locus-tag	class	description
A7C91_00010	ENOG410695F	Crispr-associated protein, Csm1 family
A7C91_00020	ENOG4108W8W	CRISPR-associated RAMP protein, Csm3 family
A7C91_00040	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
A7C91_00050	ENOG4105CK2	sodium dicarboxylate symporter
A7C91_00060	ENOG41061GT	Aldolase
A7C91_00065	ENOG4107QSA	Oxaloacetate decarboxylase
A7C91_00095	ENOG4105E8V	Alpha Beta Hydrolase Fold protein
A7C91_00115	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
A7C91_00130	ENOG4107R21	site-determining protein
A7C91_00145	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
A7C91_00200	ENOG4105VYW	UPF0251 protein
A7C91_00205	ENOG4105C83	adenylosuccinate lyase
A7C91_00230	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
A7C91_00275	ENOG4107QRT	dEAD DEAH box helicase
A7C91_00280	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
A7C91_00285	ENOG4105C5X	domain protein
A7C91_00295	ENOG4105F8V	Hydrolase, tatD family
A7C91_00330	ENOG4107EEM	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
A7C91_00340	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
A7C91_00385	ENOG4105C11	sulfate adenylyltransferase), subunit 2
A7C91_00400	ENOG41080U2	Amidohydrolase family
A7C91_00405	ENOG4105C5S	asparaginyl-tRNA synthetase
A7C91_00420	ENOG4105DP9	ABC transporter
A7C91_00440	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
A7C91_00455	ENOG4105VKD	bioY protein
A7C91_00460	ENOG4108JJB	ABC transporter
A7C91_00465	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
A7C91_00510	ENOG4107QVT	Binding-protein-dependent transport systems, inner membrane component
A7C91_00515	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
A7C91_00540	ENOG4105BZA	Phosphoglycerate kinase
A7C91_00565	ENOG4105CSM	endonuclease III
A7C91_00595	ENOG4105CD5	CoA-binding domain protein
A7C91_00605	ENOG4105C6T	cysteine synthase
A7C91_00625	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
A7C91_00650	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
A7C91_00660	ENOG4105PW4	Sugar fermentation stimulation protein homolog
A7C91_00665	ENOG4105CN9	Peptidase m42 family protein
A7C91_00680	ENOG4105DVT	helicase
A7C91_00695	ENOG4105C1J	atp-dependent rna helicase
A7C91_00725	ENOG4107QW4	alcohol dehydrogenase
A7C91_00740	ENOG4105P4J	Allophanate hydrolase, subunit 1
A7C91_00745	ENOG4105E7W	lamb ycsf family protein
A7C91_00780	ENOG4107QX8	SPFH domain, Band 7 family protein
A7C91_00800	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
A7C91_00815	ENOG4108RCS	geranylgeranylglyceryl phosphate synthase
A7C91_00865	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
A7C91_00885	ENOG4105D5P	Methylmalonyl-coA mutase
A7C91_00890	ENOG4107SSZ	Phosphatase
A7C91_00895	ENOG4108Z03	MAF-like protein
A7C91_00900	ENOG4105CTP	PilT protein domain protein
A7C91_00905	ENOG4107QMS	site-determining protein
A7C91_00915	ENOG4105CAQ	asparagine synthetase
A7C91_00925	ENOG4107QPH	glycogen) synthase
A7C91_00930	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
A7C91_00950	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
A7C91_00955	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
A7C91_00965	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
A7C91_00980	ENOG4105CD5	CoA-binding domain protein
A7C91_01020	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
A7C91_01075	ENOG4107Y70	Heat shock protein
A7C91_01155	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
A7C91_01235	ENOG4105EAC	phosphoserine phosphatase
A7C91_01255	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
A7C91_01310	ENOG4105EAC	phosphoserine phosphatase
A7C91_01315	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
A7C91_01380	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
A7C91_01400	ENOG4108V3W	Chemotaxis protein, CheW
A7C91_01405	ENOG4105C8Q	Methyl-accepting chemotaxis
A7C91_01410	ENOG4105BZU	Histidine kinase
A7C91_01415	ENOG4107YTP	response regulator receiver protein
A7C91_01420	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
A7C91_01425	ENOG4105CBS	Chea signal transduction histidine kinase
A7C91_01440	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
A7C91_01445	ENOG4105C8Q	Methyl-accepting chemotaxis
A7C91_01495	ENOG4106IPI	cyclase, family
A7C91_01500	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
A7C91_01510	ENOG4108R96	Methyltransferase, YaeB family
A7C91_01520	ENOG4108I5D	sulfate abc transporter
A7C91_01525	ENOG41066FR	extracellular solute-binding protein
A7C91_01540	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
A7C91_01545	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
