locus-tag	class	description
A3L09_00015	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
A3L09_00025	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
A3L09_00045	ENOG4105DZ0	fad dependent oxidoreductase
A3L09_00050	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
A3L09_00055	ENOG4107RWR	Sodium hydrogen exchanger
A3L09_00060	ENOG4107RWR	Sodium hydrogen exchanger
A3L09_00065	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
A3L09_00070	ENOG4105CUT	histidyl-tRNA synthetase
A3L09_00110	ENOG4105VFR	signal peptidase
A3L09_00120	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
A3L09_00160	ENOG4105E66	phosphoriboisomerase A
A3L09_00170	ENOG4107QMS	site-determining protein
A3L09_00200	ENOG4108IGT	Dipeptidase
A3L09_00240	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
A3L09_00270	ENOG4107QXV	Phosphate transporter
A3L09_00280	ENOG4105EWK	phytoene
A3L09_00290	ENOG4107NFR	Fructose-1,6-bisphosphatase
A3L09_00315	ENOG4105CDJ	oxidoreductase FAD NAD(P)-binding domain protein
A3L09_00320	ENOG4105BZ8	glutamate synthase
A3L09_00345	ENOG41084T3	4fe-4S ferredoxin iron-sulfur binding domain-containing protein
A3L09_00350	ENOG4105VG1	fes assembly suf system protein
A3L09_00360	ENOG4108JVH	Protein of unknown function DUF43
A3L09_00370	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
A3L09_00390	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
A3L09_00400	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
A3L09_00415	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
A3L09_00420	ENOG4105DA5	(ABC) transporter
A3L09_00480	ENOG4107QX8	SPFH domain, Band 7 family protein
A3L09_00490	ENOG4105DSM	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein (By similarity)
A3L09_00500	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
A3L09_00505	ENOG4108VVK	transcriptional Regulator, AsnC
A3L09_00510	ENOG4105CJ1	ABC, transporter
A3L09_00545	ENOG4108VA3	3-hexulose-6-phosphate synthase
A3L09_00550	ENOG4107XMU	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
A3L09_00560	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
A3L09_00585	ENOG4105C5S	asparaginyl-tRNA synthetase
A3L09_00600	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
A3L09_00610	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
A3L09_00655	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
A3L09_00665	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
A3L09_00700	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
A3L09_00705	ENOG4105C5I	Dehydrogenase
A3L09_00755	ENOG4107PBV	potassium channel
A3L09_00765	ENOG4105CYV	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures (By similarity)
A3L09_00780	ENOG4105CB1	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
A3L09_00790	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
A3L09_00800	ENOG4108RVA	ribokinase
A3L09_00830	ENOG410704R	Produces ATP from ADP in the presence of a proton gradient across the membrane
A3L09_00835	ENOG4108JIQ	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit (By similarity)
A3L09_00855	ENOG4105C8Q	Methyl-accepting chemotaxis
A3L09_00860	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
A3L09_00930	ENOG4105CJ1	ABC, transporter
A3L09_00975	ENOG4108VVK	transcriptional Regulator, AsnC
A3L09_01000	ENOG4108ZAF	Molybdopterin
A3L09_01010	ENOG4105D06	uba thif-type nad fad binding protein
A3L09_01015	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
A3L09_01030	ENOG4108JPW	Aminotransferase
A3L09_01035	ENOG4105C3M	thioredoxin reductase
A3L09_01045	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
A3L09_01065	ENOG4105CTD	carboxy-peptidase
A3L09_01085	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
A3L09_01105	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
A3L09_01140	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
A3L09_01145	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
A3L09_01150	ENOG4105ERH	Fumarylacetoacetate hydrolase
A3L09_01170	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
A3L09_01175	ENOG4105C4K	Nad synthetase
A3L09_01180	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
A3L09_01205	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
A3L09_01220	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
A3L09_01245	ENOG4107W7X	Aldolase
A3L09_01255	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
A3L09_01270	ENOG4107XF7	NGG1p interacting factor 3 protein, NIF3
A3L09_01285	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
A3L09_01295	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
A3L09_01300	ENOG4105CJ3	phosphate transporter
A3L09_01315	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
A3L09_01320	ENOG4105DDK	oxidoreductase, beta subunit
A3L09_01325	ENOG4107XUH	ferredoxin (flavodoxin) oxidoreductase
A3L09_01330	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
A3L09_01335	ENOG4105DDK	oxidoreductase, beta subunit
A3L09_01345	ENOG4105QAX	Iron-sulfur
A3L09_01350	ENOG4105BZ8	glutamate synthase
A3L09_01355	ENOG4105WGB	oxidoreductase, delta subunit
A3L09_01360	ENOG4105CJG	carbon-monoxide dehydrogenase catalytic subunit
A3L09_01365	ENOG4105QAX	Iron-sulfur
A3L09_01370	ENOG41080XS	Cobyrinic acid ac-diamide synthase
A3L09_01375	ENOG4108ESE	uses NADH to detoxify nitric oxide (NO), protecting several 4Fe-4S NO-sensitive enzymes. Has at least 2 reductase partners, only one of which (NorW, flavorubredoxin reductase) has been identified. NO probably binds to the di-iron center
A3L09_01390	ENOG41090A1	ferritin
A3L09_01400	ENOG4107UX3	phosphatidylethanolamine N-methyltransferase
A3L09_01405	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
A3L09_01420	ENOG4106FTQ	Taurine ABC transporter, periplasmic
A3L09_01430	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
A3L09_01435	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
A3L09_01445	ENOG4108I9K	permease protein
A3L09_01465	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
A3L09_01470	ENOG4105C4M	(Ubiquinol oxidase) subunit I
A3L09_01490	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
A3L09_01505	ENOG4105EAH	synthase
A3L09_01510	ENOG4105D65	subunit l
A3L09_01515	ENOG4108JPZ	Monovalent cation H antiporter subunit D
A3L09_01520	ENOG410684G	monovalent cation H antiporter subunit F
A3L09_01525	ENOG4105KJM	monovalent cation h antiporter subunit g
A3L09_01540	ENOG4105MKQ	Monovalent cation H antiporter subunit C
A3L09_01545	ENOG4105SC1	monovalent cation H antiporter subunit E
A3L09_01550	ENOG4108JPZ	Monovalent cation H antiporter subunit D
A3L09_01565	ENOG4105EHG	Permease protein
A3L09_01570	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
A3L09_01575	ENOG4105D1F	ATP-binding protein
A3L09_01595	ENOG4105D1H	recombination factor protein RarA
A3L09_01610	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
A3L09_01620	ENOG41066UM	arsR family transcriptional regulator
A3L09_01630	ENOG41082SX	arsR family transcriptional regulator
A3L09_01650	ENOG41080TA	Multiple resistance and ph regulation protein f
A3L09_01655	ENOG4105KJM	monovalent cation h antiporter subunit g
A3L09_01675	ENOG4108ZE9	Monovalent cation H antiporter subunit C
A3L09_01680	ENOG4108JPZ	Monovalent cation H antiporter subunit D
A3L09_01690	ENOG4105C47	NADH ubiquinone oxidoreductase 20 kda subunit
A3L09_01695	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
A3L09_01700	ENOG4108HM5	NADH-ubiquinone oxidoreductase chain 49kDa
A3L09_01705	ENOG4107TDF	Formate hydrogenlyase subunit 4
A3L09_01735	ENOG4108KN7	Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity)
A3L09_01775	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
A3L09_01780	ENOG4105EHU	Circadian clock protein KaiC
A3L09_01785	ENOG4105DZP	Membrane-associated zinc metalloprotease
A3L09_01790	ENOG4107T8Q	Glycosyl transferase (Group 1
A3L09_01800	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
A3L09_01805	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
A3L09_01815	ENOG4106WTF	Glycosyl transferase, family 2
A3L09_01840	ENOG4105CMR	udp-glucose 4-epimerase
A3L09_01850	ENOG41076HS	cation diffusion facilitator family transporter
A3L09_01860	ENOG4107RWR	Sodium hydrogen exchanger
A3L09_01880	ENOG4105C6W	4-alpha-glucanotransferase (EC 2.4.1.25)
A3L09_01890	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
A3L09_01900	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
A3L09_01975	ENOG4107R3E	Citrate transporter
A3L09_01990	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
A3L09_02040	ENOG4105D6M	Phosphoglucomutase Phosphomannomutase
A3L09_02075	ENOG4108R9M	Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity)
A3L09_02080	ENOG4105CXT	aspartate transcarbamylase
A3L09_02085	ENOG4107ZCS	Phosphomethylpyrimidine kinase
A3L09_02115	ENOG4108IYI	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
A3L09_02130	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
A3L09_02135	ENOG4105EVI	UPF0374 protein
A3L09_02145	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
A3L09_02155	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
A3L09_02160	ENOG4105D1H	recombination factor protein RarA
A3L09_02170	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
A3L09_02190	ENOG4105EHG	Permease protein
A3L09_02195	ENOG4105E0A	ABC, transporter
A3L09_02210	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
A3L09_02250	ENOG4105DK7	lysyl-tRNA synthetase
A3L09_02255	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
A3L09_02280	ENOG41083IP	HIT family
A3L09_02300	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
A3L09_02305	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
A3L09_02310	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
A3L09_02340	ENOG4105C2X	Arabinose 5-phosphate isomerase
A3L09_02345	ENOG4105D9Q	decarboxylase (Beta subunit)
A3L09_02350	ENOG4107QSA	Oxaloacetate decarboxylase
A3L09_02360	ENOG4105D8K	carboxyl transferase
A3L09_02370	ENOG4105CDU	Replicative dna helicase
A3L09_02395	ENOG4105CKX	Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP
A3L09_02410	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
A3L09_02450	ENOG4105C5S	asparaginyl-tRNA synthetase
A3L09_02465	ENOG4105C5R	Aminotransferase
A3L09_02470	ENOG4108JQ7	(ABC) transporter
A3L09_02475	ENOG4105C3U	ABC transporter
A3L09_02480	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
A3L09_02485	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
A3L09_02535	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
A3L09_02545	ENOG41080UE	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
A3L09_02550	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
A3L09_02555	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
A3L09_02565	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
A3L09_02570	ENOG41082SA	50s ribosomal protein l29
A3L09_02575	ENOG4108ZJT	translation initiation factor, Sui1
A3L09_02585	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
A3L09_02590	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
A3L09_02595	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
A3L09_02605	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
A3L09_02615	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
A3L09_02620	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
A3L09_02635	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
A3L09_02640	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
A3L09_02645	ENOG4105VPB	50S ribosomal protein L30
A3L09_02650	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
A3L09_02675	ENOG4108Z4J	Cytidine monophosphate kinase
A3L09_02685	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
A3L09_02700	ENOG4107Y49	methyltransferase
A3L09_02710	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
A3L09_02715	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
A3L09_02720	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
A3L09_02740	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
A3L09_02745	ENOG4108UJD	30S ribosomal protein S9
A3L09_02765	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
A3L09_02770	ENOG4105CE9	30S ribosomal protein S2
A3L09_02815	ENOG4105CB1	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
A3L09_02830	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
A3L09_02855	ENOG4108YXU	transcriptional regulator AsnC family
A3L09_02865	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
A3L09_02875	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
A3L09_02890	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
A3L09_02900	ENOG4105CAQ	asparagine synthetase
A3L09_02915	ENOG4105CTP	PilT protein domain protein
A3L09_02920	ENOG4108Z03	MAF-like protein
A3L09_02925	ENOG4105DCG	PHP domain protein
A3L09_02930	ENOG4105D5P	Methylmalonyl-coA mutase
A3L09_02960	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
A3L09_02970	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
A3L09_02990	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
A3L09_03010	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
A3L09_03020	ENOG4105WE2	aldehyde ferredoxin oxidoreductase
A3L09_03045	ENOG4105C1J	atp-dependent rna helicase
A3L09_03060	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
A3L09_03070	ENOG4105C0M	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity)
A3L09_03075	ENOG4107R76	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
A3L09_03085	ENOG4105CX6	glutaminyL-tRNA synthetase
A3L09_03125	ENOG4105CN5	Metallo-Beta-Lactamase
A3L09_03130	ENOG4105EAH	synthase
A3L09_03150	ENOG4105C8T	Leucyl-tRNA synthetase
A3L09_03190	ENOG4105CHM	Aminotransferase
A3L09_03205	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
A3L09_03210	ENOG4107QJE	Chromosome Partitioning Protein
A3L09_03220	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
A3L09_03225	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
A3L09_03230	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
A3L09_03245	ENOG4108Y5D	Inherit from COG: cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
A3L09_03300	ENOG4105QAX	Iron-sulfur
A3L09_03315	ENOG4105CJ1	ABC, transporter
A3L09_03375	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
A3L09_03380	ENOG4105DIW	FeS assembly protein SUFB
A3L09_03385	ENOG4108IUZ	ABC transporter
A3L09_03405	ENOG4105WMM	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
A3L09_03425	ENOG41083NF	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
A3L09_03430	ENOG4105WRB	Hydrogenase assembly chaperone hypC hupF
A3L09_03435	ENOG4105CQS	hydrogenase expression formation protein HypD
A3L09_03455	ENOG4105C45	hydrogenase expression formation protein (HypE)
A3L09_03480	ENOG4108JPZ	Monovalent cation H antiporter subunit D
A3L09_03505	ENOG4105KJM	monovalent cation h antiporter subunit g
A3L09_03510	ENOG4105W4C	monovalent cation H antiporter subunit F
A3L09_03515	ENOG4105SC1	monovalent cation H antiporter subunit E
A3L09_03545	ENOG4106UJV	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
A3L09_03550	ENOG4105WE2	aldehyde ferredoxin oxidoreductase
A3L09_03555	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
A3L09_03580	ENOG4105D82	Glutamate dehydrogenase
A3L09_03595	ENOG41067MG	lrgb family
A3L09_03600	ENOG4105VAW	lrga family
A3L09_03610	ENOG4105C8Q	Methyl-accepting chemotaxis
A3L09_03620	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
A3L09_03630	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
A3L09_03635	ENOG4107S6Z	Na H antiporter
A3L09_03650	ENOG4108JEB	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
A3L09_03665	ENOG4105VKD	bioY protein
A3L09_03670	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
A3L09_03675	ENOG4108JJB	ABC transporter
A3L09_03725	ENOG4108JU3	Alkyl hydroperoxide reductase
A3L09_03735	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
A3L09_03740	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
A3L09_03770	ENOG4105CJ1	ABC, transporter
A3L09_03775	ENOG4107RGW	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
A3L09_03810	ENOG4106SMU	thiamine transporter membrane protein
A3L09_03815	ENOG4108IJ6	ABC transporter
A3L09_03820	ENOG4105DP9	ABC transporter
A3L09_03825	ENOG4105C8J	)-transporter
A3L09_03835	ENOG4108YZA	Nitrogen regulatory protein pii
A3L09_03840	ENOG4107RFW	hydrolase family 57
A3L09_03855	ENOG4105DEF	Extracellular solute-binding protein, family 5
A3L09_03860	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
A3L09_03865	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
A3L09_03875	ENOG4108JQ7	(ABC) transporter
A3L09_03885	ENOG4107SA6	carbon-phosphorus lyase complex accessory protein
A3L09_03895	ENOG4108TVJ	Nitroreductase
A3L09_03905	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
A3L09_03980	ENOG4108R6G	acetyltransferase
A3L09_03990	ENOG4105BZ1	(ABC) transporter
A3L09_03995	ENOG4105BZ1	(ABC) transporter
A3L09_04050	ENOG4105CB5	ATP-dependent DNA helicase recG
A3L09_04085	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
A3L09_04095	ENOG4108RCS	geranylgeranylglyceryl phosphate synthase
A3L09_04120	ENOG4105CH2	amidohydrolase
A3L09_04135	ENOG4107R7A	Allophanate hydrolase subunit 2
A3L09_04140	ENOG4105P4J	Allophanate hydrolase, subunit 1
A3L09_04145	ENOG4105E7W	lamb ycsf family protein
A3L09_04155	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
A3L09_04160	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
A3L09_04230	ENOG4105CD5	CoA-binding domain protein
A3L09_04250	ENOG4105WE2	aldehyde ferredoxin oxidoreductase
A3L09_04255	ENOG4105CEV	competence damage-inducible protein
A3L09_04270	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
A3L09_04275	ENOG4105VXP	Protein of unknown function DUF86
A3L09_04285	ENOG41074MP	UPF0103 Mediator of ErbB2-driven cell motility-containing protein
A3L09_04290	ENOG4107R5I	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
A3L09_04295	ENOG4108I5U	Uridine phosphorylase
A3L09_04310	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
A3L09_04315	ENOG4105KPK	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation (By similarity)
A3L09_04320	ENOG4105CY0	Metallo-Beta-Lactamase
A3L09_04330	ENOG4107QIM	DNA ligase
A3L09_04350	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
A3L09_04360	ENOG4107QRT	dEAD DEAH box helicase
A3L09_04365	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
A3L09_04380	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
A3L09_04390	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
A3L09_04405	ENOG4105C83	adenylosuccinate lyase
A3L09_04415	ENOG4105C8N	cysteinyl-tRNA synthetase
A3L09_04435	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
A3L09_04440	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
A3L09_04510	ENOG4107YTP	response regulator receiver protein
A3L09_04515	ENOG4105CBS	Chea signal transduction histidine kinase
A3L09_04555	ENOG4107VWA	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation (By similarity)
A3L09_04560	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
A3L09_04565	ENOG4108R96	Methyltransferase, YaeB family
A3L09_04570	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
A3L09_04575	ENOG4105DER	m42 family
A3L09_04585	ENOG4105EYF	MMPL domain protein
A3L09_04615	ENOG4108WBT	adenosyltransferase
A3L09_04655	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
A3L09_04665	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
A3L09_04680	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
A3L09_04685	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
A3L09_04705	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
A3L09_04710	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
A3L09_04745	ENOG4105UQX	Mate efflux family protein
A3L09_04750	ENOG4105UQX	Mate efflux family protein
A3L09_04765	ENOG4105KNA	-acetyltransferase
A3L09_04800	ENOG4105MRR	Transcriptional regulator (By similarity)
A3L09_04815	ENOG4105D0M	Protease HtpX homolog
A3L09_04820	ENOG4108UK2	deaminase
A3L09_04830	ENOG4107XGZ	Hydrolase
A3L09_04845	ENOG4107R7Y	intracellular protease Pfpi family
A3L09_04860	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
A3L09_04895	ENOG4105K8R	UPF0145 protein
A3L09_04955	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
A3L09_04960	ENOG4108UKZ	OsmC family
A3L09_04975	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
A3L09_04985	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
A3L09_05000	ENOG4105E4P	ATPase (AAA
A3L09_05025	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
A3L09_05030	ENOG4105C2X	Arabinose 5-phosphate isomerase
A3L09_05065	ENOG4108JJB	ABC transporter
A3L09_05100	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
A3L09_05105	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
A3L09_05135	ENOG4105C5X	domain protein
A3L09_05150	ENOG4105F8V	Hydrolase, tatD family
A3L09_05165	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
A3L09_05190	ENOG4107WZZ	SMC domain protein
A3L09_05190	ENOG4107WZZ	SMC domain protein
A3L09_05235	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
A3L09_05240	ENOG4105VXP	Protein of unknown function DUF86
A3L09_05260	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
A3L09_05265	ENOG410825M	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
A3L09_05275	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
A3L09_05325	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
A3L09_05335	ENOG4105DIH	basic membrane
A3L09_05340	ENOG4108JQ9	ABC transporter
A3L09_05345	ENOG4105UIB	(ABC) transporter
A3L09_05370	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
A3L09_05385	ENOG4105D07	Signal peptide peptidase, SppA
A3L09_05395	ENOG4105F4G	Membrane
A3L09_05400	ENOG4105EEI	dihydropteroate synthase
A3L09_05430	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
A3L09_05435	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
A3L09_05440	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
A3L09_05450	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
A3L09_05465	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
A3L09_05500	ENOG4108J2R	molybdopterin oxidoreductase
A3L09_05595	ENOG4107WTJ	Methyl-accepting chemotaxis sensory transducer
A3L09_05600	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
A3L09_05625	ENOG4105CQ2	DNA polymerase
A3L09_05635	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
A3L09_05645	ENOG4105NBF	ammecr1 domain protein
A3L09_05680	ENOG4107SHJ	sulfite reductase subunit b
A3L09_05720	ENOG4107QIZ	NADH dehydrogenase
A3L09_05735	ENOG4105DF0	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity)
A3L09_05745	ENOG4105DPX	Hydrogenase, large subunit
A3L09_05750	ENOG4105VUN	Transcriptional regulator
A3L09_05760	ENOG4105HDK	L-asparaginase
A3L09_05775	ENOG4105EPU	Molybdenum cofactor synthesis domain protein
A3L09_05785	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
A3L09_05795	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
A3L09_05800	ENOG4105E0C	molybdate abc transporter
A3L09_05810	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
A3L09_05820	ENOG4105UQX	Mate efflux family protein
A3L09_05840	ENOG41061GT	Aldolase
A3L09_05845	ENOG4105CK2	sodium dicarboxylate symporter
A3L09_05850	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
A3L09_05860	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
A3L09_05870	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
A3L09_05875	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
A3L09_05890	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
A3L09_05920	ENOG4108JU3	Alkyl hydroperoxide reductase
A3L09_05930	ENOG4108H5C	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
A3L09_05935	ENOG4105ZHF	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
A3L09_05960	ENOG4105CB5	ATP-dependent DNA helicase recG
A3L09_05985	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
A3L09_06025	ENOG4105EAC	phosphoserine phosphatase
A3L09_06040	ENOG4105IIU	Aminopeptidase
A3L09_06055	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
A3L09_06080	ENOG4105CK7	Sodium proline symporter
A3L09_06155	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
A3L09_06160	ENOG4105C8Q	Methyl-accepting chemotaxis
A3L09_06175	ENOG4105CBS	Chea signal transduction histidine kinase
A3L09_06180	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
A3L09_06185	ENOG4107YTP	response regulator receiver protein
A3L09_06190	ENOG4105BZU	Histidine kinase
A3L09_06200	ENOG4108V3W	Chemotaxis protein, CheW
A3L09_06235	ENOG4107RWR	Sodium hydrogen exchanger
A3L09_06265	ENOG4105F4P	)-transporter
A3L09_06275	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
A3L09_06280	ENOG4105CHR	reductase
A3L09_06290	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
A3L09_06300	ENOG4105N80	Ferric uptake regulator, Fur family
A3L09_06320	ENOG4105D64	Mechanosensitive ion channel
A3L09_06335	ENOG4108DNI	pyridine nucleotide-disulfide oxidoreductase
A3L09_06340	ENOG4105D3R	alkyl hydroperoxide reductase
A3L09_06345	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
A3L09_06350	ENOG4108R6K	riboflavin synthase, subunit alpha
A3L09_06355	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
A3L09_06360	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
A3L09_06370	ENOG4105CK7	Sodium proline symporter
A3L09_06385	ENOG4105C8V	SAICAR synthetase
A3L09_06395	ENOG4105IQJ	Involved in biosynthesis of the thiamine precursor thiazole (By similarity)
A3L09_06400	ENOG4105DWF	phosphomethylpyrimidine kinase
A3L09_06420	ENOG4105CHR	reductase
A3L09_06425	ENOG4108V1U	phospholipid-binding protein
A3L09_06430	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
A3L09_06440	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
A3L09_06480	ENOG4105E4P	ATPase (AAA
A3L09_06505	ENOG4105D7N	magnesium and cobalt transport protein CorA
A3L09_06520	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
A3L09_06550	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
A3L09_06555	ENOG4105DQU	oxidoreductase, subunit beta
A3L09_06575	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
A3L09_06580	ENOG4105DQU	oxidoreductase, subunit beta
A3L09_06625	ENOG41066FR	extracellular solute-binding protein
A3L09_06640	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
A3L09_06655	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
A3L09_06680	ENOG41065SU	Two-component system sensor kinase
A3L09_06685	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
A3L09_06725	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
A3L09_06735	ENOG4105D44	asparaginase
A3L09_06745	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
A3L09_06765	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
A3L09_06775	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
A3L09_06785	ENOG4105ECY	inositol monophosphatase
A3L09_06795	ENOG4107QW4	alcohol dehydrogenase
A3L09_06805	ENOG4105DCI	Phosphohydrolase
A3L09_06810	ENOG4105CHM	Aminotransferase
A3L09_06815	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
A3L09_06820	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
A3L09_06835	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
A3L09_06845	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
A3L09_06855	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
A3L09_06870	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
A3L09_06880	ENOG4105D22	carbon starvation protein
A3L09_06895	ENOG4105D0U	Arsenite-activated ATPase (ArsA)
A3L09_06910	ENOG4105E5G	Alpha beta hydrolase fold
A3L09_06940	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
A3L09_06950	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
A3L09_06985	ENOG4105EHU	Circadian clock protein KaiC
A3L09_06990	ENOG4108YZ8	Superoxide reductase
A3L09_06995	ENOG4105VCQ	rubredoxin
A3L09_07000	ENOG4108RAC	Rubrerythrin
A3L09_07015	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
A3L09_07030	ENOG4105E0R	Deoxyhypusine synthase
A3L09_07040	ENOG4108IUW	ABC transporter
A3L09_07050	ENOG4105BZ8	glutamate synthase
A3L09_07055	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
A3L09_07060	ENOG4105D0M	Protease HtpX homolog
A3L09_07070	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
A3L09_07075	ENOG4108V5V	Serine Threonine protein kinase
A3L09_07090	ENOG4105C22	threonyL-tRNA synthetase
A3L09_07095	ENOG4105D64	Mechanosensitive ion channel
A3L09_07105	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
A3L09_07150	ENOG4105CD5	CoA-binding domain protein
A3L09_07160	ENOG4105EM7	Selenocysteine-specific translation elongation factor
A3L09_07195	ENOG4105CSM	endonuclease III
A3L09_07205	ENOG4105D9P	serine threonine protein kinase
A3L09_07235	ENOG4105SFS	phosphoesterase RecJ domain protein
A3L09_07290	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
A3L09_07310	ENOG4105DT1	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate
A3L09_07320	ENOG4105DCI	Phosphohydrolase
A3L09_07330	ENOG4105BZA	Phosphoglycerate kinase
A3L09_07335	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
A3L09_07365	ENOG4105VZ9	UPF0235 protein
A3L09_07375	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
A3L09_07385	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
A3L09_07395	ENOG4105KJJ	Uncharacterized ACR, COG1993
A3L09_07400	ENOG4105WMR	Protein CrcB homolog
A3L09_07445	ENOG4106K5Q	Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication (By similarity)
A3L09_07485	ENOG4107Y70	Heat shock protein
A3L09_07515	ENOG4108I5C	dEAD DEAH box helicase
A3L09_07525	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
A3L09_07550	ENOG4108RWI	nicotinamidase
A3L09_07605	ENOG4105VZ8	Transcriptional regulator
A3L09_07610	ENOG4105CJ1	ABC, transporter
A3L09_07685	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
A3L09_07695	ENOG4105C75	arginyL-tRNA synthetase
A3L09_07710	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
A3L09_07720	ENOG4105SC1	monovalent cation H antiporter subunit E
A3L09_07725	ENOG410684G	monovalent cation H antiporter subunit F
A3L09_07730	ENOG4105KJM	monovalent cation h antiporter subunit g
A3L09_07740	ENOG4105D65	subunit l
A3L09_07750	ENOG4108JPZ	Monovalent cation H antiporter subunit D
A3L09_07755	ENOG4108JPZ	Monovalent cation H antiporter subunit D
A3L09_07765	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
A3L09_07770	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
A3L09_07775	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
A3L09_07790	ENOG4108JPW	Aminotransferase
A3L09_07795	ENOG4108ZRZ	Transcriptional regulator (AsnC family)
A3L09_07810	ENOG4108Z0R	Transferase
A3L09_07815	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
A3L09_07855	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
A3L09_07860	ENOG4105CPQ	Dehydrogenase
A3L09_07880	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
A3L09_07905	ENOG41087GE	Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity)
A3L09_07915	ENOG4105DBV	ornithine carbamoyltransferase
A3L09_07925	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
A3L09_07945	ENOG4108K3F	N(2),N(2)-dimethylguanosine tRNA methyltransferase
A3L09_07965	ENOG4105C3G	gtp-binding protein
A3L09_07980	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
A3L09_08000	ENOG4105CE1	Ferrous iron transport protein b
A3L09_08015	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
A3L09_08045	ENOG4105DC7	peptidase M24
A3L09_08065	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
A3L09_08070	ENOG4105CC5	ABC transporter
A3L09_08075	ENOG4105FDK	ABC transporter
A3L09_08085	ENOG4107G87	m6 family metalloprotease domain protein
A3L09_08090	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
A3L09_08105	ENOG4108Z4T	Peptidase M50
A3L09_08110	ENOG4108Y83	glucose-6-phosphate isomerase
A3L09_08125	ENOG4105CHM	Aminotransferase
A3L09_08145	ENOG4105CND	Glycosyl transferase, family 2
A3L09_08160	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
A3L09_08165	ENOG4105HDK	L-asparaginase
A3L09_08175	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
A3L09_08220	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
A3L09_08225	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
A3L09_08235	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
A3L09_08255	ENOG4105BZ8	glutamate synthase
A3L09_08260	ENOG4105CDJ	oxidoreductase FAD NAD(P)-binding domain protein
A3L09_08290	ENOG4105DEF	Extracellular solute-binding protein, family 5
A3L09_08295	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
A3L09_08300	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
A3L09_08310	ENOG4108JQ7	(ABC) transporter
A3L09_08340	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
A3L09_08360	ENOG4105CN9	Peptidase m42 family protein
A3L09_08385	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
A3L09_08390	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
A3L09_08400	ENOG4105C2X	Arabinose 5-phosphate isomerase
A3L09_08410	ENOG4105E3H	phosphoglycerate mutase
A3L09_08415	ENOG4105CV8	reductase
A3L09_08450	ENOG4105CD5	CoA-binding domain protein
A3L09_08475	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
A3L09_08490	ENOG4107QNG	Phosphoribosylglycinamide synthetase
A3L09_08510	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
A3L09_08515	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
A3L09_08520	ENOG4108JIU	phosphoribosylformylglycinamidine synthase ii
A3L09_08535	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
A3L09_08540	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
A3L09_08555	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
A3L09_08620	ENOG4108RMN	UPF0128 protein
A3L09_08625	ENOG4105D1Z	hydroxypyruvate reductase
A3L09_08650	ENOG4105K4P	CoA-binding domain protein
A3L09_08680	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
A3L09_08690	ENOG4105DVT	helicase
A3L09_08700	ENOG4105CN9	Peptidase m42 family protein
A3L09_08710	ENOG4105PW4	Sugar fermentation stimulation protein homolog
A3L09_08735	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
A3L09_08750	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
A3L09_08785	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
A3L09_08790	ENOG4105C5S	asparaginyl-tRNA synthetase
A3L09_08830	ENOG4105ECW	sulfate abc transporter
A3L09_08835	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
A3L09_08870	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
A3L09_08885	ENOG4107V9E	glucose-1-phosphate thymidylyltransferase
A3L09_08905	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
A3L09_08910	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
A3L09_08915	ENOG4105C8V	SAICAR synthetase
A3L09_08935	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
A3L09_08940	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
A3L09_08945	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
A3L09_08960	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
A3L09_08975	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
A3L09_08980	ENOG4108JQ7	(ABC) transporter
A3L09_08985	ENOG4105C3U	ABC transporter
A3L09_08995	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
A3L09_09035	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
A3L09_09045	ENOG41088YS	Glycosyl transferase (Group 1
A3L09_09050	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
A3L09_09060	ENOG4107T3P	ABC, transporter
A3L09_09070	ENOG4108NGU	Transcriptional regulator
A3L09_09080	ENOG4107FKK	extracellular solute-binding protein family 1
A3L09_09085	ENOG4105D56	permease protein
A3L09_09090	ENOG4105EG2	ABC transporter, permease
A3L09_09110	ENOG4105D6M	Phosphoglucomutase Phosphomannomutase
A3L09_09115	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
A3L09_09120	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
A3L09_09135	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
A3L09_09155	ENOG4108IJ6	ABC transporter
A3L09_09160	ENOG4105DR4	Methyltransferase
A3L09_09185	ENOG4105EHU	Circadian clock protein KaiC
A3L09_09200	ENOG4108IYU	L-aspartate oxidase
A3L09_09215	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
A3L09_09225	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
A3L09_09245	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
A3L09_09275	ENOG4105DZH	s-adenosylmethionine synthetase (EC 2.5.1.6)
A3L09_09280	ENOG4107QRT	dEAD DEAH box helicase
A3L09_09280	ENOG4107QRT	dEAD DEAH box helicase
A3L09_09330	ENOG4105VYW	UPF0251 protein
A3L09_09335	ENOG4107R21	site-determining protein
A3L09_09345	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
A3L09_09350	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
A3L09_09410	ENOG4107UX3	phosphatidylethanolamine N-methyltransferase
A3L09_09415	ENOG4105DIW	FeS assembly protein SUFB
A3L09_09420	ENOG4105C3K	feS assembly ATPase SufC
A3L09_09455	ENOG4105C5I	Dehydrogenase
A3L09_09460	ENOG4107XGZ	Hydrolase
A3L09_09470	ENOG4105CIH	Imidazole acetol-phosphate transaminase
A3L09_09475	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
A3L09_09480	ENOG4105C9M	aspartyl-trna synthetase
A3L09_09510	ENOG4107XPA	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
A3L09_09515	ENOG4105GSQ	TM1410 hypothetical-related protein
A3L09_09520	ENOG41085AN	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
A3L09_09530	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
A3L09_09535	ENOG4108K7V	UPF0284 protein
A3L09_09550	ENOG4105C11	sulfate adenylyltransferase), subunit 2
A3L09_09580	ENOG4105D9P	serine threonine protein kinase
A3L09_09600	ENOG4105D9P	serine threonine protein kinase
A3L09_09605	ENOG4108ZF3	Phosphatase
A3L09_09610	ENOG4105D9P	serine threonine protein kinase
A3L09_09620	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
A3L09_09630	ENOG4105D9P	serine threonine protein kinase
A3L09_09635	ENOG4107QX8	SPFH domain, Band 7 family protein
A3L09_09645	ENOG4107104	thymidine kinase
A3L09_09660	ENOG4107QSA	Oxaloacetate decarboxylase
A3L09_09665	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
A3L09_09695	ENOG4105F0N	pyrophosphate phospho-hydrolase
A3L09_09745	ENOG4105DHP	deoxycytidine triphosphate deaminase
A3L09_09760	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
A3L09_09765	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
A3L09_09780	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
A3L09_09795	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
A3L09_09825	ENOG4108T9Q	UPF0278 protein
A3L09_09870	ENOG4105KME	endoribonuclease L-psp
A3L09_09880	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
A3L09_09890	ENOG4108VVK	transcriptional Regulator, AsnC
A3L09_09900	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
A3L09_09915	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
A3L09_09920	ENOG4105CHU	acetyl-coa acetyltransferase
A3L09_09995	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
A3L09_10005	ENOG4108ZPQ	MazG nucleotide pyrophosphohydrolase
A3L09_10015	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
A3L09_10025	ENOG4105CMQ	Chloride channel
A3L09_10075	ENOG4107WCI	zn-dependent hydrolase of the beta-lactamase fold-like protein
A3L09_10080	ENOG4107V9E	glucose-1-phosphate thymidylyltransferase
A3L09_10090	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
A3L09_10110	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
A3L09_10120	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
A3L09_10135	ENOG4107T8Q	Glycosyl transferase (Group 1
A3L09_10140	ENOG4105CGN	Glycosyl transferase (Group 1
A3L09_10160	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
A3L09_10175	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
A3L09_10220	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
A3L09_10235	ENOG4105M7V	2'-5' rna ligase
A3L09_10260	ENOG4108PCN	EamA-like transporter family
A3L09_10290	ENOG410838F	Glycosyl transferase family 2
A3L09_10325	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
A3L09_10330	ENOG4107YZX	Universal stress protein
A3L09_10335	ENOG4108UUC	Protein of unknown function DUF99
A3L09_10345	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
A3L09_10390	ENOG4105C5F	glutamine synthetase
A3L09_10405	ENOG4108JQ7	(ABC) transporter
A3L09_10410	ENOG4105C3U	ABC transporter
A3L09_10415	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
A3L09_10430	ENOG4105CD3	dihydroorotase
A3L09_10435	ENOG4105DF0	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity)
A3L09_10470	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
A3L09_10475	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
A3L09_10485	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
A3L09_10505	ENOG4107GFK	fumarate
A3L09_10510	ENOG4105C6K	Malic enzyme
A3L09_10530	ENOG4107S5Z	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation (By similarity)
A3L09_10565	ENOG4105EHU	Circadian clock protein KaiC
A3L09_10575	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
A3L09_10580	ENOG4107QT7	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
A3L09_10585	ENOG4105C3D	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
A3L09_10590	ENOG4105C1A	potassium transporter peripheral membrane
A3L09_10615	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation