locus-tag	class	description
A7C91_00010	COG1353	crispr-associated protein
A7C91_00020	COG1337	RAMP superfamily
A7C91_00040	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
A7C91_00050	COG1301	dicarboxylic acid transport
A7C91_00060	COG1830	Aldolase
A7C91_00095	COG2267	carboxylic ester hydrolase activity
A7C91_00115	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
A7C91_00130	COG0455	bacterial-type flagellum organization
A7C91_00135	COG0489	protein tyrosine kinase activity
A7C91_00145	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
A7C91_00200	COG1342	Belongs to the UPF0251 family
A7C91_00205	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
A7C91_00230	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
A7C91_00260	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
A7C91_00275	COG1201	RNA secondary structure unwinding
A7C91_00280	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A7C91_00285	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A7C91_00295	COG0084	hydrolase, TatD family'
A7C91_00330	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
A7C91_00340	COG0105	UTP biosynthetic process
A7C91_00385	COG0175	sulfate reduction
A7C91_00400	COG0402	S-adenosylhomocysteine deaminase activity
A7C91_00405	COG0017	Asparaginyl-tRNA synthetase
A7C91_00420	COG4143	(ABC) transporter
A7C91_00440	COG1444	tRNA N-acetyltransferase activity
A7C91_00455	COG1268	BioY protein
A7C91_00460	COG1122	ATPase activity
A7C91_00465	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
A7C91_00490	COG1522	sequence-specific DNA binding
A7C91_00510	COG1178	ABC-type Fe3 transport system permease component
A7C91_00515	COG3842	ATPase activity
A7C91_00540	COG0126	phosphoglycerate kinase activity
A7C91_00565	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
A7C91_00595	COG0045	succinate-CoA ligase (ADP-forming) activity
A7C91_00595	COG1042	CoA-binding domain protein
A7C91_00595	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A7C91_00605	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
A7C91_00625	COG0301	tRNA thio-modification
A7C91_00680	COG1199	ATP-dependent helicase activity
A7C91_00695	COG0513	Belongs to the DEAD box helicase family
A7C91_00725	COG1979	alcohol dehydrogenase
A7C91_00735	COG1984	allophanate hydrolase subunit 2
A7C91_00740	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
A7C91_00745	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
A7C91_00780	COG0330	HflC and HflK could
A7C91_00800	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
A7C91_00815	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
A7C91_00865	COG1196	nuclear chromosome segregation
A7C91_00885	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
A7C91_00885	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
A7C91_00890	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
A7C91_00895	COG0424	maF-like protein
A7C91_00900	COG4956	integral membrane protein (PIN domain superfamily)
A7C91_00905	COG2894	cell division
A7C91_00915	COG0367	asparagine synthase
A7C91_00925	COG0297	glycogen (starch) synthase activity
A7C91_00930	COG0009	L-threonylcarbamoyladenylate synthase
A7C91_00950	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
A7C91_00955	COG0303	'Molybdopterin
A7C91_00965	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
A7C91_00980	COG1042	CoA-binding domain protein
A7C91_00980	COG0045	succinate-CoA ligase (ADP-forming) activity
A7C91_00980	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A7C91_01020	COG0482	sulfurtransferase activity
A7C91_01075	COG0071	Belongs to the small heat shock protein (HSP20) family
A7C91_01155	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
A7C91_01235	COG0560	Phosphoserine phosphatase
A7C91_01255	COG0535	radical SAM domain protein
A7C91_01260	COG1051	belongs to the nudix hydrolase family
A7C91_01260	COG1056	cytidyltransferase-related domain
A7C91_01310	COG0560	Phosphoserine phosphatase
A7C91_01315	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
A7C91_01380	COG2264	protein methyltransferase activity
A7C91_01400	COG0835	chemotaxis
A7C91_01405	COG0840	transmembrane signaling receptor activity
A7C91_01415	COG2201	protein-glutamate methylesterase activity
A7C91_01420	COG2201	protein-glutamate methylesterase activity
A7C91_01425	COG0643	Histidine kinase
A7C91_01425	COG2198	Histidine kinase
A7C91_01440	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
A7C91_01445	COG0840	transmembrane signaling receptor activity
A7C91_01495	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
A7C91_01500	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
A7C91_01520	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
A7C91_01525	COG0725	ABC transporter, periplasmic molybdate-binding protein
A7C91_01540	COG1160	GTP binding
A7C91_01545	COG0432	Pfam Uncharacterised protein family UPF0047
A7C91_01610	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
A7C91_01615	COG1435	thymidine kinase activity
A7C91_01665	COG4555	ABC transporter
A7C91_01700	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
A7C91_01700	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
A7C91_01710	COG1192	Involved in chromosome partitioning
A7C91_01715	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
A7C91_01735	COG2119	membrane
A7C91_01770	COG1404	Belongs to the peptidase S8 family
A7C91_01900	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
A7C91_01905	COG0167	dihydroorotate dehydrogenase activity
A7C91_01930	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
A7C91_01950	COG0535	radical SAM domain protein
A7C91_01985	COG0446	pyridine nucleotide-disulphide oxidoreductase
A7C91_01995	COG0501	Belongs to the peptidase M48B family
A7C91_02015	COG0446	pyridine nucleotide-disulphide oxidoreductase
A7C91_02020	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
A7C91_02035	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
A7C91_02040	COG1522	sequence-specific DNA binding
A7C91_02045	COG0693	protein deglycase activity
A7C91_02080	COG1765	OsmC-like protein
A7C91_02090	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
A7C91_02095	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
A7C91_02100	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
A7C91_02125	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
A7C91_02170	COG0123	including yeast histone deacetylase and acetoin utilization protein
A7C91_02190	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
A7C91_02230	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
A7C91_02250	COG0651	ATP synthesis coupled electron transport
A7C91_02280	COG2212	antiporter activity
A7C91_02285	COG1863	multisubunit Na H antiporter MnhE subunit
A7C91_02310	COG0493	'glutamate synthase
A7C91_02315	COG0543	2 iron, 2 sulfur cluster binding
A7C91_02355	COG0563	adenylate kinase activity
A7C91_02360	COG0428	transporter
A7C91_02375	COG1131	(ABC) transporter
A7C91_02385	COG1476	TRANSCRIPTIONal
A7C91_02425	COG0543	2 iron, 2 sulfur cluster binding
A7C91_02430	COG0493	'glutamate synthase
A7C91_02450	COG1141	Ferredoxin
A7C91_02460	COG2151	metal-sulfur cluster biosynthetic enzyme
A7C91_02485	COG1404	Belongs to the peptidase S8 family
A7C91_02495	COG0535	radical SAM domain protein
A7C91_02510	COG0501	Belongs to the peptidase M48B family
A7C91_02515	COG2131	deaminase
A7C91_02530	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
A7C91_02540	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
A7C91_02545	COG2271	Major facilitator Superfamily
A7C91_02565	COG2814	Major facilitator Superfamily
A7C91_02570	COG1446	asparaginase
A7C91_02590	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
A7C91_02630	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
A7C91_02645	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
A7C91_02650	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
A7C91_02665	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
A7C91_02680	COG2255	four-way junction helicase activity
A7C91_02685	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
A7C91_02690	COG0156	8-amino-7-oxononanoate synthase activity
A7C91_02705	COG0456	acetyltransferase
A7C91_02705	COG1214	PFAM Peptidase M22, glycoprotease
A7C91_02710	COG0433	COG0433 Predicted ATPase
A7C91_02720	COG0419	ATPase involved in DNA repair
A7C91_02720	COG0419	ATPase involved in DNA repair
A7C91_02735	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A7C91_02740	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
A7C91_02745	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
A7C91_02760	COG2078	PFAM AMMECR1 domain protein
A7C91_02760	COG3885	ferrous iron binding
A7C91_02795	COG0351	phosphomethylpyrimidine kinase
A7C91_02795	COG1992	Thiamine-phosphate synthase
A7C91_02800	COG0540	Belongs to the ATCase OTCase family
A7C91_02805	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
A7C91_02855	COG1091	dTDP-4-dehydrorhamnose reductase activity
A7C91_02895	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
A7C91_02925	COG0714	Associated with various cellular activities
A7C91_02965	COG0647	UMP catabolic process
A7C91_02975	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
A7C91_03015	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
A7C91_03045	COG2414	aldehyde ferredoxin oxidoreductase
A7C91_03055	COG0697	spore germination
A7C91_03095	COG1378	Sugar-specific transcriptional regulator TrmB
A7C91_03130	COG1234	tRNA 3'-trailer cleavage
A7C91_03135	COG1297	OPT oligopeptide transporter protein
A7C91_03145	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
A7C91_03190	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
A7C91_03230	COG0174	glutamine synthetase
A7C91_03250	COG4608	Belongs to the ABC transporter superfamily
A7C91_03255	COG0444	Belongs to the ABC transporter superfamily
A7C91_03260	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
A7C91_03265	COG0601	transmembrane transport
A7C91_03300	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
A7C91_03310	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
A7C91_03310	COG0426	domain, Protein
A7C91_03315	COG1394	ATPase activity, coupled to movement of substances
A7C91_03325	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
A7C91_03350	COG1269	ATP hydrolysis coupled proton transport
A7C91_03360	COG0569	domain protein
A7C91_03365	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
A7C91_03370	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
A7C91_03375	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
A7C91_03385	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
A7C91_03415	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
A7C91_03430	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
A7C91_03445	COG0124	histidyl-tRNA synthetase
A7C91_03470	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
A7C91_03480	COG0037	tRNA processing
A7C91_03525	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
A7C91_03535	COG2046	Belongs to the sulfate adenylyltransferase family
A7C91_03575	COG0297	glycogen (starch) synthase activity
A7C91_03580	COG1216	Glycosyl transferase, family 2
A7C91_03580	COG1442	glycosyl transferase family 8
A7C91_03605	COG0673	inositol 2-dehydrogenase activity
A7C91_03610	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
A7C91_03625	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
A7C91_03630	COG0037	tRNA processing
A7C91_03650	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
A7C91_03655	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
A7C91_03680	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
A7C91_03700	COG0714	Associated with various cellular activities
A7C91_03725	COG1047	Peptidyl-prolyl cis-trans
A7C91_03765	COG0116	Belongs to the methyltransferase superfamily
A7C91_03780	COG0179	Fumarylacetoacetate (FAA) hydrolase
A7C91_03795	COG0180	Tryptophanyl-tRNA synthetase
A7C91_03800	COG1042	CoA-binding domain protein
A7C91_03800	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A7C91_03800	COG0045	succinate-CoA ligase (ADP-forming) activity
A7C91_03805	COG0490	domain, Protein
A7C91_03805	COG0471	metal ion transport
A7C91_03810	COG0640	Transcriptional regulator
A7C91_03855	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
A7C91_03855	COG0731	radical SAM domain protein
A7C91_03875	COG0402	S-adenosylhomocysteine deaminase activity
A7C91_03890	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
A7C91_03915	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
A7C91_03980	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
A7C91_03990	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
A7C91_04000	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
A7C91_04000	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
A7C91_04060	COG0314	molybdopterin synthase activity
A7C91_04080	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
A7C91_04085	COG1522	sequence-specific DNA binding
A7C91_04095	COG0148	phosphopyruvate hydratase activity
A7C91_04110	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
A7C91_04125	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
A7C91_04130	COG0492	ferredoxin-NADP+ reductase activity
A7C91_04150	COG2255	four-way junction helicase activity
A7C91_04155	COG0301	tRNA thio-modification
A7C91_04155	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A7C91_04170	COG0650	Formate hydrogenlyase subunit 4
A7C91_04180	COG3261	NADH dehydrogenase
A7C91_04180	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
A7C91_04185	COG3260	NADH ubiquinone oxidoreductase 20
A7C91_04195	COG0651	ATP synthesis coupled electron transport
A7C91_04220	COG1320	monovalent cation:proton antiporter activity
A7C91_04225	COG2212	antiporter activity
A7C91_04230	COG1863	multisubunit Na H antiporter MnhE subunit
A7C91_04235	COG0746	molybdenum cofactor guanylyltransferase activity
A7C91_04240	COG0651	ATP synthesis coupled electron transport
A7C91_04250	COG1006	Multisubunit Na H antiporter MnhC subunit
A7C91_04255	COG2111	Na H antiporter
A7C91_04265	COG1320	monovalent cation:proton antiporter activity
A7C91_04275	COG2116	formate transmembrane transporter activity
A7C91_04285	COG3260	NADH ubiquinone oxidoreductase 20
A7C91_04290	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A7C91_04305	COG0651	ATP synthesis coupled electron transport
A7C91_04310	COG0651	ATP synthesis coupled electron transport
A7C91_04315	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
A7C91_04320	COG3383	formate dehydrogenase (NAD+) activity
A7C91_04325	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
A7C91_04340	COG3259	Nickel-dependent hydrogenase
A7C91_04345	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
A7C91_04350	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
A7C91_04375	COG0306	phosphate transporter
A7C91_04400	COG0823	Involved in the tonB-independent uptake of proteins
A7C91_04400	COG1506	peptidase
A7C91_04400	COG4946	Tricorn protease homolog
A7C91_04440	COG0681	Belongs to the peptidase S26 family
A7C91_04445	COG0095	Lipoate-protein ligase
A7C91_04490	COG0704	Plays a role in the regulation of phosphate uptake
A7C91_04495	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
A7C91_04545	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
A7C91_04575	COG0235	Class ii aldolase
A7C91_04585	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
A7C91_04620	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
A7C91_04630	COG1573	uracil-dna glycosylase
A7C91_04635	COG1757	Na H antiporter
A7C91_04645	COG1793	dna ligase
A7C91_04655	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
A7C91_04665	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
A7C91_04670	COG1522	sequence-specific DNA binding
A7C91_04755	COG1233	COG1233 Phytoene dehydrogenase and related
A7C91_04785	COG1980	fructose-bisphosphate aldolase activity
A7C91_04810	COG0589	response to stress
A7C91_04815	COG1628	Protein of unknown function DUF99
A7C91_04825	COG1254	Belongs to the acylphosphatase family
A7C91_04835	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
A7C91_04860	COG0489	protein tyrosine kinase activity
A7C91_04870	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
A7C91_04880	COG1013	pyruvate-flavodoxin oxidoreductase activity
A7C91_04885	COG0674	pyruvate-flavodoxin oxidoreductase activity
A7C91_04895	COG1013	pyruvate-flavodoxin oxidoreductase activity
A7C91_04900	COG0674	pyruvate-flavodoxin oxidoreductase activity
A7C91_04915	COG0306	phosphate transporter
A7C91_04920	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
A7C91_04935	COG0475	glutathione-regulated potassium exporter activity
A7C91_04960	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
A7C91_04965	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
A7C91_04975	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
A7C91_05020	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
A7C91_05040	COG0312	modulator of DNA gyrase
A7C91_05065	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
A7C91_05070	COG0714	Associated with various cellular activities
A7C91_05085	COG0434	BtpA family
A7C91_05105	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
A7C91_05150	COG2244	polysaccharide biosynthetic process
A7C91_05155	COG3119	arylsulfatase activity
A7C91_05195	COG1216	Glycosyl transferase, family 2
A7C91_05260	COG1120	ATPase activity
A7C91_05270	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
A7C91_05305	COG0516	GMP reductase activity
A7C91_05305	COG0517	IMP dehydrogenase activity
A7C91_05310	COG4555	ABC transporter
A7C91_05340	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
A7C91_05350	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
A7C91_05360	COG0157	Belongs to the NadC ModD family
A7C91_05380	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
A7C91_05390	COG4637	Psort location Cytoplasmic, score
A7C91_05420	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
A7C91_05425	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
A7C91_05430	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
A7C91_05435	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
A7C91_05440	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
A7C91_05445	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
A7C91_05450	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
A7C91_05455	COG0151	Belongs to the GarS family
A7C91_05470	COG0047	phosphoribosylformylglycinamidine synthase activity
A7C91_05475	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
A7C91_05485	COG0518	GMP synthase (glutamine-hydrolyzing) activity
A7C91_05485	COG0519	Catalyzes the synthesis of GMP from XMP
A7C91_05490	COG0519	Catalyzes the synthesis of GMP from XMP
A7C91_05490	COG0518	GMP synthase (glutamine-hydrolyzing) activity
A7C91_05550	COG2890	protein-(glutamine-N5) methyltransferase activity
A7C91_05580	COG0557	exoribonuclease II activity
A7C91_05645	COG2234	aminopeptidase activity
A7C91_05665	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
A7C91_05690	COG1695	Transcriptional regulator
A7C91_05705	COG0393	Putative heavy-metal-binding
A7C91_05715	COG2264	protein methyltransferase activity
A7C91_05735	COG0668	transmembrane transport
A7C91_05785	COG0218	Necessary for normal cell division and for the maintenance of normal septation
A7C91_05790	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
A7C91_05800	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
A7C91_05865	COG2252	PERMEase
A7C91_05875	COG4208	sulfate ABC transporter
A7C91_05900	COG0011	TIGRFAM Protein of
A7C91_05905	COG2078	PFAM AMMECR1 domain protein
A7C91_05910	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
A7C91_05910	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
A7C91_05955	COG1185	polyribonucleotide nucleotidyltransferase activity
A7C91_05975	COG1695	Transcriptional regulator
A7C91_05980	COG2050	protein possibly involved in aromatic compounds catabolism
A7C91_05980	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
A7C91_05990	COG1335	isochorismatase
A7C91_05995	COG0628	permease
A7C91_06015	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A7C91_06075	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
A7C91_06090	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
A7C91_06095	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
A7C91_06120	COG2239	Acts as a magnesium transporter
A7C91_06125	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
A7C91_06130	COG5016	pyruvate
A7C91_06130	COG0511	ligase activity, forming carbon-carbon bonds
A7C91_06140	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
A7C91_06150	COG0305	Participates in initiation and elongation during chromosome replication
A7C91_06150	COG1372	Participates in initiation and elongation during chromosome replication
A7C91_06170	COG0430	RNA-3'-phosphate cyclase activity
A7C91_06195	COG0543	2 iron, 2 sulfur cluster binding
A7C91_06205	COG0543	2 iron, 2 sulfur cluster binding
A7C91_06215	COG0017	Asparaginyl-tRNA synthetase
A7C91_06230	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
A7C91_06260	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
A7C91_06265	COG0088	Forms part of the polypeptide exit tunnel
A7C91_06270	COG0089	rRNA binding
A7C91_06275	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
A7C91_06280	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
A7C91_06285	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
A7C91_06290	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
A7C91_06295	COG0255	Belongs to the universal ribosomal protein uL29 family
A7C91_06300	COG0023	Translation Initiation Factor
A7C91_06310	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
A7C91_06315	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
A7C91_06330	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
A7C91_06340	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
A7C91_06345	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
A7C91_06360	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
A7C91_06365	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
A7C91_06370	COG1841	ribosomal large subunit assembly
A7C91_06375	COG0200	Binds to the 23S rRNA
A7C91_06400	COG1102	Psort location Cytoplasmic, score
A7C91_06410	COG1028	Short-chain dehydrogenase reductase Sdr
A7C91_06415	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
A7C91_06430	COG2813	Specifically methylates the guanine in position
A7C91_06440	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
A7C91_06445	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
A7C91_06470	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
A7C91_06475	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
A7C91_06495	COG0148	phosphopyruvate hydratase activity
A7C91_06500	COG0052	Belongs to the universal ribosomal protein uS2 family
A7C91_06540	COG1522	sequence-specific DNA binding
A7C91_06550	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
A7C91_06565	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
A7C91_06585	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
A7C91_06590	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
A7C91_06615	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
A7C91_06625	COG1355	regulation of microtubule-based process
A7C91_06640	COG1304	FMN binding
A7C91_06645	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
A7C91_06675	COG0495	leucyl-tRNA aminoacylation
A7C91_06680	COG2409	Drug exporters of the RND superfamily
A7C91_06710	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
A7C91_06725	COG0864	Transcriptional regulator
A7C91_06745	COG0347	Belongs to the P(II) protein family
A7C91_06755	COG0733	neurotransmitter:sodium symporter activity
A7C91_06760	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
A7C91_06770	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
A7C91_06775	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
A7C91_06790	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
A7C91_06815	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
A7C91_06820	COG0534	Mate efflux family protein
A7C91_06825	COG0574	Belongs to the PEP-utilizing enzyme family
A7C91_06825	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
A7C91_06865	COG0446	pyridine nucleotide-disulphide oxidoreductase
A7C91_06900	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
A7C91_06910	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
A7C91_06925	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
A7C91_06930	COG0409	Hydrogenase expression formation protein
A7C91_06935	COG0298	carbon dioxide binding
A7C91_06940	COG1309	transcriptional regulator
A7C91_06945	COG3383	formate dehydrogenase (NAD+) activity
A7C91_06955	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
A7C91_06960	COG0651	ATP synthesis coupled electron transport
A7C91_06965	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
A7C91_06970	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
A7C91_06970	COG3261	NADH dehydrogenase
A7C91_06975	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A7C91_06980	COG3260	NADH ubiquinone oxidoreductase 20
A7C91_06995	COG1320	monovalent cation:proton antiporter activity
A7C91_07010	COG1006	Multisubunit Na H antiporter MnhC subunit
A7C91_07020	COG0651	ATP synthesis coupled electron transport
A7C91_07030	COG0746	molybdenum cofactor guanylyltransferase activity
A7C91_07040	COG0489	protein tyrosine kinase activity
A7C91_07075	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
A7C91_07080	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
A7C91_07090	COG1234	tRNA 3'-trailer cleavage
A7C91_07105	COG1994	Peptidase M50
A7C91_07110	COG2140	Oxalate decarboxylase
A7C91_07145	COG1122	ATPase activity
A7C91_07160	COG0310	cobalt ion transport
A7C91_07175	COG1185	polyribonucleotide nucleotidyltransferase activity
A7C91_07255	COG0049	tRNA binding
A7C91_07275	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
A7C91_07280	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
A7C91_07285	COG0085	RNA polymerase activity
A7C91_07315	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
A7C91_07365	COG0579	oxidoreductase
A7C91_07375	COG0584	glycerophosphoryl diester phosphodiesterase
A7C91_07380	COG0584	glycerophosphoryl diester phosphodiesterase
A7C91_07385	COG2211	Major facilitator Superfamily
A7C91_07390	COG2271	Major facilitator Superfamily
A7C91_07395	COG1073	alpha beta
A7C91_07400	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
A7C91_07430	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
A7C91_07480	COG0081	regulation of translation
A7C91_07485	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
A7C91_07500	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
A7C91_07550	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
A7C91_07555	COG0644	oxidoreductase
A7C91_07575	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
A7C91_07585	COG1518	maintenance of DNA repeat elements
A7C91_07595	COG2002	toxin-antitoxin pair type II binding
A7C91_07605	COG1203	CRISPR-associated helicase, Cas3
A7C91_07630	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
A7C91_07630	COG0045	succinate-CoA ligase (ADP-forming) activity
A7C91_07630	COG1042	CoA-binding domain protein
A7C91_07650	COG1110	DNA topoisomerase II activity
A7C91_07685	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
A7C91_07695	COG0546	phosphoglycolate phosphatase activity
A7C91_07710	COG1418	mRNA catabolic process
A7C91_07720	COG0017	Asparaginyl-tRNA synthetase
A7C91_07735	COG0585	pseudouridine synthase activity
A7C91_07775	COG0504	CTP synthase activity
A7C91_07795	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
A7C91_07805	COG1968	undecaprenyl-diphosphatase activity
A7C91_07820	COG0516	GMP reductase activity
A7C91_07820	COG0517	IMP dehydrogenase activity
A7C91_07835	COG0024	Methionine aminopeptidase
A7C91_07840	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
A7C91_07845	COG1122	ATPase activity
A7C91_07885	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
A7C91_07900	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
A7C91_07905	COG1185	polyribonucleotide nucleotidyltransferase activity
A7C91_07950	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
A7C91_07970	COG1131	(ABC) transporter
A7C91_07980	COG0556	nucleotide-excision repair
A7C91_07985	COG0101	tRNA pseudouridine synthase activity
A7C91_07990	COG0072	phenylalanine-tRNA ligase activity
A7C91_08000	COG1063	alcohol dehydrogenase
A7C91_08005	COG2894	cell division
A7C91_08020	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
A7C91_08025	COG0252	asparaginase activity
A7C91_08055	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
A7C91_08065	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
A7C91_08090	COG0726	polysaccharide deacetylase
A7C91_08105	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
A7C91_08120	COG0038	chloride channel
A7C91_08140	COG0010	Belongs to the arginase family
A7C91_08190	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
A7C91_08200	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
A7C91_08225	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
A7C91_08230	COG0656	L-ascorbic acid biosynthetic process
A7C91_08250	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A7C91_08250	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
A7C91_08275	COG0359	binds to the 23S rRNA
A7C91_08275	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
A7C91_08325	COG0602	queuosine metabolic process
A7C91_08340	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
A7C91_08410	COG1151	hydroxylamine reductase activity
A7C91_08455	COG0649	NAD binding
A7C91_08460	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
A7C91_08470	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
A7C91_08480	COG0651	ATP synthesis coupled electron transport
A7C91_08485	COG1006	Multisubunit Na H antiporter MnhC subunit
A7C91_08490	COG2111	Na H antiporter
A7C91_08490	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
A7C91_08500	COG1320	monovalent cation:proton antiporter activity
A7C91_08505	COG2212	antiporter activity
A7C91_08510	COG1863	multisubunit Na H antiporter MnhE subunit
A7C91_08545	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
A7C91_08565	COG0018	arginyl-trna synthetase
A7C91_08570	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
A7C91_08660	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
A7C91_08660	COG0301	tRNA thio-modification
A7C91_08665	COG1836	PFAM Integral membrane protein DUF92
A7C91_08670	COG1522	sequence-specific DNA binding
A7C91_08680	COG0640	Transcriptional regulator
A7C91_08700	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
A7C91_08705	COG0396	ATPase activity
A7C91_08710	COG0719	Fe-S assembly protein
A7C91_08730	COG1941	NADH ubiquinone oxidoreductase 20 kDa subunit
A7C91_08750	COG3383	formate dehydrogenase (NAD+) activity
A7C91_08755	COG0437	4 iron, 4 sulfur cluster binding
A7C91_08765	COG0493	'glutamate synthase
A7C91_08780	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
A7C91_08790	COG1476	TRANSCRIPTIONal
A7C91_08825	COG1515	deoxyribonuclease V activity
A7C91_08835	COG1812	S-adenosylmethionine synthetase (AdoMet synthetase)
A7C91_08845	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
A7C91_08860	COG0436	Aminotransferase
A7C91_08865	COG2192	nodulation
A7C91_08875	COG0442	prolyl-tRNA aminoacylation
A7C91_08880	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
A7C91_08890	COG0730	response to heat
A7C91_08915	COG0720	synthase
A7C91_08930	COG1013	pyruvate-flavodoxin oxidoreductase activity
A7C91_08935	COG0674	pyruvate-flavodoxin oxidoreductase activity
A7C91_08935	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
A7C91_08945	COG1013	pyruvate-flavodoxin oxidoreductase activity
A7C91_08950	COG0674	pyruvate-flavodoxin oxidoreductase activity
A7C91_08950	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
A7C91_08965	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
A7C91_08995	COG1744	ABC transporter substrate-binding protein PnrA-like
A7C91_09030	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
A7C91_09035	COG0215	cysteine-tRNA ligase activity
A7C91_09055	COG1136	(ABC) transporter
A7C91_09065	COG0351	phosphomethylpyrimidine kinase
A7C91_09065	COG0352	thiamine-phosphate diphosphorylase activity
A7C91_09070	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
A7C91_09075	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
A7C91_09080	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
A7C91_09095	COG1505	serine-type exopeptidase activity
A7C91_09100	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
A7C91_09105	COG1201	RNA secondary structure unwinding
A7C91_09195	COG2096	Adenosyltransferase
A7C91_09205	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
A7C91_09210	COG1058	Belongs to the CinA family
A7C91_09210	COG1546	Belongs to the CinA family
A7C91_09215	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
A7C91_09225	COG1872	DUF167
A7C91_09235	COG0423	glycine-tRNA ligase activity
A7C91_09250	COG0534	Mate efflux family protein
A7C91_09270	COG1867	N(2),N(2)-dimethylguanosine tRNA methyltransferase
A7C91_09285	COG0006	proline dipeptidase activity
A7C91_09300	COG0482	sulfurtransferase activity
A7C91_09325	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
A7C91_09335	COG0163	prenyltransferase activity
A7C91_09360	COG0012	GTP binding
A7C91_09375	COG2078	PFAM AMMECR1 domain protein
A7C91_09380	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
A7C91_09380	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
A7C91_09410	COG1794	racemase activity, acting on amino acids and derivatives
A7C91_09415	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
A7C91_09450	COG0312	modulator of DNA gyrase
A7C91_09460	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
A7C91_09485	COG0525	valine-tRNA ligase activity
A7C91_09500	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
A7C91_09505	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
A7C91_09530	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
A7C91_09535	COG0746	molybdenum cofactor guanylyltransferase activity
A7C91_09555	COG1492	cobalamin metabolic process
A7C91_09575	COG0303	'Molybdopterin
A7C91_09600	COG1078	dGTPase activity
A7C91_09625	COG1899	peptidyl-lysine modification to peptidyl-hypusine
A7C91_09630	COG0493	'glutamate synthase
A7C91_09635	COG1028	Short-chain dehydrogenase reductase Sdr
A7C91_09655	COG0459	protein refolding
A7C91_09695	COG0315	cyclic pyranopterin monophosphate synthase activity
A7C91_09710	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
A7C91_09710	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
A7C91_09720	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
A7C91_09735	COG1216	Glycosyl transferase, family 2
A7C91_09765	COG1739	Uncharacterized protein family UPF0029
A7C91_09780	COG1121	(ABC) transporter
A7C91_09800	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
A7C91_09860	COG2403	cyclic 2,3-diphosphoglycerate synthetase activity
A7C91_09880	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
A7C91_09885	COG2414	aldehyde ferredoxin oxidoreductase
A7C91_09920	COG0051	transcription antitermination factor activity, RNA binding
A7C91_09925	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
A7C91_09935	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
A7C91_09980	COG1469	GTP cyclohydrolase I activity
A7C91_09990	COG1401	restriction endodeoxyribonuclease activity
A7C91_10015	COG2205	protein histidine kinase activity
A7C91_10035	COG1121	(ABC) transporter
A7C91_10045	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
A7C91_10065	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
A7C91_10080	COG2226	methyltransferase
A7C91_10085	COG0011	TIGRFAM Protein of
A7C91_10115	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
A7C91_10160	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
A7C91_10165	COG1993	acr, cog1993
A7C91_10185	COG1794	racemase activity, acting on amino acids and derivatives
A7C91_10195	COG0312	modulator of DNA gyrase
A7C91_10200	COG0312	modulator of DNA gyrase
A7C91_10275	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
A7C91_10280	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
A7C91_10315	COG0243	molybdopterin cofactor binding
A7C91_10320	COG0450	alkyl hydroperoxide reductase
A7C91_10375	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
A7C91_10390	COG2217	Heavy metal translocating P-type atpase
A7C91_10410	COG0450	alkyl hydroperoxide reductase
A7C91_10430	COG0719	Fe-S assembly protein
A7C91_10440	COG0396	ATPase activity
A7C91_10445	COG1528	Iron-storage protein
A7C91_10450	COG0301	tRNA thio-modification
A7C91_10455	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
A7C91_10460	COG0778	Nitroreductase
A7C91_10490	COG1013	pyruvate-flavodoxin oxidoreductase activity
A7C91_10495	COG0450	alkyl hydroperoxide reductase
A7C91_10500	COG0426	domain, Protein
A7C91_10515	COG1592	Rubrerythrin
A7C91_10520	COG1773	rubredoxin
A7C91_10525	COG2033	superoxide reductase activity
A7C91_10580	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
A7C91_10590	COG0131	Imidazoleglycerol-phosphate dehydratase
A7C91_10595	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
A7C91_10605	COG0107	imidazoleglycerol-phosphate synthase activity
A7C91_10610	COG0140	phosphoribosyl-ATP diphosphatase activity
A7C91_10610	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
A7C91_10615	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily