 1067 SUPERFAMILY SSF52374 3 674 5.14E-135 T 23-10-2018 A0127_06385 324cc7d4dc348f03c1ac0c6fa48be918 1067 SUPERFAMILY SSF47323 676 918 2.43E-63 T 23-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A0127_06385 324cc7d4dc348f03c1ac0c6fa48be918 1067 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 42 53 1.6E-29 T 23-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A0127_06385 324cc7d4dc348f03c1ac0c6fa48be918 1067 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 584 593 1.6E-29 T 23-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A0127_06385 324cc7d4dc348f03c1ac0c6fa48be918 1067 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 223 246 1.6E-29 T 23-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A0127_06385 324cc7d4dc348f03c1ac0c6fa48be918 1067 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 545 558 1.6E-29 T 23-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A0127_06385 324cc7d4dc348f03c1ac0c6fa48be918 1067 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 399 414 1.6E-29 T 23-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A0127_06385 324cc7d4dc348f03c1ac0c6fa48be918 1067 Hamap MF_02003 Isoleucine--tRNA ligase [ileS]. 3 1066 13.736 T 23-10-2018 IPR023586 Isoleucine-tRNA ligase, type 2 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A0127_06385 324cc7d4dc348f03c1ac0c6fa48be918 1067 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 11 876 0.0 T 23-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 A0127_06385 324cc7d4dc348f03c1ac0c6fa48be918 1067 Gene3D G3DSA:1.10.30.30 902 958 1.8E-5 T 23-10-2018 A0127_06385 324cc7d4dc348f03c1ac0c6fa48be918 1067 Pfam PF08264 Anticodon-binding domain of tRNA 711 862 2.5E-38 T 23-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 A0127_06385 324cc7d4dc348f03c1ac0c6fa48be918 1067 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 21 663 5.3E-189 T 23-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 A0127_06385 324cc7d4dc348f03c1ac0c6fa48be918 1067 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 49 60 - T 23-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A0127_06385 324cc7d4dc348f03c1ac0c6fa48be918 1067 SUPERFAMILY SSF47323 984 1051 1.24E-6 T 23-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A0127_06385 324cc7d4dc348f03c1ac0c6fa48be918 1067 Gene3D G3DSA:1.10.730.10 670 853 4.3E-55 T 23-10-2018 A0127_08875 f24c7a575ef795c27c7d05b6494384c5 153 SUPERFAMILY SSF54909 67 144 5.01E-18 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel A0127_08875 f24c7a575ef795c27c7d05b6494384c5 153 Pfam PF13404 AsnC-type helix-turn-helix domain 7 47 3.8E-17 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A0127_08875 f24c7a575ef795c27c7d05b6494384c5 153 Gene3D G3DSA:3.30.70.920 59 148 3.0E-22 T 23-10-2018 A0127_08875 f24c7a575ef795c27c7d05b6494384c5 153 SUPERFAMILY SSF46785 7 67 2.45E-16 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A0127_08875 f24c7a575ef795c27c7d05b6494384c5 153 Gene3D G3DSA:1.10.10.10 5 58 6.9E-22 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A0127_08875 f24c7a575ef795c27c7d05b6494384c5 153 Pfam PF01037 Lrp/AsnC ligand binding domain 73 142 1.3E-16 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A0127_08875 f24c7a575ef795c27c7d05b6494384c5 153 SMART SM00344 7 113 6.8E-45 T 23-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A0127_08875 f24c7a575ef795c27c7d05b6494384c5 153 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 34 53 2.3E-16 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A0127_08875 f24c7a575ef795c27c7d05b6494384c5 153 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 7 23 2.3E-16 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A0127_08875 f24c7a575ef795c27c7d05b6494384c5 153 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 23 34 2.3E-16 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A0127_02995 dce98ed9ae1daed1d3fd6df441ed00df 80 SUPERFAMILY SSF82697 3 78 1.08E-24 T 23-10-2018 IPR036604 Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A0127_02995 dce98ed9ae1daed1d3fd6df441ed00df 80 ProDom PD010362 PHOSPHORIBOSYLFORMYLGLYCINAMIDINE PURS SYNTHETASE SYNTHASE COMPONENT SYNTHASE LIGASE FGAM UPF0062 I 10 77 2.0E-27 T 23-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A0127_02995 dce98ed9ae1daed1d3fd6df441ed00df 80 Pfam PF02700 Phosphoribosylformylglycinamidine (FGAM) synthase 4 75 2.9E-26 T 23-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A0127_02995 dce98ed9ae1daed1d3fd6df441ed00df 80 Gene3D G3DSA:3.30.1280.10 1 80 2.5E-28 T 23-10-2018 IPR036604 Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A0127_02995 dce98ed9ae1daed1d3fd6df441ed00df 80 TIGRFAM TIGR00302 TIGR00302: phosphoribosylformylglycinamidine synthase, purS protein 4 77 1.7E-24 T 23-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A0127_02995 dce98ed9ae1daed1d3fd6df441ed00df 80 Hamap MF_01926 Phosphoribosylformylglycinamidine synthase subunit PurS [purS]. 3 76 20.261 T 23-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A0127_05165 1b77074490f0ada7e3c463b8e2b5ce8b 203 Gene3D G3DSA:3.40.50.11570 1 202 1.7E-43 T 23-10-2018 A0127_05165 1b77074490f0ada7e3c463b8e2b5ce8b 203 Pfam PF03192 Pyrococcus protein of unknown function, DUF257 5 201 6.0E-58 T 23-10-2018 IPR005489 Protein of unknown function DUF257 A0127_08565 5b20d7543437099480114d22b1b0fe8a 392 SMART SM00729 21 234 0.0028 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A0127_08565 5b20d7543437099480114d22b1b0fe8a 392 Gene3D G3DSA:3.20.20.70 20 317 7.9E-12 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A0127_08565 5b20d7543437099480114d22b1b0fe8a 392 Pfam PF04055 Radical SAM superfamily 27 195 1.8E-12 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A0127_08565 5b20d7543437099480114d22b1b0fe8a 392 SUPERFAMILY SSF102114 25 312 1.7E-14 T 23-10-2018 A0127_00505 734733eb696c597e9d9b6aedf8f913db 568 Gene3D G3DSA:3.30.56.10 1 80 1.5E-22 T 23-10-2018 A0127_00505 734733eb696c597e9d9b6aedf8f913db 568 SUPERFAMILY SSF55681 345 562 3.73E-44 T 23-10-2018 A0127_00505 734733eb696c597e9d9b6aedf8f913db 568 Gene3D G3DSA:3.30.930.10 365 563 2.4E-51 T 23-10-2018 A0127_00505 734733eb696c597e9d9b6aedf8f913db 568 TIGRFAM TIGR00471 pheT_arch: phenylalanine--tRNA ligase, beta subunit 1 557 1.9E-176 T 23-10-2018 IPR004531 Phenylalanyl-tRNA synthetase, class IIc, beta subunit, archae/euk cytosolic GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 A0127_00505 734733eb696c597e9d9b6aedf8f913db 568 Pfam PF03483 B3/4 domain 119 243 4.4E-15 T 23-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 A0127_00505 734733eb696c597e9d9b6aedf8f913db 568 Hamap MF_00284 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 560 36.078 T 23-10-2018 IPR022918 Phenylalanine-tRNA ligase beta chain 2, bacterial/archaeal GO:0004826 KEGG: 00970+6.1.1.20 A0127_00505 734733eb696c597e9d9b6aedf8f913db 568 Gene3D G3DSA:3.50.40.10 81 278 9.1E-74 T 23-10-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 KEGG: 00970+6.1.1.20 A0127_00505 734733eb696c597e9d9b6aedf8f913db 568 SUPERFAMILY SSF46955 5 81 6.41E-9 T 23-10-2018 IPR009061 Putative DNA-binding domain superfamily A0127_00505 734733eb696c597e9d9b6aedf8f913db 568 SUPERFAMILY SSF56037 142 259 2.88E-5 T 23-10-2018 A0127_00505 734733eb696c597e9d9b6aedf8f913db 568 Gene3D G3DSA:3.30.56.10 279 348 8.9E-28 T 23-10-2018 A0127_00505 734733eb696c597e9d9b6aedf8f913db 568 SMART SM00873 100 259 2.5E-21 T 23-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 A0127_00505 734733eb696c597e9d9b6aedf8f913db 568 SMART SM00874 280 348 8.1E-18 T 23-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 A0127_00505 734733eb696c597e9d9b6aedf8f913db 568 SUPERFAMILY SSF46955 281 352 2.47E-16 T 23-10-2018 IPR009061 Putative DNA-binding domain superfamily A0127_00505 734733eb696c597e9d9b6aedf8f913db 568 Pfam PF03484 tRNA synthetase B5 domain 284 348 8.5E-15 T 23-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 A0127_03840 be3f7dacc77cd9eaf952ad09b9adad5a 774 Pfam PF00136 DNA polymerase family B 352 746 1.9E-83 T 23-10-2018 IPR006134 DNA-directed DNA polymerase, family B, multifunctional domain GO:0000166|GO:0003677 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A0127_03840 be3f7dacc77cd9eaf952ad09b9adad5a 774 SUPERFAMILY SSF56672 349 761 8.9E-135 T 23-10-2018 A0127_03840 be3f7dacc77cd9eaf952ad09b9adad5a 774 Gene3D G3DSA:3.30.342.10 3 365 8.5E-173 T 23-10-2018 A0127_03840 be3f7dacc77cd9eaf952ad09b9adad5a 774 ProSitePatterns PS00116 DNA polymerase family B signature. 538 546 - T 23-10-2018 IPR017964 DNA-directed DNA polymerase, family B, conserved site GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A0127_03840 be3f7dacc77cd9eaf952ad09b9adad5a 774 Pfam PF03104 DNA polymerase family B, exonuclease domain 130 278 1.1E-34 T 23-10-2018 IPR006133 DNA-directed DNA polymerase, family B, exonuclease domain KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A0127_03840 be3f7dacc77cd9eaf952ad09b9adad5a 774 Pfam PF03104 DNA polymerase family B, exonuclease domain 22 129 1.2E-12 T 23-10-2018 IPR006133 DNA-directed DNA polymerase, family B, exonuclease domain KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A0127_03840 be3f7dacc77cd9eaf952ad09b9adad5a 774 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 536 544 8.9E-10 T 23-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A0127_03840 be3f7dacc77cd9eaf952ad09b9adad5a 774 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 483 495 8.9E-10 T 23-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A0127_03840 be3f7dacc77cd9eaf952ad09b9adad5a 774 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 400 413 8.9E-10 T 23-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A0127_03840 be3f7dacc77cd9eaf952ad09b9adad5a 774 TIGRFAM TIGR00592 pol2: DNA polymerase (pol2) 446 745 2.8E-113 T 23-10-2018 A0127_03840 be3f7dacc77cd9eaf952ad09b9adad5a 774 TIGRFAM TIGR00592 pol2: DNA polymerase (pol2) 65 443 6.3E-84 T 23-10-2018 A0127_03840 be3f7dacc77cd9eaf952ad09b9adad5a 774 Gene3D G3DSA:3.30.420.10 131 347 8.5E-173 T 23-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 A0127_03840 be3f7dacc77cd9eaf952ad09b9adad5a 774 Gene3D G3DSA:1.10.287.690 448 499 1.1E-23 T 23-10-2018 A0127_03840 be3f7dacc77cd9eaf952ad09b9adad5a 774 SMART SM00486 133 550 1.6E-143 T 23-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A0127_03840 be3f7dacc77cd9eaf952ad09b9adad5a 774 SUPERFAMILY SSF53098 1 346 4.2E-90 T 23-10-2018 IPR012337 Ribonuclease H-like superfamily A0127_03840 be3f7dacc77cd9eaf952ad09b9adad5a 774 Gene3D G3DSA:1.10.132.60 607 773 1.6E-63 T 23-10-2018 A0127_04620 8b86c71a0784ea499994ca90f365c86b 214 PIRSF PIRSF019202 1 214 2.7E-49 T 23-10-2018 IPR007366 Protein of unknown function DUF432 A0127_04620 8b86c71a0784ea499994ca90f365c86b 214 Pfam PF04254 Protein of unknown function (DUF432) 52 166 5.2E-29 T 23-10-2018 IPR007366 Protein of unknown function DUF432 A0127_07190 c71de0a9eada458e65306f852744beeb 406 Gene3D G3DSA:3.10.310.40 302 404 1.6E-7 T 23-10-2018 A0127_07190 c71de0a9eada458e65306f852744beeb 406 Gene3D G3DSA:2.40.30.130 1 92 8.4E-22 T 23-10-2018 A0127_07190 c71de0a9eada458e65306f852744beeb 406 Pfam PF01411 tRNA synthetases class II (A) 26 94 2.5E-11 T 23-10-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 A0127_07190 c71de0a9eada458e65306f852744beeb 406 SMART SM00863 191 234 2.9E-14 T 23-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 A0127_07190 c71de0a9eada458e65306f852744beeb 406 Pfam PF02272 DHHA1 domain 273 399 2.6E-10 T 23-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 A0127_07190 c71de0a9eada458e65306f852744beeb 406 SUPERFAMILY SSF50447 1 90 8.47E-16 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily A0127_07190 c71de0a9eada458e65306f852744beeb 406 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 191 234 4.5E-11 T 23-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 A0127_07190 c71de0a9eada458e65306f852744beeb 406 Gene3D G3DSA:3.30.980.10 93 247 1.2E-40 T 23-10-2018 A0127_07190 c71de0a9eada458e65306f852744beeb 406 SUPERFAMILY SSF55186 93 238 3.01E-36 T 23-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 A0127_00825 e9d3d8b305d5bb7b84d34ad5c8c5b7c8 346 Gene3D G3DSA:3.40.50.1980 65 186 3.2E-34 T 23-10-2018 A0127_00825 e9d3d8b305d5bb7b84d34ad5c8c5b7c8 346 SUPERFAMILY SSF53807 66 330 5.49E-71 T 23-10-2018 A0127_00825 e9d3d8b305d5bb7b84d34ad5c8c5b7c8 346 Pfam PF01497 Periplasmic binding protein 87 304 8.2E-37 T 23-10-2018 IPR002491 ABC transporter periplasmic binding domain A0127_00825 e9d3d8b305d5bb7b84d34ad5c8c5b7c8 346 Gene3D G3DSA:3.40.50.1980 204 330 1.2E-35 T 23-10-2018 A0127_08460 4861e6bc617403afe6d4f893cd049eb2 194 Gene3D G3DSA:3.30.60.20 144 194 8.3E-25 T 23-10-2018 A0127_08460 4861e6bc617403afe6d4f893cd049eb2 194 ProSitePatterns PS00603 Thymidine kinase cellular-type signature. 176 189 - T 23-10-2018 IPR020633 Thymidine kinase, conserved site GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 A0127_08460 4861e6bc617403afe6d4f893cd049eb2 194 Pfam PF00265 Thymidine kinase 6 189 1.4E-52 T 23-10-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 A0127_08460 4861e6bc617403afe6d4f893cd049eb2 194 Gene3D G3DSA:3.40.50.300 1 143 1.6E-46 T 23-10-2018 A0127_08460 4861e6bc617403afe6d4f893cd049eb2 194 Hamap MF_00124 Thymidine kinase [tdk]. 4 192 36.239 T 23-10-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 A0127_08460 4861e6bc617403afe6d4f893cd049eb2 194 SUPERFAMILY SSF57716 144 192 7.13E-16 T 23-10-2018 A0127_08460 4861e6bc617403afe6d4f893cd049eb2 194 PIRSF PIRSF035805 3 194 1.1E-66 T 23-10-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 A0127_08460 4861e6bc617403afe6d4f893cd049eb2 194 SUPERFAMILY SSF52540 5 143 5.57E-39 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_07640 71752cabd0f21d3064e0541f9e8142a9 195 Pfam PF05175 Methyltransferase small domain 28 191 3.2E-44 T 23-10-2018 IPR007848 Methyltransferase small domain GO:0008168 A0127_07640 71752cabd0f21d3064e0541f9e8142a9 195 Gene3D G3DSA:3.40.50.150 5 193 4.3E-50 T 23-10-2018 A0127_07640 71752cabd0f21d3064e0541f9e8142a9 195 SUPERFAMILY SSF53335 9 190 2.91E-41 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A0127_00375 bd3ba5c87c9a005ff33b23a54e9cdd48 602 Pfam PF00437 Type II/IV secretion system protein 213 370 2.4E-9 T 23-10-2018 IPR001482 Type II/IV secretion system protein A0127_00375 bd3ba5c87c9a005ff33b23a54e9cdd48 602 SUPERFAMILY SSF52540 134 438 2.44E-29 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_00375 bd3ba5c87c9a005ff33b23a54e9cdd48 602 SUPERFAMILY SSF88723 2 132 1.67E-15 T 23-10-2018 IPR029060 PIN-like domain superfamily A0127_00375 bd3ba5c87c9a005ff33b23a54e9cdd48 602 Gene3D G3DSA:3.40.50.300 239 426 2.1E-17 T 23-10-2018 A0127_00375 bd3ba5c87c9a005ff33b23a54e9cdd48 602 SUPERFAMILY SSF54814 464 520 4.51E-6 T 23-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 A0127_00375 bd3ba5c87c9a005ff33b23a54e9cdd48 602 SMART SM00670 2 115 2.8E-19 T 23-10-2018 IPR002716 PIN domain A0127_00375 bd3ba5c87c9a005ff33b23a54e9cdd48 602 Gene3D G3DSA:3.40.50.1010 1 127 1.2E-31 T 23-10-2018 A0127_02625 0fe8c560eaf3d5d9596ff91fad4cdb16 224 Gene3D G3DSA:2.40.100.10 83 223 3.0E-65 T 23-10-2018 IPR029000 Cyclophilin-like domain superfamily A0127_02625 0fe8c560eaf3d5d9596ff91fad4cdb16 224 Pfam PF02682 Carboxyltransferase domain, subdomain C and D 1 198 3.8E-77 T 23-10-2018 IPR003833 Carboxyltransferase domain, subdomain C and D A0127_02625 0fe8c560eaf3d5d9596ff91fad4cdb16 224 Gene3D G3DSA:3.30.1360.40 1 82 6.8E-26 T 23-10-2018 A0127_02625 0fe8c560eaf3d5d9596ff91fad4cdb16 224 SMART SM00796 1 198 3.3E-110 T 23-10-2018 IPR003833 Carboxyltransferase domain, subdomain C and D A0127_02625 0fe8c560eaf3d5d9596ff91fad4cdb16 224 TIGRFAM TIGR00370 TIGR00370: sensor histidine kinase inhibitor, KipI family 4 207 3.5E-71 T 23-10-2018 IPR010016 KipI family KEGG: 00480+3.5.2.9|MetaCyc: PWY-4041|MetaCyc: PWY-7942 A0127_02625 0fe8c560eaf3d5d9596ff91fad4cdb16 224 SUPERFAMILY SSF50891 84 214 2.81E-51 T 23-10-2018 IPR029000 Cyclophilin-like domain superfamily A0127_02625 0fe8c560eaf3d5d9596ff91fad4cdb16 224 SUPERFAMILY SSF160467 1 88 4.32E-21 T 23-10-2018 A0127_05465 29e6fda1f9827e11bef1f3a6dc0b45ee 310 SUPERFAMILY SSF102114 200 283 6.28E-11 T 23-10-2018 A0127_05465 29e6fda1f9827e11bef1f3a6dc0b45ee 310 Pfam PF13186 Iron-sulfur cluster-binding domain 222 278 3.0E-7 T 23-10-2018 IPR023885 4Fe4S-binding SPASM domain A0127_05465 29e6fda1f9827e11bef1f3a6dc0b45ee 310 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 219 303 1.5E-10 T 23-10-2018 IPR023885 4Fe4S-binding SPASM domain A0127_05465 29e6fda1f9827e11bef1f3a6dc0b45ee 310 Gene3D G3DSA:3.20.20.70 107 308 3.0E-11 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A0127_00400 8eb50e5c500b5fb1994f40d2d59d6cc9 339 PIRSF PIRSF004930 2 339 6.9E-131 T 23-10-2018 IPR010923 tRNA threonylcarbamoyladenosine biosynthesis protein SUA5 A0127_00400 8eb50e5c500b5fb1994f40d2d59d6cc9 339 Gene3D G3DSA:3.90.870.10 3 212 2.4E-83 T 23-10-2018 A0127_00400 8eb50e5c500b5fb1994f40d2d59d6cc9 339 SUPERFAMILY SSF55821 9 209 2.53E-68 T 23-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily A0127_00400 8eb50e5c500b5fb1994f40d2d59d6cc9 339 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 12 207 4.1E-67 T 23-10-2018 IPR006070 YrdC-like domain GO:0003725 A0127_00400 8eb50e5c500b5fb1994f40d2d59d6cc9 339 Pfam PF01300 Telomere recombination 22 196 5.0E-59 T 23-10-2018 IPR006070 YrdC-like domain GO:0003725 A0127_00400 8eb50e5c500b5fb1994f40d2d59d6cc9 339 Pfam PF03481 Putative GTP-binding controlling metal-binding 199 333 1.3E-29 T 23-10-2018 IPR005145 Putative GTP-binding controlling metal-binding domain A0127_00400 8eb50e5c500b5fb1994f40d2d59d6cc9 339 Gene3D G3DSA:3.40.50.11030 214 339 8.0E-39 T 23-10-2018 IPR038385 Threonylcarbamoyl-AMP synthase, C-terminal domain superfamily A0127_08540 45662d6ab94d9fe70c6eb99b6cc2ecab 325 Pfam PF00155 Aminotransferase class I and II 30 316 8.5E-34 T 23-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A0127_08540 45662d6ab94d9fe70c6eb99b6cc2ecab 325 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 190 199 - T 23-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 A0127_08540 45662d6ab94d9fe70c6eb99b6cc2ecab 325 SUPERFAMILY SSF53383 10 319 1.18E-52 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A0127_08540 45662d6ab94d9fe70c6eb99b6cc2ecab 325 Gene3D G3DSA:3.40.640.10 32 235 1.3E-69 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A0127_08540 45662d6ab94d9fe70c6eb99b6cc2ecab 325 Gene3D G3DSA:3.90.1150.10 21 317 1.3E-69 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A0127_03090 a364597652050c89f42d20fbf6b0143a 388 PIRSF PIRSF000429 1 385 2.2E-64 T 23-10-2018 IPR002155 Thiolase GO:0016747 A0127_03090 a364597652050c89f42d20fbf6b0143a 388 SUPERFAMILY SSF53901 246 375 2.68E-28 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 A0127_03090 a364597652050c89f42d20fbf6b0143a 388 Pfam PF00108 Thiolase, N-terminal domain 5 221 9.3E-24 T 23-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 A0127_03090 a364597652050c89f42d20fbf6b0143a 388 Pfam PF02803 Thiolase, C-terminal domain 260 355 9.4E-11 T 23-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 A0127_03090 a364597652050c89f42d20fbf6b0143a 388 Gene3D G3DSA:3.40.47.10 5 387 8.2E-121 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 A0127_03090 a364597652050c89f42d20fbf6b0143a 388 SUPERFAMILY SSF53901 5 229 5.26E-44 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 A0127_07555 f60a381742b5694d0ef3ab8320066f38 184 TIGRFAM TIGR03653 uL6_arch: ribosomal protein uL6 8 177 3.7E-80 T 23-10-2018 IPR019907 Ribosomal protein L6P, archaea GO:0003735|GO:0005840|GO:0006412|GO:0019843 A0127_07555 f60a381742b5694d0ef3ab8320066f38 184 SUPERFAMILY SSF56053 86 177 6.84E-31 T 23-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_07555 f60a381742b5694d0ef3ab8320066f38 184 Pfam PF00347 Ribosomal protein L6 13 85 4.1E-19 T 23-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_07555 f60a381742b5694d0ef3ab8320066f38 184 Pfam PF00347 Ribosomal protein L6 97 171 2.3E-16 T 23-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_07555 f60a381742b5694d0ef3ab8320066f38 184 PIRSF PIRSF002162 5 182 4.8E-41 T 23-10-2018 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_07555 f60a381742b5694d0ef3ab8320066f38 184 Hamap MF_01365_A 50S ribosomal protein L6 [rplF]. 2 178 39.554 T 23-10-2018 IPR019907 Ribosomal protein L6P, archaea GO:0003735|GO:0005840|GO:0006412|GO:0019843 A0127_07555 f60a381742b5694d0ef3ab8320066f38 184 SUPERFAMILY SSF56053 8 85 1.83E-23 T 23-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_07555 f60a381742b5694d0ef3ab8320066f38 184 Gene3D G3DSA:3.90.930.12 86 182 5.3E-38 T 23-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_07555 f60a381742b5694d0ef3ab8320066f38 184 Gene3D G3DSA:3.90.930.12 7 85 1.4E-31 T 23-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_07555 f60a381742b5694d0ef3ab8320066f38 184 ProSitePatterns PS00700 Ribosomal protein L6 signature 2. 156 177 - T 23-10-2018 IPR002359 Ribosomal protein L6, conserved site-2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_02585 fb4a2cbf86677fbd30a4ac608eaac8f2 279 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 108 251 1.3E-10 T 23-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 A0127_02585 fb4a2cbf86677fbd30a4ac608eaac8f2 279 SMART SM00478 112 270 4.5E-14 T 23-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 A0127_02585 fb4a2cbf86677fbd30a4ac608eaac8f2 279 Gene3D G3DSA:1.10.340.30 101 217 2.8E-25 T 23-10-2018 A0127_02585 fb4a2cbf86677fbd30a4ac608eaac8f2 279 Gene3D G3DSA:1.10.1670.10 218 275 9.8E-8 T 23-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 A0127_02585 fb4a2cbf86677fbd30a4ac608eaac8f2 279 SUPERFAMILY SSF48150 91 269 1.34E-34 T 23-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 A0127_04005 6cd7fcca5cfabc5acc3cad0c1dcc6b76 256 SUPERFAMILY SSF52540 1 254 1.03E-58 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_04005 6cd7fcca5cfabc5acc3cad0c1dcc6b76 256 Pfam PF13614 AAA domain 4 178 9.7E-54 T 23-10-2018 IPR025669 AAA domain A0127_04005 6cd7fcca5cfabc5acc3cad0c1dcc6b76 256 PIRSF PIRSF009320 2 48 7.7E-14 T 23-10-2018 A0127_04005 6cd7fcca5cfabc5acc3cad0c1dcc6b76 256 PIRSF PIRSF009320 91 256 5.8E-7 T 23-10-2018 A0127_04005 6cd7fcca5cfabc5acc3cad0c1dcc6b76 256 Gene3D G3DSA:3.40.50.300 1 255 7.9E-74 T 23-10-2018 A0127_04025 3c9da9a200164e414795d583444e6a36 392 Pfam PF00155 Aminotransferase class I and II 34 384 2.6E-72 T 23-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A0127_04025 3c9da9a200164e414795d583444e6a36 392 SUPERFAMILY SSF53383 10 391 2.69E-124 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A0127_04025 3c9da9a200164e414795d583444e6a36 392 Gene3D G3DSA:3.40.640.10 65 284 2.0E-133 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A0127_04025 3c9da9a200164e414795d583444e6a36 392 Gene3D G3DSA:3.90.1150.10 34 384 2.0E-133 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A0127_04025 3c9da9a200164e414795d583444e6a36 392 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 234 247 - T 23-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 A0127_08250 8fcd5b47d0495c380027cdbed4fef9ef 222 TIGRFAM TIGR01091 upp: uracil phosphoribosyltransferase 15 218 3.0E-76 T 23-10-2018 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 A0127_08250 8fcd5b47d0495c380027cdbed4fef9ef 222 Hamap MF_01218_A Uracil phosphoribosyltransferase [upp]. 9 217 40.218 T 23-10-2018 IPR034331 Uracil phosphoribosyltransferase, archaea GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 A0127_08250 8fcd5b47d0495c380027cdbed4fef9ef 222 Pfam PF14681 Uracil phosphoribosyltransferase 15 217 8.2E-49 T 23-10-2018 A0127_08250 8fcd5b47d0495c380027cdbed4fef9ef 222 SUPERFAMILY SSF53271 13 217 6.95E-55 T 23-10-2018 IPR029057 Phosphoribosyltransferase-like A0127_08250 8fcd5b47d0495c380027cdbed4fef9ef 222 Gene3D G3DSA:3.40.50.2020 13 217 4.7E-58 T 23-10-2018 A0127_00720 686033a1dbd75a5998421c03bbc25337 309 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 233 249 8.6E-30 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A0127_00720 686033a1dbd75a5998421c03bbc25337 309 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 117 127 8.6E-30 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A0127_00720 686033a1dbd75a5998421c03bbc25337 309 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 183 195 8.6E-30 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A0127_00720 686033a1dbd75a5998421c03bbc25337 309 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 291 308 8.6E-30 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A0127_00720 686033a1dbd75a5998421c03bbc25337 309 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 88 102 8.6E-30 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A0127_00720 686033a1dbd75a5998421c03bbc25337 309 Gene3D G3DSA:3.40.50.150 103 309 2.7E-69 T 23-10-2018 A0127_00720 686033a1dbd75a5998421c03bbc25337 309 Pfam PF17125 N-terminal domain of 16S rRNA methyltransferase RsmF 12 102 1.5E-18 T 23-10-2018 IPR031341 Ribosomal RNA small subunit methyltransferase F, N-terminal Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 A0127_00720 686033a1dbd75a5998421c03bbc25337 309 ProSitePatterns PS01153 NOL1/NOP2/sun family signature. 182 193 - T 23-10-2018 IPR018314 Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site GO:0003723|GO:0008168 A0127_00720 686033a1dbd75a5998421c03bbc25337 309 TIGRFAM TIGR00446 nop2p: NOL1/NOP2/sun family putative RNA methylase 42 308 4.3E-89 T 23-10-2018 IPR011023 Nop2p GO:0003723|GO:0006364|GO:0008757 Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 A0127_00720 686033a1dbd75a5998421c03bbc25337 309 Gene3D G3DSA:3.30.70.3130 1 101 1.3E-34 T 23-10-2018 A0127_00720 686033a1dbd75a5998421c03bbc25337 309 Pfam PF01189 16S rRNA methyltransferase RsmB/F 106 307 9.2E-59 T 23-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 A0127_00720 686033a1dbd75a5998421c03bbc25337 309 SUPERFAMILY SSF53335 8 308 1.53E-76 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A0127_04110 51b7df3c22de8ddf68482f768364cdf8 397 TIGRFAM TIGR01242 26Sp45: 26S proteasome subunit P45 family 20 379 3.7E-200 T 23-10-2018 IPR005937 26S proteasome regulatory subunit P45-like GO:0005737|GO:0016787|GO:0030163 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 A0127_04110 51b7df3c22de8ddf68482f768364cdf8 397 ProSitePatterns PS00674 AAA-protein family signature. 278 296 - T 23-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 A0127_04110 51b7df3c22de8ddf68482f768364cdf8 397 Pfam PF16450 Proteasomal ATPase OB/ID domain 65 121 2.1E-7 T 23-10-2018 IPR032501 Proteasomal ATPase, OB/ID domain A0127_04110 51b7df3c22de8ddf68482f768364cdf8 397 Gene3D G3DSA:1.10.8.60 309 380 6.4E-29 T 23-10-2018 A0127_04110 51b7df3c22de8ddf68482f768364cdf8 397 SMART SM00382 171 310 3.6E-24 T 23-10-2018 IPR003593 AAA+ ATPase domain A0127_04110 51b7df3c22de8ddf68482f768364cdf8 397 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 175 308 3.1E-44 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A0127_04110 51b7df3c22de8ddf68482f768364cdf8 397 SUPERFAMILY SSF52540 133 382 2.76E-72 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_04110 51b7df3c22de8ddf68482f768364cdf8 397 Gene3D G3DSA:2.40.50.140 24 127 1.0E-27 T 23-10-2018 A0127_04110 51b7df3c22de8ddf68482f768364cdf8 397 Hamap MF_00553 Proteasome-activating nucleotidase [pan]. 4 396 47.696 T 23-10-2018 IPR023501 Proteasome-activating nucleotidase PAN A0127_04110 51b7df3c22de8ddf68482f768364cdf8 397 Gene3D G3DSA:3.40.50.300 128 308 7.5E-72 T 23-10-2018 A0127_00105 05b9ae637ec7f4fe81850fca5a43411c 308 Gene3D G3DSA:3.90.25.10 169 302 8.9E-108 T 23-10-2018 A0127_00105 05b9ae637ec7f4fe81850fca5a43411c 308 Gene3D G3DSA:3.40.50.720 9 290 8.9E-108 T 23-10-2018 A0127_00105 05b9ae637ec7f4fe81850fca5a43411c 308 Pfam PF01370 NAD dependent epimerase/dehydratase family 7 237 5.0E-63 T 23-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 A0127_00105 05b9ae637ec7f4fe81850fca5a43411c 308 SUPERFAMILY SSF51735 1 306 1.67E-102 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A0127_07580 bd13b56895a5106c823f4a51a725e804 155 Gene3D G3DSA:1.10.15.30 60 114 9.5E-55 T 23-10-2018 IPR023106 Ribosomal protein L30, central domain, archaeal type A0127_07580 bd13b56895a5106c823f4a51a725e804 155 SUPERFAMILY SSF55129 5 155 1.83E-49 T 23-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily A0127_07580 bd13b56895a5106c823f4a51a725e804 155 TIGRFAM TIGR01309 uL30_arch: ribosomal protein uL30 4 155 1.3E-61 T 23-10-2018 IPR005997 Ribosomal protein L30, archaeal GO:0003735|GO:0006412|GO:0015934 A0127_07580 bd13b56895a5106c823f4a51a725e804 155 Pfam PF00327 Ribosomal protein L30p/L7e 6 54 1.5E-16 T 23-10-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain A0127_07580 bd13b56895a5106c823f4a51a725e804 155 Hamap MF_01371_A 50S ribosomal protein L30 [rpmD]. 1 155 81.223 T 23-10-2018 IPR005997 Ribosomal protein L30, archaeal GO:0003735|GO:0006412|GO:0015934 A0127_07580 bd13b56895a5106c823f4a51a725e804 155 ProSitePatterns PS00634 Ribosomal protein L30 signature. 22 54 - T 23-10-2018 IPR018038 Ribosomal protein L30, conserved site A0127_07580 bd13b56895a5106c823f4a51a725e804 155 Gene3D G3DSA:3.30.1390.20 5 143 9.5E-55 T 23-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily A0127_07375 21e7967c58f2626ed8ea83856548a637 380 Pfam PF00999 Sodium/hydrogen exchanger family 9 376 9.8E-65 T 23-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 A0127_07375 21e7967c58f2626ed8ea83856548a637 380 Gene3D G3DSA:1.20.1530.20 1 380 9.3E-98 T 23-10-2018 IPR038770 Sodium/solute symporter superfamily A0127_03120 3010262ce261814837a5f6a5b2c8864a 100 Gene3D G3DSA:3.30.70.930 1 97 5.5E-36 T 23-10-2018 IPR029756 MTH1187/YkoF-like A0127_03120 3010262ce261814837a5f6a5b2c8864a 100 SUPERFAMILY SSF89957 1 96 1.57E-31 T 23-10-2018 IPR029756 MTH1187/YkoF-like A0127_03120 3010262ce261814837a5f6a5b2c8864a 100 TIGRFAM TIGR00106 TIGR00106: uncharacterized protein, MTH1187 family 2 97 4.2E-31 T 23-10-2018 IPR002767 Thiamine-binding protein A0127_03120 3010262ce261814837a5f6a5b2c8864a 100 Pfam PF01910 Thiamine-binding protein 4 93 1.4E-33 T 23-10-2018 IPR002767 Thiamine-binding protein A0127_09540 d4879ae056d42111c34e49d23ae2df4f 241 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A0127_09540 d4879ae056d42111c34e49d23ae2df4f 241 Gene3D G3DSA:3.40.50.300 1 228 3.9E-51 T 23-10-2018 A0127_09540 d4879ae056d42111c34e49d23ae2df4f 241 SMART SM00382 26 208 1.9E-4 T 23-10-2018 IPR003593 AAA+ ATPase domain A0127_09540 d4879ae056d42111c34e49d23ae2df4f 241 SUPERFAMILY SSF52540 2 222 4.0E-49 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_09540 d4879ae056d42111c34e49d23ae2df4f 241 Pfam PF00005 ABC transporter 18 160 1.9E-28 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A0127_00215 3c0a9ba2b52512c0fcaaf9c2f5383632 85 SUPERFAMILY SSF143430 1 71 6.02E-23 T 23-10-2018 A0127_00215 3c0a9ba2b52512c0fcaaf9c2f5383632 85 Pfam PF09827 CRISPR associated protein Cas2 1 67 1.4E-20 T 23-10-2018 IPR019199 Virulence-associated protein D / CRISPR associated protein Cas2 A0127_00215 3c0a9ba2b52512c0fcaaf9c2f5383632 85 TIGRFAM TIGR01573 cas2: CRISPR-associated endonuclease Cas2 1 69 2.6E-14 T 23-10-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 A0127_00215 3c0a9ba2b52512c0fcaaf9c2f5383632 85 Gene3D G3DSA:3.30.70.240 1 64 1.4E-27 T 23-10-2018 A0127_00215 3c0a9ba2b52512c0fcaaf9c2f5383632 85 Hamap MF_01471 CRISPR-associated endoribonuclease Cas2 [cas2]. 1 85 14.079 T 23-10-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 A0127_00580 d066ef24a73b2bbe708c5825ff6fb1c2 98 Gene3D G3DSA:2.30.30.70 2 97 1.0E-36 T 23-10-2018 IPR036948 Ribosomal protein L21 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_00580 d066ef24a73b2bbe708c5825ff6fb1c2 98 Pfam PF01157 Ribosomal protein L21e 6 96 1.1E-32 T 23-10-2018 IPR001147 Ribosomal protein L21e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_00580 d066ef24a73b2bbe708c5825ff6fb1c2 98 SUPERFAMILY SSF50104 6 97 7.22E-32 T 23-10-2018 IPR008991 Translation protein SH3-like domain superfamily A0127_00580 d066ef24a73b2bbe708c5825ff6fb1c2 98 ProSitePatterns PS01171 Ribosomal protein L21e signature. 38 63 - T 23-10-2018 IPR018259 Ribosomal protein L21e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_00580 d066ef24a73b2bbe708c5825ff6fb1c2 98 Hamap MF_00369 50S ribosomal protein L21e [rpl21e]. 3 97 30.414 T 23-10-2018 IPR022856 Ribosomal protein L21e, archaeal A0127_03905 5cc51c31fd4fabe8d8ba573817180a3f 222 Pfam PF03673 Uncharacterised protein family (UPF0128) 1 222 1.5E-107 T 23-10-2018 IPR005266 Uncharacterised protein family UPF0128 A0127_03905 5cc51c31fd4fabe8d8ba573817180a3f 222 Hamap MF_00264 UPF0128 protein . 1 222 138.237 T 23-10-2018 IPR005266 Uncharacterised protein family UPF0128 A0127_03905 5cc51c31fd4fabe8d8ba573817180a3f 222 ProDom PD023377 UPF0128 PYRAB08320 PH1314 PF1488 MJ1463 AQ_756 1 222 1.0E-116 T 23-10-2018 IPR005266 Uncharacterised protein family UPF0128 A0127_03905 5cc51c31fd4fabe8d8ba573817180a3f 222 TIGRFAM TIGR00703 TIGR00703: TIGR00703 family protein 1 222 8.0E-99 T 23-10-2018 IPR005266 Uncharacterised protein family UPF0128 A0127_00555 2901f583c7fa1d22b20c5f6382dd8dba 440 SUPERFAMILY SSF53774 90 437 3.79E-118 T 23-10-2018 IPR036152 Asparaginase/glutaminase-like superfamily Reactome: R-HSA-70614 A0127_00555 2901f583c7fa1d22b20c5f6382dd8dba 440 Pfam PF00710 Asparaginase, N-terminal 96 289 7.4E-61 T 23-10-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 A0127_00555 2901f583c7fa1d22b20c5f6382dd8dba 440 PRINTS PR00139 Asparaginase/glutaminase family signature 355 373 4.9E-19 T 23-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 A0127_00555 2901f583c7fa1d22b20c5f6382dd8dba 440 PRINTS PR00139 Asparaginase/glutaminase family signature 172 190 4.9E-19 T 23-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 A0127_00555 2901f583c7fa1d22b20c5f6382dd8dba 440 PRINTS PR00139 Asparaginase/glutaminase family signature 96 107 4.9E-19 T 23-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 A0127_00555 2901f583c7fa1d22b20c5f6382dd8dba 440 Hamap MF_00586 Glutamyl-tRNA(Gln) amidotransferase subunit D [gatD]. 20 434 48.763 T 23-10-2018 IPR011878 Glutamyl-tRNA(Gln) amidotransferase subunit D GO:0006450 A0127_00555 2901f583c7fa1d22b20c5f6382dd8dba 440 ProSitePatterns PS00144 Asparaginase / glutaminase active site signature 1. 98 106 - T 23-10-2018 IPR020827 Asparaginase/glutaminase, active site 1 GO:0006520 A0127_00555 2901f583c7fa1d22b20c5f6382dd8dba 440 PIRSF PIRSF001220 90 429 4.4E-112 T 23-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 A0127_00555 2901f583c7fa1d22b20c5f6382dd8dba 440 SUPERFAMILY SSF141300 5 76 2.49E-20 T 23-10-2018 IPR037222 GatD, N-terminal A0127_00555 2901f583c7fa1d22b20c5f6382dd8dba 440 Gene3D G3DSA:3.40.50.40 303 440 3.4E-57 T 23-10-2018 IPR027473 L-asparaginase, C-terminal Reactome: R-HSA-70614 A0127_00555 2901f583c7fa1d22b20c5f6382dd8dba 440 PIRSF PIRSF500175 14 438 1.8E-187 T 23-10-2018 IPR011878 Glutamyl-tRNA(Gln) amidotransferase subunit D GO:0006450 A0127_00555 2901f583c7fa1d22b20c5f6382dd8dba 440 ProSitePatterns PS00917 Asparaginase / glutaminase active site signature 2. 173 183 - T 23-10-2018 IPR027475 Asparaginase/glutaminase, active site 2 Reactome: R-HSA-70614 A0127_00555 2901f583c7fa1d22b20c5f6382dd8dba 440 Gene3D G3DSA:3.40.50.1170 82 302 2.3E-85 T 23-10-2018 IPR037152 L-asparaginase, N-terminal domain superfamily Reactome: R-HSA-70614 A0127_00555 2901f583c7fa1d22b20c5f6382dd8dba 440 TIGRFAM TIGR00519 asnASE_I: L-asparaginase, type I 93 430 5.6E-145 T 23-10-2018 IPR006033 L-asparaginase, type I GO:0004067|GO:0006520 Reactome: R-HSA-70614 A0127_00555 2901f583c7fa1d22b20c5f6382dd8dba 440 Gene3D G3DSA:2.30.30.520 3 80 3.0E-22 T 23-10-2018 IPR037222 GatD, N-terminal A0127_00555 2901f583c7fa1d22b20c5f6382dd8dba 440 SMART SM00870 95 418 5.7E-154 T 23-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 A0127_00555 2901f583c7fa1d22b20c5f6382dd8dba 440 TIGRFAM TIGR02153 gatD_arch: glutamyl-tRNA(Gln) amidotransferase, subunit D 32 434 3.8E-196 T 23-10-2018 IPR011878 Glutamyl-tRNA(Gln) amidotransferase subunit D GO:0006450 A0127_02000 9e8d310042a2835d1ab6413f24a4dbfa 483 SUPERFAMILY SSF52317 192 389 1.36E-29 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A0127_02000 9e8d310042a2835d1ab6413f24a4dbfa 483 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 5 230 2.4E-21 T 23-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain A0127_02000 9e8d310042a2835d1ab6413f24a4dbfa 483 Gene3D G3DSA:3.40.50.880 250 400 4.1E-16 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A0127_02000 9e8d310042a2835d1ab6413f24a4dbfa 483 SUPERFAMILY SSF52540 1 232 2.46E-51 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_02000 9e8d310042a2835d1ab6413f24a4dbfa 483 Hamap MF_00028 Cobyric acid synthase [cobQ]. 1 483 165.728 T 23-10-2018 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 A0127_02000 9e8d310042a2835d1ab6413f24a4dbfa 483 Gene3D G3DSA:3.40.50.300 4 249 4.3E-51 T 23-10-2018 A0127_02000 9e8d310042a2835d1ab6413f24a4dbfa 483 TIGRFAM TIGR00313 cobQ: cobyric acid synthase CobQ 5 476 1.6E-160 T 23-10-2018 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 A0127_02000 9e8d310042a2835d1ab6413f24a4dbfa 483 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 250 432 4.2E-50 T 23-10-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 A0127_09325 f4c194ce5f0bc264853f74c43bbd1b83 394 Gene3D G3DSA:3.40.50.360 244 387 9.2E-22 T 23-10-2018 IPR029039 Flavoprotein-like superfamily A0127_09325 f4c194ce5f0bc264853f74c43bbd1b83 394 PIRSF PIRSF005243 1 392 1.9E-127 T 23-10-2018 IPR016440 Rubredoxin-oxygen oxidoreductase GO:0009055|GO:0010181|GO:0016491|GO:0046872 A0127_09325 f4c194ce5f0bc264853f74c43bbd1b83 394 SMART SM00849 34 222 3.1E-33 T 23-10-2018 IPR001279 Metallo-beta-lactamase A0127_09325 f4c194ce5f0bc264853f74c43bbd1b83 394 Gene3D G3DSA:3.60.15.10 1 241 3.6E-92 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A0127_09325 f4c194ce5f0bc264853f74c43bbd1b83 394 SUPERFAMILY SSF52218 245 387 8.25E-26 T 23-10-2018 IPR029039 Flavoprotein-like superfamily A0127_09325 f4c194ce5f0bc264853f74c43bbd1b83 394 Pfam PF00753 Metallo-beta-lactamase superfamily 35 170 1.4E-9 T 23-10-2018 IPR001279 Metallo-beta-lactamase A0127_09325 f4c194ce5f0bc264853f74c43bbd1b83 394 SUPERFAMILY SSF56281 3 275 3.41E-57 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A0127_01870 db0aa2f4ecbb67855b3b141cc18fdfa6 375 Gene3D G3DSA:3.40.50.620 1 226 7.1E-61 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A0127_01870 db0aa2f4ecbb67855b3b141cc18fdfa6 375 SUPERFAMILY SSF52374 2 363 3.05E-66 T 23-10-2018 A0127_01870 db0aa2f4ecbb67855b3b141cc18fdfa6 375 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 3 360 3.6E-34 T 23-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 A0127_01870 db0aa2f4ecbb67855b3b141cc18fdfa6 375 Gene3D G3DSA:1.10.240.10 227 375 2.9E-56 T 23-10-2018 A0127_01870 db0aa2f4ecbb67855b3b141cc18fdfa6 375 Hamap MF_02009 Tyrosine--tRNA ligase [tyrS]. 5 359 47.987 T 23-10-2018 IPR023678 Tyrosine-tRNA ligase, type 4 GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 A0127_01870 db0aa2f4ecbb67855b3b141cc18fdfa6 375 PIRSF PIRSF006588 1 375 6.4E-132 T 23-10-2018 IPR023617 Tyrosine-tRNA ligase, archaeal/eukaryotic-type GO:0004831 KEGG: 00970+6.1.1.1 A0127_01870 db0aa2f4ecbb67855b3b141cc18fdfa6 375 Pfam PF00579 tRNA synthetases class I (W and Y) 33 352 2.1E-44 T 23-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 A0127_05450 d3b2165bed7f808472df4865055aa925 184 Pfam PF01725 Ham1 family 3 178 4.4E-52 T 23-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 A0127_05450 d3b2165bed7f808472df4865055aa925 184 SUPERFAMILY SSF52972 1 182 2.88E-64 T 23-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like A0127_05450 d3b2165bed7f808472df4865055aa925 184 Gene3D G3DSA:3.90.950.10 1 184 3.0E-74 T 23-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like A0127_05450 d3b2165bed7f808472df4865055aa925 184 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 3 179 8.3E-65 T 23-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 A0127_05450 d3b2165bed7f808472df4865055aa925 184 Hamap MF_01405 dITP/XTP pyrophosphatase. 1 181 43.153 T 23-10-2018 IPR020922 dITP/XTP pyrophosphatase GO:0009143|GO:0017111 KEGG: 00230+3.6.1.66 A0127_02290 f8e6f0bff65a75b7d49c5927b3d7833f 350 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 3 154 1.4E-15 T 23-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain A0127_02290 f8e6f0bff65a75b7d49c5927b3d7833f 350 Gene3D G3DSA:3.10.50.80 3 166 1.9E-51 T 23-10-2018 A0127_02290 f8e6f0bff65a75b7d49c5927b3d7833f 350 SUPERFAMILY SSF54534 3 156 2.36E-40 T 23-10-2018 A0127_02325 45c2141a3db655bb2074f4189d71a21f 1222 Gene3D G3DSA:1.10.460.10 826 1213 8.4E-146 T 23-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 A0127_02325 45c2141a3db655bb2074f4189d71a21f 1222 SUPERFAMILY SSF52540 2 240 8.58E-35 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_02325 45c2141a3db655bb2074f4189d71a21f 1222 TIGRFAM TIGR01054 rgy: reverse gyrase 2 1217 0.0 T 23-10-2018 IPR005736 Reverse gyrase GO:0003677|GO:0003916|GO:0006265 A0127_02325 45c2141a3db655bb2074f4189d71a21f 1222 Gene3D G3DSA:3.40.50.300 546 629 2.2E-14 T 23-10-2018 A0127_02325 45c2141a3db655bb2074f4189d71a21f 1222 Gene3D G3DSA:3.40.50.300 320 503 5.5E-34 T 23-10-2018 A0127_02325 45c2141a3db655bb2074f4189d71a21f 1222 SMART SM00493 642 795 2.4E-43 T 23-10-2018 IPR006171 TOPRIM domain A0127_02325 45c2141a3db655bb2074f4189d71a21f 1222 Pfam PF00270 DEAD/DEAH box helicase 88 223 4.7E-12 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A0127_02325 45c2141a3db655bb2074f4189d71a21f 1222 SMART SM00437 916 1172 8.8E-101 T 23-10-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 A0127_02325 45c2141a3db655bb2074f4189d71a21f 1222 Pfam PF01751 Toprim domain 644 805 1.8E-27 T 23-10-2018 IPR006171 TOPRIM domain A0127_02325 45c2141a3db655bb2074f4189d71a21f 1222 Gene3D G3DSA:3.40.50.140 640 825 6.6E-30 T 23-10-2018 A0127_02325 45c2141a3db655bb2074f4189d71a21f 1222 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 769 782 1.7E-28 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A0127_02325 45c2141a3db655bb2074f4189d71a21f 1222 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 958 967 1.7E-28 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A0127_02325 45c2141a3db655bb2074f4189d71a21f 1222 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 1039 1055 1.7E-28 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A0127_02325 45c2141a3db655bb2074f4189d71a21f 1222 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 1133 1147 1.7E-28 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A0127_02325 45c2141a3db655bb2074f4189d71a21f 1222 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 855 873 1.7E-28 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A0127_02325 45c2141a3db655bb2074f4189d71a21f 1222 SUPERFAMILY SSF56712 638 1218 9.68E-144 T 23-10-2018 IPR023405 DNA topoisomerase, type IA, core domain A0127_02325 45c2141a3db655bb2074f4189d71a21f 1222 Hamap MF_01125 Reverse gyrase [rgy]. 1 1220 66.118 T 23-10-2018 IPR005736 Reverse gyrase GO:0003677|GO:0003916|GO:0006265 A0127_02325 45c2141a3db655bb2074f4189d71a21f 1222 Gene3D G3DSA:2.60.510.20 877 1117 8.4E-146 T 23-10-2018 A0127_02325 45c2141a3db655bb2074f4189d71a21f 1222 Gene3D G3DSA:1.10.290.10 926 1050 8.4E-146 T 23-10-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 A0127_02325 45c2141a3db655bb2074f4189d71a21f 1222 SMART SM00436 796 883 1.9E-42 T 23-10-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 A0127_02325 45c2141a3db655bb2074f4189d71a21f 1222 SUPERFAMILY SSF52540 326 625 1.71E-39 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_02325 45c2141a3db655bb2074f4189d71a21f 1222 Pfam PF01131 DNA topoisomerase 820 1209 3.1E-84 T 23-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 A0127_02325 45c2141a3db655bb2074f4189d71a21f 1222 SMART SM00487 81 331 7.0E-23 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A0127_00075 02678583729bb4d522603acdc1cf3f40 919 Pfam PF08494 DEAD/H associated 583 750 9.7E-16 T 23-10-2018 IPR013701 DEAD/H associated GO:0005524|GO:0016818 A0127_00075 02678583729bb4d522603acdc1cf3f40 919 Gene3D G3DSA:3.40.50.300 202 370 2.3E-31 T 23-10-2018 A0127_00075 02678583729bb4d522603acdc1cf3f40 919 Pfam PF00270 DEAD/DEAH box helicase 18 182 1.6E-27 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A0127_00075 02678583729bb4d522603acdc1cf3f40 919 PIRSF PIRSF037307 1 912 0.0 T 23-10-2018 IPR017170 Lhr-like ATP-dependent RNA helicase, predicted GO:0005524|GO:0016818 A0127_00075 02678583729bb4d522603acdc1cf3f40 919 SMART SM00490 259 341 1.4E-24 T 23-10-2018 IPR001650 Helicase, C-terminal A0127_00075 02678583729bb4d522603acdc1cf3f40 919 SUPERFAMILY SSF52540 28 350 1.07E-52 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_00075 02678583729bb4d522603acdc1cf3f40 919 Gene3D G3DSA:3.40.50.300 4 201 3.8E-46 T 23-10-2018 A0127_00075 02678583729bb4d522603acdc1cf3f40 919 Pfam PF00271 Helicase conserved C-terminal domain 237 336 9.1E-19 T 23-10-2018 IPR001650 Helicase, C-terminal A0127_00075 02678583729bb4d522603acdc1cf3f40 919 SMART SM00487 12 210 2.2E-35 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A0127_08170 5e40f58fd2034de823de284129ffe13f 418 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 9 302 8.9E-31 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A0127_08170 5e40f58fd2034de823de284129ffe13f 418 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 281 303 1.3E-25 T 23-10-2018 A0127_08170 5e40f58fd2034de823de284129ffe13f 418 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 11 30 1.3E-25 T 23-10-2018 A0127_08170 5e40f58fd2034de823de284129ffe13f 418 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 253 269 1.3E-25 T 23-10-2018 A0127_08170 5e40f58fd2034de823de284129ffe13f 418 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 116 134 1.3E-25 T 23-10-2018 A0127_08170 5e40f58fd2034de823de284129ffe13f 418 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 163 181 1.3E-25 T 23-10-2018 A0127_08170 5e40f58fd2034de823de284129ffe13f 418 Gene3D G3DSA:3.50.50.60 9 302 1.1E-53 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A0127_08170 5e40f58fd2034de823de284129ffe13f 418 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 291 309 5.9E-20 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A0127_08170 5e40f58fd2034de823de284129ffe13f 418 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 211 227 5.9E-20 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A0127_08170 5e40f58fd2034de823de284129ffe13f 418 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 10 32 5.9E-20 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A0127_08170 5e40f58fd2034de823de284129ffe13f 418 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 117 125 5.9E-20 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A0127_08170 5e40f58fd2034de823de284129ffe13f 418 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 159 183 5.9E-20 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A0127_08170 5e40f58fd2034de823de284129ffe13f 418 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 66 76 5.9E-20 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A0127_08170 5e40f58fd2034de823de284129ffe13f 418 Gene3D G3DSA:3.50.50.60 128 261 1.1E-53 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A0127_08170 5e40f58fd2034de823de284129ffe13f 418 SUPERFAMILY SSF51905 9 326 1.21E-42 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A0127_09405 257103c44c7d831f0108b01d9156ce2d 165 PIRSF PIRSF019239 1 165 1.0E-39 T 23-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 A0127_09405 257103c44c7d831f0108b01d9156ce2d 165 Pfam PF01899 Na+/H+ ion antiporter subunit 10 163 9.9E-38 T 23-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 A0127_09805 227b6a70009e0650ec1fd0f2c25e9944 82 Hamap MF_00025 DNA-directed RNA polymerase subunit H [rpoH]. 7 80 23.904 T 23-10-2018 IPR020609 Archaeal RpoH /eukaryotic RPB5 RNA polymerase subunit GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A0127_09805 227b6a70009e0650ec1fd0f2c25e9944 82 SUPERFAMILY SSF55287 7 80 7.06E-29 T 23-10-2018 IPR035913 RPB5-like RNA polymerase subunit superfamily Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A0127_09805 227b6a70009e0650ec1fd0f2c25e9944 82 ProSitePatterns PS01110 RNA polymerases H / 23 Kd subunits signature. 12 25 - T 23-10-2018 IPR020608 RNA polymerase, subunit H/Rpb5, conserved site Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A0127_09805 227b6a70009e0650ec1fd0f2c25e9944 82 Gene3D G3DSA:3.90.940.20 1 82 2.0E-37 T 23-10-2018 IPR035913 RPB5-like RNA polymerase subunit superfamily Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A0127_09805 227b6a70009e0650ec1fd0f2c25e9944 82 ProDom PD005155 RNA POLYMERASE DNA-DIRECTED SUBUNIT NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION II H POLYPEPTIDE 37 79 1.0E-17 T 23-10-2018 IPR000783 RNA polymerase, subunit H/Rpb5 C-terminal GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A0127_09805 227b6a70009e0650ec1fd0f2c25e9944 82 Pfam PF01191 RNA polymerase Rpb5, C-terminal domain 7 79 7.9E-33 T 23-10-2018 IPR000783 RNA polymerase, subunit H/Rpb5 C-terminal GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A0127_01480 1be8a6059b74785c4cc08e58b9da4bef 97 Gene3D G3DSA:1.10.287.1080 1 79 4.0E-28 T 23-10-2018 A0127_01480 1be8a6059b74785c4cc08e58b9da4bef 97 SUPERFAMILY SSF101386 2 79 6.71E-21 T 23-10-2018 A0127_01480 1be8a6059b74785c4cc08e58b9da4bef 97 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 23 82 1.8E-14 T 23-10-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core A0127_03080 d1af9aa60b82e96170e45d4ecc3e52ca 222 Gene3D G3DSA:3.60.160.10 1 222 1.0E-81 T 23-10-2018 IPR036983 Mitochondrial biogenesis AIM24 superfamily A0127_03080 d1af9aa60b82e96170e45d4ecc3e52ca 222 TIGRFAM TIGR00266 TIGR00266: TIGR00266 family protein 1 220 9.3E-85 T 23-10-2018 IPR002838 Mitochondrial biogenesis protein AIM24 A0127_03080 d1af9aa60b82e96170e45d4ecc3e52ca 222 Pfam PF01987 Mitochondrial biogenesis AIM24 3 205 6.6E-63 T 23-10-2018 IPR002838 Mitochondrial biogenesis protein AIM24 A0127_03080 d1af9aa60b82e96170e45d4ecc3e52ca 222 SUPERFAMILY SSF51219 1 221 7.32E-74 T 23-10-2018 IPR016031 Tryptophan RNA-binding attenuator protein-like domain superfamily A0127_08555 92a97e869876bacb08819cb531f63a56 214 SUPERFAMILY SSF52402 3 210 1.96E-52 T 23-10-2018 A0127_08555 92a97e869876bacb08819cb531f63a56 214 Gene3D G3DSA:3.90.1490.10 118 212 1.3E-13 T 23-10-2018 A0127_08555 92a97e869876bacb08819cb531f63a56 214 Gene3D G3DSA:3.40.50.620 2 117 3.6E-12 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A0127_08555 92a97e869876bacb08819cb531f63a56 214 Pfam PF01902 Diphthamide synthase 3 212 2.8E-38 T 23-10-2018 IPR002761 Diphthamide synthase domain MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 A0127_08555 92a97e869876bacb08819cb531f63a56 214 TIGRFAM TIGR00290 MJ0570_dom: MJ0570-related uncharacterized domain 3 210 1.5E-35 T 23-10-2018 IPR002761 Diphthamide synthase domain MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 A0127_03475 b1e4218388639edd4ad15dbc5720381e 333 SUPERFAMILY SSF161098 95 320 1.05E-19 T 23-10-2018 IPR035906 MetI-like superfamily A0127_03475 b1e4218388639edd4ad15dbc5720381e 333 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 116 333 9.0E-44 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A0127_03475 b1e4218388639edd4ad15dbc5720381e 333 Gene3D G3DSA:1.10.3720.10 94 327 7.0E-25 T 23-10-2018 IPR035906 MetI-like superfamily A0127_04880 ec4f0552cff465f3baa83b74e2b00753 83 Gene3D G3DSA:1.20.1440.50 1 83 8.5E-31 T 23-10-2018 IPR023130 Ta0600-like superfamily A0127_04880 ec4f0552cff465f3baa83b74e2b00753 83 ProDom PD029943 UPF0147 ARCHAEAL PF0239 ST0460.1 MM1385 CYTOSOLIC SACI_0891 TV0625 APES069 TA0600 1 83 3.0E-40 T 23-10-2018 IPR005354 Uncharacterised protein family UPF0147 A0127_04880 ec4f0552cff465f3baa83b74e2b00753 83 SUPERFAMILY SSF158436 3 83 5.36E-30 T 23-10-2018 A0127_04880 ec4f0552cff465f3baa83b74e2b00753 83 Hamap MF_00342 UPF0147 protein . 1 83 29.41 T 23-10-2018 IPR005354 Uncharacterised protein family UPF0147 A0127_04880 ec4f0552cff465f3baa83b74e2b00753 83 Pfam PF03685 Uncharacterised protein family (UPF0147) 2 82 5.9E-33 T 23-10-2018 IPR005354 Uncharacterised protein family UPF0147 A0127_01125 c83e013eb34708c132a246b1ed0dfaa2 267 Gene3D G3DSA:3.10.270.10 1 266 1.1E-66 T 23-10-2018 A0127_01125 c83e013eb34708c132a246b1ed0dfaa2 267 Pfam PF02649 Type I GTP cyclohydrolase folE2 4 263 3.5E-65 T 23-10-2018 IPR003801 GTP cyclohydrolase FolE2/MptA GO:0003933 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852 A0127_00770 44f697cb99ec7739a16656c67a442543 207 Gene3D G3DSA:3.40.1550.10 9 203 5.5E-53 T 23-10-2018 IPR028976 CheC-like superfamily A0127_00770 44f697cb99ec7739a16656c67a442543 207 Pfam PF04509 CheC-like family 110 145 7.0E-9 T 23-10-2018 IPR007597 CheC-like protein GO:0016787 A0127_00770 44f697cb99ec7739a16656c67a442543 207 Pfam PF04509 CheC-like family 15 48 3.3E-4 T 23-10-2018 IPR007597 CheC-like protein GO:0016787 A0127_00770 44f697cb99ec7739a16656c67a442543 207 SUPERFAMILY SSF103039 9 202 1.19E-46 T 23-10-2018 IPR028976 CheC-like superfamily A0127_08315 29176868e2e50b8f3621200e2b329033 793 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 19 350 6.8E-119 T 23-10-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 A0127_08315 29176868e2e50b8f3621200e2b329033 793 PIRSF PIRSF000854 1 777 3.0E-206 T 23-10-2018 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484|MetaCyc: PWY-6142 A0127_08315 29176868e2e50b8f3621200e2b329033 793 Gene3D G3DSA:3.30.1490.20 3 197 1.1E-72 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 A0127_08315 29176868e2e50b8f3621200e2b329033 793 Gene3D G3DSA:3.30.470.20 198 353 5.5E-54 T 23-10-2018 A0127_08315 29176868e2e50b8f3621200e2b329033 793 Gene3D G3DSA:3.50.30.10 354 462 3.7E-43 T 23-10-2018 A0127_08315 29176868e2e50b8f3621200e2b329033 793 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 678 696 - T 23-10-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 A0127_08315 29176868e2e50b8f3621200e2b329033 793 Gene3D G3DSA:3.20.20.60 463 791 5.2E-105 T 23-10-2018 A0127_08315 29176868e2e50b8f3621200e2b329033 793 TIGRFAM TIGR01418 PEP_synth: phosphoenolpyruvate synthase 7 773 2.0E-289 T 23-10-2018 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484|MetaCyc: PWY-6142 A0127_08315 29176868e2e50b8f3621200e2b329033 793 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 484 772 5.6E-98 T 23-10-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 A0127_08315 29176868e2e50b8f3621200e2b329033 793 SUPERFAMILY SSF56059 4 381 1.14E-106 T 23-10-2018 A0127_08315 29176868e2e50b8f3621200e2b329033 793 Pfam PF00391 PEP-utilising enzyme, mobile domain 381 453 8.1E-29 T 23-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 A0127_08315 29176868e2e50b8f3621200e2b329033 793 SUPERFAMILY SSF52009 353 461 3.92E-37 T 23-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 A0127_08315 29176868e2e50b8f3621200e2b329033 793 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 695 710 8.0E-14 T 23-10-2018 A0127_08315 29176868e2e50b8f3621200e2b329033 793 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 514 533 8.0E-14 T 23-10-2018 A0127_08315 29176868e2e50b8f3621200e2b329033 793 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 678 693 8.0E-14 T 23-10-2018 A0127_08315 29176868e2e50b8f3621200e2b329033 793 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 731 743 8.0E-14 T 23-10-2018 A0127_08315 29176868e2e50b8f3621200e2b329033 793 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 412 423 - T 23-10-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 A0127_08315 29176868e2e50b8f3621200e2b329033 793 SUPERFAMILY SSF51621 487 780 1.02E-95 T 23-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 A0127_08305 3c5f24621d2385af1f2d09d431d65c9e 202 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 4 50 5.4E-14 T 23-10-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 A0127_08305 3c5f24621d2385af1f2d09d431d65c9e 202 ProSitePatterns PS00397 Site-specific recombinases active site. 60 68 - T 23-10-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 A0127_08305 3c5f24621d2385af1f2d09d431d65c9e 202 Pfam PF00239 Resolvase, N terminal domain 57 189 8.0E-26 T 23-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 A0127_08305 3c5f24621d2385af1f2d09d431d65c9e 202 SUPERFAMILY SSF53041 56 188 6.15E-26 T 23-10-2018 IPR036162 Resolvase-like, N-terminal catalytic domain superfamily GO:0000150|GO:0003677|GO:0006310 A0127_08305 3c5f24621d2385af1f2d09d431d65c9e 202 SMART SM00857 57 180 2.1E-27 T 23-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 A0127_08305 3c5f24621d2385af1f2d09d431d65c9e 202 Pfam PF12728 Helix-turn-helix domain 3 51 3.7E-14 T 23-10-2018 A0127_08305 3c5f24621d2385af1f2d09d431d65c9e 202 Gene3D G3DSA:1.10.1660.10 3 52 1.6E-6 T 23-10-2018 A0127_08305 3c5f24621d2385af1f2d09d431d65c9e 202 SUPERFAMILY SSF46955 2 50 1.25E-5 T 23-10-2018 IPR009061 Putative DNA-binding domain superfamily A0127_08305 3c5f24621d2385af1f2d09d431d65c9e 202 Gene3D G3DSA:3.40.50.1390 53 154 1.3E-28 T 23-10-2018 A0127_09355 330277a88bec38308c3176f30bc6f8ff 230 SUPERFAMILY SSF53335 2 224 6.33E-40 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A0127_09355 330277a88bec38308c3176f30bc6f8ff 230 TIGRFAM TIGR01934 MenG_MenH_UbiE: ubiquinone/menaquinone biosynthesis methyltransferase 2 225 3.2E-65 T 23-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 A0127_09355 330277a88bec38308c3176f30bc6f8ff 230 Hamap MF_01813 Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE [ubiE]. 1 228 30.54 T 23-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 A0127_09355 330277a88bec38308c3176f30bc6f8ff 230 ProSitePatterns PS01184 ubiE/COQ5 methyltransferase family signature 2. 137 151 - T 23-10-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 A0127_09355 330277a88bec38308c3176f30bc6f8ff 230 Gene3D G3DSA:3.40.50.150 8 228 7.1E-56 T 23-10-2018 A0127_09355 330277a88bec38308c3176f30bc6f8ff 230 ProSitePatterns PS01183 ubiE/COQ5 methyltransferase family signature 1. 13 28 - T 23-10-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 A0127_09355 330277a88bec38308c3176f30bc6f8ff 230 Pfam PF01209 ubiE/COQ5 methyltransferase family 2 212 1.1E-50 T 23-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 A0127_01165 881f29339fba4e76dd3c3b2c1d7cdce8 637 SUPERFAMILY SSF52540 28 618 4.78E-5 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_01165 881f29339fba4e76dd3c3b2c1d7cdce8 637 SMART SM00488 1 268 2.4E-74 T 23-10-2018 IPR006554 Helicase-like, DEXD box c2 type GO:0004003|GO:0016818 A0127_01165 881f29339fba4e76dd3c3b2c1d7cdce8 637 Pfam PF06733 DEAD_2 62 233 1.1E-33 T 23-10-2018 IPR010614 DEAD2 GO:0003677|GO:0004003|GO:0005524 A0127_01165 881f29339fba4e76dd3c3b2c1d7cdce8 637 Gene3D G3DSA:1.10.30.20 93 169 1.2E-115 T 23-10-2018 A0127_01165 881f29339fba4e76dd3c3b2c1d7cdce8 637 SMART SM00487 6 277 5.3E-7 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A0127_01165 881f29339fba4e76dd3c3b2c1d7cdce8 637 SUPERFAMILY SSF52540 4 226 7.68E-17 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_01165 881f29339fba4e76dd3c3b2c1d7cdce8 637 Gene3D G3DSA:1.10.275.40 228 365 1.2E-115 T 23-10-2018 A0127_01165 881f29339fba4e76dd3c3b2c1d7cdce8 637 Pfam PF13307 Helicase C-terminal domain 442 615 2.3E-37 T 23-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 A0127_01165 881f29339fba4e76dd3c3b2c1d7cdce8 637 TIGRFAM TIGR00604 rad3: DNA repair helicase (rad3) 322 626 1.2E-80 T 23-10-2018 IPR013020 ATP-dependent helicase Rad3/Chl1-like GO:0004003 A0127_01165 881f29339fba4e76dd3c3b2c1d7cdce8 637 Gene3D G3DSA:3.40.50.300 412 626 6.4E-43 T 23-10-2018 A0127_01165 881f29339fba4e76dd3c3b2c1d7cdce8 637 SMART SM00491 460 602 2.3E-46 T 23-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 A0127_01165 881f29339fba4e76dd3c3b2c1d7cdce8 637 Pfam PF06777 Helical and beta-bridge domain 238 429 3.0E-64 T 23-10-2018 IPR010643 Helical and beta-bridge domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167246|Reactome: R-HSA-2564830|Reactome: R-HSA-427413|Reactome: R-HSA-5696395|Reactome: R-HSA-5696400|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73863|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-77075 A0127_01165 881f29339fba4e76dd3c3b2c1d7cdce8 637 Gene3D G3DSA:3.40.50.300 18 397 1.2E-115 T 23-10-2018 A0127_08810 af11acb8a760db7bd27e8d293f9c1322 94 Pfam PF13244 Domain of unknown function (DUF4040) 13 79 1.3E-18 T 23-10-2018 IPR025383 Domain of unknown function DUF4040 A0127_07300 b35dfffe6303f15114125b8fb9d4d2e7 251 SUPERFAMILY SSF102705 1 246 2.22E-69 T 23-10-2018 IPR036069 GTP cyclohydrolase 1 type 2/Nif3 superfamily A0127_07300 b35dfffe6303f15114125b8fb9d4d2e7 251 TIGRFAM TIGR00486 YbgI_SA1388: dinuclear metal center protein, YbgI/SA1388 family 2 249 1.8E-60 T 23-10-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 A0127_07300 b35dfffe6303f15114125b8fb9d4d2e7 251 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 6 239 3.9E-56 T 23-10-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 A0127_07300 b35dfffe6303f15114125b8fb9d4d2e7 251 Gene3D G3DSA:3.40.1390.30 97 222 4.1E-75 T 23-10-2018 A0127_07300 b35dfffe6303f15114125b8fb9d4d2e7 251 Gene3D G3DSA:3.40.1390.30 7 239 4.1E-75 T 23-10-2018 A0127_03930 f77b518f75b8ddba3de6ed585efd6aee 67 Gene3D G3DSA:1.10.20.10 1 67 1.5E-22 T 23-10-2018 IPR009072 Histone-fold GO:0046982 A0127_03930 f77b518f75b8ddba3de6ed585efd6aee 67 SUPERFAMILY SSF47113 3 66 4.92E-19 T 23-10-2018 IPR009072 Histone-fold GO:0046982 A0127_03930 f77b518f75b8ddba3de6ed585efd6aee 67 Pfam PF00808 Histone-like transcription factor (CBF/NF-Y) and archaeal histone 2 65 5.3E-20 T 23-10-2018 IPR003958 Transcription factor CBF/NF-Y/archaeal histone domain A0127_03930 f77b518f75b8ddba3de6ed585efd6aee 67 SMART SM00803 12 66 0.0074 T 23-10-2018 IPR004823 TATA box binding protein associated factor (TAF) GO:0006352 A0127_08760 373228185d3eb2e8bfd35de19cf8e6f7 421 PIRSF PIRSF000124 3 409 6.2E-84 T 23-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 A0127_08760 373228185d3eb2e8bfd35de19cf8e6f7 421 Gene3D G3DSA:3.40.50.720 4 199 7.1E-74 T 23-10-2018 A0127_08760 373228185d3eb2e8bfd35de19cf8e6f7 421 SMART SM00984 315 406 1.8E-36 T 23-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A0127_08760 373228185d3eb2e8bfd35de19cf8e6f7 421 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 315 406 1.1E-24 T 23-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A0127_08760 373228185d3eb2e8bfd35de19cf8e6f7 421 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 202 288 3.0E-24 T 23-10-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A0127_08760 373228185d3eb2e8bfd35de19cf8e6f7 421 Gene3D G3DSA:3.40.50.720 233 421 1.5E-68 T 23-10-2018 A0127_08760 373228185d3eb2e8bfd35de19cf8e6f7 421 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 4 184 3.4E-53 T 23-10-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 A0127_08760 373228185d3eb2e8bfd35de19cf8e6f7 421 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 4 401 1.2E-126 T 23-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 A0127_08760 373228185d3eb2e8bfd35de19cf8e6f7 421 SUPERFAMILY SSF48179 202 292 1.39E-27 T 23-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 A0127_08760 373228185d3eb2e8bfd35de19cf8e6f7 421 SUPERFAMILY SSF51735 3 193 6.14E-51 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A0127_08760 373228185d3eb2e8bfd35de19cf8e6f7 421 PIRSF PIRSF500136 1 418 7.0E-146 T 23-10-2018 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 A0127_08760 373228185d3eb2e8bfd35de19cf8e6f7 421 SUPERFAMILY SSF52413 304 406 7.59E-26 T 23-10-2018 IPR036220 UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily Reactome: R-HSA-173599 A0127_03565 013ba2be130f6a7315982e09a585b7d3 215 Gene3D G3DSA:3.90.320.10 5 209 5.6E-24 T 23-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal A0127_03565 013ba2be130f6a7315982e09a585b7d3 215 Pfam PF12705 PD-(D/E)XK nuclease superfamily 79 205 7.8E-6 T 23-10-2018 IPR038726 PD-(D/E)XK endonuclease-like domain, AddAB-type A0127_03565 013ba2be130f6a7315982e09a585b7d3 215 TIGRFAM TIGR00372 cas4: CRISPR-associated protein Cas4 11 207 1.9E-32 T 23-10-2018 IPR013343 CRISPR-associated protein Cas4 A0127_05945 0de77f791ccb0b8a10891c7b2a51a72f 164 Gene3D G3DSA:2.40.50.100 97 163 2.2E-30 T 23-10-2018 A0127_05945 0de77f791ccb0b8a10891c7b2a51a72f 164 PIRSF PIRSF019115 1 164 2.2E-72 T 23-10-2018 IPR019217 Protein of unknown function DUF2118 A0127_05945 0de77f791ccb0b8a10891c7b2a51a72f 164 Pfam PF09891 Uncharacterized protein conserved in archaea (DUF2118) 2 163 4.1E-58 T 23-10-2018 IPR019217 Protein of unknown function DUF2118 A0127_02485 9607169cf15a787613e95bf468d799fc 221 Pfam PF00535 Glycosyl transferase family 2 8 167 1.0E-38 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A0127_02485 9607169cf15a787613e95bf468d799fc 221 Gene3D G3DSA:3.90.550.10 3 217 2.4E-58 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A0127_02485 9607169cf15a787613e95bf468d799fc 221 SUPERFAMILY SSF53448 5 209 7.7E-53 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A0127_05250 bb158116dce7e93d8ce46b4af8e87a62 427 Pfam PF00919 Uncharacterized protein family UPF0004 4 85 1.2E-20 T 23-10-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 A0127_05250 bb158116dce7e93d8ce46b4af8e87a62 427 TIGRFAM TIGR01578 MiaB-like-B: MiaB-like tRNA modifying enzyme, archaeal-type 4 422 1.8E-140 T 23-10-2018 IPR006466 MiaB-like tRNA modifying enzyme, archaeal-type Reactome: R-HSA-6782315 A0127_05250 bb158116dce7e93d8ce46b4af8e87a62 427 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 4 421 1.1E-130 T 23-10-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 A0127_05250 bb158116dce7e93d8ce46b4af8e87a62 427 SUPERFAMILY SSF102114 125 363 9.03E-55 T 23-10-2018 A0127_05250 bb158116dce7e93d8ce46b4af8e87a62 427 Pfam PF01938 TRAM domain 366 423 8.7E-5 T 23-10-2018 IPR002792 TRAM domain A0127_05250 bb158116dce7e93d8ce46b4af8e87a62 427 Pfam PF04055 Radical SAM superfamily 142 314 6.8E-25 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A0127_05250 bb158116dce7e93d8ce46b4af8e87a62 427 SMART SM00729 138 355 6.5E-62 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A0127_05250 bb158116dce7e93d8ce46b4af8e87a62 427 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 142 162 - T 23-10-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 A0127_05250 bb158116dce7e93d8ce46b4af8e87a62 427 Gene3D G3DSA:3.80.30.20 138 369 1.2E-76 T 23-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe A0127_05250 bb158116dce7e93d8ce46b4af8e87a62 427 Gene3D G3DSA:3.40.50.12160 2 127 5.6E-24 T 23-10-2018 IPR038135 Methylthiotransferase, N-terminal domain superfamily A0127_09610 36e3aaa3997c57209febd0c96bd2bff7 398 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 289 3.2E-55 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A0127_09610 36e3aaa3997c57209febd0c96bd2bff7 398 Gene3D G3DSA:3.50.50.60 106 324 1.3E-74 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A0127_09610 36e3aaa3997c57209febd0c96bd2bff7 398 SUPERFAMILY SSF51905 2 182 1.46E-38 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A0127_09610 36e3aaa3997c57209febd0c96bd2bff7 398 SUPERFAMILY SSF51905 137 301 2.19E-29 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A0127_09610 36e3aaa3997c57209febd0c96bd2bff7 398 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 98 106 1.3E-11 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A0127_09610 36e3aaa3997c57209febd0c96bd2bff7 398 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 2 24 1.3E-11 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A0127_09610 36e3aaa3997c57209febd0c96bd2bff7 398 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 133 157 1.3E-11 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A0127_09610 36e3aaa3997c57209febd0c96bd2bff7 398 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 254 272 1.3E-11 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A0127_09610 36e3aaa3997c57209febd0c96bd2bff7 398 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 220 241 1.3E-11 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A0127_09610 36e3aaa3997c57209febd0c96bd2bff7 398 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 244 266 6.3E-24 T 23-10-2018 A0127_09610 36e3aaa3997c57209febd0c96bd2bff7 398 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 3 22 6.3E-24 T 23-10-2018 A0127_09610 36e3aaa3997c57209febd0c96bd2bff7 398 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 137 155 6.3E-24 T 23-10-2018 A0127_09610 36e3aaa3997c57209febd0c96bd2bff7 398 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 218 234 6.3E-24 T 23-10-2018 A0127_09610 36e3aaa3997c57209febd0c96bd2bff7 398 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 97 115 6.3E-24 T 23-10-2018 A0127_09610 36e3aaa3997c57209febd0c96bd2bff7 398 Gene3D G3DSA:3.50.50.60 3 322 1.3E-74 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A0127_02465 ab86c3620ed191e2d4748a79defe60d8 182 Pfam PF06197 Protein of unknown function (DUF998) 13 174 7.7E-12 T 23-10-2018 IPR009339 Protein of unknown function DUF998 A0127_01790 17a0684342372deb509bcec24220ea5a 160 Gene3D G3DSA:1.10.10.10 1 56 9.9E-24 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A0127_01790 17a0684342372deb509bcec24220ea5a 160 SUPERFAMILY SSF46785 3 86 1.91E-14 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A0127_01790 17a0684342372deb509bcec24220ea5a 160 Gene3D G3DSA:3.30.70.920 57 160 6.8E-32 T 23-10-2018 A0127_01790 17a0684342372deb509bcec24220ea5a 160 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 4 20 8.5E-13 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A0127_01790 17a0684342372deb509bcec24220ea5a 160 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 31 50 8.5E-13 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A0127_01790 17a0684342372deb509bcec24220ea5a 160 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 20 31 8.5E-13 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A0127_01790 17a0684342372deb509bcec24220ea5a 160 SMART SM00344 4 116 1.1E-9 T 23-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A0127_01790 17a0684342372deb509bcec24220ea5a 160 Pfam PF13412 Winged helix-turn-helix DNA-binding 4 50 4.6E-16 T 23-10-2018 A0127_07325 0771a95231bc4ad4f84e7069d7c3d8ae 164 SUPERFAMILY SSF56024 26 160 2.22E-31 T 23-10-2018 A0127_07325 0771a95231bc4ad4f84e7069d7c3d8ae 164 Pfam PF13091 PLD-like domain 32 159 1.4E-23 T 23-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 A0127_07325 0771a95231bc4ad4f84e7069d7c3d8ae 164 Gene3D G3DSA:3.30.870.10 6 163 5.1E-37 T 23-10-2018 A0127_07325 0771a95231bc4ad4f84e7069d7c3d8ae 164 SMART SM00155 107 134 8.9E-5 T 23-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 A0127_08665 0bf1c75c8770745b273fa17991d6c7d2 151 Pfam PF00312 Ribosomal protein S15 73 148 4.3E-21 T 23-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A0127_08665 0bf1c75c8770745b273fa17991d6c7d2 151 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 90 133 2.0E-5 T 23-10-2018 A0127_08665 0bf1c75c8770745b273fa17991d6c7d2 151 Gene3D G3DSA:1.10.287.10 83 151 1.1E-32 T 23-10-2018 A0127_08665 0bf1c75c8770745b273fa17991d6c7d2 151 ProSitePatterns PS00362 Ribosomal protein S15 signature. 98 128 - T 23-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A0127_08665 0bf1c75c8770745b273fa17991d6c7d2 151 SMART SM01386 1 60 1.4E-35 T 23-10-2018 IPR012606 Ribosomal protein S13/S15, N-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_08665 0bf1c75c8770745b273fa17991d6c7d2 151 Gene3D G3DSA:1.10.8.1030 36 82 2.7E-21 T 23-10-2018 A0127_08665 0bf1c75c8770745b273fa17991d6c7d2 151 SMART SM01387 70 149 1.5E-28 T 23-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A0127_08665 0bf1c75c8770745b273fa17991d6c7d2 151 Hamap MF_01343_A 30S ribosomal protein S15 [rpsO]. 3 149 38.02 T 23-10-2018 IPR023029 Ribosomal protein S15P Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_08665 0bf1c75c8770745b273fa17991d6c7d2 151 Pfam PF08069 Ribosomal S13/S15 N-terminal domain 1 60 1.2E-27 T 23-10-2018 IPR012606 Ribosomal protein S13/S15, N-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_08665 0bf1c75c8770745b273fa17991d6c7d2 151 SUPERFAMILY SSF47060 66 142 8.83E-26 T 23-10-2018 IPR009068 S15/NS1, RNA-binding A0127_05895 47d92a4f549d795ad915545442b80771 365 SUPERFAMILY SSF143437 98 181 2.44E-10 T 23-10-2018 A0127_05895 47d92a4f549d795ad915545442b80771 365 SMART SM00981 86 182 4.4E-16 T 23-10-2018 IPR004114 THUMP domain GO:0003723 A0127_05895 47d92a4f549d795ad915545442b80771 365 Pfam PF02926 THUMP domain 31 182 1.9E-28 T 23-10-2018 IPR004114 THUMP domain GO:0003723 A0127_05895 47d92a4f549d795ad915545442b80771 365 Gene3D G3DSA:3.30.2130.30 1 189 1.0E-83 T 23-10-2018 A0127_05895 47d92a4f549d795ad915545442b80771 365 Pfam PF01170 Putative RNA methylase family UPF0020 191 358 6.6E-39 T 23-10-2018 IPR000241 Putative RNA methylase domain A0127_05895 47d92a4f549d795ad915545442b80771 365 SUPERFAMILY SSF53335 179 359 9.52E-39 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A0127_05895 47d92a4f549d795ad915545442b80771 365 ProSitePatterns PS01261 Uncharacterized protein family UPF0020 signature. 223 234 - T 23-10-2018 IPR000241 Putative RNA methylase domain A0127_05895 47d92a4f549d795ad915545442b80771 365 Gene3D G3DSA:3.40.50.150 190 365 5.7E-54 T 23-10-2018 A0127_00300 38d84ccaaa9620d6debc2277de1b0391 86 ProDom PD012670 RIBOSOMAL L35A 60S RIBONUCLEOPROTEIN L35A L35AE 50S RNA-BINDING TRNA-BINDING SEQUENCE 3 85 3.0E-40 T 23-10-2018 IPR001780 Ribosomal protein L35A GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_00300 38d84ccaaa9620d6debc2277de1b0391 86 Hamap MF_00573 50S ribosomal protein L35Ae [rpl35ae]. 2 86 23.085 T 23-10-2018 IPR001780 Ribosomal protein L35A GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_00300 38d84ccaaa9620d6debc2277de1b0391 86 SUPERFAMILY SSF50447 3 85 5.47E-23 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily A0127_00300 38d84ccaaa9620d6debc2277de1b0391 86 Pfam PF01247 Ribosomal protein L35Ae 3 85 1.0E-13 T 23-10-2018 IPR001780 Ribosomal protein L35A GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_00300 38d84ccaaa9620d6debc2277de1b0391 86 Gene3D G3DSA:2.40.10.190 1 86 7.2E-23 T 23-10-2018 IPR038661 Ribosomal protein L35A superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_00300 38d84ccaaa9620d6debc2277de1b0391 86 ProSitePatterns PS01105 Ribosomal protein L35Ae signature. 54 75 - T 23-10-2018 IPR018266 Ribosomal protein L35Ae, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_09525 a0f07fa589f8c8dc2e388f861fefd4df 298 Pfam PF01545 Cation efflux family 15 205 1.2E-50 T 23-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 A0127_09525 a0f07fa589f8c8dc2e388f861fefd4df 298 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 13 283 4.0E-93 T 23-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 A0127_09525 a0f07fa589f8c8dc2e388f861fefd4df 298 SUPERFAMILY SSF161111 11 206 3.4E-57 T 23-10-2018 IPR027469 Cation efflux transmembrane domain superfamily A0127_09525 a0f07fa589f8c8dc2e388f861fefd4df 298 Gene3D G3DSA:1.20.1510.10 11 205 1.9E-48 T 23-10-2018 IPR027469 Cation efflux transmembrane domain superfamily A0127_09525 a0f07fa589f8c8dc2e388f861fefd4df 298 Gene3D G3DSA:3.30.70.1350 206 284 1.9E-9 T 23-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 A0127_09525 a0f07fa589f8c8dc2e388f861fefd4df 298 SUPERFAMILY SSF160240 207 282 2.49E-16 T 23-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 A0127_09525 a0f07fa589f8c8dc2e388f861fefd4df 298 Pfam PF16916 Dimerisation domain of Zinc Transporter 210 282 7.4E-12 T 23-10-2018 IPR027470 Cation efflux protein, cytoplasmic domain A0127_05735 9e1a5fa46596ea99ead6df11affc98c1 415 Gene3D G3DSA:3.40.50.300 35 216 1.0E-109 T 23-10-2018 A0127_05735 9e1a5fa46596ea99ead6df11affc98c1 415 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 61 196 1.2E-9 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A0127_05735 9e1a5fa46596ea99ead6df11affc98c1 415 SMART SM00382 57 218 7.6E-11 T 23-10-2018 IPR003593 AAA+ ATPase domain A0127_05735 9e1a5fa46596ea99ead6df11affc98c1 415 Pfam PF09079 CDC6, C terminal winged helix domain 312 391 9.5E-26 T 23-10-2018 IPR015163 Cdc6, C-terminal Reactome: R-HSA-176187|Reactome: R-HSA-539107|Reactome: R-HSA-68689|Reactome: R-HSA-68827|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962 A0127_05735 9e1a5fa46596ea99ead6df11affc98c1 415 SUPERFAMILY SSF46785 297 402 2.72E-31 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A0127_05735 9e1a5fa46596ea99ead6df11affc98c1 415 SUPERFAMILY SSF52540 19 291 1.09E-55 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_05735 9e1a5fa46596ea99ead6df11affc98c1 415 Hamap MF_01407 ORC1-type DNA replication protein. 12 394 34.171 T 23-10-2018 IPR014277 Orc1/Cdc6-type DNA replication protein, archaea A0127_05735 9e1a5fa46596ea99ead6df11affc98c1 415 SMART SM01074 312 393 4.2E-35 T 23-10-2018 IPR015163 Cdc6, C-terminal Reactome: R-HSA-176187|Reactome: R-HSA-539107|Reactome: R-HSA-68689|Reactome: R-HSA-68827|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962 A0127_05735 9e1a5fa46596ea99ead6df11affc98c1 415 TIGRFAM TIGR02928 TIGR02928: orc1/cdc6 family replication initiation protein 19 383 2.1E-150 T 23-10-2018 IPR014277 Orc1/Cdc6-type DNA replication protein, archaea A0127_05735 9e1a5fa46596ea99ead6df11affc98c1 415 Gene3D G3DSA:1.10.10.10 304 404 3.8E-32 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A0127_05735 9e1a5fa46596ea99ead6df11affc98c1 415 Gene3D G3DSA:1.10.8.60 19 295 1.0E-109 T 23-10-2018 A0127_06180 e5e6e4e723b5217654435c69fc07a216 443 SUPERFAMILY SSF54368 19 84 1.57E-17 T 23-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A0127_06180 e5e6e4e723b5217654435c69fc07a216 443 Gene3D G3DSA:3.30.590.10 103 442 2.6E-127 T 23-10-2018 A0127_06180 e5e6e4e723b5217654435c69fc07a216 443 SUPERFAMILY SSF55931 101 441 3.34E-123 T 23-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 A0127_06180 e5e6e4e723b5217654435c69fc07a216 443 Pfam PF00120 Glutamine synthetase, catalytic domain 101 440 5.7E-130 T 23-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A0127_06180 e5e6e4e723b5217654435c69fc07a216 443 Gene3D G3DSA:3.10.20.70 9 102 8.5E-23 T 23-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A0127_06180 e5e6e4e723b5217654435c69fc07a216 443 ProSitePatterns PS00180 Glutamine synthetase signature 1. 52 70 - T 23-10-2018 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 A0127_06180 e5e6e4e723b5217654435c69fc07a216 443 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 138 441 9.2E-137 T 23-10-2018 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A0127_06180 e5e6e4e723b5217654435c69fc07a216 443 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 19 84 2.6E-20 T 23-10-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 A0127_06180 e5e6e4e723b5217654435c69fc07a216 443 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 226 241 - T 23-10-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 A0127_06180 e5e6e4e723b5217654435c69fc07a216 443 SMART SM01230 100 343 4.5E-136 T 23-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 A0127_07930 8ed3c4608536b7fac6f7535afdf3ada3 138 Gene3D G3DSA:3.30.70.1150 51 138 5.6E-37 T 23-10-2018 IPR027271 Acetolactate synthase/Transcription factor NikR, C-terminal A0127_07930 8ed3c4608536b7fac6f7535afdf3ada3 138 Gene3D G3DSA:1.10.1220.10 10 50 1.8E-21 T 23-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 A0127_07930 8ed3c4608536b7fac6f7535afdf3ada3 138 SUPERFAMILY SSF55021 53 133 2.22E-28 T 23-10-2018 A0127_07930 8ed3c4608536b7fac6f7535afdf3ada3 138 Pfam PF01402 Ribbon-helix-helix protein, copG family 5 42 1.8E-6 T 23-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 A0127_07930 8ed3c4608536b7fac6f7535afdf3ada3 138 Hamap MF_00476 Nickel-responsive regulator [nikR]. 3 133 30.332 T 23-10-2018 IPR022988 Nickel-responsive transcriptional regulator NikR GO:0003677|GO:0006355|GO:0010045|GO:0016151 A0127_07930 8ed3c4608536b7fac6f7535afdf3ada3 138 SUPERFAMILY SSF47598 3 48 5.71E-13 T 23-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 A0127_07930 8ed3c4608536b7fac6f7535afdf3ada3 138 Pfam PF08753 NikR C terminal nickel binding domain 55 131 4.9E-33 T 23-10-2018 IPR014864 Transcription factor, NikR, nickel binding C-terminal A0127_10040 eb3faec15b3c228796e20e0c0748bb53 267 Pfam PF13230 Glutamine amidotransferases class-II 31 192 7.0E-9 T 23-10-2018 IPR026869 Putative glutamine amidotransferase type 2 A0127_10040 eb3faec15b3c228796e20e0c0748bb53 267 Gene3D G3DSA:3.60.20.10 18 258 2.2E-19 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A0127_10040 eb3faec15b3c228796e20e0c0748bb53 267 SUPERFAMILY SSF56235 2 259 1.98E-19 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A0127_03000 99948a30ca0012af3ba3493c7c3f63da 223 SMART SM01211 1 221 6.0E-133 T 23-10-2018 A0127_03000 99948a30ca0012af3ba3493c7c3f63da 223 Hamap MF_00421 Phosphoribosylformylglycinamidine synthase subunit PurQ [purQ]. 2 219 45.123 T 23-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A0127_03000 99948a30ca0012af3ba3493c7c3f63da 223 SUPERFAMILY SSF52317 2 221 6.39E-79 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A0127_03000 99948a30ca0012af3ba3493c7c3f63da 223 PIRSF PIRSF001586 1 223 5.9E-85 T 23-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A0127_03000 99948a30ca0012af3ba3493c7c3f63da 223 TIGRFAM TIGR01737 FGAM_synth_I: phosphoribosylformylglycinamidine synthase I 2 220 1.4E-97 T 23-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 A0127_03000 99948a30ca0012af3ba3493c7c3f63da 223 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 2 220 3.4E-51 T 23-10-2018 A0127_03000 99948a30ca0012af3ba3493c7c3f63da 223 Gene3D G3DSA:3.40.50.880 1 223 4.1E-80 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A0127_03205 0de0b27f8e249b4feb84a30ad2b3ac02 166 Gene3D G3DSA:3.40.50.880 1 166 1.4E-52 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A0127_03205 0de0b27f8e249b4feb84a30ad2b3ac02 166 TIGRFAM TIGR01382 PfpI: intracellular protease, PfpI family 2 166 2.9E-67 T 23-10-2018 IPR006286 Deglycase PfpI A0127_03205 0de0b27f8e249b4feb84a30ad2b3ac02 166 SUPERFAMILY SSF52317 1 165 1.72E-52 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A0127_03205 0de0b27f8e249b4feb84a30ad2b3ac02 166 Pfam PF01965 DJ-1/PfpI family 1 163 9.3E-59 T 23-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 A0127_07220 976745dab8dd193257c1d14d524586c8 585 Gene3D G3DSA:2.40.30.20 1 69 2.9E-30 T 23-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A0127_07220 976745dab8dd193257c1d14d524586c8 585 Gene3D G3DSA:2.40.50.100 113 184 5.4E-186 T 23-10-2018 A0127_07220 976745dab8dd193257c1d14d524586c8 585 Pfam PF16886 ATPsynthase alpha/beta subunit N-term extension 82 202 1.7E-48 T 23-10-2018 IPR031686 ATPsynthase alpha/beta subunit, N-terminal extension KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A0127_07220 976745dab8dd193257c1d14d524586c8 585 SUPERFAMILY SSF52540 163 440 1.69E-85 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_07220 976745dab8dd193257c1d14d524586c8 585 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 4 66 8.6E-15 T 23-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A0127_07220 976745dab8dd193257c1d14d524586c8 585 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 425 434 - T 23-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A0127_07220 976745dab8dd193257c1d14d524586c8 585 Gene3D G3DSA:3.40.50.300 70 434 5.4E-186 T 23-10-2018 A0127_07220 976745dab8dd193257c1d14d524586c8 585 TIGRFAM TIGR01043 ATP_syn_A_arch: ATP synthase archaeal, A subunit 1 580 0.0 T 23-10-2018 IPR005726 ATP synthase alpha chain, archaea GO:0015986|GO:0033178|GO:0046961 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A0127_07220 976745dab8dd193257c1d14d524586c8 585 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 211 434 7.7E-93 T 23-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A0127_07220 976745dab8dd193257c1d14d524586c8 585 Hamap MF_00309 V-type ATP synthase alpha chain [atpA]. 1 583 54.91 T 23-10-2018 IPR022878 V-type ATP synthase catalytic alpha chain GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A0127_07220 976745dab8dd193257c1d14d524586c8 585 SUPERFAMILY SSF50615 1 68 5.23E-14 T 23-10-2018 IPR036121 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A0127_07220 976745dab8dd193257c1d14d524586c8 585 SMART SM00382 223 411 0.0017 T 23-10-2018 IPR003593 AAA+ ATPase domain A0127_07220 976745dab8dd193257c1d14d524586c8 585 Gene3D G3DSA:1.10.1140.10 435 585 2.5E-60 T 23-10-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A0127_07220 976745dab8dd193257c1d14d524586c8 585 SUPERFAMILY SSF47917 447 552 8.11E-27 T 23-10-2018 A0127_01730 12e4d33eaaab0e2c15ffd9a71a4aae80 403 Pfam PF02441 Flavoprotein 19 188 9.4E-42 T 23-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 A0127_01730 12e4d33eaaab0e2c15ffd9a71a4aae80 403 Gene3D G3DSA:3.40.50.1950 15 186 2.9E-48 T 23-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 A0127_01730 12e4d33eaaab0e2c15ffd9a71a4aae80 403 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 18 399 3.2E-128 T 23-10-2018 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5|MetaCyc: PWY-7851 A0127_01730 12e4d33eaaab0e2c15ffd9a71a4aae80 403 SUPERFAMILY SSF52507 18 217 2.09E-47 T 23-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 A0127_01730 12e4d33eaaab0e2c15ffd9a71a4aae80 403 SUPERFAMILY SSF102645 180 402 6.67E-66 T 23-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 A0127_01730 12e4d33eaaab0e2c15ffd9a71a4aae80 403 Gene3D G3DSA:3.40.50.10300 187 403 5.1E-70 T 23-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 A0127_01730 12e4d33eaaab0e2c15ffd9a71a4aae80 403 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 193 375 4.7E-56 T 23-10-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 A0127_07810 ce9b0201832c1dedc65b1bd8b9f4c144 276 SUPERFAMILY SSF53167 16 246 1.57E-75 T 23-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 A0127_07810 ce9b0201832c1dedc65b1bd8b9f4c144 276 TIGRFAM TIGR01718 Uridine-psphlse: uridine phosphorylase 17 256 9.5E-97 T 23-10-2018 IPR010058 Uridine phosphorylase GO:0004850|GO:0005737|GO:0009166 KEGG: 00240+2.4.2.3|KEGG: 00983+2.4.2.3|MetaCyc: PWY-5532 A0127_07810 ce9b0201832c1dedc65b1bd8b9f4c144 276 Pfam PF01048 Phosphorylase superfamily 30 255 6.3E-45 T 23-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 A0127_07810 ce9b0201832c1dedc65b1bd8b9f4c144 276 Gene3D G3DSA:3.40.50.1580 6 260 2.5E-86 T 23-10-2018 A0127_07810 ce9b0201832c1dedc65b1bd8b9f4c144 276 ProSitePatterns PS01232 Purine and other phosphorylases family 1 signature. 75 90 - T 23-10-2018 IPR018016 Nucleoside phosphorylase, conserved site GO:0016763 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-73614|Reactome: R-HSA-73621 A0127_04670 94cad845dd0621be4a8d03b15bb5d9bf 154 Gene3D G3DSA:1.10.10.10 6 81 5.4E-8 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A0127_04670 94cad845dd0621be4a8d03b15bb5d9bf 154 Pfam PF01037 Lrp/AsnC ligand binding domain 87 153 1.2E-8 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A0127_04670 94cad845dd0621be4a8d03b15bb5d9bf 154 Gene3D G3DSA:3.30.70.920 82 154 1.9E-10 T 23-10-2018 A0127_04670 94cad845dd0621be4a8d03b15bb5d9bf 154 SMART SM00418 5 105 0.0086 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A0127_04670 94cad845dd0621be4a8d03b15bb5d9bf 154 SUPERFAMILY SSF54909 85 153 1.88E-8 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel A0127_04670 94cad845dd0621be4a8d03b15bb5d9bf 154 SMART SM00419 21 72 1.8E-7 T 23-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 A0127_04670 94cad845dd0621be4a8d03b15bb5d9bf 154 SUPERFAMILY SSF46785 7 82 1.16E-11 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A0127_04670 94cad845dd0621be4a8d03b15bb5d9bf 154 Pfam PF12802 MarR family 7 65 4.6E-8 T 23-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A0127_05275 307c71d8e80d4a4c69ba3aceb9270b01 428 ProSitePatterns PS00508 Nickel-dependent hydrogenases large subunit signature 2. 415 424 - T 23-10-2018 IPR018194 Nickel-dependent hydrogenase, large subunit, nickel binding site GO:0008901|GO:0016151|GO:0055114 A0127_05275 307c71d8e80d4a4c69ba3aceb9270b01 428 Gene3D G3DSA:1.10.645.10 6 424 4.2E-106 T 23-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A0127_05275 307c71d8e80d4a4c69ba3aceb9270b01 428 Pfam PF00374 Nickel-dependent hydrogenase 243 424 5.7E-11 T 23-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 A0127_05275 307c71d8e80d4a4c69ba3aceb9270b01 428 Pfam PF00374 Nickel-dependent hydrogenase 43 122 1.2E-10 T 23-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 A0127_05275 307c71d8e80d4a4c69ba3aceb9270b01 428 SUPERFAMILY SSF56762 8 424 1.18E-96 T 23-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A0127_07470 c41ebc88b21cd5739092c0495af6cf21 346 Pfam PF00297 Ribosomal protein L3 3 346 3.7E-91 T 23-10-2018 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A0127_07470 c41ebc88b21cd5739092c0495af6cf21 346 Gene3D G3DSA:3.30.1430.10 77 188 7.8E-123 T 23-10-2018 A0127_07470 c41ebc88b21cd5739092c0495af6cf21 346 ProSitePatterns PS00474 Ribosomal protein L3 signature. 193 216 - T 23-10-2018 IPR019926 Ribosomal protein L3, conserved site A0127_07470 c41ebc88b21cd5739092c0495af6cf21 346 TIGRFAM TIGR03626 L3_arch: ribosomal protein uL3 5 345 3.1E-136 T 23-10-2018 IPR019928 Ribosomal protein L3, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 A0127_07470 c41ebc88b21cd5739092c0495af6cf21 346 Gene3D G3DSA:4.10.960.10 6 257 7.8E-123 T 23-10-2018 A0127_07470 c41ebc88b21cd5739092c0495af6cf21 346 Gene3D G3DSA:2.40.30.10 39 326 7.8E-123 T 23-10-2018 A0127_07470 c41ebc88b21cd5739092c0495af6cf21 346 Hamap MF_01325_A 50S ribosomal protein L3 [rplC]. 1 346 50.139 T 23-10-2018 IPR019928 Ribosomal protein L3, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 A0127_07470 c41ebc88b21cd5739092c0495af6cf21 346 SUPERFAMILY SSF50447 3 346 1.15E-96 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily A0127_08850 6cfbc8c517a3f922a7f6f624397bcefe 394 SUPERFAMILY SSF56762 41 394 3.01E-95 T 23-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A0127_08850 6cfbc8c517a3f922a7f6f624397bcefe 394 Gene3D G3DSA:1.10.645.20 30 394 2.0E-114 T 23-10-2018 IPR038290 NADH-quinone oxidoreductase, subunit D superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A0127_08850 6cfbc8c517a3f922a7f6f624397bcefe 394 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 142 394 8.7E-73 T 23-10-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A0127_08850 6cfbc8c517a3f922a7f6f624397bcefe 394 ProSitePatterns PS00535 Respiratory chain NADH dehydrogenase 49 Kd subunit signature. 64 75 - T 23-10-2018 IPR014029 NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A0127_03965 20eb16ed4a10133ba0a618dee97ae95e 225 PIRSF PIRSF039123 1 225 5.0E-79 T 23-10-2018 IPR030662 Diphthine--ammonia ligase/Uncharacterised protein MJ0570 MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 A0127_03965 20eb16ed4a10133ba0a618dee97ae95e 225 TIGRFAM TIGR00290 MJ0570_dom: MJ0570-related uncharacterized domain 1 220 1.0E-84 T 23-10-2018 IPR002761 Diphthamide synthase domain MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 A0127_03965 20eb16ed4a10133ba0a618dee97ae95e 225 Gene3D G3DSA:3.90.1490.10 137 225 6.0E-32 T 23-10-2018 A0127_03965 20eb16ed4a10133ba0a618dee97ae95e 225 TIGRFAM TIGR03679 arCOG00187: arCOG00187 universal archaeal metal-binding-domain/4Fe-4S-binding-domain containing ABC transporter, ATP-binding protein 4 215 1.2E-87 T 23-10-2018 IPR022427 Uncharacterised protein MJ0570, ATP-binding A0127_03965 20eb16ed4a10133ba0a618dee97ae95e 225 SUPERFAMILY SSF52402 1 220 2.79E-73 T 23-10-2018 A0127_03965 20eb16ed4a10133ba0a618dee97ae95e 225 TIGRFAM TIGR00289 TIGR00289: TIGR00289 family protein 1 222 7.0E-92 T 23-10-2018 IPR005237 Uncharacterised protein MJ0570 A0127_03965 20eb16ed4a10133ba0a618dee97ae95e 225 Pfam PF01902 Diphthamide synthase 1 220 8.9E-87 T 23-10-2018 IPR002761 Diphthamide synthase domain MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 A0127_03965 20eb16ed4a10133ba0a618dee97ae95e 225 Gene3D G3DSA:3.40.50.620 1 134 1.5E-46 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A0127_03750 b297a36b1300b10d787a52549cb94420 292 SMART SM00849 15 200 1.7E-9 T 23-10-2018 IPR001279 Metallo-beta-lactamase A0127_03750 b297a36b1300b10d787a52549cb94420 292 Gene3D G3DSA:3.60.15.10 2 220 3.1E-27 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A0127_03750 b297a36b1300b10d787a52549cb94420 292 SUPERFAMILY SSF56281 14 277 2.52E-35 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A0127_03750 b297a36b1300b10d787a52549cb94420 292 Pfam PF00753 Metallo-beta-lactamase superfamily 15 193 5.1E-10 T 23-10-2018 IPR001279 Metallo-beta-lactamase A0127_04320 60338657095b00cf1ad46a63e9e3e2cd 242 SUPERFAMILY SSF52540 6 213 9.25E-56 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_04320 60338657095b00cf1ad46a63e9e3e2cd 242 Gene3D G3DSA:3.40.50.300 4 236 1.6E-60 T 23-10-2018 A0127_04320 60338657095b00cf1ad46a63e9e3e2cd 242 SMART SM00382 26 201 5.5E-16 T 23-10-2018 IPR003593 AAA+ ATPase domain A0127_04320 60338657095b00cf1ad46a63e9e3e2cd 242 Pfam PF00005 ABC transporter 17 154 2.3E-26 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A0127_04320 60338657095b00cf1ad46a63e9e3e2cd 242 ProSitePatterns PS00211 ABC transporters family signature. 126 140 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A0127_05845 93d2b98b06a5560d9312f07a12a8b928 97 Gene3D G3DSA:3.30.460.10 2 96 1.1E-25 T 23-10-2018 A0127_05845 93d2b98b06a5560d9312f07a12a8b928 97 SUPERFAMILY SSF81301 3 97 4.3E-26 T 23-10-2018 A0127_05845 93d2b98b06a5560d9312f07a12a8b928 97 Pfam PF01909 Nucleotidyltransferase domain 12 91 1.5E-15 T 23-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 A0127_02050 977351242b69f2135eb697f7fc74bc3a 188 Gene3D G3DSA:1.20.58.1030 1 113 1.4E-51 T 23-10-2018 A0127_02050 977351242b69f2135eb697f7fc74bc3a 188 Gene3D G3DSA:3.40.5.50 129 188 9.7E-34 T 23-10-2018 A0127_02050 977351242b69f2135eb697f7fc74bc3a 188 PIRSF PIRSF019075 1 188 3.1E-84 T 23-10-2018 IPR016745 Uncharacterised conserved protein UCP019075 A0127_07340 0ab6a4403afb6f49a672f4242fb33d4b 203 Pfam PF01914 MarC family integral membrane protein 6 196 1.7E-30 T 23-10-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 A0127_06680 ef694090ac4a5dcce192094727a0a5b3 379 Pfam PF14306 PUA-like domain 4 156 3.5E-51 T 23-10-2018 IPR025980 ATP-sulfurylase PUA-like domain KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 A0127_06680 ef694090ac4a5dcce192094727a0a5b3 379 Hamap MF_00066 Sulfate adenylyltransferase [sat]. 26 376 50.772 T 23-10-2018 IPR020792 Sulphate adenylyltransferase, prokaryotic-type GO:0000103|GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 A0127_06680 ef694090ac4a5dcce192094727a0a5b3 379 Gene3D G3DSA:3.10.400.10 1 159 6.8E-49 T 23-10-2018 A0127_06680 ef694090ac4a5dcce192094727a0a5b3 379 TIGRFAM TIGR00339 sopT: sulfate adenylyltransferase 5 371 2.5E-121 T 23-10-2018 IPR002650 Sulphate adenylyltransferase GO:0000103|GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 A0127_06680 ef694090ac4a5dcce192094727a0a5b3 379 SUPERFAMILY SSF88697 4 161 1.09E-49 T 23-10-2018 IPR015947 PUA-like superfamily A0127_06680 ef694090ac4a5dcce192094727a0a5b3 379 Gene3D G3DSA:3.40.50.620 164 373 5.3E-90 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A0127_06680 ef694090ac4a5dcce192094727a0a5b3 379 Pfam PF01747 ATP-sulfurylase 164 372 1.8E-86 T 23-10-2018 IPR024951 Sulphate adenylyltransferase catalytic domain GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 A0127_06680 ef694090ac4a5dcce192094727a0a5b3 379 SUPERFAMILY SSF52374 164 372 6.22E-78 T 23-10-2018 A0127_09975 e879aee18cba7c55de1341065316924b 232 SUPERFAMILY SSF52540 5 228 4.5E-41 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_09975 e879aee18cba7c55de1341065316924b 232 Pfam PF06745 KaiC 6 229 5.6E-51 T 23-10-2018 IPR014774 KaiC-like domain A0127_09975 e879aee18cba7c55de1341065316924b 232 PRINTS PR01874 DNA repair protein radA signature 15 43 3.0E-9 T 23-10-2018 A0127_09975 e879aee18cba7c55de1341065316924b 232 PRINTS PR01874 DNA repair protein radA signature 57 74 3.0E-9 T 23-10-2018 A0127_09975 e879aee18cba7c55de1341065316924b 232 Gene3D G3DSA:3.40.50.300 4 231 2.0E-57 T 23-10-2018 A0127_04085 bfbec89d499559ffd59f29ff9a1788d8 178 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 87 122 - T 23-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 A0127_04085 bfbec89d499559ffd59f29ff9a1788d8 178 SUPERFAMILY SSF53927 23 144 3.35E-40 T 23-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 A0127_04085 bfbec89d499559ffd59f29ff9a1788d8 178 Gene3D G3DSA:3.40.140.10 19 168 1.3E-48 T 23-10-2018 A0127_04085 bfbec89d499559ffd59f29ff9a1788d8 178 PIRSF PIRSF006019 13 169 1.3E-56 T 23-10-2018 IPR016473 Deoxycytidylate deaminase GO:0004132|GO:0006220|GO:0008270 KEGG: 00240+3.5.4.12|MetaCyc: PWY-7210|Reactome: R-HSA-499943 A0127_04085 bfbec89d499559ffd59f29ff9a1788d8 178 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 22 133 5.2E-29 T 23-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain A0127_03340 c750cdeeb3cec8fc151d39bd0091c2e1 190 Hamap MF_00408 TATA-box-binding protein [tbp]. 5 184 37.587 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 A0127_03340 c750cdeeb3cec8fc151d39bd0091c2e1 190 ProSitePatterns PS00351 Transcription factor TFIID repeat signature. 129 178 - T 23-10-2018 IPR030491 TATA-box binding protein, conserved site A0127_03340 c750cdeeb3cec8fc151d39bd0091c2e1 190 Gene3D G3DSA:3.30.310.10 98 182 5.9E-35 T 23-10-2018 IPR012295 TBP domain superfamily A0127_03340 c750cdeeb3cec8fc151d39bd0091c2e1 190 Gene3D G3DSA:3.30.310.10 16 97 1.2E-31 T 23-10-2018 IPR012295 TBP domain superfamily A0127_03340 c750cdeeb3cec8fc151d39bd0091c2e1 190 Pfam PF00352 Transcription factor TFIID (or TATA-binding protein, TBP) 9 89 1.5E-26 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 A0127_03340 c750cdeeb3cec8fc151d39bd0091c2e1 190 Pfam PF00352 Transcription factor TFIID (or TATA-binding protein, TBP) 100 181 2.6E-28 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 A0127_03340 c750cdeeb3cec8fc151d39bd0091c2e1 190 PRINTS PR00686 Transcription initiation factor TFIID signature 125 140 3.9E-42 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 A0127_03340 c750cdeeb3cec8fc151d39bd0091c2e1 190 PRINTS PR00686 Transcription initiation factor TFIID signature 35 54 3.9E-42 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 A0127_03340 c750cdeeb3cec8fc151d39bd0091c2e1 190 PRINTS PR00686 Transcription initiation factor TFIID signature 102 118 3.9E-42 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 A0127_03340 c750cdeeb3cec8fc151d39bd0091c2e1 190 PRINTS PR00686 Transcription initiation factor TFIID signature 144 160 3.9E-42 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 A0127_03340 c750cdeeb3cec8fc151d39bd0091c2e1 190 PRINTS PR00686 Transcription initiation factor TFIID signature 11 26 3.9E-42 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 A0127_03340 c750cdeeb3cec8fc151d39bd0091c2e1 190 PRINTS PR00686 Transcription initiation factor TFIID signature 54 72 3.9E-42 T 23-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 A0127_03340 c750cdeeb3cec8fc151d39bd0091c2e1 190 SUPERFAMILY SSF55945 5 95 5.5E-29 T 23-10-2018 A0127_03340 c750cdeeb3cec8fc151d39bd0091c2e1 190 SUPERFAMILY SSF55945 95 182 1.88E-30 T 23-10-2018 A0127_07685 20a63daeb6a0f607b3176df6e1200025 135 Pfam PF00380 Ribosomal protein S9/S16 8 135 9.2E-31 T 23-10-2018 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 A0127_07685 20a63daeb6a0f607b3176df6e1200025 135 Gene3D G3DSA:3.30.230.10 1 135 6.0E-51 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A0127_07685 20a63daeb6a0f607b3176df6e1200025 135 TIGRFAM TIGR03627 uS9_arch: ribosomal protein uS9 3 135 4.6E-62 T 23-10-2018 IPR019958 Ribosomal protein S9, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 A0127_07685 20a63daeb6a0f607b3176df6e1200025 135 Hamap MF_00532_A 30S ribosomal protein S9 [rpsI]. 3 135 37.245 T 23-10-2018 IPR019958 Ribosomal protein S9, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 A0127_07685 20a63daeb6a0f607b3176df6e1200025 135 ProSitePatterns PS00360 Ribosomal protein S9 signature. 68 86 - T 23-10-2018 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 A0127_07685 20a63daeb6a0f607b3176df6e1200025 135 SUPERFAMILY SSF54211 3 135 5.69E-34 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A0127_05445 b369642f20485cf6feb493ebc43cf099 150 SUPERFAMILY SSF46785 5 63 7.44E-12 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A0127_05445 b369642f20485cf6feb493ebc43cf099 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 32 51 9.2E-14 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A0127_05445 b369642f20485cf6feb493ebc43cf099 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 5 21 9.2E-14 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A0127_05445 b369642f20485cf6feb493ebc43cf099 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 21 32 9.2E-14 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A0127_05445 b369642f20485cf6feb493ebc43cf099 150 Gene3D G3DSA:3.30.70.920 59 150 4.1E-23 T 23-10-2018 A0127_05445 b369642f20485cf6feb493ebc43cf099 150 SMART SM00344 5 114 1.8E-44 T 23-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A0127_05445 b369642f20485cf6feb493ebc43cf099 150 Gene3D G3DSA:1.10.10.10 2 56 2.9E-19 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A0127_05445 b369642f20485cf6feb493ebc43cf099 150 SUPERFAMILY SSF54909 65 147 2.01E-17 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel A0127_05445 b369642f20485cf6feb493ebc43cf099 150 Pfam PF01037 Lrp/AsnC ligand binding domain 79 142 9.1E-15 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A0127_05445 b369642f20485cf6feb493ebc43cf099 150 Pfam PF13412 Winged helix-turn-helix DNA-binding 5 52 3.2E-15 T 23-10-2018 A0127_05210 b4f17383bee04001ab699d2d465a3d07 305 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A0127_05210 b4f17383bee04001ab699d2d465a3d07 305 Gene3D G3DSA:3.40.50.300 1 241 2.0E-60 T 23-10-2018 A0127_05210 b4f17383bee04001ab699d2d465a3d07 305 Pfam PF13732 Domain of unknown function (DUF4162) 221 304 3.1E-7 T 23-10-2018 IPR025302 Domain of unknown function DUF4162 A0127_05210 b4f17383bee04001ab699d2d465a3d07 305 SUPERFAMILY SSF52540 2 229 3.15E-57 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_05210 b4f17383bee04001ab699d2d465a3d07 305 Pfam PF00005 ABC transporter 17 167 1.7E-30 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A0127_05210 b4f17383bee04001ab699d2d465a3d07 305 SMART SM00382 26 219 2.0E-13 T 23-10-2018 IPR003593 AAA+ ATPase domain A0127_01215 513770acd9a43cf17b0547f7157fe201 338 Gene3D G3DSA:3.40.630.10 11 333 3.6E-113 T 23-10-2018 A0127_01215 513770acd9a43cf17b0547f7157fe201 338 SUPERFAMILY SSF101821 67 178 6.26E-27 T 23-10-2018 A0127_01215 513770acd9a43cf17b0547f7157fe201 338 SUPERFAMILY SSF53187 2 335 7.54E-48 T 23-10-2018 A0127_01215 513770acd9a43cf17b0547f7157fe201 338 PIRSF PIRSF001123 1 336 2.9E-37 T 23-10-2018 IPR008007 Peptidase M42 A0127_01215 513770acd9a43cf17b0547f7157fe201 338 Pfam PF05343 M42 glutamyl aminopeptidase 48 328 1.3E-70 T 23-10-2018 IPR008007 Peptidase M42 A0127_01215 513770acd9a43cf17b0547f7157fe201 338 Gene3D G3DSA:2.40.30.40 70 164 3.6E-113 T 23-10-2018 IPR023367 Peptidase M42, domain 2 A0127_04605 c1f59f199978cd38d610347eb2a6b19a 310 SUPERFAMILY SSF48371 25 246 2.21E-7 T 23-10-2018 IPR016024 Armadillo-type fold A0127_04605 c1f59f199978cd38d610347eb2a6b19a 310 Gene3D G3DSA:1.25.10.10 1 246 1.2E-28 T 23-10-2018 IPR011989 Armadillo-like helical A0127_01270 0cdb8334d9bc1385e8b02228d150fb2d 580 TIGRFAM TIGR00432 arcsn_tRNA_tgt: tRNA-guanine(15) transglycosylase 6 389 1.5E-168 T 23-10-2018 IPR004804 tRNA-guanine(15) transglycosylase GO:0006400|GO:0016763 MetaCyc: PWY-6711|MetaCyc: PWY-7923 A0127_01270 0cdb8334d9bc1385e8b02228d150fb2d 580 Pfam PF01472 PUA domain 506 577 5.7E-17 T 23-10-2018 IPR002478 PUA domain GO:0003723 A0127_01270 0cdb8334d9bc1385e8b02228d150fb2d 580 Pfam PF14810 Patch-forming domain C2 of tRNA-guanine transglycosylase 436 503 8.2E-24 T 23-10-2018 IPR029402 tRNA-guanine transglycosylase, patch-forming domain C2 MetaCyc: PWY-6711|MetaCyc: PWY-7923 A0127_01270 0cdb8334d9bc1385e8b02228d150fb2d 580 SMART SM00359 505 579 3.5E-21 T 23-10-2018 IPR002478 PUA domain GO:0003723 A0127_01270 0cdb8334d9bc1385e8b02228d150fb2d 580 TIGRFAM TIGR00449 tgt_general: tRNA-guanine family transglycosylase 6 337 3.1E-88 T 23-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 A0127_01270 0cdb8334d9bc1385e8b02228d150fb2d 580 Pfam PF01702 Queuine tRNA-ribosyltransferase 109 330 1.7E-42 T 23-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 A0127_01270 0cdb8334d9bc1385e8b02228d150fb2d 580 SUPERFAMILY SSF51713 4 354 2.35E-117 T 23-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 A0127_01270 0cdb8334d9bc1385e8b02228d150fb2d 580 Hamap MF_01634 tRNA-guanine(15) transglycosylase [tgtA]. 6 531 48.611 T 23-10-2018 IPR004804 tRNA-guanine(15) transglycosylase GO:0006400|GO:0016763 MetaCyc: PWY-6711|MetaCyc: PWY-7923 A0127_01270 0cdb8334d9bc1385e8b02228d150fb2d 580 Gene3D G3DSA:3.90.1020.10 357 426 4.3E-27 T 23-10-2018 IPR038370 TGT, C1 domain superfamily MetaCyc: PWY-6711|MetaCyc: PWY-7923 A0127_01270 0cdb8334d9bc1385e8b02228d150fb2d 580 Gene3D G3DSA:3.20.20.105 2 356 2.5E-125 T 23-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 A0127_01270 0cdb8334d9bc1385e8b02228d150fb2d 580 Gene3D G3DSA:2.30.130.10 502 579 1.5E-32 T 23-10-2018 IPR036974 PUA domain superfamily GO:0003723 A0127_01270 0cdb8334d9bc1385e8b02228d150fb2d 580 Gene3D G3DSA:3.10.450.90 427 501 4.5E-28 T 23-10-2018 IPR038250 TGT, patch-forming C2 domain superfamily MetaCyc: PWY-6711|MetaCyc: PWY-7923 A0127_01270 0cdb8334d9bc1385e8b02228d150fb2d 580 SUPERFAMILY SSF88697 504 578 1.1E-20 T 23-10-2018 IPR015947 PUA-like superfamily A0127_01270 0cdb8334d9bc1385e8b02228d150fb2d 580 TIGRFAM TIGR00451 unchar_dom_2: uncharacterized domain 2 485 575 1.5E-10 T 23-10-2018 IPR004521 Uncharacterised domain CHP00451 GO:0003723 A0127_01270 0cdb8334d9bc1385e8b02228d150fb2d 580 SUPERFAMILY SSF88802 357 502 1.05E-42 T 23-10-2018 A0127_01270 0cdb8334d9bc1385e8b02228d150fb2d 580 Pfam PF14809 C1 domain of tRNA-guanine transglycosylase dimerisation 357 426 7.3E-44 T 23-10-2018 IPR032729 tRNA-guanine(15) transglycosylase, C1 domain MetaCyc: PWY-6711|MetaCyc: PWY-7923 A0127_00325 2f22a4fc82ec79fdae3654b32bc03a58 357 Gene3D G3DSA:2.30.30.870 1 130 3.1E-38 T 23-10-2018 IPR038069 Pelota/DOM34, N-terminal domain A0127_00325 2f22a4fc82ec79fdae3654b32bc03a58 357 SUPERFAMILY SSF53137 131 259 1.13E-31 T 23-10-2018 A0127_00325 2f22a4fc82ec79fdae3654b32bc03a58 357 Gene3D G3DSA:3.30.420.60 133 257 1.0E-36 T 23-10-2018 A0127_00325 2f22a4fc82ec79fdae3654b32bc03a58 357 Pfam PF03465 eRF1 domain 3 261 356 3.3E-25 T 23-10-2018 IPR005142 eRF1 domain 3 A0127_00325 2f22a4fc82ec79fdae3654b32bc03a58 357 Gene3D G3DSA:3.30.1330.30 258 357 1.6E-32 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like A0127_00325 2f22a4fc82ec79fdae3654b32bc03a58 357 TIGRFAM TIGR00111 pelota: mRNA surveillance protein pelota 1 356 8.4E-114 T 23-10-2018 IPR004405 Translation release factor pelota GO:0070481|GO:0070966|GO:0071025 A0127_00325 2f22a4fc82ec79fdae3654b32bc03a58 357 Pfam PF03464 eRF1 domain 2 136 250 1.1E-17 T 23-10-2018 IPR005141 eRF1 domain 2 A0127_00325 2f22a4fc82ec79fdae3654b32bc03a58 357 SUPERFAMILY SSF159065 1 128 1.18E-36 T 23-10-2018 IPR038069 Pelota/DOM34, N-terminal domain A0127_00325 2f22a4fc82ec79fdae3654b32bc03a58 357 Pfam PF03463 eRF1 domain 1 5 127 1.0E-28 T 23-10-2018 IPR005140 eRF1 domain 1/Pelota-like A0127_00325 2f22a4fc82ec79fdae3654b32bc03a58 357 Hamap MF_01853 Protein pelota homolog [pelA]. 2 356 37.401 T 23-10-2018 IPR023521 Translation release factor pelota, archaea GO:0070481|GO:0070966|GO:0071025 A0127_00325 2f22a4fc82ec79fdae3654b32bc03a58 357 SMART SM01194 1 129 2.1E-48 T 23-10-2018 IPR005140 eRF1 domain 1/Pelota-like A0127_00325 2f22a4fc82ec79fdae3654b32bc03a58 357 SUPERFAMILY SSF55315 251 356 1.88E-29 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like A0127_02715 bc429a1cb3f0ee7c7152a4f950a93ee8 428 Gene3D G3DSA:3.40.50.300 1 212 2.1E-88 T 23-10-2018 A0127_02715 bc429a1cb3f0ee7c7152a4f950a93ee8 428 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 59 74 - T 23-10-2018 IPR031157 Tr-type G domain, conserved site A0127_02715 bc429a1cb3f0ee7c7152a4f950a93ee8 428 Pfam PF00009 Elongation factor Tu GTP binding domain 5 209 1.6E-59 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A0127_02715 bc429a1cb3f0ee7c7152a4f950a93ee8 428 Hamap MF_00118_A Elongation factor Tu [tuf]. 2 427 61.527 T 23-10-2018 IPR004539 Translation elongation factor EF1A, eukaryotic/archaeal GO:0003746|GO:0005525|GO:0005737|GO:0006414 Reactome: R-HSA-156842 A0127_02715 bc429a1cb3f0ee7c7152a4f950a93ee8 428 Pfam PF03143 Elongation factor Tu C-terminal domain 317 424 1.1E-37 T 23-10-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal A0127_02715 bc429a1cb3f0ee7c7152a4f950a93ee8 428 SUPERFAMILY SSF52540 3 236 7.36E-77 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_02715 bc429a1cb3f0ee7c7152a4f950a93ee8 428 TIGRFAM TIGR00483 EF-1_alpha: translation elongation factor EF-1, subunit alpha 1 427 1.9E-215 T 23-10-2018 IPR004539 Translation elongation factor EF1A, eukaryotic/archaeal GO:0003746|GO:0005525|GO:0005737|GO:0006414 Reactome: R-HSA-156842 A0127_02715 bc429a1cb3f0ee7c7152a4f950a93ee8 428 PRINTS PR00315 GTP-binding elongation factor signature 66 74 1.4E-24 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A0127_02715 bc429a1cb3f0ee7c7152a4f950a93ee8 428 PRINTS PR00315 GTP-binding elongation factor signature 102 113 1.4E-24 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A0127_02715 bc429a1cb3f0ee7c7152a4f950a93ee8 428 PRINTS PR00315 GTP-binding elongation factor signature 86 96 1.4E-24 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A0127_02715 bc429a1cb3f0ee7c7152a4f950a93ee8 428 PRINTS PR00315 GTP-binding elongation factor signature 9 22 1.4E-24 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A0127_02715 bc429a1cb3f0ee7c7152a4f950a93ee8 428 PRINTS PR00315 GTP-binding elongation factor signature 139 148 1.4E-24 T 23-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 A0127_02715 bc429a1cb3f0ee7c7152a4f950a93ee8 428 SUPERFAMILY SSF50447 213 315 2.5E-29 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily A0127_02715 bc429a1cb3f0ee7c7152a4f950a93ee8 428 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 8 190 1.4E-16 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A0127_02715 bc429a1cb3f0ee7c7152a4f950a93ee8 428 Gene3D G3DSA:2.40.30.10 320 425 5.4E-41 T 23-10-2018 A0127_02715 bc429a1cb3f0ee7c7152a4f950a93ee8 428 Pfam PF03144 Elongation factor Tu domain 2 235 306 3.6E-18 T 23-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 A0127_02715 bc429a1cb3f0ee7c7152a4f950a93ee8 428 Gene3D G3DSA:2.40.30.10 216 310 1.6E-41 T 23-10-2018 A0127_02715 bc429a1cb3f0ee7c7152a4f950a93ee8 428 SUPERFAMILY SSF50465 321 424 2.45E-39 T 23-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal A0127_05920 6a085b87b56f5011d3ed6493981ada2b 1198 SUPERFAMILY SSF52540 261 511 3.72E-46 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_05920 6a085b87b56f5011d3ed6493981ada2b 1198 PRINTS PR00379 Intein signature 702 714 8.9E-18 T 23-10-2018 IPR006142 Intein GO:0016539 A0127_05920 6a085b87b56f5011d3ed6493981ada2b 1198 PRINTS PR00379 Intein signature 800 812 8.9E-18 T 23-10-2018 IPR006142 Intein GO:0016539 A0127_05920 6a085b87b56f5011d3ed6493981ada2b 1198 PRINTS PR00379 Intein signature 828 843 8.9E-18 T 23-10-2018 IPR006142 Intein GO:0016539 A0127_05920 6a085b87b56f5011d3ed6493981ada2b 1198 PRINTS PR00379 Intein signature 599 612 8.9E-18 T 23-10-2018 IPR006142 Intein GO:0016539 A0127_05920 6a085b87b56f5011d3ed6493981ada2b 1198 PRINTS PR00379 Intein signature 1011 1028 8.9E-18 T 23-10-2018 IPR006142 Intein GO:0016539 A0127_05920 6a085b87b56f5011d3ed6493981ada2b 1198 Pfam PF14528 LAGLIDADG-like domain 799 876 2.4E-14 T 23-10-2018 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 A0127_05920 6a085b87b56f5011d3ed6493981ada2b 1198 SUPERFAMILY SSF55608 785 892 6.43E-23 T 23-10-2018 IPR027434 Homing endonuclease A0127_05920 6a085b87b56f5011d3ed6493981ada2b 1198 Gene3D G3DSA:3.10.28.10 698 872 1.5E-25 T 23-10-2018 IPR027434 Homing endonuclease A0127_05920 6a085b87b56f5011d3ed6493981ada2b 1198 SMART SM00306 510 636 1.8E-20 T 23-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A0127_05920 6a085b87b56f5011d3ed6493981ada2b 1198 TIGRFAM TIGR01445 intein_Nterm: intein N-terminal splicing region 519 612 2.1E-9 T 23-10-2018 IPR006141 Intein N-terminal splicing region GO:0016539 Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A0127_05920 6a085b87b56f5011d3ed6493981ada2b 1198 Gene3D G3DSA:3.40.50.300 1034 1186 7.3E-35 T 23-10-2018 A0127_05920 6a085b87b56f5011d3ed6493981ada2b 1198 Gene3D G3DSA:3.40.50.300 376 513 9.6E-59 T 23-10-2018 A0127_05920 6a085b87b56f5011d3ed6493981ada2b 1198 Pfam PF14890 Intein splicing domain 532 1032 2.5E-28 T 23-10-2018 A0127_05920 6a085b87b56f5011d3ed6493981ada2b 1198 Gene3D G3DSA:2.170.16.10 960 1033 1.1E-11 T 23-10-2018 A0127_05920 6a085b87b56f5011d3ed6493981ada2b 1198 Gene3D G3DSA:2.170.16.10 514 659 3.9E-28 T 23-10-2018 A0127_05920 6a085b87b56f5011d3ed6493981ada2b 1198 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 1013 1035 2.2E-9 T 23-10-2018 IPR030934 Intein C-terminal splicing region A0127_05920 6a085b87b56f5011d3ed6493981ada2b 1198 SUPERFAMILY SSF51294 517 1035 5.3E-36 T 23-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A0127_05920 6a085b87b56f5011d3ed6493981ada2b 1198 Gene3D G3DSA:3.30.450.380 155 375 4.5E-65 T 23-10-2018 A0127_05920 6a085b87b56f5011d3ed6493981ada2b 1198 Pfam PF00437 Type II/IV secretion system protein 281 513 1.0E-54 T 23-10-2018 IPR001482 Type II/IV secretion system protein A0127_05920 6a085b87b56f5011d3ed6493981ada2b 1198 SMART SM00305 990 1040 2.7E-15 T 23-10-2018 IPR003586 Hint domain C-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A0127_08550 151e4d70f6a1ea597d687ccedf48ab3f 248 SMART SM00986 104 239 3.5E-12 T 23-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A0127_08550 151e4d70f6a1ea597d687ccedf48ab3f 248 Pfam PF03167 Uracil DNA glycosylase superfamily 109 206 1.2E-20 T 23-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A0127_08550 151e4d70f6a1ea597d687ccedf48ab3f 248 Gene3D G3DSA:3.40.470.10 88 242 1.7E-25 T 23-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A0127_08550 151e4d70f6a1ea597d687ccedf48ab3f 248 SUPERFAMILY SSF52141 100 241 8.18E-25 T 23-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A0127_08550 151e4d70f6a1ea597d687ccedf48ab3f 248 SMART SM00987 104 239 3.5E-12 T 23-10-2018 A0127_04355 11bdf9ea037a86cc07ce35735a4bcaaf 300 SUPERFAMILY SSF47413 15 80 1.75E-9 T 23-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A0127_04355 11bdf9ea037a86cc07ce35735a4bcaaf 300 Gene3D G3DSA:3.40.225.10 120 298 7.5E-46 T 23-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily A0127_04355 11bdf9ea037a86cc07ce35735a4bcaaf 300 SUPERFAMILY SSF53639 127 291 1.14E-46 T 23-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily A0127_04355 11bdf9ea037a86cc07ce35735a4bcaaf 300 Gene3D G3DSA:1.10.260.40 9 74 1.7E-7 T 23-10-2018 A0127_04355 11bdf9ea037a86cc07ce35735a4bcaaf 300 Pfam PF10120 Thiamine-phosphate synthase 132 289 3.1E-48 T 23-10-2018 IPR019293 Thiamine-phosphate synthase ThiN GO:0004789 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 A0127_04355 11bdf9ea037a86cc07ce35735a4bcaaf 300 SMART SM00530 19 74 0.0014 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A0127_09485 fc7c72acaef06d9c752cc71ea2e4ef9a 210 Pfam PF12838 4Fe-4S dicluster domain 53 103 8.4E-13 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A0127_09485 fc7c72acaef06d9c752cc71ea2e4ef9a 210 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 89 100 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A0127_09485 fc7c72acaef06d9c752cc71ea2e4ef9a 210 SUPERFAMILY SSF54862 37 133 5.86E-24 T 23-10-2018 A0127_09485 fc7c72acaef06d9c752cc71ea2e4ef9a 210 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 54 65 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A0127_09485 fc7c72acaef06d9c752cc71ea2e4ef9a 210 Gene3D G3DSA:3.30.70.3270 32 189 3.9E-21 T 23-10-2018 A0127_07950 c63286c1c67909c5eadd06284e6a002b 105 Pfam PF00543 Nitrogen regulatory protein P-II 4 97 2.6E-28 T 23-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 A0127_07950 c63286c1c67909c5eadd06284e6a002b 105 SMART SM00938 4 97 8.7E-43 T 23-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 A0127_07950 c63286c1c67909c5eadd06284e6a002b 105 SUPERFAMILY SSF54913 1 104 1.78E-35 T 23-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta A0127_07950 c63286c1c67909c5eadd06284e6a002b 105 PRINTS PR00340 P-II protein signature 75 95 2.4E-23 T 23-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 A0127_07950 c63286c1c67909c5eadd06284e6a002b 105 PRINTS PR00340 P-II protein signature 2 17 2.4E-23 T 23-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 A0127_07950 c63286c1c67909c5eadd06284e6a002b 105 PRINTS PR00340 P-II protein signature 44 67 2.4E-23 T 23-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 A0127_07950 c63286c1c67909c5eadd06284e6a002b 105 Gene3D G3DSA:3.30.70.120 1 105 8.5E-39 T 23-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal A0127_02225 05459e0a188b0eca01b77f751b17acf3 154 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 11 152 30.837 T 23-10-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A0127_02225 05459e0a188b0eca01b77f751b17acf3 154 Gene3D G3DSA:3.40.50.960 3 153 9.5E-60 T 23-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A0127_02225 05459e0a188b0eca01b77f751b17acf3 154 SUPERFAMILY SSF52121 5 152 4.71E-58 T 23-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A0127_02225 05459e0a188b0eca01b77f751b17acf3 154 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 14 149 2.2E-55 T 23-10-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A0127_02225 05459e0a188b0eca01b77f751b17acf3 154 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 15 149 1.2E-51 T 23-10-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A0127_06645 ff60a9f13ec197544284b82b725d007b 409 Pfam PF01943 Polysaccharide biosynthesis protein 9 277 1.0E-23 T 23-10-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 A0127_06645 ff60a9f13ec197544284b82b725d007b 409 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 330 404 1.3E-16 T 23-10-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain A0127_09420 3fa1b43a9bd4bcf907a575d07f6c0227 249 SUPERFAMILY SSF52540 1 245 2.47E-33 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_09420 3fa1b43a9bd4bcf907a575d07f6c0227 249 PIRSF PIRSF005647 1 244 1.9E-64 T 23-10-2018 IPR014433 Nickel insertion ATPase/GTPase (CO dehydrogenase maturation factor), CooC type A0127_09420 3fa1b43a9bd4bcf907a575d07f6c0227 249 Gene3D G3DSA:3.40.50.300 1 244 1.9E-42 T 23-10-2018 A0127_09420 3fa1b43a9bd4bcf907a575d07f6c0227 249 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 3 152 2.4E-12 T 23-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain A0127_09735 5d79b9170ea1b9f9c3b52155c244b15f 94 ProDom PD002841 RIBOSOMAL RIBONUCLEOPROTEIN 60S L44 L44E L41 RESISTANCE 50S ANTIBIOTIC CYCLOHEXIMIDE 9 93 6.0E-43 T 23-10-2018 IPR000552 Ribosomal protein L44e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_09735 5d79b9170ea1b9f9c3b52155c244b15f 94 Pfam PF00935 Ribosomal protein L44 16 92 2.0E-26 T 23-10-2018 IPR000552 Ribosomal protein L44e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_09735 5d79b9170ea1b9f9c3b52155c244b15f 94 Gene3D G3DSA:3.10.450.80 1 93 4.3E-31 T 23-10-2018 A0127_09735 5d79b9170ea1b9f9c3b52155c244b15f 94 SUPERFAMILY SSF57829 1 93 2.87E-29 T 23-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 A0127_09735 5d79b9170ea1b9f9c3b52155c244b15f 94 Hamap MF_01476 50S ribosomal protein L44e [rpl44e]. 1 92 25.054 T 23-10-2018 IPR000552 Ribosomal protein L44e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_09735 5d79b9170ea1b9f9c3b52155c244b15f 94 ProSitePatterns PS01172 Ribosomal protein L44e signature. 60 71 - T 23-10-2018 IPR000552 Ribosomal protein L44e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_01670 0d84e499f2854eae76ca0e2ca6c7aebd 174 Gene3D G3DSA:1.20.1260.10 12 161 2.2E-48 T 23-10-2018 IPR012347 Ferritin-like A0127_01670 0d84e499f2854eae76ca0e2ca6c7aebd 174 SUPERFAMILY SSF47240 12 165 1.62E-30 T 23-10-2018 IPR009078 Ferritin-like superfamily A0127_01670 0d84e499f2854eae76ca0e2ca6c7aebd 174 Pfam PF02915 Rubrerythrin 22 157 9.1E-32 T 23-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 A0127_08785 2acad512257d804eced9f09f34d61080 419 SUPERFAMILY SSF102114 111 313 1.44E-38 T 23-10-2018 A0127_08785 2acad512257d804eced9f09f34d61080 419 Pfam PF04055 Radical SAM superfamily 123 287 8.1E-28 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A0127_08785 2acad512257d804eced9f09f34d61080 419 Gene3D G3DSA:3.20.20.70 113 359 1.5E-37 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A0127_08785 2acad512257d804eced9f09f34d61080 419 SMART SM00729 115 333 1.4E-13 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A0127_00670 444d133a2b13b8583c3a5b789153f6f0 288 Pfam PF00491 Arginase family 24 279 4.5E-63 T 23-10-2018 IPR006035 Ureohydrolase GO:0046872 A0127_00670 444d133a2b13b8583c3a5b789153f6f0 288 PIRSF PIRSF036979 1 286 5.9E-84 T 23-10-2018 IPR006035 Ureohydrolase GO:0046872 A0127_00670 444d133a2b13b8583c3a5b789153f6f0 288 SUPERFAMILY SSF52768 16 285 5.94E-73 T 23-10-2018 IPR023696 Ureohydrolase domain superfamily A0127_00670 444d133a2b13b8583c3a5b789153f6f0 288 TIGRFAM TIGR01230 agmatinase: agmatinase 19 278 4.0E-69 T 23-10-2018 IPR005925 Agmatinase-related KEGG: 00330+3.5.3.11|MetaCyc: PWY-40|MetaCyc: PWY-6305|Reactome: R-HSA-351143 A0127_00670 444d133a2b13b8583c3a5b789153f6f0 288 Gene3D G3DSA:3.40.800.10 5 287 2.9E-75 T 23-10-2018 A0127_04995 fe9c115f2491907f33ba9f55fe9c7dfd 185 TIGRFAM TIGR02175 PorC_KorC: 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate family 1 180 4.9E-80 T 23-10-2018 IPR011894 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate GO:0016625|GO:0055114 A0127_04995 fe9c115f2491907f33ba9f55fe9c7dfd 185 Gene3D G3DSA:3.40.920.10 1 182 2.6E-73 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 A0127_04995 fe9c115f2491907f33ba9f55fe9c7dfd 185 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 10 177 1.3E-44 T 23-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 A0127_04995 fe9c115f2491907f33ba9f55fe9c7dfd 185 SUPERFAMILY SSF53323 1 179 4.97E-58 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 A0127_00560 0e8f9d79bc6b8f6ac3a1b6b1776e5c34 206 Gene3D G3DSA:1.20.58.2140 3 202 5.2E-63 T 23-10-2018 A0127_00560 0e8f9d79bc6b8f6ac3a1b6b1776e5c34 206 SUPERFAMILY SSF74784 1 182 4.71E-35 T 23-10-2018 IPR036081 Translin superfamily GO:0043565 Reactome: R-HSA-426486 A0127_00815 d0a366dc8f1dfcfd36dc4c2704dbf19b 311 Pfam PF01699 Sodium/calcium exchanger protein 10 143 6.7E-21 T 23-10-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 A0127_00815 d0a366dc8f1dfcfd36dc4c2704dbf19b 311 Pfam PF01699 Sodium/calcium exchanger protein 169 305 9.9E-22 T 23-10-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 A0127_00815 d0a366dc8f1dfcfd36dc4c2704dbf19b 311 TIGRFAM TIGR00367 TIGR00367: K+-dependent Na+/Ca+ exchanger homolog 8 301 1.3E-57 T 23-10-2018 IPR004481 Sodium/potassium/calcium exchanger Reactome: R-HSA-425561 A0127_00815 d0a366dc8f1dfcfd36dc4c2704dbf19b 311 Gene3D G3DSA:1.20.58.1130 11 199 1.8E-75 T 23-10-2018 A0127_00815 d0a366dc8f1dfcfd36dc4c2704dbf19b 311 Gene3D G3DSA:1.20.1420.30 37 298 1.8E-75 T 23-10-2018 A0127_09100 d38c91e7642051501174a86f84957cf1 94 Gene3D G3DSA:3.30.1360.10 1 94 1.2E-34 T 23-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A0127_09100 d38c91e7642051501174a86f84957cf1 94 ProSitePatterns PS01154 RNA polymerases L / 13 to 16 Kd subunits signature. 17 48 - T 23-10-2018 IPR008193 DNA-directed RNA polymerase Rpb11, 13-16kDa subunit, conserved site GO:0003677|GO:0003899|GO:0006351 A0127_09100 d38c91e7642051501174a86f84957cf1 94 Pfam PF13656 RNA polymerase Rpb3/Rpb11 dimerisation domain 13 86 2.0E-20 T 23-10-2018 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 A0127_09100 d38c91e7642051501174a86f84957cf1 94 SUPERFAMILY SSF55257 1 94 4.32E-24 T 23-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A0127_09100 d38c91e7642051501174a86f84957cf1 94 Hamap MF_00261 DNA-directed RNA polymerase subunit L [rpoL]. 1 89 19.987 T 23-10-2018 IPR022905 DNA-directed RNA polymerase subunit L (Rpo11) GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A0127_09885 a7a47d8116f0c4043af522bb0101970e 383 Pfam PF13186 Iron-sulfur cluster-binding domain 260 338 2.8E-17 T 23-10-2018 IPR023885 4Fe4S-binding SPASM domain A0127_09885 a7a47d8116f0c4043af522bb0101970e 383 SMART SM00729 29 225 0.0047 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A0127_09885 a7a47d8116f0c4043af522bb0101970e 383 TIGRFAM TIGR04317 W_rSAM_matur: tungsten cofactor oxidoreducase radical SAM maturase 27 373 1.3E-154 T 23-10-2018 IPR027604 Tungsten cofactor oxidoreducase radical SAM maturase A0127_09885 a7a47d8116f0c4043af522bb0101970e 383 PIRSF PIRSF037420 22 214 2.2E-26 T 23-10-2018 IPR017200 Coenzyme PQQ synthesis protein E A0127_09885 a7a47d8116f0c4043af522bb0101970e 383 PIRSF PIRSF037420 290 371 1.7E-7 T 23-10-2018 IPR017200 Coenzyme PQQ synthesis protein E A0127_09885 a7a47d8116f0c4043af522bb0101970e 383 SUPERFAMILY SSF102114 30 343 9.16E-57 T 23-10-2018 A0127_09885 a7a47d8116f0c4043af522bb0101970e 383 Pfam PF04055 Radical SAM superfamily 33 198 4.3E-17 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A0127_09885 a7a47d8116f0c4043af522bb0101970e 383 Pfam PF13394 4Fe-4S single cluster domain 36 121 3.2E-7 T 23-10-2018 A0127_00765 e6913ec7910ba8ff9b5fe4d809496091 794 PRINTS PR00344 Bacterial sensor protein C-terminal signature 560 574 3.6E-14 T 23-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A0127_00765 e6913ec7910ba8ff9b5fe4d809496091 794 PRINTS PR00344 Bacterial sensor protein C-terminal signature 618 636 3.6E-14 T 23-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A0127_00765 e6913ec7910ba8ff9b5fe4d809496091 794 PRINTS PR00344 Bacterial sensor protein C-terminal signature 642 655 3.6E-14 T 23-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A0127_00765 e6913ec7910ba8ff9b5fe4d809496091 794 PRINTS PR00344 Bacterial sensor protein C-terminal signature 602 612 3.6E-14 T 23-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 A0127_00765 e6913ec7910ba8ff9b5fe4d809496091 794 Pfam PF02895 Signal transducing histidine kinase, homodimeric domain 411 470 2.7E-16 T 23-10-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 A0127_00765 e6913ec7910ba8ff9b5fe4d809496091 794 Gene3D G3DSA:3.30.70.1110 283 366 2.7E-8 T 23-10-2018 IPR037052 Chemotaxis protein CheA, P2 response regulator-binding domain superfamily A0127_00765 e6913ec7910ba8ff9b5fe4d809496091 794 Gene3D G3DSA:3.30.70.1110 174 257 3.7E-13 T 23-10-2018 IPR037052 Chemotaxis protein CheA, P2 response regulator-binding domain superfamily A0127_00765 e6913ec7910ba8ff9b5fe4d809496091 794 Gene3D G3DSA:2.30.30.40 658 783 3.4E-40 T 23-10-2018 A0127_00765 e6913ec7910ba8ff9b5fe4d809496091 794 SUPERFAMILY SSF55052 286 366 1.23E-13 T 23-10-2018 IPR035891 CheY-binding domain of CheA A0127_00765 e6913ec7910ba8ff9b5fe4d809496091 794 Gene3D G3DSA:2.40.50.180 681 742 3.4E-40 T 23-10-2018 A0127_00765 e6913ec7910ba8ff9b5fe4d809496091 794 Pfam PF01584 CheW-like domain 662 788 3.7E-27 T 23-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 A0127_00765 e6913ec7910ba8ff9b5fe4d809496091 794 SMART SM00260 650 787 1.6E-41 T 23-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 A0127_00765 e6913ec7910ba8ff9b5fe4d809496091 794 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 520 655 4.8E-18 T 23-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A0127_00765 e6913ec7910ba8ff9b5fe4d809496091 794 SMART SM00073 4 107 9.1E-25 T 23-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 A0127_00765 e6913ec7910ba8ff9b5fe4d809496091 794 Gene3D G3DSA:3.30.565.10 471 657 2.0E-61 T 23-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A0127_00765 e6913ec7910ba8ff9b5fe4d809496091 794 Gene3D G3DSA:1.10.287.560 410 470 2.1E-19 T 23-10-2018 IPR037006 Histidine kinase CheA-like, homodimeric domain superfamily GO:0000155|GO:0006935 A0127_00765 e6913ec7910ba8ff9b5fe4d809496091 794 SUPERFAMILY SSF55052 175 256 4.71E-17 T 23-10-2018 IPR035891 CheY-binding domain of CheA A0127_00765 e6913ec7910ba8ff9b5fe4d809496091 794 SUPERFAMILY SSF47226 3 134 1.65E-28 T 23-10-2018 IPR036641 HPT domain superfamily GO:0000160 A0127_00765 e6913ec7910ba8ff9b5fe4d809496091 794 Pfam PF07194 P2 response regulator binding domain 176 256 2.5E-18 T 23-10-2018 IPR010808 Chemotaxis protein CheA, P2 response regulator-binding GO:0000155|GO:0000160|GO:0004673|GO:0006928 A0127_00765 e6913ec7910ba8ff9b5fe4d809496091 794 Pfam PF07194 P2 response regulator binding domain 287 365 1.1E-14 T 23-10-2018 IPR010808 Chemotaxis protein CheA, P2 response regulator-binding GO:0000155|GO:0000160|GO:0004673|GO:0006928 A0127_00765 e6913ec7910ba8ff9b5fe4d809496091 794 Gene3D G3DSA:1.20.120.160 1 147 1.2E-33 T 23-10-2018 IPR036641 HPT domain superfamily GO:0000160 A0127_00765 e6913ec7910ba8ff9b5fe4d809496091 794 SUPERFAMILY SSF47384 411 471 5.89E-16 T 23-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 A0127_00765 e6913ec7910ba8ff9b5fe4d809496091 794 SUPERFAMILY SSF50341 657 787 1.18E-34 T 23-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 A0127_00765 e6913ec7910ba8ff9b5fe4d809496091 794 SMART SM01231 410 470 2.8E-20 T 23-10-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 A0127_00765 e6913ec7910ba8ff9b5fe4d809496091 794 SMART SM00387 515 658 7.2E-30 T 23-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A0127_00765 e6913ec7910ba8ff9b5fe4d809496091 794 SUPERFAMILY SSF55874 474 655 9.43E-45 T 23-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A0127_00765 e6913ec7910ba8ff9b5fe4d809496091 794 Pfam PF01627 Hpt domain 6 111 3.3E-21 T 23-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 A0127_03785 f6ced2745b132f3ba3532aa2b2d2c319 185 SMART SM00471 26 144 1.2E-12 T 23-10-2018 IPR003607 HD/PDEase domain A0127_03785 f6ced2745b132f3ba3532aa2b2d2c319 185 Pfam PF13023 HD domain 9 164 7.7E-34 T 23-10-2018 IPR006674 HD domain A0127_03785 f6ced2745b132f3ba3532aa2b2d2c319 185 Gene3D G3DSA:1.10.3210.10 1 182 3.3E-63 T 23-10-2018 A0127_03785 f6ced2745b132f3ba3532aa2b2d2c319 185 SUPERFAMILY SSF109604 2 172 4.11E-43 T 23-10-2018 A0127_03590 0c25b547b4a334e1a6b39139941146c8 177 SUPERFAMILY SSF75217 1 174 2.43E-69 T 23-10-2018 IPR029028 Alpha/beta knot methyltransferases A0127_03590 0c25b547b4a334e1a6b39139941146c8 177 PIRSF PIRSF016123 1 177 1.4E-85 T 23-10-2018 IPR002845 tRNA ribose 2'-O-methyltransferase, aTrm56 GO:0002128|GO:0005737|GO:0008175 A0127_03590 0c25b547b4a334e1a6b39139941146c8 177 Pfam PF01994 tRNA ribose 2'-O-methyltransferase, aTrm56 54 173 1.8E-51 T 23-10-2018 IPR002845 tRNA ribose 2'-O-methyltransferase, aTrm56 GO:0002128|GO:0005737|GO:0008175 A0127_03590 0c25b547b4a334e1a6b39139941146c8 177 ProDom PD016584 UPF0106 MK0803 MM0086 METAL MA3241 UNCHARACTERIZED DOMAIN TA0931 APE2006 ST0333 54 177 5.0E-64 T 23-10-2018 IPR002845 tRNA ribose 2'-O-methyltransferase, aTrm56 GO:0002128|GO:0005737|GO:0008175 A0127_03590 0c25b547b4a334e1a6b39139941146c8 177 Gene3D G3DSA:3.40.1280.10 1 177 5.8E-81 T 23-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal A0127_03590 0c25b547b4a334e1a6b39139941146c8 177 Hamap MF_00077 tRNA (cytidine(56)-2'-O)-methyltransferase. 1 176 44.159 T 23-10-2018 IPR002845 tRNA ribose 2'-O-methyltransferase, aTrm56 GO:0002128|GO:0005737|GO:0008175 A0127_03580 78fe7cb6aee126c678d7f1af842908d1 256 Gene3D G3DSA:2.40.30.90 161 256 1.8E-33 T 23-10-2018 IPR023227 S-adenosyl-l-methionine hydroxide adenosyltransferase, C-terminal A0127_03580 78fe7cb6aee126c678d7f1af842908d1 256 Pfam PF01887 S-adenosyl-l-methionine hydroxide adenosyltransferase 2 252 2.4E-77 T 23-10-2018 IPR002747 SAM-dependent chlorinase/fluorinase A0127_03580 78fe7cb6aee126c678d7f1af842908d1 256 SUPERFAMILY SSF101852 163 254 9.42E-26 T 23-10-2018 IPR023227 S-adenosyl-l-methionine hydroxide adenosyltransferase, C-terminal A0127_03580 78fe7cb6aee126c678d7f1af842908d1 256 Gene3D G3DSA:3.40.50.10790 1 160 2.9E-61 T 23-10-2018 IPR023228 S-adenosyl-l-methionine hydroxide adenosyltransferase, N-terminal A0127_03580 78fe7cb6aee126c678d7f1af842908d1 256 SUPERFAMILY SSF102522 1 161 8.76E-56 T 23-10-2018 IPR023228 S-adenosyl-l-methionine hydroxide adenosyltransferase, N-terminal A0127_03580 78fe7cb6aee126c678d7f1af842908d1 256 PIRSF PIRSF006779 1 256 1.7E-77 T 23-10-2018 IPR002747 SAM-dependent chlorinase/fluorinase A0127_00445 303cdbaa18971a90c07c365652cbb4c9 244 Gene3D G3DSA:3.30.1490.20 40 117 1.5E-93 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 A0127_00445 303cdbaa18971a90c07c365652cbb4c9 244 SUPERFAMILY SSF56059 21 236 4.24E-47 T 23-10-2018 A0127_00445 303cdbaa18971a90c07c365652cbb4c9 244 Pfam PF13549 ATP-grasp domain 14 234 7.7E-82 T 23-10-2018 A0127_00445 303cdbaa18971a90c07c365652cbb4c9 244 Gene3D G3DSA:3.30.470.20 19 234 1.5E-93 T 23-10-2018 A0127_03755 18904a1190c673dc246d354a98c5571a 421 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 142 416 2.0E-28 T 23-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 A0127_03755 18904a1190c673dc246d354a98c5571a 421 ProSitePatterns PS00739 S-adenosyl-L-homocysteine hydrolase signature 2. 210 226 - T 23-10-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 A0127_03755 18904a1190c673dc246d354a98c5571a 421 Hamap MF_00563 Adenosylhomocysteinase [ahcY]. 2 421 50.421 T 23-10-2018 IPR034373 Adenosylhomocysteinase GO:0004013|GO:0019510|GO:0051287 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-2408508|Reactome: R-HSA-5578997 A0127_03755 18904a1190c673dc246d354a98c5571a 421 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 6 139 4.4E-35 T 23-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 A0127_03755 18904a1190c673dc246d354a98c5571a 421 ProSitePatterns PS00738 S-adenosyl-L-homocysteine hydrolase signature 1. 78 92 - T 23-10-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 A0127_03755 18904a1190c673dc246d354a98c5571a 421 SUPERFAMILY SSF51735 188 350 1.14E-68 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A0127_03755 18904a1190c673dc246d354a98c5571a 421 Gene3D G3DSA:3.40.50.1480 9 410 8.5E-178 T 23-10-2018 A0127_03755 18904a1190c673dc246d354a98c5571a 421 Pfam PF00670 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 188 348 3.0E-50 T 23-10-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 A0127_03755 18904a1190c673dc246d354a98c5571a 421 SMART SM00997 188 349 3.0E-110 T 23-10-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 A0127_03755 18904a1190c673dc246d354a98c5571a 421 Gene3D G3DSA:3.40.50.720 190 349 8.5E-178 T 23-10-2018 A0127_03755 18904a1190c673dc246d354a98c5571a 421 SMART SM00996 6 420 5.1E-141 T 23-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 A0127_03755 18904a1190c673dc246d354a98c5571a 421 TIGRFAM TIGR00936 ahcY: adenosylhomocysteinase 7 421 5.1E-210 T 23-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 A0127_03755 18904a1190c673dc246d354a98c5571a 421 PIRSF PIRSF001109 1 421 1.4E-196 T 23-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 A0127_03755 18904a1190c673dc246d354a98c5571a 421 SUPERFAMILY SSF52283 5 421 2.38E-102 T 23-10-2018 A0127_01675 ba9c58583505fdc070218b1b8522f9ab 117 Pfam PF01883 Iron-sulfur cluster assembly protein 15 54 6.6E-6 T 23-10-2018 IPR002744 MIP18 family-like A0127_01675 ba9c58583505fdc070218b1b8522f9ab 117 SUPERFAMILY SSF117916 16 59 2.42E-5 T 23-10-2018 IPR034904 Fe-S cluster assembly domain superfamily A0127_03210 7eeeb64cefc14e925abffc548a7c01fc 151 SUPERFAMILY SSF54909 66 151 8.98E-23 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel A0127_03210 7eeeb64cefc14e925abffc548a7c01fc 151 SUPERFAMILY SSF46785 6 66 2.19E-17 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A0127_03210 7eeeb64cefc14e925abffc548a7c01fc 151 Gene3D G3DSA:1.10.10.10 4 56 4.6E-23 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A0127_03210 7eeeb64cefc14e925abffc548a7c01fc 151 Gene3D G3DSA:3.30.70.920 58 151 8.0E-29 T 23-10-2018 A0127_03210 7eeeb64cefc14e925abffc548a7c01fc 151 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 22 33 3.9E-17 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A0127_03210 7eeeb64cefc14e925abffc548a7c01fc 151 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 6 22 3.9E-17 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A0127_03210 7eeeb64cefc14e925abffc548a7c01fc 151 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 33 52 3.9E-17 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A0127_03210 7eeeb64cefc14e925abffc548a7c01fc 151 SMART SM00344 6 112 1.4E-47 T 23-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A0127_03210 7eeeb64cefc14e925abffc548a7c01fc 151 Pfam PF01037 Lrp/AsnC ligand binding domain 72 141 8.3E-19 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A0127_03210 7eeeb64cefc14e925abffc548a7c01fc 151 Pfam PF13404 AsnC-type helix-turn-helix domain 6 47 1.2E-15 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A0127_03295 3b763ec171a3e7dcd1270ccd53712a82 98 Pfam PF04324 BFD-like [2Fe-2S] binding domain 10 62 9.1E-14 T 23-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain A0127_03295 3b763ec171a3e7dcd1270ccd53712a82 98 Gene3D G3DSA:1.10.10.1100 1 71 7.9E-23 T 23-10-2018 A0127_06580 9caa26b789873c4f3be9594e90586af0 185 Gene3D G3DSA:2.60.120.10 3 184 2.0E-77 T 23-10-2018 IPR014710 RmlC-like jelly roll fold A0127_06580 9caa26b789873c4f3be9594e90586af0 185 TIGRFAM TIGR01221 rmlC: dTDP-4-dehydrorhamnose 3,5-epimerase 5 178 1.0E-86 T 23-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 A0127_06580 9caa26b789873c4f3be9594e90586af0 185 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 8 177 9.2E-77 T 23-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 A0127_06580 9caa26b789873c4f3be9594e90586af0 185 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 3 177 1.0E-91 T 23-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 A0127_06580 9caa26b789873c4f3be9594e90586af0 185 SUPERFAMILY SSF51182 3 181 3.03E-79 T 23-10-2018 IPR011051 RmlC-like cupin domain superfamily A0127_05840 422c634832d0474adc51117cc02b41ba 109 Pfam PF01934 Protein of unknown function DUF86 12 106 1.5E-29 T 23-10-2018 IPR008201 Protein of unknown function DUF86 A0127_06045 289cd6542a66ac48ccd3d2d24e7d2299 323 PIRSF PIRSF004976 1 317 9.0E-113 T 23-10-2018 IPR035107 tRNA thiolation protein, TtcA/Ctu1 type GO:0008033 Reactome: R-HSA-6782315 A0127_06045 289cd6542a66ac48ccd3d2d24e7d2299 323 SUPERFAMILY SSF52402 25 257 1.04E-54 T 23-10-2018 A0127_06045 289cd6542a66ac48ccd3d2d24e7d2299 323 Pfam PF01171 PP-loop family 50 228 9.6E-15 T 23-10-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 A0127_06045 289cd6542a66ac48ccd3d2d24e7d2299 323 ProSitePatterns PS01263 Uncharacterized protein family UPF0021 signature. 22 59 - T 23-10-2018 IPR020554 Uncharacterised protein family UPF0021, conserved site A0127_06045 289cd6542a66ac48ccd3d2d24e7d2299 323 TIGRFAM TIGR00269 TIGR00269: TIGR00269 family protein 204 305 7.6E-38 T 23-10-2018 IPR000541 Cytoplasmic tRNA 2-thiolation protein 1 GO:0000049|GO:0002098|GO:0034227 Reactome: R-HSA-6782315 A0127_06045 289cd6542a66ac48ccd3d2d24e7d2299 323 Gene3D G3DSA:3.40.50.620 1 319 4.4E-88 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A0127_07400 08a0d8a93d56cc1389a374d802af637b 447 Gene3D G3DSA:3.90.550.10 62 298 2.8E-38 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A0127_07400 08a0d8a93d56cc1389a374d802af637b 447 Pfam PF13641 Glycosyltransferase like family 2 77 307 7.7E-27 T 23-10-2018 A0127_07400 08a0d8a93d56cc1389a374d802af637b 447 SUPERFAMILY SSF53448 70 349 5.16E-50 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A0127_09020 0d0686d911207d79b5b67b80c5d9e341 295 Gene3D G3DSA:3.90.230.10 9 286 9.4E-108 T 23-10-2018 A0127_09020 0d0686d911207d79b5b67b80c5d9e341 295 Hamap MF_01975 Methionine aminopeptidase [map]. 4 295 47.205 T 23-10-2018 IPR028595 Methionine aminopeptidase, archaeal GO:0004177|GO:0006508 MetaCyc: PWY-7799|MetaCyc: PWY-7800 A0127_09020 0d0686d911207d79b5b67b80c5d9e341 295 ProSitePatterns PS01202 Methionine aminopeptidase subfamily 2 signature. 78 94 - T 23-10-2018 IPR018349 Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site MetaCyc: PWY-7799|MetaCyc: PWY-7800 A0127_09020 0d0686d911207d79b5b67b80c5d9e341 295 Gene3D G3DSA:1.10.10.10 196 272 9.4E-108 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A0127_09020 0d0686d911207d79b5b67b80c5d9e341 295 SUPERFAMILY SSF55920 3 295 6.41E-67 T 23-10-2018 IPR036005 Creatinase/aminopeptidase-like A0127_09020 0d0686d911207d79b5b67b80c5d9e341 295 Pfam PF00557 Metallopeptidase family M24 7 287 3.1E-44 T 23-10-2018 IPR000994 Peptidase M24 A0127_09020 0d0686d911207d79b5b67b80c5d9e341 295 TIGRFAM TIGR00501 met_pdase_II: methionine aminopeptidase, type II 2 295 5.1E-117 T 23-10-2018 IPR002468 Peptidase M24A, methionine aminopeptidase, subfamily 2 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800|Reactome: R-HSA-2514859 A0127_09020 0d0686d911207d79b5b67b80c5d9e341 295 PRINTS PR00599 Methionine aminopeptidase-1 signature 145 157 9.7E-17 T 23-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 A0127_09020 0d0686d911207d79b5b67b80c5d9e341 295 PRINTS PR00599 Methionine aminopeptidase-1 signature 53 66 9.7E-17 T 23-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 A0127_09020 0d0686d911207d79b5b67b80c5d9e341 295 PRINTS PR00599 Methionine aminopeptidase-1 signature 177 189 9.7E-17 T 23-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 A0127_09020 0d0686d911207d79b5b67b80c5d9e341 295 PRINTS PR00599 Methionine aminopeptidase-1 signature 78 94 9.7E-17 T 23-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 A0127_09020 0d0686d911207d79b5b67b80c5d9e341 295 SUPERFAMILY SSF46785 196 271 4.22E-18 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A0127_06835 29321b0a88caa88822d96ecfa09899e7 284 PIRSF PIRSF006816 1 258 7.1E-44 T 23-10-2018 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 A0127_06835 29321b0a88caa88822d96ecfa09899e7 284 SUPERFAMILY SSF52343 117 251 1.92E-14 T 23-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A0127_06835 29321b0a88caa88822d96ecfa09899e7 284 Gene3D G3DSA:3.40.50.80 101 206 1.5E-15 T 23-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A0127_06835 29321b0a88caa88822d96ecfa09899e7 284 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 216 252 3.6E-12 T 23-10-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain A0127_06835 29321b0a88caa88822d96ecfa09899e7 284 Gene3D G3DSA:2.40.30.10 2 93 7.6E-13 T 23-10-2018 A0127_06835 29321b0a88caa88822d96ecfa09899e7 284 SUPERFAMILY SSF63380 4 93 1.07E-13 T 23-10-2018 IPR017938 Riboflavin synthase-like beta-barrel A0127_07435 dafc2b886f8ddcddb07371faab189456 387 Gene3D G3DSA:1.20.1250.20 4 195 1.9E-13 T 23-10-2018 A0127_07435 dafc2b886f8ddcddb07371faab189456 387 Gene3D G3DSA:1.20.1250.20 196 381 1.0E-6 T 23-10-2018 A0127_07435 dafc2b886f8ddcddb07371faab189456 387 SUPERFAMILY SSF103473 5 376 3.92E-27 T 23-10-2018 IPR036259 MFS transporter superfamily A0127_07435 dafc2b886f8ddcddb07371faab189456 387 Pfam PF07690 Major Facilitator Superfamily 13 306 1.0E-14 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A0127_00245 d9037655426f7291258c1f0e062b7e07 331 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 183 197 1.0E-6 T 23-10-2018 A0127_00245 d9037655426f7291258c1f0e062b7e07 331 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 248 260 1.0E-6 T 23-10-2018 A0127_00245 d9037655426f7291258c1f0e062b7e07 331 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 270 294 1.0E-6 T 23-10-2018 A0127_00245 d9037655426f7291258c1f0e062b7e07 331 SUPERFAMILY SSF53335 141 293 1.35E-28 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A0127_00245 d9037655426f7291258c1f0e062b7e07 331 SUPERFAMILY SSF143437 42 133 2.96E-7 T 23-10-2018 A0127_00245 d9037655426f7291258c1f0e062b7e07 331 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 251 257 - T 23-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 A0127_00245 d9037655426f7291258c1f0e062b7e07 331 Gene3D G3DSA:3.40.50.150 153 331 4.4E-32 T 23-10-2018 A0127_00245 d9037655426f7291258c1f0e062b7e07 331 TIGRFAM TIGR01177 TIGR01177: putative methyltransferase, TIGR01177 family 3 328 2.1E-100 T 23-10-2018 IPR005885 tRNA guanine(10)-N2-dimethyltransferase GO:0004809|GO:0030488 A0127_00245 d9037655426f7291258c1f0e062b7e07 331 Pfam PF02926 THUMP domain 17 133 1.9E-9 T 23-10-2018 IPR004114 THUMP domain GO:0003723 A0127_00245 d9037655426f7291258c1f0e062b7e07 331 SMART SM00981 56 141 2.1E-5 T 23-10-2018 IPR004114 THUMP domain GO:0003723 A0127_00245 d9037655426f7291258c1f0e062b7e07 331 Pfam PF01170 Putative RNA methylase family UPF0020 156 299 3.4E-25 T 23-10-2018 IPR000241 Putative RNA methylase domain A0127_02295 94db01d4352c1fdf1e40174e7a190343 476 Pfam PF09190 DALR domain 356 415 1.7E-16 T 23-10-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 A0127_02295 94db01d4352c1fdf1e40174e7a190343 476 SMART SM00840 356 417 1.9E-15 T 23-10-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 A0127_02295 94db01d4352c1fdf1e40174e7a190343 476 SUPERFAMILY SSF47323 316 473 1.9E-34 T 23-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A0127_02295 94db01d4352c1fdf1e40174e7a190343 476 Gene3D G3DSA:3.40.50.620 1 305 7.7E-151 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A0127_02295 94db01d4352c1fdf1e40174e7a190343 476 Gene3D G3DSA:1.20.120.640 306 473 9.4E-38 T 23-10-2018 A0127_02295 94db01d4352c1fdf1e40174e7a190343 476 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 3 473 3.7E-182 T 23-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 A0127_02295 94db01d4352c1fdf1e40174e7a190343 476 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 16 314 2.4E-138 T 23-10-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 A0127_02295 94db01d4352c1fdf1e40174e7a190343 476 SUPERFAMILY SSF52374 4 314 2.2E-112 T 23-10-2018 A0127_02295 94db01d4352c1fdf1e40174e7a190343 476 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 222 243 2.9E-30 T 23-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 A0127_02295 94db01d4352c1fdf1e40174e7a190343 476 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 191 209 2.9E-30 T 23-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 A0127_02295 94db01d4352c1fdf1e40174e7a190343 476 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 26 37 2.9E-30 T 23-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 A0127_02295 94db01d4352c1fdf1e40174e7a190343 476 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 62 71 2.9E-30 T 23-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 A0127_02295 94db01d4352c1fdf1e40174e7a190343 476 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 3 474 39.902 T 23-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 A0127_01985 bd97e8a59296aa15e18dc83df41e0ff3 346 TIGRFAM TIGR01370 TIGR01370: extracellular protein 48 339 5.0E-118 T 23-10-2018 IPR016063 Extracellular protein A0127_01985 bd97e8a59296aa15e18dc83df41e0ff3 346 Gene3D G3DSA:3.20.20.70 56 346 6.0E-111 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A0127_01985 bd97e8a59296aa15e18dc83df41e0ff3 346 SUPERFAMILY SSF51445 69 329 8.75E-45 T 23-10-2018 IPR017853 Glycoside hydrolase superfamily A0127_01985 bd97e8a59296aa15e18dc83df41e0ff3 346 PRINTS PR01545 Thermotoga maritima hypothetical protein TM1410 signature 163 181 5.6E-68 T 23-10-2018 IPR016062 Hypothetical protein TM1410-related A0127_01985 bd97e8a59296aa15e18dc83df41e0ff3 346 PRINTS PR01545 Thermotoga maritima hypothetical protein TM1410 signature 216 228 5.6E-68 T 23-10-2018 IPR016062 Hypothetical protein TM1410-related A0127_01985 bd97e8a59296aa15e18dc83df41e0ff3 346 PRINTS PR01545 Thermotoga maritima hypothetical protein TM1410 signature 144 161 5.6E-68 T 23-10-2018 IPR016062 Hypothetical protein TM1410-related A0127_01985 bd97e8a59296aa15e18dc83df41e0ff3 346 PRINTS PR01545 Thermotoga maritima hypothetical protein TM1410 signature 235 249 5.6E-68 T 23-10-2018 IPR016062 Hypothetical protein TM1410-related A0127_01985 bd97e8a59296aa15e18dc83df41e0ff3 346 PRINTS PR01545 Thermotoga maritima hypothetical protein TM1410 signature 181 200 5.6E-68 T 23-10-2018 IPR016062 Hypothetical protein TM1410-related A0127_01985 bd97e8a59296aa15e18dc83df41e0ff3 346 PRINTS PR01545 Thermotoga maritima hypothetical protein TM1410 signature 317 329 5.6E-68 T 23-10-2018 IPR016062 Hypothetical protein TM1410-related A0127_01985 bd97e8a59296aa15e18dc83df41e0ff3 346 PRINTS PR01545 Thermotoga maritima hypothetical protein TM1410 signature 121 140 5.6E-68 T 23-10-2018 IPR016062 Hypothetical protein TM1410-related A0127_01985 bd97e8a59296aa15e18dc83df41e0ff3 346 PRINTS PR01545 Thermotoga maritima hypothetical protein TM1410 signature 89 102 5.6E-68 T 23-10-2018 IPR016062 Hypothetical protein TM1410-related A0127_01985 bd97e8a59296aa15e18dc83df41e0ff3 346 PRINTS PR01545 Thermotoga maritima hypothetical protein TM1410 signature 75 88 5.6E-68 T 23-10-2018 IPR016062 Hypothetical protein TM1410-related A0127_01985 bd97e8a59296aa15e18dc83df41e0ff3 346 PRINTS PR01545 Thermotoga maritima hypothetical protein TM1410 signature 290 300 5.6E-68 T 23-10-2018 IPR016062 Hypothetical protein TM1410-related A0127_01985 bd97e8a59296aa15e18dc83df41e0ff3 346 Pfam PF03537 Glycoside-hydrolase family GH114 74 329 1.3E-32 T 23-10-2018 IPR004352 Glycoside-hydrolase family GH114, TIM-barrel domain A0127_07315 42c9208d0a511c38da587f16d035aaaa 914 TIGRFAM TIGR03683 A-tRNA_syn_arch: alanine--tRNA ligase 4 912 0.0 T 23-10-2018 IPR022429 Alanine-tRNA ligase, archaea GO:0000166|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 A0127_07315 42c9208d0a511c38da587f16d035aaaa 914 SUPERFAMILY SSF55186 604 753 2.49E-48 T 23-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 A0127_07315 42c9208d0a511c38da587f16d035aaaa 914 Pfam PF02272 DHHA1 domain 783 912 1.2E-18 T 23-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 A0127_07315 42c9208d0a511c38da587f16d035aaaa 914 Gene3D G3DSA:3.30.930.10 1 260 6.2E-114 T 23-10-2018 A0127_07315 42c9208d0a511c38da587f16d035aaaa 914 Hamap MF_00036_A Alanine--tRNA ligase [alaS]. 4 910 24.167 T 23-10-2018 IPR022429 Alanine-tRNA ligase, archaea GO:0000166|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 A0127_07315 42c9208d0a511c38da587f16d035aaaa 914 SMART SM00863 703 746 2.7E-18 T 23-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 A0127_07315 42c9208d0a511c38da587f16d035aaaa 914 Pfam PF01411 tRNA synthetases class II (A) 61 604 4.7E-163 T 23-10-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 A0127_07315 42c9208d0a511c38da587f16d035aaaa 914 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 61 894 2.5E-236 T 23-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 A0127_07315 42c9208d0a511c38da587f16d035aaaa 914 Gene3D G3DSA:3.30.980.10 606 675 1.0E-21 T 23-10-2018 A0127_07315 42c9208d0a511c38da587f16d035aaaa 914 SUPERFAMILY SSF55681 57 264 3.48E-57 T 23-10-2018 A0127_07315 42c9208d0a511c38da587f16d035aaaa 914 SUPERFAMILY SSF101353 305 515 4.45E-50 T 23-10-2018 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain superfamily GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 A0127_07315 42c9208d0a511c38da587f16d035aaaa 914 Gene3D G3DSA:3.10.310.40 814 914 3.6E-20 T 23-10-2018 A0127_07315 42c9208d0a511c38da587f16d035aaaa 914 Gene3D G3DSA:3.30.54.20 676 727 1.4E-29 T 23-10-2018 A0127_07315 42c9208d0a511c38da587f16d035aaaa 914 SUPERFAMILY SSF50447 513 598 7.77E-20 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily A0127_07315 42c9208d0a511c38da587f16d035aaaa 914 PRINTS PR00980 Alanyl-tRNA synthetase signature 245 258 3.4E-21 T 23-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 A0127_07315 42c9208d0a511c38da587f16d035aaaa 914 PRINTS PR00980 Alanyl-tRNA synthetase signature 206 217 3.4E-21 T 23-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 A0127_07315 42c9208d0a511c38da587f16d035aaaa 914 PRINTS PR00980 Alanyl-tRNA synthetase signature 336 352 3.4E-21 T 23-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 A0127_07315 42c9208d0a511c38da587f16d035aaaa 914 PRINTS PR00980 Alanyl-tRNA synthetase signature 127 138 3.4E-21 T 23-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 A0127_07315 42c9208d0a511c38da587f16d035aaaa 914 PRINTS PR00980 Alanyl-tRNA synthetase signature 360 373 3.4E-21 T 23-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 A0127_07315 42c9208d0a511c38da587f16d035aaaa 914 Gene3D G3DSA:2.40.30.130 503 600 2.6E-38 T 23-10-2018 A0127_07315 42c9208d0a511c38da587f16d035aaaa 914 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 703 745 8.4E-16 T 23-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 A0127_00640 e1ca49d3d91ce1b9c30415acfe74eba8 312 TIGRFAM TIGR01379 thiL: thiamine-phosphate kinase 3 305 2.1E-85 T 23-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 A0127_00640 e1ca49d3d91ce1b9c30415acfe74eba8 312 Hamap MF_02128 Thiamine-monophosphate kinase [thiL]. 1 305 28.756 T 23-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 A0127_00640 e1ca49d3d91ce1b9c30415acfe74eba8 312 SUPERFAMILY SSF55326 16 133 1.38E-30 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A0127_00640 e1ca49d3d91ce1b9c30415acfe74eba8 312 Gene3D G3DSA:3.30.1330.10 1 138 1.4E-34 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A0127_00640 e1ca49d3d91ce1b9c30415acfe74eba8 312 PIRSF PIRSF005303 1 305 4.2E-92 T 23-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 A0127_00640 e1ca49d3d91ce1b9c30415acfe74eba8 312 SUPERFAMILY SSF56042 137 293 3.49E-38 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A0127_00640 e1ca49d3d91ce1b9c30415acfe74eba8 312 Gene3D G3DSA:3.90.650.10 139 305 2.4E-49 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A0127_00640 e1ca49d3d91ce1b9c30415acfe74eba8 312 Pfam PF00586 AIR synthase related protein, N-terminal domain 24 133 5.6E-17 T 23-10-2018 IPR016188 PurM-like, N-terminal domain A0127_00640 e1ca49d3d91ce1b9c30415acfe74eba8 312 Pfam PF02769 AIR synthase related protein, C-terminal domain 144 292 1.1E-7 T 23-10-2018 IPR010918 PurM-like, C-terminal domain A0127_07480 32b09c29047df0481897f9eb3baac353 86 Pfam PF00276 Ribosomal protein L23 5 72 5.7E-20 T 23-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 A0127_07480 32b09c29047df0481897f9eb3baac353 86 Hamap MF_01369_A 50S ribosomal protein L23 [rplW]. 6 86 27.87 T 23-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 A0127_07480 32b09c29047df0481897f9eb3baac353 86 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 4 82 14.805 T 23-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 A0127_07480 32b09c29047df0481897f9eb3baac353 86 Gene3D G3DSA:3.30.70.330 1 86 8.2E-38 T 23-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily A0127_07480 32b09c29047df0481897f9eb3baac353 86 ProSitePatterns PS00050 Ribosomal protein L23 signature. 64 79 - T 23-10-2018 IPR001014 Ribosomal protein L23/L25, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_07480 32b09c29047df0481897f9eb3baac353 86 SUPERFAMILY SSF54189 1 80 3.31E-28 T 23-10-2018 IPR012678 Ribosomal protein L23/L15e core domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 A0127_07480 32b09c29047df0481897f9eb3baac353 86 TIGRFAM TIGR03636 uL23_arch: ribosomal protein uL23 10 86 2.1E-39 T 23-10-2018 IPR019985 Ribosomal protein L23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_01315 e39dec5dc869041b00ba1bb5eefb5f88 632 SUPERFAMILY SSF82171 24 369 1.44E-31 T 23-10-2018 A0127_01315 e39dec5dc869041b00ba1bb5eefb5f88 632 Gene3D G3DSA:2.120.10.30 23 142 3.3E-14 T 23-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like A0127_01315 e39dec5dc869041b00ba1bb5eefb5f88 632 Pfam PF00326 Prolyl oligopeptidase family 421 631 1.8E-59 T 23-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 A0127_01315 e39dec5dc869041b00ba1bb5eefb5f88 632 SUPERFAMILY SSF53474 374 631 5.31E-71 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold A0127_01315 e39dec5dc869041b00ba1bb5eefb5f88 632 Gene3D G3DSA:2.120.10.30 149 290 1.8E-7 T 23-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like A0127_01315 e39dec5dc869041b00ba1bb5eefb5f88 632 Gene3D G3DSA:3.40.50.1820 377 632 4.1E-74 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold A0127_01315 e39dec5dc869041b00ba1bb5eefb5f88 632 Pfam PF07676 WD40-like Beta Propeller Repeat 54 83 5.0E-6 T 23-10-2018 IPR011659 WD40-like Beta Propeller A0127_06855 6ad3c70408d15943bdbdc29e47924c46 390 Gene3D G3DSA:3.90.1170.20 1 106 1.4E-45 T 23-10-2018 IPR037128 Quinolinate phosphoribosyl transferase, N-terminal domain superfamily GO:0016763 Reactome: R-HSA-196807 A0127_06855 6ad3c70408d15943bdbdc29e47924c46 390 SUPERFAMILY SSF54675 2 115 9.55E-33 T 23-10-2018 A0127_06855 6ad3c70408d15943bdbdc29e47924c46 390 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 115 303 1.3E-27 T 23-10-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 Reactome: R-HSA-196807 A0127_06855 6ad3c70408d15943bdbdc29e47924c46 390 Gene3D G3DSA:3.20.20.70 107 297 1.1E-64 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A0127_06855 6ad3c70408d15943bdbdc29e47924c46 390 SUPERFAMILY SSF51690 112 386 1.28E-76 T 23-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 A0127_06855 6ad3c70408d15943bdbdc29e47924c46 390 Gene3D G3DSA:3.20.140.10 299 388 4.8E-6 T 23-10-2018 A0127_06855 6ad3c70408d15943bdbdc29e47924c46 390 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 53 113 1.0E-5 T 23-10-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 A0127_06855 6ad3c70408d15943bdbdc29e47924c46 390 PIRSF PIRSF000484 60 388 4.8E-49 T 23-10-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 A0127_06855 6ad3c70408d15943bdbdc29e47924c46 390 PIRSF PIRSF000484 9 72 14.0 T 23-10-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 A0127_03155 aa24e1e42a8f996021083d2c7a372d07 347 Gene3D G3DSA:3.60.70.12 1 346 3.5E-136 T 23-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 A0127_03155 aa24e1e42a8f996021083d2c7a372d07 347 SUPERFAMILY SSF56266 2 344 5.49E-102 T 23-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 A0127_03155 aa24e1e42a8f996021083d2c7a372d07 347 Pfam PF03576 Peptidase family S58 19 324 2.9E-109 T 23-10-2018 IPR005321 Peptidase S58, DmpA A0127_03795 851715f23c1a2b59e2e5b9b96d81e780 185 Pfam PF01926 50S ribosome-binding GTPase 3 136 5.6E-23 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A0127_03795 851715f23c1a2b59e2e5b9b96d81e780 185 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 4 24 4.8E-8 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A0127_03795 851715f23c1a2b59e2e5b9b96d81e780 185 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 88 106 4.8E-8 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A0127_03795 851715f23c1a2b59e2e5b9b96d81e780 185 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 2 175 2.0E-20 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A0127_03795 851715f23c1a2b59e2e5b9b96d81e780 185 Gene3D G3DSA:3.40.50.300 1 182 2.0E-38 T 23-10-2018 A0127_03795 851715f23c1a2b59e2e5b9b96d81e780 185 SUPERFAMILY SSF52540 2 182 3.62E-36 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_08385 743287ac0de5835346ed87f2d894d7d8 338 Gene3D G3DSA:3.90.650.10 156 338 4.9E-57 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A0127_08385 743287ac0de5835346ed87f2d894d7d8 338 TIGRFAM TIGR02124 hypE: hydrogenase expression/formation protein HypE 4 338 1.2E-119 T 23-10-2018 IPR011854 Carbamoyl dehydratase HypE A0127_08385 743287ac0de5835346ed87f2d894d7d8 338 SUPERFAMILY SSF55326 6 154 8.02E-33 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A0127_08385 743287ac0de5835346ed87f2d894d7d8 338 Pfam PF02769 AIR synthase related protein, C-terminal domain 162 314 7.9E-33 T 23-10-2018 IPR010918 PurM-like, C-terminal domain A0127_08385 743287ac0de5835346ed87f2d894d7d8 338 Pfam PF00586 AIR synthase related protein, N-terminal domain 42 151 1.2E-16 T 23-10-2018 IPR016188 PurM-like, N-terminal domain A0127_08385 743287ac0de5835346ed87f2d894d7d8 338 PIRSF PIRSF005644 1 338 4.3E-124 T 23-10-2018 IPR011854 Carbamoyl dehydratase HypE A0127_08385 743287ac0de5835346ed87f2d894d7d8 338 SUPERFAMILY SSF56042 157 332 5.23E-48 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A0127_08385 743287ac0de5835346ed87f2d894d7d8 338 Gene3D G3DSA:3.30.1330.10 1 155 9.5E-45 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A0127_06850 5f8f4fa5e81ff4cb880932d5a8706e30 299 Pfam PF12706 Beta-lactamase superfamily domain 26 206 5.0E-8 T 23-10-2018 IPR001279 Metallo-beta-lactamase A0127_06850 5f8f4fa5e81ff4cb880932d5a8706e30 299 Hamap MF_01406 UPF0282 protein . 1 286 38.898 T 23-10-2018 IPR014426 Uncharacterised protein family UPF0282, hydrolase, metallo-beta-lactamase A0127_06850 5f8f4fa5e81ff4cb880932d5a8706e30 299 SUPERFAMILY SSF56281 1 262 2.75E-19 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A0127_06850 5f8f4fa5e81ff4cb880932d5a8706e30 299 PIRSF PIRSF004944 1 299 5.5E-118 T 23-10-2018 IPR014426 Uncharacterised protein family UPF0282, hydrolase, metallo-beta-lactamase A0127_06850 5f8f4fa5e81ff4cb880932d5a8706e30 299 Gene3D G3DSA:3.60.15.10 7 273 5.5E-17 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A0127_06335 930cd2dd9c942e4f316b27794709ed97 372 SMART SM00382 28 217 2.0E-13 T 23-10-2018 IPR003593 AAA+ ATPase domain A0127_06335 930cd2dd9c942e4f316b27794709ed97 372 Gene3D G3DSA:2.40.50.140 310 354 2.0E-23 T 23-10-2018 A0127_06335 930cd2dd9c942e4f316b27794709ed97 372 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A0127_06335 930cd2dd9c942e4f316b27794709ed97 372 Pfam PF08402 TOBE domain 288 363 1.3E-5 T 23-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 A0127_06335 930cd2dd9c942e4f316b27794709ed97 372 Gene3D G3DSA:2.40.50.100 245 304 4.6E-25 T 23-10-2018 A0127_06335 930cd2dd9c942e4f316b27794709ed97 372 Pfam PF00005 ABC transporter 20 167 1.8E-31 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A0127_06335 930cd2dd9c942e4f316b27794709ed97 372 SUPERFAMILY SSF50331 242 370 6.32E-25 T 23-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal A0127_06335 930cd2dd9c942e4f316b27794709ed97 372 Gene3D G3DSA:3.40.50.300 1 243 6.2E-77 T 23-10-2018 A0127_06335 930cd2dd9c942e4f316b27794709ed97 372 SUPERFAMILY SSF52540 4 249 2.1E-89 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_07895 cd58603cd0d88565dede704c44054ced 356 SUPERFAMILY SSF53092 2 129 1.6E-12 T 23-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal A0127_07895 cd58603cd0d88565dede704c44054ced 356 SUPERFAMILY SSF55920 130 356 4.19E-78 T 23-10-2018 IPR036005 Creatinase/aminopeptidase-like A0127_07895 cd58603cd0d88565dede704c44054ced 356 Gene3D G3DSA:3.90.230.10 131 356 7.9E-85 T 23-10-2018 A0127_07895 cd58603cd0d88565dede704c44054ced 356 Pfam PF01321 Creatinase/Prolidase N-terminal domain 2 107 2.9E-15 T 23-10-2018 IPR000587 Creatinase, N-terminal GO:0016787 A0127_07895 cd58603cd0d88565dede704c44054ced 356 Gene3D G3DSA:3.40.350.10 1 129 2.3E-28 T 23-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal A0127_07895 cd58603cd0d88565dede704c44054ced 356 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 286 298 - T 23-10-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site A0127_07895 cd58603cd0d88565dede704c44054ced 356 Pfam PF00557 Metallopeptidase family M24 139 338 1.1E-69 T 23-10-2018 IPR000994 Peptidase M24 A0127_04405 161d879203670019ef10ba1684bb7fee 449 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 368 440 1.4E-7 T 23-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A0127_04405 161d879203670019ef10ba1684bb7fee 449 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 90 99 - T 23-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A0127_04405 161d879203670019ef10ba1684bb7fee 449 Gene3D G3DSA:3.40.120.10 247 330 4.9E-55 T 23-10-2018 A0127_04405 161d879203670019ef10ba1684bb7fee 449 Gene3D G3DSA:3.40.120.10 163 345 4.9E-55 T 23-10-2018 A0127_04405 161d879203670019ef10ba1684bb7fee 449 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 151 246 4.0E-18 T 23-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A0127_04405 161d879203670019ef10ba1684bb7fee 449 SUPERFAMILY SSF53738 150 249 2.24E-22 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A0127_04405 161d879203670019ef10ba1684bb7fee 449 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 89 103 2.0E-15 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A0127_04405 161d879203670019ef10ba1684bb7fee 449 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 226 241 2.0E-15 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A0127_04405 161d879203670019ef10ba1684bb7fee 449 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 165 184 2.0E-15 T 23-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A0127_04405 161d879203670019ef10ba1684bb7fee 449 Gene3D G3DSA:3.40.120.10 1 147 1.4E-50 T 23-10-2018 A0127_04405 161d879203670019ef10ba1684bb7fee 449 SUPERFAMILY SSF53738 3 171 3.83E-46 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A0127_04405 161d879203670019ef10ba1684bb7fee 449 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 254 357 1.4E-20 T 23-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A0127_04405 161d879203670019ef10ba1684bb7fee 449 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 3 132 6.3E-44 T 23-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A0127_04405 161d879203670019ef10ba1684bb7fee 449 Hamap MF_01554_A Phosphoglucosamine mutase [glmM]. 2 446 52.096 T 23-10-2018 IPR023666 Phosphoglucosamine mutase, archaeal GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A0127_04405 161d879203670019ef10ba1684bb7fee 449 TIGRFAM TIGR03990 Arch_GlmM: phosphoglucosamine mutase 3 441 3.8E-163 T 23-10-2018 IPR024086 Phosphoglucosamine mutase, archaeal type GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A0127_04405 161d879203670019ef10ba1684bb7fee 449 Gene3D G3DSA:3.30.310.50 360 448 9.3E-22 T 23-10-2018 A0127_04405 161d879203670019ef10ba1684bb7fee 449 SUPERFAMILY SSF55957 348 447 3.4E-23 T 23-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A0127_04405 161d879203670019ef10ba1684bb7fee 449 SUPERFAMILY SSF53738 252 355 5.0E-24 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A0127_10070 ddd944c661a763a56291d44b39cc225d 59 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 12 34 0.0017 T 23-10-2018 A0127_05930 aa010bcf6232b98307d275002b6a9d03 302 Gene3D G3DSA:1.20.81.30 88 207 1.6E-8 T 23-10-2018 A0127_05930 aa010bcf6232b98307d275002b6a9d03 302 Pfam PF00482 Type II secretion system (T2SS), protein F 102 226 9.7E-18 T 23-10-2018 IPR018076 Type II secretion system F domain A0127_08320 dd90d9c70cf8671d4eabfcebe1ab5b1c 820 SUPERFAMILY SSF81853 645 809 1.12E-15 T 23-10-2018 A0127_08320 dd90d9c70cf8671d4eabfcebe1ab5b1c 820 Gene3D G3DSA:3.40.50.12610 377 489 1.1E-6 T 23-10-2018 A0127_08320 dd90d9c70cf8671d4eabfcebe1ab5b1c 820 SUPERFAMILY SSF48208 527 600 9.18E-5 T 23-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 A0127_08320 dd90d9c70cf8671d4eabfcebe1ab5b1c 820 Gene3D G3DSA:1.50.10.20 536 798 2.1E-9 T 23-10-2018 A0127_08320 dd90d9c70cf8671d4eabfcebe1ab5b1c 820 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 67 217 3.7E-13 T 23-10-2018 IPR038731 Glycosyltransferase RgtA/B/C/D-like A0127_06475 9bc89b0c94d64eab2b84f638c5504ff8 427 Pfam PF01882 Protein of unknown function DUF58 181 259 2.3E-16 T 23-10-2018 IPR002881 Domain of unknown function DUF58 A0127_09665 0a38b3e9212c9a86c6d82fa97de6d689 314 SUPERFAMILY SSF56281 3 298 5.13E-76 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A0127_09665 0a38b3e9212c9a86c6d82fa97de6d689 314 Pfam PF12706 Beta-lactamase superfamily domain 32 152 2.5E-10 T 23-10-2018 IPR001279 Metallo-beta-lactamase A0127_09665 0a38b3e9212c9a86c6d82fa97de6d689 314 Pfam PF12706 Beta-lactamase superfamily domain 197 263 2.0E-7 T 23-10-2018 IPR001279 Metallo-beta-lactamase A0127_09665 0a38b3e9212c9a86c6d82fa97de6d689 314 Hamap MF_01818 Ribonuclease BN [rbn]. 2 299 34.546 T 23-10-2018 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 A0127_09665 0a38b3e9212c9a86c6d82fa97de6d689 314 SMART SM00849 19 235 3.2E-6 T 23-10-2018 IPR001279 Metallo-beta-lactamase A0127_09665 0a38b3e9212c9a86c6d82fa97de6d689 314 TIGRFAM TIGR02651 RNase_Z: ribonuclease Z 3 295 4.0E-99 T 23-10-2018 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 A0127_09665 0a38b3e9212c9a86c6d82fa97de6d689 314 Gene3D G3DSA:3.60.15.10 1 299 1.7E-84 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A0127_10050 e1e4d6f6f85abc2f0afcc8f5efd9e9ee 132 SMART SM00232 2 129 6.6E-12 T 23-10-2018 IPR000555 JAB1/MPN/MOV34 metalloenzyme domain GO:0005515 A0127_10050 e1e4d6f6f85abc2f0afcc8f5efd9e9ee 132 Pfam PF14464 Prokaryotic homologs of the JAB domain 17 119 4.5E-17 T 23-10-2018 IPR028090 JAB domain, prokaryotic A0127_10050 e1e4d6f6f85abc2f0afcc8f5efd9e9ee 132 Gene3D G3DSA:3.40.140.10 3 132 2.0E-29 T 23-10-2018 A0127_10050 e1e4d6f6f85abc2f0afcc8f5efd9e9ee 132 SUPERFAMILY SSF102712 2 125 3.01E-22 T 23-10-2018 A0127_00115 d11411a133b18f5be828a2bac5d26350 339 SUPERFAMILY SSF52540 1 335 3.61E-108 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_00115 d11411a133b18f5be828a2bac5d26350 339 SMART SM00788 3 334 1.6E-157 T 23-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 A0127_00115 d11411a133b18f5be828a2bac5d26350 339 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 10 17 - T 23-10-2018 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 A0127_00115 d11411a133b18f5be828a2bac5d26350 339 Pfam PF00709 Adenylosuccinate synthetase 5 149 3.9E-37 T 23-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 A0127_00115 d11411a133b18f5be828a2bac5d26350 339 Pfam PF00709 Adenylosuccinate synthetase 150 289 1.5E-44 T 23-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 A0127_00115 d11411a133b18f5be828a2bac5d26350 339 Pfam PF00709 Adenylosuccinate synthetase 294 333 1.4E-5 T 23-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 A0127_00115 d11411a133b18f5be828a2bac5d26350 339 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 339 97.562 T 23-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 A0127_00115 d11411a133b18f5be828a2bac5d26350 339 Gene3D G3DSA:3.40.440.10 1 339 3.2E-137 T 23-10-2018 A0127_09650 77ad84a7835b02469aba8ac10fef29e9 76 Gene3D G3DSA:3.10.20.30 1 76 2.1E-15 T 23-10-2018 IPR012675 Beta-grasp domain superfamily A0127_09650 77ad84a7835b02469aba8ac10fef29e9 76 SUPERFAMILY SSF54285 1 76 7.29E-12 T 23-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp A0127_09650 77ad84a7835b02469aba8ac10fef29e9 76 Pfam PF02597 ThiS family 4 76 1.5E-9 T 23-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 A0127_00420 eba086177be35d79db4e39b0af69b150 191 SUPERFAMILY SSF109755 3 97 1.44E-16 T 23-10-2018 A0127_00420 eba086177be35d79db4e39b0af69b150 191 SUPERFAMILY SSF116726 103 175 9.94E-19 T 23-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 A0127_00420 eba086177be35d79db4e39b0af69b150 191 Gene3D G3DSA:1.20.58.220 1 110 2.1E-20 T 23-10-2018 IPR038078 PhoU-like domain superfamily A0127_00420 eba086177be35d79db4e39b0af69b150 191 Pfam PF01895 PhoU domain 11 95 8.6E-10 T 23-10-2018 IPR026022 PhoU domain A0127_00420 eba086177be35d79db4e39b0af69b150 191 Pfam PF02080 TrkA-C domain 118 176 5.9E-16 T 23-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A0127_00420 eba086177be35d79db4e39b0af69b150 191 Gene3D G3DSA:3.30.70.1450 111 190 1.5E-20 T 23-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 A0127_07335 55c4a7c555e8e58d285e778b98ff9d51 436 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 2 432 31.356 T 23-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 A0127_07335 55c4a7c555e8e58d285e778b98ff9d51 436 TIGRFAM TIGR00443 hisZ_biosyn_reg: ATP phosphoribosyltransferase, regulatory subunit 11 327 1.3E-87 T 23-10-2018 IPR004517 ATP phosphoribosyltransferase regulatory subunit GO:0000105|GO:0005737 A0127_07335 55c4a7c555e8e58d285e778b98ff9d51 436 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 6 422 2.1E-128 T 23-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 A0127_07335 55c4a7c555e8e58d285e778b98ff9d51 436 Gene3D G3DSA:3.40.50.800 338 433 1.6E-24 T 23-10-2018 IPR036621 Anticodon-binding domain superfamily A0127_07335 55c4a7c555e8e58d285e778b98ff9d51 436 SUPERFAMILY SSF52954 330 434 1.51E-21 T 23-10-2018 A0127_07335 55c4a7c555e8e58d285e778b98ff9d51 436 Gene3D G3DSA:3.30.930.10 1 328 1.4E-111 T 23-10-2018 A0127_07335 55c4a7c555e8e58d285e778b98ff9d51 436 Pfam PF13393 Histidyl-tRNA synthetase 9 323 3.3E-66 T 23-10-2018 A0127_07335 55c4a7c555e8e58d285e778b98ff9d51 436 SUPERFAMILY SSF55681 7 328 1.95E-87 T 23-10-2018 A0127_07335 55c4a7c555e8e58d285e778b98ff9d51 436 Hamap MF_00125 ATP phosphoribosyltransferase regulatory subunit [hisZ]. 16 383 26.175 T 23-10-2018 IPR004517 ATP phosphoribosyltransferase regulatory subunit GO:0000105|GO:0005737 A0127_07335 55c4a7c555e8e58d285e778b98ff9d51 436 Pfam PF03129 Anticodon binding domain 341 432 1.3E-18 T 23-10-2018 IPR004154 Anticodon-binding A0127_07335 55c4a7c555e8e58d285e778b98ff9d51 436 PIRSF PIRSF001549 1 434 1.4E-139 T 23-10-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 A0127_06420 7556568b242de86635226d0c6a1c4149 456 TIGRFAM TIGR03671 cca_archaeal: CCA-adding enzyme 6 420 1.7E-143 T 23-10-2018 IPR008229 tRNA nucleotidyltransferase, archaea GO:0001680|GO:0003723|GO:0004810 A0127_06420 7556568b242de86635226d0c6a1c4149 456 PIRSF PIRSF005335 1 456 2.2E-152 T 23-10-2018 IPR008229 tRNA nucleotidyltransferase, archaea GO:0001680|GO:0003723|GO:0004810 A0127_06420 7556568b242de86635226d0c6a1c4149 456 Pfam PF01909 Nucleotidyltransferase domain 35 141 7.0E-13 T 23-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 A0127_06420 7556568b242de86635226d0c6a1c4149 456 SUPERFAMILY SSF81631 153 279 4.45E-37 T 23-10-2018 A0127_06420 7556568b242de86635226d0c6a1c4149 456 SUPERFAMILY SSF81301 1 150 2.25E-36 T 23-10-2018 A0127_06420 7556568b242de86635226d0c6a1c4149 456 SUPERFAMILY SSF55003 265 451 2.98E-41 T 23-10-2018 IPR011068 Nucleotidyltransferase, class I-like, C-terminal GO:0003723|GO:0016779|GO:0031123 A0127_06420 7556568b242de86635226d0c6a1c4149 456 Gene3D G3DSA:3.30.460.10 16 152 1.4E-87 T 23-10-2018 A0127_06420 7556568b242de86635226d0c6a1c4149 456 Gene3D G3DSA:3.30.70.1550 361 400 1.4E-24 T 23-10-2018 A0127_06420 7556568b242de86635226d0c6a1c4149 456 Gene3D G3DSA:1.10.1410.30 9 278 1.4E-87 T 23-10-2018 A0127_06420 7556568b242de86635226d0c6a1c4149 456 Pfam PF09249 tRNA nucleotidyltransferase, second domain 155 278 9.8E-40 T 23-10-2018 IPR015329 tRNA nucleotidyltransferase, substrate binding GO:0004810|GO:0016437 A0127_06420 7556568b242de86635226d0c6a1c4149 456 Gene3D G3DSA:3.30.70.590 290 427 1.4E-24 T 23-10-2018 A0127_06420 7556568b242de86635226d0c6a1c4149 456 Hamap MF_01264 CCA-adding enzyme [cca]. 1 456 163.999 T 23-10-2018 IPR008229 tRNA nucleotidyltransferase, archaea GO:0001680|GO:0003723|GO:0004810 A0127_03815 847c1a08c48dbb35c844a18b98023493 366 SUPERFAMILY SSF53335 173 339 4.44E-21 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A0127_03815 847c1a08c48dbb35c844a18b98023493 366 Pfam PF01170 Putative RNA methylase family UPF0020 175 321 9.2E-11 T 23-10-2018 IPR000241 Putative RNA methylase domain A0127_03815 847c1a08c48dbb35c844a18b98023493 366 Gene3D G3DSA:3.40.50.150 169 344 3.8E-26 T 23-10-2018 A0127_09605 ca18bc3bc7a7a9ef8d1dcd49c693c819 248 Pfam PF01061 ABC-2 type transporter 28 208 2.2E-19 T 23-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 A0127_09605 ca18bc3bc7a7a9ef8d1dcd49c693c819 248 PIRSF PIRSF006648 2 244 2.0E-15 T 23-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A0127_06955 06a22784d17236f58b7b2d3581eb93b7 99 Gene3D G3DSA:1.10.10.10 1 98 1.2E-24 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A0127_06955 06a22784d17236f58b7b2d3581eb93b7 99 Pfam PF03551 Transcriptional regulator PadR-like family 14 83 2.8E-17 T 23-10-2018 IPR005149 Transcription regulator PadR, N-terminal A0127_06955 06a22784d17236f58b7b2d3581eb93b7 99 SUPERFAMILY SSF46785 3 96 2.37E-26 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A0127_04095 222a6cfd77c04c4ba1ac481cfd979f10 440 Pfam PF00535 Glycosyl transferase family 2 221 342 6.8E-25 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A0127_04095 222a6cfd77c04c4ba1ac481cfd979f10 440 Gene3D G3DSA:3.40.50.1000 6 185 4.9E-31 T 23-10-2018 IPR023214 HAD superfamily A0127_04095 222a6cfd77c04c4ba1ac481cfd979f10 440 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 94 107 6.5E-6 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A0127_04095 222a6cfd77c04c4ba1ac481cfd979f10 440 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 3 14 6.5E-6 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A0127_04095 222a6cfd77c04c4ba1ac481cfd979f10 440 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 145 165 6.5E-6 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A0127_04095 222a6cfd77c04c4ba1ac481cfd979f10 440 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 180 3.3E-24 T 23-10-2018 A0127_04095 222a6cfd77c04c4ba1ac481cfd979f10 440 Gene3D G3DSA:3.90.550.10 215 435 1.3E-46 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A0127_04095 222a6cfd77c04c4ba1ac481cfd979f10 440 SUPERFAMILY SSF56784 2 214 6.04E-37 T 23-10-2018 IPR036412 HAD-like superfamily A0127_04095 222a6cfd77c04c4ba1ac481cfd979f10 440 SUPERFAMILY SSF53448 221 428 1.39E-32 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A0127_04095 222a6cfd77c04c4ba1ac481cfd979f10 440 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 92 177 1.7E-6 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A0127_04095 222a6cfd77c04c4ba1ac481cfd979f10 440 Gene3D G3DSA:1.10.150.240 18 80 4.9E-31 T 23-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 A0127_01535 bf6a16a06f05d6395a2fd1f223c43c7b 257 Gene3D G3DSA:3.40.50.1220 12 242 2.6E-95 T 23-10-2018 A0127_01535 bf6a16a06f05d6395a2fd1f223c43c7b 257 Pfam PF02146 Sir2 family 20 198 7.8E-61 T 23-10-2018 IPR003000 Sirtuin family GO:0070403 A0127_01535 bf6a16a06f05d6395a2fd1f223c43c7b 257 Gene3D G3DSA:3.30.1600.10 29 168 2.6E-95 T 23-10-2018 IPR026591 Sirtuin, catalytic core small domain superfamily A0127_01535 bf6a16a06f05d6395a2fd1f223c43c7b 257 SUPERFAMILY SSF52467 3 253 4.55E-94 T 23-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily A0127_01535 bf6a16a06f05d6395a2fd1f223c43c7b 257 Hamap MF_01121 NAD-dependent protein deacylase [cobB]. 13 248 62.878 T 23-10-2018 IPR027546 Sirtuin, class III GO:0036054|GO:0036055|GO:0070403 Reactome: R-HSA-2151201 A0127_04250 54f9037fb4d6c6fef34e7bb459f71f40 340 Pfam PF05763 Protein of unknown function (DUF835) 138 266 3.0E-38 T 23-10-2018 IPR008553 Domain of unknown function DUF835 A0127_04225 902f784bb0437c875961d8d41b5300a6 211 SMART SM00849 7 175 2.0E-18 T 23-10-2018 IPR001279 Metallo-beta-lactamase A0127_04225 902f784bb0437c875961d8d41b5300a6 211 Gene3D G3DSA:3.60.15.10 1 201 5.2E-48 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A0127_04225 902f784bb0437c875961d8d41b5300a6 211 Pfam PF13483 Beta-lactamase superfamily domain 5 175 5.9E-28 T 23-10-2018 A0127_04225 902f784bb0437c875961d8d41b5300a6 211 SUPERFAMILY SSF56281 1 198 1.48E-35 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A0127_05865 439c3438a6b5d4c1880d5b7bdb90950a 62 Gene3D G3DSA:4.10.1150.10 1 62 4.9E-8 T 23-10-2018 IPR024069 AF2212-like domain superfamily A0127_05865 439c3438a6b5d4c1880d5b7bdb90950a 62 Pfam PF01954 Protein of unknown function DUF104 2 56 8.1E-16 T 23-10-2018 IPR008203 Uncharacterised protein family UPF0165 A0127_05865 439c3438a6b5d4c1880d5b7bdb90950a 62 SUPERFAMILY SSF141694 1 58 1.12E-12 T 23-10-2018 A0127_08415 e9e44ee0d56489a3b3030b1f973773d5 174 Pfam PF00334 Nucleoside diphosphate kinase 7 143 6.3E-57 T 23-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A0127_08415 e9e44ee0d56489a3b3030b1f973773d5 174 ProSitePatterns PS00469 Nucleoside diphosphate kinases active site. 120 128 - T 23-10-2018 IPR023005 Nucleoside diphosphate kinase, active site KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 A0127_08415 e9e44ee0d56489a3b3030b1f973773d5 174 SMART SM00562 6 146 4.2E-83 T 23-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A0127_08415 e9e44ee0d56489a3b3030b1f973773d5 174 PRINTS PR01243 Nucleoside diphosphate kinase signature 9 31 1.9E-43 T 23-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A0127_08415 e9e44ee0d56489a3b3030b1f973773d5 174 PRINTS PR01243 Nucleoside diphosphate kinase signature 73 90 1.9E-43 T 23-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A0127_08415 e9e44ee0d56489a3b3030b1f973773d5 174 PRINTS PR01243 Nucleoside diphosphate kinase signature 53 72 1.9E-43 T 23-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A0127_08415 e9e44ee0d56489a3b3030b1f973773d5 174 PRINTS PR01243 Nucleoside diphosphate kinase signature 94 110 1.9E-43 T 23-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A0127_08415 e9e44ee0d56489a3b3030b1f973773d5 174 PRINTS PR01243 Nucleoside diphosphate kinase signature 120 139 1.9E-43 T 23-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A0127_08415 e9e44ee0d56489a3b3030b1f973773d5 174 Gene3D G3DSA:3.30.70.141 1 159 3.5E-69 T 23-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A0127_08415 e9e44ee0d56489a3b3030b1f973773d5 174 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 6 144 36.221 T 23-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A0127_08415 e9e44ee0d56489a3b3030b1f973773d5 174 SUPERFAMILY SSF54919 6 152 2.75E-60 T 23-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 A0127_06800 2eaebf87a7d01bb63852b259c7e2b0fb 584 SUPERFAMILY SSF48239 336 484 4.71E-11 T 23-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid A0127_06800 2eaebf87a7d01bb63852b259c7e2b0fb 584 SUPERFAMILY SSF48239 26 235 1.82E-17 T 23-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid A0127_06800 2eaebf87a7d01bb63852b259c7e2b0fb 584 Gene3D G3DSA:1.50.10.20 28 171 2.2E-13 T 23-10-2018 A0127_06800 2eaebf87a7d01bb63852b259c7e2b0fb 584 Gene3D G3DSA:1.50.10.20 320 485 7.9E-7 T 23-10-2018 A0127_07780 25b1220588b15f60d6cf078054aa72ea 434 Gene3D G3DSA:1.25.40.10 1 220 5.5E-14 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A0127_07780 25b1220588b15f60d6cf078054aa72ea 434 Gene3D G3DSA:1.25.40.10 289 411 2.0E-9 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A0127_06080 c5b22b84df27e21a6b465f7095954f79 396 Gene3D G3DSA:1.20.1530.20 1 393 1.0E-75 T 23-10-2018 IPR038770 Sodium/solute symporter superfamily A0127_06080 c5b22b84df27e21a6b465f7095954f79 396 Pfam PF00999 Sodium/hydrogen exchanger family 9 383 1.7E-55 T 23-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 A0127_04150 fabc279d67700a762c260c417376963a 194 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 11 190 1.2E-34 T 23-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 A0127_04150 fabc279d67700a762c260c417376963a 194 Gene3D G3DSA:3.40.920.10 1 194 3.9E-35 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 A0127_04150 fabc279d67700a762c260c417376963a 194 SUPERFAMILY SSF53323 2 193 2.22E-27 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 A0127_09785 2741279079228c5fe81c2367e2e1a134 395 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 146 161 1.8E-10 T 23-10-2018 A0127_09785 2741279079228c5fe81c2367e2e1a134 395 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 268 283 1.8E-10 T 23-10-2018 A0127_09785 2741279079228c5fe81c2367e2e1a134 395 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 1.8E-10 T 23-10-2018 A0127_09785 2741279079228c5fe81c2367e2e1a134 395 Hamap MF_01287 Digeranylgeranylglycerophospholipid reductase. 3 389 39.327 T 23-10-2018 IPR023590 Digeranylgeranylglycerophospholipid reductase GO:0016628|GO:0045550|GO:0046467|GO:0055114 KEGG: 00564+1.3.7.11|MetaCyc: PWY-6349 A0127_09785 2741279079228c5fe81c2367e2e1a134 395 SUPERFAMILY SSF51905 3 340 2.1E-38 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A0127_09785 2741279079228c5fe81c2367e2e1a134 395 Pfam PF01494 FAD binding domain 5 321 9.5E-15 T 23-10-2018 IPR002938 FAD-binding domain GO:0071949 A0127_09785 2741279079228c5fe81c2367e2e1a134 395 Gene3D G3DSA:3.30.9.10 71 358 8.3E-107 T 23-10-2018 A0127_09785 2741279079228c5fe81c2367e2e1a134 395 TIGRFAM TIGR02032 GG-red-SF: geranylgeranyl reductase family 5 303 1.5E-75 T 23-10-2018 IPR011777 Geranylgeranyl reductase family GO:0016628|GO:0055114 A0127_09785 2741279079228c5fe81c2367e2e1a134 395 Gene3D G3DSA:3.50.50.60 5 340 8.3E-107 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A0127_01540 d4ef6a40181b582b21a349c9abc197d4 394 Pfam PF03222 Tryptophan/tyrosine permease family 66 391 1.8E-25 T 23-10-2018 IPR018227 Amino acid/polyamine transporter 2 GO:0003333 A0127_05740 b344fef3640715aacb4f1166e500beba 338 Pfam PF07885 Ion channel 29 101 2.7E-17 T 23-10-2018 IPR013099 Potassium channel domain A0127_05740 b344fef3640715aacb4f1166e500beba 338 Pfam PF02254 TrkA-N domain 120 241 4.4E-17 T 23-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 A0127_05740 b344fef3640715aacb4f1166e500beba 338 Gene3D G3DSA:1.10.287.70 2 114 1.1E-21 T 23-10-2018 A0127_05740 b344fef3640715aacb4f1166e500beba 338 PRINTS PR01333 Two pore domain K+ channel signature 57 85 2.2E-7 T 23-10-2018 IPR003280 Two pore domain potassium channel GO:0005267|GO:0016020|GO:0071805 Reactome: R-HSA-5576886 A0127_05740 b344fef3640715aacb4f1166e500beba 338 PRINTS PR01333 Two pore domain K+ channel signature 121 130 2.2E-7 T 23-10-2018 IPR003280 Two pore domain potassium channel GO:0005267|GO:0016020|GO:0071805 Reactome: R-HSA-5576886 A0127_05740 b344fef3640715aacb4f1166e500beba 338 Gene3D G3DSA:3.40.50.720 117 266 1.7E-25 T 23-10-2018 A0127_05740 b344fef3640715aacb4f1166e500beba 338 SUPERFAMILY SSF81324 14 132 1.11E-26 T 23-10-2018 A0127_05740 b344fef3640715aacb4f1166e500beba 338 SUPERFAMILY SSF51735 116 264 8.86E-21 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A0127_02510 5f1f7fe3a2053991719401aa6cbd0c3e 312 TIGRFAM TIGR00446 nop2p: NOL1/NOP2/sun family putative RNA methylase 39 306 6.1E-92 T 23-10-2018 IPR011023 Nop2p GO:0003723|GO:0006364|GO:0008757 Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 A0127_02510 5f1f7fe3a2053991719401aa6cbd0c3e 312 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 228 244 5.7E-23 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A0127_02510 5f1f7fe3a2053991719401aa6cbd0c3e 312 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 112 122 5.7E-23 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A0127_02510 5f1f7fe3a2053991719401aa6cbd0c3e 312 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 83 97 5.7E-23 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A0127_02510 5f1f7fe3a2053991719401aa6cbd0c3e 312 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 178 190 5.7E-23 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A0127_02510 5f1f7fe3a2053991719401aa6cbd0c3e 312 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 289 306 5.7E-23 T 23-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase A0127_02510 5f1f7fe3a2053991719401aa6cbd0c3e 312 SUPERFAMILY SSF53335 22 306 7.21E-61 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A0127_02510 5f1f7fe3a2053991719401aa6cbd0c3e 312 Pfam PF17125 N-terminal domain of 16S rRNA methyltransferase RsmF 13 97 1.9E-16 T 23-10-2018 IPR031341 Ribosomal RNA small subunit methyltransferase F, N-terminal Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 A0127_02510 5f1f7fe3a2053991719401aa6cbd0c3e 312 Gene3D G3DSA:3.40.50.150 101 311 1.7E-72 T 23-10-2018 A0127_02510 5f1f7fe3a2053991719401aa6cbd0c3e 312 Gene3D G3DSA:3.30.70.3130 5 96 1.1E-16 T 23-10-2018 A0127_02510 5f1f7fe3a2053991719401aa6cbd0c3e 312 Pfam PF01189 16S rRNA methyltransferase RsmB/F 101 304 2.3E-52 T 23-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 A0127_05190 4d67ba10f099d17c85b63460f8bae316 622 SUPERFAMILY SSF82171 24 340 3.92E-25 T 23-10-2018 A0127_05190 4d67ba10f099d17c85b63460f8bae316 622 SUPERFAMILY SSF53474 338 612 4.61E-58 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold A0127_05190 4d67ba10f099d17c85b63460f8bae316 622 Gene3D G3DSA:2.120.10.30 21 197 1.7E-12 T 23-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like A0127_05190 4d67ba10f099d17c85b63460f8bae316 622 Pfam PF00326 Prolyl oligopeptidase family 396 607 1.9E-52 T 23-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 A0127_05190 4d67ba10f099d17c85b63460f8bae316 622 Gene3D G3DSA:3.40.50.1820 353 622 1.3E-84 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold A0127_08835 874c4c53a7ad55d6b45f82b4813352aa 299 Pfam PF00146 NADH dehydrogenase 13 298 3.8E-62 T 23-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A0127_10295 3db29fd746674461f2ad13dd515c47f7 125 Gene3D G3DSA:3.30.310.70 5 125 5.3E-10 T 23-10-2018 IPR035923 TT1751-like domain superfamily A0127_10295 3db29fd746674461f2ad13dd515c47f7 125 SUPERFAMILY SSF103247 2 125 1.02E-16 T 23-10-2018 IPR035923 TT1751-like domain superfamily A0127_10295 3db29fd746674461f2ad13dd515c47f7 125 Pfam PF03625 Domain of unknown function DUF302 49 88 1.9E-5 T 23-10-2018 IPR005180 Domain of unknown function DUF302 A0127_01520 1ebe16e344aa665a2fd041efa2c54a03 218 Pfam PF01569 PAP2 superfamily 81 182 3.6E-17 T 23-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase A0127_01520 1ebe16e344aa665a2fd041efa2c54a03 218 SMART SM00014 81 189 5.9E-7 T 23-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase A0127_01520 1ebe16e344aa665a2fd041efa2c54a03 218 SUPERFAMILY SSF48317 29 200 1.09E-26 T 23-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily A0127_01520 1ebe16e344aa665a2fd041efa2c54a03 218 Gene3D G3DSA:1.20.144.10 108 207 6.4E-12 T 23-10-2018 A0127_02845 7f466fe5b1e0ae89b83ab5885d505133 223 Pfam PF00795 Carbon-nitrogen hydrolase 2 157 9.0E-18 T 23-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 A0127_02845 7f466fe5b1e0ae89b83ab5885d505133 223 SUPERFAMILY SSF56317 1 212 8.24E-38 T 23-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily A0127_02845 7f466fe5b1e0ae89b83ab5885d505133 223 Gene3D G3DSA:3.60.110.10 1 220 5.5E-33 T 23-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily A0127_02830 3a23ed139a0e9bd467c2a89b4545993c 187 Pfam PF00881 Nitroreductase family 8 165 4.1E-29 T 23-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 A0127_02830 3a23ed139a0e9bd467c2a89b4545993c 187 SUPERFAMILY SSF55469 1 187 6.02E-48 T 23-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A0127_02830 3a23ed139a0e9bd467c2a89b4545993c 187 Gene3D G3DSA:3.40.109.10 1 185 6.3E-50 T 23-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A0127_07415 3dc10c9193959ce58d38989f7b11771b 276 SUPERFAMILY SSF52402 32 203 1.57E-31 T 23-10-2018 A0127_07415 3dc10c9193959ce58d38989f7b11771b 276 Gene3D G3DSA:3.40.50.620 2 166 4.0E-31 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A0127_07415 3dc10c9193959ce58d38989f7b11771b 276 PIRSF PIRSF036668 1 274 1.1E-126 T 23-10-2018 IPR012121 ATPase, PP-loop, MJ1599-related A0127_07415 3dc10c9193959ce58d38989f7b11771b 276 Pfam PF01171 PP-loop family 55 160 4.6E-8 T 23-10-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 A0127_02935 f650fb9388eab8e53dc8f96a210f9f95 335 Hamap MF_01824 Pyridoxal 5'-phosphate synthase subunit PdxS [pdxS]. 10 335 53.769 T 23-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A0127_02935 f650fb9388eab8e53dc8f96a210f9f95 335 Pfam PF05690 Thiazole biosynthesis protein ThiG 245 299 2.3E-8 T 23-10-2018 IPR033983 Thiazole synthase ThiG KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 A0127_02935 f650fb9388eab8e53dc8f96a210f9f95 335 Pfam PF01680 SOR/SNZ family 13 212 2.1E-95 T 23-10-2018 IPR033755 PdxS/SNZ N-terminal domain KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A0127_02935 f650fb9388eab8e53dc8f96a210f9f95 335 PIRSF PIRSF029271 3 335 6.0E-149 T 23-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A0127_02935 f650fb9388eab8e53dc8f96a210f9f95 335 Gene3D G3DSA:3.20.20.70 1 316 2.6E-153 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A0127_02935 f650fb9388eab8e53dc8f96a210f9f95 335 SUPERFAMILY SSF51366 24 310 7.06E-62 T 23-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 A0127_02935 f650fb9388eab8e53dc8f96a210f9f95 335 ProSitePatterns PS01235 PdxS/SNZ family signature. 248 266 - T 23-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A0127_02935 f650fb9388eab8e53dc8f96a210f9f95 335 TIGRFAM TIGR00343 TIGR00343: pyridoxal 5'-phosphate synthase, synthase subunit Pdx1 15 334 2.4E-146 T 23-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 A0127_08035 31ed9993d9caec0ca6f9ebd744afc22e 373 Gene3D G3DSA:3.30.1330.20 254 362 4.6E-35 T 23-10-2018 IPR037103 Tubulin/FtsZ, C-terminal domain superfamily Reactome: R-HSA-380320 A0127_08035 31ed9993d9caec0ca6f9ebd744afc22e 373 ProSitePatterns PS01134 FtsZ protein signature 1. 74 108 - T 23-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 A0127_08035 31ed9993d9caec0ca6f9ebd744afc22e 373 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 39 373 38.444 T 23-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 A0127_08035 31ed9993d9caec0ca6f9ebd744afc22e 373 SMART SM00864 43 234 1.1E-108 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A0127_08035 31ed9993d9caec0ca6f9ebd744afc22e 373 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 31 355 1.2E-136 T 23-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 A0127_08035 31ed9993d9caec0ca6f9ebd744afc22e 373 SUPERFAMILY SSF52490 38 235 3.53E-70 T 23-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 A0127_08035 31ed9993d9caec0ca6f9ebd744afc22e 373 SUPERFAMILY SSF55307 236 347 4.81E-38 T 23-10-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 A0127_08035 31ed9993d9caec0ca6f9ebd744afc22e 373 ProSitePatterns PS01135 FtsZ protein signature 2. 127 148 - T 23-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 A0127_08035 31ed9993d9caec0ca6f9ebd744afc22e 373 SMART SM00865 236 352 2.7E-49 T 23-10-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-380320 A0127_08035 31ed9993d9caec0ca6f9ebd744afc22e 373 PRINTS PR00423 Cell division protein FtsZ signature 218 240 4.8E-44 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A0127_08035 31ed9993d9caec0ca6f9ebd744afc22e 373 PRINTS PR00423 Cell division protein FtsZ signature 128 148 4.8E-44 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A0127_08035 31ed9993d9caec0ca6f9ebd744afc22e 373 PRINTS PR00423 Cell division protein FtsZ signature 156 177 4.8E-44 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A0127_08035 31ed9993d9caec0ca6f9ebd744afc22e 373 PRINTS PR00423 Cell division protein FtsZ signature 241 262 4.8E-44 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A0127_08035 31ed9993d9caec0ca6f9ebd744afc22e 373 Pfam PF12327 FtsZ family, C-terminal domain 251 343 1.9E-31 T 23-10-2018 IPR024757 Cell division protein FtsZ, C-terminal A0127_08035 31ed9993d9caec0ca6f9ebd744afc22e 373 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 43 203 7.8E-47 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A0127_08035 31ed9993d9caec0ca6f9ebd744afc22e 373 Gene3D G3DSA:3.40.50.1440 35 249 2.0E-83 T 23-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 A0127_05760 3ae2bd109b5c98f453c0133780be3de7 242 TIGRFAM TIGR00161 TIGR00161: TIGR00161 family protein 10 235 1.3E-64 T 23-10-2018 IPR004425 Conserved hypothetical protein CHP00061 A0127_05760 3ae2bd109b5c98f453c0133780be3de7 242 Gene3D G3DSA:3.40.50.10900 1 242 3.6E-74 T 23-10-2018 IPR038389 Proteasome assembly chaperone 2 superfamily A0127_05760 3ae2bd109b5c98f453c0133780be3de7 242 Pfam PF09754 PAC2 family 19 222 4.2E-47 T 23-10-2018 IPR019151 Proteasome assembly chaperone 2 A0127_05760 3ae2bd109b5c98f453c0133780be3de7 242 SUPERFAMILY SSF159659 11 239 2.75E-49 T 23-10-2018 A0127_01040 c22e8f2843e2f4334cee93ef32aab029 1000 Pfam PF02516 Oligosaccharyl transferase STT3 subunit 122 537 3.8E-11 T 23-10-2018 IPR003674 Oligosaccharyl transferase, STT3 subunit GO:0004576|GO:0006486|GO:0016020 A0127_01040 c22e8f2843e2f4334cee93ef32aab029 1000 Gene3D G3DSA:2.40.128.390 620 693 5.8E-43 T 23-10-2018 A0127_01040 c22e8f2843e2f4334cee93ef32aab029 1000 Gene3D G3DSA:2.60.40.3030 858 990 5.2E-111 T 23-10-2018 A0127_01040 c22e8f2843e2f4334cee93ef32aab029 1000 Gene3D G3DSA:3.40.50.12610 510 722 5.8E-43 T 23-10-2018 A0127_01040 c22e8f2843e2f4334cee93ef32aab029 1000 Gene3D G3DSA:2.60.40.3020 748 997 5.2E-111 T 23-10-2018 A0127_03245 29603301a26d45f056988dd9570ad216 246 Gene3D G3DSA:1.10.150.400 14 89 7.4E-26 T 23-10-2018 A0127_03245 29603301a26d45f056988dd9570ad216 246 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 159 179 2.3E-6 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A0127_03245 29603301a26d45f056988dd9570ad216 246 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 107 120 2.3E-6 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A0127_03245 29603301a26d45f056988dd9570ad216 246 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 1 12 2.3E-6 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A0127_03245 29603301a26d45f056988dd9570ad216 246 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 141 157 2.3E-6 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A0127_03245 29603301a26d45f056988dd9570ad216 246 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 135 192 7.9E-6 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A0127_03245 29603301a26d45f056988dd9570ad216 246 Gene3D G3DSA:3.40.50.1000 90 229 7.7E-33 T 23-10-2018 IPR023214 HAD superfamily A0127_03245 29603301a26d45f056988dd9570ad216 246 SUPERFAMILY SSF56784 1 226 1.84E-34 T 23-10-2018 IPR036412 HAD-like superfamily A0127_03245 29603301a26d45f056988dd9570ad216 246 Pfam PF13419 Haloacid dehalogenase-like hydrolase 77 197 1.6E-11 T 23-10-2018 A0127_08225 ad393b802659fb90d0b6e5788c4e2d07 452 Gene3D G3DSA:3.90.1150.10 70 442 3.1E-151 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A0127_08225 ad393b802659fb90d0b6e5788c4e2d07 452 PIRSF PIRSF006815 3 446 6.7E-162 T 23-10-2018 IPR023010 Probable glycine dehydrogenase (decarboxylating) subunit 1 GO:0004375|GO:0009116 KEGG: 00260+1.4.4.2 A0127_08225 ad393b802659fb90d0b6e5788c4e2d07 452 SUPERFAMILY SSF53383 3 444 7.48E-101 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A0127_08225 ad393b802659fb90d0b6e5788c4e2d07 452 Gene3D G3DSA:3.40.640.10 81 349 3.1E-151 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A0127_08225 ad393b802659fb90d0b6e5788c4e2d07 452 Hamap MF_00712 Probable glycine dehydrogenase (decarboxylating) subunit 1 [gcvPA]. 3 445 47.244 T 23-10-2018 IPR023010 Probable glycine dehydrogenase (decarboxylating) subunit 1 GO:0004375|GO:0009116 KEGG: 00260+1.4.4.2 A0127_08225 ad393b802659fb90d0b6e5788c4e2d07 452 Pfam PF02347 Glycine cleavage system P-protein 5 441 7.2E-123 T 23-10-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 A0127_06455 589d26a3c8f9c9ba4e27a54e65771e18 145 Gene3D G3DSA:1.20.1260.10 1 144 4.4E-13 T 23-10-2018 IPR012347 Ferritin-like A0127_06455 589d26a3c8f9c9ba4e27a54e65771e18 145 Pfam PF02915 Rubrerythrin 91 144 1.8E-6 T 23-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 A0127_06455 589d26a3c8f9c9ba4e27a54e65771e18 145 SUPERFAMILY SSF47240 5 143 2.96E-16 T 23-10-2018 IPR009078 Ferritin-like superfamily A0127_05730 627740694fe0759f78e29b27b47faf54 727 SUPERFAMILY SSF50249 367 428 2.94E-5 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A0127_05730 627740694fe0759f78e29b27b47faf54 727 Gene3D G3DSA:3.60.21.50 443 702 1.3E-24 T 23-10-2018 A0127_05730 627740694fe0759f78e29b27b47faf54 727 Pfam PF01336 OB-fold nucleic acid binding domain 372 431 1.4E-6 T 23-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 A0127_05730 627740694fe0759f78e29b27b47faf54 727 Gene3D G3DSA:1.10.8.800 1 65 2.2E-23 T 23-10-2018 A0127_05730 627740694fe0759f78e29b27b47faf54 727 Hamap MF_00325 DNA polymerase II small subunit [polB]. 1 717 32.657 T 23-10-2018 IPR011149 DNA polymerase II small subunit, archaeal GO:0003676|GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A0127_05730 627740694fe0759f78e29b27b47faf54 727 SUPERFAMILY SSF56300 461 688 6.21E-21 T 23-10-2018 A0127_05730 627740694fe0759f78e29b27b47faf54 727 Gene3D G3DSA:2.40.50.140 343 431 1.4E-5 T 23-10-2018 A0127_05730 627740694fe0759f78e29b27b47faf54 727 PIRSF PIRSF000803 8 724 2.0E-176 T 23-10-2018 IPR011149 DNA polymerase II small subunit, archaeal GO:0003676|GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A0127_05730 627740694fe0759f78e29b27b47faf54 727 Pfam PF04042 DNA polymerase alpha/epsilon subunit B 462 665 8.2E-15 T 23-10-2018 IPR007185 DNA polymerase alpha/epsilon, subunit B GO:0003677|GO:0003887|GO:0006260 A0127_10170 a1826c8b59b2934d2fb2512376561fde 245 Gene3D G3DSA:3.60.40.10 4 244 1.2E-61 T 23-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A0127_10170 a1826c8b59b2934d2fb2512376561fde 245 Pfam PF13672 Protein phosphatase 2C 15 208 3.7E-17 T 23-10-2018 A0127_10170 a1826c8b59b2934d2fb2512376561fde 245 SMART SM00332 3 242 3.4E-37 T 23-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A0127_10170 a1826c8b59b2934d2fb2512376561fde 245 SUPERFAMILY SSF81606 13 242 1.11E-56 T 23-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A0127_10170 a1826c8b59b2934d2fb2512376561fde 245 SMART SM00331 11 244 1.6E-26 T 23-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 A0127_02520 d2859185687b0e158d31543673a39b40 960 Gene3D G3DSA:3.90.1860.10 1 122 8.8E-41 T 23-10-2018 IPR036025 tRNA-splicing ligase RtcB-like superfamily GO:0006396|GO:0008452 Reactome: R-HSA-6784531 A0127_02520 d2859185687b0e158d31543673a39b40 960 Gene3D G3DSA:3.90.1860.10 559 960 1.9E-178 T 23-10-2018 IPR036025 tRNA-splicing ligase RtcB-like superfamily GO:0006396|GO:0008452 Reactome: R-HSA-6784531 A0127_02520 d2859185687b0e158d31543673a39b40 960 SUPERFAMILY SSF103365 2 97 1.96E-30 T 23-10-2018 IPR036025 tRNA-splicing ligase RtcB-like superfamily GO:0006396|GO:0008452 Reactome: R-HSA-6784531 A0127_02520 d2859185687b0e158d31543673a39b40 960 PRINTS PR00379 Intein signature 398 413 2.6E-13 T 23-10-2018 IPR006142 Intein GO:0016539 A0127_02520 d2859185687b0e158d31543673a39b40 960 PRINTS PR00379 Intein signature 358 370 2.6E-13 T 23-10-2018 IPR006142 Intein GO:0016539 A0127_02520 d2859185687b0e158d31543673a39b40 960 PRINTS PR00379 Intein signature 572 581 2.6E-13 T 23-10-2018 IPR006142 Intein GO:0016539 A0127_02520 d2859185687b0e158d31543673a39b40 960 PRINTS PR00379 Intein signature 163 176 2.6E-13 T 23-10-2018 IPR006142 Intein GO:0016539 A0127_02520 d2859185687b0e158d31543673a39b40 960 PRINTS PR00379 Intein signature 244 256 2.6E-13 T 23-10-2018 IPR006142 Intein GO:0016539 A0127_02520 d2859185687b0e158d31543673a39b40 960 TIGRFAM TIGR01445 intein_Nterm: intein N-terminal splicing region 97 176 9.3E-10 T 23-10-2018 IPR006141 Intein N-terminal splicing region GO:0016539 Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A0127_02520 d2859185687b0e158d31543673a39b40 960 Pfam PF01139 tRNA-splicing ligase RtcB 45 960 8.2E-180 T 23-10-2018 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 A0127_02520 d2859185687b0e158d31543673a39b40 960 Pfam PF14528 LAGLIDADG-like domain 357 443 3.0E-18 T 23-10-2018 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 A0127_02520 d2859185687b0e158d31543673a39b40 960 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 556 578 7.4E-8 T 23-10-2018 IPR030934 Intein C-terminal splicing region A0127_02520 d2859185687b0e158d31543673a39b40 960 SMART SM00305 535 583 1.8E-11 T 23-10-2018 IPR003586 Hint domain C-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A0127_02520 d2859185687b0e158d31543673a39b40 960 SUPERFAMILY SSF55608 341 452 2.55E-18 T 23-10-2018 IPR027434 Homing endonuclease A0127_02520 d2859185687b0e158d31543673a39b40 960 Gene3D G3DSA:3.10.28.10 243 442 4.1E-25 T 23-10-2018 IPR027434 Homing endonuclease A0127_02520 d2859185687b0e158d31543673a39b40 960 SMART SM00306 95 196 1.1E-19 T 23-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A0127_02520 d2859185687b0e158d31543673a39b40 960 SUPERFAMILY SSF51294 96 577 9.03E-28 T 23-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 A0127_02520 d2859185687b0e158d31543673a39b40 960 SUPERFAMILY SSF103365 577 960 6.15E-147 T 23-10-2018 IPR036025 tRNA-splicing ligase RtcB-like superfamily GO:0006396|GO:0008452 Reactome: R-HSA-6784531 A0127_02520 d2859185687b0e158d31543673a39b40 960 Pfam PF14890 Intein splicing domain 149 577 6.8E-15 T 23-10-2018 A0127_06265 69a0490e7f523bc3590d8b4950e440c6 506 Pfam PF01972 Serine dehydrogenase proteinase 37 105 2.4E-4 T 23-10-2018 IPR002825 Peptidase S49, serine-peptidase prokaryotes GO:0016021 A0127_06265 69a0490e7f523bc3590d8b4950e440c6 506 Pfam PF12161 HsdM N-terminal domain 7 144 2.4E-23 T 23-10-2018 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain A0127_06265 69a0490e7f523bc3590d8b4950e440c6 506 Pfam PF02384 N-6 DNA Methylase 154 470 1.5E-109 T 23-10-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 A0127_06265 69a0490e7f523bc3590d8b4950e440c6 506 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 282 288 - T 23-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 A0127_06265 69a0490e7f523bc3590d8b4950e440c6 506 SUPERFAMILY SSF53335 6 504 1.97E-132 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A0127_06265 69a0490e7f523bc3590d8b4950e440c6 506 Gene3D G3DSA:1.20.1260.30 2 147 2.8E-18 T 23-10-2018 IPR038333 N6 adenine-specific DNA methyltransferase, N-terminal domain superfamily A0127_06265 69a0490e7f523bc3590d8b4950e440c6 506 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 178 194 9.1E-15 T 23-10-2018 A0127_06265 69a0490e7f523bc3590d8b4950e440c6 506 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 202 216 9.1E-15 T 23-10-2018 A0127_06265 69a0490e7f523bc3590d8b4950e440c6 506 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 279 291 9.1E-15 T 23-10-2018 A0127_06265 69a0490e7f523bc3590d8b4950e440c6 506 Gene3D G3DSA:3.40.50.150 155 455 5.1E-100 T 23-10-2018 A0127_01660 5ca26579c8903e13f4e0a667e5511c15 342 Gene3D G3DSA:1.20.120.140 28 128 3.1E-24 T 23-10-2018 A0127_01660 5ca26579c8903e13f4e0a667e5511c15 342 Pfam PF02881 SRP54-type protein, helical bundle domain 61 120 8.0E-13 T 23-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A0127_01660 5ca26579c8903e13f4e0a667e5511c15 342 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 313 326 - T 23-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A0127_01660 5ca26579c8903e13f4e0a667e5511c15 342 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 65 340 59.277 T 23-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 A0127_01660 5ca26579c8903e13f4e0a667e5511c15 342 SMART SM00962 145 340 1.5E-115 T 23-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A0127_01660 5ca26579c8903e13f4e0a667e5511c15 342 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 66 339 3.0E-109 T 23-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 A0127_01660 5ca26579c8903e13f4e0a667e5511c15 342 Gene3D G3DSA:3.40.50.300 131 339 1.3E-86 T 23-10-2018 A0127_01660 5ca26579c8903e13f4e0a667e5511c15 342 Pfam PF00448 SRP54-type protein, GTPase domain 145 339 1.8E-80 T 23-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A0127_01660 5ca26579c8903e13f4e0a667e5511c15 342 SMART SM00382 144 339 7.4E-9 T 23-10-2018 IPR003593 AAA+ ATPase domain A0127_01660 5ca26579c8903e13f4e0a667e5511c15 342 SUPERFAMILY SSF52540 143 340 1.61E-56 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_01660 5ca26579c8903e13f4e0a667e5511c15 342 SUPERFAMILY SSF47364 60 130 2.36E-16 T 23-10-2018 IPR036225 SRP/SRP receptor, N-terminal Reactome: R-HSA-1799339 A0127_01660 5ca26579c8903e13f4e0a667e5511c15 342 SMART SM00963 47 126 7.7E-11 T 23-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 A0127_07660 359b2d12159d43136ea13885e7e6aaaf 140 PIRSF PIRSF002131 1 139 5.3E-37 T 23-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 A0127_07660 359b2d12159d43136ea13885e7e6aaaf 140 TIGRFAM TIGR03628 arch_S11P: ribosomal protein uS11 16 132 1.1E-67 T 23-10-2018 IPR019961 Ribosomal protein S11, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 A0127_07660 359b2d12159d43136ea13885e7e6aaaf 140 Gene3D G3DSA:3.30.420.80 4 140 2.5E-66 T 23-10-2018 IPR036967 Ribosomal protein S11 superfamily GO:0003735|GO:0005840|GO:0006412 A0127_07660 359b2d12159d43136ea13885e7e6aaaf 140 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 12 137 24.005 T 23-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 A0127_07660 359b2d12159d43136ea13885e7e6aaaf 140 SUPERFAMILY SSF53137 12 138 3.79E-40 T 23-10-2018 A0127_07660 359b2d12159d43136ea13885e7e6aaaf 140 Pfam PF00411 Ribosomal protein S11 18 136 3.6E-48 T 23-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 A0127_07660 359b2d12159d43136ea13885e7e6aaaf 140 ProSitePatterns PS00054 Ribosomal protein S11 signature. 105 127 - T 23-10-2018 IPR018102 Ribosomal S11, conserved site A0127_08130 a40588beda084cb5ea4f441d1f2f2aa9 205 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 1 194 7.2E-57 T 23-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 A0127_08130 a40588beda084cb5ea4f441d1f2f2aa9 205 Pfam PF02223 Thymidylate kinase 5 194 1.3E-54 T 23-10-2018 IPR039430 Thymidylate kinase-like domain KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210 A0127_08130 a40588beda084cb5ea4f441d1f2f2aa9 205 Hamap MF_00165 Thymidylate kinase [tmk]. 1 202 28.717 T 23-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 A0127_08130 a40588beda084cb5ea4f441d1f2f2aa9 205 Gene3D G3DSA:3.40.50.300 1 204 3.1E-69 T 23-10-2018 A0127_08130 a40588beda084cb5ea4f441d1f2f2aa9 205 SUPERFAMILY SSF52540 2 202 2.92E-53 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_08130 a40588beda084cb5ea4f441d1f2f2aa9 205 ProSitePatterns PS01331 Thymidylate kinase signature. 96 108 - T 23-10-2018 IPR018095 Thymidylate kinase, conserved site GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 A0127_04825 58dd9a776e5de676b87a6a2e2ea1602b 300 PIRSF PIRSF016896 1 295 1.5E-91 T 23-10-2018 IPR012043 Pantoate kinase KEGG: 00770+2.7.1.169|MetaCyc: PWY-6654 A0127_04825 58dd9a776e5de676b87a6a2e2ea1602b 300 SUPERFAMILY SSF54211 1 157 1.14E-11 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A0127_04825 58dd9a776e5de676b87a6a2e2ea1602b 300 Pfam PF00288 GHMP kinases N terminal domain 93 151 7.1E-5 T 23-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 A0127_07730 bd493e9f611f464819434f441312a10d 99 Pfam PF04930 FUN14 family 12 96 6.1E-13 T 23-10-2018 IPR007014 FUN14 A0127_09515 14d51701c046a99954401be26595100b 243 SUPERFAMILY SSF52540 19 240 8.62E-42 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_09515 14d51701c046a99954401be26595100b 243 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 17 231 8.8E-55 T 23-10-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 A0127_09515 14d51701c046a99954401be26595100b 243 Gene3D G3DSA:3.40.50.300 1 225 1.9E-69 T 23-10-2018 A0127_09515 14d51701c046a99954401be26595100b 243 Hamap MF_02040 Iron-sulfur cluster carrier protein. 13 237 28.452 T 23-10-2018 IPR019591 Mrp/NBP35 ATP-binding protein A0127_07205 dcac729dd56e0320dd4d88fdaf336991 409 Gene3D G3DSA:1.10.287.950 117 409 2.1E-58 T 23-10-2018 A0127_07205 dcac729dd56e0320dd4d88fdaf336991 409 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 165 194 2.8E-21 T 23-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 A0127_07205 dcac729dd56e0320dd4d88fdaf336991 409 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 242 269 2.8E-21 T 23-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 A0127_07205 dcac729dd56e0320dd4d88fdaf336991 409 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 271 300 2.8E-21 T 23-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 A0127_07205 dcac729dd56e0320dd4d88fdaf336991 409 SUPERFAMILY SSF58104 131 404 3.73E-55 T 23-10-2018 A0127_07205 dcac729dd56e0320dd4d88fdaf336991 409 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 219 369 1.3E-34 T 23-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 A0127_07205 dcac729dd56e0320dd4d88fdaf336991 409 SMART SM00283 137 405 8.3E-45 T 23-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 A0127_08815 94d5426504506aec51d4cd55105b28cb 235 Pfam PF04039 Domain related to MnhB subunit of Na+/H+ antiporter 98 221 7.3E-24 T 23-10-2018 IPR007182 Na+/H+ antiporter MnhB subunit-related protein A0127_03650 b5e3a3a68ea66071dcb11e049af85230 232 Pfam PF06745 KaiC 15 225 4.5E-18 T 23-10-2018 IPR014774 KaiC-like domain A0127_03650 b5e3a3a68ea66071dcb11e049af85230 232 Gene3D G3DSA:3.40.50.300 3 232 4.6E-44 T 23-10-2018 A0127_03650 b5e3a3a68ea66071dcb11e049af85230 232 SUPERFAMILY SSF52540 4 221 8.01E-26 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_00225 f53b93a0a12963a77acda53fd6569cab 227 Gene3D G3DSA:3.30.70.2660 21 205 2.8E-8 T 23-10-2018 A0127_00225 f53b93a0a12963a77acda53fd6569cab 227 TIGRFAM TIGR02593 CRISPR_cas5: CRISPR-associated protein Cas5 4 45 3.3E-12 T 23-10-2018 IPR013422 CRISPR-associated protein Cas5, N-terminal A0127_00225 f53b93a0a12963a77acda53fd6569cab 227 Pfam PF09704 CRISPR-associated protein (Cas_Cas5) 25 191 3.8E-11 T 23-10-2018 IPR021124 CRISPR-associated protein, Cas5 GO:0043571 A0127_03680 284740a2975484fb26b1dfa376f4b0e0 218 Pfam PF01917 Archaebacterial flagellin 4 204 2.2E-47 T 23-10-2018 IPR002774 Flagellin, archaea GO:0005198|GO:0006928 A0127_03680 284740a2975484fb26b1dfa376f4b0e0 218 TIGRFAM TIGR02537 arch_flag_Nterm: archaeal flagellin N-terminal-like domain 2 25 1.0E-5 T 23-10-2018 IPR013373 Flagellin/pilin, N-terminal A0127_00830 f4aafa06a0e94ea8c07b59d1f35a498e 278 PRINTS PR00069 Aldo-keto reductase signature 212 236 2.2E-18 T 23-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A0127_00830 f4aafa06a0e94ea8c07b59d1f35a498e 278 PRINTS PR00069 Aldo-keto reductase signature 49 73 2.2E-18 T 23-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A0127_00830 f4aafa06a0e94ea8c07b59d1f35a498e 278 PRINTS PR00069 Aldo-keto reductase signature 105 123 2.2E-18 T 23-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A0127_00830 f4aafa06a0e94ea8c07b59d1f35a498e 278 PRINTS PR00069 Aldo-keto reductase signature 137 154 2.2E-18 T 23-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A0127_00830 f4aafa06a0e94ea8c07b59d1f35a498e 278 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 137 154 - T 23-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 A0127_00830 f4aafa06a0e94ea8c07b59d1f35a498e 278 Pfam PF00248 Aldo/keto reductase family 21 274 2.6E-61 T 23-10-2018 IPR023210 NADP-dependent oxidoreductase domain A0127_00830 f4aafa06a0e94ea8c07b59d1f35a498e 278 SUPERFAMILY SSF51430 16 272 6.68E-76 T 23-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily A0127_00830 f4aafa06a0e94ea8c07b59d1f35a498e 278 PIRSF PIRSF000097 8 276 2.7E-37 T 23-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 A0127_00830 f4aafa06a0e94ea8c07b59d1f35a498e 278 Gene3D G3DSA:3.20.20.100 9 275 1.6E-88 T 23-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily A0127_05590 4c9c327f6e0e08f5e6a717d74676b9ed 251 Pfam PF03099 Biotin/lipoate A/B protein ligase family 56 159 2.9E-14 T 23-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 A0127_05590 4c9c327f6e0e08f5e6a717d74676b9ed 251 Gene3D G3DSA:3.30.930.10 9 251 7.7E-65 T 23-10-2018 A0127_05590 4c9c327f6e0e08f5e6a717d74676b9ed 251 SUPERFAMILY SSF55681 3 248 2.55E-70 T 23-10-2018 A0127_01810 ea77ddb4af96629d7ae10c48af9d4a78 232 TIGRFAM TIGR00035 asp_race: aspartate racemase 3 229 2.4E-105 T 23-10-2018 IPR004380 Aspartate racemase GO:0006520|GO:0016855 A0127_01810 ea77ddb4af96629d7ae10c48af9d4a78 232 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 81 89 - T 23-10-2018 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A0127_01810 ea77ddb4af96629d7ae10c48af9d4a78 232 SUPERFAMILY SSF53681 4 117 1.96E-36 T 23-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A0127_01810 ea77ddb4af96629d7ae10c48af9d4a78 232 Gene3D G3DSA:3.40.50.1860 107 214 5.4E-89 T 23-10-2018 A0127_01810 ea77ddb4af96629d7ae10c48af9d4a78 232 Pfam PF01177 Asp/Glu/Hydantoin racemase 9 222 1.1E-62 T 23-10-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A0127_01810 ea77ddb4af96629d7ae10c48af9d4a78 232 Gene3D G3DSA:3.40.50.1860 6 220 5.4E-89 T 23-10-2018 A0127_01810 ea77ddb4af96629d7ae10c48af9d4a78 232 SUPERFAMILY SSF53681 119 227 7.52E-26 T 23-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A0127_07520 4da015dd02c3a4edc5c11375263b0b35 114 SUPERFAMILY SSF50249 29 108 4.71E-28 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A0127_07520 4da015dd02c3a4edc5c11375263b0b35 114 Pfam PF00366 Ribosomal protein S17 35 102 4.7E-27 T 23-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A0127_07520 4da015dd02c3a4edc5c11375263b0b35 114 TIGRFAM TIGR03630 uS17_arch: ribosomal protein uS17 4 104 3.0E-47 T 23-10-2018 IPR028333 Ribosomal protein S17, archaeal/eukaryotic Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_07520 4da015dd02c3a4edc5c11375263b0b35 114 PRINTS PR00973 Ribosomal protein S17 family signature 82 92 2.8E-11 T 23-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A0127_07520 4da015dd02c3a4edc5c11375263b0b35 114 PRINTS PR00973 Ribosomal protein S17 family signature 92 99 2.8E-11 T 23-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A0127_07520 4da015dd02c3a4edc5c11375263b0b35 114 PRINTS PR00973 Ribosomal protein S17 family signature 49 72 2.8E-11 T 23-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A0127_07520 4da015dd02c3a4edc5c11375263b0b35 114 Hamap MF_01345_A 30S ribosomal protein S17 [rpsQ]. 2 106 33.033 T 23-10-2018 IPR019978 Ribosomal protein S17, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 A0127_07520 4da015dd02c3a4edc5c11375263b0b35 114 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 31 102 7.0E-35 T 23-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A0127_07520 4da015dd02c3a4edc5c11375263b0b35 114 ProSitePatterns PS00056 Ribosomal protein S17 signature. 82 94 - T 23-10-2018 IPR019979 Ribosomal protein S17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_07520 4da015dd02c3a4edc5c11375263b0b35 114 Gene3D G3DSA:2.40.50.1000 1 113 2.4E-39 T 23-10-2018 A0127_07145 81547343a2927709f26c7d989cbeca50 291 PRINTS PR00410 Phenol hydroxylase reductase family signature 216 224 3.1E-10 T 23-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 A0127_07145 81547343a2927709f26c7d989cbeca50 291 PRINTS PR00410 Phenol hydroxylase reductase family signature 140 149 3.1E-10 T 23-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 A0127_07145 81547343a2927709f26c7d989cbeca50 291 PRINTS PR00410 Phenol hydroxylase reductase family signature 115 134 3.1E-10 T 23-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 A0127_07145 81547343a2927709f26c7d989cbeca50 291 PRINTS PR00410 Phenol hydroxylase reductase family signature 41 53 3.1E-10 T 23-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 A0127_07145 81547343a2927709f26c7d989cbeca50 291 PIRSF PIRSF006816 5 291 2.2E-82 T 23-10-2018 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 A0127_07145 81547343a2927709f26c7d989cbeca50 291 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 140 149 1.7E-7 T 23-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A0127_07145 81547343a2927709f26c7d989cbeca50 291 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 152 163 1.7E-7 T 23-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A0127_07145 81547343a2927709f26c7d989cbeca50 291 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 115 134 1.7E-7 T 23-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A0127_07145 81547343a2927709f26c7d989cbeca50 291 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 216 224 1.7E-7 T 23-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 A0127_07145 81547343a2927709f26c7d989cbeca50 291 SUPERFAMILY SSF63380 4 107 1.22E-22 T 23-10-2018 IPR017938 Riboflavin synthase-like beta-barrel A0127_07145 81547343a2927709f26c7d989cbeca50 291 Gene3D G3DSA:3.40.50.80 106 248 2.1E-22 T 23-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A0127_07145 81547343a2927709f26c7d989cbeca50 291 SUPERFAMILY SSF52343 99 282 1.57E-29 T 23-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A0127_07145 81547343a2927709f26c7d989cbeca50 291 Pfam PF00175 Oxidoreductase NAD-binding domain 116 229 1.9E-12 T 23-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 A0127_07145 81547343a2927709f26c7d989cbeca50 291 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 248 282 7.0E-12 T 23-10-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain A0127_07145 81547343a2927709f26c7d989cbeca50 291 Pfam PF00970 Oxidoreductase FAD-binding domain 17 102 1.9E-8 T 23-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 A0127_07145 81547343a2927709f26c7d989cbeca50 291 Gene3D G3DSA:2.10.240.10 249 283 2.4E-7 T 23-10-2018 IPR037117 Dihydroorotate dehydrogenase, electron transfer subunit, Fe-S binding domain superfamily A0127_07145 81547343a2927709f26c7d989cbeca50 291 Gene3D G3DSA:2.40.30.10 4 103 3.5E-19 T 23-10-2018 A0127_01805 4222d69e45e860dc4268ab8d737fe5bd 325 TIGRFAM TIGR00383 corA: magnesium and cobalt transport protein CorA 9 325 1.4E-88 T 23-10-2018 IPR004488 Magnesium/cobalt transport protein CorA GO:0006824|GO:0015087|GO:0015095|GO:0015693|GO:0016020 A0127_01805 4222d69e45e860dc4268ab8d737fe5bd 325 SUPERFAMILY SSF143865 6 258 1.16E-58 T 23-10-2018 A0127_01805 4222d69e45e860dc4268ab8d737fe5bd 325 Gene3D G3DSA:1.20.58.340 248 325 3.8E-36 T 23-10-2018 A0127_01805 4222d69e45e860dc4268ab8d737fe5bd 325 SUPERFAMILY SSF144083 260 323 1.31E-23 T 23-10-2018 A0127_01805 4222d69e45e860dc4268ab8d737fe5bd 325 Gene3D G3DSA:1.20.58.340 135 246 4.4E-31 T 23-10-2018 A0127_01805 4222d69e45e860dc4268ab8d737fe5bd 325 Gene3D G3DSA:3.30.460.20 1 134 1.2E-23 T 23-10-2018 A0127_01805 4222d69e45e860dc4268ab8d737fe5bd 325 Pfam PF01544 CorA-like Mg2+ transporter protein 38 321 3.1E-69 T 23-10-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 A0127_00490 0dc200ca6ce9c7bb28688a0f53be86ea 421 SUPERFAMILY SSF50475 5 279 2.39E-64 T 23-10-2018 A0127_00490 0dc200ca6ce9c7bb28688a0f53be86ea 421 Gene3D G3DSA:3.40.1670.10 296 408 2.9E-38 T 23-10-2018 A0127_00490 0dc200ca6ce9c7bb28688a0f53be86ea 421 TIGRFAM TIGR00148 TIGR00148: decarboxylase, UbiD family 6 409 7.2E-115 T 23-10-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 A0127_00490 0dc200ca6ce9c7bb28688a0f53be86ea 421 SUPERFAMILY SSF143968 282 419 4.32E-43 T 23-10-2018 A0127_00490 0dc200ca6ce9c7bb28688a0f53be86ea 421 Pfam PF01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 6 385 6.2E-100 T 23-10-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 A0127_04815 398513e05723cc8ce2788d522e8bb215 194 SUPERFAMILY SSF52141 7 192 3.6E-63 T 23-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A0127_04815 398513e05723cc8ce2788d522e8bb215 194 TIGRFAM TIGR00758 UDG_fam4: uracil-DNA glycosylase, family 4 17 192 7.4E-77 T 23-10-2018 IPR005273 Uracil-DNA glycosylase family 4 A0127_04815 398513e05723cc8ce2788d522e8bb215 194 SMART SM00987 31 185 2.0E-38 T 23-10-2018 A0127_04815 398513e05723cc8ce2788d522e8bb215 194 Pfam PF03167 Uracil DNA glycosylase superfamily 31 184 1.6E-47 T 23-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A0127_04815 398513e05723cc8ce2788d522e8bb215 194 Gene3D G3DSA:3.40.470.10 5 192 4.7E-72 T 23-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A0127_04815 398513e05723cc8ce2788d522e8bb215 194 SMART SM00986 31 185 2.0E-38 T 23-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A0127_04785 0a76436e9e9fd1a16ba0d50a5b5c7344 115 Pfam PF03788 LrgA family 15 107 1.9E-27 T 23-10-2018 IPR005538 LrgA/CidA family GO:0016021 A0127_03615 c07a5060f4a660d92089dd9fbfc645ae 112 SUPERFAMILY SSF88697 1 108 3.48E-33 T 23-10-2018 IPR015947 PUA-like superfamily A0127_03615 c07a5060f4a660d92089dd9fbfc645ae 112 Gene3D G3DSA:2.30.130.30 1 112 3.4E-40 T 23-10-2018 A0127_03615 c07a5060f4a660d92089dd9fbfc645ae 112 PIRSF PIRSF016134 2 111 3.1E-47 T 23-10-2018 IPR016645 Uncharacterised conserved protein UCP016134 A0127_03615 c07a5060f4a660d92089dd9fbfc645ae 112 Pfam PF04266 ASCH domain 7 107 1.4E-14 T 23-10-2018 IPR007374 ASCH domain A0127_03615 c07a5060f4a660d92089dd9fbfc645ae 112 SMART SM01022 6 109 9.3E-13 T 23-10-2018 IPR007374 ASCH domain A0127_07680 f3f4b3dcc7bbe2e1dbf78bf9cb120f62 142 TIGRFAM TIGR01077 L13_A_E: ribosomal protein uL13 3 142 3.6E-65 T 23-10-2018 IPR005755 Ribosomal protein L13, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 A0127_07680 f3f4b3dcc7bbe2e1dbf78bf9cb120f62 142 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 1 132 20.523 T 23-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 A0127_07680 f3f4b3dcc7bbe2e1dbf78bf9cb120f62 142 SUPERFAMILY SSF52161 2 142 7.59E-45 T 23-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 A0127_07680 f3f4b3dcc7bbe2e1dbf78bf9cb120f62 142 Gene3D G3DSA:3.90.1180.10 1 142 1.6E-57 T 23-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 A0127_07680 f3f4b3dcc7bbe2e1dbf78bf9cb120f62 142 ProSitePatterns PS00783 Ribosomal protein L13 signature. 79 102 - T 23-10-2018 IPR023563 Ribosomal protein L13, conserved site GO:0003735|GO:0005840|GO:0006412 A0127_07680 f3f4b3dcc7bbe2e1dbf78bf9cb120f62 142 Pfam PF00572 Ribosomal protein L13 3 103 2.8E-11 T 23-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 A0127_07680 f3f4b3dcc7bbe2e1dbf78bf9cb120f62 142 PIRSF PIRSF002181 1 142 5.0E-43 T 23-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 A0127_01095 7816f2f29cbf28e4d13a38472cf8bf76 567 PIRSF PIRSF006553 1 566 1.3E-211 T 23-10-2018 IPR005734 DNA topoisomerase VI, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A0127_01095 7816f2f29cbf28e4d13a38472cf8bf76 567 Gene3D G3DSA:3.30.230.10 353 567 3.9E-73 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A0127_01095 7816f2f29cbf28e4d13a38472cf8bf76 567 SUPERFAMILY SSF54211 353 514 8.34E-61 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A0127_01095 7816f2f29cbf28e4d13a38472cf8bf76 567 Gene3D G3DSA:3.30.565.10 1 232 1.1E-66 T 23-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A0127_01095 7816f2f29cbf28e4d13a38472cf8bf76 567 ProDom PD013790 TOPOISOMERASE ISOMERASE SUBUNIT DNA B VI TYPE II NUCLEOTIDE-BINDING ATP-BINDING 353 550 5.0E-110 T 23-10-2018 IPR015320 DNA topoisomerase VI, subunit B, transducer GO:0003677|GO:0003918|GO:0006265 A0127_01095 7816f2f29cbf28e4d13a38472cf8bf76 567 SUPERFAMILY SSF55874 18 229 1.7E-25 T 23-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily A0127_01095 7816f2f29cbf28e4d13a38472cf8bf76 567 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 32 131 2.7E-11 T 23-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A0127_01095 7816f2f29cbf28e4d13a38472cf8bf76 567 Gene3D G3DSA:1.10.8.50 233 312 2.0E-8 T 23-10-2018 A0127_01095 7816f2f29cbf28e4d13a38472cf8bf76 567 SMART SM00387 31 182 1.6E-8 T 23-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase A0127_01095 7816f2f29cbf28e4d13a38472cf8bf76 567 TIGRFAM TIGR01052 top6b: DNA topoisomerase VI, B subunit 10 533 1.1E-227 T 23-10-2018 IPR005734 DNA topoisomerase VI, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A0127_01095 7816f2f29cbf28e4d13a38472cf8bf76 567 Hamap MF_00322 Type 2 DNA topoisomerase 6 subunit B [top6B]. 8 550 31.58 T 23-10-2018 IPR005734 DNA topoisomerase VI, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 A0127_01095 7816f2f29cbf28e4d13a38472cf8bf76 567 Pfam PF09239 Topoisomerase VI B subunit, transducer 354 509 7.5E-57 T 23-10-2018 IPR015320 DNA topoisomerase VI, subunit B, transducer GO:0003677|GO:0003918|GO:0006265 A0127_04210 2732452ca4d2a30781f27cea4af5a2b8 280 Pfam PF14572 Phosphoribosyl synthetase-associated domain 198 269 5.1E-17 T 23-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 A0127_04210 2732452ca4d2a30781f27cea4af5a2b8 280 Gene3D G3DSA:3.40.50.2020 17 138 1.0E-77 T 23-10-2018 A0127_04210 2732452ca4d2a30781f27cea4af5a2b8 280 Hamap MF_00583_A Putative ribose-phosphate pyrophosphokinase [prs]. 1 278 35.929 T 23-10-2018 IPR037514 Ribose-phosphate pyrophosphokinase, archaea GO:0004749 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 A0127_04210 2732452ca4d2a30781f27cea4af5a2b8 280 Gene3D G3DSA:3.40.50.2020 139 263 1.0E-77 T 23-10-2018 A0127_04210 2732452ca4d2a30781f27cea4af5a2b8 280 SMART SM01400 1 113 1.5E-27 T 23-10-2018 A0127_04210 2732452ca4d2a30781f27cea4af5a2b8 280 SUPERFAMILY SSF53271 62 269 1.95E-38 T 23-10-2018 IPR029057 Phosphoribosyltransferase-like A0127_04210 2732452ca4d2a30781f27cea4af5a2b8 280 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 17 109 8.5E-18 T 23-10-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 A0127_04210 2732452ca4d2a30781f27cea4af5a2b8 280 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 6 277 1.7E-88 T 23-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 A0127_06345 54e1db024c3483d0186415666e9029ad 415 Gene3D G3DSA:1.10.3720.10 160 402 7.7E-48 T 23-10-2018 IPR035906 MetI-like superfamily A0127_06345 54e1db024c3483d0186415666e9029ad 415 SUPERFAMILY SSF161098 176 414 2.49E-54 T 23-10-2018 IPR035906 MetI-like superfamily A0127_06345 54e1db024c3483d0186415666e9029ad 415 SUPERFAMILY SSF161098 8 68 4.8E-5 T 23-10-2018 IPR035906 MetI-like superfamily A0127_06345 54e1db024c3483d0186415666e9029ad 415 Gene3D G3DSA:1.10.3720.10 2 77 8.5E-7 T 23-10-2018 IPR035906 MetI-like superfamily A0127_06345 54e1db024c3483d0186415666e9029ad 415 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 217 401 1.4E-16 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A0127_08590 1bc1857484e3209c8bda303b644d886e 487 Gene3D G3DSA:3.90.1640.10 163 366 2.1E-28 T 23-10-2018 A0127_08590 1bc1857484e3209c8bda303b644d886e 487 Pfam PF02254 TrkA-N domain 3 106 1.1E-17 T 23-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 A0127_08590 1bc1857484e3209c8bda303b644d886e 487 SUPERFAMILY SSF64182 162 453 3.92E-59 T 23-10-2018 IPR038763 DHH phosphoesterase superfamily A0127_08590 1bc1857484e3209c8bda303b644d886e 487 Pfam PF01368 DHH family 166 315 1.6E-11 T 23-10-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 A0127_08590 1bc1857484e3209c8bda303b644d886e 487 Gene3D G3DSA:3.40.50.720 1 140 7.1E-19 T 23-10-2018 A0127_08590 1bc1857484e3209c8bda303b644d886e 487 SUPERFAMILY SSF51735 1 138 2.88E-19 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A0127_08590 1bc1857484e3209c8bda303b644d886e 487 Pfam PF02272 DHHA1 domain 356 474 7.1E-16 T 23-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 A0127_01990 a69d28e5a61f1a41bb1384cdbcbf1119 190 Pfam PF12804 MobA-like NTP transferase domain 6 115 7.0E-14 T 23-10-2018 IPR025877 MobA-like NTP transferase A0127_01990 a69d28e5a61f1a41bb1384cdbcbf1119 190 Gene3D G3DSA:3.90.550.10 5 178 4.0E-28 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A0127_01990 a69d28e5a61f1a41bb1384cdbcbf1119 190 SUPERFAMILY SSF53448 1 177 2.7E-20 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A0127_04435 0ad24ad4b8c46bcc8c7bb740c2603b35 261 TIGRFAM TIGR00259 thylakoid_BtpA: membrane complex biogenesis protein, BtpA family 6 256 2.1E-108 T 23-10-2018 IPR005137 Membrane complex biogenesis protein, BtpA family A0127_04435 0ad24ad4b8c46bcc8c7bb740c2603b35 261 Pfam PF03437 BtpA family 5 254 1.2E-105 T 23-10-2018 IPR005137 Membrane complex biogenesis protein, BtpA family A0127_04435 0ad24ad4b8c46bcc8c7bb740c2603b35 261 SUPERFAMILY SSF51366 21 251 1.55E-27 T 23-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 A0127_04435 0ad24ad4b8c46bcc8c7bb740c2603b35 261 ProDom PD011184 BTPA I PHOTOSYSTEM BIOGENESIS ASSEMBLY SGCQ TRIPHOSPHATASE NUCLEOSIDE PAE3553 ENZYME 28 199 2.0E-86 T 23-10-2018 IPR005137 Membrane complex biogenesis protein, BtpA family A0127_04435 0ad24ad4b8c46bcc8c7bb740c2603b35 261 PIRSF PIRSF005956 1 259 2.0E-96 T 23-10-2018 IPR005137 Membrane complex biogenesis protein, BtpA family A0127_04630 76fcccd966c30e1c66330937fb8956be 218 Pfam PF04256 Protein of unknown function (DUF434) 3 57 7.2E-24 T 23-10-2018 IPR007368 Protein of unknown function DUF434 A0127_04630 76fcccd966c30e1c66330937fb8956be 218 ProDom PD019177 PF1672 MJ0935 ST1363 PH1730 UNCHARACTERIZED ARCHAEAL 1 55 2.0E-22 T 23-10-2018 IPR007368 Protein of unknown function DUF434 A0127_06585 c429e7ec08855025a1993482a9ae5439 113 Gene3D G3DSA:3.40.50.1010 32 112 1.7E-13 T 23-10-2018 A0127_06585 c429e7ec08855025a1993482a9ae5439 113 Pfam PF01850 PIN domain 42 102 1.7E-5 T 23-10-2018 IPR002716 PIN domain A0127_06585 c429e7ec08855025a1993482a9ae5439 113 SUPERFAMILY SSF88723 8 109 7.57E-16 T 23-10-2018 IPR029060 PIN-like domain superfamily A0127_02795 a8d4d379c7daad7b04c4d2151e717f83 466 Pfam PF00890 FAD binding domain 6 348 2.2E-66 T 23-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 A0127_02795 a8d4d379c7daad7b04c4d2151e717f83 466 TIGRFAM TIGR00551 nadB: L-aspartate oxidase 4 448 1.7E-154 T 23-10-2018 IPR005288 L-aspartate oxidase GO:0005737|GO:0008734|GO:0009435|GO:0055114 KEGG: 00250+1.4.3.16|KEGG: 00760+1.4.3.16|MetaCyc: PWY-5316|MetaCyc: PWY-7342 A0127_02795 a8d4d379c7daad7b04c4d2151e717f83 466 Pfam PF02910 Fumarate reductase flavoprotein C-term 428 449 5.8E-6 T 23-10-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A0127_02795 a8d4d379c7daad7b04c4d2151e717f83 466 Gene3D G3DSA:3.50.50.60 6 355 6.8E-110 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A0127_02795 a8d4d379c7daad7b04c4d2151e717f83 466 SUPERFAMILY SSF51905 6 365 3.28E-46 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A0127_02795 a8d4d379c7daad7b04c4d2151e717f83 466 SUPERFAMILY SSF46977 387 453 1.96E-18 T 23-10-2018 IPR037099 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 A0127_02795 a8d4d379c7daad7b04c4d2151e717f83 466 Gene3D G3DSA:3.90.700.10 213 303 6.8E-110 T 23-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 A0127_02795 a8d4d379c7daad7b04c4d2151e717f83 466 SUPERFAMILY SSF56425 205 309 3.89E-32 T 23-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 A0127_02795 a8d4d379c7daad7b04c4d2151e717f83 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 6.7E-7 T 23-10-2018 A0127_02795 a8d4d379c7daad7b04c4d2151e717f83 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 311 333 6.7E-7 T 23-10-2018 A0127_02795 a8d4d379c7daad7b04c4d2151e717f83 466 Gene3D G3DSA:1.20.58.100 370 462 1.3E-19 T 23-10-2018 A0127_01855 f62bdd33f427c947f82c294d25b7f873 615 SUPERFAMILY SSF161098 24 313 2.43E-43 T 23-10-2018 IPR035906 MetI-like superfamily A0127_01855 f62bdd33f427c947f82c294d25b7f873 615 Gene3D G3DSA:1.10.3720.10 336 610 1.0E-38 T 23-10-2018 IPR035906 MetI-like superfamily A0127_01855 f62bdd33f427c947f82c294d25b7f873 615 Gene3D G3DSA:1.10.3720.10 19 320 2.7E-50 T 23-10-2018 IPR035906 MetI-like superfamily A0127_01855 f62bdd33f427c947f82c294d25b7f873 615 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 117 311 1.4E-13 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A0127_01855 f62bdd33f427c947f82c294d25b7f873 615 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 410 603 3.3E-12 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A0127_01855 f62bdd33f427c947f82c294d25b7f873 615 SUPERFAMILY SSF161098 333 608 4.02E-43 T 23-10-2018 IPR035906 MetI-like superfamily A0127_09085 b49c1a462859e327804769c805ab6341 626 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 26 603 1.0E-175 T 23-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A0127_09085 b49c1a462859e327804769c805ab6341 626 ProDom PD016189 SYNTHETASE LIGASE THREONYL-TRNA AMINOACYL-TRNA NUCLEOTIDE-BINDING BIOSYNTHESIS ATP-BINDING ZINC METAL-BINDING THRRS 1 139 8.0E-72 T 23-10-2018 IPR015011 Threonyl-tRNA synthetase, editing domain, archaea GO:0004829|GO:0005524|GO:0005737|GO:0008270 KEGG: 00970+6.1.1.3 A0127_09085 b49c1a462859e327804769c805ab6341 626 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 35 602 29.136 T 23-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A0127_09085 b49c1a462859e327804769c805ab6341 626 SUPERFAMILY SSF52954 504 606 6.49E-32 T 23-10-2018 A0127_09085 b49c1a462859e327804769c805ab6341 626 Gene3D G3DSA:3.40.50.800 504 608 7.2E-34 T 23-10-2018 IPR036621 Anticodon-binding domain superfamily A0127_09085 b49c1a462859e327804769c805ab6341 626 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 288 492 3.6E-19 T 23-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 A0127_09085 b49c1a462859e327804769c805ab6341 626 Gene3D G3DSA:3.30.930.10 203 494 2.4E-63 T 23-10-2018 A0127_09085 b49c1a462859e327804769c805ab6341 626 Gene3D G3DSA:3.50.80.10 1 139 2.7E-58 T 23-10-2018 IPR023509 D-aminoacyl-tRNA deacylase-like superfamily A0127_09085 b49c1a462859e327804769c805ab6341 626 PRINTS PR01047 Threonyl-tRNA synthetase signature 428 456 1.6E-32 T 23-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A0127_09085 b49c1a462859e327804769c805ab6341 626 PRINTS PR01047 Threonyl-tRNA synthetase signature 506 518 1.6E-32 T 23-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A0127_09085 b49c1a462859e327804769c805ab6341 626 PRINTS PR01047 Threonyl-tRNA synthetase signature 471 484 1.6E-32 T 23-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A0127_09085 b49c1a462859e327804769c805ab6341 626 PRINTS PR01047 Threonyl-tRNA synthetase signature 294 322 1.6E-32 T 23-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A0127_09085 b49c1a462859e327804769c805ab6341 626 PRINTS PR01047 Threonyl-tRNA synthetase signature 328 351 1.6E-32 T 23-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 A0127_09085 b49c1a462859e327804769c805ab6341 626 Pfam PF08915 Archaea-specific editing domain of threonyl-tRNA synthetase 1 139 9.6E-57 T 23-10-2018 IPR015011 Threonyl-tRNA synthetase, editing domain, archaea GO:0004829|GO:0005524|GO:0005737|GO:0008270 KEGG: 00970+6.1.1.3 A0127_09085 b49c1a462859e327804769c805ab6341 626 SUPERFAMILY SSF55681 207 489 4.79E-58 T 23-10-2018 A0127_09085 b49c1a462859e327804769c805ab6341 626 Pfam PF03129 Anticodon binding domain 513 602 6.8E-26 T 23-10-2018 IPR004154 Anticodon-binding A0127_00440 128c2d5222c00c7a7b524883df934031 474 SUPERFAMILY SSF52210 143 304 8.37E-45 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A0127_00440 128c2d5222c00c7a7b524883df934031 474 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 167 303 3.0E-57 T 23-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain A0127_00440 128c2d5222c00c7a7b524883df934031 474 Gene3D G3DSA:3.40.50.720 6 140 2.1E-44 T 23-10-2018 A0127_00440 128c2d5222c00c7a7b524883df934031 474 SMART SM00881 12 111 2.6E-36 T 23-10-2018 IPR003781 CoA-binding GO:0048037 A0127_00440 128c2d5222c00c7a7b524883df934031 474 SUPERFAMILY SSF52210 311 468 1.96E-41 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A0127_00440 128c2d5222c00c7a7b524883df934031 474 Gene3D G3DSA:3.40.50.261 308 472 2.5E-51 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A0127_00440 128c2d5222c00c7a7b524883df934031 474 Pfam PF13380 CoA binding domain 16 145 1.3E-25 T 23-10-2018 IPR003781 CoA-binding GO:0048037 A0127_00440 128c2d5222c00c7a7b524883df934031 474 SUPERFAMILY SSF51735 9 141 1.97E-38 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A0127_00440 128c2d5222c00c7a7b524883df934031 474 Gene3D G3DSA:3.40.50.261 142 306 8.2E-61 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A0127_09790 90a45575006ee2087e87753cd7c80e34 67 Pfam PF00037 4Fe-4S binding domain 7 30 3.2E-7 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A0127_09790 90a45575006ee2087e87753cd7c80e34 67 Pfam PF00037 4Fe-4S binding domain 38 58 1.2E-8 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A0127_09790 90a45575006ee2087e87753cd7c80e34 67 Gene3D G3DSA:3.30.70.20 32 66 5.5E-7 T 23-10-2018 A0127_09790 90a45575006ee2087e87753cd7c80e34 67 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 43 54 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A0127_09790 90a45575006ee2087e87753cd7c80e34 67 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 14 25 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A0127_09790 90a45575006ee2087e87753cd7c80e34 67 SUPERFAMILY SSF54862 3 64 5.76E-18 T 23-10-2018 A0127_09790 90a45575006ee2087e87753cd7c80e34 67 Gene3D G3DSA:3.30.70.20 1 31 5.7E-7 T 23-10-2018 A0127_03985 9ceaa7218a4a8d7d333c7f597d4c2302 213 Hamap MF_01200_A Orotidine 5'-phosphate decarboxylase [pyrF]. 6 211 36.773 T 23-10-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A0127_03985 9ceaa7218a4a8d7d333c7f597d4c2302 213 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 58 71 - T 23-10-2018 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A0127_03985 9ceaa7218a4a8d7d333c7f597d4c2302 213 Gene3D G3DSA:3.20.20.70 1 212 3.1E-66 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A0127_03985 9ceaa7218a4a8d7d333c7f597d4c2302 213 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 4 203 2.8E-39 T 23-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A0127_03985 9ceaa7218a4a8d7d333c7f597d4c2302 213 TIGRFAM TIGR01740 pyrF: orotidine 5'-phosphate decarboxylase 6 203 8.5E-50 T 23-10-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A0127_03985 9ceaa7218a4a8d7d333c7f597d4c2302 213 SMART SM00934 5 205 2.4E-64 T 23-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A0127_03985 9ceaa7218a4a8d7d333c7f597d4c2302 213 SUPERFAMILY SSF51366 2 211 2.23E-61 T 23-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 A0127_04450 571b4e3a35d9ed0d3de67d3dc8a5221f 219 Pfam PF03192 Pyrococcus protein of unknown function, DUF257 8 208 4.5E-69 T 23-10-2018 IPR005489 Protein of unknown function DUF257 A0127_04450 571b4e3a35d9ed0d3de67d3dc8a5221f 219 Gene3D G3DSA:3.40.50.11570 2 214 2.2E-62 T 23-10-2018 A0127_06435 8ca14b25e0c8a863bb23165a5f7e2bc3 482 Gene3D G3DSA:3.20.20.70 124 423 1.7E-48 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A0127_06435 8ca14b25e0c8a863bb23165a5f7e2bc3 482 Pfam PF13353 4Fe-4S single cluster domain 131 238 8.1E-8 T 23-10-2018 A0127_06435 8ca14b25e0c8a863bb23165a5f7e2bc3 482 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 373 465 8.8E-7 T 23-10-2018 IPR023885 4Fe4S-binding SPASM domain A0127_06435 8ca14b25e0c8a863bb23165a5f7e2bc3 482 Pfam PF04055 Radical SAM superfamily 131 278 3.3E-19 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A0127_06435 8ca14b25e0c8a863bb23165a5f7e2bc3 482 Pfam PF13186 Iron-sulfur cluster-binding domain 373 438 2.6E-8 T 23-10-2018 IPR023885 4Fe4S-binding SPASM domain A0127_06435 8ca14b25e0c8a863bb23165a5f7e2bc3 482 SUPERFAMILY SSF102114 127 441 1.12E-53 T 23-10-2018 A0127_00820 098597006a2664df99f6249b361f011d 411 Pfam PF10143 2,3-bisphosphoglycerate-independent phosphoglycerate mutase 40 208 4.8E-54 T 23-10-2018 IPR004456 2,3-bisphosphoglycerate-independent phosphoglycerate mutase GO:0003824|GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A0127_00820 098597006a2664df99f6249b361f011d 411 Pfam PF01676 Metalloenzyme superfamily 5 400 7.2E-55 T 23-10-2018 IPR006124 Metalloenzyme GO:0003824|GO:0046872 A0127_00820 098597006a2664df99f6249b361f011d 411 PIRSF PIRSF006392 1 407 2.1E-156 T 23-10-2018 IPR004456 2,3-bisphosphoglycerate-independent phosphoglycerate mutase GO:0003824|GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A0127_00820 098597006a2664df99f6249b361f011d 411 Gene3D G3DSA:3.40.720.10 7 397 4.7E-144 T 23-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 A0127_00820 098597006a2664df99f6249b361f011d 411 TIGRFAM TIGR00306 apgM: phosphoglycerate mutase (2,3-diphosphoglycerate-independent), archaeal form 7 401 2.3E-137 T 23-10-2018 IPR004456 2,3-bisphosphoglycerate-independent phosphoglycerate mutase GO:0003824|GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A0127_00820 098597006a2664df99f6249b361f011d 411 SUPERFAMILY SSF53649 5 404 1.53E-46 T 23-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 A0127_00820 098597006a2664df99f6249b361f011d 411 Hamap MF_01402_A 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [apgM]. 4 402 45.837 T 23-10-2018 IPR023665 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, prokaryotes GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A0127_00820 098597006a2664df99f6249b361f011d 411 Gene3D G3DSA:3.30.70.2130 81 230 4.7E-144 T 23-10-2018 A0127_00085 d6862d7da0f522b7746600fc27f660d9 378 SUPERFAMILY SSF56796 2 377 2.22E-100 T 23-10-2018 A0127_00085 d6862d7da0f522b7746600fc27f660d9 378 Gene3D G3DSA:1.20.1090.10 184 378 7.4E-56 T 23-10-2018 A0127_00085 d6862d7da0f522b7746600fc27f660d9 378 Pfam PF00465 Iron-containing alcohol dehydrogenase 6 367 5.7E-101 T 23-10-2018 IPR001670 Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 A0127_00085 d6862d7da0f522b7746600fc27f660d9 378 Gene3D G3DSA:3.40.50.1970 1 183 2.8E-43 T 23-10-2018 A0127_07390 01a069ce6a0c4cc966230af70c7cd23a 306 PIRSF PIRSF004976 1 305 2.8E-95 T 23-10-2018 IPR035107 tRNA thiolation protein, TtcA/Ctu1 type GO:0008033 Reactome: R-HSA-6782315 A0127_07390 01a069ce6a0c4cc966230af70c7cd23a 306 TIGRFAM TIGR00269 TIGR00269: TIGR00269 family protein 194 294 9.0E-27 T 23-10-2018 IPR000541 Cytoplasmic tRNA 2-thiolation protein 1 GO:0000049|GO:0002098|GO:0034227 Reactome: R-HSA-6782315 A0127_07390 01a069ce6a0c4cc966230af70c7cd23a 306 Pfam PF01171 PP-loop family 51 223 2.7E-13 T 23-10-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 A0127_07390 01a069ce6a0c4cc966230af70c7cd23a 306 Gene3D G3DSA:3.40.50.620 3 306 6.0E-91 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A0127_07390 01a069ce6a0c4cc966230af70c7cd23a 306 SUPERFAMILY SSF52402 27 247 9.04E-50 T 23-10-2018 A0127_05145 7a4e9379fc46e85a25fe0bc48ea9109a 310 Pfam PF01244 Membrane dipeptidase (Peptidase family M19) 2 307 9.8E-93 T 23-10-2018 IPR008257 Peptidase M19 GO:0006508|GO:0016805 MetaCyc: PWY-7533|Reactome: R-HSA-2142691|Reactome: R-HSA-5423646 A0127_05145 7a4e9379fc46e85a25fe0bc48ea9109a 310 SUPERFAMILY SSF51556 1 309 1.08E-73 T 23-10-2018 IPR032466 Metal-dependent hydrolase A0127_05145 7a4e9379fc46e85a25fe0bc48ea9109a 310 ProSitePatterns PS00869 Renal dipeptidase active site. 99 121 - T 23-10-2018 IPR000180 Membrane dipeptidase, active site GO:0006508|GO:0008235|GO:0008239|GO:0016805 MetaCyc: PWY-7533|Reactome: R-HSA-2142691|Reactome: R-HSA-5423646 A0127_05145 7a4e9379fc46e85a25fe0bc48ea9109a 310 Gene3D G3DSA:3.20.20.140 1 310 5.3E-94 T 23-10-2018 A0127_00665 91c9ae61ced989b9eb1b2733fdfb98f3 164 SMART SM00116 24 72 3.9 T 23-10-2018 IPR000644 CBS domain A0127_00665 91c9ae61ced989b9eb1b2733fdfb98f3 164 SMART SM00116 105 152 3.5E-4 T 23-10-2018 IPR000644 CBS domain A0127_00665 91c9ae61ced989b9eb1b2733fdfb98f3 164 SUPERFAMILY SSF54631 6 152 3.54E-21 T 23-10-2018 A0127_00665 91c9ae61ced989b9eb1b2733fdfb98f3 164 Gene3D G3DSA:3.10.580.10 1 76 3.1E-7 T 23-10-2018 A0127_00665 91c9ae61ced989b9eb1b2733fdfb98f3 164 Pfam PF00571 CBS domain 99 152 2.8E-7 T 23-10-2018 IPR000644 CBS domain A0127_00665 91c9ae61ced989b9eb1b2733fdfb98f3 164 Pfam PF00571 CBS domain 24 72 3.2E-5 T 23-10-2018 IPR000644 CBS domain A0127_00665 91c9ae61ced989b9eb1b2733fdfb98f3 164 Gene3D G3DSA:3.10.580.10 81 156 1.7E-11 T 23-10-2018 A0127_00380 978bd67ae8437cd365c90855bfe13b0b 245 TIGRFAM TIGR01969 minD_arch: cell division ATPase MinD 4 236 6.6E-103 T 23-10-2018 IPR010224 ATP binding protein MinD, archaea A0127_00380 978bd67ae8437cd365c90855bfe13b0b 245 PIRSF PIRSF003092 1 241 8.6E-57 T 23-10-2018 IPR025501 ATP binding protein MinD A0127_00380 978bd67ae8437cd365c90855bfe13b0b 245 Pfam PF13614 AAA domain 3 145 8.3E-31 T 23-10-2018 IPR025669 AAA domain A0127_00380 978bd67ae8437cd365c90855bfe13b0b 245 SUPERFAMILY SSF52540 1 235 1.14E-64 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_00380 978bd67ae8437cd365c90855bfe13b0b 245 Gene3D G3DSA:3.40.50.300 1 236 3.9E-77 T 23-10-2018 A0127_07790 c548805f7aef1518dfb94f232a151b4b 447 Gene3D G3DSA:3.50.50.60 5 333 1.9E-118 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A0127_07790 c548805f7aef1518dfb94f232a151b4b 447 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 6.6E-26 T 23-10-2018 A0127_07790 c548805f7aef1518dfb94f232a151b4b 447 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 98 116 6.6E-26 T 23-10-2018 A0127_07790 c548805f7aef1518dfb94f232a151b4b 447 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 144 162 6.6E-26 T 23-10-2018 A0127_07790 c548805f7aef1518dfb94f232a151b4b 447 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 227 243 6.6E-26 T 23-10-2018 A0127_07790 c548805f7aef1518dfb94f232a151b4b 447 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 253 275 6.6E-26 T 23-10-2018 A0127_07790 c548805f7aef1518dfb94f232a151b4b 447 Gene3D G3DSA:3.50.50.60 107 423 1.9E-118 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A0127_07790 c548805f7aef1518dfb94f232a151b4b 447 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 327 424 4.8E-17 T 23-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 A0127_07790 c548805f7aef1518dfb94f232a151b4b 447 SUPERFAMILY SSF51905 1 306 1.92E-46 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A0127_07790 c548805f7aef1518dfb94f232a151b4b 447 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 295 2.1E-54 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A0127_07790 c548805f7aef1518dfb94f232a151b4b 447 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 2.8E-21 T 23-10-2018 A0127_07790 c548805f7aef1518dfb94f232a151b4b 447 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 144 169 2.8E-21 T 23-10-2018 A0127_07790 c548805f7aef1518dfb94f232a151b4b 447 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 268 275 2.8E-21 T 23-10-2018 A0127_07790 c548805f7aef1518dfb94f232a151b4b 447 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 228 242 2.8E-21 T 23-10-2018 A0127_07790 c548805f7aef1518dfb94f232a151b4b 447 SUPERFAMILY SSF55424 318 441 2.58E-24 T 23-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 A0127_06875 5bca1ed51a4714fdfaf144865957b68f 333 TIGRFAM TIGR03972 rSAM_TYW1: wyosine biosynthesis protein TYW1 17 314 1.2E-130 T 23-10-2018 IPR023993 S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase, archaea GO:0008033|GO:0016829|GO:0051539 MetaCyc: PWY-7285|MetaCyc: PWY-7286 A0127_06875 5bca1ed51a4714fdfaf144865957b68f 333 Gene3D G3DSA:3.20.20.70 3 333 3.1E-135 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A0127_06875 5bca1ed51a4714fdfaf144865957b68f 333 Hamap MF_01921 S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase [taw1]. 15 316 49.897 T 23-10-2018 IPR023993 S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase, archaea GO:0008033|GO:0016829|GO:0051539 MetaCyc: PWY-7285|MetaCyc: PWY-7286 A0127_06875 5bca1ed51a4714fdfaf144865957b68f 333 Pfam PF08608 Wyosine base formation 255 315 1.3E-22 T 23-10-2018 IPR013917 tRNA wybutosine-synthesis MetaCyc: PWY-7285|MetaCyc: PWY-7286 A0127_06875 5bca1ed51a4714fdfaf144865957b68f 333 Pfam PF04055 Radical SAM superfamily 67 252 1.0E-24 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A0127_06875 5bca1ed51a4714fdfaf144865957b68f 333 SUPERFAMILY SSF102114 71 282 4.51E-17 T 23-10-2018 A0127_00915 fabfd7c7813cdcfb31b85f8f03e414ff 247 Pfam PF00005 ABC transporter 17 167 5.0E-23 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A0127_00915 fabfd7c7813cdcfb31b85f8f03e414ff 247 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A0127_00915 fabfd7c7813cdcfb31b85f8f03e414ff 247 SUPERFAMILY SSF52540 2 225 1.13E-48 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_00915 fabfd7c7813cdcfb31b85f8f03e414ff 247 Gene3D G3DSA:3.40.50.300 1 241 4.2E-59 T 23-10-2018 A0127_00915 fabfd7c7813cdcfb31b85f8f03e414ff 247 TIGRFAM TIGR01978 sufC: FeS assembly ATPase SufC 2 237 5.8E-89 T 23-10-2018 IPR010230 FeS cluster assembly SUF system, ATPase SufC GO:0005524 A0127_00915 fabfd7c7813cdcfb31b85f8f03e414ff 247 SMART SM00382 26 217 1.3E-6 T 23-10-2018 IPR003593 AAA+ ATPase domain A0127_00565 eab905d8cc2f4e50e5b9dfb707a97d56 193 Gene3D G3DSA:3.30.2170.10 3 143 5.2E-37 T 23-10-2018 A0127_00565 eab905d8cc2f4e50e5b9dfb707a97d56 193 Pfam PF04493 Endonuclease V 143 181 8.0E-5 T 23-10-2018 IPR007581 Endonuclease V GO:0004519|GO:0006281 A0127_00565 eab905d8cc2f4e50e5b9dfb707a97d56 193 Pfam PF04493 Endonuclease V 15 136 1.5E-33 T 23-10-2018 IPR007581 Endonuclease V GO:0004519|GO:0006281 A0127_00565 eab905d8cc2f4e50e5b9dfb707a97d56 193 Hamap MF_00801 Endonuclease V [nfi]. 5 190 26.666 T 23-10-2018 IPR007581 Endonuclease V GO:0004519|GO:0006281 A0127_00565 eab905d8cc2f4e50e5b9dfb707a97d56 193 Gene3D G3DSA:3.30.2170.10 144 192 3.9E-7 T 23-10-2018 A0127_08400 608f6fd3279a90d9c3b1e6ceab73c6b6 174 Pfam PF00210 Ferritin-like domain 7 142 3.4E-44 T 23-10-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 A0127_08400 608f6fd3279a90d9c3b1e6ceab73c6b6 174 Gene3D G3DSA:1.20.1260.10 1 168 6.7E-53 T 23-10-2018 IPR012347 Ferritin-like A0127_08400 608f6fd3279a90d9c3b1e6ceab73c6b6 174 SUPERFAMILY SSF47240 1 160 1.15E-58 T 23-10-2018 IPR009078 Ferritin-like superfamily A0127_03975 bf1d58a4ebfec1d2167426df2fae428c 382 Pfam PF01658 Myo-inositol-1-phosphate synthase 212 317 7.6E-20 T 23-10-2018 IPR013021 Myo-inositol-1-phosphate synthase, GAPDH-like KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 A0127_03975 bf1d58a4ebfec1d2167426df2fae428c 382 SUPERFAMILY SSF55347 211 316 1.83E-28 T 23-10-2018 A0127_03975 bf1d58a4ebfec1d2167426df2fae428c 382 PIRSF PIRSF015578 1 379 7.4E-98 T 23-10-2018 IPR002587 Myo-inositol-1-phosphate synthase GO:0004512|GO:0006021|GO:0008654 KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 A0127_03975 bf1d58a4ebfec1d2167426df2fae428c 382 SUPERFAMILY SSF51735 1 379 4.65E-76 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A0127_03975 bf1d58a4ebfec1d2167426df2fae428c 382 Pfam PF07994 Myo-inositol-1-phosphate synthase 121 354 5.0E-9 T 23-10-2018 IPR002587 Myo-inositol-1-phosphate synthase GO:0004512|GO:0006021|GO:0008654 KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 A0127_03975 bf1d58a4ebfec1d2167426df2fae428c 382 Gene3D G3DSA:3.30.360.10 216 319 3.4E-137 T 23-10-2018 A0127_03975 bf1d58a4ebfec1d2167426df2fae428c 382 Gene3D G3DSA:3.40.50.720 3 354 3.4E-137 T 23-10-2018 A0127_07705 191b9690639cf28d4f015a9a12b929ca 341 Gene3D G3DSA:3.30.390.10 1 112 3.3E-21 T 23-10-2018 IPR029017 Enolase-like, N-terminal A0127_07705 191b9690639cf28d4f015a9a12b929ca 341 Pfam PF03952 Enolase, N-terminal domain 38 119 3.9E-23 T 23-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A0127_07705 191b9690639cf28d4f015a9a12b929ca 341 Gene3D G3DSA:3.20.20.120 218 339 2.6E-13 T 23-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily A0127_07705 191b9690639cf28d4f015a9a12b929ca 341 SMART SM01192 124 340 9.2E-12 T 23-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A0127_07705 191b9690639cf28d4f015a9a12b929ca 341 PRINTS PR00148 Enolase signature 92 108 9.1E-5 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A0127_07705 191b9690639cf28d4f015a9a12b929ca 341 PRINTS PR00148 Enolase signature 316 330 9.1E-5 T 23-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A0127_07705 191b9690639cf28d4f015a9a12b929ca 341 SUPERFAMILY SSF51604 113 337 4.55E-32 T 23-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily A0127_07705 191b9690639cf28d4f015a9a12b929ca 341 Pfam PF00113 Enolase, C-terminal TIM barrel domain 246 334 2.0E-7 T 23-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A0127_07705 191b9690639cf28d4f015a9a12b929ca 341 SUPERFAMILY SSF54826 1 123 7.07E-31 T 23-10-2018 A0127_07705 191b9690639cf28d4f015a9a12b929ca 341 SMART SM01193 4 119 8.4E-36 T 23-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 A0127_01845 1d4899e6d2daeec3c1819e0306560cd0 185 Gene3D G3DSA:1.20.58.290 58 169 6.6E-9 T 23-10-2018 A0127_01845 1d4899e6d2daeec3c1819e0306560cd0 185 SUPERFAMILY SSF50475 3 179 3.61E-31 T 23-10-2018 A0127_01845 1d4899e6d2daeec3c1819e0306560cd0 185 Pfam PF04289 Protein of unknown function (DUF447) 11 179 7.0E-31 T 23-10-2018 IPR007386 Protein of unknown function DUF447 A0127_01845 1d4899e6d2daeec3c1819e0306560cd0 185 PIRSF PIRSF018747 2 185 9.6E-40 T 23-10-2018 IPR016733 Uncharacterised conserved protein UCP018747 A0127_01845 1d4899e6d2daeec3c1819e0306560cd0 185 Gene3D G3DSA:2.30.110.10 18 128 6.6E-9 T 23-10-2018 IPR012349 FMN-binding split barrel GO:0048037 A0127_03330 8669fb2b937c3e2a7505ed087698a0dc 138 PIRSF PIRSF006606 3 135 1.9E-43 T 23-10-2018 IPR007154 Protein of unknown function DUF356 A0127_03330 8669fb2b937c3e2a7505ed087698a0dc 138 Pfam PF04009 Protein of unknown function (DUF356) 5 110 6.2E-36 T 23-10-2018 IPR007154 Protein of unknown function DUF356 A0127_00305 121f7d25a1205564d737f139e6945dd4 217 Gene3D G3DSA:3.40.50.1000 5 134 2.5E-10 T 23-10-2018 IPR023214 HAD superfamily A0127_00305 121f7d25a1205564d737f139e6945dd4 217 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 103 6.1E-6 T 23-10-2018 A0127_00305 121f7d25a1205564d737f139e6945dd4 217 Gene3D G3DSA:1.10.150.520 15 84 2.5E-10 T 23-10-2018 A0127_00305 121f7d25a1205564d737f139e6945dd4 217 SUPERFAMILY SSF56784 4 186 4.2E-14 T 23-10-2018 IPR036412 HAD-like superfamily A0127_04555 896febb09d984604ac5f58b03677ed7b 119 SUPERFAMILY SSF46785 15 115 2.24E-22 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A0127_04555 896febb09d984604ac5f58b03677ed7b 119 Pfam PF03551 Transcriptional regulator PadR-like family 26 99 6.8E-22 T 23-10-2018 IPR005149 Transcription regulator PadR, N-terminal A0127_04555 896febb09d984604ac5f58b03677ed7b 119 Gene3D G3DSA:1.10.10.10 3 118 2.3E-27 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A0127_08065 7c5b23a7cd90076f833d69af57b7512d 106 Gene3D G3DSA:1.10.10.1410 1 58 3.0E-31 T 23-10-2018 IPR038716 Ribosomal protein P1/P2, N-terminal domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_08065 7c5b23a7cd90076f833d69af57b7512d 106 Hamap MF_01478 50S ribosomal protein L12 [rpl12]. 1 103 14.664 T 23-10-2018 IPR027534 Ribosomal protein L12 family GO:0003735|GO:0005622|GO:0005840|GO:0006414 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_08065 7c5b23a7cd90076f833d69af57b7512d 106 Pfam PF00428 60s Acidic ribosomal protein 16 105 1.1E-19 T 23-10-2018 A0127_08065 7c5b23a7cd90076f833d69af57b7512d 106 TIGRFAM TIGR03685 ribo_P1_arch: 50S ribosomal protein P1 1 106 1.6E-41 T 23-10-2018 IPR022295 Ribosomal protein L12, archaea GO:0003735|GO:0005840|GO:0006414 A0127_02260 3c10e8d56584bdde3343fa2f1d9dc3e7 251 PRINTS PR00419 Adrenodoxin reductase family signature 25 47 7.8E-7 T 23-10-2018 A0127_02260 3c10e8d56584bdde3343fa2f1d9dc3e7 251 PRINTS PR00419 Adrenodoxin reductase family signature 48 61 7.8E-7 T 23-10-2018 A0127_02260 3c10e8d56584bdde3343fa2f1d9dc3e7 251 TIGRFAM TIGR00292 TIGR00292: thiazole biosynthesis enzyme 3 249 4.6E-91 T 23-10-2018 IPR002922 Thiazole biosynthetic enzyme Thi4 family A0127_02260 3c10e8d56584bdde3343fa2f1d9dc3e7 251 SUPERFAMILY SSF51905 2 242 1.8E-45 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A0127_02260 3c10e8d56584bdde3343fa2f1d9dc3e7 251 Gene3D G3DSA:3.50.50.60 1 251 1.2E-98 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A0127_02260 3c10e8d56584bdde3343fa2f1d9dc3e7 251 Hamap MF_00304 Thiamine thiazole synthase [thi4]. 1 250 43.571 T 23-10-2018 IPR022828 Thiazole biosynthetic enzyme, prokaryotic A0127_02260 3c10e8d56584bdde3343fa2f1d9dc3e7 251 Pfam PF01946 Thi4 family 7 231 3.9E-77 T 23-10-2018 A0127_02965 237299d9cf6b6b33ba125514dc5c272c 429 TIGRFAM TIGR01142 purT: phosphoribosylglycinamide formyltransferase 2 18 410 1.1E-185 T 23-10-2018 IPR005862 Formate-dependent phosphoribosylglycinamide formyltransferase GO:0000287|GO:0004644|GO:0005524|GO:0009152|GO:0016742 A0127_02965 237299d9cf6b6b33ba125514dc5c272c 429 SUPERFAMILY SSF51246 339 410 1.07E-16 T 23-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 A0127_02965 237299d9cf6b6b33ba125514dc5c272c 429 Gene3D G3DSA:3.30.470.20 201 429 4.1E-78 T 23-10-2018 A0127_02965 237299d9cf6b6b33ba125514dc5c272c 429 Gene3D G3DSA:3.40.50.20 1 128 6.2E-56 T 23-10-2018 A0127_02965 237299d9cf6b6b33ba125514dc5c272c 429 Hamap MF_01643 Formate-dependent phosphoribosylglycinamide formyltransferase [purT]. 12 411 48.72 T 23-10-2018 IPR005862 Formate-dependent phosphoribosylglycinamide formyltransferase GO:0000287|GO:0004644|GO:0005524|GO:0009152|GO:0016742 A0127_02965 237299d9cf6b6b33ba125514dc5c272c 429 SUPERFAMILY SSF52440 8 115 9.64E-34 T 23-10-2018 IPR016185 Pre-ATP-grasp domain superfamily A0127_02965 237299d9cf6b6b33ba125514dc5c272c 429 Gene3D G3DSA:3.30.1490.20 129 200 6.8E-32 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 A0127_02965 237299d9cf6b6b33ba125514dc5c272c 429 SUPERFAMILY SSF56059 118 324 4.24E-51 T 23-10-2018 A0127_02965 237299d9cf6b6b33ba125514dc5c272c 429 Pfam PF02222 ATP-grasp domain 127 303 1.2E-55 T 23-10-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type A0127_08045 9ddfaa5424fd3533e41746e556555a2e 152 TIGRFAM TIGR00405 KOW_elon_Spt5: transcription elongation factor Spt5 7 150 2.9E-51 T 23-10-2018 IPR011590 Transcription elongation factor Spt5, archaeal GO:0003746 A0127_08045 9ddfaa5424fd3533e41746e556555a2e 152 Gene3D G3DSA:2.30.30.30 88 152 2.7E-28 T 23-10-2018 IPR014722 Ribosomal protein L2, domain 2 A0127_08045 9ddfaa5424fd3533e41746e556555a2e 152 Hamap MF_00950 Transcription elongation factor Spt5 [spt5]. 5 148 38.457 T 23-10-2018 IPR011590 Transcription elongation factor Spt5, archaeal GO:0003746 A0127_08045 9ddfaa5424fd3533e41746e556555a2e 152 SMART SM00738 3 87 3.1E-19 T 23-10-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 A0127_08045 9ddfaa5424fd3533e41746e556555a2e 152 Pfam PF00467 KOW motif 95 126 6.9E-9 T 23-10-2018 IPR005824 KOW A0127_08045 9ddfaa5424fd3533e41746e556555a2e 152 SMART SM00739 92 119 3.1E-7 T 23-10-2018 IPR005824 KOW A0127_08045 9ddfaa5424fd3533e41746e556555a2e 152 Gene3D G3DSA:3.30.70.940 2 87 9.0E-33 T 23-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 A0127_08045 9ddfaa5424fd3533e41746e556555a2e 152 Pfam PF03439 Early transcription elongation factor of RNA pol II, NGN section 5 84 2.1E-24 T 23-10-2018 IPR005100 NGN domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 A0127_08045 9ddfaa5424fd3533e41746e556555a2e 152 SUPERFAMILY SSF50104 54 147 2.07E-18 T 23-10-2018 IPR008991 Translation protein SH3-like domain superfamily A0127_00585 9771e9a1262734d57ffd77c6acc3113b 122 SUPERFAMILY SSF47819 1 115 3.31E-26 T 23-10-2018 IPR010997 HRDC-like superfamily GO:0000166|GO:0003824|GO:0044237 A0127_00585 9771e9a1262734d57ffd77c6acc3113b 122 Pfam PF03874 RNA polymerase Rpb4 12 119 2.6E-7 T 23-10-2018 IPR005574 RNA polymerase subunit RPB4/RPC9 GO:0006352|GO:0030880 A0127_00585 9771e9a1262734d57ffd77c6acc3113b 122 Gene3D G3DSA:1.10.287.420 1 54 3.4E-38 T 23-10-2018 A0127_00585 9771e9a1262734d57ffd77c6acc3113b 122 PIRSF PIRSF005053 1 120 1.7E-33 T 23-10-2018 IPR010924 DNA-directed RNA polymerase subunit F (Rpo4) A0127_00585 9771e9a1262734d57ffd77c6acc3113b 122 Gene3D G3DSA:1.10.150.80 55 122 9.6E-31 T 23-10-2018 A0127_10305 4427ff298d0d8356dbbf38bad3880cbb 189 SUPERFAMILY SSF52833 1 188 1.01E-62 T 23-10-2018 IPR036249 Thioredoxin-like superfamily A0127_10305 4427ff298d0d8356dbbf38bad3880cbb 189 PIRSF PIRSF000239 1 189 3.9E-65 T 23-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A0127_10305 4427ff298d0d8356dbbf38bad3880cbb 189 Pfam PF00578 AhpC/TSA family 4 135 2.7E-40 T 23-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 A0127_10305 4427ff298d0d8356dbbf38bad3880cbb 189 Gene3D G3DSA:3.40.30.10 1 186 4.0E-67 T 23-10-2018 A0127_03285 f5b15fb5a32bb50f8aba85fea3012e0a 483 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 359 375 3.0E-27 T 23-10-2018 A0127_03285 f5b15fb5a32bb50f8aba85fea3012e0a 483 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 225 243 3.0E-27 T 23-10-2018 A0127_03285 f5b15fb5a32bb50f8aba85fea3012e0a 483 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 119 138 3.0E-27 T 23-10-2018 A0127_03285 f5b15fb5a32bb50f8aba85fea3012e0a 483 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 269 287 3.0E-27 T 23-10-2018 A0127_03285 f5b15fb5a32bb50f8aba85fea3012e0a 483 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 391 413 3.0E-27 T 23-10-2018 A0127_03285 f5b15fb5a32bb50f8aba85fea3012e0a 483 SUPERFAMILY SSF51905 107 432 5.01E-41 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A0127_03285 f5b15fb5a32bb50f8aba85fea3012e0a 483 SUPERFAMILY SSF54292 17 96 1.28E-22 T 23-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 A0127_03285 f5b15fb5a32bb50f8aba85fea3012e0a 483 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 269 294 7.4E-22 T 23-10-2018 A0127_03285 f5b15fb5a32bb50f8aba85fea3012e0a 483 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 228 237 7.4E-22 T 23-10-2018 A0127_03285 f5b15fb5a32bb50f8aba85fea3012e0a 483 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 406 413 7.4E-22 T 23-10-2018 A0127_03285 f5b15fb5a32bb50f8aba85fea3012e0a 483 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 360 374 7.4E-22 T 23-10-2018 A0127_03285 f5b15fb5a32bb50f8aba85fea3012e0a 483 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 118 140 7.4E-22 T 23-10-2018 A0127_03285 f5b15fb5a32bb50f8aba85fea3012e0a 483 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 15 95 9.2E-30 T 23-10-2018 A0127_03285 f5b15fb5a32bb50f8aba85fea3012e0a 483 Gene3D G3DSA:3.50.50.60 118 448 1.3E-60 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A0127_03285 f5b15fb5a32bb50f8aba85fea3012e0a 483 Gene3D G3DSA:3.50.50.60 237 367 1.3E-60 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A0127_03285 f5b15fb5a32bb50f8aba85fea3012e0a 483 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 118 425 1.0E-38 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A0127_03285 f5b15fb5a32bb50f8aba85fea3012e0a 483 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 60 68 - T 23-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 A0127_03285 f5b15fb5a32bb50f8aba85fea3012e0a 483 Gene3D G3DSA:3.10.20.440 4 100 7.1E-34 T 23-10-2018 A0127_05245 f243b2d1a7dd966ae002f4df5c6a37a4 118 Gene3D G3DSA:2.60.120.10 4 117 6.0E-34 T 23-10-2018 IPR014710 RmlC-like jelly roll fold A0127_05245 f243b2d1a7dd966ae002f4df5c6a37a4 118 SUPERFAMILY SSF51182 6 106 1.18E-27 T 23-10-2018 IPR011051 RmlC-like cupin domain superfamily A0127_05245 f243b2d1a7dd966ae002f4df5c6a37a4 118 Pfam PF07883 Cupin domain 38 104 7.9E-16 T 23-10-2018 IPR013096 Cupin 2, conserved barrel A0127_03645 4a274ae80a0ec08d569ba10a559865c6 540 Gene3D G3DSA:1.10.390.40 86 158 2.2E-58 T 23-10-2018 A0127_03645 4a274ae80a0ec08d569ba10a559865c6 540 SUPERFAMILY SSF52540 141 523 4.2E-59 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_03645 4a274ae80a0ec08d569ba10a559865c6 540 Pfam PF00437 Type II/IV secretion system protein 161 413 1.0E-48 T 23-10-2018 IPR001482 Type II/IV secretion system protein A0127_03645 4a274ae80a0ec08d569ba10a559865c6 540 Gene3D G3DSA:3.40.50.300 259 536 1.5E-90 T 23-10-2018 A0127_03645 4a274ae80a0ec08d569ba10a559865c6 540 Gene3D G3DSA:3.30.450.370 50 256 2.2E-58 T 23-10-2018 A0127_02190 56daea56579901b41f42b095b509d99a 375 Pfam PF04055 Radical SAM superfamily 19 175 4.5E-16 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A0127_02190 56daea56579901b41f42b095b509d99a 375 Pfam PF13353 4Fe-4S single cluster domain 21 124 8.6E-7 T 23-10-2018 A0127_02190 56daea56579901b41f42b095b509d99a 375 PIRSF PIRSF037420 9 205 4.3E-30 T 23-10-2018 IPR017200 Coenzyme PQQ synthesis protein E A0127_02190 56daea56579901b41f42b095b509d99a 375 PIRSF PIRSF037420 263 356 1.9E-13 T 23-10-2018 IPR017200 Coenzyme PQQ synthesis protein E A0127_02190 56daea56579901b41f42b095b509d99a 375 Gene3D G3DSA:3.20.20.70 11 299 7.9E-41 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A0127_02190 56daea56579901b41f42b095b509d99a 375 SUPERFAMILY SSF102114 11 329 5.49E-49 T 23-10-2018 A0127_02190 56daea56579901b41f42b095b509d99a 375 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 263 343 2.9E-11 T 23-10-2018 IPR023885 4Fe4S-binding SPASM domain A0127_02190 56daea56579901b41f42b095b509d99a 375 Pfam PF13186 Iron-sulfur cluster-binding domain 264 319 2.2E-5 T 23-10-2018 IPR023885 4Fe4S-binding SPASM domain A0127_01350 576aa4ea1cd7099c49d5dbfab3f3ebf3 256 Pfam PF02361 Cobalt transport protein 10 210 1.5E-27 T 23-10-2018 IPR003339 ABC/ECF transporter, transmembrane component A0127_00465 1676ab955cb0dc4734fdc19cdc39ede0 150 Pfam PF08905 Domain of unknown function (DUF1850) 43 121 2.7E-11 T 23-10-2018 IPR015001 Protein of unknown function DUF1850 A0127_04260 7823a41a31d69a5cce8f653b3ace7cb3 498 SMART SM00382 42 159 1.7E-12 T 23-10-2018 IPR003593 AAA+ ATPase domain A0127_04260 7823a41a31d69a5cce8f653b3ace7cb3 498 Hamap MF_01508 Replication factor C large subunit [rfcL]. 4 441 35.187 T 23-10-2018 IPR023935 Replication factor C, large subunit A0127_04260 7823a41a31d69a5cce8f653b3ace7cb3 498 SUPERFAMILY SSF52540 4 212 1.51E-46 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_04260 7823a41a31d69a5cce8f653b3ace7cb3 498 Gene3D G3DSA:1.10.8.60 160 217 1.1E-10 T 23-10-2018 A0127_04260 7823a41a31d69a5cce8f653b3ace7cb3 498 Gene3D G3DSA:3.40.50.300 4 157 2.2E-38 T 23-10-2018 A0127_04260 7823a41a31d69a5cce8f653b3ace7cb3 498 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 46 155 4.9E-16 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A0127_09550 b4eabc86392d1abb3ff430f03c258032 555 Pfam PF13186 Iron-sulfur cluster-binding domain 402 462 1.1E-11 T 23-10-2018 IPR023885 4Fe4S-binding SPASM domain A0127_09550 b4eabc86392d1abb3ff430f03c258032 555 SUPERFAMILY SSF102114 146 469 6.54E-78 T 23-10-2018 A0127_09550 b4eabc86392d1abb3ff430f03c258032 555 SMART SM00729 147 347 5.8E-24 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A0127_09550 b4eabc86392d1abb3ff430f03c258032 555 Pfam PF13353 4Fe-4S single cluster domain 149 261 1.5E-10 T 23-10-2018 A0127_09550 b4eabc86392d1abb3ff430f03c258032 555 Pfam PF04055 Radical SAM superfamily 152 308 4.8E-30 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A0127_09550 b4eabc86392d1abb3ff430f03c258032 555 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 402 482 7.5E-14 T 23-10-2018 IPR023885 4Fe4S-binding SPASM domain A0127_09550 b4eabc86392d1abb3ff430f03c258032 555 Gene3D G3DSA:3.20.20.70 148 446 1.7E-56 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A0127_09300 93c29484a94c6d01ef5c7b45c6867289 115 PIRSF PIRSF006113 1 115 7.5E-35 T 23-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 A0127_09300 93c29484a94c6d01ef5c7b45c6867289 115 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 5 113 5.3E-28 T 23-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 A0127_09300 93c29484a94c6d01ef5c7b45c6867289 115 Gene3D G3DSA:3.30.479.10 1 115 3.2E-40 T 23-10-2018 IPR038418 6-pyruvoyl tetrahydropterin synthase/QueD superfamily Reactome: R-HSA-1474151 A0127_09300 93c29484a94c6d01ef5c7b45c6867289 115 SUPERFAMILY SSF55620 2 113 8.89E-32 T 23-10-2018 A0127_01345 c45fc75f2badbc72eb48d35077bc2722 262 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A0127_01345 c45fc75f2badbc72eb48d35077bc2722 262 Gene3D G3DSA:3.40.50.300 1 245 1.1E-73 T 23-10-2018 A0127_01345 c45fc75f2badbc72eb48d35077bc2722 262 SMART SM00382 25 210 4.4E-15 T 23-10-2018 IPR003593 AAA+ ATPase domain A0127_01345 c45fc75f2badbc72eb48d35077bc2722 262 Pfam PF00005 ABC transporter 26 161 3.4E-31 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A0127_01345 c45fc75f2badbc72eb48d35077bc2722 262 SUPERFAMILY SSF52540 1 226 1.68E-66 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_07710 527cf693714f3ce7b208d0a3245dcb7d 201 PRINTS PR00395 Ribosomal protein S2 signature 8 26 4.2E-31 T 23-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A0127_07710 527cf693714f3ce7b208d0a3245dcb7d 201 PRINTS PR00395 Ribosomal protein S2 signature 86 103 4.2E-31 T 23-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A0127_07710 527cf693714f3ce7b208d0a3245dcb7d 201 PRINTS PR00395 Ribosomal protein S2 signature 128 139 4.2E-31 T 23-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A0127_07710 527cf693714f3ce7b208d0a3245dcb7d 201 PRINTS PR00395 Ribosomal protein S2 signature 149 163 4.2E-31 T 23-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A0127_07710 527cf693714f3ce7b208d0a3245dcb7d 201 PRINTS PR00395 Ribosomal protein S2 signature 111 128 4.2E-31 T 23-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A0127_07710 527cf693714f3ce7b208d0a3245dcb7d 201 PRINTS PR00395 Ribosomal protein S2 signature 38 47 4.2E-31 T 23-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A0127_07710 527cf693714f3ce7b208d0a3245dcb7d 201 Pfam PF00318 Ribosomal protein S2 12 104 1.6E-10 T 23-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A0127_07710 527cf693714f3ce7b208d0a3245dcb7d 201 Pfam PF00318 Ribosomal protein S2 110 174 7.5E-14 T 23-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A0127_07710 527cf693714f3ce7b208d0a3245dcb7d 201 Gene3D G3DSA:3.40.50.10490 7 201 1.1E-71 T 23-10-2018 A0127_07710 527cf693714f3ce7b208d0a3245dcb7d 201 TIGRFAM TIGR01012 uS2_euk_arch: ribosomal protein uS2 3 197 1.3E-99 T 23-10-2018 IPR005707 Ribosomal protein S2, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_07710 527cf693714f3ce7b208d0a3245dcb7d 201 ProSitePatterns PS00963 Ribosomal protein S2 signature 2. 111 135 - T 23-10-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 A0127_07710 527cf693714f3ce7b208d0a3245dcb7d 201 SUPERFAMILY SSF52313 3 191 1.06E-62 T 23-10-2018 IPR023591 Ribosomal protein S2, flavodoxin-like domain superfamily A0127_07710 527cf693714f3ce7b208d0a3245dcb7d 201 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 8 19 - T 23-10-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 A0127_07710 527cf693714f3ce7b208d0a3245dcb7d 201 Hamap MF_00291_A 30S ribosomal protein S2 [rpsB]. 1 198 49.043 T 23-10-2018 IPR023454 Ribosomal protein S2, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 A0127_09090 f63a873f28dc8a8eaf33aefb280f76da 198 Hamap MF_00975 Exosome complex component Csl4 [csl4]. 12 193 28.215 T 23-10-2018 IPR030850 Exosome complex component Csl4, archaea GO:0000178|GO:0006396 A0127_09090 f63a873f28dc8a8eaf33aefb280f76da 198 SMART SM00316 68 149 8.4E-9 T 23-10-2018 IPR022967 RNA-binding domain, S1 A0127_09090 f63a873f28dc8a8eaf33aefb280f76da 198 Gene3D G3DSA:2.40.50.140 66 155 1.5E-22 T 23-10-2018 A0127_09090 f63a873f28dc8a8eaf33aefb280f76da 198 SUPERFAMILY SSF50249 65 186 2.45E-28 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A0127_09090 f63a873f28dc8a8eaf33aefb280f76da 198 Pfam PF14382 Exosome complex exonuclease RRP4 N-terminal region 12 48 3.0E-9 T 23-10-2018 IPR025721 Exosome complex component, N-terminal domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A0127_09090 f63a873f28dc8a8eaf33aefb280f76da 198 Gene3D G3DSA:2.40.50.100 11 60 1.1E-17 T 23-10-2018 A0127_09090 f63a873f28dc8a8eaf33aefb280f76da 198 Gene3D G3DSA:2.20.70.10 156 189 2.0E-17 T 23-10-2018 A0127_09090 f63a873f28dc8a8eaf33aefb280f76da 198 SUPERFAMILY SSF110324 11 63 2.93E-12 T 23-10-2018 A0127_09090 f63a873f28dc8a8eaf33aefb280f76da 198 Pfam PF10447 Exosome component EXOSC1/CSL4 66 123 7.6E-5 T 23-10-2018 IPR019495 Exosome complex component CSL4, C-terminal GO:0000178|GO:0003723 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A0127_05260 b19bf3fe9ef33d4ebf2bb8992fa1d0f2 148 SUPERFAMILY SSF53163 1 146 1.57E-29 T 23-10-2018 IPR023430 Peptidase HybD-like domain superfamily A0127_05260 b19bf3fe9ef33d4ebf2bb8992fa1d0f2 148 Gene3D G3DSA:3.40.50.1450 1 148 7.8E-35 T 23-10-2018 IPR023430 Peptidase HybD-like domain superfamily A0127_05260 b19bf3fe9ef33d4ebf2bb8992fa1d0f2 148 Pfam PF01750 Hydrogenase maturation protease 30 144 2.0E-19 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 A0127_05260 b19bf3fe9ef33d4ebf2bb8992fa1d0f2 148 TIGRFAM TIGR00072 hydrog_prot: hydrogenase maturation protease 4 145 4.1E-30 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 A0127_08425 4d96ce53e82f7d8ad4b0d767234bcaf9 70 Hamap MF_00292 30S ribosomal protein S28e [rps28e]. 1 67 25.514 T 23-10-2018 IPR000289 Ribosomal protein S28e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_08425 4d96ce53e82f7d8ad4b0d767234bcaf9 70 Pfam PF01200 Ribosomal protein S28e 4 66 1.9E-30 T 23-10-2018 IPR000289 Ribosomal protein S28e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_08425 4d96ce53e82f7d8ad4b0d767234bcaf9 70 Gene3D G3DSA:2.40.50.140 1 70 7.3E-33 T 23-10-2018 A0127_08425 4d96ce53e82f7d8ad4b0d767234bcaf9 70 ProSitePatterns PS00961 Ribosomal protein S28e signature. 58 66 - T 23-10-2018 IPR028626 Ribosomal protein S28e conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_08425 4d96ce53e82f7d8ad4b0d767234bcaf9 70 ProDom PD005541 RIBOSOMAL RIBONUCLEOPROTEIN 40S S28 S28E 30S ACETYLATION S33 S33 CG15527 1 48 6.0E-11 T 23-10-2018 IPR000289 Ribosomal protein S28e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_08425 4d96ce53e82f7d8ad4b0d767234bcaf9 70 SUPERFAMILY SSF50249 3 69 4.17E-26 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A0127_09350 21f18541b9342dd22faf57b500427889 138 Pfam PF08241 Methyltransferase domain 40 129 8.5E-25 T 23-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 A0127_09350 21f18541b9342dd22faf57b500427889 138 Gene3D G3DSA:3.40.50.150 13 134 3.8E-31 T 23-10-2018 A0127_09350 21f18541b9342dd22faf57b500427889 138 SUPERFAMILY SSF53335 20 129 4.1E-30 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A0127_07675 20544bef0c7f07feb24e41308e3996ea 121 Pfam PF17135 Ribosomal protein 60S L18 and 50S L18e 12 120 2.7E-15 T 23-10-2018 IPR021131 Ribosomal protein L18e/L15P A0127_07675 20544bef0c7f07feb24e41308e3996ea 121 SUPERFAMILY SSF52080 6 120 3.79E-30 T 23-10-2018 IPR036227 Ribosomal L18e/L15P superfamily A0127_07675 20544bef0c7f07feb24e41308e3996ea 121 ProSitePatterns PS01106 Ribosomal protein L18e signature. 36 53 - T 23-10-2018 IPR021132 Ribosomal protein L18e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_07675 20544bef0c7f07feb24e41308e3996ea 121 Hamap MF_00329 50S ribosomal protein L18e [rpl18e]. 5 121 30.939 T 23-10-2018 IPR022947 Ribosomal protein L18e, archaea A0127_07675 20544bef0c7f07feb24e41308e3996ea 121 Gene3D G3DSA:3.100.10.10 6 121 2.5E-39 T 23-10-2018 A0127_08520 1086d179f195908de2fc751b7c33e22a 150 Gene3D G3DSA:1.10.10.2700 1 150 5.7E-66 T 23-10-2018 IPR038111 Ribosomal protein S19e domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_08520 1086d179f195908de2fc751b7c33e22a 150 Pfam PF01090 Ribosomal protein S19e 3 138 4.2E-58 T 23-10-2018 IPR001266 Ribosomal protein S19e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_08520 1086d179f195908de2fc751b7c33e22a 150 ProSitePatterns PS00628 Ribosomal protein S19e signature. 87 106 - T 23-10-2018 IPR018277 Ribosomal protein S19e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_08520 1086d179f195908de2fc751b7c33e22a 150 Hamap MF_01474 30S ribosomal protein S19e [rps19e]. 1 148 37.864 T 23-10-2018 IPR027548 Ribosomal protein S19e, archaeal GO:0003735|GO:0005840|GO:0006412 A0127_08520 1086d179f195908de2fc751b7c33e22a 150 SMART SM01413 3 139 1.2E-89 T 23-10-2018 IPR001266 Ribosomal protein S19e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_08520 1086d179f195908de2fc751b7c33e22a 150 ProDom PD003854 RIBOSOMAL 40S RIBONUCLEOPROTEIN S19 S19E 30S MULTIGENE FAMILY S19 SSU 3 115 1.0E-60 T 23-10-2018 IPR001266 Ribosomal protein S19e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_08520 1086d179f195908de2fc751b7c33e22a 150 SUPERFAMILY SSF46785 3 150 4.53E-61 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A0127_06360 4e4de3fab14f049bed5604305dc31d80 341 SUPERFAMILY SSF159071 256 340 3.79E-18 T 23-10-2018 A0127_06360 4e4de3fab14f049bed5604305dc31d80 341 Pfam PF11495 Archaeal transcriptional regulator TrmB 112 339 2.0E-58 T 23-10-2018 IPR021586 Transcription regulator TrmB, C-terminal A0127_06360 4e4de3fab14f049bed5604305dc31d80 341 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 10 77 7.5E-25 T 23-10-2018 IPR002831 Transcription regulator TrmB, N-terminal A0127_06360 4e4de3fab14f049bed5604305dc31d80 341 SUPERFAMILY SSF46785 4 95 1.16E-9 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A0127_06360 4e4de3fab14f049bed5604305dc31d80 341 Gene3D G3DSA:1.10.10.10 3 101 1.2E-29 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A0127_08545 693040e1edd762bc96901e1442fa35cc 294 Pfam PF03186 CobD/Cbib protein 8 268 5.8E-84 T 23-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 A0127_08545 693040e1edd762bc96901e1442fa35cc 294 Hamap MF_00024 Cobalamin biosynthesis protein CbiB [cbiB]. 1 290 76.462 T 23-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 A0127_08545 693040e1edd762bc96901e1442fa35cc 294 TIGRFAM TIGR00380 cobD: cobalamin biosynthesis protein CobD 5 286 4.4E-83 T 23-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 A0127_09150 d26d2a6eed04b14107ead7f1d98c389a 796 Pfam PF02933 Cell division protein 48 (CDC48), domain 2 107 169 1.0E-13 T 23-10-2018 IPR004201 CDC48, domain 2 A0127_09150 d26d2a6eed04b14107ead7f1d98c389a 796 SMART SM01073 8 92 3.7E-45 T 23-10-2018 IPR003338 CDC48, N-terminal subdomain A0127_09150 d26d2a6eed04b14107ead7f1d98c389a 796 SUPERFAMILY SSF54585 92 184 1.9E-20 T 23-10-2018 IPR029067 CDC48 domain 2-like superfamily A0127_09150 d26d2a6eed04b14107ead7f1d98c389a 796 ProSitePatterns PS00674 AAA-protein family signature. 654 672 - T 23-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 A0127_09150 d26d2a6eed04b14107ead7f1d98c389a 796 SUPERFAMILY SSF50692 2 90 1.55E-31 T 23-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily A0127_09150 d26d2a6eed04b14107ead7f1d98c389a 796 Gene3D G3DSA:3.40.50.300 509 683 9.6E-75 T 23-10-2018 A0127_09150 d26d2a6eed04b14107ead7f1d98c389a 796 TIGRFAM TIGR01243 CDC48: AAA family ATPase, CDC48 subfamily 7 794 0.0 T 23-10-2018 IPR005938 AAA ATPase, CDC48 family GO:0016787 Reactome: R-HSA-110320|Reactome: R-HSA-3371511|Reactome: R-HSA-382556|Reactome: R-HSA-532668|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5678895|Reactome: R-HSA-5689877|Reactome: R-HSA-5689896|Reactome: R-HSA-6798695|Reactome: R-HSA-8866654|Reactome: R-HSA-8876725 A0127_09150 d26d2a6eed04b14107ead7f1d98c389a 796 Gene3D G3DSA:2.40.40.20 1 92 1.2E-37 T 23-10-2018 A0127_09150 d26d2a6eed04b14107ead7f1d98c389a 796 SMART SM01072 107 170 3.4E-18 T 23-10-2018 IPR004201 CDC48, domain 2 A0127_09150 d26d2a6eed04b14107ead7f1d98c389a 796 Gene3D G3DSA:1.10.8.60 350 414 1.6E-85 T 23-10-2018 A0127_09150 d26d2a6eed04b14107ead7f1d98c389a 796 SUPERFAMILY SSF52540 179 502 1.46E-70 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_09150 d26d2a6eed04b14107ead7f1d98c389a 796 Gene3D G3DSA:3.10.330.10 93 173 8.4E-8 T 23-10-2018 A0127_09150 d26d2a6eed04b14107ead7f1d98c389a 796 Gene3D G3DSA:3.40.50.300 179 349 1.6E-85 T 23-10-2018 A0127_09150 d26d2a6eed04b14107ead7f1d98c389a 796 SMART SM00382 215 351 4.2E-26 T 23-10-2018 IPR003593 AAA+ ATPase domain A0127_09150 d26d2a6eed04b14107ead7f1d98c389a 796 SMART SM00382 550 686 1.3E-24 T 23-10-2018 IPR003593 AAA+ ATPase domain A0127_09150 d26d2a6eed04b14107ead7f1d98c389a 796 Pfam PF02359 Cell division protein 48 (CDC48), N-terminal domain 8 91 3.3E-36 T 23-10-2018 IPR003338 CDC48, N-terminal subdomain A0127_09150 d26d2a6eed04b14107ead7f1d98c389a 796 Gene3D G3DSA:1.10.8.60 422 506 6.6E-17 T 23-10-2018 A0127_09150 d26d2a6eed04b14107ead7f1d98c389a 796 ProSitePatterns PS00674 AAA-protein family signature. 319 337 - T 23-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 A0127_09150 d26d2a6eed04b14107ead7f1d98c389a 796 Pfam PF09336 Vps4 C terminal oligomerisation domain 750 789 5.2E-5 T 23-10-2018 IPR015415 Vps4 oligomerisation, C-terminal A0127_09150 d26d2a6eed04b14107ead7f1d98c389a 796 Gene3D G3DSA:1.10.8.60 685 793 3.3E-34 T 23-10-2018 A0127_09150 d26d2a6eed04b14107ead7f1d98c389a 796 SUPERFAMILY SSF52540 512 791 2.77E-81 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_09150 d26d2a6eed04b14107ead7f1d98c389a 796 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 554 683 2.7E-49 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A0127_09150 d26d2a6eed04b14107ead7f1d98c389a 796 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 219 348 6.6E-52 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A0127_04295 6baf22acf80868498bc589abf21184c4 592 Pfam PF09378 HAS barrel domain 11 116 7.9E-23 T 23-10-2018 IPR018538 Helicase HerA, barrel domain A0127_04295 6baf22acf80868498bc589abf21184c4 592 SUPERFAMILY SSF52540 148 548 3.02E-40 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_04295 6baf22acf80868498bc589abf21184c4 592 Gene3D G3DSA:3.40.50.300 142 291 4.2E-22 T 23-10-2018 A0127_04295 6baf22acf80868498bc589abf21184c4 592 Pfam PF01935 Domain of unknown function DUF87 156 382 6.6E-54 T 23-10-2018 IPR002789 Helicase HerA, central domain A0127_08915 97b111f6fca4b711748401503fc77943 153 Pfam PF10050 Predicted metal-binding protein (DUF2284) 8 138 4.9E-33 T 23-10-2018 IPR019271 Protein of unknown function DUF2284, metal-binding A0127_08915 97b111f6fca4b711748401503fc77943 153 PIRSF PIRSF018748 1 153 8.3E-58 T 23-10-2018 IPR019271 Protein of unknown function DUF2284, metal-binding A0127_02820 54fd9c21ac72ac6fe3826b63e3c4e6c9 154 Pfam PF01927 Mut7-C RNAse domain 1 144 2.1E-45 T 23-10-2018 IPR002782 Mut7-C RNAse domain A0127_10125 07995303a42e48bae54a70b53c56bcb6 247 SUPERFAMILY SSF52540 5 235 4.92E-65 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_10125 07995303a42e48bae54a70b53c56bcb6 247 Gene3D G3DSA:3.40.50.300 3 243 2.1E-69 T 23-10-2018 A0127_10125 07995303a42e48bae54a70b53c56bcb6 247 ProSitePatterns PS00211 ABC transporters family signature. 153 167 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A0127_10125 07995303a42e48bae54a70b53c56bcb6 247 Pfam PF00005 ABC transporter 25 181 1.9E-33 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A0127_10125 07995303a42e48bae54a70b53c56bcb6 247 SMART SM00382 34 229 1.4E-18 T 23-10-2018 IPR003593 AAA+ ATPase domain A0127_05745 0902eeccda112e495454fb2bb138c6bc 354 Gene3D G3DSA:1.10.150.20 41 103 3.0E-25 T 23-10-2018 A0127_05745 0902eeccda112e495454fb2bb138c6bc 354 SMART SM00382 135 324 1.8E-10 T 23-10-2018 IPR003593 AAA+ ATPase domain A0127_05745 0902eeccda112e495454fb2bb138c6bc 354 Pfam PF08423 Rad51 102 354 3.2E-93 T 23-10-2018 IPR013632 DNA recombination and repair protein Rad51-like, C-terminal Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579 A0127_05745 0902eeccda112e495454fb2bb138c6bc 354 PIRSF PIRSF005856 28 354 1.3E-136 T 23-10-2018 IPR016467 DNA recombination and repair protein, RecA-like Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579 A0127_05745 0902eeccda112e495454fb2bb138c6bc 354 Hamap MF_00348 DNA repair and recombination protein RadA [radA]. 39 354 81.994 T 23-10-2018 IPR011938 DNA recombination/repair protein RadA GO:0003684|GO:0005524|GO:0006281|GO:0006310|GO:0008094 A0127_05745 0902eeccda112e495454fb2bb138c6bc 354 SMART SM00278 40 59 0.038 T 23-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A0127_05745 0902eeccda112e495454fb2bb138c6bc 354 SMART SM00278 73 92 160.0 T 23-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A0127_05745 0902eeccda112e495454fb2bb138c6bc 354 SUPERFAMILY SSF52540 116 353 3.91E-60 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_05745 0902eeccda112e495454fb2bb138c6bc 354 Gene3D G3DSA:3.40.50.300 104 354 1.7E-85 T 23-10-2018 A0127_05745 0902eeccda112e495454fb2bb138c6bc 354 Pfam PF14520 Helix-hairpin-helix domain 41 95 4.0E-12 T 23-10-2018 A0127_05745 0902eeccda112e495454fb2bb138c6bc 354 SUPERFAMILY SSF47794 35 98 7.06E-14 T 23-10-2018 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 A0127_05745 0902eeccda112e495454fb2bb138c6bc 354 TIGRFAM TIGR02236 recomb_radA: DNA repair and recombination protein RadA 42 354 1.9E-165 T 23-10-2018 IPR011938 DNA recombination/repair protein RadA GO:0003684|GO:0005524|GO:0006281|GO:0006310|GO:0008094 A0127_10135 8a6aa5e2bf26ee992a2636de47496ac8 385 PIRSF PIRSF001434 1 384 9.7E-164 T 23-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 A0127_10135 8a6aa5e2bf26ee992a2636de47496ac8 385 SUPERFAMILY SSF53383 40 382 7.8E-133 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A0127_10135 8a6aa5e2bf26ee992a2636de47496ac8 385 Gene3D G3DSA:3.40.640.10 1 248 1.1E-102 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A0127_10135 8a6aa5e2bf26ee992a2636de47496ac8 385 Gene3D G3DSA:3.90.1150.10 249 385 1.6E-62 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A0127_10135 8a6aa5e2bf26ee992a2636de47496ac8 385 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 5 380 3.8E-165 T 23-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 A0127_09335 081868d58f43690f6bb58b24bdadcaba 358 Pfam PF00557 Metallopeptidase family M24 149 350 1.4E-30 T 23-10-2018 IPR000994 Peptidase M24 A0127_09335 081868d58f43690f6bb58b24bdadcaba 358 Gene3D G3DSA:3.40.350.10 8 142 1.5E-19 T 23-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal A0127_09335 081868d58f43690f6bb58b24bdadcaba 358 Gene3D G3DSA:3.90.230.10 143 358 3.8E-43 T 23-10-2018 A0127_09335 081868d58f43690f6bb58b24bdadcaba 358 SUPERFAMILY SSF55920 141 358 6.15E-46 T 23-10-2018 IPR036005 Creatinase/aminopeptidase-like A0127_09335 081868d58f43690f6bb58b24bdadcaba 358 SUPERFAMILY SSF53092 6 141 2.27E-23 T 23-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal A0127_09335 081868d58f43690f6bb58b24bdadcaba 358 Pfam PF01321 Creatinase/Prolidase N-terminal domain 11 142 2.2E-13 T 23-10-2018 IPR000587 Creatinase, N-terminal GO:0016787 A0127_10115 6756acc42c579b03fde4a830d2c09719 228 Gene3D G3DSA:3.40.50.150 24 215 6.2E-37 T 23-10-2018 A0127_10115 6756acc42c579b03fde4a830d2c09719 228 Pfam PF08241 Methyltransferase domain 57 152 2.0E-23 T 23-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 A0127_10115 6756acc42c579b03fde4a830d2c09719 228 SUPERFAMILY SSF53335 22 215 4.22E-38 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A0127_05280 bf12ebadac6e0cb09a29a31cdeda4467 264 Gene3D G3DSA:3.40.50.700 4 163 7.4E-42 T 23-10-2018 IPR037024 [NiFe]-hydrogenase, small subunit, N-terminal domain superfamily A0127_05280 bf12ebadac6e0cb09a29a31cdeda4467 264 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 16 152 1.2E-26 T 23-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A0127_05280 bf12ebadac6e0cb09a29a31cdeda4467 264 SUPERFAMILY SSF56770 4 211 7.06E-47 T 23-10-2018 A0127_00330 ad56e2ed875dcac614eab9de271fe366 335 Gene3D G3DSA:3.30.1330.10 5 146 1.3E-25 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A0127_00330 ad56e2ed875dcac614eab9de271fe366 335 Gene3D G3DSA:3.90.650.10 152 327 1.6E-29 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A0127_00330 ad56e2ed875dcac614eab9de271fe366 335 SUPERFAMILY SSF55326 7 147 2.44E-23 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A0127_00330 ad56e2ed875dcac614eab9de271fe366 335 Pfam PF02769 AIR synthase related protein, C-terminal domain 154 306 9.3E-15 T 23-10-2018 IPR010918 PurM-like, C-terminal domain A0127_00330 ad56e2ed875dcac614eab9de271fe366 335 Pfam PF00586 AIR synthase related protein, N-terminal domain 46 143 2.8E-14 T 23-10-2018 IPR016188 PurM-like, N-terminal domain A0127_00330 ad56e2ed875dcac614eab9de271fe366 335 PIRSF PIRSF005644 2 328 9.1E-64 T 23-10-2018 IPR011854 Carbamoyl dehydratase HypE A0127_00330 ad56e2ed875dcac614eab9de271fe366 335 SUPERFAMILY SSF56042 152 314 2.69E-25 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A0127_07835 8c99a60e23a357a9c83f28dc6a87fc9f 262 Pfam PF00696 Amino acid kinase family 2 233 2.7E-39 T 23-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 A0127_07835 8c99a60e23a357a9c83f28dc6a87fc9f 262 SUPERFAMILY SSF53633 1 261 2.62E-33 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily A0127_07835 8c99a60e23a357a9c83f28dc6a87fc9f 262 PIRSF PIRSF016496 1 262 3.5E-80 T 23-10-2018 IPR024192 Fosfomycin resistance kinase, FomA-type GO:0016301 KEGG: 00900+2.7.4.26|MetaCyc: PWY-6174|MetaCyc: PWY-7524 A0127_07835 8c99a60e23a357a9c83f28dc6a87fc9f 262 Gene3D G3DSA:3.40.1160.10 1 261 4.7E-59 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily A0127_07135 6ec8380a69facf162cf5f836ae88608b 415 Gene3D G3DSA:1.10.645.10 1 411 8.3E-101 T 23-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A0127_07135 6ec8380a69facf162cf5f836ae88608b 415 SUPERFAMILY SSF56762 2 411 9.03E-96 T 23-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A0127_07135 6ec8380a69facf162cf5f836ae88608b 415 Pfam PF00374 Nickel-dependent hydrogenase 39 122 3.3E-13 T 23-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 A0127_07135 6ec8380a69facf162cf5f836ae88608b 415 Pfam PF00374 Nickel-dependent hydrogenase 222 411 2.5E-20 T 23-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 A0127_07135 6ec8380a69facf162cf5f836ae88608b 415 ProSitePatterns PS00508 Nickel-dependent hydrogenases large subunit signature 2. 402 411 - T 23-10-2018 IPR018194 Nickel-dependent hydrogenase, large subunit, nickel binding site GO:0008901|GO:0016151|GO:0055114 A0127_02120 1f802f378fe29a07dd3dae60f5c5510f 493 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 121 140 1.4E-7 T 23-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A0127_02120 1f802f378fe29a07dd3dae60f5c5510f 493 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 151 175 1.4E-7 T 23-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A0127_02120 1f802f378fe29a07dd3dae60f5c5510f 493 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 302 321 1.4E-7 T 23-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A0127_02120 1f802f378fe29a07dd3dae60f5c5510f 493 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 219 243 1.4E-7 T 23-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A0127_02120 1f802f378fe29a07dd3dae60f5c5510f 493 Pfam PF00361 Proton-conducting membrane transporter 115 378 3.4E-53 T 23-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A0127_03370 586550156b11a1e979869227ac3a1e6f 458 SUPERFAMILY SSF52210 292 451 2.09E-40 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A0127_03370 586550156b11a1e979869227ac3a1e6f 458 Pfam PF13380 CoA binding domain 11 134 2.7E-23 T 23-10-2018 IPR003781 CoA-binding GO:0048037 A0127_03370 586550156b11a1e979869227ac3a1e6f 458 Gene3D G3DSA:3.40.50.261 130 289 7.8E-60 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A0127_03370 586550156b11a1e979869227ac3a1e6f 458 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 150 287 5.1E-55 T 23-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain A0127_03370 586550156b11a1e979869227ac3a1e6f 458 SUPERFAMILY SSF52210 132 288 9.94E-45 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A0127_03370 586550156b11a1e979869227ac3a1e6f 458 SUPERFAMILY SSF51735 3 130 3.55E-37 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A0127_03370 586550156b11a1e979869227ac3a1e6f 458 SMART SM00881 6 100 2.9E-32 T 23-10-2018 IPR003781 CoA-binding GO:0048037 A0127_03370 586550156b11a1e979869227ac3a1e6f 458 Gene3D G3DSA:3.40.50.720 3 129 1.3E-44 T 23-10-2018 A0127_03370 586550156b11a1e979869227ac3a1e6f 458 Gene3D G3DSA:3.40.50.261 290 458 3.1E-67 T 23-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 A0127_05555 b4281bc1cf6447227706b467bdbd324c 278 Pfam PF01513 ATP-NAD kinase 2 261 1.2E-71 T 23-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 A0127_05555 b4281bc1cf6447227706b467bdbd324c 278 Hamap MF_00361 NAD kinase [nadK]. 1 276 29.725 T 23-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 A0127_05555 b4281bc1cf6447227706b467bdbd324c 278 Gene3D G3DSA:2.60.200.30 121 254 1.1E-70 T 23-10-2018 IPR017437 ATP-NAD kinase, PpnK-type, C-terminal GO:0003951|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 A0127_05555 b4281bc1cf6447227706b467bdbd324c 278 SUPERFAMILY SSF111331 2 265 6.15E-72 T 23-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily A0127_05555 b4281bc1cf6447227706b467bdbd324c 278 Gene3D G3DSA:3.40.50.10330 20 267 1.1E-70 T 23-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 A0127_04305 7e19f995b9d57daadd0bc61b4bdadba1 883 SUPERFAMILY SSF52540 1 246 2.5E-22 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_04305 7e19f995b9d57daadd0bc61b4bdadba1 883 SUPERFAMILY SSF52540 1 869 5.14E-34 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_04305 7e19f995b9d57daadd0bc61b4bdadba1 883 SUPERFAMILY SSF90257 253 365 2.14E-5 T 23-10-2018 A0127_04305 7e19f995b9d57daadd0bc61b4bdadba1 883 Gene3D G3DSA:1.10.287.510 391 502 1.9E-26 T 23-10-2018 A0127_04305 7e19f995b9d57daadd0bc61b4bdadba1 883 Pfam PF04423 Rad50 zinc hook motif 421 469 1.7E-12 T 23-10-2018 IPR013134 RAD50, zinc hook Reactome: R-HSA-2559586|Reactome: R-HSA-5685938|Reactome: R-HSA-5685939|Reactome: R-HSA-5685942|Reactome: R-HSA-5693548|Reactome: R-HSA-5693554|Reactome: R-HSA-5693565|Reactome: R-HSA-5693568|Reactome: R-HSA-5693571|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 A0127_04305 7e19f995b9d57daadd0bc61b4bdadba1 883 Pfam PF13476 AAA domain 5 285 9.8E-7 T 23-10-2018 IPR038729 Rad50/SbcC-type AAA domain A0127_04305 7e19f995b9d57daadd0bc61b4bdadba1 883 SMART SM00382 22 872 4.9E-4 T 23-10-2018 IPR003593 AAA+ ATPase domain A0127_04305 7e19f995b9d57daadd0bc61b4bdadba1 883 Gene3D G3DSA:3.40.50.300 683 879 1.0E-42 T 23-10-2018 A0127_04305 7e19f995b9d57daadd0bc61b4bdadba1 883 Gene3D G3DSA:3.40.50.300 1 368 4.1E-32 T 23-10-2018 A0127_04305 7e19f995b9d57daadd0bc61b4bdadba1 883 Hamap MF_00449 DNA double-strand break repair Rad50 ATPase [rad50]. 1 879 13.87 T 23-10-2018 IPR022982 DNA double-strand break repair Rad50 ATPase, archaeal type A0127_04305 7e19f995b9d57daadd0bc61b4bdadba1 883 SUPERFAMILY SSF75712 394 491 4.58E-19 T 23-10-2018 A0127_01560 88fe834341f8979b363886405bff295f 548 ProSitePatterns PS00751 Chaperonins TCP-1 signature 2. 61 77 - T 23-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 A0127_01560 88fe834341f8979b363886405bff295f 548 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 373 395 1.6E-34 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 A0127_01560 88fe834341f8979b363886405bff295f 548 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 37 53 1.6E-34 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 A0127_01560 88fe834341f8979b363886405bff295f 548 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 407 419 1.6E-34 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 A0127_01560 88fe834341f8979b363886405bff295f 548 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 89 108 1.6E-34 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 A0127_01560 88fe834341f8979b363886405bff295f 548 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 59 77 1.6E-34 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 A0127_01560 88fe834341f8979b363886405bff295f 548 ProSitePatterns PS00750 Chaperonins TCP-1 signature 1. 40 52 - T 23-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 A0127_01560 88fe834341f8979b363886405bff295f 548 SUPERFAMILY SSF54849 148 405 2.04E-30 T 23-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily A0127_01560 88fe834341f8979b363886405bff295f 548 Gene3D G3DSA:1.10.560.10 28 522 7.3E-219 T 23-10-2018 IPR027413 GroEL-like equatorial domain superfamily A0127_01560 88fe834341f8979b363886405bff295f 548 SUPERFAMILY SSF52029 212 378 9.84E-64 T 23-10-2018 IPR027409 GroEL-like apical domain superfamily A0127_01560 88fe834341f8979b363886405bff295f 548 SUPERFAMILY SSF48592 17 526 1.96E-90 T 23-10-2018 IPR027413 GroEL-like equatorial domain superfamily A0127_01560 88fe834341f8979b363886405bff295f 548 Gene3D G3DSA:3.30.260.10 147 405 7.3E-219 T 23-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily A0127_01560 88fe834341f8979b363886405bff295f 548 Pfam PF00118 TCP-1/cpn60 chaperonin family 35 526 4.9E-182 T 23-10-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 A0127_01560 88fe834341f8979b363886405bff295f 548 TIGRFAM TIGR02339 thermosome_arch: thermosome, various subunits, archaeal 8 525 2.8E-237 T 23-10-2018 IPR012714 Thermosome, archaeal GO:0005524|GO:0006457|GO:0051082 A0127_01560 88fe834341f8979b363886405bff295f 548 ProSitePatterns PS00995 Chaperonins TCP-1 signature 3. 89 97 - T 23-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 A0127_01560 88fe834341f8979b363886405bff295f 548 Gene3D G3DSA:3.50.7.10 218 369 7.3E-219 T 23-10-2018 IPR027409 GroEL-like apical domain superfamily A0127_10245 b6f6de4f76e21da345d83b47ff15d334 118 Pfam PF01022 Bacterial regulatory protein, arsR family 40 85 1.2E-16 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A0127_10245 b6f6de4f76e21da345d83b47ff15d334 118 Gene3D G3DSA:1.10.10.10 1 118 1.9E-35 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A0127_10245 b6f6de4f76e21da345d83b47ff15d334 118 ProSitePatterns PS00846 Bacterial regulatory proteins, arsR family signature. 57 75 - T 23-10-2018 IPR018334 ArsR-type transcription regulator, HTH motif GO:0003700|GO:0005622|GO:0006355 A0127_10245 b6f6de4f76e21da345d83b47ff15d334 118 SMART SM00418 33 112 2.6E-30 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A0127_10245 b6f6de4f76e21da345d83b47ff15d334 118 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 55 66 7.2E-17 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A0127_10245 b6f6de4f76e21da345d83b47ff15d334 118 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 35 50 7.2E-17 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A0127_10245 b6f6de4f76e21da345d83b47ff15d334 118 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 68 83 7.2E-17 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A0127_10245 b6f6de4f76e21da345d83b47ff15d334 118 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 83 98 7.2E-17 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A0127_10245 b6f6de4f76e21da345d83b47ff15d334 118 SUPERFAMILY SSF46785 22 114 1.08E-27 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A0127_09050 57672ab2f7aca65d88e4ab7a35dc5567 346 Gene3D G3DSA:3.40.630.10 7 333 2.5E-130 T 23-10-2018 A0127_09050 57672ab2f7aca65d88e4ab7a35dc5567 346 PIRSF PIRSF001123 1 345 1.0E-101 T 23-10-2018 IPR008007 Peptidase M42 A0127_09050 57672ab2f7aca65d88e4ab7a35dc5567 346 Pfam PF05343 M42 glutamyl aminopeptidase 45 330 9.9E-97 T 23-10-2018 IPR008007 Peptidase M42 A0127_09050 57672ab2f7aca65d88e4ab7a35dc5567 346 SUPERFAMILY SSF53187 4 340 1.5E-61 T 23-10-2018 A0127_09050 57672ab2f7aca65d88e4ab7a35dc5567 346 Gene3D G3DSA:2.40.30.40 68 160 2.5E-130 T 23-10-2018 IPR023367 Peptidase M42, domain 2 A0127_09050 57672ab2f7aca65d88e4ab7a35dc5567 346 SUPERFAMILY SSF101821 68 176 1.68E-26 T 23-10-2018 A0127_09730 89cf9412ee8ea158bc7c4a8db563aa54 65 ProSitePatterns PS01168 Ribosomal protein S27e signature. 19 51 - T 23-10-2018 IPR000592 Ribosomal protein S27e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_09730 89cf9412ee8ea158bc7c4a8db563aa54 65 Pfam PF01667 Ribosomal protein S27 11 64 1.7E-26 T 23-10-2018 IPR000592 Ribosomal protein S27e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_09730 89cf9412ee8ea158bc7c4a8db563aa54 65 Hamap MF_00371 30S ribosomal protein S27e [rps27e]. 5 64 22.608 T 23-10-2018 IPR000592 Ribosomal protein S27e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_09730 89cf9412ee8ea158bc7c4a8db563aa54 65 SUPERFAMILY SSF57829 11 65 1.04E-19 T 23-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 A0127_09730 89cf9412ee8ea158bc7c4a8db563aa54 65 Gene3D G3DSA:2.20.25.100 11 65 3.9E-25 T 23-10-2018 IPR023407 Ribosomal protein S27e, zinc-binding domain superfamily A0127_07805 8b72d35d50a336444f44cc8363c61c4f 356 Gene3D G3DSA:1.25.40.10 45 111 2.4E-7 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A0127_07345 52bdceac2156665de1031156803b877c 90 Gene3D G3DSA:3.40.50.300 1 86 7.2E-20 T 23-10-2018 A0127_06185 2b596a7ce8bd707e861bd1f98302b40a 135 ProDom PD016056 UPF0216 PYRAB16100 PH0358 MTH949 MK1676 AF0460 PF0452 MJ1224 8 132 1.0E-43 T 23-10-2018 IPR002746 Uncharacterised protein family UPF0216 A0127_06185 2b596a7ce8bd707e861bd1f98302b40a 135 Pfam PF01886 Protein of unknown function DUF61 6 132 2.8E-35 T 23-10-2018 IPR002746 Uncharacterised protein family UPF0216 A0127_06185 2b596a7ce8bd707e861bd1f98302b40a 135 PIRSF PIRSF005264 1 135 1.6E-41 T 23-10-2018 IPR002746 Uncharacterised protein family UPF0216 A0127_06185 2b596a7ce8bd707e861bd1f98302b40a 135 Hamap MF_00585 UPF0216 protein . 4 135 26.193 T 23-10-2018 IPR002746 Uncharacterised protein family UPF0216 A0127_00910 684ad607b6a99a2f52df4225998e0726 475 SUPERFAMILY SSF101960 39 468 7.06E-128 T 23-10-2018 IPR037284 SUF system FeS cluster assembly, SufBD superfamily A0127_00910 684ad607b6a99a2f52df4225998e0726 475 TIGRFAM TIGR01980 sufB: FeS assembly protein SufB 30 464 2.6E-191 T 23-10-2018 IPR010231 SUF system FeS cluster assembly, SufB GO:0016226 A0127_00910 684ad607b6a99a2f52df4225998e0726 475 Pfam PF01458 Uncharacterized protein family (UPF0051) 219 444 2.6E-66 T 23-10-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 A0127_08745 642d3511cd452b4f499c82641c340c12 92 Pfam PF10437 Bacterial lipoate protein ligase C-terminus 7 64 8.8E-8 T 23-10-2018 IPR019491 Lipoate protein ligase, C-terminal KEGG: 00785+6.3.1.20 A0127_08745 642d3511cd452b4f499c82641c340c12 92 SUPERFAMILY SSF82649 4 86 2.14E-11 T 23-10-2018 A0127_08745 642d3511cd452b4f499c82641c340c12 92 Gene3D G3DSA:3.30.390.50 1 88 1.0E-26 T 23-10-2018 A0127_08610 cd34553f2604bc8af0de9bcf4fa1dc89 635 TIGRFAM TIGR00764 lon_rel: putative ATP-dependent protease 22 627 0.0 T 23-10-2018 IPR004663 Lon protease, archaeal GO:0004176|GO:0005524|GO:0030163 A0127_08610 cd34553f2604bc8af0de9bcf4fa1dc89 635 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 438 454 3.7E-29 T 23-10-2018 A0127_08610 cd34553f2604bc8af0de9bcf4fa1dc89 635 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 515 534 3.7E-29 T 23-10-2018 A0127_08610 cd34553f2604bc8af0de9bcf4fa1dc89 635 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 65 84 3.7E-29 T 23-10-2018 A0127_08610 cd34553f2604bc8af0de9bcf4fa1dc89 635 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 545 564 3.7E-29 T 23-10-2018 A0127_08610 cd34553f2604bc8af0de9bcf4fa1dc89 635 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 568 586 3.7E-29 T 23-10-2018 A0127_08610 cd34553f2604bc8af0de9bcf4fa1dc89 635 Pfam PF01078 Magnesium chelatase, subunit ChlI 39 91 1.9E-9 T 23-10-2018 IPR000523 Magnesium chelatase ChlI domain A0127_08610 cd34553f2604bc8af0de9bcf4fa1dc89 635 Gene3D G3DSA:3.40.50.300 162 318 4.9E-43 T 23-10-2018 A0127_08610 cd34553f2604bc8af0de9bcf4fa1dc89 635 Gene3D G3DSA:3.40.50.300 18 127 6.1E-31 T 23-10-2018 A0127_08610 cd34553f2604bc8af0de9bcf4fa1dc89 635 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 433 613 3.2E-37 T 23-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 A0127_08610 cd34553f2604bc8af0de9bcf4fa1dc89 635 SUPERFAMILY SSF54211 438 611 5.31E-45 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A0127_08610 cd34553f2604bc8af0de9bcf4fa1dc89 635 SUPERFAMILY SSF52540 34 412 2.43E-37 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_08610 cd34553f2604bc8af0de9bcf4fa1dc89 635 SMART SM00382 57 316 1.7E-5 T 23-10-2018 IPR003593 AAA+ ATPase domain A0127_08610 cd34553f2604bc8af0de9bcf4fa1dc89 635 Pfam PF13654 AAA domain 181 408 1.8E-22 T 23-10-2018 A0127_08610 cd34553f2604bc8af0de9bcf4fa1dc89 635 Gene3D G3DSA:3.30.230.10 430 634 2.5E-79 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A0127_08610 cd34553f2604bc8af0de9bcf4fa1dc89 635 Gene3D G3DSA:1.10.8.60 319 411 4.3E-44 T 23-10-2018 A0127_06105 4d4a8aed62cd2031de9e91fcb5dae1aa 652 SUPERFAMILY SSF74650 385 651 1.44E-100 T 23-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 A0127_06105 4d4a8aed62cd2031de9e91fcb5dae1aa 652 ProDom PD014405 HYDROLASE METABOLISM CARBOHYDRATE GLYCOSIDASE ALPHA-AMYLASE TRANSFERASE 4-ALPHA-GLUCANOTRANSFERASE GLYCOSYLTRANSFERASE FAMILY DIRECT 317 382 1.0E-30 T 23-10-2018 IPR015178 Alpha-amylase/4-alpha-glucanotransferase, central domain A0127_06105 4d4a8aed62cd2031de9e91fcb5dae1aa 652 Pfam PF09094 Domain of unknown function (DUF1925) 309 381 6.6E-37 T 23-10-2018 IPR015178 Alpha-amylase/4-alpha-glucanotransferase, central domain A0127_06105 4d4a8aed62cd2031de9e91fcb5dae1aa 652 Pfam PF03065 Glycosyl hydrolase family 57 5 288 1.7E-65 T 23-10-2018 IPR004300 Glycoside hydrolase family 57, N-terminal domain GO:0003824|GO:0005975 A0127_06105 4d4a8aed62cd2031de9e91fcb5dae1aa 652 Gene3D G3DSA:2.70.98.10 386 652 1.6E-89 T 23-10-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 A0127_06105 4d4a8aed62cd2031de9e91fcb5dae1aa 652 SUPERFAMILY SSF88713 3 307 6.3E-67 T 23-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 A0127_06105 4d4a8aed62cd2031de9e91fcb5dae1aa 652 Gene3D G3DSA:3.20.110.20 1 379 1.8E-175 T 23-10-2018 A0127_06105 4d4a8aed62cd2031de9e91fcb5dae1aa 652 Pfam PF09095 Domain of unknown function (DUF1926) 390 647 1.1E-80 T 23-10-2018 IPR015179 Alpha-amylase/4-alpha-glucanotransferase, C-terminal GO:0003824|GO:0005975|GO:0030246 A0127_06105 4d4a8aed62cd2031de9e91fcb5dae1aa 652 SUPERFAMILY SSF88688 309 381 1.31E-36 T 23-10-2018 IPR028995 Glycoside hydrolase families 57/38, central domain superfamily A0127_04845 2a1c95d5f81dafee34455c8e26e85fe8 276 Gene3D G3DSA:3.40.50.300 2 241 2.5E-45 T 23-10-2018 A0127_04845 2a1c95d5f81dafee34455c8e26e85fe8 276 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 4 221 3.7E-17 T 23-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain A0127_04845 2a1c95d5f81dafee34455c8e26e85fe8 276 SUPERFAMILY SSF52540 3 241 5.04E-43 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_02970 1e6b6f25825bdf953c2267500de1eed4 143 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 3 143 25.508 T 23-10-2018 IPR033747 Class I PurE A0127_02970 1e6b6f25825bdf953c2267500de1eed4 143 Pfam PF00731 AIR carboxylase 2 141 1.9E-55 T 23-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 A0127_02970 1e6b6f25825bdf953c2267500de1eed4 143 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 3 141 3.9E-54 T 23-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 A0127_02970 1e6b6f25825bdf953c2267500de1eed4 143 SUPERFAMILY SSF52255 1 141 1.83E-52 T 23-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 A0127_02970 1e6b6f25825bdf953c2267500de1eed4 143 PIRSF PIRSF001338 1 143 1.4E-57 T 23-10-2018 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 A0127_02970 1e6b6f25825bdf953c2267500de1eed4 143 SMART SM01001 1 142 7.8E-71 T 23-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 A0127_02970 1e6b6f25825bdf953c2267500de1eed4 143 Gene3D G3DSA:3.40.50.7700 2 143 3.4E-60 T 23-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 A0127_10085 01a521e68fdeb1dea6cde8952aac8585 101 SUPERFAMILY SSF52833 12 99 2.94E-20 T 23-10-2018 IPR036249 Thioredoxin-like superfamily A0127_10085 01a521e68fdeb1dea6cde8952aac8585 101 ProSitePatterns PS00194 Thioredoxin family active site. 17 35 - T 23-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 A0127_10085 01a521e68fdeb1dea6cde8952aac8585 101 Pfam PF00085 Thioredoxin 12 95 1.0E-13 T 23-10-2018 IPR013766 Thioredoxin domain GO:0045454 A0127_10085 01a521e68fdeb1dea6cde8952aac8585 101 Gene3D G3DSA:3.40.30.10 3 100 2.1E-17 T 23-10-2018 A0127_02490 3082d033ca8052477a8065a1652d0c28 284 Gene3D G3DSA:3.20.20.60 2 273 8.8E-110 T 23-10-2018 A0127_02490 3082d033ca8052477a8065a1652d0c28 284 Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. 4 262 40.94 T 23-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 A0127_02490 3082d033ca8052477a8065a1652d0c28 284 SUPERFAMILY SSF51621 4 262 8.24E-102 T 23-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 A0127_02490 3082d033ca8052477a8065a1652d0c28 284 TIGRFAM TIGR00222 panB: 3-methyl-2-oxobutanoate hydroxymethyltransferase 9 262 6.5E-89 T 23-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 A0127_02490 3082d033ca8052477a8065a1652d0c28 284 PIRSF PIRSF000388 1 265 1.3E-103 T 23-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 A0127_02490 3082d033ca8052477a8065a1652d0c28 284 Pfam PF02548 Ketopantoate hydroxymethyltransferase 4 257 7.0E-107 T 23-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 A0127_09695 8debc689c13f58740346233c8a41d35f 271 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A0127_09695 8debc689c13f58740346233c8a41d35f 271 SUPERFAMILY SSF52540 5 230 8.45E-61 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_09695 8debc689c13f58740346233c8a41d35f 271 SMART SM00382 29 214 2.6E-11 T 23-10-2018 IPR003593 AAA+ ATPase domain A0127_09695 8debc689c13f58740346233c8a41d35f 271 Pfam PF00005 ABC transporter 20 166 1.5E-31 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A0127_09695 8debc689c13f58740346233c8a41d35f 271 Gene3D G3DSA:3.40.50.300 4 267 2.6E-72 T 23-10-2018 A0127_00550 5ac897c78f007a1a65aa4348b7826701 629 Gene3D G3DSA:3.30.1360.30 274 404 2.4E-53 T 23-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 A0127_00550 5ac897c78f007a1a65aa4348b7826701 629 Pfam PF02938 GAD domain 301 390 4.2E-17 T 23-10-2018 IPR029351 GAD domain Reactome: R-HSA-379726 A0127_00550 5ac897c78f007a1a65aa4348b7826701 629 TIGRFAM TIGR00134 gatE_arch: glutamyl-tRNA(Gln) amidotransferase, subunit E 5 627 2.5E-239 T 23-10-2018 IPR004414 Glutamyl-tRNA(Gln) amidotransferase subunit E GO:0016884 A0127_00550 5ac897c78f007a1a65aa4348b7826701 629 SMART SM00845 484 624 2.3E-36 T 23-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 A0127_00550 5ac897c78f007a1a65aa4348b7826701 629 SUPERFAMILY SSF55261 279 404 4.25E-46 T 23-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 A0127_00550 5ac897c78f007a1a65aa4348b7826701 629 SUPERFAMILY SSF55931 4 453 1.11E-99 T 23-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 A0127_00550 5ac897c78f007a1a65aa4348b7826701 629 ProDom PD609240 SUBUNIT E AMIDOTRANSFERASE 6.3.5.- LIGASE GLUTAMYL-TRNAGLN GLU-ADT BIOSYNTHESIS TRANSFERASE B 282 406 1.0E-60 T 23-10-2018 A0127_00550 5ac897c78f007a1a65aa4348b7826701 629 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 177 191 - T 23-10-2018 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 A0127_00550 5ac897c78f007a1a65aa4348b7826701 629 Gene3D G3DSA:1.10.150.380 453 545 1.3E-24 T 23-10-2018 A0127_00550 5ac897c78f007a1a65aa4348b7826701 629 Pfam PF02934 GatB/GatE catalytic domain 13 443 1.6E-64 T 23-10-2018 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 A0127_00550 5ac897c78f007a1a65aa4348b7826701 629 Hamap MF_00588 Glutamyl-tRNA(Gln) amidotransferase subunit E [gatE]. 1 629 341.761 T 23-10-2018 IPR004414 Glutamyl-tRNA(Gln) amidotransferase subunit E GO:0016884 A0127_00550 5ac897c78f007a1a65aa4348b7826701 629 SUPERFAMILY SSF89095 482 624 7.85E-28 T 23-10-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-like GO:0016884 A0127_00550 5ac897c78f007a1a65aa4348b7826701 629 Gene3D G3DSA:1.10.10.410 566 624 2.6E-13 T 23-10-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal A0127_00550 5ac897c78f007a1a65aa4348b7826701 629 Pfam PF02637 GatB domain 485 624 2.1E-28 T 23-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 A0127_08150 8ced1da8b783a379628eb51695e61420 232 SUPERFAMILY SSF51695 4 224 9.94E-30 T 23-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 A0127_08150 8ced1da8b783a379628eb51695e61420 232 Gene3D G3DSA:3.20.20.190 1 231 1.6E-32 T 23-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 A0127_08150 8ced1da8b783a379628eb51695e61420 232 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 8 73 1.7E-11 T 23-10-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 A0127_09970 f2e68a7140415a0d1b9ed16d5cd75651 741 SUPERFAMILY SSF47323 398 563 1.7E-46 T 23-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A0127_09970 f2e68a7140415a0d1b9ed16d5cd75651 741 Pfam PF08264 Anticodon-binding domain of tRNA 430 523 1.0E-13 T 23-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 A0127_09970 f2e68a7140415a0d1b9ed16d5cd75651 741 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 11 22 - T 23-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A0127_09970 f2e68a7140415a0d1b9ed16d5cd75651 741 SUPERFAMILY SSF50249 640 740 1.15E-37 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A0127_09970 f2e68a7140415a0d1b9ed16d5cd75651 741 Pfam PF09334 tRNA synthetases class I (M) 4 409 4.0E-160 T 23-10-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 A0127_09970 f2e68a7140415a0d1b9ed16d5cd75651 741 TIGRFAM TIGR00399 metG_C_term: methionine--tRNA ligase, beta subunit 617 741 5.1E-39 T 23-10-2018 IPR004495 Methionyl-tRNA synthetase, beta subunit, C-terminal GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A0127_09970 f2e68a7140415a0d1b9ed16d5cd75651 741 Gene3D G3DSA:2.170.220.10 98 252 6.3E-144 T 23-10-2018 A0127_09970 f2e68a7140415a0d1b9ed16d5cd75651 741 SUPERFAMILY SSF57770 139 173 1.02E-10 T 23-10-2018 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A0127_09970 f2e68a7140415a0d1b9ed16d5cd75651 741 Gene3D G3DSA:1.10.730.10 341 582 2.4E-106 T 23-10-2018 A0127_09970 f2e68a7140415a0d1b9ed16d5cd75651 741 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 5 549 2.8E-178 T 23-10-2018 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A0127_09970 f2e68a7140415a0d1b9ed16d5cd75651 741 Gene3D G3DSA:1.10.730.10 398 548 2.4E-106 T 23-10-2018 A0127_09970 f2e68a7140415a0d1b9ed16d5cd75651 741 Gene3D G3DSA:3.40.50.620 5 316 6.3E-144 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A0127_09970 f2e68a7140415a0d1b9ed16d5cd75651 741 SUPERFAMILY SSF52374 3 394 2.11E-106 T 23-10-2018 A0127_09970 f2e68a7140415a0d1b9ed16d5cd75651 741 Gene3D G3DSA:2.40.50.140 635 741 1.4E-44 T 23-10-2018 A0127_09970 f2e68a7140415a0d1b9ed16d5cd75651 741 PRINTS PR01041 Methionyl-tRNA synthetase signature 6 19 1.1E-32 T 23-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A0127_09970 f2e68a7140415a0d1b9ed16d5cd75651 741 PRINTS PR01041 Methionyl-tRNA synthetase signature 87 98 1.1E-32 T 23-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A0127_09970 f2e68a7140415a0d1b9ed16d5cd75651 741 PRINTS PR01041 Methionyl-tRNA synthetase signature 396 407 1.1E-32 T 23-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A0127_09970 f2e68a7140415a0d1b9ed16d5cd75651 741 PRINTS PR01041 Methionyl-tRNA synthetase signature 294 309 1.1E-32 T 23-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A0127_09970 f2e68a7140415a0d1b9ed16d5cd75651 741 PRINTS PR01041 Methionyl-tRNA synthetase signature 252 263 1.1E-32 T 23-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A0127_09970 f2e68a7140415a0d1b9ed16d5cd75651 741 PRINTS PR01041 Methionyl-tRNA synthetase signature 39 53 1.1E-32 T 23-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 A0127_09970 f2e68a7140415a0d1b9ed16d5cd75651 741 Hamap MF_00098 Methionine--tRNA ligase [metG]. 2 560 42.962 T 23-10-2018 IPR023458 Methionine-tRNA ligase, type 1 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A0127_09970 f2e68a7140415a0d1b9ed16d5cd75651 741 Pfam PF01588 Putative tRNA binding domain 647 738 1.3E-32 T 23-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 A0127_04365 bcfb123de4a45150ee469031f0f255a7 152 SUPERFAMILY SSF54893 3 99 8.5E-33 T 23-10-2018 IPR036793 Aspartate carbamoyltransferase regulatory subunit, N-terminal domain superfamily A0127_04365 bcfb123de4a45150ee469031f0f255a7 152 Pfam PF01948 Aspartate carbamoyltransferase regulatory chain, allosteric domain 5 97 9.2E-33 T 23-10-2018 IPR020545 Aspartate carbamoyltransferase regulatory subunit, N-terminal A0127_04365 bcfb123de4a45150ee469031f0f255a7 152 Gene3D G3DSA:2.30.30.20 99 149 9.9E-24 T 23-10-2018 A0127_04365 bcfb123de4a45150ee469031f0f255a7 152 Gene3D G3DSA:3.30.70.140 1 98 1.2E-36 T 23-10-2018 IPR036793 Aspartate carbamoyltransferase regulatory subunit, N-terminal domain superfamily A0127_04365 bcfb123de4a45150ee469031f0f255a7 152 Hamap MF_00002 Aspartate carbamoyltransferase regulatory chain [pyrI]. 2 150 34.212 T 23-10-2018 IPR002801 Aspartate transcarbamylase regulatory subunit GO:0006207|GO:0009347 A0127_04365 bcfb123de4a45150ee469031f0f255a7 152 TIGRFAM TIGR00240 ATCase_reg: aspartate carbamoyltransferase, regulatory subunit 3 148 4.2E-61 T 23-10-2018 IPR002801 Aspartate transcarbamylase regulatory subunit GO:0006207|GO:0009347 A0127_04365 bcfb123de4a45150ee469031f0f255a7 152 Pfam PF02748 Aspartate carbamoyltransferase regulatory chain, metal binding domain 101 148 1.0E-21 T 23-10-2018 IPR020542 Aspartate carbamoyltransferase regulatory subunit, C-terminal A0127_04365 bcfb123de4a45150ee469031f0f255a7 152 SUPERFAMILY SSF57825 101 148 4.19E-17 T 23-10-2018 IPR036792 Aspartate carbamoyltransferase regulatory subunit, C-terminal domain superfamily A0127_04365 bcfb123de4a45150ee469031f0f255a7 152 ProDom PD006194 REGULATORY ASPARTATE CARBAMOYLTRANSFERASE CHAIN METAL-BINDING ZINC PYRIMIDINE BIOSYNTHESIS SUBUNIT TRANSFERASE 7 98 1.0E-44 T 23-10-2018 IPR020545 Aspartate carbamoyltransferase regulatory subunit, N-terminal A0127_06460 d0a15b961fa8a24d71040987067c358b 268 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 7 236 1.4E-46 T 23-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA A0127_06460 d0a15b961fa8a24d71040987067c358b 268 Gene3D G3DSA:3.40.50.1000 72 188 1.3E-91 T 23-10-2018 IPR023214 HAD superfamily A0127_06460 d0a15b961fa8a24d71040987067c358b 268 PIRSF PIRSF000915 5 266 7.8E-63 T 23-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA A0127_06460 d0a15b961fa8a24d71040987067c358b 268 SUPERFAMILY SSF56784 6 260 6.08E-64 T 23-10-2018 IPR036412 HAD-like superfamily A0127_06460 d0a15b961fa8a24d71040987067c358b 268 Pfam PF13344 Haloacid dehalogenase-like hydrolase 7 106 4.2E-26 T 23-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA A0127_06460 d0a15b961fa8a24d71040987067c358b 268 Gene3D G3DSA:3.40.50.1000 8 254 1.3E-91 T 23-10-2018 IPR023214 HAD superfamily A0127_06460 d0a15b961fa8a24d71040987067c358b 268 Pfam PF13242 HAD-hyrolase-like 188 260 2.3E-18 T 23-10-2018 A0127_02655 fc9452059c51378d9fef3e33c9ef7cee 218 SUPERFAMILY SSF89550 6 214 4.84E-41 T 23-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 A0127_02655 fc9452059c51378d9fef3e33c9ef7cee 218 Pfam PF02811 PHP domain 7 88 1.3E-8 T 23-10-2018 IPR004013 PHP domain GO:0003824 A0127_02655 fc9452059c51378d9fef3e33c9ef7cee 218 SMART SM00481 6 78 1.7E-13 T 23-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal A0127_02655 fc9452059c51378d9fef3e33c9ef7cee 218 Gene3D G3DSA:3.20.20.140 3 217 8.5E-49 T 23-10-2018 A0127_07355 ba32dd6744cc69dfb3da314b9a74809c 490 Gene3D G3DSA:1.20.1480.50 35 138 6.0E-7 T 23-10-2018 A0127_07355 ba32dd6744cc69dfb3da314b9a74809c 490 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 270 401 1.6E-35 T 23-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 A0127_07355 ba32dd6744cc69dfb3da314b9a74809c 490 Gene3D G3DSA:1.10.287.950 180 485 9.4E-63 T 23-10-2018 A0127_07355 ba32dd6744cc69dfb3da314b9a74809c 490 SMART SM00283 210 485 6.1E-55 T 23-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 A0127_07355 ba32dd6744cc69dfb3da314b9a74809c 490 SUPERFAMILY SSF58104 149 482 2.35E-59 T 23-10-2018 A0127_01715 9e5c9d5fc522d56924f8ea19cacbd46b 902 SUPERFAMILY SSF52540 57 378 5.87E-49 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_01715 9e5c9d5fc522d56924f8ea19cacbd46b 902 Gene3D G3DSA:3.40.50.300 253 405 9.6E-23 T 23-10-2018 A0127_01715 9e5c9d5fc522d56924f8ea19cacbd46b 902 SMART SM00487 44 251 3.5E-30 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A0127_01715 9e5c9d5fc522d56924f8ea19cacbd46b 902 Pfam PF00270 DEAD/DEAH box helicase 50 227 1.4E-23 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A0127_01715 9e5c9d5fc522d56924f8ea19cacbd46b 902 Pfam PF00271 Helicase conserved C-terminal domain 271 375 6.7E-18 T 23-10-2018 IPR001650 Helicase, C-terminal A0127_01715 9e5c9d5fc522d56924f8ea19cacbd46b 902 Gene3D G3DSA:3.40.50.300 30 241 1.1E-40 T 23-10-2018 A0127_01715 9e5c9d5fc522d56924f8ea19cacbd46b 902 SMART SM00490 293 376 6.9E-19 T 23-10-2018 IPR001650 Helicase, C-terminal A0127_01715 9e5c9d5fc522d56924f8ea19cacbd46b 902 Pfam PF09369 Domain of unknown function (DUF1998) 782 864 3.7E-15 T 23-10-2018 IPR018973 DEAD/DEAH-box helicase, putative A0127_08275 a25a4dc35d465c091d6c207621e73991 97 SUPERFAMILY SSF46785 6 88 6.82E-23 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A0127_08275 a25a4dc35d465c091d6c207621e73991 97 Pfam PF01022 Bacterial regulatory protein, arsR family 17 63 3.1E-14 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A0127_08275 a25a4dc35d465c091d6c207621e73991 97 SMART SM00418 10 91 2.1E-14 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A0127_08275 a25a4dc35d465c091d6c207621e73991 97 Gene3D G3DSA:1.10.10.10 5 95 1.3E-22 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A0127_01030 b94ec3c7b63b13b02e56a65fc2e87163 224 SUPERFAMILY SSF52540 2 212 6.69E-39 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_01030 b94ec3c7b63b13b02e56a65fc2e87163 224 Gene3D G3DSA:3.40.50.300 1 219 6.3E-77 T 23-10-2018 A0127_01030 b94ec3c7b63b13b02e56a65fc2e87163 224 TIGRFAM TIGR01351 adk: adenylate kinase 3 210 1.9E-74 T 23-10-2018 IPR006259 Adenylate kinase subfamily GO:0004017|GO:0005524|GO:0016776 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 A0127_01030 b94ec3c7b63b13b02e56a65fc2e87163 224 ProSitePatterns PS00113 Adenylate kinase signature. 79 90 - T 23-10-2018 IPR033690 Adenylate kinase, conserved site KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A0127_01030 b94ec3c7b63b13b02e56a65fc2e87163 224 PRINTS PR00094 Adenylate kinase signature 158 173 1.3E-26 T 23-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A0127_01030 b94ec3c7b63b13b02e56a65fc2e87163 224 PRINTS PR00094 Adenylate kinase signature 4 17 1.3E-26 T 23-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A0127_01030 b94ec3c7b63b13b02e56a65fc2e87163 224 PRINTS PR00094 Adenylate kinase signature 175 189 1.3E-26 T 23-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A0127_01030 b94ec3c7b63b13b02e56a65fc2e87163 224 PRINTS PR00094 Adenylate kinase signature 32 46 1.3E-26 T 23-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A0127_01030 b94ec3c7b63b13b02e56a65fc2e87163 224 PRINTS PR00094 Adenylate kinase signature 79 95 1.3E-26 T 23-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A0127_01030 b94ec3c7b63b13b02e56a65fc2e87163 224 Hamap MF_00235 Adenylate kinase [adk]. 1 211 46.026 T 23-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A0127_01030 b94ec3c7b63b13b02e56a65fc2e87163 224 Pfam PF05191 Adenylate kinase, active site lid 125 160 4.3E-20 T 23-10-2018 IPR007862 Adenylate kinase, active site lid domain GO:0004017 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 A0127_01030 b94ec3c7b63b13b02e56a65fc2e87163 224 Pfam PF00406 Adenylate kinase 6 188 1.5E-41 T 23-10-2018 A0127_08115 fcb8bb91f1ed00bfcb5674dfe61a7cee 830 Pfam PF00343 Carbohydrate phosphorylase 273 339 3.3E-5 T 23-10-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 A0127_08115 fcb8bb91f1ed00bfcb5674dfe61a7cee 830 Pfam PF00343 Carbohydrate phosphorylase 127 176 2.1E-5 T 23-10-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 A0127_08115 fcb8bb91f1ed00bfcb5674dfe61a7cee 830 Pfam PF00343 Carbohydrate phosphorylase 350 612 4.2E-21 T 23-10-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 A0127_08115 fcb8bb91f1ed00bfcb5674dfe61a7cee 830 Gene3D G3DSA:3.40.50.2000 117 186 2.2E-11 T 23-10-2018 A0127_08115 fcb8bb91f1ed00bfcb5674dfe61a7cee 830 ProSitePatterns PS00102 Phosphorylase pyridoxal-phosphate attachment site. 586 598 - T 23-10-2018 IPR035090 Phosphorylase pyridoxal-phosphate attachment site KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 A0127_08115 fcb8bb91f1ed00bfcb5674dfe61a7cee 830 PIRSF PIRSF000460 1 768 1.3E-275 T 23-10-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 A0127_08115 fcb8bb91f1ed00bfcb5674dfe61a7cee 830 Pfam PF11897 Protein of unknown function (DUF3417) 16 123 8.0E-31 T 23-10-2018 IPR024517 Glycogen phosphorylase, domain of unknown function DUF3417 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238 A0127_08115 fcb8bb91f1ed00bfcb5674dfe61a7cee 830 Gene3D G3DSA:3.40.50.2000 269 406 5.0E-8 T 23-10-2018 A0127_08115 fcb8bb91f1ed00bfcb5674dfe61a7cee 830 SUPERFAMILY SSF53756 17 726 2.04E-207 T 23-10-2018 A0127_08115 fcb8bb91f1ed00bfcb5674dfe61a7cee 830 Gene3D G3DSA:3.40.50.2000 407 728 1.2E-43 T 23-10-2018 A0127_08115 fcb8bb91f1ed00bfcb5674dfe61a7cee 830 TIGRFAM TIGR02094 more_P_ylases: alpha-glucan phosphorylases 110 692 1.2E-256 T 23-10-2018 IPR011834 Alpha-glucan phosphorylase GO:0004645|GO:0005975|GO:0030170 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238 A0127_09590 da85d01bcbfe4f4841665902e6f37a03 162 Pfam PF00582 Universal stress protein family 1 152 1.8E-25 T 23-10-2018 IPR006016 UspA A0127_09590 da85d01bcbfe4f4841665902e6f37a03 162 PRINTS PR01438 Universal stress protein signature 2 20 4.2E-15 T 23-10-2018 IPR006015 Universal stress protein A A0127_09590 da85d01bcbfe4f4841665902e6f37a03 162 PRINTS PR01438 Universal stress protein signature 112 124 4.2E-15 T 23-10-2018 IPR006015 Universal stress protein A A0127_09590 da85d01bcbfe4f4841665902e6f37a03 162 PRINTS PR01438 Universal stress protein signature 130 152 4.2E-15 T 23-10-2018 IPR006015 Universal stress protein A A0127_09590 da85d01bcbfe4f4841665902e6f37a03 162 Gene3D G3DSA:3.40.50.620 1 157 5.6E-51 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A0127_09590 da85d01bcbfe4f4841665902e6f37a03 162 SUPERFAMILY SSF52402 2 155 2.26E-24 T 23-10-2018 A0127_00785 7fa076a235098fe8bf2c6a4dfaa28a1b 161 Pfam PF03975 CheD chemotactic sensory transduction 46 150 1.8E-36 T 23-10-2018 IPR005659 Chemoreceptor glutamine deamidase CheD GO:0006935|GO:0050568 A0127_00785 7fa076a235098fe8bf2c6a4dfaa28a1b 161 Gene3D G3DSA:3.30.1330.200 1 159 4.3E-55 T 23-10-2018 IPR038592 CheD-like superfamily A0127_00785 7fa076a235098fe8bf2c6a4dfaa28a1b 161 Hamap MF_01440 Chemoreceptor glutamine deamidase CheD [cheD]. 1 154 27.461 T 23-10-2018 IPR005659 Chemoreceptor glutamine deamidase CheD GO:0006935|GO:0050568 A0127_00785 7fa076a235098fe8bf2c6a4dfaa28a1b 161 SUPERFAMILY SSF64438 2 154 1.01E-49 T 23-10-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic A0127_00520 b3bd10ea7e69ef2da5c52046b53f3438 501 Gene3D G3DSA:1.10.10.2310 20 221 6.2E-13 T 23-10-2018 A0127_00520 b3bd10ea7e69ef2da5c52046b53f3438 501 Hamap MF_00282 Phenylalanine--tRNA ligase alpha subunit [pheS]. 2 498 38.009 T 23-10-2018 IPR022917 Phenylalanine-tRNA ligase alpha subunit, bacterial/archaeal GO:0004826 KEGG: 00970+6.1.1.20 A0127_00520 b3bd10ea7e69ef2da5c52046b53f3438 501 Gene3D G3DSA:3.30.930.10 239 501 2.8E-76 T 23-10-2018 A0127_00520 b3bd10ea7e69ef2da5c52046b53f3438 501 Gene3D G3DSA:1.10.10.2330 74 137 6.2E-13 T 23-10-2018 A0127_00520 b3bd10ea7e69ef2da5c52046b53f3438 501 Pfam PF01409 tRNA synthetases class II core domain (F) 224 496 5.2E-83 T 23-10-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 A0127_00520 b3bd10ea7e69ef2da5c52046b53f3438 501 SUPERFAMILY SSF55681 224 497 1.08E-60 T 23-10-2018 A0127_00520 b3bd10ea7e69ef2da5c52046b53f3438 501 Gene3D G3DSA:1.10.10.2320 61 173 6.2E-13 T 23-10-2018 A0127_00520 b3bd10ea7e69ef2da5c52046b53f3438 501 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 187 497 1.0E-95 T 23-10-2018 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 A0127_00520 b3bd10ea7e69ef2da5c52046b53f3438 501 SUPERFAMILY SSF46785 3 110 1.44E-5 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A0127_04730 8058cb7786bd3d5965304caba3370de0 375 PIRSF PIRSF015647 5 375 3.4E-192 T 23-10-2018 IPR002803 Fructose-1,6-bisphosphatase, class V KEGG: 00010+4.1.2.13+3.1.3.11|KEGG: 00030+4.1.2.13+3.1.3.11|KEGG: 00051+4.1.2.13+3.1.3.11|KEGG: 00680+4.1.2.13+3.1.3.11|KEGG: 00710+4.1.2.13+3.1.3.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 A0127_04730 8058cb7786bd3d5965304caba3370de0 375 ProDom PD014260 DIHYDROOROTATE DEHYDROGENASE THERMOPHILE-SPECIFIC TA1428 ST0318 BLL2851 16-BISPHOSPHATASE APE1109 PF0613 MJ0299 6 371 0.0 T 23-10-2018 IPR002803 Fructose-1,6-bisphosphatase, class V KEGG: 00010+4.1.2.13+3.1.3.11|KEGG: 00030+4.1.2.13+3.1.3.11|KEGG: 00051+4.1.2.13+3.1.3.11|KEGG: 00680+4.1.2.13+3.1.3.11|KEGG: 00710+4.1.2.13+3.1.3.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 A0127_04730 8058cb7786bd3d5965304caba3370de0 375 SUPERFAMILY SSF111249 6 372 7.72E-179 T 23-10-2018 IPR036076 Fructose-1,6-bisphosphatase, class V superfamily KEGG: 00010+3.1.3.11+4.1.2.13|KEGG: 00030+3.1.3.11+4.1.2.13|KEGG: 00051+3.1.3.11+4.1.2.13|KEGG: 00680+3.1.3.11+4.1.2.13|KEGG: 00710+3.1.3.11+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 A0127_04730 8058cb7786bd3d5965304caba3370de0 375 Pfam PF01950 Fructose-1,6-bisphosphatase 6 372 1.3E-187 T 23-10-2018 IPR002803 Fructose-1,6-bisphosphatase, class V KEGG: 00010+4.1.2.13+3.1.3.11|KEGG: 00030+4.1.2.13+3.1.3.11|KEGG: 00051+4.1.2.13+3.1.3.11|KEGG: 00680+4.1.2.13+3.1.3.11|KEGG: 00710+4.1.2.13+3.1.3.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 A0127_04730 8058cb7786bd3d5965304caba3370de0 375 Hamap MF_02067 Fructose-1,6-bisphosphate aldolase/phosphatase [fbp]. 5 372 62.329 T 23-10-2018 IPR002803 Fructose-1,6-bisphosphatase, class V KEGG: 00010+4.1.2.13+3.1.3.11|KEGG: 00030+4.1.2.13+3.1.3.11|KEGG: 00051+4.1.2.13+3.1.3.11|KEGG: 00680+4.1.2.13+3.1.3.11|KEGG: 00710+4.1.2.13+3.1.3.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 A0127_08350 ddd20c2072f1c6b3c1bdb11f40b96b20 482 Gene3D G3DSA:1.10.287.70 388 482 9.8E-14 T 23-10-2018 A0127_08350 ddd20c2072f1c6b3c1bdb11f40b96b20 482 SUPERFAMILY SSF81324 399 481 6.54E-17 T 23-10-2018 A0127_08350 ddd20c2072f1c6b3c1bdb11f40b96b20 482 Pfam PF07885 Ion channel 412 481 8.6E-14 T 23-10-2018 IPR013099 Potassium channel domain A0127_03360 64e000a61aad8dd67a929ff6e22bc3d4 647 SUPERFAMILY SSF52922 248 355 9.77E-8 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A0127_03360 64e000a61aad8dd67a929ff6e22bc3d4 647 SUPERFAMILY SSF52518 14 250 2.77E-57 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold A0127_03360 64e000a61aad8dd67a929ff6e22bc3d4 647 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 625 636 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A0127_03360 64e000a61aad8dd67a929ff6e22bc3d4 647 PIRSF PIRSF006439 5 647 6.2E-262 T 23-10-2018 IPR017721 Indolepyruvate ferredoxin oxidoreductase, alpha subunit GO:0043805|GO:0055114 A0127_03360 64e000a61aad8dd67a929ff6e22bc3d4 647 Gene3D G3DSA:3.40.50.970 388 577 1.5E-22 T 23-10-2018 A0127_03360 64e000a61aad8dd67a929ff6e22bc3d4 647 TIGRFAM TIGR03336 IOR_alpha: indolepyruvate ferredoxin oxidoreductase, alpha subunit 16 640 1.6E-273 T 23-10-2018 IPR017721 Indolepyruvate ferredoxin oxidoreductase, alpha subunit GO:0043805|GO:0055114 A0127_03360 64e000a61aad8dd67a929ff6e22bc3d4 647 Gene3D G3DSA:3.30.70.20 578 647 3.5E-11 T 23-10-2018 A0127_03360 64e000a61aad8dd67a929ff6e22bc3d4 647 SUPERFAMILY SSF54862 584 640 6.04E-14 T 23-10-2018 A0127_03360 64e000a61aad8dd67a929ff6e22bc3d4 647 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 410 564 1.4E-29 T 23-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 A0127_03360 64e000a61aad8dd67a929ff6e22bc3d4 647 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 28 207 6.6E-15 T 23-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 A0127_03360 64e000a61aad8dd67a929ff6e22bc3d4 647 SUPERFAMILY SSF52518 380 601 1.62E-31 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold A0127_03360 64e000a61aad8dd67a929ff6e22bc3d4 647 Pfam PF00037 4Fe-4S binding domain 619 640 2.5E-7 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A0127_03360 64e000a61aad8dd67a929ff6e22bc3d4 647 Gene3D G3DSA:3.40.50.970 7 196 1.0E-53 T 23-10-2018 A0127_00285 7015b0527f977bad488158cc04293af4 133 Pfam PF01850 PIN domain 2 124 6.4E-11 T 23-10-2018 IPR002716 PIN domain A0127_00285 7015b0527f977bad488158cc04293af4 133 Gene3D G3DSA:3.40.50.1010 1 128 3.3E-25 T 23-10-2018 A0127_00285 7015b0527f977bad488158cc04293af4 133 SUPERFAMILY SSF88723 2 131 3.92E-16 T 23-10-2018 IPR029060 PIN-like domain superfamily A0127_05035 259f4c8f9f46dfcc04dff57e9d63f30d 378 Pfam PF01497 Periplasmic binding protein 56 299 1.1E-24 T 23-10-2018 IPR002491 ABC transporter periplasmic binding domain A0127_05035 259f4c8f9f46dfcc04dff57e9d63f30d 378 SUPERFAMILY SSF53807 39 354 8.63E-57 T 23-10-2018 A0127_05035 259f4c8f9f46dfcc04dff57e9d63f30d 378 Gene3D G3DSA:3.40.50.1980 28 177 1.3E-52 T 23-10-2018 A0127_05035 259f4c8f9f46dfcc04dff57e9d63f30d 378 Gene3D G3DSA:3.40.50.1980 179 374 1.7E-79 T 23-10-2018 A0127_00025 a8d4fd46c6709e9e7f6a81dd2239ff50 67 Pfam PF01954 Protein of unknown function DUF104 1 55 2.1E-17 T 23-10-2018 IPR008203 Uncharacterised protein family UPF0165 A0127_00025 a8d4fd46c6709e9e7f6a81dd2239ff50 67 SUPERFAMILY SSF141694 1 40 2.43E-11 T 23-10-2018 A0127_00025 a8d4fd46c6709e9e7f6a81dd2239ff50 67 Gene3D G3DSA:4.10.1150.10 1 64 3.0E-10 T 23-10-2018 IPR024069 AF2212-like domain superfamily A0127_10310 dbb833d9dab91fe6fb5b27a647b786ef 190 SUPERFAMILY SSF52218 1 168 4.46E-33 T 23-10-2018 IPR029039 Flavoprotein-like superfamily A0127_10310 dbb833d9dab91fe6fb5b27a647b786ef 190 Pfam PF03358 NADPH-dependent FMN reductase 1 135 2.4E-26 T 23-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 A0127_10310 dbb833d9dab91fe6fb5b27a647b786ef 190 Gene3D G3DSA:3.40.50.360 1 190 3.2E-38 T 23-10-2018 IPR029039 Flavoprotein-like superfamily A0127_08725 2ec5da23480e952be75c1a3ff8d808b7 296 PIRSF PIRSF001365 1 294 1.5E-79 T 23-10-2018 IPR002220 DapA-like GO:0016829 A0127_08725 2ec5da23480e952be75c1a3ff8d808b7 296 Pfam PF00701 Dihydrodipicolinate synthetase family 2 289 4.2E-61 T 23-10-2018 IPR002220 DapA-like GO:0016829 A0127_08725 2ec5da23480e952be75c1a3ff8d808b7 296 SMART SM01130 1 292 1.8E-90 T 23-10-2018 IPR002220 DapA-like GO:0016829 A0127_08725 2ec5da23480e952be75c1a3ff8d808b7 296 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 131 161 - T 23-10-2018 IPR020625 Schiff base-forming aldolase, active site GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 A0127_08725 2ec5da23480e952be75c1a3ff8d808b7 296 Gene3D G3DSA:3.20.20.70 1 292 1.6E-86 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A0127_08725 2ec5da23480e952be75c1a3ff8d808b7 296 PRINTS PR00146 Dihydrodipicolinate synthase signature 34 55 2.2E-14 T 23-10-2018 IPR002220 DapA-like GO:0016829 A0127_08725 2ec5da23480e952be75c1a3ff8d808b7 296 PRINTS PR00146 Dihydrodipicolinate synthase signature 69 87 2.2E-14 T 23-10-2018 IPR002220 DapA-like GO:0016829 A0127_08725 2ec5da23480e952be75c1a3ff8d808b7 296 PRINTS PR00146 Dihydrodipicolinate synthase signature 101 117 2.2E-14 T 23-10-2018 IPR002220 DapA-like GO:0016829 A0127_08725 2ec5da23480e952be75c1a3ff8d808b7 296 PRINTS PR00146 Dihydrodipicolinate synthase signature 126 143 2.2E-14 T 23-10-2018 IPR002220 DapA-like GO:0016829 A0127_08725 2ec5da23480e952be75c1a3ff8d808b7 296 SUPERFAMILY SSF51569 2 291 1.15E-76 T 23-10-2018 A0127_08920 4897e0ad0692bfdb95e0c9c6acb0e73f 157 Pfam PF09002 Domain of unknown function (DUF1887) 1 125 1.8E-6 T 23-10-2018 IPR015093 Protein of unknown function DUF1887 A0127_08920 4897e0ad0692bfdb95e0c9c6acb0e73f 157 SUPERFAMILY SSF52980 2 117 8.58E-5 T 23-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 A0127_00260 9f2eb7e0295e1ed7be52dbfeec21e155 765 SUPERFAMILY SSF51445 258 691 1.63E-105 T 23-10-2018 IPR017853 Glycoside hydrolase superfamily A0127_00260 9f2eb7e0295e1ed7be52dbfeec21e155 765 Pfam PF16561 Glycogen recognition site of AMP-activated protein kinase 86 147 3.3E-9 T 23-10-2018 IPR032640 AMP-activated protein kinase, glycogen-binding domain Reactome: R-HSA-1445148|Reactome: R-HSA-1632852|Reactome: R-HSA-2151209|Reactome: R-HSA-380972|Reactome: R-HSA-5628897|Reactome: R-HSA-6804756 A0127_00260 9f2eb7e0295e1ed7be52dbfeec21e155 765 SUPERFAMILY SSF81296 90 181 1.54E-14 T 23-10-2018 IPR014756 Immunoglobulin E-set A0127_00260 9f2eb7e0295e1ed7be52dbfeec21e155 765 SMART SM00642 295 684 2.7E-103 T 23-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 A0127_00260 9f2eb7e0295e1ed7be52dbfeec21e155 765 Gene3D G3DSA:3.90.400.10 422 475 2.5E-120 T 23-10-2018 A0127_00260 9f2eb7e0295e1ed7be52dbfeec21e155 765 Gene3D G3DSA:2.60.40.10 79 184 4.9E-18 T 23-10-2018 IPR013783 Immunoglobulin-like fold A0127_00260 9f2eb7e0295e1ed7be52dbfeec21e155 765 Pfam PF11941 Domain of unknown function (DUF3459) 677 748 2.2E-5 T 23-10-2018 IPR022567 Glycosyl hydrolase, C-terminal (DUF3459) A0127_00260 9f2eb7e0295e1ed7be52dbfeec21e155 765 Pfam PF00128 Alpha amylase, catalytic domain 349 654 9.2E-64 T 23-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 A0127_00260 9f2eb7e0295e1ed7be52dbfeec21e155 765 Gene3D G3DSA:3.20.20.80 291 685 2.5E-120 T 23-10-2018 A0127_01195 ffca0c3213285e8b0d69bf1a3ab2bac4 237 Hamap MF_00095 Sugar fermentation stimulation protein A [sfsA]. 5 236 39.492 T 23-10-2018 IPR005224 Sugar fermentation stimulation protein A0127_01195 ffca0c3213285e8b0d69bf1a3ab2bac4 237 Pfam PF03749 Sugar fermentation stimulation protein 17 224 1.3E-50 T 23-10-2018 IPR005224 Sugar fermentation stimulation protein A0127_01195 ffca0c3213285e8b0d69bf1a3ab2bac4 237 Gene3D G3DSA:3.40.1350.60 82 237 1.9E-42 T 23-10-2018 A0127_01195 ffca0c3213285e8b0d69bf1a3ab2bac4 237 Gene3D G3DSA:2.40.50.580 5 81 3.4E-25 T 23-10-2018 A0127_01195 ffca0c3213285e8b0d69bf1a3ab2bac4 237 TIGRFAM TIGR00230 sfsA: sugar fermentation stimulation protein 11 235 6.8E-53 T 23-10-2018 IPR005224 Sugar fermentation stimulation protein A0127_01740 b35caa00ce1122b5d4bbc031c2e7f713 126 SUPERFAMILY SSF54913 8 107 2.41E-34 T 23-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta A0127_01740 b35caa00ce1122b5d4bbc031c2e7f713 126 Pfam PF02641 Uncharacterized ACR, COG1993 11 105 1.4E-39 T 23-10-2018 IPR003793 Domain of unknown function DUF190 A0127_01740 b35caa00ce1122b5d4bbc031c2e7f713 126 Gene3D G3DSA:3.30.70.120 1 126 2.3E-58 T 23-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal A0127_01180 34e8e321b337d4a32ef7fef5b1f7d53c 348 Gene3D G3DSA:2.40.30.40 68 161 1.2E-137 T 23-10-2018 IPR023367 Peptidase M42, domain 2 A0127_01180 34e8e321b337d4a32ef7fef5b1f7d53c 348 Pfam PF05343 M42 glutamyl aminopeptidase 45 335 1.8E-112 T 23-10-2018 IPR008007 Peptidase M42 A0127_01180 34e8e321b337d4a32ef7fef5b1f7d53c 348 PIRSF PIRSF001123 1 348 1.5E-123 T 23-10-2018 IPR008007 Peptidase M42 A0127_01180 34e8e321b337d4a32ef7fef5b1f7d53c 348 SUPERFAMILY SSF53187 5 345 2.6E-70 T 23-10-2018 A0127_01180 34e8e321b337d4a32ef7fef5b1f7d53c 348 SUPERFAMILY SSF101821 68 177 2.9E-31 T 23-10-2018 A0127_01180 34e8e321b337d4a32ef7fef5b1f7d53c 348 Gene3D G3DSA:3.40.630.10 6 336 1.2E-137 T 23-10-2018 A0127_03420 ce2adee1c65463d7c16d918b861a0371 134 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 11 132 7.8E-48 T 23-10-2018 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 A0127_03420 ce2adee1c65463d7c16d918b861a0371 134 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 54 83 - T 23-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 A0127_03420 ce2adee1c65463d7c16d918b861a0371 134 SUPERFAMILY SSF51230 10 133 4.32E-43 T 23-10-2018 IPR011053 Single hybrid motif A0127_03420 ce2adee1c65463d7c16d918b861a0371 134 Pfam PF01597 Glycine cleavage H-protein 13 133 6.2E-51 T 23-10-2018 IPR033753 Glycine cleavage system H-protein/Simiate A0127_03420 ce2adee1c65463d7c16d918b861a0371 134 Gene3D G3DSA:2.40.50.100 2 132 6.5E-53 T 23-10-2018 A0127_03420 ce2adee1c65463d7c16d918b861a0371 134 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 10 132 42.23 T 23-10-2018 IPR002930 Glycine cleavage system H-protein GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 A0127_01555 1fe59ac735c9d9d0043e42a3f1b76699 221 Gene3D G3DSA:1.10.510.10 97 216 5.4E-33 T 23-10-2018 A0127_01555 1fe59ac735c9d9d0043e42a3f1b76699 221 ProSitePatterns PS00109 Tyrosine protein kinases specific active-site signature. 125 137 - T 23-10-2018 IPR008266 Tyrosine-protein kinase, active site GO:0004672|GO:0006468 A0127_01555 1fe59ac735c9d9d0043e42a3f1b76699 221 SMART SM00220 25 220 3.3E-4 T 23-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 A0127_01555 1fe59ac735c9d9d0043e42a3f1b76699 221 TIGRFAM TIGR03724 arch_bud32: Kae1-associated kinase Bud32 4 214 4.3E-74 T 23-10-2018 IPR022495 Serine/threonine-protein kinase Bud32 GO:0004674 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6782315|Reactome: R-HSA-6804756 A0127_01555 1fe59ac735c9d9d0043e42a3f1b76699 221 Gene3D G3DSA:3.30.200.20 9 89 1.1E-25 T 23-10-2018 A0127_01555 1fe59ac735c9d9d0043e42a3f1b76699 221 Pfam PF01163 RIO1 family 47 148 1.0E-15 T 23-10-2018 A0127_01555 1fe59ac735c9d9d0043e42a3f1b76699 221 SUPERFAMILY SSF56112 2 159 1.13E-29 T 23-10-2018 IPR011009 Protein kinase-like domain superfamily A0127_08535 21a6188328c57a53e440e2721c178bf8 249 Gene3D G3DSA:2.20.25.110 149 209 8.6E-37 T 23-10-2018 A0127_08535 21a6188328c57a53e440e2721c178bf8 249 Pfam PF13649 Methyltransferase domain 45 139 4.1E-26 T 23-10-2018 A0127_08535 21a6188328c57a53e440e2721c178bf8 249 Gene3D G3DSA:3.40.50.150 1 148 1.5E-50 T 23-10-2018 A0127_08535 21a6188328c57a53e440e2721c178bf8 249 SUPERFAMILY SSF53335 1 244 2.24E-48 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A0127_04330 9f431f2c465ffd94a8a6c4bf83d2e8cb 380 PIRSF PIRSF038945 28 376 2.3E-83 T 23-10-2018 IPR026260 Threonine synthase, bacterial/archaeal GO:0004795|GO:0009088 KEGG: 00260+4.2.3.1|KEGG: 00750+4.2.3.1 A0127_04330 9f431f2c465ffd94a8a6c4bf83d2e8cb 380 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 57 353 1.1E-72 T 23-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme A0127_04330 9f431f2c465ffd94a8a6c4bf83d2e8cb 380 TIGRFAM TIGR00260 thrC: threonine synthase 49 357 7.1E-62 T 23-10-2018 IPR004450 Threonine synthase-like A0127_04330 9f431f2c465ffd94a8a6c4bf83d2e8cb 380 Gene3D G3DSA:3.40.50.1100 43 358 1.9E-110 T 23-10-2018 A0127_04330 9f431f2c465ffd94a8a6c4bf83d2e8cb 380 Gene3D G3DSA:3.40.50.1100 91 186 1.9E-110 T 23-10-2018 A0127_04330 9f431f2c465ffd94a8a6c4bf83d2e8cb 380 SUPERFAMILY SSF53686 3 362 1.7E-87 T 23-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme A0127_08730 da89e83f7f34638280d297ead14bbf22 642 Pfam PF05746 DALR anticodon binding domain 520 642 4.7E-37 T 23-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 A0127_08730 da89e83f7f34638280d297ead14bbf22 642 Pfam PF00750 tRNA synthetases class I (R) 105 362 1.1E-25 T 23-10-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 A0127_08730 da89e83f7f34638280d297ead14bbf22 642 Pfam PF00750 tRNA synthetases class I (R) 388 494 6.6E-11 T 23-10-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 A0127_08730 da89e83f7f34638280d297ead14bbf22 642 SUPERFAMILY SSF47323 514 642 6.08E-35 T 23-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A0127_08730 da89e83f7f34638280d297ead14bbf22 642 SMART SM00836 520 642 1.6E-51 T 23-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 A0127_08730 da89e83f7f34638280d297ead14bbf22 642 Hamap MF_00123 Arginine--tRNA ligase [argS]. 12 642 27.957 T 23-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 A0127_08730 da89e83f7f34638280d297ead14bbf22 642 PRINTS PR01038 Arginyl-tRNA synthetase signature 330 351 2.2E-23 T 23-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 A0127_08730 da89e83f7f34638280d297ead14bbf22 642 PRINTS PR01038 Arginyl-tRNA synthetase signature 125 140 2.2E-23 T 23-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 A0127_08730 da89e83f7f34638280d297ead14bbf22 642 PRINTS PR01038 Arginyl-tRNA synthetase signature 164 177 2.2E-23 T 23-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 A0127_08730 da89e83f7f34638280d297ead14bbf22 642 PRINTS PR01038 Arginyl-tRNA synthetase signature 140 156 2.2E-23 T 23-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 A0127_08730 da89e83f7f34638280d297ead14bbf22 642 Gene3D G3DSA:1.10.730.10 524 642 1.4E-41 T 23-10-2018 A0127_08730 da89e83f7f34638280d297ead14bbf22 642 Gene3D G3DSA:3.40.50.620 122 523 6.9E-160 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A0127_08730 da89e83f7f34638280d297ead14bbf22 642 SUPERFAMILY SSF55190 7 116 2.62E-19 T 23-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 A0127_08730 da89e83f7f34638280d297ead14bbf22 642 Gene3D G3DSA:3.30.1360.70 6 121 2.3E-31 T 23-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 A0127_08730 da89e83f7f34638280d297ead14bbf22 642 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 14 95 3.8E-14 T 23-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A0127_08730 da89e83f7f34638280d297ead14bbf22 642 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 135 144 - T 23-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A0127_08730 da89e83f7f34638280d297ead14bbf22 642 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 14 365 4.8E-79 T 23-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 A0127_08730 da89e83f7f34638280d297ead14bbf22 642 SMART SM01016 8 95 2.4E-20 T 23-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A0127_08730 da89e83f7f34638280d297ead14bbf22 642 SUPERFAMILY SSF52374 121 513 1.9E-75 T 23-10-2018 A0127_07980 9344f1152a5638dcf9455b19cea08df2 648 Pfam PF16661 Metallo-beta-lactamase superfamily domain 203 351 2.8E-10 T 23-10-2018 IPR001279 Metallo-beta-lactamase A0127_07980 9344f1152a5638dcf9455b19cea08df2 648 Pfam PF10996 Beta-Casp domain 433 556 4.2E-25 T 23-10-2018 IPR022712 Beta-Casp domain A0127_07980 9344f1152a5638dcf9455b19cea08df2 648 SUPERFAMILY SSF56281 183 647 1.77E-133 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A0127_07980 9344f1152a5638dcf9455b19cea08df2 648 Gene3D G3DSA:3.30.300.20 72 142 1.5E-64 T 23-10-2018 IPR015946 K homology domain-like, alpha/beta A0127_07980 9344f1152a5638dcf9455b19cea08df2 648 SUPERFAMILY SSF54814 96 141 2.75E-5 T 23-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 A0127_07980 9344f1152a5638dcf9455b19cea08df2 648 SMART SM00322 102 169 0.0017 T 23-10-2018 IPR004087 K Homology domain GO:0003676 A0127_07980 9344f1152a5638dcf9455b19cea08df2 648 Gene3D G3DSA:3.30.300.230 17 176 1.5E-64 T 23-10-2018 A0127_07980 9344f1152a5638dcf9455b19cea08df2 648 Gene3D G3DSA:3.60.15.10 191 627 6.6E-167 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A0127_07980 9344f1152a5638dcf9455b19cea08df2 648 Pfam PF17214 KH domain 9 76 4.5E-28 T 23-10-2018 IPR033769 KH domain, archaeal A0127_07980 9344f1152a5638dcf9455b19cea08df2 648 TIGRFAM TIGR03675 arCOG00543: arCOG00543 universal archaeal KH-domain/beta-lactamase-domain protein 13 647 5.0E-301 T 23-10-2018 IPR019975 KH-domain/beta-lactamase-domain protein, archaea A0127_07980 9344f1152a5638dcf9455b19cea08df2 648 Gene3D G3DSA:3.40.50.10890 401 588 6.6E-167 T 23-10-2018 A0127_07980 9344f1152a5638dcf9455b19cea08df2 648 SMART SM01027 433 557 7.3E-58 T 23-10-2018 IPR022712 Beta-Casp domain A0127_07980 9344f1152a5638dcf9455b19cea08df2 648 SMART SM00849 198 428 7.0E-25 T 23-10-2018 IPR001279 Metallo-beta-lactamase A0127_07980 9344f1152a5638dcf9455b19cea08df2 648 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 576 639 2.8E-18 T 23-10-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain A0127_07055 67b59a52b085ecb0ff56d27185b5ae6c 234 SMART SM00709 26 186 1.2E-77 T 23-10-2018 IPR004457 Zinc finger, ZPR1-type GO:0008270 A0127_07055 67b59a52b085ecb0ff56d27185b5ae6c 234 TIGRFAM TIGR00310 ZPR1_znf: ZPR1 zinc finger domain 27 205 1.4E-60 T 23-10-2018 IPR004457 Zinc finger, ZPR1-type GO:0008270 A0127_07055 67b59a52b085ecb0ff56d27185b5ae6c 234 TIGRFAM TIGR00340 zpr1_rel: zinc finger protein ZPR1 homolog 28 193 9.8E-68 T 23-10-2018 IPR004470 Zinc finger, ZPR1-type, subgroup GO:0008270 A0127_07055 67b59a52b085ecb0ff56d27185b5ae6c 234 Gene3D G3DSA:2.20.25.420 19 71 3.1E-7 T 23-10-2018 A0127_07055 67b59a52b085ecb0ff56d27185b5ae6c 234 Pfam PF03367 ZPR1 zinc-finger domain 27 183 5.0E-38 T 23-10-2018 IPR004457 Zinc finger, ZPR1-type GO:0008270 A0127_07055 67b59a52b085ecb0ff56d27185b5ae6c 234 Gene3D G3DSA:2.60.120.1040 75 198 1.2E-21 T 23-10-2018 A0127_01580 c8d2ebb1d7524bf34558ae76c2d5d4a6 158 Pfam PF02566 OsmC-like protein 58 148 7.3E-19 T 23-10-2018 IPR003718 OsmC/Ohr family A0127_01580 c8d2ebb1d7524bf34558ae76c2d5d4a6 158 Gene3D G3DSA:3.30.300.20 21 155 1.1E-27 T 23-10-2018 IPR015946 K homology domain-like, alpha/beta A0127_01580 c8d2ebb1d7524bf34558ae76c2d5d4a6 158 SUPERFAMILY SSF82784 18 151 1.96E-28 T 23-10-2018 IPR036102 OsmC/Ohr superfamily A0127_02395 c651967584ce23c9fc1afbb905d04bf1 384 Gene3D G3DSA:3.40.630.10 16 367 1.8E-147 T 23-10-2018 A0127_02395 c651967584ce23c9fc1afbb905d04bf1 384 SUPERFAMILY SSF53187 8 382 1.31E-88 T 23-10-2018 A0127_02395 c651967584ce23c9fc1afbb905d04bf1 384 Gene3D G3DSA:3.30.70.360 178 292 1.8E-147 T 23-10-2018 A0127_02395 c651967584ce23c9fc1afbb905d04bf1 384 Pfam PF07687 Peptidase dimerisation domain 186 275 1.4E-11 T 23-10-2018 IPR011650 Peptidase M20, dimerisation domain A0127_02395 c651967584ce23c9fc1afbb905d04bf1 384 Pfam PF01546 Peptidase family M20/M25/M40 70 372 1.4E-37 T 23-10-2018 IPR002933 Peptidase M20 GO:0016787 A0127_02395 c651967584ce23c9fc1afbb905d04bf1 384 PIRSF PIRSF005962 1 384 2.7E-136 T 23-10-2018 IPR017439 Amidohydrolase GO:0016787 A0127_02395 c651967584ce23c9fc1afbb905d04bf1 384 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 16 370 1.4E-119 T 23-10-2018 IPR017439 Amidohydrolase GO:0016787 A0127_02395 c651967584ce23c9fc1afbb905d04bf1 384 SUPERFAMILY SSF55031 181 287 4.71E-31 T 23-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain A0127_06665 d61f0588548385d0a16cea1f304ed444 80 Pfam PF14076 Domain of unknown function (DUF4258) 7 69 2.4E-17 T 23-10-2018 IPR025354 Protein of unknown function DUF4258 A0127_07465 7328c009e85283db7317789d472919c4 256 Pfam PF02598 Putative RNA methyltransferase 5 249 7.8E-50 T 23-10-2018 IPR003750 Putative RNA methyltransferase A0127_07465 7328c009e85283db7317789d472919c4 256 SUPERFAMILY SSF50249 91 156 1.88E-11 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A0127_07465 7328c009e85283db7317789d472919c4 256 Gene3D G3DSA:3.40.1280.10 5 252 1.5E-76 T 23-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal A0127_07465 7328c009e85283db7317789d472919c4 256 SUPERFAMILY SSF75217 4 254 4.18E-47 T 23-10-2018 IPR029028 Alpha/beta knot methyltransferases A0127_07465 7328c009e85283db7317789d472919c4 256 Gene3D G3DSA:2.40.50.140 91 156 1.5E-76 T 23-10-2018 A0127_05045 b6d74fbae71d2f052134af3cc84859ac 248 Gene3D G3DSA:3.40.50.300 3 241 3.5E-65 T 23-10-2018 A0127_05045 b6d74fbae71d2f052134af3cc84859ac 248 SMART SM00382 28 211 8.4E-16 T 23-10-2018 IPR003593 AAA+ ATPase domain A0127_05045 b6d74fbae71d2f052134af3cc84859ac 248 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A0127_05045 b6d74fbae71d2f052134af3cc84859ac 248 SUPERFAMILY SSF52540 4 219 5.89E-60 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_05045 b6d74fbae71d2f052134af3cc84859ac 248 Pfam PF00005 ABC transporter 19 163 1.0E-28 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A0127_07255 321ace3f511c3ed79ff061a1957dfb12 229 Pfam PF02080 TrkA-C domain 153 221 5.6E-15 T 23-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A0127_07255 321ace3f511c3ed79ff061a1957dfb12 229 SUPERFAMILY SSF116726 135 221 1.57E-13 T 23-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 A0127_07255 321ace3f511c3ed79ff061a1957dfb12 229 Gene3D G3DSA:3.30.70.1450 141 224 1.9E-17 T 23-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 A0127_07255 321ace3f511c3ed79ff061a1957dfb12 229 PRINTS PR00335 TrkA potassium uptake protein signature 19 33 1.8E-12 T 23-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 A0127_07255 321ace3f511c3ed79ff061a1957dfb12 229 PRINTS PR00335 TrkA potassium uptake protein signature 49 59 1.8E-12 T 23-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 A0127_07255 321ace3f511c3ed79ff061a1957dfb12 229 PRINTS PR00335 TrkA potassium uptake protein signature 60 70 1.8E-12 T 23-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 A0127_07255 321ace3f511c3ed79ff061a1957dfb12 229 PRINTS PR00335 TrkA potassium uptake protein signature 2 16 1.8E-12 T 23-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 A0127_07255 321ace3f511c3ed79ff061a1957dfb12 229 PRINTS PR00335 TrkA potassium uptake protein signature 73 87 1.8E-12 T 23-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 A0127_07255 321ace3f511c3ed79ff061a1957dfb12 229 Pfam PF02254 TrkA-N domain 3 124 2.1E-29 T 23-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 A0127_07255 321ace3f511c3ed79ff061a1957dfb12 229 Gene3D G3DSA:3.40.50.720 1 140 3.0E-41 T 23-10-2018 A0127_07255 321ace3f511c3ed79ff061a1957dfb12 229 SUPERFAMILY SSF51735 1 144 4.42E-38 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A0127_02785 bc6f356c5f39dfecd14c2f17b7fa23fd 180 Pfam PF01885 RNA 2'-phosphotransferase, Tpt1 / KptA family 5 168 3.3E-33 T 23-10-2018 IPR002745 Phosphotransferase KptA/Tpt1 GO:0006388|GO:0016772 A0127_02785 bc6f356c5f39dfecd14c2f17b7fa23fd 180 Hamap MF_00299 Probable RNA 2'-phosphotransferase [kptA]. 4 176 34.475 T 23-10-2018 IPR022928 RNA 2'-phosphotransferase KptA, putative GO:0016773 A0127_02785 bc6f356c5f39dfecd14c2f17b7fa23fd 180 Gene3D G3DSA:1.10.10.970 4 75 4.4E-23 T 23-10-2018 A0127_02785 bc6f356c5f39dfecd14c2f17b7fa23fd 180 SUPERFAMILY SSF56399 7 178 1.21E-58 T 23-10-2018 A0127_02785 bc6f356c5f39dfecd14c2f17b7fa23fd 180 Gene3D G3DSA:3.20.170.30 95 180 4.4E-31 T 23-10-2018 A0127_04615 988c1e394ff948b59ac34efb0472aa50 368 SUPERFAMILY SSF82861 99 182 8.37E-8 T 23-10-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 A0127_04615 988c1e394ff948b59ac34efb0472aa50 368 ProSitePatterns PS01246 Uncharacterized protein family UPF0003 signature. 213 247 - T 23-10-2018 IPR006686 Mechanosensitive ion channel MscS, conserved site GO:0016020 A0127_04615 988c1e394ff948b59ac34efb0472aa50 368 Pfam PF00924 Mechanosensitive ion channel 139 343 2.8E-57 T 23-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 A0127_04615 988c1e394ff948b59ac34efb0472aa50 368 Gene3D G3DSA:2.30.30.60 199 248 1.8E-13 T 23-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily A0127_04615 988c1e394ff948b59ac34efb0472aa50 368 Gene3D G3DSA:3.30.70.100 250 347 6.9E-27 T 23-10-2018 A0127_04615 988c1e394ff948b59ac34efb0472aa50 368 SUPERFAMILY SSF82689 252 352 5.75E-29 T 23-10-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 A0127_04615 988c1e394ff948b59ac34efb0472aa50 368 SUPERFAMILY SSF50182 184 248 3.14E-18 T 23-10-2018 IPR010920 LSM domain superfamily A0127_08105 ec4d4811104a69ea8f36047243cf0fae 573 Gene3D G3DSA:2.40.240.100 410 572 2.8E-42 T 23-10-2018 A0127_08105 ec4d4811104a69ea8f36047243cf0fae 573 TIGRFAM TIGR00463 gltX_arch: glutamate--tRNA ligase 6 573 8.6E-215 T 23-10-2018 IPR004526 Glutamyl-tRNA synthetase, archaeal/eukaryotic cytosolic GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 A0127_08105 ec4d4811104a69ea8f36047243cf0fae 573 Gene3D G3DSA:3.40.50.620 94 409 2.7E-120 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A0127_08105 ec4d4811104a69ea8f36047243cf0fae 573 SUPERFAMILY SSF52374 100 416 4.56E-91 T 23-10-2018 A0127_08105 ec4d4811104a69ea8f36047243cf0fae 573 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 100 404 4.3E-85 T 23-10-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0004812|GO:0005524|GO:0043039 A0127_08105 ec4d4811104a69ea8f36047243cf0fae 573 PRINTS PR00987 Glutamyl-tRNA synthetase signature 118 129 3.7E-21 T 23-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 A0127_08105 ec4d4811104a69ea8f36047243cf0fae 573 PRINTS PR00987 Glutamyl-tRNA synthetase signature 104 116 3.7E-21 T 23-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 A0127_08105 ec4d4811104a69ea8f36047243cf0fae 573 PRINTS PR00987 Glutamyl-tRNA synthetase signature 133 146 3.7E-21 T 23-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 A0127_08105 ec4d4811104a69ea8f36047243cf0fae 573 PRINTS PR00987 Glutamyl-tRNA synthetase signature 281 291 3.7E-21 T 23-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 A0127_08105 ec4d4811104a69ea8f36047243cf0fae 573 PRINTS PR00987 Glutamyl-tRNA synthetase signature 297 305 3.7E-21 T 23-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 A0127_08105 ec4d4811104a69ea8f36047243cf0fae 573 Pfam PF03950 tRNA synthetases class I (E and Q), anti-codon binding domain 410 559 7.4E-29 T 23-10-2018 IPR020059 Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A0127_08105 ec4d4811104a69ea8f36047243cf0fae 573 Hamap MF_02076 Glutamate--tRNA ligase [gltX]. 8 571 40.243 T 23-10-2018 IPR004526 Glutamyl-tRNA synthetase, archaeal/eukaryotic cytosolic GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 A0127_08105 ec4d4811104a69ea8f36047243cf0fae 573 Gene3D G3DSA:2.40.240.10 419 517 2.8E-42 T 23-10-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, N-terminal Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A0127_08105 ec4d4811104a69ea8f36047243cf0fae 573 SUPERFAMILY SSF50715 410 570 5.75E-30 T 23-10-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A0127_05575 0446d484f229f2eae9645caffddf5adf 165 SUPERFAMILY SSF52374 3 147 7.6E-21 T 23-10-2018 A0127_05575 0446d484f229f2eae9645caffddf5adf 165 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 8 67 5.4E-13 T 23-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 A0127_05575 0446d484f229f2eae9645caffddf5adf 165 Pfam PF01467 Cytidylyltransferase-like 9 145 2.8E-17 T 23-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 A0127_05575 0446d484f229f2eae9645caffddf5adf 165 Hamap MF_00647 Phosphopantetheine adenylyltransferase [coaD]. 6 156 33.27 T 23-10-2018 IPR023540 Phosphopantetheine adenylyltransferase, archaea GO:0004595 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 A0127_05575 0446d484f229f2eae9645caffddf5adf 165 Gene3D G3DSA:3.40.50.620 6 154 9.2E-41 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A0127_08200 7dcf167f79a3ff45c53d0e521b429e60 225 Gene3D G3DSA:3.60.21.10 15 159 7.2E-11 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like A0127_08200 7dcf167f79a3ff45c53d0e521b429e60 225 SUPERFAMILY SSF56300 17 148 3.19E-16 T 23-10-2018 A0127_08200 7dcf167f79a3ff45c53d0e521b429e60 225 PIRSF PIRSF000887 4 223 2.9E-59 T 23-10-2018 IPR024173 Phosphoesterase, MJ0037 A0127_08200 7dcf167f79a3ff45c53d0e521b429e60 225 TIGRFAM TIGR00024 SbcD_rel_arch: putative phosphoesterase 7 219 1.3E-49 T 23-10-2018 IPR004376 Conserved hypothetical protein CHP00024, phosphoesterase-like A0127_08200 7dcf167f79a3ff45c53d0e521b429e60 225 Pfam PF00149 Calcineurin-like phosphoesterase 17 112 4.5E-7 T 23-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 A0127_04465 108eec4184da4214465bb62060269345 644 TIGRFAM TIGR04288 CGP_CTERM: CGP-CTERM domain 625 644 4.7E-7 T 23-10-2018 IPR027552 CGP-CTERM domain A0127_04465 108eec4184da4214465bb62060269345 644 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 78 182 1.8E-12 T 23-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 A0127_04465 108eec4184da4214465bb62060269345 644 Gene3D G3DSA:3.30.230.10 33 235 8.1E-28 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A0127_04465 108eec4184da4214465bb62060269345 644 SUPERFAMILY SSF54211 49 234 3.72E-25 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A0127_08470 022b09f1ee18b2e723dd859b545eda5a 90 Hamap MF_00410 50S ribosomal protein L31e [rpl31e]. 4 90 21.369 T 23-10-2018 IPR000054 Ribosomal protein L31e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_08470 022b09f1ee18b2e723dd859b545eda5a 90 Pfam PF01198 Ribosomal protein L31e 13 79 2.0E-9 T 23-10-2018 IPR000054 Ribosomal protein L31e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_08470 022b09f1ee18b2e723dd859b545eda5a 90 ProDom PD006030 RIBOSOMAL 60S L31 RIBONUCLEOPROTEIN L31E 50S L31 SUBUNIT STRAIN PHOSPHORYLATION 13 58 9.0E-19 T 23-10-2018 IPR000054 Ribosomal protein L31e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_08470 022b09f1ee18b2e723dd859b545eda5a 90 ProSitePatterns PS01144 Ribosomal protein L31e signature. 48 62 - T 23-10-2018 IPR020052 Ribosomal protein L31e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_08470 022b09f1ee18b2e723dd859b545eda5a 90 SUPERFAMILY SSF54575 7 84 2.75E-22 T 23-10-2018 IPR023621 Ribosomal protein L31e domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_08470 022b09f1ee18b2e723dd859b545eda5a 90 SMART SM01380 8 82 3.2E-19 T 23-10-2018 IPR000054 Ribosomal protein L31e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_08470 022b09f1ee18b2e723dd859b545eda5a 90 Gene3D G3DSA:3.10.440.10 2 90 2.5E-25 T 23-10-2018 IPR023621 Ribosomal protein L31e domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_06995 046b133f101dd6f8c8ac7cafcea36c77 637 TIGRFAM TIGR03336 IOR_alpha: indolepyruvate ferredoxin oxidoreductase, alpha subunit 21 627 1.1E-219 T 23-10-2018 IPR017721 Indolepyruvate ferredoxin oxidoreductase, alpha subunit GO:0043805|GO:0055114 A0127_06995 046b133f101dd6f8c8ac7cafcea36c77 637 SUPERFAMILY SSF52922 246 332 2.22E-7 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A0127_06995 046b133f101dd6f8c8ac7cafcea36c77 637 Gene3D G3DSA:3.30.70.20 570 637 1.0E-10 T 23-10-2018 A0127_06995 046b133f101dd6f8c8ac7cafcea36c77 637 Gene3D G3DSA:3.40.50.970 7 198 2.1E-54 T 23-10-2018 A0127_06995 046b133f101dd6f8c8ac7cafcea36c77 637 PIRSF PIRSF006439 10 634 4.7E-223 T 23-10-2018 IPR017721 Indolepyruvate ferredoxin oxidoreductase, alpha subunit GO:0043805|GO:0055114 A0127_06995 046b133f101dd6f8c8ac7cafcea36c77 637 SUPERFAMILY SSF52518 377 562 2.45E-38 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold A0127_06995 046b133f101dd6f8c8ac7cafcea36c77 637 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 612 623 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A0127_06995 046b133f101dd6f8c8ac7cafcea36c77 637 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 414 555 1.5E-32 T 23-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 A0127_06995 046b133f101dd6f8c8ac7cafcea36c77 637 SUPERFAMILY SSF52518 19 248 1.13E-56 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold A0127_06995 046b133f101dd6f8c8ac7cafcea36c77 637 SUPERFAMILY SSF54862 568 630 3.32E-13 T 23-10-2018 A0127_06995 046b133f101dd6f8c8ac7cafcea36c77 637 Pfam PF00037 4Fe-4S binding domain 605 628 6.3E-7 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A0127_06995 046b133f101dd6f8c8ac7cafcea36c77 637 Gene3D G3DSA:3.40.50.970 412 569 1.7E-24 T 23-10-2018 A0127_06995 046b133f101dd6f8c8ac7cafcea36c77 637 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 33 215 2.0E-14 T 23-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 A0127_06970 587e93bebce409c4cac5c5e80b76f7ff 178 Gene3D G3DSA:3.40.50.850 1 178 1.6E-73 T 23-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 A0127_06970 587e93bebce409c4cac5c5e80b76f7ff 178 Pfam PF00857 Isochorismatase family 5 177 4.9E-46 T 23-10-2018 IPR000868 Isochorismatase-like GO:0003824 A0127_06970 587e93bebce409c4cac5c5e80b76f7ff 178 SUPERFAMILY SSF52499 3 177 3.14E-55 T 23-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 A0127_02385 9004acb4893c6b0327c0dc16565e7664 438 SUPERFAMILY SSF50249 1 102 2.57E-27 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A0127_02385 9004acb4893c6b0327c0dc16565e7664 438 PRINTS PR01042 Aspartyl-tRNA synthetase signature 393 407 1.7E-23 T 23-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A0127_02385 9004acb4893c6b0327c0dc16565e7664 438 PRINTS PR01042 Aspartyl-tRNA synthetase signature 204 217 1.7E-23 T 23-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A0127_02385 9004acb4893c6b0327c0dc16565e7664 438 PRINTS PR01042 Aspartyl-tRNA synthetase signature 187 199 1.7E-23 T 23-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A0127_02385 9004acb4893c6b0327c0dc16565e7664 438 PRINTS PR01042 Aspartyl-tRNA synthetase signature 353 369 1.7E-23 T 23-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 A0127_02385 9004acb4893c6b0327c0dc16565e7664 438 Pfam PF00152 tRNA synthetases class II (D, K and N) 118 432 1.1E-96 T 23-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 A0127_02385 9004acb4893c6b0327c0dc16565e7664 438 Pfam PF01336 OB-fold nucleic acid binding domain 19 97 1.0E-11 T 23-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 A0127_02385 9004acb4893c6b0327c0dc16565e7664 438 TIGRFAM TIGR00458 aspS_nondisc: aspartate--tRNA(Asn) ligase 5 438 3.0E-185 T 23-10-2018 IPR004523 Aspartate-tRNA synthetase, type 2 GO:0000166|GO:0004815|GO:0005524|GO:0005737|GO:0006422 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A0127_02385 9004acb4893c6b0327c0dc16565e7664 438 Hamap MF_02075 Aspartate--tRNA(Asp) ligase [aspS]. 2 438 43.57 T 23-10-2018 IPR004523 Aspartate-tRNA synthetase, type 2 GO:0000166|GO:0004815|GO:0005524|GO:0005737|GO:0006422 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A0127_02385 9004acb4893c6b0327c0dc16565e7664 438 Gene3D G3DSA:2.40.50.140 1 105 1.3E-27 T 23-10-2018 A0127_02385 9004acb4893c6b0327c0dc16565e7664 438 SUPERFAMILY SSF55681 95 437 1.91E-100 T 23-10-2018 A0127_02385 9004acb4893c6b0327c0dc16565e7664 438 Gene3D G3DSA:3.30.930.10 107 438 1.4E-122 T 23-10-2018 A0127_00590 4453130b5161e9bca45a6e0dc5c877a3 206 Gene3D G3DSA:1.10.150.280 93 190 4.6E-43 T 23-10-2018 A0127_00590 4453130b5161e9bca45a6e0dc5c877a3 206 Gene3D G3DSA:2.40.50.140 23 92 3.7E-22 T 23-10-2018 A0127_00590 4453130b5161e9bca45a6e0dc5c877a3 206 Pfam PF04919 Protein of unknown function (DUF655) 23 198 2.0E-69 T 23-10-2018 IPR007003 Protein of unknown function DUF655 A0127_00590 4453130b5161e9bca45a6e0dc5c877a3 206 SUPERFAMILY SSF160975 23 199 2.35E-92 T 23-10-2018 A0127_05075 2ce23a17759b1ffc8918b5a85280b2ff 322 SUPERFAMILY SSF52540 4 235 2.4E-60 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_05075 2ce23a17759b1ffc8918b5a85280b2ff 322 SMART SM00382 39 232 9.6E-16 T 23-10-2018 IPR003593 AAA+ ATPase domain A0127_05075 2ce23a17759b1ffc8918b5a85280b2ff 322 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 27 317 7.1E-100 T 23-10-2018 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 A0127_05075 2ce23a17759b1ffc8918b5a85280b2ff 322 Gene3D G3DSA:3.40.50.300 1 262 1.1E-65 T 23-10-2018 A0127_05075 2ce23a17759b1ffc8918b5a85280b2ff 322 Pfam PF00005 ABC transporter 31 174 3.0E-29 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A0127_05075 2ce23a17759b1ffc8918b5a85280b2ff 322 Pfam PF13732 Domain of unknown function (DUF4162) 242 316 7.7E-7 T 23-10-2018 IPR025302 Domain of unknown function DUF4162 A0127_07360 41cd22692c0b1e9a832d77225490c8eb 211 Gene3D G3DSA:3.40.50.11570 7 209 6.7E-40 T 23-10-2018 A0127_07360 41cd22692c0b1e9a832d77225490c8eb 211 Pfam PF03192 Pyrococcus protein of unknown function, DUF257 13 206 1.1E-27 T 23-10-2018 IPR005489 Protein of unknown function DUF257 A0127_05830 4633367a0e2c9136e253c53ac71d297a 258 Gene3D G3DSA:3.60.15.10 1 258 1.3E-49 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A0127_05830 4633367a0e2c9136e253c53ac71d297a 258 Pfam PF12706 Beta-lactamase superfamily domain 46 226 1.5E-23 T 23-10-2018 IPR001279 Metallo-beta-lactamase A0127_05830 4633367a0e2c9136e253c53ac71d297a 258 SMART SM00849 36 225 1.0E-12 T 23-10-2018 IPR001279 Metallo-beta-lactamase A0127_05830 4633367a0e2c9136e253c53ac71d297a 258 SUPERFAMILY SSF56281 1 257 3.01E-45 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A0127_04350 0fdfd6bd9d7ea6d6b622effe432ee362 137 PIRSF PIRSF004681 1 137 2.5E-38 T 23-10-2018 IPR001602 Uncharacterised protein family UPF0047 A0127_04350 0fdfd6bd9d7ea6d6b622effe432ee362 137 SUPERFAMILY SSF111038 1 137 1.44E-44 T 23-10-2018 IPR035917 YjbQ-like superfamily A0127_04350 0fdfd6bd9d7ea6d6b622effe432ee362 137 Pfam PF01894 Uncharacterised protein family UPF0047 20 134 1.5E-36 T 23-10-2018 IPR001602 Uncharacterised protein family UPF0047 A0127_04350 0fdfd6bd9d7ea6d6b622effe432ee362 137 Gene3D G3DSA:2.60.120.460 1 137 2.1E-50 T 23-10-2018 IPR035917 YjbQ-like superfamily A0127_04350 0fdfd6bd9d7ea6d6b622effe432ee362 137 TIGRFAM TIGR00149 TIGR00149_YjbQ: secondary thiamine-phosphate synthase enzyme 10 137 1.7E-38 T 23-10-2018 IPR001602 Uncharacterised protein family UPF0047 A0127_08900 cb08db7fbd92576ec4361dac268d8b98 182 Pfam PF01161 Phosphatidylethanolamine-binding protein 42 179 8.3E-36 T 23-10-2018 IPR008914 Phosphatidylethanolamine-binding protein A0127_08900 cb08db7fbd92576ec4361dac268d8b98 182 Gene3D G3DSA:3.90.280.10 32 182 1.0E-53 T 23-10-2018 IPR036610 PEBP-like superfamily A0127_08900 cb08db7fbd92576ec4361dac268d8b98 182 TIGRFAM TIGR00481 TIGR00481: Raf kinase inhibitor-like protein, YbhB/YbcL family 47 179 1.6E-43 T 23-10-2018 IPR005247 YbhB/YbcL A0127_08900 cb08db7fbd92576ec4361dac268d8b98 182 SUPERFAMILY SSF49777 34 181 4.84E-47 T 23-10-2018 IPR036610 PEBP-like superfamily A0127_07535 f6a31fff768adba7ed216a33b02e6284 243 Gene3D G3DSA:2.30.30.30 179 243 4.0E-19 T 23-10-2018 IPR014722 Ribosomal protein L2, domain 2 A0127_07535 f6a31fff768adba7ed216a33b02e6284 243 ProSitePatterns PS00528 Ribosomal protein S4e signature. 9 23 - T 23-10-2018 IPR018199 Ribosomal protein S4e, N-terminal, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_07535 f6a31fff768adba7ed216a33b02e6284 243 Pfam PF08071 RS4NT (NUC023) domain 4 39 2.2E-17 T 23-10-2018 IPR013843 Ribosomal protein S4e, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_07535 f6a31fff768adba7ed216a33b02e6284 243 Gene3D G3DSA:2.40.50.740 123 177 2.2E-17 T 23-10-2018 IPR038237 Ribosomal protein S4e, central domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_07535 f6a31fff768adba7ed216a33b02e6284 243 SMART SM00363 43 107 1.4E-9 T 23-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_07535 f6a31fff768adba7ed216a33b02e6284 243 PIRSF PIRSF002116 2 243 1.1E-101 T 23-10-2018 IPR000876 Ribosomal protein S4e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_07535 f6a31fff768adba7ed216a33b02e6284 243 ProDom PD002667 RIBOSOMAL RIBONUCLEOPROTEIN RNA-BINDING 40S S4 S4 S4E 30S ISOFORM X 88 182 3.0E-40 T 23-10-2018 IPR013845 Ribosomal protein S4e, central region Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_07535 f6a31fff768adba7ed216a33b02e6284 243 SUPERFAMILY SSF55174 52 96 1.83E-7 T 23-10-2018 A0127_07535 f6a31fff768adba7ed216a33b02e6284 243 Gene3D G3DSA:3.10.290.40 1 118 5.7E-51 T 23-10-2018 A0127_07535 f6a31fff768adba7ed216a33b02e6284 243 Pfam PF01479 S4 domain 52 91 5.3E-13 T 23-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_07535 f6a31fff768adba7ed216a33b02e6284 243 Hamap MF_00485 30S ribosomal protein S4e [rps4e]. 8 242 43.267 T 23-10-2018 IPR000876 Ribosomal protein S4e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_07535 f6a31fff768adba7ed216a33b02e6284 243 Pfam PF00900 Ribosomal family S4e 96 173 3.1E-24 T 23-10-2018 IPR013845 Ribosomal protein S4e, central region Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_00200 b9696bc89db625510d1a8321eb599a7f 245 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 8 234 4.6E-22 T 23-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase A0127_00200 b9696bc89db625510d1a8321eb599a7f 245 SUPERFAMILY SSF56219 4 244 1.83E-42 T 23-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily A0127_00200 b9696bc89db625510d1a8321eb599a7f 245 Gene3D G3DSA:3.60.10.10 2 243 2.1E-50 T 23-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily A0127_06535 a5c6e5875ed47906daabfe9fcc7c7010 352 Pfam PF00535 Glycosyl transferase family 2 80 141 2.1E-12 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A0127_06535 a5c6e5875ed47906daabfe9fcc7c7010 352 Pfam PF00535 Glycosyl transferase family 2 7 53 6.5E-11 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A0127_06535 a5c6e5875ed47906daabfe9fcc7c7010 352 Gene3D G3DSA:3.90.550.10 1 254 4.6E-33 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A0127_06535 a5c6e5875ed47906daabfe9fcc7c7010 352 SUPERFAMILY SSF53448 3 305 2.91E-40 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A0127_09040 a6a1056180bd2bdba25cfca80af44d57 183 ProDom PD009560 CYCLASE ADENYLATE CYCLASE ADENYLYL CYAB LYASE CLASS CYAB-TYPE THERMOPHILIC MJ0240 1 152 3.0E-71 T 23-10-2018 A0127_09040 a6a1056180bd2bdba25cfca80af44d57 183 Pfam PF01928 CYTH domain 2 169 1.6E-36 T 23-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 A0127_09040 a6a1056180bd2bdba25cfca80af44d57 183 SUPERFAMILY SSF55154 2 177 1.16E-37 T 23-10-2018 IPR033469 CYTH-like domain superfamily Reactome: R-HSA-196819 A0127_09040 a6a1056180bd2bdba25cfca80af44d57 183 TIGRFAM TIGR00318 cyaB: putative adenylyl cyclase CyaB 2 173 2.8E-44 T 23-10-2018 IPR008173 Adenylyl cyclase CyaB KEGG: 00230+4.6.1.1 A0127_09040 a6a1056180bd2bdba25cfca80af44d57 183 SMART SM01118 1 175 9.1E-24 T 23-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 A0127_09040 a6a1056180bd2bdba25cfca80af44d57 183 Gene3D G3DSA:2.40.320.10 1 180 1.5E-56 T 23-10-2018 A0127_04975 f2c6ad5a17a1d57ebc397a3ab5d6d8e4 118 Pfam PF02627 Carboxymuconolactone decarboxylase family 29 107 4.1E-19 T 23-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 A0127_04975 f2c6ad5a17a1d57ebc397a3ab5d6d8e4 118 SUPERFAMILY SSF69118 11 109 2.22E-27 T 23-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 A0127_04975 f2c6ad5a17a1d57ebc397a3ab5d6d8e4 118 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 43 86 8.4E-12 T 23-10-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 A0127_04975 f2c6ad5a17a1d57ebc397a3ab5d6d8e4 118 Gene3D G3DSA:1.20.1290.10 2 114 2.0E-29 T 23-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 A0127_06075 e053a2210e961d282b9ad1b7b0582cb1 386 Gene3D G3DSA:3.90.1150.10 6 374 1.0E-127 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A0127_06075 e053a2210e961d282b9ad1b7b0582cb1 386 Hamap MF_01610 Probable L-tyrosine/L-aspartate decarboxylase [mfnA]. 14 381 51.173 T 23-10-2018 IPR020931 Decarboxylase MfnA, archaea GO:0016831 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 A0127_06075 e053a2210e961d282b9ad1b7b0582cb1 386 TIGRFAM TIGR03812 tyr_de_CO2_Arch: tyrosine decarboxylase MnfA 8 380 3.5E-170 T 23-10-2018 IPR020931 Decarboxylase MfnA, archaea GO:0016831 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 A0127_06075 e053a2210e961d282b9ad1b7b0582cb1 386 Gene3D G3DSA:3.40.640.10 40 290 1.0E-127 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A0127_06075 e053a2210e961d282b9ad1b7b0582cb1 386 ProSitePatterns PS00392 DDC / GAD / HDC / TyrDC pyridoxal-phosphate attachment site. 224 245 - T 23-10-2018 IPR021115 Pyridoxal-phosphate binding site GO:0016831 A0127_06075 e053a2210e961d282b9ad1b7b0582cb1 386 SUPERFAMILY SSF53383 2 382 2.26E-105 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A0127_06075 e053a2210e961d282b9ad1b7b0582cb1 386 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 66 331 1.1E-36 T 23-10-2018 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 A0127_07075 226267ab0c6ddd6119c34b4d70f2bfdd 280 SMART SM00116 10 58 3.3E-8 T 23-10-2018 IPR000644 CBS domain A0127_07075 226267ab0c6ddd6119c34b4d70f2bfdd 280 SMART SM00116 135 183 7.2 T 23-10-2018 IPR000644 CBS domain A0127_07075 226267ab0c6ddd6119c34b4d70f2bfdd 280 SMART SM00116 230 278 1.3E-9 T 23-10-2018 IPR000644 CBS domain A0127_07075 226267ab0c6ddd6119c34b4d70f2bfdd 280 SMART SM00116 69 117 2.7E-9 T 23-10-2018 IPR000644 CBS domain A0127_07075 226267ab0c6ddd6119c34b4d70f2bfdd 280 Pfam PF00571 CBS domain 3 54 2.6E-11 T 23-10-2018 IPR000644 CBS domain A0127_07075 226267ab0c6ddd6119c34b4d70f2bfdd 280 Pfam PF00571 CBS domain 67 115 1.7E-11 T 23-10-2018 IPR000644 CBS domain A0127_07075 226267ab0c6ddd6119c34b4d70f2bfdd 280 Pfam PF00571 CBS domain 223 278 6.5E-11 T 23-10-2018 IPR000644 CBS domain A0127_07075 226267ab0c6ddd6119c34b4d70f2bfdd 280 Pfam PF00571 CBS domain 138 180 2.9E-5 T 23-10-2018 IPR000644 CBS domain A0127_07075 226267ab0c6ddd6119c34b4d70f2bfdd 280 SUPERFAMILY SSF54631 1 117 2.53E-29 T 23-10-2018 A0127_07075 226267ab0c6ddd6119c34b4d70f2bfdd 280 SUPERFAMILY SSF54631 124 277 5.84E-30 T 23-10-2018 A0127_07075 226267ab0c6ddd6119c34b4d70f2bfdd 280 Gene3D G3DSA:3.10.580.10 122 280 5.2E-35 T 23-10-2018 A0127_07075 226267ab0c6ddd6119c34b4d70f2bfdd 280 Gene3D G3DSA:3.10.580.10 1 121 1.3E-41 T 23-10-2018 A0127_07540 4fc7269cb5de65b2b4f429322558d840 183 Gene3D G3DSA:3.30.1440.10 10 181 1.2E-71 T 23-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_07540 4fc7269cb5de65b2b4f429322558d840 183 Pfam PF00281 Ribosomal protein L5 16 68 4.2E-20 T 23-10-2018 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_07540 4fc7269cb5de65b2b4f429322558d840 183 Hamap MF_01333_A 50S ribosomal protein L5 [rplE]. 14 181 41.638 T 23-10-2018 IPR022804 Ribosomal protein L5, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 A0127_07540 4fc7269cb5de65b2b4f429322558d840 183 SUPERFAMILY SSF55282 15 178 4.71E-57 T 23-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_07540 4fc7269cb5de65b2b4f429322558d840 183 Pfam PF00673 ribosomal L5P family C-terminus 72 171 1.2E-25 T 23-10-2018 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_07540 4fc7269cb5de65b2b4f429322558d840 183 PIRSF PIRSF002161 2 180 1.2E-55 T 23-10-2018 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_09360 923f87ba1d99fceadf57ea81d5539c10 112 Gene3D G3DSA:3.40.50.300 8 108 4.4E-25 T 23-10-2018 A0127_09360 923f87ba1d99fceadf57ea81d5539c10 112 SUPERFAMILY SSF52540 9 93 9.37E-24 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_08160 bdd6542826bee836ac2a594f1985cd9d 495 SUPERFAMILY SSF53067 4 248 2.68E-95 T 23-10-2018 A0127_08160 bdd6542826bee836ac2a594f1985cd9d 495 PIRSF PIRSF000538 2 492 4.5E-180 T 23-10-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 A0127_08160 bdd6542826bee836ac2a594f1985cd9d 495 Gene3D G3DSA:3.30.420.40 248 494 1.4E-95 T 23-10-2018 A0127_08160 bdd6542826bee836ac2a594f1985cd9d 495 SUPERFAMILY SSF53067 249 487 6.66E-85 T 23-10-2018 A0127_08160 bdd6542826bee836ac2a594f1985cd9d 495 TIGRFAM TIGR01311 glycerol_kin: glycerol kinase 3 487 2.0E-216 T 23-10-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 A0127_08160 bdd6542826bee836ac2a594f1985cd9d 495 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 355 375 - T 23-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 A0127_08160 bdd6542826bee836ac2a594f1985cd9d 495 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 5 246 1.9E-87 T 23-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 A0127_08160 bdd6542826bee836ac2a594f1985cd9d 495 Gene3D G3DSA:3.30.420.40 1 247 4.9E-116 T 23-10-2018 A0127_08160 bdd6542826bee836ac2a594f1985cd9d 495 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 256 441 7.0E-55 T 23-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 A0127_08160 bdd6542826bee836ac2a594f1985cd9d 495 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 132 144 - T 23-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 A0127_08160 bdd6542826bee836ac2a594f1985cd9d 495 Hamap MF_00186 Glycerol kinase [glpK]. 2 488 57.484 T 23-10-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 A0127_04445 411cc0197deff5cd2fe99f5768ba5861 713 Gene3D G3DSA:3.20.20.80 22 416 1.1E-105 T 23-10-2018 A0127_04445 411cc0197deff5cd2fe99f5768ba5861 713 SMART SM00642 31 414 1.4E-77 T 23-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 A0127_04445 411cc0197deff5cd2fe99f5768ba5861 713 Pfam PF02806 Alpha amylase, C-terminal all-beta domain 435 499 8.1E-7 T 23-10-2018 IPR006048 Alpha-amylase/branching enzyme, C-terminal all beta GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900 A0127_04445 411cc0197deff5cd2fe99f5768ba5861 713 Pfam PF01833 IPT/TIG domain 506 584 1.3E-7 T 23-10-2018 IPR002909 IPT domain A0127_04445 411cc0197deff5cd2fe99f5768ba5861 713 Gene3D G3DSA:2.60.40.10 505 580 3.0E-12 T 23-10-2018 IPR013783 Immunoglobulin-like fold A0127_04445 411cc0197deff5cd2fe99f5768ba5861 713 Pfam PF00128 Alpha amylase, catalytic domain 62 381 5.3E-53 T 23-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 A0127_04445 411cc0197deff5cd2fe99f5768ba5861 713 SUPERFAMILY SSF51011 423 502 2.09E-15 T 23-10-2018 A0127_04445 411cc0197deff5cd2fe99f5768ba5861 713 SMART SM00632 433 502 0.0027 T 23-10-2018 IPR031319 Alpha-amylase, C-terminal domain Reactome: R-HSA-189085 A0127_04445 411cc0197deff5cd2fe99f5768ba5861 713 PRINTS PR00110 Alpha-amylase signature 133 144 2.3E-5 T 23-10-2018 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 A0127_04445 411cc0197deff5cd2fe99f5768ba5861 713 PRINTS PR00110 Alpha-amylase signature 234 245 2.3E-5 T 23-10-2018 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 A0127_04445 411cc0197deff5cd2fe99f5768ba5861 713 PRINTS PR00110 Alpha-amylase signature 329 341 2.3E-5 T 23-10-2018 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 A0127_04445 411cc0197deff5cd2fe99f5768ba5861 713 SUPERFAMILY SSF51445 24 420 8.26E-81 T 23-10-2018 IPR017853 Glycoside hydrolase superfamily A0127_04445 411cc0197deff5cd2fe99f5768ba5861 713 Gene3D G3DSA:2.60.40.1180 417 500 2.9E-12 T 23-10-2018 IPR013780 Glycosyl hydrolase, all-beta A0127_04445 411cc0197deff5cd2fe99f5768ba5861 713 SUPERFAMILY SSF81296 505 577 8.82E-12 T 23-10-2018 IPR014756 Immunoglobulin E-set A0127_03550 f65e43963b96c7ba50b089105e71d4be 633 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 9 205 5.2E-66 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 A0127_03550 f65e43963b96c7ba50b089105e71d4be 633 SUPERFAMILY SSF48310 213 629 5.75E-120 T 23-10-2018 IPR036021 Aldehyde ferredoxin oxidoreductase-like, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 A0127_03550 f65e43963b96c7ba50b089105e71d4be 633 Gene3D G3DSA:1.10.599.10 239 622 3.3E-133 T 23-10-2018 IPR013985 Aldehyde ferredoxin oxidoreductase, domain 3 GO:0016625|GO:0051536|GO:0055114 KEGG: 00030+1.2.7.5 A0127_03550 f65e43963b96c7ba50b089105e71d4be 633 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 220 622 1.5E-127 T 23-10-2018 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 A0127_03550 f65e43963b96c7ba50b089105e71d4be 633 Gene3D G3DSA:3.60.9.10 5 211 1.9E-70 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily A0127_03550 f65e43963b96c7ba50b089105e71d4be 633 SUPERFAMILY SSF56228 6 209 2.09E-62 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily A0127_03550 f65e43963b96c7ba50b089105e71d4be 633 SMART SM00790 7 207 2.3E-105 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 A0127_03550 f65e43963b96c7ba50b089105e71d4be 633 Gene3D G3DSA:1.10.569.10 241 444 3.3E-133 T 23-10-2018 IPR013984 Aldehyde ferredoxin oxidoreductase, domain 2 A0127_09755 ca45b4d7cce18a98279e6765522868a1 399 Pfam PF00155 Aminotransferase class I and II 31 387 1.0E-59 T 23-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A0127_09755 ca45b4d7cce18a98279e6765522868a1 399 Gene3D G3DSA:3.40.640.10 53 294 1.7E-144 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A0127_09755 ca45b4d7cce18a98279e6765522868a1 399 SUPERFAMILY SSF53383 12 395 1.73E-106 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A0127_09755 ca45b4d7cce18a98279e6765522868a1 399 Gene3D G3DSA:3.90.1150.10 24 390 1.7E-144 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A0127_09755 ca45b4d7cce18a98279e6765522868a1 399 PIRSF PIRSF000517 3 399 3.1E-78 T 23-10-2018 IPR005958 Tyrosine/nicotianamine aminotransferase GO:0006520|GO:0008483|GO:0030170 Reactome: R-HSA-71182 A0127_09800 e93b6b1332c843d473bc6a1395026868 226 Pfam PF05768 Glutaredoxin-like domain (DUF836) 27 75 1.3E-4 T 23-10-2018 IPR008554 Glutaredoxin-like A0127_09800 e93b6b1332c843d473bc6a1395026868 226 TIGRFAM TIGR02187 GlrX_arch: glutaredoxin-like domain protein 4 223 1.6E-89 T 23-10-2018 IPR011903 Glutaredoxin-like domain A0127_09800 e93b6b1332c843d473bc6a1395026868 226 Gene3D G3DSA:3.40.30.10 121 225 2.4E-25 T 23-10-2018 A0127_09800 e93b6b1332c843d473bc6a1395026868 226 SUPERFAMILY SSF52833 124 222 4.15E-20 T 23-10-2018 IPR036249 Thioredoxin-like superfamily A0127_09800 e93b6b1332c843d473bc6a1395026868 226 SUPERFAMILY SSF52833 5 117 2.45E-26 T 23-10-2018 IPR036249 Thioredoxin-like superfamily A0127_09800 e93b6b1332c843d473bc6a1395026868 226 Gene3D G3DSA:3.40.30.10 1 117 7.0E-39 T 23-10-2018 A0127_09800 e93b6b1332c843d473bc6a1395026868 226 Pfam PF13192 Thioredoxin domain 137 222 4.2E-14 T 23-10-2018 IPR012336 Thioredoxin-like fold A0127_04065 bacb161b4ee5cc9ffffce8ec2a4d03e2 300 ProSitePatterns PS00911 Dihydroorotate dehydrogenase signature 1. 40 59 - T 23-10-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 A0127_04065 bacb161b4ee5cc9ffffce8ec2a4d03e2 300 TIGRFAM TIGR01037 pyrD_sub1_fam: dihydroorotate dehydrogenase family protein 4 298 1.0E-129 T 23-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 A0127_04065 bacb161b4ee5cc9ffffce8ec2a4d03e2 300 Hamap MF_00224 Dihydroorotate dehydrogenase [pyrD]. 4 298 37.189 T 23-10-2018 IPR024920 Dihydroorotate dehydrogenase, class 1 GO:0004152|GO:0005737|GO:0006221 A0127_04065 bacb161b4ee5cc9ffffce8ec2a4d03e2 300 Gene3D G3DSA:3.20.20.70 12 289 1.2E-94 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A0127_04065 bacb161b4ee5cc9ffffce8ec2a4d03e2 300 SUPERFAMILY SSF51395 3 298 5.0E-85 T 23-10-2018 A0127_04065 bacb161b4ee5cc9ffffce8ec2a4d03e2 300 PIRSF PIRSF000164 1 300 2.4E-89 T 23-10-2018 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 A0127_04065 bacb161b4ee5cc9ffffce8ec2a4d03e2 300 Pfam PF01180 Dihydroorotate dehydrogenase 4 283 1.2E-63 T 23-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 A0127_04065 bacb161b4ee5cc9ffffce8ec2a4d03e2 300 Gene3D G3DSA:2.30.26.10 55 212 1.2E-94 T 23-10-2018 IPR023359 Dihydroorotate dehydrogenase A, chain A, domain 2 A0127_04065 bacb161b4ee5cc9ffffce8ec2a4d03e2 300 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 235 255 - T 23-10-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 A0127_05255 8b6e5d716dcfc74289b09ed82120d775 72 Gene3D G3DSA:2.40.50.140 6 71 2.0E-26 T 23-10-2018 A0127_05255 8b6e5d716dcfc74289b09ed82120d775 72 Pfam PF01938 TRAM domain 15 71 9.8E-15 T 23-10-2018 IPR002792 TRAM domain A0127_05255 8b6e5d716dcfc74289b09ed82120d775 72 SUPERFAMILY SSF50249 11 72 1.89E-17 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A0127_09370 75792a538d6eac2ff1942200d2a9663c 488 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 77 102 3.9E-26 T 23-10-2018 A0127_09370 75792a538d6eac2ff1942200d2a9663c 488 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 242 268 3.9E-26 T 23-10-2018 A0127_09370 75792a538d6eac2ff1942200d2a9663c 488 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 220 241 3.9E-26 T 23-10-2018 A0127_09370 75792a538d6eac2ff1942200d2a9663c 488 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 158 179 3.9E-26 T 23-10-2018 A0127_09370 75792a538d6eac2ff1942200d2a9663c 488 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 112 132 3.9E-26 T 23-10-2018 A0127_09370 75792a538d6eac2ff1942200d2a9663c 488 Pfam PF00361 Proton-conducting membrane transporter 137 417 2.8E-43 T 23-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A0127_06515 8fa08d05b56a45ef35ed23b5c7d9f1e4 379 Gene3D G3DSA:3.40.50.2000 196 357 2.6E-30 T 23-10-2018 A0127_06515 8fa08d05b56a45ef35ed23b5c7d9f1e4 379 SUPERFAMILY SSF53756 12 371 2.75E-63 T 23-10-2018 A0127_06515 8fa08d05b56a45ef35ed23b5c7d9f1e4 379 Pfam PF13439 Glycosyltransferase Family 4 14 187 4.0E-22 T 23-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 A0127_06515 8fa08d05b56a45ef35ed23b5c7d9f1e4 379 Gene3D G3DSA:3.40.50.2000 1 195 3.1E-24 T 23-10-2018 A0127_06515 8fa08d05b56a45ef35ed23b5c7d9f1e4 379 Pfam PF00534 Glycosyl transferases group 1 191 344 2.2E-25 T 23-10-2018 IPR001296 Glycosyl transferase, family 1 A0127_03180 667ae6767f47d816a64eea3c6d718064 741 Gene3D G3DSA:2.40.50.140 218 305 2.6E-8 T 23-10-2018 A0127_03180 667ae6767f47d816a64eea3c6d718064 741 SMART SM00316 131 196 1.1E-14 T 23-10-2018 IPR022967 RNA-binding domain, S1 A0127_03180 667ae6767f47d816a64eea3c6d718064 741 SUPERFAMILY SSF50249 225 296 1.22E-11 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A0127_03180 667ae6767f47d816a64eea3c6d718064 741 SUPERFAMILY SSF57938 5 32 7.19E-5 T 23-10-2018 IPR036410 Heat shock protein DnaJ, cysteine-rich domain superfamily A0127_03180 667ae6767f47d816a64eea3c6d718064 741 SUPERFAMILY SSF64182 337 734 6.15E-42 T 23-10-2018 IPR038763 DHH phosphoesterase superfamily A0127_03180 667ae6767f47d816a64eea3c6d718064 741 Gene3D G3DSA:2.40.50.140 128 202 4.2E-14 T 23-10-2018 A0127_03180 667ae6767f47d816a64eea3c6d718064 741 Gene3D G3DSA:3.90.1640.30 333 532 9.6E-9 T 23-10-2018 A0127_03180 667ae6767f47d816a64eea3c6d718064 741 Gene3D G3DSA:2.10.230.10 1 88 2.8E-6 T 23-10-2018 A0127_03180 667ae6767f47d816a64eea3c6d718064 741 Pfam PF01336 OB-fold nucleic acid binding domain 227 296 5.9E-11 T 23-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 A0127_03180 667ae6767f47d816a64eea3c6d718064 741 SUPERFAMILY SSF50249 121 194 1.12E-12 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A0127_03180 667ae6767f47d816a64eea3c6d718064 741 Pfam PF00575 S1 RNA binding domain 130 193 2.0E-9 T 23-10-2018 IPR003029 S1 domain GO:0003676 A0127_01575 10098d64a831b1b0a68b819d51ee487e 348 Gene3D G3DSA:3.50.50.60 149 259 1.3E-16 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A0127_01575 10098d64a831b1b0a68b819d51ee487e 348 PRINTS PR00419 Adrenodoxin reductase family signature 16 38 2.6E-14 T 23-10-2018 A0127_01575 10098d64a831b1b0a68b819d51ee487e 348 PRINTS PR00419 Adrenodoxin reductase family signature 39 52 2.6E-14 T 23-10-2018 A0127_01575 10098d64a831b1b0a68b819d51ee487e 348 PRINTS PR00419 Adrenodoxin reductase family signature 169 183 2.6E-14 T 23-10-2018 A0127_01575 10098d64a831b1b0a68b819d51ee487e 348 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 15 311 9.0E-29 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A0127_01575 10098d64a831b1b0a68b819d51ee487e 348 SUPERFAMILY SSF51971 14 270 3.59E-55 T 23-10-2018 A0127_01575 10098d64a831b1b0a68b819d51ee487e 348 Gene3D G3DSA:3.50.50.60 14 148 2.9E-24 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A0127_07915 dd35c92023f55f62a6673df6be275500 441 Gene3D G3DSA:3.40.50.1100 10 417 7.3E-176 T 23-10-2018 A0127_07915 dd35c92023f55f62a6673df6be275500 441 TIGRFAM TIGR01415 trpB_rel: pyridoxal-phosphate dependent TrpB-like enzyme 10 427 6.1E-218 T 23-10-2018 IPR006316 Tryptophan synthase, beta chain-like GO:0000162|GO:0004834|GO:0030170 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A0127_07915 dd35c92023f55f62a6673df6be275500 441 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 103 117 - T 23-10-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A0127_07915 dd35c92023f55f62a6673df6be275500 441 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 75 411 7.5E-44 T 23-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme A0127_07915 dd35c92023f55f62a6673df6be275500 441 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 18 424 42.628 T 23-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A0127_07915 dd35c92023f55f62a6673df6be275500 441 Gene3D G3DSA:3.40.50.1100 11 236 7.3E-176 T 23-10-2018 A0127_07915 dd35c92023f55f62a6673df6be275500 441 PIRSF PIRSF500824 1 433 5.3E-212 T 23-10-2018 IPR006316 Tryptophan synthase, beta chain-like GO:0000162|GO:0004834|GO:0030170 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A0127_07915 dd35c92023f55f62a6673df6be275500 441 SUPERFAMILY SSF53686 24 423 2.1E-110 T 23-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme A0127_07915 dd35c92023f55f62a6673df6be275500 441 PIRSF PIRSF001413 6 430 4.2E-157 T 23-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 A0127_02275 78eaf3dc1b1f5f6f65871101a73d6067 641 SMART SM00382 445 624 6.8E-13 T 23-10-2018 IPR003593 AAA+ ATPase domain A0127_02275 78eaf3dc1b1f5f6f65871101a73d6067 641 Gene3D G3DSA:3.40.50.300 414 641 4.2E-39 T 23-10-2018 A0127_02275 78eaf3dc1b1f5f6f65871101a73d6067 641 SUPERFAMILY SSF52540 420 625 1.22E-34 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_02275 78eaf3dc1b1f5f6f65871101a73d6067 641 Pfam PF00583 Acetyltransferase (GNAT) family 275 339 2.6E-4 T 23-10-2018 IPR000182 GNAT domain A0127_02275 78eaf3dc1b1f5f6f65871101a73d6067 641 Gene3D G3DSA:3.40.630.30 230 349 4.0E-8 T 23-10-2018 A0127_02275 78eaf3dc1b1f5f6f65871101a73d6067 641 Pfam PF00005 ABC transporter 436 572 2.4E-18 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A0127_02275 78eaf3dc1b1f5f6f65871101a73d6067 641 SUPERFAMILY SSF55729 275 365 3.85E-8 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase A0127_00710 fe396edba87becde26f80a75013d66d0 188 SUPERFAMILY SSF56300 20 175 9.28E-21 T 23-10-2018 A0127_00710 fe396edba87becde26f80a75013d66d0 188 Pfam PF00149 Calcineurin-like phosphoesterase 21 158 5.3E-7 T 23-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 A0127_00710 fe396edba87becde26f80a75013d66d0 188 Gene3D G3DSA:3.60.21.10 3 124 6.8E-9 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like A0127_07965 cf93fe67a2e48fab130993deb702e4bf 421 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 99 112 - T 23-10-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A0127_07965 cf93fe67a2e48fab130993deb702e4bf 421 Gene3D G3DSA:3.40.50.10860 36 180 5.2E-67 T 23-10-2018 A0127_07965 cf93fe67a2e48fab130993deb702e4bf 421 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 91 105 4.4E-29 T 23-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A0127_07965 cf93fe67a2e48fab130993deb702e4bf 421 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 216 236 4.4E-29 T 23-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A0127_07965 cf93fe67a2e48fab130993deb702e4bf 421 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 173 195 4.4E-29 T 23-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A0127_07965 cf93fe67a2e48fab130993deb702e4bf 421 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 345 356 4.4E-29 T 23-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A0127_07965 cf93fe67a2e48fab130993deb702e4bf 421 SUPERFAMILY SSF51735 182 419 2.58E-78 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A0127_07965 cf93fe67a2e48fab130993deb702e4bf 421 PIRSF PIRSF000185 1 420 1.5E-168 T 23-10-2018 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 A0127_07965 cf93fe67a2e48fab130993deb702e4bf 421 Gene3D G3DSA:3.40.50.720 182 420 9.6E-94 T 23-10-2018 A0127_07965 cf93fe67a2e48fab130993deb702e4bf 421 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 34 161 8.2E-54 T 23-10-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A0127_07965 cf93fe67a2e48fab130993deb702e4bf 421 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 182 417 5.1E-74 T 23-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A0127_07965 cf93fe67a2e48fab130993deb702e4bf 421 SMART SM00839 184 417 8.0E-95 T 23-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 A0127_07965 cf93fe67a2e48fab130993deb702e4bf 421 SUPERFAMILY SSF53223 4 184 9.6E-68 T 23-10-2018 A0127_02075 ffa224691ba29b629ba8a441b6721c1b 241 Gene3D G3DSA:1.20.1440.150 1 124 3.4E-60 T 23-10-2018 A0127_02075 ffa224691ba29b629ba8a441b6721c1b 241 SUPERFAMILY SSF50249 134 224 1.37E-16 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A0127_02075 ffa224691ba29b629ba8a441b6721c1b 241 Pfam PF01588 Putative tRNA binding domain 138 224 1.3E-18 T 23-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 A0127_02075 ffa224691ba29b629ba8a441b6721c1b 241 Gene3D G3DSA:2.40.50.140 125 241 1.0E-35 T 23-10-2018 A0127_07500 3f84ec0d4da58658399e4dc9f1ed46ba 209 SUPERFAMILY SSF54821 86 186 3.53E-26 T 23-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_07500 3f84ec0d4da58658399e4dc9f1ed46ba 209 Pfam PF07650 KH domain 17 88 1.7E-15 T 23-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_07500 3f84ec0d4da58658399e4dc9f1ed46ba 209 SMART SM00322 38 104 2.7E-8 T 23-10-2018 IPR004087 K Homology domain GO:0003676 A0127_07500 3f84ec0d4da58658399e4dc9f1ed46ba 209 Hamap MF_01309_A 30S ribosomal protein S3 [rpsC]. 2 197 42.868 T 23-10-2018 IPR027488 Ribosomal protein S3, archaeal GO:0003735|GO:0006412|GO:0015935 A0127_07500 3f84ec0d4da58658399e4dc9f1ed46ba 209 Gene3D G3DSA:3.30.300.20 1 86 1.4E-30 T 23-10-2018 IPR015946 K homology domain-like, alpha/beta A0127_07500 3f84ec0d4da58658399e4dc9f1ed46ba 209 SUPERFAMILY SSF54814 7 93 6.8E-26 T 23-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 A0127_07500 3f84ec0d4da58658399e4dc9f1ed46ba 209 Gene3D G3DSA:3.30.1140.32 87 209 7.0E-42 T 23-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_07500 3f84ec0d4da58658399e4dc9f1ed46ba 209 TIGRFAM TIGR01008 uS3_euk_arch: ribosomal protein uS3 3 197 4.6E-95 T 23-10-2018 IPR005703 Ribosomal protein S3, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_07500 3f84ec0d4da58658399e4dc9f1ed46ba 209 Pfam PF00189 Ribosomal protein S3, C-terminal domain 99 182 3.2E-24 T 23-10-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_02680 265cb050d9e83a27a5a55107e76dfb36 252 PIRSF PIRSF005902 1 252 4.2E-58 T 23-10-2018 IPR001130 TatD family GO:0016788 A0127_02680 265cb050d9e83a27a5a55107e76dfb36 252 SUPERFAMILY SSF51556 1 250 9.4E-57 T 23-10-2018 IPR032466 Metal-dependent hydrolase A0127_02680 265cb050d9e83a27a5a55107e76dfb36 252 Pfam PF01026 TatD related DNase 2 248 8.2E-57 T 23-10-2018 IPR001130 TatD family GO:0016788 A0127_02680 265cb050d9e83a27a5a55107e76dfb36 252 TIGRFAM TIGR00010 TIGR00010: hydrolase, TatD family 1 249 4.4E-69 T 23-10-2018 IPR015991 Uncharacterised hydrolase TatD-type GO:0004536 A0127_02680 265cb050d9e83a27a5a55107e76dfb36 252 Gene3D G3DSA:3.20.20.140 1 251 3.5E-63 T 23-10-2018 A0127_02680 265cb050d9e83a27a5a55107e76dfb36 252 ProSitePatterns PS01091 TatD deoxyribonuclease family signature 3. 187 203 - T 23-10-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 A0127_04780 5c30180518460e5083237f69c76b974f 223 TIGRFAM TIGR00659 TIGR00659: TIGR00659 family protein 6 222 2.1E-81 T 23-10-2018 IPR005261 Conserved hypothetical protein CHP00659 A0127_04780 5c30180518460e5083237f69c76b974f 223 Pfam PF04172 LrgB-like family 9 221 8.0E-74 T 23-10-2018 IPR007300 CidB/LrgB family A0127_03025 02ce04a25bcf076f0856aa89feaa7dea 486 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 14 484 80.398 T 23-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 A0127_03025 02ce04a25bcf076f0856aa89feaa7dea 486 SUPERFAMILY SSF51412 10 475 6.15E-113 T 23-10-2018 A0127_03025 02ce04a25bcf076f0856aa89feaa7dea 486 Gene3D G3DSA:3.20.20.70 4 484 4.8E-199 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A0127_03025 02ce04a25bcf076f0856aa89feaa7dea 486 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 14 471 1.7E-148 T 23-10-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 A0127_03025 02ce04a25bcf076f0856aa89feaa7dea 486 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 14 453 8.3E-192 T 23-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 A0127_03025 02ce04a25bcf076f0856aa89feaa7dea 486 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 292 304 - T 23-10-2018 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 A0127_03025 02ce04a25bcf076f0856aa89feaa7dea 486 SMART SM01240 13 471 2.6E-266 T 23-10-2018 A0127_03025 02ce04a25bcf076f0856aa89feaa7dea 486 PIRSF PIRSF000130 3 486 2.7E-196 T 23-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 A0127_03025 02ce04a25bcf076f0856aa89feaa7dea 486 Pfam PF00571 CBS domain 153 206 1.0E-15 T 23-10-2018 IPR000644 CBS domain A0127_03025 02ce04a25bcf076f0856aa89feaa7dea 486 Pfam PF00571 CBS domain 101 147 1.1E-13 T 23-10-2018 IPR000644 CBS domain A0127_03025 02ce04a25bcf076f0856aa89feaa7dea 486 SUPERFAMILY SSF54631 71 205 2.5E-33 T 23-10-2018 A0127_03025 02ce04a25bcf076f0856aa89feaa7dea 486 SMART SM00116 160 208 6.3E-16 T 23-10-2018 IPR000644 CBS domain A0127_03025 02ce04a25bcf076f0856aa89feaa7dea 486 SMART SM00116 102 150 2.5E-11 T 23-10-2018 IPR000644 CBS domain A0127_03365 1b9b9d3bd0197146e570a454a4f4a764 153 Pfam PF01850 PIN domain 3 125 3.0E-12 T 23-10-2018 IPR002716 PIN domain A0127_03365 1b9b9d3bd0197146e570a454a4f4a764 153 SUPERFAMILY SSF88723 1 133 6.73E-15 T 23-10-2018 IPR029060 PIN-like domain superfamily A0127_03365 1b9b9d3bd0197146e570a454a4f4a764 153 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 2 132 9.914 T 23-10-2018 IPR022907 VapC family GO:0004540 A0127_03365 1b9b9d3bd0197146e570a454a4f4a764 153 Gene3D G3DSA:3.40.50.1010 1 130 2.8E-9 T 23-10-2018 A0127_00950 0751056f7d23b05b8b9ad0e8fd6ff175 117 Gene3D G3DSA:3.30.310.70 2 117 1.2E-25 T 23-10-2018 IPR035923 TT1751-like domain superfamily A0127_00950 0751056f7d23b05b8b9ad0e8fd6ff175 117 SUPERFAMILY SSF103247 4 115 1.7E-26 T 23-10-2018 IPR035923 TT1751-like domain superfamily A0127_00950 0751056f7d23b05b8b9ad0e8fd6ff175 117 PIRSF PIRSF021774 1 116 9.0E-25 T 23-10-2018 IPR016796 Uncharacterised conserved protein UCP021774 A0127_00950 0751056f7d23b05b8b9ad0e8fd6ff175 117 Pfam PF03625 Domain of unknown function DUF302 39 94 1.6E-17 T 23-10-2018 IPR005180 Domain of unknown function DUF302 A0127_01800 38409b2246591a53fa87e0be0451242e 397 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 92 110 2.0E-31 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A0127_01800 38409b2246591a53fa87e0be0451242e 397 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 24 42 2.0E-31 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A0127_01800 38409b2246591a53fa87e0be0451242e 397 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 3 23 2.0E-31 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A0127_01800 38409b2246591a53fa87e0be0451242e 397 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 75 90 2.0E-31 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A0127_01800 38409b2246591a53fa87e0be0451242e 397 Pfam PF02824 TGS domain 345 393 5.3E-13 T 23-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 A0127_01800 38409b2246591a53fa87e0be0451242e 397 SUPERFAMILY SSF81271 322 393 4.97E-18 T 23-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 A0127_01800 38409b2246591a53fa87e0be0451242e 397 Pfam PF08438 GTPase of unknown function C-terminal 220 327 2.2E-36 T 23-10-2018 IPR013646 Uncharacterised GTP-binding protein, C-terminal A0127_01800 38409b2246591a53fa87e0be0451242e 397 Pfam PF01926 50S ribosome-binding GTPase 2 132 2.7E-20 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A0127_01800 38409b2246591a53fa87e0be0451242e 397 Gene3D G3DSA:3.10.20.30 319 397 1.4E-31 T 23-10-2018 IPR012675 Beta-grasp domain superfamily A0127_01800 38409b2246591a53fa87e0be0451242e 397 SUPERFAMILY SSF52540 1 315 2.31E-74 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_01800 38409b2246591a53fa87e0be0451242e 397 Gene3D G3DSA:1.10.8.470 126 215 7.5E-31 T 23-10-2018 A0127_04170 cb81429ad4b793dbb1eb5d56a0eef8d6 526 Gene3D G3DSA:2.30.30.300 170 213 1.2E-109 T 23-10-2018 IPR023386 Lysine-tRNA ligase, insertion domain superfamily GO:0004824 KEGG: 00970+6.1.1.6 A0127_04170 cb81429ad4b793dbb1eb5d56a0eef8d6 526 Gene3D G3DSA:1.10.10.860 271 318 5.8E-23 T 23-10-2018 A0127_04170 cb81429ad4b793dbb1eb5d56a0eef8d6 526 SUPERFAMILY SSF52374 3 319 2.95E-68 T 23-10-2018 A0127_04170 cb81429ad4b793dbb1eb5d56a0eef8d6 526 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 30 39 - T 23-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A0127_04170 cb81429ad4b793dbb1eb5d56a0eef8d6 526 Gene3D G3DSA:1.10.10.350 434 526 7.9E-26 T 23-10-2018 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 A0127_04170 cb81429ad4b793dbb1eb5d56a0eef8d6 526 Pfam PF01921 tRNA synthetases class I (K) 3 362 1.0E-138 T 23-10-2018 IPR002904 Lysine-tRNA ligase GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 A0127_04170 cb81429ad4b793dbb1eb5d56a0eef8d6 526 TIGRFAM TIGR00467 lysS_arch: lysine--tRNA ligase 2 524 1.3E-159 T 23-10-2018 IPR002904 Lysine-tRNA ligase GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 A0127_04170 cb81429ad4b793dbb1eb5d56a0eef8d6 526 SUPERFAMILY SSF48163 323 523 1.09E-50 T 23-10-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 A0127_04170 cb81429ad4b793dbb1eb5d56a0eef8d6 526 Hamap MF_00177 Lysine--tRNA ligase [lysS]. 2 526 37.961 T 23-10-2018 IPR002904 Lysine-tRNA ligase GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 A0127_04170 cb81429ad4b793dbb1eb5d56a0eef8d6 526 Gene3D G3DSA:1.10.10.770 319 433 3.5E-39 T 23-10-2018 A0127_04170 cb81429ad4b793dbb1eb5d56a0eef8d6 526 Gene3D G3DSA:3.40.50.620 4 270 1.2E-109 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A0127_10150 8cbe8de2d9066671ddaba3fd167084a5 109 Pfam PF01022 Bacterial regulatory protein, arsR family 53 74 2.0E-4 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A0127_10150 8cbe8de2d9066671ddaba3fd167084a5 109 SUPERFAMILY SSF46785 12 93 1.86E-11 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A0127_10150 8cbe8de2d9066671ddaba3fd167084a5 109 Gene3D G3DSA:1.10.10.10 8 95 4.1E-12 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A0127_00210 f1e327207682defc2a69c69117512609 156 TIGRFAM TIGR00372 cas4: CRISPR-associated protein Cas4 1 155 2.5E-29 T 23-10-2018 IPR013343 CRISPR-associated protein Cas4 A0127_00210 f1e327207682defc2a69c69117512609 156 Pfam PF01930 Domain of unknown function DUF83 1 155 5.1E-50 T 23-10-2018 IPR022765 Dna2/Cas4, domain of unknown function DUF83 A0127_00210 f1e327207682defc2a69c69117512609 156 Gene3D G3DSA:3.90.320.10 1 156 1.8E-6 T 23-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal A0127_01925 55d9d9a25115246177ce05823d456d97 180 Hamap MF_00796 Nucleoside-triphosphatase . 3 175 29.648 T 23-10-2018 IPR004948 Nucleoside-triphosphatase, THEP1 type GO:0098519 KEGG: 00230+3.6.1.15|KEGG: 00730+3.6.1.15|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210 A0127_01925 55d9d9a25115246177ce05823d456d97 180 Pfam PF03266 NTPase 4 167 1.1E-55 T 23-10-2018 IPR004948 Nucleoside-triphosphatase, THEP1 type GO:0098519 KEGG: 00230+3.6.1.15|KEGG: 00730+3.6.1.15|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210 A0127_01925 55d9d9a25115246177ce05823d456d97 180 SUPERFAMILY SSF52540 5 168 2.92E-23 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_01925 55d9d9a25115246177ce05823d456d97 180 Gene3D G3DSA:3.40.50.300 3 175 4.0E-42 T 23-10-2018 A0127_01925 55d9d9a25115246177ce05823d456d97 180 SMART SM00382 1 158 1.4E-4 T 23-10-2018 IPR003593 AAA+ ATPase domain A0127_04245 5b5d41037ccb38dabced5f0f4c91d9ea 307 Pfam PF06463 Molybdenum Cofactor Synthesis C 179 306 7.7E-21 T 23-10-2018 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A0127_04245 5b5d41037ccb38dabced5f0f4c91d9ea 307 Gene3D G3DSA:3.20.20.70 1 305 3.2E-77 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A0127_04245 5b5d41037ccb38dabced5f0f4c91d9ea 307 Hamap MF_01225_A GTP 3',8-cyclase [moaA]. 2 307 43.134 T 23-10-2018 IPR013485 Molybdenum cofactor biosynthesis protein A, archaea GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823 A0127_04245 5b5d41037ccb38dabced5f0f4c91d9ea 307 Pfam PF13353 4Fe-4S single cluster domain 17 104 4.8E-10 T 23-10-2018 A0127_04245 5b5d41037ccb38dabced5f0f4c91d9ea 307 SMART SM00729 11 227 2.2E-16 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A0127_04245 5b5d41037ccb38dabced5f0f4c91d9ea 307 TIGRFAM TIGR02668 moaA_archaeal: probable molybdenum cofactor biosynthesis protein A 2 307 3.0E-126 T 23-10-2018 IPR013485 Molybdenum cofactor biosynthesis protein A, archaea GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823 A0127_04245 5b5d41037ccb38dabced5f0f4c91d9ea 307 Pfam PF04055 Radical SAM superfamily 16 171 5.9E-34 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A0127_04245 5b5d41037ccb38dabced5f0f4c91d9ea 307 SUPERFAMILY SSF102114 3 300 9.94E-70 T 23-10-2018 A0127_06565 11b1173a18372df3f782cb88f1282e2e 287 SUPERFAMILY SSF51735 1 283 1.03E-86 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A0127_06565 11b1173a18372df3f782cb88f1282e2e 287 Gene3D G3DSA:3.40.50.720 3 271 7.7E-97 T 23-10-2018 A0127_06565 11b1173a18372df3f782cb88f1282e2e 287 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 112 140 - T 23-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A0127_06565 11b1173a18372df3f782cb88f1282e2e 287 Gene3D G3DSA:3.90.25.10 164 277 7.7E-97 T 23-10-2018 A0127_06565 11b1173a18372df3f782cb88f1282e2e 287 TIGRFAM TIGR01214 rmlD: dTDP-4-dehydrorhamnose reductase 2 283 5.4E-112 T 23-10-2018 IPR005913 dTDP-4-dehydrorhamnose reductase family Reactome: R-HSA-156581|Reactome: R-HSA-5689880 A0127_06565 11b1173a18372df3f782cb88f1282e2e 287 Pfam PF04321 RmlD substrate binding domain 1 283 1.4E-88 T 23-10-2018 IPR029903 RmlD-like substrate binding domain Reactome: R-HSA-156581|Reactome: R-HSA-5689880 A0127_01300 0d7313f1f8d61cba29a97abf10d566ec 169 Pfam PF01936 NYN domain 25 156 6.3E-21 T 23-10-2018 IPR021139 NYN domain, limkain-b1-type A0127_01300 0d7313f1f8d61cba29a97abf10d566ec 169 Gene3D G3DSA:3.40.50.1010 15 158 1.7E-11 T 23-10-2018 A0127_01300 0d7313f1f8d61cba29a97abf10d566ec 169 TIGRFAM TIGR00288 TIGR00288: TIGR00288 family protein 15 156 5.3E-63 T 23-10-2018 IPR002790 Conserved hypothetical protein CHP00288 A0127_01300 0d7313f1f8d61cba29a97abf10d566ec 169 ProDom PD010896 FAMILY DUF88 ARCHAEBACTERIAL PROTEIN MJ0482 PH0073 PF2040 VNG1608C MA3857 PF2039 24 97 2.0E-34 T 23-10-2018 A0127_01300 0d7313f1f8d61cba29a97abf10d566ec 169 SUPERFAMILY SSF53822 69 154 2.36E-5 T 23-10-2018 IPR028082 Periplasmic binding protein-like I A0127_05410 acb7bbecda780972e0803a51de5d989a 224 PIRSF PIRSF001357 1 223 3.5E-91 T 23-10-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 A0127_05410 acb7bbecda780972e0803a51de5d989a 224 Pfam PF01791 DeoC/LacD family aldolase 7 218 2.4E-23 T 23-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 A0127_05410 acb7bbecda780972e0803a51de5d989a 224 SUPERFAMILY SSF51569 3 220 4.81E-93 T 23-10-2018 A0127_05410 acb7bbecda780972e0803a51de5d989a 224 TIGRFAM TIGR00126 deoC: deoxyribose-phosphate aldolase 6 218 9.5E-91 T 23-10-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 A0127_05410 acb7bbecda780972e0803a51de5d989a 224 Hamap MF_00114 Deoxyribose-phosphate aldolase [deoC]. 4 222 39.216 T 23-10-2018 IPR028581 Deoxyribose-phosphate aldolase type I GO:0004139 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180 A0127_05410 acb7bbecda780972e0803a51de5d989a 224 Gene3D G3DSA:3.20.20.70 1 223 9.8E-107 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A0127_05410 acb7bbecda780972e0803a51de5d989a 224 SMART SM01133 5 220 4.3E-116 T 23-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 A0127_05240 b06542f94d74836a69887c681bb06c5e 549 Pfam PF00149 Calcineurin-like phosphoesterase 320 497 3.8E-14 T 23-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 A0127_05240 b06542f94d74836a69887c681bb06c5e 549 Gene3D G3DSA:3.60.21.10 325 542 4.2E-21 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like A0127_05240 b06542f94d74836a69887c681bb06c5e 549 SUPERFAMILY SSF56300 324 542 7.74E-37 T 23-10-2018 A0127_06860 7f565501e58e1b7fbd4c6456124b1b78 424 PRINTS PR00723 Subtilisin serine protease family (S8) signature 132 151 7.3E-20 T 23-10-2018 IPR015500 Peptidase S8, subtilisin-related A0127_06860 7f565501e58e1b7fbd4c6456124b1b78 424 PRINTS PR00723 Subtilisin serine protease family (S8) signature 347 363 7.3E-20 T 23-10-2018 IPR015500 Peptidase S8, subtilisin-related A0127_06860 7f565501e58e1b7fbd4c6456124b1b78 424 PRINTS PR00723 Subtilisin serine protease family (S8) signature 175 188 7.3E-20 T 23-10-2018 IPR015500 Peptidase S8, subtilisin-related A0127_06860 7f565501e58e1b7fbd4c6456124b1b78 424 SUPERFAMILY SSF54897 43 90 1.11E-6 T 23-10-2018 A0127_06860 7f565501e58e1b7fbd4c6456124b1b78 424 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 348 358 - T 23-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site A0127_06860 7f565501e58e1b7fbd4c6456124b1b78 424 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 137 148 - T 23-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site A0127_06860 7f565501e58e1b7fbd4c6456124b1b78 424 Gene3D G3DSA:3.30.70.80 25 93 5.4E-35 T 23-10-2018 IPR037045 Peptidase S8 propeptide/proteinase inhibitor I9 superfamily Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 A0127_06860 7f565501e58e1b7fbd4c6456124b1b78 424 SUPERFAMILY SSF52743 108 421 3.27E-87 T 23-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 A0127_06860 7f565501e58e1b7fbd4c6456124b1b78 424 Pfam PF00082 Subtilase family 135 411 2.9E-49 T 23-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A0127_06860 7f565501e58e1b7fbd4c6456124b1b78 424 Gene3D G3DSA:3.40.50.200 105 423 2.5E-113 T 23-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 A0127_00840 e753383b10f7567ab0b980b8310890c2 154 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 6 127 8.3E-26 T 23-10-2018 IPR023485 Phosphotyrosine protein phosphatase I A0127_00840 e753383b10f7567ab0b980b8310890c2 154 Gene3D G3DSA:3.40.50.2300 4 136 5.2E-46 T 23-10-2018 A0127_00840 e753383b10f7567ab0b980b8310890c2 154 SUPERFAMILY SSF52788 6 128 3.01E-36 T 23-10-2018 IPR036196 Phosphotyrosine protein phosphatase I superfamily A0127_00840 e753383b10f7567ab0b980b8310890c2 154 SMART SM00226 4 130 2.0E-44 T 23-10-2018 IPR023485 Phosphotyrosine protein phosphatase I A0127_03800 e6ddd6e1690e997b680ed3e9a47c52b1 140 TIGRFAM TIGR00149 TIGR00149_YjbQ: secondary thiamine-phosphate synthase enzyme 4 131 4.9E-40 T 23-10-2018 IPR001602 Uncharacterised protein family UPF0047 A0127_03800 e6ddd6e1690e997b680ed3e9a47c52b1 140 SUPERFAMILY SSF111038 2 131 1.01E-40 T 23-10-2018 IPR035917 YjbQ-like superfamily A0127_03800 e6ddd6e1690e997b680ed3e9a47c52b1 140 Gene3D G3DSA:2.60.120.460 1 132 1.3E-48 T 23-10-2018 IPR035917 YjbQ-like superfamily A0127_03800 e6ddd6e1690e997b680ed3e9a47c52b1 140 PIRSF PIRSF004681 1 133 4.2E-39 T 23-10-2018 IPR001602 Uncharacterised protein family UPF0047 A0127_03800 e6ddd6e1690e997b680ed3e9a47c52b1 140 Pfam PF01894 Uncharacterised protein family UPF0047 17 130 5.4E-37 T 23-10-2018 IPR001602 Uncharacterised protein family UPF0047 A0127_03060 55bcb8ed9cf9e9d548c98d88bb5f28d4 322 TIGRFAM TIGR00524 eIF-2B_rel: eIF-2B alpha/beta/delta-related uncharacterized proteins 4 299 6.6E-99 T 23-10-2018 IPR011559 Initiation factor 2B alpha/beta/delta GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 A0127_03060 55bcb8ed9cf9e9d548c98d88bb5f28d4 322 TIGRFAM TIGR00511 ribulose_e2b2: ribose-1,5-bisphosphate isomerase, e2b2 family 6 312 2.4E-149 T 23-10-2018 IPR005250 Ribose-1,5-bisphosphate isomerase, e2b2 family MetaCyc: PWY-5532 A0127_03060 55bcb8ed9cf9e9d548c98d88bb5f28d4 322 Gene3D G3DSA:1.20.120.420 1 114 2.2E-48 T 23-10-2018 IPR027363 Methylthioribose-1-phosphate isomerase, N-terminal KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 A0127_03060 55bcb8ed9cf9e9d548c98d88bb5f28d4 322 Gene3D G3DSA:3.40.50.10470 115 310 8.4E-85 T 23-10-2018 A0127_03060 55bcb8ed9cf9e9d548c98d88bb5f28d4 322 Pfam PF01008 Initiation factor 2 subunit family 18 299 5.7E-93 T 23-10-2018 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 A0127_03060 55bcb8ed9cf9e9d548c98d88bb5f28d4 322 SUPERFAMILY SSF100950 4 311 1.61E-100 T 23-10-2018 IPR037171 NagB/RpiA transferase-like A0127_02960 a1095139caca74114f512b31771cc936 334 Gene3D G3DSA:3.90.650.10 166 332 9.3E-50 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A0127_02960 a1095139caca74114f512b31771cc936 334 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 2 321 1.9E-123 T 23-10-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A0127_02960 a1095139caca74114f512b31771cc936 334 SUPERFAMILY SSF56042 166 327 4.19E-42 T 23-10-2018 IPR036676 PurM-like, C-terminal domain superfamily A0127_02960 a1095139caca74114f512b31771cc936 334 Pfam PF02769 AIR synthase related protein, C-terminal domain 171 327 6.4E-23 T 23-10-2018 IPR010918 PurM-like, C-terminal domain A0127_02960 a1095139caca74114f512b31771cc936 334 Pfam PF00586 AIR synthase related protein, N-terminal domain 57 159 1.3E-19 T 23-10-2018 IPR016188 PurM-like, N-terminal domain A0127_02960 a1095139caca74114f512b31771cc936 334 SUPERFAMILY SSF55326 2 165 9.42E-41 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A0127_02960 a1095139caca74114f512b31771cc936 334 Gene3D G3DSA:3.30.1330.10 1 165 3.9E-53 T 23-10-2018 IPR036921 PurM-like, N-terminal domain superfamily A0127_02960 a1095139caca74114f512b31771cc936 334 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 2 330 37.93 T 23-10-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 A0127_07130 535da22839cf8e23af59b4403160a4bf 344 SUPERFAMILY SSF55205 4 216 2.35E-66 T 23-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 A0127_07130 535da22839cf8e23af59b4403160a4bf 344 Hamap MF_00200 RNA 3'-terminal phosphate cyclase [rtcA]. 3 338 40.484 T 23-10-2018 IPR017770 RNA 3'-terminal phosphate cyclase type 1 GO:0003963|GO:0006396 A0127_07130 535da22839cf8e23af59b4403160a4bf 344 PIRSF PIRSF005378 1 343 1.5E-113 T 23-10-2018 IPR000228 RNA 3'-terminal phosphate cyclase GO:0006396 A0127_07130 535da22839cf8e23af59b4403160a4bf 344 TIGRFAM TIGR03399 RNA_3prim_cycl: RNA 3'-phosphate cyclase 4 324 3.8E-130 T 23-10-2018 IPR017770 RNA 3'-terminal phosphate cyclase type 1 GO:0003963|GO:0006396 A0127_07130 535da22839cf8e23af59b4403160a4bf 344 ProSitePatterns PS01287 RNA 3'-terminal phosphate cyclase signature. 154 164 - T 23-10-2018 IPR020719 RNA 3'-terminal phosphate cyclase-like, conserved site A0127_07130 535da22839cf8e23af59b4403160a4bf 344 SUPERFAMILY SSF52913 182 278 1.83E-25 T 23-10-2018 IPR036553 RNA 3'-terminal phosphate cyclase, insert domain superfamily A0127_07130 535da22839cf8e23af59b4403160a4bf 344 Pfam PF01137 RNA 3'-terminal phosphate cyclase 10 326 9.3E-78 T 23-10-2018 IPR023797 RNA 3'-terminal phosphate cyclase domain A0127_07130 535da22839cf8e23af59b4403160a4bf 344 Gene3D G3DSA:3.30.360.20 182 276 5.1E-128 T 23-10-2018 IPR036553 RNA 3'-terminal phosphate cyclase, insert domain superfamily A0127_07130 535da22839cf8e23af59b4403160a4bf 344 Gene3D G3DSA:3.65.10.20 5 320 5.1E-128 T 23-10-2018 IPR037136 RNA 3'-terminal phosphate cyclase domain superfamily A0127_07130 535da22839cf8e23af59b4403160a4bf 344 Pfam PF05189 RNA 3'-terminal phosphate cyclase (RTC), insert domain 182 275 8.8E-24 T 23-10-2018 IPR013791 RNA 3'-terminal phosphate cyclase, insert domain A0127_05755 3bbb44c6a3235f4177ba4c1fa15867b0 127 Pfam PF04322 Protein of unknown function (DUF473) 1 116 1.7E-31 T 23-10-2018 IPR007417 Protein of unknown function DUF473 A0127_05755 3bbb44c6a3235f4177ba4c1fa15867b0 127 ProDom PD020987 PF0014 UNCHARACTERIZED AF1250 PH0127 MJ0105 MA4414 ARCHAEAL 1 104 3.0E-50 T 23-10-2018 IPR007417 Protein of unknown function DUF473 A0127_04060 f272e9593d8037087d92aaf13a4370f3 239 Hamap MF_01633 7-cyano-7-deazaguanine synthase [queC]. 2 231 45.355 T 23-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 A0127_04060 f272e9593d8037087d92aaf13a4370f3 239 SUPERFAMILY SSF52402 1 235 2.87E-50 T 23-10-2018 A0127_04060 f272e9593d8037087d92aaf13a4370f3 239 PIRSF PIRSF006293 1 238 4.6E-69 T 23-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 A0127_04060 f272e9593d8037087d92aaf13a4370f3 239 Pfam PF06508 Queuosine biosynthesis protein QueC 3 224 1.5E-62 T 23-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 A0127_04060 f272e9593d8037087d92aaf13a4370f3 239 Gene3D G3DSA:3.40.50.620 1 236 1.0E-59 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A0127_04060 f272e9593d8037087d92aaf13a4370f3 239 TIGRFAM TIGR00364 TIGR00364: queuosine biosynthesis protein QueC 4 218 8.7E-48 T 23-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 A0127_03505 738b88e531a839bbfc31a542f90a87b0 185 SUPERFAMILY SSF52540 1 183 5.55E-19 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_03505 738b88e531a839bbfc31a542f90a87b0 185 Gene3D G3DSA:3.40.50.300 2 183 4.0E-45 T 23-10-2018 A0127_03505 738b88e531a839bbfc31a542f90a87b0 185 Hamap MF_01111 UPF0200 protein . 2 182 31.725 T 23-10-2018 IPR022970 Nucleoside triphosphate hydrolase-related A0127_03505 738b88e531a839bbfc31a542f90a87b0 185 Pfam PF13207 AAA domain 6 136 5.7E-20 T 23-10-2018 A0127_01470 7033ad0fa6eb764ec76ae2149c82605c 290 SUPERFAMILY SSF52540 3 286 2.79E-32 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_01470 7033ad0fa6eb764ec76ae2149c82605c 290 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 100 111 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A0127_01470 7033ad0fa6eb764ec76ae2149c82605c 290 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 3 264 4.6E-19 T 23-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain A0127_01470 7033ad0fa6eb764ec76ae2149c82605c 290 Pfam PF12837 4Fe-4S binding domain 63 85 3.0E-6 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A0127_01470 7033ad0fa6eb764ec76ae2149c82605c 290 SUPERFAMILY SSF54862 53 119 2.93E-18 T 23-10-2018 A0127_01470 7033ad0fa6eb764ec76ae2149c82605c 290 Gene3D G3DSA:3.30.70.20 61 113 1.6E-9 T 23-10-2018 A0127_02020 7979e3748a07e689e8931276104b7ff1 396 Gene3D G3DSA:2.170.190.11 50 148 1.2E-107 T 23-10-2018 A0127_02020 7979e3748a07e689e8931276104b7ff1 396 SUPERFAMILY SSF53218 181 322 4.84E-33 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily A0127_02020 7979e3748a07e689e8931276104b7ff1 396 Pfam PF00994 Probable molybdopterin binding domain 186 315 7.7E-17 T 23-10-2018 IPR001453 MoaB/Mog domain A0127_02020 7979e3748a07e689e8931276104b7ff1 396 Pfam PF03453 MoeA N-terminal region (domain I and II) 9 173 2.4E-45 T 23-10-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A0127_02020 7979e3748a07e689e8931276104b7ff1 396 SUPERFAMILY SSF63882 7 181 1.24E-57 T 23-10-2018 IPR036135 MoeA, N-terminal and linker domain superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A0127_02020 7979e3748a07e689e8931276104b7ff1 396 Pfam PF03454 MoeA C-terminal region (domain IV) 329 395 2.2E-16 T 23-10-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A0127_02020 7979e3748a07e689e8931276104b7ff1 396 SUPERFAMILY SSF63867 327 396 1.31E-18 T 23-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A0127_02020 7979e3748a07e689e8931276104b7ff1 396 Gene3D G3DSA:3.90.105.10 27 181 1.2E-107 T 23-10-2018 A0127_02020 7979e3748a07e689e8931276104b7ff1 396 SMART SM00852 186 317 1.0E-25 T 23-10-2018 IPR001453 MoaB/Mog domain A0127_02020 7979e3748a07e689e8931276104b7ff1 396 Gene3D G3DSA:3.40.980.10 19 314 1.2E-107 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily A0127_02020 7979e3748a07e689e8931276104b7ff1 396 Gene3D G3DSA:2.40.340.10 320 396 1.4E-26 T 23-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A0127_02185 8bef45abeb029b347995667d34884b85 370 Gene3D G3DSA:3.40.1280.30 90 234 7.1E-9 T 23-10-2018 IPR038459 tRNA methyltransferase TRM10-type domain superfamily A0127_02185 8bef45abeb029b347995667d34884b85 370 Pfam PF04252 Predicted SAM-dependent RNA methyltransferase 167 215 7.4E-5 T 23-10-2018 IPR007364 RNA methyltransferase TK0422/Sfm1 GO:0008168 A0127_02185 8bef45abeb029b347995667d34884b85 370 PIRSF PIRSF018978 1 370 1.8E-190 T 23-10-2018 IPR016742 tRNA methyltransferase, archaea GO:0008175|GO:0030488 A0127_06770 5b4c8a39843938cb1cb2406073ab3a20 57 Hamap MF_00777 30S ribosomal protein S27ae [rps27ae]. 11 56 19.538 T 23-10-2018 IPR022845 Ribosomal protein S27ae A0127_06770 5b4c8a39843938cb1cb2406073ab3a20 57 SUPERFAMILY SSF57829 11 57 2.38E-21 T 23-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 A0127_06770 5b4c8a39843938cb1cb2406073ab3a20 57 SMART SM01402 11 53 1.5E-24 T 23-10-2018 IPR002906 Ribosomal protein S27a GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 A0127_06770 5b4c8a39843938cb1cb2406073ab3a20 57 Pfam PF01599 Ribosomal protein S27a 12 53 2.6E-22 T 23-10-2018 IPR002906 Ribosomal protein S27a GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 A0127_06770 5b4c8a39843938cb1cb2406073ab3a20 57 Gene3D G3DSA:2.20.25.660 1 56 3.5E-20 T 23-10-2018 IPR038582 S27a-like superfamily Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 A0127_09905 ae3db4fcb620b5794bfeb7aa49f9bc3a 147 Gene3D G3DSA:1.20.1260.10 2 144 1.1E-8 T 23-10-2018 IPR012347 Ferritin-like A0127_09905 ae3db4fcb620b5794bfeb7aa49f9bc3a 147 SUPERFAMILY SSF47240 5 141 2.1E-8 T 23-10-2018 IPR009078 Ferritin-like superfamily A0127_09905 ae3db4fcb620b5794bfeb7aa49f9bc3a 147 Pfam PF02915 Rubrerythrin 7 141 4.6E-6 T 23-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 A0127_05610 d22f0eb97263045fd9fc359e625861b6 142 Hamap MF_00771 UPF0310 protein . 1 142 27.206 T 23-10-2018 IPR022996 Uncharacterised protein family UPF0310 A0127_05610 d22f0eb97263045fd9fc359e625861b6 142 SUPERFAMILY SSF88697 1 141 1.91E-41 T 23-10-2018 IPR015947 PUA-like superfamily A0127_05610 d22f0eb97263045fd9fc359e625861b6 142 Pfam PF01878 EVE domain 2 140 1.4E-25 T 23-10-2018 IPR002740 EVE domain A0127_05610 d22f0eb97263045fd9fc359e625861b6 142 Gene3D G3DSA:3.10.590.10 1 142 6.0E-61 T 23-10-2018 A0127_05530 cab2ab5adcfcc9025db3c98f36eaed3e 171 Hamap MF_01117 CDP-archaeol synthase [carS]. 14 171 27.546 T 23-10-2018 IPR002726 CDP-archaeol synthase, archaea KEGG: 00564+2.7.7.67|MetaCyc: PWY-6349 A0127_05530 cab2ab5adcfcc9025db3c98f36eaed3e 171 Pfam PF01864 CDP-archaeol synthase 7 171 1.2E-57 T 23-10-2018 IPR032690 CDP-archaeol synthase KEGG: 00564+2.7.7.67|MetaCyc: PWY-6349 A0127_07975 685df5336d2cf540edacf6adaea03110 203 Gene3D G3DSA:3.60.20.10 3 203 1.9E-67 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A0127_07975 685df5336d2cf540edacf6adaea03110 203 SUPERFAMILY SSF56235 5 202 3.66E-63 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A0127_07975 685df5336d2cf540edacf6adaea03110 203 Pfam PF00227 Proteasome subunit 6 185 3.2E-53 T 23-10-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 A0127_07975 685df5336d2cf540edacf6adaea03110 203 ProSitePatterns PS00854 Proteasome beta-type subunits signature. 11 58 - T 23-10-2018 IPR016050 Proteasome beta-type subunit, conserved site GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 A0127_07975 685df5336d2cf540edacf6adaea03110 203 TIGRFAM TIGR03634 arc_protsome_B: proteasome endopeptidase complex, archaeal, beta subunit 7 190 8.5E-77 T 23-10-2018 IPR019983 Peptidase T1A, proteasome beta-subunit, archaeal GO:0004175|GO:0005839|GO:0051603 A0127_07975 685df5336d2cf540edacf6adaea03110 203 Hamap MF_02113_A Proteasome subunit beta [prcB]. 3 197 35.865 T 23-10-2018 IPR019983 Peptidase T1A, proteasome beta-subunit, archaeal GO:0004175|GO:0005839|GO:0051603 A0127_07975 685df5336d2cf540edacf6adaea03110 203 PRINTS PR00141 Proteasome component signature 15 30 8.8E-11 T 23-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 A0127_07975 685df5336d2cf540edacf6adaea03110 203 PRINTS PR00141 Proteasome component signature 146 157 8.8E-11 T 23-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 A0127_07975 685df5336d2cf540edacf6adaea03110 203 PRINTS PR00141 Proteasome component signature 135 146 8.8E-11 T 23-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 A0127_07975 685df5336d2cf540edacf6adaea03110 203 PRINTS PR00141 Proteasome component signature 171 182 8.8E-11 T 23-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 A0127_00835 46fe90869fa30c20c0408df9d5e0e7f3 621 SMART SM00790 4 203 1.0E-112 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 A0127_00835 46fe90869fa30c20c0408df9d5e0e7f3 621 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 7 200 2.9E-68 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 A0127_00835 46fe90869fa30c20c0408df9d5e0e7f3 621 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 218 598 2.8E-96 T 23-10-2018 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 A0127_00835 46fe90869fa30c20c0408df9d5e0e7f3 621 SUPERFAMILY SSF48310 207 601 5.23E-104 T 23-10-2018 IPR036021 Aldehyde ferredoxin oxidoreductase-like, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 A0127_00835 46fe90869fa30c20c0408df9d5e0e7f3 621 Gene3D G3DSA:3.60.9.10 1 206 1.6E-72 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily A0127_00835 46fe90869fa30c20c0408df9d5e0e7f3 621 Gene3D G3DSA:1.10.569.10 237 428 6.2E-90 T 23-10-2018 IPR013984 Aldehyde ferredoxin oxidoreductase, domain 2 A0127_00835 46fe90869fa30c20c0408df9d5e0e7f3 621 Gene3D G3DSA:1.10.599.10 235 598 6.2E-90 T 23-10-2018 IPR013985 Aldehyde ferredoxin oxidoreductase, domain 3 GO:0016625|GO:0051536|GO:0055114 KEGG: 00030+1.2.7.5 A0127_00835 46fe90869fa30c20c0408df9d5e0e7f3 621 SUPERFAMILY SSF56228 1 204 1.83E-66 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily A0127_10255 f8a8bfced2704ecc73d268dfbeaaac7b 308 Gene3D G3DSA:1.10.10.10 228 307 1.0E-11 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A0127_10255 f8a8bfced2704ecc73d268dfbeaaac7b 308 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 241 299 9.2E-8 T 23-10-2018 IPR002831 Transcription regulator TrmB, N-terminal A0127_10255 f8a8bfced2704ecc73d268dfbeaaac7b 308 SUPERFAMILY SSF46785 234 300 2.77E-14 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A0127_06640 fb4f41cddb22843a19bb985ad22a1694 339 SUPERFAMILY SSF53335 155 319 4.51E-35 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A0127_06640 fb4f41cddb22843a19bb985ad22a1694 339 Pfam PF05050 Methyltransferase FkbM domain 164 316 2.9E-15 T 23-10-2018 IPR006342 Methyltransferase FkbM A0127_06640 fb4f41cddb22843a19bb985ad22a1694 339 Gene3D G3DSA:3.40.50.150 157 320 9.4E-29 T 23-10-2018 A0127_06640 fb4f41cddb22843a19bb985ad22a1694 339 TIGRFAM TIGR01444 fkbM_fam: methyltransferase, FkbM family 162 301 1.3E-31 T 23-10-2018 IPR006342 Methyltransferase FkbM A0127_07845 0027449966e56824847f0459e37e5eef 225 TIGRFAM TIGR00035 asp_race: aspartate racemase 2 225 1.4E-50 T 23-10-2018 IPR004380 Aspartate racemase GO:0006520|GO:0016855 A0127_07845 0027449966e56824847f0459e37e5eef 225 SUPERFAMILY SSF53681 1 114 4.58E-26 T 23-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A0127_07845 0027449966e56824847f0459e37e5eef 225 SUPERFAMILY SSF53681 116 223 1.44E-26 T 23-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A0127_07845 0027449966e56824847f0459e37e5eef 225 Gene3D G3DSA:3.40.50.1860 102 210 4.3E-71 T 23-10-2018 A0127_07845 0027449966e56824847f0459e37e5eef 225 Gene3D G3DSA:3.40.50.1860 4 214 4.3E-71 T 23-10-2018 A0127_07845 0027449966e56824847f0459e37e5eef 225 Pfam PF01177 Asp/Glu/Hydantoin racemase 7 219 1.9E-50 T 23-10-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A0127_00635 34b4156d4261732f7ca20abf12243f90 387 Pfam PF13439 Glycosyltransferase Family 4 18 185 4.8E-27 T 23-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 A0127_00635 34b4156d4261732f7ca20abf12243f90 387 Gene3D G3DSA:3.40.50.2000 181 353 2.7E-90 T 23-10-2018 A0127_00635 34b4156d4261732f7ca20abf12243f90 387 SUPERFAMILY SSF53756 5 375 1.07E-96 T 23-10-2018 A0127_00635 34b4156d4261732f7ca20abf12243f90 387 Pfam PF00534 Glycosyl transferases group 1 192 351 3.5E-42 T 23-10-2018 IPR001296 Glycosyl transferase, family 1 A0127_00635 34b4156d4261732f7ca20abf12243f90 387 Gene3D G3DSA:3.40.50.2000 8 370 2.7E-90 T 23-10-2018 A0127_02415 f5b654d962cccfdcd4719b61835ee7cb 282 PIRSF PIRSF006593 1 282 2.3E-100 T 23-10-2018 IPR014444 Uncharacterised conserved protein UCP006593 A0127_02415 f5b654d962cccfdcd4719b61835ee7cb 282 SUPERFAMILY SSF111321 1 281 5.1E-81 T 23-10-2018 IPR036075 AF1104-like superfamily A0127_02415 f5b654d962cccfdcd4719b61835ee7cb 282 Gene3D G3DSA:3.40.50.10880 132 282 1.4E-60 T 23-10-2018 A0127_02415 f5b654d962cccfdcd4719b61835ee7cb 282 Gene3D G3DSA:1.10.285.20 68 131 3.1E-19 T 23-10-2018 A0127_02415 f5b654d962cccfdcd4719b61835ee7cb 282 Gene3D G3DSA:1.10.8.380 1 67 2.0E-26 T 23-10-2018 A0127_02415 f5b654d962cccfdcd4719b61835ee7cb 282 Pfam PF01937 Protein of unknown function DUF89 4 276 2.2E-55 T 23-10-2018 IPR002791 Domain of unknown function DUF89 A0127_09875 47598e63ce3efaada6505aa1323b2c06 605 Gene3D G3DSA:1.10.569.10 242 427 5.7E-161 T 23-10-2018 IPR013984 Aldehyde ferredoxin oxidoreductase, domain 2 A0127_09875 47598e63ce3efaada6505aa1323b2c06 605 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 6 205 1.1E-83 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 A0127_09875 47598e63ce3efaada6505aa1323b2c06 605 Gene3D G3DSA:3.60.9.10 1 211 2.9E-96 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily A0127_09875 47598e63ce3efaada6505aa1323b2c06 605 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 223 601 2.2E-144 T 23-10-2018 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 A0127_09875 47598e63ce3efaada6505aa1323b2c06 605 SUPERFAMILY SSF56228 1 209 4.32E-79 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily A0127_09875 47598e63ce3efaada6505aa1323b2c06 605 SUPERFAMILY SSF48310 211 604 2.49E-148 T 23-10-2018 IPR036021 Aldehyde ferredoxin oxidoreductase-like, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 A0127_09875 47598e63ce3efaada6505aa1323b2c06 605 SMART SM00790 4 207 2.5E-133 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 A0127_09875 47598e63ce3efaada6505aa1323b2c06 605 Gene3D G3DSA:1.10.599.10 240 601 5.7E-161 T 23-10-2018 IPR013985 Aldehyde ferredoxin oxidoreductase, domain 3 GO:0016625|GO:0051536|GO:0055114 KEGG: 00030+1.2.7.5 A0127_09220 df2a2a9ed8588ed2da9710d85502dd3c 246 Gene3D G3DSA:1.10.340.30 39 152 4.5E-65 T 23-10-2018 A0127_09220 df2a2a9ed8588ed2da9710d85502dd3c 246 Pfam PF00633 Helix-hairpin-helix motif 119 148 1.7E-6 T 23-10-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 A0127_09220 df2a2a9ed8588ed2da9710d85502dd3c 246 SUPERFAMILY SSF48150 25 228 5.81E-63 T 23-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 A0127_09220 df2a2a9ed8588ed2da9710d85502dd3c 246 SMART SM00525 207 227 7.3E-7 T 23-10-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 A0127_09220 df2a2a9ed8588ed2da9710d85502dd3c 246 Hamap MF_00942 Endonuclease III [nth]. 20 230 33.655 T 23-10-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 A0127_09220 df2a2a9ed8588ed2da9710d85502dd3c 246 PIRSF PIRSF001435 18 231 7.8E-42 T 23-10-2018 A0127_09220 df2a2a9ed8588ed2da9710d85502dd3c 246 SMART SM00478 56 206 1.7E-55 T 23-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 A0127_09220 df2a2a9ed8588ed2da9710d85502dd3c 246 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 52 189 1.5E-17 T 23-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 A0127_09220 df2a2a9ed8588ed2da9710d85502dd3c 246 Gene3D G3DSA:1.10.1670.10 36 224 4.5E-65 T 23-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 A0127_09220 df2a2a9ed8588ed2da9710d85502dd3c 246 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 208 224 - T 23-10-2018 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 A0127_09220 df2a2a9ed8588ed2da9710d85502dd3c 246 ProSitePatterns PS01155 Endonuclease III family signature. 122 151 - T 23-10-2018 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 A0127_07195 b0e6234d5e8fa2c7dcc4b272c362b91b 250 SMART SM00283 4 244 1.6E-5 T 23-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 A0127_07195 b0e6234d5e8fa2c7dcc4b272c362b91b 250 SUPERFAMILY SSF58104 25 239 6.8E-38 T 23-10-2018 A0127_07195 b0e6234d5e8fa2c7dcc4b272c362b91b 250 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 61 206 1.1E-27 T 23-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 A0127_07195 b0e6234d5e8fa2c7dcc4b272c362b91b 250 Gene3D G3DSA:1.10.287.950 2 249 1.5E-35 T 23-10-2018 A0127_07195 b0e6234d5e8fa2c7dcc4b272c362b91b 250 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 128 157 2.1E-15 T 23-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 A0127_07195 b0e6234d5e8fa2c7dcc4b272c362b91b 250 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 99 126 2.1E-15 T 23-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 A0127_04135 6db8888432278f45f54d324856707d17 391 SUPERFAMILY SSF103473 6 382 1.96E-57 T 23-10-2018 IPR036259 MFS transporter superfamily A0127_04135 6db8888432278f45f54d324856707d17 391 Gene3D G3DSA:1.20.1250.20 2 381 3.7E-51 T 23-10-2018 A0127_04135 6db8888432278f45f54d324856707d17 391 PRINTS PR01035 Tetracycline resistance protein signature 299 319 2.9E-6 T 23-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A0127_04135 6db8888432278f45f54d324856707d17 391 PRINTS PR01035 Tetracycline resistance protein signature 17 33 2.9E-6 T 23-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A0127_04135 6db8888432278f45f54d324856707d17 391 PRINTS PR01035 Tetracycline resistance protein signature 135 157 2.9E-6 T 23-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 A0127_04135 6db8888432278f45f54d324856707d17 391 Pfam PF07690 Major Facilitator Superfamily 13 322 1.6E-39 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A0127_08840 949b43b86409000e2298a9e6e58a7497 183 TIGRFAM TIGR01957 nuoB_fam: NADH-quinone oxidoreductase, B subunit 7 142 4.7E-46 T 23-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A0127_08840 949b43b86409000e2298a9e6e58a7497 183 Gene3D G3DSA:3.40.50.12280 2 163 7.3E-55 T 23-10-2018 A0127_08840 949b43b86409000e2298a9e6e58a7497 183 SUPERFAMILY SSF56770 6 155 2.49E-54 T 23-10-2018 A0127_08840 949b43b86409000e2298a9e6e58a7497 183 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 25 136 9.1E-20 T 23-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A0127_05395 39a301eb4e3cb6192ec868b3a88569fc 445 Pfam PF00202 Aminotransferase class-III 34 440 4.7E-117 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A0127_05395 39a301eb4e3cb6192ec868b3a88569fc 445 Gene3D G3DSA:3.40.640.10 72 340 4.2E-153 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A0127_05395 39a301eb4e3cb6192ec868b3a88569fc 445 PIRSF PIRSF000521 2 143 2.3E-9 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A0127_05395 39a301eb4e3cb6192ec868b3a88569fc 445 PIRSF PIRSF000521 135 443 3.1E-53 T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A0127_05395 39a301eb4e3cb6192ec868b3a88569fc 445 SUPERFAMILY SSF53383 33 441 3.66E-128 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A0127_05395 39a301eb4e3cb6192ec868b3a88569fc 445 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 260 297 - T 23-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 A0127_05395 39a301eb4e3cb6192ec868b3a88569fc 445 Gene3D G3DSA:3.90.1150.10 14 438 4.2E-153 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A0127_06340 4fe3dc897f450e74f6f33c085ec46cfc 1358 Pfam PF03065 Glycosyl hydrolase family 57 36 538 6.7E-128 T 23-10-2018 IPR004300 Glycoside hydrolase family 57, N-terminal domain GO:0003824|GO:0005975 A0127_06340 4fe3dc897f450e74f6f33c085ec46cfc 1358 SUPERFAMILY SSF49344 1037 1270 1.14E-77 T 23-10-2018 A0127_06340 4fe3dc897f450e74f6f33c085ec46cfc 1358 TIGRFAM TIGR04288 CGP_CTERM: CGP-CTERM domain 1338 1357 4.7E-8 T 23-10-2018 IPR027552 CGP-CTERM domain A0127_06340 4fe3dc897f450e74f6f33c085ec46cfc 1358 SUPERFAMILY SSF49344 793 1028 9.02E-81 T 23-10-2018 A0127_06340 4fe3dc897f450e74f6f33c085ec46cfc 1358 Gene3D G3DSA:2.60.40.1190 791 1031 6.7E-69 T 23-10-2018 A0127_06340 4fe3dc897f450e74f6f33c085ec46cfc 1358 Gene3D G3DSA:2.60.40.1190 1036 1273 1.7E-64 T 23-10-2018 A0127_06340 4fe3dc897f450e74f6f33c085ec46cfc 1358 Gene3D G3DSA:3.20.110.20 218 517 4.6E-25 T 23-10-2018 A0127_06340 4fe3dc897f450e74f6f33c085ec46cfc 1358 SUPERFAMILY SSF88713 32 577 2.97E-67 T 23-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 A0127_06340 4fe3dc897f450e74f6f33c085ec46cfc 1358 Pfam PF09985 C-terminal binding-module, SLH-like, of glucodextranase 794 1026 1.9E-80 T 23-10-2018 IPR019248 Glucodextranase-like, C-terminal A0127_06340 4fe3dc897f450e74f6f33c085ec46cfc 1358 Pfam PF09985 C-terminal binding-module, SLH-like, of glucodextranase 1038 1268 1.8E-77 T 23-10-2018 IPR019248 Glucodextranase-like, C-terminal A0127_06150 6f575e52a17fb658e705a761f0716854 514 Gene3D G3DSA:1.10.3720.10 300 508 2.0E-19 T 23-10-2018 IPR035906 MetI-like superfamily A0127_06150 6f575e52a17fb658e705a761f0716854 514 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 11 67 2.9E-6 T 23-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain A0127_06150 6f575e52a17fb658e705a761f0716854 514 SUPERFAMILY SSF161098 303 495 1.07E-21 T 23-10-2018 IPR035906 MetI-like superfamily A0127_06150 6f575e52a17fb658e705a761f0716854 514 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 325 512 2.9E-29 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A0127_01900 bed9683630c4944b73a41ae1ebbb9b9f 113 SUPERFAMILY SSF88659 46 93 6.54E-9 T 23-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A0127_01900 bed9683630c4944b73a41ae1ebbb9b9f 113 Hamap MF_00674 UPF0251 protein . 12 109 24.099 T 23-10-2018 IPR002852 Uncharacterised protein family UPF0251 A0127_01900 bed9683630c4944b73a41ae1ebbb9b9f 113 Pfam PF02001 Protein of unknown function DUF134 11 105 2.5E-27 T 23-10-2018 IPR002852 Uncharacterised protein family UPF0251 A0127_01900 bed9683630c4944b73a41ae1ebbb9b9f 113 Gene3D G3DSA:1.10.10.10 45 94 2.3E-10 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A0127_02460 c64d55db068a1893759c4764d528bb94 381 SMART SM00981 74 168 4.0E-19 T 23-10-2018 IPR004114 THUMP domain GO:0003723 A0127_02460 c64d55db068a1893759c4764d528bb94 381 SUPERFAMILY SSF143437 2 176 4.36E-47 T 23-10-2018 A0127_02460 c64d55db068a1893759c4764d528bb94 381 Pfam PF02568 Thiamine biosynthesis protein (ThiI) 178 369 6.8E-66 T 23-10-2018 IPR020536 Thil, AANH domain GO:0004810 KEGG: 00730+2.8.1.4 A0127_02460 c64d55db068a1893759c4764d528bb94 381 Gene3D G3DSA:3.30.70.1510 2 84 1.6E-32 T 23-10-2018 A0127_02460 c64d55db068a1893759c4764d528bb94 381 Pfam PF02926 THUMP domain 29 168 1.3E-25 T 23-10-2018 IPR004114 THUMP domain GO:0003723 A0127_02460 c64d55db068a1893759c4764d528bb94 381 SUPERFAMILY SSF52402 178 337 1.08E-49 T 23-10-2018 A0127_02460 c64d55db068a1893759c4764d528bb94 381 Gene3D G3DSA:3.40.50.620 178 376 8.7E-66 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A0127_02460 c64d55db068a1893759c4764d528bb94 381 Gene3D G3DSA:3.30.2300.10 85 166 1.9E-29 T 23-10-2018 A0127_02460 c64d55db068a1893759c4764d528bb94 381 Hamap MF_00021 tRNA sulfurtransferase [thiI]. 1 381 126.683 T 23-10-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 KEGG: 00730+2.8.1.4 A0127_02460 c64d55db068a1893759c4764d528bb94 381 TIGRFAM TIGR00342 TIGR00342: tRNA sulfurtransferase ThiI 5 366 2.4E-104 T 23-10-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 KEGG: 00730+2.8.1.4 A0127_05775 22c40bed66b122393460f87d39cc453c 424 SUPERFAMILY SSF51338 1 423 8.28E-37 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A0127_05775 22c40bed66b122393460f87d39cc453c 424 Gene3D G3DSA:3.20.20.140 55 344 4.7E-156 T 23-10-2018 A0127_05775 22c40bed66b122393460f87d39cc453c 424 Gene3D G3DSA:2.30.40.10 4 416 4.7E-156 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A0127_05775 22c40bed66b122393460f87d39cc453c 424 Pfam PF01979 Amidohydrolase family 51 397 4.4E-80 T 23-10-2018 IPR006680 Amidohydrolase-related GO:0016787 A0127_05775 22c40bed66b122393460f87d39cc453c 424 Hamap MF_01281 5'-deoxyadenosine deaminase [dadD]. 2 424 48.46 T 23-10-2018 IPR023512 Deaminase MtaD/DadD GO:0019239 A0127_05775 22c40bed66b122393460f87d39cc453c 424 SUPERFAMILY SSF51556 54 347 3.24E-106 T 23-10-2018 IPR032466 Metal-dependent hydrolase A0127_01980 d5fb563371b5b061c7009369cc1e5079 405 Pfam PF01941 S-adenosylmethionine synthetase (AdoMet synthetase) 6 401 8.7E-180 T 23-10-2018 IPR027790 S-adenosylmethionine synthase KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912 A0127_01980 d5fb563371b5b061c7009369cc1e5079 405 Gene3D G3DSA:3.30.300.340 18 286 1.3E-172 T 23-10-2018 A0127_01980 d5fb563371b5b061c7009369cc1e5079 405 Hamap MF_00136 S-adenosylmethionine synthase [mat]. 5 405 52.169 T 23-10-2018 IPR002795 S-adenosylmethionine synthetase, archaea GO:0004478|GO:0005524|GO:0006730 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912 A0127_01980 d5fb563371b5b061c7009369cc1e5079 405 ProDom PD011777 SYNTHETASE TRANSFERASE METHIONINE ADENOSYLTRANSFERASE S-ADENOSYLMETHIONINE NUCLEOTIDE-BINDING METABOLISM ATP-BINDING MAGNESIUM ONE-CARBON 21 405 0.0 T 23-10-2018 A0127_01980 d5fb563371b5b061c7009369cc1e5079 405 Gene3D G3DSA:3.30.300.280 16 398 1.3E-172 T 23-10-2018 A0127_01980 d5fb563371b5b061c7009369cc1e5079 405 Gene3D G3DSA:3.30.300.10 30 154 1.3E-172 T 23-10-2018 A0127_04900 4abed95c4f301106c9e3d6d35c0e5a37 304 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 3 304 1.4E-40 T 23-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 A0127_04900 4abed95c4f301106c9e3d6d35c0e5a37 304 SUPERFAMILY SSF52283 1 133 4.54E-40 T 23-10-2018 A0127_04900 4abed95c4f301106c9e3d6d35c0e5a37 304 Gene3D G3DSA:3.40.50.720 7 298 3.0E-136 T 23-10-2018 A0127_04900 4abed95c4f301106c9e3d6d35c0e5a37 304 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 105 280 2.3E-72 T 23-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 A0127_04900 4abed95c4f301106c9e3d6d35c0e5a37 304 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 219 235 - T 23-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site A0127_04900 4abed95c4f301106c9e3d6d35c0e5a37 304 SUPERFAMILY SSF51735 99 281 6.04E-67 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A0127_04900 4abed95c4f301106c9e3d6d35c0e5a37 304 Gene3D G3DSA:3.40.50.720 92 282 3.0E-136 T 23-10-2018 A0127_04900 4abed95c4f301106c9e3d6d35c0e5a37 304 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 190 212 - T 23-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site A0127_04900 4abed95c4f301106c9e3d6d35c0e5a37 304 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 142 169 - T 23-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 A0127_05005 eeaf395261ab0d825447b73214b9c4c7 395 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 265 368 4.5E-34 T 23-10-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II A0127_05005 eeaf395261ab0d825447b73214b9c4c7 395 SUPERFAMILY SSF52518 7 253 1.05E-68 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold A0127_05005 eeaf395261ab0d825447b73214b9c4c7 395 Gene3D G3DSA:3.40.50.920 255 395 1.6E-45 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A0127_05005 eeaf395261ab0d825447b73214b9c4c7 395 Gene3D G3DSA:3.40.50.970 6 254 5.0E-98 T 23-10-2018 A0127_05005 eeaf395261ab0d825447b73214b9c4c7 395 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 19 241 4.1E-77 T 23-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 A0127_05005 eeaf395261ab0d825447b73214b9c4c7 395 SUPERFAMILY SSF52922 256 377 1.2E-36 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A0127_06945 84d22409e00872046f4695c16793ed45 328 SMART SM00870 2 314 2.2E-124 T 23-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 A0127_06945 84d22409e00872046f4695c16793ed45 328 TIGRFAM TIGR00519 asnASE_I: L-asparaginase, type I 2 326 1.6E-92 T 23-10-2018 IPR006033 L-asparaginase, type I GO:0004067|GO:0006520 Reactome: R-HSA-70614 A0127_06945 84d22409e00872046f4695c16793ed45 328 Pfam PF00710 Asparaginase, N-terminal 2 187 1.2E-59 T 23-10-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 A0127_06945 84d22409e00872046f4695c16793ed45 328 PIRSF PIRSF500176 1 323 2.5E-98 T 23-10-2018 A0127_06945 84d22409e00872046f4695c16793ed45 328 ProSitePatterns PS00917 Asparaginase / glutaminase active site signature 2. 78 88 - T 23-10-2018 IPR027475 Asparaginase/glutaminase, active site 2 Reactome: R-HSA-70614 A0127_06945 84d22409e00872046f4695c16793ed45 328 PRINTS PR00139 Asparaginase/glutaminase family signature 3 14 6.1E-14 T 23-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 A0127_06945 84d22409e00872046f4695c16793ed45 328 PRINTS PR00139 Asparaginase/glutaminase family signature 251 269 6.1E-14 T 23-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 A0127_06945 84d22409e00872046f4695c16793ed45 328 PRINTS PR00139 Asparaginase/glutaminase family signature 77 95 6.1E-14 T 23-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 A0127_06945 84d22409e00872046f4695c16793ed45 328 Gene3D G3DSA:3.40.50.40 201 327 1.4E-43 T 23-10-2018 IPR027473 L-asparaginase, C-terminal Reactome: R-HSA-70614 A0127_06945 84d22409e00872046f4695c16793ed45 328 ProSitePatterns PS00144 Asparaginase / glutaminase active site signature 1. 5 13 - T 23-10-2018 IPR020827 Asparaginase/glutaminase, active site 1 GO:0006520 A0127_06945 84d22409e00872046f4695c16793ed45 328 SUPERFAMILY SSF53774 2 326 1.27E-98 T 23-10-2018 IPR036152 Asparaginase/glutaminase-like superfamily Reactome: R-HSA-70614 A0127_06945 84d22409e00872046f4695c16793ed45 328 Gene3D G3DSA:3.40.50.1170 1 197 6.0E-69 T 23-10-2018 IPR037152 L-asparaginase, N-terminal domain superfamily Reactome: R-HSA-70614 A0127_06945 84d22409e00872046f4695c16793ed45 328 PIRSF PIRSF001220 1 325 1.3E-95 T 23-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 A0127_09995 0b1ca2298078121013400afdae8be7b2 420 PRINTS PR01988 Putative bacilysin exporter bacE signature 162 179 3.5E-8 T 23-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 A0127_09995 0b1ca2298078121013400afdae8be7b2 420 PRINTS PR01988 Putative bacilysin exporter bacE signature 293 316 3.5E-8 T 23-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 A0127_09995 0b1ca2298078121013400afdae8be7b2 420 PRINTS PR01988 Putative bacilysin exporter bacE signature 46 64 3.5E-8 T 23-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 A0127_09995 0b1ca2298078121013400afdae8be7b2 420 PRINTS PR01988 Putative bacilysin exporter bacE signature 72 90 3.5E-8 T 23-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 A0127_09995 0b1ca2298078121013400afdae8be7b2 420 PRINTS PR01988 Putative bacilysin exporter bacE signature 135 156 3.5E-8 T 23-10-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 A0127_09995 0b1ca2298078121013400afdae8be7b2 420 Gene3D G3DSA:1.20.1250.20 210 400 1.5E-13 T 23-10-2018 A0127_09995 0b1ca2298078121013400afdae8be7b2 420 TIGRFAM TIGR00900 2A0121: H+ Antiporter protein 7 373 8.0E-104 T 23-10-2018 IPR004751 Drug antiporter protein GO:0015307|GO:0015893 A0127_09995 0b1ca2298078121013400afdae8be7b2 420 Gene3D G3DSA:1.20.1250.20 2 184 1.9E-23 T 23-10-2018 A0127_09995 0b1ca2298078121013400afdae8be7b2 420 Pfam PF07690 Major Facilitator Superfamily 11 362 2.7E-33 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A0127_09995 0b1ca2298078121013400afdae8be7b2 420 SUPERFAMILY SSF103473 4 396 1.31E-43 T 23-10-2018 IPR036259 MFS transporter superfamily A0127_06210 8db563982dfced08bb528afab9c2bf23 346 SUPERFAMILY SSF56747 6 343 4.58E-95 T 23-10-2018 A0127_06210 8db563982dfced08bb528afab9c2bf23 346 Pfam PF01896 DNA primase small subunit 96 308 3.5E-14 T 23-10-2018 IPR002755 DNA primase, small subunit GO:0003896|GO:0006269 Reactome: R-HSA-113501|Reactome: R-HSA-174411|Reactome: R-HSA-174430|Reactome: R-HSA-68952|Reactome: R-HSA-68962|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183 A0127_06210 8db563982dfced08bb528afab9c2bf23 346 Hamap MF_00700 DNA primase small subunit PriS [priS]. 11 345 23.701 T 23-10-2018 IPR023639 DNA primase small subunit PriS GO:0003896 A0127_06210 8db563982dfced08bb528afab9c2bf23 346 Gene3D G3DSA:3.90.920.10 9 328 5.1E-125 T 23-10-2018 A0127_06210 8db563982dfced08bb528afab9c2bf23 346 TIGRFAM TIGR00335 primase_sml: putative DNA primase, eukaryotic-type, small subunit 12 331 8.5E-59 T 23-10-2018 IPR014052 DNA primase, small subunit, eukaryotic/archaeal GO:0003896|GO:0006269 Reactome: R-HSA-113501|Reactome: R-HSA-174411|Reactome: R-HSA-174430|Reactome: R-HSA-68952|Reactome: R-HSA-68962|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183 A0127_06210 8db563982dfced08bb528afab9c2bf23 346 Gene3D G3DSA:1.10.8.160 176 279 5.1E-125 T 23-10-2018 A0127_02620 38867807a414c80907a9bd1629c8733a 255 Gene3D G3DSA:3.20.20.370 1 255 6.3E-110 T 23-10-2018 A0127_02620 38867807a414c80907a9bd1629c8733a 255 Hamap MF_00691 UPF0271 protein YbgL [ybgL]. 1 245 46.545 T 23-10-2018 IPR005501 UPF0271 family, LamB/YcsF/PxpA KEGG: 00480+3.5.2.9|MetaCyc: PWY-4041|MetaCyc: PWY-7942 A0127_02620 38867807a414c80907a9bd1629c8733a 255 Pfam PF03746 LamB/YcsF family 3 241 2.0E-103 T 23-10-2018 IPR005501 UPF0271 family, LamB/YcsF/PxpA KEGG: 00480+3.5.2.9|MetaCyc: PWY-4041|MetaCyc: PWY-7942 A0127_02620 38867807a414c80907a9bd1629c8733a 255 SUPERFAMILY SSF88713 1 252 6.67E-103 T 23-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 A0127_00145 69ae5c86320db0bc08e51cd1637a07a4 94 SUPERFAMILY SSF117916 2 77 1.14E-10 T 23-10-2018 IPR034904 Fe-S cluster assembly domain superfamily A0127_00145 69ae5c86320db0bc08e51cd1637a07a4 94 Pfam PF01883 Iron-sulfur cluster assembly protein 4 45 5.0E-7 T 23-10-2018 IPR002744 MIP18 family-like A0127_00145 69ae5c86320db0bc08e51cd1637a07a4 94 Gene3D G3DSA:3.30.300.130 2 85 2.8E-9 T 23-10-2018 IPR034904 Fe-S cluster assembly domain superfamily A0127_07615 4caed6f3410ed6d42895eabd260081c2 83 Hamap MF_00721 50S ribosomal protein L14e [rpl14e]. 1 79 27.562 T 23-10-2018 IPR023651 Ribosomal protein L14e GO:0003735|GO:0005840|GO:0006412 A0127_07615 4caed6f3410ed6d42895eabd260081c2 83 SUPERFAMILY SSF50104 2 80 1.9E-19 T 23-10-2018 IPR008991 Translation protein SH3-like domain superfamily A0127_07615 4caed6f3410ed6d42895eabd260081c2 83 Gene3D G3DSA:2.30.30.30 2 83 2.0E-29 T 23-10-2018 IPR014722 Ribosomal protein L2, domain 2 A0127_00130 7cba2ee38b74e052daeda1333e95fdb9 134 SMART SM00670 1 124 4.9E-9 T 23-10-2018 IPR002716 PIN domain A0127_00130 7cba2ee38b74e052daeda1333e95fdb9 134 SUPERFAMILY SSF88723 1 132 6.45E-24 T 23-10-2018 IPR029060 PIN-like domain superfamily A0127_00130 7cba2ee38b74e052daeda1333e95fdb9 134 Gene3D G3DSA:3.40.50.1010 3 132 1.6E-20 T 23-10-2018 A0127_00130 7cba2ee38b74e052daeda1333e95fdb9 134 Pfam PF01850 PIN domain 4 126 9.0E-21 T 23-10-2018 IPR002716 PIN domain A0127_09320 9b8d7b5afb3705001ab8196d5e78df15 159 Pfam PF08984 Domain of unknown function (DUF1858) 89 144 7.1E-16 T 23-10-2018 IPR015077 Domain of unknown function DUF1858 A0127_09320 9b8d7b5afb3705001ab8196d5e78df15 159 Gene3D G3DSA:1.10.3910.10 84 154 1.5E-17 T 23-10-2018 IPR038062 ScdA-like, N-terminal domain superfamily A0127_09320 9b8d7b5afb3705001ab8196d5e78df15 159 Gene3D G3DSA:3.30.110.40 1 67 2.2E-7 T 23-10-2018 IPR036868 TusA-like domain superfamily A0127_09320 9b8d7b5afb3705001ab8196d5e78df15 159 SUPERFAMILY SSF140683 88 153 8.24E-16 T 23-10-2018 IPR038062 ScdA-like, N-terminal domain superfamily A0127_09320 9b8d7b5afb3705001ab8196d5e78df15 159 Pfam PF01206 Sulfurtransferase TusA 2 67 4.2E-10 T 23-10-2018 IPR001455 TusA-like domain A0127_09320 9b8d7b5afb3705001ab8196d5e78df15 159 SUPERFAMILY SSF64307 2 67 1.1E-11 T 23-10-2018 IPR036868 TusA-like domain superfamily A0127_01635 07a0e79400f2b943d2064bf474c2dea0 295 Pfam PF02653 Branched-chain amino acid transport system / permease component 13 275 9.7E-32 T 23-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 A0127_07830 b5ffe85a118153b3e31b98213164fe37 217 Pfam PF03192 Pyrococcus protein of unknown function, DUF257 11 213 6.4E-51 T 23-10-2018 IPR005489 Protein of unknown function DUF257 A0127_07830 b5ffe85a118153b3e31b98213164fe37 217 Gene3D G3DSA:3.40.50.11570 5 215 1.1E-57 T 23-10-2018 A0127_02605 0c68ffc29da3822aaa5b684f0ceb8a43 177 Pfam PF13238 AAA domain 3 116 1.9E-23 T 23-10-2018 A0127_02605 0c68ffc29da3822aaa5b684f0ceb8a43 177 Gene3D G3DSA:3.40.50.300 1 177 7.1E-61 T 23-10-2018 A0127_02605 0c68ffc29da3822aaa5b684f0ceb8a43 177 SUPERFAMILY SSF52540 1 153 1.01E-25 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_02605 0c68ffc29da3822aaa5b684f0ceb8a43 177 Hamap MF_00039 Putative adenylate kinase. 1 160 25.212 T 23-10-2018 IPR020618 Adenylate kinase isoenzyme 6 GO:0004017|GO:0005524 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 A0127_00350 9d507d13fa81abb917ca08a7960d2074 662 SUPERFAMILY SSF52540 6 173 5.64E-43 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_00350 9d507d13fa81abb917ca08a7960d2074 662 TIGRFAM TIGR00437 feoB: ferrous iron transport protein B 10 628 2.6E-185 T 23-10-2018 IPR003373 Ferrous iron transport protein B GO:0005525|GO:0015093|GO:0015684|GO:0016021 A0127_00350 9d507d13fa81abb917ca08a7960d2074 662 Gene3D G3DSA:3.40.50.300 1 170 9.9E-48 T 23-10-2018 A0127_00350 9d507d13fa81abb917ca08a7960d2074 662 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 6 26 1.1E-5 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A0127_00350 9d507d13fa81abb917ca08a7960d2074 662 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 27 45 1.1E-5 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A0127_00350 9d507d13fa81abb917ca08a7960d2074 662 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 3 156 5.7E-12 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A0127_00350 9d507d13fa81abb917ca08a7960d2074 662 Pfam PF07664 Ferrous iron transport protein B C terminus 460 512 9.9E-20 T 23-10-2018 IPR011640 Ferrous iron transport protein B, C-terminal GO:0015093|GO:0015684|GO:0016021 A0127_00350 9d507d13fa81abb917ca08a7960d2074 662 Pfam PF07670 Nucleoside recognition 517 631 4.2E-29 T 23-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 A0127_00350 9d507d13fa81abb917ca08a7960d2074 662 Pfam PF07670 Nucleoside recognition 356 450 3.0E-14 T 23-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 A0127_00350 9d507d13fa81abb917ca08a7960d2074 662 Pfam PF02421 Ferrous iron transport protein B 5 160 1.7E-64 T 23-10-2018 IPR030389 FeoB-type guanine nucleotide-binding (G) domain GO:0005525 A0127_04230 4aec72d3d4209a812957ac21450e80b9 220 Hamap MF_00350 DNA repair and recombination protein RadB [radB]. 8 217 37.82 T 23-10-2018 IPR011939 DNA repair and recombination protein RadB GO:0003684|GO:0005524|GO:0006281|GO:0006310 A0127_04230 4aec72d3d4209a812957ac21450e80b9 220 PIRSF PIRSF003336 1 220 4.7E-101 T 23-10-2018 IPR011939 DNA repair and recombination protein RadB GO:0003684|GO:0005524|GO:0006281|GO:0006310 A0127_04230 4aec72d3d4209a812957ac21450e80b9 220 SUPERFAMILY SSF52540 2 219 9.77E-40 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_04230 4aec72d3d4209a812957ac21450e80b9 220 PRINTS PR01874 DNA repair protein radA signature 11 39 5.0E-8 T 23-10-2018 A0127_04230 4aec72d3d4209a812957ac21450e80b9 220 PRINTS PR01874 DNA repair protein radA signature 190 216 5.0E-8 T 23-10-2018 A0127_04230 4aec72d3d4209a812957ac21450e80b9 220 TIGRFAM TIGR02237 recomb_radB: DNA repair and recombination protein RadB 9 217 6.2E-68 T 23-10-2018 IPR011939 DNA repair and recombination protein RadB GO:0003684|GO:0005524|GO:0006281|GO:0006310 A0127_04230 4aec72d3d4209a812957ac21450e80b9 220 Gene3D G3DSA:3.40.50.300 7 220 1.1E-62 T 23-10-2018 A0127_04230 4aec72d3d4209a812957ac21450e80b9 220 Pfam PF08423 Rad51 2 168 3.8E-29 T 23-10-2018 IPR013632 DNA recombination and repair protein Rad51-like, C-terminal Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579 A0127_02645 3637ff9926ce009bb19d6597bea85bda 319 Pfam PF03308 ArgK protein 18 281 7.8E-103 T 23-10-2018 A0127_02645 3637ff9926ce009bb19d6597bea85bda 319 TIGRFAM TIGR00750 lao: LAO/AO transport system ATPase 12 312 5.0E-130 T 23-10-2018 IPR005129 SIMIBI class G3E GTPase, ArgK/MeaB GO:0003924|GO:0005525 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 A0127_02645 3637ff9926ce009bb19d6597bea85bda 319 SMART SM00382 44 194 3.8E-5 T 23-10-2018 IPR003593 AAA+ ATPase domain A0127_02645 3637ff9926ce009bb19d6597bea85bda 319 Gene3D G3DSA:1.20.5.170 1 41 4.1E-5 T 23-10-2018 A0127_02645 3637ff9926ce009bb19d6597bea85bda 319 Gene3D G3DSA:3.40.50.300 43 252 6.4E-88 T 23-10-2018 A0127_02645 3637ff9926ce009bb19d6597bea85bda 319 SUPERFAMILY SSF52540 2 311 1.74E-80 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_07860 a21235366a9a33821144af9c8c65c3c4 444 SUPERFAMILY SSF56281 2 443 2.58E-65 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A0127_07860 a21235366a9a33821144af9c8c65c3c4 444 ProSitePatterns PS01292 Uncharacterized protein family UPF0036 signature. 382 410 - T 23-10-2018 IPR001587 Ribonuclease J, conserved site A0127_07860 a21235366a9a33821144af9c8c65c3c4 444 SMART SM00849 14 225 5.4E-23 T 23-10-2018 IPR001279 Metallo-beta-lactamase A0127_07860 a21235366a9a33821144af9c8c65c3c4 444 Hamap MF_01492 Ribonuclease J [rnj]. 1 444 49.05 T 23-10-2018 IPR030879 Ribonuclease J, archaea GO:0003723|GO:0004534|GO:0090503 A0127_07860 a21235366a9a33821144af9c8c65c3c4 444 TIGRFAM TIGR00649 MG423: beta-CASP ribonuclease, RNase J family 2 444 7.2E-157 T 23-10-2018 IPR004613 Ribonuclease J GO:0003723|GO:0046872 A0127_07860 a21235366a9a33821144af9c8c65c3c4 444 Pfam PF00753 Metallo-beta-lactamase superfamily 26 187 4.8E-13 T 23-10-2018 IPR001279 Metallo-beta-lactamase A0127_07860 a21235366a9a33821144af9c8c65c3c4 444 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 375 425 2.5E-13 T 23-10-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain A0127_07860 a21235366a9a33821144af9c8c65c3c4 444 Gene3D G3DSA:3.60.15.10 3 443 2.6E-135 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A0127_07860 a21235366a9a33821144af9c8c65c3c4 444 Gene3D G3DSA:3.40.50.10710 219 378 2.6E-135 T 23-10-2018 A0127_02575 bc3fb2de6f233a7c02bc8b4eab310d08 447 SUPERFAMILY SSF52096 7 193 1.31E-29 T 23-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A0127_02575 bc3fb2de6f233a7c02bc8b4eab310d08 447 Gene3D G3DSA:2.40.50.140 378 447 4.4E-26 T 23-10-2018 A0127_02575 bc3fb2de6f233a7c02bc8b4eab310d08 447 Pfam PF00574 Clp protease 36 191 1.7E-6 T 23-10-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA A0127_02575 bc3fb2de6f233a7c02bc8b4eab310d08 447 Pfam PF01957 NfeD-like C-terminal, partner-binding 297 442 3.5E-37 T 23-10-2018 IPR002810 NfeD-like, C-terminal domain A0127_02575 bc3fb2de6f233a7c02bc8b4eab310d08 447 SUPERFAMILY SSF141322 374 443 7.45E-19 T 23-10-2018 A0127_02575 bc3fb2de6f233a7c02bc8b4eab310d08 447 Gene3D G3DSA:3.90.226.10 22 245 2.3E-64 T 23-10-2018 A0127_07690 01f55bb2a04602d3bf8a947b8b21b31a 65 PIRSF PIRSF005653 1 65 3.4E-31 T 23-10-2018 IPR000268 DNA-directed RNA polymerase, subunit N/Rpb10 GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A0127_07690 01f55bb2a04602d3bf8a947b8b21b31a 65 ProSitePatterns PS01112 RNA polymerases N / 8 Kd subunits signature. 2 11 - T 23-10-2018 IPR020789 RNA polymerases, subunit N, zinc binding site GO:0003677|GO:0003899|GO:0006351|GO:0008270 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A0127_07690 01f55bb2a04602d3bf8a947b8b21b31a 65 ProDom PD006539 RNA POLYMERASE DNA-DIRECTED SUBUNIT TRANSFERASE NUCLEOTIDYLTRANSFERASE METAL-BINDING ZINC TRANSCRIPTION N 10 49 2.0E-16 T 23-10-2018 IPR000268 DNA-directed RNA polymerase, subunit N/Rpb10 GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A0127_07690 01f55bb2a04602d3bf8a947b8b21b31a 65 SUPERFAMILY SSF46924 1 63 1.06E-27 T 23-10-2018 IPR023580 RNA polymerase subunit RPB10 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A0127_07690 01f55bb2a04602d3bf8a947b8b21b31a 65 Gene3D G3DSA:1.10.10.60 1 65 2.2E-33 T 23-10-2018 A0127_07690 01f55bb2a04602d3bf8a947b8b21b31a 65 Pfam PF01194 RNA polymerases N / 8 kDa subunit 1 58 4.6E-30 T 23-10-2018 IPR000268 DNA-directed RNA polymerase, subunit N/Rpb10 GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A0127_07690 01f55bb2a04602d3bf8a947b8b21b31a 65 Hamap MF_00250 DNA-directed RNA polymerase subunit N [rpoN]. 1 63 23.036 T 23-10-2018 IPR000268 DNA-directed RNA polymerase, subunit N/Rpb10 GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 A0127_07040 511f87ffdd52956f813fca241c1dfa96 269 Hamap MF_00622 Exosome complex component Rrp42 [rrp42]. 1 265 45.664 T 23-10-2018 IPR020869 Exosome complex component Rrp42, archaea GO:0000178|GO:0006401 A0127_07040 511f87ffdd52956f813fca241c1dfa96 269 SUPERFAMILY SSF54211 9 212 1.37E-54 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A0127_07040 511f87ffdd52956f813fca241c1dfa96 269 Pfam PF03725 3' exoribonuclease family, domain 2 188 253 1.5E-14 T 23-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A0127_07040 511f87ffdd52956f813fca241c1dfa96 269 Pfam PF01138 3' exoribonuclease family, domain 1 30 164 3.5E-27 T 23-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A0127_07040 511f87ffdd52956f813fca241c1dfa96 269 SUPERFAMILY SSF55666 184 266 8.55E-23 T 23-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A0127_07040 511f87ffdd52956f813fca241c1dfa96 269 Gene3D G3DSA:3.30.230.70 1 268 1.2E-88 T 23-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 A0127_05985 c03a6088a91b8d2b728e515f112f2eba 1146 Gene3D G3DSA:2.60.40.10 407 497 1.8E-6 T 23-10-2018 IPR013783 Immunoglobulin-like fold A0127_05985 c03a6088a91b8d2b728e515f112f2eba 1146 SUPERFAMILY SSF50998 2 242 6.43E-16 T 23-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily A0127_05985 c03a6088a91b8d2b728e515f112f2eba 1146 Gene3D G3DSA:2.120.10.30 52 228 1.2E-10 T 23-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like A0127_05985 c03a6088a91b8d2b728e515f112f2eba 1146 SMART SM00060 388 477 61.0 T 23-10-2018 IPR003961 Fibronectin type III GO:0005515 A0127_05985 c03a6088a91b8d2b728e515f112f2eba 1146 SMART SM00060 600 659 64.0 T 23-10-2018 IPR003961 Fibronectin type III GO:0005515 A0127_05985 c03a6088a91b8d2b728e515f112f2eba 1146 SMART SM00060 837 932 7.0 T 23-10-2018 IPR003961 Fibronectin type III GO:0005515 A0127_05985 c03a6088a91b8d2b728e515f112f2eba 1146 SMART SM00060 315 385 46.0 T 23-10-2018 IPR003961 Fibronectin type III GO:0005515 A0127_05985 c03a6088a91b8d2b728e515f112f2eba 1146 SMART SM00060 952 1023 51.0 T 23-10-2018 IPR003961 Fibronectin type III GO:0005515 A0127_08355 1a9122ba49d5a2a94a60014b6d116e56 381 Pfam PF01513 ATP-NAD kinase 5 379 4.4E-46 T 23-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 A0127_08355 1a9122ba49d5a2a94a60014b6d116e56 381 PIRSF PIRSF016907 2 381 2.0E-145 T 23-10-2018 IPR011386 Putative ATP-NAD kinase A0127_08355 1a9122ba49d5a2a94a60014b6d116e56 381 Gene3D G3DSA:3.40.50.10330 110 204 1.9E-5 T 23-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 A0127_08355 1a9122ba49d5a2a94a60014b6d116e56 381 SUPERFAMILY SSF111331 91 151 1.57E-7 T 23-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily A0127_08440 5ea01e482107a05ff8c275103f4dc998 203 SUPERFAMILY SSF75689 6 38 8.11E-5 T 23-10-2018 IPR016190 Translation initiation factor IF2/IF5, zinc-binding GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 A0127_08440 5ea01e482107a05ff8c275103f4dc998 203 PIRSF PIRSF015877 1 199 4.1E-66 T 23-10-2018 IPR012041 Uncharacterised conserved protein UCP015877, zinc finger-containing A0127_02420 a878bc90e4a5f67f08de3197847100de 378 SUPERFAMILY SSF103473 11 375 4.58E-31 T 23-10-2018 IPR036259 MFS transporter superfamily A0127_02420 a878bc90e4a5f67f08de3197847100de 378 Gene3D G3DSA:1.20.1250.20 7 369 4.6E-28 T 23-10-2018 A0127_02420 a878bc90e4a5f67f08de3197847100de 378 Pfam PF07690 Major Facilitator Superfamily 17 327 8.0E-16 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A0127_10035 f661d6a8d806241be4db0cd06e5182ed 136 SMART SM00116 14 62 4.0E-10 T 23-10-2018 IPR000644 CBS domain A0127_10035 f661d6a8d806241be4db0cd06e5182ed 136 SMART SM00116 79 126 6.6E-9 T 23-10-2018 IPR000644 CBS domain A0127_10035 f661d6a8d806241be4db0cd06e5182ed 136 Pfam PF00571 CBS domain 72 124 1.3E-15 T 23-10-2018 IPR000644 CBS domain A0127_10035 f661d6a8d806241be4db0cd06e5182ed 136 Pfam PF00571 CBS domain 10 61 2.8E-11 T 23-10-2018 IPR000644 CBS domain A0127_10035 f661d6a8d806241be4db0cd06e5182ed 136 SUPERFAMILY SSF54631 9 128 1.12E-32 T 23-10-2018 A0127_10035 f661d6a8d806241be4db0cd06e5182ed 136 Gene3D G3DSA:3.10.580.10 1 136 1.2E-44 T 23-10-2018 A0127_09010 0f80883c8f4884819ffe71e4085c0a26 391 Gene3D G3DSA:3.10.580.10 1 129 9.6E-18 T 23-10-2018 A0127_09010 0f80883c8f4884819ffe71e4085c0a26 391 Pfam PF00571 CBS domain 69 122 3.5E-5 T 23-10-2018 IPR000644 CBS domain A0127_09010 0f80883c8f4884819ffe71e4085c0a26 391 Pfam PF00571 CBS domain 132 183 1.9E-16 T 23-10-2018 IPR000644 CBS domain A0127_09010 0f80883c8f4884819ffe71e4085c0a26 391 Pfam PF00571 CBS domain 211 261 1.3E-12 T 23-10-2018 IPR000644 CBS domain A0127_09010 0f80883c8f4884819ffe71e4085c0a26 391 Pfam PF00571 CBS domain 6 54 0.0035 T 23-10-2018 IPR000644 CBS domain A0127_09010 0f80883c8f4884819ffe71e4085c0a26 391 SMART SM00116 139 187 3.5E-11 T 23-10-2018 IPR000644 CBS domain A0127_09010 0f80883c8f4884819ffe71e4085c0a26 391 SMART SM00116 217 265 7.1E-9 T 23-10-2018 IPR000644 CBS domain A0127_09010 0f80883c8f4884819ffe71e4085c0a26 391 SMART SM00116 75 123 1.3 T 23-10-2018 IPR000644 CBS domain A0127_09010 0f80883c8f4884819ffe71e4085c0a26 391 SUPERFAMILY SSF54631 128 261 1.39E-34 T 23-10-2018 A0127_09010 0f80883c8f4884819ffe71e4085c0a26 391 Gene3D G3DSA:3.10.580.10 130 274 2.7E-36 T 23-10-2018 A0127_09010 0f80883c8f4884819ffe71e4085c0a26 391 SUPERFAMILY SSF54631 4 122 7.96E-18 T 23-10-2018 A0127_09010 0f80883c8f4884819ffe71e4085c0a26 391 PIRSF PIRSF036983 2 391 3.9E-145 T 23-10-2018 IPR014651 Uncharacterised conserved protein, 2xCBS, MJ1404 type A0127_06050 8a08b864ee61b98cedb72afaa7d19472 185 Gene3D G3DSA:3.40.50.300 2 183 6.1E-34 T 23-10-2018 A0127_08125 613853ca21b7c6f3ad58a69e2018cd93 236 SUPERFAMILY SSF53738 7 69 4.32E-7 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A0127_08125 613853ca21b7c6f3ad58a69e2018cd93 236 SUPERFAMILY SSF53738 127 208 1.2E-7 T 23-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A0127_08125 613853ca21b7c6f3ad58a69e2018cd93 236 Gene3D G3DSA:3.40.120.10 3 80 1.5E-6 T 23-10-2018 A0127_08125 613853ca21b7c6f3ad58a69e2018cd93 236 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 7 67 2.3E-5 T 23-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 A0127_09445 cb0d618e79e614ae8f3e16f885b6a568 127 SUPERFAMILY SSF103247 9 125 2.35E-18 T 23-10-2018 IPR035923 TT1751-like domain superfamily A0127_09445 cb0d618e79e614ae8f3e16f885b6a568 127 Pfam PF03625 Domain of unknown function DUF302 50 92 5.5E-6 T 23-10-2018 IPR005180 Domain of unknown function DUF302 A0127_09445 cb0d618e79e614ae8f3e16f885b6a568 127 Gene3D G3DSA:3.30.310.70 5 127 6.0E-15 T 23-10-2018 IPR035923 TT1751-like domain superfamily A0127_07445 4ae92ae2a839ee228d98a14e79a42461 380 SUPERFAMILY SSF56091 64 249 1.98E-37 T 23-10-2018 A0127_07445 4ae92ae2a839ee228d98a14e79a42461 380 Pfam PF09414 RNA ligase 86 240 9.5E-18 T 23-10-2018 IPR021122 RNA ligase domain, REL/Rln2 A0127_07445 4ae92ae2a839ee228d98a14e79a42461 380 Gene3D G3DSA:3.30.1490.70 70 241 8.7E-70 T 23-10-2018 A0127_07445 4ae92ae2a839ee228d98a14e79a42461 380 PRINTS PR01048 Hypothetical protein Y414 family signature 164 185 4.7E-52 T 23-10-2018 IPR001072 RNA ligase, Pab1020 family A0127_07445 4ae92ae2a839ee228d98a14e79a42461 380 PRINTS PR01048 Hypothetical protein Y414 family signature 355 375 4.7E-52 T 23-10-2018 IPR001072 RNA ligase, Pab1020 family A0127_07445 4ae92ae2a839ee228d98a14e79a42461 380 PRINTS PR01048 Hypothetical protein Y414 family signature 87 100 4.7E-52 T 23-10-2018 IPR001072 RNA ligase, Pab1020 family A0127_07445 4ae92ae2a839ee228d98a14e79a42461 380 PRINTS PR01048 Hypothetical protein Y414 family signature 291 305 4.7E-52 T 23-10-2018 IPR001072 RNA ligase, Pab1020 family A0127_07445 4ae92ae2a839ee228d98a14e79a42461 380 PRINTS PR01048 Hypothetical protein Y414 family signature 42 56 4.7E-52 T 23-10-2018 IPR001072 RNA ligase, Pab1020 family A0127_07445 4ae92ae2a839ee228d98a14e79a42461 380 PRINTS PR01048 Hypothetical protein Y414 family signature 138 153 4.7E-52 T 23-10-2018 IPR001072 RNA ligase, Pab1020 family A0127_07445 4ae92ae2a839ee228d98a14e79a42461 380 PRINTS PR01048 Hypothetical protein Y414 family signature 260 278 4.7E-52 T 23-10-2018 IPR001072 RNA ligase, Pab1020 family A0127_07445 4ae92ae2a839ee228d98a14e79a42461 380 PRINTS PR01048 Hypothetical protein Y414 family signature 108 123 4.7E-52 T 23-10-2018 IPR001072 RNA ligase, Pab1020 family A0127_07445 4ae92ae2a839ee228d98a14e79a42461 380 PRINTS PR01048 Hypothetical protein Y414 family signature 219 232 4.7E-52 T 23-10-2018 IPR001072 RNA ligase, Pab1020 family A0127_07445 4ae92ae2a839ee228d98a14e79a42461 380 PRINTS PR01048 Hypothetical protein Y414 family signature 64 82 4.7E-52 T 23-10-2018 IPR001072 RNA ligase, Pab1020 family A0127_07445 4ae92ae2a839ee228d98a14e79a42461 380 Gene3D G3DSA:3.30.470.30 96 197 8.7E-70 T 23-10-2018 A0127_07445 4ae92ae2a839ee228d98a14e79a42461 380 Gene3D G3DSA:3.30.70.3350 244 374 4.4E-37 T 23-10-2018 A0127_07445 4ae92ae2a839ee228d98a14e79a42461 380 TIGRFAM TIGR01209 TIGR01209: RNA ligase, Pab1020 family 11 380 4.1E-143 T 23-10-2018 IPR001072 RNA ligase, Pab1020 family A0127_07445 4ae92ae2a839ee228d98a14e79a42461 380 Gene3D G3DSA:3.30.70.3360 314 362 4.4E-37 T 23-10-2018 A0127_07445 4ae92ae2a839ee228d98a14e79a42461 380 Gene3D G3DSA:2.20.25.320 7 67 2.7E-21 T 23-10-2018 A0127_05020 3bc6f537f77f89b64cdc094649da6b68 394 SUPERFAMILY SSF52518 5 251 9.42E-70 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold A0127_05020 3bc6f537f77f89b64cdc094649da6b68 394 Gene3D G3DSA:3.40.50.970 3 252 4.6E-104 T 23-10-2018 A0127_05020 3bc6f537f77f89b64cdc094649da6b68 394 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 16 239 1.1E-80 T 23-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 A0127_05020 3bc6f537f77f89b64cdc094649da6b68 394 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 262 364 7.3E-29 T 23-10-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II A0127_05020 3bc6f537f77f89b64cdc094649da6b68 394 SUPERFAMILY SSF52922 254 368 2.75E-32 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A0127_05020 3bc6f537f77f89b64cdc094649da6b68 394 Gene3D G3DSA:3.40.50.920 253 391 1.4E-39 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A0127_00535 c7168ed751ce1e5992b245cf91d02d33 408 ProSitePatterns PS00066 Hydroxymethylglutaryl-coenzyme A reductases signature 1. 187 201 - T 23-10-2018 IPR023076 Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A0127_00535 c7168ed751ce1e5992b245cf91d02d33 408 TIGRFAM TIGR00533 HMG_CoA_R_NADP: hydroxymethylglutaryl-CoA reductase (NADPH) 2 408 1.8E-166 T 23-10-2018 IPR004554 Hydroxymethylglutaryl-CoA reductase, eukaryotic/archaeal type GO:0004420|GO:0008299|GO:0016021|GO:0050661|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A0127_00535 c7168ed751ce1e5992b245cf91d02d33 408 Gene3D G3DSA:3.30.70.420 129 244 5.2E-132 T 23-10-2018 IPR009023 Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain superfamily GO:0050662 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A0127_00535 c7168ed751ce1e5992b245cf91d02d33 408 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 276 302 2.1E-58 T 23-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A0127_00535 c7168ed751ce1e5992b245cf91d02d33 408 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 64 85 2.1E-58 T 23-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A0127_00535 c7168ed751ce1e5992b245cf91d02d33 408 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 95 115 2.1E-58 T 23-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A0127_00535 c7168ed751ce1e5992b245cf91d02d33 408 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 328 349 2.1E-58 T 23-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A0127_00535 c7168ed751ce1e5992b245cf91d02d33 408 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 185 203 2.1E-58 T 23-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A0127_00535 c7168ed751ce1e5992b245cf91d02d33 408 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 225 250 2.1E-58 T 23-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A0127_00535 c7168ed751ce1e5992b245cf91d02d33 408 Gene3D G3DSA:3.90.770.10 75 395 5.2E-132 T 23-10-2018 IPR023074 Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic domain superfamily GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A0127_00535 c7168ed751ce1e5992b245cf91d02d33 408 ProSitePatterns PS00318 Hydroxymethylglutaryl-coenzyme A reductases signature 2. 340 347 - T 23-10-2018 IPR023076 Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A0127_00535 c7168ed751ce1e5992b245cf91d02d33 408 SUPERFAMILY SSF55035 129 244 1.05E-39 T 23-10-2018 IPR009023 Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain superfamily GO:0050662 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A0127_00535 c7168ed751ce1e5992b245cf91d02d33 408 Gene3D G3DSA:1.10.3270.10 1 74 2.3E-7 T 23-10-2018 IPR023282 Hydroxymethylglutaryl-CoA reductase, N-terminal GO:0004420 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A0127_00535 c7168ed751ce1e5992b245cf91d02d33 408 Pfam PF00368 Hydroxymethylglutaryl-coenzyme A reductase 32 408 9.7E-140 T 23-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A0127_00535 c7168ed751ce1e5992b245cf91d02d33 408 SUPERFAMILY SSF56542 4 398 2.75E-93 T 23-10-2018 IPR009029 Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding domain superfamily GO:0015936|GO:0016616|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 A0127_09030 82c5c05ec4a7ce4ec2d33cb368c9df3c 279 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A0127_09030 82c5c05ec4a7ce4ec2d33cb368c9df3c 279 SUPERFAMILY SSF52540 3 238 7.55E-58 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_09030 82c5c05ec4a7ce4ec2d33cb368c9df3c 279 Gene3D G3DSA:3.40.50.300 2 258 9.0E-71 T 23-10-2018 A0127_09030 82c5c05ec4a7ce4ec2d33cb368c9df3c 279 Pfam PF00005 ABC transporter 21 178 4.8E-24 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A0127_09030 82c5c05ec4a7ce4ec2d33cb368c9df3c 279 SMART SM00382 30 226 3.8E-14 T 23-10-2018 IPR003593 AAA+ ATPase domain A0127_05780 77918c60fb7d9f6b19357af1a95e8eda 180 Gene3D G3DSA:3.40.220.10 1 180 1.4E-54 T 23-10-2018 A0127_05780 77918c60fb7d9f6b19357af1a95e8eda 180 SMART SM00506 3 146 3.7E-51 T 23-10-2018 IPR002589 Macro domain A0127_05780 77918c60fb7d9f6b19357af1a95e8eda 180 Pfam PF01661 Macro domain 20 145 6.7E-34 T 23-10-2018 IPR002589 Macro domain A0127_05780 77918c60fb7d9f6b19357af1a95e8eda 180 SUPERFAMILY SSF52949 4 177 1.31E-49 T 23-10-2018 A0127_09430 b1d465c015995b3beb84652b39642004 375 TIGRFAM TIGR00075 hypD: hydrogenase expression/formation protein HypD 5 372 8.3E-136 T 23-10-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 A0127_09430 b1d465c015995b3beb84652b39642004 375 Gene3D G3DSA:3.40.50.11740 66 307 8.5E-112 T 23-10-2018 A0127_09430 b1d465c015995b3beb84652b39642004 375 Pfam PF01924 Hydrogenase formation hypA family 16 372 2.1E-135 T 23-10-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 A0127_09430 b1d465c015995b3beb84652b39642004 375 Gene3D G3DSA:3.40.50.11750 20 267 8.5E-112 T 23-10-2018 A0127_09430 b1d465c015995b3beb84652b39642004 375 Gene3D G3DSA:1.10.10.2140 323 375 6.8E-26 T 23-10-2018 A0127_09430 b1d465c015995b3beb84652b39642004 375 PIRSF PIRSF005622 5 375 1.5E-145 T 23-10-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 A0127_01570 898323b216b4f646a428027dcbd5c28f 259 Gene3D G3DSA:3.40.50.720 2 258 7.2E-48 T 23-10-2018 A0127_01570 898323b216b4f646a428027dcbd5c28f 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 1.1E-17 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A0127_01570 898323b216b4f646a428027dcbd5c28f 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 1.1E-17 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A0127_01570 898323b216b4f646a428027dcbd5c28f 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 189 1.1E-17 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A0127_01570 898323b216b4f646a428027dcbd5c28f 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 217 237 1.1E-17 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A0127_01570 898323b216b4f646a428027dcbd5c28f 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 2 19 1.1E-17 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A0127_01570 898323b216b4f646a428027dcbd5c28f 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 75 86 1.1E-17 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A0127_01570 898323b216b4f646a428027dcbd5c28f 259 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 10 253 1.5E-32 T 23-10-2018 A0127_01570 898323b216b4f646a428027dcbd5c28f 259 SUPERFAMILY SSF51735 2 254 5.79E-51 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A0127_03585 ebeb506ce90e561a734ead63ce2cb929 532 Pfam PF01841 Transglutaminase-like superfamily 294 388 2.4E-6 T 23-10-2018 IPR002931 Transglutaminase-like A0127_03585 ebeb506ce90e561a734ead63ce2cb929 532 Gene3D G3DSA:3.10.620.30 262 405 7.4E-7 T 23-10-2018 A0127_03585 ebeb506ce90e561a734ead63ce2cb929 532 SUPERFAMILY SSF54001 266 443 4.35E-10 T 23-10-2018 IPR038765 Papain-like cysteine peptidase superfamily A0127_03585 ebeb506ce90e561a734ead63ce2cb929 532 SMART SM00460 333 391 0.0055 T 23-10-2018 IPR002931 Transglutaminase-like A0127_04570 ca2a3e55bc73b66448adf17d952ee69b 204 Gene3D G3DSA:3.90.1720.10 44 202 3.3E-16 T 23-10-2018 A0127_04570 ca2a3e55bc73b66448adf17d952ee69b 204 SUPERFAMILY SSF54001 43 200 5.56E-28 T 23-10-2018 IPR038765 Papain-like cysteine peptidase superfamily A0127_04570 ca2a3e55bc73b66448adf17d952ee69b 204 Pfam PF05708 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family 44 200 1.2E-39 T 23-10-2018 IPR024453 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family A0127_03355 fa2578ce0d37d350003c12d5c0dd8b4d 202 SUPERFAMILY SSF53323 4 199 2.48E-44 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 A0127_03355 fa2578ce0d37d350003c12d5c0dd8b4d 202 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 12 193 3.8E-38 T 23-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 A0127_03355 fa2578ce0d37d350003c12d5c0dd8b4d 202 Gene3D G3DSA:3.40.920.10 1 201 2.9E-50 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 A0127_03355 fa2578ce0d37d350003c12d5c0dd8b4d 202 TIGRFAM TIGR03334 IOR_beta: indolepyruvate ferredoxin oxidoreductase, beta subunit 4 194 1.9E-96 T 23-10-2018 IPR017719 Indolepyruvate ferredoxin oxidoreductase, beta subunit GO:0043805|GO:0055114 A0127_02505 d3e44b403de39e82b4c6ed62c1a266b0 142 Gene3D G3DSA:3.55.10.10 1 142 6.4E-52 T 23-10-2018 IPR036820 Archease domain superfamily Reactome: R-HSA-6784531 A0127_02505 d3e44b403de39e82b4c6ed62c1a266b0 142 Pfam PF01951 Archease protein family (MTH1598/TM1083) 4 141 1.4E-46 T 23-10-2018 IPR023572 Archease domain Reactome: R-HSA-6784531 A0127_02505 d3e44b403de39e82b4c6ed62c1a266b0 142 SUPERFAMILY SSF69819 2 142 5.36E-48 T 23-10-2018 IPR036820 Archease domain superfamily Reactome: R-HSA-6784531 A0127_02505 d3e44b403de39e82b4c6ed62c1a266b0 142 Hamap MF_01222 Protein archease. 2 142 41.525 T 23-10-2018 IPR022952 Archease, archaea A0127_02505 d3e44b403de39e82b4c6ed62c1a266b0 142 ProDom PD012969 UPF0211 RIKEN CDNA ENRICHED MALE FULL-LENGTH LIBRARY ZBTB8OS ADULT C43H8.1 8 142 5.0E-46 T 23-10-2018 IPR023572 Archease domain Reactome: R-HSA-6784531 A0127_09915 8fcb23271498010b87a2444c2e1cd942 183 Gene3D G3DSA:1.20.1260.10 4 160 5.8E-63 T 23-10-2018 IPR012347 Ferritin-like A0127_09915 8fcb23271498010b87a2444c2e1cd942 183 Pfam PF00210 Ferritin-like domain 21 159 9.8E-21 T 23-10-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 A0127_09915 8fcb23271498010b87a2444c2e1cd942 183 SUPERFAMILY SSF47240 3 158 8.92E-30 T 23-10-2018 IPR009078 Ferritin-like superfamily A0127_09915 8fcb23271498010b87a2444c2e1cd942 183 PIRSF PIRSF018063 1 168 4.9E-67 T 23-10-2018 IPR014490 DNA-binding protein from starved cells-like A0127_01140 a0028ba759c4dde5112672d4969cf4bd 269 Pfam PF01889 Membrane protein of unknown function DUF63 3 268 2.5E-89 T 23-10-2018 IPR002749 Protein of unknown function DUF63 A0127_02250 0873cdad9348d7dd5235a44fccdabfd2 219 SUPERFAMILY SSF56104 2 214 1.01E-50 T 23-10-2018 A0127_02250 0873cdad9348d7dd5235a44fccdabfd2 219 ProSitePatterns PS01058 SAICAR synthetase signature 2. 175 183 - T 23-10-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A0127_02250 0873cdad9348d7dd5235a44fccdabfd2 219 Pfam PF01259 SAICAR synthetase 4 206 6.7E-34 T 23-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A0127_02250 0873cdad9348d7dd5235a44fccdabfd2 219 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 1 219 19.341 T 23-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A0127_02250 0873cdad9348d7dd5235a44fccdabfd2 219 Gene3D G3DSA:3.30.470.20 87 207 4.3E-59 T 23-10-2018 A0127_02250 0873cdad9348d7dd5235a44fccdabfd2 219 Gene3D G3DSA:3.30.200.20 4 86 4.3E-59 T 23-10-2018 A0127_04830 4f1259a9e7b72506843c4c6bf3f0ad5b 559 Gene3D G3DSA:1.10.3260.10 1 220 7.7E-87 T 23-10-2018 IPR036599 DNA ligase, ATP-dependent, N-terminal domain superfamily GO:0003677|GO:0003910|GO:0006281|GO:0006310 A0127_04830 4f1259a9e7b72506843c4c6bf3f0ad5b 559 Hamap MF_00407 DNA ligase [lig]. 1 550 34.398 T 23-10-2018 IPR022865 DNA ligase, ATP-dependent, bacterial/archaeal GO:0003910 A0127_04830 4f1259a9e7b72506843c4c6bf3f0ad5b 559 Gene3D G3DSA:2.40.50.140 423 559 3.6E-53 T 23-10-2018 A0127_04830 4f1259a9e7b72506843c4c6bf3f0ad5b 559 Pfam PF04675 DNA ligase N terminus 3 176 6.3E-40 T 23-10-2018 IPR012308 DNA ligase, ATP-dependent, N-terminal GO:0003677|GO:0003910|GO:0006281|GO:0006310 A0127_04830 4f1259a9e7b72506843c4c6bf3f0ad5b 559 Gene3D G3DSA:3.30.470.30 221 422 2.2E-73 T 23-10-2018 A0127_04830 4f1259a9e7b72506843c4c6bf3f0ad5b 559 SUPERFAMILY SSF56091 219 422 1.75E-53 T 23-10-2018 A0127_04830 4f1259a9e7b72506843c4c6bf3f0ad5b 559 Pfam PF01068 ATP dependent DNA ligase domain 224 422 4.4E-64 T 23-10-2018 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 A0127_04830 4f1259a9e7b72506843c4c6bf3f0ad5b 559 SUPERFAMILY SSF50249 426 552 4.97E-41 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A0127_04830 4f1259a9e7b72506843c4c6bf3f0ad5b 559 Pfam PF04679 ATP dependent DNA ligase C terminal region 443 534 1.8E-21 T 23-10-2018 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 A0127_04830 4f1259a9e7b72506843c4c6bf3f0ad5b 559 ProSitePatterns PS00697 ATP-dependent DNA ligase AMP-binding site. 247 255 - T 23-10-2018 IPR016059 DNA ligase, ATP-dependent, conserved site GO:0003909|GO:0051103 A0127_04830 4f1259a9e7b72506843c4c6bf3f0ad5b 559 ProSitePatterns PS00333 ATP-dependent DNA ligase signature 2. 398 422 - T 23-10-2018 IPR016059 DNA ligase, ATP-dependent, conserved site GO:0003909|GO:0051103 A0127_04830 4f1259a9e7b72506843c4c6bf3f0ad5b 559 SUPERFAMILY SSF117018 2 241 1.31E-71 T 23-10-2018 IPR036599 DNA ligase, ATP-dependent, N-terminal domain superfamily GO:0003677|GO:0003910|GO:0006281|GO:0006310 A0127_04830 4f1259a9e7b72506843c4c6bf3f0ad5b 559 TIGRFAM TIGR00574 dnl1: DNA ligase I, ATP-dependent (dnl1) 57 550 3.4E-167 T 23-10-2018 IPR000977 DNA ligase, ATP-dependent GO:0003910|GO:0005524|GO:0006281|GO:0006310|GO:0071897 A0127_09000 cea5606c1cdc568bee851f3baf0aae7e 419 SUPERFAMILY SSF51161 243 409 1.71E-39 T 23-10-2018 IPR011004 Trimeric LpxA-like superfamily A0127_09000 cea5606c1cdc568bee851f3baf0aae7e 419 Gene3D G3DSA:3.90.550.10 1 224 2.7E-54 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A0127_09000 cea5606c1cdc568bee851f3baf0aae7e 419 Gene3D G3DSA:2.160.10.10 225 410 3.6E-60 T 23-10-2018 A0127_09000 cea5606c1cdc568bee851f3baf0aae7e 419 SUPERFAMILY SSF53448 1 312 5.63E-72 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A0127_09000 cea5606c1cdc568bee851f3baf0aae7e 419 TIGRFAM TIGR03992 Arch_glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 1 398 3.2E-155 T 23-10-2018 IPR023915 UDP-GlcNAc diphosphorylase/GlcNAc-1-P N-acetyltransferase, GlmU, archaeal-type GO:0003977|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|MetaCyc: PWY-5514 A0127_09000 cea5606c1cdc568bee851f3baf0aae7e 419 Pfam PF00483 Nucleotidyl transferase 2 232 1.0E-39 T 23-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 A0127_09000 cea5606c1cdc568bee851f3baf0aae7e 419 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 254 287 3.7E-9 T 23-10-2018 IPR001451 Hexapeptide repeat A0127_09000 cea5606c1cdc568bee851f3baf0aae7e 419 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 365 399 1.2E-5 T 23-10-2018 IPR001451 Hexapeptide repeat A0127_07295 e25d706f4b8c8cbd1832cc1e23dfeb17 592 Pfam PF00583 Acetyltransferase (GNAT) family 460 562 3.0E-8 T 23-10-2018 IPR000182 GNAT domain A0127_07295 e25d706f4b8c8cbd1832cc1e23dfeb17 592 Pfam PF16199 Radical_SAM C-terminal domain 336 415 1.4E-26 T 23-10-2018 IPR032432 Radical SAM, C-terminal extension Reactome: R-HSA-3214847 A0127_07295 e25d706f4b8c8cbd1832cc1e23dfeb17 592 PIRSF PIRSF005669 1 574 2.5E-249 T 23-10-2018 IPR034687 Elongator complex protein 3-like Reactome: R-HSA-3214847 A0127_07295 e25d706f4b8c8cbd1832cc1e23dfeb17 592 SMART SM00729 80 375 1.6E-48 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A0127_07295 e25d706f4b8c8cbd1832cc1e23dfeb17 592 SUPERFAMILY SSF55729 449 569 3.17E-10 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase A0127_07295 e25d706f4b8c8cbd1832cc1e23dfeb17 592 Gene3D G3DSA:3.80.30.20 233 383 2.1E-13 T 23-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe A0127_07295 e25d706f4b8c8cbd1832cc1e23dfeb17 592 SUPERFAMILY SSF102114 85 382 3.92E-35 T 23-10-2018 A0127_07295 e25d706f4b8c8cbd1832cc1e23dfeb17 592 Pfam PF04055 Radical SAM superfamily 87 320 9.4E-33 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A0127_07295 e25d706f4b8c8cbd1832cc1e23dfeb17 592 TIGRFAM TIGR01211 ELP3: radical SAM enzyme/protein acetyltransferase, ELP3 family 14 573 6.6E-264 T 23-10-2018 IPR034687 Elongator complex protein 3-like Reactome: R-HSA-3214847 A0127_07295 e25d706f4b8c8cbd1832cc1e23dfeb17 592 Gene3D G3DSA:3.40.630.30 423 573 1.2E-8 T 23-10-2018 A0127_07440 03b858d22c3ccfdf2f51d01d2038d756 182 Gene3D G3DSA:3.90.1170.10 1 181 1.9E-64 T 23-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 A0127_07440 03b858d22c3ccfdf2f51d01d2038d756 182 SUPERFAMILY SSF54686 4 168 8.63E-57 T 23-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 A0127_07440 03b858d22c3ccfdf2f51d01d2038d756 182 Hamap MF_00448 50S ribosomal protein L10e [rpl10e]. 1 174 36.805 T 23-10-2018 IPR022981 Ribosomal protein L10e, archaea A0127_07440 03b858d22c3ccfdf2f51d01d2038d756 182 Pfam PF00252 Ribosomal protein L16p/L10e 14 159 1.1E-32 T 23-10-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 A0127_07440 03b858d22c3ccfdf2f51d01d2038d756 182 ProSitePatterns PS01257 Ribosomal protein L10e signature. 105 126 - T 23-10-2018 IPR018255 Ribosomal protein L10e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_07440 03b858d22c3ccfdf2f51d01d2038d756 182 PIRSF PIRSF005590 1 180 2.6E-69 T 23-10-2018 IPR001197 Ribosomal protein L10e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_04400 04b655e44cd23e490b25b9e88f7db854 138 SUPERFAMILY SSF103481 40 137 1.05E-12 T 23-10-2018 A0127_04400 04b655e44cd23e490b25b9e88f7db854 138 Pfam PF00892 EamA-like transporter family 4 137 3.9E-23 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A0127_04475 05a0da6ce711453174d7183c11e63fa8 372 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 94 132 - T 23-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 A0127_04475 05a0da6ce711453174d7183c11e63fa8 372 Gene3D G3DSA:3.30.70.360 168 279 1.5E-76 T 23-10-2018 A0127_04475 05a0da6ce711453174d7183c11e63fa8 372 SUPERFAMILY SSF53187 4 369 1.0E-54 T 23-10-2018 A0127_04475 05a0da6ce711453174d7183c11e63fa8 372 SUPERFAMILY SSF55031 167 275 2.39E-13 T 23-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain A0127_04475 05a0da6ce711453174d7183c11e63fa8 372 Pfam PF01546 Peptidase family M20/M25/M40 62 366 3.8E-31 T 23-10-2018 IPR002933 Peptidase M20 GO:0016787 A0127_04475 05a0da6ce711453174d7183c11e63fa8 372 Pfam PF07687 Peptidase dimerisation domain 165 266 3.3E-9 T 23-10-2018 IPR011650 Peptidase M20, dimerisation domain A0127_04475 05a0da6ce711453174d7183c11e63fa8 372 Gene3D G3DSA:3.40.630.10 6 357 1.5E-76 T 23-10-2018 A0127_08710 03e0f8a354d54b80090bef6831f8c10e 186 Gene3D G3DSA:1.25.10.10 15 163 1.1E-8 T 23-10-2018 IPR011989 Armadillo-like helical A0127_08710 03e0f8a354d54b80090bef6831f8c10e 186 SUPERFAMILY SSF48371 30 148 3.4E-13 T 23-10-2018 IPR016024 Armadillo-type fold A0127_03095 5e4c9652c6eebebe747474b7be87d6d4 134 SUPERFAMILY SSF50249 8 116 2.06E-32 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A0127_03095 5e4c9652c6eebebe747474b7be87d6d4 134 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 50 112 2.0E-21 T 23-10-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal A0127_03095 5e4c9652c6eebebe747474b7be87d6d4 134 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 17 47 6.5E-10 T 23-10-2018 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal A0127_03990 d34329da3627fb3763ec801fef81a669 172 PIRSF PIRSF005067 1 172 6.1E-43 T 23-10-2018 IPR016437 MCT-1/Tma20 A0127_03990 d34329da3627fb3763ec801fef81a669 172 Gene3D G3DSA:2.30.130.10 79 171 1.9E-35 T 23-10-2018 IPR036974 PUA domain superfamily GO:0003723 A0127_03990 d34329da3627fb3763ec801fef81a669 172 Gene3D G3DSA:3.10.450.120 1 78 1.9E-36 T 23-10-2018 A0127_03990 d34329da3627fb3763ec801fef81a669 172 TIGRFAM TIGR03684 arCOG00985: arCOG04150 universal archaeal PUA-domain protein 6 168 2.4E-59 T 23-10-2018 IPR022430 Conserved hypothetical protein CHP03684 A0127_03990 d34329da3627fb3763ec801fef81a669 172 SUPERFAMILY SSF88697 88 169 1.27E-23 T 23-10-2018 IPR015947 PUA-like superfamily A0127_03990 d34329da3627fb3763ec801fef81a669 172 TIGRFAM TIGR00451 unchar_dom_2: uncharacterized domain 2 53 164 8.6E-31 T 23-10-2018 IPR004521 Uncharacterised domain CHP00451 GO:0003723 A0127_03990 d34329da3627fb3763ec801fef81a669 172 SMART SM00359 88 163 1.1E-22 T 23-10-2018 IPR002478 PUA domain GO:0003723 A0127_03990 d34329da3627fb3763ec801fef81a669 172 Pfam PF09183 Domain of unknown function (DUF1947) 6 75 7.6E-7 T 23-10-2018 IPR015266 Domain of unknown function DUF1947 A0127_03990 d34329da3627fb3763ec801fef81a669 172 Pfam PF01472 PUA domain 89 161 1.3E-23 T 23-10-2018 IPR002478 PUA domain GO:0003723 A0127_01785 fa8b736cdbac5380e88e6449041d670a 185 Pfam PF02441 Flavoprotein 1 156 5.7E-29 T 23-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 A0127_01785 fa8b736cdbac5380e88e6449041d670a 185 TIGRFAM TIGR00421 ubiX_pad: polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylases 2 175 6.8E-73 T 23-10-2018 IPR004507 Flavin prenyltransferase UbiX-like A0127_01785 fa8b736cdbac5380e88e6449041d670a 185 Hamap MF_01984 Flavin prenyltransferase UbiX [ubiX]. 1 177 38.175 T 23-10-2018 IPR004507 Flavin prenyltransferase UbiX-like A0127_01785 fa8b736cdbac5380e88e6449041d670a 185 Gene3D G3DSA:3.40.50.1950 1 182 4.9E-76 T 23-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 A0127_01785 fa8b736cdbac5380e88e6449041d670a 185 SUPERFAMILY SSF52507 1 176 1.96E-60 T 23-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 A0127_05870 e986f3cbc59cde155fad23ab9d09566a 384 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 81 90 - T 23-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A0127_05870 e986f3cbc59cde155fad23ab9d09566a 384 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 73 380 5.1E-106 T 23-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 A0127_05870 e986f3cbc59cde155fad23ab9d09566a 384 SUPERFAMILY SSF52374 4 368 1.45E-92 T 23-10-2018 A0127_05870 e986f3cbc59cde155fad23ab9d09566a 384 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 208 229 2.1E-20 T 23-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 A0127_05870 e986f3cbc59cde155fad23ab9d09566a 384 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 85 101 2.1E-20 T 23-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 A0127_05870 e986f3cbc59cde155fad23ab9d09566a 384 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 252 262 2.1E-20 T 23-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 A0127_05870 e986f3cbc59cde155fad23ab9d09566a 384 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 138 157 2.1E-20 T 23-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 A0127_05870 e986f3cbc59cde155fad23ab9d09566a 384 Pfam PF00579 tRNA synthetases class I (W and Y) 73 347 1.7E-27 T 23-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 A0127_05870 e986f3cbc59cde155fad23ab9d09566a 384 Gene3D G3DSA:3.40.50.620 1 255 4.0E-104 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A0127_05870 e986f3cbc59cde155fad23ab9d09566a 384 Gene3D G3DSA:1.10.240.10 256 383 1.0E-43 T 23-10-2018 A0127_05870 e986f3cbc59cde155fad23ab9d09566a 384 Hamap MF_00140_A Tryptophan--tRNA ligase [trpS]. 5 366 46.188 T 23-10-2018 IPR020653 Tryptophan-tRNA ligase, archaea GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 A0127_03835 387b507fa24149c01a0871df2de00c03 215 Gene3D G3DSA:3.30.2010.10 106 199 1.7E-20 T 23-10-2018 A0127_03835 387b507fa24149c01a0871df2de00c03 215 Pfam PF01863 Protein of unknown function DUF45 11 197 7.0E-50 T 23-10-2018 IPR002725 Protein of unknown function DUF45 A0127_03940 e50a5aebd3fb8e0289e4300c0a147fbb 303 Pfam PF08271 TFIIB zinc-binding 6 47 1.7E-19 T 23-10-2018 IPR013137 Zinc finger, TFIIB-type A0127_03940 e50a5aebd3fb8e0289e4300c0a147fbb 303 PRINTS PR00685 Transcription initiation factor IIB signature 281 295 1.6E-58 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 A0127_03940 e50a5aebd3fb8e0289e4300c0a147fbb 303 PRINTS PR00685 Transcription initiation factor IIB signature 162 181 1.6E-58 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 A0127_03940 e50a5aebd3fb8e0289e4300c0a147fbb 303 PRINTS PR00685 Transcription initiation factor IIB signature 249 265 1.6E-58 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 A0127_03940 e50a5aebd3fb8e0289e4300c0a147fbb 303 PRINTS PR00685 Transcription initiation factor IIB signature 19 39 1.6E-58 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 A0127_03940 e50a5aebd3fb8e0289e4300c0a147fbb 303 PRINTS PR00685 Transcription initiation factor IIB signature 41 54 1.6E-58 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 A0127_03940 e50a5aebd3fb8e0289e4300c0a147fbb 303 PRINTS PR00685 Transcription initiation factor IIB signature 54 75 1.6E-58 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 A0127_03940 e50a5aebd3fb8e0289e4300c0a147fbb 303 PRINTS PR00685 Transcription initiation factor IIB signature 215 233 1.6E-58 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 A0127_03940 e50a5aebd3fb8e0289e4300c0a147fbb 303 PRINTS PR00685 Transcription initiation factor IIB signature 188 203 1.6E-58 T 23-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 A0127_03940 e50a5aebd3fb8e0289e4300c0a147fbb 303 ProSitePatterns PS00782 Transcription factor TFIIB repeat signature. 154 169 - T 23-10-2018 IPR023486 Transcription factor TFIIB, conserved site Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-674695|Reactome: R-HSA-6807505|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-76042 A0127_03940 e50a5aebd3fb8e0289e4300c0a147fbb 303 SMART SM00385 214 295 8.1E-11 T 23-10-2018 IPR013763 Cyclin-like A0127_03940 e50a5aebd3fb8e0289e4300c0a147fbb 303 SMART SM00385 120 201 2.4E-13 T 23-10-2018 IPR013763 Cyclin-like A0127_03940 e50a5aebd3fb8e0289e4300c0a147fbb 303 Gene3D G3DSA:1.10.472.10 211 303 2.8E-26 T 23-10-2018 A0127_03940 e50a5aebd3fb8e0289e4300c0a147fbb 303 Gene3D G3DSA:1.10.472.170 6 202 2.0E-66 T 23-10-2018 A0127_03940 e50a5aebd3fb8e0289e4300c0a147fbb 303 Pfam PF00382 Transcription factor TFIIB repeat 123 192 4.1E-19 T 23-10-2018 IPR013150 Transcription factor TFIIB, cyclin-like domain GO:0017025 A0127_03940 e50a5aebd3fb8e0289e4300c0a147fbb 303 Pfam PF00382 Transcription factor TFIIB repeat 216 286 8.7E-19 T 23-10-2018 IPR013150 Transcription factor TFIIB, cyclin-like domain GO:0017025 A0127_03940 e50a5aebd3fb8e0289e4300c0a147fbb 303 SUPERFAMILY SSF47954 211 302 1.22E-28 T 23-10-2018 IPR036915 Cyclin-like superfamily A0127_03940 e50a5aebd3fb8e0289e4300c0a147fbb 303 SUPERFAMILY SSF57783 4 50 1.19E-17 T 23-10-2018 A0127_03940 e50a5aebd3fb8e0289e4300c0a147fbb 303 ProSitePatterns PS00782 Transcription factor TFIIB repeat signature. 248 263 - T 23-10-2018 IPR023486 Transcription factor TFIIB, conserved site Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-674695|Reactome: R-HSA-6807505|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-76042 A0127_03940 e50a5aebd3fb8e0289e4300c0a147fbb 303 Hamap MF_00383 Transcription initiation factor IIB [tfb]. 1 301 46.657 T 23-10-2018 IPR023484 Transcription initiation factor TFIIB, archaea A0127_03940 e50a5aebd3fb8e0289e4300c0a147fbb 303 SUPERFAMILY SSF47954 114 207 3.69E-26 T 23-10-2018 IPR036915 Cyclin-like superfamily A0127_08450 1dee7694254bfddd6a06be1172d51b1e 317 SUPERFAMILY SSF117892 53 186 7.32E-47 T 23-10-2018 IPR036013 Band 7/SPFH domain superfamily A0127_08450 1dee7694254bfddd6a06be1172d51b1e 317 PRINTS PR00721 Stomatin signature 174 195 3.7E-35 T 23-10-2018 IPR001972 Stomatin family GO:0016020 A0127_08450 1dee7694254bfddd6a06be1172d51b1e 317 PRINTS PR00721 Stomatin signature 131 154 3.7E-35 T 23-10-2018 IPR001972 Stomatin family GO:0016020 A0127_08450 1dee7694254bfddd6a06be1172d51b1e 317 PRINTS PR00721 Stomatin signature 111 128 3.7E-35 T 23-10-2018 IPR001972 Stomatin family GO:0016020 A0127_08450 1dee7694254bfddd6a06be1172d51b1e 317 PRINTS PR00721 Stomatin signature 76 97 3.7E-35 T 23-10-2018 IPR001972 Stomatin family GO:0016020 A0127_08450 1dee7694254bfddd6a06be1172d51b1e 317 PRINTS PR00721 Stomatin signature 29 51 3.7E-35 T 23-10-2018 IPR001972 Stomatin family GO:0016020 A0127_08450 1dee7694254bfddd6a06be1172d51b1e 317 PRINTS PR00721 Stomatin signature 155 173 3.7E-35 T 23-10-2018 IPR001972 Stomatin family GO:0016020 A0127_08450 1dee7694254bfddd6a06be1172d51b1e 317 Pfam PF01145 SPFH domain / Band 7 family 26 195 4.3E-42 T 23-10-2018 IPR001107 Band 7 domain A0127_08450 1dee7694254bfddd6a06be1172d51b1e 317 SMART SM00244 22 179 5.0E-72 T 23-10-2018 IPR001107 Band 7 domain A0127_08450 1dee7694254bfddd6a06be1172d51b1e 317 ProSitePatterns PS01270 Band 7 protein family signature. 135 163 - T 23-10-2018 IPR018080 Band 7/stomatin-like, conserved site A0127_08450 1dee7694254bfddd6a06be1172d51b1e 317 Gene3D G3DSA:3.30.479.30 50 181 4.2E-52 T 23-10-2018 A0127_04020 988c748ab8ae946a853e9316e543f1b2 135 SUPERFAMILY SSF143870 2 127 5.49E-24 T 23-10-2018 IPR036504 CGI121/TPRKB superfamily Reactome: R-HSA-6782315 A0127_04020 988c748ab8ae946a853e9316e543f1b2 135 Gene3D G3DSA:3.30.2380.10 5 135 2.2E-38 T 23-10-2018 IPR036504 CGI121/TPRKB superfamily Reactome: R-HSA-6782315 A0127_01465 652550e2cde54b9c8089db015faea759 315 Gene3D G3DSA:3.20.20.70 19 264 2.1E-20 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A0127_01465 652550e2cde54b9c8089db015faea759 315 SUPERFAMILY SSF102114 25 220 2.49E-22 T 23-10-2018 A0127_01465 652550e2cde54b9c8089db015faea759 315 SMART SM00729 15 228 0.0012 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A0127_01465 652550e2cde54b9c8089db015faea759 315 Pfam PF04055 Radical SAM superfamily 25 192 1.4E-13 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A0127_04115 28e785e93fdd7aa7939c67cf8bed643f 371 Gene3D G3DSA:1.20.1250.20 1 185 8.5E-42 T 23-10-2018 A0127_04115 28e785e93fdd7aa7939c67cf8bed643f 371 Pfam PF07690 Major Facilitator Superfamily 11 330 2.0E-45 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A0127_04115 28e785e93fdd7aa7939c67cf8bed643f 371 SUPERFAMILY SSF103473 2 364 2.88E-70 T 23-10-2018 IPR036259 MFS transporter superfamily A0127_04115 28e785e93fdd7aa7939c67cf8bed643f 371 Gene3D G3DSA:1.20.1250.20 193 369 4.2E-26 T 23-10-2018 A0127_09505 9f1592782b8451cd0234dccf835f04ec 193 Hamap MF_00316 Molybdenum cofactor guanylyltransferase [mobA]. 1 188 20.679 T 23-10-2018 IPR013482 Molybdenum cofactor guanylyltransferase GO:0003824|GO:0006777 KEGG: 00790+2.7.7.77|MetaCyc: PWY-5964|MetaCyc: PWY-7639 A0127_09505 9f1592782b8451cd0234dccf835f04ec 193 Gene3D G3DSA:3.90.550.10 4 192 3.5E-45 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A0127_09505 9f1592782b8451cd0234dccf835f04ec 193 SUPERFAMILY SSF53448 1 185 8.23E-31 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A0127_09505 9f1592782b8451cd0234dccf835f04ec 193 Pfam PF12804 MobA-like NTP transferase domain 3 156 7.9E-29 T 23-10-2018 IPR025877 MobA-like NTP transferase A0127_08600 38883e9ed30e0a486bc64bb99380533c 288 SUPERFAMILY SSF103481 45 144 1.57E-12 T 23-10-2018 A0127_08600 38883e9ed30e0a486bc64bb99380533c 288 Pfam PF00892 EamA-like transporter family 152 287 3.3E-23 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A0127_08600 38883e9ed30e0a486bc64bb99380533c 288 Pfam PF00892 EamA-like transporter family 5 140 3.8E-23 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A0127_08600 38883e9ed30e0a486bc64bb99380533c 288 SUPERFAMILY SSF103481 192 287 2.22E-12 T 23-10-2018 A0127_05160 15487352db03cd3e6f0bff66d1c6ab49 203 Gene3D G3DSA:3.40.50.11570 1 200 2.3E-37 T 23-10-2018 A0127_05160 15487352db03cd3e6f0bff66d1c6ab49 203 Pfam PF03192 Pyrococcus protein of unknown function, DUF257 12 174 2.2E-30 T 23-10-2018 IPR005489 Protein of unknown function DUF257 A0127_08330 d0e00a9ab5230b6a5a3b3e5761dd3c66 1496 Pfam PF00082 Subtilase family 155 662 2.7E-50 T 23-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 A0127_08330 d0e00a9ab5230b6a5a3b3e5761dd3c66 1496 Gene3D G3DSA:3.40.50.200 380 679 2.1E-65 T 23-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 A0127_08330 d0e00a9ab5230b6a5a3b3e5761dd3c66 1496 SUPERFAMILY SSF52743 135 671 8.51E-60 T 23-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 A0127_08330 d0e00a9ab5230b6a5a3b3e5761dd3c66 1496 Gene3D G3DSA:3.40.50.200 138 224 1.0E-5 T 23-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 A0127_08330 d0e00a9ab5230b6a5a3b3e5761dd3c66 1496 PRINTS PR00723 Subtilisin serine protease family (S8) signature 608 624 4.2E-15 T 23-10-2018 IPR015500 Peptidase S8, subtilisin-related A0127_08330 d0e00a9ab5230b6a5a3b3e5761dd3c66 1496 PRINTS PR00723 Subtilisin serine protease family (S8) signature 414 427 4.2E-15 T 23-10-2018 IPR015500 Peptidase S8, subtilisin-related A0127_08330 d0e00a9ab5230b6a5a3b3e5761dd3c66 1496 PRINTS PR00723 Subtilisin serine protease family (S8) signature 155 174 4.2E-15 T 23-10-2018 IPR015500 Peptidase S8, subtilisin-related A0127_08330 d0e00a9ab5230b6a5a3b3e5761dd3c66 1496 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 418 428 - T 23-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site A0127_08330 d0e00a9ab5230b6a5a3b3e5761dd3c66 1496 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 609 619 - T 23-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site A0127_04335 d1fd312b745ea53b16aaaae869475503 262 SUPERFAMILY SSF53213 6 259 4.71E-25 T 23-10-2018 A0127_04335 d1fd312b745ea53b16aaaae869475503 262 Gene3D G3DSA:3.40.830.10 1 262 2.4E-72 T 23-10-2018 A0127_04335 d1fd312b745ea53b16aaaae869475503 262 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 7 254 9.2E-16 T 23-10-2018 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 A0127_01910 35bb695f533675132077b74be68d5b73 91 Pfam PF01918 Alba 6 66 2.5E-21 T 23-10-2018 IPR002775 DNA/RNA-binding protein Alba-like GO:0003676 A0127_01910 35bb695f533675132077b74be68d5b73 91 ProDom PD010497 ALBA DNA-BINDING DNA/RNA-BINDING RNA-BINDING ACETYLATION 3D-STRUCTURE DNA CONDENSATION AF1 SSO10B 8 90 7.0E-33 T 23-10-2018 A0127_01910 35bb695f533675132077b74be68d5b73 91 SUPERFAMILY SSF82704 5 90 3.01E-27 T 23-10-2018 IPR036882 Alba-like domain superfamily GO:0003676 A0127_01910 35bb695f533675132077b74be68d5b73 91 Hamap MF_01122 DNA/RNA-binding protein Alba [albA]. 1 90 27.999 T 23-10-2018 IPR013795 DNA/RNA-binding protein Alba GO:0003677|GO:0003723|GO:0005737 A0127_01910 35bb695f533675132077b74be68d5b73 91 Gene3D G3DSA:3.30.110.20 2 90 2.7E-38 T 23-10-2018 IPR036882 Alba-like domain superfamily GO:0003676 A0127_01910 35bb695f533675132077b74be68d5b73 91 PIRSF PIRSF028732 1 91 4.4E-40 T 23-10-2018 IPR013795 DNA/RNA-binding protein Alba GO:0003677|GO:0003723|GO:0005737 A0127_01910 35bb695f533675132077b74be68d5b73 91 TIGRFAM TIGR00285 TIGR00285: DNA-binding protein Alba 4 90 7.0E-46 T 23-10-2018 IPR013795 DNA/RNA-binding protein Alba GO:0003677|GO:0003723|GO:0005737 A0127_07265 e412640f63f30acfc65f74372c277af9 301 SUPERFAMILY SSF82866 116 293 5.62E-24 T 23-10-2018 A0127_07265 e412640f63f30acfc65f74372c277af9 301 Hamap MF_01464_A Protein-export membrane protein SecF [secF]. 27 300 25.546 T 23-10-2018 IPR024921 Protein-export membrane protein SecF, archaeal GO:0016021|GO:0065002 A0127_07265 e412640f63f30acfc65f74372c277af9 301 Gene3D G3DSA:1.20.1640.10 119 298 4.1E-13 T 23-10-2018 A0127_07265 e412640f63f30acfc65f74372c277af9 301 Pfam PF02355 Protein export membrane protein 130 295 8.7E-32 T 23-10-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial A0127_00455 c0a81fa80aa3502abaebc622439f219f 324 SUPERFAMILY SSF54211 1 149 1.82E-18 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A0127_00455 c0a81fa80aa3502abaebc622439f219f 324 Pfam PF00288 GHMP kinases N terminal domain 76 136 2.4E-6 T 23-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 A0127_00455 c0a81fa80aa3502abaebc622439f219f 324 PIRSF PIRSF004884 1 309 1.9E-101 T 23-10-2018 IPR004422 GHMP kinase group 1 KEGG: 00790+2.4.2.54|MetaCyc: PWY-6148 A0127_00455 c0a81fa80aa3502abaebc622439f219f 324 TIGRFAM TIGR00144 beta_RFAP_syn: beta-ribofuranosylaminobenzene 5'-phosphate synthase family 2 307 3.1E-49 T 23-10-2018 IPR004422 GHMP kinase group 1 KEGG: 00790+2.4.2.54|MetaCyc: PWY-6148 A0127_00455 c0a81fa80aa3502abaebc622439f219f 324 Gene3D G3DSA:3.30.230.10 16 142 1.3E-9 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A0127_00995 c489965babcd45a040afa08e9103fc90 570 SUPERFAMILY SSF52518 201 449 1.08E-66 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold A0127_00995 c489965babcd45a040afa08e9103fc90 570 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 16 177 3.0E-32 T 23-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 A0127_00995 c489965babcd45a040afa08e9103fc90 570 TIGRFAM TIGR03710 OAFO_sf: 2-oxoacid:acceptor oxidoreductase, alpha subunit 7 564 4.0E-206 T 23-10-2018 IPR022367 2-oxoacid:acceptor oxidoreductase, alpha subunit KEGG: 00020+1.2.7.3|KEGG: 00720+1.2.7.3|MetaCyc: PWY-5392|MetaCyc: PWY-6969 A0127_00995 c489965babcd45a040afa08e9103fc90 570 Gene3D G3DSA:3.40.920.10 6 186 3.0E-26 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 A0127_00995 c489965babcd45a040afa08e9103fc90 570 SUPERFAMILY SSF52922 463 568 2.09E-13 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A0127_00995 c489965babcd45a040afa08e9103fc90 570 Gene3D G3DSA:3.40.50.920 459 570 2.1E-26 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A0127_00995 c489965babcd45a040afa08e9103fc90 570 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 213 445 1.5E-59 T 23-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 A0127_00995 c489965babcd45a040afa08e9103fc90 570 SUPERFAMILY SSF53323 8 222 7.06E-40 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 A0127_00995 c489965babcd45a040afa08e9103fc90 570 Gene3D G3DSA:3.40.50.970 187 389 2.8E-72 T 23-10-2018 A0127_05130 68969d31d1bcf71bf483481d81029589 164 TIGRFAM TIGR02228 sigpep_I_arch: signal peptidase I 3 155 1.6E-39 T 23-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 A0127_05130 68969d31d1bcf71bf483481d81029589 164 SUPERFAMILY SSF51306 35 89 4.45E-10 T 23-10-2018 IPR036286 LexA/Signal peptidase-like superfamily A0127_05130 68969d31d1bcf71bf483481d81029589 164 Pfam PF00717 Peptidase S24-like 38 86 1.3E-6 T 23-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C A0127_05130 68969d31d1bcf71bf483481d81029589 164 PRINTS PR00728 Eukaryotic signal peptidase (S26B) family signature 101 112 3.9E-9 T 23-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 A0127_05130 68969d31d1bcf71bf483481d81029589 164 PRINTS PR00728 Eukaryotic signal peptidase (S26B) family signature 38 53 3.9E-9 T 23-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 A0127_09575 941ca4eec9645398c436ac80c55ae81e 129 SUPERFAMILY SSF53146 1 110 4.32E-32 T 23-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily A0127_09575 941ca4eec9645398c436ac80c55ae81e 129 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 14 103 1.2E-21 T 23-10-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis A0127_09575 941ca4eec9645398c436ac80c55ae81e 129 Gene3D G3DSA:3.30.420.130 1 104 6.3E-31 T 23-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily A0127_01490 d68f5f87163122245fa05f520b329155 440 SUPERFAMILY SSF111283 3 436 4.19E-95 T 23-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 A0127_01490 d68f5f87163122245fa05f520b329155 440 Gene3D G3DSA:3.30.2290.10 3 209 5.6E-18 T 23-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal A0127_01490 d68f5f87163122245fa05f520b329155 440 Pfam PF01523 Putative modulator of DNA gyrase 22 303 7.8E-50 T 23-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 A0127_03970 27b404b52e1da721c2d7b316405a8262 432 Gene3D G3DSA:3.90.550.10 4 220 1.4E-54 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A0127_03970 27b404b52e1da721c2d7b316405a8262 432 SUPERFAMILY SSF53448 5 221 2.05E-33 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A0127_03970 27b404b52e1da721c2d7b316405a8262 432 Gene3D G3DSA:1.20.120.1760 230 426 3.4E-57 T 23-10-2018 A0127_03970 27b404b52e1da721c2d7b316405a8262 432 Pfam PF12804 MobA-like NTP transferase domain 6 115 3.3E-15 T 23-10-2018 IPR025877 MobA-like NTP transferase A0127_03970 27b404b52e1da721c2d7b316405a8262 432 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 295 317 - T 23-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 A0127_03970 27b404b52e1da721c2d7b316405a8262 432 Pfam PF01066 CDP-alcohol phosphatidyltransferase 254 317 2.5E-10 T 23-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 A0127_10095 143a97ad1f74808ce97b0e7584fc4fd8 205 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 33 49 4.4E-5 T 23-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A0127_10095 143a97ad1f74808ce97b0e7584fc4fd8 205 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 19 33 4.4E-5 T 23-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 A0127_10095 143a97ad1f74808ce97b0e7584fc4fd8 205 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 3 19 9.7E-12 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A0127_10095 143a97ad1f74808ce97b0e7584fc4fd8 205 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 30 49 9.7E-12 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A0127_10095 143a97ad1f74808ce97b0e7584fc4fd8 205 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 19 30 9.7E-12 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A0127_10095 143a97ad1f74808ce97b0e7584fc4fd8 205 Pfam PF13412 Winged helix-turn-helix DNA-binding 4 50 2.2E-14 T 23-10-2018 A0127_10095 143a97ad1f74808ce97b0e7584fc4fd8 205 Gene3D G3DSA:1.10.10.10 1 54 6.0E-21 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A0127_10095 143a97ad1f74808ce97b0e7584fc4fd8 205 SMART SM00746 143 179 5.6E-10 T 23-10-2018 IPR011017 TRASH domain A0127_10095 143a97ad1f74808ce97b0e7584fc4fd8 205 SMART SM00344 3 102 9.1E-19 T 23-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A0127_10095 143a97ad1f74808ce97b0e7584fc4fd8 205 Pfam PF08394 Archaeal TRASH domain 143 179 5.6E-20 T 23-10-2018 IPR013603 TRASH transcription regulator C-terminal, archaeal A0127_10095 143a97ad1f74808ce97b0e7584fc4fd8 205 SUPERFAMILY SSF46785 2 60 4.62E-15 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A0127_01970 23f9a117fb9ad7cf4dee5f395420973d 218 Gene3D G3DSA:3.60.21.10 1 214 1.1E-43 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like A0127_01970 23f9a117fb9ad7cf4dee5f395420973d 218 SUPERFAMILY SSF56300 1 207 2.11E-70 T 23-10-2018 A0127_01970 23f9a117fb9ad7cf4dee5f395420973d 218 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 1 205 1.2E-21 T 23-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 A0127_01970 23f9a117fb9ad7cf4dee5f395420973d 218 TIGRFAM TIGR00040 yfcE: phosphodiesterase, MJ0936 family 1 192 5.9E-16 T 23-10-2018 IPR000979 Phosphodiesterase MJ0936/Vps29 Reactome: R-HSA-3238698 A0127_06310 715adacdbfdcc66945d6338e2a8c3b9e 247 Gene3D G3DSA:3.40.50.150 66 246 2.5E-42 T 23-10-2018 A0127_06310 715adacdbfdcc66945d6338e2a8c3b9e 247 Pfam PF05971 Protein of unknown function (DUF890) 19 164 8.8E-8 T 23-10-2018 IPR010286 Ribosomal RNA large subunit methyltransferase F-like GO:0008168 A0127_06310 715adacdbfdcc66945d6338e2a8c3b9e 247 SUPERFAMILY SSF53335 8 233 2.17E-24 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A0127_03860 2301ccc9a4a970004584748887ba86a6 547 SUPERFAMILY SSF48592 17 524 2.09E-93 T 23-10-2018 IPR027413 GroEL-like equatorial domain superfamily A0127_03860 2301ccc9a4a970004584748887ba86a6 547 ProSitePatterns PS00751 Chaperonins TCP-1 signature 2. 61 77 - T 23-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 A0127_03860 2301ccc9a4a970004584748887ba86a6 547 ProSitePatterns PS00750 Chaperonins TCP-1 signature 1. 40 52 - T 23-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 A0127_03860 2301ccc9a4a970004584748887ba86a6 547 Gene3D G3DSA:3.50.7.10 218 369 3.6E-216 T 23-10-2018 IPR027409 GroEL-like apical domain superfamily A0127_03860 2301ccc9a4a970004584748887ba86a6 547 Gene3D G3DSA:3.30.260.10 147 405 3.6E-216 T 23-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily A0127_03860 2301ccc9a4a970004584748887ba86a6 547 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 89 108 8.4E-35 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 A0127_03860 2301ccc9a4a970004584748887ba86a6 547 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 37 53 8.4E-35 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 A0127_03860 2301ccc9a4a970004584748887ba86a6 547 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 407 419 8.4E-35 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 A0127_03860 2301ccc9a4a970004584748887ba86a6 547 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 59 77 8.4E-35 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 A0127_03860 2301ccc9a4a970004584748887ba86a6 547 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 373 395 8.4E-35 T 23-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 A0127_03860 2301ccc9a4a970004584748887ba86a6 547 Gene3D G3DSA:1.10.560.10 28 522 3.6E-216 T 23-10-2018 IPR027413 GroEL-like equatorial domain superfamily A0127_03860 2301ccc9a4a970004584748887ba86a6 547 SUPERFAMILY SSF54849 146 404 3.66E-30 T 23-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily A0127_03860 2301ccc9a4a970004584748887ba86a6 547 Pfam PF00118 TCP-1/cpn60 chaperonin family 35 525 3.1E-186 T 23-10-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 A0127_03860 2301ccc9a4a970004584748887ba86a6 547 SUPERFAMILY SSF52029 212 378 3.77E-64 T 23-10-2018 IPR027409 GroEL-like apical domain superfamily A0127_03860 2301ccc9a4a970004584748887ba86a6 547 TIGRFAM TIGR02339 thermosome_arch: thermosome, various subunits, archaeal 8 524 3.7E-246 T 23-10-2018 IPR012714 Thermosome, archaeal GO:0005524|GO:0006457|GO:0051082 A0127_03860 2301ccc9a4a970004584748887ba86a6 547 ProSitePatterns PS00995 Chaperonins TCP-1 signature 3. 89 97 - T 23-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 A0127_00870 c4ed5cfc41308e73b3453b2d3e603231 230 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 133 161 - T 23-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 A0127_00870 c4ed5cfc41308e73b3453b2d3e603231 230 Gene3D G3DSA:3.40.50.720 1 230 5.2E-66 T 23-10-2018 A0127_00870 c4ed5cfc41308e73b3453b2d3e603231 230 SUPERFAMILY SSF51735 2 212 5.99E-57 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A0127_00870 c4ed5cfc41308e73b3453b2d3e603231 230 Pfam PF00106 short chain dehydrogenase 2 184 2.0E-43 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A0127_00870 c4ed5cfc41308e73b3453b2d3e603231 230 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 74 85 1.7E-20 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A0127_00870 c4ed5cfc41308e73b3453b2d3e603231 230 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 1.7E-20 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A0127_00870 c4ed5cfc41308e73b3453b2d3e603231 230 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 182 1.7E-20 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A0127_00870 c4ed5cfc41308e73b3453b2d3e603231 230 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 146 165 1.7E-20 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A0127_00870 c4ed5cfc41308e73b3453b2d3e603231 230 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 120 136 1.7E-20 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A0127_09255 754b0e4efe0a4e283fdf7863fa26d259 324 SMART SM00729 17 247 5.7E-25 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A0127_09255 754b0e4efe0a4e283fdf7863fa26d259 324 TIGRFAM TIGR01210 TIGR01210: radical SAM enzyme, TIGR01210 family 3 321 6.1E-126 T 23-10-2018 IPR005909 Conserved hypothetical protein CHP01210 A0127_09255 754b0e4efe0a4e283fdf7863fa26d259 324 Pfam PF04055 Radical SAM superfamily 35 180 1.2E-8 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A0127_09255 754b0e4efe0a4e283fdf7863fa26d259 324 PIRSF PIRSF004954 1 318 3.7E-101 T 23-10-2018 IPR005909 Conserved hypothetical protein CHP01210 A0127_09255 754b0e4efe0a4e283fdf7863fa26d259 324 SUPERFAMILY SSF102114 16 255 3.53E-15 T 23-10-2018 A0127_07155 b797d6219cbca53e3fcdc5d9f6e6e9f1 154 ProSitePatterns PS01099 Respiratory-chain NADH dehydrogenase 24 Kd subunit signature. 105 123 - T 23-10-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A0127_07155 b797d6219cbca53e3fcdc5d9f6e6e9f1 154 Gene3D G3DSA:3.40.30.10 66 153 1.0E-32 T 23-10-2018 A0127_07155 b797d6219cbca53e3fcdc5d9f6e6e9f1 154 TIGRFAM TIGR01958 nuoE_fam: NADH-quinone oxidoreductase, E subunit 8 147 2.9E-44 T 23-10-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A0127_07155 b797d6219cbca53e3fcdc5d9f6e6e9f1 154 SUPERFAMILY SSF52833 7 151 6.82E-54 T 23-10-2018 IPR036249 Thioredoxin-like superfamily A0127_07155 b797d6219cbca53e3fcdc5d9f6e6e9f1 154 PIRSF PIRSF000216 6 154 5.7E-60 T 23-10-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A0127_07155 b797d6219cbca53e3fcdc5d9f6e6e9f1 154 Gene3D G3DSA:1.10.10.1590 5 65 1.9E-20 T 23-10-2018 A0127_07155 b797d6219cbca53e3fcdc5d9f6e6e9f1 154 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 7 147 3.0E-54 T 23-10-2018 A0127_08790 a96f9f550fb63c5d7a99221f55861f87 166 Pfam PF01842 ACT domain 105 158 1.9E-7 T 23-10-2018 IPR002912 ACT domain A0127_08790 a96f9f550fb63c5d7a99221f55861f87 166 Gene3D G3DSA:3.30.70.260 104 165 2.8E-5 T 23-10-2018 A0127_08790 a96f9f550fb63c5d7a99221f55861f87 166 SUPERFAMILY SSF55021 105 164 9.16E-9 T 23-10-2018 A0127_08790 a96f9f550fb63c5d7a99221f55861f87 166 PIRSF PIRSF004897 1 166 9.3E-70 T 23-10-2018 IPR014424 Uncharacterised conserved protein UCP004897, ACT- type A0127_03320 bf288efc451d3f4ddb8cc31823478720 180 Pfam PF01381 Helix-turn-helix 96 143 2.0E-6 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A0127_03320 bf288efc451d3f4ddb8cc31823478720 180 SMART SM00530 91 146 2.2E-5 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A0127_03320 bf288efc451d3f4ddb8cc31823478720 180 SUPERFAMILY SSF47413 81 144 2.76E-7 T 23-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A0127_03320 bf288efc451d3f4ddb8cc31823478720 180 TIGRFAM TIGR00270 TIGR00270: TIGR00270 family protein 8 173 2.6E-22 T 23-10-2018 IPR004451 Conserved hypothetical protein CHP00270 A0127_03320 bf288efc451d3f4ddb8cc31823478720 180 Gene3D G3DSA:1.10.260.40 80 180 2.2E-11 T 23-10-2018 A0127_02350 7f8d99c941110e79f00212603727f3f8 406 SUPERFAMILY SSF51366 2 214 2.5E-45 T 23-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 A0127_02350 7f8d99c941110e79f00212603727f3f8 406 TIGRFAM TIGR03128 RuMP_HxlA: 3-hexulose-6-phosphate synthase 3 206 1.1E-84 T 23-10-2018 IPR017553 3-hexulose-6-phosphate synthase GO:0005975|GO:0043801 KEGG: 00030+4.1.2.43|KEGG: 00680+4.1.2.43|MetaCyc: PWY-1861|MetaCyc: PWY-7796 A0127_02350 7f8d99c941110e79f00212603727f3f8 406 Gene3D G3DSA:3.20.20.70 1 208 2.9E-76 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A0127_02350 7f8d99c941110e79f00212603727f3f8 406 TIGRFAM TIGR03127 RuMP_HxlB: 6-phospho 3-hexuloisomerase 219 406 3.1E-76 T 23-10-2018 IPR017552 3-hexulose-6-phosphate isomerase GO:0016853 A0127_02350 7f8d99c941110e79f00212603727f3f8 406 SMART SM00934 2 203 3.2E-45 T 23-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A0127_02350 7f8d99c941110e79f00212603727f3f8 406 SUPERFAMILY SSF53697 215 404 1.6E-40 T 23-10-2018 A0127_02350 7f8d99c941110e79f00212603727f3f8 406 Gene3D G3DSA:3.40.50.10490 213 406 1.9E-59 T 23-10-2018 A0127_02350 7f8d99c941110e79f00212603727f3f8 406 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 3 203 3.2E-28 T 23-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A0127_02350 7f8d99c941110e79f00212603727f3f8 406 Pfam PF01380 SIS domain 246 347 4.1E-21 T 23-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 A0127_09870 0a6c295684db132c2306d20c1e6ac1f6 412 Hamap MF_02096 DNA repair protein. 1 406 40.096 T 23-10-2018 IPR033167 Archaeal Nre GO:0006281 A0127_09870 0a6c295684db132c2306d20c1e6ac1f6 412 Pfam PF04895 Archaeal Nre, C-terminal 296 406 4.3E-38 T 23-10-2018 IPR006979 Archaeal Nre, C-terminal A0127_09870 0a6c295684db132c2306d20c1e6ac1f6 412 Pfam PF04894 Archaeal Nre, N-terminal 19 284 1.9E-103 T 23-10-2018 IPR006978 Archaeal Nre, N-terminal A0127_02215 367cd27df6f82eee033c657fecb85e5f 190 PIRSF PIRSF000498 8 190 8.3E-53 T 23-10-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A0127_02215 367cd27df6f82eee033c657fecb85e5f 190 Pfam PF00677 Lumazine binding domain 29 80 1.4E-11 T 23-10-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A0127_02215 367cd27df6f82eee033c657fecb85e5f 190 Pfam PF00677 Lumazine binding domain 93 176 6.8E-22 T 23-10-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A0127_02215 367cd27df6f82eee033c657fecb85e5f 190 Gene3D G3DSA:2.40.30.20 95 190 2.1E-29 T 23-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A0127_02215 367cd27df6f82eee033c657fecb85e5f 190 SUPERFAMILY SSF63380 86 187 1.87E-28 T 23-10-2018 IPR017938 Riboflavin synthase-like beta-barrel A0127_02215 367cd27df6f82eee033c657fecb85e5f 190 Gene3D G3DSA:2.40.30.20 7 81 4.1E-14 T 23-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A0127_02215 367cd27df6f82eee033c657fecb85e5f 190 TIGRFAM TIGR00187 ribE: riboflavin synthase, alpha subunit 32 187 6.3E-48 T 23-10-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 A0127_02215 367cd27df6f82eee033c657fecb85e5f 190 SUPERFAMILY SSF63380 25 82 8.5E-13 T 23-10-2018 IPR017938 Riboflavin synthase-like beta-barrel A0127_05290 9d91d81ff144d9b87ba5a1db98e90f10 367 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 312 323 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A0127_05290 9d91d81ff144d9b87ba5a1db98e90f10 367 SUPERFAMILY SSF54862 230 327 7.95E-12 T 23-10-2018 A0127_05290 9d91d81ff144d9b87ba5a1db98e90f10 367 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 233 244 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A0127_05290 9d91d81ff144d9b87ba5a1db98e90f10 367 Pfam PF17179 4Fe-4S dicluster domain 233 326 1.3E-27 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A0127_02100 5e4330c427df21ad2e3080f9f294c364 117 TIGRFAM TIGR02338 gimC_beta: prefoldin, beta subunit 4 112 2.1E-40 T 23-10-2018 IPR012713 Prefoldin subunit beta GO:0006457|GO:0016272|GO:0051082 A0127_02100 5e4330c427df21ad2e3080f9f294c364 117 Pfam PF01920 Prefoldin subunit 9 111 4.5E-26 T 23-10-2018 IPR002777 Prefoldin beta-like GO:0006457|GO:0016272|GO:0051082 Reactome: R-HSA-389957 A0127_02100 5e4330c427df21ad2e3080f9f294c364 117 Hamap MF_00307 Prefoldin subunit beta [pfdB]. 1 117 51.594 T 23-10-2018 IPR012713 Prefoldin subunit beta GO:0006457|GO:0016272|GO:0051082 A0127_02100 5e4330c427df21ad2e3080f9f294c364 117 Gene3D G3DSA:1.10.287.370 1 117 1.3E-41 T 23-10-2018 IPR009053 Prefoldin A0127_02100 5e4330c427df21ad2e3080f9f294c364 117 SUPERFAMILY SSF46579 6 110 1.57E-24 T 23-10-2018 A0127_07960 4b6af9bf981457db16c773f4ea2306ab 519 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 182 199 4.0E-12 T 23-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 A0127_07960 4b6af9bf981457db16c773f4ea2306ab 519 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 13 34 4.0E-12 T 23-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 A0127_07960 4b6af9bf981457db16c773f4ea2306ab 519 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 42 61 4.0E-12 T 23-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 A0127_07960 4b6af9bf981457db16c773f4ea2306ab 519 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 338 357 4.0E-12 T 23-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 A0127_07960 4b6af9bf981457db16c773f4ea2306ab 519 SUPERFAMILY SSF161070 5 492 4.18E-100 T 23-10-2018 IPR037272 Sodium:neurotransmitter symporter superfamily GO:0005328 A0127_07960 4b6af9bf981457db16c773f4ea2306ab 519 Pfam PF00209 Sodium:neurotransmitter symporter family 145 494 2.2E-22 T 23-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 A0127_07960 4b6af9bf981457db16c773f4ea2306ab 519 Pfam PF00209 Sodium:neurotransmitter symporter family 5 131 2.4E-19 T 23-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 A0127_05535 e6257292d59f9ae067ebcaedd049d051 304 SUPERFAMILY SSF117070 161 256 3.14E-14 T 23-10-2018 A0127_05535 e6257292d59f9ae067ebcaedd049d051 304 Gene3D G3DSA:2.60.40.10 165 296 3.2E-30 T 23-10-2018 IPR013783 Immunoglobulin-like fold A0127_05535 e6257292d59f9ae067ebcaedd049d051 304 Gene3D G3DSA:2.60.40.10 32 151 2.4E-8 T 23-10-2018 IPR013783 Immunoglobulin-like fold A0127_05535 e6257292d59f9ae067ebcaedd049d051 304 Pfam PF03168 Late embryogenesis abundant protein 188 269 5.0E-12 T 23-10-2018 IPR004864 Late embryogenesis abundant protein, LEA_2 subgroup A0127_05535 e6257292d59f9ae067ebcaedd049d051 304 SMART SM00769 166 281 7.2E-7 T 23-10-2018 IPR013990 Water stress and hypersensitive response domain GO:0009269 A0127_04010 c310df41407ae86b6726ab8a3cb9c951 413 ProSitePatterns PS01135 FtsZ protein signature 2. 121 142 - T 23-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 A0127_04010 c310df41407ae86b6726ab8a3cb9c951 413 SMART SM00865 238 355 2.6E-39 T 23-10-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-380320 A0127_04010 c310df41407ae86b6726ab8a3cb9c951 413 Gene3D G3DSA:3.40.50.1440 27 251 7.6E-69 T 23-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 A0127_04010 c310df41407ae86b6726ab8a3cb9c951 413 Gene3D G3DSA:3.30.1330.20 256 360 1.2E-28 T 23-10-2018 IPR037103 Tubulin/FtsZ, C-terminal domain superfamily Reactome: R-HSA-380320 A0127_04010 c310df41407ae86b6726ab8a3cb9c951 413 SMART SM00864 37 236 2.4E-83 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A0127_04010 c310df41407ae86b6726ab8a3cb9c951 413 SUPERFAMILY SSF52490 36 239 6.02E-56 T 23-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 A0127_04010 c310df41407ae86b6726ab8a3cb9c951 413 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 33 374 33.618 T 23-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 A0127_04010 c310df41407ae86b6726ab8a3cb9c951 413 Pfam PF12327 FtsZ family, C-terminal domain 253 347 9.5E-26 T 23-10-2018 IPR024757 Cell division protein FtsZ, C-terminal A0127_04010 c310df41407ae86b6726ab8a3cb9c951 413 PRINTS PR00423 Cell division protein FtsZ signature 122 142 2.2E-35 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A0127_04010 c310df41407ae86b6726ab8a3cb9c951 413 PRINTS PR00423 Cell division protein FtsZ signature 243 264 2.2E-35 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A0127_04010 c310df41407ae86b6726ab8a3cb9c951 413 PRINTS PR00423 Cell division protein FtsZ signature 158 179 2.2E-35 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A0127_04010 c310df41407ae86b6726ab8a3cb9c951 413 PRINTS PR00423 Cell division protein FtsZ signature 220 242 2.2E-35 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A0127_04010 c310df41407ae86b6726ab8a3cb9c951 413 SUPERFAMILY SSF55307 238 352 7.33E-36 T 23-10-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 A0127_04010 c310df41407ae86b6726ab8a3cb9c951 413 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 30 355 1.1E-111 T 23-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 A0127_04010 c310df41407ae86b6726ab8a3cb9c951 413 ProSitePatterns PS01134 FtsZ protein signature 1. 68 102 - T 23-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 A0127_04010 c310df41407ae86b6726ab8a3cb9c951 413 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 37 205 1.3E-43 T 23-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 A0127_02930 267570b4530bd8852fe302bbd56b7060 277 PIRSF PIRSF006250 4 276 1.2E-91 T 23-10-2018 IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD Reactome: R-HSA-196807 A0127_02930 267570b4530bd8852fe302bbd56b7060 277 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 16 102 2.2E-31 T 23-10-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 A0127_02930 267570b4530bd8852fe302bbd56b7060 277 SUPERFAMILY SSF54675 5 103 8.01E-31 T 23-10-2018 A0127_02930 267570b4530bd8852fe302bbd56b7060 277 Gene3D G3DSA:3.90.1170.20 10 271 4.6E-91 T 23-10-2018 IPR037128 Quinolinate phosphoribosyl transferase, N-terminal domain superfamily GO:0016763 Reactome: R-HSA-196807 A0127_02930 267570b4530bd8852fe302bbd56b7060 277 Gene3D G3DSA:3.20.20.70 120 263 4.6E-91 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A0127_02930 267570b4530bd8852fe302bbd56b7060 277 TIGRFAM TIGR00078 nadC: nicotinate-nucleotide diphosphorylase (carboxylating) 7 273 1.6E-97 T 23-10-2018 IPR004393 Nicotinate-nucleotide pyrophosphorylase GO:0004514|GO:0019363 KEGG: 00760+2.4.2.19|MetaCyc: PWY-5316|MetaCyc: PWY-5653|MetaCyc: PWY-7342|Reactome: R-HSA-196807 A0127_02930 267570b4530bd8852fe302bbd56b7060 277 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 104 272 3.7E-51 T 23-10-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 Reactome: R-HSA-196807 A0127_02930 267570b4530bd8852fe302bbd56b7060 277 SUPERFAMILY SSF51690 104 273 1.02E-48 T 23-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 A0127_07175 c8f81b2d60b26b15dd8981f945fbd811 101 Pfam PF14578 Elongation factor Tu domain 4 22 97 2.5E-18 T 23-10-2018 IPR029459 Elongation factor Tu-type domain A0127_07175 c8f81b2d60b26b15dd8981f945fbd811 101 SUPERFAMILY SSF50447 23 100 1.97E-11 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily A0127_07175 c8f81b2d60b26b15dd8981f945fbd811 101 Gene3D G3DSA:2.40.30.10 14 101 3.0E-18 T 23-10-2018 A0127_00930 e6a321299090275e72d5727f78a28724 178 SUPERFAMILY SSF55469 1 167 1.57E-48 T 23-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A0127_00930 e6a321299090275e72d5727f78a28724 178 Pfam PF00881 Nitroreductase family 7 62 9.0E-18 T 23-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 A0127_00930 e6a321299090275e72d5727f78a28724 178 Pfam PF00881 Nitroreductase family 63 150 1.5E-11 T 23-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 A0127_00930 e6a321299090275e72d5727f78a28724 178 Gene3D G3DSA:3.40.109.10 1 173 8.9E-52 T 23-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A0127_02950 4efb01b529ab31783ed64c58ad5bfeee 449 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 4 442 45.559 T 23-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 A0127_02950 4efb01b529ab31783ed64c58ad5bfeee 449 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 5 442 4.3E-157 T 23-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 A0127_02950 4efb01b529ab31783ed64c58ad5bfeee 449 SUPERFAMILY SSF53271 238 443 1.7E-70 T 23-10-2018 IPR029057 Phosphoribosyltransferase-like A0127_02950 4efb01b529ab31783ed64c58ad5bfeee 449 PIRSF PIRSF000485 1 445 1.4E-159 T 23-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 A0127_02950 4efb01b529ab31783ed64c58ad5bfeee 449 Gene3D G3DSA:3.40.50.2020 263 427 3.6E-144 T 23-10-2018 A0127_02950 4efb01b529ab31783ed64c58ad5bfeee 449 Gene3D G3DSA:3.60.20.10 5 443 3.6E-144 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A0127_02950 4efb01b529ab31783ed64c58ad5bfeee 449 Pfam PF13537 Glutamine amidotransferase domain 72 199 5.8E-18 T 23-10-2018 IPR017932 Glutamine amidotransferase type 2 domain A0127_02950 4efb01b529ab31783ed64c58ad5bfeee 449 Pfam PF00156 Phosphoribosyl transferase domain 326 374 1.0E-9 T 23-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 A0127_02950 4efb01b529ab31783ed64c58ad5bfeee 449 SUPERFAMILY SSF56235 5 245 1.46E-51 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A0127_00015 91cd65cc26f09e38c15ca9713a5e2876 135 Pfam PF09868 Uncharacterized protein conserved in archaea (DUF2095) 8 135 4.1E-76 T 23-10-2018 IPR018662 Protein of unknown function DUF2095 A0127_06870 b8d50141e8f87f8bd549fef5a0a2e07c 194 Gene3D G3DSA:3.40.50.150 15 194 5.1E-40 T 23-10-2018 A0127_06870 b8d50141e8f87f8bd549fef5a0a2e07c 194 SUPERFAMILY SSF53335 3 181 1.35E-40 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A0127_06870 b8d50141e8f87f8bd549fef5a0a2e07c 194 Pfam PF13847 Methyltransferase domain 38 158 2.9E-17 T 23-10-2018 IPR025714 Methyltransferase domain A0127_06870 b8d50141e8f87f8bd549fef5a0a2e07c 194 TIGRFAM TIGR00537 hemK_rel_arch: putative methylase 16 191 3.1E-59 T 23-10-2018 IPR004557 Eukaryotic/archaeal PrmC-related GO:0008276 Reactome: R-HSA-156581|Reactome: R-HSA-72764 A0127_10030 5d96f32458ae0b7ac568d165a9d83538 499 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 278 471 3.5E-6 T 23-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 A0127_10030 5d96f32458ae0b7ac568d165a9d83538 499 Pfam PF00149 Calcineurin-like phosphoesterase 1 184 3.4E-21 T 23-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 A0127_10030 5d96f32458ae0b7ac568d165a9d83538 499 SUPERFAMILY SSF56300 254 485 3.17E-31 T 23-10-2018 A0127_10030 5d96f32458ae0b7ac568d165a9d83538 499 Gene3D G3DSA:3.60.21.10 253 490 2.4E-21 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like A0127_10030 5d96f32458ae0b7ac568d165a9d83538 499 Gene3D G3DSA:3.60.21.10 1 252 1.8E-41 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like A0127_10030 5d96f32458ae0b7ac568d165a9d83538 499 SUPERFAMILY SSF56300 1 234 8.86E-51 T 23-10-2018 A0127_06545 93447d1c8d2740f3af00e0f0e74c4937 443 Pfam PF00884 Sulfatase 3 339 5.3E-24 T 23-10-2018 IPR000917 Sulfatase, N-terminal GO:0008484 A0127_06545 93447d1c8d2740f3af00e0f0e74c4937 443 SUPERFAMILY SSF53649 4 434 1.6E-38 T 23-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 A0127_10335 6552458054066f12ffa157cb7a024274 108 Gene3D G3DSA:3.40.1260.10 1 107 6.9E-14 T 23-10-2018 IPR027396 DsrEFH-like A0127_08430 8ba89a53ea462ebe5fad376703374bc1 123 SUPERFAMILY SSF55315 4 121 1.77E-40 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like A0127_08430 8ba89a53ea462ebe5fad376703374bc1 123 Gene3D G3DSA:3.30.1330.30 1 123 1.5E-43 T 23-10-2018 IPR029064 50S ribosomal protein L30e-like A0127_08430 8ba89a53ea462ebe5fad376703374bc1 123 PRINTS PR00884 Ribosomal protein HS6 signature 50 61 8.5E-32 T 23-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 A0127_08430 8ba89a53ea462ebe5fad376703374bc1 123 PRINTS PR00884 Ribosomal protein HS6 signature 91 107 8.5E-32 T 23-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 A0127_08430 8ba89a53ea462ebe5fad376703374bc1 123 PRINTS PR00884 Ribosomal protein HS6 signature 6 17 8.5E-32 T 23-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 A0127_08430 8ba89a53ea462ebe5fad376703374bc1 123 PRINTS PR00884 Ribosomal protein HS6 signature 40 50 8.5E-32 T 23-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 A0127_08430 8ba89a53ea462ebe5fad376703374bc1 123 PRINTS PR00884 Ribosomal protein HS6 signature 77 87 8.5E-32 T 23-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 A0127_08430 8ba89a53ea462ebe5fad376703374bc1 123 TIGRFAM TIGR03677 eL8_ribo: ribosomal protein eL8 6 121 9.8E-58 T 23-10-2018 IPR022481 Ribosomal protein L7Ae, archaea GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 A0127_08430 8ba89a53ea462ebe5fad376703374bc1 123 PRINTS PR00881 Ribosomal protein L7A/RS6 family signature 32 46 1.4E-22 T 23-10-2018 IPR018492 Ribosomal protein L7Ae/L8/Nhp2 family A0127_08430 8ba89a53ea462ebe5fad376703374bc1 123 PRINTS PR00881 Ribosomal protein L7A/RS6 family signature 67 77 1.4E-22 T 23-10-2018 IPR018492 Ribosomal protein L7Ae/L8/Nhp2 family A0127_08430 8ba89a53ea462ebe5fad376703374bc1 123 PRINTS PR00881 Ribosomal protein L7A/RS6 family signature 77 91 1.4E-22 T 23-10-2018 IPR018492 Ribosomal protein L7Ae/L8/Nhp2 family A0127_08430 8ba89a53ea462ebe5fad376703374bc1 123 PRINTS PR00881 Ribosomal protein L7A/RS6 family signature 51 64 1.4E-22 T 23-10-2018 IPR018492 Ribosomal protein L7Ae/L8/Nhp2 family A0127_08430 8ba89a53ea462ebe5fad376703374bc1 123 Pfam PF01248 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family 18 110 1.7E-32 T 23-10-2018 IPR004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45 A0127_08430 8ba89a53ea462ebe5fad376703374bc1 123 ProSitePatterns PS01082 Ribosomal protein L7Ae signature. 70 87 - T 23-10-2018 IPR004037 Ribosomal protein L7Ae conserved site GO:0042254|GO:1990904 Reactome: R-HSA-6791226 A0127_08430 8ba89a53ea462ebe5fad376703374bc1 123 Hamap MF_00326 50S ribosomal protein L7Ae [rpl7ae]. 3 122 35.709 T 23-10-2018 IPR022481 Ribosomal protein L7Ae, archaea GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 A0127_06330 5f7e08e5645155769844669c6c681e20 133 SUPERFAMILY SSF53335 14 84 3.16E-6 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A0127_06330 5f7e08e5645155769844669c6c681e20 133 ProDom PD021130 UPF0146 MJ0688 SIMILAR ARCHAEA UNCHARACTERIZED AF0739.1 MTH1000 PYRAB01940 PH0209 VNG2609C 19 112 3.0E-34 T 23-10-2018 IPR005353 Uncharacterised protein family UPF0146 A0127_06330 5f7e08e5645155769844669c6c681e20 133 Hamap MF_00341 UPF0146 protein . 3 132 25.7 T 23-10-2018 IPR005353 Uncharacterised protein family UPF0146 A0127_06330 5f7e08e5645155769844669c6c681e20 133 Pfam PF03686 Uncharacterised protein family (UPF0146) 4 132 2.1E-30 T 23-10-2018 IPR005353 Uncharacterised protein family UPF0146 A0127_06330 5f7e08e5645155769844669c6c681e20 133 Gene3D G3DSA:3.40.50.150 1 133 6.5E-24 T 23-10-2018 A0127_00885 27afd3f9c22634f71a9bc965076c368d 200 TIGRFAM TIGR03334 IOR_beta: indolepyruvate ferredoxin oxidoreductase, beta subunit 2 193 1.4E-62 T 23-10-2018 IPR017719 Indolepyruvate ferredoxin oxidoreductase, beta subunit GO:0043805|GO:0055114 A0127_00885 27afd3f9c22634f71a9bc965076c368d 200 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 9 193 1.1E-39 T 23-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 A0127_00885 27afd3f9c22634f71a9bc965076c368d 200 Gene3D G3DSA:3.40.920.10 1 199 9.0E-49 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 A0127_00885 27afd3f9c22634f71a9bc965076c368d 200 SUPERFAMILY SSF53323 2 198 1.28E-41 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 A0127_03710 308006c71346e6a7fe7dbf31ebcbc152 422 Gene3D G3DSA:2.130.10.10 18 394 1.5E-22 T 23-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 A0127_03710 308006c71346e6a7fe7dbf31ebcbc152 422 SUPERFAMILY SSF50998 73 409 1.57E-18 T 23-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily A0127_03710 308006c71346e6a7fe7dbf31ebcbc152 422 SMART SM00564 275 310 44.0 T 23-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat A0127_03710 308006c71346e6a7fe7dbf31ebcbc152 422 SMART SM00564 45 90 12.0 T 23-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat A0127_03710 308006c71346e6a7fe7dbf31ebcbc152 422 SMART SM00564 234 269 420.0 T 23-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat A0127_03710 308006c71346e6a7fe7dbf31ebcbc152 422 SMART SM00564 186 227 11.0 T 23-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat A0127_03710 308006c71346e6a7fe7dbf31ebcbc152 422 SMART SM00564 317 364 36.0 T 23-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat A0127_03710 308006c71346e6a7fe7dbf31ebcbc152 422 Pfam PF13570 PQQ-like domain 303 356 2.4E-7 T 23-10-2018 IPR025666 Pyrrolo-quinoline quinone-like domain A0127_02550 d6fa48cdcbdf5dc9457fdc4ac0be0a6a 503 Gene3D G3DSA:3.40.1030.10 152 412 5.5E-103 T 23-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 A0127_02550 d6fa48cdcbdf5dc9457fdc4ac0be0a6a 503 ProSitePatterns PS00647 Thymidine and pyrimidine-nucleoside phosphorylases signature. 193 208 - T 23-10-2018 IPR017872 Pyrimidine-nucleoside phosphorylase, conserved site GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A0127_02550 d6fa48cdcbdf5dc9457fdc4ac0be0a6a 503 TIGRFAM TIGR03327 AMP_phos: AMP phosphorylase 3 500 1.4E-248 T 23-10-2018 IPR017713 AMP phosphorylase GO:0009032|GO:0046125 MetaCyc: PWY-5532 A0127_02550 d6fa48cdcbdf5dc9457fdc4ac0be0a6a 503 SMART SM00941 424 491 8.8E-25 T 23-10-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A0127_02550 d6fa48cdcbdf5dc9457fdc4ac0be0a6a 503 Gene3D G3DSA:3.90.1170.30 413 493 8.1E-30 T 23-10-2018 IPR036566 Pyrimidine nucleoside phosphorylase-like, C-terminal domain superfamily GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A0127_02550 d6fa48cdcbdf5dc9457fdc4ac0be0a6a 503 Pfam PF02885 Glycosyl transferase family, helical bundle domain 89 150 7.8E-15 T 23-10-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 A0127_02550 d6fa48cdcbdf5dc9457fdc4ac0be0a6a 503 TIGRFAM TIGR02645 ARCH_P_rylase: putative thymidine phosphorylase 4 494 3.4E-231 T 23-10-2018 IPR013466 Thymidine phosphorylase/AMP phosphorylase GO:0016763 A0127_02550 d6fa48cdcbdf5dc9457fdc4ac0be0a6a 503 Pfam PF00591 Glycosyl transferase family, a/b domain 158 386 1.7E-14 T 23-10-2018 IPR000312 Glycosyl transferase, family 3 GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A0127_02550 d6fa48cdcbdf5dc9457fdc4ac0be0a6a 503 SUPERFAMILY SSF52418 155 403 6.28E-70 T 23-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 A0127_02550 d6fa48cdcbdf5dc9457fdc4ac0be0a6a 503 Gene3D G3DSA:2.40.40.20 1 83 8.3E-43 T 23-10-2018 A0127_02550 d6fa48cdcbdf5dc9457fdc4ac0be0a6a 503 PIRSF PIRSF000478 84 502 8.0E-126 T 23-10-2018 IPR000053 Thymidine/pyrimidine-nucleoside phosphorylase GO:0004645|GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A0127_02550 d6fa48cdcbdf5dc9457fdc4ac0be0a6a 503 SUPERFAMILY SSF54680 412 495 1.83E-19 T 23-10-2018 IPR036566 Pyrimidine nucleoside phosphorylase-like, C-terminal domain superfamily GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A0127_02550 d6fa48cdcbdf5dc9457fdc4ac0be0a6a 503 Hamap MF_02132 AMP phosphorylase. 1 503 46.996 T 23-10-2018 IPR017713 AMP phosphorylase GO:0009032|GO:0046125 MetaCyc: PWY-5532 A0127_02550 d6fa48cdcbdf5dc9457fdc4ac0be0a6a 503 Gene3D G3DSA:1.20.970.10 84 151 4.9E-24 T 23-10-2018 A0127_02550 d6fa48cdcbdf5dc9457fdc4ac0be0a6a 503 Pfam PF07831 Pyrimidine nucleoside phosphorylase C-terminal domain 424 487 4.2E-16 T 23-10-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 A0127_02550 d6fa48cdcbdf5dc9457fdc4ac0be0a6a 503 SUPERFAMILY SSF47648 86 153 2.88E-16 T 23-10-2018 IPR036320 Glycosyl transferase family 3, N-terminal domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 A0127_09830 a64bc29f8c5d4a70b401cb3cb0d39c88 145 SUPERFAMILY SSF54814 12 74 2.29E-11 T 23-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 A0127_09830 a64bc29f8c5d4a70b401cb3cb0d39c88 145 Gene3D G3DSA:3.30.300.20 2 73 4.0E-27 T 23-10-2018 IPR015946 K homology domain-like, alpha/beta A0127_09830 a64bc29f8c5d4a70b401cb3cb0d39c88 145 Gene3D G3DSA:3.30.300.20 74 144 2.6E-23 T 23-10-2018 IPR015946 K homology domain-like, alpha/beta A0127_09830 a64bc29f8c5d4a70b401cb3cb0d39c88 145 Pfam PF07650 KH domain 12 94 4.0E-18 T 23-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_09830 a64bc29f8c5d4a70b401cb3cb0d39c88 145 TIGRFAM TIGR01952 nusA_arch: NusA family KH domain protein, archaeal 1 145 1.5E-60 T 23-10-2018 IPR010212 Probable transcription termination protein NusA, archaeal A0127_09830 a64bc29f8c5d4a70b401cb3cb0d39c88 145 SUPERFAMILY SSF54814 76 141 2.68E-7 T 23-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 A0127_09830 a64bc29f8c5d4a70b401cb3cb0d39c88 145 Hamap MF_00945_A Transcription termination/antitermination protein NusA [nusA]. 1 145 30.453 T 23-10-2018 IPR010212 Probable transcription termination protein NusA, archaeal A0127_02140 53d986f94cfadf5c4f74f34a61bc5f9b 76 Pfam PF13244 Domain of unknown function (DUF4040) 12 73 6.4E-10 T 23-10-2018 IPR025383 Domain of unknown function DUF4040 A0127_07530 7767a16d65a32a978b3ffc3676f0200a 121 ProSitePatterns PS01108 Ribosomal protein L24 signature. 49 66 - T 23-10-2018 IPR005825 Ribosomal protein L24/L26, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 A0127_07530 7767a16d65a32a978b3ffc3676f0200a 121 Gene3D G3DSA:2.30.30.30 2 121 2.7E-53 T 23-10-2018 IPR014722 Ribosomal protein L2, domain 2 A0127_07530 7767a16d65a32a978b3ffc3676f0200a 121 Pfam PF00467 KOW motif 48 79 2.3E-9 T 23-10-2018 IPR005824 KOW A0127_07530 7767a16d65a32a978b3ffc3676f0200a 121 SMART SM00739 45 72 4.0E-6 T 23-10-2018 IPR005824 KOW A0127_07530 7767a16d65a32a978b3ffc3676f0200a 121 SUPERFAMILY SSF50104 6 115 1.42E-39 T 23-10-2018 IPR008991 Translation protein SH3-like domain superfamily A0127_07530 7767a16d65a32a978b3ffc3676f0200a 121 TIGRFAM TIGR01080 rplX_A_E: ribosomal protein uL24 6 120 1.1E-58 T 23-10-2018 IPR005756 Ribosomal protein L26/L24, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_07530 7767a16d65a32a978b3ffc3676f0200a 121 Pfam PF16906 Ribosomal proteins L26 eukaryotic, L24P archaeal 6 119 6.3E-37 T 23-10-2018 IPR005756 Ribosomal protein L26/L24, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_07530 7767a16d65a32a978b3ffc3676f0200a 121 Hamap MF_01326_A 50S ribosomal protein L24 [rplX]. 5 118 32.365 T 23-10-2018 IPR005756 Ribosomal protein L26/L24, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_04300 a3e57c389671ec1358af272704eee1a9 460 Pfam PF00149 Calcineurin-like phosphoesterase 1 217 2.7E-15 T 23-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 A0127_04300 a3e57c389671ec1358af272704eee1a9 460 SUPERFAMILY SSF56300 1 338 3.36E-63 T 23-10-2018 A0127_04300 a3e57c389671ec1358af272704eee1a9 460 Hamap MF_02044 DNA double-strand break repair protein Mre11 [mre11]. 1 402 25.215 T 23-10-2018 IPR032885 DNA double-strand break repair protein Mre11, archaea-type GO:0006302 A0127_04300 a3e57c389671ec1358af272704eee1a9 460 Gene3D G3DSA:3.60.21.10 1 280 4.0E-121 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like A0127_04300 a3e57c389671ec1358af272704eee1a9 460 Gene3D G3DSA:3.30.110.80 238 334 4.0E-121 T 23-10-2018 A0127_04960 9db4facb5e8aa2bc770f178c21659a89 156 SMART SM00116 27 73 13.0 T 23-10-2018 IPR000644 CBS domain A0127_04960 9db4facb5e8aa2bc770f178c21659a89 156 SMART SM00116 104 152 2.5E-9 T 23-10-2018 IPR000644 CBS domain A0127_04960 9db4facb5e8aa2bc770f178c21659a89 156 SUPERFAMILY SSF54631 10 151 4.96E-23 T 23-10-2018 A0127_04960 9db4facb5e8aa2bc770f178c21659a89 156 Pfam PF00571 CBS domain 97 151 2.3E-10 T 23-10-2018 IPR000644 CBS domain A0127_04960 9db4facb5e8aa2bc770f178c21659a89 156 Pfam PF00571 CBS domain 23 72 8.3E-7 T 23-10-2018 IPR000644 CBS domain A0127_04960 9db4facb5e8aa2bc770f178c21659a89 156 Gene3D G3DSA:3.10.580.10 20 153 3.4E-22 T 23-10-2018 A0127_00920 7d6b8b02f420ec379caa4c42b5be7722 364 SUPERFAMILY SSF143437 1 161 1.55E-41 T 23-10-2018 A0127_00920 7d6b8b02f420ec379caa4c42b5be7722 364 Gene3D G3DSA:3.30.2130.30 1 162 1.6E-45 T 23-10-2018 A0127_00920 7d6b8b02f420ec379caa4c42b5be7722 364 Pfam PF02926 THUMP domain 25 152 3.4E-23 T 23-10-2018 IPR004114 THUMP domain GO:0003723 A0127_00920 7d6b8b02f420ec379caa4c42b5be7722 364 SMART SM00981 67 153 3.4E-18 T 23-10-2018 IPR004114 THUMP domain GO:0003723 A0127_00920 7d6b8b02f420ec379caa4c42b5be7722 364 Gene3D G3DSA:3.40.50.620 163 361 1.1E-52 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A0127_00920 7d6b8b02f420ec379caa4c42b5be7722 364 Hamap MF_00021 tRNA sulfurtransferase [thiI]. 1 364 107.294 T 23-10-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 KEGG: 00730+2.8.1.4 A0127_00920 7d6b8b02f420ec379caa4c42b5be7722 364 Pfam PF02568 Thiamine biosynthesis protein (ThiI) 163 337 4.4E-51 T 23-10-2018 IPR020536 Thil, AANH domain GO:0004810 KEGG: 00730+2.8.1.4 A0127_00920 7d6b8b02f420ec379caa4c42b5be7722 364 SUPERFAMILY SSF52402 162 362 1.68E-43 T 23-10-2018 A0127_00920 7d6b8b02f420ec379caa4c42b5be7722 364 TIGRFAM TIGR00342 TIGR00342: tRNA sulfurtransferase ThiI 2 335 3.3E-97 T 23-10-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 KEGG: 00730+2.8.1.4 A0127_10205 686b3e20fcff7a1315174f9119d1fcdc 132 PIRSF PIRSF021774 5 132 1.2E-37 T 23-10-2018 IPR016796 Uncharacterised conserved protein UCP021774 A0127_10205 686b3e20fcff7a1315174f9119d1fcdc 132 Gene3D G3DSA:3.30.310.70 5 132 9.0E-41 T 23-10-2018 IPR035923 TT1751-like domain superfamily A0127_10205 686b3e20fcff7a1315174f9119d1fcdc 132 Pfam PF03625 Domain of unknown function DUF302 45 100 3.9E-19 T 23-10-2018 IPR005180 Domain of unknown function DUF302 A0127_10205 686b3e20fcff7a1315174f9119d1fcdc 132 SUPERFAMILY SSF103247 8 131 1.83E-34 T 23-10-2018 IPR035923 TT1751-like domain superfamily A0127_05905 58a82bb2c829292dea640a947ca221d3 111 TIGRFAM TIGR04076 TIGR04076: TIGR04076 family protein 1 96 7.2E-23 T 23-10-2018 IPR023811 Conserved hypothetical protein CHP04076 A0127_09215 b540711177a55d35d7acbceaf477e4a9 142 SMART SM01072 12 74 7.3E-8 T 23-10-2018 IPR004201 CDC48, domain 2 A0127_09215 b540711177a55d35d7acbceaf477e4a9 142 Pfam PF02933 Cell division protein 48 (CDC48), domain 2 14 71 1.4E-6 T 23-10-2018 IPR004201 CDC48, domain 2 A0127_09215 b540711177a55d35d7acbceaf477e4a9 142 Gene3D G3DSA:2.40.10.360 80 141 5.3E-13 T 23-10-2018 A0127_09215 b540711177a55d35d7acbceaf477e4a9 142 Gene3D G3DSA:3.10.330.10 1 78 1.0E-25 T 23-10-2018 A0127_09215 b540711177a55d35d7acbceaf477e4a9 142 SUPERFAMILY SSF54585 2 78 3.6E-14 T 23-10-2018 IPR029067 CDC48 domain 2-like superfamily A0127_06315 ad1197c3b5d07a7dee92f468f9ce0976 421 SUPERFAMILY SSF55031 211 322 1.22E-17 T 23-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain A0127_06315 ad1197c3b5d07a7dee92f468f9ce0976 421 Pfam PF01546 Peptidase family M20/M25/M40 96 419 1.2E-38 T 23-10-2018 IPR002933 Peptidase M20 GO:0016787 A0127_06315 ad1197c3b5d07a7dee92f468f9ce0976 421 TIGRFAM TIGR01910 DapE-ArgE: peptidase, ArgE/DapE family 19 414 1.6E-81 T 23-10-2018 IPR010182 N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine deformylase/Succinyl-diaminopimelate desuccinylase A0127_06315 ad1197c3b5d07a7dee92f468f9ce0976 421 Gene3D G3DSA:3.30.70.360 209 340 2.4E-79 T 23-10-2018 A0127_06315 ad1197c3b5d07a7dee92f468f9ce0976 421 SUPERFAMILY SSF53187 5 419 6.83E-64 T 23-10-2018 A0127_06315 ad1197c3b5d07a7dee92f468f9ce0976 421 Gene3D G3DSA:3.40.630.10 24 409 2.4E-79 T 23-10-2018 A0127_06315 ad1197c3b5d07a7dee92f468f9ce0976 421 Pfam PF07687 Peptidase dimerisation domain 206 316 2.2E-19 T 23-10-2018 IPR011650 Peptidase M20, dimerisation domain A0127_00480 6172ba087ecedeed4103a00cce7acbd3 71 SUPERFAMILY SSF50182 6 71 8.17E-32 T 23-10-2018 IPR010920 LSM domain superfamily A0127_00480 6172ba087ecedeed4103a00cce7acbd3 71 Gene3D G3DSA:2.30.30.100 2 71 1.3E-29 T 23-10-2018 A0127_07425 8190ebe7f80cbefb7fb163bb48023a6e 193 Pfam PF00437 Type II/IV secretion system protein 7 124 1.5E-10 T 23-10-2018 IPR001482 Type II/IV secretion system protein A0127_07425 8190ebe7f80cbefb7fb163bb48023a6e 193 Gene3D G3DSA:3.40.50.300 5 190 7.1E-17 T 23-10-2018 A0127_07425 8190ebe7f80cbefb7fb163bb48023a6e 193 SUPERFAMILY SSF52540 18 169 2.38E-12 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_06620 206fd4ff4036981093a10d693190466b 315 Pfam PF00535 Glycosyl transferase family 2 13 150 8.6E-15 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A0127_06620 206fd4ff4036981093a10d693190466b 315 Gene3D G3DSA:3.90.550.10 10 216 6.7E-25 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A0127_06620 206fd4ff4036981093a10d693190466b 315 SUPERFAMILY SSF53448 13 226 4.22E-32 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A0127_08570 892145b4727ba9580d12cff9b1e22c9e 232 TIGRFAM TIGR00317 cobS: cobalamin 5'-phosphate synthase 2 222 1.3E-47 T 23-10-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 A0127_08570 892145b4727ba9580d12cff9b1e22c9e 232 Pfam PF02654 Cobalamin-5-phosphate synthase 5 221 2.0E-42 T 23-10-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 A0127_08570 892145b4727ba9580d12cff9b1e22c9e 232 Hamap MF_00719 Adenosylcobinamide-GDP ribazoletransferase [cobS]. 1 232 30.674 T 23-10-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 A0127_07270 4cfd55523004e547edd16f4a5cef1487 140 Gene3D G3DSA:3.30.360.110 1 62 8.0E-19 T 23-10-2018 A0127_07270 4cfd55523004e547edd16f4a5cef1487 140 Gene3D G3DSA:3.30.160.750 63 127 7.3E-25 T 23-10-2018 A0127_07270 4cfd55523004e547edd16f4a5cef1487 140 SUPERFAMILY SSF56276 3 117 3.53E-43 T 23-10-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 A0127_07270 4cfd55523004e547edd16f4a5cef1487 140 Pfam PF02675 S-adenosylmethionine decarboxylase 7 113 8.0E-39 T 23-10-2018 IPR003826 S-adenosylmethionine decarboxylase family, prokaryotic GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 A0127_07270 4cfd55523004e547edd16f4a5cef1487 140 TIGRFAM TIGR03330 SAM_DCase_Bsu: S-adenosylmethionine decarboxylase proenzyme 3 113 7.7E-45 T 23-10-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 A0127_07270 4cfd55523004e547edd16f4a5cef1487 140 Hamap MF_00464 S-adenosylmethionine decarboxylase proenzyme [speH]. 1 117 31.447 T 23-10-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 A0127_09230 de0bcea039b9da9b038e13e8b845eeda 153 Pfam PF06146 Phosphate-starvation-inducible E 63 129 8.8E-16 T 23-10-2018 IPR020948 Phosphate-starvation-induced PsiE-like A0127_09635 1afa638b3aee592d7627b9bd41d84f17 107 SUPERFAMILY SSF103473 1 102 4.45E-11 T 23-10-2018 IPR036259 MFS transporter superfamily A0127_09635 1afa638b3aee592d7627b9bd41d84f17 107 Gene3D G3DSA:1.20.1250.20 17 104 2.6E-8 T 23-10-2018 A0127_04965 f38f7624a777746c3ffa7fdf038bd8b0 389 Gene3D G3DSA:1.20.1530.20 2 380 1.9E-85 T 23-10-2018 IPR038770 Sodium/solute symporter superfamily A0127_04965 f38f7624a777746c3ffa7fdf038bd8b0 389 Pfam PF00999 Sodium/hydrogen exchanger family 9 369 5.7E-59 T 23-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 A0127_04700 590e01dc96bcb9ab51cfce494c89c960 356 SUPERFAMILY SSF50249 51 175 1.11E-24 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A0127_04700 590e01dc96bcb9ab51cfce494c89c960 356 Pfam PF08646 Replication factor-A C terminal domain 193 277 5.4E-7 T 23-10-2018 IPR013955 Replication factor A, C-terminal A0127_04700 590e01dc96bcb9ab51cfce494c89c960 356 Pfam PF01336 OB-fold nucleic acid binding domain 73 151 2.9E-11 T 23-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 A0127_04700 590e01dc96bcb9ab51cfce494c89c960 356 Gene3D G3DSA:2.40.50.140 171 345 1.7E-8 T 23-10-2018 A0127_04700 590e01dc96bcb9ab51cfce494c89c960 356 Gene3D G3DSA:2.40.50.140 58 161 2.0E-22 T 23-10-2018 A0127_04700 590e01dc96bcb9ab51cfce494c89c960 356 SUPERFAMILY SSF50249 179 345 7.62E-16 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A0127_01940 fa442c2ef9e24673da7a0b17946bba53 424 Gene3D G3DSA:3.90.600.20 156 251 2.1E-33 T 23-10-2018 A0127_01940 fa442c2ef9e24673da7a0b17946bba53 424 Pfam PF01336 OB-fold nucleic acid binding domain 270 341 1.2E-7 T 23-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 A0127_01940 fa442c2ef9e24673da7a0b17946bba53 424 Pfam PF08489 Domain of unknown function (DUF1743) 140 253 7.8E-36 T 23-10-2018 IPR013696 Domain of unknown function DUF1743 A0127_01940 fa442c2ef9e24673da7a0b17946bba53 424 Hamap MF_01892 tRNA(Ile2) 2-agmatinylcytidine synthetase TiaS [tiaS]. 3 422 36.327 T 23-10-2018 IPR024913 tRNA(Ile2) 2-agmatinylcytidine synthetase TiaS GO:0002101|GO:0016879 A0127_01940 fa442c2ef9e24673da7a0b17946bba53 424 Gene3D G3DSA:2.40.50.1010 252 401 5.8E-42 T 23-10-2018 A0127_01940 fa442c2ef9e24673da7a0b17946bba53 424 Gene3D G3DSA:3.30.70.2200 1 155 9.2E-60 T 23-10-2018 A0127_07745 f6fc167fc514e6f6652c9db0ecdca59c 143 Gene3D G3DSA:1.10.10.10 1 46 3.3E-19 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A0127_07745 f6fc167fc514e6f6652c9db0ecdca59c 143 SMART SM00344 1 102 1.3E-38 T 23-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A0127_07745 f6fc167fc514e6f6652c9db0ecdca59c 143 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 12 23 7.7E-10 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A0127_07745 f6fc167fc514e6f6652c9db0ecdca59c 143 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 23 42 7.7E-10 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A0127_07745 f6fc167fc514e6f6652c9db0ecdca59c 143 Pfam PF01037 Lrp/AsnC ligand binding domain 62 131 1.2E-12 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A0127_07745 f6fc167fc514e6f6652c9db0ecdca59c 143 SUPERFAMILY SSF46785 1 56 3.41E-16 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A0127_07745 f6fc167fc514e6f6652c9db0ecdca59c 143 SUPERFAMILY SSF54909 56 139 6.44E-16 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel A0127_07745 f6fc167fc514e6f6652c9db0ecdca59c 143 Pfam PF13412 Winged helix-turn-helix DNA-binding 2 43 7.8E-17 T 23-10-2018 A0127_07745 f6fc167fc514e6f6652c9db0ecdca59c 143 Gene3D G3DSA:3.30.70.920 48 141 1.2E-21 T 23-10-2018 A0127_05015 3abfde9944f11462766e186bb306b77c 105 Gene3D G3DSA:3.30.70.20 24 73 2.7E-5 T 23-10-2018 A0127_05015 3abfde9944f11462766e186bb306b77c 105 SUPERFAMILY SSF54862 32 102 3.67E-23 T 23-10-2018 A0127_05015 3abfde9944f11462766e186bb306b77c 105 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 83 94 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A0127_05015 3abfde9944f11462766e186bb306b77c 105 Gene3D G3DSA:3.30.70.20 74 105 3.8E-8 T 23-10-2018 A0127_05015 3abfde9944f11462766e186bb306b77c 105 Pfam PF14697 4Fe-4S dicluster domain 48 100 6.9E-11 T 23-10-2018 A0127_05015 3abfde9944f11462766e186bb306b77c 105 TIGRFAM TIGR02179 PorD_KorD: 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate family 29 103 3.4E-34 T 23-10-2018 IPR011898 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate GO:0016625|GO:0051539 A0127_05815 edae17f4010b74e21d9fe631564bc0ba 101 ProDom PD012512 ARCHAEA PH1931 STS176 TA1183 MJ0319 PRECURSOR TVG0378908 UNCHARACTERIZED DUF211 AF1549 12 95 3.0E-41 T 23-10-2018 IPR003831 Protein of unknown function DUF211 A0127_05815 edae17f4010b74e21d9fe631564bc0ba 101 Pfam PF02680 Uncharacterized ArCR, COG1888 5 91 2.8E-38 T 23-10-2018 IPR003831 Protein of unknown function DUF211 A0127_05815 edae17f4010b74e21d9fe631564bc0ba 101 Gene3D G3DSA:3.30.70.1340 1 86 7.2E-35 T 23-10-2018 IPR023129 MTH889-like domain superfamily A0127_05815 edae17f4010b74e21d9fe631564bc0ba 101 SUPERFAMILY SSF160363 4 93 1.83E-34 T 23-10-2018 IPR023129 MTH889-like domain superfamily A0127_00425 6f02fbfb06ac2ca1aacf01f6d89948b5 201 SUPERFAMILY SSF116726 107 190 9.29E-21 T 23-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 A0127_00425 6f02fbfb06ac2ca1aacf01f6d89948b5 201 Pfam PF01895 PhoU domain 19 100 1.8E-8 T 23-10-2018 IPR026022 PhoU domain A0127_00425 6f02fbfb06ac2ca1aacf01f6d89948b5 201 Pfam PF02080 TrkA-C domain 124 190 8.5E-15 T 23-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 A0127_00425 6f02fbfb06ac2ca1aacf01f6d89948b5 201 Gene3D G3DSA:1.20.58.220 7 115 1.2E-19 T 23-10-2018 IPR038078 PhoU-like domain superfamily A0127_00425 6f02fbfb06ac2ca1aacf01f6d89948b5 201 SUPERFAMILY SSF109755 11 112 7.33E-15 T 23-10-2018 A0127_00425 6f02fbfb06ac2ca1aacf01f6d89948b5 201 Gene3D G3DSA:3.30.70.1450 116 201 2.4E-24 T 23-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 A0127_07885 64c36a1e98a0a08b76d88b869421d9ad 967 Hamap MF_00049_A Leucine--tRNA ligase [leuS]. 6 967 18.412 T 23-10-2018 IPR020791 Leucine-tRNA ligase, archaeal GO:0000166|GO:0004823|GO:0005524|GO:0005737|GO:0006429 KEGG: 00970+6.1.1.4 A0127_07885 64c36a1e98a0a08b76d88b869421d9ad 967 SUPERFAMILY SSF50677 209 443 8.37E-31 T 23-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 A0127_07885 64c36a1e98a0a08b76d88b869421d9ad 967 SUPERFAMILY SSF47323 701 910 2.24E-40 T 23-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A0127_07885 64c36a1e98a0a08b76d88b869421d9ad 967 SUPERFAMILY SSF52374 4 694 6.12E-102 T 23-10-2018 A0127_07885 64c36a1e98a0a08b76d88b869421d9ad 967 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 43 54 - T 23-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A0127_07885 64c36a1e98a0a08b76d88b869421d9ad 967 Gene3D G3DSA:3.30.2320.20 835 967 3.6E-49 T 23-10-2018 A0127_07885 64c36a1e98a0a08b76d88b869421d9ad 967 Gene3D G3DSA:1.10.730.10 690 810 8.6E-36 T 23-10-2018 A0127_07885 64c36a1e98a0a08b76d88b869421d9ad 967 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 12 689 9.3E-63 T 23-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 A0127_07885 64c36a1e98a0a08b76d88b869421d9ad 967 Gene3D G3DSA:3.40.50.620 9 688 2.0E-300 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A0127_07885 64c36a1e98a0a08b76d88b869421d9ad 967 Gene3D G3DSA:3.90.740.10 205 451 2.0E-300 T 23-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 A0127_07885 64c36a1e98a0a08b76d88b869421d9ad 967 Gene3D G3DSA:1.10.10.720 866 917 3.6E-49 T 23-10-2018 A0127_07885 64c36a1e98a0a08b76d88b869421d9ad 967 Pfam PF08264 Anticodon-binding domain of tRNA 726 859 5.9E-32 T 23-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 A0127_07885 64c36a1e98a0a08b76d88b869421d9ad 967 TIGRFAM TIGR00395 leuS_arch: leucine--tRNA ligase 7 967 0.0 T 23-10-2018 IPR004493 Leucyl-tRNA synthetase, class Ia, archaeal/eukaryotic cytosolic GO:0000166|GO:0004823|GO:0005524|GO:0005737|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 A0127_07590 f94dba80496cf991ad57b0062a2f2ca2 482 ProSitePatterns PS00755 Protein secY signature 1. 72 91 - T 23-10-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A0127_07590 f94dba80496cf991ad57b0062a2f2ca2 482 ProSitePatterns PS00756 Protein secY signature 2. 178 195 - T 23-10-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A0127_07590 f94dba80496cf991ad57b0062a2f2ca2 482 Gene3D G3DSA:1.10.3370.10 26 482 7.5E-180 T 23-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A0127_07590 f94dba80496cf991ad57b0062a2f2ca2 482 PRINTS PR00303 Preprotein translocase SecY subunit signature 30 48 2.9E-8 T 23-10-2018 A0127_07590 f94dba80496cf991ad57b0062a2f2ca2 482 PRINTS PR00303 Preprotein translocase SecY subunit signature 159 184 2.9E-8 T 23-10-2018 A0127_07590 f94dba80496cf991ad57b0062a2f2ca2 482 PRINTS PR00303 Preprotein translocase SecY subunit signature 446 464 2.9E-8 T 23-10-2018 A0127_07590 f94dba80496cf991ad57b0062a2f2ca2 482 PRINTS PR00303 Preprotein translocase SecY subunit signature 185 208 2.9E-8 T 23-10-2018 A0127_07590 f94dba80496cf991ad57b0062a2f2ca2 482 SUPERFAMILY SSF103491 7 468 2.48E-109 T 23-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A0127_07590 f94dba80496cf991ad57b0062a2f2ca2 482 Pfam PF00344 SecY translocase 72 461 8.3E-71 T 23-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A0127_07590 f94dba80496cf991ad57b0062a2f2ca2 482 Pfam PF10559 Plug domain of Sec61p 38 71 2.6E-11 T 23-10-2018 IPR019561 Translocon Sec61/SecY, plug domain Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A0127_07590 f94dba80496cf991ad57b0062a2f2ca2 482 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 27 470 1.4E-89 T 23-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A0127_07590 f94dba80496cf991ad57b0062a2f2ca2 482 PIRSF PIRSF004557 5 482 1.9E-100 T 23-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A0127_07590 f94dba80496cf991ad57b0062a2f2ca2 482 Hamap MF_01465 Protein translocase subunit SecY [secY]. 17 477 20.859 T 23-10-2018 IPR026593 Protein translocase subunit SecY A0127_09985 28f5d1badded1110cb944158a9c790b5 873 Gene3D G3DSA:3.40.50.880 646 869 2.6E-11 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A0127_09985 28f5d1badded1110cb944158a9c790b5 873 SUPERFAMILY SSF52317 635 872 9.38E-26 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A0127_09985 28f5d1badded1110cb944158a9c790b5 873 Gene3D G3DSA:2.60.40.10 369 467 3.8E-6 T 23-10-2018 IPR013783 Immunoglobulin-like fold A0127_09985 28f5d1badded1110cb944158a9c790b5 873 Pfam PF09822 ABC-type uncharacterized transport system 680 746 2.8E-9 T 23-10-2018 IPR019196 ABC-type uncharacterised transport system Reactome: R-HSA-5610787|Reactome: R-HSA-5620924 A0127_09985 28f5d1badded1110cb944158a9c790b5 873 Pfam PF00688 TGF-beta propeptide 65 159 5.2E-5 T 23-10-2018 IPR001111 TGF-beta, propeptide A0127_03175 57e8c0b6d385e2cd3f45473c5b2f711e 742 Gene3D G3DSA:3.30.450.20 104 195 3.9E-32 T 23-10-2018 A0127_03175 57e8c0b6d385e2cd3f45473c5b2f711e 742 Gene3D G3DSA:1.10.287.950 436 741 6.7E-62 T 23-10-2018 A0127_03175 57e8c0b6d385e2cd3f45473c5b2f711e 742 Gene3D G3DSA:1.20.1480.50 298 398 4.0E-6 T 23-10-2018 A0127_03175 57e8c0b6d385e2cd3f45473c5b2f711e 742 SMART SM00283 466 741 4.2E-52 T 23-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 A0127_03175 57e8c0b6d385e2cd3f45473c5b2f711e 742 SUPERFAMILY SSF103190 104 202 2.43E-9 T 23-10-2018 IPR029151 Periplasmic sensor-like domain superfamily A0127_03175 57e8c0b6d385e2cd3f45473c5b2f711e 742 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 529 672 4.8E-35 T 23-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 A0127_03175 57e8c0b6d385e2cd3f45473c5b2f711e 742 Gene3D G3DSA:3.30.450.20 196 295 3.9E-32 T 23-10-2018 A0127_03175 57e8c0b6d385e2cd3f45473c5b2f711e 742 SUPERFAMILY SSF58104 369 740 5.23E-58 T 23-10-2018 A0127_03175 57e8c0b6d385e2cd3f45473c5b2f711e 742 Pfam PF02743 Cache domain 45 285 2.4E-37 T 23-10-2018 IPR033479 Double Cache domain 1 A0127_01455 3d49e945f70954e0a2b08ffb59f744f3 244 SUPERFAMILY SSF159713 8 242 1.44E-58 T 23-10-2018 A0127_01455 3d49e945f70954e0a2b08ffb59f744f3 244 Pfam PF13938 Putative heavy-metal chelation 14 89 2.0E-10 T 23-10-2018 IPR025251 Domain of unknown function DUF4213 A0127_01455 3d49e945f70954e0a2b08ffb59f744f3 244 Gene3D G3DSA:3.30.390.100 29 217 1.6E-22 T 23-10-2018 A0127_01455 3d49e945f70954e0a2b08ffb59f744f3 244 Gene3D G3DSA:3.40.50.11590 99 215 1.6E-22 T 23-10-2018 A0127_01455 3d49e945f70954e0a2b08ffb59f744f3 244 Pfam PF04016 Putative heavy-metal chelation 107 241 6.6E-36 T 23-10-2018 IPR007161 Putative heavy-metal chelation domain A0127_04755 dabf8270d3d6980d0deaa8b53d90bbae 568 Gene3D G3DSA:2.30.130.10 502 568 7.7E-25 T 23-10-2018 IPR036974 PUA domain superfamily GO:0003723 A0127_04755 dabf8270d3d6980d0deaa8b53d90bbae 568 SUPERFAMILY SSF52141 265 421 1.7E-40 T 23-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 A0127_04755 dabf8270d3d6980d0deaa8b53d90bbae 568 SUPERFAMILY SSF88802 247 499 1.9E-17 T 23-10-2018 A0127_04755 dabf8270d3d6980d0deaa8b53d90bbae 568 SUPERFAMILY SSF88697 511 566 6.84E-13 T 23-10-2018 IPR015947 PUA-like superfamily A0127_04755 dabf8270d3d6980d0deaa8b53d90bbae 568 TIGRFAM TIGR00451 unchar_dom_2: uncharacterized domain 2 511 565 1.8E-9 T 23-10-2018 IPR004521 Uncharacterised domain CHP00451 GO:0003723 A0127_04755 dabf8270d3d6980d0deaa8b53d90bbae 568 Gene3D G3DSA:3.40.50.10630 252 423 1.5E-47 T 23-10-2018 A0127_04755 dabf8270d3d6980d0deaa8b53d90bbae 568 SUPERFAMILY SSF51713 1 243 1.2E-23 T 23-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 A0127_04755 dabf8270d3d6980d0deaa8b53d90bbae 568 SMART SM00359 502 568 4.4E-8 T 23-10-2018 IPR002478 PUA domain GO:0003723 A0127_04755 dabf8270d3d6980d0deaa8b53d90bbae 568 Pfam PF01472 PUA domain 512 566 3.4E-10 T 23-10-2018 IPR002478 PUA domain GO:0003723 A0127_04755 dabf8270d3d6980d0deaa8b53d90bbae 568 Pfam PF14810 Patch-forming domain C2 of tRNA-guanine transglycosylase 438 499 1.8E-6 T 23-10-2018 IPR029402 tRNA-guanine transglycosylase, patch-forming domain C2 MetaCyc: PWY-6711|MetaCyc: PWY-7923 A0127_02880 d191ea2afe8b1a6ce83b505d285b02c1 148 SUPERFAMILY SSF46785 50 126 3.07E-6 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A0127_02880 d191ea2afe8b1a6ce83b505d285b02c1 148 Gene3D G3DSA:1.10.10.10 54 129 1.8E-5 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A0127_06245 268f44e67bdee5fb4cccaaa3da8ca8f3 404 Gene3D G3DSA:1.10.443.10 169 364 1.6E-11 T 23-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 A0127_06245 268f44e67bdee5fb4cccaaa3da8ca8f3 404 Pfam PF00589 Phage integrase family 201 344 2.8E-7 T 23-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 A0127_06245 268f44e67bdee5fb4cccaaa3da8ca8f3 404 SUPERFAMILY SSF56349 197 347 2.85E-13 T 23-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A0127_00385 a6179e1e68f4b19a64d6d1ad6849c4d1 247 SUPERFAMILY SSF52540 1 239 1.67E-38 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_00385 a6179e1e68f4b19a64d6d1ad6849c4d1 247 Gene3D G3DSA:3.40.50.300 1 243 1.0E-56 T 23-10-2018 A0127_00385 a6179e1e68f4b19a64d6d1ad6849c4d1 247 Pfam PF03029 Conserved hypothetical ATP binding protein 6 241 1.2E-51 T 23-10-2018 IPR004130 GPN-loop GTPase A0127_07570 a148dac5dd70f848641aa096af449230 201 Pfam PF17144 Ribosomal large subunit proteins 60S L5, and 50S L18 6 93 3.2E-15 T 23-10-2018 IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0008097 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_07570 a148dac5dd70f848641aa096af449230 201 Pfam PF17144 Ribosomal large subunit proteins 60S L5, and 50S L18 100 134 8.7E-9 T 23-10-2018 IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0008097 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_07570 a148dac5dd70f848641aa096af449230 201 Gene3D G3DSA:3.30.420.100 1 197 1.2E-71 T 23-10-2018 A0127_07570 a148dac5dd70f848641aa096af449230 201 PRINTS PR00058 Ribosomal protein L5 signature 123 142 6.7E-10 T 23-10-2018 IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0008097 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_07570 a148dac5dd70f848641aa096af449230 201 PRINTS PR00058 Ribosomal protein L5 signature 1 12 6.7E-10 T 23-10-2018 IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0008097 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_07570 a148dac5dd70f848641aa096af449230 201 PRINTS PR00058 Ribosomal protein L5 signature 103 122 6.7E-10 T 23-10-2018 IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0008097 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_07570 a148dac5dd70f848641aa096af449230 201 Pfam PF14204 Ribosomal L18 C-terminal region 143 194 1.2E-10 T 23-10-2018 IPR025607 Ribosomal protein L5 eukaryotic/L18 archaeal, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_07570 a148dac5dd70f848641aa096af449230 201 Hamap MF_01337_A 50S ribosomal protein L18 [rplR]. 5 192 45.011 T 23-10-2018 IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0008097 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_07570 a148dac5dd70f848641aa096af449230 201 SUPERFAMILY SSF53137 2 195 4.8E-63 T 23-10-2018 A0127_08345 3d8757123cf501d6917f4ebd0ef0825b 442 Gene3D G3DSA:3.50.50.60 44 242 1.6E-114 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A0127_08345 3d8757123cf501d6917f4ebd0ef0825b 442 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 290 2.2E-57 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A0127_08345 3d8757123cf501d6917f4ebd0ef0825b 442 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 150 175 1.4E-22 T 23-10-2018 A0127_08345 3d8757123cf501d6917f4ebd0ef0825b 442 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 1.4E-22 T 23-10-2018 A0127_08345 3d8757123cf501d6917f4ebd0ef0825b 442 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 234 248 1.4E-22 T 23-10-2018 A0127_08345 3d8757123cf501d6917f4ebd0ef0825b 442 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 275 282 1.4E-22 T 23-10-2018 A0127_08345 3d8757123cf501d6917f4ebd0ef0825b 442 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 385 400 1.4E-22 T 23-10-2018 A0127_08345 3d8757123cf501d6917f4ebd0ef0825b 442 Gene3D G3DSA:3.50.50.60 6 315 1.6E-114 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A0127_08345 3d8757123cf501d6917f4ebd0ef0825b 442 Gene3D G3DSA:3.50.50.60 321 442 3.4E-44 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A0127_08345 3d8757123cf501d6917f4ebd0ef0825b 442 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 327 428 2.1E-18 T 23-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 A0127_08345 3d8757123cf501d6917f4ebd0ef0825b 442 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 260 282 1.8E-27 T 23-10-2018 A0127_08345 3d8757123cf501d6917f4ebd0ef0825b 442 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 233 249 1.8E-27 T 23-10-2018 A0127_08345 3d8757123cf501d6917f4ebd0ef0825b 442 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 1.8E-27 T 23-10-2018 A0127_08345 3d8757123cf501d6917f4ebd0ef0825b 442 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 150 168 1.8E-27 T 23-10-2018 A0127_08345 3d8757123cf501d6917f4ebd0ef0825b 442 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 103 121 1.8E-27 T 23-10-2018 A0127_08345 3d8757123cf501d6917f4ebd0ef0825b 442 SUPERFAMILY SSF51905 1 345 7.05E-49 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A0127_08345 3d8757123cf501d6917f4ebd0ef0825b 442 SUPERFAMILY SSF55424 321 439 1.46E-30 T 23-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 A0127_08345 3d8757123cf501d6917f4ebd0ef0825b 442 TIGRFAM TIGR03385 CoA_CoA_reduc: CoA-disulfide reductase 6 437 4.8E-185 T 23-10-2018 IPR017758 Coenzyme A disulphide reductase GO:0003756|GO:0050451|GO:0050660|GO:0050661|GO:0055114 A0127_03380 681a34f7055a625d5291cd2428281c5a 332 Pfam PF04122 Putative cell wall binding repeat 2 110 188 1.4E-8 T 23-10-2018 IPR007253 Putative cell wall binding repeat 2 A0127_03380 681a34f7055a625d5291cd2428281c5a 332 SUPERFAMILY SSF46785 264 328 2.19E-11 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A0127_03380 681a34f7055a625d5291cd2428281c5a 332 Gene3D G3DSA:1.10.10.10 263 328 3.2E-10 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A0127_03380 681a34f7055a625d5291cd2428281c5a 332 Pfam PF01047 MarR family 275 315 6.1E-6 T 23-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 A0127_04255 f3ccd4a5620cce195b6fb1b724d27912 339 Gene3D G3DSA:3.30.300.110 64 146 2.8E-13 T 23-10-2018 A0127_04255 f3ccd4a5620cce195b6fb1b724d27912 339 Pfam PF02475 Met-10+ like-protein 89 266 1.4E-36 T 23-10-2018 IPR030382 SAM-dependent methyltransferase TRM5/TYW2-type Reactome: R-HSA-6782861 A0127_04255 f3ccd4a5620cce195b6fb1b724d27912 339 SUPERFAMILY SSF53335 88 335 1.63E-46 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A0127_04255 f3ccd4a5620cce195b6fb1b724d27912 339 Gene3D G3DSA:3.40.50.150 150 337 1.1E-34 T 23-10-2018 A0127_02540 df842ccba39f2a3fe6505fd5e02d9726 157 Gene3D G3DSA:3.30.70.640 1 157 7.8E-68 T 23-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A0127_02540 df842ccba39f2a3fe6505fd5e02d9726 157 Pfam PF01967 MoaC family 14 152 5.7E-51 T 23-10-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A0127_02540 df842ccba39f2a3fe6505fd5e02d9726 157 TIGRFAM TIGR00581 moaC: molybdenum cofactor biosynthesis protein C 4 145 1.4E-54 T 23-10-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A0127_02540 df842ccba39f2a3fe6505fd5e02d9726 157 SUPERFAMILY SSF55040 12 153 2.22E-50 T 23-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A0127_02540 df842ccba39f2a3fe6505fd5e02d9726 157 Hamap MF_01224_A Cyclic pyranopterin monophosphate synthase [moaC]. 9 154 39.048 T 23-10-2018 IPR023047 Probable cyclic pyranopterin monophosphate synthase accessory protein, archaea KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823 A0127_02090 07daa1843f2d513b0e83eb17f68fa571 327 SUPERFAMILY SSF64182 18 322 1.57E-49 T 23-10-2018 IPR038763 DHH phosphoesterase superfamily A0127_02090 07daa1843f2d513b0e83eb17f68fa571 327 Pfam PF01368 DHH family 19 158 4.1E-11 T 23-10-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 A0127_02090 07daa1843f2d513b0e83eb17f68fa571 327 Pfam PF02272 DHHA1 domain 207 318 3.2E-13 T 23-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 A0127_02090 07daa1843f2d513b0e83eb17f68fa571 327 Gene3D G3DSA:3.90.1640.10 5 197 2.2E-36 T 23-10-2018 A0127_02090 07daa1843f2d513b0e83eb17f68fa571 327 Gene3D G3DSA:3.10.310.40 219 321 1.0E-7 T 23-10-2018 A0127_01290 83b13b2cc4f245aee7d52083a8c588d6 407 SUPERFAMILY SSF51556 54 344 7.19E-81 T 23-10-2018 IPR032466 Metal-dependent hydrolase A0127_01290 83b13b2cc4f245aee7d52083a8c588d6 407 SUPERFAMILY SSF51338 12 399 4.18E-21 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A0127_01290 83b13b2cc4f245aee7d52083a8c588d6 407 Gene3D G3DSA:2.30.40.10 10 398 2.3E-116 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A0127_01290 83b13b2cc4f245aee7d52083a8c588d6 407 Gene3D G3DSA:3.20.20.140 55 341 2.3E-116 T 23-10-2018 A0127_01290 83b13b2cc4f245aee7d52083a8c588d6 407 Pfam PF01979 Amidohydrolase family 51 395 8.2E-59 T 23-10-2018 IPR006680 Amidohydrolase-related GO:0016787 A0127_03315 26fa99850a1f4f5b4bcb1f0694c7dd46 169 Gene3D G3DSA:3.40.630.30 5 162 2.1E-52 T 23-10-2018 A0127_03315 26fa99850a1f4f5b4bcb1f0694c7dd46 169 Pfam PF00583 Acetyltransferase (GNAT) family 25 144 8.5E-23 T 23-10-2018 IPR000182 GNAT domain A0127_03315 26fa99850a1f4f5b4bcb1f0694c7dd46 169 SUPERFAMILY SSF55729 8 157 2.7E-31 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase A0127_00060 de997cbde5ba11896fdb52ebfd947424 221 Gene3D G3DSA:1.10.10.580 148 217 2.0E-37 T 23-10-2018 IPR023093 ScpA-like, C-terminal A0127_00060 de997cbde5ba11896fdb52ebfd947424 221 Pfam PF02616 Segregation and condensation protein ScpA 18 163 4.2E-11 T 23-10-2018 IPR003768 Segregation and condensation protein A A0127_05770 57c76429ceef5197d6bbe2950b257645 154 Pfam PF00565 Staphylococcal nuclease homologue 57 143 1.0E-9 T 23-10-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold Reactome: R-HSA-6802952 A0127_05770 57c76429ceef5197d6bbe2950b257645 154 SMART SM00318 27 153 1.1E-7 T 23-10-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold Reactome: R-HSA-6802952 A0127_05770 57c76429ceef5197d6bbe2950b257645 154 SUPERFAMILY SSF50199 29 147 1.09E-22 T 23-10-2018 A0127_05770 57c76429ceef5197d6bbe2950b257645 154 Gene3D G3DSA:2.40.50.90 25 150 9.7E-21 T 23-10-2018 IPR035437 SNase-like, OB-fold superfamily A0127_02005 0dafb9b367c8b267139088f6fdd24177 333 TIGRFAM TIGR00303 TIGR00303: TIGR00303 family protein 2 323 4.3E-101 T 23-10-2018 IPR002805 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, putative A0127_02005 0dafb9b367c8b267139088f6fdd24177 333 Hamap MF_01086 UPF0284 protein . 1 333 137.588 T 23-10-2018 IPR002805 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, putative A0127_02005 0dafb9b367c8b267139088f6fdd24177 333 SUPERFAMILY SSF52733 18 326 2.09E-41 T 23-10-2018 IPR036087 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like superfamily GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 A0127_02005 0dafb9b367c8b267139088f6fdd24177 333 Gene3D G3DSA:3.40.50.10210 1 333 1.7E-126 T 23-10-2018 A0127_05155 bb2563b6514b5548cf3e960f66a29163 233 Gene3D G3DSA:3.40.50.300 3 230 6.4E-54 T 23-10-2018 A0127_05155 bb2563b6514b5548cf3e960f66a29163 233 Pfam PF06745 KaiC 9 228 2.6E-50 T 23-10-2018 IPR014774 KaiC-like domain A0127_05155 bb2563b6514b5548cf3e960f66a29163 233 SUPERFAMILY SSF52540 5 230 8.49E-37 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_06820 7b6e8b7b1f03995b71c6a15864cb931d 243 Pfam PF01381 Helix-turn-helix 28 75 7.2E-9 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A0127_06820 7b6e8b7b1f03995b71c6a15864cb931d 243 SMART SM00530 26 81 2.9E-12 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A0127_06820 7b6e8b7b1f03995b71c6a15864cb931d 243 SUPERFAMILY SSF47413 22 75 6.4E-12 T 23-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A0127_06820 7b6e8b7b1f03995b71c6a15864cb931d 243 Gene3D G3DSA:1.10.260.40 24 80 1.1E-10 T 23-10-2018 A0127_06820 7b6e8b7b1f03995b71c6a15864cb931d 243 PIRSF PIRSF037724 1 237 6.1E-105 T 23-10-2018 IPR017271 Transcription regulator HTH, MJ1545, predicted A0127_06820 7b6e8b7b1f03995b71c6a15864cb931d 243 SUPERFAMILY SSF75138 113 223 9.42E-5 T 23-10-2018 IPR028979 HPr(Ser) kinase/phosphorylase-like, N-terminal domain superfamily A0127_04795 05076e8251ade3d9e60c336ca183568a 769 SUPERFAMILY SSF58104 432 768 1.24E-62 T 23-10-2018 A0127_04795 05076e8251ade3d9e60c336ca183568a 769 Pfam PF02743 Cache domain 71 297 1.4E-41 T 23-10-2018 IPR033479 Double Cache domain 1 A0127_04795 05076e8251ade3d9e60c336ca183568a 769 Gene3D G3DSA:1.10.287.950 462 768 4.8E-65 T 23-10-2018 A0127_04795 05076e8251ade3d9e60c336ca183568a 769 SUPERFAMILY SSF103190 122 217 7.26E-15 T 23-10-2018 IPR029151 Periplasmic sensor-like domain superfamily A0127_04795 05076e8251ade3d9e60c336ca183568a 769 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 553 690 5.8E-39 T 23-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 A0127_04795 05076e8251ade3d9e60c336ca183568a 769 SMART SM00283 493 768 3.4E-67 T 23-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 A0127_04795 05076e8251ade3d9e60c336ca183568a 769 Gene3D G3DSA:3.30.450.20 100 206 1.4E-29 T 23-10-2018 A0127_04795 05076e8251ade3d9e60c336ca183568a 769 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 591 618 3.0E-22 T 23-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 A0127_04795 05076e8251ade3d9e60c336ca183568a 769 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 620 649 3.0E-22 T 23-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 A0127_04795 05076e8251ade3d9e60c336ca183568a 769 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 514 543 3.0E-22 T 23-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 A0127_04795 05076e8251ade3d9e60c336ca183568a 769 Pfam PF00672 HAMP domain 363 411 2.2E-6 T 23-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A0127_04795 05076e8251ade3d9e60c336ca183568a 769 SMART SM00304 709 765 51.0 T 23-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A0127_04795 05076e8251ade3d9e60c336ca183568a 769 SMART SM00304 361 419 9.9E-5 T 23-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A0127_04795 05076e8251ade3d9e60c336ca183568a 769 SMART SM00304 457 510 41.0 T 23-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 A0127_04795 05076e8251ade3d9e60c336ca183568a 769 Gene3D G3DSA:1.20.1480.50 321 426 2.9E-7 T 23-10-2018 A0127_04795 05076e8251ade3d9e60c336ca183568a 769 Gene3D G3DSA:3.30.450.20 207 310 3.5E-6 T 23-10-2018 A0127_08495 3c33296927bd87820d9edb76c37e26e2 340 Gene3D G3DSA:1.10.150.20 221 281 3.5E-21 T 23-10-2018 A0127_08495 3c33296927bd87820d9edb76c37e26e2 340 Gene3D G3DSA:3.40.50.1010 1 220 2.3E-89 T 23-10-2018 A0127_08495 3c33296927bd87820d9edb76c37e26e2 340 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 75 94 3.8E-33 T 23-10-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 A0127_08495 3c33296927bd87820d9edb76c37e26e2 340 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 139 156 3.8E-33 T 23-10-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 A0127_08495 3c33296927bd87820d9edb76c37e26e2 340 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 226 241 3.8E-33 T 23-10-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 A0127_08495 3c33296927bd87820d9edb76c37e26e2 340 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 160 180 3.8E-33 T 23-10-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 A0127_08495 3c33296927bd87820d9edb76c37e26e2 340 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 21 35 3.8E-33 T 23-10-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 A0127_08495 3c33296927bd87820d9edb76c37e26e2 340 TIGRFAM TIGR03674 fen_arch: flap structure-specific endonuclease 1 338 2.3E-157 T 23-10-2018 IPR019973 Flap structure-specific endonuclease, archaea GO:0016788 A0127_08495 3c33296927bd87820d9edb76c37e26e2 340 SMART SM00484 140 221 2.6E-36 T 23-10-2018 IPR006086 XPG-I domain GO:0004518 A0127_08495 3c33296927bd87820d9edb76c37e26e2 340 Pfam PF00752 XPG N-terminal domain 12 101 1.5E-22 T 23-10-2018 IPR006085 XPG N-terminal GO:0004518|GO:0006281 A0127_08495 3c33296927bd87820d9edb76c37e26e2 340 ProSitePatterns PS00841 XPG protein signature 1. 73 87 - T 23-10-2018 IPR019974 XPG conserved site GO:0016788 A0127_08495 3c33296927bd87820d9edb76c37e26e2 340 Pfam PF00867 XPG I-region 141 236 5.9E-28 T 23-10-2018 IPR006086 XPG-I domain GO:0004518 A0127_08495 3c33296927bd87820d9edb76c37e26e2 340 SUPERFAMILY SSF47807 221 339 1.23E-33 T 23-10-2018 IPR036279 5'-3' exonuclease, C-terminal domain superfamily A0127_08495 3c33296927bd87820d9edb76c37e26e2 340 SMART SM00279 223 257 1.6E-11 T 23-10-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 A0127_08495 3c33296927bd87820d9edb76c37e26e2 340 Hamap MF_00614 Flap endonuclease 1 [fen]. 1 339 148.824 T 23-10-2018 IPR023426 Flap endonuclease 1 GO:0016788 Reactome: R-HSA-110362|Reactome: R-HSA-162594|Reactome: R-HSA-174437|Reactome: R-HSA-5651801|Reactome: R-HSA-5685939|Reactome: R-HSA-69166 A0127_08495 3c33296927bd87820d9edb76c37e26e2 340 SMART SM00485 1 101 5.5E-52 T 23-10-2018 IPR006085 XPG N-terminal GO:0004518|GO:0006281 A0127_08495 3c33296927bd87820d9edb76c37e26e2 340 SUPERFAMILY SSF88723 7 236 3.92E-67 T 23-10-2018 IPR029060 PIN-like domain superfamily A0127_08865 46a002df5dd1b9463e1400ef291024ad 433 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 23 430 5.3E-98 T 23-10-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 A0127_08865 46a002df5dd1b9463e1400ef291024ad 433 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 348 368 - T 23-10-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 A0127_08865 46a002df5dd1b9463e1400ef291024ad 433 Pfam PF00860 Permease family 24 401 3.6E-96 T 23-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 A0127_00365 5eed73bb5b3425f1b02f1644cea0d308 188 TIGRFAM TIGR00172 maf: septum formation protein Maf 2 177 2.9E-49 T 23-10-2018 IPR003697 Maf-like protein GO:0047429 A0127_00365 5eed73bb5b3425f1b02f1644cea0d308 188 Gene3D G3DSA:3.90.950.10 1 182 1.2E-64 T 23-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like A0127_00365 5eed73bb5b3425f1b02f1644cea0d308 188 SUPERFAMILY SSF52972 2 177 6.54E-57 T 23-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like A0127_00365 5eed73bb5b3425f1b02f1644cea0d308 188 PIRSF PIRSF006305 1 186 9.4E-59 T 23-10-2018 IPR003697 Maf-like protein GO:0047429 A0127_00365 5eed73bb5b3425f1b02f1644cea0d308 188 Pfam PF02545 Maf-like protein 2 176 3.3E-55 T 23-10-2018 IPR003697 Maf-like protein GO:0047429 A0127_00365 5eed73bb5b3425f1b02f1644cea0d308 188 Hamap MF_00528 Septum formation protein Maf [maf]. 1 185 30.406 T 23-10-2018 IPR003697 Maf-like protein GO:0047429 A0127_03705 f0c02b000823368433b21637bdc03c55 109 SUPERFAMILY SSF46785 18 107 2.18E-9 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A0127_03705 f0c02b000823368433b21637bdc03c55 109 Pfam PF07381 Winged helix DNA-binding domain (DUF1495) 10 98 1.6E-34 T 23-10-2018 IPR010863 Protein of unknown function DUF1495 A0127_00970 2475909d0a03d4d70a111eab14a2519b 361 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 3 22 4.5E-23 T 23-10-2018 A0127_00970 2475909d0a03d4d70a111eab14a2519b 361 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 215 231 4.5E-23 T 23-10-2018 A0127_00970 2475909d0a03d4d70a111eab14a2519b 361 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 137 155 4.5E-23 T 23-10-2018 A0127_00970 2475909d0a03d4d70a111eab14a2519b 361 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 94 112 4.5E-23 T 23-10-2018 A0127_00970 2475909d0a03d4d70a111eab14a2519b 361 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 240 262 4.5E-23 T 23-10-2018 A0127_00970 2475909d0a03d4d70a111eab14a2519b 361 Gene3D G3DSA:3.30.390.30 299 359 6.3E-25 T 23-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 A0127_00970 2475909d0a03d4d70a111eab14a2519b 361 SUPERFAMILY SSF55424 290 351 3.02E-26 T 23-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 A0127_00970 2475909d0a03d4d70a111eab14a2519b 361 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 133 157 8.5E-8 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A0127_00970 2475909d0a03d4d70a111eab14a2519b 361 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 250 268 8.5E-8 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A0127_00970 2475909d0a03d4d70a111eab14a2519b 361 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 2 24 8.5E-8 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A0127_00970 2475909d0a03d4d70a111eab14a2519b 361 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 95 103 8.5E-8 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A0127_00970 2475909d0a03d4d70a111eab14a2519b 361 Gene3D G3DSA:3.50.50.60 106 223 1.1E-100 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A0127_00970 2475909d0a03d4d70a111eab14a2519b 361 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 263 5.9E-55 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A0127_00970 2475909d0a03d4d70a111eab14a2519b 361 Gene3D G3DSA:3.50.50.60 3 275 1.1E-100 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A0127_00970 2475909d0a03d4d70a111eab14a2519b 361 SUPERFAMILY SSF51905 1 289 3.4E-41 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A0127_01045 5b5fb02db6dbc4d08fa6444b3084975c 602 Gene3D G3DSA:3.40.50.10490 251 601 2.8E-139 T 23-10-2018 A0127_01045 5b5fb02db6dbc4d08fa6444b3084975c 602 SUPERFAMILY SSF56235 2 229 9.44E-75 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A0127_01045 5b5fb02db6dbc4d08fa6444b3084975c 602 Pfam PF01380 SIS domain 457 584 3.4E-24 T 23-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 A0127_01045 5b5fb02db6dbc4d08fa6444b3084975c 602 Pfam PF01380 SIS domain 284 412 1.2E-33 T 23-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 A0127_01045 5b5fb02db6dbc4d08fa6444b3084975c 602 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 602 2.8E-249 T 23-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 A0127_01045 5b5fb02db6dbc4d08fa6444b3084975c 602 Gene3D G3DSA:3.60.20.10 2 240 3.5E-79 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A0127_01045 5b5fb02db6dbc4d08fa6444b3084975c 602 Gene3D G3DSA:3.40.50.10490 442 587 2.8E-139 T 23-10-2018 A0127_01045 5b5fb02db6dbc4d08fa6444b3084975c 602 Pfam PF13522 Glutamine amidotransferase domain 65 193 3.3E-24 T 23-10-2018 A0127_01045 5b5fb02db6dbc4d08fa6444b3084975c 602 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 602 41.193 T 23-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 A0127_01045 5b5fb02db6dbc4d08fa6444b3084975c 602 SUPERFAMILY SSF53697 247 602 3.43E-111 T 23-10-2018 A0127_08340 891d92a7211127caad7dec9cf9fbcae8 391 Pfam PF04981 NMD3 family 6 276 1.9E-65 T 23-10-2018 IPR007064 Nmd3, N-terminal A0127_08340 891d92a7211127caad7dec9cf9fbcae8 391 SUPERFAMILY SSF50249 332 382 7.28E-6 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A0127_08340 891d92a7211127caad7dec9cf9fbcae8 391 Gene3D G3DSA:2.40.50.140 332 385 2.8E-8 T 23-10-2018 A0127_06140 90fb174207248d3834d85f79f6f3a4c7 840 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 134 626 2.7E-21 T 23-10-2018 IPR000914 Solute-binding protein family 5 domain A0127_06140 90fb174207248d3834d85f79f6f3a4c7 840 Gene3D G3DSA:3.40.190.10 317 424 1.4E-16 T 23-10-2018 A0127_06140 90fb174207248d3834d85f79f6f3a4c7 840 Gene3D G3DSA:3.10.105.10 425 625 1.4E-16 T 23-10-2018 A0127_06140 90fb174207248d3834d85f79f6f3a4c7 840 SUPERFAMILY SSF53850 135 647 1.47E-20 T 23-10-2018 A0127_06140 90fb174207248d3834d85f79f6f3a4c7 840 TIGRFAM TIGR04288 CGP_CTERM: CGP-CTERM domain 820 839 4.4E-8 T 23-10-2018 IPR027552 CGP-CTERM domain A0127_05105 c5d91538532578b0ff0145658b228149 104 Pfam PF03091 CutA1 divalent ion tolerance protein 4 99 1.6E-30 T 23-10-2018 IPR004323 Divalent ion tolerance protein, CutA GO:0010038 A0127_05105 c5d91538532578b0ff0145658b228149 104 Gene3D G3DSA:3.30.70.120 1 103 1.3E-35 T 23-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal A0127_05105 c5d91538532578b0ff0145658b228149 104 SUPERFAMILY SSF54913 3 100 4.45E-32 T 23-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta A0127_03955 a3156d5c6c787f2311ce9ec59ab217c7 167 ProSitePatterns PS00893 Nudix box signature. 73 94 - T 23-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 A0127_03955 a3156d5c6c787f2311ce9ec59ab217c7 167 Gene3D G3DSA:3.90.79.10 38 166 1.4E-42 T 23-10-2018 A0127_03955 a3156d5c6c787f2311ce9ec59ab217c7 167 SUPERFAMILY SSF55811 40 165 1.62E-35 T 23-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 A0127_03955 a3156d5c6c787f2311ce9ec59ab217c7 167 Pfam PF00293 NUDIX domain 44 162 2.6E-23 T 23-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 A0127_03955 a3156d5c6c787f2311ce9ec59ab217c7 167 PRINTS PR00502 NUDIX hydrolase family signature 68 82 1.7E-8 T 23-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 A0127_03955 a3156d5c6c787f2311ce9ec59ab217c7 167 PRINTS PR00502 NUDIX hydrolase family signature 82 97 1.7E-8 T 23-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 A0127_09130 6c4d212902fe229c219c7163b18d4781 272 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 13 266 5.0E-71 T 23-10-2018 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 A0127_09130 6c4d212902fe229c219c7163b18d4781 272 Gene3D G3DSA:3.20.20.20 1 270 1.0E-89 T 23-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A0127_09130 6c4d212902fe229c219c7163b18d4781 272 Pfam PF00809 Pterin binding enzyme 14 252 1.9E-60 T 23-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A0127_09130 6c4d212902fe229c219c7163b18d4781 272 SUPERFAMILY SSF51717 8 268 1.7E-80 T 23-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A0127_00625 fbdddd0c4703f7f5310e07afd724bb77 349 Pfam PF04055 Radical SAM superfamily 78 234 2.3E-22 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A0127_00625 fbdddd0c4703f7f5310e07afd724bb77 349 Gene3D G3DSA:3.20.20.70 62 286 4.0E-37 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A0127_00625 fbdddd0c4703f7f5310e07afd724bb77 349 SUPERFAMILY SSF102114 57 317 1.83E-36 T 23-10-2018 A0127_00625 fbdddd0c4703f7f5310e07afd724bb77 349 TIGRFAM TIGR04337 AmmeMemoSam_rS: AmmeMemoRadiSam system radical SAM enzyme 5 342 1.4E-112 T 23-10-2018 IPR027596 AmmeMemoRadiSam system radical SAM enzyme A0127_00625 fbdddd0c4703f7f5310e07afd724bb77 349 Pfam PF13353 4Fe-4S single cluster domain 73 166 2.3E-7 T 23-10-2018 A0127_00625 fbdddd0c4703f7f5310e07afd724bb77 349 PIRSF PIRSF004869 1 313 3.7E-99 T 23-10-2018 IPR016431 Pyruvate-formate lyase-activating enzyme, predicted A0127_07050 fc458bd33e3766d7a7a4bf902b58243f 137 Gene3D G3DSA:3.30.110.150 53 137 1.9E-24 T 23-10-2018 IPR038594 SepF-like superfamily A0127_07050 fc458bd33e3766d7a7a4bf902b58243f 137 PIRSF PIRSF019313 1 137 8.1E-27 T 23-10-2018 IPR012426 Uncharacterised protein family SepF-related, archaea A0127_07050 fc458bd33e3766d7a7a4bf902b58243f 137 Pfam PF04472 Cell division protein SepF 63 135 4.2E-16 T 23-10-2018 IPR007561 Cell division protein SepF/SepF-related GO:0090529 A0127_05515 e6921027e27fab0337ddb0275773d73e 530 Gene3D G3DSA:2.60.40.10 105 213 1.9E-8 T 23-10-2018 IPR013783 Immunoglobulin-like fold A0127_05515 e6921027e27fab0337ddb0275773d73e 530 Pfam PF07705 CARDB 111 193 4.1E-6 T 23-10-2018 IPR011635 CARDB domain A0127_08985 ef04a9708c1d3f8fc855b3be6abbdcdf 358 SUPERFAMILY SSF52540 168 350 2.1E-43 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_08985 ef04a9708c1d3f8fc855b3be6abbdcdf 358 Gene3D G3DSA:3.40.50.300 162 357 1.0E-58 T 23-10-2018 A0127_08985 ef04a9708c1d3f8fc855b3be6abbdcdf 358 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 169 328 1.6E-17 T 23-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 A0127_08985 ef04a9708c1d3f8fc855b3be6abbdcdf 358 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 218 233 1.2E-13 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A0127_08985 ef04a9708c1d3f8fc855b3be6abbdcdf 358 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 170 190 1.2E-13 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A0127_08985 ef04a9708c1d3f8fc855b3be6abbdcdf 358 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 191 209 1.2E-13 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A0127_08985 ef04a9708c1d3f8fc855b3be6abbdcdf 358 Gene3D G3DSA:1.20.120.1190 1 161 2.4E-55 T 23-10-2018 A0127_08985 ef04a9708c1d3f8fc855b3be6abbdcdf 358 Pfam PF06858 Nucleolar GTP-binding protein 1 (NOG1) 234 291 4.8E-24 T 23-10-2018 IPR010674 Nucleolar GTP-binding protein 1, Rossman-fold domain GO:0005525 A0127_09105 0dd2ebd1aa7c0d6f97b3edc45da3728f 130 Gene3D G3DSA:1.10.1520.20 2 129 2.1E-46 T 23-10-2018 IPR038133 Ribonuclease III superfamily, archaeal A0127_09105 0dd2ebd1aa7c0d6f97b3edc45da3728f 130 Pfam PF11469 Ribonuclease III 10 127 1.3E-62 T 23-10-2018 IPR021568 Ribonuclease III, archaeal A0127_09105 0dd2ebd1aa7c0d6f97b3edc45da3728f 130 SUPERFAMILY SSF69065 7 129 1.59E-57 T 23-10-2018 IPR036389 Ribonuclease III, endonuclease domain superfamily GO:0004525|GO:0006396 A0127_01605 24c35fa593dfc1023465f03d1bf26fed 235 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 1 196 1.3E-29 T 23-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 A0127_01605 24c35fa593dfc1023465f03d1bf26fed 235 TIGRFAM TIGR00040 yfcE: phosphodiesterase, MJ0936 family 1 197 4.5E-17 T 23-10-2018 IPR000979 Phosphodiesterase MJ0936/Vps29 Reactome: R-HSA-3238698 A0127_01605 24c35fa593dfc1023465f03d1bf26fed 235 Gene3D G3DSA:3.60.21.10 2 235 1.2E-70 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like A0127_01605 24c35fa593dfc1023465f03d1bf26fed 235 PIRSF PIRSF000883 1 235 3.1E-72 T 23-10-2018 IPR011152 Phosphoesterase MJ0912 A0127_01605 24c35fa593dfc1023465f03d1bf26fed 235 SUPERFAMILY SSF56300 1 234 1.31E-65 T 23-10-2018 A0127_05980 81ae809f4d369b00787ae4b28104cdd1 499 Gene3D G3DSA:1.10.1370.30 1 499 6.9E-199 T 23-10-2018 A0127_05980 81ae809f4d369b00787ae4b28104cdd1 499 SUPERFAMILY SSF55486 7 499 3.05E-116 T 23-10-2018 A0127_05980 81ae809f4d369b00787ae4b28104cdd1 499 PIRSF PIRSF006615 5 499 1.7E-198 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A0127_05980 81ae809f4d369b00787ae4b28104cdd1 499 Pfam PF02074 Carboxypeptidase Taq (M32) metallopeptidase 12 498 3.8E-108 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A0127_05980 81ae809f4d369b00787ae4b28104cdd1 499 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 296 312 3.9E-87 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A0127_05980 81ae809f4d369b00787ae4b28104cdd1 499 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 269 288 3.9E-87 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A0127_05980 81ae809f4d369b00787ae4b28104cdd1 499 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 336 355 3.9E-87 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A0127_05980 81ae809f4d369b00787ae4b28104cdd1 499 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 405 426 3.9E-87 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A0127_05980 81ae809f4d369b00787ae4b28104cdd1 499 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 249 268 3.9E-87 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A0127_05980 81ae809f4d369b00787ae4b28104cdd1 499 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 232 248 3.9E-87 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A0127_05980 81ae809f4d369b00787ae4b28104cdd1 499 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 382 399 3.9E-87 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A0127_05980 81ae809f4d369b00787ae4b28104cdd1 499 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 450 468 3.9E-87 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A0127_05980 81ae809f4d369b00787ae4b28104cdd1 499 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 150 170 3.9E-87 T 23-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 A0127_04655 ec59818da39ba0674a791ed25a5de850 56 Hamap MF_00751 Preprotein translocase subunit SecG [secG]. 1 51 14.823 T 23-10-2018 IPR023531 Preprotein translocase subunit SecG A0127_04655 ec59818da39ba0674a791ed25a5de850 56 Pfam PF03911 Sec61beta family 11 51 7.7E-16 T 23-10-2018 IPR016482 Protein transport protein SecG/Sec61-beta/Sbh Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A0127_07550 ecd4499b28abc536b8d7326ba191ada1 130 ProSitePatterns PS00053 Ribosomal protein S8 signature. 100 117 - T 23-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_07550 ecd4499b28abc536b8d7326ba191ada1 130 Gene3D G3DSA:3.30.1490.10 70 128 3.9E-28 T 23-10-2018 A0127_07550 ecd4499b28abc536b8d7326ba191ada1 130 Pfam PF00410 Ribosomal protein S8 5 130 9.9E-28 T 23-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_07550 ecd4499b28abc536b8d7326ba191ada1 130 Gene3D G3DSA:3.30.1370.30 1 69 2.8E-31 T 23-10-2018 A0127_07550 ecd4499b28abc536b8d7326ba191ada1 130 Hamap MF_01302_A 30S ribosomal protein S8 [rpsH]. 2 130 38.053 T 23-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_07550 ecd4499b28abc536b8d7326ba191ada1 130 SUPERFAMILY SSF56047 3 130 6.67E-40 T 23-10-2018 IPR035987 Ribosomal protein S8 superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_08165 b0d68a24121f40beea35136e59ea7575 495 Gene3D G3DSA:1.10.10.1100 392 472 3.2E-18 T 23-10-2018 A0127_08165 b0d68a24121f40beea35136e59ea7575 495 Pfam PF01266 FAD dependent oxidoreductase 4 356 1.1E-68 T 23-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 A0127_08165 b0d68a24121f40beea35136e59ea7575 495 Gene3D G3DSA:3.50.50.60 5 353 1.3E-114 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A0127_08165 b0d68a24121f40beea35136e59ea7575 495 SUPERFAMILY SSF51905 3 389 1.51E-56 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A0127_08165 b0d68a24121f40beea35136e59ea7575 495 SUPERFAMILY SSF54373 223 318 5.76E-8 T 23-10-2018 A0127_08165 b0d68a24121f40beea35136e59ea7575 495 Pfam PF04324 BFD-like [2Fe-2S] binding domain 405 463 4.5E-16 T 23-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain A0127_08165 b0d68a24121f40beea35136e59ea7575 495 Gene3D G3DSA:3.30.9.10 90 321 1.3E-114 T 23-10-2018 A0127_07095 789cd494cb445c2d7733a364a93d6127 522 SUPERFAMILY SSF52096 3 257 7.7E-79 T 23-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A0127_07095 789cd494cb445c2d7733a364a93d6127 522 Gene3D G3DSA:3.90.226.10 1 260 3.3E-99 T 23-10-2018 A0127_07095 789cd494cb445c2d7733a364a93d6127 522 SUPERFAMILY SSF52096 244 522 4.76E-93 T 23-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A0127_07095 789cd494cb445c2d7733a364a93d6127 522 Gene3D G3DSA:3.90.226.10 262 522 4.6E-96 T 23-10-2018 A0127_07095 789cd494cb445c2d7733a364a93d6127 522 Pfam PF01039 Carboxyl transferase domain 28 520 8.3E-202 T 23-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 A0127_06350 aff19127636fa4ff878986f6cdc3de2e 300 Gene3D G3DSA:1.10.3720.10 56 297 2.9E-59 T 23-10-2018 IPR035906 MetI-like superfamily A0127_06350 aff19127636fa4ff878986f6cdc3de2e 300 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 91 286 2.9E-16 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A0127_06350 aff19127636fa4ff878986f6cdc3de2e 300 SUPERFAMILY SSF161098 60 285 5.23E-51 T 23-10-2018 IPR035906 MetI-like superfamily A0127_06350 aff19127636fa4ff878986f6cdc3de2e 300 SUPERFAMILY SSF160964 8 56 6.28E-8 T 23-10-2018 A0127_01070 c4778258f70fa22a6b08ccd0427dee81 273 SUPERFAMILY SSF81345 3 272 1.96E-18 T 23-10-2018 IPR037294 ABC transporter, BtuC-like A0127_01070 c4778258f70fa22a6b08ccd0427dee81 273 Pfam PF00950 ABC 3 transport family 4 266 6.8E-27 T 23-10-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 A0127_07545 c26b82cd5ff68c8eebc3f9287e606655 56 ProSitePatterns PS00527 Ribosomal protein S14 signature. 23 44 - T 23-10-2018 IPR018271 Ribosomal protein S14, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_07545 c26b82cd5ff68c8eebc3f9287e606655 56 Pfam PF00253 Ribosomal protein S14p/S29e 8 55 2.4E-9 T 23-10-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 A0127_07545 c26b82cd5ff68c8eebc3f9287e606655 56 Hamap MF_01364_A 30S ribosomal protein S14 type Z [rpsZ]. 2 56 17.471 T 23-10-2018 IPR023676 Ribosomal protein S14, type Z, archaeal GO:0003723|GO:0003735|GO:0006412|GO:0015935 A0127_07545 c26b82cd5ff68c8eebc3f9287e606655 56 Gene3D G3DSA:4.10.830.10 1 56 1.9E-20 T 23-10-2018 A0127_03305 f925636bc19ce5027137679ffd9aadf0 412 Gene3D G3DSA:1.20.1250.20 22 207 5.0E-30 T 23-10-2018 A0127_03305 f925636bc19ce5027137679ffd9aadf0 412 SUPERFAMILY SSF103473 25 411 1.09E-56 T 23-10-2018 IPR036259 MFS transporter superfamily A0127_03305 f925636bc19ce5027137679ffd9aadf0 412 Gene3D G3DSA:1.20.1250.20 241 412 1.5E-24 T 23-10-2018 A0127_03305 f925636bc19ce5027137679ffd9aadf0 412 Pfam PF07690 Major Facilitator Superfamily 33 270 3.9E-24 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A0127_00320 9b0a1b0072f6fb3a9b54d947e7dfb02c 86 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 12 81 7.5E-10 T 23-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family A0127_00320 9b0a1b0072f6fb3a9b54d947e7dfb02c 86 Gene3D G3DSA:3.30.2310.20 1 84 1.1E-21 T 23-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily A0127_00320 9b0a1b0072f6fb3a9b54d947e7dfb02c 86 SUPERFAMILY SSF143011 1 81 6.15E-24 T 23-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily A0127_03500 cfb1cedfa3d92d47e43f241bcf2f7392 722 SMART SM00487 20 204 5.6E-30 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A0127_03500 cfb1cedfa3d92d47e43f241bcf2f7392 722 Pfam PF14520 Helix-hairpin-helix domain 646 695 9.6E-11 T 23-10-2018 A0127_03500 cfb1cedfa3d92d47e43f241bcf2f7392 722 SUPERFAMILY SSF46785 405 492 1.17E-15 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A0127_03500 cfb1cedfa3d92d47e43f241bcf2f7392 722 Pfam PF00270 DEAD/DEAH box helicase 26 180 3.9E-25 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A0127_03500 cfb1cedfa3d92d47e43f241bcf2f7392 722 Hamap MF_00442 ATP-dependent DNA helicase Hel308 [hel308]. 9 700 30.549 T 23-10-2018 IPR022965 ATP-dependent DNA helicase Hel308 GO:0004386 A0127_03500 cfb1cedfa3d92d47e43f241bcf2f7392 722 SUPERFAMILY SSF52540 196 394 2.86E-41 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_03500 cfb1cedfa3d92d47e43f241bcf2f7392 722 SMART SM00278 678 697 23.0 T 23-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A0127_03500 cfb1cedfa3d92d47e43f241bcf2f7392 722 SMART SM00278 645 664 3.0 T 23-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 A0127_03500 cfb1cedfa3d92d47e43f241bcf2f7392 722 Gene3D G3DSA:1.10.150.20 643 699 3.3E-23 T 23-10-2018 A0127_03500 cfb1cedfa3d92d47e43f241bcf2f7392 722 SUPERFAMILY SSF52540 2 191 1.73E-46 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_03500 cfb1cedfa3d92d47e43f241bcf2f7392 722 Pfam PF00271 Helicase conserved C-terminal domain 233 373 3.4E-9 T 23-10-2018 IPR001650 Helicase, C-terminal A0127_03500 cfb1cedfa3d92d47e43f241bcf2f7392 722 Gene3D G3DSA:1.10.3380.30 411 641 2.8E-73 T 23-10-2018 A0127_03500 cfb1cedfa3d92d47e43f241bcf2f7392 722 Gene3D G3DSA:3.40.50.300 201 399 2.2E-62 T 23-10-2018 A0127_03500 cfb1cedfa3d92d47e43f241bcf2f7392 722 Gene3D G3DSA:3.40.50.300 8 200 2.6E-73 T 23-10-2018 A0127_03500 cfb1cedfa3d92d47e43f241bcf2f7392 722 SMART SM00490 288 374 4.1E-15 T 23-10-2018 IPR001650 Helicase, C-terminal A0127_03500 cfb1cedfa3d92d47e43f241bcf2f7392 722 SUPERFAMILY SSF158702 493 701 2.17E-59 T 23-10-2018 A0127_06400 5700c7de0e2561c1398a4ecf5ed69785 275 SUPERFAMILY SSF103481 39 134 1.44E-13 T 23-10-2018 A0127_06400 5700c7de0e2561c1398a4ecf5ed69785 275 SUPERFAMILY SSF103481 176 269 1.31E-14 T 23-10-2018 A0127_06400 5700c7de0e2561c1398a4ecf5ed69785 275 Pfam PF00892 EamA-like transporter family 139 269 1.6E-18 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A0127_06400 5700c7de0e2561c1398a4ecf5ed69785 275 Pfam PF00892 EamA-like transporter family 3 131 1.2E-23 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A0127_06765 f67f0a064ea541a4ce1035a910f65d21 98 Gene3D G3DSA:3.30.70.330 1 98 4.6E-38 T 23-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily A0127_06765 f67f0a064ea541a4ce1035a910f65d21 98 Hamap MF_00545 30S ribosomal protein S24e [rps24e]. 1 98 20.824 T 23-10-2018 IPR001976 Ribosomal protein S24e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_06765 f67f0a064ea541a4ce1035a910f65d21 98 ProSitePatterns PS00529 Ribosomal protein S24e signature. 60 82 - T 23-10-2018 IPR018098 Ribosomal S24e conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_06765 f67f0a064ea541a4ce1035a910f65d21 98 Pfam PF01282 Ribosomal protein S24e 21 97 1.6E-25 T 23-10-2018 IPR001976 Ribosomal protein S24e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_06765 f67f0a064ea541a4ce1035a910f65d21 98 SUPERFAMILY SSF54189 1 97 1.65E-31 T 23-10-2018 IPR012678 Ribosomal protein L23/L15e core domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 A0127_06765 f67f0a064ea541a4ce1035a910f65d21 98 ProDom PD006052 RIBOSOMAL S24 40S RIBONUCLEOPROTEIN S24E 30S S24 CDNA RIKEN ACETYLATION 11 76 8.0E-33 T 23-10-2018 IPR001976 Ribosomal protein S24e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_01500 2b539c187dec053eb2e3a2116f5d6491 426 ProSitePatterns PS00217 Sugar transport proteins signature 2. 114 139 - T 23-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 A0127_01500 2b539c187dec053eb2e3a2116f5d6491 426 Gene3D G3DSA:1.20.1250.20 6 426 7.3E-79 T 23-10-2018 A0127_01500 2b539c187dec053eb2e3a2116f5d6491 426 SUPERFAMILY SSF103473 6 424 3.53E-77 T 23-10-2018 IPR036259 MFS transporter superfamily A0127_01500 2b539c187dec053eb2e3a2116f5d6491 426 Pfam PF00083 Sugar (and other) transporter 51 425 1.0E-39 T 23-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 A0127_01065 26160ef744dc75f844074dc4e5aa208e 228 Gene3D G3DSA:3.30.420.10 2 161 5.9E-62 T 23-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 A0127_01065 26160ef744dc75f844074dc4e5aa208e 228 TIGRFAM TIGR00729 TIGR00729: ribonuclease HII 4 205 1.7E-73 T 23-10-2018 IPR004649 Ribonuclease H2, subunit A GO:0004523|GO:0016070 A0127_01065 26160ef744dc75f844074dc4e5aa208e 228 Pfam PF01351 Ribonuclease HII 4 200 1.5E-50 T 23-10-2018 IPR024567 Ribonuclease HII/HIII domain A0127_01065 26160ef744dc75f844074dc4e5aa208e 228 Gene3D G3DSA:1.10.10.460 162 208 1.1E-25 T 23-10-2018 IPR023160 Ribonuclease HII, helix-loop-helix cap domain superfamily GO:0004523 A0127_01065 26160ef744dc75f844074dc4e5aa208e 228 SUPERFAMILY SSF53098 2 208 1.97E-59 T 23-10-2018 IPR012337 Ribonuclease H-like superfamily A0127_01065 26160ef744dc75f844074dc4e5aa208e 228 Hamap MF_00052_A Ribonuclease HII [rnhB]. 2 206 37.956 T 23-10-2018 IPR020787 Ribonuclease HII, archaea GO:0004523|GO:0005737|GO:0006401|GO:0030145 A0127_00170 1622bd64a1757a7590a302b90bb876a7 599 SUPERFAMILY SSF51569 1 301 9.16E-87 T 23-10-2018 A0127_00170 1622bd64a1757a7590a302b90bb876a7 599 Pfam PF00682 HMGL-like 3 233 1.1E-41 T 23-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 A0127_00170 1622bd64a1757a7590a302b90bb876a7 599 SUPERFAMILY SSF89000 297 447 4.71E-56 T 23-10-2018 A0127_00170 1622bd64a1757a7590a302b90bb876a7 599 Pfam PF00364 Biotin-requiring enzyme 533 598 2.1E-24 T 23-10-2018 IPR000089 Biotin/lipoyl attachment A0127_00170 1622bd64a1757a7590a302b90bb876a7 599 Gene3D G3DSA:2.40.50.100 526 599 8.4E-29 T 23-10-2018 A0127_00170 1622bd64a1757a7590a302b90bb876a7 599 TIGRFAM TIGR01108 oadA: oxaloacetate decarboxylase alpha subunit 6 594 1.2E-229 T 23-10-2018 IPR005776 Oxaloacetate decarboxylase, alpha subunit GO:0006814|GO:0008948 A0127_00170 1622bd64a1757a7590a302b90bb876a7 599 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 555 572 - T 23-10-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 A0127_00170 1622bd64a1757a7590a302b90bb876a7 599 Gene3D G3DSA:3.20.20.70 1 458 1.1E-168 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A0127_00170 1622bd64a1757a7590a302b90bb876a7 599 SUPERFAMILY SSF51230 525 597 2.09E-25 T 23-10-2018 IPR011053 Single hybrid motif A0127_00170 1622bd64a1757a7590a302b90bb876a7 599 Pfam PF02436 Conserved carboxylase domain 292 474 1.8E-59 T 23-10-2018 IPR003379 Carboxylase, conserved domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 A0127_05330 e8f6e5e09171217ad5267f564b8a540c 513 Pfam PF00361 Proton-conducting membrane transporter 136 436 1.6E-63 T 23-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A0127_05330 e8f6e5e09171217ad5267f564b8a540c 513 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 224 245 4.9E-16 T 23-10-2018 A0127_05330 e8f6e5e09171217ad5267f564b8a540c 513 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 84 109 4.9E-16 T 23-10-2018 A0127_05330 e8f6e5e09171217ad5267f564b8a540c 513 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 112 132 4.9E-16 T 23-10-2018 A0127_05330 e8f6e5e09171217ad5267f564b8a540c 513 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 319 331 4.9E-16 T 23-10-2018 A0127_05330 e8f6e5e09171217ad5267f564b8a540c 513 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 74 122 1.2E-13 T 23-10-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A0127_05390 f3368f31b821680f98f25dd135234644 330 Gene3D G3DSA:3.50.50.60 18 315 7.8E-115 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A0127_05390 f3368f31b821680f98f25dd135234644 330 SUPERFAMILY SSF51905 15 321 4.16E-61 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A0127_05390 f3368f31b821680f98f25dd135234644 330 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 20 39 1.0E-40 T 23-10-2018 A0127_05390 f3368f31b821680f98f25dd135234644 330 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 124 142 1.0E-40 T 23-10-2018 A0127_05390 f3368f31b821680f98f25dd135234644 330 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 249 265 1.0E-40 T 23-10-2018 A0127_05390 f3368f31b821680f98f25dd135234644 330 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 166 184 1.0E-40 T 23-10-2018 A0127_05390 f3368f31b821680f98f25dd135234644 330 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 275 297 1.0E-40 T 23-10-2018 A0127_05390 f3368f31b821680f98f25dd135234644 330 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 154 174 - T 23-10-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 A0127_05390 f3368f31b821680f98f25dd135234644 330 Gene3D G3DSA:3.50.50.60 136 257 7.8E-115 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A0127_05390 f3368f31b821680f98f25dd135234644 330 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 18 321 2.1E-120 T 23-10-2018 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00450+1.8.1.9 A0127_05390 f3368f31b821680f98f25dd135234644 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 147 159 2.5E-65 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A0127_05390 f3368f31b821680f98f25dd135234644 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 125 133 2.5E-65 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A0127_05390 f3368f31b821680f98f25dd135234644 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 285 303 2.5E-65 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A0127_05390 f3368f31b821680f98f25dd135234644 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 19 41 2.5E-65 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A0127_05390 f3368f31b821680f98f25dd135234644 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 51 66 2.5E-65 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A0127_05390 f3368f31b821680f98f25dd135234644 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 213 229 2.5E-65 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A0127_05390 f3368f31b821680f98f25dd135234644 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 72 82 2.5E-65 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A0127_05390 f3368f31b821680f98f25dd135234644 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 162 186 2.5E-65 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A0127_05390 f3368f31b821680f98f25dd135234644 330 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 251 272 2.5E-65 T 23-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 A0127_05390 f3368f31b821680f98f25dd135234644 330 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 19 310 1.5E-60 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A0127_04650 45f6b65a81220d6a3c9c1057c647767d 125 ProSitePatterns PS00578 Ribosomal protein S6e signature. 63 74 - T 23-10-2018 IPR018282 Ribosomal protein S6e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-166208|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_04650 45f6b65a81220d6a3c9c1057c647767d 125 Pfam PF01092 Ribosomal protein S6e 4 124 1.1E-36 T 23-10-2018 IPR001377 Ribosomal protein S6e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-166208|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_04650 45f6b65a81220d6a3c9c1057c647767d 125 Hamap MF_00512 30S ribosomal protein S6e [rps6e]. 2 125 18.496 T 23-10-2018 IPR020924 Ribosomal protein S6e, archaeal GO:0003735|GO:0005840|GO:0006412 A0127_04650 45f6b65a81220d6a3c9c1057c647767d 125 SMART SM01405 4 124 6.7E-55 T 23-10-2018 IPR001377 Ribosomal protein S6e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-166208|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_03625 cb8487a2aba01d476affc23f2bfd1bfe 209 Gene3D G3DSA:3.40.50.1000 3 187 1.7E-54 T 23-10-2018 IPR023214 HAD superfamily A0127_03625 cb8487a2aba01d476affc23f2bfd1bfe 209 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 4 174 7.0E-33 T 23-10-2018 A0127_03625 cb8487a2aba01d476affc23f2bfd1bfe 209 Gene3D G3DSA:1.10.150.210 14 75 1.7E-54 T 23-10-2018 IPR023190 Phosphoserine phosphatase, domain 2 GO:0004647|GO:0006564 KEGG: 00260+3.1.3.3|KEGG: 00680+3.1.3.3|Reactome: R-HSA-977347 A0127_03625 cb8487a2aba01d476affc23f2bfd1bfe 209 SUPERFAMILY SSF56784 2 204 8.14E-43 T 23-10-2018 IPR036412 HAD-like superfamily A0127_03625 cb8487a2aba01d476affc23f2bfd1bfe 209 TIGRFAM TIGR01491 HAD-SF-IB-PSPlk: phosphoserine phosphatase-like hydrolase, archaeal 1 183 1.7E-57 T 23-10-2018 IPR006386 HAD-superfamily hydrolase, subfamily IB, PSPase-like, archaeal A0127_03625 cb8487a2aba01d476affc23f2bfd1bfe 209 Pfam PF12710 haloacid dehalogenase-like hydrolase 5 172 6.7E-21 T 23-10-2018 A0127_02240 46677312459740a12b3153430007b22a 196 Pfam PF07826 IMP cyclohydrolase-like protein 3 187 3.1E-54 T 23-10-2018 IPR020600 Inosine monophosphate cyclohydrolase-like GO:0003937|GO:0006164|GO:0006188 KEGG: 00230+3.5.4.10|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 A0127_02240 46677312459740a12b3153430007b22a 196 Hamap MF_00705 IMP cyclohydrolase [purO]. 1 196 70.522 T 23-10-2018 IPR010191 IMP cyclohydrolase GO:0003937|GO:0006164|GO:0006188 KEGG: 00230+3.5.4.10|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 A0127_02240 46677312459740a12b3153430007b22a 196 SUPERFAMILY SSF75569 2 195 1.11E-67 T 23-10-2018 IPR036795 Inosine monophosphate cyclohydrolase-like superfamily GO:0003937|GO:0006164|GO:0006188 KEGG: 00230+3.5.4.10|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 A0127_02240 46677312459740a12b3153430007b22a 196 TIGRFAM TIGR01922 purO_arch: IMP cyclohydrolase 3 194 8.3E-51 T 23-10-2018 IPR010191 IMP cyclohydrolase GO:0003937|GO:0006164|GO:0006188 KEGG: 00230+3.5.4.10|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 A0127_02240 46677312459740a12b3153430007b22a 196 Gene3D G3DSA:3.60.20.20 2 196 1.3E-56 T 23-10-2018 IPR036795 Inosine monophosphate cyclohydrolase-like superfamily GO:0003937|GO:0006164|GO:0006188 KEGG: 00230+3.5.4.10|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 A0127_02240 46677312459740a12b3153430007b22a 196 PIRSF PIRSF004866 2 196 5.5E-77 T 23-10-2018 IPR010191 IMP cyclohydrolase GO:0003937|GO:0006164|GO:0006188 KEGG: 00230+3.5.4.10|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 A0127_09460 bb50f8da9106fc3192b73d114e535e79 165 Pfam PF13247 4Fe-4S dicluster domain 41 134 6.9E-28 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A0127_09460 bb50f8da9106fc3192b73d114e535e79 165 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 79 90 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A0127_09460 bb50f8da9106fc3192b73d114e535e79 165 Pfam PF12800 4Fe-4S binding domain 11 25 0.0018 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A0127_09460 bb50f8da9106fc3192b73d114e535e79 165 SUPERFAMILY SSF54862 1 143 4.92E-53 T 23-10-2018 A0127_09460 bb50f8da9106fc3192b73d114e535e79 165 Gene3D G3DSA:3.30.70.20 29 161 5.4E-42 T 23-10-2018 A0127_09460 bb50f8da9106fc3192b73d114e535e79 165 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 13 24 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A0127_07605 78508a71cd990615bbd40abf29e85aec 90 ProSitePatterns PS01145 Ribosomal protein L34e signature. 7 20 - T 23-10-2018 IPR018065 Ribosomal protein L34e, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_07605 78508a71cd990615bbd40abf29e85aec 90 Gene3D G3DSA:3.40.1800.40 29 88 4.2E-10 T 23-10-2018 IPR038562 Ribosomal protein L34Ae superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_07605 78508a71cd990615bbd40abf29e85aec 90 Hamap MF_00349 50S ribosomal protein L34e [rpl34e]. 1 86 29.0 T 23-10-2018 IPR008195 Ribosomal protein L34Ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_07605 78508a71cd990615bbd40abf29e85aec 90 PRINTS PR01250 Ribosomal protein L34 signature 56 78 9.7E-18 T 23-10-2018 IPR008195 Ribosomal protein L34Ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_07605 78508a71cd990615bbd40abf29e85aec 90 PRINTS PR01250 Ribosomal protein L34 signature 36 46 9.7E-18 T 23-10-2018 IPR008195 Ribosomal protein L34Ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_07605 78508a71cd990615bbd40abf29e85aec 90 PRINTS PR01250 Ribosomal protein L34 signature 5 18 9.7E-18 T 23-10-2018 IPR008195 Ribosomal protein L34Ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_07605 78508a71cd990615bbd40abf29e85aec 90 PRINTS PR01250 Ribosomal protein L34 signature 18 35 9.7E-18 T 23-10-2018 IPR008195 Ribosomal protein L34Ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_07605 78508a71cd990615bbd40abf29e85aec 90 Pfam PF01199 Ribosomal protein L34e 3 83 7.9E-25 T 23-10-2018 IPR008195 Ribosomal protein L34Ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_05430 321067834b710265c8e98ed735852200 1127 SUPERFAMILY SSF82866 533 738 5.89E-27 T 23-10-2018 A0127_05430 321067834b710265c8e98ed735852200 1127 Pfam PF03176 MMPL family 534 748 5.5E-37 T 23-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 A0127_05430 321067834b710265c8e98ed735852200 1127 Pfam PF03176 MMPL family 799 1116 8.1E-27 T 23-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 A0127_05430 321067834b710265c8e98ed735852200 1127 SUPERFAMILY SSF82866 954 1116 3.53E-20 T 23-10-2018 A0127_05430 321067834b710265c8e98ed735852200 1127 Gene3D G3DSA:1.20.1640.10 555 738 3.1E-12 T 23-10-2018 A0127_01395 6af0857fdc100909c923851520741b2e 246 Gene3D G3DSA:3.40.50.300 1 242 6.6E-57 T 23-10-2018 A0127_01395 6af0857fdc100909c923851520741b2e 246 TIGRFAM TIGR01978 sufC: FeS assembly ATPase SufC 2 239 3.0E-84 T 23-10-2018 IPR010230 FeS cluster assembly SUF system, ATPase SufC GO:0005524 A0127_01395 6af0857fdc100909c923851520741b2e 246 SMART SM00382 26 219 1.5E-8 T 23-10-2018 IPR003593 AAA+ ATPase domain A0127_01395 6af0857fdc100909c923851520741b2e 246 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A0127_01395 6af0857fdc100909c923851520741b2e 246 SUPERFAMILY SSF52540 2 225 1.3E-47 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_01395 6af0857fdc100909c923851520741b2e 246 Pfam PF00005 ABC transporter 17 167 1.7E-22 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A0127_03885 865ad0be2beb80a06846b61b0f713e8f 613 Pfam PF13597 Anaerobic ribonucleoside-triphosphate reductase 22 611 5.0E-150 T 23-10-2018 IPR012833 Ribonucleoside-triphosphate reductase, anaerobic GO:0006260|GO:0008998|GO:0016491|GO:0055114 KEGG: 00230+1.1.98.6|KEGG: 00240+1.1.98.6|MetaCyc: PWY-7187|MetaCyc: PWY-7220|MetaCyc: PWY-7222 A0127_03885 865ad0be2beb80a06846b61b0f713e8f 613 TIGRFAM TIGR02487 NrdD: anaerobic ribonucleoside-triphosphate reductase 22 610 7.3E-157 T 23-10-2018 IPR012833 Ribonucleoside-triphosphate reductase, anaerobic GO:0006260|GO:0008998|GO:0016491|GO:0055114 KEGG: 00230+1.1.98.6|KEGG: 00240+1.1.98.6|MetaCyc: PWY-7187|MetaCyc: PWY-7220|MetaCyc: PWY-7222 A0127_03885 865ad0be2beb80a06846b61b0f713e8f 613 SUPERFAMILY SSF51998 23 595 1.4E-127 T 23-10-2018 A0127_03885 865ad0be2beb80a06846b61b0f713e8f 613 Gene3D G3DSA:3.20.70.20 33 593 5.7E-68 T 23-10-2018 A0127_07200 c0fa1674db0eccb767e3d840acbb3d64 255 Gene3D G3DSA:3.60.15.10 3 245 2.3E-45 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A0127_07200 c0fa1674db0eccb767e3d840acbb3d64 255 SUPERFAMILY SSF56281 34 235 4.72E-35 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A0127_07200 c0fa1674db0eccb767e3d840acbb3d64 255 SMART SM00849 39 228 1.8E-23 T 23-10-2018 IPR001279 Metallo-beta-lactamase A0127_07200 c0fa1674db0eccb767e3d840acbb3d64 255 Pfam PF00753 Metallo-beta-lactamase superfamily 38 228 8.0E-20 T 23-10-2018 IPR001279 Metallo-beta-lactamase A0127_07620 90438adacfef869e5c96e0717979f6ac 236 SUPERFAMILY SSF51735 1 211 4.24E-52 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A0127_07620 90438adacfef869e5c96e0717979f6ac 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 145 164 7.6E-14 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A0127_07620 90438adacfef869e5c96e0717979f6ac 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 74 85 7.6E-14 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A0127_07620 90438adacfef869e5c96e0717979f6ac 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 7.6E-14 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A0127_07620 90438adacfef869e5c96e0717979f6ac 236 Gene3D G3DSA:3.40.50.720 1 234 2.4E-55 T 23-10-2018 A0127_07620 90438adacfef869e5c96e0717979f6ac 236 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 145 164 4.8E-5 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A0127_07620 90438adacfef869e5c96e0717979f6ac 236 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 74 85 4.8E-5 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A0127_07620 90438adacfef869e5c96e0717979f6ac 236 Pfam PF00106 short chain dehydrogenase 2 184 1.6E-41 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A0127_02670 9c9e769f309561149870b0f897a3c4cb 293 PRINTS PR00146 Dihydrodipicolinate synthase signature 128 145 3.0E-20 T 23-10-2018 IPR002220 DapA-like GO:0016829 A0127_02670 9c9e769f309561149870b0f897a3c4cb 293 PRINTS PR00146 Dihydrodipicolinate synthase signature 35 56 3.0E-20 T 23-10-2018 IPR002220 DapA-like GO:0016829 A0127_02670 9c9e769f309561149870b0f897a3c4cb 293 PRINTS PR00146 Dihydrodipicolinate synthase signature 71 89 3.0E-20 T 23-10-2018 IPR002220 DapA-like GO:0016829 A0127_02670 9c9e769f309561149870b0f897a3c4cb 293 PRINTS PR00146 Dihydrodipicolinate synthase signature 103 119 3.0E-20 T 23-10-2018 IPR002220 DapA-like GO:0016829 A0127_02670 9c9e769f309561149870b0f897a3c4cb 293 Gene3D G3DSA:3.20.20.70 1 291 4.2E-97 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A0127_02670 9c9e769f309561149870b0f897a3c4cb 293 SMART SM01130 1 291 6.1E-101 T 23-10-2018 IPR002220 DapA-like GO:0016829 A0127_02670 9c9e769f309561149870b0f897a3c4cb 293 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 5 289 3.7E-62 T 23-10-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 A0127_02670 9c9e769f309561149870b0f897a3c4cb 293 Pfam PF00701 Dihydrodipicolinate synthetase family 2 289 1.4E-70 T 23-10-2018 IPR002220 DapA-like GO:0016829 A0127_02670 9c9e769f309561149870b0f897a3c4cb 293 SUPERFAMILY SSF51569 2 291 7.43E-89 T 23-10-2018 A0127_02670 9c9e769f309561149870b0f897a3c4cb 293 PIRSF PIRSF001365 1 293 1.0E-87 T 23-10-2018 IPR002220 DapA-like GO:0016829 A0127_09120 80f2d8d13c88c5c22f8a81617ffaf1f2 159 Gene3D G3DSA:3.40.1600.10 1 156 6.7E-72 T 23-10-2018 IPR036807 PH1570-like superfamily A0127_09120 80f2d8d13c88c5c22f8a81617ffaf1f2 159 SUPERFAMILY SSF159902 1 155 3.4E-73 T 23-10-2018 A0127_09120 80f2d8d13c88c5c22f8a81617ffaf1f2 159 Pfam PF09638 Ph1570 protein 1 155 1.4E-87 T 23-10-2018 IPR023110 PH1570-like domain A0127_09840 2229a7ce2804e740058d28bd2d4107d8 215 Hamap MF_00480_A 30S ribosomal protein S7 [rpsG]. 15 215 37.878 T 23-10-2018 IPR026018 Ribosomal protein S7, archaeal A0127_09840 2229a7ce2804e740058d28bd2d4107d8 215 TIGRFAM TIGR01028 uS7_euk_arch: ribosomal protein uS7 14 215 1.6E-88 T 23-10-2018 IPR005716 Ribosomal protein S5/S7, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_09840 2229a7ce2804e740058d28bd2d4107d8 215 PIRSF PIRSF002122 1 215 3.0E-47 T 23-10-2018 IPR000235 Ribosomal protein S5/S7 GO:0006412 A0127_09840 2229a7ce2804e740058d28bd2d4107d8 215 Pfam PF00177 Ribosomal protein S7p/S5e 55 215 6.0E-38 T 23-10-2018 IPR023798 Ribosomal protein S7 domain A0127_09840 2229a7ce2804e740058d28bd2d4107d8 215 Gene3D G3DSA:1.10.455.10 15 215 1.2E-78 T 23-10-2018 IPR036823 Ribosomal protein S7 domain superfamily A0127_09840 2229a7ce2804e740058d28bd2d4107d8 215 SUPERFAMILY SSF47973 16 215 2.09E-62 T 23-10-2018 IPR036823 Ribosomal protein S7 domain superfamily A0127_02495 6b289a6d0079bf4ac194aa479921053b 86 Pfam PF01402 Ribbon-helix-helix protein, copG family 6 41 2.3E-6 T 23-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 A0127_08525 4324cdf67e72d84874218269ed3cd8bf 136 Pfam PF01985 CRS1 / YhbY (CRM) domain 5 91 1.0E-11 T 23-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 A0127_08525 4324cdf67e72d84874218269ed3cd8bf 136 ProDom PD010559 RNA-BINDING YHBY UPF0044 PREDICTED RNA RIBOSOMAL CONTAINING KH BINDING DOMAIN 10 94 8.0E-41 T 23-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 A0127_08525 4324cdf67e72d84874218269ed3cd8bf 136 SMART SM01103 4 91 2.2E-24 T 23-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 A0127_08525 4324cdf67e72d84874218269ed3cd8bf 136 SUPERFAMILY SSF75471 4 99 4.71E-17 T 23-10-2018 IPR035920 YhbY-like superfamily A0127_08525 4324cdf67e72d84874218269ed3cd8bf 136 Gene3D G3DSA:3.30.110.60 4 112 5.1E-20 T 23-10-2018 IPR035920 YhbY-like superfamily A0127_09070 81ba78460f8dd22601c892067ae7d487 264 Pfam PF01255 Putative undecaprenyl diphosphate synthase 41 263 1.0E-84 T 23-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 A0127_09070 81ba78460f8dd22601c892067ae7d487 264 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 209 226 - T 23-10-2018 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199|Reactome: R-HSA-4755609 A0127_09070 81ba78460f8dd22601c892067ae7d487 264 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 34 263 3.1E-89 T 23-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 A0127_09070 81ba78460f8dd22601c892067ae7d487 264 Gene3D G3DSA:3.40.1180.10 18 264 2.8E-104 T 23-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 A0127_09070 81ba78460f8dd22601c892067ae7d487 264 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 34 264 40.367 T 23-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 A0127_09070 81ba78460f8dd22601c892067ae7d487 264 SUPERFAMILY SSF64005 31 259 2.62E-89 T 23-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 A0127_01765 587a6d24347496db0a9d7d7dea9335aa 288 PIRSF PIRSF016175 7 287 1.6E-138 T 23-10-2018 IPR016648 Uncharacterised conserved protein UCP016175, prenyltransferase beta-subunit-related A0127_01765 587a6d24347496db0a9d7d7dea9335aa 288 SUPERFAMILY SSF48239 8 252 4.71E-19 T 23-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid A0127_02650 8d400ebb97ded6253f87b31df5d3f1f5 144 SUPERFAMILY SSF52242 5 133 3.14E-49 T 23-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 A0127_02650 8d400ebb97ded6253f87b31df5d3f1f5 144 Pfam PF02310 B12 binding domain 8 121 1.6E-24 T 23-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 A0127_02650 8d400ebb97ded6253f87b31df5d3f1f5 144 Gene3D G3DSA:3.40.50.280 1 144 7.4E-58 T 23-10-2018 A0127_02650 8d400ebb97ded6253f87b31df5d3f1f5 144 TIGRFAM TIGR00640 acid_CoA_mut_C: methylmalonyl-CoA mutase C-terminal domain 6 138 5.6E-61 T 23-10-2018 IPR006159 Methylmalonyl-CoA mutase, C-terminal GO:0016853 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 A0127_00775 5f349615a5d15024f6671c805dc4b388 207 SUPERFAMILY SSF103039 1 198 1.16E-41 T 23-10-2018 IPR028976 CheC-like superfamily A0127_00775 5f349615a5d15024f6671c805dc4b388 207 Pfam PF04509 CheC-like family 10 42 1.2E-4 T 23-10-2018 IPR007597 CheC-like protein GO:0016787 A0127_00775 5f349615a5d15024f6671c805dc4b388 207 Gene3D G3DSA:3.40.1550.10 1 200 6.9E-45 T 23-10-2018 IPR028976 CheC-like superfamily A0127_00775 5f349615a5d15024f6671c805dc4b388 207 Pfam PF13690 Chemotaxis phosphatase CheX 64 145 1.7E-7 T 23-10-2018 IPR028051 Chemotaxis phosphatase CheX-like domain A0127_09500 4d54e5be38ec95399acc7afd59b58b17 146 Gene3D G3DSA:3.30.460.10 4 119 4.4E-8 T 23-10-2018 A0127_09500 4d54e5be38ec95399acc7afd59b58b17 146 SUPERFAMILY SSF81301 4 118 2.67E-7 T 23-10-2018 A0127_02690 6dd4c22aaf82920236a4e0d21ed8fd54 81 Pfam PF04457 Protein of unknown function (DUF504) 26 77 2.6E-15 T 23-10-2018 IPR007547 Uncharacterised protein family UPF0248 A0127_02690 6dd4c22aaf82920236a4e0d21ed8fd54 81 Hamap MF_01245 UPF0248 protein . 10 79 19.116 T 23-10-2018 IPR007547 Uncharacterised protein family UPF0248 A0127_02925 ca7aa54b113803cceb252632908e6394 413 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 325 351 0.0025 T 23-10-2018 IPR001451 Hexapeptide repeat A0127_02925 ca7aa54b113803cceb252632908e6394 413 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 352 383 4.1E-4 T 23-10-2018 IPR001451 Hexapeptide repeat A0127_02925 ca7aa54b113803cceb252632908e6394 413 Gene3D G3DSA:2.160.10.10 290 351 2.0E-5 T 23-10-2018 A0127_02925 ca7aa54b113803cceb252632908e6394 413 Gene3D G3DSA:3.90.550.10 3 272 2.0E-67 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A0127_02925 ca7aa54b113803cceb252632908e6394 413 Gene3D G3DSA:2.160.10.10 352 410 4.0E-10 T 23-10-2018 A0127_02925 ca7aa54b113803cceb252632908e6394 413 SUPERFAMILY SSF53448 1 382 1.2E-65 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A0127_02925 ca7aa54b113803cceb252632908e6394 413 Pfam PF00483 Nucleotidyl transferase 4 254 6.9E-42 T 23-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 A0127_02925 ca7aa54b113803cceb252632908e6394 413 SUPERFAMILY SSF51161 227 411 2.36E-18 T 23-10-2018 IPR011004 Trimeric LpxA-like superfamily A0127_07595 e8cc8bfe4dfc50bf283e46050ae43bf3 196 SUPERFAMILY SSF52540 1 188 1.57E-21 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_07595 e8cc8bfe4dfc50bf283e46050ae43bf3 196 Pfam PF13207 AAA domain 8 144 8.9E-36 T 23-10-2018 A0127_07595 e8cc8bfe4dfc50bf283e46050ae43bf3 196 Gene3D G3DSA:3.40.50.300 3 189 3.7E-57 T 23-10-2018 A0127_07595 e8cc8bfe4dfc50bf283e46050ae43bf3 196 Hamap MF_00234 Adenylate kinase [adkA]. 3 189 44.173 T 23-10-2018 IPR023477 Adenylate kinase AdkA GO:0004017 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 A0127_05595 8ae19aa335987366c377b17d33757ab3 212 Pfam PF02676 Methyltransferase TYW3 3 184 5.9E-40 T 23-10-2018 IPR003827 tRNA wybutosine-synthesizing protein MetaCyc: PWY-7286|Reactome: R-HSA-6782861 A0127_05595 8ae19aa335987366c377b17d33757ab3 212 SUPERFAMILY SSF111278 2 183 1.44E-50 T 23-10-2018 IPR036602 tRNA wybutosine-synthesizing-like superfamily MetaCyc: PWY-7286|Reactome: R-HSA-6782861 A0127_05595 8ae19aa335987366c377b17d33757ab3 212 Gene3D G3DSA:3.30.1960.10 1 184 5.3E-50 T 23-10-2018 IPR036602 tRNA wybutosine-synthesizing-like superfamily MetaCyc: PWY-7286|Reactome: R-HSA-6782861 A0127_05595 8ae19aa335987366c377b17d33757ab3 212 Hamap MF_00266 tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase [taw3]. 1 186 27.316 T 23-10-2018 IPR022908 tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase GO:0008175|GO:0030488|GO:0031591 MetaCyc: PWY-7286 A0127_04130 be79fb2d515d02a40cce10798536c7f8 312 SMART SM00729 26 239 1.9E-22 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A0127_04130 be79fb2d515d02a40cce10798536c7f8 312 Gene3D G3DSA:3.20.20.70 19 239 1.6E-24 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A0127_04130 be79fb2d515d02a40cce10798536c7f8 312 Pfam PF04055 Radical SAM superfamily 38 193 2.2E-10 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A0127_04130 be79fb2d515d02a40cce10798536c7f8 312 SUPERFAMILY SSF102114 18 285 8.24E-40 T 23-10-2018 A0127_01330 168274ca83172b0aee52d64148e04d85 194 Gene3D G3DSA:3.90.550.10 16 192 2.3E-10 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A0127_01330 168274ca83172b0aee52d64148e04d85 194 SUPERFAMILY SSF53448 13 144 5.0E-8 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A0127_04740 9bdb08944f565b606095e385924ebab1 420 SUPERFAMILY SSF51905 1 388 1.28E-34 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A0127_04740 9bdb08944f565b606095e385924ebab1 420 Gene3D G3DSA:3.90.660.50 83 359 1.7E-140 T 23-10-2018 A0127_04740 9bdb08944f565b606095e385924ebab1 420 Pfam PF13450 NAD(P)-binding Rossmann-like domain 5 61 4.2E-11 T 23-10-2018 A0127_04740 9bdb08944f565b606095e385924ebab1 420 Gene3D G3DSA:3.50.50.60 4 403 1.7E-140 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A0127_08685 8d843d44b14cfc5636332c8ecfd9dfaf 133 Pfam PF01989 Protein of unknown function DUF126 24 103 1.1E-36 T 23-10-2018 IPR002840 Aconitase X swivel domain, putative A0127_08685 8d843d44b14cfc5636332c8ecfd9dfaf 133 Hamap MF_00078 UPF0107 protein . 2 129 34.197 T 23-10-2018 IPR020794 Aconitase X subunit 2, archaeal, putative A0127_08685 8d843d44b14cfc5636332c8ecfd9dfaf 133 PIRSF PIRSF004966 1 131 2.7E-56 T 23-10-2018 IPR012016 Aconitase X subunit 2, putative A0127_08685 8d843d44b14cfc5636332c8ecfd9dfaf 133 Gene3D G3DSA:3.50.30.10 1 133 2.2E-51 T 23-10-2018 A0127_08685 8d843d44b14cfc5636332c8ecfd9dfaf 133 SUPERFAMILY SSF52016 1 129 9.42E-46 T 23-10-2018 A0127_08805 02c7ff78271821ee83496f5f58f6b7c7 130 Pfam PF03334 Na+/H+ antiporter subunit 11 94 9.0E-25 T 23-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 A0127_08805 02c7ff78271821ee83496f5f58f6b7c7 130 TIGRFAM TIGR01300 CPA3_mnhG_phaG: monovalent cation/proton antiporter, MnhG/PhaG subunit 10 109 1.1E-28 T 23-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 A0127_09850 c5397c92098fc1c806bbd65567cb7831 134 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 5 122 9.832 T 23-10-2018 IPR022907 VapC family GO:0004540 A0127_09850 c5397c92098fc1c806bbd65567cb7831 134 Gene3D G3DSA:3.40.50.1010 1 126 6.9E-25 T 23-10-2018 A0127_09850 c5397c92098fc1c806bbd65567cb7831 134 Pfam PF01850 PIN domain 6 113 2.8E-14 T 23-10-2018 IPR002716 PIN domain A0127_09850 c5397c92098fc1c806bbd65567cb7831 134 SUPERFAMILY SSF88723 3 127 4.21E-28 T 23-10-2018 IPR029060 PIN-like domain superfamily A0127_09475 d463d3573a6e5b6aafd74dc24ace18ca 306 Pfam PF00146 NADH dehydrogenase 15 299 1.5E-42 T 23-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A0127_09475 d463d3573a6e5b6aafd74dc24ace18ca 306 ProSitePatterns PS00668 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. 192 205 - T 23-10-2018 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A0127_04325 bc08c93492af8df4754b11a505a6644f 199 TIGRFAM TIGR03634 arc_protsome_B: proteasome endopeptidase complex, archaeal, beta subunit 6 190 1.2E-77 T 23-10-2018 IPR019983 Peptidase T1A, proteasome beta-subunit, archaeal GO:0004175|GO:0005839|GO:0051603 A0127_04325 bc08c93492af8df4754b11a505a6644f 199 Hamap MF_02113_A Proteasome subunit beta [prcB]. 2 198 34.822 T 23-10-2018 IPR019983 Peptidase T1A, proteasome beta-subunit, archaeal GO:0004175|GO:0005839|GO:0051603 A0127_04325 bc08c93492af8df4754b11a505a6644f 199 PRINTS PR00141 Proteasome component signature 145 156 1.9E-5 T 23-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 A0127_04325 bc08c93492af8df4754b11a505a6644f 199 PRINTS PR00141 Proteasome component signature 134 145 1.9E-5 T 23-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 A0127_04325 bc08c93492af8df4754b11a505a6644f 199 PRINTS PR00141 Proteasome component signature 14 29 1.9E-5 T 23-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 A0127_04325 bc08c93492af8df4754b11a505a6644f 199 Gene3D G3DSA:3.60.20.10 2 198 1.9E-62 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A0127_04325 bc08c93492af8df4754b11a505a6644f 199 SUPERFAMILY SSF56235 4 192 8.96E-59 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A0127_04325 bc08c93492af8df4754b11a505a6644f 199 Pfam PF00227 Proteasome subunit 4 184 3.5E-52 T 23-10-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 A0127_04440 8712c61fb589ddb511fd0b884b712111 195 Pfam PF14470 Bacterial PH domain 17 109 3.0E-21 T 23-10-2018 IPR039519 YokE-like, PH domain A0127_04440 8712c61fb589ddb511fd0b884b712111 195 Pfam PF09851 Short C-terminal domain 165 192 3.0E-11 T 23-10-2018 IPR018649 SHOCT domain A0127_03430 6de9b075a0bb1c6f55f2e6241ccbba3a 384 Gene3D G3DSA:3.40.50.2000 204 364 9.3E-51 T 23-10-2018 A0127_03430 6de9b075a0bb1c6f55f2e6241ccbba3a 384 Pfam PF00534 Glycosyl transferases group 1 192 358 2.4E-47 T 23-10-2018 IPR001296 Glycosyl transferase, family 1 A0127_03430 6de9b075a0bb1c6f55f2e6241ccbba3a 384 Pfam PF13439 Glycosyltransferase Family 4 14 182 1.1E-31 T 23-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 A0127_03430 6de9b075a0bb1c6f55f2e6241ccbba3a 384 SUPERFAMILY SSF53756 1 381 4.91E-103 T 23-10-2018 A0127_03430 6de9b075a0bb1c6f55f2e6241ccbba3a 384 Gene3D G3DSA:3.40.50.2000 1 203 3.3E-46 T 23-10-2018 A0127_10235 1c1505c5dcb916f4c1197f3a85389acf 110 Pfam PF12840 Helix-turn-helix domain 34 81 3.1E-6 T 23-10-2018 A0127_10235 1c1505c5dcb916f4c1197f3a85389acf 110 SUPERFAMILY SSF46785 18 104 7.91E-10 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A0127_10235 1c1505c5dcb916f4c1197f3a85389acf 110 Gene3D G3DSA:1.10.10.10 17 101 1.8E-12 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A0127_06595 770a7672ef3a3e02d508c52db504e29a 333 Gene3D G3DSA:3.90.25.10 177 309 1.1E-135 T 23-10-2018 A0127_06595 770a7672ef3a3e02d508c52db504e29a 333 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 304 3.0E-86 T 23-10-2018 IPR016040 NAD(P)-binding domain A0127_06595 770a7672ef3a3e02d508c52db504e29a 333 TIGRFAM TIGR01181 dTDP_gluc_dehyt: dTDP-glucose 4,6-dehydratase 2 318 3.7E-163 T 23-10-2018 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|KEGG: 00525+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 A0127_06595 770a7672ef3a3e02d508c52db504e29a 333 SUPERFAMILY SSF51735 1 320 1.06E-97 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A0127_06595 770a7672ef3a3e02d508c52db504e29a 333 Gene3D G3DSA:3.40.50.720 4 294 1.1E-135 T 23-10-2018 A0127_06760 d1cf00d8214601f7fb1db99b33e9e795 175 PIRSF PIRSF006533 1 173 4.6E-54 T 23-10-2018 IPR007164 Protein of unknown function DUF359 A0127_06760 d1cf00d8214601f7fb1db99b33e9e795 175 Hamap MF_00590 UPF0218 protein . 5 171 29.71 T 23-10-2018 IPR007164 Protein of unknown function DUF359 A0127_06760 d1cf00d8214601f7fb1db99b33e9e795 175 Pfam PF04019 Protein of unknown function (DUF359) 48 169 7.9E-39 T 23-10-2018 IPR007164 Protein of unknown function DUF359 A0127_09560 db065f2daec505d0c47bf184a327d381 160 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 23 86 5.0E-9 T 23-10-2018 IPR002831 Transcription regulator TrmB, N-terminal A0127_09560 db065f2daec505d0c47bf184a327d381 160 PIRSF PIRSF006707 4 159 2.1E-31 T 23-10-2018 IPR026282 DNA-binding protein, MJ1563 type A0127_09560 db065f2daec505d0c47bf184a327d381 160 Gene3D G3DSA:1.10.10.10 3 85 1.7E-17 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A0127_09560 db065f2daec505d0c47bf184a327d381 160 SUPERFAMILY SSF46785 9 133 8.31E-18 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A0127_05000 56b5aee867d486d8bdbc4953891d7432 105 Pfam PF14697 4Fe-4S dicluster domain 47 100 8.8E-11 T 23-10-2018 A0127_05000 56b5aee867d486d8bdbc4953891d7432 105 TIGRFAM TIGR02179 PorD_KorD: 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate family 32 104 1.2E-33 T 23-10-2018 IPR011898 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate GO:0016625|GO:0051539 A0127_05000 56b5aee867d486d8bdbc4953891d7432 105 SUPERFAMILY SSF54862 32 103 5.76E-25 T 23-10-2018 A0127_05000 56b5aee867d486d8bdbc4953891d7432 105 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 83 94 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A0127_05000 56b5aee867d486d8bdbc4953891d7432 105 Gene3D G3DSA:3.30.70.20 32 72 3.2E-6 T 23-10-2018 A0127_05000 56b5aee867d486d8bdbc4953891d7432 105 Gene3D G3DSA:3.30.70.20 73 105 6.0E-9 T 23-10-2018 A0127_02535 66a21daa2d96ebbf29d23a81675155f2 309 Pfam PF13732 Domain of unknown function (DUF4162) 218 302 1.6E-8 T 23-10-2018 IPR025302 Domain of unknown function DUF4162 A0127_02535 66a21daa2d96ebbf29d23a81675155f2 309 SUPERFAMILY SSF52540 6 227 5.33E-62 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_02535 66a21daa2d96ebbf29d23a81675155f2 309 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A0127_02535 66a21daa2d96ebbf29d23a81675155f2 309 Pfam PF00005 ABC transporter 22 165 2.4E-31 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A0127_02535 66a21daa2d96ebbf29d23a81675155f2 309 SMART SM00382 30 213 7.1E-14 T 23-10-2018 IPR003593 AAA+ ATPase domain A0127_02535 66a21daa2d96ebbf29d23a81675155f2 309 Gene3D G3DSA:3.40.50.300 1 239 8.8E-68 T 23-10-2018 A0127_07090 981209f672fbe26bb4b8ec36b8edd819 127 TIGRFAM TIGR01195 oadG_fam: sodium pump decarboxylases, gamma subunit 4 86 1.3E-13 T 23-10-2018 IPR005899 Sodium ion-translocating decarboxylase GO:0008948|GO:0015081|GO:0016020|GO:0036376 KEGG: 00620+4.1.1.3 A0127_07090 981209f672fbe26bb4b8ec36b8edd819 127 Pfam PF04277 Oxaloacetate decarboxylase, gamma chain 7 85 3.7E-14 T 23-10-2018 IPR005899 Sodium ion-translocating decarboxylase GO:0008948|GO:0015081|GO:0016020|GO:0036376 KEGG: 00620+4.1.1.3 A0127_06690 cd0e460444b7b324db0fc53b27563195 331 Pfam PF00483 Nucleotidyl transferase 2 233 6.3E-38 T 23-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 A0127_06690 cd0e460444b7b324db0fc53b27563195 331 Gene3D G3DSA:2.160.10.10 239 330 1.1E-6 T 23-10-2018 A0127_06690 cd0e460444b7b324db0fc53b27563195 331 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 253 281 0.001 T 23-10-2018 IPR001451 Hexapeptide repeat A0127_06690 cd0e460444b7b324db0fc53b27563195 331 SUPERFAMILY SSF53448 1 286 9.24E-56 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A0127_06690 cd0e460444b7b324db0fc53b27563195 331 Gene3D G3DSA:3.90.550.10 1 238 4.8E-54 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A0127_07475 ec8b8efb41cf3583c6f0c952ebaabfd6 255 SUPERFAMILY SSF52166 1 252 1.44E-73 T 23-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 A0127_07475 ec8b8efb41cf3583c6f0c952ebaabfd6 255 ProSitePatterns PS00939 Ribosomal protein L1e signature. 106 132 - T 23-10-2018 IPR013000 Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_07475 ec8b8efb41cf3583c6f0c952ebaabfd6 255 Hamap MF_01328_A 50S ribosomal protein L4 [rplD]. 2 253 44.563 T 23-10-2018 IPR019970 Ribosomal protein L4 GO:0003735|GO:0005840|GO:0006412|GO:0019843 A0127_07475 ec8b8efb41cf3583c6f0c952ebaabfd6 255 Pfam PF00573 Ribosomal protein L4/L1 family 16 252 1.1E-49 T 23-10-2018 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 A0127_07475 ec8b8efb41cf3583c6f0c952ebaabfd6 255 Gene3D G3DSA:3.40.1370.10 1 255 3.2E-99 T 23-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 A0127_07475 ec8b8efb41cf3583c6f0c952ebaabfd6 255 TIGRFAM TIGR03672 rpl4p_arch: 50S ribosomal protein uL4 1 252 1.8E-116 T 23-10-2018 IPR019970 Ribosomal protein L4 GO:0003735|GO:0005840|GO:0006412|GO:0019843 A0127_02150 65d3e0249eb93941dc1f5af907b933b5 90 Pfam PF04066 Multiple resistance and pH regulation protein F (MrpF / PhaF) 35 87 1.3E-14 T 23-10-2018 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 A0127_07735 e790b7841b9cf84220f805156795fe6b 253 Gene3D G3DSA:3.60.21.10 1 253 1.5E-49 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like A0127_07735 e790b7841b9cf84220f805156795fe6b 253 SUPERFAMILY SSF56300 1 252 1.39E-57 T 23-10-2018 A0127_09490 aef04f13e33a3a8ef5b41f17d9a3eefc 279 SUPERFAMILY SSF56770 6 158 2.49E-46 T 23-10-2018 A0127_09490 aef04f13e33a3a8ef5b41f17d9a3eefc 279 Gene3D G3DSA:3.40.50.12280 2 166 1.9E-44 T 23-10-2018 A0127_09490 aef04f13e33a3a8ef5b41f17d9a3eefc 279 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 19 144 1.6E-26 T 23-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A0127_04155 8099cb114a9598641bc6ccfb465c20c5 383 Gene3D G3DSA:3.30.420.40 148 313 5.1E-8 T 23-10-2018 A0127_04155 8099cb114a9598641bc6ccfb465c20c5 383 SUPERFAMILY SSF53067 4 319 3.99E-13 T 23-10-2018 A0127_04155 8099cb114a9598641bc6ccfb465c20c5 383 PIRSF PIRSF009433 1 380 3.3E-160 T 23-10-2018 IPR009927 Protein of unknown function DUF1464 A0127_04155 8099cb114a9598641bc6ccfb465c20c5 383 Pfam PF07318 Protein of unknown function (DUF1464) 6 369 3.1E-102 T 23-10-2018 IPR009927 Protein of unknown function DUF1464 A0127_10285 0af284753c59497d813169f8bfb0e5f4 69 Gene3D G3DSA:1.10.620.20 1 66 9.5E-12 T 23-10-2018 IPR012348 Ribonucleotide reductase-like GO:0016491|GO:0055114 Reactome: R-HSA-499943 A0127_10285 0af284753c59497d813169f8bfb0e5f4 69 SMART SM00746 4 41 8.2E-9 T 23-10-2018 IPR011017 TRASH domain A0127_10285 0af284753c59497d813169f8bfb0e5f4 69 SUPERFAMILY SSF47240 4 47 8.11E-10 T 23-10-2018 IPR009078 Ferritin-like superfamily A0127_10285 0af284753c59497d813169f8bfb0e5f4 69 Pfam PF04945 YHS domain 3 45 1.2E-19 T 23-10-2018 IPR007029 YHS domain A0127_07815 e90508ac791c9bfc471696ca1faab523 354 Gene3D G3DSA:3.40.50.1100 46 349 3.5E-81 T 23-10-2018 A0127_07815 e90508ac791c9bfc471696ca1faab523 354 Gene3D G3DSA:3.40.50.1100 91 186 3.5E-81 T 23-10-2018 A0127_07815 e90508ac791c9bfc471696ca1faab523 354 SUPERFAMILY SSF53686 2 352 3.4E-74 T 23-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme A0127_07815 e90508ac791c9bfc471696ca1faab523 354 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 76 345 5.2E-61 T 23-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme A0127_01000 360ac6c85558ea409eb2e71bc10719bc 294 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 61 204 2.6E-31 T 23-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 A0127_01000 360ac6c85558ea409eb2e71bc10719bc 294 Gene3D G3DSA:3.40.50.970 57 221 2.5E-25 T 23-10-2018 A0127_01000 360ac6c85558ea409eb2e71bc10719bc 294 SUPERFAMILY SSF52518 20 279 8.54E-80 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold A0127_01000 360ac6c85558ea409eb2e71bc10719bc 294 Pfam PF12367 Pyruvate ferredoxin oxidoreductase beta subunit C terminal 208 269 3.8E-25 T 23-10-2018 IPR032686 Pyruvate ferredoxin oxidoreductase beta subunit, C-terminal A0127_01000 360ac6c85558ea409eb2e71bc10719bc 294 TIGRFAM TIGR02177 PorB_KorB: 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate family 23 281 2.2E-110 T 23-10-2018 IPR011896 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate A0127_01225 ecba8bdfa34d1b80ba62e4edbe229ebf 1361 Pfam PF03176 MMPL family 777 974 1.6E-36 T 23-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 A0127_01225 ecba8bdfa34d1b80ba62e4edbe229ebf 1361 Pfam PF03176 MMPL family 1054 1348 9.4E-31 T 23-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 A0127_01225 ecba8bdfa34d1b80ba62e4edbe229ebf 1361 SUPERFAMILY SSF82866 1184 1346 3.4E-21 T 23-10-2018 A0127_01225 ecba8bdfa34d1b80ba62e4edbe229ebf 1361 SUPERFAMILY SSF82866 765 965 1.31E-24 T 23-10-2018 A0127_08480 596d06e77590c9a6c80d349409bce556 77 ProDom PD010302 RIBOSOMAL LX 50S RIBONUCLEOPROTEIN HL32 DIRECT SEQUENCING LXA LSU 6 51 7.0E-20 T 23-10-2018 IPR002768 50S ribosomal protein L18Ae, archaea GO:0003735|GO:0005840|GO:0006412 A0127_08480 596d06e77590c9a6c80d349409bce556 77 Hamap MF_00273 50S ribosomal protein L18Ae [rpl18a]. 3 58 21.094 T 23-10-2018 IPR028877 50S ribosomal protein L18Ae/60S ribosomal protein L20 and L18a Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_08480 596d06e77590c9a6c80d349409bce556 77 Gene3D G3DSA:3.10.20.10 3 76 1.2E-29 T 23-10-2018 A0127_08480 596d06e77590c9a6c80d349409bce556 77 SUPERFAMILY SSF160374 1 73 1.31E-25 T 23-10-2018 A0127_08480 596d06e77590c9a6c80d349409bce556 77 Pfam PF01775 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A 2 58 1.7E-12 T 23-10-2018 IPR023573 Ribosomal protein 50S-L18Ae/60S-L20/60S-L18A GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_08530 2c1f677673db1aade98e09bbf88b1fa3 888 Hamap MF_02005 Valine--tRNA ligase [valS]. 2 793 28.873 T 23-10-2018 IPR022874 Valine-tRNA ligase, type 2 GO:0004832 KEGG: 00970+6.1.1.9 A0127_08530 2c1f677673db1aade98e09bbf88b1fa3 888 PRINTS PR00986 Valyl-tRNA synthetase signature 36 47 1.6E-18 T 23-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 A0127_08530 2c1f677673db1aade98e09bbf88b1fa3 888 PRINTS PR00986 Valyl-tRNA synthetase signature 343 356 1.6E-18 T 23-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 A0127_08530 2c1f677673db1aade98e09bbf88b1fa3 888 PRINTS PR00986 Valyl-tRNA synthetase signature 448 469 1.6E-18 T 23-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 A0127_08530 2c1f677673db1aade98e09bbf88b1fa3 888 PRINTS PR00986 Valyl-tRNA synthetase signature 225 242 1.6E-18 T 23-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 A0127_08530 2c1f677673db1aade98e09bbf88b1fa3 888 PRINTS PR00986 Valyl-tRNA synthetase signature 486 504 1.6E-18 T 23-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 A0127_08530 2c1f677673db1aade98e09bbf88b1fa3 888 SUPERFAMILY SSF52374 3 579 2.6E-126 T 23-10-2018 A0127_08530 2c1f677673db1aade98e09bbf88b1fa3 888 Gene3D G3DSA:3.90.740.10 170 337 7.1E-242 T 23-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 A0127_08530 2c1f677673db1aade98e09bbf88b1fa3 888 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 14 570 5.4E-139 T 23-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 A0127_08530 2c1f677673db1aade98e09bbf88b1fa3 888 SUPERFAMILY SSF47323 586 825 2.62E-62 T 23-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 A0127_08530 2c1f677673db1aade98e09bbf88b1fa3 888 Pfam PF08264 Anticodon-binding domain of tRNA 614 762 2.1E-38 T 23-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 A0127_08530 2c1f677673db1aade98e09bbf88b1fa3 888 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 43 54 - T 23-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 A0127_08530 2c1f677673db1aade98e09bbf88b1fa3 888 TIGRFAM TIGR00422 valS: valine--tRNA ligase 3 847 8.8E-271 T 23-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 A0127_08530 2c1f677673db1aade98e09bbf88b1fa3 888 Gene3D G3DSA:1.10.730.10 2 750 7.1E-242 T 23-10-2018 A0127_08530 2c1f677673db1aade98e09bbf88b1fa3 888 SUPERFAMILY SSF50677 187 335 2.22E-51 T 23-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 A0127_08530 2c1f677673db1aade98e09bbf88b1fa3 888 Gene3D G3DSA:3.40.50.620 22 535 7.1E-242 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A0127_08945 f80a8c6854abc923abe321168ca790f4 253 SUPERFAMILY SSF102114 32 217 4.71E-12 T 23-10-2018 A0127_08945 f80a8c6854abc923abe321168ca790f4 253 Pfam PF04055 Radical SAM superfamily 31 187 1.5E-14 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A0127_08945 f80a8c6854abc923abe321168ca790f4 253 Pfam PF13353 4Fe-4S single cluster domain 29 147 2.5E-8 T 23-10-2018 A0127_08945 f80a8c6854abc923abe321168ca790f4 253 Gene3D G3DSA:3.20.20.70 4 253 8.9E-27 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A0127_08945 f80a8c6854abc923abe321168ca790f4 253 Hamap MF_00917 7-carboxy-7-deazaguanine synthase [queE]. 3 253 39.504 T 23-10-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 A0127_00760 d805214841065f82424434926b448be8 355 SMART SM00448 7 126 3.0E-29 T 23-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A0127_00760 d805214841065f82424434926b448be8 355 Gene3D G3DSA:3.40.50.2300 4 144 9.3E-38 T 23-10-2018 A0127_00760 d805214841065f82424434926b448be8 355 Hamap MF_00099 Chemotaxis response regulator protein-glutamate methylesterase [cheB]. 7 351 41.565 T 23-10-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 A0127_00760 d805214841065f82424434926b448be8 355 PIRSF PIRSF000876 4 354 2.9E-143 T 23-10-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 A0127_00760 d805214841065f82424434926b448be8 355 SUPERFAMILY SSF52738 162 348 5.1E-68 T 23-10-2018 IPR035909 Methylesterase CheB, C-terminal A0127_00760 d805214841065f82424434926b448be8 355 Gene3D G3DSA:3.40.50.180 159 349 6.7E-74 T 23-10-2018 IPR035909 Methylesterase CheB, C-terminal A0127_00760 d805214841065f82424434926b448be8 355 SUPERFAMILY SSF52172 5 146 5.27E-32 T 23-10-2018 IPR011006 CheY-like superfamily A0127_00760 d805214841065f82424434926b448be8 355 Pfam PF00072 Response regulator receiver domain 9 113 7.4E-26 T 23-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A0127_00760 d805214841065f82424434926b448be8 355 Pfam PF01339 CheB methylesterase 167 346 4.2E-63 T 23-10-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 A0127_09910 36ef3148e37fed72fd4ac1290579c43a 100 Gene3D G3DSA:1.20.1260.10 4 75 2.6E-10 T 23-10-2018 IPR012347 Ferritin-like A0127_09910 36ef3148e37fed72fd4ac1290579c43a 100 SUPERFAMILY SSF47240 6 86 8.74E-20 T 23-10-2018 IPR009078 Ferritin-like superfamily A0127_09910 36ef3148e37fed72fd4ac1290579c43a 100 Pfam PF02915 Rubrerythrin 24 91 1.6E-7 T 23-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 A0127_01475 f378d9dfc1a5225b1008fef45daa9ced 296 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 101 112 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A0127_01475 f378d9dfc1a5225b1008fef45daa9ced 296 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 71 82 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A0127_01475 f378d9dfc1a5225b1008fef45daa9ced 296 Gene3D G3DSA:3.30.70.20 69 117 2.3E-10 T 23-10-2018 A0127_01475 f378d9dfc1a5225b1008fef45daa9ced 296 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 3 266 3.9E-22 T 23-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain A0127_01475 f378d9dfc1a5225b1008fef45daa9ced 296 Pfam PF14697 4Fe-4S dicluster domain 64 118 1.6E-11 T 23-10-2018 A0127_01475 f378d9dfc1a5225b1008fef45daa9ced 296 SUPERFAMILY SSF54862 54 122 2.83E-18 T 23-10-2018 A0127_01475 f378d9dfc1a5225b1008fef45daa9ced 296 SUPERFAMILY SSF52540 1 293 1.2E-35 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_06610 24dc53b23074206c393ccf9ac8646e12 294 Pfam PF00535 Glycosyl transferase family 2 6 126 5.0E-30 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A0127_06610 24dc53b23074206c393ccf9ac8646e12 294 Gene3D G3DSA:3.90.550.10 1 241 2.6E-64 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A0127_06610 24dc53b23074206c393ccf9ac8646e12 294 SUPERFAMILY SSF53448 4 213 1.03E-59 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A0127_01430 a607daed1c83f3937f8a6dddf25c66b3 201 SUPERFAMILY SSF53146 1 117 7.59E-28 T 23-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily A0127_01430 a607daed1c83f3937f8a6dddf25c66b3 201 Gene3D G3DSA:3.30.420.130 1 118 8.4E-27 T 23-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily A0127_01430 a607daed1c83f3937f8a6dddf25c66b3 201 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 13 106 5.7E-22 T 23-10-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis A0127_10010 69ea4898961ac74c6d778eb643613f6b 136 SMART SM00418 55 133 1.5E-12 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A0127_10010 69ea4898961ac74c6d778eb643613f6b 136 Pfam PF01022 Bacterial regulatory protein, arsR family 62 108 8.6E-14 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A0127_10010 69ea4898961ac74c6d778eb643613f6b 136 SUPERFAMILY SSF46785 50 122 4.97E-19 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A0127_10010 69ea4898961ac74c6d778eb643613f6b 136 Gene3D G3DSA:1.10.10.10 42 134 8.7E-20 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A0127_10010 69ea4898961ac74c6d778eb643613f6b 136 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 57 72 5.3E-8 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A0127_10010 69ea4898961ac74c6d778eb643613f6b 136 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 89 104 5.3E-8 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A0127_08435 0303eedabd49e4e4747f8bbf53fa0304 394 Gene3D G3DSA:3.30.1380.20 251 394 2.6E-12 T 23-10-2018 A0127_08435 0303eedabd49e4e4747f8bbf53fa0304 394 SUPERFAMILY SSF52540 3 169 1.63E-12 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_08435 0303eedabd49e4e4747f8bbf53fa0304 394 Pfam PF02830 V4R domain 347 390 7.4E-13 T 23-10-2018 IPR004096 4-vinyl reductase, 4VR A0127_08435 0303eedabd49e4e4747f8bbf53fa0304 394 SUPERFAMILY SSF111126 252 389 1.57E-18 T 23-10-2018 IPR024096 NO signalling/Golgi transport ligand-binding domain superfamily A0127_08435 0303eedabd49e4e4747f8bbf53fa0304 394 SMART SM00989 330 392 4.1E-14 T 23-10-2018 IPR004096 4-vinyl reductase, 4VR A0127_08435 0303eedabd49e4e4747f8bbf53fa0304 394 Pfam PF06745 KaiC 3 166 1.1E-12 T 23-10-2018 IPR014774 KaiC-like domain A0127_08435 0303eedabd49e4e4747f8bbf53fa0304 394 Gene3D G3DSA:3.40.50.300 3 227 8.9E-18 T 23-10-2018 A0127_01130 dd7bf091f79b1b3c789e10820eba1ee1 144 Pfam PF03684 Uncharacterised protein family (UPF0179) 4 139 1.1E-42 T 23-10-2018 IPR005369 Uncharacterised protein family UPF0179 A0127_01130 dd7bf091f79b1b3c789e10820eba1ee1 144 Hamap MF_00498 UPF0179 protein . 2 141 23.271 T 23-10-2018 IPR005369 Uncharacterised protein family UPF0179 A0127_01130 dd7bf091f79b1b3c789e10820eba1ee1 144 PIRSF PIRSF006595 1 144 2.2E-51 T 23-10-2018 IPR005369 Uncharacterised protein family UPF0179 A0127_01130 dd7bf091f79b1b3c789e10820eba1ee1 144 ProDom PD016182 UPF0179 TK0790 TV1250 PAE0681 PF1381 AF2154 MA3685 VNG1401C MJ1627 PH1477 3 143 3.0E-75 T 23-10-2018 IPR005369 Uncharacterised protein family UPF0179 A0127_03820 96134b92e8dcd7a2a0dd6a976ca2d41f 142 Pfam PF13380 CoA binding domain 23 137 9.1E-41 T 23-10-2018 IPR003781 CoA-binding GO:0048037 A0127_03820 96134b92e8dcd7a2a0dd6a976ca2d41f 142 SUPERFAMILY SSF51735 7 139 7.35E-46 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A0127_03820 96134b92e8dcd7a2a0dd6a976ca2d41f 142 SMART SM00881 18 111 1.3E-30 T 23-10-2018 IPR003781 CoA-binding GO:0048037 A0127_03820 96134b92e8dcd7a2a0dd6a976ca2d41f 142 Gene3D G3DSA:3.40.50.720 4 142 3.5E-51 T 23-10-2018 A0127_01880 47a39a80b4bcda9d57a479494788a390 832 SMART SM00490 453 538 6.6E-20 T 23-10-2018 IPR001650 Helicase, C-terminal A0127_01880 47a39a80b4bcda9d57a479494788a390 832 Gene3D G3DSA:3.40.50.300 403 612 1.6E-29 T 23-10-2018 A0127_01880 47a39a80b4bcda9d57a479494788a390 832 SUPERFAMILY SSF52540 227 552 1.26E-50 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_01880 47a39a80b4bcda9d57a479494788a390 832 Pfam PF00270 DEAD/DEAH box helicase 219 382 2.4E-25 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A0127_01880 47a39a80b4bcda9d57a479494788a390 832 SMART SM00487 213 410 9.5E-31 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A0127_01880 47a39a80b4bcda9d57a479494788a390 832 Pfam PF00271 Helicase conserved C-terminal domain 418 536 9.7E-14 T 23-10-2018 IPR001650 Helicase, C-terminal A0127_01880 47a39a80b4bcda9d57a479494788a390 832 Gene3D G3DSA:3.40.50.300 200 402 3.3E-51 T 23-10-2018 A0127_02445 4c36e0bec634b466fd3276c7a9b0354f 237 Gene3D G3DSA:3.40.50.12500 6 237 2.1E-88 T 23-10-2018 A0127_02445 4c36e0bec634b466fd3276c7a9b0354f 237 Pfam PF01177 Asp/Glu/Hydantoin racemase 9 215 2.6E-13 T 23-10-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 A0127_02445 4c36e0bec634b466fd3276c7a9b0354f 237 PIRSF PIRSF015736 1 237 5.5E-92 T 23-10-2018 IPR026286 Maleate isomerase/Arylmalonate decarboxylase A0127_06205 3c91c9be171272ef2fa7da5a9ed822dc 281 SUPERFAMILY SSF103481 185 277 9.55E-14 T 23-10-2018 A0127_06205 3c91c9be171272ef2fa7da5a9ed822dc 281 SUPERFAMILY SSF103481 38 139 1.44E-13 T 23-10-2018 A0127_06205 3c91c9be171272ef2fa7da5a9ed822dc 281 Pfam PF00892 EamA-like transporter family 8 137 1.3E-15 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A0127_06205 3c91c9be171272ef2fa7da5a9ed822dc 281 Pfam PF00892 EamA-like transporter family 150 276 6.3E-19 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A0127_02955 e42050df95afd8f587329efecf1a70bc 237 ProSitePatterns PS01057 SAICAR synthetase signature 1. 85 99 - T 23-10-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A0127_02955 e42050df95afd8f587329efecf1a70bc 237 Gene3D G3DSA:3.30.200.20 22 231 3.1E-94 T 23-10-2018 A0127_02955 e42050df95afd8f587329efecf1a70bc 237 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 4 233 32.554 T 23-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A0127_02955 e42050df95afd8f587329efecf1a70bc 237 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 6 214 9.2E-74 T 23-10-2018 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 A0127_02955 e42050df95afd8f587329efecf1a70bc 237 SUPERFAMILY SSF56104 7 234 1.41E-79 T 23-10-2018 A0127_02955 e42050df95afd8f587329efecf1a70bc 237 Gene3D G3DSA:3.30.470.20 84 219 3.1E-94 T 23-10-2018 A0127_02955 e42050df95afd8f587329efecf1a70bc 237 ProSitePatterns PS01058 SAICAR synthetase signature 2. 171 179 - T 23-10-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A0127_02955 e42050df95afd8f587329efecf1a70bc 237 Pfam PF01259 SAICAR synthetase 7 227 1.0E-65 T 23-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 A0127_07010 f1e5b6d7fd89340298487f379e88ade7 155 Gene3D G3DSA:3.30.428.10 1 139 5.5E-40 T 23-10-2018 IPR036265 HIT-like superfamily A0127_07010 f1e5b6d7fd89340298487f379e88ade7 155 SUPERFAMILY SSF54197 1 126 1.53E-39 T 23-10-2018 IPR036265 HIT-like superfamily A0127_07010 f1e5b6d7fd89340298487f379e88ade7 155 Pfam PF01230 HIT domain 11 100 9.6E-24 T 23-10-2018 IPR001310 Histidine triad (HIT) protein A0127_07010 f1e5b6d7fd89340298487f379e88ade7 155 ProSitePatterns PS00892 HIT domain signature. 81 99 - T 23-10-2018 IPR019808 Histidine triad, conserved site A0127_08135 b937492c19d6b8ba0259998f3d1f9b1a 290 Gene3D G3DSA:3.40.50.1820 45 290 2.7E-44 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold A0127_08135 b937492c19d6b8ba0259998f3d1f9b1a 290 SUPERFAMILY SSF53474 9 290 2.61E-53 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold A0127_08135 b937492c19d6b8ba0259998f3d1f9b1a 290 Pfam PF01738 Dienelactone hydrolase family 209 262 9.8E-5 T 23-10-2018 IPR002925 Dienelactone hydrolase GO:0016787 A0127_08135 b937492c19d6b8ba0259998f3d1f9b1a 290 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 89 182 6.8E-14 T 23-10-2018 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 A0127_07280 a685bed38c778e5ad7e2729e153c8743 248 SUPERFAMILY SSF52540 2 236 6.81E-49 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_07280 a685bed38c778e5ad7e2729e153c8743 248 PRINTS PR01874 DNA repair protein radA signature 14 42 5.1E-10 T 23-10-2018 A0127_07280 a685bed38c778e5ad7e2729e153c8743 248 PRINTS PR01874 DNA repair protein radA signature 135 159 5.1E-10 T 23-10-2018 A0127_07280 a685bed38c778e5ad7e2729e153c8743 248 PRINTS PR01874 DNA repair protein radA signature 56 73 5.1E-10 T 23-10-2018 A0127_07280 a685bed38c778e5ad7e2729e153c8743 248 Gene3D G3DSA:3.40.50.300 1 247 3.5E-81 T 23-10-2018 A0127_07280 a685bed38c778e5ad7e2729e153c8743 248 TIGRFAM TIGR03877 thermo_KaiC_1: KaiC domain protein, Ph0284 family 2 238 1.4E-142 T 23-10-2018 IPR022475 Uncharacterised protein family UPF0273, KaiC-like A0127_07280 a685bed38c778e5ad7e2729e153c8743 248 Hamap MF_01076 UPF0273 protein . 2 245 63.582 T 23-10-2018 IPR022475 Uncharacterised protein family UPF0273, KaiC-like A0127_07280 a685bed38c778e5ad7e2729e153c8743 248 Pfam PF06745 KaiC 5 237 3.7E-92 T 23-10-2018 IPR014774 KaiC-like domain A0127_03105 e3869d501cefc36747c04a045fd034d9 198 Pfam PF02676 Methyltransferase TYW3 11 193 3.4E-46 T 23-10-2018 IPR003827 tRNA wybutosine-synthesizing protein MetaCyc: PWY-7286|Reactome: R-HSA-6782861 A0127_03105 e3869d501cefc36747c04a045fd034d9 198 Hamap MF_00266 tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase [taw3]. 9 195 31.015 T 23-10-2018 IPR022908 tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase GO:0008175|GO:0030488|GO:0031591 MetaCyc: PWY-7286 A0127_03105 e3869d501cefc36747c04a045fd034d9 198 SUPERFAMILY SSF111278 7 193 5.89E-62 T 23-10-2018 IPR036602 tRNA wybutosine-synthesizing-like superfamily MetaCyc: PWY-7286|Reactome: R-HSA-6782861 A0127_03105 e3869d501cefc36747c04a045fd034d9 198 Gene3D G3DSA:3.30.1960.10 2 197 5.4E-69 T 23-10-2018 IPR036602 tRNA wybutosine-synthesizing-like superfamily MetaCyc: PWY-7286|Reactome: R-HSA-6782861 A0127_04745 d2bdc6643dbca357ab9b626f4fdada70 315 Gene3D G3DSA:3.40.1160.10 1 315 3.9E-136 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily A0127_04745 d2bdc6643dbca357ab9b626f4fdada70 315 Pfam PF00696 Amino acid kinase family 2 296 8.4E-30 T 23-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 A0127_04745 d2bdc6643dbca357ab9b626f4fdada70 315 PRINTS PR01469 Bacterial carbamate kinase signature 77 95 1.2E-67 T 23-10-2018 A0127_04745 d2bdc6643dbca357ab9b626f4fdada70 315 PRINTS PR01469 Bacterial carbamate kinase signature 184 202 1.2E-67 T 23-10-2018 A0127_04745 d2bdc6643dbca357ab9b626f4fdada70 315 PRINTS PR01469 Bacterial carbamate kinase signature 44 63 1.2E-67 T 23-10-2018 A0127_04745 d2bdc6643dbca357ab9b626f4fdada70 315 PRINTS PR01469 Bacterial carbamate kinase signature 112 131 1.2E-67 T 23-10-2018 A0127_04745 d2bdc6643dbca357ab9b626f4fdada70 315 PRINTS PR01469 Bacterial carbamate kinase signature 161 180 1.2E-67 T 23-10-2018 A0127_04745 d2bdc6643dbca357ab9b626f4fdada70 315 PRINTS PR01469 Bacterial carbamate kinase signature 269 284 1.2E-67 T 23-10-2018 A0127_04745 d2bdc6643dbca357ab9b626f4fdada70 315 PRINTS PR01469 Bacterial carbamate kinase signature 214 229 1.2E-67 T 23-10-2018 A0127_04745 d2bdc6643dbca357ab9b626f4fdada70 315 SUPERFAMILY SSF53633 1 313 9.56E-88 T 23-10-2018 IPR036393 Acetylglutamate kinase-like superfamily A0127_04745 d2bdc6643dbca357ab9b626f4fdada70 315 PIRSF PIRSF000723 1 314 1.5E-140 T 23-10-2018 IPR003964 Carbamate kinase GO:0006525|GO:0008804 KEGG: 00220+2.7.2.2|KEGG: 00230+2.7.2.2|KEGG: 00910+2.7.2.2 A0127_04745 d2bdc6643dbca357ab9b626f4fdada70 315 TIGRFAM TIGR00746 arcC: carbamate kinase 2 313 3.8E-145 T 23-10-2018 IPR003964 Carbamate kinase GO:0006525|GO:0008804 KEGG: 00220+2.7.2.2|KEGG: 00230+2.7.2.2|KEGG: 00910+2.7.2.2 A0127_02105 20a8f6c828a6863ca8d1aa478c0c9602 81 Gene3D G3DSA:3.30.310.50 2 81 5.2E-25 T 23-10-2018 A0127_02105 20a8f6c828a6863ca8d1aa478c0c9602 81 Pfam PF09341 Transcription factor Pcc1 9 79 1.7E-16 T 23-10-2018 IPR015419 CTAG/Pcc1 family A0127_08090 a1eba62bfbbf83272015f4f238943d8e 133 Gene3D G3DSA:3.40.1360.10 3 117 2.1E-21 T 23-10-2018 A0127_08090 a1eba62bfbbf83272015f4f238943d8e 133 SMART SM00493 20 90 1.1E-5 T 23-10-2018 IPR006171 TOPRIM domain A0127_08090 a1eba62bfbbf83272015f4f238943d8e 133 Pfam PF01751 Toprim domain 51 86 1.1E-5 T 23-10-2018 IPR006171 TOPRIM domain A0127_08090 a1eba62bfbbf83272015f4f238943d8e 133 Hamap MF_01095 UPF0292 protein . 3 123 31.923 T 23-10-2018 IPR022972 Uncharacterised protein family UPF0292 A0127_08090 a1eba62bfbbf83272015f4f238943d8e 133 SUPERFAMILY SSF110455 19 88 1.03E-5 T 23-10-2018 A0127_02840 2a5366a8e8d3087cc7343e084285cd76 109 Gene3D G3DSA:2.40.50.140 1 109 7.0E-34 T 23-10-2018 A0127_02840 2a5366a8e8d3087cc7343e084285cd76 109 Pfam PF01588 Putative tRNA binding domain 14 107 5.7E-25 T 23-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 A0127_02840 2a5366a8e8d3087cc7343e084285cd76 109 SUPERFAMILY SSF50249 7 108 2.08E-29 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A0127_00675 a75193cf3e830ab803ff90e0d1836fb1 149 Gene3D G3DSA:3.40.50.620 1 149 5.1E-27 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A0127_00675 a75193cf3e830ab803ff90e0d1836fb1 149 Pfam PF00582 Universal stress protein family 2 149 6.2E-20 T 23-10-2018 IPR006016 UspA A0127_00675 a75193cf3e830ab803ff90e0d1836fb1 149 SUPERFAMILY SSF52402 2 149 1.59E-23 T 23-10-2018 A0127_03255 e776d4b93cab42d5c846a9b101db2230 91 SUPERFAMILY SSF54984 9 91 4.05E-21 T 23-10-2018 IPR036219 Translation elongation factor eEF-1beta-like superfamily Reactome: R-HSA-156842 A0127_03255 e776d4b93cab42d5c846a9b101db2230 91 Gene3D G3DSA:3.30.70.60 1 91 1.8E-35 T 23-10-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 A0127_03255 e776d4b93cab42d5c846a9b101db2230 91 TIGRFAM TIGR00489 aEF-1_beta: translation elongation factor aEF-1 beta 7 90 2.5E-21 T 23-10-2018 IPR004542 Translation elongation factor EF1B, beta chain, archaeal GO:0003746|GO:0006414 A0127_03255 e776d4b93cab42d5c846a9b101db2230 91 SMART SM00888 5 91 1.1E-33 T 23-10-2018 IPR014038 Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain GO:0003746|GO:0006414 Reactome: R-HSA-156842 A0127_03255 e776d4b93cab42d5c846a9b101db2230 91 PIRSF PIRSF006521 3 91 6.6E-33 T 23-10-2018 IPR004542 Translation elongation factor EF1B, beta chain, archaeal GO:0003746|GO:0006414 A0127_03255 e776d4b93cab42d5c846a9b101db2230 91 Hamap MF_00043 Elongation factor 1-beta [ef1b]. 1 91 40.824 T 23-10-2018 IPR004542 Translation elongation factor EF1B, beta chain, archaeal GO:0003746|GO:0006414 A0127_03255 e776d4b93cab42d5c846a9b101db2230 91 Pfam PF00736 EF-1 guanine nucleotide exchange domain 9 91 8.5E-21 T 23-10-2018 IPR014038 Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain GO:0003746|GO:0006414 Reactome: R-HSA-156842 A0127_07630 3b606323cb5483176b0b5be5dc521657 338 Pfam PF08068 DKCLD (NUC011) domain 15 63 1.3E-19 T 23-10-2018 IPR012960 Dyskerin-like Reactome: R-HSA-171319|Reactome: R-HSA-6790901 A0127_07630 3b606323cb5483176b0b5be5dc521657 338 SUPERFAMILY SSF88697 249 332 7.18E-23 T 23-10-2018 IPR015947 PUA-like superfamily A0127_07630 3b606323cb5483176b0b5be5dc521657 338 Hamap MF_01081 Probable tRNA pseudouridine synthase B [truB]. 40 325 52.047 T 23-10-2018 IPR026326 Probable tRNA pseudouridine synthase B, archaeal GO:0006396 A0127_07630 3b606323cb5483176b0b5be5dc521657 338 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 181 247 1.5E-23 T 23-10-2018 IPR032819 tRNA pseudouridylate synthase B, C-terminal Reactome: R-HSA-171319|Reactome: R-HSA-6790901 A0127_07630 3b606323cb5483176b0b5be5dc521657 338 SMART SM00359 251 325 2.8E-22 T 23-10-2018 IPR002478 PUA domain GO:0003723 A0127_07630 3b606323cb5483176b0b5be5dc521657 338 SUPERFAMILY SSF55120 18 247 1.15E-77 T 23-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 A0127_07630 3b606323cb5483176b0b5be5dc521657 338 TIGRFAM TIGR00425 CBF5: putative rRNA pseudouridine synthase 18 335 1.8E-139 T 23-10-2018 IPR004802 tRNA pseudouridine synthase B family GO:0006396 Reactome: R-HSA-171319|Reactome: R-HSA-6790901 A0127_07630 3b606323cb5483176b0b5be5dc521657 338 Gene3D G3DSA:2.30.130.70 23 332 2.2E-149 T 23-10-2018 A0127_07630 3b606323cb5483176b0b5be5dc521657 338 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 67 180 7.7E-22 T 23-10-2018 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 A0127_07630 3b606323cb5483176b0b5be5dc521657 338 SMART SM01136 4 63 5.1E-27 T 23-10-2018 IPR012960 Dyskerin-like Reactome: R-HSA-171319|Reactome: R-HSA-6790901 A0127_07630 3b606323cb5483176b0b5be5dc521657 338 Gene3D G3DSA:3.30.2350.10 40 243 2.2E-149 T 23-10-2018 A0127_07630 3b606323cb5483176b0b5be5dc521657 338 Pfam PF01472 PUA domain 251 323 5.8E-20 T 23-10-2018 IPR002478 PUA domain GO:0003723 A0127_07630 3b606323cb5483176b0b5be5dc521657 338 TIGRFAM TIGR00451 unchar_dom_2: uncharacterized domain 2 240 320 2.7E-11 T 23-10-2018 IPR004521 Uncharacterised domain CHP00451 GO:0003723 A0127_07240 db0d872dd0179ecccadb4b3416f3737c 161 PRINTS PR00122 Vacuolar ATP synthase 16kDa subunit signature 106 132 1.2E-6 T 23-10-2018 IPR000245 V-ATPase proteolipid subunit GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A0127_07240 db0d872dd0179ecccadb4b3416f3737c 161 PRINTS PR00122 Vacuolar ATP synthase 16kDa subunit signature 133 156 1.2E-6 T 23-10-2018 IPR000245 V-ATPase proteolipid subunit GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A0127_07240 db0d872dd0179ecccadb4b3416f3737c 161 PRINTS PR00122 Vacuolar ATP synthase 16kDa subunit signature 27 51 1.2E-6 T 23-10-2018 IPR000245 V-ATPase proteolipid subunit GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A0127_07240 db0d872dd0179ecccadb4b3416f3737c 161 Gene3D G3DSA:1.20.120.610 2 157 1.3E-40 T 23-10-2018 A0127_07240 db0d872dd0179ecccadb4b3416f3737c 161 SUPERFAMILY SSF81333 6 69 3.27E-10 T 23-10-2018 IPR035921 F/V-ATP synthase subunit C superfamily A0127_07240 db0d872dd0179ecccadb4b3416f3737c 161 Pfam PF00137 ATP synthase subunit C 9 68 4.7E-13 T 23-10-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 A0127_07240 db0d872dd0179ecccadb4b3416f3737c 161 Pfam PF00137 ATP synthase subunit C 96 154 5.6E-16 T 23-10-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 A0127_07240 db0d872dd0179ecccadb4b3416f3737c 161 SUPERFAMILY SSF81333 88 155 1.12E-13 T 23-10-2018 IPR035921 F/V-ATP synthase subunit C superfamily A0127_00230 93031b5ad5cc7d225acd999d726a5118 327 TIGRFAM TIGR01875 cas_MJ0381: CRISPR-associated autoregulator DevR family 4 246 1.1E-57 T 23-10-2018 IPR010154 CRISPR-associated protein Cas7/Cst2/DevR A0127_00230 93031b5ad5cc7d225acd999d726a5118 327 Pfam PF01905 CRISPR-associated negative auto-regulator DevR/Csa2 12 258 4.0E-18 T 23-10-2018 IPR010154 CRISPR-associated protein Cas7/Cst2/DevR A0127_00230 93031b5ad5cc7d225acd999d726a5118 327 TIGRFAM TIGR02585 cas_Cst2_DevR: CRISPR-associated protein Cas7/Cst2/DevR, subtype I-B/TNEAP 9 319 8.9E-85 T 23-10-2018 IPR013414 CRISPR-associated protein Cas7, subtype I-B/Tneap A0127_02515 0de2593910707e8ac61d25c5b2d3217f 150 Pfam PF13636 RNA-binding PUA-like domain of methyltransferase RsmF 99 146 2.8E-14 T 23-10-2018 IPR027391 rRNA small subunit methyltransferase F, RNA-binding PUA-like domain A0127_02515 0de2593910707e8ac61d25c5b2d3217f 150 Gene3D G3DSA:2.30.130.60 90 148 2.2E-8 T 23-10-2018 A0127_05485 a2defe877bc4dd4327cdc5a507ba42b4 88 SUPERFAMILY SSF54285 2 86 2.99E-25 T 23-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp A0127_05485 a2defe877bc4dd4327cdc5a507ba42b4 88 TIGRFAM TIGR01682 moaD: molybdopterin converting factor, subunit 1 3 88 6.8E-19 T 23-10-2018 A0127_05485 a2defe877bc4dd4327cdc5a507ba42b4 88 TIGRFAM TIGR01687 moaD_arch: MoaD family protein 3 88 1.3E-30 T 23-10-2018 IPR010038 MoaD, archaeal-type A0127_05485 a2defe877bc4dd4327cdc5a507ba42b4 88 Pfam PF02597 ThiS family 5 88 1.1E-23 T 23-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 A0127_05485 a2defe877bc4dd4327cdc5a507ba42b4 88 Gene3D G3DSA:3.10.20.30 1 88 7.6E-31 T 23-10-2018 IPR012675 Beta-grasp domain superfamily A0127_00255 090d7390c7b58aa7d13be6f107f3c26c 570 SUPERFAMILY SSF55681 7 478 3.61E-118 T 23-10-2018 A0127_00255 090d7390c7b58aa7d13be6f107f3c26c 570 Gene3D G3DSA:1.20.1430.20 84 147 1.4E-142 T 23-10-2018 A0127_00255 090d7390c7b58aa7d13be6f107f3c26c 570 Hamap MF_00253_A Glycine--tRNA ligase [glyQS]. 6 568 47.135 T 23-10-2018 IPR022960 Glycine-tRNA ligase, archaeal GO:0004820 KEGG: 00970+6.1.1.14 A0127_00255 090d7390c7b58aa7d13be6f107f3c26c 570 TIGRFAM TIGR00389 glyS_dimeric: glycine--tRNA ligase 8 566 5.9E-220 T 23-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A0127_00255 090d7390c7b58aa7d13be6f107f3c26c 570 Gene3D G3DSA:3.30.930.10 14 458 1.4E-142 T 23-10-2018 A0127_00255 090d7390c7b58aa7d13be6f107f3c26c 570 Gene3D G3DSA:1.10.30.30 363 426 1.4E-142 T 23-10-2018 A0127_00255 090d7390c7b58aa7d13be6f107f3c26c 570 SUPERFAMILY SSF52954 462 567 1.66E-32 T 23-10-2018 A0127_00255 090d7390c7b58aa7d13be6f107f3c26c 570 Pfam PF03129 Anticodon binding domain 475 565 1.0E-23 T 23-10-2018 IPR004154 Anticodon-binding A0127_00255 090d7390c7b58aa7d13be6f107f3c26c 570 Gene3D G3DSA:3.40.50.800 473 570 6.7E-33 T 23-10-2018 IPR036621 Anticodon-binding domain superfamily A0127_00255 090d7390c7b58aa7d13be6f107f3c26c 570 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 158 342 4.1E-11 T 23-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 A0127_00255 090d7390c7b58aa7d13be6f107f3c26c 570 PRINTS PR01043 Glycyl-tRNA synthetase signature 27 41 5.2E-57 T 23-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A0127_00255 090d7390c7b58aa7d13be6f107f3c26c 570 PRINTS PR01043 Glycyl-tRNA synthetase signature 435 447 5.2E-57 T 23-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A0127_00255 090d7390c7b58aa7d13be6f107f3c26c 570 PRINTS PR01043 Glycyl-tRNA synthetase signature 193 210 5.2E-57 T 23-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A0127_00255 090d7390c7b58aa7d13be6f107f3c26c 570 PRINTS PR01043 Glycyl-tRNA synthetase signature 513 532 5.2E-57 T 23-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A0127_00255 090d7390c7b58aa7d13be6f107f3c26c 570 PRINTS PR01043 Glycyl-tRNA synthetase signature 210 220 5.2E-57 T 23-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A0127_00255 090d7390c7b58aa7d13be6f107f3c26c 570 PRINTS PR01043 Glycyl-tRNA synthetase signature 161 178 5.2E-57 T 23-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A0127_00255 090d7390c7b58aa7d13be6f107f3c26c 570 PRINTS PR01043 Glycyl-tRNA synthetase signature 142 154 5.2E-57 T 23-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 A0127_03115 96272a1d783c8adebb66dc511a7cb295 205 Gene3D G3DSA:3.30.700.20 9 192 5.6E-74 T 23-10-2018 IPR027485 AMMECR1, N-terminal A0127_03115 96272a1d783c8adebb66dc511a7cb295 205 TIGRFAM TIGR04335 AmmeMemoSam_A: AmmeMemoRadiSam system protein A 11 190 2.1E-58 T 23-10-2018 IPR027623 AmmeMemoRadiSam system protein A A0127_03115 96272a1d783c8adebb66dc511a7cb295 205 Hamap MF_00645 Protein . 5 188 41.556 T 23-10-2018 IPR023472 Uncharacterised protein family MJ0810 A0127_03115 96272a1d783c8adebb66dc511a7cb295 205 SUPERFAMILY SSF143447 4 203 1.02E-69 T 23-10-2018 IPR036071 AMMECR1 domain superfamily A0127_03115 96272a1d783c8adebb66dc511a7cb295 205 Pfam PF01871 AMMECR1 13 190 1.6E-53 T 23-10-2018 IPR002733 AMMECR1 domain A0127_03115 96272a1d783c8adebb66dc511a7cb295 205 TIGRFAM TIGR00296 TIGR00296: uncharacterized protein, PH0010 family 4 197 4.4E-68 T 23-10-2018 IPR023473 AMMECR1 A0127_03115 96272a1d783c8adebb66dc511a7cb295 205 Gene3D G3DSA:3.30.1490.150 117 190 5.6E-74 T 23-10-2018 A0127_00705 f862572ca802ab579dd005b77255a9b9 363 Gene3D G3DSA:3.30.360.10 118 299 9.7E-132 T 23-10-2018 A0127_00705 f862572ca802ab579dd005b77255a9b9 363 Pfam PF16653 Saccharopine dehydrogenase C-terminal domain 117 349 3.9E-30 T 23-10-2018 IPR032095 Saccharopine dehydrogenase, C-terminal Reactome: R-HSA-71064 A0127_00705 f862572ca802ab579dd005b77255a9b9 363 SUPERFAMILY SSF55347 118 257 6.47E-40 T 23-10-2018 A0127_00705 f862572ca802ab579dd005b77255a9b9 363 Gene3D G3DSA:3.40.50.720 2 349 9.7E-132 T 23-10-2018 A0127_00705 f862572ca802ab579dd005b77255a9b9 363 SUPERFAMILY SSF51735 1 169 1.13E-21 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A0127_00705 f862572ca802ab579dd005b77255a9b9 363 Pfam PF03435 Saccharopine dehydrogenase NADP binding domain 3 113 8.6E-19 T 23-10-2018 IPR005097 Saccharopine dehydrogenase, NADP binding domain GO:0016491|GO:0055114 A0127_06355 8c52cd6430b87e21ddc610fef468fa1c 443 Gene3D G3DSA:3.40.190.10 71 397 2.2E-142 T 23-10-2018 A0127_06355 8c52cd6430b87e21ddc610fef468fa1c 443 SUPERFAMILY SSF53850 65 436 3.16E-95 T 23-10-2018 A0127_06355 8c52cd6430b87e21ddc610fef468fa1c 443 PRINTS PR00181 Maltose binding protein signature 170 189 3.0E-13 T 23-10-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0008643|GO:0015144 A0127_06355 8c52cd6430b87e21ddc610fef468fa1c 443 PRINTS PR00181 Maltose binding protein signature 268 287 3.0E-13 T 23-10-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0008643|GO:0015144 A0127_06355 8c52cd6430b87e21ddc610fef468fa1c 443 PRINTS PR00181 Maltose binding protein signature 108 126 3.0E-13 T 23-10-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0008643|GO:0015144 A0127_06355 8c52cd6430b87e21ddc610fef468fa1c 443 PRINTS PR00181 Maltose binding protein signature 397 416 3.0E-13 T 23-10-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0008643|GO:0015144 A0127_06355 8c52cd6430b87e21ddc610fef468fa1c 443 PRINTS PR00181 Maltose binding protein signature 191 210 3.0E-13 T 23-10-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0008643|GO:0015144 A0127_06355 8c52cd6430b87e21ddc610fef468fa1c 443 PRINTS PR00181 Maltose binding protein signature 338 359 3.0E-13 T 23-10-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0008643|GO:0015144 A0127_06355 8c52cd6430b87e21ddc610fef468fa1c 443 Pfam PF13416 Bacterial extracellular solute-binding protein 86 381 1.4E-53 T 23-10-2018 IPR006059 Bacterial extracellular solute-binding protein A0127_06355 8c52cd6430b87e21ddc610fef468fa1c 443 ProSitePatterns PS01037 Bacterial extracellular solute-binding proteins, family 1 signature. 173 190 - T 23-10-2018 IPR006061 Solute-binding family 1, conserved site GO:0055085 A0127_06355 8c52cd6430b87e21ddc610fef468fa1c 443 Gene3D G3DSA:3.40.190.10 178 412 2.2E-142 T 23-10-2018 A0127_02110 39e27bcde912a48030a94559980c7ec0 381 Pfam PF00999 Sodium/hydrogen exchanger family 10 365 4.8E-29 T 23-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 A0127_02110 39e27bcde912a48030a94559980c7ec0 381 Gene3D G3DSA:1.20.1530.20 4 375 1.9E-44 T 23-10-2018 IPR038770 Sodium/solute symporter superfamily A0127_00745 4a1103ed5eb3cd33ed5be68aa5af6bc0 440 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 289 318 4.7E-24 T 23-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 A0127_00745 4a1103ed5eb3cd33ed5be68aa5af6bc0 440 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 183 212 4.7E-24 T 23-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 A0127_00745 4a1103ed5eb3cd33ed5be68aa5af6bc0 440 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 260 287 4.7E-24 T 23-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 A0127_00745 4a1103ed5eb3cd33ed5be68aa5af6bc0 440 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 337 366 4.7E-24 T 23-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 A0127_00745 4a1103ed5eb3cd33ed5be68aa5af6bc0 440 SUPERFAMILY SSF58104 129 430 7.32E-63 T 23-10-2018 A0127_00745 4a1103ed5eb3cd33ed5be68aa5af6bc0 440 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 220 387 2.5E-43 T 23-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 A0127_00745 4a1103ed5eb3cd33ed5be68aa5af6bc0 440 SMART SM00283 162 420 2.9E-64 T 23-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 A0127_00745 4a1103ed5eb3cd33ed5be68aa5af6bc0 440 Gene3D G3DSA:1.10.287.950 125 434 9.5E-64 T 23-10-2018 A0127_03780 c01a9bbdf3198b67f06fe384da09e904 348 SUPERFAMILY SSF53850 37 343 6.04E-52 T 23-10-2018 A0127_03780 c01a9bbdf3198b67f06fe384da09e904 348 Gene3D G3DSA:3.40.190.10 38 341 1.7E-130 T 23-10-2018 A0127_03780 c01a9bbdf3198b67f06fe384da09e904 348 TIGRFAM TIGR03730 tungstate_WtpA: tungstate ABC transporter binding protein WtpA 37 310 6.9E-123 T 23-10-2018 IPR022498 Tungstate ABC transporter, substrate-binding protein WtpA GO:1901359 A0127_03780 c01a9bbdf3198b67f06fe384da09e904 348 Pfam PF13531 Bacterial extracellular solute-binding protein 39 322 1.8E-33 T 23-10-2018 A0127_03780 c01a9bbdf3198b67f06fe384da09e904 348 Gene3D G3DSA:3.40.190.10 124 292 1.7E-130 T 23-10-2018 A0127_08795 9b74f510bf7538cdf6f5545508548c8a 177 PIRSF PIRSF019239 4 177 4.8E-56 T 23-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 A0127_08795 9b74f510bf7538cdf6f5545508548c8a 177 Pfam PF01899 Na+/H+ ion antiporter subunit 15 173 9.6E-46 T 23-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 A0127_07490 58abf1514d2a950f796aebda0d596905 133 PRINTS PR00975 Ribosomal protein S19 family signature 86 98 1.3E-19 T 23-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_07490 58abf1514d2a950f796aebda0d596905 133 PRINTS PR00975 Ribosomal protein S19 family signature 66 85 1.3E-19 T 23-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_07490 58abf1514d2a950f796aebda0d596905 133 PRINTS PR00975 Ribosomal protein S19 family signature 98 113 1.3E-19 T 23-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_07490 58abf1514d2a950f796aebda0d596905 133 Pfam PF00203 Ribosomal protein S19 35 116 1.3E-36 T 23-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_07490 58abf1514d2a950f796aebda0d596905 133 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 35 117 2.8E-27 T 23-10-2018 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 A0127_07490 58abf1514d2a950f796aebda0d596905 133 PIRSF PIRSF002144 1 133 4.9E-41 T 23-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_07490 58abf1514d2a950f796aebda0d596905 133 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 33 122 25.91 T 23-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_07490 58abf1514d2a950f796aebda0d596905 133 SUPERFAMILY SSF54570 34 117 9.94E-32 T 23-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_07490 58abf1514d2a950f796aebda0d596905 133 TIGRFAM TIGR01025 uS19_arch: ribosomal protein uS19 4 133 9.0E-67 T 23-10-2018 IPR005713 Ribosomal protein S19A/S15e GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_07490 58abf1514d2a950f796aebda0d596905 133 Gene3D G3DSA:3.30.860.20 2 133 8.0E-55 T 23-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_07490 58abf1514d2a950f796aebda0d596905 133 ProSitePatterns PS00323 Ribosomal protein S19 signature. 86 110 - T 23-10-2018 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_08420 e771fa4614b4391c87039690e6359d83 67 SMART SM00746 7 45 6.6E-12 T 23-10-2018 IPR011017 TRASH domain A0127_08420 e771fa4614b4391c87039690e6359d83 67 SUPERFAMILY SSF57716 6 56 6.41E-21 T 23-10-2018 A0127_08420 e771fa4614b4391c87039690e6359d83 67 Pfam PF01246 Ribosomal protein L24e 3 60 2.9E-25 T 23-10-2018 IPR000988 Ribosomal protein L24e-related A0127_08420 e771fa4614b4391c87039690e6359d83 67 ProSitePatterns PS01073 Ribosomal protein L24e signature. 9 26 - T 23-10-2018 IPR023442 Ribosomal protein L24e, conserved site A0127_08420 e771fa4614b4391c87039690e6359d83 67 Hamap MF_00773 50S ribosomal protein L24e [rpl24e]. 2 55 27.306 T 23-10-2018 IPR023438 Ribosomal protein L24e GO:0003735|GO:0005622|GO:0005840|GO:0006412 A0127_08420 e771fa4614b4391c87039690e6359d83 67 Gene3D G3DSA:2.30.170.20 2 66 2.5E-27 T 23-10-2018 IPR038630 Ribosomal protein L24e/L24 superfamily A0127_07215 ee29def26d2ba98a5eb5f0646baece99 463 SUPERFAMILY SSF50615 5 66 9.42E-5 T 23-10-2018 IPR036121 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A0127_07215 ee29def26d2ba98a5eb5f0646baece99 463 Gene3D G3DSA:3.40.50.12240 2 459 7.3E-196 T 23-10-2018 A0127_07215 ee29def26d2ba98a5eb5f0646baece99 463 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 132 350 7.5E-69 T 23-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A0127_07215 ee29def26d2ba98a5eb5f0646baece99 463 PIRSF PIRSF039114 1 463 1.3E-256 T 23-10-2018 IPR022879 V-type ATP synthase regulatory subunit B/beta Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A0127_07215 ee29def26d2ba98a5eb5f0646baece99 463 TIGRFAM TIGR01041 ATP_syn_B_arch: ATP synthase archaeal, B subunit 5 461 3.1E-268 T 23-10-2018 IPR005724 ATPase, A1 complex, beta subunit GO:0015986|GO:0033178|GO:0046933 A0127_07215 ee29def26d2ba98a5eb5f0646baece99 463 SUPERFAMILY SSF52540 79 355 3.54E-89 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_07215 ee29def26d2ba98a5eb5f0646baece99 463 SUPERFAMILY SSF47917 363 420 2.49E-9 T 23-10-2018 A0127_07215 ee29def26d2ba98a5eb5f0646baece99 463 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 9 75 2.8E-13 T 23-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A0127_07215 ee29def26d2ba98a5eb5f0646baece99 463 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 341 350 - T 23-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 A0127_07215 ee29def26d2ba98a5eb5f0646baece99 463 Hamap MF_00310 V-type ATP synthase beta chain [atpB]. 3 459 62.605 T 23-10-2018 IPR022879 V-type ATP synthase regulatory subunit B/beta Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A0127_09935 57513d6b8e4f58a8fe02d27b77f6473e 177 Pfam PF00583 Acetyltransferase (GNAT) family 40 160 8.9E-16 T 23-10-2018 IPR000182 GNAT domain A0127_09935 57513d6b8e4f58a8fe02d27b77f6473e 177 Gene3D G3DSA:3.30.1990.20 145 176 2.9E-9 T 23-10-2018 A0127_09935 57513d6b8e4f58a8fe02d27b77f6473e 177 Gene3D G3DSA:3.40.630.30 2 144 1.6E-64 T 23-10-2018 A0127_09935 57513d6b8e4f58a8fe02d27b77f6473e 177 SUPERFAMILY SSF55729 14 169 4.91E-26 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase A0127_05090 60575f999cde9367b95384c320870842 294 Gene3D G3DSA:3.40.1190.20 1 284 1.5E-62 T 23-10-2018 IPR029056 Ribokinase-like A0127_05090 60575f999cde9367b95384c320870842 294 SUPERFAMILY SSF53613 3 272 3.57E-63 T 23-10-2018 IPR029056 Ribokinase-like A0127_05090 60575f999cde9367b95384c320870842 294 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 226 239 - T 23-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 A0127_05090 60575f999cde9367b95384c320870842 294 Pfam PF00294 pfkB family carbohydrate kinase 5 271 2.5E-44 T 23-10-2018 IPR011611 Carbohydrate kinase PfkB A0127_05090 60575f999cde9367b95384c320870842 294 PRINTS PR00990 Ribokinase signature 34 53 9.1E-9 T 23-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A0127_05090 60575f999cde9367b95384c320870842 294 PRINTS PR00990 Ribokinase signature 165 180 9.1E-9 T 23-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A0127_05090 60575f999cde9367b95384c320870842 294 PRINTS PR00990 Ribokinase signature 197 208 9.1E-9 T 23-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A0127_05090 60575f999cde9367b95384c320870842 294 PRINTS PR00990 Ribokinase signature 7 28 9.1E-9 T 23-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A0127_05090 60575f999cde9367b95384c320870842 294 PRINTS PR00990 Ribokinase signature 104 117 9.1E-9 T 23-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A0127_01325 89fea0b1a80de594a2477184b519e455 153 SUPERFAMILY SSF47113 1 153 1.28E-55 T 23-10-2018 IPR009072 Histone-fold GO:0046982 A0127_01325 89fea0b1a80de594a2477184b519e455 153 Gene3D G3DSA:1.10.20.10 5 153 3.9E-39 T 23-10-2018 IPR009072 Histone-fold GO:0046982 A0127_01325 89fea0b1a80de594a2477184b519e455 153 Pfam PF09123 Domain of unknown function (DUF1931) 11 150 3.3E-48 T 23-10-2018 IPR015207 Protein of unknown function DUF1931 A0127_02865 38928ae4766b616c7e60494dd41ab247 270 Pfam PF00583 Acetyltransferase (GNAT) family 25 97 8.9E-10 T 23-10-2018 IPR000182 GNAT domain A0127_02865 38928ae4766b616c7e60494dd41ab247 270 SUPERFAMILY SSF55729 1 128 1.28E-18 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase A0127_02865 38928ae4766b616c7e60494dd41ab247 270 Gene3D G3DSA:3.40.630.30 1 193 1.1E-25 T 23-10-2018 A0127_07250 eaa79e72491fe71041958c57cf72e06b 103 SUPERFAMILY SSF81573 17 72 2.49E-6 T 23-10-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain superfamily A0127_07250 eaa79e72491fe71041958c57cf72e06b 103 Pfam PF16999 Vacuolar (H+)-ATPase G subunit 6 79 4.2E-7 T 23-10-2018 A0127_07250 eaa79e72491fe71041958c57cf72e06b 103 TIGRFAM TIGR02926 AhaH: ATP synthase archaeal, H subunit 5 89 3.7E-16 T 23-10-2018 IPR014275 ATPase, A1A0, subunit H A0127_06240 3571d73429c0d8e54d57cda5f9135e83 396 Pfam PF10672 S-adenosylmethionine-dependent methyltransferase 169 334 2.5E-20 T 23-10-2018 IPR019614 S-adenosylmethionine-dependent methyltransferase GO:0008168 A0127_06240 3571d73429c0d8e54d57cda5f9135e83 396 Gene3D G3DSA:3.40.50.150 179 396 5.0E-71 T 23-10-2018 A0127_06240 3571d73429c0d8e54d57cda5f9135e83 396 Gene3D G3DSA:3.30.750.80 72 178 4.3E-37 T 23-10-2018 A0127_06240 3571d73429c0d8e54d57cda5f9135e83 396 Gene3D G3DSA:2.30.130.10 1 70 2.2E-21 T 23-10-2018 IPR036974 PUA domain superfamily GO:0003723 A0127_06240 3571d73429c0d8e54d57cda5f9135e83 396 SUPERFAMILY SSF53335 78 389 5.77E-68 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A0127_06240 3571d73429c0d8e54d57cda5f9135e83 396 SUPERFAMILY SSF88697 1 69 8.95E-17 T 23-10-2018 IPR015947 PUA-like superfamily A0127_06240 3571d73429c0d8e54d57cda5f9135e83 396 SMART SM00359 2 87 6.5E-22 T 23-10-2018 IPR002478 PUA domain GO:0003723 A0127_06240 3571d73429c0d8e54d57cda5f9135e83 396 Pfam PF01472 PUA domain 3 75 5.2E-14 T 23-10-2018 IPR002478 PUA domain GO:0003723 A0127_03165 fd12b1592749ab9c18e3e2e549866ecf 334 SMART SM00382 27 210 5.8E-17 T 23-10-2018 IPR003593 AAA+ ATPase domain A0127_03165 fd12b1592749ab9c18e3e2e549866ecf 334 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A0127_03165 fd12b1592749ab9c18e3e2e549866ecf 334 SUPERFAMILY SSF52540 4 241 1.65E-88 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_03165 fd12b1592749ab9c18e3e2e549866ecf 334 Pfam PF00005 ABC transporter 22 160 1.5E-36 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A0127_03165 fd12b1592749ab9c18e3e2e549866ecf 334 Gene3D G3DSA:3.40.50.300 1 236 7.5E-76 T 23-10-2018 A0127_01710 6955d81e87e6e74a5942640529c0f662 171 Pfam PF02915 Rubrerythrin 10 124 2.9E-24 T 23-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 A0127_01710 6955d81e87e6e74a5942640529c0f662 171 SUPERFAMILY SSF57802 137 170 2.19E-10 T 23-10-2018 A0127_01710 6955d81e87e6e74a5942640529c0f662 171 SUPERFAMILY SSF47240 3 132 2.64E-37 T 23-10-2018 IPR009078 Ferritin-like superfamily A0127_01710 6955d81e87e6e74a5942640529c0f662 171 Gene3D G3DSA:1.20.1260.10 2 132 1.4E-46 T 23-10-2018 IPR012347 Ferritin-like A0127_01710 6955d81e87e6e74a5942640529c0f662 171 Gene3D G3DSA:2.20.28.10 133 171 5.2E-17 T 23-10-2018 A0127_03185 0a78f08a5286561a40b92b9095f1a3da 92 Pfam PF08967 Domain of unknown function (DUF1884) 2 91 6.6E-41 T 23-10-2018 IPR014418 Uncharacterised conserved protein UCP004604 A0127_03185 0a78f08a5286561a40b92b9095f1a3da 92 PIRSF PIRSF004604 1 92 2.0E-21 T 23-10-2018 IPR014418 Uncharacterised conserved protein UCP004604 A0127_03185 0a78f08a5286561a40b92b9095f1a3da 92 SUPERFAMILY SSF111057 1 90 1.83E-33 T 23-10-2018 IPR036216 Hypothetical protein UCP004604 superfamily A0127_03185 0a78f08a5286561a40b92b9095f1a3da 92 Gene3D G3DSA:3.30.2320.10 1 92 3.2E-26 T 23-10-2018 A0127_03185 0a78f08a5286561a40b92b9095f1a3da 92 ProDom PD029791 ORF 3'REGION GAP PF1875 PF0899 PH1831 B PHS036 2 91 3.0E-35 T 23-10-2018 IPR014418 Uncharacterised conserved protein UCP004604 A0127_02730 69db7ae1e2b5cd11f5d63a42aa800639 406 Gene3D G3DSA:3.40.50.300 214 401 1.1E-52 T 23-10-2018 A0127_02730 69db7ae1e2b5cd11f5d63a42aa800639 406 Pfam PF00271 Helicase conserved C-terminal domain 229 336 5.3E-30 T 23-10-2018 IPR001650 Helicase, C-terminal A0127_02730 69db7ae1e2b5cd11f5d63a42aa800639 406 SMART SM00487 20 218 6.8E-65 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A0127_02730 69db7ae1e2b5cd11f5d63a42aa800639 406 SMART SM00490 255 336 2.8E-35 T 23-10-2018 IPR001650 Helicase, C-terminal A0127_02730 69db7ae1e2b5cd11f5d63a42aa800639 406 SUPERFAMILY SSF52540 70 357 1.68E-77 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_02730 69db7ae1e2b5cd11f5d63a42aa800639 406 Pfam PF00270 DEAD/DEAH box helicase 25 189 1.1E-48 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A0127_02730 69db7ae1e2b5cd11f5d63a42aa800639 406 Gene3D G3DSA:3.40.50.300 1 207 2.2E-76 T 23-10-2018 A0127_02730 69db7ae1e2b5cd11f5d63a42aa800639 406 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 149 157 - T 23-10-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site A0127_02695 57b51f551361c866238112ded3b6b17a 240 Gene3D G3DSA:3.60.15.10 8 236 6.5E-49 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A0127_02695 57b51f551361c866238112ded3b6b17a 240 Pfam PF00753 Metallo-beta-lactamase superfamily 31 221 4.3E-23 T 23-10-2018 IPR001279 Metallo-beta-lactamase A0127_02695 57b51f551361c866238112ded3b6b17a 240 SUPERFAMILY SSF56281 16 239 2.49E-48 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A0127_02695 57b51f551361c866238112ded3b6b17a 240 SMART SM00849 31 221 1.5E-37 T 23-10-2018 IPR001279 Metallo-beta-lactamase A0127_08055 7176dc2cb5fa36233c099f8c380d7e96 216 Gene3D G3DSA:3.40.50.790 59 150 1.0E-77 T 23-10-2018 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich A0127_08055 7176dc2cb5fa36233c099f8c380d7e96 216 ProSitePatterns PS01199 Ribosomal protein L1 signature. 114 133 - T 23-10-2018 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_08055 7176dc2cb5fa36233c099f8c380d7e96 216 Gene3D G3DSA:3.30.190.20 13 213 1.0E-77 T 23-10-2018 A0127_08055 7176dc2cb5fa36233c099f8c380d7e96 216 Pfam PF00687 Ribosomal protein L1p/L10e family 21 210 2.9E-50 T 23-10-2018 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein A0127_08055 7176dc2cb5fa36233c099f8c380d7e96 216 Hamap MF_01318_A 50S ribosomal protein L1 [rplA]. 4 215 37.372 T 23-10-2018 IPR023669 Ribosomal protein L1, archaea GO:0003723|GO:0003735|GO:0006412|GO:0015934 A0127_08055 7176dc2cb5fa36233c099f8c380d7e96 216 PIRSF PIRSF002155 2 216 3.7E-68 T 23-10-2018 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_08055 7176dc2cb5fa36233c099f8c380d7e96 216 SUPERFAMILY SSF56808 5 214 7.72E-67 T 23-10-2018 IPR023674 Ribosomal protein L1-like A0127_05295 b7d6a5214282242a0034846fbbe9086b 167 Pfam PF01899 Na+/H+ ion antiporter subunit 7 164 4.7E-44 T 23-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 A0127_05295 b7d6a5214282242a0034846fbbe9086b 167 PIRSF PIRSF019239 1 165 3.8E-41 T 23-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 A0127_08585 6870751abf436759060bfed626f75a2c 69 Gene3D G3DSA:2.30.30.240 3 69 1.5E-6 T 23-10-2018 A0127_08585 6870751abf436759060bfed626f75a2c 69 SUPERFAMILY SSF50346 1 66 1.1E-13 T 23-10-2018 IPR011033 PRC-barrel-like superfamily A0127_08585 6870751abf436759060bfed626f75a2c 69 Pfam PF05239 PRC-barrel domain 2 68 1.2E-12 T 23-10-2018 IPR027275 PRC-barrel domain A0127_04290 34de3413939642fc3d4da52eb1ac1819 166 Gene3D G3DSA:3.40.630.30 16 164 2.9E-50 T 23-10-2018 A0127_04290 34de3413939642fc3d4da52eb1ac1819 166 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 26 156 9.7E-37 T 23-10-2018 IPR006464 N-acetyltransferase RimI/Ard1 GO:0006474|GO:0016407 A0127_04290 34de3413939642fc3d4da52eb1ac1819 166 Pfam PF00583 Acetyltransferase (GNAT) family 28 137 1.2E-28 T 23-10-2018 IPR000182 GNAT domain A0127_04290 34de3413939642fc3d4da52eb1ac1819 166 SUPERFAMILY SSF55729 16 158 2.1E-40 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase A0127_02115 3eb7579434d3c8c90d3d05fbe85eae59 135 SUPERFAMILY SSF55021 57 130 1.07E-11 T 23-10-2018 A0127_02115 3eb7579434d3c8c90d3d05fbe85eae59 135 Pfam PF01842 ACT domain 59 120 9.3E-11 T 23-10-2018 IPR002912 ACT domain A0127_02115 3eb7579434d3c8c90d3d05fbe85eae59 135 Gene3D G3DSA:3.30.70.260 47 131 3.9E-10 T 23-10-2018 A0127_04345 c497ae5ba74d371f90541ec446bb8f59 448 Gene3D G3DSA:3.40.50.720 3 132 1.0E-8 T 23-10-2018 A0127_04345 c497ae5ba74d371f90541ec446bb8f59 448 Gene3D G3DSA:3.40.50.300 211 306 1.1E-8 T 23-10-2018 A0127_04345 c497ae5ba74d371f90541ec446bb8f59 448 SUPERFAMILY SSF52540 125 299 1.61E-12 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_04345 c497ae5ba74d371f90541ec446bb8f59 448 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 241 299 1.4E-5 T 23-10-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain A0127_03300 f14fb3bc12aad5e896a746956562328f 387 Pfam PF01266 FAD dependent oxidoreductase 9 356 3.2E-73 T 23-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 A0127_03300 f14fb3bc12aad5e896a746956562328f 387 Gene3D G3DSA:3.50.50.60 10 361 2.9E-135 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A0127_03300 f14fb3bc12aad5e896a746956562328f 387 SUPERFAMILY SSF51905 8 378 2.07E-60 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A0127_03300 f14fb3bc12aad5e896a746956562328f 387 Gene3D G3DSA:3.30.9.10 88 316 2.9E-135 T 23-10-2018 A0127_03300 f14fb3bc12aad5e896a746956562328f 387 SUPERFAMILY SSF54373 224 317 5.62E-8 T 23-10-2018 A0127_08995 081756f9f276a8d13fb80c7a17247fbb 257 Pfam PF02673 Bacitracin resistance protein BacA 8 248 5.0E-24 T 23-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 A0127_07060 435c196cdec81f8e038c6e91292416d3 174 SUPERFAMILY SSF88697 3 145 8.12E-17 T 23-10-2018 IPR015947 PUA-like superfamily A0127_07060 435c196cdec81f8e038c6e91292416d3 174 Pfam PF04266 ASCH domain 6 108 5.2E-7 T 23-10-2018 IPR007374 ASCH domain A0127_07060 435c196cdec81f8e038c6e91292416d3 174 SMART SM01022 5 125 2.4E-6 T 23-10-2018 IPR007374 ASCH domain A0127_04165 6657db4d13fa71eb15536543185b5450 228 SUPERFAMILY SSF53335 5 225 5.02E-41 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A0127_04165 6657db4d13fa71eb15536543185b5450 228 Pfam PF13649 Methyltransferase domain 42 136 1.0E-26 T 23-10-2018 A0127_04165 6657db4d13fa71eb15536543185b5450 228 Gene3D G3DSA:3.40.50.150 1 227 1.4E-69 T 23-10-2018 A0127_07180 ae94a1d9006112dedffcadc5e998297b 233 Gene3D G3DSA:3.40.50.11570 16 217 1.9E-45 T 23-10-2018 A0127_07180 ae94a1d9006112dedffcadc5e998297b 233 Pfam PF03192 Pyrococcus protein of unknown function, DUF257 19 215 4.0E-63 T 23-10-2018 IPR005489 Protein of unknown function DUF257 A0127_07020 e3f8fe7c58d2121a98e2eaab8a08ce6f 260 Hamap MF_00289_A Proteasome subunit alpha [prcA]. 5 234 47.673 T 23-10-2018 IPR019982 Proteasome alpha subunit, archaeal GO:0004298|GO:0005839|GO:0051603 A0127_07020 e3f8fe7c58d2121a98e2eaab8a08ce6f 260 Pfam PF10584 Proteasome subunit A N-terminal signature 10 32 4.0E-12 T 23-10-2018 IPR000426 Proteasome alpha-subunit, N-terminal domain GO:0004175|GO:0006511|GO:0019773 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 A0127_07020 e3f8fe7c58d2121a98e2eaab8a08ce6f 260 ProSitePatterns PS00388 Proteasome alpha-type subunits signature. 10 32 - T 23-10-2018 IPR000426 Proteasome alpha-subunit, N-terminal domain GO:0004175|GO:0006511|GO:0019773 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 A0127_07020 e3f8fe7c58d2121a98e2eaab8a08ce6f 260 Pfam PF00227 Proteasome subunit 33 215 7.8E-64 T 23-10-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 A0127_07020 e3f8fe7c58d2121a98e2eaab8a08ce6f 260 SMART SM00948 10 32 3.4E-10 T 23-10-2018 IPR000426 Proteasome alpha-subunit, N-terminal domain GO:0004175|GO:0006511|GO:0019773 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 A0127_07020 e3f8fe7c58d2121a98e2eaab8a08ce6f 260 TIGRFAM TIGR03633 arc_protsome_A: proteasome endopeptidase complex, archaeal, alpha subunit 8 234 1.2E-105 T 23-10-2018 IPR019982 Proteasome alpha subunit, archaeal GO:0004298|GO:0005839|GO:0051603 A0127_07020 e3f8fe7c58d2121a98e2eaab8a08ce6f 260 Gene3D G3DSA:3.60.20.10 5 253 2.6E-90 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A0127_07020 e3f8fe7c58d2121a98e2eaab8a08ce6f 260 SUPERFAMILY SSF56235 7 241 8.55E-82 T 23-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal A0127_09480 f680ee22eaed30c2579a30728a260100 599 Pfam PF00374 Nickel-dependent hydrogenase 247 316 2.8E-12 T 23-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 A0127_09480 f680ee22eaed30c2579a30728a260100 599 ProSitePatterns PS00542 Respiratory chain NADH dehydrogenase 30 Kd subunit signature. 150 171 - T 23-10-2018 IPR020396 NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A0127_09480 f680ee22eaed30c2579a30728a260100 599 SUPERFAMILY SSF56762 219 569 1.96E-115 T 23-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A0127_09480 f680ee22eaed30c2579a30728a260100 599 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 63 190 5.6E-22 T 23-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A0127_09480 f680ee22eaed30c2579a30728a260100 599 SUPERFAMILY SSF143243 39 223 1.44E-39 T 23-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A0127_09480 f680ee22eaed30c2579a30728a260100 599 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 120 170 3.0E-16 T 23-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A0127_09480 f680ee22eaed30c2579a30728a260100 599 Gene3D G3DSA:1.10.645.20 209 569 1.7E-128 T 23-10-2018 IPR038290 NADH-quinone oxidoreductase, subunit D superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A0127_09480 f680ee22eaed30c2579a30728a260100 599 Gene3D G3DSA:3.30.460.80 16 169 1.5E-14 T 23-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A0127_09480 f680ee22eaed30c2579a30728a260100 599 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 500 569 5.4E-16 T 23-10-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A0127_09480 f680ee22eaed30c2579a30728a260100 599 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 324 490 1.5E-43 T 23-10-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A0127_05375 24b5ebc0abae6f8005cd65d67b446747 160 SUPERFAMILY SSF143437 37 148 3.84E-17 T 23-10-2018 A0127_05375 24b5ebc0abae6f8005cd65d67b446747 160 Pfam PF02926 THUMP domain 33 148 9.3E-21 T 23-10-2018 IPR004114 THUMP domain GO:0003723 A0127_05375 24b5ebc0abae6f8005cd65d67b446747 160 Gene3D G3DSA:3.30.2130.30 1 151 2.4E-17 T 23-10-2018 A0127_05375 24b5ebc0abae6f8005cd65d67b446747 160 SMART SM00981 62 149 1.5E-16 T 23-10-2018 IPR004114 THUMP domain GO:0003723 A0127_00150 d84ae8f001389798027ff2d69292ea10 331 SUPERFAMILY SSF52540 10 322 3.2E-44 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_00150 d84ae8f001389798027ff2d69292ea10 331 Pfam PF02374 Anion-transporting ATPase 12 327 6.7E-74 T 23-10-2018 IPR025723 Anion-transporting ATPase-like domain Reactome: R-HSA-381038 A0127_00150 d84ae8f001389798027ff2d69292ea10 331 Gene3D G3DSA:3.40.50.300 4 331 5.6E-88 T 23-10-2018 A0127_00150 d84ae8f001389798027ff2d69292ea10 331 TIGRFAM TIGR00345 GET3_arsA_TRC40: transport-energizing ATPase, TRC40/GET3/ArsA family 15 323 2.5E-75 T 23-10-2018 IPR016300 Arsenical pump ATPase, ArsA/GET3 GO:0005524|GO:0016887 Reactome: R-HSA-381038 A0127_01700 2bd5c0929532d2cde5b9cc923f6ffc08 115 Pfam PF01880 Desulfoferrodoxin 9 111 7.2E-33 T 23-10-2018 IPR002742 Desulfoferrodoxin, ferrous iron-binding domain GO:0005506|GO:0016491|GO:0055114 A0127_01700 2bd5c0929532d2cde5b9cc923f6ffc08 115 SUPERFAMILY SSF49367 1 114 1.7E-40 T 23-10-2018 IPR036073 Desulfoferrodoxin, ferrous iron-binding domain superfamily GO:0005506|GO:0016491|GO:0055114 A0127_01700 2bd5c0929532d2cde5b9cc923f6ffc08 115 TIGRFAM TIGR00332 neela_ferrous: desulfoferrodoxin ferrous iron-binding domain 8 114 1.5E-34 T 23-10-2018 IPR002742 Desulfoferrodoxin, ferrous iron-binding domain GO:0005506|GO:0016491|GO:0055114 A0127_01700 2bd5c0929532d2cde5b9cc923f6ffc08 115 Gene3D G3DSA:2.60.40.730 1 115 4.4E-52 T 23-10-2018 IPR036073 Desulfoferrodoxin, ferrous iron-binding domain superfamily GO:0005506|GO:0016491|GO:0055114 A0127_08285 0ce99b6a485c03d1504f57431bd5d9ae 122 Pfam PF14358 Domain of unknown function (DUF4405) 11 75 8.9E-17 T 23-10-2018 IPR025517 Domain of unknown function DUF4405 A0127_09625 d94b449b03c6415473d6cf2a836d3789 132 Gene3D G3DSA:3.30.70.20 20 125 7.6E-20 T 23-10-2018 A0127_09625 d94b449b03c6415473d6cf2a836d3789 132 Pfam PF13247 4Fe-4S dicluster domain 28 109 1.6E-8 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A0127_09625 d94b449b03c6415473d6cf2a836d3789 132 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 63 74 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A0127_09625 d94b449b03c6415473d6cf2a836d3789 132 SUPERFAMILY SSF54862 16 126 1.32E-28 T 23-10-2018 A0127_06365 138cebb33d100829694335781cf78b24 448 Pfam PF08323 Starch synthase catalytic domain 2 202 2.6E-35 T 23-10-2018 IPR013534 Starch synthase, catalytic domain KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 A0127_06365 138cebb33d100829694335781cf78b24 448 Gene3D G3DSA:3.40.50.2000 218 426 2.1E-109 T 23-10-2018 A0127_06365 138cebb33d100829694335781cf78b24 448 Pfam PF00534 Glycosyl transferases group 1 251 417 3.5E-25 T 23-10-2018 IPR001296 Glycosyl transferase, family 1 A0127_06365 138cebb33d100829694335781cf78b24 448 Gene3D G3DSA:3.40.50.2000 2 436 2.1E-109 T 23-10-2018 A0127_06365 138cebb33d100829694335781cf78b24 448 SUPERFAMILY SSF53756 1 440 4.19E-86 T 23-10-2018 A0127_04505 6336972655ebae0bcfc4e1e7c483895c 110 SUPERFAMILY SSF46785 4 102 1.92E-15 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A0127_04505 6336972655ebae0bcfc4e1e7c483895c 110 Gene3D G3DSA:1.10.10.10 2 109 1.6E-33 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A0127_04505 6336972655ebae0bcfc4e1e7c483895c 110 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 12 83 4.1E-10 T 23-10-2018 IPR002831 Transcription regulator TrmB, N-terminal A0127_07785 e16e267ca05e17aa9e34e6cd73d975cd 267 Pfam PF01048 Phosphorylase superfamily 3 246 9.6E-54 T 23-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 A0127_07785 e16e267ca05e17aa9e34e6cd73d975cd 267 Hamap MF_01963 S-methyl-5'-thioadenosine phosphorylase [mtnP]. 2 266 43.527 T 23-10-2018 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112|Reactome: R-HSA-8950505 A0127_07785 e16e267ca05e17aa9e34e6cd73d975cd 267 Gene3D G3DSA:3.40.50.1580 1 266 5.1E-101 T 23-10-2018 A0127_07785 e16e267ca05e17aa9e34e6cd73d975cd 267 SUPERFAMILY SSF53167 1 264 2.09E-96 T 23-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 A0127_07785 e16e267ca05e17aa9e34e6cd73d975cd 267 TIGRFAM TIGR01694 MTAP: methylthioadenosine phosphorylase 4 247 5.5E-96 T 23-10-2018 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112|Reactome: R-HSA-8950505 A0127_07785 e16e267ca05e17aa9e34e6cd73d975cd 267 ProSitePatterns PS01240 Purine and other phosphorylases family 2 signature. 48 88 - T 23-10-2018 IPR018099 Purine phosphorylase, family 2, conserved site GO:0016763 A0127_03085 796cc06d950e0acbc19f24b52201433f 350 TIGRFAM TIGR00748 HMG_CoA_syn_Arc: putative hydroxymethylglutaryl-CoA synthase 10 349 1.8E-188 T 23-10-2018 IPR004656 Putative condensing enzyme FabH-related A0127_03085 796cc06d950e0acbc19f24b52201433f 350 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 223 303 2.3E-10 T 23-10-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 A0127_03085 796cc06d950e0acbc19f24b52201433f 350 Gene3D G3DSA:3.40.47.10 8 348 4.4E-68 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 A0127_03085 796cc06d950e0acbc19f24b52201433f 350 SUPERFAMILY SSF53901 175 348 3.93E-45 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 A0127_03085 796cc06d950e0acbc19f24b52201433f 350 SUPERFAMILY SSF53901 10 169 3.93E-30 T 23-10-2018 IPR016039 Thiolase-like GO:0003824 A0127_03085 796cc06d950e0acbc19f24b52201433f 350 Hamap MF_01409 UPF0219 protein . 10 350 60.328 T 23-10-2018 IPR004656 Putative condensing enzyme FabH-related A0127_07410 6766c5a1bd68bdc6a5514fbe0ae88d1e 749 Pfam PF10131 6-pyruvoyl-tetrahydropterin synthase related domain; membrane protein 64 624 1.8E-120 T 23-10-2018 IPR018776 Membrane protein, 6-pyruvoyl-tetrahydropterin synthase-related domain A0127_03760 12e930543f5fba3f42f08bdef9681aa3 218 TIGRFAM TIGR00104 tRNA_TsaA: tRNA-Thr(GGU) m(6)t(6)A37 methyltransferase TsaA 21 132 1.5E-35 T 23-10-2018 IPR023370 YaeB-like, N-terminal domain A0127_03760 12e930543f5fba3f42f08bdef9681aa3 218 Pfam PF01980 Uncharacterised protein family UPF0066 21 128 1.2E-29 T 23-10-2018 IPR023370 YaeB-like, N-terminal domain A0127_03760 12e930543f5fba3f42f08bdef9681aa3 218 ProSitePatterns PS01318 TsaA-like domain signature. 76 87 - T 23-10-2018 IPR023368 Uncharacterised protein family UPF0066, conserved site A0127_03760 12e930543f5fba3f42f08bdef9681aa3 218 Gene3D G3DSA:2.40.30.70 8 146 1.9E-31 T 23-10-2018 IPR036414 YaeB, N-terminal domain superfamily A0127_03760 12e930543f5fba3f42f08bdef9681aa3 218 SUPERFAMILY SSF118196 4 141 1.7E-39 T 23-10-2018 IPR036413 YaeB-like superfamily A0127_06880 4257e480e6797d2bb3e345fd82e4dae9 726 Gene3D G3DSA:1.50.10.20 258 356 7.2E-9 T 23-10-2018 A0127_06880 4257e480e6797d2bb3e345fd82e4dae9 726 SUPERFAMILY SSF48239 49 492 1.57E-28 T 23-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid A0127_06880 4257e480e6797d2bb3e345fd82e4dae9 726 ProSitePatterns PS00018 EF-hand calcium-binding domain. 708 720 - T 23-10-2018 IPR018247 EF-Hand 1, calcium-binding site A0127_06880 4257e480e6797d2bb3e345fd82e4dae9 726 Pfam PF00432 Prenyltransferase and squalene oxidase repeat 427 465 3.5 T 23-10-2018 IPR001330 PFTB repeat GO:0003824 A0127_06880 4257e480e6797d2bb3e345fd82e4dae9 726 Pfam PF00432 Prenyltransferase and squalene oxidase repeat 57 93 2.8E-4 T 23-10-2018 IPR001330 PFTB repeat GO:0003824 A0127_06880 4257e480e6797d2bb3e345fd82e4dae9 726 Pfam PF00432 Prenyltransferase and squalene oxidase repeat 288 325 0.0023 T 23-10-2018 IPR001330 PFTB repeat GO:0003824 A0127_06880 4257e480e6797d2bb3e345fd82e4dae9 726 Gene3D G3DSA:1.50.10.20 12 198 4.3E-15 T 23-10-2018 A0127_06880 4257e480e6797d2bb3e345fd82e4dae9 726 Gene3D G3DSA:1.50.10.20 357 499 2.4E-6 T 23-10-2018 A0127_05565 7fbb552a4886a0fb8dc948f73b535f96 325 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 4 291 2.8E-101 T 23-10-2018 IPR017861 Kae1/TsaD family A0127_05565 7fbb552a4886a0fb8dc948f73b535f96 325 TIGRFAM TIGR03722 arch_KAE1: universal archaeal protein Kae1 4 324 2.6E-153 T 23-10-2018 IPR022449 tRNA N6-adenosine threonylcarbamoyltransferase Kae1, archaea GO:0000408|GO:0002949 A0127_05565 7fbb552a4886a0fb8dc948f73b535f96 325 Gene3D G3DSA:3.30.420.40 4 298 5.0E-114 T 23-10-2018 A0127_05565 7fbb552a4886a0fb8dc948f73b535f96 325 Hamap MF_01446 tRNA N6-adenosine threonylcarbamoyltransferase [kae1]. 1 325 38.592 T 23-10-2018 IPR034680 tRNA N6-adenosine threonylcarbamoyltransferase Kae1/OSGEP GO:0000408|GO:0002949 Reactome: R-HSA-6782315 A0127_05565 7fbb552a4886a0fb8dc948f73b535f96 325 Pfam PF00814 Glycoprotease family 23 292 8.8E-96 T 23-10-2018 IPR000905 Gcp-like domain A0127_05565 7fbb552a4886a0fb8dc948f73b535f96 325 ProSitePatterns PS01016 Glycoprotease family signature. 92 112 - T 23-10-2018 IPR017860 Peptidase M22, conserved site Reactome: R-HSA-6782315 A0127_05565 7fbb552a4886a0fb8dc948f73b535f96 325 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 124 136 7.2E-42 T 23-10-2018 IPR017861 Kae1/TsaD family A0127_05565 7fbb552a4886a0fb8dc948f73b535f96 325 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 93 112 7.2E-42 T 23-10-2018 IPR017861 Kae1/TsaD family A0127_05565 7fbb552a4886a0fb8dc948f73b535f96 325 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 146 167 7.2E-42 T 23-10-2018 IPR017861 Kae1/TsaD family A0127_05565 7fbb552a4886a0fb8dc948f73b535f96 325 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 4 17 7.2E-42 T 23-10-2018 IPR017861 Kae1/TsaD family A0127_05565 7fbb552a4886a0fb8dc948f73b535f96 325 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 72 92 7.2E-42 T 23-10-2018 IPR017861 Kae1/TsaD family A0127_05565 7fbb552a4886a0fb8dc948f73b535f96 325 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 248 257 7.2E-42 T 23-10-2018 IPR017861 Kae1/TsaD family A0127_05565 7fbb552a4886a0fb8dc948f73b535f96 325 SUPERFAMILY SSF53067 1 293 1.86E-36 T 23-10-2018 A0127_05565 7fbb552a4886a0fb8dc948f73b535f96 325 Gene3D G3DSA:3.30.420.40 122 278 5.0E-114 T 23-10-2018 A0127_06630 d0828856198b533a0622b2634ce88a3b 384 Pfam PF00534 Glycosyl transferases group 1 196 356 7.6E-32 T 23-10-2018 IPR001296 Glycosyl transferase, family 1 A0127_06630 d0828856198b533a0622b2634ce88a3b 384 SUPERFAMILY SSF53756 12 378 1.53E-66 T 23-10-2018 A0127_06630 d0828856198b533a0622b2634ce88a3b 384 Pfam PF13439 Glycosyltransferase Family 4 77 186 1.8E-10 T 23-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 A0127_06630 d0828856198b533a0622b2634ce88a3b 384 Gene3D G3DSA:3.40.50.2000 183 362 1.6E-53 T 23-10-2018 A0127_06630 d0828856198b533a0622b2634ce88a3b 384 Gene3D G3DSA:3.40.50.2000 38 370 1.6E-53 T 23-10-2018 A0127_07115 d1b6f01775301ac822c7c932fb398f88 170 ProSitePatterns PS01269 Uncharacterized protein family UPF0025 signature. 108 132 - T 23-10-2018 IPR020935 Phosphodiesterase YfcE, conserved site A0127_07115 d1b6f01775301ac822c7c932fb398f88 170 Gene3D G3DSA:3.60.21.10 1 159 1.8E-51 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like A0127_07115 d1b6f01775301ac822c7c932fb398f88 170 TIGRFAM TIGR00040 yfcE: phosphodiesterase, MJ0936 family 1 155 8.2E-39 T 23-10-2018 IPR000979 Phosphodiesterase MJ0936/Vps29 Reactome: R-HSA-3238698 A0127_07115 d1b6f01775301ac822c7c932fb398f88 170 SUPERFAMILY SSF56300 1 160 3.38E-39 T 23-10-2018 A0127_07115 d1b6f01775301ac822c7c932fb398f88 170 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 1 151 1.5E-32 T 23-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 A0127_03280 d972e9c5c87b10f2fa57932818346c99 386 Gene3D G3DSA:3.50.50.60 12 359 2.2E-140 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A0127_03280 d972e9c5c87b10f2fa57932818346c99 386 SUPERFAMILY SSF51905 11 376 3.3E-59 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A0127_03280 d972e9c5c87b10f2fa57932818346c99 386 SUPERFAMILY SSF54373 224 316 7.06E-10 T 23-10-2018 A0127_03280 d972e9c5c87b10f2fa57932818346c99 386 Pfam PF01266 FAD dependent oxidoreductase 12 355 3.6E-73 T 23-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 A0127_03280 d972e9c5c87b10f2fa57932818346c99 386 Gene3D G3DSA:3.30.9.10 88 315 2.2E-140 T 23-10-2018 A0127_03375 339b41b9a2fb60a278504fd3b16a6928 224 SUPERFAMILY SSF56281 1 220 9.04E-40 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A0127_03375 339b41b9a2fb60a278504fd3b16a6928 224 Pfam PF13483 Beta-lactamase superfamily domain 3 189 1.0E-32 T 23-10-2018 A0127_03375 339b41b9a2fb60a278504fd3b16a6928 224 Gene3D G3DSA:3.60.15.10 2 224 1.1E-72 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A0127_03375 339b41b9a2fb60a278504fd3b16a6928 224 SMART SM00849 8 189 5.4E-18 T 23-10-2018 IPR001279 Metallo-beta-lactamase A0127_03375 339b41b9a2fb60a278504fd3b16a6928 224 Hamap MF_00457 UPF0173 metal-dependent hydrolase . 2 224 38.947 T 23-10-2018 IPR022877 Protein of unknown funcion UPF0173 A0127_02160 dc0f5e45eb677e612b62034f4e6b0531 208 Gene3D G3DSA:3.40.50.10480 1 187 1.8E-33 T 23-10-2018 A0127_02160 dc0f5e45eb677e612b62034f4e6b0531 208 Hamap MF_00699 Probable Brix domain-containing ribosomal biogenesis protein. 2 191 29.69 T 23-10-2018 IPR023548 Probable Brix domain-containing ribosomal biogenesis protein A0127_02160 dc0f5e45eb677e612b62034f4e6b0531 208 SMART SM00879 3 190 2.6E-17 T 23-10-2018 IPR007109 Brix domain A0127_02160 dc0f5e45eb677e612b62034f4e6b0531 208 SUPERFAMILY SSF52954 1 193 1.7E-35 T 23-10-2018 A0127_00470 28f7de574f5e6d0842c3b76c2da2b15e 336 SUPERFAMILY SSF53850 39 328 1.6E-75 T 23-10-2018 A0127_00470 28f7de574f5e6d0842c3b76c2da2b15e 336 Pfam PF16868 NMT1-like family 43 327 7.2E-86 T 23-10-2018 IPR011852 TRAP transporter solute receptor, TAXI family A0127_00470 28f7de574f5e6d0842c3b76c2da2b15e 336 Gene3D G3DSA:3.40.190.10 125 262 1.1E-99 T 23-10-2018 A0127_00470 28f7de574f5e6d0842c3b76c2da2b15e 336 TIGRFAM TIGR02122 TRAP_TAXI: TRAP transporter solute receptor, TAXI family 8 327 1.3E-97 T 23-10-2018 IPR011852 TRAP transporter solute receptor, TAXI family A0127_00470 28f7de574f5e6d0842c3b76c2da2b15e 336 Gene3D G3DSA:3.40.190.10 43 327 1.1E-99 T 23-10-2018 A0127_10275 154b012d87cde3af589f7106290dcc38 283 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 156 177 6.9E-29 T 23-10-2018 A0127_10275 154b012d87cde3af589f7106290dcc38 283 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 120 127 6.9E-29 T 23-10-2018 A0127_10275 154b012d87cde3af589f7106290dcc38 283 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 78 92 6.9E-29 T 23-10-2018 A0127_10275 154b012d87cde3af589f7106290dcc38 283 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 242 262 6.9E-29 T 23-10-2018 A0127_10275 154b012d87cde3af589f7106290dcc38 283 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 220 235 6.9E-29 T 23-10-2018 A0127_10275 154b012d87cde3af589f7106290dcc38 283 SUPERFAMILY SSF55424 157 273 6.36E-36 T 23-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 A0127_10275 154b012d87cde3af589f7106290dcc38 283 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 1 140 9.0E-28 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A0127_10275 154b012d87cde3af589f7106290dcc38 283 Gene3D G3DSA:3.30.390.30 159 283 6.9E-40 T 23-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 A0127_10275 154b012d87cde3af589f7106290dcc38 283 SUPERFAMILY SSF51905 30 179 4.2E-24 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A0127_10275 154b012d87cde3af589f7106290dcc38 283 Gene3D G3DSA:3.50.50.60 85 144 1.4E-42 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A0127_10275 154b012d87cde3af589f7106290dcc38 283 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 160 267 2.7E-32 T 23-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 A0127_10275 154b012d87cde3af589f7106290dcc38 283 Gene3D G3DSA:3.50.50.60 1 84 1.4E-42 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A0127_07755 809089609ac2ee48cc06130cfcbc03c6 237 SUPERFAMILY SSF53271 77 236 7.6E-35 T 23-10-2018 IPR029057 Phosphoribosyltransferase-like A0127_07755 809089609ac2ee48cc06130cfcbc03c6 237 Pfam PF00156 Phosphoribosyl transferase domain 97 222 2.9E-13 T 23-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 A0127_07755 809089609ac2ee48cc06130cfcbc03c6 237 Gene3D G3DSA:3.40.50.2020 61 237 3.3E-41 T 23-10-2018 A0127_07755 809089609ac2ee48cc06130cfcbc03c6 237 SUPERFAMILY SSF47413 14 62 5.3E-5 T 23-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A0127_07755 809089609ac2ee48cc06130cfcbc03c6 237 Pfam PF01381 Helix-turn-helix 14 62 3.8E-5 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A0127_03015 e29669bdd9cf594a6d8fc2b969e818dc 331 Gene3D G3DSA:3.30.470.20 87 330 1.2E-99 T 23-10-2018 A0127_03015 e29669bdd9cf594a6d8fc2b969e818dc 331 Pfam PF06849 Protein of unknown function (DUF1246) 3 117 1.3E-33 T 23-10-2018 IPR010672 IMP biosynthesis enzyme PurP, N-terminal GO:0000287|GO:0005524|GO:0006188|GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 A0127_03015 e29669bdd9cf594a6d8fc2b969e818dc 331 SUPERFAMILY SSF52440 1 97 4.41E-31 T 23-10-2018 IPR016185 Pre-ATP-grasp domain superfamily A0127_03015 e29669bdd9cf594a6d8fc2b969e818dc 331 SUPERFAMILY SSF56059 102 331 4.18E-79 T 23-10-2018 A0127_03015 e29669bdd9cf594a6d8fc2b969e818dc 331 Gene3D G3DSA:3.40.50.20 1 85 8.6E-29 T 23-10-2018 A0127_03015 e29669bdd9cf594a6d8fc2b969e818dc 331 Pfam PF06973 Domain of unknown function (DUF1297) 149 331 2.2E-72 T 23-10-2018 IPR009720 IMP biosynthesis enzyme PurP, C-terminal GO:0000287|GO:0005524|GO:0006188|GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 A0127_03015 e29669bdd9cf594a6d8fc2b969e818dc 331 PIRSF PIRSF004602 1 331 4.4E-132 T 23-10-2018 IPR023656 IMP biosynthesis enzyme PurP GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 A0127_03015 e29669bdd9cf594a6d8fc2b969e818dc 331 Gene3D G3DSA:3.30.1490.20 114 174 1.2E-99 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 A0127_03015 e29669bdd9cf594a6d8fc2b969e818dc 331 Hamap MF_01163 5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase [purP]. 1 331 49.482 T 23-10-2018 IPR023656 IMP biosynthesis enzyme PurP GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 A0127_01085 b48c64891bf954f678a62f8f790bbd86 258 SMART SM00090 23 257 3.0E-121 T 23-10-2018 IPR000687 RIO kinase GO:0004674|GO:0005524 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6791226 A0127_01085 b48c64891bf954f678a62f8f790bbd86 258 ProSitePatterns PS01245 RIO1/ZK632.3/MJ0444 family signature. 191 202 - T 23-10-2018 IPR018935 RIO kinase, conserved site GO:0004674|GO:0005524 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6791226 A0127_01085 b48c64891bf954f678a62f8f790bbd86 258 Gene3D G3DSA:1.10.510.10 156 258 1.6E-27 T 23-10-2018 A0127_01085 b48c64891bf954f678a62f8f790bbd86 258 ProSitePatterns PS00109 Tyrosine protein kinases specific active-site signature. 191 203 - T 23-10-2018 IPR008266 Tyrosine-protein kinase, active site GO:0004672|GO:0006468 A0127_01085 b48c64891bf954f678a62f8f790bbd86 258 SUPERFAMILY SSF56112 40 248 7.4E-23 T 23-10-2018 IPR011009 Protein kinase-like domain superfamily A0127_01085 b48c64891bf954f678a62f8f790bbd86 258 Pfam PF01163 RIO1 family 65 246 1.6E-55 T 23-10-2018 A0127_01085 b48c64891bf954f678a62f8f790bbd86 258 Gene3D G3DSA:3.30.200.20 51 151 1.5E-12 T 23-10-2018 A0127_02705 e654a69f09240d900a6a4827b39f1a8a 357 SMART SM00471 46 156 4.5E-14 T 23-10-2018 IPR003607 HD/PDEase domain A0127_02705 e654a69f09240d900a6a4827b39f1a8a 357 SUPERFAMILY SSF109604 1 342 1.57E-83 T 23-10-2018 A0127_02705 e654a69f09240d900a6a4827b39f1a8a 357 Gene3D G3DSA:1.10.3210.10 1 279 2.3E-75 T 23-10-2018 A0127_02705 e654a69f09240d900a6a4827b39f1a8a 357 Pfam PF01966 HD domain 50 102 4.0E-8 T 23-10-2018 IPR006674 HD domain A0127_06025 88125627920ff77867b54747f1dc0139 668 Pfam PF04312 Protein of unknown function (DUF460) 207 347 5.5E-49 T 23-10-2018 IPR007408 Protein of unknown function DUF460 A0127_01585 3e5c7ce94b7a69c2fa41a3b0650a6875 337 Gene3D G3DSA:3.40.910.10 2 337 1.4E-146 T 23-10-2018 IPR036982 Deoxyhypusine synthase superfamily GO:0008612 Reactome: R-HSA-204626 A0127_01585 3e5c7ce94b7a69c2fa41a3b0650a6875 337 SUPERFAMILY SSF52467 5 334 3.11E-117 T 23-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily A0127_01585 3e5c7ce94b7a69c2fa41a3b0650a6875 337 TIGRFAM TIGR00321 dhys: deoxyhypusine synthase 20 335 2.0E-122 T 23-10-2018 IPR002773 Deoxyhypusine synthase GO:0008612 Reactome: R-HSA-204626 A0127_01585 3e5c7ce94b7a69c2fa41a3b0650a6875 337 Hamap MF_00153 Probable deoxyhypusine synthase [dys]. 31 334 42.603 T 23-10-2018 IPR022899 Deoxyhypusine synthase, putative, archaeal GO:0034038 A0127_01585 3e5c7ce94b7a69c2fa41a3b0650a6875 337 Pfam PF01916 Deoxyhypusine synthase 34 331 3.1E-113 T 23-10-2018 IPR002773 Deoxyhypusine synthase GO:0008612 Reactome: R-HSA-204626 A0127_01945 52035ec540c365ca3c4d45bb0337a66d 331 Gene3D G3DSA:3.40.630.10 8 324 1.8E-114 T 23-10-2018 A0127_01945 52035ec540c365ca3c4d45bb0337a66d 331 PIRSF PIRSF001123 1 331 2.0E-86 T 23-10-2018 IPR008007 Peptidase M42 A0127_01945 52035ec540c365ca3c4d45bb0337a66d 331 SUPERFAMILY SSF53187 2 330 7.26E-54 T 23-10-2018 A0127_01945 52035ec540c365ca3c4d45bb0337a66d 331 Gene3D G3DSA:2.40.30.40 64 155 1.8E-114 T 23-10-2018 IPR023367 Peptidase M42, domain 2 A0127_01945 52035ec540c365ca3c4d45bb0337a66d 331 Pfam PF05343 M42 glutamyl aminopeptidase 42 323 8.0E-85 T 23-10-2018 IPR008007 Peptidase M42 A0127_01945 52035ec540c365ca3c4d45bb0337a66d 331 SUPERFAMILY SSF101821 65 172 1.83E-21 T 23-10-2018 A0127_05650 04d616760a0e389f5a5ce5a8a553284b 148 Gene3D G3DSA:2.30.130.30 1 136 3.6E-52 T 23-10-2018 A0127_05650 04d616760a0e389f5a5ce5a8a553284b 148 PIRSF PIRSF006031 3 146 2.1E-64 T 23-10-2018 IPR007176 Protein of unknown function DUF365 A0127_05650 04d616760a0e389f5a5ce5a8a553284b 148 Pfam PF04033 Domain of unknown function (DUF365) 40 135 2.6E-36 T 23-10-2018 IPR007176 Protein of unknown function DUF365 A0127_05650 04d616760a0e389f5a5ce5a8a553284b 148 ProDom PD020174 PH0907 MJECS03 PLASMID PF0569 AF2351 40 145 8.0E-30 T 23-10-2018 IPR007176 Protein of unknown function DUF365 A0127_01955 f5d695473aa51de2c3e79536704b28b3 481 TIGRFAM TIGR00408 proS_fam_I: proline--tRNA ligase 9 481 4.2E-184 T 23-10-2018 IPR004499 Proline-tRNA ligase, class IIa, archaeal-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 A0127_01955 f5d695473aa51de2c3e79536704b28b3 481 Pfam PF09180 Prolyl-tRNA synthetase, C-terminal 411 481 5.8E-18 T 23-10-2018 IPR016061 Proline-tRNA ligase, class II, C-terminal GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 A0127_01955 f5d695473aa51de2c3e79536704b28b3 481 SUPERFAMILY SSF52954 278 402 8.61E-38 T 23-10-2018 A0127_01955 f5d695473aa51de2c3e79536704b28b3 481 PRINTS PR01046 Prolyl-tRNA synthetase signature 105 116 1.9E-12 T 23-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 A0127_01955 f5d695473aa51de2c3e79536704b28b3 481 PRINTS PR01046 Prolyl-tRNA synthetase signature 64 82 1.9E-12 T 23-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 A0127_01955 f5d695473aa51de2c3e79536704b28b3 481 PRINTS PR01046 Prolyl-tRNA synthetase signature 145 156 1.9E-12 T 23-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 A0127_01955 f5d695473aa51de2c3e79536704b28b3 481 PRINTS PR01046 Prolyl-tRNA synthetase signature 135 143 1.9E-12 T 23-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 A0127_01955 f5d695473aa51de2c3e79536704b28b3 481 Gene3D G3DSA:3.30.110.30 404 480 1.8E-20 T 23-10-2018 IPR017449 Prolyl-tRNA synthetase, class II GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 A0127_01955 f5d695473aa51de2c3e79536704b28b3 481 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 99 271 5.3E-24 T 23-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 A0127_01955 f5d695473aa51de2c3e79536704b28b3 481 Pfam PF03129 Anticodon binding domain 289 383 1.0E-22 T 23-10-2018 IPR004154 Anticodon-binding A0127_01955 f5d695473aa51de2c3e79536704b28b3 481 SMART SM00946 410 481 1.3E-26 T 23-10-2018 IPR016061 Proline-tRNA ligase, class II, C-terminal GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 A0127_01955 f5d695473aa51de2c3e79536704b28b3 481 SUPERFAMILY SSF64586 405 481 3.53E-22 T 23-10-2018 IPR017449 Prolyl-tRNA synthetase, class II GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 A0127_01955 f5d695473aa51de2c3e79536704b28b3 481 Gene3D G3DSA:3.40.50.800 283 401 1.5E-37 T 23-10-2018 IPR036621 Anticodon-binding domain superfamily A0127_01955 f5d695473aa51de2c3e79536704b28b3 481 Hamap MF_01571 Proline--tRNA ligase [proS]. 5 481 41.721 T 23-10-2018 IPR004499 Proline-tRNA ligase, class IIa, archaeal-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 A0127_01955 f5d695473aa51de2c3e79536704b28b3 481 SUPERFAMILY SSF55681 10 276 4.4E-76 T 23-10-2018 A0127_01955 f5d695473aa51de2c3e79536704b28b3 481 Gene3D G3DSA:3.30.930.10 11 282 6.1E-86 T 23-10-2018 A0127_06005 d348c5b17d8a951b5bed8fc297523199 111 SMART SM01022 6 109 3.3E-17 T 23-10-2018 IPR007374 ASCH domain A0127_06005 d348c5b17d8a951b5bed8fc297523199 111 PIRSF PIRSF016134 2 111 6.1E-48 T 23-10-2018 IPR016645 Uncharacterised conserved protein UCP016134 A0127_06005 d348c5b17d8a951b5bed8fc297523199 111 Pfam PF04266 ASCH domain 6 108 1.2E-17 T 23-10-2018 IPR007374 ASCH domain A0127_06005 d348c5b17d8a951b5bed8fc297523199 111 Gene3D G3DSA:2.30.130.30 2 109 1.1E-43 T 23-10-2018 A0127_06005 d348c5b17d8a951b5bed8fc297523199 111 SUPERFAMILY SSF88697 1 109 3.15E-37 T 23-10-2018 IPR015947 PUA-like superfamily A0127_01205 da60f8e1c1fd22d0a2cebc2b52a1d791 282 Hamap MF_02055 Tyrosine recombinase XerA [xerA]. 4 274 41.873 T 23-10-2018 IPR033686 Tyrosine recombinase XerA A0127_01205 da60f8e1c1fd22d0a2cebc2b52a1d791 282 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 8 77 5.1E-9 T 23-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 A0127_01205 da60f8e1c1fd22d0a2cebc2b52a1d791 282 Pfam PF00589 Phage integrase family 99 262 2.2E-49 T 23-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 A0127_01205 da60f8e1c1fd22d0a2cebc2b52a1d791 282 Gene3D G3DSA:1.10.150.130 2 90 1.9E-20 T 23-10-2018 IPR010998 Integrase/recombinase, N-terminal A0127_01205 da60f8e1c1fd22d0a2cebc2b52a1d791 282 Gene3D G3DSA:1.10.443.10 91 282 8.6E-77 T 23-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 A0127_01205 da60f8e1c1fd22d0a2cebc2b52a1d791 282 SUPERFAMILY SSF56349 6 270 2.3E-59 T 23-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A0127_09260 092eb319cc720c884c14ef99005d998c 90 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 34 45 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A0127_09260 092eb319cc720c884c14ef99005d998c 90 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 71 82 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A0127_09260 092eb319cc720c884c14ef99005d998c 90 SUPERFAMILY SSF54862 20 89 1.98E-15 T 23-10-2018 A0127_09260 092eb319cc720c884c14ef99005d998c 90 Pfam PF12838 4Fe-4S dicluster domain 34 82 3.2E-11 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A0127_09260 092eb319cc720c884c14ef99005d998c 90 Gene3D G3DSA:3.30.70.20 2 90 1.2E-16 T 23-10-2018 A0127_03610 297f5ae5e6a5914f621fe8b67267997f 189 Pfam PF04266 ASCH domain 4 104 8.2E-18 T 23-10-2018 IPR007374 ASCH domain A0127_03610 297f5ae5e6a5914f621fe8b67267997f 189 SMART SM01022 4 104 1.0E-25 T 23-10-2018 IPR007374 ASCH domain A0127_03610 297f5ae5e6a5914f621fe8b67267997f 189 SUPERFAMILY SSF88697 2 103 3.98E-22 T 23-10-2018 IPR015947 PUA-like superfamily A0127_10065 84df8847c5a5ad5aaf9cdbfa6528646d 365 Pfam PF01758 Sodium Bile acid symporter family 53 254 4.1E-47 T 23-10-2018 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 A0127_10065 84df8847c5a5ad5aaf9cdbfa6528646d 365 Gene3D G3DSA:1.20.1530.20 3 344 1.7E-23 T 23-10-2018 IPR038770 Sodium/solute symporter superfamily A0127_10065 84df8847c5a5ad5aaf9cdbfa6528646d 365 PIRSF PIRSF005508 1 357 5.3E-141 T 23-10-2018 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 A0127_10065 84df8847c5a5ad5aaf9cdbfa6528646d 365 TIGRFAM TIGR00832 acr3: arsenical-resistance protein 7 342 2.1E-118 T 23-10-2018 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 A0127_02565 9e697464c47f10f5f4524115865fb9d8 259 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 6 212 6.2E-25 T 23-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain A0127_02565 9e697464c47f10f5f4524115865fb9d8 259 SMART SM00382 3 163 0.0011 T 23-10-2018 IPR003593 AAA+ ATPase domain A0127_02565 9e697464c47f10f5f4524115865fb9d8 259 SUPERFAMILY SSF52540 3 236 1.45E-57 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_02565 9e697464c47f10f5f4524115865fb9d8 259 Gene3D G3DSA:3.40.50.300 4 233 2.9E-66 T 23-10-2018 A0127_02565 9e697464c47f10f5f4524115865fb9d8 259 TIGRFAM TIGR01969 minD_arch: cell division ATPase MinD 4 251 1.9E-117 T 23-10-2018 IPR010224 ATP binding protein MinD, archaea A0127_02565 9e697464c47f10f5f4524115865fb9d8 259 PIRSF PIRSF003092 1 259 2.0E-65 T 23-10-2018 IPR025501 ATP binding protein MinD A0127_09745 3b827bbba2a7f410b976ddb8094d4693 193 Pfam PF03956 Lysine exporter LysO 9 190 1.2E-56 T 23-10-2018 IPR005642 Lysine exporter LysO A0127_09745 3b827bbba2a7f410b976ddb8094d4693 193 ProDom PD022789 MEMBRANE SURFACE PRECURSOR SIGNAL PROTEIN YBJE TRANSMEMBRANE INNER PREDICTED STY0934 24 193 5.0E-59 T 23-10-2018 IPR005642 Lysine exporter LysO A0127_03530 b23316e5c2e074b720c700002d9f2a5a 65 Gene3D G3DSA:1.10.260.40 1 65 1.6E-32 T 23-10-2018 A0127_03530 b23316e5c2e074b720c700002d9f2a5a 65 SUPERFAMILY SSF47413 3 64 5.36E-22 T 23-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A0127_03530 b23316e5c2e074b720c700002d9f2a5a 65 SMART SM00530 4 59 5.7E-22 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A0127_03530 b23316e5c2e074b720c700002d9f2a5a 65 Pfam PF01381 Helix-turn-helix 5 58 3.9E-21 T 23-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 A0127_01360 b6e0b4ea84ead204f38b45fe6e8a3f4c 264 Pfam PF01889 Membrane protein of unknown function DUF63 7 263 8.8E-78 T 23-10-2018 IPR002749 Protein of unknown function DUF63 A0127_06745 967e6cc18f8b56ad2f7f998fecaa9588 178 SUPERFAMILY SSF50324 1 176 1.57E-67 T 23-10-2018 IPR036649 Inorganic pyrophosphatase superfamily GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 A0127_06745 967e6cc18f8b56ad2f7f998fecaa9588 178 Gene3D G3DSA:3.90.80.10 1 178 1.9E-75 T 23-10-2018 IPR036649 Inorganic pyrophosphatase superfamily GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 A0127_06745 967e6cc18f8b56ad2f7f998fecaa9588 178 Hamap MF_00209 Inorganic pyrophosphatase [ppa]. 15 171 36.667 T 23-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 A0127_06745 967e6cc18f8b56ad2f7f998fecaa9588 178 ProSitePatterns PS00387 Inorganic pyrophosphatase signature. 66 72 - T 23-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 A0127_06745 967e6cc18f8b56ad2f7f998fecaa9588 178 Pfam PF00719 Inorganic pyrophosphatase 20 171 2.8E-58 T 23-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 A0127_02675 7f9b5f03abda1951d95a9ad5b2538a24 99 Pfam PF11505 Protein of unknown function (DUF3216) 7 97 5.2E-45 T 23-10-2018 IPR023108 Domain of unknown function, DUF3216 A0127_02675 7f9b5f03abda1951d95a9ad5b2538a24 99 Gene3D G3DSA:1.20.120.460 3 99 1.0E-34 T 23-10-2018 IPR038317 Pf1176-like superfamily A0127_03685 afdb7b13e08ee6594aab085a4df29c01 220 TIGRFAM TIGR02537 arch_flag_Nterm: archaeal flagellin N-terminal-like domain 6 29 4.1E-6 T 23-10-2018 IPR013373 Flagellin/pilin, N-terminal A0127_03685 afdb7b13e08ee6594aab085a4df29c01 220 Pfam PF01917 Archaebacterial flagellin 8 206 3.4E-52 T 23-10-2018 IPR002774 Flagellin, archaea GO:0005198|GO:0006928 A0127_04265 dd690d04bd8b9fd43358f38cc99d27de 326 SUPERFAMILY SSF48019 235 324 4.42E-24 T 23-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 A0127_04265 dd690d04bd8b9fd43358f38cc99d27de 326 Gene3D G3DSA:3.40.50.300 2 169 4.2E-63 T 23-10-2018 A0127_04265 dd690d04bd8b9fd43358f38cc99d27de 326 SUPERFAMILY SSF52540 12 227 5.1E-60 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_04265 dd690d04bd8b9fd43358f38cc99d27de 326 Hamap MF_01509 Replication factor C small subunit [rfcS]. 11 325 51.564 T 23-10-2018 IPR023748 Replication factor C small subunit, archaeal GO:0003689|GO:0005524|GO:0005663|GO:0006260 A0127_04265 dd690d04bd8b9fd43358f38cc99d27de 326 Gene3D G3DSA:1.10.8.60 170 233 6.2E-27 T 23-10-2018 A0127_04265 dd690d04bd8b9fd43358f38cc99d27de 326 Gene3D G3DSA:1.20.272.10 234 326 4.2E-37 T 23-10-2018 A0127_04265 dd690d04bd8b9fd43358f38cc99d27de 326 SMART SM00382 45 176 3.9E-15 T 23-10-2018 IPR003593 AAA+ ATPase domain A0127_04265 dd690d04bd8b9fd43358f38cc99d27de 326 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 49 167 1.2E-18 T 23-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 A0127_04265 dd690d04bd8b9fd43358f38cc99d27de 326 Pfam PF08542 Replication factor C C-terminal domain 235 320 7.2E-22 T 23-10-2018 IPR013748 Replication factor C, C-terminal Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-176187|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804756|Reactome: R-HSA-69091|Reactome: R-HSA-69473 A0127_05885 60d9e99a5a06a3a42f8f43e9bc9b7496 225 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 17 217 8.7E-71 T 23-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 A0127_05885 60d9e99a5a06a3a42f8f43e9bc9b7496 225 SUPERFAMILY SSF56529 13 217 1.01E-80 T 23-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 A0127_05885 60d9e99a5a06a3a42f8f43e9bc9b7496 225 Gene3D G3DSA:3.90.850.10 4 220 3.7E-91 T 23-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 A0127_05860 4d6fa254207bc9dd3843742186bb7249 147 Pfam PF01850 PIN domain 5 136 1.2E-22 T 23-10-2018 IPR002716 PIN domain A0127_05860 4d6fa254207bc9dd3843742186bb7249 147 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 5 142 10.848 T 23-10-2018 IPR022907 VapC family GO:0004540 A0127_05860 4d6fa254207bc9dd3843742186bb7249 147 SUPERFAMILY SSF88723 2 142 9.53E-21 T 23-10-2018 IPR029060 PIN-like domain superfamily A0127_05860 4d6fa254207bc9dd3843742186bb7249 147 Gene3D G3DSA:3.40.50.1010 2 142 2.8E-13 T 23-10-2018 A0127_05860 4d6fa254207bc9dd3843742186bb7249 147 SMART SM00670 3 134 4.4E-18 T 23-10-2018 IPR002716 PIN domain A0127_03235 987e068b89144dbe4a3003eb53821c7d 168 Pfam PF09622 Putative integral membrane protein (DUF2391) 32 163 1.2E-11 T 23-10-2018 IPR024464 Protein of unknown function DUF2391 A0127_00165 7302a556d65bb05870b4bc397cbbb359 579 Pfam PF02554 Carbon starvation protein CstA 1 361 8.1E-111 T 23-10-2018 IPR003706 CstA, N-terminal domain GO:0009267|GO:0016020 A0127_00165 7302a556d65bb05870b4bc397cbbb359 579 Pfam PF13722 5TM C-terminal transporter carbon starvation CstA 404 527 8.8E-31 T 23-10-2018 IPR025299 CstA, C-terminal domain A0127_09440 8d939188f1a31b59686f55721e006462 84 SUPERFAMILY SSF159127 3 65 6.54E-12 T 23-10-2018 IPR037254 HupF/HypC superfamily A0127_09440 8d939188f1a31b59686f55721e006462 84 Pfam PF01455 HupF/HypC family 3 63 2.6E-13 T 23-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC A0127_09440 8d939188f1a31b59686f55721e006462 84 Gene3D G3DSA:2.40.50.970 1 70 4.2E-15 T 23-10-2018 IPR037254 HupF/HypC superfamily A0127_06135 bafc371643f7c412b4e15d07ebcf2e52 410 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 14 391 4.9E-117 T 23-10-2018 A0127_06135 bafc371643f7c412b4e15d07ebcf2e52 410 SUPERFAMILY SSF51338 336 398 3.17E-19 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A0127_06135 bafc371643f7c412b4e15d07ebcf2e52 410 Pfam PF01979 Amidohydrolase family 49 388 5.4E-15 T 23-10-2018 IPR006680 Amidohydrolase-related GO:0016787 A0127_06135 bafc371643f7c412b4e15d07ebcf2e52 410 ProSitePatterns PS00483 Dihydroorotase signature 2. 275 286 - T 23-10-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A0127_06135 bafc371643f7c412b4e15d07ebcf2e52 410 Gene3D G3DSA:3.20.20.140 43 406 1.9E-104 T 23-10-2018 A0127_06135 bafc371643f7c412b4e15d07ebcf2e52 410 Hamap MF_00220_A Dihydroorotase [pyrC]. 4 396 64.067 T 23-10-2018 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 A0127_06135 bafc371643f7c412b4e15d07ebcf2e52 410 SUPERFAMILY SSF51556 53 335 1.15E-72 T 23-10-2018 IPR032466 Metal-dependent hydrolase A0127_06135 bafc371643f7c412b4e15d07ebcf2e52 410 SUPERFAMILY SSF51338 19 62 5.61E-6 T 23-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 A0127_01230 db8216d2bcaf9eabfbb7188029063244 165 SUPERFAMILY SSF46785 7 99 8.25E-23 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A0127_01230 db8216d2bcaf9eabfbb7188029063244 165 Pfam PF03551 Transcriptional regulator PadR-like family 24 97 3.8E-16 T 23-10-2018 IPR005149 Transcription regulator PadR, N-terminal A0127_01230 db8216d2bcaf9eabfbb7188029063244 165 Gene3D G3DSA:1.10.10.10 15 114 1.7E-17 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A0127_00650 dc3c028e9bfb41636191f8776c9c9474 573 SMART SM00116 452 500 4.0E-8 T 23-10-2018 IPR000644 CBS domain A0127_00650 dc3c028e9bfb41636191f8776c9c9474 573 SMART SM00116 513 564 0.0017 T 23-10-2018 IPR000644 CBS domain A0127_00650 dc3c028e9bfb41636191f8776c9c9474 573 SUPERFAMILY SSF81340 10 432 3.92E-100 T 23-10-2018 IPR014743 Chloride channel, core Reactome: R-HSA-2672351 A0127_00650 dc3c028e9bfb41636191f8776c9c9474 573 Gene3D G3DSA:1.10.3080.10 5 433 1.9E-97 T 23-10-2018 IPR014743 Chloride channel, core Reactome: R-HSA-2672351 A0127_00650 dc3c028e9bfb41636191f8776c9c9474 573 Pfam PF00654 Voltage gated chloride channel 69 412 3.2E-87 T 23-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 A0127_00650 dc3c028e9bfb41636191f8776c9c9474 573 SUPERFAMILY SSF54631 439 564 9.39E-27 T 23-10-2018 A0127_00650 dc3c028e9bfb41636191f8776c9c9474 573 PRINTS PR00762 Chloride channel signature 362 378 1.1E-17 T 23-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 A0127_00650 dc3c028e9bfb41636191f8776c9c9474 573 PRINTS PR00762 Chloride channel signature 327 347 1.1E-17 T 23-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 A0127_00650 dc3c028e9bfb41636191f8776c9c9474 573 PRINTS PR00762 Chloride channel signature 380 399 1.1E-17 T 23-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 A0127_00650 dc3c028e9bfb41636191f8776c9c9474 573 PRINTS PR00762 Chloride channel signature 82 99 1.1E-17 T 23-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 A0127_00650 dc3c028e9bfb41636191f8776c9c9474 573 PRINTS PR00762 Chloride channel signature 162 181 1.1E-17 T 23-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 A0127_00650 dc3c028e9bfb41636191f8776c9c9474 573 Gene3D G3DSA:3.10.580.10 438 566 2.3E-24 T 23-10-2018 A0127_00650 dc3c028e9bfb41636191f8776c9c9474 573 Pfam PF00571 CBS domain 511 562 4.1E-7 T 23-10-2018 IPR000644 CBS domain A0127_00650 dc3c028e9bfb41636191f8776c9c9474 573 Pfam PF00571 CBS domain 445 497 4.0E-12 T 23-10-2018 IPR000644 CBS domain A0127_09565 8a532fcd687a62f994c54e83b2a02e9e 334 TIGRFAM TIGR00816 tdt: C4-dicarboxylate transporter/malic acid transport protein 8 326 1.2E-80 T 23-10-2018 IPR011552 Tellurite resistance protein TehA/malic acid transport protein GO:0016021 A0127_09565 8a532fcd687a62f994c54e83b2a02e9e 334 Gene3D G3DSA:1.50.10.150 2 329 4.5E-37 T 23-10-2018 IPR038665 Voltage-dependent anion channel superfamily A0127_09565 8a532fcd687a62f994c54e83b2a02e9e 334 Pfam PF03595 Voltage-dependent anion channel 7 325 4.0E-63 T 23-10-2018 IPR004695 Voltage-dependent anion channel GO:0016021|GO:0055085 A0127_05810 a80c4bf9caac0feab78a9c652f56300a 185 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 45 60 3.3E-5 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A0127_05810 a80c4bf9caac0feab78a9c652f56300a 185 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 13 28 3.3E-5 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A0127_05810 a80c4bf9caac0feab78a9c652f56300a 185 Pfam PF01022 Bacterial regulatory protein, arsR family 18 63 8.3E-14 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A0127_05810 a80c4bf9caac0feab78a9c652f56300a 185 SUPERFAMILY SSF46785 1 129 7.49E-24 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A0127_05810 a80c4bf9caac0feab78a9c652f56300a 185 SMART SM00418 11 86 8.5E-11 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A0127_05810 a80c4bf9caac0feab78a9c652f56300a 185 Gene3D G3DSA:1.10.10.10 1 85 9.6E-22 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A0127_08215 54ef9ad63da0314136af3d66e7850398 230 Gene3D G3DSA:3.40.50.1000 3 137 1.8E-12 T 23-10-2018 IPR023214 HAD superfamily A0127_08215 54ef9ad63da0314136af3d66e7850398 230 SUPERFAMILY SSF56784 1 185 7.2E-19 T 23-10-2018 IPR036412 HAD-like superfamily A0127_08215 54ef9ad63da0314136af3d66e7850398 230 Gene3D G3DSA:1.10.150.240 14 83 1.8E-12 T 23-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 A0127_08215 54ef9ad63da0314136af3d66e7850398 230 Pfam PF13419 Haloacid dehalogenase-like hydrolase 3 135 2.7E-12 T 23-10-2018 A0127_07525 b352d33060b3614c1e15fb72f440d6ad 141 Pfam PF00238 Ribosomal protein L14p/L23e 24 140 4.6E-35 T 23-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 A0127_07525 b352d33060b3614c1e15fb72f440d6ad 141 SMART SM01374 20 141 2.4E-57 T 23-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 A0127_07525 b352d33060b3614c1e15fb72f440d6ad 141 Gene3D G3DSA:2.40.150.20 1 140 3.3E-49 T 23-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 A0127_07525 b352d33060b3614c1e15fb72f440d6ad 141 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 20 141 19.42 T 23-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 A0127_07525 b352d33060b3614c1e15fb72f440d6ad 141 TIGRFAM TIGR03673 uL14_arch: 50S ribosomal protein uL14 15 140 5.8E-61 T 23-10-2018 IPR019971 Ribosomal protein L14P, archaeal A0127_07525 b352d33060b3614c1e15fb72f440d6ad 141 SUPERFAMILY SSF50193 16 141 2.22E-44 T 23-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 A0127_01780 f23c590ad0fd92f0cc1b4caeddae1cf6 266 Pfam PF02457 DisA bacterial checkpoint controller nucleotide-binding 132 254 2.4E-22 T 23-10-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal A0127_01780 f23c590ad0fd92f0cc1b4caeddae1cf6 266 Gene3D G3DSA:3.40.1700.10 170 265 1.7E-14 T 23-10-2018 IPR036888 DNA integrity scanning protein, DisA, N-terminal domain superfamily A0127_01780 f23c590ad0fd92f0cc1b4caeddae1cf6 266 Hamap MF_00840 Diadenylate cyclase [dacZ]. 7 265 35.197 T 23-10-2018 IPR014499 Diadenylate cyclase, DacZ-type A0127_01780 f23c590ad0fd92f0cc1b4caeddae1cf6 266 SUPERFAMILY SSF143597 104 259 5.49E-30 T 23-10-2018 IPR036888 DNA integrity scanning protein, DisA, N-terminal domain superfamily A0127_01780 f23c590ad0fd92f0cc1b4caeddae1cf6 266 PIRSF PIRSF019073 1 266 3.7E-77 T 23-10-2018 IPR014499 Diadenylate cyclase, DacZ-type A0127_02235 d3e37399f5f86ca2ea4d6e6083108eb4 387 Pfam PF00474 Sodium:solute symporter family 5 334 4.7E-43 T 23-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 A0127_02235 d3e37399f5f86ca2ea4d6e6083108eb4 387 ProSitePatterns PS00457 Sodium:solute symporter family signature 2. 316 336 - T 23-10-2018 IPR018212 Sodium/solute symporter, conserved site A0127_02235 d3e37399f5f86ca2ea4d6e6083108eb4 387 Gene3D G3DSA:1.20.1730.10 1 385 3.9E-73 T 23-10-2018 IPR038377 Sodium/glucose symporter superfamily A0127_05790 f3ba1168abdf5563ae98dc995441698d 687 Pfam PF08308 PEGA domain 420 481 1.8E-9 T 23-10-2018 IPR013229 PEGA A0127_05790 f3ba1168abdf5563ae98dc995441698d 687 Pfam PF08308 PEGA domain 557 621 1.3E-11 T 23-10-2018 IPR013229 PEGA A0127_05790 f3ba1168abdf5563ae98dc995441698d 687 TIGRFAM TIGR04288 CGP_CTERM: CGP-CTERM domain 663 682 2.4E-4 T 23-10-2018 IPR027552 CGP-CTERM domain A0127_08015 7dbfa620789b6d73f4019609629000bb 198 TIGRFAM TIGR03875 RNA_lig_partner: RNA ligase partner, MJ_0950 family 2 189 5.2E-70 T 23-10-2018 IPR014856 PIN-domain ribonuclease A0127_08015 7dbfa620789b6d73f4019609629000bb 198 Hamap MF_01078 UPF0278 protein . 1 193 29.402 T 23-10-2018 IPR014856 PIN-domain ribonuclease A0127_08015 7dbfa620789b6d73f4019609629000bb 198 SUPERFAMILY SSF88723 70 178 4.77E-7 T 23-10-2018 IPR029060 PIN-like domain superfamily A0127_08015 7dbfa620789b6d73f4019609629000bb 198 Pfam PF08745 PINc domain ribonuclease 2 190 2.3E-65 T 23-10-2018 IPR014856 PIN-domain ribonuclease A0127_02340 48dba0628559376cf747323b842cd99d 98 SMART SM00661 13 63 0.008 T 23-10-2018 IPR001529 DNA-directed RNA polymerase, M/15kDa subunit GO:0006351 A0127_02340 48dba0628559376cf747323b842cd99d 98 Pfam PF06677 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) 3 35 1.1E-13 T 23-10-2018 IPR009563 Sjoegren syndrome/scleroderma autoantigen 1 A0127_05205 81413f0d86e08ac2d939b2815ff9464b 75 Pfam PF01037 Lrp/AsnC ligand binding domain 9 74 1.2E-19 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A0127_05205 81413f0d86e08ac2d939b2815ff9464b 75 SUPERFAMILY SSF54909 1 74 2.41E-18 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel A0127_05205 81413f0d86e08ac2d939b2815ff9464b 75 Gene3D G3DSA:3.30.70.920 1 74 1.4E-27 T 23-10-2018 A0127_10225 52be0bf07bebcafeb5bf9b68d54a46a3 172 Pfam PF03773 Predicted permease 38 160 1.2E-11 T 23-10-2018 IPR005524 Predicted permease DUF318 A0127_09270 db6a21d36eb7f609f34fca80d58c958f 284 SUPERFAMILY SSF52518 19 274 2.03E-75 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold A0127_09270 db6a21d36eb7f609f34fca80d58c958f 284 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 57 205 4.9E-40 T 23-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 A0127_09270 db6a21d36eb7f609f34fca80d58c958f 284 Gene3D G3DSA:3.40.50.970 69 261 3.9E-33 T 23-10-2018 A0127_09210 5ce5197e2ce220fbe4de26d3607c95c7 156 Pfam PF03551 Transcriptional regulator PadR-like family 14 84 1.2E-19 T 23-10-2018 IPR005149 Transcription regulator PadR, N-terminal A0127_09210 5ce5197e2ce220fbe4de26d3607c95c7 156 Gene3D G3DSA:1.10.10.10 1 104 1.6E-27 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A0127_09210 5ce5197e2ce220fbe4de26d3607c95c7 156 SUPERFAMILY SSF46785 10 138 1.15E-28 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A0127_09705 6d5440a18eb116cf60efb32335fcb070 111 Pfam PF13190 PDGLE domain 29 100 2.3E-8 T 23-10-2018 IPR025937 PDGLE domain A0127_09705 6d5440a18eb116cf60efb32335fcb070 111 ProDom PD074023 BIOSYNTHESIS COBALAMIN CBIM COBALT PRECURSOR SIGNAL NICKEL MEMBRANE ABC PROTEIN 8 107 4.0E-22 T 23-10-2018 IPR020486 Probable fused nickel transport protein LarMN-like A0127_06655 b159d0a4f3498ce4c611cbe3ef5468fb 181 SUPERFAMILY SSF52540 6 177 3.55E-37 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_06655 b159d0a4f3498ce4c611cbe3ef5468fb 181 Hamap MF_00065 Adenylyl-sulfate kinase [cysC]. 8 178 36.897 T 23-10-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 A0127_06655 b159d0a4f3498ce4c611cbe3ef5468fb 181 Pfam PF01583 Adenylylsulphate kinase 9 160 3.6E-59 T 23-10-2018 A0127_06655 b159d0a4f3498ce4c611cbe3ef5468fb 181 TIGRFAM TIGR00455 apsK: adenylyl-sulfate kinase 3 172 4.2E-68 T 23-10-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 A0127_06655 b159d0a4f3498ce4c611cbe3ef5468fb 181 Gene3D G3DSA:3.40.50.300 5 181 1.0E-60 T 23-10-2018 A0127_03275 d3462b662d742821ec7bc9938433fcd2 492 Gene3D G3DSA:3.50.50.60 218 308 2.2E-152 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A0127_03275 d3462b662d742821ec7bc9938433fcd2 492 Gene3D G3DSA:1.10.10.1100 397 473 2.2E-152 T 23-10-2018 A0127_03275 d3462b662d742821ec7bc9938433fcd2 492 Gene3D G3DSA:3.10.20.440 1 95 1.6E-37 T 23-10-2018 A0127_03275 d3462b662d742821ec7bc9938433fcd2 492 Gene3D G3DSA:3.50.50.60 110 480 2.2E-152 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A0127_03275 d3462b662d742821ec7bc9938433fcd2 492 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 300 316 4.2E-6 T 23-10-2018 A0127_03275 d3462b662d742821ec7bc9938433fcd2 492 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 111 130 4.2E-6 T 23-10-2018 A0127_03275 d3462b662d742821ec7bc9938433fcd2 492 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 206 224 4.2E-6 T 23-10-2018 A0127_03275 d3462b662d742821ec7bc9938433fcd2 492 SUPERFAMILY SSF51905 109 367 4.1E-22 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A0127_03275 d3462b662d742821ec7bc9938433fcd2 492 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 259 351 1.9E-8 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A0127_03275 d3462b662d742821ec7bc9938433fcd2 492 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 110 225 1.9E-10 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A0127_03275 d3462b662d742821ec7bc9938433fcd2 492 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 13 88 4.0E-14 T 23-10-2018 A0127_03670 746640ba18a4e8837f451a44bb0ccaef 158 Pfam PF05377 Flagella accessory protein C (FlaC) 49 102 4.6E-21 T 23-10-2018 IPR009205 Predicted archaeal flagellar protein C A0127_03670 746640ba18a4e8837f451a44bb0ccaef 158 Gene3D G3DSA:1.20.5.340 16 142 7.4E-7 T 23-10-2018 A0127_03670 746640ba18a4e8837f451a44bb0ccaef 158 PIRSF PIRSF018660 6 158 7.5E-19 T 23-10-2018 IPR009205 Predicted archaeal flagellar protein C A0127_08370 d3e093d997be64bf7ce3efeef08075f0 399 Pfam PF00266 Aminotransferase class-V 18 386 3.6E-138 T 23-10-2018 IPR000192 Aminotransferase class V domain A0127_08370 d3e093d997be64bf7ce3efeef08075f0 399 PIRSF PIRSF005572 15 399 1.9E-49 T 23-10-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 A0127_08370 d3e093d997be64bf7ce3efeef08075f0 399 SUPERFAMILY SSF53383 5 395 1.22E-117 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A0127_08370 d3e093d997be64bf7ce3efeef08075f0 399 Gene3D G3DSA:3.40.640.10 29 287 5.7E-146 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A0127_08370 d3e093d997be64bf7ce3efeef08075f0 399 Gene3D G3DSA:3.90.1150.10 7 387 5.7E-146 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A0127_04385 e510790ef3b7d045edcae85ece0e3f7f 190 Gene3D G3DSA:3.40.50.300 1 190 4.2E-42 T 23-10-2018 A0127_04385 e510790ef3b7d045edcae85ece0e3f7f 190 Pfam PF13238 AAA domain 3 138 1.5E-17 T 23-10-2018 A0127_04385 e510790ef3b7d045edcae85ece0e3f7f 190 SUPERFAMILY SSF52540 1 188 2.81E-19 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_01530 d4ece0ecda7ff1558922fb8b5c765974 242 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 94 195 2.1E-14 T 23-10-2018 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 A0127_01530 d4ece0ecda7ff1558922fb8b5c765974 242 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 98 193 3.1E-12 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A0127_01530 d4ece0ecda7ff1558922fb8b5c765974 242 Gene3D G3DSA:3.40.50.1000 3 220 6.3E-87 T 23-10-2018 IPR023214 HAD superfamily A0127_01530 d4ece0ecda7ff1558922fb8b5c765974 242 Gene3D G3DSA:1.10.150.520 16 94 6.3E-87 T 23-10-2018 A0127_01530 d4ece0ecda7ff1558922fb8b5c765974 242 TIGRFAM TIGR02253 CTE7: HAD hydrolase, TIGR02253 family 1 221 3.1E-88 T 23-10-2018 IPR011950 HAD-superfamily hydrolase, subfamily IA, CTE7 GO:0016787 Reactome: R-HSA-4085001 A0127_01530 d4ece0ecda7ff1558922fb8b5c765974 242 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 108 188 2.5E-14 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A0127_01530 d4ece0ecda7ff1558922fb8b5c765974 242 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 193 4.3E-33 T 23-10-2018 A0127_01530 d4ece0ecda7ff1558922fb8b5c765974 242 SUPERFAMILY SSF56784 1 225 3.68E-49 T 23-10-2018 IPR036412 HAD-like superfamily A0127_01120 e5273915f11ff6bb2c774cd716b81066 477 Pfam PF10117 McrBC 5-methylcytosine restriction system component 63 403 6.5E-68 T 23-10-2018 IPR019292 5-methylcytosine restriction system component A0127_05320 bd62b28f171b47460366e36d7aa74bca 149 Pfam PF04039 Domain related to MnhB subunit of Na+/H+ antiporter 9 135 3.3E-26 T 23-10-2018 IPR007182 Na+/H+ antiporter MnhB subunit-related protein A0127_05900 9c0092f75bbe62b32f0ed0ad30924dc5 357 Gene3D G3DSA:1.10.1580.10 169 252 2.5E-13 T 23-10-2018 IPR023179 GTP-binding protein, orthogonal bundle domain superfamily A0127_05900 9c0092f75bbe62b32f0ed0ad30924dc5 357 Gene3D G3DSA:3.40.50.300 5 162 1.6E-45 T 23-10-2018 A0127_05900 9c0092f75bbe62b32f0ed0ad30924dc5 357 SUPERFAMILY SSF52540 4 168 4.91E-39 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_05900 9c0092f75bbe62b32f0ed0ad30924dc5 357 Pfam PF01926 50S ribosome-binding GTPase 107 162 3.9E-13 T 23-10-2018 IPR006073 GTP binding domain GO:0005525 A0127_02635 8b86a3657eb3e9657e8a7687ef07a263 283 Gene3D G3DSA:3.40.630.30 1 154 1.4E-18 T 23-10-2018 A0127_02635 8b86a3657eb3e9657e8a7687ef07a263 283 SUPERFAMILY SSF55729 2 194 4.25E-23 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase A0127_02635 8b86a3657eb3e9657e8a7687ef07a263 283 Pfam PF13508 Acetyltransferase (GNAT) domain 62 144 2.1E-13 T 23-10-2018 IPR000182 GNAT domain A0127_07870 4f6f4a6b6bb6efc79c044de6e308f251 439 Pfam PF01546 Peptidase family M20/M25/M40 67 434 4.1E-36 T 23-10-2018 IPR002933 Peptidase M20 GO:0016787 A0127_07870 4f6f4a6b6bb6efc79c044de6e308f251 439 Gene3D G3DSA:3.30.70.360 311 352 1.7E-15 T 23-10-2018 A0127_07870 4f6f4a6b6bb6efc79c044de6e308f251 439 SUPERFAMILY SSF53187 2 436 3.55E-59 T 23-10-2018 A0127_07870 4f6f4a6b6bb6efc79c044de6e308f251 439 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 101 138 - T 23-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 A0127_07870 4f6f4a6b6bb6efc79c044de6e308f251 439 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 66 75 - T 23-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 A0127_07870 4f6f4a6b6bb6efc79c044de6e308f251 439 Gene3D G3DSA:3.40.630.10 1 212 2.5E-51 T 23-10-2018 A0127_07870 4f6f4a6b6bb6efc79c044de6e308f251 439 Gene3D G3DSA:3.40.630.10 353 425 1.7E-15 T 23-10-2018 A0127_09760 2356363034f436261fa791d0b9562229 67 Pfam PF02597 ThiS family 10 67 1.1E-9 T 23-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 A0127_09760 2356363034f436261fa791d0b9562229 67 Gene3D G3DSA:3.10.20.30 1 67 2.1E-24 T 23-10-2018 IPR012675 Beta-grasp domain superfamily A0127_09760 2356363034f436261fa791d0b9562229 67 SUPERFAMILY SSF54285 5 67 6.11E-12 T 23-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp A0127_04560 ba3515da747103de170c4041b73c784a 240 Pfam PF10086 Putative membrane peptidase family (DUF2324) 24 127 2.7E-6 T 23-10-2018 IPR011397 Uncharacterised conserved protein UCP033101 A0127_05040 374a9b78a31b7cb5cf8a78785270c5a4 344 Gene3D G3DSA:1.10.3470.10 8 343 4.1E-106 T 23-10-2018 IPR037294 ABC transporter, BtuC-like A0127_05040 374a9b78a31b7cb5cf8a78785270c5a4 344 Pfam PF01032 FecCD transport family 20 339 1.3E-97 T 23-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 A0127_05040 374a9b78a31b7cb5cf8a78785270c5a4 344 SUPERFAMILY SSF81345 6 339 6.8E-87 T 23-10-2018 IPR037294 ABC transporter, BtuC-like A0127_09465 52af01e9d615260d3d779c412c509786 471 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 208 229 1.3E-11 T 23-10-2018 A0127_09465 52af01e9d615260d3d779c412c509786 471 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 76 101 1.3E-11 T 23-10-2018 A0127_09465 52af01e9d615260d3d779c412c509786 471 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 230 256 1.3E-11 T 23-10-2018 A0127_09465 52af01e9d615260d3d779c412c509786 471 Pfam PF00361 Proton-conducting membrane transporter 134 404 3.1E-27 T 23-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A0127_01930 e7f8d52b59bc9ed2a137d28770ccb70f 356 TIGRFAM TIGR00512 salvage_mtnA: S-methyl-5-thioribose-1-phosphate isomerase 15 341 9.4E-129 T 23-10-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 A0127_01930 e7f8d52b59bc9ed2a137d28770ccb70f 356 Gene3D G3DSA:3.40.50.10470 145 343 4.3E-109 T 23-10-2018 A0127_01930 e7f8d52b59bc9ed2a137d28770ccb70f 356 Pfam PF01008 Initiation factor 2 subunit family 55 341 6.9E-85 T 23-10-2018 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 A0127_01930 e7f8d52b59bc9ed2a137d28770ccb70f 356 SUPERFAMILY SSF100950 12 349 9.07E-116 T 23-10-2018 IPR037171 NagB/RpiA transferase-like A0127_01930 e7f8d52b59bc9ed2a137d28770ccb70f 356 Hamap MF_01678 Putative methylthioribose-1-phosphate isomerase [mtnA]. 13 353 40.07 T 23-10-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 A0127_01930 e7f8d52b59bc9ed2a137d28770ccb70f 356 Gene3D G3DSA:1.20.120.420 46 144 4.3E-109 T 23-10-2018 IPR027363 Methylthioribose-1-phosphate isomerase, N-terminal KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 A0127_01930 e7f8d52b59bc9ed2a137d28770ccb70f 356 TIGRFAM TIGR00524 eIF-2B_rel: eIF-2B alpha/beta/delta-related uncharacterized proteins 42 342 7.8E-117 T 23-10-2018 IPR011559 Initiation factor 2B alpha/beta/delta GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 A0127_05640 af289bc65a04c9e45c27d683fa4365a2 1020 PIRSF PIRSF009427 1 1017 0.0 T 23-10-2018 IPR014455 DNA methylase, N-6 adenine-specific, MK1259 type A0127_05640 af289bc65a04c9e45c27d683fa4365a2 1020 Pfam PF06634 Protein of unknown function (DUF1156) 11 57 1.6E-8 T 23-10-2018 IPR009537 Domain of unknown function DUF1156 A0127_05640 af289bc65a04c9e45c27d683fa4365a2 1020 SUPERFAMILY SSF53335 31 701 4.74E-13 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A0127_05640 af289bc65a04c9e45c27d683fa4365a2 1020 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 569 575 - T 23-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 A0127_00855 560a836edd81e205aa25e63e873f9eba 220 SUPERFAMILY SSF55856 124 199 3.53E-24 T 23-10-2018 IPR036400 Cytochrome b5-like heme/steroid binding domain superfamily A0127_00855 560a836edd81e205aa25e63e873f9eba 220 Pfam PF14358 Domain of unknown function (DUF4405) 14 63 1.1E-5 T 23-10-2018 IPR025517 Domain of unknown function DUF4405 A0127_00855 560a836edd81e205aa25e63e873f9eba 220 Pfam PF00173 Cytochrome b5-like Heme/Steroid binding domain 126 196 6.8E-18 T 23-10-2018 IPR001199 Cytochrome b5-like heme/steroid binding domain A0127_00855 560a836edd81e205aa25e63e873f9eba 220 SUPERFAMILY SSF81342 14 71 6.08E-6 T 23-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 A0127_00855 560a836edd81e205aa25e63e873f9eba 220 PRINTS PR00363 Cytochrome B5 signature 184 196 2.2E-5 T 23-10-2018 IPR001199 Cytochrome b5-like heme/steroid binding domain A0127_00855 560a836edd81e205aa25e63e873f9eba 220 PRINTS PR00363 Cytochrome B5 signature 147 157 2.2E-5 T 23-10-2018 IPR001199 Cytochrome b5-like heme/steroid binding domain A0127_00855 560a836edd81e205aa25e63e873f9eba 220 PRINTS PR00363 Cytochrome B5 signature 157 171 2.2E-5 T 23-10-2018 IPR001199 Cytochrome b5-like heme/steroid binding domain A0127_00855 560a836edd81e205aa25e63e873f9eba 220 SMART SM01117 125 197 1.3E-20 T 23-10-2018 IPR001199 Cytochrome b5-like heme/steroid binding domain A0127_00855 560a836edd81e205aa25e63e873f9eba 220 Gene3D G3DSA:3.10.120.10 117 198 4.5E-26 T 23-10-2018 IPR036400 Cytochrome b5-like heme/steroid binding domain superfamily A0127_02500 59ff6fd258e4c4566480911180263b0d 153 Gene3D G3DSA:3.40.50.1010 6 141 2.7E-8 T 23-10-2018 A0127_02500 59ff6fd258e4c4566480911180263b0d 153 Pfam PF01850 PIN domain 6 139 7.1E-10 T 23-10-2018 IPR002716 PIN domain A0127_02500 59ff6fd258e4c4566480911180263b0d 153 SUPERFAMILY SSF88723 5 144 1.33E-15 T 23-10-2018 IPR029060 PIN-like domain superfamily A0127_06255 6db28ac2541c3de0d068a2c083ac99d7 904 Pfam PF00493 MCM2/3/5 family 378 713 1.8E-8 T 23-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 A0127_06255 6db28ac2541c3de0d068a2c083ac99d7 904 Gene3D G3DSA:3.40.50.300 371 720 3.8E-23 T 23-10-2018 A0127_06255 6db28ac2541c3de0d068a2c083ac99d7 904 SUPERFAMILY SSF52540 429 583 9.52E-11 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_06670 ab06de4838457df4186720553afacec6 478 SUPERFAMILY SSF53649 15 462 9.29E-40 T 23-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 A0127_06670 ab06de4838457df4186720553afacec6 478 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 17 423 3.5E-63 T 23-10-2018 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 A0127_06670 ab06de4838457df4186720553afacec6 478 Gene3D G3DSA:3.40.720.10 4 307 9.3E-51 T 23-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 A0127_07150 ce284f1c4952fb00332007e59479f8b8 334 Pfam PF17179 4Fe-4S dicluster domain 229 320 2.9E-24 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A0127_07150 ce284f1c4952fb00332007e59479f8b8 334 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 229 240 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A0127_07150 ce284f1c4952fb00332007e59479f8b8 334 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 306 317 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A0127_07150 ce284f1c4952fb00332007e59479f8b8 334 SUPERFAMILY SSF46548 225 331 2.88E-12 T 23-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 A0127_03100 fa303e23205071161d02036b3a829d89 656 Pfam PF13086 AAA domain 176 424 5.0E-55 T 23-10-2018 A0127_03100 fa303e23205071161d02036b3a829d89 656 TIGRFAM TIGR00376 TIGR00376: putative DNA helicase 20 653 2.9E-249 T 23-10-2018 IPR004483 Helicase SMUBP-2/Hcs1-like GO:0003677|GO:0005524 A0127_03100 fa303e23205071161d02036b3a829d89 656 Pfam PF13087 AAA domain 430 631 3.0E-57 T 23-10-2018 A0127_03100 fa303e23205071161d02036b3a829d89 656 Gene3D G3DSA:3.40.50.300 453 655 7.8E-62 T 23-10-2018 A0127_03100 fa303e23205071161d02036b3a829d89 656 SUPERFAMILY SSF52540 170 642 1.87E-65 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_06230 980f65e1e8fac9009e62b2dc2067b47f 374 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 5 364 4.9E-38 T 23-10-2018 IPR002823 Protein of unknown function DUF112, transmembrane A0127_04160 94502c1a788b43a455e56dc9a6b93b8c 320 TIGRFAM TIGR00144 beta_RFAP_syn: beta-ribofuranosylaminobenzene 5'-phosphate synthase family 7 317 4.8E-39 T 23-10-2018 IPR004422 GHMP kinase group 1 KEGG: 00790+2.4.2.54|MetaCyc: PWY-6148 A0127_04160 94502c1a788b43a455e56dc9a6b93b8c 320 Gene3D G3DSA:3.30.230.10 6 140 3.3E-6 T 23-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup A0127_04160 94502c1a788b43a455e56dc9a6b93b8c 320 PIRSF PIRSF004884 2 320 1.0E-72 T 23-10-2018 IPR004422 GHMP kinase group 1 KEGG: 00790+2.4.2.54|MetaCyc: PWY-6148 A0127_04160 94502c1a788b43a455e56dc9a6b93b8c 320 SUPERFAMILY SSF54211 6 142 1.97E-13 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A0127_05350 38be29e9794a1cdd41489f405ddfdc14 426 Pfam PF00374 Nickel-dependent hydrogenase 47 115 3.2E-13 T 23-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 A0127_05350 38be29e9794a1cdd41489f405ddfdc14 426 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 122 381 3.3E-57 T 23-10-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A0127_05350 38be29e9794a1cdd41489f405ddfdc14 426 Gene3D G3DSA:1.10.645.20 9 381 2.0E-122 T 23-10-2018 IPR038290 NADH-quinone oxidoreductase, subunit D superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A0127_05350 38be29e9794a1cdd41489f405ddfdc14 426 SUPERFAMILY SSF56762 18 381 7.33E-105 T 23-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A0127_08220 bdad02beda28de2f3cb573c990b50d9f 181 Pfam PF03351 DOMON domain 38 158 2.9E-28 T 23-10-2018 IPR005018 DOMON domain A0127_08220 bdad02beda28de2f3cb573c990b50d9f 181 SMART SM00664 62 158 1.1E-17 T 23-10-2018 IPR005018 DOMON domain A0127_08220 bdad02beda28de2f3cb573c990b50d9f 181 SUPERFAMILY SSF49344 56 171 9.02E-10 T 23-10-2018 A0127_10280 bc0fff1bf6a82f12966cdd3550d92919 196 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 135 144 4.9E-24 T 23-10-2018 A0127_10280 bc0fff1bf6a82f12966cdd3550d92919 196 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 173 196 4.9E-24 T 23-10-2018 A0127_10280 bc0fff1bf6a82f12966cdd3550d92919 196 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 4.9E-24 T 23-10-2018 A0127_10280 bc0fff1bf6a82f12966cdd3550d92919 196 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 37 52 4.9E-24 T 23-10-2018 A0127_10280 bc0fff1bf6a82f12966cdd3550d92919 196 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 38 48 - T 23-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 A0127_10280 bc0fff1bf6a82f12966cdd3550d92919 196 SUPERFAMILY SSF51905 2 181 6.2E-30 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A0127_10280 bc0fff1bf6a82f12966cdd3550d92919 196 Gene3D G3DSA:3.50.50.60 144 181 1.3E-46 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A0127_10280 bc0fff1bf6a82f12966cdd3550d92919 196 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 2.7E-11 T 23-10-2018 A0127_10280 bc0fff1bf6a82f12966cdd3550d92919 196 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 132 150 2.7E-11 T 23-10-2018 A0127_10280 bc0fff1bf6a82f12966cdd3550d92919 196 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 173 191 2.7E-11 T 23-10-2018 A0127_10280 bc0fff1bf6a82f12966cdd3550d92919 196 Gene3D G3DSA:3.50.50.60 8 143 1.3E-46 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A0127_10280 bc0fff1bf6a82f12966cdd3550d92919 196 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 181 6.5E-27 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A0127_06130 02bb68916f7b3efbadd70ae4fbc5787f 233 Pfam PF00175 Oxidoreductase NAD-binding domain 94 183 2.4E-8 T 23-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 A0127_06130 02bb68916f7b3efbadd70ae4fbc5787f 233 SUPERFAMILY SSF63380 3 85 8.06E-18 T 23-10-2018 IPR017938 Riboflavin synthase-like beta-barrel A0127_06130 02bb68916f7b3efbadd70ae4fbc5787f 233 Gene3D G3DSA:3.40.50.80 85 196 2.5E-28 T 23-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A0127_06130 02bb68916f7b3efbadd70ae4fbc5787f 233 PRINTS PR00409 Phthalate dioxygenase reductase family signature 118 127 1.6E-5 T 23-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 A0127_06130 02bb68916f7b3efbadd70ae4fbc5787f 233 PRINTS PR00409 Phthalate dioxygenase reductase family signature 170 178 1.6E-5 T 23-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 A0127_06130 02bb68916f7b3efbadd70ae4fbc5787f 233 PRINTS PR00409 Phthalate dioxygenase reductase family signature 93 112 1.6E-5 T 23-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 A0127_06130 02bb68916f7b3efbadd70ae4fbc5787f 233 SUPERFAMILY SSF52343 80 229 2.88E-33 T 23-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A0127_06130 02bb68916f7b3efbadd70ae4fbc5787f 233 Gene3D G3DSA:2.40.30.10 3 84 1.3E-11 T 23-10-2018 A0127_06130 02bb68916f7b3efbadd70ae4fbc5787f 233 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 197 229 2.2E-10 T 23-10-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain A0127_06130 02bb68916f7b3efbadd70ae4fbc5787f 233 PIRSF PIRSF006816 1 232 1.2E-75 T 23-10-2018 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 A0127_06130 02bb68916f7b3efbadd70ae4fbc5787f 233 Hamap MF_01211 Dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit [pyrK]. 2 231 33.558 T 23-10-2018 IPR023455 Dihydroorotate dehydrogenase electron transfer subunit A0127_03065 48031403f66c8f1b90991559dba91326 426 Gene3D G3DSA:1.10.287.660 131 243 7.3E-39 T 23-10-2018 IPR029012 Helix hairpin bin domain superfamily A0127_03065 48031403f66c8f1b90991559dba91326 426 SMART SM00931 130 182 1.5E-27 T 23-10-2018 IPR012976 NOSIC A0127_03065 48031403f66c8f1b90991559dba91326 426 SUPERFAMILY SSF89124 126 366 2.09E-81 T 23-10-2018 IPR036070 Nop domain superfamily A0127_03065 48031403f66c8f1b90991559dba91326 426 Pfam PF01798 snoRNA binding domain, fibrillarin 138 363 3.7E-73 T 23-10-2018 IPR002687 Nop domain A0127_03065 48031403f66c8f1b90991559dba91326 426 Gene3D G3DSA:1.10.150.460 161 212 7.3E-39 T 23-10-2018 A0127_03065 48031403f66c8f1b90991559dba91326 426 Gene3D G3DSA:3.30.420.220 1 125 5.7E-47 T 23-10-2018 A0127_03065 48031403f66c8f1b90991559dba91326 426 Gene3D G3DSA:1.10.246.90 244 368 4.7E-53 T 23-10-2018 A0127_05460 90095a154c70fb5240140b2389439a7e 306 Gene3D G3DSA:1.10.10.10 153 199 6.3E-10 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A0127_05460 90095a154c70fb5240140b2389439a7e 306 Pfam PF13412 Winged helix-turn-helix DNA-binding 154 195 3.4E-9 T 23-10-2018 A0127_05460 90095a154c70fb5240140b2389439a7e 306 SUPERFAMILY SSF46785 151 196 6.71E-7 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A0127_01645 d2d73eb6cdedf6b069cfee0f53af8b12 504 Gene3D G3DSA:3.40.50.300 248 492 3.2E-41 T 23-10-2018 A0127_01645 d2d73eb6cdedf6b069cfee0f53af8b12 504 SUPERFAMILY SSF52540 237 485 3.12E-43 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_01645 d2d73eb6cdedf6b069cfee0f53af8b12 504 Pfam PF00005 ABC transporter 15 165 2.2E-27 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A0127_01645 d2d73eb6cdedf6b069cfee0f53af8b12 504 Pfam PF00005 ABC transporter 270 426 6.6E-16 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A0127_01645 d2d73eb6cdedf6b069cfee0f53af8b12 504 SUPERFAMILY SSF52540 2 224 6.85E-58 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_01645 d2d73eb6cdedf6b069cfee0f53af8b12 504 SMART SM00382 24 213 1.3E-16 T 23-10-2018 IPR003593 AAA+ ATPase domain A0127_01645 d2d73eb6cdedf6b069cfee0f53af8b12 504 ProSitePatterns PS00211 ABC transporters family signature. 399 413 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A0127_01645 d2d73eb6cdedf6b069cfee0f53af8b12 504 Gene3D G3DSA:3.40.50.300 1 237 6.7E-56 T 23-10-2018 A0127_10015 6d35b5bbcfd68ae6a3ae1bdd42a0bf85 59 SUPERFAMILY SSF47113 6 59 5.7E-7 T 23-10-2018 IPR009072 Histone-fold GO:0046982 A0127_07185 d3df95bc78f0ff4ebb9fd75bb4af1704 237 Gene3D G3DSA:3.40.50.11570 10 225 1.5E-57 T 23-10-2018 A0127_07185 d3df95bc78f0ff4ebb9fd75bb4af1704 237 Pfam PF03192 Pyrococcus protein of unknown function, DUF257 16 221 6.7E-73 T 23-10-2018 IPR005489 Protein of unknown function DUF257 A0127_04950 a30ce8b0cabfcdff9ad5406b41428665 80 SMART SM00966 6 48 1.4E-4 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 A0127_04950 a30ce8b0cabfcdff9ad5406b41428665 80 SUPERFAMILY SSF89447 1 52 9.16E-9 T 23-10-2018 IPR037914 SpoVT-AbrB domain superfamily A0127_08560 0ba4b6a8d502ff1e9ab486d8cf10ea08 137 TIGRFAM TIGR03161 ribazole_CobZ: alpha-ribazole phosphatase CobZ 8 134 3.6E-55 T 23-10-2018 IPR017577 Alpha-ribazole phosphatase, CobZ A0127_08560 0ba4b6a8d502ff1e9ab486d8cf10ea08 137 SUPERFAMILY SSF101307 6 134 5.62E-35 T 23-10-2018 IPR036681 PgpA-like superfamily GO:0006629|GO:0008962 A0127_08560 0ba4b6a8d502ff1e9ab486d8cf10ea08 137 Gene3D G3DSA:1.10.3760.10 2 136 2.7E-12 T 23-10-2018 A0127_08560 0ba4b6a8d502ff1e9ab486d8cf10ea08 137 Pfam PF04608 Phosphatidylglycerophosphatase A 15 133 5.4E-9 T 23-10-2018 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 A0127_04015 53dad138329ba1ecfe43b37c8d68b62c 63 Pfam PF01402 Ribbon-helix-helix protein, copG family 7 45 2.1E-8 T 23-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 A0127_04015 53dad138329ba1ecfe43b37c8d68b62c 63 SUPERFAMILY SSF47598 4 46 4.78E-13 T 23-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 A0127_04015 53dad138329ba1ecfe43b37c8d68b62c 63 Gene3D G3DSA:1.10.1220.10 11 46 8.8E-11 T 23-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 A0127_02360 32b0825ec8e3f3d52829986434d784cd 217 Gene3D G3DSA:1.10.150.520 18 89 1.9E-50 T 23-10-2018 A0127_02360 32b0825ec8e3f3d52829986434d784cd 217 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 101 114 4.1E-17 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A0127_02360 32b0825ec8e3f3d52829986434d784cd 217 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 4 15 4.1E-17 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A0127_02360 32b0825ec8e3f3d52829986434d784cd 217 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 131 147 4.1E-17 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A0127_02360 32b0825ec8e3f3d52829986434d784cd 217 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 149 169 4.1E-17 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A0127_02360 32b0825ec8e3f3d52829986434d784cd 217 ProSitePatterns PS01228 Hypothetical cof family signature 1. 6 17 - T 23-10-2018 A0127_02360 32b0825ec8e3f3d52829986434d784cd 217 TIGRFAM TIGR02253 CTE7: HAD hydrolase, TIGR02253 family 4 209 9.2E-54 T 23-10-2018 IPR011950 HAD-superfamily hydrolase, subfamily IA, CTE7 GO:0016787 Reactome: R-HSA-4085001 A0127_02360 32b0825ec8e3f3d52829986434d784cd 217 Pfam PF13419 Haloacid dehalogenase-like hydrolase 7 188 1.3E-33 T 23-10-2018 A0127_02360 32b0825ec8e3f3d52829986434d784cd 217 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 81 188 2.7E-14 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A0127_02360 32b0825ec8e3f3d52829986434d784cd 217 SUPERFAMILY SSF56784 4 213 6.17E-51 T 23-10-2018 IPR036412 HAD-like superfamily A0127_02360 32b0825ec8e3f3d52829986434d784cd 217 Gene3D G3DSA:3.40.50.1000 5 209 1.9E-50 T 23-10-2018 IPR023214 HAD superfamily A0127_02360 32b0825ec8e3f3d52829986434d784cd 217 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 101 182 3.5E-13 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A0127_03770 da69e109a7e24a8981d58f7a32905a89 344 TIGRFAM TIGR00638 Mop: molybdenum-pterin binding domain 279 343 3.2E-16 T 23-10-2018 IPR004606 Molybdenum-pterin binding GO:0015689 A0127_03770 da69e109a7e24a8981d58f7a32905a89 344 Gene3D G3DSA:2.40.50.100 268 339 2.4E-26 T 23-10-2018 A0127_03770 da69e109a7e24a8981d58f7a32905a89 344 Gene3D G3DSA:2.40.50.140 248 343 2.4E-26 T 23-10-2018 A0127_03770 da69e109a7e24a8981d58f7a32905a89 344 SMART SM00382 25 243 7.0E-13 T 23-10-2018 IPR003593 AAA+ ATPase domain A0127_03770 da69e109a7e24a8981d58f7a32905a89 344 Pfam PF03459 TOBE domain 281 343 2.8E-16 T 23-10-2018 IPR005116 Transport-associated OB, type 1 A0127_03770 da69e109a7e24a8981d58f7a32905a89 344 Pfam PF00005 ABC transporter 16 159 7.9E-34 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A0127_03770 da69e109a7e24a8981d58f7a32905a89 344 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A0127_03770 da69e109a7e24a8981d58f7a32905a89 344 Gene3D G3DSA:3.40.50.300 1 237 1.9E-72 T 23-10-2018 A0127_03770 da69e109a7e24a8981d58f7a32905a89 344 SUPERFAMILY SSF50331 243 344 3.93E-22 T 23-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal A0127_03770 da69e109a7e24a8981d58f7a32905a89 344 SUPERFAMILY SSF52540 1 237 8.78E-79 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_00740 f671bd4b89212fa74c2c8e950b6c41d0 145 Gene3D G3DSA:2.40.50.180 24 136 2.7E-42 T 23-10-2018 A0127_00740 f671bd4b89212fa74c2c8e950b6c41d0 145 SUPERFAMILY SSF50341 2 143 1.57E-38 T 23-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 A0127_00740 f671bd4b89212fa74c2c8e950b6c41d0 145 Gene3D G3DSA:2.30.30.40 7 135 2.7E-42 T 23-10-2018 A0127_00740 f671bd4b89212fa74c2c8e950b6c41d0 145 SMART SM00260 1 141 1.0E-46 T 23-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 A0127_00740 f671bd4b89212fa74c2c8e950b6c41d0 145 Pfam PF01584 CheW-like domain 5 143 1.5E-36 T 23-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 A0127_08680 4d400bec7822f13eac85751c27bc6bc2 386 Pfam PF04412 Protein of unknown function (DUF521) 1 383 1.4E-148 T 23-10-2018 IPR007506 Aconitase X catalytic domain, putative A0127_06540 73e26284a47e07bf10845d1499015517 394 SUPERFAMILY SSF51971 1 390 4.59E-41 T 23-10-2018 A0127_06540 73e26284a47e07bf10845d1499015517 394 Pfam PF13450 NAD(P)-binding Rossmann-like domain 6 73 1.2E-15 T 23-10-2018 A0127_06540 73e26284a47e07bf10845d1499015517 394 SUPERFAMILY SSF54373 265 333 4.32E-19 T 23-10-2018 A0127_06540 73e26284a47e07bf10845d1499015517 394 Pfam PF03275 UDP-galactopyranose mutase 155 371 3.4E-64 T 23-10-2018 IPR015899 UDP-galactopyranose mutase, C-terminal GO:0008767 KEGG: 00052+5.4.99.9|KEGG: 00520+5.4.99.9|MetaCyc: PWY-6397|MetaCyc: PWY-7328|MetaCyc: PWY-7622 A0127_06540 73e26284a47e07bf10845d1499015517 394 Gene3D G3DSA:3.40.50.720 281 393 1.1E-13 T 23-10-2018 A0127_06540 73e26284a47e07bf10845d1499015517 394 Gene3D G3DSA:3.40.50.720 168 280 2.3E-26 T 23-10-2018 A0127_06540 73e26284a47e07bf10845d1499015517 394 TIGRFAM TIGR00031 UDP-GALP_mutase: UDP-galactopyranose mutase 1 389 1.7E-126 T 23-10-2018 IPR004379 UDP-galactopyranose mutase GO:0008767 KEGG: 00052+5.4.99.9|KEGG: 00520+5.4.99.9|MetaCyc: PWY-6397|MetaCyc: PWY-7328|MetaCyc: PWY-7622 A0127_06540 73e26284a47e07bf10845d1499015517 394 Gene3D G3DSA:3.40.50.720 1 90 7.4E-31 T 23-10-2018 A0127_01485 9d6f61c4a36d1ab6d54a8d9c9a7f2c42 473 Gene3D G3DSA:3.30.2290.10 1 196 2.6E-24 T 23-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal A0127_01485 9d6f61c4a36d1ab6d54a8d9c9a7f2c42 473 PIRSF PIRSF004919 1 472 5.5E-148 T 23-10-2018 IPR025502 TldD A0127_01485 9d6f61c4a36d1ab6d54a8d9c9a7f2c42 473 SUPERFAMILY SSF111283 1 468 2.09E-104 T 23-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 A0127_01485 9d6f61c4a36d1ab6d54a8d9c9a7f2c42 473 Pfam PF01523 Putative modulator of DNA gyrase 19 325 1.0E-54 T 23-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 A0127_00335 f6d9301069a5514dee344828cbeb7619 272 Pfam PF06508 Queuosine biosynthesis protein QueC 23 82 4.9E-8 T 23-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 A0127_00335 f6d9301069a5514dee344828cbeb7619 272 SUPERFAMILY SSF52402 14 186 1.59E-30 T 23-10-2018 A0127_00335 f6d9301069a5514dee344828cbeb7619 272 PIRSF PIRSF036670 1 261 3.5E-125 T 23-10-2018 IPR012122 ATPase, PP-loop, MJ1016-related A0127_00335 f6d9301069a5514dee344828cbeb7619 272 Gene3D G3DSA:3.40.50.620 1 259 5.1E-27 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A0127_02095 b2623b058748546976ee52ff2ad41597 110 Pfam PF11419 Protein of unknown function (DUF3194) 15 97 4.7E-28 T 23-10-2018 IPR024502 Protein of unknown function DUF3194 A0127_02095 b2623b058748546976ee52ff2ad41597 110 Gene3D G3DSA:3.30.300.100 1 110 1.2E-39 T 23-10-2018 IPR035954 MTH677-like superfamily A0127_07910 4c3c703db5ef0e053cc34389cae418c0 221 ProDom PD016938 P COMPONENT RIBONUCLEASE RNASE HYDROLASE PROCESSING TRNA SUBUNIT SIMILAR P/RNASE 117 209 3.0E-38 T 23-10-2018 A0127_07910 4c3c703db5ef0e053cc34389cae418c0 221 Hamap MF_00756 Ribonuclease P protein component 3 [rnp3]. 11 221 22.947 T 23-10-2018 IPR023539 Ribonuclease P, protein component 3, archaeal GO:0001682|GO:0004526 A0127_07910 4c3c703db5ef0e053cc34389cae418c0 221 Pfam PF01876 RNase P subunit p30 21 210 1.2E-35 T 23-10-2018 IPR002738 RNase P subunit p30 GO:0004540|GO:0008033 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 A0127_07910 4c3c703db5ef0e053cc34389cae418c0 221 Gene3D G3DSA:3.20.20.140 1 220 2.2E-109 T 23-10-2018 A0127_07910 4c3c703db5ef0e053cc34389cae418c0 221 SUPERFAMILY SSF89550 13 217 9.81E-34 T 23-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 A0127_04905 bdfc38f31cda3d6d78422aed36d0031e 215 Pfam PF01865 Protein of unknown function DUF47 7 211 1.4E-42 T 23-10-2018 IPR018445 Putative phosphate transport regulator A0127_04905 bdfc38f31cda3d6d78422aed36d0031e 215 Gene3D G3DSA:1.20.58.220 2 212 8.8E-48 T 23-10-2018 IPR038078 PhoU-like domain superfamily A0127_04905 bdfc38f31cda3d6d78422aed36d0031e 215 TIGRFAM TIGR00153 TIGR00153: TIGR00153 family protein 16 214 1.5E-40 T 23-10-2018 IPR002727 Protein of unknown function DUF47 A0127_04905 bdfc38f31cda3d6d78422aed36d0031e 215 SUPERFAMILY SSF109755 10 207 2.14E-9 T 23-10-2018 A0127_07245 73e3b0fe20bc4ba76191ec6e173764ed 667 Pfam PF01496 V-type ATPase 116kDa subunit family 193 440 1.7E-23 T 23-10-2018 IPR002490 V-type ATPase, V0 complex, 116kDa subunit family GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A0127_07245 73e3b0fe20bc4ba76191ec6e173764ed 667 Pfam PF01496 V-type ATPase 116kDa subunit family 564 651 2.9E-10 T 23-10-2018 IPR002490 V-type ATPase, V0 complex, 116kDa subunit family GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A0127_07245 73e3b0fe20bc4ba76191ec6e173764ed 667 Gene3D G3DSA:3.30.70.2170 7 309 4.8E-25 T 23-10-2018 A0127_07245 73e3b0fe20bc4ba76191ec6e173764ed 667 Gene3D G3DSA:3.30.70.2750 149 224 4.8E-25 T 23-10-2018 A0127_07245 73e3b0fe20bc4ba76191ec6e173764ed 667 Gene3D G3DSA:1.20.1460.20 47 290 4.8E-25 T 23-10-2018 A0127_02805 bdd51be51951d105fcf03ec432c2d20d 302 Gene3D G3DSA:3.40.50.10800 88 300 1.8E-123 T 23-10-2018 A0127_02805 bdd51be51951d105fcf03ec432c2d20d 302 Gene3D G3DSA:3.40.50.10800 173 257 1.8E-123 T 23-10-2018 A0127_02805 bdd51be51951d105fcf03ec432c2d20d 302 SUPERFAMILY SSF142754 5 301 1.03E-115 T 23-10-2018 IPR036094 Quinolinate synthetase A superfamily GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 A0127_02805 bdd51be51951d105fcf03ec432c2d20d 302 Hamap MF_00568 Quinolinate synthase A [nadA]. 4 301 45.666 T 23-10-2018 IPR023066 Quinolinate synthase A, type 2 GO:0016765 MetaCyc: PWY-5316|MetaCyc: PWY-7342 A0127_02805 bdd51be51951d105fcf03ec432c2d20d 302 TIGRFAM TIGR00550 nadA: quinolinate synthetase complex, A subunit 2 302 9.9E-115 T 23-10-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 A0127_02805 bdd51be51951d105fcf03ec432c2d20d 302 Pfam PF02445 Quinolinate synthetase A protein 8 300 2.7E-112 T 23-10-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 A0127_02805 bdd51be51951d105fcf03ec432c2d20d 302 Gene3D G3DSA:3.40.50.10800 8 282 1.8E-123 T 23-10-2018 A0127_09185 87b5a67aedec176fa7cd9938dd7ed076 562 Pfam PF01642 Methylmalonyl-CoA mutase 39 554 1.9E-240 T 23-10-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 A0127_09185 87b5a67aedec176fa7cd9938dd7ed076 562 TIGRFAM TIGR00641 acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain 37 560 1.6E-289 T 23-10-2018 IPR006098 Methylmalonyl-CoA mutase, alpha chain, catalytic GO:0004494|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 A0127_09185 87b5a67aedec176fa7cd9938dd7ed076 562 SUPERFAMILY SSF51703 10 556 2.35E-230 T 23-10-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 A0127_09185 87b5a67aedec176fa7cd9938dd7ed076 562 Gene3D G3DSA:3.20.20.240 1 562 3.9E-269 T 23-10-2018 A0127_04460 3ae3c56a32dfaea7204064a6ce5d21da 455 PIRSF PIRSF004919 1 455 1.3E-161 T 23-10-2018 IPR025502 TldD A0127_04460 3ae3c56a32dfaea7204064a6ce5d21da 455 Pfam PF01523 Putative modulator of DNA gyrase 21 309 1.4E-64 T 23-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 A0127_04460 3ae3c56a32dfaea7204064a6ce5d21da 455 SUPERFAMILY SSF111283 2 449 3.66E-114 T 23-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 A0127_04460 3ae3c56a32dfaea7204064a6ce5d21da 455 Gene3D G3DSA:3.30.2290.10 1 193 5.7E-19 T 23-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal A0127_04285 43280c329692d45c6c80c17e8c7480b3 168 Pfam PF02778 tRNA intron endonuclease, N-terminal domain 3 67 2.6E-21 T 23-10-2018 IPR006678 tRNA intron endonuclease, N-terminal GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803|Reactome: R-HSA-6784531 A0127_04285 43280c329692d45c6c80c17e8c7480b3 168 SUPERFAMILY SSF55267 2 73 1.94E-19 T 23-10-2018 IPR036740 tRNA intron endonuclease, N-terminal domain superfamily GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803 A0127_04285 43280c329692d45c6c80c17e8c7480b3 168 Gene3D G3DSA:3.40.1350.10 76 168 1.7E-34 T 23-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 A0127_04285 43280c329692d45c6c80c17e8c7480b3 168 PIRSF PIRSF005285 5 168 7.0E-69 T 23-10-2018 IPR016442 tRNA-splicing endonuclease, archaeal short subfamily MetaCyc: PWY-6689|MetaCyc: PWY-7803 A0127_04285 43280c329692d45c6c80c17e8c7480b3 168 Hamap MF_01833 tRNA-splicing endonuclease [endA]. 2 168 34.119 T 23-10-2018 IPR016442 tRNA-splicing endonuclease, archaeal short subfamily MetaCyc: PWY-6689|MetaCyc: PWY-7803 A0127_04285 43280c329692d45c6c80c17e8c7480b3 168 SUPERFAMILY SSF53032 77 166 3.4E-31 T 23-10-2018 IPR036167 tRNA intron endonuclease, catalytic domain-like superfamily GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803|Reactome: R-HSA-6784531 A0127_04285 43280c329692d45c6c80c17e8c7480b3 168 TIGRFAM TIGR00324 endA: tRNA-intron lyase 6 166 5.5E-41 T 23-10-2018 IPR006676 tRNA-splicing endonuclease GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803|Reactome: R-HSA-6784531 A0127_04285 43280c329692d45c6c80c17e8c7480b3 168 Gene3D G3DSA:3.40.1170.20 5 70 5.2E-18 T 23-10-2018 A0127_04285 43280c329692d45c6c80c17e8c7480b3 168 Pfam PF01974 tRNA intron endonuclease, catalytic C-terminal domain 77 160 3.4E-33 T 23-10-2018 IPR006677 tRNA intron endonuclease, catalytic domain-like GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803|Reactome: R-HSA-6784531 A0127_01915 3a7bd17c9351ef056f05fea362ab9954 182 Pfam PF12840 Helix-turn-helix domain 15 70 3.9E-11 T 23-10-2018 A0127_01915 3a7bd17c9351ef056f05fea362ab9954 182 SUPERFAMILY SSF46785 7 134 9.25E-21 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A0127_01915 3a7bd17c9351ef056f05fea362ab9954 182 SMART SM00418 15 99 3.6E-4 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A0127_01915 3a7bd17c9351ef056f05fea362ab9954 182 Gene3D G3DSA:1.10.10.10 8 92 6.4E-17 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A0127_02825 bfdd5230af1ecc2a83bd85dbadb0a242 249 SMART SM00849 37 215 1.5E-14 T 23-10-2018 IPR001279 Metallo-beta-lactamase A0127_02825 bfdd5230af1ecc2a83bd85dbadb0a242 249 Pfam PF12706 Beta-lactamase superfamily domain 64 216 1.2E-16 T 23-10-2018 IPR001279 Metallo-beta-lactamase A0127_02825 bfdd5230af1ecc2a83bd85dbadb0a242 249 SUPERFAMILY SSF56281 1 247 2.36E-41 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A0127_02825 bfdd5230af1ecc2a83bd85dbadb0a242 249 Gene3D G3DSA:3.60.15.10 1 249 1.5E-49 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A0127_03870 dca7cc7876738c664c7944bc3e0fe162 239 TIGRFAM TIGR01487 Pglycolate_arch: phosphoglycolate phosphatase, TA0175-type 3 222 2.3E-76 T 23-10-2018 A0127_03870 dca7cc7876738c664c7944bc3e0fe162 239 Hamap MF_01419 Phosphoglycolate phosphatase. 3 229 32.114 T 23-10-2018 IPR006382 Phosphoglycolate phosphatase GO:0000287|GO:0008967|GO:0016311 KEGG: 00630+3.1.3.18|MetaCyc: PWY-181 A0127_03870 dca7cc7876738c664c7944bc3e0fe162 239 Pfam PF08282 haloacid dehalogenase-like hydrolase 140 223 4.8E-18 T 23-10-2018 A0127_03870 dca7cc7876738c664c7944bc3e0fe162 239 Pfam PF08282 haloacid dehalogenase-like hydrolase 6 89 5.8E-7 T 23-10-2018 A0127_03870 dca7cc7876738c664c7944bc3e0fe162 239 TIGRFAM TIGR01482 SPP-subfamily: sucrose-phosphate phosphatase subfamily 6 232 7.4E-73 T 23-10-2018 A0127_03870 dca7cc7876738c664c7944bc3e0fe162 239 Gene3D G3DSA:3.90.1070.10 86 153 1.3E-71 T 23-10-2018 A0127_03870 dca7cc7876738c664c7944bc3e0fe162 239 Gene3D G3DSA:3.40.50.1000 4 223 1.3E-71 T 23-10-2018 IPR023214 HAD superfamily A0127_03870 dca7cc7876738c664c7944bc3e0fe162 239 SUPERFAMILY SSF56784 1 228 2.97E-41 T 23-10-2018 IPR036412 HAD-like superfamily A0127_01495 c67535fdbfbd15e95648d64c726674fa 400 Gene3D G3DSA:1.20.1250.20 5 380 2.6E-27 T 23-10-2018 A0127_01495 c67535fdbfbd15e95648d64c726674fa 400 SUPERFAMILY SSF103473 11 380 1.57E-29 T 23-10-2018 IPR036259 MFS transporter superfamily A0127_01495 c67535fdbfbd15e95648d64c726674fa 400 Pfam PF07690 Major Facilitator Superfamily 15 349 2.0E-17 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A0127_07650 de6477e0ab2f923f1c22868c482d791b 149 Pfam PF00416 Ribosomal protein S13/S18 10 137 1.0E-42 T 23-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_07650 de6477e0ab2f923f1c22868c482d791b 149 ProSitePatterns PS00646 Ribosomal protein S13 signature. 117 130 - T 23-10-2018 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_07650 de6477e0ab2f923f1c22868c482d791b 149 PIRSF PIRSF002134 1 149 1.4E-42 T 23-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_07650 de6477e0ab2f923f1c22868c482d791b 149 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 8 148 25.639 T 23-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_07650 de6477e0ab2f923f1c22868c482d791b 149 Gene3D G3DSA:1.10.8.50 1 76 1.5E-27 T 23-10-2018 A0127_07650 de6477e0ab2f923f1c22868c482d791b 149 Gene3D G3DSA:4.10.910.10 88 138 3.1E-21 T 23-10-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_07650 de6477e0ab2f923f1c22868c482d791b 149 SUPERFAMILY SSF46946 9 148 3.53E-36 T 23-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 A0127_07650 de6477e0ab2f923f1c22868c482d791b 149 TIGRFAM TIGR03629 uS13_arch: ribosomal protein uS13 4 148 1.9E-62 T 23-10-2018 IPR019977 Ribosomal protein S13, archaeal GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 A0127_09845 b1ef004415bb46d234c6e198abe73f88 129 PIRSF PIRSF014543 1 124 8.2E-51 T 23-10-2018 IPR016621 Uncharacterised conserved protein UCP014543 A0127_09845 b1ef004415bb46d234c6e198abe73f88 129 Pfam PF12646 Domain of unknown function (DUF3783) 56 111 1.4E-13 T 23-10-2018 IPR016621 Uncharacterised conserved protein UCP014543 A0127_06100 e82dbdcf70c83886cd454ada14313318 1147 SUPERFAMILY SSF49344 24 222 5.89E-12 T 23-10-2018 A0127_06100 e82dbdcf70c83886cd454ada14313318 1147 Pfam PF07705 CARDB 444 540 3.8E-18 T 23-10-2018 IPR011635 CARDB domain A0127_06100 e82dbdcf70c83886cd454ada14313318 1147 SUPERFAMILY SSF49344 940 1097 1.45E-10 T 23-10-2018 A0127_06100 e82dbdcf70c83886cd454ada14313318 1147 SUPERFAMILY SSF49344 233 407 3.92E-11 T 23-10-2018 A0127_06100 e82dbdcf70c83886cd454ada14313318 1147 Gene3D G3DSA:2.60.40.10 431 548 1.8E-32 T 23-10-2018 IPR013783 Immunoglobulin-like fold A0127_06100 e82dbdcf70c83886cd454ada14313318 1147 SUPERFAMILY SSF49344 593 773 4.12E-5 T 23-10-2018 A0127_06100 e82dbdcf70c83886cd454ada14313318 1147 Gene3D G3DSA:2.60.40.1190 235 430 1.0E-5 T 23-10-2018 A0127_06100 e82dbdcf70c83886cd454ada14313318 1147 Gene3D G3DSA:2.60.40.1190 23 230 2.3E-5 T 23-10-2018 A0127_03230 e28322e8b5df6eb22c65ad3e8ccd65e5 147 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 3 58 6.6E-18 T 23-10-2018 IPR022687 DTXR-type HTH domain GO:0003677 A0127_03230 e28322e8b5df6eb22c65ad3e8ccd65e5 147 SUPERFAMILY SSF46785 4 63 3.71E-16 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A0127_03230 e28322e8b5df6eb22c65ad3e8ccd65e5 147 Gene3D G3DSA:1.10.60.10 69 123 3.0E-20 T 23-10-2018 IPR036421 Iron dependent repressor, metal binding and dimerisation domain superfamily GO:0046914|GO:0046983 A0127_03230 e28322e8b5df6eb22c65ad3e8ccd65e5 147 Gene3D G3DSA:1.10.10.10 3 68 1.3E-25 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A0127_03230 e28322e8b5df6eb22c65ad3e8ccd65e5 147 SUPERFAMILY SSF47979 64 137 3.79E-18 T 23-10-2018 IPR036421 Iron dependent repressor, metal binding and dimerisation domain superfamily GO:0046914|GO:0046983 A0127_03230 e28322e8b5df6eb22c65ad3e8ccd65e5 147 SMART SM00529 25 124 4.7E-42 T 23-10-2018 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 A0127_03230 e28322e8b5df6eb22c65ad3e8ccd65e5 147 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 64 129 7.0E-21 T 23-10-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 A0127_03020 357006a0eb71701492d993035e441fe9 347 Pfam PF05763 Protein of unknown function (DUF835) 226 346 1.2E-34 T 23-10-2018 IPR008553 Domain of unknown function DUF835 A0127_10025 ccabc8c0240f73dd48d3e196c9292529 290 Hamap MF_00769 2-phosphoglycerate kinase [pgk2]. 5 289 44.388 T 23-10-2018 IPR020872 2-phosphoglycerate kinase GO:0016774 A0127_10025 ccabc8c0240f73dd48d3e196c9292529 290 Pfam PF03477 ATP cone domain 13 87 1.0E-9 T 23-10-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 A0127_10025 ccabc8c0240f73dd48d3e196c9292529 290 Gene3D G3DSA:3.40.50.300 82 289 1.1E-6 T 23-10-2018 A0127_10025 ccabc8c0240f73dd48d3e196c9292529 290 SUPERFAMILY SSF52540 93 281 6.62E-10 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_04910 248b3c0ee308546a98df5b93282e278a 309 SUPERFAMILY SSF48179 174 296 1.56E-27 T 23-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 A0127_04910 248b3c0ee308546a98df5b93282e278a 309 Pfam PF02558 Ketopantoate reductase PanE/ApbA 3 146 8.6E-38 T 23-10-2018 IPR013332 Ketopantoate reductase, N-terminal domain A0127_04910 248b3c0ee308546a98df5b93282e278a 309 Gene3D G3DSA:3.40.50.720 1 171 3.4E-69 T 23-10-2018 A0127_04910 248b3c0ee308546a98df5b93282e278a 309 SUPERFAMILY SSF51735 1 150 3.94E-22 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A0127_04910 248b3c0ee308546a98df5b93282e278a 309 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 174 295 1.8E-31 T 23-10-2018 IPR013752 Ketopantoate reductase, C-terminal domain A0127_04910 248b3c0ee308546a98df5b93282e278a 309 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 2 296 2.0E-83 T 23-10-2018 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0008677|GO:0015940 KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 A0127_04910 248b3c0ee308546a98df5b93282e278a 309 Gene3D G3DSA:1.10.1040.10 172 296 1.1E-42 T 23-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 A0127_09980 c2f95a8593eb6e44b80526531bbcaa36 275 Pfam PF01008 Initiation factor 2 subunit family 18 271 3.6E-54 T 23-10-2018 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 A0127_09980 c2f95a8593eb6e44b80526531bbcaa36 275 Gene3D G3DSA:1.20.120.420 1 95 4.7E-33 T 23-10-2018 IPR027363 Methylthioribose-1-phosphate isomerase, N-terminal KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 A0127_09980 c2f95a8593eb6e44b80526531bbcaa36 275 Gene3D G3DSA:3.40.50.10470 96 275 5.1E-64 T 23-10-2018 A0127_09980 c2f95a8593eb6e44b80526531bbcaa36 275 SUPERFAMILY SSF100950 5 272 1.88E-71 T 23-10-2018 IPR037171 NagB/RpiA transferase-like A0127_05725 fd8fb8d7afb9e9bb35584ec96a1693b8 1323 TIGRFAM TIGR00354 polC: DNA polymerase II, large subunit DP2 9 1200 0.0 T 23-10-2018 IPR004475 DNA polymerase II large subunit DP2 GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A0127_05725 fd8fb8d7afb9e9bb35584ec96a1693b8 1323 Pfam PF03833 DNA polymerase II large subunit DP2 13 962 0.0 T 23-10-2018 IPR016033 DNA polymerase II large subunit DP2, N-terminal KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A0127_05725 fd8fb8d7afb9e9bb35584ec96a1693b8 1323 PIRSF PIRSF016275 1 1213 0.0 T 23-10-2018 IPR004475 DNA polymerase II large subunit DP2 GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A0127_05725 fd8fb8d7afb9e9bb35584ec96a1693b8 1323 Hamap MF_00324 DNA polymerase II large subunit [polC]. 1 1227 521.707 T 23-10-2018 IPR004475 DNA polymerase II large subunit DP2 GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 A0127_03575 2ce6c922f8efd867f0daf202bcb3f274 190 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 6 64 2.2E-18 T 23-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 A0127_03575 2ce6c922f8efd867f0daf202bcb3f274 190 Pfam PF01467 Cytidylyltransferase-like 8 139 1.1E-18 T 23-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 A0127_03575 2ce6c922f8efd867f0daf202bcb3f274 190 Hamap MF_00243 Nicotinamide-nucleotide adenylyltransferase. 1 190 92.124 T 23-10-2018 IPR006418 Nicotinamide-nucleotide adenylyltransferase, archaeal type GO:0000309|GO:0005737|GO:0009435 KEGG: 00760+2.7.7.1 A0127_03575 2ce6c922f8efd867f0daf202bcb3f274 190 TIGRFAM TIGR01527 arch_NMN_Atrans: nicotinamide-nucleotide adenylyltransferase 6 171 1.5E-69 T 23-10-2018 IPR006418 Nicotinamide-nucleotide adenylyltransferase, archaeal type GO:0000309|GO:0005737|GO:0009435 KEGG: 00760+2.7.7.1 A0127_03575 2ce6c922f8efd867f0daf202bcb3f274 190 Gene3D G3DSA:3.40.50.620 4 180 1.0E-55 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A0127_03575 2ce6c922f8efd867f0daf202bcb3f274 190 SUPERFAMILY SSF52374 5 169 8.89E-38 T 23-10-2018 A0127_09520 00596f379ed211d193b40cdde617cf35 139 PIRSF PIRSF004761 1 137 1.1E-36 T 23-10-2018 IPR000688 Hydrogenase maturation factor HypA/HybF GO:0016151|GO:0051604 A0127_09520 00596f379ed211d193b40cdde617cf35 139 Pfam PF01155 Hydrogenase/urease nickel incorporation, metallochaperone, hypA 1 132 1.3E-29 T 23-10-2018 IPR000688 Hydrogenase maturation factor HypA/HybF GO:0016151|GO:0051604 A0127_09520 00596f379ed211d193b40cdde617cf35 139 Hamap MF_00213 Hydrogenase maturation factor HypA [hypA]. 1 134 22.401 T 23-10-2018 IPR000688 Hydrogenase maturation factor HypA/HybF GO:0016151|GO:0051604 A0127_09520 00596f379ed211d193b40cdde617cf35 139 Gene3D G3DSA:3.30.2320.50 1 84 6.3E-29 T 23-10-2018 A0127_06175 f246d5beac4e6f95fe2e186f245cc223 290 SUPERFAMILY SSF103481 39 140 3.92E-11 T 23-10-2018 A0127_06175 f246d5beac4e6f95fe2e186f245cc223 290 Pfam PF00892 EamA-like transporter family 147 273 1.3E-26 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A0127_06175 f246d5beac4e6f95fe2e186f245cc223 290 Pfam PF00892 EamA-like transporter family 3 137 7.9E-25 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A0127_06175 f246d5beac4e6f95fe2e186f245cc223 290 SUPERFAMILY SSF103481 181 278 2.48E-17 T 23-10-2018 A0127_07275 7e251499648dfcf882db56baf13320ba 181 SUPERFAMILY SSF46785 59 171 1.45E-5 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A0127_07275 7e251499648dfcf882db56baf13320ba 181 TIGRFAM TIGR03879 near_KaiC_dom: probable regulatory domain 29 101 2.5E-26 T 23-10-2018 IPR022285 Conserved hypothetical protein CHP03879, regulatory domain, putative A0127_07275 7e251499648dfcf882db56baf13320ba 181 Gene3D G3DSA:1.10.10.60 55 83 2.7E-6 T 23-10-2018 A0127_01075 0717489454f8eb6d359247dae2c07b60 263 SMART SM00382 28 222 1.4E-14 T 23-10-2018 IPR003593 AAA+ ATPase domain A0127_01075 0717489454f8eb6d359247dae2c07b60 263 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A0127_01075 0717489454f8eb6d359247dae2c07b60 263 Pfam PF00005 ABC transporter 19 165 4.7E-29 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A0127_01075 0717489454f8eb6d359247dae2c07b60 263 SUPERFAMILY SSF52540 4 228 3.45E-56 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_01075 0717489454f8eb6d359247dae2c07b60 263 Gene3D G3DSA:3.40.50.300 1 243 2.0E-61 T 23-10-2018 A0127_00070 00658a82ffdd3ace32fc0d04818bead6 143 Pfam PF05763 Protein of unknown function (DUF835) 28 140 6.2E-21 T 23-10-2018 IPR008553 Domain of unknown function DUF835 A0127_04600 5ba1b424dd2249c23885bd0cda854b43 209 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 116 122 - T 23-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 A0127_04600 5ba1b424dd2249c23885bd0cda854b43 209 Gene3D G3DSA:3.40.50.150 1 207 1.1E-65 T 23-10-2018 A0127_04600 5ba1b424dd2249c23885bd0cda854b43 209 SUPERFAMILY SSF53335 3 202 2.29E-35 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A0127_04600 5ba1b424dd2249c23885bd0cda854b43 209 Pfam PF05175 Methyltransferase small domain 40 128 2.0E-15 T 23-10-2018 IPR007848 Methyltransferase small domain GO:0008168 A0127_08475 6d3e963c6de452ce46566a58a897125c 229 Gene3D G3DSA:3.75.10.10 1 228 1.9E-78 T 23-10-2018 A0127_08475 6d3e963c6de452ce46566a58a897125c 229 Pfam PF01912 eIF-6 family 5 206 2.6E-69 T 23-10-2018 IPR002769 Translation initiation factor IF6 GO:0042256|GO:0043022 A0127_08475 6d3e963c6de452ce46566a58a897125c 229 SMART SM00654 4 207 8.2E-104 T 23-10-2018 IPR002769 Translation initiation factor IF6 GO:0042256|GO:0043022 A0127_08475 6d3e963c6de452ce46566a58a897125c 229 SUPERFAMILY SSF55909 3 227 6.96E-75 T 23-10-2018 A0127_08475 6d3e963c6de452ce46566a58a897125c 229 PIRSF PIRSF006413 2 229 2.0E-78 T 23-10-2018 IPR002769 Translation initiation factor IF6 GO:0042256|GO:0043022 A0127_08475 6d3e963c6de452ce46566a58a897125c 229 TIGRFAM TIGR00323 eIF-6: putative translation initiation factor eIF-6 5 227 4.7E-63 T 23-10-2018 IPR002769 Translation initiation factor IF6 GO:0042256|GO:0043022 A0127_08475 6d3e963c6de452ce46566a58a897125c 229 Hamap MF_00032 Translation initiation factor 6 [eif6]. 1 229 99.297 T 23-10-2018 IPR002769 Translation initiation factor IF6 GO:0042256|GO:0043022 A0127_05975 d358443687cfd1a01c0ee3271684f7f3 278 Gene3D G3DSA:3.40.1190.20 1 276 7.7E-63 T 23-10-2018 IPR029056 Ribokinase-like A0127_05975 d358443687cfd1a01c0ee3271684f7f3 278 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 231 244 - T 23-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 A0127_05975 d358443687cfd1a01c0ee3271684f7f3 278 PRINTS PR00990 Ribokinase signature 161 176 9.5E-8 T 23-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A0127_05975 d358443687cfd1a01c0ee3271684f7f3 278 PRINTS PR00990 Ribokinase signature 200 211 9.5E-8 T 23-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A0127_05975 d358443687cfd1a01c0ee3271684f7f3 278 PRINTS PR00990 Ribokinase signature 22 41 9.5E-8 T 23-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 A0127_05975 d358443687cfd1a01c0ee3271684f7f3 278 SUPERFAMILY SSF53613 1 274 2.65E-58 T 23-10-2018 IPR029056 Ribokinase-like A0127_05975 d358443687cfd1a01c0ee3271684f7f3 278 Pfam PF00294 pfkB family carbohydrate kinase 2 271 1.9E-39 T 23-10-2018 IPR011611 Carbohydrate kinase PfkB A0127_04525 2534c276b130b88c1da938e1777e4e2c 263 Gene3D G3DSA:3.40.50.150 4 188 5.8E-19 T 23-10-2018 A0127_04525 2534c276b130b88c1da938e1777e4e2c 263 SUPERFAMILY SSF53335 22 209 3.62E-23 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A0127_04525 2534c276b130b88c1da938e1777e4e2c 263 Pfam PF13649 Methyltransferase domain 45 144 2.6E-10 T 23-10-2018 A0127_00175 33ba22cf32f11be95f2d845c9de4e806 281 Gene3D G3DSA:3.20.20.70 2 279 4.4E-82 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A0127_00175 33ba22cf32f11be95f2d845c9de4e806 281 SUPERFAMILY SSF51569 8 266 8.06E-69 T 23-10-2018 A0127_00175 33ba22cf32f11be95f2d845c9de4e806 281 Pfam PF01791 DeoC/LacD family aldolase 24 251 5.2E-34 T 23-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 A0127_00175 33ba22cf32f11be95f2d845c9de4e806 281 PIRSF PIRSF038992 4 281 9.1E-92 T 23-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 A0127_00175 33ba22cf32f11be95f2d845c9de4e806 281 SMART SM01133 23 251 1.8E-40 T 23-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 A0127_09205 168f83dde8675020fa4e023159fa9de1 140 SUPERFAMILY SSF54862 22 99 5.91E-11 T 23-10-2018 A0127_09205 168f83dde8675020fa4e023159fa9de1 140 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 72 83 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A0127_09205 168f83dde8675020fa4e023159fa9de1 140 Gene3D G3DSA:3.30.70.20 23 132 1.7E-7 T 23-10-2018 A0127_09205 168f83dde8675020fa4e023159fa9de1 140 Pfam PF00037 4Fe-4S binding domain 68 88 2.3E-7 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A0127_01080 e186b958a72676ac7b1da1d146c6ee2f 117 Pfam PF01176 Translation initiation factor 1A / IF-1 27 90 2.4E-20 T 23-10-2018 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 A0127_01080 e186b958a72676ac7b1da1d146c6ee2f 117 ProDom PD005579 INITIATION FACTOR TRANSLATION 1A BIOSYNTHESIS EUKARYOTIC EIF-1A AIF-1A EIF-4C 1A 48 105 2.0E-26 T 23-10-2018 IPR001253 Translation initiation factor 1A (eIF-1A) GO:0003743|GO:0006413 A0127_01080 e186b958a72676ac7b1da1d146c6ee2f 117 ProSitePatterns PS01262 Eukaryotic initiation factor 1A signature. 36 58 - T 23-10-2018 IPR018104 Translation initiation factor 1A (eIF-1A), conserved site GO:0003743|GO:0006413 A0127_01080 e186b958a72676ac7b1da1d146c6ee2f 117 TIGRFAM TIGR00523 eIF-1A: translation initiation factor eIF-1A 13 105 4.7E-36 T 23-10-2018 IPR001253 Translation initiation factor 1A (eIF-1A) GO:0003743|GO:0006413 A0127_01080 e186b958a72676ac7b1da1d146c6ee2f 117 SMART SM00652 23 106 5.9E-42 T 23-10-2018 IPR001253 Translation initiation factor 1A (eIF-1A) GO:0003743|GO:0006413 A0127_01080 e186b958a72676ac7b1da1d146c6ee2f 117 Hamap MF_00216 Translation initiation factor 1A [eif1a]. 10 106 28.384 T 23-10-2018 IPR001253 Translation initiation factor 1A (eIF-1A) GO:0003743|GO:0006413 A0127_01080 e186b958a72676ac7b1da1d146c6ee2f 117 Gene3D G3DSA:2.40.50.140 3 117 1.4E-38 T 23-10-2018 A0127_01080 e186b958a72676ac7b1da1d146c6ee2f 117 SUPERFAMILY SSF50249 3 109 2.37E-32 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A0127_04735 6075d32347a4c8352150e9d74f02ad3e 652 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 271 577 6.7E-19 T 23-10-2018 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 A0127_04735 6075d32347a4c8352150e9d74f02ad3e 652 Gene3D G3DSA:1.10.569.10 280 477 2.4E-13 T 23-10-2018 IPR013984 Aldehyde ferredoxin oxidoreductase, domain 2 A0127_04735 6075d32347a4c8352150e9d74f02ad3e 652 SUPERFAMILY SSF48310 242 650 1.15E-68 T 23-10-2018 IPR036021 Aldehyde ferredoxin oxidoreductase-like, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 A0127_04735 6075d32347a4c8352150e9d74f02ad3e 652 SUPERFAMILY SSF56228 3 228 9.55E-45 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily A0127_04735 6075d32347a4c8352150e9d74f02ad3e 652 SMART SM00790 1 226 2.1E-74 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 A0127_04735 6075d32347a4c8352150e9d74f02ad3e 652 Gene3D G3DSA:3.60.9.10 2 228 1.0E-23 T 23-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily A0127_04735 6075d32347a4c8352150e9d74f02ad3e 652 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 4 225 3.0E-41 T 23-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 A0127_07990 0a11bc321f80a7ec5c1d06cec6d868a0 229 Hamap MF_00170 Ribose-5-phosphate isomerase A [rpiA]. 3 227 36.452 T 23-10-2018 IPR020672 Ribose-5-phosphate isomerase, type A, subgroup GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 A0127_07990 0a11bc321f80a7ec5c1d06cec6d868a0 229 SUPERFAMILY SSF75445 133 209 7.19E-25 T 23-10-2018 A0127_07990 0a11bc321f80a7ec5c1d06cec6d868a0 229 Gene3D G3DSA:3.40.50.1360 7 223 1.3E-89 T 23-10-2018 A0127_07990 0a11bc321f80a7ec5c1d06cec6d868a0 229 TIGRFAM TIGR00021 rpiA: ribose 5-phosphate isomerase A 6 225 3.3E-83 T 23-10-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 A0127_07990 0a11bc321f80a7ec5c1d06cec6d868a0 229 Gene3D G3DSA:3.30.70.260 129 207 1.3E-89 T 23-10-2018 A0127_07990 0a11bc321f80a7ec5c1d06cec6d868a0 229 Pfam PF06026 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) 53 223 7.0E-66 T 23-10-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 A0127_07990 0a11bc321f80a7ec5c1d06cec6d868a0 229 SUPERFAMILY SSF100950 1 152 3.93E-47 T 23-10-2018 IPR037171 NagB/RpiA transferase-like A0127_01630 988905bdad4fc9608ca5928876e51941 330 SUPERFAMILY SSF53807 24 287 1.18E-44 T 23-10-2018 A0127_01630 988905bdad4fc9608ca5928876e51941 330 Gene3D G3DSA:3.40.50.1980 24 185 8.0E-27 T 23-10-2018 A0127_01630 988905bdad4fc9608ca5928876e51941 330 Pfam PF01297 Zinc-uptake complex component A periplasmic 28 285 1.4E-34 T 23-10-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 A0127_06445 237bcedfc4507e64e39b438b2ab1ee8e 250 Pfam PF01061 ABC-2 type transporter 9 219 3.8E-15 T 23-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 A0127_06445 237bcedfc4507e64e39b438b2ab1ee8e 250 PIRSF PIRSF006648 2 250 8.0E-21 T 23-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A0127_08140 c0d44273f036f7fe2b9d6581270e08f9 443 Gene3D G3DSA:1.20.1250.20 11 288 7.9E-17 T 23-10-2018 A0127_08140 c0d44273f036f7fe2b9d6581270e08f9 443 Gene3D G3DSA:1.20.1250.20 289 442 5.5E-14 T 23-10-2018 A0127_08140 c0d44273f036f7fe2b9d6581270e08f9 443 Pfam PF13347 MFS/sugar transport protein 50 405 3.5E-13 T 23-10-2018 A0127_08140 c0d44273f036f7fe2b9d6581270e08f9 443 SUPERFAMILY SSF103473 16 435 1.44E-39 T 23-10-2018 IPR036259 MFS transporter superfamily A0127_04690 8ebedce138a6eff9c6fc33702574150c 266 Gene3D G3DSA:2.40.50.140 9 141 5.5E-13 T 23-10-2018 A0127_04690 8ebedce138a6eff9c6fc33702574150c 266 Pfam PF01336 OB-fold nucleic acid binding domain 45 113 1.5E-7 T 23-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 A0127_04690 8ebedce138a6eff9c6fc33702574150c 266 SUPERFAMILY SSF50249 33 131 6.0E-11 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A0127_01415 3e993189c1f66bcee9272675cfafa7f1 314 SMART SM00382 31 216 2.2E-10 T 23-10-2018 IPR003593 AAA+ ATPase domain A0127_01415 3e993189c1f66bcee9272675cfafa7f1 314 SUPERFAMILY SSF52540 6 219 2.02E-59 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_01415 3e993189c1f66bcee9272675cfafa7f1 314 Gene3D G3DSA:3.40.50.300 1 225 1.1E-62 T 23-10-2018 A0127_01415 3e993189c1f66bcee9272675cfafa7f1 314 Pfam PF00005 ABC transporter 23 160 2.9E-28 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A0127_00240 57a9f8fa4f107c2179bf99321b161733 237 Pfam PF01881 CRISPR associated protein Cas6 81 233 1.2E-21 T 23-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 A0127_00240 57a9f8fa4f107c2179bf99321b161733 237 Gene3D G3DSA:3.30.70.1890 2 104 3.7E-6 T 23-10-2018 A0127_00240 57a9f8fa4f107c2179bf99321b161733 237 Gene3D G3DSA:3.30.70.1900 105 234 1.0E-10 T 23-10-2018 A0127_00240 57a9f8fa4f107c2179bf99321b161733 237 TIGRFAM TIGR01877 cas_cas6: CRISPR-associated endoribonuclease Cas6 37 233 1.4E-33 T 23-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 A0127_04805 690783458cbe4be24ec9f94afededa41 590 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 145 156 - T 23-10-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 A0127_04805 690783458cbe4be24ec9f94afededa41 590 Gene3D G3DSA:3.20.20.70 122 402 3.0E-33 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A0127_04805 690783458cbe4be24ec9f94afededa41 590 SUPERFAMILY SSF102114 128 396 7.06E-44 T 23-10-2018 A0127_04805 690783458cbe4be24ec9f94afededa41 590 Pfam PF04055 Radical SAM superfamily 143 302 4.2E-22 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A0127_04805 690783458cbe4be24ec9f94afededa41 590 Pfam PF13353 4Fe-4S single cluster domain 143 226 1.2E-6 T 23-10-2018 A0127_04185 183768b7bfed255737dc2b00fa32b01f 188 Pfam PF04017 Domain of unknown function (DUF366) 6 185 1.3E-69 T 23-10-2018 IPR007162 Protein of unknown function DUF366 A0127_04185 183768b7bfed255737dc2b00fa32b01f 188 Gene3D G3DSA:3.30.930.10 1 188 5.6E-73 T 23-10-2018 A0127_04185 183768b7bfed255737dc2b00fa32b01f 188 PIRSF PIRSF006503 1 188 1.8E-84 T 23-10-2018 IPR007162 Protein of unknown function DUF366 A0127_04185 183768b7bfed255737dc2b00fa32b01f 188 SUPERFAMILY SSF55681 3 186 3.65E-72 T 23-10-2018 A0127_04185 183768b7bfed255737dc2b00fa32b01f 188 ProDom PD022700 PH0223 5/5 GENOME PF0133 SEGMENT UNCHARACTERIZED MA4198 MJ0805 4 186 7.0E-94 T 23-10-2018 IPR007162 Protein of unknown function DUF366 A0127_06060 42a2d4ebc91d18d3007446c06b687eb9 514 Pfam PF01943 Polysaccharide biosynthesis protein 15 289 2.9E-29 T 23-10-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 A0127_06060 42a2d4ebc91d18d3007446c06b687eb9 514 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 345 477 6.5E-18 T 23-10-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain A0127_09110 72946ef26c9bbd1920ad04990246adc8 268 SUPERFAMILY SSF51658 10 238 1.7E-27 T 23-10-2018 IPR036237 Xylose isomerase-like superfamily A0127_09110 72946ef26c9bbd1920ad04990246adc8 268 Pfam PF01261 Xylose isomerase-like TIM barrel 29 228 4.2E-16 T 23-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain A0127_09110 72946ef26c9bbd1920ad04990246adc8 268 Gene3D G3DSA:3.20.20.150 5 256 1.6E-26 T 23-10-2018 A0127_06425 271403182e67632d0a73579da4419843 189 Pfam PF02834 LigT like Phosphoesterase 98 174 1.1E-13 T 23-10-2018 IPR014051 Phosphoesterase, HXTX A0127_06425 271403182e67632d0a73579da4419843 189 Pfam PF02834 LigT like Phosphoesterase 7 91 9.1E-21 T 23-10-2018 IPR014051 Phosphoesterase, HXTX A0127_06425 271403182e67632d0a73579da4419843 189 SUPERFAMILY SSF55144 1 182 2.09E-47 T 23-10-2018 IPR009097 Cyclic phosphodiesterase A0127_06425 271403182e67632d0a73579da4419843 189 Hamap MF_01940 RNA 2',3'-cyclic phosphodiesterase [thpR]. 1 182 27.296 T 23-10-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 A0127_06425 271403182e67632d0a73579da4419843 189 TIGRFAM TIGR02258 2_5_ligase: 2'-5' RNA ligase 1 182 9.7E-55 T 23-10-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 A0127_06425 271403182e67632d0a73579da4419843 189 Gene3D G3DSA:3.90.1140.10 1 184 1.1E-66 T 23-10-2018 A0127_05820 c8728690bfd26d8d8410bf313968efad 193 Gene3D G3DSA:1.10.20.10 90 191 1.3E-51 T 23-10-2018 IPR009072 Histone-fold GO:0046982 A0127_05820 c8728690bfd26d8d8410bf313968efad 193 Gene3D G3DSA:1.10.10.10 1 89 7.6E-32 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A0127_05820 c8728690bfd26d8d8410bf313968efad 193 SUPERFAMILY SSF46785 1 165 1.81E-35 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A0127_05820 c8728690bfd26d8d8410bf313968efad 193 SMART SM00418 11 105 1.1E-10 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A0127_05820 c8728690bfd26d8d8410bf313968efad 193 Pfam PF01022 Bacterial regulatory protein, arsR family 19 63 1.1E-15 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A0127_04760 cf5b487a50766e09efe970c710bfb45e 98 Pfam PF09876 Predicted metal-binding protein (DUF2103) 5 93 1.4E-23 T 23-10-2018 IPR018664 Protein of unknown function DUF2103, metal-binding A0127_10290 47539eb36b04e69149a3c88d2272637a 68 Gene3D G3DSA:3.30.70.100 3 68 4.6E-16 T 23-10-2018 A0127_10290 47539eb36b04e69149a3c88d2272637a 68 SUPERFAMILY SSF55008 1 67 3.67E-16 T 23-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 A0127_10290 47539eb36b04e69149a3c88d2272637a 68 Pfam PF00403 Heavy-metal-associated domain 5 64 3.5E-12 T 23-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 A0127_03035 d99c7429755aee1122fd4444c84455be 188 Hamap MF_01510 GMP synthase [glutamine-hydrolyzing] subunit A [guaAA]. 1 187 45.595 T 23-10-2018 IPR023686 GMP synthase (glutamine-hydrolyzing) subunit A GO:0003922 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 A0127_03035 d99c7429755aee1122fd4444c84455be 188 Gene3D G3DSA:3.40.50.880 1 187 1.1E-61 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A0127_03035 d99c7429755aee1122fd4444c84455be 188 Pfam PF00117 Glutamine amidotransferase class-I 4 181 3.5E-46 T 23-10-2018 IPR017926 Glutamine amidotransferase A0127_03035 d99c7429755aee1122fd4444c84455be 188 SUPERFAMILY SSF52317 1 186 1.07E-55 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A0127_03035 d99c7429755aee1122fd4444c84455be 188 PRINTS PR00097 Anthranilate synthase component II signature 161 174 1.1E-11 T 23-10-2018 A0127_03035 d99c7429755aee1122fd4444c84455be 188 PRINTS PR00097 Anthranilate synthase component II signature 46 55 1.1E-11 T 23-10-2018 A0127_03035 d99c7429755aee1122fd4444c84455be 188 PRINTS PR00097 Anthranilate synthase component II signature 2 16 1.1E-11 T 23-10-2018 A0127_03035 d99c7429755aee1122fd4444c84455be 188 PRINTS PR00097 Anthranilate synthase component II signature 73 84 1.1E-11 T 23-10-2018 A0127_03035 d99c7429755aee1122fd4444c84455be 188 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 2 186 4.4E-82 T 23-10-2018 IPR004739 GMP synthase, glutamine amidotransferase GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 A0127_03035 d99c7429755aee1122fd4444c84455be 188 PRINTS PR00096 Glutamine amidotransferase superfamily signature 161 174 4.2E-10 T 23-10-2018 A0127_03035 d99c7429755aee1122fd4444c84455be 188 PRINTS PR00096 Glutamine amidotransferase superfamily signature 73 84 4.2E-10 T 23-10-2018 A0127_03035 d99c7429755aee1122fd4444c84455be 188 PRINTS PR00096 Glutamine amidotransferase superfamily signature 46 55 4.2E-10 T 23-10-2018 A0127_03035 d99c7429755aee1122fd4444c84455be 188 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 43 57 9.8E-6 T 23-10-2018 A0127_03035 d99c7429755aee1122fd4444c84455be 188 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 73 89 9.8E-6 T 23-10-2018 A0127_00080 b49af14c22a8f2f1b630d9fa78d1857e 494 Gene3D G3DSA:1.20.1250.20 271 488 8.4E-17 T 23-10-2018 A0127_00080 b49af14c22a8f2f1b630d9fa78d1857e 494 Pfam PF07690 Major Facilitator Superfamily 27 417 8.3E-48 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A0127_00080 b49af14c22a8f2f1b630d9fa78d1857e 494 SUPERFAMILY SSF103473 16 485 5.23E-65 T 23-10-2018 IPR036259 MFS transporter superfamily A0127_00080 b49af14c22a8f2f1b630d9fa78d1857e 494 Gene3D G3DSA:1.20.1720.10 19 224 6.9E-47 T 23-10-2018 A0127_02430 a9f767a9318e3da1216a9d0077ece8f0 242 SMART SM00470 19 114 2.1E-11 T 23-10-2018 IPR003115 ParB/Sulfiredoxin A0127_02430 a9f767a9318e3da1216a9d0077ece8f0 242 SUPERFAMILY SSF110849 12 241 4.58E-61 T 23-10-2018 IPR036086 ParB/Sulfiredoxin superfamily A0127_02430 a9f767a9318e3da1216a9d0077ece8f0 242 Gene3D G3DSA:3.90.1530.10 17 238 1.4E-83 T 23-10-2018 A0127_02430 a9f767a9318e3da1216a9d0077ece8f0 242 Gene3D G3DSA:3.30.1760.10 98 227 1.4E-83 T 23-10-2018 IPR023098 ParB-like nuclease, C-terminal A0127_02430 a9f767a9318e3da1216a9d0077ece8f0 242 Pfam PF02195 ParB-like nuclease domain 22 92 1.2E-9 T 23-10-2018 IPR003115 ParB/Sulfiredoxin A0127_01110 e751ed81ab7a184b4cccf478813b5e19 139 Gene3D G3DSA:1.10.10.60 84 135 2.4E-7 T 23-10-2018 A0127_01110 e751ed81ab7a184b4cccf478813b5e19 139 SUPERFAMILY SSF46689 85 124 1.46E-7 T 23-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A0127_02255 6a97b600fe3c5a2854a0fbeaf96b7960 428 TIGRFAM TIGR00190 thiC: phosphomethylpyrimidine synthase 1 422 1.7E-187 T 23-10-2018 IPR002817 Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 A0127_02255 6a97b600fe3c5a2854a0fbeaf96b7960 428 Hamap MF_00089 Phosphomethylpyrimidine synthase [thiC]. 1 425 87.471 T 23-10-2018 IPR037509 Phosphomethylpyrimidine synthase GO:0009228|GO:0016830 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 A0127_02255 6a97b600fe3c5a2854a0fbeaf96b7960 428 Gene3D G3DSA:3.20.20.540 43 362 4.3E-139 T 23-10-2018 IPR038521 ThiC/Bza superfamily KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 A0127_02255 6a97b600fe3c5a2854a0fbeaf96b7960 428 Pfam PF01964 Radical SAM ThiC family 2 420 3.9E-182 T 23-10-2018 IPR002817 Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 A0127_00360 d0ba979259ed7ea307d738bffd9baf49 413 SUPERFAMILY SSF53448 1 299 1.13E-72 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A0127_00360 d0ba979259ed7ea307d738bffd9baf49 413 Gene3D G3DSA:2.160.10.10 237 371 4.0E-18 T 23-10-2018 A0127_00360 d0ba979259ed7ea307d738bffd9baf49 413 Pfam PF00483 Nucleotidyl transferase 2 230 7.6E-46 T 23-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 A0127_00360 d0ba979259ed7ea307d738bffd9baf49 413 Gene3D G3DSA:3.90.550.10 1 236 6.8E-73 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A0127_00360 d0ba979259ed7ea307d738bffd9baf49 413 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 312 342 3.1E-5 T 23-10-2018 IPR001451 Hexapeptide repeat A0127_00360 d0ba979259ed7ea307d738bffd9baf49 413 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 261 287 2.1E-4 T 23-10-2018 IPR001451 Hexapeptide repeat A0127_01840 adb30137f4864bb66c2ecf71a0a2407b 670 SUPERFAMILY SSF56300 130 422 1.06E-24 T 23-10-2018 A0127_01840 adb30137f4864bb66c2ecf71a0a2407b 670 TIGRFAM TIGR04288 CGP_CTERM: CGP-CTERM domain 650 669 4.7E-8 T 23-10-2018 IPR027552 CGP-CTERM domain A0127_01840 adb30137f4864bb66c2ecf71a0a2407b 670 Gene3D G3DSA:3.60.21.10 182 453 2.3E-14 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like A0127_06440 9eb73edb474564e816bd104411a8f4d0 280 SUPERFAMILY SSF52540 3 215 7.45E-57 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_06440 9eb73edb474564e816bd104411a8f4d0 280 Pfam PF00005 ABC transporter 18 162 9.7E-32 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A0127_06440 9eb73edb474564e816bd104411a8f4d0 280 SMART SM00382 27 211 2.3E-12 T 23-10-2018 IPR003593 AAA+ ATPase domain A0127_06440 9eb73edb474564e816bd104411a8f4d0 280 Gene3D G3DSA:3.40.50.300 1 236 3.7E-57 T 23-10-2018 A0127_09685 e40e1a07e791eb1873e366fe73e261f5 453 Hamap MF_00809 ADP-dependent glucokinase [glkA]. 1 453 59.142 T 23-10-2018 IPR031299 ADP-dependent glucokinase, archaeal KEGG: 00010+2.7.1.147|MetaCyc: PWY-6855 A0127_09685 e40e1a07e791eb1873e366fe73e261f5 453 Gene3D G3DSA:3.40.1190.20 24 447 4.9E-150 T 23-10-2018 IPR029056 Ribokinase-like A0127_09685 e40e1a07e791eb1873e366fe73e261f5 453 SUPERFAMILY SSF53613 3 451 1.85E-152 T 23-10-2018 IPR029056 Ribokinase-like A0127_09685 e40e1a07e791eb1873e366fe73e261f5 453 Pfam PF04587 ADP-specific Phosphofructokinase/Glucokinase conserved region 23 447 9.2E-96 T 23-10-2018 IPR007666 ADP-specific phosphofructokinase/glucokinase GO:0005975|GO:0016773 Reactome: R-HSA-70171 A0127_09685 e40e1a07e791eb1873e366fe73e261f5 453 PIRSF PIRSF015883 7 453 1.7E-158 T 23-10-2018 IPR015990 ADP-specific phosphofructokinase/glucokinase, archaeal GO:0000287|GO:0006096|GO:0016773 A0127_09685 e40e1a07e791eb1873e366fe73e261f5 453 Gene3D G3DSA:3.30.1110.20 31 203 4.9E-150 T 23-10-2018 A0127_06040 5ffbaacf3c07ef790ed67fcf91960f79 66 TIGRFAM TIGR04140 chp_AF_0576: TIGR04140 family protein 1 66 4.7E-25 T 23-10-2018 IPR026486 Uncharacterised protein AF_0576 A0127_09170 8087759e0526d7854685980d0884ff9d 312 SMART SM00382 30 230 1.6E-9 T 23-10-2018 IPR003593 AAA+ ATPase domain A0127_09170 8087759e0526d7854685980d0884ff9d 312 Gene3D G3DSA:3.40.50.300 2 234 4.2E-58 T 23-10-2018 A0127_09170 8087759e0526d7854685980d0884ff9d 312 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A0127_09170 8087759e0526d7854685980d0884ff9d 312 Pfam PF00005 ABC transporter 23 165 2.9E-28 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A0127_09170 8087759e0526d7854685980d0884ff9d 312 SUPERFAMILY SSF52540 4 224 1.0E-55 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_07515 ba0ffde55eed26a7f7b6c37a0d7e9211 88 Gene3D G3DSA:2.30.30.210 1 88 1.5E-31 T 23-10-2018 IPR036980 Ribonuclease P/MRP, subunit p29 superfamily GO:0003723|GO:0004540|GO:0008033|GO:0030677 Reactome: R-HSA-6784531 A0127_07515 ba0ffde55eed26a7f7b6c37a0d7e9211 88 Pfam PF01868 Domain of unknown function UPF0086 5 84 3.5E-19 T 23-10-2018 IPR002730 Ribonuclease P/MRP, subunit p29 GO:0003723|GO:0004540|GO:0006396|GO:0030677 Reactome: R-HSA-6784531 A0127_07515 ba0ffde55eed26a7f7b6c37a0d7e9211 88 SUPERFAMILY SSF101744 2 87 1.6E-24 T 23-10-2018 IPR023534 Rof/RNase P-like Reactome: R-HSA-6784531 A0127_07515 ba0ffde55eed26a7f7b6c37a0d7e9211 88 Hamap MF_00754 Ribonuclease P protein component 1 [rnp1]. 8 83 19.376 T 23-10-2018 IPR023538 Ribonuclease P protein component 1 GO:0001682|GO:0004526 A0127_07515 ba0ffde55eed26a7f7b6c37a0d7e9211 88 SMART SM00538 1 88 4.1E-30 T 23-10-2018 IPR002730 Ribonuclease P/MRP, subunit p29 GO:0003723|GO:0004540|GO:0006396|GO:0030677 Reactome: R-HSA-6784531 A0127_01565 827be0e3194606e9b25c1f821b3efc4b 290 Gene3D G3DSA:3.30.2010.10 62 151 5.3E-33 T 23-10-2018 A0127_01565 827be0e3194606e9b25c1f821b3efc4b 290 Hamap MF_00188 Protease HtpX [htpX]. 6 282 30.112 T 23-10-2018 IPR022919 Peptidase M48, protease HtpX, putative GO:0004222 A0127_01565 827be0e3194606e9b25c1f821b3efc4b 290 Pfam PF01435 Peptidase family M48 68 282 2.2E-37 T 23-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 A0127_04790 0be751d338cdfa6e1678b3f098899527 484 PIRSF PIRSF016666 1 484 2.3E-259 T 23-10-2018 IPR016675 Uncharacterised conserved protein UCP016666 A0127_04790 0be751d338cdfa6e1678b3f098899527 484 SUPERFAMILY SSF75011 75 228 1.44E-10 T 23-10-2018 A0127_04790 0be751d338cdfa6e1678b3f098899527 484 Pfam PF09910 Uncharacterized protein conserved in archaea (DUF2139) 31 362 1.1E-152 T 23-10-2018 IPR016675 Uncharacterised conserved protein UCP016666 A0127_08940 d361edb0f772f98874e131855a7fd7f8 440 Gene3D G3DSA:2.40.50.360 119 243 4.2E-114 T 23-10-2018 A0127_08940 d361edb0f772f98874e131855a7fd7f8 440 SUPERFAMILY SSF50249 126 207 2.4E-19 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A0127_08940 d361edb0f772f98874e131855a7fd7f8 440 Gene3D G3DSA:1.10.8.60 354 438 1.5E-26 T 23-10-2018 A0127_08940 d361edb0f772f98874e131855a7fd7f8 440 SMART SM00382 62 353 3.6E-13 T 23-10-2018 IPR003593 AAA+ ATPase domain A0127_08940 d361edb0f772f98874e131855a7fd7f8 440 Pfam PF06068 TIP49 C-terminus 14 403 4.1E-162 T 23-10-2018 IPR010339 TIP49, C-terminal GO:0003678|GO:0005524 Reactome: R-HSA-171319|Reactome: R-HSA-3214847 A0127_08940 d361edb0f772f98874e131855a7fd7f8 440 Gene3D G3DSA:3.40.50.300 18 349 4.2E-114 T 23-10-2018 A0127_08940 d361edb0f772f98874e131855a7fd7f8 440 SUPERFAMILY SSF52540 37 423 3.67E-40 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_03875 2f719e0e7756d679a6fb94816beb0b42 118 SUPERFAMILY SSF102462 3 118 8.89E-43 T 23-10-2018 IPR023476 Peptidyl-tRNA hydrolase II domain superfamily MetaCyc: PWY-6308 A0127_03875 2f719e0e7756d679a6fb94816beb0b42 118 Hamap MF_00628 Peptidyl-tRNA hydrolase [pth]. 4 118 29.851 T 23-10-2018 IPR034759 Peptidyl-tRNA hydrolase, archaea GO:0004045 MetaCyc: PWY-6308 A0127_03875 2f719e0e7756d679a6fb94816beb0b42 118 Gene3D G3DSA:3.40.1490.10 1 118 1.5E-48 T 23-10-2018 IPR023476 Peptidyl-tRNA hydrolase II domain superfamily MetaCyc: PWY-6308 A0127_03875 2f719e0e7756d679a6fb94816beb0b42 118 Pfam PF01981 Peptidyl-tRNA hydrolase PTH2 4 118 5.5E-44 T 23-10-2018 IPR002833 Peptidyl-tRNA hydrolase, PTH2 GO:0004045 MetaCyc: PWY-6308 A0127_03875 2f719e0e7756d679a6fb94816beb0b42 118 TIGRFAM TIGR00283 arch_pth2: peptidyl-tRNA hydrolase 5 118 1.9E-42 T 23-10-2018 IPR002833 Peptidyl-tRNA hydrolase, PTH2 GO:0004045 MetaCyc: PWY-6308 A0127_09535 8fb588abff65748cb5f57bc242bedac8 146 Pfam PF08859 DGC domain 26 130 1.4E-29 T 23-10-2018 IPR014958 DGC A0127_09535 8fb588abff65748cb5f57bc242bedac8 146 PIRSF PIRSF037181 10 145 1.8E-29 T 23-10-2018 IPR014958 DGC A0127_02200 2fd4ccca4c0dc185a8864a8daadcfda8 191 Gene3D G3DSA:2.130.10.120 18 108 3.1E-14 T 23-10-2018 A0127_02200 2fd4ccca4c0dc185a8864a8daadcfda8 191 Gene3D G3DSA:3.40.50.1820 109 135 3.1E-14 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold A0127_02200 2fd4ccca4c0dc185a8864a8daadcfda8 191 SUPERFAMILY SSF50993 22 108 5.49E-7 T 23-10-2018 A0127_04220 8a6eec414270f7c8d1e28e6189a9c460 121 SUPERFAMILY SSF88697 3 114 5.96E-31 T 23-10-2018 IPR015947 PUA-like superfamily A0127_04220 8a6eec414270f7c8d1e28e6189a9c460 121 Pfam PF04266 ASCH domain 11 102 1.8E-13 T 23-10-2018 IPR007374 ASCH domain A0127_04220 8a6eec414270f7c8d1e28e6189a9c460 121 Gene3D G3DSA:2.30.130.30 6 105 2.2E-34 T 23-10-2018 A0127_04220 8a6eec414270f7c8d1e28e6189a9c460 121 SMART SM01022 9 103 8.0E-10 T 23-10-2018 IPR007374 ASCH domain A0127_02335 4d54d91d993aac3676dcab3def0a936a 70 Pfam PF01022 Bacterial regulatory protein, arsR family 5 42 8.1E-5 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A0127_02335 4d54d91d993aac3676dcab3def0a936a 70 Gene3D G3DSA:1.10.10.10 1 70 4.2E-9 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A0127_02335 4d54d91d993aac3676dcab3def0a936a 70 SUPERFAMILY SSF46785 5 51 1.75E-9 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A0127_04875 0b27fc2d6611d080375c54c4a5d645e6 184 SUPERFAMILY SSF53639 4 182 8.24E-56 T 23-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily A0127_04875 0b27fc2d6611d080375c54c4a5d645e6 184 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 7 179 3.2E-48 T 23-10-2018 IPR001303 Class II aldolase/adducin N-terminal A0127_04875 0b27fc2d6611d080375c54c4a5d645e6 184 Gene3D G3DSA:3.40.225.10 2 184 4.6E-61 T 23-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily A0127_04875 0b27fc2d6611d080375c54c4a5d645e6 184 SMART SM01007 6 180 2.8E-59 T 23-10-2018 IPR001303 Class II aldolase/adducin N-terminal A0127_05425 736ac07148ee9353c22b66283e616097 171 SUPERFAMILY SSF46785 5 99 7.35E-23 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A0127_05425 736ac07148ee9353c22b66283e616097 171 Pfam PF03551 Transcriptional regulator PadR-like family 18 92 1.4E-16 T 23-10-2018 IPR005149 Transcription regulator PadR, N-terminal A0127_05425 736ac07148ee9353c22b66283e616097 171 Gene3D G3DSA:1.10.10.10 5 114 1.7E-20 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A0127_09225 c0b0468cb333790cbe8138b5220659f2 455 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 443 42.014 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A0127_09225 c0b0468cb333790cbe8138b5220659f2 455 PIRSF PIRSF001529 1 447 4.8E-155 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A0127_09225 c0b0468cb333790cbe8138b5220659f2 455 SUPERFAMILY SSF55681 158 445 5.39E-89 T 23-10-2018 A0127_09225 c0b0468cb333790cbe8138b5220659f2 455 PRINTS PR00981 Seryl-tRNA synthetase signature 372 388 2.5E-33 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A0127_09225 c0b0468cb333790cbe8138b5220659f2 455 PRINTS PR00981 Seryl-tRNA synthetase signature 285 297 2.5E-33 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A0127_09225 c0b0468cb333790cbe8138b5220659f2 455 PRINTS PR00981 Seryl-tRNA synthetase signature 354 370 2.5E-33 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A0127_09225 c0b0468cb333790cbe8138b5220659f2 455 PRINTS PR00981 Seryl-tRNA synthetase signature 297 310 2.5E-33 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A0127_09225 c0b0468cb333790cbe8138b5220659f2 455 PRINTS PR00981 Seryl-tRNA synthetase signature 337 350 2.5E-33 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A0127_09225 c0b0468cb333790cbe8138b5220659f2 455 TIGRFAM TIGR00414 serS: serine--tRNA ligase 1 438 6.9E-162 T 23-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 A0127_09225 c0b0468cb333790cbe8138b5220659f2 455 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 109 1.2E-27 T 23-10-2018 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: R-HSA-2408557|Reactome: R-HSA-379716 A0127_09225 c0b0468cb333790cbe8138b5220659f2 455 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 243 421 1.0E-38 T 23-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 A0127_09225 c0b0468cb333790cbe8138b5220659f2 455 Gene3D G3DSA:1.10.287.40 1 107 1.6E-34 T 23-10-2018 A0127_09225 c0b0468cb333790cbe8138b5220659f2 455 SUPERFAMILY SSF46589 1 115 6.28E-28 T 23-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 A0127_09225 c0b0468cb333790cbe8138b5220659f2 455 Gene3D G3DSA:3.30.930.10 108 455 2.2E-136 T 23-10-2018 A0127_06560 6dbbf780642e7eb66eea739d27e92d10 200 SUPERFAMILY SSF46785 7 150 2.4E-7 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A0127_09200 eea9ea1ffab239fb65ae1a8feaf99fca 408 SUPERFAMILY SSF53748 2 399 2.94E-116 T 23-10-2018 IPR036043 Phosphoglycerate kinase superfamily GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A0127_09200 eea9ea1ffab239fb65ae1a8feaf99fca 408 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 4 400 34.77 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A0127_09200 eea9ea1ffab239fb65ae1a8feaf99fca 408 Gene3D G3DSA:3.40.50.1260 189 390 1.1E-136 T 23-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A0127_09200 eea9ea1ffab239fb65ae1a8feaf99fca 408 Gene3D G3DSA:3.40.50.1260 10 397 1.1E-136 T 23-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A0127_09200 eea9ea1ffab239fb65ae1a8feaf99fca 408 ProSitePatterns PS00111 Phosphoglycerate kinase signature. 13 23 - T 23-10-2018 IPR015911 Phosphoglycerate kinase, conserved site GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A0127_09200 eea9ea1ffab239fb65ae1a8feaf99fca 408 Pfam PF00162 Phosphoglycerate kinase 5 389 6.3E-106 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A0127_09200 eea9ea1ffab239fb65ae1a8feaf99fca 408 PIRSF PIRSF000724 1 407 2.4E-129 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A0127_09200 eea9ea1ffab239fb65ae1a8feaf99fca 408 PRINTS PR00477 Phosphoglycerate kinase family signature 29 51 1.7E-66 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A0127_09200 eea9ea1ffab239fb65ae1a8feaf99fca 408 PRINTS PR00477 Phosphoglycerate kinase family signature 170 192 1.7E-66 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A0127_09200 eea9ea1ffab239fb65ae1a8feaf99fca 408 PRINTS PR00477 Phosphoglycerate kinase family signature 105 120 1.7E-66 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A0127_09200 eea9ea1ffab239fb65ae1a8feaf99fca 408 PRINTS PR00477 Phosphoglycerate kinase family signature 140 162 1.7E-66 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A0127_09200 eea9ea1ffab239fb65ae1a8feaf99fca 408 PRINTS PR00477 Phosphoglycerate kinase family signature 376 393 1.7E-66 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A0127_09200 eea9ea1ffab239fb65ae1a8feaf99fca 408 PRINTS PR00477 Phosphoglycerate kinase family signature 8 24 1.7E-66 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A0127_09200 eea9ea1ffab239fb65ae1a8feaf99fca 408 PRINTS PR00477 Phosphoglycerate kinase family signature 321 346 1.7E-66 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A0127_09200 eea9ea1ffab239fb65ae1a8feaf99fca 408 PRINTS PR00477 Phosphoglycerate kinase family signature 193 212 1.7E-66 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A0127_09200 eea9ea1ffab239fb65ae1a8feaf99fca 408 PRINTS PR00477 Phosphoglycerate kinase family signature 354 365 1.7E-66 T 23-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 A0127_08765 b19dcce2f6be10a3ce30c90e5ae17baf 377 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 28 360 1.0E-117 T 23-10-2018 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 A0127_08765 b19dcce2f6be10a3ce30c90e5ae17baf 377 TIGRFAM TIGR00236 wecB: UDP-N-acetylglucosamine 2-epimerase 2 362 1.3E-129 T 23-10-2018 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 A0127_08765 b19dcce2f6be10a3ce30c90e5ae17baf 377 Gene3D G3DSA:3.40.50.2000 6 357 1.5E-132 T 23-10-2018 A0127_08765 b19dcce2f6be10a3ce30c90e5ae17baf 377 SUPERFAMILY SSF53756 2 365 7.46E-121 T 23-10-2018 A0127_08765 b19dcce2f6be10a3ce30c90e5ae17baf 377 Gene3D G3DSA:3.40.50.2000 183 347 1.5E-132 T 23-10-2018 A0127_08980 104e424d48787a45e778b4db56e75261 130 Pfam PF01201 Ribosomal protein S8e 2 125 1.5E-33 T 23-10-2018 IPR022309 Ribosomal protein S8e/ribosomal biogenesis NSA2 A0127_08980 104e424d48787a45e778b4db56e75261 130 TIGRFAM TIGR00307 eS8: ribosomal protein eS8 1 127 3.7E-48 T 23-10-2018 IPR001047 Ribosomal protein S8e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_08980 104e424d48787a45e778b4db56e75261 130 ProSitePatterns PS01193 Ribosomal protein S8e signature. 10 29 - T 23-10-2018 IPR018283 Ribosomal protein S8e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_08980 104e424d48787a45e778b4db56e75261 130 Gene3D G3DSA:2.40.10.310 61 130 1.8E-32 T 23-10-2018 A0127_08980 104e424d48787a45e778b4db56e75261 130 Hamap MF_00029 30S ribosomal protein S8e [rps8e]. 2 126 32.497 T 23-10-2018 IPR020919 Ribosomal protein S8e, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 A0127_09115 a9e0b3622b7f5ff31f7bba224b614045 333 SUPERFAMILY SSF52096 82 281 1.31E-36 T 23-10-2018 IPR029045 ClpP/crotonase-like domain superfamily A0127_09115 a9e0b3622b7f5ff31f7bba224b614045 333 Gene3D G3DSA:3.90.226.10 89 286 1.5E-53 T 23-10-2018 A0127_09115 a9e0b3622b7f5ff31f7bba224b614045 333 Pfam PF01343 Peptidase family S49 149 294 2.4E-42 T 23-10-2018 IPR002142 Peptidase S49 GO:0006508|GO:0008233 A0127_09115 a9e0b3622b7f5ff31f7bba224b614045 333 Gene3D G3DSA:3.40.1750.20 185 251 1.5E-53 T 23-10-2018 A0127_09115 a9e0b3622b7f5ff31f7bba224b614045 333 TIGRFAM TIGR00706 SppA_dom: signal peptide peptidase SppA, 36K type 87 292 2.4E-69 T 23-10-2018 IPR004635 Peptidase S49, SppA GO:0006508|GO:0008233 A0127_00265 440d224761f4700e711aecb1142bbe8b 76 SMART SM00651 7 72 1.2E-20 T 23-10-2018 IPR001163 LSM domain, eukaryotic/archaea-type A0127_00265 440d224761f4700e711aecb1142bbe8b 76 Pfam PF01423 LSM domain 8 72 1.8E-19 T 23-10-2018 IPR001163 LSM domain, eukaryotic/archaea-type A0127_00265 440d224761f4700e711aecb1142bbe8b 76 Gene3D G3DSA:2.30.30.100 1 74 4.6E-24 T 23-10-2018 A0127_00265 440d224761f4700e711aecb1142bbe8b 76 Hamap MF_00257 Putative snRNP Sm-like protein. 1 72 25.652 T 23-10-2018 IPR022901 snRNP Sm-like, putative, archaea A0127_00265 440d224761f4700e711aecb1142bbe8b 76 SUPERFAMILY SSF50182 5 74 6.04E-18 T 23-10-2018 IPR010920 LSM domain superfamily A0127_01435 12be743eed2ae75127d1a0ae8a819307 137 SUPERFAMILY SSF53146 4 117 2.22E-14 T 23-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily A0127_01435 12be743eed2ae75127d1a0ae8a819307 137 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 15 115 2.5E-14 T 23-10-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis A0127_01435 12be743eed2ae75127d1a0ae8a819307 137 Gene3D G3DSA:3.30.420.130 1 128 3.3E-14 T 23-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily A0127_08260 1065b7ea4bafd66813031d1fda0d9dfb 473 PIRSF PIRSF006603 3 473 1.2E-162 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A0127_08260 1065b7ea4bafd66813031d1fda0d9dfb 473 TIGRFAM TIGR00797 matE: MATE efflux family protein 28 423 3.9E-70 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A0127_08260 1065b7ea4bafd66813031d1fda0d9dfb 473 Pfam PF01554 MatE 28 188 1.4E-31 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A0127_08260 1065b7ea4bafd66813031d1fda0d9dfb 473 Pfam PF01554 MatE 253 415 1.5E-26 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A0127_08635 33846488e65f932191f53fb825cdb884 149 Pfam PF13412 Winged helix-turn-helix DNA-binding 6 51 3.2E-15 T 23-10-2018 A0127_08635 33846488e65f932191f53fb825cdb884 149 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 32 51 9.7E-12 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A0127_08635 33846488e65f932191f53fb825cdb884 149 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 5 21 9.7E-12 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A0127_08635 33846488e65f932191f53fb825cdb884 149 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 21 32 9.7E-12 T 23-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 A0127_08635 33846488e65f932191f53fb825cdb884 149 SMART SM00344 8 111 4.3E-21 T 23-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 A0127_08635 33846488e65f932191f53fb825cdb884 149 Gene3D G3DSA:3.30.70.920 57 149 1.4E-28 T 23-10-2018 A0127_08635 33846488e65f932191f53fb825cdb884 149 Gene3D G3DSA:1.10.10.10 1 56 1.4E-19 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A0127_08635 33846488e65f932191f53fb825cdb884 149 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 20 36 3.6E-5 T 23-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 A0127_08635 33846488e65f932191f53fb825cdb884 149 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 36 51 3.6E-5 T 23-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 A0127_08635 33846488e65f932191f53fb825cdb884 149 SUPERFAMILY SSF54909 67 147 2.68E-5 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel A0127_08635 33846488e65f932191f53fb825cdb884 149 SUPERFAMILY SSF46785 5 79 5.38E-14 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A0127_00570 1578bf56c645ed2b734c39ee97b7cff4 97 Gene3D G3DSA:2.20.28.10 1 97 8.1E-35 T 23-10-2018 A0127_00570 1578bf56c645ed2b734c39ee97b7cff4 97 SUPERFAMILY SSF46785 2 96 4.62E-35 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A0127_07100 85a66bd27507a6814625eba45306d2e3 142 Hamap MF_00232 Translation initiation factor 2 subunit beta [eif2b]. 8 142 33.43 T 23-10-2018 IPR004458 Translation initiation factor 2, beta subunit GO:0003743|GO:0006413 A0127_07100 85a66bd27507a6814625eba45306d2e3 142 Pfam PF01873 Domain found in IF2B/IF5 23 135 3.2E-37 T 23-10-2018 IPR002735 Translation initiation factor IF2/IF5 GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 A0127_07100 85a66bd27507a6814625eba45306d2e3 142 Gene3D G3DSA:3.30.70.3150 40 130 5.6E-32 T 23-10-2018 A0127_07100 85a66bd27507a6814625eba45306d2e3 142 TIGRFAM TIGR00311 aIF-2beta: putative translation initiation factor aIF-2, beta subunit 9 141 7.9E-52 T 23-10-2018 IPR004458 Translation initiation factor 2, beta subunit GO:0003743|GO:0006413 A0127_07100 85a66bd27507a6814625eba45306d2e3 142 SMART SM00653 29 136 6.8E-59 T 23-10-2018 IPR002735 Translation initiation factor IF2/IF5 GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 A0127_07100 85a66bd27507a6814625eba45306d2e3 142 SUPERFAMILY SSF75689 106 141 7.85E-12 T 23-10-2018 IPR016190 Translation initiation factor IF2/IF5, zinc-binding GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 A0127_07100 85a66bd27507a6814625eba45306d2e3 142 SUPERFAMILY SSF100966 8 109 1.96E-28 T 23-10-2018 IPR016189 Translation initiation factor IF2/IF5, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 A0127_08110 56abaa5c5fb2ded8ba4b602b97f65186 436 SUPERFAMILY SSF161070 11 400 3.66E-12 T 23-10-2018 IPR037272 Sodium:neurotransmitter symporter superfamily GO:0005328 A0127_06790 f8d43333696af07c7aa3e107bc073059 351 Pfam PF01861 Protein of unknown function DUF43 106 350 6.5E-121 T 23-10-2018 IPR002723 N(4)-bis(aminopropyl)spermidine synthase, C-terminal A0127_06790 f8d43333696af07c7aa3e107bc073059 351 Hamap MF_01947 N(4)-bis(aminopropyl)spermidine synthase [bpsA]. 15 351 50.514 T 23-10-2018 IPR014435 N(4)-bis(aminopropyl)spermidine synthase GO:0006596|GO:0016765 A0127_06790 f8d43333696af07c7aa3e107bc073059 351 Gene3D G3DSA:1.10.10.10 1 83 7.1E-32 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A0127_06790 f8d43333696af07c7aa3e107bc073059 351 Gene3D G3DSA:3.40.50.150 101 326 2.4E-85 T 23-10-2018 A0127_06790 f8d43333696af07c7aa3e107bc073059 351 SUPERFAMILY SSF53335 118 285 2.14E-8 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A0127_06790 f8d43333696af07c7aa3e107bc073059 351 PIRSF PIRSF005895 1 351 5.1E-158 T 23-10-2018 IPR014435 N(4)-bis(aminopropyl)spermidine synthase GO:0006596|GO:0016765 A0127_07380 8c01bd200d45b95d76603b7adcb3e478 185 Gene3D G3DSA:3.10.580.10 2 103 2.0E-12 T 23-10-2018 A0127_07380 8c01bd200d45b95d76603b7adcb3e478 185 SMART SM00116 133 181 1.8E-9 T 23-10-2018 IPR000644 CBS domain A0127_07380 8c01bd200d45b95d76603b7adcb3e478 185 SMART SM00116 55 102 1.8E-4 T 23-10-2018 IPR000644 CBS domain A0127_07380 8c01bd200d45b95d76603b7adcb3e478 185 Gene3D G3DSA:3.10.580.10 104 183 3.7E-16 T 23-10-2018 A0127_07380 8c01bd200d45b95d76603b7adcb3e478 185 Pfam PF00571 CBS domain 126 180 1.5E-14 T 23-10-2018 IPR000644 CBS domain A0127_07380 8c01bd200d45b95d76603b7adcb3e478 185 Pfam PF00571 CBS domain 51 100 1.9E-11 T 23-10-2018 IPR000644 CBS domain A0127_07380 8c01bd200d45b95d76603b7adcb3e478 185 SUPERFAMILY SSF54631 36 180 6.38E-30 T 23-10-2018 A0127_06055 93d5880e4e2aef04ff0e4ecb08df40df 386 SUPERFAMILY SSF50156 213 301 5.78E-24 T 23-10-2018 IPR036034 PDZ superfamily GO:0005515 A0127_06055 93d5880e4e2aef04ff0e4ecb08df40df 386 Gene3D G3DSA:2.30.42.10 213 300 6.1E-25 T 23-10-2018 A0127_06055 93d5880e4e2aef04ff0e4ecb08df40df 386 PRINTS PR01000 Sterol regulatory element binding protein site 2 protease (M50) signature 132 146 1.3E-20 T 23-10-2018 IPR001193 Membrane-bound transcription factor site-2 protease GO:0004222|GO:0006508|GO:0016020 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 A0127_06055 93d5880e4e2aef04ff0e4ecb08df40df 386 PRINTS PR01000 Sterol regulatory element binding protein site 2 protease (M50) signature 148 163 1.3E-20 T 23-10-2018 IPR001193 Membrane-bound transcription factor site-2 protease GO:0004222|GO:0006508|GO:0016020 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 A0127_06055 93d5880e4e2aef04ff0e4ecb08df40df 386 PRINTS PR01000 Sterol regulatory element binding protein site 2 protease (M50) signature 112 131 1.3E-20 T 23-10-2018 IPR001193 Membrane-bound transcription factor site-2 protease GO:0004222|GO:0006508|GO:0016020 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 A0127_06055 93d5880e4e2aef04ff0e4ecb08df40df 386 PRINTS PR01000 Sterol regulatory element binding protein site 2 protease (M50) signature 164 176 1.3E-20 T 23-10-2018 IPR001193 Membrane-bound transcription factor site-2 protease GO:0004222|GO:0006508|GO:0016020 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 A0127_06055 93d5880e4e2aef04ff0e4ecb08df40df 386 SMART SM00228 199 272 3.7E-12 T 23-10-2018 IPR001478 PDZ domain GO:0005515 A0127_06055 93d5880e4e2aef04ff0e4ecb08df40df 386 Pfam PF13180 PDZ domain 215 281 1.9E-13 T 23-10-2018 IPR001478 PDZ domain GO:0005515 A0127_06055 93d5880e4e2aef04ff0e4ecb08df40df 386 Pfam PF02163 Peptidase family M50 124 373 4.9E-22 T 23-10-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 A0127_07370 9afa86a59893641de8e326b42784e34c 375 Pfam PF00999 Sodium/hydrogen exchanger family 8 369 4.8E-67 T 23-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 A0127_07370 9afa86a59893641de8e326b42784e34c 375 Gene3D G3DSA:1.20.1530.20 1 374 2.6E-85 T 23-10-2018 IPR038770 Sodium/solute symporter superfamily A0127_06605 73e2cc95dcf74570a670073f61bd3d70 767 Pfam PF02516 Oligosaccharyl transferase STT3 subunit 31 509 5.1E-13 T 23-10-2018 IPR003674 Oligosaccharyl transferase, STT3 subunit GO:0004576|GO:0006486|GO:0016020 A0127_06605 73e2cc95dcf74570a670073f61bd3d70 767 Gene3D G3DSA:3.40.50.12610 465 581 2.5E-15 T 23-10-2018 A0127_09595 044addaa64b280a21a677347d99f1b4c 341 Pfam PF01758 Sodium Bile acid symporter family 46 235 2.7E-46 T 23-10-2018 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 A0127_09595 044addaa64b280a21a677347d99f1b4c 341 Gene3D G3DSA:1.20.1530.20 7 326 9.9E-43 T 23-10-2018 IPR038770 Sodium/solute symporter superfamily A0127_04695 e838b39dc716bc75ed0aaa3a5421854f 125 SUPERFAMILY SSF50249 23 88 5.31E-6 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A0127_04945 fb2fbca4123d0fd93f572635d7ec326d 121 Gene3D G3DSA:3.40.50.1010 2 120 1.5E-14 T 23-10-2018 A0127_04945 fb2fbca4123d0fd93f572635d7ec326d 121 Pfam PF01850 PIN domain 3 117 4.9E-18 T 23-10-2018 IPR002716 PIN domain A0127_04945 fb2fbca4123d0fd93f572635d7ec326d 121 SUPERFAMILY SSF88723 2 120 7.57E-21 T 23-10-2018 IPR029060 PIN-like domain superfamily A0127_07210 e0f8f4e3a5feb8f4637e36896399d2a9 214 TIGRFAM TIGR00309 V_ATPase_subD: V-type ATPase, D subunit 6 209 3.5E-70 T 23-10-2018 IPR002699 ATPase, V1 complex, subunit D GO:0042626 Reactome: R-HSA-1222556|Reactome: R-HSA-6798695|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A0127_07210 e0f8f4e3a5feb8f4637e36896399d2a9 214 Hamap MF_00271 V-type ATP synthase subunit D [atpD]. 4 211 25.627 T 23-10-2018 IPR002699 ATPase, V1 complex, subunit D GO:0042626 Reactome: R-HSA-1222556|Reactome: R-HSA-6798695|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A0127_07210 e0f8f4e3a5feb8f4637e36896399d2a9 214 Pfam PF01813 ATP synthase subunit D 13 206 5.7E-62 T 23-10-2018 IPR002699 ATPase, V1 complex, subunit D GO:0042626 Reactome: R-HSA-1222556|Reactome: R-HSA-6798695|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A0127_07235 c3e2acb5454183f8f9b168dbc0381ff8 203 SUPERFAMILY SSF160527 81 203 8.89E-25 T 23-10-2018 A0127_07235 c3e2acb5454183f8f9b168dbc0381ff8 203 Pfam PF01991 ATP synthase (E/31 kDa) subunit 10 202 4.9E-39 T 23-10-2018 IPR002842 V-type ATPase subunit E GO:0015991|GO:0033178|GO:0046961 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A0127_07235 c3e2acb5454183f8f9b168dbc0381ff8 203 Hamap MF_00311 V-type proton ATPase subunit E [atpE]. 2 203 15.155 T 23-10-2018 IPR002842 V-type ATPase subunit E GO:0015991|GO:0033178|GO:0046961 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A0127_07235 c3e2acb5454183f8f9b168dbc0381ff8 203 Gene3D G3DSA:1.20.5.620 18 98 5.0E-26 T 23-10-2018 A0127_07235 c3e2acb5454183f8f9b168dbc0381ff8 203 Gene3D G3DSA:3.30.2320.30 100 203 6.4E-24 T 23-10-2018 IPR038495 V-type ATPase subunit E, C-terminal domain superfamily Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A0127_05855 28e01246e697b41bb2d3bdcd43da3fd7 280 SUPERFAMILY SSF103481 182 276 3.66E-12 T 23-10-2018 A0127_05855 28e01246e697b41bb2d3bdcd43da3fd7 280 Pfam PF00892 EamA-like transporter family 149 273 1.2E-16 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A0127_05855 28e01246e697b41bb2d3bdcd43da3fd7 280 Pfam PF00892 EamA-like transporter family 7 140 3.8E-13 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A0127_05855 28e01246e697b41bb2d3bdcd43da3fd7 280 SUPERFAMILY SSF103481 42 142 1.03E-9 T 23-10-2018 A0127_01950 652d6152b9a5866352e52b88e32c356b 333 SUPERFAMILY SSF52283 1 131 2.65E-33 T 23-10-2018 A0127_01950 652d6152b9a5866352e52b88e32c356b 333 Gene3D G3DSA:3.40.50.720 95 286 4.7E-111 T 23-10-2018 A0127_01950 652d6152b9a5866352e52b88e32c356b 333 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 106 286 1.8E-53 T 23-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 A0127_01950 652d6152b9a5866352e52b88e32c356b 333 Gene3D G3DSA:3.40.50.720 16 318 4.7E-111 T 23-10-2018 A0127_01950 652d6152b9a5866352e52b88e32c356b 333 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 149 176 - T 23-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 A0127_01950 652d6152b9a5866352e52b88e32c356b 333 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 5 318 7.4E-35 T 23-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 A0127_01950 652d6152b9a5866352e52b88e32c356b 333 SUPERFAMILY SSF51735 98 287 4.97E-50 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A0127_01460 3f954adfb3997a40b478c4f9e2c36acf 209 SUPERFAMILY SSF53335 7 182 7.1E-36 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A0127_01460 3f954adfb3997a40b478c4f9e2c36acf 209 Pfam PF08241 Methyltransferase domain 44 128 1.1E-20 T 23-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 A0127_01460 3f954adfb3997a40b478c4f9e2c36acf 209 Gene3D G3DSA:3.40.50.150 2 209 1.3E-64 T 23-10-2018 A0127_02380 6f7139cf2bf1035d1276b2fbd4482473 170 Gene3D G3DSA:3.30.300.20 47 97 2.8E-8 T 23-10-2018 IPR015946 K homology domain-like, alpha/beta A0127_02380 6f7139cf2bf1035d1276b2fbd4482473 170 SUPERFAMILY SSF54814 39 96 7.85E-9 T 23-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 A0127_02380 6f7139cf2bf1035d1276b2fbd4482473 170 SMART SM00322 57 158 0.0019 T 23-10-2018 IPR004087 K Homology domain GO:0003676 A0127_02380 6f7139cf2bf1035d1276b2fbd4482473 170 Pfam PF13184 NusA-like KH domain 57 124 9.8E-10 T 23-10-2018 IPR025249 KH domain, NusA-like GO:0003723 A0127_06505 87b1b3f7bfbd51e8ae68da9ad6f00b01 294 Gene3D G3DSA:3.90.550.10 2 228 3.3E-52 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A0127_06505 87b1b3f7bfbd51e8ae68da9ad6f00b01 294 Pfam PF00535 Glycosyl transferase family 2 5 163 8.3E-28 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A0127_06505 87b1b3f7bfbd51e8ae68da9ad6f00b01 294 SUPERFAMILY SSF53448 2 207 2.33E-38 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A0127_02665 1f47e9d38622a9a01eab566a879616bb 514 TIGRFAM TIGR00284 TIGR00284: dihydropteroate synthase-related protein 4 502 3.7E-97 T 23-10-2018 IPR005236 Dihydropteroate synthase-related protein synthase-related protein A0127_02665 1f47e9d38622a9a01eab566a879616bb 514 SUPERFAMILY SSF51717 167 384 3.79E-24 T 23-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A0127_10140 9733ea77d90cbfe8ba66c043d1236900 247 Gene3D G3DSA:3.40.50.150 12 246 1.4E-27 T 23-10-2018 A0127_10140 9733ea77d90cbfe8ba66c043d1236900 247 Pfam PF13847 Methyltransferase domain 70 201 3.4E-13 T 23-10-2018 IPR025714 Methyltransferase domain A0127_10140 9733ea77d90cbfe8ba66c043d1236900 247 SUPERFAMILY SSF53335 29 223 2.52E-25 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A0127_04145 c4fb8a52d53026287f4ebe46b6cdea6d 304 SUPERFAMILY SSF109755 125 301 1.7E-17 T 23-10-2018 A0127_04145 c4fb8a52d53026287f4ebe46b6cdea6d 304 Gene3D G3DSA:1.20.58.220 134 235 4.8E-11 T 23-10-2018 IPR038078 PhoU-like domain superfamily A0127_04145 c4fb8a52d53026287f4ebe46b6cdea6d 304 Pfam PF01895 PhoU domain 138 230 1.2E-12 T 23-10-2018 IPR026022 PhoU domain A0127_04145 c4fb8a52d53026287f4ebe46b6cdea6d 304 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 8 50 3.5E-8 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 A0127_04145 c4fb8a52d53026287f4ebe46b6cdea6d 304 SMART SM00966 8 54 1.3E-9 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 A0127_02530 80bb28eaf9bd0ec1835b0c6886d2d5bc 708 Pfam PF10633 NPCBM-associated, NEW3 domain of alpha-galactosidase 596 663 6.6E-6 T 23-10-2018 IPR018905 Alpha-galactosidase, NEW3 domain A0127_02530 80bb28eaf9bd0ec1835b0c6886d2d5bc 708 Gene3D G3DSA:2.60.40.1120 381 453 1.4E-6 T 23-10-2018 A0127_03935 b60931f9c0c3bcacd39a8cc132cdb2ad 164 Gene3D G3DSA:3.60.21.10 1 163 3.8E-41 T 23-10-2018 IPR029052 Metallo-dependent phosphatase-like A0127_03935 b60931f9c0c3bcacd39a8cc132cdb2ad 164 TIGRFAM TIGR00040 yfcE: phosphodiesterase, MJ0936 family 2 156 7.7E-36 T 23-10-2018 IPR000979 Phosphodiesterase MJ0936/Vps29 Reactome: R-HSA-3238698 A0127_03935 b60931f9c0c3bcacd39a8cc132cdb2ad 164 SUPERFAMILY SSF56300 2 163 4.27E-38 T 23-10-2018 A0127_03935 b60931f9c0c3bcacd39a8cc132cdb2ad 164 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 2 152 3.3E-30 T 23-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 A0127_03270 308b85118a710fcf7bec22edaec66056 538 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 33 435 5.4E-78 T 23-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 A0127_03270 308b85118a710fcf7bec22edaec66056 538 Pfam PF00474 Sodium:solute symporter family 33 435 1.6E-84 T 23-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 A0127_03270 308b85118a710fcf7bec22edaec66056 538 Gene3D G3DSA:1.20.1730.10 22 515 4.9E-93 T 23-10-2018 IPR038377 Sodium/glucose symporter superfamily A0127_08455 2cd0eb1bb5a0f32d63d842fdd3a4f4fb 139 SUPERFAMILY SSF141322 77 139 7.06E-20 T 23-10-2018 A0127_08455 2cd0eb1bb5a0f32d63d842fdd3a4f4fb 139 Pfam PF01957 NfeD-like C-terminal, partner-binding 8 138 5.3E-15 T 23-10-2018 IPR002810 NfeD-like, C-terminal domain A0127_08455 2cd0eb1bb5a0f32d63d842fdd3a4f4fb 139 Gene3D G3DSA:2.40.50.140 69 139 2.3E-19 T 23-10-2018 A0127_08645 a1aa26565f2815e41b82f07c9c7ddc59 355 SMART SM00981 60 149 9.9E-23 T 23-10-2018 IPR004114 THUMP domain GO:0003723 A0127_08645 a1aa26565f2815e41b82f07c9c7ddc59 355 Pfam PF02926 THUMP domain 33 148 1.1E-28 T 23-10-2018 IPR004114 THUMP domain GO:0003723 A0127_08645 a1aa26565f2815e41b82f07c9c7ddc59 355 Gene3D G3DSA:3.30.2130.30 1 150 3.5E-23 T 23-10-2018 A0127_08645 a1aa26565f2815e41b82f07c9c7ddc59 355 SUPERFAMILY SSF75217 189 336 9.94E-22 T 23-10-2018 IPR029028 Alpha/beta knot methyltransferases A0127_08645 a1aa26565f2815e41b82f07c9c7ddc59 355 SUPERFAMILY SSF143437 7 147 4.71E-27 T 23-10-2018 A0127_08645 a1aa26565f2815e41b82f07c9c7ddc59 355 Pfam PF14419 AF2226-like SPOUT RNA Methylase fused to THUMP 169 342 4.8E-84 T 23-10-2018 IPR025849 AF2226-like SPOUT RNA methylase fused to THUMP A0127_05470 7c8a674718a7ef52705af957f04c2f50 141 SUPERFAMILY SSF54690 3 135 2.88E-48 T 23-10-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 A0127_05470 7c8a674718a7ef52705af957f04c2f50 141 Gene3D G3DSA:3.90.1170.40 1 136 2.7E-52 T 23-10-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 A0127_05470 7c8a674718a7ef52705af957f04c2f50 141 Pfam PF02391 MoaE protein 5 117 1.3E-39 T 23-10-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 A0127_03440 1f831f48b51e4bb170a8458b40d40c64 291 SUPERFAMILY SSF52343 90 257 1.65E-13 T 23-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A0127_03440 1f831f48b51e4bb170a8458b40d40c64 291 Gene3D G3DSA:3.40.50.80 101 212 3.5E-17 T 23-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain A0127_03440 1f831f48b51e4bb170a8458b40d40c64 291 SUPERFAMILY SSF63380 2 94 1.3E-17 T 23-10-2018 IPR017938 Riboflavin synthase-like beta-barrel A0127_03440 1f831f48b51e4bb170a8458b40d40c64 291 PIRSF PIRSF006816 1 264 4.7E-56 T 23-10-2018 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 A0127_03440 1f831f48b51e4bb170a8458b40d40c64 291 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 222 258 3.8E-10 T 23-10-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain A0127_03440 1f831f48b51e4bb170a8458b40d40c64 291 Gene3D G3DSA:2.40.30.10 1 93 2.6E-17 T 23-10-2018 A0127_06570 56f3aeebd7064a8ccca97ee7299730c0 156 SMART SM00670 4 133 8.9E-7 T 23-10-2018 IPR002716 PIN domain A0127_06570 56f3aeebd7064a8ccca97ee7299730c0 156 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 6 142 9.751 T 23-10-2018 IPR022907 VapC family GO:0004540 A0127_06570 56f3aeebd7064a8ccca97ee7299730c0 156 Pfam PF01850 PIN domain 7 134 8.3E-20 T 23-10-2018 IPR002716 PIN domain A0127_06570 56f3aeebd7064a8ccca97ee7299730c0 156 Gene3D G3DSA:3.40.50.1010 4 143 3.0E-7 T 23-10-2018 A0127_06570 56f3aeebd7064a8ccca97ee7299730c0 156 SUPERFAMILY SSF88723 7 143 3.92E-15 T 23-10-2018 IPR029060 PIN-like domain superfamily A0127_06865 9c0622e3c9baa70993cbc24b7d1ec7e2 173 Pfam PF01613 Flavin reductase like domain 6 135 1.7E-22 T 23-10-2018 IPR002563 Flavin reductase like domain GO:0010181 A0127_06865 9c0622e3c9baa70993cbc24b7d1ec7e2 173 Gene3D G3DSA:2.30.110.10 1 161 1.4E-45 T 23-10-2018 IPR012349 FMN-binding split barrel GO:0048037 A0127_06865 9c0622e3c9baa70993cbc24b7d1ec7e2 173 SMART SM00903 3 141 4.7E-18 T 23-10-2018 IPR002563 Flavin reductase like domain GO:0010181 A0127_06865 9c0622e3c9baa70993cbc24b7d1ec7e2 173 SUPERFAMILY SSF50475 1 160 1.03E-38 T 23-10-2018 A0127_05110 2f759f221744a8ac6e10ec8d53fc3b51 195 PIRSF PIRSF006380 1 195 6.3E-70 T 23-10-2018 IPR002802 Protein of unknown function DUF99 A0127_05110 2f759f221744a8ac6e10ec8d53fc3b51 195 Gene3D G3DSA:3.30.2170.10 3 195 1.4E-61 T 23-10-2018 A0127_05110 2f759f221744a8ac6e10ec8d53fc3b51 195 ProDom PD016744 UPF0215 ST0304 TK2033 MA4269 PAE0952 SSO0256 NEQ431 MK0057 PTO0905 TV0037 72 184 1.0E-53 T 23-10-2018 IPR002802 Protein of unknown function DUF99 A0127_05110 2f759f221744a8ac6e10ec8d53fc3b51 195 Pfam PF01949 Protein of unknown function DUF99 8 188 3.4E-65 T 23-10-2018 IPR002802 Protein of unknown function DUF99 A0127_05110 2f759f221744a8ac6e10ec8d53fc3b51 195 Hamap MF_00582 UPF0215 protein . 9 189 34.116 T 23-10-2018 IPR002802 Protein of unknown function DUF99 A0127_07905 213208d978f48c7db62d0c7faa3f9707 151 Gene3D G3DSA:3.30.1440.10 3 149 4.8E-45 T 23-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_07905 213208d978f48c7db62d0c7faa3f9707 151 Pfam PF01877 RNA binding 9 131 3.3E-38 T 23-10-2018 IPR002739 Uncharacterised protein family UPF0201 A0127_07905 213208d978f48c7db62d0c7faa3f9707 151 SUPERFAMILY SSF55282 7 149 2.06E-42 T 23-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_09570 3cc034461234a2d1a068c28a6707787a 244 Pfam PF01925 Sulfite exporter TauE/SafE 8 239 2.1E-41 T 23-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 A0127_09680 90236f748a7b95e05e5e50b651787613 189 SUPERFAMILY SSF51182 2 188 8.65E-44 T 23-10-2018 IPR011051 RmlC-like cupin domain superfamily A0127_09680 90236f748a7b95e05e5e50b651787613 189 Pfam PF06560 Glucose-6-phosphate isomerase (GPI) 25 182 1.3E-40 T 23-10-2018 IPR010551 Glucose-6-phosphate isomerase, prokaryote GO:0004347|GO:0005737|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385 A0127_09680 90236f748a7b95e05e5e50b651787613 189 Gene3D G3DSA:2.60.120.10 1 189 4.3E-75 T 23-10-2018 IPR014710 RmlC-like jelly roll fold A0127_09680 90236f748a7b95e05e5e50b651787613 189 PIRSF PIRSF019325 1 189 1.2E-74 T 23-10-2018 IPR016758 Glucose-6-phosphate isomerase, archaea/bacteria GO:0004347|GO:0005506 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385 A0127_03960 631ad71ac36dc1724b5a1e844ad4dddb 118 SUPERFAMILY SSF64076 2 118 1.44E-35 T 23-10-2018 IPR036748 MTH938-like superfamily A0127_03960 631ad71ac36dc1724b5a1e844ad4dddb 118 Gene3D G3DSA:3.40.1230.10 1 118 1.9E-36 T 23-10-2018 IPR036748 MTH938-like superfamily A0127_03960 631ad71ac36dc1724b5a1e844ad4dddb 118 Pfam PF04430 Protein of unknown function (DUF498/DUF598) 8 114 2.5E-11 T 23-10-2018 IPR007523 NDUFAF3/Mth938 domain-containing protein A0127_10265 523eafd8cd17fb96829a3a84212bf7ad 302 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 235 293 2.0E-6 T 23-10-2018 IPR002831 Transcription regulator TrmB, N-terminal A0127_10265 523eafd8cd17fb96829a3a84212bf7ad 302 Gene3D G3DSA:1.10.10.10 223 301 3.4E-10 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A0127_10265 523eafd8cd17fb96829a3a84212bf7ad 302 SUPERFAMILY SSF46785 228 294 1.53E-11 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A0127_09280 2b3b93ee1cb2ae35bc09ab9afa02fbc1 382 Gene3D G3DSA:3.40.50.920 272 381 2.3E-25 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A0127_09280 2b3b93ee1cb2ae35bc09ab9afa02fbc1 382 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 22 253 5.8E-80 T 23-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 A0127_09280 2b3b93ee1cb2ae35bc09ab9afa02fbc1 382 SUPERFAMILY SSF52518 12 263 7.36E-71 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold A0127_09280 2b3b93ee1cb2ae35bc09ab9afa02fbc1 382 Gene3D G3DSA:3.40.50.970 1 199 3.1E-84 T 23-10-2018 A0127_09280 2b3b93ee1cb2ae35bc09ab9afa02fbc1 382 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 282 376 2.1E-21 T 23-10-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II A0127_09280 2b3b93ee1cb2ae35bc09ab9afa02fbc1 382 SUPERFAMILY SSF52922 274 378 1.01E-26 T 23-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 A0127_06525 30bc1737a502e9064fde27004b3f15ac 361 Pfam PF00535 Glycosyl transferase family 2 7 59 3.2E-10 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A0127_06525 30bc1737a502e9064fde27004b3f15ac 361 SUPERFAMILY SSF53448 1 332 1.2E-52 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A0127_06525 30bc1737a502e9064fde27004b3f15ac 361 Pfam PF13641 Glycosyltransferase like family 2 117 269 6.3E-8 T 23-10-2018 A0127_08465 e430814196abdd9b15a4795aafd35552 51 Hamap MF_00629 50S ribosomal protein L39e [rpl39e]. 1 51 19.338 T 23-10-2018 IPR000077 Ribosomal protein L39e GO:0003735|GO:0005622|GO:0005840|GO:0006412 A0127_08465 e430814196abdd9b15a4795aafd35552 51 Gene3D G3DSA:1.10.1620.10 2 51 2.1E-20 T 23-10-2018 IPR023626 Ribosomal protein L39e domain superfamily A0127_08465 e430814196abdd9b15a4795aafd35552 51 ProSitePatterns PS00051 Ribosomal protein L39e signature. 30 46 - T 23-10-2018 IPR020083 Ribosomal protein L39e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_08465 e430814196abdd9b15a4795aafd35552 51 SUPERFAMILY SSF48662 4 50 6.41E-20 T 23-10-2018 IPR023626 Ribosomal protein L39e domain superfamily A0127_08465 e430814196abdd9b15a4795aafd35552 51 Pfam PF00832 Ribosomal L39 protein 9 50 9.0E-23 T 23-10-2018 IPR000077 Ribosomal protein L39e GO:0003735|GO:0005622|GO:0005840|GO:0006412 A0127_08800 61ff5768d5897454d5aebc44f3d6a3f0 84 Pfam PF04066 Multiple resistance and pH regulation protein F (MrpF / PhaF) 29 81 1.6E-19 T 23-10-2018 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 A0127_09075 6b499523672620e300d3cec7ed39bed7 224 Pfam PF15517 TBP-interacting protein N-terminus 2 100 2.3E-50 T 23-10-2018 IPR029125 TBP-interacting protein, N-terminal A0127_09075 6b499523672620e300d3cec7ed39bed7 224 SUPERFAMILY SSF159612 1 217 2.09E-113 T 23-10-2018 A0127_09075 6b499523672620e300d3cec7ed39bed7 224 Gene3D G3DSA:3.40.1350.70 1 98 2.5E-61 T 23-10-2018 IPR038230 TBP-interacting protein, N-terminal superfamily A0127_09075 6b499523672620e300d3cec7ed39bed7 224 Gene3D G3DSA:3.90.79.30 99 218 4.3E-74 T 23-10-2018 A0127_04820 0bbe2931e52999c76e46f2f8d4784403 531 Pfam PF03553 Na+/H+ antiporter family 158 486 1.4E-74 T 23-10-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 A0127_07140 d04caa6c30ed56bbf41395f4db04cdfd 246 Gene3D G3DSA:3.40.50.700 3 163 2.4E-36 T 23-10-2018 IPR037024 [NiFe]-hydrogenase, small subunit, N-terminal domain superfamily A0127_07140 d04caa6c30ed56bbf41395f4db04cdfd 246 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 15 150 1.7E-24 T 23-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A0127_07140 d04caa6c30ed56bbf41395f4db04cdfd 246 SUPERFAMILY SSF56770 3 211 3.4E-43 T 23-10-2018 A0127_00925 7303223f60635632e4d2b6b0e217d290 320 SUPERFAMILY SSF69572 5 308 1.57E-63 T 23-10-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 A0127_00925 7303223f60635632e4d2b6b0e217d290 320 Pfam PF00899 ThiF family 6 226 2.7E-43 T 23-10-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 A0127_00925 7303223f60635632e4d2b6b0e217d290 320 Gene3D G3DSA:3.40.50.720 3 233 5.3E-57 T 23-10-2018 A0127_09820 0df8d312b06bf6035f5f84b481a626dc 391 Pfam PF04998 RNA polymerase Rpb1, domain 5 50 332 1.5E-55 T 23-10-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A0127_09820 0df8d312b06bf6035f5f84b481a626dc 391 Hamap MF_00411 DNA-directed RNA polymerase subunit A'' [rpoA2]. 3 385 41.146 T 23-10-2018 IPR012757 DNA-directed RNA polymerase subunit A'' GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A0127_09820 0df8d312b06bf6035f5f84b481a626dc 391 SUPERFAMILY SSF64484 31 384 4.35E-105 T 23-10-2018 A0127_09820 0df8d312b06bf6035f5f84b481a626dc 391 Gene3D G3DSA:1.10.150.390 333 378 1.6E-22 T 23-10-2018 A0127_09820 0df8d312b06bf6035f5f84b481a626dc 391 TIGRFAM TIGR02389 RNA_pol_rpoA2: DNA-directed RNA polymerase, subunit A'' 21 382 6.9E-150 T 23-10-2018 IPR012757 DNA-directed RNA polymerase subunit A'' GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 A0127_04840 e552033b9cb66a9c40c32f054cc703f9 185 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 185 28.397 T 23-10-2018 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A0127_04840 e552033b9cb66a9c40c32f054cc703f9 185 Pfam PF00156 Phosphoribosyl transferase domain 39 159 3.8E-22 T 23-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 A0127_04840 e552033b9cb66a9c40c32f054cc703f9 185 SUPERFAMILY SSF53271 6 164 1.97E-46 T 23-10-2018 IPR029057 Phosphoribosyltransferase-like A0127_04840 e552033b9cb66a9c40c32f054cc703f9 185 TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase 13 174 4.2E-53 T 23-10-2018 IPR004467 Orotate phosphoribosyl transferase domain GO:0004588 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 A0127_04840 e552033b9cb66a9c40c32f054cc703f9 185 Gene3D G3DSA:3.40.50.2020 1 179 1.7E-60 T 23-10-2018 A0127_04565 e5819d812bd14bf1f97f68cfcc1e02b1 112 Pfam PF01906 Putative heavy-metal-binding 7 109 1.8E-35 T 23-10-2018 IPR002765 Uncharacterised protein family UPF0145 A0127_04565 e5819d812bd14bf1f97f68cfcc1e02b1 112 Hamap MF_00338 UPF0145 protein YbjQ [ybjQ]. 7 109 24.799 T 23-10-2018 IPR002765 Uncharacterised protein family UPF0145 A0127_04565 e5819d812bd14bf1f97f68cfcc1e02b1 112 SUPERFAMILY SSF117782 7 111 4.58E-35 T 23-10-2018 IPR035439 UPF0145 domain superfamily A0127_04565 e5819d812bd14bf1f97f68cfcc1e02b1 112 Gene3D G3DSA:3.30.110.70 7 112 2.0E-30 T 23-10-2018 A0127_05835 8a03acbe0ca2718d9f663a1f69ec123d 447 SUPERFAMILY SSF46785 231 309 6.69E-7 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A0127_05835 8a03acbe0ca2718d9f663a1f69ec123d 447 SUPERFAMILY SSF52540 2 232 2.43E-35 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_05835 8a03acbe0ca2718d9f663a1f69ec123d 447 Gene3D G3DSA:3.40.50.300 57 160 1.0E-14 T 23-10-2018 A0127_05835 8a03acbe0ca2718d9f663a1f69ec123d 447 Pfam PF01637 ATPase domain predominantly from Archaea 4 194 7.1E-25 T 23-10-2018 IPR011579 ATPase domain GO:0005524 A0127_05835 8a03acbe0ca2718d9f663a1f69ec123d 447 Pfam PF03008 Archaea bacterial proteins of unknown function 300 396 1.1E-31 T 23-10-2018 IPR004256 Domain of unknown function DUF234, DEXX-box ATPase C-terminal A0127_00340 58e32848f49c0860e7b64fbd8232c51c 121 Pfam PF09685 Domain of unknown function (DUF4870) 27 108 2.8E-7 T 23-10-2018 IPR019109 Protein of unknown function DUF4870 A0127_00185 1de1bd3a4dece0e74a0dd8a5f01e536c 429 PRINTS PR00173 Glutamate-aspartate symporter signature 304 330 2.1E-48 T 23-10-2018 A0127_00185 1de1bd3a4dece0e74a0dd8a5f01e536c 429 PRINTS PR00173 Glutamate-aspartate symporter signature 339 358 2.1E-48 T 23-10-2018 A0127_00185 1de1bd3a4dece0e74a0dd8a5f01e536c 429 PRINTS PR00173 Glutamate-aspartate symporter signature 55 75 2.1E-48 T 23-10-2018 A0127_00185 1de1bd3a4dece0e74a0dd8a5f01e536c 429 PRINTS PR00173 Glutamate-aspartate symporter signature 203 222 2.1E-48 T 23-10-2018 A0127_00185 1de1bd3a4dece0e74a0dd8a5f01e536c 429 PRINTS PR00173 Glutamate-aspartate symporter signature 12 32 2.1E-48 T 23-10-2018 A0127_00185 1de1bd3a4dece0e74a0dd8a5f01e536c 429 PRINTS PR00173 Glutamate-aspartate symporter signature 366 386 2.1E-48 T 23-10-2018 A0127_00185 1de1bd3a4dece0e74a0dd8a5f01e536c 429 PRINTS PR00173 Glutamate-aspartate symporter signature 84 109 2.1E-48 T 23-10-2018 A0127_00185 1de1bd3a4dece0e74a0dd8a5f01e536c 429 ProSitePatterns PS00713 Sodium:dicarboxylate symporter family signature 1. 47 62 - T 23-10-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site A0127_00185 1de1bd3a4dece0e74a0dd8a5f01e536c 429 SUPERFAMILY SSF118215 15 420 3.14E-122 T 23-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 A0127_00185 1de1bd3a4dece0e74a0dd8a5f01e536c 429 Pfam PF00375 Sodium:dicarboxylate symporter family 15 418 6.7E-127 T 23-10-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 A0127_00185 1de1bd3a4dece0e74a0dd8a5f01e536c 429 Gene3D G3DSA:1.10.3860.10 1 429 1.2E-179 T 23-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 A0127_03920 be1c6de2993e22944565fd6b9d39c47a 198 SMART SM00418 9 89 9.8E-18 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A0127_03920 be1c6de2993e22944565fd6b9d39c47a 198 Pfam PF01022 Bacterial regulatory protein, arsR family 16 61 5.6E-14 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A0127_03920 be1c6de2993e22944565fd6b9d39c47a 198 Gene3D G3DSA:1.10.10.10 4 105 4.0E-28 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A0127_03920 be1c6de2993e22944565fd6b9d39c47a 198 SUPERFAMILY SSF46785 7 174 9.27E-29 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A0127_03895 601feb42ba9b23b5064c0a895575eee2 264 Gene3D G3DSA:3.20.20.70 20 259 9.4E-6 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A0127_03895 601feb42ba9b23b5064c0a895575eee2 264 SUPERFAMILY SSF102114 29 219 1.69E-7 T 23-10-2018 A0127_03895 601feb42ba9b23b5064c0a895575eee2 264 Pfam PF04055 Radical SAM superfamily 27 181 2.1E-9 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A0127_01305 92cc94cc6ebcb040c760921a98b6c352 167 ProDom PD010896 FAMILY DUF88 ARCHAEBACTERIAL PROTEIN MJ0482 PH0073 PF2040 VNG1608C MA3857 PF2039 32 104 8.0E-33 T 23-10-2018 A0127_01305 92cc94cc6ebcb040c760921a98b6c352 167 Pfam PF01936 NYN domain 31 161 2.6E-18 T 23-10-2018 IPR021139 NYN domain, limkain-b1-type A0127_01305 92cc94cc6ebcb040c760921a98b6c352 167 TIGRFAM TIGR00288 TIGR00288: TIGR00288 family protein 22 166 2.0E-63 T 23-10-2018 IPR002790 Conserved hypothetical protein CHP00288 A0127_01305 92cc94cc6ebcb040c760921a98b6c352 167 Gene3D G3DSA:3.40.50.1010 22 164 9.7E-9 T 23-10-2018 A0127_06285 ed915d9dc4f5a742660af56e8a030031 623 Pfam PF03235 Protein of unknown function DUF262 13 278 1.0E-31 T 23-10-2018 IPR004919 Domain of unknown function DUF262 A0127_00795 49cbd16d37813c3857709db6914d7e17 341 Pfam PF04283 Chemotaxis signal transduction system protein F from archaea 13 227 4.0E-13 T 23-10-2018 IPR007381 Chemotaxis signal transduction system protein F A0127_00795 49cbd16d37813c3857709db6914d7e17 341 Gene3D G3DSA:1.10.10.10 245 340 1.5E-6 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A0127_00795 49cbd16d37813c3857709db6914d7e17 341 SUPERFAMILY SSF46785 251 335 2.21E-5 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A0127_03600 c3dfe14b88a6514bb7b368d9feae5302 234 Gene3D G3DSA:1.10.150.240 15 100 1.8E-62 T 23-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 A0127_03600 c3dfe14b88a6514bb7b368d9feae5302 234 Pfam PF13419 Haloacid dehalogenase-like hydrolase 4 200 1.3E-28 T 23-10-2018 A0127_03600 c3dfe14b88a6514bb7b368d9feae5302 234 SUPERFAMILY SSF56784 1 230 1.73E-50 T 23-10-2018 IPR036412 HAD-like superfamily A0127_03600 c3dfe14b88a6514bb7b368d9feae5302 234 Gene3D G3DSA:3.40.50.1000 3 222 1.8E-62 T 23-10-2018 IPR023214 HAD superfamily A0127_03600 c3dfe14b88a6514bb7b368d9feae5302 234 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 1 12 1.1E-12 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A0127_03600 c3dfe14b88a6514bb7b368d9feae5302 234 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 114 127 1.1E-12 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A0127_03600 c3dfe14b88a6514bb7b368d9feae5302 234 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 145 161 1.1E-12 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A0127_03600 c3dfe14b88a6514bb7b368d9feae5302 234 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 163 183 1.1E-12 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A0127_03600 c3dfe14b88a6514bb7b368d9feae5302 234 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 104 201 1.3E-8 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A0127_03600 c3dfe14b88a6514bb7b368d9feae5302 234 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 100 195 1.2E-12 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A0127_03600 c3dfe14b88a6514bb7b368d9feae5302 234 TIGRFAM TIGR02253 CTE7: HAD hydrolase, TIGR02253 family 2 226 9.6E-60 T 23-10-2018 IPR011950 HAD-superfamily hydrolase, subfamily IA, CTE7 GO:0016787 Reactome: R-HSA-4085001 A0127_05305 6ed7d283dfb3fb087067f70d8b12d59f 123 TIGRFAM TIGR01300 CPA3_mnhG_phaG: monovalent cation/proton antiporter, MnhG/PhaG subunit 11 114 6.5E-34 T 23-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 A0127_05305 6ed7d283dfb3fb087067f70d8b12d59f 123 Pfam PF03334 Na+/H+ antiporter subunit 11 100 3.1E-23 T 23-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 A0127_09720 dc726bf8c6c22e56182387c27728ef6d 59 Hamap MF_00803 Ribosome biogenesis protein Nop10 [nop10]. 3 53 21.365 T 23-10-2018 IPR023532 H/ACA ribonucleoprotein complex subunit Nop10 , archaeal-type GO:0001522|GO:0030515|GO:0042254 A0127_09720 dc726bf8c6c22e56182387c27728ef6d 59 Gene3D G3DSA:2.20.28.40 1 59 3.3E-31 T 23-10-2018 IPR036756 H/ACA ribonucleoprotein complex, subunit Nop10 superfamily GO:0001522|GO:0030515|GO:0042254 Reactome: R-HSA-6790901 A0127_09720 dc726bf8c6c22e56182387c27728ef6d 59 SUPERFAMILY SSF144210 4 51 2.49E-22 T 23-10-2018 IPR036756 H/ACA ribonucleoprotein complex, subunit Nop10 superfamily GO:0001522|GO:0030515|GO:0042254 Reactome: R-HSA-6790901 A0127_09720 dc726bf8c6c22e56182387c27728ef6d 59 Pfam PF04135 Nucleolar RNA-binding protein, Nop10p family 1 51 2.1E-28 T 23-10-2018 IPR007264 H/ACA ribonucleoprotein complex, subunit Nop10 GO:0001522|GO:0030515|GO:0042254 Reactome: R-HSA-6790901 A0127_02770 313a6f49a505ec9bef14eeccd7449208 389 Gene3D G3DSA:1.20.1250.20 6 382 2.9E-34 T 23-10-2018 A0127_02770 313a6f49a505ec9bef14eeccd7449208 389 SUPERFAMILY SSF103473 12 385 7.98E-35 T 23-10-2018 IPR036259 MFS transporter superfamily A0127_02770 313a6f49a505ec9bef14eeccd7449208 389 Pfam PF07690 Major Facilitator Superfamily 17 350 2.1E-21 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A0127_01250 2e46494cefcb0d32c4637a7ea8817ea9 865 SMART SM00490 300 386 4.8E-17 T 23-10-2018 IPR001650 Helicase, C-terminal A0127_01250 2e46494cefcb0d32c4637a7ea8817ea9 865 PIRSF PIRSF037307 5 863 1.9E-289 T 23-10-2018 IPR017170 Lhr-like ATP-dependent RNA helicase, predicted GO:0005524|GO:0016818 A0127_01250 2e46494cefcb0d32c4637a7ea8817ea9 865 SUPERFAMILY SSF52540 47 390 3.5E-46 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_01250 2e46494cefcb0d32c4637a7ea8817ea9 865 Pfam PF00271 Helicase conserved C-terminal domain 275 382 1.2E-15 T 23-10-2018 IPR001650 Helicase, C-terminal A0127_01250 2e46494cefcb0d32c4637a7ea8817ea9 865 Gene3D G3DSA:3.40.50.300 14 235 2.9E-52 T 23-10-2018 A0127_01250 2e46494cefcb0d32c4637a7ea8817ea9 865 SMART SM00487 31 257 6.9E-33 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A0127_01250 2e46494cefcb0d32c4637a7ea8817ea9 865 Pfam PF00270 DEAD/DEAH box helicase 36 223 5.6E-27 T 23-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 A0127_01250 2e46494cefcb0d32c4637a7ea8817ea9 865 Gene3D G3DSA:3.40.50.300 259 418 2.0E-24 T 23-10-2018 A0127_01250 2e46494cefcb0d32c4637a7ea8817ea9 865 Pfam PF08494 DEAD/H associated 640 828 7.9E-55 T 23-10-2018 IPR013701 DEAD/H associated GO:0005524|GO:0016818 A0127_09315 94932fb6ba730b0acf6ec537870a476f 131 Gene3D G3DSA:1.10.260.40 16 71 2.5E-6 T 23-10-2018 A0127_09315 94932fb6ba730b0acf6ec537870a476f 131 SUPERFAMILY SSF47413 17 53 1.52E-5 T 23-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 A0127_09315 94932fb6ba730b0acf6ec537870a476f 131 Pfam PF01022 Bacterial regulatory protein, arsR family 17 51 6.4E-5 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A0127_05950 9580dbc2de67d959babce08c80d7b7c4 278 Pfam PF13559 Domain of unknown function (DUF4129) 201 262 3.4E-5 T 23-10-2018 IPR025403 Domain of unknown function DUF4129 A0127_04090 dc5f713569df99d0314b68d3a1b6ffc6 127 Pfam PF10066 Uncharacterized conserved protein (DUF2304) 5 108 1.7E-25 T 23-10-2018 IPR019277 Protein of unknown function DUF2304 A0127_05440 56e694eb4092dce625ecd35ebf2a995d 279 Gene3D G3DSA:3.20.20.70 9 224 4.6E-17 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A0127_05440 56e694eb4092dce625ecd35ebf2a995d 279 SMART SM00729 17 220 1.0E-5 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A0127_05440 56e694eb4092dce625ecd35ebf2a995d 279 SUPERFAMILY SSF102114 17 241 6.41E-29 T 23-10-2018 A0127_05440 56e694eb4092dce625ecd35ebf2a995d 279 Pfam PF04055 Radical SAM superfamily 24 163 4.0E-9 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A0127_02855 0af370ccd1f4b616a512fe2c2082ac2d 402 Gene3D G3DSA:1.20.1250.20 5 380 4.7E-29 T 23-10-2018 A0127_02855 0af370ccd1f4b616a512fe2c2082ac2d 402 SUPERFAMILY SSF103473 10 377 7.46E-31 T 23-10-2018 IPR036259 MFS transporter superfamily A0127_02855 0af370ccd1f4b616a512fe2c2082ac2d 402 Pfam PF07690 Major Facilitator Superfamily 11 348 6.1E-16 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A0127_00205 9b904bf661251a9f49fd9d26523f8848 696 TIGRFAM TIGR01587 cas3_core: CRISPR-associated helicase Cas3 230 551 8.6E-69 T 23-10-2018 IPR006474 Helicase Cas3, CRISPR-associated, core A0127_00205 9b904bf661251a9f49fd9d26523f8848 696 SMART SM00490 439 517 1.9E-9 T 23-10-2018 IPR001650 Helicase, C-terminal A0127_00205 9b904bf661251a9f49fd9d26523f8848 696 Gene3D G3DSA:3.40.50.300 205 386 3.4E-8 T 23-10-2018 A0127_00205 9b904bf661251a9f49fd9d26523f8848 696 Gene3D G3DSA:1.10.3210.30 8 204 2.2E-9 T 23-10-2018 IPR038257 CRISPR-associated Cas3-type HD domain superfamily A0127_00205 9b904bf661251a9f49fd9d26523f8848 696 Gene3D G3DSA:3.40.50.300 389 556 2.4E-18 T 23-10-2018 A0127_00205 9b904bf661251a9f49fd9d26523f8848 696 Pfam PF00271 Helicase conserved C-terminal domain 421 517 2.1E-7 T 23-10-2018 IPR001650 Helicase, C-terminal A0127_00205 9b904bf661251a9f49fd9d26523f8848 696 SMART SM00487 208 408 5.9E-4 T 23-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain A0127_00205 9b904bf661251a9f49fd9d26523f8848 696 TIGRFAM TIGR01596 cas3_HD: CRISPR-associated endonuclease Cas3-HD 22 183 2.5E-17 T 23-10-2018 IPR006483 CRISPR-associated Cas3-type HD domain A0127_00205 9b904bf661251a9f49fd9d26523f8848 696 SUPERFAMILY SSF52540 224 528 9.02E-28 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_01625 b75e7e531f8fb727ef96364e97d1130a 594 Pfam PF16286 Domain of unknown function (DUF4932) 28 203 3.9E-10 T 23-10-2018 IPR032560 Protein of unknown function DUF4932 A0127_01625 b75e7e531f8fb727ef96364e97d1130a 594 Pfam PF05124 S-layer like family, C-terminal region 429 563 1.0E-8 T 23-10-2018 IPR022651 S-layer protein, C-terminal A0127_00945 e5273348786c1e6a0ae9e15bef946086 433 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 209 415 1.2E-11 T 23-10-2018 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 A0127_00945 e5273348786c1e6a0ae9e15bef946086 433 SUPERFAMILY SSF52833 30 169 7.95E-11 T 23-10-2018 IPR036249 Thioredoxin-like superfamily A0127_00945 e5273348786c1e6a0ae9e15bef946086 433 Gene3D G3DSA:3.40.30.10 24 172 7.9E-11 T 23-10-2018 A0127_08630 3c21a74742417a0ec0e7f6de77a998cf 92 Gene3D G3DSA:1.10.287.1080 1 92 7.9E-26 T 23-10-2018 A0127_08630 3c21a74742417a0ec0e7f6de77a998cf 92 PIRSF PIRSF029904 1 92 4.7E-32 T 23-10-2018 IPR012359 NTP pyrophosphohydrolase MazG-related, YpjD A0127_08630 3c21a74742417a0ec0e7f6de77a998cf 92 SUPERFAMILY SSF101386 1 91 2.29E-21 T 23-10-2018 A0127_08630 3c21a74742417a0ec0e7f6de77a998cf 92 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 23 91 5.0E-14 T 23-10-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core A0127_04885 4fae455be2ad05c57c20cc7b28a0e944 175 TIGRFAM TIGR00708 cobA: cob(I)yrinic acid a,c-diamide adenosyltransferase 3 175 1.4E-71 T 23-10-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17 A0127_04885 4fae455be2ad05c57c20cc7b28a0e944 175 SUPERFAMILY SSF52540 4 175 3.38E-57 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_04885 4fae455be2ad05c57c20cc7b28a0e944 175 Pfam PF02572 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP 8 175 8.6E-62 T 23-10-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17 A0127_04885 4fae455be2ad05c57c20cc7b28a0e944 175 PIRSF PIRSF015617 1 175 6.3E-61 T 23-10-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17 A0127_04885 4fae455be2ad05c57c20cc7b28a0e944 175 Gene3D G3DSA:3.40.50.300 1 175 8.1E-66 T 23-10-2018 A0127_08895 9573f271b8e46896fe17efe1da21c803 83 Gene3D G3DSA:1.20.1280.290 1 83 2.7E-9 T 23-10-2018 A0127_06375 350fafd3c5287ecfdbcad948d20b780e 361 Pfam PF13394 4Fe-4S single cluster domain 31 122 6.3E-6 T 23-10-2018 A0127_06375 350fafd3c5287ecfdbcad948d20b780e 361 SUPERFAMILY SSF102114 27 207 5.23E-23 T 23-10-2018 A0127_06375 350fafd3c5287ecfdbcad948d20b780e 361 Pfam PF04055 Radical SAM superfamily 33 186 7.2E-12 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A0127_06375 350fafd3c5287ecfdbcad948d20b780e 361 Gene3D G3DSA:3.20.20.70 24 286 2.6E-16 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A0127_04940 0c5e1b4cdb961676ba9e65e37b02c37c 255 ProDom PD359573 MEMBRANE TRANSMEMBRANE AF2132 PROTEIN 4 252 9.0E-76 T 23-10-2018 A0127_08020 0e00ffb1cb300cebd2a163bd46fd98da 402 SUPERFAMILY SSF53743 1 281 6.8E-43 T 23-10-2018 IPR009015 L-fucose isomerase, N-terminal/central domain superfamily GO:0005737|GO:0005996|GO:0016861 A0127_06370 04912818b362f667723945fa8ff4008f 120 Pfam PF01900 Rpp14/Pop5 family 17 113 8.3E-22 T 23-10-2018 IPR002759 Ribonuclease P/MRP protein subunit GO:0004540|GO:0008033 Reactome: R-HSA-6784531 A0127_06370 04912818b362f667723945fa8ff4008f 120 Hamap MF_00755 Ribonuclease P protein component 2 [rnp2]. 5 116 26.727 T 23-10-2018 IPR002759 Ribonuclease P/MRP protein subunit GO:0004540|GO:0008033 Reactome: R-HSA-6784531 A0127_06370 04912818b362f667723945fa8ff4008f 120 PIRSF PIRSF004952 4 120 1.2E-46 T 23-10-2018 IPR016434 Ribonuclease P, protein component 2 GO:0001682|GO:0004526 A0127_06370 04912818b362f667723945fa8ff4008f 120 SUPERFAMILY SSF160350 4 116 9.42E-35 T 23-10-2018 IPR038085 Rnp2-like domain superfamily Reactome: R-HSA-6784531 A0127_06370 04912818b362f667723945fa8ff4008f 120 Gene3D G3DSA:3.30.70.3250 1 120 8.8E-50 T 23-10-2018 IPR038085 Rnp2-like domain superfamily Reactome: R-HSA-6784531 A0127_04680 c858a3a801db05956e57fd267177c350 277 Gene3D G3DSA:1.10.357.140 11 157 2.1E-18 T 23-10-2018 A0127_04680 c858a3a801db05956e57fd267177c350 277 Hamap MF_01286 Digeranylgeranylglyceryl phosphate synthase. 3 275 23.162 T 23-10-2018 IPR023547 Digeranylgeranylglyceryl phosphate synthase GO:0000287|GO:0005886|GO:0008654|GO:0047295 KEGG: 00564+2.5.1.42|MetaCyc: PWY-6349 A0127_04680 c858a3a801db05956e57fd267177c350 277 Pfam PF01040 UbiA prenyltransferase family 23 256 2.0E-46 T 23-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 A0127_03655 d0df37434271396449b75316d031206e 157 Pfam PF01917 Archaebacterial flagellin 5 155 4.8E-26 T 23-10-2018 IPR002774 Flagellin, archaea GO:0005198|GO:0006928 A0127_03655 d0df37434271396449b75316d031206e 157 SUPERFAMILY SSF49373 52 130 3.66E-5 T 23-10-2018 IPR008964 Invasin/intimin cell-adhesion fragments A0127_06410 fb3020c2129137b76c0de55e39bb0ec5 597 Gene3D G3DSA:3.20.110.20 46 297 1.1E-9 T 23-10-2018 A0127_06410 fb3020c2129137b76c0de55e39bb0ec5 597 Pfam PF03065 Glycosyl hydrolase family 57 95 324 1.1E-7 T 23-10-2018 IPR004300 Glycoside hydrolase family 57, N-terminal domain GO:0003824|GO:0005975 A0127_06410 fb3020c2129137b76c0de55e39bb0ec5 597 SUPERFAMILY SSF88713 6 228 8.15E-19 T 23-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 A0127_08855 8daceb191019c262549610762464c683 220 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 96 107 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A0127_08855 8daceb191019c262549610762464c683 220 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 61 72 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A0127_08855 8daceb191019c262549610762464c683 220 Gene3D G3DSA:3.30.70.3270 39 175 3.2E-23 T 23-10-2018 A0127_08855 8daceb191019c262549610762464c683 220 SUPERFAMILY SSF54862 40 137 1.47E-21 T 23-10-2018 A0127_08855 8daceb191019c262549610762464c683 220 Pfam PF12838 4Fe-4S dicluster domain 60 110 1.7E-11 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A0127_05140 caf370563cd2afddc90a4b1df6e01c02 364 Gene3D G3DSA:1.25.40.10 8 364 2.9E-72 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A0127_05140 caf370563cd2afddc90a4b1df6e01c02 364 SUPERFAMILY SSF48452 23 340 5.27E-12 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A0127_03350 6c1dd47be66c0dd8a12870f35ca2e144 334 SUPERFAMILY SSF52768 2 333 2.3E-89 T 23-10-2018 IPR023696 Ureohydrolase domain superfamily A0127_03350 6c1dd47be66c0dd8a12870f35ca2e144 334 Pfam PF00850 Histone deacetylase domain 20 288 2.3E-71 T 23-10-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 A0127_03350 6c1dd47be66c0dd8a12870f35ca2e144 334 PRINTS PR01270 Histone deacetylase superfamily signature 123 146 5.1E-11 T 23-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 A0127_03350 6c1dd47be66c0dd8a12870f35ca2e144 334 PRINTS PR01270 Histone deacetylase superfamily signature 155 170 5.1E-11 T 23-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 A0127_03350 6c1dd47be66c0dd8a12870f35ca2e144 334 PRINTS PR01270 Histone deacetylase superfamily signature 239 249 5.1E-11 T 23-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 A0127_03350 6c1dd47be66c0dd8a12870f35ca2e144 334 Gene3D G3DSA:3.40.800.20 6 327 3.2E-85 T 23-10-2018 IPR037138 Histone deacetylase domain superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 A0127_00680 6eafbd778a7ab0f2cef41566bfa12984 426 Pfam PF03600 Citrate transporter 18 366 1.7E-54 T 23-10-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 A0127_00680 6eafbd778a7ab0f2cef41566bfa12984 426 PRINTS PR00758 Arsenical pump membrane protein signature 221 246 4.3E-18 T 23-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 A0127_00680 6eafbd778a7ab0f2cef41566bfa12984 426 PRINTS PR00758 Arsenical pump membrane protein signature 101 125 4.3E-18 T 23-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 A0127_00680 6eafbd778a7ab0f2cef41566bfa12984 426 PRINTS PR00758 Arsenical pump membrane protein signature 278 302 4.3E-18 T 23-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 A0127_00680 6eafbd778a7ab0f2cef41566bfa12984 426 PRINTS PR00758 Arsenical pump membrane protein signature 395 419 4.3E-18 T 23-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 A0127_00680 6eafbd778a7ab0f2cef41566bfa12984 426 PRINTS PR00758 Arsenical pump membrane protein signature 322 344 4.3E-18 T 23-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 A0127_00680 6eafbd778a7ab0f2cef41566bfa12984 426 PRINTS PR00758 Arsenical pump membrane protein signature 362 387 4.3E-18 T 23-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 A0127_06755 8da5eb72fda57f452e1e6084def67af9 67 Pfam PF06093 Spt4/RpoE2 zinc finger 4 67 1.9E-12 T 23-10-2018 IPR022800 Spt4/RpoE2 zinc finger Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-75955 A0127_06755 8da5eb72fda57f452e1e6084def67af9 67 Gene3D G3DSA:2.20.28.90 1 67 5.7E-28 T 23-10-2018 IPR038589 Archaeal transcription elongation factor Spt4 superfamily A0127_06755 8da5eb72fda57f452e1e6084def67af9 67 ProDom PD019197 RNA DNA-DIRECTED POLYMERASE SUBUNIT E'' POLYMERASE RPOE2 TRANSFERASE NUCLEOTIDYLTRANSFERASE E 19 66 7.0E-20 T 23-10-2018 IPR007178 Archaeal transcription elongation factor Spt4 GO:0006355 A0127_06755 8da5eb72fda57f452e1e6084def67af9 67 SMART SM01389 4 67 1.4E-23 T 23-10-2018 IPR022800 Spt4/RpoE2 zinc finger Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-75955 A0127_06755 8da5eb72fda57f452e1e6084def67af9 67 SUPERFAMILY SSF63393 3 67 2.25E-17 T 23-10-2018 IPR029040 RNA polymerase subunit RPABC4/transcription elongation factor Spt4 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-75955 A0127_06755 8da5eb72fda57f452e1e6084def67af9 67 Hamap MF_00949 Transcription elongation factor Spt4 [spt4]. 6 67 25.396 T 23-10-2018 IPR007178 Archaeal transcription elongation factor Spt4 GO:0006355 A0127_06280 1fb13e9cc988047f91a74a7b992df945 396 SUPERFAMILY SSF116734 5 180 5.72E-44 T 23-10-2018 A0127_06280 1fb13e9cc988047f91a74a7b992df945 396 SUPERFAMILY SSF116734 186 390 1.8E-49 T 23-10-2018 A0127_06280 1fb13e9cc988047f91a74a7b992df945 396 Gene3D G3DSA:1.10.287.1120 134 384 3.5E-82 T 23-10-2018 A0127_06280 1fb13e9cc988047f91a74a7b992df945 396 Pfam PF01420 Type I restriction modification DNA specificity domain 14 157 7.6E-23 T 23-10-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 A0127_06280 1fb13e9cc988047f91a74a7b992df945 396 Pfam PF01420 Type I restriction modification DNA specificity domain 194 373 1.1E-31 T 23-10-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 A0127_06280 1fb13e9cc988047f91a74a7b992df945 396 Gene3D G3DSA:3.90.220.20 62 388 3.5E-82 T 23-10-2018 A0127_06280 1fb13e9cc988047f91a74a7b992df945 396 Gene3D G3DSA:3.90.220.20 198 341 3.5E-82 T 23-10-2018 A0127_03045 b4b2e8b06cd545873012808348c4433e 279 SUPERFAMILY SSF102114 14 203 1.96E-14 T 23-10-2018 A0127_03045 b4b2e8b06cd545873012808348c4433e 279 Pfam PF04055 Radical SAM superfamily 23 187 1.0E-15 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A0127_03045 b4b2e8b06cd545873012808348c4433e 279 Gene3D G3DSA:3.80.30.30 51 255 1.5E-13 T 23-10-2018 A0127_03045 b4b2e8b06cd545873012808348c4433e 279 SMART SM00729 18 228 2.7E-12 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A0127_03170 8af7dbf2449f56f58684247de930a4c4 457 PIRSF PIRSF005353 1 454 2.2E-159 T 23-10-2018 IPR026033 Purine permease PbuG-like A0127_03170 8af7dbf2449f56f58684247de930a4c4 457 Pfam PF00860 Permease family 20 412 1.6E-37 T 23-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 A0127_03980 d23a131977bd09f81d230075590d4210 200 Gene3D G3DSA:1.10.10.10 1 80 1.6E-24 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A0127_03980 d23a131977bd09f81d230075590d4210 200 Gene3D G3DSA:3.30.1360.30 81 191 4.6E-45 T 23-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 A0127_03980 d23a131977bd09f81d230075590d4210 200 Pfam PF14544 Domain of unknown function (DUF4443) 80 191 9.5E-68 T 23-10-2018 IPR029349 Domain of unknown function DUF4443 A0127_03980 d23a131977bd09f81d230075590d4210 200 SUPERFAMILY SSF46785 17 76 1.73E-10 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A0127_03980 d23a131977bd09f81d230075590d4210 200 SUPERFAMILY SSF55261 84 198 2.03E-39 T 23-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 A0127_07510 9f510742c238431121f053e71508062b 98 Pfam PF01253 Translation initiation factor SUI1 20 90 3.0E-20 T 23-10-2018 IPR001950 SUI1 domain GO:0003743|GO:0006413 A0127_07510 9f510742c238431121f053e71508062b 98 Hamap MF_00604 Protein translation factor SUI1 homolog. 2 93 26.927 T 23-10-2018 IPR022851 Translation factor SUI1 homolog, archaea A0127_07510 9f510742c238431121f053e71508062b 98 TIGRFAM TIGR01158 SUI1_rel: putative translation initiation factor SUI1 4 96 3.1E-36 T 23-10-2018 IPR005872 Archaeal/bacterial translation initiation factor SUI1 GO:0003743 A0127_07510 9f510742c238431121f053e71508062b 98 SUPERFAMILY SSF55159 5 91 1.57E-23 T 23-10-2018 IPR036877 SUI1 domain superfamily GO:0003743|GO:0006413 A0127_07510 9f510742c238431121f053e71508062b 98 Gene3D G3DSA:3.30.780.10 20 98 3.4E-29 T 23-10-2018 A0127_07510 9f510742c238431121f053e71508062b 98 PIRSF PIRSF037511 5 97 4.3E-26 T 23-10-2018 IPR005872 Archaeal/bacterial translation initiation factor SUI1 GO:0003743 A0127_00750 d6a4a28668e3c21f25a4156facc65990 279 SUPERFAMILY SSF53335 72 269 1.04E-48 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A0127_00750 d6a4a28668e3c21f25a4156facc65990 279 SMART SM00138 10 271 1.4E-81 T 23-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 A0127_00750 d6a4a28668e3c21f25a4156facc65990 279 Pfam PF01739 CheR methyltransferase, SAM binding domain 72 261 5.2E-57 T 23-10-2018 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal A0127_00750 d6a4a28668e3c21f25a4156facc65990 279 Gene3D G3DSA:3.40.50.150 71 273 1.1E-64 T 23-10-2018 A0127_00750 d6a4a28668e3c21f25a4156facc65990 279 PRINTS PR00996 Glutamate methyltransferase family signature 107 127 3.6E-36 T 23-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 A0127_00750 d6a4a28668e3c21f25a4156facc65990 279 PRINTS PR00996 Glutamate methyltransferase family signature 210 224 3.6E-36 T 23-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 A0127_00750 d6a4a28668e3c21f25a4156facc65990 279 PRINTS PR00996 Glutamate methyltransferase family signature 229 252 3.6E-36 T 23-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 A0127_00750 d6a4a28668e3c21f25a4156facc65990 279 PRINTS PR00996 Glutamate methyltransferase family signature 143 159 3.6E-36 T 23-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 A0127_00750 d6a4a28668e3c21f25a4156facc65990 279 PRINTS PR00996 Glutamate methyltransferase family signature 65 77 3.6E-36 T 23-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 A0127_00750 d6a4a28668e3c21f25a4156facc65990 279 PRINTS PR00996 Glutamate methyltransferase family signature 28 41 3.6E-36 T 23-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 A0127_00750 d6a4a28668e3c21f25a4156facc65990 279 Pfam PF03705 CheR methyltransferase, all-alpha domain 9 59 4.1E-10 T 23-10-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal A0127_00750 d6a4a28668e3c21f25a4156facc65990 279 SUPERFAMILY SSF47757 3 68 7.85E-13 T 23-10-2018 A0127_02475 6cc0a4bddf18d9d593e03aca34e430df 274 SUPERFAMILY SSF48317 56 226 4.25E-6 T 23-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily A0127_02475 6cc0a4bddf18d9d593e03aca34e430df 274 Pfam PF14378 PAP2 superfamily 66 217 1.9E-9 T 23-10-2018 IPR026841 Inositolphosphotransferase Aur1/Ipt1 A0127_02475 6cc0a4bddf18d9d593e03aca34e430df 274 Gene3D G3DSA:1.20.144.10 139 239 1.7E-5 T 23-10-2018 A0127_00475 f01d6da6ecf5fb1d41e9371f548ef5ce 244 SUPERFAMILY SSF52540 1 116 9.57E-12 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_00475 f01d6da6ecf5fb1d41e9371f548ef5ce 244 Pfam PF04060 Putative Fe-S cluster 160 191 4.3E-8 T 23-10-2018 IPR007202 4Fe-4S domain GO:0051536 A0127_00475 f01d6da6ecf5fb1d41e9371f548ef5ce 244 Gene3D G3DSA:3.40.50.300 1 157 6.9E-29 T 23-10-2018 A0127_00475 f01d6da6ecf5fb1d41e9371f548ef5ce 244 TIGRFAM TIGR00176 mobB: molybdopterin-guanine dinucleotide biosynthesis protein B 5 154 2.1E-23 T 23-10-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 A0127_00475 f01d6da6ecf5fb1d41e9371f548ef5ce 244 Gene3D G3DSA:3.20.20.20 158 222 1.3E-5 T 23-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 A0127_00475 f01d6da6ecf5fb1d41e9371f548ef5ce 244 Pfam PF03205 Molybdopterin guanine dinucleotide synthesis protein B 4 114 8.4E-18 T 23-10-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 A0127_03730 2abbe2cb212111d5bc9e92b000624af3 500 SUPERFAMILY SSF54826 342 400 1.06E-5 T 23-10-2018 A0127_03730 2abbe2cb212111d5bc9e92b000624af3 500 Gene3D G3DSA:1.10.10.10 437 498 2.4E-6 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A0127_09700 655dbed31ee7f13e7cad916ffc4e93b8 273 Pfam PF02361 Cobalt transport protein 31 236 2.1E-34 T 23-10-2018 IPR003339 ABC/ECF transporter, transmembrane component A0127_09700 655dbed31ee7f13e7cad916ffc4e93b8 273 TIGRFAM TIGR02454 ECF_T_CbiQ: cobalt ECF transporter T component CbiQ 35 232 1.0E-46 T 23-10-2018 IPR012809 Cobalt ECF transporter T component CbiQ GO:0005887|GO:0006824|GO:0043190 A0127_05325 a0eef97aa0dc0c8d3dcc8b44ba6cd2f1 119 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 6 115 2.2E-25 T 23-10-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like A0127_09340 7563eb0cdc2c5771780b75893a4f3d13 162 Gene3D G3DSA:3.40.50.720 1 161 7.5E-27 T 23-10-2018 A0127_09340 7563eb0cdc2c5771780b75893a4f3d13 162 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 131 1.1E-7 T 23-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 A0127_09340 7563eb0cdc2c5771780b75893a4f3d13 162 SUPERFAMILY SSF51735 1 153 4.48E-23 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A0127_09165 ecc30595d15b48fd244ea2465cbacc67 288 Gene3D G3DSA:3.40.50.10890 128 170 1.0E-23 T 23-10-2018 A0127_09165 ecc30595d15b48fd244ea2465cbacc67 288 SUPERFAMILY SSF56281 14 276 9.88E-42 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A0127_09165 ecc30595d15b48fd244ea2465cbacc67 288 Gene3D G3DSA:3.60.15.10 50 127 1.0E-23 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A0127_06830 9624ff0caddc9f9c877ffa4408380e44 261 PIRSF PIRSF004853 1 254 3.2E-116 T 23-10-2018 IPR002855 Phosphopantoate/pantothenate synthetase A0127_06830 9624ff0caddc9f9c877ffa4408380e44 261 Pfam PF02006 Phosphopantothenate/pantothenate synthetase 67 241 4.3E-76 T 23-10-2018 IPR002855 Phosphopantoate/pantothenate synthetase A0127_06830 9624ff0caddc9f9c877ffa4408380e44 261 Gene3D G3DSA:3.40.50.12640 1 261 1.3E-123 T 23-10-2018 IPR038138 Phosphopantoate/pantothenate synthetase superfamily A0127_06830 9624ff0caddc9f9c877ffa4408380e44 261 ProDom PD016827 ARCHAEA ST0532 APE1937 VNG0250C MM2281 PAE3406 AF0927 UNCHARACTERIZED C3_0043 MJ0209 67 252 2.0E-97 T 23-10-2018 IPR002855 Phosphopantoate/pantothenate synthetase A0127_00430 e307fd045c42d461c1ecba5e61b9dade 396 SUPERFAMILY SSF161093 221 394 4.84E-29 T 23-10-2018 IPR036739 SLC41 divalent cation transporters, integral membrane domain superfamily GO:0006812|GO:0008324 A0127_00430 e307fd045c42d461c1ecba5e61b9dade 396 Pfam PF01769 Divalent cation transporter 264 387 1.9E-15 T 23-10-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 A0127_00430 e307fd045c42d461c1ecba5e61b9dade 396 Pfam PF01769 Divalent cation transporter 61 183 1.4E-18 T 23-10-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 A0127_00430 e307fd045c42d461c1ecba5e61b9dade 396 SUPERFAMILY SSF161093 17 189 1.57E-26 T 23-10-2018 IPR036739 SLC41 divalent cation transporters, integral membrane domain superfamily GO:0006812|GO:0008324 A0127_00430 e307fd045c42d461c1ecba5e61b9dade 396 Gene3D G3DSA:1.10.357.20 14 190 3.1E-9 T 23-10-2018 IPR038048 Magnesium transporter MgtE, transmembrane domain A0127_00430 e307fd045c42d461c1ecba5e61b9dade 396 Gene3D G3DSA:1.10.357.20 217 394 2.3E-18 T 23-10-2018 IPR038048 Magnesium transporter MgtE, transmembrane domain A0127_05925 9adb55bded9c89d10ed26a16862255df 354 Gene3D G3DSA:1.20.81.30 170 286 1.2E-11 T 23-10-2018 A0127_05925 9adb55bded9c89d10ed26a16862255df 354 Pfam PF00482 Type II secretion system (T2SS), protein F 185 310 4.2E-23 T 23-10-2018 IPR018076 Type II secretion system F domain A0127_04235 fa1b3c7d148775f446e5348184cb0a5d 471 Pfam PF10150 Ribonuclease E/G family 152 262 7.2E-11 T 23-10-2018 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 A0127_04235 fa1b3c7d148775f446e5348184cb0a5d 471 Gene3D G3DSA:2.40.380.10 374 471 3.2E-11 T 23-10-2018 IPR035930 FomD-like superfamily A0127_04235 fa1b3c7d148775f446e5348184cb0a5d 471 Hamap MF_01910 RNA-binding protein AU-1 [aubA]. 7 471 35.473 T 23-10-2018 IPR016730 RNA-binding AU-1 GO:0003723 A0127_04235 fa1b3c7d148775f446e5348184cb0a5d 471 SUPERFAMILY SSF159234 319 471 4.18E-32 T 23-10-2018 IPR035930 FomD-like superfamily A0127_04235 fa1b3c7d148775f446e5348184cb0a5d 471 Pfam PF04167 Protein of unknown function (DUF402) 377 443 4.9E-15 T 23-10-2018 IPR007295 Domain of unknown function DUF402 A0127_04235 fa1b3c7d148775f446e5348184cb0a5d 471 PIRSF PIRSF018644 5 471 1.5E-201 T 23-10-2018 IPR016730 RNA-binding AU-1 GO:0003723 A0127_09450 0cdef3959ccaf17f62df8491dd2d98c9 197 SUPERFAMILY SSF46689 5 64 5.99E-20 T 23-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 A0127_09450 0cdef3959ccaf17f62df8491dd2d98c9 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 59 1.3E-20 T 23-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A0127_09450 0cdef3959ccaf17f62df8491dd2d98c9 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 34 57 1.7E-12 T 23-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A0127_09450 0cdef3959ccaf17f62df8491dd2d98c9 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 13 26 1.7E-12 T 23-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 A0127_09450 0cdef3959ccaf17f62df8491dd2d98c9 197 Gene3D G3DSA:1.10.357.10 2 193 1.3E-28 T 23-10-2018 A0127_09450 0cdef3959ccaf17f62df8491dd2d98c9 197 ProSitePatterns PS01081 TetR-type HTH domain signature. 25 56 - T 23-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site A0127_00005 5b5768eb38886601ebce16fdbed17dc4 183 SUPERFAMILY SSF47240 25 173 1.35E-14 T 23-10-2018 IPR009078 Ferritin-like superfamily A0127_00005 5b5768eb38886601ebce16fdbed17dc4 183 Gene3D G3DSA:1.20.1260.10 18 176 4.8E-15 T 23-10-2018 IPR012347 Ferritin-like A0127_03665 32ff7033503497081c00a83fdcf7a2fd 464 ProDom PD012942 FLAGELLUM FLAGELLA-RELATED E D ACCESSORY FLAGELLA ARCHAEAL FLAD SIMILAR D 347 448 5.0E-54 T 23-10-2018 IPR006752 Archaeal flagella protein FlaD/E domain GO:0097588 A0127_03665 32ff7033503497081c00a83fdcf7a2fd 464 Pfam PF04659 Archaeal flagella protein 343 436 8.0E-30 T 23-10-2018 IPR006752 Archaeal flagella protein FlaD/E domain GO:0097588 A0127_03665 32ff7033503497081c00a83fdcf7a2fd 464 PIRSF PIRSF017066 1 464 1.9E-147 T 23-10-2018 IPR016682 Flagella accessory protein D, predicted, archaeal A0127_07070 2e5f352daeffc51b89f357c7dc14d5cc 334 SUPERFAMILY SSF55347 156 314 4.51E-40 T 23-10-2018 A0127_07070 2e5f352daeffc51b89f357c7dc14d5cc 334 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 10 147 1.5E-6 T 23-10-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 A0127_07070 2e5f352daeffc51b89f357c7dc14d5cc 334 Gene3D G3DSA:3.30.360.10 167 310 8.7E-96 T 23-10-2018 A0127_07070 2e5f352daeffc51b89f357c7dc14d5cc 334 PIRSF PIRSF036497 1 334 2.6E-89 T 23-10-2018 IPR022697 Homoserine dehydrogenase lacking ACT domain GO:0004412 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 A0127_07070 2e5f352daeffc51b89f357c7dc14d5cc 334 SUPERFAMILY SSF51735 3 177 1.9E-30 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A0127_07070 2e5f352daeffc51b89f357c7dc14d5cc 334 Pfam PF00742 Homoserine dehydrogenase 156 327 3.3E-51 T 23-10-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 A0127_07070 2e5f352daeffc51b89f357c7dc14d5cc 334 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 201 223 - T 23-10-2018 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 A0127_07070 2e5f352daeffc51b89f357c7dc14d5cc 334 Gene3D G3DSA:3.40.50.720 6 327 8.7E-96 T 23-10-2018 A0127_05085 726347c4954312a79e373d225ad14a7f 272 Pfam PF01061 ABC-2 type transporter 39 227 2.3E-17 T 23-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 A0127_05085 726347c4954312a79e373d225ad14a7f 272 PRINTS PR00164 ABC-2 type transport system membrane protein signature 149 173 2.7E-11 T 23-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A0127_05085 726347c4954312a79e373d225ad14a7f 272 PRINTS PR00164 ABC-2 type transport system membrane protein signature 66 88 2.7E-11 T 23-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A0127_05085 726347c4954312a79e373d225ad14a7f 272 PRINTS PR00164 ABC-2 type transport system membrane protein signature 186 205 2.7E-11 T 23-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A0127_05085 726347c4954312a79e373d225ad14a7f 272 PRINTS PR00164 ABC-2 type transport system membrane protein signature 206 225 2.7E-11 T 23-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A0127_05085 726347c4954312a79e373d225ad14a7f 272 PIRSF PIRSF006648 7 262 3.2E-18 T 23-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A0127_01385 ff00e17f76fd6929be6924f8d760585f 253 SUPERFAMILY SSF56281 2 231 7.6E-33 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A0127_01385 ff00e17f76fd6929be6924f8d760585f 253 Gene3D G3DSA:3.60.15.10 1 253 1.7E-72 T 23-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like A0127_01385 ff00e17f76fd6929be6924f8d760585f 253 SMART SM00849 4 225 2.1E-8 T 23-10-2018 IPR001279 Metallo-beta-lactamase A0127_01385 ff00e17f76fd6929be6924f8d760585f 253 Pfam PF00753 Metallo-beta-lactamase superfamily 5 127 3.3E-17 T 23-10-2018 IPR001279 Metallo-beta-lactamase A0127_05050 1b42f89fced76ce8fcedccd0ae1e6431 299 SUPERFAMILY SSF52540 19 265 8.72E-59 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_05050 1b42f89fced76ce8fcedccd0ae1e6431 299 Hamap MF_02040 Iron-sulfur cluster carrier protein. 20 282 37.378 T 23-10-2018 IPR019591 Mrp/NBP35 ATP-binding protein A0127_05050 1b42f89fced76ce8fcedccd0ae1e6431 299 ProSitePatterns PS01215 Mrp family signature. 146 162 - T 23-10-2018 IPR000808 Mrp, conserved site GO:0005524 A0127_05050 1b42f89fced76ce8fcedccd0ae1e6431 299 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 30 281 2.3E-95 T 23-10-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 A0127_05050 1b42f89fced76ce8fcedccd0ae1e6431 299 Gene3D G3DSA:3.40.50.300 17 281 4.4E-82 T 23-10-2018 A0127_02030 8e9023d29b5bc1404f0850abce45cd43 419 SMART SM00471 53 191 2.1E-13 T 23-10-2018 IPR003607 HD/PDEase domain A0127_02030 8e9023d29b5bc1404f0850abce45cd43 419 Gene3D G3DSA:1.10.3210.10 8 330 3.9E-84 T 23-10-2018 A0127_02030 8e9023d29b5bc1404f0850abce45cd43 419 SUPERFAMILY SSF109604 7 414 3.14E-93 T 23-10-2018 A0127_02030 8e9023d29b5bc1404f0850abce45cd43 419 Pfam PF01966 HD domain 57 126 6.3E-14 T 23-10-2018 IPR006674 HD domain A0127_08040 6c0c85639b0e13dec2b365686d7f59fa 61 ProSitePatterns PS01067 Protein secE/sec61-gamma signature. 11 39 - T 23-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A0127_08040 6c0c85639b0e13dec2b365686d7f59fa 61 Hamap MF_00422 Protein translocase subunit SecE [secE]. 6 61 12.091 T 23-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A0127_08040 6c0c85639b0e13dec2b365686d7f59fa 61 TIGRFAM TIGR00327 secE_euk_arch: protein translocase SEC61 complex gamma subunit, archaeal and eukaryotic 5 60 2.6E-18 T 23-10-2018 IPR008158 Protein translocase SEC61 complex, gamma subunit GO:0015031|GO:0015450|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A0127_08040 6c0c85639b0e13dec2b365686d7f59fa 61 SUPERFAMILY SSF103456 4 58 6.8E-20 T 23-10-2018 IPR023391 Protein translocase SecE domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A0127_08040 6c0c85639b0e13dec2b365686d7f59fa 61 Gene3D G3DSA:1.20.5.820 1 61 1.3E-24 T 23-10-2018 IPR023391 Protein translocase SecE domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 A0127_01850 9d007c64a2f3b0989360d2720bf66ec0 353 SMART SM00382 28 211 2.8E-16 T 23-10-2018 IPR003593 AAA+ ATPase domain A0127_01850 9d007c64a2f3b0989360d2720bf66ec0 353 Gene3D G3DSA:3.40.50.300 1 237 4.0E-79 T 23-10-2018 A0127_01850 9d007c64a2f3b0989360d2720bf66ec0 353 Pfam PF08402 TOBE domain 275 349 1.4E-7 T 23-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 A0127_01850 9d007c64a2f3b0989360d2720bf66ec0 353 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 23-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 A0127_01850 9d007c64a2f3b0989360d2720bf66ec0 353 SUPERFAMILY SSF52540 4 244 7.45E-90 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_01850 9d007c64a2f3b0989360d2720bf66ec0 353 SUPERFAMILY SSF50331 237 350 4.76E-14 T 23-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal A0127_01850 9d007c64a2f3b0989360d2720bf66ec0 353 Pfam PF00005 ABC transporter 20 161 7.7E-35 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A0127_01850 9d007c64a2f3b0989360d2720bf66ec0 353 Gene3D G3DSA:2.40.50.100 238 346 4.4E-8 T 23-10-2018 A0127_01850 9d007c64a2f3b0989360d2720bf66ec0 353 Gene3D G3DSA:2.40.50.140 289 340 4.4E-8 T 23-10-2018 A0127_06960 35b2a72f3303f4ddd5c8f54737f96ea9 130 Gene3D G3DSA:3.10.129.10 1 129 8.5E-42 T 23-10-2018 A0127_06960 35b2a72f3303f4ddd5c8f54737f96ea9 130 Pfam PF03061 Thioesterase superfamily 40 112 3.7E-8 T 23-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 A0127_06960 35b2a72f3303f4ddd5c8f54737f96ea9 130 SUPERFAMILY SSF54637 20 119 1.18E-25 T 23-10-2018 IPR029069 HotDog domain superfamily A0127_06430 aefd43d119121dde123a3756b12d05ce 154 Gene3D G3DSA:3.40.50.2020 1 154 9.0E-53 T 23-10-2018 A0127_06430 aefd43d119121dde123a3756b12d05ce 154 SUPERFAMILY SSF53271 2 146 2.49E-34 T 23-10-2018 IPR029057 Phosphoribosyltransferase-like A0127_06430 aefd43d119121dde123a3756b12d05ce 154 Pfam PF00156 Phosphoribosyl transferase domain 14 150 8.4E-28 T 23-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 A0127_01150 d4ecc96b6a44edc1744f863846c759cb 206 SUPERFAMILY SSF144091 9 195 4.58E-39 T 23-10-2018 A0127_01150 d4ecc96b6a44edc1744f863846c759cb 206 Gene3D G3DSA:1.20.1540.10 4 199 1.3E-36 T 23-10-2018 IPR035952 Rhomboid-like superfamily A0127_01150 d4ecc96b6a44edc1744f863846c759cb 206 Pfam PF01694 Rhomboid family 56 190 5.1E-30 T 23-10-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 A0127_09330 2c35e0b9ea4d3007771240f4fd613b6e 446 SUPERFAMILY SSF55785 324 422 3.35E-10 T 23-10-2018 IPR035965 PAS domain superfamily A0127_09330 2c35e0b9ea4d3007771240f4fd613b6e 446 Pfam PF04282 Family of unknown function (DUF438) 15 80 1.6E-24 T 23-10-2018 IPR007380 Domain of unknown function DUF438 A0127_09330 2c35e0b9ea4d3007771240f4fd613b6e 446 Pfam PF01814 Hemerythrin HHE cation binding domain 94 233 6.5E-19 T 23-10-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 A0127_09330 2c35e0b9ea4d3007771240f4fd613b6e 446 Gene3D G3DSA:3.30.450.20 307 442 4.3E-46 T 23-10-2018 A0127_09330 2c35e0b9ea4d3007771240f4fd613b6e 446 Pfam PF13596 PAS domain 327 429 2.6E-21 T 23-10-2018 A0127_09330 2c35e0b9ea4d3007771240f4fd613b6e 446 Gene3D G3DSA:1.20.120.520 87 306 8.0E-59 T 23-10-2018 A0127_05345 1fdc0408af7bc481d75eea36cadee2d5 190 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 51 167 9.1E-19 T 23-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A0127_05345 1fdc0408af7bc481d75eea36cadee2d5 190 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 105 166 1.0E-26 T 23-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A0127_05345 1fdc0408af7bc481d75eea36cadee2d5 190 Gene3D G3DSA:3.30.460.80 22 149 3.1E-14 T 23-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A0127_05345 1fdc0408af7bc481d75eea36cadee2d5 190 SUPERFAMILY SSF143243 22 175 1.96E-27 T 23-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A0127_09530 45e7a1d17510297f55789687fdeaae9f 108 Gene3D G3DSA:3.30.420.130 2 108 1.4E-17 T 23-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily A0127_09530 45e7a1d17510297f55789687fdeaae9f 108 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 14 107 5.7E-14 T 23-10-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis A0127_09530 45e7a1d17510297f55789687fdeaae9f 108 SUPERFAMILY SSF53146 2 107 1.57E-21 T 23-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily A0127_05960 1afdc1256cf777972c8e2cf7ee3a61a4 317 SUPERFAMILY SSF52540 15 287 5.57E-47 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_05960 1afdc1256cf777972c8e2cf7ee3a61a4 317 PIRSF PIRSF002849 1 316 6.7E-139 T 23-10-2018 A0127_05960 1afdc1256cf777972c8e2cf7ee3a61a4 317 Gene3D G3DSA:1.10.8.300 202 311 4.4E-38 T 23-10-2018 A0127_05960 1afdc1256cf777972c8e2cf7ee3a61a4 317 Gene3D G3DSA:3.40.50.300 21 187 3.0E-47 T 23-10-2018 A0127_05960 1afdc1256cf777972c8e2cf7ee3a61a4 317 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 40 170 2.0E-67 T 23-10-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 A0127_01550 38941b0dac5b101d3a466fbb5464cdb0 574 PIRSF PIRSF029254 1 574 7.1E-193 T 23-10-2018 IPR012401 DNA-binding protein MutS2, archaea A0127_01550 38941b0dac5b101d3a466fbb5464cdb0 574 SUPERFAMILY SSF52540 382 555 1.41E-17 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_01550 38941b0dac5b101d3a466fbb5464cdb0 574 SMART SM00534 386 574 1.9E-28 T 23-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 A0127_01550 38941b0dac5b101d3a466fbb5464cdb0 574 Gene3D G3DSA:3.40.50.300 338 556 4.3E-21 T 23-10-2018 A0127_01550 38941b0dac5b101d3a466fbb5464cdb0 574 Hamap MF_00971 DNA-binding protein MutS2 [mutS2]. 3 573 25.404 T 23-10-2018 IPR012401 DNA-binding protein MutS2, archaea A0127_01550 38941b0dac5b101d3a466fbb5464cdb0 574 Pfam PF00488 MutS domain V 389 434 7.9E-8 T 23-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 A0127_07585 b187ff583eefa5af71c95c9f41ecb985 148 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 1 148 14.983 T 23-10-2018 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 A0127_07585 b187ff583eefa5af71c95c9f41ecb985 148 Gene3D G3DSA:3.100.10.10 63 148 3.0E-20 T 23-10-2018 A0127_07585 b187ff583eefa5af71c95c9f41ecb985 148 SUPERFAMILY SSF52080 5 147 2.88E-33 T 23-10-2018 IPR036227 Ribosomal L18e/L15P superfamily A0127_07585 b187ff583eefa5af71c95c9f41ecb985 148 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 29 146 1.8E-19 T 23-10-2018 IPR021131 Ribosomal protein L18e/L15P A0127_07585 b187ff583eefa5af71c95c9f41ecb985 148 ProSitePatterns PS00475 Ribosomal protein L15 signature. 112 142 - T 23-10-2018 IPR001196 Ribosomal protein L15, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_07585 b187ff583eefa5af71c95c9f41ecb985 148 Gene3D G3DSA:4.10.990.10 4 53 3.5E-10 T 23-10-2018 IPR027386 50S ribosomal protein L15, N-terminal A0127_09410 f2f8568d78e7aa1506bc651e6271276a 531 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 78 103 1.2E-7 T 23-10-2018 A0127_09410 f2f8568d78e7aa1506bc651e6271276a 531 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 228 249 1.2E-7 T 23-10-2018 A0127_09410 f2f8568d78e7aa1506bc651e6271276a 531 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 322 334 1.2E-7 T 23-10-2018 A0127_09410 f2f8568d78e7aa1506bc651e6271276a 531 Pfam PF00361 Proton-conducting membrane transporter 130 431 2.1E-60 T 23-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A0127_02975 2aed9c249d371cf58e01c2e36ecf3595 251 Gene3D G3DSA:3.40.50.300 1 251 8.1E-71 T 23-10-2018 A0127_08255 985839634fece29ca168d224e02a18de 419 SMART SM00283 143 418 4.7E-55 T 23-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 A0127_08255 985839634fece29ca168d224e02a18de 419 Gene3D G3DSA:1.10.287.950 124 418 7.2E-62 T 23-10-2018 A0127_08255 985839634fece29ca168d224e02a18de 419 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 197 358 6.2E-39 T 23-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 A0127_08255 985839634fece29ca168d224e02a18de 419 SUPERFAMILY SSF58104 91 418 5.23E-61 T 23-10-2018 A0127_00270 8e0d0f77a493f2d4d65c7b9334f72b82 63 ProDom PD005132 RIBOSOMAL RRNA-BINDING METAL-BINDING RNA-BINDING ZINC RIBONUCLEOPROTEIN ZINC-FINGER L37 60S L37E 9 51 8.0E-18 T 23-10-2018 IPR001569 Ribosomal protein L37e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_00270 8e0d0f77a493f2d4d65c7b9334f72b82 63 ProSitePatterns PS01077 Ribosomal protein L37e signature. 4 24 - T 23-10-2018 IPR018267 Ribosomal protein L37e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_00270 8e0d0f77a493f2d4d65c7b9334f72b82 63 Pfam PF01907 Ribosomal protein L37e 3 55 1.5E-21 T 23-10-2018 IPR001569 Ribosomal protein L37e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_00270 8e0d0f77a493f2d4d65c7b9334f72b82 63 Gene3D G3DSA:2.20.25.30 1 57 1.3E-20 T 23-10-2018 IPR011331 Ribosomal protein L37ae/L37e GO:0003735|GO:0005622|GO:0005840|GO:0006412 A0127_00270 8e0d0f77a493f2d4d65c7b9334f72b82 63 Hamap MF_00547 50S ribosomal protein L37e [rpl37e]. 2 55 20.905 T 23-10-2018 IPR001569 Ribosomal protein L37e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_00270 8e0d0f77a493f2d4d65c7b9334f72b82 63 SUPERFAMILY SSF57829 1 56 2.2E-19 T 23-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 A0127_05370 b0c243507bd35c4c588d863d39bb75ed 159 Pfam PF02915 Rubrerythrin 104 157 5.4E-8 T 23-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 A0127_05370 b0c243507bd35c4c588d863d39bb75ed 159 Pfam PF02915 Rubrerythrin 18 80 8.9E-9 T 23-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 A0127_05370 b0c243507bd35c4c588d863d39bb75ed 159 SUPERFAMILY SSF47240 14 158 3.08E-26 T 23-10-2018 IPR009078 Ferritin-like superfamily A0127_05370 b0c243507bd35c4c588d863d39bb75ed 159 Gene3D G3DSA:1.20.1260.10 8 157 2.6E-31 T 23-10-2018 IPR012347 Ferritin-like A0127_08380 de398c872936ef6b974be1db4df3ea25 386 Gene3D G3DSA:1.20.1250.20 7 210 5.7E-26 T 23-10-2018 A0127_08380 de398c872936ef6b974be1db4df3ea25 386 Pfam PF07690 Major Facilitator Superfamily 16 340 2.3E-27 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A0127_08380 de398c872936ef6b974be1db4df3ea25 386 Gene3D G3DSA:1.20.1250.20 211 386 1.3E-17 T 23-10-2018 A0127_08380 de398c872936ef6b974be1db4df3ea25 386 SUPERFAMILY SSF103473 12 382 1.7E-50 T 23-10-2018 IPR036259 MFS transporter superfamily A0127_09435 e9b55e280c69e2883a80d184de9e38ef 86 Pfam PF01455 HupF/HypC family 1 67 5.0E-24 T 23-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC A0127_09435 e9b55e280c69e2883a80d184de9e38ef 86 SUPERFAMILY SSF159127 1 76 4.32E-22 T 23-10-2018 IPR037254 HupF/HypC superfamily A0127_09435 e9b55e280c69e2883a80d184de9e38ef 86 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 2 9 2.7E-8 T 23-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC A0127_09435 e9b55e280c69e2883a80d184de9e38ef 86 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 40 56 2.7E-8 T 23-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC A0127_09435 e9b55e280c69e2883a80d184de9e38ef 86 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 19 35 2.7E-8 T 23-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC A0127_09435 e9b55e280c69e2883a80d184de9e38ef 86 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 58 70 2.7E-8 T 23-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC A0127_09435 e9b55e280c69e2883a80d184de9e38ef 86 TIGRFAM TIGR00074 hypC_hupF: hydrogenase assembly chaperone HypC/HupF 1 76 3.5E-23 T 23-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC A0127_09435 e9b55e280c69e2883a80d184de9e38ef 86 Gene3D G3DSA:2.40.50.970 1 75 4.6E-27 T 23-10-2018 IPR037254 HupF/HypC superfamily A0127_03075 6afea24ae1e27721305c3e18dcbab68e 472 SUPERFAMILY SSF50998 22 317 7.46E-11 T 23-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily A0127_05550 fda15e9b96df950dbdff21b66b5bde67 341 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 11 321 1.8E-58 T 23-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD A0127_05550 fda15e9b96df950dbdff21b66b5bde67 341 TIGRFAM TIGR00374 TIGR00374: TIGR00374 family protein 12 337 5.5E-61 T 23-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD A0127_04035 56ec3d6938f66e6d93df1213c001fe02 390 Gene3D G3DSA:1.20.1250.20 186 382 9.7E-8 T 23-10-2018 A0127_04035 56ec3d6938f66e6d93df1213c001fe02 390 Gene3D G3DSA:1.20.1250.20 3 185 9.4E-10 T 23-10-2018 A0127_04035 56ec3d6938f66e6d93df1213c001fe02 390 SUPERFAMILY SSF103473 20 379 3.27E-26 T 23-10-2018 IPR036259 MFS transporter superfamily A0127_04035 56ec3d6938f66e6d93df1213c001fe02 390 Pfam PF07690 Major Facilitator Superfamily 23 347 1.5E-15 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A0127_08155 5c96bc2508ae4f0bd6987a29e73ddd3d 248 Gene3D G3DSA:3.20.20.190 1 248 3.5E-102 T 23-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 A0127_08155 5c96bc2508ae4f0bd6987a29e73ddd3d 248 SUPERFAMILY SSF51695 6 214 3.35E-61 T 23-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 A0127_08155 5c96bc2508ae4f0bd6987a29e73ddd3d 248 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 12 212 3.3E-36 T 23-10-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 A0127_02270 04146d64e35e60d741ac945ebf1fdc07 250 Pfam PF07786 Protein of unknown function (DUF1624) 11 232 2.3E-61 T 23-10-2018 IPR012429 Domain of unknown function DUF1624 Reactome: R-HSA-2024096|Reactome: R-HSA-2206291|Reactome: R-HSA-6798695 A0127_08925 af6c017631f3b720fc25e36a73a0d06b 325 SUPERFAMILY SSF88723 105 245 8.44E-5 T 23-10-2018 IPR029060 PIN-like domain superfamily A0127_08060 5a1264cfaadf288923adfef2eb9327bd 340 SUPERFAMILY SSF160369 5 141 1.19E-25 T 23-10-2018 A0127_08060 5a1264cfaadf288923adfef2eb9327bd 340 Gene3D G3DSA:3.90.105.20 107 186 1.2E-74 T 23-10-2018 A0127_08060 5a1264cfaadf288923adfef2eb9327bd 340 Gene3D G3DSA:3.30.70.1730 15 210 1.2E-74 T 23-10-2018 A0127_08060 5a1264cfaadf288923adfef2eb9327bd 340 Pfam PF00466 Ribosomal protein L10 5 105 2.2E-21 T 23-10-2018 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 A0127_08060 5a1264cfaadf288923adfef2eb9327bd 340 Hamap MF_00280 50S ribosomal protein L10 [rpl10]. 1 283 36.384 T 23-10-2018 IPR022909 50S ribosomal protein L10, archaea A0127_00405 51673279b3aa1cf2acf1e4152bb56e04 393 SUPERFAMILY SSF48452 176 386 6.83E-7 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A0127_00405 51673279b3aa1cf2acf1e4152bb56e04 393 SUPERFAMILY SSF48452 13 165 2.09E-8 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A0127_03950 b05a4aadd82cda32375caf1891c6be6e 273 SUPERFAMILY SSF53613 1 250 2.03E-31 T 23-10-2018 IPR029056 Ribokinase-like A0127_03950 b05a4aadd82cda32375caf1891c6be6e 273 Pfam PF00294 pfkB family carbohydrate kinase 172 258 1.4E-5 T 23-10-2018 IPR011611 Carbohydrate kinase PfkB A0127_03950 b05a4aadd82cda32375caf1891c6be6e 273 Gene3D G3DSA:3.40.1190.20 1 273 1.7E-104 T 23-10-2018 IPR029056 Ribokinase-like A0127_02435 3039745bfe56bc5a49b4be13cf0f0806 146 Pfam PF05763 Protein of unknown function (DUF835) 26 143 4.5E-22 T 23-10-2018 IPR008553 Domain of unknown function DUF835 A0127_02010 8c63f769605413ae3de7cada59800e5c 203 Pfam PF01955 Adenosylcobinamide amidohydrolase 10 182 9.2E-46 T 23-10-2018 IPR002808 Adenosylcobinamide amidohydrolase, CbiZ A0127_02375 1f59dde127dbdd37c344490eb9c49a90 206 SUPERFAMILY SSF109604 14 205 5.71E-63 T 23-10-2018 A0127_02375 1f59dde127dbdd37c344490eb9c49a90 206 Pfam PF01966 HD domain 35 137 3.6E-19 T 23-10-2018 IPR006674 HD domain A0127_02375 1f59dde127dbdd37c344490eb9c49a90 206 TIGRFAM TIGR00277 HDIG: HDIG domain 34 95 3.1E-9 T 23-10-2018 IPR006675 HDIG domain A0127_02375 1f59dde127dbdd37c344490eb9c49a90 206 Gene3D G3DSA:1.10.3210.50 12 206 8.5E-66 T 23-10-2018 A0127_02375 1f59dde127dbdd37c344490eb9c49a90 206 SMART SM00471 30 147 3.5E-11 T 23-10-2018 IPR003607 HD/PDEase domain A0127_06730 ed4a1dc713573c9f230d17783227f40c 355 TIGRFAM TIGR02228 sigpep_I_arch: signal peptidase I 9 118 6.3E-16 T 23-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 A0127_06730 ed4a1dc713573c9f230d17783227f40c 355 SUPERFAMILY SSF51306 36 95 1.7E-8 T 23-10-2018 IPR036286 LexA/Signal peptidase-like superfamily A0127_06730 ed4a1dc713573c9f230d17783227f40c 355 Gene3D G3DSA:2.10.109.10 36 133 1.3E-6 T 23-10-2018 A0127_06730 ed4a1dc713573c9f230d17783227f40c 355 PRINTS PR00728 Eukaryotic signal peptidase (S26B) family signature 35 50 3.3E-5 T 23-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 A0127_06730 ed4a1dc713573c9f230d17783227f40c 355 PRINTS PR00728 Eukaryotic signal peptidase (S26B) family signature 86 97 3.3E-5 T 23-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 A0127_06730 ed4a1dc713573c9f230d17783227f40c 355 Pfam PF00717 Peptidase S24-like 36 89 3.5E-9 T 23-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C A0127_09290 1fc6187d4bb0688094113b0cce95df5e 186 SUPERFAMILY SSF53323 1 179 1.44E-39 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 A0127_09290 1fc6187d4bb0688094113b0cce95df5e 186 Gene3D G3DSA:3.40.920.10 1 185 7.3E-52 T 23-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 A0127_09290 1fc6187d4bb0688094113b0cce95df5e 186 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 11 176 1.1E-32 T 23-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 A0127_07820 63a703c852b0b6a92f346a9133672f55 291 Gene3D G3DSA:3.40.830.10 1 290 2.4E-66 T 23-10-2018 A0127_07820 63a703c852b0b6a92f346a9133672f55 291 SUPERFAMILY SSF53213 56 255 2.88E-7 T 23-10-2018 A0127_07820 63a703c852b0b6a92f346a9133672f55 291 TIGRFAM TIGR04336 AmmeMemoSam_B: AmmeMemoRadiSam system protein B 3 289 2.6E-88 T 23-10-2018 A0127_07820 63a703c852b0b6a92f346a9133672f55 291 Hamap MF_00055 MEMO1 family protein . 1 290 59.921 T 23-10-2018 IPR002737 MEMO1 family Reactome: R-HSA-6785631 A0127_07820 63a703c852b0b6a92f346a9133672f55 291 Pfam PF01875 Memo-like protein 5 288 2.7E-72 T 23-10-2018 IPR002737 MEMO1 family Reactome: R-HSA-6785631 A0127_08300 1ba14715d377a887c8f3d717357543a6 393 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 238 317 1.4E-25 T 23-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal A0127_08300 1ba14715d377a887c8f3d717357543a6 393 Pfam PF07282 Putative transposase DNA-binding domain 290 356 9.6E-26 T 23-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal A0127_08300 1ba14715d377a887c8f3d717357543a6 393 SUPERFAMILY SSF75712 273 336 1.83E-10 T 23-10-2018 A0127_08300 1ba14715d377a887c8f3d717357543a6 393 Pfam PF01385 Probable transposase 168 259 1.5E-8 T 23-10-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 A0127_00850 ca88a0c7da26d9f745bf9c2ea76250b4 65 Pfam PF11127 Protein of unknown function (DUF2892) 1 64 3.0E-20 T 23-10-2018 IPR021309 Protein of unknown function DUF2892 A0127_05220 87b53fda053a8878ac9b841248057de2 184 Pfam PF12679 ABC-2 family transporter protein 2 183 3.3E-12 T 23-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 A0127_03910 5c0b768765d47d52a7f2bd4415693860 143 Pfam PF04027 Domain of unknown function (DUF371) 6 137 1.8E-50 T 23-10-2018 IPR007171 Protein of unknown function DUF371 A0127_03910 5c0b768765d47d52a7f2bd4415693860 143 Gene3D G3DSA:2.60.120.630 1 142 3.7E-53 T 23-10-2018 IPR023131 Mth639-like domain superfamily A0127_02570 b0284a3e85070fd5b2485cc4d2c4442a 268 Pfam PF01145 SPFH domain / Band 7 family 26 196 1.3E-39 T 23-10-2018 IPR001107 Band 7 domain A0127_02570 b0284a3e85070fd5b2485cc4d2c4442a 268 SMART SM00244 22 179 3.2E-70 T 23-10-2018 IPR001107 Band 7 domain A0127_02570 b0284a3e85070fd5b2485cc4d2c4442a 268 SUPERFAMILY SSF117892 53 186 2.75E-47 T 23-10-2018 IPR036013 Band 7/SPFH domain superfamily A0127_02570 b0284a3e85070fd5b2485cc4d2c4442a 268 PRINTS PR00721 Stomatin signature 199 222 1.1E-73 T 23-10-2018 IPR001972 Stomatin family GO:0016020 A0127_02570 b0284a3e85070fd5b2485cc4d2c4442a 268 PRINTS PR00721 Stomatin signature 111 128 1.1E-73 T 23-10-2018 IPR001972 Stomatin family GO:0016020 A0127_02570 b0284a3e85070fd5b2485cc4d2c4442a 268 PRINTS PR00721 Stomatin signature 174 195 1.1E-73 T 23-10-2018 IPR001972 Stomatin family GO:0016020 A0127_02570 b0284a3e85070fd5b2485cc4d2c4442a 268 PRINTS PR00721 Stomatin signature 29 51 1.1E-73 T 23-10-2018 IPR001972 Stomatin family GO:0016020 A0127_02570 b0284a3e85070fd5b2485cc4d2c4442a 268 PRINTS PR00721 Stomatin signature 131 154 1.1E-73 T 23-10-2018 IPR001972 Stomatin family GO:0016020 A0127_02570 b0284a3e85070fd5b2485cc4d2c4442a 268 PRINTS PR00721 Stomatin signature 155 173 1.1E-73 T 23-10-2018 IPR001972 Stomatin family GO:0016020 A0127_02570 b0284a3e85070fd5b2485cc4d2c4442a 268 PRINTS PR00721 Stomatin signature 76 97 1.1E-73 T 23-10-2018 IPR001972 Stomatin family GO:0016020 A0127_02570 b0284a3e85070fd5b2485cc4d2c4442a 268 Gene3D G3DSA:3.30.479.30 50 181 2.1E-52 T 23-10-2018 A0127_01105 29ad9fe412edacbd093b61d92b2f2ab4 414 Pfam PF04409 Protein of unknown function (DUF530) 5 255 3.5E-25 T 23-10-2018 IPR007503 Protein of unknown function DUF530 A0127_00190 1ac898822979c5fb0e262ffee9709ea2 468 TIGRFAM TIGR04288 CGP_CTERM: CGP-CTERM domain 448 467 1.4E-8 T 23-10-2018 IPR027552 CGP-CTERM domain A0127_04980 0ca65b94eedab0375f3fa72836a0b692 512 SUPERFAMILY SSF48371 42 445 1.78E-39 T 23-10-2018 IPR016024 Armadillo-type fold A0127_04980 0ca65b94eedab0375f3fa72836a0b692 512 Gene3D G3DSA:1.25.10.10 287 466 7.0E-9 T 23-10-2018 IPR011989 Armadillo-like helical A0127_04980 0ca65b94eedab0375f3fa72836a0b692 512 Gene3D G3DSA:1.25.10.10 10 271 2.3E-22 T 23-10-2018 IPR011989 Armadillo-like helical A0127_09510 dcb5a4a3db75375e518780f650bc3f7e 157 TIGRFAM TIGR00072 hydrog_prot: hydrogenase maturation protease 15 154 4.5E-31 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 A0127_09510 dcb5a4a3db75375e518780f650bc3f7e 157 PRINTS PR00446 Hydrogen uptake protein signature 14 26 4.2E-7 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 A0127_09510 dcb5a4a3db75375e518780f650bc3f7e 157 PRINTS PR00446 Hydrogen uptake protein signature 68 78 4.2E-7 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 A0127_09510 dcb5a4a3db75375e518780f650bc3f7e 157 PRINTS PR00446 Hydrogen uptake protein signature 26 37 4.2E-7 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 A0127_09510 dcb5a4a3db75375e518780f650bc3f7e 157 Pfam PF01750 Hydrogenase maturation protease 31 151 4.0E-13 T 23-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 A0127_09510 dcb5a4a3db75375e518780f650bc3f7e 157 SUPERFAMILY SSF53163 12 156 1.09E-29 T 23-10-2018 IPR023430 Peptidase HybD-like domain superfamily A0127_09510 dcb5a4a3db75375e518780f650bc3f7e 157 Gene3D G3DSA:3.40.50.1450 10 156 1.7E-40 T 23-10-2018 IPR023430 Peptidase HybD-like domain superfamily A0127_08335 ef8769b2b9dff0f6b0145687ce36ae77 99 Pfam PF04242 Protein of unknown function (DUF424) 7 97 3.0E-33 T 23-10-2018 IPR007355 Protein of unknown function DUF424 A0127_08335 ef8769b2b9dff0f6b0145687ce36ae77 99 Gene3D G3DSA:3.30.1860.10 1 97 1.0E-35 T 23-10-2018 A0127_05480 35b8d2ddfd7deea30e673c9c1e4f0966 232 SUPERFAMILY SSF69572 2 230 1.12E-80 T 23-10-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 A0127_05480 35b8d2ddfd7deea30e673c9c1e4f0966 232 Pfam PF00899 ThiF family 10 231 8.9E-60 T 23-10-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 A0127_05480 35b8d2ddfd7deea30e673c9c1e4f0966 232 Gene3D G3DSA:3.40.50.720 2 232 7.8E-75 T 23-10-2018 A0127_05095 bf184426ec3de8c2fff2d6866ef538a9 197 PIRSF PIRSF004897 1 165 8.1E-44 T 23-10-2018 IPR014424 Uncharacterised conserved protein UCP004897, ACT- type A0127_07505 94a401453e31cdb4f92799e0a8affbc7 66 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 1 61 15.682 T 23-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_07505 94a401453e31cdb4f92799e0a8affbc7 66 Pfam PF00831 Ribosomal L29 protein 4 61 8.1E-18 T 23-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_07505 94a401453e31cdb4f92799e0a8affbc7 66 ProSitePatterns PS00579 Ribosomal protein L29 signature. 40 54 - T 23-10-2018 IPR018254 Ribosomal protein L29, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_07505 94a401453e31cdb4f92799e0a8affbc7 66 TIGRFAM TIGR00012 L29: ribosomal protein uL29 5 61 9.0E-21 T 23-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_07505 94a401453e31cdb4f92799e0a8affbc7 66 SUPERFAMILY SSF46561 1 61 2.62E-16 T 23-10-2018 IPR036049 Ribosomal protein L29/L35 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_07505 94a401453e31cdb4f92799e0a8affbc7 66 Gene3D G3DSA:1.10.287.310 1 66 1.7E-19 T 23-10-2018 A0127_00685 bd2bcb81386058279d69c024de5ea0dc 181 Gene3D G3DSA:3.40.50.620 42 181 1.6E-9 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A0127_00685 bd2bcb81386058279d69c024de5ea0dc 181 SUPERFAMILY SSF52402 64 180 1.59E-9 T 23-10-2018 A0127_04500 c082ca9ae57af16da65f9e72d6ab87d0 561 SUPERFAMILY SSF53187 9 415 1.82E-29 T 23-10-2018 A0127_04500 c082ca9ae57af16da65f9e72d6ab87d0 561 Gene3D G3DSA:3.40.630.10 28 401 1.8E-49 T 23-10-2018 A0127_04500 c082ca9ae57af16da65f9e72d6ab87d0 561 Pfam PF04389 Peptidase family M28 227 408 3.3E-16 T 23-10-2018 IPR007484 Peptidase M28 A0127_04500 c082ca9ae57af16da65f9e72d6ab87d0 561 Gene3D G3DSA:3.50.30.30 71 207 1.8E-49 T 23-10-2018 A0127_03675 d51a87bb8068144e5a1850b4b77b5fcf 260 Pfam PF01917 Archaebacterial flagellin 4 246 1.1E-42 T 23-10-2018 IPR002774 Flagellin, archaea GO:0005198|GO:0006928 A0127_03675 d51a87bb8068144e5a1850b4b77b5fcf 260 TIGRFAM TIGR02537 arch_flag_Nterm: archaeal flagellin N-terminal-like domain 2 25 5.0E-4 T 23-10-2018 IPR013373 Flagellin/pilin, N-terminal A0127_07080 41d42f87dbbb30e0cda2502012b670f1 397 Pfam PF03977 Na+-transporting oxaloacetate decarboxylase beta subunit 20 395 2.8E-157 T 23-10-2018 IPR005661 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit GO:0006814|GO:0016829 KEGG: 00620+4.1.1.3 A0127_07080 41d42f87dbbb30e0cda2502012b670f1 397 TIGRFAM TIGR01109 Na_pump_decarbB: sodium ion-translocating decarboxylase, beta subunit 19 391 8.8E-158 T 23-10-2018 IPR005661 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit GO:0006814|GO:0016829 KEGG: 00620+4.1.1.3 A0127_07080 41d42f87dbbb30e0cda2502012b670f1 397 PIRSF PIRSF015658 1 397 3.8E-167 T 23-10-2018 IPR005661 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit GO:0006814|GO:0016829 KEGG: 00620+4.1.1.3 A0127_01720 a161ff30b1682707f6dcb6525432a1e4 205 Pfam PF09186 Domain of unknown function (DUF1949) 139 194 3.0E-14 T 23-10-2018 IPR015269 Uncharacterised domain UPF0029, Impact, C-terminal A0127_01720 a161ff30b1682707f6dcb6525432a1e4 205 SUPERFAMILY SSF54980 136 198 7.19E-11 T 23-10-2018 IPR035647 EF-G domain III/V-like A0127_01720 a161ff30b1682707f6dcb6525432a1e4 205 ProSitePatterns PS00910 Uncharacterized protein family UPF0029 signature. 78 107 - T 23-10-2018 IPR020569 Uncharacterised protein family UPF0029, Impact, conserved site A0127_01720 a161ff30b1682707f6dcb6525432a1e4 205 Gene3D G3DSA:3.30.230.30 2 130 9.7E-45 T 23-10-2018 IPR036956 Impact, N-terminal domain superfamily A0127_01720 a161ff30b1682707f6dcb6525432a1e4 205 Pfam PF01205 Uncharacterized protein family UPF0029 17 123 2.6E-31 T 23-10-2018 IPR001498 Impact, N-terminal A0127_01720 a161ff30b1682707f6dcb6525432a1e4 205 SUPERFAMILY SSF54211 3 130 2.28E-40 T 23-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold A0127_08695 dc4a660369aa8b66dd4a441a93a891d5 183 Gene3D G3DSA:1.10.10.10 126 183 2.2E-5 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A0127_00900 8ae3f6dd808ed7cc754f98c839f39edb 566 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 129 135 - T 23-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 A0127_00900 8ae3f6dd808ed7cc754f98c839f39edb 566 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 165 189 9.1E-18 T 23-10-2018 A0127_00900 8ae3f6dd808ed7cc754f98c839f39edb 566 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 38 52 9.1E-18 T 23-10-2018 A0127_00900 8ae3f6dd808ed7cc754f98c839f39edb 566 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 14 30 9.1E-18 T 23-10-2018 A0127_00900 8ae3f6dd808ed7cc754f98c839f39edb 566 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 126 138 9.1E-18 T 23-10-2018 A0127_00900 8ae3f6dd808ed7cc754f98c839f39edb 566 Pfam PF02384 N-6 DNA Methylase 6 237 2.2E-17 T 23-10-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 A0127_00900 8ae3f6dd808ed7cc754f98c839f39edb 566 SUPERFAMILY SSF53335 8 275 1.38E-47 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A0127_00900 8ae3f6dd808ed7cc754f98c839f39edb 566 Gene3D G3DSA:3.40.50.150 16 248 2.1E-44 T 23-10-2018 A0127_05010 ed6644ce627c2461aaa3a6f18ddd5fa8 311 SUPERFAMILY SSF52518 16 308 8.84E-69 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold A0127_05010 ed6644ce627c2461aaa3a6f18ddd5fa8 311 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 92 218 4.8E-19 T 23-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 A0127_05010 ed6644ce627c2461aaa3a6f18ddd5fa8 311 Gene3D G3DSA:3.40.50.970 97 310 2.0E-68 T 23-10-2018 A0127_06550 941f8abdcb88f4fbaf13aecf5edb2d6d 509 Pfam PF01943 Polysaccharide biosynthesis protein 12 279 2.5E-29 T 23-10-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 A0127_06550 941f8abdcb88f4fbaf13aecf5edb2d6d 509 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 342 477 4.1E-23 T 23-10-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain A0127_03465 9978f9a676233bd5a1c71e2ea14e54fd 80 Gene3D G3DSA:3.30.70.920 1 73 5.2E-22 T 23-10-2018 A0127_03465 9978f9a676233bd5a1c71e2ea14e54fd 80 SUPERFAMILY SSF54909 1 77 2.68E-17 T 23-10-2018 IPR011008 Dimeric alpha-beta barrel A0127_03465 9978f9a676233bd5a1c71e2ea14e54fd 80 Pfam PF01037 Lrp/AsnC ligand binding domain 6 77 1.5E-16 T 23-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain A0127_04455 2efc24bcb5d692bcae4b384e5d9e4cbe 429 Gene3D G3DSA:3.30.2290.10 1 221 1.1E-16 T 23-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal A0127_04455 2efc24bcb5d692bcae4b384e5d9e4cbe 429 Pfam PF01523 Putative modulator of DNA gyrase 18 305 7.2E-51 T 23-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 A0127_04455 2efc24bcb5d692bcae4b384e5d9e4cbe 429 SUPERFAMILY SSF111283 2 424 4.58E-83 T 23-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 A0127_03005 e098883a46318d0d5221f2ed245b2f5d 650 SUPERFAMILY SSF55486 435 649 2.86E-17 T 23-10-2018 A0127_03005 e098883a46318d0d5221f2ed245b2f5d 650 Gene3D G3DSA:1.10.390.60 421 647 1.7E-17 T 23-10-2018 A0127_03005 e098883a46318d0d5221f2ed245b2f5d 650 Pfam PF01433 Peptidase family M1 domain 499 639 4.6E-9 T 23-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 A0127_04270 e12494528ee7386da353e3828c6f55ad 153 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 1 127 8.9E-10 T 23-10-2018 IPR007404 LexA-binding, inner membrane-associated putative hydrolase A0127_09965 1f0405797f297f2ae3c926e36624f77b 276 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 209 268 4.7E-9 T 23-10-2018 IPR002831 Transcription regulator TrmB, N-terminal A0127_09965 1f0405797f297f2ae3c926e36624f77b 276 SUPERFAMILY SSF46785 202 268 7.93E-13 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A0127_09965 1f0405797f297f2ae3c926e36624f77b 276 Gene3D G3DSA:1.10.10.10 191 269 2.2E-11 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A0127_03855 a70e7e2f2fedcf46c1b0265308e51681 293 Gene3D G3DSA:3.40.50.300 2 229 1.0E-63 T 23-10-2018 A0127_03855 a70e7e2f2fedcf46c1b0265308e51681 293 SUPERFAMILY SSF52540 4 219 4.79E-60 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_03855 a70e7e2f2fedcf46c1b0265308e51681 293 Pfam PF00005 ABC transporter 19 158 5.2E-25 T 23-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 A0127_03855 a70e7e2f2fedcf46c1b0265308e51681 293 SMART SM00382 28 214 1.3E-12 T 23-10-2018 IPR003593 AAA+ ATPase domain A0127_05125 2070ca4ec34ae706ae0a70c455e41f38 275 Pfam PF00892 EamA-like transporter family 144 272 5.0E-16 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A0127_05125 2070ca4ec34ae706ae0a70c455e41f38 275 Pfam PF00892 EamA-like transporter family 6 130 5.0E-20 T 23-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 A0127_05125 2070ca4ec34ae706ae0a70c455e41f38 275 SUPERFAMILY SSF103481 182 272 6.28E-8 T 23-10-2018 A0127_05125 2070ca4ec34ae706ae0a70c455e41f38 275 SUPERFAMILY SSF103481 38 133 1.23E-15 T 23-10-2018 A0127_03890 aff6f401e57cbe4da18a22f61d774d07 341 SUPERFAMILY SSF48452 52 239 8.72E-24 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A0127_03890 aff6f401e57cbe4da18a22f61d774d07 341 Gene3D G3DSA:1.25.40.10 127 332 1.2E-17 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A0127_03890 aff6f401e57cbe4da18a22f61d774d07 341 SMART SM00028 211 244 69.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A0127_03890 aff6f401e57cbe4da18a22f61d774d07 341 SMART SM00028 174 207 19.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A0127_03890 aff6f401e57cbe4da18a22f61d774d07 341 SMART SM00028 134 167 9.3 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A0127_03890 aff6f401e57cbe4da18a22f61d774d07 341 SMART SM00028 93 126 0.0018 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A0127_03890 aff6f401e57cbe4da18a22f61d774d07 341 SMART SM00028 55 88 19.0 T 23-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 A0127_03890 aff6f401e57cbe4da18a22f61d774d07 341 Gene3D G3DSA:1.25.40.10 37 126 1.4E-11 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A0127_03890 aff6f401e57cbe4da18a22f61d774d07 341 Pfam PF13424 Tetratricopeptide repeat 58 121 1.1E-8 T 23-10-2018 A0127_03890 aff6f401e57cbe4da18a22f61d774d07 341 Pfam PF13424 Tetratricopeptide repeat 133 203 2.1E-10 T 23-10-2018 A0127_00530 f654066542f30e19432c7657e1fed07e 248 Gene3D G3DSA:3.40.50.300 2 242 8.9E-48 T 23-10-2018 A0127_00530 f654066542f30e19432c7657e1fed07e 248 SUPERFAMILY SSF52540 1 244 3.2E-47 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_00530 f654066542f30e19432c7657e1fed07e 248 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 3 221 7.6E-19 T 23-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain A0127_00220 526bd80834f4cf86f3e169387f20568f 317 Gene3D G3DSA:3.100.10.20 1 80 5.2E-28 T 23-10-2018 A0127_00220 526bd80834f4cf86f3e169387f20568f 317 Gene3D G3DSA:1.20.120.920 82 314 5.0E-58 T 23-10-2018 A0127_00220 526bd80834f4cf86f3e169387f20568f 317 Pfam PF01867 CRISPR associated protein Cas1 5 270 3.9E-74 T 23-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 A0127_00220 526bd80834f4cf86f3e169387f20568f 317 TIGRFAM TIGR00287 cas1: CRISPR-associated endonuclease Cas1 5 311 8.5E-81 T 23-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 A0127_00220 526bd80834f4cf86f3e169387f20568f 317 TIGRFAM TIGR03641 cas1_HMARI: CRISPR-associated endonuclease Cas1, subtype I-B/HMARI/TNEAP 4 317 4.1E-123 T 23-10-2018 IPR019858 CRISPR-associated protein Cas1, HMARI/TNEAP subtype GO:0004520|GO:0043571|GO:0046872 A0127_00220 526bd80834f4cf86f3e169387f20568f 317 Hamap MF_01470 CRISPR-associated endonuclease Cas1 [cas1]. 2 302 24.195 T 23-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 A0127_06295 6a7ddf57ea8facd25e4259dab4964a1a 243 Gene3D G3DSA:3.30.2010.10 129 223 1.4E-18 T 23-10-2018 A0127_06295 6a7ddf57ea8facd25e4259dab4964a1a 243 Pfam PF01863 Protein of unknown function DUF45 21 221 4.2E-48 T 23-10-2018 IPR002725 Protein of unknown function DUF45 A0127_01280 77ee6903f75595734d53ae374adbe947 396 SUPERFAMILY SSF56349 129 377 3.77E-9 T 23-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 A0127_01280 77ee6903f75595734d53ae374adbe947 396 Gene3D G3DSA:1.10.443.10 217 386 8.7E-39 T 23-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 A0127_01280 77ee6903f75595734d53ae374adbe947 396 Pfam PF16795 Archaeal phage integrase 221 382 4.9E-36 T 23-10-2018 IPR031857 Integrase SSV1, C-terminal A0127_00345 0e648576c6db4d0caa0d4d4a485311db 75 Gene3D G3DSA:2.30.30.90 12 75 4.2E-20 T 23-10-2018 IPR038157 Ferrous iron transporter, core domain A0127_00345 0e648576c6db4d0caa0d4d4a485311db 75 Pfam PF04023 FeoA domain 3 73 2.4E-19 T 23-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 A0127_00345 0e648576c6db4d0caa0d4d4a485311db 75 SMART SM00899 3 74 7.0E-21 T 23-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 A0127_00345 0e648576c6db4d0caa0d4d4a485311db 75 SUPERFAMILY SSF50037 5 74 3.2E-17 T 23-10-2018 IPR008988 Transcriptional repressor, C-terminal A0127_04775 500f33d6994d3a83d1ba5f50319e46a3 151 Hamap MF_00620 Putative transcriptional regulatory protein . 1 133 30.482 T 23-10-2018 IPR018384 DNA-binding protein Tfx, euryarchaeota GO:0003677 A0127_04775 500f33d6994d3a83d1ba5f50319e46a3 151 Gene3D G3DSA:3.30.1190.10 15 133 8.7E-39 T 23-10-2018 IPR036657 DNA-binding protein Tfx superfamily, archaea GO:0003677 A0127_04775 500f33d6994d3a83d1ba5f50319e46a3 151 TIGRFAM TIGR00721 tfx: DNA-binding protein, Tfx family 1 134 8.5E-60 T 23-10-2018 IPR004645 DNA-binding protein Tfx, archaea GO:0003677 A0127_04775 500f33d6994d3a83d1ba5f50319e46a3 151 PIRSF PIRSF004932 1 149 4.3E-70 T 23-10-2018 IPR018384 DNA-binding protein Tfx, euryarchaeota GO:0003677 A0127_04775 500f33d6994d3a83d1ba5f50319e46a3 151 Pfam PF14601 DNA_binding protein, TFX, C-term 50 130 3.8E-25 T 23-10-2018 IPR029291 DNA binding protein Tfx, C-terminal A0127_04775 500f33d6994d3a83d1ba5f50319e46a3 151 SUPERFAMILY SSF89915 15 130 1.96E-24 T 23-10-2018 IPR036657 DNA-binding protein Tfx superfamily, archaea GO:0003677 A0127_04775 500f33d6994d3a83d1ba5f50319e46a3 151 Pfam PF04545 Sigma-70, region 4 5 47 2.0E-7 T 23-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 A0127_04775 500f33d6994d3a83d1ba5f50319e46a3 151 SMART SM00421 2 59 0.0041 T 23-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 A0127_10120 3c217194dd0ad203f9ec01e230ab609c 373 Pfam PF02687 FtsX-like permease family 278 367 6.9E-11 T 23-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 A0127_10120 3c217194dd0ad203f9ec01e230ab609c 373 Pfam PF12704 MacB-like periplasmic core domain 15 210 6.2E-9 T 23-10-2018 IPR025857 MacB-like periplasmic core domain A0127_09865 ddd3e912f4729e0d6bd17b76786523c8 374 Gene3D G3DSA:3.40.720.10 1 372 1.0E-55 T 23-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 A0127_09865 ddd3e912f4729e0d6bd17b76786523c8 374 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 6 322 4.5E-47 T 23-10-2018 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 A0127_09865 ddd3e912f4729e0d6bd17b76786523c8 374 SUPERFAMILY SSF53649 2 359 1.89E-76 T 23-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 A0127_06635 4c5c6901508ecb6fc2eae047c3c219db 324 Gene3D G3DSA:3.90.550.10 1 243 9.4E-45 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A0127_06635 4c5c6901508ecb6fc2eae047c3c219db 324 SUPERFAMILY SSF53448 5 217 9.29E-47 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A0127_06635 4c5c6901508ecb6fc2eae047c3c219db 324 Pfam PF00535 Glycosyl transferase family 2 7 151 9.9E-27 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A0127_00645 4e45276834007ec4a9b77cfdad003860 420 TIGRFAM TIGR00375 TIGR00375: TIGR00375 family protein 5 379 2.2E-130 T 23-10-2018 IPR005287 Conserved hypothetical protein CHP00375 A0127_00645 4e45276834007ec4a9b77cfdad003860 420 Pfam PF13263 PHP-associated 175 227 1.1E-4 T 23-10-2018 A0127_00645 4e45276834007ec4a9b77cfdad003860 420 SUPERFAMILY SSF89550 4 230 1.1E-15 T 23-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 A0127_00645 4e45276834007ec4a9b77cfdad003860 420 Gene3D G3DSA:3.20.20.140 2 234 2.9E-17 T 23-10-2018 A0127_02040 3dd0dc11a530a3f037c6dbc4bb7c850a 177 Pfam PF13302 Acetyltransferase (GNAT) domain 16 149 2.1E-28 T 23-10-2018 IPR000182 GNAT domain A0127_02040 3dd0dc11a530a3f037c6dbc4bb7c850a 177 SUPERFAMILY SSF55729 2 171 1.98E-41 T 23-10-2018 IPR016181 Acyl-CoA N-acyltransferase A0127_02040 3dd0dc11a530a3f037c6dbc4bb7c850a 177 Gene3D G3DSA:3.40.630.30 1 177 5.4E-44 T 23-10-2018 A0127_07560 703b28d7f469d9a91cc6bf33a30ad6dd 126 SUPERFAMILY SSF52042 5 126 7.59E-47 T 23-10-2018 IPR036351 Ribosomal protein L32e superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_07560 703b28d7f469d9a91cc6bf33a30ad6dd 126 Hamap MF_00810 50S ribosomal protein L32e [rpl32e]. 2 126 32.061 T 23-10-2018 IPR023654 Ribosomal protein L32e, archaeal GO:0003735|GO:0005840|GO:0006412 A0127_07560 703b28d7f469d9a91cc6bf33a30ad6dd 126 ProDom PD003823 RIBOSOMAL L32 RIBONUCLEOPROTEIN 60S L32E 50S L32 STRAIN CHROMOSOME DIRECT 21 126 1.0E-55 T 23-10-2018 IPR001515 Ribosomal protein L32e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_07560 703b28d7f469d9a91cc6bf33a30ad6dd 126 SMART SM01393 18 125 2.9E-63 T 23-10-2018 IPR001515 Ribosomal protein L32e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_07560 703b28d7f469d9a91cc6bf33a30ad6dd 126 Pfam PF01655 Ribosomal protein L32 18 125 4.3E-41 T 23-10-2018 IPR001515 Ribosomal protein L32e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_07560 703b28d7f469d9a91cc6bf33a30ad6dd 126 ProSitePatterns PS00580 Ribosomal protein L32e signature. 21 43 - T 23-10-2018 IPR018263 Ribosomal protein L32e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_03470 d819ecd8061ab6ed7598a0736af7f1a8 706 PIRSF PIRSF002741 194 419 4.1E-9 T 23-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 A0127_03470 d819ecd8061ab6ed7598a0736af7f1a8 706 PIRSF PIRSF002741 98 197 7.9E-4 T 23-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 A0127_03470 d819ecd8061ab6ed7598a0736af7f1a8 706 PIRSF PIRSF002741 429 702 9.8E-56 T 23-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 A0127_03470 d819ecd8061ab6ed7598a0736af7f1a8 706 SUPERFAMILY SSF53850 213 694 4.65E-87 T 23-10-2018 A0127_03470 d819ecd8061ab6ed7598a0736af7f1a8 706 SUPERFAMILY SSF53850 115 194 5.79E-7 T 23-10-2018 A0127_03470 d819ecd8061ab6ed7598a0736af7f1a8 706 Gene3D G3DSA:3.10.105.10 537 703 7.3E-44 T 23-10-2018 A0127_03470 d819ecd8061ab6ed7598a0736af7f1a8 706 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 260 695 7.2E-70 T 23-10-2018 IPR000914 Solute-binding protein family 5 domain A0127_03470 d819ecd8061ab6ed7598a0736af7f1a8 706 Gene3D G3DSA:3.40.190.10 199 534 9.8E-45 T 23-10-2018 A0127_02775 a48be93bbbbe3034b182fa85f9929c6a 439 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 228 244 1.9E-23 T 23-10-2018 A0127_02775 a48be93bbbbe3034b182fa85f9929c6a 439 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 3 22 1.9E-23 T 23-10-2018 A0127_02775 a48be93bbbbe3034b182fa85f9929c6a 439 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 98 116 1.9E-23 T 23-10-2018 A0127_02775 a48be93bbbbe3034b182fa85f9929c6a 439 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 145 163 1.9E-23 T 23-10-2018 A0127_02775 a48be93bbbbe3034b182fa85f9929c6a 439 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 253 275 1.9E-23 T 23-10-2018 A0127_02775 a48be93bbbbe3034b182fa85f9929c6a 439 SUPERFAMILY SSF51905 1 191 1.3E-48 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A0127_02775 a48be93bbbbe3034b182fa85f9929c6a 439 Gene3D G3DSA:3.50.50.60 2 331 2.7E-148 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A0127_02775 a48be93bbbbe3034b182fa85f9929c6a 439 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 324 423 1.0E-16 T 23-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 A0127_02775 a48be93bbbbe3034b182fa85f9929c6a 439 SUPERFAMILY SSF51905 142 307 2.35E-34 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A0127_02775 a48be93bbbbe3034b182fa85f9929c6a 439 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 268 275 2.4E-18 T 23-10-2018 A0127_02775 a48be93bbbbe3034b182fa85f9929c6a 439 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 2 24 2.4E-18 T 23-10-2018 A0127_02775 a48be93bbbbe3034b182fa85f9929c6a 439 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 145 170 2.4E-18 T 23-10-2018 A0127_02775 a48be93bbbbe3034b182fa85f9929c6a 439 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 229 243 2.4E-18 T 23-10-2018 A0127_02775 a48be93bbbbe3034b182fa85f9929c6a 439 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 296 1.2E-69 T 23-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 A0127_02775 a48be93bbbbe3034b182fa85f9929c6a 439 SUPERFAMILY SSF55424 316 438 1.01E-27 T 23-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 A0127_02775 a48be93bbbbe3034b182fa85f9929c6a 439 Gene3D G3DSA:3.50.50.60 107 431 2.7E-148 T 23-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily A0127_00755 a473d20e0e64f7699e8239bc04898362 120 Pfam PF00072 Response regulator receiver domain 4 114 5.8E-33 T 23-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A0127_00755 a473d20e0e64f7699e8239bc04898362 120 SMART SM00448 2 114 1.4E-38 T 23-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 A0127_00755 a473d20e0e64f7699e8239bc04898362 120 SUPERFAMILY SSF52172 1 119 2.56E-40 T 23-10-2018 IPR011006 CheY-like superfamily A0127_00755 a473d20e0e64f7699e8239bc04898362 120 Gene3D G3DSA:3.40.50.2300 1 120 5.9E-41 T 23-10-2018 A0127_05965 da8096782a477d0006dbe95a39039db7 398 Pfam PF01882 Protein of unknown function DUF58 178 257 7.3E-23 T 23-10-2018 IPR002881 Domain of unknown function DUF58 A0127_08715 1a2dd0735b70a021de773073d298be21 78 Pfam PF07441 SigmaK-factor processing regulatory protein BofA 9 77 1.0E-6 T 23-10-2018 IPR010001 SigmaK-factor processing regulatory BofA A0127_09675 09ad879d385b556a8bc7da4abc4f88b0 60 SUPERFAMILY SSF54814 11 58 3.14E-8 T 23-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 A0127_09675 09ad879d385b556a8bc7da4abc4f88b0 60 Pfam PF07650 KH domain 4 56 5.8E-5 T 23-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_09675 09ad879d385b556a8bc7da4abc4f88b0 60 Gene3D G3DSA:3.30.300.20 4 60 8.5E-8 T 23-10-2018 IPR015946 K homology domain-like, alpha/beta A0127_08755 d67497badb84a51034834f6940f630e9 367 SUPERFAMILY SSF53756 1 320 1.95E-24 T 23-10-2018 A0127_08755 d67497badb84a51034834f6940f630e9 367 PIRSF PIRSF005357 1 345 5.8E-117 T 23-10-2018 IPR007152 Protein of unknown function DUF354 A0127_08755 d67497badb84a51034834f6940f630e9 367 Pfam PF04007 Protein of unknown function (DUF354) 1 338 3.5E-97 T 23-10-2018 IPR007152 Protein of unknown function DUF354 A0127_05065 a58b171cd175244b569e8759aa7b85b9 185 Hamap MF_01909 Transcription factor E [tfe]. 3 166 26.976 T 23-10-2018 IPR016481 Transcription factor TFE, archaea GO:0006355 A0127_05065 a58b171cd175244b569e8759aa7b85b9 185 PIRSF PIRSF006373 1 180 2.5E-71 T 23-10-2018 IPR016481 Transcription factor TFE, archaea GO:0006355 A0127_05065 a58b171cd175244b569e8759aa7b85b9 185 SMART SM00531 19 158 8.5E-53 T 23-10-2018 IPR002853 Transcription initiation factor IIE subunit alpha, N-terminal GO:0006367 Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-674695|Reactome: R-HSA-6807505|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-76042 A0127_05065 a58b171cd175244b569e8759aa7b85b9 185 Gene3D G3DSA:1.10.10.10 3 87 7.5E-27 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A0127_05065 a58b171cd175244b569e8759aa7b85b9 185 Pfam PF02002 TFIIE alpha subunit 10 110 1.7E-24 T 23-10-2018 IPR024550 TFIIEalpha/SarR/Rpc3 HTH domain Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-674695|Reactome: R-HSA-6807505|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-76042 A0127_05065 a58b171cd175244b569e8759aa7b85b9 185 TIGRFAM TIGR00373 TIGR00373: transcription factor E 10 164 1.2E-47 T 23-10-2018 IPR016481 Transcription factor TFE, archaea GO:0006355 A0127_05065 a58b171cd175244b569e8759aa7b85b9 185 SUPERFAMILY SSF46785 6 87 1.29E-23 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A0127_02015 481995c4a078539f4664afcb42040863 170 PIRSF PIRSF006443 1 170 5.4E-54 T 23-10-2018 IPR012245 Molybdenum cofactor biosynthesis protein MoaB GO:0006777 A0127_02015 481995c4a078539f4664afcb42040863 170 SMART SM00852 17 164 1.5E-25 T 23-10-2018 IPR001453 MoaB/Mog domain A0127_02015 481995c4a078539f4664afcb42040863 170 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 14 158 1.3E-33 T 23-10-2018 IPR001453 MoaB/Mog domain A0127_02015 481995c4a078539f4664afcb42040863 170 Gene3D G3DSA:3.40.980.10 12 169 2.7E-43 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily A0127_02015 481995c4a078539f4664afcb42040863 170 Pfam PF00994 Probable molybdopterin binding domain 17 158 1.3E-32 T 23-10-2018 IPR001453 MoaB/Mog domain A0127_02015 481995c4a078539f4664afcb42040863 170 SUPERFAMILY SSF53218 13 167 1.31E-39 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily A0127_08080 426d4d2795a1d009c67fbc19699a663c 67 Pfam PF00808 Histone-like transcription factor (CBF/NF-Y) and archaeal histone 2 65 3.5E-21 T 23-10-2018 IPR003958 Transcription factor CBF/NF-Y/archaeal histone domain A0127_08080 426d4d2795a1d009c67fbc19699a663c 67 Gene3D G3DSA:1.10.20.10 1 67 2.3E-24 T 23-10-2018 IPR009072 Histone-fold GO:0046982 A0127_08080 426d4d2795a1d009c67fbc19699a663c 67 SUPERFAMILY SSF47113 3 66 2.75E-20 T 23-10-2018 IPR009072 Histone-fold GO:0046982 A0127_03190 779dae123f9a5b38c04db682c0b6dbc0 308 Pfam PF01874 ATP:dephospho-CoA triphosphoribosyl transferase 9 285 4.1E-54 T 23-10-2018 IPR002736 Triphosphoribosyl-dephospho-CoA protein GO:0005524|GO:0016310|GO:0046917 MetaCyc: PWY-5796 A0127_03190 779dae123f9a5b38c04db682c0b6dbc0 308 Gene3D G3DSA:1.10.4200.10 25 293 1.3E-61 T 23-10-2018 A0127_02765 0fa70342bc6412d36bb4f5371efe4fce 429 PIRSF PIRSF037420 66 427 5.7E-63 T 23-10-2018 IPR017200 Coenzyme PQQ synthesis protein E A0127_02765 0fa70342bc6412d36bb4f5371efe4fce 429 SUPERFAMILY SSF102114 78 401 7.59E-58 T 23-10-2018 A0127_02765 0fa70342bc6412d36bb4f5371efe4fce 429 Pfam PF13186 Iron-sulfur cluster-binding domain 325 392 2.0E-10 T 23-10-2018 IPR023885 4Fe4S-binding SPASM domain A0127_02765 0fa70342bc6412d36bb4f5371efe4fce 429 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 325 419 2.0E-18 T 23-10-2018 IPR023885 4Fe4S-binding SPASM domain A0127_02765 0fa70342bc6412d36bb4f5371efe4fce 429 Pfam PF04055 Radical SAM superfamily 85 240 2.9E-20 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A0127_02765 0fa70342bc6412d36bb4f5371efe4fce 429 Pfam PF13394 4Fe-4S single cluster domain 86 164 3.9E-8 T 23-10-2018 A0127_02765 0fa70342bc6412d36bb4f5371efe4fce 429 SMART SM00729 79 278 0.0013 T 23-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 A0127_02765 0fa70342bc6412d36bb4f5371efe4fce 429 Gene3D G3DSA:3.20.20.70 77 398 1.4E-51 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A0127_05230 9a61306d5966d8be2af2bfffee5ad41d 224 SUPERFAMILY SSF109755 25 221 1.15E-19 T 23-10-2018 A0127_05230 9a61306d5966d8be2af2bfffee5ad41d 224 TIGRFAM TIGR00153 TIGR00153: TIGR00153 family protein 5 222 2.4E-34 T 23-10-2018 IPR002727 Protein of unknown function DUF47 A0127_05230 9a61306d5966d8be2af2bfffee5ad41d 224 Gene3D G3DSA:1.20.58.220 1 224 4.1E-50 T 23-10-2018 IPR038078 PhoU-like domain superfamily A0127_05230 9a61306d5966d8be2af2bfffee5ad41d 224 Pfam PF01865 Protein of unknown function DUF47 6 222 2.6E-45 T 23-10-2018 IPR018445 Putative phosphate transport regulator A0127_01115 827b730e74bdd0aea87a7aa717796abe 700 SUPERFAMILY SSF52540 384 589 8.36E-14 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_01115 827b730e74bdd0aea87a7aa717796abe 700 Pfam PF07728 AAA domain (dynein-related subfamily) 398 579 4.9E-16 T 23-10-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 A0127_01115 827b730e74bdd0aea87a7aa717796abe 700 SMART SM00382 394 589 2.8E-8 T 23-10-2018 IPR003593 AAA+ ATPase domain A0127_00965 47468f24e42d57cc72dba0c6f01ac201 115 Pfam PF13192 Thioredoxin domain 33 106 4.0E-10 T 23-10-2018 IPR012336 Thioredoxin-like fold A0127_00965 47468f24e42d57cc72dba0c6f01ac201 115 SUPERFAMILY SSF52833 17 111 9.26E-16 T 23-10-2018 IPR036249 Thioredoxin-like superfamily A0127_00965 47468f24e42d57cc72dba0c6f01ac201 115 Gene3D G3DSA:3.40.30.10 22 109 7.9E-17 T 23-10-2018 A0127_02640 6f65a4005180625358dccd5d5799af83 132 Gene3D G3DSA:3.10.180.10 1 131 5.4E-43 T 23-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A0127_02640 6f65a4005180625358dccd5d5799af83 132 TIGRFAM TIGR03081 metmalonyl_epim: methylmalonyl-CoA epimerase 4 130 5.9E-53 T 23-10-2018 IPR017515 Methylmalonyl-CoA epimerase KEGG: 00280+5.1.99.1|KEGG: 00630+5.1.99.1|KEGG: 00640+5.1.99.1|KEGG: 00720+5.1.99.1|MetaCyc: PWY-5741|MetaCyc: PWY-5743|MetaCyc: PWY-5789|MetaCyc: PWY-6728|MetaCyc: PWY-7384|MetaCyc: PWY-7854|Reactome: R-HSA-71032 A0127_02640 6f65a4005180625358dccd5d5799af83 132 SUPERFAMILY SSF54593 1 131 9.93E-35 T 23-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase A0127_02640 6f65a4005180625358dccd5d5799af83 132 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 115 7.5E-25 T 23-10-2018 A0127_00135 9196d1837ce1a206f8d011fcba8fb02a 91 SMART SM00966 6 51 9.0E-13 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 A0127_00135 9196d1837ce1a206f8d011fcba8fb02a 91 Gene3D G3DSA:2.10.260.10 3 46 2.8E-9 T 23-10-2018 A0127_00135 9196d1837ce1a206f8d011fcba8fb02a 91 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 5 47 1.1E-11 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 A0127_00135 9196d1837ce1a206f8d011fcba8fb02a 91 SUPERFAMILY SSF89447 4 47 4.84E-11 T 23-10-2018 IPR037914 SpoVT-AbrB domain superfamily A0127_00135 9196d1837ce1a206f8d011fcba8fb02a 91 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 7 50 6.0E-13 T 23-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 A0127_05715 34aa2de7d9a86f53dcc449c23917f5a1 227 Gene3D G3DSA:3.40.50.11570 6 219 3.6E-51 T 23-10-2018 A0127_05715 34aa2de7d9a86f53dcc449c23917f5a1 227 Pfam PF03192 Pyrococcus protein of unknown function, DUF257 11 214 5.4E-49 T 23-10-2018 IPR005489 Protein of unknown function DUF257 A0127_00630 29254f2e5f101e89cd856b6e8ac128d8 242 SUPERFAMILY SSF88713 4 232 5.84E-28 T 23-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 A0127_00630 29254f2e5f101e89cd856b6e8ac128d8 242 Pfam PF01522 Polysaccharide deacetylase 4 126 3.5E-15 T 23-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 A0127_00630 29254f2e5f101e89cd856b6e8ac128d8 242 Gene3D G3DSA:3.20.20.370 1 239 1.1E-36 T 23-10-2018 A0127_02760 7389dd32a678294e0d9cee9624f49f85 146 TIGRFAM TIGR00305 TIGR00305: putative toxin-antitoxin system toxin component, PIN family 5 116 7.6E-26 T 23-10-2018 IPR002850 PIN family, putative toxin-antitoxin system toxin component A0127_02760 7389dd32a678294e0d9cee9624f49f85 146 Pfam PF13470 PIN domain 5 115 1.4E-12 T 23-10-2018 IPR002716 PIN domain A0127_02760 7389dd32a678294e0d9cee9624f49f85 146 SUPERFAMILY SSF88723 4 122 5.23E-8 T 23-10-2018 IPR029060 PIN-like domain superfamily A0127_01440 4e2e00997507df13ae1f4ca81783e021 143 Gene3D G3DSA:1.20.120.1630 2 142 3.6E-24 T 23-10-2018 A0127_01440 4e2e00997507df13ae1f4ca81783e021 143 Pfam PF04191 Phospholipid methyltransferase 41 127 1.2E-5 T 23-10-2018 IPR007318 Phospholipid methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825|Reactome: R-HSA-1483191 A0127_04075 ff2622c5319bdf0878a36f00f7f0340c 121 SUPERFAMILY SSF46785 17 118 7.23E-18 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A0127_04075 ff2622c5319bdf0878a36f00f7f0340c 121 Gene3D G3DSA:1.10.10.10 19 86 4.9E-15 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A0127_04075 ff2622c5319bdf0878a36f00f7f0340c 121 Pfam PF03965 Penicillinase repressor 19 113 1.3E-17 T 23-10-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 A0127_05400 d7a0e7e48f4b00928ee6425e90782842 199 Gene3D G3DSA:1.10.1760.20 33 194 8.2E-48 T 23-10-2018 A0127_05400 d7a0e7e48f4b00928ee6425e90782842 199 Pfam PF07155 ECF-type riboflavin transporter, S component 36 190 2.6E-43 T 23-10-2018 IPR009825 ECF transporter, substrate-specific component-like GO:0016020 A0127_09895 312a2eb52a6faac832f2113cdca692c1 250 SUPERFAMILY SSF53448 2 244 1.06E-37 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A0127_09895 312a2eb52a6faac832f2113cdca692c1 250 Pfam PF00535 Glycosyl transferase family 2 4 144 1.0E-27 T 23-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 A0127_09895 312a2eb52a6faac832f2113cdca692c1 250 Gene3D G3DSA:3.90.550.10 1 244 3.3E-45 T 23-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases A0127_04990 5f2f5b40738821d79e7094b6698507ff 320 Pfam PF01384 Phosphate transporter family 19 307 8.1E-69 T 23-10-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 A0127_09395 4b5578f7be3a0cafc0d0f3fbed38bac8 254 Pfam PF04039 Domain related to MnhB subunit of Na+/H+ antiporter 115 239 1.3E-15 T 23-10-2018 IPR007182 Na+/H+ antiporter MnhB subunit-related protein A0127_03830 a1c044efdc10efd64817a6702c70ce09 129 Gene3D G3DSA:2.40.50.140 65 129 4.4E-16 T 23-10-2018 A0127_03830 a1c044efdc10efd64817a6702c70ce09 129 SUPERFAMILY SSF141322 63 126 2.09E-8 T 23-10-2018 A0127_03830 a1c044efdc10efd64817a6702c70ce09 129 Pfam PF01957 NfeD-like C-terminal, partner-binding 17 126 6.4E-13 T 23-10-2018 IPR002810 NfeD-like, C-terminal domain A0127_00370 57570c5e21fe83e453f5320b178bd35b 121 Gene3D G3DSA:3.40.50.11630 1 121 3.9E-59 T 23-10-2018 A0127_01220 3a3ccc863605d5d2fd7d486cf2d12c2f 293 Pfam PF03547 Membrane transport protein 5 115 2.2E-9 T 23-10-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 A0127_01220 3a3ccc863605d5d2fd7d486cf2d12c2f 293 Pfam PF03547 Membrane transport protein 148 284 1.3E-7 T 23-10-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 A0127_00355 41dad56390e674973376135d3d88a76b 88 SUPERFAMILY SSF46785 7 49 1.98E-6 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A0127_00355 41dad56390e674973376135d3d88a76b 88 Gene3D G3DSA:1.10.10.10 1 58 4.2E-7 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A0127_00355 41dad56390e674973376135d3d88a76b 88 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 9 49 6.8E-6 T 23-10-2018 IPR002831 Transcription regulator TrmB, N-terminal A0127_03515 d68d287d7f8fa4f50f6363aef5ac26e3 423 Gene3D G3DSA:3.40.1710.10 41 202 1.2E-37 T 23-10-2018 A0127_03515 d68d287d7f8fa4f50f6363aef5ac26e3 423 Pfam PF12698 ABC-2 family transporter protein 19 403 2.4E-36 T 23-10-2018 A0127_03745 cd96a846726bb500e0807157748b8308 188 SUPERFAMILY SSF102198 2 187 1.01E-54 T 23-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 A0127_03745 cd96a846726bb500e0807157748b8308 188 Gene3D G3DSA:3.50.30.50 1 187 3.0E-57 T 23-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 A0127_03745 cd96a846726bb500e0807157748b8308 188 Pfam PF04199 Putative cyclase 3 134 2.0E-23 T 23-10-2018 IPR007325 Kynurenine formamidase/cyclase-like GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 A0127_10320 5f20f709a2f0c0d9472f9646a08e3c3a 91 Pfam PF11537 Protein of unknown function (DUF3227) 1 87 2.8E-31 T 23-10-2018 IPR021609 Protein of unknown function DUF3227 A0127_10320 5f20f709a2f0c0d9472f9646a08e3c3a 91 Gene3D G3DSA:1.10.1200.200 1 91 4.6E-36 T 23-10-2018 A0127_03715 39140cdd8213cbbaed32874ab13086f3 247 SUPERFAMILY SSF48371 27 220 7.2E-23 T 23-10-2018 IPR016024 Armadillo-type fold A0127_03715 39140cdd8213cbbaed32874ab13086f3 247 Gene3D G3DSA:1.25.10.10 1 247 3.5E-68 T 23-10-2018 IPR011989 Armadillo-like helical A0127_03715 39140cdd8213cbbaed32874ab13086f3 247 SMART SM01349 10 229 0.004 T 23-10-2018 IPR034085 TOG domain A0127_03715 39140cdd8213cbbaed32874ab13086f3 247 Pfam PF02985 HEAT repeat 179 207 2.1E-5 T 23-10-2018 IPR000357 HEAT repeat GO:0005515 A0127_09920 a0166fdfdb1e0d5753d0d7a69707aa53 126 SUPERFAMILY SSF46785 4 112 3.2E-21 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A0127_09920 a0166fdfdb1e0d5753d0d7a69707aa53 126 Pfam PF01475 Ferric uptake regulator family 12 122 1.4E-19 T 23-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 A0127_09920 a0166fdfdb1e0d5753d0d7a69707aa53 126 Gene3D G3DSA:1.10.10.10 2 82 3.1E-18 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A0127_03480 1424563136417ccb13a6145c751032a8 393 SUPERFAMILY SSF161098 136 355 5.49E-30 T 23-10-2018 IPR035906 MetI-like superfamily A0127_03480 1424563136417ccb13a6145c751032a8 393 Gene3D G3DSA:1.10.3720.10 131 371 1.4E-28 T 23-10-2018 IPR035906 MetI-like superfamily A0127_03480 1424563136417ccb13a6145c751032a8 393 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 159 374 2.0E-32 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A0127_03480 1424563136417ccb13a6145c751032a8 393 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 43 97 1.3E-5 T 23-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain A0127_02305 10a41fcbb03164a0810bf4f9c1253e89 232 Gene3D G3DSA:3.30.1490.20 39 116 5.1E-91 T 23-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 A0127_02305 10a41fcbb03164a0810bf4f9c1253e89 232 Gene3D G3DSA:3.30.470.20 21 230 5.1E-91 T 23-10-2018 A0127_02305 10a41fcbb03164a0810bf4f9c1253e89 232 Pfam PF13549 ATP-grasp domain 16 231 1.8E-83 T 23-10-2018 A0127_02305 10a41fcbb03164a0810bf4f9c1253e89 232 SUPERFAMILY SSF56059 23 232 1.08E-50 T 23-10-2018 A0127_06825 d89e0489e96d5412890960f4595dbb89 273 Gene3D G3DSA:3.40.50.1100 3 262 1.9E-66 T 23-10-2018 A0127_06825 d89e0489e96d5412890960f4595dbb89 273 Gene3D G3DSA:3.40.50.1100 19 120 1.9E-66 T 23-10-2018 A0127_06825 d89e0489e96d5412890960f4595dbb89 273 SUPERFAMILY SSF53686 3 268 4.98E-61 T 23-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme A0127_06825 d89e0489e96d5412890960f4595dbb89 273 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 3 249 4.6E-47 T 23-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme A0127_03775 c507f8ce46156454ec5223b8834e26de 249 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 70 242 2.4E-21 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A0127_03775 c507f8ce46156454ec5223b8834e26de 249 Gene3D G3DSA:1.10.3720.10 5 248 4.7E-64 T 23-10-2018 IPR035906 MetI-like superfamily A0127_03775 c507f8ce46156454ec5223b8834e26de 249 SUPERFAMILY SSF161098 6 241 1.44E-46 T 23-10-2018 IPR035906 MetI-like superfamily A0127_05910 119892737fd27a8068378b79c83a77b5 480 Pfam PF04415 Protein of unknown function (DUF515) 28 480 6.0E-206 T 23-10-2018 IPR007509 Protein of unknown function DUF515 A0127_00510 04503d654a5f4ef5fa5b06ace4380157 147 SUPERFAMILY SSF88723 12 142 1.49E-12 T 23-10-2018 IPR029060 PIN-like domain superfamily A0127_00510 04503d654a5f4ef5fa5b06ace4380157 147 Pfam PF10130 PIN domain 13 132 4.9E-23 T 23-10-2018 IPR002716 PIN domain A0127_00510 04503d654a5f4ef5fa5b06ace4380157 147 Gene3D G3DSA:3.40.50.1010 11 137 1.5E-6 T 23-10-2018 A0127_00510 04503d654a5f4ef5fa5b06ace4380157 147 TIGRFAM TIGR00305 TIGR00305: putative toxin-antitoxin system toxin component, PIN family 12 131 3.9E-8 T 23-10-2018 IPR002850 PIN family, putative toxin-antitoxin system toxin component A0127_04870 81d72b4900b81444856b4d6a53f57b07 192 SUPERFAMILY SSF57903 150 187 7.91E-5 T 23-10-2018 IPR011011 Zinc finger, FYVE/PHD-type A0127_07225 53160273ef1e1eb7929dd606fa933da1 102 Pfam PF01990 ATP synthase (F/14-kDa) subunit 3 89 5.7E-19 T 23-10-2018 IPR008218 ATPase, V1 complex, subunit F GO:0034220 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A0127_07225 53160273ef1e1eb7929dd606fa933da1 102 SUPERFAMILY SSF159468 3 100 5.23E-20 T 23-10-2018 IPR036906 ATPase, V1 complex, subunit F superfamily GO:0034220 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A0127_07225 53160273ef1e1eb7929dd606fa933da1 102 Hamap MF_00312 V-type ATP synthase subunit F [atpF]. 1 101 19.28 T 23-10-2018 IPR022944 ATPase, V1 complex, subunit F, bacterial/archaeal A0127_07225 53160273ef1e1eb7929dd606fa933da1 102 Gene3D G3DSA:3.40.50.10580 1 102 6.4E-35 T 23-10-2018 IPR036906 ATPase, V1 complex, subunit F superfamily GO:0034220 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 A0127_08290 8498f70c4e7d37e20d43c398fa436f2b 291 SUPERFAMILY SSF47240 58 190 1.1E-13 T 23-10-2018 IPR009078 Ferritin-like superfamily A0127_08290 8498f70c4e7d37e20d43c398fa436f2b 291 Pfam PF09968 Uncharacterized protein domain (DUF2202) 55 214 2.1E-64 T 23-10-2018 IPR019243 Domain of unknown function DUF2202 A0127_08290 8498f70c4e7d37e20d43c398fa436f2b 291 Gene3D G3DSA:1.20.1260.10 50 222 1.3E-69 T 23-10-2018 IPR012347 Ferritin-like A0127_08690 b35e3a48d291afff541b1d453c35f98d 434 Pfam PF02163 Peptidase family M50 321 364 2.4E-8 T 23-10-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 A0127_03540 31e02eb1d894757d08efda053670cefb 159 Pfam PF09946 Predicted membrane protein (DUF2178) 43 137 1.6E-17 T 23-10-2018 IPR019235 Protein of unknown function DUF2178, transmembrane A0127_01770 4872e5736b689e6492eccec3cd8159ca 235 SUPERFAMILY SSF55486 174 221 7.34E-9 T 23-10-2018 A0127_01770 4872e5736b689e6492eccec3cd8159ca 235 Pfam PF07998 Peptidase family M54 168 224 6.7E-20 T 23-10-2018 IPR012962 Peptidase M54, archaemetzincin GO:0008270 A0127_01770 4872e5736b689e6492eccec3cd8159ca 235 Pfam PF07998 Peptidase family M54 14 139 6.0E-16 T 23-10-2018 IPR012962 Peptidase M54, archaemetzincin GO:0008270 A0127_01770 4872e5736b689e6492eccec3cd8159ca 235 Gene3D G3DSA:3.40.390.10 76 230 5.2E-18 T 23-10-2018 IPR024079 Metallopeptidase, catalytic domain superfamily GO:0008237 A0127_04800 8e734699c29dd2e6b9fd27610413e15b 101 Pfam PF11491 Protein of unknown function (DUF3213) 15 98 5.1E-45 T 23-10-2018 IPR021583 Protein of unknown function DUF3213 A0127_04800 8e734699c29dd2e6b9fd27610413e15b 101 Gene3D G3DSA:3.30.70.1750 5 101 4.2E-34 T 23-10-2018 A0127_02905 f3b91087344897d0df5e32c0d76ed40c 386 SUPERFAMILY SSF103473 23 383 1.2E-29 T 23-10-2018 IPR036259 MFS transporter superfamily A0127_02905 f3b91087344897d0df5e32c0d76ed40c 386 Gene3D G3DSA:1.20.1250.20 18 384 4.0E-27 T 23-10-2018 A0127_09630 2a10e8d9945e581af8bf16491cb29897 257 SUPERFAMILY SSF103473 5 253 3.14E-22 T 23-10-2018 IPR036259 MFS transporter superfamily A0127_09630 2a10e8d9945e581af8bf16491cb29897 257 Pfam PF07690 Major Facilitator Superfamily 80 248 1.1E-8 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A0127_09630 2a10e8d9945e581af8bf16491cb29897 257 Gene3D G3DSA:1.20.1250.20 3 246 1.6E-12 T 23-10-2018 A0127_02280 55e4734eff63960d992eb85f4612875e 195 Pfam PF02517 CAAX protease self-immunity 107 184 1.4E-7 T 23-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 A0127_00805 a66ae49a4dbc063be68bce55d5ad3e09 230 Gene3D G3DSA:3.30.530.20 2 145 1.4E-5 T 23-10-2018 IPR023393 START-like domain superfamily A0127_01340 01d2036713dd9509eaccc56eeb53d152 173 Gene3D G3DSA:1.10.1760.20 1 172 2.7E-54 T 23-10-2018 A0127_01340 01d2036713dd9509eaccc56eeb53d152 173 PIRSF PIRSF016661 1 172 4.2E-46 T 23-10-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 A0127_01340 01d2036713dd9509eaccc56eeb53d152 173 Pfam PF02632 BioY family 27 168 4.6E-40 T 23-10-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 A0127_03700 cb01a6afa898948b049231230a3aae99 318 Pfam PF08241 Methyltransferase domain 163 259 3.9E-11 T 23-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 A0127_03700 cb01a6afa898948b049231230a3aae99 318 SUPERFAMILY SSF53335 132 304 3.54E-28 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A0127_03700 cb01a6afa898948b049231230a3aae99 318 Gene3D G3DSA:3.40.50.150 137 309 4.6E-25 T 23-10-2018 A0127_04590 2d1b1013010c341586d80e9989058471 104 Gene3D G3DSA:1.10.1200.200 7 100 2.2E-24 T 23-10-2018 A0127_04590 2d1b1013010c341586d80e9989058471 104 Pfam PF11537 Protein of unknown function (DUF3227) 8 96 2.1E-30 T 23-10-2018 IPR021609 Protein of unknown function DUF3227 A0127_02370 67630ae7d0c12eb2a06388fea5338fb5 270 Gene3D G3DSA:3.90.1640.20 1 269 6.1E-96 T 23-10-2018 A0127_02370 67630ae7d0c12eb2a06388fea5338fb5 270 Pfam PF14336 Domain of unknown function (DUF4392) 3 84 6.0E-13 T 23-10-2018 IPR025504 Domain of unknown function DUF4392 KEGG: 00471+4.2.1.48 A0127_02370 67630ae7d0c12eb2a06388fea5338fb5 270 Pfam PF14336 Domain of unknown function (DUF4392) 107 260 6.8E-52 T 23-10-2018 IPR025504 Domain of unknown function DUF4392 KEGG: 00471+4.2.1.48 A0127_05135 71055897baeaba91aac97b987ff3fe50 189 PIRSF PIRSF006006 1 180 1.6E-82 T 23-10-2018 IPR007501 Protein of unknown function DUF531 A0127_05135 71055897baeaba91aac97b987ff3fe50 189 Pfam PF04407 Protein of unknown function (DUF531) 4 171 1.6E-75 T 23-10-2018 IPR007501 Protein of unknown function DUF531 A0127_05635 58c7f2a75113697f941f234455514a72 1128 Pfam PF04465 Protein of unknown function (DUF499) 112 1125 0.0 T 23-10-2018 IPR007555 Protein of unknown function DUF499 A0127_00810 77d665969c416104d139638f07cb9665 163 Pfam PF01230 HIT domain 35 125 7.3E-15 T 23-10-2018 IPR001310 Histidine triad (HIT) protein A0127_00810 77d665969c416104d139638f07cb9665 163 SUPERFAMILY SSF54197 1 156 4.35E-47 T 23-10-2018 IPR036265 HIT-like superfamily A0127_00810 77d665969c416104d139638f07cb9665 163 Gene3D G3DSA:3.30.428.10 1 162 3.1E-59 T 23-10-2018 IPR036265 HIT-like superfamily A0127_08625 bc5b7fc9a599fdc4a902b515a977f2a4 128 SUPERFAMILY SSF46785 38 123 9.53E-23 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A0127_08625 bc5b7fc9a599fdc4a902b515a977f2a4 128 SMART SM00418 44 122 2.9E-25 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A0127_08625 bc5b7fc9a599fdc4a902b515a977f2a4 128 Gene3D G3DSA:1.10.10.10 13 123 1.7E-27 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A0127_08625 bc5b7fc9a599fdc4a902b515a977f2a4 128 Pfam PF01022 Bacterial regulatory protein, arsR family 51 96 1.0E-9 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A0127_08625 bc5b7fc9a599fdc4a902b515a977f2a4 128 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 46 61 2.9E-16 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A0127_08625 bc5b7fc9a599fdc4a902b515a977f2a4 128 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 65 76 2.9E-16 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A0127_08625 bc5b7fc9a599fdc4a902b515a977f2a4 128 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 78 93 2.9E-16 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A0127_08625 bc5b7fc9a599fdc4a902b515a977f2a4 128 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 93 108 2.9E-16 T 23-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 A0127_07720 7d768394277610b23196d40e8ee634aa 51 Gene3D G3DSA:2.20.28.70 1 48 2.6E-18 T 23-10-2018 IPR038587 Ribosomal protein L40e superfamily Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 A0127_07720 7d768394277610b23196d40e8ee634aa 51 Hamap MF_00788 50S ribosomal protein L40e [rpl40e]. 2 47 19.187 T 23-10-2018 IPR023657 Ribosomal protein L40e, archaeal GO:0003735|GO:0005840|GO:0006412 A0127_07720 7d768394277610b23196d40e8ee634aa 51 SMART SM01377 1 46 7.2E-9 T 23-10-2018 IPR001975 Ribosomal protein L40e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 A0127_07720 7d768394277610b23196d40e8ee634aa 51 SUPERFAMILY SSF57829 2 46 8.79E-16 T 23-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 A0127_04635 daea5275cce95b8a45c69943e2081dbd 258 SUPERFAMILY SSF109604 13 170 4.4E-9 T 23-10-2018 A0127_04635 daea5275cce95b8a45c69943e2081dbd 258 SMART SM00471 48 181 0.0034 T 23-10-2018 IPR003607 HD/PDEase domain A0127_04635 daea5275cce95b8a45c69943e2081dbd 258 Gene3D G3DSA:1.10.3210.10 12 202 1.4E-7 T 23-10-2018 A0127_04540 9264216ef90168348602d1de74a79966 130 Gene3D G3DSA:1.10.10.10 1 51 9.6E-7 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A0127_04540 9264216ef90168348602d1de74a79966 130 SUPERFAMILY SSF88659 9 48 5.79E-8 T 23-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like A0127_02915 ca78e3b2b0085d3a010d88abd1304ea1 121 Gene3D G3DSA:1.20.120.330 1 113 3.1E-23 T 23-10-2018 A0127_02915 ca78e3b2b0085d3a010d88abd1304ea1 121 SUPERFAMILY SSF81593 1 112 1.84E-26 T 23-10-2018 A0127_02915 ca78e3b2b0085d3a010d88abd1304ea1 121 SMART SM00748 1 105 3.7E-29 T 23-10-2018 IPR007842 HEPN domain A0127_02915 ca78e3b2b0085d3a010d88abd1304ea1 121 Pfam PF05168 HEPN domain 2 110 1.4E-25 T 23-10-2018 IPR007842 HEPN domain A0127_07420 aedb9799ddc53fe49834395a7c014135 299 Gene3D G3DSA:3.30.930.10 1 299 1.6E-75 T 23-10-2018 A0127_07420 aedb9799ddc53fe49834395a7c014135 299 SUPERFAMILY SSF55681 8 295 3.32E-55 T 23-10-2018 A0127_07420 aedb9799ddc53fe49834395a7c014135 299 Pfam PF00152 tRNA synthetases class II (D, K and N) 4 292 1.0E-41 T 23-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 A0127_01380 26f144105a0ecd0d79479a9d1b9b6825 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 6.1E-26 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A0127_01380 26f144105a0ecd0d79479a9d1b9b6825 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 6.1E-26 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A0127_01380 26f144105a0ecd0d79479a9d1b9b6825 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 222 242 6.1E-26 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A0127_01380 26f144105a0ecd0d79479a9d1b9b6825 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 6.1E-26 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A0127_01380 26f144105a0ecd0d79479a9d1b9b6825 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 6.1E-26 T 23-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR A0127_01380 26f144105a0ecd0d79479a9d1b9b6825 263 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 18 257 3.4E-49 T 23-10-2018 A0127_01380 26f144105a0ecd0d79479a9d1b9b6825 263 SUPERFAMILY SSF51735 8 258 3.21E-66 T 23-10-2018 IPR036291 NAD(P)-binding domain superfamily A0127_01380 26f144105a0ecd0d79479a9d1b9b6825 263 Gene3D G3DSA:3.40.50.720 2 262 3.7E-64 T 23-10-2018 A0127_03460 ace9913d329fb81fe692e3a35994ec3f 108 Pfam PF01922 SRP19 protein 4 81 1.2E-12 T 23-10-2018 IPR002778 Signal recognition particle, SRP19 subunit GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 A0127_03460 ace9913d329fb81fe692e3a35994ec3f 108 Gene3D G3DSA:3.30.56.30 1 105 3.6E-32 T 23-10-2018 IPR036521 Signal recognition particle, subunit SRP19-like superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 A0127_03460 ace9913d329fb81fe692e3a35994ec3f 108 SUPERFAMILY SSF69695 2 106 1.83E-22 T 23-10-2018 IPR036521 Signal recognition particle, subunit SRP19-like superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 A0127_03460 ace9913d329fb81fe692e3a35994ec3f 108 Hamap MF_00305 Signal recognition particle 19 kDa protein [srp19]. 4 93 22.246 T 23-10-2018 IPR022938 Signal recognition particle, SRP19 subunit, archaeal-type A0127_04520 e9467edb157327b4c908b4c909d0a415 264 Pfam PF00795 Carbon-nitrogen hydrolase 2 244 2.9E-59 T 23-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 A0127_04520 e9467edb157327b4c908b4c909d0a415 264 Gene3D G3DSA:3.60.110.10 1 263 4.9E-104 T 23-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily A0127_04520 e9467edb157327b4c908b4c909d0a415 264 SUPERFAMILY SSF56317 1 264 7.59E-76 T 23-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily A0127_06950 d80ac51db1104ab69d9daebc99322c04 398 SUPERFAMILY SSF103473 18 397 8.11E-61 T 23-10-2018 IPR036259 MFS transporter superfamily A0127_06950 d80ac51db1104ab69d9daebc99322c04 398 Gene3D G3DSA:1.20.1250.20 220 398 1.7E-23 T 23-10-2018 A0127_06950 d80ac51db1104ab69d9daebc99322c04 398 Gene3D G3DSA:1.20.1250.20 17 211 2.6E-26 T 23-10-2018 A0127_06950 d80ac51db1104ab69d9daebc99322c04 398 Pfam PF07690 Major Facilitator Superfamily 24 265 2.2E-25 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A0127_08280 507983d139605b56ea323528ebb6fcf5 226 Gene3D G3DSA:1.20.1260.10 60 226 1.0E-67 T 23-10-2018 IPR012347 Ferritin-like A0127_08280 507983d139605b56ea323528ebb6fcf5 226 Pfam PF09968 Uncharacterized protein domain (DUF2202) 65 223 2.5E-64 T 23-10-2018 IPR019243 Domain of unknown function DUF2202 A0127_08280 507983d139605b56ea323528ebb6fcf5 226 SUPERFAMILY SSF47240 64 199 9.41E-11 T 23-10-2018 IPR009078 Ferritin-like superfamily A0127_08845 78e3dc88372eed160706e3046e9926b7 177 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 39 155 4.6E-31 T 23-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A0127_08845 78e3dc88372eed160706e3046e9926b7 177 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 89 130 2.0E-17 T 23-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A0127_08845 78e3dc88372eed160706e3046e9926b7 177 Gene3D G3DSA:3.30.460.80 3 133 1.6E-26 T 23-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A0127_08845 78e3dc88372eed160706e3046e9926b7 177 SUPERFAMILY SSF143243 23 163 9.15E-36 T 23-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A0127_00450 cfa3fe8dc6e35f7f38523bf82d0e83eb 263 SUPERFAMILY SSF48150 16 253 1.1E-82 T 23-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 A0127_00450 cfa3fe8dc6e35f7f38523bf82d0e83eb 263 PIRSF PIRSF008955 12 263 2.0E-108 T 23-10-2018 IPR016544 N-glycosylase/DNA lyase GO:0000702|GO:0003906|GO:0006284 A0127_00450 cfa3fe8dc6e35f7f38523bf82d0e83eb 263 Hamap MF_01168 N-glycosylase/DNA lyase. 20 257 41.258 T 23-10-2018 IPR016544 N-glycosylase/DNA lyase GO:0000702|GO:0003906|GO:0006284 A0127_00450 cfa3fe8dc6e35f7f38523bf82d0e83eb 263 Pfam PF09171 N-glycosylase/DNA lyase 23 245 9.3E-87 T 23-10-2018 IPR015254 N-glycosylase/DNA lyase-like GO:0003906|GO:0016799 A0127_00450 cfa3fe8dc6e35f7f38523bf82d0e83eb 263 Gene3D G3DSA:1.10.340.30 41 188 1.3E-82 T 23-10-2018 A0127_00450 cfa3fe8dc6e35f7f38523bf82d0e83eb 263 Gene3D G3DSA:1.10.1670.10 21 253 1.3E-82 T 23-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 A0127_02780 0f4b37fc235e456bfc2a7fcc21422158 583 Gene3D G3DSA:3.60.10.10 358 583 7.6E-34 T 23-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily A0127_02780 0f4b37fc235e456bfc2a7fcc21422158 583 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 376 573 3.5E-7 T 23-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase A0127_02780 0f4b37fc235e456bfc2a7fcc21422158 583 SUPERFAMILY SSF56219 353 581 5.5E-32 T 23-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily A0127_10020 83987464192734bb3bde2da133b80b06 432 Hamap MF_01908 Cyclic 2,3-diphosphoglycerate synthetase [cpgS]. 1 432 51.984 T 23-10-2018 IPR016557 Cyclic 2, 3-diphospoglycerate synthetase GO:0005737|GO:0006094|GO:0036356 A0127_10020 83987464192734bb3bde2da133b80b06 432 PIRSF PIRSF009445 1 432 9.4E-210 T 23-10-2018 IPR016557 Cyclic 2, 3-diphospoglycerate synthetase GO:0005737|GO:0006094|GO:0036356 A0127_10020 83987464192734bb3bde2da133b80b06 432 Gene3D G3DSA:3.40.50.300 197 317 2.4E-5 T 23-10-2018 A0127_01400 e72b7b2ea0d371ed00fb416f782b6883 446 Pfam PF01458 Uncharacterized protein family (UPF0051) 195 418 7.4E-55 T 23-10-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 A0127_01400 e72b7b2ea0d371ed00fb416f782b6883 446 TIGRFAM TIGR01980 sufB: FeS assembly protein SufB 8 438 4.5E-104 T 23-10-2018 IPR010231 SUF system FeS cluster assembly, SufB GO:0016226 A0127_01400 e72b7b2ea0d371ed00fb416f782b6883 446 SUPERFAMILY SSF101960 16 442 3.4E-103 T 23-10-2018 IPR037284 SUF system FeS cluster assembly, SufBD superfamily A0127_05360 f534e47689f4f99a722182ced7cd4f62 143 SUPERFAMILY SSF54862 27 106 4.86E-22 T 23-10-2018 A0127_05360 f534e47689f4f99a722182ced7cd4f62 143 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 77 88 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A0127_05360 f534e47689f4f99a722182ced7cd4f62 143 Pfam PF13187 4Fe-4S dicluster domain 45 91 2.7E-11 T 23-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain A0127_05360 f534e47689f4f99a722182ced7cd4f62 143 Gene3D G3DSA:3.30.70.3270 23 143 6.3E-22 T 23-10-2018 A0127_05360 f534e47689f4f99a722182ced7cd4f62 143 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 46 57 - T 23-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site A0127_06115 b9592a476c7a9ebb3376d699386570b4 443 SUPERFAMILY SSF161098 225 426 1.24E-6 T 23-10-2018 IPR035906 MetI-like superfamily A0127_08860 43a1bfe62268348c8d4d182cf0bb9c45 200 Pfam PF06195 Protein of unknown function (DUF996) 41 171 1.2E-25 T 23-10-2018 IPR010397 Protein of unknown function DUF996 A0127_02660 1428db4ad52b1b51e9e44280e3e496b2 237 Gene3D G3DSA:3.20.20.410 1 237 5.1E-42 T 23-10-2018 IPR036520 UPF0759 superfamily A0127_02660 1428db4ad52b1b51e9e44280e3e496b2 237 SUPERFAMILY SSF117396 1 237 1.44E-47 T 23-10-2018 IPR036520 UPF0759 superfamily A0127_02660 1428db4ad52b1b51e9e44280e3e496b2 237 Pfam PF01904 Protein of unknown function DUF72 15 234 8.4E-39 T 23-10-2018 IPR002763 Protein of unknown function DUF72 A0127_04315 0d0345271038f5d38da02c1f97ae9a28 337 Pfam PF01032 FecCD transport family 13 329 5.4E-83 T 23-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 A0127_04315 0d0345271038f5d38da02c1f97ae9a28 337 Gene3D G3DSA:1.10.3470.10 1 336 2.8E-91 T 23-10-2018 IPR037294 ABC transporter, BtuC-like A0127_04315 0d0345271038f5d38da02c1f97ae9a28 337 SUPERFAMILY SSF81345 4 329 4.05E-74 T 23-10-2018 IPR037294 ABC transporter, BtuC-like A0127_01860 5e415f8982f8778dc2ab64b676a8b65b 485 Gene3D G3DSA:3.40.190.10 155 274 3.3E-36 T 23-10-2018 A0127_01860 5e415f8982f8778dc2ab64b676a8b65b 485 SUPERFAMILY SSF53850 88 327 5.62E-42 T 23-10-2018 A0127_01860 5e415f8982f8778dc2ab64b676a8b65b 485 Pfam PF13416 Bacterial extracellular solute-binding protein 92 323 3.2E-21 T 23-10-2018 IPR006059 Bacterial extracellular solute-binding protein A0127_01860 5e415f8982f8778dc2ab64b676a8b65b 485 Gene3D G3DSA:3.40.190.10 90 317 3.3E-36 T 23-10-2018 A0127_09195 523c8032ccc64ea15067b8e81831c82b 710 Pfam PF04471 Restriction endonuclease 18 123 4.1E-11 T 23-10-2018 IPR007560 Restriction endonuclease type IV, Mrr GO:0003677|GO:0004519|GO:0009307 A0127_09195 523c8032ccc64ea15067b8e81831c82b 710 SUPERFAMILY SSF52980 19 129 3.0E-5 T 23-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 A0127_09175 2d94f41b42fbc8f57b9e4d7ef645eb3f 255 Pfam PF12679 ABC-2 family transporter protein 2 193 1.4E-14 T 23-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 A0127_06615 abd0e13a1348a47eff723d7a109e75da 415 Pfam PF00884 Sulfatase 4 312 2.0E-20 T 23-10-2018 IPR000917 Sulfatase, N-terminal GO:0008484 A0127_06615 abd0e13a1348a47eff723d7a109e75da 415 SUPERFAMILY SSF53649 2 309 2.62E-35 T 23-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 A0127_00620 36e2936d6ca8040d9b695a079edf8f8c 277 ProDom PD039347 PF1398 MJ0538 PH1392 4 256 3.0E-133 T 23-10-2018 IPR020292 Uncharacterised protein family MJ0538 A0127_06895 6cd1ad5001232b8b55cdd11db00168d6 224 Pfam PF04021 Class III signal peptide 2 27 3.7E-8 T 23-10-2018 IPR007166 Class III signal peptide motif A0127_09380 6903625abb796d406d5b9fc6200c8949 94 Pfam PF04066 Multiple resistance and pH regulation protein F (MrpF / PhaF) 36 87 7.5E-9 T 23-10-2018 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 A0127_01525 7eb9e78b1b8240222860bde8d4ab0ec3 193 SMART SM01022 12 113 2.8E-20 T 23-10-2018 IPR007374 ASCH domain A0127_01525 7eb9e78b1b8240222860bde8d4ab0ec3 193 SUPERFAMILY SSF88697 9 112 1.49E-20 T 23-10-2018 IPR015947 PUA-like superfamily A0127_01525 7eb9e78b1b8240222860bde8d4ab0ec3 193 Pfam PF04266 ASCH domain 15 113 1.8E-21 T 23-10-2018 IPR007374 ASCH domain A0127_00730 4ce16c0af3710f1f749fe654691daedf 315 PRINTS PR00102 Ornithine carbamoyltransferase signature 124 138 1.8E-30 T 23-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 A0127_00730 4ce16c0af3710f1f749fe654691daedf 315 PRINTS PR00102 Ornithine carbamoyltransferase signature 84 97 1.8E-30 T 23-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 A0127_00730 4ce16c0af3710f1f749fe654691daedf 315 PRINTS PR00102 Ornithine carbamoyltransferase signature 227 237 1.8E-30 T 23-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 A0127_00730 4ce16c0af3710f1f749fe654691daedf 315 PRINTS PR00102 Ornithine carbamoyltransferase signature 51 65 1.8E-30 T 23-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 A0127_00730 4ce16c0af3710f1f749fe654691daedf 315 PRINTS PR00102 Ornithine carbamoyltransferase signature 289 300 1.8E-30 T 23-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 A0127_00730 4ce16c0af3710f1f749fe654691daedf 315 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 8 148 6.6E-51 T 23-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 A0127_00730 4ce16c0af3710f1f749fe654691daedf 315 Gene3D G3DSA:3.40.50.1370 138 297 7.8E-139 T 23-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 A0127_00730 4ce16c0af3710f1f749fe654691daedf 315 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 154 308 2.3E-66 T 23-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 A0127_00730 4ce16c0af3710f1f749fe654691daedf 315 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 53 60 - T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A0127_00730 4ce16c0af3710f1f749fe654691daedf 315 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 7 311 85.839 T 23-10-2018 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 A0127_00730 4ce16c0af3710f1f749fe654691daedf 315 SUPERFAMILY SSF53671 4 313 1.7E-116 T 23-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 A0127_00730 4ce16c0af3710f1f749fe654691daedf 315 Gene3D G3DSA:3.40.50.1370 10 307 7.8E-139 T 23-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 A0127_00730 4ce16c0af3710f1f749fe654691daedf 315 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 275 298 1.8E-29 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A0127_00730 4ce16c0af3710f1f749fe654691daedf 315 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 135 146 1.8E-29 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A0127_00730 4ce16c0af3710f1f749fe654691daedf 315 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 53 72 1.8E-29 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A0127_00730 4ce16c0af3710f1f749fe654691daedf 315 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 263 272 1.8E-29 T 23-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 A0127_00730 4ce16c0af3710f1f749fe654691daedf 315 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 8 310 1.3E-146 T 23-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 A0127_05310 4330e6b9e8739e8a32484c9461477a52 88 Pfam PF13244 Domain of unknown function (DUF4040) 17 82 5.2E-17 T 23-10-2018 IPR025383 Domain of unknown function DUF4040 A0127_06650 915c8817e5b16c0f3fce74df25283148 247 Pfam PF01925 Sulfite exporter TauE/SafE 6 239 4.3E-44 T 23-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 A0127_09155 8234019198b2c3641309c26db43c27ab 161 Gene3D G3DSA:2.60.40.790 2 160 7.4E-32 T 23-10-2018 IPR008978 HSP20-like chaperone A0127_09155 8234019198b2c3641309c26db43c27ab 161 Pfam PF00011 Hsp20/alpha crystallin family 57 153 5.2E-19 T 23-10-2018 IPR002068 Alpha crystallin/Hsp20 domain A0127_09155 8234019198b2c3641309c26db43c27ab 161 SUPERFAMILY SSF49764 38 153 6.15E-32 T 23-10-2018 IPR008978 HSP20-like chaperone A0127_04675 ddeb64ae3b86d8422bf0c5225d446411 351 Pfam PF16575 mRNA cleavage and polyadenylation factor CLP1 P-loop 34 208 1.2E-35 T 23-10-2018 IPR032319 Polyribonucleotide 5'-hydroxyl-kinase Clp1, P-loop domain A0127_04675 ddeb64ae3b86d8422bf0c5225d446411 351 SUPERFAMILY SSF52540 10 146 4.71E-13 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_04675 ddeb64ae3b86d8422bf0c5225d446411 351 Gene3D G3DSA:3.40.50.300 10 213 6.8E-24 T 23-10-2018 A0127_02450 fa6a3d4fdc81ca8b36e3ed84df9dd030 202 Pfam PF00881 Nitroreductase family 7 181 5.0E-35 T 23-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 A0127_02450 fa6a3d4fdc81ca8b36e3ed84df9dd030 202 SUPERFAMILY SSF55469 1 200 5.63E-45 T 23-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A0127_02450 fa6a3d4fdc81ca8b36e3ed84df9dd030 202 Gene3D G3DSA:3.40.109.10 1 201 6.4E-49 T 23-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 A0127_00100 5b6ecfa71f58d57cf2cdcc60249ed637 146 Pfam PF02996 Prefoldin subunit 18 137 3.2E-26 T 23-10-2018 IPR004127 Prefoldin alpha-like A0127_00100 5b6ecfa71f58d57cf2cdcc60249ed637 146 Gene3D G3DSA:1.10.287.370 1 146 1.7E-44 T 23-10-2018 IPR009053 Prefoldin A0127_00100 5b6ecfa71f58d57cf2cdcc60249ed637 146 TIGRFAM TIGR00293 TIGR00293: prefoldin, alpha subunit 8 137 2.1E-36 T 23-10-2018 IPR011599 Prefoldin alpha subunit, archaea-type GO:0006457|GO:0016272|GO:0051082 Reactome: R-HSA-389957 A0127_00100 5b6ecfa71f58d57cf2cdcc60249ed637 146 SUPERFAMILY SSF46579 7 139 3.31E-32 T 23-10-2018 A0127_00100 5b6ecfa71f58d57cf2cdcc60249ed637 146 Hamap MF_00308 Prefoldin subunit alpha [pfdA]. 3 137 15.796 T 23-10-2018 IPR011599 Prefoldin alpha subunit, archaea-type GO:0006457|GO:0016272|GO:0051082 Reactome: R-HSA-389957 A0127_05060 e1febd18014512bbef4ebd98f7bd3011 246 PIRSF PIRSF019322 2 245 1.1E-89 T 23-10-2018 IPR016757 Uncharacterised conserved protein UCP019322 A0127_05060 e1febd18014512bbef4ebd98f7bd3011 246 Pfam PF09883 Uncharacterized protein conserved in archaea (DUF2110) 6 235 4.5E-74 T 23-10-2018 IPR016757 Uncharacterised conserved protein UCP019322 A0127_05540 313c40ee7aa917979e5da2296e756b71 175 Gene3D G3DSA:3.30.930.10 2 173 2.5E-60 T 23-10-2018 A0127_05540 313c40ee7aa917979e5da2296e756b71 175 Pfam PF11447 Protein of unknown function (DUF3201) 12 162 1.7E-76 T 23-10-2018 IPR024505 Protein of unknown function DUF3201 A0127_05540 313c40ee7aa917979e5da2296e756b71 175 SUPERFAMILY SSF142913 6 173 1.7E-57 T 23-10-2018 A0127_05935 03054eaccb1b2b5197ddff1d46b9dc27 159 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 3 148 9.0E-23 T 23-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain A0127_05935 03054eaccb1b2b5197ddff1d46b9dc27 159 Gene3D G3DSA:3.10.50.80 2 158 2.4E-54 T 23-10-2018 A0127_05935 03054eaccb1b2b5197ddff1d46b9dc27 159 SUPERFAMILY SSF54534 2 151 9.23E-50 T 23-10-2018 A0127_04640 6a80e5222b2723e154e54f6c3096b0b3 140 Pfam PF04900 Fcf1 35 132 9.3E-7 T 23-10-2018 IPR006984 rRNA-processing protein Fcf1/Utp23 GO:0032040 A0127_04640 6a80e5222b2723e154e54f6c3096b0b3 140 Gene3D G3DSA:3.40.50.1010 9 138 3.6E-29 T 23-10-2018 A0127_04640 6a80e5222b2723e154e54f6c3096b0b3 140 SUPERFAMILY SSF88723 9 132 2.85E-23 T 23-10-2018 IPR029060 PIN-like domain superfamily A0127_04640 6a80e5222b2723e154e54f6c3096b0b3 140 SMART SM00670 9 115 8.2E-6 T 23-10-2018 IPR002716 PIN domain A0127_03455 8ae41ced3ff83b34ea4b8b4261fae035 207 Gene3D G3DSA:3.40.50.11570 8 204 1.8E-15 T 23-10-2018 A0127_03455 8ae41ced3ff83b34ea4b8b4261fae035 207 Pfam PF03192 Pyrococcus protein of unknown function, DUF257 14 196 3.4E-14 T 23-10-2018 IPR005489 Protein of unknown function DUF257 A0127_03125 35ddc8f34be19b4b29b42d09aa9ad8de 391 Pfam PF04123 Domain of unknown function (DUF373) 5 353 1.3E-100 T 23-10-2018 IPR007254 Protein of unknown function DUF373 A0127_10215 83037e50e70f7ef9199b3b23feba812f 296 Pfam PF16147 Domain of unknown function (DUF4855) 109 277 4.5E-8 T 23-10-2018 IPR032329 Protein of unknown function DUF4855 A0127_09285 02521b1eba45dbb6807d0539e6f462b1 281 Gene3D G3DSA:3.40.50.970 84 257 5.7E-29 T 23-10-2018 A0127_09285 02521b1eba45dbb6807d0539e6f462b1 281 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 56 202 1.9E-35 T 23-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 A0127_09285 02521b1eba45dbb6807d0539e6f462b1 281 SUPERFAMILY SSF52518 19 273 1.71E-74 T 23-10-2018 IPR029061 Thiamin diphosphate-binding fold A0127_07600 d46d9e7b06d7ae68311c9003d8e1953f 174 Pfam PF01956 Integral membrane protein DUF106 11 173 3.0E-29 T 23-10-2018 IPR002809 Integral membrane protein EMC3/TMCO1-like GO:0016020 A0127_07600 d46d9e7b06d7ae68311c9003d8e1953f 174 SMART SM01415 10 173 5.5E-21 T 23-10-2018 IPR002809 Integral membrane protein EMC3/TMCO1-like GO:0016020 A0127_03945 205c013cd1d929219cadb318d48b20c8 119 SUPERFAMILY SSF50447 1 72 4.24E-17 T 23-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily A0127_03945 205c013cd1d929219cadb318d48b20c8 119 Gene3D G3DSA:2.40.10.230 1 75 5.7E-25 T 23-10-2018 IPR038664 H/ACA RNP complex subunit Gar1/Naf1, Cbf5-binding domain A0127_03945 205c013cd1d929219cadb318d48b20c8 119 ProDom PD064583 RNA-BINDING GAR1 COMPONENT RNP SNORNP HOMOLOG NUCLEOLAR PROCESSING RRNA VNG1366H 1 71 3.0E-34 T 23-10-2018 IPR020321 H/ACA ribonucleoprotein complex, subunit Gar1, archaea GO:0001522|GO:0042254 A0127_03945 205c013cd1d929219cadb318d48b20c8 119 Pfam PF04410 Gar1/Naf1 RNA binding region 2 58 1.1E-8 T 23-10-2018 IPR007504 H/ACA ribonucleoprotein complex, subunit Gar1/Naf1 GO:0001522|GO:0042254 A0127_05300 55d39f0795ee0711785b0f45199419be 85 Pfam PF04066 Multiple resistance and pH regulation protein F (MrpF / PhaF) 29 80 1.7E-21 T 23-10-2018 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 A0127_09005 f9880bb782bdd25bfe7b6d691a832a2a 378 Pfam PF05763 Protein of unknown function (DUF835) 231 368 4.3E-35 T 23-10-2018 IPR008553 Domain of unknown function DUF835 A0127_06120 45d87deb395b3de79a7fa98c7b044652 337 SUPERFAMILY SSF161098 96 286 4.45E-6 T 23-10-2018 IPR035906 MetI-like superfamily A0127_06120 45d87deb395b3de79a7fa98c7b044652 337 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 114 331 1.2E-16 T 23-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 A0127_06120 45d87deb395b3de79a7fa98c7b044652 337 Gene3D G3DSA:1.10.3720.10 94 332 8.3E-11 T 23-10-2018 IPR035906 MetI-like superfamily A0127_00125 336ac921d7f4476e82a8b9ee67ced533 259 Gene3D G3DSA:3.40.50.1820 2 255 5.8E-67 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold A0127_00125 336ac921d7f4476e82a8b9ee67ced533 259 Pfam PF12146 Serine aminopeptidase, S33 11 240 4.8E-70 T 23-10-2018 IPR022742 Serine aminopeptidase, S33 A0127_00125 336ac921d7f4476e82a8b9ee67ced533 259 SUPERFAMILY SSF53474 7 253 4.39E-49 T 23-10-2018 IPR029058 Alpha/Beta hydrolase fold A0127_00125 336ac921d7f4476e82a8b9ee67ced533 259 PRINTS PR00111 Alpha/beta hydrolase fold signature 40 55 4.6E-6 T 23-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A0127_00125 336ac921d7f4476e82a8b9ee67ced533 259 PRINTS PR00111 Alpha/beta hydrolase fold signature 97 110 4.6E-6 T 23-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A0127_00125 336ac921d7f4476e82a8b9ee67ced533 259 PRINTS PR00111 Alpha/beta hydrolase fold signature 83 96 4.6E-6 T 23-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A0127_00125 336ac921d7f4476e82a8b9ee67ced533 259 PRINTS PR00111 Alpha/beta hydrolase fold signature 195 209 4.6E-6 T 23-10-2018 IPR000073 Alpha/beta hydrolase fold-1 A0127_06465 23a2400018c3d2ce15134c55e9d09624 329 Pfam PF07760 Protein of unknown function (DUF1616) 11 312 1.4E-91 T 23-10-2018 IPR011674 Domain of unknown function DUF1616 A0127_06465 23a2400018c3d2ce15134c55e9d09624 329 PIRSF PIRSF018671 1 329 6.5E-120 T 23-10-2018 IPR014495 Uncharacterised conserved protein UCP018671 A0127_08830 905cf4b25e0a13d0d62d02bc09345078 616 Pfam PF00361 Proton-conducting membrane transporter 121 419 8.3E-54 T 23-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A0127_01025 56f3b4e23ebb145b9fab6f2215471dba 151 Pfam PF10015 Uncharacterized protein conserved in archaea (DUF2258) 3 73 1.6E-24 T 23-10-2018 IPR017140 Uncharacterised conserved protein UCP037214 A0127_05215 839db4e2baab90b943d12fcdd842a38d 306 Pfam PF12679 ABC-2 family transporter protein 3 305 1.9E-58 T 23-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 A0127_01820 b44b9f891bdeae3f3d09fd7c7090b3f7 455 SUPERFAMILY SSF111283 2 450 5.36E-97 T 23-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 A0127_01820 b44b9f891bdeae3f3d09fd7c7090b3f7 455 PIRSF PIRSF004919 1 455 1.9E-158 T 23-10-2018 IPR025502 TldD A0127_01820 b44b9f891bdeae3f3d09fd7c7090b3f7 455 Pfam PF01523 Putative modulator of DNA gyrase 19 310 1.2E-45 T 23-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 A0127_01820 b44b9f891bdeae3f3d09fd7c7090b3f7 455 Gene3D G3DSA:3.30.2290.10 1 212 2.9E-16 T 23-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal A0127_03055 163e3618fbab559fb757737006961454 417 Pfam PF00155 Aminotransferase class I and II 68 405 1.7E-37 T 23-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A0127_03055 163e3618fbab559fb757737006961454 417 Gene3D G3DSA:3.40.640.10 79 304 6.3E-164 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A0127_03055 163e3618fbab559fb757737006961454 417 SUPERFAMILY SSF53383 15 411 3.94E-121 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A0127_03055 163e3618fbab559fb757737006961454 417 Gene3D G3DSA:3.90.1150.10 34 409 6.3E-164 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A0127_00020 3de20177a3e35b38110e45f7e7ba51da 142 Pfam PF01986 Domain of unknown function DUF123 25 110 1.4E-21 T 23-10-2018 IPR002837 Protein of unknown function DUF123 A0127_00020 3de20177a3e35b38110e45f7e7ba51da 142 SMART SM00465 18 113 2.2E-7 T 23-10-2018 IPR000305 GIY-YIG endonuclease A0127_02130 3d6a63b28a6f7a8c055cc7026bd771e5 135 Pfam PF04039 Domain related to MnhB subunit of Na+/H+ antiporter 6 122 7.0E-26 T 23-10-2018 IPR007182 Na+/H+ antiporter MnhB subunit-related protein A0127_08095 dc01962657b04659adf9b21265bf2089 464 Pfam PF13662 Toprim domain 199 282 4.0E-13 T 23-10-2018 IPR006171 TOPRIM domain A0127_08095 dc01962657b04659adf9b21265bf2089 464 Gene3D G3DSA:3.40.1360.10 196 291 8.8E-13 T 23-10-2018 A0127_08095 dc01962657b04659adf9b21265bf2089 464 SUPERFAMILY SSF56731 197 295 9.68E-11 T 23-10-2018 A0127_08095 dc01962657b04659adf9b21265bf2089 464 Hamap MF_00007 DNA primase DnaG [dnaG]. 34 463 36.52 T 23-10-2018 IPR020607 DNA primase DnaG, archaea GO:0000178|GO:0003896|GO:0008143 A0127_08095 dc01962657b04659adf9b21265bf2089 464 SMART SM00493 198 267 1.3E-12 T 23-10-2018 IPR006171 TOPRIM domain A0127_03765 e83f88e847ef898c0d71f2fcce423e06 217 SUPERFAMILY SSF56784 1 215 1.73E-40 T 23-10-2018 IPR036412 HAD-like superfamily A0127_03765 e83f88e847ef898c0d71f2fcce423e06 217 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 104 184 1.1E-8 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A0127_03765 e83f88e847ef898c0d71f2fcce423e06 217 Gene3D G3DSA:1.10.150.240 15 89 5.0E-31 T 23-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 A0127_03765 e83f88e847ef898c0d71f2fcce423e06 217 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 190 1.8E-26 T 23-10-2018 A0127_03765 e83f88e847ef898c0d71f2fcce423e06 217 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 97 188 5.9E-8 T 23-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 A0127_03765 e83f88e847ef898c0d71f2fcce423e06 217 Gene3D G3DSA:3.40.50.1000 4 203 5.0E-31 T 23-10-2018 IPR023214 HAD superfamily A0127_00275 8756007462a35b565acaa35f98c20cc3 455 PIRSF PIRSF006603 1 455 5.5E-107 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A0127_00275 8756007462a35b565acaa35f98c20cc3 455 Pfam PF01554 MatE 240 406 4.9E-37 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A0127_00275 8756007462a35b565acaa35f98c20cc3 455 Pfam PF01554 MatE 16 176 4.3E-38 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A0127_00275 8756007462a35b565acaa35f98c20cc3 455 TIGRFAM TIGR00797 matE: MATE efflux family protein 16 427 1.4E-125 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A0127_05235 b58f12722e9818bbdc04676ccb5de92d 403 Pfam PF01384 Phosphate transporter family 19 392 8.3E-111 T 23-10-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 A0127_04920 a4057d6ffe45c8913e52b6b9164f3934 235 Pfam PF00588 SpoU rRNA Methylase family 2 150 6.2E-34 T 23-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 A0127_04920 a4057d6ffe45c8913e52b6b9164f3934 235 SUPERFAMILY SSF75217 3 175 1.05E-32 T 23-10-2018 IPR029028 Alpha/beta knot methyltransferases A0127_04920 a4057d6ffe45c8913e52b6b9164f3934 235 Gene3D G3DSA:3.40.1280.10 1 156 9.0E-50 T 23-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal A0127_04920 a4057d6ffe45c8913e52b6b9164f3934 235 PIRSF PIRSF004808 1 235 3.0E-76 T 23-10-2018 IPR004384 RNA methyltransferase TrmJ/LasT GO:0006396|GO:0008173 A0127_04920 a4057d6ffe45c8913e52b6b9164f3934 235 TIGRFAM TIGR00050 rRNA_methyl_1: RNA methyltransferase, TrmH family, group 1 1 228 2.7E-65 T 23-10-2018 IPR004384 RNA methyltransferase TrmJ/LasT GO:0006396|GO:0008173 A0127_05185 6bdc1f2b00525b0e419098ec6ef5bcdb 990 Gene3D G3DSA:2.40.50.140 886 989 3.9E-6 T 23-10-2018 A0127_05185 6bdc1f2b00525b0e419098ec6ef5bcdb 990 SUPERFAMILY SSF50249 911 987 6.0E-7 T 23-10-2018 IPR012340 Nucleic acid-binding, OB-fold A0127_03050 6dd884b5eaf4d1df76041c4f3d993c22 283 Pfam PF07722 Peptidase C26 14 218 4.7E-52 T 23-10-2018 IPR011697 Peptidase C26 GO:0016787 Reactome: R-HSA-6798695 A0127_03050 6dd884b5eaf4d1df76041c4f3d993c22 283 SUPERFAMILY SSF52317 2 240 1.02E-34 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A0127_03050 6dd884b5eaf4d1df76041c4f3d993c22 283 Gene3D G3DSA:3.40.50.880 1 246 2.9E-63 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A0127_02425 2ff2f566c5fe6fa41c38ad9f580f3757 381 Pfam PF05559 Protein of unknown function (DUF763) 4 335 5.2E-122 T 23-10-2018 IPR008482 Protein of unknown function DUF763 A0127_05380 9064ae5cfb1487c7d5169681c1cc50db 402 SUPERFAMILY SSF52540 55 312 2.38E-23 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_02155 592201ae5023bbb47f233a37693ef2b2 201 PIRSF PIRSF019239 29 201 5.7E-59 T 23-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 A0127_02155 592201ae5023bbb47f233a37693ef2b2 201 Pfam PF01899 Na+/H+ ion antiporter subunit 40 199 7.0E-41 T 23-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 A0127_02125 ad2e085eb68280d43c19a9dc9fa32ad0 96 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 7 92 4.2E-17 T 23-10-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like A0127_01965 65ca6ffbb390523fbddfc38bdef6e29e 389 Gene3D G3DSA:3.90.1150.10 27 378 2.2E-154 T 23-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 A0127_01965 65ca6ffbb390523fbddfc38bdef6e29e 389 Gene3D G3DSA:3.40.640.10 58 280 2.2E-154 T 23-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 A0127_01965 65ca6ffbb390523fbddfc38bdef6e29e 389 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 230 243 - T 23-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 A0127_01965 65ca6ffbb390523fbddfc38bdef6e29e 389 Pfam PF00155 Aminotransferase class I and II 27 378 1.4E-79 T 23-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 A0127_01965 65ca6ffbb390523fbddfc38bdef6e29e 389 SUPERFAMILY SSF53383 2 385 2.39E-126 T 23-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase A0127_09080 e5f93170c9c10aeccb6875543b5e8638 254 Gene3D G3DSA:3.40.50.300 5 242 2.6E-58 T 23-10-2018 A0127_04215 baf9f091111dc117f0d828dbf1d802f1 218 Pfam PF07758 Protein of unknown function (DUF1614) 40 217 2.3E-54 T 23-10-2018 IPR011672 Protein of unknown function DUF1614 A0127_07330 cb8a063bac9933a842e55d5f3513887f 481 PIRSF PIRSF008315 1 476 5.3E-190 T 23-10-2018 IPR016539 Uncharacterised conserved protein UCP008315 A0127_00865 2a985e55e36bdc076a1cf5a716416585 183 Pfam PF06197 Protein of unknown function (DUF998) 12 176 6.2E-23 T 23-10-2018 IPR009339 Protein of unknown function DUF998 A0127_06975 c31857a9cd059f19bf2faf7b1b44ee86 345 Pfam PF01594 AI-2E family transporter 11 322 2.6E-35 T 23-10-2018 IPR002549 Transmembrane protein TqsA-like A0127_00595 f007f7f145e0e1ba8cad576d7a7ca8be 279 SMART SM00650 30 193 5.8E-77 T 23-10-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 A0127_00595 f007f7f145e0e1ba8cad576d7a7ca8be 279 Pfam PF00398 Ribosomal RNA adenine dimethylase 17 226 1.0E-52 T 23-10-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm A0127_00595 f007f7f145e0e1ba8cad576d7a7ca8be 279 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 15 264 3.8E-77 T 23-10-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 A0127_00595 f007f7f145e0e1ba8cad576d7a7ca8be 279 SUPERFAMILY SSF53335 11 268 4.14E-61 T 23-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase A0127_00595 f007f7f145e0e1ba8cad576d7a7ca8be 279 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 46 73 - T 23-10-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 A0127_00595 f007f7f145e0e1ba8cad576d7a7ca8be 279 Gene3D G3DSA:1.10.8.100 195 272 4.8E-10 T 23-10-2018 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201|Reactome: R-HSA-6793080 A0127_00595 f007f7f145e0e1ba8cad576d7a7ca8be 279 Gene3D G3DSA:3.40.50.150 2 193 3.5E-63 T 23-10-2018 A0127_00595 f007f7f145e0e1ba8cad576d7a7ca8be 279 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 14 267 46.856 T 23-10-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 A0127_01895 cec89d8a378e335222175b0c5c7f1df3 154 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 11 151 7.4E-28 T 23-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 A0127_01895 cec89d8a378e335222175b0c5c7f1df3 154 Gene3D G3DSA:3.30.479.10 9 152 1.5E-31 T 23-10-2018 IPR038418 6-pyruvoyl tetrahydropterin synthase/QueD superfamily Reactome: R-HSA-1474151 A0127_01895 cec89d8a378e335222175b0c5c7f1df3 154 SUPERFAMILY SSF55620 12 152 2.72E-34 T 23-10-2018 A0127_03595 3007cf7246088c97099a7277faee4369 189 Pfam PF01066 CDP-alcohol phosphatidyltransferase 25 89 1.7E-15 T 23-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 A0127_03595 3007cf7246088c97099a7277faee4369 189 Gene3D G3DSA:1.20.120.1760 6 189 1.7E-49 T 23-10-2018 A0127_03595 3007cf7246088c97099a7277faee4369 189 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 67 89 - T 23-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 A0127_02085 e9b59e13a3291d6c60a5d6fa82bee4c5 108 Gene3D G3DSA:1.10.10.1220 1 88 2.0E-40 T 23-10-2018 A0127_09940 46edd6fe22f3088dcd69a4bc1e08173d 243 Pfam PF01925 Sulfite exporter TauE/SafE 7 241 3.2E-56 T 23-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 A0127_06085 b7e3f24ad88f2dbef59d3569bfc25963 81 Pfam PF01998 Protein of unknown function DUF131 31 73 2.1E-14 T 23-10-2018 IPR002849 Protein of unknown function DUF131 A0127_07840 0ca25504917ee6b576255e4545d17db4 251 SUPERFAMILY SSF53218 2 206 8.11E-40 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily A0127_07840 0ca25504917ee6b576255e4545d17db4 251 Gene3D G3DSA:3.40.980.10 2 179 4.3E-53 T 23-10-2018 IPR036425 MoaB/Mog-like domain superfamily A0127_07840 0ca25504917ee6b576255e4545d17db4 251 Pfam PF00994 Probable molybdopterin binding domain 4 176 1.1E-34 T 23-10-2018 IPR001453 MoaB/Mog domain A0127_07840 0ca25504917ee6b576255e4545d17db4 251 SMART SM00852 4 179 1.8E-39 T 23-10-2018 IPR001453 MoaB/Mog domain A0127_02895 062b87ee7b5f9c912f1135429bb09440 102 Pfam PF02517 CAAX protease self-immunity 2 90 1.1E-13 T 23-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 A0127_04935 3bdb78959c62ce62b091ee68356c6409 266 ProDom PD359573 MEMBRANE TRANSMEMBRANE AF2132 PROTEIN 1 235 1.0E-39 T 23-10-2018 A0127_08195 4307dab78330fd4ffd9e422731b6694b 234 Pfam PF13367 Protease prsW family 31 203 6.5E-32 T 23-10-2018 IPR026898 Protease PrsW GO:0008233 A0127_08195 4307dab78330fd4ffd9e422731b6694b 234 PIRSF PIRSF016933 4 226 4.3E-34 T 23-10-2018 IPR023596 Peptidase PrsW, archaeal/bacterial GO:0008233 A0127_06930 6933681260bf4792c1b59b86b8407917 216 Pfam PF01914 MarC family integral membrane protein 9 214 4.2E-60 T 23-10-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 A0127_06930 6933681260bf4792c1b59b86b8407917 216 TIGRFAM TIGR00427 TIGR00427: membrane protein, MarC family 7 210 3.0E-60 T 23-10-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 A0127_06065 a2efbcbe842f373c705d4cc65bf054f5 198 Pfam PF12389 Camelysin metallo-endopeptidase 9 98 3.2E-5 T 23-10-2018 IPR022121 Peptidase M73, camelysin A0127_05695 1ff1605a3ee225a8bbcf13dc992162bb 571 Pfam PF13245 AAA domain 10 281 3.5E-17 T 23-10-2018 A0127_05695 1ff1605a3ee225a8bbcf13dc992162bb 571 Pfam PF13361 UvrD-like helicase C-terminal domain 408 565 5.7E-11 T 23-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 A0127_05695 1ff1605a3ee225a8bbcf13dc992162bb 571 Gene3D G3DSA:3.40.50.300 8 300 2.6E-29 T 23-10-2018 A0127_05695 1ff1605a3ee225a8bbcf13dc992162bb 571 SUPERFAMILY SSF52540 11 566 4.33E-51 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_08310 025138c19a18bdf17d6fd4066753f0a4 78 Pfam PF01554 MatE 28 75 1.9E-8 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A0127_05080 4dc9181ba898db8e8184f9e1fd8f9b32 255 PIRSF PIRSF006648 1 245 4.7E-22 T 23-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 A0127_05080 4dc9181ba898db8e8184f9e1fd8f9b32 255 Pfam PF01061 ABC-2 type transporter 35 210 5.8E-17 T 23-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 A0127_01010 2f3d29f6a4f829271c34eb2f9de8b261 75 Pfam PF16286 Domain of unknown function (DUF4932) 2 57 3.3E-10 T 23-10-2018 IPR032560 Protein of unknown function DUF4932 A0127_05990 845e78bc2daf4643cf68084826856a27 136 SUPERFAMILY SSF48239 25 91 3.61E-5 T 23-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid A0127_01210 4177db642b8121b34f852095467e78b6 418 SUPERFAMILY SSF46785 206 323 5.9E-5 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A0127_01210 4177db642b8121b34f852095467e78b6 418 SUPERFAMILY SSF52540 12 147 3.48E-10 T 23-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase A0127_03880 3b3cebccd02da80a34904b1ce437b84a 236 SUPERFAMILY SSF102114 26 172 9.29E-20 T 23-10-2018 A0127_03880 3b3cebccd02da80a34904b1ce437b84a 236 Gene3D G3DSA:3.20.20.70 3 182 2.0E-22 T 23-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 A0127_03880 3b3cebccd02da80a34904b1ce437b84a 236 Pfam PF04055 Radical SAM superfamily 26 169 1.6E-14 T 23-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 A0127_03880 3b3cebccd02da80a34904b1ce437b84a 236 Pfam PF13353 4Fe-4S single cluster domain 18 98 6.8E-9 T 23-10-2018 A0127_03880 3b3cebccd02da80a34904b1ce437b84a 236 TIGRFAM TIGR02495 NrdG2: anaerobic ribonucleoside-triphosphate reductase activating protein 3 191 7.0E-50 T 23-10-2018 IPR012840 Anaerobic ribonucleoside-triphosphate reductase activating protein A0127_08620 04e1939815d52112067a5e204ca10aef 123 Gene3D G3DSA:3.40.140.10 2 123 1.5E-29 T 23-10-2018 A0127_08620 04e1939815d52112067a5e204ca10aef 123 Pfam PF14464 Prokaryotic homologs of the JAB domain 10 102 3.9E-11 T 23-10-2018 IPR028090 JAB domain, prokaryotic A0127_08620 04e1939815d52112067a5e204ca10aef 123 SUPERFAMILY SSF102712 2 121 3.01E-30 T 23-10-2018 A0127_04470 6e53e484b54ae04fb1d4c6f95fac0be7 435 Gene3D G3DSA:3.40.50.620 218 409 2.2E-35 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A0127_04470 6e53e484b54ae04fb1d4c6f95fac0be7 435 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 236 402 2.4E-35 T 23-10-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824 Reactome: R-HSA-196843 A0127_04470 6e53e484b54ae04fb1d4c6f95fac0be7 435 SUPERFAMILY SSF52402 224 391 2.21E-34 T 23-10-2018 A0127_07495 ea1a7199aba7e0ca883cf7c28845cbc4 156 TIGRFAM TIGR01038 uL22_arch_euk: ribosomal protein uL22 8 153 3.6E-67 T 23-10-2018 IPR005721 Ribosomal protein L22/L17, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_07495 ea1a7199aba7e0ca883cf7c28845cbc4 156 Gene3D G3DSA:3.90.470.10 6 156 4.4E-53 T 23-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 A0127_07495 ea1a7199aba7e0ca883cf7c28845cbc4 156 ProSitePatterns PS00464 Ribosomal protein L22 signature. 127 151 - T 23-10-2018 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_07495 ea1a7199aba7e0ca883cf7c28845cbc4 156 Pfam PF00237 Ribosomal protein L22p/L17e 21 151 2.3E-34 T 23-10-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 A0127_07495 ea1a7199aba7e0ca883cf7c28845cbc4 156 SUPERFAMILY SSF54843 8 153 3.01E-47 T 23-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 A0127_07495 ea1a7199aba7e0ca883cf7c28845cbc4 156 Hamap MF_01331_A 50S ribosomal protein L22 [rplV]. 4 154 33.781 T 23-10-2018 IPR005721 Ribosomal protein L22/L17, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_07635 da4200c356beeceb47c3f808a2ff3330 280 ProDom PD359573 MEMBRANE TRANSMEMBRANE AF2132 PROTEIN 34 173 1.0E-61 T 23-10-2018 A0127_01885 fade171cb1319c0b729df6ff2202d6c0 139 Pfam PF03479 Domain of unknown function (DUF296) 7 118 1.4E-23 T 23-10-2018 IPR005175 PPC domain A0127_01885 fade171cb1319c0b729df6ff2202d6c0 139 PIRSF PIRSF016702 1 139 5.3E-46 T 23-10-2018 IPR025707 Predicted DNA-binding protein with PD1-like DNA-binding motif A0127_01885 fade171cb1319c0b729df6ff2202d6c0 139 SUPERFAMILY SSF117856 4 126 6.28E-37 T 23-10-2018 A0127_01885 fade171cb1319c0b729df6ff2202d6c0 139 Gene3D G3DSA:3.30.1330.80 1 139 1.4E-48 T 23-10-2018 A0127_09390 4c737f6d2fdc316137e85e7536ca6ee6 85 Pfam PF13244 Domain of unknown function (DUF4040) 18 80 6.2E-12 T 23-10-2018 IPR025383 Domain of unknown function DUF4040 A0127_03640 fd61b77893c42d80da90727655347a83 580 Pfam PF00482 Type II secretion system (T2SS), protein F 88 215 4.2E-9 T 23-10-2018 IPR018076 Type II secretion system F domain A0127_03640 fd61b77893c42d80da90727655347a83 580 Pfam PF00482 Type II secretion system (T2SS), protein F 338 462 1.1E-9 T 23-10-2018 IPR018076 Type II secretion system F domain A0127_03510 81143f076f8284cd89b1ac341a900103 138 Pfam PF01877 RNA binding 7 116 9.6E-18 T 23-10-2018 IPR002739 Uncharacterised protein family UPF0201 A0127_03510 81143f076f8284cd89b1ac341a900103 138 Hamap MF_01112 UPF0201 protein . 6 135 25.111 T 23-10-2018 IPR002739 Uncharacterised protein family UPF0201 A0127_03510 81143f076f8284cd89b1ac341a900103 138 Gene3D G3DSA:3.30.1440.10 1 137 9.6E-45 T 23-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_03510 81143f076f8284cd89b1ac341a900103 138 SUPERFAMILY SSF55282 7 137 5.0E-40 T 23-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 A0127_06485 fef2920f46113dbc7e6abb3de6a9f72a 329 Gene3D G3DSA:3.40.50.880 50 217 8.7E-6 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A0127_06485 fef2920f46113dbc7e6abb3de6a9f72a 329 Pfam PF14258 Domain of unknown function (DUF4350) 37 105 2.4E-14 T 23-10-2018 IPR025646 Domain of unknown function DUF4350 A0127_06485 fef2920f46113dbc7e6abb3de6a9f72a 329 SUPERFAMILY SSF52317 62 229 3.66E-8 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A0127_08145 892d08c64d4dbe3c8f6984b68304c6b4 453 Gene3D G3DSA:1.20.1250.20 4 275 2.5E-34 T 23-10-2018 A0127_08145 892d08c64d4dbe3c8f6984b68304c6b4 453 Gene3D G3DSA:1.20.1250.20 276 444 9.6E-16 T 23-10-2018 A0127_08145 892d08c64d4dbe3c8f6984b68304c6b4 453 SUPERFAMILY SSF103473 8 436 1.57E-58 T 23-10-2018 IPR036259 MFS transporter superfamily A0127_08145 892d08c64d4dbe3c8f6984b68304c6b4 453 Pfam PF07690 Major Facilitator Superfamily 12 261 6.6E-32 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A0127_08145 892d08c64d4dbe3c8f6984b68304c6b4 453 Pfam PF07690 Major Facilitator Superfamily 282 434 3.0E-17 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A0127_09375 8b775d1b06ef3f98c1aafd8bbf7cbe61 635 Pfam PF00361 Proton-conducting membrane transporter 122 417 8.6E-27 T 23-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A0127_04765 d0742c5fb64660a660108570d21687b7 211 Pfam PF04252 Predicted SAM-dependent RNA methyltransferase 4 188 1.9E-45 T 23-10-2018 IPR007364 RNA methyltransferase TK0422/Sfm1 GO:0008168 A0127_06990 c86e89548ff394288b780e68f40cda12 227 Gene3D G3DSA:3.30.420.440 1 227 5.7E-108 T 23-10-2018 A0127_06990 c86e89548ff394288b780e68f40cda12 227 Pfam PF13680 Protein of unknown function (DUF4152) 1 224 4.2E-136 T 23-10-2018 IPR025206 Protein of unknown function DUF4152 A0127_06380 d92a1fbfdd2a36e2c034a2180011ac2d 255 Pfam PF05763 Protein of unknown function (DUF835) 126 242 2.4E-37 T 23-10-2018 IPR008553 Domain of unknown function DUF835 A0127_01640 d4db10a69356ee87450762318d6997b1 350 Pfam PF02653 Branched-chain amino acid transport system / permease component 60 332 4.7E-37 T 23-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 A0127_07760 4d65008665c3440a150386ccc687b447 173 Pfam PF03692 Putative zinc- or iron-chelating domain 24 129 6.0E-19 T 23-10-2018 IPR005358 Putative zinc- or iron-chelating domain containing protein A0127_08025 79311c0cc105034b6233854eb75ec89d 59 Pfam PF04021 Class III signal peptide 3 28 2.7E-9 T 23-10-2018 IPR007166 Class III signal peptide motif A0127_04125 e9195d92ae620803e3a9d6ff5ef6f868 163 Gene3D G3DSA:1.25.40.10 9 162 1.3E-7 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A0127_04125 e9195d92ae620803e3a9d6ff5ef6f868 163 SUPERFAMILY SSF48452 16 89 2.98E-6 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A0127_01515 4674a506bc5c35eb8702794ed5e63173 153 Pfam PF06695 Putative small multi-drug export protein 17 141 2.3E-30 T 23-10-2018 IPR009577 Putative small multi-drug export A0127_00600 b93624caea6be955cd83df04d5bdd2a5 168 SUPERFAMILY SSF47240 19 166 2.16E-6 T 23-10-2018 IPR009078 Ferritin-like superfamily A0127_00600 b93624caea6be955cd83df04d5bdd2a5 168 Gene3D G3DSA:1.20.1260.10 13 167 1.9E-12 T 23-10-2018 IPR012347 Ferritin-like A0127_02195 69f24b04bedc8cc4a35b0be3580ece1d 455 Pfam PF01554 MatE 253 414 4.6E-22 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A0127_02195 69f24b04bedc8cc4a35b0be3580ece1d 455 Pfam PF01554 MatE 28 188 1.9E-21 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A0127_02195 69f24b04bedc8cc4a35b0be3580ece1d 455 PIRSF PIRSF006603 2 455 5.7E-119 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A0127_02195 69f24b04bedc8cc4a35b0be3580ece1d 455 TIGRFAM TIGR00797 matE: MATE efflux family protein 28 424 6.8E-60 T 23-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 A0127_09025 a0a2ef16aa36122c214afa79e9f02044 492 Pfam PF02386 Cation transport protein 56 479 8.8E-67 T 23-10-2018 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 A0127_09025 a0a2ef16aa36122c214afa79e9f02044 492 TIGRFAM TIGR00933 2a38: potassium uptake protein, TrkH family 96 469 2.3E-109 T 23-10-2018 IPR004772 TrkH potassium transport family GO:0015379|GO:0016021|GO:0071805 A0127_06785 05c5a6f374262b8462892fbff51c6376 246 SUPERFAMILY SSF52402 51 190 7.15E-17 T 23-10-2018 A0127_06785 05c5a6f374262b8462892fbff51c6376 246 PIRSF PIRSF006601 1 246 6.5E-83 T 23-10-2018 IPR012096 ATPase, PP-loop, MJ1638-related A0127_06785 05c5a6f374262b8462892fbff51c6376 246 Gene3D G3DSA:3.40.50.620 55 197 1.6E-10 T 23-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold A0127_06720 9bb0bb5e98d47d7b4087daf4259a9c8d 197 Pfam PF06510 Protein of unknown function (DUF1102) 39 185 1.8E-57 T 23-10-2018 IPR009482 Protein of unknown function DUF1102 A0127_04030 6292c18559ccc49d605772c28c575668 87 Pfam PF01169 Uncharacterized protein family UPF0016 5 79 1.4E-22 T 23-10-2018 IPR001727 Gdt1 family A0127_00280 317e50431f5f733382ef927e34e11f43 73 ProDom PD052018 AF1456 COIL COILED 20 72 0.005 T 23-10-2018 A0127_09095 fe7b971e4a64bab262ea623cc0702288 209 Pfam PF09840 Uncharacterized protein conserved in archaea (DUF2067) 9 196 1.0E-54 T 23-10-2018 IPR019202 Protein of unknown function DUF2067 A0127_00940 f92b87351baeebc2fedddd0d5bcf9d35 109 Gene3D G3DSA:3.40.1260.10 2 109 2.3E-12 T 23-10-2018 IPR027396 DsrEFH-like A0127_06925 c6cb5933a09762d5f0147f616cafff5a 251 Pfam PF09874 Predicted membrane protein (DUF2101) 26 231 2.7E-86 T 23-10-2018 IPR018663 Protein of unknown function DUF2101, membrane A0127_10000 028e5fbf98cf8cdcdf28288d5fc5b378 233 Pfam PF13349 Putative adhesin 83 215 2.3E-8 T 23-10-2018 IPR025164 Putative adhesin A0127_02355 bca350b97b06355bde2215b548a0063d 247 SUPERFAMILY SSF55307 156 244 7.55E-12 T 23-10-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 A0127_02355 bca350b97b06355bde2215b548a0063d 247 Gene3D G3DSA:3.40.50.1440 104 245 2.2E-8 T 23-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 A0127_09710 5619a823972ec861b9ab7cbc47edb98b 219 Gene3D G3DSA:1.10.1760.20 1 208 2.4E-66 T 23-10-2018 A0127_09710 5619a823972ec861b9ab7cbc47edb98b 219 Pfam PF01891 Cobalt uptake substrate-specific transmembrane region 2 209 2.9E-57 T 23-10-2018 IPR002751 Metal transport protein CbiM/NikMN GO:0000041|GO:0016021 A0127_08615 125e47cd032fe6cd434401fbb4ae2731 262 Pfam PF10869 Protein of unknown function (DUF2666) 138 262 1.5E-48 T 23-10-2018 IPR022620 Protein of unknown function DUF2666 A0127_08615 125e47cd032fe6cd434401fbb4ae2731 262 Pfam PF10869 Protein of unknown function (DUF2666) 4 118 1.4E-12 T 23-10-2018 IPR022620 Protein of unknown function DUF2666 A0127_08615 125e47cd032fe6cd434401fbb4ae2731 262 ProDom PD033097 PH0063 MJ0596 ARCHAEAL PF2050 4 87 5.0E-38 T 23-10-2018 IPR022620 Protein of unknown function DUF2666 A0127_08615 125e47cd032fe6cd434401fbb4ae2731 262 ProDom PD033097 PH0063 MJ0596 ARCHAEAL PF2050 138 262 2.0E-65 T 23-10-2018 IPR022620 Protein of unknown function DUF2666 A0127_06710 b0820f89163842c574bdced17616b367 73 SUPERFAMILY SSF46785 7 71 4.07E-5 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A0127_04580 d4dd0b34af242bc7040e9c8c4f518411 592 Gene3D G3DSA:1.25.10.10 2 261 1.6E-68 T 23-10-2018 IPR011989 Armadillo-like helical A0127_04580 d4dd0b34af242bc7040e9c8c4f518411 592 Gene3D G3DSA:1.25.10.10 373 592 9.7E-8 T 23-10-2018 IPR011989 Armadillo-like helical A0127_04580 d4dd0b34af242bc7040e9c8c4f518411 592 SUPERFAMILY SSF48371 29 585 3.71E-28 T 23-10-2018 IPR016024 Armadillo-type fold A0127_06685 f3c492bfb6bf7224e265847e1086cc74 72 SUPERFAMILY SSF47598 5 46 1.48E-5 T 23-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 A0127_02390 126c02d79fee9dc61da393d911e2a548 644 Pfam PF05753 Translocon-associated protein beta (TRAPB) 289 391 1.1E-6 T 23-10-2018 A0127_00250 e5488634652862d102212745e31f2ecb 254 Pfam PF01925 Sulfite exporter TauE/SafE 8 244 6.3E-62 T 23-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 A0127_06675 c2c46b21ba3432c443dc7bd349099c51 311 SUPERFAMILY SSF64182 3 310 3.53E-26 T 23-10-2018 IPR038763 DHH phosphoesterase superfamily A0127_08640 9cf8b80e31706b55f012f59e4bc45257 239 Pfam PF01940 Integral membrane protein DUF92 11 215 6.1E-55 T 23-10-2018 IPR002794 Protein of unknown function DUF92, TMEM19 GO:0016021 A0127_04310 7b6724214ed93fed6c4eafa4115cd2d3 444 SMART SM00933 43 409 2.0E-24 T 23-10-2018 IPR018977 NurA domain A0127_04310 7b6724214ed93fed6c4eafa4115cd2d3 444 PIRSF PIRSF018871 1 444 9.2E-124 T 23-10-2018 IPR016738 DNA double-strand break repair nuclease NurA-like A0127_04310 7b6724214ed93fed6c4eafa4115cd2d3 444 Pfam PF09376 NurA domain 44 409 1.1E-64 T 23-10-2018 IPR018977 NurA domain A0127_02205 b17911cda09cbb0daa57fa86c335cec8 124 SUPERFAMILY SSF50993 2 80 1.1E-11 T 23-10-2018 A0127_08825 8a4ec05f69c13e0a7dd2183acd47db5f 495 Pfam PF00361 Proton-conducting membrane transporter 130 416 1.2E-63 T 23-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A0127_08825 8a4ec05f69c13e0a7dd2183acd47db5f 495 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 151 172 3.0E-8 T 23-10-2018 A0127_08825 8a4ec05f69c13e0a7dd2183acd47db5f 495 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 309 321 3.0E-8 T 23-10-2018 A0127_08825 8a4ec05f69c13e0a7dd2183acd47db5f 495 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 216 237 3.0E-8 T 23-10-2018 A0127_08825 8a4ec05f69c13e0a7dd2183acd47db5f 495 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 78 103 3.0E-8 T 23-10-2018 A0127_08825 8a4ec05f69c13e0a7dd2183acd47db5f 495 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 238 264 3.0E-8 T 23-10-2018 A0127_00975 e527b1419f930e0ff1e60f0f4183e005 390 SUPERFAMILY SSF103473 11 386 1.7E-39 T 23-10-2018 IPR036259 MFS transporter superfamily A0127_00975 e527b1419f930e0ff1e60f0f4183e005 390 Gene3D G3DSA:1.20.1250.20 210 389 5.7E-14 T 23-10-2018 A0127_00975 e527b1419f930e0ff1e60f0f4183e005 390 Pfam PF07690 Major Facilitator Superfamily 22 350 7.8E-17 T 23-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 A0127_00975 e527b1419f930e0ff1e60f0f4183e005 390 Gene3D G3DSA:1.20.1250.20 10 200 2.1E-14 T 23-10-2018 A0127_00975 e527b1419f930e0ff1e60f0f4183e005 390 ProSitePatterns PS00217 Sugar transport proteins signature 2. 104 129 - T 23-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 A0127_01265 20c70eb80547c899d20056f1a8292f66 306 Pfam PF01384 Phosphate transporter family 16 296 2.0E-52 T 23-10-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 A0127_05365 5936c78b72ea55d22aabcda483ab02ad 161 SUPERFAMILY SSF47240 12 152 1.52E-26 T 23-10-2018 IPR009078 Ferritin-like superfamily A0127_05365 5936c78b72ea55d22aabcda483ab02ad 161 Pfam PF02915 Rubrerythrin 16 152 1.2E-17 T 23-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 A0127_05365 5936c78b72ea55d22aabcda483ab02ad 161 Gene3D G3DSA:1.20.1260.10 6 155 1.2E-32 T 23-10-2018 IPR012347 Ferritin-like A0127_00660 5af938478f6d032796dc08a59a72b202 439 Pfam PF00999 Sodium/hydrogen exchanger family 12 404 1.7E-45 T 23-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 A0127_00660 5af938478f6d032796dc08a59a72b202 439 Gene3D G3DSA:1.20.1530.20 5 417 1.8E-67 T 23-10-2018 IPR038770 Sodium/solute symporter superfamily A0127_06000 e00a94ddb4055ed212465b0192a3888e 160 Gene3D G3DSA:1.50.10.20 56 160 3.9E-11 T 23-10-2018 A0127_06000 e00a94ddb4055ed212465b0192a3888e 160 SUPERFAMILY SSF48239 67 156 7.18E-11 T 23-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid A0127_01615 c0bb140f9e44a2fa544f0eea693875c7 215 Gene3D G3DSA:3.40.50.2020 6 181 4.4E-41 T 23-10-2018 A0127_01615 c0bb140f9e44a2fa544f0eea693875c7 215 SUPERFAMILY SSF53271 8 162 6.03E-36 T 23-10-2018 IPR029057 Phosphoribosyltransferase-like A0127_01615 c0bb140f9e44a2fa544f0eea693875c7 215 Pfam PF00156 Phosphoribosyl transferase domain 11 152 1.9E-21 T 23-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 A0127_09585 b4babf339de805bdadca4006884807f9 124 Pfam PF08859 DGC domain 14 91 6.4E-8 T 23-10-2018 IPR014958 DGC A0127_10300 32ea35cedaf49e81858c7ed5e0afa2f7 285 Pfam PF03239 Iron permease FTR1 family 3 260 4.5E-64 T 23-10-2018 IPR004923 Iron permease FTR1/Fip1/EfeU GO:0005381|GO:0016020|GO:0033573|GO:0034755 A0127_10230 bfbe0a03bb1278462c0c2fd2293986c8 160 Pfam PF03773 Predicted permease 31 158 1.9E-9 T 23-10-2018 IPR005524 Predicted permease DUF318 A0127_07725 0aace6e520a8bd2de34863fb68e70810 109 SUPERFAMILY SSF46785 4 107 1.85E-23 T 23-10-2018 IPR036390 Winged helix DNA-binding domain superfamily A0127_07725 0aace6e520a8bd2de34863fb68e70810 109 Pfam PF03551 Transcriptional regulator PadR-like family 21 94 1.1E-18 T 23-10-2018 IPR005149 Transcription regulator PadR, N-terminal A0127_07725 0aace6e520a8bd2de34863fb68e70810 109 Gene3D G3DSA:1.10.10.10 2 109 5.3E-26 T 23-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily A0127_08820 3c5fd58c9d010d9b404ad541ffa0d13f 114 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 5 111 1.3E-32 T 23-10-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like A0127_03535 a7f1811ef0b4f04d27e35247b00b44f3 99 Pfam PF09946 Predicted membrane protein (DUF2178) 7 88 1.1E-5 T 23-10-2018 IPR019235 Protein of unknown function DUF2178, transmembrane A0127_08910 462de7c2421bf9d73ed3bdc89daebfcf 181 Gene3D G3DSA:3.40.50.11570 1 180 6.8E-55 T 23-10-2018 A0127_08910 462de7c2421bf9d73ed3bdc89daebfcf 181 Pfam PF03192 Pyrococcus protein of unknown function, DUF257 4 177 4.0E-51 T 23-10-2018 IPR005489 Protein of unknown function DUF257 A0127_07290 7c51d1c95ea948475302f4a7800e59ff 169 Pfam PF03692 Putative zinc- or iron-chelating domain 16 127 7.2E-19 T 23-10-2018 IPR005358 Putative zinc- or iron-chelating domain containing protein A0127_03400 9f6df1365dc2a3b35cae597df085fb63 293 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 137 277 3.0E-8 T 23-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD A0127_03695 b915c27a8a36c7315778d24f37882582 223 Pfam PF01917 Archaebacterial flagellin 8 209 2.2E-49 T 23-10-2018 IPR002774 Flagellin, archaea GO:0005198|GO:0006928 A0127_03695 b915c27a8a36c7315778d24f37882582 223 TIGRFAM TIGR02537 arch_flag_Nterm: archaeal flagellin N-terminal-like domain 6 29 4.2E-6 T 23-10-2018 IPR013373 Flagellin/pilin, N-terminal A0127_06725 bde649d7714ecca2bd59cd6490766001 179 Pfam PF06510 Protein of unknown function (DUF1102) 37 176 9.6E-54 T 23-10-2018 IPR009482 Protein of unknown function DUF1102 A0127_09765 fed35d72ed582d25edc945dcd24e633c 303 SUPERFAMILY SSF53795 103 172 1.05E-5 T 23-10-2018 A0127_03660 565229369f77138e6e7b6d25f1a063cc 153 Pfam PF01917 Archaebacterial flagellin 4 69 1.1E-8 T 23-10-2018 IPR002774 Flagellin, archaea GO:0005198|GO:0006928 A0127_09065 dcfe709f11dc0dc0a88c14ee5d35de42 173 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 89 121 5.8E-7 T 23-10-2018 IPR001451 Hexapeptide repeat A0127_09065 dcfe709f11dc0dc0a88c14ee5d35de42 173 SUPERFAMILY SSF51161 2 168 3.19E-50 T 23-10-2018 IPR011004 Trimeric LpxA-like superfamily A0127_09065 dcfe709f11dc0dc0a88c14ee5d35de42 173 Gene3D G3DSA:2.160.10.10 1 172 1.4E-63 T 23-10-2018 A0127_01015 520c7737271da10605062b469a623d4d 213 Pfam PF16286 Domain of unknown function (DUF4932) 2 172 1.2E-28 T 23-10-2018 IPR032560 Protein of unknown function DUF4932 A0127_02525 9064558903608a2f85ed7e690d28481d 308 Pfam PF12679 ABC-2 family transporter protein 5 307 8.9E-64 T 23-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 A0127_07350 605fe94fa85b3214bc75b9b9ed779eb9 158 Gene3D G3DSA:3.40.50.300 7 158 9.0E-40 T 23-10-2018 A0127_05560 25ac3c25285b58fbd2492470257a507c 254 Pfam PF05763 Protein of unknown function (DUF835) 121 251 6.3E-36 T 23-10-2018 IPR008553 Domain of unknown function DUF835 A0127_03810 461903fe62ac64cf94020cee4a42757e 416 Gene3D G3DSA:1.25.40.10 4 144 3.3E-5 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A0127_03810 461903fe62ac64cf94020cee4a42757e 416 Gene3D G3DSA:1.25.40.10 145 235 2.4E-7 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A0127_03810 461903fe62ac64cf94020cee4a42757e 416 Gene3D G3DSA:1.25.40.10 257 408 4.0E-8 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A0127_09035 4f7e297d1b6e555a72f3c9d5078fd267 277 Gene3D G3DSA:1.25.40.10 19 208 5.2E-9 T 23-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 A0127_01665 58266e107ae8c649be9addb632fabf7f 269 Pfam PF02535 ZIP Zinc transporter 126 264 3.4E-19 T 23-10-2018 IPR003689 Zinc/iron permease GO:0016020|GO:0030001|GO:0046873|GO:0055085 A0127_04550 71f102ac87f0d71453f7790461d6a78e 264 Pfam PF07853 Protein of unknown function (DUF1648) 132 176 3.7E-15 T 23-10-2018 IPR012867 Domain of unknown function DUF1648 A0127_04550 71f102ac87f0d71453f7790461d6a78e 264 Pfam PF13630 SdpI/YhfL protein family 27 88 4.0E-12 T 23-10-2018 IPR025962 SdpI/YhfL protein family A0127_06235 ba8fba388cfa4f6ac7982ee925dde580 102 Gene3D G3DSA:3.30.720.70 1 102 9.1E-51 T 23-10-2018 A0127_01335 3f6ab72e01bcb65f7e96592f33746fba 342 SUPERFAMILY SSF52317 47 217 1.79E-7 T 23-10-2018 IPR029062 Class I glutamine amidotransferase-like A0127_04280 bcab775e6e57efc96309e87dba43efa6 275 Pfam PF05763 Protein of unknown function (DUF835) 137 267 2.4E-39 T 23-10-2018 IPR008553 Domain of unknown function DUF835 A0127_05180 d3edd282f28a4f6348b58e58493fdab1 440 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 8 415 1.8E-50 T 23-10-2018 IPR002823 Protein of unknown function DUF112, transmembrane A0127_00875 bf3659bd0269044610a316c23c4ad97c 362 Pfam PF03600 Citrate transporter 13 301 2.5E-25 T 23-10-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 A0127_07970 cc01974154267ba3eb543ca527be4c06 388 Gene3D G3DSA:3.40.50.300 1 184 6.7E-14 T 23-10-2018 A0127_03250 81866ab673d7bc2d8468153c1a632d62 59 Pfam PF07754 Domain of unknown function (DUF1610) 10 33 2.5E-14 T 23-10-2018 IPR011668 Domain of unknown function DUF1610 A0127_06965 c0ffb35d8bace431306669fe51993a7a 133 Pfam PF09999 Uncharacterized protein conserved in archaea (DUF2240) 8 60 9.8E-6 T 23-10-2018 IPR018716 Protein of unknown function DUF2240 A0127_05385 3a72bfdf15151edad7b192b0539342c3 177 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 19 171 2.7E-15 T 23-10-2018 IPR007404 LexA-binding, inner membrane-associated putative hydrolase A0127_04370 4d8cd9f732d0862c0e919a5a5aedf120 517 Pfam PF06662 D-glucuronyl C5-epimerase C-terminus 333 494 9.3E-44 T 23-10-2018 IPR010598 D-glucuronyl C5-epimerase, C-terminal KEGG: 00534+5.1.3.17|MetaCyc: PWY-6558|Reactome: R-HSA-2022928 A0127_04370 4d8cd9f732d0862c0e919a5a5aedf120 517 SUPERFAMILY SSF48208 344 499 4.54E-11 T 23-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 A0127_06740 5a53571d573592f1e7fe046836a590e6 320 Pfam PF17231 Family of unknown function (DUF5305) 120 317 2.2E-8 T 23-10-2018 IPR035185 Protein of unknown function DUF5305 A0127_09125 397fbf386c79ed14b736df6a998d7e3f 331 Pfam PF01594 AI-2E family transporter 10 322 1.9E-30 T 23-10-2018 IPR002549 Transmembrane protein TqsA-like A0127_06660 65f4b94560cdd60aa5ad9000009cf1f7 71 Pfam PF10049 Protein of unknown function (DUF2283) 2 50 8.9E-20 T 23-10-2018 IPR019270 Protein of unknown function DUF2283 A0127_06530 d31fabf13bbcb15a73d55d5ae4a80703 698 Pfam PF09971 Predicted membrane protein (DUF2206) 335 695 3.3E-52 T 23-10-2018 IPR018701 Protein of unknown function DUF2206, membrane A0127_06275 e102da3305129fef9552937036def8f8 386 Pfam PF16162 Domain of unknown function (DUF4868) 167 348 1.8E-6 T 23-10-2018 IPR032359 Protein of unknown function DUF4868 A0127_03200 4ecc9a39a338a3ce4cdce90b0d6ae88d 143 Pfam PF04024 PspC domain 3 61 1.5E-20 T 23-10-2018 IPR007168 Phage shock protein, PspC, N-terminal A0127_02980 04f2ccc42108beb9ff3e218fa2696c68 221 Gene3D G3DSA:3.40.50.300 3 215 1.0E-42 T 23-10-2018 A0127_10155 c068ad4b6b82e325eefd39ef47c4fbbe 78 Pfam PF09851 Short C-terminal domain 50 76 5.5E-10 T 23-10-2018 IPR018649 SHOCT domain A0127_04100 9fd0b71ceb8f577e08bd1acb87b78fde 298 Pfam PF00953 Glycosyl transferase family 4 67 211 2.7E-32 T 23-10-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 A0127_05200 72c81c33b5f5d32a59b580bd78571395 216 SUPERFAMILY SSF56112 9 155 7.49E-13 T 23-10-2018 IPR011009 Protein kinase-like domain superfamily A0127_05355 a692730fe5913b0f82bf80d209b93f39 330 Pfam PF00146 NADH dehydrogenase 16 324 9.3E-60 T 23-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 A0127_08750 99010f31c1b651f77682dd02e3dc0d21 183 Pfam PF01944 Stage II sporulation protein M 12 177 6.1E-35 T 23-10-2018 IPR002798 Stage II sporulation protein M-like A0127_04375 48122857bbbbff35e8077e4926158de9 194 Gene3D G3DSA:1.10.1760.20 3 193 1.3E-21 T 23-10-2018