A7C91_01610	ENOG4108IYI	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
A7C91_01615	ENOG4107104	thymidine kinase
A7C91_01665	ENOG4108IUW	ABC transporter
A7C91_01700	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
A7C91_01710	ENOG4107QJE	Chromosome Partitioning Protein
A7C91_01715	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
A7C91_01730	ENOG4105CHM	Aminotransferase
A7C91_01770	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
A7C91_01900	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
A7C91_01905	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
A7C91_01940	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
A7C91_01950	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
A7C91_01985	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
A7C91_01995	ENOG4105D0M	Protease HtpX homolog
A7C91_02020	ENOG4105CK7	Sodium proline symporter
A7C91_02035	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
A7C91_02045	ENOG4108Z0Z	intracellular protease Pfpi family
A7C91_02080	ENOG4108UKZ	OsmC family
A7C91_02090	ENOG4108Z86	Glutamine amidotransferase
A7C91_02095	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
A7C91_02100	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
A7C91_02125	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
A7C91_02130	ENOG4105CHU	acetyl-coa acetyltransferase
A7C91_02190	ENOG4107WCI	zn-dependent hydrolase of the beta-lactamase fold-like protein
A7C91_02230	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
A7C91_02250	ENOG4108JPZ	Monovalent cation H antiporter subunit D
A7C91_02275	ENOG4105KJM	monovalent cation h antiporter subunit g
A7C91_02280	ENOG41080TA	Multiple resistance and ph regulation protein f
A7C91_02285	ENOG4105SC1	monovalent cation H antiporter subunit E
A7C91_02310	ENOG4105BZ8	glutamate synthase
A7C91_02315	ENOG4105CDJ	oxidoreductase FAD NAD(P)-binding domain protein
A7C91_02355	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
A7C91_02360	ENOG4105DUN	Mediates zinc uptake. May also transport other divalent cations (By similarity)
A7C91_02375	ENOG4105CJ1	ABC, transporter
A7C91_02385	ENOG4105VZ8	Transcriptional regulator
A7C91_02425	ENOG4105CDJ	oxidoreductase FAD NAD(P)-binding domain protein
A7C91_02430	ENOG4105BZ8	glutamate synthase
A7C91_02450	ENOG41084T3	4fe-4S ferredoxin iron-sulfur binding domain-containing protein
A7C91_02460	ENOG4105VG1	fes assembly suf system protein
A7C91_02470	ENOG4108JVH	Protein of unknown function DUF43
A7C91_02485	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
A7C91_02495	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
A7C91_02510	ENOG4105D0M	Protease HtpX homolog
A7C91_02515	ENOG4108UK2	deaminase
A7C91_02530	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
A7C91_02540	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
A7C91_02545	ENOG4105DJB	Major Facilitator Superfamily
A7C91_02565	ENOG4105C6X	Major Facilitator
A7C91_02570	ENOG4105D44	asparaginase
A7C91_02590	ENOG4105DK7	lysyl-tRNA synthetase
A7C91_02630	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
A7C91_02645	ENOG4105E8R	UPF0173 metal-dependent hydrolase
A7C91_02650	ENOG4105EHU	Circadian clock protein KaiC
A7C91_02665	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
A7C91_02680	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
A7C91_02685	ENOG4105D1H	recombination factor protein RarA
A7C91_02690	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
A7C91_02720	ENOG4107WZZ	SMC domain protein
A7C91_02720	ENOG4107WZZ	SMC domain protein
A7C91_02735	ENOG4105EHG	Permease protein
A7C91_02740	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
A7C91_02745	ENOG4105F7N	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation (By similarity)
A7C91_02760	ENOG4105NBF	ammecr1 domain protein
A7C91_02795	ENOG4107ZCS	Phosphomethylpyrimidine kinase
A7C91_02800	ENOG4105CXT	aspartate transcarbamylase
A7C91_02805	ENOG4108R9M	Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity)
A7C91_02855	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
A7C91_02860	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
A7C91_02875	ENOG4107V9E	glucose-1-phosphate thymidylyltransferase
A7C91_02895	ENOG4105CNB	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
A7C91_02925	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
A7C91_02965	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
A7C91_02975	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
A7C91_03015	ENOG4105M7V	2'-5' rna ligase
A7C91_03045	ENOG4105WE2	aldehyde ferredoxin oxidoreductase
A7C91_03055	ENOG4108594	Permease of the drug metabolite transporter
A7C91_03065	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
A7C91_03095	ENOG4108NGU	Transcriptional regulator
A7C91_03130	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
A7C91_03135	ENOG4105EPD	Oligopeptide transporter, Opt family
A7C91_03145	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
A7C91_03165	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
A7C91_03190	ENOG4105EHU	Circadian clock protein KaiC
A7C91_03230	ENOG4105C5F	glutamine synthetase
A7C91_03240	ENOG4105C4K	Nad synthetase
A7C91_03250	ENOG4108JQ7	(ABC) transporter
A7C91_03255	ENOG4105C3U	ABC transporter
A7C91_03260	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
A7C91_03295	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
A7C91_03300	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
A7C91_03305	ENOG4107SDU	Methyl-accepting chemotaxis
A7C91_03315	ENOG4105M56	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
A7C91_03325	ENOG4108JIQ	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit (By similarity)
A7C91_03360	ENOG4105C1A	potassium transporter peripheral membrane
A7C91_03365	ENOG4105C3D	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
A7C91_03370	ENOG4108JIS	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
A7C91_03375	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
A7C91_03385	ENOG4105EHU	Circadian clock protein KaiC
A7C91_03415	ENOG4107XF7	NGG1p interacting factor 3 protein, NIF3
A7C91_03430	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
A7C91_03445	ENOG4105CUT	histidyl-tRNA synthetase
A7C91_03470	ENOG4105DZ0	fad dependent oxidoreductase
A7C91_03480	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
A7C91_03535	ENOG4107RIQ	Sulfate adenylate transferase
A7C91_03550	ENOG4107T1U	Catalyzes the synthesis of activated sulfate (By similarity)
A7C91_03575	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
A7C91_03585	ENOG4105J5G	Transferase hexapeptide repeat containing protein
A7C91_03605	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
A7C91_03625	ENOG4105C0H	protease
A7C91_03630	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
A7C91_03650	ENOG4108KN7	Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity)
A7C91_03655	ENOG4107SCK	Monooxygenase
A7C91_03680	ENOG4105CTD	carboxy-peptidase
A7C91_03700	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
A7C91_03725	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
A7C91_03760	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
A7C91_03765	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
A7C91_03780	ENOG4105ERH	Fumarylacetoacetate hydrolase
A7C91_03795	ENOG4105C31	Tryptophanyl-tRNA synthetase
A7C91_03800	ENOG4105CD5	CoA-binding domain protein
A7C91_03805	ENOG4107QWE	)-transporter
A7C91_03810	ENOG41082SX	arsR family transcriptional regulator
A7C91_03855	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
A7C91_03875	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
A7C91_03890	ENOG4105CB1	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
A7C91_03915	ENOG4105EYW	Ion transport protein
A7C91_03980	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
A7C91_03990	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
A7C91_04050	ENOG41081QJ	UBA THIF-type NAD FAD binding
A7C91_04060	ENOG4108ZAF	Molybdopterin
A7C91_04080	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
A7C91_04085	ENOG4108VVK	transcriptional Regulator, AsnC
A7C91_04095	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
A7C91_04110	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
A7C91_04125	ENOG4108JPW	Aminotransferase
A7C91_04130	ENOG4105C3M	thioredoxin reductase
A7C91_04150	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
A7C91_04155	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
A7C91_04170	ENOG4107TDF	Formate hydrogenlyase subunit 4
A7C91_04180	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
A7C91_04185	ENOG4105C47	NADH ubiquinone oxidoreductase 20 kda subunit
A7C91_04195	ENOG4108JPZ	Monovalent cation H antiporter subunit D
A7C91_04200	ENOG4105MKQ	Monovalent cation H antiporter subunit C
A7C91_04220	ENOG4105KJM	monovalent cation h antiporter subunit g
A7C91_04230	ENOG4105SC1	monovalent cation H antiporter subunit E
A7C91_04235	ENOG41083NF	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
A7C91_04240	ENOG4108JPZ	Monovalent cation H antiporter subunit D
A7C91_04255	ENOG4108PMQ	Na H antiporter MnhB subunit-related protein
A7C91_04265	ENOG4105KJM	monovalent cation h antiporter subunit g
A7C91_04275	ENOG4105TMB	Formate nitrite transporter
A7C91_04285	ENOG4105C47	NADH ubiquinone oxidoreductase 20 kda subunit
A7C91_04290	ENOG4108RG7	formate hydrogenlyase complex iron-sulfur subunit
A7C91_04305	ENOG4108JPZ	Monovalent cation H antiporter subunit D
A7C91_04310	ENOG4108JPZ	Monovalent cation H antiporter subunit D
A7C91_04315	ENOG4105D65	subunit l
A7C91_04320	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
A7C91_04325	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
A7C91_04345	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
A7C91_04350	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
A7C91_04375	ENOG4105CJ3	phosphate transporter
A7C91_04400	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
A7C91_04425	ENOG4108IGT	Dipeptidase
A7C91_04440	ENOG4105VFR	signal peptidase
A7C91_04445	ENOG4107S5Z	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity)
A7C91_04495	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
A7C91_04500	ENOG4105E2Z	phosphate ABC transporter (Permease
A7C91_04545	ENOG4105ZHF	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
A7C91_04550	ENOG4105VAW	lrga family
A7C91_04575	ENOG4108S8N	class II Aldolase
A7C91_04585	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
A7C91_04630	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
A7C91_04635	ENOG4107S6Z	Na H antiporter
A7C91_04645	ENOG4107QIM	DNA ligase
A7C91_04655	ENOG4107YIW	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
A7C91_04665	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
A7C91_04670	ENOG4108VVK	transcriptional Regulator, AsnC
A7C91_04680	ENOG4107UX3	phosphatidylethanolamine N-methyltransferase
A7C91_04755	ENOG4105EWK	phytoene
A7C91_04785	ENOG4107NFR	Fructose-1,6-bisphosphatase
A7C91_04805	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
A7C91_04810	ENOG4107YZX	Universal stress protein
A7C91_04815	ENOG4108UUC	Protein of unknown function DUF99
A7C91_04825	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
A7C91_04835	ENOG4108RVA	ribokinase
A7C91_04860	ENOG4105D1F	ATP-binding protein
A7C91_04870	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
A7C91_04880	ENOG4105DDK	oxidoreductase, beta subunit
A7C91_04885	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
A7C91_04895	ENOG4105DDK	oxidoreductase, beta subunit
A7C91_04900	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
A7C91_04915	ENOG4105CJ3	phosphate transporter
A7C91_04920	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
A7C91_04935	ENOG4107RWR	Sodium hydrogen exchanger
A7C91_04960	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
A7C91_04965	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
A7C91_05020	ENOG4107R3E	Citrate transporter
A7C91_05040	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
A7C91_05070	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
A7C91_05105	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
A7C91_05155	ENOG4105CBG	Sulfatase
A7C91_05195	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
A7C91_05255	ENOG4105EHG	Permease protein
A7C91_05260	ENOG4108HWH	(ABC) transporter
A7C91_05265	ENOG4105CTK	cobaltochelatase, cobn subunit
A7C91_05270	ENOG4105EET	magnesium chelatase
A7C91_05305	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
A7C91_05310	ENOG4108IUW	ABC transporter
A7C91_05340	ENOG4108IYU	L-aspartate oxidase
A7C91_05350	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
A7C91_05360	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
A7C91_05380	ENOG4105C0D	helicase
A7C91_05420	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
A7C91_05425	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
A7C91_05435	ENOG4105C8V	SAICAR synthetase
A7C91_05440	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
A7C91_05445	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
A7C91_05450	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
A7C91_05455	ENOG4107QNG	Phosphoribosylglycinamide synthetase
A7C91_05470	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
A7C91_05475	ENOG4108JIU	phosphoribosylformylglycinamidine synthase ii
A7C91_05485	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
A7C91_05490	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
A7C91_05550	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
A7C91_05585	ENOG4105F0N	pyrophosphate phospho-hydrolase
A7C91_05645	ENOG4105IIU	Aminopeptidase
A7C91_05705	ENOG4105K8R	UPF0145 protein
A7C91_05715	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
A7C91_05735	ENOG4105D64	Mechanosensitive ion channel
A7C91_05760	ENOG4105EM7	Selenocysteine-specific translation elongation factor
A7C91_05785	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
A7C91_05790	ENOG410825M	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
A7C91_05865	ENOG4105C7N	Xanthine uracil vitamin C permease
A7C91_05875	ENOG4105ECW	sulfate abc transporter
A7C91_05905	ENOG4105NBF	ammecr1 domain protein
A7C91_05910	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
A7C91_05955	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
A7C91_05975	ENOG4105VUN	Transcriptional regulator
A7C91_05980	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
A7C91_05990	ENOG4108RWI	nicotinamidase
A7C91_05995	ENOG4105F4G	Membrane
A7C91_06015	ENOG4108M11	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
A7C91_06085	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
A7C91_06090	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
A7C91_06095	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
A7C91_06120	ENOG4105CJW	magnesium transporter
A7C91_06125	ENOG4105D9Q	decarboxylase (Beta subunit)
A7C91_06130	ENOG4107QSA	Oxaloacetate decarboxylase
A7C91_06140	ENOG4105D8K	carboxyl transferase
A7C91_06170	ENOG4105CKX	Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP
A7C91_06195	ENOG4105DF0	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity)
A7C91_06205	ENOG4105CDJ	oxidoreductase FAD NAD(P)-binding domain protein
A7C91_06215	ENOG4105C5S	asparaginyl-tRNA synthetase
A7C91_06230	ENOG4107STF	Involved in phosphonate degradation (By similarity)
A7C91_06260	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
A7C91_06270	ENOG4105KZR	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
A7C91_06275	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
A7C91_06280	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
A7C91_06285	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
A7C91_06290	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
A7C91_06295	ENOG41082SA	50s ribosomal protein l29
A7C91_06300	ENOG4108ZJT	translation initiation factor, Sui1
A7C91_06310	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
A7C91_06315	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
A7C91_06330	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
A7C91_06340	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
A7C91_06345	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
A7C91_06360	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
A7C91_06365	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
A7C91_06370	ENOG4105VPB	50S ribosomal protein L30
A7C91_06375	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
A7C91_06400	ENOG4108Z4J	Cytidine monophosphate kinase
A7C91_06410	ENOG4105CHR	reductase
A7C91_06415	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
A7C91_06430	ENOG4107Y49	methyltransferase
A7C91_06440	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
A7C91_06445	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
A7C91_06450	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
A7C91_06470	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
A7C91_06475	ENOG4108UJD	30S ribosomal protein S9
A7C91_06495	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
A7C91_06500	ENOG4105CE9	30S ribosomal protein S2
A7C91_06540	ENOG4108YXU	transcriptional regulator AsnC family
A7C91_06550	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
A7C91_06585	ENOG4105CB1	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
A7C91_06615	ENOG4108I5U	Uridine phosphorylase
A7C91_06625	ENOG41074MP	UPF0103 Mediator of ErbB2-driven cell motility-containing protein
A7C91_06640	ENOG4106UJV	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
A7C91_06645	ENOG4105CN5	Metallo-Beta-Lactamase
A7C91_06675	ENOG4105C8T	Leucyl-tRNA synthetase
A7C91_06680	ENOG4105EYF	MMPL domain protein
A7C91_06710	ENOG4108JEB	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
A7C91_06725	ENOG4105MRR	Transcriptional regulator (By similarity)
A7C91_06745	ENOG4108YZA	Nitrogen regulatory protein pii
A7C91_06755	ENOG4105C8J	)-transporter
A7C91_06760	ENOG4105D82	Glutamate dehydrogenase
A7C91_06770	ENOG4105KPK	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation (By similarity)
A7C91_06775	ENOG4105CY0	Metallo-Beta-Lactamase
A7C91_06790	ENOG4105E66	phosphoriboisomerase A
A7C91_06815	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
A7C91_06820	ENOG4105UQX	Mate efflux family protein
A7C91_06865	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
A7C91_06900	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
A7C91_06905	ENOG41080XS	Cobyrinic acid ac-diamide synthase
A7C91_06920	ENOG4105C45	hydrogenase expression formation protein (HypE)
A7C91_06930	ENOG4105CQS	hydrogenase expression formation protein HypD
A7C91_06940	ENOG41067SE	Tetr family transcriptional regulator
A7C91_06945	ENOG4108IEG	Formate dehydrogenase Alpha subunit
A7C91_06950	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
A7C91_06955	ENOG4105D65	subunit l
A7C91_06960	ENOG4108JPZ	Monovalent cation H antiporter subunit D
A7C91_06965	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
A7C91_06970	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
A7C91_06975	ENOG4108RG7	formate hydrogenlyase complex iron-sulfur subunit
A7C91_06980	ENOG4105C47	NADH ubiquinone oxidoreductase 20 kda subunit
A7C91_06995	ENOG4105KJM	monovalent cation h antiporter subunit g
A7C91_07010	ENOG4108ZE9	Monovalent cation H antiporter subunit C
A7C91_07020	ENOG4108JPZ	Monovalent cation H antiporter subunit D
A7C91_07030	ENOG41083NF	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
A7C91_07070	ENOG4105S10	periplasmic binding protein
A7C91_07075	ENOG4105EHG	Permease protein
A7C91_07080	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
A7C91_07090	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
A7C91_07105	ENOG4108Z4T	Peptidase M50
A7C91_07110	ENOG4108Y83	glucose-6-phosphate isomerase
A7C91_07145	ENOG4108JJB	ABC transporter
A7C91_07160	ENOG4105CFT	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import (By similarity)
A7C91_07175	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
A7C91_07235	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
A7C91_07255	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
A7C91_07275	ENOG4107QR0	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
A7C91_07285	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
A7C91_07315	ENOG4107RGW	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
A7C91_07370	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
A7C91_07375	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
A7C91_07380	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
A7C91_07390	ENOG4107TE1	transport protein
A7C91_07400	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
A7C91_07415	ENOG4105C0M	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity)
A7C91_07430	ENOG4105CX6	glutaminyL-tRNA synthetase
A7C91_07480	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
A7C91_07485	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
A7C91_07500	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
A7C91_07535	ENOG4108T9Q	UPF0278 protein
A7C91_07550	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
A7C91_07555	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
A7C91_07570	ENOG4108JU3	Alkyl hydroperoxide reductase
A7C91_07575	ENOG4105ZHF	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
A7C91_07585	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
A7C91_07595	ENOG4105KRN	Transcriptional regulator, abrb family
A7C91_07605	ENOG4105DTT	CRISPR-associated helicase, cas3
A7C91_07630	ENOG4105CD5	CoA-binding domain protein
A7C91_07650	ENOG4106K5Q	Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication (By similarity)
A7C91_07685	ENOG4108VA3	3-hexulose-6-phosphate synthase
A7C91_07695	ENOG4107XGZ	Hydrolase
A7C91_07720	ENOG4105C5S	asparaginyl-tRNA synthetase
A7C91_07735	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
A7C91_07750	ENOG4105CH2	amidohydrolase
A7C91_07775	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
A7C91_07795	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
A7C91_07805	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
A7C91_07810	ENOG4107V9E	glucose-1-phosphate thymidylyltransferase
A7C91_07820	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
A7C91_07835	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
A7C91_07840	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
A7C91_07845	ENOG4108JJB	ABC transporter
A7C91_07865	ENOG4105CN9	Peptidase m42 family protein
A7C91_07880	ENOG4108Z0R	Transferase
A7C91_07885	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
A7C91_07900	ENOG4105C22	threonyL-tRNA synthetase
A7C91_07905	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
A7C91_07945	ENOG4108REF	Sporulation integral membrane protein ytvi
A7C91_07950	ENOG4105EEI	dihydropteroate synthase
A7C91_07975	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
A7C91_07980	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
A7C91_07985	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
A7C91_07990	ENOG4107TIA	phenylalanyl-tRNA synthetase (beta subunit)
A7C91_08000	ENOG4105CPQ	Dehydrogenase
A7C91_08005	ENOG4107QMS	site-determining protein
A7C91_08020	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
A7C91_08025	ENOG4105HDK	L-asparaginase
A7C91_08055	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
A7C91_08065	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
A7C91_08090	ENOG4105F73	Catalyzes the deformylation of 4-deoxy-4-formamido-L- arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
A7C91_08095	ENOG4107XB0	Lipopolysaccharide 1,2-N-acetylglucosaminetransferase
A7C91_08105	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
A7C91_08120	ENOG4105CMQ	Chloride channel
A7C91_08185	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
A7C91_08190	ENOG4105DBV	ornithine carbamoyltransferase
A7C91_08200	ENOG41087GE	Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity)
A7C91_08225	ENOG4105E3H	phosphoglycerate mutase
A7C91_08230	ENOG4105CV8	reductase
A7C91_08250	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
A7C91_08275	ENOG4105BZR	domain protein
A7C91_08325	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
A7C91_08340	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
A7C91_08410	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
A7C91_08455	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
A7C91_08460	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
A7C91_08465	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
A7C91_08470	ENOG4108IZQ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
A7C91_08475	ENOG4108JPZ	Monovalent cation H antiporter subunit D
A7C91_08480	ENOG4108JPZ	Monovalent cation H antiporter subunit D
A7C91_08485	ENOG4105MKQ	Monovalent cation H antiporter subunit C
A7C91_08490	ENOG4105D65	subunit l
A7C91_08500	ENOG4105KJM	monovalent cation h antiporter subunit g
A7C91_08505	ENOG41080TA	Multiple resistance and ph regulation protein f
A7C91_08510	ENOG4105SC1	monovalent cation H antiporter subunit E
A7C91_08520	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
A7C91_08540	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
A7C91_08545	ENOG4108IJ1	Dehydrogenase
A7C91_08565	ENOG4105C75	arginyL-tRNA synthetase
A7C91_08570	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
A7C91_08640	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
A7C91_08660	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
A7C91_08670	ENOG4108VVK	transcriptional Regulator, AsnC
A7C91_08680	ENOG41066UM	arsR family transcriptional regulator
A7C91_08690	ENOG4105KME	endoribonuclease L-psp
A7C91_08700	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
A7C91_08705	ENOG4105C3K	feS assembly ATPase SufC
A7C91_08710	ENOG4105DIW	FeS assembly protein SUFB
A7C91_08750	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
A7C91_08755	ENOG4105QAX	Iron-sulfur
A7C91_08765	ENOG4105BZ8	glutamate synthase
A7C91_08780	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
A7C91_08825	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
A7C91_08835	ENOG4105DZH	s-adenosylmethionine synthetase (EC 2.5.1.6)
A7C91_08845	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
A7C91_08850	ENOG4105D0M	Protease HtpX homolog
A7C91_08860	ENOG4105CHM	Aminotransferase
A7C91_08875	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
A7C91_08880	ENOG4105C5I	Dehydrogenase
A7C91_08885	ENOG4105CN9	Peptidase m42 family protein
A7C91_08915	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
A7C91_08930	ENOG4105DQU	oxidoreductase, subunit beta
A7C91_08935	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
A7C91_08945	ENOG4105DQU	oxidoreductase, subunit beta
A7C91_08950	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
A7C91_08965	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
A7C91_08985	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
A7C91_08995	ENOG4105DIH	basic membrane
A7C91_09000	ENOG4108JQ9	ABC transporter
A7C91_09005	ENOG4105UIB	(ABC) transporter
A7C91_09030	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
A7C91_09035	ENOG4105C8N	cysteinyl-tRNA synthetase
A7C91_09055	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
A7C91_09065	ENOG4105DWF	phosphomethylpyrimidine kinase
A7C91_09070	ENOG4105IQJ	Involved in biosynthesis of the thiamine precursor thiazole (By similarity)
A7C91_09075	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
A7C91_09080	ENOG4105C8V	SAICAR synthetase
A7C91_09100	ENOG4105EHU	Circadian clock protein KaiC
A7C91_09105	ENOG4107QRT	dEAD DEAH box helicase
A7C91_09115	ENOG4107QJZ	Glycosyl transferase, family 2
A7C91_09155	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
A7C91_09195	ENOG4108WBT	adenosyltransferase
A7C91_09205	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
A7C91_09210	ENOG4105CEV	competence damage-inducible protein
A7C91_09225	ENOG4105VZ9	UPF0235 protein
A7C91_09235	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
A7C91_09250	ENOG4105UQX	Mate efflux family protein
A7C91_09270	ENOG4108K3F	N(2),N(2)-dimethylguanosine tRNA methyltransferase
A7C91_09285	ENOG4105DC7	peptidase M24
A7C91_09300	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
A7C91_09325	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
A7C91_09335	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
A7C91_09360	ENOG4105C3G	gtp-binding protein
A7C91_09375	ENOG4105NBF	ammecr1 domain protein
A7C91_09380	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
A7C91_09385	ENOG4105DA5	(ABC) transporter
A7C91_09410	ENOG4105CG9	aspartate racemase
A7C91_09415	ENOG4105C5X	domain protein
A7C91_09485	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
A7C91_09495	ENOG4108MIC	Mg-protoporphyrin IX methyl transferase
A7C91_09500	ENOG4105CIH	Imidazole acetol-phosphate transaminase
A7C91_09505	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
A7C91_09530	ENOG4108UHF	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
A7C91_09535	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
A7C91_09555	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
A7C91_09560	ENOG4108K7V	UPF0284 protein
A7C91_09570	ENOG4105EPU	Molybdenum cofactor synthesis domain protein
A7C91_09575	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
A7C91_09600	ENOG4105DCI	Phosphohydrolase
A7C91_09625	ENOG4105E0R	Deoxyhypusine synthase
A7C91_09630	ENOG4105BZ8	glutamate synthase
A7C91_09635	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
A7C91_09695	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
A7C91_09710	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
A7C91_09720	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
A7C91_09735	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
A7C91_09765	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
A7C91_09780	ENOG4105FDK	ABC transporter
A7C91_09800	ENOG4105F4P	)-transporter
A7C91_09880	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
A7C91_09885	ENOG4105WE2	aldehyde ferredoxin oxidoreductase
A7C91_09920	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
A7C91_09925	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
A7C91_09935	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
A7C91_09980	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
A7C91_09990	ENOG4105FBQ	ATPase associated with various cellular activities aaa_5
A7C91_10015	ENOG41065SU	Two-component system sensor kinase
A7C91_10035	ENOG4105FDK	ABC transporter
A7C91_10045	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
A7C91_10065	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
A7C91_10080	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
A7C91_10115	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
A7C91_10160	ENOG4105WMR	Protein CrcB homolog
A7C91_10165	ENOG4105KJJ	Uncharacterized ACR, COG1993
A7C91_10180	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
A7C91_10275	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
A7C91_10280	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
A7C91_10315	ENOG4108J2R	molybdopterin oxidoreductase
A7C91_10320	ENOG4105D3R	alkyl hydroperoxide reductase
A7C91_10375	ENOG4105F4P	)-transporter
A7C91_10410	ENOG4105D3R	alkyl hydroperoxide reductase
A7C91_10415	ENOG4108YYH	Nadph-dependent fmn reductase
A7C91_10430	ENOG4105JRK	feS assembly protein SufD
A7C91_10440	ENOG4105C3K	feS assembly ATPase SufC
A7C91_10445	ENOG41090A1	ferritin
A7C91_10450	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
A7C91_10455	ENOG4105D06	uba thif-type nad fad binding protein
A7C91_10460	ENOG4107Y03	Nitroreductase
A7C91_10490	ENOG4105DQU	oxidoreductase, subunit beta
A7C91_10495	ENOG4105D3R	alkyl hydroperoxide reductase
A7C91_10500	ENOG4105CNW	domain protein
A7C91_10515	ENOG4108RAC	Rubrerythrin
A7C91_10520	ENOG4105VCQ	rubredoxin
A7C91_10525	ENOG4108YZ8	Superoxide reductase
A7C91_10580	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
A7C91_10590	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
A7C91_10595	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
A7C91_10605	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
A7C91_10610	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
A7C91_10615	ENOG4105CIH	Imidazole acetol-phosphate transaminase